CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP022266	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plB, complete sequence	0 crisprs	NA	0	0	0
NZ_CP022265	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plC, complete sequence	0 crisprs	NA	0	0	0
NZ_CP022264	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence	0 crisprs	NA	0	0	10
NZ_CP022263	Xanthomonas citri pv. vignicola strain CFBP7111 chromosome, complete genome	7 crisprs	cas3,DinG,WYL,DEDDh,csa3	2	7	15

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 9001

Brevibacillus_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113656.1\|638_1079_+	type IV pilus biogenesis protein PilM	NA	NA	NA	NA
WP_089113657.1\|1310_1670_+	hypothetical protein	NA	NA	NA	NA
WP_089113658.1\|1747_2386_-	DotA/TraY family protein	NA	NA	NA	NA
WP_089113660.1\|2845_4030_-	DotA/TraY family protein	NA	NA	NA	NA
WP_089113661.1\|4429_4933_+	hypothetical protein	NA	NA	NA	NA
WP_089113662.1\|4922_5423_+	hypothetical protein	NA	NA	NA	NA
WP_089113663.1\|5422_6559_+	hypothetical protein	NA	NA	NA	NA
WP_089113664.1\|6558_7389_+	hypothetical protein	NA	NA	NA	NA
WP_089113665.1\|7385_8000_+	hypothetical protein	NA	NA	NA	NA
WP_089113666.1\|7996_9001_+	M23 family metallopeptidase	A0A0K2CNY2	Brevibacillus_phage	2.1e-11	38.1

DBSCAN-SWA_2

14487 : 15171

Ralstonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113758.1\|14487_15171_+	lytic transglycosylase domain-containing protein	A0A0K2QQJ4	Ralstonia_phage	7.4e-05	32.4

DBSCAN-SWA_3

23882 : 25289

Salmonella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_167382373.1\|23882_25289_+	replicative DNA helicase	A0A1B0VG30	Salmonella_phage	1.5e-108	49.3

DBSCAN-SWA_4

31887 : 33393

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113760.1\|31887_33393_-	ATP-dependent helicase	A0A126DN25	Acinetobacter_phage	1.8e-48	33.7

DBSCAN-SWA_5

36945 : 75380

Escherichia_phage(22.22%)

integrase,transposase

attL 35960:35974|attR 70226:70240

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
35960:35974	attL	NA	NA	NA	NA
WP_089113692.1\|36945_38619_-	hypothetical protein	A0A097PAN8	Delftia_phage	2.8e-21	30.7
WP_089113693.1\|38664_38967_-	hypothetical protein	NA	NA	NA	NA
WP_089113761.1\|39790_40264_+	hypothetical protein	NA	NA	NA	NA
WP_089113694.1\|40346_40925_+	hypothetical protein	NA	NA	NA	NA
WP_089113695.1\|40924_41998_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_089113762.1\|43377_44925_-	HAD hydrolase-like protein	NA	NA	NA	NA
WP_029996442.1\|46271_47234_+\|transposase	IS1595-like element IS1595 family transposase	NA	NA	NA	NA
WP_014090219.1\|47409_48465_-	DNA-binding protein	NA	NA	NA	NA
WP_089113696.1\|49625_52586_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.5e-78	25.3
WP_089113697.1\|52694_54269_+	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_089113698.1\|54282_57261_+	conjugative relaxase	NA	NA	NA	NA
WP_003490829.1\|57549_57834_+	hypothetical protein	NA	NA	NA	NA
WP_029220895.1\|58019_59207_-	hypothetical protein	NA	NA	NA	NA
WP_029220894.1\|59213_59501_-	hypothetical protein	NA	NA	NA	NA
WP_005917856.1\|59526_59850_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_005917854.1\|59846_60068_-	antitoxin MazE family protein	NA	NA	NA	NA
WP_046932484.1\|60265_60832_+	recombinase family protein	Q71TD8	Escherichia_phage	1.8e-44	53.6
WP_089113699.1\|61060_61711_+	recombinase family protein	NA	NA	NA	NA
WP_089113700.1\|61785_62139_+	hypothetical protein	NA	NA	NA	NA
WP_089111531.1\|63044_64188_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-89	58.8
WP_089113702.1\|64730_65042_-	hypothetical protein	NA	NA	NA	NA
WP_011795799.1\|65062_65761_-	UPF0149 family protein	G9E3U3	Emiliania_huxleyi_virus	9.9e-05	74.1
WP_089113703.1\|67088_67307_-	hypothetical protein	NA	NA	NA	NA
WP_089113763.1\|68363_68570_+	hypothetical protein	NA	NA	NA	NA
WP_089111307.1\|69132_70219_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_089111250.1\|70581_71562_-\|transposase	IS5 family transposase	A0A077K814	Ralstonia_phage	8.8e-100	61.6
70226:70240	attR	NA	NA	NA	NA
WP_129560231.1\|71944_72370_-	hypothetical protein	A0A1B0VMH3	Pseudomonas_phage	1.3e-12	44.0
WP_017116034.1\|72477_73572_-	BsuBI-PstI family restriction endonuclease	NA	NA	NA	NA
WP_089113704.1\|73568_75380_-	N-6 DNA methylase	G9L6H9	Escherichia_phage	4.5e-25	25.8

DBSCAN-SWA_6

78456 : 80484

Roseobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113707.1\|78456_80484_-	DEAD/DEAH box helicase	A0A1B0UY08	Roseobacter_phage	3.3e-24	24.6

DBSCAN-SWA_7

86210 : 90161

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157768235.1\|86210_86741_-	hypothetical protein	A0A2H4JDN1	uncultured_Caudovirales_phage	8.5e-25	50.3
WP_089113714.1\|87017_87758_-	EAL domain-containing protein	NA	NA	NA	NA
WP_089113766.1\|87983_90161_-	conjugal transfer protein TraE	A0A1X9I6W8	Streptococcus_phage	3.5e-32	27.1

DBSCAN-SWA_8

114506 : 115850

Ochrobactrum_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113733.1\|114506_115850_+	AAA family ATPase	A0A240F4U1	Ochrobactrum_phage	1.2e-35	29.5

DBSCAN-SWA_9

134220 : 135744

Aeromonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113750.1\|134220_135744_+	shufflon system plasmid conjugative transfer pilus tip adhesin PilV	H6UK37	Aeromonas_phage	5.0e-09	55.9

DBSCAN-SWA_10

143112 : 144117

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113666.1\|143112_144117_+	M23 family metallopeptidase	A0A0K2CNY2	Brevibacillus_phage	2.1e-11	38.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP022263

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022263_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022263_1

29071-29424

Orphan

Consensus_repeat	Method
NTGGAAACGGTCAACGGC	CRT
TGGAAACGGTCAACGGC	PILER-CR
TGGAAACGGTCAATGGCAGCATC	CRISPRCasFinder

6 spacers

WYL

The CRISPR arrays of NZ_CP022263_1

>merge|NZ_CP022263|1|29071-29424|CRT,PILER-CR,CRISPRCasFinder
GTCAGCAAGGTCAACGGCAAGATCAGCGCAGATGCCGGCAAGACCTATGGCGCCCTGGAAACGGTCAACGGCTCCATCGAGATCGGTGCCGGTGCGCAAACCAAGAACGTGGAAACCGTCAACGGCGGCATCCGCATCGGCGACAACGCGCGTACCGGGGGCGTGGAAACGGTCAACGGCTCGATCACGCTGGGCCAGAAGGTGATCGTGTCCGGCGGACTGGAAACGGTCAATGGCAGCATCCTCGCCGAGCGCGGCAGCCAGATCAGTGGCGGGGTGGAAACGGTCAACGGCAGCATCGGGCTGGTGGGGACCGAGCTCGGCAAGGGCATCGAGACGGTCAATGGCGACATC

>NZ_CP022263|1|1|29071-29418|CRT
GTCAGCAAGGTCAACGGC	AAGATCAGCGCAGATGCCGGCAAGACCTATGGCGCC
CTGGAAACGGTCAACGGC	TCCATCGAGATCGGTGCCGGTGCGCAAACCAAGAAC
GTGGAAACCGTCAACGGC	GGCATCCGCATCGGCGACAACGCGCGTACCGGGGGC
GTGGAAACGGTCAACGGC	TCGATCACGCTGGGCCAGAAGGTGATCGTGTCCGGCGGA
CTGGAAACGGTCAATGGC	AGCATCCTCGCCGAGCGCGGCAGCCAGATCAGTGGCGGG
GTGGAAACGGTCAACGGC	AGCATCGGGCTGGTGGGGACCGAGCTCGGCAAGGGC
ATCGAGACGGTCAATGGC

>NZ_CP022263|1|1|29126-29364|PILER-CR
TGGAAACGGTCAACGGC	TCCATCGAGATCGGTGCCGGTGCGCAAACCAAGAACG
TGGAAACCGTCAACGGC	GGCATCCGCATCGGCGACAACGCGCGTACCGGGGGCG
TGGAAACGGTCAACGGC	TCGATCACGCTGGGCCAGAAGGTGATCGTGTCCGGCGGAC
TGGAAACGGTCAATGGC	AGCATCCTCGCCGAGCGCGGCAGCCAGATCAGTGGCGGGG
TGGAAACGGTCAACGGC

>NZ_CP022263|1|1|29126-29424|CRISPRCasFinder
TGGAAACGGTCAACGGCTCCATC	GAGATCGGTGCCGGTGCGCAAACCAAGAACG
TGGAAACCGTCAACGGCGGCATC	CGCATCGGCGACAACGCGCGTACCGGGGGCG
TGGAAACGGTCAACGGCTCGATC	ACGCTGGGCCAGAAGGTGATCGTGTCCGGCGGAC
TGGAAACGGTCAATGGCAGCATC	CTCGCCGAGCGCGGCAGCCAGATCAGTGGCGGGG
TGGAAACGGTCAACGGCAGCATC	GGGCTGGTGGGGACCGAGCTCGGCAAGGGCA
TCGAGACGGTCAATGGCGACATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022263.1\|WP_089111253.1\|19370_19736_+\|DUF1330-domain-containing-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089111263.1\|41480_45953_-\|glutamate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236968
NZ_CP022263.1\|WP_089111255.1\|24825_25818_+\|D-2-hydroxyacid-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|240646
NZ_CP022263.1\|WP_003482177.1\|23704_24397_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NZ_CP022263.1\|WP_089111260.1\|36266_37340_-\|glycoside-hydrolase-family-5-protein	unknown	unknown	gnl\|CDD\|365907
NZ_CP022263.1\|WP_022557784.1\|19865_20993_-\|PA0069-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|275263
NZ_CP022263.1\|WP_089111258.1\|31929_32373_-\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|379323
NZ_CP022263.1\|WP_089111259.1\|32668_33802_-\|glycoside-hydrolase-family-5-protein	unknown	unknown	gnl\|CDD\|365907
NZ_CP022263.1\|WP_033481293.1\|27608_28844_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|227278
NZ_CP022263.1\|WP_089111262.1\|39802_41284_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|273553
NZ_CP022263.1\|WP_089111256.1\|25980_27504_-\|S41-family-peptidase	unknown	unknown	gnl\|CDD\|223864
NZ_CP022263.1\|WP_099802644.1\|39434_39788_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089111254.1\|22145_23486_-\|outer-membrane-protein-transport-protein	unknown	unknown	gnl\|CDD\|367457
NZ_CP022263.1\|WP_089111257.1\|29822_31619_+\|M28-family-peptidase	unknown	unknown	gnl\|CDD\|349910
NZ_CP022263.1\|WP_089113423.1\|21177_21879_-\|2OG-Fe(II)-oxygenase	unknown	unknown	gnl\|CDD\|379309
NZ_CP022263.1\|WP_089111252.1\|18596_19322_+\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP022263.1\|WP_057661749.1\|24505_24826_+\|DUF1820-family-protein	unknown	unknown	gnl\|CDD\|370154
NZ_CP022263.1\|WP_022557795.1\|37648_38707_+\|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176186
NZ_CP022263.1\|WP_089111261.1\|38815_39391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_007968174.1\|34439_35492_-\|glycoside-hydrolase-family-5-protein	unknown	unknown	gnl\|CDD\|365907

Protein	Function_ID	Function_description	E-value
NZ_CP022263.1\|WP_089111263.1\|41480_45953_-\|glutamate-synthase-large-subunit	gnl\|CDD\|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NZ_CP022263.1\|WP_089111255.1\|24825_25818_+\|D-2-hydroxyacid-dehydrogenase-family-protein	gnl\|CDD\|240646	cd12169, PGDH_like_1, Putative D-3-Phosphoglycerate Dehydrogenases. Phosphoglycerate dehydrogenases (PGDHs) catalyze the initial step in the biosynthesis of L-serine from D-3-phosphoglycerate. PGDHs come in 3 distinct structural forms, with this first group being related to 2-hydroxy acid dehydrogenases, sharing structural similarity to formate and glycerate dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily, which also include groups such as L-alanine dehydrogenase and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. Many, not all, members of this family are dimeric.	4.56405e-142
NZ_CP022263.1\|WP_003482177.1\|23704_24397_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	1.19314e-25
NZ_CP022263.1\|WP_089111260.1\|36266_37340_-\|glycoside-hydrolase-family-5-protein	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	1.71559e-61
NZ_CP022263.1\|WP_022557784.1\|19865_20993_-\|PA0069-family-radical-SAM-protein	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	1.44405e-23
NZ_CP022263.1\|WP_089111259.1\|32668_33802_-\|glycoside-hydrolase-family-5-protein	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	1.21052e-57
NZ_CP022263.1\|WP_033481293.1\|27608_28844_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	3.65433e-91
NZ_CP022263.1\|WP_007968174.1\|34439_35492_-\|glycoside-hydrolase-family-5-protein	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	1.04404e-59
NZ_CP022263.1\|WP_089111262.1\|39802_41284_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|273553	TIGR01318, glutamate_synthase_small_subunit_gltD, glutamate synthase small subunit family protein, proteobacterial. This model represents one of three built for the NADPH-dependent or NADH-dependent glutamate synthase (EC 1.4.1.13 and 1.4.1.14, respectively) small subunit and homologs. TIGR01317 describes the small subunit (or equivalent region from longer forms) in eukaryotes, Gram-positive bacteria, and some other lineages, both NADH and NADPH-dependent. TIGR01316 describes a protein of similar length, from Archaea and a number of bacterial lineages, that forms glutamate synthase homotetramers without a large subunit. This model describes both glutatate synthase small subunit and closely related paralogs of unknown function from a number of gamma and alpha subdivision Proteobacteria, including E. coli.	0
NZ_CP022263.1\|WP_089111256.1\|25980_27504_-\|S41-family-peptidase	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	4.19257e-128
NZ_CP022263.1\|WP_089111258.1\|31929_32373_-\|PepSY-domain-containing-protein	gnl\|CDD\|379323	pfam13670, PepSY_2, Peptidase propeptide and YPEB domain. This region is likely to have a protease inhibitory function (personal obs:C Yeats). The name is derived from Peptidase & Bacillus subtilis YPEB.	1.29506e-05
NZ_CP022263.1\|WP_089111257.1\|29822_31619_+\|M28-family-peptidase	gnl\|CDD\|349910	cd05660, M28_like_PA, M28 Zn-peptidase containing a protease-associated (PA) domain insert. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. This subfamily is composed of uncharacterized proteins containing a protease-associated (PA) domain insert which may participate in substrate binding and/or promote conformational changes, influencing the stability and accessibility of the site to substrate.	1.39308e-121
NZ_CP022263.1\|WP_089113423.1\|21177_21879_-\|2OG-Fe(II)-oxygenase	gnl\|CDD\|379309	pfam13640, 2OG-FeII_Oxy_3, 2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily.	1.20597e-07
NZ_CP022263.1\|WP_089111252.1\|18596_19322_+\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.71823e-54
NZ_CP022263.1\|WP_057661749.1\|24505_24826_+\|DUF1820-family-protein	gnl\|CDD\|370154	pfam08850, DUF1820, Domain of unknown function (DUF1820). This family includes small functionally uncharacterized proteins around 100 amino acids in length.	7.75601e-52
NZ_CP022263.1\|WP_022557795.1\|37648_38707_+\|NAD(P)-dependent-alcohol-dehydrogenase	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP022263.1\|WP_089111254.1\|22145_23486_-\|outer-membrane-protein-transport-protein	gnl\|CDD\|367457	pfam03349, Toluene_X, Outer membrane protein transport protein (OMPP1/FadL/TodX). This family includes TodX from Pseudomonas putida F1 and TbuX from Ralstonia pickettii PKO1. These are membrane proteins of uncertain function that are involved in toluene catabolism. Related proteins involved in the degradation of similar aromatic hydrocarbons are also in this family, such as CymD. This family also includes FadL involved in translocation of long-chain fatty acids across the outer membrane. It is also a receptor for the bacteriophage T2.	1.07835e-134

>NZ_CP022263.1|WP_033481293.1|27608_28844_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MWLAVGVLACTLLGSMGASAQSQRETERKLQQLRDELKTISADRRELEGKRGTAAQQLRQADEKVAKTARALSETEAAMRAQEQHLSSLQQERAQLQRGLQSQRTQLAALLRAADQVGRNAPLKVLLSQDTVGDATRMLADHRYVQNARAQRIHALTTQLDALATVEQDIATRRQALDAARAQQKAQAATLQKDRSQQAATVAQLDDRYKQRAEREKAIGQDAKALEQLLANLRAAAAKAEAERRAAARRAAAEAAAQAKRSKTERSDRPGKTPPKVIANAPAPKVGGLSWPVAGNLLARFNATLPDGHTSKGVLIGAPKGTTVTAVADGTVVFSDWMTGYGMILIVDHGNGYMSLYAHNDTLLRDAGASIKRGDAVAKVGSSGGQGVPALYFELRRNGQPVDPSSWLQRR
>NZ_CP022263.1|WP_089111256.1|25980_27504_-|S41-family-peptidase
MRVAVLSVALSLALFASPGWAQKAGPAAAQASADDPEANEAAVSKVPLDEIRRFVAVYNAVKQAYVDPVEDKKLMHAAVRGLLSDLDPHSTYFDKEDAEAFDEQATGAYDGIGVELLQQQDNTLKVIAPIDDTPAARAGIRAGDVIVAIDGKPIDASKAMEPLRGESGSKVVLTIMRDKTPKPFDVTLQRETIRVASVRSKLLEPGYGYIRISTFQADTGADFQKNVKQLQAGGKLRGLVLDLRSNPGGLLTSAVQVADDLLDKGNIVSTRGRISISDAKFDATPGDLLNGAPVVVLVDAGSASASEVLAGALRDNKRARIIGSRTFGKGSVQTVLPLDNGDSVKLTTARYYTPSGKSIQASGIVPDVLLTPEPQPGDADAPASLTDYSEATLPGHLRGDDEGEEGYSAGDVLPGDGPITEALAELKQPGAAAKAQAARKAKAQAAQKAKAAKTGAEPKPAAARPATTDKPRSAEPASKAKPATAPAAPAEPVQPTPPADKPAEPVN
>NZ_CP022263.1|WP_089111255.1|24825_25818_+|D-2-hydroxyacid-dehydrogenase-family-protein
MRVVVPDDYQGAVARLPCLQQLQGHQVQVLGALDEALDARAACLADADALVLIRERTRVDAALLQRLPRLKLISQTGRVGAHVDVAACTALGVAVAEGVGSPVAPAELTWALILSASRRLTDYQHALQQGRWQALGDPGLGRVLHGRTLGIWSYGRIGQRLAGFGRAFGMQVLVWGGEASCAQAARDGFAVAGSREELFERSDVLSLHRRLTAQTRHDITAQDLARMRDDALLVNTSRAELIAPGALLAALDAGRPAQAALDVFEHEPVLDPRDSLLRHVRVLATPHLGYVERDSYALYFDAAFDNVLAFAAGTPRNLVNPEVLATTQRA
>NZ_CP022263.1|WP_057661749.1|24505_24826_+|DUF1820-family-protein
MSKPLYKVTFLNHGKVYELYAREVTGSHLWGFNQIGELVFDVHDGLVVDPTEERLREEFGNTRTLHLPMQSIVRIEEVQKKGQSVIRDATTGDKVVTPFPSPIKPR
>NZ_CP022263.1|WP_003482177.1|23704_24397_+|rhomboid-family-intramembrane-serine-protease
MFVSLPSRKKPTPRWAVPLLFATVWLAYLWSISRPGEARNTLWLDWGALSSGVSNLGDWWATLRDGSVLRLFTALFLHADWSHLLGNLVFLLIFGLPAERILGPWRLLLLFLVGGAASNLAAIFAIGTPDRVIIGASGAVSALIGTYLALFPGAKLGVVLPLGVFLEFIRVPAPLLIGAWALLQVVFAYIGPAFGMVAWSAHIAGFVFGIVYGLYVRAAIARRLRKRHGF
>NZ_CP022263.1|WP_089111254.1|22145_23486_-|outer-membrane-protein-transport-protein
MSTASTLSRATLLAVGIAGVLAVGQAHGAAFQLKENSAKGLGRAFAGSGSAPDDASIIATNPAGMRQLDGRLFQADVSAISFSAKFQPDTAAYANGAPVSGGNGGDAGMIAPVPALYFHVPFGENDNMHLGTSLTVPFGFKTEYDRDWVGRYHGTKTELQAIDFNVAFSYDVNPYVSFGASVFAERLDIDLANAVDFGSVLAARRVPGFAPGSADGYSRIKGDSTEVGFTLGGLFSIDENTHIGFSYRSQVEHKITDGTADFTVPGSAAAVLSVAAPGTFVDTKGRATVKLPASATASFTHNVNEQWSIMADVTRTAWSKFDQVTVDFASNQPDSVLDFSYRDTTFASIGADYRLSDTVTLRGGLAYDQTPTTAEHRDVRVPDASRKWVSLGMSWRPSAQTEYNFGYTHLFTSDPTSDTRSATADRLAGSYDVKGDVLAASINYKF
>NZ_CP022263.1|WP_089113423.1|21177_21879_-|2OG-Fe(II)-oxygenase
MSQPDFIQITDNAIAHEECVAIVQRMRQSQQLHPGRIGGGVFPDLKHSRDLRISGMAEWAEVENRLQQAVFEGVLTYLRQYPQALISPLMLQVTTADGTRHRLVAEDIVQMSDQALGDLARTCLRPGAINLQWYTADQGGYPYWHCELYPRDANADTLHRHLLWTLYLNDDFAQGETEFLFQQRKARPRTGSLLIAPTAFTHTHRGNRPVGGDKFIATSWILFQSAQALYGGE
>NZ_CP022263.1|WP_022557784.1|19865_20993_-|PA0069-family-radical-SAM-protein
MQKNSSPSASAAAERDVRSSRTVIKGRGTTAYVPGRFSVTTAVEIDDGWGALDADGETAFRPKTVVAEEIARSIISRNNSPDIGFSQSVNPYRGCEHGCVYCFARPSHAYLDLSPGLDFETRIFAKPNAAALLRAEIARPSYQCSPIALGINTDAYQPAERRLHISRQCLEVLAQARHPVSFVTKAALIERDIDVLAEMAQHNLVSVYFSVTTLDNRLAAKMEPRAAAPHARLRAMQALHAAGVPVGVLVAPVIPMINDKELERILDAAAAHGARSAGYVLLRLPHELTQLWREWLELHYPDRAKHVMSLIQQMRGGKDYDSRFGKRMVGEGPFAELIAQRFSIAYRRLGFGRLPRLDTTQFRPPRPDTPQLDLF
>NZ_CP022263.1|WP_089111253.1|19370_19736_+|DUF1330-domain-containing-protein
MVAFSPNALSAFLDNQDTSAIVMLNLIRFQADGGRERYHRYLRLATPILARFDAHIVFSGDGLPVLTAGQAQAWDAVTLVQYPGRSAFKQMIADAEYQQAFEVGRSAIAEIVLQPFHGITL
>NZ_CP022263.1|WP_089111252.1|18596_19322_+|YafY-family-transcriptional-regulator
MSRTTRLFELLGLLRAHRRPVSAAALASELGVSQRSLYRDIDTLRALGAPLEGQAGVGYYLKPGFFLPSLAFSQEELDAVMLGLDWVKQRADPALARCGESALAKILSARKHGDGTGIDVAPPAILTAASTSEAVDHPQTAVLRDAIRRQCKLAIGYVDAQDTPSERIVWPIALVYFDDVRVLAAWCERRSAFRHFRVDRLQVRAVLKARYPQSRQALVKQWRQQDRDWRSLLTVSDTAQR
>NZ_CP022263.1|WP_089111257.1|29822_31619_+|M28-family-peptidase
MPRKILLCLAATLALAGCKREPADAPSAPAAQTPTESAPSAPVSRHTFSPDMTTGDFAELVKTLASDDFEGRGPGTPGEEKTVTYIRDQMQRIGLQPGNGDSWFQEVPMVETAADASTAPSLRSGEQTRTLAFGTDIVVGTRTGQAEVKLDNSELVFVGYGVDAPEQQWNDYAGQEWKGKTVVMFVNDPGFHTDDAKLFDGKRMTYYGRWTYKFEEAARKGAAAALIVHDTPGASYGWDVVKNSWSGPQYDLPAKDDPDPRLPVQGWISAETARQLFANAGLDLAQAYKDASKRGFKPVPLKASWSVDLKSTIAAKTSRNVVGVLPGTSHADEAVLYMAHWDHLGKHPGESGDNIYNGAVDNATGVAGILEIADAFAHQDPKPARSVVFLAVTLEESGLLGSKYYVANPSFPLDKIAAVINLDAMSVAGRARDVTVVGMGSSELEDILKPIAAMQGRTLHAEATPQNGSYFRSDHFNFAKAGVPALYADGGDDLREGGTAAGRAAAEEYGRHRYHAPGDEYDAATWKLDGTIEDLQVVYGVGKQVAAGERWPNWYPGNPFKAARDRMMAGRPGTSAASAQPADATSTATQTNTANPPR
>NZ_CP022263.1|WP_089111258.1|31929_32373_-|PepSY-domain-containing-protein
MTQRLMKTALIGALALLSQGALAQAADKPAKAFTSGEVTSMLTAKGYTKVHDVKFEHGVWTADARSGDGKDVDVHIDPVTGRVYGDQTTSKLSEADVRASLSTGGYADVHDLKFTDGLWKADAKRNGQKVELHVDPEDGHVVSVDND
>NZ_CP022263.1|WP_089111259.1|32668_33802_-|glycoside-hydrolase-family-5-protein
MSAVCFSLRTLLRSTLLFIVFGSLPLAHAQTRALTYAGVNLSGAEYASSKKPGVLNKDYMYAAASDYTYFAGVGMNTIRLPILWERLQPTGGGELDPAQLALLQQAVARAKAAGMYLVIDIHNYAKYYGYKIGSPEVPVATFTDLWRRLALVFNSDNAVMFGLMNEPNNISASEWAGAAQAAIDAIRRTGANNLILVPGALWTGAHSWYSTTNDGYSNATALTSIYDPLDRYAFEVHQYLDADSSGTSSTCVSSTIGAERLRNFTQWLRTNRKRGFLAEFGTANNAVCNQALQGMLSHMETNADVWLGWTWWAAGSWWNLSYAYSVHPNKDGTDKPQMAILSPQAALATRAPVAAAAARTSAASTSATSVSVARTTR
>NZ_CP022263.1|WP_007968174.1|34439_35492_-|glycoside-hydrolase-family-5-protein
MKSLTTHTRRLRCRALSFLLLATMPLAQAQSATGLKYAGVNLSGAEIKSSQKPGVLNIDYRYPAADEYAYFAGKHMNTVRLPILWERLQPRAGGELDPAQLALIRQAVANAKAAKMYVIVDVHNYAKYYGHTIGSTKVPISTFNDLWRRLAIAFKSDNAVIFGLMNEPYDIDPQAWATAAQASIDTIRKTGATNLILVPGALWTGAHSWYSTVAGQSNAVAMASIRDPLNRYAIEAHQYLDADSSGTSGGCVSATVGVERLRSFTEWLRLNKKRGFLAEFGTGNTVTCNLALNGMLGYMESNGDVWMGWSWWAAGAWWSGAYPFNVQPDAQGRDKPQMSILSPRARRITD
>NZ_CP022263.1|WP_089111260.1|36266_37340_-|glycoside-hydrolase-family-5-protein
MFRTPPHLSRLRTAALALTLIAAIPLVQAKEPAGPKKESAGLKYVGVNLSGAEFNSRKKPGTLFKDYTYPAASDFSYFAGKGMNTIRLPFLWERVQPELNGPLDQAQLGLIKKSLEAAKANKQYLILDLHNYATYSGKRIGTSDVPASALADLWRRLALEFKDDKAVIFGLMNEPNGISAPDWASAAQGTINAIRKTGAKNLILVPGTAYTGAHSWRSTSYGVSNAKALEILKDPGNNLAFEAHQYLDKDYSGTKPVCTSDSVGQEKLQGFTSWLRENKQKGFLGEFATANNPVCDKALEGMLTYMEKNSDVWLGWTWWAAGSWWKPDYPFTVQPGKDGSDKPQMAILSKYARRAGK
>NZ_CP022263.1|WP_022557795.1|37648_38707_+|NAD(P)-dependent-alcohol-dehydrogenase
MSTAHAYAAQAADQPLAPFVFERRAPGPNDVQIDIAYCGVCHSDLHTARNEWHNTLYPSVPGHEIVGRVTAVGNAVTGFKVGDLAGVGCMVDSCRSCASCQEGEEQYCEAGFTGTYNGPMFGGGENTYGGYSDHIVVDQKYVLRITHSDNLAAVAPLLCAGITTYSPLAHWKVGPGQKVGVVGLGGLGHMAVKIAKAMGATVVLFTTSESKRADALRLGASEVVISKDEAQMAAQYNTLDFILNTVAAPHNLDPFLNALKRDGAMVLVGVPEQSHPSPAVFNLIMKRRTLAGSLIGGIRQTQEMLDFCAKHNIVSDIETIRADQINAAYERMLKSDVKYRFVIDMATLDKAA
>NZ_CP022263.1|WP_089111261.1|38815_39391_-|hypothetical-protein
MTIAIYIDSCAWNYLHDRAIDLATELPSDIYTLHLTREVEIELEAIPNGGKKEALKAYIFASIERCSIKTASVFGFQTLESDGLPSKAQVYGGFGQGTFQSDADRKFYALPEVKCQLRGKSSRKTGLSNNQADASLAARSFGAFVLTNDEKPGPLKLAADKGGKIVYLAEEVDKSGLTLGEYMSRLRQSIE
>NZ_CP022263.1|WP_099802644.1|39434_39788_-|hypothetical-protein
MLRSLFTCLLILTASSAIAAPAATCQESDNLRFDGFPLSIVQMEQIGLTYAAKNTKAPQVPFAYANKDWLWLKEQYRPGDYFLAYEQLWPASGKPFASGYALVRGRCVLGVLSIRVS
>NZ_CP022263.1|WP_089111262.1|39802_41284_-|FAD-dependent-oxidoreductase
MSRKQAFQFLDLPRTMPTRIPVELRTSGDWGELYGRFDKADAQYQAGRCLDCGNPYCSWKCPVHNAIPQWLQLVQENRIEEAAALCHSTNPLPEVCGRVCPQDRLCEGSCTLEEFGAVTIGAVEKYIVDTAFKMGWRPDLGNVQPSGHRVAVIGAGPAGLACADRLARAGIEAVVYDRYEQIGGLLQFGIPSFKLDKSVIGKRREILEGMGVQFRLGVEIGKDISIEQLLAEYDAVFLGTGAYRYTDGGLPGQDLKNVLPALPFLVQNSRIVSGNDPHGRPIAGWEDQLALPDLTGKRVVVLGGGDTGMDCVRSAIRLGAAKVTCAYRRDEASMPGSAREVANAREEGVRFLFNRQPLSIESGADDEAIGVTVVETKLGEPDASGRRNAVPVEGSESLLEADVVIIAFGFSPTLPDWLASQGVEAGSNGRIVAPADGNGRLPYQTTNPRLFAGGDCVRGADLVVTAVAEGRDAAGSIVQMLGVKAQVKEPAAA
>NZ_CP022263.1|WP_089111263.1|41480_45953_-|glutamate-synthase-large-subunit
MAPRTRQGLNDDGLYNSVRDERDACGFGMVAQLDDQPSRALVDTAIAALSRMTHRGGVAADGLTGDGCGLLIRKPDAFLRGLARDAGIALGTRYAAGVVFLPLDEADAARCRAELEAQLHSAGVHLRGWRVVPTDDSVCGQLARDTLPRIEQVFVDAGAEQTEDGFTLALFLARRRAEQALHAVENFYVTTLSPNGISYKGMVLPDKLSTFYPDLQRSDLSSSAIVFHQRFSTNTLPRWPLAHPFRLLAHNGEINTIEGNRRWAQARSKVWQTPRFDIAQFDPVISMHGSDSQSLDNMLELLIAGGMDLLQALRILVPPATQSLEFKDADLAAFYEFYGLNTEPWDGPAGIVACDSRYAACMLDRNGLRPARWMLTSDRHFLVASEAGVWELPAERITRKGKLGPGEMMAIDLKRGDLLDSDAIDRINRARAPYKQWLQQGVTYLQTELIDPSLVEEPFSEQTLRSYHKLFQLSTEEVEQVLRPLTETEQEATGSMGDDTPMAVLSRQTRPLYDYFRQAFAQVTNPPIDPLREGIAMSLTTQLGKETNIFHAGAETVNHVILNSPVLSQRKLRQLLKMEQYVERNRLIDLSYSLEEGLKAGLERICQEVEAAARAGAVMLLLSDRYPVPDRPMAHALLATGAVHHHLCKVGLRCDVNLIIETGTARDPHHMACLLGVGATAVYPYLAYQTLFDLGRRGILQLSKGGEQSQIGRRYRKGIYKGLSKIISKMGICTIASYRGAQLFEIVGLDPDVVDLCFADTPARIGGVDLARLDTEARELTVRAWNDQLKPEVGGLLKYVHGGEYHMYNPDVVMTLQRATRTGDAGDWQKYVDAVHARPASTLRDLVQLKRADTPLPLDDVAPAEDVLRRFDSAAISLGALSPEAHEALAIAMNRLGGRSNSGEGGEDPARYGTEKRSKIKQVASGRFGVTPEYLVNAEVLQIKVAQGAKPGEGGQLPGHKVNELIARLRYAKPGIGLISPPPHHDIYSIEDLAQLIYDLKQVNPTALVSVKLVAHAGVGTIAAGVVKAGADLITVSGHDGGTGASPVSSIRYAGVPWELGVAESHQALVANDLRERTILQTDGGLKTGLDVVKAALLGADSFGFGTAPMIVLGCKYLRICHLNNCATGVATQDERLRAGYFTGLPERVEHFFRLLAEEVRQWLSYLGVRSLDEIVGRTDLLEQLDVSPRPGVKVDLSRLLTHAQYDGSHCAAQRLYESPDSLATQMDGLLADAIANKLGGDHRFLIHNTDRSIGARLSGAIARAHGNHGMSDAPLNLRFRGTAGQSFGAFNAGGLQLELEGEANDYVGKGMAGGRLVVRPPRGARFEARNTPIVGNTCLYGATGGELFAAGRAGERFAVRNSGALAVVEGAGDHCCEYMTDGVVLVLGKVGLNFGAGFTGGLAYVLDIERDFVDRYNHELIDIHRVSAEGFENHRQHLHTLISRHRELTGSIWAQQILDEFRDYIGKFWLVKPKAASIESLTESLRRAA

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Crispr_ID: NZ_CP022263_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022263_2

429460-429542

Orphan

Consensus_repeat	Method
GGTCTCCAACAGCGGCACCATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022263_2

>merge|NZ_CP022263|2|429460-429542|CRISPRCasFinder
GGTCTCCAACAGCGGCACCATCAATGCGGCGGCCGGCTCGGCCACGTTGATCGGCGGCCGGGTCGCCAACAGCGGCACCATCA

>NZ_CP022263|2|2|429460-429542|CRISPRCasFinder
GGTCTCCAACAGCGGCACCATCA	ATGCGGCGGCCGGCTCGGCCACGTTGATCGGCGGCCG
GGTCGCCAACAGCGGCACCATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022263.1\|WP_089111408.1\|426798_427260_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089111409.1\|427256_428933_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP022263.1\|WP_022560294.1\|442555_443455_-\|oxygen-dependent-coproporphyrinogen-oxidase	unknown	unknown	gnl\|CDD\|235413
NZ_CP022263.1\|WP_089113452.1\|415693_417028_+\|type-VI-secretion-system-baseplate-subunit-TssK	unknown	unknown	gnl\|CDD\|274536
NZ_CP022263.1\|WP_167382231.1\|450428_451436_-\|pteridine-dependent-deoxygenase	unknown	unknown	gnl\|CDD\|275237
NZ_CP022263.1\|WP_089111411.1\|438530_438821_-\|DUF2782-domain-containing-protein	unknown	unknown	gnl\|CDD\|378588
NZ_CP022263.1\|WP_082332431.1\|413168_414050_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176163
NZ_CP022263.1\|WP_089111414.1\|443891_444458_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089113454.1\|444454_445171_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089111403.1\|417009_418290_+\|type-VI-secretion-system-protein-TssL	unknown	unknown	gnl\|CDD\|180801
NZ_CP022263.1\|WP_089111412.1\|438897_441702_+\|DNA-polymerase-I	unknown	unknown	gnl\|CDD\|235591
NZ_CP022263.1\|WP_007972212.1\|449884_450229_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089111407.1\|423106_426802_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022263.1\|WP_089111415.1\|448528_449836_+\|acyl-CoA-synthetase	unknown	unknown	gnl\|CDD\|223442
NZ_CP022263.1\|WP_089111402.1\|414300_415191_+\|aldo/keto-reductase-family-oxidoreductase	unknown	unknown	gnl\|CDD\|236676
NZ_CP022263.1\|WP_089111406.1\|422385_423102_+\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NZ_CP022263.1\|WP_042676010.1\|445561_447922_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NZ_CP022263.1\|WP_089111405.1\|421813_422389_+\|type-VI-secretion-system-associated-protein-TagF	unknown	unknown	gnl\|CDD\|132416
NZ_CP022263.1\|WP_089113453.1\|437177_438221_+\|type-VI-secretion-system-protein-TssA	unknown	unknown	gnl\|CDD\|274544
NZ_CP022263.1\|WP_089111404.1\|418286_421817_+\|type-VI-secretion-system-membrane-subunit-TssM	unknown	unknown	gnl\|CDD\|274531

Protein	Function_ID	Function_description	E-value
NZ_CP022263.1\|WP_089111404.1\|418286_421817_+\|type-VI-secretion-system-membrane-subunit-TssM	gnl\|CDD\|274531	TIGR03348, VI_IcmF, type VI secretion protein IcmF. Members of this protein family are IcmF homologs and tend to be associated with type VI secretion systems. [Cellular processes, Pathogenesis].	0
NZ_CP022263.1\|WP_022560294.1\|442555_443455_-\|oxygen-dependent-coproporphyrinogen-oxidase	gnl\|CDD\|235413	PRK05330, PRK05330, oxygen-dependent coproporphyrinogen oxidase.	0
NZ_CP022263.1\|WP_089113452.1\|415693_417028_+\|type-VI-secretion-system-baseplate-subunit-TssK	gnl\|CDD\|274536	TIGR03353, VI_chp_4, type VI secretion protein, VC_A0114 family. Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP022263.1\|WP_167382231.1\|450428_451436_-\|pteridine-dependent-deoxygenase	gnl\|CDD\|275237	TIGR04444, hypothetical_protein_ThecoDRAFT_3161, chorismatase, FkbO/Hyg5 family. Members of this include two chemically distinct enzymes that cleave pyruvate from chorismate. FkbO and RapK convert chorismate to pyruvate plus (4R,5R)-4,5-dihydroxycyclohexa-1,5-dienecarboxylic acid (DCDC). HygB and Bra8 convert chorismate to pyruvate, water, and 3-hydroxybenzoate. These two enzymes are closely related, and lack homology to chorismate lyase, EC 4.1.3.40, which converts chorismate to pyruvate plus 4-hydroxybenzoate.	2.02612e-64
NZ_CP022263.1\|WP_089111403.1\|417009_418290_+\|type-VI-secretion-system-protein-TssL	gnl\|CDD\|180801	PRK07033, PRK07033, DotU family type VI secretion system protein.	5.45793e-118
NZ_CP022263.1\|WP_082332431.1\|413168_414050_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176163	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 5. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.60492e-91
NZ_CP022263.1\|WP_042676010.1\|445561_447922_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	3.13856e-78
NZ_CP022263.1\|WP_089111411.1\|438530_438821_-\|DUF2782-domain-containing-protein	gnl\|CDD\|378588	pfam11191, DUF2782, Protein of unknown function (DUF2782). This is a bacterial family of proteins whose function is unknown.	4.23324e-17
NZ_CP022263.1\|WP_089111412.1\|438897_441702_+\|DNA-polymerase-I	gnl\|CDD\|235591	PRK05755, PRK05755, DNA polymerase I; Provisional.	0
NZ_CP022263.1\|WP_089111407.1\|423106_426802_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.21741e-70
NZ_CP022263.1\|WP_089111402.1\|414300_415191_+\|aldo/keto-reductase-family-oxidoreductase	gnl\|CDD\|236676	PRK10376, PRK10376, putative oxidoreductase; Provisional.	0
NZ_CP022263.1\|WP_089111406.1\|422385_423102_+\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.04529e-46
NZ_CP022263.1\|WP_089111415.1\|448528_449836_+\|acyl-CoA-synthetase	gnl\|CDD\|223442	COG0365, Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism].	1.13778e-43
NZ_CP022263.1\|WP_089111405.1\|421813_422389_+\|type-VI-secretion-system-associated-protein-TagF	gnl\|CDD\|132416	TIGR03373, VI_minor_4, type VI secretion-associated protein, BMA_A0400 family. Members of this protein family are found exclusively, although not universally, in bacterial species that possess a type VI secretion system. Genes are found in type VI secretion-associated gene clusters. The specific function is unknown. This model represents the rather well-conserved amino-terminal domain of a protein family in which carboxy-terminal regions, when present, show little conservation. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	7.23017e-44
NZ_CP022263.1\|WP_089113453.1\|437177_438221_+\|type-VI-secretion-system-protein-TssA	gnl\|CDD\|274544	TIGR03363, VI_chp_8, type VI secretion-associated protein, ImpA family. This protein family is one of two related families in type VI secretion systems that contain an ImpA-related N-terminal domain (pfam06812).	2.87268e-101
NZ_CP022263.1\|WP_089111409.1\|427256_428933_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	3.40841e-61

>NZ_CP022263.1|WP_089111409.1|427256_428933_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MTCLAAAVSACLLLAAPAWAQSPTDATAAAQSAAAVPAMKDRTDAVTLQVRGFRVRDVGHYPEAGIDPARMQAVADAAFAELAQGQPVVALRFDQLQAVADAVTRAYRQAGFIVSTAYLPAQTPGPDQLIEIRVLEGRIGQISVQGAARYRGNALSAPLRQLQGRPLRKQDVDTALLYARDLPGVSVSSVLQPGQKEGETDVVLVASEAARPYVITLGGNNYGTELTGRYRAQAGITWNSPLGLGDVFAANYAYSLAPRQSQIGALSYGLPIGRVSGLSAVIGASRSELEVRNGVFARLGLKGPTSIVYTGADWKFINSEVLQLQGSARYLREQSKLSALGMQLSDQQFDVAELGLSLRRTDLRWRGVDLLQVSVRQSLRDRSAPVDQISPGRDSYFTIARLAYTRLQYLTRTQRLYFKFNGQYSDDTLTPMEQFAVGGPDSVRAYPVSDALGYRGYYTALEYHIDAPGFADAASPFNGRPWRELLELDVFADHARVFAANGRLAPASFDAAGVGLTFRLPQYANFEWRISAALPTGARDASDGRDDARIYTRFGFTF
>NZ_CP022263.1|WP_089111408.1|426798_427260_+|hypothetical-protein
MSAAPPSPTAAAAHPANAQLQALALAHQQGQLDREQYRSRRRRVLDAARQTQGVTLRNAVPSSSDARPSPLLGYRVTRKLRSQVVAVFAIVMFIAIILLTLHKCTSGFDRRSAKGEVRHANYCAVATVAPVYAVGHVGHAQQRMVSGEMDVCV
>NZ_CP022263.1|WP_089111407.1|423106_426802_+|protein-kinase
MHEDTATVTELVTAMRRGALDLNAVLAALGRRAAVPEAEYRAGVETLWTLQRQHLLDDATVTTLVSRLDALRDRAPALAPSAAQEPTPTPTVVDDDATVVMPRPGPARMAENDITRVQPAQPVSGDAPSLTSLGLGTHPNLGTQTGTGTGTGTAGTASLSSWQHLAEAAGGDHAGVGSLLKGRFQLERELGRGGMGVVYLARDERKVEARDRDPWLAVKVLSDEFRRHPDALVALQREARRSQKLAHDNIVRVYDFDKDRTLVFMTMEYIDGCDLKTLIREQAYNGMPLRQAWPLIDGMGRALMRAHAAGIVHSDFKPGNVMVTRDGVAKVFDFGIARAGKHAAEVAGEQTVFDAATLGALTPAYASLEMIRGRAPTPADDLYALGCVCFELLTGKHPFDKLSAEVALREGRRPPPVPGLTRRQYATLCTAVAFPAAQRLTRVDQLLDGLRQVPLRERALPLIGYGATALALVGVGGWGASRYLHQRHLDEVIARFGAQDPQQYRDQTQAMQALSSLSADDRRRVLMDRSDLIEDFLLRRLDALWNPANGRDDYRGALQVFALRDRLRLYSPSLDARRQAIEREKNQRLNALDTTLNRQLDAGLLFRTQADNALATLDQVRRIDPGSSLLRHSALEVRLDAAIAEAVAAGQLSTARTEVDQARAAFPDSLRLQLRSAEVGVAEQQARRTPVAAAPRDADSARTALAADLANPSTDPAWRARIDAGLAALPAAERSSQGSALAEAISTAVAAQSDPAQLAGAQALVDFGLRLAPQSASLLAQRTRLQTLEQQFEQALARESAEAELAARIESLRRAAAANDLGKTRDALARIRTLQPEHPLLRSEGPQLLSQVYRNTAGDAFAQGRYAQAADLLRQGLQTLGQRAELRSAQTRYAVAAAVMTAGALPPSERQQLAGRLQTLYRTDATALAQLEAQMKAAGQLPEGSLSARLQRAPAADAPADDSVPPASATGTAAPAAGAKPARDKSAARPAAATPITARDPAAAAALPANVDDADSLPPVPTGPDPCAGLAGRGAACFDTLGQTRAPMLVVIPAIAGGKPYALSRGEVAVADFNLFCQATGRCTAQAAATPELARAPVRNISLTQARAYLRWLTIGSGGWRYRLPSDAEWLHAAQAASNWRQAEDSNCVPPNASAGDAARAPVSARGRDANPWGLINLTGNVWEWVSTGTGVQARGGSFSSYWSDCTVQASRADNGSAQPDVGLRLLRELP
>NZ_CP022263.1|WP_089111406.1|422385_423102_+|serine/threonine-protein-phosphatase
MNAPYQSAGHTETGKVRRLNEDALLLREDAGLWVVADGLGGHSAGDYASQLLVQRLRALVRPADLCDFLDAIDDTLAQINRELLQVARERRVDMIATTVVVLVHDPDFMLCGWVGDSRIYAQHGGPLRQLTRDHVHGVRDDLTQFGSAHASAAAAGVLTRAVGAQEPLFVDWVLTPSLPGTQFLLCSDGINKEIPDPELDAECHRFGDPRALLARLFELAMGRAARDNVTAVVVRLQE
>NZ_CP022263.1|WP_089111405.1|421813_422389_+|type-VI-secretion-system-associated-protein-TagF
MSMPENEPLGFHGKLPGVADFVQRRLPASFVQPWDLHFASCLDTVRQQLGQHWPGAYRNSGLRAFALGPGVCGAQAWAGMLGPGEDRVGRCFPLTVAMPLPHMCLPPAAWFGAVAACLGRSLRARTDAAGFDAALLALGVPAAPSSTYAPVHGKSWWWRLGAAAQAMHGLPTAETYLDWLLAEQDITEVTR
>NZ_CP022263.1|WP_089111404.1|418286_421817_+|type-VI-secretion-system-membrane-subunit-TssM
MTMKTMLSKLSATVVVGLLALCLLSVLLWVGGPYVALAGWSPLSSVAARLLAIVLLLVVWVGVLTLRRWRRQVRAATLSSALAAPGRDDDRELRSGQERAQLQARFQQAIQLLRKRRGGADLYTLPWYALIGPPGSGKSTLLQHSGLQFPLAARMGDAALRGVGGTRDCEWWFTDEAVFLDTAGRYTTQDSDQAVDAGAWRDFLRLLRRHRPRRPLNGVLVTMSMSDLLLLDDAERDTHMQAIRRRLDELAEQLQASVPVYLIFTKCDLIGGFGEFFDDLTPAQRNQVWGMTFTLAQTLDGHAARRFADEFGVLQQQLSARLFERLNLERDRLRRAAILSFPQQVAALGERARQCVEGTFAGNAYGPAPLLRGVYFTSGTQDGTPIDRMMGAVARTFGLEEARVQAPGAQRRTFFVERLLREVVLRESGLANTPPAQQRRRVWLQAAAYAGVALLTGAVLAGLGLSYLGNRAYLQQVRAALDARPAVPDPNAATRMPEYVARTLQQADATQAVVKVAQQYHAGAPWALRMGLFQGQALGEQVQAGYLRQLNATLLPALAVRLRTGLVDNAQAPQALYYTLKGYLMLGQPQHLDPAQLSALAAIEAEKLFPREPALQQALGAHLQAVLESPTHVRALSLDNQRIAQARASLRAADLSTLIYGNLLLTPPDGTPLRLDKALGLLADTFVRRSGTALSTPVPALYTQPVFAALQREGIGQAVERFGYDDWVFGGTALDASAKATLVREVGQRYTADYIRFWDALLADLQLRPSADLAGASATAAKLAGPSSPLRLLLGVVGEHTQAMERPPPADPAQRALAAAASSAGAKANAAAAKLPGGAAMSAALATPADGAATATPAPGAAISEHFLALNALAAGAPGSTPLDHLLSVLDQLGKQLLVISQGGGDAAAANAQLALARQEMAQLPPPVTDWLQSLAGSSATLMTQGARAALDAQVRQSVGEVCTDFVRGRYPFDPEAQVEIPLQNFGELFGSGGRLETLYTGTVEPLLDTQSPQWRWKDGPDAVIGAPGLPVQLQLAQRIRQKYFRGGPTPQIGFTVLAPTLGEGVARLTLDIEGQRYDYQPGAAQSMPMIWPGPVPGHVSIAAFGADGVALGTLDYQGDWALFRALQAGHLENPSDLRFVASFALGGHDVQVPLRAGNLRHPFLDSDVQHFVCGG
>NZ_CP022263.1|WP_089111403.1|417009_418290_+|type-VI-secretion-system-protein-TssL
MGDPELSMRRPVADLAPAYAAPLPAAEGTGVPSEDTDISELLGRSVNPLVQAATPLLLLAVQLRHSAQSPDVARLREQVMAQVRRFEHRARDGGAPVEAVTAARYVLCALLDEAVLNAPWGERSGWSQKTLLVTFHSESYGGAKFFQILERLCADVPRHLDLIELMYLCLALGFVGRYQIEAGGIATLAAIQEDVYRRIRAARGPAPESLAPRWRGVDDRRRLGRYLPVWAAALLGLSVLVVAFVWLQARLNSLSAPISAQAAQWGLAPATPPDAAPVPPPPVRLKQLLSAQERAGLLRVDEQADGQTRVRLSSAAMFASGGVEVEPQQRGVIAQIAAAIEQLPGRVIVVGHTDDVPVRSLRFQDNYALSAARAQALAQVLQAQLSTPGRVEAIGAGDSQPIAQPVQLPANRARNRRVEILFQPGE
>NZ_CP022263.1|WP_089113452.1|415693_417028_+|type-VI-secretion-system-baseplate-subunit-TssK
MQNNKVVWSEGLFLRPQHLQQQERYLERYVDLRAARLRPHAWGVSELEWEADLLAVGKLGLRHARGVFADGTPFAMPGDDPLPVALEVEPNCRDQIVYLTVPLRVPAQPELGRPESPADQLFRYRVRETESNDASGSTSEAVLMEVGGLSTRLLPHSQPLEGLDRIAVARIIETRADRQVVLDPHFIPSAMVCQAAPRLTMFLTELVGLLHQRGEALASRVTLTDRGGAADIADFLLLQLVNRWQPQMAHWAAAPLAHPEELFRALVALAGELSTFTAAGKRPPAWPAYRHESQQDSFEPVIAALRSSLSAVLEQTATPLPIQARKFGVWVAMVPDPGLLDSAAFVLAAKADMPSEELRRQLPAHAKIGPVERIRDLVNLQLPGIVATPMPVAPRQIPYHAGYLYFEFDKSAALWRTLKTSGGIAFHFGSEFAGLDLQLWAIRS
>NZ_CP022263.1|WP_089111402.1|414300_415191_+|aldo/keto-reductase-family-oxidoreductase
MNSGKLLGGRLTLPGTTLGIKRMGYGTMQLPGPHVWGPPRDKASALSVLREAIALGANHIDTAQFYGPDVSNALIREALHPYRSDLVIVTKIGFSRGPNASWNIDVSPASLRRQVHENLQSLGLETLDVVNVRLGTAMDTDERSIAEPVACLAELQREGLVRHIGLSNVTARQFEQAQTLVNIVCVQNQYNLVKRDDDAFIEMLAQQGVAYVPFFPLGGFSPLQSELLSGVARQVGATPKQVALAWLLQRSPNILVIAGTSSVTHLRENFASAKLSLSTEQVATLDGIAAEASGAQ
>NZ_CP022263.1|WP_082332431.1|413168_414050_-|LysR-family-transcriptional-regulator
MEAFVRVARAGGFREAAKSAGVSASTYSDAIKRMEASLGVRLFNRTTRSVVLTDAGNALLARIAPALLELENAREVVSAFRDTPTGTLRLNVPVSAARLVLPRILPAFMAAYPDITLEILTEESFVDVIAARCDAGIRYGERLQQDMVAIPIGPRVQRIATAAAPGYLDRRGRPTHPRQLVAHDCIRGRFPSGVIAEWEFERDGEVVTIVPQGQLLVEIGGGIELAIQAAIAGSGILHLFEQWLQPQFDAGALEPILRPWWQPFQGPYLYYPNRTLTPPALRAFIEFVKTLPD
>NZ_CP022263.1|WP_089113453.1|437177_438221_+|type-VI-secretion-system-protein-TssA
MQDDSSLETLLTPLGDDAPAGPDLEYDPEFLRLERESAVRAERALGESVIAAEEPDWDKVQALALDLCRRSRDLRVAGRLGAAWLRLRGLPGWADALALIHGLLERHWDSVHPQLDADDDNDPTSRINALVGLSDPMGLLGALRTTAFVQSPRLGRFSLRDLRVANGSIRLPDGQSGPSLAEIEACCQDCTPETLATSAQAITEALRQARAIDALLSERVGAAAPDLRPLLTDLRDLERFVLPHWQARQGILAVNEDGEQAAGEGHAVATATNATRRNDKIAGPDDVKRRLEEICAYYARHEPSSPVPMLLRRAQRLVGADFLALMKELAPAGIDELQRVTGPLEDS
>NZ_CP022263.1|WP_089111411.1|438530_438821_-|DUF2782-domain-containing-protein
MNKARLLLLPLLLLGGCATSGGDRAGGDIPAGADVTSKTMGNGDKVDEYRVNGQLEMVRVTPARGAPYFLYDRDHDGHTDAERDKVNKVYWQLYSW
>NZ_CP022263.1|WP_089111412.1|438897_441702_+|DNA-polymerase-I
MSRLVLIDGSSYLYRAFHALPPLTNAQGEPTGALFGVVNMLRATLKERPAYIAFVVDAPGKTFRDDLYADYKANRPSMPDDLRAQVQPMCDIVHALGIDILRIDGVEADDVIGTLALQGAADGLAVTISTGDKDFAQLVRPGIELVNTMSGSRMDSDAAVIAKFGVRPEQIVDLLALMGDTVDNVPGVEKCGPKTAAKWLAEYDSLDGVIANADKIKGKIGDNLRAALPRLPLNRALVTIKTDVTLASGPRALDLREPNAEALAVLYTRYGFTQALRELGGAAAAQAGLLAEPVALGAAAATARTEPGRARGTGFVSGPVNAAVDLDPSLSAPGQYDTILTQEQLDSWIARLRAAGQFAFDTETDSLDPLQADLIGLSVAAEPGQAAYLPFGHNFPGAPVQLDRTQALAQLAPLLTDPAVRKLGQHGKYDLHVMRRHGVELAGYADDTLLESFVLNSGSARHDMDSLAKRYLGYDTVKYEDVCGKGAKQIPFAQISLEDATRYAAEDADITLRLHRVLGPRLTSEPGLERVYRDIEMPLVDVLARIEANGVCVDAAELRRQSADLSKRMLAAQQKATELAGRTFNLDSPKQLQALLFDELKLPAVVKTPKGQPSTNEEALEAIADQHELPRVILEYRGLTKLRSTYTDKLPEMIHPQSGRVHTSYHQAGAATGRLSSSDPNLQNIPIRTEDGRRIRRAFVAPPGRKLIACDYSQIELRIMAHLSGDPGLVGAFESGADVHRATAAEVFGRTIDTVSADERRAAKAINFGLMYGMSAFGLARQLGIGRGEAQDYIALYFSRYPGVRDFMETTRQQARDKGYVETVFGRRLYLDFINAGSQGQRAGAERAAINAPMQGTAADIIKRAMVNVDGWIADHAQRAKMILQVHDELVFEADVDFVDTLLSEVTTRMAGAAELRVPLVVDSGVGDNWDQAH
>NZ_CP022263.1|WP_022560294.1|442555_443455_-|oxygen-dependent-coproporphyrinogen-oxidase
MNEFDRVRDYLTDLQDRICAAVEAADGKARFAEDLWKREEGGGGRTRILRDGAVFEQAGIGFSDVSGTRLPPSASAHRPELAGATWRACGVSLVFHPHNPSIPTTHMNVRYFRAERDGEVVAAWFGGGFDLTPFYPFDEDVQHWHRVAQALCVPFGQERYAAHKRWCDEYFFLRHRNETRGVGGLFFDDLGQDFERDFAYQRAVGDGFLDAYLPIVERRKDTPYGEREREFQLYRRGRYVEFNLVYDRGTLFGLQSGGRAESILMSLPPRVRWEYGFTPEPGSAEARLADYLIPRDWLG
>NZ_CP022263.1|WP_089111414.1|443891_444458_-|hypothetical-protein
MSTVQPASARQRGGFVTPLAWVSLLLGVVSVLANLVQIAMISLTPGAASLGLPAGITLPHSWQWLIDHALSLSVAGAVLSAAFCWLSWALLQRREWARLGFVAVLLGTGVLNFGGLALIGPLFDGVQTLLPADVLQSPEWPQMQARLQATQQMALVLTGLGALAIGCVHAVLAWRLCTPAVRAEFSQP
>NZ_CP022263.1|WP_089113454.1|444454_445171_-|hypothetical-protein
MGLWDRLFGRKSTAANTPRTAPTAAPAAAADASEAGAEIDPALQPSLSAFQRGDHVGAYNAAQTQLHLGADAQRLCALSLSALDRYREAYPYWLALYELEPSAHNALQLATTSVMCNEIAQGEQWLLTFDDLNAQERSTSPATARTSFLTALTRADHGAHALPHLEWLREAYAGMSITDSHFLYVRGLPFLEAFLERSTPLLRQCLPADAVPEWYAQLQPALDPPGQAMVAAHIASLQ
>NZ_CP022263.1|WP_042676010.1|445561_447922_-|S9-family-peptidase
MLPLTLLLVATAAHAQSAAPLTIEQAMADPDWIGPSVDQAWWQWDGKQVQYLLKRDGSPVRDTYRQGTGGGTAERVADTARAGLDAANPSYDATRQRMLFARNGDIFLRDLRTGALTQLTRSNEIESRPQFASDGGAIWRAGNNWYHWRADGGTAQVAVVKAERDPNAAPKADVLREQQLATLATLRRDKEQRDALRTQEDAWRRADATRAAAPVYLGDEVEIVDSALSPDGRHLLVVTQAKSADEGQAGKMPKYVTESGYEEFQEVRTRVGRNAPAAHALWLVDVGAGTAKTLSFDPLPGISTDPLAALRKTAKRDALKGNRAVRVESDGDGSGPAVHWSDDGRNVAVEIRAVDNKDRWIASVDLDNARLQPRHRLSDSAWINWDFNDFGWLPDNRTLWLLSEESGYSQLYTVEGDGKPRQRTRGKWEVSMPVPSADGSGMFFLCNQKWPGDYEVCKLDLRNDQLTEITALNGVEGYSLSPNGQQLLVRYSGSYLPTQLAVVPAAGGQATVLTDTRTPAFKAQPWIAPQYVQVPSKHGAGTVWGKYYGPKTPEPGKQYPIVMFVHGAGYLQNVSERYTPYFREQMFHNLLVQQGYIVLDLDYRASEGYGRDWRTAIYRNMGHPELEDYLDGLDWLVATKQGDRARVGIYGGSYGGFMTYMALFRSPGTFKAGAALRPVGDWMQYNHEYTSNILNTPELDPEAYKTSSPINYAQGLRDHLLIAHGMIDDNVFFKDSVDMTQKLMELHKDNWQVAPYPLERHGFTRADSWLDEYKRILKLFNEQVKP
>NZ_CP022263.1|WP_089111415.1|448528_449836_+|acyl-CoA-synthetase
MAVGAPARPLAWRAGQSVDLATFIAHVHGLAQQLPEGSHAVNLCEDRYRFMVAFYACALRGQVSLLPSSRAPAVVGEVQARYADTYCLGDLTLELAPPRYWQLPAELPQAQGPIPQLADDALVAIGFTSGSTGSPQPNPKTWGSFLTSTRQDLVALQSLWTHTDAVPHVVATVPPQHMYGMELSVLLPMVTTLAVHAGRPFFPDDVARALADIPAPRVLVTTPVHLRALVESGVALPPLAGIVSATAPLAPEIAAAAEARFGGEVREMFGSTETCVFAVRRTALEAAWTPLPGVRLETQAAGTLVHAPHLATPVLLADMMDVADDGRFRVRGRQADLLEIAGKRASLADLTRRLLAIPGVIDGTIVQLAPDPGQAVGRIAALVVAPTLDEAQVLAALRVSVDPVFLPRRLRKLAALPRNETGKLPRDVVLGLLNG
>NZ_CP022263.1|WP_007972212.1|449884_450229_-|hypothetical-protein
MLLLAIVLAASVPAAPQLLVGQSFETFATQTDSLCPGRQARSITPGDLDFAQETFEAQLRPRTRTRLEAANTAATRCADRNGLSCQVEATLEALQQTRLLARFSRYVCSHPSPS
>NZ_CP022263.1|WP_167382231.1|450428_451436_-|pteridine-dependent-deoxygenase
MTASQAQTTHAVRHPRLQVDYVDQTDPAVLLTDPQVLAVFGFGDAAPRLHDPRYLHVPLQPYQASVLEVWRTDAPVSSGRDGNIAWSSDGHLQFGVIEIDEQDVDIEEAAARAYAEITAFVSNSQTPRLLRIWNYLDAITLGSGDRERYRQFCVGRARGLGAFDTAQLPAATAVGRCDAERIIQIYWLAAANAGTPLENPRQVSAYHYPRQYGPQSPSFARAMLPPAGSDMPLLLSGTAAVVGHASMHTGQLLAQLEETFANFDALLGVARQQAPALPAQFGAGTRLKVYVREREDLPRVAQALDARFGDAVPRLLLHAVICRDELAVEIDGVHG

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Crispr_ID: NZ_CP022263_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022263_4

3298288-3298373

Orphan

Consensus_repeat	Method
GTTGATGTCGTTGCCGGCGCTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022263_4

>merge|NZ_CP022263|4|3298288-3298373|CRISPRCasFinder
GTTGATGTCGTTGCCGGCGCTGATCCCCAAGCCTTTGCCTGCATCGAGCTTTGCGGCGACCAGGTTGACGTCGTTGCCGGCGCTGA

>NZ_CP022263|4|4|3298288-3298373|CRISPRCasFinder
GTTGATGTCGTTGCCGGCGCTGA	TCCCCAAGCCTTTGCCTGCATCGAGCTTTGCGGCGACCAG
GTTGACGTCGTTGCCGGCGCTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_089113555.1\|3285262_3286567_-\|threonine-synthase	unknown	unknown	gnl\|CDD\|236418
NZ_CP022263.1\|WP_089112539.1\|3284418_3285162_-\|murein-L,D-transpeptidase-catalytic-domain-family-protein	unknown	unknown	gnl\|CDD\|379310
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	unknown	unknown	gnl\|CDD\|274868
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP022263.1\|WP_042675108.1\|3286728_3287043_+\|EthD-family-reductase	unknown	unknown	gnl\|CDD\|131173
NZ_CP022263.1\|WP_089112541.1\|3293194_3293446_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089112545.1\|3305479_3306391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP022263.1\|WP_089112542.1\|3293752_3294361_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_042675106.1\|3282051_3283464_-\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|223202
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP022263.1\|WP_167382306.1\|3283709_3284333_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|236494
NZ_CP022263.1\|WP_089112547.1\|3308450_3321557_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_157768141.1\|3306391_3306763_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	9.46627e-33
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	4.41203e-94
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	5.43044e-37
NZ_CP022263.1\|WP_089113555.1\|3285262_3286567_-\|threonine-synthase	gnl\|CDD\|236418	PRK09225, PRK09225, threonine synthase; Validated.	0
NZ_CP022263.1\|WP_089112539.1\|3284418_3285162_-\|murein-L,D-transpeptidase-catalytic-domain-family-protein	gnl\|CDD\|379310	pfam13645, YkuD_2, L,D-transpeptidase catalytic domain. This family is related to pfam03734.	3.79482e-96
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	2.21317e-53
NZ_CP022263.1\|WP_042675108.1\|3286728_3287043_+\|EthD-family-reductase	gnl\|CDD\|131173	TIGR02118, TIGR02118, conserved hypothetical protein. This model represents a small family of proteins of unknown function, each about 105 amino acids in length. Conserved sites in the multiple alignment include a pair of aromatic residues, a histidine, and an aspartate. [Hypothetical proteins, Conserved].	2.66662e-35
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	1.01835e-99
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	1.43976e-45
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	7.78695e-135
NZ_CP022263.1\|WP_042675106.1\|3282051_3283464_-\|histidine--tRNA-ligase	gnl\|CDD\|223202	COG0124, HisS, Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	3.07952e-148
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP022263.1\|WP_167382306.1\|3283709_3284333_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|236494	PRK09391, fixK, transcriptional regulator FixK; Provisional.	1.46458e-45
NZ_CP022263.1\|WP_089112547.1\|3308450_3321557_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	9.81689e-32

>NZ_CP022263.1|WP_089112542.1|3293752_3294361_-|hypothetical-protein
MKLNGSVFDDLYSGEKSICFFVHHGKCYWVLDHKYNFSLDAERDFKAHLDKGNISKEQYALACENFRGGVLRLNSESFLKYLELNSDVIVSRVDLEAVLNFDGIGNVLSLLNAAEKYFLSGVDLSAYDFQAAGIFSSRLPMFYVNFDREIYMHLDHGRFHEDLVYPGWVAKVFDFNFLIPEKEKYWINGGDCWKIRFIQSGF
>NZ_CP022263.1|WP_089112541.1|3293194_3293446_-|hypothetical-protein
MVGRANGGASSIQVATGTNGTAGAQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTNVQTTAAAVSSPVKQTLQK
>NZ_CP022263.1|WP_089112540.1|3291310_3291811_-|tryptophan-rich-sensory-protein
MTQHRLNTSQWFGLLGWLLLCYAVAALGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVVQLALNGLWSWLFFAWHLGAWAFADIVALWLVLAATIGAFAKKQTLAAWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP022263.1|WP_007963907.1|3288133_3290641_-|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP022263.1|WP_167382366.1|3287117_3288092_-|homoserine-kinase
MVQAQAQGSDHASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHNALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG
>NZ_CP022263.1|WP_042675108.1|3286728_3287043_+|EthD-family-reductase
MIKVSVMYPYRDGARFDHAYYRDQHMPLVSARMGAACLKYTVDKGISGGEAGSPPAFIGMCHIFCGSVETFNAGFGPHAQEILADIANYTDLTPVMQISEVVVD
>NZ_CP022263.1|WP_089113555.1|3285262_3286567_-|threonine-synthase
MFISTRGGAPAASLSQAIAAGLAPDGGLYVPQTLPPARTLVAGAGLADTATALLQPFFEGDALAAELPAICAEAFDFPAPLVALGTPGDYALELFHGPTAAFKDFGARFLAACLTRLRRAEDRPLTILVATSGDTGAAVAAAFHRQPGLRVVVLYPDGRVSPRQAHQLGCFGDNIQALRVAGSFDDCQAMVKQALNDAALQTQVPLSSANSISLGRLLPQMSYYAHAALEHHAASGSVLNLVVPTGNLGNALAAIIARALGVPLGRIALASNANHVLPDYFAGDAYVPQPSVATLANAMDVGAPSNFERLRWLYNGDDAALREEFRALSVDDAAIRHTVQQRFARYGEVHCPHTATAVHVLEQLRAEGAEGGTGDWAVAATAHPAKFEGVVEPLIGRAVEVPPALAALLQRPAQAEALAPDYAALRQRLLADAT
>NZ_CP022263.1|WP_089112539.1|3284418_3285162_-|murein-L,D-transpeptidase-catalytic-domain-family-protein
MSDRMIAVAAVLCGWAAAGAANAADALSASPVPPLGAPRVGLVEALARQAPSLDRQVLALATEALQCARQRQQVGAERVLSVIDYSRPSTERRLWVFDLDKQRLLFREWVAHGRNTGENLAAKFSNNDGSFQSSLGAFTAQESYTGHNGYSLRLKGLEPGFNDHARDRAIVIHGAPYVSEAIIRTQGRLGRSLGCPAVRPAVAKQLIDTLRDGAFVFAYYPDRAWLRQSRLLSGGCSSAAARAVAGR
>NZ_CP022263.1|WP_167382306.1|3283709_3284333_+|helix-turn-helix-domain-containing-protein
MDTLDQVTHAAAYAPGSTLVRAGETRHNVYTVTSGALRMVRTLADGRRQITGFVLPGDYVGLTETAQHRHDIEAIVDSRVCRTPMAQMRQLRERYPQLERKLLQRASMELAAAQDTGLLLARLHPSERLAHFLLRLAARSTQPGASGDTVALPMSRSDIADHLGLTVETVSRTFTKLRQQQLIALPQLHLVQILDYAALRRLAGDAV
>NZ_CP022263.1|WP_042675106.1|3282051_3283464_-|histidine--tRNA-ligase
MIKPRTPPGIMELLPREQIAFQRMLDVIRRNYERFGFLPVETPVFELSDVLLTKSGGETERQVYFVQSTGALANAAAAADEGAENGGLPELALRFDLTVPLARYVAEHEHDLSFPFRRYQMQRVYRGERAQRGRFREFYQCDIDVIGKDALSIRYDAEVLAVIHAVFAELGIGDFKVQLNNRKLLRGFFESLGVAEGELQLAVLREVDKIDKRGADYVRDTLVGEGFGIPAEQVARILAFVAVRSEGHADALAQLQALEGSVGASATLGEGIAELREVLELVKALGVPESAYCLNFSIARGLDYYTGTVYETTLTDHPQIGSICSGGRYESLASHYTKSKLPGVGISIGLTRLFWQLREAGLIQGIAESSVQAMVALMDETRLDDALDIARRLRIGGINTEVQMEPKKVGKQFQYAARAGIRFVVLAGDDELARGVVAVKDLVREQQFDVARDELASTLLVELEQAKAMP
>NZ_CP022263.1|WP_089112544.1|3300206_3305231_-|ParB-N-terminal-domain-containing-protein
MGRAATSLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQTVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALAAGNNLVSEATKAINGVGILSGITASNTLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDAVSVTTGKDLIVSAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGKVATRTNISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVDTSDTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASAATKEGGITLAAGNDVNLLADSEQHDAVQDMTKKKKGTFSSKTTTTHDEWHDNVAVTTTLSGDTVQIAAGNDLLSQGAQVASTGDLVLAAGNNLTLDTVQNTHSEEHEKTVKKSGLYGGGGFSVALGVTKKTDGLDVTEVTNTGSLVGSTDGSVTMTAGNKVSITGSDVLSATSTTIVGKEVTIAAAENTVDTVQTSKQQSAGLTLGLTGAAVEAAQAAYMATKRGSEVEDDRLKALYAAKTAYALSDAVSAYQAPPTSGGQDAVSLKIALGASSASSKTTTHDETTGGSRILSDGNVTIAATDGDLNVIGSQINGQNVTLAAANNLNLLSNKETNTSKSENKNGGGEIGVSVGTTTGFYVSAYAGKGSAKGNSELHTESVVTAKDTLTVASGNDTTIKGAQAIGDTVLAKIGGDLLIQSEQDTEDYKSKQQQAGVKLVYGVSGSSASYSQQKVNSSYTSVNEQSGIQAGNGGFDISVGGNTHLIGGAIASTADALLNHLSTGSLTVEDLQNKAEYKSGGFGVGTGDWQSVAAGAALSLARNQTGSSGSTTKSDIAAGSVEVRNGDSTALAGLDRSATELQQSGLKQVFDEKKVAEQQELAQVAGEVAFRSAKELISYKREQAAADAEQAMADLEAANGDPDATATAKARLLAANDQLAKWNDAGAAKQITQVTAGALAAAVSGGNVLSAAGGVLMNEKLLPKFADVLQKGGIQPGSGAEATLMGGLGALLGAAGGLLGGDVQAGAASGNAVQTYGYYDYREGRAQRLAMAAEALKNVGITDPNDVAGVNALLDNCVKLGCDPDKLVLLLKSPDAASTLRELAQPESVAFQRYGKGFNELDEQQRRDVINHIPTGVVSVGAVGSAHADGTAASSSEGADNSQGIAGSQQSQDENLRLKGATVVSNLAIAGGKKVEQFKNWLGEDNAETAALILMAAAGGPVKTLGSTLWAATPMAGYLQEKKEQYLVNPLTPLIGTNAFGAVTDSDQQAVQPASHATSSMLVDTLLSSLGVMGTKAGAIGIIKSSDGFSGAVKDAEKNISPPSAQELTAAITQDGSEIITRNVDPKILIGRQGRDEISGSQVKRYTKDMKANGYDVNHPIDVAKVDGKLIIIDGHHRALAAPRAGIKEVPVNVHNVTREEADQLMREAAEARGGR
>NZ_CP022263.1|WP_089112545.1|3305479_3306391_-|hypothetical-protein
MKNLSGRSDRPWELMGVFKDEFILEFNGGIYSDVDGICDKYNFLHERDGAGYRNVDYSGLLLNGKSWIIEPLRLLQPNSYQAFQEAAEPLLLGVMLIEDLRNPGGPPMVRPILFLEVHGRMVEVFATFPSSTYEDGNDCFGSLLSLPDGLAKSWLWRTDGWRIPGSVGEGPMTNRQLIGHPSSRWRDADTYLDSLGKGWKKKYLPKIKELFPDAVTNINGVKRIKFRCFLDTRPVGVGGPEGDQFFVCSTRQDQVVYHVHEGNVENLRVLRNPEDAIDRYCAHVLRRKPGQFDFSDWSEPFRP
>NZ_CP022263.1|WP_157768141.1|3306391_3306763_-|hypothetical-protein
MNAKNELTWINPLTGVKEAVPATAKIHVDHVLPQNAIRQIDGFDSLPKSVQNEIMKDPANLQPMIKSANCSKGCKVEAEGAGWMTWNGKPVSEKYKMYLEEAQQDFRTKVSKIIDDNNALKGK
>NZ_CP022263.1|WP_089111250.1|3307379_3308360_+|IS5-family-transposase
MQLTFGDAEGLGKRKQTRREIFLAEMEQVVPWQQLLWLIAPHYPVSGRPGRQPYALATMLRIHLLQQWYALSDPAMEEALHEIPTLRRFAQLGGLDDIPDETTILNFRRLLETHGLAARMLEAVNAHLARKGQSLRSGTIVDATLIAAPSSTKNADHARDPEMHQTRKGNQWYFGMKAHIGVDEFSGLVHHVHCTAANVADVTVMHTLLHGKEDSVFGDSGYTGADKREELQDCEAAFFIAARPSTIQAIANKCERAQEQRWERFKASVRAKVEHPFRVIKRQFGYTKVRYRGLAKNTAQVLTLFALSNLWMKRKQLLPAMGSVRL
>NZ_CP022263.1|WP_089112547.1|3308450_3321557_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MDNEAMRVRGYLAEQGKRALALLLCCTTTWTSFPAWAQVAPTANPAGQTPGQQVAANGVPVVEIVAPNARGISHNRYSNFNVGPNGLILNNSAQISKTELGGYVAGNNNLQRSGAASLILNEVTSASSRLQGYTEIAGAKAQLVIANPNGISCDGCGFLNTSRVTLTTGTPNLGSDGALNGFSITGGALSIGRNGLDAFNVDRLDLLSRQLSVDGSVWTRELVAAAGAGRVNYDGMLLDVLPGADGAAPAIGIDVAQLGGMYAERIRLIATEAGVGVVSRGTLAAQSGDLQIDSAGQLSLSGTTVARDAVNVRATGALDQRGVLGSQQGDVYLRAANMTLAGDLVAAGALDAQAGGVVNHGGRSSAGSIRLFGPQLNADGSLHTNGALDLGADGLLSSSGVAYGGAGANLRAAQIALSGTLQSGAAIALNATTIDALGTLDAATALQFKGNGDVRLAGLAQAGQGADVQAGGRLELQGQLIAADALALNAASTDIAQRAAVSAGNDLDLRSAGAVNNAGSAYAGRDLRLQAASVTTAGSLSAARDAQLSVEGQLLNSGTIVAGDALAVNAAQLASSGDIGSQRGDATLRSRGNLRLSGNTVAGGALALDAASSAQVSGTVNAASVNLRSGGDAILSGTLQSTRGALTVAAASELANDAVLRSASALDLQADGALRQRGQLHSNGGVQLRGGSVAHNGLIDAGGDLRIASAGALALDGTVQSAGSTTLQAAGALDNSAKVVTAGPLQMDASSLHNAQGAAFSSGADAQLRIGGTLENAGSVYAANALQISADSLTQNGSVGSGNTLSATVAGTFDNAGNVVARDGLQIDAGDLRSSGQLGSEAAGVVLGSQSDIALQGVVAATTTLQANAAGDLQQSGSLKAQSVALRAGRDLAASGTLQSASTLDLQAQRDLTFTAQGQAGGDIGMRAATLTTSQDAVLQGAAAIALDSGTIHSRGKLDAGSDLRVHSLGDLTLAGIAQGSGDVELTATGALTNAAQVFAGRTLTAQAQSLENTAAGVLAGDGNVALTAAAQLRNAGRVQAAGDLQMTAASLDQSGSASAGKTLRGTVAGTLDNRGNLIARDALQIDAGTLRSSGQLGSELASVALSSQGAMQLDGVVAAATALQASAGGDLQQAGSLKAQSIALQARQDLTANGSLQSASTLDLQSQCTLALNGQASSAADATLDGATITTSAVAVLQSGASITLAGDSIDSRGALDAANDLTLRSAGDLTLGGVAQAGRDIALTATGNLNNGAQVIAARDLSVQAASAANASDATLGAKRDLRVDVAGVLDNRGSLHGERGLSLTSGSLLQRGRVYSGDALSIASNGAFENAGQLVSGKELSITAGSIVSNGQLGSVTGALALTSQNAIALQGVVSAATTLQATAGGDLSQAGTLSAQTVALQAGRDLVAGGTLQSASTLDVQAQRTLSLNGQAQAGTDASLHSNSIVTGRDAVLKSGGAITLDGAAIDSRGTLDAGTDLVVRSTGDLALAGVAQANRDVVLSASGALGSASQVFAGRNLSLQAGSINNAAAGALAAAGGVTLATGALQNAGSLQSGGDLRITAASMDQSGTAVAGKALTATVTGTLDNRGSLIAKDAVLVEAGTLRSSGQLGSEASTVTLTSRGDMTLQGVVAAASTLHAAAGGDLHQAGSLKAQSIALQAGRDLTAAGTLQSASQLDLQAQRALNFNGQAVSAANANLRGAQIATGQAAVLQSGVAISLDGAAIDSRGALDAASDVNLRSTGDLAVAGVVQAERNVVLSAAGALTNAAQVVAGDGLTVTAASASNTATGVLLAQGDTTLSIAGLLDNAGVVRAGNQLSLNVGSLRQTGQAYGLQRLGVSASGAVDNRGDLIGGNALRVEAGQLSNSGQLGSERGDVALISRGDLQLNGRLASAGAFTAQADGALTQSGNLSAASTLDLRSKGDLTIAGQVAGQQLALVSDAVVRQQGTVSGTTVDVQGARIENAGQTTAAGNLSLRAGEIGITGTVGAGINADGSLGSGSTLSLVADGQFAASGTLLAGGNLTAQGSQLQLAGSTTRATGNVALATGGSLDHRGGNLLAGGTLTAQAGGNIDNGRLNNMGGQLQANQLSIDGGSLSNVGGALVQSGAGLTRVAIGGAIDNTAGTLASNGQDLTVTAASIENAQGRIEHAGAGTLSVTSRAAFGNSSGRILTQGQLTLGASGALNNQSGAIAAAGDAGVTAASLNNLAGSVSARTLNVQTSGAVDNRNGLLQASGGALTLRADSLSNAGGTVQAVANAGAGGGLRVELNRGLDNGNGTIGASTDAVITAENISSAGGNLQAGRDLSITARGQLDNHQGGKLSAGRDLSVAVAGALLNSGDQLDAGNTLTASGGLIDNTQGSIVSNGSGLTRLTTGGALTNTSGNLGGRGSVVIDAASIANTSGQLVAGGDLIANTNVLDNQGGSVYAGANFLLQRAGATLDNQSGRIKAEQSVRLNLQNLSNAGGQIGAGSVTGGVGDVLIDTVGFDGGGSILAQNLLDLTLRSDYTHRAGADLVSNGNFNLRVGGNLVNESTLKAARTLDITASSITNRAGANILSNDTRLNGGNVIDNAGSVSGNGALLLVANSVYNTGSIVGGNVSVNTGTLVNGADLGGATDNAAYGSALLGSTGNMNLIVRDQLLNRDARIFSLGNIAIGGAQDGGGTLVSRTGVVNNLSGSIEADGSILIAANQLNNRRRVVNTTSVSTDPGNDDVYSGGELIEGKAIRNIQGARAPYPYKGLAPGIYRNYQVIQQEQLSSASAEGRIAAGGNILLSGSVTNNASTIAAAGVFAANQRGLGGLSDGMIVGGEQLLNQALALNQTVRQSDVEHIVTAITNDCMQPVGQKVVCYYEEEDQRLSSSTVSSSYIALGASMTGNQGVSINGANISNGAVGSDGRSISGASLNGVGAQGGLNGRTTQSAVGVGGQAVVGRASGGAGSIRVATGTSGSAGTQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTHVQTTAASTGVTAGANETRTRVDPATIPVANIVGGGQTSLTQIDLPIGGLYRLSSGTGTDLNAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQKVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGNNLVSEAAKAINGIGILSGITASNSLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDVVSVSTGKDLIVAAGNDLQLHGVSINAGGSAALQAGNNLSLTPTTGLDGKVASRTSISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVETSNTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAATAATKDGGITLAAGNDVNLLAASEQHDAVQDMTKKKKGTFSSKTTTTHDEWHDNVAVTTTLSGDTVQIAAGNDLLSQGAQVASTGDVVLAAGNNLTLDTVQNTHSEEHEKTVKKSGLYGGGGFSVALGVTKKTDGLDVTEVTNTGSLVGSTDGAVTMTAGNKVAITGSDVLSTTSTTIVGKNVTIAAAENTVDTVQTSKQQSAGITLGLTGGAVDAAQAIYGAAKRGSEVEDDRLKALYAAKAGYAVSDTAGLVSNGLKGYDGQAVAGNMTKTGAAAADGAQGAANAAGVSLRLGIGASSSSSKTTTHEETTGGSRILSNGDITIAATGGDLNVIGSKIAGENVALAAANNLNLLSNKETNTTKSENKNAGGEIGISVGAVTGYYLSVSAGKGSAKGNSDLRTESVITANNTLTLVSGNDTTIQGAQAVGNKVLANVGGNLLIKSEQDTNEYKSKQQQASLTLATGSGSGGSYSQQKVNSSYTSVTEQSGIQAGNGGFDITVGGATKLVGGAIASAADASLNRLSTGSLTVEDLQNKAEYKTSGVSVAGGTGSSMASMAIGTGLSMLGNSSDSSSSTTKSDIAAGSIQIRNGDQSALAGLDRSATELQQSGLKEIFDQKKIEDQKELMGLAGEIGFRVAGDVASAMYQKAQLDLASAPDEASKAQALARLDAWSDGGTNKILLHGLTGAAIAALGGENVLQTAAGAAGAEAAKVAMSDYLVKNGVTDAATYNALMELGSAALGGIAGGQVGATTALAGDQFNRQLHPDEVTWIRQNAEAFALQEGIREGLNNDA
>NZ_CP022263.1|WP_089112548.1|3321627_3323328_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREDADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGDSHDLATRNEERGTRGNSLSYSLPWGWWTFALAASSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPVYGARVIYQF
>NZ_CP022263.1|WP_089112549.1|3324059_3326018_+|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPEYPDDAGLQRLGASLERQRGWQVHLSHAWGHSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDEWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGPAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDETRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQREQQLGLDLDFRWGGTP
>NZ_CP022263.1|WP_089112550.1|3325999_3327898_+|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRWRIETDLRHSRDAVVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQIDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQLPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP022263.1|WP_046832236.1|3327901_3329155_+|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP022263.1|WP_022559030.1|3329151_3329598_+|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVNADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR

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Crispr_ID: NZ_CP022263_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022263_3

3298072-3298161

Orphan

Consensus_repeat	Method
GTTGATGTCGTTGCCGGCGCTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022263_3

>merge|NZ_CP022263|3|3298072-3298161|CRISPRCasFinder
GTTGACGTCGTTGCCGGCGGCCAGGGTGATGCCGCCTTCCTTGGTGGCGACCGATGCGGCGGTAAGGGTGATGTCGTTGCCCGCCTGCAT

>NZ_CP022263|3|3|3298072-3298161|CRISPRCasFinder
GTTGACGTCGTTGCCGGCGGCCA	GGGTGATGCCGCCTTCCTTGGTGGCGACCGATGCGGCGGTAAG
GGTGATGTCGTTGCCCGCCTGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_089113555.1\|3285262_3286567_-\|threonine-synthase	unknown	unknown	gnl\|CDD\|236418
NZ_CP022263.1\|WP_089112539.1\|3284418_3285162_-\|murein-L,D-transpeptidase-catalytic-domain-family-protein	unknown	unknown	gnl\|CDD\|379310
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	unknown	unknown	gnl\|CDD\|274868
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP022263.1\|WP_042675108.1\|3286728_3287043_+\|EthD-family-reductase	unknown	unknown	gnl\|CDD\|131173
NZ_CP022263.1\|WP_089112541.1\|3293194_3293446_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089112545.1\|3305479_3306391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP022263.1\|WP_089112542.1\|3293752_3294361_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_042675106.1\|3282051_3283464_-\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|223202
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP022263.1\|WP_167382306.1\|3283709_3284333_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|236494
NZ_CP022263.1\|WP_089112547.1\|3308450_3321557_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_157768141.1\|3306391_3306763_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	9.46627e-33
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	4.41203e-94
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	5.43044e-37
NZ_CP022263.1\|WP_089113555.1\|3285262_3286567_-\|threonine-synthase	gnl\|CDD\|236418	PRK09225, PRK09225, threonine synthase; Validated.	0
NZ_CP022263.1\|WP_089112539.1\|3284418_3285162_-\|murein-L,D-transpeptidase-catalytic-domain-family-protein	gnl\|CDD\|379310	pfam13645, YkuD_2, L,D-transpeptidase catalytic domain. This family is related to pfam03734.	3.79482e-96
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	2.21317e-53
NZ_CP022263.1\|WP_042675108.1\|3286728_3287043_+\|EthD-family-reductase	gnl\|CDD\|131173	TIGR02118, TIGR02118, conserved hypothetical protein. This model represents a small family of proteins of unknown function, each about 105 amino acids in length. Conserved sites in the multiple alignment include a pair of aromatic residues, a histidine, and an aspartate. [Hypothetical proteins, Conserved].	2.66662e-35
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	1.01835e-99
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	1.43976e-45
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	7.78695e-135
NZ_CP022263.1\|WP_042675106.1\|3282051_3283464_-\|histidine--tRNA-ligase	gnl\|CDD\|223202	COG0124, HisS, Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	3.07952e-148
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP022263.1\|WP_167382306.1\|3283709_3284333_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|236494	PRK09391, fixK, transcriptional regulator FixK; Provisional.	1.46458e-45
NZ_CP022263.1\|WP_089112547.1\|3308450_3321557_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	9.81689e-32

>NZ_CP022263.1|WP_089112542.1|3293752_3294361_-|hypothetical-protein
MKLNGSVFDDLYSGEKSICFFVHHGKCYWVLDHKYNFSLDAERDFKAHLDKGNISKEQYALACENFRGGVLRLNSESFLKYLELNSDVIVSRVDLEAVLNFDGIGNVLSLLNAAEKYFLSGVDLSAYDFQAAGIFSSRLPMFYVNFDREIYMHLDHGRFHEDLVYPGWVAKVFDFNFLIPEKEKYWINGGDCWKIRFIQSGF
>NZ_CP022263.1|WP_089112541.1|3293194_3293446_-|hypothetical-protein
MVGRANGGASSIQVATGTNGTAGAQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTNVQTTAAAVSSPVKQTLQK
>NZ_CP022263.1|WP_089112540.1|3291310_3291811_-|tryptophan-rich-sensory-protein
MTQHRLNTSQWFGLLGWLLLCYAVAALGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVVQLALNGLWSWLFFAWHLGAWAFADIVALWLVLAATIGAFAKKQTLAAWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP022263.1|WP_007963907.1|3288133_3290641_-|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP022263.1|WP_167382366.1|3287117_3288092_-|homoserine-kinase
MVQAQAQGSDHASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHNALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG
>NZ_CP022263.1|WP_042675108.1|3286728_3287043_+|EthD-family-reductase
MIKVSVMYPYRDGARFDHAYYRDQHMPLVSARMGAACLKYTVDKGISGGEAGSPPAFIGMCHIFCGSVETFNAGFGPHAQEILADIANYTDLTPVMQISEVVVD
>NZ_CP022263.1|WP_089113555.1|3285262_3286567_-|threonine-synthase
MFISTRGGAPAASLSQAIAAGLAPDGGLYVPQTLPPARTLVAGAGLADTATALLQPFFEGDALAAELPAICAEAFDFPAPLVALGTPGDYALELFHGPTAAFKDFGARFLAACLTRLRRAEDRPLTILVATSGDTGAAVAAAFHRQPGLRVVVLYPDGRVSPRQAHQLGCFGDNIQALRVAGSFDDCQAMVKQALNDAALQTQVPLSSANSISLGRLLPQMSYYAHAALEHHAASGSVLNLVVPTGNLGNALAAIIARALGVPLGRIALASNANHVLPDYFAGDAYVPQPSVATLANAMDVGAPSNFERLRWLYNGDDAALREEFRALSVDDAAIRHTVQQRFARYGEVHCPHTATAVHVLEQLRAEGAEGGTGDWAVAATAHPAKFEGVVEPLIGRAVEVPPALAALLQRPAQAEALAPDYAALRQRLLADAT
>NZ_CP022263.1|WP_089112539.1|3284418_3285162_-|murein-L,D-transpeptidase-catalytic-domain-family-protein
MSDRMIAVAAVLCGWAAAGAANAADALSASPVPPLGAPRVGLVEALARQAPSLDRQVLALATEALQCARQRQQVGAERVLSVIDYSRPSTERRLWVFDLDKQRLLFREWVAHGRNTGENLAAKFSNNDGSFQSSLGAFTAQESYTGHNGYSLRLKGLEPGFNDHARDRAIVIHGAPYVSEAIIRTQGRLGRSLGCPAVRPAVAKQLIDTLRDGAFVFAYYPDRAWLRQSRLLSGGCSSAAARAVAGR
>NZ_CP022263.1|WP_167382306.1|3283709_3284333_+|helix-turn-helix-domain-containing-protein
MDTLDQVTHAAAYAPGSTLVRAGETRHNVYTVTSGALRMVRTLADGRRQITGFVLPGDYVGLTETAQHRHDIEAIVDSRVCRTPMAQMRQLRERYPQLERKLLQRASMELAAAQDTGLLLARLHPSERLAHFLLRLAARSTQPGASGDTVALPMSRSDIADHLGLTVETVSRTFTKLRQQQLIALPQLHLVQILDYAALRRLAGDAV
>NZ_CP022263.1|WP_042675106.1|3282051_3283464_-|histidine--tRNA-ligase
MIKPRTPPGIMELLPREQIAFQRMLDVIRRNYERFGFLPVETPVFELSDVLLTKSGGETERQVYFVQSTGALANAAAAADEGAENGGLPELALRFDLTVPLARYVAEHEHDLSFPFRRYQMQRVYRGERAQRGRFREFYQCDIDVIGKDALSIRYDAEVLAVIHAVFAELGIGDFKVQLNNRKLLRGFFESLGVAEGELQLAVLREVDKIDKRGADYVRDTLVGEGFGIPAEQVARILAFVAVRSEGHADALAQLQALEGSVGASATLGEGIAELREVLELVKALGVPESAYCLNFSIARGLDYYTGTVYETTLTDHPQIGSICSGGRYESLASHYTKSKLPGVGISIGLTRLFWQLREAGLIQGIAESSVQAMVALMDETRLDDALDIARRLRIGGINTEVQMEPKKVGKQFQYAARAGIRFVVLAGDDELARGVVAVKDLVREQQFDVARDELASTLLVELEQAKAMP
>NZ_CP022263.1|WP_089112544.1|3300206_3305231_-|ParB-N-terminal-domain-containing-protein
MGRAATSLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQTVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALAAGNNLVSEATKAINGVGILSGITASNTLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDAVSVTTGKDLIVSAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGKVATRTNISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVDTSDTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASAATKEGGITLAAGNDVNLLADSEQHDAVQDMTKKKKGTFSSKTTTTHDEWHDNVAVTTTLSGDTVQIAAGNDLLSQGAQVASTGDLVLAAGNNLTLDTVQNTHSEEHEKTVKKSGLYGGGGFSVALGVTKKTDGLDVTEVTNTGSLVGSTDGSVTMTAGNKVSITGSDVLSATSTTIVGKEVTIAAAENTVDTVQTSKQQSAGLTLGLTGAAVEAAQAAYMATKRGSEVEDDRLKALYAAKTAYALSDAVSAYQAPPTSGGQDAVSLKIALGASSASSKTTTHDETTGGSRILSDGNVTIAATDGDLNVIGSQINGQNVTLAAANNLNLLSNKETNTSKSENKNGGGEIGVSVGTTTGFYVSAYAGKGSAKGNSELHTESVVTAKDTLTVASGNDTTIKGAQAIGDTVLAKIGGDLLIQSEQDTEDYKSKQQQAGVKLVYGVSGSSASYSQQKVNSSYTSVNEQSGIQAGNGGFDISVGGNTHLIGGAIASTADALLNHLSTGSLTVEDLQNKAEYKSGGFGVGTGDWQSVAAGAALSLARNQTGSSGSTTKSDIAAGSVEVRNGDSTALAGLDRSATELQQSGLKQVFDEKKVAEQQELAQVAGEVAFRSAKELISYKREQAAADAEQAMADLEAANGDPDATATAKARLLAANDQLAKWNDAGAAKQITQVTAGALAAAVSGGNVLSAAGGVLMNEKLLPKFADVLQKGGIQPGSGAEATLMGGLGALLGAAGGLLGGDVQAGAASGNAVQTYGYYDYREGRAQRLAMAAEALKNVGITDPNDVAGVNALLDNCVKLGCDPDKLVLLLKSPDAASTLRELAQPESVAFQRYGKGFNELDEQQRRDVINHIPTGVVSVGAVGSAHADGTAASSSEGADNSQGIAGSQQSQDENLRLKGATVVSNLAIAGGKKVEQFKNWLGEDNAETAALILMAAAGGPVKTLGSTLWAATPMAGYLQEKKEQYLVNPLTPLIGTNAFGAVTDSDQQAVQPASHATSSMLVDTLLSSLGVMGTKAGAIGIIKSSDGFSGAVKDAEKNISPPSAQELTAAITQDGSEIITRNVDPKILIGRQGRDEISGSQVKRYTKDMKANGYDVNHPIDVAKVDGKLIIIDGHHRALAAPRAGIKEVPVNVHNVTREEADQLMREAAEARGGR
>NZ_CP022263.1|WP_089112545.1|3305479_3306391_-|hypothetical-protein
MKNLSGRSDRPWELMGVFKDEFILEFNGGIYSDVDGICDKYNFLHERDGAGYRNVDYSGLLLNGKSWIIEPLRLLQPNSYQAFQEAAEPLLLGVMLIEDLRNPGGPPMVRPILFLEVHGRMVEVFATFPSSTYEDGNDCFGSLLSLPDGLAKSWLWRTDGWRIPGSVGEGPMTNRQLIGHPSSRWRDADTYLDSLGKGWKKKYLPKIKELFPDAVTNINGVKRIKFRCFLDTRPVGVGGPEGDQFFVCSTRQDQVVYHVHEGNVENLRVLRNPEDAIDRYCAHVLRRKPGQFDFSDWSEPFRP
>NZ_CP022263.1|WP_157768141.1|3306391_3306763_-|hypothetical-protein
MNAKNELTWINPLTGVKEAVPATAKIHVDHVLPQNAIRQIDGFDSLPKSVQNEIMKDPANLQPMIKSANCSKGCKVEAEGAGWMTWNGKPVSEKYKMYLEEAQQDFRTKVSKIIDDNNALKGK
>NZ_CP022263.1|WP_089111250.1|3307379_3308360_+|IS5-family-transposase
MQLTFGDAEGLGKRKQTRREIFLAEMEQVVPWQQLLWLIAPHYPVSGRPGRQPYALATMLRIHLLQQWYALSDPAMEEALHEIPTLRRFAQLGGLDDIPDETTILNFRRLLETHGLAARMLEAVNAHLARKGQSLRSGTIVDATLIAAPSSTKNADHARDPEMHQTRKGNQWYFGMKAHIGVDEFSGLVHHVHCTAANVADVTVMHTLLHGKEDSVFGDSGYTGADKREELQDCEAAFFIAARPSTIQAIANKCERAQEQRWERFKASVRAKVEHPFRVIKRQFGYTKVRYRGLAKNTAQVLTLFALSNLWMKRKQLLPAMGSVRL
>NZ_CP022263.1|WP_089112547.1|3308450_3321557_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MDNEAMRVRGYLAEQGKRALALLLCCTTTWTSFPAWAQVAPTANPAGQTPGQQVAANGVPVVEIVAPNARGISHNRYSNFNVGPNGLILNNSAQISKTELGGYVAGNNNLQRSGAASLILNEVTSASSRLQGYTEIAGAKAQLVIANPNGISCDGCGFLNTSRVTLTTGTPNLGSDGALNGFSITGGALSIGRNGLDAFNVDRLDLLSRQLSVDGSVWTRELVAAAGAGRVNYDGMLLDVLPGADGAAPAIGIDVAQLGGMYAERIRLIATEAGVGVVSRGTLAAQSGDLQIDSAGQLSLSGTTVARDAVNVRATGALDQRGVLGSQQGDVYLRAANMTLAGDLVAAGALDAQAGGVVNHGGRSSAGSIRLFGPQLNADGSLHTNGALDLGADGLLSSSGVAYGGAGANLRAAQIALSGTLQSGAAIALNATTIDALGTLDAATALQFKGNGDVRLAGLAQAGQGADVQAGGRLELQGQLIAADALALNAASTDIAQRAAVSAGNDLDLRSAGAVNNAGSAYAGRDLRLQAASVTTAGSLSAARDAQLSVEGQLLNSGTIVAGDALAVNAAQLASSGDIGSQRGDATLRSRGNLRLSGNTVAGGALALDAASSAQVSGTVNAASVNLRSGGDAILSGTLQSTRGALTVAAASELANDAVLRSASALDLQADGALRQRGQLHSNGGVQLRGGSVAHNGLIDAGGDLRIASAGALALDGTVQSAGSTTLQAAGALDNSAKVVTAGPLQMDASSLHNAQGAAFSSGADAQLRIGGTLENAGSVYAANALQISADSLTQNGSVGSGNTLSATVAGTFDNAGNVVARDGLQIDAGDLRSSGQLGSEAAGVVLGSQSDIALQGVVAATTTLQANAAGDLQQSGSLKAQSVALRAGRDLAASGTLQSASTLDLQAQRDLTFTAQGQAGGDIGMRAATLTTSQDAVLQGAAAIALDSGTIHSRGKLDAGSDLRVHSLGDLTLAGIAQGSGDVELTATGALTNAAQVFAGRTLTAQAQSLENTAAGVLAGDGNVALTAAAQLRNAGRVQAAGDLQMTAASLDQSGSASAGKTLRGTVAGTLDNRGNLIARDALQIDAGTLRSSGQLGSELASVALSSQGAMQLDGVVAAATALQASAGGDLQQAGSLKAQSIALQARQDLTANGSLQSASTLDLQSQCTLALNGQASSAADATLDGATITTSAVAVLQSGASITLAGDSIDSRGALDAANDLTLRSAGDLTLGGVAQAGRDIALTATGNLNNGAQVIAARDLSVQAASAANASDATLGAKRDLRVDVAGVLDNRGSLHGERGLSLTSGSLLQRGRVYSGDALSIASNGAFENAGQLVSGKELSITAGSIVSNGQLGSVTGALALTSQNAIALQGVVSAATTLQATAGGDLSQAGTLSAQTVALQAGRDLVAGGTLQSASTLDVQAQRTLSLNGQAQAGTDASLHSNSIVTGRDAVLKSGGAITLDGAAIDSRGTLDAGTDLVVRSTGDLALAGVAQANRDVVLSASGALGSASQVFAGRNLSLQAGSINNAAAGALAAAGGVTLATGALQNAGSLQSGGDLRITAASMDQSGTAVAGKALTATVTGTLDNRGSLIAKDAVLVEAGTLRSSGQLGSEASTVTLTSRGDMTLQGVVAAASTLHAAAGGDLHQAGSLKAQSIALQAGRDLTAAGTLQSASQLDLQAQRALNFNGQAVSAANANLRGAQIATGQAAVLQSGVAISLDGAAIDSRGALDAASDVNLRSTGDLAVAGVVQAERNVVLSAAGALTNAAQVVAGDGLTVTAASASNTATGVLLAQGDTTLSIAGLLDNAGVVRAGNQLSLNVGSLRQTGQAYGLQRLGVSASGAVDNRGDLIGGNALRVEAGQLSNSGQLGSERGDVALISRGDLQLNGRLASAGAFTAQADGALTQSGNLSAASTLDLRSKGDLTIAGQVAGQQLALVSDAVVRQQGTVSGTTVDVQGARIENAGQTTAAGNLSLRAGEIGITGTVGAGINADGSLGSGSTLSLVADGQFAASGTLLAGGNLTAQGSQLQLAGSTTRATGNVALATGGSLDHRGGNLLAGGTLTAQAGGNIDNGRLNNMGGQLQANQLSIDGGSLSNVGGALVQSGAGLTRVAIGGAIDNTAGTLASNGQDLTVTAASIENAQGRIEHAGAGTLSVTSRAAFGNSSGRILTQGQLTLGASGALNNQSGAIAAAGDAGVTAASLNNLAGSVSARTLNVQTSGAVDNRNGLLQASGGALTLRADSLSNAGGTVQAVANAGAGGGLRVELNRGLDNGNGTIGASTDAVITAENISSAGGNLQAGRDLSITARGQLDNHQGGKLSAGRDLSVAVAGALLNSGDQLDAGNTLTASGGLIDNTQGSIVSNGSGLTRLTTGGALTNTSGNLGGRGSVVIDAASIANTSGQLVAGGDLIANTNVLDNQGGSVYAGANFLLQRAGATLDNQSGRIKAEQSVRLNLQNLSNAGGQIGAGSVTGGVGDVLIDTVGFDGGGSILAQNLLDLTLRSDYTHRAGADLVSNGNFNLRVGGNLVNESTLKAARTLDITASSITNRAGANILSNDTRLNGGNVIDNAGSVSGNGALLLVANSVYNTGSIVGGNVSVNTGTLVNGADLGGATDNAAYGSALLGSTGNMNLIVRDQLLNRDARIFSLGNIAIGGAQDGGGTLVSRTGVVNNLSGSIEADGSILIAANQLNNRRRVVNTTSVSTDPGNDDVYSGGELIEGKAIRNIQGARAPYPYKGLAPGIYRNYQVIQQEQLSSASAEGRIAAGGNILLSGSVTNNASTIAAAGVFAANQRGLGGLSDGMIVGGEQLLNQALALNQTVRQSDVEHIVTAITNDCMQPVGQKVVCYYEEEDQRLSSSTVSSSYIALGASMTGNQGVSINGANISNGAVGSDGRSISGASLNGVGAQGGLNGRTTQSAVGVGGQAVVGRASGGAGSIRVATGTSGSAGTQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTHVQTTAASTGVTAGANETRTRVDPATIPVANIVGGGQTSLTQIDLPIGGLYRLSSGTGTDLNAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQKVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGNNLVSEAAKAINGIGILSGITASNSLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDVVSVSTGKDLIVAAGNDLQLHGVSINAGGSAALQAGNNLSLTPTTGLDGKVASRTSISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVETSNTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAATAATKDGGITLAAGNDVNLLAASEQHDAVQDMTKKKKGTFSSKTTTTHDEWHDNVAVTTTLSGDTVQIAAGNDLLSQGAQVASTGDVVLAAGNNLTLDTVQNTHSEEHEKTVKKSGLYGGGGFSVALGVTKKTDGLDVTEVTNTGSLVGSTDGAVTMTAGNKVAITGSDVLSTTSTTIVGKNVTIAAAENTVDTVQTSKQQSAGITLGLTGGAVDAAQAIYGAAKRGSEVEDDRLKALYAAKAGYAVSDTAGLVSNGLKGYDGQAVAGNMTKTGAAAADGAQGAANAAGVSLRLGIGASSSSSKTTTHEETTGGSRILSNGDITIAATGGDLNVIGSKIAGENVALAAANNLNLLSNKETNTTKSENKNAGGEIGISVGAVTGYYLSVSAGKGSAKGNSDLRTESVITANNTLTLVSGNDTTIQGAQAVGNKVLANVGGNLLIKSEQDTNEYKSKQQQASLTLATGSGSGGSYSQQKVNSSYTSVTEQSGIQAGNGGFDITVGGATKLVGGAIASAADASLNRLSTGSLTVEDLQNKAEYKTSGVSVAGGTGSSMASMAIGTGLSMLGNSSDSSSSTTKSDIAAGSIQIRNGDQSALAGLDRSATELQQSGLKEIFDQKKIEDQKELMGLAGEIGFRVAGDVASAMYQKAQLDLASAPDEASKAQALARLDAWSDGGTNKILLHGLTGAAIAALGGENVLQTAAGAAGAEAAKVAMSDYLVKNGVTDAATYNALMELGSAALGGIAGGQVGATTALAGDQFNRQLHPDEVTWIRQNAEAFALQEGIREGLNNDA
>NZ_CP022263.1|WP_089112548.1|3321627_3323328_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREDADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGDSHDLATRNEERGTRGNSLSYSLPWGWWTFALAASSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPVYGARVIYQF
>NZ_CP022263.1|WP_089112549.1|3324059_3326018_+|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPEYPDDAGLQRLGASLERQRGWQVHLSHAWGHSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDEWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGPAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDETRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQREQQLGLDLDFRWGGTP
>NZ_CP022263.1|WP_089112550.1|3325999_3327898_+|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRWRIETDLRHSRDAVVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQIDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQLPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP022263.1|WP_046832236.1|3327901_3329155_+|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP022263.1|WP_022559030.1|3329151_3329598_+|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVNADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR

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Crispr_ID: NZ_CP022263_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022263_6

3310998-3311083

Orphan

Consensus_repeat	Method
GTTGATGTCGTTGCCGGCGCTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022263_6

>merge|NZ_CP022263|6|3310998-3311083|CRISPRCasFinder
GTTGATGTCGTTGCCGGCGCTGATCCCCAAGCCTTTGCCTGCATCGAGCTTTGCGGCGACCAGGTTGACGTCGTTGCCGGCGCTGA

>NZ_CP022263|6|6|3310998-3311083|CRISPRCasFinder
GTTGATGTCGTTGCCGGCGCTGA	TCCCCAAGCCTTTGCCTGCATCGAGCTTTGCGGCGACCAG
GTTGACGTCGTTGCCGGCGCTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022263.1\|WP_026007260.1\|3332284_3332569_+\|DUF4190-domain-containing-protein	unknown	unknown	gnl\|CDD\|379388
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	unknown	unknown	gnl\|CDD\|274868
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP022263.1\|WP_089112542.1\|3293752_3294361_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089112541.1\|3293194_3293446_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089112545.1\|3305479_3306391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP022263.1\|WP_089112543.1\|3294357_3299679_-\|hemagglutinin	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_167382307.1\|3332571_3333339_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP022263.1\|WP_022559029.1\|3330170_3331703_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448
NZ_CP022263.1\|WP_157768143.1\|3331870_3332080_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_007965740.1\|3333344_3334400_+\|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235388
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP022263.1\|WP_157768141.1\|3306391_3306763_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022263.1\|WP_026007260.1\|3332284_3332569_+\|DUF4190-domain-containing-protein	gnl\|CDD\|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	4.67005e-11
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	9.46627e-33
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	4.41203e-94
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	5.43044e-37
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	1.43976e-45
NZ_CP022263.1\|WP_007965740.1\|3333344_3334400_+\|quinone-dependent-dihydroorotate-dehydrogenase	gnl\|CDD\|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	0
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	2.21317e-53
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	1.01835e-99
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP022263.1\|WP_089112543.1\|3294357_3299679_-\|hemagglutinin	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	3.65769e-46
NZ_CP022263.1\|WP_167382307.1\|3332571_3333339_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.18165e-17
NZ_CP022263.1\|WP_022559029.1\|3330170_3331703_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	7.78695e-135

>NZ_CP022263.1|WP_089111250.1|3307379_3308360_+|IS5-family-transposase
MQLTFGDAEGLGKRKQTRREIFLAEMEQVVPWQQLLWLIAPHYPVSGRPGRQPYALATMLRIHLLQQWYALSDPAMEEALHEIPTLRRFAQLGGLDDIPDETTILNFRRLLETHGLAARMLEAVNAHLARKGQSLRSGTIVDATLIAAPSSTKNADHARDPEMHQTRKGNQWYFGMKAHIGVDEFSGLVHHVHCTAANVADVTVMHTLLHGKEDSVFGDSGYTGADKREELQDCEAAFFIAARPSTIQAIANKCERAQEQRWERFKASVRAKVEHPFRVIKRQFGYTKVRYRGLAKNTAQVLTLFALSNLWMKRKQLLPAMGSVRL
>NZ_CP022263.1|WP_157768141.1|3306391_3306763_-|hypothetical-protein
MNAKNELTWINPLTGVKEAVPATAKIHVDHVLPQNAIRQIDGFDSLPKSVQNEIMKDPANLQPMIKSANCSKGCKVEAEGAGWMTWNGKPVSEKYKMYLEEAQQDFRTKVSKIIDDNNALKGK
>NZ_CP022263.1|WP_089112545.1|3305479_3306391_-|hypothetical-protein
MKNLSGRSDRPWELMGVFKDEFILEFNGGIYSDVDGICDKYNFLHERDGAGYRNVDYSGLLLNGKSWIIEPLRLLQPNSYQAFQEAAEPLLLGVMLIEDLRNPGGPPMVRPILFLEVHGRMVEVFATFPSSTYEDGNDCFGSLLSLPDGLAKSWLWRTDGWRIPGSVGEGPMTNRQLIGHPSSRWRDADTYLDSLGKGWKKKYLPKIKELFPDAVTNINGVKRIKFRCFLDTRPVGVGGPEGDQFFVCSTRQDQVVYHVHEGNVENLRVLRNPEDAIDRYCAHVLRRKPGQFDFSDWSEPFRP
>NZ_CP022263.1|WP_089112544.1|3300206_3305231_-|ParB-N-terminal-domain-containing-protein
MGRAATSLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQTVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALAAGNNLVSEATKAINGVGILSGITASNTLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDAVSVTTGKDLIVSAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGKVATRTNISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVDTSDTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASAATKEGGITLAAGNDVNLLADSEQHDAVQDMTKKKKGTFSSKTTTTHDEWHDNVAVTTTLSGDTVQIAAGNDLLSQGAQVASTGDLVLAAGNNLTLDTVQNTHSEEHEKTVKKSGLYGGGGFSVALGVTKKTDGLDVTEVTNTGSLVGSTDGSVTMTAGNKVSITGSDVLSATSTTIVGKEVTIAAAENTVDTVQTSKQQSAGLTLGLTGAAVEAAQAAYMATKRGSEVEDDRLKALYAAKTAYALSDAVSAYQAPPTSGGQDAVSLKIALGASSASSKTTTHDETTGGSRILSDGNVTIAATDGDLNVIGSQINGQNVTLAAANNLNLLSNKETNTSKSENKNGGGEIGVSVGTTTGFYVSAYAGKGSAKGNSELHTESVVTAKDTLTVASGNDTTIKGAQAIGDTVLAKIGGDLLIQSEQDTEDYKSKQQQAGVKLVYGVSGSSASYSQQKVNSSYTSVNEQSGIQAGNGGFDISVGGNTHLIGGAIASTADALLNHLSTGSLTVEDLQNKAEYKSGGFGVGTGDWQSVAAGAALSLARNQTGSSGSTTKSDIAAGSVEVRNGDSTALAGLDRSATELQQSGLKQVFDEKKVAEQQELAQVAGEVAFRSAKELISYKREQAAADAEQAMADLEAANGDPDATATAKARLLAANDQLAKWNDAGAAKQITQVTAGALAAAVSGGNVLSAAGGVLMNEKLLPKFADVLQKGGIQPGSGAEATLMGGLGALLGAAGGLLGGDVQAGAASGNAVQTYGYYDYREGRAQRLAMAAEALKNVGITDPNDVAGVNALLDNCVKLGCDPDKLVLLLKSPDAASTLRELAQPESVAFQRYGKGFNELDEQQRRDVINHIPTGVVSVGAVGSAHADGTAASSSEGADNSQGIAGSQQSQDENLRLKGATVVSNLAIAGGKKVEQFKNWLGEDNAETAALILMAAAGGPVKTLGSTLWAATPMAGYLQEKKEQYLVNPLTPLIGTNAFGAVTDSDQQAVQPASHATSSMLVDTLLSSLGVMGTKAGAIGIIKSSDGFSGAVKDAEKNISPPSAQELTAAITQDGSEIITRNVDPKILIGRQGRDEISGSQVKRYTKDMKANGYDVNHPIDVAKVDGKLIIIDGHHRALAAPRAGIKEVPVNVHNVTREEADQLMREAAEARGGR
>NZ_CP022263.1|WP_089112543.1|3294357_3299679_-|hemagglutinin
MGRAANGLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQKVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRINGTGSVALEARNDLLNQGQIQGRDVALVAGNNLVSEAAKAINGIGILSGITASNSLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLLRGGDAVSVSTGKDLIVAAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGQVATRTNISTGDSLQLTAGNDLTIRQAEVKAGGDLIAAAGNNLNVESVLNDSETNSYNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVETSNTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASVATKEGGITLAAGNDVNLLAASEQHDAVQDMTKKKKGTFSSKTTTTHDAWQDNVAVTTTLSGDTVQIAAGNDLLSQGAQVVGTGDVTLAAGNNLTLETAQNTHSEEHDKVTTKSGLFGSGGIGVTLGKQKVTTGADIDQITHSGTTIGSLEGDVTLGAGNKLAITGSDVMALQGDLTATGKDIAITEVYNDNDAEQRSKFSQGGLSLTLSSAAISLAQAANDSYKASKEVKGDSRMEALALGSAAYSAYGAGQALGQAGSALSSGSAAGAAQGANLSIAISIGGSKSESKSTQTASLAQGSKLQAGGDVNLIATGGGDQSNLLIRGSDIKAGNDLLLAADHDVLIEAAKNTAEQKSTSKSSSASLGVGITYGPDGAAFGVMISAAGSRGKANGEDVTYTNSHLAAGNTATVISGNDTTLKGAQLSADKVIADVGGNLSIESLQDTSTYDSKDKSVGASVTFGAGFSASASYSSNKVNGDFASVTEQSGIQAGDGGFNIRVGGNTDLKGAVIASTQVAVDAGVNRLQTGTLTYSDIENTSTYDAKGFSLSGGYSKGTGDKKQGETGQVQPTVNNGANWSWQNFQTGSTGTAAGIGSKSGDATSTTTSGISGGSLLITDEAGQLAKSGKTAADALAGLKRDVISGDDAGGLTKQWDGQALRDQVAAQAQITATAGQQATKFVGDYAQGRVDKAAELYAEADASGDDSKRAEADQLMRDWGDGGTLRVLSHAVVGGLTGGTDGALGAAAGTVAAPYLAEALEKAGINKAVAATLTGLSASALGAAAGGAAGGAAALNEVSNNYLGHQERMEYATALIACSKSGTLCERAEQLKALSEERNLQLRGACSDPASGACAEQKQLAAVAMQDQLDHAGEYTTWLAGHVPELASLFNSDKDGTLTKDFVTHVTTADLGHKLACAMAGGCSNQALASAAWNGSIPLSVATADSALRAALGMGAGAVGATGRVWEMVSGVAQLAKDTSPAGQIGKTIDQLAYLWGNGYAATADKNFNDAKGALNAIKTGISGYAEDLAFAAYTNTHGSWDIYDIAKAGAIGGKVSVDVLSLVVPELYVGKGGVAAKAAIDVGDAFKADDVIDYINSKRPSPSGSNKGEAGSAATPELVNYFRVEGGGAGAATSKNRITANSDGSISINPGCSGQLCVSVGTADHAVYYLSNKRPDGSVVVFEVDASLHSEIMNSAIPQRPIPGVPRDPTAPKIVDPNKPGTALELPKVWESLLESGSRNARVYSHDEFLKEFGE
>NZ_CP022263.1|WP_089112542.1|3293752_3294361_-|hypothetical-protein
MKLNGSVFDDLYSGEKSICFFVHHGKCYWVLDHKYNFSLDAERDFKAHLDKGNISKEQYALACENFRGGVLRLNSESFLKYLELNSDVIVSRVDLEAVLNFDGIGNVLSLLNAAEKYFLSGVDLSAYDFQAAGIFSSRLPMFYVNFDREIYMHLDHGRFHEDLVYPGWVAKVFDFNFLIPEKEKYWINGGDCWKIRFIQSGF
>NZ_CP022263.1|WP_089112541.1|3293194_3293446_-|hypothetical-protein
MVGRANGGASSIQVATGTNGTAGAQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTNVQTTAAAVSSPVKQTLQK
>NZ_CP022263.1|WP_089112540.1|3291310_3291811_-|tryptophan-rich-sensory-protein
MTQHRLNTSQWFGLLGWLLLCYAVAALGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVVQLALNGLWSWLFFAWHLGAWAFADIVALWLVLAATIGAFAKKQTLAAWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP022263.1|WP_007963907.1|3288133_3290641_-|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP022263.1|WP_167382366.1|3287117_3288092_-|homoserine-kinase
MVQAQAQGSDHASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHNALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG
>NZ_CP022263.1|WP_089112548.1|3321627_3323328_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREDADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGDSHDLATRNEERGTRGNSLSYSLPWGWWTFALAASSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPVYGARVIYQF
>NZ_CP022263.1|WP_089112549.1|3324059_3326018_+|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPEYPDDAGLQRLGASLERQRGWQVHLSHAWGHSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDEWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGPAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDETRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQREQQLGLDLDFRWGGTP
>NZ_CP022263.1|WP_089112550.1|3325999_3327898_+|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRWRIETDLRHSRDAVVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQIDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQLPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP022263.1|WP_046832236.1|3327901_3329155_+|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP022263.1|WP_022559030.1|3329151_3329598_+|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVNADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR
>NZ_CP022263.1|WP_022559029.1|3330170_3331703_+|aldehyde-dehydrogenase-family-protein
MSADLLKALDLAASNSGTYLGEATWSQATGAGVLQPLNPATNAVIAEVQATTPEDYELIVQRAQAAFKVWRTTPAPRRGEAVRLCGEALRAHKDALGSLVALEMGKSKPEGDGEVQEMIDIADFAVGQSRMLYGYTMHSERPGHRMYEQYQPLGLVGIISAFNFPVAVWAWNAFLAAICGDICIWKPSNKTPLTAIATMKICNAALKDAGFPDIFFLINDAGTALSEKLVEDTRVPLISFTGSTQIGRVVAEKVARRLGRCLLELGGNNAIILDETADLKLAIPGIVFGAVGTAGQRCTTTRRLIVHASIYDTVLATLVKAYKQLDSKIGDPTDPANLMGPLNSQGAVAQFLDSIAKAKAAGGTVEVGGTAIDRPGNFVLPAIVTGLQNSDAVVQHETFAPILYVMKYSTLDEAIELQNGVPQGLSSSIFTQNLKAAEKFLSAAGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKVYMRRQTNTINYSDSLPLAQGIRFDL
>NZ_CP022263.1|WP_157768143.1|3331870_3332080_-|hypothetical-protein
MRFALATLSFAGRQLLLQSKLRVVAGRGFVQQRQAFGFTSTRIRSRSQSLSACIRMSSQHGCIAKGRAG
>NZ_CP022263.1|WP_026007260.1|3332284_3332569_+|DUF4190-domain-containing-protein
MNVVVRQTSAMAIVSLVAGILGWTLIPFLGSICAIITGHLARAEIRRNPQALDGDGLAIGGLIMGWLAVALWIVGIAFFLLFFGGMAWLAAANS
>NZ_CP022263.1|WP_167382307.1|3332571_3333339_+|class-I-SAM-dependent-methyltransferase
MATPSSAQRFNDRVAAYVRYRPSYPPQLLRWLHGELGVTPATAVTDIGAGTGISSRLFLEAGYAVTAVEPNQAMREAALQWLAEYPKFQAIAGTAEATGLGDASVGLVSAAQAFHWFDMQAVRDEWARILQPGGLAVVYWNSRELDSTAFLRGYEQLLLDFGTDYSAVAERYQDDATMQAWFGEGFRAMARFPNVQRLDFESLRGRLLSSSYAPLAHDPRHAPMLAALRTLFDAYAYDGLIDFQYQTRVFAGRLN
>NZ_CP022263.1|WP_007965740.1|3333344_3334400_+|quinone-dependent-dihydroorotate-dehydrogenase
MYSLARPFLFSLDAERAHALALRSIDTAYRTGTTALLARRPVPLPTPAFGLMFPNPVGLGAGLDKNGEHIDALFALGFGFVEIGTVTPRAQEGNPKPRMFRLPEYQAVINRMGFNNLGVDALVANVQRARRTAGLLGINIGKNKDTPNEEATSDYRYCMERVYPLADYITVNISSPNTAGLRELQEEQSLRRLISDLRETQEALSAQHGKRVPMLVKVAPDLNDRDIDAAARVLADLAVDGVIATNTTVTRTLVANHPLAAEAGGLSGAPLLGQSTLVLRRLRARLPESIPLIGVGGINSGADAVAKMAAGASLVQCYSGLVYRGPQLIGECVNAIRRRREAPSGGAVSPL

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Crispr_ID: NZ_CP022263_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022263_5

3310782-3310871

Orphan

Consensus_repeat	Method
GTTGATGTCGTTGCCGGCGCTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022263_5

>merge|NZ_CP022263|5|3310782-3310871|CRISPRCasFinder
GTTGACGTCGTTGCCGGCGGCCAGGGTGATGCCGCCGTCCTTGGTGGCGGCCGTGGCAGCGGTAAGGGTGATGTCGTTGCCCGCCTGCAT

>NZ_CP022263|5|5|3310782-3310871|CRISPRCasFinder
GTTGACGTCGTTGCCGGCGGCCA	GGGTGATGCCGCCGTCCTTGGTGGCGGCCGTGGCAGCGGTAAG
GGTGATGTCGTTGCCCGCCTGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022263.1\|WP_026007260.1\|3332284_3332569_+\|DUF4190-domain-containing-protein	unknown	unknown	gnl\|CDD\|379388
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	unknown	unknown	gnl\|CDD\|274868
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP022263.1\|WP_089112542.1\|3293752_3294361_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089112541.1\|3293194_3293446_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_089112545.1\|3305479_3306391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP022263.1\|WP_089112543.1\|3294357_3299679_-\|hemagglutinin	unknown	unknown	gnl\|CDD\|379124
NZ_CP022263.1\|WP_167382307.1\|3332571_3333339_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP022263.1\|WP_022559029.1\|3330170_3331703_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448
NZ_CP022263.1\|WP_157768143.1\|3331870_3332080_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_007965740.1\|3333344_3334400_+\|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235388
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP022263.1\|WP_157768141.1\|3306391_3306763_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022263.1\|WP_026007260.1\|3332284_3332569_+\|DUF4190-domain-containing-protein	gnl\|CDD\|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	4.67005e-11
NZ_CP022263.1\|WP_089111250.1\|3307379_3308360_+\|IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	9.46627e-33
NZ_CP022263.1\|WP_167382366.1\|3287117_3288092_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	4.41203e-94
NZ_CP022263.1\|WP_007963907.1\|3288133_3290641_-\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP022263.1\|WP_089112544.1\|3300206_3305231_-\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	5.43044e-37
NZ_CP022263.1\|WP_089112540.1\|3291310_3291811_-\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	1.43976e-45
NZ_CP022263.1\|WP_007965740.1\|3333344_3334400_+\|quinone-dependent-dihydroorotate-dehydrogenase	gnl\|CDD\|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	0
NZ_CP022263.1\|WP_022559030.1\|3329151_3329598_+\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	2.21317e-53
NZ_CP022263.1\|WP_089112549.1\|3324059_3326018_+\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	1.01835e-99
NZ_CP022263.1\|WP_046832236.1\|3327901_3329155_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP022263.1\|WP_089112550.1\|3325999_3327898_+\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP022263.1\|WP_089112543.1\|3294357_3299679_-\|hemagglutinin	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	3.65769e-46
NZ_CP022263.1\|WP_167382307.1\|3332571_3333339_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.18165e-17
NZ_CP022263.1\|WP_022559029.1\|3330170_3331703_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0
NZ_CP022263.1\|WP_089112548.1\|3321627_3323328_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	7.78695e-135

>NZ_CP022263.1|WP_089111250.1|3307379_3308360_+|IS5-family-transposase
MQLTFGDAEGLGKRKQTRREIFLAEMEQVVPWQQLLWLIAPHYPVSGRPGRQPYALATMLRIHLLQQWYALSDPAMEEALHEIPTLRRFAQLGGLDDIPDETTILNFRRLLETHGLAARMLEAVNAHLARKGQSLRSGTIVDATLIAAPSSTKNADHARDPEMHQTRKGNQWYFGMKAHIGVDEFSGLVHHVHCTAANVADVTVMHTLLHGKEDSVFGDSGYTGADKREELQDCEAAFFIAARPSTIQAIANKCERAQEQRWERFKASVRAKVEHPFRVIKRQFGYTKVRYRGLAKNTAQVLTLFALSNLWMKRKQLLPAMGSVRL
>NZ_CP022263.1|WP_157768141.1|3306391_3306763_-|hypothetical-protein
MNAKNELTWINPLTGVKEAVPATAKIHVDHVLPQNAIRQIDGFDSLPKSVQNEIMKDPANLQPMIKSANCSKGCKVEAEGAGWMTWNGKPVSEKYKMYLEEAQQDFRTKVSKIIDDNNALKGK
>NZ_CP022263.1|WP_089112545.1|3305479_3306391_-|hypothetical-protein
MKNLSGRSDRPWELMGVFKDEFILEFNGGIYSDVDGICDKYNFLHERDGAGYRNVDYSGLLLNGKSWIIEPLRLLQPNSYQAFQEAAEPLLLGVMLIEDLRNPGGPPMVRPILFLEVHGRMVEVFATFPSSTYEDGNDCFGSLLSLPDGLAKSWLWRTDGWRIPGSVGEGPMTNRQLIGHPSSRWRDADTYLDSLGKGWKKKYLPKIKELFPDAVTNINGVKRIKFRCFLDTRPVGVGGPEGDQFFVCSTRQDQVVYHVHEGNVENLRVLRNPEDAIDRYCAHVLRRKPGQFDFSDWSEPFRP
>NZ_CP022263.1|WP_089112544.1|3300206_3305231_-|ParB-N-terminal-domain-containing-protein
MGRAATSLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQTVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALAAGNNLVSEATKAINGVGILSGITASNTLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDAVSVTTGKDLIVSAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGKVATRTNISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVDTSDTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASAATKEGGITLAAGNDVNLLADSEQHDAVQDMTKKKKGTFSSKTTTTHDEWHDNVAVTTTLSGDTVQIAAGNDLLSQGAQVASTGDLVLAAGNNLTLDTVQNTHSEEHEKTVKKSGLYGGGGFSVALGVTKKTDGLDVTEVTNTGSLVGSTDGSVTMTAGNKVSITGSDVLSATSTTIVGKEVTIAAAENTVDTVQTSKQQSAGLTLGLTGAAVEAAQAAYMATKRGSEVEDDRLKALYAAKTAYALSDAVSAYQAPPTSGGQDAVSLKIALGASSASSKTTTHDETTGGSRILSDGNVTIAATDGDLNVIGSQINGQNVTLAAANNLNLLSNKETNTSKSENKNGGGEIGVSVGTTTGFYVSAYAGKGSAKGNSELHTESVVTAKDTLTVASGNDTTIKGAQAIGDTVLAKIGGDLLIQSEQDTEDYKSKQQQAGVKLVYGVSGSSASYSQQKVNSSYTSVNEQSGIQAGNGGFDISVGGNTHLIGGAIASTADALLNHLSTGSLTVEDLQNKAEYKSGGFGVGTGDWQSVAAGAALSLARNQTGSSGSTTKSDIAAGSVEVRNGDSTALAGLDRSATELQQSGLKQVFDEKKVAEQQELAQVAGEVAFRSAKELISYKREQAAADAEQAMADLEAANGDPDATATAKARLLAANDQLAKWNDAGAAKQITQVTAGALAAAVSGGNVLSAAGGVLMNEKLLPKFADVLQKGGIQPGSGAEATLMGGLGALLGAAGGLLGGDVQAGAASGNAVQTYGYYDYREGRAQRLAMAAEALKNVGITDPNDVAGVNALLDNCVKLGCDPDKLVLLLKSPDAASTLRELAQPESVAFQRYGKGFNELDEQQRRDVINHIPTGVVSVGAVGSAHADGTAASSSEGADNSQGIAGSQQSQDENLRLKGATVVSNLAIAGGKKVEQFKNWLGEDNAETAALILMAAAGGPVKTLGSTLWAATPMAGYLQEKKEQYLVNPLTPLIGTNAFGAVTDSDQQAVQPASHATSSMLVDTLLSSLGVMGTKAGAIGIIKSSDGFSGAVKDAEKNISPPSAQELTAAITQDGSEIITRNVDPKILIGRQGRDEISGSQVKRYTKDMKANGYDVNHPIDVAKVDGKLIIIDGHHRALAAPRAGIKEVPVNVHNVTREEADQLMREAAEARGGR
>NZ_CP022263.1|WP_089112543.1|3294357_3299679_-|hemagglutinin
MGRAANGLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQKVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRINGTGSVALEARNDLLNQGQIQGRDVALVAGNNLVSEAAKAINGIGILSGITASNSLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLLRGGDAVSVSTGKDLIVAAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGQVATRTNISTGDSLQLTAGNDLTIRQAEVKAGGDLIAAAGNNLNVESVLNDSETNSYNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVETSNTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASVATKEGGITLAAGNDVNLLAASEQHDAVQDMTKKKKGTFSSKTTTTHDAWQDNVAVTTTLSGDTVQIAAGNDLLSQGAQVVGTGDVTLAAGNNLTLETAQNTHSEEHDKVTTKSGLFGSGGIGVTLGKQKVTTGADIDQITHSGTTIGSLEGDVTLGAGNKLAITGSDVMALQGDLTATGKDIAITEVYNDNDAEQRSKFSQGGLSLTLSSAAISLAQAANDSYKASKEVKGDSRMEALALGSAAYSAYGAGQALGQAGSALSSGSAAGAAQGANLSIAISIGGSKSESKSTQTASLAQGSKLQAGGDVNLIATGGGDQSNLLIRGSDIKAGNDLLLAADHDVLIEAAKNTAEQKSTSKSSSASLGVGITYGPDGAAFGVMISAAGSRGKANGEDVTYTNSHLAAGNTATVISGNDTTLKGAQLSADKVIADVGGNLSIESLQDTSTYDSKDKSVGASVTFGAGFSASASYSSNKVNGDFASVTEQSGIQAGDGGFNIRVGGNTDLKGAVIASTQVAVDAGVNRLQTGTLTYSDIENTSTYDAKGFSLSGGYSKGTGDKKQGETGQVQPTVNNGANWSWQNFQTGSTGTAAGIGSKSGDATSTTTSGISGGSLLITDEAGQLAKSGKTAADALAGLKRDVISGDDAGGLTKQWDGQALRDQVAAQAQITATAGQQATKFVGDYAQGRVDKAAELYAEADASGDDSKRAEADQLMRDWGDGGTLRVLSHAVVGGLTGGTDGALGAAAGTVAAPYLAEALEKAGINKAVAATLTGLSASALGAAAGGAAGGAAALNEVSNNYLGHQERMEYATALIACSKSGTLCERAEQLKALSEERNLQLRGACSDPASGACAEQKQLAAVAMQDQLDHAGEYTTWLAGHVPELASLFNSDKDGTLTKDFVTHVTTADLGHKLACAMAGGCSNQALASAAWNGSIPLSVATADSALRAALGMGAGAVGATGRVWEMVSGVAQLAKDTSPAGQIGKTIDQLAYLWGNGYAATADKNFNDAKGALNAIKTGISGYAEDLAFAAYTNTHGSWDIYDIAKAGAIGGKVSVDVLSLVVPELYVGKGGVAAKAAIDVGDAFKADDVIDYINSKRPSPSGSNKGEAGSAATPELVNYFRVEGGGAGAATSKNRITANSDGSISINPGCSGQLCVSVGTADHAVYYLSNKRPDGSVVVFEVDASLHSEIMNSAIPQRPIPGVPRDPTAPKIVDPNKPGTALELPKVWESLLESGSRNARVYSHDEFLKEFGE
>NZ_CP022263.1|WP_089112542.1|3293752_3294361_-|hypothetical-protein
MKLNGSVFDDLYSGEKSICFFVHHGKCYWVLDHKYNFSLDAERDFKAHLDKGNISKEQYALACENFRGGVLRLNSESFLKYLELNSDVIVSRVDLEAVLNFDGIGNVLSLLNAAEKYFLSGVDLSAYDFQAAGIFSSRLPMFYVNFDREIYMHLDHGRFHEDLVYPGWVAKVFDFNFLIPEKEKYWINGGDCWKIRFIQSGF
>NZ_CP022263.1|WP_089112541.1|3293194_3293446_-|hypothetical-protein
MVGRANGGASSIQVATGTNGTAGAQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTNVQTTAAAVSSPVKQTLQK
>NZ_CP022263.1|WP_089112540.1|3291310_3291811_-|tryptophan-rich-sensory-protein
MTQHRLNTSQWFGLLGWLLLCYAVAALGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVVQLALNGLWSWLFFAWHLGAWAFADIVALWLVLAATIGAFAKKQTLAAWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP022263.1|WP_007963907.1|3288133_3290641_-|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP022263.1|WP_167382366.1|3287117_3288092_-|homoserine-kinase
MVQAQAQGSDHASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHNALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG
>NZ_CP022263.1|WP_089112548.1|3321627_3323328_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREDADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVANADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGDSHDLATRNEERGTRGNSLSYSLPWGWWTFALAASSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGGRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPVYGARVIYQF
>NZ_CP022263.1|WP_089112549.1|3324059_3326018_+|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGPDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPEYPDDAGLQRLGASLERQRGWQVHLSHAWGHSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDEWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGPAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDETRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQREQQLGLDLDFRWGGTP
>NZ_CP022263.1|WP_089112550.1|3325999_3327898_+|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRVFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRWRIETDLRHSRDAVVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQIDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQLPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP022263.1|WP_046832236.1|3327901_3329155_+|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP022263.1|WP_022559030.1|3329151_3329598_+|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVNADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR
>NZ_CP022263.1|WP_022559029.1|3330170_3331703_+|aldehyde-dehydrogenase-family-protein
MSADLLKALDLAASNSGTYLGEATWSQATGAGVLQPLNPATNAVIAEVQATTPEDYELIVQRAQAAFKVWRTTPAPRRGEAVRLCGEALRAHKDALGSLVALEMGKSKPEGDGEVQEMIDIADFAVGQSRMLYGYTMHSERPGHRMYEQYQPLGLVGIISAFNFPVAVWAWNAFLAAICGDICIWKPSNKTPLTAIATMKICNAALKDAGFPDIFFLINDAGTALSEKLVEDTRVPLISFTGSTQIGRVVAEKVARRLGRCLLELGGNNAIILDETADLKLAIPGIVFGAVGTAGQRCTTTRRLIVHASIYDTVLATLVKAYKQLDSKIGDPTDPANLMGPLNSQGAVAQFLDSIAKAKAAGGTVEVGGTAIDRPGNFVLPAIVTGLQNSDAVVQHETFAPILYVMKYSTLDEAIELQNGVPQGLSSSIFTQNLKAAEKFLSAAGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKVYMRRQTNTINYSDSLPLAQGIRFDL
>NZ_CP022263.1|WP_157768143.1|3331870_3332080_-|hypothetical-protein
MRFALATLSFAGRQLLLQSKLRVVAGRGFVQQRQAFGFTSTRIRSRSQSLSACIRMSSQHGCIAKGRAG
>NZ_CP022263.1|WP_026007260.1|3332284_3332569_+|DUF4190-domain-containing-protein
MNVVVRQTSAMAIVSLVAGILGWTLIPFLGSICAIITGHLARAEIRRNPQALDGDGLAIGGLIMGWLAVALWIVGIAFFLLFFGGMAWLAAANS
>NZ_CP022263.1|WP_167382307.1|3332571_3333339_+|class-I-SAM-dependent-methyltransferase
MATPSSAQRFNDRVAAYVRYRPSYPPQLLRWLHGELGVTPATAVTDIGAGTGISSRLFLEAGYAVTAVEPNQAMREAALQWLAEYPKFQAIAGTAEATGLGDASVGLVSAAQAFHWFDMQAVRDEWARILQPGGLAVVYWNSRELDSTAFLRGYEQLLLDFGTDYSAVAERYQDDATMQAWFGEGFRAMARFPNVQRLDFESLRGRLLSSSYAPLAHDPRHAPMLAALRTLFDAYAYDGLIDFQYQTRVFAGRLN
>NZ_CP022263.1|WP_007965740.1|3333344_3334400_+|quinone-dependent-dihydroorotate-dehydrogenase
MYSLARPFLFSLDAERAHALALRSIDTAYRTGTTALLARRPVPLPTPAFGLMFPNPVGLGAGLDKNGEHIDALFALGFGFVEIGTVTPRAQEGNPKPRMFRLPEYQAVINRMGFNNLGVDALVANVQRARRTAGLLGINIGKNKDTPNEEATSDYRYCMERVYPLADYITVNISSPNTAGLRELQEEQSLRRLISDLRETQEALSAQHGKRVPMLVKVAPDLNDRDIDAAARVLADLAVDGVIATNTTVTRTLVANHPLAAEAGGLSGAPLLGQSTLVLRRLRARLPESIPLIGVGGINSGADAVAKMAAGASLVQCYSGLVYRGPQLIGECVNAIRRRREAPSGGAVSPL

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Crispr_ID: NZ_CP022263_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022263_7

5285121-5285221

Orphan

Consensus_repeat	Method
GTGCAGGTGCGTCCTTCGGCCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022263_7

>merge|NZ_CP022263|7|5285121-5285221|CRISPRCasFinder
GTCCAGGTGCGTCCGGCCGCCGACCAGATCGCCCAGCAGACCCTGGAACGCACCAGCGACATCCGCACCCTGGCCGCCGTGCAGGTGCGTCCTTCGGCCGA

>NZ_CP022263|7|7|5285121-5285221|CRISPRCasFinder
GTCCAGGTGCGTCCGGCCGCCGA	CCAGATCGCCCAGCAGACCCTGGAACGCACCAGCGACATCCGCACCCTGGCCGCC
GTGCAGGTGCGTCCTTCGGCCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022263.1\|WP_007974735.1\|5295290_5296316_-\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NZ_CP022263.1\|WP_022557907.1\|5288377_5289130_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_007966372.1\|5284311_5284632_-\|DUF4156-domain-containing-protein	unknown	unknown	gnl\|CDD\|372679
NZ_CP022263.1\|WP_089113366.1\|5287657_5288275_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022263.1\|WP_167382372.1\|5281912_5282995_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NZ_CP022263.1\|WP_003488520.1\|5294226_5294823_+\|Ax21-family-protein	unknown	unknown	gnl\|CDD\|275096
NZ_CP022263.1\|WP_003468167.1\|5274089_5274248_-\|DUF1328-domain-containing-protein	unknown	unknown	gnl\|CDD\|227774
NZ_CP022263.1\|WP_089113362.1\|5276893_5278441_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|294013
NZ_CP022263.1\|WP_003488348.1\|5285506_5285983_+\|tRNA-(cytidine(34)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|349967
NZ_CP022263.1\|WP_003488515.1\|5296331_5296844_-\|protein-export-chaperone-SecB	unknown	unknown	gnl\|CDD\|180234
NZ_CP022263.1\|WP_007972046.1\|5274312_5275323_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187552
NZ_CP022263.1\|WP_089113368.1\|5290651_5292094_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP022263.1\|WP_089113369.1\|5292143_5293871_-\|ubiquinone-dependent-pyruvate-dehydrogenase	unknown	unknown	gnl\|CDD\|181661
NZ_CP022263.1\|WP_089113367.1\|5289320_5290667_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP022263.1\|WP_089113365.1\|5286335_5287565_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP022263.1\|WP_007972041.1\|5280348_5280732_+\|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|223799
NZ_CP022263.1\|WP_089113363.1\|5280884_5281787_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|179147
NZ_CP022263.1\|WP_005912222.1\|5283193_5284210_-\|3-oxoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|181732
NZ_CP022263.1\|WP_089113647.1\|5278449_5280105_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236443
NZ_CP022263.1\|WP_089113361.1\|5275521_5276694_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|224594

Protein	Function_ID	Function_description	E-value
NZ_CP022263.1\|WP_089113368.1\|5290651_5292094_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.44305e-32
NZ_CP022263.1\|WP_007966372.1\|5284311_5284632_-\|DUF4156-domain-containing-protein	gnl\|CDD\|372679	pfam13698, DUF4156, Domain of unknown function (DUF4156). The function of this family is unknown but members are annotated as putative lipoprotein outer membrane proteins.	1.76533e-09
NZ_CP022263.1\|WP_167382372.1\|5281912_5282995_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	5.04412e-63
NZ_CP022263.1\|WP_003488520.1\|5294226_5294823_+\|Ax21-family-protein	gnl\|CDD\|275096	TIGR04273, activator_of_XA21-mediated_immunity_Ax21, sulfation-dependent quorum factor, Ax21 family. This family consists of proteins closely related to Ax21 (Activator of XA21-mediated immunity), a protein that is secreted by a type I secretion system (RaxABC), and that appears to be sulfated on an N-terminal region tryosine in a motif LSYN. Ax21 acts in a quorum-sensing system. Homologous peptide-mediated quorum-sensing systems appear to exist in other species, such as the emerging opportunistic pathogen Stenotrophomonas maltophilia. Intriguingly, the rice genome encodes a receptor (XA21) for this protein that triggers innate immunity. [Cellular processes, Pathogenesis].	3.12215e-108
NZ_CP022263.1\|WP_003468167.1\|5274089_5274248_-\|DUF1328-domain-containing-protein	gnl\|CDD\|227774	COG5487, COG5487, Small integral membrane protein [Function unknown].	0.00222793
NZ_CP022263.1\|WP_089113362.1\|5276893_5278441_-\|transcriptional-regulator	gnl\|CDD\|294013	cd00383, trans_reg_C, DNA-binding effector domain of two-component system response regulators. Bacteria and some eukaryotes use two-component signal transduction systems to detect and respond to changes in the environment. The systems consists of a sensor histidine kinase and a response regulator. The former autophosphorylates a histidine residue on detecting an external stimulus. The phosphate is then transferred to an invariant aspartate residue in a highly conserved receiver domain of the response regulator. Phosphorylation activates a variable effector domain of the response regulator, which triggers the cellular response. This C-terminal effector domain belongs to the winged helix-turn-helix family of transcriptional regulators and contains DNA and RNA polymerase binding sites. Several dimers or monomers bind head to tail to small tandem repeats upstream of the genes. The RNA polymerase binding sites interact with the alpha or sigma subunit of RNA polymerase.	6.58518e-20
NZ_CP022263.1\|WP_003488348.1\|5285506_5285983_+\|tRNA-(cytidine(34)-2'-O)-methyltransferase	gnl\|CDD\|349967	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL. tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	2.47465e-81
NZ_CP022263.1\|WP_003488515.1\|5296331_5296844_-\|protein-export-chaperone-SecB	gnl\|CDD\|180234	PRK05751, PRK05751, preprotein translocase subunit SecB; Validated.	3.40232e-69
NZ_CP022263.1\|WP_007972046.1\|5274312_5275323_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187552	cd05241, 3b-HSD-like_SDR_e, 3beta-hydroxysteroid dehydrogenases (3b-HSD)-like, extended (e) SDRs. Extended SDR family domains belonging to this subgroup have the characteristic active site tetrad and a fairly well-conserved NAD(P)-binding motif. 3b-HSD catalyzes the NAD-dependent conversion of various steroids, such as pregnenolone to progesterone, or androstenediol to testosterone. This subgroup includes an unusual bifunctional 3b-HSD/C-4 decarboxylase from Arabidopsis thaliana, and Saccharomyces cerevisiae ERG26, a 3b-HSD/C-4 decarboxylase, involved in the synthesis of ergosterol, the major sterol of yeast. It also includes human 3 beta-HSD/HSD3B1 and C(27) 3beta-HSD/ [3beta-hydroxy-delta(5)-C(27)-steroid oxidoreductase; HSD3B7]. C(27) 3beta-HSD/HSD3B7 is a membrane-bound enzyme of the endoplasmic reticulum, that catalyzes the isomerization and oxidation of 7alpha-hydroxylated sterol intermediates, an early step in bile acid biosynthesis. Mutations in the human NSDHL (NAD(P)H steroid dehydrogenase-like protein) cause CHILD syndrome (congenital hemidysplasia with ichthyosiform nevus and limb defects), an X-linked dominant, male-lethal trait. Mutations in the human gene encoding C(27) 3beta-HSD underlie a rare autosomal recessive form of neonatal cholestasis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid sythase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.51368e-82
NZ_CP022263.1\|WP_007974735.1\|5295290_5296316_-\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	4.57783e-180
NZ_CP022263.1\|WP_089113369.1\|5292143_5293871_-\|ubiquinone-dependent-pyruvate-dehydrogenase	gnl\|CDD\|181661	PRK09124, PRK09124, ubiquinone-dependent pyruvate dehydrogenase.	0
NZ_CP022263.1\|WP_089113367.1\|5289320_5290667_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.60216e-174
NZ_CP022263.1\|WP_089113365.1\|5286335_5287565_-\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.91729e-20
NZ_CP022263.1\|WP_007972041.1\|5280348_5280732_+\|YkgJ-family-cysteine-cluster-protein	gnl\|CDD\|223799	COG0727, COG0727, Predicted Fe-S-cluster oxidoreductase [General function prediction only].	2.27067e-20
NZ_CP022263.1\|WP_089113363.1\|5280884_5281787_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|179147	PRK00870, PRK00870, haloalkane dehalogenase; Provisional.	5.74527e-48
NZ_CP022263.1\|WP_005912222.1\|5283193_5284210_-\|3-oxoacyl-ACP-synthase-III	gnl\|CDD\|181732	PRK09258, PRK09258, 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed.	0
NZ_CP022263.1\|WP_089113647.1\|5278449_5280105_-\|AMP-binding-protein	gnl\|CDD\|236443	PRK09274, PRK09274, peptide synthase; Provisional.	0
NZ_CP022263.1\|WP_089113361.1\|5275521_5276694_+\|serine-hydrolase	gnl\|CDD\|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	1.71877e-32

>NZ_CP022263.1|WP_007966372.1|5284311_5284632_-|DUF4156-domain-containing-protein
MRVLMLSVLVATTTAACTWVPIEQSGKGVRVLPAGPVPAGCQQQGEVVVTVKSKVGFYNRNPLRVQEELETLARNEAPGANANAVQAQGQPADGSQRFNAFRCPPR
>NZ_CP022263.1|WP_005912222.1|5283193_5284210_-|3-oxoacyl-ACP-synthase-III
MLFQNVSIAGLAHVDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQASDAATQAARKALIDAGIGIEKIGLLVNTSVSRDYLEPSTASIVSGNLGVGDHCVTFDVANACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKTLERMTSPDVTEEEFRNELAALTLGCGAAAMVMARTELVPDAPRYKGGVTRSATEWNKLCRGNLDRMVTDTRLLLIEGIKLAQKTFMAARQVLGWAVDELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPASVPIVLSKLKELGRLKKGDRIALLGIGSGLNCSMAEVVW
>NZ_CP022263.1|WP_167382372.1|5281912_5282995_-|Fic-family-protein
MPALDFAQVELVARKERADQALGRFEGITLMLPDPELLLYQDVRKEALLSSQIEGAQSSLSDLLLFEMDAAPGIPMDDVEEASNYVAALNHGLRRLREDDFPLSLRLIREMHALLLQGGRGASKQPGEFRRSQVWVGGASPALAHFVPPPPDAVPGTLAALEQFLHAPPGQIPPLVKAALAHVQFETIHPFSDGHGRLGRLLITLILCSEGVLREPSLYLSLYFKRRRADYYDRLNAVRLNGDWEGWLGFFLDGVAETAQQAVDAAQRLLALLARDRARIAALGKRVGNVGLVFEQFARRVVLAVPQVAPHLSLSVPTIRAAVRTLQELKIVNKLTGQQRHRIFAYQAYLDILSEGAQPL
>NZ_CP022263.1|WP_089113363.1|5280884_5281787_-|alpha/beta-fold-hydrolase
MNYPGYPFTPKRLDVRPGVAMSYLDEGPRDGEVVVMLHGNPSWSYLWRHLVSGLSDRYRCIVPDHIGMGLSDKPDDAPDAQPRYDYTLQSRVDDLDSLLRHLGITGAVTLAVHDWGGMIGFGWALSHHAQVKRLVITNTAAFPLPAEKPMPWQIAMGRHWRPGEWFIRTFNAFSSGASWLGVSRRMPSEVRRAYVAPYNNWRNRISTIRFMQDIPLSPADKGWSLLERSAQALASFADRPAFIAWGLRDICFDKYFLAGFRKALPQAEVTAFDDANHYVLEDKHEVLVPAIRAFLERNPL
>NZ_CP022263.1|WP_007972041.1|5280348_5280732_+|YkgJ-family-cysteine-cluster-protein
MAHPCLTCGACCAYFRVSFHWSEADPALGGRVPIELTEALRTHERVMRGTSQSQPRCIALDAEIGRYSRCSIHDRRPSSCAAVPASLEFGERSAQCDKSRLAHGLHALTDADWVGVDDAQRNPLPPV
>NZ_CP022263.1|WP_089113647.1|5278449_5280105_-|AMP-binding-protein
MTTLCNIAATLPQLARERPDQIAIRCPGGRGANGFAAYDVTLSYAELDARSDAIAAGLARHGIGRGARAVVMVRPSPEFFLLMFALFKAGAVPVLVDPGIDKRALKQCLDEAQPQAFIGIALAQLARRLLRWARSAKQIVTVGGRYGWGGVTLARVERDGAGAGAGSQLADTGPDDVAAILFTSGSTGVPKGVVYRHRHFVGQIELLRNAFGMQPGGVDLPTFPPFALFDPALGLTSVIPDMDPTRPGSADPRKLHDAINRFGVTQLFGSPALMRVLADYGQPLPDVRLATSAGAPVPPDVVAKIRALLPADAQFWTPYGATECLPVAAIEGRTLDATRAATEAGAGTCVGQVVAPNEVRIIAIDDAAIADWSGVRVLATGEVGEIAVAGPTATDTYFNRDAATRIAKIRERCSDGSERVVHRMGDVGYFDAEGRLWFCGRKTHRVEAASGPLYTEQVEPVFNVHPQVRRTALVGVGAPGQQQPVLCVELQPGVSASAFAQVESDLRALGAAHPHTAGVARFLRHSGFPVDIRHNAKIGRETLAVWATQQR
>NZ_CP022263.1|WP_089113362.1|5276893_5278441_-|transcriptional-regulator
MRARYRLDDLRIDIARQRVERDGVALEVTGLSFRLLHYLLQQGQRVVDFDELIQHVWAPALVNEETVTQRVRLLRQALGDDSRQPRYLRSVRGQGYQLCVPVQQEQVPPAMRRHYAWPVAAVAALVCIGAGVIGWLQTRDAPPAAAALVQRAAYYAGIGQRDDNDRAIDLYGQRLQQAPDDRQAQLGLSRAYSARVCQYDGDAAYAARALQLANGVVTAQPDLAAAHAARGYALDCQGRNADALAAYEHALQLDADADAVRGSAAYLYERRGKLVQALTANLAVRDPTRVRFLPIQIASNLSLLGYAGAAETRYRKNFQLYPDDPFSNLAWPTFLFEHGRAAEAETALNASLNRGTAYAGLSVLQAELAWARGDESLARQAALHAIQLRPQGSFAQTVAWAVHAQPPPAPAVLRMRAQELLNSVERGGDPFDAIDAAVLLLCAEAPEAAMRAVQRAEAAGYRNAGYLRQSPLLKPLRRSPEFIALLARIDADLAAQRAQLRRRNLLPTDAVSGSN
>NZ_CP022263.1|WP_089113361.1|5275521_5276694_+|serine-hydrolase
MCRPSLLLSALLAASALHAAPPIAASPATTPTAAGPAKATLPPATPLVLGDGWPVASVATSGWNLTLLAQMEQALADDLAPSTTSVLIVRDGVLVYEKYLGDATRETLHDTRSLTKSVTALLVGAAIERKLLPSAQAKVFDYFGDRQWQHPDPRKRAITVEDLLTMSSQLECNDDNEFSAGNEERMYLSADWTQFALDLPIRGYAPWMQRPEHSPYGRAFSYCTAGSFLLGALLEKATGQPLRAFAGEVLETPLGIKNVQWTVSSEGVGMGGGGNRYRSRDLAKLGQLLVAQGRWQGRQVIPADWIGAMTRVQAQAREDADYGYLTWHFRFPVHGVQRDTWAMSGNGGNYVFVVPAERLVVVLTRSAYNTRQMHQQSHRVLTDYVLKALP
>NZ_CP022263.1|WP_007972046.1|5274312_5275323_-|NAD-dependent-epimerase/dehydratase-family-protein
MKVLVTGGGGFLGQALCRGLRARGHEVVSFQRGDYPVLQRLGVGQIRGDLADPQAVRHAFAGIDAVFHNAAKAGAWGSYDSYHQANVVGTQNVIEACRANGVPRLIYTSTPSVTHRATNPVEGLGADEVPYGDDLRAAYAATKAIAERAVLAANDAQLATVALRPRLIWGPGDNHLLPRLAARARAGRLRMVGDGGNLVDSTYIDNAAQAHFDAFQHLAVGAACAGKAYFISNGEPLPMRELLNRLLAAVDAPAVTRSLSFNTAYRIGAVCETLWPLLRLPGEVPLTRFLVEQLCTPHWYSMEPARRDFGYVPRISIEEGLQRLRSSSSNDIAITR
>NZ_CP022263.1|WP_003468167.1|5274089_5274248_-|DUF1328-domain-containing-protein
MLHYAIIFFVIAIIAAVLGFSGIAGAATNIAWILFVVFLILAVISMFRRGKV
>NZ_CP022263.1|WP_003488348.1|5285506_5285983_+|tRNA-(cytidine(34)-2'-O)-methyltransferase
MSAPVLDVILFQPEIPPNTGNVIRLCANTGARLHLIEPLGFDLSDKQLKRAGLDYHEYAPLQVHADLPSALAAIAPKRVFALSTRSTVRYDTPQFADGDAFLFGPETRGLPAEVLESIPPQHRLRLPMRPDNRSLNLSNTVAVMVFEAWRQWNFAGGQ
>NZ_CP022263.1|WP_089113365.1|5286335_5287565_-|MFS-transporter
MPMTKARPRGTRALEALHFSVADVQDGLGPFLSVFLQSKGWSVAAIGTVMSVGGIAGMLATTPAGALVDATRRKRAVVVIGCLAILLATALIWLQPTSSGVVAAQIASALAAAGIGPALTGITLGLVHARGFDHQLARNQVANHAGNVLAAVLAGWLGWRYGFAAVFLLTAFFGALALMAVLAIPAAAIDHRAARGLASNNGGDALSGWRVLLTCRPLALLAVTLGLFHLGNAAMLPLYGMAIVAAHAGDPSALTATTIVVAQATMVVVALLAMRWIRVHGHWWVLLVAFMALPLRALVAASVIHGWGVFPVQILDGLGAGLQSVVVPALVARLLQGTGRVNVGQGAVMTVQGVGAALSPAFGGWLAHAFGYRIAFLSLGAIALLAVALWAGCRGMLQAGASVQAETML
>NZ_CP022263.1|WP_089113366.1|5287657_5288275_-|hypothetical-protein
MHWVDPDFLPATRGTLARFLLNPKADIDGLLLTDGTEVHTPPHLSEALLKALKPGSALTVRGLKPRDVEMLVALAIDPEGGKRILDEGPHGPHAKPKPKPPGKPTKPEVAQHSGTITRLLHGPHGQVHGVLLDDAVTVRFPPHAGGDFAKQLVVGKPLVAEGETKATPHGVLIHAHALGGKAATLKQIEHPPHGPAHKPKPKPKH
>NZ_CP022263.1|WP_022557907.1|5288377_5289130_-|hypothetical-protein
MMRQTVLAIALACTIGAAAAQVAAPPPPPAPNGPIGGPPAPPTPVAATPVSVSGTVERFLLNPNGDVDGLWLRDGTQVGFPPHLSSEVKAAVRAGDSVVVKGFRLGNLPVLQVSSIRSGRSGREVVDRPPTFGAAPPPPPTPGQLTPLQSDGTIHRLVYGPAGEVNGALVSDGTVVRMPPHLALQFADLLRVGAPLSASGLGVATPDGRAIEATQLGRDRSSLRALFTAPRPDGPLPPPPPGAPVPPAGR
>NZ_CP022263.1|WP_089113367.1|5289320_5290667_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MARILIIDDDAAFRTTLQATLRSLGHTAVAAENGPDGLARLSEGGIDMAFVDFRMPGMDGIAVLRARLDDAQARQVPLVMLTAHVSSGNTIEAMTLGAFDHLVKPVGRADIVEVVERALLGRADAQAAATDALSAPAEDDDALVGHSPAMRTVHKRIGLAAASDLPVLITGETGTGKELAARALHRASPRARAPFVAVNCAAIPLELMESELFGHRKGAFSGASSDRRGLIREADGGTLFLDEIGDMPLPMQAKLLRFLQEGEVTPLGGSGPQKVDVRVLAATHRDLAACVADGRFRSDLRYRLNVVPIELPPLRERGQDILLLAQHFLSANAAHAQSLSPAAQERLLAHRWPGNVRELRNVMQRSQVLVRGASIDAADLEEALGEAGEAPPNVASALTGTLPEAVAQLEKQMIQSALEQSQGNRAEAARRLGIHRQLLYRKLEEYGL
>NZ_CP022263.1|WP_089113368.1|5290651_5292094_-|HAMP-domain-containing-histidine-kinase
MPRSLLRQLLLIWMVIVAACLGVATMLYGLYRQTEGVRLEEARQQLGGQCARIVQRYAGASEAARRGDDGVGLAAVVVQLVLADAPGVEGGVWDLHKGFVAYAYPTYDGSDHKTDIPAAEWANIVNTAQQSVTTKQAAQYRRDGRREVLLISACPLASGSAAWTMTRVPASKADAWRPLVVGMLLIFAMVAISAIALGVLVRRWSQRLQRIQQALAADTETPHIPPTGTPELDRLGAAVNDYAQRNAQALAQTRRLADELSRHERLAALGRMTATVAHEIRNPIATMRLALENEIARDDATPDDAAHGELMLGQIRRLDGVVESLLGMVQPIRLHLETVVVQDWLATLLEPSPLPPGTPPPRVLLPAAPLRWTLDPQQLGRAVHNLLRNAAQHADPGSEVTLQAEAVEGILQLQVCNRGAPIAEPIAAHLFEPFVSGRPDGNGLGLALVREIARAHGGHARYAHADGLTHFILELPWRAS
>NZ_CP022263.1|WP_089113369.1|5292143_5293871_-|ubiquinone-dependent-pyruvate-dehydrogenase
MAKKRTLARFLAETLQGAGVERIWGVTGDSLNGLTDALREMQTIEWMHVRHEEVAAFAAGAEAAVTGELAVCAGSCGPGNLHLINGLFDCHRSRQPVLAIAAHIPSSEIGLSYFQETHPQELFRECSHFVELVTNPAQLPEVLHRAMRSAILQQGVAVVVIPGDIALLEVDKHVSSAWPALRQPRVLPAAEDVQQLAELLQQSKAVTVLCGSGCAGAHDAVVALADTLGAPVVHALRGKEYVEWDNPFDVGMTGLIGFSSGYHAMLNCDTLLMLGTDFPYRQFYPKDATIVQVDRDPSALGRRTPLQLGIAADVGETIAALLPQLQRREERGFLEKSLAHYRKAREGLDDLAVPADPGEPLHPQFVTRLISQIADQDAVFTCDVGTPTVWAARYLRMNGKRRLLGSFNHGSMANAMPQALGAQAAFPGRQVISLSGDGGSAMLMGDFISLAQLNLPVKVVVFNNASLGFVAMEMKAAGYLDTGTELRNPDFAAMSNAMGILGIRVDESSQLERALRQAFAHSGPALVDVRVATQELAVPPAIKLEQAKGMGLYLLKAVMSGRGDEVIALVKTNLR
>NZ_CP022263.1|WP_003488520.1|5294226_5294823_+|Ax21-family-protein
MKTSLLALGLLAALPFAASAAENLSYNFVEGDYVRTPTEGRDADGWGVKASYAIAPNFHVFGDYSKQNADDNNNVFENTDSDFQQWGVGVGFNHEIATSTDFVARVAYRKLDLDTPNINFDGYSVEAGLRNAFGEHFEVYALAGYEDFSKKRGIDIGDNFYGRLGAQVKLNQNWGINGDIRMDGDGNKEWSVGPRFSW
>NZ_CP022263.1|WP_007974735.1|5295290_5296316_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MSDLTHKIAVLGAGSWGTALAALLARHGHPTVLWGRDAAMVDTIDRTHENARYLPGIALPDSLRATTDLQAAVADATWILVVVPSHAFTETIRLIAPLRPAGAGVAWATKGFEPGSGRFLHEVARDILGPSVPLAVVTGPSFAKEVTLGLPTAITVHGDDAAFAQVVADAMHGPTFRAYTGDDMVGAELGGAMKNVLAVATGVADGMQLGLNARAGLITRGLNEMLRLAAVIGARPETLMGLAGLGDLVLTCTGDLSRNRRLGLALGRGQSLDEAIREIGQVVESVQTADEVMRQAEHHGIELPISNAVRAVLHGEITPEAGLKELLARERKPEYPQTLFT
>NZ_CP022263.1|WP_003488515.1|5296331_5296844_-|protein-export-chaperone-SecB
MSDEILNGAAAPADAAAGPAFTIEKIYVKDVSFESPNAPAVFNDANQPELQLNLNQKVQRLNDNAFEVVLAVTLTCTAGGKTAYVAEVQQAGVFGLVGLDPQAIDVLLGTQCPNILFPYVRTLVSDLIQAGGFPPFYLQPINFEALYAETLRQRQNEGTSLADSEPAGNA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP022263_4	4.1\|3298311\|40\|NZ_CP022263\|CRISPRCasFinder	3298311-3298350	40	NZ_CP022263.1	3303863-3303902	2	0.95
NZ_CP022263_6	6.1\|3311021\|40\|NZ_CP022263\|CRISPRCasFinder	3311021-3311060	40	NZ_CP022263.1	3303863-3303902	2	0.95

1. spacer 4.1|3298311|40|NZ_CP022263|CRISPRCasFinder matches to position: 3303863-3303902, mismatch: 2, identity: 0.95

tccccaagcctttgcctgcatcgagctttgcggcgaccag	CRISPR spacer
tccccaagcccttgcctgcatcgagctttgcggcaaccag	Protospacer
**********.***********************.*****

2. spacer 6.1|3311021|40|NZ_CP022263|CRISPRCasFinder matches to position: 3303863-3303902, mismatch: 2, identity: 0.95

tccccaagcctttgcctgcatcgagctttgcggcgaccag	CRISPR spacer
tccccaagcccttgcctgcatcgagctttgcggcaaccag	Protospacer
**********.***********************.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	841349-841379	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	841095-841125	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	741214-741244	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	811280-811310	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	740329-740359	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	742907-742937	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	742896-742926	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	741201-741231	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	741220-741250	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	741198-741228	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	841418-841448	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	841417-841447	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	841402-841432	6	0.806
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	463181-463214	6	0.824
NZ_CP022263_1	1.15\|29371\|31\|NZ_CP022263\|CRISPRCasFinder	29371-29401	31	NC_009806	Kineococcus radiotolerans SRS30216 = ATCC BAA-149 plasmid pKRAD01, complete sequence	119514-119544	6	0.806
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	513842-513872	7	0.774
NZ_CP022263_1	1.12\|29203\|31\|NZ_CP022263\|CRISPRCasFinder	29203-29233	31	NZ_CP015279	Mycobacterium chimaera strain DSM 44623 plasmid unnamed 1, complete sequence	150331-150361	7	0.774
NZ_CP022263_1	1.12\|29203\|31\|NZ_CP022263\|CRISPRCasFinder	29203-29233	31	NZ_CP015280	Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence	81610-81640	7	0.774
NZ_CP022263_1	1.14\|29314\|34\|NZ_CP022263\|CRISPRCasFinder	29314-29347	34	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1614842-1614875	7	0.794
NZ_CP022263_1	1.15\|29371\|31\|NZ_CP022263\|CRISPRCasFinder	29371-29401	31	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	322116-322146	7	0.774
NZ_CP022263_1	1.15\|29371\|31\|NZ_CP022263\|CRISPRCasFinder	29371-29401	31	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	23696-23726	7	0.774
NZ_CP022263_1	1.15\|29371\|31\|NZ_CP022263\|CRISPRCasFinder	29371-29401	31	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	135212-135242	7	0.774
NZ_CP022263_1	1.15\|29371\|31\|NZ_CP022263\|CRISPRCasFinder	29371-29401	31	NC_008384	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence	475100-475130	8	0.742
NZ_CP022263_1	1.11\|29149\|31\|NZ_CP022263\|CRISPRCasFinder	29149-29179	31	NZ_CP013739	Streptomyces globisporus C-1027 plasmid SGLP1, complete sequence	114529-114559	9	0.71
NZ_CP022263_1	1.12\|29203\|31\|NZ_CP022263\|CRISPRCasFinder	29203-29233	31	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	934481-934511	9	0.71
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NC_015179	Acidiphilium multivorum AIU301 plasmid pACMV3, complete sequence	32207-32240	9	0.735
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	657714-657747	9	0.735
NZ_CP022263_1	1.4\|29251\|39\|NZ_CP022263\|CRT	29251-29289	39	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	463182-463220	10	0.744
NZ_CP022263_1	1.9\|29251\|40\|NZ_CP022263\|PILER-CR	29251-29290	40	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	463181-463220	10	0.75
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	367183-367216	10	0.706
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	138043-138076	10	0.706
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NZ_CP030128	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence	345663-345696	10	0.706
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	AF440695	Virus PhiCh1, complete genome	58189-58222	10	0.706
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NC_004084	Natrialba phage PhiCh1, complete genome	58189-58222	10	0.706
NZ_CP022263_1	1.14\|29314\|34\|NZ_CP022263\|CRISPRCasFinder	29314-29347	34	MH271303	Microbacterium phage MementoMori, complete genome	20739-20772	10	0.706
NZ_CP022263_1	1.14\|29314\|34\|NZ_CP022263\|CRISPRCasFinder	29314-29347	34	MN813682	Microbacterium phage Matzah, complete genome	21015-21048	10	0.706
NZ_CP022263_1	1.14\|29314\|34\|NZ_CP022263\|CRISPRCasFinder	29314-29347	34	MK937591	Microbacterium phage Cinna, complete genome	21039-21072	10	0.706
NZ_CP022263_1	1.13\|29257\|34\|NZ_CP022263\|CRISPRCasFinder	29257-29290	34	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	486064-486097	11	0.676
NZ_CP022263_1	1.14\|29314\|34\|NZ_CP022263\|CRISPRCasFinder	29314-29347	34	NZ_AP012556	Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence	22147-22180	11	0.676
NZ_CP022263_1	1.14\|29314\|34\|NZ_CP022263\|CRISPRCasFinder	29314-29347	34	NC_016588	Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence	72444-72477	11	0.676
NZ_CP022263_1	1.14\|29314\|34\|NZ_CP022263\|CRISPRCasFinder	29314-29347	34	NZ_CP023152	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence	116465-116498	11	0.676

1. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

2. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

3. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

4. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

5. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

6. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

7. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

8. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

9. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

10. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

11. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

12. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

13. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.806

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gagaccggtgccggcgcgcaaacctacgatg	Protospacer
****.*********.********* * .*.*

14. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 6, identity: 0.824

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
tcgctgggcctgaaggcgatcgtgtccggcccgc	Protospacer
 ********* *****.*************  .*

15. spacer 1.15|29371|31|NZ_CP022263|CRISPRCasFinder matches to NC_009806 (Kineococcus radiotolerans SRS30216 = ATCC BAA-149 plasmid pKRAD01, complete sequence) position: , mismatch: 6, identity: 0.806

gggctggtggggaccgagctcggcaagggca	CRISPR spacer
cggctggtggggaccggtctcggcaacgtcg	Protospacer
 ***************. ******** * *.

16. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 7, identity: 0.774

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
gcattgggtgccggtgcgcaagccaacaaca	Protospacer
* . * ***************.**** ***.

17. spacer 1.12|29203|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP015279 (Mycobacterium chimaera strain DSM 44623 plasmid unnamed 1, complete sequence) position: , mismatch: 7, identity: 0.774

cgcatcggcgacaacgcgcgtaccgggggcg	CRISPR spacer
atcaccggcgacaacgcgcgcaccgccgccg	Protospacer
  **.***************.****  * **

18. spacer 1.12|29203|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP015280 (Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence) position: , mismatch: 7, identity: 0.774

cgcatcggcgacaacgcgcgtaccgggggcg	CRISPR spacer
atcaccggcgacaacgcgcgcaccgccgccg	Protospacer
  **.***************.****  * **

19. spacer 1.14|29314|34|NZ_CP022263|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

ctcgccgagcgcggcagccagatcagtggcgggg	CRISPR spacer
ttcgtcgagcgcggcagccagatcatggggctgg	Protospacer
.***.********************  **   **

20. spacer 1.15|29371|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.774

gggctggtggggaccgagctcggcaagggca	CRISPR spacer
gtgctggcggggaccgggctcggcatcgtcc	Protospacer
* *****.********.********  * *

21. spacer 1.15|29371|31|NZ_CP022263|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 7, identity: 0.774

gggctggtggggaccgagctcggcaagggca	CRISPR spacer
gtgctggcggggaccgggctcggcatcgtcc	Protospacer
* *****.********.********  * *

22. spacer 1.15|29371|31|NZ_CP022263|CRISPRCasFinder matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 7, identity: 0.774

gggctggtggggaccgagctcggcaagggca	CRISPR spacer
gtgctggcggggaccgggctcggcatcgtcc	Protospacer
* *****.********.********  * *

23. spacer 1.15|29371|31|NZ_CP022263|CRISPRCasFinder matches to NC_008384 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL11, complete sequence) position: , mismatch: 8, identity: 0.742

gggctggtggggaccgagctcggcaagggca	CRISPR spacer
agcgcgctggcggccgagctcggcaagggcg	Protospacer
.*  .* *** *.*****************.

24. spacer 1.11|29149|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP013739 (Streptomyces globisporus C-1027 plasmid SGLP1, complete sequence) position: , mismatch: 9, identity: 0.71

gagatcggtgccggtgcgcaaaccaagaacg	CRISPR spacer
cagagcggtgccggtgcgcatacctctgggg	Protospacer
 *** *************** ***   .. *

25. spacer 1.12|29203|31|NZ_CP022263|CRISPRCasFinder matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 9, identity: 0.71

cgcatcggcgacaacgcgcgtaccgggggcg	CRISPR spacer
cgcagcggcgacaacgcgcgcaccatcttgc	Protospacer
**** ***************.***.

26. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NC_015179 (Acidiphilium multivorum AIU301 plasmid pACMV3, complete sequence) position: , mismatch: 9, identity: 0.735

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
aatgagggcgagaaggtgatcgagtccggcgaga	Protospacer
*    **** ************ ********..

27. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 9, identity: 0.735

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
tggatgggccagaaattgatcgtgtccggaaagc	Protospacer
  * **********. ************* ...*

28. spacer 1.4|29251|39|NZ_CP022263|CRT matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 10, identity: 0.744

tcgatcacgctgggccagaaggtgatcgtgtccggcgga	CRISPR spacer
cagcgctcgctgggcctgaaggcgatcgtgtccggcccg	Protospacer
. *  * ********* *****.*************  .

29. spacer 1.9|29251|40|NZ_CP022263|PILER-CR matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 10, identity: 0.75

tcgatcacgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
cagcgctcgctgggcctgaaggcgatcgtgtccggcccgc	Protospacer
. *  * ********* *****.*************  .*

30. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
aaagcgggccagaaggtggtcgtgtccggacagt	Protospacer
* . .*************.**********  ...

31. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 10, identity: 0.706

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
cccatcagccagaaggtgatcgtggccagcgtgt	Protospacer
 *  * .***************** **.*** ..

32. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NZ_CP030128 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
ttgcgcggccagaaggtgaccgtgtccagcctgt	Protospacer
 .**  *************.*******.**  ..

33. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to AF440695 (Virus PhiCh1, complete genome) position: , mismatch: 10, identity: 0.706

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
cagctggggcagacggtgatcgtgtcgcgaaggg	Protospacer
  ****** **** ************  * .*.

34. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NC_004084 (Natrialba phage PhiCh1, complete genome) position: , mismatch: 10, identity: 0.706

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
cagctggggcagacggtgatcgtgtcgcgaaggg	Protospacer
  ****** **** ************  * .*.

35. spacer 1.14|29314|34|NZ_CP022263|CRISPRCasFinder matches to MH271303 (Microbacterium phage MementoMori, complete genome) position: , mismatch: 10, identity: 0.706

ctcgccgagcgcggcagccagatcagtggcgggg	CRISPR spacer
ctcgccgagcgcggcatcccgatcctctccctgc	Protospacer
**************** ** ****  .  *  *

36. spacer 1.14|29314|34|NZ_CP022263|CRISPRCasFinder matches to MN813682 (Microbacterium phage Matzah, complete genome) position: , mismatch: 10, identity: 0.706

ctcgccgagcgcggcagccagatcagtggcgggg	CRISPR spacer
ctcgccgagcgcggcatcccgatcctctccctgc	Protospacer
**************** ** ****  .  *  *

37. spacer 1.14|29314|34|NZ_CP022263|CRISPRCasFinder matches to MK937591 (Microbacterium phage Cinna, complete genome) position: , mismatch: 10, identity: 0.706

ctcgccgagcgcggcagccagatcagtggcgggg	CRISPR spacer
ctcgccgagcgcggcatcccgatcctctccctgc	Protospacer
**************** ** ****  .  *  *

38. spacer 1.13|29257|34|NZ_CP022263|CRISPRCasFinder matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.676

acgctgggccagaaggtgatcgtgtccggcggac	CRISPR spacer
aaagcgggccagatggtggtcgtgtccggacagt	Protospacer
* . .******** ****.**********  ...

39. spacer 1.14|29314|34|NZ_CP022263|CRISPRCasFinder matches to NZ_AP012556 (Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence) position: , mismatch: 11, identity: 0.676

ctcgccgagcgcggcagccagatcagtggcgggg	CRISPR spacer
gccgccgagcgcagcagcccgatcagcccgtaga	Protospacer
 .**********.****** ******.    .*.

40. spacer 1.14|29314|34|NZ_CP022263|CRISPRCasFinder matches to NC_016588 (Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence) position: , mismatch: 11, identity: 0.676

ctcgccgagcgcggcagccagatcagtggcgggg	CRISPR spacer
ctcggcgagcgcggcggccagatcctcctccatc	Protospacer
**** **********.********  .  * .

41. spacer 1.14|29314|34|NZ_CP022263|CRISPRCasFinder matches to NZ_CP023152 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence) position: , mismatch: 11, identity: 0.676

ctcgccgagcgcggcagccagatcagtggcgggg	CRISPR spacer
gccgccgagcgcagcagcccgatcagcccgtaga	Protospacer
 .**********.****** ******.    .*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

83641 : 149825

Burkholderia_virus(20.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089113428.1\|83641_87364_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_089111284.1\|87748_88147_+	host attachment protein	NA	NA	NA	NA
WP_089111285.1\|88167_88497_+	thioredoxin family protein	NA	NA	NA	NA
WP_007962295.1\|89029_90520_+	glycine betaine/L-proline transporter ProP	Q6JIH2	Burkholderia_virus	1.4e-53	31.4
WP_089111287.1\|90853_91327_-	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_089111288.1\|91497_92280_+	EcsC family protein	NA	NA	NA	NA
WP_089111289.1\|92457_93114_+	DUF938 domain-containing protein	NA	NA	NA	NA
WP_089111290.1\|93364_95146_-	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_167382220.1\|95303_97577_-	DUF4175 domain-containing protein	NA	NA	NA	NA
WP_089111291.1\|97573_98773_-	hypothetical protein	NA	NA	NA	NA
WP_007962713.1\|98816_99713_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_089111292.1\|99726_100719_-	MoxR family ATPase	NA	NA	NA	NA
WP_007962711.1\|100850_101669_-	DUF4159 domain-containing protein	NA	NA	NA	NA
WP_007962710.1\|101665_103000_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_003487942.1\|103014_104649_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_042674735.1\|104926_105118_-	hypothetical protein	NA	NA	NA	NA
WP_167382221.1\|105341_106970_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_089111293.1\|107332_107722_-	hypothetical protein	NA	NA	NA	NA
WP_057663260.1\|107970_108981_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	4.3e-49	37.8
WP_016849085.1\|109246_110449_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_167382222.1\|110605_112744_+	TonB-dependent receptor	A0A1B0VCF0	Salmonella_phage	1.3e-68	41.5
WP_089111295.1\|112950_113247_+	hypothetical protein	NA	NA	NA	NA
WP_089113431.1\|114335_115865_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_089111296.1\|116042_116438_+	DUF779 domain-containing protein	NA	NA	NA	NA
WP_089111250.1\|116609_117590_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_022557861.1\|117705_117885_-	hypothetical protein	NA	NA	NA	NA
WP_080720923.1\|118126_118435_+	hypothetical protein	NA	NA	NA	NA
WP_007964742.1\|118434_119394_+	Ku protein	NA	NA	NA	NA
WP_089111297.1\|119530_120697_-	FMN-dependent L-lactate dehydrogenase LldD	NA	NA	NA	NA
WP_089111298.1\|120945_122181_+	serine hydrolase	NA	NA	NA	NA
WP_042675313.1\|122266_123466_+	sensor histidine kinase	NA	NA	NA	NA
WP_003489973.1\|123462_124095_+	response regulator transcription factor	NA	NA	NA	NA
WP_057663290.1\|124701_125100_+	hypothetical protein	NA	NA	NA	NA
WP_033481586.1\|125388_125937_+	hypothetical protein	NA	NA	NA	NA
WP_057663293.1\|126075_126474_-	hypothetical protein	NA	NA	NA	NA
WP_089111299.1\|126470_129818_-	AAA family ATPase	NA	NA	NA	NA
WP_089111300.1\|130099_131308_+	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_089111301.1\|131878_132901_-	sugar kinase	NA	NA	NA	NA
WP_007964720.1\|133186_135967_+	TonB-dependent receptor	NA	NA	NA	NA
WP_089111302.1\|136332_140199_+	hypothetical protein	NA	NA	NA	NA
WP_167382223.1\|140386_140596_+	hypothetical protein	NA	NA	NA	NA
WP_089111303.1\|140732_141989_+	SIR2 family protein	NA	NA	NA	NA
WP_089111304.1\|142075_143056_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089111305.1\|144562_144772_+	KTSC domain-containing protein	A0A0K1LMB5	Caulobacter_phage	4.0e-10	50.7
WP_089111250.1\|145022_146003_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089111250.1\|146260_147241_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_157768033.1\|147379_148219_+	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_089113432.1\|148312_148705_-	hypothetical protein	NA	NA	NA	NA
WP_089111307.1\|148737_149825_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8

DBSCAN-SWA_2

562638 : 592139

Xanthomonas_virus(33.33%)

tail,terminase,protease,portal,integrase,transposase

attL 581317:581332|attR 598501:598516

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089111462.1\|562638_564573_+\|terminase	phage terminase large subunit family protein	B7SYD3	Stenotrophomonas_phage	0.0e+00	81.7
WP_139369143.1\|564961_565549_+	hypothetical protein	NA	NA	NA	NA
WP_089111250.1\|565722_566703_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_039586149.1\|566845_567061_+	hypothetical protein	NA	NA	NA	NA
WP_078568068.1\|567060_568617_+\|portal	phage portal protein	A5LH29	Enterobacteria_phage	4.5e-82	39.8
WP_078568067.1\|568619_570827_+\|protease	Clp protease ClpP	A0A1B0YZU0	Pseudomonas_phage	4.7e-101	36.4
WP_078568066.1\|570884_571241_+	DUF2190 family protein	NA	NA	NA	NA
WP_078568065.1\|571323_571752_+	structural protein P5	B7SYD9	Stenotrophomonas_phage	1.1e-43	67.4
WP_039586140.1\|571751_572213_+	hypothetical protein	NA	NA	NA	NA
WP_089111463.1\|572209_572488_+	hypothetical protein	NA	NA	NA	NA
WP_078568063.1\|572484_572985_+	hypothetical protein	K7ZMJ4	Xanthomonas_citri_phage	5.6e-10	31.5
WP_078568062.1\|572984_573293_+	hypothetical protein	NA	NA	NA	NA
WP_078568061.1\|573289_574120_+	hypothetical protein	NA	NA	NA	NA
WP_078568060.1\|574116_574440_+	hypothetical protein	NA	NA	NA	NA
WP_078568059.1\|574432_574867_+	hypothetical protein	NA	NA	NA	NA
WP_078568058.1\|574897_575653_+	hypothetical protein	NA	NA	NA	NA
WP_078568057.1\|575652_576126_+	hypothetical protein	NA	NA	NA	NA
WP_167382237.1\|576122_576287_+	hypothetical protein	NA	NA	NA	NA
WP_089111464.1\|576287_578969_+\|tail	phage tail tape measure protein	C4ML16	Xanthomonas_virus	3.7e-100	33.8
WP_078568055.1\|578968_579325_+	hypothetical protein	C4ML17	Xanthomonas_virus	4.7e-19	41.5
WP_078568054.1\|579321_579789_+	DUF1833 family protein	Q52PL0	Xanthomonas_phage	8.3e-32	42.6
WP_078568053.1\|579788_580184_+	C40 family peptidase	Q7Y5J6	Xanthomonas_virus	6.3e-33	50.8
WP_078568052.1\|580171_584590_+	hypothetical protein	C4ML20	Xanthomonas_virus	0.0e+00	50.8
581317:581332	attL	NA	NA	NA	NA
WP_078568051.1\|584586_584898_+	hypothetical protein	NA	NA	NA	NA
WP_078568050.1\|584899_585577_+	hypothetical protein	NA	NA	NA	NA
WP_089111465.1\|585578_586232_+	hypothetical protein	NA	NA	NA	NA
WP_078568049.1\|586376_587171_+	DNA adenine methylase	B7SYF3	Stenotrophomonas_phage	2.1e-123	77.6
WP_139369142.1\|587276_588182_+	sel1 repeat family protein	NA	NA	NA	NA
WP_078568085.1\|589261_589468_-	hypothetical protein	NA	NA	NA	NA
WP_078568047.1\|589528_589753_+	hypothetical protein	NA	NA	NA	NA
WP_078568046.1\|589762_590701_+	hypothetical protein	NA	NA	NA	NA
WP_157768043.1\|591080_592139_-\|integrase	tyrosine-type recombinase/integrase	A0A2D1GMX8	Marinobacter_phage	5.8e-65	42.0
598501:598516	attR	NA	NA	NA	NA

DBSCAN-SWA_3

726327 : 793797

Moraxella_phage(14.29%)

tRNA,integrase,transposase

attL 732611:732670|attR 769089:770253

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057658666.1\|726327_727392_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.3e-101	57.7
WP_003484603.1\|727469_727826_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_089111510.1\|728053_730225_+	beta-glucosidase	NA	NA	NA	NA
WP_007966555.1\|730395_731574_-	PQQ-dependent sugar dehydrogenase	NA	NA	NA	NA
WP_057658662.1\|731756_732191_+	hypothetical protein	NA	NA	NA	NA
WP_007966558.1\|732245_732578_-	hypothetical protein	NA	NA	NA	NA
732611:732670	attL	NA	NA	NA	NA
WP_089111250.1\|732728_733709_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089111511.1\|733916_734414_-	hypothetical protein	NA	NA	NA	NA
WP_007966561.1\|734610_735927_-	amino acid permease	NA	NA	NA	NA
WP_057658656.1\|735923_736700_-	hypothetical protein	NA	NA	NA	NA
WP_089111512.1\|736955_738053_-	dipeptide epimerase	NA	NA	NA	NA
WP_089111513.1\|738049_739462_-	NlpC-P60 family protein	NA	NA	NA	NA
WP_089111514.1\|739834_740641_+	N-acetylmuramoyl-L-alanine amidase	A0A223VZK2	Agrobacterium_phage	8.5e-08	29.2
WP_089111515.1\|740731_741478_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_022560162.1\|741762_741960_+	CPXCG motif-containing cysteine-rich protein	NA	NA	NA	NA
WP_089111516.1\|742182_742560_+	hypothetical protein	NA	NA	NA	NA
WP_005923024.1\|742786_743140_+	hypothetical protein	NA	NA	NA	NA
WP_089111518.1\|743381_743780_+	hypothetical protein	NA	NA	NA	NA
WP_089096218.1\|743817_744570_+	HAD family hydrolase	NA	NA	NA	NA
WP_089111519.1\|744872_745445_+	hypothetical protein	NA	NA	NA	NA
WP_162808454.1\|745740_746358_+	hypothetical protein	NA	NA	NA	NA
WP_089111520.1\|746522_747890_+	VOC family protein	NA	NA	NA	NA
WP_081027436.1\|748363_748792_-	VOC family protein	NA	NA	NA	NA
WP_089111521.1\|749322_752463_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_007966591.1\|752596_755845_-	MMPL family transporter	NA	NA	NA	NA
WP_022560152.1\|755938_757183_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_089111522.1\|757441_758749_+	amidohydrolase	NA	NA	NA	NA
WP_007971305.1\|758913_759729_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	A0A2I7SAX1	Vibrio_phage	5.9e-33	34.0
WP_042805478.1\|759831_760125_+	LysM peptidoglycan-binding domain-containing protein	A0A0K2SUI2	Clostridium_phage	8.3e-06	46.8
WP_089111523.1\|760228_760786_+	hypothetical protein	NA	NA	NA	NA
WP_089111524.1\|761143_763375_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_022560147.1\|763448_763703_-	hypothetical protein	NA	NA	NA	NA
WP_089111525.1\|764531_766472_+\|integrase	integrase	NA	NA	NA	NA
WP_157768047.1\|766496_767672_-	hypothetical protein	NA	NA	NA	NA
WP_089111250.1\|768049_769030_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089111526.1\|775478_776216_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
769089:770253	attR	NA	NA	NA	NA
WP_089111527.1\|776928_779691_+	RHS repeat protein	NA	NA	NA	NA
WP_089111528.1\|784413_784824_+	hypothetical protein	NA	NA	NA	NA
WP_089113465.1\|784982_785339_-	hypothetical protein	NA	NA	NA	NA
WP_089111529.1\|785356_785671_-	hypothetical protein	NA	NA	NA	NA
WP_089111307.1\|786291_787378_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_089111530.1\|787783_788125_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015471702.1\|788320_788614_+	hypothetical protein	A0A141GEX6	Brucella_phage	2.0e-15	44.8
WP_078585920.1\|788644_788947_+	putative addiction module antidote protein	NA	NA	NA	NA
WP_015471705.1\|789145_790024_-	WYL domain-containing protein	NA	NA	NA	NA
WP_089111531.1\|791223_792367_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-89	58.8
WP_089111532.1\|792336_792765_+	hypothetical protein	NA	NA	NA	NA
WP_089111304.1\|792816_793797_+\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1088647 : 1096670

Enterobacteria_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005913448.1\|1088647_1089703_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.4e-82	47.1
WP_005913450.1\|1089754_1090642_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	8.5e-94	57.5
WP_016851441.1\|1090638_1091196_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	6.6e-44	48.9
WP_007962671.1\|1091192_1092092_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	4.1e-27	36.2
WP_089111666.1\|1092432_1093599_+	nucleotide sugar dehydrogenase	M1HZB2	Paramecium_bursaria_Chlorella_virus	1.5e-117	58.4
WP_007962673.1\|1093873_1095277_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	4.2e-47	29.8
WP_089111667.1\|1095323_1096670_-	phosphomannomutase	A0A127AWJ1	Bacillus_phage	2.0e-33	27.3

DBSCAN-SWA_5

1230360 : 1262846

Pseudomonas_phage(56.0%)

integrase,transposase

attL 1226437:1226451|attR 1266096:1266110

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1226437:1226451	attL	NA	NA	NA	NA
WP_089111725.1\|1230360_1231155_-	DNA adenine methylase	B7SYF3	Stenotrophomonas_phage	7.5e-126	79.5
WP_157768059.1\|1231303_1231774_-	hypothetical protein	V5Q7X8	Xylella_phage	3.3e-20	44.1
WP_089111727.1\|1231777_1232731_-	hypothetical protein	A0A2D2W237	Stenotrophomonas_phage	1.0e-108	60.1
WP_157768061.1\|1232741_1232912_-	hypothetical protein	NA	NA	NA	NA
WP_089111729.1\|1233747_1236231_-	hypothetical protein	J9RWA5	Pseudomonas_phage	1.5e-143	41.4
WP_089111730.1\|1236230_1237058_-	DUF2163 domain-containing protein	Q6UYJ5	Burkholderia_phage	1.9e-42	34.8
WP_089111731.1\|1237054_1238593_-	hypothetical protein	L7P813	Pseudomonas_phage	3.4e-130	49.2
WP_157768063.1\|1238754_1239693_-	hypothetical protein	NA	NA	NA	NA
WP_089111733.1\|1239662_1240562_-	hypothetical protein	A0A2D1GMZ0	Marinobacter_phage	2.0e-34	33.1
WP_157768065.1\|1242291_1243521_-	hypothetical protein	A0A2H4J7J3	uncultured_Caudovirales_phage	7.5e-48	44.8
WP_157768067.1\|1243932_1244073_-	hypothetical protein	NA	NA	NA	NA
WP_157768070.1\|1244114_1244543_-	hypothetical protein	Q5ZQX1	Pseudomonas_phage	1.2e-13	39.2
WP_089111737.1\|1244626_1245385_-	hypothetical protein	J9SVZ4	Pseudomonas_phage	4.4e-22	33.1
WP_089111738.1\|1245386_1245635_-	hypothetical protein	NA	NA	NA	NA
WP_089111739.1\|1245631_1246102_-	hypothetical protein	A0A0S4L2X9	Pseudomonas_phage	1.2e-30	45.0
WP_089111740.1\|1246098_1246629_-	DUF1320 domain-containing protein	Q5ZQX5	Pseudomonas_phage	2.6e-34	46.5
WP_157768072.1\|1246700_1247159_-	hypothetical protein	NA	NA	NA	NA
WP_089111742.1\|1247228_1248176_-	hypothetical protein	R9U4B8	Rhizobium_phage	1.6e-66	42.6
WP_167382250.1\|1248251_1248599_-	DUF2190 domain-containing protein	NA	NA	NA	NA
WP_089111743.1\|1248631_1249780_-	peptidase	A0A0S4L0J5	Pseudomonas_phage	1.9e-77	51.4
WP_089111744.1\|1249994_1250570_-	phage virion morphogenesis protein	J9SU29	Pseudomonas_phage	1.8e-28	44.9
WP_089111745.1\|1250569_1251844_-	hypothetical protein	J9STS2	Pseudomonas_phage	3.9e-84	62.4
WP_089111746.1\|1251847_1253377_-	DUF935 family protein	Q5ZQY4	Pseudomonas_phage	7.6e-167	59.2
WP_089111747.1\|1253373_1255095_-	hypothetical protein	A0A219VH72	Ochrobactrum_phage	1.6e-101	43.3
WP_089111748.1\|1255094_1255646_-	DUF3486 family protein	Q6QIC2	Burkholderia_phage	9.8e-32	47.2
WP_089113477.1\|1255650_1255947_-	hypothetical protein	A0A0S4L0A3	Pseudomonas_phage	1.2e-31	62.2
WP_089111749.1\|1255954_1256269_-	hypothetical protein	A0A0S4L2V7	Pseudomonas_phage	9.9e-13	37.2
WP_157768074.1\|1256265_1256619_-	hypothetical protein	NA	NA	NA	NA
WP_089111750.1\|1256548_1256968_-	hypothetical protein	NA	NA	NA	NA
WP_157768076.1\|1256964_1257690_-	hypothetical protein	J9Q7Y7	Salmonella_phage	3.5e-37	48.2
WP_089113478.1\|1257879_1258104_+	hypothetical protein	A0A2C9CY14	Yersinia_phage	4.4e-15	56.8
WP_089111752.1\|1258104_1258494_-	hypothetical protein	NA	NA	NA	NA
WP_089111753.1\|1258490_1258946_-	hypothetical protein	NA	NA	NA	NA
WP_089111754.1\|1259047_1259257_+	hypothetical protein	NA	NA	NA	NA
WP_089111755.1\|1259253_1259490_+	hypothetical protein	NA	NA	NA	NA
WP_157768078.1\|1259468_1259801_+	hypothetical protein	NA	NA	NA	NA
WP_089111757.1\|1259797_1260103_+	hypothetical protein	NA	NA	NA	NA
WP_089111758.1\|1260117_1261038_+	hypothetical protein	Q5ZR03	Pseudomonas_phage	2.0e-21	30.3
WP_089111759.1\|1261040_1262846_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0S4L2U5	Pseudomonas_phage	2.3e-109	42.0
1266096:1266110	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1506756 : 1558967

Shigella_phage(33.33%)

tRNA,integrase,transposase

attL 1510930:1510947|attR 1543569:1543586

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007964566.1\|1506756_1507515_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_007964565.1\|1507737_1508532_-	thiazole synthase	NA	NA	NA	NA
WP_022558627.1\|1508581_1508782_-	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_088411727.1\|1508970_1510755_+	autotransporter domain-containing protein	NA	NA	NA	NA
1510930:1510947	attL	NA	NA	NA	NA
WP_089111848.1\|1511014_1512577_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_157768085.1\|1512818_1513445_+	hypothetical protein	NA	NA	NA	NA
WP_089113486.1\|1513878_1514238_-	hypothetical protein	NA	NA	NA	NA
WP_089111849.1\|1514255_1514570_-	hypothetical protein	NA	NA	NA	NA
WP_089111850.1\|1514626_1515388_-	hypothetical protein	NA	NA	NA	NA
WP_167382252.1\|1515496_1515850_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_089095842.1\|1515952_1516717_-	abortive infection family protein	NA	NA	NA	NA
WP_089113487.1\|1516849_1522453_+	DUF3320 domain-containing protein	NA	NA	NA	NA
WP_167382253.1\|1524315_1525158_-	hypothetical protein	NA	NA	NA	NA
WP_089111851.1\|1525318_1526299_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_167382359.1\|1527291_1527798_+	hypothetical protein	NA	NA	NA	NA
WP_089111853.1\|1527838_1528333_+	hypothetical protein	NA	NA	NA	NA
WP_089111854.1\|1528621_1528846_+	hypothetical protein	NA	NA	NA	NA
WP_089111855.1\|1529240_1529720_+	DNA repair protein RadC	NA	NA	NA	NA
WP_089111856.1\|1529796_1529988_+	hypothetical protein	NA	NA	NA	NA
WP_157768087.1\|1530501_1530777_+	hypothetical protein	NA	NA	NA	NA
WP_089111858.1\|1530769_1532179_+	hypothetical protein	NA	NA	NA	NA
WP_089111307.1\|1532757_1533844_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_089111859.1\|1534678_1535695_-	hypothetical protein	NA	NA	NA	NA
WP_089111860.1\|1535822_1536755_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089111531.1\|1536806_1537950_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-89	58.8
WP_089111861.1\|1538091_1538331_-	hypothetical protein	NA	NA	NA	NA
WP_089111862.1\|1538646_1539105_-	DNA mismatch endonuclease Vsr	E5E3X5	Burkholderia_phage	4.6e-43	64.5
WP_089111863.1\|1539332_1539653_-	hypothetical protein	NA	NA	NA	NA
WP_089111864.1\|1539833_1540160_-	hypothetical protein	NA	NA	NA	NA
WP_089111865.1\|1540426_1542022_+	MobA/MobL family protein	NA	NA	NA	NA
WP_089111866.1\|1542095_1542488_-	transcriptional regulator	NA	NA	NA	NA
WP_011348355.1\|1542471_1542753_-	hypothetical protein	NA	NA	NA	NA
WP_089111867.1\|1542818_1543160_-	hypothetical protein	NA	NA	NA	NA
WP_089111868.1\|1544166_1544826_+	thermonuclease family protein	NA	NA	NA	NA
1543569:1543586	attR	NA	NA	NA	NA
WP_007962003.1\|1544935_1545328_+	hypothetical protein	NA	NA	NA	NA
WP_003490669.1\|1545418_1545811_+	H-NS histone family protein	NA	NA	NA	NA
WP_089111869.1\|1546445_1548578_-	glycogen debranching protein GlgX	NA	NA	NA	NA
WP_167382254.1\|1549042_1549960_+	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	2.4e-30	32.0
WP_007962331.1\|1550146_1550623_+	hypothetical protein	NA	NA	NA	NA
WP_003490678.1\|1550648_1551326_+	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	7.4e-05	27.4
WP_162808441.1\|1551318_1552653_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_089111870.1\|1552755_1553151_-	type I toxin-antitoxin system SymE family toxin	NA	NA	NA	NA
WP_089111872.1\|1553641_1553854_-	hypothetical protein	NA	NA	NA	NA
WP_089111531.1\|1557822_1558967_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-89	58.8

DBSCAN-SWA_7

2278242 : 2325545

Xanthomonas_virus(17.39%)

tail,terminase,head,capsid,transposase,integrase,portal

attL 2278990:2279049|attR 2329930:2329989

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007965965.1\|2278242_2278779_-	lipocalin family protein	A0A2I2L3Z7	Orpheovirus	9.0e-14	33.1
2278990:2279049	attL	NA	NA	NA	NA
WP_157768097.1\|2279101_2279971_-\|integrase	tyrosine-type recombinase/integrase	A4PE72	Ralstonia_virus	8.4e-54	43.9
WP_157768223.1\|2280003_2280330_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_089112159.1\|2280349_2280796_-	hypothetical protein	NA	NA	NA	NA
WP_089112160.1\|2280792_2281323_-	hypothetical protein	NA	NA	NA	NA
WP_089112161.1\|2281326_2282235_-	recombination-associated protein RdgC	S4TWL4	Salmonella_phage	6.3e-44	34.2
WP_089112162.1\|2282256_2283018_-	hypothetical protein	A0A2H4IY33	uncultured_phage	4.3e-54	44.0
WP_089112163.1\|2283010_2283553_-	hypothetical protein	NA	NA	NA	NA
WP_089112164.1\|2283545_2283848_-	hypothetical protein	NA	NA	NA	NA
WP_089112165.1\|2283819_2284671_-	DNA adenine methylase	A0A0K1LM14	Caulobacter_phage	4.5e-76	52.0
WP_089112166.1\|2284667_2286644_-	DNA methyltransferase	Q5QF27	Pseudomonas_virus	1.7e-150	46.9
WP_089112167.1\|2286701_2287187_-	hypothetical protein	NA	NA	NA	NA
WP_089112168.1\|2287183_2287441_-	hypothetical protein	NA	NA	NA	NA
WP_089113507.1\|2287449_2287761_-	hypothetical protein	NA	NA	NA	NA
WP_089112169.1\|2287757_2288012_-	hypothetical protein	NA	NA	NA	NA
WP_089112170.1\|2288126_2288444_-	hypothetical protein	NA	NA	NA	NA
WP_089112171.1\|2288445_2288739_-	hypothetical protein	NA	NA	NA	NA
WP_089112172.1\|2288735_2289074_-	hypothetical protein	NA	NA	NA	NA
WP_089112173.1\|2289070_2289313_-	hypothetical protein	NA	NA	NA	NA
WP_089112174.1\|2289360_2289771_-	DUF1566 domain-containing protein	NA	NA	NA	NA
WP_089112175.1\|2290383_2291181_-	helix-turn-helix transcriptional regulator	C8CLH0	Xylella_phage	1.6e-35	45.3
WP_157768099.1\|2291211_2291451_+	hypothetical protein	NA	NA	NA	NA
WP_157768101.1\|2291624_2291786_+	hypothetical protein	NA	NA	NA	NA
WP_089112176.1\|2291782_2291965_-	hypothetical protein	NA	NA	NA	NA
WP_089112177.1\|2292261_2292498_-	hypothetical protein	NA	NA	NA	NA
WP_089112178.1\|2292945_2293170_-	hypothetical protein	NA	NA	NA	NA
WP_157768103.1\|2293316_2293496_-	hypothetical protein	NA	NA	NA	NA
WP_089112180.1\|2293531_2294113_+	hypothetical protein	NA	NA	NA	NA
WP_089112181.1\|2294105_2294495_+	hypothetical protein	NA	NA	NA	NA
WP_089112182.1\|2294495_2296907_+	toprim domain-containing protein	B7SYD0	Stenotrophomonas_phage	0.0e+00	77.1
WP_157768105.1\|2297110_2297248_+	hypothetical protein	NA	NA	NA	NA
WP_089112183.1\|2297244_2297826_+	hypothetical protein	B7SYD2	Stenotrophomonas_phage	1.7e-50	54.0
WP_089112185.1\|2298019_2298205_+	hypothetical protein	NA	NA	NA	NA
WP_089113508.1\|2298201_2300136_+\|terminase	phage terminase large subunit family protein	B7SYD3	Stenotrophomonas_phage	0.0e+00	83.4
WP_089112186.1\|2300136_2300508_+	hypothetical protein	NA	NA	NA	NA
WP_089112187.1\|2300630_2301200_+	lipoprotein	NA	NA	NA	NA
WP_089112188.1\|2301199_2301646_+	hypothetical protein	NA	NA	NA	NA
WP_089112189.1\|2301929_2302328_+	hypothetical protein	NA	NA	NA	NA
WP_089112190.1\|2302324_2303290_+	hypothetical protein	A0A0B5A507	Paenibacillus_phage	8.0e-29	54.6
WP_157768107.1\|2303362_2304277_-	hypothetical protein	NA	NA	NA	NA
WP_089112192.1\|2304643_2304859_+	hypothetical protein	NA	NA	NA	NA
WP_089112193.1\|2304858_2306484_+\|portal	phage portal protein	A0A067ZJA4	Vibrio_phage	6.3e-95	42.9
WP_089112194.1\|2306480_2307779_+	S49 family peptidase	A0A219YB02	Aeromonas_phage	9.3e-65	48.9
WP_089112195.1\|2307792_2308158_+\|head	head decoration protein	NA	NA	NA	NA
WP_089112196.1\|2308191_2309217_+\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	6.4e-61	42.1
WP_089112197.1\|2309287_2309800_+	glycoside hydrolase family 108 protein	A0A0M3LSH2	Mannheimia_phage	1.1e-45	57.4
WP_089112198.1\|2309799_2310264_+	hypothetical protein	NA	NA	NA	NA
WP_089112199.1\|2310260_2310545_+	hypothetical protein	NA	NA	NA	NA
WP_089113509.1\|2310541_2311042_+	hypothetical protein	K7ZMJ4	Xanthomonas_citri_phage	2.0e-07	29.1
WP_089112200.1\|2311041_2311350_+	hypothetical protein	NA	NA	NA	NA
WP_089112201.1\|2311346_2312207_+	hypothetical protein	A0A291AUL1	Sinorhizobium_phage	4.0e-16	26.8
WP_089112202.1\|2312203_2312524_+	hypothetical protein	NA	NA	NA	NA
WP_089112203.1\|2312516_2312951_+	hypothetical protein	NA	NA	NA	NA
WP_089112204.1\|2312990_2313734_+	hypothetical protein	NA	NA	NA	NA
WP_089112205.1\|2313730_2314210_+	hypothetical protein	NA	NA	NA	NA
WP_089112206.1\|2314371_2317065_+\|tail	phage tail tape measure protein	C4ML16	Xanthomonas_virus	2.2e-100	32.4
WP_089112207.1\|2317064_2317421_+	hypothetical protein	C4ML17	Xanthomonas_virus	3.6e-19	41.5
WP_089112208.1\|2317417_2317885_+	DUF1833 family protein	Q52PL0	Xanthomonas_phage	1.6e-30	42.6
WP_089112209.1\|2317884_2318277_+	C40 family peptidase	Q2NPH1	Xanthomonas_virus	7.0e-32	53.6
WP_089112210.1\|2318267_2322689_+	hypothetical protein	C4ML20	Xanthomonas_virus	0.0e+00	49.1
WP_078568051.1\|2322685_2322997_+	hypothetical protein	NA	NA	NA	NA
WP_089112211.1\|2322998_2323676_+	hypothetical protein	NA	NA	NA	NA
WP_089112212.1\|2323678_2324320_+	hypothetical protein	NA	NA	NA	NA
WP_089112213.1\|2324400_2325545_-\|transposase	IS3-like element ISXac3 family transposase	U5P429	Shigella_phage	2.1e-89	59.2
2329930:2329989	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2794262 : 2814118

Xanthomonas_phage(61.11%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089112387.1\|2794262_2795324_+	replication protein	S0F3F7	Stenotrophomonas_phage	6.9e-66	41.0
WP_089112388.1\|2795428_2795728_+	single-stranded DNA-binding protein	S0F3B2	Stenotrophomonas_phage	2.1e-20	51.0
WP_089112389.1\|2795742_2795937_+	hypothetical protein	NA	NA	NA	NA
WP_089112390.1\|2795941_2796184_+	hypothetical protein	NA	NA	NA	NA
WP_089112391.1\|2796335_2797733_+	hypothetical protein	A0A1W6DXV5	Xanthomonas_phage	3.0e-109	65.3
WP_089112392.1\|2797734_2798031_+	hypothetical protein	NA	NA	NA	NA
WP_089112393.1\|2798030_2799242_+	zonular occludens toxin	A0A077JGB2	Xanthomonas_phage	8.7e-73	39.0
WP_167382289.1\|2799651_2800005_-	hypothetical protein	NA	NA	NA	NA
WP_089113532.1\|2800613_2800886_+	hypothetical protein	A0A1W6DXK4	Xanthomonas_phage	4.4e-17	86.0
WP_089112394.1\|2800882_2801065_+	hypothetical protein	NA	NA	NA	NA
WP_089112395.1\|2801057_2802164_+	replication protein	S0F3I3	Stenotrophomonas_phage	7.7e-161	75.4
WP_089112396.1\|2802160_2802457_+	single-stranded DNA-binding protein	B1NI78	Stenotrophomonas_phage	3.5e-28	68.4
WP_089113533.1\|2802481_2802709_+	hypothetical protein	NA	NA	NA	NA
WP_089112397.1\|2802731_2802989_+	hypothetical protein	NA	NA	NA	NA
WP_157768129.1\|2803116_2804508_+	hypothetical protein	A0A1W6DXV5	Xanthomonas_phage	4.1e-103	57.6
WP_157768131.1\|2804507_2804828_+	DUF2523 domain-containing protein	NA	NA	NA	NA
WP_089112399.1\|2804824_2806003_+	zonular occludens toxin family protein	B1NI81	Stenotrophomonas_phage	1.1e-72	43.0
WP_089113534.1\|2806061_2806400_-	hypothetical protein	Q38057	Xanthomonas_phage	1.3e-50	83.9
WP_089112400.1\|2806581_2806947_+	hypothetical protein	A0A077JDD0	Xanthomonas_phage	6.7e-21	51.3
WP_089113535.1\|2807117_2807414_-	hypothetical protein	A0A1W6DXU7	Xanthomonas_phage	3.5e-12	43.8
WP_089112399.1\|2807612_2808791_-	zonular occludens toxin family protein	B1NI81	Stenotrophomonas_phage	1.1e-72	43.0
WP_157768131.1\|2808787_2809108_-	DUF2523 domain-containing protein	NA	NA	NA	NA
WP_157768133.1\|2809107_2810502_-	hypothetical protein	A0A1D6ZIU5	Xanthomonas_phage	6.2e-99	55.2
WP_089112397.1\|2810632_2810890_-	hypothetical protein	NA	NA	NA	NA
WP_089113533.1\|2810912_2811140_-	hypothetical protein	NA	NA	NA	NA
WP_089112401.1\|2811164_2811458_-	DNA-binding protein	A0A1W6DXU2	Xanthomonas_phage	3.5e-12	44.6
WP_089113536.1\|2811454_2812429_-	replication initiation protein	A0A1W6DXW7	Xanthomonas_phage	6.0e-117	61.6
WP_089112402.1\|2812557_2812746_-	hypothetical protein	A0A077JGB8	Xanthomonas_phage	2.3e-17	78.7
WP_022559200.1\|2813314_2814118_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.0e-09	25.6

DBSCAN-SWA_9

2823501 : 2899523

Escherichia_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089111531.1\|2823501_2824646_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-89	58.8
WP_089112408.1\|2824672_2825008_+	hypothetical protein	NA	NA	NA	NA
WP_089112409.1\|2825784_2826330_-	hypothetical protein	NA	NA	NA	NA
WP_009602864.1\|2826379_2826775_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_002804328.1\|2826771_2827023_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_046932484.1\|2827204_2827771_+	recombinase family protein	Q71TD8	Escherichia_phage	1.8e-44	53.6
WP_089111307.1\|2827935_2829022_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_089112410.1\|2829198_2829861_+	recombinase family protein	NA	NA	NA	NA
WP_089112411.1\|2830036_2831308_-	type III effector	NA	NA	NA	NA
WP_089112413.1\|2832106_2832808_-	NYN domain-containing protein	NA	NA	NA	NA
WP_089112414.1\|2833257_2836218_-\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_089112415.1\|2837387_2838455_+	DNA-binding protein	NA	NA	NA	NA
WP_089112416.1\|2838442_2839480_-	hypothetical protein	NA	NA	NA	NA
WP_089112417.1\|2839902_2841225_-	pectate lyase	NA	NA	NA	NA
WP_089112418.1\|2842665_2844492_-	transmembrane repetitive protein	NA	NA	NA	NA
WP_007964449.1\|2844505_2845105_-	NfuA family Fe-S biogenesis protein	NA	NA	NA	NA
WP_003489213.1\|2845193_2845550_+	4a-hydroxytetrahydrobiopterin dehydratase	NA	NA	NA	NA
WP_042675236.1\|2845546_2845969_+	energy transducer TonB	NA	NA	NA	NA
WP_007964444.1\|2846234_2847053_+	zinc transporter ZupT	NA	NA	NA	NA
WP_089112419.1\|2847346_2849158_+	DUF3300 domain-containing protein	NA	NA	NA	NA
WP_089112420.1\|2849190_2850177_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_089112421.1\|2850586_2854246_+	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_003489223.1\|2854771_2855419_-	response regulator	NA	NA	NA	NA
WP_007964432.1\|2855658_2856405_-	sulfurtransferase	NA	NA	NA	NA
WP_089112422.1\|2856506_2856872_-	hypothetical protein	NA	NA	NA	NA
WP_089112423.1\|2856931_2857363_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_089112424.1\|2857373_2858639_+	TIGR03862 family flavoprotein	NA	NA	NA	NA
WP_089095404.1\|2858622_2859915_-	nucleotide sugar dehydrogenase	NA	NA	NA	NA
WP_053054509.1\|2860907_2861183_-	DUF3577 domain-containing protein	NA	NA	NA	NA
WP_078584136.1\|2861845_2862292_+	autotransporter	NA	NA	NA	NA
WP_011037249.1\|2862438_2864145_+	tannase/feruloyl esterase family alpha/beta hydrolase	NA	NA	NA	NA
WP_167382290.1\|2864593_2871232_+	DUF3320 domain-containing protein	NA	NA	NA	NA
WP_167382291.1\|2871267_2872200_+	TIGR04141 family sporadically distributed protein	NA	NA	NA	NA
WP_167382365.1\|2872203_2872935_+	TIGR04141 family sporadically distributed protein	NA	NA	NA	NA
WP_089113538.1\|2874415_2875063_+	tyrosine protein phosphatase	NA	NA	NA	NA
WP_139369220.1\|2875526_2876372_+	avirulence protein	H6WZN3	Escherichia_phage	6.9e-61	50.6
WP_139369219.1\|2876433_2877744_+	avirulence protein	NA	NA	NA	NA
WP_167382292.1\|2877753_2878868_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.8e-41	37.1
WP_089113539.1\|2879825_2880038_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_089112428.1\|2880084_2880960_+	ParA family protein	NA	NA	NA	NA
WP_012438470.1\|2880943_2881204_+	hypothetical protein	NA	NA	NA	NA
WP_089112429.1\|2881196_2882840_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_089112430.1\|2882855_2883416_+	DUF2857 domain-containing protein	NA	NA	NA	NA
WP_089112431.1\|2883419_2884646_+	hypothetical protein	NA	NA	NA	NA
WP_011347489.1\|2884967_2885723_+	TIGR03761 family integrating conjugative element protein	NA	NA	NA	NA
WP_011269738.1\|2885719_2886253_+	DUF3158 family protein	NA	NA	NA	NA
WP_011347487.1\|2886326_2886767_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_089112432.1\|2887047_2889060_+	DNA topoisomerase III	A0A0G2Y787	Acanthamoeba_polyphaga_mimivirus	2.2e-12	23.3
WP_089112433.1\|2889594_2891133_+	DNA cytosine methyltransferase	A0A1B0V7P0	Salmonella_phage	7.8e-95	39.5
WP_089112434.1\|2891605_2891818_+	hypothetical protein	NA	NA	NA	NA
WP_011269733.1\|2891839_2892232_+	hypothetical protein	NA	NA	NA	NA
WP_089112435.1\|2892471_2894589_+	hypothetical protein	NA	NA	NA	NA
WP_042837148.1\|2894588_2895515_+	hypothetical protein	NA	NA	NA	NA
WP_052461948.1\|2895727_2895943_+	hypothetical protein	NA	NA	NA	NA
WP_040239412.1\|2896240_2897053_+	GTPase	NA	NA	NA	NA
WP_040239414.1\|2897476_2898427_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_089111250.1\|2898542_2899523_-\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_10

3363701 : 3436700

Pseudomonas_phage(28.57%)

tail,terminase,head,capsid,portal,integrase,transposase

attL 3358021:3358036|attR 3422420:3422435

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3358021:3358036	attL	NA	NA	NA	NA
WP_089111250.1\|3363701_3364682_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_007963329.1\|3364835_3365270_+	hypothetical protein	NA	NA	NA	NA
WP_007963328.1\|3365253_3366753_-	sensor kinase	NA	NA	NA	NA
WP_033481945.1\|3367011_3368439_-	sugar porter family MFS transporter	NA	NA	NA	NA
WP_089112566.1\|3368524_3369862_-	xylose isomerase	NA	NA	NA	NA
WP_089112567.1\|3369909_3371403_-	xylulokinase	NA	NA	NA	NA
WP_089112568.1\|3371399_3373763_-	glycoside hydrolase family 95 protein	NA	NA	NA	NA
WP_089112569.1\|3373854_3376758_-	DUF5110 domain-containing protein	NA	NA	NA	NA
WP_167382309.1\|3376862_3378605_-	DUF5597 domain-containg protein	NA	NA	NA	NA
WP_089113558.1\|3378616_3380533_-	9-O-acetylesterase	NA	NA	NA	NA
WP_089112570.1\|3380639_3382895_-	cellulase	NA	NA	NA	NA
WP_089112571.1\|3383006_3385727_-	TonB-dependent receptor	NA	NA	NA	NA
WP_007966740.1\|3389254_3390226_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_057659798.1\|3390642_3391275_+	2-dehydro-3-deoxy-6-phosphogalactonate aldolase	NA	NA	NA	NA
WP_007966742.1\|3391271_3392420_+	galactonate dehydratase	Q6A202	Oenococcus_phage	4.2e-53	34.3
WP_007966743.1\|3392413_3393325_+	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_089095556.1\|3393321_3394200_+	2-dehydro-3-deoxygalactonokinase	NA	NA	NA	NA
WP_003481917.1\|3394283_3394607_+	ferredoxin family protein	NA	NA	NA	NA
WP_089095557.1\|3394738_3395257_-	hypothetical protein	NA	NA	NA	NA
WP_057659820.1\|3395273_3396182_-	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_033012116.1\|3396341_3396902_+	glycine cleavage system protein R	NA	NA	NA	NA
WP_003481909.1\|3396913_3397264_+	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_089112573.1\|3397301_3397784_+	peroxiredoxin	NA	NA	NA	NA
WP_007966750.1\|3397866_3399264_+	PhoH family protein	A0A2I7SAD7	Vibrio_phage	1.3e-72	37.8
WP_089112574.1\|3399263_3399746_+	hypothetical protein	NA	NA	NA	NA
WP_089112575.1\|3399752_3400424_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_162808386.1\|3400461_3401271_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_089112576.1\|3401267_3402149_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_089112577.1\|3402606_3403599_-	hypothetical protein	NA	NA	NA	NA
WP_089112578.1\|3403643_3404588_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_007966758.1\|3404722_3405424_+	pirin family protein	NA	NA	NA	NA
WP_089112579.1\|3405835_3407794_-	PAS domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	2.1e-12	42.0
WP_089112580.1\|3409077_3410232_+\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	6.1e-84	44.4
WP_089112581.1\|3410686_3411199_+	hypothetical protein	NA	NA	NA	NA
WP_089112583.1\|3411587_3412526_-	hypothetical protein	NA	NA	NA	NA
WP_089112584.1\|3412535_3412760_-	hypothetical protein	NA	NA	NA	NA
WP_089112585.1\|3412820_3413024_+	hypothetical protein	NA	NA	NA	NA
WP_157768145.1\|3413053_3413404_-	hypothetical protein	NA	NA	NA	NA
WP_089112586.1\|3413750_3414197_+	hypothetical protein	NA	NA	NA	NA
WP_089112587.1\|3414190_3414916_-	hypothetical protein	A0A2K9VHT7	Pseudomonas_phage	3.3e-11	31.4
WP_089112588.1\|3414916_3415216_-	hypothetical protein	NA	NA	NA	NA
WP_089112589.1\|3415215_3418680_-	DUF1983 domain-containing protein	A0A2R3UA88	Siphoviridae_environmental_samples	0.0e+00	59.6
WP_089112590.1\|3418676_3419270_-\|tail	tail assembly protein	Q3HQU4	Burkholderia_phage	7.5e-54	62.1
WP_078564783.1\|3419266_3420010_-	peptidase P60	A0A2R3UAR4	Siphoviridae_environmental_samples	5.0e-79	58.8
WP_089112591.1\|3420076_3420775_-\|tail	phage minor tail protein L	A0A2R3UA90	Siphoviridae_environmental_samples	4.6e-103	73.5
WP_157768149.1\|3420771_3421701_-	hypothetical protein	A0A2H4PH88	Klebsiella_phage	7.7e-21	37.3
WP_089113559.1\|3421710_3422043_-\|tail	phage tail protein	A0A2R3UA73	Siphoviridae_environmental_samples	2.0e-24	47.3
WP_089112593.1\|3422035_3424285_-	hypothetical protein	D4FUM0	Pseudomonas_phage	6.8e-55	37.0
3422420:3422435	attR	NA	NA	NA	NA
WP_127172361.1\|3424295_3424508_-	hypothetical protein	NA	NA	NA	NA
WP_089112595.1\|3424540_3424930_-	hypothetical protein	NA	NA	NA	NA
WP_046932034.1\|3424985_3425486_-	hypothetical protein	NA	NA	NA	NA
WP_057681487.1\|3425540_3425894_-	DUF3168 domain-containing protein	B5WZT0	Pseudomonas_phage	4.1e-07	33.1
WP_057681488.1\|3425893_3426385_-	hypothetical protein	NA	NA	NA	NA
WP_089112596.1\|3426387_3426750_-\|head	phage head closure protein	A0A1J0GUY4	Halomonas_phage	7.1e-23	58.6
WP_089112597.1\|3426749_3427145_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_089112598.1\|3427137_3428004_-	hypothetical protein	NA	NA	NA	NA
WP_089112599.1\|3427996_3429427_-\|portal	phage portal protein	B5WZS2	Pseudomonas_phage	4.2e-135	58.7
WP_089112600.1\|3429423_3429753_-	hypothetical protein	NA	NA	NA	NA
WP_089112601.1\|3429812_3431252_-\|capsid	phage major capsid protein	S4TNE3	Salmonella_phage	3.3e-103	44.6
WP_089112602.1\|3431316_3431889_-	peptidase U35	Q6H9U8	Enterobacteria_phage	2.2e-34	47.3
WP_089112603.1\|3431892_3433584_-\|terminase	terminase large subunit	A0A0U4B0M7	Pseudomonas_phage	1.0e-233	71.0
WP_057681493.1\|3433669_3434086_-\|terminase	P27 family phage terminase small subunit	NA	NA	NA	NA
WP_089112604.1\|3434096_3434528_-	HNH endonuclease	D4FUN2	Pseudomonas_phage	3.5e-16	47.1
WP_157768151.1\|3434527_3434764_-	hypothetical protein	NA	NA	NA	NA
WP_089112605.1\|3434760_3435234_-	hypothetical protein	NA	NA	NA	NA
WP_089112606.1\|3435268_3435547_-	hypothetical protein	NA	NA	NA	NA
WP_089112607.1\|3435543_3436047_-	hypothetical protein	Q2NPA5	Xanthomonas_phage	4.6e-20	40.0
WP_089112608.1\|3436043_3436700_-	glycoside hydrolase family 19 protein	A0A0X8WP64	Ralstonia_phage	2.2e-38	43.9

DBSCAN-SWA_11

3448300 : 3463577

Pseudomonas_virus(11.11%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089112620.1\|3448300_3450415_+	DNA methyltransferase	Q5QF27	Pseudomonas_virus	2.5e-144	42.4
WP_089112621.1\|3450411_3451677_+	site-specific DNA-methyltransferase	A0A2K9VGT2	Pontimonas_phage	1.4e-78	40.4
WP_089112622.1\|3451673_3451952_+	hypothetical protein	NA	NA	NA	NA
WP_089112623.1\|3451944_3452310_+	hypothetical protein	NA	NA	NA	NA
WP_089112624.1\|3452302_3453019_+	hypothetical protein	A0A2H4IY33	uncultured_phage	6.1e-50	42.6
WP_089112625.1\|3453040_3453949_+	recombination-associated protein RdgC	S4TWL4	Salmonella_phage	4.8e-44	34.2
WP_157768159.1\|3453952_3454924_+	hypothetical protein	NA	NA	NA	NA
WP_157768161.1\|3454920_3455085_+	hypothetical protein	NA	NA	NA	NA
WP_089113563.1\|3455415_3455634_+	hypothetical protein	NA	NA	NA	NA
WP_089112627.1\|3455620_3455845_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_089112628.1\|3456064_3456277_-	carbon storage regulator CsrA	J7I430	Pseudomonas_phage	1.5e-12	74.5
WP_089112629.1\|3456416_3459065_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.7e-84	40.0
WP_007966764.1\|3459166_3459655_-	recombination regulator RecX	NA	NA	NA	NA
WP_003481871.1\|3459967_3461002_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	5.1e-114	61.3
WP_007966767.1\|3461174_3461816_-	transcriptional repressor LexA	A0A1W6JNS2	Morganella_phage	2.4e-13	40.2
WP_007966769.1\|3461900_3463577_-	2-polyprenylphenol 6-hydroxylase	G8DDN0	Micromonas_pusilla_virus	1.9e-41	29.4

DBSCAN-SWA_12

3887662 : 4001444

Leptospira_phage(16.67%)

tRNA,integrase,transposase,protease

attL 3938254:3938270|attR 3991596:3991612

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089112787.1\|3887662_3890503_-\|protease	autotransporter serine protease	A0A1V0SBG2	Catovirus	3.9e-07	24.3
WP_089112788.1\|3890658_3891834_+	thiolase family protein	NA	NA	NA	NA
WP_089112789.1\|3891956_3892298_+	hypothetical protein	NA	NA	NA	NA
WP_022559764.1\|3892526_3892853_+	hypothetical protein	NA	NA	NA	NA
WP_007974385.1\|3892960_3894670_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	9.5e-17	37.5
WP_022559766.1\|3894908_3895466_+	polymer-forming cytoskeletal protein	NA	NA	NA	NA
WP_003489443.1\|3895462_3895828_+	hypothetical protein	NA	NA	NA	NA
WP_007967364.1\|3896066_3897089_+	ligase-associated DNA damage response exonuclease	NA	NA	NA	NA
WP_022559767.1\|3897085_3897319_+	hypothetical protein	NA	NA	NA	NA
WP_007974380.1\|3897315_3898920_+	ATP-dependent DNA ligase	A0A2H4JD86	uncultured_Caudovirales_phage	2.4e-09	29.0
WP_089112790.1\|3898916_3901418_+	ligase-associated DNA damage response DEXH box helicase	NA	NA	NA	NA
WP_078586552.1\|3901407_3902052_+	ligase-associated DNA damage response endonuclease PdeM	NA	NA	NA	NA
WP_089112791.1\|3902079_3903351_-	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_003488188.1\|3903446_3903653_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-20	70.1
WP_089112792.1\|3903740_3904493_-	S-methyl-5'-thioinosine phosphorylase	NA	NA	NA	NA
WP_003488192.1\|3904575_3905130_-	hypoxanthine-guanine phosphoribosyltransferase	NA	NA	NA	NA
WP_089112793.1\|3905129_3906134_-	beta-N-acetylhexosaminidase	NA	NA	NA	NA
WP_089112794.1\|3906251_3907829_-	cryptochrome/photolyase family protein	E3T4R9	Cafeteria_roenbergensis_virus	9.0e-46	28.0
WP_089112795.1\|3908009_3909044_-	NAD(P)-binding protein	NA	NA	NA	NA
WP_089113584.1\|3909060_3909744_-	DsbA family oxidoreductase	NA	NA	NA	NA
WP_089112796.1\|3909959_3910457_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_033481243.1\|3910632_3911967_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	5.0e-29	27.2
WP_089112797.1\|3912126_3912849_+	hybrid sensor histidine kinase/response regulator	NA	NA	NA	NA
WP_022559779.1\|3913246_3913969_-	DNA repair protein RecO	NA	NA	NA	NA
WP_089112798.1\|3914201_3915101_-	GTPase Era	NA	NA	NA	NA
WP_008574282.1\|3915097_3915778_-	ribonuclease III	A0A2K9L8W0	Tupanvirus	1.3e-17	29.5
WP_016850781.1\|3915767_3916175_-	DUF4845 domain-containing protein	NA	NA	NA	NA
WP_007967398.1\|3916175_3916976_-	signal peptidase I	NA	NA	NA	NA
WP_033481242.1\|3917073_3918864_-	elongation factor 4	A0A2K9L6L3	Tupanvirus	1.2e-22	41.2
WP_007962203.1\|3919046_3920624_-\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	1.6e-26	29.9
WP_089112799.1\|3920733_3921627_-	hypothetical protein	NA	NA	NA	NA
WP_007962205.1\|3921623_3922244_-	RNA polymerase sigma factor RpoE	NA	NA	NA	NA
WP_089112800.1\|3922479_3924561_+	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
WP_157768171.1\|3924688_3924826_-	hypothetical protein	NA	NA	NA	NA
WP_089112801.1\|3926190_3927195_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.2e-40	36.8
WP_167382321.1\|3927426_3928230_-	hypothetical protein	NA	NA	NA	NA
WP_089111250.1\|3928306_3929287_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_078586485.1\|3929755_3929959_-	hypothetical protein	NA	NA	NA	NA
WP_089112802.1\|3930099_3931065_-	cation transporter	NA	NA	NA	NA
WP_089112803.1\|3931284_3932187_-	3-hydroxyisobutyrate dehydrogenase	NA	NA	NA	NA
WP_089113585.1\|3932342_3933530_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_089112804.1\|3933529_3934327_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_089112805.1\|3934323_3935505_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_088411881.1\|3935515_3937021_-	CoA-acylating methylmalonate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_089112806.1\|3937159_3938545_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
3938254:3938270	attL	NA	NA	NA	NA
WP_089112807.1\|3939064_3941758_+	TonB-dependent receptor	NA	NA	NA	NA
WP_089112808.1\|3941947_3943159_+	arabinogalactan endo-1,4-beta-galactosidase	NA	NA	NA	NA
WP_078586109.1\|3943155_3945720_+	glycoside hydrolase family 2 protein	L0N6M2	Herpes_simplex_virus	7.3e-29	26.7
WP_042676101.1\|3945957_3946311_-	hypothetical protein	NA	NA	NA	NA
WP_089112809.1\|3946478_3948407_-	alpha-L-fucosidase	NA	NA	NA	NA
WP_089111307.1\|3948536_3949623_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_089112810.1\|3950176_3950413_+\|transposase	transposase	NA	NA	NA	NA
WP_089111250.1\|3952368_3953349_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089111531.1\|3953456_3954600_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-89	58.8
WP_089112813.1\|3956635_3957791_+\|transposase	IS3-like element ISXc8 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.7e-39	37.5
WP_157768175.1\|3957746_3958103_-	hypothetical protein	NA	NA	NA	NA
WP_089111538.1\|3958287_3959518_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	9.9e-133	82.7
WP_089112814.1\|3960576_3961908_-	hypothetical protein	NA	NA	NA	NA
WP_157768177.1\|3962594_3963365_-	hypothetical protein	NA	NA	NA	NA
WP_157768179.1\|3963440_3964037_-	hypothetical protein	NA	NA	NA	NA
WP_089112818.1\|3964033_3965314_-	abortive infection family protein	NA	NA	NA	NA
WP_089112819.1\|3965392_3966805_-	hypothetical protein	NA	NA	NA	NA
WP_089113586.1\|3966797_3967424_-	hypothetical protein	NA	NA	NA	NA
WP_157768181.1\|3967753_3968374_-	hypothetical protein	NA	NA	NA	NA
WP_157768183.1\|3968479_3968686_-	hypothetical protein	NA	NA	NA	NA
WP_089112821.1\|3968764_3969484_-	hypothetical protein	NA	NA	NA	NA
WP_089112822.1\|3969628_3969838_-	hypothetical protein	NA	NA	NA	NA
WP_089112823.1\|3969906_3970386_-	DNA repair protein RadC	NA	NA	NA	NA
WP_089112824.1\|3970784_3971009_-	hypothetical protein	NA	NA	NA	NA
WP_157768185.1\|3971479_3971992_+	hypothetical protein	NA	NA	NA	NA
WP_089112826.1\|3972038_3972686_+	hypothetical protein	NA	NA	NA	NA
WP_089112827.1\|3972722_3973190_-	hypothetical protein	NA	NA	NA	NA
WP_089111307.1\|3974079_3975166_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_089113587.1\|3975175_3975958_+	hypothetical protein	NA	NA	NA	NA
WP_089112828.1\|3976004_3976319_+	hypothetical protein	NA	NA	NA	NA
WP_089113588.1\|3976336_3976696_+	hypothetical protein	NA	NA	NA	NA
WP_016850733.1\|3976756_3977374_-	hypothetical protein	NA	NA	NA	NA
WP_089112829.1\|3977370_3981006_-	wall-associated protein	A0A2H4JFP5	uncultured_Caudovirales_phage	5.9e-08	34.5
WP_089112830.1\|3981002_3983804_-	RHS repeat protein	NA	NA	NA	NA
WP_089112831.1\|3984512_3985250_+	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_157768187.1\|3985975_3986596_-\|integrase	integrase	NA	NA	NA	NA
WP_089112832.1\|3986707_3987505_-	nucleotide-binding protein	NA	NA	NA	NA
WP_089112833.1\|3987497_3989411_-\|integrase	integrase	NA	NA	NA	NA
WP_089112834.1\|3989619_3992235_+	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	1.1e-29	22.8
3991596:3991612	attR	NA	NA	NA	NA
WP_007967453.1\|3992521_3993136_+	DUF937 domain-containing protein	NA	NA	NA	NA
WP_089112835.1\|3993598_3995845_+	catalase/peroxidase HPI	NA	NA	NA	NA
WP_007967457.1\|3995968_3996376_-	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_089112836.1\|3996600_3997257_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_089112837.1\|3997315_3998011_-	YafY family transcriptional regulator	NA	NA	NA	NA
WP_007971118.1\|3998392_3999877_+	MATE family efflux transporter	NA	NA	NA	NA
WP_003484215.1\|4000133_4000541_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_089112839.1\|4000685_4001444_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA

DBSCAN-SWA_13

4169435 : 4231940

Bacillus_phage(12.5%)

integrase,transposase,protease

attL 4194129:4194144|attR 4232378:4232393

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089094916.1\|4169435_4169900_-\|transposase	transposase	NA	NA	NA	NA
WP_007962453.1\|4170122_4170986_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_007972198.1\|4170985_4172113_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_005996155.1\|4172801_4173188_-	response regulator	W8CYM9	Bacillus_phage	5.6e-10	31.8
WP_003483926.1\|4173671_4174571_-	DnaJ domain-containing protein	A0A2L0UZR4	Agrobacterium_phage	7.0e-19	28.0
WP_007962463.1\|4174982_4175459_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_003483924.1\|4175621_4176104_+	peroxiredoxin	A0A1D8KSL1	Synechococcus_phage	7.0e-26	38.3
WP_089112902.1\|4176146_4176707_+	bacterioferritin	NA	NA	NA	NA
WP_089112903.1\|4177055_4179470_-	penicillin-binding protein 1C	NA	NA	NA	NA
WP_007962234.1\|4179906_4180854_-	glycerophosphodiester phosphodiesterase family protein	A0A0S2MYI4	Enterococcus_phage	3.8e-07	36.0
WP_089112904.1\|4184204_4189127_-	alpha-2-macroglobulin family protein	NA	NA	NA	NA
WP_042676284.1\|4190004_4191003_-	nucleoside hydrolase	NA	NA	NA	NA
WP_089112905.1\|4191080_4193297_-	TonB-dependent receptor	NA	NA	NA	NA
WP_007969027.1\|4193511_4194711_-	2-methylaconitate cis-trans isomerase PrpF	NA	NA	NA	NA
4194129:4194144	attL	NA	NA	NA	NA
WP_057661338.1\|4194824_4195382_-	hypothetical protein	NA	NA	NA	NA
WP_089112906.1\|4195391_4197986_-	Fe/S-dependent 2-methylisocitrate dehydratase AcnD	NA	NA	NA	NA
WP_007969021.1\|4198143_4199298_-	2-methylcitrate synthase	NA	NA	NA	NA
WP_007970235.1\|4199373_4200270_-	methylisocitrate lyase	NA	NA	NA	NA
WP_089113594.1\|4200414_4202016_+	propionate catabolism operon regulatory protein PrpR	NA	NA	NA	NA
WP_039732060.1\|4202247_4202574_-	hypothetical protein	NA	NA	NA	NA
WP_003483889.1\|4203204_4203558_-	type IV fimbriae assembly protein	NA	NA	NA	NA
WP_089112907.1\|4203554_4204514_-	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_089112908.1\|4204510_4205584_-	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_089112909.1\|4205644_4207000_-	aminodeoxychorismate synthase component I	NA	NA	NA	NA
WP_042805907.1\|4207165_4208401_-	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_002814322.1\|4208542_4208782_-	acyl carrier protein	B2ZXV3	Ralstonia_phage	5.9e-10	44.6
WP_089094903.1\|4208986_4209730_-	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	3.4e-11	28.9
WP_007969007.1\|4209812_4210757_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_007969006.1\|4211037_4211478_-	MEKHLA domain-containing protein	NA	NA	NA	NA
WP_003483871.1\|4211719_4212697_-	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_089112910.1\|4212751_4212982_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_007969004.1\|4213080_4213590_-	hypothetical protein	NA	NA	NA	NA
WP_042805908.1\|4213702_4214278_+	septum formation inhibitor Maf	NA	NA	NA	NA
WP_167382370.1\|4214569_4216156_-	hypothetical protein	NA	NA	NA	NA
WP_167382325.1\|4216401_4217385_-	glycosyltransferase	NA	NA	NA	NA
WP_089112912.1\|4217405_4219247_-	hypothetical protein	NA	NA	NA	NA
WP_007968997.1\|4219284_4220238_+	MoxR family ATPase	NA	NA	NA	NA
WP_007968996.1\|4220243_4221200_+	DUF58 domain-containing protein	NA	NA	NA	NA
WP_089112913.1\|4221192_4223145_+	DUF3488 domain-containing transglutaminase family protein	NA	NA	NA	NA
WP_007968994.1\|4223141_4223675_+	Slp family lipoprotein	NA	NA	NA	NA
WP_007968993.1\|4223794_4224145_-	histidine triad nucleotide-binding protein	NA	NA	NA	NA
WP_003483843.1\|4224238_4224832_-	recombination protein RecR	NA	NA	NA	NA
WP_005913896.1\|4224929_4225250_-	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_089112914.1\|4225256_4227326_-	DNA polymerase III subunit gamma/tau	E7DN81	Pneumococcus_phage	1.8e-46	41.0
WP_089112915.1\|4227641_4229186_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_089111250.1\|4229381_4230362_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089112917.1\|4230659_4230857_+	hypothetical protein	NA	NA	NA	NA
WP_089111307.1\|4230853_4231940_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
4232378:4232393	attR	NA	NA	NA	NA

DBSCAN-SWA_14

4235984 : 4336481

103

Stenotrophomonas_phage(40.82%)

tail,terminase,plate,protease,head,holin,capsid,portal,integrase,transposase

attL 4295661:4295678|attR 4310813:4310830

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089111307.1\|4235984_4237072_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_089112921.1\|4238251_4238656_-	H-NS histone family protein	NA	NA	NA	NA
WP_089112922.1\|4238732_4238999_-	hypothetical protein	NA	NA	NA	NA
WP_157768191.1\|4239012_4240431_-	TIGR04141 family sporadically distributed protein	NA	NA	NA	NA
WP_089111250.1\|4240531_4241512_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_157768193.1\|4241563_4241830_-	TIGR04141 family sporadically distributed protein	NA	NA	NA	NA
WP_089112925.1\|4242635_4243082_-	molybdenum cofactor biosynthesis protein MoaE	NA	NA	NA	NA
WP_042676279.1\|4243078_4243324_-	MoaD/ThiS family protein	NA	NA	NA	NA
WP_089113596.1\|4243320_4243818_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_007968987.1\|4243843_4244224_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_089112926.1\|4244220_4245252_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_007973306.1\|4245251_4246001_-	MBL fold metallo-hydrolase	A0A0A0RUN7	Bacillus_phage	1.4e-09	26.0
WP_007973307.1\|4246000_4246750_-	3-deoxy-D-manno-octulosonic acid kinase	NA	NA	NA	NA
WP_007973308.1\|4246770_4247820_+	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_007968982.1\|4249156_4249561_-	hypothetical protein	A0A1C9C5K8	Heterosigma_akashiwo_virus	1.5e-16	35.9
WP_007968980.1\|4250103_4250808_+	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_007968978.1\|4251105_4251840_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.5e-35	40.4
WP_005913875.1\|4251848_4252301_-	ribonuclease HI	A0A1Q2U2R0	Vibrio_phage	3.6e-40	55.4
WP_007968977.1\|4252328_4252985_-	hypothetical protein	NA	NA	NA	NA
WP_089112927.1\|4252997_4253765_+	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_089112928.1\|4253761_4254940_+	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_089112929.1\|4255570_4257541_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_002806049.1\|4258179_4258452_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.2e-21	64.0
WP_089112930.1\|4258665_4261137_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	4.9e-224	52.1
WP_003483788.1\|4261281_4262568_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.3e-137	59.9
WP_002806026.1\|4262693_4263320_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.0e-56	57.4
WP_007968966.1\|4263412_4264705_-	trigger factor	NA	NA	NA	NA
WP_089112931.1\|4265234_4266503_+	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_089111250.1\|4266968_4267949_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089112932.1\|4268369_4268801_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_089112933.1\|4269254_4269734_+	peptidase S24	A0A218MND2	uncultured_virus	1.8e-13	37.1
WP_089112934.1\|4269733_4271020_+	Y-family DNA polymerase	I6RSM4	Salmonella_phage	3.7e-82	42.4
WP_157768195.1\|4271959_4272250_+	hypothetical protein	NA	NA	NA	NA
WP_089111538.1\|4272280_4273511_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	9.9e-133	82.7
WP_089112935.1\|4273553_4274405_+	RelA/SpoT domain-containing protein	A0A1B0VBT5	Salmonella_phage	6.4e-22	30.1
WP_039587062.1\|4275226_4276129_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_089112936.1\|4277135_4277552_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_089112937.1\|4277723_4278425_-	site-specific DNA-methyltransferase	V9IQV5	Stenotrophomonas_phage	1.9e-104	75.6
WP_089112938.1\|4278342_4278588_-	Com family DNA-binding transcriptional regulator	V9IQK2	Stenotrophomonas_phage	1.5e-13	51.2
WP_089112939.1\|4278613_4279627_-\|portal	phage portal protein	A0A2H4J922	uncultured_Caudovirales_phage	4.5e-139	71.9
WP_089112940.1\|4279626_4281411_-\|terminase	terminase ATPase subunit family protein	V9IQL5	Stenotrophomonas_phage	9.2e-273	76.7
WP_089112941.1\|4281532_4282375_+\|capsid	GPO family capsid scaffolding protein	A0A2H4J928	uncultured_Caudovirales_phage	3.4e-68	53.5
WP_089112942.1\|4282421_4283441_+\|capsid	phage major capsid protein, P2 family	Q9ZXM3	Pseudomonas_virus	2.1e-136	70.3
WP_089112943.1\|4283444_4284164_+\|terminase	terminase	Q9ZXM2	Pseudomonas_virus	1.3e-68	62.5
WP_089112944.1\|4284262_4284730_+\|head	head completion/stabilization protein	V9IQW6	Stenotrophomonas_phage	1.4e-31	50.3
WP_005917735.1\|4284729_4284939_+\|tail	tail protein	K4PAW7	Burkholderia_phage	7.0e-15	59.4
WP_005929454.1\|4284943_4285300_+	membrane protein	V9IQG9	Stenotrophomonas_phage	3.5e-22	56.1
WP_005922189.1\|4285292_4285568_+\|holin	phage holin family protein	V9IQV8	Stenotrophomonas_phage	1.3e-21	59.8
WP_167382326.1\|4285567_4286206_+	glycoside hydrolase family 19 protein	V9IQK6	Stenotrophomonas_phage	3.8e-51	63.3
WP_039586325.1\|4286205_4286694_+	hypothetical protein	A0A1S5NQ26	Burkholderia_phage	2.0e-20	46.5
WP_039586324.1\|4286690_4287110_+\|tail	phage tail protein	A0A2H4J906	uncultured_Caudovirales_phage	1.1e-40	65.9
WP_039586323.1\|4287097_4287547_+	phage virion morphogenesis protein	V9IQH0	Stenotrophomonas_phage	8.2e-37	54.7
WP_089112946.1\|4287628_4288519_+\|plate	baseplate assembly protein	V9IQV9	Stenotrophomonas_phage	4.2e-85	54.4
WP_089112947.1\|4288511_4289057_+\|tail	phage tail protein I	V9IQK7	Stenotrophomonas_phage	1.1e-51	56.0
WP_089112948.1\|4289069_4290869_+	hypothetical protein	V9IQX0	Stenotrophomonas_phage	2.1e-83	39.0
WP_017167614.1\|4290946_4291240_+	hypothetical protein	NA	NA	NA	NA
WP_089112949.1\|4291241_4291916_+	hypothetical protein	NA	NA	NA	NA
WP_078563111.1\|4292058_4292622_+\|plate	phage baseplate assembly protein V	Q9ZXL0	Pseudomonas_virus	2.4e-25	46.4
WP_089112950.1\|4292618_4292978_+\|plate	baseplate assembly protein	V9IQW0	Stenotrophomonas_phage	2.5e-36	66.1
WP_089112951.1\|4292990_4294157_+\|tail	phage tail sheath protein	E5FFG9	Burkholderia_phage	8.5e-134	63.4
WP_089112952.1\|4294186_4294696_+\|tail	phage major tail tube protein	V9IQX1	Stenotrophomonas_phage	3.1e-72	79.9
WP_017118942.1\|4294741_4295044_+\|tail	phage tail assembly protein	V9IQM4	Stenotrophomonas_phage	2.2e-25	67.4
WP_005922203.1\|4295052_4295166_+\|tail	GpE family phage tail protein	A0A0M4R2P3	Salmonella_phage	4.2e-06	68.6
WP_089112953.1\|4295195_4298066_+\|tail	phage tail tape measure protein	V9IQL1	Stenotrophomonas_phage	4.0e-177	45.3
4295661:4295678	attL	NA	NA	NA	NA
WP_089112954.1\|4298078_4298480_+\|tail	phage tail protein	V9IQX3	Stenotrophomonas_phage	2.7e-39	62.9
WP_089112955.1\|4298476_4299463_+	phage late control D family protein	V9IQM7	Stenotrophomonas_phage	5.9e-88	52.0
WP_157768197.1\|4299550_4300027_+	hypothetical protein	NA	NA	NA	NA
WP_089112956.1\|4300256_4300694_-	transcriptional regulator	E5E3P4	Burkholderia_phage	8.4e-10	34.2
WP_008572763.1\|4300764_4301022_+	DNA-binding protein	A0A2H4JE67	uncultured_Caudovirales_phage	6.6e-07	44.6
WP_008572766.1\|4301024_4301345_+	hypothetical protein	V9IQW3	Stenotrophomonas_phage	2.0e-24	58.7
WP_089112957.1\|4301355_4301634_+	hypothetical protein	NA	NA	NA	NA
WP_008572770.1\|4301630_4301843_+	hypothetical protein	NA	NA	NA	NA
WP_167382327.1\|4301852_4304549_+	toprim domain-containing protein	V9IQW5	Stenotrophomonas_phage	0.0e+00	70.0
WP_015471755.1\|4304872_4305091_+	hypothetical protein	NA	NA	NA	NA
WP_089113598.1\|4305102_4305375_+	hypothetical protein	NA	NA	NA	NA
WP_008572778.1\|4305374_4305647_+	hypothetical protein	NA	NA	NA	NA
WP_089112959.1\|4306140_4306323_+	hypothetical protein	NA	NA	NA	NA
WP_089112960.1\|4306315_4306588_+	hypothetical protein	NA	NA	NA	NA
WP_089112961.1\|4306584_4306809_+	hypothetical protein	NA	NA	NA	NA
WP_167382328.1\|4307501_4308689_+\|integrase	integrase	V9IQN0	Stenotrophomonas_phage	7.3e-125	57.7
WP_089112964.1\|4308692_4309031_-	hypothetical protein	NA	NA	NA	NA
WP_005927840.1\|4309750_4310512_+	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_003483762.1\|4310656_4311664_-	isocitrate dehydrogenase	NA	NA	NA	NA
4310813:4310830	attR	NA	NA	NA	NA
WP_007968963.1\|4311890_4312286_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_033481211.1\|4312282_4312591_-	glutaredoxin 3	A0A2L0UZG6	Agrobacterium_phage	2.7e-07	43.2
WP_033481216.1\|4312740_4314387_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_003483753.1\|4314569_4315259_+	phosphate regulon transcriptional regulatory protein PhoB	W8CYM9	Bacillus_phage	1.0e-33	35.7
WP_167382329.1\|4315331_4316660_+	phosphate regulon sensor histidine kinase PhoR	W8CYF6	Bacillus_phage	1.4e-28	32.9
WP_003483747.1\|4316772_4318875_+	polyphosphate kinase 1	NA	NA	NA	NA
WP_007973706.1\|4319045_4320572_+	exopolyphosphatase	NA	NA	NA	NA
WP_089112966.1\|4320783_4321920_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_007968943.1\|4321900_4322443_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_089112967.1\|4322842_4323586_+	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_007973709.1\|4323774_4324194_-	hypothetical protein	NA	NA	NA	NA
WP_089112968.1\|4324329_4325583_-	peptidase	NA	NA	NA	NA
WP_089112969.1\|4325871_4326696_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_003483730.1\|4326891_4328358_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.1e-85	39.9
WP_089112970.1\|4328388_4329135_-	CvpA family protein	NA	NA	NA	NA
WP_089112971.1\|4329347_4330430_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_089112972.1\|4330497_4331796_-	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_007968929.1\|4332125_4332770_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_089113600.1\|4333525_4334158_-	hypothetical protein	NA	NA	NA	NA
WP_089112974.1\|4334387_4336481_-\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA

DBSCAN-SWA_15

5068367 : 5112709

Shigella_phage(20.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089111531.1\|5068367_5069511_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-89	58.8
WP_089113270.1\|5070640_5071027_-	hypothetical protein	NA	NA	NA	NA
WP_089113636.1\|5071299_5071656_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_089113272.1\|5071895_5072875_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_157768209.1\|5072978_5074517_-	hypothetical protein	NA	NA	NA	NA
WP_089113274.1\|5074740_5075610_-	NmrA/HSCARG family protein	NA	NA	NA	NA
WP_089113275.1\|5075641_5076586_-	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_089113276.1\|5076688_5077564_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_064508114.1\|5077650_5078523_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_089113277.1\|5078715_5079126_+	DoxX family membrane protein	NA	NA	NA	NA
WP_089113278.1\|5079255_5080065_+	hypothetical protein	NA	NA	NA	NA
WP_089113279.1\|5080218_5081289_+	alkene reductase	NA	NA	NA	NA
WP_089113280.1\|5081594_5084258_+	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	6.1e-71	26.9
WP_089111304.1\|5084395_5085376_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_167382345.1\|5086047_5086401_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_089113282.1\|5086873_5088006_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.2e-41	36.8
WP_089113283.1\|5089111_5091532_-	penicillin acylase family protein	NA	NA	NA	NA
WP_089113285.1\|5092563_5093543_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_089113286.1\|5095224_5096130_+	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
WP_089113287.1\|5096388_5097120_-	ComF family protein	NA	NA	NA	NA
WP_022558035.1\|5097163_5098198_+	biotin synthase BioB	NA	NA	NA	NA
WP_057658864.1\|5098289_5099495_+	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_046121141.1\|5099686_5100061_+	hypothetical protein	NA	NA	NA	NA
WP_057658869.1\|5100162_5100924_+	pimeloyl-ACP methyl ester esterase BioH	NA	NA	NA	NA
WP_089113288.1\|5101816_5102701_+	malonyl-ACP O-methyltransferase BioC	NA	NA	NA	NA
WP_007968478.1\|5102949_5103855_+	lipid A hydroxylase LpxO	S4VR59	Pandoravirus	1.2e-37	39.5
WP_007974235.1\|5104025_5104445_-	SnoaL-like domain-containing protein	NA	NA	NA	NA
WP_033481400.1\|5104487_5105105_-	YdcF family protein	NA	NA	NA	NA
WP_089113289.1\|5105089_5106049_-	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_089113290.1\|5106206_5106680_+	hypothetical protein	NA	NA	NA	NA
WP_089113291.1\|5107252_5109157_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_007974239.1\|5109393_5110074_+	DUF2490 domain-containing protein	NA	NA	NA	NA
WP_089113293.1\|5110368_5111337_-	alpha/beta hydrolase	A0A167RJ59	Powai_lake_megavirus	3.1e-25	29.8
WP_089111250.1\|5111728_5112709_-\|transposase	IS5 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022264

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP022263

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection