CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP011036	Pseudoalteromonas nigrifaciens strain KMM 661 chromosome I, complete sequence	3 crisprs	cas14j,c2c9_V-U4,cas5f,cas7f,cas6f,DEDDh,cas3,RT,WYL,csx1,DinG,csa3	2	10
NZ_CP011038	Pseudoalteromonas nigrifaciens strain KMM 661 plasmid unnamed, complete sequence	1 crisprs	NA	1	0
NZ_CP011037	Pseudoalteromonas nigrifaciens strain KMM 661 chromosome II, complete sequence	0 crisprs	c2c9_V-U4,cas14j,csa3,cas3,DinG	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011036_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011036_1

439946-440161

Unclear

Consensus_repeat	Method
TTTTAAAGTGACCTGCCGAGTAGGCAGCTGAGAATG	PILER-CR
GTGACCTGCCGAGTAGGCAGCTGAGAATG	CRISPRCasFinder
GTGACCTGCCGAGTAGGCAGCTGAGAATG	CRT

3 spacers

cas6f,cas7f,cas5f

The CRISPR arrays of NZ_CP011036_1

>merge|NZ_CP011036|1|439946-440161|PILER-CR,CRISPRCasFinder,CRT
TTTTATAGTGACCTGCCGAGTAGGCAGCTGAGAATGCCTTGCTGCGGTGGTGCAGGTGTGTTTTTATGTGACCTGCCGAGTAGGCAGCTGAGAATGATATGCACGGCAATAATACAGCGTTTGCAAAGTGACCTGCCGAGTAGGCAGCTGAGAATGGATTTGGATTACATGCGCCATCGAAATAAAGGTGACCTGCCGTATAGGCAGCTGAAGATA

>NZ_CP011036|1|1|439946-440101|PILER-CR
TTTTATAGTGACCTGCCGAGTAGGCAGCTGAGAATG	CCTTGCTGCGGTGGTGCAGGTGTG
TTTTTATGTGACCTGCCGAGTAGGCAGCTGAGAATG	ATATGCACGGCAATAATACAGCGT
TTGCAAAGTGACCTGCCGAGTAGGCAGCTGAGAATG

>NZ_CP011036|1|1|439953-440161|CRISPRCasFinder
GTGACCTGCCGAGTAGGCAGCTGAGAATG	CCTTGCTGCGGTGGTGCAGGTGTGTTTTTAT
GTGACCTGCCGAGTAGGCAGCTGAGAATG	ATATGCACGGCAATAATACAGCGTTTGCAAA
GTGACCTGCCGAGTAGGCAGCTGAGAATG	GATTTGGATTACATGCGCCATCGAAATAAAG
GTGACCTGCCGTATAGGCAGCTGAAGATA

>NZ_CP011036|1|1|439953-440161|CRT
GTGACCTGCCGAGTAGGCAGCTGAGAATG	CCTTGCTGCGGTGGTGCAGGTGTGTTTTTAT
GTGACCTGCCGAGTAGGCAGCTGAGAATG	ATATGCACGGCAATAATACAGCGTTTGCAAA
GTGACCTGCCGAGTAGGCAGCTGAGAATG	GATTTGGATTACATGCGCCATCGAAATAAAG
GTGACCTGCCGTATAGGCAGCTGAAGATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011036.1\|WP_089367682.1\|444577_445249_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274159
NZ_CP011036.1\|WP_089367669.1\|430881_432072_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293817
NZ_CP011036.1\|WP_089367674.1\|436054_438142_+\|hypothetical-protein	cas5f	cd09736_cas5f_CAS-I-F	gnl\|CDD\|187867
NZ_CP011036.1\|WP_089367680.1\|442488_443469_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011036.1\|WP_089367675.1\|438156_439209_+\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09737_cas7f_CAS-I-F	gnl\|CDD\|187868
NZ_CP011036.1\|WP_089367667.1\|424867_425107_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011036.1\|WP_089367672.1\|433275_434655_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223989
NZ_CP011036.1\|WP_058372459.1\|451501_451933_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP011036.1\|WP_089367673.1\|434820_436050_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377670
NZ_CP011036.1\|WP_089367676.1\|439211_439823_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	pfam09618_cas6f_CAS-I-F	gnl\|CDD\|187870
NZ_CP011036.1\|WP_089367671.1\|432733_433282_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011036.1\|WP_089367686.1\|449328_450873_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463
NZ_CP011036.1\|WP_089367684.1\|446848_448114_-\|S41-family-peptidase	unknown	unknown	gnl\|CDD\|223864
NZ_CP011036.1\|WP_089367678.1\|441176_441641_+\|DUF2059-domain-containing-protein	unknown	unknown	gnl\|CDD\|378261
NZ_CP011036.1\|WP_089367683.1\|446035_446776_-\|divergent-polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|377404
NZ_CP011036.1\|WP_089367670.1\|432228_432537_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP011036.1\|WP_089367681.1\|443461_444574_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011036.1\|WP_089367685.1\|448182_449325_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|227278
NZ_CP011036.1\|WP_089367668.1\|425119_430888_-\|trypsin-like-serine-protease	unknown	unknown	gnl\|CDD\|379142
NZ_CP011036.1\|WP_089367677.1\|440405_440855_-\|DUF2384-domain-containing-protein	unknown	unknown	gnl\|CDD\|131346

Protein	Function_ID	Function_description	E-value
NZ_CP011036.1\|WP_089367669.1\|430881_432072_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293817	cd07731, ComA-like_MBL-fold, Competence protein ComA, ComEC and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes proteins required for natural transformation competence including Neisseria gonorrhoeae ComA, Pseudomonas stutzeri ComA, Bacillus subtilis ComEC (also known as ComE operon protein 3) and Haemophilus influenza ORF2 encoded by the rec-2 gene, as well as Escherichia coli YcaI which does not mediate spontaneous plasmid transformation on nutrient-containing agar plates. It also includes the phosphorylcholine esterase (Pce) domain of choline-binding protein e from streptococcus pneumonia. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. .	1.46287e-09
NZ_CP011036.1\|WP_089367674.1\|436054_438142_+\|hypothetical-protein	gnl\|CDD\|187867	cd09736, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	2.01383e-19
NZ_CP011036.1\|WP_089367675.1\|438156_439209_+\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|187868	cd09737, Csy3_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas7 ortholog.	6.96545e-122
NZ_CP011036.1\|WP_089367672.1\|433275_434655_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	8.20972e-28
NZ_CP011036.1\|WP_058372459.1\|451501_451933_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	3.24284e-25
NZ_CP011036.1\|WP_089367673.1\|434820_436050_+\|hypothetical-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	2.72498e-08
NZ_CP011036.1\|WP_089367676.1\|439211_439823_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|187870	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	1.31296e-43
NZ_CP011036.1\|WP_089367686.1\|449328_450873_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NZ_CP011036.1\|WP_089367684.1\|446848_448114_-\|S41-family-peptidase	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	4.59449e-95
NZ_CP011036.1\|WP_089367678.1\|441176_441641_+\|DUF2059-domain-containing-protein	gnl\|CDD\|378261	pfam09832, DUF2059, Uncharacterized protein conserved in bacteria (DUF2059). This domain, found in various prokaryotic proteins, has no known function.	2.83073e-06
NZ_CP011036.1\|WP_089367683.1\|446035_446776_-\|divergent-polysaccharide-deacetylase-family-protein	gnl\|CDD\|377404	pfam04748, Polysacc_deac_2, Divergent polysaccharide deacetylase. This family is divergently related to pfam01522 (personal obs:Yeats C).	1.96031e-90
NZ_CP011036.1\|WP_089367670.1\|432228_432537_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.98634e-12
NZ_CP011036.1\|WP_089367682.1\|444577_445249_+\|hypothetical-protein	gnl\|CDD\|274159	TIGR02487, Anaerobic_Ribonucleoside-triphosphate_reductase, anaerobic ribonucleoside-triphosphate reductase. This model represents the oxygen-sensitive (anaerobic, class III) ribonucleotide reductase. The mechanism of the enzyme involves a glycine-centered radical, a C-terminal zinc binding site, and a set of conserved active site cysteines and asparagines. This enzyme requires an activating component, NrdG, a radical-SAM domain containing enzyme (TIGR02491). Together the two form an alpha-2/beta-2 heterodimer. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0.00798027
NZ_CP011036.1\|WP_089367685.1\|448182_449325_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	1.1851e-74
NZ_CP011036.1\|WP_089367668.1\|425119_430888_-\|trypsin-like-serine-protease	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	5.70067e-14
NZ_CP011036.1\|WP_089367677.1\|440405_440855_-\|DUF2384-domain-containing-protein	gnl\|CDD\|131346	TIGR02293, conserved_protein_of_unknown_function, putative toxin-antitoxin system antitoxin component, TIGR02293 family. Proteins in this family are found almost exclusively in the Proteobacteria, but also in Gloeobacter violaceus PCC 7421, a cyanobacterium. This family was proposed by Makarova, et al. (2009) to be the antitoxin component of a new class of type 2 toxin-antitoxin system, or addiction module. [Cellular processes, Other].	2.16407e-09

>NZ_CP011036.1|WP_089367676.1|439211_439823_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MQRYYFIVQFLPKQANLALLTGRCISIMHGFILKHNIEGMGVTFPAWSDSSIGNVIAFVHKDMEILNSLKEQAYFVDMQDCGFFKISQILAVPESCKEIRFIRNQAVAKIFTGESRRRLKRLQKRALARGENFNPKKIEAPREVDIFHRVAMTSKSSQEDYILHIQKQNADSQVEPDFSNYGFASNEKFKGTVPDLSPLIESN
>NZ_CP011036.1|WP_089367675.1|438156_439209_+|type-I-F-CRISPR-associated-protein-Csy3
MELCNILKYDRSLYPGKAVFFYKTADSNFVPLEADINKIRGPKYGFTEAFTPQFLPKNISPQDLTHNNILTLEECYVPPNVEHIFCRFSLRVQANSLAPSGCSDPDVFSLLKELAETFKECDGYKELATRYCRNILLGTWLWRNQNTGNTQIEIKTSKGNSYLIDNTRKLAWESKWTSDVQKVLEELSDEIECALTDPNVFWSADITAKIEASFCQEIYPSQILNDKVKQGEASKQFVKAKCADGRYAVSFNSVKIGAALQSIDDWWDEDASKRLRVHEFGADKEIGIARRPPDSEQNFYAIFKNTEWYLSALKNCITNKNENIDPAIYYLFSVLIKGGMFQKKAESKKA
>NZ_CP011036.1|WP_089367674.1|436054_438142_+|hypothetical-protein
MHLKELLEITDITERDRLLRRAFSPYTAMTDITGSEATALIILLNLTYRKNQVDDLLDKQLAKQALKSEDHINKCIKEIAWFHTHNLKYPDIRVSKQNLAVEPPLLHSYVLSSANYPKAYGWSHDSAKVNVAKLFISYFKWQNQVSCLAQVLATNSDNWKAAFTSLGLSVKAFKSLCVTVKKSLPEEAIPDSVDRYSRQIRMPYHDGYLAVTPVISHVVQSRIQQAAIDKRARFSNVEFTRPAAVSMLAASLGGVVNVLNDPPYIRSKYHGLSNSRAFKLNNGQTVFNVEALLKPELIKALEGIIFSNNALALKQRRQQKVKNIKELRNTLLEWFSPVFEWRLDVIENGDDLEQLESASDRLEYKILSLPDDELPSLTIPLFRLLNEMLGGVSMTQRYAFHPKLMSPLKAALQWLLINLTDQKNEPIEVDEEHFRYLHLSGIRVFDAQALSNPYCSGVPSLTAVWGMLHSYQRKLNEALGIKVRFTSFSWFIRDYSAVAGKKLPELSLQGAQQNKLKRPGIIDGKYCDLVFDLIVHVDGYDCDLQVIDSEPDILKAHFPSNFAGGVMHQPELTSNVNWCCLYSNENQLFEKLRRLPLSGCWVMPTDHKIEDLDELLLLLNNDSKLSPSMMGYLLLTEPKARVGALEKLHCYAEPAIGVVKYETAISIRLKGISNYFKTSFWMLDAREKFMLMKKV
>NZ_CP011036.1|WP_089367673.1|434820_436050_+|hypothetical-protein
MTFLFSPKARAFSDESLESYLLRVVSENFFDSYQELSLAIREELHELDFEAHGAFPIDLKRLNVYHAKHNSHFRMRALGLLETLLDLPRYELQKLALLKSDIKFNSSAALYKNGVDIPQKFFRYHAEAAVDSIPVCPQCLAEEAYIKQSWHIKWVDACTKHQCTLAHNCPECCAPINYIENESITHCSCGFELTCASTSPVNALSIEHLNKLLDKSERNDSNPLFSNTTLTECSAALLWYQGRYSQTDNFCLDDAVDYFSMWPAVFYKELDELSKNAEMKLIDLFNKTEFKFIFGDAILACPSTQMQRELHFIYRALLDYLVTLVESNPKTKKPNAADLLVSVLEAATLLGTSVEQVYRLYQDGILQTAFRHKMNQRINPYKGVFFLRQVIEYKTSFGNDKARMYLSAW
>NZ_CP011036.1|WP_089367672.1|433275_434655_+|DEAD/DEAH-box-helicase-family-protein
MLRSWQKECVELAVKKYTASDKHFLCQATPGAGKTIMAALLAKTLFDKGMIDRVICFSPSVEVANNIKRTFGKIIGCSFDGSFTAVGASMTYQSLCSIPESTWDRLRKYRTFFIFDEIHHCSFSQDKSKINTWGERVVFHLQDIATYTLALSGTPWRSDALPIALVSYSNPEGELICDYQYSLIQAIRDNVCREPKIVLVDSNSISDGHDTYGSIAEFVKQAQSTYQEVLNNDSALRYLLKLAVLKLSEIRDSNPIAGGLVVASSVKHAEMINSLLIEEFNQTSTIVTYLHDNSTRKINSFKSSTEQWIVSVGMISEGTDIPRLQVCCHLSSIKTELYFRQVLGRILRSGKGKIEFAWLFTFAETRLVEFAERINIDIPGSCSYVDMECDSISVGEDIFRRFKPPLRDTCSKLKVNIDKLILGDLSSGLNTAYDERLLGCSLSNIQIKSLRTRVIEAFL
>NZ_CP011036.1|WP_089367671.1|432733_433282_+|hypothetical-protein
MPQVIKLNQHIYSLLIEKECNGFTIVELRDELLTVTDTYQDIDEARKFIYRQTTALERKELLNSKGSGRHKKYFKTGLFNNATFVAKQAVIEQEKLSTSNIDNQASPLIETLLNEKKQFEAELAILLGEVDEYKALQKRFPEHLSLFYSALDDAKNNSAKLLGKVNALTTILASLNNDAPQC
>NZ_CP011036.1|WP_089367670.1|432228_432537_-|helix-turn-helix-transcriptional-regulator
MFQNPIPIRLKQARAKSGITQKQLGILIGMDENSASGRMNHYEKGRHIPDLATLKKIADELNVPLNYFFCEDNTTAELVIEISKLDIEKKFELIKQLKATAK
>NZ_CP011036.1|WP_089367669.1|430881_432072_-|MBL-fold-metallo-hydrolase
MKVKMFPAENGDAFLLCSTNINILIDGGYAKTFDKYIKPDLEDLASKGKVLDLVIVTHIDADHIGGIIRFLTLNGIQNLKKIIPINKIWHNSLRSLSSPKKIDVPPEGIDILKAIIKRGHPKESIFKSSNIEEISAKQGCTLAALIREGGYRWNESNGFDSICVEEFSFSETYNDSIKVINPTRAKLQELLLYWKKELRRFGHLDDIGSNEIIDDAFEFNFEHHQDSNITGQTLVAAGCKNELKDVYRPDRSPTNASSIATIVKLDGVRILMLADALAEDILNELIKMQADGESMLFDAIKISHHGSNYNTSPDLLSIIDAPKYFISTNGGGKHNHPDIELLRAIVNRAADFTRTLYFNYSTDASKEIRNFQATYSNFIIEENFTGWIEIIKEKSC
>NZ_CP011036.1|WP_089367668.1|425119_430888_-|trypsin-like-serine-protease
MLDAEAKYATCKVNCGGEQGTGTLITNKVVMTAAHCVNSTIDNKFTIEVVFDFNDKPLALEARVIAYSLDLDIALLELDKDCGIRPISLRSTSPVSGSRFFSYGFPANKLTMGHRLEGNLEQVFDNFKLGSDIEISIDAALSLDNYQGFSGAAIICEGACVGVIRVSIEKTMGAISISAVYDFLNEYGIHIKPEETHKKSSHLISREIFIEEFDSFVCSQINKYIFIKGAHGLGKSVFCETYSPSNSTLEKFGAYSFTTKKSSKNAIQLAQPQEFFNWLNIQVSMLITSNPGRKEILDYQKIIDKTGELFIQLAEFYTLKNKVGILFIDGLDEVERQDAETLNKLIGLMPARLPPGLVIVFSAPNYDQFATRLGNRLSNESCISLPPLNHEPVQAFCYQSLREKHSNSKTVNLICERAQGHPLYLHYLIDLANSGTSADEIKSLPLIEGSIRKYYDIIWMQLREDNDAVNLLAIAVRLRWGIPISHFTDILNSHEQAILISTLGRMQHLLLDNSETTIYHSSFSDFIIEKTQLRERDIQLRLAKHCEEMKLRRYCLLNLIYHNLKAKGAEKTHVMELCNQNWVDDCVYNDVEPDTLIDDLHSVLKVATEQGNLVETVRILLLSQRIQFRYNTLLSQSADLTANALISIDKKQEVIKHISRYGHLIVSFDEALSIALKLIDSNNNEEALELLNIVESHLTENLEAVFKSNGLSYKNFLYIYDLQIQQFLLRVRAGHHSSKLAIANFQHHWMNIIDKTSENEEASKLIRSEMFTYMQTASMCLIDRFITISELQKVYSGPLNELAEPIVFSAYYYQMLCEKYGINQNILLLEQAFSDIKTLISEAWNAQMKVHPNVVDSFILNGAPRDIIIALSKDNSSAPAPINFISSDSVFVDEEALNDGMSEWRMKAFIEANFPRPNLVKLHSETWIVGIKSTLQLIAWCDGSARRFKSTGNIASLESVWNILHVDILNQLKFRLSERAEWIDSYGLPEDILPYIYESIIKLVSDIFPEKAYEILSFIEGQFKHQCGIYSEGFRRILSEVLDIFTRSGLNLEAEDKAFDLVELWLKFVIPNLKNRHELVPDLLKIIPLFTKLGATEKAAETYRLVLAYSMGPNWYKEDQLGLSITALKSQNSELTLPSGSVNQIAGLLDAAGGEMTFQRYVRYAKRDFLSALCSRSDYLNAVNYFIKQTYGTIYQMYQDVTHDDIDRVSKLRGTRFPGTALDEQDSVLVIIESLAPNADWQLCWALLESYQFGDSRYITRFAEVYGLLIDKVSEDDKSMSLIIDRLEIICESEFSNKSNCSEFIASIAPFIPEQYKNIFEDKFCELLAVSSTGKFKVQTAEEKKDKVDNIGNQQAEETSDLLYMPGTFGRKDSIDEAATAFSNAERFLRRQNYSEGQKEIISGLNSIQTAGWPIWAGQMSESVVAQSLLLETTNSVTNLIKLYSPLILNERYADNWRIADCLIKWLTSHSSDNEQLELIRVTCEHTKLMVGNINEETAIFSSHDNMKESSNCLVTLLLHAIEHPSWQRREKASDMLIWLSQSFSKFVHLFGAKAFTMDSGAHPDLICGALEQLSSSSPKLWETLSKELDFCFIEKNCKHLGRYSVLVKLARDAASKELESAEEALNTLMTRFDCVGADKDKKNYIELPSWAECISDKWEKLNSLGFLSTGVVTEAESILKVICSSFSANISLELEQLLAEGYYGNVKNPVRWQDKVCFVLQVALQNFRDESDYKKIESIFRKYNPSRLDNLRVKKFKSPALHWLESKKISPMQEDIIFLDYCERVFFQGKLRLVRLTAYLSDKPNEISLPSGRFLSVDKPMLDNTSLLDTCANVSPLPAYFGSFTPAIPTTDFMRNTNSSSSSIKRAWWRSGRLKDTYKGAPSHEGCFLSIKASSLQLPQGFKLIWIFELDHKPVSIISFG
>NZ_CP011036.1|WP_089367667.1|424867_425107_-|hypothetical-protein
MNFETYDTPRTRLEFELRFHYLHSTMKKGKFSVSADVSIEGILNVRKLPNGRIDFLSVNESARLHANTVFHMRNFKPPE
>NZ_CP011036.1|WP_089367677.1|440405_440855_-|DUF2384-domain-containing-protein
MPSYIQPSANRKFVEILSDGTINLNSNPLDEIELIQRGLDINCVEKFRLELRWDLQSFTKAIGTNTKAFERYIKEHKRLNVTLSENIVELAHLASACIDYFESVERWTTWLNTRSLQFSSEMPLTFVNTIAGRELIKKTVDSLNHGYNA
>NZ_CP011036.1|WP_089367678.1|441176_441641_+|DUF2059-domain-containing-protein
MKKLLLIVLLLPFFINANELVFKLLEVNGAKAFFAQSKGQMAKVMYMTDPSLKPYSGLVEKWEEDYFSWEKVKLSIAPIYSSKFTNSELEEIVNFYTTGKPDSFLVTNTGKKFQSLLPEINQEFTMNGHKYMSHVSPFLYEAVSNSTKSLKQDK
>NZ_CP011036.1|WP_089367680.1|442488_443469_+|hypothetical-protein
MAETGNIEKLAKLVSKDIFKWFKWETCLPKDENWECVTEHHGKTTHPSDVVFYYDDPYSGDTKYLNTDLKSYKAGSINTSSVSKALKSLAMSVECANISESWQSTFLLDDVGFGSVAGLLFIYNHDDKYDYDFSDLMGRVGFREIPLLEDKEIVVMGPHLIKRLCDVVSDMQKLKADDSFPSPKDFTFFYPDLIRARRCGDEWDKPATVEALTSPWLIIKHRSGDDFDSGFVIYYHQSGETVDEFIYLIDAMSHYQMLSSDYTIRVRFTDASKHASVNFEKAKREYLKMWGNDDAREKQMTVIEAETITKFTTCFNPMEIGMREDV
>NZ_CP011036.1|WP_089367681.1|443461_444574_+|hypothetical-protein
MSKLRTGPSIYIPTDKNIFDALQHKKVTHSELVLFLRGRGILVSSSTSKDALIEKISSLALSYSDFNWIGKLLENPNRKDKTTHSKLKGEIEDSQIQAACSAVKANLTAIGDDSVKVTKSGDTTTLTVSYVDHDFTKTEMRQRTLKTCEIKLEKGKDGVVMKLPSTKKAKEVSETLKKAVQAQVIKDTGTELEEFSISLQSITNASCRSEFFDSLIRNVPDFKFDNVSSVDVYHLEQEEKDELDEDDTVEARLASYINKAALAGEGVLDSTEFKQLHKRGFYIYKIIWTAIDRTHEGPKVEFEACFGRPDLCTEFMYTVRGLYPYNSRTLEYNVTRKAATPYENEKYNVNLRDASEKALAKTIEAYDKKV
>NZ_CP011036.1|WP_089367682.1|444577_445249_+|hypothetical-protein
MIKAKWLYSELPLTLTELSRLMKEQQYSEETGLGFLLSVSTPSKLSGKYVEKQVQRSVVEDPFGEVTEIESVSYYTCQFNWSSSSKYMYITNPPRSLRKFLNKLHEMTGLGLVLSEVNVAPERWVGYLERASDSLKVTQLSSYGIRVSQGASAKITVNGIKDIRDDFSTIISDKRYLVDSVKFKAEFGSLELLCELTRLGVCRLKSANVNFVLDKLREALEGV
>NZ_CP011036.1|WP_089367683.1|446035_446776_-|divergent-polysaccharide-deacetylase-family-protein
MKVIIGLILMLGFASLNAKAKQIAIVIDDIGYHQRDLELLTLPGQVSYSILPHTPYAQAFATLASKTNKELLLHIPMQALNGKELGPGALTLNMNKEQIQQILGTALASLPQVKGVNNHMGSALTQQGQAMRWIMEVLKKRHLYFLDSRTTELSQAQNAANFLGVENIGRHIFLDNITTREQLQLRLDELKQHATEHKFAIAIAHPYPETIAFLRHVLPQLSKQGFELVPVSKLVERKYIQLAEKR
>NZ_CP011036.1|WP_089367684.1|446848_448114_-|S41-family-peptidase
MDKKSTEAKWFKNTGFTLNLSLYLLALLIFISFSANVFSSSIKELKSQQITEILFNIHTYYVEDLALQNTTHTSYNNQQFAHLYAQLDPYSKYLDEHELNTLFDNTNGRYTGLGIEVKQINNSVTIVNVVSNSPAKSAGVMAGDIIISVNNQTTQNSTVEHVAQLITASKLSNISLTIKRDNQPQPLNFNVSRRKIKLESVTSQRLDLGSGYLAINSFSNHTLHEVALQIAAMQNHFGDPLKGLVIDLRDNPGGTLRSAVAVSDLFLQNGTIVTTKGRYNEANKAFYAKHGDILKGAPIVVLINENSASAAEILAAALKDNNRAKVVGSQSFGKGSVQSLIPLGDGSTALKLTTAKYFTPLGKSIEGVGITPDVAINQTTLSQSDKAVIIKNQQAKSKQTQLASKVTDLQLAKAKQLLNLQ
>NZ_CP011036.1|WP_089367685.1|448182_449325_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MQKCINSVTKLILILTFLATATAVANEDRTKKDLSEVQTALKQSQSEYNAQRKKVATLQKNLQQHELEIAKNAKALNMAEQSIKKTEQQQQLQQQKADQLEQQHAQFQHALAAQLKSAYMAGGDDDYAKMLLNQEDTAKFERTLSYYNYLNKARIEQLEELKALQLQIAKNQAELAKTKQKLVNLHDEQKRRQTALVSAQSERQANLKNLQAQLNSTKSSINYLKENQQTLITTIEELEKEKNKKVELLGLNNSKGKLNWPSRGKLEHTFGQRKHGGIDWKGVLIGAKEGSNINSVHNGQVVFADWLKGYGWVIVVDHGEGFMSLYGHAQTLLKDVGDMVREGETVALVGQSGGQASSGLYFEMRHKGRAVNPEKWCKRI
>NZ_CP011036.1|WP_089367686.1|449328_450873_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSEHKKPLVLMILDGWGYREDEQSNAILAANTPVLDELWATRPRTLISASGFDVGLPDGQMGNSEVGHVNLGAGRVVYQDFTRITKAINDGEFDSTPALVDNIDKAVSADKAVHIMGLLSPGGVHSHEDHIVASIELAAKRGAKEVYFHGFLDGRDTPPRSAKASIERIEAVFAKLQCGRLASLIGRYYAMDRDNRWNRVEKAYNLLTLAQGDFSYPTGVSALEAAYERDENDEFVAASTITPAGAEPVQINDGDTVIFANFRADRAREITRAFVEPNFDGFAKQKSPALSAFVMMTEYAADIDAPVAFGPTPLVNVLGEWFEKHGKTQLRISETEKYAHVTFFFSGGREDEFNGETRELIPSPQVATYDLQPEMNSEMLTDKLVAAIKSGKYDAIICNYPNGDMVGHSGVFAAAVKACEAVDHCIGRVVAALNEYGGEALITADHGNAEQMANLKTGQAHTAHTSEPVPFIYVGRDATPSEGKALSDVAPTMLHLMGMEQPTEMTGKPIMTLK
>NZ_CP011036.1|WP_058372459.1|451501_451933_+|rhodanese-like-domain-containing-protein
MDQYIEFITNHPILSAAWVGIVFLIVSGWIKSKLSAVRQINPQQLTLLINREDGQVIDMRAQKEFNTGHIAGAQHLSPENAKKSDFSSLEKYKSKPIILVCTTGMTASGTATAMHKAGFEQVSVLSGGMGAWQSASLPTTTGR

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Crispr_ID: NZ_CP011036_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011036_2

459818-459923

Orphan

Consensus_repeat	Method
TGCGCGAGGTAAACTCCCGCCTAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011036_2

>merge|NZ_CP011036|2|459818-459923|CRISPRCasFinder
TGCGCGAGGTAAACTCCCGCCTACGGGTTGGGGGTTTATTGTAGGCGGGGCTTTATGCCGCCTAGTTAAACTCTAAAACTATTGCGCGAGGTAAACTCCCGCCTAC

>NZ_CP011036|2|2|459818-459923|CRISPRCasFinder
TGCGCGAGGTAAACTCCCGCCTAC	GGGTTGGGGGTTTATTGTAGGCGGGGCTTTATGCCGCCTAGTTAAACTCTAAAACTAT
TGCGCGAGGTAAACTCCCGCCTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011036.1\|WP_089367696.1\|468327_469173_-\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|181612
NZ_CP011036.1\|WP_083497533.1\|454568_455435_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|181919
NZ_CP011036.1\|WP_089367694.1\|465748_466966_-\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|224376
NZ_CP011036.1\|WP_089368925.1\|467437_467854_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|236718
NZ_CP011036.1\|WP_089367691.1\|462692_463325_-\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NZ_CP011036.1\|WP_058372459.1\|451501_451933_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP011036.1\|WP_089367689.1\|458114_458804_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP011036.1\|WP_089367692.1\|463326_464247_-\|prepilin-peptidase	unknown	unknown	gnl\|CDD\|224900
NZ_CP011036.1\|WP_011327088.1\|459995_460226_-\|DNA-gyrase-inhibitor-YacG	unknown	unknown	gnl\|CDD\|234754
NZ_CP011036.1\|WP_086996570.1\|458968_459454_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197366
NZ_CP011036.1\|WP_089367662.1\|469399_470946_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP011036.1\|WP_089367690.1\|460898_462572_-\|type-IV-A-pilus-assembly-ATPase-PilB	unknown	unknown	gnl\|CDD\|274186
NZ_CP011036.1\|WP_086996610.1\|451964_452222_+\|glutaredoxin-3	unknown	unknown	gnl\|CDD\|274017
NZ_CP011036.1\|WP_089367688.1\|456721_458137_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236532
NZ_CP011036.1\|WP_058372461.1\|452754_453762_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NZ_CP011036.1\|WP_089367687.1\|455785_456718_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|182697
NZ_CP011036.1\|WP_011327082.1\|453943_454408_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|182406
NZ_CP011036.1\|WP_089367693.1\|464704_465088_-\|GxxExxY-protein	unknown	unknown	gnl\|CDD\|372581
NZ_CP011036.1\|WP_011327080.1\|452262_452751_+\|protein-export-chaperone-SecB	unknown	unknown	gnl\|CDD\|180234
NZ_CP011036.1\|WP_089367695.1\|466976_467417_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|236718

Protein	Function_ID	Function_description	E-value
NZ_CP011036.1\|WP_089367696.1\|468327_469173_-\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|181612	PRK09016, PRK09016, carboxylating nicotinate-nucleotide diphosphorylase.	3.17213e-147
NZ_CP011036.1\|WP_083497533.1\|454568_455435_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|181919	PRK09509, fieF, CDF family cation-efflux pump FieF.	1.68946e-104
NZ_CP011036.1\|WP_089367694.1\|465748_466966_-\|type-II-secretion-system-F-family-protein	gnl\|CDD\|224376	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion].	1.86852e-143
NZ_CP011036.1\|WP_089368925.1\|467437_467854_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|236718	PRK10574, PRK10574, putative major pilin subunit; Provisional.	1.32127e-22
NZ_CP011036.1\|WP_089367691.1\|462692_463325_-\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	2.15218e-92
NZ_CP011036.1\|WP_058372459.1\|451501_451933_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	3.24284e-25
NZ_CP011036.1\|WP_089367689.1\|458114_458804_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.17729e-82
NZ_CP011036.1\|WP_089367692.1\|463326_464247_-\|prepilin-peptidase	gnl\|CDD\|224900	COG1989, PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.01917e-43
NZ_CP011036.1\|WP_011327088.1\|459995_460226_-\|DNA-gyrase-inhibitor-YacG	gnl\|CDD\|234754	PRK00418, PRK00418, DNA gyrase inhibitor YacG.	7.22153e-24
NZ_CP011036.1\|WP_086996570.1\|458968_459454_+\|hypothetical-protein	gnl\|CDD\|197366	cd09916, CpxP_like, CpxP component of the bacterial Cpx-two-component system and related proteins. This family summarizes bacterial proteins related to CpxP, a periplasmic protein that forms part of a two-component system which acts as a global modulator of cell-envelope stress in gram-negative bacteria. CpxP aids in combating extracytoplasmic protein-mediated toxicity, and may also be involved in the response to alkaline pH. Functioning as a dimer, it inhibits activation of the kinase CpxA, but also plays a vital role in the quality control system of P pili. It has been suggested that CpxP directly interacts with CpxA via its concave polar surface. Another member of this family, Spy, is also a periplasmic protein that may be involved in the response to stress. The homology between CpxP and Spy suggests similar functions. A characteristic 5-residue sequence motif LTXXQ is found repeated twice in many members of this family.	7.59826e-15
NZ_CP011036.1\|WP_089367662.1\|469399_470946_-\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.89442e-22
NZ_CP011036.1\|WP_089367690.1\|460898_462572_-\|type-IV-A-pilus-assembly-ATPase-PilB	gnl\|CDD\|274186	TIGR02538, Type_IV_pilus_assembly_protein_PilF, type IV-A pilus assembly ATPase PilB. This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP011036.1\|WP_086996610.1\|451964_452222_+\|glutaredoxin-3	gnl\|CDD\|274017	TIGR02181, GRX_bact, Glutaredoxin, GrxC family. Glutaredoxins are thioltransferases (disulfide reductases) which utilize glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. Together these components compose the glutathione system. Glutaredoxins utilize the CXXC motif common to thioredoxins and are involved in multiple cellular processes including protection from redox stress, reduction of critical enzymes such as ribonucleotide reductase and the generation of reduced sulfur for iron sulfur cluster formation. Glutaredoxins are capable of reduction of mixed disulfides of glutathione as well as the formation of glutathione mixed disulfides. This family of glutaredoxins includes the E. coli protein GrxC (Grx3) which appears to have a secondary role in reducing ribonucleotide reductase (in the absence of GrxA) possibly indicating a role in the reduction of other protein disulfides. [Energy metabolism, Electron transport].	4.73594e-39
NZ_CP011036.1\|WP_089367688.1\|456721_458137_-\|HAMP-domain-containing-protein	gnl\|CDD\|236532	PRK09470, cpxA, envelope stress sensor histidine kinase CpxA.	5.39511e-86
NZ_CP011036.1\|WP_058372461.1\|452754_453762_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	0
NZ_CP011036.1\|WP_089367687.1\|455785_456718_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|182697	PRK10749, PRK10749, lysophospholipase L2; Provisional.	1.08195e-56
NZ_CP011036.1\|WP_011327082.1\|453943_454408_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|182406	PRK10358, PRK10358, tRNA (uridine(34)/cytosine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase TrmL.	9.6057e-89
NZ_CP011036.1\|WP_089367693.1\|464704_465088_-\|GxxExxY-protein	gnl\|CDD\|372581	pfam13366, PDDEXK_3, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	7.55312e-54
NZ_CP011036.1\|WP_011327080.1\|452262_452751_+\|protein-export-chaperone-SecB	gnl\|CDD\|180234	PRK05751, PRK05751, preprotein translocase subunit SecB; Validated.	2.93269e-85
NZ_CP011036.1\|WP_089367695.1\|466976_467417_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|236718	PRK10574, PRK10574, putative major pilin subunit; Provisional.	2.39658e-17

>NZ_CP011036.1|WP_086996570.1|458968_459454_+|hypothetical-protein
MTKVNTLSKLVLICGLATATFGATSVMAKGDMHKQGRHSQAHFLLSERGADKLDLTQEQQTKLEAIFAAQKTQMQALKGTDKEARKAQRTAHKAKMESLLSAATFDENAAKELLAQRHEKGEEMGLIKLKTQHQVWQVLNAEQQEKFAKMQKRMGKKKHSK
>NZ_CP011036.1|WP_089367689.1|458114_458804_-|response-regulator-transcription-factor
MKLLMIDDDTGLCELLSEYLTAQGFNVQSVHDGEQGLKLAQANDYALILLDVMLPTLDGFEVLKQLRQTKLTPVIMLTAKGEDFDRIFGLELGADDYIPKPFNHRELLARVKAITRRIEHITTMNATSNNKLVVNGVTINLAAREALIKQTTLTLTGTEYEILALLAKRAGEVVSKEQISEDVLGRRLASFDRSIDMHVSNIRKKIAEHLPNELIKTIRGTGYVFIQGE
>NZ_CP011036.1|WP_089367688.1|456721_458137_-|HAMP-domain-containing-protein
MSLFKANKLASFSWLKHPRHYLFFKIFTWFWLTIIGTGAALIFLSSVTTINSVSYNPLHGPMEKNLAYTAKNIERSTIKHKRSLNDTLKHPRRTNGKLLYLNAEQLEDSLTNKSIPADVDLSLLNFTKSMPPQVIYTEKYQAIGPIKIRVPEGDFYLYEIDIYNHTPLYLRLKLMPGWIKISIAIIASLILSFLFSRNLIAPINSLKKAAIKLSAGDLTARAAISANRKDELGILGRDFNRMADQLAQLISAQKRLLADISHELRSPLTRLKMATGLAQMQANEASQSYLLRIEKEANQLDKMIADVLQVSRLEANSQALSLHKQSLQDIVDHVLNDATFEAKQHNKQLQVSGSAAVTLNCDEALIASALENLLRNAIKYAQHTISLTLKHGDAIYIEICDDGPGVPNNQLSKLCEPFFRQSDARDRVSGGTGLGLAIAKNAIIAHGGSLILSNKPQGGLCAMVTLPIIKE
>NZ_CP011036.1|WP_089367687.1|455785_456718_-|alpha/beta-fold-hydrolase
MFYSSENELIDNQPSINDFYNNTLVKAYLNTPAGQLFYAYAKPEHAHTAIVISSGRIEGLDKYKELLWELYTNNFAVFIVDHQGQGRSYRQLANKHKGYVKCFTDYRHDLHLFNQQIVDNHWQGKKILLGHSMGGAIAFDYLAHFENSFSGLFLSAPMFDIHTKNTPKPLAKLIANAAVFFGFSQSYALGQNDYSPEEFALNSLTSSQVRYKNFRQTYQDPLLQLGGVTYGWLQAAFTFIASVDKLSINIPLFIASAERDEVVDNTAQYKLANRHNQAIIKSFAGAKHELLFERDEIRQPLLTSLYQFCE
>NZ_CP011036.1|WP_083497533.1|454568_455435_+|cation-diffusion-facilitator-family-transporter
MVMVSLMIAAKTWAWLASGSASMLGSLTDSLMDITATAMSFLVLGYALRPADDDHRFGHGKAEALAGLGQAAFIAGSGCLLAFHSIERLFNPLELTHSLLGVWVSIFAIACTLVIVFVQNKVVKHTESIAIKADSVHYKGDLILNAAVLLAILLSYYGVLYADPIFAVGVAGYLLYNSWDIARDSADHLMDKELPDEEKQRILDVSKSHTDVRGVHGVRTRQGGKVKFIQLHLELDDHLSLIRAHNVADEVEAMITKEFESEVDILIHLDPLSSVELSDTEGAAVTEP
>NZ_CP011036.1|WP_011327082.1|453943_454408_-|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MLDIVLYQPEIPPNTGNIIRLCANTGYSLHLIEPLGFAWDDKRIKRAGLDYHEFSHVQRHASFEAYLEACKPKKIYACTTKGSQFHHQAQYEAGDCLVFGPETRGLPDELIQSLPNEQRVRIPMQANSRSMNLSNAVSVFVYESWRQLGFPGAK
>NZ_CP011036.1|WP_058372461.1|452754_453762_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MSTATSAVTVLGAGSYGTALAICLARNGHQVTLWGRNSDDVATLAAERKNQRYLPDIPFPDTLTLEADLQRAAASNEIVLVVVPSHAFGDTLKQIKPALQQGAKVAWATKGLEPNTGRLLQEVAVQELGDAIPLAVLSGPTFAKEMAMGSPTAISVSSTSTEFAKQLADLLHCGRSFRVYNNDDFIGIQLGGAVKNVIAIGAGISDGVGFGANARTALITRGLAELTRLGCALGAKPETFMGMAGLGDLILTCTDNQSRNRRFGLALGKGESVEAAIESIGQVVEGFRNTKEVYLLAQRSGVEMPITEQIYKVLYENKDMKEAAMALLGREQRSE
>NZ_CP011036.1|WP_011327080.1|452262_452751_+|protein-export-chaperone-SecB
MNEETQNAAAQQETGAQFTIQRIYTKDVSFETPNSPAIFQKEWTPEVKLDLDTRSNKLDEGVFEVVLALTVTASIGEETAFLCEIQQAGIFTIADVEETQLAHMLGAFCPNVLFPYAREAVSNLVNRGTFPQLNLAPVNFDALFAQYMQQRTAQAEQASVDA
>NZ_CP011036.1|WP_086996610.1|451964_452222_+|glutaredoxin-3
MSNVVLYTKAYCPFCQRARALLDSKGVQYTNFDIGVQPELRDEMIAKAGGASTVPQIFINDEHIGGCDDMMAIEAQGQLDKKLNA
>NZ_CP011036.1|WP_058372459.1|451501_451933_+|rhodanese-like-domain-containing-protein
MDQYIEFITNHPILSAAWVGIVFLIVSGWIKSKLSAVRQINPQQLTLLINREDGQVIDMRAQKEFNTGHIAGAQHLSPENAKKSDFSSLEKYKSKPIILVCTTGMTASGTATAMHKAGFEQVSVLSGGMGAWQSASLPTTTGR
>NZ_CP011036.1|WP_011327088.1|459995_460226_-|DNA-gyrase-inhibitor-YacG
MPTIVNCPTCKSKVEWSEQSPHRPFCSKRCQLIDLGEWSFENNRISAPITSAEDFSQDMIEDIEAMMAKNEDDFFK
>NZ_CP011036.1|WP_089367690.1|460898_462572_-|type-IV-A-pilus-assembly-ATPase-PilB
MNINSPLLRKFITLGRVDADIVKTKQQEFASTAELIAKCGKIESKDLAAQCIDLFRVPFFDLKDFNTALISPELIKEKLIRKHHILPLVQKGRKVYIAASDPTDYGAFENFEFSTGLSCEVVVVDYIQLDKKIEQLLDATGSLNLSDDEFKEFAELDADIQKDTSKDDDKDDAPIIVYINKILMDAIKKGASDLHFEPYEHKYRIRFRIDGILHEVASPPNTLATKLSARIKVMSRLDIAEKRKPQDGRIKLKITERKSVDFRVSTMPTLWGEKIVMRILDSSSAMLGIDVLGYEPEQKKLYMDALEQPQGMILVTGPTGSGKTVSLYTGLNILNQPERNISTAEDPVEINLEGVNQVQINIKADMTFANALRAFLRQDPDVVMVGEIRDLETAEISIKAAQTGHLVLSTLHTNSAPETITRLLNMGVPAYNVASSISLIIAQRLARRLCPKCKTPENLPSEELLRQGFSQQQISEMTLYAPKGCENCTDGYKGRVGIYEVMKITPEIAQIIMRGGNSLEIAEVSLKAGFNNLRLSGIRKAADGMTSLAEINRVTSF
>NZ_CP011036.1|WP_089367691.1|462692_463325_-|dephospho-CoA-kinase
MSEQTVKVTNINNWVLGLTGGIGCGKTAVSNMLEALGICVVDADIIARQVVEPGSAGLKAIVAHFGADILLADGNLNRSALRKLVFSNTEHKNWLNTLLHPLIRQQIITDLNNATSPYVVLVAPLLFENGLDKYCNRTLLIDVPKNVQIERTVKRDNISLEQVNSIIAAQMSREHKQQQADDILNNDRSLTLVKHDLIALHKGYLKLALK
>NZ_CP011036.1|WP_089367692.1|463326_464247_-|prepilin-peptidase
MQSFFLDITTVMQSQLWFYLTTIGLVSLCVGSFLNVVIYRLPLMIQREWQGECRLLLESELKSNKANTNEPFSSGLNSTFNLVKPNSTCPKCKTAIKAWQNIPIISWLFLKGQCASCSNPISARYPIVEAITALLSLVVAYKLGATEQALLYIAITWALVALTFIDIDHMLLPDQITLPLVWLALIAAVLGYTVNPTDAIIGAACGYLSLWSVFWLFKLLTGKEGMGYGDFKLLAVFGALLGWQSLLIIILLSSVVGAIIGIALLTIQGKDKATPIPFGPYLAIAGWITMLWGEQLQASYFNLIGY
>NZ_CP011036.1|WP_089367693.1|464704_465088_-|GxxExxY-protein
MEIDLLTQKVIGCAIEVHNQLGPGLLESSYEKCFIYELQQAGIVAKSQVELSINYKNILIDAGYRLDILLPNQLIIELKAVDKLQPIHSAQLLTYMKLTSISSGLLINFNVKKLTDGVKRFNLPKGE
>NZ_CP011036.1|WP_089367694.1|465748_466966_-|type-II-secretion-system-F-family-protein
MKKNSDLDTFQWIGVSTRGKRLEGEMTGASIALVKAQLRKQGITPSKVKRKAKPLFGVRMQAITPKDIALVTRQIATMLMAGVPLIQSIEMIGSGSSNKSVSKLMETIADEVKAGQPLSQALRRHPRYFDDLYCDLVASGEQSGALDKIFDRVAIYKEKSEALKSKIKKAMFYPIAVLVIALIVTSILLIFVVPQFQDIFSGFGAELPAFTLMVIGISEFMQEYWWMMLIVIVAFGWAFKEAHLKSLKLRDATDRAILKLPVIGMILNKAAVARYARTLSTTFAAGVPLVDALDSAAGASGNAVYRYAILEIKAEVSSGNQMNWAMRNSKIFPDMVIQMVAIGEESGSLDSMLGKVATIYEQEVDDAVDGLSSLLEPMIMAVLGVLVGGLIIAMYLPIFQLGSVI
>NZ_CP011036.1|WP_089367695.1|466976_467417_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MNIYNVINKPKGFTLIEMLITLAIIGLLASIAIPQYNLYLNRAKFSEVILATSIYKNSIEIAFATNSYTSLDEFDGGNLGIPENNSPQIIPHKHIANSTVINGVIYIESSISLDGSNVTYILTPTISAKNTLSWNTTGSCIDAGLC
>NZ_CP011036.1|WP_089368925.1|467437_467854_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MTQQSQKGFTLIELMIVVAIIGILAAVALPAYQNYTNRAKFAEAVLAVTPYKTAMELAIQTKNITAKTDLNAATFGIPADIALTANDHGVVAADGVITVTWKTDKSPLDGVTYTLTADGVTPPVNWAEGGTCLTNGFC
>NZ_CP011036.1|WP_089367696.1|468327_469173_-|carboxylating-nicotinate-nucleotide-diphosphorylase
MPIPHTLVSQLVTLALGEDLNYQSAENGDITAQLIPANEQANAKVITREDCIFCGKDLIIEVFKQVDPSVVVNVLVNDGDAVKANSTLFTATGSARAILTAERTALNFVQTLSGTATTTAHYVKELAGTKTQLLDTRKTIPGLRILQKYAVKCGGGANHRIGLYDAFLIKENHIAACGGINKAVAQAKQNQPNKPIEVEVESLVDLKQALDAGADIIMLDNFNVEQIKQAVVVTNKRAKLEVSGNMTLETLRTYSQAGVDFISSGALTKNLQSIDLSMRFE
>NZ_CP011036.1|WP_089367662.1|469399_470946_-|IS3-family-transposase
MRRQFTQEFKVQAVEKALSQCDDVRLEDIADDLGVGYSTLQRWIALAKKHQLETHQTGSQMTAEKRPQDWSLEERLSAIIDCGHLDETAINEYCRNKGLYPHHIKQWKQDFAQGPTTKLAKSDSKQLKQEIKQLQKELNRKDKALAETAALLVLKKKADAPLGFQRGRLTTATERHELITLITNAQASGARKEKACELLGLTLRTVQRWIEADDMTDKRTSTKKQPPNRLTELERQRIINTVNSAEYGHLPASKIVPKLLDKGIWIASESSFYRVMKAHNLLTHREKVKPAKPMKKPRALKAVRANEVYTWDITYLPTSVKGQFLYLYLVMDIFSRKVVGWQVYDTQLSELAADLMKDICSREQIKREQVTLHSDNGSPMKGATLLATLQELGIVPSFSRPSVSNDNPYSESLFKTLKYRPEYPEKAFEDISAAREWVSGFVDWYNNEHLHSGIKFVTPNQRHSGLDKEILAKRQQVNDAAKLNNPSRWSGKSRDWSMINEVNLNPEKKEEMRAA

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Crispr_ID: NZ_CP011036_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011036_3

573909-574161

Unclear

Consensus_repeat	Method
AATTACTGACTACTTTATAATGCGGTACTAGCTCAGTTGGTAGAGCGCGACCTTGCCAAGG	PILER-CR

2 spacers

DEDDh

The CRISPR arrays of NZ_CP011036_3

>merge|NZ_CP011036|3|573909-574161|PILER-CR
AATTACTGACTACTTTATAATGCGGCACTAGCTCAGTTGGTAGAGCGCGACCTTGCCAAGGTCGAGGTCACGAGTTCGAGCCTCGTGTGCCGCTCCAATTTCTAACCAAAAGAAATTGCAGTGTTGAATAAAAATGCGGTACTAGTTCAGTTGCCAGAATGTTGAACGCGATTTTTCGCGCACCAACGGACGAATTACTGACTACTTTATAATGCGGTACTAGCTCAGTTGGTAGAGCGCGACCTTGCCAAGG

>NZ_CP011036|3|2|573909-574161|PILER-CR
AATTACTGACTACTTTATAATGCGGCACTAGCTCAGTTGGTAGAGCGCGACCTTGCCAAGG	TCGAGGTCACGAGTTCGAGCCTCGTGTGCCGCTCCAATTTCTAACCAAAAGAAATTGCAGTGTTGAATA
AAAATGCGGTACTAGTTCAGTTGCCAGAATGTTGAACGCGATTTTTCGCGCACCAACGGAC	GAATTACTGACTACTTTATAATGCGGTACTAGCTCAGTT
GGTAGAGCGCGACCTTGCCAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011036.1\|WP_086993126.1\|570008_570755_+\|HesA/MoeB/ThiF-family-protein	unknown	unknown	gnl\|CDD\|238386
NZ_CP011036.1\|WP_011327196.1\|571825_572884_-\|small-ribosomal-subunit-biogenesis-GTPase-RsgA	unknown	unknown	gnl\|CDD\|237039
NZ_CP011036.1\|WP_086993122.1\|566447_567449_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274092
NZ_CP011036.1\|WP_089367762.1\|587528_588398_-\|TIGR03899-family-protein	unknown	unknown	gnl\|CDD\|274842
NZ_CP011036.1\|WP_089367754.1\|568459_569986_+\|thiamine-phosphate-synthase	unknown	unknown	gnl\|CDD\|238574
NZ_CP011036.1\|WP_089367759.1\|583870_584551_+\|phage-shock-protein-PspA	unknown	unknown	gnl\|CDD\|274372
NZ_CP011036.1\|WP_089367755.1\|574486_574915_-\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|223509
NZ_CP011036.1\|WP_089367760.1\|585725_586712_+\|DUF2333-family-protein	unknown	unknown	gnl\|CDD\|378387
NZ_CP011036.1\|WP_058372577.1\|573005_573551_+\|oligoribonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235429
NZ_CP011036.1\|WP_089368929.1\|563581_563959_+\|META-domain-containing-protein	unknown	unknown	gnl\|CDD\|377111
NZ_CP011036.1\|WP_011327195.1\|570943_571771_-\|phosphatidylserine-decarboxylase	unknown	unknown	gnl\|CDD\|234591
NZ_CP011036.1\|WP_058372571.1\|564406_566359_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NZ_CP011036.1\|WP_011327191.1\|567456_567651_+\|sulfur-carrier-protein-ThiS	unknown	unknown	gnl\|CDD\|225015
NZ_CP011036.1\|WP_089367757.1\|575442_575880_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|183251
NZ_CP011036.1\|WP_089367761.1\|586715_587492_+\|TIGR04219-family-outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|275061
NZ_CP011036.1\|WP_089367756.1\|574911_575379_-\|chemotaxis-protein-CheX	unknown	unknown	gnl\|CDD\|381734
NZ_CP011036.1\|WP_089367758.1\|582648_583617_+\|tRNA-dihydrouridine(20/20a)-synthase-DusA	unknown	unknown	gnl\|CDD\|236991
NZ_CP011036.1\|WP_086996934.1\|585207_585717_+\|copper-chaperone-PCu(A)C	unknown	unknown	gnl\|CDD\|377298
NZ_CP011036.1\|WP_086996915.1\|584561_584768_+\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|132023
NZ_CP011036.1\|WP_089367753.1\|567656_568448_+\|thiazole-synthase	unknown	unknown	gnl\|CDD\|234687

Protein	Function_ID	Function_description	E-value
NZ_CP011036.1\|WP_086993126.1\|570008_570755_+\|HesA/MoeB/ThiF-family-protein	gnl\|CDD\|238386	cd00757, ThiF_MoeB_HesA_family, ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD and ThiS, respectively, on the alpha-phosphate of an ATP molecule bound at the active site of the activating enzymes, leading to the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD and ThiS. MoeB, as the MPT synthase (MoaE/MoaD complex) sulfurase, is involved in the biosynthesis of the molybdenum cofactor, a derivative of the tricyclic pterin, molybdopterin (MPT). ThiF catalyzes the adenylation of ThiS, as part of the biosynthesis pathway of thiamin pyrophosphate (vitamin B1). .	1.46735e-97
NZ_CP011036.1\|WP_011327196.1\|571825_572884_-\|small-ribosomal-subunit-biogenesis-GTPase-RsgA	gnl\|CDD\|237039	PRK12288, PRK12288, small ribosomal subunit biogenesis GTPase RsgA.	0
NZ_CP011036.1\|WP_086993122.1\|566447_567449_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	4.32493e-66
NZ_CP011036.1\|WP_089367762.1\|587528_588398_-\|TIGR03899-family-protein	gnl\|CDD\|274842	TIGR03899, hypothetical_protein, TIGR03899 family protein. Members of this protein family are conserved hypothetical proteins with a limited species distribution within the Gammaproteobacteria. It is common in the genera Vibrio and Shewanella, and in this resembles the C-terminal domain and putative protein sorting motif TIGR03501. This model, but design, does not extend to all homologs,but rather represents a particular clade.	3.57843e-121
NZ_CP011036.1\|WP_089367754.1\|568459_569986_+\|thiamine-phosphate-synthase	gnl\|CDD\|238574	cd01169, HMPP_kinase, 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of the hydroxyl group of HMP to form 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate (HMP-P) and then the phophorylation of HMP-P to form 4-amino-5-hydroxymethyl-2-methyl-pyrimidine pyrophosphate (HMP-PP), which is the substrate for the thiamine synthase coupling reaction.	5.78661e-98
NZ_CP011036.1\|WP_089367759.1\|583870_584551_+\|phage-shock-protein-PspA	gnl\|CDD\|274372	TIGR02977, phage_shock_protein_A, phage shock protein A. Members of this family are the phage shock protein PspA, from the phage shock operon. This is a narrower family than the set of PspA and its homologs, sometimes several in a genome, as described by pfam04012. PspA appears to maintain the protonmotive force under stress conditions that include overexpression of certain phage secretins, heat shock, ethanol, and protein export defects. [Cellular processes, Adaptations to atypical conditions].	4.70226e-59
NZ_CP011036.1\|WP_089367755.1\|574486_574915_-\|YjbQ-family-protein	gnl\|CDD\|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	4.10462e-56
NZ_CP011036.1\|WP_089367760.1\|585725_586712_+\|DUF2333-family-protein	gnl\|CDD\|378387	pfam10095, DUF2333, Uncharacterized protein conserved in bacteria (DUF2333). Members of this family of hypothetical bacterial proteins have no known function.	0
NZ_CP011036.1\|WP_058372577.1\|573005_573551_+\|oligoribonuclease	gnl\|CDD\|235429	PRK05359, PRK05359, oligoribonuclease; Provisional.	5.62671e-131
NZ_CP011036.1\|WP_089368929.1\|563581_563959_+\|META-domain-containing-protein	gnl\|CDD\|377111	pfam03724, META, META domain. Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.	2.8881e-26
NZ_CP011036.1\|WP_011327195.1\|570943_571771_-\|phosphatidylserine-decarboxylase	gnl\|CDD\|234591	PRK00044, psd, phosphatidylserine decarboxylase; Reviewed.	0
NZ_CP011036.1\|WP_058372571.1\|564406_566359_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NZ_CP011036.1\|WP_011327191.1\|567456_567651_+\|sulfur-carrier-protein-ThiS	gnl\|CDD\|225015	COG2104, ThiS, Sulfur transfer protein involved in thiamine biosynthesis [Coenzyme metabolism].	6.02487e-13
NZ_CP011036.1\|WP_089367757.1\|575442_575880_-\|transcriptional-repressor	gnl\|CDD\|183251	PRK11639, PRK11639, zinc uptake transcriptional repressor Zur.	2.41677e-50
NZ_CP011036.1\|WP_089367761.1\|586715_587492_+\|TIGR04219-family-outer-membrane-beta-barrel-protein	gnl\|CDD\|275061	TIGR04219, hypothetical_protein, outer membrane protein. Members of this protein family are outer membrane proteins (OMP), as can be seen by their homology to YfaZ protein (see ) and by the OMP targeting region at the C-terminus, including a C-terminal Phe residue. Members of this protein family are found in the great majority of genomes with the GlyGly-CTERM protein sorting signal and the rhombosortase putative sorting enzyme, although the relationship may be fortuitous.	3.98945e-94
NZ_CP011036.1\|WP_089367756.1\|574911_575379_-\|chemotaxis-protein-CheX	gnl\|CDD\|381734	cd17906, CheX, chemotaxis phosphatase CheX. This family contains CheX CheY-P phosphatase which is very closely related to CheC chemotaxis phosphatase; both dephosphorylate CheY, although CheC requires binding of CheD to achieve the level of activity of CheX. CheX has been shown to be the most powerful CheY-P phosphatase of the CheC-FliY-CheX (CXY) family. Structural and functional data of CheX and its CheY3 substrate in Borrelia burgdorferi (the causative agent of Lyme disease) bound to the phosphoryl analog BeF3(-) and Mg2+ reveal a unique mode of binding, but a catalytic mechanism which is virtually identical to that used by the structurally unrelated CheZ, providing a striking example of convergent evolution. Thus, CheX is quite divergent from the rest of the CXY family; it forms a dimer and some may function outside chemotaxis. The data also suggest a possible CheX regulatory mechanism through dissociation of the CheX homodimer.	6.01764e-54
NZ_CP011036.1\|WP_089367758.1\|582648_583617_+\|tRNA-dihydrouridine(20/20a)-synthase-DusA	gnl\|CDD\|236991	PRK11815, PRK11815, tRNA dihydrouridine(20/20a) synthase DusA.	0
NZ_CP011036.1\|WP_086996934.1\|585207_585717_+\|copper-chaperone-PCu(A)C	gnl\|CDD\|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	1.3913e-39
NZ_CP011036.1\|WP_086996915.1\|584561_584768_+\|PspC-domain-containing-protein	gnl\|CDD\|132023	TIGR02978, Phage_shock_protein_C., phage shock protein C. All members of this protein family are the phage shock protein PspC. These proteins contain a PspC domain, as do other members of the larger family of proteins described by pfam04024. The phage shock regulon is restricted to the Proteobacteria and somewhat sparsely distributed there. It is expressed, under positive control of a sigma-54-dependent transcription factor, PspF, which binds and is modulated by PspA. Stresses that induce the psp regulon include phage secretin overexpression, ethanol, heat shock, and protein export defects. [Cellular processes, Adaptations to atypical conditions].	5.52868e-12
NZ_CP011036.1\|WP_089367753.1\|567656_568448_+\|thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	1.81324e-153

>NZ_CP011036.1|WP_058372577.1|573005_573551_+|oligoribonuclease
MNINKSNLIWLDLEMTGLEPETDKILEIATVVTDADLNILAEGPTIAIHQSNELLDSMDEWCTTQHGKSGLTARCKASTYDEAYAVEQTIAFLKQWVPAGASPMCGNSIGQDRRFMNKYMRELEDFFHYRNLDVSTIKELARRWKPEVLAQVNKKGSHLALDDIKDSIMELKVYREKFFNL
>NZ_CP011036.1|WP_011327196.1|571825_572884_-|small-ribosomal-subunit-biogenesis-GTPase-RsgA
MAKQKKLSKGQSRQIKANHQKRISSADARPAKKGAQEWQTDNLGQVESAIVISRFGQHADVEVESGEVLRCNIRRTVSNLVCGDEVLFRRAKVSEGDLAGVIEATQERRSQLTRPDFYDGVKVIAANIDQILMVSAVLPEFTPSIIDRYLIACEDMGIEPILVLNKIDLIDAQGLSEIQKVLDVYRKLDYKVLLVSNISTDGIDELKDVLVGKNNIFVGQSGVGKSTLVNTVLPDAEILTKEVSENSGLGQHTTTVSRLHHLPSGGNLIDSPGIREFGLWHLEVDRVTWCFKEFREFIGGCRFRDCKHLNDPGCIIKEAVADGKISQLRFDSYHRILETMADGRAGSRAPRV
>NZ_CP011036.1|WP_011327195.1|570943_571771_-|phosphatidylserine-decarboxylase
MPKHFISRVVGKLAAAKAGVLTTTLIKLFIKQYKVDMSEAKHPDPAHYESFNEFFTRPLKDGARPIVADSDIIIHPVDGAISQLGDIVDGQLIQAKGHDYSLQALLGGNKDDTTPFLGGKFATIYLAPKDYHRIHMPIDGTLSKMIYVPGDLFSVNPLTAQNVPNLFARNERVVAIFETEIGPLAMVLVGATIVASIETIWAGTVTPPAGSDVFSWNYPTKGENAISLKKGEEMGRFKLGSTVVLAWGDDKADILDDQLPETVTRLGTPFAKIDD
>NZ_CP011036.1|WP_086993126.1|570008_570755_+|HesA/MoeB/ThiF-family-protein
MNELSDKEMLRYSRHILLKEVGLAGQLKLKSASVAVVGAGGLGSPALLYLAAAGIGKLILIDDDAVELSNLQRQVLYKVNHLGQKKVVAAGKVLASLNNQITIITHAEKLTQDNSAALLNNADIVLDCSDNFTTRYSVNRFCVQHKTPLISGAALATKGQLISLDLRNANSPCYGCIFPQSDIAPLINCDNAGVISPLLGIIGSMQAQLTLNMLLGHSSDCVFMSINALTLQQQQFKVVKDIDCKECR
>NZ_CP011036.1|WP_089367754.1|568459_569986_+|thiamine-phosphate-synthase
MNNVVWTIAGSDSGGGAGIQADIKAMQSFGVHGCTAITALTAQNSLGVEAINAVSTDIIESQLLALEKDMKAKVIKIGMLANVQQIQLISEHISHYKAKWPVSPVIVYDPVAIATSGDLLTEEDTVSAIKECLLPLVDVITPNTHETQLLTGVYLIGPAAIKEAANKLLSWGAKAVVIKGGHWDYPSGYCIDYCINNFTQKGEEYWLGNEKIQTPHNHGTGCSMASVIAACLAKDYPLKDAFILAKAYINQGLKVAVRYGEGIGPVAQTSFPTNLADYPQVIEAGSWLGDELDFDVPLDFNMAADFAPCESKSLGLYAVVDSVDWLEKCLQQGVKTAQLRVKNKDDAQLDELVAKAVALGEQYNAQVFINDYWQLAIKHGAYGVHLGQQDLENTNLAAIKNAGLRLGLSTHGFYEMLRAHNYRPSYLAFGAIYPTTTKDMTGQIQGLEKLFKFVPLMQSYPTVAIGGIDLKRASQVAKTGVGSVAVVRAISEADDYVQAISALQAAIN
>NZ_CP011036.1|WP_089367753.1|567656_568448_+|thiazole-synthase
MLNNDYLTIYGEQIKSRLLIGSALYPSPAVMNESIVASGAEIVTVSLRRQQSAAAGDDFWQLIKNTGLKILPNTAGCHSVKEAITLAKMCREVFATDWIKLELIGDDYNLQPDPFALLEATKILIDDGFKVLPYCTDDLVLCQRLNALGCEVLMPWGAPIGTGKGLLNSYNLKTIRERLPETTLIVDAGLGLPSHACQALELGYDAVLLNSAIAGAGCPITMSRAFKAAVEAGRFAYNAKAMPEKDVAAPSTPTMGMPFWHQE
>NZ_CP011036.1|WP_011327191.1|567456_567651_+|sulfur-carrier-protein-ThiS
MNITINGELIAISSNKLINCLQDFGGVAPFAVAINGEFIPQSQHSDYQLTEGDSIELLSPIQGG
>NZ_CP011036.1|WP_086993122.1|566447_567449_+|FAD-dependent-oxidoreductase
MFYNIAVVGFGLTGRLAALELSKQHRVTVFEADNEHTQNSAGKVAAAMLAPLAESVLCEADLALMGLDSIKRWPGVIDELDSEVFFQQQGTLVVAHQQDKGDLLSFAQRLKPLANYTGESVNSQQIEMLEPELANRFSQGLFLPCDGQIDNQAFYQASFTQLNKRKVKFVFNQRVTINDNKINNREFDYIIDCRGLGAKDDKPLRGVRGEVARLYAPEVSLTRPVRLMHPRYPIYIAPKPNNEYVIGATEIESQDTGPATVRSALELLSAAYTVHSGFAEARLLNIQTGLRPAFCDNRPQVTHVGRVISINGLYRHGYMLAPSLVANALLCIE
>NZ_CP011036.1|WP_058372571.1|564406_566359_+|phosphomethylpyrimidine-synthase-ThiC
MSNTAKKSSRRETRAAASEYIYNLTGQPFPNSHKVYVEGTQNNIRVGMREITLSDTYIGGSDENPVYEPNEPLRVYDTSGPYTDPNFELDVRQGLAKFREQWIESRGDTELLESVTSRFTQQRMADEGLDHLRFEHLPKIRRGKAGKNVTQMHYARQGIITPEMEYVAIRENMGRKKIHAELLAAQHKGESFGASIPDFITPEFVRDEIARGRAILPNNINHPETEPMIVGRNFLVKVNANIGNSSVSSSIEEEVEKMVWSTRWGADTVMDLSTGRYIHETREWVVRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEILKQYDICFSLGDGLRPGSIADANDEAQFSELRTLGELTKLAWKHDVQVFIEGPGHVPMHMIKANMDEQLKHCDEAPFYTLGPLTTDIAPGYDHITSGIGAAQIAWYGCAMLCYVTPKEHLGLPNKEDVKEGLITYKIAAHAADLAKGHPGAQERDNALSKARFEFRWHDQFNIGLDPERAREYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVREYAKDLEARGIDPANAADTITIKMIDVEAQMKAKSDEFKKTGSEIYHKAI
>NZ_CP011036.1|WP_089368929.1|563581_563959_+|META-domain-containing-protein
MLIIGLCVGCASTQTVTSEQLKHTQWQLSRIDGLAIPPSFNASVGFIEALQVNGFAGCNNFFGEGELDDSSLTVNKIGMTRKSCGQQLDKFEQQLLHALQQGAQLKMQDQQLVMQGEKTFVFIAK
>NZ_CP011036.1|WP_089367755.1|574486_574915_-|YjbQ-family-protein
MSWQQKVITLKPRIRGFHLIDNEILIQIPELTNYKVGLLHLFIQHTSASLTINENADPTVRMDMESHFNEFVPQCQPYYRHDYEGDDDMPAHIKTSILGCELSIPITNGYLALGTWQGVYLGEHRDSGGTRRIVATIQGELF
>NZ_CP011036.1|WP_089367756.1|574911_575379_-|chemotaxis-protein-CheX
MNVEFINPFLSSLINVLSTMAQTQLKPGKPRIKTDEKACGDVSGLIGMVGPQTRGSFSITFDEQLALTIMERMLGERPDSINEEVTDMVGEITNMVTGGAKNLLGQKGFDFNMATPIVVSGKDHTITHKSQGKKILMPFTCDAGNANIEVSFDKL
>NZ_CP011036.1|WP_089367757.1|575442_575880_-|transcriptional-repressor
MNIESLVSKAKQVCDNRGARFTPIREKVFRLLASAQGGVGAYDLLEQLKVTETGAKPATIYRALDFLAELGFIHKIESTNAFMLCHHFDHIHPVQLLICDTCGFVKELHSTVISHELNSLAAEGGFVVSAQTIEAHGRCESCRVA
>NZ_CP011036.1|WP_089367758.1|582648_583617_+|tRNA-dihydrouridine(20/20a)-synthase-DusA
MKPLDRRFSVAPMLDWTDRHCRTFHRKMTKHTVLYTEMITTGAILFGRGDYLHFNQHEGPVALQLGGSDPQALAQCAKLAGERGYDEINLNVGCPSDRVQNGRFGACLMGEPQLVADCVAAMKAEVNIPVTVKTRIGIDEQDSYEFLCALIEASHNVGCDDFIIHARKAWLKGLSPKENREVPPLDYPRVYKLKKDYPQLDLSLNGGVKTIEQSLEHLQHIDGVMIGREAYSNPFILNEVDEKIYGDIANTQSRHEVVRSMYSYIEDEMRLGANFWHVARHMLGIFQGQPGARGFRRHLSENGHGKQADLSVMDKALSFVPK
>NZ_CP011036.1|WP_089367759.1|583870_584551_+|phage-shock-protein-PspA
MGIFNRVTDIVQANIVSILDKAEDPEKLLNLMISEMQDALTECRITTAALLCEEKTLKRQIENKNNNLVYWQDKAELAIERGRDDLAKSALLEKQAISNTVVAKQLQLETLQQSITKMTADCQRLQQKIAEAKAKQTQLVQRHNIVAARGQINSQLQSEKVAHALSRFEKVEQRVEGIEAQVEAYELTDSENTIAAQIDALAKNEQVDAELARLKADLKTNLKQSA
>NZ_CP011036.1|WP_086996915.1|584561_584768_+|PspC-domain-containing-protein
MNSFNSKRGWYKDPLDKKISGVCSGLAQRLDLPVWSTRLVTILLFLSFPFAIALGYFIAHCCLEEKAI
>NZ_CP011036.1|WP_086996934.1|585207_585717_+|copper-chaperone-PCu(A)C
MIKQCISIVLVSVLSLFSSSSMAHSGHDHDADVAIIKVSNAQVREFLPATTSSVGYLSIINHSDTVATLTKATIDGLGRVEIHEHSHVDGMMKMQKVESLTINAHQQIDFKPGGYHLMIFEPQEPLKVGQQRKLTLYFSDGNRVFTNAQVVSLASQAEQSQASKQHTHH
>NZ_CP011036.1|WP_089367760.1|585725_586712_+|DUF2333-family-protein
MSQHKGKIVAALAILLIIFYAIAVYWNTEPARFNVVEKAKQQAQQRNEQFVIGYTTTSTLITVASTLLEKPGGYLSNDVLPPSIIMDDMPAWEYGALEMVRDLALSMRKDFSRSQSQSTEHEALKKAQPQFNISSEAWAWPSAEGEYQKGIDYLLVYRTQIANDHERDSQFYARADNLRSWLKEAEKRLGSLSQRLSASVGQDKVNTDLAGNTSNTQATFSPLQQQAKTPWLDIDDVFYESRGATWALLHFLQAVEYDFADVLEKKNARVSVQQIIRELEATQETVWSPMILNGNGFGYVANHSLVMANYISRANAALIELSELLTQG
>NZ_CP011036.1|WP_089367761.1|586715_587492_+|TIGR04219-family-outer-membrane-beta-barrel-protein
MKKYCLAAALSMACLAPAAQADTLLGLYVGVDGWKADNEGSFSYKGNALQDFNFDDETFVSYYAALEHPVPLVPNIKLRYTELELAGATELNSQFIFGDQSFEKGRNINTVSDLTHIDYTFYYEIFDNDLISIDLGINAKQFDGEISVEYIPQNNASDSKQSETVEFSGFVPLVYGRAEAGLPFTGLSVFFEGSFLAIDDSKVQDYQMGIAWEFIDNLAIDVAVKAGYRSMTLELDDVDDINTNIDASGPFAGIQVHF
>NZ_CP011036.1|WP_089367762.1|587528_588398_-|TIGR03899-family-protein
MAVKTAQARINLANTIESLLGYPIIKVGNNEQSYGPQGKVKPLYRINSDNTVLARAQKRQDLLLIKQQQNIETILAMAMDFCPDVASSKQPDADWVEHFVALCGDTSNQSMQSLWAKILTGETLNPGTFSIKSLQTLKHMTQREADSLQKCVPLSGYNEKDDSHFILLGFYKKPSLFDLLRKGNKVSLNLGKTGISFPDILTLMDLNLLYRKEIESAVLKTGQELTLSFLSQKVTLKAKNSDLVLSYYKFTQTGDELSKLINYPVNKVYKQLLNSALESEFELAWHTTK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011036_1	1.2\|440042\|24\|NZ_CP011036\|PILER-CR	440042-440065	24	MK424903	Pseudoalteromonas phage GXT1010, partial genome	298-321	2	0.917
NZ_CP011036_1	1.4\|440042\|31\|NZ_CP011036\|CRISPRCasFinder,CRT	440042-440072	31	MK424903	Pseudoalteromonas phage GXT1010, partial genome	298-328	2	0.935

1. spacer 1.2|440042|24|NZ_CP011036|PILER-CR matches to MK424903 (Pseudoalteromonas phage GXT1010, partial genome) position: , mismatch: 2, identity: 0.917

atatgcacggcaataatacagcgt	CRISPR spacer
acatgcacggcaacaatacagcgt	Protospacer
*.***********.**********

2. spacer 1.4|440042|31|NZ_CP011036|CRISPRCasFinder,CRT matches to MK424903 (Pseudoalteromonas phage GXT1010, partial genome) position: , mismatch: 2, identity: 0.935

atatgcacggcaataatacagcgtttgcaaa	CRISPR spacer
acatgcacggcaacaatacagcgtttgcaaa	Protospacer
*.***********.*****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

297619 : 351599

Streptococcus_phage(16.67%)

transposase,protease,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011326980.1\|297619_298096_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_041454319.1\|298148_299492_+	AMIN domain-containing protein	A0A067ZJB6	Vibrio_phage	2.8e-16	30.1
WP_089367624.1\|299529_301386_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.8e-61	42.5
WP_041454320.1\|301396_302314_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_011326984.1\|302395_302659_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_011326985.1\|302675_303965_+	GTPase HflX	NA	NA	NA	NA
WP_011326986.1\|304066_305236_+\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_011326987.1\|305241_306120_+\|protease	protease modulator HflC	NA	NA	NA	NA
WP_011326988.1\|306331_307645_+	adenylosuccinate synthase	A0A2R8FF47	Brazilian_cedratvirus	1.4e-68	37.9
WP_011326989.1\|307979_308618_+	sel1 repeat family protein	NA	NA	NA	NA
WP_058372400.1\|308698_310546_-	sodium:proton antiporter	NA	NA	NA	NA
WP_011326992.1\|311409_312516_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-46	35.0
WP_086994847.1\|312512_313760_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.2e-96	47.3
WP_011326994.1\|314245_314632_+	hypothetical protein	NA	NA	NA	NA
WP_011326995.1\|314633_315134_+\|tRNA	prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_089367625.1\|315100_316249_-	MFS transporter	NA	NA	NA	NA
WP_089367626.1\|316513_317053_+	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_011326998.1\|317228_317552_+	c-type cytochrome	NA	NA	NA	NA
WP_011326999.1\|317694_318462_+	class II aldolase/adducin family protein	NA	NA	NA	NA
WP_011327000.1\|318489_319665_+	mandelate racemase/muconate lactonizing enzyme family protein	Q6A202	Oenococcus_phage	5.5e-56	35.3
WP_011327001.1\|319735_320119_-	hypothetical protein	NA	NA	NA	NA
WP_089367627.1\|320122_321688_-	peptidase	NA	NA	NA	NA
WP_089367628.1\|321737_322577_-	amidohydrolase family protein	NA	NA	NA	NA
WP_089367629.1\|322573_323302_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_011327005.1\|323333_323828_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_011327006.1\|323898_325368_-	transglycosylase SLT domain-containing protein	A0A1P8CWQ1	Bacillus_phage	2.2e-06	35.2
WP_089367630.1\|325424_326441_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_011327008.1\|326500_326806_-	cell division protein ZapA	NA	NA	NA	NA
WP_011327009.1\|326805_327036_-	hypothetical protein	NA	NA	NA	NA
WP_089367631.1\|327274_328114_+	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_089367632.1\|328170_328980_-	META domain-containing protein	NA	NA	NA	NA
WP_011327013.1\|329127_329694_-	hypothetical protein	NA	NA	NA	NA
WP_089367633.1\|330272_331499_-\|transposase	transposase	A0A077SL42	Escherichia_phage	6.8e-33	33.5
WP_089367634.1\|331537_331933_+\|transposase	IS200/IS605 family transposase	A0A1S5RG71	Helicobacter_phage	1.9e-21	41.7
WP_089367635.1\|332931_333303_+	hypothetical protein	NA	NA	NA	NA
WP_089367636.1\|333394_334720_+	TolC family protein	NA	NA	NA	NA
WP_089367637.1\|334709_336458_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_089367638.1\|336466_339583_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_011327019.1\|339724_340180_+	hypothetical protein	NA	NA	NA	NA
WP_011327021.1\|340446_340953_-	glycine cleavage system protein R	NA	NA	NA	NA
WP_089367639.1\|341310_343545_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_089367640.1\|343559_345209_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_011327024.1\|345231_346059_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-22	32.3
WP_011327025.1\|346101_346803_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_089367641.1\|346951_347629_+	TIGR00153 family protein	NA	NA	NA	NA
WP_041454322.1\|347668_348937_+	inorganic phosphate transporter	E5ESL8	Bathycoccus_sp._RCC1105_virus	2.7e-61	34.5
WP_089367642.1\|349112_350216_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q9G0F2	Phage_Gifsy-1	2.3e-136	64.9
WP_089367643.1\|350372_351599_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

355757 : 430888

uncultured_Mediterranean_phage(15.0%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011327031.1\|355757_356789_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_089367646.1\|356939_358067_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.9e-94	48.2
WP_011327033.1\|358093_358429_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.0e-11	40.9
WP_011327034.1\|358448_360308_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_089367647.1\|360317_361265_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	4.9e-39	36.6
WP_011327036.1\|361543_362347_-	inositol-1-monophosphatase	NA	NA	NA	NA
WP_011327037.1\|362617_363283_-	DUF1707 and DUF2154 domain-containing protein	NA	NA	NA	NA
WP_011327038.1\|363597_364161_+	BON domain-containing protein	NA	NA	NA	NA
WP_011327039.1\|364236_364395_+	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_089367648.1\|365230_366004_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	5.3e-92	66.0
WP_089367649.1\|366000_367035_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	7.1e-100	52.6
WP_089367650.1\|367077_367797_+	zeta toxin family protein	NA	NA	NA	NA
WP_011327041.1\|367805_367973_+	hypothetical protein	NA	NA	NA	NA
WP_058372437.1\|368120_368450_-	5-carboxymethyl-2-hydroxymuconate Delta-isomerase	NA	NA	NA	NA
WP_089367651.1\|368605_370732_-	translocation protein TolB	NA	NA	NA	NA
WP_089367652.1\|371063_374084_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	1.5e-17	35.3
WP_013465976.1\|374269_374740_+	CreA family protein	A0A2I7SAK3	Vibrio_phage	1.3e-16	34.2
WP_089367653.1\|374743_375517_+	hypothetical protein	NA	NA	NA	NA
WP_089367654.1\|375530_376157_+	LysE family translocator	NA	NA	NA	NA
WP_011327047.1\|376191_376686_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_086995902.1\|376707_378249_+	serine hydrolase	NA	NA	NA	NA
WP_011327049.1\|378365_379286_+	histone deacetylase family protein	A0A2K9L4C2	Tupanvirus	5.7e-16	30.7
WP_041454323.1\|379268_379565_-	hypothetical protein	NA	NA	NA	NA
WP_089367655.1\|379641_382170_+	EAL domain-containing protein	NA	NA	NA	NA
WP_011327052.1\|382166_382976_-	DUF2797 domain-containing protein	NA	NA	NA	NA
WP_011327055.1\|384739_386029_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_089367656.1\|386045_386870_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_086996647.1\|386973_388560_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG3	Prochlorococcus_phage	1.6e-47	53.9
WP_011327058.1\|389033_389324_-	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_086996644.1\|389343_390324_-\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_089367657.1\|390595_391477_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_011327061.1\|391558_393406_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	9.3e-34	32.4
WP_011327062.1\|393531_395283_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.3e-64	36.5
WP_041454325.1\|395508_395955_-	GatB/YqeY domain-containing protein	G3MAQ0	Bacillus_virus	1.4e-07	31.0
WP_002957797.1\|395974_396190_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_011327064.1\|396335_396941_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_089367658.1\|397148_399314_+	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_058372450.1\|399548_400226_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	3.5e-31	37.9
WP_011327067.1\|400222_401209_+	cell division protein FtsX	NA	NA	NA	NA
WP_011327068.1\|401433_402297_+	RNA polymerase sigma factor RpoH	A0A248SJA5	Salicola_phage	9.6e-42	39.0
WP_089367659.1\|403024_403852_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_036932744.1\|404161_404575_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.7e-25	42.2
WP_050582221.1\|404632_405814_+\|transposase	transposase	A0A068A1P5	Thermus_phage	2.0e-37	36.0
WP_011327071.1\|406655_408017_-	glutathione-disulfide reductase	NA	NA	NA	NA
WP_089368924.1\|408222_410274_+	oligopeptidase A	A0A1V0SD92	Indivirus	2.4e-43	23.4
WP_089367660.1\|410482_411241_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_089367661.1\|411482_412112_+	hypothetical protein	NA	NA	NA	NA
WP_089367662.1\|413371_414917_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.9e-11	27.7
WP_089367663.1\|415587_416589_+	AAA family ATPase	NA	NA	NA	NA
WP_089367664.1\|416729_417605_-	hypothetical protein	NA	NA	NA	NA
WP_089367665.1\|417695_419453_-	hypothetical protein	NA	NA	NA	NA
WP_024600838.1\|419622_421167_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	5.6e-125	45.9
WP_024603886.1\|421181_421937_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	9.2e-57	49.6
WP_089367666.1\|422002_424762_-	ATP-binding protein	NA	NA	NA	NA
WP_089367667.1\|424867_425107_-	hypothetical protein	NA	NA	NA	NA
WP_089367668.1\|425119_430888_-\|protease	trypsin-like serine protease	NA	NA	NA	NA

DBSCAN-SWA_3

453943 : 520643

Bacillus_phage(18.18%)

transposase,tRNA,integrase

attL 489632:489649|attR 521144:521161

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011327082.1\|453943_454408_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_083497533.1\|454568_455435_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_089367687.1\|455785_456718_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_089367688.1\|456721_458137_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_089367689.1\|458114_458804_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.1e-35	36.5
WP_086996570.1\|458968_459454_+	hypothetical protein	NA	NA	NA	NA
WP_011327088.1\|459995_460226_-	DNA gyrase inhibitor YacG	NA	NA	NA	NA
WP_089367690.1\|460898_462572_-	type IV-A pilus assembly ATPase PilB	NA	NA	NA	NA
WP_089367691.1\|462692_463325_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_089367692.1\|463326_464247_-	prepilin peptidase	NA	NA	NA	NA
WP_089367693.1\|464704_465088_-	GxxExxY protein	NA	NA	NA	NA
WP_089367694.1\|465748_466966_-	type II secretion system F family protein	NA	NA	NA	NA
WP_089367695.1\|466976_467417_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_089368925.1\|467437_467854_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_089367696.1\|468327_469173_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_089367662.1\|469399_470946_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.9e-11	27.7
WP_089367697.1\|471525_472080_+	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	A0A1W6DX33	Sphingobium_phage	1.1e-09	33.3
WP_089367698.1\|472093_472945_+	beta-lactamase regulator AmpE	NA	NA	NA	NA
WP_089367699.1\|473203_473656_-\|transposase	transposase	NA	NA	NA	NA
WP_011327101.1\|474231_474981_+	pyruvate dehydrogenase complex transcriptional repressor PdhR	NA	NA	NA	NA
WP_089367700.1\|475064_477731_+	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_089367701.1\|477741_479694_+	pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_089367702.1\|479851_481279_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.1e-46	29.2
WP_041454330.1\|481567_482242_+	DTW domain-containing protein	NA	NA	NA	NA
WP_011327107.1\|484779_485598_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_089367703.1\|485630_486413_+	DUF481 domain-containing protein	NA	NA	NA	NA
WP_089367704.1\|486535_489088_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_089367705.1\|489340_490303_+	LPS O-antigen length regulator	NA	NA	NA	NA
489632:489649	attL	NA	NA	NA	NA
WP_089367706.1\|490687_492127_+	flippase	NA	NA	NA	NA
WP_089367707.1\|492123_493470_+	hypothetical protein	NA	NA	NA	NA
WP_089367708.1\|493466_494597_+	hypothetical protein	NA	NA	NA	NA
WP_089367709.1\|494578_495553_+	hypothetical protein	NA	NA	NA	NA
WP_089367710.1\|495552_496581_+	glycosyltransferase	NA	NA	NA	NA
WP_089367711.1\|496589_497387_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	5.0e-45	41.1
WP_089368926.1\|497452_497956_+	HAD hydrolase family protein	E3T535	Cafeteria_roenbergensis_virus	4.8e-17	37.9
WP_089368927.1\|497962_498706_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_089367712.1\|498707_499637_+	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	1.0e-41	36.8
WP_089367713.1\|499660_500698_+	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	2.8e-40	35.0
WP_089367714.1\|500697_501807_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_089367715.1\|501846_502977_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SJE0	Klosneuvirus	8.3e-102	48.1
WP_089367716.1\|502976_504179_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_089367717.1\|504178_504580_+	WbuC family cupin fold metalloprotein	NA	NA	NA	NA
WP_089367718.1\|504726_505803_+	UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase	NA	NA	NA	NA
WP_089367719.1\|505961_507317_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_089367720.1\|507768_509445_-	hypothetical protein	NA	NA	NA	NA
WP_089368928.1\|509575_510730_-\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	2.4e-27	26.3
WP_089367722.1\|511078_512320_-	hypothetical protein	NA	NA	NA	NA
WP_089367723.1\|512329_515215_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_089367724.1\|515207_516812_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_008464267.1\|516966_517446_-	hypothetical protein	NA	NA	NA	NA
WP_050582221.1\|519461_520643_-\|transposase	transposase	A0A068A1P5	Thermus_phage	2.0e-37	36.0
521144:521161	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1090416 : 1101183

Agrobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089367958.1\|1090416_1092267_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	9.5e-55	34.0
WP_011327680.1\|1092427_1092691_-	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	6.7e-23	61.5
WP_089367959.1\|1093040_1093487_+	Hsp20 family protein	A0A2L0V0Y9	Agrobacterium_phage	5.5e-17	42.0
WP_011327682.1\|1093777_1094224_+	Hsp20 family protein	A0A2L0V0Y9	Agrobacterium_phage	2.9e-18	42.9
WP_089367960.1\|1094303_1095857_-	cryptochrome/photolyase family protein	A0A1V0SE91	Indivirus	1.8e-46	29.2
WP_041454374.1\|1096503_1096959_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_089367961.1\|1096997_1098497_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_011327686.1\|1098522_1101183_+	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	1.5e-21	24.6

DBSCAN-SWA_5

1343054 : 1397004

uncultured_Mediterranean_phage(59.09%)

portal,capsid,terminase,integrase

attL 1342826:1342841|attR 1398228:1398243

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1342826:1342841	attL	NA	NA	NA	NA
WP_089368033.1\|1343054_1344254_+\|integrase	integrase family protein	K7P703	Enterobacteria_phage	3.3e-48	30.4
WP_089368034.1\|1344234_1344438_-	DNA-binding protein	NA	NA	NA	NA
WP_089368035.1\|1344434_1344716_-	hypothetical protein	NA	NA	NA	NA
WP_089368036.1\|1344723_1345140_-	hypothetical protein	NA	NA	NA	NA
WP_089368037.1\|1345142_1345514_-	hypothetical protein	NA	NA	NA	NA
WP_089368038.1\|1345513_1345705_-	hypothetical protein	A0A1L5C294	Pseudoalteromonas_phage	4.7e-10	43.8
WP_089368039.1\|1345706_1346153_-	hypothetical protein	NA	NA	NA	NA
WP_089368040.1\|1346149_1346779_-	hypothetical protein	A0A2I7RGA2	Vibrio_phage	1.1e-63	60.6
WP_115121828.1\|1346789_1347506_-	single-stranded DNA-binding protein	S5M9Z7	Pseudoalteromonas_phage	5.7e-48	74.8
WP_089368042.1\|1347526_1348681_-	recombination-associated protein RdgC	A0A2I7RNT5	Vibrio_phage	3.3e-61	42.2
WP_089368043.1\|1348832_1349072_-	DUF1317 family protein	NA	NA	NA	NA
WP_089368044.1\|1349128_1350334_-	hypothetical protein	NA	NA	NA	NA
WP_089368045.1\|1350338_1351277_-	hypothetical protein	A0A191ZDG3	Pseudoalteromonas_virus	2.5e-59	41.1
WP_089368046.1\|1351281_1351578_-	hypothetical protein	NA	NA	NA	NA
WP_089368047.1\|1351732_1352035_-	hypothetical protein	NA	NA	NA	NA
WP_089368048.1\|1352052_1352244_-	hypothetical protein	NA	NA	NA	NA
WP_089368049.1\|1352404_1352755_-	hypothetical protein	NA	NA	NA	NA
WP_089368050.1\|1353075_1353381_-	hypothetical protein	NA	NA	NA	NA
WP_089368051.1\|1353393_1354008_-	helix-turn-helix domain-containing protein	K7PLZ5	Enterobacterial_phage	1.3e-40	44.9
WP_157696002.1\|1354154_1354367_+	Cro/Cl family transcriptional regulator	NA	NA	NA	NA
WP_089368053.1\|1354379_1354904_+	hypothetical protein	Q3HQZ3	Burkholderia_phage	6.5e-09	29.1
WP_089368054.1\|1354903_1355119_+	hypothetical protein	NA	NA	NA	NA
WP_089368055.1\|1355131_1355461_-	hypothetical protein	NA	NA	NA	NA
WP_089368056.1\|1355557_1355773_+	hypothetical protein	NA	NA	NA	NA
WP_089368057.1\|1355832_1356741_+	replication protein	A0A2I7RT63	Vibrio_phage	8.3e-20	47.5
WP_089368058.1\|1356740_1357319_+	hypothetical protein	A0A1B1ITJ7	uncultured_Mediterranean_phage	8.3e-74	69.3
WP_089368059.1\|1357315_1357729_+	hypothetical protein	A0A1B1ITL3	uncultured_Mediterranean_phage	7.8e-34	58.3
WP_089368060.1\|1357738_1358053_+	hypothetical protein	A0A1B1ITH3	uncultured_Mediterranean_phage	1.7e-12	44.0
WP_089368061.1\|1358052_1358505_+	hypothetical protein	A0A1B1ITH8	uncultured_Mediterranean_phage	2.4e-68	85.3
WP_089368062.1\|1358491_1358794_+	DUF1364 domain-containing protein	A0A1B1ITP8	uncultured_Mediterranean_phage	1.8e-43	83.7
WP_089368063.1\|1358790_1359165_+	RusA family crossover junction endodeoxyribonuclease	K7PM48	Enterobacteria_phage	9.3e-18	39.5
WP_089368064.1\|1359166_1359727_+	hypothetical protein	A0A1B1ITI3	uncultured_Mediterranean_phage	3.9e-84	78.5
WP_089368065.1\|1359879_1360632_+	hypothetical protein	NA	NA	NA	NA
WP_089368066.1\|1360648_1361050_+	hypothetical protein	NA	NA	NA	NA
WP_089368067.1\|1361318_1361525_-	hypothetical protein	NA	NA	NA	NA
WP_089368068.1\|1362040_1362226_+	hypothetical protein	A0A1B1ITJ6	uncultured_Mediterranean_phage	4.6e-18	70.0
WP_089368069.1\|1362222_1362963_+	hypothetical protein	NA	NA	NA	NA
WP_089368070.1\|1362972_1363353_+	S24 family peptidase	A0A1B1ITQ0	uncultured_Mediterranean_phage	1.3e-51	80.2
WP_089368071.1\|1363354_1364059_+	hypothetical protein	NA	NA	NA	NA
WP_089368072.1\|1364235_1364661_+	hypothetical protein	M4M9N1	Vibrio_phage	4.7e-34	52.1
WP_089368073.1\|1364657_1365149_+	hypothetical protein	A0A2I7R2B5	Vibrio_phage	1.5e-39	51.4
WP_089368074.1\|1365148_1365490_+	hypothetical protein	I3PUY0	Vibrio_phage	1.5e-35	64.4
WP_089368075.1\|1365489_1366203_+	hypothetical protein	A0A2L1IV66	Escherichia_phage	2.7e-13	30.8
WP_089368946.1\|1366325_1367936_+\|terminase	terminase	A0A1B1ITK1	uncultured_Mediterranean_phage	1.8e-288	88.4
WP_089368076.1\|1367939_1370036_+\|portal	portal protein	A0A1B1ITH6	uncultured_Mediterranean_phage	1.8e-304	78.4
WP_089368077.1\|1370038_1370428_+	hypothetical protein	A0A1B1ITG4	uncultured_Mediterranean_phage	1.5e-26	50.4
WP_089368078.1\|1370433_1370634_+	hypothetical protein	A0A2I7RUV9	Vibrio_phage	6.7e-15	65.6
WP_089368079.1\|1370701_1371793_+	hypothetical protein	A0A2L1IV47	Escherichia_phage	7.4e-23	30.2
WP_089368080.1\|1371802_1373014_+\|capsid	N4-gp56 family major capsid protein	A0A1B1ITP0	uncultured_Mediterranean_phage	6.6e-206	87.3
WP_089368081.1\|1373067_1373448_+	hypothetical protein	A0A1B1ITH7	uncultured_Mediterranean_phage	4.1e-37	60.3
WP_089368082.1\|1373512_1373962_+	hypothetical protein	A0A1B1ITJ2	uncultured_Mediterranean_phage	4.7e-40	62.1
WP_089368083.1\|1373965_1374526_+	hypothetical protein	A0A1B1ITE9	uncultured_Mediterranean_phage	1.9e-54	53.5
WP_089368084.1\|1374525_1375179_+	hypothetical protein	A0A1B1ITG1	uncultured_Mediterranean_phage	1.3e-94	76.4
WP_089368085.1\|1375180_1378078_+	hypothetical protein	A0A1B1ITM8	uncultured_Mediterranean_phage	1.5e-256	51.1
WP_089368086.1\|1378067_1378706_+	hypothetical protein	A0A1B1ITJ0	uncultured_Mediterranean_phage	1.5e-55	54.0
WP_089368087.1\|1378717_1379044_+	hypothetical protein	A0A1B1ITG3	uncultured_Mediterranean_phage	4.3e-43	77.6
WP_089368088.1\|1379094_1380705_+	hypothetical protein	A0A1B1ITF2	uncultured_Mediterranean_phage	3.3e-261	78.9
WP_089368089.1\|1380705_1384362_+	DUF1983 domain-containing protein	A0A1B1ITH4	uncultured_Mediterranean_phage	2.6e-80	46.1
WP_089368090.1\|1384400_1384826_+	hypothetical protein	A0A1B1ITG7	uncultured_Mediterranean_phage	8.9e-57	71.7
WP_089368091.1\|1384818_1385454_+	hypothetical protein	A0A1B1ITI4	uncultured_Mediterranean_phage	1.6e-62	63.3
WP_089368092.1\|1385455_1385926_+	hypothetical protein	A0A1B1ITE3	uncultured_Mediterranean_phage	2.2e-32	54.8
WP_089368093.1\|1385925_1386183_+	hypothetical protein	A0A1B1ITE8	uncultured_Mediterranean_phage	1.3e-07	63.3
WP_089368094.1\|1386193_1387507_+	hypothetical protein	A0A1B1ITL8	uncultured_Mediterranean_phage	9.7e-78	43.9
WP_089368095.1\|1387496_1393706_+	hypothetical protein	A0A1I9KFG8	Aeromonas_phage	1.5e-197	38.5
WP_089368096.1\|1393737_1394298_-	hypothetical protein	NA	NA	NA	NA
WP_147207647.1\|1394334_1394706_-	DUF4156 domain-containing protein	NA	NA	NA	NA
WP_089368098.1\|1394687_1395452_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_157696003.1\|1395583_1395751_+	hypothetical protein	NA	NA	NA	NA
WP_157696004.1\|1395752_1395911_+	hypothetical protein	NA	NA	NA	NA
WP_089368099.1\|1395985_1396258_+	hypothetical protein	NA	NA	NA	NA
WP_115121826.1\|1396254_1397004_+	phage regulatory protein/antirepressor Ant	A0A0K0N5U2	Gordonia_phage	3.0e-31	38.2
1398228:1398243	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1452323 : 1483537

Pseudoalteromonas_phage(80.56%)

portal,capsid,terminase,head,tail,integrase

attL 1452136:1452158|attR 1484375:1484397

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1452136:1452158	attL	NA	NA	NA	NA
WP_089368118.1\|1452323_1453550_+\|integrase	site-specific integrase	K7P7J2	Enterobacteria_phage	1.5e-64	36.7
WP_089368119.1\|1453618_1455121_+	WYL domain-containing protein	A0A1L5C282	Pseudoalteromonas_phage	6.2e-20	61.4
WP_089368120.1\|1455170_1455809_-	helix-turn-helix domain-containing protein	U5P0T5	Shigella_phage	5.4e-34	52.8
WP_089368121.1\|1455959_1456178_+	transcriptional regulator	NA	NA	NA	NA
WP_058373173.1\|1456174_1456468_+	hypothetical protein	NA	NA	NA	NA
WP_089368122.1\|1456478_1456751_+	hypothetical protein	A0A1L5C2B4	Pseudoalteromonas_phage	1.3e-16	54.4
WP_089368123.1\|1456753_1457140_+	hypothetical protein	A0A1L5C285	Pseudoalteromonas_phage	2.4e-24	48.3
WP_089368124.1\|1457142_1457733_+	SAM-dependent methyltransferase	A0A1L5C2A0	Pseudoalteromonas_phage	6.3e-61	59.5
WP_089368125.1\|1457766_1458045_+	hypothetical protein	A0A1L5C2B9	Pseudoalteromonas_phage	8.7e-21	53.8
WP_089368126.1\|1458047_1461182_+	replication endonuclease	A0A1L5C2A7	Pseudoalteromonas_phage	0.0e+00	81.0
WP_089368127.1\|1461190_1461475_+	hypothetical protein	A0A1L5C294	Pseudoalteromonas_phage	2.3e-40	89.4
WP_089368128.1\|1461916_1462264_+	hypothetical protein	A0A2I7RHM8	Vibrio_phage	3.5e-19	55.8
WP_089368129.1\|1462446_1463130_+	DNA adenine methylase	A0A0M4S5U3	Salmonella_phage	8.4e-49	46.0
WP_089368130.1\|1463178_1463424_-	ogr/Delta-like zinc finger family protein	A0A1L5C2B5	Pseudoalteromonas_phage	4.2e-35	88.9
WP_089368131.1\|1463566_1463839_+	hypothetical protein	NA	NA	NA	NA
WP_089368132.1\|1463821_1464862_-\|portal	phage portal protein	A0A1L5C2C1	Pseudoalteromonas_phage	2.9e-178	93.4
WP_089368133.1\|1464843_1466628_-\|terminase	terminase	A0A1L5C295	Pseudoalteromonas_phage	0.0e+00	93.9
WP_089368134.1\|1466822_1467746_+	hypothetical protein	A0A1L5C292	Pseudoalteromonas_phage	5.9e-98	70.3
WP_089368135.1\|1467800_1468829_+\|capsid	phage major capsid protein, P2 family	A0A1L5C2B0	Pseudoalteromonas_phage	5.5e-153	79.7
WP_089368136.1\|1468897_1469425_+	hypothetical protein	A0A1L5C2C8	Pseudoalteromonas_phage	2.0e-26	77.0
WP_089368137.1\|1469472_1470084_+	hypothetical protein	A0A1L5C2B7	Pseudoalteromonas_phage	1.0e-90	88.6
WP_089368138.1\|1470195_1470645_+\|head	head completion/stabilization protein	A0A1L5C2A5	Pseudoalteromonas_phage	4.5e-67	87.2
WP_089368139.1\|1470641_1471124_+	hypothetical protein	A0A1L5C2C9	Pseudoalteromonas_phage	1.4e-79	92.5
WP_089368140.1\|1471120_1471777_+	hypothetical protein	A0A1L5C2C4	Pseudoalteromonas_phage	7.7e-92	82.1
WP_089368141.1\|1471781_1472888_+	DUF2586 family protein	A0A1L5C2B3	Pseudoalteromonas_phage	1.3e-179	86.7
WP_089368142.1\|1472899_1473349_+	DUF2597 family protein	A0A1L5C2D0	Pseudoalteromonas_phage	5.1e-71	92.6
WP_089368143.1\|1473364_1473565_+	hypothetical protein	A0A1L5C2A6	Pseudoalteromonas_phage	1.2e-24	80.3
WP_089368144.1\|1473569_1474121_+	hypothetical protein	A0A1L5C2A4	Pseudoalteromonas_phage	1.4e-86	86.2
WP_089368145.1\|1474123_1474513_+	hypothetical protein	A0A1B1ITB4	uncultured_Mediterranean_phage	5.5e-21	45.8
WP_089368146.1\|1474509_1474764_+	hypothetical protein	A0A1L5C2D5	Pseudoalteromonas_phage	3.6e-21	65.4
WP_089368147.1\|1474766_1475030_+	hypothetical protein	A5X9I7	Aeromonas_virus	9.4e-17	47.7
WP_167376931.1\|1475071_1475218_+	hypothetical protein	NA	NA	NA	NA
WP_089368148.1\|1475218_1476979_+\|tail	phage tail tape measure protein	A0A1L5C2B2	Pseudoalteromonas_phage	3.9e-231	74.9
WP_089368149.1\|1476975_1477311_+	DUF2590 family protein	A0A1L5C2D6	Pseudoalteromonas_phage	8.5e-47	82.9
WP_089368150.1\|1477310_1478507_+	hypothetical protein	A0A1L5C2D1	Pseudoalteromonas_phage	1.2e-178	78.3
WP_089368151.1\|1478503_1479136_+	hypothetical protein	A0A1L5C2C5	Pseudoalteromonas_phage	6.8e-61	67.7
WP_089368152.1\|1479154_1481608_+\|tail	phage tail protein	A0A1L5C2D7	Pseudoalteromonas_phage	1.2e-89	59.6
WP_089368949.1\|1481610_1482102_+	adenine glycosylase	A0A1L5C2B6	Pseudoalteromonas_phage	5.8e-60	80.2
WP_089368153.1\|1482101_1482791_+	hypothetical protein	A0A2I7RNK1	Vibrio_phage	6.6e-70	50.7
WP_089368154.1\|1482793_1483537_+	hypothetical protein	A0A1L5C2B1	Pseudoalteromonas_phage	2.4e-113	81.0
1484375:1484397	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1768248 : 1775531

Vibrio_phage(42.86%)

capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089368277.1\|1768248_1769391_-\|capsid	minor capsid protein	B5TA65	Burkholderia_phage	1.4e-48	40.1
WP_089368278.1\|1769392_1769935_-	hypothetical protein	D4HTZ6	Vibrio_phage	2.1e-42	50.0
WP_089368279.1\|1769922_1770381_-	hypothetical protein	M4MHH2	Vibrio_phage	7.1e-28	50.4
WP_011328186.1\|1770391_1771006_-	DUF3164 family protein	A0A2D1GNM4	Pseudomonas_phage	9.9e-41	42.3
WP_089368280.1\|1770998_1772501_-	DUF935 family protein	B5TA67	Burkholderia_phage	4.4e-58	34.8
WP_089368281.1\|1772493_1774233_-	hypothetical protein	A0A2D1GNP7	Pseudomonas_phage	7.3e-166	53.1
WP_011328189.1\|1774232_1774739_-	DUF1804 family protein	NA	NA	NA	NA
WP_089368282.1\|1774738_1775077_-	hypothetical protein	NA	NA	NA	NA
WP_011328191.1\|1775087_1775531_-	hypothetical protein	Q6WHL2	Vibrio_phage	3.3e-22	48.1

DBSCAN-SWA_8

1786981 : 1793157

Pseudomonas_virus(33.33%)

capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089368298.1\|1786981_1787449_-	hypothetical protein	L7THB5	Pseudomonas_virus	3.3e-20	33.1
WP_089368299.1\|1787451_1787814_-	helix-turn-helix transcriptional regulator	L7TKV7	Pseudomonas_virus	4.8e-19	46.6
WP_089368300.1\|1788051_1789218_+	hypothetical protein	B5TA92	Burkholderia_phage	3.4e-34	31.8
WP_089368301.1\|1789222_1789618_+	DUF2190 family protein	NA	NA	NA	NA
WP_089368302.1\|1789659_1790595_+\|capsid	capsid protein	Q5ZQX7	Pseudomonas_phage	1.6e-66	44.7
WP_089368303.1\|1790681_1791149_+	hypothetical protein	NA	NA	NA	NA
WP_089368304.1\|1791150_1791573_+	phage virion morphogenesis protein	B5TA98	Burkholderia_phage	7.5e-08	35.8
WP_011328223.1\|1791617_1792061_+	hypothetical protein	NA	NA	NA	NA
WP_011328224.1\|1792057_1792261_+	hypothetical protein	NA	NA	NA	NA
WP_089368305.1\|1792257_1793157_+	hypothetical protein	G8CLB2	Synechococcus_phage	6.5e-17	27.4

DBSCAN-SWA_9

1987974 : 2044226

Leptospira_phage(38.46%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011328398.1\|1987974_1988691_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_041454455.1\|1988683_1989388_+	arginyltransferase	NA	NA	NA	NA
WP_002962494.1\|1989478_1989697_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_089368371.1\|1989907_1992169_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.2e-160	41.2
WP_083497543.1\|1992237_1992546_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.7e-12	33.6
WP_011328402.1\|1992755_1992974_+	cold shock domain-containing protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	5.6e-15	57.4
WP_089368372.1\|1993770_1995993_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_089368373.1\|1996147_1997389_-	amidohydrolase family protein	NA	NA	NA	NA
WP_011328405.1\|1997401_1998784_-	amidohydrolase	NA	NA	NA	NA
WP_011328406.1\|1998884_1999670_-	hypothetical protein	NA	NA	NA	NA
WP_089368374.1\|1999912_2000275_+	DUF3718 domain-containing protein	NA	NA	NA	NA
WP_089368375.1\|2000343_2001036_-	DUF445 domain-containing protein	NA	NA	NA	NA
WP_011328408.1\|2001145_2002006_+	phosphotransferase	NA	NA	NA	NA
WP_011328409.1\|2002141_2002345_+	CPXCG motif-containing cysteine-rich protein	NA	NA	NA	NA
WP_089368376.1\|2002341_2002968_-	riboflavin synthase subunit alpha	A0A2I2L4R9	Orpheovirus	9.8e-20	35.4
WP_011328411.1\|2003139_2004495_+	MATE family efflux transporter	NA	NA	NA	NA
WP_089368377.1\|2004472_2005525_+	DUF3080 domain-containing protein	NA	NA	NA	NA
WP_125825535.1\|2006431_2006635_-	hypothetical protein	NA	NA	NA	NA
WP_008464634.1\|2007463_2008870_-	two-component sensor histidine kinase	NA	NA	NA	NA
WP_058429029.1\|2008869_2009544_-	response regulator transcription factor	W8CYM9	Bacillus_phage	8.9e-19	29.8
WP_076920374.1\|2009716_2011672_+	LTA synthase family protein	NA	NA	NA	NA
WP_024599462.1\|2011674_2013303_+	phosphoethanolamine--lipid A transferase	NA	NA	NA	NA
WP_024599461.1\|2013315_2013702_+	diacylglycerol kinase	NA	NA	NA	NA
WP_024599460.1\|2013812_2014388_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_024599458.1\|2015487_2015859_+	hypothetical protein	NA	NA	NA	NA
WP_013463096.1\|2015979_2016654_+	hypothetical protein	NA	NA	NA	NA
WP_089368378.1\|2016861_2017386_-	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
WP_008467385.1\|2017509_2017851_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_010554756.1\|2017847_2018198_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.6e-19	44.9
WP_002963282.1\|2018278_2019760_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	1.9e-61	35.1
WP_008467353.1\|2020021_2020324_-	hypothetical protein	NA	NA	NA	NA
WP_008467350.1\|2020366_2020744_-	diacylglycerol kinase	NA	NA	NA	NA
WP_002962876.1\|2020733_2021465_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_002962881.1\|2021451_2022354_-	cation transporter	A0A1V0SED0	Indivirus	1.5e-08	38.1
WP_016899515.1\|2022354_2023968_-	phosphoethanolamine--lipid A transferase	NA	NA	NA	NA
WP_076920499.1\|2024167_2027368_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.6e-62	22.8
WP_089368379.1\|2027380_2028727_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_024603421.1\|2028789_2030028_-	TolC family protein	NA	NA	NA	NA
WP_010554760.1\|2030132_2030480_-	hypothetical protein	NA	NA	NA	NA
WP_008467336.1\|2031092_2031716_-	recombinase family protein	NA	NA	NA	NA
WP_033011277.1\|2032066_2032438_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_016899520.1\|2032628_2032976_+	mercury transporter	NA	NA	NA	NA
WP_008110847.1\|2033022_2033307_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_008467331.1\|2033306_2033726_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_008467329.1\|2033746_2035186_+	mercury(II) reductase	NA	NA	NA	NA
WP_008110853.1\|2035299_2035737_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_076915769.1\|2035906_2038906_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.5e-28	25.5
WP_089368380.1\|2039521_2040208_-	hypothetical protein	NA	NA	NA	NA
WP_076920568.1\|2040217_2041528_-	hypothetical protein	Q858S9	Enterobacteria_phage	4.2e-65	34.2
WP_008467385.1\|2041975_2042317_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_010554756.1\|2042313_2042664_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.6e-19	44.9
WP_008467384.1\|2042744_2044226_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	1.9e-61	35.1

DBSCAN-SWA_10

3052721 : 3092120

Burkholderia_virus(18.18%)

transposase,tRNA,integrase

attL 3074577:3074598|attR 3092220:3092241

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089368765.1\|3052721_3053375_+\|tRNA	bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	A0A2H4UV25	Bodo_saltans_virus	1.4e-08	29.5
WP_089368766.1\|3053467_3054478_+	DUF3530 family protein	NA	NA	NA	NA
WP_089368767.1\|3054460_3055321_-	co-chaperone DjlA	NA	NA	NA	NA
WP_058374205.1\|3055338_3055992_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_089368768.1\|3055988_3056990_-	phosphotransferase	NA	NA	NA	NA
WP_041454580.1\|3057083_3059330_+	LPS assembly protein LptD	NA	NA	NA	NA
WP_011329281.1\|3059428_3060724_+	peptidylprolyl isomerase SurA	NA	NA	NA	NA
WP_011329282.1\|3060726_3061719_+	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_011329283.1\|3061715_3062522_+	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_011329284.1\|3062505_3062895_+	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_089368769.1\|3062907_3063726_+	symmetrical bis(5'-nucleosyl)-tetraphosphatase	A0A291L9W7	Bordetella_phage	1.0e-08	27.5
WP_089368770.1\|3063978_3065994_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.0e-18	34.5
WP_089368771.1\|3066050_3066536_-	transcription/translation regulatory transformer protein RfaH	NA	NA	NA	NA
WP_004335545.1\|3066852_3067008_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_041454777.1\|3067019_3067256_-	50S ribosomal protein L28	NA	NA	NA	NA
WP_011329290.1\|3067529_3068204_-	DNA repair protein RadC	NA	NA	NA	NA
WP_011329291.1\|3068347_3069541_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	5.6e-40	31.1
WP_011329292.1\|3069699_3070287_+	nucleoid occlusion factor SlmA	NA	NA	NA	NA
WP_089368772.1\|3070448_3073229_+	S9 family peptidase	NA	NA	NA	NA
WP_089368773.1\|3073348_3074455_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	2.0e-20	37.5
3074577:3074598	attL	NA	NA	NA	NA
WP_147207653.1\|3074955_3075192_-	hypothetical protein	NA	NA	NA	NA
WP_089368984.1\|3075471_3076652_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.1e-115	65.1
WP_013463092.1\|3077655_3078228_+	YolA family protein	I6NTM5	Burkholderia_phage	3.2e-33	53.8
WP_013463093.1\|3078271_3078709_-	hypothetical protein	NA	NA	NA	NA
WP_024606317.1\|3078949_3079330_-	hypothetical protein	NA	NA	NA	NA
WP_089368775.1\|3079502_3080722_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.9e-90	59.1
WP_024606314.1\|3080932_3081652_+	hypothetical protein	NA	NA	NA	NA
WP_008465246.1\|3081777_3082980_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.8e-78	73.6
WP_089368985.1\|3083015_3083330_+	DUF4879 domain-containing protein	NA	NA	NA	NA
WP_024604508.1\|3083388_3083832_-	hypothetical protein	NA	NA	NA	NA
WP_024604507.1\|3084247_3084841_-	recombinase family protein	A0A219Y9V9	Aeromonas_phage	5.6e-25	39.2
WP_024604506.1\|3084965_3085478_+	hypothetical protein	NA	NA	NA	NA
WP_013463096.1\|3085598_3086273_+	hypothetical protein	NA	NA	NA	NA
WP_089368776.1\|3087229_3088448_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.9e-90	59.1
WP_089368777.1\|3089167_3091306_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_089368778.1\|3091292_3092120_-\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
3092220:3092241	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP011038

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011038_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011038_1

6033-6150

Orphan

Consensus_repeat	Method
AAACTGCCCCAATTAATGGGGCGAATAAACTTTCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011038_1

>merge|NZ_CP011038|1|6033-6150|CRISPRCasFinder
AAACTGCCCCAATTAATGGGGCGAATAAACTTTCCCACCCCTATAGGGGCGCTATTTTAGAACACACTTAATTAAAATTGAAAACTGCCCCCAATTAATGGGGCGAATAAACTTTCCC

>NZ_CP011038|1|1|6033-6150|CRISPRCasFinder
AAACTGCCCCAATTAATGGGGCGAATAAACTTTCCC	ACCCCTATAGGGGCGCTATTTTAGAACACACTTAATTAAAATTGAA
AACTGCCCCCAATTAATGGGGCGAATAAACTTTCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011038.1\|WP_157696016.1\|7010_7175_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011038.1\|WP_089369347.1\|13774_14020_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011038.1\|WP_089369349.1\|14352_14559_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP011038.1\|WP_089369361.1\|11163_12036_-\|DNA-replication-terminus-site-binding-protein	unknown	unknown	gnl\|CDD\|235090
NZ_CP011038.1\|WP_089369345.1\|12329_12869_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011038.1\|WP_089369340.1\|1369_2452_+\|chromosome-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|370113
NZ_CP011038.1\|WP_089369344.1\|9432_10978_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP011038.1\|WP_089369342.1\|6520_7009_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011038.1\|WP_089369341.1\|3892_5419_+\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP011038.1\|WP_089369339.1\|159_1365_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NZ_CP011038.1\|WP_089369343.1\|8376_8658_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274760
NZ_CP011038.1\|WP_147207684.1\|3530_3836_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NZ_CP011038.1\|WP_086998905.1\|2824_3085_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|181818
NZ_CP011038.1\|WP_089369346.1\|12933_13704_-\|DUF2726-domain-containing-protein	unknown	unknown	gnl\|CDD\|371282
NZ_CP011038.1\|WP_089369350.1\|14632_16504_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP011038.1\|WP_089369344.1\|9432_10978_-\|IS3-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.09711e-22
NZ_CP011038.1\|WP_089369341.1\|3892_5419_+\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	3.92494e-113
NZ_CP011038.1\|WP_089369339.1\|159_1365_+\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	2.95721e-32
NZ_CP011038.1\|WP_089369343.1\|8376_8658_+\|hypothetical-protein	gnl\|CDD\|274760	TIGR03743, SXT_TraD, conjugative coupling factor TraD, SXT/TOL subfamily. Members of this protein family are the putative conjugative coupling factor, TraD (or TraG), rather distantly related to the well-characterized TraD of the F plasmid. Members are associated with conjugative-transposon-like mobile genetic elements of the class that includes SXT, an antibiotic resistance transfer element in some Vibrio cholerae strains. [Mobile and extrachromosomal element functions, Other].	0.000387325
NZ_CP011038.1\|WP_147207684.1\|3530_3836_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	7.95365e-44
NZ_CP011038.1\|WP_086998905.1\|2824_3085_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	7.66448e-23
NZ_CP011038.1\|WP_089369349.1\|14352_14559_+\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	5.62622e-10
NZ_CP011038.1\|WP_089369346.1\|12933_13704_-\|DUF2726-domain-containing-protein	gnl\|CDD\|371282	pfam10881, DUF2726, Protein of unknown function (DUF2726). This bacterial family of proteins has no known function.	8.55712e-50
NZ_CP011038.1\|WP_089369361.1\|11163_12036_-\|DNA-replication-terminus-site-binding-protein	gnl\|CDD\|235090	PRK02951, PRK02951, DNA replication terminus site-binding protein; Provisional.	5.11488e-82
NZ_CP011038.1\|WP_089369340.1\|1369_2452_+\|chromosome-partitioning-protein-ParB	gnl\|CDD\|370113	pfam08775, ParB, ParB family. ParB is a component of the par system which mediates accurate DNA partition during cell division. It recognizes A-box and B-box DNA motifs. ParB forms an asymmetric dimer with 2 extended helix-turn-helix (HTH) motifs that bind to A-boxes. The HTH motifs emanate from a beta sheet coiled coil DNA binding module. Both DNA binding elements are free to rotate around a flexible linker, this enables them to bind to complex arrays of A- and B-box elements on adjacent DNA arms of the looped partition site.	6.05435e-26

>NZ_CP011038.1|WP_089369341.1|3892_5419_+|IS66-family-transposase
MPDTILITELQNQLALMQAKLDALEKDKISLQEDKVEMQARIDHLLAELKLSKSQKYGKKSEKAPRGTFNEAEQHKSTEPPKHHKKGKQTLAAHFEREEVEHTLTVLDCPCCGEQLHHCGSEDSEQVKIIPAKVSVIKHKQFKYACRHCEHEQLTSKIITAPKPKQPIPGSIASPEALAAIVTGKYCDALPLYRLVDILGRGGLELSRGTLANWCIKAGLLIKPLVAAMQRHLLGEHSLCADETRTQVLDEGENPNSNSYMWVYRSNEASDEPVVIYGYQAGRSRACAEEFLAGYQGYLQCDGYCVYDGIEGIIPVGCWAHARRKYDEALKAESKNKGRAHKAISFISQLYKLETQAKNKKLSPQARYQLRQEKALPILLQFKAWLDEASDKVTAGSYIGKAIKYNLNQWHKLIRYVEDCHLGIDNNITERDIRPFTTGRKNWLFSKSVNGAQASATLYSIVMTCRANDINTYYYFLHLFKTLPSRDVGDDDFTDLMPWNVQLDFDYS
>NZ_CP011038.1|WP_147207684.1|3530_3836_+|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MRKSINGLSIIVSDTLSLDPLSQAWFVFCNKQRDKLKILFWDTNGFWLYYRRLEQGRFQWPKETNEHTAMGIEQRQLQWLLSGLPVSNQTRHLALSGLSVM
>NZ_CP011038.1|WP_086998905.1|2824_3085_-|helix-turn-helix-domain-containing-protein
MSIRSFSRYFKANQGISFKLWLNNLRLNRSQELLESTALSITHISEQAGFSSEQIFRKHFKQRFDTTPNAWRNLFRSKVASAEPHI
>NZ_CP011038.1|WP_089369340.1|1369_2452_+|chromosome-partitioning-protein-ParB
MARKRGIRSPLGNAVGAQDAIESGQKSNIESLAKQLKAEVTGSKLSIMDVLQTHLGISNVGESVSWKLKSGKIAQFVPVTLSYQQVKELTSVTFEVNGRDQSGLTKESLQDLDSLCIQQYYPAIGRRVNGVIDLLDGSRRRARFLLEVGKINSFKILVTDDDISSGDAKALAKQLQVSKEHNLREIGMRCQLESQLYEKKYNKKLTQSELAEEMGLSQAKVSKALTAASIDSAIIELFPDISLLSHSDYKVLNTVQKTLGENVNEFIKDIESNIININSELVQDDYKEAVLKIVTDAIKTYKPKPTEQAIVTPLANFSKKNTYARKRVKGRKFAYEFSQLTKEVQDTLDQAIAKVLQDSL
>NZ_CP011038.1|WP_089369339.1|159_1365_+|ParA-family-protein
MTIEKTTHIFQDLKEGADRYIKRRNQRLLVNHRKELRSFTRAEASIYLDIDVKTLDRYCASLGIDPRRHEDAQWSIDIEEIYKVRDSLSVELRKEPKFKRSDKQKAQIIVIQNQKGGVGKTVSSATIGSGLATEFHQEYRVGLIDMDGQATLSMYYAPESAQEGCLSVGDLIMGNYELDENETKKEAISSAFLPTTIPNLRILPASQSDRGIEGWFHEGVFNKSLSSPYSILSKILNEVEDEFDIIIIDTPPSLGYATYNAYYAATSVLFPLSITENDIDATCSYFSYIPQVWGLLNNAKHQGYDFMKILITNHKDSSTTTELLNSLNDSFSPYLYSKEFKNSEAVRQASSLLSTVFDMSKSEYPKSKMSYQVAQQNAYEVTSQLQRDIVNVWRKQEQEQE
>NZ_CP011038.1|WP_089369342.1|6520_7009_+|hypothetical-protein
MNNDVLEIIEYLTSKKDELASQLESLVDEYWVTWRDTNRNIISQSGNPDSVARVGAVAPSIRVYATKAHDRIILRWRIYENSWARLNAAKQDKQTLRYAKEIKRNKDGTTSCFKLTKEAVSWEVEQIDRFLSEAEPVITLINSIHQSLKLLNKLNTKATTEL
>NZ_CP011038.1|WP_157696016.1|7010_7175_+|hypothetical-protein
MTNKTQKAKSLTPEIKTQAQQRAVTKHSGRMKTITTTIKYKTDHTHSFLNQPPA
>NZ_CP011038.1|WP_089369343.1|8376_8658_+|hypothetical-protein
MSSKYNRTDGRYVEFLFRPIYEVNTAIAYGIGAITTPFMTLGSFQPGVTISFGIAGILAGGSYLYARKATPLIQRQQNQVINEFKRQNLNEEK
>NZ_CP011038.1|WP_089369344.1|9432_10978_-|IS3-family-transposase
MRRRFTHEFKVQAVEKALSQCDDVRLEDIALDLGIGYSTLQRWIALAKNHELETKNNGSHMTTEKRPHDWSLEERLNAIIECASLDEAALNEYCRAKGLYPHHIKQWKQDFAKGPSTKPVKSDSKQLRQEIKQLQKELNRKDKALAETAALLVLKKKQMRFLGFQRGRLTHSTERHELIKLITDAQKSGARQAKACELLGLTARTIQRWIEADDMTDKRTSTIKRPPNRLTELEQQRIIKTVNSIEYGHLPPSKIVPKLLDKGVWIASESSFYRVMKSHKLLTHREKVKPNKKIKKPKALKATRVNEIYTWDITYLPTAVKGQFLYLYLVMDIYSRKIVGWQVHDTQLSTLAADLMIDICRREQVKPDQVTLHSDNGSPMKGATLLATLQELGIVPSFSRPSVSNDNPYSESLFKTLKYRPEYPEKAFESMGSARKWVSGFVDWYNDEHLHSGIKFVTPNQRHLGLDKAILAKRHQVNEMAKLQNPSRWSGKSRDWTMINEVNLNPEKKEAMRAA
>NZ_CP011038.1|WP_089369361.1|11163_12036_-|DNA-replication-terminus-site-binding-protein
MHFITDRFDELKNNIRSLNTILTHTQPLAALAYPLPCTSKGMESEPVKYIAAEEHTGHKAVELAASCYQDLYIQPGYSQKSARRTVGVIWLSPAQNPTSITIPELVDKINAAKTDIENHIIQTYETRQDRFEALRAECPGIMTMHLYRHIRCYSEQNIQSIRFAWQRKDSLSKPVKKDLLLKIEEEFDRSGPEYRVPLEQLINRIKQTPGELLRIRRQVRVQPAANIRFDAGIKTVTAPMPIIIIQSNELKLKALTDFDAKSQRKIRSDKAVSEVIGSFGGVTIEVFSAR
>NZ_CP011038.1|WP_089369345.1|12329_12869_-|hypothetical-protein
MQKLKGKLTDITVSHTFKTNKTTLNIYDYLEIDSVRYGNVQVPDVINRHLVDGVGKEFELDYLEVKDGKNLKRTIVGITTENGKYDHIPDIELKGDLTAISTLYNIRTFMYFMIWFIVGGLLSLYLNFKTKSDVAAYALLIVGFIVIFIFSTKEKKRKVVPIKEILEYVKQRKKQSDIR
>NZ_CP011038.1|WP_089369346.1|12933_13704_-|DUF2726-domain-containing-protein
MSLTLIVFIIAVFVFIAIALSGIEKTGSGSPDYTKIGPLFTPAERSFLGVLEQAISNNYRIYGKVRVADVLKTKATKQRSSWQTAFNKIAAKHFDFVLCNMSTMEVICVIELDDKSHNSKRAQERDLFLNNACQGADLKLVRFKAQKSYQIEAVRNAILEATNSLSVSEDVGTPTCNKLELINSERLTSSKLAKKHGLKTSEFLDKMVEYGYLTEINGTHQLTEKGLRNGGEFIEKGRYPAHFKWIEENVPLFKMK
>NZ_CP011038.1|WP_089369347.1|13774_14020_+|hypothetical-protein
MGNKPLIEKYKFKSGKEKLLMLVALAAAAYGLLGLTREYQEGGISLYIIPAFIAIAIGAWSLTKLLNKPIEIDKDKNKENK
>NZ_CP011038.1|WP_089369349.1|14352_14559_+|OmpA-family-protein
MQIIKVAIQGNASSEGGRGYNYNLGKERANAVKGLFLELGVDEKQLVVLSVGERHNNFIPKRTVMQGY
>NZ_CP011038.1|WP_089369350.1|14632_16504_+|hypothetical-protein
MLIKQQVVFQYKSTKNKYFFYILMVLFYLWLEVSFNYFVVSTASDLAVTTDELKFIELFGRFLSCIGCLVLLSRRIKPSGSAAKYCAKFFIMAALAIPTVYFGQKLLIDTLSSMASGDDRMKAVQSDLVKGSFIVAGTPLNITKKINAALLPAFYYSNSTPFVLSDMHLTEITKQKQSKLLSKMYSQFSGLNSKLDEKYQQYVELNKSVDQLNVAYDEKINKTKAAVDTYWEKLKLTENKAWETYRATIKEISNEKLDADLMNKLDSGFRSYRHGGSYSFFKKYEHFTKETVLKGTTPQDWQNGIYLPPKIWGGVDVAAAKRFYHKRYRALLREAKTGFFDEIKDKQNFITQDKVKSQIKEKLASIMTNNIDVEQVNIDDKQGFENSLLKSLYEAKETAILKGSGGVPLGLNKVGFVAYSIEQSPLNLPFTLSTKQSALLFSDYSQENFNAIVATPVTESSIDNIISALNSPPSSFENQSENSQIGTNHFKALLVIPFAISISLFLIIMLSFDLLLHINRYSQINFAKRTESRKIYNKPFYYAQMNPRVALLITMLATLCLISYLHSEWPVKFAFEKVCSFVMAILEGIYYIGESTNGYISIKELFEPLIEYLEALDDLVFPK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011038_1	1.1\|6069\|46\|NZ_CP011038\|CRISPRCasFinder	6069-6114	46	NZ_CP011038	Pseudoalteromonas nigrifaciens strain KMM 661 plasmid unnamed, complete sequence	6069-6114	0	1.0
NZ_CP011038_1	1.1\|6069\|46\|NZ_CP011038\|CRISPRCasFinder	6069-6114	46	NZ_CP011038	Pseudoalteromonas nigrifaciens strain KMM 661 plasmid unnamed, complete sequence	6151-6196	2	0.957

1. spacer 1.1|6069|46|NZ_CP011038|CRISPRCasFinder matches to NZ_CP011038 (Pseudoalteromonas nigrifaciens strain KMM 661 plasmid unnamed, complete sequence) position: , mismatch: 0, identity: 1.0

acccctataggggcgctattttagaacacacttaattaaaattgaa	CRISPR spacer
acccctataggggcgctattttagaacacacttaattaaaattgaa	Protospacer
**********************************************

2. spacer 1.1|6069|46|NZ_CP011038|CRISPRCasFinder matches to NZ_CP011038 (Pseudoalteromonas nigrifaciens strain KMM 661 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.957

acccctataggggcgctattttagaacacacttaattaaaattgaa	CRISPR spacer
gcccctttaggggcgctattttagaacacacttaattaaaattgaa	Protospacer
.***** ***************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP011037

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

452408 : 461437

Micromonas_pusilla_virus(16.67%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089369222.1\|452408_454325_+	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	2.4e-146	48.9
WP_011329986.1\|454514_455657_+	molecular chaperone DnaJ	A0A0P0YNN4	Yellowstone_lake_phycodnavirus	4.5e-23	34.5
WP_089369223.1\|455733_456195_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_041454920.1\|456251_456503_+	hypothetical protein	NA	NA	NA	NA
WP_089369332.1\|456517_457698_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.6e-116	65.7
WP_041454922.1\|457936_458200_+	hypothetical protein	A0A1B0Z0G5	Vibrio_phage	2.1e-08	50.0
WP_089369224.1\|458349_460080_+	sensor histidine kinase	A0A1B0VMK3	Pseudomonas_phage	6.5e-05	30.1
WP_011329990.1\|460072_461437_+	sigma-54-dependent Fis family transcriptional regulator	Q56AR1	Bacillus_thuringiensis_phage	1.1e-07	30.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011036

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP011038

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP011037

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection