CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP022497	Salmonella enterica subsp. enterica serovar Manhattan strain SA20084699 chromosome, complete genome	2 crisprs	DEDDh,c2c9_V-U4,RT,WYL,DinG,cas3,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	3	6	7
NZ_CP022498	Salmonella enterica subsp. enterica serovar Manhattan strain SA20084699 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0
NZ_CP022499	Salmonella enterica subsp. enterica serovar Manhattan strain SA20084699 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022497_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022497_1

4572692-4573391

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
GGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

11 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP022497_1

>merge|NZ_CP022497|1|4572692-4573391|CRISPRCasFinder,CRT,PILER-CR
GTGTTTATCCCCGCTGACGCGGGGAACATTTTTCAGCCCTTGCCGACTGCGGAACGCCCCTCGGTTTATCCCCGCTGGCGCGGGGAACACTGATGCAGGCGTTTACGTACTGCGAGATGAAGCGGTTTATCCCCGCTGGCACGGGGAACACATATTGATACTGTTCTCAAGCGCCGTTTTAGCCGGTTTATCCCCGCTGGCGCGGGGAACACTGGACCGATGGGGCCAACATCGCCGAACGTGGCGGTTTATCCCCGCTGGCGCGGGGAACACCGCCTTACCCCTGCGCATTGGTTGTCTGTTGGCGGTTTATCCCCGCTGGCGCGGGGAACACGTAGTCAGGACCGCTGACGCGTTCGAAATCGTCGGTTTATCCCCGCTGGCGCGGGGAACACGGAAGCTGCATGAGAGCCAGCTACCTGATGAACGGTTTATCCCCGCTGGCGCGGGGAACACCGTCTATGCGGATTGGATTTGATGAGCGTATCCGGTTTATCCCCGCTGGCGCGGGGAACACAATTTAAAACGTGATTCATGTCTGATTTTTTGCGGTTTATCCCCGCTGGCGCGGGGAACACGCGCTTATTCGTCAGCCAATCGACGAGGCTATTGGTTTATCCCCGCTGGCGCGGGGAACACCAAGCGCATCTAACTCCCCCTTTGCTTTTTTCCGGTTTATCCCCGCTGGCGCAGGGAACAC

>NZ_CP022497|1|1|4572692-4573391|CRISPRCasFinder
GTGTTTATCCCCGCTGACGCGGGGAACAT	TTTTCAGCCCTTGCCGACTGCGGAACGCCCCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATGCAGGCGTTTACGTACTGCGAGATGAAG
CGGTTTATCCCCGCTGGCACGGGGAACAC	ATATTGATACTGTTCTCAAGCGCCGTTTTAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGGACCGATGGGGCCAACATCGCCGAACGTGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCCTTACCCCTGCGCATTGGTTGTCTGTTGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTAGTCAGGACCGCTGACGCGTTCGAAATCGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGAAGCTGCATGAGAGCCAGCTACCTGATGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGTCTATGCGGATTGGATTTGATGAGCGTATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTAAAACGTGATTCATGTCTGATTTTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCTTATTCGTCAGCCAATCGACGAGGCTAT
TGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAGCGCATCTAACTCCCCCTTTGCTTTTTTC
CGGTTTATCCCCGCTGGCGCAGGGAACAC

>NZ_CP022497|1|1|4572692-4573391|CRT
GTGTTTATCCCCGCTGACGCGGGGAACAT	TTTTCAGCCCTTGCCGACTGCGGAACGCCCCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATGCAGGCGTTTACGTACTGCGAGATGAAG
CGGTTTATCCCCGCTGGCACGGGGAACAC	ATATTGATACTGTTCTCAAGCGCCGTTTTAGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGGACCGATGGGGCCAACATCGCCGAACGTGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCCTTACCCCTGCGCATTGGTTGTCTGTTGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTAGTCAGGACCGCTGACGCGTTCGAAATCGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGAAGCTGCATGAGAGCCAGCTACCTGATGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGTCTATGCGGATTGGATTTGATGAGCGTATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AATTTAAAACGTGATTCATGTCTGATTTTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCGCTTATTCGTCAGCCAATCGACGAGGCTAT
TGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAGCGCATCTAACTCCCCCTTTGCTTTTTTC
CGGTTTATCCCCGCTGGCGCAGGGAACAC

>NZ_CP022497|1|1|4572694-4573391|PILER-CR
GTTTATCCCCGCTGACGCGGGGAACATT	TTTCAGCCCTTGCCGACTGCGGAACGCCCCTCG
GTTTATCCCCGCTGGCGCGGGGAACACT	GATGCAGGCGTTTACGTACTGCGAGATGAAGCG
GTTTATCCCCGCTGGCACGGGGAACACA	TATTGATACTGTTCTCAAGCGCCGTTTTAGCCG
GTTTATCCCCGCTGGCGCGGGGAACACT	GGACCGATGGGGCCAACATCGCCGAACGTGGCG
GTTTATCCCCGCTGGCGCGGGGAACACC	GCCTTACCCCTGCGCATTGGTTGTCTGTTGGCG
GTTTATCCCCGCTGGCGCGGGGAACACG	TAGTCAGGACCGCTGACGCGTTCGAAATCGTCG
GTTTATCCCCGCTGGCGCGGGGAACACG	GAAGCTGCATGAGAGCCAGCTACCTGATGAACG
GTTTATCCCCGCTGGCGCGGGGAACACC	GTCTATGCGGATTGGATTTGATGAGCGTATCCG
GTTTATCCCCGCTGGCGCGGGGAACACA	ATTTAAAACGTGATTCATGTCTGATTTTTTGCG
GTTTATCCCCGCTGGCGCGGGGAACACG	CGCTTATTCGTCAGCCAATCGACGAGGCTATTG
GTTTATCCCCGCTGGCGCGGGGAACACC	AAGCGCATCTAACTCCCCCTTTGCTTTTTTCCG
GTTTATCCCCGCTGGCGCAGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022497.1\|WP_000741649.1\|4566825_4567536_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP022497.1\|WP_000368586.1\|4577703_4579263_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP022497.1\|WP_001219244.1\|4566346_4566826_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP022497.1\|WP_000490481.1\|4571630_4572677_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP022497.1\|WP_020437813.1\|4577158_4577707_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP022497.1\|WP_000517480.1\|4567554_4567866_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP022497.1\|WP_001118109.1\|4568056_4568413_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP022497.1\|WP_023259900.1\|4579274_4581938_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP022497.1\|WP_020437812.1\|4576086_4577145_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP022497.1\|WP_001173662.1\|4568430_4569036_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP022497.1\|WP_020437817.1\|4583547_4584282_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP022497.1\|WP_024143111.1\|4582381_4583335_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP022497.1\|WP_001221537.1\|4564558_4565320_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP022497.1\|WP_020437811.1\|4575329_4576076_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP022497.1\|WP_000144836.1\|4573780_4574701_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP022497.1\|WP_020437810.1\|4574697_4575348_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP022497.1\|WP_001092256.1\|4569022_4570462_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP022497.1\|WP_000134246.1\|4565300_4566350_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP022497.1\|WP_000372384.1\|4570471_4571380_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP022497.1\|WP_001518648.1\|4573487_4573781_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930

Protein	Function_ID	Function_description	E-value
NZ_CP022497.1\|WP_000741649.1\|4566825_4567536_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	2.24126e-119
NZ_CP022497.1\|WP_000368586.1\|4577703_4579263_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	5.17383e-173
NZ_CP022497.1\|WP_001219244.1\|4566346_4566826_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.27909e-104
NZ_CP022497.1\|WP_000490481.1\|4571630_4572677_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP022497.1\|WP_020437813.1\|4577158_4577707_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.36817e-32
NZ_CP022497.1\|WP_000517480.1\|4567554_4567866_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
NZ_CP022497.1\|WP_001118109.1\|4568056_4568413_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	4.85353e-49
NZ_CP022497.1\|WP_023259900.1\|4579274_4581938_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP022497.1\|WP_020437812.1\|4576086_4577145_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.71017e-137
NZ_CP022497.1\|WP_001173662.1\|4568430_4569036_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	3.92486e-146
NZ_CP022497.1\|WP_020437817.1\|4583547_4584282_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.47425e-138
NZ_CP022497.1\|WP_024143111.1\|4582381_4583335_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP022497.1\|WP_001221537.1\|4564558_4565320_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	7.64916e-147
NZ_CP022497.1\|WP_020437811.1\|4575329_4576076_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.09777e-48
NZ_CP022497.1\|WP_000144836.1\|4573780_4574701_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	9.54577e-157
NZ_CP022497.1\|WP_020437810.1\|4574697_4575348_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	3.88638e-73
NZ_CP022497.1\|WP_001092256.1\|4569022_4570462_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP022497.1\|WP_000134246.1\|4565300_4566350_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP022497.1\|WP_000372384.1\|4570471_4571380_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP022497.1\|WP_001518648.1\|4573487_4573781_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62

>NZ_CP022497.1|WP_000490481.1|4571630_4572677_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NZ_CP022497.1|WP_000372384.1|4570471_4571380_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NZ_CP022497.1|WP_001092256.1|4569022_4570462_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NZ_CP022497.1|WP_001173662.1|4568430_4569036_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLDGEQLVTNLVSQLLDLLRRRDIIRS
>NZ_CP022497.1|WP_001118109.1|4568056_4568413_-|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>NZ_CP022497.1|WP_000517480.1|4567554_4567866_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NZ_CP022497.1|WP_000741649.1|4566825_4567536_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NZ_CP022497.1|WP_001219244.1|4566346_4566826_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NZ_CP022497.1|WP_000134246.1|4565300_4566350_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NZ_CP022497.1|WP_001221537.1|4564558_4565320_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQIKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>NZ_CP022497.1|WP_001518648.1|4573487_4573781_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>NZ_CP022497.1|WP_000144836.1|4573780_4574701_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLINKTGVRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPESLGDSGHRGHG
>NZ_CP022497.1|WP_020437810.1|4574697_4575348_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASAIFDAQTRPFAPMLSAGQTLRFNLRANPTVCKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALTWLARQGEQNGFTLREASVDAYRQQQIRREKSRQMIQFSSVDYTGVLVLNDPVLFLRRLAQGYGKSRAFGCGMMMIKPGDDA
>NZ_CP022497.1|WP_020437811.1|4575329_4576076_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGSAADVLREAYRQYQDKFNALKLPLPRLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NZ_CP022497.1|WP_020437812.1|4576086_4577145_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGAKRLRISSQSLKRAWRTSELFEQALAGNIGIRTGRIAREAAQILIDSGIDAKKAVEYVEKIANCFGKVKAEKKPKDELTNAETEQLVHISPAEFEGVKALAHRLAEEKRAPQEEELALLRKDRMAVDIAMFGRMLANKPDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMKDVLDFICA
>NZ_CP022497.1|WP_020437813.1|4577158_4577707_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVQEDHKATLRKWHEDLQEKRGARASLRRSKTVNEACLSEGFHLLLMQTHSLWKNKADWHVTALAITAVLAAHIKFIDERQSFATQLGQKKSGDNPVMSKLRFSRLSAVKTPEELLRQLRRAVQLLDGSVNLISLADDIFRWCQEQDDLLSHHRRQQRPTEFLRIRWALEYYQAGDNEQD
>NZ_CP022497.1|WP_000368586.1|4577703_4579263_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVNLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADALHKALAPLEHAFQFGAETPSFMQDFEELPDNKITIASLLPETPGIQTTELNTDHFIKRGVMECFCPHCAALALFSMQLNAPSGGQGYRTGLRGGGPLTTLIELQEYQGERQTPLWRKLWLNVMPQDAADLPLPVVYDAAVFPWLAATRTSEPPAHTITTDEQVNKLQAYWGMPRRIRLDFATIRQGVCNICGNNSDELLIQMLVKNYGVNYDRWRHPLTPHRLQIKNSKGFEPVITQPGGLLWRDWLGLSQENPTEKNTEYPAQVIKVFNARELRNIKVGLWGFGADFKKMKIRCWYEHHFPLLMTEGLIPDLRKATQTATRLLSLLRSALKEAWFANAKGARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP022497.1|WP_023259900.1|4579274_4581938_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETNGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSARKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPDSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEESCLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQMLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQKGKFYCDRAFARQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDGVVTPYTSGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDCAACGYSANEGLIGMMGE
>NZ_CP022497.1|WP_024143111.1|4582381_4583335_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMDVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLV
>NZ_CP022497.1|WP_020437817.1|4583547_4584282_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNDLPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQESRYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: NZ_CP022497_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022497_2

4589675-4589826

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACACA	CRISPRCasFinder

2 spacers

cas3,cas8e,cse2gr11,cas7

The CRISPR arrays of NZ_CP022497_2

>merge|NZ_CP022497|2|4589675-4589826|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACACGGCTACACGCAAAAATTCCAGTCGTTGGCGCACGGTTTATCCCCGCTGGCGCGGGGAACACAAAGGGAGCCAAATCTGCCGCATGACCATCGTCGGTTTATCCCCGCTGGCGCGGGGAACACA

>NZ_CP022497|2|2|4589675-4589826|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACACG	GCTACACGCAAAAATTCCAGTCGTTGGCGCA
CGGTTTATCCCCGCTGGCGCGGGGAACACA	AAGGGAGCCAAATCTGCCGCATGACCATCGT
CGGTTTATCCCCGCTGGCGCGGGGAACACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022497.1\|WP_000178258.1\|4599752_4600259_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
NZ_CP022497.1\|WP_000368586.1\|4577703_4579263_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP022497.1\|WP_017466195.1\|4600740_4601277_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185168
NZ_CP022497.1\|WP_020437813.1\|4577158_4577707_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP022497.1\|WP_020437818.1\|4584383_4586096_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP022497.1\|WP_023259900.1\|4579274_4581938_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP022497.1\|WP_020437820.1\|4588779_4589577_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
NZ_CP022497.1\|WP_000832396.1\|4600273_4600744_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
NZ_CP022497.1\|WP_000108313.1\|4588329_4588692_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP022497.1\|WP_020437812.1\|4576086_4577145_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP022497.1\|WP_000210863.1\|4592309_4593947_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP022497.1\|WP_020437817.1\|4583547_4584282_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP022497.1\|WP_024143111.1\|4582381_4583335_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP022497.1\|WP_076734763.1\|4596247_4598947_+\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|185176
NZ_CP022497.1\|WP_000842511.1\|4595579_4596167_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185169
NZ_CP022497.1\|WP_001044459.1\|4598959_4599733_+\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|185177
NZ_CP022497.1\|WP_020437819.1\|4586095_4587895_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP022497.1\|WP_001199961.1\|4590121_4590793_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP022497.1\|WP_023259806.1\|4594174_4594975_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP022497.1\|WP_000036734.1\|4590928_4592227_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617

Protein	Function_ID	Function_description	E-value
NZ_CP022497.1\|WP_000178258.1\|4599752_4600259_+\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	1.6337e-105
NZ_CP022497.1\|WP_000368586.1\|4577703_4579263_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	5.17383e-173
NZ_CP022497.1\|WP_017466195.1\|4600740_4601277_+\|fimbrial-protein	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	2.30226e-121
NZ_CP022497.1\|WP_020437813.1\|4577158_4577707_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.36817e-32
NZ_CP022497.1\|WP_020437818.1\|4584383_4586096_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP022497.1\|WP_023259900.1\|4579274_4581938_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP022497.1\|WP_020437820.1\|4588779_4589577_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	5.22852e-102
NZ_CP022497.1\|WP_000832396.1\|4600273_4600744_+\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	1.41178e-100
NZ_CP022497.1\|WP_000108313.1\|4588329_4588692_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NZ_CP022497.1\|WP_020437812.1\|4576086_4577145_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.71017e-137
NZ_CP022497.1\|WP_000210863.1\|4592309_4593947_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP022497.1\|WP_020437817.1\|4583547_4584282_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.47425e-138
NZ_CP022497.1\|WP_024143111.1\|4582381_4583335_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP022497.1\|WP_076734763.1\|4596247_4598947_+\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|185176	PRK15273, PRK15273, fimbrial biogenesis outer membrane usher protein.	0
NZ_CP022497.1\|WP_000842511.1\|4595579_4596167_+\|fimbrial-protein	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	6.76622e-100
NZ_CP022497.1\|WP_001044459.1\|4598959_4599733_+\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
NZ_CP022497.1\|WP_020437819.1\|4586095_4587895_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP022497.1\|WP_001199961.1\|4590121_4590793_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
NZ_CP022497.1\|WP_023259806.1\|4594174_4594975_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	4.77884e-158
NZ_CP022497.1\|WP_000036734.1\|4590928_4592227_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0

>NZ_CP022497.1|WP_020437820.1|4588779_4589577_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRGPLPIGENFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIVNIVRHCQNITGIKRIYALVGGFHLRCASPFTMWRVRRFLQEHKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NZ_CP022497.1|WP_000108313.1|4588329_4588692_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NZ_CP022497.1|WP_020437819.1|4586095_4587895_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPAPEGKMSGITLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVMVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAAEGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLNRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NZ_CP022497.1|WP_020437818.1|4584383_4586096_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVKPQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP022497.1|WP_020437817.1|4583547_4584282_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNDLPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQESRYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP022497.1|WP_024143111.1|4582381_4583335_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMDVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLV
>NZ_CP022497.1|WP_023259900.1|4579274_4581938_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETNGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSARKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPDSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEESCLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQMLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQKGKFYCDRAFARQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDGVVTPYTSGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDCAACGYSANEGLIGMMGE
>NZ_CP022497.1|WP_000368586.1|4577703_4579263_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVNLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADALHKALAPLEHAFQFGAETPSFMQDFEELPDNKITIASLLPETPGIQTTELNTDHFIKRGVMECFCPHCAALALFSMQLNAPSGGQGYRTGLRGGGPLTTLIELQEYQGERQTPLWRKLWLNVMPQDAADLPLPVVYDAAVFPWLAATRTSEPPAHTITTDEQVNKLQAYWGMPRRIRLDFATIRQGVCNICGNNSDELLIQMLVKNYGVNYDRWRHPLTPHRLQIKNSKGFEPVITQPGGLLWRDWLGLSQENPTEKNTEYPAQVIKVFNARELRNIKVGLWGFGADFKKMKIRCWYEHHFPLLMTEGLIPDLRKATQTATRLLSLLRSALKEAWFANAKGARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP022497.1|WP_020437813.1|4577158_4577707_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVQEDHKATLRKWHEDLQEKRGARASLRRSKTVNEACLSEGFHLLLMQTHSLWKNKADWHVTALAITAVLAAHIKFIDERQSFATQLGQKKSGDNPVMSKLRFSRLSAVKTPEELLRQLRRAVQLLDGSVNLISLADDIFRWCQEQDDLLSHHRRQQRPTEFLRIRWALEYYQAGDNEQD
>NZ_CP022497.1|WP_020437812.1|4576086_4577145_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGAKRLRISSQSLKRAWRTSELFEQALAGNIGIRTGRIAREAAQILIDSGIDAKKAVEYVEKIANCFGKVKAEKKPKDELTNAETEQLVHISPAEFEGVKALAHRLAEEKRAPQEEELALLRKDRMAVDIAMFGRMLANKPDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMKDVLDFICA
>NZ_CP022497.1|WP_001199961.1|4590121_4590793_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP022497.1|WP_000036734.1|4590928_4592227_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP022497.1|WP_000210863.1|4592309_4593947_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>NZ_CP022497.1|WP_023259806.1|4594174_4594975_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFHVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NZ_CP022497.1|WP_000842511.1|4595579_4596167_+|fimbrial-protein
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDSILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>NZ_CP022497.1|WP_076734763.1|4596247_4598947_+|fimbrial-biogenesis-outer-membrane-usher-protein
MMNNTWKSVLCPIACGVGMLLSVSPYSASGKDIEFNTDFLDVKNRDNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVTQLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDWDPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQASYDHRDDDENTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVISDDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTLHVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASWGVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQGNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVTYNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYNGDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQGAQADGYYSHQGALTDIDLSADYEEGSYRSLGMSLRGGMTLTTQGGALHRGSLAGSTRLLVDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWLAGVKAGETLKVFWDGAAQCEASLPSTFTPELLANALLLPCKMLEGQPPTAPQKSSPLPAQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME
>NZ_CP022497.1|WP_001044459.1|4598959_4599733_+|fimbria/pilus-periplasmic-chaperone
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>NZ_CP022497.1|WP_000178258.1|4599752_4600259_+|fimbrial-protein
MTMLTRWKILVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCTIGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>NZ_CP022497.1|WP_000832396.1|4600273_4600744_+|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGETLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSANALTTNVPELGIELQQNGTVFPPGTSLTIDESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>NZ_CP022497.1|WP_017466195.1|4600740_4601277_+|fimbrial-protein
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFKGSATVSFEYQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP022497_1	1.10\|4573270\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4573270-4573301	32	NZ_CP022497.1	43830-43861	1	0.969
NZ_CP022497_1	1.21\|4573271\|33\|NZ_CP022497\|PILER-CR	4573271-4573303	33	NZ_CP022497.1	43830-43862	1	0.97
NZ_CP022497_2	2.2\|4589766\|31\|NZ_CP022497\|CRISPRCasFinder	4589766-4589796	31	NZ_CP022497.1	2364297-2364327	1	0.968

1. spacer 1.10|4573270|32|NZ_CP022497|CRISPRCasFinder,CRT matches to position: 43830-43861, mismatch: 1, identity: 0.969

gcgcttattcgtcagccaatcgacgaggctat	CRISPR spacer
gcggttattcgtcagccaatcgacgaggctat	Protospacer
*** ****************************

2. spacer 1.21|4573271|33|NZ_CP022497|PILER-CR matches to position: 43830-43862, mismatch: 1, identity: 0.97

gcgcttattcgtcagccaatcgacgaggctatt	CRISPR spacer
gcggttattcgtcagccaatcgacgaggctatt	Protospacer
*** *****************************

3. spacer 2.2|4589766|31|NZ_CP022497|CRISPRCasFinder matches to position: 2364297-2364327, mismatch: 1, identity: 0.968

aagggagccaaatctgccgcatgaccatcgt	CRISPR spacer
aagggagccaaatctgccgcatgaccgtcgt	Protospacer
**************************.****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022497_1	1.4\|4572904\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572904-4572935	32	CP051275	Salmonella phage SW-37, complete genome	24295-24326	1	0.969
NZ_CP022497_1	1.4\|4572904\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572904-4572935	32	KC139516	Salmonella phage FSL SP-016, partial genome	43971-44002	1	0.969
NZ_CP022497_1	1.15\|4572905\|33\|NZ_CP022497\|PILER-CR	4572905-4572937	33	CP051275	Salmonella phage SW-37, complete genome	24294-24326	1	0.97
NZ_CP022497_1	1.15\|4572905\|33\|NZ_CP022497\|PILER-CR	4572905-4572937	33	KC139516	Salmonella phage FSL SP-016, partial genome	43971-44003	1	0.97
NZ_CP022497_1	1.4\|4572904\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572904-4572935	32	JQ182729	Enterobacterial phage mEp390, complete genome	23951-23982	3	0.906
NZ_CP022497_1	1.3\|4572843\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572843-4572874	32	NZ_KY296095	Pseudomonas aeruginosa strain 14057 plasmid p14057-KPC, complete sequence	32689-32720	6	0.812
NZ_CP022497_1	1.3\|4572843\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572843-4572874	32	NZ_CP024631	Pseudomonas aeruginosa strain PA59 plasmid unnamed1, complete sequence	7133-7164	6	0.812
NZ_CP022497_1	1.3\|4572843\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572843-4572874	32	NZ_MH734334	Pseudomonas aeruginosa strain 1011 plasmid p1011-KPC2, complete sequence	45685-45716	6	0.812
NZ_CP022497_1	1.3\|4572843\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572843-4572874	32	NZ_CP020561	Pseudomonas aeruginosa strain CR1 plasmid pCR1, complete sequence	30704-30735	7	0.781
NZ_CP022497_1	1.3\|4572843\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572843-4572874	32	NZ_MN433456	Pseudomonas aeruginosa strain PAB546 plasmid unnamed, complete sequence	30247-30278	7	0.781
NZ_CP022497_1	1.14\|4572844\|33\|NZ_CP022497\|PILER-CR	4572844-4572876	33	NZ_MN433456	Pseudomonas aeruginosa strain PAB546 plasmid unnamed, complete sequence	30247-30279	7	0.788
NZ_CP022497_1	1.14\|4572844\|33\|NZ_CP022497\|PILER-CR	4572844-4572876	33	NZ_CP020561	Pseudomonas aeruginosa strain CR1 plasmid pCR1, complete sequence	30703-30735	7	0.788
NZ_CP022497_1	1.3\|4572843\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572843-4572874	32	NC_021709	Alteromonas mediterranea 615 plasmid unnamed, complete sequence	120479-120510	8	0.75
NZ_CP022497_1	1.2\|4572782\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572782-4572813	32	MN694646	Marine virus AFVG_250M1067, complete genome	6939-6970	9	0.719
NZ_CP022497_1	1.2\|4572782\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572782-4572813	32	MN694813	Marine virus AFVG_250M1071, complete genome	5735-5766	9	0.719
NZ_CP022497_1	1.2\|4572782\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572782-4572813	32	MN694441	Marine virus AFVG_250M1066, complete genome	33070-33101	9	0.719
NZ_CP022497_1	1.2\|4572782\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572782-4572813	32	MN694492	Marine virus AFVG_250M1068, complete genome	6277-6308	9	0.719
NZ_CP022497_1	1.2\|4572782\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572782-4572813	32	MN693639	Marine virus AFVG_250M1070, complete genome	33106-33137	9	0.719
NZ_CP022497_1	1.2\|4572782\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572782-4572813	32	MN694318	Marine virus AFVG_250M1065, complete genome	5478-5509	9	0.719
NZ_CP022497_1	1.2\|4572782\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572782-4572813	32	MN693657	Marine virus AFVG_250M1069, complete genome	6020-6051	9	0.719
NZ_CP022497_1	1.4\|4572904\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572904-4572935	32	NZ_AP022571	Mycolicibacterium poriferae strain JCM 12603 plasmid pJCM12603, complete sequence	153476-153507	10	0.688
NZ_CP022497_1	1.1\|4572721\|32\|NZ_CP022497\|CRISPRCasFinder,CRT	4572721-4572752	32	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	47822-47853	11	0.656

1. spacer 1.4|4572904|32|NZ_CP022497|CRISPRCasFinder,CRT matches to CP051275 (Salmonella phage SW-37, complete genome) position: , mismatch: 1, identity: 0.969

tggaccgatggggccaacatcgccgaacgtgg	CRISPR spacer
cggaccgatggggccaacatcgccgaacgtgg	Protospacer
.*******************************

2. spacer 1.4|4572904|32|NZ_CP022497|CRISPRCasFinder,CRT matches to KC139516 (Salmonella phage FSL SP-016, partial genome) position: , mismatch: 1, identity: 0.969

tggaccgatggggccaacatcgccgaacgtgg	CRISPR spacer
tggaccgatggggccaacatcgccgaatgtgg	Protospacer
***************************.****

3. spacer 1.15|4572905|33|NZ_CP022497|PILER-CR matches to CP051275 (Salmonella phage SW-37, complete genome) position: , mismatch: 1, identity: 0.97

tggaccgatggggccaacatcgccgaacgtggc	CRISPR spacer
cggaccgatggggccaacatcgccgaacgtggc	Protospacer
.********************************

4. spacer 1.15|4572905|33|NZ_CP022497|PILER-CR matches to KC139516 (Salmonella phage FSL SP-016, partial genome) position: , mismatch: 1, identity: 0.97

tggaccgatggggccaacatcgccgaacgtggc	CRISPR spacer
tggaccgatggggccaacatcgccgaatgtggc	Protospacer
***************************.*****

5. spacer 1.4|4572904|32|NZ_CP022497|CRISPRCasFinder,CRT matches to JQ182729 (Enterobacterial phage mEp390, complete genome) position: , mismatch: 3, identity: 0.906

tggaccgatggggccaacatcgccgaacgtgg	CRISPR spacer
tggacctatggggccaacatcaccgaacgtag	Protospacer
****** **************.********.*

6. spacer 1.3|4572843|32|NZ_CP022497|CRISPRCasFinder,CRT matches to NZ_KY296095 (Pseudomonas aeruginosa strain 14057 plasmid p14057-KPC, complete sequence) position: , mismatch: 6, identity: 0.812

atattgatactgttctcaagcgccgttttagc	CRISPR spacer
atattgatgctgttctccagcgcccgatcagc	Protospacer
********.******** ******   *.***

7. spacer 1.3|4572843|32|NZ_CP022497|CRISPRCasFinder,CRT matches to NZ_CP024631 (Pseudomonas aeruginosa strain PA59 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

atattgatactgttctcaagcgccgttttagc	CRISPR spacer
atattgatgctgttctccagcgcccgatcagc	Protospacer
********.******** ******   *.***

8. spacer 1.3|4572843|32|NZ_CP022497|CRISPRCasFinder,CRT matches to NZ_MH734334 (Pseudomonas aeruginosa strain 1011 plasmid p1011-KPC2, complete sequence) position: , mismatch: 6, identity: 0.812

atattgatactgttctcaagcgccgttttagc	CRISPR spacer
atattgatgctgttctccagcgcccgatcagc	Protospacer
********.******** ******   *.***

9. spacer 1.3|4572843|32|NZ_CP022497|CRISPRCasFinder,CRT matches to NZ_CP020561 (Pseudomonas aeruginosa strain CR1 plasmid pCR1, complete sequence) position: , mismatch: 7, identity: 0.781

atattgatactgttctcaagcgccgttttagc	CRISPR spacer
atattgatgctgttctccagcgcccgatccgc	Protospacer
********.******** ******   *. **

10. spacer 1.3|4572843|32|NZ_CP022497|CRISPRCasFinder,CRT matches to NZ_MN433456 (Pseudomonas aeruginosa strain PAB546 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

atattgatactgttctcaagcgccgttttagc	CRISPR spacer
atattgatgctgttctccagcgcccgatccgc	Protospacer
********.******** ******   *. **

11. spacer 1.14|4572844|33|NZ_CP022497|PILER-CR matches to NZ_MN433456 (Pseudomonas aeruginosa strain PAB546 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

atattgatactgttctcaagcgccgttttagcc	CRISPR spacer
atattgatgctgttctccagcgcccgatccgcc	Protospacer
********.******** ******   *. ***

12. spacer 1.14|4572844|33|NZ_CP022497|PILER-CR matches to NZ_CP020561 (Pseudomonas aeruginosa strain CR1 plasmid pCR1, complete sequence) position: , mismatch: 7, identity: 0.788

atattgatactgttctcaagcgccgttttagcc	CRISPR spacer
atattgatgctgttctccagcgcccgatccgcc	Protospacer
********.******** ******   *. ***

13. spacer 1.3|4572843|32|NZ_CP022497|CRISPRCasFinder,CRT matches to NC_021709 (Alteromonas mediterranea 615 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

atattgatactgttctcaagcgccgttttagc	CRISPR spacer
atggtatcgctgttctcaatcgcctttttagc	Protospacer
**. *. ..********** **** *******

14. spacer 1.2|4572782|32|NZ_CP022497|CRISPRCasFinder,CRT matches to MN694646 (Marine virus AFVG_250M1067, complete genome) position: , mismatch: 9, identity: 0.719

tgatgcaggcgtttacgtactgcgagatgaag	CRISPR spacer
ggaaacaggcgttgacatactgcgagattgct	Protospacer
 ** .******** **.*********** .

15. spacer 1.2|4572782|32|NZ_CP022497|CRISPRCasFinder,CRT matches to MN694813 (Marine virus AFVG_250M1071, complete genome) position: , mismatch: 9, identity: 0.719

tgatgcaggcgtttacgtactgcgagatgaag	CRISPR spacer
ggaaacaggcgttgacatactgcgagattgct	Protospacer
 ** .******** **.*********** .

16. spacer 1.2|4572782|32|NZ_CP022497|CRISPRCasFinder,CRT matches to MN694441 (Marine virus AFVG_250M1066, complete genome) position: , mismatch: 9, identity: 0.719

tgatgcaggcgtttacgtactgcgagatgaag	CRISPR spacer
ggaaacaggcgttgacatactgcgagattgct	Protospacer
 ** .******** **.*********** .

17. spacer 1.2|4572782|32|NZ_CP022497|CRISPRCasFinder,CRT matches to MN694492 (Marine virus AFVG_250M1068, complete genome) position: , mismatch: 9, identity: 0.719

tgatgcaggcgtttacgtactgcgagatgaag	CRISPR spacer
ggaaacaggcgttgacatactgcgagattgct	Protospacer
 ** .******** **.*********** .

18. spacer 1.2|4572782|32|NZ_CP022497|CRISPRCasFinder,CRT matches to MN693639 (Marine virus AFVG_250M1070, complete genome) position: , mismatch: 9, identity: 0.719

tgatgcaggcgtttacgtactgcgagatgaag	CRISPR spacer
ggaaacaggcgttgacatactgcgagattgct	Protospacer
 ** .******** **.*********** .

19. spacer 1.2|4572782|32|NZ_CP022497|CRISPRCasFinder,CRT matches to MN694318 (Marine virus AFVG_250M1065, complete genome) position: , mismatch: 9, identity: 0.719

tgatgcaggcgtttacgtactgcgagatgaag	CRISPR spacer
ggaaacaggcgttgacatactgcgagattgct	Protospacer
 ** .******** **.*********** .

20. spacer 1.2|4572782|32|NZ_CP022497|CRISPRCasFinder,CRT matches to MN693657 (Marine virus AFVG_250M1069, complete genome) position: , mismatch: 9, identity: 0.719

tgatgcaggcgtttacgtactgcgagatgaag	CRISPR spacer
ggaaacaggcgttgacatactgcgagattgct	Protospacer
 ** .******** **.*********** .

21. spacer 1.4|4572904|32|NZ_CP022497|CRISPRCasFinder,CRT matches to NZ_AP022571 (Mycolicibacterium poriferae strain JCM 12603 plasmid pJCM12603, complete sequence) position: , mismatch: 10, identity: 0.688

tggaccgatggggccaacatcgccgaacgtgg	CRISPR spacer
cacctggatgggggccacatcgccgaacgagt	Protospacer
..  . ******* * ************* *

22. spacer 1.1|4572721|32|NZ_CP022497|CRISPRCasFinder,CRT matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

ttttcagcccttgccgactgcggaacgcccct	CRISPR spacer
cgccgcacccttgccgactgcgggatgcccga	Protospacer
. ..  .****************.*.****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

152522 : 188714

Cronobacter_phage(73.53%)

tRNA,portal,integrase,terminase,head,holin,capsid,tail

attL 158744:158803|attR 190121:190199

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001264391.1\|152522_153536_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.8e-109	59.5
WP_001144069.1\|153763_153979_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_000918865.1\|154214_155960_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	2.1e-72	38.4
WP_001519776.1\|156109_157957_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	8.4e-35	33.7
WP_001620119.1\|158080_158587_-	G/U mismatch-specific DNA glycosylase	NA	NA	NA	NA
158744:158803	attL	NA	NA	NA	NA
WP_079948317.1\|158933_159431_+	hypothetical protein	NA	NA	NA	NA
WP_079948316.1\|159477_159735_+	hypothetical protein	NA	NA	NA	NA
WP_079948315.1\|159790_160417_+	hypothetical protein	NA	NA	NA	NA
WP_102136625.1\|160409_160580_+	hypothetical protein	NA	NA	NA	NA
WP_045160738.1\|161124_162825_-	hypothetical protein	F1BUJ7	Cronobacter_phage	4.9e-223	81.3
WP_045160248.1\|162827_163373_-	hypothetical protein	F1BUJ9	Cronobacter_phage	3.9e-65	73.6
WP_000267951.1\|163344_164070_-	hypothetical protein	F1BUK1	Cronobacter_phage	6.6e-68	56.4
WP_045160249.1\|164059_164614_-\|tail	tail fiber assembly protein	S4TUB9	Salmonella_phage	3.0e-97	96.7
WP_079948313.1\|164626_166783_-\|tail	phage tail protein	Q6K1H2	Salmonella_virus	9.7e-192	65.4
WP_045160251.1\|166792_167380_-	protein phage	F1BUK5	Cronobacter_phage	1.7e-90	82.6
WP_045160253.1\|167372_168557_-	phage protein	F1BUK6	Cronobacter_phage	2.3e-179	78.6
WP_001002797.1\|168553_168883_-	DUF2590 family protein	F1BUK8	Cronobacter_phage	3.8e-39	72.4
WP_045160255.1\|168879_170850_-\|tail	phage tail tape measure protein	F1BUK9	Cronobacter_phage	1.9e-271	70.1
WP_000411337.1\|171037_171295_-	hypothetical protein	A5X9I7	Aeromonas_virus	3.6e-21	63.4
WP_033567000.1\|171441_171774_-	hypothetical protein	F1BUL2	Cronobacter_phage	1.8e-36	72.7
WP_000175560.1\|171773_172115_-	M15 family metallopeptidase	F1BUL3	Cronobacter_phage	2.2e-50	91.1
WP_001154425.1\|172111_172405_-\|holin	holin	C7BGD7	Burkholderia_phage	1.3e-14	46.2
WP_000166743.1\|172414_172870_-	DUF2597 family protein	F1BUL4	Cronobacter_phage	1.5e-57	72.2
WP_033567001.1\|172866_173994_-	DUF2586 domain-containing protein	F1BUL5	Cronobacter_phage	1.2e-174	83.5
WP_033567002.1\|173990_174698_-	hypothetical protein	F1BUL6	Cronobacter_phage	2.6e-101	76.5
WP_000084220.1\|174694_175201_-\|tail	phage tail protein	F1BUL7	Cronobacter_phage	5.2e-64	69.8
WP_000447487.1\|175197_175686_-\|head	head completion/stabilization protein	F1BUL8	Cronobacter_phage	2.3e-64	82.7
WP_001218537.1\|175746_176448_-\|terminase	terminase	F1BUM0	Cronobacter_phage	9.4e-88	66.8
WP_000550496.1\|176451_177474_-\|capsid	phage major capsid protein, P2 family	F1BUM2	Cronobacter_phage	1.1e-158	81.2
WP_033567003.1\|177535_178339_-\|capsid	phage capsid scaffolding protein	F1BUM4	Cronobacter_phage	4.8e-80	56.8
WP_033567004.1\|178499_180284_+\|terminase	terminase	F1BUM5	Cronobacter_phage	1.2e-288	82.4
WP_000038208.1\|180280_181342_+\|portal	phage portal protein	F1BUM7	Cronobacter_phage	2.3e-162	77.1
WP_001552031.1\|181338_181662_+	ogr/Delta-like zinc finger family protein	F1BUM8	Cronobacter_phage	8.0e-50	92.3
WP_000353141.1\|181635_181842_-	hypothetical protein	NA	NA	NA	NA
WP_079948311.1\|181961_183983_-	replication endonuclease	F1BUM9	Cronobacter_phage	5.1e-296	74.5
WP_079948310.1\|183979_184840_-	DNA adenine methylase	F1BUN1	Cronobacter_phage	1.3e-131	83.1
WP_079948321.1\|184830_185007_-	DUF2732 family protein	NA	NA	NA	NA
WP_079948309.1\|185151_185553_-	hypothetical protein	F1BUN2	Cronobacter_phage	8.9e-51	69.2
WP_000996837.1\|185552_185978_-	hypothetical protein	F1BUN5	Cronobacter_phage	2.2e-23	49.6
WP_079948308.1\|185967_186195_-	DUF2724 domain-containing protein	NA	NA	NA	NA
WP_079948307.1\|186204_186708_-	hypothetical protein	F1BUN6	Cronobacter_phage	4.5e-60	72.5
WP_060683173.1\|186738_186960_-	hypothetical protein	NA	NA	NA	NA
WP_079948306.1\|187092_187680_+	phage repressor protein CI	A0A218M4J1	Erwinia_phage	6.1e-32	38.5
WP_079948305.1\|187679_188714_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.6e-115	58.1
190121:190199	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1212203 : 1230355

Burkholderia_phage(40.0%)

tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001177097.1\|1212203_1212719_-\|tail	tail fiber assembly protein	A0A0U2QV64	Escherichia_phage	3.4e-34	41.2
WP_000368203.1\|1212728_1214210_-\|tail	tail fiber protein	A0A0M3ULF6	Salmonella_phage	1.3e-51	51.7
WP_000359500.1\|1214212_1214845_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	6.6e-24	56.4
WP_020437568.1\|1214837_1215953_-\|plate	phage baseplate	Q6QI99	Burkholderia_phage	3.4e-100	51.7
WP_001093501.1\|1215943_1216303_-\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	2.8e-35	64.2
WP_000632048.1\|1216466_1218014_-	hypothetical protein	B9UDL6	Salmonella_phage	2.5e-48	29.9
WP_020437570.1\|1218013_1218943_-	glycosyltransferase family 2 protein	S5FKN0	Shigella_phage	3.9e-150	83.8
WP_000593184.1\|1218939_1219302_-	GtrA family protein	U5P0S6	Shigella_phage	9.6e-44	70.8
WP_093998229.1\|1219629_1220352_-\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	3.9e-12	42.0
WP_017465889.1\|1220361_1221405_-	phage late control D family protein	A4JWL3	Burkholderia_virus	6.5e-77	45.9
WP_001269716.1\|1221392_1221602_-	membrane protein	A4JWL2	Burkholderia_virus	9.8e-17	60.3
WP_020437572.1\|1221601_1222555_-	hypothetical protein	A4JWL1	Burkholderia_virus	1.0e-36	51.5
WP_020437573.1\|1222554_1224906_-\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	3.6e-67	31.3
WP_001185655.1\|1225002_1225131_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_020437574.1\|1225090_1225408_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_020437575.1\|1225459_1225984_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	3.6e-68	69.5
WP_000729853.1\|1225983_1227411_-\|tail	phage tail sheath family protein	A4JWK5	Burkholderia_virus	1.4e-194	70.9
WP_000875314.1\|1227400_1227598_-	hypothetical protein	Q6QIB1	Burkholderia_phage	8.6e-07	52.9
WP_000449439.1\|1227594_1228050_-	hypothetical protein	NA	NA	NA	NA
WP_000777267.1\|1228208_1228523_-	hypothetical protein	Q6QIC4	Burkholderia_phage	8.3e-20	48.2
WP_020437576.1\|1228535_1229141_-	transglycosylase SLT domain-containing protein	Q5ZQZ1	Pseudomonas_phage	1.4e-60	59.9
WP_001226439.1\|1229143_1229431_-	membrane protein	Q6QIC8	Burkholderia_phage	3.0e-16	48.1
WP_093998230.1\|1230007_1230355_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	1.1e-20	50.5

DBSCAN-SWA_3

2617353 : 2624666

Dickeya_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001201751.1\|2617353_2618472_+	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.4e-08	38.9
WP_000125873.1\|2618468_2620415_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.0e-39	43.1
WP_000447499.1\|2620544_2620766_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
WP_000520787.1\|2621089_2621410_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	3.5e-13	45.7
WP_000934064.1\|2621440_2623717_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.2e-165	42.3
WP_001117984.1\|2623929_2624127_-	hypothetical protein	NA	NA	NA	NA
WP_001531374.1\|2624288_2624666_-	hypothetical protein	A0A077KET4	Ralstonia_phage	1.7e-19	40.2

DBSCAN-SWA_4

2675042 : 2779453

Enterobacteria_phage(29.41%)

lysis,tRNA,portal,integrase,protease,terminase,head,holin,capsid,tail

attL 2677951:2677970|attR 2755341:2755360

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001154025.1\|2675042_2675846_+\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_001288828.1\|2675838_2677161_+	chromosome partition protein MukF	NA	NA	NA	NA
WP_000060024.1\|2677141_2677846_+	chromosome partition protein MukE	NA	NA	NA	NA
WP_000572746.1\|2677845_2682312_+	chromosome partition protein MukB	NA	NA	NA	NA
2677951:2677970	attL	NA	NA	NA	NA
WP_000925890.1\|2682656_2684501_+	L,D-transpeptidase	NA	NA	NA	NA
WP_000357052.1\|2684760_2685309_+	YcbK family protein	A0A0K1LKR7	Rhodobacter_phage	1.2e-05	33.7
WP_001109471.1\|2685336_2685984_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_000462653.1\|2686045_2687236_-	aspartate transaminase	NA	NA	NA	NA
WP_000977709.1\|2687420_2688512_-	porin OmpF	Q1MVN1	Enterobacteria_phage	1.7e-99	51.7
WP_000117867.1\|2689117_2690518_-\|tRNA	asparagine--tRNA ligase	A0A2K9V902	Bandra_megavirus	4.5e-81	35.8
WP_000762343.1\|2690718_2691180_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_020438006.1\|2691496_2692711_+	diaminopropionate ammonia-lyase	NA	NA	NA	NA
WP_023210580.1\|2692956_2694393_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_000191404.1\|2694470_2695673_-	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_093998267.1\|2695867_2697160_-\|integrase	site-specific integrase	S4TSP2	Salmonella_phage	4.5e-253	99.8
WP_000065276.1\|2697204_2697453_-	excisionase family protein	S4TND0	Salmonella_phage	4.7e-42	100.0
WP_001237031.1\|2697493_2697733_-	DUF4060 family protein	S4TR31	Salmonella_phage	2.0e-37	100.0
WP_001539618.1\|2697775_2698933_-	recombinase RecT	S4TTE8	Salmonella_phage	1.6e-217	100.0
WP_001224472.1\|2702554_2702980_-	helix-turn-helix domain-containing protein	K7PH71	Enterobacterial_phage	1.2e-13	56.3
WP_001033909.1\|2703076_2703331_+	helix-turn-helix transcriptional regulator	K7PKH4	Enterobacteria_phage	1.2e-16	59.4
WP_001524722.1\|2703858_2704866_+	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	1.7e-122	67.0
WP_157872077.1\|2704777_2705320_+	replication protein	A0A0U2JGJ0	Escherichia_phage	7.1e-67	74.8
WP_000089415.1\|2705332_2705728_+	DUF977 family protein	A0A088CBK9	Shigella_phage	9.8e-18	38.8
WP_023139984.1\|2706014_2707145_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_079986967.1\|2707541_2709521_+	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	1.5e-162	46.3
WP_162783361.1\|2710151_2710457_+	hypothetical protein	NA	NA	NA	NA
WP_058663890.1\|2710520_2711120_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.0e-95	82.9
WP_001604756.1\|2711116_2711344_+	Bacteriophage lambda NinG	A0A0M4RU10	Salmonella_phage	6.2e-17	72.5
WP_000801757.1\|2711340_2711481_+	YlcG family protein	A0A0M5M7B2	Salmonella_phage	7.2e-08	78.9
WP_080191864.1\|2711477_2712155_+	antiterminator	I6PDF8	Cronobacter_phage	8.6e-62	54.0
WP_093998269.1\|2712427_2712991_+	ORF6N domain-containing protein	A0A0P0ZC44	Stx2-converting_phage	2.9e-55	91.4
WP_001110787.1\|2713902_2714589_-\|protease	type III secretion system effector protease GogA	Q9MBM2	Phage_Gifsy-1	3.6e-132	99.6
WP_162096904.1\|2714864_2715206_+\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	9.6e-46	80.4
WP_093998270.1\|2715208_2715835_+	glycoside hydrolase family 19 protein	Q858F0	Salmonella_phage	8.7e-93	79.2
WP_093998337.1\|2715867_2716317_+\|lysis	lysis protein	A0A0M4RD57	Salmonella_phage	7.2e-57	85.0
WP_000669693.1\|2716552_2716954_-	hypothetical protein	NA	NA	NA	NA
WP_001102153.1\|2717239_2717785_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.5e-56	80.6
WP_039513168.1\|2717756_2719688_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.8e-258	65.7
WP_039513171.1\|2719671_2719875_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	9.5e-17	72.3
WP_023237960.1\|2719871_2721452_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	4.3e-189	63.0
WP_093998271.1\|2721441_2722938_+	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	1.3e-97	52.4
WP_000011260.1\|2722950_2723298_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	9.2e-20	52.7
WP_000522566.1\|2723352_2724381_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.7e-114	61.1
WP_000235459.1\|2724438_2724798_+	DNA packaging protein	NA	NA	NA	NA
WP_046093485.1\|2724808_2725186_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	2.6e-28	53.8
WP_046093484.1\|2725172_2725751_+\|tail	phage tail protein	A5LH33	Enterobacteria_phage	1.1e-81	79.7
WP_046093483.1\|2725747_2726149_+\|tail	tail protein	Q9G0F3	Phage_Gifsy-1	3.1e-51	99.0
WP_000971954.1\|2726156_2726903_+\|tail	tail protein	A0A291AWU6	Escherichia_phage	1.9e-99	76.9
WP_000479607.1\|2726953_2727349_+\|tail	phage minor tail protein G	A5LH36	Enterobacteria_phage	2.3e-30	56.5
WP_093998272.1\|2727345_2727684_+\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	3.0e-31	62.7
WP_093998273.1\|2727655_2730697_+\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	9.2e-289	64.7
WP_000447370.1\|2730699_2731029_+\|tail	phage tail protein	A5LH39	Enterobacteria_phage	7.3e-43	71.3
WP_023229841.1\|2731038_2731737_+\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	1.2e-103	75.9
WP_000662740.1\|2731743_2732481_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.2e-128	84.6
WP_023228907.1\|2732378_2733026_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	5.4e-90	78.6
WP_047588350.1\|2733088_2736451_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	80.2
WP_000178849.1\|2736489_2736732_+	hypothetical protein	NA	NA	NA	NA
WP_093998274.1\|2736785_2739224_+\|tail	phage tail protein	A0A0K2FIZ6	Escherichia_phage	1.4e-90	63.8
WP_093998275.1\|2739223_2739802_+\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	2.3e-87	83.6
WP_031617726.1\|2739898_2740099_-	PhoPQ-activated virulence protein PagK	NA	NA	NA	NA
WP_000457876.1\|2740669_2740795_+	hypothetical protein	NA	NA	NA	NA
WP_001520226.1\|2742328_2744440_+	type III secretion system effector E3 ubiquitin transferase SspH1	Q9MBL9	Phage_Gifsy-2	2.1e-26	46.9
WP_093998276.1\|2744759_2745431_-	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	8.2e-81	60.4
WP_093998277.1\|2745790_2746477_-	virulence protein	NA	NA	NA	NA
WP_000497441.1\|2746747_2746939_-	DinI-like family protein	S4TNM0	Salmonella_phage	6.2e-26	95.2
WP_093998278.1\|2747365_2749978_+	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	2.2e-20	22.8
WP_000291723.1\|2750185_2751196_+	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_001220671.1\|2751361_2751904_+	cell division protein ZapC	NA	NA	NA	NA
WP_020438009.1\|2751900_2753010_-	MOSC domain-containing protein	NA	NA	NA	NA
WP_020438010.1\|2753108_2755217_+	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_020438011.1\|2755229_2757137_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	3.2e-53	29.8
2755341:2755360	attR	NA	NA	NA	NA
WP_000333152.1\|2757151_2758405_+	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_000433416.1\|2758409_2760050_+	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_000759136.1\|2760046_2760610_+	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_001537784.1\|2760865_2761033_+	ribosome modulation factor	NA	NA	NA	NA
WP_000227928.1\|2761132_2761651_-	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_000156454.1\|2761719_2763480_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000877172.1\|2763665_2764118_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_001670727.1\|2764189_2765242_-	porin OmpA	NA	NA	NA	NA
WP_000288732.1\|2765598_2766108_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_001202375.1\|2766324_2766930_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_000950881.1\|2766916_2769070_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_001617378.1\|2769088_2769535_-	YccF domain-containing protein	NA	NA	NA	NA
WP_093998279.1\|2769658_2771713_+	DNA helicase IV	A7KV33	Bacillus_phage	1.1e-19	27.6
WP_000424187.1\|2771748_2772207_-	methylglyoxal synthase	NA	NA	NA	NA
WP_000847732.1\|2772301_2772964_-	DUF2057 family protein	NA	NA	NA	NA
WP_001537782.1\|2773137_2773551_+	CoA-binding protein	NA	NA	NA	NA
WP_000561983.1\|2773595_2773913_-	heat shock protein HspQ	NA	NA	NA	NA
WP_000140482.1\|2773970_2775182_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_020438017.1\|2775396_2775945_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_023259505.1\|2775970_2776750_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000072884.1\|2776798_2777080_+	acylphosphatase	NA	NA	NA	NA
WP_020438019.1\|2777076_2777406_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_000374046.1\|2777492_2778152_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	2.7e-44	52.4
WP_021294418.1\|2778772_2779453_-\|protease	type III secretion system effector protease PipA	Q9MBM0	Phage_Gifsy-2	5.2e-83	72.0

DBSCAN-SWA_5

3679982 : 3690601

Morganella_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001157315.1\|3679982_3681413_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.0e-104	57.4
WP_001748531.1\|3681486_3682182_-	phosphohydrolase	A0A1D6Y7U0	Golden_Marseillevirus	2.8e-07	27.1
WP_000107434.1\|3682261_3682573_-	hypothetical protein	NA	NA	NA	NA
WP_017465542.1\|3683224_3684436_+	porin	Q1MVN1	Enterobacteria_phage	4.4e-109	56.2
WP_024131109.1\|3684695_3684884_-	hypothetical protein	NA	NA	NA	NA
WP_000208509.1\|3684894_3685107_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.9e-21	70.0
WP_000457663.1\|3685561_3686830_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	9.3e-227	91.9
WP_000394197.1\|3686832_3687252_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.5e-36	60.5
WP_001537372.1\|3687378_3687540_-	hypothetical protein	NA	NA	NA	NA
WP_000598921.1\|3688020_3688818_+	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_001683376.1\|3689189_3689480_+	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	2.1e-09	52.6
WP_001219016.1\|3690127_3690601_+	peptidase	A0A0F6TJ61	Escherichia_coli_O157_typing_phage	1.6e-38	76.6

DBSCAN-SWA_6

3778604 : 3789111

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000126351.1\|3778604_3779918_-	lipopolysaccharide biosynthesis protein RfbH	H8ZJ36	Ostreococcus_tauri_virus	9.1e-52	35.1
WP_000565902.1\|3779944_3781024_-	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.3e-16	24.5
WP_000648783.1\|3781028_3781802_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_093998309.1\|3781817_3782792_-	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_000973714.1\|3782797_3783349_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.0e-52	58.0
WP_000857530.1\|3783349_3784228_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	5.1e-107	64.8
WP_001023659.1\|3784275_3785175_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.1e-30	36.0
WP_000697840.1\|3785174_3786260_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.2e-102	53.9
WP_000981469.1\|3786636_3787530_-	GalU regulator GalF	A0A127AW70	Bacillus_phage	4.8e-44	42.2
WP_020437414.1\|3787707_3789111_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	2.3e-21	27.1

DBSCAN-SWA_7

3867565 : 3876736

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000195330.1\|3867565_3869599_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.0e-54	27.6
WP_000703137.1\|3869839_3870298_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	8.4e-53	72.5
WP_023259641.1\|3870469_3871000_+	YehR family lipoprotein	NA	NA	NA	NA
WP_000950413.1\|3871056_3871524_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	3.9e-74	90.3
WP_000598637.1\|3871570_3872290_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000272850.1\|3872286_3873972_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.8e-279	91.3
WP_001240417.1\|3874194_3874926_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	4.5e-101	87.9
WP_001261696.1\|3874985_3875093_+	protein YohO	NA	NA	NA	NA
WP_000824854.1\|3875073_3875805_-	ABC transporter permease	NA	NA	NA	NA
WP_000569166.1\|3875788_3876736_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	3.7e-10	27.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022497

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection