CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022354	Streptococcus pyogenes strain GUR chromosome, complete genome	4 crisprs	DEDDh,cas3,csn2,cas2,cas1,cas9,csm6,DinG,csa3	0	3	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022354_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022354_1

858426-858526

Orphan

Consensus_repeat	Method
TATAATTAGACTATACCAATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022354_1

>merge|NZ_CP022354|1|858426-858526|CRISPRCasFinder
TATAATTAGACTATACCAATTTTATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATACTGTTTTTATCGGTATAATTAGACTATACCAATTAT

>NZ_CP022354|1|1|858426-858526|CRISPRCasFinder
TATAATTAGACTATACCAATTTT	ATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATACTGTTTTTATCGG
TATAATTAGACTATACCAATTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022354.1\|WP_093974691.1\|863532_864306_+\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NZ_CP022354.1\|WP_002989607.1\|849064_849679_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP022354.1\|WP_014635494.1\|862325_863162_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NZ_CP022354.1\|WP_002989605.1\|847703_848324_-\|DUF3862-domain-containing-protein	unknown	unknown	gnl\|CDD\|289729
NZ_CP022354.1\|WP_012560755.1\|866030_867353_-\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NZ_CP022354.1\|WP_002984447.1\|856124_857627_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_CP022354.1\|WP_002992415.1\|861680_862310_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP022354.1\|WP_002984451.1\|858577_860392_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP022354.1\|WP_002992417.1\|861029_861671_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP022354.1\|WP_023078165.1\|864675_865911_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_CP022354.1\|WP_002984433.1\|849809_850595_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_002984449.1\|857844_858402_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP022354.1\|WP_002989617.1\|851302_851674_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_CP022354.1\|WP_002992581.1\|845182_847447_+\|glycogen/starch/alpha-glucan-family-phosphorylase	unknown	unknown	gnl\|CDD\|340853
NZ_CP022354.1\|WP_093974689.1\|860587_860923_+\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NZ_CP022354.1\|WP_002992425.1\|850604_851303_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP022354.1\|WP_002984441.1\|851858_854969_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NZ_CP022354.1\|WP_002989648.1\|867882_870201_+\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_CP022354.1\|WP_002984469.1\|870563_870812_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP022354.1\|WP_002984444.1\|855048_856062_+\|ATP-dependent-6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111

Protein	Function_ID	Function_description	E-value
NZ_CP022354.1\|WP_093974691.1\|863532_864306_+\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	2.92391e-97
NZ_CP022354.1\|WP_002989607.1\|849064_849679_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
NZ_CP022354.1\|WP_014635494.1\|862325_863162_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.58337e-109
NZ_CP022354.1\|WP_002989605.1\|847703_848324_-\|DUF3862-domain-containing-protein	gnl\|CDD\|289729	pfam12978, DUF3862, Domain of Unknown Function with PDB structure (DUF3862). Structure 3D4E shared structural similarity to beta-lactamase inhibitory proteins (BLIP) which already include 1XXM, 1S0W, 1JTG, 2G2U, 2G2W, 2B5R, and 3due. All of structures are involved in beta-lactamase inhibitor complex. (REF http://www.topsan.org/Proteins/JCSG/3d4e).	6.81674e-87
NZ_CP022354.1\|WP_012560755.1\|866030_867353_-\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NZ_CP022354.1\|WP_002984447.1\|856124_857627_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_CP022354.1\|WP_002992415.1\|861680_862310_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	5.61041e-111
NZ_CP022354.1\|WP_002984451.1\|858577_860392_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP022354.1\|WP_002992417.1\|861029_861671_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.99371e-71
NZ_CP022354.1\|WP_023078165.1\|864675_865911_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	9.94289e-96
NZ_CP022354.1\|WP_002984441.1\|851858_854969_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NZ_CP022354.1\|WP_002984449.1\|857844_858402_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38
NZ_CP022354.1\|WP_002989617.1\|851302_851674_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.0536e-49
NZ_CP022354.1\|WP_002992581.1\|845182_847447_+\|glycogen/starch/alpha-glucan-family-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_CP022354.1\|WP_002992425.1\|850604_851303_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.0817e-63
NZ_CP022354.1\|WP_093974689.1\|860587_860923_+\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	1.1987e-64
NZ_CP022354.1\|WP_002989648.1\|867882_870201_+\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP022354.1\|WP_002984469.1\|870563_870812_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NZ_CP022354.1\|WP_002984444.1\|855048_856062_+\|ATP-dependent-6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0

>NZ_CP022354.1|WP_002984449.1|857844_858402_+|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NZ_CP022354.1|WP_002984447.1|856124_857627_+|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NZ_CP022354.1|WP_002984444.1|855048_856062_+|ATP-dependent-6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NZ_CP022354.1|WP_002984441.1|851858_854969_+|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDAKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NZ_CP022354.1|WP_002989617.1|851302_851674_-|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NZ_CP022354.1|WP_002992425.1|850604_851303_-|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDNSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NZ_CP022354.1|WP_002984433.1|849809_850595_-|hypothetical-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NZ_CP022354.1|WP_002989607.1|849064_849679_+|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NZ_CP022354.1|WP_002989605.1|847703_848324_-|DUF3862-domain-containing-protein
MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQFDQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYSQASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE
>NZ_CP022354.1|WP_002992581.1|845182_847447_+|glycogen/starch/alpha-glucan-family-phosphorylase
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGLGRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDDSWLVPTDISYDVPFKNFTLKSRLDRIDVLGYRRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKNLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR
>NZ_CP022354.1|WP_002984451.1|858577_860392_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NZ_CP022354.1|WP_093974689.1|860587_860923_+|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVVLDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCRIDGFGAMKLKSEFVKKI
>NZ_CP022354.1|WP_002992417.1|861029_861671_+|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NZ_CP022354.1|WP_002992415.1|861680_862310_+|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NZ_CP022354.1|WP_014635494.1|862325_863162_+|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKGLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKDRQEKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>NZ_CP022354.1|WP_093974691.1|863532_864306_+|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANLQRDALVQKLDEGYQQLEAIKHEAKGTDIETTVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>NZ_CP022354.1|WP_023078165.1|864675_865911_-|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLLLSVAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQFSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQITPIAKRQLHHTHYRIVKM
>NZ_CP022354.1|WP_012560755.1|866030_867353_-|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>NZ_CP022354.1|WP_002989648.1|867882_870201_+|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NZ_CP022354.1|WP_002984469.1|870563_870812_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022354_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022354_2

1033264-1033827

Orphan

Consensus_repeat	Method
TGGACCTACTGGACCNNNTNNNCC	CRT

8 spacers

The CRISPR arrays of NZ_CP022354_2

>merge|NZ_CP022354|2|1033264-1033827|CRT
TGGACCTACTGGACCACGTTCACCATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACGTGGACCTACTGGACCTGCTGGGCCGGTTTCACCGCGGTCACCTTTAGCACCTGGTTCGCCATCCTTGCCAGCTGGACCTACTGGACCACGTTCACCATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACGTGGACCTACTGGACCTGCTGGGCCGGTTTCACCGCGGTCACCTTTAGCACCTGGTTCGCCATCTTTTCCAGCTGGACCTACTGGACCACGTTCACCATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACGTGGACCTACTGGACCTGCTGGGCCGGTTTCACCGCGGTCACCTTTAGCACCTGGTTCGCCATCTTTTCCAGCTGGACCTACTGGACCACGTTCACCATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACGTGGACCTACTGGACCTGCTGGGCCGGTTTCACCGCGGTCACCTTTAGCACCTGGTTCGCCATCTTTTCCAGCTGGACCTACTGGACCTGCTGGGCC

>NZ_CP022354|2|1|1033264-1033827|CRT
TGGACCTACTGGACCACGTTCACC	ATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACGTGGACCTAC
TGGACCTGCTGGGCCGGTTTCACC	GCGGTCACCTTTAGCACCTGGTTCGCCATCCTTGCCAGC
TGGACCTACTGGACCACGTTCACC	ATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACGTGGACCTAC
TGGACCTGCTGGGCCGGTTTCACC	GCGGTCACCTTTAGCACCTGGTTCGCCATCTTTTCCAGC
TGGACCTACTGGACCACGTTCACC	ATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACG
TGGACCTACTGGACCTGCTGGGCC	GGTTTCACCGCGGTCACCTTTAGCACCTGGTTCGCCATCTTTTCCAGC
TGGACCTACTGGACCACGTTCACC	ATCTTTTCCGGCGGGACCGGCTTCGCCTCGCTCACCACG
TGGACCTACTGGACCTGCTGGGCC	GGTTTCACCGCGGTCACCTTTAGCACCTGGTTCGCCATCTTTTCCAGC
TGGACCTACTGGACCTGCTGGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022354.1\|WP_038432940.1\|1036645_1036792_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP022354.1\|WP_011054447.1\|1038953_1039193_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_029714017.1\|1037407_1037590_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_029714020.1\|1041050_1041278_-\|phage-holin	unknown	unknown	gnl\|CDD\|227833
NZ_CP022354.1\|WP_029714018.1\|1039722_1040928_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|224619
NZ_CP022354.1\|WP_076634216.1\|1030418_1030844_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_CP022354.1\|WP_002984836.1\|1025681_1026470_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_CP022354.1\|WP_023079409.1\|1026473_1028123_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_CP022354.1\|WP_093974698.1\|1031050_1032070_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_CP022354.1\|WP_023610281.1\|1023129_1024527_-\|NAD-dependent-succinate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143418
NZ_CP022354.1\|WP_093974701.1\|1034689_1036522_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP022354.1\|WP_002989931.1\|1028258_1029086_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_CP022354.1\|WP_002984844.1\|1029082_1029892_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_CP022354.1\|WP_014407546.1\|1032199_1032637_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP022354.1\|WP_011054448.1\|1038438_1038690_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_002984845.1\|1029908_1030400_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_CP022354.1\|WP_011017728.1\|1024641_1025688_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270264
NZ_CP022354.1\|WP_011054450.1\|1037788_1037998_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP022354.1\|WP_093974706.1\|1041274_1041547_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_011054446.1\|1039250_1039607_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022354.1\|WP_038432940.1\|1036645_1036792_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	5.69448e-14
NZ_CP022354.1\|WP_029714020.1\|1041050_1041278_-\|phage-holin	gnl\|CDD\|227833	COG5546, COG5546, Small integral membrane protein [Function unknown].	3.77481e-34
NZ_CP022354.1\|WP_029714018.1\|1039722_1040928_-\|CHAP-domain-containing-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	1.04383e-58
NZ_CP022354.1\|WP_076634216.1\|1030418_1030844_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	9.79007e-31
NZ_CP022354.1\|WP_002984836.1\|1025681_1026470_-\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	5.79862e-82
NZ_CP022354.1\|WP_023079409.1\|1026473_1028123_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.69316e-77
NZ_CP022354.1\|WP_093974698.1\|1031050_1032070_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	2.00726e-103
NZ_CP022354.1\|WP_023610281.1\|1023129_1024527_-\|NAD-dependent-succinate-semialdehyde-dehydrogenase	gnl\|CDD\|143418	cd07100, ALDH_SSADH1_GabD1, Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like. Succinate-semialdehyde dehydrogenase 1 (SSADH1, GabD1, EC=1.2.1.16) catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde (SSA) to succinate. SSADH activity in Mycobacterium tuberculosis (Mtb) is encoded by both gabD1 (Rv0234c) and gabD2 (Rv1731). The Mtb GabD1 SSADH1 reportedly is an enzyme of the gamma-aminobutyrate shunt, which forms a functional link between two TCA half-cycles by converting alpha-ketoglutarate to succinate.	0
NZ_CP022354.1\|WP_093974701.1\|1034689_1036522_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP022354.1\|WP_002989931.1\|1028258_1029086_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_CP022354.1\|WP_002984844.1\|1029082_1029892_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
NZ_CP022354.1\|WP_014407546.1\|1032199_1032637_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	7.26176e-84
NZ_CP022354.1\|WP_002984845.1\|1029908_1030400_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
NZ_CP022354.1\|WP_011017728.1\|1024641_1025688_-\|extracellular-solute-binding-protein	gnl\|CDD\|270264	cd13546, PBP2_BitB, Substrate binding domain of a putative iron transporter BitB, a member of the type 2 periplasmic binding fold superfamily. The substrate domain of this group shows a high homology to the periplasmic component of ferric iron transporter (Fbp), but its biochemical characterization has not been performed. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.33783e-91
NZ_CP022354.1\|WP_011054450.1\|1037788_1037998_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.20712e-13

>NZ_CP022354.1|WP_014407546.1|1032199_1032637_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSDELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET
>NZ_CP022354.1|WP_093974698.1|1031050_1032070_-|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALPAWCLGHLFPIIGAPVFAILLGMLLALFYEHRDKTEEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHYLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_CP022354.1|WP_076634216.1|1030418_1030844_-|PTS-sugar-transporter-subunit-IIA
MERKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_CP022354.1|WP_002984845.1|1029908_1030400_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_CP022354.1|WP_002984844.1|1029082_1029892_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>NZ_CP022354.1|WP_002989931.1|1028258_1029086_-|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_CP022354.1|WP_023079409.1|1026473_1028123_-|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_CP022354.1|WP_002984836.1|1025681_1026470_-|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC
>NZ_CP022354.1|WP_011017728.1|1024641_1025688_-|extracellular-solute-binding-protein
MLKLKRKWLLSFLLVIIILAIVNIAMYIFSSSKKDSAKELVILTPNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFESHKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQPALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDVYESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAKQFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKILNTYNRLHEALERGK
>NZ_CP022354.1|WP_023610281.1|1023129_1024527_-|NAD-dependent-succinate-semialdehyde-dehydrogenase
MAYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDHLEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEFLMSMLLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEEAGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLAQIKLALDNGAELVYGGEAIDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTIFSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEHLIYIPNKTNNSNTKV
>NZ_CP022354.1|WP_093974701.1|1034689_1036522_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKMKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDVKK
>NZ_CP022354.1|WP_038432940.1|1036645_1036792_-|nucleoside-diphosphate-kinase
MMRVTNPTDALYGTIRGNFAQALGDDGGIFNMVHGSHSKDSARREIAL
>NZ_CP022354.1|WP_029714017.1|1037407_1037590_-|hypothetical-protein
MLTYDEFKQAIDNGYITADTVAIVRKNGLIFDYVLPHESVRSCEIVIEERVAEVMVELDK
>NZ_CP022354.1|WP_011054450.1|1037788_1037998_-|helix-turn-helix-transcriptional-regulator
MELYEFVGEQIRHQRKLAKLNQSQLAELLDTNQQTIGMMENGKRRATLQDLVKLRKIFNVSVDDFLPKD
>NZ_CP022354.1|WP_011054448.1|1038438_1038690_+|hypothetical-protein
MEYGNKIFEIYNKPFKYRNSSSTNYNKVRASGIEPNTKFVVNKTANINCAVYPRHGSIEKVFYWGDRKITQATAEKRCGYFKG
>NZ_CP022354.1|WP_011054447.1|1038953_1039193_+|hypothetical-protein
MKYFVTDIENIDNITVFEEFGFDFTESEEGIWYTEEKAMFDWWNELAQAIEFLNDNEINAETNELADYITIAKENGFEF
>NZ_CP022354.1|WP_011054446.1|1039250_1039607_+|hypothetical-protein
MTKTTAQRKKSIYINGALEKIYDECSNALRNRTFSGRVMDIAERYDALMGLTEIPELTPQQQMILGEAVLGAFMDRNKIRYLHDAIADTEIDGCLDLAKMVRDLDYAQRLKLIESINI
>NZ_CP022354.1|WP_029714018.1|1039722_1040928_-|CHAP-domain-containing-protein
MAFLDKIKSAVIAEWHTHKILPSLTAAQAILESGCGKHAPHNALFGIKADRSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWEDSIADHGQFLVDNPRYKAVIGEADYKKACHAIKDAGYATASGYADLLIQLIEENNLQEWDAEAIKNKEEQMISSQCREVIEFFINLANAGVGVDKDSFAGWQCADVPCYAAKHWFGVDLWGNAIDLLDSAAAVGWEVHRMPTDANPRTGAFFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNNRDFTGVIGWFYPPYQGDAVTQTVSTEPQTSDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYKQGDTVSFDSEGYANGYYWISYVGDSGKRSYMAIGITDKDGNIISLWGKLV
>NZ_CP022354.1|WP_029714020.1|1041050_1041278_-|phage-holin
MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAVTLLVLLGVVADPTTKGLSDSEQALTYHEPKK
>NZ_CP022354.1|WP_093974706.1|1041274_1041547_-|hypothetical-protein
MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHLKFVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022354_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022354_3

1037173-1037335

Orphan

II-A,II-B

Consensus_repeat	Method
GACCATTCAAAATAGCATAGCTCTAAAACAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP022354_3

>merge|NZ_CP022354|3|1037173-1037335|CRISPRCasFinder
GACCATTCAAAATAGCATAGCTCTAAAACATCCCGTTCCAGATGTTGAGATGTCTAGTGGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACATTCGCTGGTGGTTCTGGACTCACTCTTGAGTTTTGGGACCATTCAAAACAGCATAGCTCGTAAACTA

>NZ_CP022354|3|2|1037173-1037335|CRISPRCasFinder
GACCATTCAAAATAGCATAGCTCTAAAACAT	CCCGTTCCAGATGTTGAGATGTCTAGTGGTTTTGG
GACCATTCAAAACAGCATAGCTCTAAAACAT	TCGCTGGTGGTTCTGGACTCACTCTTGAGTTTTGG
GACCATTCAAAACAGCATAGCTCGTAAACTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022354.1\|WP_038432940.1\|1036645_1036792_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP022354.1\|WP_011054447.1\|1038953_1039193_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_029714017.1\|1037407_1037590_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_029714020.1\|1041050_1041278_-\|phage-holin	unknown	unknown	gnl\|CDD\|227833
NZ_CP022354.1\|WP_029714018.1\|1039722_1040928_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|224619
NZ_CP022354.1\|WP_076634216.1\|1030418_1030844_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_CP022354.1\|WP_023079409.1\|1026473_1028123_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_CP022354.1\|WP_093974698.1\|1031050_1032070_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_CP022354.1\|WP_002988448.1\|1042199_1042628_-\|DUF1617-family-protein	unknown	unknown	gnl\|CDD\|285058
NZ_CP022354.1\|WP_093974700.1\|1032822_1034505_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
NZ_CP022354.1\|WP_093974701.1\|1034689_1036522_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP022354.1\|WP_002989931.1\|1028258_1029086_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_CP022354.1\|WP_002984844.1\|1029082_1029892_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_CP022354.1\|WP_014407546.1\|1032199_1032637_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP022354.1\|WP_011054448.1\|1038438_1038690_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_002984845.1\|1029908_1030400_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_CP022354.1\|WP_093974706.1\|1041274_1041547_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_011054450.1\|1037788_1037998_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP022354.1\|WP_046735270.1\|1041558_1042197_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_011054446.1\|1039250_1039607_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022354.1\|WP_038432940.1\|1036645_1036792_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	5.69448e-14
NZ_CP022354.1\|WP_029714020.1\|1041050_1041278_-\|phage-holin	gnl\|CDD\|227833	COG5546, COG5546, Small integral membrane protein [Function unknown].	3.77481e-34
NZ_CP022354.1\|WP_029714018.1\|1039722_1040928_-\|CHAP-domain-containing-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	1.04383e-58
NZ_CP022354.1\|WP_076634216.1\|1030418_1030844_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	9.79007e-31
NZ_CP022354.1\|WP_023079409.1\|1026473_1028123_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.69316e-77
NZ_CP022354.1\|WP_093974698.1\|1031050_1032070_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	2.00726e-103
NZ_CP022354.1\|WP_093974700.1\|1032822_1034505_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	7.22099e-11
NZ_CP022354.1\|WP_093974701.1\|1034689_1036522_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP022354.1\|WP_002989931.1\|1028258_1029086_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_CP022354.1\|WP_002984844.1\|1029082_1029892_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
NZ_CP022354.1\|WP_014407546.1\|1032199_1032637_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	7.26176e-84
NZ_CP022354.1\|WP_002988448.1\|1042199_1042628_-\|DUF1617-family-protein	gnl\|CDD\|285058	pfam07761, DUF1617, Protein of unknown function (DUF1617). This is a family of sequences from hypothetical bacterial and bacteriophage proteins. The region in question is approximately 150 residues long and is highly conserved throughout the family.	1.70696e-61
NZ_CP022354.1\|WP_002984845.1\|1029908_1030400_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
NZ_CP022354.1\|WP_011054450.1\|1037788_1037998_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.20712e-13

>NZ_CP022354.1|WP_038432940.1|1036645_1036792_-|nucleoside-diphosphate-kinase
MMRVTNPTDALYGTIRGNFAQALGDDGGIFNMVHGSHSKDSARREIAL
>NZ_CP022354.1|WP_093974701.1|1034689_1036522_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKMKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDVKK
>NZ_CP022354.1|WP_093974700.1|1032822_1034505_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKTKQNKTKQNKTKQNKTKQNKTKQNSLLCRYGLTSAAALLLTFGGASAVRADQRTIEMTQGQLQAIREAFPKLEDSVPDYDVLSQHGFYKHLREFEHQLGFYLKTLDQNLSQLQGERGETGPAGPAGPTGARGPAGPQGPRGDKGETGDRGPAGKDGASGAKGERGETGPAGPAGPTGARGPAGPQGPRGDKGETGDRGPAGKDGASGAKGERGETGPQGPQGETGPAGPVGPAGKDGEPGAKGDRGETGPAGPVGPRGERGEAGPAGKDGERGPVGPAGKDGEPGAKGDRGETGPAGPVGPRGERGEAGPAGKDGERGPVGPAGKDGEPGAKGDRGETGPAGPVGPRGERGEAGPAGKDGERGPVGPAGKDGEPGAKGDRGETGPAGPVGPRGERGEAGPAGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPDQSKDVTPAPQDPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQEHN
>NZ_CP022354.1|WP_014407546.1|1032199_1032637_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSDELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET
>NZ_CP022354.1|WP_093974698.1|1031050_1032070_-|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALPAWCLGHLFPIIGAPVFAILLGMLLALFYEHRDKTEEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHYLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_CP022354.1|WP_076634216.1|1030418_1030844_-|PTS-sugar-transporter-subunit-IIA
MERKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_CP022354.1|WP_002984845.1|1029908_1030400_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_CP022354.1|WP_002984844.1|1029082_1029892_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>NZ_CP022354.1|WP_002989931.1|1028258_1029086_-|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_CP022354.1|WP_023079409.1|1026473_1028123_-|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_CP022354.1|WP_029714017.1|1037407_1037590_-|hypothetical-protein
MLTYDEFKQAIDNGYITADTVAIVRKNGLIFDYVLPHESVRSCEIVIEERVAEVMVELDK
>NZ_CP022354.1|WP_011054450.1|1037788_1037998_-|helix-turn-helix-transcriptional-regulator
MELYEFVGEQIRHQRKLAKLNQSQLAELLDTNQQTIGMMENGKRRATLQDLVKLRKIFNVSVDDFLPKD
>NZ_CP022354.1|WP_011054448.1|1038438_1038690_+|hypothetical-protein
MEYGNKIFEIYNKPFKYRNSSSTNYNKVRASGIEPNTKFVVNKTANINCAVYPRHGSIEKVFYWGDRKITQATAEKRCGYFKG
>NZ_CP022354.1|WP_011054447.1|1038953_1039193_+|hypothetical-protein
MKYFVTDIENIDNITVFEEFGFDFTESEEGIWYTEEKAMFDWWNELAQAIEFLNDNEINAETNELADYITIAKENGFEF
>NZ_CP022354.1|WP_011054446.1|1039250_1039607_+|hypothetical-protein
MTKTTAQRKKSIYINGALEKIYDECSNALRNRTFSGRVMDIAERYDALMGLTEIPELTPQQQMILGEAVLGAFMDRNKIRYLHDAIADTEIDGCLDLAKMVRDLDYAQRLKLIESINI
>NZ_CP022354.1|WP_029714018.1|1039722_1040928_-|CHAP-domain-containing-protein
MAFLDKIKSAVIAEWHTHKILPSLTAAQAILESGCGKHAPHNALFGIKADRSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWEDSIADHGQFLVDNPRYKAVIGEADYKKACHAIKDAGYATASGYADLLIQLIEENNLQEWDAEAIKNKEEQMISSQCREVIEFFINLANAGVGVDKDSFAGWQCADVPCYAAKHWFGVDLWGNAIDLLDSAAAVGWEVHRMPTDANPRTGAFFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDALYVGAPARFNNRDFTGVIGWFYPPYQGDAVTQTVSTEPQTSDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYKQGDTVSFDSEGYANGYYWISYVGDSGKRSYMAIGITDKDGNIISLWGKLV
>NZ_CP022354.1|WP_029714020.1|1041050_1041278_-|phage-holin
MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAVTLLVLLGVVADPTTKGLSDSEQALTYHEPKK
>NZ_CP022354.1|WP_093974706.1|1041274_1041547_-|hypothetical-protein
MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHLKFVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA
>NZ_CP022354.1|WP_046735270.1|1041558_1042197_-|hypothetical-protein
MKTLTLSGKPYPIHEGGKVVKTEVRLIGDNGLFIPIELIGDQTAKGADDLIKEGLDAFVREYVTKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQAKSLELVIAKSQKMANLQAIHLLTSGSKVEPDIYKGLLELIEPAKQGEYQAYDVFTVVDSTKEEDGEAGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD
>NZ_CP022354.1|WP_002988448.1|1042199_1042628_-|DUF1617-family-protein
MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKIKEYAKDEGDLIDLYAQKDKDGKFVIDERKNIKLADPTKIDELNDLLSELGNEDITIKGHEYSKRFIDFLEYLAESEDEFTSDEIIIIDNILEEFEESKGE

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Crispr_ID: NZ_CP022354_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022354_4

1075733-1075834

TypeII

II-A

Consensus_repeat	Method
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRISPRCasFinder

1 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP022354_4

>merge|NZ_CP022354|4|1075733-1075834|CRISPRCasFinder
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACAGAAACGGCAGCTAAAAAACTAAAAATTTCGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>NZ_CP022354|4|3|1075733-1075834|CRISPRCasFinder
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	AGAAACGGCAGCTAAAAAACTAAAAATTTC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022354.1\|WP_029713980.1\|1068280_1069627_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|180232
NZ_CP022354.1\|WP_029713988.1\|1074400_1075597_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NZ_CP022354.1\|WP_029713984.1\|1070960_1071680_-\|antirepressor	unknown	unknown	gnl\|CDD\|214989
NZ_CP022354.1\|WP_029713982.1\|1070470_1070677_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_023080001.1\|1083773_1084526_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_CP022354.1\|WP_023080005.1\|1077795_1081899_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP022354.1\|WP_002989951.1\|1076588_1076930_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP022354.1\|WP_032460891.1\|1076926_1077796_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP022354.1\|WP_023080002.1\|1084535_1085666_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP022354.1\|WP_029713983.1\|1070673_1070886_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_023079997.1\|1083009_1083774_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP022354.1\|WP_022554795.1\|1069956_1070214_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_093974719.1\|1073249_1074005_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP022354.1\|WP_029713986.1\|1072188_1072770_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_029713985.1\|1071722_1071950_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_093974721.1\|1075936_1076599_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP022354.1\|WP_023080006.1\|1085728_1086370_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_093974723.1\|1086493_1087849_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP022354.1\|WP_029713981.1\|1069613_1069802_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022354.1\|WP_023610292.1\|1082377_1083010_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884

Protein	Function_ID	Function_description	E-value
NZ_CP022354.1\|WP_029713980.1\|1068280_1069627_-\|replicative-DNA-helicase	gnl\|CDD\|180232	PRK05748, PRK05748, replicative DNA helicase; Provisional.	0
NZ_CP022354.1\|WP_029713988.1\|1074400_1075597_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	1.78029e-19
NZ_CP022354.1\|WP_029713984.1\|1070960_1071680_-\|antirepressor	gnl\|CDD\|214989	smart01040, Bro-N, BRO family, N-terminal domain. This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.	1.74355e-40
NZ_CP022354.1\|WP_023080001.1\|1083773_1084526_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	6.29729e-107
NZ_CP022354.1\|WP_023080005.1\|1077795_1081899_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP022354.1\|WP_002989951.1\|1076588_1076930_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.79e-58
NZ_CP022354.1\|WP_023079997.1\|1083009_1083774_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.30945e-126
NZ_CP022354.1\|WP_032460891.1\|1076926_1077796_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.0115e-131
NZ_CP022354.1\|WP_023080002.1\|1084535_1085666_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP022354.1\|WP_093974719.1\|1073249_1074005_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	1.12473e-15
NZ_CP022354.1\|WP_093974721.1\|1075936_1076599_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.509e-119
NZ_CP022354.1\|WP_023610292.1\|1082377_1083010_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	7.0655e-88
NZ_CP022354.1\|WP_093974723.1\|1086493_1087849_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0

>NZ_CP022354.1|WP_029713988.1|1074400_1075597_+|site-specific-integrase
MKYHKTKYPNIFWYETLKGKRYYIRRSYIFQGKKKEITKSGLKTIPEARAALTEIEKQINEKSIGINMNITVSGYWEIFHEKRVATNRWTPNTEETYKSLMRNNILKEYGTVKLRNLNRNDYEVYIANMLMTKPRESVKCINNCFMAMLNDAVLNGNIPANRLKGVYIGESTVPPKNKKVTMEQFQEWFIKAEQMMDKIFFSLTYLTIFGLRRGEIFGIRQMDIRFHQDGRAILRLHDSRSNHTKNGRHGLKTKESERYVMLDIKGTELLLFLRDNATAIKKRLSIIKDKEWDYISIKEDGNLINPNKLNDEFEKVNEIVGFRVTPHMMRHFFTTQSIIAGVPMEALSKALGHTKMYMTDKYNQVHDELSAQVTDTFSAFLDNNISRLNSPTEGKKAR
>NZ_CP022354.1|WP_093974719.1|1073249_1074005_+|helix-turn-helix-transcriptional-regulator
MNILGNSIKTIRKSKKLTQKDLAKLTGFKQNTISNHENGKRQLDELDIRKYAEALNVAPQDLFDSSKSTPSIPFPNFDPRKAILLSNYSKLNDNRKNRLVSTSETLLAEEQGKITNISEKRSEYGARKRISLSVPGKVSAGTGYWQEDDYDTEVDFYADEIPDEKNYDTVAVVVGHSMEPKIKNGDFLFIKLTDQVGINKIGIFQVNGENYVKKLKNDHLQSLNPKYADITLSESDNFRTVGEIVDIYREG
>NZ_CP022354.1|WP_029713986.1|1072188_1072770_-|hypothetical-protein
MMQEVIQSIVAVGGFGYLNYWIAARVSDIDLGNDQDKKYLIAFLTSLNYTFYLTISLVLRGVVERTIITIVVSILFSLLFPSILKIFYKFINVIRGSSQHSRLEPMLVKNAMFNDDKDRCFIFDFEGNLISSGAMGMLSGKNEELSMKLYPYFASHEEHKIRNEETLYQFLEEKNLEARVYLNFEKKIKIIYF
>NZ_CP022354.1|WP_029713985.1|1071722_1071950_-|hypothetical-protein
MTKKQRLKQQHLKPKKRLREERLKREYSEMYMADLIGLKNRRGYSEKEDGIQSFKDYEMAIIADKFGISEVELFF
>NZ_CP022354.1|WP_029713984.1|1070960_1071680_-|antirepressor
MNEIFNFNGQKVRTLIINNEPYFVGKDVADILGYQNPQKAIRDHVDFDDKLTEQIVQSGQNREMIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPQIRMQGAYVPENLSDEAFIALFTGQKKLKQKQLELAQDVDYLKNEQPIHPSFAQALLKKRKSRVVMWLGGMDSPAYSDKVFAQSVFREAEMDFKAHFNVSRYDMLPKKFEDAALSYWMTWEPSTNTKMKIADLNQSSQLYLM
>NZ_CP022354.1|WP_029713983.1|1070673_1070886_-|hypothetical-protein
MKLEKIEQATKIALSMAVVGTACKIALERHHSHMAYRRKIGEILSAIGPHYVDSELHEFSKFCMSLLKES
>NZ_CP022354.1|WP_029713982.1|1070470_1070677_+|hypothetical-protein
MNKDCEQLIDEIIKDYHEKMYETVPFAELGSFMTKFLLKYKELHPYKKPSVTEIDGVKFFDAGDWEGL
>NZ_CP022354.1|WP_022554795.1|1069956_1070214_-|hypothetical-protein
MDNILMSLSDWIKSIIKDTLNKLVEIENENDNYPELMDISTTSNFLGIGETTFRNQYRYMPDFPKELPAKRWSKRAIKKWLSEQL
>NZ_CP022354.1|WP_029713981.1|1069613_1069802_-|hypothetical-protein
MTENPLSAVIFLIILFLIAFLCRDDSEEQPKSVTKSRDDIVAERYGRVMQIEHHEGSHYGRF
>NZ_CP022354.1|WP_029713980.1|1068280_1069627_-|replicative-DNA-helicase
MEDFKILPHDIQTEQAVLGSIFINPEKIIEVAEYLKPDDFYKPAHRILFKAMLSISSNAEPIDVVTVKSVLESQDNLATIGGITYLLEVVNAVPTSVHAEHYAKIVAKKAQLRSIIDSLSDSIGNAYDENMDIDEIIAKTERSLIEVSQSSNKSSFRPIHDVLAENYQKIEERSNNNTQITGIATGFYDFDKLTTGLHADQLIILAARPAMGKTAFALNIAQNVATKSNKAVAVFSLEMGAESLVERMLASEGTIESHNIRTGQLTVEEWQRLIYVQGELAEAPIFIDDTAGVKITDIRARARRLSQENDGLGLIVVDYLQLIQGSRSDNRQQEVSEISRQLKIIAKELKVPVIALSQLSRSVEQRQDKRPIMSDLRESGSIEQDADIVAFLYRDDYYTDKSDDQPESNLTELIIKKNRHGSLGTVNLYFHKEYTKFSSLKEENNGSA
>NZ_CP022354.1|WP_093974721.1|1075936_1076599_-|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSELKFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLAKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKNMV
>NZ_CP022354.1|WP_002989951.1|1076588_1076930_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>NZ_CP022354.1|WP_032460891.1|1076926_1077796_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVKSQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTLFGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFVYNGKEMYLTNIVSDYTKKVVKALNNEGKGVPEFRI
>NZ_CP022354.1|WP_023080005.1|1077795_1081899_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKLKVLGNTDRHGIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKVDLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPYQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNTSLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDKEMIEERLKKYANLFDDKVMKQLKRRHYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLINDDSLTFKEAIQKAQVSGQGHSLHEQIANLAGSPAIKKGILQTVKIVDELVKVMGHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAKNIIHLFTLTNLGAPAAFKYFDTTIERNRYKSIKEVLDATLIHQSITGLYETRIDLSQLGGD
>NZ_CP022354.1|WP_023610292.1|1082377_1083010_-|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFADFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>NZ_CP022354.1|WP_023079997.1|1083009_1083774_-|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLANQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYETLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_CP022354.1|WP_023080001.1|1083773_1084526_-|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNILVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGCLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQIISDGQLNAQAMIEWRAIKPIESETD
>NZ_CP022354.1|WP_023080002.1|1084535_1085666_-|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFYSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTITNLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_CP022354.1|WP_023080006.1|1085728_1086370_-|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_CP022354.1|WP_093974723.1|1086493_1087849_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKATTAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	MK448795	Streptococcus phage Javan527, complete genome	4413-4442	0	1.0
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	JX409895	Streptococcus phage JX01, complete genome	12808-12837	1	0.967
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	MK448854	Streptococcus phage Javan146, complete genome	5235-5264	1	0.967
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448972	Streptococcus phage Javan520, complete genome	12871-12905	4	0.886
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448763	Streptococcus phage Javan451, complete genome	13649-13683	4	0.886
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448777	Streptococcus phage Javan491, complete genome	13531-13565	4	0.886
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448675	Streptococcus phage Javan129, complete genome	12135-12169	6	0.829
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	NC_018486	Bacillus thuringiensis HD-771 plasmid p01, complete sequence	160696-160725	6	0.8
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	AP013396	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C99-MedDCM-OCT-S44-C25	25274-25303	6	0.8
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	AP013648	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C99-MedDCM-OCT-S33-C45, * SEQUENCING IN PROGRESS *	4096-4125	6	0.8
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448944	Streptococcus phage Javan452, complete genome	12345-12379	7	0.8
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448672	Streptococcus phage Javan117, complete genome	7926-7960	7	0.8
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448849	Streptococcus phage Javan128, complete genome	7830-7864	7	0.8
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448850	Streptococcus phage Javan132, complete genome	12655-12689	7	0.8
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448845	Streptococcus phage Javan118, complete genome	9809-9843	7	0.8
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448673	Streptococcus phage Javan119, complete genome	11431-11465	7	0.8
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448845	Streptococcus phage Javan118, complete genome	14953-14987	7	0.8
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	NC_018501	Bacillus thuringiensis HD-771 plasmid p02, complete sequence	146108-146137	7	0.767
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	NZ_CP008811	Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence	3947-3976	7	0.767
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	NZ_CP053930	Bacillus cereus strain FDAARGOS_797 plasmid unnamed1, complete sequence	3338-3367	7	0.767
NZ_CP022354_4	4.1\|1075769\|30\|NZ_CP022354\|CRISPRCasFinder	1075769-1075798	30	NZ_CP009299	Bacillus cereus D17 plasmid unnamed, complete sequence	174009-174038	7	0.767
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK449010	Streptococcus phage Javan90, complete genome	10515-10549	8	0.771
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448833	Streptococcus phage Javan87, complete genome	10515-10549	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448767	Streptococcus phage Javan467, complete genome	13519-13553	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448685	Streptococcus phage Javan155, complete genome	14540-14574	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448771	Streptococcus phage Javan481, complete genome	13233-13267	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	13624-13658	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448969	Streptococcus phage Javan514, complete genome	14955-14989	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448964	Streptococcus phage Javan502, complete genome	13498-13532	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448943	Streptococcus phage Javan450, complete genome	13519-13553	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448855	Streptococcus phage Javan150, complete genome	14736-14770	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448786	Streptococcus phage Javan509, complete genome	13519-13553	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448774	Streptococcus phage Javan487, complete genome	12069-12103	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448773	Streptococcus phage Javan485, complete genome	14955-14989	8	0.771
NZ_CP022354_3	3.2\|1037270\|35\|NZ_CP022354\|CRISPRCasFinder	1037270-1037304	35	MK448853	Streptococcus phage Javan144, complete genome	14540-14574	8	0.771
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448771	Streptococcus phage Javan481, complete genome	8081-8115	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448973	Streptococcus phage Javan522, complete genome	9986-10020	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448775	Streptococcus phage Javan489, complete genome	11970-12004	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448969	Streptococcus phage Javan514, complete genome	10952-10986	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448794	Streptococcus phage Javan525, complete genome	10165-10199	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448972	Streptococcus phage Javan520, complete genome	8006-8040	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448763	Streptococcus phage Javan451, complete genome	9199-9233	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448774	Streptococcus phage Javan487, complete genome	8066-8100	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448778	Streptococcus phage Javan493, complete genome	10001-10035	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448773	Streptococcus phage Javan485, complete genome	10952-10986	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448958	Streptococcus phage Javan486, complete genome	10306-10340	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448777	Streptococcus phage Javan491, complete genome	8297-8331	9	0.743
NZ_CP022354_3	3.1\|1037204\|35\|NZ_CP022354\|CRISPRCasFinder	1037204-1037238	35	MK448765	Streptococcus phage Javan459, complete genome	10165-10199	9	0.743

1. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 0, identity: 1.0

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
agaaacggcagctaaaaaactaaaaatttc	Protospacer
******************************

2. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 1, identity: 0.967

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
agaaacagcagctaaaaaactaaaaatttc	Protospacer
******.***********************

3. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 1, identity: 0.967

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
agaaacagcagctaaaaaactaaaaatttc	Protospacer
******.***********************

4. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 4, identity: 0.886

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
tcgctggtggttctggactcactcttgatgatctt--	Protospacer
****************************  .*.**

5. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 4, identity: 0.886

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
tcgctggtggttctggactcactcttgatgatctt--	Protospacer
****************************  .*.**

6. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 4, identity: 0.886

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
tcgctggtggttctggactcactcttgatgatctt--	Protospacer
****************************  .*.**

7. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 6, identity: 0.829

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctagtgataatac	Protospacer
**.*************************.*  *.

8. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to NC_018486 (Bacillus thuringiensis HD-771 plasmid p01, complete sequence) position: , mismatch: 6, identity: 0.8

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
cacagcggcagctaaaaaacttaacatttc	Protospacer
 . *.**************** ** *****

9. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to AP013396 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C99-MedDCM-OCT-S44-C25) position: , mismatch: 6, identity: 0.8

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
aaaaactgcagctaaaaaaataaaacaatc	Protospacer
*.**** ************ *****   **

10. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to AP013648 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C99-MedDCM-OCT-S33-C45, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
aaaaactgcagctaaaaaaataaaacaatc	Protospacer
*.**** ************ *****   **

11. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 7, identity: 0.8

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cccgttccagatgttgagatgtctagcgataaaac	Protospacer
**************************.*.*   .

12. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 7, identity: 0.8

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cccgttccagatgttgagatgtctagcgataaaac	Protospacer
**************************.*.*   .

13. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 7, identity: 0.8

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cccgttccagatgttgagatgtctagcgataaaac	Protospacer
**************************.*.*   .

14. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 7, identity: 0.8

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cccgttccagatgttgagatgtctagcgataaaac	Protospacer
**************************.*.*   .

15. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 7, identity: 0.8

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cccgttccagatgttgaaatgtctagcgataatac	Protospacer
*****************.********.*.*  *.

16. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 7, identity: 0.8

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cccgttccagatgttgaaatgtctagcgataatac	Protospacer
*****************.********.*.*  *.

17. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 7, identity: 0.8

tcgctggtggttctggactcactcttgagttttgg----	CRISPR spacer
ttgctggtggttctggtctcactcttga----tgacctc	Protospacer
*.************** ***********    **.

18. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to NC_018501 (Bacillus thuringiensis HD-771 plasmid p02, complete sequence) position: , mismatch: 7, identity: 0.767

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
cactgcggcagctaaaaaacttaacatttc	Protospacer
 .  .**************** ** *****

19. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to NZ_CP008811 (Campylobacter fetus subsp. venerealis 97/608 plasmid pCFV97608-1, complete sequence) position: , mismatch: 7, identity: 0.767

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
aaacagactagctaaaaaactaaaaaattc	Protospacer
*.* * . .***************** ***

20. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to NZ_CP053930 (Bacillus cereus strain FDAARGOS_797 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
cacagctgcagctaaaaaacttaacatttc	Protospacer
 . *.* ************** ** *****

21. spacer 4.1|1075769|30|NZ_CP022354|CRISPRCasFinder matches to NZ_CP009299 (Bacillus cereus D17 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

agaaacggcagctaaaaaactaaaaatttc	CRISPR spacer
cacagctgcagctaaaaaacttaacatttc	Protospacer
 . *.* ************** ** *****

22. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 8, identity: 0.771

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgtaccagatgttgagatgtctagcgataatac	Protospacer
**.** ********************.*.*  *.

23. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 8, identity: 0.771

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgtaccagatgttgagatgtctagcgataatac	Protospacer
**.** ********************.*.*  *.

24. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

25. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttgagttttgg----	CRISPR spacer
ttgctggtggttctggtctgactcttga----tgacctc	Protospacer
*.************** ** ********    **.

26. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

27. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

28. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

29. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

30. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

31. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttgagttttgg----	CRISPR spacer
ttgctggtggttctggtctgactcttga----tgacctc	Protospacer
*.************** ** ********    **.

32. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

33. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

34. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttga--gttttgg	CRISPR spacer
ttgctggtggttccggtctcactcttgatgacctt--	Protospacer
*.***********.** ***********  ...**

35. spacer 3.2|1037270|35|NZ_CP022354|CRISPRCasFinder matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 8, identity: 0.771

tcgctggtggttctggactcactcttgagttttgg----	CRISPR spacer
ttgctggtggttctggtctgactcttga----tgacctc	Protospacer
*.************** ** ********    **.

36. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

37. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

38. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

39. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

40. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

41. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

42. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

43. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

44. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

45. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

46. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

47. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

48. spacer 3.1|1037204|35|NZ_CP022354|CRISPRCasFinder matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 9, identity: 0.743

cccgttccagatgttgagatgtctagtggttttgg	CRISPR spacer
cctgttccagatgttgagatgtctaacgataaaac	Protospacer
**.**********************..*.*   .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36638 : 48952

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032467026.1\|36638_40364_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	7.8e-40	27.0
WP_023080049.1\|40524_41979_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.7e-54	32.9
WP_023080052.1\|42006_43029_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	9.0e-63	41.4
WP_002986700.1\|43196_43751_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_023610065.1\|43934_45482_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	3.4e-45	52.4
WP_002987712.1\|45540_46665_-	CHAP domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_023080273.1\|46917_48183_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_093974496.1\|48460_48952_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.5e-18	40.8

DBSCAN-SWA_2

283098 : 339313

Streptococcus_phage(39.34%)

integrase,holin,portal,tail,tRNA,head,terminase

attL 279608:279623|attR 310061:310076

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
279608:279623	attL	NA	NA	NA	NA
WP_002992279.1\|283098_283797_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_002992278.1\|283798_284224_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_002988178.1\|284213_285242_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.5e-57	40.7
WP_002982921.1\|285412_285682_-	30S ribosomal protein S14	NA	NA	NA	NA
WP_010922646.1\|285917_286661_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_001182060.1\|286900_287680_+	uridine phosphorylase	NA	NA	NA	NA
WP_002992274.1\|287700_288903_+	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_020837734.1\|288932_289604_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_023609903.1\|289698_290868_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	5.5e-16	53.0
WP_011184937.1\|291022_291604_+	DUF536 domain-containing protein	NA	NA	NA	NA
WP_011528955.1\|291613_292240_+	3'-5' exonuclease	A0A0A8WJ41	Clostridium_phage	9.8e-12	28.2
WP_002992265.1\|292391_293129_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_002988205.1\|293185_293485_-	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_012560981.1\|293544_294681_-\|integrase	site-specific integrase	A0A1B1IMP1	Lactococcus_phage	3.7e-57	35.4
WP_050742413.1\|294801_295068_-	hypothetical protein	M1PF81	Streptococcus_phage	9.6e-09	87.1
WP_012767059.1\|295280_295703_-	hypothetical protein	NA	NA	NA	NA
WP_023079223.1\|295713_296097_-	hypothetical protein	A7J268	Streptococcus_phage	9.1e-69	99.2
WP_093974522.1\|296110_296461_-	helix-turn-helix transcriptional regulator	A7J269	Streptococcus_phage	3.1e-39	70.1
WP_093974524.1\|296769_296985_+	transcriptional regulator	M1Q1B4	Streptococcus_phage	2.4e-26	82.6
WP_153277118.1\|296997_297156_+	hypothetical protein	NA	NA	NA	NA
WP_038432530.1\|297157_297571_-	hypothetical protein	NA	NA	NA	NA
WP_002988320.1\|297631_297820_+	helix-turn-helix transcriptional regulator	A0A0B5A7F0	Streptococcus_phage	1.8e-14	65.6
WP_002988323.1\|297852_298581_+	oxidoreductase	Q938N5	Temperate_phage	9.7e-112	81.8
WP_002988329.1\|298758_298959_-	KTSC domain-containing protein	A0A1S5S8T9	Streptococcus_phage	3.3e-22	75.4
WP_038432527.1\|299033_299375_+	hypothetical protein	NA	NA	NA	NA
WP_012560977.1\|299577_299835_+	hypothetical protein	X2KPF2	Streptococcus_phage	3.3e-06	36.8
WP_012560976.1\|299908_300268_+	hypothetical protein	Q9AZZ9	Lactococcus_phage	2.2e-08	50.0
WP_093974526.1\|300699_301017_+	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	1.0e-33	71.4
WP_093974528.1\|301030_301951_+	prephenate dehydrogenase	J7KBV5	Streptococcus_phage	1.3e-116	86.7
WP_093974529.1\|301960_302803_+	ATP-binding protein	A0A1S5S7L9	Streptococcus_phage	1.8e-48	40.3
WP_012560971.1\|302952_303300_+	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	4.6e-11	47.7
WP_093974531.1\|303286_303541_+	hypothetical protein	Q938N0	Temperate_phage	8.8e-36	85.7
WP_093974533.1\|303562_303871_+	hypothetical protein	J7KGX3	Streptococcus_phage	3.9e-46	91.2
WP_093974535.1\|303894_304857_+	recombinase RecT	J7KDK3	Streptococcus_phage	6.9e-158	88.8
WP_093974537.1\|304853_305651_+	hypothetical protein	J7KGZ1	Streptococcus_phage	5.1e-130	83.8
WP_009880272.1\|305927_306326_+	hypothetical protein	A0A286QMU6	Streptococcus_phage	6.6e-30	48.8
WP_093974539.1\|306312_306507_+	hypothetical protein	A3F626	Streptococcus_phage	2.6e-11	91.9
WP_020837669.1\|306503_306917_+	hypothetical protein	Q938M1	Temperate_phage	4.9e-36	65.2
WP_093974540.1\|306913_307198_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.8e-38	90.4
WP_093974542.1\|307200_307743_+	hypothetical protein	A0MN47	Thermus_phage	1.7e-28	38.9
WP_012560962.1\|307746_308232_+	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	3.6e-94	99.4
WP_011054812.1\|308329_308515_+	hypothetical protein	A0A097PBF0	Streptococcus_pyogenes_phage	7.0e-27	100.0
WP_012560961.1\|308511_308805_+	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	8.0e-49	97.9
WP_093974544.1\|308801_309314_+	DUF1642 domain-containing protein	Q938L9	Temperate_phage	7.6e-87	94.7
WP_011017866.1\|309755_310196_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
310061:310076	attR	NA	NA	NA	NA
WP_002990047.1\|311026_311509_+\|terminase	terminase small subunit	E0Y3R8	Staphylococcus_virus	3.3e-15	40.3
WP_002988380.1\|311486_312776_+\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	1.5e-184	74.9
WP_093974546.1\|312787_314287_+\|portal	phage portal protein	C9W9H5	Streptococcus_virus	4.4e-143	54.4
WP_032460167.1\|314267_315893_+\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	6.4e-47	43.3
WP_010922213.1\|315883_316063_+	hypothetical protein	NA	NA	NA	NA
WP_032460166.1\|316122_316389_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	6.2e-32	84.1
WP_032460165.1\|316532_317066_+	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	4.7e-15	84.2
WP_021733109.1\|317075_317444_+	hypothetical protein	A0A0K2CNR0	Brevibacillus_phage	1.6e-06	41.1
WP_032460164.1\|317446_318520_+	hypothetical protein	A0A286QR01	Streptococcus_phage	4.3e-108	57.6
WP_032460163.1\|318529_318772_+	hypothetical protein	NA	NA	NA	NA
WP_032460162.1\|318785_319139_+	phage protein	A0A2H4J002	uncultured_Caudovirales_phage	1.7e-24	50.4
WP_032461956.1\|319135_319444_+	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	4.3e-13	40.2
WP_032467173.1\|319424_319790_+	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	7.7e-17	46.3
WP_011284850.1\|319786_320176_+	hypothetical protein	B5SP36	Lactococcus_phage	4.2e-45	68.2
WP_093974954.1\|320230_320842_+\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	1.0e-42	52.5
WP_002990023.1\|320895_321249_+	hypothetical protein	Q77RZ7	Lactococcus_phage	5.5e-20	48.6
WP_002988428.1\|321290_321620_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	5.7e-11	40.6
WP_093974548.1\|321634_325270_+	tape measure protein	U6E979	Streptococcus_phage	4.0e-04	28.0
WP_011184914.1\|325302_326082_+	hypothetical protein	A3F655	Streptococcus_phage	1.7e-66	54.8
WP_093974549.1\|326078_328130_+	hypothetical protein	A3F656	Streptococcus_phage	0.0e+00	84.7
WP_063632941.1\|328126_329131_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	3.9e-103	60.6
WP_093974551.1\|329146_331057_+	hyaluronidase	Q938J9	Temperate_phage	5.1e-120	71.0
WP_002987333.1\|331070_331232_+	hypothetical protein	NA	NA	NA	NA
WP_012560949.1\|331234_331852_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.0e-74	86.3
WP_002987582.1\|331861_332137_+	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_011017843.1\|332133_332361_+\|holin	phage holin	A7J2B3	Streptococcus_phage	7.6e-31	98.7
WP_093974552.1\|332476_333034_+	glycoside hydrolase family 73 protein	Q938J4	Temperate_phage	9.7e-96	89.2
WP_023079647.1\|334067_334712_+	CHAP domain-containing protein	Q938J4	Temperate_phage	3.6e-94	78.6
WP_011017840.1\|334850_335375_+	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_011888701.1\|335362_336229_+	DUF334 domain-containing protein	Q938J2	Temperate_phage	1.1e-133	99.7
WP_002984424.1\|336985_337792_-	streptodornase Sda3	NA	NA	NA	NA
WP_093974554.1\|338023_338203_+	Paratox	A3F673	Streptococcus_phage	1.4e-16	75.9
WP_002988207.1\|338547_338922_-	helix-turn-helix transcriptional regulator	A0A097BY95	Leuconostoc_phage	2.7e-17	51.6
WP_002988211.1\|339091_339313_+	helix-turn-helix transcriptional regulator	A0A1W6JP54	Staphylococcus_phage	4.8e-06	41.2

DBSCAN-SWA_3

531776 : 596098

Temperate_phage(46.43%)

integrase,holin,portal,tRNA,capsid,terminase

attL 539932:539949|attR 567095:567112

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012560856.1\|531776_532712_+\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	6.0e-05	38.5
WP_023609899.1\|532701_534024_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_002983660.1\|534061_534802_+	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_002994648.1\|534798_536697_+	Stk1 family PASTA domain-containing Ser/Thr kinase	B5LWE2	Feldmannia_species_virus	1.4e-21	30.7
WP_002983667.1\|536768_537512_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_002991890.1\|537508_538513_+	sensor histidine kinase	NA	NA	NA	NA
WP_002983671.1\|538505_539147_+	response regulator transcription factor	NA	NA	NA	NA
WP_011054832.1\|539183_540584_+	Cof-type HAD-IIB family hydrolase	A0A1V0S9I2	Catovirus	4.1e-26	43.5
539932:539949	attL	NA	NA	NA	NA
WP_002991882.1\|540583_540961_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002991877.1\|540978_541920_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.3e-129	77.2
WP_002988970.1\|542047_542680_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	4.2e-63	54.3
WP_002988971.1\|542734_544060_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	2.4e-116	51.1
WP_002993195.1\|544031_544697_+	ComF family protein	NA	NA	NA	NA
WP_002988974.1\|544776_545325_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_011285043.1\|545918_546143_-	hypothetical protein	NA	NA	NA	NA
WP_002983693.1\|553043_553577_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_011285041.1\|553656_554433_-	recombination regulator RecX	NA	NA	NA	NA
WP_011018152.1\|554580_555747_-\|integrase	tyrosine-type recombinase/integrase	C5J953	Streptococcus_phage	2.4e-80	42.4
WP_014635616.1\|555928_557350_-	DUF4041 domain-containing protein	M1PLF9	Streptococcus_phage	1.0e-136	74.1
WP_023605207.1\|557364_557751_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	1.9e-53	77.6
WP_011888679.1\|557734_558076_-	helix-turn-helix transcriptional regulator	J7KJZ4	Streptococcus_phage	1.2e-48	85.8
WP_014635614.1\|558273_558486_+	DNA-binding protein	J7KBP9	Streptococcus_phage	9.2e-31	95.7
WP_011888681.1\|558513_559233_+	oxidoreductase	M1Q1T4	Streptococcus_phage	7.4e-88	70.3
WP_011284879.1\|559330_559570_-	hypothetical protein	NA	NA	NA	NA
WP_011054585.1\|559736_559922_+	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011888682.1\|559992_560244_+	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	2.6e-40	97.6
WP_011017881.1\|560274_560412_+	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
WP_011888683.1\|560505_561222_+	DnaD domain protein	A0A097PBE7	Streptococcus_pyogenes_phage	2.9e-129	93.7
WP_011888684.1\|561208_561991_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	1.0e-143	97.3
WP_011285579.1\|562131_562485_+	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
WP_011018143.1\|562465_562720_+	hypothetical protein	Q938N0	Temperate_phage	3.7e-42	98.8
WP_011018142.1\|562741_563224_+	siphovirus Gp157 family protein	Q938M9	Temperate_phage	8.2e-51	100.0
WP_014635611.1\|563224_563899_+	ERF family protein	Q938M8	Temperate_phage	5.3e-104	97.8
WP_011285575.1\|563891_564317_+	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	2.8e-55	82.3
WP_011106686.1\|564322_564526_+	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_011285574.1\|564525_564966_+	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	4.5e-80	97.9
WP_011284873.1\|564962_565319_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.9e-61	100.0
WP_002995955.1\|565560_565797_+	DUF3310 domain-containing protein	A0A097PAQ7	Streptococcus_pyogenes_phage	2.4e-40	100.0
WP_011284869.1\|565960_566245_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.6e-36	86.2
WP_011888685.1\|566246_566879_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.1e-85	68.6
WP_011888686.1\|566883_567363_+	DUF1642 domain-containing protein	A0A141E0J6	Streptococcus_phage	6.5e-24	41.9
567095:567112	attR	NA	NA	NA	NA
WP_011888687.1\|567813_568248_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	1.7e-71	94.4
WP_010922073.1\|569186_569663_+	hypothetical protein	Q938L4	Temperate_phage	4.9e-48	68.4
WP_010922074.1\|569745_570957_+\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_010922075.1\|570970_572473_+\|portal	phage portal protein	Q938L2	Temperate_phage	5.9e-281	99.6
WP_014635607.1\|572477_573971_+\|capsid	phage capsid protein	Q938L1	Temperate_phage	5.3e-213	79.8
WP_010922077.1\|573970_574198_+	hypothetical protein	NA	NA	NA	NA
WP_011888689.1\|574284_574551_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011888690.1\|574676_575291_+	hypothetical protein	Q938K8	Temperate_phage	3.8e-93	93.1
WP_010922080.1\|575294_576113_+\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_011888692.1\|576166_576583_+	hypothetical protein	Q938K7	Temperate_phage	9.6e-56	98.2
WP_011888693.1\|576572_576905_+	hypothetical protein	Q79S86	Temperate_phage	6.2e-58	99.1
WP_010922083.1\|576904_577261_+	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_011888694.1\|577257_577656_+\|capsid	phage capsid protein	Q79S87	Temperate_phage	6.5e-70	98.5
WP_011018120.1\|577655_578117_+	hypothetical protein	Q938K6	Temperate_phage	1.9e-60	78.8
WP_011888695.1\|578160_578595_+	hypothetical protein	Q938K5	Temperate_phage	4.2e-70	97.9
WP_011888696.1\|578598_579180_+	hypothetical protein	Q938K4	Temperate_phage	1.0e-100	94.3
WP_093974595.1\|579169_582430_+	tape measure protein	Q938K3	Temperate_phage	0.0e+00	99.5
WP_011888697.1\|582426_583143_+	hypothetical protein	Q938K2	Temperate_phage	1.2e-135	99.2
WP_093974597.1\|583139_585281_+	peptidase	Q938K1	Temperate_phage	0.0e+00	95.4
WP_093974599.1\|585280_586300_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	3.3e-174	94.1
WP_002983467.1\|588208_588640_+	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_093974601.1\|588642_589275_+	hypothetical protein	Q938J7	Temperate_phage	4.6e-41	47.6
WP_011184730.1\|589284_589740_+\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	2.3e-63	81.5
WP_093974603.1\|589851_591057_+	CHAP domain-containing protein	A7J2B5	Streptococcus_phage	1.1e-200	82.3
WP_011017840.1\|591196_591721_+	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_011888701.1\|591708_592575_+	DUF334 domain-containing protein	Q938J2	Temperate_phage	1.1e-133	99.7
WP_002984424.1\|593331_594138_-	streptodornase Sda3	NA	NA	NA	NA
WP_011184907.1\|594369_594552_+	hypothetical protein	A3F673	Streptococcus_phage	4.4e-21	83.3
WP_023610126.1\|594742_596098_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	1.5e-73	33.0

DBSCAN-SWA_4

692581 : 732803

Streptococcus_phage(60.87%)

integrase,holin,tail,portal

attL 695178:695197|attR 729345:729364

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002989125.1\|692581_693421_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	7.0e-13	35.7
WP_010922483.1\|693395_694256_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002989129.1\|694233_694821_+	YpmS family protein	NA	NA	NA	NA
WP_002983920.1\|694919_695195_+	DNA-binding protein HU	A7KV42	Bacillus_phage	2.6e-25	73.0
695178:695197	attL	NA	NA	NA	NA
WP_003051793.1\|695284_696427_-\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_010922481.1\|696550_697069_-	restriction endonuclease	E8ZDN5	Streptococcus_phage	9.2e-32	45.9
WP_010922480.1\|697080_697836_-	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.8e-77	60.8
WP_010922479.1\|698037_698250_+	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
WP_010922478.1\|698519_698831_+	excisionase	A0A1S5SA25	Streptococcus_phage	5.3e-43	77.7
WP_023079923.1\|698832_699018_+	hypothetical protein	Q938N3	Temperate_phage	2.6e-21	85.2
WP_021733132.1\|699521_699908_+	DnaD domain-containing protein	Q938N2	Temperate_phage	2.8e-25	55.0
WP_093974631.1\|699888_700122_+	hypothetical protein	Q938N1	Temperate_phage	6.8e-35	93.5
WP_093974633.1\|700118_700259_+	hypothetical protein	NA	NA	NA	NA
WP_093976075.1\|700267_700474_+	hypothetical protein	NA	NA	NA	NA
WP_011017991.1\|700529_700859_+	hypothetical protein	J7KGX3	Streptococcus_phage	1.7e-47	87.2
WP_053308489.1\|700861_701791_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_093974636.1\|701787_702585_+	hypothetical protein	J7KGZ1	Streptococcus_phage	3.7e-141	90.9
WP_093974957.1\|702729_703344_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	1.8e-87	70.1
WP_010922470.1\|703611_704031_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	8.7e-57	79.9
WP_010922469.1\|704139_704484_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	5.5e-41	68.5
WP_002994106.1\|704632_704989_+	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_093974638.1\|704985_706254_+\|portal	phage portal protein	A0A1X9I693	Streptococcus_phage	1.3e-188	75.5
WP_010922467.1\|706246_707740_+	hypothetical protein	M1Q184	Streptococcus_phage	2.0e-87	55.0
WP_002994100.1\|707745_707970_+	hypothetical protein	NA	NA	NA	NA
WP_080464960.1\|707938_708199_+	hypothetical protein	NA	NA	NA	NA
WP_093974640.1\|708191_708458_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	7.3e-33	86.4
WP_010922462.1\|710062_710524_+	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	4.5e-38	53.2
WP_011528788.1\|710548_711460_+	hypothetical protein	M1PFL0	Streptococcus_phage	2.2e-113	67.0
WP_010922460.1\|711459_711660_+	hypothetical protein	NA	NA	NA	NA
WP_011054682.1\|711669_712092_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	8.2e-47	67.2
WP_011054681.1\|712051_712390_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_093974642.1\|712382_712619_+	hypothetical protein	A0A0B5A7G2	Streptococcus_phage	2.1e-20	70.1
WP_093974644.1\|712619_712955_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_093974646.1\|712967_713561_+\|tail	phage tail protein	M1PKG8	Streptococcus_phage	4.5e-59	62.3
WP_010922455.1\|713571_713835_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
WP_011054678.1\|713849_714221_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.7e-35	62.4
WP_093974648.1\|714220_716578_+	hypothetical protein	M1NRG5	Streptococcus_phage	5.0e-141	50.6
WP_010922452.1\|716574_717270_+	hypothetical protein	A0A1B1P761	Bacillus_phage	7.6e-05	29.6
WP_093974650.1\|717266_719225_+	peptidase	M1PKG3	Streptococcus_phage	5.3e-96	49.2
WP_093974653.1\|719224_720334_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.6e-113	66.1
WP_093974655.1\|720348_722133_+	hypothetical protein	Q938J9	Temperate_phage	1.5e-92	46.9
WP_093974657.1\|722144_722573_+	DUF1617 family protein	Q938J8	Temperate_phage	2.4e-62	87.9
WP_093974658.1\|722575_723208_+	hypothetical protein	Q938J7	Temperate_phage	2.3e-40	47.6
WP_002986151.1\|723217_723673_+\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	8.9e-63	80.8
WP_093974660.1\|723784_724993_+	CHAP domain-containing protein	Q938J4	Temperate_phage	9.2e-216	87.6
WP_011017840.1\|725132_725657_+	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_011054729.1\|725644_726511_+	DUF334 domain-containing protein	Q938J2	Temperate_phage	3.7e-134	100.0
WP_011054728.1\|726815_727595_+	streptococcal pyrogenic exotoxin SpeK	Q938J1	Temperate_phage	5.4e-145	100.0
WP_011054727.1\|728070_728646_+	hypothetical protein	Q938J0	Temperate_phage	1.7e-111	100.0
WP_011106694.1\|728639_728927_+	hypothetical protein	Q938I9	Temperate_phage	2.4e-29	100.0
WP_032461122.1\|728992_729175_+	Paratox	A3F673	Streptococcus_phage	1.2e-18	75.0
WP_002994378.1\|729705_731568_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.4e-90	33.8
729345:729364	attR	NA	NA	NA	NA
WP_023610138.1\|731867_732803_-	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	3.0e-65	44.8

DBSCAN-SWA_5

756085 : 815685

Enterococcus_phage(21.43%)

tRNA,protease,integrase,transposase

attL 770881:770940|attR 810855:811727

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002995782.1\|756085_757114_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002995779.1\|757315_758020_+	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_002995774.1\|758138_758855_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_002983995.1\|759150_760113_+	competence protein CoiA	NA	NA	NA	NA
WP_020837346.1\|760125_761931_+	oligoendopeptidase F	NA	NA	NA	NA
WP_093974674.1\|762306_763503_+	OFA family MFS transporter	NA	NA	NA	NA
WP_020837344.1\|763568_764276_+	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	2.6e-08	27.2
WP_020837342.1\|764338_765394_+	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_002995756.1\|765780_768399_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.1e-61	34.1
WP_002989220.1\|768759_768975_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002995753.1\|768971_769733_+	DUF3169 family protein	NA	NA	NA	NA
WP_002995750.1\|769751_770447_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
770881:770940	attL	NA	NA	NA	NA
WP_142402474.1\|771791_773090_-	chloride channel protein	NA	NA	NA	NA
WP_002987365.1\|773079_774039_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	3.7e-127	70.5
WP_093974676.1\|774371_776531_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.6e-263	63.6
WP_002989242.1\|776550_776769_-	redoxin NrdH	A0A249XUR7	Enterococcus_phage	1.1e-13	49.3
WP_093974677.1\|777161_777425_+	phosphocarrier protein HPr	NA	NA	NA	NA
WP_093974679.1\|777429_779160_+	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_011284931.1\|779344_780772_+	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_020837316.1\|780866_782141_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_002989254.1\|782250_783336_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.6e-33	32.3
WP_002984060.1\|783433_784060_+	uridine kinase	A0A1V0SAA3	Catovirus	2.2e-35	39.7
WP_002989257.1\|784139_784403_+	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_093974681.1\|784455_785265_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_009881127.1\|785409_785907_+	GAF domain-containing protein	NA	NA	NA	NA
WP_021733069.1\|785906_787577_+	DNA polymerase III subunit gamma/tau	E7DN81	Pneumococcus_phage	5.1e-47	40.6
WP_012560785.1\|787672_787876_+	DUF3272 domain-containing protein	NA	NA	NA	NA
WP_002984078.1\|787850_788792_-	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor	NA	NA	NA	NA
WP_014635553.1\|788995_791353_+	internalin	NA	NA	NA	NA
WP_002989292.1\|791889_793086_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.5e-138	65.4
WP_002989295.1\|793259_794519_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_038431425.1\|794876_795782_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002984095.1\|796019_796562_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002989302.1\|796570_797854_+	CBS domain-containing protein	NA	NA	NA	NA
WP_002984100.1\|797869_798730_+	methionyl aminopeptidase	NA	NA	NA	NA
WP_093974683.1\|798731_799697_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_011054628.1\|799798_801091_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002984106.1\|801083_801575_+	shikimate kinase	NA	NA	NA	NA
WP_002984109.1\|801782_803234_+	LCP family protein	NA	NA	NA	NA
WP_032466998.1\|803282_804674_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	1.7e-261	98.9
WP_111679872.1\|804941_805154_+	hypothetical protein	NA	NA	NA	NA
WP_023609962.1\|805181_805604_+	nucleoside phosphorylase	F5CA76	Streptococcus_phi-m46.1-like_phage	1.4e-73	96.4
WP_002984115.1\|805688_806090_+	PaaI family thioesterase	NA	NA	NA	NA
WP_002995506.1\|806194_807679_-	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_093974685.1\|808052_809273_+	MFS transporter	NA	NA	NA	NA
WP_011017916.1\|809392_809758_-	thioesterase family protein	NA	NA	NA	NA
WP_011106730.1\|809869_810604_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_136282302.1\|810620_810854_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	1.5e-10	45.7
WP_136127639.1\|810888_811428_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-15	35.5
WP_011284472.1\|811376_811670_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_002984130.1\|811747_813058_-	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
810855:811727	attR	NA	NA	NA	NA
WP_002992869.1\|813281_814154_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_093974958.1\|814453_815685_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.8e-62	48.7

DBSCAN-SWA_6

1017467 : 1159381

156

Streptococcus_phage(78.0%)

integrase,holin,portal,tail,tRNA,protease,head,capsid,terminase

attL 1067021:1067039|attR 1159258:1159276

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003053708.1\|1017467_1018844_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_023610311.1\|1018911_1020321_-	dipeptidase PepV	NA	NA	NA	NA
WP_002989923.1\|1020445_1021048_-	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_011284753.1\|1021231_1023028_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_023610281.1\|1023129_1024527_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_011017728.1\|1024641_1025688_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_002984836.1\|1025681_1026470_-	response regulator transcription factor	NA	NA	NA	NA
WP_023079409.1\|1026473_1028123_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	1.8e-12	33.3
WP_002989931.1\|1028258_1029086_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_002984844.1\|1029082_1029892_-	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_002984845.1\|1029908_1030400_-	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_076634216.1\|1030418_1030844_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_093974698.1\|1031050_1032070_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_014407546.1\|1032199_1032637_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_093974700.1\|1032822_1034505_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_093974701.1\|1034689_1036522_-	elongation factor 4	A0A2K9L2P9	Tupanvirus	2.2e-19	41.0
WP_038432940.1\|1036645_1036792_-	nucleoside-diphosphate kinase	NA	NA	NA	NA
WP_029714017.1\|1037407_1037590_-	hypothetical protein	A3F673	Streptococcus_phage	1.0e-17	71.7
WP_011054450.1\|1037788_1037998_-	helix-turn-helix transcriptional regulator	A3F668	Streptococcus_phage	1.2e-30	100.0
WP_011054448.1\|1038438_1038690_+	hypothetical protein	A3F666	Streptococcus_phage	2.8e-42	96.4
WP_011054447.1\|1038953_1039193_+	hypothetical protein	NA	NA	NA	NA
WP_011054446.1\|1039250_1039607_+	hypothetical protein	NA	NA	NA	NA
WP_029714018.1\|1039722_1040928_-	CHAP domain-containing protein	A7J2B5	Streptococcus_phage	5.0e-198	82.0
WP_029714020.1\|1041050_1041278_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.2e-30	97.3
WP_093974706.1\|1041274_1041547_-	hypothetical protein	A7J2B2	Streptococcus_phage	1.2e-35	89.9
WP_046735270.1\|1041558_1042197_-	hypothetical protein	A3F662	Streptococcus_phage	2.0e-44	52.7
WP_002988448.1\|1042199_1042628_-	DUF1617 family protein	Q938J8	Temperate_phage	8.1e-58	84.3
WP_011017395.1\|1042639_1044544_-	hypothetical protein	Q938J9	Temperate_phage	1.1e-210	83.7
WP_011054440.1\|1045556_1047608_-	hypothetical protein	A3F656	Streptococcus_phage	0.0e+00	85.3
WP_029713951.1\|1047604_1048375_-	hypothetical protein	A3F655	Streptococcus_phage	1.4e-129	87.9
WP_093974708.1\|1048387_1052488_-\|tail	phage tail tape measure protein	A3F654	Streptococcus_phage	0.0e+00	76.3
WP_029713954.1\|1052712_1053015_-	hypothetical protein	A3F652	Streptococcus_phage	2.4e-48	96.0
WP_029713955.1\|1053110_1053695_-\|tail	tail protein	A3F651	Streptococcus_phage	6.2e-93	90.2
WP_029713956.1\|1053706_1054087_-	hypothetical protein	A3F650	Streptococcus_phage	8.2e-62	97.6
WP_011017387.1\|1054079_1054478_-	hypothetical protein	A3F649	Streptococcus_phage	2.9e-70	100.0
WP_029713957.1\|1054479_1054842_-	hypothetical protein	A3F648	Streptococcus_phage	1.6e-59	95.8
WP_029713958.1\|1054834_1055143_-	hypothetical protein	A3F647	Streptococcus_phage	1.4e-43	92.2
WP_093974710.1\|1055326_1056460_-\|capsid	phage major capsid protein	A3F645	Streptococcus_phage	4.6e-201	96.3
WP_029713960.1\|1056476_1057283_-\|protease	Clp protease ClpP	A3F644	Streptococcus_phage	3.9e-146	97.8
WP_027970293.1\|1057263_1058451_-\|portal	phage portal protein	A3F643	Streptococcus_phage	2.1e-220	97.5
WP_093974712.1\|1058631_1060362_-\|terminase	terminase large subunit	A3F641	Streptococcus_phage	0.0e+00	97.2
WP_029713962.1\|1060374_1060692_-\|terminase	terminase	A3F640	Streptococcus_phage	1.3e-49	99.0
WP_093974960.1\|1060834_1061107_-	HNH endonuclease	A3F639	Streptococcus_phage	6.9e-47	95.6
WP_093974962.1\|1061132_1061519_-	hypothetical protein	A3F638	Streptococcus_phage	1.8e-64	92.2
WP_029713966.1\|1061760_1062006_-	hypothetical protein	NA	NA	NA	NA
WP_029713967.1\|1062029_1062326_-	hypothetical protein	NA	NA	NA	NA
WP_029713968.1\|1062480_1063056_-\|integrase	site-specific integrase	A3F636	Streptococcus_phage	2.7e-101	94.8
WP_027970299.1\|1063213_1063615_-	hypothetical protein	A3F635	Streptococcus_phage	3.4e-66	93.2
WP_029713969.1\|1063617_1063962_-	helix-turn-helix transcriptional regulator	A3F633	Streptococcus_phage	1.4e-49	95.0
WP_029713970.1\|1063958_1064237_-	hypothetical protein	A3F632	Streptococcus_phage	9.6e-44	96.7
WP_029713971.1\|1064250_1064643_-	single-stranded DNA-binding protein	A0A1P8VVS8	Streptococcus_phage	5.3e-48	71.7
WP_003057301.1\|1064639_1064861_-	hypothetical protein	NA	NA	NA	NA
WP_029713972.1\|1064853_1065186_-	hypothetical protein	A0A1S5SCX1	Streptococcus_phage	5.9e-32	54.6
WP_029713973.1\|1065178_1065418_-	DUF3310 domain-containing protein	A3F631	Streptococcus_phage	2.6e-37	94.8
WP_093974715.1\|1065540_1065846_-	DUF1372 family protein	A0A1X9I624	Streptococcus_phage	6.0e-23	51.5
WP_093974717.1\|1065842_1066334_-	hypothetical protein	A0A1P8VVP1	Streptococcus_phage	1.2e-70	79.8
WP_153276856.1\|1066320_1066485_-	hypothetical protein	NA	NA	NA	NA
WP_029713977.1\|1066495_1066726_-	hypothetical protein	C5J991	Streptococcus_phage	1.0e-14	52.8
WP_029713978.1\|1066725_1067547_-	ATP-binding protein	A0A1P8VVV9	Streptococcus_phage	1.2e-147	94.9
1067021:1067039	attL	NA	NA	NA	NA
WP_029713979.1\|1067547_1068294_-	DNA replication protein	A0A1P8VVR3	Streptococcus_phage	3.7e-135	97.2
WP_029713980.1\|1068280_1069627_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	2.3e-207	84.0
WP_029713981.1\|1069613_1069802_-	hypothetical protein	NA	NA	NA	NA
WP_022554795.1\|1069956_1070214_-	hypothetical protein	A3F618	Streptococcus_phage	7.0e-41	95.3
WP_029713982.1\|1070470_1070677_+	hypothetical protein	NA	NA	NA	NA
WP_029713983.1\|1070673_1070886_-	hypothetical protein	NA	NA	NA	NA
WP_029713984.1\|1070960_1071680_-	antirepressor	A3F617	Streptococcus_phage	1.6e-106	79.5
WP_029713985.1\|1071722_1071950_-	hypothetical protein	A0A141E1R7	Streptococcus_phage	1.2e-12	57.3
WP_029713986.1\|1072188_1072770_-	hypothetical protein	NA	NA	NA	NA
WP_093974719.1\|1073249_1074005_+	helix-turn-helix transcriptional regulator	M1NS52	Streptococcus_phage	5.6e-78	64.0
WP_029713988.1\|1074400_1075597_+\|integrase	site-specific integrase	A3F610	Streptococcus_phage	1.5e-223	96.7
WP_093974721.1\|1075936_1076599_-	type II-A CRISPR-associated protein Csn2	NA	NA	NA	NA
WP_002989951.1\|1076588_1076930_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_032460891.1\|1076926_1077796_-	type II CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_023080005.1\|1077795_1081899_-	type II CRISPR RNA-guided endonuclease Cas9	NA	NA	NA	NA
WP_023610292.1\|1082377_1083010_-	TIGR01906 family membrane protein	NA	NA	NA	NA
WP_023079997.1\|1083009_1083774_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_023080001.1\|1083773_1084526_-	acyl-[acyl-carrier-protein] thioesterase	NA	NA	NA	NA
WP_023080002.1\|1084535_1085666_-	oxygen-independent coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_023080006.1\|1085728_1086370_-	hypothetical protein	NA	NA	NA	NA
WP_093974723.1\|1086493_1087849_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_011054410.1\|1087902_1088859_-	YbbR-like domain-containing protein	NA	NA	NA	NA
WP_002984858.1\|1088855_1089707_-	TIGR00159 family protein	NA	NA	NA	NA
WP_093974725.1\|1089819_1091157_+	Mur ligase family protein	NA	NA	NA	NA
WP_010922242.1\|1091156_1091948_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_002992006.1\|1092056_1093046_-	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	8.2e-13	25.2
WP_002992004.1\|1093278_1095696_+	polysaccharide lyase 8 family protein	NA	NA	NA	NA
WP_002989978.1\|1096368_1098132_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.2e-33	25.5
WP_011284736.1\|1098164_1098452_+	hypothetical protein	NA	NA	NA	NA
WP_011054406.1\|1098462_1099872_-	dihydrolipoamide acetyltransferase	NA	NA	NA	NA
WP_002989981.1\|1100056_1101055_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_002989983.1\|1101113_1102082_-	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
WP_023609858.1\|1102366_1104274_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.2e-55	31.2
WP_002991984.1\|1104318_1104645_-	hypothetical protein	NA	NA	NA	NA
WP_002991981.1\|1104674_1105460_-	esterase family protein	NA	NA	NA	NA
WP_002991979.1\|1105592_1107254_-	ribonuclease J	NA	NA	NA	NA
WP_002991977.1\|1107457_1108216_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	7.7e-11	28.0
WP_002991975.1\|1108212_1109082_-	ABC transporter permease	NA	NA	NA	NA
WP_145976943.1\|1109257_1109368_-	hypothetical protein	NA	NA	NA	NA
WP_032462946.1\|1109426_1110425_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_093974729.1\|1110778_1112431_+	PavA family fibronectin-binding protein Fbp54	M1I0S4	Acanthocystis_turfacea_Chlorella_virus	1.7e-07	35.1
WP_030126713.1\|1112489_1113737_-	hypothetical protein	NA	NA	NA	NA
WP_002990002.1\|1113726_1114908_-	AI-2E family transporter	NA	NA	NA	NA
WP_002984880.1\|1114965_1115442_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_080286815.1\|1116782_1117460_-	streptococcal pyrogenic exotoxin SpeI	A0A075M4C7	Staphylococcus_phage	1.2e-26	32.0
WP_015898599.1\|1117733_1119068_-	lysin	Q5MY96	Streptococcus_phage	5.9e-248	93.2
WP_011054731.1\|1119179_1119365_-	hypothetical protein	Q938J5	Temperate_phage	1.7e-25	100.0
WP_023078532.1\|1119361_1119658_-	hypothetical protein	Q938J6	Temperate_phage	2.9e-46	99.0
WP_093974731.1\|1119668_1120280_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	2.8e-80	88.2
WP_093974733.1\|1120282_1120711_-	DUF1617 family protein	A3F661	Streptococcus_phage	1.6e-66	92.9
WP_093974734.1\|1120719_1122741_-	hyaluronidase	Q938J9	Temperate_phage	1.7e-161	67.3
WP_093974964.1\|1122750_1123818_-	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	2.0e-118	72.4
WP_038433248.1\|1123859_1125842_-	peptidase	A7J2A7	Streptococcus_phage	0.0e+00	93.9
WP_011054865.1\|1125851_1126694_-	hypothetical protein	A7J2A6	Streptococcus_phage	8.8e-157	97.9
WP_093974736.1\|1126705_1131088_-	tape measure protein	A7J2A5	Streptococcus_phage	2.4e-221	75.6
WP_011888930.1\|1131102_1131336_-	hypothetical protein	A7J2A4	Streptococcus_phage	1.3e-33	98.7
WP_011888931.1\|1131410_1131866_-	hypothetical protein	A7J2A3	Streptococcus_phage	5.3e-76	99.3
WP_011054869.1\|1131919_1132519_-\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	1.7e-90	97.1
WP_011054870.1\|1132530_1132890_-	hypothetical protein	A7J2A1	Streptococcus_phage	1.2e-57	98.3
WP_011106640.1\|1132893_1133238_-	hypothetical protein	A7J2A0	Streptococcus_phage	5.1e-55	98.2
WP_011054872.1\|1133234_1133513_-	hypothetical protein	A7J299	Streptococcus_phage	1.9e-47	100.0
WP_011054873.1\|1133523_1133880_-\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	4.6e-59	100.0
WP_093974738.1\|1133891_1134779_-\|capsid	phage capsid protein	A7J297	Streptococcus_phage	6.2e-161	99.7
WP_011888933.1\|1134791_1135361_-	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	1.9e-83	100.0
WP_011888934.1\|1135528_1135795_-	hypothetical protein	Q938K9	Temperate_phage	2.9e-37	96.6
WP_011054876.1\|1135799_1135988_-	hypothetical protein	A7J294	Streptococcus_phage	7.4e-24	100.0
WP_093974740.1\|1136015_1137464_-\|head	phage head morphogenesis protein	A7J293	Streptococcus_phage	1.7e-277	99.4
WP_038433243.1\|1137423_1138956_-\|portal	phage portal protein	A7J292	Streptococcus_phage	4.5e-292	99.8
WP_038433241.1\|1138971_1140249_-\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	3.1e-246	99.8
WP_011106637.1\|1140238_1140691_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	6.9e-76	100.0
WP_002988747.1\|1140780_1141197_-	DUF722 domain-containing protein	A7J289	Streptococcus_phage	6.6e-73	100.0
WP_015898610.1\|1141193_1141910_-	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	9.1e-30	52.2
WP_011888761.1\|1141906_1142200_-	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	3.0e-48	97.9
WP_015898611.1\|1142196_1142382_-	hypothetical protein	A0A097PBF0	Streptococcus_pyogenes_phage	7.8e-26	96.7
WP_015898612.1\|1142406_1142634_-	hypothetical protein	A3F630	Streptococcus_phage	5.1e-27	80.0
WP_093974741.1\|1142803_1144126_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	1.3e-250	97.3
WP_015898615.1\|1144122_1144398_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	7.7e-46	97.8
WP_093974743.1\|1144784_1147169_-	DNA primase	A7J282	Streptococcus_phage	1.4e-276	94.6
WP_093974744.1\|1147173_1149096_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	97.7
WP_086934854.1\|1149138_1149702_-	DUF2815 family protein	D2J040	Enterococcus_phage	3.3e-51	58.5
WP_011888943.1\|1149710_1150868_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.0e-216	98.2
WP_002988708.1\|1150867_1151167_-	hypothetical protein	A7J277	Streptococcus_phage	1.8e-43	100.0
WP_002983407.1\|1151254_1151458_-	hypothetical protein	A7J276	Streptococcus_phage	9.4e-33	100.0
WP_093974746.1\|1151602_1151989_-	hypothetical protein	A7J274	Streptococcus_phage	3.1e-56	87.4
WP_000049475.1\|1151985_1152189_-	hypothetical protein	NA	NA	NA	NA
WP_011888947.1\|1152181_1152352_-	hypothetical protein	A7J273	Streptococcus_phage	1.2e-20	89.3
WP_015898619.1\|1152353_1152665_-	hypothetical protein	A1EAC3	Streptococcus_phage	6.9e-51	89.3
WP_001112862.1\|1152745_1152937_-	hypothetical protein	A0A141DZR9	Streptococcus_phage	4.7e-18	69.8
WP_093974748.1\|1152987_1153776_+	hypothetical protein	NA	NA	NA	NA
WP_015898620.1\|1153726_1153972_-	hypothetical protein	X2L066	Streptococcus_phage	7.4e-08	55.8
WP_093974750.1\|1154267_1154618_+	helix-turn-helix transcriptional regulator	A0A1S5SAD3	Streptococcus_phage	2.1e-35	65.2
WP_093974752.1\|1154620_1155007_+	ImmA/IrrE family metallo-endopeptidase	M1PFJ2	Streptococcus_phage	3.0e-35	56.2
WP_093974754.1\|1155018_1155285_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_011888953.1\|1155412_1156552_+\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	1.2e-119	56.3
WP_014635423.1\|1156634_1157675_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	5.5e-68	43.6
WP_002990099.1\|1157918_1158512_-	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.7e-08	28.2
WP_014407521.1\|1158511_1159381_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	5.4e-101	64.2
1159258:1159276	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1265757 : 1273157

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002992646.1\|1265757_1267110_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	23.8
WP_002992643.1\|1267330_1267672_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	41.1
WP_002992640.1\|1267732_1268899_-	chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	32.8
WP_002985140.1\|1268992_1269679_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_023609837.1\|1269675_1270839_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	7.6e-143	64.9
WP_050580611.1\|1270946_1273157_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.9e-268	69.2

DBSCAN-SWA_8

1465582 : 1499037

Bacillus_phage(25.0%)

tRNA,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985672.1\|1465582_1467526_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.0e-120	38.7
WP_002994187.1\|1467947_1469282_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_002994184.1\|1469283_1470282_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_002985680.1\|1470412_1471414_-	catabolite control protein A	C6ZCU4	Enterobacteria_phage	6.1e-24	28.5
WP_023609946.1\|1471587_1472673_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_002985684.1\|1472721_1473387_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_002985686.1\|1473397_1473775_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_002994177.1\|1473919_1474846_+	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	2.6e-77	47.5
WP_002994173.1\|1475056_1475740_+	DUF969 domain-containing protein	NA	NA	NA	NA
WP_002985692.1\|1475739_1476666_+	DUF979 domain-containing protein	NA	NA	NA	NA
WP_002994169.1\|1476715_1477363_+	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_010921981.1\|1477479_1478199_-	glutaminyl-peptide cyclotransferase	NA	NA	NA	NA
WP_002994152.1\|1478204_1478672_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	5.7e-41	57.0
WP_076707645.1\|1478674_1481008_-	ribonuclease R	Q0GXV6	Lactococcus_phage	8.8e-90	39.8
WP_002985700.1\|1481101_1481338_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_002990729.1\|1481383_1481530_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_002994146.1\|1481526_1482720_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_002994144.1\|1482841_1484344_-	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	6.7e-75	41.2
WP_002994141.1\|1484533_1485127_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_093974807.1\|1485123_1485951_-	DNA-formamidopyrimidine glycosylase	A0A127AWE5	Bacillus_phage	3.0e-16	27.5
WP_002990747.1\|1486122_1486989_-	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_128650799.1\|1487077_1487146_+	peptide pheromone SHP2	NA	NA	NA	NA
WP_011285423.1\|1487295_1487538_+	hypothetical protein	NA	NA	NA	NA
WP_020833327.1\|1488059_1488329_+	quorum-sensing system protein StcA	NA	NA	NA	NA
WP_093974969.1\|1488676_1489123_-	histidine kinase	NA	NA	NA	NA
WP_032462998.1\|1489167_1490238_-	hypothetical protein	NA	NA	NA	NA
WP_032467019.1\|1490488_1490890_-	hypothetical protein	NA	NA	NA	NA
WP_011054252.1\|1491083_1491365_-	hypothetical protein	NA	NA	NA	NA
WP_028797130.1\|1491414_1491579_-	hypothetical protein	NA	NA	NA	NA
WP_003060803.1\|1491903_1492104_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_012560514.1\|1492116_1492344_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002987564.1\|1493538_1493721_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002994504.1\|1493735_1493981_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_020833322.1\|1495306_1497460_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	5.7e-43	28.3
WP_014635340.1\|1497470_1498835_+\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_011017462.1\|1498911_1499037_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_9

1503211 : 1563958

Streptococcus_phage(30.0%)

tRNA,protease,transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002987929.1\|1503211_1503427_-\|transposase	transposase	U5P429	Shigella_phage	7.0e-10	45.5
WP_111694349.1\|1503581_1504037_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.4e-14	34.8
WP_020833317.1\|1504069_1504351_-\|transposase	transposase	NA	NA	NA	NA
WP_002994587.1\|1504416_1504734_-	hypothetical protein	NA	NA	NA	NA
WP_028797129.1\|1504782_1505010_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_072135613.1\|1505620_1505983_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002994580.1\|1506380_1506605_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_002994577.1\|1506902_1507139_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_011528336.1\|1507243_1507954_+\|bacteriocin	bacteriocin ABC transporter	NA	NA	NA	NA
WP_014635333.1\|1508176_1508623_+	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	4.1e-12	36.0
WP_014407373.1\|1509224_1509479_+	hypothetical protein	NA	NA	NA	NA
WP_093974809.1\|1509784_1510261_-	NUDIX hydrolase	NA	NA	NA	NA
WP_002985743.1\|1510280_1511177_-	GTPase Era	NA	NA	NA	NA
WP_002985746.1\|1511296_1511704_-	diacylglycerol kinase	NA	NA	NA	NA
WP_032467023.1\|1511684_1512182_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_009880369.1\|1512340_1512916_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_002990786.1\|1512961_1514014_-	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_093974811.1\|1514172_1515945_-	oleate hydratase	NA	NA	NA	NA
WP_093974813.1\|1516258_1517440_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.6e-16	40.5
WP_002985757.1\|1517595_1517811_-	YozE family protein	NA	NA	NA	NA
WP_002990794.1\|1517807_1518317_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_038433941.1\|1518389_1519247_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002985763.1\|1519355_1519913_-	ribosome recycling factor	NA	NA	NA	NA
WP_002985765.1\|1519941_1520670_-	UMP kinase	NA	NA	NA	NA
WP_002985768.1\|1520992_1521682_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002990800.1\|1521787_1522213_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_010921962.1\|1522456_1522810_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_093974815.1\|1522879_1525285_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	2.9e-88	50.5
WP_038432840.1\|1525501_1526308_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_011017448.1\|1526455_1527310_-	metal ABC transporter permease	NA	NA	NA	NA
WP_038432839.1\|1527310_1528036_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.8e-17	32.6
WP_004218965.1\|1528099_1529032_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_063632608.1\|1529177_1529825_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_093974817.1\|1529923_1530265_-	hypothetical protein	NA	NA	NA	NA
WP_010921957.1\|1530415_1531111_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_023078625.1\|1531130_1531382_-	hypothetical protein	NA	NA	NA	NA
WP_093974819.1\|1531381_1531936_-	NUDIX hydrolase	NA	NA	NA	NA
WP_093974821.1\|1531966_1533349_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	8.5e-32	36.0
WP_002993065.1\|1533521_1534859_-	MFS transporter	NA	NA	NA	NA
WP_093974823.1\|1535191_1536151_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_011054234.1\|1536226_1536925_-	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	9.3e-11	25.2
WP_093974825.1\|1536917_1537154_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_093974826.1\|1537513_1538179_+	hypothetical protein	NA	NA	NA	NA
WP_010921949.1\|1538425_1539124_+	streptococcal pyrogenic exotoxin SpeJ	NA	NA	NA	NA
WP_002993880.1\|1539437_1539758_-	hypothetical protein	NA	NA	NA	NA
WP_011017435.1\|1541161_1541413_-	hypothetical protein	NA	NA	NA	NA
WP_093974828.1\|1541603_1542035_-	hypothetical protein	NA	NA	NA	NA
WP_093974830.1\|1542476_1543229_+	ADP-ribosyltransferase	NA	NA	NA	NA
WP_063631771.1\|1543433_1545614_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.3e-171	43.3
WP_023610055.1\|1545580_1546069_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_012560480.1\|1546072_1547086_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	4.2e-97	53.4
WP_093974832.1\|1547580_1549581_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	1.2e-87	35.3
WP_031488577.1\|1549820_1550528_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_093974834.1\|1550630_1550810_-	hypothetical protein	NA	NA	NA	NA
WP_093974836.1\|1551300_1556244_-\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_011527483.1\|1556508_1557696_-	L-lactate oxidase	NA	NA	NA	NA
WP_021340916.1\|1557923_1558751_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	79.9
WP_093974838.1\|1558824_1559181_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	3.1e-39	64.1
WP_011528296.1\|1559480_1560110_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_023609786.1\|1560156_1560549_-	hypothetical protein	NA	NA	NA	NA
WP_023609789.1\|1560575_1561439_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	5.5e-114	74.3
WP_002985838.1\|1561443_1561767_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_020833285.1\|1562171_1562411_-	tpl protein	NA	NA	NA	NA
WP_093974840.1\|1562429_1563305_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.3e-65	44.5
WP_010921930.1\|1563322_1563958_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022354

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection