CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022527	Neisseria sp. KEM232 chromosome, complete genome	6 crisprs	cas1,cas4,cas7,cas8c,cas5,cas3,DEDDh,DinG,csa3,WYL	0	10	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022527_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022527_1

175428-177115

TypeI

Consensus_repeat	Method
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CRT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CRISPRCasFinder
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	PILER-CR

25 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP022527_1

>merge|NZ_CP022527|1|175428-177115|CRT,CRISPRCasFinder,PILER-CR
TTTCAACATAACAACTGCTTGAAGGCAGCTGCCACAACCACCACCCACCGCCGCAAAAAGCATTGCTTTTCAACACACAGCCGCCCGAATGCGGCTGCCCGACGACTTTGCCCGCCTAAACATCGACGGCCGCGTTTCAACACACAGCCGCCCGAAGGCGGCTGCACAAAAGCGTCTACGGCCTCTACAAATCGGCCGAAGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGACGGCAGACCGATATTGGTTGCCGCGTACTACGGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCCGTCTGCATCGACGGCGTAGCCGCCGAGATGTGCGGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCAACCGTCTGCCGCAGCACGCAAGCCCGTTGCGGTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCATCTCGTCAGATGCCCCGAGATTGTCCGGACCGATGTTTCAACACTCAGCAGCCCGAAGGCGGCTGCGGTTTTGAGCCACAGGGTGCGGTTGGCCAGCGCCTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCAAAAAACCGTTTTGCACTTGGGCGGCGTGGGGCAGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGCTAACGCCGTACCGTCCCAATCAGACGGCTGATGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCTACCGCCAATTCGTGGCCGACAACGCCGCCGCGATGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGACGGTGGACGGACACGCCGCCGGCGAAGGGGACGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCAAAAACTGCGAGGCCAACGTCCTCAACAACAACGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGCCGAGCAGCCAACGCCCTTTGTCTGTCCACGGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGTACTGGCCGACGGCAACACCGCACCGTACACCTTTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGGATTGTAACGTCAAACTGAAGCGGGCTTCGGATGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGCATGGCGGATGCCGACGTGTTCAACACCTGCCTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCTGTACTTGGTCGTCTGGCCGCCCTCTTCAAATTTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCCAGGTTTCGGTTTATCGCACCCCCGATGAAAATAGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGAAGGCTCGGTCTTGATAGTTGACGAAGCATCTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCCGCCTCAAAAGCCGTATCGGGTGTGATTTCGTTGTTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGCCCGTCAGCTGCATGGCCGCCGAAGTGACATTGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCGTCTTAATGTGCTTGGTCGAACTGTGATAAAGGTCGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCCGTCCCCGAACGCGAGCGGCAGGCCGTACCGTCGGTTTCAACACTCAGCCGCCCGAAGGCGGCTGCCGCGTAGCCCTAAGGGGCGTGGCGAACGAGATGGGTTTCAACACTCAGCCGCCCGAAGGCGGCTGC

>NZ_CP022527|1|1|175428-177115|CRT
TTTCAACATAACAACTGCTTGAAGGCAGCTGC	CACAACCACCACCCACCGCCGCAAAAAGCATTGC
TTTTCAACACACAGCCGCCCGAATGCGGCTGC	CCGACGACTTTGCCCGCCTAAACATCGACGGCCGC
GTTTCAACACACAGCCGCCCGAAGGCGGCTGC	ACAAAAGCGTCTACGGCCTCTACAAATCGGCCGAA
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GACGGCAGACCGATATTGGTTGCCGCGTACTACG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGTCTGCATCGACGGCGTAGCCGCCGAGATGTGCG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	AACCGTCTGCCGCAGCACGCAAGCCCGTTGCGGT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	ATCTCGTCAGATGCCCCGAGATTGTCCGGACCGAT
GTTTCAACACTCAGCAGCCCGAAGGCGGCTGC	GGTTTTGAGCCACAGGGTGCGGTTGGCCAGCGCCT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	AAAAAACCGTTTTGCACTTGGGCGGCGTGGGGCA
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCTAACGCCGTACCGTCCCAATCAGACGGCTGAT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	TACCGCCAATTCGTGGCCGACAACGCCGCCGCGAT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GACGGTGGACGGACACGCCGCCGGCGAAGGGGAC
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	AAAAACTGCGAGGCCAACGTCCTCAACAACAAC
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCCGAGCAGCCAACGCCCTTTGTCTGTCCACG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GTACTGGCCGACGGCAACACCGCACCGTACACCTTT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GGATTGTAACGTCAAACTGAAGCGGGCTTCGGAT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCATGGCGGATGCCGACGTGTTCAACACCTGCCT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	TGTACTTGGTCGTCTGGCCGCCCTCTTCAAATTT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CAGGTTTCGGTTTATCGCACCCCCGATGAAAATA
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GAAGGCTCGGTCTTGATAGTTGACGAAGCATCT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGCCTCAAAAGCCGTATCGGGTGTGATTTCGTTGTT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCCCGTCAGCTGCATGGCCGCCGAAGTGACATT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GTCTTAATGTGCTTGGTCGAACTGTGATAAAGGTC
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGTCCCCGAACGCGAGCGGCAGGCCGTACCGTCG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGCGTAGCCCTAAGGGGCGTGGCGAACGAGATGG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC

>NZ_CP022527|1|1|175494-177115|CRISPRCasFinder
TTTTCAACACACAGCCGCCCGAATGCGGCTGC	CCGACGACTTTGCCCGCCTAAACATCGACGGCCGC
GTTTCAACACACAGCCGCCCGAAGGCGGCTGC	ACAAAAGCGTCTACGGCCTCTACAAATCGGCCGAA
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GACGGCAGACCGATATTGGTTGCCGCGTACTACG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGTCTGCATCGACGGCGTAGCCGCCGAGATGTGCG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	AACCGTCTGCCGCAGCACGCAAGCCCGTTGCGGT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	ATCTCGTCAGATGCCCCGAGATTGTCCGGACCGAT
GTTTCAACACTCAGCAGCCCGAAGGCGGCTGC	GGTTTTGAGCCACAGGGTGCGGTTGGCCAGCGCCT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	AAAAAACCGTTTTGCACTTGGGCGGCGTGGGGCA
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCTAACGCCGTACCGTCCCAATCAGACGGCTGAT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	TACCGCCAATTCGTGGCCGACAACGCCGCCGCGAT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GACGGTGGACGGACACGCCGCCGGCGAAGGGGAC
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	AAAAACTGCGAGGCCAACGTCCTCAACAACAAC
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCCGAGCAGCCAACGCCCTTTGTCTGTCCACG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GTACTGGCCGACGGCAACACCGCACCGTACACCTTT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GGATTGTAACGTCAAACTGAAGCGGGCTTCGGAT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCATGGCGGATGCCGACGTGTTCAACACCTGCCT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	TGTACTTGGTCGTCTGGCCGCCCTCTTCAAATTT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CAGGTTTCGGTTTATCGCACCCCCGATGAAAATA
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GAAGGCTCGGTCTTGATAGTTGACGAAGCATCT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGCCTCAAAAGCCGTATCGGGTGTGATTTCGTTGTT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GCCCGTCAGCTGCATGGCCGCCGAAGTGACATT
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	GTCTTAATGTGCTTGGTCGAACTGTGATAAAGGTC
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGTCCCCGAACGCGAGCGGCAGGCCGTACCGTCG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC	CGCGTAGCCCTAAGGGGCGTGGCGAACGAGATGG
GTTTCAACACTCAGCCGCCCGAAGGCGGCTGC

>NZ_CP022527|1|1|175495-177115|PILER-CR
TTTCAACACACAGCCGCCCGAATGCGGCTGCC	CGACGACTTTGCCCGCCTAAACATCGACGGCCGCG
TTTCAACACACAGCCGCCCGAAGGCGGCTGCA	CAAAAGCGTCTACGGCCTCTACAAATCGGCCGAAG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	ACGGCAGACCGATATTGGTTGCCGCGTACTACGG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCC	GTCTGCATCGACGGCGTAGCCGCCGAGATGTGCGG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCA	ACCGTCTGCCGCAGCACGCAAGCCCGTTGCGGTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCA	TCTCGTCAGATGCCCCGAGATTGTCCGGACCGATG
TTTCAACACTCAGCAGCCCGAAGGCGGCTGCG	GTTTTGAGCCACAGGGTGCGGTTGGCCAGCGCCTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCA	AAAAACCGTTTTGCACTTGGGCGGCGTGGGGCAG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	CTAACGCCGTACCGTCCCAATCAGACGGCTGATG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCT	ACCGCCAATTCGTGGCCGACAACGCCGCCGCGATG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	ACGGTGGACGGACACGCCGCCGGCGAAGGGGACG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCA	AAAACTGCGAGGCCAACGTCCTCAACAACAACG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	CCGAGCAGCCAACGCCCTTTGTCTGTCCACGG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	TACTGGCCGACGGCAACACCGCACCGTACACCTTTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	GATTGTAACGTCAAACTGAAGCGGGCTTCGGATG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	CATGGCGGATGCCGACGTGTTCAACACCTGCCTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCT	GTACTTGGTCGTCTGGCCGCCCTCTTCAAATTTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCC	AGGTTTCGGTTTATCGCACCCCCGATGAAAATAG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	AAGGCTCGGTCTTGATAGTTGACGAAGCATCTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCC	GCCTCAAAAGCCGTATCGGGTGTGATTTCGTTGTTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	CCCGTCAGCTGCATGGCCGCCGAAGTGACATTG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCG	TCTTAATGTGCTTGGTCGAACTGTGATAAAGGTCG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCC	GTCCCCGAACGCGAGCGGCAGGCCGTACCGTCGG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGCC	GCGTAGCCCTAAGGGGCGTGGCGAACGAGATGGG
TTTCAACACTCAGCCGCCCGAAGGCGGCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022527.1\|WP_009427627.1\|179674_180544_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP022527.1\|WP_009427641.1\|169965_171846_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NZ_CP022527.1\|WP_009427636.1\|174769_175312_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_094030830.1\|172095_173007_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP022527.1\|WP_009426521.1\|164412_165549_+\|phospholipase-A	unknown	unknown	gnl\|CDD\|376748
NZ_CP022527.1\|WP_009427625.1\|182620_183355_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NZ_CP022527.1\|WP_009427626.1\|180572_182624_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP022527.1\|WP_009427629.1\|177640_178654_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP022527.1\|WP_094030832.1\|183372_185856_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP022527.1\|WP_009426524.1\|166612_167101_+\|inhibitor-of-vertebrate-lysozyme	unknown	unknown	gnl\|CDD\|370137
NZ_CP022527.1\|WP_009427628.1\|178998_179673_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
NZ_CP022527.1\|WP_009427623.1\|186097_187495_+\|ATP-dependent-RNA-helicase-HrpA	unknown	unknown	gnl\|CDD\|182986
NZ_CP022527.1\|WP_094030831.1\|172990_173932_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP022527.1\|WP_009427637.1\|174250_174706_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_094030833.1\|188781_189543_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180993
NZ_CP022527.1\|WP_009427622.1\|187570_188395_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP022527.1\|WP_009426523.1\|165762_166470_+\|DUF502-domain-containing-protein	unknown	unknown	gnl\|CDD\|225480
NZ_CP022527.1\|WP_009427642.1\|167410_169384_-\|transglutaminase-domain-containing-protein	unknown	unknown	gnl\|CDD\|378784
NZ_CP022527.1\|WP_009427630.1\|177304_177598_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP022527.1\|WP_157697471.1\|171938_172082_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022527.1\|WP_009427627.1\|179674_180544_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	2.95492e-110
NZ_CP022527.1\|WP_009427641.1\|169965_171846_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NZ_CP022527.1\|WP_094030830.1\|172095_173007_+\|AAA-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.53667e-84
NZ_CP022527.1\|WP_009426521.1\|164412_165549_+\|phospholipase-A	gnl\|CDD\|376748	pfam02253, PLA1, Phospholipase A1. Phospholipase A1 is a bacterial outer membrane bound acyl hydrolase with a broad substrate specificity EC:3.1.1.32. It has been proposed that Ser164 is the active site for Escherichia coli phospholipase A1.	7.48623e-127
NZ_CP022527.1\|WP_009427625.1\|182620_183355_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.82828e-89
NZ_CP022527.1\|WP_009427626.1\|180572_182624_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	2.71002e-131
NZ_CP022527.1\|WP_009427629.1\|177640_178654_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP022527.1\|WP_094030832.1\|183372_185856_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.40339e-54
NZ_CP022527.1\|WP_009426524.1\|166612_167101_+\|inhibitor-of-vertebrate-lysozyme	gnl\|CDD\|370137	pfam08816, Ivy, Inhibitor of vertebrate lysozyme (Ivy). This bacterial family is a strong inhibitor of vertebrate lysozyme.	2.20884e-15
NZ_CP022527.1\|WP_009427628.1\|178998_179673_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.24192e-43
NZ_CP022527.1\|WP_009427623.1\|186097_187495_+\|ATP-dependent-RNA-helicase-HrpA	gnl\|CDD\|182986	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional.	0
NZ_CP022527.1\|WP_094030831.1\|172990_173932_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	2.26417e-17
NZ_CP022527.1\|WP_094030833.1\|188781_189543_+\|SDR-family-oxidoreductase	gnl\|CDD\|180993	PRK07478, PRK07478, short chain dehydrogenase; Provisional.	5.29858e-101
NZ_CP022527.1\|WP_009427622.1\|187570_188395_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	7.05005e-05
NZ_CP022527.1\|WP_009426523.1\|165762_166470_+\|DUF502-domain-containing-protein	gnl\|CDD\|225480	COG2928, COG2928, Uncharacterized conserved protein [Function unknown].	3.59222e-83
NZ_CP022527.1\|WP_009427642.1\|167410_169384_-\|transglutaminase-domain-containing-protein	gnl\|CDD\|378784	pfam11992, DUF3488, Domain of unknown function (DUF3488). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is typically between 323 to 339 amino acids in length. This domain is found associated with pfam01841. This domain has a conserved PLW sequence motif. This domain contains 6 transmembrane helices.	2.31748e-65
NZ_CP022527.1\|WP_009427630.1\|177304_177598_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.60848e-33

>NZ_CP022527.1|WP_009427636.1|174769_175312_+|hypothetical-protein
MKKPMDFAQTNLLLEQYINGTLQKYDLLFCLFGGNGREVPPQERSRFLLEYLHRVTETQNGGGAEYAVILHEVLSCKDPQTLAAFQKLLAQDWHERHEDIVTLLAECPSESSLPHLVKAFAFDPPYADRYPLQKKIMWAVYRIAAGGRRGAEILQPLAKSAAPELQKEFRQFASNIVAKP
>NZ_CP022527.1|WP_009427637.1|174250_174706_+|hypothetical-protein
MSVDTPKFPRSYRLFAQRYGWGRTLGNFLIYLPADAACDSWQQMREAVKSAYLDDLADYADYYPDDIVQLMARTEPFARSESGFFLFWDTASGAGRDEFDIYATDFVGGFHLLGSDLPEMFRNLTRHGSVLQACFNREPFPNTFEGFDGIA
>NZ_CP022527.1|WP_094030831.1|172990_173932_+|DUF58-domain-containing-protein
MWPFSKPVQAASVSRSPTLAAIRCRPTRPGVGLLAVVGLLWLVGVNYQVNLAYVAAFWLFGFLMVGVLLNLRQLLALQIDVAMPQEVFAGQNAVLRLTADHGGRSRFLWLCSEDDYLAQSPSENIWQPWRIGKSGGAYEWRIPALLRGRLRVPPLRTASVAPFGLTVSQCVWHWPSDAVVYPAPIDHAPPAAAPRDSGESTERRPAQGGDEPAYLQPHQDGMPVQNIAWKAYAKTGEMLAKRFEEEAPAADNHIISYRDYPAGTPKDRLAGFLCRRVLDAERSGAPYILELPQRTVAPQNGQREICLTALALW
>NZ_CP022527.1|WP_094030830.1|172095_173007_+|AAA-family-ATPase
MTDNIQAALAQLNRLILGKEAVLKQLMACILADGHVLLEDVPGVGKTTLAHGLAAVLGLGYRRVQFTNDMMPSDLLGVSVYLPNDGKFEFHPGPVFHSFLLADEINRASPKLQSALLEAMEERQVSADGKTYRLPQPFIVVATQNPTEQLGTFPLPESQLDRFMMRLSMGYPAPEAEKTLYLQGDRRNALPQIQAVCNAETLRGWQQHAAHVRFAQAAADYVYRLVEATRRPGQFVTGLSPRAGLAVVNAAKAWAFMHGRGHVLPDDIKAVWVSVANHRLQPVQQGASSAQLLAGILSHVAVQ
>NZ_CP022527.1|WP_157697471.1|171938_172082_+|hypothetical-protein
MRPSETILSDGLNHSAERASERPSEKQGRLKRVSDGLHATILAFSTD
>NZ_CP022527.1|WP_009427641.1|169965_171846_+|phosphomethylpyrimidine-synthase-ThiC
MTAKNKNTGREAQDLADLSRDIGIRFPYPNSRRVYITGSRADIRVPLREIDQDDTVTAQGTEHNPPIPVYDTCGAYGDPAAAIDLKKGLPQIRTAWIDERGDSEILPRLSSRYGSERACDPKTAHLRFSQITRPRRARSGGNVTQLHYARRGIVTPEMEFAALRERMRLDELFRRPEYAKLLKQHPGHSFGANIPAHPDQITPEFVRREIAAGRAILPANINHPELEPMVIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWALRWGADTIMDLSTGAHIHETREWIIRNAPVPVGTVPVYQTLEKTGGIAEDLTWELFRDTLVEQAEQGVDYFTIHAGVLLRYVPLTADRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIADANDEAQFAELHTLGELTAQAWRHDVQVMIEGPGHVPLQRVRANMDEELRHCFEAPFYTLGPLVTDTAPGYDHITSGIGAANIAWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPERAESFHDATLPAEGAKTAHFCSMCGPKFCSMKITQEVRDYADRQKGLTQKAVEFVKNGAQIYR
>NZ_CP022527.1|WP_009427642.1|167410_169384_-|transglutaminase-domain-containing-protein
MLISNPVFLQEAPPRKVVAAVLLALLWSSLPLLAELPAGVTAVFGGLLLLRFALLRMGVAKLPLAAVVLLAAGAGLLVWQQLGTVIGRDGGISFLLLMVMLKSFEGNAMRDWQVLLLAMLFLIGSAVLFGQTLLTGLWLLAALLAVGLCFAVLCGLDARSALKQGLLAFGLTLPLAAVLFVVMPRRSEPLWSIPQPQQEQAKTGLSDTMQPGSIGNLVQSDELVANVTFSDGLKPGAGQLYWRAIVMADFDGQTWRAMPDFEEMSAPGVSDGLKLSYQMILRDQKGVVPALDYPVVREGSGMSVRLGDVVRVRSREGLRRVVLQSRAGGMLPQKLKEFEKKLYMRLPQSGNFRTRRLAQTLAQQSRSVGEFSQKVLDYYRNGRFAYTLQPPLYRGADSIDSFMFEGRQGFCEHYAQSYVVMMRAAGVPARVVTGYLGADYQESGNFWQIRSKNAHAWAEIWLEGEQAWLRVDPTAAVSEQRITAGLSEALPESDRAMVAGNHNGKMWGGWLESGQFYWQQWVVNYDESSQNNLFAGLGLGRFRFGTALLAGIVGIFAALLPVVWWWRRGRLKEREPLAEGFALLKSIFIGDEDETAAAVTASELIEMLRQNGVEDRELQDLLRQYEDWQFAAEIMPDKRTQRAWFGRAVRIARRYKQ
>NZ_CP022527.1|WP_009426524.1|166612_167101_+|inhibitor-of-vertebrate-lysozyme
MLRTVKILTALTLALAVAAPAAAKPAQTGQKSEQVSQKDADTYLFDLLKKPAYRKVWRSQIVPHTPKSDRYWIKDADGPTAPEGAVTVDGKRYIATTMCQPHNCISNSIYILLNKQRAVVLHRERHTVEGTYEFRYTDRYYGKPTEAEKAALQKLVDDEEEK
>NZ_CP022527.1|WP_009426523.1|165762_166470_+|DUF502-domain-containing-protein
MAEQTPEKEKNTIGKALKKYMLTGVLVWMPIAVTVWVIGYIINATDQLTALIPAQWQPERYLGFRVPGTGFIVALAVLFLTGVFAANMLGRKILEGWDSLLGRIPVVKSIYSSVKKVSESLLSDNSRSFKTPVLVPFPQRDIWTIGFVSGSLPDNIAAALPDAAPRIPVYVPTTPNPTGGYYILVKQSDIRELDMSVDEALKYVISLGMVLPDEAAAKAQSDAQRPSENTPESNV
>NZ_CP022527.1|WP_009426521.1|164412_165549_+|phospholipase-A
MKTNRYLPAALAVALPFAAYAAEDAALQCTLLQDNALRLACYDKIFAAQLPPVKAIEAPAAEVKPQPDVVRSIQDSVERKEPALVFEKEGQFEPSAELAEAAEAYTPLSRMYDLDANSSGGLLTVREHNPMYLMPAWYNSSPNRKPSSPTLGVTTAERFTDQKRTETKMQVSFKSKIAEDLFKSRADLWFGYTQKSDWQIYNQGNRSAPFRNTDYEPEIFITQPVKSKLPFGGRLRMLGLGFAHQSNGQSRPESRSWNRVYAMAGMEWGRLTVIPRVWTRVFEKNNDDNDNPDLAKYMGYGDLKLQYRLADKQNLSATLRYNPRSGRGAAEAAYTFPIKGKLQGIVRGFHGYGESLIDYNHKQNGIGIGLMFNGWDGF
>NZ_CP022527.1|WP_009427630.1|177304_177598_-|CRISPR-associated-endonuclease-Cas2
MLMLITYDISLQDPAGAARLNRIAKHCLDYGTRVQYSVFECDIAPDQWVKLKAKLLDTYNPETDSLRFYHLGSRWRRKVEHHGAKPALDVFQDTLVV
>NZ_CP022527.1|WP_009427629.1|177640_178654_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLQNTLYITGQGSYLHKERETLVVERERKKVAQLPVHAIGHIFCFGNVLVSPFLMGFCGENGVNLAFFTENGRYLGRLQGRQSGNILLRREQYRQSERNPVLVARNIVAAKIQASKRVLQRRLRNHGGSEDIQDAVAALNSSLRQLKRADSLDWVRGIEGDAAARYFAVFGSLIREGSGFAFNGRNRRPPRDAVNALLSLLYSVIGKEISGALQGVGLDPQAGFLHADRPGRDSLAQDILEEFRAWWADRLALSLINRGQLKTDDFVCESSGAVSLKDDARKRLFHSLQSKKQEKIVHPFLQEEVEIGLLPHIQAMLLARHLRGDLAEYPPFLMR
>NZ_CP022527.1|WP_009427628.1|178998_179673_-|CRISPR-associated-protein-Cas4
MQPATATADERTIPLSALQHYAFCPRQCALIHNEQAWAENFLTAQGRVLHERVDSGEPETRKGVRFERSVHVAAERLGIHGVLDMVERDLRSGSLKPVEYKRGRPKPDVCDEIQLCAQALCLEEMSGQTVAEGALWYGQTRHRVPVVFSDGLREQTLQTVAAVRELLAGGKTPPPEYGKRCKACSLAEICQPKLLSRDRSRRYAAALFDTADDEAADDADSETA
>NZ_CP022527.1|WP_009427627.1|179674_180544_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSLSKKIDFALIIKVQNANPNGDPLNGNRPRADFAGFGEMTDVCLKRKIRDRLQDAGESIFVQANERKDDGMVSLKNRYDHFVKQLKTENSTEETGKKNQKGSDLKKDIIAKEACKHWVDVRSFGQVFAFSGKDEDGVSIAVRGPVTLHSAFSIEPINITSTQITKSVNGDGDSDVKKSPDTMGMKHRVDSGIYVAYGAMSPQLAERTGFSDADAEKIKAVLPKLFEGDASSARPEGSMQVLKLIWWEHGCKSGQYSSAKVHGSLKVNADGSYVLNNLNGLQAQEIDGF
>NZ_CP022527.1|WP_009427626.1|180572_182624_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWMSKLYQTYEYAQKQNLDDEDLALPFHMPKAAHLKVVLNDKGELVCAERFDGKKQVPIQVTEKSSKRSGSTIAPYALHDNLQYIAKTAEQYLTIEYLSKVAEKKAPQKGGEKWKAFLSDNDDGRRKFADSEKEKFRNSFECYEKQLSDWADFSGLKEIQAVLQYIRKGSLIKDLLSHQVFTIEEDILLSKKDDPFGFTIVWAVEIPGDPHAELWSKNSVQADWIRYQESMSEQDSTQKDLCYITGEQEFPVAAYPKIQGNAKLISANDTGGLTFLGRFLTDKQAVILGRDVSQKAFNVLKWLIKRQGFKFGDQVTVAWAISGKRIPSPLQDTFVELDLDNLGSSIGKTEAKKQPENQEGGIDWSDNIGKAAAEIIKRKMRGYRADLEKHEQISLLMLDSATPGRMALTYYQEFLPDDYFANLDAWVDDTAWYQRHSINKKQTVWPILPPSPYAVYETVYGKRGSDTLKKQLYARLLPVIAGGSSVPLPYDLVQKSFQAACNPSGCEHWEWQRNIGVACALYKGWRARHHDSSQKRIYSMDLDLENRSRDYLFGRLLAVAEKLESTALRIADEERATTAERYMQRFAVHPLSTWLQIETNLVKSYKDRLRNNRYMGFLRNREKEIDEIMSALNELRDQTGCSLDTKLDGEFLLGYHSQKMAYRNKVNAQVQSDMQDDQAESN
>NZ_CP022527.1|WP_009427625.1|182620_183355_-|type-I-C-CRISPR-associated-protein-Cas5
MDNKISFRVWGRQALFTDPVTKIGGEKFSYQVPTYEAIKGILKSIYWKPTLIWHIDRIRVVKPIRTQSKSTKPRQWESLKGNHHTLAIYTFLQDVEYQVEAHFTWNENWEELAPDRIAGKHIAIARRMLERGGRQDIFLGTRDCQGYVEPCEFRSGEGFYDGIDNLDFGLMFHSFGYPEETGKPELVGRFWQAKMEYGVIEFPSVNDTTGRLKSRFIRKMQPEKPFKRGENLKAVENEAQELGL
>NZ_CP022527.1|WP_094030832.1|183372_185856_-|CRISPR-associated-helicase/endonuclease-Cas3
MSDNQFIAHVRKADGEQQLLETHLAETAEIAGLLAAKLGLGMAGKLLGLMHDFGKYSEKFQSYIRHATGLLDPDADEEENTPTDSKVDHSTAGAQWVYGRLKVFWAQYGIGELFGQMLGLCIASHHGAGLIDCLDPDNGEAVWRKRFNKDDALTHLAQCEQVADKSVLQQAQSLAGEALLKEMLTALDAIIRPMSESFNKERKHGEIRTPHKIEEFYLGCFTRFLFSCLIDADRINSADFEREAQKDVRRFAEMPDWQAAIDKLEAHLAQFPVRYPIDKIRRDISDTCLRRSGDLQGIYTLTVPTGGGKTLASLRYALHHAQKHRLDRIIYIIPYTSIIDQNARAVRDILGADWVLEHHSNLEPEQQSWQDKLLSENWDKPIVFTTMVQFLDAWFGGGTRGVRHVHAMTRSVLVFDEIQTLPVKCVRLFCNVLNWLAQYGCSSAVLCTATQPLLGQVPNPELGSLKLAKDAEIMGGGQDLDILFAGLSRVEIIPKLKAGGWSVDEAGAFLLERFQTASSCLFVVNTKRWAQELYQYCRRQNVPSDALFHLSTNQCAAHRRAIFDVIKQRLQDGKPVLCISTQLIEAGVDISMACVIRALGGLDSIAQAAGRCNRNGENTDKGQVYVLNLQEPDFSKVLPDITAGQANADRVFREFDGQDILQPDAMNRYFEYYFHQRGSEMSYTLANSVSGCLLDWLSDNSRNPYMPKNNKRGKAIPLLMQSFKSAGRAFAAIDAPTRAVIVPYGKGQELIAELCGAWDAKEMRRTLAQAQRYSVNVFPNVWERLQKAQAVRETLAGSGIYYLDERHYHEAYGLCVDEAGEMTFYDL
>NZ_CP022527.1|WP_009427623.1|186097_187495_+|ATP-dependent-RNA-helicase-HrpA
MLQPDFTQVLSKDRHFLQSAFKNPKKYGGQAKVEEKYQKSHDIFLKRQAALPKPEFDNTLPVHERLDDIKTAIQNNQVTIICGETGSGKTTQLPKICLELGRGAAGLIGHTQPRRLAARSVAERIAEELGQPIGQAVGYKVRFNDNTSRDASIKLMTDGILLAETQTDRYLAAYDTLIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDAERFSQHFNGAPVLEVSGRTYPVEIRYRPINERDEDEAEIDIPEAIVDAADELARLGDGDILVFLPGEREIREAAEALRKSPLRRNDDILPLFARLSAQEQHKIFHPTGSQRRIILATNVAETSLTVPRIKYVIDTGLARVKRYSARAKVEQLHVEKISQAAARQRSGRCGRVSAGVCIRLYAEDDFNQRSPFTDPEIIRSNLAAVILRMAALKLGDVAAFPFLEAPDQRYINDGFQVLLELGAVEEAV
>NZ_CP022527.1|WP_009427622.1|187570_188395_+|CPBP-family-intramembrane-metalloprotease
MNILSKYNRPVFFYFWSMLIPAVLWFGMAYLSHLPAQTDAAQVGQIVLGIAGLVSPMLVALHLFRQDADLWNDLKRRLSLHRHFSPLAVGLVLLLTYGSIMAAQAVSTLFGYSWAQFHISGQPSFQSAFVSAWFVLTFAPLVEELAWHSYGTDALLRKFSLFSASMIFGVYWVVWHLPLAFVKGYYHSNVVAEGALASVNFAASAFLFVLIMNWLYCKFGRNIWISVLFHLAANTANEIFDTHPDTKIIQTLIFLLFVMVLIAKDHKLFFAKYK
>NZ_CP022527.1|WP_094030833.1|188781_189543_+|SDR-family-oxidoreductase
MQNDFLNLSGKVAAVIGASSGIGRATALLLAKQGAAVVLCARRADELAQTAALIHEAGGRAEMVVGDARQSATHAAVVRTAEQAFGGLDIAVNNVGALGAYKPLAELSPDEWRDTLDSNLTTAFLGARSQIPAMLARGGGALVFTSSFVGSSVALPNLSAYGTAKAALSALAKGITADYAAQGIRANVVLSGGADTDMAGNAEQKVWAAGLHAVKRIAQPEEIASVIAFLASPAAGFVTGASLFADGGNASVK

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Crispr_ID: NZ_CP022527_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022527_2

915467-915614

Orphan

Consensus_repeat	Method
TTTCAGACGGCCTCTTC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP022527_2

>merge|NZ_CP022527|2|915467-915614|PILER-CR
TTTCAGACGGCCTCTTCACAACCAAGCCGCAGGTAATTCCCCAAATAAAAAAGGCCGTCTGAAACACCGTTTTCGGGTTTCAGACGGCCTTTTCTTTGCGCCGCTGTTTTTTAACTTTGTTGAAGCGGCGCTTTCAGACGGCCTCTTC

>NZ_CP022527|2|2|915467-915614|PILER-CR
TTTCAGACGGCCTCTTC	ACAACCAAGCCGCAGGTAATTCCCCAAATAAAAAAGGCCGTCTGAAACACCGTTTTCGGG
TTTCAGACGGCCTTTTC	TTTGCGCCGCTGTTTTTTAACTTTGTTGAAGCGGCGC
TTTCAGACGGCCTCTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022527.1\|WP_036496552.1\|926584_927397_-\|shikimate-dehydrogenase	unknown	unknown	gnl\|CDD\|234703
NZ_CP022527.1\|WP_009427014.1\|924258_925527_-\|divalent-metal-cation-transporter	unknown	unknown	gnl\|CDD\|224826
NZ_CP022527.1\|WP_036496555.1\|919357_921694_-\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|224369
NZ_CP022527.1\|WP_009427019.1\|918389_919361_-\|PPIC-type-PPIASE-domain-protein	unknown	unknown	gnl\|CDD\|234605
NZ_CP022527.1\|WP_009425561.1\|902451_902871_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224892
NZ_CP022527.1\|WP_157058148.1\|927465_929025_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341039
NZ_CP022527.1\|WP_094030977.1\|929149_930010_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_009425556.1\|904689_906993_+\|DNA-topoisomerase-IV-subunit-A	unknown	unknown	gnl\|CDD\|235503
NZ_CP022527.1\|WP_009427024.1\|912341_913394_-\|outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|379226
NZ_CP022527.1\|WP_036496556.1\|913845_915429_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP022527.1\|WP_009425557.1\|903869_904562_+\|LrgB-family-protein	unknown	unknown	gnl\|CDD\|377236
NZ_CP022527.1\|WP_036496554.1\|921763_922768_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|225719
NZ_CP022527.1\|WP_009427015.1\|923210_924095_-\|lysophospholipid-acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|236348
NZ_CP022527.1\|WP_009427026.1\|910604_912044_+\|DUF560-domain-containing-protein	unknown	unknown	gnl\|CDD\|368004
NZ_CP022527.1\|WP_009425558.1\|903528_903870_+\|CidA/LrgA-family-protein	unknown	unknown	gnl\|CDD\|224298
NZ_CP022527.1\|WP_094030976.1\|908709_910431_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP022527.1\|WP_009427016.1\|922842_923109_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_009427012.1\|925898_926582_-\|monofunctional-biosynthetic-peptidoglycan-transglycosylase	unknown	unknown	gnl\|CDD\|234603
NZ_CP022527.1\|WP_036495688.1\|907124_908723_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP022527.1\|WP_009425559.1\|902990_903278_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022527.1\|WP_036496552.1\|926584_927397_-\|shikimate-dehydrogenase	gnl\|CDD\|234703	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed.	2.80919e-104
NZ_CP022527.1\|WP_009427014.1\|924258_925527_-\|divalent-metal-cation-transporter	gnl\|CDD\|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	6.28582e-61
NZ_CP022527.1\|WP_036496555.1\|919357_921694_-\|LPS-assembly-protein-LptD	gnl\|CDD\|224369	COG1452, Imp, Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane].	2.04365e-152
NZ_CP022527.1\|WP_009427019.1\|918389_919361_-\|PPIC-type-PPIASE-domain-protein	gnl\|CDD\|234605	PRK00059, prsA, peptidylprolyl isomerase; Provisional.	4.44018e-33
NZ_CP022527.1\|WP_009425561.1\|902451_902871_-\|hypothetical-protein	gnl\|CDD\|224892	COG1981, COG1981, Predicted membrane protein [Function unknown].	1.06701e-45
NZ_CP022527.1\|WP_157058148.1\|927465_929025_-\|MFS-transporter	gnl\|CDD\|341039	cd17486, MFS_AmpG_like, AmpG and similar transporters of the Major Facilitator Superfamily. AmpG acts as an inner membrane permease in the beta-lactamase induction system and in peptidoglycan recycling. It transports meuropeptide from the periplasm into the cytosol in gram-negative bacteria, which is essential for the induction of the ampC encoding beta-lactamase. The AmpG family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.65658e-49
NZ_CP022527.1\|WP_009425556.1\|904689_906993_+\|DNA-topoisomerase-IV-subunit-A	gnl\|CDD\|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0
NZ_CP022527.1\|WP_009427024.1\|912341_913394_-\|outer-membrane-beta-barrel-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	4.5501e-13
NZ_CP022527.1\|WP_036496556.1\|913845_915429_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP022527.1\|WP_009425557.1\|903869_904562_+\|LrgB-family-protein	gnl\|CDD\|377236	pfam04172, LrgB, LrgB-like family. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance.	6.53126e-73
NZ_CP022527.1\|WP_036496554.1\|921763_922768_+\|phosphotransferase	gnl\|CDD\|225719	COG3178, COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only].	4.56076e-131
NZ_CP022527.1\|WP_009427015.1\|923210_924095_-\|lysophospholipid-acyltransferase-family-protein	gnl\|CDD\|236348	PRK08905, PRK08905, lysophospholipid acyltransferase family protein.	2.34779e-136
NZ_CP022527.1\|WP_009427026.1\|910604_912044_+\|DUF560-domain-containing-protein	gnl\|CDD\|368004	pfam04575, DUF560, Protein of unknown function (DUF560). Family of hypothetical bacterial proteins.	1.67722e-92
NZ_CP022527.1\|WP_009425558.1\|903528_903870_+\|CidA/LrgA-family-protein	gnl\|CDD\|224298	COG1380, COG1380, Putative effector of murein hydrolase LrgA [General function prediction only].	2.26286e-31
NZ_CP022527.1\|WP_094030976.1\|908709_910431_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.47563e-129
NZ_CP022527.1\|WP_009427012.1\|925898_926582_-\|monofunctional-biosynthetic-peptidoglycan-transglycosylase	gnl\|CDD\|234603	PRK00056, mtgA, monofunctional biosynthetic peptidoglycan transglycosylase; Provisional.	5.2642e-102
NZ_CP022527.1\|WP_036495688.1\|907124_908723_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.41797e-33

>NZ_CP022527.1|WP_036496556.1|913845_915429_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MSTVKIQRALISLSDKNGAVEFARALHEAGVEILSTGGTAALLADAGIPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLAEHVAKMQEHGIGNIDLVAVNLYPFAATIAKPGCTLEDAIENIDIGGPTMVRSAAKNWKHVAIVTDNADFAAVIAELKSSDGLSDKTRFNLSRKAFSHTAQYDGMISNYLTSLSDDKLAGEPEIGEFPQQFNQSWLKVQEMRYGENPHQRAAFYRDVYPFSGCLSNYTQLQGKELSYNNIADADAAWEAVKSFDAPACVIVKHANPCGVAVADNTLAAYRLAYATDTTSAFGGIIAFNREVDGDTVKQITDNQFMEVLMAPKFTAEALEIAAAKKNVRVLEVPIDSGANRFELKRVGGGLLVQTPDIHRIRREDLKVVSKRQPTEQEWKDLLFVWNVAKYVKSNAVVFGKGGQTYGIGAGQMSRVDSTRIAARKAQDAGLDLNGACAASDAFFPFRDGVDVIAEQGIKAVIHPAGSVRDEEVFAAADEHGMAMVITGVRHFRH
>NZ_CP022527.1|WP_009427024.1|912341_913394_-|outer-membrane-beta-barrel-protein
MKHLKLLPALTVSALALMSASAQAGMVSDAHGNVGYDTAAECDAAVQNGTARFYQSATHQKPLLHKGERSVATATLRDLGPQYALGACDIGVGRKFNRDGVARALQGKYVPYSPDMAVNVYSDAAGQPVRVSMQQCDNRFSDNVPRPVPMPERQPEPVAAPEPAPQPVPEPQAKSSVRPYVFGTLGALRDGYKYESAAETEQAHDTRFAGQVGAGVQFNELLGAEAFYQGGQKHRYRYDDGSNDEVRTQNHTYGARATVGGNVSDKFRLFGKAGVAGVKHKITDADGEKVSSKTKARPTVGVGMTYNFTDNLALRADYDYYFRKKESQTDGDKFTWKANHYLGAGLQYTF
>NZ_CP022527.1|WP_009427026.1|910604_912044_+|DUF560-domain-containing-protein
MPKRLPFLLLLATLSAARADELPNPAARSALSQPDTRFDLTGSDELPAPASAPESSVSQNGGTLTCSNPEELLQHPGLLHRALSSSVIAANTAAIKLLLPVYRRLPEGQDPVLLETAEGMAAQSDGRYREAVRRLQNARRQMPDAFLVRLRLAQALKDDRRNVSAQAHYTNLLAPPDLDPQTRAALQSQLDEIRSRSRWTPRLSANYTRDNNVNNAAKEHTLRYGNGEWTLPAPEKARGLSYSAGLARDFNLADNLLLRSETDLYGKFYWDNHRYNDLTVRTALGAAYQSGRSEAALLPYYERRWYGTEPYSRETGLRAEWQRSLSPRHRLAAAAESDYQHYDTRKFLEGRNSSLSATWIFQHSPRQYFTLGANFSRKRARTDDAYHRRGIRASAVRVWGKGLGTALSAGYGRRYDAADFLAIRRDDKEYSASLSLWHKRLSLWGVTPRLVTVWQKTTSNHPLYGYRKANAYLQISKSF
>NZ_CP022527.1|WP_094030976.1|908709_910431_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MKNSDLQHPVLVVDDEADIRDLMEMTLMKMGLRVDTAVGVEDAKDKLENSDYSLVLTDMRMPDGSGLEVVQHINRLSLDTPVAVITAFGNADQAVEALKEGAFDYLQKPITLSQLRSLVKSAVKVNEPEAAETKPAAPAPQPAPAAPYMPPPVPPRPQPVAATPARAPDAPKPVRKGISGGIDRPVTPPSALSSLRERFRSATPQTAAASDAQAPAHHENEVGGDADMPRLLGMSPQMVEVRHLIRRLAGSGVPVYISGESGSGKEQAARSIHELSPRADGPFIAVNCGAIPENLMESEFFGYKKGSFTGADQDRMGFFQHADGGTLFLDEVADLPLAMQVKLLRAIQEKAVRRIGDAKETPVDVRIVCATHKNLEALVESGAFRQDLYYRLNVVTLHMPPLREMREDLGGLIMRMLNKHGNGIPGGYRLSPKAQEALLSYSYPGNFRELENILERAVALTAGSVIQIDDLQITAGHGPRPADLAPAAAPAGETRAPRPEPAAESEELPPMNFDAMPPFVPGQSQIQEYLDLLERSIIEQALNITRYNRTQAAKLLGISFRSMRYRMERLNIE
>NZ_CP022527.1|WP_036495688.1|907124_908723_+|HAMP-domain-containing-histidine-kinase
MKNSFLSRTDDWEEQIDRIPWLINICRLTIVTAMTALHLMAMFSDNAGLRKMVTPATFYLWAAVYAGITLFSFVRPHWVQQKTDRLPNASAVIDILMIMVLVYLTGGIGTGIGILVLPFIATSCMLSYGRFPALYAGFTTLCIVCVMFLTDQLVLDTQQWDGRNIGTGIVLIAASFAVAYLTSYSAKFLKAANASALKHKRNYNRVRGLNLLVLNRVQEAVIVIDPELKVWLFNRQAKTYFPGLAPEQKEPIFEDLAGRWLYNPDRPFETDIHLHQHSMHVRAVPLVQEDGQLLMLFVRSLREIAAEAMATKLASLGQLTANLAHEIRNPMSAIRHANDLLQEGVEDPMSRKLHGIIDGNIRRIDKMLEEVSMLNKKDNLGREHINLMKFWLAFKQEFTLSNPDAVHCIKMEMQGKQLAVTADPMHLQQIMWNLCNNAWRHSKKDESAIRVLIRPSGKLNISIVVSDNGAGVPPDIRNQLFEPFFTTEKTGTGLGLYVARELAHANLGQLHYHPEMNGFELILPKDNNHEEQ
>NZ_CP022527.1|WP_009425556.1|904689_906993_+|DNA-topoisomerase-IV-subunit-A
MIHDTPSPVSDHDTLLLGQYAERAYLEYAMSVVKGRALPEVSDGQKPVQRRILYAMRDMGLTSGAKPVKSARVVGEILGKYHPHGDSSAYEAMVRMAQDFTLRYPLIDGIGNFGSRDGDGAAAMRYTEARLTPIAELLLSEIHQGTVDFVPNYDGAFEEPVTLPARLPMVLLNGASGIAVGMATEIPPHNLNEVTQAAVALLKKPHLDTADLMEYIPAPDFAGGGQIITPAADLRQIYETGKGSVRVRARYEIERLARGQWRVIVTELPPNANSAKILAEIEEQTNPKPKAGKKQLNQDQLNTKKLMLDLIDRVRDESDGEHPVRLVFEPKSSRIDTDSFINTLMAQTSLEGNVSMNLVMMGLDNRPAQKNLKTILQGWLDFRVVTVTRRLKFRLSQVQKRLHILEGRLKVFLHIDEVIKVIRESDDPKTDLIAAFGLSEIQAEDILEIRLRQLARLEGFKLEKELVELREEEGRLNLLLGDENEKKKLIIKEMQADMKQYGDARRTLVEEAGRAVLTQTTADEPVTLILSEKGWIRSRAGHNLDLSQTAFKEGDALKQTLEGRTVWPVVILDTQGRTYTLDAAEIPGGRGDGVPVSSLIELQNGAKPAAMLTGLPEQHYLLAGSGGYGFIAKLADMVSRNKNGKVLMTLETGETVLPPAALYASSLINPDCKVVTADSGNRLLAFPLGELKVMPKGRGLQLTPLSDGLTLEHTAVVSTPEFVVETVGKRGAVHQEKLRIQDIAGKRGRKGKILEVSGRLKAIKAKD
>NZ_CP022527.1|WP_009425557.1|903869_904562_+|LrgB-family-protein
MDMLRHPAVLLWLTVTAYWLVNIVRARTGNVLFNPVMCTTALVIIYLKLCGIAYPDYHQAAQFIDFWLKPVVVGLAVPLYLNWDRIRRQWLPIILSQTAGSVTGIVSAVYLAKLAGAGRETVLSLAAKSVTSPIAIEITRSIGGLPAITAASVIAAGMIGQTAGYRILQLGTVKKPMSQGMSVGAASHAMGMAASLERSKKYAAYAGLGLIVNGVLTAFLVPLLLPLMGY
>NZ_CP022527.1|WP_009425558.1|903528_903870_+|CidA/LrgA-family-protein
MHLIRALSIIFGFLAAGEAVIHFTGLQLPGSIIGMALLFAALQAGWVKTAWLQGAVDTMMANLSLFLVPPCVAVMEYLDLVARDFWPIAVSTVFSTLAVMFVTGKTHELLRKR
>NZ_CP022527.1|WP_009425559.1|902990_903278_+|hypothetical-protein
MLNQFEIHGGVVKNLNAFLAEKAVDLKTAMDDEALNKEVAAIIHAGLPGMVRRIYSLQKMETFFWEKKDLMVDYVAARLEASAKKAEAREKKEKK
>NZ_CP022527.1|WP_009425561.1|902451_902871_-|hypothetical-protein
MYLWFKFLHLFFIISWFAGLFYLPRIYVNLAQADAGSAEYRRLLDMARRLLRFMTPLGAGALVFGLLVPFAAGWWGQGWVYGKLALGLFLAAYHVCCFFLLRGFAAHRNRRSHKWYRVFNEIPVLAMIAALYLVVFKPF
>NZ_CP022527.1|WP_009427019.1|918389_919361_-|PPIC-type-PPIASE-domain-protein
MKSHTKILAAALIGAAFQTAFAADIKTVDGIAAVAGDSVVTMSQFERALAEAKRRIPAAQRPSENELRRHVLAQLVNRALVVQAGKRRGLSASEAEVDEAIALAAAQKHVSIDKFYADALKEGAPKSAVRRETAEQIIAEKVQQQAVLQSARVSDAEVDAAIARAQQQGIAIPAGEPVRQYRAQHILIKAEKENASAAAEAVIRKIQNQAAAGRDFGELARQYSQDPGSAQQNGDLGWFGDGVMVPEFESTVKKLKKGQISRPVKTQFGWHLIKLTDTREAGTPEERRRNAVRQYIMEQKAAQAGSQLLQQLHEGAFVDVRLK
>NZ_CP022527.1|WP_036496555.1|919357_921694_-|LPS-assembly-protein-LptD
MARLFSVKPLAIAVGMAAAAGSAAAATSALGSTCPQCKDGKPVQTASQPENAVRRSGEETLPADYTRITADDVRGQTGVGVEARGGVIIERNAQVLNAERVVYDQPEDTVKAGEGFILDDAGSTVRGDKLQYNLTEGSGTAQNVEIEAERDGRRLQAVGKEAEIERKNRYKLTDVQFNTCQKGDASWYIAADSIDADYGKGVGVAKHAKLVFHGVPVLYTPWADFPLNGNRKSGLLVPTLKIGSNGTEIDQPYYFNLAPNYDATLTPGIISARGVQLGGEFRYLQPKYNGEIAGKWMPDDRRSRHNNRYTAQWRHTQDFGKGLSGKVDFNQVSDDDYYRDFYNRTDIARNVNLNREARLDYKTDVLGEWLEANLKVQKYQTLANADGYKNEPYAILPRLSGSWQKNFAGNLFSLSGQYTRFAHDSKQAGQRFVLYPSLSRNIHNDWGYIRPKVGLHYTHYILDGFNDKSGRTAGRSIPIANIDAGMAFERETRFFGRDHIQTLEPRLFYNYIPTKSQNDLPNFDSSENSFSYDQLFRENLYSGNDRINAANSLSLALQTRYLDRASGAERIRAGIGQKFYFKNDSVLADGNIGSGKRNRSDWIAFADGEISRSVSGYATAHFNENQSRFENLAAGIRYTPEDGKTLSARYRYGRDKAIWLQDDGSYYRDKISQIDLGAQWPITSNLYALARYNYALNVRKPLDILAGLEYKNDCGCWSVSAAAQRYVSGWDTERNKPSYKNAFFFTLQLKNLSNIGNKADETLRPAIPGYKKTNEVVK
>NZ_CP022527.1|WP_036496554.1|921763_922768_+|phosphotransferase
MQRQSELKNWLAAVYPNQAFELSFAAADADFRRYFRAAFSDGQTIICMDAPPDKMSVAPYLKVQKLFDMVNVPQVLHVDEAHGFMALSDLGSTTYLAAMQHDTREIVHKTLLLEAIDELVTLQTASKPDVLPEYDRETMLREINLFPEWFAAKELGKPLNFKQRQLWQQAVDTLLPPLLAQPKVYVHRDYIVRNLMLTRGRPGVLDFQDALYGPISYDLVSLLRDAFIEWEEEFVLDLVIRYWEKARAAGLPVPQDFDEFYLWFEWMGVQRHLKVAGIFARLYYRDGKDKYRPEIPRFLNYLRRTSRRYADLAPLYALLVDLVGDDDLQTGYTF
>NZ_CP022527.1|WP_009427016.1|922842_923109_-|hypothetical-protein
MSNPFLLKLLLMLAAGYLIGLTARALLPGDNGMGFLRTWLLGTVGVLTAYGVCYFFGWLEFYHRNIYTSVAAILLGTMVWIPLFRRRA
>NZ_CP022527.1|WP_009427015.1|923210_924095_-|lysophospholipid-acyltransferase-family-protein
MQSLVFFLFRLFAALPLKVLHRIAHFWGGLAFYILREDRDRIRANLQTADLPSGDAAVKTILRETAKGGLELPVAFFRRPEEIEALFKAVHGWEHVGQALAEGRGLLFITPHLGSYDLAGRYISQRLPFPLTAMYKPPKIKAFDAVMQAGRVRGKGKTAPTNIQGVKQIIKTLRAGEAAIVLPDHVPAPEEGGDGVWAPFFGRPAYTMTLAGKLAQVKNVAAFFFCGERLPNGQGFVLHIEPLRGTLNGDKAHDARIINENTEYWIRRFPQQYLFAYNRYKQPAGAPEPPVAAE
>NZ_CP022527.1|WP_009427014.1|924258_925527_-|divalent-metal-cation-transporter
MSENTPNTPAVSTWQTRLRALGPGILMASAAIGGSHLIASTQAGALYGWQLALIIVLTNLFKYPFFRFSAHYTLDSGKSLIEGYAEKSRAYLWVFLVMCFLSSTISTGAVALLTAAIVKMAVPSLPFSVGVLSVVVVGSCVLILLTGRYKALDNLSKIIVVSLSITTVAAAAIAASKGMQMKPDFVEPSPWTLAGLGFIIALMGWMPAPIEISAINSLWVTAKQKSDPASYRDGMFDFNVGYITSAVLAVVFLALGAFVQYGNGEAVQMAGGKYVGQLINMYTGTIGAWSRPLVGFIAFACMFGTTITVIDGYARAVAESVRLVRGRETFRTRELLAWIGWVSFSGLALILWFDSALAELLKFAMISAFLAAPVFAWLNYRLVRGDKKHRLTPAMNALAVVGLVYLVGFAVLFVLNESGILA
>NZ_CP022527.1|WP_009427012.1|925898_926582_-|monofunctional-biosynthetic-peptidoglycan-transglycosylase
MLKWILALPFALFILFNAYVYGSILTFRAVAPHHSAFMTARMAEFRREGRDIPLDYRWRAYPDISANLKKALIASEDAAFAEHGGFDWNGIRNAIKRNEKSGRIKGGGSTISQQLAKNLFLSEWQSYIRKGEEAAITAMLEATTDKDRIFELYLNIIEWDYGVYGAEAAAQKFYGKPAANLSKQQAAALAARVPAPLYYADHPQSKRLRSKTNIILRRMGSAALPEE
>NZ_CP022527.1|WP_036496552.1|926584_927397_-|shikimate-dehydrogenase
MTQTPLYAVFGNPVAHSKSPPIHQMFAAQEGVQIVYERRLSQPDTFACDIAAFFAAGGAGANVTLPFKTQALALAHEQSERAAAAGAANTLILLSDGLIRAENTDGLGLVCDITRNLGISLCGKRILVLGAGGAVRGVLQPLLGENPAELAIANRTHAKAEALARQFGIAAVETGRLKSGFDIIVNGTSGSLSGQTPDIPAAVFQNCALAYDMAYADTATAFQTAAAKNGAAQTADGLGMLVCQAAESYRLWRGFAPDTAPVIAALRKAV
>NZ_CP022527.1|WP_157058148.1|927465_929025_-|MFS-transporter
MPPLPAPVFPMNKPSPGRRSAFAAYTDSRAIILFFLGISAGMPILLIFSSLSLWLREAGVARETVTMFSWAALAYSFKFVWAPLVNSLPLPFLHKMLGRRRSWLLLAQAGVVSAAAAMAMVDPADPQALRLMAAAAVLLGFSSATQDIVIDAYRIEAAAGDAAMQSVMSATYSAGYRIGMVVSGAGALFLAAKLGSAAEHYSYEAWRQTYLAMAAVMAAGVLTTLLMREPEAAAAVQTSCPPLDHLRLVLLFLGAVSAFVAAFVWVGGLLPKADGALSGLAWETLRLAAALASAAAAGALLVTAKVAPAALAVQTWVSPVTDFFRRYGRSALLLLALIGLYRISDIVAGVISNVFYQDLGFSKEEIAWAVKTFGVLMAIAGGFVGGALSQRYSLMKMMMLGAVLAAATNLLFVALAYQGRDLTLMYLAVGSDNLASGLAGAVFVAFLSVLTNIRFTAVQYAILSSLMTLLPKTLGGYSGTMVESIGYPGFFLFTALLGLPVLLLVYLVDKKIYRNNQAV
>NZ_CP022527.1|WP_094030977.1|929149_930010_+|hypothetical-protein
MRDTENYYGYGGYGSDYDNGVPYLLDAPSWRPIGDIAVWLKHTLLLVGGRLPQWILAILLMLVSIVVMAWGSFFAMAALDIQTATAQHKWWAYVLSFAVLLFVQMLPLLFAAGFVSIAAGVSEERSFVFGRLFSGFGERKWVLVRLYLFWFLAATACLMAVANLKNPGESRIFWALFGIVPLFFLCNWMSLPLIMLQGVPAAKAMWMSLTGSLKNIAQLGVFLLITLVLGYGAVTLLLFKTAKMTVEHNNLIFAAGLLLFYAVVFPLLPVISYVSYRNIWTTSPLK

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Crispr_ID: NZ_CP022527_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022527_3

967628-967712

Orphan

Consensus_repeat	Method
GGCCGATGCGGCCGCTGTTGGCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022527_3

>merge|NZ_CP022527|3|967628-967712|CRISPRCasFinder
GAGTCAGGCGGCCGCTGTTGGCCATTTCGCTGCTGACGCTCAGATCGGTGCGCCCGCCTGCTTCGATGGTGCCGCTGTTGTCCAA

>NZ_CP022527|3|2|967628-967712|CRISPRCasFinder
GAGTCAGGCGGCCGCTGTTGGCCA	TTTCGCTGCTGACGCTCAGATCGGTGCGCCCGCCTG
CTTCGATGGTGCCGCTGTTGTCCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022527.1\|WP_009426977.1\|953348_953624_-\|50S-ribosomal-protein-L27	unknown	unknown	gnl\|CDD\|235464
NZ_CP022527.1\|WP_094030981.1\|977110_977779_+\|DnaA-regulatory-inactivator-Hda	unknown	unknown	gnl\|CDD\|236347
NZ_CP022527.1\|WP_009426168.1\|978454_978778_+\|divalent-cation-tolerance-protein-CutA	unknown	unknown	gnl\|CDD\|376987
NZ_CP022527.1\|WP_009426176.1\|972038_972689_+\|DUF4375-domain-containing-protein	unknown	unknown	gnl\|CDD\|379547
NZ_CP022527.1\|WP_009426173.1\|973924_975871_+\|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl\|CDD\|235549
NZ_CP022527.1\|WP_094030980.1\|957198_957630_-\|transposase	unknown	unknown	gnl\|CDD\|290319
NZ_CP022527.1\|WP_009425201.1\|959537_960494_-\|immunity-49-family-protein	unknown	unknown	gnl\|CDD\|373949
NZ_CP022527.1\|WP_009426171.1\|976290_976938_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|182775
NZ_CP022527.1\|WP_009426180.1\|969352_971095_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP022527.1\|WP_009117569.1\|953652_953961_-\|50S-ribosomal-protein-L21	unknown	unknown	gnl\|CDD\|235510
NZ_CP022527.1\|WP_009426974.1\|955444_956377_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|225375
NZ_CP022527.1\|WP_009426177.1\|971530_971815_+\|ribosome-assembly-RNA-binding-protein-YhbY	unknown	unknown	gnl\|CDD\|224451
NZ_CP022527.1\|WP_009426172.1\|976018_976162_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_009426979.1\|952984_953188_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_157697513.1\|956422_957010_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_094030982.1\|977775_978453_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319796
NZ_CP022527.1\|WP_009426184.1\|957846_958095_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_009426175.1\|972826_973663_+\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NZ_CP022527.1\|WP_083479448.1\|958091_958391_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373059
NZ_CP022527.1\|WP_009426975.1\|954181_955156_+\|octaprenyl-pyrophosphate-synthetase	unknown	unknown	gnl\|CDD\|182813

Protein	Function_ID	Function_description	E-value
NZ_CP022527.1\|WP_009426977.1\|953348_953624_-\|50S-ribosomal-protein-L27	gnl\|CDD\|235464	PRK05435, rpmA, 50S ribosomal protein L27; Validated.	7.05957e-52
NZ_CP022527.1\|WP_094030981.1\|977110_977779_+\|DnaA-regulatory-inactivator-Hda	gnl\|CDD\|236347	PRK08903, PRK08903, DnaA regulatory inactivator Hda; Validated.	2.69146e-87
NZ_CP022527.1\|WP_009426168.1\|978454_978778_+\|divalent-cation-tolerance-protein-CutA	gnl\|CDD\|376987	pfam03091, CutA1, CutA1 divalent ion tolerance protein. Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs. This family also contains putative proteins from eukaryotes (human and Drosophila).	2.66248e-37
NZ_CP022527.1\|WP_094030982.1\|977775_978453_+\|HAD-family-hydrolase	gnl\|CDD\|319796	cd02612, HAD_PGPPase, phosphatidylglycerol-phosphate phosphatase, similar to Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C. This family includes Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C, PgpC (previously named yfhB) which catalyzes the dephosphorylation of phosphatidylglycerol-phosphate (PGP) to phosphatidylglycerol (PG). This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.85253e-63
NZ_CP022527.1\|WP_009426173.1\|973924_975871_+\|RNA-polymerase-sigma-factor-RpoD	gnl\|CDD\|235549	PRK05658, PRK05658, RNA polymerase sigma factor RpoD; Validated.	0
NZ_CP022527.1\|WP_094030980.1\|957198_957630_-\|transposase	gnl\|CDD\|290319	pfam13586, DDE_Tnp_1_2, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	7.54764e-12
NZ_CP022527.1\|WP_009425201.1\|959537_960494_-\|immunity-49-family-protein	gnl\|CDD\|373949	pfam15575, Imm49, Immunity protein 49. A predicted immunity protein with an all alpha-helical fold and a conserved proline residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Tox-REAse-1 or Tox-REase-6 families.	3.77345e-10
NZ_CP022527.1\|WP_009426171.1\|976290_976938_-\|DedA-family-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	1.37106e-111
NZ_CP022527.1\|WP_009426180.1\|969352_971095_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	1.23762e-175
NZ_CP022527.1\|WP_009117569.1\|953652_953961_-\|50S-ribosomal-protein-L21	gnl\|CDD\|235510	PRK05573, rplU, 50S ribosomal protein L21; Validated.	7.62515e-53
NZ_CP022527.1\|WP_009426974.1\|955444_956377_+\|alpha/beta-hydrolase	gnl\|CDD\|225375	COG2819, COG2819, Predicted hydrolase of the alpha/beta superfamily [General function prediction only].	4.7542e-49
NZ_CP022527.1\|WP_009426176.1\|972038_972689_+\|DUF4375-domain-containing-protein	gnl\|CDD\|379547	pfam14300, DUF4375, Domain of unknown function (DUF4375). This family of proteins is found in bacteria. Proteins in this family are typically between 156 and 204 amino acids in length. There is a single completely conserved residue G that may be functionally important.	9.248e-14
NZ_CP022527.1\|WP_009426177.1\|971530_971815_+\|ribosome-assembly-RNA-binding-protein-YhbY	gnl\|CDD\|224451	COG1534, COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis].	3.56806e-34
NZ_CP022527.1\|WP_009426175.1\|972826_973663_+\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.15176e-99
NZ_CP022527.1\|WP_083479448.1\|958091_958391_-\|hypothetical-protein	gnl\|CDD\|373059	pfam14424, Toxin-deaminase, The BURPS668_1122 family of deaminases. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Burkholderia BURPS668_1122. Members of this family are found as toxins in polymorphic toxin systems in a wide range of bacteria and in the eukaryote Perkinsus. Members of this family typically possess a DxE catalytic motif in Helix-2 of the core fold instead of the more common C[H]xE motif. The Perkinsus versions are predicted to be inactive.	7.43332e-13
NZ_CP022527.1\|WP_009426975.1\|954181_955156_+\|octaprenyl-pyrophosphate-synthetase	gnl\|CDD\|182813	PRK10888, PRK10888, octaprenyl diphosphate synthase; Provisional.	8.32688e-133

>NZ_CP022527.1|WP_009425201.1|959537_960494_-|immunity-49-family-protein
MSFMCSKKWYDHISSIVIEYAESFNQYLSGKGDPDIAYHLSYIDERKGSPFAAMSNLQRRVYAACAHALWAERDLPKFKRYAYQLGKLEILSSMGWSYPEPFFLCAETPNVANPLFVMLMSDSPKIRSFLLRNIDLISNDTEEFADRYDLNRQLKYNTLLMLEGTQLERLERRSLNVLENQQQSKWLQLRCEDFLFFLAFARQDPAAMRQALDPLFEKKRARQAAKETLSYFDFFLQPQIVMYAKIAAIHGFDLGIDHEIAPKEAIAYAPLPEGEYQDPFDFMRTYDLDFPYEYLQNWVDYYTGQTDTLGLPPLVNDE
>NZ_CP022527.1|WP_083479448.1|958091_958391_-|hypothetical-protein
MWRSSSLDRVTNEPKIFTATEVKGKNGNAWLRHTDSEYRMLNDLAYKLGGKPGHVYHQVYGHLTIVSEYPYCTSCTHVIQQFQTMFPNLRLTLINGVKK
>NZ_CP022527.1|WP_009426184.1|957846_958095_-|hypothetical-protein
MINKKLEFKVLVMDLDILEKAVEMYNLDPTSNVKFQIINEIEDSLNSATIQSDKYNIEEVFRLGYRLADLENYLQNKGEFDW
>NZ_CP022527.1|WP_094030980.1|957198_957630_-|transposase
MVLSVGKQLAVINAVVGKSAYIQHIIAAQTIRIELLPGQRNDICGVLSLIKDKSFGALFADKAFDADWLIKELTQKGIEPVIPPRKGRNTERCYDRGKYKWRHLIENFFCRIKEFKKIAMRCEKTDESFAANIYLAATVLRLA
>NZ_CP022527.1|WP_157697513.1|956422_957010_+|hypothetical-protein
MFFRITNHPHSKRFTALHIKRSSESFNFVEASLSDGLYYRFDDGSGCGAAVARRMLEYEELYKKRLEKHKKIIQKQVEINHGQIIRHHEIQQFFHNLHLAFIHMLSSQASERALSAFNDTVVANTSIEKLKKVEWMMSSEMHKEYEETLPLLKNEMNASKHAFWHKKSPEEQEKFAKIFKQNKVVINAMAKNEDG
>NZ_CP022527.1|WP_009426974.1|955444_956377_+|alpha/beta-hydrolase
MKTLITALALLPALAAAAPSSSPNNEITRPADLSALTAPHSGYTFQTLAFQDQNGRAYRVFLGIPDSPPPAAGYPVLYALDGNALPEYLAAPALQDLSANPPVLVLIGYPTDLRFDTTRRAYDYTPPDLSGNSLPDQLMDGRRNGGAPALLELIDGKIRPAVERAAHTDPARQALWGHSYGGLFVLYTLFQRPQTFTRYIAADPALWWQNGLMLRYAERAAAKADAYSGRSLLLEKSGKAHHKQPADAKQADMLAKRAAVIASVPADAGEKLVAKLRGQGLAAEYRHYPDLTHGGLLGISFKQALPAAAR
>NZ_CP022527.1|WP_009426975.1|954181_955156_+|octaprenyl-pyrophosphate-synthetase
MLEHLPYFQQNLAADLGRVNQVVERAVQSEVALISQIGNYIIGAGGKRLRPIITILAGKSLGYDDDKLYSLAAMVEFIHTSTLLHDDVVDESDMRRGRETANNLFGNAAAVLVGDFLYTRAFQLMVGSGSMRILEVMADATNIIAEGEVMQLMNIGNTDISEEEYVRVIQYKTAKLFEAAAQVGAILAGATPQQEAALRDYGMYVGTAFQIVDDILDYCGDPAEIGKNVGDDLAEGKPTLPLIYLMRQGSPEAAQDVRDALQNADRSRFAQIHAHVATSDALAYAAQQARKAVDQALACLQNLPDNEVSRAMRQLAEESLARVS
>NZ_CP022527.1|WP_009117569.1|953652_953961_-|50S-ribosomal-protein-L21
MYAVVKTGGKQYKVAVGEKLKVEQIPAELDSQIELTEVLMIADGESVKVGAPFIEGAKVTAKVVAHGRGEKIRIFKMRRRKHYQKRQGHRQNFTQIEIVAIA
>NZ_CP022527.1|WP_009426977.1|953348_953624_-|50S-ribosomal-protein-L27
MASKKAGGSTRNGRDSEAKRLGVKAYGNELIPAGSIIVRQRGTKFHAGDNVGMGKDHTLFAKVDGYVEFAVKGRLNRKTVSVRPYTGAEEA
>NZ_CP022527.1|WP_009426979.1|952984_953188_-|hypothetical-protein
MAKTGQPKDTNAPARIPFRHVFRRPPTPQMQAAPRYNAGRLKHVLPALPQPCFQTACPSFLSDTFPE
>NZ_CP022527.1|WP_009426180.1|969352_971095_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MPHAHHRLSLIFLAILSFQAALADTIEENEIRRQELRRQQEQQLQREVDVRLDDTRQSTLTPSAAESAESPCLPIHTVTLTGDAAGRFQFALKKALKETGFQSGQCLGAQGINRIMVAAQNAVIGRGYTTTRILAAPQDLNSGTLELTVLPGKVRSVRTDTSHNDQTRAARIAAFQNEIPLKGGDILNLRRIEQGLENLKRVPTAEADIQIVPADAPDESDIVVAWRQRLLPYRLSLGVDDSGSKTTGKYQGSLTFSADNPFGLSDLFYLSYGRHLGHTDAHTDSEGKKTAGGTQSYAFHYSVPAGNWLWSWNHNYYRYHQAVAGINEVYDYNGKSRGSDIGFTRLLYRDARRKSHIGFKLWQKENQSFIDDAEVEVQRRKTAGWQLSLKHKEYIGRSTLDIGLAYKRGTGMADAIAAPEEVFDEGTSRMKVITADISYNHPFQIGRQHFVYDTALHAQWNKTPLTPLDKIAIGGRYTVRGFDGESSLSAERGWYWRNEAAWSFKPAHQLYLAVDGGHVSGDSAQYLLGQTLIGAAAGLRGQFKAGGSLNYDLFAGKPIKKPKGFQTASTVFGFNLNYSF
>NZ_CP022527.1|WP_009426177.1|971530_971815_+|ribosome-assembly-RNA-binding-protein-YhbY
MSDVPDTKQILALKARAHHLHPVVMIGQHGLTEAVIKETDAALAAHELIKVRVAGDDRAERVAVAEALCGATGAFLVQHIGKLLVLWREKQDEE
>NZ_CP022527.1|WP_009426176.1|972038_972689_+|DUF4375-domain-containing-protein
MKNNDLSSLFNGFDDEDFQQMLAQMSEEERTEFKRESQQLFAEVAEMFEAFDKRVIYEKLTADILAQTPDEELVLTVFDTLAAQAPVGLSEEEYLKTLSPERRAVYALYILAGEVDNGGFNQYYYNTEAEAAAYLPEACELVGAPKYADLVRRANACYENERLAERQDGSLEAFCDSYRDNPLEKFDDEFYLLENCQALDQLLMRFIRANPQAFVG
>NZ_CP022527.1|WP_009426175.1|972826_973663_+|phosphoserine-phosphatase-SerB
MTHHLVLQHPDIARCDLPFLNGLRPSENPFPERVRRFVVEPGYVLPHEAAAALDAQRIDYAVLPAVPFADFGLIVSDMDSTLITIECVDEIAAGAGLKERVAEITERSMRGEIDFEQSLRERVGLLAGLSESVLQEVYDHVLQLSPGAEYLLAECKKHGVKFMLVSGGFTFFTDRLQTRLGLDYAFANMLETADGRLTGRLNGRIIDAEAKARLLREYREKLGLRAEQVIAVGDGANDIPMLREAGCGIAYHAKPKTQQAADLCINYGGLEALRGWFL
>NZ_CP022527.1|WP_009426173.1|973924_975871_+|RNA-polymerase-sigma-factor-RpoD
MSNPQDYEDQEDENRPLTPEEQRLRLRQLILQGKERGYITYAEINDALPDDMSDAEQIDNIVNMIQGLGIQVTEEAPDADTLLMNDSGTGMTDDDAVEEAEAALSSADSEFGRTTDPVRMYMREMGQVDLLTREDEIIIAKKIENALKNMIQAISACPGSIAEILDLIEKIRADEIKVDDVVEAILDPNEVLMHELGVSDLEIIPPGSKPSDRAAAAEEEGDGEEGDEDESSEENLESINLEELKQEVLAHFSGIGESYGLMIAALNEHNSRHPDYLKHRDAIAHKLLEVRFATRQIESLSNNLRQKVDNIRKLEREIRDICLDRVQMDRDYFISQFLPNITDLDWLEGEIGRKRVWSNALERFRHAILEKQTEVAEMEKTAQISIEELKEISKNMQSSERETARAKEEMIQANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQYLQEHGEDPDSAKLAELMEMPEEKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDVNNVAPAEAAMYSSLREVTADVLESLTPREAKVLRMRFGIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPTRSDRLKSFLDSEEGK
>NZ_CP022527.1|WP_009426172.1|976018_976162_+|hypothetical-protein
MSQEENKIKVDTYDNEQPQQKEEVELPVVDNDKGEKTESGCCGVCGG
>NZ_CP022527.1|WP_009426171.1|976290_976938_-|DedA-family-protein
MIQTLLDFVLHIDVHLAELAAQYGAWIYGLLFLIVFCETGLVVTPFLPGDSLLFAAGGIAAVGGMNVHVMVLLLFAAAVLGDAANFAVGKYFGAKLFANPDSKIFRQSHLAKTHAFYEKYGGKTIIIARFVPIVRTFAPFVAGMADMHYGRFIRYNIIGAALWVVLFSYAGYFFANIPLVKQNLSLVLAAIIVVSLLPAAIEIVRAKRAGRQSGS
>NZ_CP022527.1|WP_094030981.1|977110_977779_+|DnaA-regulatory-inactivator-Hda
MNQLIFDFARRDYPEFDKFLGSANRELVFVLQQARDQFVYVWGAAGTGKSHLLRAWAGQAAEQGADARYIDAAAMPLDDSALEADYLAVDQADRLNDGEQALLFEIFNRFRNSGRGRLLLAADVPPAQLAVREDLRTRMGYCLVYDIKPLSDDEKIAALAGMARARQIDVDDEIFRYLLNYWQRDMDSLVQMLDTLCLYTATTRRRLTLPLLRRLLTQQDAV
>NZ_CP022527.1|WP_094030982.1|977775_978453_+|HAD-family-hydrolase
MKNLAIFDLDNTLINTDSDHAWPQYLMKKGLVDVEYTRAQNDKFYRDYQNGCLDIDEFLAFHLAPLKNFSRAELDEMHREFSAEFIEPHIAPMAKMLVQSHRDAGDELLVISSTNEFIIRPICRLFGIDNVIGTQLETDADGRYTGRYVGIPSLKEGKITRLHQWLSARGESLADYGKSYFYSDSKNDLPLLRLVDEPVAVNPDAELLREAQEKGWPVLNFKEAV
>NZ_CP022527.1|WP_009426168.1|978454_978778_+|divalent-cation-tolerance-protein-CutA
MPRFKPAVVLITAPNRTEAENIGRALLKKRLAACVQYENIVSQYVWMGETCRDDEIRITVKSARSLFKKVAKTVRVRSSYDCPQILMLPVAGGSKDYLRWLKAQLAL

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Crispr_ID: NZ_CP022527_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022527_4

967919-968005

Orphan

Consensus_repeat	Method
GGCCGATGCGGCCGCTGTTGGCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022527_4

>merge|NZ_CP022527|4|967919-968005|CRISPRCasFinder
GGCCGATGCGGCCGCTGTTGGCCAGACGGGCGGTTTCAACGGTGAGATTCTGACTGCCGCTTTGGCTGATGCGGCCGCTGTTGGCCA

>NZ_CP022527|4|3|967919-968005|CRISPRCasFinder
GGCCGATGCGGCCGCTGTTGGCCA	GACGGGCGGTTTCAACGGTGAGATTCTGACTGCCGCTTT
GGCTGATGCGGCCGCTGTTGGCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022527.1\|WP_009426977.1\|953348_953624_-\|50S-ribosomal-protein-L27	unknown	unknown	gnl\|CDD\|235464
NZ_CP022527.1\|WP_094030981.1\|977110_977779_+\|DnaA-regulatory-inactivator-Hda	unknown	unknown	gnl\|CDD\|236347
NZ_CP022527.1\|WP_009426168.1\|978454_978778_+\|divalent-cation-tolerance-protein-CutA	unknown	unknown	gnl\|CDD\|376987
NZ_CP022527.1\|WP_009426176.1\|972038_972689_+\|DUF4375-domain-containing-protein	unknown	unknown	gnl\|CDD\|379547
NZ_CP022527.1\|WP_009426173.1\|973924_975871_+\|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl\|CDD\|235549
NZ_CP022527.1\|WP_094030980.1\|957198_957630_-\|transposase	unknown	unknown	gnl\|CDD\|290319
NZ_CP022527.1\|WP_009425201.1\|959537_960494_-\|immunity-49-family-protein	unknown	unknown	gnl\|CDD\|373949
NZ_CP022527.1\|WP_009426171.1\|976290_976938_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|182775
NZ_CP022527.1\|WP_009426180.1\|969352_971095_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP022527.1\|WP_009117569.1\|953652_953961_-\|50S-ribosomal-protein-L21	unknown	unknown	gnl\|CDD\|235510
NZ_CP022527.1\|WP_009426974.1\|955444_956377_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|225375
NZ_CP022527.1\|WP_009426177.1\|971530_971815_+\|ribosome-assembly-RNA-binding-protein-YhbY	unknown	unknown	gnl\|CDD\|224451
NZ_CP022527.1\|WP_009426172.1\|976018_976162_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_009426979.1\|952984_953188_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_157697513.1\|956422_957010_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_094030982.1\|977775_978453_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319796
NZ_CP022527.1\|WP_009426184.1\|957846_958095_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_009426175.1\|972826_973663_+\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NZ_CP022527.1\|WP_083479448.1\|958091_958391_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373059
NZ_CP022527.1\|WP_009426975.1\|954181_955156_+\|octaprenyl-pyrophosphate-synthetase	unknown	unknown	gnl\|CDD\|182813

Protein	Function_ID	Function_description	E-value
NZ_CP022527.1\|WP_009426977.1\|953348_953624_-\|50S-ribosomal-protein-L27	gnl\|CDD\|235464	PRK05435, rpmA, 50S ribosomal protein L27; Validated.	7.05957e-52
NZ_CP022527.1\|WP_094030981.1\|977110_977779_+\|DnaA-regulatory-inactivator-Hda	gnl\|CDD\|236347	PRK08903, PRK08903, DnaA regulatory inactivator Hda; Validated.	2.69146e-87
NZ_CP022527.1\|WP_009426168.1\|978454_978778_+\|divalent-cation-tolerance-protein-CutA	gnl\|CDD\|376987	pfam03091, CutA1, CutA1 divalent ion tolerance protein. Several gene loci with a possible involvement in cellular tolerance to copper have been identified. One such locus in eubacteria and archaebacteria, cutA, is thought to be involved in cellular tolerance to a wide variety of divalent cations other than copper. The cutA locus consists of two operons, of one and two genes. The CutA1 protein is a cytoplasmic protein, encoded by the single-gene operon and has been linked to divalent cation tolerance. It has no recognized structural motifs. This family also contains putative proteins from eukaryotes (human and Drosophila).	2.66248e-37
NZ_CP022527.1\|WP_094030982.1\|977775_978453_+\|HAD-family-hydrolase	gnl\|CDD\|319796	cd02612, HAD_PGPPase, phosphatidylglycerol-phosphate phosphatase, similar to Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C. This family includes Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C, PgpC (previously named yfhB) which catalyzes the dephosphorylation of phosphatidylglycerol-phosphate (PGP) to phosphatidylglycerol (PG). This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.85253e-63
NZ_CP022527.1\|WP_009426173.1\|973924_975871_+\|RNA-polymerase-sigma-factor-RpoD	gnl\|CDD\|235549	PRK05658, PRK05658, RNA polymerase sigma factor RpoD; Validated.	0
NZ_CP022527.1\|WP_094030980.1\|957198_957630_-\|transposase	gnl\|CDD\|290319	pfam13586, DDE_Tnp_1_2, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	7.54764e-12
NZ_CP022527.1\|WP_009425201.1\|959537_960494_-\|immunity-49-family-protein	gnl\|CDD\|373949	pfam15575, Imm49, Immunity protein 49. A predicted immunity protein with an all alpha-helical fold and a conserved proline residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Tox-REAse-1 or Tox-REase-6 families.	3.77345e-10
NZ_CP022527.1\|WP_009426171.1\|976290_976938_-\|DedA-family-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	1.37106e-111
NZ_CP022527.1\|WP_009426180.1\|969352_971095_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	1.23762e-175
NZ_CP022527.1\|WP_009117569.1\|953652_953961_-\|50S-ribosomal-protein-L21	gnl\|CDD\|235510	PRK05573, rplU, 50S ribosomal protein L21; Validated.	7.62515e-53
NZ_CP022527.1\|WP_009426974.1\|955444_956377_+\|alpha/beta-hydrolase	gnl\|CDD\|225375	COG2819, COG2819, Predicted hydrolase of the alpha/beta superfamily [General function prediction only].	4.7542e-49
NZ_CP022527.1\|WP_009426176.1\|972038_972689_+\|DUF4375-domain-containing-protein	gnl\|CDD\|379547	pfam14300, DUF4375, Domain of unknown function (DUF4375). This family of proteins is found in bacteria. Proteins in this family are typically between 156 and 204 amino acids in length. There is a single completely conserved residue G that may be functionally important.	9.248e-14
NZ_CP022527.1\|WP_009426177.1\|971530_971815_+\|ribosome-assembly-RNA-binding-protein-YhbY	gnl\|CDD\|224451	COG1534, COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis].	3.56806e-34
NZ_CP022527.1\|WP_009426175.1\|972826_973663_+\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.15176e-99
NZ_CP022527.1\|WP_083479448.1\|958091_958391_-\|hypothetical-protein	gnl\|CDD\|373059	pfam14424, Toxin-deaminase, The BURPS668_1122 family of deaminases. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Burkholderia BURPS668_1122. Members of this family are found as toxins in polymorphic toxin systems in a wide range of bacteria and in the eukaryote Perkinsus. Members of this family typically possess a DxE catalytic motif in Helix-2 of the core fold instead of the more common C[H]xE motif. The Perkinsus versions are predicted to be inactive.	7.43332e-13
NZ_CP022527.1\|WP_009426975.1\|954181_955156_+\|octaprenyl-pyrophosphate-synthetase	gnl\|CDD\|182813	PRK10888, PRK10888, octaprenyl diphosphate synthase; Provisional.	8.32688e-133

>NZ_CP022527.1|WP_009425201.1|959537_960494_-|immunity-49-family-protein
MSFMCSKKWYDHISSIVIEYAESFNQYLSGKGDPDIAYHLSYIDERKGSPFAAMSNLQRRVYAACAHALWAERDLPKFKRYAYQLGKLEILSSMGWSYPEPFFLCAETPNVANPLFVMLMSDSPKIRSFLLRNIDLISNDTEEFADRYDLNRQLKYNTLLMLEGTQLERLERRSLNVLENQQQSKWLQLRCEDFLFFLAFARQDPAAMRQALDPLFEKKRARQAAKETLSYFDFFLQPQIVMYAKIAAIHGFDLGIDHEIAPKEAIAYAPLPEGEYQDPFDFMRTYDLDFPYEYLQNWVDYYTGQTDTLGLPPLVNDE
>NZ_CP022527.1|WP_083479448.1|958091_958391_-|hypothetical-protein
MWRSSSLDRVTNEPKIFTATEVKGKNGNAWLRHTDSEYRMLNDLAYKLGGKPGHVYHQVYGHLTIVSEYPYCTSCTHVIQQFQTMFPNLRLTLINGVKK
>NZ_CP022527.1|WP_009426184.1|957846_958095_-|hypothetical-protein
MINKKLEFKVLVMDLDILEKAVEMYNLDPTSNVKFQIINEIEDSLNSATIQSDKYNIEEVFRLGYRLADLENYLQNKGEFDW
>NZ_CP022527.1|WP_094030980.1|957198_957630_-|transposase
MVLSVGKQLAVINAVVGKSAYIQHIIAAQTIRIELLPGQRNDICGVLSLIKDKSFGALFADKAFDADWLIKELTQKGIEPVIPPRKGRNTERCYDRGKYKWRHLIENFFCRIKEFKKIAMRCEKTDESFAANIYLAATVLRLA
>NZ_CP022527.1|WP_157697513.1|956422_957010_+|hypothetical-protein
MFFRITNHPHSKRFTALHIKRSSESFNFVEASLSDGLYYRFDDGSGCGAAVARRMLEYEELYKKRLEKHKKIIQKQVEINHGQIIRHHEIQQFFHNLHLAFIHMLSSQASERALSAFNDTVVANTSIEKLKKVEWMMSSEMHKEYEETLPLLKNEMNASKHAFWHKKSPEEQEKFAKIFKQNKVVINAMAKNEDG
>NZ_CP022527.1|WP_009426974.1|955444_956377_+|alpha/beta-hydrolase
MKTLITALALLPALAAAAPSSSPNNEITRPADLSALTAPHSGYTFQTLAFQDQNGRAYRVFLGIPDSPPPAAGYPVLYALDGNALPEYLAAPALQDLSANPPVLVLIGYPTDLRFDTTRRAYDYTPPDLSGNSLPDQLMDGRRNGGAPALLELIDGKIRPAVERAAHTDPARQALWGHSYGGLFVLYTLFQRPQTFTRYIAADPALWWQNGLMLRYAERAAAKADAYSGRSLLLEKSGKAHHKQPADAKQADMLAKRAAVIASVPADAGEKLVAKLRGQGLAAEYRHYPDLTHGGLLGISFKQALPAAAR
>NZ_CP022527.1|WP_009426975.1|954181_955156_+|octaprenyl-pyrophosphate-synthetase
MLEHLPYFQQNLAADLGRVNQVVERAVQSEVALISQIGNYIIGAGGKRLRPIITILAGKSLGYDDDKLYSLAAMVEFIHTSTLLHDDVVDESDMRRGRETANNLFGNAAAVLVGDFLYTRAFQLMVGSGSMRILEVMADATNIIAEGEVMQLMNIGNTDISEEEYVRVIQYKTAKLFEAAAQVGAILAGATPQQEAALRDYGMYVGTAFQIVDDILDYCGDPAEIGKNVGDDLAEGKPTLPLIYLMRQGSPEAAQDVRDALQNADRSRFAQIHAHVATSDALAYAAQQARKAVDQALACLQNLPDNEVSRAMRQLAEESLARVS
>NZ_CP022527.1|WP_009117569.1|953652_953961_-|50S-ribosomal-protein-L21
MYAVVKTGGKQYKVAVGEKLKVEQIPAELDSQIELTEVLMIADGESVKVGAPFIEGAKVTAKVVAHGRGEKIRIFKMRRRKHYQKRQGHRQNFTQIEIVAIA
>NZ_CP022527.1|WP_009426977.1|953348_953624_-|50S-ribosomal-protein-L27
MASKKAGGSTRNGRDSEAKRLGVKAYGNELIPAGSIIVRQRGTKFHAGDNVGMGKDHTLFAKVDGYVEFAVKGRLNRKTVSVRPYTGAEEA
>NZ_CP022527.1|WP_009426979.1|952984_953188_-|hypothetical-protein
MAKTGQPKDTNAPARIPFRHVFRRPPTPQMQAAPRYNAGRLKHVLPALPQPCFQTACPSFLSDTFPE
>NZ_CP022527.1|WP_009426180.1|969352_971095_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MPHAHHRLSLIFLAILSFQAALADTIEENEIRRQELRRQQEQQLQREVDVRLDDTRQSTLTPSAAESAESPCLPIHTVTLTGDAAGRFQFALKKALKETGFQSGQCLGAQGINRIMVAAQNAVIGRGYTTTRILAAPQDLNSGTLELTVLPGKVRSVRTDTSHNDQTRAARIAAFQNEIPLKGGDILNLRRIEQGLENLKRVPTAEADIQIVPADAPDESDIVVAWRQRLLPYRLSLGVDDSGSKTTGKYQGSLTFSADNPFGLSDLFYLSYGRHLGHTDAHTDSEGKKTAGGTQSYAFHYSVPAGNWLWSWNHNYYRYHQAVAGINEVYDYNGKSRGSDIGFTRLLYRDARRKSHIGFKLWQKENQSFIDDAEVEVQRRKTAGWQLSLKHKEYIGRSTLDIGLAYKRGTGMADAIAAPEEVFDEGTSRMKVITADISYNHPFQIGRQHFVYDTALHAQWNKTPLTPLDKIAIGGRYTVRGFDGESSLSAERGWYWRNEAAWSFKPAHQLYLAVDGGHVSGDSAQYLLGQTLIGAAAGLRGQFKAGGSLNYDLFAGKPIKKPKGFQTASTVFGFNLNYSF
>NZ_CP022527.1|WP_009426177.1|971530_971815_+|ribosome-assembly-RNA-binding-protein-YhbY
MSDVPDTKQILALKARAHHLHPVVMIGQHGLTEAVIKETDAALAAHELIKVRVAGDDRAERVAVAEALCGATGAFLVQHIGKLLVLWREKQDEE
>NZ_CP022527.1|WP_009426176.1|972038_972689_+|DUF4375-domain-containing-protein
MKNNDLSSLFNGFDDEDFQQMLAQMSEEERTEFKRESQQLFAEVAEMFEAFDKRVIYEKLTADILAQTPDEELVLTVFDTLAAQAPVGLSEEEYLKTLSPERRAVYALYILAGEVDNGGFNQYYYNTEAEAAAYLPEACELVGAPKYADLVRRANACYENERLAERQDGSLEAFCDSYRDNPLEKFDDEFYLLENCQALDQLLMRFIRANPQAFVG
>NZ_CP022527.1|WP_009426175.1|972826_973663_+|phosphoserine-phosphatase-SerB
MTHHLVLQHPDIARCDLPFLNGLRPSENPFPERVRRFVVEPGYVLPHEAAAALDAQRIDYAVLPAVPFADFGLIVSDMDSTLITIECVDEIAAGAGLKERVAEITERSMRGEIDFEQSLRERVGLLAGLSESVLQEVYDHVLQLSPGAEYLLAECKKHGVKFMLVSGGFTFFTDRLQTRLGLDYAFANMLETADGRLTGRLNGRIIDAEAKARLLREYREKLGLRAEQVIAVGDGANDIPMLREAGCGIAYHAKPKTQQAADLCINYGGLEALRGWFL
>NZ_CP022527.1|WP_009426173.1|973924_975871_+|RNA-polymerase-sigma-factor-RpoD
MSNPQDYEDQEDENRPLTPEEQRLRLRQLILQGKERGYITYAEINDALPDDMSDAEQIDNIVNMIQGLGIQVTEEAPDADTLLMNDSGTGMTDDDAVEEAEAALSSADSEFGRTTDPVRMYMREMGQVDLLTREDEIIIAKKIENALKNMIQAISACPGSIAEILDLIEKIRADEIKVDDVVEAILDPNEVLMHELGVSDLEIIPPGSKPSDRAAAAEEEGDGEEGDEDESSEENLESINLEELKQEVLAHFSGIGESYGLMIAALNEHNSRHPDYLKHRDAIAHKLLEVRFATRQIESLSNNLRQKVDNIRKLEREIRDICLDRVQMDRDYFISQFLPNITDLDWLEGEIGRKRVWSNALERFRHAILEKQTEVAEMEKTAQISIEELKEISKNMQSSERETARAKEEMIQANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQYLQEHGEDPDSAKLAELMEMPEEKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDVNNVAPAEAAMYSSLREVTADVLESLTPREAKVLRMRFGIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPTRSDRLKSFLDSEEGK
>NZ_CP022527.1|WP_009426172.1|976018_976162_+|hypothetical-protein
MSQEENKIKVDTYDNEQPQQKEEVELPVVDNDKGEKTESGCCGVCGG
>NZ_CP022527.1|WP_009426171.1|976290_976938_-|DedA-family-protein
MIQTLLDFVLHIDVHLAELAAQYGAWIYGLLFLIVFCETGLVVTPFLPGDSLLFAAGGIAAVGGMNVHVMVLLLFAAAVLGDAANFAVGKYFGAKLFANPDSKIFRQSHLAKTHAFYEKYGGKTIIIARFVPIVRTFAPFVAGMADMHYGRFIRYNIIGAALWVVLFSYAGYFFANIPLVKQNLSLVLAAIIVVSLLPAAIEIVRAKRAGRQSGS
>NZ_CP022527.1|WP_094030981.1|977110_977779_+|DnaA-regulatory-inactivator-Hda
MNQLIFDFARRDYPEFDKFLGSANRELVFVLQQARDQFVYVWGAAGTGKSHLLRAWAGQAAEQGADARYIDAAAMPLDDSALEADYLAVDQADRLNDGEQALLFEIFNRFRNSGRGRLLLAADVPPAQLAVREDLRTRMGYCLVYDIKPLSDDEKIAALAGMARARQIDVDDEIFRYLLNYWQRDMDSLVQMLDTLCLYTATTRRRLTLPLLRRLLTQQDAV
>NZ_CP022527.1|WP_094030982.1|977775_978453_+|HAD-family-hydrolase
MKNLAIFDLDNTLINTDSDHAWPQYLMKKGLVDVEYTRAQNDKFYRDYQNGCLDIDEFLAFHLAPLKNFSRAELDEMHREFSAEFIEPHIAPMAKMLVQSHRDAGDELLVISSTNEFIIRPICRLFGIDNVIGTQLETDADGRYTGRYVGIPSLKEGKITRLHQWLSARGESLADYGKSYFYSDSKNDLPLLRLVDEPVAVNPDAELLREAQEKGWPVLNFKEAV
>NZ_CP022527.1|WP_009426168.1|978454_978778_+|divalent-cation-tolerance-protein-CutA
MPRFKPAVVLITAPNRTEAENIGRALLKKRLAACVQYENIVSQYVWMGETCRDDEIRITVKSARSLFKKVAKTVRVRSSYDCPQILMLPVAGGSKDYLRWLKAQLAL

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Crispr_ID: NZ_CP022527_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022527_5

1241977-1242073

Orphan

Consensus_repeat	Method
GTAGGTTGGGTTGCAAACCCAACAAAATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022527_5

>merge|NZ_CP022527|5|1241977-1242073|CRISPRCasFinder
GTAGGTTGGGTTGCAAACCCAACAAAATGTTGGAACCGCAAACATTGTCGAGTCTCGACCCAAGTAGGGTAGGTTGGGTTGCAAACCCAACAAAATG

>NZ_CP022527|5|4|1241977-1242073|CRISPRCasFinder
GTAGGTTGGGTTGCAAACCCAACAAAATG	TTGGAACCGCAAACATTGTCGAGTCTCGACCCAAGTAGG
GTAGGTTGGGTTGCAAACCCAACAAAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022527.1\|WP_036496429.1\|1254288_1254945_+\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|225462
NZ_CP022527.1\|WP_009426772.1\|1252258_1253128_-\|DUF808-domain-containing-protein	unknown	unknown	gnl\|CDD\|377542
NZ_CP022527.1\|WP_009427131.1\|1246238_1246889_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376175
NZ_CP022527.1\|WP_009427127.1\|1243194_1245225_+\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
NZ_CP022527.1\|WP_036496584.1\|1238513_1238909_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP022527.1\|WP_009426773.1\|1253236_1254130_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP022527.1\|WP_009427120.1\|1240534_1240894_+\|EthD-domain-containing-protein	unknown	unknown	gnl\|CDD\|369213
NZ_CP022527.1\|WP_009427121.1\|1240967_1241633_+\|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl\|CDD\|235844
NZ_CP022527.1\|WP_094031029.1\|1235124_1237383_+\|NADH-quinone-oxidoreductase-subunit-G	unknown	unknown	gnl\|CDD\|236386
NZ_CP022527.1\|WP_009426771.1\|1251398_1252202_-\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143596
NZ_CP022527.1\|WP_094031030.1\|1248511_1249957_+\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP022527.1\|WP_036496582.1\|1232821_1233007_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_094031213.1\|1245590_1245860_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NZ_CP022527.1\|WP_009427119.1\|1239890_1240448_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|376808
NZ_CP022527.1\|WP_009427111.1\|1233380_1234676_+\|NADH-quinone-oxidoreductase-subunit-NuoF	unknown	unknown	gnl\|CDD\|131014
NZ_CP022527.1\|WP_009427132.1\|1247002_1248502_+\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP022527.1\|WP_009427114.1\|1237386_1238457_+\|NADH-quinone-oxidoreductase-subunit-NuoH	unknown	unknown	gnl\|CDD\|235692
NZ_CP022527.1\|WP_009427122.1\|1241629_1241935_+\|NADH-quinone-oxidoreductase-subunit-NuoK	unknown	unknown	gnl\|CDD\|180218
NZ_CP022527.1\|WP_009427116.1\|1239007_1239487_+\|NADH-quinone-oxidoreductase-subunit-NuoI	unknown	unknown	gnl\|CDD\|235637
NZ_CP022527.1\|WP_009427125.1\|1242284_1242701_+\|GFA-family-protein	unknown	unknown	gnl\|CDD\|226314

Protein	Function_ID	Function_description	E-value
NZ_CP022527.1\|WP_036496429.1\|1254288_1254945_+\|NAD(P)H-binding-protein	gnl\|CDD\|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	1.58274e-60
NZ_CP022527.1\|WP_009426772.1\|1252258_1253128_-\|DUF808-domain-containing-protein	gnl\|CDD\|377542	pfam05661, DUF808, Protein of unknown function (DUF808). This family consists of several bacterial proteins of unknown function.	2.16863e-116
NZ_CP022527.1\|WP_009427131.1\|1246238_1246889_+\|hypothetical-protein	gnl\|CDD\|376175	pfam18753, Nmad2, Nucleotide modification associated domain 2. A beta-strand rich domain containing a conserved cysteine and charged residues predicted to play a role in modified DNA base biosynthesis.	6.7243e-63
NZ_CP022527.1\|WP_009427119.1\|1239890_1240448_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|376808	pfam02525, Flavodoxin_2, Flavodoxin-like fold. This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.	5.5093e-46
NZ_CP022527.1\|WP_036496584.1\|1238513_1238909_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.45806e-11
NZ_CP022527.1\|WP_009426773.1\|1253236_1254130_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.18194e-46
NZ_CP022527.1\|WP_009427120.1\|1240534_1240894_+\|EthD-domain-containing-protein	gnl\|CDD\|369213	pfam07110, EthD, EthD domain. This family consists of several bacterial sequences which are related to the EthD protein of Rhodococcus ruber. In Rhodococcus ruber, EthD is thought to be involved in the degradation of ethyl tert-butyl ether (ETBE). EthD synthesis is induced by ETBE but it's exact function is unknown, it is however thought to be essential to the ETBE degradation system.	1.38768e-12
NZ_CP022527.1\|WP_009427121.1\|1240967_1241633_+\|NADH-quinone-oxidoreductase-subunit-J	gnl\|CDD\|235844	PRK06638, PRK06638, NADH-quinone oxidoreductase subunit J.	5.22993e-57
NZ_CP022527.1\|WP_094031029.1\|1235124_1237383_+\|NADH-quinone-oxidoreductase-subunit-G	gnl\|CDD\|236386	PRK09129, PRK09129, NADH dehydrogenase subunit G; Validated.	0
NZ_CP022527.1\|WP_009426771.1\|1251398_1252202_-\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143596	cd07572, nit, Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases). This subgroup includes mammalian Nit1 and Nit2, the Nit1-like domain of the invertebrate NitFhit, and various uncharacterized bacterial and archaeal Nit-like proteins. Nit1 and Nit2 are candidate tumor suppressor proteins. In NitFhit, the Nit1-like domain is encoded as a fusion protein with the non-homologous tumor suppressor, fragile histidine triad (Fhit). Mammalian Nit1 and Fhit may affect distinct signal pathways, and both may participate in DNA damage-induced apoptosis. Nit1 is a negative regulator in T cells. Overexpression of Nit2 in HeLa cells leads to a suppression of cell growth through cell cycle arrest in G2. These Nit proteins and the Nit1-like domain of NitFhit belong to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 10.	4.0772e-130
NZ_CP022527.1\|WP_094031030.1\|1248511_1249957_+\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	4.59097e-169
NZ_CP022527.1\|WP_094031213.1\|1245590_1245860_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	6.6639e-42
NZ_CP022527.1\|WP_009427127.1\|1243194_1245225_+\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP022527.1\|WP_009427111.1\|1233380_1234676_+\|NADH-quinone-oxidoreductase-subunit-NuoF	gnl\|CDD\|131014	TIGR01959, NADH-quinone_oxidoreductase_subunit_F, NADH-quinone oxidoreductase, F subunit. This model describes the F chain of complexes that resemble NADH-quinone oxidoreductases. The electron acceptor is a quinone, ubiquinone, in mitochondria and most bacteria, including Escherichia coli, where the recommended gene symbol is nuoF. This family does not have any members in chloroplast or cyanobacteria, where the quinone may be plastoquinone and NADH may be replaced by NADPH, nor in Methanosarcina, where NADH is replaced by F420H2. [Energy metabolism, Electron transport].	0
NZ_CP022527.1\|WP_009427132.1\|1247002_1248502_+\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	0
NZ_CP022527.1\|WP_009427114.1\|1237386_1238457_+\|NADH-quinone-oxidoreductase-subunit-NuoH	gnl\|CDD\|235692	PRK06076, PRK06076, NADH-quinone oxidoreductase subunit NuoH.	1.62907e-142
NZ_CP022527.1\|WP_009427122.1\|1241629_1241935_+\|NADH-quinone-oxidoreductase-subunit-NuoK	gnl\|CDD\|180218	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK.	2.71853e-40
NZ_CP022527.1\|WP_009427116.1\|1239007_1239487_+\|NADH-quinone-oxidoreductase-subunit-NuoI	gnl\|CDD\|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	2.3605e-88
NZ_CP022527.1\|WP_009427125.1\|1242284_1242701_+\|GFA-family-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	2.55787e-25

>NZ_CP022527.1|WP_009427122.1|1241629_1241935_+|NADH-quinone-oxidoreductase-subunit-NuoK
MITLTHYLVLAALLFGISAMGIFMNRKNVLVLLMSIELMLLAVNFNFIAFSQYLGDTAGQIFVFFVLTVAAAESAIGLAIMVLVFRNRQSINISDLDSLKG
>NZ_CP022527.1|WP_009427121.1|1240967_1241633_+|NADH-quinone-oxidoreductase-subunit-J
MSFQLIMFYTLAAIILFGALKTVTAKNPVHAALYLVLTFCMSAMMWMLMQAEFLGITLVVVYVGAVMVLFLFVVMMLNIDIEEMRKGFWRNAPAALTVGVLMAVALILILVSPKTNLAAFGPMNDIPADYSNVRDLGSQIYTTYLLPFELAAVLLVLGMVAAIALVHRKSSNPKRIDPADQVKVDAKQGRLRMVKMAAVVQTPSAPAAEETDDAADSENKA
>NZ_CP022527.1|WP_009427120.1|1240534_1240894_+|EthD-domain-containing-protein
MFKIIMLVKKKTELDTEAFIARWQQHSEKVLGLKDVLNIRHYAKTLPFQAGAQPATQRGTLPFAFDAMGELWYDSRDDFQRARETEAGQAALAALREDEAEFVDLQHSVMWFGEEERVI
>NZ_CP022527.1|WP_009427119.1|1239890_1240448_+|NAD(P)H-dependent-oxidoreductase
MSKTLVIVAHPSIAQSAVNKRWLAQLRRYPERFTVHELYATYPDGKIDIAAEQRLADAHQALVLQFPVYWFNCPPLLKQWLDDVLTYGWAYGSQGKALAGKKTAIAVSLGTPAADYTREGAVGCTVAEALRPFELSLRYCNADYRPMFAFHTIDSNAGYTEAALQAIEQSAADYVAWLDALAQAA
>NZ_CP022527.1|WP_009427116.1|1239007_1239487_+|NADH-quinone-oxidoreductase-subunit-NuoI
MANLVKTFLLGELVKGMGLTLKNFFARKETIYFPEEKTPQSVRFRGLHAQRRYPNGEERCIACKLCEAVCPAMAINIESEEREDGTRRTTRYDIDLTKCIFCGFCEEACPTDAIVETHIFEYHGEKKGDLHFTKPMLLAIGDKYEEEIAKRKAADAPYR
>NZ_CP022527.1|WP_036496584.1|1238513_1238909_+|GNAT-family-N-acetyltransferase
MIEYSNSKTITAEQFAGVLERSGIRRPTTDLPRLQTMLDQADILWTAWDGANLVGVARSLTDFAYACYLSDLAVDTACQHQGIGRELVRRTQAQIGEKVALILLSAPAAMDYYPKIGFEKAENAFIVKRTA
>NZ_CP022527.1|WP_009427114.1|1237386_1238457_+|NADH-quinone-oxidoreductase-subunit-NuoH
MQEWFQTLFSGWLGPIGSDIGLIVAIVVKIVIILIPLILTVAYLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFKLLFKEVTRPKLSNKALFYIGPIMSLAPSFAAWAVIPFSEKWLLTNINVGLLYILMITSLSVYGVIIAGWASNSKYSFLGAMRSSAQTISYEIAMGAALLCVVMVSGSLNFSEIVAAQAQGIAGGSVFSWNWLPLFPVFIIYLISAVAETNRAPFDVAEGESEIVAGFHVEYSGFAFALFFLAEYIFMILIAALTSLMFLGGWLSPFPQSWGAVGTPSAFWMFGKMAMVLYGYLWIRATFPRYRYDQIMRLGWKVLIPISFVFIVVLALWMVSPLSLWK
>NZ_CP022527.1|WP_094031029.1|1235124_1237383_+|NADH-quinone-oxidoreductase-subunit-G
MLQIEIDGKQVSVEQGATVIEAAQKLGTYIPHFCYHKKLSIAANCRMCLVEVEKAPKPLPACATPVTDGMVVRTHSEKARQAQEGVMEFLLINHPLDCPVCDKGGECQLQDLAMGYGKTTSRYTEAKRAVVGKDMGPLISAAEMSRCIHCTRCVRFTEEIAGEQEIAMAYRGEFSEIMPFVGKVVETELSGNVIDLCPVGALTSKPFRFNARTWELSRRKSVSAHDSLGSNLIVQVKEHTVRRVLPLENEAINECWLSDRDRFAYEGLYHESRLKNPKIKQGGEWIDVDWKTALEYVRTSLDCVGKDGQQDQIGIWANPMNTVEELYLAKKLAQGLGIKHFDTRLQAQDSRLQGSLKGAQWLGQSIEDLGNAGAILVLGANLRKEQPLLTARLRRAANNGSQISVLASSKEALHMPLAAQQILHPNQWAGCLKTLAQDLENGIGGSLKTAEQAAIVLGAEAQNHPDYAAIYAAAQELADATGAKLGILPQAANSVGADVLAVNNGQTIAEMIAQPKKAVLLLNVEPEIDVANGGRAVAALREAQTVMAFTPYVSDTLLDVCDLLLPIAPFTETSGSLINMEGRLQSFHGVSKGYGDSRPLWKILRVLGNIFEVDGFEFDSSEEVLQEAIDKDALAGKLDNRSSWQGAAAPAGSGLTRVGGTGIYHTDAIVRRAESLQQTGHAQVPAARVHPLTLAALGLLDGDSVRAKHGAHSVTVSVSADKTLPENIVHLPLHSANAELGGMMNAIELERA
>NZ_CP022527.1|WP_009427111.1|1233380_1234676_+|NADH-quinone-oxidoreductase-subunit-NuoF
MAIYQTGVIFDNVDTRDPDCWTLDSYLQRGGYQALRKILSENTSQDDVIAEVKASGLRGRGGAGFPTGLKWSFMPRSFPGTKYVVCNTDEGEPGTFKDRDIIFFNPHALIEGMIIAGYAMGAPAGYNYIHGEIFEGYQRFEAALAQARAAGYLGQNILGSEFSFELYAAHGYGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTETFSSVPFIIRDGGQTFADKGIENAGGTKLFSISGHIERPGNYEVPLGTPFAKILEMAGGMKNGKKLKAVIPGGSSAPVLPADIMMELNMDYDSIAKAGSMLGSGAIIVMDEDVCMVKALERLSYFYHEESCGQCTPCREGTGWLYRIVHRIANGQGRMEDLDLLDSVGNNMAGRTICALADAAVFPVRSFTKHFRDEFVHYIEHGRPMKEHKWC
>NZ_CP022527.1|WP_036496582.1|1232821_1233007_+|hypothetical-protein
MKPLLFVSAAALLMSGCASVEEYFNGTSPHTCYGLGNPECVRQGYHPGGGIMQPGATAYEQ
>NZ_CP022527.1|WP_009427125.1|1242284_1242701_+|GFA-family-protein
MKAQCQCGSVTLEVRHNHEVHACHCSKCRQRTGGASFTLTAEGAPQISGEENIGRYRSSDWGERTFCKQCGNDLYFHLLPESGMDEAWYVNAGLFADNADFALKLQIFTDCQAPYYHLSDDTPKMTEQEFLAWVGAAE
>NZ_CP022527.1|WP_009427127.1|1243194_1245225_+|NADH-quinone-oxidoreductase-subunit-L
MTDMTLYLTIALLPLAGSLLAGLFGNKIGRAGAHSVTILGVAVSAVLSGWVLWGFIDGSRAKFDENVYTWLTMGGIDFSVGFLVDSMTAMMMAVVTGVSLMVHIYTIGYMHDEAVGYQRFFSYISLFTFSMLMLIMSNNFIQLFFGWEAVGLVSYLLIGFYFKKPSATFANLKAFLVNRVGDFGFVLGIALVLAYFGGSLRYADVFAYLPQVQNATIELIPGVQWSLVTVTCLLLFVGAMGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGLFMVSRMSPIYELSSTALSVIMVIGAITALFMGFLGTIQNDIKRVVAYSTLSQLGYMTVALGASAYSVAMFHVMTHAFFKALLFLAAGSAIIGMHHDQDMRHMGNLKKYMPVTWLTMLLGNLALIGTPFFSGFYSKDSIIEAAKLSNLPGSGFAYFAVLASVFVTAFYAFRQYFMVFHGKEKWRELPEHHDDHHSDGHHHGLGKHDNPHESPWVVTLPLVLLAIPSVIIGYIAIEPMLYGDFFKGVIFVNHEAHPTMHLMKEEFHGALAMVSHSLHSPVLYLAIAGVVSAWVLYIKAPGLPAKIAAAFRPVYVLFENKYYLDTIYYNVFAKGSRALGTFFWKAIDTAIIDNGLVNGSAKLVGAVSAQVRKMQTGFIYTYAAFMVTGVLVLIVAFFWGLWFG
>NZ_CP022527.1|WP_094031213.1|1245590_1245860_+|GIY-YIG-nuclease-family-protein
MASGRNGVLYIGVTMNLPERVWQHKNSLDFDNFTARYNVHDLVWYELFEHMPAAIAKEKALKKWRREWKIRLIEEQNPEWLDLFAGLIR
>NZ_CP022527.1|WP_009427131.1|1246238_1246889_+|hypothetical-protein
MKLTSYVVKHDTGFAPNPYYGFLTLATCKPKIRQSANIGDILVGTGSARGVGNNKIIYVGVVSEVLSTIDYSIDPRFEAKKPSNQDEKAKRGDNIYYWQDGQWQQIKNISHGKGEIYDDLQPNRILVCEKFWYLGNQAKMIPEEFLEIVKIGPGHKNTIDETLINDFMKWIGQFPRGVMGEPSSLSFCSSDKIPACAGMTAVEATPFSDGLKSSLK
>NZ_CP022527.1|WP_009427132.1|1247002_1248502_+|NADH-quinone-oxidoreductase-subunit-M
MFSNNLLSLAIWVPIAAGILVLATGSDRRALLARILALIGAAAGFLVTLPLFTRFDRLSGGFQFQEFHQWIPTLNINYALGVDGISVLFVILNAFITLMVVLAGWEVIQKRPAQYMAAFLIMSGLINGAFAAQDALLFYVFFEGMLIPLYLIIGVWGGPRRVYASVKLFLYTLMGSLLMLVAMVYLSYQAGGSFAIADFQNLKQIPLGIQQILFVAFFLSFAVKVPMWPVHTWLPDAHVEAPTGGSMVLAAITLKVGAYGFLRFILPILPDAARFFAPAIVALSLIAVIYIGMVALVQTDMKKLVAYSSISHMGFVTLGMFLFLDGRLNDWALKGAIMQMISHGFVSAAMFMCIGVMYDRLHTRNIADYGGVVNVMPKFAAFMMLFGMANAGLPATSGFVGEFMVIMGSVEVNFWVGALAALTLIYGASYTLWMYKRVIFGAITNPHVAEMKDINAREFLILAVLAATVLGMGLWPEPFIAVVHQAANDLITQVAQSKI
>NZ_CP022527.1|WP_094031030.1|1248511_1249957_+|NADH-quinone-oxidoreductase-subunit-NuoN
MNTNSLNLLPALPEIVLLCGLFSVLLIDLWLKDGQRRVTHYLSLLVLALAAAAQCYVWTPVAVSIFSDMYLSDGLSQLAKLTMYAALAAAFVYAAPYNRVRSIFGGEFYTLSLFGLTGMSMMASAGHFLVAYIGLELLSLSLYAMIALRRDSARSAEAALKYFVLGALASGLLLYGVSMIYGATGSLNFATILANSYSGLDQPWLMKLGLIFVVVGIAFKLGAVPFHMWVPDVYEGAPTSVAAIVGSAPKMAAAVFAARILYGAMDNEHADWTQMLAVIAVASLLVGNLAAIMQTNLKRMLAYSTVSHMGFVLLAFLGGSISFSAGLYYALTYVATALVGFGVLMQLSDETADCETIADLAGLNQRNAWYAFLMLLTMFSMAGIPPLVGFYAKLQVIQLLVGKGYLWLAVFAVVMSLIGAFYYLRVVRTIYFDEPQNVRIRPGSAVAKAVLSANALLLLLWGILPQSVMDWCVQAVQTAAG
>NZ_CP022527.1|WP_009426771.1|1251398_1252202_-|carbon-nitrogen-hydrolase-family-protein
MEKIRAAVVQMVSSADPAANIRAMRRLVRQAADAGAGWVLLPEYWPLMGHADTDKLALAEPFGAGRFQTALAEAAAECGVVLFGGTIPLHSGEAGKVLNSMPVYGRDGTLLGRYDKMHLFGYSGLGERYAEADTIAAGGSVPKLAADGWPLAQGICYDLRFPEFFRAQAPFAALLLPAAFTYTTGKAHWELLLRARAVENQCYVLAAGQGGTHESGRRTFGHSMIVDPWGDILAVLPEGEGVIAADLDPVRLNSVRTRLPALAHRVL
>NZ_CP022527.1|WP_009426772.1|1252258_1253128_-|DUF808-domain-containing-protein
MAFASLFTLLDDIASVLDDVSLITKAAAKKTVGVVGDDLALNAGQVTGVSAERELPVVWRVAKGSLANKLILIPAALLLSWLLPALITPLLMLGGLFLCFEGVEKLLHKFFRRPAAGHSPQAVPDELDSEEAKIKGAIRTDFILSAEIIIIALGTVGAGAPLLDRTLALLLIGVGMTVFVYGLVAVIVKLDDLGLFFIRRGGALKGLGHGLIALMPWLMRGLSVAGTLAVFLVGGGLIAHNLPVLADFLHHVGIHDGLAGAIAAMAVGLLAGAAACAVVLPLMKLFGRH
>NZ_CP022527.1|WP_009426773.1|1253236_1254130_-|LysR-family-transcriptional-regulator
MQEIKSLLTFATLLECGTMSSAAEKLDMTPSAVSQHISRLESTYGVKLLNRSTRSLTPTDAGRALADSCRRLLRCTEEAFATLGQVNTDVGGSIKITLPSAMAAHPALHRSLRRLLRDHPAVRPQLLFGDGLIDLQRGDADIALRGGEHALDDENLVARLLTRQRWLICASPDYLAEHPVAAPQDLASCRWLRYLPARLTMRRGTDFFELDTSQGIYCGQLNALAELAKAGLGLALFLDGDIAADLAEGRLKTVLPDWTLPSVDVYAVTPYRIQSARTQAVLDILLQEFDKEGEKAV
>NZ_CP022527.1|WP_036496429.1|1254288_1254945_+|NAD(P)H-binding-protein
MKIAVIGATGLVGNAVVQELAQRGHSVTAFARNTGTVFQAANVDAVAADVNASDFAAQLKGFDAVVSAFNPGWDNPNLAADFTRGADSIVAAAQAAQVPYLLVIGGAGSLNVAPGLQLVDTPDFPADVYPGANAARELLNRLRERRDVNWAFLSPAAMFAVNPVKFEKTGAYRIGADDVLLNADGSPADIALPDLAAAIADDAENKAHLFKRFTVAEK

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Crispr_ID: NZ_CP022527_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022527_6

1852962-1853122

Orphan

Consensus_repeat	Method
AGCCGCCCCGTTTGTTTTCAGACGGCCTCCGC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP022527_6

>merge|NZ_CP022527|6|1852962-1853122|PILER-CR
GCGGAGGCCGTCTGAACTGAGGAACGGAGCTTTCAGACGGCTTCTTGCATCTGAATAAGGCCGTCTGAAAACAGGCGGGTCGGCTGGGCATATTTGTCCTGCGCTTGGGAAAGGGCAGGGCAACGGTATGCGGAGGCCGTCTGAAAACAAATGGGGCGGCT

>NZ_CP022527|6|3|1852962-1853122|PILER-CR
GCGGAGGCCGTCTGAACTGAGGAACGGAGCTT	TCAGACGGCTTCTTGCATCTGAATAAGGCCGTCTGAAAACA
GGCGGGTCGGCTGGGCATATTTGTCCTGCGCT	TGGGAAAGGGCAGGGCAACGGTATGCGGAGGCCGTCTGAAAACA
AATGGGGCGGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022527.1\|WP_009426924.1\|1861690_1862326_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|225496
NZ_CP022527.1\|WP_009426913.1\|1852185_1852944_-\|TatD-family-hydrolase	unknown	unknown	gnl\|CDD\|223162
NZ_CP022527.1\|WP_009426916.1\|1855144_1856836_-\|D-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|236872
NZ_CP022527.1\|WP_009426910.1\|1849199_1850390_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238208
NZ_CP022527.1\|WP_094031132.1\|1846553_1849076_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224422
NZ_CP022527.1\|WP_009426915.1\|1854107_1855010_-\|Dyp-type-peroxidase	unknown	unknown	gnl\|CDD\|367887
NZ_CP022527.1\|WP_009426917.1\|1856922_1858905_-\|transketolase	unknown	unknown	gnl\|CDD\|183723
NZ_CP022527.1\|WP_009426911.1\|1850742_1851564_-\|CoA-ester-lyase	unknown	unknown	gnl\|CDD\|225184
NZ_CP022527.1\|WP_009426921.1\|1860516_1860804_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_036496525.1\|1842277_1842832_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|179895
NZ_CP022527.1\|WP_009426908.1\|1845956_1846397_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225696
NZ_CP022527.1\|WP_036496498.1\|1853272_1853905_+\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223698
NZ_CP022527.1\|WP_157058145.1\|1861504_1861681_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022527.1\|WP_009426918.1\|1859044_1859491_-\|cytochrome-c	unknown	unknown	gnl\|CDD\|226424
NZ_CP022527.1\|WP_094031133.1\|1860868_1861525_-\|MarC-family-protein	unknown	unknown	gnl\|CDD\|225006
NZ_CP022527.1\|WP_009426904.1\|1842913_1843714_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|236361
NZ_CP022527.1\|WP_009426919.1\|1859577_1860327_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187604
NZ_CP022527.1\|WP_036496494.1\|1851749_1852136_+\|RidA-family-protein	unknown	unknown	gnl\|CDD\|129116
NZ_CP022527.1\|WP_036496491.1\|1845037_1845970_+\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|237968
NZ_CP022527.1\|WP_036496489.1\|1844015_1845023_+\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896

Protein	Function_ID	Function_description	E-value
NZ_CP022527.1\|WP_009426924.1\|1861690_1862326_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|225496	COG2945, COG2945, Predicted hydrolase of the alpha/beta superfamily [General function prediction only].	5.37344e-75
NZ_CP022527.1\|WP_009426913.1\|1852185_1852944_-\|TatD-family-hydrolase	gnl\|CDD\|223162	COG0084, TatD, Mg-dependent DNase [DNA replication, recombination, and repair].	6.37249e-72
NZ_CP022527.1\|WP_009426916.1\|1855144_1856836_-\|D-lactate-dehydrogenase	gnl\|CDD\|236872	PRK11183, PRK11183, D-lactate dehydrogenase; Provisional.	0
NZ_CP022527.1\|WP_009426910.1\|1849199_1850390_-\|hypothetical-protein	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	1.61057e-06
NZ_CP022527.1\|WP_094031132.1\|1846553_1849076_-\|S9-family-peptidase	gnl\|CDD\|224422	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism].	9.31936e-85
NZ_CP022527.1\|WP_009426915.1\|1854107_1855010_-\|Dyp-type-peroxidase	gnl\|CDD\|367887	pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.	3.54394e-92
NZ_CP022527.1\|WP_009426917.1\|1856922_1858905_-\|transketolase	gnl\|CDD\|183723	PRK12753, PRK12753, transketolase; Reviewed.	0
NZ_CP022527.1\|WP_009426911.1\|1850742_1851564_-\|CoA-ester-lyase	gnl\|CDD\|225184	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism].	2.51344e-59
NZ_CP022527.1\|WP_036496525.1\|1842277_1842832_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|179895	PRK04930, PRK04930, glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional.	4.99407e-41
NZ_CP022527.1\|WP_009426908.1\|1845956_1846397_+\|hypothetical-protein	gnl\|CDD\|225696	COG3154, COG3154, Putative lipid carrier protein [Lipid metabolism].	1.05406e-19
NZ_CP022527.1\|WP_036496498.1\|1853272_1853905_+\|glutathione-S-transferase-family-protein	gnl\|CDD\|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	1.4907e-27
NZ_CP022527.1\|WP_009426918.1\|1859044_1859491_-\|cytochrome-c	gnl\|CDD\|226424	COG3909, COG3909, Cytochrome c556 [Energy production and conversion].	3.23539e-29
NZ_CP022527.1\|WP_094031133.1\|1860868_1861525_-\|MarC-family-protein	gnl\|CDD\|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	1.4668e-48
NZ_CP022527.1\|WP_009426904.1\|1842913_1843714_-\|NUDIX-domain-containing-protein	gnl\|CDD\|236361	PRK08999, PRK08999, Nudix family hydrolase.	3.74121e-49
NZ_CP022527.1\|WP_009426919.1\|1859577_1860327_+\|SDR-family-oxidoreductase	gnl\|CDD\|187604	cd05346, SDR_c5, classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.65822e-136
NZ_CP022527.1\|WP_036496494.1\|1851749_1852136_+\|RidA-family-protein	gnl\|CDD\|129116	TIGR00004, RutC_family_protein, reactive intermediate/imine deaminase. This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other].	5.16131e-62
NZ_CP022527.1\|WP_036496491.1\|1845037_1845970_+\|U32-family-peptidase	gnl\|CDD\|237968	PRK15447, PRK15447, putative protease; Provisional.	2.39427e-160
NZ_CP022527.1\|WP_036496489.1\|1844015_1845023_+\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.17686e-104

>NZ_CP022527.1|WP_009426913.1|1852185_1852944_-|TatD-family-hydrolase
MFTDTHAHLADSRLAARLPAVLAQAAAAGVTRFFVPATGRGDWQSVLALAAPAIVPAIGIHPWFADSHGAADISQLDALLSRHAHALVGEAGLDYRHAADDAARQTQRAILSAQLDLAAQHGRAVLLHNVRAGADLLCLLQKHGIRRGAVHAFSGSLEEAHAFIRQGLKIGIGSLLLNPSAKKARRAAAELPLSSLVLETDSPFMLKDAANTPANIRTIAQTVCTLRGIGLTELAEAAENNASQLLENPKAV
>NZ_CP022527.1|WP_036496494.1|1851749_1852136_+|RidA-family-protein
MAKQIIHTDQAPAAIGAYSQAVRAGDTVYLSGQIPLDPATMTVTGGGDFRAEAHQVFKNLRAVAEAAGGSLDQIVKLNAYLTDLDNFAVFNEVMAEYFAQPFPARAAVGVAALPKGVQVEAEAVLVLA
>NZ_CP022527.1|WP_009426911.1|1850742_1851564_-|CoA-ester-lyase
MLDQPLPKIFLFVPGNKPERIPKAFGIGADEVVVDWEDAVAENEKADAVRHMEAYCADPAARPVWLRINAPSSPRFAADLAALSQLDAVKGVVLPKTERPADITAVHHECGKPVIAAIETAKGMLNLPQLAFAQGLHALSYGCLDLCGELGLTHGTPAADTFFNHLRIELLLHSRLNGLHPPIETVFPDLADNDGLRTFTRFWRDMGFGGMLCVHPRQVAVTKLMMLPAPEETAFAEKVLAEAERNPSAVFQVDGRMVDAPVIARAKKLLGRM
>NZ_CP022527.1|WP_009426910.1|1849199_1850390_-|hypothetical-protein
MKHTKLYACLIAAAAVTTPLSAHAAYNVYSKDGLTLDIGGNVTAQFSKRHNRFTYTHDSSRYYYNYDLRQWENAQTNHDIETSDRRSRLGFERGSSWLQFRGQQRINQDWRATGTVQLGYYKDDLNLTAANVALDLRNVGSISFGKQFLHSGYVTRTGTYYPLEYFGNSSIRADYTGVPELQVSAYHLFPSQDDVRKTDNVNEIQGNGISATYRLRIAPDHSIRFGAGYTQSKRNSADNVKWASKKKHAAAGSIEYKYRDFTIAGDIGYEKEKIDIATLGQARSRYYGLKAEYAFTPRFKMAAGYGVKNTKKTAGSLGAFNTNAAWNQPDFIAANEEYVFPKIKRRKAYLKADYDLRENVTLYGRADVETVKNYVDDGEFSKRRRNEFTGGISLTF
>NZ_CP022527.1|WP_094031132.1|1846553_1849076_-|S9-family-peptidase
MKKTKLSLLLALALTAPQIVQTASAADTREHPANLYAAEYGYPETRTSQDETDRFETGEYGDPGLRTNSRNETVDPEIRKLKRDDGIDRYYGDTHVDKYRWLEDVDRIEPEHRYETSEDRKRNLFGTNWEDPELDKRRTGMETVRNEQGEVDKWVNAQNEATHNYLNKIPYIQEIGKRIDKLMDYEYLYFDYDREYGKLHYARYPDGYFRLSKKGADGKSQVILDEKELSKDGYTQIANYALNSNGKYFAYATRDGASDTDHKELYVLDTETLKTRHITTNIHVVDAGGTYGYPLEWKDNNNLYYVRSHGGWTDLMLHRMDKNEFNDPIIMKASDYDMTPDSFWIEDDRYLMVQGSLGSISNTLLLKDLKTGRWIQIHNRKMYDKINKADAFTNYTAAKFVRLDGNYIYVISEDNSEFGELLKIDIRSPQRKREVVIPARENHRLTAGVYQSGHYLMQYYSAGYDSLALFDENGKFVRDITPVAGGNISSLTAYDSGDKDAEDNRPKGTLAANEKDYKRYVWFYYQNKVTPATTYRYNVEEDKFFGVKRRDTIPFDADKYEMRTVSYPSKDGTMVPIVISHKKGLKLDGKNPTILYGYGGFNVDAYQGNFTTAAAAWMQNGGVYATAGLRGGKEYGSKWHDAGKQLNKQNVFDDFIAAGEFLIKEGYTSKDYLSISGGSNGGLLVGATMVQRPDLFRVAIPEVGVLDMLRHDKMYRTDYWINEYGMAEDSKAMYQKLLSYSPYHNVRDGVCYPSTMVMTSKRDDRVVPSHSYKFAAILQEKQSCMRPVFLNAAERHGHGDNTRAETKREMKEKFAFILHEMGVKSLPPVPDKEPQAQEKK
>NZ_CP022527.1|WP_009426908.1|1845956_1846397_+|hypothetical-protein
MPLPDITLPAWAGKIGGVLPAAPPRFALVATLNIMLKKGLLPADMSLFDGRKFEIDVLDAGVKVRFSANGEKFTAGGFDGTPDLRLAANGIDFMRMMLREEDPDTLFFNRKLQIEGDTELGLITKNLLDSVEWPFGEWFLQRGTGT
>NZ_CP022527.1|WP_036496491.1|1845037_1845970_+|U32-family-peptidase
MNPMKLSLGPILFFWQKEALLEFYAGLLDAPIDTVYLGEVVCSRRQKMRFADWYGLAEDLADSGKEVILSSQVLLESESDLKRLRKITGQDKFKVEANDMGAVKLAREHGIPIVAGASLNIYNESTLRLFKSLGAFRWIPQPELNRDKVAAVAAAAVSDGLETELFAWGKMPLAYSSRCFTARHYNLNKDSCEFRCLDYEHGMTMNTREGQPFLTINGIQTMSYGCQNLLPHHRDLQKIGIDILRLSPQMHGMADIIRLHRDVLDGQTDLADAMKELDALSTGTLVDGYWRGQAGIAAVQSIREENHAVA
>NZ_CP022527.1|WP_036496489.1|1844015_1845023_+|U32-family-peptidase
MRKIPELVCPAGNLPAMKTAVDNGADAVYMGLKDATNARNFPGLNFDMKSAREGVEYAHARGRQVLMAINTFAQAGQVERWQAAVDTAVLLGADAVIVADPAVMAYAANRYPDLRLHMSVQGSATNYEAINLMKDLFNVRRVVLPRVLTIDQVKHVIDHTDVEIEVFGFGSLCVMVEGRCILSSYATGESPNMQGVCSPAKAVRWEQLPDRMDVRLNRILIDRYNPNEPAGYPTLCKGRFEVNDETYYALEEPTSLNILEMLPEIIKIGVAAVKIEGRQRSPMYTAQVTKSLRQALDAAAADPARFRINPAWDSALSKVSEGHQTTLGAYSRPWK
>NZ_CP022527.1|WP_009426904.1|1842913_1843714_-|NUDIX-domain-containing-protein
MSATDTRPLLEVAAGIVFNENGEFLLSSRPAGKPYAGYWEFAGGKVEAGESAADALKREFAEELGIDIRRALPWLVKIHSYEHARVRLHFFRVPADGWAGGIQAKEGQSWAWQKAGDFTVSPMLPANGALLKALSVPTALTGRLKDGFYGANAAGAYRAVPPTRAAAEDKNLLLTAAEYLSDGRPSAAESLWLAVDNAADFARLLDVADVIVWHVGTHADAQTLLDTLHAGTPVPLVVSTDADTAAQYGADWLAAGAQAVAAEEQP
>NZ_CP022527.1|WP_036496525.1|1842277_1842832_+|NAD(P)H-dependent-oxidoreductase
MALVILAHPDFQKSVANKAVIEHLKAARPGDEIRDIAALYPDYRIDAAAEQQALTRHQTVVFQYPMYWYNMPAILKQYFDSVFTYGFAYGTGGDKLKGRHFVPSITIGSPEEDYRADGIAHFRVGELCKNIEQTAYYAQMNYIDPFYFHGTSPALYTPEQVAAKAQSCAGDLVSLLSELDKKAV
>NZ_CP022527.1|WP_036496498.1|1853272_1853905_+|glutathione-S-transferase-family-protein
MPNPELTLYTTPFSRGTYAVWMLKECAAPCTIVPLSSAKLHEADYLAVNPLGKVPALKAGGTILTETIAIITYLAEQFPEKNLIPAAGSIERGEYYRWLCFSIQLEYACMDKFFDRPSDHPRFHTGIGYGSFEEAFGVLRKHLSEHDYIVGGRFSALDLYYAALLLHFSRNMQVLDADPVFAAYIERHTARPAFAETMAWAQQTAAQLGE
>NZ_CP022527.1|WP_009426915.1|1854107_1855010_-|Dyp-type-peroxidase
MGTPQTAIIPDTITAAIYIEADVLDKEQTKAACRQALAALDDCRSRFPDHKLGMTIAFGADFWHSLGHENEGREIRPFMPLGNGLCPATQCDLMIHIQSEHTGLNYLLAEQVAAAFGNSIRIENETHGFRMPEERGLDGFVDGTENPHGEEKIAAIGTIAQDQPDAGGSYIVLQKYLHDLKKWSGISVAEQEQAVGRSKADNIEFARADRLPDSHLGRTNIKENGAGLKIVRRSLPFGYISGEHGLQFIAYCATLHNIDEQLKFMFGDKDGKIDLLLKHMSAAVRSAYYYAPSIERLADL
>NZ_CP022527.1|WP_009426916.1|1855144_1856836_-|D-lactate-dehydrogenase
MNATQLIENLTRIVGQKHIITDPAKTEQYRQGYRFGEGQALAVVRPGTLLEMWQILQECVAADVIVITQAANTGLTGGSTPSGHDYDRDIVIVNTMRIDIIQPINGNEQVVCLPGATLNRLEMLLKPLGREPHSVIGSSCIGASVLGGVCNNSGGALVQRGPAYTEMALFAEIDSEGRLNLVNHLGIDLGSTPEEILNNLQGWHYQQKDIDPNAGKGHDHAYCDHVRQVDAPTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQENHTAVFYIGTNDINELTDIRRAALSEFQSLPVSGEYIHRDAFDIAAVYGKDTFYAIKKFGTHQLPKLFDLKARADRIGKKIPFLPKHFTDKAMQFASRFMPQHLPQSLRDYRDRYEHHLILKMGGAGVEEARAFLKNYFANHSGAYFECNAEETQAAMLHRFAAASAAVRYRAVHDKEVEDIVALDIALRRDDRDWFETLPDEINSKISHKLYYGHFMCHVFHQDYIVKKGHDCMALEHEMLHLLDKRGAQYPAEHNVGHLYEAKPELKAFYRKLDPTNSFNPGIGHTSKKKNWAE
>NZ_CP022527.1|WP_009426917.1|1856922_1858905_-|transketolase
MTSPLANAIRFLSADAVQKANSGHPGAPMGMAEMAEVLWTQFLNHNPANPKFYNRDRFILSNGHASMLLYSLLHLTGYNLGIDDLKNFRQLHSKTPGHPEYGYTDGVETTTGPLGQGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCMMEGVSHEACSLAGTLGLGKLIVLYDDNNISIDGKVDGWFTENIPARFESYGWHVVPNVNGHDTAAIQTAIEAARAESGKPSLICCKTLIGKGSANKEGSHKTHGAPLGADEIEATRRHLGWNYGAFEIPQEIYDAWSAKEKGAKLEAAWNELFAQYQAKFPAEAAEFVRRMERKLPDNFDAYVQTALQEVCAKGETIATRKASQNSIEILAKELPELVGGSADLTPSNLTDWSNSVSVTRNGGGNYIHYGVREFGMGAIMNGLSLHGGVRPFGATFLMFSEYQRNALRMAALMRINPIFVFTHDSIGLGEDGPTHQPIEQTATLRLIPNMDVWRPCDTAESLVAWAEAAKAADRPSTLVFSRQNLKFLPRSSEQLENIKRGGYVVSEAAGEAKAVIIATGSEVELALNAQATLAAEGIAVRVVSMPSTNVFDRQDAAYRAAVLPDNLPKVAVEAGVSDGWYKYVGTNGAVLGLDRFGESAPADELFKLFGFTTENLVATVKSVL
>NZ_CP022527.1|WP_009426918.1|1859044_1859491_-|cytochrome-c
MNPLKAAALLLLLAACGGQPAGEPKGPASQERSAAFKRMMPEFSAMGKMVKGDETYNAAKFQAYAAAFADAAQKPFEHFQNDPQGNGDALPAVWQQPEAFKREQDAFLAAVAELNAKAQGGSLDDIKAAYSAAGASCKSCHDSYRRPK
>NZ_CP022527.1|WP_009426919.1|1859577_1860327_+|SDR-family-oxidoreductase
MAVLITGASAGFGEAMCAAFVRAGYKVIGAARRLPRLQAIRESLGADFYPLQMDLADRSSIAAALAQLPPEFAEIDCLINNGGLALGLDAAHEADFADWETMVETNILGLAYLTRQVLPQMVARRGGYIINIGSIAGTYPYPGGNVYGATKAFVRQFSLNLRADLQGTGVRVSNIEPGLCGGTEFSNVRFKGDNVRAEQVYAGTQYVNAQDIADTALWLYTRPPHMNVNAIEIMPTAQAFGALPVWREG
>NZ_CP022527.1|WP_009426921.1|1860516_1860804_+|hypothetical-protein
MSKELLGLFFLPAGVFAMCAAGLWQMYVVMNESYTLNRFQDRRLVWVVAAMFFSFSLAVYVFCPNARKKGIVFFLLGGIGLAMYVLARLWLPWKA
>NZ_CP022527.1|WP_094031133.1|1860868_1861525_-|MarC-family-protein
MFENYLHQFGLSFMAFFAIMNPVSSLPVYLSLTDGDDRRTARAVARKGLLIAFTIVAVFAFAGRFIFEMFGITLPALRIAGGILVFLIGFHMVQGNRSPMHRQPGQADAAPSSGMCYEEKMNVAISPLGTPLLAGPGTIATSMNLSAGDSLSGTVVVVAAFSLLCLITYTLFVFAPKITRLLGKNVMNVVTRMMGLILAVIGTQMLIAGLKGAFPLLN
>NZ_CP022527.1|WP_157058145.1|1861504_1861681_+|hypothetical-protein
MQIVFKHGRRVCVKKTADYTVYPPQRARGKTAAGRLKAAAAPDGQTRAAARTIPRPER
>NZ_CP022527.1|WP_009426924.1|1861690_1862326_+|alpha/beta-fold-hydrolase
MTPPETIAIPGPAGVLETIYLPAQGAEQGVAVINHPNPLQGGTNTNKVIQTAAKALAKLGFHCYLPNLRGVGGSGGGHDYGRGETDDCCAVVSFARSRHPQAAKLAIAGFSFGGYVALFAAQKCPPDLLLLMGPAVRHYEREREPDAPHPERTLLIHGETDEVVALQQSLDWAAPQDIPVVVLPQAGHFFHGKLIQLRDAVLRFAPAVLSR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1279209-1279242	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1333725-1333758	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1204163-1204196	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1263866-1263899	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1203260-1203293	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1236189-1236222	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1236180-1236213	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1204155-1204188	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1203511-1203544	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1204146-1204179	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1279330-1279363	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1279313-1279346	7	0.794
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1279305-1279338	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1279209-1279242	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1333725-1333758	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1204163-1204196	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1263866-1263899	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1203260-1203293	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1236189-1236222	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1236180-1236213	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1204155-1204188	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1203511-1203544	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1204146-1204179	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1279330-1279363	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1279313-1279346	7	0.794
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1279305-1279338	7	0.794
NZ_CP022527_1	1.17\|176521\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176521-176554	34	NZ_CP009123	Sphingopyxis fribergensis strain Kp5.2 plasmid pSfKp5.2, complete sequence	91537-91570	8	0.765
NZ_CP022527_1	1.41\|176522\|34\|NZ_CP022527\|PILER-CR	176522-176555	34	NZ_CP009123	Sphingopyxis fribergensis strain Kp5.2 plasmid pSfKp5.2, complete sequence	91537-91570	8	0.765
NZ_CP022527_1	1.6\|175793\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	175793-175826	34	NZ_CP023976	Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence	186966-186999	9	0.735
NZ_CP022527_1	1.17\|176521\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176521-176554	34	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	390915-390948	9	0.735
NZ_CP022527_1	1.30\|175794\|34\|NZ_CP022527\|PILER-CR	175794-175827	34	NZ_CP023976	Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence	186966-186999	9	0.735
NZ_CP022527_1	1.41\|176522\|34\|NZ_CP022527\|PILER-CR	176522-176555	34	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	390915-390948	9	0.735
NZ_CP022527_1	1.12\|176192\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176192-176225	34	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	149181-149214	10	0.706
NZ_CP022527_1	1.19\|176653\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176653-176686	34	MN543579	Klebsiella pneumoniae strain PM48 plasmid pPM48_140, complete sequence	53501-53534	10	0.706
NZ_CP022527_1	1.19\|176653\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176653-176686	34	MN543581	Klebsiella pneumoniae strain PM48TC plasmid pPM48TC_fusion, complete sequence	53501-53534	10	0.706
NZ_CP022527_1	1.19\|176653\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176653-176686	34	LR134207	Klebsiella aerogenes strain NCTC9667 genome assembly, plasmid: 2	163645-163678	10	0.706
NZ_CP022527_1	1.19\|176653\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176653-176686	34	NZ_CP034681	Klebsiella quasipneumoniae strain D120-1 plasmid pD120-1_296kb, complete sequence	196611-196644	10	0.706
NZ_CP022527_1	1.36\|176193\|34\|NZ_CP022527\|PILER-CR	176193-176226	34	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	149181-149214	10	0.706
NZ_CP022527_1	1.43\|176654\|34\|NZ_CP022527\|PILER-CR	176654-176687	34	MN543579	Klebsiella pneumoniae strain PM48 plasmid pPM48_140, complete sequence	53501-53534	10	0.706
NZ_CP022527_1	1.43\|176654\|34\|NZ_CP022527\|PILER-CR	176654-176687	34	MN543581	Klebsiella pneumoniae strain PM48TC plasmid pPM48TC_fusion, complete sequence	53501-53534	10	0.706
NZ_CP022527_1	1.43\|176654\|34\|NZ_CP022527\|PILER-CR	176654-176687	34	LR134207	Klebsiella aerogenes strain NCTC9667 genome assembly, plasmid: 2	163645-163678	10	0.706
NZ_CP022527_1	1.43\|176654\|34\|NZ_CP022527\|PILER-CR	176654-176687	34	NZ_CP034681	Klebsiella quasipneumoniae strain D120-1 plasmid pD120-1_296kb, complete sequence	196611-196644	10	0.706
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1956394-1956427	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	2053018-2053051	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1852443-1852476	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	2002948-2002981	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1851463-1851496	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1954296-1954329	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1954298-1954331	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1851787-1851820	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1851837-1851870	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1852423-1852456	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1956585-1956618	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1956583-1956616	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1956547-1956580	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1956394-1956427	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	2053018-2053051	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1852443-1852476	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	2002948-2002981	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1851463-1851496	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1954296-1954329	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1954298-1954331	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1851787-1851820	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1851837-1851870	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1852423-1852456	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1956585-1956618	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1956583-1956616	11	0.676
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1956547-1956580	11	0.676
NZ_CP022527_1	1.24\|176984\|34\|NZ_CP022527\|CRT,CRISPRCasFinder	176984-177017	34	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	599960-599993	12	0.647
NZ_CP022527_1	1.48\|176985\|34\|NZ_CP022527\|PILER-CR	176985-177018	34	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	599960-599993	12	0.647

1. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

2. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

3. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

4. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

5. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

6. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

7. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

8. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

9. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

10. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

11. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

12. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

13. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

14. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

15. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

16. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

17. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

18. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

19. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

20. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

21. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

22. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

23. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

24. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

25. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

26. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggcatccgaacgcgcgcggcaggccgtaccgggg	Protospacer
 *. .********* ****************  *

27. spacer 1.17|176521|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP009123 (Sphingopyxis fribergensis strain Kp5.2 plasmid pSfKp5.2, complete sequence) position: , mismatch: 8, identity: 0.765

gcatggcggatgccgacgtgttcaacacctgcct	CRISPR spacer
gcatggccgatgccgacgcgttcatgaacggcgc	Protospacer
******* **********.*****  * * ** .

28. spacer 1.41|176522|34|NZ_CP022527|PILER-CR matches to NZ_CP009123 (Sphingopyxis fribergensis strain Kp5.2 plasmid pSfKp5.2, complete sequence) position: , mismatch: 8, identity: 0.765

gcatggcggatgccgacgtgttcaacacctgcct	CRISPR spacer
gcatggccgatgccgacgcgttcatgaacggcgc	Protospacer
******* **********.*****  * * ** .

29. spacer 1.6|175793|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP023976 (Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence) position: , mismatch: 9, identity: 0.735

aaccgtctgccgcagcacgcaagcccgttgcggt	CRISPR spacer
gaccatctgccgcagcacgcaggccagcggcctc	Protospacer
.***.****************.*** *. **  .

30. spacer 1.17|176521|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 9, identity: 0.735

gcatggcggatgccgacgtgttcaacacctgcct	CRISPR spacer
accggccggatgccgacgtgatctacaccttcgc	Protospacer
.*  * ************** ** ****** * .

31. spacer 1.30|175794|34|NZ_CP022527|PILER-CR matches to NZ_CP023976 (Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence) position: , mismatch: 9, identity: 0.735

aaccgtctgccgcagcacgcaagcccgttgcggt	CRISPR spacer
gaccatctgccgcagcacgcaggccagcggcctc	Protospacer
.***.****************.*** *. **  .

32. spacer 1.41|176522|34|NZ_CP022527|PILER-CR matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 9, identity: 0.735

gcatggcggatgccgacgtgttcaacacctgcct	CRISPR spacer
accggccggatgccgacgtgatctacaccttcgc	Protospacer
.*  * ************** ** ****** * .

33. spacer 1.12|176192|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 10, identity: 0.706

gacggtggacggacacgccgccggcgaaggggac	CRISPR spacer
agtcgcggccggatacgccgccggcgaaggtctc	Protospacer
... *.** ****.****************   *

34. spacer 1.19|176653|34|NZ_CP022527|CRT,CRISPRCasFinder matches to MN543579 (Klebsiella pneumoniae strain PM48 plasmid pPM48_140, complete sequence) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

35. spacer 1.19|176653|34|NZ_CP022527|CRT,CRISPRCasFinder matches to MN543581 (Klebsiella pneumoniae strain PM48TC plasmid pPM48TC_fusion, complete sequence) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

36. spacer 1.19|176653|34|NZ_CP022527|CRT,CRISPRCasFinder matches to LR134207 (Klebsiella aerogenes strain NCTC9667 genome assembly, plasmid: 2) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

37. spacer 1.19|176653|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP034681 (Klebsiella quasipneumoniae strain D120-1 plasmid pD120-1_296kb, complete sequence) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

38. spacer 1.36|176193|34|NZ_CP022527|PILER-CR matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 10, identity: 0.706

gacggtggacggacacgccgccggcgaaggggac	CRISPR spacer
agtcgcggccggatacgccgccggcgaaggtctc	Protospacer
... *.** ****.****************   *

39. spacer 1.43|176654|34|NZ_CP022527|PILER-CR matches to MN543579 (Klebsiella pneumoniae strain PM48 plasmid pPM48_140, complete sequence) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

40. spacer 1.43|176654|34|NZ_CP022527|PILER-CR matches to MN543581 (Klebsiella pneumoniae strain PM48TC plasmid pPM48TC_fusion, complete sequence) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

41. spacer 1.43|176654|34|NZ_CP022527|PILER-CR matches to LR134207 (Klebsiella aerogenes strain NCTC9667 genome assembly, plasmid: 2) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

42. spacer 1.43|176654|34|NZ_CP022527|PILER-CR matches to NZ_CP034681 (Klebsiella quasipneumoniae strain D120-1 plasmid pD120-1_296kb, complete sequence) position: , mismatch: 10, identity: 0.706

caggtttcggtttatcgcacccccgatgaaaata	CRISPR spacer
agtgccgcggtttatcgctcccctgatgaaacca	Protospacer
 . *.. *********** ****.******* .*

43. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

44. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

45. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

46. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

47. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

48. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

49. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

50. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

51. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

52. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

53. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

54. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

55. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

56. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

57. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

58. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

59. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

60. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

61. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

62. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

63. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

64. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

65. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

66. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

67. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

68. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
ggtcccggaacgcgagcggctggccgcggaaggc	Protospacer
 ***** ************* *****..  .

69. spacer 1.24|176984|34|NZ_CP022527|CRT,CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 12, identity: 0.647

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
tcagcccgaacgccatcggcaggccgtagaagaa	Protospacer
.   ********* * ************  .  .

70. spacer 1.48|176985|34|NZ_CP022527|PILER-CR matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 12, identity: 0.647

cgtccccgaacgcgagcggcaggccgtaccgtcg	CRISPR spacer
tcagcccgaacgccatcggcaggccgtagaagaa	Protospacer
.   ********* * ************  .  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

508216 : 576361

Burkholderia_virus(30.95%)

tRNA,tail,plate,transposase,integrase

attL 543272:543289|attR 576362:576379

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009426260.1\|508216_508660_-	phage virion morphogenesis protein	A0A076FSU1	Pseudomonas_phage	1.5e-22	45.8
WP_009426261.1\|508662_509565_-	hypothetical protein	A0A0M4UTA3	Ralstonia_phage	9.3e-64	46.4
WP_009426262.1\|509561_511031_-	DUF935 family protein	A4JWJ5	Burkholderia_virus	2.0e-108	46.1
WP_094030878.1\|511052_512546_-	hypothetical protein	Q6QIC1	Burkholderia_phage	3.5e-201	68.8
WP_009426265.1\|512542_513088_-	DUF3486 family protein	Q6QIC2	Burkholderia_phage	1.3e-31	41.7
WP_029609188.1\|513089_513392_-	hypothetical protein	A0A2H4JGU5	uncultured_Caudovirales_phage	1.8e-27	63.9
WP_013448349.1\|513403_513724_-	hypothetical protein	A4JWP6	Burkholderia_virus	1.0e-12	43.9
WP_009426268.1\|513726_513936_-	TraR/DksA family transcriptional regulator	V5USD3	Shigella_phage	3.5e-06	41.5
WP_009426269.1\|513928_514150_-	hypothetical protein	NA	NA	NA	NA
WP_009426270.1\|514127_514517_-	hypothetical protein	NA	NA	NA	NA
WP_009426271.1\|514509_514848_-	hypothetical protein	NA	NA	NA	NA
WP_009426272.1\|514956_515460_-	glycoside hydrolase family 108 protein	A0A0M3LSH2	Mannheimia_phage	1.2e-52	60.7
WP_157058132.1\|515542_515977_-	hypothetical protein	NA	NA	NA	NA
WP_062546260.1\|515973_516216_-	hypothetical protein	NA	NA	NA	NA
WP_036496167.1\|516233_517154_-	hypothetical protein	NA	NA	NA	NA
WP_009426276.1\|517330_517891_-	hypothetical protein	NA	NA	NA	NA
WP_009426277.1\|517914_518580_-	helix-turn-helix transcriptional regulator	A0A2I7S9A5	Vibrio_phage	9.7e-34	41.0
WP_009426278.1\|518722_518911_+	DNA-binding protein	NA	NA	NA	NA
WP_009426279.1\|518919_519204_+	hypothetical protein	NA	NA	NA	NA
WP_009426280.1\|519240_520116_+	hypothetical protein	A4JWN3	Burkholderia_virus	4.4e-50	41.9
WP_094030879.1\|520096_521875_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q6QIE0	Burkholderia_phage	2.1e-139	45.5
WP_009426282.1\|521916_523062_+	AAA family ATPase	A4JWN1	Burkholderia_virus	1.0e-99	49.0
WP_094030880.1\|523063_523324_+	hypothetical protein	NA	NA	NA	NA
WP_009426285.1\|523320_523515_+	hypothetical protein	NA	NA	NA	NA
WP_009426286.1\|523511_524012_+	hypothetical protein	A0A2H4JFV8	uncultured_Caudovirales_phage	5.0e-27	40.0
WP_009426287.1\|523995_524448_+	hypothetical protein	NA	NA	NA	NA
WP_009426288.1\|524449_524635_+	hypothetical protein	NA	NA	NA	NA
WP_009426289.1\|524631_525255_+	DUF3164 family protein	A0A0M3LQ92	Mannheimia_phage	8.4e-56	52.7
WP_009426290.1\|525257_525455_+	hypothetical protein	NA	NA	NA	NA
WP_009426291.1\|525507_525783_+	HU family DNA-binding protein	A3E2K9	Sodalis_phage	6.2e-19	60.7
WP_009426292.1\|525951_526428_+	regulatory protein GemA	A4JWM5	Burkholderia_virus	1.4e-21	46.5
WP_036496171.1\|526420_526747_+	transcriptional regulator	Q6QIE8	Burkholderia_phage	1.8e-17	41.5
WP_094030881.1\|526960_528085_+	2-oxoacid:acceptor oxidoreductase	Q6QIB7	Burkholderia_phage	3.7e-70	47.7
WP_009426295.1\|528143_529082_+	hypothetical protein	A4JWK0	Burkholderia_virus	2.9e-52	42.4
WP_009426296.1\|529131_529401_+	hypothetical protein	A0A2D2W313	Escherichia_phage	5.7e-09	46.6
WP_009426297.1\|529401_529740_+	DUF2190 family protein	NA	NA	NA	NA
WP_009426298.1\|529742_530021_+	hypothetical protein	NA	NA	NA	NA
WP_009426299.1\|530024_530450_+	DUF1320 domain-containing protein	A0A0M3LP98	Mannheimia_phage	2.4e-09	31.6
WP_009426300.1\|530449_530947_+	hypothetical protein	Q6QIB2	Burkholderia_phage	4.0e-24	37.3
WP_094030882.1\|530958_532353_+\|tail	phage tail protein	A4JWK5	Burkholderia_virus	1.5e-100	45.4
WP_009426595.1\|532375_532891_+\|tail	phage major tail tube protein	A4JWK6	Burkholderia_virus	3.0e-43	50.3
WP_009426596.1\|532996_533290_+\|tail	phage tail assembly protein	Q6QIA8	Burkholderia_phage	4.9e-06	40.3
WP_009426597.1\|533324_533468_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_157058137.1\|533464_533770_-	trehalose-6-phosphate synthase	NA	NA	NA	NA
WP_009426599.1\|533818_536224_+\|tail	phage tail tape measure protein	A0A1B2LRQ0	Wolbachia_phage	3.8e-88	37.5
WP_094030883.1\|536223_537120_+\|tail	phage tail protein	A4JWL1	Burkholderia_virus	2.8e-20	35.4
WP_094030884.1\|537116_537338_+	hypothetical protein	Q6QIA3	Burkholderia_phage	2.3e-08	38.2
WP_094031206.1\|537325_538447_+	hypothetical protein	A4JWL3	Burkholderia_virus	3.7e-70	44.6
WP_094031207.1\|538415_539045_+\|plate	phage baseplate assembly protein V	A4JWL4	Burkholderia_virus	3.5e-25	40.0
WP_036496892.1\|539117_539495_+\|plate	phage baseplate protein	NA	NA	NA	NA
WP_009427644.1\|539485_540619_+\|plate	baseplate J/gp47 family protein	A4JWL6	Burkholderia_virus	1.9e-58	41.0
WP_094030885.1\|540622_541201_+\|tail	phage tail protein	Q6QI98	Burkholderia_phage	4.0e-44	48.7
WP_094030886.1\|541213_541777_+	hypothetical protein	A4JWL8	Burkholderia_virus	5.0e-07	31.0
WP_083479437.1\|542086_543238_+	DUF560 domain-containing protein	NA	NA	NA	NA
543272:543289	attL	NA	NA	NA	NA
WP_094030887.1\|543418_545032_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-15	28.4
WP_009425765.1\|545057_545966_-	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_094030888.1\|546064_546985_-	oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_009425767.1\|547159_548962_-	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	2.4e-164	49.1
WP_009425768.1\|549050_550670_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_009425770.1\|550986_551475_+	transcription elongation factor GreB	NA	NA	NA	NA
WP_009425772.1\|551716_553243_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_036495846.1\|553439_557048_+	bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA	NA	NA	NA	NA
WP_094030889.1\|557466_559059_+	peptide chain release factor 3	A0A2K9L6L3	Tupanvirus	7.0e-14	36.0
WP_036495877.1\|559185_560154_+	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	3.8e-47	46.8
WP_009425777.1\|560223_560685_+	macro domain protein	C9DG59	Deftia_phage	9.1e-23	41.8
WP_009425779.1\|560933_562148_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_009425780.1\|562284_564444_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.3e-183	51.6
WP_036495849.1\|564481_565102_+	DUF2238 domain-containing protein	NA	NA	NA	NA
WP_009425782.1\|565212_565599_-	META domain-containing protein	NA	NA	NA	NA
WP_009425783.1\|565660_565996_-	DUF4298 domain-containing protein	NA	NA	NA	NA
WP_009425784.1\|566161_567337_-	oxygen-independent coproporphyrinogen III oxidase-like protein	NA	NA	NA	NA
WP_009425785.1\|567333_567696_-	conjugal transfer protein TraF	NA	NA	NA	NA
WP_009425786.1\|567753_568347_-	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	NA	NA	NA	NA
WP_009425787.1\|568339_568600_-	hypothetical protein	NA	NA	NA	NA
WP_009425788.1\|568833_569301_-	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_094030890.1\|569297_570401_-	conjugal transfer protein	NA	NA	NA	NA
WP_009425790.1\|570520_570787_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_009425792.1\|570982_571900_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_009425793.1\|572069_572600_-	hypothetical protein	NA	NA	NA	NA
WP_009425794.1\|572601_572973_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_009425795.1\|573073_573943_+	lipid A biosynthesis lauroyl acyltransferase	A0A1W6JP29	Morganella_phage	2.0e-26	29.3
WP_009425796.1\|574049_574805_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_009425797.1\|574809_575154_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_094030891.1\|575371_576361_+\|integrase	site-specific integrase	Q19US1	Mannheimia_phage	1.6e-69	44.7
576362:576379	attR	NA	NA	NA	NA

DBSCAN-SWA_2

590004 : 646966

Burkholderia_phage(16.67%)

head,holin,tRNA,portal,terminase,tail,plate,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094030911.1\|590004_590457_-\|tail	phage tail protein	A4PE53	Ralstonia_virus	5.2e-23	42.4
WP_094030912.1\|590459_593255_-\|tail	phage tail tape measure protein	V5YUN9	Pseudomonas_phage	8.5e-47	32.1
WP_157697500.1\|593285_593432_+	hypothetical protein	NA	NA	NA	NA
WP_094030913.1\|593499_593685_-	hypothetical protein	NA	NA	NA	NA
WP_094030914.1\|593702_594056_-	hypothetical protein	NA	NA	NA	NA
WP_094030915.1\|594079_594586_-\|tail	phage major tail tube protein	Q19UP8	Mannheimia_phage	6.4e-30	40.5
WP_094030916.1\|594632_595829_-\|tail	phage tail protein	F1BUU3	Erwinia_phage	2.2e-97	47.6
WP_094030917.1\|595924_596206_-	hypothetical protein	NA	NA	NA	NA
WP_094030918.1\|596206_597835_-	hypothetical protein	NA	NA	NA	NA
WP_094030919.1\|597834_598413_-\|tail	phage tail protein I	U5N0U8	Enterobacteria_phage	2.1e-08	28.0
WP_094030920.1\|598412_599309_-\|plate	baseplate protein	R4JDM0	Burkholderia_phage	8.1e-52	46.2
WP_094030921.1\|599305_599629_-\|plate	phage baseplate protein	A0A1S5NNH3	Burkholderia_phage	1.7e-15	47.9
WP_094030922.1\|599625_600252_-\|plate	phage baseplate assembly protein V	A0A2I8TV69	Erwinia_phage	4.7e-22	36.0
WP_094030923.1\|600383_601016_-	hypothetical protein	R4JJX8	Burkholderia_phage	1.8e-05	25.6
WP_094030924.1\|601029_601461_-\|tail	phage tail protein	E5G6N3	Salmonella_phage	1.7e-15	37.1
WP_094030925.1\|601474_601699_-	TraR/DksA family transcriptional regulator	Q9ZXI6	Pseudomonas_virus	1.5e-10	52.2
WP_094030926.1\|601695_601947_-	hypothetical protein	NA	NA	NA	NA
WP_157697501.1\|601943_602264_-	hypothetical protein	NA	NA	NA	NA
WP_094030928.1\|602282_602765_-	M15 family metallopeptidase	A0A0S0N9W0	Pseudomonas_phage	1.2e-44	57.6
WP_157697503.1\|602801_603155_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_094030929.1\|603151_603505_-	hypothetical protein	NA	NA	NA	NA
WP_094030930.1\|603512_603731_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_157697505.1\|603727_604207_-\|head	head completion/stabilization protein	V9IQW6	Stenotrophomonas_phage	3.2e-15	33.3
WP_094031208.1\|604314_604977_-\|terminase	terminase	A0A0M4R523	Salmonella_phage	2.3e-19	32.0
WP_094030932.1\|605025_606048_-\|capsid	phage major capsid protein, P2 family	Q19UT3	Mannheimia_phage	6.9e-63	44.5
WP_157697507.1\|606088_606994_-	hypothetical protein	Q01088	Escherichia_phage	3.7e-28	53.4
WP_094030934.1\|607146_608940_+	oxidoreductase	E5FFI8	Burkholderia_phage	1.2e-158	50.2
WP_094031209.1\|608956_609937_+\|portal	phage portal protein	A4PE27	Ralstonia_virus	7.5e-83	49.2
WP_009425798.1\|610617_611274_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.1e-57	53.7
WP_157697508.1\|611356_611560_+	hypothetical protein	NA	NA	NA	NA
WP_009425800.1\|611668_613117_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_009425801.1\|613165_613636_-	iron-sulfur cluster repair di-iron protein	NA	NA	NA	NA
WP_094030935.1\|613918_614794_-	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	1.1e-24	27.6
WP_009425804.1\|614798_615245_-	peroxiredoxin	NA	NA	NA	NA
WP_009425805.1\|615582_618165_+	ATP-dependent chaperone ClpB	A0A223W0B1	Agrobacterium_phage	1.1e-117	35.3
WP_009425807.1\|618412_619408_-	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_009425809.1\|619638_621015_-	hypothetical protein	NA	NA	NA	NA
WP_036495879.1\|621231_623442_-	TonB-dependent receptor	NA	NA	NA	NA
WP_009425811.1\|623649_624336_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.5e-21	31.3
WP_009425812.1\|624328_625006_-	molybdate ABC transporter permease subunit	NA	NA	NA	NA
WP_009425813.1\|625241_628010_-	insulinase family protein	NA	NA	NA	NA
WP_094030936.1\|628224_630054_-	TonB-dependent receptor	NA	NA	NA	NA
WP_009425816.1\|630053_630764_-	TonB-dependent receptor plug domain-containing protein	NA	NA	NA	NA
WP_009425818.1\|631075_631813_-	toxin-antitoxin system YwqK family antitoxin	NA	NA	NA	NA
WP_094030937.1\|631816_633172_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_009425820.1\|633447_634008_-	hypothetical protein	NA	NA	NA	NA
WP_009425821.1\|634080_634635_-	hypothetical protein	NA	NA	NA	NA
WP_009425823.1\|634857_635685_+	sulfate ABC transporter permease subunit CysT	NA	NA	NA	NA
WP_009425824.1\|635681_636533_+	sulfate ABC transporter permease subunit CysW	NA	NA	NA	NA
WP_009425826.1\|636529_637600_+	sulfate/molybdate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-28	35.0
WP_009425827.1\|637956_638913_-	hypothetical protein	NA	NA	NA	NA
WP_094030938.1\|639079_640387_+	M23 family metallopeptidase	A8ATH6	Listeria_phage	3.0e-23	50.4
WP_094030939.1\|640412_640865_+	hypothetical protein	NA	NA	NA	NA
WP_009425830.1\|640861_642115_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_009425831.1\|642170_642419_-	BolA family transcriptional regulator	NA	NA	NA	NA
WP_009425833.1\|642603_643377_+	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_009425834.1\|643502_644114_+	hypothetical protein	NA	NA	NA	NA
WP_094030940.1\|644143_645961_-	potassium transporter	NA	NA	NA	NA
WP_036495862.1\|646132_646966_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022527

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection