CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Prophage number
NZ_CP022540	Antarctobacter heliothermus strain SMS3 chromosome, complete genome	2 crisprs	WYL,csa3,DEDDh,RT,DinG	2	3
NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	0 crisprs	NA	0	3
NZ_CP022543	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-3, complete sequence	0 crisprs	NA	0	1
NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022540_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022540_1

805982-806074

Orphan

Consensus_repeat	Method
CCCAGACCCGAACAAGTCGGACAGGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022540_1

>merge|NZ_CP022540|1|805982-806074|CRISPRCasFinder
CCCAGACCCGAACAAGTCGGACAGGTCCGCTCCACTGTAAAGAACCCCTGCGTGGCACGCACCTTACCCAGACCCGAACAAGTCGGACAGGTC

>NZ_CP022540|1|1|805982-806074|CRISPRCasFinder
CCCAGACCCGAACAAGTCGGACAGGTC	CGCTCCACTGTAAAGAACCCCTGCGTGGCACGCACCTTA
CCCAGACCCGAACAAGTCGGACAGGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022540.1\|WP_094033731.1\|803025_804585_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|270371
NZ_CP022540.1\|WP_094033725.1\|793471_795964_+\|translation-initiation-factor-IF-2	unknown	unknown	gnl\|CDD\|235401
NZ_CP022540.1\|WP_094033729.1\|798108_798969_-\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|234605
NZ_CP022540.1\|WP_094033736.1\|810078_810672_-\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|226176
NZ_CP022540.1\|WP_094033730.1\|799143_801858_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP022540.1\|WP_094033728.1\|796886_798104_-\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl\|CDD\|235441
NZ_CP022540.1\|WP_094036909.1\|804595_805357_-\|JAB-domain-containing-protein	unknown	unknown	gnl\|CDD\|178801
NZ_CP022540.1\|WP_094036911.1\|813847_814738_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP022540.1\|WP_094033738.1\|812483_813707_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133029
NZ_CP022540.1\|WP_094036910.1\|810720_811551_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224596
NZ_CP022540.1\|WP_094033724.1\|792829_793462_+\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|236401
NZ_CP022540.1\|WP_094033733.1\|806663_808586_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_CP022540.1\|WP_094033734.1\|808811_809414_+\|alpha-ketoglutarate-dependent-dioxygenase-AlkB	unknown	unknown	gnl\|CDD\|372627
NZ_CP022540.1\|WP_094033722.1\|790609_791188_+\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NZ_CP022540.1\|WP_094033740.1\|815707_816895_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340838
NZ_CP022540.1\|WP_094033737.1\|811677_812475_+\|3'(2'),5'-bisphosphate-nucleotidase-CysQ	unknown	unknown	gnl\|CDD\|238816
NZ_CP022540.1\|WP_094033727.1\|796425_796824_-\|8-oxo-dGTP-diphosphatase-MutT	unknown	unknown	gnl\|CDD\|239517
NZ_CP022540.1\|WP_094033723.1\|791193_792822_+\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|236410
NZ_CP022540.1\|WP_157733391.1\|809461_810073_-\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|377965
NZ_CP022540.1\|WP_094033739.1\|814743_815727_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|224012

Protein	Function_ID	Function_description	E-value
NZ_CP022540.1\|WP_094033731.1\|803025_804585_+\|OmpA-family-protein	gnl\|CDD\|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.94879e-46
NZ_CP022540.1\|WP_094033725.1\|793471_795964_+\|translation-initiation-factor-IF-2	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_CP022540.1\|WP_094033729.1\|798108_798969_-\|peptidylprolyl-isomerase	gnl\|CDD\|234605	PRK00059, prsA, peptidylprolyl isomerase; Provisional.	1.03981e-26
NZ_CP022540.1\|WP_094033736.1\|810078_810672_-\|SH3-domain-containing-protein	gnl\|CDD\|226176	COG3650, COG3650, Predicted membrane protein [Function unknown].	1.90573e-14
NZ_CP022540.1\|WP_094033730.1\|799143_801858_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP022540.1\|WP_094033728.1\|796886_798104_-\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl\|CDD\|235441	PRK05388, argJ, bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ.	0
NZ_CP022540.1\|WP_094036909.1\|804595_805357_-\|JAB-domain-containing-protein	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	9.2734e-106
NZ_CP022540.1\|WP_094036911.1\|813847_814738_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	9.91483e-149
NZ_CP022540.1\|WP_094033738.1\|812483_813707_+\|glycosyltransferase	gnl\|CDD\|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	3.05719e-27
NZ_CP022540.1\|WP_094036910.1\|810720_811551_-\|ABC-transporter-permease	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.22088e-11
NZ_CP022540.1\|WP_094033724.1\|792829_793462_+\|RNA-binding-protein	gnl\|CDD\|236401	PRK09190, PRK09190, RNA-binding protein.	1.99162e-87
NZ_CP022540.1\|WP_094033733.1\|806663_808586_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP022540.1\|WP_094033734.1\|808811_809414_+\|alpha-ketoglutarate-dependent-dioxygenase-AlkB	gnl\|CDD\|372627	pfam13532, 2OG-FeII_Oxy_2, 2OG-Fe(II) oxygenase superfamily.	6.12959e-65
NZ_CP022540.1\|WP_094033722.1\|790609_791188_+\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	2.13577e-54
NZ_CP022540.1\|WP_094033740.1\|815707_816895_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340838	cd03809, GT4_MtfB-like, glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.	4.07229e-51
NZ_CP022540.1\|WP_094033737.1\|811677_812475_+\|3'(2'),5'-bisphosphate-nucleotidase-CysQ	gnl\|CDD\|238816	cd01638, CysQ, CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in cysteine biosynthesis (a principal route of sulfur assimilation).	1.93267e-104
NZ_CP022540.1\|WP_094033727.1\|796425_796824_-\|8-oxo-dGTP-diphosphatase-MutT	gnl\|CDD\|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	3.99869e-57
NZ_CP022540.1\|WP_094033723.1\|791193_792822_+\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|236410	PRK09202, nusA, transcription elongation factor NusA; Validated.	0
NZ_CP022540.1\|WP_157733391.1\|809461_810073_-\|SH3-domain-containing-protein	gnl\|CDD\|377965	pfam08239, SH3_3, Bacterial SH3 domain.	7.92141e-05
NZ_CP022540.1\|WP_094033739.1\|814743_815727_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	7.93191e-173

>NZ_CP022540.1|WP_094036909.1|804595_805357_-|JAB-domain-containing-protein
MTRGPHFSDSQAALFDLDEAARPVTGTEKLPSYIRDHRARLRERFLIGGADALPDYEMLELVLFRAIPRRDVKPLARHLLETFGDFNGVLSAPPHRLREVKGLGDAVLTELKIVEAAAHRLARSRVLGKQVLSSWDVLLDYCQTSMAHRDTEQFRILFLDRKNVLIADEPQARGTVDHVPVYPREVVKRALELNASAIILVHNHPSGDPTPSQADIDMTAQIQMAADALGITLHDHLVIGKSQELSFRSEGLL
>NZ_CP022540.1|WP_094033731.1|803025_804585_+|OmpA-family-protein
MWIGRAAVFAALFFAVQAGVALAQDITLKSRDGTISLSGTLLGFDGEFYRVETRFGELTVDGSGVTCTGVGCPSLTGYVARVTISGSATLGRVLMPALIEGFALRNGLEARRTTTPDGDLVYALQEAGGGPTVGEFTFRINNTDKGFSDLAADDADIVMALREIRAEEVTAAKNAGLGDLTQANRSRVLALDAMVPIVSSHNPVDTLSIVQLAEILSGHIDNWKALGGPDAPITVHLRDDGSGMVQGLQDRLLRPARQSLIDGAARHDSNPALIRAVAHDPFGLGMASYSEVGNTKSLVLTGPCGFRLRAARRSIKTEDYPLTAPMFLYVPARRLPRLAREFLAYTHSPPAQIVIRRAAFVDQTPEEIAIDLQGDRLANAVTVAEGPEGLSTLQDMVRALAPMRRLTVTFRFEAGSARLDAQSRSNVLALARAMESGVYDGRRLVFVGFSDGVGPASANLDIADRRAVAVREAVLAAAETADLERIDIAVQAFGEALPMACDDSAWGRQVNRRVEVWVR
>NZ_CP022540.1|WP_094033730.1|799143_801858_+|preprotein-translocase-subunit-SecA
MLGKIARKVFGSPNDRKIKAVRPLVEKINALEPEFAALDDAGLIAKTQEFRERIEKGESLDNLLPEAFANCREGARRALGLRAFDVQLMGGIFLHQGNIAEMKTGEGKTLVATFPAYLNALTGKGVHIVTVNDYLAKRDAEWMSNVYGALGLTTGVIYPRQPDDEKQQAYACDITYATNNELGFDYLRDNMKSELNQIFQRDHFFAVVDEVDSILIDEARTPLIISGPSQDRSELYVAVDKLIPDLTDEHYTVDEKTRNVTFTDEGNEFLEEQLQGRGLLEEGQSLYDPESTTIVHHVNQAIRAHKLFTRDKDYIVRDSEVVLIDEFTGRMMSGRRLSDGLHQAIEAKEGCDIQPENVTLASVTFQNYFRLYDRLSGMTGTAATEAEEFGQIYGLGVVEVPTNVPISRIDDDDAVYRTGTEKYAAIVAEIHKSHEKGQPVLVGTTSIEKSEMLSAMLTQANLKHNVLNARQHEQEAQIIADAGKLGAVTIATNMAGRGTDIKLGGNVEFKVMEAITANPDRNPDEIRSEIEEQHKSDEQAVKDAGGLFVLATERHESRRIDNQLRGRSGRQGDPGRSSFFLSLEDDLMRIFGSERLEKVLSSLGMKEGEAIVHPWVNKSLERAQAKVEGRNFDIRKQLLKFDDVMNDQRKVIFSQRREIMESADVSEITTDMRHEVIDDLVDTYAPPKAYADQWDMPGLYAAVMEQLDLDLPIIGWAEEDGVDQDVLRERIAEASDKAMDEKTEAFGAKTMRQIEKQVLLQAIDAKWRDHLLTLEHLRSVVGFRGYAQRDPLNEYKNESFQLFENMLDSLRETVTVQLSRVRPMSEEEQQAMVEEMRRQQEEMQRSLQQAAATPAPAGETVAPEGQAAEGFDENDPETWGTPGRNDACPCGSGKKFKHCHGRLS
>NZ_CP022540.1|WP_094033729.1|798108_798969_-|peptidylprolyl-isomerase
MSKTLMKLSAAALALCVAFPVQAQDTPAEITVDTVVATVNGTDITFGHMLMARASLPERFQDAPSAELWEGLLERLIQYEALSQSDKAKETDRVALALDNEKRELMAAEAMQAIADGAVSEEAIAEAYKAGYTDAVQGVEYNASHILVETEEKAKELVAELEGGADFAELARANSTGPTGPNGGLLGWFGKGRMVAAFEEAVATMEPGELSAPVQTRFGWHVIKLNETRAVDAPPLEEVRAQLEQQIKQDAVQSYIKDLAESGEVTRLDYSEIDTSIINNLGLLAD
>NZ_CP022540.1|WP_094033728.1|796886_798104_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MPPRSPLAPAEFPALPVIGGARFAIAEAGVRYKGRPDVMLAMLDPGSVMAGVFTRSATRSANVLDCQAKIAADSSEGAAIVVNSGNSNAFTGRAGEGSVEAICEAVAEQTGLPASRVFTSSTGVIGERLPHDRITAKLEELTGKLDGASLPDAARAIMTTDTFPKAATAQIEVDGKPVKIAGIAKGSGMIAPDMATMLVYIFTDAKIGRAELQAMVSELNAKTFNNITVDSDTSTSDTLLMAATGASGVDVAWNAEFTQALYGVMLDLAHQVVRDGEGATKFVTVHVNHAASEADARTHALSIANSPLVKTALAGEDPNWGRIVMAVGKSGAAADRDALSISFGELLVAEKGWVAESYREADGAAYFKRSEIEIIVDIGLGQGHATVWTCDLTHGYIQINADYRS
>NZ_CP022540.1|WP_094033727.1|796425_796824_-|8-oxo-dGTP-diphosphatase-MutT
MKIILVSAVALIDTDGRVLLGQRPEGKSMAGLWEFPGGKVEQGETPEAALIRELHEELGIETWSSCLAPLTFASHAYDDFHLLMPLFACRKWGGIVQSKEGQALKWVRAKDLRDYPMPPADIPLIPILRDWL
>NZ_CP022540.1|WP_094033725.1|793471_795964_+|translation-initiation-factor-IF-2
MSDNDGKKTLGVRGGARSGSVKQSFSHGRTKNVVVETKRKRVVVPKPGAGSGAGGGRAGQVGGSGGKRPAGISDAEMERRLKALQAAKARESEETAKREADEKARAEERERMRAEKELKEREKREAEEAAKAKAENEEREKREAEDAAKAAAVAAAAPAPKADDSARAKPTKGEPPRRAPERDDQNRNRGRGRDDGGRRSGKLTLNQALTGGEGGRQKSMAAMKRKQERARQKAMGGVQQREKIVREVKLPEAITVAELANRMAERVGDVVKSLMNAGIMATQNQSIDADTAELVIEEFGHRVTRVSDADVEDVIKEVEDKPEDLIGRPPVITIMGHVDHGKTSLLDAIRNAKVTAGEAGGITQHIGAYQVTTDNGAVLSFLDTPGHAAFTSMRSRGAQVTDIVVLVVAADDAVMPQTIEAINHAKAAKVPMIVAINKVDKPSANPTKVRTDLLQHEVIVEELSGDVQDVEVSAVTGQGLDALLEAIALQAEILELTANPDRAAEGAVIEAQLDVGRGPVATVLVQNGTLKQGDIFVVGEQFGKVRALINDKGDRVKEAGPSVPVEVLGLNGTPEAGDVLNVVSTEAQAREIAEYRANLAKEKRAAAGAATTLDQLMQKAKEDENVSELPIVVKADVQGSAEAIVQAMEKIGNDEVRVRVIHYGVGAITETDVGLAEASGCPVIGFNVRANAPARNSANQKGVEIRYYSVIYDLVDDVKAAASGLLSNEIRENFIGYAKIKEVFKVSNVGKVAGCLVTEGIARRSAGVRLLRDDVVIHEGTLKTLKRFKDEVSEVQSGQECGMAFENYDDIRPDDVIEIFERQEIERSLS
>NZ_CP022540.1|WP_094033724.1|792829_793462_+|RNA-binding-protein
MTRGGQAKDHSDGPERKCIATGEVQPKDGLIRFVLGPDDRIVPDLAGKLPGRGLYVAANRAAIEKAAAKGLFSRAMKQPVKAPDGLADLIEQMLVKRVVDLISLARKSGEAVTGYEKVKSWLQSEEARVLIQAEDGSGRGKSKLSTPYGGNYIGWLTADELGMAFGRQSVIHAALGSGGLVPRIVEEAQRLKGVRVVSDADRGGRGHRKG
>NZ_CP022540.1|WP_094033723.1|791193_792822_+|transcription-termination/antitermination-protein-NusA
MAITSANQLELLQTAEAVAREKMIDPGLVVEAMEESLARAAKSRYGAEMDIRVNIDRRTGKATFTRVRTVVEEEELENYQAELTVEQAKQYMADPQIGDVYSEEVPPVELGRIAAQSAKQVILQKVREAERDRQFEEFQDRAGTIINGVVKREEYGNVIVDVGRGEAILRRNEKIGRESYRPGDRIRCYIKDVRREARGPQIFLSRTDPQFMAELFKMEVPEIYDGIIEIKAVARDPGSRAKIGVVSYDSGIDPVGACVGMRGSRVQAVVNELQGEKIDIIPWNEDMPTFLVNALQPAEVSKVVLDEDAERIEVVVPDEQLSLAIGRRGQNVRLASQLTGLDIDIMTEEEESKRRQAEFELRTKLFMDALDVDEFFAQLLVSEGFTNLEEVAYVEQEELLVIDGVDEGTAEELQTRARENLEELARKALEHARELGVDDSLVNFEGLTPQMLEALAEDGIKTLEDFATCADWELAGGWTTEGGKRVKDDGLLEKFDVDLEEAQTMVMTARVLLGWVDPTEMEPEETDEEGDEDVTDEDTQEA
>NZ_CP022540.1|WP_094033722.1|790609_791188_+|ribosome-maturation-factor-RimP
MNELIAKTGMDRRLAEIVQPVIEDMGFDLVRIRLMGGQVPTLQIMAERPEGGIEVDECAEISTAVSAVMDVEDPILDTYTLEVSSPGIDRPLTRLKDFDTYEGYEAKLETSEMIDGRKRFRGVLAGIEGNEVLVNLDEGTVGLEFDWLTDAKLVLTDELIREMLKARKSAAALDEKKFDEIETEADASREED
>NZ_CP022540.1|WP_094033733.1|806663_808586_-|molecular-chaperone-DnaK
MGKVIGIDLGTTNSCVAIMDGSQARVIENAEGARTTPSIVAFTEDERLVGQPAKRQAVTNPENTVFAVKRLIGRRVTDGEVTKDKDIVPYKIVDGGNGDAWVEIRGEKYSPSQVSAFTLQKMKETAESYLGEEVTQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKEARTIAVYDLGGGTFDVTILEIDDGLFEVKSTNGDTFLGGEDFDMRIVNYLAAEFKKEHSVDLTKDKMALQRLKEAAEKAKIELSSATQTEINQPFISMGANGQPLHMVMKLTRAKLESLVGDLIKNSIKPCMAALKDAGISKDEIDEVVLVGGQTRMPKVMEEVTKFFGKEPHKGVNPDEVVAMGAAIQAGVLQGDVKDVVLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQVFSTAEDNQSAVTIRVFQGEREMAADNKMLGQFNLEDIPPSPRGMPQIEVTFDIDANGIVSVGAKDKATGKEQQITIQASGGLSEDDIDRMVKEAEENAEGDKARKELVEAKNQAESLIHSTEKSVEEHGDKVDPSTVEVIELALAALRDDLEKDDITADKLKSGIQNVTESAMKLGEAIYKAQADEGSDEPHGADASSGPAGDDDIVDADFEDLDDNKRA
>NZ_CP022540.1|WP_094033734.1|808811_809414_+|alpha-ketoglutarate-dependent-dioxygenase-AlkB
MSEPIRQKGFVIHPGFLDRAAQVKLVARLREVLAIAPLFTPRTRRGPMSVRMSAAGKYGWISDTRGYRYDTQHPDGMTWPAIPDEVTAIWEAVSDCPRAPECCLVNWYGEGARMGLHRDEDEADLTCPVVSVSLGDEGLFRMGNVERGGRTKSIWLKSGDVVVMGGAARLAHHGVDRIRFGSSTLLPNSGRINLTLRVVT
>NZ_CP022540.1|WP_157733391.1|809461_810073_-|SH3-domain-containing-protein
MAGVMRALCGLLLLGTAAAAQSDYPRLHDVVGVASNDVLNVRAGPGASFPIVGELAYDARAVEVIRAEGNWGMVNVPEAVGWAALRFLAPRADGDISTVQRLTCGGTEPFWNIDILPGQSATIKTPVNYEVGDTFSVGLMRRAYNPLEKWVLMGAYGARNLSVVVAKTYCNNGMSDNEFGFDATVIVTGTDGYVLSGCCELSE
>NZ_CP022540.1|WP_094033736.1|810078_810672_-|SH3-domain-containing-protein
MNKFAVLLICLAGAASAQEFPALYHVTGVEEGDVLNMRTRPTENGTVIGALGFDAEHIEVVEEDDGWGRVNVEGLSGWVPLDSMERQDGTELPAGYQFKCFGTEPFWSATVVGENLSFTRPDDDDKAFKVGELSTAISRDAPHALLGSKLGENVTLVLNHTQCTDGMSDYVFGFSGSVVIGGYDTQVYTGCCSLDMK
>NZ_CP022540.1|WP_094036910.1|810720_811551_-|ABC-transporter-permease
MFQVTRPRSRLESFVYILELIYHNSVRSVRKTHGNAFMAIFMNMLQTIIFVLAFYFMFQILGMRSAALRGDFMVYIMTGVFLFMTHTKTLGAVSSSEGPASPMMQHAPMNTAIAIISAMVSTLYIQILSLFAILFVYDVAFNPFVMEDIHDPIGCLAMVILSWFSGAAIGLVFLAVKPWFPTPVSIISTVYQRANMIASGKMFVANTLPSSMLAMFDWNPLFHTIDQSRGYAFVDYNPRNSDWEYAFYLSIILVMIGLMGEFYTRKHASASWSARR
>NZ_CP022540.1|WP_094033737.1|811677_812475_+|3'(2'),5'-bisphosphate-nucleotidase-CysQ
MNYSELTTVMRRLALEAGEKIMEIYNSDDFEVMVKSDDSPVTVADQAADALISDGLRAAFPDTALVTEEQADSHDVTAKTFLIVDPLDGTKEFIKRRGDFTVNIALVEDGVPTRGVVYAPAKGRMFYTDSVGNSVEEAGPFDLETRGETKPIKVTAPKNDSLMVVASKSHRDQATDDYIAKYDVKDMTSAGSSLKFCLVATGEADLYPRLGRTMEWDTAAGHAVLNGAGGRVVRFDDHTALAYGKEGFANPFFIAYAPGVDLKEG
>NZ_CP022540.1|WP_094033738.1|812483_813707_+|glycosyltransferase
MTLPVSIVIVSRGRPAALMRCLTGVGQLDYALFEIVVVACPAGADATAARPDANHIKLIRFDEPNISAARNLGIAAASGEITAFIDDDAVPEPLWLRHLTGPFDDPQVACAGGYVIGRNGISFQWTSRSVDKTGDAHPLALTGDAPAKPTPPQGQAIKTEGTNMAVRRDVLSALGGFDPAFRFYLDETDLNLRLTAAGHRTALVPMAQVHHGYAESARRARDRSPRDLTEIGASQMVFLRKHCSETDRDAAWRTFADGQRARLLRFMQSGQLDPSDVARLMRGLRRGAQDGTSRKFGATPALPPPDQRFLPYPGRPDAPRVCLAGRPWQAARQRVKAAQAVRDGAIVSLFLFSPTVRRHRVSFTSDGVWEQSGGLFGQSDRDSPAIRLQLFSSRLSSEIMRVRKQRG
>NZ_CP022540.1|WP_094036911.1|813847_814738_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKKVTKAIFPVAGLGTRFLPATKSVPKEIMTLVDRPLVQYAIDEARAAGIEEFIFVTSRGKGALEDYFDVAPQLEEELRRKGKDQLLDILLSTNMDSGEIAYIRQHKALGLGHAIWCARRLIGDQPFAVMLPDDVIAAEKPCLQQMVEAYEQTGGCMVAAMEVPQDRVSAYGVLDISEDMGQMVKVKGMVEKPPADQAPSNLAVIGRYILTPDVFKHLENPQTGAGGEIQLTDAIDKEINGSGVYGYRFNGQRFDCGSKAGFLQATVAFGLARNELKGDLGAYLDELAISRKAAE
>NZ_CP022540.1|WP_094033739.1|814743_815727_+|UDP-glucose-4-epimerase-GalE
MAHVLVTGGAGYIGSHACKALRAAGYTPVTYDNLSTGWQDAVKFGPFEQGALSDRARLDEVFAKWQPVAVMHFAALSQVGEAMAKPGLYWRNNVEGSLTLIEAACAAGCLDFVFSSTCATYGEHDNVVLDENTPQEPLNAYGASKRAVENILRDFGASHGMKSVIFRYFNVAGADPEGEVGEYHRPETHLIPVMLEAVDGKRPGLTVHGTDYDTPDGTCIRDYVHVMDLVDAHILGLRWLQDGKGSRVFNLGTGRGFSVREVIDAAGHVTNMAVPCTDGPRRAGDATKLVSGSTRADEELGWSPARSTMPQMIADAWRWHKNGHYTA
>NZ_CP022540.1|WP_094033740.1|815707_816895_+|glycosyltransferase-family-4-protein
MVTTQRNRLLDLTRLTSRAGRPLTGVDRVEFAYLTHMLRHGPLWGLVRTSLGYVLLDAVGCAAFRDKVLSGDWGPADRLSRIKRGLDPMRAHAESDLRRICTARCLPLRLSPMLRRHLPPGITYVNTGHTNLTDRVLSALRSIGARVSVFVHDTIPLDVPQYQRLGTVEKFRHFLTRAAESADLIICNSHQTETDLGRHLAEDRVPPTISAPLGLDLTQPTVAPQGPWTTPYFVTLGTIEPRKNHALLLDLWDDIPDAHLLICGSRGWENHAVFDRLDTRPPRVHELPGLDDGQVAALLQRSAGLLFPSFAEGYGLPPVEAAALGAPVLVNDLPIYREVLGDIPVYANVSDRYLWRKEINRMAADHPSDQTRAEQAQRFAPPTWEAHFKAVLTLT

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Crispr_ID: NZ_CP022540_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022540_2

4347834-4348104

Orphan

Consensus_repeat	Method
GACCCAACCGAAATGTGAGGTCCCTCTCCTCCTCCCTGGGACCAAACATTCGCGGCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP022540_2

>merge|NZ_CP022540|2|4347834-4348104|PILER-CR
GACCCAACCGAAATGTGAGGTCCCTCTCCTCCTCCCTGGGACCAAACATTCGCGGCGATGCCTCTCCTCCTCCCTGGCATCGCCGCACGCTATTTCCGGGTCCCGATGACCCGACACGCAATGTGAGGTCCCTCTCCTCCTCCCTGGGACCAAACATTCGCGGCGGCACCTCTCCTCCTCCCTGGTGTCGCCGCACCTAATTCCGGGTCCCGATGACCCAACCGAAATGTGAGGTCCCTCTCCTCCTCCCTGGGACCAAACATTCGCGGCG

>NZ_CP022540|2|1|4347834-4348104|PILER-CR
GACCCAACCGAAATGTGAGGTCCCTCTCCTCCTCCCTGGGACCAAACATTCGCGGCG	ATGCCTCTCCTCCTCCCTGGCATCGCCGCACGCTATTTCCGGGTCCCGATGACCCGACA
CGCAATGTGAGGTCCCTCTCCTCCTCCCTGGGACCAAACATTCGCGGCGGCACCTCT	CCTCCTCCCTGGTGTCGCCGCACCTAATTCCGGGTCCCGATGACCCAAC
CGAAATGTGAGGTCCCTCTCCTCCTCCCTGGGACCAAACATTCGCGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022540.1\|WP_094036512.1\|4363251_4363758_-\|CarD-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224248
NZ_CP022540.1\|WP_094036506.1\|4355658_4357107_-\|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223246
NZ_CP022540.1\|WP_094036508.1\|4357582_4358683_-\|GTP-cyclohydrolase-I-FolE2	unknown	unknown	gnl\|CDD\|237466
NZ_CP022540.1\|WP_094036495.1\|4336193_4337222_+\|histone-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|212525
NZ_CP022540.1\|WP_094036505.1\|4354072_4355659_-\|5-guanidino-2-oxopentanoate-decarboxylase	unknown	unknown	gnl\|CDD\|236041
NZ_CP022540.1\|WP_094036497.1\|4340481_4342668_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|237425
NZ_CP022540.1\|WP_094036510.1\|4360252_4361179_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|310523
NZ_CP022540.1\|WP_094036496.1\|4337380_4340230_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|237425
NZ_CP022540.1\|WP_094036504.1\|4348449_4351524_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP022540.1\|WP_094036498.1\|4342849_4344016_+\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NZ_CP022540.1\|WP_094036501.1\|4345912_4346977_-\|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455
NZ_CP022540.1\|WP_094036499.1\|4344012_4344660_+\|dTMP-kinase	unknown	unknown	gnl\|CDD\|184429
NZ_CP022540.1\|WP_094033518.1\|4351745_4352996_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP022540.1\|WP_157733596.1\|4346990_4347146_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022540.1\|WP_094036509.1\|4358810_4360004_-\|O-succinylhomoserine-sulfhydrylase	unknown	unknown	gnl\|CDD\|168979
NZ_CP022540.1\|WP_094036503.1\|4347199_4347418_+\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|368980
NZ_CP022540.1\|WP_094036507.1\|4357200_4357428_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022540.1\|WP_094036500.1\|4344656_4345805_+\|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl\|CDD\|236022
NZ_CP022540.1\|WP_094036494.1\|4335196_4336123_+\|3-keto-5-aminohexanoate-cleavage-protein	unknown	unknown	gnl\|CDD\|377562
NZ_CP022540.1\|WP_094036511.1\|4361301_4363176_+\|potassium-transporter	unknown	unknown	gnl\|CDD\|235131

Protein	Function_ID	Function_description	E-value
NZ_CP022540.1\|WP_094036512.1\|4363251_4363758_-\|CarD-family-transcriptional-regulator	gnl\|CDD\|224248	COG1329, COG1329, Transcriptional regulators, similar to M. xanthus CarD [Transcription].	1.33043e-64
NZ_CP022540.1\|WP_094036506.1\|4355658_4357107_-\|TrkH-family-potassium-uptake-protein	gnl\|CDD\|223246	COG0168, TrkG, Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	3.97398e-101
NZ_CP022540.1\|WP_094036508.1\|4357582_4358683_-\|GTP-cyclohydrolase-I-FolE2	gnl\|CDD\|237466	PRK13674, PRK13674, GTP cyclohydrolase I FolE2.	1.05629e-130
NZ_CP022540.1\|WP_094036495.1\|4336193_4337222_+\|histone-deacetylase-family-protein	gnl\|CDD\|212525	cd10001, HDAC_classII_APAH, Histone deacetylase class IIa. This subfamily includes bacterial acetylpolyamine amidohydrolase (APAH) as well as other Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. Mycoplana ramosa APAH exhibits broad substrate specificity and catalyzes the deacetylation of polyamines such as putrescine, spermidine, and spermine by cleavage of a non-peptide amide bond.	1.50899e-148
NZ_CP022540.1\|WP_094036505.1\|4354072_4355659_-\|5-guanidino-2-oxopentanoate-decarboxylase	gnl\|CDD\|236041	PRK07524, PRK07524, 5-guanidino-2-oxopentanoate decarboxylase.	4.77964e-156
NZ_CP022540.1\|WP_094036497.1\|4340481_4342668_+\|PAS-domain-containing-protein	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.34384e-103
NZ_CP022540.1\|WP_094036510.1\|4360252_4361179_+\|alpha/beta-hydrolase	gnl\|CDD\|310523	pfam05990, DUF900, Alpha/beta hydrolase of unknown function (DUF900). This family consists of several hypothetical proteins of unknown function mostly found in Rhizobium species. Members of this family have an alpha/beta hydrolase fold.	7.59557e-06
NZ_CP022540.1\|WP_094036496.1\|4337380_4340230_+\|PAS-domain-containing-protein	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	1.10764e-114
NZ_CP022540.1\|WP_094036504.1\|4348449_4351524_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP022540.1\|WP_094036498.1\|4342849_4344016_+\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	1.01629e-113
NZ_CP022540.1\|WP_094036501.1\|4345912_4346977_-\|Mrp/NBP35-family-ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	4.58462e-132
NZ_CP022540.1\|WP_094036499.1\|4344012_4344660_+\|dTMP-kinase	gnl\|CDD\|184429	PRK13973, PRK13973, thymidylate kinase; Provisional.	1.55709e-87
NZ_CP022540.1\|WP_094033518.1\|4351745_4352996_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	1.02019e-60
NZ_CP022540.1\|WP_094036509.1\|4358810_4360004_-\|O-succinylhomoserine-sulfhydrylase	gnl\|CDD\|168979	PRK07504, PRK07504, O-succinylhomoserine sulfhydrylase; Reviewed.	0
NZ_CP022540.1\|WP_094036503.1\|4347199_4347418_+\|DUF1127-domain-containing-protein	gnl\|CDD\|368980	pfam06568, DUF1127, Domain of unknown function (DUF1127). This family is found in several hypothetical bacterial proteins. In some cases it represents it represents the C-terminal region whereas in others it represents the whole sequence.	6.4457e-06
NZ_CP022540.1\|WP_094036500.1\|4344656_4345805_+\|DNA-polymerase-III-subunit-delta'	gnl\|CDD\|236022	PRK07471, PRK07471, DNA polymerase III subunit delta'; Validated.	1.12874e-152
NZ_CP022540.1\|WP_094036494.1\|4335196_4336123_+\|3-keto-5-aminohexanoate-cleavage-protein	gnl\|CDD\|377562	pfam05853, BKACE, beta-keto acid cleavage enzyme. BKACE, beta-keto acid cleavage enzyme plays, a role in lysine degradation. In certain instances it catalyzes the conversion of 3-keto-5-aminohexanoate and acetyl-CoA into acetoacetate and 3-aminobutyryl-CoA. The family is found to have at least 14 slightly different potential new enzymatic activities, all of which can therefore be designated as beta-keto acid cleavage enzymes.	7.5258e-143
NZ_CP022540.1\|WP_094036511.1\|4361301_4363176_+\|potassium-transporter	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0

>NZ_CP022540.1|WP_094036503.1|4347199_4347418_+|DUF1127-domain-containing-protein
MALATANITKAHGGLGARFANLVEALQARAARRKIYRETYSELASLSNRDLADLGLARSEIGRIAWQAANEI
>NZ_CP022540.1|WP_157733596.1|4346990_4347146_-|hypothetical-protein
MLQLHNGRIGNAAMQKLHMNDVHFFVERPMDAQKDGYGLCCRKVTATQNGM
>NZ_CP022540.1|WP_094036501.1|4345912_4346977_-|Mrp/NBP35-family-ATP-binding-protein
MSEIKTAVETVLKQVELPDGGNLISRDMIRALRVDGGVVRFVIEAQSAESAKRMEPLRQVAERAAASVAGVTSASAVLSAPTAGKAPPQLKVGGHAKPQEGVMKPAGVKTILAIGSGKGGVGKSTVSANLAVALARAGKRVGLLDADIHGPSQPRMFGLTAKPASPDGKTIIPLEAHGVTVMSIGSMLAEDKAVVWRGPMLMGALQQMLMQVEWGTKDVLIVDLPPGTGDVQLSLCQKSEVAGAIVVSTPQDVALLDARKALDAFATLNTPVLGLIENMAVFTCPHCGKDSHIFGHGGVVTEAEKMGLPLLAQLPIDLDTRLGGDGGQPIALGDSAMAQSYAQLADRLIKSGIV
>NZ_CP022540.1|WP_094036500.1|4344656_4345805_+|DNA-polymerase-III-subunit-delta'
MSDLADLPEPDRLTGAPHPRETARVIGQSEAEQTFLTAYTSGRLHHGWLLTGPRGTGKATLAWEIARFLLATPPDEGDGLFGAPPPPDTLHIDPEHPVARRMLALSEPGLFLLRRGGAGSTDTERDKALKEGRFSDVIRVDEIRKLNAFFGLSAADGGRRVVIVDSADEMTNQAANALLKMLEEPPARTTLLLLSHQPARLLPTIRSRCRTLRLAPLPPEDMAQALAQAGAEVAPNDVAPLTTLAEGSVGAAMRLLTLDGLALYREILKLLSGLPALDRAALLSLADSCAGKGKESRLDLVLTLADQLAARLARTGVTGHPPPEIMSGEGDMLTRLAPDPAAGRRWANVSQEAGDRARHARAVNIDPAALITDLFLHLQKAA
>NZ_CP022540.1|WP_094036499.1|4344012_4344660_+|dTMP-kinase
MNETNRPWPGLFISFEGIDGSGKSTQARRLSETLRNRGLNPVLTREPGGSPGAEEIRALVLQGDPDRWSAETELLLFTAARRDHLERVIRPALEAGRVVICDRFADSTRMYQGRGGLRDKVDALHNLMIGVEPDLTLLVDMPADAGLSRAKARATDEERFEDFGLALQQQMRDGFLALAQDHPNRFRVIDGNRDITTVATEILDTVTPYLPACPA
>NZ_CP022540.1|WP_094036498.1|4342849_4344016_+|D-alanyl-D-alanine-carboxypeptidase
MSIMSRSLLAATALVFAATASMAFDTRARAAFVLDQTTGTVLLTKEADQALPPASMSKLMTLYIAFEALRDGRLQRDERLPVSAHAMSFGGSTMFLDTTDRVKVEDLLRGVIVLSGNDACVVLAEALSPDGTEGGFARLMTQRAQQLGMTSSTFKNASGWPAQGHAMSMRDLVLLANLIISDFPEFYPMFSERVFEFDGRAPSNVNNRNPLLGLGIGADGLKTGHTQEAGYGLVGSATNGNRRVVFAITGLDSTRARAEEAEAIVNWAFRQFAEQTVVTKDKSVATAEVWMGSADEVHLVAEKDVTLLLPTMTAGGIKAEVVYTGPIEAPVAKGQKLAELIIQPEGLPETRVPLVAADKVDAGGFVDRIMTVSSLLIKRFSEDAGDAM
>NZ_CP022540.1|WP_094036497.1|4340481_4342668_+|PAS-domain-containing-protein
MVCDGHLMFIQILQNTALLCFAAVGLHLVWRHGELARSLVGKLLIGLSFGFVAFLVTATPVVLPDGATIDARAGPVILAGIVGGPVAAIIAGLLGALARGYFGGYFVFSGVVSYAAYALAGSALSMRYFTNALGTRLGPLRIAAASALSIFAASLMYFLITPQSVAIDWITQDFPVIAVANTLSIIMTGYVVHFAIEFAERKAKLISALKTLELAKSAGGIGIWEIDTRTGVASWDDINQNLHGLTLKDGKGTFDDWAKTLHPEDQPRVQKEFEAALSETEPFNTTYRVIHPDGSIRHLKGNAIIQRDEAGTPIRVVGANVDLTSAEAKDRALLQSQRVAAQAQKLDAIGKLTGGVAHDFNNLLAVIQGNLELLLQDQDEHHFPESERADILTSAISATRRGGELTRNMLAFARMSRLEPRRIKVNDLVRETETWLARAIPSSIEMETNLQHGLWQAELDPASLQSALVNTVVNARDAMPDGGKLTIETSNVRIDSDYIIDREEDVPPGRYVMLAVTDTGTGIPEDLLPTVFEPFVSSKDSSVGSGLGLSMVQGFVKQSRGFVRIYSEIDVGTSIKMFFPALDSPDQAEPVAQSAPPDSGQPEATGLARILIAEDQLEVLSMIVRTLTSAGYTVDAATNGQDAYDLFKANRSYDLLLTDVVMPGEMRGPDLARACRALEADLPVIFMSGYASEATVHGNGLRADDIRLMKPVPRVELLGSIERLLEKG
>NZ_CP022540.1|WP_094036496.1|4337380_4340230_+|PAS-domain-containing-protein
MPHVPSAPDVGYDQILRDLLTNRENRDLGPEQALAQLCKTLATTLDAHQAGLWTLNKATGALDAKFYWDRDTCDAENGADLPNGTADRPISEVDQDQIVAIADIRTDPRWAASAPNAMYSTELRAVLECPLRTPAGPAGVVSIGHRGAPRKWTAEDISFAAAVAGLISLAIERHDLIVAEKDARDHEHRLKVYTDLATDWFWETDSDFRFQRLHGKQARDGQIPKDYLGHKLWDVPILTPLEGTWDALKKRVDQRKRIFDFVVSASDGIGDRHYAEIAGLPKFNAAGEFEGYWGTAKDVTRRTQHELDLAESQTRDKTAARLVKLASWTWDKVEDRCSYCSPELAEMFGVTVDEFLRRSTSWEKDLDWYHPDDRERYAQASESATATQSGYDIIARVVLGDGTIRTVHETTEPVFDSSGAFVATMGVLLDITDKVELQDRLMIQEDRLKNIIDNIPGAAYRVKYDATFTNVYHSSGYLTHFVDPNTPPVKWQQDRNFPTLDIPAADRDRVEKSLRRAVLLNQCYSVEYPVTLRDGSQRWVSDRGRPVETSDGEIELEGIMLDATEKHAAQDALAHAQKLEAVGKLTGGIAHDFNNLLAVILGNLELLRDETEKPGQIDLIDAGIEAVRRGADLTRNMLAFARKSPLKLEVLNLNSLAGKTKNWIGRTLPANILVETSLLAGLWKIEADASATQSAILNLVLNARDAMPNGGKMTIETSNVRIDEEYIENRFEDMEPGRYVMLAVSDNGHGIPKDIVDDIFEPFFTTKPPGSGSGLGLSMILGFMKQSGGSVRVYSEPGVGTTFKLFFKALHSDTLISDVPNAGLPLAQGAARILLVEDNTGVLAVLRSTLTRAGYDIKTASSGDLARDIFEANPDFDLLLTDIVMPGALQGTALAKALREIRPDLKVIFMSGYASEATVHGNGLRPEDIRLMKPIGRTVLFQAIEKALG
>NZ_CP022540.1|WP_094036495.1|4336193_4337222_+|histone-deacetylase-family-protein
MKAIFDDRQWKHQPRHFMANGAILPNPEQAERIDRLLTGAQAAGCTVEAPKDAGLAPIAALHSPEYLTFLENIHTRWRRIEGAGDEVIPNIHPANRTDSYPKSAVGQAGYHQADTACPIAAGTWEAAYWSAQSAVTGADLILRGETSAYVLSRPPGHHAFGDLAGGFCFLNNSGIAAERLRAQGLRPAILDVDVHHGNGTQGIFYDRDDVLTVSIHADPERFYPFFWGQAHERGTGPGLGYNLNLPLARGTTDDAYLATLDVALRRIRSFGADVVVVALGLDAFVDDPFKGLAVTTTGFSRIGAAIAGLNLPCLFVQEGGYLCDELADNLTAVLTGHQEHSA
>NZ_CP022540.1|WP_094036494.1|4335196_4336123_+|3-keto-5-aminohexanoate-cleavage-protein
MSKIIITCAVTGSIHTPSMSPHLPITAQQITDNAIGAAEAGATILHLHARDPENGRPSADPAHFMAFLPQIKQRCGAVLNISTGGSATMPLEDRLAAPKQAEPEMCSLNMGTMNFALFPAVDKITDWKFDWEKPFLEDSEDLVFKNTPRDMAYILHELGEKRGARFEFECYDLSHLYMLKHFVDRGLVRGPLFIQFVFGVLGGMGPDPENLTHMKMIADRLFGDTYTFSVLAAGRHQMPLVTMSAILGGHVRVGLEDSLMISRGVLARNNAEQVAKIRRIVEDLGRTVATADEAREMLHLKGADRTAI
>NZ_CP022540.1|WP_094036504.1|4348449_4351524_+|valine--tRNA-ligase
MPLEKSFNAAEAEPRLTAKWLDTGAFRAGANRSRDESFTIMIPPPNVTGALHVGHAFNNTLQDILTRWHRMRGFDTLWQPGQDHAGIATQLQVEKKLKAEEGKRRTDLTRPEFLDKVWEWKGQYGGTIINQLQRLGCSCDWDRNAFTMAGAPGDPKTGHENSPNFHDAVIKVFVDMFDKGLIYRGKRLVNWDPHFETAISDLEVENIETPGHMWHFKYPLAGGVTYMYEEKDEEGKTVFSEERDYISIATTRPETMLGDGAVAVHPSDERYASIVGQLCEIPVGPKEHRRLIPIITDEYPDPTFGSGAVKITGAHDFNDYQVAKRGGIPMYRLMDTRAQMRDDGAPYAEAAAIAMKVAQGKQTLTEAEADAINLVPDHLRGLDRFEAREKVIAEITAEGLAVMTTSDDPRLGPQKKLKKGEEPPAVTPAPLVESKPIMQPFGDRSKVVIEPMLTDQWFVETSEIVGPALDAVRSGDIKIMPESGEKVYYNWLDNIEPWCISRQLWWGHQIPVWYIPGEEDWYPICAANESEALDKARAISAEGTEFRIVENAQEAAEVLEDLREHMHLRTEGRIRTADSPAQLPMFRDPDVLDTWFSSGLWPIGTLGWPEQTDELKRFFPTSVLITGQDILFFWVARMIMMQLAVVDQIPFHTVYLHQLVRDEKGKKMSKTTGNVIDPLEIVDDYGADALRFTNASMASIGGVLKLSVDRIAGYRNFGTKLWNACRFAEMNGVFEGHATRAEAPQAAQTVNKWILGETARVRETVDLALTEYRFNDAANALYAFTWGKVCDWYVEFAKPLFDAQDEAVVAETRQTMAWVLDQCLTLLHPIMPFITEELWDTLGARSKLLVHADWPTYAAADMVDPAAEAEMSWVIALIEGVRSARAQMHVPAGLYVPMLVKGISADEQAAWDRNEVLIKRLARIEGLEAVADFPKGCVTVPVGNATFGLPLADIIDVGEEKARLEKTLGKLGKEIGGLKGRLNNPKFAVSAPPEVVEEAQENLRLREGEEAKLKEALARLAEIG
>NZ_CP022540.1|WP_094033518.1|4351745_4352996_+|IS256-family-transposase
MQENTITQLSDPSGISPDPLTDLIRDGARKLIEQAIEAELSTLLGAFADHKLEDGRARLVRHGHLPEREILTGVGPVAVTVPRVRDRKPGTDKIAFTPSILPRYLRKAKSVEELLPWLYLKGVSTGDFSEALAALLGPHAKGLSATTITRLKADWWSEYEAWEKRDLGTRRFLYIWADGVYFKPRRAEEKQCVLVIVGADEYGRKELLAMTDGFRESTQSWREVLLDLKRRGLKQDPKLAIGDGALGFWAALREVFPSTQEQRCWLHKTMNVLNALPKSVQAKAKAHLHDIWQAETRAAASAAFDFFVDAYGVKWDKAVAKLVKDRDALLTFYDYPAEHWKHIRTSNPIESTFATVRHRTKRTKGCLSRKTGLAMAFRLMMSAQTKWRKLDGRNRLPEVISGVEFRDGVRQLQNAA
>NZ_CP022540.1|WP_094036505.1|4354072_4355659_-|5-guanidino-2-oxopentanoate-decarboxylase
MQKPLGAQISHALKARGVEVIFGIPGVHNVEMYRGIEEAGITHVLARHEQGAGFMADGYARASGRPGVCYLITGPGFVNAMTALGQAYSDSVPVLALASCLDEVAARRGQLHQMRDQRAAGATVCDWSETASDPTAVFALIDRAFGEFASARPRPKALHVPIAALGALADPAPEPPLRPEVPHLTHDQIYAVIDALTEAEKPLFVFGGGAAAGAEYVPALLQQTGAASFVTYAGRGIVPADQPLFFGSFLARPDSARIAAEADLVVALGTELSEVDLWRDRLGNTGRTIRVDLDPEVLSGLRAGDMGFVGDAAALMKALTIAIPARNDDRTACWDAGRVAETRRRWRGEIMAERPGIVEVAETLRAAMPDDAMIYSDMTQLAYGGKEVWDMPRAGHWHHPSGFGTLGYALPAAIGGAVARKGLPTCAIMGDYGLQYTLPELGTAVELGLPLPILVWDNGSLGEIRDSMVASQIAPNAVVARNPDFLALARAYGAGSVEPSDLEGLQAALVEAFQAEGPTVIRMTPALV
>NZ_CP022540.1|WP_094036506.1|4355658_4357107_-|TrkH-family-potassium-uptake-protein
MFDVRPVAYVIGLLVACLGGTMLLPLVVDLAEGRGEWPVFLESASITILAGGLTSLACSNAVKEGLTLQQTFLLTTGVWVALPVFGALPFVLGATDASYTDALFEAMSGLTTTGSTVFTGLDDLPKGLLLWRGLLQWLGGIGIIVVAMVFLPELRVGGMQIFRSEAFDTMGKILPRATQISASISSIYISLTLFCTIFYLFCGMNAFDATVHAMTTVSTGGFANYDVSFAVFAGPAEYVASVFMVLAALPFVRYVQMVAGHRFVLFRDSQVVTFVTIIAVLVVVTASILLSIFPHHPEQAVREALFNITSIMTGTGFSSVDYMTWGPFLVAMFFFIGLIGGCAGSTACSVKIFRYQLLFASIRVQLRRIRAPHGVFVPRYEGRPVGPDVMSSVMSFFVFFVVTLGVLSVALSLTGLDFITSVSGAATAIANIGPGLGDKIGPTGNFAGLSDTAKWILTFAMLVGRLELLAVFALFTIGFWRA
>NZ_CP022540.1|WP_094036507.1|4357200_4357428_-|hypothetical-protein
MTRDNIQIGMGHRSLNTRIDVYLSEVGFGLNPAQLRRARLRQIITLECASDAELASLGIRRDDILPFVFRDLLAA
>NZ_CP022540.1|WP_094036508.1|4357582_4358683_-|GTP-cyclohydrolase-I-FolE2
MNIHTPAIDRKPSKEEAAEALALLRRWASKAHDAEIAALDPIVGRLTPDATPETYPAFARVYPEGFSVDAAYKDTLPDLQNGPSSLIRGANRAIQHVGISNFRLPIQYRTRDNGDLRLETSVTGTVSLEADKKGINMSRIMRSFYAHAEKTFSFEVIEAALDDYKSDLESFDARINMRFSFPMKVDSLRSGLSGYQYYDIALELVERDGVRRKVMHLDYVYSSTCPCSLELSEHARQTRGQLATPHSQRSVARISVELREGDCLWFEDVVDMCRRAVPTETQVMVKREDEQAFAELNAANPIFVEDAARLFAEQLQADERVGDYRVVASHQESLHSHDAVSVLTEGDLFAADSLDPKLFSTLFHVG
>NZ_CP022540.1|WP_094036509.1|4358810_4360004_-|O-succinylhomoserine-sulfhydrylase
MTIDNGQPFGKATNLVHGGTKRSQWGEVSEAIFLTQGFVYDTAEAAEARFLKAGEDEFIYARYGNPTVAMFEERMALLEGAEDGFACASGMAAVNGALTSMLKAGDHVVSARALFGSCLYILEDVLTRYGVEVTFVDGADLAQWEAALRPETKAVFFESMSNPTLELVDIEAVAALAHKVGATVVVDNVFSTPVYSKAIAQGADLVVYSTTKHVDGQGRCLGGVILGTREHIRGVVEPYMKHTGGSMSPFNAWIMLKGLETVGLRVRAQTEGAVALAEALADHPKVSRMIYPGHASHPQHALVQRQLGAGGTLVSFEVVGGKEAAFRLLNALQIVIISNNLGDAKSIATHPATTTHQRLKPEQRASLGIGDGMIRLSVGIEDPADIVRDVKQALDVV
>NZ_CP022540.1|WP_094036510.1|4360252_4361179_+|alpha/beta-hydrolase
MPMLCVTVTDSDPRLHGDDVPLQPALAAALAADSGPVTIMVHGYKYQPGHPIHCPHGTLMSPEPRNGDWKIVSWPERLGLHGQRGQGLAISFGWRARGSIWAAHRRAEAAGHALAALVREIRQYAPTRRINVVAHSLGARVALTAIRVGPCGAITRAVLLAAAEYGEIASQTLDSPSGRLTEVLNVTTRENDLYDFMLECLVPPQRRGDRMLGHGGLRHPRLVTLQLDDTRSLAALRHAGFPIAAPERLICHWSPYLRKGVFPLYRAVLTGAMPLDRLRALLPDDCAPRWSRLRLRLPRPQPRLLPAE
>NZ_CP022540.1|WP_094036511.1|4361301_4363176_+|potassium-transporter
MDSFLFQASVFLLAAVIAVPLATRLGLGSVLGYLLAGLVIGPGLGLVVDTADIQHYAEFGVVMMLFLIGLELEPRALWGMRHRLIGLGGLQVTLTTCAILAGAMALGLAWPTALAVGLALALSSTAIVLQTLNEKKLMQTNGGRSAFSVLLTQDIAVIPMLVIFPLLSVAAFVSPAQFLNNVDDHAAEAHHASLSLVEGLPGWGAALVTLGVIAAIILAGAYGARPLFRYVHAARLPEMFTAVALLIVIGIAFLMILVGLSPALGTFLAGVVLANSEFRHQLESDVEPFKGLLLGLFFITVGAGIDVDALLAEPLTILGIALAVILIKGAILYGLGRSFGLRKRGLWLFTLGLAQAGEFGFVLISFGRQQNVFPDVLGDRLLLVIAMTMLITPLLFLFFDHLNKGFSKVTEDPTEDTIDEEGPVIIAGIGRFGQIVNRLVRSAGHRTVVLDHDIKTIQLMRRFGVKGFFGDPTRPELMHAAGIETARVLVAALDDPKATTKLVAYARRVRPDLHIVARARDRMHVYALYQAGANDIVREMFDSSLRAGRYVLENVGMTEFEAAIAEETFYHHDRKTIQELAELWDPSVPQAENAAYVARSKELERELETELYTALAARGKQDAA
>NZ_CP022540.1|WP_094036512.1|4363251_4363758_-|CarD-family-transcriptional-regulator
MTKTKKADFRPNEYVVYPAHGVGQIVSIEKQEIAGINLELFVISFEKDKMTLRVPTHKATEVGMRSLSSPDVVDEAMRTLRGKAKVKRAMWSRRAQEYEQKINSGDLIAIAEVVRDLHRADDQREQSYSERQLYEAALERLTREVAAVSGDETAAAKQVDDVLSLRAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NZ_CP022540_2	2.1\|4347891\|59\|NZ_CP022540\|PILER-CR	4347891-4347949	59	NZ_CP022540.1	4347677-4347735	1.0
NZ_CP022540_2	2.1\|4347891\|59\|NZ_CP022540\|PILER-CR	4347891-4347949	59	NZ_CP022540.1	4348105-4348163	1.0
NZ_CP022540_2	2.2\|4348007\|49\|NZ_CP022540\|PILER-CR	4348007-4348055	49	NZ_CP022540.1	4347785-4347833	1.0

1. spacer 2.1|4347891|59|NZ_CP022540|PILER-CR matches to position: 4347677-4347735, mismatch: 0, identity: 1.0

atgcctctcctcctccctggcatcgccgcacgctatttccgggtcccgatgacccgaca	CRISPR spacer
atgcctctcctcctccctggcatcgccgcacgctatttccgggtcccgatgacccgaca	Protospacer
***********************************************************

2. spacer 2.1|4347891|59|NZ_CP022540|PILER-CR matches to position: 4348105-4348163, mismatch: 0, identity: 1.0

atgcctctcctcctccctggcatcgccgcacgctatttccgggtcccgatgacccgaca	CRISPR spacer
atgcctctcctcctccctggcatcgccgcacgctatttccgggtcccgatgacccgaca	Protospacer
***********************************************************

3. spacer 2.2|4348007|49|NZ_CP022540|PILER-CR matches to position: 4347785-4347833, mismatch: 0, identity: 1.0

gcacctctcctcctccctggtgtcgccgcacctaattccgggtcccgat	CRISPR spacer
gcacctctcctcctccctggtgtcgccgcacctaattccgggtcccgat	Protospacer
*************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1026979 : 1038172

Bacillus_phage(16.67%)

protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094033897.1\|1026979_1030363_+	double-strand break repair helicase AddA	U5PSZ2	Bacillus_phage	3.9e-06	56.9
WP_094033898.1\|1030429_1030750_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	1.1e-19	46.9
WP_094033899.1\|1030847_1031402_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_094033900.1\|1031449_1032757_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A2H5BJT2	Erwinia_phage	9.4e-41	28.7
WP_094033901.1\|1032942_1034169_+	glutathionylspermidine synthase family protein	B2ZXR7	Ralstonia_phage	6.1e-74	38.8
WP_094033902.1\|1034215_1034797_+	DUF1190 domain-containing protein	M1F298	Cronobacter_phage	3.8e-10	29.3
WP_094033903.1\|1034899_1036453_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094033904.1\|1036522_1038172_-	ABC transporter ATP-binding protein	A0A1M7XV31	Cedratvirus	4.9e-10	25.1

DBSCAN-SWA_2

3094412 : 3116581

Paracoccus_phage(27.27%)

head,portal,tail,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094035543.1\|3094412_3094997_-\|protease	TIGR02281 family clan AA aspartic protease	NA	NA	NA	NA
WP_094035544.1\|3095057_3095678_-	MarC family protein	NA	NA	NA	NA
WP_094035545.1\|3095851_3097711_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	7.3e-71	34.3
WP_094037151.1\|3097915_3098338_+	nucleoside-diphosphate kinase	NA	NA	NA	NA
WP_094035546.1\|3098423_3099146_-	hypothetical protein	NA	NA	NA	NA
WP_094037152.1\|3099186_3099831_+	hypothetical protein	NA	NA	NA	NA
WP_094035547.1\|3099899_3100241_-	TfoX/Sxy family protein	NA	NA	NA	NA
WP_094035548.1\|3100237_3101041_-	isocitrate lyase/phosphoenolpyruvate mutase family protein	NA	NA	NA	NA
WP_094035549.1\|3101033_3102224_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_157733522.1\|3102483_3102855_+	hypothetical protein	NA	NA	NA	NA
WP_094035551.1\|3102868_3104146_+	DNA-packaging protein	A0A1V0DY66	Dinoroseobacter_phage	2.2e-74	40.0
WP_094035552.1\|3104342_3105542_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	1.4e-59	35.8
WP_094035553.1\|3105534_3105762_+	hypothetical protein	NA	NA	NA	NA
WP_094035554.1\|3105842_3106382_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	2.4e-30	48.1
WP_094035555.1\|3106410_3107592_+\|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	3.2e-64	41.4
WP_094035556.1\|3107749_3108343_+	hypothetical protein	NA	NA	NA	NA
WP_094035557.1\|3108339_3108675_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_094035558.1\|3108671_3109079_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_094035559.1\|3109101_3109509_+\|tail	phage major tail protein, TP901-1 family	A0A1Q1PW44	Pseudoalteromonas_phage	4.4e-05	33.9
WP_094035560.1\|3109508_3109841_+	gene transfer agent family protein	NA	NA	NA	NA
WP_094035561.1\|3109827_3110016_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_094035562.1\|3110027_3110687_+\|tail	phage tail tape measure protein	A0A1B2AP03	Escherichia_phage	8.7e-11	38.5
WP_094035563.1\|3110697_3111330_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	1.8e-61	52.2
WP_094035564.1\|3111329_3112214_+	DUF2163 domain-containing protein	A0A1V0DY93	Dinoroseobacter_phage	4.1e-56	40.1
WP_094035565.1\|3112210_3112642_+	peptidase	F4YXU4	Roseobacter_phage	1.0e-28	47.5
WP_094035566.1\|3112645_3116581_+	host specificity protein	A0A0B5A7K5	Paracoccus_phage	7.8e-224	39.3

DBSCAN-SWA_3

3994377 : 4053948

Acidithiobacillus_phage(28.57%)

protease,transposase,integrase

attL 3989648:3989662|attR 4035800:4035814

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3989648:3989662	attL	NA	NA	NA	NA
WP_094036239.1\|3994377_3995559_+\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	3.1e-75	41.4
WP_094036240.1\|3995563_3996445_+	hypothetical protein	NA	NA	NA	NA
WP_094036241.1\|3996532_3996739_+	hypothetical protein	NA	NA	NA	NA
WP_094036242.1\|3997251_3997770_+	hypothetical protein	NA	NA	NA	NA
WP_157733576.1\|3997958_3998477_+	hypothetical protein	NA	NA	NA	NA
WP_094036244.1\|4000070_4000904_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_094036245.1\|4001123_4001960_-	hypothetical protein	NA	NA	NA	NA
WP_094036246.1\|4002150_4002942_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_157733577.1\|4005624_4007226_-	hypothetical protein	NA	NA	NA	NA
WP_094036249.1\|4007418_4008645_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_157733578.1\|4008696_4010793_+	hypothetical protein	NA	NA	NA	NA
WP_157733579.1\|4010869_4011139_-	hypothetical protein	NA	NA	NA	NA
WP_157733580.1\|4013277_4013817_-	hypothetical protein	NA	NA	NA	NA
WP_094036253.1\|4014124_4014850_-	DUF1499 domain-containing protein	NA	NA	NA	NA
WP_094036254.1\|4014926_4016285_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_094036255.1\|4016281_4019389_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_094036256.1\|4019392_4020571_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_094036257.1\|4020640_4021240_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_094036259.1\|4022027_4023062_+	fatty acid desaturase	NA	NA	NA	NA
WP_094036260.1\|4023510_4024530_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_094033518.1\|4027956_4029207_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.0e-101	49.6
WP_094036261.1\|4030816_4031461_-	HyuE hydantoin racemase	NA	NA	NA	NA
WP_094036262.1\|4031463_4031961_-	nucleoside deaminase	NA	NA	NA	NA
WP_094036263.1\|4031950_4032925_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	3.2e-17	33.0
WP_094036264.1\|4032921_4033914_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-19	29.5
WP_094037242.1\|4033910_4035347_-	amidohydrolase family protein	NA	NA	NA	NA
WP_094037243.1\|4035358_4036540_-	amidohydrolase family protein	NA	NA	NA	NA
4035800:4035814	attR	NA	NA	NA	NA
WP_094037244.1\|4036545_4037502_-	ABC transporter permease	NA	NA	NA	NA
WP_094036265.1\|4037515_4038499_-	ABC transporter permease	NA	NA	NA	NA
WP_094036266.1\|4038629_4040207_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094036267.1\|4040372_4041062_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_094036268.1\|4041058_4041733_+	flavin reductase family protein	NA	NA	NA	NA
WP_094036269.1\|4042323_4042767_-	site-specific recombinase	K4ICM1	Acidithiobacillus_phage	1.1e-17	39.0
WP_094036271.1\|4043818_4044331_-	hypothetical protein	K4HZY1	Acidithiobacillus_phage	8.8e-43	61.0
WP_094036272.1\|4044349_4044484_-	hypothetical protein	NA	NA	NA	NA
WP_157733581.1\|4044622_4044850_-	hypothetical protein	NA	NA	NA	NA
WP_157733582.1\|4045065_4045227_+	hypothetical protein	NA	NA	NA	NA
WP_094036274.1\|4045267_4045546_-	hypothetical protein	NA	NA	NA	NA
WP_094036275.1\|4045701_4046625_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_094036276.1\|4046769_4047606_+	DUF481 domain-containing protein	NA	NA	NA	NA
WP_157733583.1\|4047723_4047939_-	hypothetical protein	NA	NA	NA	NA
WP_094037246.1\|4048275_4048698_-	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_094036278.1\|4048796_4049249_-	hypothetical protein	NA	NA	NA	NA
WP_157733584.1\|4049796_4050096_+	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_094036280.1\|4050215_4050536_+	hypothetical protein	NA	NA	NA	NA
WP_094036281.1\|4050578_4051511_+	universal stress protein	NA	NA	NA	NA
WP_094037247.1\|4051525_4052032_+	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_094034448.1\|4052715_4053948_+\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	3.5e-21	26.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP022541

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

140 : 43355

Escherichia_phage(38.46%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094033518.1\|140_1391_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.0e-101	49.6
WP_094037307.1\|2528_3239_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	6.9e-22	36.6
WP_157733618.1\|4228_5989_-	hypothetical protein	NA	NA	NA	NA
WP_094037309.1\|6337_7048_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	5.0e-28	33.3
WP_094037310.1\|9347_9734_-	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_094037311.1\|9730_9955_-	transcriptional regulator/antitoxin MazE	NA	NA	NA	NA
WP_094037312.1\|10259_10979_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.0e-48	42.2
WP_094037313.1\|11065_11992_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A142IIG8	Enterobacteria_phage	1.5e-16	29.8
WP_094037314.1\|11997_12843_-	restriction endonuclease	NA	NA	NA	NA
WP_094037315.1\|12854_13862_-	replication initiator protein A	A0A0K1LLD0	Rhodobacter_phage	3.1e-68	41.1
WP_094037312.1\|14178_14898_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.0e-48	42.2
WP_094033518.1\|15210_16461_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.0e-101	49.6
WP_094037316.1\|17532_19101_-	ribulokinase	NA	NA	NA	NA
WP_094037317.1\|19104_19794_-	L-ribulose-5-phosphate 4-epimerase AraD	NA	NA	NA	NA
WP_094037318.1\|19881_20826_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094037319.1\|20877_21864_-	ribose ABC transporter permease	NA	NA	NA	NA
WP_094037320.1\|21889_23401_-	sugar ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.4e-08	26.2
WP_094037321.1\|23397_24180_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	5.7e-17	29.6
WP_094037322.1\|25092_26256_-	mandelate racemase/muconate lactonizing enzyme family protein	NA	NA	NA	NA
WP_094037323.1\|26438_27365_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_094037324.1\|27350_28250_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_094037325.1\|28566_29637_+	tartrate dehydrogenase	NA	NA	NA	NA
WP_094037326.1\|29650_30724_+	tartrate dehydrogenase	NA	NA	NA	NA
WP_094037327.1\|30970_33094_+	TRAP transporter fused permease subunit	NA	NA	NA	NA
WP_094037328.1\|33140_34109_+	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_157733619.1\|34227_35649_+	amidohydrolase family protein	NA	NA	NA	NA
WP_094037330.1\|35645_36458_+	alpha/beta fold hydrolase	Q3I8Y5	Monkeypox_virus	3.0e-05	27.7
WP_094037587.1\|37099_37933_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_157733650.1\|37938_38694_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.8e-29	42.7
WP_094037332.1\|38727_39591_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094037333.1\|39603_40374_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_157733620.1\|40397_41135_+	membrane biogenesis protein	NA	NA	NA	NA
WP_094037335.1\|41131_41614_+	hypothetical protein	NA	NA	NA	NA
WP_094037336.1\|41610_42543_+	carbohydrate kinase family protein	NA	NA	NA	NA
WP_094037312.1\|42635_43355_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.0e-48	42.2

DBSCAN-SWA_2

79896 : 126399

Planktothrix_phage(50.0%)

transposase,integrase

attL 69026:69085|attR 113136:114975

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
69026:69085	attL	NA	NA	NA	NA
WP_094034167.1\|79896_80925_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_094037364.1\|82048_83638_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094037365.1\|83849_84875_+	ABC transporter permease	NA	NA	NA	NA
WP_094037366.1\|84871_85777_+	ABC transporter permease	NA	NA	NA	NA
WP_094037367.1\|85776_86610_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_094037368.1\|86606_87368_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.3e-21	32.0
WP_094037369.1\|88492_89383_-	polysaccharide deacetylase	NA	NA	NA	NA
WP_094037370.1\|89379_90117_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-28	36.2
WP_094037371.1\|90082_90781_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_094037372.1\|90780_91458_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_094037373.1\|91527_92334_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_094037374.1\|92625_94092_+	aldo/keto reductase	NA	NA	NA	NA
WP_094037375.1\|94052_94868_-	ABC transporter permease	NA	NA	NA	NA
WP_094037376.1\|94864_95710_-	ABC transporter permease	NA	NA	NA	NA
WP_094037377.1\|95706_96780_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.5e-23	33.8
WP_094037378.1\|96742_97921_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_094037588.1\|98001_99303_-	glutamine synthetase	NA	NA	NA	NA
WP_094037379.1\|99376_100111_+	hypothetical protein	NA	NA	NA	NA
WP_094037589.1\|100122_100779_+	cysteine hydrolase	NA	NA	NA	NA
WP_094033142.1\|101974_103054_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_157733626.1\|103304_103874_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q716C2	Shigella_phage	3.3e-14	31.1
WP_094037381.1\|103854_104217_-\|transposase	transposase	NA	NA	NA	NA
WP_094037382.1\|105788_106949_-	hypothetical protein	NA	NA	NA	NA
WP_094037383.1\|107042_108215_-	YHYH protein	NA	NA	NA	NA
WP_094037384.1\|108259_109777_-	hypothetical protein	NA	NA	NA	NA
WP_094037385.1\|109849_110254_-	hypothetical protein	NA	NA	NA	NA
WP_094037386.1\|110404_111082_-	response regulator	NA	NA	NA	NA
WP_157733627.1\|111078_112557_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	8.2e-25	28.1
WP_094037388.1\|112911_113178_+	hypothetical protein	NA	NA	NA	NA
WP_094037389.1\|116337_117411_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
113136:114975	attR	NA	NA	NA	NA
WP_094037390.1\|117407_118316_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_094037391.1\|118349_119573_-	O-antigen ligase family protein	NA	NA	NA	NA
WP_157733628.1\|119698_120487_+	hypothetical protein	NA	NA	NA	NA
WP_094037393.1\|120483_122019_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_094037394.1\|123875_124568_-\|transposase	IS6 family transposase	NA	NA	NA	NA
WP_094037395.1\|125406_126399_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	3.0e-23	28.8

DBSCAN-SWA_3

273546 : 304788

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157733641.1\|273546_274188_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_094034181.1\|274650_275883_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	7.8e-13	28.6
WP_157733642.1\|278670_278934_-	hypothetical protein	NA	NA	NA	NA
WP_157733643.1\|279464_279608_+	hypothetical protein	NA	NA	NA	NA
WP_094037521.1\|280868_282236_-	copper oxidase	NA	NA	NA	NA
WP_094037522.1\|282232_283636_-	TolC family protein	NA	NA	NA	NA
WP_094037523.1\|283632_283848_-	hypothetical protein	NA	NA	NA	NA
WP_094037524.1\|283909_284245_-	hypothetical protein	NA	NA	NA	NA
WP_094037607.1\|284694_285498_-	DUF305 domain-containing protein	NA	NA	NA	NA
WP_094037525.1\|285715_286297_+	L,D-transpeptidase	NA	NA	NA	NA
WP_094037526.1\|287579_288539_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	7.7e-16	32.7
WP_094037527.1\|288970_289678_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_094037528.1\|289674_290205_-	hypothetical protein	NA	NA	NA	NA
WP_094037529.1\|290201_290621_-	hypothetical protein	NA	NA	NA	NA
WP_094037530.1\|290777_291329_+	hypothetical protein	NA	NA	NA	NA
WP_157733644.1\|291847_292222_+	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_157733645.1\|293363_293990_-\|transposase	transposase	NA	NA	NA	NA
WP_094037532.1\|294450_294930_+	hypothetical protein	NA	NA	NA	NA
WP_094037533.1\|296097_298224_+	AAA family ATPase	Q677Q6	Lymphocystis_disease_virus	1.0e-12	29.6
WP_094037534.1\|298718_300398_-	DUF927 domain-containing protein	NA	NA	NA	NA
WP_094037609.1\|301069_302254_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	1.5e-77	42.2
WP_157733646.1\|302607_302793_+	hypothetical protein	NA	NA	NA	NA
WP_094037535.1\|302913_304041_+	Fic family protein	D7RWK9	Brochothrix_phage	1.1e-05	24.2
WP_094037536.1\|304077_304788_-\|transposase	IS6 family transposase	A0A1X9I6E7	Streptococcus_phage	3.9e-25	38.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP022543

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

18121 : 67930

Escherichia_phage(27.27%)

transposase,integrase

attL 19454:19474|attR 60812:60832

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094037751.1\|18121_18832_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	3.0e-25	36.9
WP_094037752.1\|18860_19445_-	hypothetical protein	NA	NA	NA	NA
19454:19474	attL	NA	NA	NA	NA
WP_094037753.1\|19502_20213_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	3.0e-25	36.9
WP_094037754.1\|21079_22135_+	Hint domain-containing protein	NA	NA	NA	NA
WP_094037755.1\|22701_23652_+	Hint domain-containing protein	NA	NA	NA	NA
WP_094037756.1\|24615_25530_-	isocitrate lyase/PEP mutase family protein	NA	NA	NA	NA
WP_094037757.1\|25526_26198_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_094037758.1\|26331_29064_+	aconitate hydratase AcnA	NA	NA	NA	NA
WP_094037759.1\|29060_29477_+	hypothetical protein	NA	NA	NA	NA
WP_094037760.1\|29473_30835_+	dihydroorotase family protein	NA	NA	NA	NA
WP_094037761.1\|30860_31574_+	isochorismatase family protein	NA	NA	NA	NA
WP_094037762.1\|31596_32373_-	SDR family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	3.1e-07	24.8
WP_094037763.1\|32356_33154_-	ABC transporter permease	NA	NA	NA	NA
WP_094037764.1\|33153_34074_-	ABC transporter permease	NA	NA	NA	NA
WP_094037765.1\|34167_35196_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_094037766.1\|35195_36293_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.2e-26	37.2
WP_157733670.1\|36643_37684_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_094037768.1\|37680_38388_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_094037769.1\|38772_39804_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_094037770.1\|39845_40628_-	ABC transporter permease	NA	NA	NA	NA
WP_094037771.1\|40629_41526_-	ABC transporter permease	NA	NA	NA	NA
WP_094037772.1\|41566_42688_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.6e-28	34.5
WP_094037773.1\|43042_44431_+	hypothetical protein	NA	NA	NA	NA
WP_094037774.1\|44427_45846_+	hypothetical protein	NA	NA	NA	NA
WP_094037775.1\|45849_46080_+	hypothetical protein	NA	NA	NA	NA
WP_094037776.1\|46076_47147_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_094037777.1\|47143_47995_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_094037778.1\|48042_48240_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_094037779.1\|48264_48861_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.6e-14	26.9
WP_094037780.1\|48863_49748_-	DUF1403 family protein	NA	NA	NA	NA
WP_094037781.1\|49873_50971_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_094037782.1\|50977_51313_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_094037783.1\|51309_51555_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_094037784.1\|51610_52891_-	replication protein C	L7TKN6	Rhizobium_phage	3.5e-16	26.7
WP_094037785.1\|53117_54140_-	replication protein	NA	NA	NA	NA
WP_094037786.1\|54136_55435_-	AAA family ATPase	A0A240F4U1	Ochrobactrum_phage	2.9e-18	25.9
WP_094037796.1\|56672_57014_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_094037787.1\|57010_57304_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_094037788.1\|58354_58795_+	hypothetical protein	NA	NA	NA	NA
WP_157733671.1\|58824_59871_-	hypothetical protein	NA	NA	NA	NA
WP_094037751.1\|60068_60779_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	3.0e-25	36.9
WP_094037789.1\|61048_63928_+	Hsp70 family protein	M1NN56	Moumouvirus	1.0e-10	23.1
60812:60832	attR	NA	NA	NA	NA
WP_094037790.1\|63931_65095_+	AAA family ATPase	NA	NA	NA	NA
WP_094037791.1\|65109_66480_+	hypothetical protein	NA	NA	NA	NA
WP_094033518.1\|66679_67930_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.0e-101	49.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022540

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP022541

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP022543

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection