CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP016353	Prauserella marina strain DSM 45268 chromosome, complete genome	12 crisprs	csa3,WYL,DEDDh,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,cas4,DinG,casR	0	45	0	0

1. NZ_CP016353

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016353_1

• CRISPR_ID: NZ_CP016353_1
• CRISPR_location: 1027170-1027328
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP016353_1

Consensus_repeat	Method
CGAAGCAAGGGAGCTTTGCTATCAAATGCG	PILER-CR

spacers of NZ_CP016353_1

>1.1|1027208|49|NZ_CP016353|PILER-CR
CCGTTTCGACTCGCCGGGCCCGAGTGCCCCGGGTCCGTGCGCCGGAAAT
>1.2|1027295|21|NZ_CP016353|PILER-CR
CCCACGAACGACGTTCGGTTC

CRISPR arrays and Neighbor proteins around NZ_CP016353_1

CRISPR arrays

The CRISPR arrays of NZ_CP016353_1

>merge|NZ_CP016353|1|1027170-1027328|PILER-CR
CGAAGCAAGGGAGCTTTGCTGCCGTTTCGACTCGCCGGGCCCGAGTGCCCCGGGTCCGTGCGCCGGAAATCGAAGCAAGGGAGCTTTGCTATCACTTGCCCCGCCGAGCCCACGAACGACGTTCGGTTCGAAAGCAAGGGAGCTTTGCTATCGAATGCG

>NZ_CP016353|1|1|1027170-1027328|PILER-CR
CGAAGCAAGGGAGCTTTGCTGCCGTTTCGACTCGCCGG	GCCCGAGTGCCCCGGGTCCGTGCGCCGGAAATCGAAGCAAGGGAGCTTT
GCTATCACTTGCCCCGCCGAGCCCACGAACGACGTTCG	GTTCGAAAGCAAGGGAGCTTT
GCTATCGAATGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091810846.1|1032322_1033897_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|312032
NZ_CP016353.1|WP_091810856.1|1019017_1019830_+|cobalamin-binding-protein	unknown	unknown	gnl|CDD|238564
NZ_CP016353.1|WP_091810845.1|1033906_1034608_-|LppX_LprAFG-lipoprotein	unknown	unknown	gnl|CDD|319988
NZ_CP016353.1|WP_091810850.1|1026017_1026602_+|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_CP016353.1|WP_091810851.1|1025287_1025983_+|DUF998-domain-containing-protein	unknown	unknown	gnl|CDD|377627
NZ_CP016353.1|WP_091810870.1|1029901_1032226_-|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl|CDD|237060
NZ_CP016353.1|WP_091810802.1|1044031_1044781_+|type-1-glutamine-amidotransferase	unknown	unknown	gnl|CDD|153212
NZ_CP016353.1|WP_176879942.1|1035754_1037020_+|MFS-transporter	unknown	unknown	gnl|CDD|340913
NZ_CP016353.1|WP_091810857.1|1017618_1019031_+|RNB-domain-containing-ribonuclease	unknown	unknown	gnl|CDD|223631
NZ_CP016353.1|WP_091810792.1|1044897_1047870_+|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	unknown	unknown	gnl|CDD|237613
NZ_CP016353.1|WP_091810858.1|1016555_1017506_-|ATP-binding-protein	unknown	unknown	gnl|CDD|349754
NZ_CP016353.1|WP_091810855.1|1019801_1021229_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143465
NZ_CP016353.1|WP_091810849.1|1026568_1027108_-|MGMT-family-protein	unknown	unknown	gnl|CDD|376440
NZ_CP016353.1|WP_091810847.1|1028015_1029740_-|NAD+-synthase	unknown	unknown	gnl|CDD|237577
NZ_CP016353.1|WP_091810853.1|1022633_1024091_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|377939
NZ_CP016353.1|WP_091810852.1|1024213_1025101_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234723
NZ_CP016353.1|WP_091810844.1|1034676_1035642_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|181818
NZ_CP016353.1|WP_091810848.1|1027465_1027909_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP016353.1|WP_170140342.1|1021225_1022557_-|4-aminobutyrate--2-oxoglutarate-transaminase	unknown	unknown	gnl|CDD|235685
NZ_CP016353.1|WP_091810843.1|1037048_1038392_+|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl|CDD|223252

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091810846.1|1032322_1033897_+|alpha/beta-hydrolase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	9.9374e-22
NZ_CP016353.1|WP_091810856.1|1019017_1019830_+|cobalamin-binding-protein	gnl|CDD|238564	cd01144, BtuF, Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	2.13174e-34
NZ_CP016353.1|WP_091810845.1|1033906_1034608_-|LppX_LprAFG-lipoprotein	gnl|CDD|319988	cd16334, LppX-like, family includes lipoproteins LppX, LprA, LprF and LprG from Mycobacterium tuberculosis. This family includes the homologous lipoproteins LppX, LprA, LprF and LprG from Mycobacterium tuberculosis (Mtb), all of which share a core fold with lipoprotein transporter proteins LolA and LolB. Mtb contains components such as glycolipids, lipoglycans and lipoproteins that play critical roles in regulating host responses and promoting survival of the pathogen. Mtb LprA is a lipoprotein agonist of Toll-like receptor 2 (TLR2) that regulates innate immunity and APC function. LprF, which is also found in Mycobacterium bovis but not in the nonpathogenic Mycobacterium smegmatis, has a central hydrophobic cavity that binds a diacylated glycolipid that it transfers from the plasma membrane to the cell wall, which might be related to the pathogenesis of the bacteria. Similarly, LprG functions as a carrier of glycolipids and lipoglycans, such as lipoarabinomannan (LAM), during their trafficking and delivery to the mycobacterial cell wall, contributing to virulence; LAM inhibits fusion of phagosomes with lysosomes as a means for mycobacteria to evade host defense. In addition, LprG has potent TLR2 agonist activity that modulates antigen processing of dendritic cells and macrophages. LppX is required for the translocation of the key virulence factors, the phthiocerol dimycocerosates (PDIMs), to the surface of Mtb.	6.91469e-57
NZ_CP016353.1|WP_091810850.1|1026017_1026602_+|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	6.76967e-44
NZ_CP016353.1|WP_091810851.1|1025287_1025983_+|DUF998-domain-containing-protein	gnl|CDD|377627	pfam06197, DUF998, Protein of unknown function (DUF998). Family of conserved archaeal proteins.	0.000212692
NZ_CP016353.1|WP_091810870.1|1029901_1032226_-|accessory-Sec-system-translocase-SecA2	gnl|CDD|237060	PRK12326, PRK12326, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP016353.1|WP_091810802.1|1044031_1044781_+|type-1-glutamine-amidotransferase	gnl|CDD|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	3.58502e-57
NZ_CP016353.1|WP_176879942.1|1035754_1037020_+|MFS-transporter	gnl|CDD|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.3732e-96
NZ_CP016353.1|WP_091810857.1|1017618_1019031_+|RNB-domain-containing-ribonuclease	gnl|CDD|223631	COG0557, VacB, Exoribonuclease R [Transcription].	1.82491e-89
NZ_CP016353.1|WP_091810792.1|1044897_1047870_+|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase	gnl|CDD|237613	PRK14109, PRK14109, bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase.	0
NZ_CP016353.1|WP_091810858.1|1016555_1017506_-|ATP-binding-protein	gnl|CDD|349754	cd02034, CooC1, accessory protein CooC1. The accessory protein CooC1, a nickel-binding ATPase, participates in the incorporation of nickel into the complex active site ([Ni-4Fe-4S]) cluster of Ni,Fe-dependent carbon monoxide dehydrogenase (CODH). CODH from Rhodospirillum rubrum catalyzes the reversible oxidation of CO to CO2. CODH contains a nickel-iron-sulfur cluster (C-center) and an iron-sulfur cluster (B-center). CO oxidation occurs at the C-center. Three accessory proteins encoded by cooCTJ genes are involved in nickel incorporation into a nickel site. CooC functions as a nickel insertase that mobilizes nickel to apoCODH using energy released from ATP hydrolysis. CooC is a homodimer and has NTPase activities. Mutation at the P-loop abolishs its function.	5.89937e-30
NZ_CP016353.1|WP_091810855.1|1019801_1021229_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143465	cd07147, ALDH_F21_RNP123, Aldehyde dehydrogenase family 21A1-like. Aldehyde dehydrogenase ALDH21A1 (gene name RNP123) was first described in the moss Tortula ruralis and is believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and ALDH21A1 expression represents a unique stress tolerance mechanism. So far, of plants, only the bryophyte sequence has been observed, but similar protein sequences from bacteria and archaea are also present in this CD.	0
NZ_CP016353.1|WP_091810849.1|1026568_1027108_-|MGMT-family-protein	gnl|CDD|376440	pfam01035, DNA_binding_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain. This domain is a 3 helical bundle.	4.95135e-40
NZ_CP016353.1|WP_091810847.1|1028015_1029740_-|NAD+-synthase	gnl|CDD|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0
NZ_CP016353.1|WP_091810853.1|1022633_1024091_+|PucR-family-transcriptional-regulator	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	2.42479e-31
NZ_CP016353.1|WP_091810852.1|1024213_1025101_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl|CDD|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	3.20006e-164
NZ_CP016353.1|WP_091810844.1|1034676_1035642_-|helix-turn-helix-domain-containing-protein	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	3.6258e-110
NZ_CP016353.1|WP_091810848.1|1027465_1027909_-|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	9.12937e-09
NZ_CP016353.1|WP_170140342.1|1021225_1022557_-|4-aminobutyrate--2-oxoglutarate-transaminase	gnl|CDD|235685	PRK06058, PRK06058, 4-aminobutyrate--2-oxoglutarate transaminase.	0
NZ_CP016353.1|WP_091810843.1|1037048_1038392_+|type-I-glutamate--ammonia-ligase	gnl|CDD|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	0

Protein sequences

>NZ_CP016353.1|WP_091810849.1|1026568_1027108_-|MGMT-family-protein
MDEGFAVFETVFGYCALVWCGEVVVGSQLPEATADRAREAVHARFPGAGEQPPPGKIQQAILGVTALLRGERTDLSGVPLALDRVPPFHRRVYEVTLAIPAGSTMTYGQVATELGDPGSARAVGQALGNNPFAPIVPCHRVLAAGGKAGGFSATGGLDTKRRLLDAEGYHLEEPTLFDL
>NZ_CP016353.1|WP_091810850.1|1026017_1026602_+|DinB-family-protein
MPGMIGPVADERDGLLGYLAQQRYVLCLAAYGLTDEQARMRPTASALCVGGLIKHVAATELAWMNVVLGNPVDDTGTADFRFGHDETLADVIGEYERVATGTEEIVEGIADLGMAVRVPSEVPWFPDDVAAWSVRWVLLHLIEETARHAGHADILRESIDGATAFPLMAAAEGWPETPWLKPWRHRSNNVGSSR
>NZ_CP016353.1|WP_091810851.1|1025287_1025983_+|DUF998-domain-containing-protein
MPPVTHHRPTTLHTVHTLAVALLTIGGVGYLGWLLEFFLETGLSPLSASIDELSAVGQPYRNVFRTAEIIAGAAFVLSVPPLLRLAPVHWQARLTVGAVSVLGVLLVVRGVTAPDCALSSGPVCAQRQEFSAGHHVHHVASVLLSLHYAVGTGTLVLWWHGRWRVRAAVVAGLAALAWLAIIAVEWIVPGSYTGVAVRARAILVGVAIAVGIGYLLTVGKRQGGEWQDSRQ
>NZ_CP016353.1|WP_091810852.1|1024213_1025101_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MSSKSTSEHDHTGETTAPYGSGPSPQASTPRKKVRIHHLRELKDRGEPWPMLTAYDMYTAALFDEAGIPVLLVGDSAANNVFGYDTSLPVTVDELLPLVRAVTRSVSRALVVADLPFGSYQLSPEQALATAVRFMKEGRAQAVKLEGGQHFAAHVEALTSAGVPVMGHIGFTPQSEHNLGGYRVQGRGEAGEQLLADAIALQEAGAFAVVMEMVPAEVAKRVTHELRIPTIGIGAGSDCDAQVLVWQDMAGLRTGKAPRFVKRYADLAGALSGAARAFADEVRRGEFPAPEHAFH
>NZ_CP016353.1|WP_091810853.1|1022633_1024091_+|PucR-family-transcriptional-regulator
MALTLEALVAQRSLGLRVLAGRAELGREIAWVHPTELADPTVFLDGGELLLTTGLTSGAEPAGDYVRRLAAAGVTGLGFGVGLSHDAVPPGLVAAAEAAAFPLLEVPPPTPFIAITKAVSSALAEERYAEVVRTGKGQQELTRTALRHRAPGALARKLARLVDGWVLLLDGGGSVREAAPASARAMATAVNAELGTGKAGTGLVSIAGDEVVVQALGTRASGFLVAGTSTTFGAAGRHLIATAAALLSLAMEQDRARGTTLRGLRTGLFELLLAGQDELALTVLRSAFGTNPDPPWTLTVLTGPAKDRAAAADVLETVADEDQSVFFAEHSSVLVVLTGERSGQAFIERIAGLHAGVSPSTTDVATGFRQARQAADAAMVAGKPLLHFTEHAGNGVLGLLGSDTAVAFADAVLGPLREHDAEGRGALADSLRCWLEHNGHWDTSAARLGIHRHTLRNRMAKTARILGRDLDSPGVRAELWLALNV
>NZ_CP016353.1|WP_170140342.1|1021225_1022557_-|4-aminobutyrate--2-oxoglutarate-transaminase
MTATTHRRLRTEIPGPNSLALHQRRTDAVAAGLTSTLPVYITSAEGGLLTDADGNTLIDLGSGIAVTNVGHAAPAVVDGVREQAGLFTHTCFMVTPYEGYVRVCEELAALTPGDHAKRSVLFNSGAEAVENAVKIARTATGRQAVVVFDHAYHGRTNLTMALTAKSLPYKHGFGPFAPEVYRVAGSYPFRDAEGRTGEQAAAEAIDRVEKQIGADAVAAVVVEPIQGEGGFIEPAPGFLPALSRWCAANGVVFVADEVQTGFCRTGEWFACDHEGVVPDLIATAKGIAGGLPLAAVTGKAELLDSVHAGGLGGTYGGNPVSCAAALGAIETMREGDLAGAAKRIGETAIASLRELAATTGAIGDVRGRGAMIAIEFVKPGTTEPDAAITSRIAAACHAAGVVVLTCGTYGNVVRLLPPLTLPPELLREGLDVLEDAIREETSR
>NZ_CP016353.1|WP_091810855.1|1019801_1021229_-|aldehyde-dehydrogenase-family-protein
MSTPFWIAGSPVKSGDTAVVRHPYDGGEAGGHYVPTARDIEQAVAAAHDARAETAAAPAHVRADALDHVARAITERAEEFASLITSESGKPLKWARAEVGRAASTFRWSAEETRRFAGELQRLDTDAGSRGRLALVRRVPRGPVLGITPFNFPLNLVAHKVAPAIAVGAPIVLKPAPATPLTALLLGEVLAETQLPEGSWSVLPVGNEHAAALAADPRLPVVSFTGSVPVGWGIRDAVPRKHVTLELGGNASVVVCPDWTDLDMAADRIATFAMYQAGQSCVSVQRVYAHSHVYEELTEKVLAKVAALGTGDPRSPHTDVGPLINTAAAERVESWVADAVSEGASLRLGGERDGATVRPTVLTHAPEHVSVMADEVFGPVVSVNPVDSVEDAFSLVNASRFGLQAGVFTRDLPTAFAASATLEVGGVVVGDVPSYRADQMPYGGVKDSGVGREGPAAAMADLTEERVTVLTGLPL
>NZ_CP016353.1|WP_091810856.1|1019017_1019830_+|cobalamin-binding-protein
MSGPDKPLTDDLGEAVPLRGAPTRVVSLVPSLTEAVELTLPGIVAGATDYCTHPDALAAPRVGGSKYPDVDAVLELAPDLVLANAEENRKEDVERLRGQGVPVWVMAAPATVPSALRSLRALFTGILGTGAPDWLVTAEELWRESRSPAMTAVVPVWRKPWVVLGRDTFGGDVLRRLGVRHAYSADDERYPRPKIGELRELFAAGKADVLVLPDEPWEFTADDGPDAFPGVPYTLVSGRYLTWYGPSLVEAHQALSAALTTVTREVRSAR
>NZ_CP016353.1|WP_091810857.1|1017618_1019031_+|RNB-domain-containing-ribonuclease
MALVVHTPGAGDFASLRADFELPESFPPDVLAEAEAVAGDPEGAGEREDATGIPFVTVDPAGAKDLDQAVCLEPVRGGGIRVHYAIADLAAFVPPGGAIDAEARRRGQTLYLPDGNVPLHPPELSEGAASLLPGMVRPAVLWTIDTDSGGEPTAVRVRRALVRSTERFDYDTVAAALEAGTAHPSIAALPALGRARRELAVRRGAVELQLPEQEIGAGPDGGWLLVRRPRNDVEAWNAEVSLLTGMTAASIMLEAGVGVLRTLPEADDETVDWLRRSAGALGIPWPREATVSELLAGLDPAQPSSLALYAGTTRLLRGAGYTAFDGGVPELATHAGIGGPYAHVTAPIRRLVDRFATEVCLAVTSGKPVPRWVRASLAELPELMQGSDTFAARVERAYLDQVEAWILAEHIGRVFDAVVLRAEENKAEIFVENPPVLGKCSGSGFPEGGRISVRLTAVDVTKRKVSFVRA
>NZ_CP016353.1|WP_091810858.1|1016555_1017506_-|ATP-binding-protein
MKVAFVGKGGSGKTTLASLFTAYLVERRRPVLAIDADINQHLAVALGATEDEAAALPTLGDNLPLIKRYLCGDNPRITAPEAMIKTTPPGRGSTLVTPREENPITDACFRDVAGARLAVTGRFADDDLGVACYHSKVGAAELLLNHMIDGKDEYVVMDMTAGADAFASGLFTRFDVTFLVCEPTVRSVGVFRQYTDYARDFGIRLAVIGNKVNEADDVEFLHDQVGEHLLGWISGSRHVRAAERGAARPIGELERENLATLDTMLSTVDATERDWARYQRQAVEFHLRNANAWAGSELAEQVDPGFVLSPLAPALG
>NZ_CP016353.1|WP_091810848.1|1027465_1027909_-|nuclear-transport-factor-2-family-protein
MSIAAPVNTRTVVEELLRRIGEGDPERIAELYAEQGDWKLDWPEAEHGRTATPWIRHRSTRADAAAHYRELAEYHVPERVATEVERILVDGSDAVVLGEIRQTARPTGRAYHARFALHLTIEDGLVTRHHIYEDSLAVAQAFEAENR
>NZ_CP016353.1|WP_091810847.1|1028015_1029740_-|NAD+-synthase
MPQLRIALAQINPTVGDLTGNAELIVTRAREAVASGAHVVVFPEMSLTGYPVEDLALRKTFADASHAEVDALATRLAEAGCGELLTYVGYLDQDDAGPRNAVAALLGGRVVASQYKHHLPNYGVFDERRNFKPGDALEVLRFHGLDIGMVICEDLWQDGGPVAALGEATVDLVVSPNASPYERSKDDVRLPLVAGRAVEAGAPVVYTNLVGGQDDLVFDGDSIVVAADGHLLARAPQFVEHLLVLDLDLPRGAGTREGRFAGIEVSHRVLSAEPLPHYEPLPEPTISEPLPDEAEVWSALVVGLRDYARKNGFRSVIFGFSGGIDSAVTAALAVDALGPEAVHGVSMPSAYSSEHSRADAADLARRLSCPFRVEPVDRMVAQYVDQLGLAGTGLAEENIQARARGMLLMALSNLEGHLVLATGNKTEIAVGYSTIYGDAVGGFAPIKDVFKTHVWALAKWRNAEAEKRGETPPIPENSITKPPSAELRPGQLDSDSLPDYPLLDDVLDDYVEGDRGYKALQEAGFDAETIDRVVRMVDKAEFKRRQYPPGTKITFKAFGRDRRLPITNAWREAH
>NZ_CP016353.1|WP_091810870.1|1029901_1032226_-|accessory-Sec-system-translocase-SecA2
MALMGRVGKRLRRIIQRPASVELTRYEALLPTIEKREPGLEELSDAELTEAANKLREAENFGDEQIAELCALGREAARRALGERAFDVQLLGVMGLLSGNVVQMATGEGKTLAGALAAAGYALQGKRVHVISVNDYLARRDAEWMRPVYELLGVSVGWVEPVLTAEQRRAAYAAEVCYGAVSEIGFDVLRDRLVTDVEKLAQPEPEVAIIDEADSVLVDEARVPLVMAGSVDAGVADEEVANIVRRLRVGLHYETDPDGRNAWLTSAGASVVEKALGGIELYEEEGSDRLAAVNVALHAHALLTRDVDYLVREGKVQLINASRGRVAELQRWPDGLQAAVEAKEQLPPSDHGEILDSITVQALIARYPQVAGMTGTAVAVAEQLREFYKLEVAAIPQNTPNVRKDEPHRIFASPGHKLRAIVEEIRTVHEDGQPILVGTQDVAESEELAEKLAKAGLPCVVLNARNDAEEAAIIAEAGKFDAITVSTQMAGRGTDIRLGGADGADRERVAELGGLHVIGTARYPSSRLDDQLRGRAGRQGDPGSSVFFASLNDELVLSNAPDVPEGIEADDKTGEVTDSAAHRQINHAQRVAEGVDLEIHRNTWRYTRLIEHQRAELLKHRDEVLRTEAARERLEEAEPDRYKELAEKLDEETLTRICRDIELYHLDQLWADHLAFLTDVRETIHLRALAKETPLDEFHRAAIPEFHKLRGEAEKRSAKTLVEAEIAEGSVDLAAAGIRRPTSTWTYLVQDNPFDSDAEQALKKVRGLLRKKRN
>NZ_CP016353.1|WP_091810846.1|1032322_1033897_+|alpha/beta-hydrolase
MSARERYLSLAACLLVVTGLTACSSEPTDPPSRSGPAGPVPDGLDTYYSQQLDWGACAPFATSETASRMFQADGIECARMTVPLDYEKPEGTTIEIGVLRHKSADDADRIGSLVLNPGGPGASGMVSAASIGRGVASQEVGEKFDVVGFDPRGVGASEPQVTCLTADERDEDRASDSEVDGSPEGVAAQEQQEKDFAAKCAQRTEHGDDMLAHLGTRDVVKDLDVLRSALGDEKLTYLGYSYGTRIGYTYAEAFPRNVRALVLDGALDPEQDLVESLVAQGEGFGKAFGEFASWCAERADCALGQDPAAATKAYQDLTRPLIDNPVDVGGRALSYEDATTGTIQALYTEQFWEQLDAGLAELANGQGQTLMSLADMYNERGSDGQYATTQDAFVAIRCVDDPRVTDKQEILEAQRRYAEVAPFLDPGTEYSSARDACTFWPVPNTSEPHLPKVDGVPPSLVISTTNDPATPYEAGVSLAKAMKGGLLTFEGTQHTVFLQGDTCVDEIGTRYLVDGELPEEGARC
>NZ_CP016353.1|WP_091810845.1|1033906_1034608_-|LppX_LprAFG-lipoprotein
MVSRRIAFLLVLVIGMLGGCTPSPDTSGPLPEGRGLVDESATQLRELRSVRFQVSLSGTVPGLSIREVDGVATRQGGEYGFASGDADVQEHTDRVQYRFLLSGDRLRLTDKDGNTSERPVPAEFSPARLLDPERGLYQLLEKASGLTTEGREELDGVSSYRVTGELSRSVVSALVPGIDADVDVKFWVAEGKNRDLLRLWIQIPPRQKNEGSVMLEVALSEHNAPVRESSDAS
>NZ_CP016353.1|WP_091810844.1|1034676_1035642_-|helix-turn-helix-domain-containing-protein
MHQVVVLAIDEVIGYDMQIPPQIFNTARLSGERLYNVRLCGIDDKPVRVATGYTAVLDHGPDVLAEADTVIIPGTKARGPRYEGTLPGAIADALALIPGSARIMSICTGAFVLGAAGLLDERPATTHWAHSRQFRELYPRVKLDEDVLFVDDGDVLTSAGLAAGVDLCLHVVRKDHGAEVANAAARYCVVPPWREGGQSQFIERPFVETWAGSTAPTRAWALQHLAEPLDVAALACHASMSTRTFARRFREETGLPPHAWLTKQRVAHARRLLESTELSVEQVAVQSGLGSAASLRQHLGAAIGVTPLAYRRTFAAQRGKV
>NZ_CP016353.1|WP_176879942.1|1035754_1037020_+|MFS-transporter
MHWAWLVAFAAFVALVGAAGFRAAPSVLIDPLHEEFGWSRGTISAAVSINLLLYGFISPFAAALMERFGMRKVVASALALVAAGSGFTVFMTESWQLLLCWGVLVGTGTGSMALAFVATVTGRWFVKHRGLVSGILTAAGAAGQLVFLPLVAMLATDQGWRTASLVVSGAALAVVPIVLLLLRDWPADVGTTAYGAPEGEQTPRATGGTMRAGGSAMRALTALRDAARTRTFWLLAGGFAICGASTNGLIGTHFVPAAHDHGMPHTTAAGLLALVGLFDVVGTIASGWLTDRVDPRWLLGTYYVLRGASLLVLPMLFAPTTEPPMWAFIVFYGLDWVATVPPTVALCRTWFGANGPIVFGWVFASHQVGAAVAALGAGLTRDQLGSYDLAWFAAGGLCAVAAVLSLSIRKSSPEGDPAPKH
>NZ_CP016353.1|WP_091810843.1|1037048_1038392_+|type-I-glutamate--ammonia-ligase
MDRQQEFVLRTLEERDIRFVRLWFTDVLGFLKSVAVAPAELEGAFSEGIGFDGSAIEGFARVYESDMVAKPDPSTFQVLPWETPDGGLYSARMFCDIAMPDGSPSWADPRHVLRRQLSKASEAGFTCYVHPEIEFFLLANLPEDGSEPEPADNGGYFDQASHATATHFRRHAIEALEAMGISVEFSHHEGAPGQQEIDLRYADALTMADNVMTFRYVVKEVALTQGVRATFMPKPFTGQPGSGMHTHVSLFEGDQNAFYSPEDPYELSETGKAFVAGLLTHAREISAVTNQWVNSYKRLIRGGEAPTTVSWGRANRSALVRVPMYSPGKASSRRVEIRTLDSACNPYLAYSVILAAGLKGIEKGYELPPAAEDNIWTLSDSERKAAGYPELPQNLGEALAEMEHSELLPDALGEHVYDFFLRNKRVEWDNYRSEVTPYELRTLLPML
>NZ_CP016353.1|WP_091810802.1|1044031_1044781_+|type-1-glutamine-amidotransferase
MPRLLVIQPDASDPVGPLGEWFAEAGAELDVRLPPIDALPADLAGYQGLVCLGGGMNAEDDTRYPWLADVRRLLREAVGANLPTLGVCLGAQLLTVATGGKVAPGQDGPEAGASLVAKKDAAWKDPLFADLPLMQDVLQFHQDVIDRLPVRAELLASSPRYPNQAYRYGRCGYALQFHIETTPDVVREWVKSAPDVAASASEGAFTDERLAEAHADIAETWQPFAERFVRLAAGDIEPATDQPHTLPLV
>NZ_CP016353.1|WP_091810792.1|1044897_1047870_+|bifunctional-[glutamine-synthetase]-adenylyltransferase/[glutamine-synthetase]-adenylyl-L-tyrosine-phosphorylase
MVERARPTASAARFGFTDERAAADLRMLGFWDEAGPVPGCEQILTAFSRAPDPDLALRAIDRIKTADETGWPELSRALRADPVLRAQLFAVLGTSGALADFLVNTPEEWRRLTAGSGTPSDEYTAELTQAMAHDGASLTGAAAEQALRKAYRGLLLEIAADDLAHTVDPALDQPSYAQTTGALTQLADAALRAGLGVAEQELRGPTGATLAVIAMGKCGGRELNYVSDVDVVFVGEGDLQIATRLAAAMMRIVGRACFEVDAALRPEGKAGALVRTLEGHEAYYQKWARTWEFQALLKARPVAGDVELGNRYTELVAPMVWSASARENFVTDVQQMRRRVERHVPADIADRELKLGRGGLRDVEFAVQLLQLVHGRVDTAIRSASTIEALEELGAGGYVGRADAVELRVSYEFLRTLEHRLQLRGLLRTHLFPEFDDSAQLRWLARASGVRPLRGKSEAAHLVAEYRRHVQRVRRLHEKLFYRPLLEAVARVPTAVLRLTTDQAKSRLHALGYAAPDGALQHIRSLTSGVSRRAAIQQALLPMLLDLLADTPDPDGGLLAYRRVSEALADTPWYLRVLRDEAAVVEQLAMLLGTSKLVPDLLVRAPEVLHMLGESERLTARTPEEVATSLRAAARRQPGLKAAVTAARSLRRHELLRVACADLLGLLDVPAVCGALSSVWAAVLQSALAASIRQKSADIGSEPARIAVIGMGRLGGAELGYGSDADVLFVCERANGASDSEALKFATSVAETVRQVLGAPSQDPALEVDANLRPEGRSGPLVRTFDSYLAYYSRWGEVWEAQALLRARFVAGDDDLGARFIAAIGRFRYPEGGLDPSRIREVRRIKARVETERLPRGADPTTHAKLGRGGLADVEWTVQLMQLRHAHEVPGLRTPSTLAALRATAEARLADEAEINSLTEAWLLATRARNVAMLVRGKPVDQLPTSGRELAAAARIFGYSADDDPGEFLDSYRRTTRRAHAVVERLFYES

Crispr_ID: NZ_CP016353_2

• CRISPR_ID: NZ_CP016353_2
• CRISPR_location: 1413175-1413315
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP016353_2

Consensus_repeat	Method
ACCGCCACCAAGGCGGCTCCGAAG	CRISPRCasFinder

spacers of NZ_CP016353_2

>2.1|1413199|36|NZ_CP016353|CRISPRCasFinder
ACGGCGTCGAGGACCGCGGCCAAGACCACAGCCAAG
>2.2|1413259|33|NZ_CP016353|CRISPRCasFinder
TCGACTGCGAAGGCGACGACCGCGAAGGCGTCG

CRISPR arrays and Neighbor proteins around NZ_CP016353_2

CRISPR arrays

The CRISPR arrays of NZ_CP016353_2

>merge|NZ_CP016353|2|1413175-1413315|CRISPRCasFinder
ACCGCCACCAAGGCGGCTCCGAAGACGGCGTCGAGGACCGCGGCCAAGACCACAGCCAAGACCGCCACCAAGGCGGCACCGAAGTCGACTGCGAAGGCGACGACCGCGAAGGCGTCGACCGCGAAGAAGACGACGGCGAAG

>NZ_CP016353|2|1|1413175-1413315|CRISPRCasFinder
ACCGCCACCAAGGCGGCTCCGAAG	ACGGCGTCGAGGACCGCGGCCAAGACCACAGCCAAG
ACCGCCACCAAGGCGGCACCGAAG	TCGACTGCGAAGGCGACGACCGCGAAGGCGTCG
ACCGCGAAGAAGACGACGGCGAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091800793.1|1419669_1420170_+|cysteine-dioxygenase-family-protein	unknown	unknown	gnl|CDD|380416
NZ_CP016353.1|WP_091799747.1|1411911_1412514_+|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl|CDD|179314
NZ_CP016353.1|WP_176879593.1|1414556_1416800_-|RNA-degradosome-polyphosphate-kinase	unknown	unknown	gnl|CDD|235469
NZ_CP016353.1|WP_091799714.1|1406005_1407487_+|glutamate--tRNA-ligase	unknown	unknown	gnl|CDD|234953
NZ_CP016353.1|WP_091800779.1|1402607_1403648_+|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl|CDD|179579
NZ_CP016353.1|WP_091799755.1|1416867_1417551_-|2-phospho-L-lactate-guanylyltransferase	unknown	unknown	gnl|CDD|274643
NZ_CP016353.1|WP_091799770.1|1423468_1424041_-|DUF3515-domain-containing-protein	unknown	unknown	gnl|CDD|378794
NZ_CP016353.1|WP_091799764.1|1420905_1422288_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NZ_CP016353.1|WP_091800789.1|1417626_1418385_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_CP016353.1|WP_091799712.1|1403875_1404646_+|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NZ_CP016353.1|WP_091799706.1|1397439_1399038_+|phosphoglycerate-dehydrogenase	unknown	unknown	gnl|CDD|237436
NZ_CP016353.1|WP_091799733.1|1407573_1408365_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223943
NZ_CP016353.1|WP_091800786.1|1413595_1414528_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239645
NZ_CP016353.1|WP_091800782.1|1404664_1405918_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235729
NZ_CP016353.1|WP_091799743.1|1410395_1411814_+|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl|CDD|235490
NZ_CP016353.1|WP_091799740.1|1409583_1410303_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP016353.1|WP_091799761.1|1420166_1420838_-|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|378988
NZ_CP016353.1|WP_091799709.1|1399115_1402433_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173800
NZ_CP016353.1|WP_091799758.1|1418386_1419397_+|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|234629
NZ_CP016353.1|WP_091799767.1|1422299_1423397_+|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234993

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091800793.1|1419669_1420170_+|cysteine-dioxygenase-family-protein	gnl|CDD|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.53752e-25
NZ_CP016353.1|WP_091799747.1|1411911_1412514_+|3-isopropylmalate-dehydratase-small-subunit	gnl|CDD|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	2.27528e-123
NZ_CP016353.1|WP_176879593.1|1414556_1416800_-|RNA-degradosome-polyphosphate-kinase	gnl|CDD|235469	PRK05443, PRK05443, polyphosphate kinase; Provisional.	0
NZ_CP016353.1|WP_091799714.1|1406005_1407487_+|glutamate--tRNA-ligase	gnl|CDD|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP016353.1|WP_091800779.1|1402607_1403648_+|3-isopropylmalate-dehydrogenase	gnl|CDD|179579	PRK03437, PRK03437, 3-isopropylmalate dehydrogenase; Provisional.	0
NZ_CP016353.1|WP_091799755.1|1416867_1417551_-|2-phospho-L-lactate-guanylyltransferase	gnl|CDD|274643	TIGR03552, F420_cofC, 2-phospho-L-lactate guanylyltransferase. Members of this protein family are the CofC enzyme of coenzyme F420 biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.02709e-28
NZ_CP016353.1|WP_091799770.1|1423468_1424041_-|DUF3515-domain-containing-protein	gnl|CDD|378794	pfam12028, DUF3515, Protein of unknown function (DUF3515). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 166 to 214 amino acids in length. This protein has a conserved RCG sequence motif.	2.28114e-43
NZ_CP016353.1|WP_091799764.1|1420905_1422288_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	2.34058e-104
NZ_CP016353.1|WP_091800789.1|1417626_1418385_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	3.60055e-44
NZ_CP016353.1|WP_091799712.1|1403875_1404646_+|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.21787e-99
NZ_CP016353.1|WP_091799706.1|1397439_1399038_+|phosphoglycerate-dehydrogenase	gnl|CDD|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NZ_CP016353.1|WP_091799733.1|1407573_1408365_+|HAD-family-hydrolase	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	1.44389e-36
NZ_CP016353.1|WP_091800786.1|1413595_1414528_-|NUDIX-hydrolase	gnl|CDD|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	6.06186e-40
NZ_CP016353.1|WP_091800782.1|1404664_1405918_-|FAD-dependent-oxidoreductase	gnl|CDD|235729	PRK06185, PRK06185, FAD-dependent oxidoreductase.	0
NZ_CP016353.1|WP_091799743.1|1410395_1411814_+|3-isopropylmalate-dehydratase-large-subunit	gnl|CDD|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_CP016353.1|WP_091799740.1|1409583_1410303_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.90315e-52
NZ_CP016353.1|WP_091799761.1|1420166_1420838_-|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	6.07611e-43
NZ_CP016353.1|WP_091799709.1|1399115_1402433_+|S8-family-serine-peptidase	gnl|CDD|173800	cd07474, Peptidases_S8_subtilisin_Vpr-like, Peptidase S8 family domain in Vpr-like proteins. The maturation of the peptide antibiotic (lantibiotic) subtilin in Bacillus subtilis ATCC 6633 includes posttranslational modifications of the propeptide and proteolytic cleavage of the leader peptide. Vpr was identified as one of the proteases, along with WprA, that are capable of processing subtilin. Asp, Ser, His triadPeptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	8.3466e-46
NZ_CP016353.1|WP_091799758.1|1418386_1419397_+|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl|CDD|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	5.34933e-163
NZ_CP016353.1|WP_091799767.1|1422299_1423397_+|D-alanine--D-alanine-ligase	gnl|CDD|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	7.24552e-179

Protein sequences

>NZ_CP016353.1|WP_091799747.1|1411911_1412514_+|3-isopropylmalate-dehydratase-small-subunit
MEPFTKHTGIGVPLRRSNVDTDQIIPAVYLKRVSRTGFEDGLFAAWRGDEHFVLNQEPFKAGSVLVAGPDFGTGSSREHAVWALMNYGFRVVISSRFADIFRGNSGKQGLLAAQCEQADVELLWKLLETEPGTEVTVDLAEKTVRAKDFVASFSIDDYTRWRLLEGLDDIALTLRHADEIASFESRRPSWKPLTIPSASS
>NZ_CP016353.1|WP_091799743.1|1410395_1411814_+|3-isopropylmalate-dehydratase-large-subunit
MAEERGRTLAEKVWDAHVVRRGEGAEPDLLYIDLHLVHEVTSPQAFDGLRLAGRPVRRPDLTIATEDHNVPTVDIELPIADPVSRTQVDTLRRNCKEFGVRLHPMGDIEQGIVHVIGPQLGLTQPGTTVVCGDSHTSTHGAFGAMAFGIGTSEVEHVLATQTLPLRPFKTMAVNVEGTLRPGVTAKDVILAVIARIGTGGGQGYVLEYRGSAISALSMESRMTICNMSIEAGARAGMIAPDETTFAFLKDRPHAPRGADWEAALAEWRELRTDDGAVFDAEVTIDADELTPYVTWGTNPGQGLPLGSSVPDPERIADENERTAAEKALSYMDLVPGTPLREIPVDTVFLGSCTNGRIEDLRVAAGVLEGRKVAEGVRMLVVPGSMRVRKAAEDEGLDTIFTAAGAEWRQAGCSMCLGMNPDQLKPGERSASTSNRNFEGRQGKGARTHLVSPLVAAATAVRGTLSSPEDLGQ
>NZ_CP016353.1|WP_091799740.1|1409583_1410303_-|IclR-family-transcriptional-regulator
MGQHNPENQQSGIGVLDKAVAVLHAVAEEPCGLAELCARTGLPRATAHRLAVGLEVHRLLRRGPDGRWRPGAALGELAGGTTDPLLDAASIILPKLRDITGESVQLYRRDGVQRVCVSTAEPPSGLRDTVPVGTRLSMTAGSGAKVLVAWADSHTQRTVLADAVYGERTLLEVRRRGWAQSVAEREPGVASVSAPVRDSSGTVIAAVSVSGPVERIGRKPGARWAADLLAAADALQERL
>NZ_CP016353.1|WP_091799733.1|1407573_1408365_+|HAD-family-hydrolase
MAFAFGSPTASQTVSDNAASPPWVPPELRLVCLDIDDTLIDFSAASRRSLAALIGRTDMWPLWERITDEHVARVVAGGLDYADMHVRRTEAFLTELGVIAAHPDIAEFEVQRKDRLRRYLRLFDDVLPCLDWLIAAGVRLAAVTNASGAHQREKLANLGLARFFDHVAIAGEMGVAKPDPVMFHSVCFKLGCDPAEAVHVGDKLGTDAIGARDAGLAGVWLDRDPSGSADIDPPAGIHVLAGLDELPELLVSEFVRVGVPAQR
>NZ_CP016353.1|WP_091799714.1|1406005_1407487_+|glutamate--tRNA-ligase
MTENKAVRARFCPSPTGTPHVGLIRTALFNWAFARHHGGSLVFRIEDTDAARDSAESYEALLEALRWLGLDWDEGPEVGGQYGPYRQSERGEVYSDVARKLLEAGELYEAYSTNEEVEQRRVAAGQDPKLGYDNFDRELTDEQRAAFVAEGRSPVLRLRMPDHDLTWNDLVRGEISFKAGTIPDPVLVRANGQPLYTLTNPVDDALMRITHVLRGEDLLPSTPRQLALYEALTRVGVAEFIPEFGHLPYVMGEGNKKLSKRDPTSNLFNYRDRGFIKEGLLNYLALLGWSIADDRDIFTVDELVEAFEITKVSANPARFDVKKAEAINGVHVRALDIGDFTERVLPYLVGGGVLPASPSAAQLETLRAIAPLVQERVTVLSEAVDLLRFLFADEESFAPEEAAATKNLGPVSEPVLRAAIEALEATGSWRAGEIEQALKNALVDGLGLKPRKAFAPIRVAVTGRTVSPPLYESMELLGREISLGRLRRALPRN
>NZ_CP016353.1|WP_091800782.1|1404664_1405918_-|FAD-dependent-oxidoreductase
MSEHPATTGKEATTCAIIGAGPAGMVLGLLLARAGVEVTVLEKHGDFLRDFRGDTVHPSTLRLLDELGLGEQFAALPQSKLEEIAFPDGDEGLVVVGDLRRLNVRHPYIAITPQWDLLNLLAEAAEKEPTFTLRRNTEVTGLIEQNGVVEGVRYRERQGGTGELRADLTVACDGRWSIARRQAGLRPKELPVPIDAWWFKLPQHEGEESASLTPTARDGRFAIVIPRSGYYQIAYIAKKGIDASLRARGIEHFREEVAAVRPELADRVDRLGSMDDVKHLDVRVNRLNRWHTEGLLCIGDAAHAMSPIGGVGINLAVQDAVATATVLAAPLRKGEVTSSRLAKVRRRRLLPTIAVQALQQLLHKGVAEPIVEGRRTGPPKPVIKLMRRFPKLSFIPAYLIGIGLRPEHAPAFARRVS
>NZ_CP016353.1|WP_091799712.1|1403875_1404646_+|fumarylacetoacetate-hydrolase-family-protein
MRLGRIAHPEGVAFVSVEGDGADAVVLEIADHPFGNPTFTGRRWPLADVRVLAPILPSKVVAVGRNYAAHAQEFGNEVPKEPMIFLKPSTSVIGPNVAIKRPRASSQVDFEGELAVVIGQPVRNVPAARAGAAILGYTVGNDVSARDLQRSDGQWGRAKGFDTFCPLGPWIETSLDASDLALRSEVDGEVKQDARTSALVHKIPELVEFVSGVMTLLPGDVILTGTPEGVGPVENGQQVSITIEGIGTLTNPVQDA
>NZ_CP016353.1|WP_091800779.1|1402607_1403648_+|3-isopropylmalate-dehydrogenase
MRLAVIPGDGIGPEVVTEALKVLTEVVPGAETTNYDLGATRWHSTGELLPESVLGELRQHDAILLGAVGDPSVPSGILERGLLLRLRFELDHHVNLRPARLYPGVRGPLADPGEIDMVVVREGTEGPYAGNGGLLRKDTEHEIATEVSVNTAFGIRRVVADAFQRAQERPRKHLTLVHKTNVLEHAGSLWSRIVEEESLEHPDVTVAYSHVDAATIHLVTDPSRFDVIVTDNLFGDIITDLAAAVTGGIGLAASGNLDITKRNPSMFEPVHGSAPDIAGQSLADPTAAALSVSLLLDHLGQKEAARRIEASVAFDLATRDQASPGSTQAIGDRLAALVSSNTRQAS
>NZ_CP016353.1|WP_091799709.1|1399115_1402433_+|S8-family-serine-peptidase
MSMNRWVARSVAAAMTVVLAGSVTGVASAQDEPPPARGLDPASVDPAKVAGKLSPRLAGAEGSTTAFVQLDRTPAVDAFNEVRPQGLEVAREAAVEARQVVEDTVDSVVGVLRTLDSNTTVLARTTNAVAGAIVTADAAALAGIAERDDVLSVRPVVPKTRTNTSAVQLTDTLTAWQQTGRFGDGVRIGIIDDGIDYTHADFGGPGTKEAYESIDPTVVEASYFPTAKVVGGTDLVGDEYDGSGSPAPDPNPLACGNHGTHVAGTAGGFGVEADGSTFTGDYASLTPERVDEMRIGPGTAPKAQLYAIKVFGCTGSTNVTAQAMDWALDPDGDGDFSDRLDLVNLSLGSDYGAPDDPDSLFVRKLAANNVLPVFSGGNGGDLYDIGGSPGNTPEALTVASTRDASILRDAVDVTAPPGTTGRYGGQYSQDYAGYDELDLTRAVVALSAGNADGCEPYSAEDAAAVADKFVWLEWDDDDATRACGSFARAQNAQDAGAAGALFSSTVEHFAAGLAGNEGIPVFQFTGSATEAVRSSLEAGTLEVRMSGAARASLHTEDQSIVDTPSVFTSRGVRGPSVKPDVAAPGDTIASAFAGSGNDRTVLSGTSMAAPHTSGVAALIRQAHPDWTVEEVKAAVVNTAGHDVSDDSGTFAPQRVGAGRLDAKAALDNSVLAYVKDDPGSVSVTFGTIEAAKRTSVTKTVKVVNKGTNVVDLGVGYEGVTQQPGVRYEVSKSSVRLSPRGVATVGVTVHVDPSALRKTIDPTMETEQAGLARQFLADASGRIVFTPRSGTAVPLRVPVYTAAKPVADIFVPKQVNFPRKASQSVLNLGGRGVDQGEDSEAYQSLISLFQLQATSPRLPDCADGGSEECAVNGTARGGDLRYVGATSTAPLAAEQGNPDDALLAFGLVTWDDWANIGSNTVPYIDIDTTGDGRPDFELYVTKAVSSDVLLVNTVSLNEPEFPSVDIQAVNGQLGDVDTNVFDTNVIALPVRLSALGIDPEADSHKITYTVGVAGYYGSPATGDVDGVSDPLTFDPLAPAYTVRGGGDPALSYFARPGTALVVDRDPAADPGEQVLGLLALNHHNASGDRSSVVRLHVAGQRPTPNL
>NZ_CP016353.1|WP_091799706.1|1397439_1399038_+|phosphoglycerate-dehydrogenase
MTIASQPVVLIAEKLAPSAVSVFGDEVEVRHVDGTDRPALLDAVKNADALLVRSATKVDAEVLGASGRLKVVARAGVGLDNVEVPAATERGVLVVNAPTSNIVSAAEHAVALLLSVARRVPAADQSLRAGEWKRSAYTGVELNGKTVGLVGFGKIGQLVAQRLAAFETKIIAYDPYTSPARAAQLGVELVSLDELLERADAISIHLPKTPETKGLIDAAALAKTKKGVIIVNAARGGLLDEDALANAVREGQVGGAGVDVFASEPTTESPLFGLPNVVVTPHLGASTAEAQDRAGTDVAKSVLLALRGDFVPDAVNVAGGGTVGDEVRPYLPLAHKLGTVLSAFSTQAPSSVAVVASGELSGEDVSVLQLAALRGVFSSVVENQVTFVNAPRLAEELGVQVQVTTEPESPNYRSQLTVRAVYADGTVNSVSGAVSGKEEIQKLIEVNGRHFDIRAEGNMLLLEYPDRPGIMGRVGTLLGEAGINIEAAQISQTTDRSDAVMLLRVDRAVDNQLLEPIGATVGARKIRAITFA
>NZ_CP016353.1|WP_091800786.1|1413595_1414528_-|NUDIX-hydrolase
MRAAGAVLWRRNPATEKLEVAVVHRNRYDDWSLPKGKLDQGETAPVAAVRELAEETGFDAVLGRFLTRVEYSVGEAAKTVDYFSARALGGLFAANEEVDELRWCSPELAVPMVGYDGDRAVLRQFMALPADLTTVLLVRHAKAGKRESWAGADDLRPLSEAGRRQAAALRVLLGTFGPDRVFAAPKLRCVQTVLGVADDLDRTVTTEPVFAEESFSSAPSATVARLLRIAAEGGTPVVCSQGGVIPALVRTLAERGGVGGVALPTGGTGSLASKKGSLWLLSFAADGDTPSLVAASYLPSPLPAPSPSVR
>NZ_CP016353.1|WP_176879593.1|1414556_1416800_-|RNA-degradosome-polyphosphate-kinase
MGNNARVSDDKSGVAPGTSADGSRRVTTSPPPVPTETDGKPAPPPTSVPSAPPAVTGGEQVPDALPDDRYFNRELSWQDFNARVLALAEDASQPLLERAKFLAIFASNLDEFYMVRVAGLKRRDETGLSVRSADGLTPREQLSYIAKRNQDLVERHTAAFEEHVRPSLAEKDIRIVRWSDLDGADHTRLSQYFTEQIFPVLTPLAVDPAHPFPYISGLSLNLAVTVRDPEGGTERFARVKVPNNVPRLVRIERQRDSQTATFLPLEELISAHLGELFSGMEVTEYHVFRVTRNADFEVEEDRDEDLLQALERELAQRRFGPPVRLEVAHDMSEHMLELLLRELEVDPRDVVEVPGLLDLTCLMQLLSVDRKELKDRPFVPATHPAFGERETPKSVFSTLRDGDVLVHHPYDSFSTSVQRFIEQAAADDKVLAIKQTLYRTSGDSPIVDALIDAAEAGKQVVALVEIKARFDEQANITWARTLERAGVHVVYGLVGLKTHCKVALVVRQEGGTIRRYCHIGTGNYNPKTARLYEDLGLLTADPAIGADLTDLFNVLTGYSRQATYRNILTSPHGIRRGILSYVADEIELAKAGKPAGVRIKCNSLVDEQVIDGLYRASAAGVEVDIVVRGICALKPGVPGLSDNISVRSILGRFLEHSRIFHFRGADAYWIGSADMMHRNLDRRIEAMVQVKDPKLAAQLGEVFDSALDPLTRCWVLSATGEWIPFPAETTQVRDHQIELLRKHGATG
>NZ_CP016353.1|WP_091799755.1|1416867_1417551_-|2-phospho-L-lactate-guanylyltransferase
MAVDLIVPLKPPVAGKSRLRGALGHAANAERHAALVLALASDTLLAATEAAGVRRVLVVGSDPKPLAELRALGVEVVGEDEPAAGGEGNVRGNPADTGLNAALRLGERLLRADDPGGIVGALQADLPALRASELSAAIEEADGRRAFTADRHGTGTTLLLSSNGGALDPRFGAGSAASHERSGATPLGLAAPSLRGDVDTAADLEHARLIGLGKRTTAVLEAAYLSR
>NZ_CP016353.1|WP_091800789.1|1417626_1418385_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MADREKGGFWVAAAAVLFYPLTWMGRSDYRGAERIPATGPALLVMNHVSHLDPAVDAVFVHRNRRVPRFMAKESLTKIPVFGKILLGSGGIPVSRGTSEAGDSLKAAHDTLSDGKIVLIYPEGTITKDPDGWLKRSYTGVARLALQNDVPVIPVARWGTQKIWNGYTKKFRPFPRKTVVHSVGEPVDLSAYRAKEPTSAVLREVTDLLMAEVLALLAEVRGEQPPSKPPATAPPAEPGDQDEKAEQAKEDGA
>NZ_CP016353.1|WP_091799758.1|1418386_1419397_+|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MTVQSVTVLGAGSWGTTFAKVLADAGRDVTMWARRPEVAAEIREEHTNNGYLPGVVLPGRVTATDDAALALDGAQAVVLAVPSQSLRANLTAWRSLLPREAILVSLAKGVELGTLKRMSEVIGEIAGVRSDDVVVVSGPNLAKEIARQQPAAAVFACADHDKAVAVQQASFNSYFRPYTNTDVVGCELGGACKNVIALSCGMAAGLGFGANTMATLITRGLAETARLGSKLGADPLTFAGLAGVGDLVATCASPLSRNRTFGELLGRGETVAMAQQAVGGQVAEGVMSCQSIRELARGVGVDMPITDAMFRVCHEGMNPARVGAELLGRQQKHEWS
>NZ_CP016353.1|WP_091800793.1|1419669_1420170_+|cysteine-dioxygenase-family-protein
MFAVPENTVSTAVSPTAANPLLRHPVRTALEFAADRERWRNILRYDPDERFASLLERTADQEVWLLSWLPGQEAEPHDHGLTTGAFTVVSGQLTETVTRKTVEGRVLTEVHTPSAGQSRVFGPGYVHQVRNTGPDPAISVHVYRAGGRTIRPYRLDPVEGPLPGTP
>NZ_CP016353.1|WP_091799761.1|1420166_1420838_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MPETPALSATPRSTLTRKKHRAAHERSALYDVLDNALVCHLGLVLHGSPVVLPTGYGRDGDTLYFHGSTGAGNLREAAEGVDVCVTVTILDGIVYARSLNNHSMNYRCAVVHGRARPLAGAEKEHGLKVITDQLSPGSWNYAREASAKELASVTVLALDLAEASVKMRAEGPGEEPEDLGTTDVWAGVLPVHTGFGSPVTAEYVPRSTPVPEHVASRAGTKYS
>NZ_CP016353.1|WP_091799764.1|1420905_1422288_+|PLP-dependent-aminotransferase-family-protein
MAVIDTALPVALDRTSETPLAVQLADALRASASTGHLRGGDRLPSTRALADRLGVSRTVTSAAYEQLHAEGWILGRHGSGTYVTTSPPSGRPERRAVVAGEEPPSNLLVLAPGLPWAEGLDKAAWRRAWRAASDTAPSWYAQRSGLPEYRAAIAEHLLRHRGLDAGTESVLATGGTTAAVIELAAAVLRPGDLVAIEEPGYQRAVHAFRRAGMRVVGAAVDAEGLRPDTVPDGVRAVYCSPAHQYPMGGRMSAARRVELVERARAEDFLVVEDDYDGELRYDVAPLPLLAALAPDVVAHLGTTSKILTPTLGAGWMVAPSSVTSAVLEYREVTGTRPSHAGQRVIVELARHGDLGRHLRRLRRELSERRSMLVGAFGKAGIPVLGDDAGAHLVVPLASAEDERERLASAKRRGLLLDGLGRHFARTPSTFGVAVGYAGCSREALRDSLGVLVDLLRVKPR
>NZ_CP016353.1|WP_091799767.1|1422299_1423397_+|D-alanine--D-alanine-ligase
MSSRKTRVAVVFGGRSTEHTISCVSAGSVLANLDPDRFEVVPIGITRAGGWVLGTSDPKALEIQGGELPTVETGKALVLAGDPTSNGVVSVEPGRETELLGTVDVVFPVLHGAFGEDGTIQGLLEMADIPYVGAGVLASAAAMDKEYAKKLLAAEGLPVGSYATVRRGRSTLDEAERERLGLPVFVKPARAGSSIGISKVTAWEQLDDAIALARQTDPKVLVEAAVTGREVECGVLEFPDGRVEASLPAEVRVLAEGADAWYDFETKYLGEDAELDIPAKLDDSIVERLREAAVRAFGALDCQGLARVDFFVGGDGELIINEVNTMPGFTTTSAYPKMWAVTGLDYPSLLATLVETAIARGTGLR
>NZ_CP016353.1|WP_091799770.1|1423468_1424041_-|DUF3515-domain-containing-protein
MSDTGAPPRVLIVIAAALAAGLAVVVGFFGLTSGDTGDSGDSAAPSQDQPAQRGPLPLVSIPAPDADSPECASLLAELPRELESAGEALPKRELAEPAPDATAAWGFDNPVVLRCGLDRPPELTRTSDTRAINDVTWLQVPAEDGTATWYVIDRPVYVALTVPPDTGTGPLQLISDIVGTTLPETPLRFD

Crispr_ID: NZ_CP016353_3

• CRISPR_ID: NZ_CP016353_3
• CRISPR_location: 1760485-1760582
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016353_3

Consensus_repeat	Method
CTGGAGGCCGCGTGAACGACAATG	CRISPRCasFinder

spacers of NZ_CP016353_3

>3.1|1760509|50|NZ_CP016353|CRISPRCasFinder
GCGGAGCCCCGTTCGCGTGGGCCGACCGGGTGCGGGTGTCCCGCAAGATA

CRISPR arrays and Neighbor proteins around NZ_CP016353_3

CRISPR arrays

The CRISPR arrays of NZ_CP016353_3

>merge|NZ_CP016353|3|1760485-1760582|CRISPRCasFinder
CTGGAGGCCGCGTGAACGACAATGGCGGAGCCCCGTTCGCGTGGGCCGACCGGGTGCGGGTGTCCCGCAAGATACTGGAGGCCGCGTGAACGACGATG

>NZ_CP016353|3|2|1760485-1760582|CRISPRCasFinder
CTGGAGGCCGCGTGAACGACAATG	GCGGAGCCCCGTTCGCGTGGGCCGACCGGGTGCGGGTGTCCCGCAAGATA
CTGGAGGCCGCGTGAACGACGATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091800593.1|1768918_1769476_-|RNA-2'-phosphotransferase	unknown	unknown	gnl|CDD|179136
NZ_CP016353.1|WP_170140063.1|1765388_1765544_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091800558.1|1752737_1753832_+|biotin-synthase-BioB	unknown	unknown	gnl|CDD|235755
NZ_CP016353.1|WP_091800928.1|1760590_1761442_+|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl|CDD|236125
NZ_CP016353.1|WP_091800556.1|1752013_1752736_+|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl|CDD|234625
NZ_CP016353.1|WP_091800582.1|1763685_1764792_+|histidinol-phosphate-transaminase	unknown	unknown	gnl|CDD|235115
NZ_CP016353.1|WP_091800585.1|1764788_1765388_+|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl|CDD|234873
NZ_CP016353.1|WP_091800570.1|1757857_1758865_+|quinolinate-synthase-NadA	unknown	unknown	gnl|CDD|236489
NZ_CP016353.1|WP_091800551.1|1748061_1749366_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl|CDD|273109
NZ_CP016353.1|WP_091800576.1|1761453_1762269_-|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl|CDD|143605
NZ_CP016353.1|WP_091800590.1|1768344_1768935_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP016353.1|WP_176879618.1|1757072_1757819_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|223979
NZ_CP016353.1|WP_091800596.1|1769527_1769989_-|redox-sensitive-transcriptional-activator-SoxR	unknown	unknown	gnl|CDD|133385
NZ_CP016353.1|WP_091800925.1|1756342_1757059_-|LON-peptidase-substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|366967
NZ_CP016353.1|WP_091800579.1|1762363_1763689_+|histidinol-dehydrogenase	unknown	unknown	gnl|CDD|234853
NZ_CP016353.1|WP_091800923.1|1755079_1756240_-|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP016353.1|WP_091800588.1|1765956_1768134_-|MMPL-family-transporter	unknown	unknown	gnl|CDD|225272
NZ_CP016353.1|WP_091800553.1|1749693_1751979_+|bifunctional-SulP-family-inorganic-anion-transporter/carbonic-anhydrase	unknown	unknown	gnl|CDD|223732
NZ_CP016353.1|WP_091800920.1|1754210_1754672_+|DUF2567-domain-containing-protein	unknown	unknown	gnl|CDD|371258
NZ_CP016353.1|WP_091800564.1|1754682_1755036_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133388

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091800593.1|1768918_1769476_-|RNA-2'-phosphotransferase	gnl|CDD|179136	PRK00819, PRK00819, RNA 2'-phosphotransferase; Reviewed.	1.79873e-85
NZ_CP016353.1|WP_091800558.1|1752737_1753832_+|biotin-synthase-BioB	gnl|CDD|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_CP016353.1|WP_091800928.1|1760590_1761442_+|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl|CDD|236125	PRK07896, PRK07896, carboxylating nicotinate-nucleotide diphosphorylase.	4.77819e-142
NZ_CP016353.1|WP_091800556.1|1752013_1752736_+|ATP-dependent-dethiobiotin-synthetase-BioD	gnl|CDD|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	2.82819e-62
NZ_CP016353.1|WP_091800582.1|1763685_1764792_+|histidinol-phosphate-transaminase	gnl|CDD|235115	PRK03317, PRK03317, histidinol-phosphate aminotransferase; Provisional.	0
NZ_CP016353.1|WP_091800585.1|1764788_1765388_+|imidazoleglycerol-phosphate-dehydratase-HisB	gnl|CDD|234873	PRK00951, hisB, imidazoleglycerol-phosphate dehydratase HisB.	2.3753e-118
NZ_CP016353.1|WP_091800570.1|1757857_1758865_+|quinolinate-synthase-NadA	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	1.90737e-165
NZ_CP016353.1|WP_091800551.1|1748061_1749366_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl|CDD|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NZ_CP016353.1|WP_091800576.1|1761453_1762269_-|carbon-nitrogen-hydrolase-family-protein	gnl|CDD|143605	cd07581, nitrilase_3, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	4.49899e-109
NZ_CP016353.1|WP_091800590.1|1768344_1768935_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	6.62851e-13
NZ_CP016353.1|WP_176879618.1|1757072_1757819_-|NUDIX-hydrolase	gnl|CDD|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	1.77396e-21
NZ_CP016353.1|WP_091800596.1|1769527_1769989_-|redox-sensitive-transcriptional-activator-SoxR	gnl|CDD|133385	cd01110, HTH_SoxR, Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator. Helix-turn-helix (HTH) transcriptional regulator SoxR. The global regulator, SoxR, up-regulates gene expression of another transcription activator, SoxS, which directly stimulates the oxidative stress regulon genes in E. coli. The soxRS response renders the bacterial cell resistant to superoxide-generating agents, macrophage-generated nitric oxide, organic solvents, and antibiotics. The SoxR proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the unusually long spacer between the -35 and -10 promoter elements. They also harbor a regulatory C-terminal domain containing an iron-sulfur center.	2.7121e-76
NZ_CP016353.1|WP_091800925.1|1756342_1757059_-|LON-peptidase-substrate-binding-domain-containing-protein	gnl|CDD|366967	pfam02190, LON_substr_bdg, ATP-dependent protease La (LON) substrate-binding domain. This domain has been shown to be part of the PUA superfamily. This domain represents a general protein and polypeptide interaction domain for the ATP-dependent serine peptidase, LON, Peptidase_S16, pfam05362. ATP-dependent Lon proteases are conserved in all living organisms and catalyze rapid turnover of short-lived regulatory proteins and many damaged or denatured proteins.	1.00775e-31
NZ_CP016353.1|WP_091800579.1|1762363_1763689_+|histidinol-dehydrogenase	gnl|CDD|234853	PRK00877, hisD, bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed.	0
NZ_CP016353.1|WP_091800923.1|1755079_1756240_-|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.88552e-61
NZ_CP016353.1|WP_091800588.1|1765956_1768134_-|MMPL-family-transporter	gnl|CDD|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	4.41337e-115
NZ_CP016353.1|WP_091800553.1|1749693_1751979_+|bifunctional-SulP-family-inorganic-anion-transporter/carbonic-anhydrase	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	4.87388e-105
NZ_CP016353.1|WP_091800920.1|1754210_1754672_+|DUF2567-domain-containing-protein	gnl|CDD|371258	pfam10821, DUF2567, Protein of unknown function (DUF2567). This is a bacterial family of proteins with unknown function.	1.10003e-07
NZ_CP016353.1|WP_091800564.1|1754682_1755036_-|MerR-family-transcriptional-regulator	gnl|CDD|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.00517e-38

Protein sequences

>NZ_CP016353.1|WP_091800570.1|1757857_1758865_+|quinolinate-synthase-NadA
MTVQADALVPYGGVDADAAWADEVRRLAERRDAVVLAHNYQLPEIQEIAHHTGDSLALSRIAAESEASTIVFCGVHFMAETAKILSPDKTVLIPDARAGCSLADSITGAQLREWKAQHPGAVVVSYVNTTAEVKAETDICCTSSNAVDVVASIPEDRDVLFCPDQFLGAHVKRETGRQNLHIWAGECHVHAGINGPELAERASASPEADLFIHPECGCATSALYLAGEGAVAPERVKILSTGDMLHAAKETKAASVLVATEVGMLHQLRKAAPDIDFRAVNDRASCRYMKMITPAALLRSLREGADEVEVDEETAARARASVRRMIEIGKPGGGE
>NZ_CP016353.1|WP_176879618.1|1757072_1757819_-|NUDIX-hydrolase
MRSHINSTTPLAHEVLAAVLQVRCATLRVLLWRRALDPHVGRWSLPGGRLRPDEDVEQSIRRQLAEKVDVKQLTHVEQLAVFSAPYRVPGPRVVATAFLGLVPSDVDPEVPEDTAWHPVDDLPRTAFDHEAIVLRARDRLRAKLSYTNLGFALAPREFTVSSLRELYSAALGYSVSATNLQRVLSRRGLLVPTGSTAPSGRAGGRPAALYSFAHDDMQVTDPFAVFKPPSPSRAPRSRTRGQARDAVT
>NZ_CP016353.1|WP_091800925.1|1756342_1757059_-|LON-peptidase-substrate-binding-domain-containing-protein
MTPERADSGATERMLPLFPLHTVLLPGAHLPLHIFEPRYRQLTADLTGERFPEPLFGVVAIRTSLIREVDNLDHVHAIGCGALLREAKGLPDGRFDIVTTGTRRFRLLDIETRSAPYLMAKVSWLDDTPMPSAKPDLAARLGDIARAAHHRYCASAWERDGWQSPAPDTDLRELAYLLAGDCLLPIDDRQALLEERHPLRRLRTVCRLLNREAGFLSKLHAVPVPFTDVDAPAAPSMN
>NZ_CP016353.1|WP_091800923.1|1755079_1756240_-|MFS-transporter
MCLLIATFAVGTDDFVIAGVLPRIANDLDVGEASAGQLVSVFSIVYAVSAPVLATLTARLPRRILFCGALFVFTAANVAAAFAPSFVVLMVLRIVAAVAAATVTPVAFALAASMSPAHRVGRNIGLVAAGLTMALVAGVPAGTWIGTQWSWRGSFLLVAALGVAAIAIASTGLRDQGTADPVPLRDRLRLLGSTPVLIGVAGTTLGGIGGLMTYTYIAPIVRDLSGAGSGTLAILIGVTGIAGAVGTAVGGRLTDRWGADRTLLLGLKGQVAASAALTAFGFAWQGNAPLPLTAAAFALWGFAGWAFNPPMNARLLALAPGAGTEAVALNTSGLYLGIALGGGIGGLVLPHHGGGGVVLAATVFGVLTVGLLTASIARYPATARAA
>NZ_CP016353.1|WP_091800564.1|1754682_1755036_-|MerR-family-transcriptional-regulator
MHIGELAERTGATKRALRYYEQEGLLSARREGNGYRDYDDDAVLTVHNIRQLLGTGLSIAEIRELAGCLAKDLSHGPVCAEAIELYRQRLDSVTERLEALHDTRERLTAHLAQTAGG
>NZ_CP016353.1|WP_091800920.1|1754210_1754672_+|DUF2567-domain-containing-protein
MVGLLGIPLGWIWSRLAPTQRMRVVSAEGDPIALQLESWHRFDALAIFALMGLATGLVVGVAVWFLRERRGPVVLLAAVGGSLLAAWLGMRMGIAFADSLHAVTGTPNVGDIVEKAPVLESGWVVIAQPLTVALAYGVLATWNSRDDLGRRLG
>NZ_CP016353.1|WP_091800558.1|1752737_1753832_+|biotin-synthase-BioB
MCRVAAPRATAAPEQAPDQFSPEGDAVPAATADSPIIPIAREQVLERGAGLEEDQILSVLRLPDEHLPELLALAHEVRLRWCGPEVEVEGIVSVKTGGCPEDCHFCSQSGRFPTPVRSAWLDIPGLVKAAAETAATGATEFCIVAAVRGPDERLLSQVRAGITAIRESGNDIQIACSLGMLTPEQVGELVDMGVHRYNHNLETARSHFPNVVTTHSWEERRETLALVKDAGMEVCCGGILGMGETAEQRAEFAAQLAELDPHEVPLNFLIPQPGTPYESYELVEGKDALRIVAAFRLAMPRTMLRFAGGRELTLGDLGAEHGMLGGVNAIIVGNYLTNLGRSAEADLDMLRELRMPIKALSETL
>NZ_CP016353.1|WP_091800556.1|1752013_1752736_+|ATP-dependent-dethiobiotin-synthetase-BioD
MTVLVISGTGTGVGKTVVTAAIAALARDRGQSVAVLKPAQTGVSQDQPGDLADVRRLAGDVVTREIRRYPDPLSPDAAARRRGLPPVTPAEVAKAASELHDEHELVLVEGAGGLLVPFDSGGGTIADVSWSLGAPVLIVAEPGLGTINATALTSEVATGRGLDVVGLVIGAWPARPDLAARCNVADLPVAAGAPLLGVLPDGLGEVTMAEFLAEARRGLSPWFGGEFDSDCFTGQVSAPQ
>NZ_CP016353.1|WP_091800553.1|1749693_1751979_+|bifunctional-SulP-family-inorganic-anion-transporter/carbonic-anhydrase
MTRKNGLATSDDRGASPWRKANEVLRHDVPASLVVFLVAVPLSLGIALASGAPIVAGLIAAIVGGVVAGAVGGSALQVSGPAAGLTIVMAETINTFGWAVTCAITVGAGALQVLFGLSRVARAALAISPAIVHGMLAGIGVTLVLGQLHVVLGGSAQSSSIDNILALPGQLVAHHDTAAILGVLTIAILLVWPKLPAAVRKIPGPLAAITVVTVLASVAGMAAQRVELPGDLLSVTLMPRLPEGHWFDFGVAVLTIALIASVETLLSAVAVDKMHNGKRANLNRELVGQGVANMTSGAIGGLPVTGVIVRSSTNVVAGARTRASAIMHGLWVLLFTVALASLIQSIPLAALAGLLVVVGAKLVDIKHIRQVLKHGDLPLYLVTLIGVVTIDLLSGVLLGIALSLVLMLGRTMWSGIHAEGEGQHRRLVIEGALTFLSVPRLSTVLNSMPEGSTVTLELVVDYLDHASFECLSSWQQAHERAGGTVVVDELGHPWFARGKSDAPTVRRRAAKPVVPRWLAPWSEWMAKDFGVHIPDQRTGPLRRGTSEFQNRTAPLVQETMSKLATDQRPHTLFITCGDARIVPNVITTSGPGDLFAVRNVGNFVPVGGAVTVSDDDSVGASIEYAVSVLGVREVVVCGHSSCGAMRALLGDTPGGLPSLARWLRHGAPSMRRHAGNTPVTLAGKVPELQGDRLALHNVLQQLDHLRRYPMVAEAERKGELQLTGMYFDVGNAQVYLFDPAEGAFVPAGAEAPAVEPEVKTG
>NZ_CP016353.1|WP_091800551.1|1748061_1749366_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNAANDATAADAELLALDARHVWHPYAPMPSTVAPLLVREASGACLRLADGRELVDGMSSWWAAVHGYRHPVLDAALAEQAGRMSHVMFGGLTHEPAIRLASTLAELTPDGLEHVFLSDSGSVSVEVALKMCLQYWRSRGEPAKRRMLTWRGGYHGDTFHPMSVCDPEGGMHALWRGVLPEQIFVPAPPSGFDTEPDQSYVDELAASVERNAGELAAVVVEPIVQGAGGMRFHHPGYLRALREITSANDVLLVFDEIATGFGRTGALFAAEHAGVTPDVLCLGKALTGGYLTMAATLCTPRVAEGISEGAVPVLAHGPTFMGNPLAAAVANASIGLLADGSWLPRVRRIEALLREGLAPAAGVPGVVDVRVLGAIGVVQLDRHVDMGEATRVLTANGVWLRPFRDLLYTMPPYVCTDGQVEQITAAMVKTTREV
>NZ_CP016353.1|WP_091800928.1|1760590_1761442_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MAGVPAEVLRRVVTTALAEDLAYGPDATTDATVPADAMATAAVTPRAAGVVSGIPAALAVFDEVLGDGYEVVRSGRDGSVPRAGEPVLVLRGPVRGLLTAERTALNLLCHLSGIATATAAWVAAVEGTGAAIRDSRKTLPGLRLLQKYAVRCGGGVNHRMGLGDAVLIKDNHVVASGSVTEALRLAREHAGDLPCEVEVDDLDQFAEALRAGADEILLDNFSPADCAKAVSLRDELSPGAKLESSGGLRLENARAYAESGVDYLAVGGLTHSSPALDLGMDLS
>NZ_CP016353.1|WP_091800576.1|1761453_1762269_-|carbon-nitrogen-hydrolase-family-protein
MLRVALCQLTSATDPERNLSLIREGVAEAARGGARVVILPEAAMARFGVPLGPLAQPVEGPWARAVGAIADEHDVLVVAGMFTPAGERVRNTLLVTGLGEHTGYDKIHLYDAFGFRESDTVEGGSSLVTVTVDDVKLGVATCYDVRFPELFQSLADAGTSAVALPASWGAGEGKREQWELLVRARALDSGNWILACGQADPAATGTEVNPKAPTGIGHSLVADPFGVVAARLGAGPGLLLADIEPSVAEKSRSATAVLANRTLHEGRTGRR
>NZ_CP016353.1|WP_091800579.1|1762363_1763689_+|histidinol-dehydrogenase
MLNRTDLRGRVPTPAQLRATLPRAEVDVDAALHQVRPVVEAVKERGVAAALDYAERFDKVRPASVRVPSAELAGALDRLDPVVRAAIEESISRARTVHADQRRTEVTTEVAEGGTVTERWVPVGRVGLYAPGGLAVYPSSVVMNVVPAQEAGVESLVVCSPPQAEFGGLPHPTILAAARLLGVDEVWAVGGAQAVALLAYGGTDTDGAPLDPVDMVTGPGNIYLTAAKRMLRGLIGIDSEAGPTEIAILADETADPDHVAADLISQAEHDTLAASVLVTTSEPLADAVEERLRHRVAATKHTQRVTEALSGPQSGVVLVSTVDDGLRVVDAYAAEHLEIQTADARAVAARVCNAGAVFVGPYAPVSLGDYCAGSNHVLPTGGFARHSSGLSVQTYLRGIHVIDYSAGALREVADKVVALAEAEDLPAHGEAVTARFPEAPA
>NZ_CP016353.1|WP_091800582.1|1763685_1764792_+|histidinol-phosphate-transaminase
MTSPTAGEVTIDQLPLREDLRGRSPYGAPQIDVAVRLNTNENPYPPPGELVDDVTDAVRAAAAELHRYPDRDAVALREDLAAYLSVATRVPLTERNVWAANGSNEILQQILQAFGGPGRSALGFEPSYSMHPIIAAGTRTEWLPAPRRADFSLDTEVAASLVAERSPDVVFLTSPNNPTGGSIPLGELEQVLRAAPGLVVVDEAYAEFSSQPSAATLLDSYPAKLIVSRTMSKAFAFAGGRLGYLAAAPAVVDALQLVRLPYHLSALTQAAARAALRHADATLASVARLASERDRVAEALTGLGFAPVPSDANFILFGRFADAPASWKSYVDHGVLIRDVGIEGHLRVTIGTPGENDAFLTASKEVPR
>NZ_CP016353.1|WP_091800585.1|1764788_1765388_+|imidazoleglycerol-phosphate-dehydratase-HisB
MSRVGKVERTTKESSIVVEVDLDGTGKAEVSTGVPFYDHMLNSFGVHGSLDLRIAAEGDVHIDAHHTVEDTAIVLGQAIRQALGDKAGIRRFGDAWIPMDETLAHAAVDVSGRPYCVHVGEPERFDTFTIGGNYPFVLTRHVFESLSFHAQLALHVRVVHGRDPHHIAEAQYKAVARALRAATEPDPRVGGVPSTKGVL
>NZ_CP016353.1|WP_170140063.1|1765388_1765544_+|hypothetical-protein
MGNAWVAVLLLAVAGFLVGGVFSTWKNSKGLAVALGVAAGLAIAGAVLWLR
>NZ_CP016353.1|WP_091800588.1|1765956_1768134_-|MMPL-family-transporter
MAIFLSRLGRFSFQRKRSVTGLWVVLLLALGIGALTLSGQMTNSVTIPGTESQRAIEQLESRFPEANVGGATARVAIAAPEGQTLDRAAVDEVVSQLRSAPQVTNVLDPFQAQTVSPDGRVALAQVSYSTQAFELSEADREGLLAAAEPGRDAGLEVEFGGDAIQGGFETNASEGVGVAIAAVVLIITFGSLIAAGLPLLTALIGVGVGMAGIMVTASFFELNANTPVLALMIGLAVGIDYALFIVSRYRHELETGKTPEDAAAHAVGTAGSAVVFAGLTVIIALAGLTVVGVPLLGEMGLAASATVAIAVLIAISLLPAVLGFAGNKVLGGRIPGLRGPSKSGPTAGERWARFISRHRVLVLTGSVVALLVVAIPAMSMRLGLPTDNTAAPDSTQRKAYDLISSGFGPGTNGPLTVVIEAGDNPEQSVQAAMQRIGGLDDVAAVMPPQFNAEGDTALLNVVPQSGPDTQATEDLVNDIRAEAGQLREQTGADIAVTGQTAMNIDVSKKMADALLPYLALIVGLAFILMMLVFRSLVVPLKATLGFLGSVIAAFGAVVAVFQWGWLGDLLGVEATGPIMSMLPILLIGVLFGLAMDYQVFLVTRMREEYVHGAEANTAMITGFRHGSRVVVAAALIMASVFAGFVLAEETLIQSIGFALAFGVAVDAFVVRMTIVPAVMSLLGKHAWWLPKWLDRILPNVDVEGEKLSAGNPPEGHGKSRELEPV
>NZ_CP016353.1|WP_091800590.1|1768344_1768935_+|TetR/AcrR-family-transcriptional-regulator
MTAGTVADGTRSRLLATALTLFSEHGVEGTSLQMIAAELGVTKAAVYYHFKTKDEITEAVAAPALRELDAVIDEALAQRSRGAQIDHALAGFADLVVQHRALVALFNSDPGIMRAIDRSLSGNENLMTRLMTILVGPEPDFADRITVHVVLVGLAMAGGAVEYRDIDDDTLRGQLIEVGRKLLGRRRKRAPANQNS
>NZ_CP016353.1|WP_091800593.1|1768918_1769476_-|RNA-2'-phosphotransferase
MHDIHRVRLSKRLSLYLRHAPERIGIQLDEGGWVEVDVLLAALAGKGIALTRAQLNEVVVTNDKRRFAFDHTGTRIRANQGHSVAVELDLPVRVPPALLYHGTVAAFLPTIRESGLLPMKRHDVHLSATVGTARTVGSRRGEPVVLTVDAAAMTREGHEFRLSANGVWLAREVPPRFLSIPTSSG
>NZ_CP016353.1|WP_091800596.1|1769527_1769989_-|redox-sensitive-transcriptional-activator-SoxR
MTKLADHLSIGQVAERSGVPHTALRFYEDRNLITSERSTGNQRRYSRSVLRRIAFIRAAQRVGLSLEQIGEALETLPKDHAPTKADWARLSRNWREELEARIDALQRLRDQLIGCVGCGCLSLRTCGLHNVDDRLARFGPGAPLLKPAAEGGI

Crispr_ID: NZ_CP016353_4

• CRISPR_ID: NZ_CP016353_4
• CRISPR_location: 2175123-2176010
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 14 spacers
• Cas_protein_info: csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NZ_CP016353_4

Consensus_repeat	Method
GGAACACCCCCGCTCGCGCGGGGAAGAC	CRISPRCasFinder
GGAACACCCCCGCTCGCGCGGGGAAGACN	CRT
GGAACACCCCCGCTCGCGCGGGGAAGAC	PILER-CR

spacers of NZ_CP016353_4

>4.1|2175151|38|NZ_CP016353|CRISPRCasFinder
GCCACACGGATGCACCGTTGACCCGGGTGCTCCGGGCG
>4.2|2175217|33|NZ_CP016353|CRISPRCasFinder
CACCGTCCATGGTGATCTCGACGCGTTCTACGC
>4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT
CTGGAGAAGGACCCGGCGCAGGCCGAGCGCTTC
>4.4|2175339|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
CATCCGGCGGAAGTACGCCGTCAGGATCGACCT
>4.5|2175400|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
CCTGTCCTTCGGAGTAGCCGCCGAACAGGAGGC
>4.6|2175461|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
GATATCAAGTTGCCGCGTAAGGCGACTCCGGAG
>4.7|2175522|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
GGTTGGATGTGCGTGAGGTCGCGGCGTGACGCG
>4.8|2175583|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
CCGGGTAGCAAACTCCATGCCGGGATTGTGACC
>4.9|2175644|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
AGGTAGATCGCAAGAGGGTCCAACCCGAAGTAC
>4.10|2175705|34|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
GGGGCTTTTCTGGCTGTGCTGCACGGCATGCGGC
>4.11|2175767|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
CCCGGCACTGACTAGCCTCCGTCGCGGCAGCGA
>4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
ATGAAGATGGCCGTCCTCAAGGTCGTCTCCGAG
>4.13|2175889|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
TATGGGTTGATGATCGCGCGACACCGTGATCCC
>4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR
GCTGGATCAACACAGCGGTGTTGATGGTCGTGG
>4.15|2175151|39|NZ_CP016353|CRT
GCCACACGGATGCACCGTTGACCCGGGTGCTCCGGGCGG
>4.16|2175218|32|NZ_CP016353|CRT
ACCGTCCATGGTGATCTCGACGCGTTCTACGC

CRISPR arrays and Neighbor proteins around NZ_CP016353_4

CRISPR arrays

The CRISPR arrays of NZ_CP016353_4

>merge|NZ_CP016353|4|2175123-2176010|CRISPRCasFinder,CRT,PILER-CR
GGCCTGGTCCCACTCGCGCGGGGAAGACGCCACACGGATGCACCGTTGACCCGGGTGCTCCGGGCGGGCAACACCCCGCTCACGCGGGGGAAGACACCGTCCATGGTGATCTCGACGCGTTCTACGCCCGGAACCCCCGCACGCGCGGGGAAGACCTGGAGAAGGACCCGGCGCAGGCCGAGCGCTTCGGAACACCCCCGCTCGCGCGGGGAAGACCATCCGGCGGAAGTACGCCGTCAGGATCGACCTGGAACACCCCCGCTCGCGCGGGGAAGACCCTGTCCTTCGGAGTAGCCGCCGAACAGGAGGCGGAACACCCCCGCTCGCGCGGGGAAGACGATATCAAGTTGCCGCGTAAGGCGACTCCGGAGGGAACACCCCCGCTCGCGCGGGGAAGACGGTTGGATGTGCGTGAGGTCGCGGCGTGACGCGGGAACACCCCCGCTCGCGCGGGGAAGACCCGGGTAGCAAACTCCATGCCGGGATTGTGACCGGAACACCCCCGCTCGCGCGGGGAAGACAGGTAGATCGCAAGAGGGTCCAACCCGAAGTACGGAACACCCCCGCTCGCGCGGGGAAGACGGGGCTTTTCTGGCTGTGCTGCACGGCATGCGGCGGAACACCCCCGCTCGCGCGGGGAAGACCCCGGCACTGACTAGCCTCCGTCGCGGCAGCGAGGAACACCCCCGCTCGCGCGGGGAAGACATGAAGATGGCCGTCCTCAAGGTCGTCTCCGAGGGAACACCCCCGCTCGCGCGGGGAAGACTATGGGTTGATGATCGCGCGACACCGTGATCCCGGAACACCCCCGCTCGCGCGGGGAAGACGCTGGATCAACACAGCGGTGTTGATGGTCGTGGGGAACACCCCCGCTCGCGCGGGGAAGAC

>NZ_CP016353|4|3|2175123-2176010|CRISPRCasFinder
GGCCTGGTCCCACTCGCGCGGGGAAGAC	GCCACACGGATGCACCGTTGACCCGGGTGCTCCGGGCG
GGCAACACCCCGCTCACGCGGGGGAAGA	CACCGTCCATGGTGATCTCGACGCGTTCTACGC
CCGGAACCCCCGCACGCGCGGGGAAGAC	CTGGAGAAGGACCCGGCGCAGGCCGAGCGCTTC
GGAACACCCCCGCTCGCGCGGGGAAGAC	CATCCGGCGGAAGTACGCCGTCAGGATCGACCT
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCTGTCCTTCGGAGTAGCCGCCGAACAGGAGGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GATATCAAGTTGCCGCGTAAGGCGACTCCGGAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGTTGGATGTGCGTGAGGTCGCGGCGTGACGCG
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCGGGTAGCAAACTCCATGCCGGGATTGTGACC
GGAACACCCCCGCTCGCGCGGGGAAGAC	AGGTAGATCGCAAGAGGGTCCAACCCGAAGTAC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGGGCTTTTCTGGCTGTGCTGCACGGCATGCGGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCCGGCACTGACTAGCCTCCGTCGCGGCAGCGA
GGAACACCCCCGCTCGCGCGGGGAAGAC	ATGAAGATGGCCGTCCTCAAGGTCGTCTCCGAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	TATGGGTTGATGATCGCGCGACACCGTGATCCC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GCTGGATCAACACAGCGGTGTTGATGGTCGTGG
GGAACACCCCCGCTCGCGCGGGGAAGAC

>NZ_CP016353|4|1|2175123-2176010|CRT
GGCCTGGTCCCACTCGCGCGGGGAAGAC	GCCACACGGATGCACCGTTGACCCGGGTGCTCCGGGCGG
GCAACACCCCGCTCACGCGGGGGAAGAC	ACCGTCCATGGTGATCTCGACGCGTTCTACGC
CCGGAACCCCCGCACGCGCGGGGAAGAC	CTGGAGAAGGACCCGGCGCAGGCCGAGCGCTTC
GGAACACCCCCGCTCGCGCGGGGAAGAC	CATCCGGCGGAAGTACGCCGTCAGGATCGACCT
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCTGTCCTTCGGAGTAGCCGCCGAACAGGAGGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GATATCAAGTTGCCGCGTAAGGCGACTCCGGAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGTTGGATGTGCGTGAGGTCGCGGCGTGACGCG
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCGGGTAGCAAACTCCATGCCGGGATTGTGACC
GGAACACCCCCGCTCGCGCGGGGAAGAC	AGGTAGATCGCAAGAGGGTCCAACCCGAAGTAC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGGGCTTTTCTGGCTGTGCTGCACGGCATGCGGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCCGGCACTGACTAGCCTCCGTCGCGGCAGCGA
GGAACACCCCCGCTCGCGCGGGGAAGAC	ATGAAGATGGCCGTCCTCAAGGTCGTCTCCGAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	TATGGGTTGATGATCGCGCGACACCGTGATCCC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GCTGGATCAACACAGCGGTGTTGATGGTCGTGG
GGAACACCCCCGCTCGCGCGGGGAAGAC

>NZ_CP016353|4|2|2175311-2176010|PILER-CR
GGAACACCCCCGCTCGCGCGGGGAAGAC	CATCCGGCGGAAGTACGCCGTCAGGATCGACCT
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCTGTCCTTCGGAGTAGCCGCCGAACAGGAGGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GATATCAAGTTGCCGCGTAAGGCGACTCCGGAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGTTGGATGTGCGTGAGGTCGCGGCGTGACGCG
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCGGGTAGCAAACTCCATGCCGGGATTGTGACC
GGAACACCCCCGCTCGCGCGGGGAAGAC	AGGTAGATCGCAAGAGGGTCCAACCCGAAGTAC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGGGCTTTTCTGGCTGTGCTGCACGGCATGCGGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCCGGCACTGACTAGCCTCCGTCGCGGCAGCGA
GGAACACCCCCGCTCGCGCGGGGAAGAC	ATGAAGATGGCCGTCCTCAAGGTCGTCTCCGAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	TATGGGTTGATGATCGCGCGACACCGTGATCCC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GCTGGATCAACACAGCGGTGTTGATGGTCGTGG
GGAACACCCCCGCTCGCGCGGGGAAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091795458.1|2165653_2166535_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP016353.1|WP_091798575.1|2171436_2172756_-|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
NZ_CP016353.1|WP_091795478.1|2171008_2171440_+|VOC-family-protein	unknown	unknown	gnl|CDD|319917
NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NZ_CP016353.1|WP_091795471.1|2169507_2170563_-|ACR3-family-arsenite-efflux-transporter	unknown	unknown	gnl|CDD|213563
NZ_CP016353.1|WP_091795510.1|2186999_2187515_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091795468.1|2169103_2169508_-|arsenate-reductase-ArsC	unknown	unknown	gnl|CDD|319973
NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl|CDD|378191
NZ_CP016353.1|WP_176879472.1|2172888_2173341_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NZ_CP016353.1|WP_091795465.1|2167863_2169117_+|hypothetical-protein	unknown	unknown	gnl|CDD|115789
NZ_CP016353.1|WP_091795475.1|2170559_2170922_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|223713
NZ_CP016353.1|WP_170140093.1|2173497_2174583_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|187776
NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244
NZ_CP016353.1|WP_091795507.1|2186279_2186786_+|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_CP016353.1|WP_170140048.1|2166656_2167847_+|CoA-transferase	unknown	unknown	gnl|CDD|367110

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	2.1e-30	100.6	0.0
NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	3.1e-104	342.5	0.6
NZ_CP016353.1|WP_091795475.1|2170559_2170922_-|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	5.3e-23	76.4	0.0
NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	9.5e-51	166.8	0.9
NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	7.8e-60	197.5	0.0
NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	4.2e-116	383.4	0.2
NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	1.4e-60	199.8	1.0
NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.1e-32	106.8	0.3
NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.6e-113	374.7	5.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091795458.1|2165653_2166535_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.80442e-37
NZ_CP016353.1|WP_091798575.1|2171436_2172756_-|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	5.69375e-110
NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.22015e-121
NZ_CP016353.1|WP_091795478.1|2171008_2171440_+|VOC-family-protein	gnl|CDD|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.19403e-45
NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	2.16549e-133
NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.82596e-80
NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	5.04119e-157
NZ_CP016353.1|WP_091795471.1|2169507_2170563_-|ACR3-family-arsenite-efflux-transporter	gnl|CDD|213563	TIGR00832, Uncharacterized_transporter_slr0944, arsenical-resistance protein. The Arsenical Resistance-3 (ACR3) Family (TC 2.A.59) The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport. [Cellular processes, Detoxification, Transport and binding proteins, Anions].	3.30119e-144
NZ_CP016353.1|WP_091795468.1|2169103_2169508_-|arsenate-reductase-ArsC	gnl|CDD|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	4.15213e-48
NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	3.69922e-30
NZ_CP016353.1|WP_176879472.1|2172888_2173341_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	5.76686e-26
NZ_CP016353.1|WP_091795465.1|2167863_2169117_+|hypothetical-protein	gnl|CDD|115789	pfam07158, MatC_N, Dicarboxylate carrier protein MatC N-terminus. This family represents the N-terminal region of the bacterial dicarboxylate carrier protein MatC. The MatC protein is an integral membrane protein that could function as a malonate carrier.	4.04494e-24
NZ_CP016353.1|WP_091795475.1|2170559_2170922_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	3.8623e-21
NZ_CP016353.1|WP_170140093.1|2173497_2174583_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	5.12229e-69
NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.38382e-51
NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.2668e-74
NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	7.58097e-41
NZ_CP016353.1|WP_091795507.1|2186279_2186786_+|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	9.26854e-44
NZ_CP016353.1|WP_170140048.1|2166656_2167847_+|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	1.28531e-126

Protein sequences

>NZ_CP016353.1|WP_170140093.1|2173497_2174583_+|MFS-transporter
MTSELLPVGLLTPVGSALGVSEGTAGLMVTIPGLVAAVSAPLVTVATGRVDRRVVLAVLIGLVGAANLVSSVATSFALVLVARFLVGISVGGFWSLAGGIALRLVPPKHVPRATAVIFGGVETASVLGVPAGTFLGDLSGWRTAFAAVGVLGLISLACVVLLVPKLPARRTIGFVDLRDLFTGNRGVRKGITVTFLVITGHFLAYTFLRPILGEAGVEAKATGALLLAFGVAGICGNFLAGALIGNRLRLTVTGIGVLLGTAMVLLAVVELTTFTAGAILVLWGLGYGAVPVTVQTWIIKAAGESTEAASSLNTAAFNLSIALGALAGGLAINHVATTSVLWIGAALVMLVLPVVRSGARA
>NZ_CP016353.1|WP_176879472.1|2172888_2173341_+|carboxymuconolactone-decarboxylase-family-protein
MTTFQVPERMNFSAVAPKILKAVLALDSAARQGLDPVLVELVQIRASQLNRCAYCIDYHSTDAREAGETEERIYQLSAWQEAGVYTLRERAALALTEHVTLLPGGVPDEVYDRAAEHFDEAELARLIAVIFTVNTWNRMNVTTRKTPGTP
>NZ_CP016353.1|WP_091798575.1|2171436_2172756_-|PLP-dependent-aminotransferase-family-protein
MHALREAIRSGRLAPDTRLPSYRGLALDLGIARNTVAAAYAELAEEGWLTSRQGSGTRVARRATPPEPDTTRRARRPAPRKAVHDLLPSSPDAAAFPRAAWLSSARRALTAAPNDAFGAGDPRGRPELRQALAEYLARARGVRTEADRIVVCSGFAHGLRLLAKVLGGPIATESYGLAFHRSILNDAGASTVALTIDSHGARVDELPGTGATSVLLTPAHQYPTGGPLHPRRRAEVIDWARATGGLVLEDDYDGEFRYDREPVGAVQGLDPGHVVYLGSTSKSLSPALRLGWLVLPPALVGDVLRAKGERELWSGVVDQLTLADFLASGGYDKHLRRMRRSYRRRREQLVGTLAERAPHIGVSGIAAGLHAVLELPPGTEETALRAARRLGIALDGLGPYRHPASTMPPRDGVVIGYATPPEHGFTAALDALCLALPDG
>NZ_CP016353.1|WP_091795478.1|2171008_2171440_+|VOC-family-protein
MSRVQIALRVGDLAASIDFYTKLFGVEPSKLRPGYANFAIEDPALKLVLIEGEPGQATVMDHLGVEVGSTGEVEAATQRLTGEGLDTLTEDDTTCCYAVQDKVWVHGPGQEPWEVYTVKADSQDYGTDSAAPAACCTPEAKAG
>NZ_CP016353.1|WP_091795475.1|2170559_2170922_-|helix-turn-helix-transcriptional-regulator
MPKQLPLTAIDACCSPLAREPLSAEQAAELSGLFKAMADPVRLRLLSLIASHSGGEACVCDLTDAFDLSGPTISHHLKVLRQSGLITGERRGTWVYYRVHPEVLARLSAVLVPGEQNVPA
>NZ_CP016353.1|WP_091795471.1|2169507_2170563_-|ACR3-family-arsenite-efflux-transporter
MTTTVARQLSKLDRFLPVWIAAAMAVGLLAGRSIPGLSTALNAVSVDGISLPIALGLLVMMYPPLAKVRYDRLGTVTGDRRLLWSSLVLNWVLGPALMFALAWLMLPDLPEYRTGLIIVGLARCIAMVIIWNDLALGDREAAAVLVALNSVFQVIAFGLLGWFYLSVLPGWLGLDTTTLSVSGWQITKSVLIFLGIPLLAGYLTRRIGERARGRTWYETTFLPRIGPIALYGLLFTIVVLFALQGEQIVGRPLDVARIALPLLTYFGLMWAGSYALGRALELSDERTTTLAFTAAGNNFELAIAVAIATFGATSGQALAGVVGPLIEVPVLVALVYVSLALRRRAAARKVS
>NZ_CP016353.1|WP_091795468.1|2169103_2169508_-|arsenate-reductase-ArsC
MTTPEVLFVCVHNAGRSQMAAALLDHHAEGRVVVRSAGSAPADDINPAVIEVMGEIGIDLTTAFPKPLTTDAVRAADVVITMGCGDACPVYPGKRYLDWRLEDPAGLTAEQIRPIRDDIDRKVQELLTDLLTRS
>NZ_CP016353.1|WP_091795465.1|2167863_2169117_+|hypothetical-protein
MTMAVVSIIVLVALFAATLIPAFDLGLGALAAAFVVGLAAGVPADEVTGFFPADFFVLIVGVTALFAVAHLNGTLDWLLGLLLRLVGGRLALVPLVPFVIGAVLTAVGTLPAAATAIVAPIALGLAARYGISPLVAAVLGITGIISGLLSPLAVYGVTARELSAKFGIELPGSAPVAFLLGGLLTGLVVSLVCLLIGLRTGAVPRGRVAGDPPPESGTAPVPATKSARVLTVLCLLAVVVLSVGFEMNIGYLGITGALVLQLVLRLEPGAVVAKIPWSVVLLIGGLLTYVGLMQHLGAFEQISDLLRVEGSAALSLLVLCYIAGITSFAASSIAVFVTAMPLLPPLVEAGVSPVGGVLAIALASVLVDINPLGITGGLILGAAEPSARPRLFRQLLTYGLISIAVAPALAWLAFSFW
>NZ_CP016353.1|WP_170140048.1|2166656_2167847_+|CoA-transferase
MTVGPLSGVRVLDVSTILAGPLASSLLGEFGAEVIKIEQPGEGDPARRYPPLADDGVSEAWAMLGRTKRSVTIDLHAPEAAALVGKLAATAEVVVTNFRPATLRRFRIDFDDLRAYRPDLVMVHVSAFGRTGPYADRPGFARVAEAFAGLTYRTGDPERPPVFAGYPVADGVTGIYAAFAAMLALRQRDHTGEAQLADIPLYEPLLRMMEDFVVEYGVTGRSRERQGNRNPHISPNSLYRTRDGRWLALPASTEQMWRRLVAVMAAPDLAVHDTMTARLENRDEIESRVAEFVAAHDLEPLMALLVEAGVAAGPVNSASDIVADPHIRARGSVVELARGEGEPRLPMQAPAGRFSGFEATIGGRAPGLGEHTAEVLREAGGLTGPEIEKLRQRGVI
>NZ_CP016353.1|WP_091795458.1|2165653_2166535_-|LysR-family-transcriptional-regulator
MRVERVRYFLAAIETGSLRAAAARCEVSQPSVGQQIAALEEELDVVLLTRGKHGVRPTAAGQALLEPLRRLVAAEEELRESAMAADGAYHGKVRIGAVSVTAETIVAPVVGRLRERHAGLRFTVREGGSAEVERAVLDGELDFAVVTVPVSPAAPGLRRVPLVSAPMGIYAPGDHPLAGREHLYWRDLETWPIVTMRNGTTLWELLHQQVSNPDIVVEAMSARSLKVMVAESAGLGVLAKFETSADIPGLVWIPLRDAAPVRICLTRRKHTRPSRAANIVAQLIRAKAEELSA
>NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MTVIVVAACPTGLRGHLTRWLLEISPGVFVGTINARVRELVWVRVVDMVKSGRAIMVYSANNEQGLAFSVHHHNWEPVDFEGVNLMLRPNTTSDVDQSPAPRPTGWSTAARRRKFGR
>NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MPDIPGAKPVPLSQLTRAEDRLTFIYLEHSVVHRDANAITAHDARGTVHIPAATLGALLLGPGTTVSQQAMVLLAESGSTAVWVGEHGVRYYAHGRSLARSSRLLEAQAALVSDRQSRLHVARRMYAMRFPDDDTTGLSMQQLRGKEGARVRRIYRENANRTGIEWTRRDYDSADFDSGTVVNQALSAANTSLYGVVHAAIVALGCAPGLGFVHTGHVRSFVFDIADLYKADIAIPIAFDIATAQPMDVGAETRRAVRDYLRRHAFLERCVSDVKDLLRGEDEEPVEYGPDALDGPDVVMLWDYDDGEVEGGVSYPEVPDL
>NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MSHLTRYEFNTARRGTRWLLSSPQRLHAAVLSSFPSELTQSAEDGRILWRLDSRPHQTLLYMVSPHRPDLTHLVEETGWPRIREWETRDYDPLLTRLAPGQRWTFRLTANPAQSRRRSETASRSQRFGHVTVAQQTQWLLDRVQKHGFAVVEGKSKEPDVAVQGRHTWKFTRSGQTVTIATVVFEGTLEVTDPAALRFALINGIGPAKGYGCGLLTLAAAR
>NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTVLLLRLAAPLQSWGTGSRFSRRNTDRVPSKSGIIGLLAAAEGRRRTESIADLRQLRLGVRIEQAGQIERDFQTAQSVDRSESMPLSYRFYLADAVFLVAIEGEPELLDGLNESLRRPAFPLFLGRRSCPPTGPLVLAIREGTIAEVFRNEPWQATSRVRKARRDSLVTLETVIDCEAGTDGSILVRDDPASFDPRHRKHDWRSVLPDSVAGVTNPDYAHEPMDLLPEDVT
>NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MNRTIVDIHVIQTVPPSNINRDDTGSPKTAVYGGKRRARVSSQAWKRATRDDFSSFLDLSELGMRTKRVVELLTESIQKQDTDLVDQAEELATEVLSKAGIKLKAARKKDAPQEAGYLLFLSNNQIEALAELAVDAAHNGDGTVSKQDAKARADRQHSVDIALFGRMVADDADLNVDAAAQVAHALSVHEVSNEYDYYTAVDDHKRADEEEDAGAGMIGTVEFNSSTLYRYATVDVDRLRDNLGDVEATRRAVVAFARSFVTSMPTGKQNTFANRTLPDAVLILVRDTQSMNLVGAFEEVVDERESSGRIGSALTRLVGYGTDLHAAYDETPVAGWSVGIGERAEVLTGLASRTSFESATTALSELVAERLGTS
>NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTQVRPNKPWIGSITRDVVNKRVKGLQREALRDRPEAVAALARLRRGVGKPPGEIGDILTYTLDDQLVREHEVNRDQPTVGEFAAHHSLTLYALHQQAQNKAMHHEGPQYELGRSIRMLIADHTFPDRHPVITRFQAFSTSDSLGELVHHLRGIIQLLRGESVPLDYGLLAEKLVRWQLRGEDQVRMVWSREFYIMRRRDAKPRTDTTDTTPENS
>NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MTGSDSHPFDLLTEPWLPVRTISGETVELSLREVFGKAHDLVAISGDLATQDVALLRLLLAVLHRAVGGPRDLDHWEQLWSGKELPHARIEDYLDSHRDRFALFHPETPFFQVAGLRTAKGETAELSKLIADVPNGHPFFTTRLGSDLSLSFAEAARWVVHCQAFDPSGIKTGPVDDPRTKGGRGYPIGTGWAGRVGSVLVEGATLRDTLLLNLIASDFGDTARSPGDDLPAWERPVALPGGTRDPSGPLDLYTWQARRIRLVPDNGKVTSVLICNGEAIDTKNRHNDEPLTAWRRSAAQEKQHRLPQVYMPRQHDPSRAIWRGLQSLLPAAFENSVQNATAASGLTAVVLDWVSGLTLEGALPGDFPLRLRTVGMKYGSKDAVTEDIVDDALSLHAVLLRQDAVELVGTVLSCVSAAEQAARALGQLALNVAQAAGKSPPKPSGANPSDVSDRDRATELAYGQLDIAFRKWIPGLGPKTDPTQAQREWHHNVKQEIDPLGDDILARAPAVAITGRQVGGRLVTAAHAQSWFYLALSKAIPMAFDRGPQGSSS
>NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3
MSNGIAWLSPWGKTTRDQNGIVERWLPLIQHLEDSAGVARLIVDEWLPHQTRSFLERDLEGSPVTASTLVVWLAGIHDVGKASPAFAVQVPELTNRMTRHGLAMNPLQAKDSDRSKVSHGLVGHLAVRDWLTHEIGLPSRGLANQLASVVGSHHGVAPEPTQLSLVTRRPDLAGDTAWQDARRAILRHMTGVVCEPSLLTSLSESRMSKSSLVLLTAVVIMADWIASNEDFFPFEPISTADRQPWLPDRKTTAARVEKAWEQLDLPPRWLPVAPCPDIQDLFRTRFPQVSHARPVQVAMTEVARAIRGAGMVIVEAPMGVGKTEAALVAAEELAHTSGAGGVLIALPTQATTDAMFSRVREWIKALPSNDSTAISLVLAHGKASLNDEYAGLMRRGRFADVGESNDENVVVHEWLRGRKKGLLASFAVCTIDQILVGGLKSRHVMLRHLALAGKVVVIDEVHAYDVYMSQYLHRILHWLGTYGVPVVLLSATLPPARRAELLHAYGEGSGTSAVIPDESDVGYPAVLSSRGEVRTVHADAGPEVTLDRLPDDLDTLVAYLRTHLADGGCAAVVRNTVTRVQETADRLAAEFGENAITVNHSRFLACDRSRIDKDLVHRFGPSTRDNSRPSTHIVVASQVLEQSLDVDFDLLVTDLAPADLVLQRMGRLHRHLRDRPPGVRFPRCAITGVEDWAAFPVRAVTGSRRVYREHPLLRSAALFTDRSTVTLPTDIPSLVRDAYADTPLGPASWQPEMADAAKRASADAVERVNRAATYLLGDPDSPERSLVGWLRAGVGDGESQQGLAQVRDGAESLEVLVVQRDHDGGLRTADWLERGAGIQLPLDEPVPSRDARVVAACTLRLPLALSHPGVIDAVIAALEHDAHPDSFRATPMLAGQLILALDDNRQTGIRAGDQTFLLTYDLHKGLLHDRI
>NZ_CP016353.1|WP_091795507.1|2186279_2186786_+|DinB-family-protein
MNEDPRTHPPREGDERASLTGFLDFQRQTLAVKCAGLNAEQLRRKTVPPSDMSLIGLVRHMAEIERGWFEKVMNGEQLDTYWGMRPDGDYAEFDVDDAEPDEAFAVWNKACARSSEIVAAIESLDTVRHHGDLGYSLRWVLIHMIEEYARHNGHADLLRERIDGETGE
>NZ_CP016353.1|WP_091795510.1|2186999_2187515_+|hypothetical-protein
MARASRDTATRESGSGRRRASGIYGAIVAAAVLTAAGEALSTAALAVAVVATLLVYWLAEEYAVLLGQHAEAGKLPSAGRIRAELAATWPMVTASYGPLVALLLAWLAGASPVTAANVGLVAAVLLLVFHAWSAGMAARLRGVPLIAVTTVAALLGVLMVVLKNFVLLHLH

Crispr_ID: NZ_CP016353_5

• CRISPR_ID: NZ_CP016353_5
• CRISPR_location: 2185392-2186091
• CRISPR_type: TypeI-E
• Repeat_type: I-C,I-E,II-B
• Spacer_info: 11 spacers
• Cas_protein_info: cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

Consensus repeat of NZ_CP016353_5

Consensus_repeat	Method
GGGACCACCCCCGCGTGTGCGGGGAAGAC	CRISPRCasFinder
GGACCACCCCCGCGTGTGCGGGGAAGAC	CRT
GGACCACCCCCGCGTGTGCGGGGAAGAC	PILER-CR

spacers of NZ_CP016353_5

>5.1|2185421|32|NZ_CP016353|CRISPRCasFinder
CTGCTCGTCGTCGACCAGGCGAAGTACTTCAA
>5.2|2185482|33|NZ_CP016353|CRISPRCasFinder
TCAAATTGCCGTAACGGCGGGACCCGTGCTGCC
>5.3|2185544|31|NZ_CP016353|CRISPRCasFinder
TGGAGCGGTGGCGCGGCGTCGGACTGAGGGC
>5.4|2185604|32|NZ_CP016353|CRISPRCasFinder
TCGGAGGGCACCGGCGCGTTGATCTCGGCAAC
>5.5|2185665|32|NZ_CP016353|CRISPRCasFinder
GACCGCGAATACGTGCGCGGGCTCATGGCCGA
>5.6|2185726|32|NZ_CP016353|CRISPRCasFinder
TACATCAAGGGAATCAACACCTGGAAGAACCA
>5.7|2185787|32|NZ_CP016353|CRISPRCasFinder
TACGAAACCCAACAGAAACTGCTGTTCCTGTG
>5.8|2185848|32|NZ_CP016353|CRISPRCasFinder
GATCGTCGATGGTGTCCGGTCGGTCGTAGAGA
>5.9|2185909|32|NZ_CP016353|CRISPRCasFinder
CCGCTGCCGAAGGTGCTCGTGTACTGGGAGTA
>5.10|2185970|32|NZ_CP016353|CRISPRCasFinder
GTGTCCCGAACCACTACCGCGCGTCCTATGTG
>5.11|2186031|32|NZ_CP016353|CRISPRCasFinder
GATCCTGGGGCCGACCGGCTCGCCTTGCTCCA
>5.12|2185421|33|NZ_CP016353|CRT
CTGCTCGTCGTCGACCAGGCGAAGTACTTCAAC
>5.13|2185482|34|NZ_CP016353|CRT,PILER-CR
TCAAATTGCCGTAACGGCGGGACCCGTGCTGCCA
>5.14|2185544|32|NZ_CP016353|CRT
TGGAGCGGTGGCGCGGCGTCGGACTGAGGGCG
>5.15|2185604|33|NZ_CP016353|CRT
TCGGAGGGCACCGGCGCGTTGATCTCGGCAACG
>5.16|2185665|33|NZ_CP016353|CRT
GACCGCGAATACGTGCGCGGGCTCATGGCCGAG
>5.17|2185726|33|NZ_CP016353|CRT
TACATCAAGGGAATCAACACCTGGAAGAACCAG
>5.18|2185787|33|NZ_CP016353|CRT
TACGAAACCCAACAGAAACTGCTGTTCCTGTGG
>5.19|2185848|33|NZ_CP016353|CRT
GATCGTCGATGGTGTCCGGTCGGTCGTAGAGAC
>5.20|2185909|33|NZ_CP016353|CRT
CCGCTGCCGAAGGTGCTCGTGTACTGGGAGTAC
>5.21|2185970|33|NZ_CP016353|CRT
GTGTCCCGAACCACTACCGCGCGTCCTATGTGG
>5.22|2186031|33|NZ_CP016353|CRT
GATCCTGGGGCCGACCGGCTCGCCTTGCTCCAG
>5.23|2185544|39|NZ_CP016353|PILER-CR
TGGAGCGGTGGCGCGGCGTCGGACTGAGGGCGCGGACCA
>5.24|2185611|33|NZ_CP016353|PILER-CR
TCGGAGGGCACCGGCGCGTTGATCTCGGCAACG
>5.25|2185672|33|NZ_CP016353|PILER-CR
GACCGCGAATACGTGCGCGGGCTCATGGCCGAG
>5.26|2185733|33|NZ_CP016353|PILER-CR
TACATCAAGGGAATCAACACCTGGAAGAACCAG
>5.27|2185794|33|NZ_CP016353|PILER-CR
TACGAAACCCAACAGAAACTGCTGTTCCTGTGG
>5.28|2185855|33|NZ_CP016353|PILER-CR
GATCGTCGATGGTGTCCGGTCGGTCGTAGAGAC
>5.29|2185916|33|NZ_CP016353|PILER-CR
CCGCTGCCGAAGGTGCTCGTGTACTGGGAGTAC
>5.30|2185977|33|NZ_CP016353|PILER-CR
GTGTCCCGAACCACTACCGCGCGTCCTATGTGG
>5.31|2186038|33|NZ_CP016353|PILER-CR
GATCCTGGGGCCGACCGGCTCGCCTTGCTCCAG

CRISPR arrays and Neighbor proteins around NZ_CP016353_5

CRISPR arrays

The CRISPR arrays of NZ_CP016353_5

>merge|NZ_CP016353|5|2185392-2186091|CRISPRCasFinder,CRT,PILER-CR
CCGGACCGCCCCGCGGGTGTGGGGAAGACCTGCTCGTCGTCGACCAGGCGAAGTACTTCAACGGACCACCCCCGCGTGTGCGGGGAAGACTCAAATTGCCGTAACGGCGGGACCCGTGCTGCCAGGACCACCCCCGCGTGTGCGGGGAAGACTGGAGCGGTGGCGCGGCGTCGGACTGAGGGCGCGGACCACCCCGCGTGTGCGGGGAAGACTCGGAGGGCACCGGCGCGTTGATCTCGGCAACGGGACCACCCCCGCGTGTGCGGGGAAGACGACCGCGAATACGTGCGCGGGCTCATGGCCGAGGGACCACCCCCGCGTGTGCGGGGAAGACTACATCAAGGGAATCAACACCTGGAAGAACCAGGGACCACCCCCGCGTGTGCGGGGAAGACTACGAAACCCAACAGAAACTGCTGTTCCTGTGGGGACCACCCCCGCGTGTGCGGGGAAGACGATCGTCGATGGTGTCCGGTCGGTCGTAGAGACGGACCACCCCCGCGTGTGCGGGGAAGACCCGCTGCCGAAGGTGCTCGTGTACTGGGAGTACGGACCACCCCCGCGTGTGCGGGGAAGACGTGTCCCGAACCACTACCGCGCGTCCTATGTGGGGACCACCCCCGCGTGTGCGGGGAAGACGATCCTGGGGCCGACCGGCTCGCCTTGCTCCAGGGACCACCCCCGCGTGTGCGGGGAAGAC

>NZ_CP016353|5|4|2185392-2186091|CRISPRCasFinder
CCGGACCGCCCCGCGGGTGTGGGGAAGAC	CTGCTCGTCGTCGACCAGGCGAAGTACTTCAA
CGGACCACCCCCGCGTGTGCGGGGAAGAC	TCAAATTGCCGTAACGGCGGGACCCGTGCTGCC
AGGACCACCCCCGCGTGTGCGGGGAAGAC	TGGAGCGGTGGCGCGGCGTCGGACTGAGGGC
GCGGACCACCCCGCGTGTGCGGGGAAGAC	TCGGAGGGCACCGGCGCGTTGATCTCGGCAAC
GGGACCACCCCCGCGTGTGCGGGGAAGAC	GACCGCGAATACGTGCGCGGGCTCATGGCCGA
GGGACCACCCCCGCGTGTGCGGGGAAGAC	TACATCAAGGGAATCAACACCTGGAAGAACCA
GGGACCACCCCCGCGTGTGCGGGGAAGAC	TACGAAACCCAACAGAAACTGCTGTTCCTGTG
GGGACCACCCCCGCGTGTGCGGGGAAGAC	GATCGTCGATGGTGTCCGGTCGGTCGTAGAGA
CGGACCACCCCCGCGTGTGCGGGGAAGAC	CCGCTGCCGAAGGTGCTCGTGTACTGGGAGTA
CGGACCACCCCCGCGTGTGCGGGGAAGAC	GTGTCCCGAACCACTACCGCGCGTCCTATGTG
GGGACCACCCCCGCGTGTGCGGGGAAGAC	GATCCTGGGGCCGACCGGCTCGCCTTGCTCCA
GGGACCACCCCCGCGTGTGCGGGGAAGAC

>NZ_CP016353|5|2|2185393-2186091|CRT
CGGACCGCCCCGCGGGTGTGGGGAAGAC	CTGCTCGTCGTCGACCAGGCGAAGTACTTCAAC
GGACCACCCCCGCGTGTGCGGGGAAGAC	TCAAATTGCCGTAACGGCGGGACCCGTGCTGCCA
GGACCACCCCCGCGTGTGCGGGGAAGAC	TGGAGCGGTGGCGCGGCGTCGGACTGAGGGCG
CGGACCACCCCGCGTGTGCGGGGAAGAC	TCGGAGGGCACCGGCGCGTTGATCTCGGCAACG
GGACCACCCCCGCGTGTGCGGGGAAGAC	GACCGCGAATACGTGCGCGGGCTCATGGCCGAG
GGACCACCCCCGCGTGTGCGGGGAAGAC	TACATCAAGGGAATCAACACCTGGAAGAACCAG
GGACCACCCCCGCGTGTGCGGGGAAGAC	TACGAAACCCAACAGAAACTGCTGTTCCTGTGG
GGACCACCCCCGCGTGTGCGGGGAAGAC	GATCGTCGATGGTGTCCGGTCGGTCGTAGAGAC
GGACCACCCCCGCGTGTGCGGGGAAGAC	CCGCTGCCGAAGGTGCTCGTGTACTGGGAGTAC
GGACCACCCCCGCGTGTGCGGGGAAGAC	GTGTCCCGAACCACTACCGCGCGTCCTATGTGG
GGACCACCCCCGCGTGTGCGGGGAAGAC	GATCCTGGGGCCGACCGGCTCGCCTTGCTCCAG
GGACCACCCCCGCGTGTGCGGGGAAGAC

>NZ_CP016353|5|3|2185454-2186091|PILER-CR
GGACCACCCCCGCGTGTGCGGGGAAGAC	TCAAATTGCCGTAACGGCGGGACCCGTGCTGCCA
GGACCACCCCCGCGTGTGCGGGGAAGAC	TGGAGCGGTGGCGCGGCGTCGGACTGAGGGCGCGGACCA
CCCCGCGTGTGCGGGGAAGACTCGGAGG	GCACCGGCGCGTTGATCTCGGCAACGGGACCAC
CCCCGCGTGTGCGGGGAAGACGACCGCG	AATACGTGCGCGGGCTCATGGCCGAGGGACCAC
CCCCGCGTGTGCGGGGAAGACTACATCA	AGGGAATCAACACCTGGAAGAACCAGGGACCAC
CCCCGCGTGTGCGGGGAAGACTACGAAA	CCCAACAGAAACTGCTGTTCCTGTGGGGACCAC
CCCCGCGTGTGCGGGGAAGACGATCGTC	GATGGTGTCCGGTCGGTCGTAGAGACGGACCAC
CCCCGCGTGTGCGGGGAAGACCCGCTGC	CGAAGGTGCTCGTGTACTGGGAGTACGGACCAC
CCCCGCGTGTGCGGGGAAGACGTGTCCC	GAACCACTACCGCGCGTCCTATGTGGGGACCAC
CCCCGCGTGTGCGGGGAAGACGATCCTG	GGGCCGACCGGCTCGCCTTGCTCCAGGGACCAC
CCCCGCGTGTGCGGGGAAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_170140047.1|2189027_2189507_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091795519.1|2192259_2193669_+|DUF2252-domain-containing-protein	unknown	unknown	gnl|CDD|313268
NZ_CP016353.1|WP_091795513.1|2187634_2189014_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl|CDD|274693
NZ_CP016353.1|WP_091795522.1|2193670_2194141_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl|CDD|182031
NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NZ_CP016353.1|WP_091798582.1|2190244_2190754_+|DUF1269-domain-containing-protein	unknown	unknown	gnl|CDD|227140
NZ_CP016353.1|WP_091795510.1|2186999_2187515_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl|CDD|378191
NZ_CP016353.1|WP_176879472.1|2172888_2173341_+|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NZ_CP016353.1|WP_091795507.1|2186279_2186786_+|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_CP016353.1|WP_170140093.1|2173497_2174583_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl|CDD|187776
NZ_CP016353.1|WP_091795529.1|2194726_2195236_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091795516.1|2189663_2190077_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091795525.1|2194130_2194730_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl|CDD|378244

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	2.1e-30	100.6	0.0
NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	3.1e-104	342.5	0.6
NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	9.5e-51	166.8	0.9
NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	1.1e-32	106.8	0.3
NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	4.2e-116	383.4	0.2
NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	1.4e-60	199.8	1.0
NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	7.8e-60	197.5	0.0
NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	1.6e-113	374.7	5.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091795513.1|2187634_2189014_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.36461e-35
NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.22015e-121
NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	2.16549e-133
NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.82596e-80
NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	5.04119e-157
NZ_CP016353.1|WP_091798582.1|2190244_2190754_+|DUF1269-domain-containing-protein	gnl|CDD|227140	COG4803, COG4803, Predicted membrane protein [Function unknown].	2.10598e-56
NZ_CP016353.1|WP_091795519.1|2192259_2193669_+|DUF2252-domain-containing-protein	gnl|CDD|313268	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252). This domain, found in various hypothetical bacterial proteins, has no known function.	5.87708e-164
NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	3.69922e-30
NZ_CP016353.1|WP_176879472.1|2172888_2173341_+|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	5.76686e-26
NZ_CP016353.1|WP_091795507.1|2186279_2186786_+|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	9.26854e-44
NZ_CP016353.1|WP_170140093.1|2173497_2174583_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	5.12229e-69
NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.38382e-51
NZ_CP016353.1|WP_091795525.1|2194130_2194730_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	3.02192e-15
NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	2.2668e-74
NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl|CDD|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	7.58097e-41

Protein sequences

>NZ_CP016353.1|WP_091795504.1|2182251_2185047_-|CRISPR-associated-helicase/endonuclease-Cas3
MSNGIAWLSPWGKTTRDQNGIVERWLPLIQHLEDSAGVARLIVDEWLPHQTRSFLERDLEGSPVTASTLVVWLAGIHDVGKASPAFAVQVPELTNRMTRHGLAMNPLQAKDSDRSKVSHGLVGHLAVRDWLTHEIGLPSRGLANQLASVVGSHHGVAPEPTQLSLVTRRPDLAGDTAWQDARRAILRHMTGVVCEPSLLTSLSESRMSKSSLVLLTAVVIMADWIASNEDFFPFEPISTADRQPWLPDRKTTAARVEKAWEQLDLPPRWLPVAPCPDIQDLFRTRFPQVSHARPVQVAMTEVARAIRGAGMVIVEAPMGVGKTEAALVAAEELAHTSGAGGVLIALPTQATTDAMFSRVREWIKALPSNDSTAISLVLAHGKASLNDEYAGLMRRGRFADVGESNDENVVVHEWLRGRKKGLLASFAVCTIDQILVGGLKSRHVMLRHLALAGKVVVIDEVHAYDVYMSQYLHRILHWLGTYGVPVVLLSATLPPARRAELLHAYGEGSGTSAVIPDESDVGYPAVLSSRGEVRTVHADAGPEVTLDRLPDDLDTLVAYLRTHLADGGCAAVVRNTVTRVQETADRLAAEFGENAITVNHSRFLACDRSRIDKDLVHRFGPSTRDNSRPSTHIVVASQVLEQSLDVDFDLLVTDLAPADLVLQRMGRLHRHLRDRPPGVRFPRCAITGVEDWAAFPVRAVTGSRRVYREHPLLRSAALFTDRSTVTLPTDIPSLVRDAYADTPLGPASWQPEMADAAKRASADAVERVNRAATYLLGDPDSPERSLVGWLRAGVGDGESQQGLAQVRDGAESLEVLVVQRDHDGGLRTADWLERGAGIQLPLDEPVPSRDARVVAACTLRLPLALSHPGVIDAVIAALEHDAHPDSFRATPMLAGQLILALDDNRQTGIRAGDQTFLLTYDLHKGLLHDRI
>NZ_CP016353.1|WP_091795501.1|2180603_2182265_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MTGSDSHPFDLLTEPWLPVRTISGETVELSLREVFGKAHDLVAISGDLATQDVALLRLLLAVLHRAVGGPRDLDHWEQLWSGKELPHARIEDYLDSHRDRFALFHPETPFFQVAGLRTAKGETAELSKLIADVPNGHPFFTTRLGSDLSLSFAEAARWVVHCQAFDPSGIKTGPVDDPRTKGGRGYPIGTGWAGRVGSVLVEGATLRDTLLLNLIASDFGDTARSPGDDLPAWERPVALPGGTRDPSGPLDLYTWQARRIRLVPDNGKVTSVLICNGEAIDTKNRHNDEPLTAWRRSAAQEKQHRLPQVYMPRQHDPSRAIWRGLQSLLPAAFENSVQNATAASGLTAVVLDWVSGLTLEGALPGDFPLRLRTVGMKYGSKDAVTEDIVDDALSLHAVLLRQDAVELVGTVLSCVSAAEQAARALGQLALNVAQAAGKSPPKPSGANPSDVSDRDRATELAYGQLDIAFRKWIPGLGPKTDPTQAQREWHHNVKQEIDPLGDDILARAPAVAITGRQVGGRLVTAAHAQSWFYLALSKAIPMAFDRGPQGSSS
>NZ_CP016353.1|WP_091795499.1|2179959_2180607_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTQVRPNKPWIGSITRDVVNKRVKGLQREALRDRPEAVAALARLRRGVGKPPGEIGDILTYTLDDQLVREHEVNRDQPTVGEFAAHHSLTLYALHQQAQNKAMHHEGPQYELGRSIRMLIADHTFPDRHPVITRFQAFSTSDSLGELVHHLRGIIQLLRGESVPLDYGLLAEKLVRWQLRGEDQVRMVWSREFYIMRRRDAKPRTDTTDTTPENS
>NZ_CP016353.1|WP_091795496.1|2178838_2179963_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MNRTIVDIHVIQTVPPSNINRDDTGSPKTAVYGGKRRARVSSQAWKRATRDDFSSFLDLSELGMRTKRVVELLTESIQKQDTDLVDQAEELATEVLSKAGIKLKAARKKDAPQEAGYLLFLSNNQIEALAELAVDAAHNGDGTVSKQDAKARADRQHSVDIALFGRMVADDADLNVDAAAQVAHALSVHEVSNEYDYYTAVDDHKRADEEEDAGAGMIGTVEFNSSTLYRYATVDVDRLRDNLGDVEATRRAVVAFARSFVTSMPTGKQNTFANRTLPDAVLILVRDTQSMNLVGAFEEVVDERESSGRIGSALTRLVGYGTDLHAAYDETPVAGWSVGIGERAEVLTGLASRTSFESATTALSELVAERLGTS
>NZ_CP016353.1|WP_091795492.1|2178143_2178842_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTVLLLRLAAPLQSWGTGSRFSRRNTDRVPSKSGIIGLLAAAEGRRRTESIADLRQLRLGVRIEQAGQIERDFQTAQSVDRSESMPLSYRFYLADAVFLVAIEGEPELLDGLNESLRRPAFPLFLGRRSCPPTGPLVLAIREGTIAEVFRNEPWQATSRVRKARRDSLVTLETVIDCEAGTDGSILVRDDPASFDPRHRKHDWRSVLPDSVAGVTNPDYAHEPMDLLPEDVT
>NZ_CP016353.1|WP_091795489.1|2177481_2178147_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MSHLTRYEFNTARRGTRWLLSSPQRLHAAVLSSFPSELTQSAEDGRILWRLDSRPHQTLLYMVSPHRPDLTHLVEETGWPRIREWETRDYDPLLTRLAPGQRWTFRLTANPAQSRRRSETASRSQRFGHVTVAQQTQWLLDRVQKHGFAVVEGKSKEPDVAVQGRHTWKFTRSGQTVTIATVVFEGTLEVTDPAALRFALINGIGPAKGYGCGLLTLAAAR
>NZ_CP016353.1|WP_091795486.1|2176513_2177479_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MPDIPGAKPVPLSQLTRAEDRLTFIYLEHSVVHRDANAITAHDARGTVHIPAATLGALLLGPGTTVSQQAMVLLAESGSTAVWVGEHGVRYYAHGRSLARSSRLLEAQAALVSDRQSRLHVARRMYAMRFPDDDTTGLSMQQLRGKEGARVRRIYRENANRTGIEWTRRDYDSADFDSGTVVNQALSAANTSLYGVVHAAIVALGCAPGLGFVHTGHVRSFVFDIADLYKADIAIPIAFDIATAQPMDVGAETRRAVRDYLRRHAFLERCVSDVKDLLRGEDEEPVEYGPDALDGPDVVMLWDYDDGEVEGGVSYPEVPDL
>NZ_CP016353.1|WP_091795484.1|2176163_2176517_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MTVIVVAACPTGLRGHLTRWLLEISPGVFVGTINARVRELVWVRVVDMVKSGRAIMVYSANNEQGLAFSVHHHNWEPVDFEGVNLMLRPNTTSDVDQSPAPRPTGWSTAARRRKFGR
>NZ_CP016353.1|WP_170140093.1|2173497_2174583_+|MFS-transporter
MTSELLPVGLLTPVGSALGVSEGTAGLMVTIPGLVAAVSAPLVTVATGRVDRRVVLAVLIGLVGAANLVSSVATSFALVLVARFLVGISVGGFWSLAGGIALRLVPPKHVPRATAVIFGGVETASVLGVPAGTFLGDLSGWRTAFAAVGVLGLISLACVVLLVPKLPARRTIGFVDLRDLFTGNRGVRKGITVTFLVITGHFLAYTFLRPILGEAGVEAKATGALLLAFGVAGICGNFLAGALIGNRLRLTVTGIGVLLGTAMVLLAVVELTTFTAGAILVLWGLGYGAVPVTVQTWIIKAAGESTEAASSLNTAAFNLSIALGALAGGLAINHVATTSVLWIGAALVMLVLPVVRSGARA
>NZ_CP016353.1|WP_176879472.1|2172888_2173341_+|carboxymuconolactone-decarboxylase-family-protein
MTTFQVPERMNFSAVAPKILKAVLALDSAARQGLDPVLVELVQIRASQLNRCAYCIDYHSTDAREAGETEERIYQLSAWQEAGVYTLRERAALALTEHVTLLPGGVPDEVYDRAAEHFDEAELARLIAVIFTVNTWNRMNVTTRKTPGTP
>NZ_CP016353.1|WP_091795507.1|2186279_2186786_+|DinB-family-protein
MNEDPRTHPPREGDERASLTGFLDFQRQTLAVKCAGLNAEQLRRKTVPPSDMSLIGLVRHMAEIERGWFEKVMNGEQLDTYWGMRPDGDYAEFDVDDAEPDEAFAVWNKACARSSEIVAAIESLDTVRHHGDLGYSLRWVLIHMIEEYARHNGHADLLRERIDGETGE
>NZ_CP016353.1|WP_091795510.1|2186999_2187515_+|hypothetical-protein
MARASRDTATRESGSGRRRASGIYGAIVAAAVLTAAGEALSTAALAVAVVATLLVYWLAEEYAVLLGQHAEAGKLPSAGRIRAELAATWPMVTASYGPLVALLLAWLAGASPVTAANVGLVAAVLLLVFHAWSAGMAARLRGVPLIAVTTVAALLGVLMVVLKNFVLLHLH
>NZ_CP016353.1|WP_091795513.1|2187634_2189014_+|MFS-transporter
MSERAGAGTAVLVPLALAQFICSFAGSAMNVMINDISTDLDTSVHGVQLVITAFLLVMAALMIPGGKLTDLLGRKRCFVAGLALYGAGALLSALAPGIVVLFLGNSILEGIGTALLIPPVYILTTLLFTDLASRAKAFGAIMAMGGVGAAAGPLIGGLITSGIGWRATFGFQVLIIIVIIVLGRKITDPLPAETGRSFDVGGTVLSAVGLVTLVLGILAADNNIWLTLALLAAGSLVLAGFFARVRVREHAGKAVLVSTSMFKNKVVNLGLVTQNLQWLMLLGSSFVVATYLQVVRHYNAIETGVIFTPATIGLLGSSLLAERLAKRREQRSLIMAGFVLTVAGMGLLLAFAGLFTSPWPFAPGLFFIGLGLGLMLTPSVNVVQSGFGDEQQGEISGVSRCVSNLGSSLGTAIAGTILVSGLTSHSYAAAMIVLAVAGVGGLGAAAFLPRERAVAAGPA
>NZ_CP016353.1|WP_170140047.1|2189027_2189507_-|hypothetical-protein
MTQHTHHDTGNRTGPATANQRPQPARELPITRTSWVNWIWFAGAMMILLGMFNVIQGLVALLNDQYYVVGPSGLLVFDITGWGWVQLGLGAAAVTAGLCLFTGAMWARVVAVGLAAVNAVAQMAFLAANPVWCTIVIALDILVIWAVVVHGKEVKVEQW
>NZ_CP016353.1|WP_091795516.1|2189663_2190077_-|hypothetical-protein
MSDNAKPQRATGWTGWVAFCGMMLVLLGSFHAIEGLVAVFDSAYSDTGSPGLVARLGYPAWGWLQAGLGAVAVLTGVGVLSGNSAARVGGVVFAAASAVTHLLFSSASTAGTAIVVAIDVIVIYALVAHGREITLRD
>NZ_CP016353.1|WP_091798582.1|2190244_2190754_+|DUF1269-domain-containing-protein
MGTLTVWKFDSASGAEQALHLLTRLQKEQLIRINDAAYVSWPEGRKKPKTKDLGKLTGSGALGGGFWGFLFGLLFFVPLLGTAVGAAFGALAGSLAHAGIDEDFVAEVRRQVVPGTSALFVVSSEAVADRVLGSFRETGASLITTNLSHEQEERLRQAFAEAEDESQVV
>NZ_CP016353.1|WP_091795519.1|2192259_2193669_+|DUF2252-domain-containing-protein
MSVRTGTAVVARSASRAERAAEGRAARAETPRSSHAAFERGLGRTPLELLAAQDRARVPSLAGIRYERMAASPFAYFRGAALPMAHDLALTPATGFTVQACGDAHLANFGLFASPERRLVFDINDFDETAKGPWEWDVKRLAASVEIAGRGNGFSTAERTRAVLATVGAYRQAMRDFAGRTALEVWYAIAEVDAVRALAAPKLSAAGKKRLDRTVVKARSHDQLGSLARFTTAEGGSLRIEPDPPRVVPVEGQAEDGGDAAFARIERVLAAYRETLEPERRVLLDRYSLVDVARMVVGVGSVGTRCWMLLLLGHDEADPLFLQAKEAGPSVLEQFTGRGEYSNHGQRVIVGQRLMQAVSDIFLGWVAVTGFDGKDRDFYIRQLRDGKGSVPVESMVPDGLLAYGRLCGWTLARAHARSGDAVAIAAYLGSGPVFDCAVREFASACAEMNDHDHAALCRAAGSGTIREGH
>NZ_CP016353.1|WP_091795522.1|2193670_2194141_+|hypothetical-protein
MTTTEQLLLPREDADPVIADVVIGVADVLAESAGRLVLVLRPLTGGLLAPERWPRFVRELAGRGVRRRRQVGEAALRGYRFVTPVLVTDALDRLDLPGIVREVLAEIDLPEIIRTSTGSVASESVRDVRIRLVAADDAVSRRFGGRRDTAARGHDE
>NZ_CP016353.1|WP_091795525.1|2194130_2194730_+|RDD-family-protein
MTSERRAHRQSWLSGLPQEARAFQGKRAGFVSRGVAAIVDGLVVVVLLGMLYLAFAALGFLIDPTGFAFPVPGREALVLAWFVLAVLYLSVCWAGTARTVGDQLLGLRVLGARGFRLRWGQACVRALACVLFPWGLLWILAGRHRRSLQDLLLRTVVIYDWGPRLPRTSPATREAKDDGERKARPDGEGNEDEEEGEDS
>NZ_CP016353.1|WP_091795529.1|2194726_2195236_+|hypothetical-protein
MTGVLSRSGRGALARVAAIAAIAAVSAGCAQDEGGGTRTPPSSASTSATSATTSPPSSGPVEQECAALLTSGRDLLDTVTRFAGGQATGDEVRAAATDLRTAIDRASGVIGAEAGAALNTAKTALGELETALTAQPPDLQSARAAGGEALTGVRDAATLCESGQSTTSR

Crispr_ID: NZ_CP016353_6

• CRISPR_ID: NZ_CP016353_6
• CRISPR_location: 2665706-2666407
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 11 spacers

Consensus repeat of NZ_CP016353_6

Consensus_repeat	Method
GGAACACCCCCGCTCGCGCGGGGAAGAC	CRISPRCasFinder
GGAACACCCCCGCTCGCGCGGGGAAGAC	CRT
GAACACCCCCGCTCGCGCGGGGAAGAC	PILER-CR

spacers of NZ_CP016353_6

>6.1|2665734|33|NZ_CP016353|CRISPRCasFinder,CRT
CGAGATACGCCGTGGCCGGTGTGGTTGCTGTGG
>6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT
GCTCGTCGGATGTCGGCCAGCTCGGCGCGAGCGG
>6.3|2665857|33|NZ_CP016353|CRISPRCasFinder,CRT
CTAATGATCAGGTGAACAAGCTTCGCGAGCACC
>6.4|2665918|34|NZ_CP016353|CRISPRCasFinder,CRT
ACGGGGCAAGGAAGGGCCGAGCTGACCCGGACGG
>6.5|2665980|34|NZ_CP016353|CRISPRCasFinder,CRT
AGCCCCGGTTCGGTGGTAGACCACCGACCTGACC
>6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT
GCTGGCTGACGGTCGATGAGGCGACGATCAACG
>6.7|2666103|33|NZ_CP016353|CRISPRCasFinder,CRT
CCGCGTTTGAACCTCGCATCATAGTCATTCCAG
>6.8|2666164|33|NZ_CP016353|CRISPRCasFinder,CRT
TGCCGGACACCAGCACCACACCGGTACCGCCGG
>6.9|2666225|33|NZ_CP016353|CRISPRCasFinder,CRT
GGTGTCTCTCTCGGTGCTCACCGGTCCTCCAGC
>6.10|2666286|33|NZ_CP016353|CRISPRCasFinder,CRT
TCCCACATCCGCCGATGCGACCTCACAGCCTTC
>6.11|2666347|33|NZ_CP016353|CRISPRCasFinder,CRT
ACCCGATGACCGGTGTACCGCCGTCGTATCGGA
>6.12|2665857|34|NZ_CP016353|PILER-CR
CTAATGATCAGGTGAACAAGCTTCGCGAGCACCG
>6.13|2665918|40|NZ_CP016353|PILER-CR
ACGGGGCAAGGAAGGGCCGAGCTGACCCGGACGGGAACAC
>6.14|2665985|35|NZ_CP016353|PILER-CR
AGCCCCGGTTCGGTGGTAGACCACCGACCTGACCG
>6.15|2666047|34|NZ_CP016353|PILER-CR
GCTGGCTGACGGTCGATGAGGCGACGATCAACGG
>6.16|2666108|34|NZ_CP016353|PILER-CR
CCGCGTTTGAACCTCGCATCATAGTCATTCCAGG
>6.17|2666169|34|NZ_CP016353|PILER-CR
TGCCGGACACCAGCACCACACCGGTACCGCCGGG
>6.18|2666230|34|NZ_CP016353|PILER-CR
GGTGTCTCTCTCGGTGCTCACCGGTCCTCCAGCG
>6.19|2666291|34|NZ_CP016353|PILER-CR
TCCCACATCCGCCGATGCGACCTCACAGCCTTCG
>6.20|2666352|34|NZ_CP016353|PILER-CR
ACCCGATGACCGGTGTACCGCCGTCGTATCGGAC

CRISPR arrays and Neighbor proteins around NZ_CP016353_6

CRISPR arrays

The CRISPR arrays of NZ_CP016353_6

>merge|NZ_CP016353|6|2665706-2666407|CRISPRCasFinder,CRT,PILER-CR
GGGATATCCCCGCTTATGCGGGGAGGACCGAGATACGCCGTGGCCGGTGTGGTTGCTGTGGGGAAGACCTCCGCTCGCGCGGGGAAGACGCTCGTCGGATGTCGGCCAGCTCGGCGCGAGCGGGGAACACCCCCGCTCGCGCGGGGAAGACCTAATGATCAGGTGAACAAGCTTCGCGAGCACCGGAACACCCCCGCTCGCGCGGGGAAGACACGGGGCAAGGAAGGGCCGAGCTGACCCGGACGGGAACACCCCCCGCTCGCGCGGGGAAGACAGCCCCGGTTCGGTGGTAGACCACCGACCTGACCGGAACACCCCCGCTCGCGCGGGGAAGACGCTGGCTGACGGTCGATGAGGCGACGATCAACGGGAACACCCCCGCTCGCGCGGGGAAGACCCGCGTTTGAACCTCGCATCATAGTCATTCCAGGGAACACCCCCGCTCGCGCGGGGAAGACTGCCGGACACCAGCACCACACCGGTACCGCCGGGGAACACCCCCGCTCGCGCGGGGAAGACGGTGTCTCTCTCGGTGCTCACCGGTCCTCCAGCGGAACACCCCCGCTCGCGCGGGGAAGACTCCCACATCCGCCGATGCGACCTCACAGCCTTCGGAACACCCCCGCTCGCGCGGGGAAGACACCCGATGACCGGTGTACCGCCGTCGTATCGGACGAACACCCCCGCTCGCGCGGGGAAGAC

>NZ_CP016353|6|5|2665706-2666407|CRISPRCasFinder
GGGATATCCCCGCTTATGCGGGGAGGAC	CGAGATACGCCGTGGCCGGTGTGGTTGCTGTGG
GGAAGACCTCCGCTCGCGCGGGGAAGAC	GCTCGTCGGATGTCGGCCAGCTCGGCGCGAGCGG
GGAACACCCCCGCTCGCGCGGGGAAGAC	CTAATGATCAGGTGAACAAGCTTCGCGAGCACC
GGAACACCCCCGCTCGCGCGGGGAAGAC	ACGGGGCAAGGAAGGGCCGAGCTGACCCGGACGG
GAACACCCCCCGCTCGCGCGGGGAAGAC	AGCCCCGGTTCGGTGGTAGACCACCGACCTGACC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GCTGGCTGACGGTCGATGAGGCGACGATCAACG
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCGCGTTTGAACCTCGCATCATAGTCATTCCAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	TGCCGGACACCAGCACCACACCGGTACCGCCGG
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGTGTCTCTCTCGGTGCTCACCGGTCCTCCAGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	TCCCACATCCGCCGATGCGACCTCACAGCCTTC
GGAACACCCCCGCTCGCGCGGGGAAGAC	ACCCGATGACCGGTGTACCGCCGTCGTATCGGA
CGAACACCCCCGCTCGCGCGGGGAAGAC

>NZ_CP016353|6|3|2665706-2666407|CRT
GGGATATCCCCGCTTATGCGGGGAGGAC	CGAGATACGCCGTGGCCGGTGTGGTTGCTGTGG
GGAAGACCTCCGCTCGCGCGGGGAAGAC	GCTCGTCGGATGTCGGCCAGCTCGGCGCGAGCGG
GGAACACCCCCGCTCGCGCGGGGAAGAC	CTAATGATCAGGTGAACAAGCTTCGCGAGCACC
GGAACACCCCCGCTCGCGCGGGGAAGAC	ACGGGGCAAGGAAGGGCCGAGCTGACCCGGACGG
GAACACCCCCCGCTCGCGCGGGGAAGAC	AGCCCCGGTTCGGTGGTAGACCACCGACCTGACC
GGAACACCCCCGCTCGCGCGGGGAAGAC	GCTGGCTGACGGTCGATGAGGCGACGATCAACG
GGAACACCCCCGCTCGCGCGGGGAAGAC	CCGCGTTTGAACCTCGCATCATAGTCATTCCAG
GGAACACCCCCGCTCGCGCGGGGAAGAC	TGCCGGACACCAGCACCACACCGGTACCGCCGG
GGAACACCCCCGCTCGCGCGGGGAAGAC	GGTGTCTCTCTCGGTGCTCACCGGTCCTCCAGC
GGAACACCCCCGCTCGCGCGGGGAAGAC	TCCCACATCCGCCGATGCGACCTCACAGCCTTC
GGAACACCCCCGCTCGCGCGGGGAAGAC	ACCCGATGACCGGTGTACCGCCGTCGTATCGGA
CGAACACCCCCGCTCGCGCGGGGAAGAC

>NZ_CP016353|6|4|2665830-2666407|PILER-CR
GAACACCCCCGCTCGCGCGGGGAAGAC	CTAATGATCAGGTGAACAAGCTTCGCGAGCACCG
GAACACCCCCGCTCGCGCGGGGAAGAC	ACGGGGCAAGGAAGGGCCGAGCTGACCCGGACGGGAACAC
CCCCCGCTCGCGCGGGGAAGACAGCCC	CGGTTCGGTGGTAGACCACCGACCTGACCGGAACA
CCCCCGCTCGCGCGGGGAAGACGCTGG	CTGACGGTCGATGAGGCGACGATCAACGGGAACA
CCCCCGCTCGCGCGGGGAAGACCCGCG	TTTGAACCTCGCATCATAGTCATTCCAGGGAACA
CCCCCGCTCGCGCGGGGAAGACTGCCG	GACACCAGCACCACACCGGTACCGCCGGGGAACA
CCCCCGCTCGCGCGGGGAAGACGGTGT	CTCTCTCGGTGCTCACCGGTCCTCCAGCGGAACA
CCCCCGCTCGCGCGGGGAAGACTCCCA	CATCCGCCGATGCGACCTCACAGCCTTCGGAACA
CCCCCGCTCGCGCGGGGAAGACACCCG	ATGACCGGTGTACCGCCGTCGTATCGGACGAACA
CCCCCGCTCGCGCGGGGAAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_170140022.1|2658301_2659276_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256
NZ_CP016353.1|WP_091797234.1|2670686_2674316_+|methionine-synthase	unknown	unknown	gnl|CDD|236539
NZ_CP016353.1|WP_091797242.1|2676439_2677390_+|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|168796
NZ_CP016353.1|WP_091797240.1|2675553_2676447_+|3-keto-5-aminohexanoate-cleavage-protein	unknown	unknown	gnl|CDD|377562
NZ_CP016353.1|WP_091797225.1|2666637_2667288_+|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|188483
NZ_CP016353.1|WP_091798810.1|2667308_2667827_-|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl|CDD|334450
NZ_CP016353.1|WP_091797245.1|2677386_2677824_+|thioesterase-family-protein	unknown	unknown	gnl|CDD|236044
NZ_CP016353.1|WP_091797248.1|2677855_2679412_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173868
NZ_CP016353.1|WP_091797231.1|2668757_2670488_+|FAD-binding-protein	unknown	unknown	gnl|CDD|235758
NZ_CP016353.1|WP_091797228.1|2667994_2668741_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|223774
NZ_CP016353.1|WP_091797213.1|2660061_2660709_+|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|376808
NZ_CP016353.1|WP_091798807.1|2665225_2665669_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|226489
NZ_CP016353.1|WP_091797222.1|2663891_2665106_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|367570
NZ_CP016353.1|WP_091797217.1|2661832_2662048_-|lipid-A-biosynthesis-lauroyl-acyltransferase	unknown	unknown	unknown
NZ_CP016353.1|WP_091797215.1|2660812_2661736_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293840
NZ_CP016353.1|WP_170140023.1|2657483_2658305_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|130314
NZ_CP016353.1|WP_091797237.1|2674699_2675557_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379409
NZ_CP016353.1|WP_091797219.1|2662574_2663603_+|TerC/Alx-family-metal-homeostasis-membrane-protein	unknown	unknown	gnl|CDD|274743
NZ_CP016353.1|WP_091798804.1|2659391_2660009_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|182632
NZ_CP016353.1|WP_091797211.1|2656426_2657107_+|TIGR03086-family-protein	unknown	unknown	gnl|CDD|274424

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_170140022.1|2658301_2659276_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	9.51597e-111
NZ_CP016353.1|WP_091797234.1|2670686_2674316_+|methionine-synthase	gnl|CDD|236539	PRK09490, metH, B12-dependent methionine synthase; Provisional.	0
NZ_CP016353.1|WP_091797242.1|2676439_2677390_+|3-hydroxybutyryl-CoA-dehydrogenase	gnl|CDD|168796	PRK07066, PRK07066, L-carnitine dehydrogenase.	1.51711e-108
NZ_CP016353.1|WP_091797240.1|2675553_2676447_+|3-keto-5-aminohexanoate-cleavage-protein	gnl|CDD|377562	pfam05853, BKACE, beta-keto acid cleavage enzyme. BKACE, beta-keto acid cleavage enzyme plays, a role in lysine degradation. In certain instances it catalyzes the conversion of 3-keto-5-aminohexanoate and acetyl-CoA into acetoacetate and 3-aminobutyryl-CoA. The family is found to have at least 14 slightly different potential new enzymatic activities, all of which can therefore be designated as beta-keto acid cleavage enzymes.	4.37132e-128
NZ_CP016353.1|WP_091797225.1|2666637_2667288_+|TetR-family-transcriptional-regulator	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	1.81328e-16
NZ_CP016353.1|WP_091798810.1|2667308_2667827_-|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl|CDD|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	2.66598e-08
NZ_CP016353.1|WP_091797245.1|2677386_2677824_+|thioesterase-family-protein	gnl|CDD|236044	PRK07531, PRK07531, carnitine 3-dehydrogenase.	6.66729e-34
NZ_CP016353.1|WP_091797248.1|2677855_2679412_+|ABC-transporter-substrate-binding-protein	gnl|CDD|173868	cd08503, PBP2_NikA_DppA_OppA_like_17, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP016353.1|WP_091797231.1|2668757_2670488_+|FAD-binding-protein	gnl|CDD|235758	PRK06263, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	2.85268e-165
NZ_CP016353.1|WP_091797228.1|2667994_2668741_+|SDR-family-oxidoreductase	gnl|CDD|223774	COG0702, COG0702, Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	8.62415e-17
NZ_CP016353.1|WP_091797213.1|2660061_2660709_+|NAD(P)H-dependent-oxidoreductase	gnl|CDD|376808	pfam02525, Flavodoxin_2, Flavodoxin-like fold. This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.	2.62529e-38
NZ_CP016353.1|WP_091798807.1|2665225_2665669_+|GNAT-family-N-acetyltransferase	gnl|CDD|226489	COG3981, COG3981, Predicted acetyltransferase [General function prediction only].	1.50677e-40
NZ_CP016353.1|WP_091797222.1|2663891_2665106_+|alpha/beta-hydrolase	gnl|CDD|367570	pfam03583, LIP, Secretory lipase. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.	2.09005e-10
NZ_CP016353.1|WP_091797215.1|2660812_2661736_+|MBL-fold-metallo-hydrolase	gnl|CDD|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.42235e-68
NZ_CP016353.1|WP_170140023.1|2657483_2658305_-|ABC-transporter-permease	gnl|CDD|130314	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein. This model describes daunorubicin resistance ABC transporter, membrane associated protein in bacteria and archaea. The protein associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	9.25282e-17
NZ_CP016353.1|WP_091797237.1|2674699_2675557_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|379409	pfam13977, TetR_C_6, BetI-type transcriptional repressor, C-terminal. This family comprises the C-terminal portion of proteins that belong to the TetR family of transcriptional regulators. The C-terminus represents the regulatory region, and does not include the DNA binding helix-turn-helix domain. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. One of the target proteins is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	4.26365e-24
NZ_CP016353.1|WP_091797219.1|2662574_2663603_+|TerC/Alx-family-metal-homeostasis-membrane-protein	gnl|CDD|274743	TIGR03718, R_switched_Alx, integral membrane protein, TerC family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.	9.09679e-117
NZ_CP016353.1|WP_091798804.1|2659391_2660009_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|182632	PRK10668, PRK10668, DNA-binding transcriptional repressor AcrR; Provisional.	5.34069e-10
NZ_CP016353.1|WP_091797211.1|2656426_2657107_+|TIGR03086-family-protein	gnl|CDD|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	2.16465e-33

Protein sequences

>NZ_CP016353.1|WP_091798807.1|2665225_2665669_+|GNAT-family-N-acetyltransferase
MLDEGFEFGWGLREELEWSAYLRLLADQRDERGRKEGTVPATLLVAEVGGRIVGRTSVRHTLDDALLRVGGHIGYAVLPPYRRRGYATEILRQSVIVARSLGVDRILVTCDEDNAASATVIEANGGRWENTLPAGPGRPGKRRYWIG
>NZ_CP016353.1|WP_091797222.1|2663891_2665106_+|alpha/beta-hydrolase
MRTGRRAWFAAIAVAAFTMAGACDGSDGEGQDAVGEAEAAEAANALPRGDFYAAEPTPDQPGTVVRSESFADWSLEDGMRGTRMIYDSRSARGEPVVTSAAVVTPDGEPPRGGWPVIAWAHGTSGVAPQCAPTLMKDLYYGEVIKEYVKRGYAVVATDYSGLGAGKGHEYITMQANANDVRYSVAAARQAVDGLAERWIAVGHSQGGQAAWGAARQQAAEPVGELLGAVALAPATSLDRSGAAIRNAAGSAAYLPYIGYTLAEQYPGFKPEDILTEAGMRHYDRYVKEGCLPLAVALTGDATPAQFLKPGWLGNPSVREFIERNRYANEKTAVPLFVASGAKDVSVAPATVAETVAEQCAHETAVEYTEYPGTHDELIGESSADVMRWIADRFAGVRPPPGNCG
>NZ_CP016353.1|WP_091797219.1|2662574_2663603_+|TerC/Alx-family-metal-homeostasis-membrane-protein
MSAPSAVAAGPAQSVGSVGLWLISIAVLVALLTADFLVTRRPHEVQLKEAVGWSLFYLALPVVFGLWLWLDAGTPQAVEFFTGFVVEKSLSVDNLFVFMLLLTAFAVPPAVQQRVLLYGIAGALVLRGIFIAAGAALLAAGTWAFLVFGLILFASALKILHEVMSKKETEKDVSQMRSVRLLRKLMPVTDDYRGTKLTVRENGRRALTPLAVVVVAVFAADIVFAVDSVPAVYGITDDPYLVFATNAFALLGLRALYFVLRSVLAKLVHLNHGLAVILGFIGLKLVLHWAHGIWPAVPEIPTALSLGVIIGVLGVVTLTSMRARRRTTAAGTSGEDAATRQG
>NZ_CP016353.1|WP_091797217.1|2661832_2662048_-|lipid-A-biosynthesis-lauroyl-acyltransferase
MELTFLWKDAASGDGSGDGGGCPALYRTEGGYVVQGVKLDPATRSQLRQLADDEDGVFVPANVLERLKDLT
>NZ_CP016353.1|WP_091797215.1|2660812_2661736_+|MBL-fold-metallo-hydrolase
MGPDTAELKEIVDGVYAYVQPDGTWWVNNAGVVTGEGGTLVVDTCATARRTRRFLGLAADVTGDAAPRWAVNTHQHGDHAYGNSLLPASTVLIGHEAMRAALAVDPLIDACPPVWSPVPDWGQVTRRLPDVVMRSDLVLYTGGRRLELRHPGYEAHTPGDVIVWLPEEKVLFAGDLVFNGLTPMMGMGSCAGGLRALAWLESLRPDHVIPGHGPVFGGADVEELFGTIAAYYRLVLETAEAGRRDGLSPLDAARRCDLGEFAAWPDSERLVLNLHREYALAEGKGPDLAAALADAVAYNGGPMRTSV
>NZ_CP016353.1|WP_091797213.1|2660061_2660709_+|NAD(P)H-dependent-oxidoreductase
MNEPTITGPKILAVVAHPDRQSLTWKITERVGSAITEAGGRFSTLDLYADDFSPAYDNVDRQHFRAAEGLPGDVVAHQALIDEADALVVIFPVFWWSMPGVLKGWFDRVFARDWAYDIAEDGSDHGRLGDRSMHSIAIAGAGQGVYERHGYRDALHAQLTHGIFEYCGVRDPGSHLIFGSENPDKIDEHFAQAGLIGEELVAAANLARTAVAATT
>NZ_CP016353.1|WP_091798804.1|2659391_2660009_+|TetR/AcrR-family-transcriptional-regulator
MTHDDSTDRTTPVATERGSGRRLGRAERREQIIDAATRAFAEAGGFAQAGLADVASAAGVTRMILYRHFDSKTELYRAAIDRAAERLHAAAVVDGEMDDESVARVFRWARSEPDAFRLLFRHAAREPEFRDDIDELKAAMIARVRPYLEETITGEPWQAWAAQFSTLVIIEAVMAWLDAGAPGGDDAIHRILRSVDSAIESIGSG
>NZ_CP016353.1|WP_170140022.1|2658301_2659276_-|ATP-binding-cassette-domain-containing-protein
MTKTSTRPGNRGEPAVLATGLTKRFGSTRALDGVDLEVREGTVHGLLGPNGAGKSTVVRILSTLLRPDGGTARVAGHDVRGDPSGVRYRIGLAGQRTAVDDMLSGRENLEMFARFYRFGRAAAKRRTNELLEQFDLGDAADRKPKGYSGGMRRRLDLAISFIMAPPVLFLDEPTTGMDPGHRMDVWHAVRTLVTNGTTVVLTTHFLDEADNLADSISVIDHGRVITSGTPDELKSALRGDRIDVLVGESSDLTRVSLLLAGVTDSAPDIARDACKISVPARDRVATLARIARALDDEKVAVRDIALRRPTLDEVFVRLTGKDNA
>NZ_CP016353.1|WP_170140023.1|2657483_2658305_-|ABC-transporter-permease
MTTIVIPCNRTEKLRAALADSATMTRRNLTYWWRSPEELLGSLAFPLISVLLFGYVFGSAMTVPGGGDYLDYLLPGLFGMTMVFGLVITISAVVTDRERGVTDRFMAMPISSAAILVGRSLSDMTRASADLVVLLGCGVLVGWRWQGSVLEAAAAVGLLLLLRFALVWVGIYIGLVLRSPDSSAMLYPLVLPFAMVANTFVAPALMPGWLGVVAEANPMSSTVAATRELFGTSASTGQTWMADHPFLLAICWPVLLLAIFVPLAVHRYRKSRH
>NZ_CP016353.1|WP_091797211.1|2656426_2657107_+|TIGR03086-family-protein
MLTNLPDNLPELDAGAVRAGLDVVARVTSADLRLPTPCAEWSLGDLLAHMTAQHHGFAAAAEGEGADPSAWRLRPLGDDPVSDYLTSANKVLAAFARPGVLERPFALPEIHPDTVPGRLAVSFHFVDYVVHGWDVAVSLGLPFDPGANEAEAALRIALQVPGGDSRLEPGAAFGPVVPAQAEASTMDRVLAALGRSPQWTPATAGRAGAEGSWSSRPRRRVPHSGR
>NZ_CP016353.1|WP_091797225.1|2666637_2667288_+|TetR-family-transcriptional-regulator
MVSRTSESSGGQREQALGRRERKKLATRAAVQEAAVRLAVRFGVENVTVEQIAAEADIALRTFFNYFPSKEHALVAFTASGADALVEAFRARPATESVLDAIRGSVLVVMSENISASRTHIDALRLISEAPSLWPHQLAILTGYEKALASAIAERGEPDGLYASVCAAASIAALRVVVARCLARSGSGAFSLEEFRSEFDKALAELGAGLDRPPGT
>NZ_CP016353.1|WP_091798810.1|2667308_2667827_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MKEPTSTTNLDRYGSAQLPWSRARDIMASDTPKEMLTFFVSTVRPDGRPHSAGVGAVWVDDALYFTGGPGARRSRNLAANAACTVSVSLRGIDLVLEGEARRVTDSATLERVAAVYRDGGRPATVRGDAFTAPFSAPSAGPPPWHLYRLTLDTAIGVASAEPHGASRWDFAY
>NZ_CP016353.1|WP_091797228.1|2667994_2668741_+|SDR-family-oxidoreductase
MKIVVIGGTGLIGSKVVALLGSQGHDAVAASPATGVNTITREGVADALRGADVLVDVSNSPSFADADVLAFFGTSTRTLIEEAGGAGVGHYVALTVVGTRRLAASGYFRAKVDQENLIAASGLPYSLVHATQFFEFAGGIAEGATLDGAVRLSGASVRPIAAGDVAAMVVDVAVKPRGGALEVAGPEVLGLDEWVRTVLAARGDTRKVVVDPEAAYFGARLRQDSLLPGPDAEIAPTRLADWLALDQR
>NZ_CP016353.1|WP_091797231.1|2668757_2670488_+|FAD-binding-protein
MNHPEKQLATSVLVIGTGGAGLRAAIELAERGVDVLVLGKRPKSDAHTTLAAGGINAALSTMDKEDTWAQHAADTIKESYLLAHPDIVRVVTENGPRGIADLERWGMPFAREDDGRISQRFFGAHTHRRTAFAGDYTGLEIQRTLVNRAALLNVPVLDTCYVTRILVKDNAVFGAYGFDIGTGQRYVIHADAVVLAAGGHTRIWRRTSSRRDENTGDAFRLAVLAGGRIRDPELVQFHPSGLIEPENAAGTLVSEAARGEGGILRNADGERFMARYDPDRLELSTRDRVALAAYTEIKEGRGTPRGGVWLDVSHLPRETIMNRLPRVYQTLLELQMLDITSDPVEVAPTAHYSMGGVWVRPEDHGTGVDGLYAIGEASSGLHGANRLGGNSLIELLVYGRIVGEEAARYSARLPAQRRSKEALALARAEVDELLAADGPENVRALQRALRDTMTEHAGVVRDETGLRAGLAELDEIERRMAGLGVHPDRAGYTDLAHAFDLKASALAARATMEAALERRETRGCHNRADYPELDPALRVNLVWSGPGKVEREELPPVPDEIAALMREVSSEGKLVE
>NZ_CP016353.1|WP_091797234.1|2670686_2674316_+|methionine-synthase
MDTISALRRILDERVAVLDGAWGTSLQNAGLTPADYRGDGLVGADHPQDVTGDPDLLNLTRPDLILDVHRGYFAAGADITTTNTFTATSIGQADYGLQHLVREMNLRGAALARQAADEAGGGFVAGSIGPLNVTLSLSPNVDEPAYRAVTFDDVRDSYAEQIAALAEGGVDLLLVETIFDTLNAKAAIAAAREVAPHLPLWISVTIVDLSGRTLSGQTVEAFWNAIEHADPLIVGVNCSLGAAEMRPHVEQLAKLAGTYLACHPNAGLPNAFGGYDQTPEETAGLLAEFATSGMVNVVGGCCGTGPEHIAAISAAVKGTAPRAVPSPSTLARFSGLEPFEIGPDTGFVMIGERTNVTGSARFRRLVESGAYQDAVAVALDQVRGGANVLDVNMDADLLDSEQAMTTFLNLIATEPEAARIPVMIDSSRWSVLEAGLKCVQGKGIVNSISLKEGEEQFLRQARRIRDYGAGVVVMAFDEQGQADTTERKVEICGRAYDLLTGEADFPPEDIVFDPNVLAVATGISEHNGYAKAFIDALPLIKRRCPGARTSGGISNLSFSFRGNNVVREAMHSAFLLYAIRAGLDMGIVNAGQLTVYEDIPADLLELVEDVLFDRRDDATDRLVSFAETVNDSGRGRASTVDLSWRDAPVEQRLRHALVHGIVDYIEEDTEAARLSRSRPLDVIEGPLMDGMKTVGDLFGAGKMFLPQVVKSARVMKRSVAYLEPFMEEEKERSRQAGDVEQDRGQGTIVLATVKGDVHDIGKNIVGVVLGCNNYQVIDLGVMVPASVLLDTAIAENADAVGVSGLITPSLDEMVGVAAEMQRRGLKIPLMIGGATTSKQHTAVRIAPAYEQTTVHVLDASRVVGVVSDLLDPGRSAALAETTRADQQRLREQHEKRQHRPMLALEKARANPEKVPFDDVPVPSFTGARIVEPGLAAVREMIDWQFLFLAWEVKGKYPAILDQPVARELFDDANTMLDQILADESLQARGAYGFWEAHSEGDDILLGNGVRFPMLRQQTVKPSGRANRCLADYIAPAGDHRDYLGGFAVAIHGAQELAAHYEKQHDDYKAIMVKALADRLAEAFAELIHLRARREWFEPEARPSLEDLHAERFRGIRPALGYPASPDHSQKRELFDLLGAEDIGLGLTESFAMTPAASVSGLIFAHPASRYFTVGRLGRDQVEDYALRRGVARVEVEKWLRPNLDYTPDA
>NZ_CP016353.1|WP_091797237.1|2674699_2675557_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MAETDYLRTRVRSLIPEKPGAQREFAKAIGLDETKLSKSLKGTRRFSSHELVHIAEHAGVTVNWLLNGSDEAATVTAIPVARPAGEIAEWRQPERRRRILETAWELIATRGYHHVRIADIASACGTSTATIHYYFPTREEVLNEALRRNVKLAFDRQVAELHTVGSAHERLVRLVELQLPTAGLLRDEWSVWLQVWNETALNPAMRELYWDSYDRWFNTIAMTIRNGQEQGVFRERDSREITTQLTALIDGLGIQVLTGKPGSSVDSMREHLRDFIDRNIVKGGQ
>NZ_CP016353.1|WP_091797240.1|2675553_2676447_+|3-keto-5-aminohexanoate-cleavage-protein
MNSEVIITCALTGAGDTAGKSEHVPVSPEQIAASAVEAANAGAAVVHIHVRDVETGKGSRDVALYRDVVRRVADSGVDVVVNLTAGMGGDLVLDDEDPLKPVDGTDLVNANDRLPHVEELLPDICTLDCGSLNFGEGHQLYVSTPDMLRAGAKRIQELGVKPELEIFDTGQLWFATKMIEEGIIDPPPLFQLCMGIPYGAPANPELLQTMVNMLPDGSQWASFSIGRDQLPWVAHSALLGGHVRVGLEDNLYLSKGVKATNGQLVERAVGIVEGLGAKIASAEDARRILNLRGARGA
>NZ_CP016353.1|WP_091797242.1|2676439_2677390_+|3-hydroxybutyryl-CoA-dehydrogenase
MPEPDEVTTVACIGAGVIGGGWVAHFLAKGFRVRAWDPAPDAERRLGRLVEAAWPALTELGLAEGASRDNLTVLPTLAEAVEGAEFVQESAPEDLAVKRTLLADIAAAAPEGVVIASSTSGYGMSEMQTEAATPGRLVVGHPFNPPYLIPLVEVAGGTRTEAWAVDWASRFYRQVGKTVITMDNELPGFIANRLQEALWREALHMVANGEATVEQIDTAITDGPGLRWPVHGPCLTFHLAGGEGGMAHMLDHFGPSLKAPWTRLEAPELTRRLRDDMVDGCETEAGERSIADLVAERDRAIIAVQRAVRASRETTS
>NZ_CP016353.1|WP_091797245.1|2677386_2677824_+|thioesterase-family-protein
MSEPLEYHDTVRDEWIDYNGHLSEPFYVMVFGFATTNLMDHVGLDERYRAETGRSLYTVEAHVRYLREVGRDAALHVTTFVLSVGEKKVRLCHELRVDGELVATEELLAIHVAGARAAPLAEDIADRLRRHRLPAPGYAGRAISS
>NZ_CP016353.1|WP_091797248.1|2677855_2679412_+|ABC-transporter-substrate-binding-protein
MSFDKHISRRKFLVGSAVLAGSVPLLSACGGRSSAVTVPTGPPRRGGTLRVGITGGGASDTLDPHIPATSPDIARVRNLYEPLLYRDHEYRIEMLVAESLTSSPDAKTWTATLRQGIKFHDGRPVTPDDVIATFRRIMDPDDPKSGAASLTMLGEVVAKGDRQVEFRLTEPSTVFDDYLAQYHLGIVPADFSVDRPIGTGPFRAKDFTAGLQSAFVRNEHYWRSGEPYLDELVLINFTEDDARINALLSSQVDAIDQVPVALVDVLRSDERLRVLSAQTGTWLPFTMRVDRPPFDDVRVRQALRLIVDREQMINQVLSGQGRIGNDLYSPFDPAYASELPQRTQDIAEARRLLTEAGHPNLDIELVTAPIQAGAVEAAQVFQQQAKAAGVTIRLRRLDTTTFFGENYLSWDFAQSFWYTRNYLPQVASGALPEAPYNETHWNDPEFLDLVKRADRTVDQQERDELLKQAQRIEYERGGNIIWGFMNQVDAFQVYVAGLVPDRTGLPLSGYSFREVWLG

Crispr_ID: NZ_CP016353_7

• CRISPR_ID: NZ_CP016353_7
• CRISPR_location: 3008200-3008366
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP016353_7

Consensus_repeat	Method
TACCACGGCACCAGCACTGGCACCGG	CRISPRCasFinder

spacers of NZ_CP016353_7

>7.1|3008226|64|NZ_CP016353|CRISPRCasFinder
TACCACGCATGACTGCGGCGCCGGTACCACGCACGATCGCGGCATCCGCCGTGCCACCGACACC
>7.2|3008316|25|NZ_CP016353|CRISPRCasFinder
CTCCTATCGCTCCACCACCAGCGCG

CRISPR arrays and Neighbor proteins around NZ_CP016353_7

CRISPR arrays

The CRISPR arrays of NZ_CP016353_7

>merge|NZ_CP016353|7|3008200-3008366|CRISPRCasFinder
GGCGATGGCACCTGCCGTGGCGCCGGTACCACGCATGACTGCGGCGCCGGTACCACGCACGATCGCGGCATCCGCCGTGCCACCGACACCTACCACGGCACCAGCACTGGCACCGGCTCCTATCGCTCCACCACCAGCGCGTACCACGGCACCAGCACCGGCACCGG

>NZ_CP016353|7|6|3008200-3008366|CRISPRCasFinder
GGCGATGGCACCTGCCGTGGCGCCGG	TACCACGCATGACTGCGGCGCCGGTACCACGCACGATCGCGGCATCCGCCGTGCCACCGACACC
TACCACGGCACCAGCACTGGCACCGG	CTCCTATCGCTCCACCACCAGCGCG
TACCACGGCACCAGCACCGGCACCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091798031.1|3005908_3007648_+|pyruvate-dehydrogenase	unknown	unknown	gnl|CDD|180614
NZ_CP016353.1|WP_091798018.1|2992612_2993902_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|378963
NZ_CP016353.1|WP_091798027.1|3003408_3004296_+|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224651
NZ_CP016353.1|WP_091798065.1|3017999_3019274_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|224567
NZ_CP016353.1|WP_091798058.1|3014389_3015808_+|APC-family-permease	unknown	unknown	gnl|CDD|223605
NZ_CP016353.1|WP_091798937.1|3011463_3012006_+|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_CP016353.1|WP_091798029.1|3004300_3005227_-|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NZ_CP016353.1|WP_091798932.1|2996805_2997579_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP016353.1|WP_091798034.1|3007679_3007865_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091798037.1|3008749_3009508_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|367243
NZ_CP016353.1|WP_091798043.1|3010540_3011353_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|366444
NZ_CP016353.1|WP_091798024.1|2995643_2996723_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|223787
NZ_CP016353.1|WP_091798040.1|3009608_3010541_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|130256
NZ_CP016353.1|WP_091798934.1|2997878_3003401_+|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|227111
NZ_CP016353.1|WP_176879555.1|3013345_3014326_+|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274712
NZ_CP016353.1|WP_091798020.1|2993951_2994749_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
NZ_CP016353.1|WP_091798022.1|2994751_2995600_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213260
NZ_CP016353.1|WP_091798061.1|3015916_3017983_+|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl|CDD|369642
NZ_CP016353.1|WP_091798046.1|3012017_3012740_-|hypothetical-protein	unknown	unknown	gnl|CDD|237605
NZ_CP016353.1|WP_091798049.1|3012828_3013092_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091798031.1|3005908_3007648_+|pyruvate-dehydrogenase	gnl|CDD|180614	PRK06546, PRK06546, pyruvate dehydrogenase; Provisional.	0
NZ_CP016353.1|WP_091798018.1|2992612_2993902_-|FAD-dependent-oxidoreductase	gnl|CDD|378963	pfam12831, FAD_oxidored, FAD dependent oxidoreductase. This family of proteins contains FAD dependent oxidoreductases and related proteins.	5.15798e-67
NZ_CP016353.1|WP_091798027.1|3003408_3004296_+|MurR/RpiR-family-transcriptional-regulator	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.82291e-53
NZ_CP016353.1|WP_091798065.1|3017999_3019274_-|extracellular-solute-binding-protein	gnl|CDD|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	2.71229e-14
NZ_CP016353.1|WP_091798937.1|3011463_3012006_+|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	8.38457e-45
NZ_CP016353.1|WP_091798029.1|3004300_3005227_-|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	3.69561e-26
NZ_CP016353.1|WP_091798932.1|2996805_2997579_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	1.40069e-52
NZ_CP016353.1|WP_091798934.1|2997878_3003401_+|ATP-grasp-domain-containing-protein	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NZ_CP016353.1|WP_091798037.1|3008749_3009508_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	6.78382e-13
NZ_CP016353.1|WP_091798043.1|3010540_3011353_+|ABC-transporter-permease	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	3.12054e-17
NZ_CP016353.1|WP_091798024.1|2995643_2996723_-|ABC-transporter-substrate-binding-protein	gnl|CDD|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	3.48869e-18
NZ_CP016353.1|WP_091798040.1|3009608_3010541_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	2.16371e-101
NZ_CP016353.1|WP_176879555.1|3013345_3014326_+|PPOX-class-F420-dependent-oxidoreductase	gnl|CDD|274712	TIGR03666, Rv2061_F420, PPOX class probable F420-dependent enzyme, Rv2061 family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. A variant of the Partial Phylogenetic Profiling algorithm, SIMBAL, shows that this protein likely binds F420 in a cleft similar to that in which the homologous enzyme pyridoxamine phosphate oxidase (PPOX) binds FMN. [Unknown function, Enzymes of unknown specificity].	8.53519e-22
NZ_CP016353.1|WP_091798020.1|2993951_2994749_-|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.23222e-69
NZ_CP016353.1|WP_091798022.1|2994751_2995600_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.55576e-111
NZ_CP016353.1|WP_091798061.1|3015916_3017983_+|PQQ-dependent-sugar-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	1.1739e-19
NZ_CP016353.1|WP_091798046.1|3012017_3012740_-|hypothetical-protein	gnl|CDD|237605	PRK14086, dnaA, chromosomal replication initiator protein DnaA.	0.00287726
NZ_CP016353.1|WP_091798058.1|3014389_3015808_+|APC-family-permease	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	8.08587e-47

Protein sequences

>NZ_CP016353.1|WP_091798034.1|3007679_3007865_+|hypothetical-protein
MRESRARAGEIRARGAEIRIQDGEFRAQPGEFRARAGEIHGEAREIRVGGDESGDAAGWET
>NZ_CP016353.1|WP_091798031.1|3005908_3007648_+|pyruvate-dehydrogenase
MAKGSVADQFVEVLVQAGVSRIYGVVGDSLNPVVDAIRRTPGIDWVHVRNEEAGAFAAAAEAQLTGRLAVCAGSCGPGNTHLVQGLYDAHRTGAPVLALASHIPSNQIGTGFFQETHPERLFLDCSGYCEVISQPGQLPRIQRIAIQHALSRGEVSVLVLPGDVAQMDAEESTGTSLFVTESATLTPTAAQVDQLASMLDEAETVTLFCGAGVADAHAEVMELAGILKSPVGHSLRGKEWIQFDNPYDVGMSGLLGYGACYDAMRKADLLLLLGTDFPYDSFLPGARTVQVDHDATRLGRRTPLRLGVHGDVRETIRAVLPALREKTDRRFLDEMLRDHCRSLENVVDAYTRDVERHVPIHPEYVADVLDDLAADDAVFTVDTGMCNVWAARYVTPNGRRRVIGSFLHGSMANALPHAIGAQLAYPGRQVISMSGDGGLGMLLGELLTVKLHELPVKIVTFNNSSLGMVKLEMLVDGLPDYQTDHAGVDFAAIAAGAGIHSVRVTDPADVRDVLAEALAHPGPALVDVVTDPNALSMPPKITAAQVRGFALAASKVVLTGGVGKMVDLARSNLRNVPRP
>NZ_CP016353.1|WP_091798029.1|3004300_3005227_-|sulfite-exporter-TauE/SafE-family-protein
MQTLLLFGLAGFLAQLVDGSLGMAFGVTATTTLVTVGTAPAVASAAVHLAEVGTSLASGVSHWRFRNIDWRTVGILALPGAIGAVLGAYVLTSLSTESASVWITTILLVLGLYVLIRFAFLKLGKLITNKRPGAKFLGPLGLVAGFVDASGGGGWGPVATTTLLSSGRLEPRKVVGSVDTSEFIVALAASVGFFFSLSSEHDLNYTVVAGLMIGGVLAAPVAAWLVRRMPPRILGAAAGGLIVFTNARTLLTTSGAGTTLTISVLVAIVALWAAGLTAAVRSVRAEKRLNALVGEDGQTEEPAKLPTS
>NZ_CP016353.1|WP_091798027.1|3003408_3004296_+|MurR/RpiR-family-transcriptional-regulator
MTSTAPSTFDELAARLQDTLPELSRSHRLLAERVMADPEGVAFMTVYDLASAVGVNEATVVRFASAIGFKGFPELKKLCREKLREQAQLLRRFDLLEQRGAEEGGLPRRAAELDSANIARTFARIDTERWGQAVAALAEAPRVHVLGLRKCHAVAYLLGYLLRMVREDAETITAEAGTLTDSLRRIRKGDAFVAISIHRYSAETVRAAEWARARGARCVALTDNASSPLVPLADQVFFVDAAGPSVLRSVTAFTSLAQALVAEVAAALGKEVRDTLLHDEQLLEEFAVYTDPERR
>NZ_CP016353.1|WP_091798934.1|2997878_3003401_+|ATP-grasp-domain-containing-protein
MFTRVAIVNRGEAAMRLIHAVREVNAGGGHQLETIAFYTDADRTATFVREADHAYCLGAASARPYLDLAVLERALVDTRADAAWVGWGFVAEDPAFAELCARLGVTFIGPDAEAMRKLGDKIGAKLIAEEVGVPVAPWSRGAVADIDAALLAAKEIGYPLMLKATAGGGGRGIRVVTSDDELRDAYERTSAEAARAFGSGVVFLERLVTGARHVEVQVIADGQGTAWALGVRDCSVQRRNQKVIEESSSPLLDDAQTSELKASAERLAVAVGYRGAATVEFLYHPGEKLFAFLEVNTRLQVEHPITEATTGMDLVKAQLAVAAGEKLTGPVPAELGHAVEARLNAEDPDRDFAPAPGRIALLGLPAGPGIRVDTGVSEGDTIPADFDSMIAKIIAYGRDRDEALARLRRAVAETTVLIEGGSTNKSFLLDLLDAPEVIEASADTGWIDRVRAQGRLVSSKHSGIALATAAIEAYEDEERAERQRLLQTAFGGRPQVQHESGRPIDLKLRGVGYRVTVARTGPKRFRVGIADDAAVHHVDVEIDRFDERAGQLIANGQRFRFVTGTFGPVHLVEVDGASHRVSRDEGGVVRSPAPALVVATPVEVGDEVEAGAPVLVLESMKMETVLRAPFRATLRERPVAVGSQVETGAPLLRLEPLGDETDDTDGAAAPGVDLELPPEPGGVAASRRAAAGLADLRSRLLGFDIDPHDDSGALAGYLAARAELLALPDAGERPTRGEVELLRVFADLSELSRNRPAGEETKADTRVHSSREFFHTYLQSLDVERAGLSETFQQRLGRVLGHYGVTDLERGPELEEAVFRIFLAQQRAASDVTVITTLLQRWLTEPAPAADVRQTVGQTLEHLIVATQLRFPVVGDLARGVVFRWFAQPMLRRNRAEIYARVRKSLRYLDEFPEAADREDHIAEMVASPEPLVRVAGQRIGLRGADPGSLLEVLSRRYYRSSGLDNARLVRHGGTVCYVGDYEHGGRRRLVATAADFADVADALSAVASTAEAGSADSLVVDIYLTWARQPKEAEAMATVLGETLARVSLPETVRRVTATVAGNSGAAMHHHFTFRPSNEDGGRGGFAEDRLIRGLHPLIAQRFELRRWRDFDLTRLPSADEEVYLFRCVAPENRADERLVAMAQVRDLTPLRDDEGRILALPAVEGTLDACLDAIRKVQAKRPAKKRFDTNRVLLYVWPPSELTVDDLKAIAHRVLPTTAGAGLEEVLFLGRQRDADTGELTDIAVRISYTHDSGVRLSIVDPPTEPIEPLDDYGQKVLRARRRDTVYPYELTGMLAGEGGTFQEYDLDEARPASLVPVDRPKGRNTAGIVAGVVTSVTERYPEGMTRVVLLGDPTKALGALSEPECARVIAALDLAERLRVPVEWFALSAGARIAMDSGTENMDWVAAALKRIVRFTQDGGEINVVVAGINVGAQPYWNAEATMLMHTKGILVMTPDSAMVLTGKQSLDFSGGVSAEDNFGIGGYDRVMGPNGQAQYWAPDLAGARNVLMAHYDHAYVAPGESMPRRAETSDPAGRDISSFPHDVAGSDFTTVGEIFSREANPDRKKAFDIRTVMRAVADQDHAVLERWAGMADAETAVVQDVHLGGWPVCLLGIESRAVPRRGFPPTDGPDTYTGGTLFPRSSKKAARAINAASGNRPLVVLANLSGFDGSPESMRKLQLEYGAEIGRAIVNFVGPIVFCVISRYHGGAFVVFSKALNENMTVLAVDGSFASVLGGAPAAAVVFAGDVNARTAGDERVRELEARLAEAGGAERAALGTQLSEVRTAVRAEKLGEVAAEFDGVHSIRRAVEVGSVDAVIQAADLRPEIIAAIERGLTA
>NZ_CP016353.1|WP_091798932.1|2996805_2997579_-|IclR-family-transcriptional-regulator
MANERRSVLRRALRILDTFSDSANDLNLSEISRRSGVPLTTAHRIVGELHAWGALERNEAGEYRIGLRLWEVAALAPRSVGLQRIALPFMQDLYETTHRGVHLAVRTQDEVVFVERFVSPERASARPRVGGRYALHATAVGLVLLAHAPLELQEDVLGGPLESFTPQTYSSGRELRQVLADVRRSGYAVSDRQIDPDFVSVAAPIRGADDTVVAALSLIVPYTESHGPGLGHLVQATARGISRALGAHRPSNMRKGG
>NZ_CP016353.1|WP_091798024.1|2995643_2996723_-|ABC-transporter-substrate-binding-protein
MPAHSLTPPSPSAFSRRSFLRRSALATALAAAGPTVLSACGASPAAGGGGDGPTFLSYLPLETLSMAPELLAVAGGHFGKHGLDVTLQPVKGSPQAMQTLLAGVGPVTRIGQIDVMTAVAESDQPLVNIGTLTRGSSLRFVYSKENPLTKPEDFVGKTMGVPSEGGTSSKVVSLVLANAGLDPSKTPRQVVGLTPGTFNLVQQGRLAGYVVSIDTANIVLSQHEDAAAFDPGTTVRSDSQCYVADRNIVRDDPDTLKAFLAGIQDALAAFVADENFEETLGVLREKYSFATLDDDAIAVQSLTAMRELWTGGDPAAPLLVTDEAEWKAGYDELTAADEAAPGGDSSTWFDNSLLPAAAA
>NZ_CP016353.1|WP_091798022.1|2994751_2995600_-|ABC-transporter-ATP-binding-protein
MSAHHTDTLAPATKAGDDDRATEVPKLELIGVGKEFRTKRTTTQALSGITLSISDGEFVAVIGRSGCGKTTLLRTLAGLLSPSEGRILVEGRPLWSGSTVDSSVVSQLGVVFQEANLFPWYSVADNIALPLKLRGDDKRYRHQRAYELAELVGLQGFEKSYPRELSGGMRQRVAIARALSTHPKLLLMDEPFGALDALTRERMNLELQRIALAAHATVVFVTHDITEAVFLGDRVVQLSPRPGRISEIRPITFARPRDMDVQTEPRFGAIVRELRHALDGEG
>NZ_CP016353.1|WP_091798020.1|2993951_2994749_-|ABC-transporter-permease
MSKERLHKLLPWIGTPLILIVFFLLWDLFVRVNNMSELVLPRPGTVFTALGEVVSNPETWAHARVTAMETIGGFAIALVCGIAVGAVLGKVRWVERSLRPLIVASQVVPKVALIPLFVIWFGFGMTSKVIMSAMLAFFPIMLNVQLGVRSVESGQRDVMKALNASRWQTFKHLELKSTMPYVFAGMEVGIVFAIIGTIVGEYLGGSEGLGYLVVRTLNELDAPALFAVIILLSVLGLLLYFLVNGLKRFFIPWHESVYSQHDVNG
>NZ_CP016353.1|WP_091798018.1|2992612_2993902_-|FAD-dependent-oxidoreductase
MPHELTELKIKTVTRPSERPTERISAGICVVGAGIAGLSAAVEARKLGHSVVLVDALPVLGGQCVNSLIGLFCGVYGNGPEYRQLTHGIFDPMFADLGSTGDIHFNRSHTMTVNYDEVALSRWIENLVHSLDIQVVLGASVLDVDREGGKLGRVTFATRHGVVEVAADGFVDASGDAALTWEAGFPCRVPERTIWGSQQIRLENLREELRPEHAELSARVREKADEYGLLRKDGLAFFFPGRNTAVMNMTHVEAPLGAVRAAKAQLEGKAQADRVVEFLRKEFPGAFGEATVRIYGFPGRRQTRWIAASHQLSIDEVRHGTRFADAVARTAWPIELHDQPEGYVWETYDADHVHYVPLRSLLPEGAHNLVAAGRCVDGDAAALSSVRVMGPCAAMGHGAAHALDLAGGDSVHDIDHTELRKRLYDNVDR
>NZ_CP016353.1|WP_091798037.1|3008749_3009508_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MPEDNDARARLDLLWGGTQRSGRGPKPKLSLDHIIRTAIKIADTEGIEAVSMQRLASALGYTTMSLYRYVPSKDALIEVMIDTAAGQPAPYTGPPDDWRGELEAWTYSIWQTYMEHPWLTKANVTAPPTGPNNLAWFEAAIGPLSRAGVAGTDLISATLFLLGAVRGLAQIAVGVAGSRTSRGITAAEAAGSYEATLRELVDPQRFPHLSALIGEGTFTPDGEADENVDLDLQYGLQRMLDGIENFGGRDSR
>NZ_CP016353.1|WP_091798040.1|3009608_3010541_+|ATP-binding-cassette-domain-containing-protein
MRDGPAIEVRKLRKSYGGHHVLKGLDLEVRRGTMLALLGPNGAGKTTAVRILSTLLDFDSGVVKVAGYDVAGEGRAVRRAIGLTGQQTAVDGLLTGRENLVMMGKLQRLRGGASRRAADLLDQFDLRAAADRQVKTYSGGMRRRLDLAISLLTSPSVLFLDEPTTGLDPRSRTQVWATVRELLSGGVTVLLTTQYLEEADQLADRVAVVDGGRVVADGTPAELKHQVGAERLVLTFGSAEVVAVAADVLAEDNPNREDRMVSVPVAHAKDVRRILGRLADVGIEPDDLTVDKPTLDDVFLTLTGTHVGGQ
>NZ_CP016353.1|WP_091798043.1|3010540_3011353_+|ABC-transporter-permease
MSTIELSTRQDSSEWAGAAGNARVLIARSLRHILRSPEQLMLMLFLPIMMLLMFRYLFGGAINTGDVTYVNYVVAGIIAVSVTFNSTVASVAAATDMSEGIVERFRSMPMLSSTVLIGHVAASVVRNMVSIAVMIGVGFLVGFRPVAGFGAWLAAIGLLVLFAVAISWIAVLLGVLARSPEGASGMSMPLVFIPYVGSAFVPPSTMPDGLRQFAENQPVSLVVDSVRGLLMDLPVGNTAWLAVVWWVAILAIVIPVAGRIFRKRSTSPAA
>NZ_CP016353.1|WP_091798937.1|3011463_3012006_+|DinB-family-protein
MSTTTEAAQRTELTGEYADLHEQLAHLRHFLRFTTRDLTDEQVGLRTTASELCLGGLIKHVTAVERAWVAFARGDHGVMEWNPEDTAVMAERDAEFRMLPGETLAGVLGEYAVVAAGTDELLASRPDLDEVHPLPDAPWFEKGKSWSTRRVLLHIAAETAQHAGHADIIREAIDGAKSMG
>NZ_CP016353.1|WP_091798046.1|3012017_3012740_-|hypothetical-protein
MSAASSGPRDPGPHDPNPLDPRPGNTGPDGSPGPCAAQPQGDDRHPAAADQGRDPGDQARSRATDPDSRANPDPHPAWRPPRPWNQDPPEHQTATRHRDHTPGPTDHATADRYPGRPKAGLAVASLVTGAIGLVLAVSTWAAWLLVLPGFREAQPYSWIAVVFGLVLGALWFLVLPLGTVSIIVGLLATRRAPALAALARLGMVVALVALAAALGGAVVFVIDASTGAGPPVYPLVSSGG
>NZ_CP016353.1|WP_091798049.1|3012828_3013092_+|hypothetical-protein
MRESPAQDIEFRTRDVEFCVRDGELRVRDVELRIWRPQPARRGLFVIAVGILARCSVLGARCSVLGARCSVLGAGAARCLVLGRRAS
>NZ_CP016353.1|WP_176879555.1|3013345_3014326_+|PPOX-class-F420-dependent-oxidoreductase
MITPTPATPASTPSTPPAPSTPTTTPPTPNTLTPGTTTSSATTTTPPATTPGTTTPPTTAPHTTTTTGGVAPKVIAAVAGLVLLAGGFWALFAPASFADFAGFPAHTHFSHDLGAFQLGIGATLLLATIWGDALAVALAGFAVAGTVHAINHIVDLDEGGAVWQLVLLAVLSVAAGTGLALRLRSLGFVTGVVTTVTTPEFAHLVRQKTISLTTYRKDGRQGSSPVSIVVDGNKAFLRSFEKSLKTRRVARDSRVEVTRSNGSGRQLTGTPLPGNLRRLEGAENRNAARQMRRKYPILHGVIVPLVHRLGRSKTGRTVHFELTARP
>NZ_CP016353.1|WP_091798058.1|3014389_3015808_+|APC-family-permease
MSNPGAENGSLARVLGRMDVIAIAFGSMIGFGWIVLTGDFLDGAGAGGAALAFVIGGVVVGLVGLTYAELVSAMPAVGGEHNYALRALGSRPAFVTSWSLVLGYISVVAFEAVALPQTLLYLIPDLPAGLLWSVAGYDVYATWVGVGVLGAVALTVLNYVGVRPAAVFQNVAVLFLAAVGVLLTIGAVTGGSTANMEPLFTGGMSGVLVVLVATPFLFVGFDVIPQSAEEIDLPPRRIGRLLLWSVLLAVGWYVMIMLTVGSGLGAGERAGSEVPTADAMAWLWSSSAMGTVLVLGGIAGIITSWNGFLIGASRLLLAMAKSGMLPKWFGKVHPRFGTPSNAVLFIGVLSAIAPLFGRQMLVWLSDAGSLSIIVAYLMVALCFLVLRRREPAMPRPFRVPAGGVVGTTAIVLALGVGVLFLPGMPAELVWPYEWAIVGFWWLGGIVLVFRLPRVGPGVDADERLMATVRQRH
>NZ_CP016353.1|WP_091798061.1|3015916_3017983_+|PQQ-dependent-sugar-dehydrogenase
MSKPRWSLLATVTLVTTLLAGAPAAAQDEGPITDPIPEDPVTSELGLTVREFAQFPKSEPTPAPTDPRLMRHARINHLGELPDGSGRKYVPDLNGNLYFVPESGEPEVYLDVKAEFPDFFSGRGMGQGFGFVTFDPDFRRNGVFYTVHTEAGAALDKETTFPRQPRTQYHGIVTEWRADDPASDTFHGTSREILRLGFAQQIHGIQQIDFNPTAKRNSEDHGLLYIAVGDGGLGVSSTEPQDLSTPHGKILRIDPHGNDSVNGQYGVPASNPFVGQQDAVGEIFAYGMRDPHRFSWDPKRGPGGNRMFLGHIGQHAIESVYEVRKGDNLGWSEREGTFRYDRADDCYLYPLPDDDGNYDYVYPVAQYDHNPPPDWECGTDVGRAISGGFVYRGDDAPELRGKYLFADLVDGRVFYTESGEMRRGAEPATIHTMRLYDENGNWVTTPELAGDTRVDLRFGRDADGELYLLSKANGKIWKITGTKRFADCPTGSTVVKNAMGEKNWAPVTPEKWEFPRREVVLAEEGSERPGPRRPYEYAVLTKGPEFGSVRLDAQVRLDTPVEVTNRDVVLVFGYQSDTRFYYAHLSTDNTIYPHNGIFVVDDADRERIDHQWDPVRSQGAAPAITDAEWHEVSLTHCAETGEIAVYVDGQRDPLMTAVDPTFTSGRVGFGSFDNVGRLRDLSVMGRKS
>NZ_CP016353.1|WP_091798065.1|3017999_3019274_-|extracellular-solute-binding-protein
MKTARTAVLLVLLALLTQVSACTTAERVTIIGPWTGTEEAAFRAVLDEFERETGIGYDYLGTRSLSPVLAADVQQGTPPDIAILSSPNELVNYQRQGALRQLPELEDELRSAYSPQWLQLAQAGTERPYAVVVKAALKGLVWFNPNVLTGPVPRTWNQLVSLTDAAAAEGRTPWCMGMGAMSATGFPGSDWIEDILLRRYGPETYQRWVTGDLPWTAPEVRESWIAWGELILGDGAVHGGRGGSLLTNYTTANDTMFAADPGCFLEHQGSYVVNDYRSKGARFDFFPTPGPSGPGDAWLVSADLATMFRDTPAARELMRFLASAEGQRIWPEADRGAVFTVRQDVAATTGSDAVTRNVARIISTAKVLCYDASDLMPTAVTNAFHRAALGYLADPGRLDQLLAELERIRTGVSAQDWANVVCGR

Crispr_ID: NZ_CP016353_8

• CRISPR_ID: NZ_CP016353_8
• CRISPR_location: 3610822-3610929
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP016353_8

Consensus_repeat	Method
TTGCTGGCCCTGCTGGCCATAGCC	CRISPRCasFinder

spacers of NZ_CP016353_8

>8.1|3610846|60|NZ_CP016353|CRISPRCasFinder
GGGCTGCTGGCCGTAACCCGGTTGCTGCCCGTAGGTGTTCGGGTCGTAGCCCTGCTGACC

CRISPR arrays and Neighbor proteins around NZ_CP016353_8

CRISPR arrays

The CRISPR arrays of NZ_CP016353_8

>merge|NZ_CP016353|8|3610822-3610929|CRISPRCasFinder
TTGCTGGCCCTGCTGGCCATAGCCGGGCTGCTGGCCGTAACCCGGTTGCTGCCCGTAGGTGTTCGGGTCGTAGCCCTGCTGACCTTGCTGGCCTTGCTGGCCATAGCC

>NZ_CP016353|8|7|3610822-3610929|CRISPRCasFinder
TTGCTGGCCCTGCTGGCCATAGCC	GGGCTGCTGGCCGTAACCCGGTTGCTGCCCGTAGGTGTTCGGGTCGTAGCCCTGCTGACC
TTGCTGGCCTTGCTGGCCATAGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091805016.1|3615220_3616117_-|YegS/Rv2252/BmrU-family-lipid-kinase	unknown	unknown	gnl|CDD|237021
NZ_CP016353.1|WP_091805012.1|3609026_3610220_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|234945
NZ_CP016353.1|WP_091805333.1|3621310_3622738_+|bifunctional-phosphatase-PAP2/diacylglycerol-kinase-family-protein	unknown	unknown	gnl|CDD|224513
NZ_CP016353.1|WP_091805322.1|3602913_3603615_-|HAD-family-hydrolase	unknown	unknown	gnl|CDD|319817
NZ_CP016353.1|WP_091804999.1|3603695_3604775_+|hypothetical-protein	unknown	unknown	gnl|CDD|238861
NZ_CP016353.1|WP_091805002.1|3605073_3605307_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091805022.1|3617534_3617753_-|bacteriophage-holin	unknown	unknown	unknown
NZ_CP016353.1|WP_091805328.1|3611167_3613954_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|226947
NZ_CP016353.1|WP_091805006.1|3606932_3607598_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP016353.1|WP_091805001.1|3604787_3605087_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091805018.1|3616136_3617096_-|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl|CDD|376413
NZ_CP016353.1|WP_091805004.1|3605324_3605780_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|214628
NZ_CP016353.1|WP_091805020.1|3617147_3617492_-|Sec-independent-protein-translocase-subunit-TatA	unknown	unknown	gnl|CDD|234797
NZ_CP016353.1|WP_091805026.1|3618739_3619741_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP016353.1|WP_091805024.1|3617762_3618743_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
NZ_CP016353.1|WP_091805008.1|3607623_3608571_+|5'-3'-exonuclease	unknown	unknown	gnl|CDD|214682
NZ_CP016353.1|WP_091805325.1|3605776_3606922_-|aminopeptidase-P-family-protein	unknown	unknown	gnl|CDD|223085
NZ_CP016353.1|WP_091805028.1|3619802_3621161_-|Pup--protein-ligase	unknown	unknown	gnl|CDD|274725
NZ_CP016353.1|WP_143021378.1|3608551_3608977_-|DUF4333-domain-containing-protein	unknown	unknown	gnl|CDD|379513
NZ_CP016353.1|WP_091805331.1|3614843_3615236_+|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl|CDD|225197

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP016353.1|WP_091805024.1|3617762_3618743_-|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	3.4e-60	198.8	0.1
NZ_CP016353.1|WP_091805026.1|3618739_3619741_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	9.6e-47	154.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091805016.1|3615220_3616117_-|YegS/Rv2252/BmrU-family-lipid-kinase	gnl|CDD|237021	PRK11914, PRK11914, diacylglycerol kinase; Reviewed.	1.7565e-77
NZ_CP016353.1|WP_091805012.1|3609026_3610220_-|GNAT-family-N-acetyltransferase	gnl|CDD|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	6.46673e-110
NZ_CP016353.1|WP_091805333.1|3621310_3622738_+|bifunctional-phosphatase-PAP2/diacylglycerol-kinase-family-protein	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	6.947e-23
NZ_CP016353.1|WP_091805322.1|3602913_3603615_-|HAD-family-hydrolase	gnl|CDD|319817	cd07515, HAD-like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily. The haloacid dehalogenase-like (HAD) hydrolases are a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members include 2-L-haloalkanoic acid dehalogenase (C-Cl bond hydrolysis), azetidine hydrolase (C-N bond hydrolysis); phosphonoacetaldehyde hydrolase (C-P bond hydrolysis), phosphoserine phosphatase and phosphomannomutase (CO-P bond hydrolysis), P-type ATPases (PO-P bond hydrolysis) and many others. Members are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.86592e-29
NZ_CP016353.1|WP_091805008.1|3607623_3608571_+|5'-3'-exonuclease	gnl|CDD|214682	smart00475, 53EXOc, 5'-3' exonuclease.	4.27326e-79
NZ_CP016353.1|WP_091805328.1|3611167_3613954_-|DEAD/DEAH-box-helicase	gnl|CDD|226947	COG4581, COG4581, Superfamily II RNA helicase [DNA replication, recombination, and repair].	0
NZ_CP016353.1|WP_091805006.1|3606932_3607598_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.33101e-18
NZ_CP016353.1|WP_091804999.1|3603695_3604775_+|hypothetical-protein	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	3.84555e-20
NZ_CP016353.1|WP_091805018.1|3616136_3617096_-|twin-arginine-translocase-subunit-TatC	gnl|CDD|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	2.59213e-76
NZ_CP016353.1|WP_091805004.1|3605324_3605780_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	1.1208e-37
NZ_CP016353.1|WP_091805020.1|3617147_3617492_-|Sec-independent-protein-translocase-subunit-TatA	gnl|CDD|234797	PRK00575, tatA, Sec-independent protein translocase subunit TatA.	9.97886e-25
NZ_CP016353.1|WP_091805026.1|3618739_3619741_-|WYL-domain-containing-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.30863e-37
NZ_CP016353.1|WP_091805024.1|3617762_3618743_-|YafY-family-transcriptional-regulator	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	7.81165e-47
NZ_CP016353.1|WP_091805325.1|3605776_3606922_-|aminopeptidase-P-family-protein	gnl|CDD|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	2.48095e-100
NZ_CP016353.1|WP_091805028.1|3619802_3621161_-|Pup--protein-ligase	gnl|CDD|274725	TIGR03686, pupylate_PafA, Pup--protein ligase. Members of this family are the Pup--protein ligase PafA (proteasome accessory factor A), a protein shown to regulate steady-state levels of certain proteasome targets in Mycobacterium tuberculosis. Iyer, et al (2008) first suggested that PafA is the ligase for Pup, a ubiquitin analog attached to an epsilon-amino group of a Lys side-chain to direct the target to the proteasome. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP016353.1|WP_143021378.1|3608551_3608977_-|DUF4333-domain-containing-protein	gnl|CDD|379513	pfam14230, DUF4333, Domain of unknown function (DUF4333). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 140 and 255 amino acids in length. There are two completely conserved C residues that may be functionally important.	2.71778e-14
NZ_CP016353.1|WP_091805331.1|3614843_3615236_+|MmcQ/YjbR-family-DNA-binding-protein	gnl|CDD|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	4.8321e-46

Protein sequences

>NZ_CP016353.1|WP_091805012.1|3609026_3610220_-|GNAT-family-N-acetyltransferase
MSDLVTRVLRDDELRAANTLFRASLHVPPVKDEEWVTTHRGYQPERTLGVFDEALIGTAKSTDALLRVPGGADVPLAAVTGVGVRADRTRRGVLTSLMRAQFADFAERGIVAAALHASEGVIYGRFGYGVGTLMRSYKVRRLAARLRSDLPTSGEIELLDIDAALNRLPGSYAGLPLRPGMMSRPQHWWYAVERGLRASEEPVVTAVHHGPDGIDGFVVYRVVRTPGSDGTLKVDDLHYGTPEAFAGLWRFLLGVDLVDEIQVGYGPVTEPVELLFTDPRMCTVTEVEDDTWVRLVDVEAALLARERAAGPLVIEVDDPFLPHNAGRYLITPDEVSRTERDAQLRMGADTLAMAYLGAWLPSSLAATGRIRVSDPGAVAVADDLFGARSTPWCGTFF
>NZ_CP016353.1|WP_143021378.1|3608551_3608977_-|DUF4333-domain-containing-protein
MLVAAVSCGFLLLGACDNGGGDSGGSGEDAGTGARESTGSRPSGTSAPAVTSGTETGVAPVTRVFDPETMRTSVLQVLEDGYRVADIEDVTCPADQPVEVGTTFDCTARIAGQDVPVPIAVNTEEGQYEVGQPAEVSGPTP
>NZ_CP016353.1|WP_091805008.1|3607623_3608571_+|5'-3'-exonuclease
MTTAPLALLDAASLYFRSYFALPDSLTAPDGTPVNAVRGFTDTIARIITDRGPGRLVACLDADWRPQFRVDALPSYKAHRVVETAPSDGVDVEEVPDTLTPQIPIILEVLEAAGLATALARGFEADDVIGTLTIREKTDPVEIITGDRDLFQLVRTEPTPASVIYVGKGWAKAEVLGPAEVAAKYGIPVTAAGPGYADMSMLRGDPSDGLPGVAGIGEKTAAKLITQFGSLETLVAAAEAESTELPLKTRTRLNEAADYLAVAPTVVRVAPDAPVEFSGDDRLSPSAADPDRLTELARRWNLGGSVPRLLTALGH
>NZ_CP016353.1|WP_091805006.1|3606932_3607598_-|class-I-SAM-dependent-methyltransferase
MAPFQNPFFARLFQRIGDRNEARGQAELRRELLAGLTGSVVEVGAGTGLNFAYYPDEVTGVAAVEPEPSLRSEARRVVASAPVPVPVSVVAATADRLPFEDGSADAVVVSGVLCSVADPVAALAEFARILAPGGELRFYEHVRSPQRVRALIQDAADLVWPRLMGGCHPNRDPLATMRAAGWLPVRWRELIFPYGAKISVVAPRVLGVARPASAREGGAPG
>NZ_CP016353.1|WP_091805325.1|3605776_3606922_-|aminopeptidase-P-family-protein
MSRRSLHTPAPDAAALRARLDRARDAASDAGTDALLIAPGSDLRYLIGQAVGSFERLTALVVPASGAAPALVLPKLEAPGYTDVPTDDLGVDVLTWVDGDDPYALVAGRLGKPGRVAVSDTMAALHVLGLRDAIGSAEQTLAGPVIRELRMRKDAAEIAALRTAGAAIDRVHARMGEWLRPGRTEAEVGADIAAAIVAEGHTEAEFVIVGSGPNGASPHHDVSGRVIENGDVVVIDIGGPIAEGYNSDSTRTYAVGQPRDADVAGTYEVLRRAQRAAVEAVRPGATAQDIDAAARTIIAEAGFGEYFIHRTGHGIGLDVHEEPYIVGGNDLVLEPGMAFSVEPGIYQPGRWGARIEDIVVVTSDGMEPLNNRPHELVVLGS
>NZ_CP016353.1|WP_091805004.1|3605324_3605780_-|Lrp/AsnC-family-transcriptional-regulator
MTNPGLEPLDQAIVRELAADGRRSFTDLAERVGLSVSAVHQRVRRLEQRGVIRGYTAKLDGEQIGLPLTALISLTPNDPAAPDDYPQRLEHITEIESCYSVAGDESYILLVRVASPLGLEDLLRRIRESAKVSTRTTVVLSTPFEGRSPTL
>NZ_CP016353.1|WP_091805002.1|3605073_3605307_-|hypothetical-protein
MATRKVTLSLDEGALEFAERAAKAHGVSVSSWLSKAARREAVRTGYHKPARPQTAETAAAADESEIAAALEDLRAQG
>NZ_CP016353.1|WP_091805001.1|3604787_3605087_-|hypothetical-protein
MRRGEVWTYHPPTEQARSRAVLLLSSDGVNESERPWLLGTELLEKDPQDILGVAVDARFWISTLNLTRVYRPWLDQRIAEIGDDVQEQIDSALRAALDL
>NZ_CP016353.1|WP_091804999.1|3603695_3604775_+|hypothetical-protein
MARSRWWLGAFALVGVALLVGVFVLIGQDRTPPDRPGPPGRGPLTVVTIGDSTLSGEGAGDYTADTNGKDGNWCHRSPNAAVNKIELPGVTKAVNLACSGAPAGQIGLGTVKQWTEPSQAQQLATLVKDHRVTAIVVAVGANDDPHFSRLISECFTSWFMDDGNPCSEKIKDDWQSRIDAMVPKVVSALRDIKKVLRTAGYSAEDYQLVLQSYAAPISPDIPEDLRNLNGCPFRTDDLRWVKETGAADLTEGLRSAAEQADVRFLDLSRSGEGHEACSGGADPSTEWFTRFTVEWNDLTDADRFSHAIQESFHPNAEGHAQLARCLSEFLGTSERSAACLKGEDGNLHAAPSVLAQNDR
>NZ_CP016353.1|WP_091805322.1|3602913_3603615_-|HAD-family-hydrolase
MRRVRHDRQVLIFDADDTLWENNILFERAIDGFLDWVAHPTLDRTAIRGVLDDIERANSAAHGYGSTVFLRSLGDCFATLHSRPASAAELRHLEELASALVEGKVEPMPGVARTLEALGQRHELLLLTKGDTGEQERKIAASRLARHFREVHIVAEKTVDTYWRLAERNSLVPETTWMIGNSPKSDILPARQAGMNAVFIPNEHTWVLEHGELDPADDGVLTLTTFPELLRHF
>NZ_CP016353.1|WP_091805328.1|3611167_3613954_-|DEAD/DEAH-box-helicase
MWNPDAVDQASSPTPAEAYQAARRRGRYPQLTRFSGEVSFEFDDFQTRGCQALEDGHGVLVCAPTGAGKTVVGEFAVHLALAEGRKCFYTTPIKALSNQKYADLTSRYGPDQVGLLTGDTAINGNAQIVVMTTEVLRNMLYAGSSALHDLGYVVMDEIHYLADRFRGAVWEEVILHLPEYVRVVGLSATVSNAEEFGEWLVEVRGDTTVVVDEHRPVPLWQHMLVGNRMFDLFAGERDDGPGEKNGEATINPMLLRRAEDMGRMHAPAGLRGRGRGRGQGARVPRFRPPSRVDMIDRLDNAALLPAIVFIFSRAGCDAAVTQCVRSGLRLNTPEEIAEVRRVVDERTAELPESDLGVLGYWEWREALEQGIAAHHAGLLPAFKETVEELFVRGLVKVVFATETLALGINMPARTVVLERLVKYNGEAHVDLTPGEYTQLTGRAGRRGIDIEGHAVVVWQPGVDPRQVAGLASTRTYPLRSSFRPGYNMAINLVGQFGTEQARDLLEQSFAQFQADRSVVGTARRIERNKEALTGYADAVSGDFDDLLSYVELRKRVSEREKLLARQNSATRRAQTAESLGKLRKGDVISVPQGRRAGLAVVVDPGLDPIHEPRPVVVTEDRWSGPLSVSDFPAPVESLGTVRLPKHVELRSPKTRRDIASSLRNTGITRPPRERRRSGANEDAELATLRAELREHPAHGLADREASLRWVERYQRLAGETAHLERKVAATTHSLARAFDRIRALLAERGYFTAEDVVTEHGRMLSRLYSESDLLAAECIRHGIWNGLTPPELSAVVSVLVYEARRDAAAEPRLPSGGVPKAWQETARLWTELVEDERRHRLTRTREPDAGFAWPVYRWSRGESLEKVLTAAEANGQELSAGDFVRWSRQVIDLLDQIKDVLGRDHPVGAVAAKAVKTLRRGVVAAGDV
>NZ_CP016353.1|WP_091805331.1|3614843_3615236_+|MmcQ/YjbR-family-DNA-binding-protein
MKPRELRAACLALAGSTEEFPFGEDNSVFKVGGKIFALSRLPGHPLRVSLKCDPEIALQLRATHPAITGGYHLNKRHWNTVLLDGSVPDTLVRELIEDSYDLVVAGLPKAKRERLRWAALGDEERGQPLA
>NZ_CP016353.1|WP_091805016.1|3615220_3616117_-|YegS/Rv2252/BmrU-family-lipid-kinase
MGIRAALAVHPDSGRGAAARIADAVAARLRTEVDRLDLLAANTVEQSRALMTDSRAAGLDVLIVLGGDGAVHQAVQFCAGTDVALGIVPSGTGNDLARALGVPASPDAAADAVAGALRSGSRRRIDLGRTGDGTWFGTVLCSGFDAAVNARANRMRWPEGPRRYDLAVVAELAALRPGRLTLDTGSERWHGEAILAAVGNTGWYGGGIPICPSASPDDGVFDVTVVGKVPRRTLARLLPSLRSGKHVHHPAVRTLRARSVELSCDGWPAYADGESLGTLPKRVTCVPGALTVLGQASG
>NZ_CP016353.1|WP_091805018.1|3616136_3617096_-|twin-arginine-translocase-subunit-TatC
MAESSGTRARRGGKRRHRSRRHNPDGTMTLVEHIYEFRRRLGYALLALVAGGIIGFIWFQNRVGPIPSLGDIVTGPYCAIPQGQRYPPEGPCRLLQTVPFEAFMIQLKVGLTAGAVLFAPLWLYQLWAFIAPGLYSKERKYALTFVGFASVLFALGACLAYFMTPHALELLTNFGGGSFTTWFTGDKYISFVLSLLLIFGVSFELPLLIIMLNRVGVVRYDQMKKWRRGIIFALFVFAAFVTPADPFSMLALAFALTLLFEFALQITRLHDRKRDRLRADEGWDKLDDDEAAPFNYTPSSVGDDSAQGKQRPASTDDIT
>NZ_CP016353.1|WP_091805020.1|3617147_3617492_-|Sec-independent-protein-translocase-subunit-TatA
MGALQPWHLIILVLLVVVLFGAKRLPDAARSIGKSMKIFKAETKDMRGSGESEQEATDAEPKQLATPQVTTNAAAPATPGAEKDQQLADLQRQLDELKKQQPGSAADQTQRNPS
>NZ_CP016353.1|WP_091805022.1|3617534_3617753_-|bacteriophage-holin
MFYVLSACLVALGILVLVVITIRSARLLRRYGRTASMVSASTHDQLGLLRARVAAVKVAIGQRRGRSRTHNG
>NZ_CP016353.1|WP_091805024.1|3617762_3618743_-|YafY-family-transcriptional-regulator
MSGSTERLPRLLALVPYLLARPGIKIEQAAQDFDVSAKQLRKDLELLWMCGLPGYGPGDLIDLFFDGDTVSVTFDAGMNRPLRLTGAEASALVIALRALAETPGVVDTAAVHRAIAKIEAAAGNAQPSGVVVGRGTREREATAKTRETLRGALQAGRALRIRYYTASSDRMSVRTVDPMRLLIVQGTSYLEAWCRKAGDVRLFRLDRIDELTVLDERADPPKGARPTDLSSGVFSPRPEHGEAQLVLSRDARWVAEYYPCEEVAELDGGELRVRMRYGDQSWMLRLVLGLGGDVRVEHPPELATAVRQRAVDALARARHLPVTFAQ
>NZ_CP016353.1|WP_091805026.1|3618739_3619741_-|WYL-domain-containing-protein
MSTARAERLVNLVLALLSTRQYLTAERIRGIVPGYADAATDDAFSRMFERDKTELRELGIPLETGRNSTFDPVEGYRIARRDYELGEIDLAPDEATAVALAVRLWDSPELTGQAHGALVKLRAAGVEVDENASPVVEPRVHTEPAFAPLLAAVQSGQVVRFDYRRSDSPERRTRTLEPWGVVSWKARWYVVGHDRDRKAPRCFRLSRITGEVSTAGKKGEVRRPPGVNLLELVATGSNAETSPIAKAKLWVAEGRAAGVRRHATVVGGMTLGGAGDVADAGEYGDIVEIDLYYPESAADWIAGHGPDVLVLEPDVLAKAVRDRLERVAQGERA
>NZ_CP016353.1|WP_091805028.1|3619802_3621161_-|Pup--protein-ligase
MQRRIFGIETEFGVTCTFHGQRRLSPDEVARYLFRRVVSWGRSSNVFLSNGSRLYLDVGSHPEYATAECDDLTQLVTHDKAGERILEDLLVDAERRLADEGIGGDIFLFKNNTDSAGNSYGCHENYLVTRAGEFSRIADVLLPFLVTRQLICGAGKVLQTPRGAVYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERYRRLHVIVGDSNMAEPTTLLKVGAAHLVLEMIEQGVQFRDFTLDNPIRAIREISHDLTGRRQVRLAGGREASALEIQREYHARAVQHVEAGGPNPTAERVTELWGRALDAVEQQDFSKIDTEVDWAIKHRLVERYRAKHDLDLSDPRVAQLDLAYHDIRRGRGVFDLLQRKGLVRRVTDDGEIELAKDTPPQTTRAKLRGDFIAAAQQAGRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVERLINSL
>NZ_CP016353.1|WP_091805333.1|3621310_3622738_+|bifunctional-phosphatase-PAP2/diacylglycerol-kinase-family-protein
MTRSAALPASRADTVLAAVSRSANKGSLWWVVASLLALRKGPSRRGALRGAVAIGGASAAANLIGKPLFPRRRPAAEIVPEARRLVKRPTSSSFPSGHAASAAAFVTAVTMESPAAGAAVLPLAAAVAYSRVHTGVHWPSDVGAGALIGVAAGLATRHWWPLHADGHGLTAHRADAPLMKDGEDMLAVVNPGSGNADIDPTEEVRFAWPKATLLYPDNGVDIRGQLNAEITRRKGKVRALAVAGGDGTVAAVASVAADHALPLALIPTGTFNHFARDVGVRSMPDADAATEAGKAVGIDLGEVEVGGGDGTGRRWFVNTASLGGYPEMVRLREKIEQRHPKWPSAVLAMVRTLRYARPLRVTINGKPALVWMIFVGNGTYSPKGFWPTHRPALDTGLLDVRYLRADLPYSRARFVAAVLTNTLSASHVYRQYDLASVDVRLLDGNRRVATDGEVGALGSAFRFRSRPSALTIYRL

Crispr_ID: NZ_CP016353_9

• CRISPR_ID: NZ_CP016353_9
• CRISPR_location: 4403442-4403774
• CRISPR_type: Orphan
• Repeat_type: I-C,I-E,II-B
• Spacer_info: 5 spacers

Consensus repeat of NZ_CP016353_9

Consensus_repeat	Method
GGACCACCCCCGCGCGTGCGGGGAAGAC	PILER-CR
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CRISPRCasFinder
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CRT

spacers of NZ_CP016353_9

>9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT
CTGGTCCTGAAGCTGGTCCCCGAGCTGGCCCCG
>9.2|4403531|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT
CGCCCGACCCAACGCAGACGGTCGGACGGAACC
>9.3|4403592|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT
GTCGTGGCGCGAGTGTCGGACCTGGAGGCCCTG
>9.4|4403653|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT
CTTCATCCGGAGGGGGAAGTCATGAGCAGGCAC
>9.5|4403714|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT
TTACTGAGCGCACCAGCCTGGTCAACCGTGCCT

CRISPR arrays and Neighbor proteins around NZ_CP016353_9

CRISPR arrays

The CRISPR arrays of NZ_CP016353_9

>merge|NZ_CP016353|9|4403442-4403774|PILER-CR,CRISPRCasFinder,CRT
GTCTTCCCCGCACGCGCGGGGGTGGTCCCTGGTCCTGAAGCTGGTCCCCGAGCTGGCCCCGGTCTTCCCCGCACGCGCGGGGGTGGTCCCGCCCGACCCAACGCAGACGGTCGGACGGAACCGTCTTCCCCGCACGCGCGGGGGTGGTCCGTCGTGGCGCGAGTGTCGGACCTGGAGGCCCTGGTCTTCCCCGCACGCGCGGGGGTGGTCCCTTCATCCGGAGGGGGAAGTCATGAGCAGGCACGTCTTCCCCGCACGCGCGGGGGTGGTCCTTACTGAGCGCACCAGCCTGGTCAACCGTGCCTGTCTTCCCCGCACGCGCGGGGGTGGTTT

>NZ_CP016353|9|5|4403442-4403774|PILER-CR
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CTGGTCCTGAAGCTGGTCCCCGAGCTGGCCCCG
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CGCCCGACCCAACGCAGACGGTCGGACGGAACC
GTCTTCCCCGCACGCGCGGGGGTGGTCC	GTCGTGGCGCGAGTGTCGGACCTGGAGGCCCTG
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CTTCATCCGGAGGGGGAAGTCATGAGCAGGCAC
GTCTTCCCCGCACGCGCGGGGGTGGTCC	TTACTGAGCGCACCAGCCTGGTCAACCGTGCCT
GTCTTCCCCGCACGCGCGGGGGTGGTTT

>NZ_CP016353|9|8|4403442-4403774|CRISPRCasFinder
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CTGGTCCTGAAGCTGGTCCCCGAGCTGGCCCCG
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CGCCCGACCCAACGCAGACGGTCGGACGGAACC
GTCTTCCCCGCACGCGCGGGGGTGGTCC	GTCGTGGCGCGAGTGTCGGACCTGGAGGCCCTG
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CTTCATCCGGAGGGGGAAGTCATGAGCAGGCAC
GTCTTCCCCGCACGCGCGGGGGTGGTCC	TTACTGAGCGCACCAGCCTGGTCAACCGTGCCT
GTCTTCCCCGCACGCGCGGGGGTGGTTT

>NZ_CP016353|9|4|4403442-4403774|CRT
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CTGGTCCTGAAGCTGGTCCCCGAGCTGGCCCCG
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CGCCCGACCCAACGCAGACGGTCGGACGGAACC
GTCTTCCCCGCACGCGCGGGGGTGGTCC	GTCGTGGCGCGAGTGTCGGACCTGGAGGCCCTG
GTCTTCCCCGCACGCGCGGGGGTGGTCC	CTTCATCCGGAGGGGGAAGTCATGAGCAGGCAC
GTCTTCCCCGCACGCGCGGGGGTGGTCC	TTACTGAGCGCACCAGCCTGGTCAACCGTGCCT
GTCTTCCCCGCACGCGCGGGGGTGGTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_170140147.1|4395361_4395499_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091810256.1|4401099_4402014_+|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224662
NZ_CP016353.1|WP_091810031.1|4409166_4409967_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224045
NZ_CP016353.1|WP_091810029.1|4408087_4409170_+|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|376439
NZ_CP016353.1|WP_091810012.1|4395871_4396603_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|223979
NZ_CP016353.1|WP_091810015.1|4397831_4399730_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091810010.1|4394063_4395305_-|hypothetical-protein	unknown	unknown	gnl|CDD|226089
NZ_CP016353.1|WP_091810026.1|4405897_4406914_-|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238566
NZ_CP016353.1|WP_091810018.1|4400272_4400899_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP016353.1|WP_110057688.1|4410128_4411352_+|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340817
NZ_CP016353.1|WP_091810020.1|4402269_4403031_-|PIG-L-family-deacetylase	unknown	unknown	gnl|CDD|225031
NZ_CP016353.1|WP_091810017.1|4399849_4400239_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091810028.1|4407035_4408091_+|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|376439
NZ_CP016353.1|WP_091810025.1|4404838_4405795_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091810032.1|4411592_4412936_+|MHS-family-MFS-transporter	unknown	unknown	gnl|CDD|340927
NZ_CP016353.1|WP_091810022.1|4403835_4404192_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091810034.1|4413000_4414218_-|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|366675
NZ_CP016353.1|WP_091810023.1|4404188_4404662_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091810008.1|4392490_4393885_-|DUF4389-domain-containing-protein	unknown	unknown	gnl|CDD|379561
NZ_CP016353.1|WP_091810014.1|4396599_4397751_+|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	unknown	unknown	gnl|CDD|350159

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091810256.1|4401099_4402014_+|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein	gnl|CDD|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	2.61617e-18
NZ_CP016353.1|WP_091810031.1|4409166_4409967_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	4.32181e-121
NZ_CP016353.1|WP_091810018.1|4400272_4400899_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	4.77214e-12
NZ_CP016353.1|WP_091810028.1|4407035_4408091_+|iron-ABC-transporter-permease	gnl|CDD|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.2416e-75
NZ_CP016353.1|WP_091810026.1|4405897_4406914_-|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	3.53562e-60
NZ_CP016353.1|WP_091810029.1|4408087_4409170_+|iron-ABC-transporter-permease	gnl|CDD|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.4358e-61
NZ_CP016353.1|WP_091810010.1|4394063_4395305_-|hypothetical-protein	gnl|CDD|226089	COG3559, TnrB3, Putative exporter of polyketide antibiotics [Cell envelope biogenesis, outer membrane].	2.97118e-29
NZ_CP016353.1|WP_091810020.1|4402269_4403031_-|PIG-L-family-deacetylase	gnl|CDD|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	3.08846e-32
NZ_CP016353.1|WP_110057688.1|4410128_4411352_+|glycosyltransferase-family-1-protein	gnl|CDD|340817	cd03784, GT1_Gtf-like, UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.	4.70987e-61
NZ_CP016353.1|WP_091810032.1|4411592_4412936_+|MHS-family-MFS-transporter	gnl|CDD|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.17733e-150
NZ_CP016353.1|WP_091810012.1|4395871_4396603_+|NUDIX-hydrolase	gnl|CDD|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	2.36827e-24
NZ_CP016353.1|WP_091810034.1|4413000_4414218_-|FAD-dependent-monooxygenase	gnl|CDD|366675	pfam01494, FAD_binding_3, FAD binding domain. This domain is involved in FAD binding in a number of enzymes.	3.08594e-56
NZ_CP016353.1|WP_091810008.1|4392490_4393885_-|DUF4389-domain-containing-protein	gnl|CDD|379561	pfam14333, DUF4389, Domain of unknown function (DUF4389). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 104 and 223 amino acids in length. There is a single completely conserved residue R that may be functionally important.	3.45538e-08
NZ_CP016353.1|WP_091810014.1|4396599_4397751_+|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	gnl|CDD|350159	cd09008, MTAN, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs): bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	2.03333e-51

Protein sequences

>NZ_CP016353.1|WP_091810020.1|4402269_4403031_-|PIG-L-family-deacetylase
MPLSALPEESFQRVLCVVAHPDDMEYGTSAAVARWTARGIRVGYLLLTRGEAGMPNPPEETARLRVAEQRAACAAVGVEDLTVLEHPDGVLVYSLDLRRDICREIRRFKPDVVLGGGTDIDTPHGFEQADHRAAGLATLDALRDADNRWVFPEQVDDEGLEPHSVRWFLVPGLAGSGATHGVDVTGEPLRRGVASLEAHAAYLAALPEHPAPADFIPMFTAMSGKAMGVEHAVLFRARDLQAPPEFNSETTQD
>NZ_CP016353.1|WP_091810256.1|4401099_4402014_+|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein
MRRVVILGGYGAVGREVVAGLLGHVPDVVVAGRDLAKAGTVAGATPLRLDLRDDDLSLLDADAVVMCADQENVRGARACLARGVHYVDVSADHKVLTGIGELHNLAVEHEATAVLSVGLVPGVTNLLARSLNGDDTDIGVLLGLGEHHGPSAVRWTLDALGDVGESWRMRFPAPYGERVVHGFPFSDQFTLPGKVRTGLCLDSRAMSAFLPRIGKFRHAKPLSWLLRNVHFGRDGFAVAAASNGKVMAFSGRRQSRATGLVAAMVVRRLAGMSPGVQHIENAVGTDFLPELADHGFNLDEYQTR
>NZ_CP016353.1|WP_091810018.1|4400272_4400899_-|M23-family-metallopeptidase
MAASIDMEYPFSGSWLVRNSPADRVPSHGTTLFATSYAIDFVPVGDTGRTAPVTLGSLLRPEAPEKFPGFGWPVSSPVEGIVVAVHDSEADHPAYRGLPSIGYALTQRRRAEAGWTALAGNHVLIESDGIVVALCHLQRGTAEVRPGQRVRIADVVGRCGNSGNSTEPHLHVQAVDSRDVEHADAVRLTFNGSLPRNGEIVVRESHAH
>NZ_CP016353.1|WP_091810017.1|4399849_4400239_-|hypothetical-protein
MSLQADEMILFRNTMRITEGHLEEFTAAVRDAVDFVERNAPQVMVQTFVDADRMLAYSYQMYPDSAAVLEHWRVSEAQIDNVSAHCTVVDFQVHGSPDERVLAGMRGMIDDGTAVVTSRIAGFVRPFAG
>NZ_CP016353.1|WP_091810015.1|4397831_4399730_+|hypothetical-protein
MQAEQIHNSTVNINAATPPEVKFGYARQLLHEGNAYLARELIRDVLKAGFTTGIVQFHWVLATLSTRSLRDLEPHEQRDLNRLLANQNTTGDDWARALQAIQALLEVQRKPGYDPSPAMAKLDALDERLQAQIRKHLQVVLTGAVKEEIWTRMRADAEREQFANNRENRVWAYFYPQPAAARVRTPDEPDVTTRDRLHAIAMSSLAVLAVTYLGWLVLEQPALLAAFVATIAAGYVAVANGLEWCRRVRLCNLRDRDYHTQRGVKWLPDKGFASEIDSAFEYYAHKYTHGDSHQEQWLASTRGIRTMRRNEIVELYREERISAEQVKWLIRYIVGDLRDRWKRGALMEHRERYRVARFTKIWFAAAVTVFLGTGGVVITAAAHIQPVFAAFAAVITVVSGSFALKQWLHITCEHLRFAEDTEEFARVKAERIAAHDRWRNKLKKARPAEKEMETWLNADTTLLLDETLRHYSLSWNDIITYSYLRTPKTGSKRSRRHRGPSRASQYDVRIWLITVDGVREVHSDLNFEKASFMGRSRTNFRFDTVSSVGVKTPDQLSYTLELTLNNGPARPITITDTGQQHHRPDENPTELSRTNLAATGFTHTLRVLEGIAAEGKGWISRHANTTGDRATL
>NZ_CP016353.1|WP_091810014.1|4396599_4397751_+|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase
MSRGTVVVLTALDSEYVAVRRRLSELRVHRHERGTRFEIGTLAEISGRIVLAQVGKGNQATAVLTERAIQRFDPAAVLFVGVAGALWDSTQLGDIVVATHVYAYHGGTSEDDGLKARPRAWEAPHGLSQLATHLSRTGCWAKNLPTDRPAPRVHFGPIAAGEVVQNSRLSAEAAWIRQHYNDAIAIEMEAAGLAQAGHLNNAPVAVVRGISDFADGGKTSEADARWQPHAVDNAAAFALHLAQELITEREQPTMNDPEPSLPRGSTHNTGTGQVGIQANQVFGSTVYFGGGPPSITPADLSSELRELRSSVDRSHANGTLDDPTYKDARTQLDTATSALESTSTPEGASTFVLALKRLRGLTSDIGEIVTKIAAIIAAVNGLS
>NZ_CP016353.1|WP_091810012.1|4395871_4396603_+|NUDIX-hydrolase
MPTHSWSPPPVLLAVDLVILTLRGGELHVLLVERGIEPFAGHQALPGGFLNNASEDIVAAAHRELYEEAGLDAGRLYLEQLGAYGAPGRDPRGRVVSVAYLAIAPGLPEPEPGTDAADADWAPVAAVMCGDLSVAFDHRQIVADGLERARDKLERFPLATAFCPERFTITDLQQVYEAVWGTRLDARNFARKVHALPGFIVAEPSTRRMTRGRPAQLFRAGPNTVLSPPLARPAGSMTHEGDV
>NZ_CP016353.1|WP_170140147.1|4395361_4395499_+|hypothetical-protein
MVEHIGDYPRDDLSFAALLILTVLAVAAATAAITRFGRRDLTTTT
>NZ_CP016353.1|WP_091810010.1|4394063_4395305_-|hypothetical-protein
MHRSDVVVRYTVVLAGAAVGIGGMTVLGLVLAGATFTGSLVHGAGLALIGLTFTALGLLTAQLAPSTTAAREFAAVVLGIALVLRVAGDAGAGLEWLRWLTPFGLVTNSAPFAANTVLPLAAGVPAVLTLVALAAFVADRRDLGAGLLRRHRSRRAPRRWLLGSAMAFAVFRSVRPCLMWTFAVSSFAMFLGGVSGSVIDFLAAQPRFAALAADAGFSGLDTISGFAAVIFSVLAVVAGFYAVSRMKAVATAEFTGRAVHLFALPLTRRRLVLAEVVVGASGIVLMLSTAAAAMWCGTFIAGEHLPLPETVAGALNVAPVSVLSLAAATLALGGLPRLVSLIGAVPTVGGFVLAAAAPSLGLPGWLAALSPFTYLTPVPQAPADWTALTVFSVTAAILVTLGAVAYERRDLAC
>NZ_CP016353.1|WP_091810008.1|4392490_4393885_-|DUF4389-domain-containing-protein
MTTPHRYPVTVEASLDADLSRWLWLVKWLLVLPHYLVLAVLWPVFCLLTVVAFVAILLTGRYLRGLFEFNVGIMRWSWRVHYYAYAALGTDRYPPFTIADVPWYPARLTVDYPARLSRGLVLVKWLLAIPHFLIVGLFAGGGLWLLGWRQTNDSTWAGGGLIGILVLVAGVVLLVKGRYPKPLYDFVLGLDRWVVRVGAYAALMTDEYPPFRLEMGGEAESPDTVPEPAPAARWTGGRIAAVVVGALLVLTSMGLLTGGGVALWADRAQRDPAGYLSASGTFSAPGYALTAERVAFGDNPAGWLGAGLGDVRIRVTATDPAEPVFLGIAAPGDAARYLAGTGYSTVRNLTGDSAPIVHNGGAPSERPEQAGIWVVQSSGPGTRTVTIRPAGGERTVVVLNADLARGVSVDAEAGATIPALPWIAAGALALGVVFLGAGAMLIGRAAHLAGREGADDSRNQPTKP
>NZ_CP016353.1|WP_091810022.1|4403835_4404192_-|hypothetical-protein
MSPKRGDDVAPPTVSDEWKIRYAKTEAIKGWQKLTNTAGNNLRTAWDILRTRPGQGVSNRHHQLKGGLATGSVQAKDDLPRWQIEVTGAGRVWYLIDAEARTVWLEAASVGHPKLTEG
>NZ_CP016353.1|WP_091810023.1|4404188_4404662_-|hypothetical-protein
MAAPEVTFSELVNRPVDTVKKLHGARALQVRRRDGEDLVLSTASRAAEEAEVTSATTKLFVAMMQKDDRVRTLATEVLPTVFPWVRFLPKPDVQAFVVELMDVLEAAESLGNPAPVAHVIAMWKNTAGVYADPEVLAVLKKRGDDLGEVAAPDSTTA
>NZ_CP016353.1|WP_091810025.1|4404838_4405795_+|hypothetical-protein
MTNGRRRVRVAGHHNERAGPRQPPKKRTKLVAILTTAGVAVGLATGILTLLDRTGATVNEAFTDPLAVNVRYTGADGATGSAVVVPSEITADPRKGGDIQTAIEHYANHGGYVPKRTVFDIRLTGLREAEVAVTRIRAVEVRHGPPVNGTYLLSPGQGTGDVVPVRLDLDHEATEIDARRMVPAEGEFGEPVDAGPYPGQDRGDLTLGKSENARIVVDTVARQRSAEFKIAIDTMVDGEPQSPIVVGTAGAGNTGEPFRITAVCEAGTPVTYRDGYIWTGGMARSPEQTIERMPPEILEGPGVGSPEHERERWCDGLS
>NZ_CP016353.1|WP_091810026.1|4405897_4406914_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MRTGSRRAARRRSIIAIMASGALLLGACGGQDEATPDAAAGGGGEGYPKTIEHAMGTTTIETKPQRVVAMDPSFADAALLLEADLVGYAQYRVDPDNPFPDYLGDIDGAVADSVNVGTTAEPDLEKVLELDADLIISAKVRHEAFYDQLSRFAPTVFSESTGPTWKENVVLLGDALGKKDKAEELVESYHQRAAAVGKEILAKQPDLTYSFVRFAGEDTARLYSSNSFIGEIMADMGIPRPEGAPDTEEEIFVPLSSEQILNADARLIMVSAYTPPGAEGEASKDQRADFEGNPLWGRLSGDVLAVDDEPFVLSVSIQGAHASITTLAEHFGVDPQLP
>NZ_CP016353.1|WP_091810028.1|4407035_4408091_+|iron-ABC-transporter-permease
MTLDTGTGHDLSGIGSTRSAVVGRSPWVTAGIPAAAVLAAVVASICLGSSPSTLAEVWHAIVTPTGTDMDVTIRELRWPRTLTGIAAGACLGVAGLLTQGHTRNAVADPGLLGINQGAALAIVAATFTFGGLSVYTQATLAFFGALLASVVVFLIGTAARHGATPITLVLSGAAVTALCGGVVTGLTLLDEASLDTLRFWQVGSLAARSNVIDSLWPFVLAGLLLAVLNIGALNTLALGEDVARSLGTSVLAARSTGIAAITLLAGCAVTMAGPIAFAGLVVPHLARAVAGGDYRRSLPAAAAIGVGLVLVADTAGRLIARPGELSVGVVLAVIGAPFFVLLARRRRMVTV
>NZ_CP016353.1|WP_091810029.1|4408087_4409170_+|iron-ABC-transporter-permease
MSPGADTPLAPARVLRAGPVSIMVRPRAVAVGVSLAVLCLLAAAVHLANGGTALPVDAVARALLGDDSNRLVYLAVTELRAPRTLAAIIAGACLAAAGALTQTVARNPLASPDILGVTAGSSLGAVSVVVLAGGGAAGLSGMAGNVSLPVAAFAGGVLAGALVYLLALSRSIDSYRLVLVGLGINGLAVSLTTWMLTLGDVTNAAQALTWMSGSLNGKDWPLVEPMAVLGAVLLAAALVLGRRSALLTLDDDVTTGLGVRVGLLRLAAFGLAALLASTGVVVAGPLVFVALASPQIARLITGSVTPPILPSALVGIVFVLIADTVAANALPVSLPAGVATAVLGGPYLIFLVLRYQRRLA
>NZ_CP016353.1|WP_091810031.1|4409166_4409967_+|ABC-transporter-ATP-binding-protein
MSRNGTTPTLRADNLTLGYDGADIITDLTFTVPAGRVTSIIGPNGCGKSTLLRGLGRLLRPRSGTVVLDGKPITAQSTRQVARRIGILPQSPAAPSGLTVADLVSRGRHPRQRWYEQFSILDEKALRHALESTGMAELAGALLEELSGGQRQRAWIAMILAQETDILLLDEPTTFLDLAHQVDLLELVVRMNREHDRTIVMVLHDISLAARYSDHLVAMKAGAIVTQGAPDQVVTTDLLHDVFGLRADVVTEPAEGRPHVIPLGSG
>NZ_CP016353.1|WP_110057688.1|4410128_4411352_+|glycosyltransferase-family-1-protein
MRVLLSTYGSRGDVEPLVGLAVRLRELGAKVRVCAPPDEDFARRLGDVDVSLVPVSQSARAWAKAAPPASGLPRHAAEVIAGQFEAITPVAEGCDVLMATGMMPAAAGALSVAELLGIPSVSVTFQQLTLPAPHREPLAYPGRPFPPEVTDNRVLWDLDARNIDALFGEALNTNRAVAGLPLVDNVRDYVVGDRPWLATDPVLDPWRETPDLDVVQTGAWILPDERPLPSDLVAFLDAGEPPVFVSFGSMPMHASGDAAEVAVEAVREQGRRIVIGRGWADLTPVDGDDDCFIVGEVNHQALFARVAAVVHHGGAGTTTTATHAGAPQVVVPQLADQPYWAGRVAELGIGVAHDGPVPARESLAAALKTALSPETRARATTVAATIRDDGATVAAKLLLDAAENHIG
>NZ_CP016353.1|WP_091810032.1|4411592_4412936_+|MHS-family-MFS-transporter
MSQASEQPKGMGRVVAASFMGTTIEYYDFFIYGTAAALVFPQIFFPALGPAAGTAASFATFGVAFLARPLGGLVFGQMGDRIGRKTTLVTTMLVMGIATVLIGLLPSGDTIGLFAPIALIVLRFLQGLAVGGEWSSAALFVVEHAPQGKRGWYSLAQTLGTTFGLLLATLTFLITGLTMSDASFLSWGWRVPFVLSALLVAVGLWVRLGVTDTPVFKDAMAKARDAKATKAPVRELFAKQGREVFLASGSVLMWLSFFYMGAVYLTNYGTAVLGLSKNSMLTIQFIAIAGCIAGQVIGARLSDKIGRRRILMLGNGSAVVWAFVLFPLVDSAVVWLVGVALTVTLFVVGLSNGSTTVFLPETFRTSYRSTGTGVSFNIGSVVAGAIPPIIAAPILASHGSIGLSIMLAVLAAVALVSVIFMRETSKNSLYEAHDEAKAPAATPPVTN
>NZ_CP016353.1|WP_091810034.1|4413000_4414218_-|FAD-dependent-monooxygenase
MIDNEVIIVGAGPVGLIAALGLAKRGIGVTVLDAAGDILDEPRGMTYHWAALAGLERLGVLADAMEIGYLKHDWSAQVFRTGERLSMDIGLLKDDVRHPYSLVLGQDALGRVVMRHLAKHACADIRWGHAVTGFDQDDTGVTVRVETGSGTREWRARWLVGADGARSIVRSGLGLGFEGMTWGERFVATNCRGRYEDHFVSGYLIDSEYGAVVHQITTEGLWRHTFAESLELPEEGIEKRMADYFRAVLPGTDFEHEILRWRHYRMHQRSAETYRVGRVLLAGDAAHVTNPTRGFGLVGGMFDAFTLTEALGAILRDGGDDALLDAYSEARRRVFWDYTTPISSDSKRLVFEPTRERLETFRTVAADPDKTRRYLLSGVALATPSLLGTMNVWETVGASPGLGDL

Crispr_ID: NZ_CP016353_10

• CRISPR_ID: NZ_CP016353_10
• CRISPR_location: 5327527-5327634
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP016353_10

Consensus_repeat	Method
CGTCTCGCGCGGGGCTCGCGGGCGC	CRISPRCasFinder

spacers of NZ_CP016353_10

>10.1|5327552|58|NZ_CP016353|CRISPRCasFinder
GCAGGCGGGCGGGCGCGGGCGCACGGGCGGGCGCACCGGCGGGCGCGCAGGCGGGCGG

CRISPR arrays and Neighbor proteins around NZ_CP016353_10

CRISPR arrays

The CRISPR arrays of NZ_CP016353_10

>merge|NZ_CP016353|10|5327527-5327634|CRISPRCasFinder
CGTCTCGCGCGGGGCTCGCGGGCGCGCAGGCGGGCGGGCGCGGGCGCACGGGCGGGCGCACCGGCGGGCGCGCAGGCGGGCGGGCGCTCGCGCGGGGCTCGCGGGCGC

>NZ_CP016353|10|9|5327527-5327634|CRISPRCasFinder
CGTCTCGCGCGGGGCTCGCGGGCGC	GCAGGCGGGCGGGCGCGGGCGCACGGGCGGGCGCACCGGCGGGCGCGCAGGCGGGCGG
GCGCTCGCGCGGGGCTCGCGGGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091807225.1|5334167_5335619_+|neutral-zinc-metallopeptidase	unknown	unknown	gnl|CDD|225203
NZ_CP016353.1|WP_091807243.1|5320607_5321513_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|236600
NZ_CP016353.1|WP_091807223.1|5335677_5336646_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|225660
NZ_CP016353.1|WP_091807219.1|5337198_5338095_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176106
NZ_CP016353.1|WP_091807242.1|5323236_5323617_+|VOC-family-protein	unknown	unknown	gnl|CDD|380093
NZ_CP016353.1|WP_091807221.1|5336724_5337126_-|RidA-family-protein	unknown	unknown	gnl|CDD|100011
NZ_CP016353.1|WP_091807228.1|5330661_5331483_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224044
NZ_CP016353.1|WP_091807234.1|5327646_5328843_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|380115
NZ_CP016353.1|WP_094168520.1|5321968_5322190_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091807230.1|5329828_5330608_-|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|235632
NZ_CP016353.1|WP_091807237.1|5325727_5326135_-|cold-shock-domain-containing-protein	unknown	unknown	gnl|CDD|239905
NZ_CP016353.1|WP_091807504.1|5322366_5323083_+|VOC-family-protein	unknown	unknown	gnl|CDD|319911
NZ_CP016353.1|WP_091807240.1|5323632_5324373_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP016353.1|WP_091807232.1|5328843_5329827_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP016353.1|WP_091807235.1|5326262_5326958_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_CP016353.1|WP_091807217.1|5338058_5338607_-|acetyltransferase	unknown	unknown	gnl|CDD|379237
NZ_CP016353.1|WP_091807238.1|5324503_5325619_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224172
NZ_CP016353.1|WP_091807227.1|5331523_5334091_-|alpha-glucan-family-phosphorylase	unknown	unknown	gnl|CDD|340852
NZ_CP016353.1|WP_091807247.1|5319686_5320118_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133388
NZ_CP016353.1|WP_176879786.1|5320141_5320459_+|thioredoxin	unknown	unknown	gnl|CDD|200072

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091807225.1|5334167_5335619_+|neutral-zinc-metallopeptidase	gnl|CDD|225203	COG2321, COG2321, Predicted metalloprotease [General function prediction only].	2.74144e-13
NZ_CP016353.1|WP_091807243.1|5320607_5321513_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	1.12382e-72
NZ_CP016353.1|WP_091807223.1|5335677_5336646_-|tetratricopeptide-repeat-protein	gnl|CDD|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	9.17405e-69
NZ_CP016353.1|WP_091807219.1|5337198_5338095_+|LysR-family-transcriptional-regulator	gnl|CDD|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.05733e-74
NZ_CP016353.1|WP_091807242.1|5323236_5323617_+|VOC-family-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.52746e-28
NZ_CP016353.1|WP_091807221.1|5336724_5337126_-|RidA-family-protein	gnl|CDD|100011	cd06154, YjgF_YER057c_UK114_like_6, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	5.54272e-60
NZ_CP016353.1|WP_091807228.1|5330661_5331483_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.11769e-100
NZ_CP016353.1|WP_091807237.1|5325727_5326135_-|cold-shock-domain-containing-protein	gnl|CDD|239905	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription.	1.53267e-22
NZ_CP016353.1|WP_091807230.1|5329828_5330608_-|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|235632	PRK05869, PRK05869, enoyl-CoA hydratase; Validated.	6.60211e-70
NZ_CP016353.1|WP_091807234.1|5327646_5328843_-|SAM-dependent-methyltransferase	gnl|CDD|380115	pfam18096, Thump_like, THUMP domain-like. This is a domain of unknown function found in bacteria.	4.18949e-18
NZ_CP016353.1|WP_091807504.1|5322366_5323083_+|VOC-family-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	3.24202e-22
NZ_CP016353.1|WP_091807240.1|5323632_5324373_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	5.80634e-13
NZ_CP016353.1|WP_091807232.1|5328843_5329827_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.11946e-26
NZ_CP016353.1|WP_091807235.1|5326262_5326958_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.05506e-11
NZ_CP016353.1|WP_091807217.1|5338058_5338607_-|acetyltransferase	gnl|CDD|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.23612e-24
NZ_CP016353.1|WP_091807238.1|5324503_5325619_+|FAD-dependent-oxidoreductase	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	3.07685e-73
NZ_CP016353.1|WP_091807227.1|5331523_5334091_-|alpha-glucan-family-phosphorylase	gnl|CDD|340852	cd04299, GT35_Glycogen_Phosphorylase-like, proteins similar to glycogen phosphorylase. This family is most closely related to the oligosaccharide phosphorylase domain family and other unidentified sequences. Oligosaccharide phosphorylase catalyzes the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism.	0
NZ_CP016353.1|WP_091807247.1|5319686_5320118_+|MerR-family-transcriptional-regulator	gnl|CDD|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	8.52111e-38
NZ_CP016353.1|WP_176879786.1|5320141_5320459_+|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.91928e-41

Protein sequences

>NZ_CP016353.1|WP_091807235.1|5326262_5326958_+|PadR-family-transcriptional-regulator
MVSRTRSNPLALAVLTLLHERPMHPYEMSSTLRERRKEDSIKLNYGSLYSVVDSLVKRGLIAPHETVRDGKRPERTVYVITESGTAEMTEWLGDLLGRPAKEFTQFEAALSLMAIFGPDEVLRLLDIRLGTLRAQETAYYAMLAGMPGNFPRIFLIESEFRAKLLRTEIEFVDDLAKELREGTFHGMDLWLRMQRLRESGASPAELEQELTKEFKEELEWINKLSKETPPQ
>NZ_CP016353.1|WP_091807237.1|5325727_5326135_-|cold-shock-domain-containing-protein
MVTGKVVRFDESKGYGFVTPDTGGEDVFVHVNDLDFDKRLLMPGAVVEFEVEDGERGLKASRVRIVGRHTGDTAGQQPASAHDDEGLGDVLTVREFLEEITEALLDAAPGATAEQILRIRQRLVQVAHGHGWIDA
>NZ_CP016353.1|WP_091807238.1|5324503_5325619_+|FAD-dependent-oxidoreductase
MTAHIVVLGAGYSGLLTAKLIAKRTDARVTLVNARDRFVERVRLHQLAAGQELEDLPITGLLEGSSAAFKQDRVTGIVPDMRTITLAEGEPLTYDILVYALGSTADLESVPGAAEHAFTVTSAEQAAALRTRLENSKTVAVVGGGLTGIEAATEIAETKPGLKVKLVTGGVFGEALSEKGGKHLRKVFGRLGIDIVDNAVVKEVAAEGVVLADGKHLEADTVVWTTGFRVPELARAAGLECDASGRLAVDETLRSVSHPDVYGVGDAAAARMKTGQELRMACATGLPSAMQLARSISGALVGKPGKPLRFRYFNQCISLGRRDALVQFVRADDTPVSAVLTGRFAARYKETIVRSTVWAQRHPVLAAAVLP
>NZ_CP016353.1|WP_091807240.1|5323632_5324373_-|class-I-SAM-dependent-methyltransferase
MVDHQFADERLAALYDEFHPWDPRGDFGFYLPMVMSAEAVLDVGCGTGMLLHRAREAGHKGRLCGLDPGEGMLRRARVRSDVEWIDGDLSSTAFRGEFDLVVMSGHAFQVFVTDEQLRSSLSAIRDALTGEGRFAFETRNPAARAWEGWTPENASEVIGADGAVVRMSHQVERPVIDDIVRFTTTYSSPGWDADEHSHSSLRFLDVPSLSGFLSEAGLAVEHQYGDWDGRPVTETGIEIITVAKRV
>NZ_CP016353.1|WP_091807242.1|5323236_5323617_+|VOC-family-protein
MACRISELVLGCRDPEALARFWCEVLDFVVLDREGGEMLEIGPREGFGGPQPTIILSRRDEPEKGKARLHIDVNATDRDQEAELERLLKLGARPADIGQTGEEEWHVLADPEGNEFCLLKARIAPL
>NZ_CP016353.1|WP_091807504.1|5322366_5323083_+|VOC-family-protein
MPSSTTRDRLFPFCWLDVKSHDPAALERFFVSTLGWEFAVDEQDWRKATVISVAGHRIGGVSDLANPVYPEETPAHVAFYLTVDDVEARTEAALALGASLVVGPFEAGDQGRMSTLVDPWGAAFSLWQPLAFSGWSVPTGVNGAPAALRLSCTDPLASRRFYENALATTLPPEFFVARPGGESRPQWELLVEVDDLSTVRTRIGTLGGVADELADGNRPGLRMRTDEGIAIRLRSLDS
>NZ_CP016353.1|WP_094168520.1|5321968_5322190_-|hypothetical-protein
MARGYGFGARTVMVGRKATVSELARPFSPTGVSIVTERVEPLERGREIGLLPGAGVSATSPRYRGPALGDPGP
>NZ_CP016353.1|WP_091807243.1|5320607_5321513_-|sigma-70-family-RNA-polymerase-sigma-factor
MDEGDRLAAVFEEHRARLRVIAYRMLGSASEADDAVQETWLRLSRSDTGDVANLAGWLTTVVSRVCIDVLRSRQVRREDLVGHELPESAEGDEHRVEPEGEALLADAVGRALLVVLGTLRPAERVAFVLHDMFALPFDEIAPIVARSPVATKKLASRARQRLRGTTTAPDAEIARHRAIVEAFLVASRGGDLDTLVELLDPDVVRHADRSALPAGAATVVRGASTVARETRVFAARAAIAEPALIDGAVGVVIAPNGLLRLVLTVTIKEDRITEIEVIADEERLRNLRITVPGGWRRPGVS
>NZ_CP016353.1|WP_176879786.1|5320141_5320459_+|thioredoxin
MTVVTDDTFERDVLRHEKPVLVDFWAEWCPPCRILAPILAEIAHERADVLTIRKLNTDENPRTTRDYQVMSAPTLMLFREGSPIRMLVGSRPKTRLLAELDDALR
>NZ_CP016353.1|WP_091807247.1|5319686_5320118_+|MerR-family-transcriptional-regulator
MRIGELAKMAGTTPRALRFYEAQGLLGARRAANGYREYDDQDLRLLREILALQEVGLSLDDTKPFVECLRAGNESGDSCTDSIEVYERKLAEVDACLDRLGSLRASLLSKLAGALARQPGPCQVADHPGDTGEIASTNPRESS
>NZ_CP016353.1|WP_091807234.1|5327646_5328843_-|SAM-dependent-methyltransferase
MPYAFSLDDVAFLKSGPGEEALSFCDRLPLTDASRIADVASARKAVGDRYAAVLETVVLRRKAHGKMDNAERWLFEGDALQQASAAPVARHRARRLADRRVHDVTCSIGADLVELARTASACAGSDLDAVRLAMAAHNCAVEEVAPELAVADALRPVSGDAVVVADPARRDASGRRMWRGTDFVPSLDELAAVYVDRDLVVKTAPGINVETVPWAREIELVSLEGQVREACLWSEGLATVSRRASVLKADGTQWTITDAESDDAGAGEPGEWIIDPDGAVVRAGLVRHYAARHGLWQLDERIAYLTGDTPPPGVRAFRVREFETYGEKTLRAALRRHDIGRVEILVRGLDVDPNALRRRLKPKGEGEASVVLTRIGRTPMAFLCEARRIPATPPEPTE
>NZ_CP016353.1|WP_091807232.1|5328843_5329827_-|class-I-SAM-dependent-methyltransferase
MTQSPATDPAPNPHASEDEVRAAYSDPKLANVLYHDWEAGTYDEKWSISYDERCISYATDVFDAVAGERGQPYATAMELGSGTGFFLLNLMQGGVVKKGSVTDLSPGMVEVALRNADNLGLDVDGRVADAERIPYDDNTFDLVVGHAVLHHIPDVQSAFREVLRVLKPGGRFVFAGEPTKIGDFYARRLGRVTWWLTTNITKLPALAGWRRPQEELDESSRAAALEAVVDLHTFDPSELERWALRAGAVDVKAVTDEFSAALVGWPIRTFEAAVPQEKLTVRWRLFAYRAWLRLSALDKKVLAKVLPRELFYNVMITGTKPADPVEL
>NZ_CP016353.1|WP_091807230.1|5329828_5330608_-|enoyl-CoA-hydratase/isomerase-family-protein
MGEFVRLEVADGVGTIRLDRAPVNALNNQVQAELGEAAREATDRADVRAVILYGGEKTFAGGADIKEMAAKSYAEISTFGTALTNSLTALAEIPKPTVAAVTGYALGGGLELALTADRRVAGDNVKVGQPEIQLGIIPGAGGTQRLARLIGPSKAKDLIYTGRFVKAEEALALGIVDEVVAPDDVYSVAHKWAAQFANGPALALRAAKAAIDGGLDLDLRNGLKLETSLFTALWATEDQAGGMASFIENGPGKATFEGK
>NZ_CP016353.1|WP_091807228.1|5330661_5331483_-|ABC-transporter-ATP-binding-protein
MGTVNEVAVQDNLDDLVIHLSGVEVRRGGNKLLADLDWAVELDERWVVLGPNGAGKTTLLKLAAAELHPSDGAVHVLGERLGKVDVFELRTRVGFTSAAVNGRVPAEERVRDVVLSAGYAVLGRWRESYDTLDTARADELLRALGIEHLAERTYGTLSEGERKRTLIARALMTDPELLLLDEPAAGLDLGGREDLVARLSTLAMDPDAPAMVLVTHHVEEIPPGFTHALLLADGYSVAAGLVDDVLTSENLSKAFGQDLMLQRSGDRYFARRR
>NZ_CP016353.1|WP_091807227.1|5331523_5334091_-|alpha-glucan-family-phosphorylase
MRAVRRFTVHARIPDQLAGLTALATNLRWTWHPPTRDLFASMDDALFRRVRDPLRMLTVIPARKLEELASDAGFLARTRDAVDDLERYLSEPRWYQRRAAEDAGTTDHDERFPSAVAYFSMEFGVHEALPNYSGGLGVLAGDHLKAASDLGVPVVGVGPLYRAGYFRQSLSLDGWQIEHYPVIDPSGLPLELLTEPSGEPVLVRVAMPGGRELQAQIWEARVGRVPLLLLDTDVEGNDEDLRGVTDRLYGGDADHRIRQEILAGIGGMRAVRRYCELTGHPQPEVFHTNEGHAGFLGLERAREILKGSDLSFDDVLSAVRAGTVFTTHTPVSAGIDRFPVDLVQHYFGDGRLLPEIDPRRVLALGAEDNPNMFNMAHMGLRLAQRANGVSALHGRVSRRMFGKLWPGFDTEEVPVRSVTNGVHGPTWVAREMSALLGGSDEEWGHDGDGGSGKAGVTDEELWALRRELRGNLVAEVRRRARDAWLQRGASALELGWTERIFNPDVLTVGFARRVPTYKRLTLMLRDPERLRALLLDEQRPIQFVVAGKSHPADEGGKALIQQIVRFVDDPEVRQRIVFLPDYGMSMARYLYRGCDVWLNNPTRPLEACGTSGMKAALNGGLNLSTMDGWWDEYYDGSNGWAIPTADGVTDPLQRDDLEADALYDLLGQQIAPLFYERDAGGVPKGWMSMVWHTLRTLGPRVQASRMVREYVDSYYVPAATTVAAASDEHYAGSRSLAAYRTKLDLYWGRVRVLDTELTYDGTDSLVVGKEVRVRAGIDLAGLDESDVDVQVVVGRVGDTDDLHDVETVPMWPSGRGGYEATLRLPHAGALGYTVRVLPKHPLLAGPAELGKVVLA
>NZ_CP016353.1|WP_091807225.1|5334167_5335619_+|neutral-zinc-metallopeptidase
MNRTGGRGARLRALTATIGVFALLASACGTETQGRPLTSGDIAGLPVTHFESGLKPDAPKPDLDVQNADNGPEDTVAIAAIADVSAYWAQELPAHFSMEFEPVKKLLSYDPNEPDIEVCGATTADAAMNAFYCPSEDLVAWDRGMLLPLLKQRFGTMSIVTVLGHEFGHAIQYRLGDKAGVDDSTSTIVKEQQADCFTGSYFRWMAEGKSEYFDVSTSEGLNQVLASLFFIRDEAGQSAQEQGAHGTAFDRTYAFQLGFEDGAKECAAINQENIDERITEVPFAPDDVGQGDVMIDEAIVATLQENLDQTFAGAGVEGPRIVADGGSCPDGVSTPPASYCADTNTVSIDLPALAELGQPVDREAEFQGEEGNGGLGDFAAFSEIASRYVQGIQNGVGASLDSPNAGMRTACLVGAWAGATNTEGSTLRLSPGDLDEAIAELLRPHSLLAADVNGHPVASGFARVEALRQGYFGGSEPCTQNYG
>NZ_CP016353.1|WP_091807223.1|5335677_5336646_-|tetratricopeptide-repeat-protein
MTQPRGSAANSPALSAALSGAVDLSGLKARADASRPRPDGSGDQATAGGPPSEGAVIDVTEATFQAEVVERSLQTLVVVDLWAEWCGPCKQLSPVLERLAAESGGAWVLAKVDVDANPRISQLFGVQSIPTVVAIAGGQPVDAFSGAQPEPQIRQWLGQLLDALRDKLPGINAAEQQAGGEPEEEQEDPRFTEAEDALDRGDFAEAEAAYQRILDAEPGNELAKAALVQVRFSARASETDESAVAKAEADPADLDAQLAAADYEVAQRDPSAGFARLIGVIRKTSGDDRNKVREHLVGLFDLFDPADELVIKARRDLASALF
>NZ_CP016353.1|WP_091807221.1|5336724_5337126_-|RidA-family-protein
MTARHAILSGSTFEEQIGYARAVVDGDWVHVSGTTGFDYTTMTISDDVVEQAEQCLRNIESALSEAKCGFADVVRVRYLLPERADFEPCWPVLRRRFGTVRPAATMLTCGLADPRMKIEIEVYARRTVTDRPA
>NZ_CP016353.1|WP_091807219.1|5337198_5338095_+|LysR-family-transcriptional-regulator
MERPEVPLAQLHSFVVLAEEAHFGRAADRLGIAQPPLSQQIRRLEDKVGHALFRREPGRLTLTPAGREFLPAAVSALAGLADGLAAARAVGTGEAGRLRIGFAASLALTVLPGLLRGFRQRFPGVSLDIREMTTAPQIVALLDKKIDIGLLREPPREPELEFRTVLDEPFVAVLPKGHPLAATRGVALEHLAELPFVLLPRAAGPGLYDQIVAMCASAGFTPRIGQHAVEWQTVCALVETGLGVSLAPASIRRIRLTGVAYRRIEPDTTRTRVAIAWRGDDDNPLLTQLLATLGRSIR
>NZ_CP016353.1|WP_091807217.1|5338058_5338607_-|acetyltransferase
MINWRRLTEQDFPLLREWLRQPHVARWWNHETSAEAVERDFGAAARGEEPSEDLLVFLDDQPVGLVQRIRYGDYPDYRKELAPILDVPGAAVCIDYLIGDPRRTGIGLGPRVIGAIVEATWEDHPDSPSVVVPVSAANRASWRALEKAGLRRVAEGELDPDNPVDGRDHYIYLIDRPSVASS

Crispr_ID: NZ_CP016353_11

• CRISPR_ID: NZ_CP016353_11
• CRISPR_location: 6222332-6222725
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP016353_11

Consensus_repeat	Method
GGACCACCCCCGCGTGCGCGGGGAGCAC	PILER-CR
GTGCTCCCCGCGCACGCGGGGGTGGTCC	CRISPRCasFinder
CTCCCCGCGCACGCGGGGGTGGTCC	CRT

spacers of NZ_CP016353_11

>11.1|6222360|33|NZ_CP016353|PILER-CR,CRISPRCasFinder
AGGCTCGGACTCGACATCCAGCACCCATGCCAC
>11.2|6222421|33|NZ_CP016353|PILER-CR,CRISPRCasFinder
CACTGAGACTCAATGTTGACGGGACCGGCCTGG
>11.3|6222482|39|NZ_CP016353|PILER-CR
ACGTCACGACCGGAGCGGTGTCGCCGAGTTCGAGTGCTC
>11.4|6222549|32|NZ_CP016353|PILER-CR
CATCAGCCAGCGGATGATCGACCCGATGGTCT
>11.5|6222609|33|NZ_CP016353|PILER-CR
CCAGTGCCGCCAAACCGGGCGGGCGGACATGAT
>11.6|6222482|34|NZ_CP016353|CRISPRCasFinder
ACGTCACGACCGGAGCGGTGTCGCCGAGTTCGAG
>11.7|6222544|32|NZ_CP016353|CRISPRCasFinder
CATCAGCCAGCGGATGATCGACCCGATGGTCT
>11.8|6222604|33|NZ_CP016353|CRISPRCasFinder
CCAGTGCCGCCAAACCGGGCGGGCGGACATGAT
>11.9|6222665|33|NZ_CP016353|CRISPRCasFinder
GGTTCTGATGATGTCCTTGACAGCAAGGCACAG
>11.10|6222360|36|NZ_CP016353|CRT
AGGCTCGGACTCGACATCCAGCACCCATGCCACGTG
>11.11|6222421|36|NZ_CP016353|CRT
CACTGAGACTCAATGTTGACGGGACCGGCCTGGGTG
>11.12|6222482|37|NZ_CP016353|CRT
ACGTCACGACCGGAGCGGTGTCGCCGAGTTCGAGTGC
>11.13|6222544|35|NZ_CP016353|CRT
CATCAGCCAGCGGATGATCGACCCGATGGTCTGTG
>11.14|6222604|36|NZ_CP016353|CRT
CCAGTGCCGCCAAACCGGGCGGGCGGACATGATGTG
>11.15|6222665|36|NZ_CP016353|CRT
GGTTCTGATGATGTCCTTGACAGCAAGGCACAGGTG

CRISPR arrays and Neighbor proteins around NZ_CP016353_11

CRISPR arrays

The CRISPR arrays of NZ_CP016353_11

>merge|NZ_CP016353|11|6222332-6222725|PILER-CR,CRISPRCasFinder,CRT
GTACTCCCGGCGCACGCGGGGGTGGTCCAGGCTCGGACTCGACATCCAGCACCCATGCCACGTGCTCCCCGCGCACGCGGGGGTGGTCCCACTGAGACTCAATGTTGACGGGACCGGCCTGGGTGCTCCCCGCGCACGCGGGGGTGGTCCACGTCACGACCGGAGCGGTGTCGCCGAGTTCGAGTGCTCCCCCGCGCACGCGGGGGTGGTCCCATCAGCCAGCGGATGATCGACCCGATGGTCTGTGCTCCCCGCGCACGCGGGGGTGGTCCCCAGTGCCGCCAAACCGGGCGGGCGGACATGATGTGCTCCCCGCGCACGCGGGGGTGGTCCGGTTCTGATGATGTCCTTGACAGCAAGGCACAGGTGCTCCCCGCGCACGCGGGGTGGTCCG

>NZ_CP016353|11|6|6222332-6222664|PILER-CR
GTACTCCCGGCGCACGCGGGGGTGGTCC	AGGCTCGGACTCGACATCCAGCACCCATGCCAC
GTGCTCCCCGCGCACGCGGGGGTGGTCC	CACTGAGACTCAATGTTGACGGGACCGGCCTGG
GTGCTCCCCGCGCACGCGGGGGTGGTCC	ACGTCACGACCGGAGCGGTGTCGCCGAGTTCGAGTGCTC
CCCCGCGCACGCGGGGGTGGTCCCATCA	GCCAGCGGATGATCGACCCGATGGTCTGTGCT
CCCCGCGCACGCGGGGGTGGTCCCCAGT	GCCGCCAAACCGGGCGGGCGGACATGATGTGCT
CCCCGCGCACGCGGGGGTGGTCC

>NZ_CP016353|11|10|6222332-6222725|CRISPRCasFinder
GTACTCCCGGCGCACGCGGGGGTGGTCC	AGGCTCGGACTCGACATCCAGCACCCATGCCAC
GTGCTCCCCGCGCACGCGGGGGTGGTCC	CACTGAGACTCAATGTTGACGGGACCGGCCTGG
GTGCTCCCCGCGCACGCGGGGGTGGTCC	ACGTCACGACCGGAGCGGTGTCGCCGAGTTCGAG
TGCTCCCCCGCGCACGCGGGGGTGGTCC	CATCAGCCAGCGGATGATCGACCCGATGGTCT
GTGCTCCCCGCGCACGCGGGGGTGGTCC	CCAGTGCCGCCAAACCGGGCGGGCGGACATGAT
GTGCTCCCCGCGCACGCGGGGGTGGTCC	GGTTCTGATGATGTCCTTGACAGCAAGGCACAG
GTGCTCCCCGCGCACGCGGGGTGGTCCG

>NZ_CP016353|11|5|6222335-6222725|CRT
CTCCCGGCGCACGCGGGGGTGGTCC	AGGCTCGGACTCGACATCCAGCACCCATGCCACGTG
CTCCCCGCGCACGCGGGGGTGGTCC	CACTGAGACTCAATGTTGACGGGACCGGCCTGGGTG
CTCCCCGCGCACGCGGGGGTGGTCC	ACGTCACGACCGGAGCGGTGTCGCCGAGTTCGAGTGC
TCCCCCGCGCACGCGGGGGTGGTCC	CATCAGCCAGCGGATGATCGACCCGATGGTCTGTG
CTCCCCGCGCACGCGGGGGTGGTCC	CCAGTGCCGCCAAACCGGGCGGGCGGACATGATGTG
CTCCCCGCGCACGCGGGGGTGGTCC	GGTTCTGATGATGTCCTTGACAGCAAGGCACAGGTG
CTCCCCGCGCACGCGGGGTGGTCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091803088.1|6215123_6215996_+|PaaX-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225864
NZ_CP016353.1|WP_091803069.1|6224702_6226154_+|trehalose-6-phosphate-synthase	unknown	unknown	gnl|CDD|340820
NZ_CP016353.1|WP_091803086.1|6216249_6216678_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091803066.1|6228722_6230096_-|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NZ_CP016353.1|WP_091803052.1|6233320_6234703_+|cysteine--tRNA-ligase	unknown	unknown	gnl|CDD|234705
NZ_CP016353.1|WP_170140169.1|6217973_6218507_-|TIGR03086-family-protein	unknown	unknown	gnl|CDD|274424
NZ_CP016353.1|WP_091803063.1|6230125_6230659_-|copper-chaperone-PCu(A)C	unknown	unknown	gnl|CDD|377298
NZ_CP016353.1|WP_091803075.1|6219883_6221506_-|amidohydrolase	unknown	unknown	gnl|CDD|224490
NZ_CP016353.1|WP_170140168.1|6221813_6222191_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091803083.1|6216965_6218033_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|236196
NZ_CP016353.1|WP_009156479.1|6230992_6231484_+|CarD-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224248
NZ_CP016353.1|WP_091803058.1|6232133_6232607_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|178851
NZ_CP016353.1|WP_091803091.1|6214503_6214824_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP016353.1|WP_091803869.1|6226190_6228719_+|trehalose-phosphatase	unknown	unknown	gnl|CDD|225922
NZ_CP016353.1|WP_091803875.1|6211882_6212611_-|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NZ_CP016353.1|WP_091803055.1|6232617_6233304_+|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|274056
NZ_CP016353.1|WP_091803094.1|6212707_6214507_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP016353.1|WP_091803061.1|6231498_6232137_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
NZ_CP016353.1|WP_091803072.1|6223160_6224678_+|threonine/serine-exporter-family-protein	unknown	unknown	gnl|CDD|377697
NZ_CP016353.1|WP_091803078.1|6218660_6219839_+|exo-alpha-sialidase	unknown	unknown	gnl|CDD|271234

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091803088.1|6215123_6215996_+|PaaX-family-transcriptional-regulator	gnl|CDD|225864	COG3327, PaaX, Phenylacetic acid-responsive transcriptional repressor [Transcription].	8.46199e-47
NZ_CP016353.1|WP_091803069.1|6224702_6226154_+|trehalose-6-phosphate-synthase	gnl|CDD|340820	cd03788, GT20_TPS, trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.	0
NZ_CP016353.1|WP_091803066.1|6228722_6230096_-|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP016353.1|WP_091803052.1|6233320_6234703_+|cysteine--tRNA-ligase	gnl|CDD|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NZ_CP016353.1|WP_091803869.1|6226190_6228719_+|trehalose-phosphatase	gnl|CDD|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	2.83954e-83
NZ_CP016353.1|WP_091803063.1|6230125_6230659_-|copper-chaperone-PCu(A)C	gnl|CDD|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	6.48155e-10
NZ_CP016353.1|WP_091803075.1|6219883_6221506_-|amidohydrolase	gnl|CDD|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	2.91318e-138
NZ_CP016353.1|WP_091803083.1|6216965_6218033_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|236196	PRK08241, PRK08241, RNA polymerase subunit sigma-70.	1.20779e-163
NZ_CP016353.1|WP_009156479.1|6230992_6231484_+|CarD-family-transcriptional-regulator	gnl|CDD|224248	COG1329, COG1329, Transcriptional regulators, similar to M. xanthus CarD [Transcription].	2.68888e-70
NZ_CP016353.1|WP_091803058.1|6232133_6232607_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	5.47581e-73
NZ_CP016353.1|WP_091803091.1|6214503_6214824_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	3.41034e-15
NZ_CP016353.1|WP_170140169.1|6217973_6218507_-|TIGR03086-family-protein	gnl|CDD|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	2.16088e-17
NZ_CP016353.1|WP_091803875.1|6211882_6212611_-|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	2.89482e-48
NZ_CP016353.1|WP_091803055.1|6232617_6233304_+|HAD-IA-family-hydrolase	gnl|CDD|274056	TIGR02252, Rhythmically_expressed_gene_2_protein, REG-2-like, HAD superfamily (subfamily IA) hydrolase. This family of proteins includes uncharacterized sequences from eukaryotes, cyanobacteria and Leptospira as well as the DREG-2 protein from Drosophila melanogaster which has been identified as a rhythmically (diurnally) regulated gene. This family is a member of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The superfamily is defined by the presence of three short catalytic motifs. The subfamilies are defined based on the location and the observed or predicted fold of a so-called 'capping domain', or the absence of such a domain. This family is a member of subfamily 1A in which the cap domain consists of a predicted alpha helical bundle found in between the first and second catalytic motifs. A distinctive feature of this family is a conserved tandem pair of tryptophan residues in the cap domain. The most divergent sequences included within the scope of this model are from plants and have "FW" at this position instead. Most likely, these sequences, like the vast majority of HAD sequences, represent phosphatase enzymes.	7.58086e-25
NZ_CP016353.1|WP_091803094.1|6212707_6214507_+|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	7.37899e-33
NZ_CP016353.1|WP_091803061.1|6231498_6232137_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	6.17726e-40
NZ_CP016353.1|WP_091803072.1|6223160_6224678_+|threonine/serine-exporter-family-protein	gnl|CDD|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	2.27139e-64
NZ_CP016353.1|WP_091803078.1|6218660_6219839_+|exo-alpha-sialidase	gnl|CDD|271234	cd15482, Sialidase_non-viral, Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.	1.1753e-88

Protein sequences

>NZ_CP016353.1|WP_170140168.1|6221813_6222191_+|hypothetical-protein
MSQEPDDLAAAVAALQTEVADLRTHLQRVAKDAAAAQVLARGADRDVADLTSELRDFRTHNTNLHNATREDLRETRQELRELRESTNAGFMEMRGKLDATAAGQAQIAELLTTLIERGDRNDAAD
>NZ_CP016353.1|WP_091803075.1|6219883_6221506_-|amidohydrolase
MLDLLLRDVRALTMTGEHGFAHTVGVLGGRIVGVDDDVEGLSATTVFDGEGAVLTPGFSDVHNHMVWYGLSLAEIDLSGCRSHQEVYDAVARRASGMPSDAWVIGSGYDDFVLGGHPGRAELDRAGGGRPVWLKHRSAHMCVASTAILAEAGVLDGSATVPEGGVVSKDEAGEPTGLLAEQAQQLVDALVKPYPVEELADAIARAGKAYVAEGLTHVTEAGIGGGWIGHSPAEAAAYQLARRRGDLPLRVELMPASEVLHPLHGNAFGLDLGLHTGFGDDFLRIGPMKIFTDGALSSRTAAVSEPFHGHGGVGVLQDDPVVLRDRIVAAHKGGWRVAAHAIGDRAIDLALDAFAEAQRQLPRAGVRHRIEHAAMVRPEQLARMAELNIIPVPQARFLYEIGDTMAEAVGEERIPWLYRHRSFVDAGLRVPGSSDRPCVSRGAPLSSMRSMVERTSKAGVVLSPDERVDATEALRAYTTHAAWTACQENERGSIRKGAFADFVLLDDDPTTVPSAAIDDIEVLATFVAGQPVYGAEKIRGE
>NZ_CP016353.1|WP_091803078.1|6218660_6219839_+|exo-alpha-sialidase
MSAMSRRTVLSLAAATAAGLAVAAPASAAMASRATSIPYRSGTEGYHTFRIPALVRTRTGQLLAFAEGRLESAGDSGAIEVVLRRSTDGGRTWGPLAVISRNGDATAGNPSPVVLADGTIVLVTTRNGRVTEEEIMSGTVSDEDSRRVFVQHSFDDGLTFTEAREITAEAKEANWRWYATGPCHAIVLRGGRYAGRIVVPANHSSAPPAGSPDVGTEQKYYGGHCLLSDDGGRSWRIGFVDDRNDGHIAANETTVAELPDGTLYFNSRDHGTSPGERVDAYSGDGGATLVAPYREQPTIVGPRVQGSVLQASHPKTLLFSGPSNPDSRRSMSIRVSADGGRNWREAYTVSEAHAAYSDLVEIERGTIGLLYETGAANSSETIAFHRFATPRD
>NZ_CP016353.1|WP_170140169.1|6217973_6218507_-|TIGR03086-family-protein
MVWVLGRSVDYLLGALRFARGAAPSSPTPCAGWDLRTLLGHLDDSLDALAEAAGRGRVALEAEPGSGSSVDGLRERARALPPAWSGVSEVTIGGVPVEPDVVLAAGSIELAVHGWDVATACGVRGAMPDDLALALWQVAPTLVTKADRPWRFAEPVPVSAGSGTGDRLLAFLGRVPL
>NZ_CP016353.1|WP_091803083.1|6216965_6218033_+|sigma-70-family-RNA-polymerase-sigma-factor
METTGSERDRTMANTTVDQEFLRQADPFRRELLAHCYRMLGSAHDAEDLVQETYLRAWRAYDRFEGRSSLRTWLHRIATTTCLTALENRKRRPMPSGLGNGSSDPSGDLAERHDIRWLEPLPDPQTTEDDPASIVTERESVRLAFVAALQHLPERQRAVLILRDVLKWRAAEVADTVGISTAAVNSTLQRARAQLAEIAPHLDTVAEPDSSQQRELLDRYVSAFERKDVTELIALFTADIVWEMPPYASWYQGRTDVAHHLTHRCPAQPGKVLILPLRANGQPTFAMYLLDEKTGEYNAFTVQVLTVTADGISQVANFMDTAVFGMFELPLTRQAPSQGNAAEKGEQPIAGTRAR
>NZ_CP016353.1|WP_091803086.1|6216249_6216678_+|hypothetical-protein
MLRHRFVLAVVAIVVVWLAVVTVQIARQPEIGVDSPQQLQRQLATALNARDAGALAEVVGYPVAEVDDFAKAYLARLDEVNASAITVTLLPDPRDPKAAEIRGERASTRPAAGNQGSRVTFSYRVAVGQVDGSWRVEFIPPL
>NZ_CP016353.1|WP_091803088.1|6215123_6215996_+|PaaX-family-transcriptional-regulator
MHADDEADPAGATWQRPQALLLNFFAAHFLGRTEAVYSGSLIDVLARVGVGEHAARSTFSRMTRRGLLERHREGKRVYLSLTEHTVNVLEEGAERVKQAVNRSWDGHWTVLGFSLPETRRSDRHLLRSRLAWAGFGPLQNGLWITPRPIDVDRLLDGLDVAENVKAFRATTLHPTDIHEMISETWDLAELSAGYREFLARWDSVDTIPSDEDILARQLRMHTEWTLLLRTDPGLPLEHLPSDWPAVRAEHVFLRMRSLFAPPANREVSGIVDRLPLPRPEPDNRSGHRSA
>NZ_CP016353.1|WP_091803091.1|6214503_6214824_+|STAS-domain-containing-protein
MTTAHVEIRDHAAERVDLAISGEIDLSNSAVVRDRLFASISNRVTAVRIDLSGLDYIDSAGLRILFALADRLRLLQTSCELMVPPGSPTQKVIQLSGLDTLVTLTT
>NZ_CP016353.1|WP_091803094.1|6212707_6214507_+|SpoIIE-family-protein-phosphatase
MPKSVDSDDAEDRLRRIEAITDTTLGELDVEELLHQLLERVRSILRADTATVLLLDRDGRHLVATASSGIEEEVRQGFRIGVGEGFAGKIAATRQALTIDQVDSTTVINPLLWRKGIRSLAGVPLITGGELLGVLHVGAVKRVGFTDQDLHLLRLAADRVALSTHAKLTRVEKAAASALQRSLLPARLPDVPGLELAARYAPGDGGDISGDWYDVFTLPSGWLCVAIGDVVGRGLAAATVMSRLRTATRAYALESRDPSEVLTKLDRHIRTFEPDTMATIAYAMWEPTLRRMHISLAGHLSPVVAPPQGPPAPADVPVDPPVGYGSGALRRRTTIIDVPLETLVLFYTDGLVERRNRSLSEGLALLADCFSGETADELCSAVLAGLLGSERNEDDVAVLAIRARELPVLDFEIDAVPQSLAEVRAALRRWLPSAGADENEVGELLVVVGEACANAIEHAYGPVGGTVRIRLERRAPDVLVTVSDEGTWREPRGRNRGKGTELMRKLADDLRFEHTAKGTTAHIRRRLAARAEESGGPSGALPRTGSGVSASGVASQDAAPPEVTSSEPLSDATGEHGRKTLPITGSDHSPTTPESEALS
>NZ_CP016353.1|WP_091803875.1|6211882_6212611_-|dienelactone-hydrolase-family-protein
MIIDVVATRYENIEAFDGGNFDAYWAVPDSTPGAGIVLLQEVFGINDNMRQLAAELAGHGYVTVVPDMFWRLQRGFESKDESGIQEGMGLAQRLDFTAAVADMTATMRALRAMPECDGRVGAAGFCLGGTLAYLFATSVRDEGRGPDAVVSYYGSAVHAMLEKVGDIDCPMLFHYGDADPYISTEQIAAVEAAVAGRPDIAVHHYDAGHAFSNFDAPSFYQRDAADLAWGRTLAFFDDRLSG
>NZ_CP016353.1|WP_091803072.1|6223160_6224678_+|threonine/serine-exporter-family-protein
MKLRPRARTAPNRRHAWQILEAPAEDQSDKHGRRQPQSRKSSRRAWHILEAPTGELPVVDTTATMGPQLPDEATVHLVLDLVLRIGEVQMASGAGASDVTATILALTRALGLPHCEVDVIFTSITVSCHRGSELSPVTAVRVVRSRSLDYTRLSDTERLVQKLLRNRISTEDAYTELHQITNAKHPYPRWVSTLAWGGMAGFITLLLGGTGWAPFISFVISAVVDRVGRRLNRLQLPFFFQQVAGGFVATLAAIGIVNLDFFPLQPTLVVAAALTVLLSGLSTVSAVQDAITGYYVTAAGRTLEVVLMSAGLITGVAFAISIANQLGAPIAPPPTAAVPDVTAVGVLITLVAGCGAAACFALASYSKLRPLLVAAIAGGVGAGSYGLLLATGASPIIASAVAATLVGFGGGVLSRRLQVTPLVVAVSGITPLLPGLATYRGLSDLADGGSMGTLMGAIAIGLALAAGVVLGEFLAQPVRTGLGRLERKLSGPRLAGPLDTGQRLE
>NZ_CP016353.1|WP_091803069.1|6224702_6226154_+|trehalose-6-phosphate-synthase
MPSEGNAEPSEARAEFVVVANRLPVDLDRAADGTQRWTQSPGGLVSALEPFLRSRKGAWVGWPGVPDVEVDEFTDEGLILHPVSLSSADVRDYYEGFSNATLWPLYHDVVAPPIFDRSWWESYVRVNRRFAEASAAVADEGATVWVQDYQLQLVPSMLRELRPDLRIGFFLHIPFPPVELFMQLPWRAEIVRGLIGADLVGFHRPGGAQNFLWLARQLIGLEPSRGSVGVRSRPGMVQVGDRTVRVGAFPISIDAAGLDALSRTKAVSERAAQVRSDLGNPKTILLGVDRLDYTKGIDLRLQAFHELLQEGRVNPEDVTFVQLATPSRERVEHYQRMRGEIEQMVGRINGEFAKVGHPVVHYLHQSVNRKELAAFFSAADIMVVTPLRDGMNLVCKEYVACRHDLGGALVLSEFAGAAAELSSAFLVNPHDLDGVKNALEQAITLDPAEGRRRMRALRRQVLTHDVDRWARSFLEALGSEPAA
>NZ_CP016353.1|WP_091803869.1|6226190_6228719_+|trehalose-phosphatase
MTAEALPAELRRAIVQIARTPRLLVACDYDGTLAPITENPDEARARSESVGALRSLAGLHETTTAVISGRALRDLATLSRLPAEVHLVGSHGSEFDIGFVHEIDAEAKDLHRRVEEELDRLIDGVRGASLEVKPASIAVHVRRAERAEAKRIIESVHSGPSRWEGVSTTDGKEVVELSVIQTDKGNALDTLRHQAGATAAVFVGDDVTDEKAFVRLTGPDLGIKVGDGDSAAQYRVGDTEEVATVLAFMLEERRNWLYGEQSPPIERISMLASERAVALLTPDAKLTWLCHPGPDAAAVFADLLGSESAGHFSIKPDRNGLPLGQRYLPNTMTVETRWSRLLVTDYLEPECATHRTDLVRVISGEATASIVFAPRPEFGGVPVSLIQEQDGLRVLGTSEPFVLRAPGVQWEITNDGMHDTAKALVQPTATQPVVLELRCGTTDLGPHQLSEIDRRGRAGEYWSEWATTLKLPNVEPELVARSALTLRGLANSDTGGVMAAATTSLPEEIGGVRNWDYRYCWIRDGAMTVRELVSLGSLDEAEGFLRWLHGVLATLAGPERLHPLYTLAGTQLGAEAVIDSLPGYKGSRPVRVGNLANHQVQLDVFGPVVELVMTLAEARGNLRDQDWQLVRAMAEAVKRRWDEPDHGIWEERHVPRHRVYSRVMCWVTLDRAIKLGEIYGRPVPEGWAQLRDTIAHDVLEHGWNDEVRAYTTAYDGVDLDAASLFVGLSGLLDPADERFQSTVTAIEAELRSGSTVYRYRRDDGLPGDEGGFHLCAAWMIEAYLLTGRRTEAQELFQQLVDAAGPTGLLPEQYDPVAERSLGNHPQAYSHLGLIRCARLLAE
>NZ_CP016353.1|WP_091803066.1|6228722_6230096_-|DNA-repair-protein-RadA
MVKKASSSFRCAECGLEVAKWVGRCPECQAWGTIEERGESRPPIARVAAGAPSAPARPIAHVDIESSRAAETGVSELDRVLGGGLVPGAVVLLAGEPGVGKSTLLLEVAHRWAERAKAAPALYVTGEESAGQVRLRAERTGNVHERMYLAAESDLGAILGHVDDVKPGLLIVDSVQTMSSPQVDNAPGGVTQVRAVTAGLVALAKERGLPIVLVGHVTKDGSVAGPRVLEHLVDVVLHFEGDRHSTLRLVRGVKNRFGAADEIGCFELRDDGIVGVPDPSGLFLNRHAEAVPGTSVTVTVEGKRPLLGEVQALVGRSTLNQPRRAVSGLDSSRVSMVLAVLEKRGRIQLGDKDIYTATVGGMKVTEPAVDLAVALAVSSAFTDTALSPRLVAIGEVGLAGEVRRITGVGRRLAEAVRLGFTHALVPPDAGPMPEGIQALEVGDLAGALHAVKYVPVG
>NZ_CP016353.1|WP_091803063.1|6230125_6230659_-|copper-chaperone-PCu(A)C
MLGAAAFGLGAALLVTGCGAGQITQTDTQVAAVNGAEAQVGTMAIRNAELAYPSGGEPAVHTEGSNADVLMSIVNQSLEEDQLVSASSENADSVELGGERAIPGNTTLAIGPTAPGGEQQLHGTITLQGLKQEVRPGQNLVITLTFREAGEVQVDLPVMAPTEPRASEEEHEEGGGH
>NZ_CP016353.1|WP_009156479.1|6230992_6231484_+|CarD-family-transcriptional-regulator
MVFKVGETVVYPHHGAALIEAIETRVIKGEEKQYLVLKVAQGDLTVRVPADNAEIVGVRDVVGQDGLNRVFDVLRAPHTDEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRREKDRGLSAGEKRMLAKARQILVSELALAEGTDEGKAEVLLDEVLETAAV
>NZ_CP016353.1|WP_091803061.1|6231498_6232137_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MALVPLGNRDRHHSGALTRFRGEPLLSHAVRGLLRSGCVDRVVVAGPPHNVAAYSAALALVNDAEVKVLAGGGDRIESMRSALTASSPEPTDLVLVHDASRPFTPTATFTAVVSELKAGAVAAVPVEPVTDTIKIVDSDDVIRGTRDRTLLRSIQAPQGFRAATLRGTNTGDPLTELGAKVRTVAGHPHGMRLVSAFDLAVIEALLAAEGTP
>NZ_CP016353.1|WP_091803058.1|6232133_6232607_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGQGIDVHPIETGKECWIAGLHWPGISGCAGHSDGDVASHALCDAVLSAAGLGDLGAVFGTGQPRWAGAHGAELLAEVRRLVEEQGLVIGNATVQVIGNAPRIGTRRAEAQRVLGDALGCPVSVAGTTTDGLGLTGRGEGLAAIASALLMSKNTG
>NZ_CP016353.1|WP_091803055.1|6232617_6233304_+|HAD-IA-family-hydrolase
MTIQAVMFDFSGTLFRLEQDESWIDELTGADGDPLDVEAQAELMRRMTAPVTQILEFTDEYQHAWDNRDLDPELHSKIYLEVLRQSGIPQPEQAKALYDRLIDPSEWTPYPDAEAALKELADRGVRVGVLSNIAFDIRPAFREHGLDAYVDEFVLSFEVGAIKPDPAIFRLLLDRLGIAAENALMVGDSAEADGGAKELGSAFALVEPLPTGEREEGLLTALREHSVL
>NZ_CP016353.1|WP_091803052.1|6233320_6234703_+|cysteine--tRNA-ligase
MVLHLYDTATRSVREFHPARSGTASMYVCGATVQGVPHIGHVRGALNYDVLRRWLLHNGLDVLMVRNVTDIDDKILTKAADADRPWWEWAATHERAFEDAYQALGCLPPSIAPRATGHVTQMVELIQRLIDRGHAYPADGDVYFSVTSFAGYGALSGQRLDEVQQGETQAEGKRDPRDFTLWKGSKPGEPSWPTPWGRGRPGWHLECSAMSTTYLGAEFDIHGGGVDLVFPHHENERAQSEAAGDPFARFWLHNAWVTLSGEKMSKSLGNVVSIPEMLRRYRAVELRYYLIQPHYRSTIEYSDEALTESAQGFRRIEQFLRRAAGSAGEVRIGKVPAEFATALDDDLGTPQAFAVLHNTVRDGNAALDAADSAKAVELAETVRAMTSVLGVDPLSTAWADTEESSGTDALGSLVEAMLAMRQQARADKDFAKADAIRDQLTHAGIAVEDTPNGPMWTVRD

Crispr_ID: NZ_CP016353_12

• CRISPR_ID: NZ_CP016353_12
• CRISPR_location: 6488116-6488426
• CRISPR_type: Orphan
• Repeat_type: I-E
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP016353_12

Consensus_repeat	Method
GTGCTCCCCGCGCACGCGGGGATGGTCCG	CRISPRCasFinder

spacers of NZ_CP016353_12

>12.1|6488145|33|NZ_CP016353|CRISPRCasFinder
CGGAGTGCTACTACCGAGCACTCGACGGCAGTG
>12.2|6488207|32|NZ_CP016353|CRISPRCasFinder
CGCAGCAACACGGCGAATCCGTCGTCGGTGGT
>12.3|6488268|32|NZ_CP016353|CRISPRCasFinder
CCCCGGCGACCTCTTCAGCTCCGTACGAATAG
>12.4|6488329|69|NZ_CP016353|CRISPRCasFinder
TCCTCGGGGTGCTCCCCGCGCACGCGGGGATGGTCCGTCGTCCGTCGAGCCATGTGGCAACTTCAGAGC

CRISPR arrays and Neighbor proteins around NZ_CP016353_12

CRISPR arrays

The CRISPR arrays of NZ_CP016353_12

>merge|NZ_CP016353|12|6488116-6488426|CRISPRCasFinder
GTGCTCCCCGCGCACGCGGGGATGGTCCGCGGAGTGCTACTACCGAGCACTCGACGGCAGTGGTGCTCCCCGCGCACGCGGGGATGGTCCGCGCAGCAACACGGCGAATCCGTCGTCGGTGGTGTGCTCCCCGCGCACGCGGGGATGGTCCGCCCCGGCGACCTCTTCAGCTCCGTACGAATAGGTGCTCCCCGCGCACGCGGGGATGGTCCGTCCTCGGGGTGCTCCCCGCGCACGCGGGGATGGTCCGTCGTCCGTCGAGCCATGTGGCAACTTCAGAGCGTGCTCCCCGCGCATGCGGGGCCCTCGTG

>NZ_CP016353|12|11|6488116-6488426|CRISPRCasFinder
GTGCTCCCCGCGCACGCGGGGATGGTCCG	CGGAGTGCTACTACCGAGCACTCGACGGCAGTG
GTGCTCCCCGCGCACGCGGGGATGGTCCG	CGCAGCAACACGGCGAATCCGTCGTCGGTGGT
GTGCTCCCCGCGCACGCGGGGATGGTCCG	CCCCGGCGACCTCTTCAGCTCCGTACGAATAG
GTGCTCCCCGCGCACGCGGGGATGGTCCG	TCCTCGGGGTGCTCCCCGCGCACGCGGGGATGGTCCGTCGTCCGTCGAGCCATGTGGCAACTTCAGAGC
GTGCTCCCCGCGCATGCGGGGCCCTCGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016353.1|WP_091805481.1|6481380_6482952_-|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NZ_CP016353.1|WP_091805502.1|6494018_6494594_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_CP016353.1|WP_091806506.1|6492614_6494009_+|MFS-transporter	unknown	unknown	gnl|CDD|340924
NZ_CP016353.1|WP_091805484.1|6483132_6484140_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380516
NZ_CP016353.1|WP_091805530.1|6499176_6500577_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091805494.1|6485813_6486359_-|flavin-reductase	unknown	unknown	gnl|CDD|376575
NZ_CP016353.1|WP_009156738.1|6490622_6490826_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP016353.1|WP_091805489.1|6484356_6484554_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_185769991.1|6491249_6492464_+|L,D-transpeptidase-family-protein	unknown	unknown	gnl|CDD|380079
NZ_CP016353.1|WP_091805499.1|6489266_6489515_-|hypothetical-protein	unknown	unknown	gnl|CDD|236422
NZ_CP016353.1|WP_091805497.1|6487254_6488007_+|S1-family-peptidase	unknown	unknown	gnl|CDD|365866
NZ_CP016353.1|WP_091805487.1|6484099_6484345_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091805525.1|6495769_6498199_-|protein-kinase	unknown	unknown	gnl|CDD|319004
NZ_CP016353.1|WP_091806497.1|6486479_6487172_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|224332
NZ_CP016353.1|WP_091805478.1|6480382_6481384_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224093
NZ_CP016353.1|WP_091805476.1|6479337_6480390_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224093
NZ_CP016353.1|WP_091805492.1|6484526_6485753_-|monooxygenase	unknown	unknown	gnl|CDD|380046
NZ_CP016353.1|WP_091806500.1|6490014_6490461_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP016353.1|WP_091805528.1|6498217_6499177_-|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_CP016353.1|WP_091805522.1|6494593_6495769_+|metallophosphoesterase	unknown	unknown	gnl|CDD|277331

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP016353.1|WP_091805481.1|6481380_6482952_-|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP016353.1|WP_091805502.1|6494018_6494594_+|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.95935e-12
NZ_CP016353.1|WP_091806506.1|6492614_6494009_+|MFS-transporter	gnl|CDD|340924	cd17366, MFS_ProP, Proline/betaine transporter of the Major Facilitator Superfamily of transporters. This subfamily is composed of Escherichia coli proline/betaine transporter, also called proline porter II (PPII), and similar proteins. ProP is a proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. The ProP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.79499e-145
NZ_CP016353.1|WP_091805484.1|6483132_6484140_+|substrate-binding-domain-containing-protein	gnl|CDD|380516	cd06293, PBP1_LacI-like, ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.12913e-107
NZ_CP016353.1|WP_091805494.1|6485813_6486359_-|flavin-reductase	gnl|CDD|376575	pfam01613, Flavin_Reduct, Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. VlmR is a flavin reductase that functions in a two-component enzyme system to provide isobutylamine N-hydroxylase with reduced flavin and may be involved in the synthesis of valanimycin. SnaC is a flavin reductase that provides reduced flavin for the oxidation of pristinamycin IIB to pristinamycin IIA as catalyzed by SnaA, SnaB heterodimer. This flavin reductase region characterized by enzymes of the family is present in the C-terminus of potential FMN proteins from Synechocystis sp. suggesting it is a flavin reductase domain.	5.84625e-41
NZ_CP016353.1|WP_009156738.1|6490622_6490826_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.90624e-34
NZ_CP016353.1|WP_091805525.1|6495769_6498199_-|protein-kinase	gnl|CDD|319004	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat. This domain is found at the C-terminus of protein kinase G and contains a tetratricopeptide repeat (TPR).	5.45472e-91
NZ_CP016353.1|WP_091805522.1|6494593_6495769_+|metallophosphoesterase	gnl|CDD|277331	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain. YkuE is an uncharacterized Bacillus subtilis protein with a C-terminal metallophosphatase domain and an N-terminal twin-arginine (RR) motif. An RR-signal peptide derived from the Bacillus subtilis YkuE protein can direct Tat-dependent secretion of agarase in Streptomyces lividans. This is an indication that YkuE is transported by the Bacillus subtilis Tat (Twin-arginine translocation) pathway machinery. YkuE belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.12681e-70
NZ_CP016353.1|WP_091805499.1|6489266_6489515_-|hypothetical-protein	gnl|CDD|236422	PRK09234, fbiC, FO synthase; Reviewed.	0.00124937
NZ_CP016353.1|WP_091805497.1|6487254_6488007_+|S1-family-peptidase	gnl|CDD|365866	pfam00089, Trypsin, Trypsin.	2.43641e-17
NZ_CP016353.1|WP_091806497.1|6486479_6487172_+|helix-turn-helix-domain-containing-protein	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	5.06069e-28
NZ_CP016353.1|WP_091805478.1|6480382_6481384_-|ABC-transporter-permease	gnl|CDD|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.63238e-74
NZ_CP016353.1|WP_091805476.1|6479337_6480390_-|ABC-transporter-permease	gnl|CDD|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.23386e-67
NZ_CP016353.1|WP_091805492.1|6484526_6485753_-|monooxygenase	gnl|CDD|380046	pfam17885, Smoa_sbd, Styrene monooxygenase A putative substrate binding domain. This domain is found in the 46 kDa FAD-specific styrene epoxidase (SMOA) protein, comprises a part of the styrene monooxygenase (SMO) two-component flavoprotein monooxygenase enzyme. Structural analysis indicates that SMOA monomer comprises two globular domains spanned by a long alpha-helix. This domain contains a putative substrate binding site.	9.8844e-38
NZ_CP016353.1|WP_185769991.1|6491249_6492464_+|L,D-transpeptidase-family-protein	gnl|CDD|380079	pfam17964, Big_10, Bacterial Ig domain. This entry represents a bacterial Ig-like domain found associated with transpeptidase domains.	8.16981e-84
NZ_CP016353.1|WP_091805528.1|6498217_6499177_-|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.54371e-100

Protein sequences

>NZ_CP016353.1|WP_091805497.1|6487254_6488007_+|S1-family-peptidase
MTALAGLTAFSLLQATPANAIANGDDVADGEYSFSVSLSMPEITRGDGSTYASACSAALISDQWIITAGHCFHDGDGNRVDGEPRYQVAATAGQATLSGDDGITVDVVEVVQSEEVDVAIAKLAEPVADIEPLKISESAPAEGDVVRLVGWGSSDATADLSHRPDRMQTGQFTVTGSDDQIVNFTGYLPKRDVSACPYDSGAPFFAESEDGTYELVATEIGGPDCPHAEEEIAARSDVLHDWIKEHVRLP
>NZ_CP016353.1|WP_091806497.1|6486479_6487172_+|helix-turn-helix-domain-containing-protein
MPAKPGVRAQTLDRALDVLEILADGQPRSSQELAVASDLHRSIVYRILRTLEDRDLVWRNAEGRYTLGLGLLVLSRTVLGDAQARMQDVLGELANSVSATAFFSVPQGSEVVALVTVEPSRHRAAIAYRPGARSPLDRGACGLAILASSPARQGERREVGVARRLGFARTVGEVHAGLTEIAAPVRLSHGTAGAVGIVFVAGDVAEDEAAVTVRGTAARLSAPAAEVWEM
>NZ_CP016353.1|WP_091805494.1|6485813_6486359_-|flavin-reductase
MRTPAEVSVTRTSSLSSRPAIDPAHFRRTMGRFTSGVTVITTVDEGRVHGMTANAFLSVSIDPPLVLISLAKESRMAALLPTTGRYGVNVLAEHQRTHSQHFAGRPVPGLAPEFQFTDEHAFLPGSMAQIGCDLVSTHEAGDHVLHIGHVTHLAHSDGEPLVFFTGAYRALYSDGDDNRAS
>NZ_CP016353.1|WP_091805492.1|6484526_6485753_-|monooxygenase
MDGIGIIGSGIAGLQLGLQLRQHDIPVTIYSDRPADDFGKGRLPNTVAHHHTTVARERELGIDHWDIDEYGYFGHHHYIGGETPLRFFGEFAAPSRALDYRVYLPRLLRDFDERGGDFEVRPVEPADVTALSEQHDLVVVSSGRTGLGGMFPRRADKSPFDTPQRKLCAALYEGIAYSEPKGVTMSIAPGHGELLEIPMFSVAGHVTALLFEIVPGGDLEPIGEARYDEDPGGFEKLVLAKLRQHHPTTFERVDHGRFRVTGPQDLLQGGLVPGVREDYVRLANGRYVIALGDAHTVVDPIVGQGANCASYSAWELGQAIVTDPNFDERFCRKVAQRRENRVHATSDWTNLMVRFPPAPHLLQLLGSMARNQVVADEFTDNFSYPERQWDILATPERTRSYLARHGMA
>NZ_CP016353.1|WP_091805489.1|6484356_6484554_+|hypothetical-protein
MELDAPNADLDRTHADLDVLSAELATPSAGLDAPNAELDRTSAGLAHPSAGLAHRSCQAIPWRAR
>NZ_CP016353.1|WP_091805487.1|6484099_6484345_-|hypothetical-protein
MLGYRMRLGDLVANGHLAVRTMSGLAAPDADLVCASADLDDLDADVDVLSADVGDASAELGCGCGAAFVSRLSTRGPPAPA
>NZ_CP016353.1|WP_091805484.1|6483132_6484140_+|substrate-binding-domain-containing-protein
MSPSIKDVAERAGVSVGTVSNVLNHPERVSTNTRESVLTAISALGFVRNSSAAQLRAGTSRSIGLIVLDLANPFFHDVARGVEQVADELGYAVVLCNSDDQTERENRYLQVLEEQRVRGVLITPVEVSSGRLDALRKRGTPTVLVDRHDPRINCCSVAVDDVGGGELAGAHLLSLGHQRIRYFSGPLTLRQCADRLAGLRKAVTEAGLDPERAIEVVEERAMNARTAYGAAKKRFGNRDKATAAFCANDLMALGVLRAAVSEGRQVPGELAIVGYDDIEFAADAAVPLTSIRQPTQHIGRAAAQLLVEECDNPDTHAHQQVMFKPELVVRESTTG
>NZ_CP016353.1|WP_091805481.1|6481380_6482952_-|sugar-ABC-transporter-ATP-binding-protein
MKRFTISIEGGIVGAPEHPPAPLLELKDVTKSFQAVRALRGVSLALRPGEIHALAGENGAGKSTVVRVIGGEHQPDSGELLLEGSPVRFASPREAQHRGVAVIHQEPIQFPDLSVAENVFMGRQPLRRGRRIDRRAMHRRSAEVFEQLGVPIAPSRQTRGLSIADQQIIEIAKALVADARIIVMDEPTAALSAVEAQRLFRVARGLAEQGAALLFISHRLDEMFALCDRVTVLRDGAFVTTAPMSEIDNDTLVRRMVGRSVEQLFPKRETDIGAEVLVVEGLTRAGDFADVSLTVREGEIVGLAGLVGSGRSEVARAVFGVDDRDAGTVTVNGKPLPAGKPGSAIEKGVALVPEDRREQGLVLELSIERNASLARLKQVSPGGITRSSRERALAQTWAERLSLKFGSLADPAATLSGGNQQKIVLGKWLATEPAVLIVDEPTRGIDIGAKVEVHGLLSDLAARGIGILLISSELPEVLGMADRVLVMHEGRITAELAREEATEEAVMYAATGNGASATKGSAA
>NZ_CP016353.1|WP_091805478.1|6480382_6481384_-|ABC-transporter-permease
MNRIRALLSGRELSIVLALFAVVVVTTVVNPAFLNAQGIHDLFLNASIIALLAIGQTLLVITRNIDLSVGSVMGLTAYMSGQMFIADHETPTIVVVLAGMALGAACGAFNGALVAIAKVPALVVTLGTLYVFRGIDYGWASATGVHQINADQMSSGFLSFGSGSILGVPHLTLIALAALAIAAYALHNWRSGRELYAIGSNPQAARLAGIPAGRRVFTAFVISGALVGLAGVLHASYFGTINASVGTNRELAVVAAVVVGGVAIFGGSGTVLGAVLGALLLTTITSALPILGVPAFWQRAVDGAALLLAISLDRAVMVRMAERLRKERSLRRA
>NZ_CP016353.1|WP_091805476.1|6479337_6480390_-|ABC-transporter-permease
MRERLLRWETILLVLCVVVFTWGSATTAGFGEADNISFLLLDYTEVALLALALLPIILTGQIDLSVASILGFCSALTGVLWDAGMSFETIVPIVVVAGAVLGSLNATLIVRFGLPALAVTIGTLGLYRGLAYVLLGDRAVTGFPDAYRPLVTDTVPGTFLPYATVLVIIVGVLAAVVVHYTPFGRSLYAIGLGEQTARFSGIRVQRVRFVLYIVSGALCAVASLVYTLRYNSARADNAAGLELVAVAAVLLGGVSIFGGRGAVVGVVSALLLMAGLRNVLFLNDITNEIQNVINGLLLIISVLVPVIANLLRGKRHPMPAEQRGQPPPEETPQDPVAATAVHGSPEEDQR
>NZ_CP016353.1|WP_091805499.1|6489266_6489515_-|hypothetical-protein
MSGSVEVRQFLLRYEGEGQAAGYGGVPAQRSGQADASRVSDDQVRRARLAVARGATSVEDCAQLLDMLGLKPDPDGKSPVQG
>NZ_CP016353.1|WP_091806500.1|6490014_6490461_+|hypothetical-protein
MPLPAFGRLGSRTNLKPANSGRHRGAVDNAADPAAEDHELTSYLAALAPESDPESTGSGRRFGDAQVYQLRVNLIASQQLKELAAFRGTSPQALAQEWVLERLAWESQIESEERAQRHAEPRATGEPQTDQYFFDQQQWEQSARGPLR
>NZ_CP016353.1|WP_009156738.1|6490622_6490826_-|cold-shock-protein
MAQGTVKWFNAEKGFGFIAQDGGEGDVFVHYSEIEGRGFRTLEENQRVEFEVGQGQKGPQAQKVRAL
>NZ_CP016353.1|WP_185769991.1|6491249_6492464_+|L,D-transpeptidase-family-protein
MDGEKGTHVSQRKGARRGNTRGSTALMLAILLGLAACTGDGGNGDGNSGSEDSKPAAKITAQPEDGKKDVAPRDPIRLSVAEGTIKSVALTNPEGTPVDGEVAKDQRSWTATEPLGYAKTYTWSGTAVDKNGKETPINGSFSTVAPKATAGGRLNVGDDGIYGIAMPISLTFDAPVTDKVAVEKALHVETTPQTEGSWAWLENDTSVHWRPKDYWQPGTTVSVRADIYGVHIGDGTYGEADVTSNFSIGRSQIVKGNTQTHRMVVIRDGQQIADYPVSYGLDSDPGRVTHSGTHVVMSKHPVYYMTNPGYGYRDFEVNWAVRISNNGEFTHAAPWSVGDQGYTNVSHGCINMSVADAKEYYDGVLPGDPVEIEGSTQQLGPEDGDYHDWTYSWADWSALSALTQ
>NZ_CP016353.1|WP_091806506.1|6492614_6494009_+|MFS-transporter
MAEDAAGAAERAPYVPSNTDVRKAVAGSAMGNCIEWYDFGVFGFMPAILGQVFFNAGSTAEGALATFALLAVTFVIRPFGSFILGPLGDKLGRQKVLAMTIILMSGSTFAIGLLPTFNEIGMVAAVLVIGLRALQGFSAGGEYGGAATFLAEYAPDKKRGFLGSWLEFGTLTGFFLGASTVTVTTMLVGDAAMHSWGWRIPFLIAGPLGLVGFYLRNKLEDTPVFQEIEQQHKVAKSPLKELITKHWKSILHLIGLVIMLNVGDWIMLAYVETYLKDVLGMTGNTPLLIVMGVILAMLVLIVPLGALSDRIGRKPILMASCAGFLILPIPAFTLMENSKTASGVNVLMLAGGLAMIGLCLVLFLSIVASTLPAMFPTQVRYGAFSIGYNVSTAAFAGTAPYIVGSLVDATGNTLWPAFYLMGAAAIATIPVLLLPETNGVALRDIVSSRMFVGKTGPSASPATG
>NZ_CP016353.1|WP_091805502.1|6494018_6494594_+|PaaI-family-thioesterase
MSNPPSWPPVPTEPVVPHPAAPEPGSKLGIHFDQCFGCGDDVEGGLHIRSSVAEDLVVESQFAVTKAHQGAPGLAHGGLLVCAFDEALGSAVGNLLRRPAVTGKLETDFRRPVPVGSTLFITTRFDGIAGRKVFVSAEGRLDAADGPVAVQARALFVTVGIDHFTTHGDVDALEKLRDSRGADAKDWDINP
>NZ_CP016353.1|WP_091805522.1|6494593_6495769_+|metallophosphoesterase
MFILLAIALIAIVHLYVWKRLVFDTTSPKSRARKVGTAAIVALVLLMGVALGTGTSIDPAIARWFAWPGYLWLAMFFYLLVVLVVLEIPRLALRGWVRKGDKPAEPESTADERGGVTRRVALARGSAAVAGVVATGFVGYGMTVALGPPTVTRVPISLPRLDPRASGCRIALISDVHLGPIIGRSFTERIVELVNAERPDLVAIAGDLVDGEVRHLAHAAEPLADLRSTHGTFYVTGNHEYFSGYREWIEHVPSLGIRPLRNEHVDIEHNGGVFHFAGINDHIGYQWQDPGDVARAVEGRDPDKALVMLAHQPVDITPAVEHGVDLMLAGHTHGGQLSPFELIVSLQQGAVAGSYQFDDTKMYVTRGAGFWGPPVRVGAPPDITIVELRPS
>NZ_CP016353.1|WP_091805525.1|6495769_6498199_-|protein-kinase
MSDEQHRPGHVIPDEAEHVPRVTPDTQVIRPVSVENQEPQPTSVLAAPAPETESIAPPDPPKEPSGPGPLPDPGTESVLPPSTSGGIRPGTGPGTGPGTGSGAFPGTSRRSSRRTARRGRLGAGIVEVPPVPYRDPAAAVLHNPMVSEEKRYCGNCGIKVGRSSEGEPGSPEGNCPDCGTWFSFVPRLRPQEIVGGQYEVLGALAYGGLGWIYLAQDHNVSDRWVVLKGLIDTGDATAMAAAVNETRFLAEVEHPNIVKIYNFVQHPDPDTGNSVGYIVMEYVGGDSLRELALAHHRASGRAEPLPIGQVIAYGLEILPAIGYLHGQGLLYCDLKPDNVIQTHEQLKLIDLGAVRRMDDYTSPLFFTTGYSAPELATRGASVASDLFTVGRTLAVLSFEFSGYTTKYKTTLPGQEDVPLFRLFGSYYRFLRRATHADPDRRFIAAEDMADQLTGVLREIMAMGTGKQRPAASTVFGPEIDAFGVDMVVPDPGKGVSLPDPAEVVMGLPIPQVHTDDAGAGVLAAMTAADPKTAIEALAKAPRESIEVRLRIVRARIELGELAEANRQLQAAQYLAIKAGFPHDWRIDWYRGLIELAGGRSKVAHVAFDAVYDELPGEVAPKLALAFSAESVGDFFNASRLYELVWRTDRTYVSAAFGLARVYLAQGARAGAIEVLESVPASSTHHVAAQVAAIKIKTRVNGGEAAHTVGERDLVDAANRLQRLSLDAERRAMLSAEVLESAFEWIRSPAGQRYASVGDGAQVLGRRLDERELRFGLEDCYRTLAKLADTAEQRIELVDKANAVRPRTRT
>NZ_CP016353.1|WP_091805528.1|6498217_6499177_-|glutamate-ABC-transporter-substrate-binding-protein
MNRKTRWTVLLAATAALVAGCGSPGAPVDPAPVESVQRPMPPNAAEEHDVDGGGSTNDGCNPAASLGPSGNVPSGSTMDEIRQRGYLIVGVDQNTFLFGFRNPTTGKLEGFDIDIAKQVAKELLGDPEAVQFKAISSAQRIPTLTEGQVDIVVRTFSITCERLEDINFSTVYYVAGQRVLVNKDSDVEGVGDLGGKRVCASKTSTSLPNVVQAAPEALPISVDDWSDCLVMLQQGQVEAVSTDDTILAGMAEQDPTTKIVGDRFTDELYGIGIPKENTDMVRYVNYVLDKVRGGPWQDSYRTWLLDRLGSASPPRPEYQ
>NZ_CP016353.1|WP_091805530.1|6499176_6500577_-|hypothetical-protein
MTSTVTGRGPSVPPTRPRREPRPTRSGVGWLLELPANAVRRVARSAKATPGRLSLIATGLIVLALVTGLVGTASVLNRDNTINALIDHREPLAAAAQEVYGSLSDADATAASAFLSTGTEPPELRERYELDIARAGAALAKAASDSGSVPEAAEQVGILSQRLPVYTGLIETARANNRQGFPSGAAYLREASELMRSQLLPAAHRLYEIDAQRLVDEQDTASGVPWLTAVLVFGLLAALIATQIHLKRRTNRVFNIGLLVASIAVGLSILWGAGALTVQSVLVSSGRSTGTEQADLLVRARIAALQARADETLTLVARGGGESYDKEFGELFGQFAGEDGQGGLLGEARRGAEGGPETTHIASAANHATTWLRAHGEVRRLDDSGNYAEAVGLAIDGTDEEGAAAAFSRVDGDLVAAIGVARQSFLDETTNGSRALTLLAPGFAVLAAIAALGTTLGFRERLREYR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016353_7	7.2|3008316|25|NZ_CP016353|CRISPRCasFinder	3008316-3008340	25	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	8646-8670	3	0.88
NZ_CP016353_7	7.2|3008316|25|NZ_CP016353|CRISPRCasFinder	3008316-3008340	25	NZ_CP012917	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence	643819-643843	3	0.88
NZ_CP016353_7	7.2|3008316|25|NZ_CP016353|CRISPRCasFinder	3008316-3008340	25	NZ_CP032343	Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence	84770-84794	3	0.88
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	MH271312	Microbacterium phage RobsFeet, complete genome	19965-19997	5	0.848
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	NC_047988	Microbacterium phage Metamorphoo, complete genome	19684-19716	5	0.848
NZ_CP016353_5	5.11|2186031|32|NZ_CP016353|CRISPRCasFinder	2186031-2186062	32	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	538709-538740	6	0.812
NZ_CP016353_6	6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT	2666042-2666074	33	MN234170	Mycobacterium phage MalagasyRose, complete genome	2809-2841	6	0.818
NZ_CP016353_6	6.8|2666164|33|NZ_CP016353|CRISPRCasFinder,CRT	2666164-2666196	33	AP014065	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C13-MedDCM-OCT-S36-C38, *** SEQUENCING IN PROGRESS ***	17605-17637	6	0.818
NZ_CP016353_9	9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT	4403470-4403502	33	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1948647-1948679	6	0.818
NZ_CP016353_9	9.5|4403714|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT	4403714-4403746	33	AP017924	Ralstonia phage RP12 DNA, complete genome	178716-178748	6	0.818
NZ_CP016353_9	9.5|4403714|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT	4403714-4403746	33	AP017925	Ralstonia phage RP31 DNA, complete genome	175462-175494	6	0.818
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	NZ_CP053567	Pseudonocardia sp. Gen01 plasmid unnamed3, complete sequence	14488-14520	7	0.788
NZ_CP016353_4	4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT	2175278-2175310	33	NZ_KM017071	Sphingomonas sp. JE1 plasmid pJE1, complete sequence	23675-23707	7	0.788
NZ_CP016353_4	4.10|2175705|34|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175705-2175738	34	NZ_LN832560	Paracoccus aminovorans isolate JCM7685 plasmid II, complete sequence	185137-185170	7	0.794
NZ_CP016353_4	4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175828-2175860	33	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	212488-212520	7	0.788
NZ_CP016353_4	4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175828-2175860	33	MN586049	Gordonia phage Yarn, complete genome	7420-7452	7	0.788
NZ_CP016353_4	4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175828-2175860	33	MN586036	Gordonia phage AndPeggy, complete genome	7426-7458	7	0.788
NZ_CP016353_5	5.3|2185544|31|NZ_CP016353|CRISPRCasFinder	2185544-2185574	31	NZ_CP022418	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-3, complete sequence	69823-69853	7	0.774
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	491332-491363	7	0.781
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	897902-897933	7	0.781
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	185646-185677	7	0.781
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	233723-233754	7	0.781
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	70954-70985	7	0.781
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	129509-129540	7	0.781
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	202092-202123	7	0.781
NZ_CP016353_5	5.5|2185665|32|NZ_CP016353|CRISPRCasFinder	2185665-2185696	32	NZ_LR594663	Variovorax sp. RA8 plasmid 2	360349-360380	7	0.781
NZ_CP016353_5	5.10|2185970|32|NZ_CP016353|CRISPRCasFinder	2185970-2186001	32	NZ_CP045481	Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence	11733-11764	7	0.781
NZ_CP016353_5	5.11|2186031|32|NZ_CP016353|CRISPRCasFinder	2186031-2186062	32	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	837490-837521	7	0.781
NZ_CP016353_5	5.21|2185970|33|NZ_CP016353|CRT	2185970-2186002	33	NZ_CP045481	Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence	11732-11764	7	0.788
NZ_CP016353_5	5.30|2185977|33|NZ_CP016353|PILER-CR	2185977-2186009	33	NZ_CP045481	Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence	11732-11764	7	0.788
NZ_CP016353_6	6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT	2666042-2666074	33	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	116780-116812	7	0.788
NZ_CP016353_6	6.9|2666225|33|NZ_CP016353|CRISPRCasFinder,CRT	2666225-2666257	33	MF668280	Mycobacterium phage Phabba, complete genome	119284-119316	7	0.788
NZ_CP016353_6	6.15|2666047|34|NZ_CP016353|PILER-CR	2666047-2666080	34	MN234170	Mycobacterium phage MalagasyRose, complete genome	2809-2842	7	0.794
NZ_CP016353_6	6.17|2666169|34|NZ_CP016353|PILER-CR	2666169-2666202	34	AP014065	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C13-MedDCM-OCT-S36-C38, *** SEQUENCING IN PROGRESS ***	17604-17637	7	0.794
NZ_CP016353_6	6.18|2666230|34|NZ_CP016353|PILER-CR	2666230-2666263	34	MF668280	Mycobacterium phage Phabba, complete genome	119283-119316	7	0.794
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1311424-1311455	7	0.781
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1311424-1311455	7	0.781
NZ_CP016353_11	11.13|6222544|35|NZ_CP016353|CRT	6222544-6222578	35	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	429371-429405	7	0.8
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	AP017627	Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome	119988-120020	8	0.758
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	153971-154003	8	0.758
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	NZ_CP006368	Aureimonas sp. AU20 plasmid pAU20a, complete sequence	479540-479572	8	0.758
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	NZ_CP006370	Aureimonas sp. AU20 plasmid pAU20c, complete sequence	28713-28745	8	0.758
NZ_CP016353_4	4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT	2175278-2175310	33	NC_009426	Novosphingobium aromaticivorans DSM 12444 plasmid pNL1, complete sequence	145548-145580	8	0.758
NZ_CP016353_4	4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT	2175278-2175310	33	NC_002033	Novosphingobium aromaticivorans plasmid pNL1, complete sequence	88937-88969	8	0.758
NZ_CP016353_4	4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175828-2175860	33	NZ_CP019083	Paludisphaera borealis strain PX4 plasmid PALBO1, complete sequence	85088-85120	8	0.758
NZ_CP016353_5	5.3|2185544|31|NZ_CP016353|CRISPRCasFinder	2185544-2185574	31	MT701587	Burkholderia phage Magia, complete genome	39551-39581	8	0.742
NZ_CP016353_5	5.6|2185726|32|NZ_CP016353|CRISPRCasFinder	2185726-2185757	32	KJ025957	Serratia phage PS2, complete genome	100391-100422	8	0.75
NZ_CP016353_5	5.8|2185848|32|NZ_CP016353|CRISPRCasFinder	2185848-2185879	32	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	193231-193262	8	0.75
NZ_CP016353_5	5.14|2185544|32|NZ_CP016353|CRT	2185544-2185575	32	NZ_CP022418	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-3, complete sequence	69823-69854	8	0.75
NZ_CP016353_5	5.15|2185604|33|NZ_CP016353|CRT	2185604-2185636	33	MT778840	Rhizobium phage P11VFA, complete genome	108148-108180	8	0.758
NZ_CP016353_5	5.15|2185604|33|NZ_CP016353|CRT	2185604-2185636	33	KF614509	Rhizobium phage vB_RleS_L338C, complete genome	92778-92810	8	0.758
NZ_CP016353_5	5.22|2186031|33|NZ_CP016353|CRT	2186031-2186063	33	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	837490-837522	8	0.758
NZ_CP016353_5	5.24|2185611|33|NZ_CP016353|PILER-CR	2185611-2185643	33	MT778840	Rhizobium phage P11VFA, complete genome	108148-108180	8	0.758
NZ_CP016353_5	5.24|2185611|33|NZ_CP016353|PILER-CR	2185611-2185643	33	KF614509	Rhizobium phage vB_RleS_L338C, complete genome	92778-92810	8	0.758
NZ_CP016353_5	5.31|2186038|33|NZ_CP016353|PILER-CR	2186038-2186070	33	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	837490-837522	8	0.758
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	MN183284	Microbacterium phage Mashley, complete genome	14311-14344	8	0.765
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NC_047973	Microbacterium phage Hyperion, complete genome	14500-14533	8	0.765
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NC_008383	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL8, complete sequence	121084-121117	8	0.765
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NZ_CP050090	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b4, complete sequence	39383-39416	8	0.765
NZ_CP016353_6	6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT	2666042-2666074	33	NC_022050	Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence	150584-150616	8	0.758
NZ_CP016353_6	6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT	2666042-2666074	33	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	63501-63533	8	0.758
NZ_CP016353_6	6.8|2666164|33|NZ_CP016353|CRISPRCasFinder,CRT	2666164-2666196	33	AP014371	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S42-C166, *** SEQUENCING IN PROGRESS ***	261-293	8	0.758
NZ_CP016353_6	6.15|2666047|34|NZ_CP016353|PILER-CR	2666047-2666080	34	NC_022050	Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence	150584-150617	8	0.765
NZ_CP016353_6	6.15|2666047|34|NZ_CP016353|PILER-CR	2666047-2666080	34	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	116779-116812	8	0.765
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	429371-429402	8	0.75
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	981097-981128	8	0.75
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	MK801721	Gordonia phage William, complete genome	247-278	8	0.75
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	MK814757	Gordonia phage Fairfaxidum, complete genome	247-278	8	0.75
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	MN234161	Gordonia phage Toast, complete genome	247-278	8	0.75
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	429371-429402	8	0.75
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	981097-981128	8	0.75
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	MK801721	Gordonia phage William, complete genome	247-278	8	0.75
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	MK814757	Gordonia phage Fairfaxidum, complete genome	247-278	8	0.75
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	MN234161	Gordonia phage Toast, complete genome	247-278	8	0.75
NZ_CP016353_11	11.13|6222544|35|NZ_CP016353|CRT	6222544-6222578	35	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	981094-981128	8	0.771
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	393887-393919	9	0.727
NZ_CP016353_4	4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT	2175278-2175310	33	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	805187-805219	9	0.727
NZ_CP016353_4	4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT	2175278-2175310	33	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	130342-130374	9	0.727
NZ_CP016353_4	4.7|2175522|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175522-2175554	33	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	64397-64429	9	0.727
NZ_CP016353_5	5.1|2185421|32|NZ_CP016353|CRISPRCasFinder	2185421-2185452	32	NZ_CP042264	Litoreibacter sp. LN3S51 plasmid unnamed3, complete sequence	68547-68578	9	0.719
NZ_CP016353_5	5.1|2185421|32|NZ_CP016353|CRISPRCasFinder	2185421-2185452	32	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	491989-492020	9	0.719
NZ_CP016353_5	5.1|2185421|32|NZ_CP016353|CRISPRCasFinder	2185421-2185452	32	NZ_CP018784	Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence	343569-343600	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP014514	Frondihabitans sp. PAMC 28766 strain SR6 plasmid 1, complete sequence	41537-41568	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP014514	Frondihabitans sp. PAMC 28766 strain SR6 plasmid 1, complete sequence	182681-182712	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP014516	Frondihabitans sp. PAMC 28766 strain SR6 plasmid 3, complete sequence	51226-51257	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	231643-231674	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	1182624-1182655	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	MT778840	Rhizobium phage P11VFA, complete genome	108149-108180	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	KF614509	Rhizobium phage vB_RleS_L338C, complete genome	92778-92809	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	MT152150	Pseudomonas phage 8P, complete genome	18620-18651	9	0.719
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	257412-257443	9	0.719
NZ_CP016353_5	5.6|2185726|32|NZ_CP016353|CRISPRCasFinder	2185726-2185757	32	JX306041	Stenotrophomonas phage IME13, complete genome	78794-78825	9	0.719
NZ_CP016353_5	5.7|2185787|32|NZ_CP016353|CRISPRCasFinder	2185787-2185818	32	MK095606	Pantoea phage vB_PagS_AAS23, complete genome	21759-21790	9	0.719
NZ_CP016353_5	5.9|2185909|32|NZ_CP016353|CRISPRCasFinder	2185909-2185940	32	NZ_CP014310	Burkholderia sp. PAMC 26561 plasmid unnamed3, complete sequence	204950-204981	9	0.719
NZ_CP016353_5	5.10|2185970|32|NZ_CP016353|CRISPRCasFinder	2185970-2186001	32	NC_006907	Leptospirillum ferrooxidans plasmid p49879.1, complete sequence	24204-24235	9	0.719
NZ_CP016353_5	5.10|2185970|32|NZ_CP016353|CRISPRCasFinder	2185970-2186001	32	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	994893-994924	9	0.719
NZ_CP016353_5	5.11|2186031|32|NZ_CP016353|CRISPRCasFinder	2186031-2186062	32	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	227232-227263	9	0.719
NZ_CP016353_5	5.19|2185848|33|NZ_CP016353|CRT	2185848-2185880	33	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	193231-193263	9	0.727
NZ_CP016353_5	5.28|2185855|33|NZ_CP016353|PILER-CR	2185855-2185887	33	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	193231-193263	9	0.727
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	MK801723	Gordonia phage Coeur, complete genome	4908-4941	9	0.735
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NC_004963	Mycobacterium celatum plasmid pCLP, complete sequence	14496-14529	9	0.735
NZ_CP016353_6	6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT	2666042-2666074	33	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4602134-4602166	9	0.727
NZ_CP016353_6	6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT	2666042-2666074	33	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	521990-522022	9	0.727
NZ_CP016353_6	6.8|2666164|33|NZ_CP016353|CRISPRCasFinder,CRT	2666164-2666196	33	NC_015146	Pseudarthrobacter phenanthrenivorans Sphe3 plasmid pASPHE301, complete sequence	141478-141510	9	0.727
NZ_CP016353_6	6.15|2666047|34|NZ_CP016353|PILER-CR	2666047-2666080	34	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	521990-522023	9	0.735
NZ_CP016353_6	6.15|2666047|34|NZ_CP016353|PILER-CR	2666047-2666080	34	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	63501-63534	9	0.735
NZ_CP016353_6	6.17|2666169|34|NZ_CP016353|PILER-CR	2666169-2666202	34	AP014371	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S42-C166, *** SEQUENCING IN PROGRESS ***	260-293	9	0.735
NZ_CP016353_9	9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT	4403470-4403502	33	NZ_LR594660	Variovorax sp. PBL-H6 plasmid 2	613764-613796	9	0.727
NZ_CP016353_9	9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT	4403470-4403502	33	NZ_LR594667	Variovorax sp. SRS16 plasmid 2	224393-224425	9	0.727
NZ_CP016353_9	9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT	4403470-4403502	33	NZ_LR594690	Variovorax sp. WDL1 plasmid 2	226446-226478	9	0.727
NZ_CP016353_9	9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT	4403470-4403502	33	NZ_LR594672	Variovorax sp. PBL-E5 plasmid 2	224393-224425	9	0.727
NZ_CP016353_11	11.2|6222421|33|NZ_CP016353|PILER-CR,CRISPRCasFinder	6222421-6222453	33	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	266144-266176	9	0.727
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	190937-190968	9	0.719
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	183381-183412	9	0.719
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	190937-190968	9	0.719
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	183381-183412	9	0.719
NZ_CP016353_11	11.9|6222665|33|NZ_CP016353|CRISPRCasFinder	6222665-6222697	33	NC_019540	Salinivibrio phage CW02, complete genome	26930-26962	9	0.727
NZ_CP016353_12	12.3|6488268|32|NZ_CP016353|CRISPRCasFinder	6488268-6488299	32	NC_009806	Kineococcus radiotolerans SRS30216 = ATCC BAA-149 plasmid pKRAD01, complete sequence	125635-125666	9	0.719
NZ_CP016353_2	2.2|1413259|33|NZ_CP016353|CRISPRCasFinder	1413259-1413291	33	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	129570-129602	10	0.697
NZ_CP016353_4	4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175828-2175860	33	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	150482-150514	10	0.697
NZ_CP016353_4	4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175950-2175982	33	MN694527	Marine virus AFVG_250M568, complete genome	11619-11651	10	0.697
NZ_CP016353_4	4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175950-2175982	33	MN694027	Marine virus AFVG_250M455, complete genome	11627-11659	10	0.697
NZ_CP016353_4	4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175950-2175982	33	MN694088	Marine virus AFVG_250M454, complete genome	40009-40041	10	0.697
NZ_CP016353_4	4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR	2175950-2175982	33	MN694007	Marine virus AFVG_250M456, complete genome	40414-40446	10	0.697
NZ_CP016353_5	5.1|2185421|32|NZ_CP016353|CRISPRCasFinder	2185421-2185452	32	NZ_CP007510	Pseudomonas stutzeri strain 19SMN4 plasmid pLIB119, complete plasmid	92425-92456	10	0.688
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	MT498059	Gordonia phage Doggs, complete genome	20308-20339	10	0.688
NZ_CP016353_5	5.9|2185909|32|NZ_CP016353|CRISPRCasFinder	2185909-2185940	32	MN694142	Marine virus AFVG_250M416, complete genome	56367-56398	10	0.688
NZ_CP016353_5	5.10|2185970|32|NZ_CP016353|CRISPRCasFinder	2185970-2186001	32	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1073826-1073857	10	0.688
NZ_CP016353_5	5.10|2185970|32|NZ_CP016353|CRISPRCasFinder	2185970-2186001	32	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1316423-1316454	10	0.688
NZ_CP016353_5	5.10|2185970|32|NZ_CP016353|CRISPRCasFinder	2185970-2186001	32	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	880198-880229	10	0.688
NZ_CP016353_5	5.11|2186031|32|NZ_CP016353|CRISPRCasFinder	2186031-2186062	32	NZ_CP013635	Rhizobium sp. N324 plasmid pRspN324e, complete sequence	323039-323070	10	0.688
NZ_CP016353_5	5.12|2185421|33|NZ_CP016353|CRT	2185421-2185453	33	NZ_CP042264	Litoreibacter sp. LN3S51 plasmid unnamed3, complete sequence	68546-68578	10	0.697
NZ_CP016353_5	5.15|2185604|33|NZ_CP016353|CRT	2185604-2185636	33	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	231643-231675	10	0.697
NZ_CP016353_5	5.15|2185604|33|NZ_CP016353|CRT	2185604-2185636	33	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	1182624-1182656	10	0.697
NZ_CP016353_5	5.15|2185604|33|NZ_CP016353|CRT	2185604-2185636	33	MT152150	Pseudomonas phage 8P, complete genome	18620-18652	10	0.697
NZ_CP016353_5	5.21|2185970|33|NZ_CP016353|CRT	2185970-2186002	33	NC_006907	Leptospirillum ferrooxidans plasmid p49879.1, complete sequence	24203-24235	10	0.697
NZ_CP016353_5	5.21|2185970|33|NZ_CP016353|CRT	2185970-2186002	33	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	994893-994925	10	0.697
NZ_CP016353_5	5.24|2185611|33|NZ_CP016353|PILER-CR	2185611-2185643	33	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	231643-231675	10	0.697
NZ_CP016353_5	5.24|2185611|33|NZ_CP016353|PILER-CR	2185611-2185643	33	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	1182624-1182656	10	0.697
NZ_CP016353_5	5.24|2185611|33|NZ_CP016353|PILER-CR	2185611-2185643	33	MT152150	Pseudomonas phage 8P, complete genome	18620-18652	10	0.697
NZ_CP016353_5	5.30|2185977|33|NZ_CP016353|PILER-CR	2185977-2186009	33	NC_006907	Leptospirillum ferrooxidans plasmid p49879.1, complete sequence	24203-24235	10	0.697
NZ_CP016353_5	5.30|2185977|33|NZ_CP016353|PILER-CR	2185977-2186009	33	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	994893-994925	10	0.697
NZ_CP016353_6	6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT	2666042-2666074	33	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	438347-438379	10	0.697
NZ_CP016353_6	6.15|2666047|34|NZ_CP016353|PILER-CR	2666047-2666080	34	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4602134-4602167	10	0.706
NZ_CP016353_6	6.17|2666169|34|NZ_CP016353|PILER-CR	2666169-2666202	34	NC_015146	Pseudarthrobacter phenanthrenivorans Sphe3 plasmid pASPHE301, complete sequence	141477-141510	10	0.706
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	NZ_CP019641	Planococcus sp. Y42 plasmid unnamed1, complete sequence	214491-214522	10	0.688
NZ_CP016353_11	11.4|6222549|32|NZ_CP016353|PILER-CR	6222549-6222580	32	NZ_LR594668	Variovorax sp. SRS16 plasmid 3	175656-175687	10	0.688
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	NZ_CP019641	Planococcus sp. Y42 plasmid unnamed1, complete sequence	214491-214522	10	0.688
NZ_CP016353_11	11.7|6222544|32|NZ_CP016353|CRISPRCasFinder	6222544-6222575	32	NZ_LR594668	Variovorax sp. SRS16 plasmid 3	175656-175687	10	0.688
NZ_CP016353_11	11.11|6222421|36|NZ_CP016353|CRT	6222421-6222456	36	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	266144-266179	10	0.722
NZ_CP016353_11	11.13|6222544|35|NZ_CP016353|CRT	6222544-6222578	35	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1311424-1311458	10	0.714
NZ_CP016353_12	12.2|6488207|32|NZ_CP016353|CRISPRCasFinder	6488207-6488238	32	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	410769-410800	10	0.688
NZ_CP016353_12	12.2|6488207|32|NZ_CP016353|CRISPRCasFinder	6488207-6488238	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	587249-587280	10	0.688
NZ_CP016353_12	12.2|6488207|32|NZ_CP016353|CRISPRCasFinder	6488207-6488238	32	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	410785-410816	10	0.688
NZ_CP016353_12	12.2|6488207|32|NZ_CP016353|CRISPRCasFinder	6488207-6488238	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	710930-710961	10	0.688
NZ_CP016353_12	12.2|6488207|32|NZ_CP016353|CRISPRCasFinder	6488207-6488238	32	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	682774-682805	10	0.688
NZ_CP016353_5	5.4|2185604|32|NZ_CP016353|CRISPRCasFinder	2185604-2185635	32	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	888426-888457	11	0.656
NZ_CP016353_6	6.1|2665734|33|NZ_CP016353|CRISPRCasFinder,CRT	2665734-2665766	33	NC_022358	Sulfuricella denitrificans skB26 plasmid pSCD, complete sequence	27909-27941	11	0.667
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NC_019018	Mycobacterium marinum DL240490 plasmid pMUM003, complete sequence	87577-87610	11	0.676
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NC_011355	Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence	34352-34385	11	0.676
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NZ_AP017625	Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence	29255-29288	11	0.676
NZ_CP016353_6	6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT	2665795-2665828	34	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1607406-1607439	11	0.676
NZ_CP016353_6	6.15|2666047|34|NZ_CP016353|PILER-CR	2666047-2666080	34	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	438346-438379	11	0.676

1. spacer 7.2|3008316|25|NZ_CP016353|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 3, identity: 0.88

ctcctatcgctccaccaccagcgcg	CRISPR spacer
gtcctcgcgctccaccaccagcgcg	Protospacer
 ****  ******************

2. spacer 7.2|3008316|25|NZ_CP016353|CRISPRCasFinder matches to NZ_CP012917 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p3, complete sequence) position: , mismatch: 3, identity: 0.88

ctcctatcgctccaccaccagcgcg	CRISPR spacer
gtcctcgcgctccaccaccagcgcg	Protospacer
 ****  ******************

3. spacer 7.2|3008316|25|NZ_CP016353|CRISPRCasFinder matches to NZ_CP032343 (Azospirillum brasilense strain MTCC4038 plasmid p4, complete sequence) position: , mismatch: 3, identity: 0.88

ctcctatcgctccaccaccagcgcg	CRISPR spacer
gtcctcgcgctccaccaccagcgcg	Protospacer
 ****  ******************

4. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to MH271312 (Microbacterium phage RobsFeet, complete genome) position: , mismatch: 5, identity: 0.848

tcgactg-cgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
-cgccagccgaaggccacgaccgcgaaggcggcg	Protospacer
 ** * * ******* *************** **

5. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to NC_047988 (Microbacterium phage Metamorphoo, complete genome) position: , mismatch: 5, identity: 0.848

tcgactg-cgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
-cgccagccgaaggccacgaccgcgaaggcggcg	Protospacer
 ** * * ******* *************** **

6. spacer 5.11|2186031|32|NZ_CP016353|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.812

---gatcctggggccgaccggctcgccttgctcca	CRISPR spacer
gcggatc---gggccggccggctcgccgtgctcga	Protospacer
   ****   ******.********** ***** *

7. spacer 6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT matches to MN234170 (Mycobacterium phage MalagasyRose, complete genome) position: , mismatch: 6, identity: 0.818

--gctggctgacggtcgatgaggcgacgatcaacg	CRISPR spacer
gcgttggtt--cggtcgctgaggcgacgttcaacg	Protospacer
  *.***.*  ****** ********** ******

8. spacer 6.8|2666164|33|NZ_CP016353|CRISPRCasFinder,CRT matches to AP014065 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C13-MedDCM-OCT-S36-C38, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.818

tgccggacaccagcaccacaccggtaccgccgg	CRISPR spacer
ttctggacaccagcaccacaccggcaacgctga	Protospacer
* *.********************.* ***.*.

9. spacer 9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

ctggtcctg--aagctggtccccgagctggccccg	CRISPR spacer
--ggccccggcaagctcgtcgccgagctggccccg	Protospacer
  **.**.*  ***** *** **************

10. spacer 9.5|4403714|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT matches to AP017924 (Ralstonia phage RP12 DNA, complete genome) position: , mismatch: 6, identity: 0.818

ttactgagcgcaccagcctggtca--accgtgcct	CRISPR spacer
ttactgggcgaaccagcctggtcatgaccgagt--	Protospacer
******.*** *************  **** *.  

11. spacer 9.5|4403714|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT matches to AP017925 (Ralstonia phage RP31 DNA, complete genome) position: , mismatch: 6, identity: 0.818

ttactgagcgcaccagcctggtca--accgtgcct	CRISPR spacer
ttactgggcgaaccagcctggtcatgaccgagt--	Protospacer
******.*** *************  **** *.  

12. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to NZ_CP053567 (Pseudonocardia sp. Gen01 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.788

tcgac-tgcgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
-cgccaggcgaaggtgccgaccgcgaaggcgagg	Protospacer
 ** *  *******.* **************  *

13. spacer 4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NZ_KM017071 (Sphingomonas sp. JE1 plasmid pJE1, complete sequence) position: , mismatch: 7, identity: 0.788

ctggagaaggacccggcgcaggccgagcgcttc	CRISPR spacer
cagcaggtcgacctcgcgcaggccgagcgcttc	Protospacer
* * **.  ****. ******************

14. spacer 4.10|2175705|34|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LN832560 (Paracoccus aminovorans isolate JCM7685 plasmid II, complete sequence) position: , mismatch: 7, identity: 0.794

ggggcttttctggctgtgctgcacggc-atgcggc	CRISPR spacer
gccgcgtttctggctgtgctggacggctatacgc-	Protospacer
*  ** *************** ***** **.**  

15. spacer 4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.788

atgaagatggccgtcctcaaggtcgtctccgag	CRISPR spacer
aacaagatcgccggcctcaaggtcgtcgcgcag	Protospacer
*  ***** **** ************* *  **

16. spacer 4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to MN586049 (Gordonia phage Yarn, complete genome) position: , mismatch: 7, identity: 0.788

atgaagatggccgtcctcaaggtcgtctccgag	CRISPR spacer
agggtgctgcccgtcctcaaggtcgtcaccgcg	Protospacer
* *. * ** ***************** *** *

17. spacer 4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to MN586036 (Gordonia phage AndPeggy, complete genome) position: , mismatch: 7, identity: 0.788

atgaagatggccgtcctcaaggtcgtctccgag	CRISPR spacer
agggtgctgcccgtcctcaaggtcgtcaccgcg	Protospacer
* *. * ** ***************** *** *

18. spacer 5.3|2185544|31|NZ_CP016353|CRISPRCasFinder matches to NZ_CP022418 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-3, complete sequence) position: , mismatch: 7, identity: 0.774

tggagcggtggcgcggcgtcggactgagggc	CRISPR spacer
gcgagcggtggcggggcgtcggcctggaggt	Protospacer
  *********** ******** ***..**.

19. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.781

tcggagggcaccggcgcgttgatctcggcaac--	CRISPR spacer
acggcgggcgccggcgcgttgatcc--gcagcgt	Protospacer
 *** ****.**************.  ***.*  

20. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 7, identity: 0.781

tcggagggcaccggcgcgttgatctcggcaac--	CRISPR spacer
acggcgggcgccggcgcgttgatcc--gcagcgt	Protospacer
 *** ****.**************.  ***.*  

21. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 7, identity: 0.781

tcggagggcaccggcgcgttgatctcggcaac--	CRISPR spacer
acggcgggcgccggcgcgttgatcc--gcagcgt	Protospacer
 *** ****.**************.  ***.*  

22. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.781

tcggagggcaccggcgcgttgatctcggcaac--	CRISPR spacer
acggcgggcgccggcgcgttgatcc--gcagcgt	Protospacer
 *** ****.**************.  ***.*  

23. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.781

tcggagggcaccggcgcgttgatctcggcaac--	CRISPR spacer
acggcgggcgccggcgcgttgatcc--gcagcgt	Protospacer
 *** ****.**************.  ***.*  

24. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.781

tcggagggcaccggcgcgttgatctcggcaac--	CRISPR spacer
acggcgggcgccggcgcgttgatcc--gcagcgt	Protospacer
 *** ****.**************.  ***.*  

25. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

tcggagggcaccggcgcgttgatctcggcaac--	CRISPR spacer
acggcgggcgccggcgcgttgatcc--gcagcgt	Protospacer
 *** ****.**************.  ***.*  

26. spacer 5.5|2185665|32|NZ_CP016353|CRISPRCasFinder matches to NZ_LR594663 (Variovorax sp. RA8 plasmid 2) position: , mismatch: 7, identity: 0.781

gaccgcgaatacgtgcgcgggctcatggccga	CRISPR spacer
ggccgcgaattcgtgcgcggcctcacccgcga	Protospacer
*.******** ********* ****.   ***

27. spacer 5.10|2185970|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP045481 (Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence) position: , mismatch: 7, identity: 0.781

gtgtcccgaaccactaccgcgcgtcctatgtg	CRISPR spacer
gcgtggtcaaccactaccgggcgtcctacgtg	Protospacer
*.**  . *********** ********.***

28. spacer 5.11|2186031|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

---gatcctggggccgaccggctcgccttgctcca	CRISPR spacer
cgcgagc---ggaccgaccggctcgccttgatccg	Protospacer
   ** *   **.***************** ***.

29. spacer 5.21|2185970|33|NZ_CP016353|CRT matches to NZ_CP045481 (Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence) position: , mismatch: 7, identity: 0.788

gtgtcccgaaccactaccgcgcgtcctatgtgg	CRISPR spacer
gcgtggtcaaccactaccgggcgtcctacgtgg	Protospacer
*.**  . *********** ********.****

30. spacer 5.30|2185977|33|NZ_CP016353|PILER-CR matches to NZ_CP045481 (Amycolatopsis sp. YIM 10 plasmid pAmyYIM10, complete sequence) position: , mismatch: 7, identity: 0.788

gtgtcccgaaccactaccgcgcgtcctatgtgg	CRISPR spacer
gcgtggtcaaccactaccgggcgtcctacgtgg	Protospacer
*.**  . *********** ********.****

31. spacer 6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 7, identity: 0.788

-gctggctgacggtcgatgaggcgacgatcaacg	CRISPR spacer
cggtgaacg-cggtcgatgaggcggtgatcaacg	Protospacer
 * **. .* **************..********

32. spacer 6.9|2666225|33|NZ_CP016353|CRISPRCasFinder,CRT matches to MF668280 (Mycobacterium phage Phabba, complete genome) position: , mismatch: 7, identity: 0.788

ggtgtctctctcggtgctcaccggtcctccagc	CRISPR spacer
cgtggtggtctcggtgctcactagtcctccagc	Protospacer
 *** .  *************..**********

33. spacer 6.15|2666047|34|NZ_CP016353|PILER-CR matches to MN234170 (Mycobacterium phage MalagasyRose, complete genome) position: , mismatch: 7, identity: 0.794

--gctggctgacggtcgatgaggcgacgatcaacgg	CRISPR spacer
gcgttggtt--cggtcgctgaggcgacgttcaacga	Protospacer
  *.***.*  ****** ********** ******.

34. spacer 6.17|2666169|34|NZ_CP016353|PILER-CR matches to AP014065 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C13-MedDCM-OCT-S36-C38, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.794

tgccggacaccagcaccacaccggtaccgccggg	CRISPR spacer
ttctggacaccagcaccacaccggcaacgctgaa	Protospacer
* *.********************.* ***.*..

35. spacer 6.18|2666230|34|NZ_CP016353|PILER-CR matches to MF668280 (Mycobacterium phage Phabba, complete genome) position: , mismatch: 7, identity: 0.794

ggtgtctctctcggtgctcaccggtcctccagcg	CRISPR spacer
cgtggtggtctcggtgctcactagtcctccagcg	Protospacer
 *** .  *************..***********

36. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 7, identity: 0.781

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
tgtcagccagcggatcatcgaccagatcgaca	Protospacer
..************* ******* *** * * 

37. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 7, identity: 0.781

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
tgtcagccagcggatcatcgaccagatcgaca	Protospacer
..************* ******* *** * * 

38. spacer 11.13|6222544|35|NZ_CP016353|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.8

catcagccagcggatgatcgacccgatggtctgtg-	CRISPR spacer
ctgcagcccgcggatgatcgacgcgat-gtcggcgg	Protospacer
*  ***** ************* **** *** *.* 

39. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to AP017627 (Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome) position: , mismatch: 8, identity: 0.758

tcgactgcgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
gcggtgcggaaggcgtcgaccgcgaaggggtcg	Protospacer
 **..   ******* ************ ****

40. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 8, identity: 0.758

tcgactgcgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
tcgactgcgagggcgccgaccgcgacgtcaaga	Protospacer
**********.**** ********* * *.  .

41. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to NZ_CP006368 (Aureimonas sp. AU20 plasmid pAU20a, complete sequence) position: , mismatch: 8, identity: 0.758

tcgactgcgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
cgcacttcggaggcgacgaccgcgaagcctttg	Protospacer
.  *** **.***************** * *.*

42. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to NZ_CP006370 (Aureimonas sp. AU20 plasmid pAU20c, complete sequence) position: , mismatch: 8, identity: 0.758

tcgactgcgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
cgcacttcggaggcgacgaccgcgaagcccttg	Protospacer
.  *** **.***************** * *.*

43. spacer 4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_009426 (Novosphingobium aromaticivorans DSM 12444 plasmid pNL1, complete sequence) position: , mismatch: 8, identity: 0.758

ctggagaaggacccggcgcaggccgagcgcttc	CRISPR spacer
cgcgccaaggacccggcgcaggctgaacgccta	Protospacer
*  *  *****************.**.***.* 

44. spacer 4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_002033 (Novosphingobium aromaticivorans plasmid pNL1, complete sequence) position: , mismatch: 8, identity: 0.758

ctggagaaggacccggcgcaggccgagcgcttc	CRISPR spacer
cgcgccaaggacccggcgcaggctgaacgccta	Protospacer
*  *  *****************.**.***.* 

45. spacer 4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019083 (Paludisphaera borealis strain PX4 plasmid PALBO1, complete sequence) position: , mismatch: 8, identity: 0.758

atgaagatggccgtcctcaaggtcgtctccgag	CRISPR spacer
aatcggctggtcgtcctcaaggtcctctccgac	Protospacer
*   .* ***.************* ******* 

46. spacer 5.3|2185544|31|NZ_CP016353|CRISPRCasFinder matches to MT701587 (Burkholderia phage Magia, complete genome) position: , mismatch: 8, identity: 0.742

tggagcggtggcgcggcgtcggactgagggc	CRISPR spacer
tggggcggtggcgcggcgtcggtgtcgcgtt	Protospacer
***.******************  * . * .

47. spacer 5.6|2185726|32|NZ_CP016353|CRISPRCasFinder matches to KJ025957 (Serratia phage PS2, complete genome) position: , mismatch: 8, identity: 0.75

tacatcaagggaatcaacacctggaagaacca	CRISPR spacer
ttgaccaagtgaatcagcacctggaagagacg	Protospacer
*  *.**** ******.***********. *.

48. spacer 5.8|2185848|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 8, identity: 0.75

gatcgtcgatggtgtccggtcggtcgtagaga	CRISPR spacer
cgacgaagatgttgtcgggtcggtcgtagagt	Protospacer
 . **  **** **** ************** 

49. spacer 5.14|2185544|32|NZ_CP016353|CRT matches to NZ_CP022418 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-3, complete sequence) position: , mismatch: 8, identity: 0.75

tggagcggtggcgcggcgtcggactgagggcg	CRISPR spacer
gcgagcggtggcggggcgtcggcctggaggtc	Protospacer
  *********** ******** ***..**. 

50. spacer 5.15|2185604|33|NZ_CP016353|CRT matches to MT778840 (Rhizobium phage P11VFA, complete genome) position: , mismatch: 8, identity: 0.758

tcggagggcaccggcgcgttgatctcggcaacg-	CRISPR spacer
cggcagggcagcggcgcgttgatct-gggagcac	Protospacer
. * ****** ************** ** *.*. 

51. spacer 5.15|2185604|33|NZ_CP016353|CRT matches to KF614509 (Rhizobium phage vB_RleS_L338C, complete genome) position: , mismatch: 8, identity: 0.758

tcggagggcaccggcgcgttgatctcggcaacg-	CRISPR spacer
cggcagggcagcggcgcgttgatct-gggagcac	Protospacer
. * ****** ************** ** *.*. 

52. spacer 5.22|2186031|33|NZ_CP016353|CRT matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

---gatcctggggccgaccggctcgccttgctccag	CRISPR spacer
cgcgagc---ggaccgaccggctcgccttgatccgc	Protospacer
   ** *   **.***************** ***. 

53. spacer 5.24|2185611|33|NZ_CP016353|PILER-CR matches to MT778840 (Rhizobium phage P11VFA, complete genome) position: , mismatch: 8, identity: 0.758

tcggagggcaccggcgcgttgatctcggcaacg-	CRISPR spacer
cggcagggcagcggcgcgttgatct-gggagcac	Protospacer
. * ****** ************** ** *.*. 

54. spacer 5.24|2185611|33|NZ_CP016353|PILER-CR matches to KF614509 (Rhizobium phage vB_RleS_L338C, complete genome) position: , mismatch: 8, identity: 0.758

tcggagggcaccggcgcgttgatctcggcaacg-	CRISPR spacer
cggcagggcagcggcgcgttgatct-gggagcac	Protospacer
. * ****** ************** ** *.*. 

55. spacer 5.31|2186038|33|NZ_CP016353|PILER-CR matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

---gatcctggggccgaccggctcgccttgctccag	CRISPR spacer
cgcgagc---ggaccgaccggctcgccttgatccgc	Protospacer
   ** *   **.***************** ***. 

56. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to MN183284 (Microbacterium phage Mashley, complete genome) position: , mismatch: 8, identity: 0.765

gctcgtcggatgtcggccagctcggcgcgagcgg	CRISPR spacer
tccttgccgatgtcggcgagcttggcgcgagcgg	Protospacer
 *..  * ********* ****.***********

57. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_047973 (Microbacterium phage Hyperion, complete genome) position: , mismatch: 8, identity: 0.765

gctcgtcggatgtcggccagctcggcgcgagcgg	CRISPR spacer
tccttgccgatgtcggcgagcttggcgcgagcgg	Protospacer
 *..  * ********* ****.***********

58. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_008383 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL8, complete sequence) position: , mismatch: 8, identity: 0.765

gctcgtcg--gatgtcggccagctcggcgcgagcgg	CRISPR spacer
--tcggcaatgatgacggccagctcggcgcgcgcca	Protospacer
  *** *.  **** **************** ** .

59. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NZ_CP050090 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b4, complete sequence) position: , mismatch: 8, identity: 0.765

gctcgtcg--gatgtcggccagctcggcgcgagcgg	CRISPR spacer
--tcggcaatgatgacggccagctcggcgcgcgcca	Protospacer
  *** *.  **** **************** ** .

60. spacer 6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_022050 (Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence) position: , mismatch: 8, identity: 0.758

gctggctgacggtcgatgaggcgacgatcaacg	CRISPR spacer
gcgaaggcacggtcgacgaggcgacgatcaccg	Protospacer
** ..   ********.************* **

61. spacer 6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 8, identity: 0.758

gctggctgacggtcgatgaggcgacgatcaacg	CRISPR spacer
gctggctgacggtcgaataggcgagcctcgcct	Protospacer
****************  ******   **. * 

62. spacer 6.8|2666164|33|NZ_CP016353|CRISPRCasFinder,CRT matches to AP014371 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S42-C166, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.758

tgccggacaccagcaccacaccggtaccgccgg	CRISPR spacer
ttttagacaccagcaccacaccggcaacgctga	Protospacer
* ...*******************.* ***.*.

63. spacer 6.15|2666047|34|NZ_CP016353|PILER-CR matches to NC_022050 (Paracoccus aminophilus JCM 7686 plasmid pAMI8, complete sequence) position: , mismatch: 8, identity: 0.765

gctggctgacggtcgatgaggcgacgatcaacgg	CRISPR spacer
gcgaaggcacggtcgacgaggcgacgatcaccgg	Protospacer
** ..   ********.************* ***

64. spacer 6.15|2666047|34|NZ_CP016353|PILER-CR matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 8, identity: 0.765

-gctggctgacggtcgatgaggcgacgatcaacgg	CRISPR spacer
cggtgaacg-cggtcgatgaggcggtgatcaacgc	Protospacer
 * **. .* **************..******** 

65. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
ctgcagcccgcggatgatcgacgcgatgtcgg	Protospacer
*  ***** ************* ***** .  

66. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
tgtcagccagcggatcatcgaccagatcgata	Protospacer
..************* ******* *** * . 

67. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to MK801721 (Gordonia phage William, complete genome) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
actccgcgagcggatgatcgacccgaacctcg	Protospacer
  ** ** ******************   ** 

68. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to MK814757 (Gordonia phage Fairfaxidum, complete genome) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
actccgcgagcggatgatcgacccgaacctcg	Protospacer
  ** ** ******************   ** 

69. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to MN234161 (Gordonia phage Toast, complete genome) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
actccgcgagcggatgatcgacccgaacctcg	Protospacer
  ** ** ******************   ** 

70. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
ctgcagcccgcggatgatcgacgcgatgtcgg	Protospacer
*  ***** ************* ***** .  

71. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
tgtcagccagcggatcatcgaccagatcgata	Protospacer
..************* ******* *** * . 

72. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to MK801721 (Gordonia phage William, complete genome) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
actccgcgagcggatgatcgacccgaacctcg	Protospacer
  ** ** ******************   ** 

73. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to MK814757 (Gordonia phage Fairfaxidum, complete genome) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
actccgcgagcggatgatcgacccgaacctcg	Protospacer
  ** ** ******************   ** 

74. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to MN234161 (Gordonia phage Toast, complete genome) position: , mismatch: 8, identity: 0.75

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
actccgcgagcggatgatcgacccgaacctcg	Protospacer
  ** ** ******************   ** 

75. spacer 11.13|6222544|35|NZ_CP016353|CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.771

catcagccagcggatgatcgacccgatgg---tctgtg	CRISPR spacer
tgtcagccagcggatcatcgaccagatcgatatct---	Protospacer
..************* ******* *** *   ***   

76. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 9, identity: 0.727

tcgactgcgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
tcgacggcgaaggcgacgaacgcgtcatcggga	Protospacer
***** ************* ****  . **  .

77. spacer 4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 9, identity: 0.727

ctggagaaggacccggcgcaggccgagcgcttc	CRISPR spacer
gtggagaaggccgcggcgcaggccgtggaaatt	Protospacer
 ********* * ************ * .  *.

78. spacer 4.3|2175278|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.727

ctggagaaggacccggcgcaggccgagcgcttc	CRISPR spacer
gccgacgctgatccggcgcacgccgagcgcttc	Protospacer
 . ** .  **.******** ************

79. spacer 4.7|2175522|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.727

ggttggatgtgcgtgaggtcgcggcgtgacgcg	CRISPR spacer
cgttggacgtgcgtgaggtagcggccatctgct	Protospacer
 ******.*********** *****    .** 

80. spacer 5.1|2185421|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP042264 (Litoreibacter sp. LN3S51 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

ctgctcgtcgtcgaccaggcgaagtacttcaa	CRISPR spacer
gagcttgtcgtcgacaaggcgaagtatcagga	Protospacer
  ***.********* **********..  .*

81. spacer 5.1|2185421|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctgctcgtcgtcgaccaggcgaagtacttcaa	CRISPR spacer
ctgctcttcgtcgacgaggcgaacgccgtggt	Protospacer
****** ******** *******   * * . 

82. spacer 5.1|2185421|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP018784 (Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence) position: , mismatch: 9, identity: 0.719

ctgctcgtcgtcgaccaggcgaagtacttcaa	CRISPR spacer
aagttcgtcatcgacccggcgaagtaccggca	Protospacer
  *.*****.****** **********.   *

83. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP014514 (Frondihabitans sp. PAMC 28766 strain SR6 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
gatgaggacaccggcgcgttgatctcccacgc	Protospacer
   ****.******************    .*

84. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP014514 (Frondihabitans sp. PAMC 28766 strain SR6 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
gatgaggacaccggcgcgttgatctcccacgc	Protospacer
   ****.******************    .*

85. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP014516 (Frondihabitans sp. PAMC 28766 strain SR6 plasmid 3, complete sequence) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
gatgaggacaccggcgcgttgatctcccacgc	Protospacer
   ****.******************    .*

86. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
gcacgttccaccggcgtgttgatcacggcaac	Protospacer
 *. .   ********.******* *******

87. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
gcacgttccaccggcgtgttgatcacggcaac	Protospacer
 *. .   ********.******* *******

88. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to MT778840 (Rhizobium phage P11VFA, complete genome) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
cggcagggcagcggcgcgttgatctgggagca	Protospacer
. * ****** ************** ** .  

89. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to KF614509 (Rhizobium phage vB_RleS_L338C, complete genome) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
cggcagggcagcggcgcgttgatctgggagca	Protospacer
. * ****** ************** ** .  

90. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to MT152150 (Pseudomonas phage 8P, complete genome) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
ggcggcaccaccggggcgctgatctcggcaac	Protospacer
   *. . ****** ***.*************

91. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
gcgcagcgcaccggcgcgttgatcgagcgggc	Protospacer
 ** ** *****************  *  ..*

92. spacer 5.6|2185726|32|NZ_CP016353|CRISPRCasFinder matches to JX306041 (Stenotrophomonas phage IME13, complete genome) position: , mismatch: 9, identity: 0.719

tacatcaagggaatcaacacctggaagaacca	CRISPR spacer
agcttcaagggaatcaacagctcgaagtgctc	Protospacer
 .* *************** ** **** .*. 

93. spacer 5.7|2185787|32|NZ_CP016353|CRISPRCasFinder matches to MK095606 (Pantoea phage vB_PagS_AAS23, complete genome) position: , mismatch: 9, identity: 0.719

tacgaaac----ccaacagaaactgctgttcctgtg	CRISPR spacer
----aggcattaccaaaagaacctgctgttcctgtt	Protospacer
    *..*    **** **** ************* 

94. spacer 5.9|2185909|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP014310 (Burkholderia sp. PAMC 26561 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

ccgctgccgaaggtgctcgtgtactgggagta	CRISPR spacer
acgctgccgaaggtgatcgtgtacaccgtcac	Protospacer
 ************** ********   *    

95. spacer 5.10|2185970|32|NZ_CP016353|CRISPRCasFinder matches to NC_006907 (Leptospirillum ferrooxidans plasmid p49879.1, complete sequence) position: , mismatch: 9, identity: 0.719

gtgtcccgaaccactaccgcgcgtcctatgtg	CRISPR spacer
ccttcccgaaacactcccgcgcgtccttcctc	Protospacer
 . ******* **** *********** . * 

96. spacer 5.10|2185970|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 9, identity: 0.719

gtgtcccgaaccactaccgcgcgtcctatgtg	CRISPR spacer
gccgcccgaaccaccaccgcgcgtcgtactcc	Protospacer
*.  **********.********** **. . 

97. spacer 5.11|2186031|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

gatcctggggccgaccggctcgccttgctcca	CRISPR spacer
gatcctggggccgatcggctggctgatgttcg	Protospacer
**************.***** **.    *.*.

98. spacer 5.19|2185848|33|NZ_CP016353|CRT matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 9, identity: 0.727

gatcgtcgatggtgtccggtcggtcgtagagac	CRISPR spacer
cgacgaagatgttgtcgggtcggtcgtagagtt	Protospacer
 . **  **** **** ************** .

99. spacer 5.28|2185855|33|NZ_CP016353|PILER-CR matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 9, identity: 0.727

gatcgtcgatggtgtccggtcggtcgtagagac	CRISPR spacer
cgacgaagatgttgtcgggtcggtcgtagagtt	Protospacer
 . **  **** **** ************** .

100. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to MK801723 (Gordonia phage Coeur, complete genome) position: , mismatch: 9, identity: 0.735

gctcgtcggatgtcggccagctcggcgcgagcgg	CRISPR spacer
ttgcgtcggatgccggccagctcggcgctgaatg	Protospacer
 . *********.*************** ..  *

101. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_004963 (Mycobacterium celatum plasmid pCLP, complete sequence) position: , mismatch: 9, identity: 0.735

gctcgtcg-gatgtcggccagctcggcgcgagcgg	CRISPR spacer
-tccaccgcgaggtcggccagctcggcgcgggcta	Protospacer
 ..*..** ** ******************.** .

102. spacer 6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.727

gctggctgacggtcgatgaggcgacgatcaacg	CRISPR spacer
tcagctcgaccgtcgacgaggcgacgatcaaga	Protospacer
 * * ..*** *****.************** .

103. spacer 6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.727

gctggctgacggtcgatgaggcgacgatcaacg	CRISPR spacer
ggatgctgacggtcgatgggccgacgatgattt	Protospacer
*   **************.* ******* * . 

104. spacer 6.8|2666164|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_015146 (Pseudarthrobacter phenanthrenivorans Sphe3 plasmid pASPHE301, complete sequence) position: , mismatch: 9, identity: 0.727

tgccggacaccagcaccacaccggtaccgccgg	CRISPR spacer
ggcaccacaccagtaccataccggtaccgcacc	Protospacer
 **   *******.****.***********   

105. spacer 6.15|2666047|34|NZ_CP016353|PILER-CR matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

gctggctgacggtcgatgaggcgacgatcaacgg	CRISPR spacer
ggatgctgacggtcgatgggccgacgatgatttg	Protospacer
*   **************.* ******* * . *

106. spacer 6.15|2666047|34|NZ_CP016353|PILER-CR matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 9, identity: 0.735

gctggctgacggtcgatgaggcgacgatcaacgg	CRISPR spacer
gctggctgacggtcgaataggcgagcctcgcctt	Protospacer
****************  ******   **. *  

107. spacer 6.17|2666169|34|NZ_CP016353|PILER-CR matches to AP014371 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S42-C166, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.735

tgccggacaccagcaccacaccggtaccgccggg	CRISPR spacer
ttttagacaccagcaccacaccggcaacgctgaa	Protospacer
* ...*******************.* ***.*..

108. spacer 9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594660 (Variovorax sp. PBL-H6 plasmid 2) position: , mismatch: 9, identity: 0.727

ctggtcctgaagctggtccccgagctggccccg	CRISPR spacer
gccgtgtcgatgctggtgcccgagctggccccc	Protospacer
 . ** ..** ****** ************** 

109. spacer 9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594667 (Variovorax sp. SRS16 plasmid 2) position: , mismatch: 9, identity: 0.727

ctggtcctgaagctggtccccgagctggccccg	CRISPR spacer
gccgtgtcgatgctggtgcccgagctggccccc	Protospacer
 . ** ..** ****** ************** 

110. spacer 9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594690 (Variovorax sp. WDL1 plasmid 2) position: , mismatch: 9, identity: 0.727

ctggtcctgaagctggtccccgagctggccccg	CRISPR spacer
gccgtgtcgatgctggtgcccgagctggccccc	Protospacer
 . ** ..** ****** ************** 

111. spacer 9.1|4403470|33|NZ_CP016353|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594672 (Variovorax sp. PBL-E5 plasmid 2) position: , mismatch: 9, identity: 0.727

ctggtcctgaagctggtccccgagctggccccg	CRISPR spacer
gccgtgtcgatgctggtgcccgagctggccccc	Protospacer
 . ** ..** ****** ************** 

112. spacer 11.2|6222421|33|NZ_CP016353|PILER-CR,CRISPRCasFinder matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

cactgagactcaatgttgacgggaccggcctgg	CRISPR spacer
agcggccgatcaatggtgacgggaccggcatgg	Protospacer
 .* *  . ****** ************* ***

113. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 9, identity: 0.719

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
catcatcgagcggatgatcgaccttgccgccc	Protospacer
***** * ***************. .. *.*.

114. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 9, identity: 0.719

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
catcatcgagcggatgatcgaccttgccgccc	Protospacer
***** * ***************. .. *.*.

115. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 9, identity: 0.719

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
catcatcgagcggatgatcgaccttgccgccc	Protospacer
***** * ***************. .. *.*.

116. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 9, identity: 0.719

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
catcatcgagcggatgatcgaccttgccgccc	Protospacer
***** * ***************. .. *.*.

117. spacer 11.9|6222665|33|NZ_CP016353|CRISPRCasFinder matches to NC_019540 (Salinivibrio phage CW02, complete genome) position: , mismatch: 9, identity: 0.727

ggttctgatgatgtccttgacagcaaggcacag	CRISPR spacer
gtggatgattatgtccttgacagcatggctaaa	Protospacer
*    **** *************** ***  *.

118. spacer 12.3|6488268|32|NZ_CP016353|CRISPRCasFinder matches to NC_009806 (Kineococcus radiotolerans SRS30216 = ATCC BAA-149 plasmid pKRAD01, complete sequence) position: , mismatch: 9, identity: 0.719

ccccggcgacctcttcagctccgtacgaatag	CRISPR spacer
ccccggcgaccccgtcagctccggcagaccca	Protospacer
***********.* *********   ** . .

119. spacer 2.2|1413259|33|NZ_CP016353|CRISPRCasFinder matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 10, identity: 0.697

tcgactgcgaaggcgacgaccgcgaaggcgtcg	CRISPR spacer
cacgccgcgaaggcgaggaccgcgatggcgatc	Protospacer
.  .*.********** ******** **** . 

120. spacer 4.12|2175828|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.697

atgaagatggccgtcctcaaggtcgtctccgag	CRISPR spacer
gaagaattgtccgtcctcaaggtcgtgtccgtc	Protospacer
. ..*. ** **************** ****  

121. spacer 4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to MN694527 (Marine virus AFVG_250M568, complete genome) position: , mismatch: 10, identity: 0.697

gctggatcaacacagcggtgttgatggtcgtgg	CRISPR spacer
taacgttcaagacaacggtgttgatggtcgaca	Protospacer
    * **** ***.***************  .

122. spacer 4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to MN694027 (Marine virus AFVG_250M455, complete genome) position: , mismatch: 10, identity: 0.697

gctggatcaacacagcggtgttgatggtcgtgg	CRISPR spacer
taatgttcaagacaacggtgttgatggtcgaca	Protospacer
    * **** ***.***************  .

123. spacer 4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to MN694088 (Marine virus AFVG_250M454, complete genome) position: , mismatch: 10, identity: 0.697

gctggatcaacacagcggtgttgatggtcgtgg	CRISPR spacer
taatgttcaagacaacggtgttgatggtcgaca	Protospacer
    * **** ***.***************  .

124. spacer 4.14|2175950|33|NZ_CP016353|CRISPRCasFinder,CRT,PILER-CR matches to MN694007 (Marine virus AFVG_250M456, complete genome) position: , mismatch: 10, identity: 0.697

gctggatcaacacagcggtgttgatggtcgtgg	CRISPR spacer
taatgttcaagacaacggtgttgatggtcgaca	Protospacer
    * **** ***.***************  .

125. spacer 5.1|2185421|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP007510 (Pseudomonas stutzeri strain 19SMN4 plasmid pLIB119, complete plasmid) position: , mismatch: 10, identity: 0.688

ctgctcgtcgtcgaccaggcgaagtacttcaa	CRISPR spacer
tggctcgtcttcgaccaggcgcagtgcgcgct	Protospacer
. ******* *********** ***.* .   

126. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to MT498059 (Gordonia phage Doggs, complete genome) position: , mismatch: 10, identity: 0.688

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
agcggtacaacgggcgcgctgatctcggcaac	Protospacer
   *. .  ** ******.*************

127. spacer 5.9|2185909|32|NZ_CP016353|CRISPRCasFinder matches to MN694142 (Marine virus AFVG_250M416, complete genome) position: , mismatch: 10, identity: 0.688

ccgctgc-cgaaggtgctcgtgtactgggagta	CRISPR spacer
-aattatacgaaggtgctcctgcactgggaggt	Protospacer
  ..*.. *********** **.********  

128. spacer 5.10|2185970|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.688

gtgtcccgaaccactaccgcgcgtcctatgtg	CRISPR spacer
gccggccgaaccaccaccgcgcgtcatactcc	Protospacer
*.   *********.********** **. . 

129. spacer 5.10|2185970|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.688

gtgtcccgaaccactaccgcgcgtcctatgtg	CRISPR spacer
gccggccgaaccaccaccgcgcgtcatactcc	Protospacer
*.   *********.********** **. . 

130. spacer 5.10|2185970|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 10, identity: 0.688

gtgtcccgaaccactaccgcgcgtcctatgtg	CRISPR spacer
gccggccgaaccaccaccgcgcgtcatactcc	Protospacer
*.   *********.********** **. . 

131. spacer 5.11|2186031|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP013635 (Rhizobium sp. N324 plasmid pRspN324e, complete sequence) position: , mismatch: 10, identity: 0.688

gatcctggggccgaccggctcgccttgctcca	CRISPR spacer
aggcacttcgccgaccggcacgccttcctcca	Protospacer
.. * .   ********** ****** *****

132. spacer 5.12|2185421|33|NZ_CP016353|CRT matches to NZ_CP042264 (Litoreibacter sp. LN3S51 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.697

ctgctcgtcgtcgaccaggcgaagtacttcaac	CRISPR spacer
gagcttgtcgtcgacaaggcgaagtatcaggag	Protospacer
  ***.********* **********..  .* 

133. spacer 5.15|2185604|33|NZ_CP016353|CRT matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 10, identity: 0.697

tcggagggcaccggcgcgttgatctcggcaacg	CRISPR spacer
gcacgttccaccggcgtgttgatcacggcaaca	Protospacer
 *. .   ********.******* *******.

134. spacer 5.15|2185604|33|NZ_CP016353|CRT matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 10, identity: 0.697

tcggagggcaccggcgcgttgatctcggcaacg	CRISPR spacer
gcacgttccaccggcgtgttgatcacggcaaca	Protospacer
 *. .   ********.******* *******.

135. spacer 5.15|2185604|33|NZ_CP016353|CRT matches to MT152150 (Pseudomonas phage 8P, complete genome) position: , mismatch: 10, identity: 0.697

tcggagggcaccggcgcgttgatctcggcaacg	CRISPR spacer
ggcggcaccaccggggcgctgatctcggcaacc	Protospacer
   *. . ****** ***.************* 

136. spacer 5.21|2185970|33|NZ_CP016353|CRT matches to NC_006907 (Leptospirillum ferrooxidans plasmid p49879.1, complete sequence) position: , mismatch: 10, identity: 0.697

gtgtcccgaaccactaccgcgcgtcctatgtgg	CRISPR spacer
ccttcccgaaacactcccgcgcgtccttcctct	Protospacer
 . ******* **** *********** . *  

137. spacer 5.21|2185970|33|NZ_CP016353|CRT matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 10, identity: 0.697

gtgtcccgaaccactaccgcgcgtcctatgtgg	CRISPR spacer
gccgcccgaaccaccaccgcgcgtcgtactccc	Protospacer
*.  **********.********** **. .  

138. spacer 5.24|2185611|33|NZ_CP016353|PILER-CR matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 10, identity: 0.697

tcggagggcaccggcgcgttgatctcggcaacg	CRISPR spacer
gcacgttccaccggcgtgttgatcacggcaaca	Protospacer
 *. .   ********.******* *******.

139. spacer 5.24|2185611|33|NZ_CP016353|PILER-CR matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 10, identity: 0.697

tcggagggcaccggcgcgttgatctcggcaacg	CRISPR spacer
gcacgttccaccggcgtgttgatcacggcaaca	Protospacer
 *. .   ********.******* *******.

140. spacer 5.24|2185611|33|NZ_CP016353|PILER-CR matches to MT152150 (Pseudomonas phage 8P, complete genome) position: , mismatch: 10, identity: 0.697

tcggagggcaccggcgcgttgatctcggcaacg	CRISPR spacer
ggcggcaccaccggggcgctgatctcggcaacc	Protospacer
   *. . ****** ***.************* 

141. spacer 5.30|2185977|33|NZ_CP016353|PILER-CR matches to NC_006907 (Leptospirillum ferrooxidans plasmid p49879.1, complete sequence) position: , mismatch: 10, identity: 0.697

gtgtcccgaaccactaccgcgcgtcctatgtgg	CRISPR spacer
ccttcccgaaacactcccgcgcgtccttcctct	Protospacer
 . ******* **** *********** . *  

142. spacer 5.30|2185977|33|NZ_CP016353|PILER-CR matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 10, identity: 0.697

gtgtcccgaaccactaccgcgcgtcctatgtgg	CRISPR spacer
gccgcccgaaccaccaccgcgcgtcgtactccc	Protospacer
*.  **********.********** **. .  

143. spacer 6.6|2666042|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 10, identity: 0.697

gctggctgacggtcgatgaggcgacgatcaacg	CRISPR spacer
aacggctgacggcggatgaggcgacgaagctgg	Protospacer
. .*********. *************     *

144. spacer 6.15|2666047|34|NZ_CP016353|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.706

gctggctgacggtcgatgaggcgacgatcaacgg	CRISPR spacer
tcagctcgaccgtcgacgaggcgacgatcaagac	Protospacer
 * * ..*** *****.************** . 

145. spacer 6.17|2666169|34|NZ_CP016353|PILER-CR matches to NC_015146 (Pseudarthrobacter phenanthrenivorans Sphe3 plasmid pASPHE301, complete sequence) position: , mismatch: 10, identity: 0.706

tgccggacaccagcaccacaccggtaccgccggg	CRISPR spacer
ggcaccacaccagtaccataccggtaccgcacca	Protospacer
 **   *******.****.***********   .

146. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to NZ_CP019641 (Planococcus sp. Y42 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
atccgtccagcggctgatcgccccgatggaga	Protospacer
  .*. ******* ****** ********   

147. spacer 11.4|6222549|32|NZ_CP016353|PILER-CR matches to NZ_LR594668 (Variovorax sp. SRS16 plasmid 3) position: , mismatch: 10, identity: 0.688

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
gcgcgtggagcggatgctcgaccagatggtcg	Protospacer
   *.   ******** ****** ******* 

148. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP019641 (Planococcus sp. Y42 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
atccgtccagcggctgatcgccccgatggaga	Protospacer
  .*. ******* ****** ********   

149. spacer 11.7|6222544|32|NZ_CP016353|CRISPRCasFinder matches to NZ_LR594668 (Variovorax sp. SRS16 plasmid 3) position: , mismatch: 10, identity: 0.688

catcagccagcggatgatcgacccgatggtct	CRISPR spacer
gcgcgtggagcggatgctcgaccagatggtcg	Protospacer
   *.   ******** ****** ******* 

150. spacer 11.11|6222421|36|NZ_CP016353|CRT matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.722

cactgagactcaatgttgacgggaccggcctgggtg	CRISPR spacer
agcggccgatcaatggtgacgggaccggcatgggtc	Protospacer
 .* *  . ****** ************* ***** 

151. spacer 11.13|6222544|35|NZ_CP016353|CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 10, identity: 0.714

catcagccagcggatgatcgacccgatggtctgtg	CRISPR spacer
tgtcagccagcggatcatcgaccagatcgacatct	Protospacer
..************* ******* *** * *  . 

152. spacer 12.2|6488207|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cgcagcaacacggcgaatccgtcgtcggtggt	CRISPR spacer
ggcagcagcacggcgaattcgtcgccacccag	Protospacer
 ******.**********.*****.*. . . 

153. spacer 12.2|6488207|32|NZ_CP016353|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.688

cgcagcaacacggcgaatccgtcgtcggtggt	CRISPR spacer
ggcagcagcacggcgaattcgtcgccacccag	Protospacer
 ******.**********.*****.*. . . 

154. spacer 12.2|6488207|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cgcagcaacacggcgaatccgtcgtcggtggt	CRISPR spacer
ggcagcagcacggcgaattcgtcgccacccag	Protospacer
 ******.**********.*****.*. . . 

155. spacer 12.2|6488207|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cgcagcaacacggcgaatccgtcgtcggtggt	CRISPR spacer
ggcagcagcacggcgaattcgtcgccacccag	Protospacer
 ******.**********.*****.*. . . 

156. spacer 12.2|6488207|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 10, identity: 0.688

cgcagcaacacggcgaatccgtcgtcggtggt	CRISPR spacer
gctttcatcacggcgaatacgtcgtcggagaa	Protospacer
  .  ** ********** ********* *. 

157. spacer 5.4|2185604|32|NZ_CP016353|CRISPRCasFinder matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 11, identity: 0.656

tcggagggcaccggcgcgttgatctcggcaac	CRISPR spacer
agcagcggaaccggcgcgctgatctcggcgct	Protospacer
   .. ** *********.**********. .

158. spacer 6.1|2665734|33|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_022358 (Sulfuricella denitrificans skB26 plasmid pSCD, complete sequence) position: , mismatch: 11, identity: 0.667

cgagatacgccgtggccggtgtggttgctgtgg	CRISPR spacer
tttctggtgccgtagacggtgtggttgctgtga	Protospacer
.     ..*****.* ****************.

159. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_019018 (Mycobacterium marinum DL240490 plasmid pMUM003, complete sequence) position: , mismatch: 11, identity: 0.676

gctcgtcggatgtcggccagctcggcgcgagcgg	CRISPR spacer
acagcggtgatgtcgcccagctcgtcgcgagcca	Protospacer
.*      ******* ******** ******* .

160. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_011355 (Mycobacterium liflandii 128FXT plasmid pMUM002, complete sequence) position: , mismatch: 11, identity: 0.676

gctcgtcggatgtcggccagctcggcgcgagcgg	CRISPR spacer
acagcggtgatgtcgcccagctcgtcgcgagcca	Protospacer
.*      ******* ******** ******* .

161. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NZ_AP017625 (Mycobacterium ulcerans subsp. shinshuense strain ATCC 33728 plasmid pShTP, complete sequence) position: , mismatch: 11, identity: 0.676

gctcgtcggatgtcggccagctcggcgcgagcgg	CRISPR spacer
acagcggtgatgtcgcccagctcgtcgcgagcca	Protospacer
.*      ******* ******** ******* .

162. spacer 6.2|2665795|34|NZ_CP016353|CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 11, identity: 0.676

gctcgtcggatgtcggccagctcggcgcgagcgg	CRISPR spacer
agcaactgcgtgtcggccggcgcggcgcgagcgg	Protospacer
. . ...* .********.** ************

163. spacer 6.15|2666047|34|NZ_CP016353|PILER-CR matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 11, identity: 0.676

gctggctgacggtcgatgaggcgacgatcaacgg	CRISPR spacer
aacggctgacggcggatgaggcgacgaagctgga	Protospacer
. .*********. *************     *.