CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020028	Paenibacillus kribbensis strain AM49 chromosome, complete genome	4 crisprs	WYL,DinG,csa3,cas3,cas2,cas1,cas4,cas7,cas8c,cas5,DEDDh,cas14j	0	7	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020028_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020028_1

335317-336957

Orphan

I-C

Consensus_repeat	Method
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CRT

24 spacers

The CRISPR arrays of NZ_CP020028_1

>merge|NZ_CP020028|1|335317-336957|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATACGAGTGCGTGGATTGAAATCGTCTGGCTGTAGAGGTCAGCGGACAGCGTACCTTGGTCGCACTCTATACGAGTGCGTGGATTGAAATTTAGATTAATCTAAGAAATGCAAATTTCAATACACGTCGCACTCTATACGAGTGCGTGGATTGAAATTGCACATATCCATTATCGTATTCGGTCTTATTTTAGTCGCACTCTATACGAGTGCGTGGATTGAAATGCGTTGCATTTTACTCAGATTCTGGCGTTTTGATTGGCGTCGCACTCTATACGAGTGCGTGGATTGAAATATCTTTCCGAAGAAAAAGGGAAATATTTCGCTATGGTAGTCGCACTCTATACGAGTGCGTGGATTGAAATTGTTTCACCAAGAACCTGGAACCACCGCGAAAATTGTCGCACTCTATACGAGTGCGTGGATTGAAATATACGGTACGTTATATTAGATCGAATCCGGGTTAAAGTCGCACTCTATACGAGTGCGTGGATTGAAATAATACGGACGCTTTCTATGTACAAGAGCCTGGCGGTCGCACTCTATACGAGTGCGTGGATTGAAATGATTAATAGTCGAGTCAGGGGCCTTTTTGCGTTGTCGTCGCACTCTATACGAGTGCGTGGATTGAAATTCTTACTCCTAAAATGGTTGATTGGATGGCTAAGTCGCACTCTATACGAGTGCGTGGATTGAAATTGTATACGAAAAAAATGGCCATTTTTTTTATGTAGTCGCACTCTATACGAGTGCGTGGATTGAAATTCCCCCGTTGCTTGTTCGCTATCTTATGCCCCTATGTCGCACTCTATACGAGTGCGTGGATTGAAATCTGTATGAAAAAAGGATGATATTATTGTGTTCAAGTCGCACTCTATACGAGTGCGTGGATTGAAATCTGAAAATGAGGTGCCTATGACCATCTTTTGCAGTCGCACTCTATACGAGTGCGTGGATTGAAATAAGTGAAAAATGTCAAGTGGAATAGCGTAGAACGTCGCACTCTATACGAGTGCGTGGATTGAAATATATCTGTTATCCGTAATTCCTTTCGTAGAGACAAGGGTCGCACTCTATACGAGTGCGTGGATTGAAATTAGGTATCGTAAAGGGTGATCCAATCGGCTACTACGGGTCGCACTCTATACGAGTGCGTGGATTGAAATCTGAAAATGAGGTGCCTATGACCATCTTTTGCAGGTCGCACTCTATACGAGTGCGTGGATTGAAATATGTGCTGGACGCTGTGGGCAGCTGGCATAAGTTTGGTCGCACTCTATACGAGTGCGTGGATTGAAATATATCACCACTCATTTCCGAACATTATTTCAACGTCGCACTCTATACGAGTGCGTGGATTGAAATGCTGCCTCTGAATTTACTTATACGGTTCCGCTGCCAGTCGCACTCTATACGAGTGCGTGGATTGAAATTTCATCACCTGGGCTTATATGTTGGGTGGCGCTAGTCGCACTCTATATGAGTGCGTGGATTGAAATAACGGAGTTAAGTAGATAACCATCAACTTTTTTAGTCGCACTCTATATGAGTGCGTGGATTGAAATTCCGTCTCGCCGGATGAGTTTTTTGCATCAGCCAAGTCGCACTCTATACGAGTGCGTGGATTGAAAT

>NZ_CP020028|1|1|335317-336957|PILER-CR
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CGTCTGGCTGTAGAGGTCAGCGGACAGCGTACCTTG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TTAGATTAATCTAAGAAATGCAAATTTCAATACAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGCACATATCCATTATCGTATTCGGTCTTATTTTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GCGTTGCATTTTACTCAGATTCTGGCGTTTTGATTGGC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATCTTTCCGAAGAAAAAGGGAAATATTTCGCTATGGTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGTTTCACCAAGAACCTGGAACCACCGCGAAAATT
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATACGGTACGTTATATTAGATCGAATCCGGGTTAAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	AATACGGACGCTTTCTATGTACAAGAGCCTGGCG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GATTAATAGTCGAGTCAGGGGCCTTTTTGCGTTGTC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TCTTACTCCTAAAATGGTTGATTGGATGGCTAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGTATACGAAAAAAATGGCCATTTTTTTTATGTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TCCCCCGTTGCTTGTTCGCTATCTTATGCCCCTAT
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGTATGAAAAAAGGATGATATTATTGTGTTCAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGAAAATGAGGTGCCTATGACCATCTTTTGCA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	AAGTGAAAAATGTCAAGTGGAATAGCGTAGAAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATATCTGTTATCCGTAATTCCTTTCGTAGAGACAAGG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TAGGTATCGTAAAGGGTGATCCAATCGGCTACTACGG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGAAAATGAGGTGCCTATGACCATCTTTTGCAG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATGTGCTGGACGCTGTGGGCAGCTGGCATAAGTTTG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATATCACCACTCATTTCCGAACATTATTTCAAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GCTGCCTCTGAATTTACTTATACGGTTCCGCTGCCA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TTCATCACCTGGGCTTATATGTTGGGTGGCGCTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACGGAGTTAAGTAGATAACCATCAACTTTTTTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCCGTCTCGCCGGATGAGTTTTTTGCATCAGCCAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT

>NZ_CP020028|1|1|335317-336957|CRISPRCasFinder
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CGTCTGGCTGTAGAGGTCAGCGGACAGCGTACCTTG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TTAGATTAATCTAAGAAATGCAAATTTCAATACAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGCACATATCCATTATCGTATTCGGTCTTATTTTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GCGTTGCATTTTACTCAGATTCTGGCGTTTTGATTGGC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATCTTTCCGAAGAAAAAGGGAAATATTTCGCTATGGTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGTTTCACCAAGAACCTGGAACCACCGCGAAAATT
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATACGGTACGTTATATTAGATCGAATCCGGGTTAAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	AATACGGACGCTTTCTATGTACAAGAGCCTGGCG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GATTAATAGTCGAGTCAGGGGCCTTTTTGCGTTGTC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TCTTACTCCTAAAATGGTTGATTGGATGGCTAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGTATACGAAAAAAATGGCCATTTTTTTTATGTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TCCCCCGTTGCTTGTTCGCTATCTTATGCCCCTAT
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGTATGAAAAAAGGATGATATTATTGTGTTCAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGAAAATGAGGTGCCTATGACCATCTTTTGCA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	AAGTGAAAAATGTCAAGTGGAATAGCGTAGAAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATATCTGTTATCCGTAATTCCTTTCGTAGAGACAAGG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TAGGTATCGTAAAGGGTGATCCAATCGGCTACTACGG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGAAAATGAGGTGCCTATGACCATCTTTTGCAG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATGTGCTGGACGCTGTGGGCAGCTGGCATAAGTTTG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATATCACCACTCATTTCCGAACATTATTTCAAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GCTGCCTCTGAATTTACTTATACGGTTCCGCTGCCA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TTCATCACCTGGGCTTATATGTTGGGTGGCGCTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACGGAGTTAAGTAGATAACCATCAACTTTTTTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCCGTCTCGCCGGATGAGTTTTTTGCATCAGCCAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT

>NZ_CP020028|1|1|335317-336957|CRT
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CGTCTGGCTGTAGAGGTCAGCGGACAGCGTACCTTG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TTAGATTAATCTAAGAAATGCAAATTTCAATACAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGCACATATCCATTATCGTATTCGGTCTTATTTTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GCGTTGCATTTTACTCAGATTCTGGCGTTTTGATTGGC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATCTTTCCGAAGAAAAAGGGAAATATTTCGCTATGGTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGTTTCACCAAGAACCTGGAACCACCGCGAAAATT
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATACGGTACGTTATATTAGATCGAATCCGGGTTAAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	AATACGGACGCTTTCTATGTACAAGAGCCTGGCG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GATTAATAGTCGAGTCAGGGGCCTTTTTGCGTTGTC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TCTTACTCCTAAAATGGTTGATTGGATGGCTAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TGTATACGAAAAAAATGGCCATTTTTTTTATGTA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TCCCCCGTTGCTTGTTCGCTATCTTATGCCCCTAT
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGTATGAAAAAAGGATGATATTATTGTGTTCAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGAAAATGAGGTGCCTATGACCATCTTTTGCA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	AAGTGAAAAATGTCAAGTGGAATAGCGTAGAAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATATCTGTTATCCGTAATTCCTTTCGTAGAGACAAGG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TAGGTATCGTAAAGGGTGATCCAATCGGCTACTACGG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	CTGAAAATGAGGTGCCTATGACCATCTTTTGCAG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATGTGCTGGACGCTGTGGGCAGCTGGCATAAGTTTG
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	ATATCACCACTCATTTCCGAACATTATTTCAAC
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	GCTGCCTCTGAATTTACTTATACGGTTCCGCTGCCA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT	TTCATCACCTGGGCTTATATGTTGGGTGGCGCTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACGGAGTTAAGTAGATAACCATCAACTTTTTTA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCCGTCTCGCCGGATGAGTTTTTTGCATCAGCCAA
GTCGCACTCTATACGAGTGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020028.1\|WP_094153519.1\|346026_346878_+\|uroporphyrinogen-III-synthase	unknown	unknown	gnl\|CDD\|235647
NZ_CP020028.1\|WP_167383737.1\|331940_332921_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|307170
NZ_CP020028.1\|WP_094153513.1\|337534_337831_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094153518.1\|344752_345925_+\|endospore-germination-permease	unknown	unknown	gnl\|CDD\|273333
NZ_CP020028.1\|WP_068497500.1\|344489_344714_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094153509.1\|329298_329706_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP020028.1\|WP_007432866.1\|326544_326940_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NZ_CP020028.1\|WP_007432857.1\|334758_335094_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094153508.1\|328318_329179_+\|M56-family-metallopeptidase	unknown	unknown	gnl\|CDD\|320685
NZ_CP020028.1\|WP_007432858.1\|334028_334742_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NZ_CP020028.1\|WP_094153510.1\|329858_331844_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP020028.1\|WP_094153515.1\|340584_341235_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094153507.1\|326915_327755_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP020028.1\|WP_167383738.1\|341231_341402_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094153514.1\|338300_338798_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094156920.1\|339828_340374_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094153516.1\|341651_343277_+\|spore-germination-protein	unknown	unknown	gnl\|CDD\|377020
NZ_CP020028.1\|WP_007432864.1\|327901_328315_+\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NZ_CP020028.1\|WP_094153512.1\|333100_333958_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176133
NZ_CP020028.1\|WP_094153517.1\|343276_344497_+\|Ger(x)C-family-spore-germination-protein	unknown	unknown	gnl\|CDD\|274338

Protein	Function_ID	Function_description	E-value
NZ_CP020028.1\|WP_094153519.1\|346026_346878_+\|uroporphyrinogen-III-synthase	gnl\|CDD\|235647	PRK05928, hemD, uroporphyrinogen-III synthase; Reviewed.	1.50444e-57
NZ_CP020028.1\|WP_167383737.1\|331940_332921_-\|EamA-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	5.37108e-10
NZ_CP020028.1\|WP_094153518.1\|344752_345925_+\|endospore-germination-permease	gnl\|CDD\|273333	TIGR00912, Spore_germination_protein_A2, spore germination protein (amino acid permease). This model describes spore germination protein GerKB and paralogs from Bacillus subtilis, Clostridium tetani, and other known or predicted endospore-forming members of the Firmicutes (low-GC Gram positive bacteria). Members show some similarity to amino acid permeases. [Transport and binding proteins, Amino acids, peptides and amines].	2.25246e-31
NZ_CP020028.1\|WP_094153509.1\|329298_329706_+\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	1.16565e-17
NZ_CP020028.1\|WP_007432866.1\|326544_326940_+\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	1.04046e-35
NZ_CP020028.1\|WP_094153508.1\|328318_329179_+\|M56-family-metallopeptidase	gnl\|CDD\|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	5.02967e-48
NZ_CP020028.1\|WP_007432858.1\|334028_334742_+\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	1.52e-58
NZ_CP020028.1\|WP_094153510.1\|329858_331844_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	2.02567e-66
NZ_CP020028.1\|WP_094153507.1\|326915_327755_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.96153e-31
NZ_CP020028.1\|WP_094153516.1\|341651_343277_+\|spore-germination-protein	gnl\|CDD\|377020	pfam03323, GerA, Bacillus/Clostridium GerA spore germination protein.	0
NZ_CP020028.1\|WP_007432864.1\|327901_328315_+\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	1.16309e-26
NZ_CP020028.1\|WP_094153512.1\|333100_333958_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176133	cd08442, PBP2_YofA_SoxR_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold. YofA is a LysR-like transcriptional regulator of cell growth in Bacillus subtillis. YofA controls cell viability and the formation of constrictions during cell division. YofaA positively regulates expression of the cell division gene ftsW, and thus is essential for cell viability during stationary-phase growth of Bacillus substilis. YofA shows significant homology to SoxR from Arthrobacter sp. TE1826. SoxR is a negative regulator for the sarcosine oxidase gene soxA. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine, which is involved in the metabolism of creatine and choline. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.82529e-74
NZ_CP020028.1\|WP_094153517.1\|343276_344497_+\|Ger(x)C-family-spore-germination-protein	gnl\|CDD\|274338	TIGR02887, Spore_germination_protein_B3, germination protein, Ger(x)C family. Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination].	1.02373e-88

>NZ_CP020028.1|WP_007432857.1|334758_335094_+|hypothetical-protein
MAQQETWLIKHAVTGRSFADSRKQVFDCRLETTDGLFCFTLQELPRETAEAIVRYSGELNVFRFVTPEDKSIVKHWYYVTPESVKYNDQTGELTLEADSKIEYHPEEYWGD
>NZ_CP020028.1|WP_007432858.1|334028_334742_+|pirin-family-protein
MFTIYPAASRFSFDKGWLRGSHSFSFAEYQDENNTAFGPMRVCNDDVIAPGRGFGAHPHSDMEIVSIVLYGELRHEDNRGHEAVTRFGGIQRMSAGRGIVHTEHNASQTEDVCLLQLWFSPHTRGLEPSYEATAFNPERLHGQLLPVVAGNRVPGTEGEIAAIHQDLTIYLSKLQAGERLEFTQAEGRRVFLFIIEGSLRVNGQHILQERDSARIEQEPKLLLEAQEPVFYMLIDLP
>NZ_CP020028.1|WP_094153512.1|333100_333958_+|LysR-family-transcriptional-regulator
MDLNDLNIFQTVAAHGSVSKAAAELSYVQSNVTARIKLLEKELQTPLFYRHKRGMILNAEGKRLLQYTKSILSQFEEMKHAFQSTSTPSGVLEIGIVETVVALPSILHAYYSHYPDVELSLKAGVTEHLVQEVAEMRLDGAFVTGPVKHPLIEQFDVFQEKLVLVSQGDDFSVEDITTRPLLLYKKGCGYRERLETWLKMEGIIPKQIMEFGTFETIVGSVAAGIGMTVFPESSISGLRAQGHVHCHALPEPYNEVTTVFIRRKEAYVTSTLQSFIDEIIAQIQA
>NZ_CP020028.1|WP_167383737.1|331940_332921_-|EamA-family-transporter
MNKQIMTGSLLCLIASMSWGAMFPVSHIALQQVNPLYFSFLRYFVVALILIVLLWLKEGRAAFRFEGGGKKLLFFGTMGFTIYNMAVFQGQHWMGAAGTIVASIMEVLMPMISIAMIWTLTRKMPPKYTLISMVIALAGAILVITNGKWTFFTLAGQHLLPLLLIFAGVVGWVVYSMGGSHFAGWSTLRYSTLTCLLGTLVSFVVVTVSSAFHWIAVPDWQDVWSVKYEMSFMILLPGLAALLSWNAGIRKLSPLNGILFINFVPITTLVLMYFQGYAISQFELYGTLLVIFALVLNNMVQRNTLRTSSTSSRIRFRLDRRKLFQR
>NZ_CP020028.1|WP_094153510.1|329858_331844_+|methyl-accepting-chemotaxis-protein
MGKMRKRTTIWTLRNKLVLGFLLILLVPSLSISIATYNSSFNAMEKQLYSSANQGVVTANSVIEYSLSSKIKDVGYLAKGLDGSMIDGRNSPLIQPKLIQYIGLHEDATDIFVGTPDGLMIRGVPKEDEGTYDPRKRDWYIEAMKQPGKVAITPVVINSSGIPVVVVSQTLSDQSGVIGISLNLESVRKLASIKVGQEGYIIILDHTKKFVVHPTIKPGTTLDASFINDMYAAQSGQYTYVYEGQEKYLNYVTNKETGWKIAGTFYQSEISDATAAMRYVTIFVLAASLVLALIAIFLITRSVLVPIRKLQKSAEQISEGDLTGDLETGKTDEVGQLSSHFQTMVDSLRTMIRSVHETTDRVSSSAEELASGADQTTQAIEHVTIAIQEVAVGSERQAQSVKHGSVSMEELAQQAVNVSERMVGVSEQVKSNAESAQAGSKAATRAVQKMHDIDETVNDLGHAMDSLSERSGEIENIIGVISGIAKQTNLLALNASIEAARAGDHGKGFAVVATEVRKLAEESAKSATLISERIEAMQMDMEHALTAMRQARTRVTEGIDSVSTSEQSFAEISQAVELATEHINDITGVTQEMARGAAGVVSIMSDISHISNEAAGNTESISAAAEQQLASIEEIASSSADLSQMAEELRELVGRFRVGEK
>NZ_CP020028.1|WP_094153509.1|329298_329706_+|DoxX-family-protein
MNQTLTNIGLLLVRIFTGVIFIVHGSQKFQGLDGTSGFFQSIGLPGWLAPVVATVELVGGIALVLGIGTRIAGAALTIVMIGVLLTAKKGQPFGSIEFDLLVLFTSLQQALVGGRFLAVDQLFGRKKTENSNVQV
>NZ_CP020028.1|WP_094153508.1|328318_329179_+|M56-family-metallopeptidase
MWKTRSKLLFTAGALISGFALIQMGMYAGQHVFGWKLNFNVFQICRSLLQNYGIGYMVDALSGLVFLTFGIAGCEAVRQCMATRAAFRRLHRMRDLPLTGALGERYRELGADRIWVIDYAKPAAFTMGLWKPRIVLSSALLSVLDKHEEEAVIYHEAHHMKHYDPLKTWMLQICATLLFYLPVLRHITNQYKIAREILADNEAINRAGSPVGIGSALLKLLSMKPAKTRLVNSAACSSFAETSINYRISRILDPQLEPIIPMPWRSIMFSSYVLVMLTLMFALALM
>NZ_CP020028.1|WP_007432864.1|327901_328315_+|BlaI/MecI/CopY-family-transcriptional-regulator
MKRLNFKAGETGLNRFFGPLEAKIMDILWSTSDRSIKEVQTALKGDRDFNFNTVMTVMNRLVEKGILSKSIHGRTSLYRPVLSREEFMDEQSKELSHELVDEFGPLAVNHMIDALEMADPVLIERLEQKIKQWKKDM
>NZ_CP020028.1|WP_094153507.1|326915_327755_+|response-regulator-transcription-factor
MPKQANQITNRFKAAEMPRRVKGNWTTMLSTPSAPVLRTVPSNEPLYCPTTRRLVLISSVPGVVHGLVRTLSDACFDVMVFHRWEPEVQRHLGSDLLIYDLTAADTRSELLDFRNRLAAEHMKDTPVMYVVQDRSAVQAHELLPSEEVLVWPLASNHMVHDIERMIVRHPAASRQAGQASRRTMFKDIWIDRDKMLVYKEEKQLSLTKTEYDLLLKLIDAQGKVISREQMMHDIWETDFVGGSNVVDVHVKSLRKKLDDRPAEPEYIATVRGVGYRLAD
>NZ_CP020028.1|WP_007432866.1|326544_326940_+|transcriptional-repressor
MRTLNLTSQRQAVYDVVREAHDHPTAADVMNRLMERGYNLAYGTVYNSLRYLTDKELIRELKLGEAASRYDGRMDDHQHIICQVCGRVDEVMSEVPDDWTETVAHETGYAIAHAHVVFGGVCKECQSKRIK
>NZ_CP020028.1|WP_094153513.1|337534_337831_+|hypothetical-protein
MLVTRNKISAFILKIAFFSLIIGCIYYYSGSHLSETAKLVEVKDDYLVIQSDTSNGGKIKKLYISSKSVIPSLVVGKEYFFVSDQRYFQRPYIRFVED
>NZ_CP020028.1|WP_094153514.1|338300_338798_+|hypothetical-protein
MSVNALTKKIMLSSATAALLFSVVSPFSASAASTSVTSSTYNESANQPEGVVPPVINGADPSLNGDVTTQGKVSWTIKGIKAALKSQASKIDNVIKTTIDWLPVSDSVKKNLINVVKVDALIKALDVVTDFSGSIEDALSQAMQYLGVAGWLADIIARAIGAIFL
>NZ_CP020028.1|WP_094156920.1|339828_340374_+|hypothetical-protein
MVTDNKNLNPSNNVNNETNKSKSEEKNENQNNEMSEPFLTGTHFEDPNAFIVYDFKMSHDSSDNSVSFRVTYKFGDKPRKYILEGKHPYYFYISVPESLAKYYTLPETIPVKGEELISDDDNLKYQVDIKASLKKGLPKDVINSITNKPQGYSITVFENPDYPAKRIVGVYEFVSTIPPNI
>NZ_CP020028.1|WP_094153515.1|340584_341235_+|hypothetical-protein
MKIFKKVFVPLLASVFLCATVLPSVGNAEQITKSEVNLVQTEVIQTDRGEATVTTNFNDDNHRITTIVENGKTTKIEFFPQDQTLLIDGVKQENFNVKESRSDFSLNAVPSGGTFVGKFDYSYDWVNVGIVFAAGIISTVTKAPVSTILVIIGAGASLNTQSYYTIYQYSYPRKCEAIPYANHTVFYQDASRNKVIGTADSAKFFSSQPYPIGCTP
>NZ_CP020028.1|WP_167383738.1|341231_341402_+|hypothetical-protein
MKKLLKRDASILLGYAVCLGVSYALGYKLNAMMVYTFLAGLITGEIINFALSKREK
>NZ_CP020028.1|WP_094153516.1|341651_343277_+|spore-germination-protein
MKKVHFPKLPRLPWSRRTIRAADRKTQNTNALKGLPEPPWLEQPLRSSLENNLTALRDIFKDCSDIVYRELMISPERKGMLAYVEGTVKSEDLQDHILRPFILGMMLKDPEVNGTLDPLDETRISMSQTKTMDQWKMVSAAILDGNAALFVDGTPRAYIFSAKGGVRRGVEEPQTEAVIRGPREGFTETIRVNTALLRFKLKTSKLKMHSMTMGTETQTSVVLTYIEGIIDPKLVEDVKKRLSDIKIDGVLETGYIEELIEDHPFSPFPEMEYTERPDTVTAQLLEGRFAIFVDGTPFALIGPVTMWQMMQASEDYYERFFISNVVRWIRFLFLILALYLPALYVAVTTYHQDMLPTTLILSIAAARETIPFPALVEALIMEISFEALREAGIRLPKTVGQAVSILGALVIGQASVQAGIVSAPIVIVVSLTGIASFTIPRFNFAITIRLLRFPIMLMAGVFGLFGIIIATTLIATHLTKLTSFGVPYMSGYSPYNHNDQKDIVVRAPWWKMIKRPSWIGNDNNKREKEKMNGSPATEEGW
>NZ_CP020028.1|WP_094153517.1|343276_344497_+|Ger(x)C-family-spore-germination-protein
MKPKGSNAGKIRKAAILSCLLLCSVLLGGCWDRREVNDVAFVMGTGLDKEGDQYRVTMQIALPGQLGSSGSTGGGGGTRGNKSYYLESKIGPSFRGASAEEQRGVSRTLNFSHRRVLLFGEALAREGISKMMDVLARIPQNRLSSLVVITKGASLDVLQADAPIEQYPAEMVRELNFSYMKNPRSIKLLMNSILMEGMDPAVPVMSLVKNGPATIKDKKTNIQVDGLAVFRKDRLTGMIDNHLSRFLLLGMGQAKETEIFIPPPKGSGYLSVHLIENNVQIKPYIRGNDIRMTVQLNCNGNVREDETTFDISNGGNLKWLEQQVAQEIKKELGEAVRLIQQKYHSDVLGLGRAIIMSRPDEWKRIKPQWEQLYPKVEVVIDPIVHIENIGAVTKPFGIKKEQVQNE
>NZ_CP020028.1|WP_068497500.1|344489_344714_+|hypothetical-protein
MNKVFLFPLVLAMLFMYLIDRKSLNSAPAVNRWVSRVLYVISIGIWIYGTSTKSSVYVATWLSRFIDMWLPPTL
>NZ_CP020028.1|WP_094153518.1|344752_345925_+|endospore-germination-permease
MKQFTTRQIVLLSVLMEVSITLVHAPTQAADYAQQHAYWTCAIAAILICFPIWAMLKLKRRFPDQDLLQAIVSSHPMLGRMLLAVYLILFLIIFARDLRIITDLVEVVLLPMTPIVVISLIMLLTLVFMAKGGIRTIVSMTEFTVPALILTLLTMPLFFGHNIDFSAMRPFLHPDIGGVVKGSWRMLGYMADLIILPFILPGRSYNARSAWLGHLIGTVFMIIIVLLEELVIGVPILSRLFYPTYELARQLQLSDFLDRFDLFVGALTVPTLLTKIGVDLYVISLTVKRMFVHIFGGLMVWPMGLLGYVCSFMLFSNIVQIYDFSREWTVVMIAFFVVMPFVLWLLLRPKPEKDSEHHKPSGEKQDSTGQQVSTNQQESQQASRTGKANL
>NZ_CP020028.1|WP_094153519.1|346026_346878_+|uroporphyrinogen-III-synthase
MAQRMAGKRVALAGPRKADEMALLVAKMGGEPVLRPAQGTVFLDDIELRNAVVSWVKQPPDWNIFTTGMGLDALFDMAEDMGVAEQIMELLHSSKIAARGYKTVNELKKRGFTPDVRDEDGSLTGLTRAFAPYDLKGKEVLLQLHGDPAPRLVKWLDEQGAVTRQVLPYKHIPPEEANLQALLADVLNRKVDAVTFTSGPQIRFLCQYARAQNRMDDLLEAFRQDVIAVSVGKVTAQSMLEEGIERIVFPVEERMGAMMVELGKYFEHSASAHGFGLEVVNGH

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Crispr_ID: NZ_CP020028_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020028_2

1792769-1794411

Orphan

I-C

Consensus_repeat	Method
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRT

24 spacers

The CRISPR arrays of NZ_CP020028_2

>merge|NZ_CP020028|2|1792769-1794411|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAATCACACAACTTCGGGGTCGTCCAGGTCTGGCAAGACCAGTCGCACTCTATATGAGTGCGTGGATTGAAATATCTTTTGCTTGCAATGCTTGGTGCCTTTTTTGTAATGTCGCACTCTATATGAGTGCGTGGATTGAAATTTGTCCAGCGAAACAGACGTACCCGAAACGGCTTGCTTGTCGCACTCTATATGAGTGCGTGGATTGAAATAACAAGACTGAGGTCAAGGCCAAATTTGCGGACGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTGTTTGGATTTTTGGCATTGGCATATGCGGGGGAGTCGCACTCTATATGAGTGCGTGGATTGAAATGTTTCATCCAAATCTTTCCACCTCCTCACATAAAGTCGCACTCTATATGAGTGCGTGGATTGAAATTTCCTCCGGTATTCTTTTGCGCCCCAATTATATCCAGTCGCACTCTATATGAGTGCGTGGATTGAAATCACTATAATTCCCAATGACATGGCAAACTGAATGAGTCGCACTCTATATGAGTGCGTGGATTGAAATTTGGTGAACACCGTTACATTCATGAGTGCTTTCAGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTACAAAAGAAAAGGCCACGTTTCACGTAGTTGTGGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTGAAACAGTCATTAATCTTCTGCCGCAAGCTGGCGTCGCACTCTATATGAGTGCGTGGATTGAAATCAATGAATAAAAATAAAGTTTGCCAATACTTGAAGTCGCACTCTATATGAGTGCGTGGATTGAAATTTCGCTGGGGTCATTTCGTTTGTTAGGGGGGTGAGGTCGCACTCTATATGAGTGCGTGGATTGAAATACAAGCGTATGGACGAGCAAAACCACAATCTTTCTGTCGCACTCTATATGAGTGCGTGGATTGAAATACAGCAGCTACAGCAGCAGTTACAAGTCCTTTGGGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTGTATACGGAAAATGATTGGCCAATTTTTTGTGGTCGCACTCTATATGAGTGCGTGGATTGAAATATTTTCGCCCTCCTATCGTAACGCATTACCGCAGTCGCACTCTATATGAGTGCGTGGATTGAAATTGAGGGAAAAAACATCATATGGGACGCGCCACCTGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTAACGGGCCTGTGGATAAGAAATGGACGAGGGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTATTTGACGTGTGATCGCCTAGGAATCTATCATAGTCGCACTCTATATGAGTGCGTGGATTGAAATTCAACGGGAAACAGGTTGGCACAGCAGGGGCCGACGAGTCGCACTCTATATGAGTGCGTGGATTGAAATACAACTCTATCAATCTCTTTATTTAAAGAACAGAAGTCGCACTCTATATGAGTGCGTGGATTGAAATCCAAGGAGGGAACTGATTTGGATGGACTCGTTATCGTCGCACTCTATATGAGTGCGTGGATTGAAATATGGAATCCGTCCTTACTGTCTGTCAGCAGCTTGGGTCGCACTCTACATGGGTGCGACGCATTAAAA

>NZ_CP020028|2|2|1792769-1794344|PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CACACAACTTCGGGGTCGTCCAGGTCTGGCAAGACCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTTTTGCTTGCAATGCTTGGTGCCTTTTTTGTAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTCCAGCGAAACAGACGTACCCGAAACGGCTTGCTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACAAGACTGAGGTCAAGGCCAAATTTGCGGACG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTTTGGATTTTTGGCATTGGCATATGCGGGGGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTTTCATCCAAATCTTTCCACCTCCTCACATAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCCTCCGGTATTCTTTTGCGCCCCAATTATATCCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CACTATAATTCCCAATGACATGGCAAACTGAATGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGGTGAACACCGTTACATTCATGAGTGCTTTCAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTACAAAAGAAAAGGCCACGTTTCACGTAGTTGTGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGAAACAGTCATTAATCTTCTGCCGCAAGCTGGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATGAATAAAAATAAAGTTTGCCAATACTTGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCGCTGGGGTCATTTCGTTTGTTAGGGGGGTGAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAAGCGTATGGACGAGCAAAACCACAATCTTTCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAGCAGCTACAGCAGCAGTTACAAGTCCTTTGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTATACGGAAAATGATTGGCCAATTTTTTGTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTTTCGCCCTCCTATCGTAACGCATTACCGCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGAGGGAAAAAACATCATATGGGACGCGCCACCTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTAACGGGCCTGTGGATAAGAAATGGACGAGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTATTTGACGTGTGATCGCCTAGGAATCTATCATA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCAACGGGAAACAGGTTGGCACAGCAGGGGCCGACGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAACTCTATCAATCTCTTTATTTAAAGAACAGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CCAAGGAGGGAACTGATTTGGATGGACTCGTTATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

>NZ_CP020028|2|2|1792769-1794411|CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CACACAACTTCGGGGTCGTCCAGGTCTGGCAAGACCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTTTTGCTTGCAATGCTTGGTGCCTTTTTTGTAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTCCAGCGAAACAGACGTACCCGAAACGGCTTGCTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACAAGACTGAGGTCAAGGCCAAATTTGCGGACG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTTTGGATTTTTGGCATTGGCATATGCGGGGGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTTTCATCCAAATCTTTCCACCTCCTCACATAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCCTCCGGTATTCTTTTGCGCCCCAATTATATCCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CACTATAATTCCCAATGACATGGCAAACTGAATGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGGTGAACACCGTTACATTCATGAGTGCTTTCAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTACAAAAGAAAAGGCCACGTTTCACGTAGTTGTGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGAAACAGTCATTAATCTTCTGCCGCAAGCTGGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATGAATAAAAATAAAGTTTGCCAATACTTGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCGCTGGGGTCATTTCGTTTGTTAGGGGGGTGAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAAGCGTATGGACGAGCAAAACCACAATCTTTCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAGCAGCTACAGCAGCAGTTACAAGTCCTTTGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTATACGGAAAATGATTGGCCAATTTTTTGTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTTTCGCCCTCCTATCGTAACGCATTACCGCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGAGGGAAAAAACATCATATGGGACGCGCCACCTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTAACGGGCCTGTGGATAAGAAATGGACGAGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTATTTGACGTGTGATCGCCTAGGAATCTATCATA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCAACGGGAAACAGGTTGGCACAGCAGGGGCCGACGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAACTCTATCAATCTCTTTATTTAAAGAACAGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CCAAGGAGGGAACTGATTTGGATGGACTCGTTATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATGGAATCCGTCCTTACTGTCTGTCAGCAGCTTGG
GTCGCACTCTACATGGGTGCGACGCATTAAAA

>NZ_CP020028|2|2|1792769-1794411|CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CACACAACTTCGGGGTCGTCCAGGTCTGGCAAGACCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCTTTTGCTTGCAATGCTTGGTGCCTTTTTTGTAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTCCAGCGAAACAGACGTACCCGAAACGGCTTGCTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACAAGACTGAGGTCAAGGCCAAATTTGCGGACG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTTTGGATTTTTGGCATTGGCATATGCGGGGGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTTTCATCCAAATCTTTCCACCTCCTCACATAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCCTCCGGTATTCTTTTGCGCCCCAATTATATCCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CACTATAATTCCCAATGACATGGCAAACTGAATGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGGTGAACACCGTTACATTCATGAGTGCTTTCAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTACAAAAGAAAAGGCCACGTTTCACGTAGTTGTGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGAAACAGTCATTAATCTTCTGCCGCAAGCTGGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATGAATAAAAATAAAGTTTGCCAATACTTGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCGCTGGGGTCATTTCGTTTGTTAGGGGGGTGAG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAAGCGTATGGACGAGCAAAACCACAATCTTTCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAGCAGCTACAGCAGCAGTTACAAGTCCTTTGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTGTATACGGAAAATGATTGGCCAATTTTTTGTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTTTCGCCCTCCTATCGTAACGCATTACCGCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGAGGGAAAAAACATCATATGGGACGCGCCACCTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTAACGGGCCTGTGGATAAGAAATGGACGAGGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTATTTGACGTGTGATCGCCTAGGAATCTATCATA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCAACGGGAAACAGGTTGGCACAGCAGGGGCCGACGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACAACTCTATCAATCTCTTTATTTAAAGAACAGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CCAAGGAGGGAACTGATTTGGATGGACTCGTTATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATGGAATCCGTCCTTACTGTCTGTCAGCAGCTTGG
GTCGCACTCTACATGGGTGCGACGCATTAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020028.1\|WP_094154402.1\|1796643_1797888_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173848
NZ_CP020028.1\|WP_094154394.1\|1786336_1787872_+\|DUF5123-domain-containing-protein	unknown	unknown	gnl\|CDD\|275079
NZ_CP020028.1\|WP_007431339.1\|1788547_1788976_-\|DUF4395-domain-containing-protein	unknown	unknown	gnl\|CDD\|379566
NZ_CP020028.1\|WP_094154404.1\|1798735_1799278_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP020028.1\|WP_094154407.1\|1802649_1803531_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094154401.1\|1796327_1796522_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|372570
NZ_CP020028.1\|WP_167383794.1\|1792065_1792449_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094154392.1\|1784072_1784777_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|238385
NZ_CP020028.1\|WP_094154396.1\|1789079_1789817_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377361
NZ_CP020028.1\|WP_007431336.1\|1790358_1790847_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380197
NZ_CP020028.1\|WP_094154400.1\|1794746_1796231_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376626
NZ_CP020028.1\|WP_010345281.1\|1808361_1808871_-\|discoidin-domain-containing-protein	unknown	unknown	gnl\|CDD\|366285
NZ_CP020028.1\|WP_094154397.1\|1789820_1790288_+\|kinase	unknown	unknown	gnl\|CDD\|130724
NZ_CP020028.1\|WP_094154406.1\|1800965_1802435_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376626
NZ_CP020028.1\|WP_094154408.1\|1803724_1808311_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|306825
NZ_CP020028.1\|WP_094154405.1\|1799394_1800597_-\|glycosyl-transferase-family-1	unknown	unknown	gnl\|CDD\|273616
NZ_CP020028.1\|WP_094154395.1\|1788178_1788526_+\|DUF2294-domain-containing-protein	unknown	unknown	gnl\|CDD\|378372
NZ_CP020028.1\|WP_167383793.1\|1784879_1785950_+\|thiazole-biosynthesis-adenylyltransferase-ThiF	unknown	unknown	gnl\|CDD\|181084
NZ_CP020028.1\|WP_094154403.1\|1798021_1798579_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|274100
NZ_CP020028.1\|WP_094154398.1\|1791413_1791632_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775

Protein	Function_ID	Function_description	E-value
NZ_CP020028.1\|WP_094154402.1\|1796643_1797888_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173848	cd01159, NcnH, Naphthocyclinone hydroxylase. Naphthocyclinone is an aromatic polyketide and an antibiotic, which is active against Gram-positive bacteria. Polyketides are secondary metabolites, which have important biological functions such as antitumor, immunosupressive or antibiotic activities. NcnH is a hydroxylase involved in the biosynthesis of naphthocyclinone and possibly other polyketides.	2.64414e-80
NZ_CP020028.1\|WP_094154394.1\|1786336_1787872_+\|DUF5123-domain-containing-protein	gnl\|CDD\|275079	TIGR04247, nitrous_oxide_maturation_protein_NosD, nitrous oxide reductase family maturation protein NosD. Members of this family include NosD, a repetitive periplasmic protein required for the maturation of the copper-containing enzyme nitrous-oxide reductase. NosD appears to be part of a complex with NosF (an ABC transporter family ATP-binding protein) and NosY (a six-helix transmembrane protein in the ABC-2 permease family). However, NosDFY-like complexes appear to occur also in species whose copper requiring enzymes are something other than nitrous-oxide reductase.	9.37635e-10
NZ_CP020028.1\|WP_007431339.1\|1788547_1788976_-\|DUF4395-domain-containing-protein	gnl\|CDD\|379566	pfam14340, DUF4395, Domain of unknown function (DUF4395). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 142 and 168 amino acids in length. There are two completely conserved C residues that may be functionally important.	5.09267e-26
NZ_CP020028.1\|WP_094154404.1\|1798735_1799278_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.32925e-34
NZ_CP020028.1\|WP_094154395.1\|1788178_1788526_+\|DUF2294-domain-containing-protein	gnl\|CDD\|378372	pfam10057, DUF2294, Uncharacterized conserved protein (DUF2294). Members of this family of hypothetical bacterial proteins have no known function.	1.88619e-35
NZ_CP020028.1\|WP_094154392.1\|1784072_1784777_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|238385	cd00756, MoaE, MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. Moco contains a tricyclic pyranopterin, termed molybdopterin (MPT), which carries the cis-dithiolene group responsible for molybdenum ligation. This dithiolene group is generated by MPT synthase in the second major step in Moco biosynthesis. MPT synthase is a heterotetramer consisting of two large (MoaE) and two small (MoaD) subunits.	2.04566e-52
NZ_CP020028.1\|WP_094154396.1\|1789079_1789817_+\|hypothetical-protein	gnl\|CDD\|377361	pfam04446, Thg1, tRNAHis guanylyltransferase. The Thg1 protein from Saccharomyces cerevisiae is responsible for adding a GMP residue to the 5' end of tRNA His. The catalytic domain Thg1 contains a RRM (ferredoxin) fold palm domain, just like the viral RNA-dependent RNA polymerases, reverse transcriptases, family A and B DNA polymerases, adenylyl cyclases, diguanylate cyclases (GGDEF domain) and the predicted polymerase of the CRISPR system. Thg1 possesses an active site with three acidic residues that chelate Mg++ cations. Thg1 catalyzes polymerization similar to the 5'-3' polymerases.	6.50684e-41
NZ_CP020028.1\|WP_007431336.1\|1790358_1790847_-\|hypothetical-protein	gnl\|CDD\|380197	NF033194, lipo_EMYY, EMYY motif lipoprotein. Members of this family are lipoproteins, about 300 amino acids long in precursor form, found broadly in the genus Staphylococcus and in some related species.	1.1873e-07
NZ_CP020028.1\|WP_094154400.1\|1794746_1796231_+\|hypothetical-protein	gnl\|CDD\|376626	pfam01835, A2M_N, MG2 domain. This is the MG2 (macroglobulin) domain of alpha-2-macroglobulin.	0.00031751
NZ_CP020028.1\|WP_010345281.1\|1808361_1808871_-\|discoidin-domain-containing-protein	gnl\|CDD\|366285	pfam00754, F5_F8_type_C, F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.	3.68025e-05
NZ_CP020028.1\|WP_094154397.1\|1789820_1790288_+\|kinase	gnl\|CDD\|130724	TIGR01663, polynucleotide_kinase-3'-phosphatase, polynucleotide 5'-kinase 3'-phosphatase. This model represents the metazoan 5'-polynucleotide-kinase-3'-phosphatase, PNKP, which is believed to be involved in repair of oxidative DNA damage. Removal of 3' phosphates is essential for the further processing of the break by DNA polymerases. The central phosphatase domain is a member of the IIIA subfamily (TIGR01662) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. As is common in this superfamily, the enzyme is magnesium dependent. A difference between this enzyme and other HAD-superfamily phosphatases is in the third conserved catalytic motif which usually contains two conserved aspartate residues believed to be involved in binding the magnesium ion. Here, the second aspartate is replaced by a conserved arginine residue which may indicate an interaction with the phosphate backbone of the substrate. Very close relatives of this domain are also found separate from the N- and C-terminal domains seen here, as in the 3'-phosphatase found in plants. The larger family of these domains is described by TIGR01664. Outside of the phosphatase domain is a P-loop ATP-binding motif associated with the kinase activity. The entry for the mouse homolog appears to be missing a large piece of sequence corresponding to the first conserved catalytic motif of the phosphatase domain as well as the conserved threonine of the second motif. Either this is a sequencing artifact or this may represent a pseudo- or non-functional gene. Note that the EC number for the kinase function is: 2.7.1.78.	2.39402e-11
NZ_CP020028.1\|WP_094154406.1\|1800965_1802435_+\|hypothetical-protein	gnl\|CDD\|376626	pfam01835, A2M_N, MG2 domain. This is the MG2 (macroglobulin) domain of alpha-2-macroglobulin.	0.00891821
NZ_CP020028.1\|WP_094154408.1\|1803724_1808311_+\|hypothetical-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	9.42665e-08
NZ_CP020028.1\|WP_094154405.1\|1799394_1800597_-\|glycosyl-transferase-family-1	gnl\|CDD\|273616	TIGR01426, Glycosyl_transferase, glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance].	4.09362e-117
NZ_CP020028.1\|WP_094154401.1\|1796327_1796522_+\|IS3-family-transposase	gnl\|CDD\|372570	pfam13333, rve_2, Integrase core domain.	0.00143571
NZ_CP020028.1\|WP_167383793.1\|1784879_1785950_+\|thiazole-biosynthesis-adenylyltransferase-ThiF	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	0
NZ_CP020028.1\|WP_094154403.1\|1798021_1798579_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|274100	TIGR02366, conserved_hypothetical_protein, probable dihydroxyacetone kinase regulator. The seed alignment for this family was built from a set of closely related uncharacterized proteins associated with operons for the type of bacterial dihydroxyacetone kinase that transfers PEP-derived phosphate from a phosphoprotein, as in phosphotransferase system transport, rather than from ATP. Members have a TetR transcriptional regulator domain (pfam00440) at the N-terminus and sequence homology throughout.	6.0686e-08
NZ_CP020028.1\|WP_094154398.1\|1791413_1791632_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	4.56791e-07

>NZ_CP020028.1|WP_167383794.1|1792065_1792449_+|hypothetical-protein
MLRIGPDAWHVRNAMQIILNSVVRRNAFVSRLVNVNREDICKLLCIMKNEYLLHNQLSDEAFMHMYGVNPVEALSIYFLESVDIHIHWEWRDAGGTSEKAIQYKKEVPFMTLNQAIERAEGERNACT
>NZ_CP020028.1|WP_094154398.1|1791413_1791632_-|helix-turn-helix-transcriptional-regulator
MLKLRIKLKEVLKEKGITQKQLEELSGVSQARISKLSSGDRQEVNLLMLEKIAHALDIRDISVLLQFEEEKI
>NZ_CP020028.1|WP_007431336.1|1790358_1790847_-|hypothetical-protein
MKKLSVFMLVLCCFSILAACSTDPIKKDLITYVNDGVLPLAQDEKAITEKYESVTGDKYTDDVTLYNTLRDDIIPEYTKYLDKVEAVKTETPEVRAVHETYIKAVSTQKEAFITMVDALEKQDLNLINESNTKLSEGKKLFRDFGEQLNTLAKEHDVTMNKK
>NZ_CP020028.1|WP_094154397.1|1789820_1790288_+|kinase
MECVIFIGIQASGKSTFYKEHFFKTHMRINLDMLKTRNRENVYLQASIDTMQRFVVDNTNPTVVERKKYIDACKNKGFKIIGYYFEPNFVESIKRNEERTGKEYIPEIGIKSVMSKLEAPNYEEGFDELYSVISSEGAFQIKKLPENHTINGGDT
>NZ_CP020028.1|WP_094154396.1|1789079_1789817_+|hypothetical-protein
MKKDDFGNRMKGYENAYRLSLPRRLPVIIRIDGAHFHTFTRGMTKPFDENLILALWETCKYLAQNIMGCKLVYHQSDEISLLLTNYDKLTTQSWFENNLQKMVSISASLATAKFNEEIQKVYPDKPLATFDARAWVLPHDEVANYFLWRQQDATKNSISMVAQAHFRHSELEGLNGNQLQDKLFTEKGLNWNNLPVWQKRGICITKQQYHKGEAIRSKWDVDHETPVFSQKRDYINQYVYLDKDV
>NZ_CP020028.1|WP_007431339.1|1788547_1788976_-|DUF4395-domain-containing-protein
MSQAAASIPRPLVRVNQWVIVLSVVFTWITGVYWVLAIPLVAGLLGVIFNFNPVMRVAKLFLKKSPSSYIQEDRGQQRFNQLLAVFFLLVAWVGFIFQWSIVAYVFSAMVLVAAVVAILGFCIGCFILYQWSQYQYRRRKHV
>NZ_CP020028.1|WP_094154395.1|1788178_1788526_+|DUF2294-domain-containing-protein
MRRETGFNEIIRKVRKELFGKGPERIHTTFVDNMAITILYGNLTPSEKFLAQEASGKEMVHAARTKMVQKIYPVQFNKELEDYMDSRLLHLFSDIKVEEDIAISVFVFEDNITAK
>NZ_CP020028.1|WP_094154394.1|1786336_1787872_+|DUF5123-domain-containing-protein
MMKFGKIFLAGLTMILGLGLMAGNVQPLSASAAGTEYYVATSGSDSNAGTNDAPWKTLQHAADVAPAGSTVYVRGGVYNQKLKITRSGSASQGPIVFTNYGTETAVIDGTGLSVSGTQGLIELANVDYVTVQGFEIRNFATASKNAVPVGIYVHGSGGFINLSNNKIHDIKNTVTPTGKDRLGRDAHGIAIYGTKAPASIHDLTISGNELYNLVLGSSESLVLNGNVDGFAVTDNLIHNNDNIGIDLIGFEGTAPNTAYDQARNGLVKGNRVYNNSSNKNPSYTKDDNSAGGIYVDGGKDSIIEQNYSYSNDIGIEIASEHAGKATSNITVRSNVIYNNRLTGIAMGGYDDERGSTVNCKIVNNTLYKNDTLGGGSGQLFVQYDTQNNVIKNNIFVASSTDVLIYNEYTKNSGNVVDYNLYFAPAGSSEASWTWKNKEYTGFLAYKKGTGNDAHSLFIDPKFVNAANGDFHLQSSSPAIDAGDTDRAIIGTLDIDGKSRVQGAAVNIGAYE
>NZ_CP020028.1|WP_167383793.1|1784879_1785950_+|thiazole-biosynthesis-adenylyltransferase-ThiF
MNKDQTTGTDAQAHTHASPARYSRQELFSKIGTAGQQNIRSKHVLMVGAGALGTANADMLVRAGIGRLTLVDRDYVDWSNLQRQQLYDEADARNQMPKAVAAQKRLQQINSDVDIRALVRDVSLEEIDDIAAGVDLIIDATDNFDTRLLMNDYAVKHRIPWIYGACVGSYGTTFTIVPGQTPCLHCLLGAVPLGGATCDTVGVISPAVQMVAAYQSAEALKLLTGDDSALQSKLITFDLWNNQHQAIHVSAMKKADCPTCGEHPVYPFLQSEHQAKTAVLCGRDTVQIRPAPGAVRDLNEAARLLSRQGGKVDHNPYLVSVVIGTHRLVLFQDGRVLVHGTKDIAEARSIYHKYLG
>NZ_CP020028.1|WP_094154392.1|1784072_1784777_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MQYRIQLSAAMAEQFGDVITVELSQEIVTIADIRKRLYEQYSEVASQLQGSFFTHHKRLASPDEPVLPSDAIALLQSAPGMETVISKCGLFAITYDPIDADEVASKVQDPSHGASLTFNGTTREYTQGQRTVLLEYEAYVPMAMNTMKQIGDEIAERWPSTRTAMTHRLGTVRIGETSVVIAVSAAHRDACYEASRHAIERLKQIVPIWKKEVWEDGSEWKGHQLGGWNPHNTQ
>NZ_CP020028.1|WP_094154400.1|1794746_1796231_+|hypothetical-protein
MKRFRKVISVTLSSMLLLSFGMTANASASTEEKTDQAIQAASNVQLTTDKESVIKQLTRADKPESITDSVYTLTENINLATAQKSELKKRVTPSLKASSKSAVSAKATATVATASTATYSGTITEEGGTQFLYPIYLQPGELLQAQLDGPFSAQLDYDLYLYEFDMTTGDINSNPIDVSNYGTYVNNYEQGAASLPENVGARNTTGANKAYAIAVHAKKGSSINDPFYLTVAVSSNYDAYEPDDSAFHAYNFTVNDKGSSINFRTIHSSIDNDWYQVTVPASRNYDALNVKLDSISESYGYKAEVYAALSGNQMVLLPQTNHNVTLNTGTYYVRVYSTSQYSADHLYTLAINPVLRAGKIEITGYNSNGYYDYPTYSYGRHYRINGGSNLIVNGVVKTTDGQLVPNAPVTIVWLDKNWSEGSGNRTRTASTYTNDNGAFSVTLALPQSTGKNVDYISEIGSTHYYDLTGVAAQVDGTSISTTDIVYLFAYSLRN
>NZ_CP020028.1|WP_094154401.1|1796327_1796522_+|IS3-family-transposase
MRHVMMSIYEKVERIFGYRQLTLHLRSQTRKTINIEAYIHFYSNERLQAKLNGLSPMEYRTKTV
>NZ_CP020028.1|WP_094154402.1|1796643_1797888_-|acyl-CoA-dehydrogenase
MTSLSTENQLTASELQLLKNATELVPFLQKFANRIDEERHIPDEVIQKVSDAGLFKLGTPKKYGGHEVSIRAMVEIISEVAKGNGSVGWVVQIINGNNYNVSLALPSEVLNSIFDQEEEVRFCSVLQARKAIVKKVDGGYLVEDGFWGFGSGSKHATHALLNLKDVKSMQETPEMLLAVVPMSEITIVDDWYTMSLKGSASNSLEIKNVFIPEKYVTTQGLSQVNPLPVELTGRDRYKPYVQVITSITTGISAILGLARGAVEYFVEKAPSKGITMTTHTSQAEVGHIQYKVGLAAMKVESAHLHISRTIDNLEHHVQSGEKFSLKEFAQIQTDITYAAMLCWEAVDMLMAESGGSVIADSNRLSQIFRDIRGGSNHALTTASTGLELYGRILMGLPPQNVMTISAAPFLKNNE
>NZ_CP020028.1|WP_094154403.1|1798021_1798579_+|TetR-family-transcriptional-regulator
MDNKTNDDLRVRRTHKLLYSALLDLMEKQPFENITVKQICDLAMVHRTTFYTHFNDKFDLLSRALRQIADDELNFVDTFISPSEAIKEVFSVATKHKKLFSQLLSEERDSLRNLLRREMGVGIHKHLVKNTSLEENSIDIQIAIEAHIGAVLGVLNWWIENNMPIDKEDIYRKLDILTKLNSRDH
>NZ_CP020028.1|WP_094154404.1|1798735_1799278_-|GNAT-family-N-acetyltransferase
MSEQQVYVRFSEEADAAELTAMYKRNREFFDKFSPSSLEKHYSEDHQLQKIIKSKADRIEDRKYSFVVCHKEDGRIIGSIDLSFVVRGPLQSCMIGYSLDQAYNGKGYMTEAVKQVVRYAFDELKFHRIVGEASPRNPGSIRVLEKAGFHKEGISRSNVKINGKWEDHQVLAIINPSEDI
>NZ_CP020028.1|WP_094154405.1|1799394_1800597_-|glycosyl-transferase-family-1
MARVLFINGGSEGHINPTIGVVQELISRGEEVVYFSIEAFRERIEKTGASVRTFDDQKFIKAFISGGRDYLLERTNGLLLTADIVIPSVLEQIKGEHFDYIIHDSMFGCGRLLAQILKLPAINSCTSFAQTKVSFDKMLEQFSIQVPTEIVKPINDKFQSLTVMAKEKYDVEIHSPYEVFCNPAPLTIVYTTREFQPYGEAFDQTYKFVGPSISSRLIQENFDLTAIKGKNPIYISLGTVFNQAIDFYKLCFEALGNTDHTIVMSIGNKTQITDLGEIPKNFIVKNYVPQTDVLQYTKLFITHGGMNSTHEGLYYGVPLIVIPQSADQPIIAGQVANIGAGINLQMQSLTANQLREAVDHVLSLSSFKNSVANIRESFQKSGGYHQAVDEIFEFKSQYHI
>NZ_CP020028.1|WP_094154406.1|1800965_1802435_+|hypothetical-protein
MKRFKKAIAVMLSTMLLFAFGMTANASQGTEAASDQAIRAESEIHLTTGNKDIIKRLTRVDKPDSVTSSVYVLQEKLNFKTPETTSLKKETVSSLKASPMAALATASSATYSGTITQEGGLQFLYPIYLQPGEMLQAQLDGPFSAQLDYDLYLYEFDMTTGDINPNAIDASTYGTYFNNYDQGAASLPENVGTRNAAGYEKAYAIAVHAKKGSSINDPFYLTVETSSSYDVYEPDESAFHAYNFTFSTGGSSLNSRSIHSGIDNDWYQITIPANRNYDALNVKLDNTSESYGYKAEVYEALTGNQMVLLPQTNHNVSLNTGTYYVRVYTTNQYSPDHLYTLTLKPVLRAGKIVINGYDSKNGPNDYPSYSYGRHYRADQRSNLTVKGVVSTTDGYAVANAPVDVTWLNQNWTEGSGNRTRTGTAYTDQNGAFSVTLSLPSSTGSIAEYLPGPISFTHYYDLSGVAAQVSGTSIIDTDIVYHFAYSVYGG
>NZ_CP020028.1|WP_094154407.1|1802649_1803531_+|hypothetical-protein
MNFGPLRAQQAVLNSSSLRINPASKQGVPSPQLHEEKVSRFVVQDSVEISETGRQLAEGAIVSQAAKYFGTTQINDSLNRVLEGQPEEVSNAVYNMIQSNFIVDGTVTDENQRAVLLEMGVSQSKYIADHYMEGDKAKEFLETMNQIAGIALTRSIDSESGDISYTTPADRPLGAPEDYVKLSEVMKQADPQQYAAFMNDIKGGGNGLNQLLSFAQKVPQHPDWINNYKERTGQTEELLNNTQLKNRFDKADTTSASAFMNSMQNLLKEASATQDSYMQNMRGFFRNLGVQVD
>NZ_CP020028.1|WP_094154408.1|1803724_1808311_+|hypothetical-protein
MYRKNKRKARKHSKWVYGFLAVLLLLTMIPIFPERVSAATQEIIGGPFCQNNLPGGGDSWGSPSGSGVGATEVYSGMGSARYKCDGSVQPTNRFIDIGRSIKTADYRVFVYIEGSYHTEISASNDAGGSNWRPDGTNLYTWTNVTKFYADSFYQGKWVEITDSITLRDIRYFRAMGYNQQTSNEISRFGIRLIPKSDLLPTPPQIHAGAEGQAVTGWTKEPVTVWINGDVAPEGLKYYEYSLNGGSFQPYTGPFTVYDHGVNTIYARTVDVNNQYSGLSSGKVRIDKMPPTPPTISATGNSNDYAISLQPGTDDYAGLAHTQFRMTGVVNQGWQDYGGMFHVNKDGKSTIYARSIDSVGNMSQEVSKEVIIDKKGPTAPTIRVSEAGPTARDVNIAIDSGSDPANGIKMTQYRLSPMGEWQTYLGVFTLTAEGNYELSARTINNLDVPGPTATQSVMIDRTKPTPPEITFSEVTMPTRYTNKPVQFALSGAMDITAVHYEYQWGSGGYVPGSSGILNRSGIVKVTAQAVDAAGNRSDPVSATSYIDLEPPTVQLTPNSREWKDSSMDVEIRYTDQHSGIEPATMQYRITNSPDSPEYWDTAANTAIRLSLLNEGEWYVHAKVKDRAGNISQTVSGALHIQKQPEPVVLSATSIRNTEADLQWTLPSGFNDGYVYTIRNLTTQEVWEVAHPTNSFTDKGLRGGRQYEYEVRVSNHVGGNAYSNRVRVLTLPDAPDHIRLKAVSHHPADILADFTPVASANKYNMIATDVSTGEVIFRDTVTQDVYNPITGMKPGKYYDVSVSAMNDTGEGAAKHVSFLSLPDSPAGFQNVTVREDGVELKWNDVVTATYYALERDNVSVYNDVYTEYTDTDLQAGTEYNYRISAKNTTGFGDYAHLGVITLPARVTTLASVTKDVYSVGVAWQDVQGADGYILNVNDEPNMRVPRGIHSYTFEGLPAGRSSSIRIRAYNRSGISQDATINELTLPVSAVQLAAVDVGEHEATLKWDPVDGATQYKITINDQDYYSTEPFVAVSGLEGGKNYNYQVSSGNSSGFSQPAWGELLTLPPQVQNVKVTELGNGQISLSWNETESAYEYAVIRRDTGEVLDTRDAHIKLSGIQPGMIYSFGIQAMNTSGAGDIAPFTYRALPDEIPDNRLIIKDITDTNLVVTWKEAPGGDAYNVYQNGVLIGHTDHHEFEIDRLDSSTVYLIAVNPANTSGEGKPTEAEVETLPSPDFKLSKTETTNNEFIIHWESEHKNDIFVLTSEGGTELYRGKERSFIWRQLREKQLYTVQLWAENSQGKRTEAKQVNGKTTGNPVDTGGGAGGAGVAKPIQPVVKEQIETKFIQSPSVETKSNHFSDIDRVFNRDKINALADLGVVKGMTPTLFEPNRPVTRMEFTSMLVRSLKLPLETDVTLGFEDINPSAWYVDLLKTAIKDQVARGFSDREFGPDRVINREQAAKMVNNVIKATPQHESSVYSDTSQIVEWARTDVLGLTEINLVQGYPDGSFRAKQEVTRAEAAEMIYNMLQMK
>NZ_CP020028.1|WP_010345281.1|1808361_1808871_-|discoidin-domain-containing-protein
MTKFNQNPENYSFFMNPVVIAEENVSTNGDSKNTFPKNVLVDNNLYWESSLSGKGGEIIFKLDEGKTINDILLAQPTFRAFILSFSFHGSNDGVNWFRLGQVETLPTTAKTTYQFSNEIPFQYYKITVLSSGLNSSTSYYGIRYIELRTALINGVPAYRASNLNPAIAE

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Crispr_ID: NZ_CP020028_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020028_3

3336456-3337893

TypeI

I-C

Consensus_repeat	Method
GTCGCACTCTGTATGAGTGCGTGGATTGAAAT	PILER-CR
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CRT

21 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP020028_3

>merge|NZ_CP020028|3|3336456-3337893|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATCCACGCACTCATACAGAGTGCGACTGCGAAAATAATCTTGCAGCAAGAGGGTGAATCTATTTCAATCCACGCACTCATACAGAGTGCGACTTGATACTCCAGGAGATTTTAGACGAAATTTCAGAATTTCAATCCACGCACTCATACAGAGTGCGACTTCGATCACCAAACGTTTAATGCCATAAGCCACAATTTCAATCCACGCACTCATACAGAGTGCGACGTCGATAGCATCTTCGGCCCTCTCCTCGGGTGGTTATTTCAATCCACGCACTCATACAGAGTGCGACCGGTCAGTTTACACATCCAACATTAAAAAAATCGGTATTTCAATCCACGCACTCATACAGAGTGCGACTTACCGGGAGATCATTAGCGCAGCAGTAGGACGATTATTTCAATCCACGCACTCATACAGAGTGCGACTCCCAATTATCGTTCATCATAGTTTCCACATCAAAATTTCAATCCACGCACTCATACAGAGTGCGACATAACGAGGAAGTGGGGTGGCTTTAAGCAATGAGTATTTCAATCCACGCACTCATACAGAGTGCGACGAAAAAGGACTTTTGAAGATGTCCGAAGCCCAATGATTTCAATCCACGCACTCATACAGAGTGCGACCAGGCCAGGAGACAAGGGTTATAGCGGATACAAGAACATTTCAATCCACGCACTCATACAGAGTGCGACCCTGGATAGGCACTTGCAGTAGGCACGAGAAAGAGATTTCAATCCACGCACTCATACAGAGTGCGACATGGTATCGGTAGGTTCTTGCAACGTGGCAATGCATTTCAATCCACGCACTCATACAGAGTGCGACTCTAGTCCGACGTACCTTAAATGGTATCGCCATTAATTTCAATCCACGCACTCATACAGAGTGCGACTGGTGTATTGAAATTTGTATTTCTTATTGGAATTTAAATTTCAATCCACGCACTCATACAGAGTGCGACAAACTTATGCCAGCTGCCCACAGCGTCCAGCACATATTTCAATCCACGCACTCATACAGAGTGCGACTGTCTTGGAACACGGTCACATCGCCGTATTTCCAATTTCAATCCACGCACTCATACAGAGTGCGACATTTTCGCGGTGGTTCCAGGTTCTTGGTGAAACAATTTCAATCCACGCACTCATACAGAGTGCGACAAGGTCTATCGACATAGCATATGCGCTCAGGATCGATTTCAATCCACGCACTCATACAGAGTGCGACCTGGATAGGCACTTGCAGTAGGCACGAGAAAGAGATTTCAATCCACGCACTCATACAGAGTGCGACGCTCTTGTAACTAACCATAACACTATGGTGTATTATTTCAATCCACGCACTCATACAGAGTGCGACTTTTTGTTAATCATAGCACTCCAAACGGGCAAAAAATTTCAATCCACGCACTCATACAGAGTGCGAC

>NZ_CP020028|3|3|3336456-3337893|PILER-CR
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGCGAAAATAATCTTGCAGCAAGAGGGTGAATCT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTGATACTCCAGGAGATTTTAGACGAAATTTCAGA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTCGATCACCAAACGTTTAATGCCATAAGCCACA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GTCGATAGCATCTTCGGCCCTCTCCTCGGGTGGTT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CGGTCAGTTTACACATCCAACATTAAAAAAATCGGT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTACCGGGAGATCATTAGCGCAGCAGTAGGACGATT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TCCCAATTATCGTTCATCATAGTTTCCACATCAAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATAACGAGGAAGTGGGGTGGCTTTAAGCAATGAGT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GAAAAAGGACTTTTGAAGATGTCCGAAGCCCAATG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CAGGCCAGGAGACAAGGGTTATAGCGGATACAAGAAC
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CCTGGATAGGCACTTGCAGTAGGCACGAGAAAGAG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATGGTATCGGTAGGTTCTTGCAACGTGGCAATGC
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TCTAGTCCGACGTACCTTAAATGGTATCGCCATTA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGGTGTATTGAAATTTGTATTTCTTATTGGAATTTAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	AAACTTATGCCAGCTGCCCACAGCGTCCAGCACAT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGTCTTGGAACACGGTCACATCGCCGTATTTCCA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATTTTCGCGGTGGTTCCAGGTTCTTGGTGAAACA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	AAGGTCTATCGACATAGCATATGCGCTCAGGATCG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CTGGATAGGCACTTGCAGTAGGCACGAGAAAGAG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GCTCTTGTAACTAACCATAACACTATGGTGTATT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC

>NZ_CP020028|3|3|3336456-3337893|CRISPRCasFinder
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGCGAAAATAATCTTGCAGCAAGAGGGTGAATCT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTGATACTCCAGGAGATTTTAGACGAAATTTCAGA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTCGATCACCAAACGTTTAATGCCATAAGCCACA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GTCGATAGCATCTTCGGCCCTCTCCTCGGGTGGTT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CGGTCAGTTTACACATCCAACATTAAAAAAATCGGT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTACCGGGAGATCATTAGCGCAGCAGTAGGACGATT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TCCCAATTATCGTTCATCATAGTTTCCACATCAAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATAACGAGGAAGTGGGGTGGCTTTAAGCAATGAGT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GAAAAAGGACTTTTGAAGATGTCCGAAGCCCAATG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CAGGCCAGGAGACAAGGGTTATAGCGGATACAAGAAC
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CCTGGATAGGCACTTGCAGTAGGCACGAGAAAGAG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATGGTATCGGTAGGTTCTTGCAACGTGGCAATGC
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TCTAGTCCGACGTACCTTAAATGGTATCGCCATTA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGGTGTATTGAAATTTGTATTTCTTATTGGAATTTAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	AAACTTATGCCAGCTGCCCACAGCGTCCAGCACAT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGTCTTGGAACACGGTCACATCGCCGTATTTCCA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATTTTCGCGGTGGTTCCAGGTTCTTGGTGAAACA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	AAGGTCTATCGACATAGCATATGCGCTCAGGATCG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CTGGATAGGCACTTGCAGTAGGCACGAGAAAGAG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GCTCTTGTAACTAACCATAACACTATGGTGTATT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC

>NZ_CP020028|3|3|3336456-3337893|CRT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGCGAAAATAATCTTGCAGCAAGAGGGTGAATCT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTGATACTCCAGGAGATTTTAGACGAAATTTCAGA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTCGATCACCAAACGTTTAATGCCATAAGCCACA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GTCGATAGCATCTTCGGCCCTCTCCTCGGGTGGTT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CGGTCAGTTTACACATCCAACATTAAAAAAATCGGT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTACCGGGAGATCATTAGCGCAGCAGTAGGACGATT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TCCCAATTATCGTTCATCATAGTTTCCACATCAAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATAACGAGGAAGTGGGGTGGCTTTAAGCAATGAGT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GAAAAAGGACTTTTGAAGATGTCCGAAGCCCAATG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CAGGCCAGGAGACAAGGGTTATAGCGGATACAAGAAC
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CCTGGATAGGCACTTGCAGTAGGCACGAGAAAGAG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATGGTATCGGTAGGTTCTTGCAACGTGGCAATGC
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TCTAGTCCGACGTACCTTAAATGGTATCGCCATTA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGGTGTATTGAAATTTGTATTTCTTATTGGAATTTAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	AAACTTATGCCAGCTGCCCACAGCGTCCAGCACAT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TGTCTTGGAACACGGTCACATCGCCGTATTTCCA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	ATTTTCGCGGTGGTTCCAGGTTCTTGGTGAAACA
ATTTCAATCCACGCACTCATACAGAGTGCGAC	AAGGTCTATCGACATAGCATATGCGCTCAGGATCG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	CTGGATAGGCACTTGCAGTAGGCACGAGAAAGAG
ATTTCAATCCACGCACTCATACAGAGTGCGAC	GCTCTTGTAACTAACCATAACACTATGGTGTATT
ATTTCAATCCACGCACTCATACAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATACAGAGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020028.1\|WP_007430135.1\|3350768_3351521_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP020028.1\|WP_094155396.1\|3334895_3335270_-\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP020028.1\|WP_094155397.1\|3338074_3338365_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP020028.1\|WP_094155401.1\|3340968_3342933_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP020028.1\|WP_094155392.1\|3329329_3330196_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP020028.1\|WP_094155395.1\|3333833_3334829_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP020028.1\|WP_094155403.1\|3343762_3346252_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP020028.1\|WP_094155393.1\|3330304_3331645_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270303
NZ_CP020028.1\|WP_094155398.1\|3338374_3339406_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP020028.1\|WP_094155399.1\|3339402_3340062_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP020028.1\|WP_007430139.1\|3335443_3335638_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094155394.1\|3332657_3333344_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_CP020028.1\|WP_094155389.1\|3324834_3325389_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094155404.1\|3348903_3349713_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP020028.1\|WP_094155391.1\|3328476_3329316_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP020028.1\|WP_094155400.1\|3340048_3340924_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP020028.1\|WP_094155390.1\|3325503_3328026_-\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP020028.1\|WP_157739746.1\|3331715_3332618_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|224868
NZ_CP020028.1\|WP_094155402.1\|3342929_3343649_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP020028.1\|WP_094155405.1\|3349919_3350756_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223704

Protein	Function_ID	Function_description	E-value
NZ_CP020028.1\|WP_007430135.1\|3350768_3351521_-\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	7.74466e-08
NZ_CP020028.1\|WP_094155396.1\|3334895_3335270_-\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	4.30763e-32
NZ_CP020028.1\|WP_094155397.1\|3338074_3338365_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.16279e-30
NZ_CP020028.1\|WP_094155401.1\|3340968_3342933_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	2.22684e-173
NZ_CP020028.1\|WP_094155392.1\|3329329_3330196_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.57177e-72
NZ_CP020028.1\|WP_094155395.1\|3333833_3334829_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	9.7516e-115
NZ_CP020028.1\|WP_094155403.1\|3343762_3346252_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.53036e-76
NZ_CP020028.1\|WP_094155393.1\|3330304_3331645_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.14223e-72
NZ_CP020028.1\|WP_094155398.1\|3338374_3339406_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP020028.1\|WP_094155399.1\|3339402_3340062_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.31988e-27
NZ_CP020028.1\|WP_094155394.1\|3332657_3333344_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.21748e-36
NZ_CP020028.1\|WP_094155404.1\|3348903_3349713_-\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.05951e-88
NZ_CP020028.1\|WP_094155391.1\|3328476_3329316_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	9.50819e-76
NZ_CP020028.1\|WP_094155400.1\|3340048_3340924_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.09552e-126
NZ_CP020028.1\|WP_094155390.1\|3325503_3328026_-\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP020028.1\|WP_157739746.1\|3331715_3332618_-\|nucleoside-hydrolase	gnl\|CDD\|224868	COG1957, URH1, Inosine-uridine nucleoside N-ribohydrolase [Nucleotide transport and metabolism].	1.54092e-77
NZ_CP020028.1\|WP_094155402.1\|3342929_3343649_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.8465e-94
NZ_CP020028.1\|WP_094155405.1\|3349919_3350756_-\|hypothetical-protein	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	0.00105695

>NZ_CP020028.1|WP_007430139.1|3335443_3335638_-|hypothetical-protein
MKKRNAVTPYGWKIKQKLVEKQMDQGTFCDTYHIPPSRLSNLIHGTRKAKKYRKLVSELLGLEE
>NZ_CP020028.1|WP_094155396.1|3334895_3335270_-|DUF1992-domain-containing-protein
MGMFFRMAEQKIAEAMAKGEFDHLPGAGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQQECVQMRDLLHACHEAGEQQRISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAVRKRLEE
>NZ_CP020028.1|WP_094155395.1|3333833_3334829_+|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQDQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYILRIEDIDMTRARSPLAQGIMEDLRWIGLEWDEGPDVGGPYGPYTQSQRLERFQAALDKLQGQDMLYPCFCSRADIVAAASAPHGLSGEGPAYSGTCRSLTPQEAETNSQHKLPSLRFKVPQNSDAVISFHDQVAGHAIFGAGDGGDFIVKRADGMFSYQLAVVVDDADMHITDVLRGYDLLDSTPRQLLLYQALGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGITPEAVIGWLAYFSGLLDSPEPVKAVDLVQDFHLDKLPKEPVILTEQFFRRLSDLQR
>NZ_CP020028.1|WP_094155394.1|3332657_3333344_-|Crp/Fnr-family-transcriptional-regulator
MLDLAAKTVSTGSKASKRSIDSVYALHRKYGTLRRFPKGSFVFTKGSVPVGSYFIENGLLKVCQFTEEGRDVTFFIRKTGDAFGLAEIVLGQNHPCYAQCLHDSQIWVLDAAIIQEKIHSDHEVMSDILYTMTDRLIHHQSTVELLISKPVPWRLAWLLQQLGTPVGDGDSRIDLVLNHEEISNMIGCSRQTVSELLSKWKAQGIISYDRKHIVLHNVQAIFGASGMN
>NZ_CP020028.1|WP_157739746.1|3331715_3332618_-|nucleoside-hydrolase
MSRIILDTDIGTNADDAVALALALRSTEIRIEGITTVYGKVRTRAQIAQKVLNLCGACHIPVCPGIELPLLRNRPLLRAGIEGKGLHLEESGSKFDRHAVDFIMQSVMEHPGEITLVMIGPHTNVAAAMIREPRIAECVKQIVMMGGVTRLAPNGSDLSPVEHNIQCDPEAAAIVFSSGAPILMLGLDVTRQAVFSREEADLMGASGTPLAGTLVRMMHDFMDYMQRDFSYMCDPLAIAVLIDPTLIRTKRMDIRVQYERGEFSGQTIAEACADGNVETALEVDTARFFELLNHRLFFTG
>NZ_CP020028.1|WP_094155393.1|3330304_3331645_-|sugar-ABC-transporter-substrate-binding-protein
MIPKQPVKRFAAWCAPMLAAAVLFTGCSQGAGTSADSSSSNGQGSSTSSATTEISFEAYSNYEKPLTKVVEAFEQQNPNIKVKMNLVPIDQLTETIEIKLSSKAEDLDVLFVDTPLVMNYSVKGYLEPLDSLIPADAKAKWTKSAVDTVSYKGELMAAPMNSSSQVLYYNKDIFKKKGIPFPDADKRMTWEEVRDLAKQLTSDNVYGFSFEQVDKAYQLLALSDSLSAKMLSDDGLVSSGYSNSPEAVKAFQFYADLFNKDKVSPKIKKEESIDYFTSGKVAMFVSTNQNMPKIRDSGLNFGVTLHPYFAGQKVATPTGAWNVGISKYSEHKEASAKFIKFLTLGEGAKILFKEGGTLPPQIDLLNSIDTDPKYEQFPDNVIRIAAKESRETAVPRPKTPGYLEWEKNMNKAFEDMKNGADPQKALDDAVHVIDNLLKKYKGVAAN
>NZ_CP020028.1|WP_094155392.1|3329329_3330196_-|sugar-ABC-transporter-permease
MKLKNNIGSILLFLLPTLAGLFLFKLYPIFSAVVQSVYTTQFFTGEKSFVGLQNYQSLFADPVFWNSLKVTLVFNLIINPLQIVLAFALAMLLNTKIKRIAFFRGIHFVPVAVSVPTACVLWNIMLSPEQGVVNSILVALGLDPQPFLGSSLQALGSIIAIASWKGVGYWSLFLLAGLQEIPGSLLEASSLDGASRWKQFVHVILPLMKRPLTFIVVAVTTANFLLFSPMYILTKGGPENSTNVLMLESFNNAFLYSDMGRSYAIMVILLLITLTVVALQFKWLRTSH
>NZ_CP020028.1|WP_094155391.1|3328476_3329316_-|carbohydrate-ABC-transporter-permease
MNRFTRSHLLLYAVHIVLALLVLLPLAFAFVSSFRPLEDIYKYMSPITWKTFWPSNFTWGAYQMLFTERGFGQIFLNTFFVGAANVIGGLLLGSMAAFAFVYFEFRGKTLLFLLVLLTFMIPFEVISIPLYSLVNSLGWVDTYAGIIIPGIANGLVIFLFRQFFLELPTSLVESARMDGASWLRVYTRIVMPLCKPVTVSASLLIFIQQWESFLWPLIVTRSKEYKVIQVALSDFVTEYATYWNEMFAAVILSILIPVVLLLPLQRYYVQGIANTGSKE
>NZ_CP020028.1|WP_094155390.1|3325503_3328026_-|ATP-dependent-helicase-HrpB
MTDKQLPIIQIIPELKNALRSHSAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMLMLEPRRLAARAAAAQMAKALGEQTGQTVGYRVRMDTKIGPNTRIEVVTEGVLTRMLQSDQALEGTGLIIFDEFHERSLHADLGLALALQSQALLRSDLKILIMSATLEAEPVCRLLGDAPLLECPGTVFPVETFHMPKPSSATLETFTAETVEKALHAHKGDLLVFLPGAREIHRTERELTSRNLSPHVKVIPLYGSMKLEQQDEAIRPSASGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEHAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDAPPEAAYRQATGLLRQLGCLSTAADGSAGGITAHGREVSALGAHPRLGHMLLRAAALGLAPTASRLAALLQERDPFRAHGGTDLRPRLDALREAAHARSTHSLLRAADDTVIRRIVQESRQLLATLPKVAQDEPDGSASCGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLRQVEWMSRSSYLVAAEVDDEGADGAIQLAAPVELQELIEHCSEWLLEQAHVYWDSSASAVRARKILQLGALVLKETSYERPPAEEIAGALMVGVRERGLKLLSWNRSTLQLQARLIFMHFSAPEDWPDSSESALLDSLESWLLPFALGAKNVSDLQRLDGSELLLGRLDWEQRQQLEQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGLRETPRIGRGRVPLVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVATSRAKPKR
>NZ_CP020028.1|WP_094155389.1|3324834_3325389_+|hypothetical-protein
MNNGLDGYKCQYSGINPVLDRILERWTGEPKKTVYLLINKYGLPNDASWTKITWYNNGPWKRTVVHLRTVPHNTPTPHLDYLAQTIDYRVPVQFFGDLARFDGSLYPDRTAGEATAKCDQEAANFMALNLMNDIITGKRTVEDARHAAVEIEKAFRLKGQSSPYTTGFLFQKQFHTADPDVAYF
>NZ_CP020028.1|WP_094155397.1|3338074_3338365_-|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSTQFRRLKYELEELIDKKEDSLRFYNLGDNYKKKVEHIGVKEAYDMESPLIL
>NZ_CP020028.1|WP_094155398.1|3338374_3339406_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVVKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDDRRSARVARNMIIGKIYNHKWILERATRDHQLRIDMDRMKKVSASLTEIMKQVREVEELDILRGLEGTAAVQYNSVFDELILQQKDDFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRESLALDVMEELRGVYADRFVLSLINKKLIHGTGFYRKENGSVMMDDDTRKIVLKAWQERKQDKIIHPYLNEKMSWGLVPYSQALLLARHIRGDLDEYPPFLWK
>NZ_CP020028.1|WP_094155399.1|3339402_3340062_-|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGIQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGDKLVVRALPVHSRELGITGICDVVEFVRDPLGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITASDRERVRASLQEMRHYFERNHTPKAKAGPHCQSCSLQHICVPEILNKKSVSSFIESRIAE
>NZ_CP020028.1|WP_094155400.1|3340048_3340924_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSILDHKIDFAVVLSVAKANPNGDPLNGNRPRQNYDGFGEISDVALKRKIRNRLQDMGESIFVQSNDRKSDSFSSLRERAEANPELGKIFKSKEGSSEEFARMACQEWMDVRSFGQVFAFKAVGKGAGVSVGVRGPVSIHTATSVLPIDITSMQITKSVNSEPGSEKGSDTMGMKHRVDFGVYVFKGSINTQLAEKTGFTNEDAAKIREALISLFENDVSSARPDGSMEVHKVYWWEHNSKLGKYSSAKVHRSLEVKPKENVNAADKSFDTHYECILTPLEGLEVQEYAGL
>NZ_CP020028.1|WP_094155401.1|3340968_3342933_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYESNLDRVGVIEKKHNDREYTLLPISHTTQNAQIEVEITEQGDFHSARVLDKDDFSTLIPCTEKSASRAGSVVAPYPLHDKLSYVAGDFVAYGGKIKKEEPFAAYIQQLEGWANSEYATPKLKSIYRYLSKRRLIKDLVDESILYLDEDQKLISKWEKKYERSPGEKPRIFTAVPGELESAFIRFNVYSPDKALTKVWQDKELYDSFIGYYSKLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFAHSHEAASISYEVSQKAHNALKWLIHRQGKTTMDNRVFLVWGNDATNVPSLTDNDNIFAMGFGTESSRPTAIKSHTNEELAFDLAKALSGYRNKLAVKADSKANVNILVLDSATTGRMAVLYYRNLDKKLYFDRLIDWHSKCAWLHRYQKDEQGELLLFWGAPATRDIAFAAYGPKANDKLIKGLMERMLPCIVDGRTIPQDIVRSATHRASNPVAMDKWEWEKTLSITCALINTREGYNVGLDEENTDRSYLFGRLLAIADVLERNALERSGQDKEKKRSTNAIRYMSVFSQHPERTWRTIQNALQPHQAKYGQSLNYYSIMIDEVASKIPFDQFNNEPLTGKYLLGFYSQRYKLYHNTDKKKHQANTTETNDSQNDNTPA
>NZ_CP020028.1|WP_094155402.1|3342929_3343649_-|type-I-C-CRISPR-associated-protein-Cas5
MRNAIEFRVYGDYALFTDPLTKLGGEKLTYSVPTYQALKGIVESIYWKPTITMVVDKVRVLNAIRMESKGIRPIEYGGGNTLANYTYLKDPCYEVQAHFIFNLHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGEAPGFYDSYGDIHLGNMVHGINYPDETGRNHLEVRLWNPVMKDGVIEFIPPEICTQVRIIADMQPKQFDENNVQSADELFAEWEGWGMK
>NZ_CP020028.1|WP_094155403.1|3343762_3346252_-|CRISPR-associated-helicase/endonuclease-Cas3
MDYIAHIRESDHEIQTVADHLMETQQLAETYGDKIGIQHITGLAGMLHDLGKYTEKFQNYIRLAVQNPDIPPKRGSVDHSTAGGKLLYNLFHIQPQGPFDKQDFMNKALLSEVVGNAIISHHAYLQDFLDPDLESKFLDRVRDRKLEGFDHAVTLFYEQVMEESAFIHYVNQAGIELADYMKRDDNPDIELKMMFLSKFVFSALIDADRTNTRCFEEVNVKNEKNSNEPMIRQQLFQTYYERLMERITDLQSGENADTTINLLRKQMSEQCEQFAVKPSGIFTLSIPTGGGKTLASLRYALKHAVTFEKKHIIYVVPFTTIIEQNAQEVREIIRDDANLLEHHSNVVTNEVEDIDGEDHELEDVVVNTHQKLKLAKDNWDSPIIFTTMVQFLNVFYAGGSRNIRRLHNLSESVIIFDEVQKVPTHCTSLFNQALNFLKIYASSSIVLCTATQPELDFVHNKLDIDPDAEMVHDLDHVIEKFKRVEIVDKATDDTLDTEKLANFVEQKLADEPSILVILNTKAVVKNLYHRLTEGDGAIPIYHLSTSMCPAHRNRILGEVKTHLDHKEPVVCISTQLIEAGVDISFDCVIRSLAGLDSIAQAAGRCNRHGRDGTKQVYVIDHEEENLKDLKEIKIGKEITKKMFIDLKRDKTCYGGNILSGHAMEIYFQKYYTELASDLNYFIPKLRKNMTELLSVSRSENTYYRSYYDEHDTLLPLFLANSYKTAADHFQVIKDHTTAVIVPYGDGEKEGKEIIADLNGQQSIEDLSSLLRRAQQFTINITNTDKNQLSHNKALVSFLDGKIWALTDGAYDDSYGLNLQNDSSHGGFIL
>NZ_CP020028.1|WP_094155404.1|3348903_3349713_-|SDR-family-oxidoreductase
MSYTSARSARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERILETEKEINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIIFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTVPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKSERLKQITIPVQFPEGGQPLANGPGQPGQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP020028.1|WP_094155405.1|3349919_3350756_-|hypothetical-protein
MNPLLSLLPASKRKGMNARLAQHFAYISSQTGDQPLSSHLSRFLCRYGYGRSAESASMGESGQDFAAVRIHKSVCCFVLCDGVGLSYRGDFAARYLGSSLLDWLEEGRDLSADQLRMHLERLASTATEELNRQPLGHESGLMRSVLEDKRRQGSQSMYICGRIELPKRGTRGRLRLAWQGDSRLRLWNGTEEISELFDHTFSTAERWSTSRGPIGGKPHWYERSIPADMAMRLQVYSDGLSDLDPIREPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP020028.1|WP_007430135.1|3350768_3351521_-|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMSMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHNTPLQDEHAVKLRNMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR

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Crispr_ID: NZ_CP020028_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020028_4

3346618-3348657

TypeI

I-C

Consensus_repeat	Method
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CRISPRCasFinder
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	PILER-CR

30 spacers

cas3,cas5,cas8c,cas7,cas4,cas1,cas2

The CRISPR arrays of NZ_CP020028_4

>merge|NZ_CP020028|4|3346618-3348657|CRISPRCasFinder,CRT,PILER-CR
TGCTGTATCCATGCACTCACATAGAGTGCGACGCTGAATAAACAAGACTTACAAGAGGTGCAGAGATTATTTCAATCCACGCACTCATATAGAGTGCGACGAAGTCGGCTCCAATCTTCCATATGCCCACTACTTATTTCAATCCACGCACTCATATAGAGTGCGACCAATGTAAGTTTCAGATTTTTTTGGCTTCTCTTATTTCAATCCACGCACTCATATAGAGTGCGACGGCGACGCGAGAGTCTTCGAATATTTCTTTGATGATTTCAATCCACGCACTCATATAGAGTGCGACTTCAACATCAAAAAAATATGTATGATCTATTTCAATTTCAATCCACGCACTCATATAGAGTGCGACCACGAACGTTAGAGAGTTCCAAGTTTTCGGTGCTATTTCAATCCACGCACTCATATAGAGTGCGACAAATTCAAGGTTACTGCCGTGGATACATGGGGTAAAATTTCAATCCACGCACTCATATAGAGTGCGACTTATTGATGTGAAACAAAGTGCACATATGGTTGTTCGTATTTCAATCCACGCACTCATATAGAGTGCGACTTTAATTTTGTCTTCTATTATCTCCCAACGTTTAGGAGATTTCAATCCACGCACTCATATAGAGTGCGACAAACGCTTGAAACTTAAAATACAAGAGCTTGAAGGTATTTCAATCCACGCACTCATATAGAGTGCGACTTACTTTTGCGCCGCTTAAACTGCGAGAATGAAATTTCAATCCACGCACTCATATAGAGTGCGACCACAACTACGTGAAACGTGGCCTTTTCTTTTGTAAATTTCAATCCACGCACTCATATAGAGTGCGACATCGGTATGAGCCTCGTCCAAACAAATGATGGATATTTCAATCCACGCACTCATATAGAGTGCGACGAAAGCACACTATTGCTTATTCCAACACGCTCAGCAATTTCAATCCACGCACTCATATAGAGTGCGACTAATTATTTTGTTTGGTATCGGAGTTTGAAAAAATTTCAATCCACGCACTCATATAGAGTGCGACGATATTCGATTCGCATGACAATGATCTCTTGATTATTTCAATCCACGCACTCATATAGAGTGCGACTTTTTGTTAATCATAGCACTCCAAACGGGCAAAAAATTTCAATCCACGCACTCATATAGAGTGCGACGCCTGCAAAAGATGGTCATAGGCACCTCATTTTCAGATTTCAATCCACGCACTCATATAGAGTGCGACTCCGAAGAAAAAGGGAAATATTTCGCTATGGTACTTATTTCAATCCACGCACTCATATAGAGTGCGACTAGTCCCGGTCGTCATAGACCTTGTCTCTACGAAAGATTTCAATCCACGCACTCATATAGAGTGCGACGCAAAAAGCGCCAATTGTACACCGTCAAGCGAGAAATTTCAATCCACGCACTCATATAGAGTGCGACCAAAAAGCGCCAATTGTACACCGTCAAGCGAGAAATTTCAATCCACGCACTCATATAGAGTGCGACCATTGAATATCTGCGTCAAATCCAGTAGAATAAATTTCAATCCACGCACTCATATAGAGTGCGACGGATGATTGCAGCTGCTAATCAAAAACGATGGTGGATTTCAATCCACGCACTCATATAGAGTGCGACTTTTTGTTAATCATAGCACTCCAAACGGGCAAAAAATTTCAATCCACGCACTCATATAGAGTGCGACTCCAAACGGGCAAAAAGAAAAGCAGCTTTTTTGATTTCAATCCACGCACTCATATAGAGTGCGACGATATAATTGGGGCGCAAAAGAATACCGGAGGAAATTTCAATCCACGCACTCATATAGAGTGCGACTTCCCTCCCGACTGTTACTTTTTAACCATTTACAATTTCAATCCACGCACTCATATAGAGTGCGACTCGTGCCTACTGCAAGTGCCTATCCAGGTGGATTGCTATTTCAATCCACGCACTCATATAGAGTGCGACTGTCATTGGGAATTATAGTGGAAAAAATTAAGGGGTATTTCAATCCACGCACTCATATAGAGTGCGAC

>NZ_CP020028|4|4|3346618-3348657|CRISPRCasFinder
TGCTGTATCCATGCACTCACATAGAGTGCGAC	GCTGAATAAACAAGACTTACAAGAGGTGCAGAGATT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GAAGTCGGCTCCAATCTTCCATATGCCCACTACTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAATGTAAGTTTCAGATTTTTTTGGCTTCTCTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGCGACGCGAGAGTCTTCGAATATTTCTTTGATG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTCAACATCAAAAAAATATGTATGATCTATTTCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CACGAACGTTAGAGAGTTCCAAGTTTTCGGTGCT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAATTCAAGGTTACTGCCGTGGATACATGGGGTAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTATTGATGTGAAACAAAGTGCACATATGGTTGTTCGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTAATTTTGTCTTCTATTATCTCCCAACGTTTAGGAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAACGCTTGAAACTTAAAATACAAGAGCTTGAAGGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTACTTTTGCGCCGCTTAAACTGCGAGAATGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CACAACTACGTGAAACGTGGCCTTTTCTTTTGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ATCGGTATGAGCCTCGTCCAAACAAATGATGGAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GAAAGCACACTATTGCTTATTCCAACACGCTCAGCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TAATTATTTTGTTTGGTATCGGAGTTTGAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GATATTCGATTCGCATGACAATGATCTCTTGATT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCCTGCAAAAGATGGTCATAGGCACCTCATTTTCAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCGAAGAAAAAGGGAAATATTTCGCTATGGTACTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TAGTCCCGGTCGTCATAGACCTTGTCTCTACGAAAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCAAAAAGCGCCAATTGTACACCGTCAAGCGAGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAAAAAGCGCCAATTGTACACCGTCAAGCGAGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CATTGAATATCTGCGTCAAATCCAGTAGAATAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGATGATTGCAGCTGCTAATCAAAAACGATGGTGG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCAAACGGGCAAAAAGAAAAGCAGCTTTTTTG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GATATAATTGGGGCGCAAAAGAATACCGGAGGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTCCCTCCCGACTGTTACTTTTTAACCATTTACA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCGTGCCTACTGCAAGTGCCTATCCAGGTGGATTGCT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TGTCATTGGGAATTATAGTGGAAAAAATTAAGGGGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC

>NZ_CP020028|4|4|3346618-3348657|CRT
TGCTGTATCCATGCACTCACATAGAGTGCGAC	GCTGAATAAACAAGACTTACAAGAGGTGCAGAGATT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GAAGTCGGCTCCAATCTTCCATATGCCCACTACTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAATGTAAGTTTCAGATTTTTTTGGCTTCTCTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGCGACGCGAGAGTCTTCGAATATTTCTTTGATG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTCAACATCAAAAAAATATGTATGATCTATTTCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CACGAACGTTAGAGAGTTCCAAGTTTTCGGTGCT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAATTCAAGGTTACTGCCGTGGATACATGGGGTAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTATTGATGTGAAACAAAGTGCACATATGGTTGTTCGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTAATTTTGTCTTCTATTATCTCCCAACGTTTAGGAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAACGCTTGAAACTTAAAATACAAGAGCTTGAAGGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTACTTTTGCGCCGCTTAAACTGCGAGAATGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CACAACTACGTGAAACGTGGCCTTTTCTTTTGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ATCGGTATGAGCCTCGTCCAAACAAATGATGGAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GAAAGCACACTATTGCTTATTCCAACACGCTCAGCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TAATTATTTTGTTTGGTATCGGAGTTTGAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GATATTCGATTCGCATGACAATGATCTCTTGATT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCCTGCAAAAGATGGTCATAGGCACCTCATTTTCAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCGAAGAAAAAGGGAAATATTTCGCTATGGTACTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TAGTCCCGGTCGTCATAGACCTTGTCTCTACGAAAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCAAAAAGCGCCAATTGTACACCGTCAAGCGAGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAAAAAGCGCCAATTGTACACCGTCAAGCGAGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CATTGAATATCTGCGTCAAATCCAGTAGAATAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGATGATTGCAGCTGCTAATCAAAAACGATGGTGG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCAAACGGGCAAAAAGAAAAGCAGCTTTTTTG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GATATAATTGGGGCGCAAAAGAATACCGGAGGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTCCCTCCCGACTGTTACTTTTTAACCATTTACA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCGTGCCTACTGCAAGTGCCTATCCAGGTGGATTGCT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TGTCATTGGGAATTATAGTGGAAAAAATTAAGGGGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC

>NZ_CP020028|4|4|3346686-3348657|PILER-CR
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GAAGTCGGCTCCAATCTTCCATATGCCCACTACTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAATGTAAGTTTCAGATTTTTTTGGCTTCTCTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGCGACGCGAGAGTCTTCGAATATTTCTTTGATG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTCAACATCAAAAAAATATGTATGATCTATTTCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CACGAACGTTAGAGAGTTCCAAGTTTTCGGTGCT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAATTCAAGGTTACTGCCGTGGATACATGGGGTAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTATTGATGTGAAACAAAGTGCACATATGGTTGTTCGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTAATTTTGTCTTCTATTATCTCCCAACGTTTAGGAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	AAACGCTTGAAACTTAAAATACAAGAGCTTGAAGGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTACTTTTGCGCCGCTTAAACTGCGAGAATGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CACAACTACGTGAAACGTGGCCTTTTCTTTTGTAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	ATCGGTATGAGCCTCGTCCAAACAAATGATGGAT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GAAAGCACACTATTGCTTATTCCAACACGCTCAGCA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TAATTATTTTGTTTGGTATCGGAGTTTGAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GATATTCGATTCGCATGACAATGATCTCTTGATT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCCTGCAAAAGATGGTCATAGGCACCTCATTTTCAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCGAAGAAAAAGGGAAATATTTCGCTATGGTACTT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TAGTCCCGGTCGTCATAGACCTTGTCTCTACGAAAG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GCAAAAAGCGCCAATTGTACACCGTCAAGCGAGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CAAAAAGCGCCAATTGTACACCGTCAAGCGAGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	CATTGAATATCTGCGTCAAATCCAGTAGAATAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GGATGATTGCAGCTGCTAATCAAAAACGATGGTGG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTTTTGTTAATCATAGCACTCCAAACGGGCAAAAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCCAAACGGGCAAAAAGAAAAGCAGCTTTTTTG
ATTTCAATCCACGCACTCATATAGAGTGCGAC	GATATAATTGGGGCGCAAAAGAATACCGGAGGAA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TTCCCTCCCGACTGTTACTTTTTAACCATTTACA
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TCGTGCCTACTGCAAGTGCCTATCCAGGTGGATTGCT
ATTTCAATCCACGCACTCATATAGAGTGCGAC	TGTCATTGGGAATTATAGTGGAAAAAATTAAGGGGT
ATTTCAATCCACGCACTCATATAGAGTGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020028.1\|WP_007430135.1\|3350768_3351521_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP020028.1\|WP_094155403.1\|3343762_3346252_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP020028.1\|WP_094155397.1\|3338074_3338365_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP020028.1\|WP_094155401.1\|3340968_3342933_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP020028.1\|WP_094155406.1\|3351593_3353645_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274303
NZ_CP020028.1\|WP_167383761.1\|3354462_3354999_-\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP020028.1\|WP_094155395.1\|3333833_3334829_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP020028.1\|WP_007430129.1\|3359914_3360247_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094155409.1\|3355863_3359859_-\|type-VII-secretion-protein-EssC	unknown	unknown	gnl\|CDD\|274860
NZ_CP020028.1\|WP_094155404.1\|3348903_3349713_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP020028.1\|WP_094155398.1\|3338374_3339406_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP020028.1\|WP_094155399.1\|3339402_3340062_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP020028.1\|WP_094155408.1\|3355004_3355847_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_083837565.1\|3360639_3360879_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_007430133.1\|3353940_3354216_-\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP020028.1\|WP_094155400.1\|3340048_3340924_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP020028.1\|WP_094155396.1\|3334895_3335270_-\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP020028.1\|WP_007430139.1\|3335443_3335638_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020028.1\|WP_094155402.1\|3342929_3343649_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP020028.1\|WP_094155405.1\|3349919_3350756_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223704

Protein	Function_ID	Function_description	E-value
NZ_CP020028.1\|WP_007430135.1\|3350768_3351521_-\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	7.74466e-08
NZ_CP020028.1\|WP_094155403.1\|3343762_3346252_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	3.53036e-76
NZ_CP020028.1\|WP_094155405.1\|3349919_3350756_-\|hypothetical-protein	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	0.00105695
NZ_CP020028.1\|WP_094155401.1\|3340968_3342933_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	2.22684e-173
NZ_CP020028.1\|WP_094155406.1\|3351593_3353645_-\|hypothetical-protein	gnl\|CDD\|274303	TIGR02794, Protein_TolA, TolA protein. TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	2.07552e-10
NZ_CP020028.1\|WP_167383761.1\|3354462_3354999_-\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	2.48715e-05
NZ_CP020028.1\|WP_094155395.1\|3333833_3334829_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	9.7516e-115
NZ_CP020028.1\|WP_094155404.1\|3348903_3349713_-\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.05951e-88
NZ_CP020028.1\|WP_094155398.1\|3338374_3339406_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP020028.1\|WP_094155399.1\|3339402_3340062_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.31988e-27
NZ_CP020028.1\|WP_094155409.1\|3355863_3359859_-\|type-VII-secretion-protein-EssC	gnl\|CDD\|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP020028.1\|WP_007430133.1\|3353940_3354216_-\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	5.92216e-14
NZ_CP020028.1\|WP_094155400.1\|3340048_3340924_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	1.09552e-126
NZ_CP020028.1\|WP_094155396.1\|3334895_3335270_-\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	4.30763e-32
NZ_CP020028.1\|WP_094155402.1\|3342929_3343649_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.8465e-94
NZ_CP020028.1\|WP_094155397.1\|3338074_3338365_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.16279e-30

>NZ_CP020028.1|WP_094155403.1|3343762_3346252_-|CRISPR-associated-helicase/endonuclease-Cas3
MDYIAHIRESDHEIQTVADHLMETQQLAETYGDKIGIQHITGLAGMLHDLGKYTEKFQNYIRLAVQNPDIPPKRGSVDHSTAGGKLLYNLFHIQPQGPFDKQDFMNKALLSEVVGNAIISHHAYLQDFLDPDLESKFLDRVRDRKLEGFDHAVTLFYEQVMEESAFIHYVNQAGIELADYMKRDDNPDIELKMMFLSKFVFSALIDADRTNTRCFEEVNVKNEKNSNEPMIRQQLFQTYYERLMERITDLQSGENADTTINLLRKQMSEQCEQFAVKPSGIFTLSIPTGGGKTLASLRYALKHAVTFEKKHIIYVVPFTTIIEQNAQEVREIIRDDANLLEHHSNVVTNEVEDIDGEDHELEDVVVNTHQKLKLAKDNWDSPIIFTTMVQFLNVFYAGGSRNIRRLHNLSESVIIFDEVQKVPTHCTSLFNQALNFLKIYASSSIVLCTATQPELDFVHNKLDIDPDAEMVHDLDHVIEKFKRVEIVDKATDDTLDTEKLANFVEQKLADEPSILVILNTKAVVKNLYHRLTEGDGAIPIYHLSTSMCPAHRNRILGEVKTHLDHKEPVVCISTQLIEAGVDISFDCVIRSLAGLDSIAQAAGRCNRHGRDGTKQVYVIDHEEENLKDLKEIKIGKEITKKMFIDLKRDKTCYGGNILSGHAMEIYFQKYYTELASDLNYFIPKLRKNMTELLSVSRSENTYYRSYYDEHDTLLPLFLANSYKTAADHFQVIKDHTTAVIVPYGDGEKEGKEIIADLNGQQSIEDLSSLLRRAQQFTINITNTDKNQLSHNKALVSFLDGKIWALTDGAYDDSYGLNLQNDSSHGGFIL
>NZ_CP020028.1|WP_094155402.1|3342929_3343649_-|type-I-C-CRISPR-associated-protein-Cas5
MRNAIEFRVYGDYALFTDPLTKLGGEKLTYSVPTYQALKGIVESIYWKPTITMVVDKVRVLNAIRMESKGIRPIEYGGGNTLANYTYLKDPCYEVQAHFIFNLHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGEAPGFYDSYGDIHLGNMVHGINYPDETGRNHLEVRLWNPVMKDGVIEFIPPEICTQVRIIADMQPKQFDENNVQSADELFAEWEGWGMK
>NZ_CP020028.1|WP_094155401.1|3340968_3342933_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYESNLDRVGVIEKKHNDREYTLLPISHTTQNAQIEVEITEQGDFHSARVLDKDDFSTLIPCTEKSASRAGSVVAPYPLHDKLSYVAGDFVAYGGKIKKEEPFAAYIQQLEGWANSEYATPKLKSIYRYLSKRRLIKDLVDESILYLDEDQKLISKWEKKYERSPGEKPRIFTAVPGELESAFIRFNVYSPDKALTKVWQDKELYDSFIGYYSKLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFAHSHEAASISYEVSQKAHNALKWLIHRQGKTTMDNRVFLVWGNDATNVPSLTDNDNIFAMGFGTESSRPTAIKSHTNEELAFDLAKALSGYRNKLAVKADSKANVNILVLDSATTGRMAVLYYRNLDKKLYFDRLIDWHSKCAWLHRYQKDEQGELLLFWGAPATRDIAFAAYGPKANDKLIKGLMERMLPCIVDGRTIPQDIVRSATHRASNPVAMDKWEWEKTLSITCALINTREGYNVGLDEENTDRSYLFGRLLAIADVLERNALERSGQDKEKKRSTNAIRYMSVFSQHPERTWRTIQNALQPHQAKYGQSLNYYSIMIDEVASKIPFDQFNNEPLTGKYLLGFYSQRYKLYHNTDKKKHQANTTETNDSQNDNTPA
>NZ_CP020028.1|WP_094155400.1|3340048_3340924_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSILDHKIDFAVVLSVAKANPNGDPLNGNRPRQNYDGFGEISDVALKRKIRNRLQDMGESIFVQSNDRKSDSFSSLRERAEANPELGKIFKSKEGSSEEFARMACQEWMDVRSFGQVFAFKAVGKGAGVSVGVRGPVSIHTATSVLPIDITSMQITKSVNSEPGSEKGSDTMGMKHRVDFGVYVFKGSINTQLAEKTGFTNEDAAKIREALISLFENDVSSARPDGSMEVHKVYWWEHNSKLGKYSSAKVHRSLEVKPKENVNAADKSFDTHYECILTPLEGLEVQEYAGL
>NZ_CP020028.1|WP_094155399.1|3339402_3340062_-|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGIQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGDKLVVRALPVHSRELGITGICDVVEFVRDPLGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITASDRERVRASLQEMRHYFERNHTPKAKAGPHCQSCSLQHICVPEILNKKSVSSFIESRIAE
>NZ_CP020028.1|WP_094155398.1|3338374_3339406_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVVKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDDRRSARVARNMIIGKIYNHKWILERATRDHQLRIDMDRMKKVSASLTEIMKQVREVEELDILRGLEGTAAVQYNSVFDELILQQKDDFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRESLALDVMEELRGVYADRFVLSLINKKLIHGTGFYRKENGSVMMDDDTRKIVLKAWQERKQDKIIHPYLNEKMSWGLVPYSQALLLARHIRGDLDEYPPFLWK
>NZ_CP020028.1|WP_094155397.1|3338074_3338365_-|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSTQFRRLKYELEELIDKKEDSLRFYNLGDNYKKKVEHIGVKEAYDMESPLIL
>NZ_CP020028.1|WP_007430139.1|3335443_3335638_-|hypothetical-protein
MKKRNAVTPYGWKIKQKLVEKQMDQGTFCDTYHIPPSRLSNLIHGTRKAKKYRKLVSELLGLEE
>NZ_CP020028.1|WP_094155396.1|3334895_3335270_-|DUF1992-domain-containing-protein
MGMFFRMAEQKIAEAMAKGEFDHLPGAGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQQECVQMRDLLHACHEAGEQQRISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAVRKRLEE
>NZ_CP020028.1|WP_094155395.1|3333833_3334829_+|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQDQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYILRIEDIDMTRARSPLAQGIMEDLRWIGLEWDEGPDVGGPYGPYTQSQRLERFQAALDKLQGQDMLYPCFCSRADIVAAASAPHGLSGEGPAYSGTCRSLTPQEAETNSQHKLPSLRFKVPQNSDAVISFHDQVAGHAIFGAGDGGDFIVKRADGMFSYQLAVVVDDADMHITDVLRGYDLLDSTPRQLLLYQALGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGITPEAVIGWLAYFSGLLDSPEPVKAVDLVQDFHLDKLPKEPVILTEQFFRRLSDLQR
>NZ_CP020028.1|WP_094155404.1|3348903_3349713_-|SDR-family-oxidoreductase
MSYTSARSARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERILETEKEINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIIFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTVPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKSERLKQITIPVQFPEGGQPLANGPGQPGQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP020028.1|WP_094155405.1|3349919_3350756_-|hypothetical-protein
MNPLLSLLPASKRKGMNARLAQHFAYISSQTGDQPLSSHLSRFLCRYGYGRSAESASMGESGQDFAAVRIHKSVCCFVLCDGVGLSYRGDFAARYLGSSLLDWLEEGRDLSADQLRMHLERLASTATEELNRQPLGHESGLMRSVLEDKRRQGSQSMYICGRIELPKRGTRGRLRLAWQGDSRLRLWNGTEEISELFDHTFSTAERWSTSRGPIGGKPHWYERSIPADMAMRLQVYSDGLSDLDPIREPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP020028.1|WP_007430135.1|3350768_3351521_-|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMSMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHNTPLQDEHAVKLRNMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR
>NZ_CP020028.1|WP_094155406.1|3351593_3353645_-|hypothetical-protein
MSFQPNPGDELIINGTAYVVGRHPAAPGLAYAQAGRQGIVYQLNAKSGAPHEAKALKVFFPKFRIPAMVYQSEHMEAYGNIPGLQVCKRDVLTPERNGSLIAEQPDLLYAVLMPWIHGTTWFDCLTDQRQLEASDSLALARALAGIGSAMEQKGLAHCDLSAPNVMLPFFSEVELPEGTSAVELVDVEQMYSTKMDRPDALLAGSPGYAAHRTVHSGLWSAYADRFAGAIIIGEMLGWSDRVIVDKAWGESYFDQHEMQTPCERYFILRKSLETRWGSKVVELFSRAWDSQDLSSCPTFGEWLVVLNAITEQDIPVETEATELEAAETATSVEAAATESSSVETVSSWVAPPGTEQAAMLNHAAEEQGERGVTDKLFRQARELEQQNKPAAALEVYRSLYHFVEDGSPLHVEVSAAITGLEEQLNPKASEQPEKTPAWYRSKTFIVSTAAAVVLLAAGIPAVSILADQSNQRQIEAAKQEEAAKAAQAKLVAEQEAAYKALSEKQRQAAEEKARQQAKQQALAAQKQQEEQKKQQALIDQQVKYEAYLAQKDKDKQAAVKLAKQKAYDQQAKYEKYLAWKKDQKARAAQQEAARKATTEAEQKQKASMQARNKENVLQLITLYNKAYASQEGGSAAKAKSFANKFRALYDSNPSYYRSVGEVGYRASSIYNFLSDTNFRLPKI
>NZ_CP020028.1|WP_007430133.1|3353940_3354216_-|WXG100-family-type-VII-secretion-target
MAGRILITPEQVDQVANQFKQSGEQSQQIVSSLTQSISGMEGQWEGMTKQRFFQEFQEASKQMQAFVTTLNSISQELTAIANKFRTVDQAK
>NZ_CP020028.1|WP_167383761.1|3354462_3354999_-|WXG100-family-type-VII-secretion-target
MRIRVEPDVLRGLSGQLQHAAEQIQQLTAGLEQALQSVDWDVSARETVLNHWMQAKRMSEQIHAYLHTSGAQLNRKAEEFQAVDHDYHTILSLASQPLGRPVTMLDWSNQQSPSILPGQTSEGSDLISNPQSVVHAITGIPSSDAGTLNQDILEQATSSSPQDWYFTDPSVARDQPVA
>NZ_CP020028.1|WP_094155408.1|3355004_3355847_-|hypothetical-protein
MLTFQASKQKLITLKSKELFFLAGVLGSDRLLGVEDPFKGYLAEELTEEWEKVKAALLEKGYLKRVDKGKELAMPPTVFSRVAIAGLSNRACRIRYAREGKQFEGYLHCTNERVVELVKSVDEPDEYRLYDLGNVEKACETLIDKMGWVDRPLPESPALMFSKQAFNEIYKQSAGESVPLISSKLTEASGDAEGAAKLAQSLSSRVAEGELQLLVWNGREWESQRAAFVLCPAMSWIFRMSSNGNGDWLIAAMTSRNQFVDLLLNWLRQSAVTEEETEEG
>NZ_CP020028.1|WP_094155409.1|3355863_3359859_-|type-VII-secretion-protein-EssC
MNVLYQRSPRLRPALREEKLEILRPPAEPSKPSFSIISILIPLMMTLVTIGFYVYMSKTGKMGNSNYLMFQMITVVMMLTSYTIPFFVYLSNKKEYKRKLEERDRMYREQLQKHREELELKREEQIRTLYEIHGDPQICTQIVKNRNSSLWERSPEDEDFLQVRIGTGQVPFHIKLQIPRPDGYDRDPLLGAADELEEEFRLVDAASIALPLFQSKVVGLVGEREHTLAALRVILAQVAVRHSPDEVKIASFYDEREENEWVWMRWLPHVWDDDRTQRMMSDRSSSAHQLADFLFARLNRRKNNRSERHGKGMEIPCYVIVLSDSQLIEEEPLLPLLLEDGRAIDSCTIVLASRKEALPMQCQLIVEASKEQGVYARKSESAEVEQQSFKPDRLSKEEADALARYMAPIRLKRSSASDIPSVLPLFEMMSVADVEELDVTERWRRNRHPDTLPVPMGVRAGGKKIMINLHDKIERQGHGPHGLIAGTTGSGKSEVIQSIVASLAAEFHPHDLAFMLIDYKGGGMSNTFVNLPHVVGTITNLDNNLIERAKISLKAELVRRQKILNDAGNLQHIDEYYRLLRQRHEQPLPHLVIIIDEFAQLKRDQPEFMDELISIAAIGRTLGVHLILATQKPAGVVDDKIWSNSRFRICLRVQSEGDSRDMLKIPNAAWITKPGRGYFQVGSDEVFEEMQFAWSGAPYIGNSDISSALPVHEVRLNGKREALLTGGERASSGFKGEEAPKQLQIFIDYIANEAAKAGIERLQGPWLPPLPELLDLTHLRPSTKTDSASSPLELQALIGLVDDLPNQRQEPIYASLDHGHWAVYGMPGMGKTTFLQTLLMSTAQRFDANRWNGYIIDMGRTMRDFGELPQIGSVMMAEEDDRIKRLFRYLFKLVAVRKEMISEAGVKTISSYRRSAVEDVPQIVVAIDGYLNFRNAYPDENELLESLLREGGSLGITFIITANRITDVFEKFRSNIPNAVSFELSDPSDYYYAVGRPAKTPGLLIPGRALVKGHIPPLEFQTALPSPGGDEAERSTQLRRNIASIVQEWKGAHAPAILPLPERIPLAELLQQWDRTSGPSDALPYEVPVGLQSDDLEPFLLNLKEGPNFIVGSPMEGGKTSFLMSWILSLAYYTSPGQLEVYTLDTRYGGGGLSRLRHLPHVKAAAESEEEIGPLVQQVHDIVQQRSKDGNDPELLLVIDDADMLSKQLNDFMVKDQLSAIVRLGRDRNVHVVLSGVPSDFPTFGVDWFNDVKASQSGMLFGTLDSNDLSFFRIPYSEANAAAGGLKVLPPGQGYYVRRKFTRIKAAIPFSEQVSCEDWITKIRDRWHVVV
>NZ_CP020028.1|WP_007430129.1|3359914_3360247_-|hypothetical-protein
MILTVLSGRQETEWFDIEVADEYSVEHLKLMLGVRIFGEPPAEGMQYIMEAKFPEGLWFRVEDVQLLTGAGLREGCTVRIQRAFSTTQDEAPVYGRRSLFQNEKNGSIHT
>NZ_CP020028.1|WP_083837565.1|3360639_3360879_+|hypothetical-protein
MRTLITFQNKRIPVYINQENKQPVQKTLKLLSNTLENKISSGKRALKKCLNSLISIEIIGCEAILHSVSENDSLALSLY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020028_4	4.23\|3348125\|33\|NZ_CP020028\|CRISPRCasFinder,CRT,PILER-CR	3348125-3348157	33	NZ_CP034302	Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-3, complete sequence	68520-68552	5	0.848
NZ_CP020028_2	2.6\|1793142\|34\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793142-1793175	34	MK448885	Streptococcus phage Javan252, complete genome	4759-4792	8	0.765
NZ_CP020028_2	2.6\|1793142\|34\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793142-1793175	34	MK448721	Streptococcus phage Javan263, complete genome	6658-6691	8	0.765
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	522860-522894	8	0.771
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	522864-522898	8	0.771
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	522864-522898	8	0.771
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	522864-522898	8	0.771
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	522864-522898	8	0.771
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	522864-522898	8	0.771
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1650602-1650636	8	0.771
NZ_CP020028_4	4.23\|3348125\|33\|NZ_CP020028\|CRISPRCasFinder,CRT,PILER-CR	3348125-3348157	33	KU878088	Bacillus phage AR9, complete genome	105197-105229	8	0.758
NZ_CP020028_4	4.23\|3348125\|33\|NZ_CP020028\|CRISPRCasFinder,CRT,PILER-CR	3348125-3348157	33	MF360957	Bacillus virus PBS1, complete genome	15500-15532	8	0.758
NZ_CP020028_1	1.13\|336158\|34\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	336158-336191	34	NZ_CP018188	Streptococcus salivarius strain ICDC2 plasmid, complete sequence	155335-155368	9	0.735
NZ_CP020028_1	1.15\|336289\|33\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	336289-336321	33	MN694210	Marine virus AFVG_250M185, complete genome	30405-30437	9	0.727
NZ_CP020028_2	2.15\|1793745\|35\|NZ_CP020028\|PILER-CR,CRISPRCasFinder,CRT	1793745-1793779	35	HQ634193	Cyanophage P-RSM6 genomic sequence	82109-82143	9	0.743
NZ_CP020028_4	4.6\|3346982\|34\|NZ_CP020028\|CRISPRCasFinder,CRT,PILER-CR	3346982-3347015	34	MN270258	Streptococcus phage phi-SgaBSJ27_rum, complete genome	75810-75843	9	0.735
NZ_CP020028_4	4.6\|3346982\|34\|NZ_CP020028\|CRISPRCasFinder,CRT,PILER-CR	3346982-3347015	34	MN270259	Streptococcus phage phi-SgaBSJ31_rum, complete genome	75846-75879	9	0.735
NZ_CP020028_4	4.5\|3346916\|34\|NZ_CP020028\|CRISPRCasFinder,CRT,PILER-CR	3346916-3346949	34	MN693529	Marine virus AFVG_25M294, complete genome	37978-38011	11	0.676

1. spacer 4.23|3348125|33|NZ_CP020028|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034302 (Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-3, complete sequence) position: , mismatch: 5, identity: 0.848

cattgaatatctgcgtcaaatccagtagaataa	CRISPR spacer
cattggatatctccgtcaaatccagtagataat	Protospacer
*****.****** ****************  *

2. spacer 2.6|1793142|34|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to MK448885 (Streptococcus phage Javan252, complete genome) position: , mismatch: 8, identity: 0.765

gtttcatccaaatctttccacctcctcacataaa	CRISPR spacer
gtttcatctaaatctttccaactcttaaaagatg	Protospacer
********.*********** ***.* * * * .

3. spacer 2.6|1793142|34|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to MK448721 (Streptococcus phage Javan263, complete genome) position: , mismatch: 8, identity: 0.765

gtttcatccaaatctttccacctcctcacataaa	CRISPR spacer
gtttcatctaaatctttccaactcttaaaagatg	Protospacer
********.*********** ***.* * * * .

4. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.771

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
acagcagctacaacagcagctacaacagcggtggt	Protospacer
************.******.*****   *  ***

5. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.771

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
acagcagctacaacagcagctacaacagcggtggt	Protospacer
************.******.*****   *  ***

6. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.771

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
acagcagctacaacagcagctacaacagcggtggt	Protospacer
************.******.*****   *  ***

7. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.771

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
acagcagctacaacagcagctacaacagcggtggt	Protospacer
************.******.*****   *  ***

8. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.771

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
acagcagctacaacagcagctacaacagcggtggt	Protospacer
************.******.*****   *  ***

9. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.771

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
acagcagctacaacagcagctacaacagcggtggt	Protospacer
************.******.*****   *  ***

10. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 8, identity: 0.771

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
acagcagctacaacagcagctacaacagcggtggt	Protospacer
************.******.*****   *  ***

11. spacer 4.23|3348125|33|NZ_CP020028|CRISPRCasFinder,CRT,PILER-CR matches to KU878088 (Bacillus phage AR9, complete genome) position: , mismatch: 8, identity: 0.758

cattgaatatctgcgtcaaatccagtagaataa	CRISPR spacer
ccttcaatatctgcgtctaatccagtttcaaca	Protospacer
* ** ************ ********   *  *

12. spacer 4.23|3348125|33|NZ_CP020028|CRISPRCasFinder,CRT,PILER-CR matches to MF360957 (Bacillus virus PBS1, complete genome) position: , mismatch: 8, identity: 0.758

cattgaatatctgcgtcaaatccagtagaataa	CRISPR spacer
ccttcaatatctgcgtctaatccagtttcaaca	Protospacer
* ** ************ ********   *  *

13. spacer 1.13|336158|34|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018188 (Streptococcus salivarius strain ICDC2 plasmid, complete sequence) position: , mismatch: 9, identity: 0.735

ctgtatgaaaaaaggatgatattattgtgttcaa	CRISPR spacer
ttatccgagaaaaggataatattattgtgtcaat	Protospacer
.*.* .**.********.************. *

14. spacer 1.15|336289|33|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to MN694210 (Marine virus AFVG_250M185, complete genome) position: , mismatch: 9, identity: 0.727

aagtgaaaaatgtcaagtggaatagcgtagaac	CRISPR spacer
aagtgaaaaatgtcaggtggagtatctcatggg	Protospacer
***************.*****.** * .* ..

15. spacer 2.15|1793745|35|NZ_CP020028|PILER-CR,CRISPRCasFinder,CRT matches to HQ634193 (Cyanophage P-RSM6 genomic sequence) position: , mismatch: 9, identity: 0.743

acagcagctacagcagcagttacaagtcctttggg	CRISPR spacer
gtagcagcaacagcagcagttccaagtccaagagt	Protospacer
..****** ************ *******   .*

16. spacer 4.6|3346982|34|NZ_CP020028|CRISPRCasFinder,CRT,PILER-CR matches to MN270258 (Streptococcus phage phi-SgaBSJ27_rum, complete genome) position: , mismatch: 9, identity: 0.735

cacgaacgttagagagttccaagttttcggtgct	CRISPR spacer
aatgaacgttccagagttccaagttttagacgag	Protospacer
 *.*******  *************** *..*

17. spacer 4.6|3346982|34|NZ_CP020028|CRISPRCasFinder,CRT,PILER-CR matches to MN270259 (Streptococcus phage phi-SgaBSJ31_rum, complete genome) position: , mismatch: 9, identity: 0.735

cacgaacgttagagagttccaagttttcggtgct	CRISPR spacer
aatgaacgttccagagttccaagttttagacgag	Protospacer
 *.*******  *************** *..*

18. spacer 4.5|3346916|34|NZ_CP020028|CRISPRCasFinder,CRT,PILER-CR matches to MN693529 (Marine virus AFVG_25M294, complete genome) position: , mismatch: 11, identity: 0.676

ttcaacatcaaaaaaatatgtatgatctatttca	CRISPR spacer
agatacatcaagaaaatatgtaggatctttaatt	Protospacer
    *******.********** ***** *  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2281290 : 2288426

Staphylococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094154695.1\|2281290_2281956_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.9e-39	40.5
WP_094154696.1\|2282017_2282701_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.2e-60	57.2
WP_007430874.1\|2282732_2283197_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.8e-42	61.2
WP_094154697.1\|2283370_2284165_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.9e-08	30.5
WP_094154698.1\|2284133_2284742_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.6e-14	31.7
WP_094154699.1\|2284876_2285578_+	DUF2953 domain-containing protein	NA	NA	NA	NA
WP_094154700.1\|2285663_2286155_+	sporulation protein YtfJ	NA	NA	NA	NA
WP_094154701.1\|2286242_2286968_-	protein-glutamine gamma-glutamyltransferase	NA	NA	NA	NA
WP_094154702.1\|2287163_2288426_+	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	3.9e-07	31.3

DBSCAN-SWA_2

4094540 : 4129319

Brevibacillus_phage(88.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094155854.1\|4094540_4095563_-	sigma-70 family RNA polymerase sigma factor	A0A0K2CPD8	Brevibacillus_phage	2.8e-101	58.0
WP_007429438.1\|4095586_4095934_-	hypothetical protein	NA	NA	NA	NA
WP_094155855.1\|4095999_4096335_-	hypothetical protein	A0A0K2CPQ6	Brevibacillus_phage	2.9e-34	58.7
WP_094155856.1\|4096373_4096826_-	hypothetical protein	A0A0K2CPR2	Brevibacillus_phage	3.7e-37	51.4
WP_043890851.1\|4096994_4097531_-	sigma-70 family RNA polymerase sigma factor	A0A0K2CPD2	Brevibacillus_phage	7.8e-42	52.1
WP_094157032.1\|4098445_4102450_-	DNRLRE domain-containing protein	A0A0K2CP88	Brevibacillus_phage	1.4e-42	27.1
WP_094155857.1\|4102486_4105291_-	filamentous hemagglutinin	A0A127AW61	Bacillus_phage	1.3e-15	35.7
WP_094155858.1\|4105275_4105893_-	hypothetical protein	A0A0K2CP89	Brevibacillus_phage	2.7e-54	52.5
WP_010349351.1\|4105929_4106424_-	hypothetical protein	A0A127AW38	Bacillus_phage	3.3e-39	54.9
WP_094155859.1\|4106683_4107904_-	hypothetical protein	A0A0K2CP47	Brevibacillus_phage	1.8e-09	70.8
WP_094155860.1\|4108010_4108844_-	hypothetical protein	A0A0K2CPK2	Brevibacillus_phage	4.3e-79	54.9
WP_094157033.1\|4108858_4109983_-	cell adhesion protein	A0A0K2CPP1	Brevibacillus_phage	3.4e-140	63.6
WP_094155861.1\|4109958_4113519_-	hypothetical protein	A0A0K2CP84	Brevibacillus_phage	2.0e-29	23.0
WP_094155862.1\|4113549_4115385_-	hypothetical protein	A0A0K2CNY7	Brevibacillus_phage	2.8e-256	70.1
WP_094155863.1\|4115422_4116847_-	hypothetical protein	A0A0K2CP42	Brevibacillus_phage	6.4e-192	66.2
WP_094155864.1\|4116886_4119205_-	hypothetical protein	A0A0K2CPJ7	Brevibacillus_phage	7.1e-241	52.5
WP_025682897.1\|4119222_4119609_-	hypothetical protein	A0A0K2CPN7	Brevibacillus_phage	8.6e-51	69.5
WP_007429422.1\|4119612_4120032_-	hypothetical protein	A0A0K2CP80	Brevibacillus_phage	5.5e-35	54.7
WP_094155865.1\|4120146_4123638_-	peptidoglycan DD-metalloendopeptidase family protein	A0A0K2CNY2	Brevibacillus_phage	0.0e+00	55.4
WP_094155866.1\|4123649_4124699_-	hypothetical protein	A0A0K2CP35	Brevibacillus_phage	2.6e-102	49.6
WP_094155867.1\|4124700_4125318_-	S-layer homology domain-containing protein	A0A0K2CPJ2	Brevibacillus_phage	9.2e-79	68.0
WP_094155868.1\|4125373_4126165_-	hypothetical protein	A0A0K2CPN3	Brevibacillus_phage	8.3e-24	46.0
WP_094155869.1\|4126230_4126449_-	hypothetical protein	A0A0K2CP74	Brevibacillus_phage	1.7e-11	47.9
WP_094155870.1\|4126574_4127009_-	DNA polymerase III subunit gamma/tau	A0A0K2CPC8	Brevibacillus_phage	5.3e-49	65.6
WP_094155871.1\|4127031_4128084_-	hypothetical protein	A0A0K2CNX7	Brevibacillus_phage	2.2e-141	73.6
WP_007429414.1\|4128210_4128468_-	hypothetical protein	NA	NA	NA	NA
WP_094155872.1\|4128620_4129319_-	queuosine precursor transporter	A0A2H4J2N7	uncultured_Caudovirales_phage	6.0e-10	33.8

DBSCAN-SWA_3

4348116 : 4359929

Bacillus_phage(50.0%)

portal,tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094156012.1\|4348116_4348908_-	DUF2313 domain-containing protein	S6BFJ0	Thermus_phage	1.2e-22	42.0
WP_094156013.1\|4348965_4349277_-	hypothetical protein	NA	NA	NA	NA
WP_094156014.1\|4349336_4349948_-	hypothetical protein	NA	NA	NA	NA
WP_094156015.1\|4349960_4352522_-	hypothetical protein	R4JDZ8	Bacillus_phage	3.7e-25	32.4
WP_094157044.1\|4352523_4353093_-	YmfQ family protein	A0A0A7RTU9	Clostridium_phage	2.6e-27	42.5
WP_094156016.1\|4353139_4354291_-\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	1.6e-39	34.4
WP_094156017.1\|4354290_4354761_-	DUF2634 domain-containing protein	A0A0N7ACH4	Bacillus_phage	9.9e-25	37.9
WP_094156018.1\|4354747_4355155_-	hypothetical protein	A0A0N7ACD3	Bacillus_phage	9.5e-08	30.7
WP_094156019.1\|4355147_4356128_-\|portal	phage portal protein	A0A0N6W8H4	Bacillus_phage	5.9e-80	48.8
WP_167383809.1\|4356124_4356763_-	LysM peptidoglycan-binding domain-containing protein	A0A0N7ACF7	Bacillus_phage	1.3e-40	46.2
WP_094156021.1\|4356802_4358836_-	hypothetical protein	NA	NA	NA	NA
WP_094156022.1\|4359017_4359452_-	hypothetical protein	A0A2H4J883	uncultured_Caudovirales_phage	1.6e-21	42.8
WP_094156023.1\|4359521_4359929_-\|tail	phage tail tube protein	A0A2H4J032	uncultured_Caudovirales_phage	9.4e-40	58.0

DBSCAN-SWA_4

4634173 : 4697907

Bacillus_phage(14.29%)

coat,portal,integrase,terminase,transposase

attL 4685549:4685564|attR 4701500:4701515

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094156211.1\|4634173_4635022_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	E9P639	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	4.4e-23	27.5
WP_094156212.1\|4635227_4635869_-	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	3.4e-20	36.6
WP_094156213.1\|4635865_4636489_-	deoxynucleoside kinase	Q5ULP7	Lactobacillus_virus	8.2e-19	33.5
WP_094156214.1\|4636661_4637261_-	response regulator transcription factor	NA	NA	NA	NA
WP_094156215.1\|4637257_4638391_-	sensor histidine kinase	NA	NA	NA	NA
WP_094156216.1\|4638473_4639529_-	fatty acid desaturase	A0A1V0SAL5	Catovirus	5.3e-34	32.1
WP_094156217.1\|4639952_4640819_+	bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase	NA	NA	NA	NA
WP_094156218.1\|4640815_4641451_+	cyclodeaminase/cyclohydrolase family protein	NA	NA	NA	NA
WP_094156219.1\|4641685_4643200_+	copper amine oxidase	NA	NA	NA	NA
WP_094156220.1\|4643330_4644323_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094156221.1\|4644532_4644925_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_094156222.1\|4645073_4645748_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_094156223.1\|4645865_4648799_-	peptidase m28	NA	NA	NA	NA
WP_094157055.1\|4649212_4649920_-	hypothetical protein	NA	NA	NA	NA
WP_167383770.1\|4650127_4650427_+	DUF3953 domain-containing protein	NA	NA	NA	NA
WP_007428914.1\|4650526_4651894_-	amino acid permease	NA	NA	NA	NA
WP_094156225.1\|4652384_4653149_+	glucose 1-dehydrogenase	A0A0N9R355	Chrysochromulina_ericina_virus	4.7e-08	22.9
WP_094156226.1\|4653315_4653762_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_094156227.1\|4653828_4654305_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_094156228.1\|4654485_4655361_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_094156229.1\|4655531_4656212_+	hypothetical protein	NA	NA	NA	NA
WP_094156230.1\|4656208_4657624_+	hypothetical protein	NA	NA	NA	NA
WP_094156231.1\|4657636_4658920_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_094157056.1\|4658934_4659447_+	hypothetical protein	NA	NA	NA	NA
WP_007428906.1\|4659451_4659868_+	DUF4280 domain-containing protein	NA	NA	NA	NA
WP_094156232.1\|4660003_4661482_-	YdiU family protein	A0A075BSJ0	Microcystis_phage	3.1e-48	32.9
WP_094156233.1\|4661674_4662544_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_094156234.1\|4662728_4663223_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_094156235.1\|4663341_4664208_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_094156236.1\|4664251_4664887_-	5,6-dimethylbenzimidazole synthase	NA	NA	NA	NA
WP_094156237.1\|4665148_4665799_-	hypothetical protein	NA	NA	NA	NA
WP_094156238.1\|4666226_4666805_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_094156239.1\|4666953_4668111_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_094156240.1\|4671599_4672124_+	hypothetical protein	NA	NA	NA	NA
WP_094156241.1\|4673215_4673512_-	hypothetical protein	NA	NA	NA	NA
WP_094156242.1\|4673747_4674281_-	cupin domain-containing protein	Q2I8C5	Bacillus_phage	3.0e-62	70.8
WP_094156243.1\|4675782_4676901_-	serine hydrolase	NA	NA	NA	NA
WP_157739782.1\|4676911_4677139_-	hypothetical protein	NA	NA	NA	NA
WP_094156244.1\|4677595_4678468_-	AraC family transcriptional regulator	D0R0F8	Streptococcus_phage	1.0e-38	35.4
WP_167383771.1\|4678613_4678775_-	hypothetical protein	NA	NA	NA	NA
WP_094156245.1\|4679140_4679926_+	hypothetical protein	NA	NA	NA	NA
WP_094156246.1\|4684068_4684698_+	hypothetical protein	NA	NA	NA	NA
WP_094156247.1\|4685132_4685420_+	hypothetical protein	NA	NA	NA	NA
WP_094156248.1\|4685449_4687072_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	8.0e-106	45.9
4685549:4685564	attL	NA	NA	NA	NA
WP_094156249.1\|4687350_4688502_-	hypothetical protein	NA	NA	NA	NA
WP_094156250.1\|4688498_4688789_-	hypothetical protein	NA	NA	NA	NA
WP_094156251.1\|4688788_4689100_-	DNA-packaging protein	NA	NA	NA	NA
WP_094156252.1\|4689092_4689311_-	hypothetical protein	NA	NA	NA	NA
WP_094156253.1\|4689408_4690239_-\|coat	P22 coat protein - protein 5 domain protein	A0A1L2JY55	Aeribacillus_phage	2.6e-76	51.6
WP_094156254.1\|4690266_4690884_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_094156256.1\|4691661_4692969_-\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	4.4e-54	31.7
WP_094157057.1\|4693104_4693365_-	hypothetical protein	NA	NA	NA	NA
WP_094156257.1\|4693437_4694286_-	copper amine oxidase N-terminal domain-containing protein	NA	NA	NA	NA
WP_094156258.1\|4694431_4695982_-\|terminase	phage terminase large subunit	A0A0N7AEF1	Bacillus_phage	3.8e-73	33.5
WP_094156259.1\|4696158_4697004_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	3.9e-11	27.4
WP_094156260.1\|4697169_4697907_-\|transposase	transposase	A0A2H4JAE2	uncultured_Caudovirales_phage	2.0e-19	39.3
4701500:4701515	attR	NA	NA	NA	NA

DBSCAN-SWA_5

4753988 : 4765646

Prochlorococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094156298.1\|4753988_4755536_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	7.7e-74	52.6
WP_094156299.1\|4755642_4756257_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.1e-21	35.3
WP_094156300.1\|4756256_4757297_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.0e-70	46.1
WP_094156301.1\|4757498_4757921_+	hypothetical protein	NA	NA	NA	NA
WP_094156302.1\|4757949_4759431_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.7e-52	31.8
WP_094156303.1\|4759415_4761659_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.8e-164	42.3
WP_007428838.1\|4761636_4762326_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_014279841.1\|4762330_4762576_-	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	1.4e-06	37.7
WP_094156304.1\|4762637_4763519_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	1.3e-41	34.9
WP_094156305.1\|4763533_4764250_-	hypothetical protein	NA	NA	NA	NA
WP_007428833.1\|4764347_4765646_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	4.1e-20	33.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020028

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection