CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020017	Tetragenococcus halophilus strain KUD23, complete genome	2 crisprs	RT,DEDDh,cas3,cas14j,csa3,DinG,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6	0	9	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020017_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020017_1

1512921-1513010

Orphan

Consensus_repeat	Method
ATTCTTCCCCCATGCGGAAGGTGTAGAG	CRISPRCasFinder

1 spacers

RT,csa3

The CRISPR arrays of NZ_CP020017_1

>merge|NZ_CP020017|1|1512921-1513010|CRISPRCasFinder
ATTCTTCCCCCATGCGGAAGGTGTAGAGTTCATTTGTGTAATAAGTCAGGTTTTTTATCAAAATTCTTCCCCCATGCGGAAGGTGTAGAG

>NZ_CP020017|1|1|1512921-1513010|CRISPRCasFinder
ATTCTTCCCCCATGCGGAAGGTGTAGAG	TTCATTTGTGTAATAAGTCAGGTTTTTTATCAAA
ATTCTTCCCCCATGCGGAAGGTGTAGAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020017.1\|WP_014123482.1\|1503087_1503444_-\|reverse-transcriptase	unknown	unknown	gnl\|CDD\|275209
NZ_CP020017.1\|WP_061840860.1\|1520119_1520710_-\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153234
NZ_CP020017.1\|WP_061840867.1\|1513116_1513815_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293840
NZ_CP020017.1\|WP_061840859.1\|1521054_1522914_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319774
NZ_CP020017.1\|WP_155982957.1\|1512471_1512669_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020017.1\|WP_081497521.1\|1501791_1502895_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP020017.1\|WP_061840858.1\|1522991_1523222_+\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|238219
NZ_CP020017.1\|WP_041591783.1\|1507806_1508004_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270357
NZ_CP020017.1\|WP_014124333.1\|1506330_1507350_-\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122
NZ_CP020017.1\|WP_014124329.1\|1509000_1509483_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP020017.1\|WP_094243738.1\|1518232_1519438_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP020017.1\|WP_061840865.1\|1514434_1515256_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP020017.1\|WP_061840863.1\|1515867_1516560_-\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP020017.1\|WP_069029372.1\|1516677_1518036_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP020017.1\|WP_014124330.1\|1508439_1508970_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|225695
NZ_CP020017.1\|WP_061840861.1\|1519750_1519948_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|377256
NZ_CP020017.1\|WP_014124334.1\|1504938_1506267_-\|aminopeptidase-C	unknown	unknown	gnl\|CDD\|367314
NZ_CP020017.1\|WP_014123943.1\|1503497_1504358_-\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NZ_CP020017.1\|WP_094243737.1\|1514003_1514423_-\|DUF2000-domain-containing-protein	unknown	unknown	gnl\|CDD\|378176
NZ_CP020017.1\|WP_014124328.1\|1509555_1510737_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225139

Protein	Function_ID	Function_description	E-value
NZ_CP020017.1\|WP_014123482.1\|1503087_1503444_-\|reverse-transcriptase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	7.51219e-11
NZ_CP020017.1\|WP_061840860.1\|1520119_1520710_-\|glutamine-amidotransferase	gnl\|CDD\|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	2.60541e-67
NZ_CP020017.1\|WP_061840867.1\|1513116_1513815_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.20872e-18
NZ_CP020017.1\|WP_061840859.1\|1521054_1522914_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319774	cd02079, P-type_ATPase_HM, P-type heavy metal-transporting ATPase. Heavy metal-transporting ATPases (Type IB ATPases) transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. These ATPases include mammalian copper-transporting ATPases, ATP7A and ATP7B, Bacillus subtilis CadA which transports cadmium, zinc and cobalt out of the cell, Bacillus subtilis ZosA/PfeT which transports copper, and perhaps also zinc and ferrous iron, Archaeoglobus fulgidus CopA and CopB, Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase, and Escherichia coli ZntA which is selective for Pb(2+), Zn(2+), and Cd(2+). The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This family belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP020017.1\|WP_081497521.1\|1501791_1502895_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.29451e-68
NZ_CP020017.1\|WP_061840858.1\|1522991_1523222_+\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|238219	cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. In the case of copper, stoichiometry of binding is one Cu+ ion per binding domain. Repeats of the HMA domain in copper chaperone has been associated with Menkes/Wilson disease due to binding of multiple copper ions.	4.31483e-11
NZ_CP020017.1\|WP_041591783.1\|1507806_1508004_-\|hypothetical-protein	gnl\|CDD\|270357	cd13639, PBP2_OpuAC_like, Substrate binding domain of Lactococcus lactis ABC-type transporter OpuA and related proteins; the type 2 periplasmic binding protein fold. This subfamily is part of a high affinity multicomponent binding-protein-dependent transport system specific to betaine compounds for osmoregulation. The periplasmic substrate-binding domain, which is often fused to the permease component of the ATP-binding cassette transporter complex, is involved in uptake of osmoprotectants (also termed compatible solutes) such as glycine betaine and proline betaine. Many microorganisms accumulate these compatible solutes in response to high osmolarity to offset the loss of cell water. This domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0.000287502
NZ_CP020017.1\|WP_014124333.1\|1506330_1507350_-\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	3.5254e-39
NZ_CP020017.1\|WP_014124329.1\|1509000_1509483_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.96919e-18
NZ_CP020017.1\|WP_094243738.1\|1518232_1519438_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	5.2261e-140
NZ_CP020017.1\|WP_061840865.1\|1514434_1515256_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.51875e-28
NZ_CP020017.1\|WP_061840863.1\|1515867_1516560_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	7.16518e-16
NZ_CP020017.1\|WP_069029372.1\|1516677_1518036_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.22141e-42
NZ_CP020017.1\|WP_014124330.1\|1508439_1508970_+\|N-acetyltransferase	gnl\|CDD\|225695	COG3153, COG3153, Predicted acetyltransferase [General function prediction only].	3.12728e-53
NZ_CP020017.1\|WP_061840861.1\|1519750_1519948_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|377256	pfam04237, YjbR, YjbR. YjbR has a CyaY-like fold.	2.88675e-08
NZ_CP020017.1\|WP_014124334.1\|1504938_1506267_-\|aminopeptidase-C	gnl\|CDD\|367314	pfam03051, Peptidase_C1_2, Peptidase C1-like family. This family is closely related to the Peptidase_C1 family pfam00112, containing several prokaryotic and eukaryotic aminopeptidases and bleomycin hydrolases.	0
NZ_CP020017.1\|WP_014123943.1\|1503497_1504358_-\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.5038e-127
NZ_CP020017.1\|WP_094243737.1\|1514003_1514423_-\|DUF2000-domain-containing-protein	gnl\|CDD\|378176	pfam09391, DUF2000, Protein of unknown function (DUF2000). This is a family of proteins of unknown function. The structure of one of the proteins in this family has been shown to adopt an alpha beta fold.	9.00676e-61
NZ_CP020017.1\|WP_014124328.1\|1509555_1510737_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	2.48031e-121

>NZ_CP020017.1|WP_155982957.1|1512471_1512669_+|hypothetical-protein
MSIPRIESFLEKFINHSGSLSFLSHQVLLLLDPLLNSLLVDSEEMGKEEFIQQTTEILLYGMTKG
>NZ_CP020017.1|WP_014124328.1|1509555_1510737_-|class-I-SAM-dependent-methyltransferase
MLEKKTYDKLLGHAFDIPVKVEYWDGTSEVYGEGTPETVIQLKKAIPIKELTSLPTLTLGEAYMNGDIEVKGDLQELVASAYRSVNSFVTDNSGFLKFLPKISHSEKNSKEDVQSHYDIGNDFYRLWLDKTMTYSCAYFKDENDTLEQAQKNKVRHVLTKLNPERGKTLVDIGCGWGSVLFMAAEEFGLKATGITLSQEQYDQVKEEIKTRGLEGQVDVYLEDYREVEEKFDYATSIGMFEHVGKENLPKYFEQVQKLLVPNGRALIHGITGQHEGVGSDPFLSKYIFPGGYIPNVAENLTNIMNAGLQLTDLEPLRRHYQKTLEIWYQNYLEHIDTVVDRYGEPFSRMWSLYLQACAASFEAGNIDVMQYLLVNGTSGYGLPMTREYMYKNS
>NZ_CP020017.1|WP_014124329.1|1509000_1509483_+|GNAT-family-N-acetyltransferase
MAIKIISAYDYPYEIKKLFNEYTNMLITQDKQINNYLAMQNYSDELENLEKKYGLPDGRLYLAYYNSKLAGCIGLKKLDNHYCEIKRFYVRPAFRRKHIGTHLMDTIIEESRQIGYQHILLDTLPHLKAAIVNYKKHGFYEIESYNDNPIGNSIYMQLDL
>NZ_CP020017.1|WP_014124330.1|1508439_1508970_+|N-acetyltransferase
MVTLKTIEHSDYQTVDSLIRKAFTNTEEGYGNEAELAANLRKDATYQNYLEIVALKDNTIVGHGLLSEVDVYEDSNLLSTGLCLAPLAVLPEMQKQGIGAMLLEELEIRAKKENYPFISILGHPAYYSKFGYQLASHFNIQAPFPVPDDAYFVKELYPASLKNVQGTICYLDAFNE
>NZ_CP020017.1|WP_041591783.1|1507806_1508004_-|hypothetical-protein
MNKLKKSLIFGLSPIFLLAACDNGETENATEAQGDVNYSEEVDYTITGIEPGAGITEVSYDTIDS
>NZ_CP020017.1|WP_014124333.1|1506330_1507350_-|acyltransferase-family-protein
MAEKKRDPYFDNAKFLLMILVVFGHMMQPFIENEQWNHDLYYTIFAFHMPAFIFISGFFAKSFDPQKKAPVATNFQKFIVPYIFFQWLYSLFNRLSGAEEHFTFQLDVPNWSLWFLISSFFWQISLYFFRRIRPTAGITISILISLLVGYTPFIGRELTLQRTAVFLPFFIIGYYLPKGFFDWFKNFKYKKLFAVGFVIIYALVNYLNEVNKYMFFGSKPYDDFLNFPEWGFLVRIVTFMLAIIGMLAFFSLVPTRETSYTKEGKYTLIAYLLHGFFIRGMRAFDLENIHLGFPGFIVLALASILLTTVLASEPVGKVYNKIERYFLGNKNKTKPTYNG
>NZ_CP020017.1|WP_014124334.1|1504938_1506267_-|aminopeptidase-C
MAEITNELTAKFAAEFKENDKQQVAQNAVVKNGITNSAENIVAQSNNVPVFSIDLKTGNVSNQKQSGRCWMFAALNTFRHKILDNFDLKDFELSQNYTNFWDKYEKSNYFYENILATADQEVTSRKVAFLLETPQQDGGQWDMMVSLFNKYGVVPKAAMPESSNSSNSRDLNNYLNKKLRKDAATLRQLVADGASANDIQASREDMLQEVYNILAISLGTPPTTFAFEYRDENKEYHIDRDLTPKSFYDKYVGVDLNNYVPIINAPTDDKPYNQSYTVEMLGNVVGGKQVKYLNLDMDTFKKLAIAQLEQGESVWFGCDVGQSSNRQNGIMSLDTYDMNELFDVDFTTTKAQRLDYGESLMTHAMVLTGVDIVDDKSTKWKVENSWGDKVGDKGFFVASDAWMDEYTYQIVVRKDLLTAEQLKAYEKEPTVLAPWDPMGALA
>NZ_CP020017.1|WP_014123943.1|1503497_1504358_-|group-II-intron-reverse-transcriptase/maturase
MMNQSGFPLMNELVSSMNIDRAIEKVKKNKGAPGIDDMTVSEIKSHLNKYRRPFVQKLREGTYRPQPTKRVEIPKGNGKKRKLSIPVVRDRVVQQMILQVITPLIDPTFSENSYGFRPGKSCQQAIAKAGQYYEEGYDVVVDCDLKSYFDTINHQKLMHRMQWYIEEKAVLQLIWNFLNAGVMEGEILRPTSKGASQGSPLSPLLANVYLDQLDKELERRNHRFIRYADDFIIFVQSERAAQRVQESITQFLEKKLRLTVNQEKSQIIKAHQLEYLSYRMRKDKGK
>NZ_CP020017.1|WP_014123482.1|1503087_1503444_-|reverse-transcriptase
MTNRKRVGTLDEMIKTINQYTQGWIQYYKDGELKTFLAKQMEYLRHRLRALIWKRWKKVDTKYRQLKARGASHKEAMTYANSRKQYWRISKSKLLNRIFSKEKFKQWKLKDFIEILEK
>NZ_CP020017.1|WP_081497521.1|1501791_1502895_+|MFS-transporter
MYYVQPIGTQVVESFQVSTSSIGSVTMLTQVGYALGLLFIVPLGDVLNKRRLIISMAALSSLSLLGAFFAPNFQLFILAAFIIGLLSVVPQIIIPYGAVLAGPEKRGQVMGKLLSGLLVGILLSRTFSGVVASFLPWRSIYLIAPLLIILLTVLLTFKMPKDPVKNATLSYMDSLKSIPLLIKKQRVLCEAAVSGFFMFGTFSIFWSTLIFYISSPIYNWGTFEAGILAIFGLAGAVAAPLVGKLSDQYAQRTIVWMGIIMQTVSFIILHFFAAHILPLILSIILLDIGNQFGQVANQTRVQNLGEQVSNRNNTVFMFSYFIGGALGSFLGTTMWGQAGWVGVTLTALSFQLLAMIFHFVVFKKQDQ
>NZ_CP020017.1|WP_061840867.1|1513116_1513815_+|MBL-fold-metallo-hydrolase
MELRQLTDRIFYYPHQTETDRPMLAYVQGDKLSLAIDAGNSSDHVAEFYQTLQAKKLKLPDLTAMTHWHWDHTFGMQQIHGLSIAHTKTNQLLQIEKEKIQDKKYVQSLKLENPFLAKEFSDDKTIEIVPSDIQFENKLSVLLGNLTAQIFHTESPHSSDSTLVYIPEEKILFLGDATSEDFENDGYMDQEKLKSLIKVIEQTDCTYCMLGHAQPLGKIELVDYLKSINSLS
>NZ_CP020017.1|WP_094243737.1|1514003_1514423_-|DUF2000-domain-containing-protein
MSAENKCVILIDDALSLGLVANTAAILGMSLGKKHPELIGPDTLDGDQFLHSGIIYIPVPILKSNRKNLFDLRNRLYQKDYQNIETVDFTNLAQSCKTYEEYMDRFQQMKATDLQYMGIGLYGPKKIINKLTGNLSLLK
>NZ_CP020017.1|WP_061840865.1|1514434_1515256_-|AraC-family-transcriptional-regulator
MSKDFREIYFDKQLKLEGYYFEGVSQSFPNHFHDYYVIGFVEKGKRNLTCNTLEYEVNPGDFLLFNPFDSHGCTQVEALDLTYRAINVSIERMREIITTITGKEELVKFTKPILKLPKIDELFLLLHQLILENKDDLNREELLYFFIDALIAHAADIKIEEIAFSEASKENLLLAKSYLEKNFASTVSLEELSRRCHLNKYTLIRYFTKYFGVTPYQYLQTIRIKEAKELLSNGKELLSISLKVGFSDQSHFTRVFKSLIGITPKQYQGIFKQ
>NZ_CP020017.1|WP_061840863.1|1515867_1516560_-|winged-helix-turn-helix-transcriptional-regulator
MSIYKNFYSTSALFGHPTRMAILVALSDGKALPAGEIAKMVKVSPQTTSEHLAKLMKAGFLNQQKSGKYRYYYIANPKVAEVVEGMLALSPEIEVCSMRDSLDKKALSYARTCYGYLAGNLGIQLTKAMINLDYIKDLGNSSLLTQKGYAWTQEFGLTSTKKFLTQTIPYHVDWTERKFHIAGPFALQLTKKLLTLQWLEEGTIHRSVRVTPQGHQGFVDEFGFKPAEKE
>NZ_CP020017.1|WP_069029372.1|1516677_1518036_+|MFS-transporter
MNDKKPQLSHALTFVACMGMFLSTLDTGIMNVALPFFTHFFNTHENIAAMSVVGYTVSLAAVIMPLGSLSDRIGKLKISFFGFLLFGISSLLCGLAPNILFLIIFRVFQGIGAAALQATSSALITSYVKKEQLNKALGTLGIAIGLGPVLGPSIGGMFLSLGAWQWIFWINIPLVLVTLFVNLFLLKQIKSSPVKIHSFDYKGTSLCLTAIVLLLSGLNFIVEPSQLALGTIFILGAIIVFIMLIKVEKKQKNPLFHLQDYRKSKIALDLLETALLGFATSMIFLLPPFLLEQLLHISSGKTGLYVLGAPIGLVVFSKISGNLNDGTKHRQFVRIGLWTMFISFLLLALTSQLWTPILVTSLLFIYGAGAGSFQPANIALIMQSSSQKMQSEVGSLQRMIQNIGIAISTTVGSGILILPFSLRTNLTIGWGLTTSLLFITLFTHLFIKRAKK
>NZ_CP020017.1|WP_094243738.1|1518232_1519438_+|IS256-family-transposase
MTQLNININFEELTEAIMQSDMNMMMKSLAVTVLNAYMEVERDEFIQAQNYERNDQRLDYRNGYYERNFTLAVGKLRLKIPRTRSGEFSTQVFEQYQRKDQAFVLSLMEAVINGVSTKKVTRIVEELCGESVSKSFVSNTMKRLDPEIEAFKSRSLTYSSFRYVYVDAMYIKVRENHHVVSKGVYIAQGVNQKNRREILGFKVSEEESYASWKQFFQELRERGLTQPRLIISDAHAGLKKAVQEIFTGTAWQRCTVHFLRNMIDQMPKKNSAGARQYLKKIFRSSTLQEAKEARQKFEEYVQEDTRYEAVLAQLDQGFWDGLQYLSEPEDYHISLRTTNSLERLNREIRRREKVVSIFPNSVSAERLIGAVLMDIQEEWQKGPKPFLKGPIVDEEETSFTD
>NZ_CP020017.1|WP_061840861.1|1519750_1519948_-|MmcQ/YjbR-family-DNA-binding-protein
MKGKEELGITDIKLNSALLELLVMKDEFLPAYLMDKKYWVTILLSEVSVGELFALIEDSFYMIKV
>NZ_CP020017.1|WP_061840860.1|1520119_1520710_-|glutamine-amidotransferase
MKQAIVFLLDEYADWEPSYIASILNSDTTWNVKTASIKPKVTSIGGFQVDVDYLIENIPQNIDLLVLIGGNSWEITNSSIVKLVTYHLKQGNIVSAICGAVDFLAQNGLLEGYKHTGNTQFLWTDFESYTNAADFCEEQAVRDRNLITANGTAPLEFSQLCLEAVRFDEPKEITKTIDLYKMGYYGYVEKYGDPFS
>NZ_CP020017.1|WP_061840859.1|1521054_1522914_+|cadmium-translocating-P-type-ATPase
MKLQQWIMQHKNHLTLINGLLILLAGVSKFLFTWIFGYQLAMLIASVIGMLPIFLQAYQALRVKVISIDLLVSVAILGALLIGEYNESAIVAFLFLFGSFLEQKTLEKTRTAIHSLTQMAPKSALKITDNGRTESVDIDDIDKGDHLLVKTDAQVPVDGVIDEGEGYLNEASVTGESQQRKKEKGDDVFAGTFLDNGTLKIVTKRVGEDTTFGKIIELVEEAQDSKSNAERFIDKFAKYYTPAVLLLAFIVGIFSQDVRLAITILVLGCPGALVIGVPVSNVAGIGSGAKSGILIKGGEVIDKFSKVDTFVFDKTGTLTMGKPSVAAVKNYTDNFTESLKITASIERESDHPLGQAIVDYANVSSYVSVEQTNVVKGQGIIATLSDKKVLIGNQSLMVDHHVPLSKSIKKDIHQLQSTGHSLVMVAMNGRLSLLIGIKDQIRPGAKETLAHLKQTGVKELIMLTGDNQETAENIAQELGITKVYGNLLPENKADYIRQLQKEGHQVAFVGDGVNDSPSLALSDVGIAMGGGTEVAIETSDVVLIQSNFERIAKAYHLTKKIALNMQENIMIALATVLLLLIGLIFGYIYMASGMFVHELSILIVIFNGMRLLLGTKKKA
>NZ_CP020017.1|WP_061840858.1|1522991_1523222_+|heavy-metal-associated-domain-containing-protein
MEKVILQLGTLTCPSCMQKIEQAVKKENGVEKVKVLFNASKVKVEINPALTNAEALKKTIEKVGYKVENTKTKELS

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Crispr_ID: NZ_CP020017_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020017_2

1866889-1869507

TypeIII

Consensus_repeat	Method
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	CRISPRCasFinder
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	CRT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	PILER-CR

36 spacers

cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6

The CRISPR arrays of NZ_CP020017_2

>merge|NZ_CP020017|2|1866889-1869507|CRISPRCasFinder,CRT,PILER-CR
TTCTCAGTCCCCTAATGATGGAGTTAGGTATCTATTTGATAACTGGCAACGAATTAAAGCAAAGCAACACATAGGTTCTCGCCCCCTAATAGTGGGATTAGGTATCTATTGTTTTTCCAATAGCTGCAATTTCATTTTGGTTTCGTTCTCGTCTCCTAATGATGGAGTTGGACATTTATTCAAAGCTACCCAGTATTATATTATTTAAAGAAGCCGTTATCGTCCCCTAATGATGGGGTTAGGTATCTATTATGATAAATATAAAAACGGCACTTTGAAAATTGAAGTTCTCGTCCCCTAATGATGGGGTTAGGTATCTATTCGATAAATGAAATCTTAAATGCTTCTTCTGCTCTAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTTATATAGGGCTTTACCATATGGACGAATACACGGCTAAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAGAAGATCCAAGCGCCAACTATAACTTAGACGACCGGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTGGTATTAGATCATGAGGGGATTGTTTTACCTGAAACAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTTATTTGCTTGGTCCTCTTTCTATCTAAACATATTTTAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAAATTGAAGAATCTGACACTGTGGAACTTGGCATGCAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAAAAATAGATGATATCAACAGAATCCACATGATTGAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTACTAGTAAAAGAAAATTTTCAAGAAAGATCAGGAAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTTTTTATTATGGGGTTATCTATTTATATAAGAAAGGGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAAGAGCAAAAGAATAAACAAAAATTTGAAGACTTCTTGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTGACAAGGAAGAGCAAGTCTATTTAGAAGACATAGAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAGGAAGTTTAGATGAGAAAACACAAAAGAAAATTGGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAAATATAAGAAAATGATGAAGTATGAAAAGTATTTTGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTACACTTGAGTAACAAAATATTATAAATAAATTTCTTGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAGAAAAAAGAAAATAATAAGAAAAGTTGTTGACAGGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTACAGATCAGGGCTAAAGAGCTATGCCCTGGTATAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTACTTTATCGTTTTTTGGTATTTCGGCGGTGTACCAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAAGTAAGCAAATTAGAAAATGGTAGCCTGGTACACGGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTTCTATTAGTCTAGTACACCGGAAACCACATAGCTTGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAATATTAAAACAACTACTTTTGATCAACTAGAAAATTGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAAATAAAATAATTGTTTATTCCACGGCACCTGTAAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTCTTAGAACTCTTATATACAGCGGTGGGGATCACTGGAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTATTTAAGCAAAAAAATACTTTACATCTTAGTAAATGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTGACAAGTCCATTTACTGCCAGTGGCTGCAAAGCAAAAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTAAAGAAATAGAGAAAGCTATTTCGAATGTTTATGGGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTGGTTTTGACGATATTTACGAAGATATGATCGTTGGCGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTGAATTACTAGAACTAATGCAAAAGGCAAAAGAAAACGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTTCACTACTACAATAGGGAACTACCAGAAAGCTATGGGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTATAATAAACAGGAGGCATAGAATGAGAAAGCACAAAAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTGTCGTAGATACCGTTATCGACTATTTGGACGACAACGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTTGACGGCATGAACGAAAAGCAGAAAGAAATATATGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATTTAATAGATACCGTCATCGACTACTTAGACGACAAGTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT

>NZ_CP020017|2|2|1866889-1869507|CRISPRCasFinder
TTCTCAGTCCCCTAATGATGGAGTTAGGTATCTATT	TGATAACTGGCAACGAATTAAAGCAAAGCAACACATAG
GTTCTCGCCCCCTAATAGTGGGATTAGGTATCTATT	GTTTTTCCAATAGCTGCAATTTCATTTTGGTTTC
GTTCTCGTCTCCTAATGATGGAGTTGGACATTTATT	CAAAGCTACCCAGTATTATATTATTTAAAGAAGCC
GTTATCGTCCCCTAATGATGGGGTTAGGTATCTATT	ATGATAAATATAAAAACGGCACTTTGAAAATTGAA
GTTCTCGTCCCCTAATGATGGGGTTAGGTATCTATT	CGATAAATGAAATCTTAAATGCTTCTTCTGCTCTA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TATATAGGGCTTTACCATATGGACGAATACACGGCTAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGAAGATCCAAGCGCCAACTATAACTTAGACGACCG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GGTATTAGATCATGAGGGGATTGTTTTACCTGAAACA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TATTTGCTTGGTCCTCTTTCTATCTAAACATATTTTA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATTGAAGAATCTGACACTGTGGAACTTGGCATGCA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAAAATAGATGATATCAACAGAATCCACATGATTGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACTAGTAAAAGAAAATTTTCAAGAAAGATCAGGAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TTTTATTATGGGGTTATCTATTTATATAAGAAAGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAGAGCAAAAGAATAAACAAAAATTTGAAGACTTCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GACAAGGAAGAGCAAGTCTATTTAGAAGACATAGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGGAAGTTTAGATGAGAAAACACAAAAGAAAATTG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATATAAGAAAATGATGAAGTATGAAAAGTATTTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACACTTGAGTAACAAAATATTATAAATAAATTTCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGAAAAAAGAAAATAATAAGAAAAGTTGTTGACAG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACAGATCAGGGCTAAAGAGCTATGCCCTGGTATA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACTTTATCGTTTTTTGGTATTTCGGCGGTGTACCA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAGTAAGCAAATTAGAAAATGGTAGCCTGGTACACG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TCTATTAGTCTAGTACACCGGAAACCACATAGCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AATATTAAAACAACTACTTTTGATCAACTAGAAAATT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATAAAATAATTGTTTATTCCACGGCACCTGTAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	CTTAGAACTCTTATATACAGCGGTGGGGATCACTGGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ATTTAAGCAAAAAAATACTTTACATCTTAGTAAAT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GACAAGTCCATTTACTGCCAGTGGCTGCAAAGCAAAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAAGAAATAGAGAAAGCTATTTCGAATGTTTATGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GGTTTTGACGATATTTACGAAGATATGATCGTTGGC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GAATTACTAGAACTAATGCAAAAGGCAAAAGAAAAC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TCACTACTACAATAGGGAACTACCAGAAAGCTATGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ATAATAAACAGGAGGCATAGAATGAGAAAGCACAAAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GTCGTAGATACCGTTATCGACTATTTGGACGACAAC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TGACGGCATGAACGAAAAGCAGAAAGAAATATAT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TAATAGATACCGTCATCGACTACTTAGACGACAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT

>NZ_CP020017|2|1|1866889-1869507|CRT
TTCTCAGTCCCCTAATGATGGAGTTAGGTATCTATT	TGATAACTGGCAACGAATTAAAGCAAAGCAACACATAG
GTTCTCGCCCCCTAATAGTGGGATTAGGTATCTATT	GTTTTTCCAATAGCTGCAATTTCATTTTGGTTTC
GTTCTCGTCTCCTAATGATGGAGTTGGACATTTATT	CAAAGCTACCCAGTATTATATTATTTAAAGAAGCC
GTTATCGTCCCCTAATGATGGGGTTAGGTATCTATT	ATGATAAATATAAAAACGGCACTTTGAAAATTGAA
GTTCTCGTCCCCTAATGATGGGGTTAGGTATCTATT	CGATAAATGAAATCTTAAATGCTTCTTCTGCTCTA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TATATAGGGCTTTACCATATGGACGAATACACGGCTAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGAAGATCCAAGCGCCAACTATAACTTAGACGACCG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GGTATTAGATCATGAGGGGATTGTTTTACCTGAAACA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TATTTGCTTGGTCCTCTTTCTATCTAAACATATTTTA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATTGAAGAATCTGACACTGTGGAACTTGGCATGCA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAAAATAGATGATATCAACAGAATCCACATGATTGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACTAGTAAAAGAAAATTTTCAAGAAAGATCAGGAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TTTTATTATGGGGTTATCTATTTATATAAGAAAGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAGAGCAAAAGAATAAACAAAAATTTGAAGACTTCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GACAAGGAAGAGCAAGTCTATTTAGAAGACATAGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGGAAGTTTAGATGAGAAAACACAAAAGAAAATTG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATATAAGAAAATGATGAAGTATGAAAAGTATTTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACACTTGAGTAACAAAATATTATAAATAAATTTCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGAAAAAAGAAAATAATAAGAAAAGTTGTTGACAG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACAGATCAGGGCTAAAGAGCTATGCCCTGGTATA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACTTTATCGTTTTTTGGTATTTCGGCGGTGTACCA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAGTAAGCAAATTAGAAAATGGTAGCCTGGTACACG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TCTATTAGTCTAGTACACCGGAAACCACATAGCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AATATTAAAACAACTACTTTTGATCAACTAGAAAATT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATAAAATAATTGTTTATTCCACGGCACCTGTAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	CTTAGAACTCTTATATACAGCGGTGGGGATCACTGGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ATTTAAGCAAAAAAATACTTTACATCTTAGTAAAT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GACAAGTCCATTTACTGCCAGTGGCTGCAAAGCAAAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAAGAAATAGAGAAAGCTATTTCGAATGTTTATGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GGTTTTGACGATATTTACGAAGATATGATCGTTGGC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GAATTACTAGAACTAATGCAAAAGGCAAAAGAAAAC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TCACTACTACAATAGGGAACTACCAGAAAGCTATGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ATAATAAACAGGAGGCATAGAATGAGAAAGCACAAAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GTCGTAGATACCGTTATCGACTATTTGGACGACAAC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TGACGGCATGAACGAAAAGCAGAAAGAAATATAT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TAATAGATACCGTCATCGACTACTTAGACGACAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT

>NZ_CP020017|2|1|1867104-1869507|PILER-CR
GTTATCGTCCCCTAATGATGGGGTTAGGTATCTATT	ATGATAAATATAAAAACGGCACTTTGAAAATTGAA
GTTCTCGTCCCCTAATGATGGGGTTAGGTATCTATT	CGATAAATGAAATCTTAAATGCTTCTTCTGCTCTA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TATATAGGGCTTTACCATATGGACGAATACACGGCTAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGAAGATCCAAGCGCCAACTATAACTTAGACGACCG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GGTATTAGATCATGAGGGGATTGTTTTACCTGAAACA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TATTTGCTTGGTCCTCTTTCTATCTAAACATATTTTA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATTGAAGAATCTGACACTGTGGAACTTGGCATGCA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAAAATAGATGATATCAACAGAATCCACATGATTGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACTAGTAAAAGAAAATTTTCAAGAAAGATCAGGAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TTTTATTATGGGGTTATCTATTTATATAAGAAAGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAGAGCAAAAGAATAAACAAAAATTTGAAGACTTCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GACAAGGAAGAGCAAGTCTATTTAGAAGACATAGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGGAAGTTTAGATGAGAAAACACAAAAGAAAATTG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATATAAGAAAATGATGAAGTATGAAAAGTATTTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACACTTGAGTAACAAAATATTATAAATAAATTTCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AGAAAAAAGAAAATAATAAGAAAAGTTGTTGACAG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACAGATCAGGGCTAAAGAGCTATGCCCTGGTATA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ACTTTATCGTTTTTTGGTATTTCGGCGGTGTACCA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAGTAAGCAAATTAGAAAATGGTAGCCTGGTACACG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TCTATTAGTCTAGTACACCGGAAACCACATAGCTT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AATATTAAAACAACTACTTTTGATCAACTAGAAAATT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAATAAAATAATTGTTTATTCCACGGCACCTGTAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	CTTAGAACTCTTATATACAGCGGTGGGGATCACTGGA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ATTTAAGCAAAAAAATACTTTACATCTTAGTAAAT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GACAAGTCCATTTACTGCCAGTGGCTGCAAAGCAAAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	AAAGAAATAGAGAAAGCTATTTCGAATGTTTATGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GGTTTTGACGATATTTACGAAGATATGATCGTTGGC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GAATTACTAGAACTAATGCAAAAGGCAAAAGAAAAC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TCACTACTACAATAGGGAACTACCAGAAAGCTATGG
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	ATAATAAACAGGAGGCATAGAATGAGAAAGCACAAAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	GTCGTAGATACCGTTATCGACTATTTGGACGACAAC
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TGACGGCATGAACGAAAAGCAGAAAGAAATATAT
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT	TAATAGATACCGTCATCGACTACTTAGACGACAA
GTTCTCGTCCCCTAATAATGGGGTTAGGTATCTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020017.1\|WP_094243903.1\|1862200_1862407_-\|transposase	unknown	unknown	gnl\|CDD\|379154
NZ_CP020017.1\|WP_094243909.1\|1870901_1871915_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl\|CDD\|224251
NZ_CP020017.1\|WP_094243905.1\|1863954_1864413_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP020017.1\|WP_094243899.1\|1858051_1859095_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|143390
NZ_CP020017.1\|WP_155224385.1\|1863331_1863904_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020017.1\|WP_094243910.1\|1871932_1872829_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NZ_CP020017.1\|WP_094243907.1\|1865938_1866847_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP020017.1\|WP_094243902.1\|1861255_1862116_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375609
NZ_CP020017.1\|WP_069028648.1\|1872825_1873500_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP020017.1\|WP_094243908.1\|1869652_1870900_-\|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|187830
NZ_CP020017.1\|WP_094243900.1\|1859105_1860782_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238760
NZ_CP020017.1\|WP_094243915.1\|1878727_1879672_-\|acetamidase/formamidase-family-protein	unknown	unknown	gnl\|CDD\|225279
NZ_CP020017.1\|WP_094243898.1\|1856448_1857399_-\|acetamidase/formamidase-family-protein	unknown	unknown	gnl\|CDD\|225279
NZ_CP020017.1\|WP_069028647.1\|1873511_1873940_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NZ_CP020017.1\|WP_094243912.1\|1876229_1876976_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl\|CDD\|227838
NZ_CP020017.1\|WP_094243913.1\|1877333_1877594_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020017.1\|WP_094243901.1\|1860778_1861117_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131309
NZ_CP020017.1\|WP_094243916.1\|1879831_1880743_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020017.1\|WP_094243911.1\|1873948_1876237_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP020017.1\|WP_094243906.1\|1864884_1865211_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775

Protein	Function_ID	Function_description	E-value
NZ_CP020017.1\|WP_094243903.1\|1862200_1862407_-\|transposase	gnl\|CDD\|379154	pfam13384, HTH_23, Homeodomain-like domain.	2.42415e-06
NZ_CP020017.1\|WP_094243909.1\|1870901_1871915_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	6.76167e-18
NZ_CP020017.1\|WP_094243905.1\|1863954_1864413_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	3.88248e-37
NZ_CP020017.1\|WP_094243899.1\|1858051_1859095_+\|hypothetical-protein	gnl\|CDD\|143390	cd05400, NT_2-5OAS_ClassI-CCAase, Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme. In vertebrates, 2-5OASs are induced by interferon during the innate immune response to protect against RNA virus infections. In the presence of an RNA activator, 2-5OASs catalyze the oligomerization of ATP into 2-5A. 2-5A activates endoribonuclease L, which leads to degradation of the viral RNA. 2-5OASs are also implicated in cell growth control, differentiation, and apoptosis. This family includes human OAS1, -2, -3, and OASL. CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This class I group includes the archaeal Sulfolobus shibatae and Archeoglobus fulgidus CCA-adding enzymes. It belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this family.	1.18934e-08
NZ_CP020017.1\|WP_094243910.1\|1871932_1872829_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	1.78698e-34
NZ_CP020017.1\|WP_094243907.1\|1865938_1866847_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.43998e-90
NZ_CP020017.1\|WP_094243902.1\|1861255_1862116_+\|hypothetical-protein	gnl\|CDD\|375609	pfam18179, SUa-2TM, SMODS- and Ubiquitin system-associated 2TM effector domain. Predicted pore-forming effector domain observed exclusively in conserved genome contexts with the SMODS nucleotide synthetases and the bacterial Ubiquitin conjugation systems.	2.07412e-31
NZ_CP020017.1\|WP_069028648.1\|1872825_1873500_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.30428e-80
NZ_CP020017.1\|WP_094243908.1\|1869652_1870900_-\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	4.3004e-74
NZ_CP020017.1\|WP_094243900.1\|1859105_1860782_+\|hypothetical-protein	gnl\|CDD\|238760	cd01483, E1_enzyme_family, Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common reaction mechanism catalyzed by MoeB, ThiF and the E1 enzymes begins with a nucleophilic attack of the C-terminal carboxylate of MoaD, ThiS and ubiquitin, respectively, on the alpha-phosphate of an ATP molecule bound at the active site of the activating enzymes, leading to the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD and ThiS.	1.64947e-13
NZ_CP020017.1\|WP_094243915.1\|1878727_1879672_-\|acetamidase/formamidase-family-protein	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	1.22428e-98
NZ_CP020017.1\|WP_094243898.1\|1856448_1857399_-\|acetamidase/formamidase-family-protein	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	2.80743e-101
NZ_CP020017.1\|WP_069028647.1\|1873511_1873940_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	2.50374e-23
NZ_CP020017.1\|WP_094243912.1\|1876229_1876976_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	3.49921e-14
NZ_CP020017.1\|WP_094243901.1\|1860778_1861117_+\|hypothetical-protein	gnl\|CDD\|131309	TIGR02256, Uncharacterized_protein_y4qB, integrative and conjugative element protein, VC0181 family. This uncharacterized protein is found in several Proteobacteria, among them Rhizobium sp. NGR234, Vibrio cholerae, Myxococcus xanthus, and E. coli strain ECOR31. In the latter, it is part of an integrative and conjugative element that is readily induced to excise and circularize.	3.02547e-22
NZ_CP020017.1\|WP_094243911.1\|1873948_1876237_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NZ_CP020017.1\|WP_094243906.1\|1864884_1865211_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	6.21712e-15

>NZ_CP020017.1|WP_094243907.1|1865938_1866847_-|type-II-CRISPR-associated-endonuclease-Cas1
MRDCIYVEHQNFVSVVTNSFKFVNVVSKETTYIPFSEVECLIFENELSYFSKKLVSKCMEENIALLFCDKKHSPVTMLTNDFGHSNRLKRLNLQMSLGNKVKKRLWRKIVIGKINNQAVNLQLLTENNDMGKMLVLASKQVDEGDTKNREAYAARRYFTNLFGPNFKRGRYDDVVNASLNYGYALIRAMIRREIAIHGLEASVGIHHQSIENAFNLSDDLIEPFRPFVDSYVYENIFNEGALILELGEKKALLNILLENCIIDEKVCTVTDAIKVAVTSFVNCLDKNSSSPLKLPSFIEVGK
>NZ_CP020017.1|WP_094243906.1|1864884_1865211_+|helix-turn-helix-transcriptional-regulator
MKLSQLDKVGPHVAAYRNKAGLTQQQLATETGLSPQFIGFIENGNRNISLQTLIKITNVFGIDIITFLSPFEQQDENLGQLIQKIEHSSKKDSYIQMFNNILDTADNE
>NZ_CP020017.1|WP_094243905.1|1863954_1864413_-|PTS-sugar-transporter-subunit-IIA
MFDFSFLPELIISNLTVNSKEEVITYLSKLLEDSRLVERNYKNDVLLREKEFPTGLPVKNGAIAIPHAKSTHVFNNGVAVGTLKNPVYFNSMEDSNLEIPVDMVMLLAISESDKQLKMLQAIMRLLSNEEIIDTLKNKKGSKDIAKQFTKLI
>NZ_CP020017.1|WP_155224385.1|1863331_1863904_+|hypothetical-protein
MIIFRFTFIILKIEKKERLKNGNFFGVLGLFLPMLISFFGNQSKAIKAAEIEMSKRIIELSENQIEFNMDDAIKIIKSVSFEKEIDVTKVRQRFERAGHIAFDKINIRKHTDFLAGLLTVMEKMPGLPDKIKLYDIIAFVSEIATCIISFVWIFSNTSTLYISIPLSMIAGCQVGVLLNNFSNLLKKRIV
>NZ_CP020017.1|WP_094243903.1|1862200_1862407_-|transposase
MTQRYNQETRELVLQLNEQGQSVPSLAREYGISEATIYNWKKAYTPDEETGKSQADIHQMEKEMHRLK
>NZ_CP020017.1|WP_094243902.1|1861255_1862116_+|hypothetical-protein
MKTKFVFVKFVLPFLLIIASIGVPIIFFNPNSTVLGLNILLKNEKEANSVVQILEGLNLKATYLISLFALITLLNYLKKQNSDKLFNSDSNIYYNFWYPCFWFASNVLGYKKIQLAGIPLYLQFKLVLRGTFPIIVPDIYEEHYDIPKKIKNKEQEIVSVSYITSSNSSGTQKSVNLIISDTYYITDKEIDSEYINLPTIRVTSNFINNRRYLNNELVQKVRESIEEIKDKHYEEIYVYTTANPHNNLNIINSSFRFFGRFINAKIYIMQKGKKRNSPYIEKKQII
>NZ_CP020017.1|WP_094243901.1|1860778_1861117_+|hypothetical-protein
MKQFHNIVTTVEFKDNVVNLLTEYVQNTYETPESEGVLMGKRLFDGSIIITDITKPQKSDRWGRSHFKKDGKIHQKISDKIWQNSGGYIMYLGEWHTHPEPFPSPSFIDLKG
>NZ_CP020017.1|WP_094243900.1|1859105_1860782_+|hypothetical-protein
MVNLEHLKEYLENISYFSDSVITGDYIGTNQKRIKLKIVFPYHFPVVLPKIYVINLDELNLFIPHLEYDGLICYTPSNNVIFDRSNTEVITIIALKKAIKTLEDGIQGVNESEFRKEFIAFWDRQKNLQPIIFFASANDEIKTLEIFENNKDIIINDDVLKNKEAMYRFFPTNTEKSDSMDTLYLPLRSKNKVLPPNPRKGWTKKKLLNIVRKNCTQAKKAYFDKWINKKNDKGKLLILKIPISENNEVLIGYWLNATKQSIKKYTGPISPLYVRRFDFTYLLERTSGEHSFTNLNICIVGVGSVGSKLSNELANLGVAKMTLIDPEKFEADNLFRHELGVDGIKYGKPKLKVEVLQQDLEKKNPYLEVAVESMDILDIISSDPNYFDQFDYSFICIGDTMHSLEINRFFSKSNNKVFYSWVEPLGIGGHVLYIDYCKKGCFQCLNTDPNTGNIISNRSSLVKPGQTIEKTLASCRSAFVPYSSLTSREAAVKTVELFHKIVYKEITKNSVLTWLGDFKNFKDIGYQFSDRFTKNKNYFPTVESNFINNKCEICGVKP
>NZ_CP020017.1|WP_094243899.1|1858051_1859095_+|hypothetical-protein
MVDLQKNFITFHDKIKLEYEDNSLLRDYKDQVLDGLKKNLDIDHQFSPFVQGSYSVFTGIKSSDVDIDFDIDIGIELDINRNDYEDPVKLKVFVRDAMKLTFPQSKVEIKKPCVTINFSDKNSGESVHVDIALYAKENGSYYLARGNEYGNYENRYWEEAEPKKLKDKINNFSEDPDARKQFRRCIRYLKRWKDNKFNQENRPTGIGITSLALQNFKSKKSVDLFAGSTTYNDLQALKEFVSILTKSFTCPAYDEKNGTNYMRIEADLPVSPHSDTFCKMTAKQMKDFKIKLDSLYEDLNYAGDTFDKHEATKLLNKQFGNDFEIVSEQNVSEQSRNNGFITDYPSA
>NZ_CP020017.1|WP_094243898.1|1856448_1857399_-|acetamidase/formamidase-family-protein
MAETHKCTTDTVHYTWHKEHEPILTIDSGDTVVFETREVSDNQFNFQSTTEAISELDWDYVYPLSGPVYINGAEPGDTLAVEILDLKTKHWGWTAVLPGLGLLAEDYPDAYLRTFDLSDGKYIHFSDDIKVPIEPFLGTMGVCPKDGDGTPIMPPGNFGGNLDVRQLTIGTKLYLPVQQAGALFSCGDGHAAQGDGEVCVSALECPMYASLKFTVIKASEKSIPSPQFQTKGGLTQKVNHDDFYGTTGVGPDLMTGAQEALRAMIDYVSETYNIEKIDAYLLASLCVDLKISEIVDAGQYVVSALLPLSIFNDSQE
>NZ_CP020017.1|WP_094243908.1|1869652_1870900_-|type-III-A-CRISPR-associated-protein-Csm6
MQTLISCVGDTDPIRNYHDGPLLHIARGIRPEKIVIVHSERSQEKHDNIVKALHSIPDYHPEIVVDERIIKNDDIFLFDKMFEVLSKIIQEYARSEEEIILNLTSATPQIISAMFSINRISGLNVRAYQVATPSNTSNEGIKHNNQQDIQQLIESNKDNRKDYNNRLIEDKAEKFQQLLVRKTFLDLIREYDYEGAVQVISGNDLMLSKKKKGKLHHELDNLIKSIKTQNLLPEVENSEFDVSQKTILNAYLLISLQAKRELNTEVLIRVKNFAEFIVEMYLDKNYNGLIVRYDGKPYLNIEGFEDVVLKLRYSLKKAGNELNTDRYLSLPLYAEIIRIIQPDSSLLKLIDKVNGVNTFRNQVAHGFKSINMKNSRVKDLAETCWMLLLIVNDVDEKWRSYFEDKNKVFKEMVGY
>NZ_CP020017.1|WP_094243909.1|1870901_1871915_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MEKRKRYELTLRTMAPLHIGSGTTYTQKEYIYENGYYYFPDMGILYKKLQKQEEKKARIFEDFLMKNGHTNSRRPRLVQFLNDQQIRERNFSGYQIKETGFELEKKKSARGNLNEISAFVKDAYGCPYIPGSSLKGAIRTILVNEYFRRDDIPWGPKQQDIFHQIRVSDSEPINIDQLILAQKWDFSPKKLTARSLPIHRESLRPMSVATFIITAVGEQAIELMDQLPQFAKEYYQKYTNQFLSDFPSRYIQKYFWSPLYLGAGSGFWTKTNIDKADNSRHKKGGKMAMKGKGVLKLTKAPITKFRLNGKPRQLIENSENLYEMGKCVFNLKERGEN
>NZ_CP020017.1|WP_094243910.1|1871932_1872829_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MTLKIYKMKFQHAHFGEGVLSESASSFDASRLYSALFLEAKKMDVVDEFMKLTQNANFVLSDAFPFIDDQPFLPKPIGYPKVEQDNADDNLKKVRQTAKKLKKIFYLPLNQLELFLKQQANIEELAEYQAQLAEHSYTTQKGVDPFEVGVTVYNSALYVLASQSPLFDQLMDSLQYSGVGGKRSSGLGQYSLEILSLPDELAENLTTNKQQRVMALSTCLPMNQEMLTCLDGANYLLKKSSGFAYSETAGALLRKQDLYKFKAGSTFQTSFTGDIVDVRPDNFPHPVWNFAKGIFYQL
>NZ_CP020017.1|WP_069028648.1|1872825_1873500_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MSQFTKIKIEGKIELLSGLHIGGSTAFAAIGAVDSPVIKDPVNNLPMIPGSSIKGKIRFLLAQAMNQKVAEDPNQDDSKITRLFGASMGGGEKGDQIIRGRLLFRDSLLTNKAVLDELGVRTYTETKFENTIDRRTAEASPRQIERAIRGSQFSFELIYELDNQEEAEEDFETILTGLQLLELDYLGGNGSRGYGRVCFKDIAANTVYGKYDATQFNERLKELL
>NZ_CP020017.1|WP_069028647.1|1873511_1873940_-|type-III-A-CRISPR-associated-protein-Csm2
MNHGKSRQQTVRWEQPKIHFTDRTYVSDAEAVIKELKDKRFKVGRDTLTTSQIRNLLSLTSTVYDEALSSGVENVMDQVAYLRVQFVYQSGRNEAVKKLVELSRILDILKIIQKHQKKQDLIRFCRYMEALVAYFKYHGGRD
>NZ_CP020017.1|WP_094243911.1|1873948_1876237_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MDKQSVDLFYGSLLHDIGKIVQRATQEKKRHTEIGAQFMKDYLSSKNILDQIKFHHYKELSNANIEDQSQAYIAYIADNIASGLDRREHNDEVKRKWNSQMNLEDIFSKFGSKPTKRFIQPRILDLDVNNIFPSENYQEFTSGEYAGILQKIKEAFTRIEFTGNYMQSTLNLLEATASFIPSSTNMQEAVDISLYDHLKMTAGFSQATFQYLTDQSRLNFKQELFENSRSFYKEKAFLLVSFDISGIQDFIYTITSKGAHKQLRSRSFYLDMISEWLIDDLLENCSLTRANLLYSGGGHTYLFLPNTKEMLNEIEKIESGFNQFFLKNFGTQLYVIFGHTAFCANEIMEGNSPKDYQAIFHRVSNQISQKKLHRYSADEIKSLNQGGKRSGRECAICHNTSQLVEDEGQDKCELCYRLEHFSRNIQEDDFFEINDQDTQYSLPIGPNAFLHQTSRKNIENHHFSGKVYAKNQLYTGLDQATHLWVADYSDLDRNEFSHYAQREWTQQGAGASIGIKRTAVLRCDVDDLGFGFMAGFSEQDGGRYNTFSRTATFSRNMSIFFKCYINQFAEENHLTIVYAGGDDVFIIGAWDDIIEFSVQLREYFIRWTNGKLTLSTGIGLFADKTPINIMARQTGELEDAAKDSGKDSIACFSDYFTFGYDTFIQEIYYGKLAIIRDFFAQENERGKSFIYKLLSLIRERDETDRITFARLAYYLARLEDTARNKENFRIFKQKMHDWFEDSEQIRQTELALLLYVYEIRKD
>NZ_CP020017.1|WP_094243912.1|1876229_1876976_-|CRISPR-associated-endoribonuclease-Cas6
MQQIKLNCSVEGKVENHLGTYFHGWLMQQLQPELVDELHSMKTNPFAIYVERRHDRLQFVVSLLNAEVIEIFSPILLSSKLTVITLEASRQKIFPIHNREISDLSEKDLADIFYRESARNTFDISFITPIAFKSGGDYVFFPDLRLFYQSLMRKYSYTFERDEKVDPEMLERLCESTQIVSYHIMSSYYKVHQSFIPGFKGTIRIRCRGNQTLMNFLDMLLKFGEYSGVGIKTGMGMGALQLKGESHG
>NZ_CP020017.1|WP_094243913.1|1877333_1877594_-|hypothetical-protein
MDEFYTEISIGTSVNFDEEIYATIPYEKENAYIFIIYRDMAKLVELGTNVIAAKFLYHYWEMKLAEYDSVSGEYKVTFFTSLNISE
>NZ_CP020017.1|WP_094243915.1|1878727_1879672_-|acetamidase/formamidase-family-protein
MAETHKCTTDTVHYTWHKEHEPILTIDSGDTVVFETREVSDNQFNFHSTTEAISELDWDFVYPLSGPVYINGAEPGDTLAVEILDLKTKHWGWTAVLPGLDLLAEDYPDAYLRTFDLSDGKYIHFSEDIKVPIEPFLGTMGVCPKDGDGTPIMPPGNFGGNLDVRQLTIGTTLYLPVQQAGALFSCGDGHAAQGDGEVCVSALECPMYASLKFTVIKASKKSIPSPQFQTKGGLTQKVNHDDFYGTTGVGPDLMTGAQEALRAMIDYVSETYNIEKIDAYLLASLCVDLKISEIVDAGQYVVSALLPLSIFNDS
>NZ_CP020017.1|WP_094243916.1|1879831_1880743_-|hypothetical-protein
MSGEEKITLNLRQQFESICRSWLQSVDMKQASVLNDPILQYLNLKWRLVNSVSRNVYYSKEFYCPVNLQDGLNQVKEKIEKGEDITPYLSKSIKNVEYNDMMLNDWGIHHLHLGTTTDKKDSFFVNRTGKILYVKFEKNKAYLIQIMEHNEWTNDNLIKIIHDNWPDLIAKYKLKGMDIDQKFTDKERQKLRNGGTTSPVKVGDISYFPLGLGYATNKQSNVVIEKKDQIVWNLNKLEKDITENFRTYYKEKIRESTDYKGDSFEFELEIRESDNETVITETKSNVSFCFGNYRNMLCGEQDG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MN693107	Marine virus AFVG_25M445, complete genome	1040-1074	3	0.914
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	NC_013518	Sebaldella termitidis ATCC 33386 plasmid pSTERM01, complete sequence	15295-15329	7	0.8
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MN694321	Marine virus AFVG_250M307, complete genome	17199-17233	8	0.771
NZ_CP020017_2	2.27\|1868792\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868792-1868826	35	NC_015902	Lactococcus lactis subsp. lactis bv. diacetylactis plasmid pVF50, complete sequence	23863-23897	8	0.771
NZ_CP020017_2	2.30\|1869007\|36\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1869007-1869042	36	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	40941-40976	8	0.778
NZ_CP020017_2	2.5\|1867211\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1867211-1867245	35	NZ_CP015354	Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence	94202-94236	9	0.743
NZ_CP020017_2	2.16\|1868005\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868005-1868039	35	MN694628	Marine virus AFVG_250M527, complete genome	25108-25142	9	0.743
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MH560358	Escherichia virus KFS-EC, complete genome	150795-150829	9	0.743
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MK327935	Escherichia phage vB_EcoM_G2494, complete genome	44133-44167	9	0.743
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MN850574	Escherichia phage kaaroe, complete genome	63945-63979	9	0.743
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MK448940	Streptococcus phage Javan444, complete genome	3199-3233	9	0.743
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MN693291	Marine virus AFVG_25M136, complete genome	58444-58478	9	0.743
NZ_CP020017_2	2.20\|1868291\|34\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868291-1868324	34	NZ_CP039853	Salinimonas sp. KX18D6 plasmid plas12, complete sequence	88402-88435	9	0.735
NZ_CP020017_2	2.28\|1868863\|37\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868863-1868899	37	NZ_CP028549	Klebsiella variicola strain WCHKP19 plasmid p1_020019, complete sequence	77746-77782	9	0.757
NZ_CP020017_2	2.28\|1868863\|37\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868863-1868899	37	NZ_CP026237	Citrobacter freundii complex sp. CFNIH3 plasmid pCFR-9161, complete sequence	210108-210144	9	0.757
NZ_CP020017_2	2.28\|1868863\|37\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868863-1868899	37	NZ_CP022155	Escherichia coli strain ABWA45 plasmid pABWA45_1, complete sequence	63879-63915	9	0.757
NZ_CP020017_2	2.35\|1869368\|34\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1869368-1869401	34	MK867354	Synechococcus phage S-SCSM1, complete genome	139340-139373	9	0.735
NZ_CP020017_2	2.12\|1867719\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1867719-1867753	35	MN657138	Carnobacterium sp. strain ANT_P1 plasmid pA1P4, complete sequence	3822-3856	10	0.714
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MN693520	Marine virus AFVG_25M327, complete genome	3264-3298	10	0.714
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MN693520	Marine virus AFVG_25M327, complete genome	59010-59044	10	0.714
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MF360958	Salicola phage SCTP-2, complete genome	168715-168749	10	0.714
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MK327932	Escherichia phage vB_EcoM_G2248, complete genome	128225-128259	10	0.714
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	KM236245	Bacillus phage Mater, complete genome	148703-148737	10	0.714
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MK448902	Streptococcus phage Javan308, complete genome	2617-2651	10	0.714
NZ_CP020017_2	2.27\|1868792\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868792-1868826	35	MT773556	Myoviridae sp. isolate BML_4 genomic sequence	36222-36256	10	0.714
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	MK448714	Streptococcus phage Javan241, complete genome	2670-2704	11	0.686
NZ_CP020017_2	2.19\|1868220\|35\|NZ_CP020017\|CRISPRCasFinder,CRT,PILER-CR	1868220-1868254	35	KF929199	Staphylococcus phage vB_SepS_SEP9, complete genome	64819-64853	11	0.686

1. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN693107 (Marine virus AFVG_25M445, complete genome) position: , mismatch: 3, identity: 0.914

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
agaaaaaagaaaaaaataaaaaaagttgttgacat	Protospacer
************* *****.**************

2. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NC_013518 (Sebaldella termitidis ATCC 33386 plasmid pSTERM01, complete sequence) position: , mismatch: 7, identity: 0.8

agaaaaaagaaaataataagaaaagttgttgacag-	CRISPR spacer
ggaaaaaagaaaatattaataaaag-tgtaaaaagt	Protospacer
.************** *** ***** *** .* **

3. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN694321 (Marine virus AFVG_250M307, complete genome) position: , mismatch: 8, identity: 0.771

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
agaaaaaagaaaatatgaagaaaagatatcgcaaa	Protospacer
***************  ******** *.*.*  *.

4. spacer 2.27|1868792|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NC_015902 (Lactococcus lactis subsp. lactis bv. diacetylactis plasmid pVF50, complete sequence) position: , mismatch: 8, identity: 0.771

atttaagcaaaaaaatactttacatcttagtaaat	CRISPR spacer
ggtaaaacaaaaacatactttacatcttagtagtc	Protospacer
. * **.****** ******************. .

5. spacer 2.30|1869007|36|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 8, identity: 0.778

--ggttttgacgatatttacgaagatatgatcgttggc	CRISPR spacer
ccaggtacg--gatatttacgaaggtatgatcgttggg	Protospacer
  .* * .*  *************.************

6. spacer 2.5|1867211|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015354 (Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence) position: , mismatch: 9, identity: 0.743

cgataaatgaaatcttaaatgcttcttctgctcta	CRISPR spacer
ccatcaatgaaattttaaatgcttcttcaattggt	Protospacer
* ** ********.************** ..*

7. spacer 2.16|1868005|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN694628 (Marine virus AFVG_250M527, complete genome) position: , mismatch: 9, identity: 0.743

aggaagtttagatgagaaaacacaaaagaaaattg	CRISPR spacer
agcagctttagatgagttaacacaaaagaaacaca	Protospacer
** *. **********  *************  ..

8. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MH560358 (Escherichia virus KFS-EC, complete genome) position: , mismatch: 9, identity: 0.743

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
taattcactaaaatcataaaaaaagttgttgacag	Protospacer
 .*   *  ***** ****.***************

9. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MK327935 (Escherichia phage vB_EcoM_G2494, complete genome) position: , mismatch: 9, identity: 0.743

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
taattcactaaaatcataaaaaaagttgttgacag	Protospacer
 .*   *  ***** ****.***************

10. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN850574 (Escherichia phage kaaroe, complete genome) position: , mismatch: 9, identity: 0.743

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
taattcactaaaatcataaaaaaagttgttgacag	Protospacer
 .*   *  ***** ****.***************

11. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MK448940 (Streptococcus phage Javan444, complete genome) position: , mismatch: 9, identity: 0.743

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
atattttataaaaaaataaaaaaagttgttgacaa	Protospacer
* *    * **** *****.**************.

12. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN693291 (Marine virus AFVG_25M136, complete genome) position: , mismatch: 9, identity: 0.743

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
atgtcaataaaaaaaataaaaaaagttgttgacat	Protospacer
* .  ** .**** *****.**************

13. spacer 2.20|1868291|34|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039853 (Salinimonas sp. KX18D6 plasmid plas12, complete sequence) position: , mismatch: 9, identity: 0.735

acagatcagggctaaagagctatgccctggtata	CRISPR spacer
ggacatcagggctaaagagtgatgccctgacgtc	Protospacer
. * ***************. ********...*

14. spacer 2.28|1868863|37|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028549 (Klebsiella variicola strain WCHKP19 plasmid p1_020019, complete sequence) position: , mismatch: 9, identity: 0.757

-gacaagtccatttactgccagtggctgcaaagcaaaa	CRISPR spacer
cggcta-tccattttctgccagtggttgcaaagacgac	Protospacer
 *.* * ******* **********.*******  .*

15. spacer 2.28|1868863|37|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026237 (Citrobacter freundii complex sp. CFNIH3 plasmid pCFR-9161, complete sequence) position: , mismatch: 9, identity: 0.757

-gacaagtccatttactgccagtggctgcaaagcaaaa	CRISPR spacer
cggcta-tccattttctgccagtggttgcaaagacgac	Protospacer
 *.* * ******* **********.*******  .*

16. spacer 2.28|1868863|37|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022155 (Escherichia coli strain ABWA45 plasmid pABWA45_1, complete sequence) position: , mismatch: 9, identity: 0.757

-gacaagtccatttactgccagtggctgcaaagcaaaa	CRISPR spacer
cggcta-tccattttctgccagtggttgcaaagacgac	Protospacer
 *.* * ******* **********.*******  .*

17. spacer 2.35|1869368|34|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MK867354 (Synechococcus phage S-SCSM1, complete genome) position: , mismatch: 9, identity: 0.735

tgacggcatgaacgaaaagcagaaagaaatatat	CRISPR spacer
ccatgacgggaacgaaaagcataaagaaatgtag	Protospacer
. *.*.*. ************ ********.**

18. spacer 2.12|1867719|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN657138 (Carnobacterium sp. strain ANT_P1 plasmid pA1P4, complete sequence) position: , mismatch: 10, identity: 0.714

actagtaaaagaaaattttcaagaaagatcaggaa	CRISPR spacer
cctagtaaaagaaaatctccaagaaagcactcctg	Protospacer
 ***************.*.********  *    .

19. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN693520 (Marine virus AFVG_25M327, complete genome) position: , mismatch: 10, identity: 0.714

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
ccaggcataaaaaaaataaaaaaagttgttgacat	Protospacer
  *.. * .**** *****.**************

20. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MN693520 (Marine virus AFVG_25M327, complete genome) position: , mismatch: 10, identity: 0.714

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
ccaggcataaaaaaaataaaaaaagttgttgacat	Protospacer
  *.. * .**** *****.**************

21. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MF360958 (Salicola phage SCTP-2, complete genome) position: , mismatch: 10, identity: 0.714

agaaaaaagaaaataat--------aagaaaagttgttgacag	CRISPR spacer
agaaaaaagaaaataatagaaaaagaaaaaaagtc--------	Protospacer
*****************        **.******.

22. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MK327932 (Escherichia phage vB_EcoM_G2248, complete genome) position: , mismatch: 10, identity: 0.714

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
atatgcgtataaagaataaaaaaagttgttgacag	Protospacer
* * . . . *** *****.***************

23. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to KM236245 (Bacillus phage Mater, complete genome) position: , mismatch: 10, identity: 0.714

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
agtcccctcaaaatattcagaaaagttgttgacaa	Protospacer
**       ****** * ****************.

24. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MK448902 (Streptococcus phage Javan308, complete genome) position: , mismatch: 10, identity: 0.714

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
atattttttaaaaaaataaaaaaagttgttgacaa	Protospacer
* *      **** *****.**************.

25. spacer 2.27|1868792|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MT773556 (Myoviridae sp. isolate BML_4 genomic sequence) position: , mismatch: 10, identity: 0.714

atttaagcaaaaaaatactttacatcttagtaaat	CRISPR spacer
aattaagcaaaaaaacgctttacatctgcttccga	Protospacer
* *************..**********   *  .

26. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to MK448714 (Streptococcus phage Javan241, complete genome) position: , mismatch: 11, identity: 0.686

--------agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
ctttttttaaaaaa--------aataaaaaaagttgttgacaa	Protospacer
        *.****        *****.**************.

27. spacer 2.19|1868220|35|NZ_CP020017|CRISPRCasFinder,CRT,PILER-CR matches to KF929199 (Staphylococcus phage vB_SepS_SEP9, complete genome) position: , mismatch: 11, identity: 0.686

agaaaaaagaaaataataagaaaagttgttgacag	CRISPR spacer
gaaaaaaagaaaatattaagaaaacttttgattca	Protospacer
..************* ******** ** * . . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

158204 : 166608

Bacillus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014123956.1\|158204_158978_+	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	1.2e-06	25.1
WP_094243242.1\|158992_160285_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_061840814.1\|160281_161517_+	cysteine desulfurase	Q2XUY6	environmental_halophage	6.9e-110	47.8
WP_061840813.1\|161503_161977_+	SUF system NifU family Fe-S cluster assembly protein	A0A2H4N7M4	Lake_Baikal_phage	4.5e-09	28.5
WP_061840812.1\|162083_162788_+	NAD-dependent protein deacylase	S5M4R0	Bacillus_phage	2.4e-22	30.9
WP_061840811.1\|163016_164756_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.6e-41	29.0
WP_069029204.1\|164745_166608_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.7e-38	26.1

DBSCAN-SWA_2

177047 : 185334

Lactobacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094244155.1\|177047_178286_-	NADPH-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.7e-63	62.9
WP_014123975.1\|178303_178912_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	3.7e-56	53.3
WP_014123976.1\|179111_179816_-	deoxynucleoside kinase	K4I4F1	Lactobacillus_phage	8.4e-44	40.2
WP_014123977.1\|180158_181628_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.2e-81	40.7
WP_014123978.1\|181855_183568_+	ABC transporter ATP-binding protein	F2Y1V6	Organic_Lake_phycodnavirus	1.8e-07	22.3
WP_103083365.1\|183567_185334_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.7e-49	27.1

DBSCAN-SWA_3

292465 : 300931

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061840414.1\|292465_293866_-	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	2.7e-41	28.9
WP_069029149.1\|294085_295828_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	1.7e-53	44.3
WP_061840413.1\|295845_296157_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_014124100.1\|296218_296815_+	recombination protein RecR	NA	NA	NA	NA
WP_094243282.1\|296844_297498_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-54	52.2
WP_014124102.1\|297494_297827_+	hypothetical protein	NA	NA	NA	NA
WP_061840411.1\|297869_298802_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.2e-35	35.0
WP_094243283.1\|298825_299656_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_094243284.1\|299642_299999_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.1e-07	62.2
WP_094243285.1\|300064_300931_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.0e-84	58.7

DBSCAN-SWA_4

388914 : 396042

Lactobacillus_phage(33.33%)

integrase

attL 388772:388798|attR 402316:402342

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
388772:388798	attL	NA	NA	NA	NA
WP_061840130.1\|388914_390060_-\|integrase	site-specific integrase	A0A172LN96	Lactococcus_phage	2.1e-68	40.5
WP_094243310.1\|390391_391384_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	2.3e-92	52.3
WP_157727964.1\|391462_392077_-	hypothetical protein	O64371	Lactobacillus_phage	1.7e-21	50.5
WP_094243312.1\|392343_392781_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_094243313.1\|392791_393214_-	helix-turn-helix transcriptional regulator	A0A2P1JU09	Anoxybacillus_phage	2.2e-23	42.9
WP_094243314.1\|393367_393940_+	helix-turn-helix transcriptional regulator	A0A139ZPI6	Marinitoga_camini_virus	8.1e-05	39.7
WP_157727966.1\|393951_394104_+	hypothetical protein	NA	NA	NA	NA
WP_094243315.1\|394521_394992_+	hypothetical protein	NA	NA	NA	NA
WP_094243316.1\|394992_395202_+	hypothetical protein	NA	NA	NA	NA
WP_094243317.1\|395241_396042_+	hypothetical protein	A0A2P0ZLG2	Lactobacillus_phage	4.0e-34	36.7
402316:402342	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1233149 : 1295354

Enterobacteria_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094243223.1\|1233149_1234568_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_094243613.1\|1234649_1236017_-\|transposase	transposase	NA	NA	NA	NA
WP_094243614.1\|1236278_1237571_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_014124622.1\|1237582_1238977_-	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_069028863.1\|1239112_1239895_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_061840435.1\|1240199_1240526_+	cupin domain-containing protein	NA	NA	NA	NA
WP_094243615.1\|1240526_1242158_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094243616.1\|1243047_1245015_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_094243617.1\|1245312_1246344_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_094243618.1\|1246356_1247325_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_094243619.1\|1247321_1248032_-	trehalose utilization protein ThuA	NA	NA	NA	NA
WP_094243620.1\|1248046_1249120_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_094243621.1\|1249283_1250159_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_094243622.1\|1250364_1251249_+	DUF368 domain-containing protein	NA	NA	NA	NA
WP_014123943.1\|1251813_1252674_+	group II intron reverse transcriptase/maturase	D4HTV9	Vibrio_phage	1.7e-14	29.8
WP_014123482.1\|1252727_1253084_+	reverse transcriptase	NA	NA	NA	NA
WP_013655060.1\|1253302_1254664_-\|transposase	transposase	NA	NA	NA	NA
WP_094243623.1\|1256381_1258016_-	alpha-glucosidase	NA	NA	NA	NA
WP_094243624.1\|1259780_1260779_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	3.3e-17	25.3
WP_103100298.1\|1260956_1263509_-	AAA family ATPase	NA	NA	NA	NA
WP_083207564.1\|1263621_1264332_-	HAD family hydrolase	NA	NA	NA	NA
WP_094243625.1\|1264333_1265161_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_014124595.1\|1265157_1265973_-	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_014124594.1\|1265991_1266489_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_061840446.1\|1266501_1266921_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_014124116.1\|1267304_1268627_+\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	7.4e-94	42.4
WP_094243626.1\|1268809_1269961_-	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_094243627.1\|1270221_1271823_+	hypothetical protein	NA	NA	NA	NA
WP_014124590.1\|1271837_1272959_+	hypothetical protein	NA	NA	NA	NA
WP_094243628.1\|1273141_1273372_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014124588.1\|1273379_1273562_-	hypothetical protein	NA	NA	NA	NA
WP_061840449.1\|1273689_1273929_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014124586.1\|1274103_1274430_-	putative beta-fructofuranosidase	NA	NA	NA	NA
WP_094243630.1\|1274679_1276002_-\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	5.7e-94	42.5
WP_014124585.1\|1276201_1277239_-	glycoside hydrolase family 32 protein	NA	NA	NA	NA
WP_014124582.1\|1279005_1279848_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_014124581.1\|1279895_1281557_-	alpha-glucosidase	NA	NA	NA	NA
WP_014124580.1\|1281750_1281990_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_081497498.1\|1282058_1282748_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	9.5e-08	24.9
WP_014124578.1\|1283063_1284113_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_094243631.1\|1284212_1285787_+	divalent metal cation transporter	NA	NA	NA	NA
WP_014124576.1\|1285779_1286211_+	universal stress protein	NA	NA	NA	NA
WP_014124575.1\|1286380_1287382_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094243632.1\|1287734_1289066_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_094243633.1\|1289198_1290494_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_094243634.1\|1290513_1290819_-	hypothetical protein	NA	NA	NA	NA
WP_094243635.1\|1291154_1291760_+	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_094243636.1\|1291759_1292455_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_094243637.1\|1292451_1293861_+	energy-coupling factor ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-16	30.0
WP_014125033.1\|1293992_1295354_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

1305441 : 1367329

Streptococcus_phage(26.67%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094243647.1\|1305441_1306770_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_094243648.1\|1307341_1308295_-	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_094243649.1\|1308312_1308771_-	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_094243650.1\|1308770_1310207_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_094243651.1\|1310213_1311140_-	1-phosphofructokinase	NA	NA	NA	NA
WP_094243652.1\|1311296_1312046_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_094243653.1\|1312269_1313631_-\|transposase	transposase	NA	NA	NA	NA
WP_094243654.1\|1314786_1315473_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_014124116.1\|1315739_1317062_-\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	7.4e-94	42.4
WP_094243655.1\|1317248_1318262_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_094243656.1\|1318558_1320550_-	transketolase	NA	NA	NA	NA
WP_094243657.1\|1320563_1321901_-	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_069028828.1\|1321918_1322188_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_083207560.1\|1322209_1322779_-	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	4.7e-13	30.6
WP_069028827.1\|1322796_1324743_-	BglG family transcription antiterminator	NA	NA	NA	NA
WP_094243658.1\|1324969_1325287_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_069028825.1\|1325287_1325539_-	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_094243659.1\|1325702_1326563_-	ROK family protein	NA	NA	NA	NA
WP_094243660.1\|1326578_1327952_-	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	1.4e-42	29.3
WP_069028822.1\|1327948_1329271_-	alpha-L-fucosidase	NA	NA	NA	NA
WP_094243661.1\|1329270_1330272_-	LacI family transcriptional regulator	NA	NA	NA	NA
WP_094244172.1\|1330300_1331620_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_094243662.1\|1331919_1332651_+	hypothetical protein	NA	NA	NA	NA
WP_094243663.1\|1332756_1333896_-	glycerate kinase	W6LM47	Streptococcus_phage	5.9e-47	38.3
WP_094243664.1\|1333924_1335190_-	GntP family permease	NA	NA	NA	NA
WP_094243665.1\|1335462_1335684_-	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_094243666.1\|1335673_1336729_-	YeeE/YedE family protein	NA	NA	NA	NA
WP_094243667.1\|1337172_1338483_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.6e-64	35.7
WP_061841221.1\|1338620_1339553_-	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_061841220.1\|1339623_1340541_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_061841219.1\|1340716_1341250_+	3'-5' exonuclease	B5WZL1	Staphylococcus_phage	1.6e-23	37.6
WP_094243668.1\|1341329_1341863_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_061841217.1\|1341864_1342329_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_061841216.1\|1342514_1343495_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_014124519.1\|1343646_1344327_-	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	1.9e-45	43.5
WP_061841214.1\|1344544_1345417_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_014124517.1\|1345471_1345999_+	hypothetical protein	NA	NA	NA	NA
WP_014124516.1\|1346036_1346603_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014124515.1\|1346681_1347137_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_014124514.1\|1347162_1347993_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_094243669.1\|1348175_1349978_-	sulfatase-like hydrolase/transferase	NA	NA	NA	NA
WP_014124512.1\|1350071_1350896_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	5.7e-76	55.7
WP_014124511.1\|1350920_1352387_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.4e-111	46.0
WP_094243670.1\|1352575_1353403_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_014124509.1\|1353946_1355587_-	chaperonin GroEL	A0A219YK78	uncultured_virus	6.3e-151	54.0
WP_014124508.1\|1355617_1355902_-	co-chaperone GroES	A0A221S465	uncultured_virus	9.5e-15	42.4
WP_069028806.1\|1356164_1356797_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_014124506.1\|1356845_1357652_-	MBL fold metallo-hydrolase	A0A2H4J3R0	uncultured_Caudovirales_phage	2.5e-36	37.7
WP_014124505.1\|1357704_1358568_-	hypothetical protein	NA	NA	NA	NA
WP_094243671.1\|1358572_1359892_-	hypothetical protein	NA	NA	NA	NA
WP_094243672.1\|1359888_1361724_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	2.2e-35	36.7
WP_094243673.1\|1361730_1362435_-	response regulator transcription factor	W8CYM9	Bacillus_phage	8.4e-44	42.0
WP_094243674.1\|1362854_1363889_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_014124499.1\|1364418_1365153_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	4.8e-66	50.8
WP_014124498.1\|1365318_1365516_-	hypothetical protein	NA	NA	NA	NA
WP_124175375.1\|1365534_1365660_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_094243676.1\|1365747_1366068_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_014123848.1\|1366222_1367329_+\|transposase	IS4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

1683164 : 1725843

Streptococcus_phage(28.57%)

transposase,tRNA,integrase

attL 1700051:1700076|attR 1722255:1722280

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094243738.1\|1683164_1684370_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	1.4e-78	43.6
WP_094243798.1\|1684664_1685639_-\|tRNA	tRNA-dihydrouridine synthase	NA	NA	NA	NA
WP_014123885.1\|1685829_1688361_+	DEAD/DEAH box helicase	Q9YNZ9	Choristoneura_fumiferana_nuclear_polyhedrosis_virus	1.1e-40	25.3
WP_061840043.1\|1688363_1689077_+	hypothetical protein	NA	NA	NA	NA
WP_038025595.1\|1689236_1689836_-	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_014123882.1\|1689849_1690833_-	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_014123881.1\|1690854_1691253_-	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
WP_014123880.1\|1691341_1692484_-	glycerol dehydrogenase	NA	NA	NA	NA
WP_014123879.1\|1692661_1693630_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_061840045.1\|1693762_1695376_-	gamma-glutamyltransferase	NA	NA	NA	NA
WP_146028686.1\|1695403_1696315_-	hypothetical protein	NA	NA	NA	NA
WP_094243800.1\|1696341_1696590_-	hypothetical protein	NA	NA	NA	NA
WP_094243801.1\|1697057_1697771_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_094243802.1\|1697904_1699836_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_094243803.1\|1699860_1701300_+	6-phospho-beta-glucosidase	NA	NA	NA	NA
1700051:1700076	attL	NA	NA	NA	NA
WP_014123873.1\|1701356_1701959_-	VanZ family protein	NA	NA	NA	NA
WP_094243804.1\|1704216_1704471_-	hypothetical protein	NA	NA	NA	NA
WP_028790175.1\|1706128_1706995_+	phytoene/squalene synthase family protein	NA	NA	NA	NA
WP_094243805.1\|1707011_1707551_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_094243806.1\|1707699_1708536_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_094243807.1\|1708680_1710132_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	5.9e-68	33.1
WP_094243808.1\|1710219_1711038_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_094244179.1\|1711302_1711662_+	hotdog fold thioesterase	NA	NA	NA	NA
WP_028790182.1\|1711928_1712183_-	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_094243809.1\|1712394_1713300_+	ribokinase	NA	NA	NA	NA
WP_094243810.1\|1713585_1714137_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_157728022.1\|1714254_1714359_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_094243811.1\|1714880_1715372_-	HAD hydrolase-like protein	NA	NA	NA	NA
WP_094243812.1\|1715505_1715775_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5S8E8	Streptococcus_phage	2.7e-19	51.2
WP_094243813.1\|1715771_1716005_-	toxin-antitoxin system, antitoxin component	NA	NA	NA	NA
WP_094243814.1\|1716183_1717410_-	MFS transporter	NA	NA	NA	NA
WP_157728051.1\|1717794_1717896_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_157728024.1\|1717993_1718194_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1P8CWQ3	Bacillus_phage	2.6e-11	52.6
WP_094243816.1\|1718224_1718476_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_094243817.1\|1718607_1718829_-\|transposase	transposase	NA	NA	NA	NA
WP_094243818.1\|1719009_1720974_-	transcription antiterminator	NA	NA	NA	NA
WP_094243819.1\|1721060_1722449_-	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	6.3e-43	26.5
1722255:1722280	attR	NA	NA	NA	NA
WP_094243820.1\|1722459_1722771_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_094243821.1\|1722808_1724077_-	PTS cellobiose transporter subunit IIC	NA	NA	NA	NA
WP_094243822.1\|1724592_1725843_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	8.3e-111	56.6

DBSCAN-SWA_8

1731537 : 1800674

Streptococcus_phage(40.0%)

transposase,integrase

attL 1771445:1771460|attR 1781177:1781192

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094243825.1\|1731537_1732860_-\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	6.7e-95	42.8
WP_094244180.1\|1733052_1734441_-	D-xylose transporter XylE	NA	NA	NA	NA
WP_094244181.1\|1734793_1736293_-	xylulokinase	NA	NA	NA	NA
WP_094243826.1\|1736311_1737619_-	xylose isomerase	NA	NA	NA	NA
WP_094243827.1\|1737987_1739148_+	ROK family protein	NA	NA	NA	NA
WP_094243828.1\|1739255_1740221_-	D-ribose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_094243829.1\|1740238_1741204_-	ribose ABC transporter permease	NA	NA	NA	NA
WP_094243830.1\|1741200_1742685_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.5e-14	29.5
WP_094243831.1\|1742696_1743095_-	D-ribose pyranase	NA	NA	NA	NA
WP_094243832.1\|1743069_1743978_-	ribokinase	NA	NA	NA	NA
WP_094243833.1\|1743982_1744957_-	LacI family transcriptional regulator	NA	NA	NA	NA
WP_094243834.1\|1745201_1746299_-	agmatine deiminase	M1HCB6	Acanthocystis_turfacea_Chlorella_virus	3.7e-99	49.4
WP_094243835.1\|1747742_1748762_-	putrescine carbamoyltransferase	A0A1J0F9B8	Only_Syngen_Nebraska_virus	1.9e-20	29.7
WP_094243836.1\|1751295_1752546_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	5.0e-100	53.9
WP_094243837.1\|1753396_1754440_-	galactose mutarotase	NA	NA	NA	NA
WP_094243838.1\|1754542_1755910_-	sugar porter family MFS transporter	O13311	Aichi_virus	3.8e-24	27.8
WP_094243839.1\|1755986_1757411_-	L-arabinose isomerase	NA	NA	NA	NA
WP_094243840.1\|1757453_1758152_-	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
WP_094243841.1\|1758173_1759769_-	FGGY-family carbohydrate kinase	NA	NA	NA	NA
WP_094243630.1\|1760386_1761709_+\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	5.7e-94	42.5
WP_094243842.1\|1762038_1763535_+	phytoene desaturase	NA	NA	NA	NA
WP_061840054.1\|1763515_1764382_+	phytoene/squalene synthase family protein	NA	NA	NA	NA
WP_069028693.1\|1764398_1764938_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_094243843.1\|1765491_1766700_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_061840057.1\|1766756_1768226_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_014123854.1\|1768468_1769029_+	hypothetical protein	NA	NA	NA	NA
WP_094244182.1\|1769078_1769942_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014123851.1\|1770341_1770575_-	hypothetical protein	NA	NA	NA	NA
WP_094243844.1\|1770642_1771194_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
1771445:1771460	attL	NA	NA	NA	NA
WP_014123850.1\|1771467_1771803_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SEX8	Streptococcus_phage	3.5e-16	43.5
WP_041591760.1\|1771795_1772032_-	hypothetical protein	NA	NA	NA	NA
WP_094243845.1\|1774269_1774749_+	UTRA domain-containing protein	NA	NA	NA	NA
WP_005225225.1\|1775919_1776612_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_005237709.1\|1776628_1777180_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	3.6e-18	36.8
WP_005237711.1\|1777520_1777700_-	hypothetical protein	NA	NA	NA	NA
WP_094243846.1\|1777864_1779184_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.2e-62	34.5
WP_068710626.1\|1779529_1780081_-\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	8.3e-31	41.7
WP_035020741.1\|1780320_1780938_-	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_094243847.1\|1781503_1781866_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
1781177:1781192	attR	NA	NA	NA	NA
WP_051923348.1\|1781871_1782147_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_094243848.1\|1782334_1784002_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_094243849.1\|1784071_1784182_-	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
WP_083498309.1\|1784218_1784392_-	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
WP_068710628.1\|1784369_1784711_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	7.7e-19	45.8
WP_094243850.1\|1784829_1786572_-	arsenical pump-driving ATPase	NA	NA	NA	NA
WP_094243851.1\|1786586_1786952_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_014123801.1\|1787207_1788638_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_094243852.1\|1788990_1790853_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.1e-98	35.1
WP_028791093.1\|1791067_1792357_-	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
WP_069028902.1\|1792937_1794227_-	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
WP_003103602.1\|1794792_1795026_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_094243853.1\|1796011_1796350_-	hypothetical protein	NA	NA	NA	NA
WP_014125710.1\|1796578_1797286_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_014125711.1\|1797470_1798043_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	2.8e-21	40.4
WP_094243854.1\|1799512_1800674_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.6e-79	51.3

DBSCAN-SWA_9

2294170 : 2302555

Staphylococcus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094244079.1\|2294170_2294671_-	dUTP diphosphatase	J9PV85	Bacillus_phage	1.1e-42	53.5
WP_094244194.1\|2294917_2295757_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.1e-57	45.9
WP_014123416.1\|2296007_2296814_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	5.4e-39	37.3
WP_014123415.1\|2296810_2298058_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	3.0e-113	54.8
WP_014123414.1\|2298238_2298436_+	hypothetical protein	NA	NA	NA	NA
WP_014123413.1\|2298597_2300220_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	4.9e-47	26.2
WP_014123412.1\|2300275_2301145_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	2.5e-13	30.9
WP_014123411.1\|2301262_2302555_-	adenylosuccinate synthase	L7Y4J5	Megavirus	5.2e-68	35.5

DBSCAN-SWA_10

2465188 : 2528331

Streptococcus_phage(42.86%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094244116.1\|2465188_2465869_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.1e-108	83.6
WP_014123534.1\|2466060_2466627_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_094244117.1\|2466675_2469333_+	MMPL family transporter	NA	NA	NA	NA
WP_094244116.1\|2469424_2470105_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.1e-108	83.6
WP_061841314.1\|2470231_2470933_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.6e-33	36.5
WP_061841311.1\|2475208_2475760_-	hypothetical protein	NA	NA	NA	NA
WP_061841310.1\|2475918_2476554_+	NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_061841309.1\|2476560_2477880_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	2.5e-89	43.0
WP_061841315.1\|2478228_2479194_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_094244118.1\|2479343_2480288_+	MoxR family ATPase	NA	NA	NA	NA
WP_094244119.1\|2480284_2481289_+	DUF58 domain-containing protein	NA	NA	NA	NA
WP_094244120.1\|2481293_2483453_+	transglutaminase domain-containing protein	NA	NA	NA	NA
WP_094244121.1\|2483677_2484730_+	CAP domain-containing protein	A0A0E3T7R5	Bacillus_phage	4.5e-17	38.4
WP_069029299.1\|2484877_2485426_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_094244122.1\|2485626_2487570_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_082786950.1\|2487874_2488432_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_014125755.1\|2488712_2489534_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_061841248.1\|2489841_2491266_+	DASS family sodium-coupled anion symporter	NA	NA	NA	NA
WP_014125752.1\|2491329_2492328_+	isocitrate/isopropylmalate dehydrogenase family protein	NA	NA	NA	NA
WP_014125751.1\|2492559_2493141_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_094244123.1\|2493245_2493563_+	hypothetical protein	NA	NA	NA	NA
WP_014125749.1\|2493905_2494601_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_094244124.1\|2494847_2495510_+	uracil-DNA glycosylase	NA	NA	NA	NA
WP_094244125.1\|2495853_2496345_+	CvpA family protein	NA	NA	NA	NA
WP_014125746.1\|2496498_2497260_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_094244126.1\|2497453_2497906_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_094244196.1\|2498008_2499046_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_094244127.1\|2499103_2499664_-	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	1.5e-16	31.1
WP_094244128.1\|2499750_2500068_+	hypothetical protein	NA	NA	NA	NA
WP_061841242.1\|2500131_2500899_+	DUF4111 domain-containing protein	NA	NA	NA	NA
WP_094244129.1\|2501209_2501740_-	type 1 glutamine amidotransferase	A0A0N7KVR4	Yellowstone_lake_phycodnavirus	4.0e-14	29.5
WP_094244130.1\|2501901_2503005_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	A0A218MNE0	uncultured_virus	3.3e-55	37.0
WP_094244131.1\|2503208_2503994_+	glutathione-dependent disulfide-bond oxidoreductase	NA	NA	NA	NA
WP_069029293.1\|2504206_2505706_+	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_094244132.1\|2505718_2506453_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-32	39.9
WP_061841237.1\|2506477_2507611_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_061841236.1\|2507720_2508545_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_094244133.1\|2508550_2509969_-	anion permease	NA	NA	NA	NA
WP_061841234.1\|2510159_2511413_+	AI-2E family transporter	NA	NA	NA	NA
WP_094244134.1\|2511502_2512330_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.0e-101	65.9
WP_094244135.1\|2512759_2513791_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_094244136.1\|2513945_2515052_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_041591859.1\|2515409_2515688_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014125725.1\|2515677_2516310_+	DUF1648 domain-containing protein	NA	NA	NA	NA
WP_041591858.1\|2516450_2516666_-	hypothetical protein	NA	NA	NA	NA
WP_014125696.1\|2516969_2517656_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	7.7e-127	99.1
WP_050989788.1\|2517749_2517968_+	hypothetical protein	NA	NA	NA	NA
WP_014124169.1\|2518527_2519826_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	6.5e-34	29.0
WP_014125704.1\|2521263_2521641_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_050989786.1\|2522084_2522786_-	hypothetical protein	NA	NA	NA	NA
WP_094244137.1\|2522919_2523600_+\|transposase	IS6-like element ISTeha2 family transposase	A0A1X9I6C6	Streptococcus_phage	2.6e-111	83.2
WP_014125700.1\|2523834_2525529_-	oleate hydratase	NA	NA	NA	NA
WP_014125699.1\|2525568_2525703_-	hypothetical protein	NA	NA	NA	NA
WP_094244138.1\|2526636_2527479_+	hypothetical protein	NA	NA	NA	NA
WP_002354485.1\|2527644_2528331_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020017

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection