CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP022697	Citrobacter farmeri strain AUSMDU00008141 plasmid pAUSMDU8141-2, complete sequence	0 crisprs	NA	0	2
NZ_CP022698	Citrobacter farmeri strain AUSMDU00008141 plasmid pAUSMDU8141-3, complete sequence	0 crisprs	NA	0	2
NZ_CP022696	Citrobacter farmeri strain AUSMDU00008141 plasmid pAUSMDU8141-1, complete sequence	0 crisprs	csa3	0	3
NZ_CP022695	Citrobacter farmeri strain AUSMDU00008141 chromosome, complete genome	2 crisprs	PD-DExK,DEDDh,WYL,DinG,cas3,csa3	1	8

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1365 : 75874

Escherichia_phage(33.33%)

protease,transposase,integrase

attL 1182:1195|attR 33389:33402

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1182:1195	attL	NA	NA	NA	NA
WP_022652310.1\|1365_2106_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
WP_001572362.1\|3181_4204_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_022652309.1\|4710_6189_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	1.9e-194	73.2
WP_032430841.1\|6206_7034_+	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	4.9e-51	40.3
WP_022652307.1\|7115_7319_+	hypothetical protein	NA	NA	NA	NA
WP_021314637.1\|7596_7827_-	thioredoxin family protein	NA	NA	NA	NA
WP_050483874.1\|8998_9508_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_022652300.1\|10098_11052_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_022652302.1\|11672_12383_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-31	37.7
WP_022652303.1\|12384_13590_-	ABC transporter permease	NA	NA	NA	NA
WP_022652304.1\|13586_14738_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004393990.1\|14734_15343_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_022652300.1\|15530_16484_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_000493286.1\|16902_17232_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	2.4e-09	44.2
WP_000780222.1\|17212_17494_+	helix-turn-helix transcriptional regulator	A0A2I6TC97	Escherichia_phage	1.3e-08	38.0
WP_016947617.1\|17771_18752_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	98.8
WP_022652299.1\|19074_19683_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_022652298.1\|20059_21871_+	beta-glucuronidase	B9U1V4	Vaccinia_virus	1.1e-302	79.8
WP_022652297.1\|21867_23241_+	glucuronide transporter	NA	NA	NA	NA
WP_022652296.1\|23289_24555_+	glucuronide uptake porin UidC	NA	NA	NA	NA
WP_022652295.1\|24856_26041_+	mannonate dehydratase	NA	NA	NA	NA
WP_022652294.1\|26147_27617_+	fructuronate reductase	H8ZJP8	Ostreococcus_tauri_virus	6.9e-48	29.8
WP_022652293.1\|27636_29067_+	glucuronate isomerase	NA	NA	NA	NA
WP_032430963.1\|29284_30073_+	Uxu operon transcriptional regulator	NA	NA	NA	NA
WP_022652290.1\|30955_33853_-\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	1.2e-181	37.7
33389:33402	attR	NA	NA	NA	NA
WP_001067855.1\|34157_34862_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001138070.1\|35082_38049_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
WP_000427619.1\|38127_39132_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_000954592.1\|39313_39490_-	DUF4102 domain-containing protein	T1S9J3	Salmonella_phage	1.0e-06	68.6
WP_001043260.1\|39819_40635_+	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
WP_000251875.1\|40721_41024_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001445143.1\|40917_41169_-	hypothetical protein	NA	NA	NA	NA
WP_001120888.1\|41199_42693_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000743213.1\|42903_43128_-	hypothetical protein	NA	NA	NA	NA
WP_001446887.1\|43124_43862_-	recombinase family protein	NA	NA	NA	NA
WP_001044210.1\|44347_44488_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|44493_45198_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001239317.1\|45277_45778_+	hypothetical protein	NA	NA	NA	NA
WP_001011939.1\|45927_46569_+	type A-2 chloramphenicol O-acetyltransferase CatII	G3CFL0	Escherichia_phage	7.3e-55	45.9
WP_001067855.1\|46712_47417_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000113282.1\|47428_48085_-	tetracycline resistance transcriptional repressor TetR(D)	NA	NA	NA	NA
WP_001039466.1\|48180_49365_+	tetracycline efflux MFS transporter Tet(D)	NA	NA	NA	NA
WP_000842134.1\|49459_50569_+	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.8e-33	30.2
WP_001067855.1\|51058_51763_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_022652277.1\|52423_54583_-	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	5.4e-25	25.5
WP_001567323.1\|54582_55836_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_001567322.1\|55838_56489_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000027057.1\|57549_58410_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|58592_59150_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_001143760.1\|59313_62319_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
WP_022652279.1\|63370_64027_-	recombinase family protein	NA	NA	NA	NA
WP_022652281.1\|66325_67306_-\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	3.0e-185	99.1
WP_022652283.1\|67700_68312_+	DUF2913 family protein	NA	NA	NA	NA
WP_022652284.1\|68308_69259_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	2.0e-77	55.9
WP_040219232.1\|69405_69606_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|69739_70444_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000612591.1\|71783_72131_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|72127_72508_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_052687741.1\|72635_73841_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.0e-09	36.2
WP_045342033.1\|73940_74258_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|75169_75874_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

DBSCAN-SWA_2

137539 : 147467

Stx2-converting_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022652318.1\|137539_138505_-	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	8.8e-137	77.5
WP_022652317.1\|138504_139671_-	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	1.1e-218	94.3
WP_032430835.1\|140496_141855_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	1.3e-117	47.5
WP_094465919.1\|141911_143435_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.5e-257	87.1
WP_000609174.1\|143484_143832_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.7e-59	95.7
WP_001201739.1\|143828_144212_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.1e-13	36.3
WP_022652315.1\|144320_145472_-\|transposase	IS30-like element IS30 family transposase	W5R8L2	Staphylococcus_phage	9.8e-42	35.3
WP_077873527.1\|146573_147467_-\|transposase	IS5 family transposase	Q38213	Escherichia_phage	4.3e-154	86.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP022698

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

50 : 9300

Escherichia_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004118283.1\|50_917_+	replication initiation protein	A0A222YYK1	Escherichia_phage	1.5e-23	31.1
WP_011977818.1\|2026_3232_+	ParA family protein	A0A077SL49	Escherichia_phage	5.3e-163	69.3
WP_011977819.1\|3231_4206_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	1.4e-86	53.8
WP_011977820.1\|4287_5559_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	1.1e-150	63.3
WP_001568036.1\|5558_5990_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.1e-29	53.3
WP_011977821.1\|6223_7195_+	mediator of plasmid stability	A0A222YXF2	Escherichia_phage	8.2e-74	46.8
WP_032435767.1\|7197_7869_+	Mediator of plasmid stability	NA	NA	NA	NA
WP_001568040.1\|7931_8162_+	hypothetical protein	NA	NA	NA	NA
WP_011977792.1\|8598_9300_+	DNA methylase	A0A2I7RE86	Vibrio_phage	2.4e-27	36.7

DBSCAN-SWA_2

53703 : 84699

Escherichia_phage(25.0%)

integrase,transposase

attL 61305:61319|attR 95966:95980

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085956494.1\|53703_54907_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	4.8e-100	62.2
WP_004198206.1\|54941_55631_+	hypothetical protein	NA	NA	NA	NA
WP_004153015.1\|58071_63333_+	conjugative transfer relaxase/helicase TraI	NA	NA	NA	NA
61305:61319	attL	NA	NA	NA	NA
WP_004152379.1\|63413_64139_+	type-F conjugative transfer system pilin acetylase TraX	A0A1D6ZIU7	Xanthomonas_phage	7.1e-06	28.8
WP_004152380.1\|64210_64804_+	fertility inhibition protein FinO	NA	NA	NA	NA
WP_015060010.1\|64964_65567_+	hypothetical protein	NA	NA	NA	NA
WP_004153014.1\|65616_66261_+	hypothetical protein	NA	NA	NA	NA
WP_004152382.1\|66316_66967_+	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_004152383.1\|66963_67272_+	hypothetical protein	K7PKY8	Enterobacterial_phage	1.1e-08	31.7
WP_014343478.1\|67447_67927_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	2.7e-17	31.7
WP_013609506.1\|68044_68314_+	replication regulatory protein RepA	NA	NA	NA	NA
WP_004171450.1\|68545_68623_+	RepA leader peptide Tap	NA	NA	NA	NA
WP_004152386.1\|68615_69473_+	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_072093200.1\|69523_69682_+	hypothetical protein	NA	NA	NA	NA
WP_072093201.1\|69766_69901_-	hypothetical protein	NA	NA	NA	NA
WP_004152388.1\|70691_71255_+	hypothetical protein	NA	NA	NA	NA
WP_004152389.1\|71238_71850_+	DUF2913 family protein	NA	NA	NA	NA
WP_004152390.1\|72058_72220_-	hypothetical protein	NA	NA	NA	NA
WP_001145103.1\|72246_73239_-	hypothetical protein	NA	NA	NA	NA
WP_001404092.1\|73287_73443_-	hypothetical protein	NA	NA	NA	NA
WP_004152391.1\|73737_75453_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_004152392.1\|75562_78592_+\|transposase	IS3-like element Tn4401 family transposase	NA	NA	NA	NA
WP_004199214.1\|78698_79724_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
WP_004152394.1\|79720_80500_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
WP_004199234.1\|80787_81669_+	carbapenem-hydrolyzing class A beta-lactamase KPC-2	A0A1B0VBP7	Salmonella_phage	2.2e-73	52.2
WP_004152397.1\|81918_83238_-\|transposase	IS1182-like element ISKpn6 family transposase	Q9MBP7	Staphylococcus_prophage	1.9e-12	24.2
WP_004152398.1\|83514_84699_-\|transposase	ISAs1-like element ISKpn31 family transposase	NA	NA	NA	NA
95966:95980	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP022696

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

22628 : 110478

Escherichia_phage(30.0%)

protease,transposase,integrase

attL 63899:63958|attR 93782:94603

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072201439.1\|22628_23597_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	3.9e-185	99.1
WP_000952689.1\|24040_24493_+	hypothetical protein	NA	NA	NA	NA
WP_000836981.1\|24482_24908_+	hypothetical protein	NA	NA	NA	NA
WP_000235773.1\|24916_25471_+	plasmid transfer protein	NA	NA	NA	NA
WP_001232109.1\|25590_29895_+	hypothetical protein	NA	NA	NA	NA
WP_001286760.1\|30172_30685_+	signal peptidase I	NA	NA	NA	NA
WP_001256132.1\|30671_32183_+	hypothetical protein	NA	NA	NA	NA
WP_001447965.1\|32321_33383_+	TraU family protein	NA	NA	NA	NA
WP_000776701.1\|33401_36590_+	conjugal transfer protein TraN	NA	NA	NA	NA
WP_000771834.1\|36618_37491_-	hypothetical protein	NA	NA	NA	NA
WP_000517885.1\|37670_39455_+	ATP-dependent helicase	G3MA40	Bacillus_virus	6.0e-22	23.1
WP_000041927.1\|39849_40722_+	hypothetical protein	NA	NA	NA	NA
WP_000120822.1\|40779_41157_+	hypothetical protein	NA	NA	NA	NA
WP_000810361.1\|41217_42195_+	hypothetical protein	NA	NA	NA	NA
WP_000063335.1\|42252_43311_+	AAA family ATPase	NA	NA	NA	NA
WP_001176645.1\|43442_43616_+	hypothetical protein	NA	NA	NA	NA
WP_000174396.1\|43679_44807_+	DUF3150 domain-containing protein	NA	NA	NA	NA
WP_000762700.1\|44883_46890_+	VWA domain-containing protein	NA	NA	NA	NA
WP_000192120.1\|46962_47184_+	hypothetical protein	NA	NA	NA	NA
WP_000220379.1\|47297_48530_+	hypothetical protein	NA	NA	NA	NA
WP_001011130.1\|48799_49321_+	hypothetical protein	NA	NA	NA	NA
WP_000762003.1\|49399_50278_+	hypothetical protein	NA	NA	NA	NA
WP_000691119.1\|50347_51283_+	hypothetical protein	NA	NA	NA	NA
WP_000991697.1\|51351_52272_+	hypothetical protein	NA	NA	NA	NA
WP_000472041.1\|52338_53277_+	hypothetical protein	NA	NA	NA	NA
WP_000149830.1\|53448_54405_+	hypothetical protein	NA	NA	NA	NA
WP_001004200.1\|54668_54944_+	hypothetical protein	NA	NA	NA	NA
WP_000578891.1\|54988_55579_+	hypothetical protein	NA	NA	NA	NA
WP_001371933.1\|55586_55844_+	hypothetical protein	NA	NA	NA	NA
WP_000107167.1\|55917_56454_+	hypothetical protein	NA	NA	NA	NA
WP_001424628.1\|56533_56917_+	hypothetical protein	NA	NA	NA	NA
WP_000119428.1\|57007_57970_+	hypothetical protein	NA	NA	NA	NA
WP_001198595.1\|57979_58885_+	hypothetical protein	NA	NA	NA	NA
WP_000795949.1\|59186_60362_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001285422.1\|60531_60744_+	hypothetical protein	NA	NA	NA	NA
WP_033487958.1\|61104_62187_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|62766_63471_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
63899:63958	attL	NA	NA	NA	NA
WP_032488579.1\|64074_64629_+	aminoglycoside N-acetyltransferase AAC(6')-Ib3	NA	NA	NA	NA
63899:63958	attL	NA	NA	NA	NA
WP_012695455.1\|64856_65597_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	4.4e-43	41.7
WP_077249983.1\|65583_67092_-\|transposase	IS21-like element ISCfr8 family transposase	A0A2L1IVA1	Escherichia_phage	9.9e-26	32.7
WP_001067855.1\|67251_67956_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_011191340.1\|68214_68463_+	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_001173919.1\|68589_69165_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	5.6e-46	52.7
WP_000845048.1\|69507_70521_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001261740.1\|70666_71458_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
70522:70635	attR	NA	NA	NA	NA
WP_000679427.1\|71621_71969_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
70522:70635	attR	NA	NA	NA	NA
WP_000259031.1\|71962_72802_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000376623.1\|72929_73430_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001389365.1\|73936_74701_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_000050481.1\|75163_76705_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_012579084.1\|76968_77625_+	quinolone resistance pentapeptide repeat protein QnrA1	NA	NA	NA	NA
WP_004193231.1\|77810_78686_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025999322.1\|78689_79055_-	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_052238321.1\|78947_79283_+	ethidium bromide resistance protein	NA	NA	NA	NA
WP_000259031.1\|79276_80116_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000050481.1\|80520_82062_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_012579084.1\|82325_82982_+	quinolone resistance pentapeptide repeat protein QnrA1	NA	NA	NA	NA
WP_004193231.1\|83167_84043_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025999322.1\|84046_84412_-	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_052238321.1\|84304_84640_+	ethidium bromide resistance protein	NA	NA	NA	NA
WP_000259031.1\|84633_85473_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000050481.1\|85877_87419_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_002008781.1\|87684_88185_+	hypothetical protein	A0A1V0SB21	Catovirus	3.3e-10	31.7
WP_000019304.1\|88184_88754_+	trimethoprim-resistant dihydrofolate reductase DfrA19	A0A1V0SD48	Indivirus	3.5e-08	27.2
WP_000845039.1\|89356_90370_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001082319.1\|90527_91331_+	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_000480968.1\|91330_92167_+	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_004248792.1\|92347_93139_+\|protease	zinc metalloprotease	NA	NA	NA	NA
WP_000057569.1\|93153_93495_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|93834_94539_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000113282.1\|94550_95207_-	tetracycline resistance transcriptional repressor TetR(D)	NA	NA	NA	NA
WP_001039466.1\|95302_96487_+	tetracycline efflux MFS transporter Tet(D)	NA	NA	NA	NA
WP_000842134.1\|96581_97691_+	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.8e-33	30.2
WP_001067855.1\|98180_98885_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000252081.1\|99194_100088_+	hypothetical protein	NA	NA	NA	NA
WP_001371935.1\|100259_100490_+	hypothetical protein	NA	NA	NA	NA
WP_000071366.1\|100668_100989_+	hypothetical protein	NA	NA	NA	NA
WP_001165367.1\|101505_101817_+	DUF957 domain-containing protein	NA	NA	NA	NA
WP_001371932.1\|101821_102313_+	DUF3085 domain-containing protein	NA	NA	NA	NA
WP_000781547.1\|102865_103069_+	hypothetical protein	NA	NA	NA	NA
WP_000551490.1\|103123_103348_+	hypothetical protein	NA	NA	NA	NA
WP_000814953.1\|103387_103588_+	hypothetical protein	NA	NA	NA	NA
WP_000633161.1\|103810_104122_+	hypothetical protein	NA	NA	NA	NA
WP_000802040.1\|104175_104352_+	hypothetical protein	NA	NA	NA	NA
WP_000703842.1\|104497_104779_+	hypothetical protein	NA	NA	NA	NA
WP_000137794.1\|104995_105601_+	hypothetical protein	NA	NA	NA	NA
WP_085949440.1\|105933_107302_+\|transposase	IS3-like element ISKpn8 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	9.4e-108	95.5
WP_000589001.1\|107477_108818_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_000219087.1\|109239_110478_+\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	2.5e-11	23.1

DBSCAN-SWA_2

153633 : 185734

uncultured_Caudovirales_phage(42.86%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100185530.1\|153633_154548_+\|transposase	IS5 family transposase	A0A077SK28	Escherichia_phage	3.6e-172	98.4
WP_000900745.1\|154713_155031_+	hypothetical protein	NA	NA	NA	NA
WP_001371904.1\|155081_155489_-	hypothetical protein	NA	NA	NA	NA
WP_000285959.1\|155946_156618_-	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_001100610.1\|156662_156968_-	hypothetical protein	NA	NA	NA	NA
WP_000785965.1\|156990_157308_-	hypothetical protein	NA	NA	NA	NA
WP_001567368.1\|157521_158925_+\|transposase	ISNCY-like element ISKpn21 family transposase	NA	NA	NA	NA
WP_001567369.1\|158953_159586_-	hypothetical protein	NA	NA	NA	NA
WP_022652343.1\|159660_160629_+\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	3.7e-183	98.1
WP_000125668.1\|160848_162252_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_000130816.1\|162284_162989_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	8.8e-86	72.9
WP_000941305.1\|163075_163396_+	transcriptional regulator	A0A2H4J145	uncultured_Caudovirales_phage	1.7e-20	53.7
WP_000922628.1\|163441_164731_+	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	9.9e-168	71.4
WP_000065802.1\|164743_165169_+	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	1.6e-50	70.7
WP_001066652.1\|165228_166056_-	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	4.9e-43	37.2
WP_000927306.1\|166074_167553_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	7.3e-199	74.4
WP_000864986.1\|168044_168320_-	hypothetical protein	NA	NA	NA	NA
WP_001371914.1\|168460_168658_-	hypothetical protein	NA	NA	NA	NA
WP_000637193.1\|169644_169902_-	hypothetical protein	NA	NA	NA	NA
WP_001005009.1\|169975_170290_-	hypothetical protein	NA	NA	NA	NA
WP_000975181.1\|170337_171234_-	hypothetical protein	NA	NA	NA	NA
WP_000464825.1\|171236_171752_-	thermonuclease family protein	A0A1X6WF84	Pacmanvirus	2.1e-07	38.6
WP_000833380.1\|171966_173394_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	3.4e-100	52.3
WP_000220758.1\|173454_173622_+	hypothetical protein	A0A2D2W2Z9	Escherichia_phage	7.3e-07	50.9
WP_000078513.1\|173644_174964_+	DUF1173 family protein	NA	NA	NA	NA
WP_000121164.1\|174976_175180_+	hypothetical protein	NA	NA	NA	NA
WP_001371952.1\|175243_176449_-	hypothetical protein	NA	NA	NA	NA
WP_000193207.1\|176445_177264_-	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_000019951.1\|177729_178002_-	Ni(II)/Co(II)-binding transcriptional repressor RcnR	NA	NA	NA	NA
WP_001572377.1\|178124_179240_+	nickel/cobalt efflux protein RcnA	NA	NA	NA	NA
WP_000723070.1\|179497_179932_-	hypothetical protein	NA	NA	NA	NA
WP_004248839.1\|180149_181496_-	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	8.8e-18	26.6
WP_072196614.1\|181534_182503_+\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	1.1e-184	98.8
WP_001572373.1\|182691_184311_+	phosphoethanolamine--lipid A transferase MCR-9.1	NA	NA	NA	NA
WP_001572372.1\|184387_184864_+	WbuC family cupin fold metalloprotein	NA	NA	NA	NA
WP_001067855.1\|185029_185734_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

DBSCAN-SWA_3

217713 : 293027

Escherichia_phage(52.0%)

protease,transposase,integrase

attL 210426:210438|attR 220985:220997

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
210426:210438	attL	NA	NA	NA	NA
WP_000174662.1\|217713_218478_+\|integrase	tyrosine-type recombinase/integrase	I3WFA4	Macacine_betaherpesvirus	1.9e-25	52.4
WP_001067855.1\|218954_219659_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001143760.1\|223450_226456_-\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
220985:220997	attR	NA	NA	NA	NA
WP_001235713.1\|226619_227177_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000027057.1\|227359_228220_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001371925.1\|228549_228930_+	hypothetical protein	NA	NA	NA	NA
WP_000490638.1\|228987_229653_+	hypothetical protein	NA	NA	NA	NA
WP_000175475.1\|230207_230444_+	hypothetical protein	NA	NA	NA	NA
WP_001100635.1\|230469_230763_+	hypothetical protein	NA	NA	NA	NA
WP_001287391.1\|230940_231345_+	H-NS histone family protein	NA	NA	NA	NA
WP_000784387.1\|231951_232809_-	HNH endonuclease	G0X580	Salmonella_phage	3.9e-11	34.2
WP_001224686.1\|232824_233133_-	hypothetical protein	NA	NA	NA	NA
WP_000278471.1\|233681_234107_-	hypothetical protein	NA	NA	NA	NA
WP_001166628.1\|234784_235240_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_001294656.1\|235311_235677_+	mercuric ion transporter MerT	NA	NA	NA	NA
WP_000732275.1\|235692_235968_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_000522996.1\|235995_236421_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000209296.1\|236459_238145_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_001277466.1\|238162_238528_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_001087807.1\|238524_238761_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001446012.1\|238744_238864_-	hypothetical protein	NA	NA	NA	NA
WP_000993245.1\|238826_239039_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_094465914.1\|239047_240124_-	lipoprotein signal peptidase	NA	NA	NA	NA
WP_033488201.1\|240120_242526_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.9e-141	46.0
WP_000405672.1\|242611_243046_+	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_050868990.1\|243136_244141_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_001805097.1\|244322_244847_-	hypothetical protein	NA	NA	NA	NA
WP_000985909.1\|244859_245270_-	hypothetical protein	NA	NA	NA	NA
WP_000134171.1\|245370_245577_-	hypothetical protein	NA	NA	NA	NA
WP_000088044.1\|245637_246963_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_012477377.1\|246967_247261_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012695445.1\|247661_249050_-	hypothetical protein	NA	NA	NA	NA
WP_000340139.1\|249054_249552_-	membrane protein	NA	NA	NA	NA
WP_000462754.1\|249754_250411_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_000341066.1\|251069_251462_-	hypothetical protein	NA	NA	NA	NA
WP_000211823.1\|252382_253369_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|254289_254994_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001389365.1\|255064_255829_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001137892.1\|256321_256906_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000004159.1\|256905_258144_-	MFS transporter	NA	NA	NA	NA
WP_000219391.1\|258140_259046_-	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
WP_001067855.1\|259167_259872_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000557454.1\|260104_260965_+	aminoglycoside N-acetyltransferase AAC(3)-IId	NA	NA	NA	NA
WP_000587837.1\|260977_261520_+	AAA family ATPase	NA	NA	NA	NA
WP_000951934.1\|262001_262193_-	hypothetical protein	NA	NA	NA	NA
WP_000248278.1\|262216_262444_+	hypothetical protein	NA	NA	NA	NA
WP_000080861.1\|262494_263631_+	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_014342212.1\|263597_263747_-	hypothetical protein	NA	NA	NA	NA
WP_000971921.1\|263745_265116_+\|transposase	IS1182-like element ISCfr1 family transposase	NA	NA	NA	NA
WP_014342213.1\|265257_265383_-	hypothetical protein	NA	NA	NA	NA
WP_000027057.1\|265936_266797_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_000427619.1\|267322_268327_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_001138070.1\|268405_271372_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.9
WP_001067855.1\|271492_272197_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000130000.1\|272476_272782_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000184001.1\|272792_273998_-	chromate efflux transporter	NA	NA	NA	NA
WP_000376616.1\|274153_274357_-	hypothetical protein	NA	NA	NA	NA
WP_000259031.1\|274484_275324_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|275317_275665_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001749986.1\|275887_276340_-	NAD(+)--rifampin ADP-ribosyltransferase Arr-3	NA	NA	NA	NA
WP_000186237.1\|276424_277057_-	type B-3 chloramphenicol O-acetyltransferase CatB3	A0A2R8FE91	Brazilian_cedratvirus	4.1e-26	41.2
WP_001334766.1\|277194_278025_-	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_063840321.1\|278155_278710_-	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
WP_001067855.1\|280272_280977_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_002904004.1\|281113_281974_+	class A extended-spectrum beta-lactamase SHV-12	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002210513.1\|281994_282756_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002903955.1\|283017_283920_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_011977770.1\|285176_285608_+	hypothetical protein	A0A077SK32	Escherichia_phage	2.9e-55	97.3
WP_001067855.1\|285553_286258_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001239317.1\|286337_286838_+	hypothetical protein	NA	NA	NA	NA
WP_001011939.1\|286987_287629_+	type A-2 chloramphenicol O-acetyltransferase CatII	G3CFL0	Escherichia_phage	7.3e-55	45.9
WP_001067855.1\|287772_288477_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000159617.1\|288992_289187_-	hypothetical protein	NA	NA	NA	NA
WP_000172888.1\|289183_289495_-	hypothetical protein	NA	NA	NA	NA
WP_001180999.1\|289557_289797_-	hypothetical protein	NA	NA	NA	NA
WP_000140246.1\|291612_291942_-	hypothetical protein	NA	NA	NA	NA
WP_072223036.1\|292058_293027_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.8e-185	99.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP022695

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022695_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022695_1

633190-633265

Orphan

Consensus_repeat	Method
GATAAGAGAAGCGCCATCAGGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022695_1

>merge|NZ_CP022695|1|633190-633265|CRISPRCasFinder
GATAAGAGAAGCGCCATCAGGCGAAGTAGGAGGAGGTCGAGTGCGTAGGCCTGATAAGCGAAGCGCCATCAGGCGA

>NZ_CP022695|1|1|633190-633265|CRISPRCasFinder
GATAAGAGAAGCGCCATCAGGCGA	AGTAGGAGGAGGTCGAGTGCGTAGGCCT
GATAAGCGAAGCGCCATCAGGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022695.1\|WP_042325246.1\|636191_636968_-\|transcriptional-regulator-ExuR	unknown	unknown	gnl\|CDD\|183176
NZ_CP022695.1\|WP_042325251.1\|640304_641792_+\|altronate-dehydratase	unknown	unknown	gnl\|CDD\|377287
NZ_CP022695.1\|WP_042325253.1\|641949_642504_+\|YgjV-family-protein	unknown	unknown	gnl\|CDD\|378474
NZ_CP022695.1\|WP_042325225.1\|629072_629234_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022695.1\|WP_042325243.1\|634803_635187_-\|EnvZ/OmpR-regulon-moderator-MzrA	unknown	unknown	gnl\|CDD\|236728
NZ_CP022695.1\|WP_042325224.1\|627657_628971_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP022695.1\|WP_042325241.1\|634286_634655_-\|DUF1090-domain-containing-protein	unknown	unknown	gnl\|CDD\|368932
NZ_CP022695.1\|WP_042325231.1\|631012_631384_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP022695.1\|WP_042325334.1\|633540_633945_-\|membrane-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP022695.1\|WP_042325248.1\|638877_640290_+\|glucuronate-isomerase	unknown	unknown	gnl\|CDD\|376859
NZ_CP022695.1\|WP_042325222.1\|626304_627636_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP022695.1\|WP_042325226.1\|629252_629954_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP022695.1\|WP_042325244.1\|635190_635853_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP022695.1\|WP_042325238.1\|633947_634253_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP022695.1\|WP_042325335.1\|637105_638407_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273326
NZ_CP022695.1\|WP_042325218.1\|622189_624484_+\|formate-C-acetyltransferase	unknown	unknown	gnl\|CDD\|153087
NZ_CP022695.1\|WP_042325229.1\|630058_630955_+\|DNA-binding-transcriptional-regulator-YhaJ	unknown	unknown	gnl\|CDD\|176122
NZ_CP022695.1\|WP_042325233.1\|631507_632497_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223512
NZ_CP022695.1\|WP_042325220.1\|624569_625934_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP022695.1\|WP_084196668.1\|632566_633052_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168

Protein	Function_ID	Function_description	E-value
NZ_CP022695.1\|WP_042325246.1\|636191_636968_-\|transcriptional-regulator-ExuR	gnl\|CDD\|183176	PRK11523, PRK11523, transcriptional regulator ExuR.	0
NZ_CP022695.1\|WP_042325251.1\|640304_641792_+\|altronate-dehydratase	gnl\|CDD\|377287	pfam04295, GD_AH_C, D-galactarate dehydratase / Altronate hydrolase, C-terminus. Family members include the C termini of D-galactarate dehydratase (EC:4.2.1.42) which is thought to catalyze the reaction D-galactarate = 5-keto-4-deoxy-D-glucarate + H2O, and altronate hydrolase (altronic acid hydratase, EC:4.2.1.7), which catalyzes D-altronate = 2-keto-2-deoxygluconate + H2O. As purified, both enzymes are catalytically inactive in the absence of added Fe2+, Mn2+, and beta-mercaptoethanol. Synergistic activation of altronate hydrolase activity is seen in the presence of both iron and manganese ions, suggesting that the enzyme may have two ion binding sites. Mn2+ appears to be part of the enzyme active centre, but the function of the single bound Fe2+ ion is unknown. The hydratase has no Fe-S core.	0
NZ_CP022695.1\|WP_042325253.1\|641949_642504_+\|YgjV-family-protein	gnl\|CDD\|378474	pfam10688, Imp-YgjV, Bacterial inner membrane protein. This is a family of inner membrane proteins. Many of the members are YgjV protein.	1.43164e-61
NZ_CP022695.1\|WP_042325243.1\|634803_635187_-\|EnvZ/OmpR-regulon-moderator-MzrA	gnl\|CDD\|236728	PRK10629, PRK10629, EnvZ/OmpR regulon moderator MzrA.	1.37057e-71
NZ_CP022695.1\|WP_042325224.1\|627657_628971_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0
NZ_CP022695.1\|WP_042325241.1\|634286_634655_-\|DUF1090-domain-containing-protein	gnl\|CDD\|368932	pfam06476, DUF1090, Protein of unknown function (DUF1090). This family consists of several bacterial proteins of unknown function and is known as YqjC in E. coli.	1.74042e-31
NZ_CP022695.1\|WP_042325231.1\|631012_631384_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	4.47021e-39
NZ_CP022695.1\|WP_042325334.1\|633540_633945_-\|membrane-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.88071e-59
NZ_CP022695.1\|WP_042325248.1\|638877_640290_+\|glucuronate-isomerase	gnl\|CDD\|376859	pfam02614, UxaC, Glucuronate isomerase. This is a family of Glucuronate isomerases also known as D-glucuronate isomerase, uronic isomerase, uronate isomerase, or uronic acid isomerase, EC:5.3.1.12. This enzyme catalyzes the reactions: D-glucuronate <=> D-fructuronate and D-galacturonate <=> D-tagaturonate. It is not however clear where the experimental evidence for this functional assignment came from and thus this family has no literature reference.	0
NZ_CP022695.1\|WP_042325222.1\|626304_627636_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53501e-163
NZ_CP022695.1\|WP_042325226.1\|629252_629954_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	3.95311e-64
NZ_CP022695.1\|WP_042325244.1\|635190_635853_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	6.58433e-49
NZ_CP022695.1\|WP_042325218.1\|622189_624484_+\|formate-C-acetyltransferase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP022695.1\|WP_042325335.1\|637105_638407_-\|MFS-transporter	gnl\|CDD\|273326	TIGR00893, Probable_glucarate_transporter, D-galactonate transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.86884e-128
NZ_CP022695.1\|WP_042325238.1\|633947_634253_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	4.68158e-41
NZ_CP022695.1\|WP_042325229.1\|630058_630955_+\|DNA-binding-transcriptional-regulator-YhaJ	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09356e-51
NZ_CP022695.1\|WP_042325233.1\|631507_632497_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP022695.1\|WP_042325220.1\|624569_625934_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP022695.1\|WP_084196668.1\|632566_633052_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.35191e-29

>NZ_CP022695.1|WP_084196668.1|632566_633052_-|DoxX-family-protein
MILSIDSNDAEPREIALKNKISSLCGFLERRMKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVPGFLLPLTILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFIFHSNFAEGVNSLMFMKNLTIAGGFLLLGITGPGAFSIDRVLNKKW
>NZ_CP022695.1|WP_042325233.1|631507_632497_-|glutathione-S-transferase-family-protein
MGQLIDGVWHDTWYDTKSTGGKFQRSVSAFRNWLTADGTPGPSGEGGFAAEKDRYHLYVSLACPWAHRTLILRKLKGLEPFISVSVVHPLMLENGWTFDDDFPAATGDTLYQHDFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPELRNKIDELNSWIYDNVNNGVYKAGFATSQQAYDDAVENVFTALARLEQILGQHRYLTGNRLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQLPGIAETVNFEHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDSRFAE
>NZ_CP022695.1|WP_042325231.1|631012_631384_-|DUF805-domain-containing-protein
MDWYINVLCNYVGFGGRARRKEFWMFMLVNIIFAFVLGVLDKMLGWQRAGGEGVLTTIYAILVFLPNWAVQFRRLHDTNRTAWWLVLLLIPVIGWLVIILFSCQDGTPGENRFGPDPKQNERR
>NZ_CP022695.1|WP_042325229.1|630058_630955_+|DNA-binding-transcriptional-regulator-YhaJ
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLALKANTQLSVITEVLAGAWERLEQGRADIVVAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGVAVADTARERPVLTVQLLDKQARLTVSTIEDKRQALLAGLGVATMPYPLVEQDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKAWCLREIPKLFARK
>NZ_CP022695.1|WP_042325226.1|629252_629954_-|pirin-family-protein
MITTRTAKQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGASFQPRTWPKVDVLNLILEGVAEYRDSEGNHVQAQAGEALLLAAQPGISYSEHNVSKDKPLTRMQLWLDACPERENALVQKTKLTKAKQQLIASPDGENGSLQLRQQAWVHQIELNQGESLSFQLHGPRAYLQSIHGTFHAVTHDETRESLTCGDGAFIRDEANITLVADTPLRALLIDLPV
>NZ_CP022695.1|WP_042325225.1|629072_629234_-|hypothetical-protein
MSKKAKKQAPTVKSDVAQTPPAPRAFGYEEMLTELEAIVSDAEVRLAEEDEIA
>NZ_CP022695.1|WP_042325224.1|627657_628971_+|serine-dehydratase-subunit-alpha-family-protein
MSETIKNPLWSRFIRAVQEEVKPALGCTEPVSLALAAAVAASELKGSVERIDAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGDPGAGLEVLKDASAQAIADAKAMLKAGKVSVMLQQPCDDILFSRAKVYSHDGWACVTIVGGHTHIVRIETHNGVKFSQQASASGETQESPLAVLSETSLEEILAFVNTVPFNAIRFILDAARLNGALSQEGLRGNWGLHIGATMEKQCARGLLANDLSTAILIRTSAASDARMGGATLPAMSNSGSGNQGITATVPVMVVAEHFGADEEKLARALMLSHLSAIYIHHQLPRLSALCAATTAAMGAAAGMAWLVDEGRYSTISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTSVTGNEGIVAHNVEQSIANLCALACHSMQQTDKQIIEIMARKAH
>NZ_CP022695.1|WP_042325222.1|626304_627636_+|HAAAP-family-serine/threonine-permease
METATNSSVILDASAPARRAGMTESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSIIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDNPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNIGALPPMALLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSVEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGAGAGWVKVVSVILNIFAVMTAFFGVYLGFREATQGIAMNILRRKLPAEKINETLVQRGIMLFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGASLYLIIVTGLLLCVSPFLAFS
>NZ_CP022695.1|WP_042325220.1|624569_625934_+|L-serine-ammonia-lyase
MISAFDIFKPGIGPSSSHTVGPMNAGKRFIDQLVSSGRLSRTTRMSVDLYGSLSLTGKGHATDTAIMMGLAGNSPQSVNIDAIPAFIGEVARTGRLPVAEGTHVVDFPVADSIVFHEETLPRHENGMRITAWENQERLLSKTYYSIGGGFIVEEERFGQAHDVETPVPYDFHSARELLKLCEHNGLSVSGLMMQNELALRSKAEIDAGFAQIWEVMQGGIERGMNTEGVLPGPLNVPRRAVALRRLLVSSDSLSSDPMNVIDWINMFALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPLNANSIARYLLAAGAIGALYKMNASISGAEVGCQGEIGVASSMAAAGLTELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMALRRTSEPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCS
>NZ_CP022695.1|WP_042325218.1|622189_624484_+|formate-C-acetyltransferase
MKVDIDTSDMLYAEAWRGFKGTDWKEEINVRDFIQHNYTPYEGDESFLADATPATTALWEKVMAGIRIENATHAPVDFDTNIATTITAHDAGYIEQELEKIVGLQTDKPLKRALHPFGGVNMIKSSFDAYGREMDPNFEYLFTELRKTHNQGVFDAYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGIRYLVRERELQFADLQSNLEWGQSLEATIRLREELAEHRRALLQMQEMAAKYGCDISRPARNAQEAVQWVYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFNAGILTEQQAQELIDHFIMKIRMVRFLRTPEFDTLFSGDPIWATEVIGGMGLDGRTLVTKNAFRYLHTLHTMGPAPEPNLTVLWSEALPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLLDDVLDYDTVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVAADSLSAIKYATVKPVRDHNGLAVDFVIEGEYPQYGNNDERVDSIACDLVERFMKKIKVLPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEAHVEGGQHLNVNVMNKEMLLDAIEHPENYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAM
>NZ_CP022695.1|WP_042325334.1|633540_633945_-|membrane-protein
MADPHHAQGPGKSVLGIGQRIVTILVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLALALIGGIWTLRKARRSTLLRHTRHELANDRQLLEEESRER
>NZ_CP022695.1|WP_042325238.1|633947_634253_-|DUF883-domain-containing-protein
MSKENTSEHLRAELKSLADTLEEVLNSSGDKSKEELSKIRSKAERALKESRYRLGETGDAIAKQTREAAARADDYVRENPWTGVGIGAAVGVVLGVLLSRR
>NZ_CP022695.1|WP_042325241.1|634286_634655_-|DUF1090-domain-containing-protein
MKYRIAFAVSLFALSAGSYANTLCQEKEQDIQREISYAEKHNNQNRINGLKKALSEVRAHCTDSKLRADHQEKIAEQKEEIAERQRDLAEAKQKGDADKIAKRERKLAEARAELKELEARDY
>NZ_CP022695.1|WP_042325243.1|634803_635187_-|EnvZ/OmpR-regulon-moderator-MzrA
MLKPRITLKQLAWSTAFLLALSAMLLAWSAVRQQESTLAIRAIHQGASMPDGFSIWHHLDANGIRFKSITPKNDTLLITFDSSAQSAAAKAVLDKTLPHGYIIAQQDDNNQAVQWLSRLRDTSHRVG
>NZ_CP022695.1|WP_042325244.1|635190_635853_-|DedA-family-protein
MELLTQLLHALWAQDFETLANPSMIGMLYFVLFMILFLENGLLPAAFLPGDSLLVLVGVLIAKGAMGFPQTILLLTVAASLGCWLSYIQGRWLGNTRIVQNWLSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMSGLLWVLILTSLGYLLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLGGSLVVLWKKKYGNRG
>NZ_CP022695.1|WP_042325246.1|636191_636968_-|transcriptional-regulator-ExuR
MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNVSRTVVREAIIMLEVEGFVEVRKGSGIHVISNQPRHQQATDESLEFANYGPFELLQARQLIESNIAEFAATQVTKQDIMKLMEIQEQARNEKCFRDSEWDLQFHIQVALATQNSALAAIVEKMWTQRSHNPYWKKLHEHIDSRTVDNWCDDHDQILKALIRKDPHAAKLAMWQHLENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTAANATK
>NZ_CP022695.1|WP_042325335.1|637105_638407_-|MFS-transporter
MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELHISTQQYSYIIAAYSAAYTVMQPVAGYVLDILGTKIGYAMFAVLWAVFCGATALAGSWGGLALARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGVLSFVWAMSWLVFYKHPRDQKKLTDEERDYIINGQEAQHKNSTKKKMSLVQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCIVGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTSPYIAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPASDVDSGPQFDKPAAQS
>NZ_CP022695.1|WP_042325248.1|638877_640290_+|glucuronate-isomerase
MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFNNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGVTGKLLSPSTADEIWNQCNELLAQDKFSARGIMQQMNVKMVGTTDDPIDTLEHHATVAKDSSFSVKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFTDLQSALTKRLDHFAAHGCKVSDHALDVVLFAEASEAELDTILARRLAGETLNEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVQAGEAPADIQLLGEMVKNICFNNARDYFAIELN
>NZ_CP022695.1|WP_042325251.1|640304_641792_+|altronate-dehydratase
MQYIKIHVQDNVAVALADLAQGTEVTVDNHTVTLRQDVTRGHKFALSDIRKGTYVIKYGQPIGHALADIAAGEHIHAHNTRTNLSDLDEYSYQPDFQDLPAQPADRDVQIYRRASGEVGVRNELWILPTVGCVNGIARQIQNRFLKETNDAEGTDGVFLFSHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVDAFRETLGDFDPERVHFMICQHQDDEVEAGLEHLHQLYDVMRHDKREPGKLSELKFGLECGGSDGLSGITANPMLGRFSDYMIANGGTTVLTEVPEMFGAEQLLMSHCRDEETFGKLVAMVNDFKQYFIAHNQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSQVVDVLRYGERLKTHGLNLLSAPGNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQLIHGKAMPQLLDEFVDTIVDFANGKQTCNERNDFRELAIFKSGVTL
>NZ_CP022695.1|WP_042325253.1|641949_642504_+|YgjV-family-protein
MTAYWLAQGVGVLAFLIGITTFFNRDERRFRLQLAVYSATIGVHFFLMGAWPAGMSAELNTVRTLVSMRTRKLWVMALFIILTLVLGLSKLQHAMEILPVIGTLASTWALFRCKGLTVRCVMWCATACWVVHNFWLGSIGGTLIEGSFLVMNGLNIIRFWRMKRRGIDPFKIEKSVQEENPSAR

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Crispr_ID: NZ_CP022695_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022695_2

2446167-2446300

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022695_2

>merge|NZ_CP022695|2|2446167-2446300|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACAGACGCATATCAAGATGAGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP022695|2|2|2446167-2446300|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CAGACGCATATCAAGATGAGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022695.1\|WP_042319233.1\|2451487_2452420_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP022695.1\|WP_094465403.1\|2443238_2444300_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022695.1\|WP_042319258.1\|2437584_2438403_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP022695.1\|WP_042319252.1\|2439468_2439660_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022695.1\|WP_094465405.1\|2450170_2451376_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP022695.1\|WP_042319238.1\|2448730_2449879_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP022695.1\|WP_042319232.1\|2452416_2453442_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP022695.1\|WP_042319248.1\|2441721_2442519_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293813
NZ_CP022695.1\|WP_042319231.1\|2453994_2455161_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP022695.1\|WP_167382409.1\|2436805_2437588_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP022695.1\|WP_042319240.1\|2448050_2448692_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP022695.1\|WP_042319251.1\|2440002_2441613_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP022695.1\|WP_042319230.1\|2455207_2455789_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP022695.1\|WP_042320052.1\|2446458_2447832_-\|MdtK-family-multidrug-efflux-MATE-transporter	unknown	unknown	gnl\|CDD\|234981
NZ_CP022695.1\|WP_042319242.1\|2444359_2446084_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197270
NZ_CP022695.1\|WP_094465401.1\|2439778_2439919_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022695.1\|WP_042319227.1\|2455915_2456749_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|223862
NZ_CP022695.1\|WP_125368037.1\|2453735_2453825_+\|YnhF-family-membrane-protein	unknown	unknown	gnl\|CDD\|341227
NZ_CP022695.1\|WP_042319246.1\|2442556_2442862_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP022695.1\|WP_042319255.1\|2438404_2439238_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270407

Protein	Function_ID	Function_description	E-value
NZ_CP022695.1\|WP_042319233.1\|2451487_2452420_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP022695.1\|WP_042319231.1\|2453994_2455161_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.11836e-99
NZ_CP022695.1\|WP_042319258.1\|2437584_2438403_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.98962e-138
NZ_CP022695.1\|WP_094465405.1\|2450170_2451376_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP022695.1\|WP_042319238.1\|2448730_2449879_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP022695.1\|WP_042319232.1\|2452416_2453442_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP022695.1\|WP_042319248.1\|2441721_2442519_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293813	cd07727, YmaE-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YmaE and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YmaE and Nostoc all1228 proteins.Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry. .	3.83562e-48
NZ_CP022695.1\|WP_167382409.1\|2436805_2437588_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.88174e-52
NZ_CP022695.1\|WP_042319240.1\|2448050_2448692_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	5.19829e-124
NZ_CP022695.1\|WP_042319251.1\|2440002_2441613_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP022695.1\|WP_042319230.1\|2455207_2455789_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.75999e-138
NZ_CP022695.1\|WP_042320052.1\|2446458_2447832_-\|MdtK-family-multidrug-efflux-MATE-transporter	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP022695.1\|WP_042319242.1\|2444359_2446084_+\|hypothetical-protein	gnl\|CDD\|197270	cd09173, PLDc_Nuc_like_unchar1_2, Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium. Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins, which show high sequence homology to the endonuclease from Salmonella typhimurium and vertebrate phospholipase D6. Nuc and PLD6 belong to the phospholipase D (PLD) superfamily. They contain a short conserved sequence motif, the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue), which characterizes the PLD superfamily and is essential for catalysis. Nuc and PLD6 utilize a two-step mechanism to cleave phosphodiester bonds: Upon substrate binding, the bond is first attacked by a histidine residue from one HKD motif to form a covalent phosphohistidine intermediate, which is then hydrolyzed by water with the aid of a second histidine residue from the other HKD motif in the opposite subunit. However, proteins in this subfamily have two HKD motifs in a single polypeptide chain.	1.75625e-36
NZ_CP022695.1\|WP_042319227.1\|2455915_2456749_-\|C40-family-peptidase	gnl\|CDD\|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	4.78348e-45
NZ_CP022695.1\|WP_125368037.1\|2453735_2453825_+\|YnhF-family-membrane-protein	gnl\|CDD\|341227	PRK14756, small_mem_YnhF, YnhF family membrane protein; Validated.	0.00783365
NZ_CP022695.1\|WP_042319246.1\|2442556_2442862_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	9.97581e-61
NZ_CP022695.1\|WP_042319255.1\|2438404_2439238_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270407	cd13689, PBP2_BsGlnH, Substrate binding domain of ABC glutamine transporter from Bacillus subtilis; the type 2 periplasmic-bindig protein fold. This group includes periplasmic glutamine-binding domain GlnP from Bacillus subtilis and its related proteins. The GlnP domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.07576e-109

>NZ_CP022695.1|WP_042319242.1|2444359_2446084_+|hypothetical-protein
MSGYTCYTTDNGFHFKLWRGERMVLLGFDVDDPEPDFVGFAIKVRPPNSHAFTYLKNRIAFDYSAVTVTGDRLFATNIAPLQRFRWIHFPWQPVTGIYHYQATKMHMDPDGRLREGITLENSIELSPVTYDGIVDIGFTRNFASSQAYRDQFNNNADIIPGQGEDGLNFKLRDDVKNNRDETVYDWLGFEAKTLIDTFIQEVSDNPELRLDIMAYDLNLPDLVKKLEAIGPRLRAVIDDSSKKEKGVLKGHGASNSSESMAAERLAAAGAKVTRTRFFNLQHHKVLIQRDKQNQAVKVLCGSTNFSFRGLYIQANNVLVFHSSGVAASFGQMFDEAFTEPKAFRHSPLSQSIQTIKHANGPTVNVSYSPHLATSLSLDPVVNAINQASSSVFYSVAFLNLMQESPVGVALSKLLTRPVFSYGTVDTAGKLQVIKPDGTLAVADFAYLAKKAPEPFRTEWAGGGGINVHHKFVVTDFNLPGAKVFTGSSNLAPSGEKDNGDHLIMIEDQKIATAYVIEAIRVFDHLQFRQRMQDAVNIQVLKLLKPTAISGQPAWFTRFYIADSQAKNDRLLFSH
>NZ_CP022695.1|WP_094465403.1|2443238_2444300_+|hypothetical-protein
MRALLIFPVSALLLLNPTTELQAAPSAIVPVQPGVATAIARAPCIRPPEASSVGKIAVEKDGALYVASIIVPAAQQVPFLVTIDTGETNLVPCPGDKPLQIQIIPQQQTQISSASLQQAFVVLMATFVLALLMESAFALLFNWRLFQAVVVGRAWRTPIMLVGSWLVVSSFKLDLMAELFSAYRGLTVAGDVFTEILTAMIVSGGSVGVNKILTGLGFRSALPRQDPNAERDSLAQNEAWVSLDISAVLPGRRLSVEMLEDAAPVGTAPTLAIFTPPGEGQLKAIMFPSRGRLPASGGMRVTALDKLYYFAIRDLNSNQLYDVNGNKISDIRSSAPYCFAARAIVDFSVVRLQ
>NZ_CP022695.1|WP_042319246.1|2442556_2442862_-|monooxygenase
MPKLLQLHFAFHGPFGQEMADQLGELAASINQEPGFLWKVWTESEQNQEAGGIYLFENEETALAYLDKHTARLKNLGVEEVIAKIFDVNIPLSKINKAKFD
>NZ_CP022695.1|WP_042319248.1|2441721_2442519_+|MBL-fold-metallo-hydrolase
MITLCKACGTSYDDSQRAVEGCKICEDERQYVPVSGQAWIGFDELILTHTNKWQQHTPQLFSLTTVPSFAINQRAFLLRTPVGNVLWDCIANLDPATRTLIQALGGLSAIAISHPHYYTTMQDWAKTFDAPVWLHAADRDWVMRDSPWIRLWEGEEHALLPGVTLLRLGGHFAGGTVLYQDEGEGTILTGDILQITPGADAVSFMWSYPNMLPLSAKTVAGITRRLEGVKFASLYGAFEGQNRVGDAHEIVQRAGAKYLSCLASR
>NZ_CP022695.1|WP_042319251.1|2440002_2441613_-|FAD-NAD(P)-binding-protein
MKKIAIIGAGPTGVYTFFSLLKEEQPLEIAVFERGSKAGIGMPYSHSENTPMMLSNIASIEVPPLFDTWLEWLQAQEAQYLAHYGVKKEALHQRQFLPRILLGDYFRAQFLQAVSRAESRGFKVMVYESCEVTDVAADPTGVQLWTDQHAEPLHVDLAIIATGHVWPDNDESTHAFYPSPWSGLMEADVPATRVGILGTSLSGLDAAMAVAIQHGTFHETEGNQVHFSLDKASEGLEITLMSRSGILPEADFYCPIPYEPLACVTEEAITREIDAGPAGLLDRVFSLMQQELALADPKWAEQISLFSLDADSFSVALFADRMHSDPFEWAAANLKEVDANKRDKRTVAWRYTLLRLHERVQDIVAHLDEKDSKRFSSGLARVFIDNYAAIPSESIRRMLALHAAGILHILALGQDYEKEIKADRTEITTRNDRLTFDVFIDARGQKPLKTADLPFPRLRSQLLSCGDEIPEVGDDYTLQASESVRGRIAFGALPYLMHDRPFIQGLVACQEIGTAMARAVSKPATRLRRRLSLHDW
>NZ_CP022695.1|WP_094465401.1|2439778_2439919_-|hypothetical-protein
MEIDLDNLVFNGLEEAQERNAERLEEADKKAESVISDDDCGDACKI
>NZ_CP022695.1|WP_042319252.1|2439468_2439660_+|hypothetical-protein
MEKMKMRRVRFWAHDAIAPDKTRQPGAEFNLQRVVESILPVASLYGVDIANIDPEWFRDQTTR
>NZ_CP022695.1|WP_042319255.1|2438404_2439238_-|ABC-transporter-substrate-binding-protein
MMATKIYSSKKTILALGVMLATSFISAQVQADQLADIKAAGVVKVATFDANPPFGSVDPKTHQIVGYDVDFAQALAKSLGVKLELVATNPANRIPLLQSGKADLIVADITITPERAQVIDFSVPYFVTGQQFLVPVSSPDKLDEYSRARIGAVKGTTGEQALHQRFPQSRVLAYDDIPLAFTALRNGNVQAITQDSTILAGLLGGAPDKAQFKILPDLLSKEEIGVGVKKGETALLKAVNDELLRLETSGQASKIYDVWFGPETKNPQPRAFKIEAR
>NZ_CP022695.1|WP_042319258.1|2437584_2438403_-|amino-acid-ABC-transporter-ATP-binding-protein
MLAGLFTPSAAQAADFSQLHQARVVLRDVVKTYGDHRVLNGVNLTVEPGEVVTILGPSGSGKSTLIRLINQLESLSGGDILIDDRPVGRLKGAALRQLRSRIGFVFQQFNLYAHLTAQQNITLALEYVHGWNKTDATLRAYALLEQVGLEEKAGAYPAQLSGGQQQRVAIARALASSPQIILFDEPTSALDPEMIGEVLQVMKRLAHSGITMIVVTHEMHFAREIADRVVFIDGGDILEVASPEAFFTRPQHPRTQRFLQKVLDPLHQELSR
>NZ_CP022695.1|WP_167382409.1|2436805_2437588_-|ABC-transporter-permease-subunit
MMPSMDWQGVLTGLPLQWILSGFLTTLWVSAAGIFLATLLAIILLALRLSGHITGRRLVAGWVSLFRNTPLLVQLLFWYFAGWNLLPRGFVDFVNAEHSWSILPGNVWWLTPEFLCSAWGLGVFTSAFLVEEIASGLQAVSDGQREAAVSQGFSPWLTFRYILLPQGLTNAWQPVVGQYLNLMKLSSLASGIGFAELTYQVRQIESYNAHALEAFAVGTVLYLFTGVALGLLLTHLGPAPRQEKKPRVRRVRFRSPQHDR
>NZ_CP022695.1|WP_042320052.1|2446458_2447832_-|MdtK-family-multidrug-efflux-MATE-transporter
MQKYISEARQLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSLLIMVVLWNAGYIIRAMHNIDPVLADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFLGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFCAMLWYVKHARSMRDIRNEQRFSKPDNAVMKRLVQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLGVGVCMACFTAIFTVSLREHIALLYNDNPEVVTLAAQLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFFITFTAYWVLGLPSGYVLALTDLVVDRMGPAGFWMGFIIGLTSAAIMMMLRMRFLQRQPSTVILQRAAR
>NZ_CP022695.1|WP_042319240.1|2448050_2448692_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPEYMLDALETGASVAHNGCCLTVTEIHGNRISFDLMKETLRITNLGDLKIGDQVNVERAAKFSDEIGGHLMSGHIMTTAEVSKILTSENNRQIWFKVQDPTLMKYILYKGFIGIDGISLTVGEVTATRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAAREAAVNNTASDM
>NZ_CP022695.1|WP_042319238.1|2448730_2449879_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDDWYRITNELLSRAGIAINGSSPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDQFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQNKKRAWIVGKEHYDLGNDLFSRMLDPYMQYSCAYWKDADTLEEAQQAKLRLICEKLQLQPGMRVLDIGCGWGGLSHYMATKYGVSVVGVTISAEQQKMAQTRCAGLDVSILLQDYRDLHDRFDRIVSVGMFEHVGPKNYPTYFEVVDRNLKPEGLFLLHTIGSKKTDNNVDPWINKYIFPNGCLPSVRQIANASEAHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYTERFKRMFSYYLNACAGAFRARDIQLWQVVFSRGVEDGLRVAR
>NZ_CP022695.1|WP_094465405.1|2450170_2451376_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQSDLQTPASAVSASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSIFALGSLGMLWVESATGLLVLRFIQAVGVCAATVIWQALVTDYYPSPRINRIFATIMPLVGLSPALAPLLGSWILTHLSWQAIFATLFIITLLLMVPALFLKPTSRARDDSKDKLTFTTLLRAKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGQQLLPWLLVIYALSVVATWAASFIHHITLAEILIPFCVMAIANGAIYPIVVAQALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAGVGYKMQLQPSDASEQHEDRGIAHSESH
>NZ_CP022695.1|WP_042319233.1|2451487_2452420_+|LysR-family-transcriptional-regulator
MWSEYALEVVDAVARNGSFSSAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVVLTPAGAWFLKEGRSVIKKMQITRQQCQQIANGWRGQLPIAVDNIVRPERTRQLIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATQAIPVGGRYTFRDMGKLSWCCVVASTHPLAAMSGPLSDDTLRNWPSLVLEDTSRTLPKRVTWLLDNQKRVVVPDWDSSATCISAGLCVGMVPTHFAKPYLNKRQWVALNLENPFPDAGCCLTWQQNDMSPALIWLLDYLGDSETLNKEWLREPDETPAEDV
>NZ_CP022695.1|WP_042319232.1|2452416_2453442_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAPYFAEIIEAVEKNCFQKGYTLILGNVWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPDPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFEGGYMAGRYLVERGHREIGVIPGLMERNTGAGRLAGFMKAMDEALIKVPENWIVQGDFEPESGYRAMQQILSQAHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARFFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFRDYRR
>NZ_CP022695.1|WP_125368037.1|2453735_2453825_+|YnhF-family-membrane-protein
MSTDLKFSLVTTFIVLALIVAGGLTAAMH
>NZ_CP022695.1|WP_042319231.1|2453994_2455161_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRGRRNALIFLMAIFTLGNVLSAISPDYTTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTIANIGGVPAATWLGETIGWRMSFMATAGLGVISMLSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPAFVTGMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMMIMLAIPLLAQNELGAAIGMVVWGAATFAVVPPLQMRVMRVAHEAPGLSSSVNIGAFNLGNALGAAAGGAVISGGLGYSFVPVMGAIVAGMALLLVFVSARKQPEQVCVAG
>NZ_CP022695.1|WP_042319230.1|2455207_2455789_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETLEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIVRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKLADAIAASFGSFSEFKAQFTDAAIKNFGSGWTWLVKGKDGKLAIVSTSNAGTPLTTDATPLMTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNFAA
>NZ_CP022695.1|WP_042319227.1|2455915_2456749_-|C40-family-peptidase
MARINRLSLTLCALLFTTIPFMPMAHASKQARDASALAHNKKASDKKKSTATAKKTHKTSQKTVKKTTSKTSTKTASSSKKKLTAPAKASKTANRKGKSVATKKTASVTWSEKCTPRKGHKPTCVKVKNTGPGKIADAHKVKVQKATSTAMNKLMSQIGKPYRWGGTSPRTGFDCSGLVYYAYKDLVKFRIPRTANEMYHLRDAAPIDREELKNGDLVFFRTQGRGTADHVGVYVGNGKFIQSPRSGQEIQITSLSEDYWQRHYVGARRVMTPKTIR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022695_1	1.1\|633214\|28\|NZ_CP022695\|CRISPRCasFinder	633214-633241	28	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	107623-107650	4	0.857
NZ_CP022695_1	1.1\|633214\|28\|NZ_CP022695\|CRISPRCasFinder	633214-633241	28	NZ_CP029339	Streptomyces sp. SM17 plasmid pSM17A, complete sequence	135607-135634	6	0.786
NZ_CP022695_1	1.1\|633214\|28\|NZ_CP022695\|CRISPRCasFinder	633214-633241	28	NC_010311	Streptomyces sp. HK1 plasmid pSHK1, complete sequence	34302-34329	6	0.786

1. spacer 1.1|633214|28|NZ_CP022695|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 4, identity: 0.857

agtaggaggaggtcgagtgcgtaggcct	CRISPR spacer
cgcaggaggaggtcgagcgcgtcggcct	Protospacer
 *.**************.**** *****

2. spacer 1.1|633214|28|NZ_CP022695|CRISPRCasFinder matches to NZ_CP029339 (Streptomyces sp. SM17 plasmid pSM17A, complete sequence) position: , mismatch: 6, identity: 0.786

agtaggaggaggtcgagtgcgtaggcct	CRISPR spacer
atcaggaggaggccgagtgcgtcggcgc	Protospacer
* .*********.********* *** .

3. spacer 1.1|633214|28|NZ_CP022695|CRISPRCasFinder matches to NC_010311 (Streptomyces sp. HK1 plasmid pSHK1, complete sequence) position: , mismatch: 6, identity: 0.786

agtaggaggaggtcgagtgcgtaggcct	CRISPR spacer
atcaggaggaggccgagtgcgtcggcgc	Protospacer
* .*********.********* *** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

530338 : 538017

Thermobifida_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042291907.1\|530338_531193_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.4e-05	28.4
WP_042325036.1\|531226_531718_-	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_042325038.1\|531833_532121_-	ribosome hibernation promoting factor	A0A0M7QCF2	Escherichia_phage	5.5e-10	43.2
WP_042325041.1\|532143_533577_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_042325043.1\|533624_534350_-	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.4e-22	28.4
WP_042325045.1\|534356_534911_-	lipopolysaccharide ABC transporter substrate-binding protein LptA	NA	NA	NA	NA
WP_042325047.1\|534879_535455_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_042325049.1\|535451_536018_-	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	1.4e-54	76.5
WP_042325051.1\|536038_537025_-	arabinose-5-phosphate isomerase KdsD	A0A2P0VNK5	Tetraselmis_virus	1.1e-38	31.5
WP_042325053.1\|537039_538017_-	calcium/sodium antiporter	A0A2D1GNI8	Pseudoalteromonas_phage	9.6e-06	21.7

DBSCAN-SWA_2

671373 : 713018

Salmonella_phage(84.62%)

integrase,head,terminase,tail,tRNA,portal,lysis,plate,capsid

attL 670398:670444|attR 703727:703773

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
670398:670444	attL	NA	NA	NA	NA
WP_094464751.1\|671373_672429_-\|integrase	tyrosine-type recombinase/integrase	F1BUS9	Erwinia_phage	8.0e-115	59.1
WP_094464753.1\|672655_673270_-	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.2e-38	44.6
WP_015386350.1\|673371_673608_+	hypothetical protein	NA	NA	NA	NA
WP_094464755.1\|673642_674152_+	phage regulatory CII family protein	A0A1S6L008	Salmonella_phage	3.9e-83	92.9
WP_032442472.1\|674159_674360_+	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	6.7e-31	92.4
WP_048971665.1\|674323_674665_+	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	9.0e-52	87.6
WP_063867217.1\|674732_674966_+	DUF2732 domain-containing protein	E5G6L6	Salmonella_phage	9.2e-24	80.5
WP_013098805.1\|674965_675193_+	TraR/DksA family transcriptional regulator	A0A1S6L007	Salmonella_phage	5.1e-35	93.3
WP_094464757.1\|675189_676047_+	DNA adenine methylase	A0A1S6L011	Salmonella_phage	1.1e-154	94.7
WP_094464759.1\|676037_678446_+	replication endonuclease	A0A1S6L028	Salmonella_phage	0.0e+00	96.1
WP_046669924.1\|678464_678692_-	hypothetical protein	NA	NA	NA	NA
WP_046669925.1\|678829_679018_+	hypothetical protein	A0A1S6L006	Salmonella_phage	3.3e-24	90.3
WP_052946580.1\|679289_679472_-	hypothetical protein	NA	NA	NA	NA
WP_094464761.1\|680337_681318_+	DGQHR domain-containing protein	NA	NA	NA	NA
WP_094464763.1\|681314_682259_+	hypothetical protein	NA	NA	NA	NA
WP_094464765.1\|682274_683309_-\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	2.6e-179	94.4
WP_094464767.1\|683308_685075_-\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	94.9
WP_094464769.1\|685215_686049_+\|capsid	GPO family capsid scaffolding protein	E5G6M5	Salmonella_phage	2.7e-126	96.8
WP_094464771.1\|686065_687130_+\|capsid	phage major capsid protein, P2 family	A0A1S6KZZ3	Salmonella_phage	4.6e-195	98.3
WP_094464773.1\|687133_687784_+\|terminase	terminase endonuclease subunit	A0A1S6KZX1	Salmonella_phage	1.1e-114	99.1
WP_094464775.1\|687877_688342_+\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	1.2e-83	96.8
WP_094464777.1\|688341_688545_+\|tail	phage tail protein	E5G6M9	Salmonella_phage	1.1e-33	98.5
WP_001397650.1\|688548_688764_+	membrane protein	E5G6N0	Salmonella_phage	8.5e-32	97.2
WP_094464779.1\|688744_689260_+	lysozyme	E5G6N1	Salmonella_phage	3.0e-75	78.8
WP_167382379.1\|689256_689685_+\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	9.2e-62	91.5
WP_094464781.1\|689780_690212_+\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	2.1e-74	96.5
WP_094464783.1\|690204_690654_+	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	8.7e-63	85.1
WP_094464785.1\|690655_691351_-	hypothetical protein	NA	NA	NA	NA
WP_094465824.1\|691451_692030_+\|plate	phage baseplate assembly protein V	A0A1S6KZX7	Salmonella_phage	5.5e-102	93.8
WP_094464787.1\|692026_692386_+\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	3.1e-55	92.4
WP_094464789.1\|692372_693281_+\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	1.8e-144	91.7
WP_094464791.1\|693273_693879_+\|tail	phage tail protein I	E5G6N9	Salmonella_phage	8.6e-114	96.0
WP_094464793.1\|693875_695093_+\|tail	phage tail protein	A0A1S6KZZ8	Salmonella_phage	5.0e-121	71.3
WP_094464795.1\|695079_695271_+	hypothetical protein	NA	NA	NA	NA
WP_094464797.1\|695376_696444_-	acyltransferase family protein	NA	NA	NA	NA
WP_094464799.1\|696749_697922_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	6.2e-209	92.6
WP_094464801.1\|697931_698447_+\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	3.3e-90	97.7
WP_060773291.1\|698501_698804_+\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	2.3e-43	96.0
WP_094464803.1\|698818_698938_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.6e-14	92.3
WP_094464805.1\|698930_701723_+\|tail	phage tail tape measure protein	A0A1S6L010	Salmonella_phage	7.1e-296	72.7
WP_094464807.1\|701719_702205_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	1.5e-71	87.6
WP_094464809.1\|702201_703302_+	phage late control D family protein	E5G6Q3	Salmonella_phage	2.7e-190	92.3
WP_024146528.1\|703371_703590_+	DNA-binding transcriptional regulator	Q53ZE7	Salmonella_virus	4.9e-27	75.0
WP_042324328.1\|703926_704433_+	G/U mismatch-specific DNA glycosylase	NA	NA	NA	NA
703727:703773	attR	NA	NA	NA	NA
WP_042324326.1\|704463_706461_-	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	3.2e-08	27.2
WP_094464811.1\|706471_707521_-	YncE family protein	NA	NA	NA	NA
WP_042324322.1\|707682_709530_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	8.4e-35	33.7
WP_042324320.1\|709700_711446_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.3e-77	39.1
WP_001144069.1\|711561_711777_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_042324318.1\|712004_713018_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.6e-107	59.2

DBSCAN-SWA_3

1359755 : 1393924

Cronobacter_phage(58.62%)

integrase,head,terminase,tail,tRNA,portal,holin,capsid

attL 1374072:1374087|attR 1398890:1398905

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042324410.1\|1359755_1360235_-\|tRNA	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK	NA	NA	NA	NA
WP_042324407.1\|1360436_1361231_-	hypothetical protein	NA	NA	NA	NA
WP_042324405.1\|1361372_1363874_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	7.9e-113	38.2
WP_094465010.1\|1364134_1364644_+	hypothetical protein	NA	NA	NA	NA
WP_094465012.1\|1365152_1366877_-	hypothetical protein	F1BUJ7	Cronobacter_phage	1.1e-169	60.7
WP_094465014.1\|1366880_1367426_-	hypothetical protein	F1BUJ9	Cronobacter_phage	8.7e-41	53.3
WP_094465016.1\|1367397_1368120_-	hypothetical protein	F1BUK1	Cronobacter_phage	9.2e-46	42.4
WP_094465017.1\|1368175_1368526_-	hypothetical protein	N0DPE7	Edwardsiella_phage	1.6e-08	36.2
WP_094465019.1\|1370316_1370907_-	hypothetical protein	F1BUK5	Cronobacter_phage	3.4e-75	65.8
WP_094465021.1\|1370899_1372084_-	hypothetical protein	F1BUK6	Cronobacter_phage	2.0e-159	71.0
WP_094465023.1\|1372076_1372412_-	DUF2590 family protein	F1BUK8	Cronobacter_phage	1.6e-29	58.7
WP_094465025.1\|1372408_1374481_-\|tail	phage tail tape measure protein	F1BUK9	Cronobacter_phage	1.1e-147	42.6
1374072:1374087	attL	NA	NA	NA	NA
WP_086512667.1\|1374482_1374662_-	hypothetical protein	A5X9I8	Aeromonas_virus	6.4e-09	65.2
WP_094465027.1\|1374670_1374940_-	hypothetical protein	NA	NA	NA	NA
WP_094465029.1\|1375042_1375426_-	hypothetical protein	A0A2I6PD12	Escherichia_phage	1.1e-05	38.4
WP_094465031.1\|1375425_1375764_-	M15 family metallopeptidase	F1BUL3	Cronobacter_phage	6.2e-45	87.1
WP_086512662.1\|1375760_1376063_-\|holin	holin	NA	NA	NA	NA
WP_094465033.1\|1376067_1376523_-	DUF2597 family protein	A5X9I1	Aeromonas_virus	2.3e-39	53.0
WP_094465035.1\|1376525_1377668_-	DUF2586 family protein	F1BUL5	Cronobacter_phage	5.6e-130	61.6
WP_139155876.1\|1377670_1378327_-	hypothetical protein	F1BUL6	Cronobacter_phage	3.3e-66	58.9
WP_094465039.1\|1378362_1378839_-\|tail	phage tail protein	NA	NA	NA	NA
WP_094465041.1\|1378835_1379309_-\|head	head completion/stabilization protein	F1BUL8	Cronobacter_phage	4.5e-33	56.5
WP_094465043.1\|1379412_1380117_-\|terminase	terminase	F1BUM0	Cronobacter_phage	4.9e-68	56.3
WP_094465045.1\|1380119_1381151_-\|capsid	phage major capsid protein, P2 family	F1BUM2	Cronobacter_phage	3.1e-95	52.9
WP_094465047.1\|1381175_1382240_-\|capsid	phage capsid protein	F1BUM4	Cronobacter_phage	2.2e-32	41.4
WP_094465049.1\|1382417_1384229_+	hypothetical protein	F1BUM5	Cronobacter_phage	1.4e-188	55.7
WP_094465051.1\|1384225_1385287_+\|portal	phage portal protein	F1BUM7	Cronobacter_phage	1.2e-121	62.0
WP_086512651.1\|1385334_1385610_+	ogr/Delta-like zinc finger family protein	F1BUM8	Cronobacter_phage	6.2e-27	59.6
WP_094465053.1\|1385637_1386360_-	DNA adenine methylase	A0A0M4S5U3	Salmonella_phage	4.6e-90	70.2
WP_094465055.1\|1386581_1389191_-	replication endonuclease	E5G6L9	Salmonella_phage	2.0e-127	38.5
WP_094465057.1\|1389199_1389463_-	hypothetical protein	NA	NA	NA	NA
WP_094465059.1\|1389462_1390452_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A0M4QWR0	Salmonella_phage	8.3e-106	61.4
WP_094465061.1\|1390522_1390912_-	hypothetical protein	NA	NA	NA	NA
WP_086512645.1\|1390928_1391159_-	DUF2724 domain-containing protein	A0A0M4S6M9	Salmonella_phage	5.2e-11	48.5
WP_086513021.1\|1391155_1391491_-	hypothetical protein	NA	NA	NA	NA
WP_086512644.1\|1391718_1392018_+	helix-turn-helix transcriptional regulator	Q1JS29	Enterobacteria_phage	1.3e-25	54.5
WP_086512643.1\|1392087_1393110_+\|integrase	tyrosine-type recombinase/integrase	A0A0F7LA05	Escherichia_phage	1.1e-92	49.2
WP_042324404.1\|1393210_1393924_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	3.7e-15	38.2
1398890:1398905	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1888661 : 1986514

105

Salmonella_phage(20.93%)

integrase,head,terminase,protease,tail,portal,holin,capsid,plate

attL 1899514:1899529|attR 1913904:1913919

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042319993.1\|1888661_1890422_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_042319990.1\|1890607_1891060_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_042319987.1\|1891143_1892199_-	porin OmpA	NA	NA	NA	NA
WP_042319986.1\|1892555_1893065_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_042319983.1\|1893282_1893912_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_094465132.1\|1893865_1896028_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_042319980.1\|1896046_1896493_-	YccF domain-containing protein	NA	NA	NA	NA
WP_042319976.1\|1896616_1898671_+	DNA helicase IV	A7KV33	Bacillus_phage	1.4e-19	27.9
WP_042319974.1\|1898702_1899161_-	methylglyoxal synthase	NA	NA	NA	NA
WP_042319972.1\|1899254_1899917_-	DUF2057 family protein	NA	NA	NA	NA
1899514:1899529	attL	NA	NA	NA	NA
WP_042319968.1\|1900089_1900503_+	CoA-binding protein	NA	NA	NA	NA
WP_042319966.1\|1900548_1900866_-	heat shock protein HspQ	NA	NA	NA	NA
WP_042319964.1\|1900923_1902114_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_042319962.1\|1902208_1902490_+	acylphosphatase	NA	NA	NA	NA
WP_042319960.1\|1902486_1902816_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_012905355.1\|1902906_1903566_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	4.4e-47	54.9
WP_061070694.1\|1904030_1905059_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	5.6e-81	50.3
WP_094465134.1\|1904997_1905276_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_094465136.1\|1905345_1907628_-	exonuclease	S4TNL0	Salmonella_phage	3.3e-113	46.0
WP_094465842.1\|1907769_1908096_-	transcriptional regulator	NA	NA	NA	NA
WP_043001146.1\|1908107_1908446_-	hypothetical protein	NA	NA	NA	NA
WP_046402092.1\|1908606_1908798_-	DUF1482 family protein	NA	NA	NA	NA
WP_167382385.1\|1908794_1908992_-	hypothetical protein	NA	NA	NA	NA
WP_094465140.1\|1909425_1909833_-	helix-turn-helix domain-containing protein	H6WRX4	Salmonella_phage	4.0e-30	52.3
WP_044266820.1\|1909963_1910191_+	Cro/Cl family transcriptional regulator	H6WRX5	Salmonella_phage	3.8e-30	78.7
WP_094465142.1\|1910193_1910748_+	hypothetical protein	M9NZI6	Enterobacteria_phage	2.0e-16	33.7
WP_167382406.1\|1910819_1911902_+	hypothetical protein	A0A0U2RT81	Escherichia_phage	1.1e-45	50.8
WP_139155853.1\|1911813_1912359_+	replication protein	A0A0U2JGJ0	Escherichia_phage	1.6e-66	73.2
WP_094465144.1\|1912374_1913091_+	hypothetical protein	NA	NA	NA	NA
WP_094465146.1\|1913087_1913294_+	hypothetical protein	K7PLX1	Enterobacteria_phage	9.0e-15	63.1
WP_094465148.1\|1913290_1913524_+	hypothetical protein	S4TVX5	Salmonella_phage	4.7e-12	45.5
WP_094465150.1\|1913520_1914009_+	hypothetical protein	NA	NA	NA	NA
1913904:1913919	attR	NA	NA	NA	NA
WP_094465152.1\|1914005_1914842_+	DNA adenine methylase	Q5QF26	Pseudomonas_virus	3.9e-72	51.1
WP_094465154.1\|1914923_1915796_-	hypothetical protein	NA	NA	NA	NA
WP_139155854.1\|1915792_1916842_-	AAA family ATPase	A0A1X9IGI7	Lactococcus_phage	6.5e-16	28.9
WP_094465158.1\|1916852_1917938_-	hypothetical protein	Q684B3	Sulfolobus_virus	2.0e-12	26.2
WP_044266846.1\|1918149_1918383_+	DinI-like family protein	K7PM44	Enterobacteria_phage	3.5e-31	84.4
WP_043001133.1\|1918426_1918672_+	hypothetical protein	H6WRY6	Salmonella_phage	6.3e-23	65.3
WP_094465160.1\|1918797_1918998_+	hypothetical protein	H6WRY8	Salmonella_phage	7.9e-16	59.1
WP_043001131.1\|1919000_1919381_+	RusA family crossover junction endodeoxyribonuclease	G8C7V6	Escherichia_phage	4.4e-47	71.9
WP_094465162.1\|1919356_1920391_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	2.2e-101	52.6
WP_094465164.1\|1920404_1921004_+	hypothetical protein	H9C175	Pectobacterium_phage	4.9e-77	67.3
WP_094465166.1\|1921844_1922237_+	hypothetical protein	K7PHB9	Enterobacterial_phage	1.6e-60	96.2
WP_044268894.1\|1922223_1922505_+\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.4e-34	77.2
WP_094465168.1\|1922661_1923276_+	glycoside hydrolase family 19 protein	Q8HA86	Salmonella_phage	6.1e-91	80.9
WP_044266511.1\|1923282_1923558_+	hypothetical protein	G8C7W1	Escherichia_phage	3.0e-21	66.3
WP_044266513.1\|1923760_1924051_+	hypothetical protein	NA	NA	NA	NA
WP_094465170.1\|1924166_1924808_+	hypothetical protein	NA	NA	NA	NA
WP_094465848.1\|1924842_1925346_-	hypothetical protein	NA	NA	NA	NA
WP_094465172.1\|1925636_1926206_+	hypothetical protein	NA	NA	NA	NA
WP_094465174.1\|1926147_1928271_+\|terminase	terminase	A0A2K9V3X4	Faecalibacterium_phage	1.2e-96	35.8
WP_000483309.1\|1928279_1928543_+	hypothetical protein	NA	NA	NA	NA
WP_094465176.1\|1928542_1930180_+\|portal	phage portal protein	A0A291AUL8	Sinorhizobium_phage	3.3e-91	35.2
WP_094465178.1\|1930176_1931043_+	S49 family peptidase	A0A2D1GN02	Marinobacter_phage	2.8e-49	37.6
WP_094465179.1\|1931044_1931635_+	hypothetical protein	NA	NA	NA	NA
WP_094465181.1\|1931634_1932039_+\|head	head decoration protein	NA	NA	NA	NA
WP_094465183.1\|1932137_1933187_+\|capsid	major capsid protein	V5Q8G6	Xylella_phage	1.1e-50	33.7
WP_094465185.1\|1933158_1933569_+	hypothetical protein	NA	NA	NA	NA
WP_094465187.1\|1933573_1933933_+	hypothetical protein	NA	NA	NA	NA
WP_094465189.1\|1933929_1934475_+	ATP-binding protein	NA	NA	NA	NA
WP_094465191.1\|1934478_1934676_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_094465194.1\|1934672_1936175_+\|tail	phage tail protein	B5TK67	Pseudomonas_phage	3.8e-102	42.9
WP_000896638.1\|1936178_1936550_+\|tail	phage tail protein	NA	NA	NA	NA
WP_094465197.1\|1936551_1936830_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_167382386.1\|1936971_1938777_+	transglycosylase SLT domain-containing protein	I6ZXX9	Escherichia_phage	3.2e-31	49.0
WP_094465199.1\|1938846_1940247_+	DNA circularization protein	NA	NA	NA	NA
WP_094465201.1\|1940243_1941329_+\|tail	phage tail protein	M1PVV2	Vibrio_phage	6.2e-46	33.2
WP_094465203.1\|1941325_1941910_+\|plate	baseplate assembly protein	A0A077KAY0	Edwardsiella_phage	2.3e-07	34.1
WP_094465205.1\|1941906_1942356_+	hypothetical protein	A0A0C4UR04	Shigella_phage	2.5e-17	47.7
WP_094465207.1\|1942345_1943488_+\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	1.0e-27	29.4
WP_094465209.1\|1943484_1944078_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_094465211.1\|1944796_1944982_+	hypothetical protein	NA	NA	NA	NA
WP_094465213.1\|1944962_1945544_-\|tail	tail fiber assembly protein	K7PMC4	Enterobacterial_phage	7.9e-48	50.0
WP_094465215.1\|1945543_1946029_-	hypothetical protein	Q9MCR6	Enterobacteria_phage	8.6e-24	45.0
WP_094465217.1\|1946138_1946690_+	recombinase family protein	A0A1B0VBM1	Salmonella_phage	4.8e-79	82.5
WP_094465220.1\|1947035_1947356_+	hypothetical protein	K7PGV5	Enterobacterial_phage	5.5e-27	54.7
WP_042319958.1\|1947917_1948115_+	hypothetical protein	Q687E8	Enterobacteria_phage	9.5e-14	55.7
WP_084196591.1\|1948156_1950670_-	autotransporter outer membrane beta-barrel domain-containing protein	A0A2L1IV18	Escherichia_phage	3.3e-98	49.9
WP_042319956.1\|1951095_1951839_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	3.6e-21	34.5
WP_042319955.1\|1952009_1952390_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_042319952.1\|1952897_1955324_+	autotransporter outer membrane beta-barrel domain-containing protein	NA	NA	NA	NA
WP_042319950.1\|1955768_1956266_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_042319948.1\|1956301_1957852_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_042319946.1\|1957869_1959210_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_042319943.1\|1959206_1959896_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_042319942.1\|1959892_1961602_+	OmpA family protein	NA	NA	NA	NA
WP_042319939.1\|1961603_1962095_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_042319937.1\|1962265_1964917_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	3.2e-96	33.2
WP_084196582.1\|1964916_1967286_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.1e-18	30.4
WP_072015701.1\|1967298_1968132_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_094465224.1\|1968148_1970725_+	hypothetical protein	NA	NA	NA	NA
WP_139155855.1\|1970904_1971099_-	hypothetical protein	NA	NA	NA	NA
WP_139155856.1\|1971151_1971796_+	hypothetical protein	NA	NA	NA	NA
WP_139155857.1\|1971914_1972511_+	hypothetical protein	NA	NA	NA	NA
WP_042319930.1\|1972527_1972920_+	hypothetical protein	NA	NA	NA	NA
WP_042319928.1\|1973289_1975383_+	hypothetical protein	NA	NA	NA	NA
WP_042319927.1\|1975385_1976042_+	hypothetical protein	NA	NA	NA	NA
WP_072015700.1\|1976081_1976348_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_094465228.1\|1976347_1977583_+	hypothetical protein	NA	NA	NA	NA
WP_042319924.1\|1977829_1981123_+	type VI secretion protein VasK	NA	NA	NA	NA
WP_094465230.1\|1981119_1982715_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_094465232.1\|1982741_1984496_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_042319918.1\|1984459_1985545_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_042319914.1\|1985522_1986059_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_042319911.1\|1986058_1986514_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_5

2148357 : 2286311

155

Enterobacteria_phage(23.4%)

integrase,head,terminase,transposase,tail,tRNA,portal,plate,capsid

attL 2145372:2145388|attR 2243282:2243298

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2145372:2145388	attL	NA	NA	NA	NA
WP_001281697.1\|2148357_2148747_-	DNA-binding protein	Q6QIE8	Burkholderia_phage	3.8e-30	53.4
WP_000988476.1\|2148743_2149172_-	regulatory protein GemA	A4JWM5	Burkholderia_virus	1.1e-25	48.1
WP_000967768.1\|2149161_2149377_-	hypothetical protein	NA	NA	NA	NA
WP_001135926.1\|2149373_2150063_-	DUF2786 domain-containing protein	A0A1W6DYA0	Aeromonas_phage	5.9e-26	33.9
WP_001569383.1\|2150049_2150346_-	hypothetical protein	NA	NA	NA	NA
WP_016246284.1\|2150361_2150634_-	hypothetical protein	NA	NA	NA	NA
WP_001569384.1\|2150630_2150819_-	hypothetical protein	NA	NA	NA	NA
WP_000005725.1\|2150897_2151509_-	DUF3164 family protein	A0A2D1GNM4	Pseudomonas_phage	7.2e-76	68.5
WP_000835317.1\|2151526_2151796_-	hypothetical protein	NA	NA	NA	NA
WP_011410679.1\|2151798_2152965_-	AAA family ATPase	A4JWN1	Burkholderia_virus	1.3e-121	61.1
WP_011410680.1\|2152975_2154745_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q6QIE0	Burkholderia_phage	6.2e-229	67.8
WP_006687266.1\|2154748_2155657_-	DUF3102 domain-containing protein	A4JWN3	Burkholderia_virus	6.3e-76	55.4
WP_000042842.1\|2155666_2155972_-	helix-turn-helix domain-containing protein	Q5ZR02	Pseudomonas_phage	9.2e-24	58.0
WP_001041677.1\|2155968_2156193_-	hypothetical protein	NA	NA	NA	NA
WP_001569385.1\|2156281_2156692_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001569386.1\|2156727_2157261_+	hypothetical protein	NA	NA	NA	NA
WP_000664222.1\|2157308_2158079_-	DNA adenine methylase	A2I2Y7	Vibrio_virus	7.6e-99	64.9
WP_000793140.1\|2158326_2158677_+	membrane protein	A4JWP3	Burkholderia_virus	4.0e-23	54.8
WP_001569387.1\|2158676_2159414_+	transglycosylase SLT domain-containing protein	Q5ZQZ1	Pseudomonas_phage	1.9e-62	58.8
WP_011410681.1\|2159403_2160057_+	hypothetical protein	A0A0S4L1H0	Pseudomonas_phage	2.4e-08	30.7
WP_000175096.1\|2160053_2160386_+	hypothetical protein	Q6QIC4	Burkholderia_phage	1.1e-17	47.7
WP_006122433.1\|2160378_2160690_+	hypothetical protein	A0A0S4L0A3	Pseudomonas_phage	3.2e-32	63.6
WP_011410682.1\|2160689_2161235_+	DUF3486 family protein	A4JWJ3	Burkholderia_virus	1.2e-58	67.6
WP_016246282.1\|2161231_2162755_+	hypothetical protein	A4JWJ4	Burkholderia_virus	3.4e-183	62.4
WP_011410684.1\|2162754_2164251_+	DUF935 domain-containing protein	Q6QIC0	Burkholderia_phage	1.5e-170	59.8
WP_011410685.1\|2164231_2165053_+\|capsid	minor capsid protein	Q6QIB9	Burkholderia_phage	5.8e-97	61.5
WP_011410686.1\|2165055_2165514_+	phage virion morphogenesis protein	Q6QIB8	Burkholderia_phage	1.3e-29	43.6
WP_011410687.1\|2165728_2166826_+	hypothetical protein	A4JWJ9	Burkholderia_virus	5.0e-96	49.6
WP_011410688.1\|2166839_2167793_+	hypothetical protein	A4JWK0	Burkholderia_virus	7.5e-64	44.0
WP_011410689.1\|2167803_2168160_+	DUF2190 family protein	NA	NA	NA	NA
WP_000271666.1\|2168161_2168608_+	DUF1320 domain-containing protein	A4JWK2	Burkholderia_virus	1.1e-33	51.7
WP_001101809.1\|2168607_2169072_+	hypothetical protein	Q6QIB2	Burkholderia_phage	4.1e-39	51.7
WP_001446463.1\|2169068_2169323_+	hypothetical protein	NA	NA	NA	NA
WP_000729861.1\|2169312_2170740_+\|tail	tail protein	A4JWK5	Burkholderia_virus	3.4e-217	78.6
WP_162837902.1\|2170736_2171261_+\|tail	phage major tail tube protein	A4JWK6	Burkholderia_virus	4.7e-68	67.8
WP_000215406.1\|2171263_2171545_+	hypothetical protein	NA	NA	NA	NA
WP_011410690.1\|2171643_2171958_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_001148841.1\|2171923_2172061_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_011410691.1\|2172153_2174619_+\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	7.4e-172	42.8
WP_000458380.1\|2174618_2175503_+\|tail	phage tail protein	A4JWL1	Burkholderia_virus	3.1e-51	47.9
WP_011410692.1\|2175499_2175715_+	membrane protein	Q6QIA3	Burkholderia_phage	1.6e-17	57.1
WP_000808003.1\|2175702_2176872_+	phage late control D family protein	Q6QIA2	Burkholderia_phage	3.0e-86	49.1
WP_000929399.1\|2176871_2177384_+\|plate	phage baseplate assembly protein V	A4JWL4	Burkholderia_virus	9.4e-21	38.5
WP_000859115.1\|2177438_2177786_+\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	7.8e-35	63.3
WP_001569394.1\|2177776_2178880_+\|plate	baseplate J/gp47 family protein	A4JWL6	Burkholderia_virus	9.2e-106	53.5
WP_016246279.1\|2178872_2179451_+\|tail	phage tail protein I	A4JWL7	Burkholderia_virus	7.5e-67	66.3
WP_094465264.1\|2180324_2180510_+	hypothetical protein	NA	NA	NA	NA
WP_094465266.1\|2180490_2181072_-\|tail	tail fiber assembly protein	A0A0M4QWM3	Salmonella_phage	7.9e-32	41.3
WP_094465268.1\|2181071_2181608_-\|tail	tail fiber protein	K7PH60	Enterobacterial_phage	3.1e-30	48.0
WP_001569399.1\|2181656_2182238_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	2.9e-66	71.5
WP_042319594.1\|2184541_2185177_-	TetR family copper-responsive transcriptional repressor ComR	NA	NA	NA	NA
WP_042320085.1\|2185420_2185678_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_042320081.1\|2185774_2186740_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_042319593.1\|2186887_2190334_-	transcription-repair coupling factor	NA	NA	NA	NA
WP_094465270.1\|2190464_2191517_-	acyltransferase family protein	NA	NA	NA	NA
WP_042319589.1\|2191768_2192968_+	lipoprotein-releasing ABC transporter permease subunit LolC	NA	NA	NA	NA
WP_042319588.1\|2192960_2193662_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	1.9e-35	39.2
WP_042319586.1\|2193661_2194906_+	lipoprotein-releasing ABC transporter permease subunit LolE	NA	NA	NA	NA
WP_042319585.1\|2194995_2195907_+	N-acetylglucosamine kinase	NA	NA	NA	NA
WP_094465272.1\|2195922_2196744_+	NAD-dependent protein deacylase	A0A2I7S9Y2	Vibrio_phage	6.2e-22	34.6
WP_042319581.1\|2196779_2197826_-	spermidine/putrescine ABC transporter substrate-binding protein PotD	NA	NA	NA	NA
WP_042319578.1\|2197822_2198614_-	spermidine/putrescine ABC transporter permease PotC	NA	NA	NA	NA
WP_042319576.1\|2198610_2199468_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	1.5e-10	26.2
WP_042319574.1\|2199451_2200588_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	3.2e-29	40.3
WP_094465274.1\|2200838_2202065_+	peptidase T	NA	NA	NA	NA
WP_042319570.1\|2202168_2203290_-	[50S ribosomal protein L16]-arginine 3-hydroxylase	NA	NA	NA	NA
WP_042319568.1\|2203386_2204850_-	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_042320079.1\|2204849_2205521_-	two-component system response regulator PhoP	NA	NA	NA	NA
WP_042319567.1\|2205682_2207050_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	5.0e-109	45.5
WP_042320078.1\|2207053_2207695_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_042319566.1\|2207731_2208838_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_042319564.1\|2208891_2209353_-	NUDIX hydrolase	NA	NA	NA	NA
WP_042319561.1\|2209356_2210025_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_094465276.1\|2210196_2211447_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	6.7e-20	92.6
WP_094465278.1\|2211560_2212703_-\|integrase	tyrosine-type recombinase/integrase	O21929	Phage_21	8.2e-174	80.3
WP_094465280.1\|2212692_2212929_-	excisionase	NA	NA	NA	NA
WP_094465282.1\|2213033_2213327_-	hypothetical protein	A0A076GCP4	Escherichia_phage	2.5e-18	52.7
WP_094465284.1\|2213609_2213831_-	hypothetical protein	K7PLX1	Enterobacteria_phage	3.7e-14	64.5
WP_094465286.1\|2215254_2215911_-	helix-turn-helix domain-containing protein	K7PLZ5	Enterobacterial_phage	8.2e-86	67.0
WP_057101686.1\|2216010_2216208_+	hypothetical protein	K7PHB1	Enterobacterial_phage	9.8e-19	73.8
WP_094465288.1\|2216236_2216791_+	hypothetical protein	Q8SBF4	Shigella_phage	2.0e-48	52.8
WP_044256264.1\|2216954_2217134_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	4.1e-16	70.9
WP_094465290.1\|2217123_2218008_+	GntR family transcriptional regulator	A0A1C9IHW0	Salmonella_phage	8.0e-60	85.5
WP_094465292.1\|2218007_2218886_+	phage N-6-adenine-methyltransferase	Q8HA94	Salmonella_phage	2.0e-148	85.7
WP_094465294.1\|2218878_2220744_+	DNA cytosine methyltransferase	H9C171	Pectobacterium_phage	3.3e-212	57.9
WP_167382407.1\|2220743_2221061_+	LexA family transcriptional regulator	S5FXP5	Shigella_phage	3.8e-20	48.6
WP_044256254.1\|2221057_2221444_+	RusA family crossover junction endodeoxyribonuclease	K7PKN5	Enterobacterial_phage	4.0e-56	84.0
WP_094465858.1\|2221547_2222417_+	ORF6N domain-containing protein	F1C5A3	Cronobacter_phage	1.4e-61	46.1
WP_094465296.1\|2222413_2222935_+	hypothetical protein	V5URU3	Shigella_phage	1.7e-17	31.0
WP_094465298.1\|2222945_2223935_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.2e-150	73.9
WP_094465300.1\|2223949_2224549_+	hypothetical protein	H9C175	Pectobacterium_phage	8.3e-77	67.3
WP_094465304.1\|2224957_2226010_+	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	7.6e-174	82.1
WP_094465306.1\|2226147_2226462_+	hypothetical protein	H6WRZ3	Salmonella_phage	8.6e-49	94.2
WP_094465308.1\|2226463_2226994_+	lysozyme	H6WRZ4	Salmonella_phage	8.4e-89	88.2
WP_094465860.1\|2227017_2227536_+	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	1.1e-08	40.6
WP_167382387.1\|2228242_2232181_+	autotransporter outer membrane beta-barrel domain-containing protein	A0A2L1IV18	Escherichia_phage	2.3e-143	39.3
WP_167382388.1\|2232170_2232461_+	hypothetical protein	NA	NA	NA	NA
WP_167382389.1\|2232756_2233269_+\|terminase	terminase	K7PJS9	Enterobacteria_phage	2.7e-15	48.4
WP_094465314.1\|2233240_2235163_+\|terminase	phage terminase large subunit family protein	E4WL19	Enterobacteria_phage	0.0e+00	92.0
WP_043001120.1\|2235162_2235369_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	1.5e-25	86.8
WP_094465316.1\|2235365_2236958_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	1.5e-274	86.6
WP_044257427.1\|2236938_2238264_+	S49 family peptidase	O64320	Escherichia_phage	3.2e-185	78.5
WP_094465318.1\|2238273_2238603_+\|head	head decoration protein	E4WL24	Enterobacteria_phage	9.3e-38	72.6
WP_094465864.1\|2239081_2240317_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.4e-99	45.2
WP_094465320.1\|2240318_2240552_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_094465322.1\|2240562_2241384_+	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_072057059.1\|2241409_2241601_-	toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_094465324.1\|2241737_2242025_+	host cell division inhibitor Icd-like protein	A0A2H4JGW3	uncultured_Caudovirales_phage	4.9e-19	53.7
WP_094465326.1\|2242017_2242206_+	hypothetical protein	NA	NA	NA	NA
WP_054177289.1\|2242198_2242510_+	hypothetical protein	NA	NA	NA	NA
WP_094465328.1\|2242870_2244244_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.4e-172	67.0
2243282:2243298	attR	NA	NA	NA	NA
WP_094465330.1\|2244467_2245043_+	DUF4145 domain-containing protein	A0A222YYQ2	Escherichia_phage	1.3e-47	51.4
WP_094465332.1\|2245709_2246750_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	8.2e-64	41.4
WP_094465334.1\|2246759_2247101_+\|head	head decoration protein	NA	NA	NA	NA
WP_094465866.1\|2247105_2247489_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_094465336.1\|2247704_2248214_+\|terminase	terminase	O64316	Escherichia_phage	3.9e-35	45.4
WP_094465868.1\|2248240_2248831_+\|tail	tail assembly protein	K7PM97	Enterobacterial_phage	2.0e-62	66.3
WP_094465337.1\|2248827_2249214_+	hypothetical protein	NA	NA	NA	NA
WP_094465339.1\|2249344_2250217_-	hypothetical protein	NA	NA	NA	NA
WP_094465341.1\|2251235_2251634_+	hypothetical protein	K7P7M3	Enterobacteria_phage	1.1e-16	46.7
WP_094465343.1\|2251645_2251999_+\|tail	phage tail protein	K7PHD8	Enterobacteria_phage	3.0e-42	67.5
WP_094465345.1\|2252008_2252563_+\|tail	phage tail protein	K7P7A8	Enterobacteria_phage	5.9e-69	85.9
WP_094465347.1\|2252559_2252958_+\|tail	phage tail protein	K7P7G5	Enterobacteria_phage	1.4e-51	72.7
WP_094465349.1\|2252965_2253703_+\|tail	phage tail protein	M9NYX0	Enterobacteria_phage	6.0e-109	80.4
WP_094465351.1\|2253737_2254151_+\|tail	phage minor tail protein G	K7PM17	Enterobacteria_phage	1.6e-26	49.3
WP_046401854.1\|2254159_2254492_+\|tail	phage tail assembly protein T	K7P6V0	Enterobacteria_phage	1.3e-42	76.4
WP_094465353.1\|2254457_2256971_+\|tail	phage tail tape measure protein	K7PKR0	Enterobacteria_phage	0.0e+00	75.9
WP_094465355.1\|2256976_2257324_+\|tail	phage tail protein	K7PJT2	Enterobacteria_phage	4.9e-45	75.7
WP_094465357.1\|2257320_2258076_+\|tail	phage minor tail protein L	K7PGX3	Enterobacteria_phage	6.9e-129	84.9
WP_094465359.1\|2258077_2258788_+	peptidase P60	K7PGR2	Enterobacteria_phage	4.5e-138	93.2
WP_094465361.1\|2258818_2259154_+	hypothetical protein	Q6UAW3	Klebsiella_phage	3.0e-23	47.7
WP_094465870.1\|2259229_2259823_+\|tail	tail assembly protein	K7PM97	Enterobacterial_phage	8.5e-66	66.5
WP_094465363.1\|2259875_2263079_+	host specificity protein J	O64335	Escherichia_phage	0.0e+00	83.4
WP_094465365.1\|2263086_2264049_+	hypothetical protein	H6WRW5	Salmonella_phage	2.3e-116	63.8
WP_094465367.1\|2266708_2267527_-	DUF3037 domain-containing protein	NA	NA	NA	NA
WP_094465369.1\|2267523_2268264_-	hypothetical protein	NA	NA	NA	NA
WP_094465371.1\|2268365_2268605_-	DinI family protein	K7P6H1	Enterobacteria_phage	1.2e-31	87.3
WP_094465375.1\|2269361_2270408_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_004892953.1\|2270902_2271055_+	isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-18	92.0
WP_042320076.1\|2271293_2271476_-	hypothetical protein	NA	NA	NA	NA
WP_042319557.1\|2271688_2272180_-	response regulator transcription factor	NA	NA	NA	NA
WP_042319554.1\|2272349_2273654_-	hypothetical protein	NA	NA	NA	NA
WP_094465377.1\|2273650_2274370_-	molecular chaperone	NA	NA	NA	NA
WP_052425384.1\|2274409_2276995_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_167382390.1\|2277115_2277697_-	fimbrial protein	NA	NA	NA	NA
WP_042319548.1\|2278522_2279125_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_042319545.1\|2279168_2279864_+	B3/4 domain-containing protein	NA	NA	NA	NA
WP_042319541.1\|2280301_2281033_-	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	2.9e-55	50.8
WP_042319539.1\|2281256_2282477_-	diguanylate phosphodiesterase	NA	NA	NA	NA
WP_042319536.1\|2282801_2283041_+	hypothetical protein	NA	NA	NA	NA
WP_052425383.1\|2283112_2283418_+	hypothetical protein	NA	NA	NA	NA
WP_167382408.1\|2283448_2283727_+	two-component-system connector protein AriR	NA	NA	NA	NA
WP_042319534.1\|2283840_2284401_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_084196574.1\|2284784_2284901_-	arsenate reductase	NA	NA	NA	NA
WP_042320067.1\|2284868_2286311_+\|transposase	IS1182 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2924331 : 3001551

Vibrio_phage(56.1%)

integrase,head,tail,transposase,tRNA,plate

attL 2957023:2957039|attR 2981245:2981261

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042318579.1\|2924331_2924916_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_042318577.1\|2925032_2926124_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_052425369.1\|2926223_2927909_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.2e-11	37.2
WP_139155865.1\|2928574_2928829_-	hypothetical protein	NA	NA	NA	NA
WP_042318574.1\|2928922_2929402_+	transcriptional regulator	NA	NA	NA	NA
WP_042318573.1\|2929461_2932617_-	multidrug efflux RND transporter permease subunit OqxB	NA	NA	NA	NA
WP_042318571.1\|2932640_2933816_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_042318569.1\|2934150_2934489_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_052425368.1\|2934681_2935500_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_042318568.1\|2935752_2936463_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_042318566.1\|2936672_2936897_-	hypothetical protein	NA	NA	NA	NA
WP_042318563.1\|2937107_2938577_+	hypothetical protein	NA	NA	NA	NA
WP_042318562.1\|2938626_2940528_-	PTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR	NA	NA	NA	NA
WP_042318561.1\|2940771_2941842_+	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_042318559.1\|2941852_2942485_+	dihydroxyacetone kinase ADP-binding subunit DhaL	NA	NA	NA	NA
WP_042318557.1\|2942495_2943929_+	dihydroxyacetone kinase subunit DhaM	NA	NA	NA	NA
WP_042318556.1\|2944031_2945738_+	alpha,alpha-trehalase	NA	NA	NA	NA
WP_042318694.1\|2945791_2947903_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_042318555.1\|2948021_2948276_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_042318554.1\|2948479_2949214_+	flagellar brake protein	NA	NA	NA	NA
WP_042318553.1\|2949214_2949826_-	membrane-bound lytic murein transglycosylase EmtA	NA	NA	NA	NA
WP_042318552.1\|2949964_2950879_+	muramoyltetrapeptide carboxypeptidase	NA	NA	NA	NA
WP_042318551.1\|2950976_2952713_+	potassium/proton antiporter	NA	NA	NA	NA
WP_094465477.1\|2952821_2953892_-	catabolic alanine racemase DadX	NA	NA	NA	NA
WP_042318547.1\|2953904_2955203_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_042318545.1\|2955531_2957064_+	SpoVR family protein	NA	NA	NA	NA
2957023:2957039	attL	NA	NA	NA	NA
WP_042318544.1\|2957097_2957817_-	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_042318543.1\|2958039_2959584_+	Na(+)/H(+) antiporter NhaB	NA	NA	NA	NA
WP_042318542.1\|2959725_2960256_+	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_080343242.1\|2960304_2960766_-	YcgN family cysteine cluster protein	NA	NA	NA	NA
WP_042318541.1\|2960843_2961503_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_042318540.1\|2961571_2961865_-	hypothetical protein	NA	NA	NA	NA
WP_042318538.1\|2961991_2962699_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_042318537.1\|2962722_2963535_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_001185666.1\|2963538_2963805_+	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_167382392.1\|2964798_2965467_-	metal-binding protein ZinT	NA	NA	NA	NA
WP_042318536.1\|2965614_2966043_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	8.7e-28	48.6
WP_042318535.1\|2966076_2966937_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_042318533.1\|2967118_2968003_+	SED family class A beta-lactamase	A0A1B0VBP7	Salmonella_phage	3.7e-105	72.9
WP_094465479.1\|2968462_2969017_-	recombinase family protein	A0A1S6L009	Salmonella_phage	4.4e-80	83.5
WP_094465481.1\|2969446_2969689_+	hypothetical protein	NA	NA	NA	NA
WP_094465483.1\|2969666_2970092_-\|tail	tail fiber assembly protein	S5FXM8	Shigella_phage	3.2e-22	45.2
WP_094465485.1\|2970450_2970879_+	hypothetical protein	NA	NA	NA	NA
WP_094465487.1\|2970890_2971316_+\|tail	tail assembly chaperone	S5FXM8	Shigella_phage	6.4e-15	37.0
WP_046493927.1\|2971287_2971881_-\|tail	phage tail protein	K7PMC4	Enterobacterial_phage	1.0e-55	56.1
WP_094465489.1\|2971880_2972699_-\|integrase	integrase	K7PH60	Enterobacterial_phage	2.5e-31	47.1
WP_058587150.1\|2972698_2973289_-	DUF2313 domain-containing protein	M4M9M8	Vibrio_phage	5.4e-52	49.7
WP_094465491.1\|2973273_2974350_-\|plate	baseplate J/gp47 family protein	A0A2I7S9E5	Vibrio_phage	2.1e-99	52.7
WP_058587152.1\|2974339_2974792_-	phage GP46 family protein	M1PPW1	Vibrio_phage	6.8e-23	46.9
WP_094465493.1\|2974788_2975331_-\|plate	phage baseplate assembly protein	M1Q572	Vibrio_phage	4.2e-27	39.9
WP_094465494.1\|2975321_2976413_-\|tail	phage tail protein	M1PVV2	Vibrio_phage	1.7e-88	46.5
WP_094465496.1\|2976412_2977744_-	DNA circularization N-terminal domain-containing protein	A0A2I7S9E8	Vibrio_phage	8.3e-77	37.2
WP_094465498.1\|2977743_2979660_-\|tail	phage tail protein	M4MHE6	Vibrio_phage	1.1e-61	35.0
WP_058587157.1\|2979746_2980142_-	hypothetical protein	M1NVT1	Vibrio_phage	3.1e-19	42.9
WP_058587158.1\|2980145_2980502_-\|tail	phage tail protein	A0A2I7S9D5	Vibrio_phage	5.9e-22	43.8
WP_058587159.1\|2980511_2981990_-\|tail	phage tail protein	M1Q565	Vibrio_phage	2.3e-152	54.6
2981245:2981261	attR	NA	NA	NA	NA
WP_058587160.1\|2981989_2982178_-	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_094465500.1\|2982170_2982782_-	hypothetical protein	M4MHF0	Vibrio_phage	1.6e-35	43.9
WP_094465502.1\|2982778_2983321_-	phage morphogenesis protein	A0A2I7S9D7	Vibrio_phage	8.1e-55	59.8
WP_094465504.1\|2983320_2983761_-	DUF1320 domain-containing protein	A0A2I7S9E9	Vibrio_phage	1.7e-34	49.3
WP_094465506.1\|2983760_2984363_-	hypothetical protein	NA	NA	NA	NA
WP_094465508.1\|2984446_2985340_-\|head	phage head protein	M4MB71	Vibrio_phage	3.8e-94	55.7
WP_058587166.1\|2985343_2986300_-	peptidase	M1Q578	Vibrio_phage	8.9e-81	50.8
WP_058587167.1\|2986503_2987298_-	hypothetical protein	M4M9M5	Vibrio_phage	1.3e-90	57.9
WP_058587168.1\|2987290_2988859_-	DUF935 domain-containing protein	A0A2I7S9K0	Vibrio_phage	9.6e-157	54.8
WP_094465510.1\|2988858_2990442_-	hypothetical protein	M4MHG0	Vibrio_phage	3.5e-199	68.9
WP_058587170.1\|2990438_2991017_-	DUF3486 family protein	M4MCR3	Vibrio_phage	3.5e-40	50.8
WP_094465512.1\|2991006_2991279_-	hypothetical protein	NA	NA	NA	NA
WP_094465514.1\|2991268_2991646_-	hypothetical protein	NA	NA	NA	NA
WP_058587173.1\|2991648_2991936_-	hypothetical protein	M1PPT9	Vibrio_phage	1.1e-26	64.5
WP_058587174.1\|2991947_2992253_-	DUF2730 family protein	M1Q558	Vibrio_phage	1.3e-12	36.2
WP_058587175.1\|2992253_2992460_-	conjugal transfer protein TraR	NA	NA	NA	NA
WP_094465516.1\|2992456_2993065_-	hypothetical protein	NA	NA	NA	NA
WP_094465518.1\|2993052_2993460_-	hypothetical protein	NA	NA	NA	NA
WP_058587178.1\|2993452_2993671_-	hypothetical protein	A0A0C4UQR6	Shigella_phage	3.2e-26	72.2
WP_094465520.1\|2993672_2994263_-	N-acetylmuramidase	A0A2I7S9B9	Vibrio_phage	4.1e-36	45.7
WP_094465522.1\|2994348_2994867_-	hypothetical protein	NA	NA	NA	NA
WP_094465524.1\|2994879_2995287_-	transcriptional regulator	A0A0C4UR27	Shigella_phage	2.3e-38	63.5
WP_094465526.1\|2995283_2995811_-	regulatory protein GemA	A0A0C4UQU3	Shigella_phage	1.7e-41	48.1
WP_139155866.1\|2995807_2996023_-	hypothetical protein	NA	NA	NA	NA
WP_094465530.1\|2996029_2996464_-	hypothetical protein	R9TQX3	Aeromonas_phage	8.6e-15	86.0
WP_058587185.1\|2996553_2997081_-	host-nuclease inhibitor protein Gam	C9DGL8	Escherichia_phage	3.7e-44	56.7
WP_094465532.1\|2997094_2997349_-	host nuclease inhibitor protein	A0A0U5KSG7	unidentified_phage	3.5e-16	48.1
WP_058587187.1\|2997366_2997606_-	hypothetical protein	A0A0C4UQY4	Shigella_phage	2.8e-15	55.4
WP_094465534.1\|2997610_2998549_-	AAA family ATPase	A0A0C4UQR3	Shigella_phage	1.3e-76	49.3
WP_094465536.1\|2998627_3000610_-\|transposase	transposase	A0A0C4UR24	Shigella_phage	1.3e-190	51.8
WP_058587190.1\|3000609_3000846_-	helix-turn-helix domain-containing protein	A0A2I7S995	Vibrio_phage	8.7e-14	54.5
WP_094465538.1\|3001029_3001551_+	helix-turn-helix transcriptional regulator	A0A076FRF7	Pseudomonas_phage	6.5e-09	50.0

DBSCAN-SWA_7

3346652 : 3355073

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094465584.1\|3346652_3348686_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	8.0e-55	27.6
WP_042318022.1\|3348887_3349346_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	3.9e-50	66.7
WP_042318021.1\|3349391_3349862_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.6e-62	76.8
WP_042318020.1\|3349908_3350628_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_042318019.1\|3350620_3352309_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	1.3e-279	91.7
WP_042318017.1\|3352531_3353263_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	5.2e-105	92.5
WP_042318015.1\|3353322_3353430_+	protein YohO	NA	NA	NA	NA
WP_042318013.1\|3353410_3354142_-	ABC transporter permease	NA	NA	NA	NA
WP_042318011.1\|3354125_3355073_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	9.0e-09	26.5

DBSCAN-SWA_8

3824087 : 3869796

Escherichia_phage(66.67%)

tRNA,transposase,integrase

attL 3861344:3861361|attR 3879924:3879941

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042325913.1\|3824087_3824855_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_042325915.1\|3824899_3825448_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_042325918.1\|3825466_3825715_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_042325920.1\|3825970_3827332_-	signal recognition particle protein	NA	NA	NA	NA
WP_042325922.1\|3827497_3828289_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_102601129.1\|3828308_3829595_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_042325925.1\|3829674_3830268_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_042325929.1\|3830390_3831269_+	NAD(+) kinase	NA	NA	NA	NA
WP_042325930.1\|3831354_3833016_+	DNA repair protein RecN	NA	NA	NA	NA
WP_042325933.1\|3833165_3833510_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_084196690.1\|3833566_3833857_-	RnfH family protein	NA	NA	NA	NA
WP_071887579.1\|3833846_3834323_-	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_042325938.1\|3834453_3834936_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.4e-29	48.1
WP_094465630.1\|3835552_3836755_+	BapA prefix-like domain-containing protein	NA	NA	NA	NA
WP_167382396.1\|3836751_3837495_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|3837506_3838211_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001044210.1\|3838216_3838357_+	hypothetical protein	NA	NA	NA	NA
WP_002075255.1\|3839003_3840017_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	6.1e-72	45.5
WP_012695484.1\|3840179_3840761_+	aminoglycoside N-acetyltransferase AAC(6')-IIc	NA	NA	NA	NA
WP_006473457.1\|3841248_3842604_+\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	2.2e-45	29.7
WP_012695485.1\|3842845_3843655_+	AAC(3)-II family aminoglycoside N-acetyltransferase	NA	NA	NA	NA
WP_012695486.1\|3843782_3844196_+	NAD(+)--rifampin ADP-ribosyltransferase	NA	NA	NA	NA
WP_167382377.1\|3844467_3844605_+	hypothetical protein	NA	NA	NA	NA
WP_012695487.1\|3844558_3844990_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_000679427.1\|3846299_3846647_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|3846640_3847480_+	sulfonamide-resistant dihydropteroate synthase Sul1	NA	NA	NA	NA
WP_000376623.1\|3847607_3848108_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001067855.1\|3848183_3848888_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_011977770.1\|3848833_3849265_-	hypothetical protein	A0A077SK32	Escherichia_phage	2.9e-55	97.3
WP_002903955.1\|3850521_3851424_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_002210513.1\|3851685_3852447_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002904004.1\|3852467_3853328_-	class A extended-spectrum beta-lactamase SHV-12	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_001067855.1\|3853464_3854169_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_094465632.1\|3854344_3863083_+	type I secretion C-terminal target domain-containing protein	NA	NA	NA	NA
3861344:3861361	attL	NA	NA	NA	NA
WP_094465634.1\|3863166_3864573_+	TolC family outer membrane protein	NA	NA	NA	NA
WP_042325942.1\|3864569_3866756_+	type I secretion system permease/ATPase	F2Y302	Organic_Lake_phycodnavirus	2.6e-19	35.1
WP_042325944.1\|3866736_3867927_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_094465636.1\|3868554_3869796_+\|integrase	integrase	A0A1B5FPC6	Escherichia_phage	7.0e-102	47.3
3879924:3879941	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022697

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP022698

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP022696

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP022695

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection