CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP022709	Lactobacillus sakei strain WiKim0063 chromosome, complete genome	1 crisprs	DinG,DEDDh,cas3,csa3	0	7
NZ_CP022710	Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence	1 crisprs	csa3	2	2
NZ_CP022711	Lactobacillus sakei strain WiKim0063 plasmid pLBS02, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022709_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022709_1

1713589-1714148

Orphan

Consensus_repeat	Method
TTAGATGTTTCAAATTGGGATAC	CRISPRCasFinder
ATTACCGAATTAGATGTTTCAAATTGGGATAC	PILER-CR

7 spacers

The CRISPR arrays of NZ_CP022709_1

>merge|NZ_CP022709|1|1713589-1714148|CRISPRCasFinder,PILER-CR
CTAAATAGTACGAATTGGGACACTTCTAATATTCAAAATATGAATAACACATTTTTCAATTGTACGGCCTTAACGAACTTAGATGTTTCAAAATGGCAGACGGCAAAAATGACTAATCTGGGGAGTACCTTTTCACAATCGGGCATTACTGTTTTAGATGTTTCAAATTGGGATACCAGTCACGTTACTAATTTAAGTAGTACTTTTCTGAATACTAGTATTGCCGAATTAGATGTTTCGAATTGGGATACAAGCCAAGTGACGACAATGGCTTATACTTTTTCGGGATGTTCAAGACTTGAAACCTTAGATGTCTCAAAATGGCAGCTCGGCAAAAATACATCGTTGTCTTACACGTTCAGCGGTGATCAAAGATTAACGCAGTTAGACGTTTCTAAGTGGCAAACCGCTAATGTGACGAATATGGCTTCAACATTTTCCGGGACTGTCGGTGTTAAGACTTTAGCGGTTAAAGATTGGCAGACCACTAAAGTGACAACCATGGCGGGCATGTTTGCCAAGAGTGGCGTTGATCAGTTAGAAATTGCTGATTGGGATAC

>NZ_CP022709|1|1|1713589-1714148|CRISPRCasFinder
CTAAATAGTACGAATTGGGACAC	TTCTAATATTCAAAATATGAATAACACATTTTTCAATTGTACGGCCTTAACGAAC
TTAGATGTTTCAAAATGGCAGAC	GGCAAAAATGACTAATCTGGGGAGTACCTTTTCACAATCGGGCATTACTGTT
TTAGATGTTTCAAATTGGGATAC	CAGTCACGTTACTAATTTAAGTAGTACTTTTCTGAATACTAGTATTGCCGAA
TTAGATGTTTCGAATTGGGATAC	AAGCCAAGTGACGACAATGGCTTATACTTTTTCGGGATGTTCAAGACTTGAAACC
TTAGATGTCTCAAAATGGCAGCT	CGGCAAAAATACATCGTTGTCTTACACGTTCAGCGGTGATCAAAGATTAACGCAG
TTAGACGTTTCTAAGTGGCAAAC	CGCTAATGTGACGAATATGGCTTCAACATTTTCCGGGACTGTCGGTGTTAAGACT
TTAGCGGTTAAAGATTGGCAGAC	CACTAAAGTGACAACCATGGCGGGCATGTTTGCCAAGAGTGGCGTTGATCAG
TTAGAAATTGCTGATTGGGATAC

>NZ_CP022709|1|1|1713667-1713839|PILER-CR
TTAGATGTTTCAAAATGGCAGACGGCAAAAAT	GACTAATCTGGGGAGTACCTTTTCACAATCGGGCATTACTGTTTTAGA
TGTTTCAAATTGGGATACCAGTCACGTTACTA	ATTTAAGTAGTACTTTTCTGAATACTAGTATTGCCGAATTAGA
TGTTTCGAATTGGGATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022709.1\|WP_035145621.1\|1703596_1704619_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP022709.1\|WP_025016102.1\|1716096_1717134_+\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP022709.1\|WP_025016105.1\|1711619_1712612_+\|choloylglycine-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238303
NZ_CP022709.1\|WP_011373914.1\|1704762_1705317_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP022709.1\|WP_025016101.1\|1718300_1718864_+\|DUF916-domain-containing-protein	unknown	unknown	gnl\|CDD\|368712
NZ_CP022709.1\|WP_025016099.1\|1719345_1719630_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP022709.1\|WP_025016096.1\|1722911_1723214_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|366278
NZ_CP022709.1\|WP_025016106.1\|1710805_1711423_-\|DUF1361-domain-containing-protein	unknown	unknown	gnl\|CDD\|369208
NZ_CP022709.1\|WP_025016098.1\|1719861_1721781_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375450
NZ_CP022709.1\|WP_052039193.1\|1717352_1718030_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022709.1\|WP_035145629.1\|1715150_1716023_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP022709.1\|WP_025016100.1\|1718918_1719353_+\|DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP022709.1\|WP_025016108.1\|1702623_1703532_+\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_CP022709.1\|WP_056936442.1\|1708053_1710177_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_CP022709.1\|WP_025016109.1\|1702208_1702604_+\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_CP022709.1\|WP_011373915.1\|1705313_1706873_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP022709.1\|WP_011373916.1\|1706968_1707658_+\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|172606
NZ_CP022709.1\|WP_094365873.1\|1721790_1722780_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375451
NZ_CP022709.1\|WP_016264496.1\|1710212_1710749_+\|DUF308-domain-containing-protein	unknown	unknown	gnl\|CDD\|225786
NZ_CP022709.1\|WP_157697960.1\|1718032_1718209_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694

Protein	Function_ID	Function_description	E-value
NZ_CP022709.1\|WP_035145621.1\|1703596_1704619_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.93039e-104
NZ_CP022709.1\|WP_025016102.1\|1716096_1717134_+\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	5.18202e-43
NZ_CP022709.1\|WP_025016105.1\|1711619_1712612_+\|choloylglycine-hydrolase-family-protein	gnl\|CDD\|238303	cd00542, Ntn_PVA, Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins. PVA has an N-terminal nucleophilic cysteine, as do other members of the Ntn hydrolase family to which PVA belongs. This nucleophilic cysteine is exposed by post-translational prossessing of the PVA precursor. PVA forms a homotetramer.	1.30921e-149
NZ_CP022709.1\|WP_011373914.1\|1704762_1705317_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.48625e-10
NZ_CP022709.1\|WP_025016101.1\|1718300_1718864_+\|DUF916-domain-containing-protein	gnl\|CDD\|368712	pfam06030, DUF916, Bacterial protein of unknown function (DUF916). This family consists of several hypothetical bacterial proteins of unknown function.	3.84271e-31
NZ_CP022709.1\|WP_025016099.1\|1719345_1719630_+\|hypothetical-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.51461e-06
NZ_CP022709.1\|WP_025016096.1\|1722911_1723214_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|366278	pfam00746, Gram_pos_anchor, LPXTG cell wall anchor motif.	6.9213e-05
NZ_CP022709.1\|WP_025016106.1\|1710805_1711423_-\|DUF1361-domain-containing-protein	gnl\|CDD\|369208	pfam07099, DUF1361, Protein of unknown function (DUF1361). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins.	1.89048e-27
NZ_CP022709.1\|WP_025016098.1\|1719861_1721781_+\|hypothetical-protein	gnl\|CDD\|375450	pfam17965, MucBP_2, Mucin binding domain. This domain is found in bacterial cell surface proteins that interact with mucins. The archetypal member of this family is the Mub-R5 B1 domain. This domain has a beta-grasp fold.	1.10213e-12
NZ_CP022709.1\|WP_035145629.1\|1715150_1716023_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.3377e-16
NZ_CP022709.1\|WP_025016100.1\|1718918_1719353_+\|DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	7.04333e-16
NZ_CP022709.1\|WP_025016108.1\|1702623_1703532_+\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	2.55136e-126
NZ_CP022709.1\|WP_056936442.1\|1708053_1710177_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP022709.1\|WP_025016109.1\|1702208_1702604_+\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	4.56237e-74
NZ_CP022709.1\|WP_011373915.1\|1705313_1706873_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.83511e-67
NZ_CP022709.1\|WP_011373916.1\|1706968_1707658_+\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|172606	PRK14116, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	1.12494e-164
NZ_CP022709.1\|WP_094365873.1\|1721790_1722780_+\|hypothetical-protein	gnl\|CDD\|375451	pfam17966, Mub_B2, Mub B2-like domain. This entry corresponds to the Mub B2 domain. This domain is related to the Mub B1 domain pfam17965. This domain may be involved in mucin binding. This domain is often found associated with the related pfam17965 in bacterial cell surface proteins.	5.60419e-17
NZ_CP022709.1\|WP_016264496.1\|1710212_1710749_+\|DUF308-domain-containing-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	4.18527e-14
NZ_CP022709.1\|WP_157697960.1\|1718032_1718209_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	0.00128998

>NZ_CP022709.1|WP_025016105.1|1711619_1712612_+|choloylglycine-hydrolase-family-protein
MCTSLTYSTVDGHHFLARTMDFSFELNGNPLFLPRQHQWQPVLEKQAIQNQYALMGAGAKLGDQYLVADGFNEHGLGCAELYFAHAAVYEPQPVPNKLNLVAEEFIVWVLGNYQTLEEVAADLDNVRIIESDQGVMGANQPLHWILSDRSGKTMVIEPRGNGLQLIDDPVGVMTNTPDLDWHIKNLSNYLNLQPQPFMERPFGNYQAGPFSQGTGTQALPGSYTPPDRFVRAAYSRQYMPEANNVAEGVNHILHILDNVTIPKGVNIGSGGSSDYTQYQGISGLNNLAYYMVNYDNRHVYQTNLTTDLIENQKEPVIYHLPQGQQNTILN
>NZ_CP022709.1|WP_025016106.1|1710805_1711423_-|DUF1361-domain-containing-protein
MSKKVLTIHAIILLFFALILLYQSRFAFLIWNIILALIPFDLSLLGRLFKNSRWRYLIGVVWLLFFPNALYMITDFSHLSSIGVGLSTAFQFVEYAILAGGIFVGVTLGLTSLFILYPLFIPNYQRLVNQAATFGVLSVCSSVAIYIGRFLRINSWDVFYQLHTTIASVLGVLNQSDFWIFVIAFSILQLILMLMGYQLAQLDDL
>NZ_CP022709.1|WP_016264496.1|1710212_1710749_+|DUF308-domain-containing-protein
MLSKNISNKLRQATGVNGLLSLILGLLILFLPGQSAMGVTVMVGVVFIIIGLFDILSIFKEVDENTWVRLGHLLLGLLYLIVGIFVCVNLAASATYLFLLVGIFVGITWLVEGFVELGTVRLAVSKGWTIFSAVLSIVAGIILLMTPLYGAVMLWTLLGAILVVLGIFKVAHYLAWQK
>NZ_CP022709.1|WP_056936442.1|1708053_1710177_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MANMYGNDPFFNNDMDDIFNQVFRRMGNSESARYVINGRELSPDEFAQYRATGKLPNREKEIEIKQNGEHALKKGGILEKLGRNLTQEARDGLLDPVIGRYNEIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQEIVAGKVPEAIKDKEIYSIDLSSLEAGTQYRGSFEENIKNLIKEVKAAGNVILFFDEIHQILGIGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEYRNTILKNAALARRFNDVLVNEPSAADTVKILQGIKGLYEKHHHIELPDDVLKAAVDYSAQYIPQRTLPDKAIDLLDMTAAHLAAKRPETDKAKLAAELKQLEADKAAAVEAENYQAAEELKVKIEKIKAQLATDDQHAAEVIATVDDIAQSVERLTGIPVAKMGSNDIQRLKNLGQRLKDKVIGQDEAVEMVARAIRRNRAGFSEGNQPIGSFLFVGPTGVGKTELAKQLALDMFGNKEAIIRLDMSEYADRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLFDEIEKADPQVLTLLLQVMDDGRLTDGQGNVIDFKNTVIIATSNAGFGNEKLTMNDQEDAKLLDKLAPYFRPEFLNRFNGIVEFTHLTKADLSQIVDLMLTNVEQTLAKKELTLVVSKEAKDWLMEEGYDEAMGARPLRRVIEQQIRDKVTDFYLDHADVKDLKADLVDDQIVIQAVDSEN
>NZ_CP022709.1|WP_011373916.1|1706968_1707658_+|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MAKLVFIRHGQSEWNLSNQFTGWVDVNLSEEGVRQAQNAGALLKKEGILFDQAYTSVLTRAIKTLHYALEGSDQLWIPETKSWRLNERHYGALQGQNKAEAAEKWGDEQVHIWRRSYDTLPPLLDASDEGSAANDRRYAHLDPKAIPGGENLKVTLERVIPFWEDEIAPKLIDGQNIIVAAHGNSLRALTKYIENISDEDIMDVEMATGEPVVYDLDENLNVVSKKKLN
>NZ_CP022709.1|WP_011373915.1|1705313_1706873_+|MFS-transporter
MKKTTNRWIALVAMSLGVFMGLLDVTVVNVALPSMAVDFKTTFSNLQWVLNAYTLMYAVSLLIVSKLGDMFGRKKIFIMSMILFTAASVVNGLAPNLLVLDIGRAIQAIGGSGMMSLSMALVASNFEGRERGTALGILGSVIGFSTAIGPLVGGFLVESFGWPSIFFVNLPVGIISVYLVIRNVKETPAYGAGESIDFMGMFLSAIGLFSGIYGLIQKEQHMHWAWTDMRIMGWLVASVLILALFVFVELKAKAPMMNLTLLTNRHFVGVVILAFSLGAGIFALAAYQTSLMQNYMGYSAFSTGVHQLPMSLWSLVLGPFTGVLGYKFGKKWLIAFGFTVSALGLLIFRQVTTTDFTYMQLLPLLALTGLGNAIINPMINTAAMDNINPQEIGMASGLLNVFRQIGITVGVVILGLSQTNAYESSLSTGFSGSSIPKAAATGIHQSLVEAGAFSGHAIAWGQQLVKTPYAAKVQQMVVTAFDKGMIAVVTTSLVLMVIAILAALFLLKETKSVDQKPQK
>NZ_CP022709.1|WP_011373914.1|1704762_1705317_+|PadR-family-transcriptional-regulator
MYELLMLSALMSRNMSGYKLRIILENAMLPRRKISNGVLYPLLDKLENKGCIGFDEADQDSRGTKIAHITEEGRRYFAELMTKPVAHDAKWDDAYRFKMRGMHYIDSEEQISILQDYRNELAEDLHVYLGIKNHLTDLRDEEGTNTNYYQWQVRSMDFVITTLKAKVDWLEAQIKEIEKMEIVK
>NZ_CP022709.1|WP_035145621.1|1703596_1704619_+|LacI-family-DNA-binding-transcriptional-regulator
MGEVNVVRKVTIKDVAALAQTSVTTVSLILNNKGQRFSAETIARVRAAREKISYEPDYFAQNMVNKETKTIAVLVPDINNPFFSQFIQGVEEVAYQYDFIPLIYSAGQNNQKVNYYLKELVRRNVDGFILAVSHIEEETLEGHLKQRKIPYILLDQSEKQHQSDEIAVADTEGGRMAANYLIEKGHRQIGIVLPEQRAWNIEQRFIGYQAALVSHQITVNPDWQITTPLSKQGGYQVAQQVIDSGVSAVFAVNDELAIGLARGLAELGHAVPESISIIGYDDIDWCEYVTPRLTTIKQPILALGQEATRLLLNRIEKPTLGMQQKMLSVELVERDSVQAQ
>NZ_CP022709.1|WP_025016108.1|1702623_1703532_+|ribokinase
MKKVIVLGSTNVDTILNVQRFPQPGETLAMDGRAVAGGGKGANQAIAAVRSGAQTAFISKVGKEGAADFMIDTFKKDGMNVDHVRCSETAGTGQAYIMVDAQGQNSILIYGGANQDVTVEDVHEAETAIKAADRIVAQFEVPIPAIIEAFKIARANGVQTILNPAPAIKNIPAELLAVTDMIVPNETEAEIITGIKVTDEASMQANAEAMFKLGIKVVIITVGSKGSFYATPTATGFVPAFKVNAVDTTAAGDTFIGALSTKLELDYSNIEAAMTYANKASSIAVQTKGAQNSIPYEKDIQL
>NZ_CP022709.1|WP_025016109.1|1702208_1702604_+|D-ribose-pyranase
MRKTKVINTQISSVISDMGHFDTLSIGDAGMPVPAGTKKIDVAIENGVPSFIQVLTNILSELEVQKVYLANEIKTANPEQLAAIKALIGETPIEFIDHSQMKQDLNKAKAFVRTGEMTPYSNIILESGVVF
>NZ_CP022709.1|WP_035145629.1|1715150_1716023_+|WxL-domain-containing-protein
MSQPVTSNTVDMNVVQSEHQLTIRYVDLDEDLSQPASAGTQIAAPITVSGKTGTALSTLLPGQQVAPKVIEGYTIYSVSEDPDLKPENWQKAYRDDPQIGDQDRIITYGYKKAMLSIDAPSSWEFGDYNNKPMDRTYYLNHNQGTPQAVTVTDNYGVQNWQLQVSQAKPFVDSEQHELTDAKWAFSNGNVKTLSNTDVGTVTNNSEHFTLASGQSATLMTMTKSGHFQSDSPDTSDPENPYTQVGQGQWAYRFGDEKSADYSIGLNVPATTKRYTGHYRTKLTWSLSVGP
>NZ_CP022709.1|WP_025016102.1|1716096_1717134_+|DUF916-and-DUF3324-domain-containing-protein
MRLRKWTTGLAVGLFGWLLLASNQPVSAAQEHIDFEVEKVKSNRQVDQENRFFDLGIEPGKKETIQVLVHNFSDKNIKVHSEIDNSLTQQGGGIIYRPTKDGIIKETSHTLMDVAKVHRADRVITLGPNEVKKVSATITMPSEQTKGMIYGAWHFIEYGQKETDNHSNVSGSYAYNMGIVLRGKPYEIYPELKYQGVNPTVRNGHPALGIQLNNTKPMAIKNAKVKAVVYKNGFFKDKRVYETDSVDVAPNSQWTVPISWAFDRLKPGRYNISISVKGNSYWNQLPMSWHFRKKITINQQQADKINQASVKKPVNKWAYVATASGILMLVSFWFVYRVLKLTRGL
>NZ_CP022709.1|WP_052039193.1|1717352_1718030_+|hypothetical-protein
MKFTKLTSTVLTASTLLAILAPATIASAATPKDDAAANGGTKLPMTDTTDAGISFGDTHDNGNSGYLRLQMVPKTLDFGNHAKYDAAHTNFDATGANLGVVGNDTHASYDQQDSNKTEILTTSDANLKAVQGTAWATVVDKQVENPELAAATPKANTAGDWKLTVSADGDGLKAGGHTIADANLVFGNTKYGRTADIYGLTNQDQDNDGYTALGQQMQHTQNQLA
>NZ_CP022709.1|WP_157697960.1|1718032_1718209_+|WxL-domain-containing-protein
MSTPNEEKVVGTAAKDAGDGANVFGWNPSDIRLALNGSNDVATGEYHAGLTWTLNTTI
>NZ_CP022709.1|WP_025016101.1|1718300_1718864_+|DUF916-domain-containing-protein
MFKRLNMLWFCLILVDLLTVQTSNPVFAKSEGLAIPAEPKATFMLRPELPKDNLGCKRLGYFNLKLKRGQQRTVFLKVFNPTAQPLTIYGRVKDATTNDNATVDYLGANPIDRQLLKQPGSQLVKVPRATKLQPNETKRLKVTIQAPAKGFKGQKATAINLSTNQLAKHNAVENHYVYAITLILNGR
>NZ_CP022709.1|WP_025016100.1|1718918_1719353_+|DUF3324-domain-containing-protein
MKQKRAAISVAIANPNPAYLKSATVKVDLQNQQWSLIRYQDQKSNRKIAPNSRFYEDVPLGGKRLVAGVYRMTLTIKTAHQQQIIHKNIAISKGQARYINQNNDQYLKYRNLLLLGGFVMVLMGVIGGYRILKVKHMKRDEHDD
>NZ_CP022709.1|WP_025016099.1|1719345_1719630_+|hypothetical-protein
MIKSEKNQYLEGYQLLTRLENGLDTIAKRHGVSFSQYLILKQIVENDCNEPSLLAKAFAISRPAMSRKLTVLFRNGKIKKLYNLKDEDQRITSL
>NZ_CP022709.1|WP_025016098.1|1719861_1721781_+|hypothetical-protein
MNREKGFRKVLLFGLALYVVGFGLGQDVTHSYATEASSDATLTSQLSSDSESTSSQSSSETLASETPKIAPETKGESTNPVKVMPSLAKTQTPVTQKVARAATTYKIQDLIDQGGVKTTVTWDIYSQSEDDISQGYTGTYYPKVIKFSVLPNNVLQPGDTISFSVLRYTGKLSGQGPVTMASVSLRELGQYDGKSLVLGSEYVPDKAVDASSDLPKSSGGVATLTNETTPDYTAAYAGSTINGTKSSVTVIPATHFNGFQVTNAAVGSDKKGTLTLSGYTKDQTYFQSALDGTPNLKGVPTANYVRIYRIDKESAQNINKVSFDLKTYMPALMPDGQHMAAKAGTTGPMLFIKAPAAVPINNSGSVAADATDDEIIAKTSPQTYGVLHNSDGSMTLYLNYGNLTRPYELPVDTITKGVMNNSWDGTQEGLDYALNRLSNNNYSALATSTYFTMNISFNDPSIENTVQATYKDTLNNTETINQPSSPPSASTDGQTTIKVHYADQNGKYIKPIETHYGWPDTDKLQITTQDLTIPGYTLDKSNLPKGADPDTGALTLSYPKEAGKVDDILYRFIQNKQKIDVTYVDDTTGKQLATDTMSGVVDENSKYNTQTKLAAYEKQGYQLVSDETNGATLLFSDQD
>NZ_CP022709.1|WP_094365873.1|1721790_1722780_+|hypothetical-protein
MHLKHAIKAAPDESKQVKRTIHYRYQSNKQAAPDVVDKITFTRHDQIDQVTNQSIGFTKWVSTEGTTTFAKQTSPVIKGYTADQLTVPAVENITQDSADITATVTYTGQAQKATVTYQRSDNQAVIQADQLTGVSGQISVYRTDATLAALADKGYTVADNPYPSDGLVFDDDVAVDQNVTVLLNYNPYYNRVYFKSVPSEMDFGQHTLASTTESYQPTVNQALSIQDERALGSKWTLKAALVQPFTGDTQKAPLEGDLTYQRADQLPTMITAQSTIIATTTTTSHDPVDISGQWQNQLGPQLVVPVGGALIDQYAAQVEWTLEDGVANE
>NZ_CP022709.1|WP_025016096.1|1722911_1723214_+|LPXTG-cell-wall-anchor-domain-containing-protein
MRWLKNKSKFVVLMLIIGSGLIVVNPTHTSANAQTATKSVARVGFYETGQPHKQAPIQTETKQQARLPQTGTSSVGLSTIVGIVLLIGSLGLFKQRRGNF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

94334 : 103953

Streptococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094365655.1\|94334_97187_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.9e-305	54.9
WP_016264747.1\|97308_97845_+	DUF308 domain-containing protein	NA	NA	NA	NA
WP_094365656.1\|97970_98855_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-08	27.2
WP_016264749.1\|98851_99886_+	YvcK family protein	A1IMD5	Streptococcus_phage	9.0e-95	54.8
WP_094365657.1\|99888_100833_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	3.8e-52	39.0
WP_035146456.1\|100924_101380_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_035146459.1\|101494_102019_-	DsbA family protein	NA	NA	NA	NA
WP_025016311.1\|102243_102828_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.5e-51	53.4
WP_025016310.1\|103371_103953_-	glycoside hydrolase family 73 protein	A0A249Y0X5	Enterococcus_phage	9.7e-22	41.0

DBSCAN-SWA_2

209724 : 218018

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_035146568.1\|209724_211020_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.8e-15	30.6
WP_011374364.1\|211132_211858_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	9.2e-38	39.9
WP_016264839.1\|211850_212111_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_035146570.1\|212107_212794_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_035146572.1\|212783_215009_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.0e-151	41.1
WP_035146574.1\|214984_216418_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.9e-51	33.9
WP_094365686.1\|216423_217452_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-64	44.3
WP_035146576.1\|217448_218018_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.0

DBSCAN-SWA_3

343932 : 393798

Lactobacillus_phage(39.39%)

terminase,tRNA,capsid,bacteriocin,integrase,tail,portal

attL 336407:336421|attR 373893:373907

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
336407:336421	attL	NA	NA	NA	NA
WP_076631886.1\|343932_345072_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_016264980.1\|345230_345881_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_035147215.1\|345896_347087_+	phosphopentomutase	NA	NA	NA	NA
WP_016264982.1\|347103_347808_+	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_016264983.1\|347829_349059_+	nucleoside transporter	NA	NA	NA	NA
WP_035147217.1\|349082_350357_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.1e-24	24.9
WP_035147221.1\|350384_351338_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_094365696.1\|351356_352655_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	1.4e-121	54.0
WP_035147226.1\|352891_354226_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011374509.1\|354379_355039_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_035147229.1\|355050_355710_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_035147232.1\|355715_358244_+	ATP-dependent RecD-like DNA helicase	A0A1P8DII4	Virus_Rctr197k	2.5e-42	29.3
WP_011374512.1\|358286_359498_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_035147235.1\|359558_359798_-	hypothetical protein	NA	NA	NA	NA
WP_056948400.1\|359800_360895_-\|integrase	site-specific integrase	Q9ZXG6	Leuconostoc_phage	2.0e-44	36.1
WP_094365697.1\|361075_361669_-	DUF5067 domain-containing protein	Q6SEF8	Lactobacillus_prophage	2.9e-37	51.4
WP_056948404.1\|361763_362432_-	LexA family transcriptional regulator	A6M973	Geobacillus_virus	8.8e-35	38.8
WP_056948406.1\|362616_362829_+	helix-turn-helix transcriptional regulator	J7KBP9	Streptococcus_phage	5.8e-17	63.6
WP_094365894.1\|362846_363611_+	phage antirepressor KilAC domain-containing protein	A0A0A7DN31	Lactobacillus_phage	2.2e-66	61.0
WP_157697944.1\|363624_363786_+	hypothetical protein	NA	NA	NA	NA
WP_094365698.1\|363772_364318_-	hypothetical protein	NA	NA	NA	NA
WP_035147721.1\|364407_364635_+	hypothetical protein	NA	NA	NA	NA
WP_035147719.1\|364634_364952_+	hypothetical protein	D7RWM6	Brochothrix_phage	7.7e-05	36.5
WP_094365699.1\|364948_365128_+	hypothetical protein	NA	NA	NA	NA
WP_129584131.1\|365234_365507_+	hypothetical protein	NA	NA	NA	NA
WP_085391716.1\|365509_366142_+	ERF family protein	A0A1P8BKZ7	Lactococcus_phage	1.0e-08	36.4
WP_094365700.1\|366144_366831_+	hypothetical protein	U5U4M2	Lactobacillus_phage	8.7e-54	47.3
WP_172826495.1\|367004_367562_+	conserved phage C-terminal domain-containing protein	A0A1P8BKK3	Lactococcus_phage	1.4e-22	53.7
WP_094365702.1\|367542_368379_+	ATP-binding protein	O03914	Lactobacillus_phage	2.9e-67	52.4
WP_094365703.1\|368487_368901_+	RusA family crossover junction endodeoxyribonuclease	A8YQM5	Lactobacillus_phage	5.6e-32	50.7
WP_094365704.1\|368890_369103_+	hypothetical protein	NA	NA	NA	NA
WP_094365705.1\|369114_369588_+	single-stranded DNA-binding protein	A0A2D1GPB7	Lactobacillus_phage	3.5e-46	61.8
WP_094365706.1\|369600_370314_+	hypothetical protein	NA	NA	NA	NA
WP_094365707.1\|370326_371160_+	hypothetical protein	NA	NA	NA	NA
WP_099960230.1\|371297_371636_+	hypothetical protein	NA	NA	NA	NA
WP_094365709.1\|371741_372071_+	hypothetical protein	NA	NA	NA	NA
WP_157697945.1\|372074_372227_+	hypothetical protein	NA	NA	NA	NA
WP_094365710.1\|372304_372736_+	hypothetical protein	O03925	Lactobacillus_phage	5.9e-32	49.6
WP_094365711.1\|373040_373994_+	hypothetical protein	NA	NA	NA	NA
373893:373907	attR	NA	NA	NA	NA
WP_094365712.1\|374016_374496_+	hypothetical protein	NA	NA	NA	NA
WP_076632024.1\|374996_375308_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_157697946.1\|375539_375713_+	hypothetical protein	NA	NA	NA	NA
WP_094365713.1\|375712_376198_+\|terminase	terminase small subunit	O03926	Lactobacillus_phage	1.2e-38	54.1
WP_094365714.1\|376175_377510_+\|terminase	PBSX family phage terminase large subunit	A4L7R3	Lactococcus_phage	1.2e-144	55.7
WP_157697947.1\|377569_379042_+\|portal	phage portal protein	Q938L2	Temperate_phage	1.4e-120	48.2
WP_085391420.1\|379041_380166_+\|capsid	phage minor capsid protein	U3PFU0	Lactobacillus_phage	3.0e-59	36.3
WP_157697948.1\|380259_380832_+	phage scaffolding protein	O03931	Lactobacillus_phage	4.4e-11	43.5
WP_035145507.1\|380833_381700_+	hypothetical protein	U3PDP8	Lactobacillus_phage	7.3e-98	61.3
WP_094365715.1\|381767_381989_+	hypothetical protein	NA	NA	NA	NA
WP_094365716.1\|381997_382402_+	hypothetical protein	C5IUJ7	Streptococcus_phage	2.7e-10	32.3
WP_094365717.1\|382394_382739_+	hypothetical protein	O03932	Lactobacillus_phage	2.6e-06	31.2
WP_094365895.1\|382747_383074_+\|capsid	capsid protein	O03933	Lactobacillus_phage	1.5e-24	49.6
WP_085391736.1\|383073_383466_+\|capsid	capsid protein	Q5YA65	Bacillus_phage	8.5e-30	45.0
WP_094365718.1\|383476_383932_+\|tail	phage tail protein	A0A1S5SEC5	Streptococcus_phage	7.8e-35	55.1
WP_094365719.1\|384071_384536_+	hypothetical protein	NA	NA	NA	NA
WP_094365720.1\|384546_385149_+	hypothetical protein	Q938K4	Temperate_phage	9.7e-25	34.2
WP_094365721.1\|385141_388321_+	hypothetical protein	Q77MU4	Lactococcus_phage	6.5e-11	70.0
WP_094365722.1\|388304_389030_+\|tail	phage tail family protein	A0A1B2APY0	Phage_Wrath	8.6e-52	41.9
WP_094365723.1\|389029_390544_+\|tail	phage tail protein	A0A1B2APX2	Phage_Wrath	2.4e-80	39.3
WP_094365724.1\|390543_392307_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_035147518.1\|392411_392678_+	hypothetical protein	NA	NA	NA	NA
WP_094365725.1\|392674_392884_+	hypothetical protein	A0A2H4IZQ3	uncultured_Caudovirales_phage	1.3e-05	49.2
WP_094365726.1\|392880_393798_+	N-acetylmuramoyl-L-alanine amidase	Q9MCC8	Lactobacillus_phage	3.0e-57	61.8

DBSCAN-SWA_4

587709 : 595105

Staphylococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025015768.1\|587709_588555_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	7.7e-20	44.2
WP_035145821.1\|588751_589252_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	3.5e-28	38.7
WP_016265161.1\|589262_590213_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.6e-122	64.3
WP_035145823.1\|590359_592249_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.3e-48	29.1
WP_011374705.1\|592361_592823_-	hypothetical protein	NA	NA	NA	NA
WP_035145825.1\|592891_594085_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	2.0e-42	50.0
WP_016265164.1\|594232_595105_+	YitT family protein	M1Q1P6	Streptococcus_phage	4.8e-57	41.5

DBSCAN-SWA_5

750183 : 762240

Enterococcus_phage(30.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094365751.1\|750183_751556_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	4.9e-32	39.2
WP_035147736.1\|751639_752338_-	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	1.7e-17	46.4
WP_011374858.1\|753006_753258_-	hypothetical protein	NA	NA	NA	NA
WP_094365752.1\|753485_753860_-	hypothetical protein	E3W8I0	Leuconostoc_phage	9.0e-05	32.7
WP_035147731.1\|753852_755157_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.3e-85	39.7
WP_052039308.1\|755156_755402_-	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	1.8e-06	41.2
WP_085391464.1\|755421_755796_-	hypothetical protein	NA	NA	NA	NA
WP_035147736.1\|755822_756521_-	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	1.7e-17	46.4
WP_016265285.1\|756763_758806_-	KUP/HAK/KT family potassium transporter	M1IAJ4	Acanthocystis_turfacea_Chlorella_virus	3.0e-70	35.7
WP_011374865.1\|758963_759137_+	hypothetical protein	NA	NA	NA	NA
WP_035146208.1\|759269_759749_+	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	1.1e-15	35.4
WP_094365753.1\|759800_761174_-	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	6.6e-45	30.2
WP_016265287.1\|761520_762240_-	aquaporin family protein	M1HQB9	Paramecium_bursaria_Chlorella_virus	2.4e-22	30.2

DBSCAN-SWA_6

787724 : 841744

unidentified_phage(12.5%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094365768.1\|787724_789096_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	9.9e-33	41.3
WP_056948755.1\|789178_790045_-	glucose transporter GlcU	NA	NA	NA	NA
WP_056948756.1\|790333_790942_-	VanZ family protein	NA	NA	NA	NA
WP_056948758.1\|791154_792213_+	glycosyltransferase	NA	NA	NA	NA
WP_094365769.1\|792316_794494_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.2e-167	49.1
WP_016265316.1\|794543_795005_-	hypothetical protein	NA	NA	NA	NA
WP_016265317.1\|794998_795751_-	hypothetical protein	NA	NA	NA	NA
WP_094365771.1\|796096_797026_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9
WP_025016356.1\|798482_799718_+	cytosine deaminase	NA	NA	NA	NA
WP_025016355.1\|799768_801205_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.7e-30	33.6
WP_016265321.1\|801204_801945_-	response regulator transcription factor	W8CYM9	Bacillus_phage	6.3e-34	35.3
WP_011374914.1\|802230_802458_+	hypothetical protein	NA	NA	NA	NA
WP_025016354.1\|802592_803357_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_035146153.1\|803493_804885_+	amino acid permease	NA	NA	NA	NA
WP_011373852.1\|805893_806814_-\|transposase	IS30-like element ISLsa1 family transposase	Q9MBM9	Staphylococcus_prophage	9.2e-51	38.2
WP_094365772.1\|807438_808590_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	3.1e-27	27.6
WP_094365773.1\|808709_810542_-	molecular chaperone DnaK	A0A2P1EIW2	Megavirus	8.3e-136	47.5
WP_016265326.1\|810570_811164_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_025016350.1\|811179_812238_-	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_094365774.1\|812418_813066_-	CatB-related O-acetyltransferase	M1HS53	Paramecium_bursaria_Chlorella_virus	3.6e-09	30.6
WP_035146146.1\|813577_814717_-	oxygen-independent coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_016265330.1\|814716_815670_-	riboflavin biosynthesis protein RibF	NA	NA	NA	NA
WP_025016347.1\|815688_816606_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_094365898.1\|816741_817482_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_025016345.1\|817672_818191_-	hypothetical protein	NA	NA	NA	NA
WP_061827042.1\|818183_819503_-	glycosyltransferase	NA	NA	NA	NA
WP_011374944.1\|819749_820106_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_016265335.1\|820128_822942_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	2.3e-20	24.2
WP_011374946.1\|822959_823265_-	ribosomal L7Ae/L30e/S12e/Gadd45 family protein	NA	NA	NA	NA
WP_025016343.1\|823261_823561_-	YlxR family protein	NA	NA	NA	NA
WP_011374948.1\|823575_824793_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_016265337.1\|824811_825285_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_094365775.1\|825425_826436_-	lactate dehydrogenase	NA	NA	NA	NA
WP_094365776.1\|826451_827492_-	AEC family transporter	NA	NA	NA	NA
WP_094365777.1\|827697_828048_+	DUF2200 domain-containing protein	NA	NA	NA	NA
WP_094365778.1\|828123_828504_-	hypothetical protein	NA	NA	NA	NA
WP_094365779.1\|828528_829500_-	restriction endonuclease	NA	NA	NA	NA
WP_094365780.1\|829766_830126_+	hypothetical protein	NA	NA	NA	NA
WP_094365782.1\|830213_831143_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	5.5e-19	29.5
WP_157697949.1\|831108_831906_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_094365784.1\|831971_833846_-	DEAD/DEAH box helicase	A0A0K1LKG3	Staphylococcus_phage	1.8e-08	23.9
WP_094365785.1\|833832_835104_-	hypothetical protein	NA	NA	NA	NA
WP_094365786.1\|835093_838015_-	type III restriction-modification system endonuclease	Q71TG1	Escherichia_phage	1.2e-80	29.3
WP_094365787.1\|838014_840138_-	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	2.7e-69	30.2
WP_094365899.1\|840221_840479_-	plasmid replication protein	NA	NA	NA	NA
WP_154255156.1\|840596_841439_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.3e-152	97.5
WP_094365789.1\|841492_841744_-\|transposase	transposase	Q6J1X3	Lactobacillus_phage	7.8e-37	94.0

DBSCAN-SWA_7

862340 : 870449

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025016406.1\|862340_864086_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.2e-46	27.7
WP_011374970.1\|864227_864458_-	YneF family protein	NA	NA	NA	NA
WP_011374971.1\|864538_864781_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_011374972.1\|864915_865530_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	1.1e-15	58.2
WP_011374973.1\|865663_866182_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.4e-26	41.3
WP_025016402.1\|866205_868518_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.8e-77	30.9
WP_061827025.1\|868662_869655_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	3.8e-50	37.0
WP_011374976.1\|869740_870106_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_011374977.1\|870122_870449_+	heavy metal-binding domain-containing protein	M4STD1	Rhodobacter_phage	5.4e-06	34.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP022710

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022710_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022710_1

60773-60929

Orphan

Consensus_repeat	Method
AAAGTAAACATGTATACATTAGTACA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP022710_1

>merge|NZ_CP022710|1|60773-60929|PILER-CR
AATGTAAACATGTATACATTGGAAGGCACGATAAATATTTTGTTTACTTGTATTAATGTAAAAAAGTAAATATGTATACATTTTTACACATAATAATACCTATAAATAAGCAATACACAACTTTTAATACTAAAGTAAACATGTATACATTAGTACA

>NZ_CP022710|1|1|60773-60929|PILER-CR
AATGTAAACATGTATACATTGGAAGG	CACGATAAATATTTTGTTTACTTGTATTAATGTAAAAAAGTA
AATATGTATACATTTTTACACATAAT	AATACCTATAAATAAGCAATACACAACTTTTAATACTAAAGTA
AACATGTATACATTAGTACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022710.1\|WP_016265853.1\|60998_61814_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NZ_CP022710.1\|WP_014216295.1\|52302_52665_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274860
NZ_CP022710.1\|WP_061827385.1\|54075_56139_-\|MobA/MobL-family-protein	unknown	unknown	gnl\|CDD\|367473
NZ_CP022710.1\|WP_016265837.1\|66333_66909_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP022710.1\|WP_099769415.1\|67348_68418_-\|IS3-like-element-IS1520-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP022710.1\|WP_016265827.1\|68855_69518_-\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672
NZ_CP022710.1\|WP_061827406.1\|64553_65126_-\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NZ_CP022710.1\|WP_061827405.1\|63770_63992_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022710.1\|WP_061827384.1\|56910_57732_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NZ_CP022710.1\|WP_035145350.1\|61806_62157_+\|DUF5388-domain-containing-protein	unknown	unknown	gnl\|CDD\|375154
NZ_CP022710.1\|WP_016265839.1\|64004_64529_-\|GrpB-family-protein	unknown	unknown	gnl\|CDD\|377252
NZ_CP022710.1\|WP_057904517.1\|56642_56921_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022710.1\|WP_035145878.1\|49647_51663_-\|DUF87-domain-containing-protein	unknown	unknown	gnl\|CDD\|274279
NZ_CP022710.1\|WP_076639168.1\|56392_56620_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022710.1\|WP_039098895.1\|53023_53638_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022710.1\|WP_016265852.1\|59451_60450_-\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|369151
NZ_CP022710.1\|WP_061827386.1\|52686_53022_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|374896
NZ_CP022710.1\|WP_025085233.1\|51674_52334_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|273346
NZ_CP022710.1\|WP_011373852.1\|62785_63706_-\|IS30-like-element-ISLsa1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP022710.1\|WP_112234043.1\|65134_66204_-\|IS3-like-element-IS1163-family-transposase	unknown	unknown	gnl\|CDD\|222853

Protein	Function_ID	Function_description	E-value
NZ_CP022710.1\|WP_016265853.1\|60998_61814_+\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	4.14334e-51
NZ_CP022710.1\|WP_014216295.1\|52302_52665_-\|hypothetical-protein	gnl\|CDD\|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0.00203
NZ_CP022710.1\|WP_061827385.1\|54075_56139_-\|MobA/MobL-family-protein	gnl\|CDD\|367473	pfam03389, MobA_MobL, MobA/MobL family. This family includes of the MobA protein from the E. coli plasmid RSF1010, and the MobL protein from the Thiobacillus ferrooxidans plasmid PTF1. These sequences are mobilisation proteins, which are essential for specific plasmid transfer.	2.82107e-102
NZ_CP022710.1\|WP_099769415.1\|67348_68418_-\|IS3-like-element-IS1520-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.9979e-35
NZ_CP022710.1\|WP_061827406.1\|64553_65126_-\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.08322e-09
NZ_CP022710.1\|WP_016265827.1\|68855_69518_-\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	4.4669e-78
NZ_CP022710.1\|WP_061827384.1\|56910_57732_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	4.96691e-05
NZ_CP022710.1\|WP_011373852.1\|62785_63706_-\|IS30-like-element-ISLsa1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.37768e-76
NZ_CP022710.1\|WP_016265852.1\|59451_60450_-\|replication-initiator-protein-A	gnl\|CDD\|369151	pfam06970, RepA_N, Replication initiator protein A (RepA) N-terminus. This of family of predicted proteins represents the N-terminus (approximately 80 residues) of replication initiator protein A (RepA), a DNA replication initiator in plasmids. Most proteins in this family are bacterial, but archaeal and eukaryotic members are also included.	4.11678e-29
NZ_CP022710.1\|WP_035145878.1\|49647_51663_-\|DUF87-domain-containing-protein	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	5.24902e-29
NZ_CP022710.1\|WP_016265837.1\|66333_66909_-\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	3.44596e-48
NZ_CP022710.1\|WP_016265839.1\|64004_64529_-\|GrpB-family-protein	gnl\|CDD\|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	2.15922e-58
NZ_CP022710.1\|WP_061827386.1\|52686_53022_-\|conjugal-transfer-protein	gnl\|CDD\|374896	pfam16943, T4SS_CagC, Cag pathogenicity island, type IV secretory system. T4SS_CagC is a family of putative pathogenicity island, type IV, conjugal DNA-protein transfer, secretory system proteins from Gram-negative bacteria.	1.14159e-43
NZ_CP022710.1\|WP_025085233.1\|51674_52334_-\|conjugal-transfer-protein	gnl\|CDD\|273346	TIGR00929, CAG_pathogenicity_island_protein_23, type IV secretion/conjugal transfer ATPase, VirB4 family. Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).	0.00134284
NZ_CP022710.1\|WP_035145350.1\|61806_62157_+\|DUF5388-domain-containing-protein	gnl\|CDD\|375154	pfam17363, DUF5388, Family of unknown function (DUF5388). This is a family of unknown function found in Lactobacillales.	5.187e-25
NZ_CP022710.1\|WP_112234043.1\|65134_66204_-\|IS3-like-element-IS1163-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.95585e-45

>NZ_CP022710.1|WP_016265852.1|59451_60450_-|replication-initiator-protein-A
MDNQLNYYNIKREYALKFFQVPKVFMTNDKYKKLSAEAKLAFAILSDRLQLSIKNHWFDKAGNIYFIYTGEQLEQILGCGHSKITSIKKELTEAQLLVMKRMGQGKANRMYLLGPEITDNDIYGIDQLETAENPLAEEVVNIDLPTSMNDGQPETLDKSRLLKNSNLDYRKTVTSDTDINNTEYLKTLNTDTKKTDTLTDSPQNIKQLQDAALFEVQLENDNIFSKQQLLALKLLSNGDFELFCTVQKTILRAKKQALNSHQIQSSLFDLQDEDIDQPVYDALMRIVQQVRLGAIQDLNSYVFSTMFDQFEQLGSKRAITAYKASGATITWE
>NZ_CP022710.1|WP_061827384.1|56910_57732_-|Fic-family-protein
MTKTQAYMDKYQFTVAENKRFARTNFTKLVHTSARFEGVNTTLPQTQTIMDGMSVAGVPVEDILTIVNLKRGWQYITDQNSSLTLTMEKQINKIVAAEDALVPGELRQGKGGVDLGSEDFFEPPLINEEQEQSFLQKILADPQTTTTDKALTVMYHNMRQQIFWDGNKRTATLSANKIMIDGGAGLINVPLDKWDQWNELIANYYRTNDMAKIKRWTYDNGIQGLQIRANLELKSVEDEIGKRIQEQLKDFADQNPEIKPKNDPENKNDRPSY
>NZ_CP022710.1|WP_057904517.1|56642_56921_+|hypothetical-protein
MSNQYEKLVEQQARLKQKIEREDFKLRQSKYYESRQDRKARSRRLIQKGALLEKYFQADNLSVEQTEELLKTFADYVNAHKPNKLKNDQPNN
>NZ_CP022710.1|WP_076639168.1|56392_56620_+|hypothetical-protein
MIGGIIMSQSNLEKQEAKLKALNQKIKDEKNKIEQRLGKQIISQANLDYANLSNDQIKLLAKQFSEFLKVKSVDH
>NZ_CP022710.1|WP_061827385.1|54075_56139_-|MobA/MobL-family-protein
MAIFHMSFQNISAGKGRSAIAGASYRSGEKLFDQKEGRSYFYARSVMPESFILTPKNAPEWASDREKLWNEVERKDRRVNSRYAKEFNVALPVELSEDEQKELLTKYVQENFVDEGMVADVAIHRDHPDNPHAHVMLTNRPFNPDGTWGLKSKRENILDENGNKTYTGNSRFPRSRKVWLVDWDKKEKITEWRHNWAASVNQVLEQKNIPDRISEKSFIEEGIDDIPMQHEGINSKRHERKEFNQQVKDYRKAKASYKNNQEKVINRGHLDSLSKHFSFNEKRVVNELSHELKTYISLESLDDKRRMLFNWKNSTLIKHAVGEDVTKQLLTINQQESSLKKADELLNKVVDRTTKKLYPELNFEQTTQAERRELIKETDSEQTVFKGSELNERLMNIRDDLLTQQLLTFTKRPYVGWKLLMQQEKEVKIELKYTLMIHDDNLESLERVDQGLLEKYSPTEQQKITRAVKDLRAIMAVKQVIQTQYHEVLKRAFPKGDLDGLPLIKQEQAYTAVMYYDPVLKPCQAETIEQWQANPPQVFSPQEHQQGLAYLSGQLSLDQLENHHLQRVLKHDGTKQLFFGECKADPTIKNSQIEKIQKQLKGQQAKDDQYRKANIGHYQPLNYKPVSPDYYLKTAFSNAIMTALYARDEDYQRQKQAQGLKETEWEMTKKQRQHQTRNRHEDGGMHL
>NZ_CP022710.1|WP_039098895.1|53023_53638_-|hypothetical-protein
MKVESWQGINGKLLHDDQKAIVVDDDQKLTELKQLQAILDQDGQPIDEVRQAMIKKTVKRQLKIEPLKLSGWFNRHQDSQNAKKTEKLVSDKPTHQYKQIKNEMTFFGESFLEGFLGFYGLKVDNALGRYEHNLHVLETQELGQSEKEYYLATSENGRVKLATDPLPSQQIAEEQLDKFYQREPEQTQAEQVQLRSSEDEGKEE
>NZ_CP022710.1|WP_061827386.1|52686_53022_-|conjugal-transfer-protein
MKFRKMKALATTGATAIYLGLMNAQVVLAADGGEVKSKLTQAGKTIQGILTGLVVLVGICVALFIIIKRMPDADDPREKSEVYHAVGRVAGLVALAAAIIWLLPWVYSLFT
>NZ_CP022710.1|WP_014216295.1|52302_52665_-|hypothetical-protein
MKKGKEFIFPENVDKDYGIWKDYTLKDFGYAALAGLVGLIFIAIPPYGLILVLIKIVIVVLAMTIVMAILTIRPVAARKNIKVRDNFKLKRRYANGQKLFYLKPKKRGELNAFEEEQNRQ
>NZ_CP022710.1|WP_025085233.1|51674_52334_-|conjugal-transfer-protein
MRLKKNKTANKSARLDWDYQPPKINGGKETIDDMSLVVGMYGNYEVTKTGNLVGILEVSGINLDLLNETEQQDVFEDYGAFLMSTLGEGVDDTLQFLEPTIPVNMTAYLNGLKRRYLTLQKDHPEQQFKIQLMASYLDHFTKVQESKNMTTKQHLLIVKVPIKDKSVKSLSLAVTHLDEKIEQVKRDIENALTDFDVTAKVLTSQEVQEILKNLINFNG
>NZ_CP022710.1|WP_035145878.1|49647_51663_-|DUF87-domain-containing-protein
MSFGDKVIDLFMPTKKESQQNSEPAVNKQKPEVEDFTKLIDRDSLHSLFPFSWEQYPTYVQSGENFIRVLAIADYPKRVYGNWLSELKRKKGVIDIVQYIDSASNNSMITYYKKTIQNKEAQKLNTFDPYKKKILQNYIDSANMQLDKYLDNSTTFVYQHMLVYLRANSLAELDDLTENVKNTLIKLQMKPLVPVKATFQAFWSTMPINENLMGDYTYKESNTEVASSMFPFDDAEILDLKPRSDIEGVNKDTNSLIAVDMLDRNKTLNQNQVIIGTSGVGKTTYMIQKILRYAIQDYQIYIIDPENEYTKIVEALGGAVLHLTSNAKYKINPLQIFSEEILSADEAVTNLDLLVKDKIQRLKGFFEVLKTGITQVELAILDDVVKQAYVNSGVLKYSRLKEIKDDQWPTLSNVYDELEKLADKDADKFGRVKDFYYILGSYTRGSNSLFDGHTNVNLKGKIISFDLKPLQSEQEVQSAAYLNTFQYLWDEITKDRHNRKKLFVDEFHFLTLHKAAATFFHQAYKRFRKYNAGAIAGTQQIQDVIEGTTDTGQNIGEAIIGNSYTKVFFGLDGKGVDDVITKLRMTFSDKEKKLLERRRQGEALMIYGSQRAFMKVDLTEEELRLIDPEAYQEKYNCETAIQPDYQKRVVLTPSEVDALTTTEEEGGTLNE
>NZ_CP022710.1|WP_016265853.1|60998_61814_+|AAA-family-ATPase
MSSRVITFGNFKGGTGKTTTSTMVGIELARRNLKTLLVDLDPQGNATNLYLKTKENVDNEIVSFNKTLMAGIKDQDLSQTIINILPNLDVLPSSADFSLYPRFMETVSSDYNERVWYFSKLMKEFKEKYDYILIDIPPTISLITDSALYASDYCVIVLQTQERSLQGAEAFINYMQEQVIDTFKAPTLDLIGILPVLLKNGAPVDNSTLEVAKELFGSENIFDITIKNMERLKRYDVTGVMFKDQFDHAVQNVYEKVTTEMISRIGAIENG
>NZ_CP022710.1|WP_035145350.1|61806_62157_+|DUF5388-domain-containing-protein
MGSLLNSNRVKSNSLDRGKRIEPENSMSIKDLSNPGEQSKSSKIESVTYYANVRINNHIKNKAEALSIIGVAKSQKDAIDRALDSFVEQLSDDEKRSFKNQLATLEAKDVKMKSEK
>NZ_CP022710.1|WP_011373852.1|62785_63706_-|IS30-like-element-ISLsa1-family-transposase
MGTSTLSRFQRGALAQLVNEGNKSYQVMADALGVAKATISYELDRVKPYDPELAQQDADRKRRNCGRRSMLTAALATLITNHLRLTWSPETIAAAYNLSTASIYNWLNRGWLPFKLTDLPNRNVRQHRVSENRGKFTSGTSIEQRPTTVNQRLAFGHWEVDTVLSSRSESRSCLVTFVERKTRLLWAIKAPNRTAKALNTAFGKFMGAFGPQVKSITVDHGKEFANYQALEQDYQIKVYFCHPYSPWERGSNEYFNRRLRWFFPKKTNFSQVTTDEILAALELINQRPLKIHHQQTAIERFRACSD
>NZ_CP022710.1|WP_061827405.1|63770_63992_-|hypothetical-protein
MAICLIRYNRKYLPAIVTLFNSTIQRVNRKDYSQAELNEWIQSNPDFDLWHETLTSSYCLLAMANSIINPNRN
>NZ_CP022710.1|WP_016265839.1|64004_64529_-|GrpB-family-protein
MRVENVVVANYSEDWAKEFEKIKTDILKKISADIIRIEHVGSTSVEGLCAKPIIDIDIVIEDYSKFEAVKSGLASLGYEYEGDLGITEREAFSYEIDQKNQFMEHHIYVCPKHSVELNRHVTFRDHLRNNQPDCQKYGEIKRAAAKKFPTDIEGYLDMKGVVISEIYQRCGLLK
>NZ_CP022710.1|WP_061827406.1|64553_65126_-|pentapeptide-repeat-containing-protein
MPFIDIGAHIRKRIKLSYEHMASSKIELNEVKFENVELTNVKMTHSNFTNITFINCTFRHVNFSNSSFNNISMVDCDLDEVDFTQSEFDGIQFISSNFKQALFNKSNFIFTKYEDCQLIEVEFIRIKHKELSLTKCLLSKNNFLYTRLDGLNFSNLKLSDLLFSMDLISGMTITKEQAMTFFEELGVNVV
>NZ_CP022710.1|WP_112234043.1|65134_66204_-|IS3-like-element-IS1163-family-transposase
MKRYQDDFKASIVKMHREEKRSIRSLSEEYGVSPAAIHNWVKGAKSVELEDGTEVTSKEFKQLQKENQRLKEELEIFKSCGGVTGKALGRINCLVFIEDQLLRHRLSIILSALKLPRSTYYHWKRYQPSQHERVDNQLKEKIKLIWENNYRAYGYPRITMVLRKSGICVGSKRILRLMREMEIHSLMNRRFKKPGTHVDHSQRPNLIKHQPNARIWRADITYLELRPGTWVYLSSIYEPKVHQVLAFKIGRQMEATLVVETINQALEYHQKPQYFHSDMGSQYTSNEVETLLERHQISHSYSKQGYPYDNGPIEAFHSLLKREFAFQTTFSNFEDLVIRTSNYISWFNSDRIRTSV
>NZ_CP022710.1|WP_016265837.1|66333_66909_-|recombinase-family-protein
MVKIYGYARVSTSSQNLEEQIAQLVDAGVDPKNIYSEKFTGTTTHRPIFDLLLNTISSGDTLVITKLDRFARNTREALNSIEPLLDQNISIKVLNLGTIENTPMGKMIVRTLLSVAEMERDMIVERTQAGKEYSKKHNSKFKEGRPKRKIGPHEMAIYEYYQNHSIKETTEAFNTSKATLFRIKQQIEIGV
>NZ_CP022710.1|WP_099769415.1|67348_68418_-|IS3-like-element-IS1520-family-transposase
MAIKYSNEFKESIVSLSQTGRSANSLAKEYNVSVSTVTKWIKQADPNNTKVLSSNERALIKENKRLKEELDIFKTSGGAHGKKLIIKGRALVLEVVNANLLAGHRITRILSVLKIPRSTYYDYLHWQPSRTERRRHLIKQEVLTAWLRYPMYGYPRLTILLNQQSDIHVSQRLVYQQMCELGIRSRMVKRINKPTTQTDYDQRPNLIKQLTDQSGILLTDITYIPLNHTWCYLASVYNPVTRRVIAYQLNTQMTKELATNVITQVMAQAVKPQIIHSDMGSQYTSDLFENTLSKYGIKHSYSRKGQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRISLVA
>NZ_CP022710.1|WP_016265827.1|68855_69518_-|beta-phosphoglucomutase
MKFEDIKGFAFDLDGVIADSARLHAKAWHQTADEVHSEWTPELAEALKGVSRMDSLEMILKAGGHENDYTEDEKVALATEKNTKYLKLVESLTPDDVLPGMKAFLDELKASGYKMSVASASKNAPAILKQLKITDYFEGVVDPAKLHAGKPDPEIFSLAAGVMDLAPEVVAGLEDSGAGIKSINAAGELSIGIGNQLMEADVRFADTSEVSLKNIKAKLG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	NZ_CP022710	Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence	60793-60834	0	1.0
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	NZ_KF559312	Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence	45113-45154	0	1.0
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	NZ_LT960778	Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence	1438-1479	0	1.0
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	NZ_LT907987	Lactobacillus sakei strain T332 plasmid p332A2, complete sequence	1438-1479	0	1.0
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	AP018700	Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome	35553-35594	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	NZ_AP017932	Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence	21965-22007	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	NZ_CP025207	Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence	34410-34452	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	NZ_CP022710	Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence	60861-60903	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	NZ_KF559312	Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence	45044-45086	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	NZ_LT960778	Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence	1369-1411	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	NZ_LT960782	Lactobacillus sakei strain J64 plasmid 2, complete sequence	1369-1411	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	NZ_LT907987	Lactobacillus sakei strain T332 plasmid p332A2, complete sequence	1369-1411	0	1.0
NZ_CP022710_1	1.2\|60867\|43\|NZ_CP022710\|PILER-CR	60867-60909	43	AP018700	Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome	35484-35526	0	1.0
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	NZ_LT960782	Lactobacillus sakei strain J64 plasmid 2, complete sequence	1438-1479	1	0.976
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	NZ_AP017932	Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence	21897-21938	1	0.976
NZ_CP022710_1	1.1\|60799\|42\|NZ_CP022710\|PILER-CR	60799-60840	42	NZ_CP025207	Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence	34342-34383	1	0.976

1. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to NZ_CP022710 (Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence) position: , mismatch: 0, identity: 1.0

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******************************************

2. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to NZ_KF559312 (Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence) position: , mismatch: 0, identity: 1.0

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******************************************

3. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to NZ_LT960778 (Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence) position: , mismatch: 0, identity: 1.0

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******************************************

4. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to NZ_LT907987 (Lactobacillus sakei strain T332 plasmid p332A2, complete sequence) position: , mismatch: 0, identity: 1.0

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******************************************

5. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to AP018700 (Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome) position: , mismatch: 0, identity: 1.0

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******************************************

6. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to NZ_AP017932 (Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

7. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to NZ_CP025207 (Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

8. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to NZ_CP022710 (Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

9. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to NZ_KF559312 (Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

10. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to NZ_LT960778 (Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

11. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to NZ_LT960782 (Lactobacillus sakei strain J64 plasmid 2, complete sequence) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

12. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to NZ_LT907987 (Lactobacillus sakei strain T332 plasmid p332A2, complete sequence) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

13. spacer 1.2|60867|43|NZ_CP022710|PILER-CR matches to AP018700 (Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome) position: , mismatch: 0, identity: 1.0

cataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
cataataatacctataaataagcaatacacaacttttaatact	Protospacer
*******************************************

14. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to NZ_LT960782 (Lactobacillus sakei strain J64 plasmid 2, complete sequence) position: , mismatch: 1, identity: 0.976

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
agaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
.*****************************************

15. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to NZ_AP017932 (Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence) position: , mismatch: 1, identity: 0.976

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggtacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******.***********************************

16. spacer 1.1|60799|42|NZ_CP022710|PILER-CR matches to NZ_CP025207 (Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence) position: , mismatch: 1, identity: 0.976

ggaaggcacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggtacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******.***********************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7466 : 19651

Enterococcus_phage(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015474701.1\|7466_7781_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	2.0e-13	41.0
WP_006844823.1\|7801_8125_+	thioredoxin family protein	NA	NA	NA	NA
WP_080280589.1\|8124_8259_+	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_006844822.1\|8343_9288_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	7.7e-77	47.9
WP_006844821.1\|9306_9954_+	DsbA family oxidoreductase	NA	NA	NA	NA
WP_015474696.1\|10115_11447_+	NAD(P)/FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-20	24.7
WP_052039314.1\|11579_11840_-	hypothetical protein	NA	NA	NA	NA
WP_094365905.1\|11882_12812_-\|transposase	IS30 family transposase	H7BW47	unidentified_phage	6.7e-25	34.4
WP_016265840.1\|12952_13903_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	3.2e-99	55.0
WP_061827404.1\|13917_14844_-	ribonucleotide-diphosphate reductase subunit beta	A0A2H4P8A9	Corynebacterium_phage	1.0e-36	32.1
WP_035147778.1\|14950_17098_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	2.7e-255	60.2
WP_172821868.1\|17125_17584_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_011373852.1\|17942_18863_-\|transposase	IS30-like element ISLsa1 family transposase	Q9MBM9	Staphylococcus_prophage	9.2e-51	38.2
WP_035147318.1\|19069_19651_-	recombinase family protein	M9Q1K0	Clostridium_phage	4.1e-20	34.9

DBSCAN-SWA_2

60998 : 69518

Enterococcus_phage(14.29%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016265853.1\|60998_61814_+	AAA family ATPase	F0PIG8	Enterococcus_phage	2.9e-56	45.5
WP_035145350.1\|61806_62157_+	DUF5388 domain-containing protein	NA	NA	NA	NA
WP_011373852.1\|62785_63706_-\|transposase	IS30-like element ISLsa1 family transposase	Q9MBM9	Staphylococcus_prophage	9.2e-51	38.2
WP_061827405.1\|63770_63992_-	hypothetical protein	NA	NA	NA	NA
WP_016265839.1\|64004_64529_-	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	2.5e-16	33.3
WP_061827406.1\|64553_65126_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_112234043.1\|65134_66204_-\|transposase	IS3-like element IS1163 family transposase	A0A1P8CWQ3	Bacillus_phage	1.4e-34	33.2
WP_016265837.1\|66333_66909_-	recombinase family protein	A0A0A8WIK3	Clostridium_phage	1.1e-33	45.2
WP_099769415.1\|67348_68418_-\|transposase	IS3-like element IS1520 family transposase	Q6J1X2	Lactobacillus_phage	6.3e-27	34.9
WP_016265827.1\|68855_69518_-	beta-phosphoglucomutase	A7ITQ4	Paramecium_bursaria_Chlorella_virus	1.7e-09	25.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022709

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP022710

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection