CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP023011	Enterococcus hirae strain FDAARGOS_234 chromosome, complete genome	4 crisprs	cas3,cas9,cas1,cas2,csn2,cas14j,csa3,DinG,DEDDh	0	7	217	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP023011_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023011_1

223192-223319

Orphan

Consensus_repeat	Method
CCAAGTATTGTTCATCATCTACTCACTTCGTTCTTAGTGATTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP023011_1

>merge|NZ_CP023011|1|223192-223319|CRISPRCasFinder
CCAAGTATTGTTCATCATCTACTCACTTCGTTCTTAGTGATTCATCATGCTTCGCTTGAGAGGGAACTTCGCTCACTCTGTTCGCCAAGTATTGTTCATCATCTACTCACTTCGTTCTTAGTGATTCA

>NZ_CP023011|1|1|223192-223319|CRISPRCasFinder
CCAAGTATTGTTCATCATCTACTCACTTCGTTCTTAGTGATTCA	TCATGCTTCGCTTGAGAGGGAACTTCGCTCACTCTGTTCG
CCAAGTATTGTTCATCATCTACTCACTTCGTTCTTAGTGATTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023011.2\|WP_095454061.1\|230602_231487_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|283645
NZ_CP023011.2\|WP_172595711.1\|222211_222574_-\|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl\|CDD\|234671
NZ_CP023011.2\|WP_010720157.1\|231730_232276_-\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
NZ_CP023011.2\|WP_094940221.1\|225956_226823_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP023011.2\|WP_094940220.1\|221088_221463_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_053765776.1\|215822_217352_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP023011.2\|WP_094940989.1\|228624_229194_+\|EndoU-domain-containing-protein	unknown	unknown	gnl\|CDD\|373068
NZ_CP023011.2\|WP_010720150.1\|223519_224209_-\|50S-ribosomal-protein-L1	unknown	unknown	gnl\|CDD\|180071
NZ_CP023011.2\|WP_094940219.1\|214691_215393_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|238693
NZ_CP023011.2\|WP_010720149.1\|222632_223136_-\|50S-ribosomal-protein-L10	unknown	unknown	gnl\|CDD\|234632
NZ_CP023011.2\|WP_010720158.1\|232375_232546_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|376355
NZ_CP023011.2\|WP_094940222.1\|227147_228188_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_094940223.1\|229213_230194_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_010720151.1\|224312_224735_-\|50S-ribosomal-protein-L11	unknown	unknown	gnl\|CDD\|234661
NZ_CP023011.2\|WP_010720090.1\|218021_218255_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_010720092.1\|220019_220697_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP023011.2\|WP_053765777.1\|218658_219843_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP023011.2\|WP_081127692.1\|221850_222066_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223456
NZ_CP023011.2\|WP_010720152.1\|225274_225943_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NZ_CP023011.2\|WP_080704604.1\|217694_217997_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091

Protein	Function_ID	Function_description	E-value
NZ_CP023011.2\|WP_172595711.1\|222211_222574_-\|50S-ribosomal-protein-L7/L12	gnl\|CDD\|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	8.58422e-44
NZ_CP023011.2\|WP_010720157.1\|231730_232276_-\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	4.49583e-84
NZ_CP023011.2\|WP_094940221.1\|225956_226823_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	3.98873e-100
NZ_CP023011.2\|WP_010720158.1\|232375_232546_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|376355	pfam00584, SecE, SecE/Sec61-gamma subunits of protein translocation complex. SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.	4.32122e-12
NZ_CP023011.2\|WP_053765776.1\|215822_217352_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	8.97729e-169
NZ_CP023011.2\|WP_094940989.1\|228624_229194_+\|EndoU-domain-containing-protein	gnl\|CDD\|373068	pfam14436, EndoU_bacteria, Bacterial EndoU nuclease. This is a bacterial virion of EndoU nuclease. It is found at C-terminal region of polymorphic toxin proteins.	3.97591e-13
NZ_CP023011.2\|WP_010720150.1\|223519_224209_-\|50S-ribosomal-protein-L1	gnl\|CDD\|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	1.55211e-146
NZ_CP023011.2\|WP_094940219.1\|214691_215393_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	5.26309e-114
NZ_CP023011.2\|WP_010720149.1\|222632_223136_-\|50S-ribosomal-protein-L10	gnl\|CDD\|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	2.17032e-67
NZ_CP023011.2\|WP_010720151.1\|224312_224735_-\|50S-ribosomal-protein-L11	gnl\|CDD\|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	9.72997e-95
NZ_CP023011.2\|WP_095454061.1\|230602_231487_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	8.17099e-79
NZ_CP023011.2\|WP_010720092.1\|220019_220697_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	5.75433e-13
NZ_CP023011.2\|WP_053765777.1\|218658_219843_-\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.57456e-70
NZ_CP023011.2\|WP_081127692.1\|221850_222066_-\|hypothetical-protein	gnl\|CDD\|223456	COG0379, NadA, Quinolinate synthase [Coenzyme metabolism].	0.00392704
NZ_CP023011.2\|WP_010720152.1\|225274_225943_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	3.8878e-76
NZ_CP023011.2\|WP_080704604.1\|217694_217997_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	3.5733e-18

>NZ_CP023011.2|WP_010720149.1|222632_223136_-|50S-ribosomal-protein-L10
MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRKQLRDANVEMKVIKNSILSRAAKKAGLEGLDEVFTGPTAVAFSNEDVVAPAKIMDEFAKEAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVADKEDGDAA
>NZ_CP023011.2|WP_172595711.1|222211_222574_-|50S-ribosomal-protein-L7/L12
MNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAAVAAGGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSKEEAEELKAKLEEVGASVTVK
>NZ_CP023011.2|WP_081127692.1|221850_222066_-|hypothetical-protein
MELYKMLSPADIQFLKTKLNVIIQDRNYTDDEVVQIYDKIEDFHILQSFDENYNLSEDGKHALDILYLDIW
>NZ_CP023011.2|WP_094940220.1|221088_221463_-|hypothetical-protein
MKKFDSRYIIGVFLVLFILIGSVEFILKGHHSFTLNEIYFRVPIVVVGMVEMLPNEKGWGTFRVLFLVFLSDYLLKKIFDHFGLEEITLTFIPYLIILGILLVIFFARLTIKKDFFKHIKKENK
>NZ_CP023011.2|WP_010720092.1|220019_220697_-|TVP38/TMEM64-family-protein
MKTKKLRVFLIIIGLLLILFIGYRLYLEYQTDIQMFLDPKTSRQALLDQIRSHGFRTALFLILLISVMCAVPGIPTSVIGVLVGLSYGPLLGTLINVSGNAFGNMLSIFLMQHLKLFDHSKKSNRWVTAIRNMKHPKIGVMVGYMVPVIPSSVINFAAMTLNLQIRDIILSIVIGVIPSSILYACGGEALFHGYSKTALLLVASVLILTLLVVIIYKDRRKRHVK
>NZ_CP023011.2|WP_053765777.1|218658_219843_-|MFS-transporter
MDKNEKTTLTSSLILLLSITCGVVVANMYYIQPIGTKVAASLSVSTSAIGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAISLLAAFFAPSFTLFACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVASLFSWRMIYLFALVLVAILTGLLYWKMPRTQIKTTSSVSYLDSLKSLPYLVKTQRLLREASISGFFMFGTFSIFWSTLIFYISSPVYHWGTFEAGILAIFGLSGAVAAPIVGRLSDSYSERKIVGMGLAMQTLSFVALLVAGSHLVVLLVAIILLDVGNQFGQVANQTRVQGLGEAASNRNNTVFMFMYFIGGATGSLLGTTMWQQFGWLGVTLTGLAFQLCAYICQYIIFQKRS
>NZ_CP023011.2|WP_010720090.1|218021_218255_-|hypothetical-protein
METVARKIGNSVGAIFPKDISPKVGEIFTILKVGEAYILKPKKEDIFKNEKAWEGFRESITAEESEWDSMKLEGEEY
>NZ_CP023011.2|WP_080704604.1|217694_217997_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIWIDFDPSKGKDIRKRRPALVVSRDEFNKRTGFCLVCPITSTKRNFATYIEIKDPQKIVGEVATHQLRSVDYTTRNIEKIEQCDLLTWIEVVEVIGMFI
>NZ_CP023011.2|WP_053765776.1|215822_217352_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSLLTLTNITQQFGDKILYENVQLQVNAGEHLGLIGQNGAGKSTLIKIITGEILPDDGQVHWQKNIHRGYLDQYVAVDETLTIEEFLKTAYSDEFKKEALITQLYQEYSETMEEALLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLSTPLKKLSGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQSFEGAYIVISHDQEFLDKITTHIADIEFGKITKYTGHLKQALRQKEQNRESYLRQFHAQQKHIEKTEAYIRKYKAGSRSTMAKSRQKQLDKIERLTPPASTAKPIFDFPYSPIVTTLAVETTDLVIGYDRPLLSPINLTIRFGEKVAIRGFNGIGKSTLLKTLIGEIEQLAGEYHFPDNTAINYFSQDLIWEKPLETPLQYLGAQFPKATVKELRRQLAKSGLVNQLASEPLSTLSGGEQTKVKLAQLTMNQGNLLILDEPTNHIDHETKDSLQTGIKHFPGTVIIVSHEQEFYQDLVDRVIEIEG
>NZ_CP023011.2|WP_094940219.1|214691_215393_-|glucosamine-6-phosphate-deaminase
MEIIRVKNAEEGGKKAFEIIKKGMENGAKVLGLATGSTPITLYKEMTSSDLNFSDMTSVNLDEYVGLGGSDDQSYRHFMNSQLFDKKPFKESYVPDGKAADLEAACQEYDEILEQHPIDIQILGIGQNGHIGFNEPGAPFDGTTSVVDLTESTINANKRFFEKAEDVPTKAVSMGIGSILKGKEIVLLAYGENKADAIKGMIQGPMTTDLPASALQEHDNVIVIIDDAAGSKL
>NZ_CP023011.2|WP_010720150.1|223519_224209_-|50S-ribosomal-protein-L1
MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEVAYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQKIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGKVTYRVDKAGNIHVPIGKVSFDNEKLVENFATIHDVLVKAKPSAAKGQYMKNITVTTTFGPGIHVDQASF
>NZ_CP023011.2|WP_010720151.1|224312_224735_-|50S-ribosomal-protein-L11
MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIDKGSGEPNKTKVAKVSSDQVKEIAELKMEDLNAADIEAAMRMVEGTARSMGITVE
>NZ_CP023011.2|WP_010720152.1|225274_225943_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKELRYRSVFDIIGPVMIGPSSSHTAGAARIGKIVRSIFGEQPDSVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLQLAYEAGMEVLFVPKGEKAEHPNSVKLLLKKGKRKLSVTGISIGGGNIQISELNGFKISLSMGTPTFIIVHQDVPGMIAKVTNILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVDDTISKLTQLPKIDSVNYFD
>NZ_CP023011.2|WP_094940221.1|225956_226823_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFFSIEELVRQAENYPSVAELMIAVEMEMSGRPREQIIAIMEKNLSVMEQSIAEGNEGVTSVTGITGGDAQKLARYLKEADFLSGETILSAVRNAIAVNEVNAKMGLICATPTAGSAGVVPGVLMAVRDRLSLTHEQQIEFLFTAGAFGLVIANNASISGAEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAIAITLKNMMGLICDPVAGLVEVPCVKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPAIFKETAEGGLAVTPTAKRLTTELLNH
>NZ_CP023011.2|WP_094940222.1|227147_228188_+|hypothetical-protein
MKNKKLTWGCWWLVLSLLFTTILPPSITAFATEQTLQAARKEATVPFTLPNTLSPLEEPQKIAEIEKLTFQKGFSSLTSQRNVFDNLILNDYLDLMYGPAFLPLSTRFNLAPIAPIIQAVTLAEFTTPYLKPGAQETALSQAYRLTQKKLLRHTLVVFDEIIDHPENPTDLDEFSKMEMASWIALQNQFIDYLNVSPDLSGYQLIKTKEKLTFRPKTTDGQSLLVYLENSINNYYPGNIKIPPRIGSLQEITFVPSMWTDKQVNATFAFTAYDHEKQTYNNYSSNTINIAIETDFATFLNQMDTPETVLQFFLNHATVQIGAIPPNRCRYRQSDRKRHHWSNDQGT
>NZ_CP023011.2|WP_094940989.1|228624_229194_+|EndoU-domain-containing-protein
MRSLLTTVERGELIGAVEVEEAQAKTILAAEEEILLKGCPNKGIVEKIQPTKYFKRKTLNHLAGEVKPGKDGVPNLSGAHSRHPDFYRKESGIIYEPIGEVKKGMPYEAKVKYAGKYKEANSTVFPDDWDAEKIMKEVEQIISETTFNGTGNKPFSGKASNGLFEIQGHVNIKENGKITISTVYPLVKK
>NZ_CP023011.2|WP_094940223.1|229213_230194_-|hypothetical-protein
MRVFFPDPQRRPQKDIQEMTAKLTKQFQAIDERLTLEHFDDFVDYGPEVFPQLAPLYWDPRVPNHPMEHFVYYEYVLRLNGFPIYVITPYSEVIDKTYTRKGRDKDPFWSLMRRIDPEILSLIHEYQIQNLHYWRDLYSVTQFQAEINKINSRVSLIPEKTNNEARTLLFIDPKQRDPEFVRRTTEQMAQELAELDPHLSVVCHEDFIDFGPEDGLFLSECPFDPEEDDPDDPRAGLADTEYTVYYEDTILYASTPYSLGYGYHGDYFRGGIPSTEYLGLSQELTAEILKILHTFKIYNKYYWRHLYTPAEFQTEIRRYQKSWDLE
>NZ_CP023011.2|WP_095454061.1|230602_231487_-|alpha/beta-fold-hydrolase
MKNRRKSGIVGFLLMVSVLFISGCQTKETSQSSEAAKTVETTQVTEEKETQSTTPTLFFHGYSGTVNSFKGMIQRLESSESGKKELTLTVDVNGNVQAEGELSKEADNPMIQVLFVDNKNNEWNQTEWIKDCLSYLQQTYGINQVNLVGHSMGGVSGLRYLATYGQDQTLPKVDKFVAIAAPFNDFEENNGQSISDELANGPAIASSRYQDYQRLIGNVPTTTQILLIAGQVSETDLSDGTVPLSSALAVYALLKQHGNQVEEKVITGENVTHSMLHENKEVDALTRQFLWNID
>NZ_CP023011.2|WP_010720157.1|231730_232276_-|transcription-termination/antitermination-protein-NusG
MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVPEETEKEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPAPLLPEEVSHILRSIGMSLRQTDLEIEVGEVIKIIEGAFAGLEGQVTEVDEEKEKLKVNIDMFGRETSTELDFEQVDKID
>NZ_CP023011.2|WP_010720158.1|232375_232546_-|preprotein-translocase-subunit-SecE
MKFIKSVKDEMKQVTWPSGKQLRKDTLVVIETSIIFGVMFFVMDTAIQSLFAYLLK

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Crispr_ID: NZ_CP023011_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023011_2

614124-614264

Orphan

Consensus_repeat	Method
GCTTTTTGAACGCCGTTTA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP023011_2

>merge|NZ_CP023011|2|614124-614264|PILER-CR
GCTCTTTGAACGCCGTTTATCAAGAGGCTGTGAAAGAAGCGTTTAGCTCCGAGCAAATAAGAGAGGATTTTTTAAAATAGCTTCTCATATTTTTAAAAATCATCGCTTATTGTTGAGGAGCTGCTTCTTGAACGCCGTTTA

>NZ_CP023011|2|1|614124-614264|PILER-CR
GCTCTTTGAACGCCGTTTA	TCAAGAGGCTGTGAAAGAAGCGTTTAGCTCCGAGCAAATAAGAGAG
GATTTTTTAAAATAGCTTC	TCATATTTTTAAAAATCATCGCTTATTGTTGAGGAGCTGCTTCTTGAACG
CCGTTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023011.2\|WP_094940657.1\|610154_611111_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224005
NZ_CP023011.2\|WP_094940654.1\|621974_622580_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225370
NZ_CP023011.2\|WP_010720471.1\|614423_615506_-\|BMP-family-protein	unknown	unknown	gnl\|CDD\|224658
NZ_CP023011.2\|WP_010720465.1\|607130_607838_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP023011.2\|WP_094940655.1\|618114_619131_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380631
NZ_CP023011.2\|WP_034697755.1\|619299_619482_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_010720479.1\|622845_623769_+\|type-I-pantothenate-kinase	unknown	unknown	gnl\|CDD\|235466
NZ_CP023011.2\|WP_010720472.1\|615579_615978_-\|cytidine-deaminase	unknown	unknown	gnl\|CDD\|180142
NZ_CP023011.2\|WP_010736792.1\|607859_608678_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350160
NZ_CP023011.2\|WP_010720463.1\|605499_606081_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP023011.2\|WP_010736793.1\|604678_605362_+\|ribose-5-phosphate-isomerase-RpiA	unknown	unknown	gnl\|CDD\|234816
NZ_CP023011.2\|WP_094940656.1\|615995_616658_-\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
NZ_CP023011.2\|WP_010720469.1\|611110_612244_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226962
NZ_CP023011.2\|WP_010720470.1\|612236_613799_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226364
NZ_CP023011.2\|WP_010720467.1\|608890_610057_-\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NZ_CP023011.2\|WP_094940652.1\|625945_626266_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_002294318.1\|603956_604370_-\|30S-ribosomal-protein-S12	unknown	unknown	gnl\|CDD\|235355
NZ_CP023011.2\|WP_094940653.1\|623828_625394_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP023011.2\|WP_010720464.1\|606389_607076_+\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|223661
NZ_CP023011.2\|WP_034697695.1\|616672_617974_-\|pyrimidine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180387

Protein	Function_ID	Function_description	E-value
NZ_CP023011.2\|WP_094940657.1\|610154_611111_-\|ABC-transporter-permease	gnl\|CDD\|224005	COG1079, COG1079, Uncharacterized ABC-type transport system, permease component [General function prediction only].	1.01682e-107
NZ_CP023011.2\|WP_094940654.1\|621974_622580_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225370	COG2813, RsmC, 16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis].	2.42553e-75
NZ_CP023011.2\|WP_010720471.1\|614423_615506_-\|BMP-family-protein	gnl\|CDD\|224658	COG1744, Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only].	2.43851e-93
NZ_CP023011.2\|WP_010720465.1\|607130_607838_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	8.12098e-156
NZ_CP023011.2\|WP_094940655.1\|618114_619131_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|380631	cd19976, PBP1_DegA_Like, ligand-binding domain of putative DNA transcription regulators highly similar to that of the transcription regulator DegA. This group includes the ligand-binding domain of uncharacterized DNA transcription repressors highly similar to that of the transcription regulator DegA, which is involved in the control of degradation of Bacillus subtilis amidophosphoribosyltransferase (purF). This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.	7.23033e-109
NZ_CP023011.2\|WP_010720479.1\|622845_623769_+\|type-I-pantothenate-kinase	gnl\|CDD\|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	0
NZ_CP023011.2\|WP_010720472.1\|615579_615978_-\|cytidine-deaminase	gnl\|CDD\|180142	PRK05578, PRK05578, cytidine deaminase; Validated.	8.95667e-66
NZ_CP023011.2\|WP_010736792.1\|607859_608678_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|350160	cd09009, PNP-EcPNPII_like, purine nucleoside phosphorylases similar to human PNP and Escherichia coli PNP-II (XapA). Human PNP catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. Patients with PNP deficiency typically present with severe immunodeficiency, neurological dysfunction, and autoimmunity. Escherichia coli PNPII, product of the xapA/pndA gene, catalyzes the phosphorolysis of xanthosine, inosine and guanosine with equal efficiency and has been referred to as xanthosine phosphorylase and inosine-guanosine phosphorylase. E. coli PNPII is also capable of converting nicotinamide to nicotinamide riboside, and may be involved in the NAD+ salvage pathway. It is one of two purine nucleoside phosphorylases found in E. coli, which also contains PNPI, which displays a different substrate specificity and belongs to a different subgroup of the nucleoside phosphorylase-I (NP-I) family than PNPII. NP-I family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	7.94266e-168
NZ_CP023011.2\|WP_010720463.1\|605499_606081_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.32843e-32
NZ_CP023011.2\|WP_010736793.1\|604678_605362_+\|ribose-5-phosphate-isomerase-RpiA	gnl\|CDD\|234816	PRK00702, PRK00702, ribose-5-phosphate isomerase RpiA.	9.78272e-122
NZ_CP023011.2\|WP_094940656.1\|615995_616658_-\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	1.32328e-125
NZ_CP023011.2\|WP_010720469.1\|611110_612244_-\|ABC-transporter-permease	gnl\|CDD\|226962	COG4603, COG4603, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.4519e-106
NZ_CP023011.2\|WP_010720470.1\|612236_613799_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226364	COG3845, COG3845, ABC-type uncharacterized transport systems, ATPase components [General function prediction only].	0
NZ_CP023011.2\|WP_010720467.1\|608890_610057_-\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NZ_CP023011.2\|WP_002294318.1\|603956_604370_-\|30S-ribosomal-protein-S12	gnl\|CDD\|235355	PRK05163, rpsL, 30S ribosomal protein S12; Validated.	4.48259e-86
NZ_CP023011.2\|WP_094940653.1\|623828_625394_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP023011.2\|WP_010720464.1\|606389_607076_+\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|223661	COG0588, GpmA, Phosphoglycerate mutase 1 [Carbohydrate transport and metabolism].	6.38701e-142
NZ_CP023011.2\|WP_034697695.1\|616672_617974_-\|pyrimidine-nucleoside-phosphorylase	gnl\|CDD\|180387	PRK06078, PRK06078, pyrimidine-nucleoside phosphorylase; Reviewed.	0

>NZ_CP023011.2|WP_010720470.1|612236_613799_-|ABC-transporter-ATP-binding-protein
MVQENIVIEMRNITKQFGTFKANDNINLQVKAGEIHALLGENGAGKSTLMNVLSGLLEPTSGEILMHGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTENIVLGSEPSRAGVLDRRQAREEIQKLSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYRGADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRRGKGIGTVNVKDVSSQQLADMMVGRTVSFKTMKKESQPQEVVLSIENLVVKENRGLDAVKDLSLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGTIRLKDEDITNKKPRKITEAGVGHVPEDRHKYGLVLDMTLAENIALQNYYQKPYSRNGLLNYSLINEHARELIEEYDVRTTNELVPAKALSGGNQQKAIIAREIDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQRDKYKAVLLISFELEEILNVSDRIAVLHEGKIVGIVDPKETSENELGLLMAGYSLEEARKELEKVGGAHE
>NZ_CP023011.2|WP_010720469.1|611110_612244_-|ABC-transporter-permease
MNDRNEKIRNLLVPIFSVILGLVLGAILMAAFGYNPGQGYSSMLNASLGSQRSIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAFPDLPKVILLPTCVILGALAGALAAAIPGVLRAFFGTSEVIVTIMMNYILLYLSTFALHDIMPDTYRSSLDSSNLIGQNASLRLPWLTQMFGGSRVNAGLFLALIALVVVWLLMKKTTLGFEIRSVGLNPFASEYAGMSSKRTIVFSMMISGALAGLGGVVEGLGTYQNFFVQTTSLAIGFDGMAVSLLGSGSAIGILLSALLFSILKIGGLGMQTGAGIPFEIVNVSIALIIFFVGINFLIRFIMAKFFQGKKQEAIVETVESKPTNQSQEGGEL
>NZ_CP023011.2|WP_094940657.1|610154_611111_-|ABC-transporter-permease
MSTTELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGIMVMGAFSAVVFNLTMSPTLGDMTPWIAILVGGIVGVLFSLLHAVATISLRADHIISGTVINLMAPALGVFLIKTWYGKGQTDNISVNLGYFSFPGLSKIPVIGPIFFKNTFLPAYCAILIAILAWFIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGAVFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPVISSIPPVLLQIAPYLLTVIVLVAFLGKASGPKANGKNYIKSK
>NZ_CP023011.2|WP_010720467.1|608890_610057_-|phosphopentomutase
MFKRVHLIVMDSVGIGEAPDAEKFGDKGSDTLGHIAKEAGLTIPHLEQLGLGTIRPLEGVEAVKNHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFPNGFPDELLKQIEDFSGRKIVCNQPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAAHEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGNFTRTSNRHDYALDPFGHTVLDSLKEAGKDVIAVGKINDIFNGQGITEFVRTKSNMDGVDQLLNVMKKEFTGISFTNLVDFDALFGHRRDVVGYAHAIEDFDLRIPEILEAMAEDDLLMITADHGNDPTFPGTDHTREYVPLLVFSKKMQGQGSLPQGYYSDIAATIAENFDVPATENGESFLKLLK
>NZ_CP023011.2|WP_010736792.1|607859_608678_-|purine-nucleoside-phosphorylase
MTQLSEMLQETTQFILEKGVKEIDFGLILGSGLGELAEEIEEAIVIPYDQIPFFPTSTVVGHAGQLVYGTLSGKKVLAMQGRFHFYEGHSMQTVTYPVRVMAALKAHSVIVTNASGGVNESFVPGDLMLITDHINFTGQNPLIGPNEDEIGPRFPDMSEAYTLTYREVAKEAASQLDLTLKEGVYMGYSGPTYETPAEIRMSRTMGADAVGMSTVPEVIVAAHSGLKVLGISCITNLAAGMQANLNHEEVVETTQRVKQSFKALIKEVLVLL
>NZ_CP023011.2|WP_010720465.1|607130_607838_-|purine-nucleoside-phosphorylase
MSVHIEAKQGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRGMLGFTGTYKGERVSVQGTGMGMPSATIYAHELIHSYGVKKLIRVGTCGALSKDVHVRDLVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEISKDKGFTTHVGNVLSEDSFYKDDSTETFKLAELGVLGVEMEAAALYYLGAKYHVQTLAIMTVSDHLLTGEETTAEERQTTFNEMIEVGLETAIAD
>NZ_CP023011.2|WP_010720464.1|606389_607076_+|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIKEAGIEFDVAYTSVLTRAIKTCNLILEHSDQLWVPQIKSWRLNERHYGKLQGLNKKETAEKYGDDQVHIWRRSYDTLPPLMDESDEGSAANDRRYAMLDKRDIPGGENLKVTLERALPFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELNDDLTVAKKYYL
>NZ_CP023011.2|WP_010720463.1|605499_606081_+|recombinase-family-protein
MKIIGYARTTINDVDLTTQVEQLSNFGCQEIFHETYKSKDAVSNNICLEKVIKEMRQGDTLVICQLHRLGKSTRQLTELTQLFKDRGLHLVSIQEEIDTRTPMGKIYFQLMEGLAIMECSLIKERTLVGLDEARKKGKIGGRPKIDPKTIKKIRRLYYEKKETIQLISTKCGVSVGTCYKYINLPEKEIQQLS
>NZ_CP023011.2|WP_010736793.1|604678_605362_+|ribose-5-phosphate-isomerase-RpiA
MNLKQAAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEGLNITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISKAFQGIKGGGAALLFEKIVATYSKQVIWIVDESKLVEQLGQFPLPVEVIPYGAQQLMRIFDEKGYQPVLRQTETGQIVKTDSGHYIIDLHLEVINDPEALATYLDQLVGVVEHGLFLNMVSKVVVGSAQGVSIIDSPHQK
>NZ_CP023011.2|WP_002294318.1|603956_604370_-|30S-ribosomal-protein-S12
MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKRGVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA
>NZ_CP023011.2|WP_010720471.1|614423_615506_-|BMP-family-protein
MKKAKLFGLSAVALSAGLLLGACGSGSDSTDSTGGNSGSKTATAALITDTGGVDDRSFNQSAWEGLQAWGKDHDLSRGNDGFQYFQSANESDYIPNIDQALNAGFKTIFGIGYKLKPAIEEQAASNPETNFAIIDDVIDGKDNVVSATFKDNEASYLAGIAAAYTTETNTVGFIGGVKGEVIDRFDAGFKAGVDAGAKALNKEIKVLNQYAGDFSAPDKGRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYTLNGEKKNFTLTSTLKGVGTVVEDLAQKSADGDFPGGEHTVYGLKEDGVGITKGQLSEKAEKAVNEAKEKIISGDIKVPETPEK
>NZ_CP023011.2|WP_010720472.1|615579_615978_-|cytidine-deaminase
MTEVKQEWINIAVEALDKAYVPYSHFPVGACLVTESGKTYQGVNIENASFGLTNCAERTAFFKAVSEGEKEFTHLVVAGHTPEPISPCGACRQVMAEFCVPDMPVTLVGDNGVTKAMTVKELLPYAFTEKDL
>NZ_CP023011.2|WP_094940656.1|615995_616658_-|deoxyribose-phosphate-aldolase
MELNRMIDHTILKADASQEDVMRIIEEAKKYHFYSVCINPTWVALAKEQLKGEPVAVCTVIDFPLGANTAETKAFETTNAIENGADEVDMVINIGAMKSQQFDKVQKDIEAVVAAAKDRALVKVIIETALLNHEEIVKACELAKAAGADFVKTSTGFSTGGAKVEDVRLMRETVGPEMGVKASGGIHNEAEALAMIEAGATRIGTSAGVSIMSGSTGEGY
>NZ_CP023011.2|WP_034697695.1|616672_617974_-|pyrimidine-nucleoside-phosphorylase
MRMVDLIEKKRDGNELSTKEIEYIITKYTNGEIPDYQISALLMAIFYQDMTDREITDLTLAIAHSGDVIDLSPLDGIKVDKHSTGGVGDTTTLILAPLVASVGVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEAFIRIVNESKVAVIGQSGNLAPADKKLYALRDVTATVDSIPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLAKTMTSIGKLAHRQTVAVISDMSEPLGEAIGNSLEVVEAIETLNGNGPEDLLEMCYALGSQMVVLANQAATIEEARSLLQEALESGKALDKFKEMIRNQGGDDSIVDQPERLLTAKYVVELPAKSSGIVSKLVANELGIAAMMLGAGRKTKEDDIDHAVGLKLNKKIGDPVKEGESLLTIYSNTKEISSVQELLYQNIQISDSAEKPTLIHDIITE
>NZ_CP023011.2|WP_094940655.1|618114_619131_-|substrate-binding-domain-containing-protein
MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLNIVNEHHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHSQENEIKYLKELAHRSVDGILLATPNVLPDDYSLDSGFYKNMPIILIDRGLNTRDNGRLIVKEYEGAYQAVSLFIKNGHTKIGMLKETTGYYQLEERFNGYRHALKDYGIPFNGKYVEQGELTVQGGYEASKRLLKHKDLTAIFCGNDAMAIGCYQAIDELGKKIPDDISVIGFDGLKLSEYMIPQLTTVKQPSSDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESIKTLTKG
>NZ_CP023011.2|WP_034697755.1|619299_619482_-|hypothetical-protein
MVGAIEKRDSEHIAADHLVTQSQKSSLSEKVTSAINNRKDQSLVTQANEKTPMKEKNNDR
>NZ_CP023011.2|WP_094940654.1|621974_622580_-|class-I-SAM-dependent-methyltransferase
MTNHYYSQEPTTEHDFEQWSFELKGKNFQFVTDSGVFSRETVDFGSRVLIDTFNWEELPADGKILDVGCGYGPIGLAIAFASQRFVEMVDINSRAVELAQGNANRNGIKQVDIHQSNIYEAAHEETYAAIVSNPPIRAGKKVVHEILTEAYPRLKSGGTLTIVIQKKQGAPSAKSKMAETFGNAEIVHKEKGYYIIKSIKE
>NZ_CP023011.2|WP_010720479.1|622845_623769_+|type-I-pantothenate-kinase
MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQDVRDIYVPLAHLIYLYMKEFESLSLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARLLQTILSRTFKRRNVQLITTDGFLYPNETLKERGIMNRKGFPESYDMEMLIDFLNRVKSGQEEIKVPVYSHDIYNIIPGEYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVYVDADSSLIEKWYLDRFGALLDTAFQNPQNYYYQFAIGDRDDAFKMAQEVWKNVNLKNLNEYILPTRGRADIILHKTENHIIDSIFMRKY
>NZ_CP023011.2|WP_094940653.1|623828_625394_+|glutamine-hydrolyzing-GMP-synthase
MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRVSAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGKVEPAKNREYGKAQLEVTSDDTVLFNDTPKQQTVWMSHGDLVTQVPEGFEIVGTSKDCPIASIQDTKRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMNNFIDMQIEKIREQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEADQVMESLGGKFGLNIIKVDARKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGIAFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFQLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGEISEEKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWDVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE
>NZ_CP023011.2|WP_094940652.1|625945_626266_-|hypothetical-protein
MANEEIKQEEVLLAKNNLPIKTITKQDIDDLKMHLEQLTSWKQTLKLMHHFFDYDCLPLNKKKIIKEFHAQSKVFSIFYENFLFTTKVLEDKLEKLGKREKVKNNH

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Crispr_ID: NZ_CP023011_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023011_3

939102-939520

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	PILER-CR
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	CRT

5 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP023011_3

>merge|NZ_CP023011|3|939102-939520|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAACTTTTCATAGTTATTTAGCATTGCATTATCTGTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAACTAATGCCGATTTGATTTTACTTCCTTTATAGTTTTAGAGCTATGTTATTTTGAATGCTTCCAAAACAGTAACAGTGGTTGATGAAGTATCTTATACGTTTTAGAGCTATGTTGTTTTGAATGCTTCCAGAACCGGAATCTCGCGTTTTGAACTGCTAGTTTTGTTTTAGAGCTATGTTGTTTTGAATATTTCCAAAATGTAGAAGCGTTGTGCTTTACTCGATCGCTGTTTTAGTTTTGTGTTATTTTGAGTGCTGACCTCATCAACTATGATAAGAGGTAGCTTTAGAGTTATGTTGTTTTGAATGAATGAAGATG

>NZ_CP023011|3|2|939102-939335|PILER-CR
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	TTTTCATAGTTATTTAGCATTGCATTATCT
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	TAATGCCGATTTGATTTTACTTCCTTTATA
GTTTTAGAGCTATGTTATTTTGAATGCTTCCAAAAC	AGTAACAGTGGTTGATGAAGTATCTTATAC
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAGAAC

>NZ_CP023011|3|2|939102-939520|CRISPRCasFinder
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	TTTTCATAGTTATTTAGCATTGCATTATCT
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	TAATGCCGATTTGATTTTACTTCCTTTATA
GTTTTAGAGCTATGTTATTTTGAATGCTTCCAAAAC	AGTAACAGTGGTTGATGAAGTATCTTATAC
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAGAAC	CGGAATCTCGCGTTTTGAACTGCTAGTTTT
GTTTTAGAGCTATGTTGTTTTGAATATTTCCAAAAT	GTAGAAGCGTTGTGCTTTACTCGATCGCTGTTTTAGTTTTGTGTTATTTTGAGTGCTGACCTCATCAACTATGATAAGAGGTA
GCTTTAGAGTTATGTTGTTTTGAATGAATGAAGATG

>NZ_CP023011|3|1|939102-939401|CRT
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	TTTTCATAGTTATTTAGCATTGCATTATCT
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	TAATGCCGATTTGATTTTACTTCCTTTATA
GTTTTAGAGCTATGTTATTTTGAATGCTTCCAAAAC	AGTAACAGTGGTTGATGAAGTATCTTATAC
GTTTTAGAGCTATGTTGTTTTGAATGCTTCCAGAAC	CGGAATCTCGCGTTTTGAACTGCTAGTTTT
GTTTTAGAGCTATGTTGTTTTGAATATTTCCAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023011.2\|WP_010720996.1\|930585_932280_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NZ_CP023011.2\|WP_094940230.1\|952099_952699_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240029
NZ_CP023011.2\|WP_010720995.1\|932333_932462_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_010720987.1\|942683_944516_+\|tyrosine-decarboxylase	unknown	unknown	gnl\|CDD\|163523
NZ_CP023011.2\|WP_010720986.1\|944831_946262_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|163525
NZ_CP023011.2\|WP_010721000.1\|927083_927551_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|173926
NZ_CP023011.2\|WP_094940695.1\|937128_937995_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP023011.2\|WP_094940696.1\|937991_938336_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP023011.2\|WP_088745579.1\|946278_947598_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP023011.2\|WP_094941012.1\|929612_930458_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_094940228.1\|947707_950251_+\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP023011.2\|WP_094940697.1\|938325_938985_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP023011.2\|WP_094940226.1\|939802_940174_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NZ_CP023011.2\|WP_010720989.1\|940163_940523_+\|DUF1622-domain-containing-protein	unknown	unknown	gnl\|CDD\|377914
NZ_CP023011.2\|WP_094940691.1\|927847_928162_-\|YrhK-family-protein	unknown	unknown	gnl\|CDD\|372928
NZ_CP023011.2\|WP_010720983.1\|950388_951843_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375760
NZ_CP023011.2\|WP_095454139.1\|933136_937147_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP023011.2\|WP_053766210.1\|952799_953252_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP023011.2\|WP_095454138.1\|928189_929323_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176243
NZ_CP023011.2\|WP_094940227.1\|940757_942188_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|311953

Protein	Function_ID	Function_description	E-value
NZ_CP023011.2\|WP_010720996.1\|930585_932280_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NZ_CP023011.2\|WP_094940230.1\|952099_952699_+\|NUDIX-hydrolase	gnl\|CDD\|240029	cd04672, Nudix_Hydrolase_14, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	8.49112e-62
NZ_CP023011.2\|WP_010720987.1\|942683_944516_+\|tyrosine-decarboxylase	gnl\|CDD\|163523	TIGR03811, tyrosine_decarboxylase, tyrosine decarboxylase, Enterococcus type. This model represents tyrosine decarboxylases in the family of the Enterococcus faecalis enzyme Tdc. These enzymes often are encoded next to tyrosine/tyramine antiporter, together comprising a system in which tyrosine decarboxylation can protect against exposure to acid conditions. This clade differs from the archaeal tyrosine decarboxylases associated with methanofuran biosynthesis. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP023011.2\|WP_010720986.1\|944831_946262_+\|amino-acid-permease	gnl\|CDD\|163525	TIGR03813, put_Glu_GABA_T, putative glutamate/gamma-aminobutyrate antiporter. Members of this protein family are putative putative glutamate/gamma-aminobutyrate antiporters. Each member of the seed alignment is found adjacent to a glutamate decarboxylase, which converts glutamate (Glu) to gamma-aminobutyrate (GABA). However, the majority belong to genome contexts with a glutaminase (converts Gln to Glu) as well as the decarboxylase that converts Glu to GABA. The specificity of the transporter remains uncertain.	3.77268e-52
NZ_CP023011.2\|WP_010721000.1\|927083_927551_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	6.49402e-07
NZ_CP023011.2\|WP_010720989.1\|940163_940523_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	8.19495e-21
NZ_CP023011.2\|WP_094940696.1\|937991_938336_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.82613e-43
NZ_CP023011.2\|WP_088745579.1\|946278_947598_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	4.77977e-123
NZ_CP023011.2\|WP_094940228.1\|947707_950251_+\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP023011.2\|WP_094940697.1\|938325_938985_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.72434e-113
NZ_CP023011.2\|WP_094940226.1\|939802_940174_+\|DUF1622-domain-containing-protein	gnl\|CDD\|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	2.07485e-21
NZ_CP023011.2\|WP_094940695.1\|937128_937995_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.25183e-122
NZ_CP023011.2\|WP_094940691.1\|927847_928162_-\|YrhK-family-protein	gnl\|CDD\|372928	pfam14145, YrhK, YrhK-like protein. The YrhK-like protein family includes the B. subtilis YrhK protein, which is functionally uncharacterized. Its expression is under the control of the motility sigma factor sigma-D. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 60 amino acids in length.	1.3896e-14
NZ_CP023011.2\|WP_010720983.1\|950388_951843_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375760	pfam18333, ssDNA_DBD, Non-canonical single-stranded DNA-binding domain. This domain is found in ThermoDBP, a non-canonical single-stranded DNA-binding protein in Thermoproteales. Single-stranded DNA-binding proteins are needed for DNA metabolism, sequestering and protecting transiently formed ssDNA during DNA replication and recombination, detecting DNA damage and recruiting repair proteins. The outer edge of the ssDNA-binding cleft, formed by this domain, has a strongly positive electrostatic surface potential because of the conserved basic residues R49, K54, R65, R80, R86, R90, K97, and R112.	1.8487e-16
NZ_CP023011.2\|WP_095454139.1\|933136_937147_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	0
NZ_CP023011.2\|WP_053766210.1\|952799_953252_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.18848e-18
NZ_CP023011.2\|WP_095454138.1\|928189_929323_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176243	cd08283, FDH_like_1, Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	2.37454e-173
NZ_CP023011.2\|WP_094940227.1\|940757_942188_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|311953	pfam08280, HTH_Mga, M protein trans-acting positive regulator (MGA) HTH domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions.	0.0017752

>NZ_CP023011.2|WP_094940697.1|938325_938985_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLEQPISFEKALIFVIEDVEVFSKVVHGVYQYGENSMLKFFNDKLQLLKPSELMVVTDILSFDSQAPTTLKLIYADLEQQLNENIELKSRIDQLTTRVQEWISEELLEHELDLVCEEMSMVELFKALKIRITTQPESIFQKIMEILQIYKYLVKKKCLVFINVGAYLTIIEMAELQEYISLCHMPVLFIEPRKIKGLKPTVLDQDYFLCEEMW
>NZ_CP023011.2|WP_094940696.1|937991_938336_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMLLMFDLPTETSDDRKVYRRFRNFLLSEGFIMHQFSVYSKLLLNGTANQAMLGRLKAHHPKKGLVTLLTVTEKQFSRMVYLCGEKDLSPANSDERVIFLGEDVEDEP
>NZ_CP023011.2|WP_094940695.1|937128_937995_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVINTHSKLTYANNHLVFKNAQQTEKIHLSEIDILILETTDITITTMLLKRLTDEKILVIFCDDKRLPSSQLLSYYGRHDSSLQLSKQIQWESDLKGVVWTTIIAQKIHNQCRFLQENDFVEKASALSKLSEELETFDPTNREGHAARIYFQTLFGNQFTREESNEINAGLDYGYTLLMSLFAREIVKNGCMTQFGLKHANQFNDFNLASDLMEPFRPLVDQIVYTYRDQPFPIIKRRLFDLFSQKYLYGKKEMFLTNIVTDYTNKTIKTLNNEGKGVPYFGI
>NZ_CP023011.2|WP_095454139.1|933136_937147_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTKDYTIGLDIGTNSVGWAVLTDDYQLMKRKMSVHGNTEKKKIKKNFWGARLFDEGQTAEFRRTKRTNRRRLARRKYRLSKLQDLFAEELCKQDDCFFVRLEESFLVPEEKQYKPASIFPTLEEEKEYYQKYPTIYHLRQKLVDSTEKEDLRLVYLALAHLLKYRGHFLFEGDLDTENTSIEESFRVFLEQYGKQSDQPLIVHQPVLTILTDKLSKTKKVEEILKYYPTEKINSFFAQCLKLIVGNQANFKRIFDLEAEVKLQFSKETYEEDLESLLEKIGDEYLDIFLQAKKVHDAILLSEIISSTVKHTQAKLSSGMVERYERHKADLAKFKQFVKENVPQKATAFFKDTTKNGYAGYIKGKTTQEEFYKFVKKELSGIVGSEPFLEKIDQETFLLKQRTYTNGVIPHQVHLTELKAIIDQQKQHYPFLEEAGPKIIALFKFRIPYYVGPLAKEQEASSFAWIERKTAEKINLWNFSEVVDIEKSAMRFIQRMTKQDTYLPTEKVLPKNSLLYQKYMIFNELTKVSYKDERGVKQYFSGDEKQQIFKQLFQKERGKITVKKLQNFLYTHYHIENAQIFGIEKAFNASYSTYHDFMKLAKTNQKAMQEWLEQPEMEPIFEDIVKILTIFEDRQMIKHQLSKYQEVFGEKLLKEFARKHYTGWGRFSAKLIHGIRDRKTNKTILDYLINDDDVPANRNRNLMQLINDEHLSFKEEIAKATVFSKHKSLVDVIQDLLGSPAIKKGIWQSLKIVEELIAIIGYKPKNIVIEMARENQKTHRTKPRLKALENGLKQIGSTLLKEQPTDNKALQKERLYLYYLQNGRDMYTGEPLEIENLHQYEVDHIIPRSFIVDNSIDNKVLVARKQNQKKRDDVPNKQIVNEQRIFWNQLKEAKLISPKKYAYLTKIELTPEDKARFIQRQLVETRQITKHVANILHQSFNQEEEGTDCDGVQIITLKATLTSQFRQTFGLYKVREINPHHHAHDAYLNGFIANVLLKRYPKLAPEFVYGKYVKYSLARENKATAKKEFYSNILNFLESDEPFCDENGEIYWEKSHHLPRIKKVLSSHQVNVVKKVEQQKGGFYKETVNSKEKPDKLIERKNNWDVTKYGGFGSPVIAYAIAFVYVKGKTQKKTRAIEGITIMEQAAFEKDPTTFLKDKGFPHVTEFIKLPKYTLFEFDNGRRRFLASHKESQKGNPFILSNQLVTLLYHAQHYDKITYQESFDYVNTHLSDFSAILTEVLAFAEKYTLADKNIERIQELYEENKYGEISMIAQSFLQLLQFNAIGAPADFKFFGVTIPRKRYTSLTEIWDATIIYQSVTGLYETRIRMGDLWAGEQ
>NZ_CP023011.2|WP_010720995.1|932333_932462_-|hypothetical-protein
MSKKWIKLGIGLGILTLGAVYLGKKTGLLEDDRHLYDEFESI
>NZ_CP023011.2|WP_010720996.1|930585_932280_-|oleate-hydratase
MRKSKAIMIGAGIANMAAAVYLIQEGNWRGDQITFYSLDDHGSNDGAPTDTVVDEYWNKNHPLENKKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTAAEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRLLLTKLIAMPDSEEEKLDNVTIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVNRTRYNQYESIMLPLINYLKDQGCQIILNRRVVDWEFKETPMQDEITVTGLKMINTLTNEEEHVVVDGDTGVLFTNGSITDSATLGDYDTPAVENMDYGAASSLWKKASERFYNLGNPDKFFADRDASEWVSFTLTTKDHLLLNEITRITTQVPGNALNSFISTTPITPLGQKDVNMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMTGKEMLEELIGQLSKVDPGPENIRTKETEIFDSVVNNIPVYMPYASALFNNRAKSDRPKVIPQHSTNLAFTGEFVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLMRAAKKMFE
>NZ_CP023011.2|WP_094941012.1|929612_930458_+|hypothetical-protein
MVTFACSVTLFVIISVGIIQVTFFDQAYLLGQIEKTKYSELILAEAAQNFRKENTEESEFSEVVATALSPSFVEEALRPFIQHTYEETNYELRDSNEVSEKIAQAVATIATKKQLTIDKEEKNKIETMIFIYMYHFQSALGDRYLTIFIENIVSARKIVVPLFYICLGLLAFWLVYLYRVINKTPFSFLRYGMFILGTTGSMFCVLAGLLYIQDVLHNIAFQSQATLQLMTHYVQDLLMYPAIIGGILLSCAVLFGGGSKLLQKRQSKKWLKTGSSALKKA
>NZ_CP023011.2|WP_095454138.1|928189_929323_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAVTWQGNQKMEIRNVDDPKIVEPTDAIIRITATAICGSDLHLYHHGEAVLEKGYVVGHEPMGIVEEVGPAVKKLKKGQRVVIPFNISCGHCHFCTHEMESQCDRSNPDQLYGGLFGFGRLNGNHWGGQAEYLRVPFADSTSFIVPDNDLADEKVLFLSDILPTAYWSVQNANVKKGDTVVVLGSGPVGLFAQKFAAMAGAERVIAVDPVQHRIDKAARYNHVETYLLEDTQSAGKELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGTISPIQMAAQAVKKFGTVQITGVYMTPASSYPLQEFFMRDITVKHGQAPIVHLMPKIYEMIAAGLFDPTQIITHAMPLADAVRAYEIFDKKEDKNIKVVLKP
>NZ_CP023011.2|WP_094940691.1|927847_928162_-|YrhK-family-protein
MPEIKRKSHEIDIGKEEDIEIAGQRFRLYFQNRYTLLSLAVDLLTGIFYIFGSVALLTDIPDRYSTYCYLVGAIFLTARPILKIVRNVFIYDEKKKTKKERKKE
>NZ_CP023011.2|WP_010721000.1|927083_927551_+|GNAT-family-N-acetyltransferase
MKGYELVKIRERPEWLEQAAQWFTSKWHLPLSFYQESMEDSLQSSNAVPQWYIVVTSEQKIIAGAGVIANDFHDRPDLTPNVCALFVEKEYRNQGIAKEILSFIREDMGALGISQLYVATDHTGFYERYEWEYLTTVQDNEGIPVYLYQLAIFTT
>NZ_CP023011.2|WP_094940226.1|939802_940174_+|DUF1622-domain-containing-protein
MFDTNLTTYLDWLIAILNIASIIILLVGIFLVLKNLFDWHPLKKDYEQRNFRNAEVRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLAVIIIIRTIISYFLNLETQDKKQVKVGTHNGN
>NZ_CP023011.2|WP_010720989.1|940163_940523_+|DUF1622-domain-containing-protein
MEINLIEKLAPYLELLVIVLDVFAILIILWGAWLAIKDFLYFSFTERRIKAERINQNNAIKKMLGGYILLSLEVLISAGIIESIIKPTLEDVFQLAALVVIRTIISFFLNKEIGSDARQ
>NZ_CP023011.2|WP_094940227.1|940757_942188_-|helix-turn-helix-domain-containing-protein
MFEDYLEKNILRQLFLCGQFYHKKEIDLDELSHLLQVCKTTLLNDIKAIRTELKDEIIYSQREKDTCSLYFDPTIPRFRLIQKLARPSLFLKTCQLYLENEPNYLQLTEIEYISVSKAYSLKKQVLAYFEDCDIQIQHHSPRFTEIERRLLLLNVTYRTGTLKIPTLPADYFLAIDEFIESVTFNSRRIYDKDNREILRIGLLISYLSQKRHPLSIEQDFIAELQKRPIYQYVMDAWHTTKLKYYYQENEVYFALILFNLSDYGFNSYQAIEEDFCHLHQVFIEDSQSIKQLITQFESYFNRKFIGNRAFERALIRLMRTAWDNYQLFVPEKFYLLSPEQQSLLAEIQPLFNQWLAQLPYRLRLKINCLDAFVIELSGILRINKTKLNVRIVTNSDVKYLIYREALESVTTFDMEVDPVVYQHLDEAIKSAAQQENTRILCEKTLYTPEAEQFPTIVPVSVDTIEKSIVWAVQAVR
>NZ_CP023011.2|WP_010720987.1|942683_944516_+|tyrosine-decarboxylase
MKDMDIKAVFIGDKSENGAFYKMQLNKMVDEHLGWRENYLPGDVAAISEADKQAPRYIATREHMVEVLDEVSQRMRAGSIPWHSAGRYWGQMNAETLMPALLAYNFAMLWNPNNVALESSMATSQMEAEVGQDFADLFNMTGGWGHITADGSIANLEGLWYARCIKSIPLAVKEVYPEKVKDKTDWELLNLSVEEILEMVGTFSDEELDAVKAASSRSGKHLQELGKWLVPQTKHYSWMKALDICGIGLDQMIAIPVQEDYRMDVAILEKTIRELAAQKIPVLGVVAVVGTTEEGQVDSVDKIVELREKLYKEGIYFYLHVDAAYGGYARALFLNEAGEFVPYESLPDFFEEHHVFNYDVSIDQSVYDGFKAISEADSVTIDPHKMGYVPYAAGGIVIKHKEMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLPLNITGYGQLIGASIEAAQRFRAFLEQLSFTIKGKTIEVYPLNHPDFNMVNWVFKVKGCTDLKTINELNEKMFNRSSYMEGDVYSEHFITSHTTFMKEEYGDSPLPFIERIGLSKEEWQKEQKVTLLRAAIMTPYLNDDKIFEFYTQGITKAMEKTLNEIL
>NZ_CP023011.2|WP_010720986.1|944831_946262_+|amino-acid-permease
MTDSKTSQITTLTFIGMTCALVASVRNIPDVAATGWTMLFYMLVAVLFYAFPISLISGEFAGMFPQKGGPELWVSNSLGRKWGFVVSWLLWVQMFPGMVMVASALAPLLGNMIDNVPLGLNSKFTLIVILVVYWIITLLNLKFDMAKIGGKIGVWLGLYIPLAIMLLLGIFSWIKVGIQPHATLGHFSWAKLIPDAETAKSFVYFAPIMFIFTGIEMSSVYITRLKNPVKTYTKGIFAALIFLFFVNTLNALVVANVVPKGQMELNNIAQSISIYCQILGLPHIIVNIFSLLVFVGVAVQLSAWASGPAKTVTASARKGAYPPKFNFWKTNQFDVSKSVILTQSTIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAILKLRKAKPELARPFRIGKKGGKGDLGAWIVVLVLFAAIGCSVGLTMQAGTLINFIAVTVISLILFIAPLCIDKIRKPSWEQEVQQKLNQE
>NZ_CP023011.2|WP_088745579.1|946278_947598_+|amino-acid-permease
MERTTMKKTLTNRNIQMIALGGAIGTGLFLGSAKAIKLAGPAVLLTYFVCGLAIYGLMYAMGELFLSNNEFQSIGDFIQYYLGERWAFLVNWTYWLCWMGAGLTELTAIGLYIRFWLPALSPLISGIFALIALVIINVVAVRWFGELESLFSTIKIFGILLFILLGIGVCFLYFKSPRIGVRENFDQLQTIFPFGLTGLVAAFPMVLFSFAGVEMIGLTVGETADPQKNLKKAIQCLPARILFFYIGTIVAILLVVPWQSLDLKESPLVTMLQFIHCSKGAGVINLIILVASLSSTNSAIYSTSRILYNTAKEKNLSKWFLTLSSRGVPLHGILFTGGMFLLGLCLHFFVSDSRILFQLLAGMTTISFLFVWSAILFAHLKLTNSQLKKWKDRLILCFFGLVGISLFFEPTTRVIPVVSVVWFGALNLIYQRIRQTAPK
>NZ_CP023011.2|WP_094940228.1|947707_950251_+|HAD-IC-family-P-type-ATPase
MVWYKETAQEVMKTLKTTPDGLNQDERISRLKENGYNHIEVKKKVSPLRKFLKHLTELLMIILLVASLLKFFTGEVIEGSIILAVVLVNSFVGYWQERKAEEALNGLEKLLGQNAVIFTEGIKELVPAKELVPGDLLALKAGDVVPADVRLIEVHDFMVEEAALTGESEAVEKTSERLTTTVSTGDQKNLAFSGTLVQTGTAIGVVIETGDTTEIGKINQALQSVQQQTTPLVKKINQLNKQIFRGILFLSLFLLFFTTFRYGLEMNFLFSTIIALIVSMIPEGLPAVLTMILSLGVNEMAKEQAIIKGLPSVETLGSMTVICSDKTGTLTKNEMSVVETVTDQEETMLAIMKNCQEIQTKANQNVAELTGNPTELALLRYTAKASLPLEPVKGKIPFSSSYKYMATMHDKQEHAIVYVKGAPEVLLAKANLTPKQVGKWQEEAMKLAQKGQRVLGFAYKTLAPDQELGHDQLNELTFVGIAGIIDPPKESAIRAVKECQNAGISVKMITGDHKDTAQAIAEQIGLKHTKNVLEGIDIDRLSDEELAKQVKSVDVFARTTPEHKLRIVDALQKNEEIVGMTGDGVNDAPALKRADVGIAMGIKGSEVSKQAADMVLGDDNFHTIAKAVKEGRRILDNLQKTINFFLPTALAQGLVIIWALLVNQPLPLTPVQILWVNMVTTITLSYALGFEKAGKDTMSRSPRDPKQGILTRYSVFRIFYVSLLIMIPAYLLAMSFEGQALQQTMLLQNIVAAQAVYMINCRELLDPSLNRSLFENKALFLSLGMLVLLQAGVIYLPIAQQLIGTTSLSLTEQLPILLNILILFVIVEIEKRISKMIAKKRNAELPT
>NZ_CP023011.2|WP_010720983.1|950388_951843_-|helix-turn-helix-domain-containing-protein
MYSLMKKIITEKDIKRQVSLVELLLNHSQITVNELAEAVNTTERTIFSDLQTIKTQLPKGWLINSDQSGIQLKNEQNLLTNELWEIFLTQSISVQLLKELLTIKEVATPTFLARNGLSYETLNRHVKKLNQQLVVYELQIEQNRHRLSFSGEEETIRLFYHRLLMPFTHNNYFFEDYSIHESHYFRFLKRLRQAELAVDTEEVFGICWFFINTIRIKAGCRIPTSLFSTQDQLFLLYAPELEKLYRTEGVYLKDKEAAFAFSCFLDSWNYNNSYPPMILDILHRHPAETNIREFVNRLSESLAIKELEQTNLPENLILLLLKYYESPLLIEQTTKQYHYYLKEYEQEYPELYPHKFALLQQVKESTSMVKKVTNETYFFYLLSLLIQQTLLAVQPYQATIYFIFQGEPSWKAFLQQELNAYLGKRVILEPIELSQLSDITIKKNDLLVSNIPIDTPPMPVIYLSTIPTKNELDRLSDLSLRSYL
>NZ_CP023011.2|WP_094940230.1|952099_952699_+|NUDIX-hydrolase
METRLNDYRRLLAIAQAGLLYGKDVFDKERYEELQEISLKLLSEVGLETKEEWTSLIEAHEGYPTPKVDVRAWIKQDEKILLIEDTKTQEWSLPGGFAEVGLSPKENIRKEVKEETGLEVEVGQLLAIFDTNLRADIPQAFQYYKIVFSCAILSGTFVANHETSNMKFFHLNDLPKLSLKRTTKEQLLILEKATLPYCD
>NZ_CP023011.2|WP_053766210.1|952799_953252_+|MarR-family-transcriptional-regulator
MDEIIREIGAIARALDSISNIEFQEVDLTRGQYLYLVRICEHPGIIQEKLAEMINVDRTTTARAVKKLIAKDLIKSMPDKNNKKIKKLYPTDRGKKVYPFILREHHYSNQVAVKGLSQQEVLQLHTLLQKVRKNVSEDWHYIKKGNKRIY

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Crispr_ID: NZ_CP023011_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023011_4

2112971-2113205

Orphan

II-A,II-B

Consensus_repeat	Method
CATTCAAAACAACATAGCTCTAAAACCT	CRT
GTTTTGGAAGCATTCAAAACAACATAGCTCTAAAAC	CRISPRCasFinder
AGGTTTTAGAGCTATGTTGTTTTGAATGCTTCCAAAAC	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP023011_4

>merge|NZ_CP023011|4|2112971-2113205|CRT,CRISPRCasFinder,PILER-CR
AATTCAAAACCAACTCTGTGCAAGCTCTTCGCCTTAAAAACGACAAGCGAAGTACAGCAACTATTAGTTCAGAAACATTCAAAACAACATAGCTCTAAAACCTACCAGAAGTACCAAACATTAAGCCACTCGTTTTGGAAGCATTCAAAACAACATAGCTCTAAAACTAAATGAGAGCAACGGCAATTTCCATTTGAGTTTTGGAAGCATTCAAAACAACATAGCTCTAAAACCT

>NZ_CP023011|4|2|2112971-2113205|CRT
AATTCAAAACCAACTCTGTGCAAGCTCT	TCGCCTTAAAAACGACAAGCGAAGTACAGCAACTATTAGTTCAGAAA
CATTCAAAACAACATAGCTCTAAAACCT	ACCAGAAGTACCAAACATTAAGCCACTCGTTTTGGAAG
CATTCAAAACAACATAGCTCTAAAACTA	AATGAGAGCAACGGCAATTTCCATTTGAGTTTTGGAAG
CATTCAAAACAACATAGCTCTAAAACCT

>NZ_CP023011|4|3|2113036-2113203|CRISPRCasFinder
AGTTCAGAAACATTCAAAACAACATAGCTCTAAAAC	CTACCAGAAGTACCAAACATTAAGCCACTC
GTTTTGGAAGCATTCAAAACAACATAGCTCTAAAAC	TAAATGAGAGCAACGGCAATTTCCATTTGA
GTTTTGGAAGCATTCAAAACAACATAGCTCTAAAAC

>NZ_CP023011|4|3|2113042-2113205|PILER-CR
GAAACATTCAAAACAACATAGCTCTAAAACCTACCAGA	AGTACCAAACATTAAGCCACTCGTTTTG
GAAGCATTCAAAACAACATAGCTCTAAAACTAAATGAG	AGCAACGGCAATTTCCATTTGAGTTTTG
GAAGCATTCAAAACAACATAGCTCTAAAACCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023011.2\|WP_094940265.1\|2105638_2106310_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224922
NZ_CP023011.2\|WP_010737540.1\|2114731_2115661_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235982
NZ_CP023011.2\|WP_010737538.1\|2116612_2119798_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_CP023011.2\|WP_094940264.1\|2106306_2107029_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213225
NZ_CP023011.2\|WP_010719216.1\|2123120_2124404_-\|uracil-transporter	unknown	unknown	gnl\|CDD\|236744
NZ_CP023011.2\|WP_094940267.1\|2103744_2104551_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_053766051.1\|2110512_2111421_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP023011.2\|WP_010719217.1\|2124417_2124957_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	unknown	unknown	gnl\|CDD\|235365
NZ_CP023011.2\|WP_053766057.1\|2120882_2122163_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236479
NZ_CP023011.2\|WP_095454257.1\|2108140_2109373_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_010719215.1\|2122181_2123108_-\|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234849
NZ_CP023011.2\|WP_095454258.1\|2112153_2112795_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP023011.2\|WP_095454260.1\|2119800_2120877_-\|carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP023011.2\|WP_010719204.1\|2109616_2109790_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023011.2\|WP_010719209.1\|2114018_2114735_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NZ_CP023011.2\|WP_094940263.1\|2115657_2116434_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	unknown	unknown	gnl\|CDD\|99814
NZ_CP023011.2\|WP_094940268.1\|2103236_2103572_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP023011.2\|WP_094940266.1\|2104814_2105627_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270318
NZ_CP023011.2\|WP_053766052.1\|2111417_2112122_-\|carbonic-anhydrase-family-protein	unknown	unknown	gnl\|CDD\|239398
NZ_CP023011.2\|WP_192574426.1\|2113386_2114037_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771

Protein	Function_ID	Function_description	E-value
NZ_CP023011.2\|WP_094940265.1\|2105638_2106310_-\|ABC-transporter-permease-subunit	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	3.31534e-62
NZ_CP023011.2\|WP_010737540.1\|2114731_2115661_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|235982	PRK07259, PRK07259, dihydroorotate dehydrogenase.	0
NZ_CP023011.2\|WP_094940264.1\|2106306_2107029_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213225	cd03258, ABC_MetN_methionine_transporter, ATP-binding cassette domain of methionine transporter. MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	7.47511e-107
NZ_CP023011.2\|WP_010719209.1\|2114018_2114735_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	1.26654e-127
NZ_CP023011.2\|WP_053766057.1\|2120882_2122163_-\|dihydroorotase	gnl\|CDD\|236479	PRK09357, pyrC, dihydroorotase; Validated.	0
NZ_CP023011.2\|WP_010719216.1\|2123120_2124404_-\|uracil-transporter	gnl\|CDD\|236744	PRK10720, PRK10720, uracil transporter; Provisional.	6.38797e-148
NZ_CP023011.2\|WP_010719215.1\|2122181_2123108_-\|aspartate-carbamoyltransferase-catalytic-subunit	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	1.32084e-168
NZ_CP023011.2\|WP_095454258.1\|2112153_2112795_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	1.59242e-55
NZ_CP023011.2\|WP_095454260.1\|2119800_2120877_-\|carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP023011.2\|WP_010737538.1\|2116612_2119798_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP023011.2\|WP_053766051.1\|2110512_2111421_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	8.86162e-42
NZ_CP023011.2\|WP_010719217.1\|2124417_2124957_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	gnl\|CDD\|235365	PRK05205, PRK05205, bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR.	2.34565e-97
NZ_CP023011.2\|WP_094940263.1\|2115657_2116434_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	gnl\|CDD\|99814	cd06218, DHOD_e_trans, FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+. In L. lactis, DHOD B (encoded by pyrDa) is co-expressed with pyrK and both gene products are required for full activity, as well as 3 cofactors: FMN, FAD, and an [2Fe-2S] cluster.	2.71919e-105
NZ_CP023011.2\|WP_094940268.1\|2103236_2103572_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.68291e-23
NZ_CP023011.2\|WP_094940266.1\|2104814_2105627_-\|hypothetical-protein	gnl\|CDD\|270318	cd13600, PBP2_lipoprotein_like_1, Putative periplasmic-binding component of ABC-type methionine uptake transporter system-like; the type 2 periplasmic binding protein fold. This subgroup shares significant sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	1.51098e-96
NZ_CP023011.2\|WP_053766052.1\|2111417_2112122_-\|carbonic-anhydrase-family-protein	gnl\|CDD\|239398	cd03124, alpha_CA_prokaryotic_like, Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. Most alpha CAs are monomeric enzymes. The zinc ion is complexed by three histidines. This sub-family includes bacterial carbonic anhydrase alpha, as well as plant enzymes such as tobacco nectarin III and yam dioscorin and, carbonic anhydrases from molluscs, such as nacrein, which are part of the organic matrix layer in shells. Other members of this family may be involved in maintaining pH balance, in facilitating transport of carbon dioxide or carbonic acid, or in sensing carbon dioxide levels in the environment. Dioscorin is the major storage protein of yam tubers and may play a role as an antioxidant. Tobacco Nectarin may play a role in the maintenace of pH and oxidative balance in nectar. Mollusc nacrein may participate in calcium carbonate crystal formation of the nacreous layer. This subfamily also includes three alpha carbonic anhydrases from Chlamydomonas reinhardtii (CAH 1-3). CAHs1-2 are localized in the periplasmic space. CAH1 faciliates the movement of carbon dioxide across the plasma membrane when the medium is alkaline. CAH3 is localized to the thylakoid lumen and provides CO2 to Rubisco.	8.43067e-65
NZ_CP023011.2\|WP_192574426.1\|2113386_2114037_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	4.20926e-83

>NZ_CP023011.2|WP_095454258.1|2112153_2112795_-|HD-domain-containing-protein
MGLNEFILGLNNLEKITRAPGFFKFTEHTVAAHSYRVASIAQVLGDIEEVHGQAIDWKLLYEKALNHDYTERFIGDIKTPVKYANKELRGMLQTVEEKMTDEFINQEIPEEFQEVYRRRLFEGKDDTVEGELLAISDKVDLLYESFEEIIKNNPEKVYKEMFIEAVTTIKGFEHRPFVKYFFNEIFPELLNQEFYGKEDFLATVSTIVKNSQQ
>NZ_CP023011.2|WP_053766052.1|2111417_2112122_-|carbonic-anhydrase-family-protein
MKKNMDVEWGYTGERGPEHWAELCDWFAKGAAFELQSPIPLTTCEPAKDQSDTIAFHYQKQRFTDKEFKNTIHLVPYDQLSYVEFKGQKYYLTDIHFHMPSEHLINGNQEDIEFHFVHMNAKKENLVVGVMFQLTTDEGWLYDRDNGDSWDVEKHEHWTNPLVLFPEQKSHYHYVGSLTTPPTSGPIQWFVMDQVQKLNKDFLIPFKGQYAQPNNRPLQPLKNRPISYFVRDHQ
>NZ_CP023011.2|WP_053766051.1|2110512_2111421_-|LysR-family-transcriptional-regulator
MNFQQLKYVIAVANNGSFREAAKKLYVAQPSLSAGIKELETELGITLFTRTNRGAYLTEEGQEFLKRAERILLQLESLENYYLTNEKRESFSIASQHYDFLGPLTAKLISSFKSEIKQFRIIETTTANVIEEVKDQHSEIGILYMNEHNQAGIKRYLEQGELVAHSLGEFQTHIFLRQGHPLSEKKEIFKEELLPYPQVRFTQDGNNFPYFYEDLIESPDQETVIYTSDRGTLMNIVLETDAYASGSGLVIGEIKEYLRLIPLANSPQNELYVIYSAKRQLSEIAQKFMESLTVLLSQIKTN
>NZ_CP023011.2|WP_010719204.1|2109616_2109790_-|hypothetical-protein
MKNKFILSLDILTIGISVSESTISGYASTINEPSTVADSSQELTLLDKNVVAKVNIY
>NZ_CP023011.2|WP_095454257.1|2108140_2109373_-|hypothetical-protein
MRLDKMIVTFINALSIASGIGGARALPSLDNQNQGRGLGKVLDLENRNETTRLSDKTYSHKKLHSKHRNKGNLKHLDKIQDDVSRQPYSAKKFLHKKIKNLIKQEETDFKKLKEGISTESSIEVNQLQTNLRRVQNFCSKFRKLRNDIVIEYGKMTQQKVNLRKHKIKNKKMLKECYKEIKVLSTNKKHIDYLISNCKDMVNQLQESIESKKTHSVSTSKSTMTTSHTEQPTTTSHTEQPTTTSRTEQPTISLQETERILIRSKKLISQFNEKTQEINAFRRQEKELLLLLQDQYRTQFENPRNISDVKADLNEINRNIIPKLESEKFHIQAEIIKEVNHINSLEGQGKISPFEAKKFLNEYNKLNINFAKERNKRDISLKQNLSKKLESIVLNNSEKPIAQNTTISMTR
>NZ_CP023011.2|WP_094940264.1|2106306_2107029_-|ATP-binding-cassette-domain-containing-protein
MIELINVTKSYEGTQAVKNIHLTIEPGEIIGIVGKSGSGKSTLLRLLNLMEEPSSGEILIDSVAVQKLKKKEKRQQKQKMGMIFQNHNLLDNLKVYENVELPLKLQKKKNREKIDYLLNFVGMAHKAAVYPVKLSGGEKQRVSIARALTRDPEILLCDEATSSLDEENTESVIRLLHKVHEEFQPTIFFVSHELETVKSLCQRILVMENGELIGELRNHPQRFTEENLTYFEKIKRSLAQ
>NZ_CP023011.2|WP_094940265.1|2105638_2106310_-|ABC-transporter-permease-subunit
MIHSQSMMEYWPALLTSLEETGIMMAISMGVCVVGGLPLGLGLFLTNPKVRGHYPWIYWTLNFLVTVIRSFPYLLFVIALIPVTRAVLGKAFGPIPASVPLSIIAITIFARLVEQVLLDVSDETYALANSLGTTRFQYIWHFLLVEARSGLVLAYTTTTVSMVSYSTVMGVIGGGGIGDFAVRVGYQRYEYGVMYVAIVIMIFLVFILQMLGNFVAQTLDKRK
>NZ_CP023011.2|WP_094940266.1|2104814_2105627_-|hypothetical-protein
MKKFYLIGFAMIAILTLAACGGHSADKDKKEIKVAVQLESSKDILEIAKKEVEKQGYTIDIMEVSDNVAYNDAVQHDEADANFAQHEPFMAMFNQEKKADLVAVQPIYYFAGGFYSKNYKNADQLPKNAKVGIPSDPTNEGRALAILNKNGVIKLKDNMGFNGTVADIVDNPKNLQFERIDLLNLVKAYDEKDIAMVFCYPAYLEPAGLSTKDAILLEDEAASKHYALQLVTREGEKDSEKINVLKKAMTTKEVAEYIKKKSKGANIPAF
>NZ_CP023011.2|WP_094940267.1|2103744_2104551_-|hypothetical-protein
MKMKKLTGLLLAGIILSTGATTLASSPDVSAATVISENQYEKVMSFTKADLTAVTGIVLEPTEASIQRMYDSLKKERVWLALGYSSTEAQRITKRMAQSTYQAIGILTSMANNQNIQLKVVVINKFNYSTINIGTIGSVDKPTVPKDEPEKEDTNKPGDLALRALVKEIEIEIEYQKEKIKLDYEVKSNGKIKAEVKNEQTGLKLQDAKAQTYVETLFVGLDAKTSSQEEIKTHIMEQLHANQKGLKKFAFKVKYADKTKVDFKIKYK
>NZ_CP023011.2|WP_094940268.1|2103236_2103572_-|PadR-family-transcriptional-regulator
MGKSNQFKKGVLELCVLYLLKNKDRYGYEITQLVNKNIPLTEGALYPILRRFVKEGYCVTYLKESKGGPARKYYQITSLGKEYLADLNKEWMVFVENVALLKQEEDERANE
>NZ_CP023011.2|WP_192574426.1|2113386_2114037_-|orotate-phosphoribosyltransferase
MESINLNTIEKNIAKDLLAIEAVFLSPNEPFTWASGLKSPIYCDNRITMSYPKVRKAIAQGLAEKIKQAFPDVEVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDHGKGNQIEGRIFEGQKMVVIEDLISTGQSVLEATEAAKREGANVLGVAAIFTYELPAGEENFAKAELPLFTLTNYSVLIETALAEKYIDEAELALLKEWKKNPVDWLKQ
>NZ_CP023011.2|WP_010719209.1|2114018_2114735_-|orotidine-5'-phosphate-decarboxylase
MNQRPIIALDFSTWQEVEQFMQLFPEEEKLFVKIGMELFYQEGPIIVRWLKDAGHEVFLDLKLHDIPNTVEKAMRGLAKLGVDITCVHAAGGIKMMQAALRGLEEGTPAGKKRPLLLAITQLTSTSEADMHHDQLIQVPLEESVIHYAKCAEAAGLDGVVSSALEVSGIKAATRQDFICLSPGIRPEGSVAGDQTRIVTPAQARGIGSTFIVVGRPITQAKDPYQAYQTIKEEWSRSI
>NZ_CP023011.2|WP_010737540.1|2114731_2115661_-|dihydroorotate-dehydrogenase
MSNPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSIMVKATTPHARFGNPTPRVAETPSGMLNAIGLQNPGLEVVMNELLPELAVYPDLPIIANVAGACEEDYVEVCRKIGEAPNVKAIELNISCPNVKHGGIAFGTDPDVAFQLTKAVKKVASVPVYVKLSPNVTDIVPIAQAIESGGADGFTMINTLLGMRIDLKTRQPILANQTGGLSGPAIKPVAIRLIHQVAAVSELPIIGMGGVQTVDDVLEMFMAGASAVAVGTANFTDPYICPKLIEELPVRMAELGIESLQQLIKEVREERMK
>NZ_CP023011.2|WP_094940263.1|2115657_2116434_-|dihydroorotate-dehydrogenase-electron-transfer-subunit
MKQEVMTIIQQTQLAPRIYELTLKGELVKEMSIPGQFLHIRVPRSDLLLRRPISIHSIDQQNHTCQIIYRIEGEGTKEFSTLKAGDSLDVLGPLGNGFDLSGLSAGEEVFIVGGGIGIPPLYELAKQLNMRGVKVTNFLGFASKEVMYHEAKFHELGETRVATDDGTYGIHGNVGNLLMSTHKQPKAVFACGANGLLKTVEQLFVDHPNVQLSLESRMACGIGACYACVCHRPDDETGTKSVKVCDEGPIFKVGEVVL
>NZ_CP023011.2|WP_010737538.1|2116612_2119798_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEVVLVNSNPATIMTDQEIADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMELAESGILDELGIELLGTKLSAIDQAEDRDLFKKLMEELNQPIPESEIVTTVEEAVEFANKIGYPIIVRPAFTLGGTGGGMCKNEEELRVIAENGLSLSPVTQCLIERSIAGFKEIEYEVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQLLRDASLAIIRALKIEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEMKNPVTGTTYAEFEPALDYVVAKIPRWPFDKFENGERVLGTQMKATGEVMAIGRNIEESLLKAVRSLEIGTHHLELPELNMIDDSELIEKVVRAQDDRLFYVAEAIRRGYPIEELAELTKIDLFFLDKLLHIVELETELLEHPQDENVLRTVKQNGFTDQKIAELWKTEAKQIRELREKSDIKPVYKMVDTCAAEFASQTPYFYSSYEVENESERSAKDSVLVLGSGPIRIGQGVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIELEQPIGVIVQFGGQTAINLAEPLVQAGVKILGTTIEDLDRAENRDLFEQALRSLEVPQPLGDTATSKEEAVGIASKIGYPVLVRPSYVLGGRAMEIVENQQDLEDYMEHAVKASPEHPVLIDRYLLGSECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQALSAEIKQTIEDYTIRLARGLNCIGMMNIQFVIHDNQVYVIEVNPRASRTVPFLSKVTGIPMAQIATKAILGEKLSDLGFTNGLYPESNAVHVKAPVFSFTKLQQVDTYLGPEMKSTGEVMGSDQNLDKALYKAFEASGLRLPDYGAVLFTIADETKEEALALAKRFSEIGYSLLATKHTAAYFEKNGLIVTPVAKISEKATEKNVVELIREGKAQVVVNTIDKDRGNASKDGFIIRREAVEHGIPLFTSLDTADAIIRVMESRAFSTQAI
>NZ_CP023011.2|WP_095454260.1|2119800_2120877_-|carbamoyl-phosphate-synthase-small-subunit
MERLLILEDGTVFKGKAFGANNNVFGEIVFTTSMTGYQETITDQSFNGQIITFTYPMVGNYGVNRDDYESIAPTCKGVVVKEHARVASNWRSQMTLDEFLKRKGIPGISGIDTRALTRKIRQVGTMKASIVDAGDSFEHAYDQLKATVLATNQVQQVSTSKPYPSPGTGKNVAVIDFGLKHSILRELSKRNCNLTVLPYNTDAKTILSLAPDGVMLTNGPGDPKDVPEAIEMIREIQGKIPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVREIATGRIDFTSQNHGYAVDEKTVDPDQLLITHVEVNDGTVEGIRHRHYPAFSVQFHPDAAPGPHDALHLFDEFMEMMDAGEEK
>NZ_CP023011.2|WP_053766057.1|2120882_2122163_-|dihydroorotase
MKTLIKNGQINTRKNETTPAEIWIENGKIKAIGEGFSEAEFDEVFDAKGQLITPGLVDVHVHLREPGFTYKETIAAGTKAAARGGFTTVCAMPNLNPVPDTPEKLEQVYDLIKRDAVVKVLQYAPITENLRSEVLVDQEAMIKAGAFAFTNDGVGVQTAGTMYQAMKEAAKNNKALVAHTEDESLLFGGVMHAGDKAKELGLPGILSVTESSQIARDLLLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWKMNPPLRGKEDREALIEGLLDGTIDCIATDHAPHGLEEKSKSFLESPFGIVGSETAFQLIYTHFVETNRFTLEQVINWMATKPAEIFQLEAGTLTVGAPADVAVFDIEHSSTIDKKDFLSKGENTPFVGWNVKGETLGTFVDGKLAWHKGE
>NZ_CP023011.2|WP_010719215.1|2122181_2123108_-|aspartate-carbamoyltransferase-catalytic-subunit
MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQKPQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALGVDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGYFEGLKVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDEEFEVYGHYLPLDELLEQVDVMMMLRVQHERHDGKESFSKEAYHQEYGLTVERAKKLQKHAIIMHPAPVNRDVELADSLVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA
>NZ_CP023011.2|WP_010719216.1|2123120_2124404_-|uracil-transporter
MSEQKKFHNHDAVLDIHDRPKTGHWIGLSLQHLFTMFGATVLVPILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQMLMKTDGYPAIAQGAVTTGLVYLIVAWIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGNYDFKYIAVALITLALTIFFNMWLKGFLGLIPILLGIICGYLVALLFGIVDTKPIADAAWFALPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLHKTLMGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKLSALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGLVFEVGTFTLSAMALATVLGIILNLILPETSRSEEK
>NZ_CP023011.2|WP_010719217.1|2124417_2124957_-|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR
MQAKEVVDQVTMKRALTRITYEIIERNQTIQDVVLIGIKTRGIYIASRVADRLKQLEGIEVPVGELDITLYRDDKKETPAEAELHSSDIPVSLEGKEVILIDDVLYTGRTIRAAMDAVMDYGRPRKISLAVLVDRGHRELPIRADYVGKNIPTAKTEEILVEMQELDGKDRIMILKEEE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP023011_4	4.4\|2113072\|30\|NZ_CP023011\|CRISPRCasFinder	2113072-2113101	30	NZ_LR135334	Enterococcus faecium isolate E7471 plasmid 4	48147-48176	0	1.0
NZ_CP023011_4	4.4\|2113072\|30\|NZ_CP023011\|CRISPRCasFinder	2113072-2113101	30	NZ_LR135205	Enterococcus faecium isolate E7171 plasmid 3	42408-42437	0	1.0
NZ_CP023011_4	4.6\|2113080\|28\|NZ_CP023011\|PILER-CR	2113080-2113107	28	NZ_LR135334	Enterococcus faecium isolate E7471 plasmid 4	48147-48174	0	1.0
NZ_CP023011_4	4.6\|2113080\|28\|NZ_CP023011\|PILER-CR	2113080-2113107	28	NZ_LR135205	Enterococcus faecium isolate E7171 plasmid 3	42408-42435	0	1.0
NZ_CP023011_3	3.1\|939138\|30\|NZ_CP023011\|PILER-CR,CRISPRCasFinder,CRT	939138-939167	30	MN582070	Myoviridae sp. ctThM1, complete genome	79022-79051	6	0.8
NZ_CP023011_3	3.4\|939336\|30\|NZ_CP023011\|CRISPRCasFinder,CRT	939336-939365	30	NZ_CP045723	Pantoea eucalypti strain LMG 24197 plasmid unnamed3, complete sequence	50282-50311	6	0.8
NZ_CP023011_4	4.2\|2113074\|38\|NZ_CP023011\|CRT	2113074-2113111	38	NZ_LR135334	Enterococcus faecium isolate E7471 plasmid 4	48137-48174	6	0.842
NZ_CP023011_4	4.2\|2113074\|38\|NZ_CP023011\|CRT	2113074-2113111	38	NZ_LR135205	Enterococcus faecium isolate E7171 plasmid 3	42398-42435	6	0.842
NZ_CP023011_4	4.5\|2113138\|30\|NZ_CP023011\|CRISPRCasFinder	2113138-2113167	30	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1547775-1547804	7	0.767
NZ_CP023011_3	3.1\|939138\|30\|NZ_CP023011\|PILER-CR,CRISPRCasFinder,CRT	939138-939167	30	JN638751	Bacillus phage G, complete genome	7294-7323	8	0.733
NZ_CP023011_3	3.2\|939204\|30\|NZ_CP023011\|PILER-CR,CRISPRCasFinder,CRT	939204-939233	30	MN530981	Campylobacter phage DA10, complete genome	23604-23633	8	0.733
NZ_CP023011_3	3.1\|939138\|30\|NZ_CP023011\|PILER-CR,CRISPRCasFinder,CRT	939138-939167	30	NC_021789	Cellulophaga phage phi19:3, complete genome	7479-7508	9	0.7

1. spacer 4.4|2113072|30|NZ_CP023011|CRISPRCasFinder matches to NZ_LR135334 (Enterococcus faecium isolate E7471 plasmid 4) position: , mismatch: 0, identity: 1.0

ctaccagaagtaccaaacattaagccactc	CRISPR spacer
ctaccagaagtaccaaacattaagccactc	Protospacer
******************************

2. spacer 4.4|2113072|30|NZ_CP023011|CRISPRCasFinder matches to NZ_LR135205 (Enterococcus faecium isolate E7171 plasmid 3) position: , mismatch: 0, identity: 1.0

ctaccagaagtaccaaacattaagccactc	CRISPR spacer
ctaccagaagtaccaaacattaagccactc	Protospacer
******************************

3. spacer 4.6|2113080|28|NZ_CP023011|PILER-CR matches to NZ_LR135334 (Enterococcus faecium isolate E7471 plasmid 4) position: , mismatch: 0, identity: 1.0

accagaagtaccaaacattaagccactc	CRISPR spacer
accagaagtaccaaacattaagccactc	Protospacer
****************************

4. spacer 4.6|2113080|28|NZ_CP023011|PILER-CR matches to NZ_LR135205 (Enterococcus faecium isolate E7171 plasmid 3) position: , mismatch: 0, identity: 1.0

accagaagtaccaaacattaagccactc	CRISPR spacer
accagaagtaccaaacattaagccactc	Protospacer
****************************

5. spacer 3.1|939138|30|NZ_CP023011|PILER-CR,CRISPRCasFinder,CRT matches to MN582070 (Myoviridae sp. ctThM1, complete genome) position: , mismatch: 6, identity: 0.8

ttttcatagttatttagcattgcattatct	CRISPR spacer
ttttcatcgttatttagaattgcttgcttt	Protospacer
******* ********* ***** *  *.*

6. spacer 3.4|939336|30|NZ_CP023011|CRISPRCasFinder,CRT matches to NZ_CP045723 (Pantoea eucalypti strain LMG 24197 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

cggaatctcgcgttttgaactgctagtttt	CRISPR spacer
aaaattctcgcgttttgaacttctactttt	Protospacer
 ..* **************** *** ****

7. spacer 4.2|2113074|38|NZ_CP023011|CRT matches to NZ_LR135334 (Enterococcus faecium isolate E7471 plasmid 4) position: , mismatch: 6, identity: 0.842

accagaagtaccaaacattaagccactcgttttggaag	CRISPR spacer
accagaagtaccaaacattaagccactcggtgttagaa	Protospacer
***************************** * * ..*.

8. spacer 4.2|2113074|38|NZ_CP023011|CRT matches to NZ_LR135205 (Enterococcus faecium isolate E7171 plasmid 3) position: , mismatch: 6, identity: 0.842

accagaagtaccaaacattaagccactcgttttggaag	CRISPR spacer
accagaagtaccaaacattaagccactcggtgttagaa	Protospacer
***************************** * * ..*.

9. spacer 4.5|2113138|30|NZ_CP023011|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 7, identity: 0.767

taaatgagagcaacggcaatttccatttga	CRISPR spacer
taattgagaggaacggcaatttcagatcgt	Protospacer
*** ****** ************ . *.*

10. spacer 3.1|939138|30|NZ_CP023011|PILER-CR,CRISPRCasFinder,CRT matches to JN638751 (Bacillus phage G, complete genome) position: , mismatch: 8, identity: 0.733

ttttcatagttatttagcattgcattatct	CRISPR spacer
gaaagatatttatttagcattgtattatca	Protospacer
     *** *************.******

11. spacer 3.2|939204|30|NZ_CP023011|PILER-CR,CRISPRCasFinder,CRT matches to MN530981 (Campylobacter phage DA10, complete genome) position: , mismatch: 8, identity: 0.733

taatgccgatttgattttacttcctttata	CRISPR spacer
aattatttttttcattttacttcctttata	Protospacer
 * *...  *** *****************

12. spacer 3.1|939138|30|NZ_CP023011|PILER-CR,CRISPRCasFinder,CRT matches to NC_021789 (Cellulophaga phage phi19:3, complete genome) position: , mismatch: 9, identity: 0.7

ttttcatagttatttagcattgcattatct	CRISPR spacer
aacaagtagttatttagcaatgcactatcc	Protospacer
  .  .************* ****.****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 4820

Anguillid_herpesvirus(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719910.1\|773_1217_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	7.1e-25	46.2
WP_010738334.1\|1330_2242_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_095454040.1\|2744_4820_-	LTA synthase family protein	W6LM83	Streptococcus_phage	1.9e-160	47.4

DBSCAN-SWA_2

12565 : 13642

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053765873.1\|12565_13642_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-25	32.7

DBSCAN-SWA_3

16968 : 18136

Lactobacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719925.1\|16968_17673_-	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	1.9e-48	46.1
WP_010719926.1\|17695_18136_-	nucleoside 2-deoxyribosyltransferase	A0A1D3SPR3	Enterococcus_phage	5.6e-22	38.8

DBSCAN-SWA_4

37344 : 38229

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088744994.1\|37344_38229_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.7e-15	24.6

DBSCAN-SWA_5

42275 : 52761

Planktothrix_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454046.1\|42275_44132_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.1e-25	35.9
WP_094940195.1\|44115_46092_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.5e-18	35.5
WP_094940194.1\|46174_47005_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_094940087.1\|47488_48706_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	5.3e-78	42.2
WP_034699699.1\|49035_50133_-	agmatine deiminase	M1HPC5	Acanthocystis_turfacea_Chlorella_virus	2.9e-99	49.2
WP_081127780.1\|50086_51505_-	APC family permease	NA	NA	NA	NA
WP_034866258.1\|51741_52761_-	putrescine carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.8e-15	26.1

DBSCAN-SWA_6

70882 : 71293

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719969.1\|70882_71293_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	4.3e-32	51.1

DBSCAN-SWA_7

87422 : 96199

Lactococcus_phage(40.0%)

integrase

attL 83660:83673|attR 96469:96482

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
83660:83673	attL	NA	NA	NA	NA
WP_002344958.1\|87422_88292_-	hypothetical protein	A0A1P8BL54	Lactococcus_phage	1.5e-13	37.2
WP_002344957.1\|88445_88748_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002287690.1\|88949_89747_+	helix-turn-helix transcriptional regulator	Q9AZH9	Lactococcus_phage	2.6e-09	39.0
WP_002344956.1\|89797_90940_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	3.6e-60	36.3
WP_094940183.1\|91037_92429_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_010738384.1\|92433_92904_-	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_088745003.1\|92890_94126_-	cysteine desulfurase	Q2XUY6	environmental_halophage	1.7e-116	48.2
WP_034699632.1\|94122_95412_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_094940182.1\|95425_96199_-	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	1.3e-08	28.8
96469:96482	attR	NA	NA	NA	NA

DBSCAN-SWA_8

100014 : 100371

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719983.1\|100014_100371_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-24	44.8

DBSCAN-SWA_9

105231 : 106875

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025480241.1\|105231_105717_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	6.0e-17	36.7
WP_034699620.1\|105933_106875_+	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	6.1e-82	50.5

DBSCAN-SWA_10

111631 : 118303

Powai_lake_megavirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454052.1\|111631_112579_-	alpha/beta hydrolase	A0A167RJ59	Powai_lake_megavirus	5.5e-67	43.2
WP_034699610.1\|113111_114356_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	2.0e-101	54.0
WP_094940176.1\|114587_115619_-	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	5.5e-60	43.3
WP_095454053.1\|115810_116650_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_034699602.1\|116642_117716_-	peptide chain release factor 1	NA	NA	NA	NA
WP_010719999.1\|117718_118303_-	thymidine kinase	A0A249XZX5	Enterococcus_phage	1.3e-45	49.7

DBSCAN-SWA_11

130281 : 132192

Bradyrhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940173.1\|130281_132192_-	glucosaminidase domain-containing protein	A0A1X9SGZ2	Bradyrhizobium_phage	4.2e-13	35.3

DBSCAN-SWA_12

147844 : 151458

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010738420.1\|147844_149734_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.4e-63	31.5
WP_034699574.1\|149730_151458_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.7e-48	27.4

DBSCAN-SWA_13

159390 : 161700

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720037.1\|159390_160215_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	5.3e-74	54.9
WP_010738428.1\|160227_161700_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	7.0e-109	45.5

DBSCAN-SWA_14

167387 : 169337

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720044.1\|167387_169013_-	chaperonin GroEL	A0A219YK78	uncultured_virus	1.2e-154	56.2
WP_010738436.1\|169052_169337_-	co-chaperone GroES	A0A221S4M3	uncultured_virus	6.8e-13	40.2

DBSCAN-SWA_15

173155 : 181096

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720049.1\|173155_173965_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	2.2e-32	33.5
WP_010720050.1\|174015_174888_-	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_010720051.1\|174888_176202_-	hypothetical protein	NA	NA	NA	NA
WP_010738440.1\|176198_178034_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	2.6e-36	37.9
WP_010720053.1\|178037_178742_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.4e-45	42.0
WP_094940160.1\|179118_179808_-	hypothetical protein	NA	NA	NA	NA
WP_010738442.1\|180238_181096_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.9e-10	22.5

DBSCAN-SWA_16

188201 : 189395

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720061.1\|188201_189395_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.5e-29	37.0

DBSCAN-SWA_17

193592 : 197146

Enterococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010738447.1\|193592_193817_+	glutaredoxin-like protein NrdH	A0A0M7REK7	Lactobacillus_phage	3.0e-11	41.3
WP_010720067.1\|193963_196123_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	7.0e-267	63.7
WP_010720068.1\|196177_197146_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.4e-126	70.1

DBSCAN-SWA_18

213832 : 217997

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720086.1\|213832_214546_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	1.2e-18	43.7
WP_094940219.1\|214691_215393_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_053765776.1\|215822_217352_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.0e-46	27.7
WP_080704604.1\|217694_217997_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SAB3	Streptococcus_phage	1.1e-13	43.9

DBSCAN-SWA_19

235812 : 240645

Pneumococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720160.1\|235812_236316_-	QueT transporter family protein	E7DN70	Pneumococcus_phage	4.5e-07	34.0
WP_094940845.1\|236743_237721_+	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
WP_094940844.1\|238005_240645_-	ATP-dependent RecD-like DNA helicase	A0A218KCE8	Bacillus_phage	2.8e-60	28.8

DBSCAN-SWA_20

253941 : 255105

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720178.1\|253941_255105_-	chorismate synthase	A0A291AU41	Pandoravirus	3.1e-35	34.9

DBSCAN-SWA_21

259761 : 261150

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454063.1\|259761_261150_+	Y-family DNA polymerase	M1Q231	Streptococcus_phage	6.2e-91	41.8

DBSCAN-SWA_22

273531 : 273873

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940837.1\|273531_273873_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SEX8	Streptococcus_phage	1.1e-12	40.0

DBSCAN-SWA_23

294592 : 298025

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720209.1\|294592_295510_+	cysteine synthase family protein	C3U2M1	Lactococcus_phage	6.8e-62	42.1
WP_034699393.1\|295565_296714_+	cystathionine gamma-synthase	NA	NA	NA	NA
WP_010720211.1\|296877_297336_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_094940827.1\|297554_298025_+	glutathione peroxidase	A0A1S7DM81	Molluscum_contagiosum_virus	5.8e-09	28.3

DBSCAN-SWA_24

304957 : 307162

Cafeteria_roenbergensis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720215.1\|304957_307162_-	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	1.8e-44	26.8

DBSCAN-SWA_25

325916 : 333873

Planktothrix_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720230.1\|325916_326618_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.1e-33	39.0
WP_034867134.1\|326781_327387_+	cysteine hydrolase	NA	NA	NA	NA
WP_010720232.1\|327471_328497_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_034699243.1\|328819_330925_+	C40 family peptidase	Q9ZXE4	Bacillus_phage	5.4e-22	46.2
WP_095454068.1\|331297_333106_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_010720235.1\|333120_333873_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.2e-33	37.7

DBSCAN-SWA_26

338602 : 342777

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010736934.1\|338602_339628_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	9.7e-41	29.7
WP_010720244.1\|339624_340299_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.6e-47	43.9
WP_095454069.1\|340440_342777_+	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	5.8e-33	37.9

DBSCAN-SWA_27

351629 : 357066

Vibrio_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940855.1\|351629_353807_-	PTS transporter subunit EIIC	A0A2I7SAJ6	Vibrio_phage	1.5e-06	38.1
WP_095454072.1\|354113_356408_+	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_094940856.1\|356400_357066_+	beta-phosphoglucomutase	M1H9H9	Acanthocystis_turfacea_Chlorella_virus	9.4e-13	28.1

DBSCAN-SWA_28

365087 : 366344

Pectobacterium_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010736915.1\|365087_366344_-\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	9.0e-81	42.7

DBSCAN-SWA_29

395130 : 405247

Streptococcus_phage(40.0%)

integrase

attL 385902:385951|attR 401880:401929

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
385902:385951	attL	NA	NA	NA	NA
WP_094940868.1\|395130_396387_+	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	4.1e-33	28.6
WP_161298806.1\|396913_397087_+	hypothetical protein	NA	NA	NA	NA
WP_094940870.1\|397957_398206_+	hypothetical protein	NA	NA	NA	NA
WP_094940871.1\|398195_398516_+	hypothetical protein	NA	NA	NA	NA
WP_094940873.1\|399269_401201_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.8e-30	27.3
WP_105198786.1\|401257_401419_+	DNA repair protein RadC	NA	NA	NA	NA
WP_094940875.1\|401536_401857_+\|integrase	tyrosine-type recombinase/integrase	J7KBT5	Streptococcus_phage	4.5e-13	50.8
WP_010720283.1\|401894_402254_-	50S ribosomal protein L20	NA	NA	NA	NA
401880:401929	attR	NA	NA	NA	NA
WP_002289309.1\|402308_402509_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_010720284.1\|402580_403105_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	1.1e-13	32.7
WP_010736889.1\|403457_404363_-	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_025480266.1\|404587_405247_-	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	7.0e-61	53.2

DBSCAN-SWA_30

414593 : 415739

uncultured_Mediterranean_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720296.1\|414593_415739_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	9.6e-82	40.9

DBSCAN-SWA_31

436586 : 446500

Lonomia_obliqua_multiple_nucleopolyhedrovirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_105198789.1\|436586_440456_+	hypothetical protein	A0A126FC74	Lonomia_obliqua_multiple_nucleopolyhedrovirus	3.8e-29	25.7
WP_095454096.1\|440562_443199_-	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	3.8e-81	29.9
WP_095454324.1\|443945_444977_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_095454097.1\|445492_446500_-	leukocidin family pore-forming toxin	A0A2H4PQH7	Staphylococcus_phage	4.6e-27	31.4

DBSCAN-SWA_32

458305 : 461807

Lactobacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720330.1\|458305_458668_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A291I9M9	Lactobacillus_phage	3.4e-09	37.8
WP_095454104.1\|458678_459800_-	alanine racemase	NA	NA	NA	NA
WP_010720332.1\|459815_460166_-	holo-ACP synthase	NA	NA	NA	NA
WP_010720333.1\|460295_461807_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	3.5e-63	36.8

DBSCAN-SWA_33

468064 : 469438

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454107.1\|468064_468664_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	2.6e-22	35.5
WP_010720341.1\|468808_469438_-	uridine kinase	A0A1V0SAA3	Catovirus	6.3e-35	40.7

DBSCAN-SWA_34

478512 : 480474

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172595712.1\|478512_480474_-	KUP/HAK/KT family potassium transporter	M1HZV6	Acanthocystis_turfacea_Chlorella_virus	1.0e-62	34.4

DBSCAN-SWA_35

483949 : 484513

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720354.1\|483949_484513_+	peptide deformylase	E3SLL2	Synechococcus_phage	1.4e-12	41.2

DBSCAN-SWA_36

490263 : 494618

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454115.1\|490263_490989_-	NAD-dependent protein deacylase	A0A068EPD4	Bacillus_phage	5.1e-20	27.8
WP_010736843.1\|491210_491513_+	hypothetical protein	NA	NA	NA	NA
WP_081128330.1\|492269_493865_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_095454116.1\|493877_494618_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.0e-31	41.1

DBSCAN-SWA_37

500775 : 503934

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720372.1\|500775_501777_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	3.1e-07	25.3
WP_010720373.1\|501789_502392_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_034698687.1\|502699_503143_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_010720375.1\|503220_503934_-	trehalose operon repressor	A0A291LID1	Streptomyces_phage	1.6e-05	39.7

DBSCAN-SWA_38

507977 : 512753

Wolbachia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454325.1\|507977_510077_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.4e-54	40.0
WP_094940933.1\|510140_512753_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	3.6e-39	25.6

DBSCAN-SWA_39

518882 : 519862

Chrysochromulina_ericina_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454117.1\|518882_519644_-	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	2.0e-14	24.1
WP_010720389.1\|519640_519862_-	DUF2829 domain-containing protein	A0A0S2MV93	Bacillus_phage	6.7e-08	36.3

DBSCAN-SWA_40

522875 : 523610

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720393.1\|522875_523610_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	9.7e-27	30.9

DBSCAN-SWA_41

531866 : 534518

Anomala_cuprea_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940674.1\|531866_532622_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.9e-16	28.4
WP_010720403.1\|532618_533575_-	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_094940673.1\|533567_534518_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	1.6e-69	44.0

DBSCAN-SWA_42

548235 : 548922

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720414.1\|548235_548922_-	ribonuclease III	A0A2K9L8W0	Tupanvirus	9.1e-27	33.0

DBSCAN-SWA_43

552923 : 554873

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720418.1\|552923_553868_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-20	35.6
WP_010736807.1\|553868_554873_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.1e-18	32.6

DBSCAN-SWA_44

574740 : 576425

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940662.1\|574740_575610_-	energy-coupling factor ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.9e-13	27.2
WP_034697737.1\|575585_576425_-	energy-coupling factor ABC transporter ATP-binding protein	F2Y302	Organic_Lake_phycodnavirus	9.1e-13	29.5

DBSCAN-SWA_45

599872 : 608678

Klosneuvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720459.1\|599872_601060_-	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	2.4e-11	24.4
WP_010720460.1\|601231_603316_-	elongation factor G	E4ZFJ7	Streptococcus_phage	4.2e-67	29.4
WP_010720461.1\|603394_603865_-	30S ribosomal protein S7	NA	NA	NA	NA
WP_002294318.1\|603956_604370_-	30S ribosomal protein S12	NA	NA	NA	NA
WP_010736793.1\|604678_605362_+	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_010720463.1\|605499_606081_+	recombinase family protein	A0A219YA40	Aeromonas_phage	5.0e-18	32.0
WP_010720464.1\|606389_607076_+	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_010720465.1\|607130_607838_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_010736792.1\|607859_608678_-	purine-nucleoside phosphorylase	Q5YBA4	Grouper_iridovirus	1.2e-57	45.2

DBSCAN-SWA_46

612236 : 617974

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720470.1\|612236_613799_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.9e-21	32.5
WP_010720471.1\|614423_615506_-	BMP family protein	NA	NA	NA	NA
WP_010720472.1\|615579_615978_-	cytidine deaminase	NA	NA	NA	NA
WP_094940656.1\|615995_616658_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_034697695.1\|616672_617974_-	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	1.2e-123	55.2

DBSCAN-SWA_47

623828 : 625394

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940653.1\|623828_625394_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	4.9e-20	32.2

DBSCAN-SWA_48

630218 : 631385

Clostridium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053766562.1\|630218_631385_-	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	3.2e-32	27.4

DBSCAN-SWA_49

641786 : 649341

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720489.1\|641786_643409_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.9e-46	25.8
WP_192574428.1\|644682_644781_-	hypothetical protein	NA	NA	NA	NA
WP_094940645.1\|645043_645907_-	DegV family protein	NA	NA	NA	NA
WP_010720491.1\|646243_647536_-	adenylosuccinate synthase	G5CQQ4	Megavirus	6.2e-69	35.7
WP_010720492.1\|647973_649341_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	9.3e-132	55.0

DBSCAN-SWA_50

654364 : 662785

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720497.1\|654364_654877_-	single-stranded DNA-binding protein	A0A2H4J1H8	uncultured_Caudovirales_phage	1.8e-48	64.1
WP_010720498.1\|654928_655228_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_010720499.1\|655627_658126_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	4.5e-100	34.0
WP_010736776.1\|658145_660092_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	3.7e-142	43.8
WP_034697664.1\|660092_661214_-	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_010720502.1\|661200_661443_-	S4 domain-containing protein YaaA	NA	NA	NA	NA
WP_010720503.1\|661654_662785_-	DNA polymerase III subunit beta	B4UTW9	Rhizobium_phage	6.5e-30	28.1

DBSCAN-SWA_51

675346 : 686279

Bacillus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454126.1\|675346_676114_+	ParA family protein	Q8JL10	Natrialba_phage	1.1e-28	32.8
WP_010720515.1\|676100_676991_+	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	8.4e-17	33.5
WP_010720516.1\|677110_677302_+	DUF951 domain-containing protein	NA	NA	NA	NA
WP_010720517.1\|677310_678411_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_010720518.1\|678497_679193_+	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_095454127.1\|679513_680998_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	6.6e-99	42.6
WP_094940640.1\|681355_682585_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_053766574.1\|682814_684086_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.7e-93	53.4
WP_025480278.1\|684394_685603_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	3.3e-24	27.0
WP_010736768.1\|685589_686279_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.6e-39	39.8

DBSCAN-SWA_52

693385 : 699760

Enterobacteria_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940892.1\|693385_695866_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	8.1e-126	38.0
WP_014834383.1\|696058_696982_+	U32 family peptidase	NA	NA	NA	NA
WP_095454128.1\|697000_698242_+	U32 family peptidase	Q6DW11	Phage_TP	2.8e-42	32.8
WP_010720713.1\|698413_699760_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.4e-42	27.6

DBSCAN-SWA_53

730169 : 740963

Pithovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940706.1\|730169_730973_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.9e-07	26.0
WP_034700142.1\|730965_731880_-	ABC transporter permease	NA	NA	NA	NA
WP_094940707.1\|731898_732867_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010720685.1\|733364_733607_+	hypothetical protein	NA	NA	NA	NA
WP_010720684.1\|733612_737230_+	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	9.0e-49	24.4
WP_010720683.1\|737309_740963_+	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	1.4e-62	24.7

DBSCAN-SWA_54

745199 : 745667

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720679.1\|745199_745667_+	DNA starvation/stationary phase protection protein	A0A291I9P0	Lactobacillus_phage	1.9e-15	32.2

DBSCAN-SWA_55

757060 : 765133

Amsacta_moorei_entomopoxvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940715.1\|757060_757945_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	1.1e-24	33.6
WP_094940716.1\|758528_759962_+	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_094940718.1\|760084_760453_-	hypothetical protein	NA	NA	NA	NA
WP_094940719.1\|760704_762354_+	hypothetical protein	A0A0N9R0S5	Chrysochromulina_ericina_virus	1.7e-15	27.8
WP_010720660.1\|762655_763591_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.8e-25	34.8
WP_010720659.1\|763583_764354_+	ABC transporter permease	NA	NA	NA	NA
WP_094940720.1\|764614_765133_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.7e-17	34.9

DBSCAN-SWA_56

770990 : 775352

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_105198793.1\|770990_775352_+	type VII secretion protein EssC	A0A217ERB2	Bacillus_phage	5.8e-18	29.5

DBSCAN-SWA_57

782528 : 785308

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940730.1\|782528_783773_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	4.2e-115	57.5
WP_010720640.1\|783769_784576_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	5.6e-44	41.2
WP_010720639.1\|784777_785308_+	dUTP diphosphatase	J9PV85	Bacillus_phage	1.4e-43	57.1

DBSCAN-SWA_58

790446 : 791859

Moumouvirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053765951.1\|790446_791859_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	1.3e-48	31.8

DBSCAN-SWA_59

796003 : 798554

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737266.1\|796003_797272_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	8.5e-63	35.4
WP_010720625.1\|797264_798554_+	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	1.1e-06	28.1

DBSCAN-SWA_60

802090 : 803131

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720621.1\|802090_803131_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	2.4e-127	68.9

DBSCAN-SWA_61

809074 : 809881

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940739.1\|809074_809881_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.1e-34	36.3

DBSCAN-SWA_62

815011 : 820285

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737272.1\|815011_815692_+	metal ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.7e-12	28.4
WP_010720612.1\|815664_816489_+	metal ABC transporter permease	NA	NA	NA	NA
WP_010720611.1\|816654_817473_+	pur operon repressor	A0A1V0SKE5	Klosneuvirus	1.6e-06	27.1
WP_094940743.1\|817849_819223_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L277	Tupanvirus	5.8e-33	36.9
WP_010737274.1\|819316_820285_+	ribose-phosphate diphosphokinase	A0A2K9L8D8	Tupanvirus	8.2e-42	35.6

DBSCAN-SWA_63

825580 : 834739

Abalone_herpesvirus(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720602.1\|825580_826195_+	guanylate kinase	A0A143DIC6	Abalone_herpesvirus	4.9e-24	34.6
WP_010720601.1\|826199_826505_+	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_094940746.1\|826750_829159_+	primosomal protein N'	NA	NA	NA	NA
WP_010720599.1\|829172_829664_+	peptide deformylase	E3SLL2	Synechococcus_phage	6.7e-16	44.1
WP_094940747.1\|829656_830598_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	8.9e-09	28.8
WP_010720597.1\|830597_831956_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_010720596.1\|831968_832709_+	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_034700028.1\|832705_834739_+	Stk1 family PASTA domain-containing Ser/Thr kinase	A0A1V0SDC3	Indivirus	6.4e-20	32.3

DBSCAN-SWA_64

838806 : 840369

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940749.1\|838806_840369_+	C40 family peptidase	B5LJD6	Mycobacterium_phage	3.0e-17	50.5

DBSCAN-SWA_65

854072 : 861936

Cafeteria_roenbergensis_virus(25.0%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940756.1\|854072_855515_+\|tRNA	tRNA lysidine(34) synthetase TilS	E3T4I1	Cafeteria_roenbergensis_virus	1.6e-09	24.3
WP_010737292.1\|855514_856060_+	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	5.9e-05	23.4
WP_010720576.1\|856150_858262_+\|protease	ATP-dependent zinc metalloprotease FtsH	A9YVR1	Ostreococcus_tauri_virus	8.5e-108	49.9
WP_010720575.1\|858437_859325_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_094940758.1\|859325_860321_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_095454134.1\|860439_861936_+\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	2.8e-89	38.4

DBSCAN-SWA_66

870621 : 871815

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034868017.1\|870621_871815_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	6.6e-150	70.4

DBSCAN-SWA_67

876006 : 879491

Cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034700517.1\|876006_877719_+	ABC transporter ATP-binding protein	A0A1M7XV31	Cedratvirus	3.9e-10	29.1
WP_094940943.1\|877721_879491_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-52	29.2

DBSCAN-SWA_68

888426 : 896082

Staphylococcus_phage(75.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010721030.1\|888426_888996_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	1.4e-33	41.7
WP_010736968.1\|888995_889952_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	3.3e-43	58.1
WP_010721028.1\|890198_890849_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_034700501.1\|891231_893232_+	muramidase-2	A0A0A7RUS8	Clostridium_phage	1.2e-13	39.1
WP_094940938.1\|893667_896082_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	71.9

DBSCAN-SWA_69

928189 : 929323

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454138.1\|928189_929323_-	alcohol dehydrogenase catalytic domain-containing protein	E3SJ82	Synechococcus_phage	1.2e-10	24.8

DBSCAN-SWA_70

947707 : 950251

Only_Syngen_Nebraska_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940228.1\|947707_950251_+	HAD-IC family P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	5.9e-55	28.0

DBSCAN-SWA_71

955751 : 957065

Moraxella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737017.1\|955751_957065_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	3.6e-48	32.8

DBSCAN-SWA_72

976243 : 979371

Paramecium_bursaria_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720960.1\|976243_976960_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	5.9e-29	34.7
WP_095454146.1\|977472_979371_+	mannonate oxidoreductase	F2Y0V3	Organic_Lake_phycodnavirus	1.7e-19	31.0

DBSCAN-SWA_73

997229 : 1003651

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737045.1\|997229_998516_-	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.5e-22	29.0
WP_002317110.1\|998968_999448_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_192574429.1\|999604_1000516_+	EcsC family protein	NA	NA	NA	NA
WP_095454151.1\|1000815_1002408_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.0e-125	50.3
WP_095454152.1\|1002400_1003651_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	3.7e-26	25.5

DBSCAN-SWA_74

1007692 : 1008919

Acidithiobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454329.1\|1007692_1008919_+	AAA family ATPase	K4I1H4	Acidithiobacillus_phage	6.0e-21	26.2

DBSCAN-SWA_75

1047007 : 1047349

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720913.1\|1047007_1047349_+	YlbF family regulator	A0A1X9I5Y8	Streptococcus_phage	1.7e-10	35.8

DBSCAN-SWA_76

1061479 : 1062217

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720904.1\|1061479_1062217_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.4e-27	28.6

DBSCAN-SWA_77

1078750 : 1080046

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940555.1\|1078750_1080046_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	2.9e-106	49.3

DBSCAN-SWA_78

1084091 : 1086305

Orpheovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720880.1\|1084091_1086305_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	1.3e-10	35.8

DBSCAN-SWA_79

1090157 : 1096943

Orpheovirus(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720876.1\|1090157_1091450_+\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	3.2e-25	26.3
WP_034699943.1\|1091464_1093231_+\|tRNA	aspartate--tRNA ligase	A0A2I2L4Y8	Orpheovirus	2.5e-12	28.1
WP_010720874.1\|1093678_1094554_+	YitT family protein	NA	NA	NA	NA
WP_094940552.1\|1094996_1096943_+	acetyltransferase	W6MVL2	Pseudomonas_phage	1.5e-26	28.7

DBSCAN-SWA_80

1103630 : 1106825

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940549.1\|1103630_1106825_+	DEAD/DEAH box helicase	A0A2L1IWL4	Gordonia_phage	2.2e-35	27.1

DBSCAN-SWA_81

1124244 : 1124991

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737112.1\|1124244_1124991_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.4e-10	24.2

DBSCAN-SWA_82

1129788 : 1130388

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737115.1\|1129788_1130388_+	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	8.7e-34	45.6

DBSCAN-SWA_83

1142729 : 1150724

Hokovirus(33.33%)

lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720832.1\|1142729_1143755_+	sensor histidine kinase	A0A1V0SGX0	Hokovirus	7.7e-06	23.1
WP_010720831.1\|1143843_1144710_+	glucose transporter GlcU	NA	NA	NA	NA
WP_010720830.1\|1144746_1146126_+	amino acid permease	NA	NA	NA	NA
WP_010720829.1\|1146346_1147534_-	toxic anion resistance protein	A0A291I9K4	Lactobacillus_phage	2.3e-33	26.4
WP_010737126.1\|1147703_1148369_-\|lysis	5-bromo-4-chloroindolyl phosphate hydrolysis family protein	NA	NA	NA	NA
WP_010720827.1\|1148594_1149158_+	NUDIX hydrolase	NA	NA	NA	NA
WP_010720826.1\|1149170_1149455_+	hypothetical protein	NA	NA	NA	NA
WP_010737128.1\|1149471_1150164_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_081128460.1\|1150175_1150724_+	cysteine hydrolase	G3MA16	Bacillus_virus	5.2e-25	39.3

DBSCAN-SWA_84

1153870 : 1161315

Cafeteria_roenbergensis_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940921.1\|1153870_1155778_-	peptidase M13	E3T4I7	Cafeteria_roenbergensis_virus	1.4e-80	31.9
WP_164445096.1\|1155957_1156806_+	dihydrolipoamide dehydrogenase	NA	NA	NA	NA
WP_010720818.1\|1156887_1157862_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	1.7e-39	31.3
WP_094940923.1\|1158047_1159178_+	cysteine desulfurase	NA	NA	NA	NA
WP_010720816.1\|1159253_1159595_+	DUF1831 domain-containing protein	NA	NA	NA	NA
WP_010720815.1\|1159720_1160497_-	hypothetical protein	NA	NA	NA	NA
WP_034867759.1\|1160703_1161315_+	metallophosphoesterase family protein	A0A288TXW7	Enterococcus_phage	2.3e-34	41.5

DBSCAN-SWA_85

1179463 : 1185431

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720796.1\|1179463_1180099_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.1e-25	35.5
WP_010720795.1\|1180115_1180934_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010720794.1\|1181206_1182643_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	1.4e-50	30.7
WP_094940236.1\|1182989_1185431_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	9.5e-87	51.3

DBSCAN-SWA_86

1192609 : 1199593

Planktothrix_phage(20.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720785.1\|1192609_1193686_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.9e-19	29.6
WP_010720784.1\|1193660_1194617_+	ABC transporter ATP-binding protein	M1HRF1	Paramecium_bursaria_Chlorella_virus	5.5e-06	25.3
WP_094940089.1\|1194630_1195638_+	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	2.8e-53	40.2
WP_010737158.1\|1195949_1196771_-	NUDIX hydrolase	G3MA14	Bacillus_virus	6.6e-24	32.1
WP_094940090.1\|1197583_1199593_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	4.2e-96	38.0

DBSCAN-SWA_87

1203230 : 1206561

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940091.1\|1203230_1204304_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.0e-49	34.9
WP_053766321.1\|1204288_1204909_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.1e-30	39.3
WP_094940092.1\|1204905_1206081_+	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.6e-103	50.8
WP_010720773.1\|1206099_1206561_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.5e-38	60.0

DBSCAN-SWA_88

1213496 : 1214606

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720765.1\|1213496_1214606_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	Q6GZ03	Mycoplasma_phage	6.0e-20	34.6

DBSCAN-SWA_89

1219125 : 1222609

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737174.1\|1219125_1220892_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.3e-48	29.8
WP_094940098.1\|1220893_1222609_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.0e-51	29.1

DBSCAN-SWA_90

1230586 : 1232222

Apis_mellifera_filamentous_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737181.1\|1230586_1231231_-	lytic polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	5.2e-16	34.8
WP_010737182.1\|1231574_1232222_-	lytic polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	1.8e-13	33.0

DBSCAN-SWA_91

1236790 : 1237660

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737186.1\|1236790_1237660_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.9e-77	51.9

DBSCAN-SWA_92

1256228 : 1256675

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720730.1\|1256228_1256675_+	type II toxin-antitoxin system HicB family antitoxin	A0A1X9I727	Streptococcus_phage	1.6e-24	41.8

DBSCAN-SWA_93

1264573 : 1267114

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010720723.1\|1264573_1265083_-	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	3.7e-41	58.6
WP_034700569.1\|1265203_1266202_-	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	1.6e-27	50.0
WP_010720721.1\|1266529_1267114_+	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	3.8e-26	45.5

DBSCAN-SWA_94

1276784 : 1278113

Phaeocystis_globosa_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940239.1\|1276784_1278113_+	C1 family peptidase	R4TV59	Phaeocystis_globosa_virus	2.1e-72	35.0

DBSCAN-SWA_95

1283178 : 1283709

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081128178.1\|1283178_1283709_+	HAD family hydrolase	A0A0H3UZF4	Geobacillus_virus	5.7e-29	43.9

DBSCAN-SWA_96

1293340 : 1305220

Bacillus_phage(40.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718728.1\|1293340_1295986_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	1.0e-158	42.5
WP_094940245.1\|1296201_1297515_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_010718726.1\|1297504_1298161_+	HAD family phosphatase	M1I5S4	Acanthocystis_turfacea_Chlorella_virus	2.6e-07	25.6
WP_034698946.1\|1298218_1298911_+	DNA repair protein RadC	NA	NA	NA	NA
WP_010718724.1\|1299074_1299275_+	cold-shock protein	Q9AZD3	Lactococcus_phage	8.2e-21	71.2
WP_010718723.1\|1299440_1301123_-	ribonuclease J	NA	NA	NA	NA
WP_010718722.1\|1301124_1301337_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_094940246.1\|1301726_1303457_+	multidrug efflux ABC transporter subunit EfrA	W8CYL7	Bacillus_phage	3.5e-43	28.2
WP_010718720.1\|1303453_1305220_+	multidrug efflux ABC transporter subunit EfrB	W8CYL7	Bacillus_phage	6.1e-51	28.5

DBSCAN-SWA_97

1310285 : 1321188

Agrobacterium_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718717.1\|1310285_1310879_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	4.0e-55	56.1
WP_010718716.1\|1311057_1311585_+	hypothetical protein	NA	NA	NA	NA
WP_094940535.1\|1312055_1312790_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	4.4e-11	39.0
WP_095454171.1\|1312797_1313724_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_034698955.1\|1313713_1314946_+	GTPase HflX	NA	NA	NA	NA
WP_010738058.1\|1315150_1315543_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_094940534.1\|1315573_1316914_+	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	7.7e-06	36.4
WP_094941003.1\|1318025_1319249_+	hypothetical protein	NA	NA	NA	NA
WP_010718709.1\|1319577_1321188_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.3e-145	48.9

DBSCAN-SWA_98

1340506 : 1348342

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940529.1\|1340506_1342255_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	9.3e-52	41.9
WP_010718691.1\|1342279_1342591_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_010718690.1\|1342614_1343211_+	recombination protein RecR	NA	NA	NA	NA
WP_010718689.1\|1343274_1343919_+	dTMP kinase	M1PSC7	Streptococcus_phage	3.5e-57	52.2
WP_010718688.1\|1343933_1344263_+	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_010718687.1\|1344271_1345213_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.4e-32	32.3
WP_010738041.1\|1345248_1346073_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_010718685.1\|1346065_1346410_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-18	41.4
WP_094940528.1\|1347070_1347937_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-90	62.7
WP_002328071.1\|1348081_1348342_+	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	6.9e-12	52.6

DBSCAN-SWA_99

1358644 : 1362174

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718671.1\|1358644_1360450_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.6e-51	31.4
WP_094940522.1\|1360446_1362174_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.1e-40	27.8

DBSCAN-SWA_100

1376092 : 1376764

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718656.1\|1376092_1376764_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-35	39.1

DBSCAN-SWA_101

1380740 : 1393686

Tupanvirus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454175.1\|1380740_1383053_+	chitinase	A0A2K9L3D4	Tupanvirus	1.0e-34	29.1
WP_094940514.1\|1383316_1384231_-	ribonuclease HIII	NA	NA	NA	NA
WP_010718651.1\|1384452_1384890_+	cell division protein ZapA	NA	NA	NA	NA
WP_095454176.1\|1384911_1385460_+	CvpA family protein	NA	NA	NA	NA
WP_010718649.1\|1385589_1387950_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	3.8e-24	50.4
WP_010718648.1\|1388035_1388350_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	6.2e-15	40.8
WP_010738020.1\|1388545_1390324_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_010718646.1\|1390661_1391561_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-23	29.6
WP_010738019.1\|1391553_1392816_+	ABC transporter permease	NA	NA	NA	NA
WP_010718644.1\|1392966_1393686_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A0R6CN44	Citrobacter_phage	3.5e-05	36.0

DBSCAN-SWA_102

1406227 : 1407598

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010738007.1\|1406227_1407598_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	3.6e-27	31.1

DBSCAN-SWA_103

1424797 : 1426096

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718611.1\|1424797_1426096_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	4.8e-194	81.5

DBSCAN-SWA_104

1433515 : 1436386

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_105198796.1\|1433515_1435882_+	ribonuclease R	Q0GXV6	Lactococcus_phage	5.2e-98	42.2
WP_010718601.1\|1435921_1436386_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.0e-45	59.9

DBSCAN-SWA_105

1448477 : 1452754

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718585.1\|1448477_1448747_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	4.5e-22	57.3
WP_094940500.1\|1448733_1449231_+	GNAT family N-acetyltransferase	E9LUK4	Lactobacillus_phage	4.1e-13	33.6
WP_095454333.1\|1449311_1450199_+	ROK family protein	NA	NA	NA	NA
WP_010718582.1\|1450282_1450516_+	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_010718581.1\|1450882_1451053_+	hypothetical protein	NA	NA	NA	NA
WP_010718580.1\|1451309_1452017_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_094940499.1\|1452112_1452754_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	8.1e-46	50.3

DBSCAN-SWA_106

1460611 : 1461298

Pithovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718569.1\|1460611_1461298_+	cell division ATP-binding protein FtsE	W5SAS9	Pithovirus	3.0e-14	27.3

DBSCAN-SWA_107

1467110 : 1468691

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718563.1\|1467110_1467917_+	phosphate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.6e-14	27.9
WP_010718562.1\|1467932_1468691_+	phosphate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.7e-16	28.8

DBSCAN-SWA_108

1476028 : 1476967

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718553.1\|1476028_1476967_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	3.2e-75	51.4

DBSCAN-SWA_109

1489364 : 1496265

Bodo_saltans_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940338.1\|1489364_1490264_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	9.7e-21	29.6
WP_010718543.1\|1490521_1492099_-	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_010718542.1\|1492337_1492562_+	YneF family protein	NA	NA	NA	NA
WP_095454186.1\|1492736_1494497_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.2e-51	30.0
WP_095454187.1\|1494486_1496265_+	ABC transporter ATP-binding protein	A0A076FI99	Aureococcus_anophage	4.3e-20	25.2

DBSCAN-SWA_110

1500944 : 1508489

Bacillus_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718536.1\|1500944_1501874_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.5e-85	51.5
WP_094940342.1\|1502068_1502464_+	hypothetical protein	NA	NA	NA	NA
WP_010737954.1\|1502601_1504329_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.5e-206	62.9
WP_025480128.1\|1504343_1504691_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_010718532.1\|1504842_1505700_-	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_010718531.1\|1505792_1506221_+	transcriptional repressor	NA	NA	NA	NA
WP_010718530.1\|1506386_1506584_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_010718529.1\|1506610_1507057_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	5.9e-19	37.4
WP_010718528.1\|1507517_1508489_+	PhoH family protein	H6X2N1	Pseudomonas_phage	3.5e-48	47.2

DBSCAN-SWA_111

1518480 : 1526843

Streptococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940344.1\|1518480_1519176_+	CpsD/CapB family tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	2.0e-26	37.7
WP_010737946.1\|1519195_1519960_+	tyrosine protein phosphatase	NA	NA	NA	NA
WP_010718517.1\|1519971_1521789_+	polysaccharide biosynthesis protein	A0A2P1ELS8	Moumouvirus	2.0e-25	29.3
WP_063627379.1\|1521957_1522587_+	acetyltransferase	NA	NA	NA	NA
WP_192574430.1\|1522624_1523707_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A2K9L0G1	Tupanvirus	2.1e-30	27.7
WP_094940346.1\|1523699_1524326_+	sugar transferase	NA	NA	NA	NA
WP_094940347.1\|1524337_1525429_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_094940348.1\|1525673_1526843_+	nucleotide sugar dehydrogenase	M1HV26	Paramecium_bursaria_Chlorella_virus	5.2e-99	47.5

DBSCAN-SWA_112

1532575 : 1533868

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940349.1\|1532575_1533868_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	1.2e-43	32.7

DBSCAN-SWA_113

1538768 : 1545178

Lactococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005875554.1\|1538768_1538969_+	cold-shock protein	Q9AZD3	Lactococcus_phage	5.7e-22	72.7
WP_095454190.1\|1539253_1542034_+	DEAD/DEAH box helicase family protein	A0A1X9I5C8	Streptococcus_phage	1.4e-62	36.1
WP_094940352.1\|1542111_1542633_+	DUF5590 domain-containing protein	NA	NA	NA	NA
WP_034700871.1\|1542652_1543843_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_094940353.1\|1543879_1545178_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	6.2e-61	30.5

DBSCAN-SWA_114

1548607 : 1550668

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940356.1\|1548607_1550668_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.5e-114	35.7

DBSCAN-SWA_115

1554029 : 1558479

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940358.1\|1554029_1556213_+	copper-translocating P-type ATPase CopA	A0A218MNH6	uncultured_virus	3.0e-116	37.8
WP_094940359.1\|1556241_1558479_+	copper/silver-translocating P-type ATPase CopB	A0A218MNH6	uncultured_virus	2.8e-69	31.7

DBSCAN-SWA_116

1564640 : 1569640

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940362.1\|1564640_1567106_+	cation-translocating P-type ATPase	M1HRW9	Paramecium_bursaria_Chlorella_virus	9.7e-47	26.6
WP_094940363.1\|1567205_1568939_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	1.1e-31	34.8
WP_010718479.1\|1568935_1569640_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-38	37.1

DBSCAN-SWA_117

1573700 : 1575693

Lactobacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940365.1\|1573700_1574255_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	4.3e-11	29.8
WP_094940366.1\|1574593_1574794_+	PLDc N-terminal domain-containing protein	NA	NA	NA	NA
WP_094940367.1\|1574793_1575693_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.5e-32	35.8

DBSCAN-SWA_118

1590800 : 1592234

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034700815.1\|1590800_1592234_+	6-phospho-beta-galactosidase	A0A0B5JD41	Pandoravirus	5.5e-50	28.3

DBSCAN-SWA_119

1596190 : 1598221

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940372.1\|1596190_1598221_+	potassium-transporting ATPase subunit KdpB	M1HBF8	Paramecium_bursaria_Chlorella_virus	1.7e-28	26.1

DBSCAN-SWA_120

1601445 : 1602132

Bacillus_thuringiensis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718443.1\|1601445_1602132_+	response regulator transcription factor	Q56AR1	Bacillus_thuringiensis_phage	4.4e-05	31.6

DBSCAN-SWA_121

1626814 : 1676953

Enterococcus_phage(30.43%)

integrase,portal,tRNA,capsid,terminase,tail

attL 1635891:1635912|attR 1682366:1682387

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718417.1\|1626814_1627531_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-33	36.2
WP_010718416.1\|1627530_1628973_+	HAMP domain-containing histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	5.9e-20	31.3
WP_010718415.1\|1629247_1629754_-	hypothetical protein	NA	NA	NA	NA
WP_010737848.1\|1629740_1630469_-	hypothetical protein	NA	NA	NA	NA
WP_010718413.1\|1630797_1632939_-	LTA synthase family protein	W6LM83	Streptococcus_phage	9.9e-213	56.1
WP_094940376.1\|1633168_1634341_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.1e-104	52.6
WP_010737845.1\|1634354_1635104_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	4.2e-25	35.2
WP_025480513.1\|1635130_1635616_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
1635891:1635912	attL	NA	NA	NA	NA
WP_094940413.1\|1636297_1637551_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	1.1e-22	53.8
WP_010718408.1\|1637664_1639014_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_010718407.1\|1639127_1640474_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_053766637.1\|1640575_1641799_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	5.3e-78	41.8
WP_053766638.1\|1641953_1643018_-	type I restriction enzyme HsdR N-terminal domain-containing protein	A0A1S5SAB0	Streptococcus_phage	2.0e-110	56.0
WP_010718404.1\|1643075_1643504_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_053766639.1\|1643510_1643885_-	helix-turn-helix transcriptional regulator	O03970	Lactobacillus_phage	3.1e-21	42.4
WP_053766640.1\|1644044_1644284_+	helix-turn-helix transcriptional regulator	Q0H243	Geobacillus_phage	1.5e-13	58.2
WP_053766642.1\|1644805_1645360_+	hypothetical protein	NA	NA	NA	NA
WP_010718399.1\|1645356_1645587_+	DNA-binding protein	NA	NA	NA	NA
WP_010718398.1\|1645603_1645789_+	hypothetical protein	NA	NA	NA	NA
WP_010718397.1\|1645829_1646075_+	hypothetical protein	NA	NA	NA	NA
WP_053766643.1\|1646146_1647088_+	YqaJ viral recombinase family protein	D2IZK1	Enterococcus_phage	7.3e-128	70.9
WP_095454197.1\|1647089_1647965_+	recombinase RecT	D2IYT9	Enterococcus_phage	3.8e-86	58.0
WP_053766645.1\|1648004_1648883_+	DUF4373 domain-containing protein	D2IZY0	Enterococcus_phage	3.6e-68	50.3
WP_053766646.1\|1648898_1649228_+	hypothetical protein	NA	NA	NA	NA
WP_053766647.1\|1649228_1649423_+	hypothetical protein	NA	NA	NA	NA
WP_053766648.1\|1649440_1649728_+	hypothetical protein	NA	NA	NA	NA
WP_053766649.1\|1649693_1649930_+	hypothetical protein	NA	NA	NA	NA
WP_053766650.1\|1650356_1650755_+	hypothetical protein	C9E2P5	Enterococcus_phage	2.0e-26	46.7
WP_053766651.1\|1651191_1651332_-	rubredoxin-like protein	NA	NA	NA	NA
WP_053766652.1\|1652016_1652742_+	hypothetical protein	NA	NA	NA	NA
WP_053766653.1\|1652788_1653634_+\|terminase	small subunit of terminase	C9E2I6	Enterococcus_phage	2.5e-79	64.3
WP_053766654.1\|1653623_1655039_+	DEAD/DEAH box helicase family protein	C9E2I7	Enterococcus_phage	3.6e-219	79.7
WP_053766655.1\|1655050_1656580_+\|portal	phage portal protein	A0A0S2MVB2	Bacillus_phage	3.0e-30	25.8
WP_053766856.1\|1656671_1657550_+\|capsid	minor capsid protein	NA	NA	NA	NA
WP_053766656.1\|1657551_1657869_+	hypothetical protein	NA	NA	NA	NA
WP_053766657.1\|1658014_1658713_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_034867678.1\|1658726_1659617_+	DUF5309 domain-containing protein	NA	NA	NA	NA
WP_002311614.1\|1659639_1659855_+	hypothetical protein	NA	NA	NA	NA
WP_095454201.1\|1659866_1660208_+	hypothetical protein	NA	NA	NA	NA
WP_034867685.1\|1660207_1660579_+	hypothetical protein	NA	NA	NA	NA
WP_053766659.1\|1660571_1660967_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_053766660.1\|1660968_1661346_+	hypothetical protein	NA	NA	NA	NA
WP_034867690.1\|1661346_1661964_+\|tail	tail protein	NA	NA	NA	NA
WP_034698427.1\|1661963_1662305_+	hypothetical protein	NA	NA	NA	NA
WP_053766857.1\|1662546_1665336_+	tape measure protein	D7RWD8	Brochothrix_phage	6.0e-69	40.5
WP_053766661.1\|1665325_1666066_+\|tail	phage tail protein	NA	NA	NA	NA
WP_053766662.1\|1666062_1668774_+	peptidoglycan DD-metalloendopeptidase family protein	Q9AZX5	Lactococcus_phage	8.6e-214	44.1
WP_053766663.1\|1668790_1671205_+	hypothetical protein	A0A1S5SAM8	Streptococcus_phage	1.9e-10	46.3
WP_053766664.1\|1671344_1671689_+	hypothetical protein	A0A0P0IZF9	Lactobacillus_phage	1.7e-13	40.4
WP_053766665.1\|1671685_1671976_+	hypothetical protein	NA	NA	NA	NA
WP_095454202.1\|1671972_1673004_+	glycosyl hydrolase family 25	F0PIJ7	Enterococcus_phage	5.7e-33	38.6
WP_053766667.1\|1673178_1673700_-	hypothetical protein	NA	NA	NA	NA
WP_053766668.1\|1673905_1674472_-	hypothetical protein	NA	NA	NA	NA
WP_192574425.1\|1674894_1675326_+	DUF4231 domain-containing protein	NA	NA	NA	NA
WP_002295273.1\|1675558_1675816_-	hypothetical protein	NA	NA	NA	NA
WP_002287105.1\|1675978_1676953_+	choloylglycine hydrolase family protein	M1HVK5	Paramecium_bursaria_Chlorella_virus	5.4e-25	31.8
1682366:1682387	attR	NA	NA	NA	NA

DBSCAN-SWA_122

1687094 : 1689586

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034698405.1\|1687094_1688897_-	glycerophosphoryl diester phosphodiesterase membrane domain-containing protein	A0A173GBD0	Staphylococcus_phage	2.2e-11	27.6
WP_010737813.1\|1688989_1689586_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	4.3e-33	41.7

DBSCAN-SWA_123

1693351 : 1701835

Oenococcus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454204.1\|1693351_1694716_+	hypothetical protein	V9QKK6	Oenococcus_phage	4.6e-06	22.1
WP_010718832.1\|1694794_1695742_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	6.1e-82	50.2
WP_094940620.1\|1696331_1698227_+	asparagine synthase (glutamine-hydrolyzing)	F2Y2L7	Organic_Lake_phycodnavirus	3.2e-21	25.8
WP_010718834.1\|1698334_1698781_-	DUF2188 domain-containing protein	NA	NA	NA	NA
WP_002296119.1\|1699002_1699152_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_010737807.1\|1699320_1699824_+	dihydrofolate reductase	A0A076GDN3	Bacillus_phage	7.9e-20	38.6
WP_010718836.1\|1699902_1700859_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_172595703.1\|1701001_1701835_+	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	2.5e-15	31.2

DBSCAN-SWA_124

1711039 : 1717419

Tupanvirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034698360.1\|1711039_1712029_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	1.8e-52	37.9
WP_053766732.1\|1712036_1713521_+	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_010718851.1\|1713559_1714540_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	4.9e-18	28.0
WP_010737794.1\|1714671_1715394_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_010737793.1\|1715377_1715917_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_010737792.1\|1715926_1716394_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_094940616.1\|1716390_1717419_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	8.4e-61	41.1

DBSCAN-SWA_125

1721106 : 1725827

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025480509.1\|1721106_1721775_+	CpsD/CapB family tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	2.9e-22	36.1
WP_095454206.1\|1721856_1723686_+	polysaccharide biosynthesis protein	A0A2P1ELS8	Moumouvirus	6.6e-24	29.3
WP_034698344.1\|1723765_1725046_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_094940615.1\|1725038_1725827_+	glycosyltransferase family 2 protein	A0A0F7L2F7	uncultured_marine_virus	4.5e-06	32.1

DBSCAN-SWA_126

1730916 : 1732608

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034698338.1\|1730916_1732608_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	9.0e-76	33.4

DBSCAN-SWA_127

1737120 : 1753822

Flavobacterium_phage(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718874.1\|1737120_1737930_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	2.0e-25	46.0
WP_095454208.1\|1737926_1738727_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_094940614.1\|1739111_1740380_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_010718877.1\|1740449_1742153_+\|tRNA	proline--tRNA ligase	A0A2K9L6B6	Tupanvirus	5.2e-07	24.1
WP_053766742.1\|1742350_1743145_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	9.2e-07	25.0
WP_094940613.1\|1743161_1744004_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.4e-66	47.2
WP_010737776.1\|1744135_1744501_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_034698557.1\|1744651_1749004_+	PolC-type DNA polymerase III	A0A0A8WJ41	Clostridium_phage	2.7e-23	39.5
WP_010718882.1\|1749147_1749621_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_010718883.1\|1749642_1750830_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_010718884.1\|1750853_1751147_+	YlxR family protein	NA	NA	NA	NA
WP_010718885.1\|1751143_1751455_+	YlxQ-related RNA-binding protein	NA	NA	NA	NA
WP_053766744.1\|1751467_1753822_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.5e-20	24.0

DBSCAN-SWA_128

1756912 : 1757698

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034698325.1\|1756912_1757698_+	glucose-1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	1.9e-20	30.1

DBSCAN-SWA_129

1773086 : 1774604

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737757.1\|1773086_1774604_+	response regulator	W8CYM9	Bacillus_phage	1.0e-09	27.9

DBSCAN-SWA_130

1784898 : 1785960

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940603.1\|1784898_1785960_+	family 20 glycosylhydrolase	A0A076G5S5	Staphylococcus_phage	1.8e-26	25.5

DBSCAN-SWA_131

1793600 : 1804672

Chrysochromulina_ericina_virus(40.0%)

integrase

attL 1781895:1781912|attR 1799568:1799585

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1781895:1781912	attL	NA	NA	NA	NA
WP_094940586.1\|1793600_1794980_+\|integrase	tyrosine-type recombinase/integrase	A0A068A216	Staphylococcus_phage	5.0e-24	26.8
WP_094940585.1\|1795069_1796236_+	oxygen-independent coproporphyrinogen III oxidase	A0A0N7G7K6	Chrysochromulina_ericina_virus	7.2e-08	31.9
WP_010718939.1\|1796482_1797526_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_010718940.1\|1797571_1798135_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_010718941.1\|1798176_1800009_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	6.8e-138	49.0
1799568:1799585	attR	NA	NA	NA	NA
WP_010718942.1\|1800671_1801838_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	4.5e-26	29.0
WP_010718943.1\|1803934_1804672_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.1e-33	40.6

DBSCAN-SWA_132

1808561 : 1816628

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737739.1\|1808561_1811399_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.6e-311	56.7
WP_010718947.1\|1811636_1812902_+	D-aspartate ligase	NA	NA	NA	NA
WP_094940109.1\|1812905_1813625_+	amino acid racemase	NA	NA	NA	NA
WP_010718949.1\|1813778_1814663_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	31.4
WP_010718950.1\|1814659_1815658_+	YvcK family protein	A1IMD5	Streptococcus_phage	5.2e-116	63.6
WP_010718951.1\|1815692_1816628_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.7e-52	38.8

DBSCAN-SWA_133

1828530 : 1835841

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718960.1\|1828530_1829889_+	phosphoglucosamine mutase	A0A127AWJ1	Bacillus_phage	1.4e-18	25.7
WP_095454335.1\|1832301_1834110_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	2.1e-94	38.2
WP_010737730.1\|1834509_1834800_+	hypothetical protein	NA	NA	NA	NA
WP_010718964.1\|1834812_1835841_+	signal peptide peptidase SppA	A0A2I6UH21	Salinibacter_virus	1.0e-21	30.0

DBSCAN-SWA_134

1839165 : 1840416

Bacillus_virus(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718968.1\|1839165_1840416_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.7e-143	62.3

DBSCAN-SWA_135

1852887 : 1857172

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063627213.1\|1852887_1855125_+	DNA helicase PcrA	A7KV33	Bacillus_phage	6.2e-125	40.0
WP_094940120.1\|1855141_1857172_+	NAD-dependent DNA ligase LigA	A0A289ZTZ3	Serratia_phage	5.9e-98	36.6

DBSCAN-SWA_136

1860494 : 1863241

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010718986.1\|1860494_1861535_+	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	7.1e-15	27.4
WP_094940121.1\|1861867_1863241_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A1X9I6F4	Streptococcus_phage	1.6e-136	52.8

DBSCAN-SWA_137

1869904 : 1873428

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940125.1\|1869904_1871692_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.7e-54	32.5
WP_094940126.1\|1871688_1873428_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.6e-33	27.1

DBSCAN-SWA_138

1880866 : 1882579

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081204092.1\|1880866_1882579_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	3.3e-17	27.3

DBSCAN-SWA_139

1897966 : 1899331

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940135.1\|1897966_1899331_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	9.8e-49	28.3

DBSCAN-SWA_140

1910979 : 1911711

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719028.1\|1910979_1911711_+	serine/threonine protein phosphatase	A7KV25	Bacillus_phage	9.4e-14	29.2

DBSCAN-SWA_141

1918458 : 1922010

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940143.1\|1918458_1921104_+	DNA polymerase I	F8WQ35	Bacillus_phage	4.7e-55	33.7
WP_095454229.1\|1921173_1922010_+	DNA-formamidopyrimidine glycosylase	A0A127AWE5	Bacillus_phage	3.2e-18	27.8

DBSCAN-SWA_142

1925360 : 1926287

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940148.1\|1925360_1926287_+	primosomal protein DnaI	S5MU12	Brevibacillus_phage	5.7e-32	39.7

DBSCAN-SWA_143

1933013 : 1940475

Vibrio_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940150.1\|1933013_1935626_+	ATP-dependent chaperone ClpB	A0A2I7SAX5	Vibrio_phage	3.0e-131	34.9
WP_010719050.1\|1936103_1936769_-	hypothetical protein	NA	NA	NA	NA
WP_010719051.1\|1936761_1937256_-	nucleoside 2-deoxyribosyltransferase	A0A1W6JK28	Lactococcus_phage	7.2e-42	60.7
WP_094940151.1\|1937272_1938493_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_010719053.1\|1938639_1940475_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	2.0e-20	24.4

DBSCAN-SWA_144

1953210 : 1957618

Listeria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719068.1\|1953210_1953813_-	DUF4352 domain-containing protein	A8ASM1	Listeria_phage	1.8e-18	45.2
WP_010719069.1\|1954256_1954643_+	YxeA family protein	NA	NA	NA	NA
WP_010719071.1\|1955982_1956132_-	hypothetical protein	NA	NA	NA	NA
WP_010719072.1\|1956477_1956678_+	cold-shock protein	Q9AZD3	Lactococcus_phage	4.6e-24	80.0
WP_034698126.1\|1956953_1957340_-	hypothetical protein	NA	NA	NA	NA
WP_063627160.1\|1957372_1957618_-	helix-turn-helix transcriptional regulator	A0A1L2JY18	Aeribacillus_phage	5.9e-05	37.7

DBSCAN-SWA_145

1963495 : 1964389

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719082.1\|1963495_1964389_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	3.1e-59	46.0

DBSCAN-SWA_146

1980056 : 1980803

Clostridioides_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940207.1\|1980056_1980803_+	response regulator transcription factor	A0A2R2ZGH8	Clostridioides_phage	8.9e-12	28.0

DBSCAN-SWA_147

1998112 : 1999651

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454234.1\|1998112_1999651_-	alkyl hydroperoxide reductase subunit F	G3MA85	Bacillus_virus	1.7e-36	32.6

DBSCAN-SWA_148

2003537 : 2004515

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940322.1\|2003537_2004515_-	choloylglycine hydrolase family protein	M1I458	Paramecium_bursaria_Chlorella_virus	9.6e-22	30.5

DBSCAN-SWA_149

2009500 : 2011027

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454236.1\|2009500_2011027_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.9e-65	32.7

DBSCAN-SWA_150

2023024 : 2024191

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719132.1\|2023024_2024191_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	2.9e-49	40.4

DBSCAN-SWA_151

2034643 : 2036539

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454239.1\|2034643_2036539_+	selenocysteine-specific translation elongation factor	A0A2K9L516	Tupanvirus	7.8e-20	26.7

DBSCAN-SWA_152

2040732 : 2049325

Planktothrix_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940303.1\|2040732_2041611_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.6e-22	34.2
WP_010719143.1\|2041603_2042257_+	ABC transporter permease	NA	NA	NA	NA
WP_094940302.1\|2042269_2043118_+	hypothetical protein	NA	NA	NA	NA
WP_094940301.1\|2043358_2043991_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_034697978.1\|2044066_2044999_+	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	2.5e-64	44.7
WP_094940300.1\|2045324_2046773_+	amidase	NA	NA	NA	NA
WP_010737586.1\|2047007_2047697_+	hypothetical protein	U5PU21	Bacillus_phage	7.0e-19	40.7
WP_094940299.1\|2047703_2048693_+	sce7725 family protein	NA	NA	NA	NA
WP_095454242.1\|2048767_2049325_-	guanylate kinase	S4W1R9	Pandoravirus	3.9e-12	36.6

DBSCAN-SWA_153

2059366 : 2064625

Staphylococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719160.1\|2059366_2060215_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	7.5e-15	36.2
WP_010719161.1\|2060373_2060853_+	hypothetical protein	NA	NA	NA	NA
WP_095454244.1\|2060874_2063109_+	AAA family ATPase	R4T8G7	Halovirus	6.4e-05	24.5
WP_094940087.1\|2063407_2064625_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	5.3e-78	42.2

DBSCAN-SWA_154

2074278 : 2074968

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454248.1\|2074278_2074968_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.1e-27	36.1

DBSCAN-SWA_155

2091047 : 2096717

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940274.1\|2091047_2093237_-	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	1.3e-122	51.2
WP_094940273.1\|2093501_2094689_-	LCP family protein	NA	NA	NA	NA
WP_094940272.1\|2094816_2095680_-	shikimate dehydrogenase	NA	NA	NA	NA
WP_034697918.1\|2095946_2096717_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.9e-09	27.3

DBSCAN-SWA_156

2099841 : 2101551

Micromonas_pusilla_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940270.1\|2099841_2101551_+	fibronectin/fibrinogen-binding protein	M4R040	Micromonas_pusilla_virus	3.7e-05	31.1

DBSCAN-SWA_157

2106306 : 2107029

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940264.1\|2106306_2107029_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	8.3e-23	30.8

DBSCAN-SWA_158

2119800 : 2124404

Halovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454260.1\|2119800_2120877_-	carbamoyl phosphate synthase small subunit	R4TGJ8	Halovirus	1.3e-59	36.2
WP_053766057.1\|2120882_2122163_-	dihydroorotase	NA	NA	NA	NA
WP_010719215.1\|2122181_2123108_-	aspartate carbamoyltransferase catalytic subunit	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.0e-25	31.8
WP_010719216.1\|2123120_2124404_-	uracil transporter	Q9KX94	Enterobacteria_phage	9.2e-65	36.9

DBSCAN-SWA_159

2131232 : 2131439

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719225.1\|2131232_2131439_+	cold shock domain-containing protein	Q9AZD3	Lactococcus_phage	3.4e-14	52.3

DBSCAN-SWA_160

2136266 : 2141184

Tupanvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940255.1\|2136266_2138909_-\|tRNA	alanine--tRNA ligase	A0A2K9L3D8	Tupanvirus	7.0e-67	35.5
WP_094940254.1\|2139272_2139704_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_094940253.1\|2139834_2141184_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.3e-50	31.4

DBSCAN-SWA_161

2145531 : 2147897

Emiliania_huxleyi_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034697827.1\|2145531_2146722_-	glycine C-acetyltransferase	D2TEZ5	Emiliania_huxleyi_virus	1.3e-49	32.6
WP_034697824.1\|2147210_2147897_-	HD domain-containing protein	A0A1D6Y7U0	Golden_Marseillevirus	5.5e-16	29.9

DBSCAN-SWA_162

2152348 : 2152996

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940248.1\|2152348_2152996_+	Holliday junction resolvase RecU	A0A2H4J3A4	uncultured_Caudovirales_phage	4.0e-24	37.9

DBSCAN-SWA_163

2156076 : 2156778

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034697809.1\|2156076_2156778_-	DnaD domain protein	A0A0N7AE27	Bacillus_phage	3.8e-12	36.3

DBSCAN-SWA_164

2161513 : 2170657

Bacillus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719255.1\|2161513_2162440_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.7e-113	66.7
WP_034697803.1\|2162576_2163437_-	glucosaminidase domain-containing protein	A0A0A7RUS8	Clostridium_phage	3.2e-13	39.9
WP_010737506.1\|2163711_2165706_-	transketolase	NA	NA	NA	NA
WP_010719258.1\|2165804_2166059_-	DUF896 family protein	NA	NA	NA	NA
WP_010719259.1\|2166207_2166831_+	transcriptional repressor LexA	A0A1B1P7Q3	Bacillus_phage	1.1e-15	60.3
WP_010719260.1\|2167338_2167557_+	hypothetical protein	NA	NA	NA	NA
WP_010719261.1\|2167833_2168346_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.6e-31	45.4
WP_094940435.1\|2168359_2170657_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.5e-81	34.7

DBSCAN-SWA_165

2181719 : 2182478

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719273.1\|2181719_2182478_+	peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	2.6e-22	38.7

DBSCAN-SWA_166

2187774 : 2189124

Cassava_brown_streak_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940926.1\|2187774_2189124_-	ribonuclease PH	C6K8R3	Cassava_brown_streak_virus	2.4e-15	33.7

DBSCAN-SWA_167

2201123 : 2203622

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454267.1\|2201123_2203622_-	vitamin B12-dependent ribonucleotide reductase	A0A0K2CP92	Brevibacillus_phage	8.6e-184	47.0

DBSCAN-SWA_168

2213096 : 2213834

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719300.1\|2213096_2213834_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.1e-33	39.5

DBSCAN-SWA_169

2217583 : 2223050

Orpheovirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940428.1\|2217583_2218627_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	7.8e-30	32.8
WP_010719304.1\|2218921_2219263_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_095454270.1\|2219333_2223050_-	helicase-exonuclease AddAB subunit AddA	S5MMD7	Bacillus_phage	1.6e-24	23.6

DBSCAN-SWA_170

2226987 : 2228454

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719307.1\|2226987_2228454_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.6e-89	39.0

DBSCAN-SWA_171

2240155 : 2240773

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737411.1\|2240155_2240773_+	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	2.5e-36	60.4

DBSCAN-SWA_172

2248679 : 2253137

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719334.1\|2248679_2249306_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	6.7e-53	52.0
WP_053766367.1\|2249333_2250038_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_010737464.1\|2250203_2251037_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_094940572.1\|2251217_2253137_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.6e-105	39.6

DBSCAN-SWA_173

2256419 : 2259165

Geobacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_105198808.1\|2256419_2258690_-	DNA internalization-related competence protein ComEC/Rec2	Q0H255	Geobacillus_phage	1.3e-29	35.3
WP_010719343.1\|2258682_2259165_-	ComE operon protein 2	A7KUY9	Bacillus_phage	9.8e-36	60.0

DBSCAN-SWA_174

2262360 : 2262852

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034700679.1\|2262360_2262852_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.4e-21	34.6

DBSCAN-SWA_175

2270525 : 2272277

Acanthamoeba_polyphaga_lentillevirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940579.1\|2270525_2272277_-	DNA helicase RecQ	J2YAJ8	Acanthamoeba_polyphaga_lentillevirus	6.4e-77	36.1

DBSCAN-SWA_176

2287000 : 2288407

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719369.1\|2287000_2288407_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.4e-45	28.1

DBSCAN-SWA_177

2294170 : 2295148

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719374.1\|2294170_2295148_-	GMP reductase	G3MBI2	Bacillus_virus	1.3e-148	79.8

DBSCAN-SWA_178

2298315 : 2310522

Prochlorococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454276.1\|2298315_2299851_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.3e-73	49.5
WP_010719379.1\|2299843_2300437_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.2e-24	34.6
WP_010719380.1\|2300433_2301477_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.1e-63	43.2
WP_034700370.1\|2301490_2302933_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-50	32.9
WP_095454277.1\|2302917_2305140_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.7e-147	41.3
WP_094940819.1\|2305141_2305813_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_010737437.1\|2305814_2306069_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_094940818.1\|2306083_2306800_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	1.7e-47	42.8
WP_010737435.1\|2307061_2307439_+	hypothetical protein	NA	NA	NA	NA
WP_010737434.1\|2307595_2308903_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	6.2e-16	27.3
WP_172595681.1\|2308916_2310041_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_010719389.1\|2310033_2310522_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	7.4e-23	44.7

DBSCAN-SWA_179

2316546 : 2317164

Clostridium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454278.1\|2316546_2317164_-	glycoside hydrolase family 73 protein	A0A0A7RUS8	Clostridium_phage	4.6e-22	41.3

DBSCAN-SWA_180

2323733 : 2326337

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940816.1\|2323733_2326337_-	HAD-IC family P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	1.2e-63	27.7

DBSCAN-SWA_181

2339343 : 2339961

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010737411.1\|2339343_2339961_+	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	2.5e-36	60.4

DBSCAN-SWA_182

2348390 : 2349356

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034700339.1\|2348390_2349356_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.1e-29	36.9

DBSCAN-SWA_183

2378953 : 2385946

Bacillus_virus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940797.1\|2378953_2381185_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.8e-169	42.4
WP_094940796.1\|2381459_2383910_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.5e-95	31.3
WP_010737383.1\|2383921_2385946_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	4.0e-115	41.6

DBSCAN-SWA_184

2389370 : 2397781

Erwinia_phage(25.0%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719460.1\|2389370_2390771_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	4.8e-43	29.5
WP_010719461.1\|2390783_2391332_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_010719462.1\|2391371_2392271_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	2.8e-36	30.7
WP_179287085.1\|2392553_2393927_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_010719464.1\|2393895_2395974_-	type I DNA topoisomerase	A0A2P1EID3	Megavirus	1.1e-96	37.2
WP_081128696.1\|2396094_2396952_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_094940794.1\|2397013_2397781_-	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	1.3e-26	42.7

DBSCAN-SWA_185

2405427 : 2409869

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719545.1\|2405427_2406270_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	3.5e-20	42.4
WP_010719546.1\|2406501_2406996_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	7.7e-28	41.0
WP_034700291.1\|2407015_2407963_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	4.5e-125	65.9
WP_094940791.1\|2407973_2409869_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.8e-51	29.7

DBSCAN-SWA_186

2415791 : 2418415

unidentified_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940789.1\|2415791_2417000_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	5.8e-45	51.5
WP_010719556.1\|2417026_2417380_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_010719557.1\|2417539_2418415_+	YitT family protein	M1Q1P6	Streptococcus_phage	1.3e-62	44.4

DBSCAN-SWA_187

2423856 : 2428142

Streptococcus_phage(33.33%)

integrase

attL 2417028:2417042|attR 2429396:2429410

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2417028:2417042	attL	NA	NA	NA	NA
WP_161298820.1\|2423856_2424303_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5S8R9	Streptococcus_phage	1.4e-23	41.1
WP_002290178.1\|2424533_2424809_-	HU family DNA-binding protein	A0A0H3UZA0	Geobacillus_virus	1.8e-26	69.7
WP_010719563.1\|2425053_2426364_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_095454282.1\|2427179_2428142_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	9.8e-19	24.9
2429396:2429410	attR	NA	NA	NA	NA

DBSCAN-SWA_188

2435911 : 2437303

Acanthamoeba_polyphaga_lentillevirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454284.1\|2435911_2437303_-	ATP-dependent DNA helicase RecQ	J2YAJ8	Acanthamoeba_polyphaga_lentillevirus	9.7e-60	35.5

DBSCAN-SWA_189

2445218 : 2447819

uncultured_Mediterranean_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719579.1\|2445218_2445794_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.5e-14	33.3
WP_025480477.1\|2445777_2446572_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.4e-09	33.9
WP_094940782.1\|2446541_2446913_-	N-acetyltransferase	NA	NA	NA	NA
WP_010719582.1\|2446931_2447819_-	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	1.1e-32	30.3

DBSCAN-SWA_190

2452247 : 2459457

Synechococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719586.1\|2452247_2453357_-	RNA polymerase sigma factor RpoD	F4YCU2	Synechococcus_phage	9.8e-39	38.9
WP_094940780.1\|2453380_2455222_-	DNA primase	A0A1S5RH70	Helicobacter_phage	3.2e-50	31.3
WP_179287097.1\|2455408_2457730_-	HAD-IC family P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	3.9e-37	25.1
WP_034700257.1\|2457897_2458758_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_053766455.1\|2458824_2459457_-	lysozyme family protein	A0A0N9SIT8	Bacillus_phage	6.9e-13	36.8

DBSCAN-SWA_191

2463097 : 2467747

Aureococcus_anophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719593.1\|2463097_2464285_-	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	4.6e-34	29.4
WP_010719595.1\|2464997_2465378_-	VOC family protein	NA	NA	NA	NA
WP_010719596.1\|2465719_2466724_-	nucleoid-associated protein	A0A090D855	Clostridium_phage	1.2e-11	24.0
WP_094940775.1\|2466895_2467747_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.4e-53	40.7

DBSCAN-SWA_192

2475835 : 2482479

Lonomia_obliqua_multiple_nucleopolyhedrovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454338.1\|2475835_2478013_-	enhancin	A0A126FC74	Lonomia_obliqua_multiple_nucleopolyhedrovirus	1.8e-28	25.9
WP_094940769.1\|2478699_2479428_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_095454288.1\|2479812_2482479_-	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	1.2e-85	30.4

DBSCAN-SWA_193

2525185 : 2526181

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719623.1\|2525185_2526181_-	2-hydroxyacid dehydrogenase	M1NSB9	Streptococcus_phage	1.8e-23	31.6

DBSCAN-SWA_194

2544211 : 2548003

Ectocarpus_siliculosus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719635.1\|2544211_2545711_-	HAMP domain-containing histidine kinase	Q8QNA2	Ectocarpus_siliculosus_virus	6.6e-06	31.7
WP_005875038.1\|2545707_2546394_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.7e-28	31.2
WP_010738115.1\|2546581_2548003_-	NADP-dependent phosphogluconate dehydrogenase	A0A1D7RI04	Synechococcus_phage	1.6e-33	31.9

DBSCAN-SWA_195

2553716 : 2560702

Streptomyces_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454297.1\|2553716_2557031_-	DNA polymerase III subunit alpha	A0A0K1Y906	Streptomyces_phage	6.8e-144	32.2
WP_010719643.1\|2557255_2557444_+	YjzD family protein	NA	NA	NA	NA
WP_010738119.1\|2557716_2558913_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_034700533.1\|2559265_2560702_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	8.5e-43	28.3

DBSCAN-SWA_196

2566645 : 2570999

Tupanvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034700539.1\|2566645_2568586_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.6e-113	36.8
WP_002287649.1\|2568912_2569092_-	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_094940887.1\|2569205_2570999_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.4e-71	30.3

DBSCAN-SWA_197

2581651 : 2582374

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014834755.1\|2581651_2582374_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.2e-34	40.5

DBSCAN-SWA_198

2595115 : 2595853

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454298.1\|2595115_2595853_-	3-oxoacyl-[acyl-carrier-protein] reductase	Q06VL0	Trichoplusia_ni_ascovirus	5.4e-17	30.4

DBSCAN-SWA_199

2603885 : 2612379

Hokovirus(25.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719684.1\|2603885_2605613_-	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	7.1e-20	35.4
WP_010719685.1\|2605612_2605879_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_034867873.1\|2606434_2608672_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	4.7e-125	39.2
WP_010719687.1\|2608875_2609196_+	DUF1827 family protein	NA	NA	NA	NA
WP_010719688.1\|2609295_2609469_-	hypothetical protein	NA	NA	NA	NA
WP_014834762.1\|2609617_2610715_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.1e-23	28.2
WP_010738143.1\|2610798_2612379_-	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	2.5e-32	27.3

DBSCAN-SWA_200

2623748 : 2628586

Erysipelothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940954.1\|2623748_2625146_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	4.2e-87	37.4
WP_034698910.1\|2625309_2625990_-	DUF697 domain-containing protein	NA	NA	NA	NA
WP_010719701.1\|2626376_2626955_-	lytic polysaccharide monooxygenase	A0A0K1Y848	Apis_mellifera_filamentous_virus	6.3e-13	31.9
WP_094940955.1\|2627032_2628586_-	fibronectin type III domain-containing protein	M1HAV4	Paramecium_bursaria_Chlorella_virus	5.2e-22	29.4

DBSCAN-SWA_201

2639129 : 2640062

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719711.1\|2639129_2639330_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.3e-18	67.7
WP_034867853.1\|2639453_2640062_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	2.7e-67	59.1

DBSCAN-SWA_202

2649947 : 2650892

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940980.1\|2649947_2650892_-	NAD-dependent epimerase/dehydratase family protein	A0A1V0SKV4	Klosneuvirus	1.6e-50	39.4

DBSCAN-SWA_203

2656142 : 2663985

uncultured_marine_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719729.1\|2656142_2657117_-	glycosyltransferase family 2 protein	A0A0F7L2F7	uncultured_marine_virus	2.8e-05	32.7
WP_010738171.1\|2657109_2658171_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_010719731.1\|2658180_2658882_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_094940978.1\|2659116_2661834_-	glycosyl hydrolase family 25	D6PSS2	Lactobacillus_phage	2.5e-27	28.0
WP_010719733.1\|2661846_2662692_-	LicD family protein	NA	NA	NA	NA
WP_094940977.1\|2662944_2663985_-	glycosyltransferase family 2 protein	A0A2P1ELT8	Moumouvirus	4.6e-06	22.9

DBSCAN-SWA_204

2669351 : 2670572

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719738.1\|2669351_2670572_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.3e-12	27.5

DBSCAN-SWA_205

2675181 : 2678715

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014834184.1\|2675181_2676030_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.0e-35	37.0
WP_010719743.1\|2676211_2677240_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.1e-68	42.6
WP_010719744.1\|2677261_2677834_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	2.4e-41	49.2
WP_010719745.1\|2677848_2678715_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	5.7e-103	62.5

DBSCAN-SWA_206

2695642 : 2696932

Diachasmimorpha_longicaudata_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940968.1\|2695642_2696932_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.3e-31	26.9

DBSCAN-SWA_207

2700155 : 2704697

Cyanophage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719769.1\|2700155_2701685_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	3.3e-77	36.5
WP_063626760.1\|2701904_2704697_-\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	8.1e-90	27.4

DBSCAN-SWA_208

2725937 : 2728124

Gordonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034698802.1\|2725937_2727278_-	exodeoxyribonuclease VII large subunit	A0A160DF99	Gordonia_phage	7.2e-28	33.0
WP_094940963.1\|2727278_2728124_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	5.2e-40	38.9

DBSCAN-SWA_209

2741739 : 2743359

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034698791.1\|2741739_2743359_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	3.4e-24	24.2

DBSCAN-SWA_210

2753509 : 2776434

Tupanvirus(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454305.1\|2753509_2754715_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	A0A125RNP0	Pseudomonas_phage	1.7e-20	28.7
WP_010719822.1\|2754711_2756229_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9L3I8	Tupanvirus	2.6e-42	27.2
WP_014834217.1\|2756239_2756389_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_081127888.1\|2756679_2758743_-	ABC transporter permease	NA	NA	NA	NA
WP_094940958.1\|2758732_2759500_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-31	36.1
WP_095454306.1\|2759871_2762061_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	6.6e-289	66.4
WP_010719826.1\|2762307_2762910_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	1.3e-50	55.8
WP_010719827.1\|2762983_2764090_-	DNA polymerase IV	NA	NA	NA	NA
WP_010719828.1\|2764284_2764941_-	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_034698765.1\|2765163_2767101_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.9e-62	33.4
WP_010738280.1\|2767219_2767927_-	hypothetical protein	NA	NA	NA	NA
WP_010719831.1\|2769942_2770602_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.5e-21	31.2
WP_095454307.1\|2770620_2772123_-	ABC transporter permease	NA	NA	NA	NA
WP_094940448.1\|2772264_2772939_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.3e-29	34.5
WP_094940449.1\|2772943_2774260_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_095454308.1\|2774637_2776434_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.8e-90	36.2

DBSCAN-SWA_211

2781660 : 2786736

Mycoplasma_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719842.1\|2781660_2782467_-	ABC transporter permease	Q6GZ02	Mycoplasma_phage	6.5e-16	27.6
WP_010719843.1\|2782480_2783566_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	6.2e-38	46.0
WP_010719844.1\|2783583_2784126_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_095454310.1\|2784366_2785356_+	acryloyl-CoA reductase	NA	NA	NA	NA
WP_094940455.1\|2785352_2786099_+	phosphopantothenate--cysteine ligase	NA	NA	NA	NA
WP_010719847.1\|2786184_2786736_+	phosphopantothenoylcysteine decarboxylase	A0A1V0S7W6	Shearwaterpox_virus	1.6e-29	40.8

DBSCAN-SWA_212

2790228 : 2791740

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095454311.1\|2790228_2791740_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	1.4e-51	30.8

DBSCAN-SWA_213

2796343 : 2797821

Cafeteria_roenbergensis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940460.1\|2796343_2797096_+	exodeoxyribonuclease III	E3T4M6	Cafeteria_roenbergensis_virus	8.3e-58	46.7
WP_010719861.1\|2797287_2797821_+	exonuclease	M1PFD8	Streptococcus_phage	2.1e-23	38.3

DBSCAN-SWA_214

2801593 : 2802274

Elephant_endotheliotropic_herpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010719867.1\|2801593_2802274_-	uracil-DNA glycosylase	U5U481	Elephant_endotheliotropic_herpesvirus	8.1e-44	46.6

DBSCAN-SWA_215

2808362 : 2809121

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010738309.1\|2808362_2809121_+	nicotinamide mononucleotide transporter	A0A2H4PB74	Lactobacillus_phage	4.3e-94	69.5

DBSCAN-SWA_216

2822581 : 2825549

Erysipelothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034699765.1\|2822581_2824078_-	Lsa family ABC-F type ribosomal protection protein	A0A2I4R674	Erysipelothrix_phage	1.5e-29	27.2
WP_094940469.1\|2824427_2825549_-	glycerate kinase	W6LM47	Streptococcus_phage	3.0e-19	31.5

DBSCAN-SWA_217

2840203 : 2841277

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094940475.1\|2840203_2841277_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.0e-29	35.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP023011

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection