CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022988	Lactobacillus delbrueckii subsp. lactis DSM 20072 chromosome, complete genome	5 crisprs	cas14k,cas14j,cas3,DEDDh,Cas14u_CAS-V,cas5,cas8c,cas7,cas1,cas2,DinG,c2c9_V-U4,csa3,WYL	4	7	17	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022988_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022988_1

284729-285280

TypeV

Consensus_repeat	Method
AAGAAGNCANCTAAGAAG	CRT

13 spacers

cas14j

The CRISPR arrays of NZ_CP022988_1

>merge|NZ_CP022988|1|284729-285280|CRT
AAGAAGTCAGCTAAGAAGAGCACTAAGAAGAGCACTAAGAAGGCTGCAAAGAAGTCAGCTAAGAAGAGCACTAAGAAGGCTGCAAAGAAGTCAGCTAAGAAGGCTGCAAAGAAGTCAACTAAGAAGGCTACCAAGAAGGTAGCTAAGAAGGATGCAAAGAAGGCAACCAAGAAGTCAACTAAGAAGGCTGCAAAGAAGGCAACCAAGAAGTCAACTAAGAAGGCTGCAAAGAAGGCAACCAAGAAGTCAACTAAGAAGGCTGCAAAGAAGGCAACCAAGAAGTCAACTAAGAAGGCTGCAAAGAAGGCAACCAAGAACACTAAGAAGGTAGCTAAGAGCACTAAGAAGGCAAACAAGAAGTCAACTAAGAAGGCTGCAAAGAAGGCAACCAAGAAGTCAACTAAGAAGGCTGCAAAGAAGGCAACCAAGAAGTCAACTAAGAAGGCTGCAAAGAAGGCAACCAAGAACACTAAGAAGGCAGCTAAGACTACTAAGAAGGCAGCTAAGGACACCAAGAAGGCAGCTAAGACTACCAAGAAGTCAACTAAGAAG

>NZ_CP022988|1|1|284729-285280|CRT
AAGAAGTCAGCTAAGAAG	AGCACTAAGAAGAGCACTAAGAAGGCTGCA
AAGAAGTCAGCTAAGAAG	AGCACTAAGAAGGCTGCA
AAGAAGTCAGCTAAGAAG	GCTGCAAAGAAGTCAACTAAGAAGGCTACC
AAGAAGGTAGCTAAGAAG	GATGCAAAGAAGGCAACC
AAGAAGTCAACTAAGAAG	GCTGCAAAGAAGGCAACC
AAGAAGTCAACTAAGAAG	GCTGCAAAGAAGGCAACC
AAGAAGTCAACTAAGAAG	GCTGCAAAGAAGGCAACC
AAGAAGTCAACTAAGAAG	GCTGCAAAGAAGGCAACCAAGAACACTAAGAAGGTAGCTAAGAGCACT
AAGAAGGCAAACAAGAAG	TCAACTAAGAAGGCTGCA
AAGAAGGCAACCAAGAAG	TCAACTAAGAAGGCTGCA
AAGAAGGCAACCAAGAAG	TCAACTAAGAAGGCTGCA
AAGAAGGCAACCAAGAAC	ACTAAGAAGGCAGCTAAGACTACT
AAGAAGGCAGCTAAGGAC	ACCAAGAAGGCAGCTAAGACTACC
AAGAAGTCAACTAAGAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022988.1\|WP_003616123.1\|274977_275952_+\|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl\|CDD\|224016
NZ_CP022988.1\|WP_003612761.1\|276804_277230_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP022988.1\|WP_003612769.1\|280325_281033_-\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NZ_CP022988.1\|WP_002879841.1\|283179_283365_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022988.1\|WP_129335739.1\|285605_285911_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238075
NZ_CP022988.1\|WP_003616128.1\|271091_272264_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|133381
NZ_CP022988.1\|WP_003616126.1\|273444_274329_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NZ_CP022988.1\|WP_095439215.1\|289742_291449_+\|transposase	cas14j	-	gnl\|CDD\|284650
NZ_CP022988.1\|WP_035182812.1\|293487_296742_+\|SLAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367086
NZ_CP022988.1\|WP_003616104.1\|288393_288705_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022988.1\|WP_035182824.1\|281246_283121_+\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|273919
NZ_CP022988.1\|WP_095439216.1\|291698_291944_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022988.1\|WP_095439214.1\|289105_289774_+\|IS607-family-transposase	unknown	unknown	gnl\|CDD\|239738
NZ_CP022988.1\|WP_003616107.1\|286769_287783_+\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NZ_CP022988.1\|WP_003616115.1\|278662_280315_-\|alpha,alpha-phosphotrehalase	unknown	unknown	gnl\|CDD\|274115
NZ_CP022988.1\|WP_003616125.1\|274355_274964_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl\|CDD\|376414
NZ_CP022988.1\|WP_003616127.1\|272387_273425_+\|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224013
NZ_CP022988.1\|WP_035182815.1\|292260_293148_-\|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl\|CDD\|372824
NZ_CP022988.1\|WP_003616108.1\|285900_286230_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|143635
NZ_CP022988.1\|WP_003616106.1\|287919_288288_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045

Protein	Function_ID	Function_description	E-value
NZ_CP022988.1\|WP_003616123.1\|274977_275952_+\|dTDP-4-dehydrorhamnose-reductase	gnl\|CDD\|224016	COG1091, RfbD, dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane].	4.48028e-96
NZ_CP022988.1\|WP_003612761.1\|276804_277230_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	6.63808e-88
NZ_CP022988.1\|WP_003612769.1\|280325_281033_-\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	7.71947e-87
NZ_CP022988.1\|WP_095439214.1\|289105_289774_+\|IS607-family-transposase	gnl\|CDD\|239738	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.	7.51778e-55
NZ_CP022988.1\|WP_129335739.1\|285605_285911_-\|hypothetical-protein	gnl\|CDD\|238075	cd00130, PAS, PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction.	0.000534058
NZ_CP022988.1\|WP_003616128.1\|271091_272264_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	4.20242e-37
NZ_CP022988.1\|WP_003616126.1\|273444_274329_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	3.18405e-173
NZ_CP022988.1\|WP_095439215.1\|289742_291449_+\|transposase	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	1.10783e-12
NZ_CP022988.1\|WP_035182812.1\|293487_296742_+\|SLAP-domain-containing-protein	gnl\|CDD\|367086	pfam02435, Glyco_hydro_68, Levansucrase/Invertase. This Pfam family consists of the glycosyl hydrolase 68 family, including several bacterial levansucrase enzymes, and invertase from zymomonas.	8.78327e-80
NZ_CP022988.1\|WP_035182824.1\|281246_283121_+\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|273919	TIGR01995, beta-glucosides_PTS_EIIBCA, PTS system, beta-glucoside-specific IIABC component. This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.	0
NZ_CP022988.1\|WP_003616107.1\|286769_287783_+\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	1.05921e-158
NZ_CP022988.1\|WP_003616115.1\|278662_280315_-\|alpha,alpha-phosphotrehalase	gnl\|CDD\|274115	TIGR02403, Trehalose-6-phosphate_hydrolase, alpha,alpha-phosphotrehalase. Trehalose is a glucose disaccharide that serves in many biological systems as a compatible solute for protection against hyperosmotic and thermal stress. This family describes trehalose-6-phosphate hydrolase, product of the treC (or treA) gene, which is often found together with a trehalose uptake transporter and a trehalose operon repressor.	0
NZ_CP022988.1\|WP_003616125.1\|274355_274964_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl\|CDD\|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	3.90584e-101
NZ_CP022988.1\|WP_003616127.1\|272387_273425_+\|dTDP-glucose-4,6-dehydratase	gnl\|CDD\|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP022988.1\|WP_035182815.1\|292260_293148_-\|DNA/RNA-non-specific-endonuclease	gnl\|CDD\|372824	pfam13930, Endonuclea_NS_2, DNA/RNA non-specific endonuclease.	3.99798e-50
NZ_CP022988.1\|WP_003616108.1\|285900_286230_-\|hypothetical-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	0.0019578
NZ_CP022988.1\|WP_003616106.1\|287919_288288_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.05887e-15

>NZ_CP022988.1|WP_002879841.1|283179_283365_-|hypothetical-protein
MQFTKQFEGTFAQVKEQIDKFVAEGGHIDAVITDHTGEKVTEDHTFGYKMRVIAICSEEES
>NZ_CP022988.1|WP_035182824.1|281246_283121_+|PTS-glucose-transporter-subunit-IIA
MAKKDYSGLAKTIIANVGGKENINSLIHCITRLRFYLKDESKANDEVLKETDGVIDVMHASGQYQVVIGNAVTQVYDAVMAELGGLPEGGEAAETAETKEDDGKNPVSKAFGNLIGFITGSMSPVVGVIAASGIIKGILALLTLPQLGALLNVKSTAYITVSAMADSAFYFLPILVGFAAAKKLNGDPIVAAVIGGVLTYPQLVTWGGQYKTMFSLGGFNFQFLNYTYSIFPMILAAWLAKKLEDWLRDHLPDYLQMIFTPMITILLVSAVTLMITGPVIQGVANGIADLINWVVSASGWIGGLLIGAFYQVLVIFGLHWGVVPLVAQQIAQSGQSSLNAIISVTMVSQGAAVLAVALKTKKKGTKTLGISAAVSAFCGVTEPAIYGINLRFKRVFISGLIGSAVGGLITGLMHGTMYGFTGSLIGFSSFFNPKNPSDLTSFYAFLLSSAAALVISFIVAWVWGYNDEMVADKKVEKKQRPGSEAKQKSETLTAPVAGKVIALSSVNDPVFSTGAMGEGFAVVPTEGVVKAPVDGEVAALFETGHAIGLKTTAGAEVLIHIGIDTVMLKGKGFNVKVAQGDLVKAGQTLIEFDLDGIKEAGYDPTVMTVVTDKHDVDIKLPSVE
>NZ_CP022988.1|WP_003612769.1|280325_281033_-|trehalose-operon-repressor
MTAKQDMITQDLAGKIRHGIYPPKSFLPSENELANLYGASRNTVRKSLEDLTSLGLIQKIKGKGSIVLDFSRLSFPISRITTFNELNQSLGLKAETKLLEIKEVKKVPDDFSCDNTEPFIKVKRLRIIDGEPDVLDVDYISTKYVKEISPSVAEHSLYDYFENELGLKISYAVKDVSVQTVSEELAKMLELDPDRKAVLVKSMVYLEDTSLFQLTASYHNPNRFRFIDFARRSKI
>NZ_CP022988.1|WP_003616115.1|278662_280315_-|alpha,alpha-phosphotrehalase
MQNLGQKVIYQIYPKSFYDANGDGIGDLRGIIEKIDYIKKLNVDMIWFNPFYVSPQNDNGYDIANYREIDPLFGTMADFEELQAKLADIGVGVMLDMVLNHCSTEHEWFKKALAGDEKYRKFFYLRPGKPDGSLPNNWQSKFGGPAWSKFGDTDLYYLHLYDSTQADLDWHNPEVRKELEDVVNFWRGKGVRGFRFDVINVTGKSEDLVDSTDPTEEKTLYTDTPVVHDYLKELNRTTFGQDEDSITVGEMSSTTIPNSVRYTNPKEKELSMVFTFHHLKVDYKDGEKWTKTPFDFMKLKGLLSSWQTGMTEGGGWNAVFWNNHDQPWALNRFGDPVHYREKSAEMLVATIYFLRGTPFIYQGEELGMVNPDYQSMDEYVDVECKNAYQELLDKGMSEDEAFAIIKAKSRDNSRVPMHWDDSKYAGFSQVKPWLLPTHQDEINVKKELAEGEIFAFYQKLIALRKQEAVISAGGFREILPDDQQVFAYVRELDGEKLVVFNNFYGKEAVISVPSDLQECGQILLDNYKRELICLPGELSLRPYESLAFRI
>NZ_CP022988.1|WP_003612761.1|276804_277230_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MNEKVDLKDRLTPMQYAVTQNAATEPPYTGEYDNFFEKGIYVDVVSGEALFSSLDKYDSGCGWPAFTKPLVKLTQRRDQSFGMERTEVRSRQADSHLGHVFTDGPLDKGGLRYCINSAALKFIPYDQLEEAGYGEYRQLFE
>NZ_CP022988.1|WP_003616123.1|274977_275952_+|dTDP-4-dehydrorhamnose-reductase
MKVFVTGVNGQLGHDVMNELAKRGYEGVGSDLAPEYSGLADGSSVTTAPYVSLDITNAEGVKQAITEVNPDVIVHCAAWTAVELAEDDDKVAAVRKVNTDGTQNIANVAKELDVPMVYISTDYVFDGQGTTPWDPDFKGYKPMNVYGETKLGGELAVSETLDKYFIVRIAWVFGLNGKNFIKTMLNVGKTHDEVKVVSDQIGTPTYTLDLARLLVDMIETDKYGYYHATNAELPETASGYDENGTKTGYISWYDFTKEIYRQAGYKTKVTPVTTEEYGLSKAVRPFNSRLDKSKLEKNGFKPLPTWPDAVHRYLEALKAAGFFD
>NZ_CP022988.1|WP_003616125.1|274355_274964_+|dTDP-4-dehydrorhamnose-3,5-epimerase
MGQIKVEKNVGGIEGLAVITPAVHGDDRGYFMETYNENDMKEAGFDINFVQDNQSSSTKGVLRGLHFQKHFPQCKLVRAVRGDVFDVAVDLRSDSKTYGKWYGVELTAENKKQFLIPEGFAHGFLVLSDVAEFCYKVNDFWHPNDEGGMAWNDPEIGIEWPQLVGEYPGSADASGYALEDGTKLTLSDRDQKWLGLKDTFKF
>NZ_CP022988.1|WP_003616126.1|273444_274329_+|glucose-1-phosphate-thymidylyltransferase-RfbA
MKGIILAGGSGTRLYPLTLVTSKQLLPVYDKPMIYYPLSTLMLAGIKDILVISTPADTPRFKELLGDGSQFGVKLSYKVQPSPDGLAQAFTLGEDFINGEPCAMVLGDNIFYGNGFTDMLENAAKDAEAGRATIFGYYVNDPERFGVVEFDKDGHAISIEEKPAQPKSNYAVTGLYFYPAGVSERAAQVKPSARGEVEITSLNEMYLNDNTLDVQLLGRGYDWLDTGTMQSLVDASNFVKMVEERTGVSISAPEEIAYVHGWIDEDKLMEAAKHYGKSPYGQHLKAVAEGKLKY
>NZ_CP022988.1|WP_003616127.1|272387_273425_+|dTDP-glucose-4,6-dehydratase
MKIIVTGGAGFIGSNFVFYMMKKHPDYKIICLDKLTYAGNLSTLKDVMDKPNFRFVKLDICDREGVYKLFEEEHPDVVVNFAAESHVDRSIENPEIFLQTNIIGTSVLMDACRKYGIKRYHQVSTDEVYGDLSLDRPDLFFHEDTPLHTSSPYSSSKASADLLVGAYGRTYGLPVTISRCSNNYGPYQFPEKLIPLMIQRALDDKPLPVYGEGQNVRDWLYVEDHCKAIDLILEKGTVGEVYNIGGHNEMHNIDIVKLICDYLDKPYSLIEHVTDRKGHDQRYAIDPTKIHDELGWLPETMFKDGIKKTIQWYLDNKEWWENIISGDYQNYYQEMYGKKQVLDEK
>NZ_CP022988.1|WP_003616128.1|271091_272264_+|methyltransferase-domain-containing-protein
MTDYYTSGEFAKRAHVSVRTIRYYDQQNLLKPSARSKGGARRYSDADFAKLQQILLLKYLGFSLGEIRGLTLGASDRRRLLDSLQIQRRLVEERIEEMTAIEATIDSTTQTLEAGKPVDWSRMLELLHRSTMTQSLKTQYQNATNISARIRLHRDYSMNKEGWFPWLFRQLDLTPGLKILEIGCGNGELWATSHDRLPEDCQVILTDISEGMLADAKKEIGEDSRFSYDQCDAAHLPFADEEFDLVVANHMLFYCDDIPQVLNEVRRVLKKGGRFCASTYSKRHMHEITDLVQEFNSQIILSSVNLYDRFGLDNGEEILAPFFAQVTCQRYDDAIELGEAEPVISYILSCHGNQNALLLDRYQEFKQFVEDEVAGGFHITKDAGTFICRK
>NZ_CP022988.1|WP_129335739.1|285605_285911_-|hypothetical-protein
MDTKEAIYVNKSLLELFGCELSSEFYDYYGQSLLNLISPGDQARVKEEFTDFVESAVDEERFRGDCQILTADARTLRVFCDMKYSVNQRYGALVYISFVLN
>NZ_CP022988.1|WP_003616108.1|285900_286230_-|hypothetical-protein
MFKQLRKASQNDYLLITATLILLVVFNLSLLSYVQGQQKAAERDQAKDYEEALKFADAALYEVKIAGKNNFASYKSSLTEKKHHNQLGLGLRALAAGDPTPLLGHADGY
>NZ_CP022988.1|WP_003616107.1|286769_287783_+|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MAKIGVLGAGTWGMALARMLSNSGHEVTVWSALPQEVDELSRTRRQKNLPGMVIPDEIKFTKEIAEACQDKDIILFAVPSVFVRSTAKTAAAFIPDGQIIVDVAKGIEPDTLLTLTEVIADELNKDGKHGNVHYVAMSGPTHAEEVAKDLPTTIVSACEDQAVAEKVQDVFMNKNMRVYTNSDRLGVELCGALKNVIALASGICSGLGYGDNMRAALIIRGMAEIKRLGLKMGGKEDSFDGLAGMGDLIVTATSKESRNNNAGYLIGKGKSAEEAKKEVGMVVEGINAIPAALELADKYDVEMPIVFAVDAVVNRGADARETVDALMLREKKSEMTK
>NZ_CP022988.1|WP_003616106.1|287919_288288_+|helix-turn-helix-transcriptional-regulator
MEKNMIGKYLRDLRRRRGMSQQELALALGVSKQTISNWEVGRKVPRMKAVEKIANIFGVSRNSILAGLPVEMLVQEGQEDRGVVDLTDRDIRLTYLGQQVPREYIDIIEKLMRCDIAERDAQ
>NZ_CP022988.1|WP_003616104.1|288393_288705_+|hypothetical-protein
MKEKNWLTWLTVLALVVGFVAMGASIWLSAQAAKQTQRNSQLAGQLYQASRTKSQEASSIKKRLDKLASDNSSLKKKNSRLAKETRHLSRPTRTCQQPARPRD
>NZ_CP022988.1|WP_095439214.1|289105_289774_+|IS607-family-transposase
MAEEYLGIKDAAKYLKVSISTLRRWEKKGLITPMRTAGNRRRYTVRQLDDMLGLNTQKELGAVARRGLVIGYCRVSSSGQKADLERQAEVVANYCEKQGYQFRIIKDIGSGMNYKKKGLQELLRLVCEGGCSKIVVNYKDRLVRFGYELIEMVCEEHNVDIEIINQTDDISYEEELTEDVLAIITVFSAKLYGKRSHRNEQIVAENRKLFSKDDKKETKDSN
>NZ_CP022988.1|WP_095439215.1|289742_291449_+|transposase
MTRRKLRTQIKTIRAYTVRLSDDELQELDKLFNNYGRCRDLLYGQLCGINHMTDVENWRGPRDRIRQHEGKIKQARKAVRSWKKAYAENKTQNMKVPDSGTVRLARQKLLNEQFHIQGRHVTEAVKEVCMNLNSMWTNLGLKLKKIVQANESLAKEERQYLNYVFTASYYWQLILQGRENEAESSKESKYPVLRAALTKDQLRHCFGYIRRLTRKHKPYPHSSAARCMLYDEIMWKVIQKDGADHLDIMTAVSGKRKQLKLTGPFCYANKKKRGDVQLILDRDKKRLEVHRAIKAAVHDLHKSKKKKVGMDKGLATLLSCSSGHEYGFNFSQLVNAEVERINRRNTNRNEYIQAAKELRHELSALQAKLAIKHSAKTERRLRNRIGSLERRISRLEERHLGSKLYHRQHARKQCNMERIMNMSIRKMLLTEKPDVLVKEDLSFTKEKLPKAANRYEAKVRRKLSSWSKGTLDGRIEYLCDCLGIRTVDVNPAYTSQFCPNCGARFSERKGTHHELTVCPNCGEMNANTAAAVNILRRADDKNITLYTPYKKVEKILEDRYANKQSVMA
>NZ_CP022988.1|WP_095439216.1|291698_291944_+|hypothetical-protein
MKKPKKILQLRLEDKNVFNAIHLNSIGYVFEFGNRGQIEKIGSQAHFKKLLRQISLNKLEESSLLVKKTENKKKQTSKKSE
>NZ_CP022988.1|WP_035182815.1|292260_293148_-|DNA/RNA-non-specific-endonuclease
MKKAMQKLTALLLASASFLVASPAKASSLADRNYQGQKVVTVNQDRPTFSKKALSTKKGAWQSYHKLDSLNRAGEADVLLNKRLMPAKAREPLYWNPTAWHNKKIAGGWLYNRSHLIGYQLTGQNNNPKNLITGTRQLNDPGMLKYENQVASYIKSSSRHYIRYRVKPIFRGRELLARGVEMEAQSTGSNAVRFHVYIFNVQDGVKLNYSNGTSVVTGAAKKSAKKTVVKKAAAKKSTSSKKKIKTSTTGRIVGNRRSKIYHVPGQAGYHMNSANAVYFRTETEAKRAGYRRALR
>NZ_CP022988.1|WP_035182812.1|293487_296742_+|SLAP-domain-containing-protein
MKKEEKKRGLFGKDYLMLSAMTIGLLAGAGKAQTVKADTVEKAKTEVKAATTATTTTANTTAAPTNTTTADTTTATNNNTAAGTNNTNTANNGTANTVTGNTNQATTGTTTGTPDPTNPGSTGTTTGTPDPTNPGSTGTNTGTKTDTKSTGNTTDNPGSASDNTQTHPGSFTGNTSSDETSELGKQNVSEDVSNENIGEGSVINSYLTTQAAKDNYAKLNDTGKKIVAAALREGSTLDLDKLTDTQIVALNKMVLNKTEDNQYTLKDYDSITKKIVERDSSSQIPLFKGEKIVNMPGLDKVKDAETGEEATMDIWDSWPVQDPETGYVQNWNGYQLAVAMMGIPHKSDSHLYLLYNKYGDNNFANWKVAGSIFGYNNDPKTGQWSGSAMLNADGSIQLFYANVLAQESNNQRVATITVNIGENADGVYIKSTENDHILFIGDGTVYQNYEQWKNSENRGANNPQMRDGHVFKDSDGTYYLAFETATGDLGDDPEGADNLYDWSRYGGNAAYNVSELFKLLNSTDMNTRAAVSNSAIGLLKLDMSDPKNPKVATDENGKQVLYKPLVKTVLSGDEIERPDLIKLNGKYYLFVDARVNHASDTDFAVQANIAVGDNVTMLGFVSDKVDGDYIPLNGDGLVLGASVPSTWRTATYSYYVVKINPANLKSDKITVNGVTYDKDYFVNHVVLINSYMGNRGEIAGKGLNSTLGPSFLVLVDGDKTTVLANSTTDQGVWDWNENSPKPELAAASLKEAKRSTDSYSFQVNKDGYWYLYNDSTDDGSIKMQTGFQYLAGQNKTVYYDPATGHMLYGFQKINGKTYYFAPGSGARFSGQIKLSGYWYLFSDKDGVMQTGFQYLAGQKKTVYYDPATGHMLYGLQKINGKTYYFAPGSGARVTGQIKINGKWYMFDKKTGVMQTGFQYIASQKKTVYYSPKTGQMLYGLQKINGKWYMFDKRSGAKISYQTVGTYIRLKHNAALYSAKGKKTKAKSYKKGLYTKSVGIRIIKGKVYYKLSNGKYIKAGNITVGKKRTLKKNAYIYVKKGKKVKALKGVQKKGSTKYTYGSVVIFQGKKFYAVASGKYIKSANF

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Crispr_ID: NZ_CP022988_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022988_2

598298-598392

Orphan

Consensus_repeat	Method
AGGCCAGCTCTAAGTCGGCGGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022988_2

>merge|NZ_CP022988|2|598298-598392|CRISPRCasFinder
AGGCCAGCTCTAAGTCGGCGGCTAAATCCGCGGCCAGTTCTGCCGTTAGTTCGACAAAATCCTCCTCAAGCCAGGCCAGCTCTAAGTCCGCGGCT

>NZ_CP022988|2|1|598298-598392|CRISPRCasFinder
AGGCCAGCTCTAAGTCGGCGGCT	AAATCCGCGGCCAGTTCTGCCGTTAGTTCGACAAAATCCTCCTCAAGCC
AGGCCAGCTCTAAGTCCGCGGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022988.1\|WP_035160948.1\|589485_590418_+\|homocysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|181899
NZ_CP022988.1\|WP_003616860.1\|602778_603024_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|153390
NZ_CP022988.1\|WP_157737568.1\|600326_600503_+\|ComC/BlpC-family-leader-containing-pheromone/bacteriocin	unknown	unknown	gnl\|CDD\|368018
NZ_CP022988.1\|WP_003616830.1\|590473_590935_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239825
NZ_CP022988.1\|WP_035160947.1\|586902_587868_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225420
NZ_CP022988.1\|WP_003616839.1\|595858_597292_-\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236426
NZ_CP022988.1\|WP_003616851.1\|599380_600151_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|223979
NZ_CP022988.1\|WP_003616841.1\|597360_597915_-\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238245
NZ_CP022988.1\|WP_148465396.1\|600526_601033_-\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|378820
NZ_CP022988.1\|WP_003616837.1\|595302_595779_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP022988.1\|WP_003616833.1\|591723_592746_+\|asparaginase	unknown	unknown	gnl\|CDD\|199207
NZ_CP022988.1\|WP_003616862.1\|603045_603330_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022988.1\|WP_002876645.1\|591295_591742_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP022988.1\|WP_003616849.1\|599017_599284_-\|DUF1294-domain-containing-protein	unknown	unknown	gnl\|CDD\|377743
NZ_CP022988.1\|WP_016395838.1\|592835_594203_-\|ISL3-like-element-ISLdl1-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP022988.1\|WP_003616859.1\|601945_602656_-\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
NZ_CP022988.1\|WP_003616856.1\|601148_601949_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|130314
NZ_CP022988.1\|WP_095439304.1\|603491_604538_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022988.1\|WP_095439201.1\|606271_607639_+\|ISL3-like-element-ISLdl1-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP022988.1\|WP_003616826.1\|588013_589408_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|236904

Protein	Function_ID	Function_description	E-value
NZ_CP022988.1\|WP_035160948.1\|589485_590418_+\|homocysteine-S-methyltransferase	gnl\|CDD\|181899	PRK09485, mmuM, homocysteine methyltransferase; Provisional.	9.19455e-158
NZ_CP022988.1\|WP_003616860.1\|602778_603024_+\|arginine-deiminase	gnl\|CDD\|153390	cd07321, Extradiol_Dioxygenase_3A_like, Subunit A of Class III extradiol dioxygenases. Extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into substrates using a variety of reaction mechanisms, resulting in the cleavage of aromatic rings. There are two major groups of dioxygenases according to the cleavage site of the aromatic ring. Intradiol enzymes cleave the aromatic ring between two hydroxyl groups, whereas extradiol enzymes cleave the aromatic ring between a hydroxylated carbon and an adjacent non-hydroxylated carbon. Extradiol dioxygenases can be divided into three classes. Class I and II enzymes are evolutionary related and show sequence similarity, with the two domain class II enzymes evolving from the class I enzyme through gene duplication. Class III enzymes are different in sequence and structure and usually have two subunits, designated A and B, which form a tetramer composed of two copies of each subunit. This model represents subunit A of class III extradiol dioxygenase enzymes. The A subunit is the smaller, non-catalytic subunit. Enzymes that belong to this family include Protocatechuate 4,5-dioxygenase (LigAB) A subunit, 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase (CarB) A subunit, Gallate Dioxygenase and proteins of unknown function.	1.56054e-22
NZ_CP022988.1\|WP_157737568.1\|600326_600503_+\|ComC/BlpC-family-leader-containing-pheromone/bacteriocin	gnl\|CDD\|368018	pfam04604, L_biotic_typeA, Type-A lantibiotic. Lantibiotics are antibiotic peptides distinguished by the presence of the rare thioether amino acids lanthionine and/or methyl-lanthionine. They are produced by Gram-positive bacteria as gene-encoded precursor peptides and undergo post-translational modification to generate the mature peptide. Based on their structural and functional features lantibiotics are currently divided into two major groups: the flexible amphiphilic type-A and the rather rigid and globular type-B. Type-A lantibiotics act primarily by pore formation in the bacterial membrane by a mechanism involving the interaction with specific docking molecules such as the membrane precursor lipid II.	0.00540816
NZ_CP022988.1\|WP_003616830.1\|590473_590935_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239825	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS). While ProX and ProRS-INS hydrolyze misacylated Ala-tRNA(Pro), the E. coli YbaK hydrolyzes misacylated Cys-tRNA(Pro). A few CD members are N-terminal, YbaK-ProX-like domains of an uncharacterized protein with a C-terminal, predicted Fe-S protein domain.	1.26469e-70
NZ_CP022988.1\|WP_035160947.1\|586902_587868_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	6.02922e-48
NZ_CP022988.1\|WP_003616839.1\|595858_597292_-\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NZ_CP022988.1\|WP_003616851.1\|599380_600151_-\|NUDIX-hydrolase	gnl\|CDD\|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	1.37468e-16
NZ_CP022988.1\|WP_003616841.1\|597360_597915_-\|cysteine-hydrolase	gnl\|CDD\|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	3.79494e-45
NZ_CP022988.1\|WP_148465396.1\|600526_601033_-\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	7.46166e-05
NZ_CP022988.1\|WP_003616837.1\|595302_595779_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	8.97479e-48
NZ_CP022988.1\|WP_003616833.1\|591723_592746_+\|asparaginase	gnl\|CDD\|199207	cd08963, L-asparaginase_I, Type I (cytosolic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type I L-asparaginases, which are highly specific for asparagine and localized in the cytosol. Type I L-asparaginase acts as a dimer. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase. One example of an enzyme with no L-glutaminase activity is the type I L-asparaginase from Wolinella succinogenes.	1.45064e-136
NZ_CP022988.1\|WP_002876645.1\|591295_591742_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.18145e-14
NZ_CP022988.1\|WP_003616849.1\|599017_599284_-\|DUF1294-domain-containing-protein	gnl\|CDD\|377743	pfam06961, DUF1294, Protein of unknown function (DUF1294). This family includes a number of hypothetical bacterial and archaeal proteins of unknown function.	3.05888e-19
NZ_CP022988.1\|WP_016395838.1\|592835_594203_-\|ISL3-like-element-ISLdl1-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.82258e-45
NZ_CP022988.1\|WP_003616859.1\|601945_602656_-\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	7.02641e-59
NZ_CP022988.1\|WP_003616856.1\|601148_601949_-\|ABC-transporter-permease	gnl\|CDD\|130314	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein. This model describes daunorubicin resistance ABC transporter, membrane associated protein in bacteria and archaea. The protein associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.00635e-06
NZ_CP022988.1\|WP_095439304.1\|603491_604538_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.26601e-17
NZ_CP022988.1\|WP_095439201.1\|606271_607639_+\|ISL3-like-element-ISLdl1-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	2.22218e-45
NZ_CP022988.1\|WP_003616826.1\|588013_589408_-\|amino-acid-permease	gnl\|CDD\|236904	PRK11387, PRK11387, S-methylmethionine permease.	0

>NZ_CP022988.1|WP_003616841.1|597360_597915_-|cysteine-hydrolase
MENEALLIIDYTNDFVDDKGALTCGAPAQALAGQIVSLADQFLAAGKWVILPTDKHFKGNPYHPETKLFPPHNLPNTWGREFYGPLQTWYNKHQDDKHVLVLDKSRYSAFCATGLDLFLRERKVSRVHLAGVCTDICVLHTAMDAYNHGYDITVHEKAVAALNDAGQEWALNHFKSCLGAEVVD
>NZ_CP022988.1|WP_003616839.1|595858_597292_-|nicotinate-phosphoribosyltransferase
MSLSHALITDLYEFSMANGYFETLPRDTEAVFDVFYRTVPDNGSFVVSAGLEQVVEQLRGFHYTKEDIDYLKSLNLFSGEFISYLETMTFDCVVYAIPEGTPVFPRVPILTVKGPLIQCQLLETFVLNLINHQSLIATKSRRINLAAAGRPVMEFGARRAQGPDASVLGARAAVIGGCGSTSNVLSAAKYNIPVAGTMAHAWVQSYPTELEAFEKWAEVYPDNALLLVDTYDVLTSGVPNAIKVFKELRAKGHKKFGIRIDSGDIAKLSRKARKMMDDAGFPEATITASNALNENVIHSLLQEGAPLDSFGVGEQLITSSSSPVLSGVFKLAALKIDDGEWQPKIKLSNSKEKVTLPGEKKAYRLYHKGTKNAFADVIALADESLPEEFVGINMDPMMTETEANLKDFDAELLTQVVVGPRAQSIETDTFKIQKHMYEKLAELPEETQRLLNPDRYPVYLTPALADLQAKMIKDHKL
>NZ_CP022988.1|WP_003616837.1|595302_595779_+|large-conductance-mechanosensitive-channel-protein-MscL
MPNRINLPDGQQAVESTKGFFGEFKTFISKGNVMDMAVGIIIGGAFTTIVKSLVSDIISPLLGLVGGMNFDQFSLKFAGVTLAYGKFLTAVINFLMMAFVLFLIVKAFNRGGFLIKKEEEVEEEATTKVCPYCKSEIDIEASRCPMCTSQLEEKMAEQ
>NZ_CP022988.1|WP_016395838.1|592835_594203_-|ISL3-like-element-ISLdl1-family-transposase
MNYTELSVATQDVMPNKGVLFFKSGLSDFIQVGEPIQNEDGLTFVGKLDECGDTFCPNCSRKLVKNGSLESTLKHVAIGGIHTNIRVSYARFRCLNIDCQFNTRSQSIPFKADGYRITKPLKEYTEKLLSYGLTLKAVAWLTGLDKMTVKSIHKSLLLSKFTTDGKTLIKPERQAKYLAIDEFKLHDGHKYATAIIDWETGYILYLAHGKKKAVVFEFMDHVGDEWMSKVEAVACDMNSDFEEAFKGRYPKLDIVYDRFHIIKNFNDKVVSEIRKDEQRRLAEEGSPEAAKLLKNSRYILMSKRSTLVQKDEDARKDKLVSTAGEIFNTPEIKAHGGNEVWYDELLEENKLFFTIDLVKDLLDQAYNSHDEVEMCVRLEEIIDICKATKNSHFIWFARLLYRHLRGIYTFAKYGISTGKLEGINNKIKTERRKGYGYPDDEYFFLRLMELSRKAS
>NZ_CP022988.1|WP_003616833.1|591723_592746_+|asparaginase
MRGKKMTNKKILLLSTGGTIASVASEEGLIPGKSGAELLHTLGGLPYEVEVKDILSLDSSNIQPEEWAFIAEQIYKLRRGFDGIVVSHGTDTMAYTASMLTFMLQGIDLPVVLTGSQAPMQAILSDAPDNLRVAFAAAATCKPGIYIAFNRQIMRGCRCVKIRTTGFDAFKSINVDPVAMVTSDGIDIKHKDFEYVPSEHAICTLNTKVETQVAMIKLFPGFDPAVLSAMVDSGVRGIVIEAYGLGGMNYMRRNMVKAIGEIIKRGVPVVACSQCLYERTDLTKYEVGRAAMLEGAISGRDMTSESAVTKLMWALGQGMGLEDVRAFFNKDIAGEVTITD
>NZ_CP022988.1|WP_002876645.1|591295_591742_+|MarR-family-transcriptional-regulator
MDLGLRVKKINDLMAKRGNYELKKLGLTFSQFHCLVYLEKCAGQQAPLKQLENHFEVAQATMAGIVGRLEGKGYVRSRLAESDKRVKIVCLTDEGRQICASAKKGMHKLQEKVEQLYSRQELSQLEKYLDRLYELLAEENREACEEKR
>NZ_CP022988.1|WP_003616830.1|590473_590935_+|YbaK/EbsC-family-protein
MAVERVKDFFKDTDVNVIELPESSATVALAAQALDTEPDQIAKTLSFLVDDAPILVVMAGEAKTDNHKYKATFHKKAKMIPFDQVEDYIGHAPGGVCPFAVKPGVKVYLDESLKRHTEVYPAAGSSNSAVRLTIPALENYSDYTAWVDVTKTA
>NZ_CP022988.1|WP_035160948.1|589485_590418_+|homocysteine-S-methyltransferase
MADLPTLLTQGPVTLDGSMSTPLEAWGEDTNSDLWTAKALADNPDLVYRVHQEYFKAGARVTITDSYQASLSAFMKHGLSEDAARGLIRESAAVAIKARDDFEKATGIHNFVAGSVGPYGAYLADGSEYRGDYALSHEEYVDFHAPRIEELVAGGVDCLAVETQPKLSEVRAILDHLKAKYPDLPVYVSFSLKDPATISEGLPLTEAVEEVSAYAQVFAAGANCFKLAWTVDVVKNLRASKLPIVVYPNSGAEYDPSVKKWVYPPEAADFGQAGADWLAAGAKLVGGCCTTMPEDIAGLAAAVKKVYTAF
>NZ_CP022988.1|WP_003616826.1|588013_589408_-|amino-acid-permease
MAQQEKVDHLERKMEARHIQMISLGGVIGTGLFLSSGYTISQAGPIGTIIAYFFGAILVYAVMLCLGELSVAMPYTGSFHVYAKNLLNPATGFTVAILYWLTWTIALGSEFTAAGIIMRHWFPSVPVWIWSLVFMILIFLSNFFSVKIFAESEFWFAAVKVAAIVAFIILGGLAVVGVIPLKGSQGAPGLTNLTEDGWFPTGFGGVFTTMLTVNFAFSGTELIGITAGEAKEPEKTLPKAIHTTLWRLIIFFIGSIFIMACLIPYKQAGVTESPFVHVFNMMGIPFASDLMNFVVLTAIISAGNSGLYASTRMLWSLGNEGTIPVVFAKTNKRGIPAISLLISMLGGVFSLLTSVYAADTIYLVLVSISGLAVVFVWMAIALCQLKFRQKWLKEGHTEDELKFKTPLYPFTPWFAFIASLASCLLIWFDPSQRVALYATIPFVIFCYVAHHFYAKNQEKKQTSL
>NZ_CP022988.1|WP_035160947.1|586902_587868_-|Crp/Fnr-family-transcriptional-regulator
MLTPNDSSSFENQLSPRQDLTFNSLQALFDQQGLPFSPPSSQFGILQFSNFDLLVSDQCPYTIKCAVFKGTDQDEFLDRQEFTGSLAAQFQQVYAFLEKHNPVESQIKGLYREDRPAYPKQALREALMNAIIHRDYSNPASSLINLYTDRVEFISFGGLMPGISLEDIQLGLSVCRNKRLADLFYQLKLVESYGTGLARIKSAYKGSRLAPQILAAPSSFKVVLPHYQAAVKAASKPVKKAVTPAPSPSPAPKPKARATGNEETVLAFGKEHGEFIRSDIEELLGVSPATATRLLRQMENSGLVLKRGKAKAIRYRISENS
>NZ_CP022988.1|WP_003616849.1|599017_599284_-|DUF1294-domain-containing-protein
MNNFWQSSLLLINLIAFALYGIDKAKARMHAWRIPERLLLTCGLLAPAGSGLGMLAFHHKIRKPYFCLTVLASFILWAAIGYFIFSLN
>NZ_CP022988.1|WP_003616851.1|599380_600151_-|NUDIX-hydrolase
MPELEKIVERPLITITNLIWSFNKETHRVQLLLVKRKDEPFADRWALPETLLRENESADQAAVRLIKEKIGLDLPETSTEQLATFTSSHRTPGERALALTYMTYLPAMPNLRPGYGASDVAWFAFENFGHKYELFSADKDLTFELEEKSHALAFDHDEIIAVAIQRIRNKLDYQPSILQILGPEFTLREAREVYAPFFQTTVDEIDNSNFRKTHGSLFTELGVQKNYHKSGRPPKIYCLKETQSNILWRKANNKQG
>NZ_CP022988.1|WP_157737568.1|600326_600503_+|ComC/BlpC-family-leader-containing-pheromone/bacteriocin
MDNNLHKVETLTDEELEQIVGGSIEGFLPYVSLYKGIRWGDHLKDFLPIIRKIDSVEI
>NZ_CP022988.1|WP_148465396.1|600526_601033_-|prolyl-oligopeptidase-family-serine-peptidase
MLYNEQRNLILVNYPIVYGNGGISDYQFLKEYFGKYKREHPNTEMILLGESYGGYLASLFAAEYIFRKIITISAFTSIDYQELFSSERSWLKNYLSENALDFYTLCRDNKVNTQTIFINGSRDSRVPYQQFLALPFMKKFKVNILPGFTHRECGTRLEYVISLVKQEL
>NZ_CP022988.1|WP_003616856.1|601148_601949_-|ABC-transporter-permease
MNPQHFRNISLGLRSIRIVANNEWRAFVHNKGLLLSMFMQPLITYGLLVMALNQNLASVHYKSLILPYKQYALTGVLSFFMTTQMSQAMYRATVDKEYGLLAIKFTNGVQPWHYLTGMSFFPIAGLLFQSAVLIVLGLATGGVYNLGLLLLSLLVLIISLEFWSTLGIVLSTRISSYQQRDIIMTLIFSPVAYAAPTLYVFSDNSPLIIKVLAYINPLSYQLKALRTVAFGIFNINDLLIALALTIIMIIFAQIILRRMPLSLAER
>NZ_CP022988.1|WP_003616859.1|601945_602656_-|metal-ABC-transporter-ATP-binding-protein
MISTNNLNIGYKDTVVVHDLSFSLDKGMFIALIGANGAGKSTLINSLIGVIPPVSGQISWKLKTDRVNPFNDVGFSPQSQLIDWYTSVYDNVYQGPLLAGFKPKEAQKTTKQALKLLDISDLSAKPVDHISGGQQQRVQIAREIAREPQVYILDEPTTGLDVETSEKLFTYLKQKVDAGSIVLTSSHDLTLLESYASHVLFLDDHEQKYFGPLTDFLDSGTSLREKYLNERKAIEK
>NZ_CP022988.1|WP_003616860.1|602778_603024_+|arginine-deiminase
MSIEFQKLIKKLQSDPITIGNFLADPEEFLKSTKLTNQEKKTLLARDVEALNDLGLTTSQVIGALSGAHSQQCSTNYPTRG
>NZ_CP022988.1|WP_003616862.1|603045_603330_+|hypothetical-protein
MPTARIEKCFNNFIESYTNESNIYIGSATYSLYSKFIIESYGLPVENRYSVSEIAQKLKQAGLDKVIVNYLIVRYLDGMYLLAQLQSKEETFWP
>NZ_CP022988.1|WP_095439304.1|603491_604538_+|protein-kinase
MARKFLTLNQKYHFDFKIISSIPYLEQMNMGYFGNSQVGKFITIYPDQSAVTETLELLYYYFHDDVEIRVGSDISYKQGLNVYYRYGTLLDDVENIDKRDKKLKPSSNVEKIYDYRLERYNSLPTRYLILKAIKQNGPSGVLLALDLQTKLKVIIRYADKYYNIESAGIDERDRLISASSLLEKDFVRNSSFFETVVDAFYVNDAFFVVTEYASGYNLDELAKNGQLGLYSLSERLEIFRNVLRGIYVLNDNLIIFRDLSFSNVILCPNHTIKIIDFGYAISLSGLSSFAGLTLNSAGTYGFFDPEMTIGKKQLDLYSLGKFLYYIVFPQSYLNYTSKIKVQYKFLCK
>NZ_CP022988.1|WP_095439201.1|606271_607639_+|ISL3-like-element-ISLdl1-family-transposase
MNYTELSVATQDVMPNKGVLFFKSGLSDFIQVGEPIQNEDGLTFVGKLDECGDTFCPNCSRKLVKNGSLESTLKHVAIGGIHTNIRVSYARFRCLNIDCQFNTRSQSIPFKADGYRITKPLKEYTEKLLSYGLTLKAVAWLTGLDKMTVKSIHKSLLLSKFTTDGKTLIKPERQAKYLAIDEFKLHDGHKYATAIIDWETGYILYLAHGKKKAVVFEFMDHVGDEWMSKVEAVACDMNSDFEEAFKVRYPKLDIVYDRFHIIKNFNDKVVSEIRKDEQRRLAEEGSPEAAKLLKNSRYILMSKRSTLVQKDEDARKDKLVSTAGEIFNTPEIKAHGGNEVWYDELLEENKLFFTIDLVKDLLDQAYNSHDEVEMCVRLEEIIDICKATKNSHFIWFARLLYRHLRGIYTFAKYGISTGKLEGINNKIKTERRKGYGYPDDEYFFLRLMELSRKAS

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Crispr_ID: NZ_CP022988_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022988_3

1150766-1151604

TypeI

Consensus_repeat	Method
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	PILER-CR
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CRT

12 spacers

cas2,cas1,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP022988_3

>merge|NZ_CP022988|3|1150766-1151604|PILER-CR,CRISPRCasFinder,CRT
GTCGCATCCCGCATGGGATGCGTGGATTGAAATCTTAAACTTGCCAGTTGCATCGACGGTCGCATTATGTCGCATCCCGCATGGGATGCGTGGATTGAAATTTAAAATCATTTAAACACGATCCAGTAGATGCAGTCGCATCCCGCATGGGATGCGTGGATTGAAATCGTCTAAAGGTTTGATGCAGACCATTGGGCCAAGTCGCATCCCGCATGGGATGCGTGGATTGAAATGCTTAACCTGGTCACTCTCCGTGATCTCTATCAGCGTCGCATCCCGCATGGGATGCGTGGATTGAAATCACAATCATAGAACTTGAAGCTTGAATCGCCTTGTCGCATCCCGCATGGGATGCGTGGATTGAAATTTTAAAGACATGGTTACCCAGGCGACCGAGTCTTGTCGCATCCCGCATGGGATGCGTGGATTGAAATTTTAAAAATCTTGTCAGAGTGGTTGAGCATGTCGTCGCATCCCGCATGGGATGCGTGGATTGAAATGGTCATGCTGAGGATGGTGTAGTAGCCGGTGGCAGTCGCATCCCGCATGGGATGCGTGGATTGAAATTGATTGTCCCGTTTGAGAAACCAGCAAGGATATACTTCGTCGCATCCCGCATGGGATGCGTGGATTGAAATTGTAGATTGTTGCGATGAGTCAGCAAGTGAGCGCTGTCGCATCCCGCATGGGATGCGTGGATTGAGAGGCTGAAGGGAAAGTAGCAGCAGAAAGAAGAAGCGTCGCATCCCGCATGGGATGCGTGGATTGAAATATTTGCTGGTACAAAAGTAACAGAGTTACAACAAGTCGCATCCCACATAAGATGTGTGGATCGAAAT

>NZ_CP022988|3|1|1150766-1151537|PILER-CR
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CTTAAACTTGCCAGTTGCATCGACGGTCGCATTAT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTAAAATCATTTAAACACGATCCAGTAGATGCA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CGTCTAAAGGTTTGATGCAGACCATTGGGCCAA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	GCTTAACCTGGTCACTCTCCGTGATCTCTATCAGC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CACAATCATAGAACTTGAAGCTTGAATCGCCTT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTTAAAGACATGGTTACCCAGGCGACCGAGTCTT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTTAAAAATCTTGTCAGAGTGGTTGAGCATGTC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	GGTCATGCTGAGGATGGTGTAGTAGCCGGTGGCA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TGATTGTCCCGTTTGAGAAACCAGCAAGGATATACTTC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TGTAGATTGTTGCGATGAGTCAGCAAGTGAGCGCT
GTCGCATCCCGCATGGGATGCGTGGATTGAGAG	GCTGAAGGGAAAGTAGCAGCAGAAAGAAGAAGCGTC
GCATCCCGCATGGGATGCGTGGATTGAAAT

>NZ_CP022988|3|2|1150766-1151604|CRISPRCasFinder
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CTTAAACTTGCCAGTTGCATCGACGGTCGCATTAT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTAAAATCATTTAAACACGATCCAGTAGATGCA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CGTCTAAAGGTTTGATGCAGACCATTGGGCCAA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	GCTTAACCTGGTCACTCTCCGTGATCTCTATCAGC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CACAATCATAGAACTTGAAGCTTGAATCGCCTT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTTAAAGACATGGTTACCCAGGCGACCGAGTCTT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTTAAAAATCTTGTCAGAGTGGTTGAGCATGTC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	GGTCATGCTGAGGATGGTGTAGTAGCCGGTGGCA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TGATTGTCCCGTTTGAGAAACCAGCAAGGATATACTTC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TGTAGATTGTTGCGATGAGTCAGCAAGTGAGCGCT
GTCGCATCCCGCATGGGATGCGTGGATTGAGAG	GCTGAAGGGAAAGTAGCAGCAGAAAGAAGAAGC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	ATTTGCTGGTACAAAAGTAACAGAGTTACAACAA
GTCGCATCCCACATAAGATGTGTGGATCGAAAT

>NZ_CP022988|3|2|1150766-1151604|CRT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CTTAAACTTGCCAGTTGCATCGACGGTCGCATTAT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTAAAATCATTTAAACACGATCCAGTAGATGCA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CGTCTAAAGGTTTGATGCAGACCATTGGGCCAA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	GCTTAACCTGGTCACTCTCCGTGATCTCTATCAGC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	CACAATCATAGAACTTGAAGCTTGAATCGCCTT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTTAAAGACATGGTTACCCAGGCGACCGAGTCTT
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TTTAAAAATCTTGTCAGAGTGGTTGAGCATGTC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	GGTCATGCTGAGGATGGTGTAGTAGCCGGTGGCA
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TGATTGTCCCGTTTGAGAAACCAGCAAGGATATACTTC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	TGTAGATTGTTGCGATGAGTCAGCAAGTGAGCGCT
GTCGCATCCCGCATGGGATGCGTGGATTGAGAG	GCTGAAGGGAAAGTAGCAGCAGAAAGAAGAAGC
GTCGCATCCCGCATGGGATGCGTGGATTGAAAT	ATTTGCTGGTACAAAAGTAACAGAGTTACAACAA
GTCGCATCCCACATAAGATGTGTGGATCGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022988.1\|WP_003613854.1\|1155649_1156813_+\|hydroxymethylglutaryl-CoA-synthase	unknown	unknown	gnl\|CDD\|213655
NZ_CP022988.1\|WP_095439242.1\|1151717_1153085_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP022988.1\|WP_003617719.1\|1158960_1159905_+\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|234786
NZ_CP022988.1\|WP_095439258.1\|1141224_1142484_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP022988.1\|WP_003617686.1\|1140553_1141222_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP022988.1\|WP_003617689.1\|1142531_1144964_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP022988.1\|WP_003617712.1\|1156976_1158335_+\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|377697
NZ_CP022988.1\|WP_003617694.1\|1145121_1145856_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187782
NZ_CP022988.1\|WP_003617729.1\|1163058_1164345_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|273080
NZ_CP022988.1\|WP_003617696.1\|1145852_1147727_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_CP022988.1\|WP_035165464.1\|1150306_1150597_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP022988.1\|WP_003617724.1\|1160045_1162307_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_CP022988.1\|WP_003617678.1\|1139115_1139757_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|237224
NZ_CP022988.1\|WP_003617700.1\|1149261_1150293_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP022988.1\|WP_003613864.1\|1162335_1162773_+\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_CP022988.1\|WP_003617679.1\|1139942_1140551_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|225232
NZ_CP022988.1\|WP_003617708.1\|1154419_1155646_+\|hydroxymethylglutaryl-CoA-reductase,-degradative	unknown	unknown	gnl\|CDD\|153082
NZ_CP022988.1\|WP_095439259.1\|1147746_1148601_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NZ_CP022988.1\|WP_003617706.1\|1153317_1154418_+\|thiolase-family-protein	unknown	unknown	gnl\|CDD\|238383
NZ_CP022988.1\|WP_035164818.1\|1158391_1158898_-\|aminoacyl-tRNA-deacylase	unknown	unknown	gnl\|CDD\|237976

Protein	Function_ID	Function_description	E-value
NZ_CP022988.1\|WP_003613854.1\|1155649_1156813_+\|hydroxymethylglutaryl-CoA-synthase	gnl\|CDD\|213655	TIGR01835, 3-hydroxy-3-methylglutaryl_CoA_synthase, 3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade. This clade of hydroxymethylglutaryl-CoA (HMG-CoA) synthases is found in a limited spectrum of mostly gram-positive bacteria which make isopentenyl pyrophosphate (IPP) via the mevalonate pathway. This pathway is found primarily in eukaryotes and archaea, but the bacterial homologs are distinct, having aparrently diverged after being laterally transferred from an early eukaryote. HMG-CoA synthase is the first step in the pathway and joins acetyl-CoA with acetoacetyl-CoA with the release of one molecule of CoA. The Borellia sequence may have resulted from a separate lateral transfer event.	6.15582e-131
NZ_CP022988.1\|WP_095439242.1\|1151717_1153085_-\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.22751e-44
NZ_CP022988.1\|WP_003617719.1\|1158960_1159905_+\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|234786	PRK00517, prmA, 50S ribosomal protein L11 methyltransferase.	1.40128e-92
NZ_CP022988.1\|WP_095439258.1\|1141224_1142484_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.62691e-28
NZ_CP022988.1\|WP_003617686.1\|1140553_1141222_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.40873e-66
NZ_CP022988.1\|WP_003617689.1\|1142531_1144964_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	7.02358e-50
NZ_CP022988.1\|WP_003617712.1\|1156976_1158335_+\|threonine/serine-exporter-family-protein	gnl\|CDD\|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	3.07413e-64
NZ_CP022988.1\|WP_003617694.1\|1145121_1145856_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.92243e-87
NZ_CP022988.1\|WP_003617729.1\|1163058_1164345_+\|histidine--tRNA-ligase	gnl\|CDD\|273080	TIGR00442, hisS, histidyl-tRNA synthetase. This model finds a histidyl-tRNA synthetase in every completed genome. Apparent second copies from Bacillus subtilis, Synechocystis sp., and Aquifex aeolicus are slightly shorter, more closely related to each other than to other hisS proteins, and actually serve as regulatory subunits for an enzyme of histidine biosynthesis. They were excluded from the seed alignment and score much lower than do single copy histidyl-tRNA synthetases of other genomes not included in the seed alignment. These putative second copies of HisS score below the trusted cutoff. The regulatory protein kinase GCN2 of Saccharomyces cerevisiae (YDR283c), and related proteins from other species designated eIF-2 alpha kinase, have a domain closely related to histidyl-tRNA synthetase that may serve to detect and respond to uncharged tRNA(his), an indicator of amino acid starvation; these regulatory proteins are not orthologous and so score below the noise cutoff. [Protein synthesis, tRNA aminoacylation].	0
NZ_CP022988.1\|WP_003617696.1\|1145852_1147727_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.94376e-93
NZ_CP022988.1\|WP_035165464.1\|1150306_1150597_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.54047e-25
NZ_CP022988.1\|WP_003617724.1\|1160045_1162307_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_CP022988.1\|WP_003617678.1\|1139115_1139757_+\|FAD-binding-protein	gnl\|CDD\|237224	PRK12842, PRK12842, putative succinate dehydrogenase; Reviewed.	3.55336e-22
NZ_CP022988.1\|WP_003617700.1\|1149261_1150293_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	4.85739e-170
NZ_CP022988.1\|WP_003613864.1\|1162335_1162773_+\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	5.77324e-87
NZ_CP022988.1\|WP_003617679.1\|1139942_1140551_+\|GTP-pyrophosphokinase	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	1.08103e-64
NZ_CP022988.1\|WP_003617708.1\|1154419_1155646_+\|hydroxymethylglutaryl-CoA-reductase,-degradative	gnl\|CDD\|153082	cd00644, HMG-CoA_reductase_classII, Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR). Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR), class II, prokaryotic enzyme is a homodimer. Class II enzymes are found primarily in prokaryotes and Archaeoglobus fulgidus and are soluble as they lack the membrane region. Enzymes catalyze the synthesis of coenzyme A and mevalonate in isoprenoid synthesis. Bacteria, such as Pseudomonas mevalonii, which rely solely on mevalonate for their carbon source, catalyze the reverse reaction, using an NAD-dependent HMGR to deacetylate mevalonate into 3-hydroxy-3-methylglutaryl-CoA. Human and bacterial HMGR differ in their active site architecture.	0
NZ_CP022988.1\|WP_095439259.1\|1147746_1148601_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	2.67496e-106
NZ_CP022988.1\|WP_003617706.1\|1153317_1154418_+\|thiolase-family-protein	gnl\|CDD\|238383	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.	3.2487e-161
NZ_CP022988.1\|WP_035164818.1\|1158391_1158898_-\|aminoacyl-tRNA-deacylase	gnl\|CDD\|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	2.28201e-65

>NZ_CP022988.1|WP_035165464.1|1150306_1150597_+|CRISPR-associated-endonuclease-Cas2
MMVIVSYDVNTETASGKKRLRNVSKICNDYGQRVQNSVFECLVDSTKLEEMKERLLKVYDEECDSLYFFNVGKKYENKVQSYGCKQVLDLGKPVVF
>NZ_CP022988.1|WP_003617700.1|1149261_1150293_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MRQLLNTLYVNTPEAYLAADGNNVKVLIDQKCVGEVPLQNFESIVTFGYSGVSPGLMQKCLDQGISISFISKSGYLKGRVVGKPTGNVYLRRIQYRLADTQAASLEISKNFIIGKVYNQRWIVERYIRDHSFQIDADMFKKVSESLKNGIEEIRNAENMDVLRGVEGKLATDYFSIFDQMIINQKEDFFYHGRNRRPPLDRVNALLSLTYTLLGNECASGLIANGLDPYVGFMHVDRPGRESLALDLTEELRGVMADRFVLKLINKKMLHADDFVEKESGAILLKDGARKRVLAEWQNNKVTTIEHPFLKEKIEWGLIPFVQAQLLARYLRGDLDGYPPFLWK
>NZ_CP022988.1|WP_095439259.1|1147746_1148601_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MANVLNHRIDFKVVFSVAGANPNGDPLNGNRPRQTSDGYGEVSDVAIKRKLRNRLQEMGEKIFVQSQDRADDGLKSLKARADSVKELKGQKDESKYQEVACQTWFDVRAFGQVFAFDKGSSVGVRGPVSIQTARSITPIMINDMQITKSVNSKDAAGRSSDTMGMKYSIDYAVYQFNSSINVQLAEKTGFTEEDANAIHEALKTLFYNDESSARPAGSMEVLRVYWWEHKNKLGDESPAKIFRTVEIKPNEGVDVVKSTEDIDWGSADSAAKTIQCDKLDIFED
>NZ_CP022988.1|WP_003617696.1|1145852_1147727_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLSEFVDVYDKNEKNLGITSYRIYHPKSGEESKKAYQMLPVSHIFLNCTLQIDLNADGTFAGAFVVDDPKTIVPATIESSIRSGSGSYLVPLPVDDKLQYLARDYSKWSGDEKYIESHKKYLEQFRAYLSFLKEYPDQYVYRTLQAVYRYVTENDIINDLWTGKIFGENVAKEKVAGNNLFKSTVRFNIRNPENVKRFENRRFFDAWTQYYHQVLQTDTVSGGTDEGIDYITGEENVILTSKHPKGILDNAANAKLISANDTTNFTFKGRFLTADEAVTIGYDSSQKAHAAMKWLLTKQGFKIGDRYYLAWEVNGENTADLSIVSQNPLLALAQKKFAETTEIDTNTNIAENFRKILIDGANKDDYSLQGSVHLIELESPVNGRFGVVYYQAMSLQQYINKFASWYGKITIDDRQSFFNLKQVCYDIYGDRVDDKRMAATVSQLSHMILGSQIVPWSLLSAIYNRAIRPASFNDDKGWRRVMRTASKLFKAYYDEGEIKTMLNDSYHDRSYSFGRLLAIADVIEEGVLQGSENSEGRVTNAKRYMSSFAQRPLDTWKIIYTNLQPYLRKSKYSFKASKLIDEIFASLDAEDKHLNDPLNGKFLIGYSQQRNDWYQKKKTSNE
>NZ_CP022988.1|WP_003617694.1|1145121_1145856_+|type-I-C-CRISPR-associated-protein-Cas5
MEENTTFNFKVYGDYALFTDPIIKIGGEKFTYPVPTYQALKGITESIYWKPTIQIYIDKVRVMNPIITEAKDIRVPKYNDMTKTDLSRYTYLKDVEYQVQAHFEFNQNRPDLAGDRNAKKHYAIMKRCIEKGGRRDIFLGTRECQGYVEPCKFGEGESFYDNSDDRLFGTMVHGIDYPDETGRDELGVRLWNVVMKQGVIEFPRPDDETLVRRSLHKLKAKQFSLSNIESVDALYVELLKEGDL
>NZ_CP022988.1|WP_003617689.1|1142531_1144964_+|CRISPR-associated-helicase/endonuclease-Cas3
MTYIAHTKENSEEIQTLRDHLWNSKMYAEKYGDILGIPHVTGVAALVHDLGKYRQEFQKYIRHSEKAKKGSVDHSSFGAVFLKEKVKELSQQPEGFSADSLFAEIISNAVFSHHNSLGLKDYLNARLKSPYYERVEKFDIDPEKKIELKQAESLFYQETMAENDFNIYLKTAMREFSQLFKELLKDQDGLLDNLYYVGQFIYSCLLDADRTDTSLFSFGKSATEYQYDEIFEQYYGKLLNSISKFDQSTKINQARSEMSDECDAFADQADGIYRLSIPTGGGKTLASLRYGLKHAIKTKKKHIIYVLPYITIIEQNVEVIRNMLNGNSKNTTNILEFHSNVSNDLTEDDTEVEKTVRLAEDNWDSPIVITTTVQFLNCIYAKSTVNRRRFHNLCDSVIIFDEVQKLPLKNISMFNKLLNFLSNIGKCDIVLCTATQPAFDNLSSGTLLKLAGKPEMISNLSSRIQQFKRVKIIDRTKKDGADHQLTVTEAAEMILEAARAQGSVLAIFNTISATERVFNEIKKGAQDYVYILTTRMCPEHRKKAIEKIKELLAEGKNVICISTALIEAGVDISFSCVFRSLCGLDSIVQSAGRCNRNAEKKYGTVNLILMDQTAEKLNSLQEIKNGKEIVQGMLDGKYKADSFLEDETINYYFQVLYRDADKEYLVSDHGYQVYLADCIDGSKLMQKYVNEYHSGPKTIEGSASETIARNFEVIDEDTVSLIAPYGLGKEIITKLNSREGSRQLKELLKVSQPYLVGVYRTKLKELIDKGAVISLGDEYQKNEIFAIRDDHYDDGIGLVENPTNNNFVSF
>NZ_CP022988.1|WP_095439258.1|1141224_1142484_+|HAMP-domain-containing-histidine-kinase
MIKKIRRRFIWLATLSLFLVMFFSFSSLIGISLFESNHEADQVLSIIVKNNGRLDEVQAKKRLGDQYNKEGIFKYRYFTAKINTKKQTLTVIDADHIIGYSINSVSSRKKQISMRLSAGQLKGTIQSNGVRFRYLAKKISANKYYICFIDLSPLMQSALLLVRYALIFTFSGILVFVIIMALLADKAIQPIKDAYDKQRRFITNAGHELKTPLAVISANAEMEEPLGNDDEWNESTKEQVVRMTGLINQLITLTRMSEPEELVLSKVNFSEITKESADSFKSVLAKDNKKYVVSIDPDLYINAEQHSLLELANILIDNAQKYCDPEGEVMVVLAKSRLNQNAVLTVTNSYKNGAGIDTNRFFERFYREDESHHYDQKQKNGFGIGLSMAQDLVAAFGGKINAGWSDGVMNFTVTFKRVH
>NZ_CP022988.1|WP_003617686.1|1140553_1141222_+|response-regulator-transcription-factor
MKILLAEDEAQLNRVLTVAMQKSGYDVDSVFNGQEAVDAVKKHPYDVIIMDIMMPVKNGLDAVKEIRATGDKTYIMMLTAKSEIDDRVTGLDVGADDYLTKPFSLKELLARLRSKERRSEDYNSTQELNYDNLKLDLNSQELSSNNSISLSKQETGLMRYFLLNPGKAISTEELFNHVWKNEDESEDVVWVYVSFLRSKLASIGANVQISGEKGGEFCLERA
>NZ_CP022988.1|WP_003617679.1|1139942_1140551_+|GTP-pyrophosphokinase
MSIYGKYADYLPQILDSVLQQIQGIGQEYSAKHGQKLYEYLKGRVKGEESMTQKCERKGMPLTPESALIENRDAIGLRIVCNFIDDIYTCIDLLKKQDNFKIINEKDYITDAKPNGYRSYHLIMEVVTPFEDVHGNKPGTYYVEIQLRTIAMDTWASLEHEMNYKHDIKNPERISKELKRVADELASCDVSMQTIRQLIKEG
>NZ_CP022988.1|WP_003617678.1|1139115_1139757_+|FAD-binding-protein
MNEGLLCDYPMSYGEEPTLRHSPYYAIVDQEYVDKMRDEGLYEYLTKRGANHDNWFIGSYYKQRGALKSLDSDLEEGIHEGWIVKADTLEELAKKTGFDHLTGTVASYNSYCEKGEDEQFGANPWYLSSVKQGPFYAIECEVSAWSTFGGVKTDDECRALAEDDQVIPGMYVVGTDNGSMMYSPYYDIPGFCYGSCIGSGVIAGQGASAYVKA
>NZ_CP022988.1|WP_095439242.1|1151717_1153085_-|ISL3-family-transposase
MNYTELSVATQDVMPNKGVLFFKSGLSDFIQVGEPIQNEDGLTFVGKLDECGDTFCPNCSRKLVKNGSLESTLKHVAIGGIHTNIRVSYARFRCLNIDCQFNTRSQSIPFKADGYRITKPLKEYTEKLLSYGLTLKAVAWLTGLDKMTVKSIHKSLLLSKFTTDGKTLIKPERQAKYLAIDEFKLHDGHKYATAIIDWETGYILYLAHGKKKTVAFEFMDHVGDEWMSKVEAVACDMNSDFEEAFKGRYPKLDIVYDRFHIIKNFNDKVVSEIRKDEQRRLSEEGSPEAAKLLKNSRYILMSKRSTLVQKDEDARKGKLVYTAGEIFNTPEIKAHGGNEVWYDELLEENKLFFTIDLVKDLLDQAYNSHDEVEMCVRLEEIIDICKATKNSHFIWFARLLYRHLRGIYTFAKYGISTGKLEGINNKIKTERRKGYGYPDDEYFFLRLMELSRKAS
>NZ_CP022988.1|WP_003617706.1|1153317_1154418_+|thiolase-family-protein
MQDIYIVAAKRTPFGRYHKQLADFSAIDLGQIALHGALKEAGLDAEALDALFMGNVLSAGLGQNIARQIALNAGMRQDSVAVSINEVCGSSLKAARLAEAQMLIGDLGLVAVGGSESMTNAPKEIMFSDGLVDSFSGKSMGITAENVAKRNHISRQDADAFSLSSHQKAVKAQAEGLFADEIIQIEDLKQDENVRPDTSLEALAGLKTSFLEDGTVTAGNASPISDGASMIILATAEKVAEYQLTPLAKLGAYAEVGYDPEFMGYGPYYAIRKLLNETGRQVADYDFFEINEAFAATTLAVVRDLEIPLAKVNKQGGAIALGHPLGASGTRLLATAARQLQRGGQRAIASLCIGGGLAIAFEIEKA
>NZ_CP022988.1|WP_003617708.1|1154419_1155646_+|hydroxymethylglutaryl-CoA-reductase,-degradative
MKFYQLPPEERRQFLQEDGVALEDIPAADLARLDEMSENVVGEVKFPLSCLTSALVNGKNWRIPMTTEEASVVAAANHGMSVFAKAGGVKATSQRDGIYGQIVLEVTEAFSLAGFKKEFPAYIKEANKEFASLIRHGGGLKDLTARQEADLVYLLALVDPAEAMGANKTNAILEFLAQKMLAFPGVEAKLFAILSNYPSQLTTAKVAIPVSLLSKKGDLAEGREVAKKMALLAKIGSSDPYRAVTNNKGIMNGVDAVMLATGNDYRAVEAACHAYAAKSGQYRSLSSWKLEGEKLLGQVTLPLALGVVGGSISSRPDIRQSYAILGKIKAAELAELTASVALANNFAALNAISTKGIQAGHMRLQSRNVVQTLPAAAEEKEAVYQMMISQGKYGETAAKNFLKELRGQ
>NZ_CP022988.1|WP_003613854.1|1155649_1156813_+|hydroxymethylglutaryl-CoA-synthase
MDIGIDQIGFYTPNKFVDMVDLANARNQDPNKFLIGIGQDRMAVADKTQDAVSMGINATAEYLDQVDLEQLGLLIFATESGIDQSKSASLFVKEALNLPARIRTFEIKEACFALTASLQVARDYVRAHPHHSAMIIGSDIARYGLATAGEVTQGAGAISMLIKENPAIIALEDGHTSHSENINDFWRPNNLATAVVDGHYSRDVYLDFFKSTFKPFLAEKQLQVSDFAGICYHLPYTKMGYKAHKIAIEGQDDETVKRLSDNFQLSAKYSRQVGNIYTASLYMSVLSLLENGDLEAGDRIGFFSYGSGAMAEFFSGKVVAGYQKRLRPALHARMLKERIRLGVGQYEDIFTEGLENLPENVEFTSDANHGTWYLAGQEGYVRQYKQK
>NZ_CP022988.1|WP_003617712.1|1156976_1158335_+|threonine/serine-exporter-family-protein
MKTESTEQEYHHHLSHHHHMRVQWEEFFQSDDETKIKEATLIEKGSIISRVGMMMLSCGTGAWRVRDAMDTLARTLDLTCSTDIGLISIVCTYFDVDNQSYSQSLALPTTGVNMAKLNELEKFVRQFEAAGGDFEIKTIRRRLGEIEHMKGRYPLWGSSLAAALACGGFIFLLGGGIPEIICSFIGAGLGQFARGSLAKRRITIAATTAVGVAAACLSYYLAFMLGHLFFNVDMIHMRGYIGAMLFVIPGFPFITSGLDIAKLDMRSGLERMAYAIFIILIATGTGWVMATALQIKPGDLPALHLSKAILTACRLVASFCGVFGFSLMFNSHRRMAAAAGLVGAIANTMRLSLVDFAHFPAPLAAFLAALLAGLLAGYVREKVGYPRIALTVPSIVIMVPGLYMYRGIFLLVLTNVGAGATWMTEALMLVMSLPAGLLTARILTDKKWRRVD
>NZ_CP022988.1|WP_035164818.1|1158391_1158898_-|aminoacyl-tRNA-deacylase
MSKKKKNKDKLDKTLVEKILDQHKIAYEQHISKISEDHGVAQVGTGKPVLDGHPVYKTLAVNGNKTGPIVGVVPLSGHLDLKKIAKASGNKKCEMIPLKQLEKTTGYVHGANTPIGIYHSKKFPIFLDESVLNEDGIWVSSGEVGRSVMVNPLDLQKLVKATVADLQE
>NZ_CP022988.1|WP_003617719.1|1158960_1159905_+|50S-ribosomal-protein-L11-methyltransferase
MKLLEIKIESSYDVEDALAYFATEDLKALGTEARRRSDFEQAGWLHDSTVVDMDDIPNLPDELEFIAYFDEETDPEETVKCFKDKLAELAGYGLKTAPGEISVDYVADQDWNTVWQKYYHVINLSRHLAIVPEWEDYQPAFKDQEIIRLDPGLAFGTGNHQTTQLAMLGIERAMVKPLTVADVGTGSGILAIAAHKLGAKSVLATDISDESMTAAKENAALNGIQDIALQKTSLLAGVDGKFDLIVANILAEILLDLIPQLDSHLSEDGQVIFSGIDYLQLPKIEQALAENGFQIDLKMRAGRWIGLAISRKHD
>NZ_CP022988.1|WP_003617724.1|1160045_1162307_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MSKYVEMTHEQVMAACKKYMTADQLAFVESAYQFAARAHEGQTRASGQPYIVHPTQVAGTLANLGLDPDTVAAGFLHDTVEDTSVTNDDIKEEFGADVAFIVDGVTKLNKYEYKSHKEFLAENHRKMLIAMAKDLRVILVKLADRLHNMHTLEHLRPDKQRRIAAETLDIYAPLADRLGIGTIKWELEDMSFHYMNPEAYYKIVSMMDAKRSEREDYIKDAIDYLRGTLDSLGIKYDISGRPKHIYSIYKKMVNKHKDFNEIYDLLAVRVIVPTVKDCYAVLGAVHTKWKPMPGRFKDYIAMPKANGYQSLHTTIIGPGGKPLEIQIRTEEMHKVAEYGVAAHWAYKRGNFQGVDEKDGGALDIGREILELQKDSNNADEFMEAVHSDIFADKVYVFTPKGEVYELPKGSVTLDFAYAIHTQVGDHGIGAKVNDKLVPLDYKLKNGDVVDILTQSNARPSRDWAEMVKTSRAKNKIRRYFRDVDREESLARGKSELVDLLKENGLSAKDFLDKSHIDEVLDHFSFKTDEDMYAAIGFGNMSAVSIYNRLTADLRRQQEEEKQKQFEAQIMSAGQQAAASSVVKKPASQKDDAKSKTKGKKPDSLVRVQGLEDLDMHFAKCCNPVPGDPIVGYVTKGRGVTVHRADCRNVVSADPAAQGRMIDVEWNNIDEGKQASFNANFELFGYNRQKLLGDVINRLNALTKNITNVSASVNEENIAHFYITVEVRNAAQLNDIMAKLRDIPDVYGTKRTDN
>NZ_CP022988.1|WP_003613864.1|1162335_1162773_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRVVIQRVNHAAVRIDGETVGQIQKGLLLLVGLAEGDGEEQVVKAADKIAKMRIFEDEAGKTNLGIKDVGGQILSVSQFTLLADTKKGNRPSFVHAMRPPKSSQLWEEFNQELVKRGLTVETGEFGADMKVELENDGPFTIVLDL
>NZ_CP022988.1|WP_003617729.1|1163058_1164345_+|histidine--tRNA-ligase
MRVQRPKGTVDILPETSGQWEKVEQTARDLFKRANYHEIRTPSFENYELFSRSSGETSDVVEKEMYDFEDKGGRHIALRPEGTAGVVRAYVENKIYGPDYVKPFNVYYIAAMYRYERPQAGRQREFHQIGVESFGSDGYLADVETILLGHDLLAELGVKNYELHINTLGDSEVRQAYHDALVDYFTPVKDQLSEDSQRRLGKNPLRILDSKAEEDQQFLPEAPKIRDYLDEESKENFNKILASLDKLGVKYVIDDDLVRGLDYYTGVIFEFMVDDPTLWASPSTVLGGGRYNHLVEEFSGPETPAVGFGIGEERLMLVLSKQNPEMFEDQGIDFFITNIGEGTDIKAVEVARQLRSLGFSAQYDVDQKKLKAQFRKADRVGARYVVTLGAKELAEGKLTVKRLSDGQQFSLEFTDLEDKANLLSKIEK

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Crispr_ID: NZ_CP022988_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022988_4

1535202-1535305

Orphan

Consensus_repeat	Method
CCGCTGCCCCCGCACTTGTCACAGGT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP022988_4

>merge|NZ_CP022988|4|1535202-1535305|CRISPRCasFinder
CCGCTGCCCCCGCACTTGTCACAGGTCGTCTGCCGCTGGATTATGCCCAAAACGCTTCTTTGCGTAATGGTCATCATGCCGCTGCCCCCGCACTTGTCGCAGGT

>NZ_CP022988|4|3|1535202-1535305|CRISPRCasFinder
CCGCTGCCCCCGCACTTGTCACAGGT	CGTCTGCCGCTGGATTATGCCCAAAACGCTTCTTTGCGTAATGGTCATCATG
CCGCTGCCCCCGCACTTGTCGCAGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022988.1\|WP_003615420.1\|1548224_1548782_+\|serine-acetyltransferase	unknown	unknown	gnl\|CDD\|200082
NZ_CP022988.1\|WP_003615403.1\|1532703_1534542_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP022988.1\|WP_003615408.1\|1537789_1538389_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237631
NZ_CP022988.1\|WP_003615419.1\|1547074_1548259_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|181076
NZ_CP022988.1\|WP_035161317.1\|1529231_1529759_-\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NZ_CP022988.1\|WP_080553976.1\|1540663_1541257_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP022988.1\|WP_003615387.1\|1521805_1522660_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP022988.1\|WP_035182731.1\|1525373_1526507_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP022988.1\|WP_003615398.1\|1528849_1529152_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP022988.1\|WP_035182733.1\|1538423_1539473_-\|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NZ_CP022988.1\|WP_095439278.1\|1544049_1544844_+\|transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP022988.1\|WP_003615395.1\|1526623_1527649_-\|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|237363
NZ_CP022988.1\|WP_003615411.1\|1539608_1540550_-\|riboflavin-biosynthesis-protein-RibF	unknown	unknown	gnl\|CDD\|235536
NZ_CP022988.1\|WP_003615389.1\|1522837_1525096_+\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319771
NZ_CP022988.1\|WP_003615418.1\|1546141_1547053_+\|cysteine-synthase-family-protein	unknown	unknown	gnl\|CDD\|223110
NZ_CP022988.1\|WP_052109142.1\|1542764_1543181_-\|Arm-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379665
NZ_CP022988.1\|WP_003615400.1\|1529748_1532025_-\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_CP022988.1\|WP_003615401.1\|1532021_1532723_-\|class-A-sortase	unknown	unknown	gnl\|CDD\|320680
NZ_CP022988.1\|WP_003615406.1\|1535885_1537730_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_CP022988.1\|WP_003615397.1\|1527850_1528738_-\|cation-transporter	unknown	unknown	gnl\|CDD\|224151

Protein	Function_ID	Function_description	E-value
NZ_CP022988.1\|WP_003615420.1\|1548224_1548782_+\|serine-acetyltransferase	gnl\|CDD\|200082	TIGR01172, Serine_acetyltransferase, serine O-acetyltransferase. Cysteine biosynthesis [Amino acid biosynthesis, Serine family].	6.49743e-64
NZ_CP022988.1\|WP_003615403.1\|1532703_1534542_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP022988.1\|WP_003615408.1\|1537789_1538389_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237631	PRK14162, PRK14162, heat shock protein GrpE; Provisional.	1.4363e-88
NZ_CP022988.1\|WP_003615419.1\|1547074_1548259_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|181076	PRK07671, PRK07671, bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase.	0
NZ_CP022988.1\|WP_035161317.1\|1529231_1529759_-\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	1.60932e-94
NZ_CP022988.1\|WP_080553976.1\|1540663_1541257_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.58469e-47
NZ_CP022988.1\|WP_003615387.1\|1521805_1522660_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	6.40204e-51
NZ_CP022988.1\|WP_035182731.1\|1525373_1526507_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	4.7779e-44
NZ_CP022988.1\|WP_003615398.1\|1528849_1529152_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	8.52927e-14
NZ_CP022988.1\|WP_035182733.1\|1538423_1539473_-\|heat-inducible-transcriptional-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	1.13244e-124
NZ_CP022988.1\|WP_095439278.1\|1544049_1544844_+\|transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.05306e-07
NZ_CP022988.1\|WP_003615395.1\|1526623_1527649_-\|branched-chain-amino-acid-aminotransferase	gnl\|CDD\|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	0
NZ_CP022988.1\|WP_003615411.1\|1539608_1540550_-\|riboflavin-biosynthesis-protein-RibF	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	8.5273e-112
NZ_CP022988.1\|WP_003615389.1\|1522837_1525096_+\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319771	cd02076, P-type_ATPase_H, plant and fungal plasma membrane H(+)-ATPases, and related bacterial and archaeal putative H(+)-ATPases. This subfamily includes eukaryotic plasma membrane H(+)-ATPase which transports H(+) from the cytosol to the extracellular space, thus energizing the plasma membrane for the uptake of ions and nutrients, and is expressed in plants and fungi. This H(+)-ATPase consists of four domains: a transmembrane domain and three cytosolic domains: nucleotide-binding domain, phosphorylation domain and actuator domain, and belongs to the P-type ATPase type III subfamily. This subfamily also includes the putative P-type H(+)-ATPase, MJ1226p of the anaerobic hyperthermophilic archaea Methanococcus jannaschii. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP022988.1\|WP_003615418.1\|1546141_1547053_+\|cysteine-synthase-family-protein	gnl\|CDD\|223110	COG0031, CysK, Cysteine synthase [Amino acid transport and metabolism].	6.44657e-143
NZ_CP022988.1\|WP_052109142.1\|1542764_1543181_-\|Arm-DNA-binding-domain-containing-protein	gnl\|CDD\|379665	pfam14659, Phage_int_SAM_3, Phage integrase, N-terminal SAM-like domain. This domain is found in a variety of phage integrase proteins.	4.3883e-10
NZ_CP022988.1\|WP_003615400.1\|1529748_1532025_-\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	5.61219e-160
NZ_CP022988.1\|WP_003615401.1\|1532021_1532723_-\|class-A-sortase	gnl\|CDD\|320680	cd06165, Sortase_A, Sortase domain found in class A sortases. Class A sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Firmicutes). They perform a housekeeping role in the cell as members of this group are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is cleaved at a conserved cell wall-sorting signal (Class A sortases recognize a canonical LPXTG motif, X can be any amino acid), and covalently linked to peptidoglycan for display on the bacterial surface. The prototypical sortase A protein from Staphylococcus aureus (named Sa-SrtA) cleaves the amide bond between threonine and glycine residues of the canonical LPXTG motif in a wide range of protein substrates with diverse functions that can promote bacterial adhesion, nutrient acquisition, host cell invasion, and immune evasion. Next, it catalyzes a transpeptidation reaction by which the proteins are covalently linked to the peptidoglycan precursor lipid II. SrtA is therefore affects the ability of a pathogen to establish successful infection. SrtA contains an N-terminal hydrophobic segment, a linker region and an extra-cellular C-terminal catalytic domain. The hydrophobic segment functions as both a signal peptide for secretion and a stop-transfer signal for membrane anchoring. The catalytic domain contains the catalytic TLXTC signature sequence where X is usually a valine, isoleucine or a threonine. The gene encoding SrtA is generally not located in the same gene cluster as its substrates while the gene encoding SrtB is usually clustered in the same locus as its substrate.	1.8512e-58
NZ_CP022988.1\|WP_003615406.1\|1535885_1537730_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP022988.1\|WP_003615397.1\|1527850_1528738_-\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	9.9708e-85

>NZ_CP022988.1|WP_003615403.1|1532703_1534542_-|elongation-factor-4
MDLEKLKDYQKHIRNFSIVAHVDHGKSTIADRILELTDTVSKRQLKNQMLDDMPLERQRGITIKMNSVQVKYHANDGEDYIFHLIDTPGHVDFSYEVSRSLAACEGAVLVVDASQGVQAQTLSNTYLALENDLEILPVLNKIDLPSADPDMAKSEIGDMLGLDASDAVEVSGKTGAGIPELLERIVTDIPAPTGDLTKPLKALIFDSKYDDYRGVVMSVRIEEGTVKPGDEIMIMNTGKKYEVTEVGVSSPHPVKEDILIAGDVGYITANIKSVRETRVGDTITSAENPTAEALPGYRQIPPMVYSGMYPTDNRDYDDLKEALQKLQLNDASLEFEPETSQALGFGFRCGFLGLLHMDVVQERLEQEFDLDLIMTAPSVDYHAIMPTGEVKLIDNPADLPDAGEYKELQEPYVKAEIMVPNDFVGAVMQLCEGKRGEFQTMDYLDKYRVNVIYEMPLAEIIYDFFDQLKSSTKGYASLDYEIIGYKATNLVKIDILLNKEPIDALSFIAHREEARDRAVQMCSLLKKLIPRQNFQVDIQGAIGSKIISRATIKPYRKDVTWKIHTGDPDRRAKLLEKQKRGKKRMKSVGRVEVLQDAFMAVLRMNDDDINGK
>NZ_CP022988.1|WP_003615401.1|1532021_1532723_-|class-A-sortase
MTSTASKNTKDHPVRRIILRLVAVILFLLGLALVFNQQISAFLVKQNQTAALKGLTRDQVVQNQKKKGMYDFKKVKSIDFAQTTRSRVKNTAGAIGAISIPSVKLYLPVMQGLSDAALSTGGGTMRADQKMGKGNYPLAGHYMTDQGALFSPLERVKLGSMVYLTDLKKVYAYKIYYKKVVDPSAVWLVANTKKKIVTLITCANGGVNRWSLRGKLTAVKPASKQNLEMFKLR
>NZ_CP022988.1|WP_003615400.1|1529748_1532025_-|single-stranded-DNA-specific-exonuclease-RecJ
MKWQERTAAPLASDLVEEFQLSPLTAKLFSLRGIDNEEKIDYWLHASENDLADPFLMHDMDKAVGRINQALDEGEKITIYGDYDADGITATAIMTEMLTIMGADVHYFIPDRFKDGYGPSLDRYKDIVADGTKLIITVDNGVTGIEEVAYAQSHGVDVIVTDHHTFKEEKPDAYALVHCNYPGQAYPFDDYCGAGVAYTIARAVLEDTASEFLELAMIGIIGDMVKVSGEGHVIVKRGLEMLNESSRPGLEALIRNAGLTPGMIDEEDVGFSIAPRLNACGRLADASLAVRLLLAESPGEAQELADQIEKLNNERKDLTQATMQAAEAQIKSRGYQKEATLTLYDPAWHEGVMGLVANKIVEKYHKPTLMLTKNEAGLVKGSGRSSQGFNLFNALKPFEGKSITQFGGHDFACGLSTTEENLNQLRRDFNQSYKAGEKAPEKVQEYDGTISPLDVDLTSVYDLAQAGPFGTDNPQPVFLLDKPQISNFRPMRKGCSFMVGPVRAVDFDHSLNQTVLPYLQQMLVKLASNTFKGKTNVQFRIVDLHYGQSLYVPAARIVDFRGQENLLGFADKYLLFDERNLSQAINHFGITKEQISLAKDNEDLSQQVVSVLDVPANEAQLNFVLAKPYRQLYLRFQLDQLPGETLPSRGNFGLVWQYFLAHPGLKPNDYMQAAGQLGMDPDSIMFILRVFFTLDFVKMEEDRLLPKPSLTKKSLDDSAYYRSVKAEYAFANKLRTISSDELIRYASGLANGGLQNVN
>NZ_CP022988.1|WP_035161317.1|1529231_1529759_-|adenine-phosphoribosyltransferase
MSIDFKKYIASVKDFPNEGIIFRDITPILQDGEAFAAATHEISEYAKSRQADVIVGPEARGFLVGTPVAIELGIGFVPARKPHKLPREVEAAAYDLEYGSNVLEMHKDAIKPGQRVVICDDLMATSGTLHATKELIERLGGKVVGAAFYIELTDLKGREKFPDVDIFSLVQYTGA
>NZ_CP022988.1|WP_003615398.1|1528849_1529152_+|winged-helix-turn-helix-transcriptional-regulator
MTHEELIDQAAHLFKVLGSSLRIHILFYLRKHGESPVSAIVGHLGVSQPVISKQLGILKKHDFVQKRKAGTFVYYSINDQDIVQIIDAMTEHLDHLDRLQ
>NZ_CP022988.1|WP_003615397.1|1527850_1528738_-|cation-transporter
MKDQASKRYLWVTVFNVIITAAEIAGGIISGSLALLSDALHNLSDVVSIVVAFAANLIAKRSKDQHKTFGYKRAETLAAYTNGLFLLAISIYLFISAIKRFSKPEPIEGGVMFIVSLIGLAGNLISMLILGKGSKENLNARALFLNMMSDTLSSVAVAVGSLLIYYQNWTLVDPVLTMAAAIFLLKEAFEVTRDSANVLMEANPDLDLEAIEEAGLAFKEVIQLHHLHVWRYSDDTIMLDAHIVVDSGLTAKRIEELDEEIAACLKEKFAINHVTLQAECSRGLDEDLLSTNKEN
>NZ_CP022988.1|WP_003615395.1|1526623_1527649_-|branched-chain-amino-acid-aminotransferase
MAKKDLDWANIGFGYHQTDKRYVDYFHDGAWEGGKLTDDPNVVLNECAETLQYAQQVFEGMKAYTWKDGSVVVFRPDQNAERMYNSAKRIEMQPYPKDKFVEAIDQVVKGNVDWVPPYGSGATLYLRPYEIGTTPIIGVAPATDYMFRIFATPVGPYYKGGATPVAVQVAQYDRAAPRGTGHVKAALNYAMSLKATVAAHQAGFAENMYLDPATQTYIEETGGSNIIFIDQNNHLVVPKSNSILPSITRRSIVYLAEHYLNLTVEERQVRFDEVPSFKECALVGTAAVLSPVGRIVNGDQVIDMPSGMDKPGKFMEELYNTLTGIQNGEVEAPEGWIHHVM
>NZ_CP022988.1|WP_035182731.1|1525373_1526507_-|AI-2E-family-transporter
MNKFWNHIDQKYFKIALYCLGTVFAGLFILLLAYESTGFWVRVGKILAAIAQPLTYGLVLTYLLLPLTNFFDRKFSKGSSRGAVATASRSAAVALTLLLLLLVILLAATAVFVTFSKQLSHFSLGSLESLYDQLKAQYSSFINEILAYLQKQGWSTSGLVSYMQKGVGRVTGFLSDFFFGMIFAIYFLYDGQRIAAYWKRNLGTLLNKKVIRGIKLFLADADRAFSGYIRGQIIDAFIVGLLVSLAMLIAKVPYGLLIGLVTGLGNLIPYFGPILGYGMVILACTLSQNMTALIVGMIILLLIQAIDGNILNPKLLSSAIHIHPLYVIVCVIAGGAMGGFVGMLIAVPMGALLKTEFERLIAYRQKQLEKSKEASEE
>NZ_CP022988.1|WP_003615389.1|1522837_1525096_+|HAD-IC-family-P-type-ATPase
MKVKGLTQAEADLRLKKDGLNQVPEPEFSFWKEFAGKLWNLSAWILEAALLLECALGKWIQSLFVLLMLLFAAYNGATQKKKSRKVLSSISQQLTPVVAVLRDDRWQKIDSKYLVVGDIVNLQKGDILAADIDLLDGNLTLDESSITGEAKNVHKKAGATAFAGTTVMDGEALGRVSATGTNSRSGQTINLINRSAAPGHLQQLLTKIIYYLCLLDGVLTVILLIAAVIRGENILEMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTSDLTGIQDAANLNLLLLDKTGTITENKTAVASFANFSKLSDEEVLALTSLAIDQRNQSVIDLALMDFLQEKKIPVKEAEAFTPFTSSQGYSEGRGEGHDVKLGSVKQFSKIDPAISEQMAAVDLSLGRSVGILLDDRLAGIFITKDKVRADSKAALAELVKRGIKPVMLTGDNQKTAASVAEEVGLTGKVISISDFKEGVKAEDLAGIADVLPEDKLDMVKYFQKAGYIVGMTGDGVNDSPALKQAEVGIAVSNAADVAKKSSKMVLLDEGLSPIVKILDAGHRVYQRMTTWSLTKLARTAELTMLLTFSYLIFGYLPMALNAMVIYTIMNNMVTMMIGTDKTHITYKPENWDMGKLAKIAFSLAGAWTIIGFAFVSALTKAGVNHDQVGTMVYVFLVMSAMMIVLITRTKRFFWQSAPSKPVASVQIADILLTCLLALLGIAMPAIGIKELLTPLAVAFLAAILIDLVYQPVMKNK
>NZ_CP022988.1|WP_003615387.1|1521805_1522660_-|LysR-family-transcriptional-regulator
MNFKQLNYFLVVAEEGQITSAAKRLFVGQPALSYQLKQLEEELGAKLFIRQPYGIELTEAGKKLRDYAGQILTLAKNVQTEITELDRGGRGRVKLGSVSSSIGELPSAKLTAFARQHPGVSFDIYEDNTFGILDKLQGNLLDLAIVRTPYNRVNLNFVDISDEPMTAVTCQDFFPGKEKVGLQALAGQPLVIYRRFEDMFKEAFAEKGLTPNFVVKCDDSRTAIRWSDSGLGIALVPESIAKTYAKGHIYPIDSAKWRTRLQLVWRKDRVVTPLMRQIIALYAK
>NZ_CP022988.1|WP_003615406.1|1535885_1537730_-|molecular-chaperone-DnaK
MSKVIGIDLGTTNSAVAVLEGKEPKIITNPEGARTTPSVVAFKDGEIQVGEVAKRQAITNPNTIVSIKRHMGESDYKVKVGDKAYTPQEISAMILQYIKKFSEDYLGEPVTDAVITVPAYFNDAQRQATKDAGKIAGLNVQRIINEPTASALAYGLDKDEDDETVLVYDLGGGTFDVSVLQLGDGVFQVLSTNGDTHLGGDDFDNKIIDWLVDGFKQENGIDLSKDKMAMQRLKDAAEKAKKDLSGVSSTHISLPFISAGEAGPLHLEADLTRAKFNELTDDLVQRTKIPFDNALRDAGLSVGDIDKVILNGGSTRIPAVQEAVKQWAGKEPDHSINPDEAVALGAAIQGGVISGDVKDIVLLDVTPLSLGIETKGGVFTKLIDRNTTIPTSKSQIFSTAVDNQPAVDIHVLQGERPMAADNKTLGRFELTDIPAAPRGVPQIQVTFDIDKNGIVNVSAKDLGTGKEQKITIQSASGLSDEEIERMKKEAEEHAEEDAKKKEEVDLRNEVDGLIFQTEKTLKEVDGKLADSDIQPVKDALEDLKKAQKDNNLDEMKEKKDALSKVAQDLAVKLYQQNAQNQQGQGGQAGPTDDGSNGANGDTVDGDFTKVDPDK
>NZ_CP022988.1|WP_003615408.1|1537789_1538389_-|nucleotide-exchange-factor-GrpE
MGKEEFPSEKDLPQEDQEKQAKAAEADKAGVKDDKEEAAKPADVELDQLKAEVAALTQKNKDLEDKYLRSQAEIQNAQRRYSKERANLVKYESQRLGKDILSSVDNLERALQVKADDEASRQLKKGIEMTLEGLVRALKDNGIEEIKADGEKFDPTLHQAVQSVPAENDEQKGHVVQVLQKGYVYKDRVLRPAMVVVAQ
>NZ_CP022988.1|WP_035182733.1|1538423_1539473_-|heat-inducible-transcriptional-repressor-HrcA
MLTERQELILKTIIQDFTKTHEPVGSKTVMNQLSIKVSSATIRNEMAVLEEHGLIEKTHSSSGRVPSTEGYRYYLDNLVQPLQLPEEMYNQIGYQFDQPFNQVDEIVKEAAKILSDLTDYTAFAEGPEAKNVSITGFRIVPLAPRQVMAILVTSDGSVKNQLYTLPRHISGDEVEQAVRLINDKLVGKNLSEINKQTFEQLSSSQIVGKNTPEFLELLEAVIKDAASEQMYVDGLLNLLNNTENSDLKAIKSLYELINSSSLAGELIDLSDSPSHYPVYVRLGAELENDLLKDFSLVMAEYSVGRYGRGTIALLGPRHMPYSEMIGLMEYFRQELARKLLDYYGRFKCC
>NZ_CP022988.1|WP_003615411.1|1539608_1540550_-|riboflavin-biosynthesis-protein-RibF
MKVINLSYPFKKELTAGKVVLALGFFDGVHIGHQKLIKEARIIAVEKDLPLMVLTFDRHPKEVYAGVKDFEYLNTPEEKAYEMSKIGVDYLVILKFTPEFSHLAPQAFVDEIIMGLKADTVVAGFDYSYGPKDVANMENLPAFAKGRFDIKVVPKQIFAGKKIGSTEIRQAVKSGNLRLATELLGHPYLTSGKVVHGFRNGHKLGFPTANLELDWPKVLPKIGVYATMTQVGDRWYQSMTSVGYNVTFNDEKKIYIESNIFDFDQDIYGQQITIAWYKYLRGEEKFADMAALSEQLKLDQVASENYFSSLIEQ
>NZ_CP022988.1|WP_080553976.1|1540663_1541257_-|site-specific-integrase
METFLNGARDVGMMKYTLFRLLAFSGMRIGELIALEWSDVDFASQSVSINKTLTLDKYGQATVGSPKTTNSNRAVLLDDVTMTILRQWRAEHARRIIYFGKPRNNLVFASEHGGHLSNGTIKGWNKKIAENKGLRAISLHGFRHTHASLCFEAGLTMQDVKERLGHSSISTTVDIYTHVTNDRKEESVQQLAKFMRA
>NZ_CP022988.1|WP_052109142.1|1542764_1543181_-|Arm-DNA-binding-domain-containing-protein
MNKKDIIKYQTASGKDRYKFIVYAGKDETTGKSIIIRKQGFKTLKEAKQAYLDVQQAILNGDYLPINQKRLTFKGLLELYLPLYAQTVKETSFYQFKRCMESKVLPVLGDVYLDKITPQLCQKAVNQWARERPKSGTV
>NZ_CP022988.1|WP_095439278.1|1544049_1544844_+|transposase
MAQSKGTDVVIQLLDQALKAGLTAKYVMFDTWFSNPHQIVQISQRGLNVIAMVKKSSKITYEFEGKRMTVKQILNACKKRRGRSRYLLSVPVKVGDPAKDGAQIDARIVCVRNRSNRKDWIALICTDMTIDENEIIRIYGKRWDIEVFFKTCKSFLKLGTEYHGLSYDALTAHTAFVFLRYMFMSVEKRDDEDDRTIGELFYCMVDELADITFNHSLQILVEAMFESVKEIFPPTEEQMERFTKAFIPRLPKYMQEALTPSLAA
>NZ_CP022988.1|WP_003615418.1|1546141_1547053_+|cysteine-synthase-family-protein
MLIHSISELIGHTPLIDLQINIPNHSHIYAKLEMFNPGGSIKDRLGQYMIQDAINRGQITEGVTTIIEPTAGNTGIGVALAARQHHLPTILVVPEKFSFEKQQLMKALGAKLINTPSDQGIKGAIEKAEALHDQTPNSFVPMQFKNPANPDTYYHTLAPELLDDLNDPIDAFVAGAGSGGTFAGVACYLKEQNPATQTIVVEPEGSILNGGPAHPHRTEGIGVEFVPPFFKDVQIDKTLTIADADAFHQVKELAKKQGLFIGSSSGAALAASLKVAKALPENSTIVTIFPDSSERYMSENIYN
>NZ_CP022988.1|WP_003615419.1|1547074_1548259_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MEFDTKLIHGGISEDKATGAVSVPIYMASTFHQQKIGENQYEYSRSGNPTREAVEKLIAELEGGTAGFAFASGSAAIDTVFSMFSAGDHFIIGNDVYGGTFRLIDAVLKRFGMTFTVVDTRDLAAVEEAITPNTKAIYLETPTNPLLRVTDIAAVAKIAKSHQILSIIDNTFSSPYIQRPLEQGVDIVLHSASKYLGGHSDVIAGLVVTKDDQLAEKIGYLQNAIGGILAPQESWLLQRGIKTLSLRMRAHLANAEAVFNYLSNQPLVSKIYYPGDPNNPDYEVAKKQMHGFGAMISFELQDGLDPKQFVEQLHVITLAESLGALESLIEIPALMTHGSIPRDIRLKNGIKDELIRLSVGVEDQKDLLADLERGFNELKRSEKNVSDSKVHSQA
>NZ_CP022988.1|WP_003615420.1|1548224_1548782_+|serine-acetyltransferase
MFQTARSILKRDPAAHSLLEVLLTYPGIRALFWYRIAHFMAFHRLYTIAGFLSQHAAKVTGISISPEAQIGKRVFIDHGIGVVIGATAVIEDDVTILHGVTLGARRAVEGRRHPYVKKGAFIGANAQLLVTITIGAFSKVGAGAIVLNNVADKTTVVGNPARTVNKLPAKVINVTFTTNTSTTKN

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Crispr_ID: NZ_CP022988_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022988_5

2052663-2052767

Orphan

Consensus_repeat	Method
GTGGTATAATAGTTGGCGTAGGGGAGTGAGAACGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022988_5

>merge|NZ_CP022988|5|2052663-2052767|CRISPRCasFinder
GTGGTATAATAGTTGGCGTAGGGGAGTGAGAACGATGAAGATCAATAATTCTTCGATACCTCGACGACAGTGGTATAATAGTTGACGTAGGGGAGTGAGAACGAT

>NZ_CP022988|5|4|2052663-2052767|CRISPRCasFinder
GTGGTATAATAGTTGGCGTAGGGGAGTGAGAACGAT	GAAGATCAATAATTCTTCGATACCTCGACGACA
GTGGTATAATAGTTGACGTAGGGGAGTGAGAACGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022988.1\|WP_003616510.1\|2047746_2049237_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_CP022988.1\|WP_003616492.1\|2062973_2063171_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP022988.1\|WP_003616508.1\|2049405_2050164_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|379135
NZ_CP022988.1\|WP_003616516.1\|2043347_2044928_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP022988.1\|WP_035182879.1\|2067192_2068068_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|283645
NZ_CP022988.1\|WP_003613167.1\|2037757_2039161_-\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NZ_CP022988.1\|WP_035172677.1\|2061834_2062032_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022988.1\|WP_003616489.1\|2063705_2063948_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP022988.1\|WP_003616523.1\|2041614_2041854_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371212
NZ_CP022988.1\|WP_080553986.1\|2058263_2058977_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|225109
NZ_CP022988.1\|WP_003616481.1\|2068060_2069371_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
NZ_CP022988.1\|WP_003616476.1\|2075191_2075461_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP022988.1\|WP_057727112.1\|2040641_2041556_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022988.1\|WP_003617868.1\|2059073_2059928_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|283235
NZ_CP022988.1\|WP_003616503.1\|2051902_2052571_+\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|225974
NZ_CP022988.1\|WP_148465380.1\|2040146_2040371_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022988.1\|WP_003616522.1\|2041950_2042451_-\|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl\|CDD\|394878
NZ_CP022988.1\|WP_003614608.1\|2057420_2058089_-\|IS607-family-transposase	unknown	unknown	gnl\|CDD\|239738
NZ_CP022988.1\|WP_003613384.1\|2066318_2067128_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_CP022988.1\|WP_003616531.1\|2039678_2039903_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022988.1\|WP_003616510.1\|2047746_2049237_-\|IS1182-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.23804e-19
NZ_CP022988.1\|WP_003616492.1\|2062973_2063171_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	8.85016e-33
NZ_CP022988.1\|WP_003616508.1\|2049405_2050164_-\|tyrosine-protein-phosphatase	gnl\|CDD\|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	4.9492e-64
NZ_CP022988.1\|WP_003616516.1\|2043347_2044928_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.31513e-62
NZ_CP022988.1\|WP_003613167.1\|2037757_2039161_-\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP022988.1\|WP_003616489.1\|2063705_2063948_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	6.44086e-22
NZ_CP022988.1\|WP_003616523.1\|2041614_2041854_-\|hypothetical-protein	gnl\|CDD\|371212	pfam10726, DUF2518, Protein of function (DUF2518). This family is conserved in Cyanobacteria. Several members are annotated as the protein Ycf51. The function is not known.	0.00889245
NZ_CP022988.1\|WP_080553986.1\|2058263_2058977_+\|diguanylate-cyclase	gnl\|CDD\|225109	COG2199, COG2199, c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms].	2.39524e-17
NZ_CP022988.1\|WP_003616481.1\|2068060_2069371_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	8.82099e-29
NZ_CP022988.1\|WP_003616476.1\|2075191_2075461_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	1.78435e-08
NZ_CP022988.1\|WP_003617868.1\|2059073_2059928_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|283235	pfam05525, Branch_AA_trans, Branched-chain amino acid transport protein. This family consists of several bacterial branched-chain amino acid transport proteins which are responsible for the transport of leucine, isoleucine and valine via proton motive force.	5.69592e-64
NZ_CP022988.1\|WP_003616503.1\|2051902_2052571_+\|cobyric-acid-synthase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	8.202e-73
NZ_CP022988.1\|WP_003613384.1\|2066318_2067128_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	8.86944e-72
NZ_CP022988.1\|WP_003614608.1\|2057420_2058089_-\|IS607-family-transposase	gnl\|CDD\|239738	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.	5.95062e-55
NZ_CP022988.1\|WP_035182879.1\|2067192_2068068_-\|alpha/beta-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	1.91426e-58
NZ_CP022988.1\|WP_003616522.1\|2041950_2042451_-\|O-acetyl-ADP-ribose-deacetylase	gnl\|CDD\|394878	cd02908, Macro_OAADPr_deacetylase, macrodomain, O-acetyl-ADP-ribose (OAADPr) family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. This family includes eukaryotic macrodomain proteins such as human MacroD1 and MacroD2, and bacterial proteins such as Escherichia coli YmdB; these have been shown to be O-acetyl-ADP-ribose (OAADPr) deacetylases that efficiently catalyze the hydrolysis of OAADPr to produce ADP-ribose and free acetate. OAADPr is a sirtuin reaction product generated from the NAD+-dependent protein deacetylation reactions and has been implicated as a signaling molecule. By acting on mono-ADP-ribosylated substrates, OAADPr deacteylases may reverse cellular ADP-ribosylation.	2.18281e-94

>NZ_CP022988.1|WP_003616503.1|2051902_2052571_+|cobyric-acid-synthase
MDDNLIRIAYLYEDLMNTYGDSGDVKILRYFLQKKGWQTQIDNISLGSQFNAADYDFVFFGGGQDYEQSIVAKDLQRFKETLNDYIQAGNPMLAICGGYELMGTYYNTISGAKIKGLGILPLHTEFDPEKRMIGDTKYETEWGPTIGFENHSGQTFLDDRKMLKPFAKVVEGYGNNHEEKEDGVRYKNFIGSWSHGPMLKNENVANALVDMILKRHAARVAQ
>NZ_CP022988.1|WP_003616508.1|2049405_2050164_-|tyrosine-protein-phosphatase
MPKRIVKLEAGYNCRDLGGYVSQDGRTVKWGRLYRSGSLSHLTKADQAELARRKIVVDCDLRSRHEQDNFPDKLWPGAKLVDAHFYSESGDEEEEAEAAWEKYSGKLPKLSYLAMVYQQNLVAPRTGLVMRKIFKEMLTLEDDEALIYHCSMGKDRTGMVSVIVLMALGLGDREILRDYLLSREYSQDWDKADENDRLGQQIAKMNQTQVSQTAFYGITETIRQTWGGFDRYFASLGFGQGDLDRLRDKFLE
>NZ_CP022988.1|WP_003616510.1|2047746_2049237_-|IS1182-family-transposase
MYKYYNTDRSQLTIRLESVVPQNHLVHLIDSFVDTIPLDDLLKNLANTGRPAYHPALLLKILLFAYSGRTFSGRKIELMLQESLPMMWLARNERISYHTINNFRSSDEANMLVKRAFLYFTQMLIDENLIRENALFIDGTKLEEDANKYSFVWRKAVEKYHDKLKNHALELYDELVKENVTQTIEREQAQEAAGLEEIAKSTEAKIEKLTEEIDSENLDKTEKSARKQLRRKLKKIARKLHKDYIPRAYKYEQSEKIFQGRNSYSKTDHDATFMLMKEDHMRNGQLKPGYNIQAVTSNQYVIDYAIFPNPTDTRTLVPFLSQMALLSHFENIVADTGYGSEYNYITLEDQFKKKYYIQYSTYRIEKTRKYKKDPTKVANWHYDEADDFYIDPQGVRFRFKGYSSKVDRYGYKRDFKIYEADPIQETDELEEASKTPKGYQRRITYNPTWENVKAHAKEYLESEDGKRIYSYRKIDVEPIFGHLKNVFEFTSAEGRK
>NZ_CP022988.1|WP_003616516.1|2043347_2044928_-|ABC-transporter-ATP-binding-protein
MKIGELVRQNRLRFTCALALEVLGQLCVAVGNYIIGFILDLLVKRDISRFYLVLAVFFVLYMGGYVLISFAEYLYIVQVQEYVHQLRRKTVDYYYQNSETVAEMQNHLTNDFQMLFDNFTQPLFVFFDSALAVVFSAYALITMHWILLVTTVLLSVMFLYLPSIFSKKYQERTLNFSNMNTAYLTSIKNWLGGLAEIQRYDARHKLVEVLEKRSKKLEGSLVTRQVSAIEINFINGFMSIFCQVVLDLVTGALIFAGAISIGKLVAVGQFSSTIFNSLVTLSNYLEQIKSTKPLNEKVAAALADPPKDVNTDKELASFDHLQTTGLSFSYDHGETINYPDLKIKAGEKVLLTGDSGTGKSTLLKVLAGELKATTGNIAFYDHNDRKIDISLKAMHYVPQDPVLFPASIADNITMFKLELNDKVGEYLQKVDLAKDIAKFPKGQDTVIDVEKLNVSGGQRQKIVLARAELNQSDFILIDEATAAVDQDSTKRILKNLLKTNATIIFIGHNFTNEMVDMFDRQIFLSK
>NZ_CP022988.1|WP_003616522.1|2041950_2042451_-|O-acetyl-ADP-ribose-deacetylase
MNLEIWQGDITTLKVDAIVNAANRELRGGGGVDGAIHRAAGPELNEACRALGSCETGEAKITPGFNLPAKYIIHTVGPIYSGSHSDPLLLAACYRNSLRVAKENGLHSVAFSAISTGVYGYPLDAASKVAFGEVRKWLREHKDYEIRVIMVAYDARTYALYQKLLG
>NZ_CP022988.1|WP_003616523.1|2041614_2041854_-|hypothetical-protein
MLRKYYVTIVFTLLALLNLLSSWGTLQYRLVMLALNLVCGFSMEYLVNKKAPAEKYNLWKGCTAAVLLAVNLLWIFLTK
>NZ_CP022988.1|WP_057727112.1|2040641_2041556_+|hypothetical-protein
MARMSRRQYQERQEQTAQKQTRQTNPNSVPRLDTDGASRSEQKVRLNFWQIFADRPYVTVIMISLALFCILAKWWIGLAIIIILTIAGIFVIGRSHHPNRVLSLEFKLKASRKLSMIKALQLLGSNIMFLAAYMRQIVSVDFSSAGATDSLTVIQNMLSNQGTFDQQGSYFLNLFNQLTGGSLWGIYRYATNSSQMMNSTAGTMIILWIFLLMIAPAFCVLSQFFREPYSRHVMTVASLISTISFALTPTLMNRWVISYAVENQMSQAAAENAVQVGGMVYPAIISAIFVFILAIYREIKKDEF
>NZ_CP022988.1|WP_148465380.1|2040146_2040371_-|hypothetical-protein
MKARSETWIKQMAAVAAAGIGAVSLGAVNLPQPVNAATNDVQARSSQDDLKTAQENVKTAEAAKRASCFDRGGS
>NZ_CP022988.1|WP_003616531.1|2039678_2039903_-|LPXTG-cell-wall-anchor-domain-containing-protein
MTVVNTDEEPATKSAAKTPTLVTKLANTAPAATGAQLPQTGEKDAKPGILAGIISLLAGVSLFGFSFEKRKQEK
>NZ_CP022988.1|WP_003613167.1|2037757_2039161_-|class-II-fumarate-hydratase
MAEQEYRIESDTIGEVKIPKEALWGPQTERSRNNFPSGELMPLAIIRAFLHLKKAAAESNVEVGDEPAEKGQAIEEAIDQLLALSDEDLRKDFPLHVLQTGSGTQTNMNVNEVVANLANKLHPGLNILPNDDVNRGQSSNDTYPTAMNIVAVEAVDKLEPAIEHLIDELKVKQDKYWKTVKVGRTHLQDATPLTFGQEVSGYISALKHDLAYIQELKPSLYELAIGGTAVGTGLNAAPGMTEAIAGKLSEVYGHEFKVDTNKFWGLAHHSALSVMHGAFKTLANDMFKIAQDIRFLASGPRAGYGELNIPANEPGSSIMPGKVNPTQAEAVTMAVARVLGNDVTINFAASQGNFEMNVFKTVMIAAFLESADILAGTITGFADKMIHGLTVNEQRMDDLLENSLMTVTALSPKIGYHEAAVIAQTAQREGTTLKEAALKSGKVTEEQYDEWMDYMAMTNIDRTKPEE
>NZ_CP022988.1|WP_003614608.1|2057420_2058089_-|IS607-family-transposase
MAEEYLGIKDAAKYLKVSISTLRRWEKKGLITPMRTAGNRRRYTVRQLDDMLGLNTQKELGAVARRGLVIGYCRVSSSGQKADLERQAEVVANYCEKQGYQFRIIKDIGSGMNYKKKGLQELLRLVCEGGCSKIVVNYKDRLVRFGYELIETVCEEHNVDIEIINQTDDISYEEELTEDVLAIITVFSAKLYGKRSHRNEQIVAENRKLFSKDDKKETKDSN
>NZ_CP022988.1|WP_080553986.1|2058263_2058977_+|diguanylate-cyclase
MQPENLWDAITHQIKLSVFWKDRQRNFPGANQHFLDYYGLTLLEVIGHNDDKLGLNVHPENFQESEMQLLEDGGPVKERGKTRSRGRIREIMILKAPVYDQDQIVGLIGFFMDITNTSKQINRLENEAARDDLTSLKNRHNFARDFNYLTGKPILAMMLDVDHFKKFNDNFGHRYGDEVLKKISQALLKIYGIGHCYTGTGATNSWCSATLLILTRLRKKTGSSGKNWNMPGSWTST
>NZ_CP022988.1|WP_003617868.1|2059073_2059928_-|branched-chain-amino-acid-transport-system-II-carrier-protein
MGATSSTQASADYLAAPLTNGFLQGYNTLDALAALDFGITVVTAIKGFKIKEGKETSLALAKTGAIGFAGIAIIYLILILVALGAGSLHYFKLSENGGIAFAQIVHHYLGTFGEALLATLATITCMSTAIGLVVAFAQDSHKRFPKISYRTFLTFNCLLSFAIANFGLTTIIAWSTPVLMFLYPLAIALIFCGLTSNFFNNDTAVYKFVVYFTIIPAIFDGLNASPSIISNTAFAKAALTFAGRYLPQKIQRESKLSFHAVSFYSYSKNSAGKGCRRCPCGRSF
>NZ_CP022988.1|WP_035172677.1|2061834_2062032_+|hypothetical-protein
MKNKILGNKLFKSGKVLIAVAGVSVIMTNAVIPVISTASANTNKVTPVHTASNWRANDQKPLIIT
>NZ_CP022988.1|WP_003616492.1|2062973_2063171_+|cold-shock-protein
MQNGTVKWFNADKGFGFITGSDGDVFVHFSSIKTNGFKSLEEGQKVSYDVEQGNRGPQATNVVPQ
>NZ_CP022988.1|WP_003616489.1|2063705_2063948_+|recombinase-family-protein
MALKDVDKLFTDKLSGANTNRPELKKMLAYIREGDIVMVTELDRLGRNNQDLTNSLASKYSIKLLVMALMPPACTSGGGK
>NZ_CP022988.1|WP_003613384.1|2066318_2067128_-|Cof-type-HAD-IIB-family-hydrolase
MKIKLIAVDLDGTLLTSRKKVSPKTLATLKKAREKGILVVPLSGRPLPGVLKVFEPFKLDPADNFAICYNGGLIQRMDGEVLSASPLTDENVEHILALKQTGIFGPYFMDTKDFYVAPKGSAFGVGFLAKARNMGVKRMVPGQHYEFIKGEFVSLPSKMKKFRAGFSPATEQEFEISASGGHCLEFNTPGTSKGQALTTLLDLLNIQPEEAMVFGDNNNDLSDFQLPGVFKVAMGNAIDEIKAAADYVTASNNQDGIALAVEKFVDMGE
>NZ_CP022988.1|WP_035182879.1|2067192_2068068_-|alpha/beta-hydrolase
MFKSRNWKLIVVALTIIILLAVPGYSWMKKTNKEHAERQRSQLSPLIMVPGSSATVNRFNELVDLLNENTPYKHSLLKVEISEDGTLTYSGSIKEEDNEPFIVIGFQNNHDGYSNIKKQAGWLDDAFYEIAKTYKFNNFKAFGHSNGGLIWTYWLEHYYSDYSDEITIKRLMTLGSPYNFSEKSIKYKTQMMTDFIKYRKRLPKNMIVYSLSGGKNYESDGIVPESSVEAGKYIFQNQVKSYTTMTVTGAEAQHSSLPQNKQVVRIIQEYLLKQQVKPGPNNSQNSKHKEN
>NZ_CP022988.1|WP_003616481.1|2068060_2069371_-|PTS-sugar-transporter-subunit-IIC
MDKLAKWCIWLSRRSFFRVAQRTFAVLMPIATVGAFFQVLQNSVFAPESFIYNLFDFDKIMSDRFWDIGTSLSQCVVEVIFGLFCLFTVYFSASFTAKIYRKDATMAGISALTSLLVMIYLFQLGLTGRISLLTGGYLVFQYTFFALLLGYGVGQVFHWLGADYEPVNYEHTKLVQDRAIKALKPTLVTVIVGIAIGGILYVVISKVKANFSLTRIVSSVENSNNLLLTVPATALASFLSWLGLEAPILDLGNVAGSAAATANLTYVLRRGSVWKVPYPYLGGSMISIYGVMGGCGTILALAVAILIWGRRKESETVAKMNLWPLLFSSSRGFLVGLPVILNPIYALELVLVPVVNMLIAALAIFLHIVPTPVYTVLTGTPGPLVPFFATNGNWPTLIFTIFLFCLDVVMMIPAVKLDNRTKILLKDYEMEDDRHV
>NZ_CP022988.1|WP_003616476.1|2075191_2075461_-|anion-permease
MINQIYHAGFLSIALGAGVPKIMAALILAFCGSVFLSTSTYSAGPAAMLSGTGYVSNKGWRKLSAIIGVIFNVIWLGGGLLWTKCIGYW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP022988_1	1.5\|284915\|18\|NZ_CP022988\|CRT	284915-284932	18	NZ_CP022988.1	1622249-1622266	1	0.944
NZ_CP022988_1	1.6\|284951\|18\|NZ_CP022988\|CRT	284951-284968	18	NZ_CP022988.1	1622249-1622266	1	0.944
NZ_CP022988_1	1.7\|284987\|18\|NZ_CP022988\|CRT	284987-285004	18	NZ_CP022988.1	1622249-1622266	1	0.944
NZ_CP022988_1	1.4\|284879\|18\|NZ_CP022988\|CRT	284879-284896	18	NZ_CP022988.1	2025787-2025804	2	0.889

1. spacer 1.5|284915|18|NZ_CP022988|CRT matches to position: 1622249-1622266, mismatch: 1, identity: 0.944

gctgcaaagaaggcaacc	CRISPR spacer
gctgcaaagaaggcagcc	Protospacer
***************.**

2. spacer 1.6|284951|18|NZ_CP022988|CRT matches to position: 1622249-1622266, mismatch: 1, identity: 0.944

gctgcaaagaaggcaacc	CRISPR spacer
gctgcaaagaaggcagcc	Protospacer
***************.**

3. spacer 1.7|284987|18|NZ_CP022988|CRT matches to position: 1622249-1622266, mismatch: 1, identity: 0.944

gctgcaaagaaggcaacc	CRISPR spacer
gctgcaaagaaggcagcc	Protospacer
***************.**

4. spacer 1.4|284879|18|NZ_CP022988|CRT matches to position: 2025787-2025804, mismatch: 2, identity: 0.889

gatgcaaagaaggcaacc	CRISPR spacer
gatgcaaagaatgtaacc	Protospacer
*********** *.****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022988_3	3.4\|1150999\|35\|NZ_CP022988\|PILER-CR,CRISPRCasFinder,CRT	1150999-1151033	35	CP031025	Lactobacillus phage ViSo-2018b, partial genome	31676-31710	0	1.0
NZ_CP022988_3	3.5\|1151067\|33\|NZ_CP022988\|PILER-CR,CRISPRCasFinder,CRT	1151067-1151099	33	NC_022775	Lactobacillus phage phiJB, complete genome	6592-6624	0	1.0
NZ_CP022988_3	3.6\|1151133\|34\|NZ_CP022988\|PILER-CR,CRISPRCasFinder,CRT	1151133-1151166	34	EF455602	Lactobacillus phage LL-H, complete genome	12039-12072	1	0.971
NZ_CP022988_3	3.3\|1150933\|33\|NZ_CP022988\|PILER-CR,CRISPRCasFinder,CRT	1150933-1150965	33	EU409559	Lactobacillus phage JCL1032, complete genome	15926-15958	3	0.909
NZ_CP022988_1	1.1\|284747\|30\|NZ_CP022988\|CRT	284747-284776	30	MN855971	Bacteriophage sp. isolate 354, complete genome	6509-6538	5	0.833
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	MN855764	Siphoviridae sp. isolate 508, partial genome	16999-17028	5	0.833
NZ_CP022988_3	3.8\|1151266\|34\|NZ_CP022988\|PILER-CR,CRISPRCasFinder,CRT	1151266-1151299	34	NZ_AP018720	Sterolibacteriaceae bacterium J5B plasmid pSTJ2, complete sequence	65038-65071	5	0.853
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	MN693172	Marine virus AFVG_25M378, complete genome	13852-13881	7	0.767
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	NC_011038	Yersinia phage Yepe2, complete genome	25584-25613	8	0.733
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	JQ965702	Yersinia phage YpP-G, complete sequence	25736-25765	8	0.733
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	HQ333270	Yersinia phage Yep-phi, complete genome	25514-25543	8	0.733
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	NC_008694	Yersinia phage Berlin, complete genome	25497-25526	9	0.7
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	MT374859	Yersinia phage vB_YpP_T3, complete genome	25918-25947	9	0.7
NZ_CP022988_1	1.3\|284831\|30\|NZ_CP022988\|CRT	284831-284860	30	AM183667	Bacteriophage Berlin complete genome	25497-25526	9	0.7

1. spacer 3.4|1150999|35|NZ_CP022988|PILER-CR,CRISPRCasFinder,CRT matches to CP031025 (Lactobacillus phage ViSo-2018b, partial genome) position: , mismatch: 0, identity: 1.0

gcttaacctggtcactctccgtgatctctatcagc	CRISPR spacer
gcttaacctggtcactctccgtgatctctatcagc	Protospacer
***********************************

2. spacer 3.5|1151067|33|NZ_CP022988|PILER-CR,CRISPRCasFinder,CRT matches to NC_022775 (Lactobacillus phage phiJB, complete genome) position: , mismatch: 0, identity: 1.0

cacaatcatagaacttgaagcttgaatcgcctt	CRISPR spacer
cacaatcatagaacttgaagcttgaatcgcctt	Protospacer
*********************************

3. spacer 3.6|1151133|34|NZ_CP022988|PILER-CR,CRISPRCasFinder,CRT matches to EF455602 (Lactobacillus phage LL-H, complete genome) position: , mismatch: 1, identity: 0.971

tttaaagacatggttacccaggcgaccgagtctt	CRISPR spacer
tttaaagacatggttacccaggcgaccgagtcct	Protospacer
********************************.*

4. spacer 3.3|1150933|33|NZ_CP022988|PILER-CR,CRISPRCasFinder,CRT matches to EU409559 (Lactobacillus phage JCL1032, complete genome) position: , mismatch: 3, identity: 0.909

cgtctaaaggtttgatgcagaccattgggccaa	CRISPR spacer
catctaaaggtttgatgcaaactattgggccaa	Protospacer
*.*****************.**.**********

5. spacer 1.1|284747|30|NZ_CP022988|CRT matches to MN855971 (Bacteriophage sp. isolate 354, complete genome) position: , mismatch: 5, identity: 0.833

agcactaagaagagcactaagaaggctgca	CRISPR spacer
aacgcaaagaagaacactaagaaggcttca	Protospacer
*.*.* *******.************* **

6. spacer 1.3|284831|30|NZ_CP022988|CRT matches to MN855764 (Siphoviridae sp. isolate 508, partial genome) position: , mismatch: 5, identity: 0.833

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
gttgctaagaagtcaactaagaaagctgac	Protospacer
*.*** *****************.***. *

7. spacer 3.8|1151266|34|NZ_CP022988|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018720 (Sterolibacteriaceae bacterium J5B plasmid pSTJ2, complete sequence) position: , mismatch: 5, identity: 0.853

-ggtcatgctgaggatggtgtagtagccggtggca	CRISPR spacer
tgggcaggc-gaggatggtgcagtggccggtggca	Protospacer
 ** ** ** **********.***.**********

8. spacer 1.3|284831|30|NZ_CP022988|CRT matches to MN693172 (Marine virus AFVG_25M378, complete genome) position: , mismatch: 7, identity: 0.767

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
actgcaaagaagactactaagaagaaaact	Protospacer
.*********** * *********.  **.

9. spacer 1.3|284831|30|NZ_CP022988|CRT matches to NC_011038 (Yersinia phage Yepe2, complete genome) position: , mismatch: 8, identity: 0.733

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
ttcgatagcaagtcgactaagaaggctacc	Protospacer
 ..*  *. *****.***************

10. spacer 1.3|284831|30|NZ_CP022988|CRT matches to JQ965702 (Yersinia phage YpP-G, complete sequence) position: , mismatch: 8, identity: 0.733

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
ttcgatagcaagtcgactaagaaggctacc	Protospacer
 ..*  *. *****.***************

11. spacer 1.3|284831|30|NZ_CP022988|CRT matches to HQ333270 (Yersinia phage Yep-phi, complete genome) position: , mismatch: 8, identity: 0.733

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
ttcgatagcaagtcgactaagaaggctacc	Protospacer
 ..*  *. *****.***************

12. spacer 1.3|284831|30|NZ_CP022988|CRT matches to NC_008694 (Yersinia phage Berlin, complete genome) position: , mismatch: 9, identity: 0.7

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
ttcgatggcaagtcgactaagaaggctacc	Protospacer
 ..*  .. *****.***************

13. spacer 1.3|284831|30|NZ_CP022988|CRT matches to MT374859 (Yersinia phage vB_YpP_T3, complete genome) position: , mismatch: 9, identity: 0.7

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
ttcgatggcaagtcgactaagaaggctacc	Protospacer
 ..*  .. *****.***************

14. spacer 1.3|284831|30|NZ_CP022988|CRT matches to AM183667 (Bacteriophage Berlin complete genome) position: , mismatch: 9, identity: 0.7

gctgcaaagaagtcaactaagaaggctacc	CRISPR spacer
ttcgatggcaagtcgactaagaaggctacc	Protospacer
 ..*  .. *****.***************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

19014 : 77717

Bacillus_phage(14.29%)

transposase,integrase

attL 21890:21949|attR 84580:85947

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439300.1\|19014_20277_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_035162072.1\|20476_21310_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
21890:21949	attL	NA	NA	NA	NA
WP_095439197.1\|22016_23195_+\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	7.2e-24	28.3
WP_003616373.1\|24108_24414_-	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_003616370.1\|24875_25514_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.6e-20	33.3
WP_003616369.1\|25510_26278_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_003616368.1\|26280_26526_+	hypothetical protein	NA	NA	NA	NA
WP_003616367.1\|26746_27901_-	SLAP domain-containing protein	Q38317	Lactobacillus_phage	3.6e-60	56.7
WP_002880554.1\|28161_28683_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003616366.1\|28962_29739_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_003616364.1\|29774_30332_+	ECF transporter S component	NA	NA	NA	NA
WP_035182862.1\|30358_33124_-	DEAD/DEAH box helicase	Q9T1H9	Lactobacillus_phage	2.1e-26	26.3
WP_003616362.1\|33272_33983_+	DUF975 family protein	NA	NA	NA	NA
WP_003616361.1\|34071_34551_+	YcxB family protein	NA	NA	NA	NA
WP_003616360.1\|34642_35071_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_003616358.1\|35209_36055_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_002880537.1\|36133_36322_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_003616356.1\|36789_37362_+	hypothetical protein	NA	NA	NA	NA
WP_003616354.1\|42971_43319_+	hypothetical protein	NA	NA	NA	NA
WP_035183044.1\|43672_44635_+	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_003616351.1\|44674_45550_+	ROK family protein	NA	NA	NA	NA
WP_003613533.1\|45769_46213_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	1.1e-25	44.2
WP_003616350.1\|46235_47414_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q5ULQ4	Lactobacillus_virus	9.5e-109	53.3
WP_003613541.1\|47375_47579_-	hypothetical protein	NA	NA	NA	NA
WP_003616349.1\|48185_48950_+	hypothetical protein	NA	NA	NA	NA
WP_002880600.1\|48946_49729_+	hypothetical protein	NA	NA	NA	NA
WP_035182858.1\|49779_50265_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_035170660.1\|50692_51412_-	aquaporin family protein	A0A1J0F964	Only_Syngen_Nebraska_virus	4.6e-21	32.4
WP_003616344.1\|52669_54112_+	sucrose phosphorylase	NA	NA	NA	NA
WP_095439300.1\|54239_55502_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_095439198.1\|57512_58562_-\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	1.1e-52	35.2
WP_003613545.1\|60640_61588_+	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	1.9e-75	47.6
WP_003616342.1\|63303_63507_+	hypothetical protein	NA	NA	NA	NA
WP_003616341.1\|63549_66045_+	phage/plasmid primase	A8ATF3	Listeria_phage	8.0e-73	28.7
WP_003616340.1\|66689_66920_-	hypothetical protein	NA	NA	NA	NA
WP_080553966.1\|69163_69547_+	hypothetical protein	NA	NA	NA	NA
WP_003616336.1\|70264_70522_-	DUF5320 domain-containing protein	NA	NA	NA	NA
WP_095439199.1\|70680_72048_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_157737562.1\|72166_73255_+	AlwI family type II restriction endonuclease	A0A2K5B262	Erysipelothrix_phage	3.0e-16	25.5
WP_011544347.1\|73317_73542_-	hypothetical protein	NA	NA	NA	NA
WP_095439200.1\|73513_75265_-\|transposase	transposase	NA	NA	NA	NA
WP_003616334.1\|75685_76153_-	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_003616333.1\|76789_77443_+\|integrase	phage integrase N-terminal SAM-like domain-containing protein	NA	NA	NA	NA
WP_080553965.1\|77339_77717_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
84580:85947	attR	NA	NA	NA	NA

DBSCAN-SWA_2

83333 : 141917

Ralstonia_virus(21.05%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439197.1\|83333_84512_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	7.2e-24	28.3
WP_003616324.1\|84673_85180_-	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_003616322.1\|85345_86179_+	DegV family protein	A0A1X9I5J4	Streptococcus_phage	4.6e-41	37.9
WP_035182853.1\|86440_87025_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_003616319.1\|87021_87675_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_003616318.1\|87750_88578_+	hypothetical protein	NA	NA	NA	NA
WP_035160836.1\|88937_89129_+	hypothetical protein	NA	NA	NA	NA
WP_035183031.1\|89672_90113_+	hypothetical protein	NA	NA	NA	NA
WP_016396016.1\|90090_90363_+	hypothetical protein	NA	NA	NA	NA
WP_003616311.1\|91234_91780_-	biotin transporter BioY	NA	NA	NA	NA
WP_002879656.1\|92177_92891_+	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_003616310.1\|92940_93099_+	hypothetical protein	NA	NA	NA	NA
WP_003616308.1\|93156_93984_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	5.3e-98	62.6
WP_002879652.1\|94063_94603_+	hypothetical protein	NA	NA	NA	NA
WP_095439201.1\|96439_97807_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	7.1e-31	29.1
WP_095439201.1\|97908_99276_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	7.1e-31	29.1
WP_002879651.1\|99433_100342_+	L-lactate dehydrogenase	NA	NA	NA	NA
WP_016396011.1\|100460_101318_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.6e-51	41.1
WP_003616305.1\|101613_103833_+	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent	W0LIV6	Mycobacterium_phage	7.3e-86	32.8
WP_003616304.1\|103897_104347_+	DUF4430 domain-containing protein	NA	NA	NA	NA
WP_003616303.1\|104348_104897_+	ECF transporter S component	NA	NA	NA	NA
WP_003616301.1\|104889_105453_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_003616300.1\|105710_106712_-	D-2-hydroxyacid dehydrogenase	M1H502	Paramecium_bursaria_Chlorella_virus	2.2e-50	35.6
WP_003616299.1\|107001_108399_-	FAD-binding protein	NA	NA	NA	NA
WP_003616298.1\|108587_109019_+	peptide deformylase	A0A067XQZ3	Caulobacter_phage	9.1e-09	41.7
WP_002879583.1\|109583_110063_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_003614608.1\|110653_111322_+\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	5.7e-50	49.8
WP_003616294.1\|113626_114328_-	hypothetical protein	NA	NA	NA	NA
WP_003612481.1\|114566_115475_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	2.0e-05	43.3
WP_003616291.1\|115610_116741_+	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	A0A218MNE0	uncultured_virus	5.6e-66	38.9
WP_003616290.1\|116907_117846_+	ROK family glucokinase	NA	NA	NA	NA
WP_003616289.1\|117897_118821_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_003616288.1\|119543_120770_-	MFS transporter	NA	NA	NA	NA
WP_072538343.1\|121091_121247_+	fumarate reductase flavoprotein subunit	NA	NA	NA	NA
WP_003616285.1\|121390_122311_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003616283.1\|122495_122981_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_155517557.1\|123665_124361_+	hypothetical protein	NA	NA	NA	NA
WP_003612438.1\|124394_124574_+	hypothetical protein	NA	NA	NA	NA
WP_157737563.1\|124655_126061_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.6e-25	31.2
WP_050782123.1\|126192_127125_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_003612485.1\|127169_128096_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	1.0e-57	40.7
WP_003616276.1\|128257_130138_+	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	1.0e-221	64.0
WP_016395838.1\|130185_131553_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003616273.1\|132327_133086_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_003616272.1\|133174_134371_+	ATP-binding protein	NA	NA	NA	NA
WP_041812036.1\|136826_138050_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.7e-97	49.2
WP_016395838.1\|138830_140198_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_095439300.1\|140654_141917_+\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0

DBSCAN-SWA_3

160304 : 262020

unidentified_phage(19.23%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439204.1\|160304_161354_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	6.6e-53	35.2
WP_002877735.1\|162072_162438_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_081036454.1\|162572_163241_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_003616244.1\|163250_164606_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-10	29.3
WP_003616243.1\|164905_166381_+	MFS transporter	NA	NA	NA	NA
WP_003616242.1\|166444_167293_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003616241.1\|167349_168168_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003616240.1\|168225_168438_-	hypothetical protein	NA	NA	NA	NA
WP_003616238.1\|168451_169066_-	hypothetical protein	NA	NA	NA	NA
WP_095439200.1\|169592_171344_+\|transposase	transposase	NA	NA	NA	NA
WP_011544347.1\|171315_171540_+	hypothetical protein	NA	NA	NA	NA
WP_003616235.1\|171802_172702_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_003616234.1\|172718_173273_-	LemA family protein	A0A1X9IGG1	Lactococcus_phage	7.8e-13	32.0
WP_003616233.1\|173430_174588_-	cation transporter	NA	NA	NA	NA
WP_072538245.1\|175086_176136_-\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	6.6e-53	35.2
WP_095439205.1\|176689_177601_+	HNH endonuclease	NA	NA	NA	NA
WP_035182845.1\|177830_178958_+	LysM peptidoglycan-binding domain-containing protein	D2KRB9	Lactobacillus_phage	1.8e-19	45.0
WP_003616227.1\|179458_182170_+	EAL domain-containing protein	NA	NA	NA	NA
WP_003616225.1\|182242_183199_-	hypothetical protein	NA	NA	NA	NA
WP_095439301.1\|183358_184621_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_035183021.1\|186076_186265_-	hypothetical protein	NA	NA	NA	NA
WP_003616221.1\|187672_189256_-	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_003611679.1\|189644_190271_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_003616220.1\|190353_190725_+	DUF488 family protein	NA	NA	NA	NA
WP_035182842.1\|190711_191410_-	NAD-dependent protein deacylase	NA	NA	NA	NA
WP_003611605.1\|191520_192000_+	hypothetical protein	NA	NA	NA	NA
WP_003616218.1\|192051_193515_-	cardiolipin synthase	NA	NA	NA	NA
WP_003616217.1\|193516_194461_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003616215.1\|194533_195301_+	viroplasmin family protein	C1KFJ1	Lactobacillus_virus	9.2e-28	33.5
WP_003616213.1\|195388_196345_-	DUF1002 domain-containing protein	NA	NA	NA	NA
WP_086356046.1\|196514_197351_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_003616211.1\|197334_197994_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003616207.1\|199963_200797_+	hypothetical protein	NA	NA	NA	NA
WP_003616206.1\|200836_201487_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003616204.1\|201524_202832_-	CAP domain-containing protein	NA	NA	NA	NA
WP_003616202.1\|202979_204068_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_003616200.1\|204116_204752_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003616199.1\|204885_205995_+	YibE/F family protein	NA	NA	NA	NA
WP_003616198.1\|205991_206786_+	YibE/F family protein	NA	NA	NA	NA
WP_003616197.1\|206751_207618_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003616196.1\|207778_209401_+	alpha-glucosidase	NA	NA	NA	NA
WP_003616195.1\|209550_210510_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	8.8e-12	23.3
WP_003616194.1\|210629_212285_+	alpha-glucosidase	NA	NA	NA	NA
WP_016395838.1\|212367_213735_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_095439206.1\|213973_215197_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.3e-97	49.2
WP_003616193.1\|215594_216734_+	LCP family protein	NA	NA	NA	NA
WP_002879494.1\|216852_217230_+	hypothetical protein	NA	NA	NA	NA
WP_003616190.1\|217244_218789_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2H4UUX5	Bodo_saltans_virus	9.1e-43	27.8
WP_016396189.1\|218841_219597_+	threonine/serine exporter family protein	NA	NA	NA	NA
WP_003616188.1\|219599_220091_+	threonine/serine exporter family protein	NA	NA	NA	NA
WP_095439300.1\|220324_221587_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_003616186.1\|221828_221960_+	hypothetical protein	NA	NA	NA	NA
WP_003616185.1\|222015_222465_-	hypothetical protein	NA	NA	NA	NA
WP_003616183.1\|222471_223347_-	hypothetical protein	NA	NA	NA	NA
WP_003616182.1\|223884_225267_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	1.5e-52	34.2
WP_002879488.1\|225770_226286_+	hypothetical protein	NA	NA	NA	NA
WP_003616181.1\|226288_226915_+	hypothetical protein	NA	NA	NA	NA
WP_003616180.1\|226965_228504_-	O-antigen ligase family protein	NA	NA	NA	NA
WP_002879482.1\|228567_228897_-	DUF2187 family protein	NA	NA	NA	NA
WP_002879481.1\|228986_229529_+	AAA family ATPase	U5J9X2	Bacillus_phage	2.2e-12	35.4
WP_003616177.1\|229653_230139_+	C40 family peptidase	A0A2L1IW19	Streptomyces_phage	2.5e-15	40.4
WP_057727110.1\|230423_231470_+	lactate dehydrogenase	M1H502	Paramecium_bursaria_Chlorella_virus	3.3e-28	30.1
WP_035182838.1\|231550_232402_+	magnesium transporter	NA	NA	NA	NA
WP_148465392.1\|232609_233863_+	glycosyltransferase	A0A1V0S9E5	Catovirus	3.8e-07	24.2
WP_003616172.1\|233878_235015_+	beta-glucanase	NA	NA	NA	NA
WP_169787792.1\|235014_235341_+\|transposase	transposase	NA	NA	NA	NA
WP_095439198.1\|235454_236504_+\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	1.1e-52	35.2
WP_003616168.1\|236810_237284_+	C40 family peptidase	A0A2L1IW19	Streptomyces_phage	1.2e-14	42.7
WP_003616166.1\|237471_238254_+	C40 family peptidase	A0A2L1IW19	Streptomyces_phage	3.4e-14	42.7
WP_095439207.1\|239272_240031_+	C40 family peptidase	A0A0A8WF62	Clostridium_phage	5.2e-15	40.2
WP_003611201.1\|240076_240856_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.1e-07	36.9
WP_003616162.1\|240904_242188_-	GTPase HflX	NA	NA	NA	NA
WP_095439208.1\|242323_243373_-\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	1.5e-52	35.2
WP_003616161.1\|243768_244803_+	LCP family protein	NA	NA	NA	NA
WP_003616160.1\|244802_245690_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_003616159.1\|245699_246482_+	CpsD/CapB family tyrosine-protein kinase	NA	NA	NA	NA
WP_003616158.1\|246485_247262_+	hypothetical protein	NA	NA	NA	NA
WP_035161536.1\|247295_248168_+	glycosyltransferase	NA	NA	NA	NA
WP_095439198.1\|248321_249371_+\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	1.1e-52	35.2
WP_003616151.1\|250159_251239_+	glycoside hydrolase family 99-like domain-containing protein	A0A1V0SDW6	Indivirus	9.9e-28	28.8
WP_003616150.1\|251263_252406_+	glycosyltransferase	NA	NA	NA	NA
WP_003616149.1\|252416_253502_+	EpsG family protein	NA	NA	NA	NA
WP_003616148.1\|253523_253907_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	1.1e-10	33.0
WP_003616147.1\|253912_254497_+	hypothetical protein	NA	NA	NA	NA
WP_095439210.1\|254651_255749_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_011544347.1\|255680_255905_-	hypothetical protein	NA	NA	NA	NA
WP_095439200.1\|255876_257628_-\|transposase	transposase	NA	NA	NA	NA
WP_057727135.1\|257785_258025_+	hypothetical protein	NA	NA	NA	NA
WP_095439211.1\|258073_259516_+	flippase	NA	NA	NA	NA
WP_003616140.1\|259723_259906_+	hypothetical protein	NA	NA	NA	NA
WP_011544347.1\|260072_260297_-	hypothetical protein	NA	NA	NA	NA
WP_095439212.1\|260268_262020_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_4

289105 : 343765

unidentified_phage(21.43%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439214.1\|289105_289774_+\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	9.7e-50	49.8
WP_095439215.1\|289742_291449_+\|transposase	transposase	NA	NA	NA	NA
WP_095439216.1\|291698_291944_+	hypothetical protein	NA	NA	NA	NA
WP_035182815.1\|292260_293148_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_035182812.1\|293487_296742_+	SLAP domain-containing protein	NA	NA	NA	NA
WP_003616098.1\|296905_298135_+	LCP family protein	NA	NA	NA	NA
WP_003616097.1\|300030_301011_+	LCP family protein	NA	NA	NA	NA
WP_095439199.1\|301284_302652_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003616096.1\|302782_303379_+	sugar transferase	NA	NA	NA	NA
WP_003616095.1\|303395_304172_+	DUF4422 domain-containing protein	NA	NA	NA	NA
WP_003616094.1\|304192_305308_+	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	3.1e-157	71.5
WP_003616092.1\|305528_306434_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_095439217.1\|306740_307790_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	8.6e-53	35.2
WP_003616085.1\|310129_311563_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_003616084.1\|311576_312488_+	LicD family protein	A0A1V0SD50	Indivirus	3.6e-07	51.1
WP_003616083.1\|312504_312969_+	glycerol-3-phosphate cytidylyltransferase	A0A0F7LBI5	uncultured_marine_virus	8.3e-16	39.2
WP_003616082.1\|313036_314299_-	beta-carotene 15,15'-monooxygenase	NA	NA	NA	NA
WP_003616081.1\|314309_314978_-	hypothetical protein	NA	NA	NA	NA
WP_003616076.1\|316982_318644_-	hypothetical protein	NA	NA	NA	NA
WP_003616075.1\|318740_319550_-	hypothetical protein	NA	NA	NA	NA
WP_003616074.1\|319792_320242_-	VanZ family protein	NA	NA	NA	NA
WP_003616072.1\|320968_321676_+	VanZ family protein	NA	NA	NA	NA
WP_095439217.1\|321999_323049_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	8.6e-53	35.2
WP_003613114.1\|324589_324724_+	hypothetical protein	NA	NA	NA	NA
WP_035165265.1\|324743_325247_+	hypothetical protein	NA	NA	NA	NA
WP_003616066.1\|325553_326246_-	glycerophosphoryl diester phosphodiesterase	M1ICP4	Paramecium_bursaria_Chlorella_virus	4.7e-15	29.8
WP_003616065.1\|326356_327010_-	phosphoglycerate mutase family protein	A0A1X9IGJ2	Lactococcus_phage	3.2e-05	45.6
WP_003612123.1\|327024_327687_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003616061.1\|327882_330162_+	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_003616060.1\|330525_331167_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_003616059.1\|331178_331811_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.8e-28	36.3
WP_013440141.1\|331813_332644_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003616057.1\|332705_333455_-	hypothetical protein	NA	NA	NA	NA
WP_003616056.1\|333460_333904_-	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_003616055.1\|334032_334602_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_003612148.1\|334704_335619_+	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	6.4e-28	33.9
WP_002879354.1\|335671_336229_+	elongation factor P	NA	NA	NA	NA
WP_003616052.1\|336284_337082_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003616051.1\|337229_338144_-	proline-specific peptidase family protein	NA	NA	NA	NA
WP_016395838.1\|338895_340263_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_016396871.1\|340992_342588_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.0e-14	32.8
WP_157737565.1\|342564_342741_-	hypothetical protein	NA	NA	NA	NA
WP_095439217.1\|342715_343765_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	8.6e-53	35.2

DBSCAN-SWA_5

368050 : 463105

Ralstonia_virus(17.65%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003612150.1\|368050_369358_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.0e-91	49.0
WP_003616016.1\|369515_370079_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_003616015.1\|370092_370959_+	DUF3298 domain-containing protein	NA	NA	NA	NA
WP_003616013.1\|376776_377379_+	amidohydrolase family protein	NA	NA	NA	NA
WP_003616012.1\|377457_378177_-	hypothetical protein	NA	NA	NA	NA
WP_057727119.1\|378253_379123_-	DNA-binding domain-containing protein	NA	NA	NA	NA
WP_003616008.1\|379429_380431_+	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_003616007.1\|380449_381379_+	carbamate kinase	NA	NA	NA	NA
WP_095439221.1\|381720_382944_+	arginine deiminase	NA	NA	NA	NA
WP_003616000.1\|388463_389633_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_003611152.1\|389625_390675_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_003615999.1\|390667_391681_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_095439222.1\|391699_393772_+	LTA synthase family protein	W6LM83	Streptococcus_phage	3.1e-139	45.2
WP_002876914.1\|393826_394060_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_035182797.1\|394126_396496_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.1e-76	35.2
WP_003611142.1\|396518_396980_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	7.9e-43	58.6
WP_095439300.1\|397184_398447_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_003615992.1\|398972_399449_+	hypothetical protein	NA	NA	NA	NA
WP_003615990.1\|399460_400696_+	ABC transporter permease	NA	NA	NA	NA
WP_003615989.1\|400695_401376_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-23	30.9
WP_003615988.1\|401378_401546_+	hypothetical protein	NA	NA	NA	NA
WP_003615987.1\|401810_403145_+	6-phospho-alpha-glucosidase	NA	NA	NA	NA
WP_003615985.1\|405161_405944_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_003615984.1\|405943_406444_+	hypothetical protein	NA	NA	NA	NA
WP_003615983.1\|406449_406938_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_003615982.1\|407110_407605_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003615981.1\|407815_408595_+	Fe-S cluster assembly ATPase SufC	A0A285PWH2	Cedratvirus	4.5e-14	29.7
WP_003615979.1\|408604_409768_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_003615977.1\|409748_410963_+	SufS family cysteine desulfurase	Q2XUY6	environmental_halophage	1.5e-88	41.4
WP_003615975.1\|410949_411390_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_003615973.1\|411390_412818_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_003615971.1\|412903_414118_-	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_095439223.1\|419965_420625_+\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	9.2e-45	47.7
WP_003615967.1\|422618_423998_-	Na+/H+ antiporter NhaC	NA	NA	NA	NA
WP_016395838.1\|424398_425766_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003615966.1\|426404_427439_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_003615963.1\|427457_428270_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_003615961.1\|428298_429213_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_003615959.1\|429222_429591_+	DUF956 family protein	NA	NA	NA	NA
WP_003615956.1\|430214_431585_-	amino acid permease	NA	NA	NA	NA
WP_003615955.1\|431777_432620_+	C40 family peptidase	NA	NA	NA	NA
WP_003615954.1\|432812_433802_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	3.6e-53	38.7
WP_003615953.1\|433919_435062_-	DNA cytosine methyltransferase	A7XXH6	Thermus_virus	2.5e-29	29.6
WP_003615951.1\|435210_436398_+	NgoFVII family restriction endonuclease	NA	NA	NA	NA
WP_003615944.1\|438287_439457_+	NgoFVII family restriction endonuclease	NA	NA	NA	NA
WP_003615943.1\|439462_439912_+	very short patch repair endonuclease	V5UTF4	Oenococcus_phage	8.5e-34	63.0
WP_095439224.1\|441312_441588_-	hypothetical protein	V5US45	Oenococcus_phage	3.9e-21	76.6
WP_095439225.1\|441804_443172_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_035182793.1\|445018_447769_+	hypothetical protein	NA	NA	NA	NA
WP_003615939.1\|449706_450672_+	hypothetical protein	NA	NA	NA	NA
WP_003615937.1\|450673_451381_+	hypothetical protein	NA	NA	NA	NA
WP_003615935.1\|451386_452379_+	NgoFVII family restriction endonuclease	NA	NA	NA	NA
WP_095439226.1\|452413_453601_+	DNA (cytosine-5-)-methyltransferase	D2IZY5	Enterococcus_phage	3.5e-26	32.6
WP_003617894.1\|455378_455636_+	super-infection exclusion protein B	NA	NA	NA	NA
WP_157737566.1\|456899_457238_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_003615931.1\|458410_459646_-	OFA family MFS transporter	NA	NA	NA	NA
WP_003615930.1\|459932_461222_+	alpha-amylase	NA	NA	NA	NA
WP_016395838.1\|461737_463105_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1

DBSCAN-SWA_6

549972 : 600503

Planktothrix_phage(13.64%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439235.1\|549972_551022_-\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	8.6e-53	35.2
WP_003616753.1\|551590_552511_+	ABC transporter permease	NA	NA	NA	NA
WP_003616755.1\|552532_553564_+	ABC transporter permease	NA	NA	NA	NA
WP_013439040.1\|553577_554621_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-19	32.2
WP_003616760.1\|554635_555589_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.5e-21	33.3
WP_095439236.1\|555542_555803_+	DUF975 family protein	NA	NA	NA	NA
WP_003616764.1\|555934_557248_-	aminopeptidase	R4TV59	Phaeocystis_globosa_virus	3.7e-61	32.3
WP_003616771.1\|558710_559124_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_002877232.1\|559351_559813_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_003616773.1\|559894_561184_-	adenylosuccinate synthase	L7Y4J5	Megavirus	1.4e-73	38.2
WP_003616774.1\|561368_562361_+	GMP reductase	Q4ZCY7	Staphylococcus_virus	2.7e-133	68.7
WP_016395838.1\|562631_563999_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003619451.1\|565156_565516_+	hypothetical protein	E3W8I0	Leuconostoc_phage	7.8e-06	34.8
WP_003616783.1\|565585_566878_-	purine permease	Q9KX94	Enterobacteria_phage	1.4e-28	30.2
WP_003616785.1\|566907_567477_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_095439201.1\|567735_569103_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	7.1e-31	29.1
WP_002877243.1\|569347_570505_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.6e-53	41.2
WP_095439237.1\|570504_572058_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	7.8e-18	29.7
WP_003616790.1\|572382_572634_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_003616793.1\|572620_572992_+	type II toxin-antitoxin system HicB family antitoxin	A0A0K2CZV4	Paenibacillus_phage	8.9e-21	45.6
WP_095439300.1\|573274_574537_+\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_003616800.1\|577199_578810_+	ABC transporter ATP-binding protein	A0A076FI99	Aureococcus_anophage	1.1e-17	27.6
WP_035182900.1\|578844_579687_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003616804.1\|579843_581316_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	3.7e-25	24.9
WP_003616806.1\|581368_581599_-	hypothetical protein	NA	NA	NA	NA
WP_003616808.1\|581648_581864_-	hypothetical protein	NA	NA	NA	NA
WP_002876658.1\|581964_582777_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_003616812.1\|582828_583578_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-31	38.4
WP_035161049.1\|583574_584285_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_003616815.1\|584705_584960_+	hypothetical protein	NA	NA	NA	NA
WP_003616821.1\|585547_586810_-	carboxylate--amine ligase	NA	NA	NA	NA
WP_035160947.1\|586902_587868_-	Crp/Fnr family transcriptional regulator	A0A1B3AYT3	Gordonia_phage	2.8e-05	31.7
WP_003616826.1\|588013_589408_-	amino acid permease	NA	NA	NA	NA
WP_035160948.1\|589485_590418_+	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_003616830.1\|590473_590935_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_002876645.1\|591295_591742_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003616833.1\|591723_592746_+	asparaginase	NA	NA	NA	NA
WP_016395838.1\|592835_594203_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003616837.1\|595302_595779_+	large conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_003616839.1\|595858_597292_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.3e-103	45.1
WP_003616841.1\|597360_597915_-	cysteine hydrolase	G3MA16	Bacillus_virus	3.1e-33	39.1
WP_035160952.1\|598167_599025_+	hypothetical protein	NA	NA	NA	NA
WP_003616849.1\|599017_599284_-	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_003616851.1\|599380_600151_-	NUDIX hydrolase	G3MA14	Bacillus_virus	1.6e-08	25.0
WP_157737568.1\|600326_600503_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_7

722029 : 792811

Catovirus(18.75%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003617020.1\|722029_722335_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_002878083.1\|722334_723777_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_003617022.1\|723782_725213_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_003617024.1\|725248_726175_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	1.4e-14	25.9
WP_003617027.1\|726235_726949_+	DUF1211 domain-containing protein	NA	NA	NA	NA
WP_003617030.1\|726951_728307_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	5.8e-110	48.1
WP_003617032.1\|728727_729525_+	Mrr restriction system protein	NA	NA	NA	NA
WP_003617037.1\|729804_730440_+	carbonic anhydrase family protein	NA	NA	NA	NA
WP_003617044.1\|732708_733269_+	hypothetical protein	NA	NA	NA	NA
WP_003617046.1\|733417_735346_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.9e-94	34.0
WP_003617048.1\|735368_735596_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_003617050.1\|735646_735928_+	hypothetical protein	NA	NA	NA	NA
WP_003617051.1\|735952_736603_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_157737569.1\|736685_738090_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.4e-42	40.7
WP_003617053.1\|738153_738921_-	hypothetical protein	NA	NA	NA	NA
WP_003617055.1\|739036_739324_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003617057.1\|739345_739609_+	hypothetical protein	NA	NA	NA	NA
WP_003617060.1\|740922_742344_+	pyridoxal-dependent decarboxylase	NA	NA	NA	NA
WP_003617067.1\|745726_746941_+	MFS transporter	NA	NA	NA	NA
WP_016395775.1\|747072_747399_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003617072.1\|747512_747926_+	trp repressor-binding protein	NA	NA	NA	NA
WP_003617074.1\|748042_748924_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.8e-50	39.4
WP_095439199.1\|748994_750362_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_035183061.1\|752131_752803_+	DNA alkylation repair protein	NA	NA	NA	NA
WP_003617081.1\|752846_753353_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_148465398.1\|753668_755804_+	EAL domain-containing protein	NA	NA	NA	NA
WP_003617084.1\|756213_757542_+	HNH endonuclease	Q331Y3	Clostridium_botulinum_C_phage	8.6e-58	39.5
WP_003617086.1\|757634_758219_+	nodulation protein L	NA	NA	NA	NA
WP_003617088.1\|758289_758646_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_003617090.1\|758771_759257_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_003617092.1\|759465_761277_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	Q76DQ7	Chlorella_virus	6.0e-94	37.7
WP_016395838.1\|762088_763456_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003611500.1\|765158_767030_+	PTS mannitol transporter subunit IICB	NA	NA	NA	NA
WP_003617099.1\|767495_768641_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_035182921.1\|768765_771495_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_003617105.1\|771887_773510_+	ATP-binding cassette domain-containing protein	A0A1V0SKJ1	Klosneuvirus	4.3e-51	28.2
WP_003617107.1\|773569_773692_-	hypothetical protein	NA	NA	NA	NA
WP_035162331.1\|773853_774219_-	hypothetical protein	NA	NA	NA	NA
WP_095439245.1\|774461_775661_-	MFS transporter	NA	NA	NA	NA
WP_095439305.1\|775789_777052_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	5.9e-56	46.4
WP_003617113.1\|777256_777970_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_003617115.1\|778236_779022_+	glutamate racemase	NA	NA	NA	NA
WP_003617117.1\|779099_780521_+	C69 family dipeptidase	NA	NA	NA	NA
WP_003617119.1\|780534_781620_+	M42 family peptidase	NA	NA	NA	NA
WP_016395747.1\|781827_782397_+	ECF transporter S component	NA	NA	NA	NA
WP_003617123.1\|782726_783353_-	uridine kinase	A0A1V0SAA3	Catovirus	7.2e-39	42.8
WP_003617126.1\|783352_784009_-	uridine kinase	A0A1V0SAA3	Catovirus	9.9e-39	39.7
WP_003617127.1\|784551_785292_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-33	41.7
WP_003617129.1\|785313_786153_+	glutamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002878013.1\|786152_786794_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002878011.1\|786805_787474_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_003617132.1\|787515_788361_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_016395838.1\|788497_789865_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003617134.1\|790082_791594_+	HD domain-containing protein	NA	NA	NA	NA
WP_095439208.1\|791761_792811_+\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	1.5e-52	35.2

DBSCAN-SWA_8

932802 : 985770

Bacillus_phage(26.67%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439306.1\|932802_934065_+\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_095439250.1\|934064_934403_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_002880036.1\|934399_934837_+	type II secretion system protein	NA	NA	NA	NA
WP_003617365.1\|934826_935093_+	type II secretion system protein	NA	NA	NA	NA
WP_050782112.1\|935061_935679_+	hypothetical protein	NA	NA	NA	NA
WP_002880040.1\|935820_936819_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003614731.1\|936852_938040_+	acetate kinase	NA	NA	NA	NA
WP_095439300.1\|938885_940148_+\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_003617369.1\|940224_940380_+	hypothetical protein	NA	NA	NA	NA
WP_002880043.1\|940559_941285_+	response regulator transcription factor	NA	NA	NA	NA
WP_003617371.1\|941281_942847_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	9.9e-29	32.0
WP_003617373.1\|942894_945117_-	LTA synthase family protein	W6LM83	Streptococcus_phage	1.7e-146	43.2
WP_095439199.1\|945313_946681_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_050782113.1\|946835_947405_+	VanZ family protein	NA	NA	NA	NA
WP_095439201.1\|947430_948798_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	7.1e-31	29.1
WP_003617377.1\|949000_950341_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_003617386.1\|952513_953518_+	serine hydrolase	A0A1D8EXR7	Mycobacterium_phage	2.3e-10	22.2
WP_003617388.1\|953540_953792_+	hypothetical protein	NA	NA	NA	NA
WP_016396364.1\|953853_955209_-	Mur ligase family protein	NA	NA	NA	NA
WP_013439306.1\|955349_955952_+	thymidine kinase	C1KFH3	Lactobacillus_virus	2.2e-45	49.7
WP_003617391.1\|955975_957061_+	peptide chain release factor 1	NA	NA	NA	NA
WP_003617392.1\|957053_957896_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_002880061.1\|957895_958891_+	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	7.2e-49	38.0
WP_002880062.1\|958990_959620_+	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_003613585.1\|959736_960456_+	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_003617393.1\|960474_960699_+	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_003617394.1\|960752_961259_+	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_003617395.1\|961258_961801_+	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_016396362.1\|961823_963335_+	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_003617398.1\|963345_964308_+	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_016396361.1\|964327_965767_+	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_003617401.1\|965778_966219_+	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_004560494.1\|966267_966498_+	DUF1146 domain-containing protein	NA	NA	NA	NA
WP_016396360.1\|966583_967573_+	rod shape-determining protein	NA	NA	NA	NA
WP_003617406.1\|967575_967863_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	6.0e-17	45.8
WP_002880076.1\|967875_968103_+	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_003617409.1\|968127_969318_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_003617412.1\|969389_969851_-	universal stress protein	NA	NA	NA	NA
WP_003617414.1\|969908_970193_-	hypothetical protein	NA	NA	NA	NA
WP_003617415.1\|970544_971849_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	2.9e-106	51.4
WP_003617417.1\|971845_972310_-	YueI family protein	NA	NA	NA	NA
WP_003617420.1\|972434_973046_-	30S ribosomal protein S4	NA	NA	NA	NA
WP_072538245.1\|973219_974269_+\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	6.6e-53	35.2
WP_003617422.1\|974594_976313_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_003617423.1\|976398_977556_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	7.1e-40	32.4
WP_003617425.1\|977558_978776_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_003617427.1\|978775_979501_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_003617431.1\|979763_982403_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	5.4e-160	42.3
WP_003617432.1\|982407_983673_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_169845245.1\|983690_984377_+	HAD family phosphatase	NA	NA	NA	NA
WP_095439252.1\|984402_985770_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	3.2e-31	29.1

DBSCAN-SWA_9

1118700 : 1189412

Ralstonia_virus(23.08%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016395838.1\|1118700_1120068_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_072538245.1\|1120231_1121281_+\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	6.6e-53	35.2
WP_003617646.1\|1121434_1124296_+	YfhO family protein	NA	NA	NA	NA
WP_003617648.1\|1124373_1125216_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003617656.1\|1126523_1126808_-	hypothetical protein	NA	NA	NA	NA
WP_003617658.1\|1126846_1129273_+	hypothetical protein	NA	NA	NA	NA
WP_002877544.1\|1129308_1129728_+	hypothetical protein	NA	NA	NA	NA
WP_095439300.1\|1129768_1131031_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_155114311.1\|1131243_1131390_+	hypothetical protein	NA	NA	NA	NA
WP_003617664.1\|1131434_1132340_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003617666.1\|1132358_1133264_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003617670.1\|1135093_1136476_+	argininosuccinate lyase	NA	NA	NA	NA
WP_035164806.1\|1136735_1136939_+	hypothetical protein	NA	NA	NA	NA
WP_003617675.1\|1137277_1137502_-	helix-turn-helix transcriptional regulator	B8R666	Lactobacillus_phage	2.3e-11	51.4
WP_003617676.1\|1137956_1138652_+	FMN-binding protein	A0A2P0ZL82	Lactobacillus_phage	4.7e-15	33.7
WP_003617677.1\|1138710_1139103_+	FAD-binding protein	NA	NA	NA	NA
WP_003617678.1\|1139115_1139757_+	FAD-binding protein	NA	NA	NA	NA
WP_003617679.1\|1139942_1140551_+	GTP pyrophosphokinase	NA	NA	NA	NA
WP_003617686.1\|1140553_1141222_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.3e-17	28.5
WP_095439258.1\|1141224_1142484_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_003617689.1\|1142531_1144964_+	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_003617694.1\|1145121_1145856_+	type I-C CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_003617696.1\|1145852_1147727_+	type I-C CRISPR-associated protein Cas8c/Csd1	NA	NA	NA	NA
WP_095439259.1\|1147746_1148601_+	type I-C CRISPR-associated protein Cas7/Csd2	NA	NA	NA	NA
WP_003617700.1\|1149261_1150293_+	type I-C CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_035165464.1\|1150306_1150597_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_095439242.1\|1151717_1153085_-\|transposase	ISL3 family transposase	A4PE56	Ralstonia_virus	1.1e-31	29.4
WP_003617706.1\|1153317_1154418_+	thiolase family protein	NA	NA	NA	NA
WP_003617708.1\|1154419_1155646_+	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
WP_003613854.1\|1155649_1156813_+	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_003617712.1\|1156976_1158335_+	threonine/serine exporter family protein	NA	NA	NA	NA
WP_035164818.1\|1158391_1158898_-\|tRNA	aminoacyl-tRNA deacylase	NA	NA	NA	NA
WP_003617719.1\|1158960_1159905_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_003617724.1\|1160045_1162307_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1X9SH80	Bradyrhizobium_phage	5.7e-09	34.9
WP_003613864.1\|1162335_1162773_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_003617729.1\|1163058_1164345_+\|tRNA	histidine--tRNA ligase	A0A1V0S921	Catovirus	2.9e-26	25.7
WP_003617731.1\|1164360_1166205_+\|tRNA	aspartate--tRNA ligase	A0A1V0SFI4	Hokovirus	3.1e-05	33.7
WP_095439260.1\|1166913_1168689_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_003617737.1\|1168764_1169838_+	AI-2E family transporter	NA	NA	NA	NA
WP_003611786.1\|1171590_1172550_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_016395838.1\|1172711_1174079_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_002877474.1\|1174138_1174384_+	acyl carrier protein	NA	NA	NA	NA
WP_003617742.1\|1174396_1175341_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_003617745.1\|1175324_1176047_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	9.9e-16	31.7
WP_003617746.1\|1176056_1177277_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_035183091.1\|1177279_1177750_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_002877460.1\|1177751_1178195_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_003617750.1\|1178187_1179570_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_003611769.1\|1179556_1180405_+	hypothetical protein	NA	NA	NA	NA
WP_003617752.1\|1180397_1181165_+	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_035183093.1\|1181174_1181939_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_003617756.1\|1181948_1182614_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_003611793.1\|1182862_1183483_-	DUF3862 domain-containing protein	NA	NA	NA	NA
WP_035182949.1\|1183640_1183862_+	hypothetical protein	NA	NA	NA	NA
WP_003617766.1\|1184298_1185069_+	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_035182951.1\|1185191_1187894_-	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_095439261.1\|1188362_1189412_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.1e-52	35.2

DBSCAN-SWA_10

1196013 : 1240838

Bacillus_phage(23.08%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439300.1\|1196013_1197276_+\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_003614946.1\|1197338_1198931_-	asparagine synthase B	L7RC73	Acanthamoeba_polyphaga_moumouvirus	1.4e-99	39.4
WP_003614947.1\|1201144_1202764_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003614948.1\|1202854_1203097_+	hypothetical protein	NA	NA	NA	NA
WP_003614953.1\|1203653_1203803_+	hypothetical protein	NA	NA	NA	NA
WP_003614955.1\|1203882_1204647_-	hypothetical protein	NA	NA	NA	NA
WP_016395838.1\|1204759_1206127_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003614957.1\|1208327_1209212_+	phosphate ABC transporter substrate-binding protein	A0A1D7SQC1	Cyanophage	3.2e-08	30.2
WP_003614665.1\|1209231_1210140_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_003614664.1\|1210142_1211018_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_035182682.1\|1211020_1211776_+	phosphate ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.4e-15	28.9
WP_003614960.1\|1211794_1212433_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_002878532.1\|1212518_1213196_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.2e-32	38.2
WP_003614964.1\|1213195_1214854_+	GHKL domain-containing protein	W8CYF6	Bacillus_phage	2.3e-31	35.1
WP_095439262.1\|1215371_1216739_-\|transposase	ISL3 family transposase	A4PE56	Ralstonia_virus	1.1e-31	29.4
WP_003614970.1\|1218370_1219027_-	NUDIX hydrolase	NA	NA	NA	NA
WP_155114309.1\|1219103_1219247_+	hypothetical protein	NA	NA	NA	NA
WP_095439243.1\|1219336_1219879_+	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	2.2e-07	26.7
WP_095439261.1\|1220072_1221122_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.1e-52	35.2
WP_003614974.1\|1222092_1222644_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_035182684.1\|1223004_1224561_-	YfcC family protein	NA	NA	NA	NA
WP_003614977.1\|1224807_1225575_-	ABC transporter ATP-binding protein	F2Y1V6	Organic_Lake_phycodnavirus	3.3e-09	28.2
WP_003614648.1\|1226361_1227138_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_003614981.1\|1227134_1227749_-	membrane protein	NA	NA	NA	NA
WP_003614982.1\|1228138_1229248_+	EAL domain-containing protein	NA	NA	NA	NA
WP_003614984.1\|1229535_1230564_+	GGDEF domain-containing protein	G3MA91	Bacillus_virus	2.6e-09	28.0
WP_003614986.1\|1230570_1231152_+	hypothetical protein	NA	NA	NA	NA
WP_003614987.1\|1231251_1232073_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_035161335.1\|1233062_1233383_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_051975781.1\|1233468_1234026_+\|transposase	transposase	NA	NA	NA	NA
WP_095439263.1\|1234065_1234848_+\|transposase	transposase	NA	NA	NA	NA
WP_003614991.1\|1235461_1235812_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_003614992.1\|1235808_1236882_+	GTP cyclohydrolase I FolE	A0A0P0HSD2	Acinetobacter_phage	8.0e-38	42.3
WP_003614993.1\|1236865_1238203_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_003614994.1\|1238192_1239284_+	dihydropteroate synthase	NA	NA	NA	NA
WP_003614996.1\|1239295_1239832_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_095439264.1\|1240253_1240838_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_11

1268019 : 1332431

Bacillus_phage(15.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439266.1\|1268019_1269318_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.6e-53	28.9
WP_002878410.1\|1269408_1270056_+	DnaD domain protein	A0A0N7AE27	Bacillus_phage	1.0e-08	38.4
WP_002878412.1\|1270077_1270707_+	endonuclease III	NA	NA	NA	NA
WP_003615040.1\|1270741_1271545_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_120490347.1\|1271579_1272065_-	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_003615044.1\|1272058_1272487_-	hypothetical protein	NA	NA	NA	NA
WP_003615046.1\|1272647_1273649_-	D-2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.2e-37	34.2
WP_016395838.1\|1273738_1275106_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003615050.1\|1277465_1279778_-	transglycosylase domain-containing protein	NA	NA	NA	NA
WP_003615052.1\|1279764_1280397_-	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	3.4e-20	33.1
WP_013439504.1\|1280557_1281118_+	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_003615059.1\|1281193_1281658_+	cell division regulator GpsB	NA	NA	NA	NA
WP_003615060.1\|1282175_1283300_+	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_003615062.1\|1283309_1284542_+	metallophosphoesterase	NA	NA	NA	NA
WP_095439267.1\|1284696_1284888_+	hypothetical protein	NA	NA	NA	NA
WP_095439242.1\|1284963_1286331_+\|transposase	ISL3 family transposase	A4PE56	Ralstonia_virus	1.1e-31	29.4
WP_035182686.1\|1286561_1288241_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_002876847.1\|1288252_1288705_+	signal peptidase II	NA	NA	NA	NA
WP_003615065.1\|1288706_1289621_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.5e-08	27.9
WP_002876844.1\|1289622_1290678_+	carbamoyl phosphate synthase small subunit	NA	NA	NA	NA
WP_003615066.1\|1290677_1293869_+	carbamoyl phosphate synthase large subunit	NA	NA	NA	NA
WP_003615067.1\|1293962_1294244_+	ACT domain-containing protein	NA	NA	NA	NA
WP_002876840.1\|1294243_1295587_+	PFL family protein	NA	NA	NA	NA
WP_003615068.1\|1297169_1298861_-	fibronectin/fibrinogen-binding protein	A0A1J0F9J4	Only_Syngen_Nebraska_virus	1.9e-09	45.2
WP_003615069.1\|1299013_1299475_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	2.4e-39	57.4
WP_035182688.1\|1299541_1300954_+\|transposase	transposase	A0A2I7RKG5	Vibrio_phage	1.4e-10	34.0
WP_003615074.1\|1301866_1302409_-	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_095439268.1\|1302566_1303448_+	DegV family protein	NA	NA	NA	NA
WP_003615077.1\|1303503_1304577_+	hypothetical protein	NA	NA	NA	NA
WP_003615080.1\|1304642_1305554_-	EamA family transporter	NA	NA	NA	NA
WP_003615085.1\|1305754_1306930_-	3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	1.0e-102	47.6
WP_035182690.1\|1306948_1308031_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.9e-79	44.5
WP_003615090.1\|1308374_1308998_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_003615092.1\|1309056_1309398_-	ABC transporter permease	NA	NA	NA	NA
WP_003615094.1\|1309581_1310100_-	nitroreductase family protein	A0A1V0E011	Clostridioides_phage	8.4e-09	30.4
WP_035182962.1\|1310504_1311515_+	aspartate carbamoyltransferase catalytic subunit	A0A1J0F9B8	Only_Syngen_Nebraska_virus	2.0e-22	29.8
WP_003615098.1\|1311514_1312744_+	dihydroorotase	NA	NA	NA	NA
WP_016395838.1\|1312888_1314256_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003615099.1\|1314328_1315405_-	tyrosine recombinase XerS	NA	NA	NA	NA
WP_003615100.1\|1315627_1316776_+	glycerate kinase	W6LM47	Streptococcus_phage	1.7e-41	35.5
WP_003615103.1\|1318105_1318684_+	sel1 repeat family protein	NA	NA	NA	NA
WP_002878430.1\|1319662_1319833_+	hypothetical protein	NA	NA	NA	NA
WP_003615108.1\|1319967_1320435_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_148465385.1\|1320431_1321010_+	hypothetical protein	NA	NA	NA	NA
WP_035184411.1\|1321366_1321627_+	hypothetical protein	NA	NA	NA	NA
WP_003615115.1\|1321814_1322849_+	zinc-dependent alcohol dehydrogenase family protein	A0A0K0KVL7	Prochlorococcus_phage	1.7e-08	26.3
WP_003615119.1\|1322879_1323200_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_035182692.1\|1324847_1325054_+	FAD-binding protein	NA	NA	NA	NA
WP_035182693.1\|1325134_1325854_+	HAD family hydrolase	M1H9H9	Acanthocystis_turfacea_Chlorella_virus	1.9e-06	24.6
WP_035182695.1\|1325855_1326122_+	N-acetyltransferase	NA	NA	NA	NA
WP_095439300.1\|1326182_1327445_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.7e-55	46.0
WP_003615130.1\|1327684_1330228_+	YfhO family protein	NA	NA	NA	NA
WP_080553950.1\|1330355_1330853_-	nitronate monooxygenase	NA	NA	NA	NA
WP_057727132.1\|1330800_1331223_-	hypothetical protein	NA	NA	NA	NA
WP_072538245.1\|1331381_1332431_+\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	6.6e-53	35.2

DBSCAN-SWA_12

1345489 : 1565738

178

Streptococcus_phage(16.39%)

protease,transposase,integrase,tRNA

attL 1331381:1331440|attR 1552635:1552674

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1331381:1331440	attL	NA	NA	NA	NA
WP_095439269.1\|1345489_1346539_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	7.3e-52	34.9
1331381:1331440	attL	NA	NA	NA	NA
WP_080553952.1\|1346810_1347200_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_003615157.1\|1348795_1349533_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003615159.1\|1350177_1350819_+\|integrase	tyrosine-type recombinase/integrase	A3F636	Streptococcus_phage	2.3e-24	34.9
WP_003615160.1\|1351010_1351481_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003615161.1\|1351785_1352700_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.3e-25	34.8
WP_057727096.1\|1352696_1353557_+	ABC transporter permease	NA	NA	NA	NA
WP_035182708.1\|1353773_1354238_+	hypothetical protein	NA	NA	NA	NA
WP_003615169.1\|1354857_1355256_+	arsenate reductase ArsC	A0A2H4PQT9	Staphylococcus_phage	2.0e-10	35.1
WP_003615172.1\|1355469_1355796_+	hypothetical protein	NA	NA	NA	NA
WP_095439270.1\|1355957_1356710_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.8e-32	39.1
WP_003615175.1\|1356732_1358607_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_003615177.1\|1359154_1359700_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_003615178.1\|1359692_1360613_+	FAD-binding protein	NA	NA	NA	NA
WP_165380480.1\|1361509_1361686_-	hypothetical protein	NA	NA	NA	NA
WP_002880312.1\|1361976_1362183_+	hypothetical protein	NA	NA	NA	NA
WP_003615189.1\|1362878_1363436_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003615191.1\|1363661_1364198_-	SLAP domain-containing protein	NA	NA	NA	NA
WP_003614261.1\|1364229_1364817_-	peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	9.1e-28	43.4
WP_003615193.1\|1364951_1366133_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_003615195.1\|1366169_1366949_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_003615198.1\|1366951_1367881_-	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_003615199.1\|1367904_1369059_-	N-acetyldiaminopimelate deacetylase	NA	NA	NA	NA
WP_003615201.1\|1369119_1369833_-	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
WP_003615203.1\|1370345_1371719_+	aspartate kinase	NA	NA	NA	NA
WP_003615205.1\|1371720_1372707_+	diaminopimelate epimerase	NA	NA	NA	NA
WP_016396593.1\|1372753_1374022_-	hypothetical protein	NA	NA	NA	NA
WP_003615207.1\|1374030_1374381_-	hypothetical protein	NA	NA	NA	NA
WP_035182710.1\|1374743_1376075_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_003615211.1\|1377510_1378083_-	GNAT family N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	4.3e-30	40.0
WP_003615213.1\|1380097_1380616_-	Fic family protein	NA	NA	NA	NA
WP_013439619.1\|1380885_1381077_-	hypothetical protein	NA	NA	NA	NA
WP_003615220.1\|1381126_1381975_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_003615223.1\|1382019_1383444_-	RsmF rRNA methyltransferase first C-terminal domain-containing protein	NA	NA	NA	NA
WP_003615224.1\|1383436_1384411_-	hypothetical protein	NA	NA	NA	NA
WP_035161197.1\|1384410_1385151_-	hypothetical protein	NA	NA	NA	NA
WP_002880372.1\|1385260_1385458_-	hypothetical protein	NA	NA	NA	NA
WP_003615228.1\|1385605_1386217_-	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_003615229.1\|1386295_1387048_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003614258.1\|1387120_1388032_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_035161202.1\|1388190_1389621_-	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_003615231.1\|1389721_1391242_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_003615234.1\|1392490_1392949_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_003615236.1\|1393031_1393451_+	3-beta hydroxysteroid dehydrogenase	NA	NA	NA	NA
WP_095439206.1\|1395174_1396398_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.3e-97	49.2
WP_035164940.1\|1398296_1399469_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_035182712.1\|1399771_1405546_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	1.2e-10	31.1
WP_035161211.1\|1405999_1406503_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003615252.1\|1406583_1407084_-	hypothetical protein	NA	NA	NA	NA
WP_003615254.1\|1407517_1408132_+	DedA family protein	NA	NA	NA	NA
WP_003615255.1\|1408499_1409516_+	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	1.6e-59	38.8
WP_095439271.1\|1409591_1410890_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	4.8e-53	28.4
WP_003615257.1\|1410955_1411963_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_003615258.1\|1412005_1415029_-	DUF4981 domain-containing protein	L0N6M2	Herpes_simplex_virus	6.2e-136	32.5
WP_035182717.1\|1415032_1416916_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_095439309.1\|1417073_1418336_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	7.2e-54	44.9
WP_003615260.1\|1418555_1419146_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_003615263.1\|1419746_1420583_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_003615265.1\|1420626_1421193_+	signal peptidase I	NA	NA	NA	NA
WP_072538245.1\|1421256_1422306_-\|transposase	IS30-like element ISL7 family transposase	H7BUM7	unidentified_phage	6.6e-53	35.2
WP_002878604.1\|1422514_1422706_+	hypothetical protein	NA	NA	NA	NA
WP_003615268.1\|1423092_1424331_-	peptidase T	NA	NA	NA	NA
1422248:1423351	attR	NA	NA	NA	NA
WP_003615270.1\|1424374_1425172_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
1422248:1423351	attR	NA	NA	NA	NA
WP_003615272.1\|1425164_1425857_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003615274.1\|1426128_1427427_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	C1KFS0	Lactobacillus_virus	1.1e-73	39.2
WP_003615275.1\|1427793_1428234_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_003615277.1\|1428233_1429040_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_011544347.1\|1430356_1430581_-	hypothetical protein	NA	NA	NA	NA
WP_003615282.1\|1431218_1431551_-	hypothetical protein	NA	NA	NA	NA
WP_095439310.1\|1431715_1434802_-	DEAD/DEAH box helicase family protein	A0A2K5B2C2	Erysipelothrix_phage	2.9e-141	34.9
WP_035182971.1\|1434812_1436681_-	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	7.5e-116	38.9
WP_003615288.1\|1436688_1437312_-	DUF4391 domain-containing protein	NA	NA	NA	NA
WP_003615289.1\|1437312_1440549_-	helicase	A0A2K5B2B9	Erysipelothrix_phage	5.3e-234	43.8
WP_003615290.1\|1440883_1442977_-	DUF262 domain-containing protein	NA	NA	NA	NA
WP_003615291.1\|1443251_1443476_-	hypothetical protein	NA	NA	NA	NA
WP_003615293.1\|1443698_1444160_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_035182722.1\|1444180_1445017_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003615301.1\|1447192_1448104_+	alpha/beta hydrolase	L7RDF8	Acanthamoeba_polyphaga_moumouvirus	2.4e-14	25.2
WP_003615302.1\|1448155_1448875_-	diguanylate cyclase	NA	NA	NA	NA
WP_003613025.1\|1449001_1449328_-	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_003615304.1\|1449473_1450832_-	PTS cellobiose transporter subunit IIC	NA	NA	NA	NA
WP_095439272.1\|1451056_1452280_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.5e-96	48.2
WP_003615307.1\|1452542_1453076_-	hypothetical protein	NA	NA	NA	NA
WP_003615309.1\|1453097_1453496_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_003615311.1\|1453579_1453900_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_003615313.1\|1454375_1455821_+	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	3.6e-33	26.3
WP_095439273.1\|1456612_1459306_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.7e-55	46.0
WP_070489256.1\|1459516_1459855_-	LysR family transcriptional regulator substrate-binding protein	NA	NA	NA	NA
WP_003617847.1\|1459931_1460177_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_035183202.1\|1460183_1460306_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_095439274.1\|1460706_1462413_-\|transposase	transposase	NA	NA	NA	NA
WP_003614608.1\|1462381_1463050_-\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	5.7e-50	49.8
WP_003615315.1\|1463227_1464364_-	sigma-70 family RNA polymerase sigma factor	A0A2I7SAT0	Vibrio_phage	6.1e-36	33.8
WP_003615316.1\|1464399_1465521_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	2.9e-38	37.0
WP_003615317.1\|1465562_1466681_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.2e-36	34.8
WP_003615318.1\|1466652_1468491_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	5.4e-58	35.9
WP_003615319.1\|1468522_1470589_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003615321.1\|1470581_1471493_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_003615323.1\|1471758_1472508_-	DNA repair protein RecO	NA	NA	NA	NA
WP_003612996.1\|1472507_1473413_-	GTPase Era	NA	NA	NA	NA
WP_002880164.1\|1473396_1473816_-	cytidine deaminase	NA	NA	NA	NA
WP_003615327.1\|1473817_1474342_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_035161276.1\|1474341_1475289_-	PhoH family protein	H6X2N1	Pseudomonas_phage	8.9e-49	48.4
WP_002880182.1\|1475442_1475619_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_003615330.1\|1475787_1476645_+	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_003615332.1\|1476705_1476978_-	hypothetical protein	NA	NA	NA	NA
WP_003615333.1\|1477043_1477928_-	YitT family protein	M1Q1P6	Streptococcus_phage	2.6e-18	25.6
WP_003615335.1\|1478134_1478767_-\|transposase	transposase	A0A218MNE7	uncultured_virus	1.1e-13	32.1
WP_003615339.1\|1479362_1480547_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_003613129.1\|1480727_1482038_-	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_003615341.1\|1482396_1483131_-	hypothetical protein	NA	NA	NA	NA
WP_050782110.1\|1483272_1483557_-	hypothetical protein	NA	NA	NA	NA
WP_095439276.1\|1484166_1485864_-\|transposase	transposase	NA	NA	NA	NA
WP_003614608.1\|1485832_1486501_-\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	5.7e-50	49.8
WP_155517555.1\|1486605_1486863_-	hypothetical protein	NA	NA	NA	NA
WP_080553953.1\|1486862_1487108_-	hypothetical protein	NA	NA	NA	NA
WP_003613145.1\|1487430_1488327_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003615348.1\|1488412_1489807_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IB03	Erwinia_phage	6.5e-32	26.0
WP_003613136.1\|1489809_1490343_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003613135.1\|1490451_1491339_-	tyrosine recombinase XerC	S5W9T9	Leptospira_phage	6.4e-25	30.5
WP_003615349.1\|1491338_1492658_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_003615350.1\|1492789_1494964_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	1.0e-92	34.9
WP_003615351.1\|1495090_1495930_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	5.3e-29	36.9
WP_003615352.1\|1496020_1496791_-	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	3.3e-25	37.2
WP_003615353.1\|1496780_1497638_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003613715.1\|1497712_1497943_-	YozE family protein	NA	NA	NA	NA
WP_002880203.1\|1497946_1498792_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.0e-19	45.0
WP_003615360.1\|1498927_1499608_+	hemolysin III family protein	NA	NA	NA	NA
WP_095439277.1\|1499720_1500755_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	5.5e-52	34.4
WP_035161293.1\|1500851_1502042_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	2.4e-43	47.8
WP_095439201.1\|1502104_1503472_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	7.1e-31	29.1
WP_095439220.1\|1503573_1504941_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.2
WP_003615364.1\|1506757_1507657_+	YitT family protein	M1Q1P6	Streptococcus_phage	1.3e-52	40.5
WP_002880208.1\|1507691_1507937_-	hypothetical protein	NA	NA	NA	NA
WP_003615365.1\|1508010_1508307_-	EAL domain-containing protein	NA	NA	NA	NA
WP_003615366.1\|1508405_1508597_-	hypothetical protein	NA	NA	NA	NA
WP_003615368.1\|1509073_1510846_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.2e-50	26.6
WP_003615372.1\|1512973_1513876_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	5.2e-06	25.6
WP_035182728.1\|1513946_1514744_-	hypothetical protein	NA	NA	NA	NA
WP_003615376.1\|1515016_1515604_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_003615379.1\|1515699_1516536_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	5.6e-47	39.7
WP_002879863.1\|1516843_1518121_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	9.3e-110	51.4
WP_003615383.1\|1518377_1518986_-	DUF4230 domain-containing protein	NA	NA	NA	NA
WP_002879870.1\|1519494_1520235_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-30	38.8
WP_003615385.1\|1520255_1521758_+	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_003615387.1\|1521805_1522660_-	LysR family transcriptional regulator	A0A2H4J8I9	uncultured_Caudovirales_phage	9.3e-05	32.5
WP_003615389.1\|1522837_1525096_+	HAD-IC family P-type ATPase	M1HBF8	Paramecium_bursaria_Chlorella_virus	2.1e-40	27.5
WP_035182731.1\|1525373_1526507_-	AI-2E family transporter	NA	NA	NA	NA
WP_003615395.1\|1526623_1527649_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
WP_003615397.1\|1527850_1528738_-	cation transporter	NA	NA	NA	NA
WP_003615398.1\|1528849_1529152_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_035161317.1\|1529231_1529759_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	6.5e-25	41.8
WP_003615400.1\|1529748_1532025_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.8e-71	32.4
WP_003615401.1\|1532021_1532723_-	class A sortase	NA	NA	NA	NA
WP_003615403.1\|1532703_1534542_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	1.5e-20	25.5
WP_003615404.1\|1534663_1535803_-	molecular chaperone DnaJ	A0A0P0YNN4	Yellowstone_lake_phycodnavirus	3.1e-16	25.9
WP_003615406.1\|1535885_1537730_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	6.0e-142	49.3
WP_003615408.1\|1537789_1538389_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_035182733.1\|1538423_1539473_-	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_003615411.1\|1539608_1540550_-	riboflavin biosynthesis protein RibF	A0A1V0SD03	Indivirus	9.3e-06	26.9
WP_080553976.1\|1540663_1541257_-\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	7.8e-35	39.6
WP_052109142.1\|1542764_1543181_-	Arm DNA-binding domain-containing protein	Q938N9	Temperate_phage	6.1e-10	33.6
WP_095439278.1\|1544049_1544844_+\|transposase	transposase	NA	NA	NA	NA
WP_003615418.1\|1546141_1547053_+	cysteine synthase family protein	A0A1W6JIM2	Lactococcus_phage	6.3e-60	41.8
WP_003615419.1\|1547074_1548259_+	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_003615420.1\|1548224_1548782_+	serine acetyltransferase	NA	NA	NA	NA
WP_035182982.1\|1549088_1549274_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_095439225.1\|1549299_1550667_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_095439279.1\|1550905_1552129_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.9e-96	49.0
WP_095439280.1\|1552434_1552617_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_003615423.1\|1553511_1554408_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_002876717.1\|1554458_1554821_-	ribosome-binding factor A	NA	NA	NA	NA
WP_003615426.1\|1554833_1557311_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	2.3e-19	23.9
WP_002876720.1\|1557315_1557600_-	ribosomal L7Ae/L30e/S12e/Gadd45 family protein	NA	NA	NA	NA
WP_002876722.1\|1557626_1557926_-	YlxR family protein	NA	NA	NA	NA
WP_002876724.1\|1557935_1559087_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_002876725.1\|1559106_1559583_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_003615435.1\|1564040_1565738_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA

DBSCAN-SWA_13

1610681 : 1681426

Ralstonia_virus(15.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016395838.1\|1610681_1612049_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_016395838.1\|1612194_1613562_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003615490.1\|1613861_1614104_-	acyl carrier protein	E3SSM9	Prochlorococcus_phage	5.6e-08	55.2
WP_003615492.1\|1614165_1615158_-	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_003615494.1\|1615183_1617223_-	ATP-dependent DNA helicase RecG	NA	NA	NA	NA
WP_003615496.1\|1617222_1618887_-	DAK2 domain-containing protein	NA	NA	NA	NA
WP_002879711.1\|1618906_1619269_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_003615500.1\|1619444_1619630_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_035182735.1\|1619730_1621302_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-16	22.8
WP_003615503.1\|1621466_1622177_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_003618477.1\|1622173_1622416_-	hypothetical protein	NA	NA	NA	NA
WP_003615505.1\|1622647_1622785_-	hypothetical protein	NA	NA	NA	NA
WP_003615506.1\|1622980_1623664_-	thiamine diphosphokinase	NA	NA	NA	NA
WP_003615507.1\|1623693_1624587_-	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_080553956.1\|1624587_1626612_-	Stk1 family PASTA domain-containing Ser/Thr kinase	A0A1V0SD90	Indivirus	4.9e-20	26.3
WP_003615509.1\|1626583_1627339_-	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_003615510.1\|1627344_1628661_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_003611980.1\|1628650_1629598_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	4.8e-10	32.1
WP_003615511.1\|1629610_1631992_-	primosomal protein N'	NA	NA	NA	NA
WP_002879690.1\|1632054_1632276_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_003615512.1\|1632277_1632892_-	guanylate kinase	A0A223FN12	Murmansk_poxvirus	2.1e-19	29.2
WP_003615513.1\|1633065_1633371_+	hypothetical protein	NA	NA	NA	NA
WP_003615514.1\|1633487_1633820_-	peptide ABC transporter	NA	NA	NA	NA
WP_050782116.1\|1633859_1634216_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003615517.1\|1634425_1636114_-	DNA repair protein RecN	NA	NA	NA	NA
WP_003615519.1\|1636135_1636951_-	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_035182738.1\|1636950_1637814_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_003615522.1\|1637818_1638058_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_003615524.1\|1638050_1639421_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	2.1e-30	32.0
WP_003615525.1\|1639407_1640259_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	7.2e-42	44.7
WP_002879679.1\|1640317_1640716_-	transcription antitermination factor NusB	NA	NA	NA	NA
WP_002879678.1\|1640715_1641150_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_003615527.1\|1641169_1641736_-	elongation factor P	NA	NA	NA	NA
WP_016396438.1\|1641805_1642912_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_035162038.1\|1643056_1643350_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_003615531.1\|1643371_1643683_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_003615533.1\|1643923_1644280_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-16	41.8
WP_095439282.1\|1645150_1645567_-	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_095439311.1\|1645763_1647026_+\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	4.2e-54	44.2
WP_003615539.1\|1647080_1648346_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_035162042.1\|1650484_1651528_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	6.3e-64	41.3
WP_003615543.1\|1651530_1653009_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-51	32.4
WP_003615544.1\|1652984_1655207_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	6.5e-143	40.2
WP_003615545.1\|1655206_1655881_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003615547.1\|1655880_1656129_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003615550.1\|1656133_1656856_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	1.3e-36	36.8
WP_003615552.1\|1657179_1658475_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.4e-20	32.6
WP_035162044.1\|1658518_1659643_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_003615555.1\|1659632_1660100_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-18	42.2
WP_148465388.1\|1660539_1660722_-	hypothetical protein	NA	NA	NA	NA
WP_035165062.1\|1661229_1661625_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_035165064.1\|1663080_1663323_-	hypothetical protein	NA	NA	NA	NA
WP_003615571.1\|1667984_1670363_+	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
WP_035174951.1\|1671960_1672743_+	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_003615579.1\|1672785_1673709_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	8.8e-110	65.3
WP_095439272.1\|1674347_1675571_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.5e-96	48.2
WP_095439283.1\|1675693_1676947_-\|transposase	transposase	NA	NA	NA	NA
WP_003615583.1\|1677144_1678137_-	adenosine deaminase	NA	NA	NA	NA
WP_095439201.1\|1680058_1681426_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	7.1e-31	29.1

DBSCAN-SWA_14

1690957 : 1743564

Bacillus_phage(25.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003615601.1\|1690957_1691875_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003614167.1\|1691955_1692357_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_003614169.1\|1692419_1692647_-	YqgQ family protein	NA	NA	NA	NA
WP_003614162.1\|1692646_1693318_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_003615603.1\|1693310_1693883_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_002879260.1\|1693936_1694086_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_035182742.1\|1694172_1696287_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_003615605.1\|1696372_1698955_+	YfhO family protein	NA	NA	NA	NA
WP_003615606.1\|1700663_1701152_-	transcription elongation factor GreA	NA	NA	NA	NA
WP_003615607.1\|1701222_1703634_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003615610.1\|1703633_1704683_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.1e-31	34.9
WP_003615612.1\|1704962_1705313_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002879252.1\|1705394_1706159_-	RNA methyltransferase	NA	NA	NA	NA
WP_095439284.1\|1706349_1707399_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	6.6e-53	35.2
WP_003615614.1\|1707475_1707748_+	acylphosphatase	NA	NA	NA	NA
WP_003615616.1\|1707781_1708744_+	membrane protein insertase YidC	NA	NA	NA	NA
WP_003615617.1\|1708832_1710425_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_002879246.1\|1710417_1711131_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.9e-27	31.1
WP_003614912.1\|1711310_1711889_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_003615619.1\|1711888_1713043_-	nucleotidyltransferase	NA	NA	NA	NA
WP_002879243.1\|1713046_1713394_-	ribosome silencing factor	NA	NA	NA	NA
WP_003615621.1\|1713435_1714029_-	HD domain-containing protein	NA	NA	NA	NA
WP_003615623.1\|1714021_1714660_-	nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
WP_035182745.1\|1714670_1715780_-	ribosome biogenesis GTPase YqeH	NA	NA	NA	NA
WP_002879237.1\|1715888_1716245_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_002879235.1\|1716289_1716490_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_002879234.1\|1716510_1717032_-	translation initiation factor IF-3	A0A2I7S9Q1	Vibrio_phage	6.4e-17	39.7
WP_003615627.1\|1717574_1718804_+	ATP-binding protein	NA	NA	NA	NA
WP_003615631.1\|1719987_1721919_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	2.9e-94	32.8
WP_003615632.1\|1722219_1723143_-	primosomal protein DnaI	S5MU12	Brevibacillus_phage	3.9e-25	32.5
WP_003615633.1\|1723153_1724488_-	DnaD domain protein	NA	NA	NA	NA
WP_002879222.1\|1724491_1724959_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_003615637.1\|1724972_1725557_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_003615639.1\|1725565_1726387_-	DNA-formamidopyrimidine glycosylase	A0A127AWE5	Bacillus_phage	5.8e-20	29.5
WP_035182751.1\|1726397_1729061_-	DNA polymerase I	F8WQ35	Bacillus_phage	2.9e-60	29.7
WP_041812036.1\|1729695_1730919_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.7e-97	49.2
WP_095439220.1\|1732864_1734232_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.2
WP_095439220.1\|1736035_1737403_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.2
WP_003617920.1\|1738743_1740063_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_095439285.1\|1740340_1741564_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	7.9e-98	49.0
WP_003615644.1\|1741838_1742486_-\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_002879808.1\|1742508_1742829_-	thioredoxin family protein	NA	NA	NA	NA
WP_002879806.1\|1742907_1743564_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA

DBSCAN-SWA_15

1847543 : 1905316

Ralstonia_virus(20.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016395838.1\|1847543_1848911_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003617929.1\|1849047_1850166_-	serine hydrolase	NA	NA	NA	NA
WP_003615771.1\|1851865_1852528_-	ABC transporter permease	NA	NA	NA	NA
WP_016396754.1\|1852527_1853457_-	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003615773.1\|1853468_1854098_-	ABC transporter permease	NA	NA	NA	NA
WP_095439289.1\|1854100_1855348_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.8e-25	34.4
WP_095439290.1\|1855463_1856666_-\|transposase	transposase	NA	NA	NA	NA
WP_002876514.1\|1857230_1857503_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	1.1e-25	70.0
WP_095439292.1\|1858286_1859336_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	3.3e-52	35.2
WP_002876509.1\|1859531_1859897_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_002876508.1\|1859949_1860459_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_003615780.1\|1860719_1861121_+	hypothetical protein	NA	NA	NA	NA
WP_003615782.1\|1861345_1862596_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	2.9e-39	31.9
WP_003615784.1\|1862691_1863696_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_003615785.1\|1863858_1864554_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002876501.1\|1864637_1865063_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_002876498.1\|1865188_1865743_-	transcription termination/antitermination protein NusG	NA	NA	NA	NA
WP_003615789.1\|1865834_1866005_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002876495.1\|1866011_1866161_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_003615790.1\|1866336_1868088_+	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_002876482.1\|1869109_1869325_-	hypothetical protein	NA	NA	NA	NA
WP_016396767.1\|1869392_1869962_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_003615793.1\|1870073_1870823_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_002876476.1\|1870809_1871253_-	ribonuclease iii family protein	NA	NA	NA	NA
WP_003615794.1\|1871245_1872670_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	2.1e-46	30.1
WP_035182765.1\|1872812_1873379_+	NUDIX hydrolase	NA	NA	NA	NA
WP_095439199.1\|1874075_1875443_+\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_003615806.1\|1876209_1877085_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	9.5e-13	29.1
WP_035182766.1\|1878314_1879817_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_003615810.1\|1879961_1880798_-	hypothetical protein	NA	NA	NA	NA
WP_035182767.1\|1880797_1881496_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.9e-14	27.1
WP_002876367.1\|1881497_1881866_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003615812.1\|1882239_1883859_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003615813.1\|1883990_1884515_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003615814.1\|1884555_1885776_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_095439272.1\|1887486_1888710_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.5e-96	48.2
WP_003615823.1\|1889712_1890915_-	MFS transporter	NA	NA	NA	NA
WP_003615825.1\|1891209_1892331_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_003616752.1\|1893738_1895385_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_095439293.1\|1896702_1898331_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003616740.1\|1898561_1900190_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003616729.1\|1902012_1902663_-	HD domain-containing protein	NA	NA	NA	NA
WP_003616726.1\|1902829_1903000_+	hypothetical protein	NA	NA	NA	NA
WP_002877198.1\|1903446_1903629_-	cytochrome c551	NA	NA	NA	NA
WP_095439295.1\|1904110_1905316_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_16

2019733 : 2101129

Bacillus_phage(15.79%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439311.1\|2019733_2020996_-\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	4.2e-54	44.2
WP_095439277.1\|2021571_2022606_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	5.5e-52	34.4
WP_003616558.1\|2022828_2025075_-	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.8e-61	30.4
WP_035182882.1\|2027071_2027680_-	nitroreductase family protein	NA	NA	NA	NA
WP_003616550.1\|2027828_2030360_-	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	6.9e-72	25.1
WP_003616548.1\|2030535_2030754_+	hypothetical protein	NA	NA	NA	NA
WP_003616546.1\|2031057_2031975_+	hypothetical protein	A0A0E3XCL7	Enterococcus_phage	3.2e-19	67.1
WP_003616543.1\|2032145_2033093_+	DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_095439312.1\|2033311_2034574_+\|transposase	IS3-like element ISL6 family transposase	A0A1B1P773	Bacillus_phage	1.9e-54	45.2
WP_003616539.1\|2034832_2035834_+	C69 family dipeptidase	NA	NA	NA	NA
WP_003616536.1\|2035827_2036139_+	hypothetical protein	NA	NA	NA	NA
WP_003616535.1\|2036313_2037732_-	DASS family sodium-coupled anion symporter	NA	NA	NA	NA
WP_003613167.1\|2037757_2039161_-	class II fumarate hydratase	NA	NA	NA	NA
WP_003616531.1\|2039678_2039903_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_148465380.1\|2040146_2040371_-	hypothetical protein	NA	NA	NA	NA
WP_057727112.1\|2040641_2041556_+	hypothetical protein	NA	NA	NA	NA
WP_003616523.1\|2041614_2041854_-	hypothetical protein	NA	NA	NA	NA
WP_003616522.1\|2041950_2042451_-	O-acetyl-ADP-ribose deacetylase	F1SVT2	Red_sea_bream_iridovirus	7.0e-37	47.6
WP_003616516.1\|2043347_2044928_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.8e-15	24.5
WP_003616510.1\|2047746_2049237_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	3.1e-96	41.0
WP_003616508.1\|2049405_2050164_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_003616503.1\|2051902_2052571_+	cobyric acid synthase	NA	NA	NA	NA
WP_035161674.1\|2052765_2053002_+	hypothetical protein	NA	NA	NA	NA
WP_003614608.1\|2057420_2058089_-\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	5.7e-50	49.8
WP_080553986.1\|2058263_2058977_+	diguanylate cyclase	NA	NA	NA	NA
WP_003617868.1\|2059073_2059928_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_035172677.1\|2061834_2062032_+	hypothetical protein	NA	NA	NA	NA
WP_003616492.1\|2062973_2063171_+	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	1.9e-17	65.1
WP_003616489.1\|2063705_2063948_+	recombinase family protein	M4QQC6	Vibrio_phage	1.4e-06	55.8
WP_003613384.1\|2066318_2067128_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_035182879.1\|2067192_2068068_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003616481.1\|2068060_2069371_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_003616476.1\|2075191_2075461_-	anion permease	NA	NA	NA	NA
WP_169845243.1\|2075400_2075622_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_016396126.1\|2075682_2075865_+	hypothetical protein	NA	NA	NA	NA
WP_003616470.1\|2076250_2076715_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.5e-25	45.0
WP_013440306.1\|2076729_2077908_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.8e-98	47.1
WP_003616467.1\|2077927_2078542_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.6e-30	40.9
WP_003616462.1\|2086081_2086708_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003616461.1\|2086711_2088712_-	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	4.4e-29	33.9
WP_016396121.1\|2088849_2089239_-	iron-sulfur cluster biosynthesis family protein	NA	NA	NA	NA
WP_003613653.1\|2089398_2089623_+	hypothetical protein	NA	NA	NA	NA
WP_003613649.1\|2089797_2091084_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_002879627.1\|2091073_2091316_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_003616459.1\|2091385_2092618_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	A0A125RNP0	Pseudomonas_phage	5.4e-22	27.0
WP_035182877.1\|2092614_2094117_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	3.4e-42	28.5
WP_003613642.1\|2094132_2094282_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_003616457.1\|2094474_2094777_-	hypothetical protein	NA	NA	NA	NA
WP_003616456.1\|2094813_2096022_-	hypothetical protein	NA	NA	NA	NA
WP_003616454.1\|2096619_2097090_+	CBS domain-containing protein	NA	NA	NA	NA
WP_003616453.1\|2097250_2099065_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.5e-63	28.3
WP_035165557.1\|2099226_2100387_+	cation:proton antiporter	NA	NA	NA	NA
WP_003616451.1\|2100472_2101129_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_17

2125814 : 2134175

Lactobacillus_virus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095439199.1\|2125814_2127182_-\|transposase	ISL3-like element ISLdl1 family transposase	A4PE56	Ralstonia_virus	4.2e-31	29.1
WP_157737572.1\|2127447_2128584_+\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	9.1e-24	28.3
WP_003611191.1\|2128811_2129459_+	deoxynucleoside kinase	Q5ULP7	Lactobacillus_virus	1.2e-49	49.8
WP_003611175.1\|2129480_2130179_+	deoxynucleoside kinase	Q5ULP7	Lactobacillus_virus	1.0e-54	49.8
WP_003616420.1\|2130422_2131880_+	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_003616418.1\|2131899_2132646_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-27	37.1
WP_003616417.1\|2132864_2134175_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.0e-51	31.7

Anti-CRISPR protein detection

Acr_ID: NZ_CP022988.1|WP_003616548.1|2030535_2030754_+|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP022988.1|WP_003616548.1|2030535_2030754_+|hypothetical-protein

2030535_2030754_+

72 aa aa

2019733-2101129

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP022988_1	TypeV	1.4\|284879\|18\|NZ_CP022988\|CRT	284879-284896	18	2025804-2025787	2

1. spacer 1.4|284879|18|NZ_CP022988|CRT matches to NZ_CP022988 position: 2025804-2025787, mismatch: 2

gatgcaaagaaggcaacc	CRISPR spacer
gatgcaaagaatgtaacc	Protospacer
*********** *.****

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022988

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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