CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP029612	Enterococcus faecalis strain H25 chromosome, complete genome	3 crisprs	csa3,cas3,cas14j,DinG,DEDDh	1	3	15	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP029612_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029612_1

1901683-1901982

Orphan

NA:II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	CRISPRCasFinder
AAACAACATGACTCTAAAAC	CRT
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	PILER-CR

4 spacers

The CRISPR arrays of NZ_CP029612_1

>merge|NZ_CP029612|1|1901683-1901982|CRISPRCasFinder,CRT,PILER-CR
GTGATAGTTTGTTTTTTAACAACATGACTCTAAAACGATTCCGAGTGATTCACTTTTAGCTTGTTCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAACGTTTTTAGGGATCCAAATACCTTTAAAGTTTTGGTACCATTCCAAACAACATGACTCTAAAACAGAGACAGCGGGAAAACTACGATATTCATCGTTTTGGTACCATTCCAAACAACATGACTCTAAAACCAATGTGTCTGCATTGATATGCTGAGAAATGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP029612|1|1|1901683-1901982|CRISPRCasFinder
GTGATAGTTTGTTTTTTAACAACATGACTCTAAAAC	GATTCCGAGTGATTCACTTTTAGCTTGTTC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AACGTTTTTAGGGATCCAAATACCTTTAAA
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	AGAGACAGCGGGAAAACTACGATATTCATC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	CAATGTGTCTGCATTGATATGCTGAGAAAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP029612|1|1|1901699-1901982|CRT
TAACAACATGACTCTAAAAC	GATTCCGAGTGATTCACTTTTAGCTTGTTCGTTTTGGTACCATTCT
AAACAACATGACTCTAAAAC	AACGTTTTTAGGGATCCAAATACCTTTAAAGTTTTGGTACCATTCC
AAACAACATGACTCTAAAAC	AGAGACAGCGGGAAAACTACGATATTCATCGTTTTGGTACCATTCC
AAACAACATGACTCTAAAAC	CAATGTGTCTGCATTGATATGCTGAGAAATGTTTTGGTACCATTCT
AAACAACATGACTCTAAAAC

>NZ_CP029612|1|1|1901749-1901982|PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AACGTTTTTAGGGATCCAAATACCTTTAAA
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	AGAGACAGCGGGAAAACTACGATATTCATC
GTTTTGGTACCATTCCAAACAACATGACTCTAAAAC	CAATGTGTCTGCATTGATATGCTGAGAAAT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029612.1\|WP_002356974.1\|1899857_1901276_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP029612.1\|WP_002360016.1\|1893259_1894165_-\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP029612.1\|WP_095714916.1\|1895346_1897113_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP029612.1\|WP_002380449.1\|1892019_1893231_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP029612.1\|WP_002362076.1\|1911478_1912453_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_CP029612.1\|WP_002356959.1\|1909764_1910109_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_CP029612.1\|WP_002360011.1\|1906996_1908235_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP029612.1\|WP_002360015.1\|1894286_1895267_+\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP029612.1\|WP_002380452.1\|1903087_1905169_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP029612.1\|WP_002380448.1\|1889282_1891706_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP029612.1\|WP_002362075.1\|1908414_1909539_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP029612.1\|WP_002381711.1\|1887583_1888333_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP029612.1\|WP_002378485.1\|1910176_1911322_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP029612.1\|WP_002379584.1\|1905762_1906332_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP029612.1\|WP_002356963.1\|1906464_1906980_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP029612.1\|WP_002356976.1\|1898847_1899861_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP029612.1\|WP_002364244.1\|1888450_1889152_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP029612.1\|WP_002356966.1\|1905299_1905665_-\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NZ_CP029612.1\|WP_002380451.1\|1902139_1903003_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP029612.1\|WP_002378477.1\|1897109_1898843_-\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323

Protein	Function_ID	Function_description	E-value
NZ_CP029612.1\|WP_002356974.1\|1899857_1901276_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_CP029612.1\|WP_002360016.1\|1893259_1894165_-\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NZ_CP029612.1\|WP_095714916.1\|1895346_1897113_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP029612.1\|WP_002380449.1\|1892019_1893231_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	5.21914e-122
NZ_CP029612.1\|WP_002362076.1\|1911478_1912453_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_CP029612.1\|WP_002356959.1\|1909764_1910109_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NZ_CP029612.1\|WP_002360011.1\|1906996_1908235_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.24866e-173
NZ_CP029612.1\|WP_002360015.1\|1894286_1895267_+\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.52576e-80
NZ_CP029612.1\|WP_002380452.1\|1903087_1905169_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP029612.1\|WP_002380448.1\|1889282_1891706_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	2.52612e-175
NZ_CP029612.1\|WP_002362075.1\|1908414_1909539_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP029612.1\|WP_002381711.1\|1887583_1888333_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.63593e-110
NZ_CP029612.1\|WP_002378485.1\|1910176_1911322_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	1.04062e-178
NZ_CP029612.1\|WP_002379584.1\|1905762_1906332_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.88451e-15
NZ_CP029612.1\|WP_002356963.1\|1906464_1906980_+\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	5.73504e-32
NZ_CP029612.1\|WP_002356976.1\|1898847_1899861_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
NZ_CP029612.1\|WP_002364244.1\|1888450_1889152_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.52313e-37
NZ_CP029612.1\|WP_002356966.1\|1905299_1905665_-\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NZ_CP029612.1\|WP_002380451.1\|1902139_1903003_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.22379e-26
NZ_CP029612.1\|WP_002378477.1\|1897109_1898843_-\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0

>NZ_CP029612.1|WP_002356974.1|1899857_1901276_-|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NZ_CP029612.1|WP_002356976.1|1898847_1899861_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NZ_CP029612.1|WP_002378477.1|1897109_1898843_-|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGITLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATMSTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NZ_CP029612.1|WP_095714916.1|1895346_1897113_-|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYVALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEQQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVTQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NZ_CP029612.1|WP_002360015.1|1894286_1895267_+|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFSPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NZ_CP029612.1|WP_002360016.1|1893259_1894165_-|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NZ_CP029612.1|WP_002380449.1|1892019_1893231_-|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVNEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NZ_CP029612.1|WP_002380448.1|1889282_1891706_-|DNA-translocase-FtsK
MAQKRSTNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLLFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAAERLTKTPVETHQPMVEEPATPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAAPETPEQ
>NZ_CP029612.1|WP_002364244.1|1888450_1889152_-|GntR-family-transcriptional-regulator
MRRKSVLYLEVADQIKEDILSGKYPVGTFLPTETELEELFNVSKITIRRAIEMLATEEFVEKKSGRGTTVLSNRPYNKLSKAGTFTEFLNESGQKVTKKVLQVENLTLSKEMPAYQFLGEEVVHLSRLYLIDEQPYIYFNYYLPAAMKDVSLTEYKEESLYRLMDRHAIEIYKFEDRFEVATLTEAEQKMLQTTETTGLKRIRRSLSPTGRCVEYSEAIYNTKIHPYVIEYEA
>NZ_CP029612.1|WP_002381711.1|1887583_1888333_-|ABC-transporter-ATP-binding-protein
MLEVQNLKKVYGNEIKYEALKGINLTVQDGEFIGIMGPSGSGKSTLLNLLATIDSPTDGEILLNGKNPNNLNQEQIAKFRRTELGFVFQSFNLMPTLTVEENIILPLTLDGEKVSVMKRQLAELSERLGINHLLKKRIAEISGGQAQRVAVARAMIHHPQLLLADEPTGNLDTKSSKDVMGLLQQLNEEEAATILMVTHDPLAASYCKRIVFIKDGELIDEIVQNGNQKEFYDLIMVKLAEIEGVDNEF
>NZ_CP029612.1|WP_002380451.1|1902139_1903003_-|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFIAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWSGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIMELAQRITPQQRAEMHTFDDIYPHQVVNASFDFQEGRTTEGGEMTHMIGFATSQENTYKDLEQLSVPTHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NZ_CP029612.1|WP_002380452.1|1903087_1905169_-|DNA-topoisomerase-III
MVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSISAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NZ_CP029612.1|WP_002356966.1|1905299_1905665_-|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NZ_CP029612.1|WP_002379584.1|1905762_1906332_-|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIVSLEVAG
>NZ_CP029612.1|WP_002356963.1|1906464_1906980_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQLLAKAKFEFLY
>NZ_CP029612.1|WP_002360011.1|1906996_1908235_+|multidrug-efflux-MFS-transporter
MYELIKSKIFRPRQPWEKNLLVLWFGTFMAGIGFSLVMPFMPLYINTLGTFTHQQLNFWSGITFSSTFLVTTIVSPWWGRLADRKGRKLMLLRASLGMAIVISLMGAVTSVYQLIGLRLLQGVFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTLLGPLLGGVTASIFGYRPTFFITGTILLLVFVLSLVFVHEEFVPIEKNQAASGKQILKKLEHPHVILGMFITTLIIQASNNSISPIISLYIQQLLGGHGNVTLISGVIASIPGIATLIAAPRFGRLGDRIGSERILTIGLILAIFVYLPMAFVQNVWQLAMLRFLVGISDACLLPAVQTLITRYSPSDAAGRIFSYNQSFQATGNVIGPMIGSSVSAAFGYRGVFISTSCLVLINLLWVRRSTAELKKEKNDA
>NZ_CP029612.1|WP_002362075.1|1908414_1909539_-|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>NZ_CP029612.1|WP_002356959.1|1909764_1910109_-|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NZ_CP029612.1|WP_002378485.1|1910176_1911322_-|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQMIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGIPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NZ_CP029612.1|WP_002362076.1|1911478_1912453_-|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTADRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE

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Crispr_ID: NZ_CP029612_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029612_2

2182136-2182249

Orphan

Consensus_repeat	Method
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029612_2

>merge|NZ_CP029612|2|2182136-2182249|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTCCACATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAGACAACGTTCCCTTTGGTCACCTTGTACTGTTC

>NZ_CP029612|2|2|2182136-2182249|CRISPRCasFinder
ACAACGTTCCCTTTGGTCACCTTGTGCTGTTC	CACATCTACTCCATGTTTTTGGCTAAGCAGTTTGTTTTAACATAGAGGAG
ACAACGTTCCCTTTGGTCACCTTGTACTGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029612.1\|WP_095714921.1\|2185215_2187414_-\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397
NZ_CP029612.1\|WP_002380582.1\|2174886_2175672_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP029612.1\|WP_002379669.1\|2180920_2181829_-\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
NZ_CP029612.1\|WP_002356761.1\|2172916_2173639_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NZ_CP029612.1\|WP_095714920.1\|2183435_2184338_-\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_CP029612.1\|WP_002356741.1\|2188599_2189049_-\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP029612.1\|WP_002356748.1\|2182564_2183353_-\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
NZ_CP029612.1\|WP_002356760.1\|2173899_2174781_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP029612.1\|WP_002356735.1\|2189981_2190812_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|377080
NZ_CP029612.1\|WP_002356753.1\|2178603_2178795_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_CP029612.1\|WP_002356756.1\|2177195_2177471_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|224174
NZ_CP029612.1\|WP_002387080.1\|2189416_2189857_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NZ_CP029612.1\|WP_002380585.1\|2184736_2185216_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NZ_CP029612.1\|WP_002370425.1\|2178834_2180919_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NZ_CP029612.1\|WP_002389231.1\|2187442_2188417_-\|phosphate-starvation-inducible-protein-PhoH	unknown	unknown	gnl\|CDD\|224616
NZ_CP029612.1\|WP_002356755.1\|2177637_2178570_+\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
NZ_CP029612.1\|WP_002367049.1\|2175855_2176293_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CP029612.1\|WP_002356746.1\|2184351_2184759_-\|diacylglycerol-kinase-family-protein	unknown	unknown	gnl\|CDD\|260134
NZ_CP029612.1\|WP_002356740.1\|2189074_2189251_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP029612.1\|WP_002380583.1\|2176312_2177089_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640

Protein	Function_ID	Function_description	E-value
NZ_CP029612.1\|WP_095714921.1\|2185215_2187414_-\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	1.80428e-158
NZ_CP029612.1\|WP_002380582.1\|2174886_2175672_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	8.65565e-166
NZ_CP029612.1\|WP_002379669.1\|2180920_2181829_-\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP029612.1\|WP_002356761.1\|2172916_2173639_-\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	1.02758e-148
NZ_CP029612.1\|WP_095714920.1\|2183435_2184338_-\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	4.35298e-180
NZ_CP029612.1\|WP_002356741.1\|2188599_2189049_-\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.89434e-63
NZ_CP029612.1\|WP_002356748.1\|2182564_2183353_-\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	6.18949e-71
NZ_CP029612.1\|WP_002356760.1\|2173899_2174781_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.02636e-146
NZ_CP029612.1\|WP_002356735.1\|2189981_2190812_+\|kinase/pyrophosphorylase	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	3.91447e-139
NZ_CP029612.1\|WP_002356753.1\|2178603_2178795_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	6.66934e-06
NZ_CP029612.1\|WP_002356756.1\|2177195_2177471_+\|acylphosphatase	gnl\|CDD\|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	1.58992e-26
NZ_CP029612.1\|WP_002387080.1\|2189416_2189857_-\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	4.90593e-35
NZ_CP029612.1\|WP_002380585.1\|2184736_2185216_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	8.00786e-61
NZ_CP029612.1\|WP_002370425.1\|2178834_2180919_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_CP029612.1\|WP_002389231.1\|2187442_2188417_-\|phosphate-starvation-inducible-protein-PhoH	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	4.35931e-144
NZ_CP029612.1\|WP_002356755.1\|2177637_2178570_+\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	1.42463e-134
NZ_CP029612.1\|WP_002367049.1\|2175855_2176293_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.03251e-32
NZ_CP029612.1\|WP_002356746.1\|2184351_2184759_-\|diacylglycerol-kinase-family-protein	gnl\|CDD\|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	2.85033e-42
NZ_CP029612.1\|WP_002356740.1\|2189074_2189251_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.30263e-11
NZ_CP029612.1\|WP_002380583.1\|2176312_2177089_-\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.51292e-71

>NZ_CP029612.1|WP_002379669.1|2180920_2181829_-|glycine--tRNA-ligase-subunit-alpha
MKNKLTVQEMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLKLLGIDPLEHDIRFVEDNWENPSMGCAGLGWEVWLDGMEITQFTYFQQVGGLQCHPVTSEITYGLERLASYIQEVESVYDLEWTQGVKYGEIFVQPEYEHSKYSFEISNQEMLLENFDKFEKEAKRCIEESLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNMARSVAKIFVAEREKLGFPLLNKDQSVSKEAE
>NZ_CP029612.1|WP_002370425.1|2178834_2180919_-|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGLEEMPAHVVTPSRIQLEEKVIKFLDEHHLDYETVQSFATPRRLAVKVTAIPEKQADVEEEVKGPAKKIALDAEGNWSKAAQGFVRGQGVTTEDIVFKELNGVEYVYVTKFTKGQSAKEVLTKLNDVITSLTFPVTMHWANYDFEYIRPIHWIVALLDDEVIPFKVLDVTTGQTSRGHRFLGDDVTFQHANEYEAKLKEQFVVVQPNERKQMIVDQANALAAEKNWQLALDEELLEEVTNLVEYPTAFVGSFDEKYLSVPDEVLVTSMKEHQRYFEVRNDQGLLMPHFIAVRNGDNVHLENVIKGNEKVLIARLEDAEFFYNEDKKLTIEACVEKLKNVTFHEKIGSIYEKMQRVALIAQIIGRKVGLSEEELEDLKRASEIYKFDLVTNMVGEFPELQGIMGEKYALLQGEKPAVATAIREHYLPTSSEGELPETAIGAVLALADKLDSVFSFFSVGMIPTGSNDPYALRRQTYGVIRIIEDKGWTFPLVQLQTEVDEAVNQDVEKYGVLLNEGQAEVVEFVKARLRQLLMTKNVRHDIIDAVVSAEQADLSKLFASANILKSRFEDQDFKPSMEALTRVINLAKKGQELLGDTEEGIDPSLFENKAEKELYQAVNDLSEAFATRTIAENYEALVNLRPLIDAYFNETMVMVEDEKVKQNRLKQLMQIAKMALSIASLDLLIVK
>NZ_CP029612.1|WP_002356753.1|2178603_2178795_-|hypothetical-protein
MLETTFEQILTQLSKPAVRALTNEKIDSVDELYARGRKALLSLHGFGPKSIRTIEEMTGKELK
>NZ_CP029612.1|WP_002356755.1|2177637_2178570_+|membrane-protein-insertase-YidC
MRKLNRWLYGSGLLFLVMFLSGCVKTGADGQPTGEGFVYNFLVLPMSNAITYLVDNFNWNYGWAIIFITIIVRIIILPLGLHQSKKSFIQTEKMQAIKPQVDVAQAKMKQASTREEQMAAQAELQKIYKENNVSMVGGIGCLPLLIQMPIFSSLFFAARYTKGIATASFLGMNLGQPNMILVALAGLAYLAQGYISMIGIPEEQKKTMKSMLIVSPLMIVFMSFSSPAGVALYWVVGGIFTCIQSAITNILLRPRIKKQVQEELKNNPPKQVVTPIKDVTPKETNKVTQKTNQPKANGNKGRNAGKQKRK
>NZ_CP029612.1|WP_002356756.1|2177195_2177471_+|acylphosphatase
MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVKNEDDGSVSITAIAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
>NZ_CP029612.1|WP_002380583.1|2176312_2177089_-|RNA-methyltransferase
MKEITSTKNNQLKEWKKLHKKKYREELNQYIIEGFHLIEEAVKANADVQWILFNQRGQQEWGTWLAEQETEKLIFVSDEVLNSLSELPTSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVLQRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMFYFENNQ
>NZ_CP029612.1|WP_002367049.1|2175855_2176293_-|GNAT-family-N-acetyltransferase
MLTIKKTTQLTEKELETIMAIWLQTNLEAHPFVAPTYWQENKAFVRAALPKATLILAEEEGQIIGFLGLMDNYIAGIFIKKAFQGKGIGQKLLQVAKEEQDLLSLAVYRKNQAAYAFYQKQGFVQQKRTIDETGNEECHLVWQAQ
>NZ_CP029612.1|WP_002380582.1|2174886_2175672_-|30S-ribosomal-protein-S2
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGIFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
>NZ_CP029612.1|WP_002356760.1|2173899_2174781_-|elongation-factor-Ts
MADVTAKMVKELRDMTGVGMMDAKKALVKVEGDMEKAVDFLRENGMAKAAKKNDRIAAEGLANVATVGNVAAIVEVNSETDFVSKNEMFQDLVKDIATKVAENKPATMEEAMAIKTEKGTIESDLIEATTVIGEKISFRRFEVVEKADNAAFGAYLHMGGRIAVLTVIDGTTDEEVAKDVAMHIAAINPRYVNESQIPQEELEHEKAVLTEQALNEGKPANIVEKMVVGRLQKFKAEIALVDQPFVKDPDMTVEKFVASKGGEVKSFVRFEVGEGIEKREDNFADEVMSQMKN
>NZ_CP029612.1|WP_002356761.1|2172916_2173639_-|UMP-kinase
MVKPKYQRVVLKLSGEALAGEDGFGIKPPVIKEIVQEIKEVHELGIEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENLGVPTRVQTSIEMRQIAEPYIRRRAERHLEKGRVVIFAGGTGNPYFSTDTTAALRAAEVDADVILMAKNNVDGVYSADPRVDETATKFEELTHLDVISKGLQVMDSTASSLSMDNDIPLVVFNLNEAGNIRRAILGENIGTTVRGK
>NZ_CP029612.1|WP_002356748.1|2182564_2183353_-|DNA-repair-protein-RecO
MALGETKGIILFTKDFKEKDKLVKIFTESYGKLMFFVKGAHRKNNPLLPAILPFTEAVYIGNFREEGLSFLNSSKEVQPFRNIQQDIFINAYGTYILNLVDAAIEDQHYDPNLFQFTHMALSALNEQKDPEIITNIFEIQLLERFGVRPEWHHCVACGETQGKFDYSSKYSGVLCEKHWHLDEQRYHADPRAIHFIRLFAQVSYEKVQNIQVKEETKKSIRETIDMLYDEYVGLHLKSKKFIDQMKTWENTLKIPPRKKEEK
>NZ_CP029612.1|WP_095714920.1|2183435_2184338_-|GTPase-Era
MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSTDQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
>NZ_CP029612.1|WP_002356746.1|2184351_2184759_-|diacylglycerol-kinase-family-protein
MRMALKDEQTGKNKHFINSLEFAWQGIKTVFREERNMRKHVAFGVTAIVFGFLFSLTLAEWLWLLLAVFLVWLAEIINTIFENVVDMFTDFHFHPIGKKVKDMAAGAVLLTAGFAVLVGLILFVPKILQIIQMWK
>NZ_CP029612.1|WP_002380585.1|2184736_2185216_-|rRNA-maturation-RNase-YbeY
MDITFIDETEKVPTEEIKEIENLLQFAAGFLEIAEDTEMSVTFTDNAGIQVINRDYRGKDMPTDVISFALEDEGENELPIIFDDEELAELPRNLGDLIISTERAAEQAVEYGHTLEREMGFLAVHGFLHLNGYDHMEPEDEKEMFGLQKEILDAYGLKR
>NZ_CP029612.1|WP_095714921.1|2185215_2187414_-|HDIG-domain-containing-protein
MKKVLTKLGDRLGKAYLPILLAVFSLLLFMIMFGSVHQKRVEIKEGQLAEKTIRANKNIENTYETEQRKKLAAEAVTPEYIYQEDTASVQHNRIDKLFKLIDSANEKVDKEYSNKQAKAKKEETIPAPTVEERVASLKSLFESLPQDEVAFYQSFPNVFYQTIFTLTSEQLDKVRSESLMLVDDAMQNHVRESDLDKIRQEANGKIQYLDITSTMQQVIRYIVNQGIVVNDIANEKRTEELRQKAMNAVQPAMIYQGEIIVREGTQIDAKAVEKLELLGMTSQNTSIFPMVALALAILLQVEVLIFFTKQVTEPSRQRSFIIFYTGAMLISVILMKFFQIFQTEQLMYIPLFYPAAFAPLILNHFVNRRSGIIAAIFQVVFALFIFYNSIGTNSLTVILIMYLFSGFLATVVKRKRMSEQVFPALMWVVVFPVFMAVVLMIYQGMSLTDGKTWTALICASAGTVLSFLATMGLHPYIELLVTDDSMIVLNELSNPNHPLLKQLLEEAPGTYHHSMMVASLSANAVAEIGGRSLLTRVACYYHDIGKIKHANFFVENLPAGAENPHNFLLPEDSKQIIFGHVIDGAKILEEYNMPQMVIDICRQHHGTTLMKFFYVKAKERNPEIKESDFRYPGPRPQTREAGIVSIADTCEAAVRAMDHPTNEKIQAFVHNVIQDRISDGQLDECGLTMKEIRIIEKSLINGLCSTFHSRIKYPKMKAEAEEMKDEQEKRDD
>NZ_CP029612.1|WP_002389231.1|2187442_2188417_-|phosphate-starvation-inducible-protein-PhoH
MTDNQSKSLELILTDSDDAHMLLGTHDKHIKFLEENTHVTINSRGEVIQLIGESSEVELVASVLRALQTLIQRGIKVHTPDVVSALKMAKAGNLEAFIAMYEEEIMKDHHGRAIRIKNVGQKKYIDAVKTHDVIFGVGPAGTGKTFLAVVMAVAALKKGEVQKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQIFGMDHTNRLMERGVIEIAPLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGFSSKMIVNGDTSQIDLPRGVTSGLVNAERTLKDIEKIAFVNFEASDVVRHPVVAQIIQAYEKEQQKHS
>NZ_CP029612.1|WP_002356741.1|2188599_2189049_-|GatB/YqeY-domain-containing-protein
MSLLTTLNDDIKTAMKAKDKETLAVLRMLKTAIQNDQIKAGRELNGEEELTVLSREMKQRKDSLSEFEKAGRDDLVEKVKVEIAIVEKYMPQQLTEEEIRQLVQEVMTQTGATSPKDFGKVMGAMMPKVKGKADGNQVNAIVKELLQEN
>NZ_CP029612.1|WP_002356740.1|2189074_2189251_-|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
>NZ_CP029612.1|WP_002387080.1|2189416_2189857_-|transcriptional-repressor
MAMAPVKTNIEQALETMKASGLKYTKKRELLMSYLIKRNRYVSAREVYEFMNETFKGVSYDTVYRNLHDFERLELLEKTELNGEQKFRFRCCQEVEHHHHFICTVCGKTEEIHMCPMNFFEEQLKGCSIEGHRFEILGRCADCCEK
>NZ_CP029612.1|WP_002356735.1|2189981_2190812_+|kinase/pyrophosphorylase
MTIFVISDSAGETASKLAAASMAQYPTVDFTLIRRTFVKDEDKLVQALEDAKKAEAMVLHTIINDHLVAIANQFFNEHQLFHFDILTPPVAEIERLTGVAPMREPGALHHLNENYFKRIEAMEFAVKYDDGKDPRGFLEADVLLLGVSRTSKTPLSLFLANKNLKVANLPLIPEAHLPKQLFEMDPKKIVGLTNDPNVLNGIRKERMRAYGLPENTSYSDIEKIRRELAFANDLYQKLGCIVIDVASLSIEETASMILNALNLEDHSYYSTETSED

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Crispr_ID: NZ_CP029612_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029612_3

2703893-2703971

Orphan

Consensus_repeat	Method
GTAGGTTCTGGGGTAGGTGTTGGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029612_3

>merge|NZ_CP029612|3|2703893-2703971|CRISPRCasFinder
GTTGGATCTGGGGTAGGTTCTGGGGTAGGTGTTGGTTCTGGCGTTGGACCCGGAGCTGGTGTCGGATTAGGCGTTGGTT

>NZ_CP029612|3|3|2703893-2703971|CRISPRCasFinder
GTTGGATCTGGGGTAGGTTCTGGGG	TAGGTGTTGGTTCTGGCGTTGGACCCGGA
GCTGGTGTCGGATTAGGCGTTGGTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029612.1\|WP_002394269.1\|2710395_2710689_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002410060.1\|2707139_2707547_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_095715025.1\|2698087_2698477_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372239
NZ_CP029612.1\|WP_002371426.1\|2707556_2707844_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002371429.1\|2709639_2710020_-\|DUF86-domain-containing-protein	unknown	unknown	gnl\|CDD\|366864
NZ_CP029612.1\|WP_002371421.1\|2700822_2703570_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|380024
NZ_CP029612.1\|WP_002371416.1\|2698485_2698710_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002393064.1\|2691794_2692823_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380090
NZ_CP029612.1\|WP_002380870.1\|2699676_2700144_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002393071.1\|2710009_2710336_-\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|376187
NZ_CP029612.1\|WP_002380872.1\|2708130_2709639_-\|cell-division-protein-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP029612.1\|WP_002393069.1\|2704846_2705458_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002371434.1\|2711109_2711298_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002371410.1\|2694932_2697437_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|315512
NZ_CP029612.1\|WP_095715024.1\|2692865_2694917_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376803
NZ_CP029612.1\|WP_002393070.1\|2705535_2706819_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367101
NZ_CP029612.1\|WP_002371420.1\|2700140_2700683_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002371413.1\|2697700_2698009_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029612.1\|WP_002371418.1\|2698709_2699696_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372237
NZ_CP029612.1\|WP_002371427.1\|2707833_2708112_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP029612.1\|WP_095715025.1\|2698087_2698477_-\|conjugal-transfer-protein	gnl\|CDD\|372239	pfam12648, TcpE, TcpE family. This family of proteins includes TcpE a conjugative transposon membrane protein.This family of proteins is found in bacteria. Proteins in this family are typically between 122 and 168 amino acids in length.	1.32285e-20
NZ_CP029612.1\|WP_002380872.1\|2708130_2709639_-\|cell-division-protein-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.91967e-23
NZ_CP029612.1\|WP_002371429.1\|2709639_2710020_-\|DUF86-domain-containing-protein	gnl\|CDD\|366864	pfam01934, DUF86, Protein of unknown function DUF86. The function of members of this family is unknown.	4.23382e-09
NZ_CP029612.1\|WP_002371421.1\|2700822_2703570_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|380024	pfam17802, SpaA, Prealbumin-like fold domain. This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.	1.08352e-09
NZ_CP029612.1\|WP_002371410.1\|2694932_2697437_-\|ATP-binding-protein	gnl\|CDD\|315512	pfam12846, AAA_10, AAA-like domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	2.06494e-150
NZ_CP029612.1\|WP_095715024.1\|2692865_2694917_-\|hypothetical-protein	gnl\|CDD\|376803	pfam02508, Rnf-Nqr, Rnf-Nqr subunit, membrane protein. This is a family of integral membrane proteins including Rhodobacter-specific nitrogen fixation (rnf) proteins RnfA and RnfE and Na+-translocating NADH:ubiquinone oxidoreductase (Na+-NQR) subunits NqrD and NqrE.	0.00182883
NZ_CP029612.1\|WP_002393070.1\|2705535_2706819_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|367101	pfam02486, Rep_trans, Replication initiation factor. Plasmid replication is initiated by the replication initiation factor (REP). This family represents a probable topoisomerase that makes a sequence-specific single-stranded nick in the plasmid DNA at the origin of replication. Human proteins also belong to this family, including myelin transcription factor 2 and cerebrin-50.	2.50501e-59
NZ_CP029612.1\|WP_002393064.1\|2691794_2692823_-\|CHAP-domain-containing-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	2.85629e-35
NZ_CP029612.1\|WP_002371418.1\|2698709_2699696_-\|conjugal-transfer-protein	gnl\|CDD\|372237	pfam12642, TpcC, Conjugative transposon protein TcpC. This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.	4.05254e-58
NZ_CP029612.1\|WP_002393071.1\|2710009_2710336_-\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	1.00944e-12

>NZ_CP029612.1|WP_002371421.1|2700822_2703570_-|LPXTG-cell-wall-anchor-domain-containing-protein
MKFSRKIKNLAMIGVIGLQTLFTAVPVNAVTASDVSFDHNNEREMSVTWKGETRDIWTAPIYLDQGTGKELVFCVDPFSHVLEGTGYSSNPFALNRKANLISSLWNLAGTDLDTMFVAQEMLYNEVGAVVHSNGDLTEEQRMTIKKKINDVIANYEKQPSFHNSKVKLTLGESTVLTDTNGSNLSQFDVVAQNTANVDFRQSGNKLTITPKSTANSSGTLILKKSLREGTPFIWKKSGSQELISSGVSDPSKYKIDFEIVTTGEMKIVKLDKETGKPVPNTKFEVEYNGKKQTVTTDTKGEAIVKNIPHNAKVKATEIFVPAPYVLDKNNTKEVVVKAGKTASVEFKNEVATGKTTLIKEDKTTNSDKPLNPTYPMVGAKYGLFKENGTLLKEFTLDEKLTASMDKLDLGTYYWQETEAPAGYTLDPEKHVVELTYKDQNTPVVIKDSESIDDVIRMNLDGQKVIQNETNEIFKNGVEFTATNERTQEKTVVTTANVDGKNGYFKFGNLPIDDYIITETKGVEGYQSIDPIEVKHSYDKESDTFTFTVTDQKSGNVLNTEQFTQKDLSKGENVDLGTYTLKDKATPIDTPWVDIVSIAHTGDGKTRSFIWGKEVKLYDDVKISHTNIPLGTKRAFEDILVAVTPDNQEKDVWSSGKIDYKVANENMTQRVETNYDYKKDPEGTRYFFKVIGYSKVSDTEYKQDTEHNFDGNQKNQEIIPALPDKPEINISSQAHIGDNKTQTFIWGEKVKLYDNVKISHKNVDVDTERAFETILVAVTPDGKEKDAWTSGKVDYKVTKKDTVQTVQADYDYKKDLKGTRYYFKEIGYNKTKNNKYEKDSEHNIGGKEKTQDITSTVKEVPKKEPKTPSNPKQAEHGLLPYTGEEANIWLIGVGVVLLGSVYALVQYKKRKKHMNK
>NZ_CP029612.1|WP_002371420.1|2700140_2700683_-|hypothetical-protein
MVKELSKEEFVNQYMFDFKSLIFKSNNPEKITAKQEKLLECEMKIAVLFYETYRRMKGYPPDEKELGRIVQRNFLDRLKLFRVEYDVISEEKFCGLHVQMVKQQMPLEKYQADDLSYILGREKKVAANYFLTHDDFPTGYEELMISRSKKVVTHGLEELREKFMERYHKYYRKMERSCIL
>NZ_CP029612.1|WP_002380870.1|2699676_2700144_-|hypothetical-protein
MNQNIMPIFREHSKFYQKYSNVPVPEMLRLHGFIVDEMPIDEADIVYMEEYKNSLFKMGIIIDEAPFKKEFVAQYVFHGGITSLIAEGQYLRKPNGDKMYNSYYFYLYKEGFQTHKGHVRERVYVEKAIKSTFLKTFESCLGLLRVGGEYEFKEN
>NZ_CP029612.1|WP_002371418.1|2698709_2699696_-|conjugal-transfer-protein
MNLKKIKKKEKKEKTPKVKTFSQKKANRVVLIGASVLLVMSGVGALRANVMASNVDNLYSKVDTLSEQSKKNKVDREELDYSTLSFYVENFAKEYLNYNSKASDEAKKARIDRLSKYLSLDVKNVDETENLQGNVLRTFKNTSLSRIEKMEDCYLVYLNVNYELEKDKKTENVTQNMVLPIQVKDNLFSIVGRPYFVASSLPQGKTVPLKQTENSIDVDGKEKQSVEKFLKMFFTKYSVGNKQELMLLMKKPATTAGQDSFVSIDSGDMKFFDTKQKGVTGVQVSVTFSDNTTKLTHTEDFSLWLSKTENSYFINTMKHYFTEKEGND
>NZ_CP029612.1|WP_002371416.1|2698485_2698710_-|hypothetical-protein
MNTGNLSSFLSTGFITILASGAIILILKHWKGAEWAKIGSVIVIALILQDFATNQGKNIFAVVKWFLSLVGIKM
>NZ_CP029612.1|WP_095715025.1|2698087_2698477_-|conjugal-transfer-protein
MKYYDYSRGLKAPYSMQVIKSPKGQVVWVFAQPVSLSYLLILFLGIVLTGLFWKEVPLPQILGINLNLLIMLLMPNKVARRYSEKEFEGKTGFVFLKDGFVYVKNYVLDSRSIVAFERVKEIEEFSFKR
>NZ_CP029612.1|WP_002371413.1|2697700_2698009_+|hypothetical-protein
MRKENVIKFFLYILIPIIIGTIISLFTNAPIFLIAGIIYIILLLFLLPTLDFGITDFNAKQINPSYRPEKKINKNESIVTVLLLVIGIIVCTVMLYLKYKTS
>NZ_CP029612.1|WP_002371410.1|2694932_2697437_-|ATP-binding-protein
MQLEYPLTNHMKGNIVLTQEKTAIAYYRVRSETVMLTDVEKKLKTKRKVARALNRLKANDGFEINLLPVNADIRGKMGAMRSLIDSNNYEVGVDKLMKTAMVLEQEMGMVYEYTWIIGVPLIKKDLAVDLKETVTNSISNVSEKFVKGLGFDVELSECWEKDYREQELEVYQNLSELLIERLSEDELYYYQAYQFLKNIPHERQDVLSSQNLDNLMATKIKPLFGGGLHLNCDYGESYISYLPMGDVGVFLDGNHFLEVVQKMPFPVEVKIQATFAESKGQLALSGRSSRARTRTKNIMQEAHLAGSKQKRKIVEGQLSLDDLDQKIDDGVDIIDWKAVVVVSGSTKKQMRARKKYLINRFDSLDIPLIKATFDNPYLFQSTLFGNFIRMQTSRWQHTSTIESFAELNFFTSLHAGTKLGFYLGRIDTTLEEKEDRKSIISSSKNLIFMNMLLANKQNVDGKKTNNPHWALTGDTGNGKSVTAKTLFMQMALLKDRVLYIDPKKEMRKQFMYTINAPEYQKKYPLDVDFVKSFNFVTLDVRDTKNHGVLDPIVLFNETEATSTAKAMITNVYDGTWNLKQKTASNEAITKVISERKAGKKVGFWHVIELLAESEISDVKDMGRFLLSTIKGSVLELAFSHGEVEGLSFDRKVTILEIEDLDLPTDKNEKLDENKRSSVTLMFALGTFCSKFGSRNPKEETVTFFDESWIFQSSPEGKAILKSMKRIGRSFNNFLVLITQSTNDLDDSEDGTGFGTVICFDEVQNREGVLKYLNLPVNEINMKWVSNMVQGQCLMKDMFGQTNRIVVHVIFEEWLELFKTVDDTEASKMENRFVA
>NZ_CP029612.1|WP_095715024.1|2692865_2694917_-|hypothetical-protein
MQYLIDSYSAYTVDGGLLDKGWQVVNWFFVDIPFFILRTFASFFLFCENVLNRSSFFEGKQETVLNMSKDVLNDFGGKGFRGSSLFALAILVSAYYLLYHFFSSRRNFSKVFLHYLAVVVLFGFWFGSVSTSTGTTSGSTFLIQSTNAIAKGVQSTFTTSANLGTEGSKDGEVYQSPIFDATVKQTFNFVNSGSLDGKMENGKKLDESKLLEKPKLSKKEKAKFEDERSTYIKNNEKDNPYFAQDGAKTMEKAFGVGVGVVNLAVLAVPVTYINIMLNVIQIIVDLLILVFPIIALVSFFPRCQMMMFKFFKSLIGILFLPVVFGIFLSVLFWVNKLIDQTFLGLMDKVSSSLLMVMSGGVFLLGTLIVTALVKIILYRKIWKSRYKILSFFSDGQVQQPSFESKMNEKTKETVERTGEIGVGAVKAGIGASTGNLALAADGASHLMPKHDKALNLAKDHFIDDNGQFAGVKTGLNSLLNRSTQEEQQPFKDDMLPEEEIAEVEEPTNVDNEELEEIEDKALTDEVDNFEDSTDDEMDNSLEEFDVPVLDENVSDFDTDTSLADENNIELEPIIENELDSLDSSVESSENDREEPIQELDEQEIADNLNVRVDNFDELAFAREERAFFDGGEDSELITNNNDSLNNIYSFYQTEENFNNLEQTEEQFFGSVNTEEYNFDVVEG
>NZ_CP029612.1|WP_002393064.1|2691794_2692823_-|CHAP-domain-containing-protein
MKNLNKILIASCFVFILPFLLFLGVFSSSESGDSSQFQPATPQEKVALEVSNYVTSHGGTLQFAAAWIGNMEHESGLNPARIQSDLAFNPSIAYNASLGGYGIGLGQWDSGRRVNLLNFAKSQKKEWKSVALQMDFAWNKDGSDSDLLKRMSKSKDVNTLAVDILKLWERAGTKDDPVEQVKRKTSANNWYKRLSTGSMGGGSANIGGGEIDILENVLGQTINGGQCYGLSAFFVEKQGGFQMMGTGHMFASEIGNDYNWPSIGWKVIKNPNYSDIKAGDVINFGQGGVATSIYGHTGVVAGVEGKGKFTTYEQNAEQGQIVAKYSRTWGLDFPHVTSIVRK
>NZ_CP029612.1|WP_002393069.1|2704846_2705458_-|hypothetical-protein
MSREVIERNTKVAIAITEKMKKGRNDLKKAKEKIIQLDKQGELTIPFLKTTFEKLSESNEELLKEISRYDYTYVVHEAEMTVKEKAIWEEFFNIKKFYDKELSEFASFKEKYKYFEPKNSEELKKQARLLLEKKGYIVDSPFEGDFERWIGVYARPKDKPTYLDPTDGEEAGLQELYSVDGFKQDFAEWFEGEIVEGKLINMV
>NZ_CP029612.1|WP_002393070.1|2705535_2706819_-|XRE-family-transcriptional-regulator
MRGVDLKRYRKELKLKQIEMCQLLSITKGFYSNLESGKRPITQEMEKKIVEVLHIDGGHASVEAKIDFLRIRFKTLDVRTVIEKLLHMDMNWFTHESRGFYHYTETFSYSSIRIFRNPENVNMGIMLDLSGEGCRQLEEIFEEDNNRSWTEFFRSLYDDDIFGQGILVDTKITRIDIALDELIVKGQENFDLYILKEKMEQGLVDTTFKNFDFSGGFAYENKKMVNKGLSLYFGSRQSPLYFNFYQKDYELARKESVSVEEAREKYEIKNRYEIRLSDEKAFLFVEYFLSSGESLDWLVKEIINQSLTVFDIEEGAKVYCKAWYDIVDKLEGLKLSVQGEKPSIEKTLRWLSNYLAPSLKMIKEIDNLLGTNELMERIDLAELKEKHEEIIEMVCVDAKDLLFTTNQNSSVRSYMEQEFDLEEAYPF
>NZ_CP029612.1|WP_002410060.1|2707139_2707547_-|hypothetical-protein
MFSFEEVILQLENKIALKTLKNWANKIERLTDKKFERKYAKNSKGYTYSFKVFSSNDVESFFKLIDLRSKNIPLDIAISDVFMSEEEKKKKETISITKAEFRENQATVKELIDLVKDVLSDNAEIKKRLKVLEMK
>NZ_CP029612.1|WP_002371426.1|2707556_2707844_-|hypothetical-protein
MKFKSQGQMLSYVKEKEQKIIKEIDRRAEKEGVLDNNRLLDYKSLVTSILDAEAFYDEDRPVEEKKFSTSQEVDKYLETIFKEHMDSAWKEIFGK
>NZ_CP029612.1|WP_002371427.1|2707833_2708112_-|hypothetical-protein
MDSNEIIKHVRERVYVEVKKRYKKPDLDTRIRDILYEQSESYAKLVRFSNGKRIKKLTDPVEFEKFIENKGTKIVEEVIFALNKKEEKESEI
>NZ_CP029612.1|WP_002380872.1|2708130_2709639_-|cell-division-protein-FtsK
MVKKLFRYRGRRIRYSSRNLLALYRVLFFMPIFACLGYFVGYKWMYPLYLSNPTDWKIYIVPALIIMGVSIGSIVLITLLVKASIINSGYFSKVEQRQVLARMIIDNGYYTKKQVKGSDGKTKEKIKFPKIYYKSAKNSIFVSFETAGNKFQEKFETIGGFLETAFHADNLNKIDEKGFITYELASDVYNKRIWIKDMQADKGKVQLMKGLYWYFDKDPHLLLGGGTGGGKTFTILSLIYALCRVGEMEICDPKNSDLMALGKLPMFAGKVHTGKIDIVNCLKNAVELMNARFEMMNNSPDYKMGKNYAYYGLKPKFIVIDEFAAFKAELANDYAIDGDVDEYLTQLILKARQAGIFFIVAMQRPDGEFIKTALRDNFMFRMSVGRLSETGILMIFGDENKNKNFKYVEKVDGQKVYGRGYVAQGGSVAREFYSPQVPQDFDFIQEFIKISKELGYEEISKEVQEEVSKKISKHVDKEALAEIDEELEAGQAKLAKLSEKFG
>NZ_CP029612.1|WP_002371429.1|2709639_2710020_-|DUF86-domain-containing-protein
MRDSTAKDLRLLRGTLIYIEDIEQTLNRFGRDYETFYHDRVFFNAISMCLMQIGEYTVGNSGFSEEFKEKNSGKVDWKRLRNMRNMFAHSYSTMNERQIFRMATEYIPMYKEFCRQELARLKKEGR
>NZ_CP029612.1|WP_002393071.1|2710009_2710336_-|nucleotidyltransferase-domain-containing-protein
MVMTMNEIKERVKPVAEKHNVPVVYVFGSYARNEAKETSDIDFAVDITGQSEEAYWNLYGDFFEELKEAVAHDIDLVELETLVETQDKPERRELLATILKEGVKVFER
>NZ_CP029612.1|WP_002394269.1|2710395_2710689_-|hypothetical-protein
MGVKQEKYRRFLERKIRVYRMWQSFSYYSTLYLKLYNETSEYLIQFLLLDDLFFECDEAILNLLDNFLEQLVKAYNNKLHEDFDKGVFFEEYTSKVN
>NZ_CP029612.1|WP_002371434.1|2711109_2711298_+|hypothetical-protein
MLKTIEKACEIDMQSVTIILANNQRLKIEKFQSIIDDKILEFISSNIQYYIPEKSILYFTTS

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP029612_1	1.2\|1901785\|30\|NZ_CP029612\|CRISPRCasFinder,PILER-CR	1901785-1901814	30	NZ_CP029612.1	868846-868875	0	1.0

1. spacer 1.2|1901785|30|NZ_CP029612|CRISPRCasFinder,PILER-CR matches to position: 868846-868875, mismatch: 0, identity: 1.0

aacgtttttagggatccaaatacctttaaa	CRISPR spacer
aacgtttttagggatccaaatacctttaaa	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP029612_1	1.1\|1901719\|30\|NZ_CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	48974-49003	2	0.933
NZ_CP029612_1	1.1\|1901719\|30\|NZ_CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP042215	Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence	5329-5358	2	0.933
NZ_CP029612_1	1.1\|1901719\|30\|NZ_CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP015884	Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence	37424-37453	2	0.933
NZ_CP029612_1	1.1\|1901719\|30\|NZ_CP029612\|CRISPRCasFinder	1901719-1901748	30	NZ_CP046125	Enterococcus casseliflavus strain EC291 plasmid unnamed2, complete sequence	26283-26312	2	0.933
NZ_CP029612_3	3.1\|2703918\|29\|NZ_CP029612\|CRISPRCasFinder	2703918-2703946	29	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	652952-652980	7	0.759
NZ_CP029612_1	1.1\|1901719\|30\|NZ_CP029612\|CRISPRCasFinder	1901719-1901748	30	MN855818	Myoviridae sp. isolate 237, complete genome	9541-9570	8	0.733
NZ_CP029612_1	1.3\|1901851\|30\|NZ_CP029612\|CRISPRCasFinder,PILER-CR	1901851-1901880	30	NZ_CP049038	Pseudohalocynthiibacter aestuariivivens strain RR4-35 plasmid pRR4-35_1, complete sequence	145993-146022	8	0.733

1. spacer 1.1|1901719|30|NZ_CP029612|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
aattccgagtgattcacttttagcctgttc	Protospacer
.***********************.*****

2. spacer 1.1|1901719|30|NZ_CP029612|CRISPRCasFinder matches to NZ_CP042215 (Enterococcus faecalis strain L15 plasmid pL15-A, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
aattccgagtgattcacttttagcctgttc	Protospacer
.***********************.*****

3. spacer 1.1|1901719|30|NZ_CP029612|CRISPRCasFinder matches to NZ_CP015884 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
gattccgagtgattcgcttttagcctgttc	Protospacer
***************.********.*****

4. spacer 1.1|1901719|30|NZ_CP029612|CRISPRCasFinder matches to NZ_CP046125 (Enterococcus casseliflavus strain EC291 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.933

gattccgagtgattcacttttagcttgttc	CRISPR spacer
gattcctagtgattcacttttagcctgttc	Protospacer
****** *****************.*****

5. spacer 3.1|2703918|29|NZ_CP029612|CRISPRCasFinder matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 7, identity: 0.759

taggtgtt------ggttctggcgttggacccgga	CRISPR spacer
------ttccgcaaggttctggcgctggacccgga	Protospacer
      **      **********.**********

6. spacer 1.1|1901719|30|NZ_CP029612|CRISPRCasFinder matches to MN855818 (Myoviridae sp. isolate 237, complete genome) position: , mismatch: 8, identity: 0.733

gattccgagtgattcacttttagcttgttc	CRISPR spacer
aggtccgagtaaatcacttttagctttagc	Protospacer
.. *******.* *************   *

7. spacer 1.3|1901851|30|NZ_CP029612|CRISPRCasFinder,PILER-CR matches to NZ_CP049038 (Pseudohalocynthiibacter aestuariivivens strain RR4-35 plasmid pRR4-35_1, complete sequence) position: , mismatch: 8, identity: 0.733

agagacagcgggaaaactacgatattcatc	CRISPR spacer
aagcagttcgggaaaaccacgatattcatt	Protospacer
*.. *   *********.***********.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

413895 : 450492

Streptococcus_phage(40.0%)

transposase,integrase

attL 415485:415503|attR 450829:450847

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355365.1\|413895_415065_-\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	3.6e-31	28.9
WP_002355366.1\|415108_415339_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
415485:415503	attL	NA	NA	NA	NA
WP_002364925.1\|416437_416839_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_110115306.1\|418791_419954_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.7e-79	50.9
WP_002364921.1\|420061_420916_+	ParA family protein	A0A1X9I765	Streptococcus_phage	5.0e-152	97.9
WP_002355411.1\|420986_421202_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	2.1e-30	95.7
WP_002326825.1\|421218_421491_+	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.4e-07	96.7
WP_002355414.1\|421492_421801_+	zeta toxin	NA	NA	NA	NA
WP_071623404.1\|421880_422309_-\|integrase	tyrosine-type recombinase/integrase	W6LMU7	Streptococcus_phage	5.8e-16	35.7
WP_002355415.1\|422353_422854_-	HAD family hydrolase	NA	NA	NA	NA
WP_002355416.1\|422858_423626_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002355418.1\|424113_424539_+	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
WP_002345825.1\|424555_425071_+	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_002363040.1\|425081_426014_+	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_002355420.1\|426016_426997_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_002290550.1\|427024_427342_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_002343085.1\|427341_429048_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_002290548.1\|429194_430601_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
WP_002355422.1\|430623_430896_+	DUF3884 family protein	NA	NA	NA	NA
WP_002355424.1\|430916_431816_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_002363043.1\|432252_432861_+	zeta-toxin	NA	NA	NA	NA
WP_002384822.1\|432808_433087_-	recombinase family protein	NA	NA	NA	NA
WP_002363045.1\|433074_433395_-	recombinase family protein	A0A219Y912	Aeromonas_phage	5.5e-19	45.1
WP_002355428.1\|437013_437988_+	choloylglycine hydrolase family protein	M1H001	Paramecium_bursaria_Chlorella_virus	2.1e-24	31.6
WP_002364917.1\|438432_438738_+	hypothetical protein	NA	NA	NA	NA
WP_002363048.1\|438731_439259_+	hypothetical protein	NA	NA	NA	NA
WP_002380048.1\|439510_439693_+	hypothetical protein	NA	NA	NA	NA
WP_000221326.1\|440307_441267_-\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002363055.1\|441390_441663_-	hypothetical protein	NA	NA	NA	NA
WP_002363054.1\|442004_442214_-	hypothetical protein	NA	NA	NA	NA
WP_002363053.1\|442273_442498_-	hypothetical protein	NA	NA	NA	NA
WP_002363052.1\|442491_442779_-	hypothetical protein	NA	NA	NA	NA
WP_002363051.1\|442795_443392_-	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	2.2e-21	38.1
WP_002363050.1\|443529_444372_-	hypothetical protein	NA	NA	NA	NA
WP_110115307.1\|444676_445636_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002363056.1\|446036_446444_+	hypothetical protein	NA	NA	NA	NA
WP_002380049.1\|446521_447403_+	peptidase S41	NA	NA	NA	NA
WP_002384831.1\|447573_448239_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002358517.1\|448255_448447_+	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002358518.1\|448475_449012_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_000195429.1\|449319_450492_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
450829:450847	attR	NA	NA	NA	NA

DBSCAN-SWA_2

839307 : 881458

Enterococcus_phage(40.74%)

transposase,head,portal,terminase,integrase,tRNA

attL 849994:850009|attR 874158:874173

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002387984.1\|839307_842088_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	8.6e-92	27.8
WP_002363411.1\|842139_843663_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	3.6e-76	33.7
WP_002355907.1\|843662_844331_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_002355908.1\|844502_844871_-	DUF4828 domain-containing protein	NA	NA	NA	NA
WP_002363412.1\|845069_845801_+	DNA/RNA nuclease SfsA	NA	NA	NA	NA
WP_002355910.1\|845906_846905_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002355911.1\|846931_848233_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.6e-40	32.6
WP_002355912.1\|848277_850983_+	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
849994:850009	attL	NA	NA	NA	NA
WP_002355913.1\|851211_851529_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002355915.1\|853181_853400_+	hypothetical protein	NA	NA	NA	NA
WP_002355916.1\|853413_853614_+	DUF3188 domain-containing protein	NA	NA	NA	NA
WP_095714962.1\|853613_854024_+	DUF3284 domain-containing protein	NA	NA	NA	NA
WP_002355918.1\|854299_854626_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002355919.1\|854648_854969_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_002355920.1\|855034_856312_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002355921.1\|856395_857790_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_162565045.1\|857829_859041_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_010712197.1\|859505_860642_-\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	5.4e-93	46.5
WP_010712198.1\|860717_861047_-	hypothetical protein	NA	NA	NA	NA
WP_095714960.1\|861060_861795_-	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	3.2e-22	51.0
WP_064687096.1\|861816_862455_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_010716881.1\|862469_862811_-	helix-turn-helix transcriptional regulator	A0A141DZM2	Streptococcus_phage	7.2e-17	44.7
WP_002364354.1\|863131_863308_+	helix-turn-helix transcriptional regulator	D2IZW2	Enterococcus_phage	1.7e-14	65.5
WP_095714959.1\|863321_863660_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_095714958.1\|863717_863999_+	hypothetical protein	NA	NA	NA	NA
WP_095714957.1\|864398_865109_+	phage regulatory protein	D2IYT0	Enterococcus_phage	1.2e-122	95.7
WP_033598023.1\|865119_865305_+	hypothetical protein	D2IZW5	Enterococcus_phage	1.4e-19	88.3
WP_095714956.1\|865297_865516_+	hypothetical protein	D2J031	Enterococcus_phage	2.1e-09	49.2
WP_162565037.1\|865527_865668_+	hypothetical protein	NA	NA	NA	NA
WP_025188165.1\|865832_866018_-	DUF1508 domain-containing protein	NA	NA	NA	NA
WP_002404544.1\|866183_866486_+	hypothetical protein	NA	NA	NA	NA
WP_002381628.1\|866676_867156_+	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	1.2e-33	48.4
WP_095714955.1\|867167_868184_+	AAA family ATPase	A0A0S2SY47	Bacillus_phage	9.2e-60	43.2
WP_095714954.1\|868188_868830_+	hypothetical protein	U5U4M2	Lactobacillus_phage	9.7e-31	36.0
WP_095714953.1\|868833_869631_+	helix-turn-helix domain-containing protein	A0A2D1GQ66	Lysinibacillus_phage	2.7e-22	54.4
WP_057086515.1\|869635_870163_+	single-stranded DNA-binding protein	A0A097PAQ3	Streptococcus_pyogenes_phage	4.5e-42	54.9
WP_033600926.1\|870175_870505_+	hypothetical protein	NA	NA	NA	NA
WP_095714952.1\|870524_870731_+	hypothetical protein	A0A1B1V001	Enterococcus_phage	2.8e-24	96.8
WP_002406058.1\|870783_871437_+	SAM-dependent DNA methyltransferase	A0A2D1GPI7	Lactobacillus_phage	1.4e-61	54.0
WP_002406057.1\|871433_872378_+\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.8e-102	59.3
WP_095715049.1\|872390_872963_+	hypothetical protein	A8ATD7	Listeria_phage	1.3e-23	33.1
WP_095715052.1\|872946_873333_+	hypothetical protein	D2IZL0	Enterococcus_phage	3.3e-18	43.9
WP_063855928.1\|873329_873668_+	hypothetical protein	S6CQM6	Streptococcus_phage	2.5e-14	44.1
WP_002373022.1\|873667_873907_+	hypothetical protein	NA	NA	NA	NA
WP_010825832.1\|873906_874155_+	hypothetical protein	NA	NA	NA	NA
WP_095715050.1\|874166_874700_+	DUF1642 domain-containing protein	D2IZZ0	Enterococcus_phage	5.8e-13	33.0
874158:874173	attR	NA	NA	NA	NA
WP_105577456.1\|874861_875074_+	hypothetical protein	D2IZL5	Enterococcus_phage	4.3e-28	87.7
WP_002395898.1\|875074_875494_+	transcriptional regulator	NA	NA	NA	NA
WP_095715045.1\|875741_876386_+	hypothetical protein	NA	NA	NA	NA
WP_095715044.1\|876452_876914_+\|transposase	transposase	D2IZL8	Enterococcus_phage	8.7e-58	74.8
WP_095715043.1\|876906_878295_+\|terminase	phage terminase large subunit	Q9AZ66	Lactococcus_phage	5.3e-175	67.0
WP_095715042.1\|878307_879783_+\|portal	phage portal protein	A0A0A7AQF2	Bacillus_phage	1.7e-30	25.8
WP_095715041.1\|879757_880798_+\|head	phage head morphogenesis protein	NA	NA	NA	NA
WP_095715040.1\|880806_881127_+	hypothetical protein	NA	NA	NA	NA
WP_025189865.1\|881194_881458_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	2.9e-42	95.4

DBSCAN-SWA_3

884896 : 916034

Lactococcus_phage(27.27%)

transposase,tail,plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095715035.1\|884896_885739_+\|tail	phage tail protein	A5GYM0	Lactococcus_phage	5.5e-10	53.9
WP_095715034.1\|885792_886143_+	hypothetical protein	A0A2H4JAA8	uncultured_Caudovirales_phage	4.1e-07	37.0
WP_162565058.1\|886391_889310_+	tape measure protein	D7RWD8	Brochothrix_phage	3.1e-76	42.8
WP_095715032.1\|889299_890034_+\|tail	phage tail protein	B8R658	Lactobacillus_phage	4.5e-16	31.9
WP_162565046.1\|890015_892730_+	peptidoglycan DD-metalloendopeptidase family protein	Q9AZX5	Lactococcus_phage	1.9e-176	38.2
WP_095715030.1\|892744_893653_+\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	1.4e-11	26.7
WP_002383821.1\|893645_893963_+	hypothetical protein	NA	NA	NA	NA
WP_002383822.1\|893955_894273_+	hypothetical protein	NA	NA	NA	NA
WP_010821095.1\|894272_894824_+	hypothetical protein	NA	NA	NA	NA
WP_095715055.1\|894838_895213_+	hypothetical protein	NA	NA	NA	NA
WP_002380794.1\|895212_895350_+	XkdX family protein	NA	NA	NA	NA
WP_002367247.1\|895384_895618_+\|holin	holin	D2J075	Enterococcus_phage	7.0e-24	70.2
WP_010711247.1\|895620_895824_+\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	98.5
WP_095715054.1\|895828_896914_+	N-acetylmuramoyl-L-alanine amidase	A0A1D3SNQ1	Enterococcus_phage	1.1e-87	50.7
WP_002402066.1\|897308_897842_+	hypothetical protein	NA	NA	NA	NA
WP_095715047.1\|898060_898546_+	hypothetical protein	NA	NA	NA	NA
WP_002355924.1\|898712_899045_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_002363418.1\|899158_901804_-	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	3.3e-85	39.9
WP_002383424.1\|901916_902603_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002355927.1\|902615_903428_+	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_002358907.1\|903498_906030_-	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
WP_002358908.1\|906026_906761_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_002363420.1\|906937_907522_+	hypothetical protein	NA	NA	NA	NA
WP_002393455.1\|907544_908600_+	endonuclease subunit UvrC	NA	NA	NA	NA
WP_010774547.1\|908648_910886_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.1e-120	30.9
WP_162565047.1\|911047_913336_+	6-aminohexanoate hydrolase	NA	NA	NA	NA
WP_002393453.1\|913412_914357_+	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
WP_002363425.1\|914399_915053_+	DUF4767 domain-containing protein	NA	NA	NA	NA
WP_000221326.1\|915074_916034_-\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

987452 : 1020890

Enterococcus_phage(25.81%)

capsid,portal,terminase,tail,protease,holin,integrase

attL 986036:986051|attR 992782:992797

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
986036:986051	attL	NA	NA	NA	NA
WP_025193885.1\|987452_988583_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	2.7e-100	50.4
WP_016633414.1\|988666_989572_-	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_016633415.1\|989665_990088_-	hypothetical protein	NA	NA	NA	NA
WP_010708602.1\|990088_990430_-	helix-turn-helix transcriptional regulator	A0A141DZM2	Streptococcus_phage	2.8e-21	46.7
WP_002371609.1\|990719_990911_+	hypothetical protein	NA	NA	NA	NA
WP_002358109.1\|990923_991253_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_002358108.1\|991260_991449_+	hypothetical protein	A0A0S2MY96	Enterococcus_phage	2.7e-18	80.7
WP_016633416.1\|991515_991815_+	hypothetical protein	NA	NA	NA	NA
WP_002358104.1\|991811_992036_+	hypothetical protein	D2IZX4	Enterococcus_phage	2.2e-22	69.9
WP_010774955.1\|992038_992395_+	hypothetical protein	NA	NA	NA	NA
WP_016633417.1\|992485_993451_+	recombinase RecT	A0A1X9I5N6	Streptococcus_phage	1.2e-77	62.6
992782:992797	attR	NA	NA	NA	NA
WP_016633418.1\|993413_994229_+	hypothetical protein	J7KGZ1	Streptococcus_phage	3.0e-61	50.6
WP_002402868.1\|994243_995023_+	DnaD domain protein	B4XYS6	Lactobacillus_phage	2.3e-42	63.4
WP_016633419.1\|995034_995874_+	ATP-binding protein	U5PVD6	Bacillus_phage	4.5e-20	32.1
WP_002402870.1\|996011_996281_+	hypothetical protein	NA	NA	NA	NA
WP_025193886.1\|996429_996894_+	DUF1064 domain-containing protein	A0A1I9KKZ1	Lactobacillus_phage	1.7e-32	48.3
WP_016633421.1\|996913_997519_+	hypothetical protein	NA	NA	NA	NA
WP_016633422.1\|997534_997741_+	hypothetical protein	A0A1B1V001	Enterococcus_phage	1.3e-24	96.8
WP_002373959.1\|998403_998871_+	ArpU family transcriptional regulator	D7RWH7	Brochothrix_phage	2.9e-08	27.8
WP_016633423.1\|999177_999684_-	hypothetical protein	NA	NA	NA	NA
WP_016633424.1\|1000211_1000481_+	hypothetical protein	NA	NA	NA	NA
WP_016633425.1\|1000541_1000856_+	hypothetical protein	NA	NA	NA	NA
WP_016633426.1\|1000848_1001160_+	HNH endonuclease	A0A1S5SFB3	Streptococcus_phage	4.0e-30	64.1
WP_154591510.1\|1001164_1001308_+	hypothetical protein	NA	NA	NA	NA
WP_033601507.1\|1001443_1001752_+\|terminase	terminase	D2XR14	Bacillus_phage	3.2e-16	50.0
WP_016630714.1\|1001748_1003431_+\|terminase	terminase large subunit	D2XR15	Bacillus_phage	8.0e-226	69.4
WP_002400743.1\|1003464_1003632_-	YjzC family protein	A0A0A7RTS6	Clostridium_phage	4.0e-13	74.0
WP_016630713.1\|1003919_1004102_+	hypothetical protein	NA	NA	NA	NA
WP_002396873.1\|1004134_1005298_+\|portal	phage portal protein	A0A059T6F0	Listeria_phage	1.8e-75	39.5
WP_016633428.1\|1005284_1006004_+\|protease	Clp protease ClpP	A0A2H4J8Y7	uncultured_Caudovirales_phage	2.7e-42	45.0
WP_016633429.1\|1006000_1007188_+\|capsid	phage major capsid protein	D2XR18	Bacillus_phage	7.2e-64	37.1
WP_002380686.1\|1007264_1007546_+	hypothetical protein	A0A2H4JAM0	uncultured_Caudovirales_phage	1.8e-13	48.8
WP_016633430.1\|1007520_1007907_+	hypothetical protein	A8ATA1	Listeria_phage	3.8e-30	54.3
WP_016633431.1\|1007903_1008308_+	phage protein, HK97 gp10 family	A0A2P0ZLD7	Lactobacillus_phage	2.0e-18	42.6
WP_016633432.1\|1008304_1008700_+	hypothetical protein	A0A059T681	Listeria_phage	1.5e-18	46.3
WP_016633433.1\|1008732_1009326_+\|tail	phage major tail protein, phi13 family	A0A060AKE9	Staphylococcus_phage	2.6e-22	35.1
WP_016633434.1\|1009399_1009873_+	Ig domain-containing protein	A0A1D6Z291	Staphylococcus_phage	3.9e-21	45.6
WP_016633435.1\|1009929_1010277_+	hypothetical protein	NA	NA	NA	NA
WP_010820079.1\|1010498_1015250_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.6e-13	42.2
WP_002371567.1\|1015249_1016149_+\|tail	phage tail family protein	D2J071	Enterococcus_phage	2.9e-49	37.4
WP_002371566.1\|1016151_1017276_+	hypothetical protein	Q77MU2	Lactococcus_phage	2.6e-87	45.0
WP_016633436.1\|1017286_1018342_+	hypothetical protein	D2J073	Enterococcus_phage	9.0e-50	37.0
WP_002381464.1\|1018353_1019142_+	hypothetical protein	D2IYX9	Enterococcus_phage	3.3e-41	71.6
WP_002358058.1\|1019177_1019576_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	1.6e-36	54.2
WP_095714931.1\|1019630_1020890_+	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	6.6e-225	91.6

DBSCAN-SWA_5

1199404 : 1217175

Enterococcus_phage(46.15%)

tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002380203.1\|1199404_1201801_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.3e-19	24.2
WP_002360497.1\|1201825_1202176_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002393873.1\|1202258_1202489_+	hypothetical protein	NA	NA	NA	NA
WP_002382232.1\|1202548_1203034_-	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_002360496.1\|1203068_1203551_-	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	2.6e-20	47.7
WP_002393201.1\|1203947_1204703_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	8.7e-31	56.0
WP_002380205.1\|1204721_1205564_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.3e-30	30.7
WP_002363798.1\|1205630_1206023_+	hypothetical protein	NA	NA	NA	NA
WP_002360491.1\|1206042_1206450_+	RinA family phage transcriptional activator	NA	NA	NA	NA
WP_002382237.1\|1206670_1207087_+	hypothetical protein	NA	NA	NA	NA
WP_002380206.1\|1207099_1207612_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
WP_002357848.1\|1207644_1208004_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_002382238.1\|1208096_1208390_+	hypothetical protein	NA	NA	NA	NA
WP_002393202.1\|1208379_1211313_+	membrane protein	A0A1U9WR55	Streptococcus_virus	1.1e-09	25.0
WP_002365553.1\|1211314_1212241_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	9.0e-147	78.6
WP_002380208.1\|1212253_1213711_+	hypothetical protein	C9E2K6	Enterococcus_phage	4.7e-174	47.5
WP_002380209.1\|1213743_1215513_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	1.7e-141	63.6
WP_002380211.1\|1215536_1215932_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	1.7e-33	48.9
WP_002393203.1\|1216050_1217175_+	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	5.4e-77	44.3

DBSCAN-SWA_6

1349112 : 1405451

Listeria_phage(48.0%)

capsid,plate,terminase,tail,integrase

attL 1349067:1349089|attR 1409156:1409178

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1349067:1349089	attL	NA	NA	NA	NA
WP_010774185.1\|1349112_1350339_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	6.5e-76	41.9
WP_095714987.1\|1350338_1350620_-	hypothetical protein	NA	NA	NA	NA
WP_095714988.1\|1350775_1351369_-	hypothetical protein	D2J022	Enterococcus_phage	8.1e-24	55.3
WP_095714989.1\|1351427_1352180_-	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	5.7e-06	35.6
WP_095714990.1\|1352197_1352662_-	ImmA/IrrE family metallo-endopeptidase	R4IBK9	Listeria_phage	1.5e-20	36.6
WP_002386707.1\|1352682_1353006_-	helix-turn-helix transcriptional regulator	A8ATJ9	Listeria_phage	2.3e-17	66.7
WP_095714991.1\|1353171_1353363_+	helix-turn-helix transcriptional regulator	A8ATK0	Listeria_phage	5.6e-11	58.3
WP_162565049.1\|1353369_1353549_+	hypothetical protein	NA	NA	NA	NA
WP_162565059.1\|1353617_1354172_+	hypothetical protein	NA	NA	NA	NA
WP_002386711.1\|1354221_1354383_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010774193.1\|1354562_1354778_+	hypothetical protein	NA	NA	NA	NA
WP_002392047.1\|1354833_1355124_+	hypothetical protein	NA	NA	NA	NA
WP_095714995.1\|1355128_1357243_+	AAA family ATPase	A0A1L2K2K3	Aeribacillus_phage	6.8e-49	25.4
WP_002392045.1\|1357243_1358416_+	hypothetical protein	NA	NA	NA	NA
WP_002390536.1\|1358415_1359117_+	MBL fold metallo-hydrolase	A0A1L2JY21	Aeribacillus_phage	6.0e-50	42.7
WP_095714996.1\|1359128_1359893_+	DnaD domain protein	A0A1B0Y2R2	Lactobacillus_phage	7.5e-14	61.4
WP_002386718.1\|1359908_1360406_+	recombinase RecU	A0A1L2JY30	Aeribacillus_phage	8.3e-14	35.4
WP_002386719.1\|1360426_1360741_+	hypothetical protein	NA	NA	NA	NA
WP_002392043.1\|1360824_1361574_+	hypothetical protein	D2IZY3	Enterococcus_phage	8.7e-116	84.5
WP_002386721.1\|1361598_1361793_+	hypothetical protein	NA	NA	NA	NA
WP_095714997.1\|1361823_1362051_+	hypothetical protein	C9E2N4	Enterococcus_phage	1.0e-06	50.9
WP_095714998.1\|1362109_1362850_+	DNA methyltransferase	U4KJA1	Streptococcus_phage	2.5e-99	69.0
WP_002406058.1\|1362906_1363560_+	SAM-dependent DNA methyltransferase	A0A2D1GPI7	Lactobacillus_phage	1.4e-61	54.0
WP_002406057.1\|1363556_1364501_+\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.8e-102	59.3
WP_095715049.1\|1364513_1365086_+	hypothetical protein	A8ATD7	Listeria_phage	1.3e-23	33.1
WP_095715052.1\|1365069_1365456_+	hypothetical protein	D2IZL0	Enterococcus_phage	3.3e-18	43.9
WP_063855928.1\|1365452_1365791_+	hypothetical protein	S6CQM6	Streptococcus_phage	2.5e-14	44.1
WP_002373022.1\|1365790_1366030_+	hypothetical protein	NA	NA	NA	NA
WP_010825832.1\|1366029_1366278_+	hypothetical protein	NA	NA	NA	NA
WP_095715050.1\|1366289_1366823_+	DUF1642 domain-containing protein	D2IZZ0	Enterococcus_phage	5.8e-13	33.0
WP_110115310.1\|1366984_1367197_+	hypothetical protein	D2IZL5	Enterococcus_phage	1.1e-28	87.9
WP_002386738.1\|1367288_1367477_+	hypothetical protein	NA	NA	NA	NA
WP_010774597.1\|1367577_1368162_+	positive control factor	NA	NA	NA	NA
WP_002425326.1\|1368868_1369171_+	hypothetical protein	NA	NA	NA	NA
WP_002392029.1\|1370350_1370581_+	hypothetical protein	A8ATN7	Listeria_phage	2.3e-11	52.3
WP_002392028.1\|1370595_1371321_+\|terminase	terminase small subunit	NA	NA	NA	NA
WP_085382889.1\|1371301_1372738_+\|terminase	phage terminase large subunit	A5GYP8	Lactococcus_phage	3.8e-200	72.4
WP_010714024.1\|1372760_1374155_+	DUF1073 domain-containing protein	A8ATG1	Listeria_phage	8.0e-147	56.4
WP_162565050.1\|1374117_1375389_+\|capsid	minor capsid protein	A8ATG2	Listeria_phage	2.1e-53	41.6
WP_002386748.1\|1375602_1375890_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.7e-27	68.3
WP_002386749.1\|1375882_1376092_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_010706625.1\|1376104_1377208_+	DUF2213 domain-containing protein	A8ATG4	Listeria_phage	1.7e-88	50.6
WP_002386751.1\|1377210_1377681_+	hypothetical protein	NA	NA	NA	NA
WP_010733792.1\|1377701_1378583_+	DUF2184 domain-containing protein	A8ATG6	Listeria_phage	6.7e-83	52.2
WP_095715021.1\|1378602_1378989_+	hypothetical protein	NA	NA	NA	NA
WP_002377536.1\|1379000_1379342_+	DUF4054 domain-containing protein	NA	NA	NA	NA
WP_162565051.1\|1379341_1379944_+	hypothetical protein	A8ATG9	Listeria_phage	3.9e-34	43.1
WP_095715019.1\|1379943_1380303_+	hypothetical protein	A0A2H4JDP3	uncultured_Caudovirales_phage	2.3e-13	43.7
WP_002392020.1\|1380289_1380766_+	hypothetical protein	A8ATH1	Listeria_phage	7.2e-23	42.8
WP_010708191.1\|1380762_1381800_+	DUF3383 family protein	A8ATH2	Listeria_phage	8.4e-101	56.4
WP_002377526.1\|1381815_1382214_+	hypothetical protein	A8ATH3	Listeria_phage	6.6e-30	54.0
WP_002400012.1\|1382266_1382599_+	hypothetical protein	A8ATH4	Listeria_phage	6.3e-26	57.8
WP_095715018.1\|1382782_1387966_+	peptidoglycan DD-metalloendopeptidase family protein	A8ATH6	Listeria_phage	4.7e-152	43.1
WP_002386767.1\|1387965_1388523_+	LysM peptidoglycan-binding domain-containing protein	A8ATH7	Listeria_phage	2.8e-34	43.2
WP_002390591.1\|1388532_1388895_+	hypothetical protein	A8ATH8	Listeria_phage	1.1e-28	45.8
WP_002390593.1\|1388895_1389726_+	hypothetical protein	A8ATH9	Listeria_phage	7.8e-65	45.8
WP_002377515.1\|1389725_1390058_+	hypothetical protein	A8ATI0	Listeria_phage	1.6e-21	50.0
WP_002390594.1\|1390057_1390405_+	DUF2634 domain-containing protein	A0A2H4J4S8	uncultured_Caudovirales_phage	2.9e-13	49.4
WP_002386771.1\|1390397_1391552_+\|plate	baseplate J/gp47 family protein	A8ATI2	Listeria_phage	4.3e-114	54.1
WP_002392881.1\|1391535_1392165_+	hypothetical protein	A8ATI3	Listeria_phage	4.1e-58	57.4
WP_095715017.1\|1392177_1393653_+\|tail	tail fiber protein	D2J018	Enterococcus_phage	4.3e-58	61.3
WP_002386774.1\|1393687_1394122_+	hypothetical protein	NA	NA	NA	NA
WP_002392120.1\|1394121_1394250_+	XkdX family protein	NA	NA	NA	NA
WP_002377506.1\|1394254_1394611_+	hypothetical protein	NA	NA	NA	NA
WP_002392119.1\|1394607_1394805_+	hypothetical protein	NA	NA	NA	NA
WP_095715054.1\|1394862_1395948_+	N-acetylmuramoyl-L-alanine amidase	A0A1D3SNQ1	Enterococcus_phage	1.1e-87	50.7
WP_002402066.1\|1396342_1396876_+	hypothetical protein	NA	NA	NA	NA
WP_095714874.1\|1397015_1397264_-	hypothetical protein	A0A097BYB1	Enterococcus_phage	1.2e-34	91.5
WP_010774185.1\|1397674_1398901_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	6.5e-76	41.9
WP_095714987.1\|1398900_1399182_-	hypothetical protein	NA	NA	NA	NA
WP_095714988.1\|1399337_1399931_-	hypothetical protein	D2J022	Enterococcus_phage	8.1e-24	55.3
WP_002390594.1\|1401855_1402203_+	DUF2634 domain-containing protein	A0A2H4J4S8	uncultured_Caudovirales_phage	2.9e-13	49.4
WP_002386771.1\|1402195_1403350_+\|plate	baseplate J/gp47 family protein	A8ATI2	Listeria_phage	4.3e-114	54.1
WP_002392881.1\|1403333_1403963_+	hypothetical protein	A8ATI3	Listeria_phage	4.1e-58	57.4
WP_095715017.1\|1403975_1405451_+\|tail	tail fiber protein	D2J018	Enterococcus_phage	4.3e-58	61.3
1409156:1409178	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1695822 : 1704466

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002357276.1\|1695822_1696395_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.1e-25	35.1
WP_002380373.1\|1696391_1697423_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	1.1e-55	44.4
WP_002393350.1\|1697424_1698864_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.7e-49	32.1
WP_002380375.1\|1698839_1701059_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.8e-146	39.8
WP_002361952.1\|1701055_1701730_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|1701730_1701982_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002357270.1\|1701995_1702709_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	4.3e-48	43.0
WP_002380376.1\|1702860_1703985_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002360132.1\|1703977_1704466_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.8e-19	42.0

DBSCAN-SWA_8

1735454 : 1761022

Clostridium_botulinum_C_phage(20.0%)

transposase,protease,integrase

attL 1759220:1759244|attR 1764286:1764310

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002393340.1\|1735454_1736333_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_095714856.1\|1736387_1737890_-	M4 family metallopeptidase coccolysin	NA	NA	NA	NA
WP_002393338.1\|1738124_1739468_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_002377181.1\|1739464_1740193_-	accessory gene regulator AgrB	NA	NA	NA	NA
WP_002357224.1\|1740281_1741025_-	response regulator transcription factor	NA	NA	NA	NA
WP_002380394.1\|1741431_1743414_-	amidase domain-containing protein	Q332B8	Clostridium_botulinum_C_phage	3.1e-19	36.8
WP_002369238.1\|1745852_1746605_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002393335.1\|1746940_1747933_-	DUF4767 domain-containing protein	NA	NA	NA	NA
WP_002385850.1\|1748023_1748602_-	HD domain-containing protein	NA	NA	NA	NA
WP_002369233.1\|1748825_1749731_+	polysaccharide deacetylase	NA	NA	NA	NA
WP_002297659.1\|1749997_1751176_-\|integrase	site-specific integrase	S6C485	Thermus_phage	3.4e-29	30.5
WP_002382441.1\|1751278_1751635_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002360096.1\|1751938_1752184_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002297668.1\|1752177_1752579_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_095714855.1\|1753146_1754982_-	beta-galactosidase	NA	NA	NA	NA
WP_002330923.1\|1755153_1756416_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_095714854.1\|1756553_1756940_+	hypothetical protein	NA	NA	NA	NA
WP_002298157.1\|1757033_1758326_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.9e-31	40.4
WP_002313174.1\|1758599_1758860_-	hypothetical protein	NA	NA	NA	NA
1759220:1759244	attL	NA	NA	NA	NA
WP_110115311.1\|1759464_1760626_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.0e-79	51.3
WP_077497620.1\|1760698_1760905_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	2.0e-06	53.3
WP_002383094.1\|1760908_1761022_+\|transposase	IS3 family transposase	NA	NA	NA	NA
1764286:1764310	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1777030 : 1788514

Streptococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002298830.1\|1777030_1778035_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	1.4e-121	66.3
WP_002384404.1\|1778031_1780155_-\|transposase	transposase	A0A1S5SF30	Streptococcus_phage	2.4e-174	58.7
WP_002330910.1\|1780159_1782607_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.4
WP_002298826.1\|1782593_1782983_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	2.5e-42	66.7
WP_002383098.1\|1783034_1783775_+	hypothetical protein	NA	NA	NA	NA
WP_002360078.1\|1783781_1784618_-	abortive infection family protein	NA	NA	NA	NA
WP_002298823.1\|1784682_1785186_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	3.1e-56	61.2
WP_002298822.1\|1785198_1785420_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.5e-28	87.7
WP_002346915.1\|1785816_1787067_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.1e-114	62.1
WP_002330905.1\|1787198_1787333_-	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_002360076.1\|1787329_1788514_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	1.0e-142	62.1

DBSCAN-SWA_10

1919916 : 1938246

Enterococcus_phage(44.44%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002380455.1\|1919916_1920987_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-29	35.1
WP_002359996.1\|1922425_1922674_+	hypothetical protein	A0A097BYB1	Enterococcus_phage	6.1e-34	91.5
WP_002399566.1\|1922692_1923691_-	Abi family protein	A0A059NT88	Lactococcus_phage	1.0e-79	43.5
WP_002399567.1\|1924471_1925473_-	endolysin	F0PIJ7	Enterococcus_phage	1.9e-86	68.4
WP_002359993.1\|1925444_1925723_-\|holin	holin	NA	NA	NA	NA
WP_002359992.1\|1925722_1925977_-	hypothetical protein	NA	NA	NA	NA
WP_002359991.1\|1925989_1926409_-	XkdX family protein	F0PIJ5	Enterococcus_phage	1.1e-56	85.4
WP_002399568.1\|1926396_1927257_-	collagen-like protein	F0PIJ4	Enterococcus_phage	1.2e-60	87.3
WP_002359989.1\|1927243_1927732_-	hypothetical protein	A0A1W6JI16	Lactococcus_phage	8.4e-35	46.0
WP_002359987.1\|1927744_1928437_-	hypothetical protein	NA	NA	NA	NA
WP_002359986.1\|1928433_1931010_-	endolysin	A0A1B1IM47	Lactococcus_phage	1.3e-30	46.6
WP_002393633.1\|1931046_1931958_-	hypothetical protein	NA	NA	NA	NA
WP_002393634.1\|1931963_1933079_-	hypothetical protein	NA	NA	NA	NA
WP_095714915.1\|1933083_1938246_-	tape measure protein	A0A1P8VVL4	Streptococcus_phage	1.2e-35	30.1

DBSCAN-SWA_11

1949280 : 1962685

Enterococcus_phage(68.75%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002415447.1\|1949280_1949700_-	hypothetical protein	A0A2H4J1L3	uncultured_Caudovirales_phage	4.7e-18	51.0
WP_010708137.1\|1949689_1950886_-	ParB N-terminal domain-containing protein	Q708N6	Streptococcus_phage	1.8e-110	51.1
WP_002393643.1\|1951293_1951719_-	ArpU family transcriptional regulator	D2IYV6	Enterococcus_phage	9.9e-24	42.3
WP_002380480.1\|1952017_1952218_-	hypothetical protein	D2IYV2	Enterococcus_phage	2.9e-26	84.8
WP_095714913.1\|1952218_1952785_-	DUF1642 domain-containing protein	D2IZL3	Enterococcus_phage	2.0e-40	49.0
WP_010822330.1\|1952777_1952945_-	hypothetical protein	A0A097BY78	Enterococcus_phage	8.9e-21	94.5
WP_095714912.1\|1952941_1953301_-	DNA topoisomerase	NA	NA	NA	NA
WP_095714911.1\|1953297_1953732_-	hypothetical protein	A0A097BY34	Enterococcus_phage	7.2e-30	55.0
WP_033626304.1\|1953986_1954784_-	DNA adenine methylase	R4IBV6	Listeria_phage	2.2e-109	69.8
WP_162565053.1\|1955088_1955448_-	hypothetical protein	A0A2L0V129	Agrobacterium_phage	1.1e-12	41.6
WP_033782220.1\|1955450_1955783_-	hypothetical protein	A0A0S2MYB8	Enterococcus_phage	1.9e-22	59.7
WP_095714909.1\|1955779_1956205_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	1.5e-59	82.6
WP_002368215.1\|1956222_1956522_-	hypothetical protein	D2IZY1	Enterococcus_phage	6.0e-44	91.9
WP_095714908.1\|1956521_1957514_-	DUF4373 domain-containing protein	D2IYU0	Enterococcus_phage	2.4e-145	91.8
WP_002380492.1\|1957527_1958421_-	hypothetical protein	D2IYT9	Enterococcus_phage	1.1e-149	91.2
WP_095714907.1\|1958554_1959496_-	endonuclease	D2IZK1	Enterococcus_phage	4.0e-134	73.9
WP_002380494.1\|1959509_1959821_-	hypothetical protein	NA	NA	NA	NA
WP_002359950.1\|1959851_1960142_-	hypothetical protein	NA	NA	NA	NA
WP_033782235.1\|1960226_1960553_-	hypothetical protein	NA	NA	NA	NA
WP_033782238.1\|1960553_1960763_-	hypothetical protein	NA	NA	NA	NA
WP_002393142.1\|1960905_1961139_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_095714906.1\|1961171_1961699_-	hypothetical protein	NA	NA	NA	NA
WP_048947967.1\|1961970_1962156_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_095714905.1\|1962307_1962685_+	helix-turn-helix transcriptional regulator	A0A2P1JU09	Anoxybacillus_phage	5.9e-12	35.4

DBSCAN-SWA_12

2249131 : 2334915

Enterococcus_phage(34.69%)

capsid,plate,transposase,portal,terminase,tail,integrase,tRNA

attL 2289162:2289183|attR 2331991:2332012

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095714923.1\|2249131_2249887_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_002380610.1\|2249966_2252009_-	penicillin-binding protein	NA	NA	NA	NA
WP_002356656.1\|2252216_2253449_+	virion core protein	NA	NA	NA	NA
WP_002380612.1\|2253552_2254698_+	hypothetical protein	NA	NA	NA	NA
WP_002392975.1\|2254694_2255504_+	TPM domain-containing protein	NA	NA	NA	NA
WP_002392974.1\|2255708_2256470_+	DUF3862 domain-containing protein	A9D9J1	Lactobacillus_prophage	1.6e-19	39.9
WP_002380615.1\|2256830_2257562_-	HAD family hydrolase	NA	NA	NA	NA
WP_002362220.1\|2257709_2257937_-	hypothetical protein	NA	NA	NA	NA
WP_002380616.1\|2258024_2258675_-	diphthine--ammonia ligase	NA	NA	NA	NA
WP_002380617.1\|2259337_2260150_-	ABC transporter permease	NA	NA	NA	NA
WP_002392972.1\|2260149_2261535_-	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_002359687.1\|2261518_2262658_-	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	3.5e-140	64.7
WP_002387128.1\|2262716_2263115_-	lipoprotein CpsH	NA	NA	NA	NA
WP_002359685.1\|2263132_2265586_-	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_002392969.1\|2265654_2268165_-	glycosyltransferase	A0A1V0SAH6	Catovirus	3.5e-07	29.9
WP_002380621.1\|2268234_2269701_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_002367103.1\|2269719_2270889_-	CDP-glycerol glycerophosphotransferase family protein	NA	NA	NA	NA
WP_002380622.1\|2271361_2272162_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_095714924.1\|2272158_2272974_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	3.6e-22	42.4
WP_002359679.1\|2273321_2274140_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002362617.1\|2274154_2274841_-	ABC transporter permease	NA	NA	NA	NA
WP_002356639.1\|2274833_2275871_-	methionine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.8e-30	35.2
WP_011109554.1\|2276285_2276600_-	glycine cleavage system protein H	NA	NA	NA	NA
WP_002359675.1\|2276605_2276965_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	3.5e-30	56.9
WP_002356636.1\|2276989_2278177_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_002380625.1\|2278420_2279857_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002356634.1\|2279857_2280559_-	hypothetical protein	NA	NA	NA	NA
WP_010783437.1\|2280757_2285713_-	fibrinogen-binding MSCRAMM adhesin Fss2	NA	NA	NA	NA
WP_002380627.1\|2285888_2287220_-	hypothetical protein	NA	NA	NA	NA
WP_002362234.1\|2287332_2287884_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002356628.1\|2288097_2288805_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_002380629.1\|2288791_2289118_+	AzlD domain-containing protein	NA	NA	NA	NA
2289162:2289183	attL	NA	NA	NA	NA
WP_047648925.1\|2289310_2289757_-	hypothetical protein	NA	NA	NA	NA
WP_048943050.1\|2289855_2290959_-	N-acetylmuramoyl-L-alanine amidase	V5URN7	Enterococcus_phage	5.1e-88	49.3
WP_002370806.1\|2290999_2291209_-	hypothetical protein	A0A0S2MYG0	Enterococcus_phage	1.8e-15	60.6
WP_002370808.1\|2291214_2291340_-	XkdX family protein	NA	NA	NA	NA
WP_016630605.1\|2291339_2291774_-	hypothetical protein	NA	NA	NA	NA
WP_048943051.1\|2291792_2293262_-	hypothetical protein	D2J018	Enterococcus_phage	7.2e-106	71.6
WP_048943048.1\|2293320_2293929_-	DUF2313 domain-containing protein	Q20DB9	Lactobacillus_phage	4.3e-12	31.5
WP_010774485.1\|2293925_2295068_-\|plate	baseplate J/gp47 family protein	Q708L2	Streptococcus_phage	6.9e-88	43.7
WP_048943047.1\|2295064_2295448_-	DUF2634 domain-containing protein	Q708L3	Streptococcus_phage	4.7e-25	51.6
WP_002370819.1\|2295451_2295754_-	DUF2577 family protein	X2CXE6	Lactobacillus_phage	1.5e-10	36.8
WP_047648921.1\|2295754_2296729_-	hypothetical protein	Q708L5	Streptococcus_phage	1.9e-70	42.7
WP_002370821.1\|2296725_2297403_-	hypothetical protein	Q708L6	Streptococcus_phage	2.6e-42	41.7
WP_048943046.1\|2297413_2302390_-	tape measure protein	Q5YA61	Bacillus_phage	9.7e-70	50.7
WP_002409362.1\|2302399_2302588_-	hypothetical protein	NA	NA	NA	NA
WP_002409363.1\|2302587_2302983_-\|portal	phage portal protein	Q20DC6	Lactobacillus_phage	1.9e-16	38.5
WP_002370824.1\|2303048_2303513_-\|tail	phage tail tube protein	Q708L9	Streptococcus_phage	9.4e-36	50.0
WP_016630610.1\|2303535_2304837_-	hypothetical protein	Q708M0	Streptococcus_phage	2.3e-111	50.9
WP_010774481.1\|2304836_2305034_-	hypothetical protein	NA	NA	NA	NA
WP_095714925.1\|2305026_2305452_-	hypothetical protein	NA	NA	NA	NA
WP_002370828.1\|2305444_2305918_-	HK97 gp10 family phage protein	A0A0A7RTT0	Clostridium_phage	2.7e-22	42.6
WP_002409366.1\|2305914_2306277_-	hypothetical protein	X5JAV9	Clostridium_phage	4.2e-07	33.0
WP_002409367.1\|2306281_2306665_-	hypothetical protein	NA	NA	NA	NA
WP_002370832.1\|2306670_2307702_-	hypothetical protein	Q708M6	Streptococcus_phage	1.8e-71	45.2
WP_002370834.1\|2307704_2308286_-	hypothetical protein	Q9T1B8	Listeria_phage	1.3e-18	37.8
WP_002409369.1\|2308529_2308754_-	hypothetical protein	NA	NA	NA	NA
WP_002409370.1\|2308750_2310466_-\|capsid	minor capsid protein	X2CXX3	Lactobacillus_phage	6.6e-50	35.3
WP_000195429.1\|2311227_2312400_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_002409372.1\|2313199_2314522_-\|terminase	PBSX family phage terminase large subunit	V5UTH5	Oenococcus_phage	2.1e-157	63.7
WP_002409373.1\|2314499_2315351_-\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	7.9e-89	73.8
WP_002370841.1\|2315409_2315598_-	hypothetical protein	C9E2P9	Enterococcus_phage	1.8e-25	98.4
WP_016024386.1\|2315733_2315925_-	hypothetical protein	D2IZZ6	Enterococcus_phage	1.1e-25	100.0
WP_048948861.1\|2315962_2317297_-	ParB N-terminal domain-containing protein	D2IZZ5	Enterococcus_phage	8.5e-231	89.9
WP_048948862.1\|2317299_2317533_-	hypothetical protein	NA	NA	NA	NA
WP_010824919.1\|2318257_2318674_-	ArpU family phage transcriptional regulator	C9E2P5	Enterococcus_phage	9.9e-69	99.3
WP_002409380.1\|2318818_2319019_-	hypothetical protein	D2IZZ2	Enterococcus_phage	4.6e-32	98.5
WP_002389222.1\|2319201_2319384_-	hypothetical protein	C9E2P1	Enterococcus_phage	5.9e-26	100.0
WP_095714887.1\|2319384_2319870_-	hypothetical protein	C9E2P0	Enterococcus_phage	2.4e-90	99.4
WP_002409382.1\|2319883_2320468_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	3.1e-92	85.1
WP_002409383.1\|2320479_2320683_-	hypothetical protein	NA	NA	NA	NA
WP_002409384.1\|2320694_2320889_-	hypothetical protein	NA	NA	NA	NA
WP_002409386.1\|2320892_2321099_-	hypothetical protein	NA	NA	NA	NA
WP_086281315.1\|2321293_2321548_-	hypothetical protein	NA	NA	NA	NA
WP_095714886.1\|2321550_2322924_-	hypothetical protein	A8ATM0	Listeria_phage	2.1e-131	53.5
WP_002409390.1\|2322920_2323340_-	hypothetical protein	Q7Y4K2	Streptococcus_phage	5.0e-20	47.9
WP_095714885.1\|2323340_2324294_-	phage replisome organizer	C9E2N2	Enterococcus_phage	1.4e-94	65.2
WP_010711641.1\|2324297_2324978_-	hypothetical protein	A0A0S2MYA3	Enterococcus_phage	1.3e-113	87.2
WP_047648904.1\|2324974_2325868_-	DUF1351 domain-containing protein	A0A0S2MYB3	Enterococcus_phage	4.2e-48	43.0
WP_002370859.1\|2325880_2326567_-	ERF family protein	Q6JM07	Lactococcus_phage	3.0e-22	44.9
WP_095714884.1\|2326567_2326804_-	hypothetical protein	A0A0S2MYD6	Enterococcus_phage	1.8e-27	82.7
WP_048943097.1\|2326787_2327207_-	hypothetical protein	NA	NA	NA	NA
WP_048943098.1\|2327227_2327419_-	hypothetical protein	A0A0S2MYB0	Enterococcus_phage	1.2e-18	94.1
WP_048943099.1\|2327555_2328284_-	hypothetical protein	NA	NA	NA	NA
WP_047648901.1\|2328267_2328483_-	hypothetical protein	NA	NA	NA	NA
WP_047648900.1\|2328624_2328951_-	DUF771 domain-containing protein	A0A1B1IMW0	Lactococcus_phage	3.9e-12	35.6
WP_047648899.1\|2328937_2329645_-	toxin-antitoxin system, toxin component, Bro family protein	Q9AZW1	Lactococcus_phage	2.4e-51	48.7
WP_047648898.1\|2329697_2329892_-	helix-turn-helix transcriptional regulator	A0A2H4JBA4	uncultured_Caudovirales_phage	3.8e-07	42.4
WP_048943100.1\|2330043_2330682_+	helix-turn-helix domain-containing protein	A0A1B2APZ3	Phage_Wrath	4.9e-59	53.3
WP_047648896.1\|2330788_2331922_+\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	1.9e-122	57.7
WP_002381528.1\|2332227_2332464_+	hypothetical protein	NA	NA	NA	NA
2331991:2332012	attR	NA	NA	NA	NA
WP_002356625.1\|2332537_2332810_-	membrane protein	NA	NA	NA	NA
WP_002356624.1\|2332915_2333545_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_002356623.1\|2333676_2334915_-	serine hydroxymethyltransferase	A0A219YB23	Aeromonas_phage	1.3e-103	54.9

DBSCAN-SWA_13

2536279 : 2546019

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002392852.1\|2536279_2538463_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	8.9e-286	66.6
WP_002356379.1\|2538495_2539092_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
WP_002380775.1\|2539136_2540255_-	DNA polymerase IV	NA	NA	NA	NA
WP_002380776.1\|2540380_2541139_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002356375.1\|2541122_2541785_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
WP_002359438.1\|2541799_2542672_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-80	57.2
WP_002356372.1\|2542783_2543131_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_002356371.1\|2543123_2543963_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002384059.1\|2544079_2545030_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356367.1\|2545031_2545361_-	hypothetical protein	NA	NA	NA	NA
WP_002380777.1\|2545380_2546019_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8

DBSCAN-SWA_14

2566815 : 2613838

Enterococcus_phage(39.47%)

capsid,plate,head,portal,terminase,tail,protease,holin,integrase,tRNA

attL 2575567:2575584|attR 2609278:2609295

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002362481.1\|2566815_2567526_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_002380787.1\|2567536_2568079_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_002356329.1\|2568166_2568937_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_002356327.1\|2569102_2569678_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_002385675.1\|2569768_2571340_+	membrane protein	NA	NA	NA	NA
WP_002370554.1\|2571426_2572593_-	CHAP domain-containing protein	M1Q1Y5	Streptococcus_phage	8.5e-09	49.2
WP_002362349.1\|2572681_2573062_-	hypothetical protein	C9E2L2	Enterococcus_phage	1.6e-36	59.5
WP_002356323.1\|2573751_2574816_-	FUSC family protein	NA	NA	NA	NA
WP_002393583.1\|2575071_2575323_-	hypothetical protein	NA	NA	NA	NA
2575567:2575584	attL	NA	NA	NA	NA
WP_002380790.1\|2575827_2577087_-	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	1.8e-230	93.3
WP_002380792.1\|2577089_2577296_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	2.6e-30	100.0
WP_002367247.1\|2577298_2577532_-\|holin	holin	D2J075	Enterococcus_phage	7.0e-24	70.2
WP_002380794.1\|2577566_2577704_-	XkdX family protein	NA	NA	NA	NA
WP_010714092.1\|2577703_2578078_-	hypothetical protein	NA	NA	NA	NA
WP_010774945.1\|2578092_2578647_-	hypothetical protein	NA	NA	NA	NA
WP_002357046.1\|2578646_2578934_-	collagen-like protein	NA	NA	NA	NA
WP_002357045.1\|2578930_2579527_-	hypothetical protein	NA	NA	NA	NA
WP_010774946.1\|2579519_2580401_-\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	6.9e-11	26.1
WP_002380798.1\|2580415_2583142_-	peptidoglycan DD-metalloendopeptidase family protein	A0A191KC22	Streptococcus_virus	2.2e-100	41.7
WP_002380799.1\|2583138_2583843_-\|tail	phage tail protein	NA	NA	NA	NA
WP_002380800.1\|2583845_2586143_-\|tail	phage tail tape measure protein	V5UPR9	Enterococcus_phage	1.8e-79	56.0
WP_002380802.1\|2586334_2586790_-	hypothetical protein	A0A2H4J956	uncultured_Caudovirales_phage	2.6e-14	37.4
WP_162565054.1\|2586789_2587425_-\|tail	phage tail protein	A0A2H4JGN2	uncultured_Caudovirales_phage	1.5e-28	34.5
WP_002380805.1\|2587430_2587793_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_002380807.1\|2587782_2588121_-	hypothetical protein	A0A1B0T6B7	Bacillus_phage	2.1e-24	51.4
WP_095715026.1\|2588110_2588437_-\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	6.2e-18	50.0
WP_002380811.1\|2588396_2588684_-	hypothetical protein	A0A1C8E967	Bacillus_phage	1.3e-11	42.5
WP_002380812.1\|2588686_2590018_-\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	1.1e-71	44.3
WP_002380813.1\|2590017_2590602_-\|head,protease	HK97 family phage prohead protease	A0A1B2APW1	Phage_Wrath	5.0e-50	54.6
WP_002398478.1\|2590585_2591719_-\|portal	phage portal protein	A0A1B2APW5	Phage_Wrath	3.0e-83	46.1
WP_002380815.1\|2591773_2593507_-\|terminase	terminase large subunit	A0A1B2AQ28	Phage_Wrath	6.8e-196	58.3
WP_002380816.1\|2593503_2593962_-\|terminase	terminase	A0A1B2APW6	Phage_Wrath	1.6e-24	44.0
WP_002380817.1\|2594064_2594448_-	HNH endonuclease	A0A2H4JFG4	uncultured_Caudovirales_phage	2.3e-19	44.0
WP_002380818.1\|2594440_2594728_-	hypothetical protein	NA	NA	NA	NA
WP_002380819.1\|2595253_2595721_-	ArpU family transcriptional regulator	D7RWH7	Brochothrix_phage	1.7e-08	27.8
WP_002380820.1\|2596050_2596251_-	hypothetical protein	D2IYV2	Enterococcus_phage	1.8e-31	100.0
WP_010774950.1\|2596254_2596776_-	DUF1642 domain-containing protein	D2IZL3	Enterococcus_phage	1.2e-44	55.1
WP_010774951.1\|2596772_2596952_-	hypothetical protein	A0A0B5A0A5	Streptococcus_phage	9.2e-16	70.7
WP_002380822.1\|2597106_2597415_-	hypothetical protein	A0A0S2MYE8	Enterococcus_phage	4.0e-59	100.0
WP_010774953.1\|2597415_2597790_-	hypothetical protein	D2IZL0	Enterococcus_phage	1.3e-43	72.6
WP_002380824.1\|2597833_2598598_-	site-specific DNA-methyltransferase	A0A097QQ03	Enterococcus_phage	7.2e-142	98.8
WP_002380826.1\|2598650_2598857_-	hypothetical protein	A0A1B1V001	Enterococcus_phage	4.8e-24	95.2
WP_002380827.1\|2598872_2599478_-	hypothetical protein	NA	NA	NA	NA
WP_002380828.1\|2599497_2599968_-	DUF1064 domain-containing protein	A0A1I9KKZ1	Lactobacillus_phage	1.9e-31	45.9
WP_002380830.1\|2600116_2600386_-	hypothetical protein	NA	NA	NA	NA
WP_002380831.1\|2600524_2601364_-	ATP-binding protein	F0PII2	Enterococcus_phage	1.7e-19	34.1
WP_002380832.1\|2601375_2602155_-	DnaD domain protein	Q6J1V6	Lactobacillus_phage	1.2e-38	60.2
WP_002380833.1\|2602169_2602985_-	hypothetical protein	J7KGZ1	Streptococcus_phage	3.9e-61	50.6
WP_002380835.1\|2602947_2603964_-	recombinase RecT	A0A1S5SAA8	Streptococcus_phage	1.1e-60	45.2
WP_010774955.1\|2604056_2604413_-	hypothetical protein	NA	NA	NA	NA
WP_002367281.1\|2604415_2604640_-	hypothetical protein	D2IZX4	Enterococcus_phage	3.7e-22	68.5
WP_010706856.1\|2604636_2604936_-	hypothetical protein	NA	NA	NA	NA
WP_002380838.1\|2605022_2605439_-	hypothetical protein	NA	NA	NA	NA
WP_002367284.1\|2605644_2605914_-	hypothetical protein	NA	NA	NA	NA
WP_002358110.1\|2605926_2606109_-	hypothetical protein	NA	NA	NA	NA
WP_002373919.1\|2606405_2606738_+	helix-turn-helix transcriptional regulator	D2IZV9	Enterococcus_phage	5.5e-30	60.0
WP_002380839.1\|2606756_2607101_+	ImmA/IrrE family metallo-endopeptidase	D2IZV8	Enterococcus_phage	3.3e-46	78.9
WP_002380840.1\|2607158_2607887_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	6.9e-17	50.8
WP_002380841.1\|2608041_2609223_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	2.5e-48	31.8
WP_002356321.1\|2609325_2609475_-	50S ribosomal protein L33	NA	NA	NA	NA
2609278:2609295	attR	NA	NA	NA	NA
WP_002359399.1\|2609600_2611736_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_002380843.1\|2611900_2613838_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.8e-112	36.3

DBSCAN-SWA_15

2681753 : 2725383

Staphylococcus_phage(26.67%)

transposase,tRNA,integrase

attL 2675769:2675784|attR 2708605:2708620

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2675769:2675784	attL	NA	NA	NA	NA
WP_095715010.1\|2681753_2684396_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	4.4e-162	42.9
WP_002355111.1\|2684787_2685276_-	thiol peroxidase	NA	NA	NA	NA
WP_002380866.1\|2685339_2685987_-	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_002303110.1\|2686261_2687299_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_002387940.1\|2687295_2687808_-\|transposase	transposase	NA	NA	NA	NA
WP_002359156.1\|2687897_2689112_-\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_002380868.1\|2689203_2690322_-\|integrase	site-specific integrase	Q8SBN2	Clostridium_phage	5.2e-32	31.7
WP_002393063.1\|2690602_2690959_-	hypothetical protein	NA	NA	NA	NA
WP_002371404.1\|2691024_2691561_-	hypothetical protein	NA	NA	NA	NA
WP_002371406.1\|2691557_2691782_-	hypothetical protein	NA	NA	NA	NA
WP_002393064.1\|2691794_2692823_-	CHAP domain-containing protein	A0A0B4MZ94	Streptococcus_phage	6.8e-10	32.2
WP_095715024.1\|2692865_2694917_-	hypothetical protein	NA	NA	NA	NA
WP_002371410.1\|2694932_2697437_-	ATP-binding protein	NA	NA	NA	NA
WP_002371413.1\|2697700_2698009_+	hypothetical protein	NA	NA	NA	NA
WP_095715025.1\|2698087_2698477_-	conjugal transfer protein	NA	NA	NA	NA
WP_002371416.1\|2698485_2698710_-	hypothetical protein	NA	NA	NA	NA
WP_002371418.1\|2698709_2699696_-	conjugal transfer protein	NA	NA	NA	NA
WP_002380870.1\|2699676_2700144_-	hypothetical protein	NA	NA	NA	NA
WP_002371420.1\|2700140_2700683_-	hypothetical protein	NA	NA	NA	NA
WP_002371421.1\|2700822_2703570_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002371422.1\|2703729_2704752_-	hypothetical protein	NA	NA	NA	NA
WP_002393069.1\|2704846_2705458_-	hypothetical protein	A0A1W6JN36	Lactococcus_phage	2.1e-19	65.6
WP_002393070.1\|2705535_2706819_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	3.1e-44	30.5
WP_002410060.1\|2707139_2707547_-	hypothetical protein	NA	NA	NA	NA
WP_002371426.1\|2707556_2707844_-	hypothetical protein	NA	NA	NA	NA
WP_002371427.1\|2707833_2708112_-	hypothetical protein	NA	NA	NA	NA
WP_002380872.1\|2708130_2709639_-	cell division protein FtsK	A0A1S5SFB5	Streptococcus_phage	4.0e-67	36.7
2708605:2708620	attR	NA	NA	NA	NA
WP_002371429.1\|2709639_2710020_-	DUF86 domain-containing protein	NA	NA	NA	NA
WP_002393071.1\|2710009_2710336_-	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_002394269.1\|2710395_2710689_-	hypothetical protein	NA	NA	NA	NA
WP_002371434.1\|2711109_2711298_+	hypothetical protein	NA	NA	NA	NA
WP_002380876.1\|2711468_2711885_-	DUF961 family protein	NA	NA	NA	NA
WP_002365226.1\|2711884_2712211_-	hypothetical protein	NA	NA	NA	NA
WP_002365227.1\|2712296_2712548_-	hypothetical protein	NA	NA	NA	NA
WP_000195429.1\|2712718_2713891_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_002380877.1\|2714624_2715008_+	helix-turn-helix transcriptional regulator	E9LUL4	Lactobacillus_phage	4.7e-17	62.1
WP_002380879.1\|2715004_2715658_+	ImmA/IrrE family metallo-endopeptidase	S4U0J6	uncultured_phage	4.6e-12	34.9
WP_002365231.1\|2715696_2716032_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002380880.1\|2716069_2717401_-	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.5e-134	54.4
WP_002393072.1\|2717500_2718436_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	8.5e-44	36.2
WP_002380882.1\|2718451_2718871_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_002380883.1\|2718887_2719469_-	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	3.0e-31	42.1
WP_000195429.1\|2719730_2720903_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_002380886.1\|2721090_2721318_-	hypothetical protein	NA	NA	NA	NA
WP_002371724.1\|2721408_2721609_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.1e-23	78.8
WP_002380887.1\|2722356_2723154_-	hypothetical protein	NA	NA	NA	NA
WP_095715053.1\|2723208_2723673_-	hypothetical protein	NA	NA	NA	NA
WP_000195429.1\|2724210_2725383_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0

Anti-CRISPR protein detection

Acr_ID: NZ_CP029612.1|WP_025188165.1|865832_866018_-|DUF1508-domain-containing-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP029612.1|WP_025188165.1|865832_866018_-|DUF1508-domain-containing-protein

865832_866018_-

61 aa aa

839307-881458

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP029612_1	Orphan	1.2\|1901785\|30\|NZ_CP029612\|CRISPRCasFinder,PILER-CR	1901785-1901814	30	868875-868846	0

1. spacer 1.2|1901785|30|NZ_CP029612|CRISPRCasFinder,PILER-CR matches to NZ_CP029612 position: 868875-868846, mismatch: 0

aacgtttttagggatccaaatacctttaaa	CRISPR spacer
aacgtttttagggatccaaatacctttaaa	Protospacer
******************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP029612

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information