CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP016552	Geobacillus stearothermophilus strain DSM 458 chromosome, complete genome	9 crisprs	cas14k,cas2,cas1,cas9,cas6,csa3,RT,cas14j,DEDDh,c2c4_V-U1,cas3,DinG,cas4,cas5,cas7,cas8b2	1	28	20	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP016552_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_1

342636-342798

TypeII

Consensus_repeat	Method
GTTTTTATCGTACCTATGAGGGATTGAAACG	PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder

2 spacers

cas2,cas1,cas9,cas6

The CRISPR arrays of NZ_CP016552_1

>merge|NZ_CP016552|1|342636-342798|PILER-CR,CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAACGACCGTTCTCTAGCATGTCCTTAGTCTCGTTTGTTGTTTTTATCGTACCTATGAGGGATTGAAACGCGGCTCGGTATTTGTTACATTTACGTCTAACGATCCGTTTTTATCGTACCTATGAGGGATTGAAACA

>NZ_CP016552|1|1|342636-342798|PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAACG	ACCGTTCTCTAGCATGTCCTTAGTCTCGTTTGTT
GTTTTTATCGTACCTATGAGGGATTGAAACG	CGGCTCGGTATTTGTTACATTTACGTCTAACGATCC
GTTTTTATCGTACCTATGAGGGATTGAAACA

>NZ_CP016552|1|1|342636-342797|CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	GACCGTTCTCTAGCATGTCCTTAGTCTCGTTTGTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCGGCTCGGTATTTGTTACATTTACGTCTAACGATCC
GTTTTTATCGTACCTATGAGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_095858794.1\|335498_336695_+\|TIGR02678-family-protein	unknown	unknown	gnl\|CDD\|274254
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NZ_CP016552.1\|WP_095858801.1\|355451_355661_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376019
NZ_CP016552.1\|WP_095860175.1\|326604_327087_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP016552.1\|WP_095858795.1\|336654_340776_+\|TIGR02680-family-protein	unknown	unknown	gnl\|CDD\|274256
NZ_CP016552.1\|WP_101878866.1\|325465_326368_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858793.1\|334005_335496_+\|TIGR02677-family-protein	unknown	unknown	gnl\|CDD\|131724
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP016552.1\|WP_095858791.1\|328138_329626_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225962
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	unknown	unknown	gnl\|CDD\|274255
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	unknown	unknown	gnl\|CDD\|237372
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|225943
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP016552.1\|WP_095858792.1\|329644_330145_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225937
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_020756630.1\|324967_325450_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_095858794.1\|335498_336695_+\|TIGR02678-family-protein	gnl\|CDD\|274254	TIGR02678, hypothetical_protein, TIGR02678 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	1.30358e-151
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	gnl\|CDD\|376019	pfam18593, CdiI_2, CdiI immunity protein. Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Structure analysis of CdiI immunity protein from Yersinia kristensenii shows that it is composed of eight alpha-helices packed together to form a nearly spherical structure with weak structural homology to a putative TetR family transcriptional repressor. The CdiI protein fits into the curved cavity of the CdiA-CTYkris toxin domain where it most likely neutralizes toxin activity by blocking access to RNA substrates. This domain is mostly found in gammaproteobacteria.	0.000887762
NZ_CP016552.1\|WP_095860175.1\|326604_327087_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.85638e-55
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.31022e-42
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.29636e-10
NZ_CP016552.1\|WP_095858795.1\|336654_340776_+\|TIGR02680-family-protein	gnl\|CDD\|274256	TIGR02680, conserved_hypothetical_protein, TIGR02680 family protein. Members of this protein family belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). Proteins in this family average over 1400 amino acids in length. [Hypothetical proteins, Conserved].	0
NZ_CP016552.1\|WP_095858793.1\|334005_335496_+\|TIGR02677-family-protein	gnl\|CDD\|131724	TIGR02677, conserved_hypothetical_protein, TIGR02677 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	0
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP016552.1\|WP_095858791.1\|328138_329626_-\|PH-domain-containing-protein	gnl\|CDD\|225962	COG3428, COG3428, Predicted membrane protein [Function unknown].	1.86702e-55
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	gnl\|CDD\|274255	TIGR02679, conserved_hypothetical_protein, TIGR02679 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	2.0043e-132
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.05989e-06
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	gnl\|CDD\|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	1.14699e-06
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	gnl\|CDD\|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	1.80502e-24
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.47396e-99
NZ_CP016552.1\|WP_095858792.1\|329644_330145_-\|PH-domain-containing-protein	gnl\|CDD\|225937	COG3402, COG3402, Uncharacterized conserved protein [Function unknown].	1.96866e-29
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.50141e-44
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.53622e-36

>NZ_CP016552.1|WP_095858797.1|342060_342438_+|transposase
MLARLELDEAKQRLLFGFFETYLRRSEEEEAKRRHEVSQMETKEAKQVMELIVSYEQRGMEKGIEKGIEQGVKQGIKQGIKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858796.1|340772_341993_+|TIGR02679-family-protein
MSTAKEAAAFFRSEPGFRRLFIEMKHKYESLGRVGGAVSLEAFTDEEREAVAAFFGKDVSRVSLIAFEKQLGQTRFAGVGLVELLEQYFGAPLVSNKERRQAEEEERDRFFARLTEEHHWVESVRPQRFVQTAYETDRRSLEEAIRLVSAALGRLPLPSYMRLPLFAQQVAGDPHAFDLSTLPGRLLLSALQATVPGDWDMASVESVNELLQSVGLLREDILNFVTCANILAETEGGPHPVFSAASETNTALNMPLRDVLSLVRARPAHGGTVYIVENAGVFSTLLDTRAPLVSTNGQMNLATMKLLDLLASSGAKLYYSGDFDPEGLAMAERLQERYGQAVTLWRFSVEDYRAANPVVDLTPERLAKLASVTSTPLQPLKEEMAETKKAGYQEAIIGRLTGDING
>NZ_CP016552.1|WP_095858795.1|336654_340776_+|TIGR02680-family-protein
MANPWVLHRAGLINFWYYDEQYFHFADGKLLLRGSNGAGKSVTMQSLIPVLLDGKKTPDRLDPFGSRARRMEDYLLGEKDVVNRDERTGYLFLEYKRKASDQYVTTGIGLRAKRQKSLDFWGFVIFDNRRIGHHLTLYKKEKTGEKIPLTKRELAALLGAGGTVVDTQKEYMELVNKHVFRFESLESFQELIELLIQLRSPKLSKDFKPTVIYEILESSLPPLTDDELRHLSDTIENMDQAKQQLEQLERDERALKRLCDQYRLYNEYMIAEKAAEYVKAVKQAEQLAAEQQRLHDEEERARTMLDELEESITRLGREEDVLRAREIDLAGHEVFQQAEKYEQLKAEQQRLEERRKRHEQTIAEKERQERQHRRRLDEAEARLDDLERKLEDELEQLRMDADEGSFSLHETNEGDFHRHRQKEQEFLFAAWKQEADRHIERLEGLARLWRRHDEVKQRYEEASSEAGERQREMDEWRHQQRKWEELLEQEKERFEQAVLAWIGQGDVDISEADIQSFLQQMDALYEQYSLDDLKRPFVQAYYDAVGKKKDEKWRLEHDIRLLEEKRAEREAELRRWREQRDPEPERDEQTTAARLALEEKGIPFVPLYAAVEFVDDVPDDVRERIESALSHAGLLDALITAREIDVACDRVLIPKPVHMAHTLADYLRPDANAPVSMERIDEVLRSIVITDADQEGGMTIDETGRYSLGLVRGHAPRRSKAMFIGRAARERWRLENIAALEAEIAAVGQEIDRLRGAHEDVEAAIQALADWLASFPSDRDVRTAFDEAQEARRQAESKEREWKRQEEKAALLAREWKQIKQQLRDESAELDLAFTLDGCEQAMLAMKSYVRHLHELEVLYRETRHTEAVIAQQREQLAVLEAEIDEAKGERNRLRDETERLALRIAEMERTLAQMGADDIRAEIARIQERLASLRREIPRLVNERARTEQQLMRLVEEREKGAQREEFARELAAMWEKSFAREAALGLVDLDRSRSLLEQAKEAKQRYEAVLKETRSSLLARLNTVFFQESSNLTEYRASFEPLEEQTKPEWTAAAPDDEMAMKAADWREKQERHVIYLDYKGERATPFAVLAEVERDIVLQHEYMKEQDRELYEDVILKSVGRILRSRIQRAERWVNDMNKLMGGLDTSSGLVLSIQWKPKTAETEAELDTKELVRLLRLDPRLLREEDLQRVTNHFRSKIARARELLEERGQGSTLHQIIKEVLDYRKWFSFTLYYEKTNEPKRELTNHRFYQFSGGEKAMAMYIPLFAAAYSRYQEAGDDAPYIISLDEAFAGVDENNIRNLFGLVEQLGFNYIMNSQALWGDYDTVPALSICELVRPRNASFVTVIHYRWNGRVKQLMVNDKEWETIET
>NZ_CP016552.1|WP_095858794.1|335498_336695_+|TIGR02678-family-protein
METAFDDKAKEALAALFEQFWIIRDQEPDLYQLVREREHVLKRYVEEKFGYRLIVHRYFAKLEKIPADPEPWMGIESFQEPLDYALFCCLMAYLEGKAVEEKFLLSDVCEEIRAMYPGDLPVDWTNYAHRRALIRVLKTAEQIGLVRRMDGEIEAFAQHAEEEALYEVPVLARYFMRTHPKDLLRYESIEELMAEEWKASPQDYRRHRLYRKLFLSPAVHRTEGDEQDFYYLRNFRHRLRDDIEAHTPFRYELYKNAAMLTLPERQAPYTTFPDQKGTSEIILHFSALVRERLGEYPPDEYGRIRLTPEQFSAWLADCRRRYGAGWGKTYRDMSAAELVREVLAALCEWRMADVEHDTGMIVLYPLLGRVAGRYPDDFDAKEGGEHGESMGASSCGAD
>NZ_CP016552.1|WP_095858793.1|334005_335496_+|TIGR02677-family-protein
MDATWLKPIVETKYLSTENAHRYRAILRYFYIQHERMRQYLFPEEVYAFLKQHEEFADYTEDDLQQDLDQLVKWNNLIARQETSHVRTIEEFKKKRFRYQCSPYTVEIERMIRTLEQLGDSFGGSLEKTRFDRLYASLSRIEAIIASGFQEQRDEMYQVWEETFDYFKKIIQNSADYMAYLHSENVEERMTSESFLVYKEQFTAYLRDFIVALQKTSMQIEQLLEDLPEEGVRQFIGHVVDYERSIPRFADAPPPRAVQIEEKWETWRSLCEWFLGRNGRESELSFLQYQTNEAIRRLTRVVQRLGERHHHFRSRKGDYLHLARWFSRLESIEEAHCLSAVVFGCFHTKHLVADAEATDNIYRDVWDEPPAEWVTKPRVRHYGEKKKPQAIEDKEREKEEARLRYLEEKAREEAELKQFVTDGKIVLADLPEVTPYVRKTLLGWIAKAMGREGQAMKTENGWVVNVVNKEGTICLRAEDGELVMPNYEIHVLSGGE
>NZ_CP016552.1|WP_095858792.1|329644_330145_-|PH-domain-containing-protein
MTQTIKEPKQQISPNAVKVWRISDAITYFITLCILTVLLYLQHYYDWKNWVGVILYFIVILVIISSIVEIIFVPIYRQKTWRYDVDEKYIQLKYGGVFMKTHLIIPMTKVQYVNTIQGPLLRKFGLSTIKIGTMASVHEIPAIPEKKATELREKIAYLAGVNESDE
>NZ_CP016552.1|WP_095858791.1|328138_329626_-|PH-domain-containing-protein
MNNEITNDQARRIHPLWIFFSIGKSIKELVLFVITFIIYIRSDSDSILIKITGIAIVFYLIYKIVSILLEWFHFKYLFTNKELYIHEGRFIKEKRYIPLERIQGIKRTTPFFHRLFGLTSLILDTGASGNKSTIKLGMITCEEAERIQKHLSHISSFHKDKGVSEQNVQTSKEIAPELSSRKKYYEMTSKEIFVASVTSLSLLIFLSVLYTIYDNVSDFFSIDSYIDTVISFFQKSWLLTFLGIVALLMLSMAYGWARTYVIYRNFEVTGDNQRIYIRKGLFNQTEFSIPKEKVEAIILNTKLLKKILGIVEVKIISTGDGDENEMKTANILFPFIDKRRALSLIPQIFPAFHVETEMVNLPRSAIFVKLVRTSYIWIIAAAINFYFWPNFWYISVALFVLINTSQLLSGLYSCYNLCGPFIQIQTGSFSTKLFITTRMKIEELKVTESLLQRMFGLASLEISTRSKSIQVSKISDIPKDMAIRYYQWYANKENH
>NZ_CP016552.1|WP_095860175.1|326604_327087_-|ABC-transporter-ATP-binding-protein
MAVKALEVRSLTKKVKNKVIVDDVSFVVEKGEIFGLLGPNGAGKTTIIRMIVGLIGRTKGSVYVNGYNLDEQFKEAMSEIGAIVENPEFYKYMSGYKNLKHYANMARHKVTEERIQEVIRVVGLEQVIHQKVKTYSLGMRQRLGLAQALGSSPKGVLDFF
>NZ_CP016552.1|WP_101878866.1|325465_326368_+|hypothetical-protein
MKKKFLIAGVASVVLAVSLVVYNGTDIAGSQDNVAQASANIQKVKVQNTDEQKTKIQTLMLNSIDHYKTAKGSFEYFSESGNFHISVDYQTDLSDSPKSYEKVRGLAKENKNGITTAAEPGYEVSVYDGENLINYNSGSSDYQTNSVTKSNVPIKTIVKVGKVSEKERNYLKNTTIHERITTVDGEKAYIHRIDPSYMGIAKTSLFPEDIAMGLLADDARWDITGQENIAGVKTVVIEGKLNSEYSKRYNAKTFKLNIEPNTGIMIQMEVFDSSGTIKESIKTKNIEINKSLDTKLFTSF
>NZ_CP016552.1|WP_020756630.1|324967_325450_+|hypothetical-protein
MFKKGYLSILSLVMGFTFFSTNTFAATDIVDNDALSSAPGYCEQKGNWTYKTGSGYYNDYRIVSATVNGFDTDYAYIWGFYAHDKNAAHYVYLNNKDFTNPRTAYQIDEFGGIVYINQNTAPGGWNFLKTHKEWNHMIVINTSLTTKLGNVGADATKITY
>NZ_CP016552.1|WP_015374552.1|342855_343901_-|IS630-like-element-ISBs2-family-transposase
MMPNHKDEIEKLSTAMKEAKSKRAYERYQAIYLHLQGYTKGEIATIIGRSKKTIYNYIHAYAQRGLDGLEMKYSPGAPRRLTPEQEKELALIIEHQLPVDVGFEAKYNWTLAIIAELIQQKWGPTYTLRGTSDILHRLGLSYTKPTYTLANADEEKQKEFVEITFPEVKKLVDGNIAHVLFQDESMIRDYQAIQKTWFVKGKQRIIPTFGKHQGLKLIGTLNYETGEVFCIEEERYDAETFLRFLQLVLERYPTGKIVMILDNARIHHAKLIQPFLKEHEDRLELVFLPPYSPQLNLIEGLWKWLKSDVIYNVFYSSVQEIRKNVQAFIQRINQKPEQTIDRLCVQL
>NZ_CP016552.1|WP_095858798.1|345023_345323_-|hypothetical-protein
MDIRKEFENLQYFFDSYYNQTFYDAKLEDKFLEFLNDEPKWVSKALKEEIKKLEQIYNNKDINTWAKIEELVHENSMRYFPYEDGKKFIEIANKFLENV
>NZ_CP016552.1|WP_095858799.1|345335_346619_-|peptidoglycan-binding-protein
MYVVDASGRHYYPSNYTNYLWNGQTLRKGDRGAYVKTLQSWLHKAGFNPGAIDGIYGANTEKAVKEFQKKVGITADGIAGKQTYNALQSYLRTQTSTSKSTSSTSNNSNDWTGQTLRKGSQGESVKDLQIMLNYAGYNVKVDGIYGSETEKAVRSFQKSVGISVDGIAGAQTYKSLNSYISSKANKGVTIDISKEAQRLQKEAEEKKKQELAKALIDVATDFVPVVGQFKDAYNLVNTLFNPNATAKEVGLALFAFIPAVGDLKNIGKAIDAIKSTVKKGTDKIDDAAIDFISKKIREINASDLLLYSEKAGGHTISEHISLSDTQMVKRAAQQKIDVTSYTNQNTAIKVIKSALSQNASKIAEWLLDPNSRDRLNLNQEMGYAIGKGYKSGGTALKTNLDTAFIQLKKDSKSKYGFIIVTSYPKYK
>NZ_CP016552.1|WP_033016933.1|349881_350190_-|CRISPR-associated-endonuclease-Cas2
MRLLVFFDLPVVTNREKREYRRFRTFLLNEGYDMLQFSVYSRVCHGHEATDKHLARLKRNLPPRGSIRAMVVTEKQYAKMQLLLGEPTAQEKKVTSTQLTLF
>NZ_CP016552.1|WP_050368140.1|350194_351094_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRHLLIRKPGKLSVRYNQLVIEQEEKVSIPLEDICSIIIEEQAVSVTAAALSKMAEHNITLFTCDQKRLPNGVLQPFQKHSRQVGVLHMQYAYSKPFKKRIWQRIVIQKLINQGKCLEFLNKEGADDLYRISKTVDSGDSNNREAYGAKKYFQYLFGSEFTRRSDSVVNASLNYGYAIMRGLVARSLVGYGFLPCLGIYHDNELNKFNLADDFMEVLRPLVDLYVAQHIQPDDEFSPSIRADLYNLVNMDILVNGEKLTVVNAVEEMTKSFVTASRSQDPSLLKLPELLPLQLHVYE
>NZ_CP016552.1|WP_095858800.1|351023_354287_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MRYKIGLDIGITSVGWAVINLDIPRIEDLGVRIFDRAENPQTGESLALPRRLARSARRRLRRRKHRLERIRRLVIREGILTKEELDKLFEEKHEIDVWQLRVEALDRKLNNDELARVLLHLAKRRGFKSNRKSERSNKENSTMLKHIEENRAILSGYRTVGEMIVKDPKFALHKRNKGENYTNTIARDDLEHEIRLIFSKQREFGNMSCTEKFENEYITIWASQRPVASKDDIEKKVGFCTFEPKEKRAPKATYTFQSFIAWEHINKLRLISPSGTRGLTDEERRLLYEQAFQKNKITYHDIWTLLRLPDDTYFKGIVYDRGESRKQNENIRFLELDAYHQIRKAVDKVYGKGKSSSFLPIDFDTFGYALTLFKDDADIRSYLQNEYEQNGKRMPNLANKVYDNELIEELLNLSFTKFGHLSLKALRSILPYMEQGEVYSSACERAGYTFTGPKKKQKTMLLPNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARDLSQTFDERRKTKKEQDENRKKNETAIRQLMEYGLTLNPTGHDIVKFKLWSEQNGRCAYSLQPIEIERLLEPGYVEVDHVIPYSRSLDDSYTNKVLVLTRENREKGNRIPAEYLGVGTERWQQFETFVLTNKQFSKKKRDRLLRLHYDENEETEFKNRNLNDTRYISRFFANFIREHLKFAESDDKQKVYTVNGRVTSHLRSRWDFNKNREESDLHHAVDAAIVACTTPSDIAKVTAFYQRREQNKELAKKTEPHFPQPWPHFADELRARLSKHPKESIKALNLGNYDDQKLESLQPVFVSRMPKRSVTGAAHQETLRRYIGIDERSGKIQTVVKTKLSEIKLDASGHFPMYGKESDPRTYEAIRQRLLEHNNDPKKAFQEPLYKPKKNGEPGPIIRTVKIIDTKNQVIPLNDGKTVAYNSNIVRVDVFEKDGKYYCVPVYTMDIMKGILPNKAIEPNKPYSEWKEMTEDYTFRFSLYPNDLIRIELPREKTVKTTTGEEINVKDVFVYYKTIDSATGGLELISHDNRFSLRGVGSRTLKRFEKYQVDVLGNIYKVRGEKRVGLASSAHSKTGETIRPLQSTRD
>NZ_CP016552.1|WP_095860176.1|354681_355047_+|transposase
MLVRLELDEAKQRLLFGFFETYLRLSEEEEAKPRHEVSQMETKEAKRVMELIVSYEQRGLEKGIQQGIEQGIKQGMKQGRQEGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858801.1|355451_355661_+|hypothetical-protein
MITIYDLIGYIQNMDNMDKLDEIISRWYFQTPVWTSQVKEEVKKAVVEILQLGEPKVYQFFVDMYGLKM
>NZ_CP016552.1|WP_095858802.1|355827_356712_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIRTFFEEFLLLFFPDMHEHIDFHHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVETQGYVQPTFAERMFLYFSRLYETYRTRIVPIAVFHYDSLREEPSVFSMEFPFGEVLQFRFFPVALRKKQWREYIRHDNPVAAALLSQMGYTEREKVELKKEFLRMQVRLELDEARQRLLLGFFETYVKLTEEEEQQLQSEVKAMETKEREKVLELIISYEQKGKKEGLEEGVKRGLEQGMKQGMKRLIETMAQKGMTAAEIARLVDLSEEEVRSLLSE
>NZ_CP016552.1|WP_042382835.1|357744_358491_+|CRISPR-associated-endoribonuclease-Cas6
MRLTITMSGRQGPVSLPLHYQHLLQGMLYRSLENEQLAAFLHDKGFRHGKRSFKLFTFSRLFGTHQVDRGKKAIRFLDDFQWHIDTVLPELTQQLGQRFLLQREIELYGQLIEVKSVKMENIDIRENEIDIVMLSPLTVYSTYETFDGRKKTQFFDPDDEVFPHLIELNFRHKYEAYYGVPPTERLLIEPIHVHHRHRVVTMFKNMYITGWLGYYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLKSE

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Crispr_ID: NZ_CP016552_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_2

348561-349780

TypeII

Consensus_repeat	Method
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	CRT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	PILER-CR
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	CRISPRCasFinder
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	PILER-CR

18 spacers

cas2,cas1,cas9,cas6

The CRISPR arrays of NZ_CP016552_2

>merge|NZ_CP016552|2|348561-349780|CRT,PILER-CR,CRISPRCasFinder,PILER-CR
ATTTTCGTCGAGAGGGTGCGAAATGTGAGGTATAATGACGACCGGCAACGCGATCACTATTGGCAAGTCATAGTTCCCCCTGAGATTATCGCTGTGGTATAATGCAGGATTCGCAGAAGCATGACGTGTCGGAGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTCGATCACTTCCTCGATCTCCGCCAACCGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATGACATAGCCGGAATGCTCGTCGTATTCCACGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATCGTTTTTATTTTGGAGTGATGGCCATGAAAGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATAGAGAACTTTTATGAAAAATTAATGTTAGCGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATCATCGCACCAGACATGTCGCCGCGAATGAAGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTCATCGATCATCACCCATCTCTTCAACCTTGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTTCGCTGTTTATTCCTTTTCATCAAGCTTGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTCATCAGACCCCGAGCCACTGCGAATAAGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATATGAAAAAAGAGGGACAAATGCCCTCTAGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATACAGCGAATGAAGGGTGATCTGTATGATTGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATAAAGGGAAATCGTAAGTATCGTAATCAGCGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATGTGTTGTCGAACCAACAGACGCATCGATTCGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTTCACCTTGAAAGGGGCTTGTTGCTTTTAAGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTTGTTTAAGCGCCTGGACATTATTGACGCTGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTCGTCTTTCACCCGATCAACAAGAGTTTTAGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATAAGAAAAGCATGTCACCTTCAACGTATGCAGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT

>NZ_CP016552|2|1|348561-349780|CRT
ATTTTCGTCGAGAGGGTGCGAAATGTGAGGTATAAT	GACGACCGGCAACGCGATCACTATTGGCAAG
TCATAGTTCCCCCTGAGATTATCGCTGTGGTATAAT	GCAGGATTCGCAGAAGCATGACGTGTCGGA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCGATCACTTCCTCGATCTCCGCCAACCG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	GACATAGCCGGAATGCTCGTCGTATTCCAC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	CGTTTTTATTTTGGAGTGATGGCCATGAAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AGAGAACTTTTATGAAAAATTAATGTTAGC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	CATCGCACCAGACATGTCGCCGCGAATGAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCATCGATCATCACCCATCTCTTCAACCTT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTCGCTGTTTATTCCTTTTCATCAAGCTT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCATCAGACCCCGAGCCACTGCGAATAAG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	ATGAAAAAAGAGGGACAAATGCCCTCTAG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	ACAGCGAATGAAGGGTGATCTGTATGATTG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAAGGGAAATCGTAAGTATCGTAATCAGC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	GTGTTGTCGAACCAACAGACGCATCGATTC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTCACCTTGAAAGGGGCTTGTTGCTTTTAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTGTTTAAGCGCCTGGACATTATTGACGCT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCGTCTTTCACCCGATCAACAAGAGTTTTA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAGAAAAGCATGTCACCTTCAACGTATGCA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT

>NZ_CP016552|2|2|348627-349124|PILER-CR
GTCATAGTTCCCCCTGAGATTATCGCTGTGGTATAAT	GCAGGATTCGCAGAAGCATGACGTGTCGGA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATT	CGATCACTTCCTCGATCTCCGCCAACCGG
TCATAGTTCCCCTGAGATTATCGCTGTGGTATAATGA	CATAGCCGGAATGCTCGTCGTATTCCACGT
CATAGTTCCCCTGAGATTATCGCTGTGGTATAATCGT	TTTTATTTTGGAGTGATGGCCATGAAAGTC
ATAGTTCCCCTGAGATTATCGCTGTGGTATAATAGAG	AACTTTTATGAAAAATTAATGTTAGCGTCA
TAGTTCCCCTGAGATTATCGCTGTGGTATAATCATCG	CACCAGACATGTCGCCGCGAATGAAGTCAT
AGTTCCCCTGAGATTATCGCTGTGGTATAATTCATCG	ATCATCACCCATCTCTTCAACCTTGTCATA
GTTCCCCTGAGATTATCGCTGTGGTATAATTTCGCTGTTTATTCCTTTTCATCAAGCTTGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTCATCAGACCCCGAGCCACTGCGAATAAGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATATGAAAAAAGAGGGACAAATGCCCTCTAGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	ACAGCGAATGAAGGGTGATCTGTATGATTG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAAGGGAAATCGTAAGTATCGTAATCAGC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	GTGTTGTCGAACCAACAGACGCATCGATTC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTCACCTTGAAAGGGGCTTGTTGCTTTTAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTGTTTAAGCGCCTGGACATTATTGACGCT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCGTCTTTCACCCGATCAACAAGAGTTTTA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAGAAAAGCATGTCACCTTCAACGTATGCA


>NZ_CP016552|2|2|348628-349780|CRISPRCasFinder
TCATAGTTCCCCCTGAGATTATCGCTGTGGTATAAT	GCAGGATTCGCAGAAGCATGACGTGTCGGA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCGATCACTTCCTCGATCTCCGCCAACCG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	GACATAGCCGGAATGCTCGTCGTATTCCAC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	CGTTTTTATTTTGGAGTGATGGCCATGAAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AGAGAACTTTTATGAAAAATTAATGTTAGC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	CATCGCACCAGACATGTCGCCGCGAATGAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCATCGATCATCACCCATCTCTTCAACCTT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTCGCTGTTTATTCCTTTTCATCAAGCTT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCATCAGACCCCGAGCCACTGCGAATAAG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	ATGAAAAAAGAGGGACAAATGCCCTCTAG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	ACAGCGAATGAAGGGTGATCTGTATGATTG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAAGGGAAATCGTAAGTATCGTAATCAGC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	GTGTTGTCGAACCAACAGACGCATCGATTC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTCACCTTGAAAGGGGCTTGTTGCTTTTAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTGTTTAAGCGCCTGGACATTATTGACGCT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCGTCTTTCACCCGATCAACAAGAGTTTTA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAGAAAAGCATGTCACCTTCAACGTATGCA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT

>NZ_CP016552|2|3|349284-349780|PILER-CR
	GCAGGATTCGCAGAAGCATGACGTGTCGGA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATT	CGATCACTTCCTCGATCTCCGCCAACCGG
TCATAGTTCCCCTGAGATTATCGCTGTGGTATAATGA	CATAGCCGGAATGCTCGTCGTATTCCACGT
CATAGTTCCCCTGAGATTATCGCTGTGGTATAATCGT	TTTTATTTTGGAGTGATGGCCATGAAAGTC
ATAGTTCCCCTGAGATTATCGCTGTGGTATAATAGAG	AACTTTTATGAAAAATTAATGTTAGCGTCA
TAGTTCCCCTGAGATTATCGCTGTGGTATAATCATCG	CACCAGACATGTCGCCGCGAATGAAGTCAT
AGTTCCCCTGAGATTATCGCTGTGGTATAATTCATCG	ATCATCACCCATCTCTTCAACCTTGTCATA
GTTCCCCTGAGATTATCGCTGTGGTATAATTTCGCTGTTTATTCCTTTTCATCAAGCTTGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATTCATCAGACCCCGAGCCACTGCGAATAAGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAATATGAAAAAAGAGGGACAAATGCCCTCTAGGTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	ACAGCGAATGAAGGGTGATCTGTATGATTG
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAAGGGAAATCGTAAGTATCGTAATCAGC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	GTGTTGTCGAACCAACAGACGCATCGATTC
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTCACCTTGAAAGGGGCTTGTTGCTTTTAA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TTGTTTAAGCGCCTGGACATTATTGACGCT
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	TCGTCTTTCACCCGATCAACAAGAGTTTTA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT	AAGAAAAGCATGTCACCTTCAACGTATGCA
GTCATAGTTCCCCTGAGATTATCGCTGTGGTATAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	unknown	unknown	gnl\|CDD\|239071
NZ_CP016552.1\|WP_095858794.1\|335498_336695_+\|TIGR02678-family-protein	unknown	unknown	gnl\|CDD\|274254
NZ_CP016552.1\|WP_011229827.1\|358977_359202_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858801.1\|355451_355661_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376019
NZ_CP016552.1\|WP_095858795.1\|336654_340776_+\|TIGR02680-family-protein	unknown	unknown	gnl\|CDD\|274256
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP016552.1\|WP_095858793.1\|334005_335496_+\|TIGR02677-family-protein	unknown	unknown	gnl\|CDD\|131724
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP016552.1\|WP_095858791.1\|328138_329626_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225962
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	unknown	unknown	gnl\|CDD\|274255
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	unknown	unknown	gnl\|CDD\|237372
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|225943
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP016552.1\|WP_095858792.1\|329644_330145_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225937
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	gnl\|CDD\|239071	cd02253, DmpA, L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active heterodimeric form. The cleavage results in two polypeptide chains, with one chain containing an N-terminal nucleophile. This group represents one of the rare aminopeptidases that are not metalloenzymes. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	4.48423e-175
NZ_CP016552.1\|WP_095858794.1\|335498_336695_+\|TIGR02678-family-protein	gnl\|CDD\|274254	TIGR02678, hypothetical_protein, TIGR02678 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	1.30358e-151
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	gnl\|CDD\|376019	pfam18593, CdiI_2, CdiI immunity protein. Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Structure analysis of CdiI immunity protein from Yersinia kristensenii shows that it is composed of eight alpha-helices packed together to form a nearly spherical structure with weak structural homology to a putative TetR family transcriptional repressor. The CdiI protein fits into the curved cavity of the CdiA-CTYkris toxin domain where it most likely neutralizes toxin activity by blocking access to RNA substrates. This domain is mostly found in gammaproteobacteria.	0.000887762
NZ_CP016552.1\|WP_095858795.1\|336654_340776_+\|TIGR02680-family-protein	gnl\|CDD\|274256	TIGR02680, conserved_hypothetical_protein, TIGR02680 family protein. Members of this protein family belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). Proteins in this family average over 1400 amino acids in length. [Hypothetical proteins, Conserved].	0
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.31022e-42
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.29636e-10
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19707e-110
NZ_CP016552.1\|WP_095858793.1\|334005_335496_+\|TIGR02677-family-protein	gnl\|CDD\|131724	TIGR02677, conserved_hypothetical_protein, TIGR02677 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	0
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP016552.1\|WP_095858791.1\|328138_329626_-\|PH-domain-containing-protein	gnl\|CDD\|225962	COG3428, COG3428, Predicted membrane protein [Function unknown].	1.86702e-55
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	gnl\|CDD\|274255	TIGR02679, conserved_hypothetical_protein, TIGR02679 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	2.0043e-132
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.05989e-06
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	gnl\|CDD\|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	1.14699e-06
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	gnl\|CDD\|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	1.80502e-24
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.47396e-99
NZ_CP016552.1\|WP_095858792.1\|329644_330145_-\|PH-domain-containing-protein	gnl\|CDD\|225937	COG3402, COG3402, Uncharacterized conserved protein [Function unknown].	1.96866e-29
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.50141e-44
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.53622e-36

>NZ_CP016552.1|WP_095858799.1|345335_346619_-|peptidoglycan-binding-protein
MYVVDASGRHYYPSNYTNYLWNGQTLRKGDRGAYVKTLQSWLHKAGFNPGAIDGIYGANTEKAVKEFQKKVGITADGIAGKQTYNALQSYLRTQTSTSKSTSSTSNNSNDWTGQTLRKGSQGESVKDLQIMLNYAGYNVKVDGIYGSETEKAVRSFQKSVGISVDGIAGAQTYKSLNSYISSKANKGVTIDISKEAQRLQKEAEEKKKQELAKALIDVATDFVPVVGQFKDAYNLVNTLFNPNATAKEVGLALFAFIPAVGDLKNIGKAIDAIKSTVKKGTDKIDDAAIDFISKKIREINASDLLLYSEKAGGHTISEHISLSDTQMVKRAAQQKIDVTSYTNQNTAIKVIKSALSQNASKIAEWLLDPNSRDRLNLNQEMGYAIGKGYKSGGTALKTNLDTAFIQLKKDSKSKYGFIIVTSYPKYK
>NZ_CP016552.1|WP_095858798.1|345023_345323_-|hypothetical-protein
MDIRKEFENLQYFFDSYYNQTFYDAKLEDKFLEFLNDEPKWVSKALKEEIKKLEQIYNNKDINTWAKIEELVHENSMRYFPYEDGKKFIEIANKFLENV
>NZ_CP016552.1|WP_015374552.1|342855_343901_-|IS630-like-element-ISBs2-family-transposase
MMPNHKDEIEKLSTAMKEAKSKRAYERYQAIYLHLQGYTKGEIATIIGRSKKTIYNYIHAYAQRGLDGLEMKYSPGAPRRLTPEQEKELALIIEHQLPVDVGFEAKYNWTLAIIAELIQQKWGPTYTLRGTSDILHRLGLSYTKPTYTLANADEEKQKEFVEITFPEVKKLVDGNIAHVLFQDESMIRDYQAIQKTWFVKGKQRIIPTFGKHQGLKLIGTLNYETGEVFCIEEERYDAETFLRFLQLVLERYPTGKIVMILDNARIHHAKLIQPFLKEHEDRLELVFLPPYSPQLNLIEGLWKWLKSDVIYNVFYSSVQEIRKNVQAFIQRINQKPEQTIDRLCVQL
>NZ_CP016552.1|WP_095858797.1|342060_342438_+|transposase
MLARLELDEAKQRLLFGFFETYLRRSEEEEAKRRHEVSQMETKEAKQVMELIVSYEQRGMEKGIEKGIEQGVKQGIKQGIKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858796.1|340772_341993_+|TIGR02679-family-protein
MSTAKEAAAFFRSEPGFRRLFIEMKHKYESLGRVGGAVSLEAFTDEEREAVAAFFGKDVSRVSLIAFEKQLGQTRFAGVGLVELLEQYFGAPLVSNKERRQAEEEERDRFFARLTEEHHWVESVRPQRFVQTAYETDRRSLEEAIRLVSAALGRLPLPSYMRLPLFAQQVAGDPHAFDLSTLPGRLLLSALQATVPGDWDMASVESVNELLQSVGLLREDILNFVTCANILAETEGGPHPVFSAASETNTALNMPLRDVLSLVRARPAHGGTVYIVENAGVFSTLLDTRAPLVSTNGQMNLATMKLLDLLASSGAKLYYSGDFDPEGLAMAERLQERYGQAVTLWRFSVEDYRAANPVVDLTPERLAKLASVTSTPLQPLKEEMAETKKAGYQEAIIGRLTGDING
>NZ_CP016552.1|WP_095858795.1|336654_340776_+|TIGR02680-family-protein
MANPWVLHRAGLINFWYYDEQYFHFADGKLLLRGSNGAGKSVTMQSLIPVLLDGKKTPDRLDPFGSRARRMEDYLLGEKDVVNRDERTGYLFLEYKRKASDQYVTTGIGLRAKRQKSLDFWGFVIFDNRRIGHHLTLYKKEKTGEKIPLTKRELAALLGAGGTVVDTQKEYMELVNKHVFRFESLESFQELIELLIQLRSPKLSKDFKPTVIYEILESSLPPLTDDELRHLSDTIENMDQAKQQLEQLERDERALKRLCDQYRLYNEYMIAEKAAEYVKAVKQAEQLAAEQQRLHDEEERARTMLDELEESITRLGREEDVLRAREIDLAGHEVFQQAEKYEQLKAEQQRLEERRKRHEQTIAEKERQERQHRRRLDEAEARLDDLERKLEDELEQLRMDADEGSFSLHETNEGDFHRHRQKEQEFLFAAWKQEADRHIERLEGLARLWRRHDEVKQRYEEASSEAGERQREMDEWRHQQRKWEELLEQEKERFEQAVLAWIGQGDVDISEADIQSFLQQMDALYEQYSLDDLKRPFVQAYYDAVGKKKDEKWRLEHDIRLLEEKRAEREAELRRWREQRDPEPERDEQTTAARLALEEKGIPFVPLYAAVEFVDDVPDDVRERIESALSHAGLLDALITAREIDVACDRVLIPKPVHMAHTLADYLRPDANAPVSMERIDEVLRSIVITDADQEGGMTIDETGRYSLGLVRGHAPRRSKAMFIGRAARERWRLENIAALEAEIAAVGQEIDRLRGAHEDVEAAIQALADWLASFPSDRDVRTAFDEAQEARRQAESKEREWKRQEEKAALLAREWKQIKQQLRDESAELDLAFTLDGCEQAMLAMKSYVRHLHELEVLYRETRHTEAVIAQQREQLAVLEAEIDEAKGERNRLRDETERLALRIAEMERTLAQMGADDIRAEIARIQERLASLRREIPRLVNERARTEQQLMRLVEEREKGAQREEFARELAAMWEKSFAREAALGLVDLDRSRSLLEQAKEAKQRYEAVLKETRSSLLARLNTVFFQESSNLTEYRASFEPLEEQTKPEWTAAAPDDEMAMKAADWREKQERHVIYLDYKGERATPFAVLAEVERDIVLQHEYMKEQDRELYEDVILKSVGRILRSRIQRAERWVNDMNKLMGGLDTSSGLVLSIQWKPKTAETEAELDTKELVRLLRLDPRLLREEDLQRVTNHFRSKIARARELLEERGQGSTLHQIIKEVLDYRKWFSFTLYYEKTNEPKRELTNHRFYQFSGGEKAMAMYIPLFAAAYSRYQEAGDDAPYIISLDEAFAGVDENNIRNLFGLVEQLGFNYIMNSQALWGDYDTVPALSICELVRPRNASFVTVIHYRWNGRVKQLMVNDKEWETIET
>NZ_CP016552.1|WP_095858794.1|335498_336695_+|TIGR02678-family-protein
METAFDDKAKEALAALFEQFWIIRDQEPDLYQLVREREHVLKRYVEEKFGYRLIVHRYFAKLEKIPADPEPWMGIESFQEPLDYALFCCLMAYLEGKAVEEKFLLSDVCEEIRAMYPGDLPVDWTNYAHRRALIRVLKTAEQIGLVRRMDGEIEAFAQHAEEEALYEVPVLARYFMRTHPKDLLRYESIEELMAEEWKASPQDYRRHRLYRKLFLSPAVHRTEGDEQDFYYLRNFRHRLRDDIEAHTPFRYELYKNAAMLTLPERQAPYTTFPDQKGTSEIILHFSALVRERLGEYPPDEYGRIRLTPEQFSAWLADCRRRYGAGWGKTYRDMSAAELVREVLAALCEWRMADVEHDTGMIVLYPLLGRVAGRYPDDFDAKEGGEHGESMGASSCGAD
>NZ_CP016552.1|WP_095858793.1|334005_335496_+|TIGR02677-family-protein
MDATWLKPIVETKYLSTENAHRYRAILRYFYIQHERMRQYLFPEEVYAFLKQHEEFADYTEDDLQQDLDQLVKWNNLIARQETSHVRTIEEFKKKRFRYQCSPYTVEIERMIRTLEQLGDSFGGSLEKTRFDRLYASLSRIEAIIASGFQEQRDEMYQVWEETFDYFKKIIQNSADYMAYLHSENVEERMTSESFLVYKEQFTAYLRDFIVALQKTSMQIEQLLEDLPEEGVRQFIGHVVDYERSIPRFADAPPPRAVQIEEKWETWRSLCEWFLGRNGRESELSFLQYQTNEAIRRLTRVVQRLGERHHHFRSRKGDYLHLARWFSRLESIEEAHCLSAVVFGCFHTKHLVADAEATDNIYRDVWDEPPAEWVTKPRVRHYGEKKKPQAIEDKEREKEEARLRYLEEKAREEAELKQFVTDGKIVLADLPEVTPYVRKTLLGWIAKAMGREGQAMKTENGWVVNVVNKEGTICLRAEDGELVMPNYEIHVLSGGE
>NZ_CP016552.1|WP_095858792.1|329644_330145_-|PH-domain-containing-protein
MTQTIKEPKQQISPNAVKVWRISDAITYFITLCILTVLLYLQHYYDWKNWVGVILYFIVILVIISSIVEIIFVPIYRQKTWRYDVDEKYIQLKYGGVFMKTHLIIPMTKVQYVNTIQGPLLRKFGLSTIKIGTMASVHEIPAIPEKKATELREKIAYLAGVNESDE
>NZ_CP016552.1|WP_095858791.1|328138_329626_-|PH-domain-containing-protein
MNNEITNDQARRIHPLWIFFSIGKSIKELVLFVITFIIYIRSDSDSILIKITGIAIVFYLIYKIVSILLEWFHFKYLFTNKELYIHEGRFIKEKRYIPLERIQGIKRTTPFFHRLFGLTSLILDTGASGNKSTIKLGMITCEEAERIQKHLSHISSFHKDKGVSEQNVQTSKEIAPELSSRKKYYEMTSKEIFVASVTSLSLLIFLSVLYTIYDNVSDFFSIDSYIDTVISFFQKSWLLTFLGIVALLMLSMAYGWARTYVIYRNFEVTGDNQRIYIRKGLFNQTEFSIPKEKVEAIILNTKLLKKILGIVEVKIISTGDGDENEMKTANILFPFIDKRRALSLIPQIFPAFHVETEMVNLPRSAIFVKLVRTSYIWIIAAAINFYFWPNFWYISVALFVLINTSQLLSGLYSCYNLCGPFIQIQTGSFSTKLFITTRMKIEELKVTESLLQRMFGLASLEISTRSKSIQVSKISDIPKDMAIRYYQWYANKENH
>NZ_CP016552.1|WP_033016933.1|349881_350190_-|CRISPR-associated-endonuclease-Cas2
MRLLVFFDLPVVTNREKREYRRFRTFLLNEGYDMLQFSVYSRVCHGHEATDKHLARLKRNLPPRGSIRAMVVTEKQYAKMQLLLGEPTAQEKKVTSTQLTLF
>NZ_CP016552.1|WP_050368140.1|350194_351094_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRHLLIRKPGKLSVRYNQLVIEQEEKVSIPLEDICSIIIEEQAVSVTAAALSKMAEHNITLFTCDQKRLPNGVLQPFQKHSRQVGVLHMQYAYSKPFKKRIWQRIVIQKLINQGKCLEFLNKEGADDLYRISKTVDSGDSNNREAYGAKKYFQYLFGSEFTRRSDSVVNASLNYGYAIMRGLVARSLVGYGFLPCLGIYHDNELNKFNLADDFMEVLRPLVDLYVAQHIQPDDEFSPSIRADLYNLVNMDILVNGEKLTVVNAVEEMTKSFVTASRSQDPSLLKLPELLPLQLHVYE
>NZ_CP016552.1|WP_095858800.1|351023_354287_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MRYKIGLDIGITSVGWAVINLDIPRIEDLGVRIFDRAENPQTGESLALPRRLARSARRRLRRRKHRLERIRRLVIREGILTKEELDKLFEEKHEIDVWQLRVEALDRKLNNDELARVLLHLAKRRGFKSNRKSERSNKENSTMLKHIEENRAILSGYRTVGEMIVKDPKFALHKRNKGENYTNTIARDDLEHEIRLIFSKQREFGNMSCTEKFENEYITIWASQRPVASKDDIEKKVGFCTFEPKEKRAPKATYTFQSFIAWEHINKLRLISPSGTRGLTDEERRLLYEQAFQKNKITYHDIWTLLRLPDDTYFKGIVYDRGESRKQNENIRFLELDAYHQIRKAVDKVYGKGKSSSFLPIDFDTFGYALTLFKDDADIRSYLQNEYEQNGKRMPNLANKVYDNELIEELLNLSFTKFGHLSLKALRSILPYMEQGEVYSSACERAGYTFTGPKKKQKTMLLPNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARDLSQTFDERRKTKKEQDENRKKNETAIRQLMEYGLTLNPTGHDIVKFKLWSEQNGRCAYSLQPIEIERLLEPGYVEVDHVIPYSRSLDDSYTNKVLVLTRENREKGNRIPAEYLGVGTERWQQFETFVLTNKQFSKKKRDRLLRLHYDENEETEFKNRNLNDTRYISRFFANFIREHLKFAESDDKQKVYTVNGRVTSHLRSRWDFNKNREESDLHHAVDAAIVACTTPSDIAKVTAFYQRREQNKELAKKTEPHFPQPWPHFADELRARLSKHPKESIKALNLGNYDDQKLESLQPVFVSRMPKRSVTGAAHQETLRRYIGIDERSGKIQTVVKTKLSEIKLDASGHFPMYGKESDPRTYEAIRQRLLEHNNDPKKAFQEPLYKPKKNGEPGPIIRTVKIIDTKNQVIPLNDGKTVAYNSNIVRVDVFEKDGKYYCVPVYTMDIMKGILPNKAIEPNKPYSEWKEMTEDYTFRFSLYPNDLIRIELPREKTVKTTTGEEINVKDVFVYYKTIDSATGGLELISHDNRFSLRGVGSRTLKRFEKYQVDVLGNIYKVRGEKRVGLASSAHSKTGETIRPLQSTRD
>NZ_CP016552.1|WP_095860176.1|354681_355047_+|transposase
MLVRLELDEAKQRLLFGFFETYLRLSEEEEAKPRHEVSQMETKEAKRVMELIVSYEQRGLEKGIQQGIEQGIKQGMKQGRQEGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858801.1|355451_355661_+|hypothetical-protein
MITIYDLIGYIQNMDNMDKLDEIISRWYFQTPVWTSQVKEEVKKAVVEILQLGEPKVYQFFVDMYGLKM
>NZ_CP016552.1|WP_095858802.1|355827_356712_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIRTFFEEFLLLFFPDMHEHIDFHHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVETQGYVQPTFAERMFLYFSRLYETYRTRIVPIAVFHYDSLREEPSVFSMEFPFGEVLQFRFFPVALRKKQWREYIRHDNPVAAALLSQMGYTEREKVELKKEFLRMQVRLELDEARQRLLLGFFETYVKLTEEEEQQLQSEVKAMETKEREKVLELIISYEQKGKKEGLEEGVKRGLEQGMKQGMKRLIETMAQKGMTAAEIARLVDLSEEEVRSLLSE
>NZ_CP016552.1|WP_042382835.1|357744_358491_+|CRISPR-associated-endoribonuclease-Cas6
MRLTITMSGRQGPVSLPLHYQHLLQGMLYRSLENEQLAAFLHDKGFRHGKRSFKLFTFSRLFGTHQVDRGKKAIRFLDDFQWHIDTVLPELTQQLGQRFLLQREIELYGQLIEVKSVKMENIDIRENEIDIVMLSPLTVYSTYETFDGRKKTQFFDPDDEVFPHLIELNFRHKYEAYYGVPPTERLLIEPIHVHHRHRVVTMFKNMYITGWLGYYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLKSE
>NZ_CP016552.1|WP_011229827.1|358977_359202_-|hypothetical-protein
MQQRQRKAVNNHAWWINGAIQKKQMPKRSPCAKQKSGFLQSKRRKNEQPKQNEAVDRGSAAIRFLQTEDVHTMA
>NZ_CP016552.1|WP_095858803.1|359338_360385_+|P1-family-peptidase
MRRKLRDLGFSIGTLPVGRRNQITDVPGVRVGHVTIREERDERTVVRTGVTAVLPHGGNWFLEKVPAACFVLNGFGKTAGLVQVEELGTIESPIMLTNTFSVGAVWQGTLEYMLEATPEIGDVTGSVNIVVGECNDSYLNTARALSVTKEHAKEAIAAARVEMEEGAIGAGTGMMCFGWKGGVGSSSRVVSRGYTVGALVVSNFGRREELRFVPYMPPSFDERDVPPGSIMMIVATDAPLDARQLKRLAKRAAVGLGRTGSCVHHGSGDIVIAFSNAYTIPHFSDSALQSVPPLIRDDAPLMNELFQAAIEATEEAIWNSLTMAETTTGRNGRIGEAIPYALLRRMGE
>NZ_CP016552.1|WP_095858804.1|360445_361678_-|MFS-transporter
MNWKRSVRVLWLCNFMVSAGMTMVIPFLSLLLWEMGVTEHHSLSVWTGLVFSATFLSAAIMAPIWGMFADKYGQRANLIRAGIGMGLITGCMAFAASPMALLALRFLVGFFSGFITVSFSYLARVVPKDHSGEALGTLQTGSIAGNIIGPLIGGALSDWFGFRPVFLMTGFCILATLLPVVFWLDKDPVAPQTQERHASFKEVFAHRPLVILFVATFLVQIAVLGVNSMMTIFVQSLVGDSRNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQEKTLPILLVLSGLFALPQVWTDHLYELYVWRFLQGLVVGGVWPALQALINAQCPRRIQGRVFGVTASSRFLGNLAGPTAAGAIAGFASISAIFALSGLLLIATGALVGSTTRDRAWREDMKEKIAAWAHRLHIRH

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Crispr_ID: NZ_CP016552_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_4

355663-355760

TypeII

Consensus_repeat	Method
GTTTTTATCGCACCTATGAGGGATTGAAACT	CRISPRCasFinder

1 spacers

cas9,cas1,cas2,cas6

The CRISPR arrays of NZ_CP016552_4

>merge|NZ_CP016552|4|355663-355760|CRISPRCasFinder
GTTTTTATCGTACCTATAAAGGGATTGAAACGTCATCCCGGTCGTGACAATTGGAGTTCCTTCTGCCGTTTTTATCGTACCTATGACGAATTTCTCAC

>NZ_CP016552|4|4|355663-355760|CRISPRCasFinder
GTTTTTATCGTACCTATAAAGGGATTGAAAC	GTCATCCCGGTCGTGACAATTGGAGTTCCTTCTGCC
GTTTTTATCGTACCTATGACGAATTTCTCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_095858805.1\|361876_362530_-\|PspA/IM30-family-protein	unknown	unknown	gnl\|CDD\|224755
NZ_CP016552.1\|WP_095858807.1\|363739_366049_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NZ_CP016552.1\|WP_011229827.1\|358977_359202_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376019
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	unknown	unknown	gnl\|CDD\|239071
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP016552.1\|WP_033011731.1\|366124_366694_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	unknown	unknown	gnl\|CDD\|274255
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	unknown	unknown	gnl\|CDD\|237372
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|225943
NZ_CP016552.1\|WP_095858801.1\|355451_355661_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858806.1\|362489_363014_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_033024617.1\|363194_363542_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_095858805.1\|361876_362530_-\|PspA/IM30-family-protein	gnl\|CDD\|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	7.13874e-22
NZ_CP016552.1\|WP_095858807.1\|363739_366049_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	7.50419e-158
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	gnl\|CDD\|376019	pfam18593, CdiI_2, CdiI immunity protein. Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Structure analysis of CdiI immunity protein from Yersinia kristensenii shows that it is composed of eight alpha-helices packed together to form a nearly spherical structure with weak structural homology to a putative TetR family transcriptional repressor. The CdiI protein fits into the curved cavity of the CdiA-CTYkris toxin domain where it most likely neutralizes toxin activity by blocking access to RNA substrates. This domain is mostly found in gammaproteobacteria.	0.000887762
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	gnl\|CDD\|239071	cd02253, DmpA, L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active heterodimeric form. The cleavage results in two polypeptide chains, with one chain containing an N-terminal nucleophile. This group represents one of the rare aminopeptidases that are not metalloenzymes. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	4.48423e-175
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.31022e-42
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.29636e-10
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19707e-110
NZ_CP016552.1\|WP_033011731.1\|366124_366694_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.99354e-16
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	gnl\|CDD\|274255	TIGR02679, conserved_hypothetical_protein, TIGR02679 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	2.0043e-132
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.05989e-06
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	gnl\|CDD\|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	1.14699e-06
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	gnl\|CDD\|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	1.80502e-24
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.47396e-99
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.50141e-44
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.53622e-36

>NZ_CP016552.1|WP_095858801.1|355451_355661_+|hypothetical-protein
MITIYDLIGYIQNMDNMDKLDEIISRWYFQTPVWTSQVKEEVKKAVVEILQLGEPKVYQFFVDMYGLKM
>NZ_CP016552.1|WP_095860176.1|354681_355047_+|transposase
MLVRLELDEAKQRLLFGFFETYLRLSEEEEAKPRHEVSQMETKEAKRVMELIVSYEQRGLEKGIQQGIEQGIKQGMKQGRQEGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858800.1|351023_354287_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MRYKIGLDIGITSVGWAVINLDIPRIEDLGVRIFDRAENPQTGESLALPRRLARSARRRLRRRKHRLERIRRLVIREGILTKEELDKLFEEKHEIDVWQLRVEALDRKLNNDELARVLLHLAKRRGFKSNRKSERSNKENSTMLKHIEENRAILSGYRTVGEMIVKDPKFALHKRNKGENYTNTIARDDLEHEIRLIFSKQREFGNMSCTEKFENEYITIWASQRPVASKDDIEKKVGFCTFEPKEKRAPKATYTFQSFIAWEHINKLRLISPSGTRGLTDEERRLLYEQAFQKNKITYHDIWTLLRLPDDTYFKGIVYDRGESRKQNENIRFLELDAYHQIRKAVDKVYGKGKSSSFLPIDFDTFGYALTLFKDDADIRSYLQNEYEQNGKRMPNLANKVYDNELIEELLNLSFTKFGHLSLKALRSILPYMEQGEVYSSACERAGYTFTGPKKKQKTMLLPNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARDLSQTFDERRKTKKEQDENRKKNETAIRQLMEYGLTLNPTGHDIVKFKLWSEQNGRCAYSLQPIEIERLLEPGYVEVDHVIPYSRSLDDSYTNKVLVLTRENREKGNRIPAEYLGVGTERWQQFETFVLTNKQFSKKKRDRLLRLHYDENEETEFKNRNLNDTRYISRFFANFIREHLKFAESDDKQKVYTVNGRVTSHLRSRWDFNKNREESDLHHAVDAAIVACTTPSDIAKVTAFYQRREQNKELAKKTEPHFPQPWPHFADELRARLSKHPKESIKALNLGNYDDQKLESLQPVFVSRMPKRSVTGAAHQETLRRYIGIDERSGKIQTVVKTKLSEIKLDASGHFPMYGKESDPRTYEAIRQRLLEHNNDPKKAFQEPLYKPKKNGEPGPIIRTVKIIDTKNQVIPLNDGKTVAYNSNIVRVDVFEKDGKYYCVPVYTMDIMKGILPNKAIEPNKPYSEWKEMTEDYTFRFSLYPNDLIRIELPREKTVKTTTGEEINVKDVFVYYKTIDSATGGLELISHDNRFSLRGVGSRTLKRFEKYQVDVLGNIYKVRGEKRVGLASSAHSKTGETIRPLQSTRD
>NZ_CP016552.1|WP_050368140.1|350194_351094_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRHLLIRKPGKLSVRYNQLVIEQEEKVSIPLEDICSIIIEEQAVSVTAAALSKMAEHNITLFTCDQKRLPNGVLQPFQKHSRQVGVLHMQYAYSKPFKKRIWQRIVIQKLINQGKCLEFLNKEGADDLYRISKTVDSGDSNNREAYGAKKYFQYLFGSEFTRRSDSVVNASLNYGYAIMRGLVARSLVGYGFLPCLGIYHDNELNKFNLADDFMEVLRPLVDLYVAQHIQPDDEFSPSIRADLYNLVNMDILVNGEKLTVVNAVEEMTKSFVTASRSQDPSLLKLPELLPLQLHVYE
>NZ_CP016552.1|WP_033016933.1|349881_350190_-|CRISPR-associated-endonuclease-Cas2
MRLLVFFDLPVVTNREKREYRRFRTFLLNEGYDMLQFSVYSRVCHGHEATDKHLARLKRNLPPRGSIRAMVVTEKQYAKMQLLLGEPTAQEKKVTSTQLTLF
>NZ_CP016552.1|WP_095858799.1|345335_346619_-|peptidoglycan-binding-protein
MYVVDASGRHYYPSNYTNYLWNGQTLRKGDRGAYVKTLQSWLHKAGFNPGAIDGIYGANTEKAVKEFQKKVGITADGIAGKQTYNALQSYLRTQTSTSKSTSSTSNNSNDWTGQTLRKGSQGESVKDLQIMLNYAGYNVKVDGIYGSETEKAVRSFQKSVGISVDGIAGAQTYKSLNSYISSKANKGVTIDISKEAQRLQKEAEEKKKQELAKALIDVATDFVPVVGQFKDAYNLVNTLFNPNATAKEVGLALFAFIPAVGDLKNIGKAIDAIKSTVKKGTDKIDDAAIDFISKKIREINASDLLLYSEKAGGHTISEHISLSDTQMVKRAAQQKIDVTSYTNQNTAIKVIKSALSQNASKIAEWLLDPNSRDRLNLNQEMGYAIGKGYKSGGTALKTNLDTAFIQLKKDSKSKYGFIIVTSYPKYK
>NZ_CP016552.1|WP_095858798.1|345023_345323_-|hypothetical-protein
MDIRKEFENLQYFFDSYYNQTFYDAKLEDKFLEFLNDEPKWVSKALKEEIKKLEQIYNNKDINTWAKIEELVHENSMRYFPYEDGKKFIEIANKFLENV
>NZ_CP016552.1|WP_015374552.1|342855_343901_-|IS630-like-element-ISBs2-family-transposase
MMPNHKDEIEKLSTAMKEAKSKRAYERYQAIYLHLQGYTKGEIATIIGRSKKTIYNYIHAYAQRGLDGLEMKYSPGAPRRLTPEQEKELALIIEHQLPVDVGFEAKYNWTLAIIAELIQQKWGPTYTLRGTSDILHRLGLSYTKPTYTLANADEEKQKEFVEITFPEVKKLVDGNIAHVLFQDESMIRDYQAIQKTWFVKGKQRIIPTFGKHQGLKLIGTLNYETGEVFCIEEERYDAETFLRFLQLVLERYPTGKIVMILDNARIHHAKLIQPFLKEHEDRLELVFLPPYSPQLNLIEGLWKWLKSDVIYNVFYSSVQEIRKNVQAFIQRINQKPEQTIDRLCVQL
>NZ_CP016552.1|WP_095858797.1|342060_342438_+|transposase
MLARLELDEAKQRLLFGFFETYLRRSEEEEAKRRHEVSQMETKEAKQVMELIVSYEQRGMEKGIEKGIEQGVKQGIKQGIKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858796.1|340772_341993_+|TIGR02679-family-protein
MSTAKEAAAFFRSEPGFRRLFIEMKHKYESLGRVGGAVSLEAFTDEEREAVAAFFGKDVSRVSLIAFEKQLGQTRFAGVGLVELLEQYFGAPLVSNKERRQAEEEERDRFFARLTEEHHWVESVRPQRFVQTAYETDRRSLEEAIRLVSAALGRLPLPSYMRLPLFAQQVAGDPHAFDLSTLPGRLLLSALQATVPGDWDMASVESVNELLQSVGLLREDILNFVTCANILAETEGGPHPVFSAASETNTALNMPLRDVLSLVRARPAHGGTVYIVENAGVFSTLLDTRAPLVSTNGQMNLATMKLLDLLASSGAKLYYSGDFDPEGLAMAERLQERYGQAVTLWRFSVEDYRAANPVVDLTPERLAKLASVTSTPLQPLKEEMAETKKAGYQEAIIGRLTGDING
>NZ_CP016552.1|WP_095858802.1|355827_356712_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIRTFFEEFLLLFFPDMHEHIDFHHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVETQGYVQPTFAERMFLYFSRLYETYRTRIVPIAVFHYDSLREEPSVFSMEFPFGEVLQFRFFPVALRKKQWREYIRHDNPVAAALLSQMGYTEREKVELKKEFLRMQVRLELDEARQRLLLGFFETYVKLTEEEEQQLQSEVKAMETKEREKVLELIISYEQKGKKEGLEEGVKRGLEQGMKQGMKRLIETMAQKGMTAAEIARLVDLSEEEVRSLLSE
>NZ_CP016552.1|WP_042382835.1|357744_358491_+|CRISPR-associated-endoribonuclease-Cas6
MRLTITMSGRQGPVSLPLHYQHLLQGMLYRSLENEQLAAFLHDKGFRHGKRSFKLFTFSRLFGTHQVDRGKKAIRFLDDFQWHIDTVLPELTQQLGQRFLLQREIELYGQLIEVKSVKMENIDIRENEIDIVMLSPLTVYSTYETFDGRKKTQFFDPDDEVFPHLIELNFRHKYEAYYGVPPTERLLIEPIHVHHRHRVVTMFKNMYITGWLGYYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLKSE
>NZ_CP016552.1|WP_011229827.1|358977_359202_-|hypothetical-protein
MQQRQRKAVNNHAWWINGAIQKKQMPKRSPCAKQKSGFLQSKRRKNEQPKQNEAVDRGSAAIRFLQTEDVHTMA
>NZ_CP016552.1|WP_095858803.1|359338_360385_+|P1-family-peptidase
MRRKLRDLGFSIGTLPVGRRNQITDVPGVRVGHVTIREERDERTVVRTGVTAVLPHGGNWFLEKVPAACFVLNGFGKTAGLVQVEELGTIESPIMLTNTFSVGAVWQGTLEYMLEATPEIGDVTGSVNIVVGECNDSYLNTARALSVTKEHAKEAIAAARVEMEEGAIGAGTGMMCFGWKGGVGSSSRVVSRGYTVGALVVSNFGRREELRFVPYMPPSFDERDVPPGSIMMIVATDAPLDARQLKRLAKRAAVGLGRTGSCVHHGSGDIVIAFSNAYTIPHFSDSALQSVPPLIRDDAPLMNELFQAAIEATEEAIWNSLTMAETTTGRNGRIGEAIPYALLRRMGE
>NZ_CP016552.1|WP_095858804.1|360445_361678_-|MFS-transporter
MNWKRSVRVLWLCNFMVSAGMTMVIPFLSLLLWEMGVTEHHSLSVWTGLVFSATFLSAAIMAPIWGMFADKYGQRANLIRAGIGMGLITGCMAFAASPMALLALRFLVGFFSGFITVSFSYLARVVPKDHSGEALGTLQTGSIAGNIIGPLIGGALSDWFGFRPVFLMTGFCILATLLPVVFWLDKDPVAPQTQERHASFKEVFAHRPLVILFVATFLVQIAVLGVNSMMTIFVQSLVGDSRNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQEKTLPILLVLSGLFALPQVWTDHLYELYVWRFLQGLVVGGVWPALQALINAQCPRRIQGRVFGVTASSRFLGNLAGPTAAGAIAGFASISAIFALSGLLLIATGALVGSTTRDRAWREDMKEKIAAWAHRLHIRH
>NZ_CP016552.1|WP_095858805.1|361876_362530_-|PspA/IM30-family-protein
MGIFRRMKTIVLAEVNEQIDRWEDPVAMTKQYLRELEEQLERGRQALAQQWVAERRYETLIAQAEATIEKRSRQAKLALERNEEAVAKLALRDKLLYEKKLEAYKQQYDAIKAKTAEVANRLNQLRERYDELAAKQLELATRVNAAQALKQIDSALASFSADEALRGFARMEERVIALEAEAAAARFGTNAVLSPVPFDEEVERELAKWKEAQANNA
>NZ_CP016552.1|WP_095858806.1|362489_363014_-|hypothetical-protein
MKKARAVFLLALVALAGVSLFHVLAPHEVMAHGRPGAPFDGMPGGFGHPHREFIMEQRGGWMMPMLFLKWLIPLLLAAAGAVWLAAARSKRWIGWVLVALGIAALLPKWVLLLLALAAVYALGRRQARKPSAVEALMPAAPSVSADWLDEWEKTIQKEAQTNGHFSPNEDDRSR
>NZ_CP016552.1|WP_033024617.1|363194_363542_+|hypothetical-protein
MVRSYGVDVGGALLVLWFSFLFPTFYVGYYAYGSFLGFAIGSLIVGLARIRWHPQARFGGTLIGSFLIIAVSVLIIRLFPIEIRDVGDLVMQYINAVVNALIYLAFSTPSTCCIA
>NZ_CP016552.1|WP_095858807.1|363739_366049_-|YhgE/Pip-domain-containing-protein
MHAFQLWLKEWKAILTNRKVLIPVIAVLFIPLLYSGMFLWAFWDPYNHLDELPVAVVNQDKGAMLDGKEIHLGKDLVEKLKENKQFDWHFVTEHEGEKGLKEQKYYMLIQIPDDFSRNATTLQDDHPKKLELIYKPNEGFNFLSAQIGQTAVEKIKNEVANAITETYAESMFDTIQTVADGLTKASDGAARLHDGLSQAQDGTNRLYDGMKKAQDGSETLYHHLATLAEKSVSFTDGLHQAASGSLQVQTGSEALYNGMKQMTAGQEKLLSGAKQAQQGAANLASGTRRVYEGMQTLDARMPRLLQGSEQLSGGAEKLASSLAQWQQGAARVQTGATQVTGGLEQLAAQLDALIAQTPDPTQKAVYERLKENVEKLSFGSKQVENGLAQLNSGAQSLHSGASSLHEGAQKLHEGHIALDRGVDELLAGQQQLVNGADALANGQEQLVSGMKTMYDKMQEAAQGASQLAHGSGTLSSGLQTLAQGADQLQDGTRRLANGSQQVADGTKELTNGTKHLQDGVNQLTDGSKELANKLKEGAEQASDVKANEAVYDMFAQPVNLHKEEINKVPNYGTGFTPYFLSLGLFVGALLLSIVFPLREPAEIPRSPLHWFLAKFGVLIGIGILQALLADVVLLVGLDLHVKSVPLFIVFSIVTSITFLSVIQFLVTVFGDPGRFIAIVVLILQLTTSAGTFPLELIPRSLQHFNAWLPMTYSVFGLKAVISSGDFSFMWENIGKLLLFVVAMMMGTLVYLTIQHRRQFATAVEQASEA
>NZ_CP016552.1|WP_033011731.1|366124_366694_-|TetR/AcrR-family-transcriptional-regulator
MSDKKQQIIDAATQSFSLFGYKATTMDQVAKMANVGKGTIYTFFKSKEELLDHIVSSVISEIKHEADAAMDDRLPFSENVQRALQRIFTFRQEHELTIKLLQEMRDIGTAAVRDVMKRLDREMIAYIREKIEEAMAKGEIRPCDPELTAFFMFKMYIALSIEWEKDHEPLSQQTIAELFDLYLLKGLSP

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Crispr_ID: NZ_CP016552_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_3

355243-355341

TypeII

Consensus_repeat	Method
GTTTTTATCGCACCTATGAGGGATTGAAACT	CRISPRCasFinder

1 spacers

cas9,cas1,cas2,cas6

The CRISPR arrays of NZ_CP016552_3

>merge|NZ_CP016552|3|355243-355341|CRISPRCasFinder
GTTTTTATCGCACCTATGAGGGATTGAAACTCAGGAGCCTCATTTTCATATCGGGGAACTGGATCAAGTTTTTATCGTACCTATGAGGGATTGAAACTT

>NZ_CP016552|3|3|355243-355341|CRISPRCasFinder
GTTTTTATCGCACCTATGAGGGATTGAAACT	CAGGAGCCTCATTTTCATATCGGGGAACTGGATCAA
GTTTTTATCGTACCTATGAGGGATTGAAACTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	unknown	unknown	gnl\|CDD\|239071
NZ_CP016552.1\|WP_095858805.1\|361876_362530_-\|PspA/IM30-family-protein	unknown	unknown	gnl\|CDD\|224755
NZ_CP016552.1\|WP_011229827.1\|358977_359202_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858801.1\|355451_355661_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376019
NZ_CP016552.1\|WP_095858795.1\|336654_340776_+\|TIGR02680-family-protein	unknown	unknown	gnl\|CDD\|274256
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	unknown	unknown	gnl\|CDD\|274255
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	unknown	unknown	gnl\|CDD\|237372
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|225943
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP016552.1\|WP_095858806.1\|362489_363014_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_033024617.1\|363194_363542_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP016552.1\|WP_095858807.1\|363739_366049_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	gnl\|CDD\|239071	cd02253, DmpA, L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active heterodimeric form. The cleavage results in two polypeptide chains, with one chain containing an N-terminal nucleophile. This group represents one of the rare aminopeptidases that are not metalloenzymes. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	4.48423e-175
NZ_CP016552.1\|WP_095858805.1\|361876_362530_-\|PspA/IM30-family-protein	gnl\|CDD\|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	7.13874e-22
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	gnl\|CDD\|376019	pfam18593, CdiI_2, CdiI immunity protein. Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Structure analysis of CdiI immunity protein from Yersinia kristensenii shows that it is composed of eight alpha-helices packed together to form a nearly spherical structure with weak structural homology to a putative TetR family transcriptional repressor. The CdiI protein fits into the curved cavity of the CdiA-CTYkris toxin domain where it most likely neutralizes toxin activity by blocking access to RNA substrates. This domain is mostly found in gammaproteobacteria.	0.000887762
NZ_CP016552.1\|WP_095858795.1\|336654_340776_+\|TIGR02680-family-protein	gnl\|CDD\|274256	TIGR02680, conserved_hypothetical_protein, TIGR02680 family protein. Members of this protein family belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). Proteins in this family average over 1400 amino acids in length. [Hypothetical proteins, Conserved].	0
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.31022e-42
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.29636e-10
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19707e-110
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP016552.1\|WP_095858796.1\|340772_341993_+\|TIGR02679-family-protein	gnl\|CDD\|274255	TIGR02679, conserved_hypothetical_protein, TIGR02679 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	2.0043e-132
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.05989e-06
NZ_CP016552.1\|WP_095858797.1\|342060_342438_+\|transposase	gnl\|CDD\|237372	PRK13386, fliH, flagellar assembly protein H; Provisional.	1.14699e-06
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	gnl\|CDD\|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	1.80502e-24
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.47396e-99
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.50141e-44
NZ_CP016552.1\|WP_095858807.1\|363739_366049_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	7.50419e-158
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.53622e-36

>NZ_CP016552.1|WP_095860176.1|354681_355047_+|transposase
MLVRLELDEAKQRLLFGFFETYLRLSEEEEAKPRHEVSQMETKEAKRVMELIVSYEQRGLEKGIQQGIEQGIKQGMKQGRQEGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858800.1|351023_354287_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MRYKIGLDIGITSVGWAVINLDIPRIEDLGVRIFDRAENPQTGESLALPRRLARSARRRLRRRKHRLERIRRLVIREGILTKEELDKLFEEKHEIDVWQLRVEALDRKLNNDELARVLLHLAKRRGFKSNRKSERSNKENSTMLKHIEENRAILSGYRTVGEMIVKDPKFALHKRNKGENYTNTIARDDLEHEIRLIFSKQREFGNMSCTEKFENEYITIWASQRPVASKDDIEKKVGFCTFEPKEKRAPKATYTFQSFIAWEHINKLRLISPSGTRGLTDEERRLLYEQAFQKNKITYHDIWTLLRLPDDTYFKGIVYDRGESRKQNENIRFLELDAYHQIRKAVDKVYGKGKSSSFLPIDFDTFGYALTLFKDDADIRSYLQNEYEQNGKRMPNLANKVYDNELIEELLNLSFTKFGHLSLKALRSILPYMEQGEVYSSACERAGYTFTGPKKKQKTMLLPNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARDLSQTFDERRKTKKEQDENRKKNETAIRQLMEYGLTLNPTGHDIVKFKLWSEQNGRCAYSLQPIEIERLLEPGYVEVDHVIPYSRSLDDSYTNKVLVLTRENREKGNRIPAEYLGVGTERWQQFETFVLTNKQFSKKKRDRLLRLHYDENEETEFKNRNLNDTRYISRFFANFIREHLKFAESDDKQKVYTVNGRVTSHLRSRWDFNKNREESDLHHAVDAAIVACTTPSDIAKVTAFYQRREQNKELAKKTEPHFPQPWPHFADELRARLSKHPKESIKALNLGNYDDQKLESLQPVFVSRMPKRSVTGAAHQETLRRYIGIDERSGKIQTVVKTKLSEIKLDASGHFPMYGKESDPRTYEAIRQRLLEHNNDPKKAFQEPLYKPKKNGEPGPIIRTVKIIDTKNQVIPLNDGKTVAYNSNIVRVDVFEKDGKYYCVPVYTMDIMKGILPNKAIEPNKPYSEWKEMTEDYTFRFSLYPNDLIRIELPREKTVKTTTGEEINVKDVFVYYKTIDSATGGLELISHDNRFSLRGVGSRTLKRFEKYQVDVLGNIYKVRGEKRVGLASSAHSKTGETIRPLQSTRD
>NZ_CP016552.1|WP_050368140.1|350194_351094_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRHLLIRKPGKLSVRYNQLVIEQEEKVSIPLEDICSIIIEEQAVSVTAAALSKMAEHNITLFTCDQKRLPNGVLQPFQKHSRQVGVLHMQYAYSKPFKKRIWQRIVIQKLINQGKCLEFLNKEGADDLYRISKTVDSGDSNNREAYGAKKYFQYLFGSEFTRRSDSVVNASLNYGYAIMRGLVARSLVGYGFLPCLGIYHDNELNKFNLADDFMEVLRPLVDLYVAQHIQPDDEFSPSIRADLYNLVNMDILVNGEKLTVVNAVEEMTKSFVTASRSQDPSLLKLPELLPLQLHVYE
>NZ_CP016552.1|WP_033016933.1|349881_350190_-|CRISPR-associated-endonuclease-Cas2
MRLLVFFDLPVVTNREKREYRRFRTFLLNEGYDMLQFSVYSRVCHGHEATDKHLARLKRNLPPRGSIRAMVVTEKQYAKMQLLLGEPTAQEKKVTSTQLTLF
>NZ_CP016552.1|WP_095858799.1|345335_346619_-|peptidoglycan-binding-protein
MYVVDASGRHYYPSNYTNYLWNGQTLRKGDRGAYVKTLQSWLHKAGFNPGAIDGIYGANTEKAVKEFQKKVGITADGIAGKQTYNALQSYLRTQTSTSKSTSSTSNNSNDWTGQTLRKGSQGESVKDLQIMLNYAGYNVKVDGIYGSETEKAVRSFQKSVGISVDGIAGAQTYKSLNSYISSKANKGVTIDISKEAQRLQKEAEEKKKQELAKALIDVATDFVPVVGQFKDAYNLVNTLFNPNATAKEVGLALFAFIPAVGDLKNIGKAIDAIKSTVKKGTDKIDDAAIDFISKKIREINASDLLLYSEKAGGHTISEHISLSDTQMVKRAAQQKIDVTSYTNQNTAIKVIKSALSQNASKIAEWLLDPNSRDRLNLNQEMGYAIGKGYKSGGTALKTNLDTAFIQLKKDSKSKYGFIIVTSYPKYK
>NZ_CP016552.1|WP_095858798.1|345023_345323_-|hypothetical-protein
MDIRKEFENLQYFFDSYYNQTFYDAKLEDKFLEFLNDEPKWVSKALKEEIKKLEQIYNNKDINTWAKIEELVHENSMRYFPYEDGKKFIEIANKFLENV
>NZ_CP016552.1|WP_015374552.1|342855_343901_-|IS630-like-element-ISBs2-family-transposase
MMPNHKDEIEKLSTAMKEAKSKRAYERYQAIYLHLQGYTKGEIATIIGRSKKTIYNYIHAYAQRGLDGLEMKYSPGAPRRLTPEQEKELALIIEHQLPVDVGFEAKYNWTLAIIAELIQQKWGPTYTLRGTSDILHRLGLSYTKPTYTLANADEEKQKEFVEITFPEVKKLVDGNIAHVLFQDESMIRDYQAIQKTWFVKGKQRIIPTFGKHQGLKLIGTLNYETGEVFCIEEERYDAETFLRFLQLVLERYPTGKIVMILDNARIHHAKLIQPFLKEHEDRLELVFLPPYSPQLNLIEGLWKWLKSDVIYNVFYSSVQEIRKNVQAFIQRINQKPEQTIDRLCVQL
>NZ_CP016552.1|WP_095858797.1|342060_342438_+|transposase
MLARLELDEAKQRLLFGFFETYLRRSEEEEAKRRHEVSQMETKEAKQVMELIVSYEQRGMEKGIEKGIEQGVKQGIKQGIKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858796.1|340772_341993_+|TIGR02679-family-protein
MSTAKEAAAFFRSEPGFRRLFIEMKHKYESLGRVGGAVSLEAFTDEEREAVAAFFGKDVSRVSLIAFEKQLGQTRFAGVGLVELLEQYFGAPLVSNKERRQAEEEERDRFFARLTEEHHWVESVRPQRFVQTAYETDRRSLEEAIRLVSAALGRLPLPSYMRLPLFAQQVAGDPHAFDLSTLPGRLLLSALQATVPGDWDMASVESVNELLQSVGLLREDILNFVTCANILAETEGGPHPVFSAASETNTALNMPLRDVLSLVRARPAHGGTVYIVENAGVFSTLLDTRAPLVSTNGQMNLATMKLLDLLASSGAKLYYSGDFDPEGLAMAERLQERYGQAVTLWRFSVEDYRAANPVVDLTPERLAKLASVTSTPLQPLKEEMAETKKAGYQEAIIGRLTGDING
>NZ_CP016552.1|WP_095858795.1|336654_340776_+|TIGR02680-family-protein
MANPWVLHRAGLINFWYYDEQYFHFADGKLLLRGSNGAGKSVTMQSLIPVLLDGKKTPDRLDPFGSRARRMEDYLLGEKDVVNRDERTGYLFLEYKRKASDQYVTTGIGLRAKRQKSLDFWGFVIFDNRRIGHHLTLYKKEKTGEKIPLTKRELAALLGAGGTVVDTQKEYMELVNKHVFRFESLESFQELIELLIQLRSPKLSKDFKPTVIYEILESSLPPLTDDELRHLSDTIENMDQAKQQLEQLERDERALKRLCDQYRLYNEYMIAEKAAEYVKAVKQAEQLAAEQQRLHDEEERARTMLDELEESITRLGREEDVLRAREIDLAGHEVFQQAEKYEQLKAEQQRLEERRKRHEQTIAEKERQERQHRRRLDEAEARLDDLERKLEDELEQLRMDADEGSFSLHETNEGDFHRHRQKEQEFLFAAWKQEADRHIERLEGLARLWRRHDEVKQRYEEASSEAGERQREMDEWRHQQRKWEELLEQEKERFEQAVLAWIGQGDVDISEADIQSFLQQMDALYEQYSLDDLKRPFVQAYYDAVGKKKDEKWRLEHDIRLLEEKRAEREAELRRWREQRDPEPERDEQTTAARLALEEKGIPFVPLYAAVEFVDDVPDDVRERIESALSHAGLLDALITAREIDVACDRVLIPKPVHMAHTLADYLRPDANAPVSMERIDEVLRSIVITDADQEGGMTIDETGRYSLGLVRGHAPRRSKAMFIGRAARERWRLENIAALEAEIAAVGQEIDRLRGAHEDVEAAIQALADWLASFPSDRDVRTAFDEAQEARRQAESKEREWKRQEEKAALLAREWKQIKQQLRDESAELDLAFTLDGCEQAMLAMKSYVRHLHELEVLYRETRHTEAVIAQQREQLAVLEAEIDEAKGERNRLRDETERLALRIAEMERTLAQMGADDIRAEIARIQERLASLRREIPRLVNERARTEQQLMRLVEEREKGAQREEFARELAAMWEKSFAREAALGLVDLDRSRSLLEQAKEAKQRYEAVLKETRSSLLARLNTVFFQESSNLTEYRASFEPLEEQTKPEWTAAAPDDEMAMKAADWREKQERHVIYLDYKGERATPFAVLAEVERDIVLQHEYMKEQDRELYEDVILKSVGRILRSRIQRAERWVNDMNKLMGGLDTSSGLVLSIQWKPKTAETEAELDTKELVRLLRLDPRLLREEDLQRVTNHFRSKIARARELLEERGQGSTLHQIIKEVLDYRKWFSFTLYYEKTNEPKRELTNHRFYQFSGGEKAMAMYIPLFAAAYSRYQEAGDDAPYIISLDEAFAGVDENNIRNLFGLVEQLGFNYIMNSQALWGDYDTVPALSICELVRPRNASFVTVIHYRWNGRVKQLMVNDKEWETIET
>NZ_CP016552.1|WP_095858801.1|355451_355661_+|hypothetical-protein
MITIYDLIGYIQNMDNMDKLDEIISRWYFQTPVWTSQVKEEVKKAVVEILQLGEPKVYQFFVDMYGLKM
>NZ_CP016552.1|WP_095858802.1|355827_356712_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIRTFFEEFLLLFFPDMHEHIDFHHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVETQGYVQPTFAERMFLYFSRLYETYRTRIVPIAVFHYDSLREEPSVFSMEFPFGEVLQFRFFPVALRKKQWREYIRHDNPVAAALLSQMGYTEREKVELKKEFLRMQVRLELDEARQRLLLGFFETYVKLTEEEEQQLQSEVKAMETKEREKVLELIISYEQKGKKEGLEEGVKRGLEQGMKQGMKRLIETMAQKGMTAAEIARLVDLSEEEVRSLLSE
>NZ_CP016552.1|WP_042382835.1|357744_358491_+|CRISPR-associated-endoribonuclease-Cas6
MRLTITMSGRQGPVSLPLHYQHLLQGMLYRSLENEQLAAFLHDKGFRHGKRSFKLFTFSRLFGTHQVDRGKKAIRFLDDFQWHIDTVLPELTQQLGQRFLLQREIELYGQLIEVKSVKMENIDIRENEIDIVMLSPLTVYSTYETFDGRKKTQFFDPDDEVFPHLIELNFRHKYEAYYGVPPTERLLIEPIHVHHRHRVVTMFKNMYITGWLGYYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLKSE
>NZ_CP016552.1|WP_011229827.1|358977_359202_-|hypothetical-protein
MQQRQRKAVNNHAWWINGAIQKKQMPKRSPCAKQKSGFLQSKRRKNEQPKQNEAVDRGSAAIRFLQTEDVHTMA
>NZ_CP016552.1|WP_095858803.1|359338_360385_+|P1-family-peptidase
MRRKLRDLGFSIGTLPVGRRNQITDVPGVRVGHVTIREERDERTVVRTGVTAVLPHGGNWFLEKVPAACFVLNGFGKTAGLVQVEELGTIESPIMLTNTFSVGAVWQGTLEYMLEATPEIGDVTGSVNIVVGECNDSYLNTARALSVTKEHAKEAIAAARVEMEEGAIGAGTGMMCFGWKGGVGSSSRVVSRGYTVGALVVSNFGRREELRFVPYMPPSFDERDVPPGSIMMIVATDAPLDARQLKRLAKRAAVGLGRTGSCVHHGSGDIVIAFSNAYTIPHFSDSALQSVPPLIRDDAPLMNELFQAAIEATEEAIWNSLTMAETTTGRNGRIGEAIPYALLRRMGE
>NZ_CP016552.1|WP_095858804.1|360445_361678_-|MFS-transporter
MNWKRSVRVLWLCNFMVSAGMTMVIPFLSLLLWEMGVTEHHSLSVWTGLVFSATFLSAAIMAPIWGMFADKYGQRANLIRAGIGMGLITGCMAFAASPMALLALRFLVGFFSGFITVSFSYLARVVPKDHSGEALGTLQTGSIAGNIIGPLIGGALSDWFGFRPVFLMTGFCILATLLPVVFWLDKDPVAPQTQERHASFKEVFAHRPLVILFVATFLVQIAVLGVNSMMTIFVQSLVGDSRNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQEKTLPILLVLSGLFALPQVWTDHLYELYVWRFLQGLVVGGVWPALQALINAQCPRRIQGRVFGVTASSRFLGNLAGPTAAGAIAGFASISAIFALSGLLLIATGALVGSTTRDRAWREDMKEKIAAWAHRLHIRH
>NZ_CP016552.1|WP_095858805.1|361876_362530_-|PspA/IM30-family-protein
MGIFRRMKTIVLAEVNEQIDRWEDPVAMTKQYLRELEEQLERGRQALAQQWVAERRYETLIAQAEATIEKRSRQAKLALERNEEAVAKLALRDKLLYEKKLEAYKQQYDAIKAKTAEVANRLNQLRERYDELAAKQLELATRVNAAQALKQIDSALASFSADEALRGFARMEERVIALEAEAAAARFGTNAVLSPVPFDEEVERELAKWKEAQANNA
>NZ_CP016552.1|WP_095858806.1|362489_363014_-|hypothetical-protein
MKKARAVFLLALVALAGVSLFHVLAPHEVMAHGRPGAPFDGMPGGFGHPHREFIMEQRGGWMMPMLFLKWLIPLLLAAAGAVWLAAARSKRWIGWVLVALGIAALLPKWVLLLLALAAVYALGRRQARKPSAVEALMPAAPSVSADWLDEWEKTIQKEAQTNGHFSPNEDDRSR
>NZ_CP016552.1|WP_033024617.1|363194_363542_+|hypothetical-protein
MVRSYGVDVGGALLVLWFSFLFPTFYVGYYAYGSFLGFAIGSLIVGLARIRWHPQARFGGTLIGSFLIIAVSVLIIRLFPIEIRDVGDLVMQYINAVVNALIYLAFSTPSTCCIA
>NZ_CP016552.1|WP_095858807.1|363739_366049_-|YhgE/Pip-domain-containing-protein
MHAFQLWLKEWKAILTNRKVLIPVIAVLFIPLLYSGMFLWAFWDPYNHLDELPVAVVNQDKGAMLDGKEIHLGKDLVEKLKENKQFDWHFVTEHEGEKGLKEQKYYMLIQIPDDFSRNATTLQDDHPKKLELIYKPNEGFNFLSAQIGQTAVEKIKNEVANAITETYAESMFDTIQTVADGLTKASDGAARLHDGLSQAQDGTNRLYDGMKKAQDGSETLYHHLATLAEKSVSFTDGLHQAASGSLQVQTGSEALYNGMKQMTAGQEKLLSGAKQAQQGAANLASGTRRVYEGMQTLDARMPRLLQGSEQLSGGAEKLASSLAQWQQGAARVQTGATQVTGGLEQLAAQLDALIAQTPDPTQKAVYERLKENVEKLSFGSKQVENGLAQLNSGAQSLHSGASSLHEGAQKLHEGHIALDRGVDELLAGQQQLVNGADALANGQEQLVSGMKTMYDKMQEAAQGASQLAHGSGTLSSGLQTLAQGADQLQDGTRRLANGSQQVADGTKELTNGTKHLQDGVNQLTDGSKELANKLKEGAEQASDVKANEAVYDMFAQPVNLHKEEINKVPNYGTGFTPYFLSLGLFVGALLLSIVFPLREPAEIPRSPLHWFLAKFGVLIGIGILQALLADVVLLVGLDLHVKSVPLFIVFSIVTSITFLSVIQFLVTVFGDPGRFIAIVVLILQLTTSAGTFPLELIPRSLQHFNAWLPMTYSVFGLKAVISSGDFSFMWENIGKLLLFVVAMMMGTLVYLTIQHRRQFATAVEQASEA

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Crispr_ID: NZ_CP016552_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_5

358674-358902

TypeII

Consensus_repeat	Method
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRT

3 spacers

cas6,cas9,cas1,cas2

The CRISPR arrays of NZ_CP016552_5

>merge|NZ_CP016552|5|358674-358902|PILER-CR,CRISPRCasFinder,CRT
GTTTTTATCGTACCTATGAGGGATTGAAACAGATGTCTGGGCAGGGTTGTCGTGAGTTTGAACAGTGTTTTTATCGTACCTATGAGGGATTGAAACGAAAATTTAATGTTAGTGATCCGTTTACGATCGCCAGTTTTTATCGTACCTATGAGGGATTGAAAACCGTTTGACCTTTGTAATATTTTGGCTGTTATCAATGGTTTTTATCGTACCTACGAGGGATTGAAAC

>NZ_CP016552|5|4|358674-358902|PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGATGTCTGGGCAGGGTTGTCGTGAGTTTGAACAGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GAAAATTTAATGTTAGTGATCCGTTTACGATCGCCA
GTTTTTATCGTACCTATGAGGGATTGAAAA	CCGTTTGACCTTTGTAATATTTTGGCTGTTATCAATG
GTTTTTATCGTACCTACGAGGGATTGAAAC

>NZ_CP016552|5|5|358674-358902|CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGATGTCTGGGCAGGGTTGTCGTGAGTTTGAACAGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GAAAATTTAATGTTAGTGATCCGTTTACGATCGCCA
GTTTTTATCGTACCTATGAGGGATTGAAAA	CCGTTTGACCTTTGTAATATTTTGGCTGTTATCAATG
GTTTTTATCGTACCTACGAGGGATTGAAAC

>NZ_CP016552|5|2|358674-358902|CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGATGTCTGGGCAGGGTTGTCGTGAGTTTGAACAGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GAAAATTTAATGTTAGTGATCCGTTTACGATCGCCA
GTTTTTATCGTACCTATGAGGGATTGAAAA	CCGTTTGACCTTTGTAATATTTTGGCTGTTATCAATG
GTTTTTATCGTACCTACGAGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_095858805.1\|361876_362530_-\|PspA/IM30-family-protein	unknown	unknown	gnl\|CDD\|224755
NZ_CP016552.1\|WP_095858807.1\|363739_366049_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NZ_CP016552.1\|WP_095858808.1\|366869_368243_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|380161
NZ_CP016552.1\|WP_095858801.1\|355451_355661_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376019
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_044743566.1\|368232_368895_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP016552.1\|WP_033011731.1\|366124_366694_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	unknown	unknown	gnl\|CDD\|239071
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|225943
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP016552.1\|WP_095858806.1\|362489_363014_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_033024617.1\|363194_363542_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP016552.1\|WP_011229827.1\|358977_359202_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_095858805.1\|361876_362530_-\|PspA/IM30-family-protein	gnl\|CDD\|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	7.13874e-22
NZ_CP016552.1\|WP_095858807.1\|363739_366049_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	7.50419e-158
NZ_CP016552.1\|WP_095858798.1\|345023_345323_-\|hypothetical-protein	gnl\|CDD\|376019	pfam18593, CdiI_2, CdiI immunity protein. Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Structure analysis of CdiI immunity protein from Yersinia kristensenii shows that it is composed of eight alpha-helices packed together to form a nearly spherical structure with weak structural homology to a putative TetR family transcriptional repressor. The CdiI protein fits into the curved cavity of the CdiA-CTYkris toxin domain where it most likely neutralizes toxin activity by blocking access to RNA substrates. This domain is mostly found in gammaproteobacteria.	0.000887762
NZ_CP016552.1\|WP_095858804.1\|360445_361678_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19707e-110
NZ_CP016552.1\|WP_033016933.1\|349881_350190_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.31022e-42
NZ_CP016552.1\|WP_095858802.1\|355827_356712_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.29636e-10
NZ_CP016552.1\|WP_044743566.1\|368232_368895_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.23351e-78
NZ_CP016552.1\|WP_033011731.1\|366124_366694_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.99354e-16
NZ_CP016552.1\|WP_095858800.1\|351023_354287_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP016552.1\|WP_095858803.1\|359338_360385_+\|P1-family-peptidase	gnl\|CDD\|239071	cd02253, DmpA, L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active heterodimeric form. The cleavage results in two polypeptide chains, with one chain containing an N-terminal nucleophile. This group represents one of the rare aminopeptidases that are not metalloenzymes. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	4.48423e-175
NZ_CP016552.1\|WP_095860176.1\|354681_355047_+\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.05989e-06
NZ_CP016552.1\|WP_095858799.1\|345335_346619_-\|peptidoglycan-binding-protein	gnl\|CDD\|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	1.80502e-24
NZ_CP016552.1\|WP_050368140.1\|350194_351094_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.47396e-99
NZ_CP016552.1\|WP_095858808.1\|366869_368243_-\|GHKL-domain-containing-protein	gnl\|CDD\|380161	NF033092, HK_WalK, cell wall metabolism sensor histidine kinase WalK. This model describes WalK as found in Staphylococcus aureus (sp\|Q2G2U4.1\|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.	4.62201e-72
NZ_CP016552.1\|WP_015374552.1\|342855_343901_-\|IS630-like-element-ISBs2-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.50141e-44
NZ_CP016552.1\|WP_042382835.1\|357744_358491_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.53622e-36

>NZ_CP016552.1|WP_042382835.1|357744_358491_+|CRISPR-associated-endoribonuclease-Cas6
MRLTITMSGRQGPVSLPLHYQHLLQGMLYRSLENEQLAAFLHDKGFRHGKRSFKLFTFSRLFGTHQVDRGKKAIRFLDDFQWHIDTVLPELTQQLGQRFLLQREIELYGQLIEVKSVKMENIDIRENEIDIVMLSPLTVYSTYETFDGRKKTQFFDPDDEVFPHLIELNFRHKYEAYYGVPPTERLLIEPIHVHHRHRVVTMFKNMYITGWLGYYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLKSE
>NZ_CP016552.1|WP_095858802.1|355827_356712_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIRTFFEEFLLLFFPDMHEHIDFHHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVETQGYVQPTFAERMFLYFSRLYETYRTRIVPIAVFHYDSLREEPSVFSMEFPFGEVLQFRFFPVALRKKQWREYIRHDNPVAAALLSQMGYTEREKVELKKEFLRMQVRLELDEARQRLLLGFFETYVKLTEEEEQQLQSEVKAMETKEREKVLELIISYEQKGKKEGLEEGVKRGLEQGMKQGMKRLIETMAQKGMTAAEIARLVDLSEEEVRSLLSE
>NZ_CP016552.1|WP_095858801.1|355451_355661_+|hypothetical-protein
MITIYDLIGYIQNMDNMDKLDEIISRWYFQTPVWTSQVKEEVKKAVVEILQLGEPKVYQFFVDMYGLKM
>NZ_CP016552.1|WP_095860176.1|354681_355047_+|transposase
MLVRLELDEAKQRLLFGFFETYLRLSEEEEAKPRHEVSQMETKEAKRVMELIVSYEQRGLEKGIQQGIEQGIKQGMKQGRQEGIEEGKLDVVKRMLAKGYDVDTIHELTGLPMEKIERMKG
>NZ_CP016552.1|WP_095858800.1|351023_354287_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MRYKIGLDIGITSVGWAVINLDIPRIEDLGVRIFDRAENPQTGESLALPRRLARSARRRLRRRKHRLERIRRLVIREGILTKEELDKLFEEKHEIDVWQLRVEALDRKLNNDELARVLLHLAKRRGFKSNRKSERSNKENSTMLKHIEENRAILSGYRTVGEMIVKDPKFALHKRNKGENYTNTIARDDLEHEIRLIFSKQREFGNMSCTEKFENEYITIWASQRPVASKDDIEKKVGFCTFEPKEKRAPKATYTFQSFIAWEHINKLRLISPSGTRGLTDEERRLLYEQAFQKNKITYHDIWTLLRLPDDTYFKGIVYDRGESRKQNENIRFLELDAYHQIRKAVDKVYGKGKSSSFLPIDFDTFGYALTLFKDDADIRSYLQNEYEQNGKRMPNLANKVYDNELIEELLNLSFTKFGHLSLKALRSILPYMEQGEVYSSACERAGYTFTGPKKKQKTMLLPNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARDLSQTFDERRKTKKEQDENRKKNETAIRQLMEYGLTLNPTGHDIVKFKLWSEQNGRCAYSLQPIEIERLLEPGYVEVDHVIPYSRSLDDSYTNKVLVLTRENREKGNRIPAEYLGVGTERWQQFETFVLTNKQFSKKKRDRLLRLHYDENEETEFKNRNLNDTRYISRFFANFIREHLKFAESDDKQKVYTVNGRVTSHLRSRWDFNKNREESDLHHAVDAAIVACTTPSDIAKVTAFYQRREQNKELAKKTEPHFPQPWPHFADELRARLSKHPKESIKALNLGNYDDQKLESLQPVFVSRMPKRSVTGAAHQETLRRYIGIDERSGKIQTVVKTKLSEIKLDASGHFPMYGKESDPRTYEAIRQRLLEHNNDPKKAFQEPLYKPKKNGEPGPIIRTVKIIDTKNQVIPLNDGKTVAYNSNIVRVDVFEKDGKYYCVPVYTMDIMKGILPNKAIEPNKPYSEWKEMTEDYTFRFSLYPNDLIRIELPREKTVKTTTGEEINVKDVFVYYKTIDSATGGLELISHDNRFSLRGVGSRTLKRFEKYQVDVLGNIYKVRGEKRVGLASSAHSKTGETIRPLQSTRD
>NZ_CP016552.1|WP_050368140.1|350194_351094_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRHLLIRKPGKLSVRYNQLVIEQEEKVSIPLEDICSIIIEEQAVSVTAAALSKMAEHNITLFTCDQKRLPNGVLQPFQKHSRQVGVLHMQYAYSKPFKKRIWQRIVIQKLINQGKCLEFLNKEGADDLYRISKTVDSGDSNNREAYGAKKYFQYLFGSEFTRRSDSVVNASLNYGYAIMRGLVARSLVGYGFLPCLGIYHDNELNKFNLADDFMEVLRPLVDLYVAQHIQPDDEFSPSIRADLYNLVNMDILVNGEKLTVVNAVEEMTKSFVTASRSQDPSLLKLPELLPLQLHVYE
>NZ_CP016552.1|WP_033016933.1|349881_350190_-|CRISPR-associated-endonuclease-Cas2
MRLLVFFDLPVVTNREKREYRRFRTFLLNEGYDMLQFSVYSRVCHGHEATDKHLARLKRNLPPRGSIRAMVVTEKQYAKMQLLLGEPTAQEKKVTSTQLTLF
>NZ_CP016552.1|WP_095858799.1|345335_346619_-|peptidoglycan-binding-protein
MYVVDASGRHYYPSNYTNYLWNGQTLRKGDRGAYVKTLQSWLHKAGFNPGAIDGIYGANTEKAVKEFQKKVGITADGIAGKQTYNALQSYLRTQTSTSKSTSSTSNNSNDWTGQTLRKGSQGESVKDLQIMLNYAGYNVKVDGIYGSETEKAVRSFQKSVGISVDGIAGAQTYKSLNSYISSKANKGVTIDISKEAQRLQKEAEEKKKQELAKALIDVATDFVPVVGQFKDAYNLVNTLFNPNATAKEVGLALFAFIPAVGDLKNIGKAIDAIKSTVKKGTDKIDDAAIDFISKKIREINASDLLLYSEKAGGHTISEHISLSDTQMVKRAAQQKIDVTSYTNQNTAIKVIKSALSQNASKIAEWLLDPNSRDRLNLNQEMGYAIGKGYKSGGTALKTNLDTAFIQLKKDSKSKYGFIIVTSYPKYK
>NZ_CP016552.1|WP_095858798.1|345023_345323_-|hypothetical-protein
MDIRKEFENLQYFFDSYYNQTFYDAKLEDKFLEFLNDEPKWVSKALKEEIKKLEQIYNNKDINTWAKIEELVHENSMRYFPYEDGKKFIEIANKFLENV
>NZ_CP016552.1|WP_015374552.1|342855_343901_-|IS630-like-element-ISBs2-family-transposase
MMPNHKDEIEKLSTAMKEAKSKRAYERYQAIYLHLQGYTKGEIATIIGRSKKTIYNYIHAYAQRGLDGLEMKYSPGAPRRLTPEQEKELALIIEHQLPVDVGFEAKYNWTLAIIAELIQQKWGPTYTLRGTSDILHRLGLSYTKPTYTLANADEEKQKEFVEITFPEVKKLVDGNIAHVLFQDESMIRDYQAIQKTWFVKGKQRIIPTFGKHQGLKLIGTLNYETGEVFCIEEERYDAETFLRFLQLVLERYPTGKIVMILDNARIHHAKLIQPFLKEHEDRLELVFLPPYSPQLNLIEGLWKWLKSDVIYNVFYSSVQEIRKNVQAFIQRINQKPEQTIDRLCVQL
>NZ_CP016552.1|WP_011229827.1|358977_359202_-|hypothetical-protein
MQQRQRKAVNNHAWWINGAIQKKQMPKRSPCAKQKSGFLQSKRRKNEQPKQNEAVDRGSAAIRFLQTEDVHTMA
>NZ_CP016552.1|WP_095858803.1|359338_360385_+|P1-family-peptidase
MRRKLRDLGFSIGTLPVGRRNQITDVPGVRVGHVTIREERDERTVVRTGVTAVLPHGGNWFLEKVPAACFVLNGFGKTAGLVQVEELGTIESPIMLTNTFSVGAVWQGTLEYMLEATPEIGDVTGSVNIVVGECNDSYLNTARALSVTKEHAKEAIAAARVEMEEGAIGAGTGMMCFGWKGGVGSSSRVVSRGYTVGALVVSNFGRREELRFVPYMPPSFDERDVPPGSIMMIVATDAPLDARQLKRLAKRAAVGLGRTGSCVHHGSGDIVIAFSNAYTIPHFSDSALQSVPPLIRDDAPLMNELFQAAIEATEEAIWNSLTMAETTTGRNGRIGEAIPYALLRRMGE
>NZ_CP016552.1|WP_095858804.1|360445_361678_-|MFS-transporter
MNWKRSVRVLWLCNFMVSAGMTMVIPFLSLLLWEMGVTEHHSLSVWTGLVFSATFLSAAIMAPIWGMFADKYGQRANLIRAGIGMGLITGCMAFAASPMALLALRFLVGFFSGFITVSFSYLARVVPKDHSGEALGTLQTGSIAGNIIGPLIGGALSDWFGFRPVFLMTGFCILATLLPVVFWLDKDPVAPQTQERHASFKEVFAHRPLVILFVATFLVQIAVLGVNSMMTIFVQSLVGDSRNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQEKTLPILLVLSGLFALPQVWTDHLYELYVWRFLQGLVVGGVWPALQALINAQCPRRIQGRVFGVTASSRFLGNLAGPTAAGAIAGFASISAIFALSGLLLIATGALVGSTTRDRAWREDMKEKIAAWAHRLHIRH
>NZ_CP016552.1|WP_095858805.1|361876_362530_-|PspA/IM30-family-protein
MGIFRRMKTIVLAEVNEQIDRWEDPVAMTKQYLRELEEQLERGRQALAQQWVAERRYETLIAQAEATIEKRSRQAKLALERNEEAVAKLALRDKLLYEKKLEAYKQQYDAIKAKTAEVANRLNQLRERYDELAAKQLELATRVNAAQALKQIDSALASFSADEALRGFARMEERVIALEAEAAAARFGTNAVLSPVPFDEEVERELAKWKEAQANNA
>NZ_CP016552.1|WP_095858806.1|362489_363014_-|hypothetical-protein
MKKARAVFLLALVALAGVSLFHVLAPHEVMAHGRPGAPFDGMPGGFGHPHREFIMEQRGGWMMPMLFLKWLIPLLLAAAGAVWLAAARSKRWIGWVLVALGIAALLPKWVLLLLALAAVYALGRRQARKPSAVEALMPAAPSVSADWLDEWEKTIQKEAQTNGHFSPNEDDRSR
>NZ_CP016552.1|WP_033024617.1|363194_363542_+|hypothetical-protein
MVRSYGVDVGGALLVLWFSFLFPTFYVGYYAYGSFLGFAIGSLIVGLARIRWHPQARFGGTLIGSFLIIAVSVLIIRLFPIEIRDVGDLVMQYINAVVNALIYLAFSTPSTCCIA
>NZ_CP016552.1|WP_095858807.1|363739_366049_-|YhgE/Pip-domain-containing-protein
MHAFQLWLKEWKAILTNRKVLIPVIAVLFIPLLYSGMFLWAFWDPYNHLDELPVAVVNQDKGAMLDGKEIHLGKDLVEKLKENKQFDWHFVTEHEGEKGLKEQKYYMLIQIPDDFSRNATTLQDDHPKKLELIYKPNEGFNFLSAQIGQTAVEKIKNEVANAITETYAESMFDTIQTVADGLTKASDGAARLHDGLSQAQDGTNRLYDGMKKAQDGSETLYHHLATLAEKSVSFTDGLHQAASGSLQVQTGSEALYNGMKQMTAGQEKLLSGAKQAQQGAANLASGTRRVYEGMQTLDARMPRLLQGSEQLSGGAEKLASSLAQWQQGAARVQTGATQVTGGLEQLAAQLDALIAQTPDPTQKAVYERLKENVEKLSFGSKQVENGLAQLNSGAQSLHSGASSLHEGAQKLHEGHIALDRGVDELLAGQQQLVNGADALANGQEQLVSGMKTMYDKMQEAAQGASQLAHGSGTLSSGLQTLAQGADQLQDGTRRLANGSQQVADGTKELTNGTKHLQDGVNQLTDGSKELANKLKEGAEQASDVKANEAVYDMFAQPVNLHKEEINKVPNYGTGFTPYFLSLGLFVGALLLSIVFPLREPAEIPRSPLHWFLAKFGVLIGIGILQALLADVVLLVGLDLHVKSVPLFIVFSIVTSITFLSVIQFLVTVFGDPGRFIAIVVLILQLTTSAGTFPLELIPRSLQHFNAWLPMTYSVFGLKAVISSGDFSFMWENIGKLLLFVVAMMMGTLVYLTIQHRRQFATAVEQASEA
>NZ_CP016552.1|WP_033011731.1|366124_366694_-|TetR/AcrR-family-transcriptional-regulator
MSDKKQQIIDAATQSFSLFGYKATTMDQVAKMANVGKGTIYTFFKSKEELLDHIVSSVISEIKHEADAAMDDRLPFSENVQRALQRIFTFRQEHELTIKLLQEMRDIGTAAVRDVMKRLDREMIAYIREKIEEAMAKGEIRPCDPELTAFFMFKMYIALSIEWEKDHEPLSQQTIAELFDLYLLKGLSP
>NZ_CP016552.1|WP_095858808.1|366869_368243_-|GHKL-domain-containing-protein
MKNNWREWRDWLRRLGSADLFRRAHWRLTALYSGIFTLFLALFVMIAAALFYWIATSDQERRISRLAEQEANTIEQVLLKQSNFDLFDDENVILLSEDQLFFYVIGPDGGLLAGDEVHPRLRPYFLNALSHLKANERAPVYMSVSLPEHMPGLAREAARDWRVLAAARPLVIHGDFVGMLYIGMDVTSFFGVFHWLLIVLIGLSVLFLAVGVALSFFMSKRALAPIEEAYERQRQFVADASHELRTPLSVVFSSVEALALEEDVMKNDFARRLLDRLRDELKRITKLMNDLLTLARADAKHAALELSKQTFDFRPHAERTFQLMSELAAKKQITMHFHAPEQALVTADPDKLTQLLYILLDNAIKYTPEGGEVTLSIRTEPKHVFLSVKDTGIGIPPEDIGRIFDRFYRVDKTRSRQQGGHGLGLSIAKWIVDAHGGAIHVHSQIGKGTEFLVRLPR
>NZ_CP016552.1|WP_044743566.1|368232_368895_-|response-regulator-transcription-factor
MKILLAEDDLHLGELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDGVDICRRLRQNGYTGAILMLTAKDAVHDRVTGLEAGADDYLVKPFEIDELVARLKALARRTFVPLQEEKVAFHGFTLNRTSHTLHRSDEEIFLTPREFQLLDLLVQNQGQVVPRETILDRVWGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIEK

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Crispr_ID: NZ_CP016552_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_6

1831685-1831982

TypeV

Consensus_repeat	Method
TGTTTCAATCCCTCATAGGTACGATAAAAAC	CRISPRCasFinder
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRT
GTTTTTATCGTACCTATGAGGGATTGAAACA	PILER-CR

4 spacers

The CRISPR arrays of NZ_CP016552_6

>merge|NZ_CP016552|6|1831685-1831982|CRISPRCasFinder,CRT,PILER-CR
AGTTTCAGTTCCTCATGGGTACGATAAAAACGTTCATCATCGTTGACGGGTTCCATCGGTACACGATTTTGTTTCAATCCCTCATAGGTACGATAAAAACACAAAGGAACATGGATAGGATTTGCCTCCATGCGTTGTTTCAATCCCTCATAGGTACGATAAAAACAAGACCCATTTGCAAATCGCCCTGGCTAAACGGCTCATGTTTCAATCCCTCATAGGTACGATAAAAACCATCACCCATCTCTTCAACTTTTCCGAGAACTCAGTTTCAATCCCTCATAGGTACGATAAAAAC

>NZ_CP016552|6|6|1831685-1831982|CRISPRCasFinder
AGTTTCAGTTCCTCATGGGTACGATAAAAAC	GTTCATCATCGTTGACGGGTTCCATCGGTACACGATTT
TGTTTCAATCCCTCATAGGTACGATAAAAAC	ACAAAGGAACATGGATAGGATTTGCCTCCATGCGT
TGTTTCAATCCCTCATAGGTACGATAAAAAC	AAGACCCATTTGCAAATCGCCCTGGCTAAACGGCTCA
TGTTTCAATCCCTCATAGGTACGATAAAAAC	CATCACCCATCTCTTCAACTTTTCCGAGAACTC
AGTTTCAATCCCTCATAGGTACGATAAAAAC

>NZ_CP016552|6|3|1831686-1831982|CRT
GTTTCAGTTCCTCATGGGTACGATAAAAAC	GTTCATCATCGTTGACGGGTTCCATCGGTACACGATTTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ACAAAGGAACATGGATAGGATTTGCCTCCATGCGTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	AAGACCCATTTGCAAATCGCCCTGGCTAAACGGCTCAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CATCACCCATCTCTTCAACTTTTCCGAGAACTCA
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NZ_CP016552|6|5|1831754-1831982|PILER-CR
TGTTTCAATCCCTCATAGGTACGATAAAAAC	ACAAAGGAACATGGATAGGATTTGCCTCCATGCGT
TGTTTCAATCCCTCATAGGTACGATAAAAAC	AAGACCCATTTGCAAATCGCCCTGGCTAAACGGCTCA
TGTTTCAATCCCTCATAGGTACGATAAAAAC	CATCACCCATCTCTTCAACTTTTCCGAGAACTC
AGTTTCAATCCCTCATAGGTACGATAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_020755308.1\|1819495_1819801_-\|urease-subunit-gamma	unknown	unknown	gnl\|CDD\|183913
NZ_CP016552.1\|WP_095859461.1\|1820565_1821330_-\|urea-ABC-transporter-ATP-binding-protein-UrtD	unknown	unknown	gnl\|CDD\|274568
NZ_CP016552.1\|WP_095860223.1\|1821304_1822363_-\|urea-ABC-transporter-permease-subunit-UrtC	unknown	unknown	gnl\|CDD\|132449
NZ_CP016552.1\|WP_095859470.1\|1840709_1841870_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP016552.1\|WP_047819314.1\|1828403_1829420_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP016552.1\|WP_095859466.1\|1835685_1837212_-\|transporter	unknown	unknown	gnl\|CDD\|225870
NZ_CP016552.1\|WP_095859460.1\|1819885_1820587_-\|urea-ABC-transporter-ATP-binding-subunit-UrtE	unknown	unknown	gnl\|CDD\|274567
NZ_CP016552.1\|WP_044743595.1\|1833293_1833986_-\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP016552.1\|WP_095859468.1\|1837733_1838774_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270234
NZ_CP016552.1\|WP_095859465.1\|1833999_1835610_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP016552.1\|WP_095859464.1\|1830607_1831510_-\|transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095859463.1\|1826841_1828386_-\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP016552.1\|WP_095859462.1\|1822374_1823268_-\|urea-ABC-transporter-permease-subunit-UrtB	unknown	unknown	gnl\|CDD\|200272
NZ_CP016552.1\|WP_095859469.1\|1839153_1840002_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_050367343.1\|1823329_1824586_-\|urea-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|132448
NZ_CP016552.1\|WP_095859472.1\|1842318_1844409_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP016552.1\|WP_044743596.1\|1832164_1833100_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NZ_CP016552.1\|WP_095859471.1\|1841869_1842313_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP016552.1\|WP_095859459.1\|1819115_1819451_-\|urease-subunit-beta	unknown	unknown	gnl\|CDD\|237303
NZ_CP016552.1\|WP_095859467.1\|1837225_1837681_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_020755308.1\|1819495_1819801_-\|urease-subunit-gamma	gnl\|CDD\|183913	PRK13241, ureA, urease subunit gamma; Provisional.	6.84014e-70
NZ_CP016552.1\|WP_095859461.1\|1820565_1821330_-\|urea-ABC-transporter-ATP-binding-protein-UrtD	gnl\|CDD\|274568	TIGR03411, urea_trans_UrtD, urea ABC transporter, ATP-binding protein UrtD. Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	2.48881e-152
NZ_CP016552.1\|WP_095860223.1\|1821304_1822363_-\|urea-ABC-transporter-permease-subunit-UrtC	gnl\|CDD\|132449	TIGR03408, urea_trans_UrtC, urea ABC transporter, permease protein UrtC. Members of this protein family are ABC transporter permease proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	8.04591e-159
NZ_CP016552.1\|WP_095859470.1\|1840709_1841870_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP016552.1\|WP_047819314.1\|1828403_1829420_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	5.75178e-111
NZ_CP016552.1\|WP_095859466.1\|1835685_1837212_-\|transporter	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_CP016552.1\|WP_095859460.1\|1819885_1820587_-\|urea-ABC-transporter-ATP-binding-subunit-UrtE	gnl\|CDD\|274567	TIGR03410, urea_trans_UrtE, urea ABC transporter, ATP-binding protein UrtE. Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	1.9177e-130
NZ_CP016552.1\|WP_044743595.1\|1833293_1833986_-\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	3.67608e-90
NZ_CP016552.1\|WP_095859468.1\|1837733_1838774_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	8.36512e-95
NZ_CP016552.1\|WP_095859465.1\|1833999_1835610_-\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	0
NZ_CP016552.1\|WP_095859464.1\|1830607_1831510_-\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	4.34358e-15
NZ_CP016552.1\|WP_095859463.1\|1826841_1828386_-\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP016552.1\|WP_095859462.1\|1822374_1823268_-\|urea-ABC-transporter-permease-subunit-UrtB	gnl\|CDD\|200272	TIGR03409, urea_trans_UrtB, urea ABC transporter, permease protein UrtB. Members of this protein family are ABC transporter permease proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	3.84721e-146
NZ_CP016552.1\|WP_095859469.1\|1839153_1840002_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	3.89435e-09
NZ_CP016552.1\|WP_050367343.1\|1823329_1824586_-\|urea-ABC-transporter-substrate-binding-protein	gnl\|CDD\|132448	TIGR03407, urea_ABC_UrtA, urea ABC transporter, urea binding protein. Members of this protein family are ABC transporter substrate-binding proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. Members of this protein family tend to have the twin-arginine signal for Sec-independent transport across the plasma membrane. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_CP016552.1\|WP_095859472.1\|1842318_1844409_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	2.9929e-66
NZ_CP016552.1\|WP_044743596.1\|1832164_1833100_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	7.82496e-32
NZ_CP016552.1\|WP_095859471.1\|1841869_1842313_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.04298e-57
NZ_CP016552.1\|WP_095859459.1\|1819115_1819451_-\|urease-subunit-beta	gnl\|CDD\|237303	PRK13203, ureB, urease subunit beta; Reviewed.	2.62955e-66
NZ_CP016552.1\|WP_095859467.1\|1837225_1837681_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	2.23013e-10

>NZ_CP016552.1|WP_095859464.1|1830607_1831510_-|transposase
MAKQRIDHDRLFKELLSTFFEEFLLLFFPDVYEYIDVHHLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRILPIAIFSYDEQYDEPSSLVMQFPFLTVLDFRFLTVELCKLPWRAYIRHANPVAAALLSKMGYNEDEKVDVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRHEVSQMETKEAKRVMELIVSYEQRGMEKGIQQGIEQGMKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVEMIEKVRQ
>NZ_CP016552.1|WP_047819314.1|1828403_1829420_-|LacI-family-transcriptional-regulator
MKKVTMADVAKLANVSKSTVSQYLNKRYEYMSEETRKRIAEAIEELGYQPNIIARSLKQKTTATIGVIVFNMLHMMTTQVLHAIEEECQKRGFQVIVCNSGDDPDKEKTYVDTLLAKQVDGLIVFPTGKNEDVYRRLVEERFPLVFVDRMVPGVEADSVLLDNAGAAEMAVQYFASQGRDRIAIVTPPLVSYNVPRMERLEGFRAAMEKRGFEVGDQNVIAAEPAALPGELKKRFMESERPNALFAINDLTLMGVLRFVKDAGVRVPDEVAIINIDDVPFADIYTPALTTIAQPTFAMGKKAAERVFEQMKAKKADGPRVFRFSPVLMERTSIKREKA
>NZ_CP016552.1|WP_095859463.1|1826841_1828386_-|gluconokinase
MAIYGDVVIGIDIGTTSTKAVVFDGRGKVLASHAVDYPIIQPHPGFAEQDPDELFAAVVQAVGAVTVRHGIRPEQVKAMGLSAAMHSIMALDESGRPLTRLLIWADNRSVAQTERLWKEQNGLDIYRRTGTPIHPMSPLSKLLWLKEEQPDVFQQARRFVSVKDYVLHRLYGDYVADHSMASATGLFRLDTLDWDEEALALVGIRRDQLPWLVPATHIMTGMKREWAEKMGVAPDVPVVVGASDGVLANVGVGAVLPGEAAITIGTSGAVRTIATKPTTDEKGRTFCYALTPGYWVVGGPTNNGGILLRWLRDEFGAHEREVAKKLGIDPYELLTKYAERVPPGSEGLVFLPFLSGERAPYWNANARGTFFGLGLHHKREHFIRAVMEGVCFSILSVALAIRDVTGPMSEIRVSGGFAKSPFWRQMLSDMLGKPLIVPQTHEASALGAAAVALYALGELPSLETVKTWIDTTARHEPKEEHTLIYAELFDLYARLYERLKEEFDIIAAFQRRSG
>NZ_CP016552.1|WP_050367343.1|1823329_1824586_-|urea-ABC-transporter-substrate-binding-protein
MKPAFMWKLWLLLCVSVFALGGCAASSAVDQAKNENQNDSSSAGKEGDVVKVGILHSLSGTMAISEVSLRDAELMAIEEINASGGLLSKKIEPVVEDGASDWPTFAEKAKKLLQKDQVAAIFGGWTSASRKAMLPVVEQNNGLLWYPVQYEGMESSPNIFYTGATTNQQIVPAVSWLLKNRGKTFFLLGSDYVFPRTANKIIKAQLKAEGGQVVGEEYTPLGHTDYSTIISKIKQVKPAVVFNTLNGDSNVAFFKQLKDAGITPKDVTVMSVSIAEEEIRGIGPDVLAGHLAVWNYFQTTDTPENKAFVQKYKEKYGQDRVTDDPIEAAYTAVHLWAEAVKKAGSFDVDQVKKAAAGLEYKAPEGTVKIDGETQHLWKTVRIGEIQADGQFKELWNSGQPVKPDPYLKSYPWGKGLSE
>NZ_CP016552.1|WP_095859462.1|1822374_1823268_-|urea-ABC-transporter-permease-subunit-UrtB
MFIDQLFNGLSVGSILLLIAIGLAITFGLMGVINMANGELMMVGAYTTYVIQQIFAHHAPQSAGMYFVIAIPSSFLIAALLGWGLEKSLIRHLYHRPLDSLLATWGISLILQQTARLIFGAPNVAVVPPSWLDGGIRLFGAVFPYKRLFILCLVLAIVFFLYMYLTRTRAGRRIQAVTMNRSMAACLGIATQKVDAYSFAIGSGLAGVAGCALTLLGPIGPTIGTYYIVDAFMVVILGGVGKLAGTLLGAFGLGLISTFVEYSTSATIAKVIVFVLIIAFLQWKPSGLLSLRTRSLD
>NZ_CP016552.1|WP_095860223.1|1821304_1822363_-|urea-ABC-transporter-permease-subunit-UrtC
MVNKRWGYWLFFVALFLAPFYLTEFRLSLLGKFLCFAIVAVGISLIWGYTGILSLGHGVYFGLGAYCMAMYLKLEVSQGHLPDFMEWSSVRELPWFWKPFAHPVVAVAAAIALPTLLAALLSYFTFKNRIQGVYFSLLSQAVVVVFVTLFIGKQEWTGGTNGLTNFSTVFGFSLSSPLTQIVLYWLTAAVLALIFVMTRRLTTGRLGKVLIAIRDAENRVRFLGFNPTVYKVFVYSLSAAFAGVAGALFVLQVGLISPEMMGIIPSIEMVLWAAVGGRHSLMGAIMGAIVMNTAKSFLSENYPDLWLLLLGALFVVVVLFVPKGLAGIYESLAAVRIKAKRGHECEARVDVS
>NZ_CP016552.1|WP_095859461.1|1820565_1821330_-|urea-ABC-transporter-ATP-binding-protein-UrtD
MKPVLMCRDVVVDFDGFRALQGVDLAIYPHEVRFLIGPNGAGKTTLLDVICGRTRATDGRVLFFSHDITKRPEYEIVQMGIARKFQSPSIFPFLTVWENMELAMRQDRRLRSVLRAKLTGEEKEMMAAQLEKIGLLDERHRLAGSLSHGQKQWLEIGMQLIQRPQLLLLDEPIAGMSAAERERTGEWLHEMAEHCAVIIVEHDMDFVRRYSKQVTVMHEGKVLCEGSMDEVQQNEQVIDVYLGRGKNACCASGM
>NZ_CP016552.1|WP_095859460.1|1819885_1820587_-|urea-ABC-transporter-ATP-binding-subunit-UrtE
MLRLRDVTAGYDGSVVLDHVDMDVPLGRVTAVLGRNGVGKTTLMKTIIGLIRPMSGVVEWEGEDITRWPPERRARAGIGYVPQGREIFSALTVEENILLGLEAQAEKVRPQPTLDEMYALFPILKEMRQRKGGDLSGGQQQQLAIARALAGRPKLLLLDEPMEGIQPSIVALIHDVIMKIAKEKQVGIILVEHNVELAFSCADRFYILDRGAVVAKGDVDGADLTYIQSFLAV
>NZ_CP016552.1|WP_020755308.1|1819495_1819801_-|urease-subunit-gamma
MKLTPREQEKLLIVVAADLARRRKERGLKLNYPEAVALITYELMEGARDGRTVAELMQYGATILTRDDVMEGVADMIDEIQVEATFPDGTKLVTVHQPIRS
>NZ_CP016552.1|WP_095859459.1|1819115_1819451_-|urease-subunit-beta
MIPGEYRLRDEPIACNRQKPVTKLTVINSGDRPVQVGSHFHFFEVNSFLEFDRQAAYGKHLNIPAGTAVRFEPGDAKQVELVPFSGKRRVYGLNNMVNGPLDDNGKEGARE
>NZ_CP016552.1|WP_044743596.1|1832164_1833100_-|AEC-family-transporter
MAVFSGILLQVMVPMLLIVGLGAGLHRFFHLDLNTLSKLNMYVLLPAVAFINVYDSELNGKVLAAILAFLLLQNSGLIVLSMMMAKLFKLERSLSAVFQNTIVLNNSGNFGIPVSQLVFHQHPLGATIQIMVTIFQNFLTNTYGVYQFVSGNGKREKWTAEIWKNPVLHALLLGVVCRWLHVPIPSFLWTPLQRVADAFLAIALFTLGAQIAYARFTALPPLVYVSVFGRLILSPLLAGSLIFLLGMDGVTAQALLIASSYPCSRNTALYALEYDCHPDYAAQAVLVSTLLSAITVTGTVYAARLLFPIGG
>NZ_CP016552.1|WP_044743595.1|1833293_1833986_-|response-regulator
MLPIRVLIIEDDRRIAEINRRFVEKVNGYEVVGIATNAEEARELTEVLRPDMLLLDVYFPDMNGLSFLKWVRERFSDIDIIMITAAREVEALKQALHGGVFDYIIKPIMFDRFADTLHRYKEYYDKMQRWVKEKEWIGQEEVDALMGREVSVKEQPMLPKGIQPLTLEKVLGVVRQCAEGITAEEVGRQIGTSRTTARRYLEYLVSVGQVTADIAYGSVGRPERVYKKKM
>NZ_CP016552.1|WP_095859465.1|1833999_1835610_-|sensor-histidine-kinase
MKLQTRLMMIICSLLLFVIVFLTFLFQHMFAETIKQQIGMRALNVSETVASTPLVREAFRDPDPSVRLQPFAEYIRRKTGAEYVVIGNRQGIRYAHPLPDRIGKPMVGGDNGEVLKGKAIISEAVGSLGPAIRGKAPVLDENGQVIGIVSVGFLLEDIRQTVWSYSLKIFLFSVLALLLGAVGAMAIARAVKKSIHGLEPEEIGLLYQEKQAILEAIREGMVAINQEGTITMVNQTALKLLGYENERDVLGMPILQLIPHSRLPEVIRTGQAEFDDEMVLGEETVIVNRIPIKDKQGRVIGAVSTFRNKSELYRLTKELSQLRSYADALRAQTHEFSNKLYLISGLIQLESYEEALELIAKETDLQQNIVRFVMKEIPDPIIGGLLIGKFNRANELKIVFEIDRESSFRDVPPWMDRDHLVTIIGNVVDNAMEAVLHNGKEEKRVAVFLTDLGNDLIIEVEDNGLGIDPAVAERIYERGFSTKAAGGRGYGLDLVNRALTMLGGQMTYRSEQGAGTVFTIMIPKRPAHVGRQDRQG
>NZ_CP016552.1|WP_095859466.1|1835685_1837212_-|transporter
MDTLSFLFDGFQTALQPHNLLFAFIGVLIGTAVGVLPGIGPMSGVALLIPVTASMTSGLSPEQAAASSIILLAGVYYGAMYGGSTTSILLNTPGESSSVVTTLDGYQMARQGRAGAALAIAAIGSFVAGIVSLIGLVLLAEPLSNVALKFGPAEYFSLMLLGLAAVSGLAGKSMTKAWIMTIFGLLLSTIGLDNVSGVARFTYNISYLYGGLEFLTVAVGLFALGEVFKSILHNEMNSGEIAKIGRVLPTKADLKESAGPIARGSLLGFFIGVLPGAGATLASFFSYILEKKISKHPEKFGQGTIAGVAAPESANNGASGGAMIPLLTLGIPGSGTTAILMGALIMYNVQPGPLLFDEHPAVAWGLIASMFIGNVMLLILNMPLVKLFAKIIQTPTKYLLPLIIAISVFGVYAVQVTTFDVFLLLAFGLLGYWLAEHDYPLAPLVLGLVLGPMIENNMRRALTASNGDYLVFVEKPISLVLLVIALLWIAVPFFMKLRGKTVIVNEDM
>NZ_CP016552.1|WP_095859467.1|1837225_1837681_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MNKTADRISAVAFLAVGALFMVESLRISKSAYGSAVGPNVFPFLLGLVLVLLSIKLLFETRNYSGATGEKLPRQYKKFLVIFIAAIFYAALLETVGYVITTFLFLVIGFQTMEKGALWKSIAIAAGFSLGVYGLYVKLLQGTLPSWPIWFQ
>NZ_CP016552.1|WP_095859468.1|1837733_1838774_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKKTKWWGLLAAGMMTLALAACGGNESAGSKSSGSNSGSSASNYPTKPITIVAPSGAGGGWDLTARAVTKVLDETGLVKQTMTVENKPGGGGAVFMAEYATQDVKNDYKLFVNSPPIIINNLKKEGNSPFGYKDTTPLAQLTKDFGAIVVKADSKFQTLTDLLNAIKQNAKSVTVAGGSAPGSMDHLVAILPIYKSGIDPKSVKYVSYDGGGEAMAALLGGNADVIATDASSVGEYLKAGKVRVLAVSAPERLGGVLKDVPTMKELGVDAEFTIWRGVFGPKEMSSEAKAFWEETLKKLSEHEKWKEEMQKQGWEAEYRDSEEFTKFLQEQEQQIGDLLKSLGMHK
>NZ_CP016552.1|WP_095859469.1|1839153_1840002_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIQTFFEEFLLLFFPDMHEHIDFRHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVENQSYVQPSFPERMFIYFSRLFEKYRTRIVPIAVFSYEALREEPSVFSIEFPFGDVLQFRFFPVELRKKHWRDYIRHDNPIAAALLSKMGYTESEKVELKKEFLRMLVRLELDEARQRLLLGFFETYVKLSEEEEQQLQREVRAMETKEKEQVLELIISYEQKGRKQGIKQGMKQLIRNMARKGMKAEDIARLVDLPEQDVRELLEE
>NZ_CP016552.1|WP_095859470.1|1840709_1841870_-|mannitol-1-phosphate-5-dehydrogenase
MQAVHFGAGNIGRGFIGSLLAASGYKVVFVDVNEQIVRLLKERGEYRVIVAGEQREEQWVRGVSALNSQTEREQVIAAIAAADLVTTAVGPHILPAIAPLVADGLKQRLGVQQTPLHVIACENMIGGTETLKQYVFAHLSEAEQQLAGESVGFLNCAVDRIVPNQTNDDPLAVTVEPFFEWAIETRNVIGAVPPIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYLKGCETVQDAMKDSAIRADVEQALSESGAVLVKKHGWKADEHRAYIETTIGRFMNPALSDDIIRVARSPIRKLGPNDRLVAPAVQYCALFGNAPQGLAKGIAALLRFDDARDAEAAALQQTIAQHGIEGALRQYAGLESAHPLVAAVKDEYGRMEKNKN
>NZ_CP016552.1|WP_095859471.1|1841869_1842313_-|PTS-sugar-transporter-subunit-IIA
MVTHSILNKENIVLNAQPKTKEEAIRLAGEVLVKQGYVDPAYVDAMLEREELTSTYIGNNVAIPHGTEAAKALVKQSGISIVQVPGGVDFGGSNTALIVIGIAGKDGEHLDILSKLALICAEADNVEAMANAKTEEDILALLHEVNG
>NZ_CP016552.1|WP_095859472.1|1842318_1844409_-|BglG-family-transcription-antiterminator
MYVSARERKLLERLLASDRDLTVGELAEELNVSARTVHRDLQGLESVLRRYGLELVKKAGVGIRLVGKEENKQALTTELLRLSHHEYTPEERQLMILIALLEAAEPVKLVSLANDLNVTVATVSLDLDKLEQTVGAYGLSLIRKRGYGVELAGSESAKRRLISDLLFRHVDEHEFLALMKETIQRRADEPLDTMAEKLLGFVDRKKLAIIERQIEQVKETFPFTMADSSYIAFVVHLALAIERIQRGDAIHFDPHDLQALQATNEYEIARALAESLEKVFGVDIPNEEIGYMTMHLMGAKWRSRQGTMMEETSLAVGMKAQQLIRFVSRELGIDLSADRTLYEDLIVHLKPALYRLEHGMGVSNPLLAQIKRDYAELFAIVADGARQLFGDIPVPDEEIGYLVLHFASALMRERKGWRVLVICSSGLGTAKILATRLKKEIPDIVSLEQASVFEWKEKDASAYDLVVSTVPLADEGGPYFTVSPMLTEEEARAIREFLERKSAAEKRMRKESTAQRNRPALEAMKAVRRISETIVHLLDGFSLEVVKGRSVHELLADACRRLERSGVIVDADVVIEELRRRESLGGLGIPGTTLALYHARSFAVLRPSLTMYRLDAPQTVPGMDGEPMEINTVVLLLGPSDADKEMLAVLSEVSSLLVKDEQSLAVLAHGGEEEVYSLVSVHLEQFFDHYWTSTKE

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Crispr_ID: NZ_CP016552_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_7

1840103-1840529

TypeV

Consensus_repeat	Method
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRISPRCasFinder
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR

6 spacers

cas14k

The CRISPR arrays of NZ_CP016552_7

>merge|NZ_CP016552|7|1840103-1840529|CRISPRCasFinder,CRT,PILER-CR
GCTTCAGTCCCCCACAGGTACGATAAAAACGTATTCCTGTACCACGGATTTAACTGTTGAACAGATGTTTCAATCCCTCATAGGTACGATAAAAACATGGACATAAGAACATACTTTCTTCTTGCGCGAATGTAGTTTCAATCCCTCATAGGTACGATAAAAACTCAAGTTGAGAATGAAAAATTATCCATTTTACTAGAGTTTCAATCCCTCATAGGTACGATAAAAACGGCTGTCGCTATTCCTGACGGTGTGTATCTCAAATGTTTCAATCCCTCATAGGTACGATAAAAACCTGGAGTTGGTGGAGAATATTGTGGCCGTCCATTAAAGTTTCAATCCCTCATAGGTACGATAAAAACGAAGGCATGGCGGAGATCGTGCAAGGACAAGCCTAGTTTCAATCCCTCATAGGTACGATAAAAAC

>NZ_CP016552|7|7|1840103-1840529|CRISPRCasFinder
GCTTCAGTCCCCCACAGGTACGATAAAAAC	GTATTCCTGTACCACGGATTTAACTGTTGAACAGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGGACATAAGAACATACTTTCTTCTTGCGCGAATGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCAAGTTGAGAATGAAAAATTATCCATTTTACTAGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCTGTCGCTATTCCTGACGGTGTGTATCTCAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CTGGAGTTGGTGGAGAATATTGTGGCCGTCCATTAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAAGGCATGGCGGAGATCGTGCAAGGACAAGCCTA
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NZ_CP016552|7|4|1840103-1840529|CRT
GCTTCAGTCCCCCACAGGTACGATAAAAAC	GTATTCCTGTACCACGGATTTAACTGTTGAACAGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGGACATAAGAACATACTTTCTTCTTGCGCGAATGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCAAGTTGAGAATGAAAAATTATCCATTTTACTAGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCTGTCGCTATTCCTGACGGTGTGTATCTCAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CTGGAGTTGGTGGAGAATATTGTGGCCGTCCATTAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAAGGCATGGCGGAGATCGTGCAAGGACAAGCCTA
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NZ_CP016552|7|6|1840169-1840529|PILER-CR
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGGACATAAGAACATACTTTCTTCTTGCGCGAATGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCAAGTTGAGAATGAAAAATTATCCATTTTACTAGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCTGTCGCTATTCCTGACGGTGTGTATCTCAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CTGGAGTTGGTGGAGAATATTGTGGCCGTCCATTAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAAGGCATGGCGGAGATCGTGCAAGGACAAGCCTA
GTTTCAATCCCTCATAGGTACGATAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_095859475.1\|1846267_1846771_-\|DUF3368-domain-containing-protein	unknown	unknown	gnl\|CDD\|225269
NZ_CP016552.1\|WP_095859477.1\|1848925_1850389_-\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NZ_CP016552.1\|WP_013523968.1\|1846763_1847054_-\|UPF0175-family-protein	unknown	unknown	gnl\|CDD\|377095
NZ_CP016552.1\|WP_158522911.1\|1853782_1853941_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_047819314.1\|1828403_1829420_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP016552.1\|WP_095859466.1\|1835685_1837212_-\|transporter	unknown	unknown	gnl\|CDD\|225870
NZ_CP016552.1\|WP_095859476.1\|1847489_1848737_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	gnl\|CDD\|366606
NZ_CP016552.1\|WP_095859470.1\|1840709_1841870_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP016552.1\|WP_044743595.1\|1833293_1833986_-\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP016552.1\|WP_095859468.1\|1837733_1838774_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270234
NZ_CP016552.1\|WP_095859465.1\|1833999_1835610_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP016552.1\|WP_095859464.1\|1830607_1831510_-\|transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095859463.1\|1826841_1828386_-\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP016552.1\|WP_095859478.1\|1850590_1851778_-\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341473
NZ_CP016552.1\|WP_095859469.1\|1839153_1840002_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NZ_CP016552.1\|WP_095859472.1\|1842318_1844409_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP016552.1\|WP_044743596.1\|1832164_1833100_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NZ_CP016552.1\|WP_095859471.1\|1841869_1842313_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP016552.1\|WP_095859474.1\|1844677_1846126_-\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP016552.1\|WP_095859467.1\|1837225_1837681_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_095859475.1\|1846267_1846771_-\|DUF3368-domain-containing-protein	gnl\|CDD\|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.56045e-32
NZ_CP016552.1\|WP_095859477.1\|1848925_1850389_-\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_CP016552.1\|WP_013523968.1\|1846763_1847054_-\|UPF0175-family-protein	gnl\|CDD\|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	2.75843e-16
NZ_CP016552.1\|WP_047819314.1\|1828403_1829420_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	5.75178e-111
NZ_CP016552.1\|WP_095859466.1\|1835685_1837212_-\|transporter	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_CP016552.1\|WP_095859476.1\|1847489_1848737_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|366606	pfam01385, OrfB_IS605, Probable transposase. This family includes IS891, IS1136 and IS1341. DUF1225, pfam06774, has now been merged into this family.	2.15773e-40
NZ_CP016552.1\|WP_095859470.1\|1840709_1841870_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP016552.1\|WP_044743595.1\|1833293_1833986_-\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	3.67608e-90
NZ_CP016552.1\|WP_095859468.1\|1837733_1838774_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	8.36512e-95
NZ_CP016552.1\|WP_095859465.1\|1833999_1835610_-\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	0
NZ_CP016552.1\|WP_095859464.1\|1830607_1831510_-\|transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	4.34358e-15
NZ_CP016552.1\|WP_095859463.1\|1826841_1828386_-\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP016552.1\|WP_095859478.1\|1850590_1851778_-\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341473	cd08194, Fe-ADH-like, Iron-containing alcohol dehydrogenases-like. This family contains iron-containing alcohol dehydrogenase (Fe-ADH) most of which have not been characterized. Their specific function is unknown. The protein structure represents a dehydroquinate synthase-like fold and belongs to the alcohol dehydrogenase-like superfamily. It is distinct from other alcohol dehydrogenases which contain different protein domains. Alcohol dehydrogenase catalyzes the reduction of acetaldehyde to alcohol with NADP as cofactor. Its activity requires iron ions.	0
NZ_CP016552.1\|WP_095859469.1\|1839153_1840002_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	3.89435e-09
NZ_CP016552.1\|WP_095859472.1\|1842318_1844409_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	2.9929e-66
NZ_CP016552.1\|WP_044743596.1\|1832164_1833100_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	7.82496e-32
NZ_CP016552.1\|WP_095859471.1\|1841869_1842313_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.04298e-57
NZ_CP016552.1\|WP_095859474.1\|1844677_1846126_-\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP016552.1\|WP_095859467.1\|1837225_1837681_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	2.23013e-10

>NZ_CP016552.1|WP_095859469.1|1839153_1840002_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIQTFFEEFLLLFFPDMHEHIDFRHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVENQSYVQPSFPERMFIYFSRLFEKYRTRIVPIAVFSYEALREEPSVFSIEFPFGDVLQFRFFPVELRKKHWRDYIRHDNPIAAALLSKMGYTESEKVELKKEFLRMLVRLELDEARQRLLLGFFETYVKLSEEEEQQLQREVRAMETKEKEQVLELIISYEQKGRKQGIKQGMKQLIRNMARKGMKAEDIARLVDLPEQDVRELLEE
>NZ_CP016552.1|WP_095859468.1|1837733_1838774_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKKTKWWGLLAAGMMTLALAACGGNESAGSKSSGSNSGSSASNYPTKPITIVAPSGAGGGWDLTARAVTKVLDETGLVKQTMTVENKPGGGGAVFMAEYATQDVKNDYKLFVNSPPIIINNLKKEGNSPFGYKDTTPLAQLTKDFGAIVVKADSKFQTLTDLLNAIKQNAKSVTVAGGSAPGSMDHLVAILPIYKSGIDPKSVKYVSYDGGGEAMAALLGGNADVIATDASSVGEYLKAGKVRVLAVSAPERLGGVLKDVPTMKELGVDAEFTIWRGVFGPKEMSSEAKAFWEETLKKLSEHEKWKEEMQKQGWEAEYRDSEEFTKFLQEQEQQIGDLLKSLGMHK
>NZ_CP016552.1|WP_095859467.1|1837225_1837681_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MNKTADRISAVAFLAVGALFMVESLRISKSAYGSAVGPNVFPFLLGLVLVLLSIKLLFETRNYSGATGEKLPRQYKKFLVIFIAAIFYAALLETVGYVITTFLFLVIGFQTMEKGALWKSIAIAAGFSLGVYGLYVKLLQGTLPSWPIWFQ
>NZ_CP016552.1|WP_095859466.1|1835685_1837212_-|transporter
MDTLSFLFDGFQTALQPHNLLFAFIGVLIGTAVGVLPGIGPMSGVALLIPVTASMTSGLSPEQAAASSIILLAGVYYGAMYGGSTTSILLNTPGESSSVVTTLDGYQMARQGRAGAALAIAAIGSFVAGIVSLIGLVLLAEPLSNVALKFGPAEYFSLMLLGLAAVSGLAGKSMTKAWIMTIFGLLLSTIGLDNVSGVARFTYNISYLYGGLEFLTVAVGLFALGEVFKSILHNEMNSGEIAKIGRVLPTKADLKESAGPIARGSLLGFFIGVLPGAGATLASFFSYILEKKISKHPEKFGQGTIAGVAAPESANNGASGGAMIPLLTLGIPGSGTTAILMGALIMYNVQPGPLLFDEHPAVAWGLIASMFIGNVMLLILNMPLVKLFAKIIQTPTKYLLPLIIAISVFGVYAVQVTTFDVFLLLAFGLLGYWLAEHDYPLAPLVLGLVLGPMIENNMRRALTASNGDYLVFVEKPISLVLLVIALLWIAVPFFMKLRGKTVIVNEDM
>NZ_CP016552.1|WP_095859465.1|1833999_1835610_-|sensor-histidine-kinase
MKLQTRLMMIICSLLLFVIVFLTFLFQHMFAETIKQQIGMRALNVSETVASTPLVREAFRDPDPSVRLQPFAEYIRRKTGAEYVVIGNRQGIRYAHPLPDRIGKPMVGGDNGEVLKGKAIISEAVGSLGPAIRGKAPVLDENGQVIGIVSVGFLLEDIRQTVWSYSLKIFLFSVLALLLGAVGAMAIARAVKKSIHGLEPEEIGLLYQEKQAILEAIREGMVAINQEGTITMVNQTALKLLGYENERDVLGMPILQLIPHSRLPEVIRTGQAEFDDEMVLGEETVIVNRIPIKDKQGRVIGAVSTFRNKSELYRLTKELSQLRSYADALRAQTHEFSNKLYLISGLIQLESYEEALELIAKETDLQQNIVRFVMKEIPDPIIGGLLIGKFNRANELKIVFEIDRESSFRDVPPWMDRDHLVTIIGNVVDNAMEAVLHNGKEEKRVAVFLTDLGNDLIIEVEDNGLGIDPAVAERIYERGFSTKAAGGRGYGLDLVNRALTMLGGQMTYRSEQGAGTVFTIMIPKRPAHVGRQDRQG
>NZ_CP016552.1|WP_044743595.1|1833293_1833986_-|response-regulator
MLPIRVLIIEDDRRIAEINRRFVEKVNGYEVVGIATNAEEARELTEVLRPDMLLLDVYFPDMNGLSFLKWVRERFSDIDIIMITAAREVEALKQALHGGVFDYIIKPIMFDRFADTLHRYKEYYDKMQRWVKEKEWIGQEEVDALMGREVSVKEQPMLPKGIQPLTLEKVLGVVRQCAEGITAEEVGRQIGTSRTTARRYLEYLVSVGQVTADIAYGSVGRPERVYKKKM
>NZ_CP016552.1|WP_044743596.1|1832164_1833100_-|AEC-family-transporter
MAVFSGILLQVMVPMLLIVGLGAGLHRFFHLDLNTLSKLNMYVLLPAVAFINVYDSELNGKVLAAILAFLLLQNSGLIVLSMMMAKLFKLERSLSAVFQNTIVLNNSGNFGIPVSQLVFHQHPLGATIQIMVTIFQNFLTNTYGVYQFVSGNGKREKWTAEIWKNPVLHALLLGVVCRWLHVPIPSFLWTPLQRVADAFLAIALFTLGAQIAYARFTALPPLVYVSVFGRLILSPLLAGSLIFLLGMDGVTAQALLIASSYPCSRNTALYALEYDCHPDYAAQAVLVSTLLSAITVTGTVYAARLLFPIGG
>NZ_CP016552.1|WP_095859464.1|1830607_1831510_-|transposase
MAKQRIDHDRLFKELLSTFFEEFLLLFFPDVYEYIDVHHLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRILPIAIFSYDEQYDEPSSLVMQFPFLTVLDFRFLTVELCKLPWRAYIRHANPVAAALLSKMGYNEDEKVDVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRHEVSQMETKEAKRVMELIVSYEQRGMEKGIQQGIEQGMKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVEMIEKVRQ
>NZ_CP016552.1|WP_047819314.1|1828403_1829420_-|LacI-family-transcriptional-regulator
MKKVTMADVAKLANVSKSTVSQYLNKRYEYMSEETRKRIAEAIEELGYQPNIIARSLKQKTTATIGVIVFNMLHMMTTQVLHAIEEECQKRGFQVIVCNSGDDPDKEKTYVDTLLAKQVDGLIVFPTGKNEDVYRRLVEERFPLVFVDRMVPGVEADSVLLDNAGAAEMAVQYFASQGRDRIAIVTPPLVSYNVPRMERLEGFRAAMEKRGFEVGDQNVIAAEPAALPGELKKRFMESERPNALFAINDLTLMGVLRFVKDAGVRVPDEVAIINIDDVPFADIYTPALTTIAQPTFAMGKKAAERVFEQMKAKKADGPRVFRFSPVLMERTSIKREKA
>NZ_CP016552.1|WP_095859463.1|1826841_1828386_-|gluconokinase
MAIYGDVVIGIDIGTTSTKAVVFDGRGKVLASHAVDYPIIQPHPGFAEQDPDELFAAVVQAVGAVTVRHGIRPEQVKAMGLSAAMHSIMALDESGRPLTRLLIWADNRSVAQTERLWKEQNGLDIYRRTGTPIHPMSPLSKLLWLKEEQPDVFQQARRFVSVKDYVLHRLYGDYVADHSMASATGLFRLDTLDWDEEALALVGIRRDQLPWLVPATHIMTGMKREWAEKMGVAPDVPVVVGASDGVLANVGVGAVLPGEAAITIGTSGAVRTIATKPTTDEKGRTFCYALTPGYWVVGGPTNNGGILLRWLRDEFGAHEREVAKKLGIDPYELLTKYAERVPPGSEGLVFLPFLSGERAPYWNANARGTFFGLGLHHKREHFIRAVMEGVCFSILSVALAIRDVTGPMSEIRVSGGFAKSPFWRQMLSDMLGKPLIVPQTHEASALGAAAVALYALGELPSLETVKTWIDTTARHEPKEEHTLIYAELFDLYARLYERLKEEFDIIAAFQRRSG
>NZ_CP016552.1|WP_095859470.1|1840709_1841870_-|mannitol-1-phosphate-5-dehydrogenase
MQAVHFGAGNIGRGFIGSLLAASGYKVVFVDVNEQIVRLLKERGEYRVIVAGEQREEQWVRGVSALNSQTEREQVIAAIAAADLVTTAVGPHILPAIAPLVADGLKQRLGVQQTPLHVIACENMIGGTETLKQYVFAHLSEAEQQLAGESVGFLNCAVDRIVPNQTNDDPLAVTVEPFFEWAIETRNVIGAVPPIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYLKGCETVQDAMKDSAIRADVEQALSESGAVLVKKHGWKADEHRAYIETTIGRFMNPALSDDIIRVARSPIRKLGPNDRLVAPAVQYCALFGNAPQGLAKGIAALLRFDDARDAEAAALQQTIAQHGIEGALRQYAGLESAHPLVAAVKDEYGRMEKNKN
>NZ_CP016552.1|WP_095859471.1|1841869_1842313_-|PTS-sugar-transporter-subunit-IIA
MVTHSILNKENIVLNAQPKTKEEAIRLAGEVLVKQGYVDPAYVDAMLEREELTSTYIGNNVAIPHGTEAAKALVKQSGISIVQVPGGVDFGGSNTALIVIGIAGKDGEHLDILSKLALICAEADNVEAMANAKTEEDILALLHEVNG
>NZ_CP016552.1|WP_095859472.1|1842318_1844409_-|BglG-family-transcription-antiterminator
MYVSARERKLLERLLASDRDLTVGELAEELNVSARTVHRDLQGLESVLRRYGLELVKKAGVGIRLVGKEENKQALTTELLRLSHHEYTPEERQLMILIALLEAAEPVKLVSLANDLNVTVATVSLDLDKLEQTVGAYGLSLIRKRGYGVELAGSESAKRRLISDLLFRHVDEHEFLALMKETIQRRADEPLDTMAEKLLGFVDRKKLAIIERQIEQVKETFPFTMADSSYIAFVVHLALAIERIQRGDAIHFDPHDLQALQATNEYEIARALAESLEKVFGVDIPNEEIGYMTMHLMGAKWRSRQGTMMEETSLAVGMKAQQLIRFVSRELGIDLSADRTLYEDLIVHLKPALYRLEHGMGVSNPLLAQIKRDYAELFAIVADGARQLFGDIPVPDEEIGYLVLHFASALMRERKGWRVLVICSSGLGTAKILATRLKKEIPDIVSLEQASVFEWKEKDASAYDLVVSTVPLADEGGPYFTVSPMLTEEEARAIREFLERKSAAEKRMRKESTAQRNRPALEAMKAVRRISETIVHLLDGFSLEVVKGRSVHELLADACRRLERSGVIVDADVVIEELRRRESLGGLGIPGTTLALYHARSFAVLRPSLTMYRLDAPQTVPGMDGEPMEINTVVLLLGPSDADKEMLAVLSEVSSLLVKDEQSLAVLAHGGEEEVYSLVSVHLEQFFDHYWTSTKE
>NZ_CP016552.1|WP_095859474.1|1844677_1846126_-|PTS-mannitol-transporter-subunit-IICB
MTHTTGNETGFRVKIQRFGSYLSGMIMPNIGAFIAWGLITALFIPTGWWPNETFAKLVGPMITYLLPLLIGYTGGKMVYDVRGGVVGATATMGVIVGSDIPMFLGAMIMGPLGGYVIKKVDGLFQGKVKQGFEMLVNNFSAGIIGGVLTLLAFKGVGPVISLISKTLAAGVEKIIDWHLLPLANLFIEPGKVLFLNNAINHGILSPLGVEQAAKTGKSILFLLETNPGPGLGILLAYWLFGKGMAKQSAPGAVIIHFLGGIHEIYFPYILMRPVLILAAMAGGVSGVFTFTILNAGLVAVPSPGSIFALLAMTPKGNYFGVLAGVFVAAAVSFLVASIFLKAAKQSEEEEELTKATEKMEQLKGKKSQVAAALQQKEAASATVAQAVPGRVKKIVFACDAGMGSSAMGASILRNKVQKAGLDIEVTNTAINQLPADADIVVTHQNLTDRAKAKLPNAYHVSVENFLNSPKYDELIEQLKKNA
>NZ_CP016552.1|WP_095859475.1|1846267_1846771_-|DUF3368-domain-containing-protein
MSRVTVNSTPIIGLSIVGQLTLLSELFDEVYVPEAVYQEIVHHHAPRHYGKEELKRLVSEGVFRLYHVKNRSLVESLYGKFHAGELEVIIGAKELGAQVVVIDEHAARSLSKQFLLRPIGTIGILILGKKNGKITEVKSLLDTLLENGFYLSRRLYQEALLLAEETP
>NZ_CP016552.1|WP_013523968.1|1846763_1847054_-|UPF0175-family-protein
MDYFQVNLPKEFLPAINELEGNTVEAKIKLSLAIGLFVGKQVTLAKAAELAGKSLGEFIDVLRSKAIPWMEYTEEHIKDDWDTVQKLSKENRDHNE
>NZ_CP016552.1|WP_095859476.1|1847489_1848737_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MYFCIKQQLNGLTKEEYLTLRELCHIAKNMYNVGLYNVRQYYFEHKEFLNYEKNYHLAKTNENYKLLNSNMAQQILKKVNEAFTSFFGLISLAKQGKYDHKAISIPKYLKKDGFHSLIIGQIRIDGNKFTIPYSRLFKKTHKPITITIPPVLLDKKIKQIEIIPKHHARFFEIQYKYEMPEDQRELNDQKALAIDLGLNNFATCVTSDGRSFIIDGRRLKSINQWFNKENARLQSIKDKQKIKGTTRKQALLAMNRNNKVNDYINKTCRYIINYCIENQIGKLVIGYAETWQRNMNLGKKTNQNFVNIPLGNIKEKLEYLCEFYGIEFLKQEESYTSQASFFDGDEIPEYNADNPKEYKFSGKRIKRGLYRTKSGKLINADVNGALNILKKSKAVDLSVLCSSGEVDTPQRIRIA
>NZ_CP016552.1|WP_095859477.1|1848925_1850389_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MSSVTETKTLKNFIGGQWVASTSGKEEIVPNPATGEVLAKVPLSSREELDAAVAAAKEAFREWRKVPVPRRARILFRYQQLLVEHWDELARLVTLENGKVYEDAYGEVQRGIECVEFAAGIPTLMMGQQLPDIATNIESGMYRYPLGVVAGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPMLANRLAELFTEAGLPAGVLNIVHGAHEVVNGILEHKDIKAVSFVGSQPVAEYVYKTAAAHGKRVQALAGAKNHSIVMPDADLDMAVTNIINAAFGSAGERCMACSVVVAVGDIADELVERLKQAADRIQIGNGLDQGVFLGPVIRESHKERTIKYIEIGEKEGALLVRDGRRDSATSGKGYFIGPTIFDHVKPGMAIWTDEIFAPVLSVVRARDLDEAIEIANRSEFANGACIYTDSAKAIRQFREEIDAGMLGVNVAVPAPMAFFPFSGYKNSFYGDLHANGRDGVEFYTRKKMVTARYQ
>NZ_CP016552.1|WP_095859478.1|1850590_1851778_-|iron-containing-alcohol-dehydrogenase
MYELLVPSRVVYGCNTFAEVGPQAKALGTKALIVSDPVMEKIGLVARCEQYLQQVGMTFAKYTGVDTEPTDVHVKEALDVCRSEQCDVIIALGGGSSIDAAKAVAVMITNEGTISDYVGNQKRFTEKPLPLIAIPTTAGTGSEVTKVTVIIDTKTDVKMMISQPALLPAVAIVDPLLTVSCPPSVTAATGVDALCHAIEAYISRRAHPVTDVLALSAIEAIVGYLRRAYENGQDIEAREKMAIAAMKAGMAFSNASVTLVHGMSRPIGALFHVPHGVSNAMLLPGVLEFTKDSAIERLAVIARIIKPPLKDVSDTEAAEALVEEVKQLCRDLHIPNMKTWGIDKTAFDKVVDKMAADALASGSPANNPKVPTHEEIVALYHYCYDYQYDTKTVSS
>NZ_CP016552.1|WP_158522911.1|1853782_1853941_+|hypothetical-protein
MNRKYGSTMGFLKLESSIKGYLSLHSRTVDLGKMADFHQPSRETRTNDKKWG

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Crispr_ID: NZ_CP016552_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_8

1955490-1957007

Unclear

Consensus_repeat	Method
CTTTAAATCCCACTCCGTTCAGATAAAAC	CRISPRCasFinder
CTTTAAATCCCACTCCGTTCAGATAAAAC	CRT
CTTTAAATCCCACTCCGTTCAGATAAAAC	PILER-CR

23 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NZ_CP016552_8

>merge|NZ_CP016552|8|1955490-1957007|CRISPRCasFinder,CRT,PILER-CR
TTTTGAATCCCACTCCGTTCAAATAAAACGACTTCGGCGATGAAATGGTTCTTTAAATCCCACTCCGTTCAGATAAAACGGAACGGTGCTCGCCAGCCTGCCGCTTGAAATCGGCTTTAAATCCCTCTCCGTTCAGATAAAACTGTTTTGCCGTATGCTTTAGGTGTTTTTGCTCTGTCTCTTTAAATCCCACTCCGTTCAGATAAAACTTGGCAAGTGCCGTTCGTTGTGACATGTCTGTTTCCACTTTAAATCCCACTCCGTTCAGATAAAACCCACATACTCGAATTGTCCGAGCCATGCTTCAAAATGCTTTAAATCCCACTCCGTTCAGATAAAACGAACATGACAACCGCTTCTTTCAAGTCACCTACAATGATCTTTAAATCCCACTCCGTTCAGATAAAACCTTTTCTCAATCGCTCGATGTCGCGTAGATACTCACTTTAAATCCCACTCCGTTCAGATAAAACGTTAAGCCAACTCCAAAACGACATCGGTGCAGGAGGCTTTAAATCCCACTCCGTTCAGATAAAACTCTGTTTTCTTGATTCGGAAAGCTGTATTGCTGCACTTTAAATCCCACTCCGTTCAGATAAAACATTTCTCCCACTCCGCGCGGTACTCCTCAAGATAACCCTTTAAATCCCACTCCGTTCAGATAAAACGATTGAGCTGATGACACATCGCCGGTTGGAAAAGTCTTTAAATCCCACTCCGTTCAGATAAAACAATCCATTTTGAGTCTTGTCGTATACCTCCAATCTTCCTTTAAATCCCACTCCGTTCAGATAAAACCGTGTACATCGGACGATGAAGCATTTGCCGCCCCTGCGCTTTAAATCCCACTCCGTTCAGATAAAACACGCCATCACCTCTCTGCCTCTTCTTTTTGGATTTCGCTTTAAATCCCACTCCGTTCAGATAAAACTATCGCGGCAGAGGGTACACTTCCGATAATTAAGAAAGCTTTAAATCCCACTCCGTTCAGATAAAACGCAACGATTGGGACTATGCGACGCGAGCGCAGGCAGCTTTAAATCCCACTCCGTTCAGATAAAACAGAAGCGCAATACAAAGCAACGATTGAACATATAGCTTTAAATCCCACTCCGTTCAGATAAAACGAGCCGAACATCTCAAAAAACGCATCGGTGCGCTCTCTTTAAATCCCACTCCGTTCAGATAAAACGATGATCTCGAATGAATATTGTAGTGGTTCACGATCCTTTAAATCCCACTCCGTTCAGATAAAACGAAGTTCGGCGCAATGACGAATTCATCCCGCCGCCTTTAAATCCCACTCCGTTCAGATAAAACGAAAATACATCGGTACCTGCCTTGAGGGCGCTTGTAGACCTTTAAATCCCACTCCGTTCAGATAAAACGATTCTTCACAGAACGAAGAACAGAAGCAAGAAAACCCTTTAAATCCCACTCCGTTCAGATAAAACTTAGATATAGTCCGCTCACAACAAGTACCAACTTCCTTTAAATCCCACTCCGTTCAGATAAAAC

>NZ_CP016552|8|8|1955490-1957007|CRISPRCasFinder
TTTTGAATCCCACTCCGTTCAAATAAAAC	GACTTCGGCGATGAAATGGTT
CTTTAAATCCCACTCCGTTCAGATAAAAC	GGAACGGTGCTCGCCAGCCTGCCGCTTGAAATCGG
CTTTAAATCCCTCTCCGTTCAGATAAAAC	TGTTTTGCCGTATGCTTTAGGTGTTTTTGCTCTGTCT
CTTTAAATCCCACTCCGTTCAGATAAAAC	TTGGCAAGTGCCGTTCGTTGTGACATGTCTGTTTCCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	CCACATACTCGAATTGTCCGAGCCATGCTTCAAAATG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAACATGACAACCGCTTCTTTCAAGTCACCTACAATGAT
CTTTAAATCCCACTCCGTTCAGATAAAAC	CTTTTCTCAATCGCTCGATGTCGCGTAGATACTCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	GTTAAGCCAACTCCAAAACGACATCGGTGCAGGAGG
CTTTAAATCCCACTCCGTTCAGATAAAAC	TCTGTTTTCTTGATTCGGAAAGCTGTATTGCTGCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	ATTTCTCCCACTCCGCGCGGTACTCCTCAAGATAACC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATTGAGCTGATGACACATCGCCGGTTGGAAAAGT
CTTTAAATCCCACTCCGTTCAGATAAAAC	AATCCATTTTGAGTCTTGTCGTATACCTCCAATCTTC
CTTTAAATCCCACTCCGTTCAGATAAAAC	CGTGTACATCGGACGATGAAGCATTTGCCGCCCCTGCG
CTTTAAATCCCACTCCGTTCAGATAAAAC	ACGCCATCACCTCTCTGCCTCTTCTTTTTGGATTTCG
CTTTAAATCCCACTCCGTTCAGATAAAAC	TATCGCGGCAGAGGGTACACTTCCGATAATTAAGAAAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GCAACGATTGGGACTATGCGACGCGAGCGCAGGCAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	AGAAGCGCAATACAAAGCAACGATTGAACATATAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAGCCGAACATCTCAAAAAACGCATCGGTGCGCTCT
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATGATCTCGAATGAATATTGTAGTGGTTCACGATC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAAGTTCGGCGCAATGACGAATTCATCCCGCCGC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAAAATACATCGGTACCTGCCTTGAGGGCGCTTGTAGAC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATTCTTCACAGAACGAAGAACAGAAGCAAGAAAACC
CTTTAAATCCCACTCCGTTCAGATAAAAC	TTAGATATAGTCCGCTCACAACAAGTACCAACTTC
CTTTAAATCCCACTCCGTTCAGATAAAAC

>NZ_CP016552|8|5|1955490-1957007|CRT
TTTTGAATCCCACTCCGTTCAAATAAAAC	GACTTCGGCGATGAAATGGTT
CTTTAAATCCCACTCCGTTCAGATAAAAC	GGAACGGTGCTCGCCAGCCTGCCGCTTGAAATCGG
CTTTAAATCCCTCTCCGTTCAGATAAAAC	TGTTTTGCCGTATGCTTTAGGTGTTTTTGCTCTGTCT
CTTTAAATCCCACTCCGTTCAGATAAAAC	TTGGCAAGTGCCGTTCGTTGTGACATGTCTGTTTCCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	CCACATACTCGAATTGTCCGAGCCATGCTTCAAAATG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAACATGACAACCGCTTCTTTCAAGTCACCTACAATGAT
CTTTAAATCCCACTCCGTTCAGATAAAAC	CTTTTCTCAATCGCTCGATGTCGCGTAGATACTCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	GTTAAGCCAACTCCAAAACGACATCGGTGCAGGAGG
CTTTAAATCCCACTCCGTTCAGATAAAAC	TCTGTTTTCTTGATTCGGAAAGCTGTATTGCTGCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	ATTTCTCCCACTCCGCGCGGTACTCCTCAAGATAACC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATTGAGCTGATGACACATCGCCGGTTGGAAAAGT
CTTTAAATCCCACTCCGTTCAGATAAAAC	AATCCATTTTGAGTCTTGTCGTATACCTCCAATCTTC
CTTTAAATCCCACTCCGTTCAGATAAAAC	CGTGTACATCGGACGATGAAGCATTTGCCGCCCCTGCG
CTTTAAATCCCACTCCGTTCAGATAAAAC	ACGCCATCACCTCTCTGCCTCTTCTTTTTGGATTTCG
CTTTAAATCCCACTCCGTTCAGATAAAAC	TATCGCGGCAGAGGGTACACTTCCGATAATTAAGAAAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GCAACGATTGGGACTATGCGACGCGAGCGCAGGCAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	AGAAGCGCAATACAAAGCAACGATTGAACATATAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAGCCGAACATCTCAAAAAACGCATCGGTGCGCTCT
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATGATCTCGAATGAATATTGTAGTGGTTCACGATC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAAGTTCGGCGCAATGACGAATTCATCCCGCCGC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAAAATACATCGGTACCTGCCTTGAGGGCGCTTGTAGAC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATTCTTCACAGAACGAAGAACAGAAGCAAGAAAACC
CTTTAAATCCCACTCCGTTCAGATAAAAC	TTAGATATAGTCCGCTCACAACAAGTACCAACTTC
CTTTAAATCCCACTCCGTTCAGATAAAAC

>NZ_CP016552|8|7|1955540-1957007|PILER-CR
CTTTAAATCCCACTCCGTTCAGATAAAAC	GGAACGGTGCTCGCCAGCCTGCCGCTTGAAATCGG
CTTTAAATCCCTCTCCGTTCAGATAAAAC	TGTTTTGCCGTATGCTTTAGGTGTTTTTGCTCTGTCT
CTTTAAATCCCACTCCGTTCAGATAAAAC	TTGGCAAGTGCCGTTCGTTGTGACATGTCTGTTTCCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	CCACATACTCGAATTGTCCGAGCCATGCTTCAAAATG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAACATGACAACCGCTTCTTTCAAGTCACCTACAATGAT
CTTTAAATCCCACTCCGTTCAGATAAAAC	CTTTTCTCAATCGCTCGATGTCGCGTAGATACTCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	GTTAAGCCAACTCCAAAACGACATCGGTGCAGGAGG
CTTTAAATCCCACTCCGTTCAGATAAAAC	TCTGTTTTCTTGATTCGGAAAGCTGTATTGCTGCA
CTTTAAATCCCACTCCGTTCAGATAAAAC	ATTTCTCCCACTCCGCGCGGTACTCCTCAAGATAACC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATTGAGCTGATGACACATCGCCGGTTGGAAAAGT
CTTTAAATCCCACTCCGTTCAGATAAAAC	AATCCATTTTGAGTCTTGTCGTATACCTCCAATCTTC
CTTTAAATCCCACTCCGTTCAGATAAAAC	CGTGTACATCGGACGATGAAGCATTTGCCGCCCCTGCG
CTTTAAATCCCACTCCGTTCAGATAAAAC	ACGCCATCACCTCTCTGCCTCTTCTTTTTGGATTTCG
CTTTAAATCCCACTCCGTTCAGATAAAAC	TATCGCGGCAGAGGGTACACTTCCGATAATTAAGAAAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GCAACGATTGGGACTATGCGACGCGAGCGCAGGCAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	AGAAGCGCAATACAAAGCAACGATTGAACATATAG
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAGCCGAACATCTCAAAAAACGCATCGGTGCGCTCT
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATGATCTCGAATGAATATTGTAGTGGTTCACGATC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAAGTTCGGCGCAATGACGAATTCATCCCGCCGC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GAAAATACATCGGTACCTGCCTTGAGGGCGCTTGTAGAC
CTTTAAATCCCACTCCGTTCAGATAAAAC	GATTCTTCACAGAACGAAGAACAGAAGCAAGAAAACC
CTTTAAATCCCACTCCGTTCAGATAAAAC	TTAGATATAGTCCGCTCACAACAAGTACCAACTTC
CTTTAAATCCCACTCCGTTCAGATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_015375155.1\|1947627_1948263_-\|3-hexulose-6-phosphate-synthase	unknown	unknown	gnl\|CDD\|132172
NZ_CP016552.1\|WP_013144993.1\|1958455_1958953_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP016552.1\|WP_015864165.1\|1951964_1952765_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|225806
NZ_CP016552.1\|WP_095859522.1\|1962756_1964553_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187796
NZ_CP016552.1\|WP_061580951.1\|1961168_1961870_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
NZ_CP016552.1\|WP_095859520.1\|1958967_1961145_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP016552.1\|WP_095859521.1\|1961872_1962760_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NZ_CP016552.1\|WP_081106643.1\|1946327_1946663_+\|bis-aminopropyl-spermidine-synthase-family-protein	unknown	unknown	gnl\|CDD\|224484
NZ_CP016552.1\|WP_095858787.1\|1950020_1950566_+\|transposase	unknown	unknown	gnl\|CDD\|379669
NZ_CP016552.1\|WP_158522912.1\|1955124_1955379_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_015864903.1\|1950718_1951972_+\|IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP016552.1\|WP_094238572.1\|1948803_1949604_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|225806
NZ_CP016552.1\|WP_095859523.1\|1964549_1965275_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187783
NZ_CP016552.1\|WP_095860231.1\|1947066_1947624_-\|6-phospho-3-hexuloisomerase	unknown	unknown	gnl\|CDD\|132171
NZ_CP016552.1\|WP_044746556.1\|1957472_1958456_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NZ_CP016552.1\|WP_095859524.1\|1965591_1968048_-\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223989
NZ_CP016552.1\|WP_013144995.1\|1957205_1957469_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP016552.1\|WP_033015496.1\|1968040_1968367_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212139
NZ_CP016552.1\|WP_095859417.1\|1954098_1954662_-\|transposase	unknown	unknown	gnl\|CDD\|379669
NZ_CP016552.1\|WP_033015477.1\|1945552_1946224_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_015375155.1\|1947627_1948263_-\|3-hexulose-6-phosphate-synthase	gnl\|CDD\|132172	TIGR03128, RuMP_HxlA, 3-hexulose-6-phosphate synthase. Members of this protein family are 3-hexulose-6-phosphate synthase (HPS), or the HPS domain of a fusion protein. This enzyme is part of the ribulose monophosphate (RuMP) pathway, which in one direction removes the toxic metabolite formaldehyde by assimilation into fructose-6-phosphate. In the other direction, in species lacking a complete pentose phosphate pathway, the RuMP pathway yields ribulose-5-phosphate, necessary for nucleotide biosynthesis, at the cost of also yielding formaldehyde. These latter species tend usually have a formaldehyde-activating enzyme to attach formaldehyde to the C1 carrier tetrahydromethanopterin. In these species, the enzyme is viewed as a lyase rather than a synthase and is called D-arabino 3-hexulose 6-phosphate formaldehyde lyase. Note that there is some overlap in specificity with the Escherichia coli enzyme 3-keto-L-gulonate 6-phosphate decarboxylase.	4.70185e-88
NZ_CP016552.1\|WP_013144993.1\|1958455_1958953_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	4.43896e-59
NZ_CP016552.1\|WP_015864165.1\|1951964_1952765_+\|AAA-family-ATPase	gnl\|CDD\|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	6.10743e-42
NZ_CP016552.1\|WP_095859522.1\|1962756_1964553_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187796	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	2.68757e-08
NZ_CP016552.1\|WP_061580951.1\|1961168_1961870_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.48442e-33
NZ_CP016552.1\|WP_095859520.1\|1958967_1961145_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	1.06121e-69
NZ_CP016552.1\|WP_095859521.1\|1961872_1962760_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	2.16374e-61
NZ_CP016552.1\|WP_081106643.1\|1946327_1946663_+\|bis-aminopropyl-spermidine-synthase-family-protein	gnl\|CDD\|224484	COG1568, COG1568, Predicted methyltransferases [General function prediction only].	2.04432e-18
NZ_CP016552.1\|WP_095858787.1\|1950020_1950566_+\|transposase	gnl\|CDD\|379669	pfam14690, zf-ISL3, zinc-finger of transposase IS204/IS1001/IS1096/IS1165.	0.00135885
NZ_CP016552.1\|WP_015864903.1\|1950718_1951972_+\|IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	4.89782e-21
NZ_CP016552.1\|WP_094238572.1\|1948803_1949604_-\|AAA-family-ATPase	gnl\|CDD\|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.22929e-41
NZ_CP016552.1\|WP_095859523.1\|1964549_1965275_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	3.06224e-26
NZ_CP016552.1\|WP_095860231.1\|1947066_1947624_-\|6-phospho-3-hexuloisomerase	gnl\|CDD\|132171	TIGR03127, RuMP_HxlB, 6-phospho 3-hexuloisomerase. Members of this protein family are 6-phospho 3-hexuloisomerase (PHI), or the PHI domain of a fusion protein. This enzyme is part of the ribulose monophosphate (RuMP) pathway, which in one direction removes the toxic metabolite formaldehyde by assimilation into fructose-6-phosphate. In the other direction, in species lacking a complete pentose phosphate pathway, the RuMP pathway yields ribulose-5-phosphate, necessary for nucleotide biosynthesis, at the cost of also yielding formaldehyde. These latter species tend usually have a formaldehyde-activating enzyme to attach formaldehyde to the C1 carrier tetrahydromethanopterin.	6.99182e-91
NZ_CP016552.1\|WP_044746556.1\|1957472_1958456_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.04403e-166
NZ_CP016552.1\|WP_095859524.1\|1965591_1968048_-\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	1.69315e-77
NZ_CP016552.1\|WP_013144995.1\|1957205_1957469_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.74906e-28
NZ_CP016552.1\|WP_095859417.1\|1954098_1954662_-\|transposase	gnl\|CDD\|379669	pfam14690, zf-ISL3, zinc-finger of transposase IS204/IS1001/IS1096/IS1165.	0.00721027
NZ_CP016552.1\|WP_033015496.1\|1968040_1968367_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|212139	cd11532, NTP-PPase_COG4997, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from archaea and bacteria. The family includes some uncharacterized hypothetical proteins from archaea and bacteria. Although their biological roles remain unclear, the family members show significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, the family contains a single MazG-like domain.	8.66741e-34

>NZ_CP016552.1|WP_158522912.1|1955124_1955379_+|hypothetical-protein
MGAQMKWIAPSWNVWPKAFRDSFLLTHESWPKVRDECERLMLGHFSSKNGDLHQRTEPTAKQAQLFAALGLEPPPKILGIHPRA
>NZ_CP016552.1|WP_095859417.1|1954098_1954662_-|transposase
MIQFHDFGIDVQTYAERGKENDFPLLKKCPHCRAKRPLHRHGYYERNALTPHGDYRIWIVRYRCRECLKTVSVLPSFLLPYVQYTRSVIWQAVKAWFETPRQGAKTKQVVFPTKEVILFYVRRFLRNLSRLHHAAARRWGIIGPVGNARTERAVWWMQTLEGRGVGSIIQDLWTNERWHPFADQIAS
>NZ_CP016552.1|WP_015864165.1|1951964_1952765_+|AAA-family-ATPase
MYKSFYSLSREPFAKETDPSEAYQGAPFQEALRALEYVKRTRGIGLLIGEPGAGKTFALRALKESLNPSLYHVVYFPLSTGGVMDFYRGLALGLGEEPKYRKVDLFRQIQQAIERLYHERRITPVFILDEMHLAKDAFLQDIAILFNFEMDSTNPFVLILAGLPHLQGKLRLNQHRPLDQRIIMRYRMGPLEKEEVAGYIEHRMKQAGAKHPIFTPSALEAIALQSRGWPRVINTLATTCLLYGYQLKKDAIDEEVVRMAAEEMGY
>NZ_CP016552.1|WP_015864903.1|1950718_1951972_+|IS481-family-transposase
MDESMRHDIALFRYGLIAPLVNGQVEPKTYLKEVSERVHHVPHQGDKRIAAKTILDWCTRYKKGGFDALKPKRRSDRGHSRRLSPDDEDHILALRKEHPTMPVTVFYEHLIEQGEIPENHISYFTIYRLLKKHNLVGKEILPMPERKRFAYDQINELWQGDLSHGPTIRVNGKAQKTFLIAYIDDCSRFVPYAQFFPSEKFDGLRIVTKEAVLRCGKPKRIYSDNGKIYRSEVLQYACAEMGITLIHTQPYDPQSKGKIERFFRTVQTRFYPLLELDPPKSLEELNERFWRWLEEEYHRKPHASLDGKTPHEVFQSQVHLVSFIEDGDWLDAIFLKREHRKVKADGTITLNKQLYEVPPRFIGQSIELRYDERGVYVYEDGRKVAEAVRVRLEDNAYVKRHRSPFAAIPAKEGEHGV
>NZ_CP016552.1|WP_095858787.1|1950020_1950566_+|transposase
MIQFHDFGIDVQTYAERGKENDFPLLTQCPHCRAKRPLHRHGYYERNALTPHGDYRIWIVRYRCRECLKTVSVLPSFLLPYFQYTLSAVWQVVKEQLGLTEGTNQAPFLPTKDGIIFYVRRFYRNLSNLHSFFARRWRIIGPIVKKEKERASWWIQTLEEHGLDSVIREMWEDGFRHPFAN
>NZ_CP016552.1|WP_094238572.1|1948803_1949604_-|AAA-family-ATPase
MYKTFYSLSREPFAKETDPSEAYQGAAFQEALRALEYVKRTRGIGLLIGEPGAGKTFTLRALKESLNPSLYHVVYFPLSTGGVMDFYRGLALGLGEEPKYRKVDLFRQIQQAIERLYHERRITPVFILDEMHLAKDAFLQDIAILFNFEMDSTNPFVLILAGLPHLQGKLRLNQHRPLDQRIIMRYRMGPLEKEEVAGYIEHRMKQAGAKHPIFTPSALEAIALQSRGWPRVINTLATTCLLYGYQLKKDAIDEEVVRMAAEEMGY
>NZ_CP016552.1|WP_015375155.1|1947627_1948263_-|3-hexulose-6-phosphate-synthase
MELQLALDLVNIPEAKQLVKEVEEYVDIVEIGTPVIINEGLRAVKEIKQEFPHLKVLADLKIMDAAAYEVMKASEAGADIITILGVAEDLSIKGAVEEAKKQGKKILVDMIGVKNLEERAKEVDGFGVDYICVHTGYDLQAVGKNSLEDLATIKRVVKNAKTAIAGGIKLNTLPEVIKAKPDLIIVGGGITGQEDKRAVAAEMKKMIQQGE
>NZ_CP016552.1|WP_095860231.1|1947066_1947624_-|6-phospho-3-hexuloisomerase
MQATQYLGEIIKELNQTADLIAAGEAEKLVNEILKAKKIFVAGAGRSGFMSKSFAMRMMHMGLDAYVVGETITPNLEQDDILIIGSGSGETRSLVSMAEKAKSLGATVALVTIFPESTIGQLADITVKLPGSPKDQSDNGYKTIQPMGSLFEQTLLLFYDAIILRCMEKKGLDSNTMFKRHANLE
>NZ_CP016552.1|WP_081106643.1|1946327_1946663_+|bis-aminopropyl-spermidine-synthase-family-protein
MLERGMGLERVAEQRCEVCAGRGIVLRPPFDSVLAAFQDIAAMRPKATPDFDQGYVTPETTVRRLALMAQQGDLMGRDCPPSAAGIPVAEGGRFVRRFLTSACGVAFFKVC
>NZ_CP016552.1|WP_033015477.1|1945552_1946224_+|hypothetical-protein
MEYRRITSIEDPLFKKMHQLMQNVFPPEEVLAFDLWKEPLEDPGIRVCVAVHEGEVVGATEYRYYEDLNVAMTDFTIIGQAGLGIGRFLAKKRLEDLQNWAAANGKQLYGMFAEIYDPYRVKHYEFGGIKPMDPYVRREVLSHLGYKRLDFPYVHPSWNNDGEAVTGLDLCFLPMDDSVNELPADLVVKFLKRYYSVLSNKPRDWYEMMEKLEAKNTIPLLPI
>NZ_CP016552.1|WP_013144995.1|1957205_1957469_-|CRISPR-associated-endonuclease-Cas2
MFVIITYDVAEKRVNKVCKKLKEYLTWTQNSVFEGEISKSLLMKCMYELEMIIDKEEDSIYLYEVGNPKNIKKRVFGQEKNFDELFL
>NZ_CP016552.1|WP_044746556.1|1957472_1958456_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MLKDHYIFSNGRLKRKDNTIYFLDEKENKRSLPVHQIENLYIFGEVDFNSALLNLLSQHEVHLHIFNYYGFYAGTFCPRNRKVSGFTVVQQSAHYLDNGKRLYIAKMFLESAVHHMLRNIRRHREKTEIYIHQIEEETKKLDAASTIQELMGIEGRIRQHYYQSFNGILKQDFTFEKRTKQPPRDPLNALISFGNSLCYTTVLGEIYKTPLDPTVSFLHEPSTRRFSLSLDLAEIFKPLIVDPVIIASINNRIITNKHFDDIDGMVFLNEEGKKKFIMEWENKLATSIQHRKLKRKVSYRHFIRLECYKLIKHFIGDERYKPLKAWW
>NZ_CP016552.1|WP_013144993.1|1958455_1958953_-|CRISPR-associated-protein-Cas4
MASGVQIHYYKVCKRKLWLFSKGIGMEEEHERVIEGKILHERAYPRLNEREILIDDTFKLDALEEEYVREIKISSKMAEADRFQMLYYLYELKKRGIHKKGLISYTKERKTEEVILTEEDERKVEKALKDIYQILQLPSPPPLKKLSYCSKCAYYEFCYALEGDE
>NZ_CP016552.1|WP_095859520.1|1958967_1961145_-|CRISPR-associated-helicase/endonuclease-Cas3
MFYAKSETKETIREHTDRLLDNWRLLKDSYGDRLIRVNERMWELLRLAIEYHDIGKANTVFQNKIRRAIQEELLETDCDANVPHNYLSVGLVPFEQLNLTKEEIRLLTHAIGYHHERDKRPDKEAIRDILENDLQKQREAIAHHMRLPLAEKVSFRFVDRLLKRYTIHEGGSFWDYVLLKGLLQRIDHAASAHLPVESDVHQDVGVYVRRYMENKSFHLNDLQRFTAGHTHKNVIVIAQTGMGKTESALLWIDRDKAFFTLPLRVSINAIYERVRHQMGYDAAGLLHSTSAFYLVERGEENWEAIKQQSQQLSMKLLFTTVDQILKFPFYYRGFEKELASMANAKVVIDEIQAYDPKIAAMLIKSLEMIKKVGGRFMIMTATLPTLYLDELKRRSIIDEEDTVFGEFIDSQNHRHRIQLHDEEITEGIEDFVKMARSSQVLVIVNTVRRAMELYERLSEMGSDVPVHLLHSQFTQEDRQWLERQIQEFNEAKTNGVWITTQLVEASIDIDFDYLFTEMSPLDSLFQRLGRCYRRRVIEGEQCNIHIFTQNVSGVPSVYDGHLVCESTELLRPFDRQILDERTKIELVGKLYERERLKGTSFLQEFEDALAMFDHLDPYEMSKKEAQRKLRDIQTVPIIPRRIYDEIADVIDECRRCRNWQERIRLRMEIEKKTISVHRFLAEKCVSERLPKPFDHIYIADVEYDFDREVGRGRGIQFDTPLSAFY
>NZ_CP016552.1|WP_061580951.1|1961168_1961870_-|type-I-B-CRISPR-associated-protein-Cas5
MKALRLKLFQETACYKKPFASKVAETYPLPPYSTVKGMIHALLRADRFIPMRLSVQGEYEAKLLDYQRHYFFKKRNVAAFPLILDGIQDELFSYDAKEITTMPIYTHLLYRVDLLIHVEAEKEVLERIIHAIETGENHYSLGRWEDLVRIDEYKIVQVDELDEEKDLRYYAYIPHHLLDIDIKHIPYELPWKYEVVNGVRKWEKINVGYVRKGTTAPEGVCVDEDGELVFFHL
>NZ_CP016552.1|WP_095859521.1|1961872_1962760_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MTKTVTMTIVFQAGSLNYGEGIANISELKKFHRGNGEAYTYASRQSLRYDIVRLGNELFGWNLNTVDKASGVVQFKKDVTIEDSVEMDLFGYLKTDKNSQKRAAVVRLSHAISLEPYKSDLEFLNNMGLASRIGADPNLAQIEQHQSFYCYTITIDLHRIGVDGEVELSNQEKAKRVQQLLDIVKLLNRNIRGRRENLSPLFVIGGVYDVANPFFLGKIRLSSSPRGWEIDLAPIEDTMAQTFAGKAVADETRIGLVSGIFANEDEFAQRFAEKTGSVEQFFRHIAEQVQTYYGE
>NZ_CP016552.1|WP_095859522.1|1962756_1964553_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MRIELRMGEWMVTMGLVGLYRVFEYGLENRLIDQQYKNSIRIVPQGLELETGVLPLLPRAYFHYLLDEYSTAKRTRERLLSYLGQAKKENLFSTALANIKKTITDTGKKIQQYFPDEPISPLLEALKSIKKPEQIEQLEQCIAEFQQLLSKEAINEKLTLNYFKAAVLKSFFGQVSFLNVSKNHLDLEGHIEQFQADYIVPVQRDLQLEQILRSASAEKDVLRFLDEHVEYEPFKALKRAWKKKPLPQMQEELKSVYECMLFPGRIAFYNFEEMIFSPIGITSKAFNFNWDLQDKQPKPISSLAKLVLFFAPAGAAIYLKKEGFQDQNEYRMYAGFVQSDAPFPEILQKNNHLKQMKQQKDPFDRIVSKLVQSVTKEASYVVDHLFFLEFSSDYDSKKTHLHYYHLPLYLARYFVEYPGKLDYVHYDYREQFIQDVLRGADPARVIYQYLRDCIENGRSHIGPYIAVRERSRIMQLKRGGKEMEKTDKRVYALYRCGQEIRKALEQAGSPKTADRYSASPSKKISAIAYRLLNAAKAGDRKSFLDTLFRLHMSADQPISPLFLNALHERDLDFPAVANAFIAGLLSQEGQGEQEEVVS
>NZ_CP016552.1|WP_095859523.1|1964549_1965275_-|CRISPR-associated-endoribonuclease-Cas6
MRLTCSFKVERMPVSYRMMLVSMIKEALRVSDEQYYERLYDSVSMKPFSFSTYLKNFRFADQEVYLEGITITVSSPDHEFLLHLYNGLQQKQVFLYKHYQLVKEKIRMLPEKTITDSTAVFRTLSPMLVEDKNQKPVSPDAPDYEEHVNYLADLILRQYRGNGLLSPLIVRPLRWRKVVVKETNHEFEATHGGGDVLYFTAYQTLFSLTGHPTDLQLLYQLGLSKRRNQGFGLLEVEEVRG
>NZ_CP016552.1|WP_095859524.1|1965591_1968048_-|DEAD/DEAH-box-helicase-family-protein
MSKVKLISRRLLDKLQEQMSRSSTIYILTSFAMKSGVHLLKGSLRAAAERGADIKICVGDYLFVTQPEALRELISIHPDIEVRLYRSEGISFHPKAYLFEDTEGGYFIVGSSNLSRSALTDGVEWNLGLDKSVDEDVFAEAMEQFLKLFYAPETVPVNTETVDDYEKQHQDYHQRHPNLARIWAETEEIELMLPTETEKKQEEETADKIDVVHETAAPYGTIQPRFAQVEALERLEAAYEEGYDKAMVVMATGLGKTYLAAFFAHRFSRVLFIAHREEILRQAKRSFERVIPDRTAGLYDGNQKDRDADMVFASIFTLSMKKHLHSFRSDAFDLIVVDEFHHAAARSYDRVLRYFQPKFLLGITATPDRSDNKDVYALCDGNVAYRIDFIEAVQRGWLAPFHYYGVYDDTDYSQIKWLGNRYDEEELLQAQLREEMAEKILRAWEKYKKTRTLVFCSSIRQADFLSEYFQRRGYRTVSLHSKQTAISRQQAIAMLERRELDAIFTVDLFNEGVDIPSVDTLLFVRPTESLTVFTQQVGRGLRLYKGKDYCVIIDLIGNYRNADVKLRLFDTQRGETKKKAREPVMPTVPETCELHLDVQAIHLLEEMQKKRQPRKERLLADYRELKQELGRRPTYLELHLQGRSEAAEYKQEFGSYVGFLYWAGELSELEKEVFRKYEPWLVEVERTVMSKSYKMVVLKAMLERGSSGWHEPITPQQAAAFFHRYLTEKEYRKRIDFSDGETKRLWQYDEEKVSKLIARMPMTKWSGSSRGLISFENNVFALQFSIAREHEEILYNWTKEICEYRLHVYFEKKEGLMN
>NZ_CP016552.1|WP_033015496.1|1968040_1968367_-|nucleoside-triphosphate-pyrophosphohydrolase
MPIYNKLVRDCIPTIIEQAGKTFTTRILDDEEYRKELQKKAFEELEEYVQAETDEAALEELADVLEIIHALAECHGASIEQVEQIRAKKAEKRGGFREKIFLIEVHDE

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Crispr_ID: NZ_CP016552_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP016552_9

3389117-3389214

Orphan

Consensus_repeat	Method
TTGCTCATGGAACTTTTCCGTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP016552_9

>merge|NZ_CP016552|9|3389117-3389214|CRISPRCasFinder
TTGCTCATGGAACTTTTCCGTGAAAATCCCGTCAGCCAGCGGTGATTTTCATCCCCGGGTGGAGGGCAGATCGTGTTGCCCATGGAACTTTTCCGTGA

>NZ_CP016552|9|9|3389117-3389214|CRISPRCasFinder
TTGCTCATGGAACTTTTCCGTGA	AAATCCCGTCAGCCAGCGGTGATTTTCATCCCCGGGTGGAGGGCAGATCGTG
TTGCCCATGGAACTTTTCCGTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP016552.1\|WP_095860143.1\|3387722_3388859_-\|IS110-like-element-ISGka2-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP016552.1\|WP_095860147.1\|3396383_3396758_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181281
NZ_CP016552.1\|WP_021321312.1\|3393145_3394039_+\|phosphate-ABC-transporter-permease-PstA	unknown	unknown	gnl\|CDD\|223654
NZ_CP016552.1\|WP_095860142.1\|3384462_3385599_-\|IS110-like-element-ISGka2-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP016552.1\|WP_094239823.1\|3376208_3377327_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226957
NZ_CP016552.1\|WP_062679206.1\|3378641_3379331_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP016552.1\|WP_095859838.1\|3394360_3395548_-\|IS701-family-transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP016552.1\|WP_011232902.1\|3391279_3392140_+\|phosphate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270371
NZ_CP016552.1\|WP_095860148.1\|3396848_3398084_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP016552.1\|WP_110107477.1\|3395677_3395845_-\|HTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|226234
NZ_CP016552.1\|WP_095860145.1\|3392213_3393149_+\|phosphate-ABC-transporter-permease-subunit-PstC	unknown	unknown	gnl\|CDD\|273992
NZ_CP016552.1\|WP_095858915.1\|3386016_3387153_-\|IS110-like-element-ISGka2-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP016552.1\|WP_011232912.1\|3398201_3399335_+\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP016552.1\|WP_020279908.1\|3373755_3374556_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|225806
NZ_CP016552.1\|WP_094239822.1\|3377340_3378639_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NZ_CP016552.1\|WP_095860146.1\|3395863_3396358_-\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376324
NZ_CP016552.1\|WP_094239821.1\|3379327_3379738_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP016552.1\|WP_095858915.1\|3382908_3384045_-\|IS110-like-element-ISGka2-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP016552.1\|WP_033011561.1\|3372512_3373763_+\|IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP016552.1\|WP_095860144.1\|3389505_3391263_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377924

Protein	Function_ID	Function_description	E-value
NZ_CP016552.1\|WP_095860143.1\|3387722_3388859_-\|IS110-like-element-ISGka2-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	6.54361e-30
NZ_CP016552.1\|WP_095860147.1\|3396383_3396758_-\|hypothetical-protein	gnl\|CDD\|181281	PRK08194, PRK08194, tartrate dehydrogenase; Provisional.	8.0201e-50
NZ_CP016552.1\|WP_021321312.1\|3393145_3394039_+\|phosphate-ABC-transporter-permease-PstA	gnl\|CDD\|223654	COG0581, PstA, ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism].	5.05753e-77
NZ_CP016552.1\|WP_095860142.1\|3384462_3385599_-\|IS110-like-element-ISGka2-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	5.74432e-30
NZ_CP016552.1\|WP_094239823.1\|3376208_3377327_+\|ABC-transporter-permease	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	7.62223e-13
NZ_CP016552.1\|WP_062679206.1\|3378641_3379331_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	5.61693e-109
NZ_CP016552.1\|WP_095859838.1\|3394360_3395548_-\|IS701-family-transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.52543e-11
NZ_CP016552.1\|WP_011232902.1\|3391279_3392140_+\|phosphate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.7611e-88
NZ_CP016552.1\|WP_095860148.1\|3396848_3398084_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	6.01214e-40
NZ_CP016552.1\|WP_110107477.1\|3395677_3395845_-\|HTH-domain-containing-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	0.000237968
NZ_CP016552.1\|WP_095860145.1\|3392213_3393149_+\|phosphate-ABC-transporter-permease-subunit-PstC	gnl\|CDD\|273992	TIGR02138, phosphate_transport_system_permease_protein_PstC, phosphate ABC transporter, permease protein PstC. The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions].	1.57815e-78
NZ_CP016552.1\|WP_095858915.1\|3386016_3387153_-\|IS110-like-element-ISGka2-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.66327e-30
NZ_CP016552.1\|WP_011232912.1\|3398201_3399335_+\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP016552.1\|WP_020279908.1\|3373755_3374556_+\|AAA-family-ATPase	gnl\|CDD\|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	1.09551e-38
NZ_CP016552.1\|WP_094239822.1\|3377340_3378639_+\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	4.69515e-10
NZ_CP016552.1\|WP_095860146.1\|3395863_3396358_-\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|376324	pfam00358, PTS_EIIA_1, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1.	1.33778e-69
NZ_CP016552.1\|WP_095858915.1\|3382908_3384045_-\|IS110-like-element-ISGka2-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.66327e-30
NZ_CP016552.1\|WP_033011561.1\|3372512_3373763_+\|IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.92786e-20
NZ_CP016552.1\|WP_095860144.1\|3389505_3391263_+\|hypothetical-protein	gnl\|CDD\|377924	pfam07833, Cu_amine_oxidN1, Copper amine oxidase N-terminal domain. Copper amine oxidases catalyze the oxidative deamination of primary amines to the corresponding aldehydes, while reducing molecular oxygen to hydrogen peroxide. These enzymes are dimers of identical subunits, each comprising four domains. The N-terminal domain, which is absent in some amine oxidases, consists of a five-stranded antiparallel beta sheet twisted around an alpha helix. The D1 domains from the two subunits comprise the 'stalk' of the mushroom-shaped dimer, and interact with each other but do not pack tightly against each other.	7.63056e-14

>NZ_CP016552.1|WP_095860143.1|3387722_3388859_-|IS110-like-element-ISGka2-family-transposase
MDVIYPRCAGLDVHAETIVACALWEEDGHIQKDIQTFSTFSKGLGDLLEWLEEHGVTHVAMESTGVYWKPVFAFLEGYVDLTLANPQRIKNVPGRKTDVSDAEWIAKLLRHGLIEKSFVPPADIRELRDFTRLRKKWVGQLTSEKNRIQKVLESSNVKLGSVLSDLFGVSGKDILARLLEKGYVDKDELDQCLRGRLKKKKQAVYDSLLGTLTEHELRLLRLLWKHVEELEQLIEEVDQHIDRLLEPYREEVNLLMTMPGVKKQTAAVIIAEMGTDMSVFETPERAASWTGLSPGNHESAGKRKSTRTTKGNPHLRSALCEAAWSAARSKTHPLSRKFWSLAARCGKKKALIAIARRMLVIIFCMISRKEPFRQPQLI
>NZ_CP016552.1|WP_095858915.1|3386016_3387153_-|IS110-like-element-ISGka2-family-transposase
MDVIYPRCAGLDVHAETIVACALWEEDGHIQKDIQTFSTFSKGLGDLLEWLEEHGVTHVAMESTGVYWKPVFAFLEGYVDLTLANPQRIKNVPGRKTDVSDAEWIAKLLRHGLIEKSFVPPADIRELRDFTRLRKKWVGQLTSEKNRIQKVLESSNVKLGSVLSDLFGVSGKDILARLLEKGYVDKDELDQCLRGRLKKKKQAVYDSLLGTLTEHELRLLRLLWKHVEELEQLIEEVDQHIDRLLEPYREEVELLMTMPGVKKQTAAVIIAEMGTDMSVFETPERAASWTGLSPGNHESAGKRKSTRTTKGNPHLRSALCEAAWSAARSKTHPLSRKFWSLAARCGKKKALIAIARRMLVIIFCMISRKEPFRQPQLI
>NZ_CP016552.1|WP_095860142.1|3384462_3385599_-|IS110-like-element-ISGka2-family-transposase
MDVIYPRCAGLDVHAETIVACALWEEDGHIQKDIQTFSTFSKGLGDLLEWLEEHGVTHVAMESTGVYWKPVFAFLEGYVDLTLANPQRIKNVPGRKTDVSDAEWIAKLLRHGLVEKSFVPPADIRELRDFTRLRKKWVGQLTSEKNRIQKVLESSNVKLGSVLSDLFGVSGKDILARLLEKGYVDKDELDECLRGRLKKKKQAVYDSLLGTLTEHELRLLRLLWKHVEELEQLIEEVDQHIDRLLEPYREEVNLLMTMPGVKKQTAAVIIAEMGTDMSVFETPERAASWTGLSPGNHESAGKRKSTRTTKGNPHLRSALCEAAWSAARSKTHPLSRKFWSLAARCGKKKALIAIARRMLVIIFCMISRKEPFRQPQLI
>NZ_CP016552.1|WP_095858915.1|3382908_3384045_-|IS110-like-element-ISGka2-family-transposase
MDVIYPRCAGLDVHAETIVACALWEEDGHIQKDIQTFSTFSKGLGDLLEWLEEHGVTHVAMESTGVYWKPVFAFLEGYVDLTLANPQRIKNVPGRKTDVSDAEWIAKLLRHGLIEKSFVPPADIRELRDFTRLRKKWVGQLTSEKNRIQKVLESSNVKLGSVLSDLFGVSGKDILARLLEKGYVDKDELDQCLRGRLKKKKQAVYDSLLGTLTEHELRLLRLLWKHVEELEQLIEEVDQHIDRLLEPYREEVELLMTMPGVKKQTAAVIIAEMGTDMSVFETPERAASWTGLSPGNHESAGKRKSTRTTKGNPHLRSALCEAAWSAARSKTHPLSRKFWSLAARCGKKKALIAIARRMLVIIFCMISRKEPFRQPQLI
>NZ_CP016552.1|WP_094239821.1|3379327_3379738_+|hypothetical-protein
MNKKGIWSVIAVIMTAIILSGWYYAFYNKQNFESSAEGTFLPEEYEPQYHVFEATINVDENKFDQLLIEHRIDLREGSLKYALYNPNGKLVEKGEVKAGTPFAKTLKVKPIKGEWMAKYYINKETDGHYLLRMKSS
>NZ_CP016552.1|WP_062679206.1|3378641_3379331_+|ABC-transporter-ATP-binding-protein
MALIELEKISKKYGKDEYTTVALKGIDLKVHNGEFVSIMGPSGSGKSTLLNIIGCMDVPTEGIYRLNGINVTTLRDKELSQIRNRTISFVFQHFALMHNFTVFENVALPLFKRDISKKEIKEKVDYYLEKLGIADLRKKNVSKLSGGQKQRVAIARAMAAETDIVLADEPTGALDQENGARLMELLCQMNEEGKCIIVITHDEKVASYTKRIVRIVDGQIQSDTKGERQ
>NZ_CP016552.1|WP_094239822.1|3377340_3378639_+|ABC-transporter-permease
MKYTRIAFASIVKRKLSILLMALQLVVSFWMINHALITIDTLNYQEKQLFSISKMDEYKTVKLTMPDGDDTQWFAERFRQLETYIKSLPEIKGYGSFNTTSIVPQDFPKWQKYQQRNKQLYAGTRREDDIESSGIIYFDYDIYRLFTKFVVIKGRMLEEADFQKENNDVIPVLVGYDYRDVFRIGDRFKAEAGAGEKTIKVTYEVVGILEKGSRWLSGNDYFVSPADNLDHFFVAPFFPEQREGRPISVAVRLHNTFIQLHSEKQFKDVKAAIMKKGKELGISPVLQTVRKDVDAYQENTRKSNHYALAIGTFFLVVTLIGVISVTISSIRARKYEFGVMMVTGASKRDISFMLIMELFFLIGISAVIGVIVSYLTEVNNDFLGYNIRLEAFTWWLYGKVAIIAIFIILFSAIIPLWNIKKLELRELVEGRE
>NZ_CP016552.1|WP_094239823.1|3376208_3377327_+|ABC-transporter-permease
MIFYSIKNQLKAHPITTFFIVLGLSLSVLMISVGISSINYSQLLEQEQARYQPRHAVSVDITFAKEPNWQHILELFESIDPQTGVILEDVTLPHRDAMMAVTPEYWTKEVVERFPLMQGRYFTIKEVRRGEKVALVGKERMEDVIIEGSEQYLMAGRDKYKVIGIIGVKGKKTRAIDYQVVIPMTSLPADTINKLTSTKQLHLTIHNPVKDTYPDEKIIRNNMEQLFPEAQMDVSPYMSNTMFHVELSERLSLMVMIYLLAIVNAINLTSYWIQERTYEIGIKKAFGYSNYDIVSMLFWEMCLISSTSVIIGYTIQLAFNRVIEQWIDYPINISITHLSTAVLFVVLSAALTIIIPAIKAIKIQPVDVMNRR
>NZ_CP016552.1|WP_020279908.1|3373755_3374556_+|AAA-family-ATPase
MYKTFYSLSREPFAKETDPSEAYQGAAFQEALRALEYVKRTRGIGLLIGEPGAGKTFALRAWKESLSPSLYHVVYFPLSTGGVMDFYRGLALGLGEEPKYRKVDLFRQIQQAIERLHHERRITPVFILDEMHLAKDAFLQDIAILFNFEMDSTNPFVLMLAGLPHLQGKLRLNQHRPLDQRIIMRCRMGPLEKEEVAGYIEHRMKQAGAKHPIFTPSALEAIALQSRGWPRVINTLATTCLLYGHQLKKDVIDEDVVRMAAEEMGY
>NZ_CP016552.1|WP_033011561.1|3372512_3373763_+|IS481-family-transposase
MDESMRHDIALFRYGLIAPLVNGQVEPKAYLNEVGGRVHSIPHQGDKPIAAKTILDWCARYKKGGFDALKPKRRSDRGRSRRLSPDDEDHILALRKEHPSMPVTLFYEQLTKQGDIPTTLSYFTIYRLLKKHNLVGKEILPMPERKRFAYDQINELWQGDLSHGPTIRVHGKAQKTFLIAYIDDCSRLVPYAQFFPSEKFDGLRIVTKEAVLRCGKPKRIYSDNGKIYRSEVLQYACAEMGITLIHTQPYDPQSKGKIERFFRTVQTRFYPLLELDPPKSLEELNERFWRWLEEEYHRKPHASLDGKTPHEVFQSQVHLVSFIEDSDWLDAIFLKREHRKVKADGTITLNKQLYEVPPRFIGQSIELRYDERGVYVYEEGKRVAEAIRVRMEDNAYVKRHRSPFAAVSAKEGEQDV
>NZ_CP016552.1|WP_095860144.1|3389505_3391263_+|hypothetical-protein
MKKIIAGTVMATALLAASTSSWTTLDGHAYAAVEKNTSASRYIVNVNGKLMTVRSLHRSGTVLLAGSDMAKLFSADYRYDQKHQYYEIRRTSPNVRIVLQIGKKAALVNGKSVSLSVAPQRFGQELYVDAKQIAALLGGQWKAEAGVSIVSTSGSLRPFRETWQVNGSTATIHGLVLGQTSFYSVNDVAAAFGATVHVDKKTSMVKVKKGNRTILFHPFSYVLNAGGKKTSLPTAPFIQNGVPYINLSAIVYALGGDIEEEDRFIATSGFIKGTSINPQWIDQNTLLISRPDEASSLLLDIRSRTAIRSINEMDLTLSHDGKKAAYVDENGHLFVIDFVSNTVQQIGEDDEVKTDLVWSSDGRSLYCIYGSNNEAVAVVALDNGTVTKLIDDKVKYKTDLRLSSDGTKLLYTVANEGKTNYTDDQKTDVDSINTSGTDPQLILVDLSSPTKQPTPLTSSPDNKVDSAFLSNHDIVYVSATDDEMSPPSLKVIRNGVEQTLLDKQNIIDMAVVKSRIYVVVEANDLYTIRCFDPSTKSWTTMGSTKNEITSIAPSPYDDQIAVTMATDGGENVSLLRHGSWMNLTK
>NZ_CP016552.1|WP_011232902.1|3391279_3392140_+|phosphate-ABC-transporter-substrate-binding-protein
MKRSTLWKRVISAVLSSTLLLGAALATEHRADAAEVSGKIVIAGSTALLPLTQQAAKEFKKSHPKVKIVVSGSSSIAGPQSVTKGVATIGACDWDATKAVGGFPAYKGLKAYKIAKIPFAVIVNKGNPVSNLSVEQIQDIYEGKIKNWKQLGGKDEEIVVINRAKGSGTRVNFEDKIMDGHMIKTTGDNYKEVQKSGDMVNAVASNPNAIGFVDLAYVKGGIKAVSINGVKATTANAKSGKYIFYGYGYLLTKGEAKGADKAFIDYILSKKFQNGSLKKLKFIPVK
>NZ_CP016552.1|WP_095860145.1|3392213_3393149_+|phosphate-ABC-transporter-permease-subunit-PstC
MEKLSPDWTEATRLLTAQRQRWTTKYRFDRLFRFFCLTSIVFLIVVLSAIVLFVSKTGLLVFRDVSPWEFFFSSRWDPEHHRYGAAVFITGTLYVTFVTLLIATPISISTAVFIAEMAPPRLQQWLRTLLDLLVGIPSIVYGYLGATLLVPWIRKLTGAPVGDGILAAAIVLSMMILPTITRITDDALCAVPNEWREANYALGGTKIEMISKILLPAAKSGIAAAVILGMARAIGETMAVVMVIGNVAQWGFDLVTPSSVLTSHIVMQILNVDFQSTTNHALYMMALLLLFISISLIMIIRRLRLKGGPSS
>NZ_CP016552.1|WP_021321312.1|3393145_3394039_+|phosphate-ABC-transporter-permease-PstA
MNNQALGLHGKMSRLRIRRLMNRLVLGMISIISATVFFIILSLLYIIVRKGLSDIDIHFLIGLPEEIDAGGGVGPFLWNSIYILVLSLLLSLPIGIGAGIFLAEYAPNNRIMEWVRAAIESLASVPSIVFGLFGYALFVEYFQIGVTILGASITLALLNLPVLARVSEEAITAVPSAWREASFALGATKAQTIVKTVLPAAMKGILTGISLVACRAFGESAIILLVGGTSSSGEMWDFHLLSEGATLPVHLWYIQSEALVADAQQIAQKTSALLVLLVLFLSFIIRFPLWLSQRKKR
>NZ_CP016552.1|WP_095859838.1|3394360_3395548_-|IS701-family-transposase
MNRLAHHQGIHKFFFTLGLTLQLSKPVIKHLIHIVDALTTKGFSGTLTDIHYWSFHPNHRTTLSHFFTKSPWNEERLLGKLQEWILSQVERLAKRKNQPLFVSIDDTICQKTKPSSRAAHAIQGCDWHYSHKDHQSVWGHSLVWLMVHTFTQAFPFAFRLYDKKAGKSKIDLAIEMLSSLKVKRAQPVYVLMDSWYPSKKLIEACLKQGFHVIAMLKTNRILYPKGIAIQAKQFARYIESKDTRLVTVGQERYRVYRYEGAIHGLDDAVVLLAWKADQPMTPEHLHCVLSTDRELGDEDILRYYAQRWTIECFFRQAKDQLKLDGYRVRHIRAVKRYWAVVLLACVYSIAESRQNLSTGLELLRSRKDHSVVEFIYDAAKQDIPIDVIKKQLRIA
>NZ_CP016552.1|WP_110107477.1|3395677_3395845_-|HTH-domain-containing-protein
MFTKRQKEILSFLAHSKDLIPDEWMAKQLGISDRTVRHDGGEKNLSVKKYGCFKS
>NZ_CP016552.1|WP_095860146.1|3395863_3396358_-|PTS-glucose-transporter-subunit-IIA
MFKKWFGKQQPKEETITAPLDGTIVPLEDVPDPVFAQNMMGDGIAIDPADGDVVAPVDGEIFQLFPTKHAIGLRSVAGVELLIHVGIDTVSMNGEGFTAYVRAGDRVKRGDRLLSVDLPLVREKAKSAVTPIIITNGDALESLEREAEASAKKGETVLFHVNMK
>NZ_CP016552.1|WP_095860147.1|3396383_3396758_-|hypothetical-protein
MAALSVQGRKEGILPRMKKWDIAVIPSDGIGKKAVLVANMHVNGKYPSMFEPVHGSAPDIYGKGIANPIGQIWTAKLMLDHFGEEELGALLLQTIEDVTADGIKTPDLGGTACGFLPFRYTVFR
>NZ_CP016552.1|WP_095860148.1|3396848_3398084_+|PucR-family-transcriptional-regulator
MSYDTDPFRGESDSLEEFADRVSDVLKCPVTIEDANHRLIAYSAHDDYTDPARTATIISRRVPEKVINSLWKQGAIPALLKSREPVRVPPIHDVGLGSRVAVSIWKNDEVIGFIWVLETNRTLSPEEMEWLKLAAKAAKNKVLQLYMRKNKKEERVQELFWKLLTSHIAAEDEIRAHLAAMQIPTAPQFAVVVFRFAADLTAEMERQISYLLQTTQQIPILLYTTDGRDVILLGAPKTDQPLKELSAFIESFAAKMKERFHIHDVQCGFGGVYGAYRLIEKSYREALAVLALKEKLGDEIKSVYGYAQLGIYQFFDFLLEQKRQGEWTNPALTKLQSYDQKHHSDLVKTFETFFDHNENAQETADVLNVHPNTLAYRLKRIADIAELDLNDMNQKIKLYIDIKLAKYEARG
>NZ_CP016552.1|WP_011232912.1|3398201_3399335_+|alanine-dehydrogenase
MIIGVPKEIKNNENRVAITPAGVLSFVQAGHTVLIEKEAGVGSGFNDSDYARAGAQIIERAEDVWAQADMVMKVKEPLPSEYRFFRPGLVLFTYLHLAADPELTRVLKESGVIAIAYETVQVGRTLPLLTPMSEVAGRMAAQIGAQFLEKPYGGKGILLGGVPGVARGKVVIIGGGVVGTNAAKVAVGLGADVTIIDLNADRLRELDDIFGNQITTLMSNPMNIAEAVAEADLVIGAVLIPGARAPKLVTEDMVKAMKPGSVIVDVAIDQGGIVETSDHVTTHDNPTYVKHGVVHYAVANMPGAVPRTSTIALTNVTIPYALQIANKGVMQAITDNPALELGVNVANGEITYEAVARDLGYRYVPAREALGKTLAAN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NZ_CP016552_9	9.1\|3389140\|52\|NZ_CP016552\|CRISPRCasFinder	3389140-3389191	52	NZ_CP016552.1	1739004-1739055	1.0
NZ_CP016552_9	9.1\|3389140\|52\|NZ_CP016552\|CRISPRCasFinder	3389140-3389191	52	NZ_CP016552.1	2006870-2006921	1.0
NZ_CP016552_9	9.1\|3389140\|52\|NZ_CP016552\|CRISPRCasFinder	3389140-3389191	52	NZ_CP016552.1	3042989-3043040	1.0
NZ_CP016552_9	9.1\|3389140\|52\|NZ_CP016552\|CRISPRCasFinder	3389140-3389191	52	NZ_CP016552.1	3382696-3382747	1.0
NZ_CP016552_9	9.1\|3389140\|52\|NZ_CP016552\|CRISPRCasFinder	3389140-3389191	52	NZ_CP016552.1	3387435-3387486	1.0
NZ_CP016552_9	9.1\|3389140\|52\|NZ_CP016552\|CRISPRCasFinder	3389140-3389191	52	NZ_CP016552.1	3387510-3387561	1.0

1. spacer 9.1|3389140|52|NZ_CP016552|CRISPRCasFinder matches to position: 1739004-1739055, mismatch: 0, identity: 1.0

aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	CRISPR spacer
aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	Protospacer
****************************************************

2. spacer 9.1|3389140|52|NZ_CP016552|CRISPRCasFinder matches to position: 2006870-2006921, mismatch: 0, identity: 1.0

aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	CRISPR spacer
aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	Protospacer
****************************************************

3. spacer 9.1|3389140|52|NZ_CP016552|CRISPRCasFinder matches to position: 3042989-3043040, mismatch: 0, identity: 1.0

aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	CRISPR spacer
aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	Protospacer
****************************************************

4. spacer 9.1|3389140|52|NZ_CP016552|CRISPRCasFinder matches to position: 3382696-3382747, mismatch: 0, identity: 1.0

aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	CRISPR spacer
aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	Protospacer
****************************************************

5. spacer 9.1|3389140|52|NZ_CP016552|CRISPRCasFinder matches to position: 3387435-3387486, mismatch: 0, identity: 1.0

aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	CRISPR spacer
aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	Protospacer
****************************************************

6. spacer 9.1|3389140|52|NZ_CP016552|CRISPRCasFinder matches to position: 3387510-3387561, mismatch: 0, identity: 1.0

aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	CRISPR spacer
aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	Protospacer
****************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	CP011833	Geobacillus sp. 12AMOR1 plasmid pGARCT, complete sequence	28758-28787	0	1.0
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	NZ_CP025075	[Bacillus] caldolyticus strain NEB414 plasmid pBcl1, complete sequence	25169-25198	0	1.0
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	NZ_CP014336	Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence	9136-9165	0	1.0
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	NZ_CP014336	Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence	41899-41928	0	1.0
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	CP008904	Geobacillus sp. LC300 plasmid pGt35, complete sequence	23254-23283	0	1.0
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	NC_006509	Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence	1020-1049	0	1.0
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	CP017693	Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence	25865-25894	0	1.0
NZ_CP016552_2	2.9\|349125\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349125-349153	29	NC_006509	Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence	15788-15816	0	1.0
NZ_CP016552_2	2.9\|349125\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349125-349153	29	NC_010420	Geobacillus stearothermophilus plasmid pGS18, strain 18	13142-13170	0	1.0
NZ_CP016552_2	2.11\|349255\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349255-349283	29	NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	14911-14939	0	1.0
NZ_CP016552_2	2.11\|349255\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349255-349283	29	NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	85021-85049	0	1.0
NZ_CP016552_2	2.14\|349451\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349451-349480	30	CP008904	Geobacillus sp. LC300 plasmid pGt35, complete sequence	4349-4378	0	1.0
NZ_CP016552_2	2.14\|349451\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349451-349480	30	CP008904	Geobacillus sp. LC300 plasmid pGt35, complete sequence	38312-38341	0	1.0
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	CP011833	Geobacillus sp. 12AMOR1 plasmid pGARCT, complete sequence	28758-28787	0	1.0
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	NZ_CP025075	[Bacillus] caldolyticus strain NEB414 plasmid pBcl1, complete sequence	25169-25198	0	1.0
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	NZ_CP014336	Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence	9136-9165	0	1.0
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	NZ_CP014336	Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence	41899-41928	0	1.0
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	CP008904	Geobacillus sp. LC300 plasmid pGt35, complete sequence	23254-23283	0	1.0
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	NC_006509	Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence	1020-1049	0	1.0
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	CP017693	Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence	25865-25894	0	1.0
NZ_CP016552_6	6.3\|1831851\|37\|NZ_CP016552\|CRISPRCasFinder,PILER-CR	1831851-1831887	37	AB823818	Phage phi OH2 DNA, complete genome	27456-27492	0	1.0
NZ_CP016552_6	6.7\|1831851\|38\|NZ_CP016552\|CRT	1831851-1831888	38	AB823818	Phage phi OH2 DNA, complete genome	27455-27492	0	1.0
NZ_CP016552_8	8.6\|1955831\|39\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1955831-1955869	39	NC_009552	Geobacillus virus E2, complete genome	5652-5690	0	1.0
NZ_CP016552_8	8.7\|1955899\|35\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1955899-1955933	35	NC_019544	Deep-sea thermophilic phage D6E, complete genome	46312-46346	0	1.0
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	NC_013412	Geobacillus sp. Y412MC61, complete sequence	31042-31071	1	0.967
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	NC_014916	Geobacillus sp. Y412MC52 plasmid pGYMC5201, complete sequence	604-633	1	0.967
NZ_CP016552_2	2.7\|348993\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348993-349022	30	NC_041918	Geobacillus phage TP-84, complete genome	13900-13929	1	0.967
NZ_CP016552_2	2.11\|349255\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349255-349283	29	NC_010420	Geobacillus stearothermophilus plasmid pGS18, strain 18	32972-33000	1	0.966
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	NC_013412	Geobacillus sp. Y412MC61, complete sequence	31042-31071	1	0.967
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	NC_014916	Geobacillus sp. Y412MC52 plasmid pGYMC5201, complete sequence	604-633	1	0.967
NZ_CP016552_2	2.23\|348998\|30\|NZ_CP016552\|PILER-CR	348998-349027	30	NC_041918	Geobacillus phage TP-84, complete genome	13900-13929	1	0.967
NZ_CP016552_7	7.6\|1840465\|35\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1840465-1840499	35	NC_009552	Geobacillus virus E2, complete genome	37416-37450	1	0.971
NZ_CP016552_8	8.1\|1955519\|21\|NZ_CP016552\|CRISPRCasFinder,CRT	1955519-1955539	21	NZ_CP049914	Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence	505253-505273	1	0.952
NZ_CP016552_2	2.11\|349255\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349255-349283	29	NC_009329	Geobacillus thermodenitrificans NG80-2 plasmid pLW1071, complete sequence	4974-5002	2	0.931
NZ_CP016552_2	2.15\|349517\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349517-349546	30	NC_012794	Geobacillus sp. WCH70 plasmid pWCH7001, complete sequence	228-257	2	0.933
NZ_CP016552_2	2.15\|349517\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349517-349546	30	NC_009329	Geobacillus thermodenitrificans NG80-2 plasmid pLW1071, complete sequence	37677-37706	2	0.933
NZ_CP016552_2	2.15\|349517\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349517-349546	30	NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	53573-53602	2	0.933
NZ_CP016552_2	2.15\|349517\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349517-349546	30	NZ_CP020031	Geobacillus thermodenitrificans strain T12 plasmid pGeo12a, complete sequence	47529-47558	2	0.933
NZ_CP016552_2	2.15\|349517\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349517-349546	30	NZ_CP020032	Geobacillus thermodenitrificans strain T12 plasmid pGeo12b, complete sequence	41472-41501	2	0.933
NZ_CP016552_2	2.15\|349517\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349517-349546	30	NZ_CP049704	Parageobacillus toebii NBRC 107807 strain DSM 14590 plasmid pDSM14590, complete sequence	36828-36857	2	0.933
NZ_CP016552_8	8.4\|1955699\|37\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1955699-1955735	37	NC_019544	Deep-sea thermophilic phage D6E, complete genome	48940-48976	2	0.946
NZ_CP016552_2	2.3\|348730\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	348730-348758	29	JX676771	Pseudomonas phage AF, complete genome	41269-41297	6	0.793
NZ_CP016552_2	2.6\|348927\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348927-348956	30	KC699836	Bacillus phage SIOphi, partial genome	112365-112394	6	0.8
NZ_CP016552_2	2.6\|348927\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348927-348956	30	NZ_CP043834	Bacillus sp. BS98 plasmid unnamed4	33194-33223	6	0.8
NZ_CP016552_2	2.6\|348927\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348927-348956	30	NZ_CP020436	Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence	44758-44787	6	0.8
NZ_CP016552_2	2.16\|349583\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349583-349612	30	MT457553	Shewanella phage Thanatos-2, complete genome	112937-112966	6	0.8
NZ_CP016552_2	2.19\|348731\|29\|NZ_CP016552\|PILER-CR	348731-348759	29	JX676771	Pseudomonas phage AF, complete genome	41269-41297	6	0.793
NZ_CP016552_2	2.22\|348931\|30\|NZ_CP016552\|PILER-CR	348931-348960	30	KC699836	Bacillus phage SIOphi, partial genome	112365-112394	6	0.8
NZ_CP016552_2	2.22\|348931\|30\|NZ_CP016552\|PILER-CR	348931-348960	30	NZ_CP043834	Bacillus sp. BS98 plasmid unnamed4	33194-33223	6	0.8
NZ_CP016552_2	2.22\|348931\|30\|NZ_CP016552\|PILER-CR	348931-348960	30	NZ_CP020436	Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence	44758-44787	6	0.8
NZ_CP016552_2	2.1\|348597\|31\|NZ_CP016552\|CRT	348597-348627	31	NC_047750	Mannheimia phage vB_MhM_1127AP1, complete genome	17181-17211	7	0.774
NZ_CP016552_2	2.1\|348597\|31\|NZ_CP016552\|CRT	348597-348627	31	NC_028898	Mannheimia phage vB_MhM_587AP1, complete genome	17190-17220	7	0.774
NZ_CP016552_2	2.3\|348730\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	348730-348758	29	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	262567-262595	7	0.759
NZ_CP016552_2	2.9\|349125\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349125-349153	29	CP011076	Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence	15849-15877	7	0.759
NZ_CP016552_2	2.10\|349190\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	349190-349218	29	NZ_CP013632	Rhizobium sp. N324 plasmid pRspN324b, complete sequence	113330-113358	7	0.759
NZ_CP016552_2	2.14\|349451\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349451-349480	30	NZ_CP031942	Nostoc sphaeroides strain Kutzing En plasmid p1, complete sequence	21226-21255	7	0.767
NZ_CP016552_2	2.14\|349451\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349451-349480	30	NZ_CP031942	Nostoc sphaeroides strain Kutzing En plasmid p1, complete sequence	29823-29852	7	0.767
NZ_CP016552_2	2.17\|349649\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349649-349678	30	MN694433	Marine virus AFVG_250M1159, complete genome	25047-25076	7	0.767
NZ_CP016552_2	2.17\|349649\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349649-349678	30	NC_029106	Achromobacter phage phiAxp-2, complete genome	28982-29011	7	0.767
NZ_CP016552_2	2.19\|348731\|29\|NZ_CP016552\|PILER-CR	348731-348759	29	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	262567-262595	7	0.759
NZ_CP016552_2	2.1\|348597\|31\|NZ_CP016552\|CRT	348597-348627	31	NZ_AP019532	Serratia symbiotica strain IS plasmid pSsyis1, complete sequence	5706-5736	8	0.742
NZ_CP016552_2	2.3\|348730\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	348730-348758	29	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	320675-320703	8	0.724
NZ_CP016552_2	2.3\|348730\|29\|NZ_CP016552\|CRT,CRISPRCasFinder	348730-348758	29	NZ_CP014527	Haematospirillum jordaniae strain H5569 plasmid unnamed 2, complete sequence	237072-237100	8	0.724
NZ_CP016552_2	2.4\|348795\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348795-348824	30	NZ_CP014942	Rhodococcus sp. BH4 plasmid, complete sequence	426496-426525	8	0.733
NZ_CP016552_2	2.17\|349649\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349649-349678	30	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	1165935-1165964	8	0.733
NZ_CP016552_2	2.19\|348731\|29\|NZ_CP016552\|PILER-CR	348731-348759	29	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	320675-320703	8	0.724
NZ_CP016552_2	2.19\|348731\|29\|NZ_CP016552\|PILER-CR	348731-348759	29	NZ_CP014527	Haematospirillum jordaniae strain H5569 plasmid unnamed 2, complete sequence	237072-237100	8	0.724
NZ_CP016552_2	2.20\|348797\|30\|NZ_CP016552\|PILER-CR	348797-348826	30	NZ_CP014942	Rhodococcus sp. BH4 plasmid, complete sequence	426496-426525	8	0.733
NZ_CP016552_2	2.6\|348927\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348927-348956	30	NC_022551	Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence	2589-2618	9	0.7
NZ_CP016552_2	2.6\|348927\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348927-348956	30	CP054911	Pantoea ananatis strain FDAARGOS_680 plasmid unnamed3, complete sequence	170067-170096	9	0.7
NZ_CP016552_2	2.6\|348927\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348927-348956	30	NZ_CP016898	Acinetobacter soli strain GFJ2 plasmid pGFJ2, complete sequence	33496-33525	9	0.7
NZ_CP016552_2	2.8\|349059\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	349059-349088	30	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	302602-302631	9	0.7
NZ_CP016552_2	2.8\|349059\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	349059-349088	30	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	501048-501077	9	0.7
NZ_CP016552_2	2.22\|348931\|30\|NZ_CP016552\|PILER-CR	348931-348960	30	NC_022551	Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence	2589-2618	9	0.7
NZ_CP016552_2	2.22\|348931\|30\|NZ_CP016552\|PILER-CR	348931-348960	30	CP054911	Pantoea ananatis strain FDAARGOS_680 plasmid unnamed3, complete sequence	170067-170096	9	0.7
NZ_CP016552_2	2.22\|348931\|30\|NZ_CP016552\|PILER-CR	348931-348960	30	NZ_CP016898	Acinetobacter soli strain GFJ2 plasmid pGFJ2, complete sequence	33496-33525	9	0.7
NZ_CP016552_2	2.24\|349065\|30\|NZ_CP016552\|PILER-CR	349065-349094	30	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	302602-302631	9	0.7
NZ_CP016552_2	2.24\|349065\|30\|NZ_CP016552\|PILER-CR	349065-349094	30	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	501048-501077	9	0.7
NZ_CP016552_2	2.1\|348597\|31\|NZ_CP016552\|CRT	348597-348627	31	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1560917-1560947	10	0.677
NZ_CP016552_2	2.6\|348927\|30\|NZ_CP016552\|CRT,CRISPRCasFinder	348927-348956	30	KT997872	Uncultured Mediterranean phage uvDeep-CGR2-AD8-C175, complete genome	13736-13765	10	0.667
NZ_CP016552_2	2.12\|349320\|30\|NZ_CP016552\|CRT,CRISPRCasFinder,PILER-CR	349320-349349	30	CP053577	Salmonella enterica strain 2012K-0845 plasmid unnamed2, complete sequence	111859-111888	10	0.667
NZ_CP016552_2	2.22\|348931\|30\|NZ_CP016552\|PILER-CR	348931-348960	30	KT997872	Uncultured Mediterranean phage uvDeep-CGR2-AD8-C175, complete genome	13736-13765	10	0.667
NZ_CP016552_8	8.2\|1955569\|35\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1955569-1955603	35	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	506567-506601	10	0.714
NZ_CP016552_7	7.6\|1840465\|35\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1840465-1840499	35	NZ_CP022992	Paraburkholderia aromaticivorans strain BN5 plasmid pBN2, complete sequence	405532-405566	11	0.686
NZ_CP016552_7	7.6\|1840465\|35\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1840465-1840499	35	NC_015851	Acidithiobacillus caldus SM-1 megaplasmid, complete sequence	215630-215664	11	0.686
NZ_CP016552_8	8.22\|1956878\|37\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1956878-1956914	37	NC_011880	Cyanothece sp. PCC 7425 plasmid pP742501, complete sequence	174724-174760	12	0.676
NZ_CP016552_8	8.22\|1956878\|37\|NZ_CP016552\|CRISPRCasFinder,CRT,PILER-CR	1956878-1956914	37	NC_011885	Cyanothece sp. PCC 7425 plasmid pP742502, complete sequence	108826-108862	12	0.676

1. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to CP011833 (Geobacillus sp. 12AMOR1 plasmid pGARCT, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

2. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP025075 ([Bacillus] caldolyticus strain NEB414 plasmid pBcl1, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

3. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP014336 (Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

4. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP014336 (Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

5. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to CP008904 (Geobacillus sp. LC300 plasmid pGt35, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

6. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_006509 (Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

7. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to CP017693 (Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

8. spacer 2.9|349125|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_006509 (Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence) position: , mismatch: 0, identity: 1.0

ttcgctgtttattccttttcatcaagctt	CRISPR spacer
ttcgctgtttattccttttcatcaagctt	Protospacer
*****************************

9. spacer 2.9|349125|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_010420 (Geobacillus stearothermophilus plasmid pGS18, strain 18) position: , mismatch: 0, identity: 1.0

ttcgctgtttattccttttcatcaagctt	CRISPR spacer
ttcgctgtttattccttttcatcaagctt	Protospacer
*****************************

10. spacer 2.11|349255|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP017691 (Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence) position: , mismatch: 0, identity: 1.0

atgaaaaaagagggacaaatgccctctag	CRISPR spacer
atgaaaaaagagggacaaatgccctctag	Protospacer
*****************************

11. spacer 2.11|349255|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP017691 (Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence) position: , mismatch: 0, identity: 1.0

atgaaaaaagagggacaaatgccctctag	CRISPR spacer
atgaaaaaagagggacaaatgccctctag	Protospacer
*****************************

12. spacer 2.14|349451|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to CP008904 (Geobacillus sp. LC300 plasmid pGt35, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttgtcgaaccaacagacgcatcgattc	CRISPR spacer
gtgttgtcgaaccaacagacgcatcgattc	Protospacer
******************************

13. spacer 2.14|349451|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to CP008904 (Geobacillus sp. LC300 plasmid pGt35, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttgtcgaaccaacagacgcatcgattc	CRISPR spacer
gtgttgtcgaaccaacagacgcatcgattc	Protospacer
******************************

14. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to CP011833 (Geobacillus sp. 12AMOR1 plasmid pGARCT, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

15. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to NZ_CP025075 ([Bacillus] caldolyticus strain NEB414 plasmid pBcl1, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

16. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to NZ_CP014336 (Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

17. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to NZ_CP014336 (Geobacillus thermoleovorans strain KCTC 3570 plasmid pLDW-1, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

18. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to CP008904 (Geobacillus sp. LC300 plasmid pGt35, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

19. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to NC_006509 (Geobacillus kaustophilus HTA426 plasmid pHTA426, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

20. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to CP017693 (Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence) position: , mismatch: 0, identity: 1.0

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtattccac	Protospacer
******************************

21. spacer 6.3|1831851|37|NZ_CP016552|CRISPRCasFinder,PILER-CR matches to AB823818 (Phage phi OH2 DNA, complete genome) position: , mismatch: 0, identity: 1.0

aagacccatttgcaaatcgccctggctaaacggctca	CRISPR spacer
aagacccatttgcaaatcgccctggctaaacggctca	Protospacer
*************************************

22. spacer 6.7|1831851|38|NZ_CP016552|CRT matches to AB823818 (Phage phi OH2 DNA, complete genome) position: , mismatch: 0, identity: 1.0

aagacccatttgcaaatcgccctggctaaacggctcat	CRISPR spacer
aagacccatttgcaaatcgccctggctaaacggctcat	Protospacer
**************************************

23. spacer 8.6|1955831|39|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 0, identity: 1.0

gaacatgacaaccgcttctttcaagtcacctacaatgat	CRISPR spacer
gaacatgacaaccgcttctttcaagtcacctacaatgat	Protospacer
***************************************

24. spacer 8.7|1955899|35|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 0, identity: 1.0

cttttctcaatcgctcgatgtcgcgtagatactca	CRISPR spacer
cttttctcaatcgctcgatgtcgcgtagatactca	Protospacer
***********************************

25. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_013412 (Geobacillus sp. Y412MC61, complete sequence) position: , mismatch: 1, identity: 0.967

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtactccac	Protospacer
************************.*****

26. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_014916 (Geobacillus sp. Y412MC52 plasmid pGYMC5201, complete sequence) position: , mismatch: 1, identity: 0.967

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtactccac	Protospacer
************************.*****

27. spacer 2.7|348993|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_041918 (Geobacillus phage TP-84, complete genome) position: , mismatch: 1, identity: 0.967

catcgcaccagacatgtcgccgcgaatgaa	CRISPR spacer
catcgcacccgacatgtcgccgcgaatgaa	Protospacer
********* ********************

28. spacer 2.11|349255|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_010420 (Geobacillus stearothermophilus plasmid pGS18, strain 18) position: , mismatch: 1, identity: 0.966

atgaaaaaagagggacaaatgccctctag	CRISPR spacer
atgaaaaaagagggccaaatgccctctag	Protospacer
************** **************

29. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to NC_013412 (Geobacillus sp. Y412MC61, complete sequence) position: , mismatch: 1, identity: 0.967

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtactccac	Protospacer
************************.*****

30. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to NC_014916 (Geobacillus sp. Y412MC52 plasmid pGYMC5201, complete sequence) position: , mismatch: 1, identity: 0.967

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
gacatagccggaatgctcgtcgtactccac	Protospacer
************************.*****

31. spacer 2.23|348998|30|NZ_CP016552|PILER-CR matches to NC_041918 (Geobacillus phage TP-84, complete genome) position: , mismatch: 1, identity: 0.967

catcgcaccagacatgtcgccgcgaatgaa	CRISPR spacer
catcgcacccgacatgtcgccgcgaatgaa	Protospacer
********* ********************

32. spacer 7.6|1840465|35|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 1, identity: 0.971

gaaggcatggcggagatcgtgcaaggacaagccta	CRISPR spacer
gaaggcatggctgagatcgtgcaaggacaagccta	Protospacer
*********** ***********************

33. spacer 8.1|1955519|21|NZ_CP016552|CRISPRCasFinder,CRT matches to NZ_CP049914 (Vibrio sp. HDW18 plasmid p_unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

gacttcggcgatgaaatggtt	CRISPR spacer
gccttcggcgatgaaatggtt	Protospacer
* *******************

34. spacer 2.11|349255|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_009329 (Geobacillus thermodenitrificans NG80-2 plasmid pLW1071, complete sequence) position: , mismatch: 2, identity: 0.931

atgaaaaaagagggacaaatgccctctag	CRISPR spacer
atgaaaaaagagggccaaatgccctctgg	Protospacer
************** ************.*

35. spacer 2.15|349517|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NC_012794 (Geobacillus sp. WCH70 plasmid pWCH7001, complete sequence) position: , mismatch: 2, identity: 0.933

ttcaccttgaaaggggcttgttgcttttaa	CRISPR spacer
ctcaccttgaaaggggcttgctgcttttaa	Protospacer
.*******************.*********

36. spacer 2.15|349517|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NC_009329 (Geobacillus thermodenitrificans NG80-2 plasmid pLW1071, complete sequence) position: , mismatch: 2, identity: 0.933

ttcaccttgaaaggggcttgttgcttttaa	CRISPR spacer
ctcaccttgaaaggggcttattgcttttaa	Protospacer
.******************.**********

37. spacer 2.15|349517|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP017691 (Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence) position: , mismatch: 2, identity: 0.933

ttcaccttgaaaggggcttgttgcttttaa	CRISPR spacer
ctcaccatgaaaggggcttgttgcttttaa	Protospacer
.***** ***********************

38. spacer 2.15|349517|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020031 (Geobacillus thermodenitrificans strain T12 plasmid pGeo12a, complete sequence) position: , mismatch: 2, identity: 0.933

ttcaccttgaaaggggcttgttgcttttaa	CRISPR spacer
ctcaccttgaaaggggcttattgcttttaa	Protospacer
.******************.**********

39. spacer 2.15|349517|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP020032 (Geobacillus thermodenitrificans strain T12 plasmid pGeo12b, complete sequence) position: , mismatch: 2, identity: 0.933

ttcaccttgaaaggggcttgttgcttttaa	CRISPR spacer
ctcaccttgaaaggggcttgctgcttttaa	Protospacer
.*******************.*********

40. spacer 2.15|349517|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP049704 (Parageobacillus toebii NBRC 107807 strain DSM 14590 plasmid pDSM14590, complete sequence) position: , mismatch: 2, identity: 0.933

ttcaccttgaaaggggcttgttgcttttaa	CRISPR spacer
ctcaccttgaaaggggcttgctgcttttaa	Protospacer
.*******************.*********

41. spacer 8.4|1955699|37|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 2, identity: 0.946

ttggcaagtgccgttcgttgtgacatgtctgtttcca	CRISPR spacer
ttggcaagtgccgttcgtcgtgacatgcctgtttcca	Protospacer
******************.********.*********

42. spacer 2.3|348730|29|NZ_CP016552|CRT,CRISPRCasFinder matches to JX676771 (Pseudomonas phage AF, complete genome) position: , mismatch: 6, identity: 0.793

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
ctgatcagttcctcgatctcagccagcag	Protospacer
..***** ************ ****.* *

43. spacer 2.6|348927|30|NZ_CP016552|CRT,CRISPRCasFinder matches to KC699836 (Bacillus phage SIOphi, partial genome) position: , mismatch: 6, identity: 0.8

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
tgaaaacttgtatgaaaaattaatgttgaa	Protospacer
 **.***** *****************..

44. spacer 2.6|348927|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP043834 (Bacillus sp. BS98 plasmid unnamed4) position: , mismatch: 6, identity: 0.8

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
agagaagttttatgaaaagttaatagaaga	Protospacer
****** ***********.*****.  **

45. spacer 2.6|348927|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP020436 (Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
agagaagttttatgaaaagttaatagaaga	Protospacer
****** ***********.*****.  **

46. spacer 2.16|349583|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to MT457553 (Shewanella phage Thanatos-2, complete genome) position: , mismatch: 6, identity: 0.8

ttgtttaagcgcctggacattattgacgct	CRISPR spacer
ttgtttaagcgcctggatattcttacggcc	Protospacer
*****************.*** **.  **.

47. spacer 2.19|348731|29|NZ_CP016552|PILER-CR matches to JX676771 (Pseudomonas phage AF, complete genome) position: , mismatch: 6, identity: 0.793

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
ctgatcagttcctcgatctcagccagcag	Protospacer
..***** ************ ****.* *

48. spacer 2.22|348931|30|NZ_CP016552|PILER-CR matches to KC699836 (Bacillus phage SIOphi, partial genome) position: , mismatch: 6, identity: 0.8

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
tgaaaacttgtatgaaaaattaatgttgaa	Protospacer
 **.***** *****************..

49. spacer 2.22|348931|30|NZ_CP016552|PILER-CR matches to NZ_CP043834 (Bacillus sp. BS98 plasmid unnamed4) position: , mismatch: 6, identity: 0.8

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
agagaagttttatgaaaagttaatagaaga	Protospacer
****** ***********.*****.  **

50. spacer 2.22|348931|30|NZ_CP016552|PILER-CR matches to NZ_CP020436 (Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
agagaagttttatgaaaagttaatagaaga	Protospacer
****** ***********.*****.  **

51. spacer 2.1|348597|31|NZ_CP016552|CRT matches to NC_047750 (Mannheimia phage vB_MhM_1127AP1, complete genome) position: , mismatch: 7, identity: 0.774

gacgaccggcaacgcgatcactattggcaag	CRISPR spacer
gcgtagcggcaacgccagcactattggcaaa	Protospacer
*   * ********* * ************.

52. spacer 2.1|348597|31|NZ_CP016552|CRT matches to NC_028898 (Mannheimia phage vB_MhM_587AP1, complete genome) position: , mismatch: 7, identity: 0.774

gacgaccggcaacgcgatcactattggcaag	CRISPR spacer
gcgtagcggcaacgccagcactattggcaaa	Protospacer
*   * ********* * ************.

53. spacer 2.3|348730|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 7, identity: 0.759

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
gcaatcactgcctcgatctccgcctccat	Protospacer
 *.****** **************  *

54. spacer 2.9|349125|29|NZ_CP016552|CRT,CRISPRCasFinder matches to CP011076 (Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.759

ttcgctgtttattccttttcatcaagctt	CRISPR spacer
gttgctgtttgttccttttcatcaattga	Protospacer
 *.*******.************** .

55. spacer 2.10|349190|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP013632 (Rhizobium sp. N324 plasmid pRspN324b, complete sequence) position: , mismatch: 7, identity: 0.759

tcatcagaccccgagccactgcgaataag	CRISPR spacer
acatcagagcccgagccacggcgagcatc	Protospacer
 ******* ********** ****..*

56. spacer 2.14|349451|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP031942 (Nostoc sphaeroides strain Kutzing En plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

gtgttgtcgaaccaacagacgcatcgattc	CRISPR spacer
ttgttatcgaaccaacagacacatctaaaa	Protospacer
 ****.**************.**** *

57. spacer 2.14|349451|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP031942 (Nostoc sphaeroides strain Kutzing En plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

gtgttgtcgaaccaacagacgcatcgattc	CRISPR spacer
ttgttatcgaaccaacagacacatctaaaa	Protospacer
 ****.**************.**** *

58. spacer 2.17|349649|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to MN694433 (Marine virus AFVG_250M1159, complete genome) position: , mismatch: 7, identity: 0.767

tcgtctttcacccgatcaacaagagtttta	CRISPR spacer
ccacgtttcacccgatcaacaagagcttgt	Protospacer
.*.. ********************.**

59. spacer 2.17|349649|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NC_029106 (Achromobacter phage phiAxp-2, complete genome) position: , mismatch: 7, identity: 0.767

tcgtctttcacccgatcaacaagagtttta	CRISPR spacer
acatctttcacccgatcaacacgactgaga	Protospacer
 *.****************** ** *   *

60. spacer 2.19|348731|29|NZ_CP016552|PILER-CR matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 7, identity: 0.759

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
gcaatcactgcctcgatctccgcctccat	Protospacer
 *.****** **************  *

61. spacer 2.1|348597|31|NZ_CP016552|CRT matches to NZ_AP019532 (Serratia symbiotica strain IS plasmid pSsyis1, complete sequence) position: , mismatch: 8, identity: 0.742

gacgaccggcaacgcgatcactattggcaag	CRISPR spacer
ataaaacagcaacgggatcactactggcaag	Protospacer
.  .* *.****** ********.*******

62. spacer 2.3|348730|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 8, identity: 0.724

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
tcgatcacttcctcgacatccgcatggac	Protospacer
****************. *****  .

63. spacer 2.3|348730|29|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP014527 (Haematospirillum jordaniae strain H5569 plasmid unnamed 2, complete sequence) position: , mismatch: 8, identity: 0.724

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
tcgatcaattcctcgatcttcgctgttgc	Protospacer
******* ***********.***.. .

64. spacer 2.4|348795|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP014942 (Rhodococcus sp. BH4 plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
atcggtgccggaatgctcgtcgtactctgc	Protospacer
. *.  ******************.**..*

65. spacer 2.17|349649|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 8, identity: 0.733

tcgtctttcacccgatcaacaagagtttta	CRISPR spacer
tcttctttcacccgatcgacaagatcacct	Protospacer
** **************.****** . ..

66. spacer 2.19|348731|29|NZ_CP016552|PILER-CR matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 8, identity: 0.724

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
tcgatcacttcctcgacatccgcatggac	Protospacer
****************. *****  .

67. spacer 2.19|348731|29|NZ_CP016552|PILER-CR matches to NZ_CP014527 (Haematospirillum jordaniae strain H5569 plasmid unnamed 2, complete sequence) position: , mismatch: 8, identity: 0.724

tcgatcacttcctcgatctccgccaaccg	CRISPR spacer
tcgatcaattcctcgatcttcgctgttgc	Protospacer
******* ***********.***.. .

68. spacer 2.20|348797|30|NZ_CP016552|PILER-CR matches to NZ_CP014942 (Rhodococcus sp. BH4 plasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gacatagccggaatgctcgtcgtattccac	CRISPR spacer
atcggtgccggaatgctcgtcgtactctgc	Protospacer
. *.  ******************.**..*

69. spacer 2.6|348927|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_022551 (Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
ttattttttttatgaaaaattaatattaat	Protospacer
  *   .*****************.***..

70. spacer 2.6|348927|30|NZ_CP016552|CRT,CRISPRCasFinder matches to CP054911 (Pantoea ananatis strain FDAARGOS_680 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
agagaacttttatgaaaatttccacccgcc	Protospacer
****************** **    ... *

71. spacer 2.6|348927|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP016898 (Acinetobacter soli strain GFJ2 plasmid pGFJ2, complete sequence) position: , mismatch: 9, identity: 0.7

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
gatcaacttttatgaaaaattcattttctt	Protospacer
..  ***************** ** **  .

72. spacer 2.8|349059|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

tcatcgatcatcacccatctcttcaacctt	CRISPR spacer
gacttcctcatcacccatttcttcaacccg	Protospacer
   *.  ***********.*********.

73. spacer 2.8|349059|30|NZ_CP016552|CRT,CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 9, identity: 0.7

tcatcgatcatcacccatctcttcaacctt	CRISPR spacer
gacttcgtcatcacccatttcttcaacccg	Protospacer
   *. .***********.*********.

74. spacer 2.22|348931|30|NZ_CP016552|PILER-CR matches to NC_022551 (Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
ttattttttttatgaaaaattaatattaat	Protospacer
  *   .*****************.***..

75. spacer 2.22|348931|30|NZ_CP016552|PILER-CR matches to CP054911 (Pantoea ananatis strain FDAARGOS_680 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
agagaacttttatgaaaatttccacccgcc	Protospacer
****************** **    ... *

76. spacer 2.22|348931|30|NZ_CP016552|PILER-CR matches to NZ_CP016898 (Acinetobacter soli strain GFJ2 plasmid pGFJ2, complete sequence) position: , mismatch: 9, identity: 0.7

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
gatcaacttttatgaaaaattcattttctt	Protospacer
..  ***************** ** **  .

77. spacer 2.24|349065|30|NZ_CP016552|PILER-CR matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

tcatcgatcatcacccatctcttcaacctt	CRISPR spacer
gacttcctcatcacccatttcttcaacccg	Protospacer
   *.  ***********.*********.

78. spacer 2.24|349065|30|NZ_CP016552|PILER-CR matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 9, identity: 0.7

tcatcgatcatcacccatctcttcaacctt	CRISPR spacer
gacttcgtcatcacccatttcttcaacccg	Protospacer
   *. .***********.*********.

79. spacer 2.1|348597|31|NZ_CP016552|CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 10, identity: 0.677

gacgaccggcaacgcgatcactattggcaag	CRISPR spacer
cgaagccggcaacgcgatcacgatcggcttc	Protospacer
 . ..**************** **.***

80. spacer 2.6|348927|30|NZ_CP016552|CRT,CRISPRCasFinder matches to KT997872 (Uncultured Mediterranean phage uvDeep-CGR2-AD8-C175, complete genome) position: , mismatch: 10, identity: 0.667

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
tctcctcttttatgaaaaattaattttttt	Protospacer
      ****************** **  .

81. spacer 2.12|349320|30|NZ_CP016552|CRT,CRISPRCasFinder,PILER-CR matches to CP053577 (Salmonella enterica strain 2012K-0845 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.667

acagcgaatgaagggtgatctgtatgattg	CRISPR spacer
gcagcgaatgaagggtgatgtgccacggga	Protospacer
.****************** **.   .  .

82. spacer 2.22|348931|30|NZ_CP016552|PILER-CR matches to KT997872 (Uncultured Mediterranean phage uvDeep-CGR2-AD8-C175, complete genome) position: , mismatch: 10, identity: 0.667

agagaacttttatgaaaaattaatgttagc	CRISPR spacer
tctcctcttttatgaaaaattaattttttt	Protospacer
      ****************** **  .

83. spacer 8.2|1955569|35|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 10, identity: 0.714

ggaacggtgctcgccagcctgccgcttgaaatcgg--	CRISPR spacer
aatccggtgctcgccagcctgatgcttgag--cagtt	Protospacer
..  ***************** .******.  *.*

84. spacer 7.6|1840465|35|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022992 (Paraburkholderia aromaticivorans strain BN5 plasmid pBN2, complete sequence) position: , mismatch: 11, identity: 0.686

gaaggcatggcggagatcgtgcaaggacaagccta	CRISPR spacer
gaatgcgtggcggagatcgtgcaagtgcggatacg	Protospacer
*** **.****************** .*.... ..

85. spacer 7.6|1840465|35|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_015851 (Acidithiobacillus caldus SM-1 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.686

gaaggcatggcggagatcgtgcaaggacaagccta	CRISPR spacer
gaaggcatggcgtaggtcgtgcaagcgcggcgacg	Protospacer
************ **.********* .*..   ..

86. spacer 8.22|1956878|37|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_011880 (Cyanothece sp. PCC 7425 plasmid pP742501, complete sequence) position: , mismatch: 12, identity: 0.676

gattcttcacagaacgaagaacagaagcaagaaaacc	CRISPR spacer
ggcaaagagttgagcgaacaacagaagcaagaaaacc	Protospacer
*..     .. **.**** ******************

87. spacer 8.22|1956878|37|NZ_CP016552|CRISPRCasFinder,CRT,PILER-CR matches to NC_011885 (Cyanothece sp. PCC 7425 plasmid pP742502, complete sequence) position: , mismatch: 12, identity: 0.676

gattcttcacagaacgaagaacagaagcaagaaaacc	CRISPR spacer
ggcaaagagttgagcgaacaacagaagcaagaaaacc	Protospacer
*..     .. **.**** ******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

170098 : 306160

103

Bacillus_phage(13.79%)

integrase,protease,coat,transposase,tRNA

attL 233450:233509|attR 275073:275191

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095858728.1\|170098_171232_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_095858729.1\|171346_172231_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011229683.1\|172615_173071_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_033007523.1\|173483_174116_+	hypothetical protein	NA	NA	NA	NA
WP_095858731.1\|174389_174947_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	1.3e-52	60.8
WP_095858732.1\|175805_176558_-	TatD family hydrolase	NA	NA	NA	NA
WP_095860167.1\|176607_177981_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_095858733.1\|178404_179652_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	1.9e-62	36.9
WP_095858734.1\|179948_181496_+	L-glutamate gamma-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_095858735.1\|181566_182775_+	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	1.1e-30	29.5
WP_033016526.1\|182926_183535_+	DedA family protein	NA	NA	NA	NA
WP_095858736.1\|183597_184587_-	iron ABC transporter permease	NA	NA	NA	NA
WP_095858737.1\|184583_185591_-	iron ABC transporter permease	NA	NA	NA	NA
WP_095858738.1\|185658_186585_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015373767.1\|186591_187383_-	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	3.2e-15	30.3
WP_095858739.1\|189201_189906_+	DsbA family oxidoreductase	NA	NA	NA	NA
WP_081107437.1\|189991_190480_-	hypothetical protein	NA	NA	NA	NA
WP_094239465.1\|191758_192397_+\|transposase	IS607 family transposase	Q331V0	Clostridium_botulinum_C_phage	7.9e-25	34.5
WP_095858740.1\|192411_193965_+	hypothetical protein	NA	NA	NA	NA
WP_095858741.1\|194383_196345_-	LTA synthase family protein	W6LM83	Streptococcus_phage	9.2e-141	45.7
WP_033010305.1\|196804_198142_+	ATP synthase subunit J	NA	NA	NA	NA
WP_095858742.1\|198526_200362_+	APC family permease	NA	NA	NA	NA
WP_095858743.1\|200467_201106_+	sporulation membrane protein YtaF	NA	NA	NA	NA
WP_095858744.1\|201169_202153_+	sporulation protein	NA	NA	NA	NA
WP_095860168.1\|202301_202808_+\|coat	spore coat protein	NA	NA	NA	NA
WP_033010289.1\|203508_204330_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_033016518.1\|204735_205809_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_095858745.1\|206137_206866_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_095858746.1\|206876_207488_+	DedA family protein	NA	NA	NA	NA
WP_055359165.1\|207484_208627_+	galactosyldiacylglycerol synthase	NA	NA	NA	NA
WP_033016543.1\|208787_209882_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_095858747.1\|209897_211274_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_095858748.1\|211346_212069_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_095858749.1\|212130_213534_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.2e-67	36.9
WP_033010298.1\|213545_214163_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_033010299.1\|214281_214671_+	holo-ACP synthase	NA	NA	NA	NA
WP_044743921.1\|214750_215770_+	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
WP_095860169.1\|216012_217179_+	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	1.3e-30	30.2
WP_033010302.1\|217293_217575_+	hypothetical protein	NA	NA	NA	NA
WP_003253417.1\|217579_217930_+	type II toxin-antitoxin system endoribonuclease NdoA	A0A2P0ZKX3	Lactobacillus_phage	2.0e-14	38.6
WP_095858750.1\|218472_220635_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_095858751.1\|220692_220806_-	cortex morphogenetic protein CmpA	NA	NA	NA	NA
WP_047817690.1\|220899_221418_+	SprT family protein	U5J9G1	Bacillus_phage	5.6e-05	25.6
WP_095858752.1\|223444_224389_+	hypothetical protein	NA	NA	NA	NA
WP_095858753.1\|224352_225231_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_095858754.1\|225374_225689_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
233450:233509	attL	NA	NA	NA	NA
WP_033010045.1\|233793_234252_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_095858756.1\|234248_234989_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_033010040.1\|234948_235401_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_050368105.1\|235397_236411_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.2e-70	44.8
WP_033016753.1\|237161_239093_-	ABC-F type ribosomal protection protein	A0A2K9L3Z8	Tupanvirus	2.1e-60	34.1
WP_095860170.1\|239188_239677_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_033010037.1\|239692_240334_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_095858757.1\|240351_240504_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_095860171.1\|240524_241268_+	twin-arginine translocase subunit TatC	NA	NA	NA	NA
WP_047818438.1\|241531_243046_-\|transposase	IS1182 family transposase	Q9MBP7	Staphylococcus_prophage	2.5e-77	36.5
WP_095858758.1\|243218_243398_-	YdiK family protein	NA	NA	NA	NA
WP_044742383.1\|243394_244129_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_033010033.1\|244489_244774_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.1e-18	51.6
WP_033010031.1\|244892_246509_+	chaperonin GroEL	A0A219YK78	uncultured_virus	3.4e-165	59.1
WP_050497516.1\|246587_246770_-\|integrase	tyrosine-type recombinase/integrase	S6C485	Thermus_phage	1.0e-22	100.0
WP_011229657.1\|248106_249765_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_095858759.1\|249948_251109_+	hypothetical protein	Q5YA51	Bacillus_phage	1.1e-08	43.4
WP_091704432.1\|251123_251582_+	hypothetical protein	NA	NA	NA	NA
WP_095858760.1\|252053_252572_-	hypothetical protein	NA	NA	NA	NA
WP_095858761.1\|252586_253957_+	class II fumarate hydratase	NA	NA	NA	NA
WP_095858762.1\|254091_255315_-	divalent metal cation transporter	NA	NA	NA	NA
WP_095858763.1\|255443_256400_+	MoxR family ATPase	NA	NA	NA	NA
WP_095858764.1\|256405_257581_+	DUF58 domain-containing protein	NA	NA	NA	NA
WP_095858765.1\|257577_259740_+	DUF4129 domain-containing protein	NA	NA	NA	NA
WP_095860172.1\|260347_261880_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.6e-18	30.1
WP_095858766.1\|262160_263486_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	6.8e-55	33.1
WP_095860173.1\|266233_266704_-	YjdJ family protein	NA	NA	NA	NA
WP_095858767.1\|267122_267683_+	hypothetical protein	NA	NA	NA	NA
WP_095858768.1\|267703_268582_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_095858720.1\|271662_271890_+	hypothetical protein	NA	NA	NA	NA
WP_095858769.1\|275430_275874_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
275073:275191	attR	NA	NA	NA	NA
WP_033009939.1\|276233_276722_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.3e-22	42.0
WP_095860174.1\|276648_277863_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_095858770.1\|277859_279155_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.2e-18	34.3
WP_033009943.1\|279230_279959_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	9.6e-43	41.9
WP_049624734.1\|279946_280201_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_033016682.1\|280197_280884_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_050368120.1\|280867_283096_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-170	42.8
WP_033009946.1\|283071_284484_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.2e-50	35.1
WP_095858771.1\|284549_285590_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FC27	Synechococcus_phage	2.1e-67	43.9
WP_033009948.1\|285586_286219_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	1.2e-25	37.4
WP_044744031.1\|286181_287720_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	6.0e-79	53.0
WP_033009953.1\|289390_289636_-	DUF2892 domain-containing protein	NA	NA	NA	NA
WP_095858772.1\|289730_291476_+	adenine deaminase	NA	NA	NA	NA
WP_095858773.1\|291494_292520_+	DUF3048 domain-containing protein	NA	NA	NA	NA
WP_033009956.1\|292622_292949_+	hypothetical protein	NA	NA	NA	NA
WP_033009957.1\|293048_293750_+	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_033016687.1\|293778_295953_+	DNA helicase PcrA	A7KV33	Bacillus_phage	1.5e-128	40.7
WP_033016671.1\|295974_297987_+	NAD-dependent DNA ligase LigA	A0A289ZTZ3	Serratia_phage	2.1e-108	40.0
WP_095858774.1\|297983_299207_+	CamS family sex pheromone protein	NA	NA	NA	NA
WP_095858775.1\|299447_300002_+	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
WP_050368127.1\|300490_301267_-	VOC family protein	NA	NA	NA	NA
WP_033016666.1\|301296_301845_-	hypothetical protein	NA	NA	NA	NA
WP_095858776.1\|302014_302590_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_014194780.1\|302955_303246_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_050368129.1\|303258_304716_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_095858777.1\|304729_306160_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA

DBSCAN-SWA_2

318463 : 374806

Rhodobacter_phage(12.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015864903.1\|318463_319717_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6
WP_095858787.1\|319869_320415_-\|transposase	transposase	NA	NA	NA	NA
WP_050483815.1\|320812_321676_+	polyprenyl synthetase	NA	NA	NA	NA
WP_013144165.1\|321695_321851_+	competence pheromone ComX	NA	NA	NA	NA
WP_095858789.1\|321857_324122_+	histidine kinase	NA	NA	NA	NA
WP_095858790.1\|324147_324819_+	response regulator transcription factor	NA	NA	NA	NA
WP_020756630.1\|324967_325450_+	hypothetical protein	NA	NA	NA	NA
WP_101878866.1\|325465_326368_+	hypothetical protein	NA	NA	NA	NA
WP_095860175.1\|326604_327087_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.0e-16	32.2
WP_095858791.1\|328138_329626_-	PH domain-containing protein	NA	NA	NA	NA
WP_095858792.1\|329644_330145_-	PH domain-containing protein	NA	NA	NA	NA
WP_095858793.1\|334005_335496_+	TIGR02677 family protein	NA	NA	NA	NA
WP_095858794.1\|335498_336695_+	TIGR02678 family protein	NA	NA	NA	NA
WP_095858795.1\|336654_340776_+	TIGR02680 family protein	NA	NA	NA	NA
WP_095858796.1\|340772_341993_+	TIGR02679 family protein	NA	NA	NA	NA
WP_095858797.1\|342060_342438_+\|transposase	transposase	NA	NA	NA	NA
WP_015374552.1\|342855_343901_-\|transposase	IS630-like element ISBs2 family transposase	S5VXX4	Leptospira_phage	1.6e-27	27.5
WP_095858798.1\|345023_345323_-	hypothetical protein	NA	NA	NA	NA
WP_095858799.1\|345335_346619_-	peptidoglycan-binding protein	A0A0A0YSS3	Erwinia_phage	7.4e-06	59.5
WP_033016933.1\|349881_350190_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_050368140.1\|350194_351094_-	type II CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_095858800.1\|351023_354287_-	type II CRISPR RNA-guided endonuclease Cas9	NA	NA	NA	NA
WP_095860176.1\|354681_355047_+\|transposase	transposase	NA	NA	NA	NA
WP_095858801.1\|355451_355661_+	hypothetical protein	A0A1U9WQQ3	Geobacillus_phage	3.0e-26	87.0
WP_095858802.1\|355827_356712_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_042382835.1\|357744_358491_+	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_011229827.1\|358977_359202_-	hypothetical protein	NA	NA	NA	NA
WP_095858803.1\|359338_360385_+	P1 family peptidase	NA	NA	NA	NA
WP_095858804.1\|360445_361678_-	MFS transporter	NA	NA	NA	NA
WP_095858805.1\|361876_362530_-	PspA/IM30 family protein	NA	NA	NA	NA
WP_095858806.1\|362489_363014_-	hypothetical protein	NA	NA	NA	NA
WP_033024617.1\|363194_363542_+	hypothetical protein	NA	NA	NA	NA
WP_095858807.1\|363739_366049_-	YhgE/Pip domain-containing protein	NA	NA	NA	NA
WP_033011731.1\|366124_366694_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_095858808.1\|366869_368243_-	GHKL domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	2.5e-12	26.4
WP_044743566.1\|368232_368895_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-32	36.0
WP_095858809.1\|369068_370274_+	PDZ domain-containing protein	W5SAB9	Pithovirus	2.0e-13	29.0
WP_033010060.1\|370998_371751_+	hypothetical protein	NA	NA	NA	NA
WP_020958535.1\|371781_372027_+	hypothetical protein	NA	NA	NA	NA
WP_074043271.1\|372070_373462_+	hypothetical protein	NA	NA	NA	NA
WP_095858810.1\|373458_373827_+	DUF962 domain-containing protein	NA	NA	NA	NA
WP_095858811.1\|373927_374806_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

386220 : 410085

Tupanvirus(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095858816.1\|386220_386835_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_095858817.1\|388646_389012_+	hypothetical protein	NA	NA	NA	NA
WP_095858818.1\|389144_390278_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_095858819.1\|391202_392021_+	hypothetical protein	NA	NA	NA	NA
WP_095858820.1\|392115_392952_+	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_095858821.1\|392955_393816_+	S8 family serine peptidase	A0A2K9L1P3	Tupanvirus	2.2e-09	31.3
WP_095858822.1\|393834_394359_+	hypothetical protein	NA	NA	NA	NA
WP_095858823.1\|394908_396567_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_095858824.1\|397485_397872_+	hypothetical protein	NA	NA	NA	NA
WP_064213564.1\|398468_399269_-	AAA family ATPase	NA	NA	NA	NA
WP_095858825.1\|399261_400515_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	2.8e-10	25.6
WP_033011705.1\|400667_401213_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_095858826.1\|403811_404174_+	hypothetical protein	NA	NA	NA	NA
WP_158522901.1\|404398_404674_-	hypothetical protein	A0A1V0SCG6	Indivirus	8.7e-05	36.2
WP_095858828.1\|404889_405456_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011229840.1\|405762_406899_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	1.2e-31	27.1
WP_055358810.1\|407339_407708_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	6.9e-50	77.9
WP_095858829.1\|408636_410085_+\|transposase	IS66 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

662341 : 734171

Streptococcus_phage(18.18%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012749092.1\|662341_663622_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_033005228.1\|664018_664312_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_060787853.1\|664336_664756_+	PIN domain-containing protein	NA	NA	NA	NA
WP_095858950.1\|664921_668332_-	methionine synthase	A0A140XBC7	Dickeya_phage	1.3e-09	46.7
WP_095858951.1\|668324_670172_-	bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_095858952.1\|670476_670860_-	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_011230222.1\|671391_671622_+\|bacteriocin	circular bacteriocin, circularin A/uberolysin family	NA	NA	NA	NA
WP_095858953.1\|671689_673309_+	hypothetical protein	NA	NA	NA	NA
WP_011230224.1\|673322_673832_+	stage II sporulation protein M	NA	NA	NA	NA
WP_011230225.1\|674021_674672_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.6e-12	29.6
WP_095858954.1\|674794_675856_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	2.9e-40	44.4
WP_033010565.1\|675852_676662_+	ABC transporter permease	NA	NA	NA	NA
WP_095858955.1\|676658_677462_+	ABC transporter permease	NA	NA	NA	NA
WP_095858956.1\|677462_678536_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_095858957.1\|678961_679279_+	hypothetical protein	NA	NA	NA	NA
WP_095858958.1\|679622_680453_-	ABC transporter permease	NA	NA	NA	NA
WP_095858959.1\|680406_681132_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	4.2e-22	32.7
WP_095858960.1\|683317_683926_+	FMN-binding negative transcriptional regulator	NA	NA	NA	NA
WP_044743365.1\|684549_685041_-	YajQ family cyclic di-GMP-binding protein	NA	NA	NA	NA
WP_008879040.1\|685241_685373_-	DUF3941 domain-containing protein	NA	NA	NA	NA
WP_095858961.1\|685607_686702_+	Fic family protein	D7RWK9	Brochothrix_phage	3.0e-48	35.6
WP_095858962.1\|686758_687622_-	DegV family protein	NA	NA	NA	NA
WP_015374102.1\|687798_687999_-	DUF3813 domain-containing protein	NA	NA	NA	NA
WP_095858963.1\|688369_689176_-	HAD family phosphatase	NA	NA	NA	NA
WP_050368327.1\|689291_690059_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_015374106.1\|690259_690631_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	8.6e-40	61.5
WP_095860189.1\|690620_692747_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	9.7e-245	63.4
WP_095858964.1\|692969_693197_+	hypothetical protein	NA	NA	NA	NA
WP_033027956.1\|693168_693492_-	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_095858965.1\|693514_694765_-	hypothetical protein	NA	NA	NA	NA
WP_013146125.1\|694761_694971_-	DUF2249 domain-containing protein	NA	NA	NA	NA
WP_095858966.1\|694974_695208_-	DUF2249 domain-containing protein	NA	NA	NA	NA
WP_095858967.1\|695283_695976_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_095858968.1\|699047_699755_-	hypothetical protein	NA	NA	NA	NA
WP_013523134.1\|700490_700724_+	DUF2249 domain-containing protein	NA	NA	NA	NA
WP_095858969.1\|700696_701407_+	molybdenum cofactor guanylyltransferase	NA	NA	NA	NA
WP_095858970.1\|701496_702099_-	response regulator transcription factor	NA	NA	NA	NA
WP_095858971.1\|703895_704774_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_095858972.1\|704794_705436_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.5e-31	34.4
WP_020279212.1\|705451_706945_-	hypothetical protein	NA	NA	NA	NA
WP_033012619.1\|706937_707717_-	ABC transporter permease	NA	NA	NA	NA
WP_095858971.1\|707866_708745_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_095858973.1\|711404_712580_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_095858974.1\|714006_714705_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_095858975.1\|714922_715585_+	molybdate ABC transporter permease subunit	NA	NA	NA	NA
WP_095858976.1\|715639_716665_+	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_095858977.1\|716752_717460_-	iron-sulfur cluster repair di-iron protein	NA	NA	NA	NA
WP_095858978.1\|717746_718703_+	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.1e-11	32.4
WP_095858979.1\|718753_720013_+	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_095858980.1\|720009_720510_+	molybdopterin-guanine dinucleotide biosynthesis protein B	NA	NA	NA	NA
WP_011230276.1\|720506_720974_+	molybdenum cofactor biosynthesis protein MoaE	NA	NA	NA	NA
WP_011230277.1\|720970_721201_+	molybdopterin converting factor subunit 1	NA	NA	NA	NA
WP_033013772.1\|721206_721935_+	YwiC-like family protein	NA	NA	NA	NA
WP_033843279.1\|729191_729425_+	hypothetical protein	NA	NA	NA	NA
WP_020279908.1\|729872_730673_-	AAA family ATPase	NA	NA	NA	NA
WP_033011561.1\|730665_731916_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	9.7e-11	26.3
WP_033011559.1\|732057_732621_-	hypothetical protein	NA	NA	NA	NA
WP_095858981.1\|732980_734171_+\|transposase	ISL3 family transposase	A0A0A8WEF4	Clostridium_phage	1.2e-29	25.4

DBSCAN-SWA_5

741294 : 802383

Bacillus_phage(18.18%)

coat,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095858984.1\|741294_741840_+\|transposase	transposase	NA	NA	NA	NA
WP_015864903.1\|741992_743246_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6
WP_095858985.1\|743238_744039_+	AAA family ATPase	NA	NA	NA	NA
WP_095858986.1\|744349_744667_+\|transposase	transposase	NA	NA	NA	NA
WP_015864904.1\|745530_746718_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_032101163.1\|746898_747429_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_095858988.1\|748415_749294_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_095858990.1\|750921_751608_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_095858991.1\|751931_752966_+	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
WP_095858992.1\|752983_754216_+	bifunctional ornithine acetyltransferase/N-acetylglutamate synthase	NA	NA	NA	NA
WP_095858993.1\|754228_755008_+	acetylglutamate kinase	NA	NA	NA	NA
WP_095858994.1\|755011_756172_+	acetylornithine transaminase	A0A1V0SKB7	Klosneuvirus	7.6e-34	28.7
WP_095858995.1\|756260_757325_+	carbamoyl phosphate synthase small subunit	R4TGJ8	Halovirus	3.1e-58	38.4
WP_095858996.1\|757317_760446_+	carbamoyl phosphate synthase large subunit	NA	NA	NA	NA
WP_011230297.1\|760442_761381_+	ornithine carbamoyltransferase	A0A1J0F9B8	Only_Syngen_Nebraska_virus	3.5e-21	28.6
WP_011230299.1\|761565_761745_+	YjzC family protein	NA	NA	NA	NA
WP_095858997.1\|761852_764441_+	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	1.1e-125	36.4
WP_033015617.1\|764712_765285_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_095858998.1\|765375_767502_+	MMPL family transporter	NA	NA	NA	NA
WP_063210636.1\|767558_767747_-	YjzD family protein	NA	NA	NA	NA
WP_014195165.1\|767880_768621_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_014195166.1\|768655_768907_-	hypothetical protein	NA	NA	NA	NA
WP_095858999.1\|769165_770098_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_095859000.1\|770138_771377_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_011230307.1\|771521_772325_+	DUF2268 domain-containing protein	NA	NA	NA	NA
WP_011230308.1\|772461_772668_+	hypothetical protein	NA	NA	NA	NA
WP_011230309.1\|772753_773494_+	YjbA family protein	A0A0A0RP53	Bacillus_phage	9.4e-46	43.0
WP_095859001.1\|773555_774542_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_094239707.1\|774875_775250_-	DUF3899 domain-containing protein	NA	NA	NA	NA
WP_095859002.1\|775672_777325_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011230313.1\|777448_778378_+	ABC transporter permease	NA	NA	NA	NA
WP_011230314.1\|778377_779397_+	ABC transporter permease	NA	NA	NA	NA
WP_081132975.1\|779418_780480_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.5e-16	32.5
WP_011230317.1\|781495_781678_-	hypothetical protein	NA	NA	NA	NA
WP_033018851.1\|781980_782379_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_095859003.1\|782429_783089_-	TerC family protein	W8EBD0	Pseudomonas_phage	1.7e-22	38.9
WP_033010433.1\|783297_783978_+	adaptor protein MecA	NA	NA	NA	NA
WP_095859004.1\|784258_785767_+	cardiolipin synthase	NA	NA	NA	NA
WP_033015650.1\|785955_787284_+	competence protein CoiA	NA	NA	NA	NA
WP_095859005.1\|787283_789107_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	1.3e-67	28.4
WP_011230324.1\|789120_789318_-	hypothetical protein	NA	NA	NA	NA
WP_050368369.1\|789744_790638_-	DsbA family protein	NA	NA	NA	NA
WP_011230326.1\|790630_791044_-	hypothetical protein	NA	NA	NA	NA
WP_095859006.1\|791146_791770_-	lytic transglycosylase domain-containing protein	A0A1P8CWQ1	Bacillus_phage	1.8e-34	58.5
WP_095859007.1\|791766_792357_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_050368372.1\|792492_792870_+	hypothetical protein	NA	NA	NA	NA
WP_033010443.1\|793014_793653_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_033015662.1\|793649_794465_+	NAD kinase	NA	NA	NA	NA
WP_033010446.1\|794621_795536_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_095859008.1\|795930_796668_-	bis(5'-nucleosyl)-tetraphosphatase PrpE	V9QL63	Rhizobium_phage	2.2e-10	25.4
WP_095859009.1\|796867_798043_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_095859010.1\|798241_799018_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_050368376.1\|799137_799548_+	hypothetical protein	NA	NA	NA	NA
WP_095859011.1\|799672_801286_-	glycosyltransferase	NA	NA	NA	NA
WP_095859012.1\|801282_802383_-\|coat	CotS family spore coat protein	NA	NA	NA	NA

DBSCAN-SWA_6

909082 : 916125

Streptococcus_virus(33.33%)

integrase,transposase

attL 903304:903319|attR 915601:915616

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
903304:903319	attL	NA	NA	NA	NA
WP_095859072.1\|909082_910519_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1X9I6E7	Streptococcus_phage	9.8e-07	25.6
WP_095859073.1\|910686_911799_+	GerAB/ArcD/ProY family transporter	NA	NA	NA	NA
WP_095859074.1\|911970_912642_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	7.2e-69	59.2
WP_095859075.1\|912638_913076_+	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	9.6e-06	33.0
WP_095859076.1\|913075_913810_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	9.9e-56	45.4
WP_025948364.1\|913862_914360_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.0e-51	67.9
WP_095859077.1\|914413_915097_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_033005507.1\|915129_915309_-	DUF2187 family protein	NA	NA	NA	NA
WP_063211005.1\|915540_916125_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3JQ51	Bacillus_phage	3.8e-42	49.0
915601:915616	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1289508 : 1379456

Erysipelothrix_phage(27.27%)

integrase,transposase

attL 1319584:1319601|attR 1345811:1345828

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095859221.1\|1289508_1290876_+\|transposase	ISLre2-like element ISGsp3 family transposase	NA	NA	NA	NA
WP_050368573.1\|1291204_1292392_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_050368114.1\|1292666_1293893_+	MFS transporter	NA	NA	NA	NA
WP_095859224.1\|1294173_1295364_-\|transposase	ISL3 family transposase	A0A0A8WEF4	Clostridium_phage	6.2e-31	24.9
WP_095859225.1\|1295461_1295650_+\|transposase	transposase	G3MB42	Bacillus_virus	1.4e-06	63.2
WP_095859226.1\|1295714_1296152_-	hypothetical protein	NA	NA	NA	NA
WP_095859227.1\|1296977_1298138_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_095859228.1\|1298106_1298643_+	hypothetical protein	NA	NA	NA	NA
WP_095860208.1\|1299508_1299940_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	1.9e-43	59.5
WP_095859229.1\|1302428_1303157_-	hypothetical protein	NA	NA	NA	NA
WP_014195544.1\|1303473_1304640_+	hypothetical protein	NA	NA	NA	NA
WP_095859230.1\|1304702_1305470_-	dioxygenase	NA	NA	NA	NA
WP_014195546.1\|1306794_1306977_+	hypothetical protein	NA	NA	NA	NA
WP_075261456.1\|1306976_1307225_+	helix-turn-helix domain-containing protein	A0A290FZJ4	Caldibacillus_phage	5.4e-22	63.4
WP_014195549.1\|1308667_1308862_+	hypothetical protein	NA	NA	NA	NA
WP_014195550.1\|1308867_1309098_+	hypothetical protein	NA	NA	NA	NA
WP_095859231.1\|1309619_1310987_+\|transposase	ISLre2-like element ISGsp3 family transposase	NA	NA	NA	NA
WP_015374508.1\|1311199_1311535_+	hypothetical protein	NA	NA	NA	NA
WP_095859232.1\|1314482_1315253_+	DUF4391 domain-containing protein	NA	NA	NA	NA
WP_095859233.1\|1315257_1317159_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	1.0e-120	42.6
WP_095859234.1\|1317162_1320117_+	DEAD/DEAH box helicase family protein	A0A2K5B256	Erysipelothrix_phage	1.8e-217	44.3
1319584:1319601	attL	NA	NA	NA	NA
WP_095859235.1\|1320255_1321419_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_095859236.1\|1321872_1323321_+\|transposase	IS66-like element ISBst12 family transposase	NA	NA	NA	NA
WP_095859238.1\|1324961_1326020_-\|transposase	IS630 family transposase	A0A1V0SDF8	Indivirus	1.3e-11	26.5
WP_095859240.1\|1326619_1327138_+	hypothetical protein	NA	NA	NA	NA
WP_095859241.1\|1327174_1327963_+	NERD nuclease	A0A2R2ZH57	Clostridioides_phage	7.5e-25	31.3
WP_094238548.1\|1328016_1328634_+	hypothetical protein	NA	NA	NA	NA
WP_094239938.1\|1329318_1329585_+	DUF3986 family protein	NA	NA	NA	NA
WP_095859242.1\|1330186_1331809_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_094238551.1\|1331940_1332213_-	hypothetical protein	NA	NA	NA	NA
WP_094238552.1\|1332271_1333006_-	hypothetical protein	NA	NA	NA	NA
WP_094238553.1\|1333345_1334209_+\|integrase	tyrosine-type recombinase/integrase	S5M9V8	Brevibacillus_phage	3.8e-22	32.3
WP_095859243.1\|1334220_1335201_+	restriction endonuclease	NA	NA	NA	NA
WP_095859244.1\|1335706_1335931_+	hypothetical protein	NA	NA	NA	NA
WP_095859245.1\|1338216_1338396_-	hypothetical protein	NA	NA	NA	NA
WP_095859246.1\|1338566_1339085_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_064213564.1\|1345948_1346749_-	AAA family ATPase	NA	NA	NA	NA
1345811:1345828	attR	NA	NA	NA	NA
WP_095859148.1\|1346741_1347992_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	9.7e-11	26.8
WP_162494983.1\|1351122_1351446_+	hypothetical protein	NA	NA	NA	NA
WP_158522907.1\|1351453_1351738_+	ATP-binding domain-containing protein	NA	NA	NA	NA
WP_095859248.1\|1351954_1353460_+	malate:quinone oxidoreductase	NA	NA	NA	NA
WP_095859249.1\|1353738_1354293_+	YpiB family protein	NA	NA	NA	NA
WP_095859250.1\|1354397_1355519_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_095859251.1\|1355625_1356420_-	adenosylmethionine decarboxylase	NA	NA	NA	NA
WP_095859252.1\|1356556_1357396_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_095859253.1\|1357956_1358607_+	DUF975 family protein	NA	NA	NA	NA
WP_011230900.1\|1359050_1359521_+	DUF2935 domain-containing protein	NA	NA	NA	NA
WP_025951297.1\|1359588_1359906_+	YbjQ family protein	NA	NA	NA	NA
WP_025951296.1\|1360096_1360405_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_095859254.1\|1360421_1361351_+	cation transporter	NA	NA	NA	NA
WP_095859255.1\|1361381_1362278_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_095859256.1\|1362520_1364344_+	assimilatory sulfite reductase (NADPH) flavoprotein subunit	NA	NA	NA	NA
WP_095859257.1\|1364370_1366092_+	assimilatory sulfite reductase (NADPH) hemoprotein subunit	NA	NA	NA	NA
WP_095859258.1\|1366498_1367632_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_095860209.1\|1368439_1369168_-	hypothetical protein	NA	NA	NA	NA
WP_095859259.1\|1369339_1373101_+	AAA family ATPase	NA	NA	NA	NA
WP_095859260.1\|1373454_1374888_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	1.9e-106	44.2
WP_047818219.1\|1374990_1375302_-	hypothetical protein	NA	NA	NA	NA
WP_015374612.1\|1375501_1375930_+	DUF3888 domain-containing protein	NA	NA	NA	NA
WP_158522908.1\|1377096_1378353_+	MFS transporter	NA	NA	NA	NA
WP_064213576.1\|1378322_1379456_-\|transposase	IS4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

1693852 : 1740472

Escherichia_phage(25.0%)

protease,transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095859402.1\|1693852_1698013_-\|bacteriocin	bacteriocin-processing peptidase family protein	NA	NA	NA	NA
WP_014195917.1\|1698158_1698911_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_011231316.1\|1699236_1699740_-	membrane protein	NA	NA	NA	NA
WP_095859404.1\|1703587_1705057_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	1.6e-20	47.3
WP_095859405.1\|1705111_1705687_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_095859406.1\|1705662_1706367_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_068896110.1\|1706557_1707352_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_095859407.1\|1707561_1707807_-	hypothetical protein	NA	NA	NA	NA
WP_095860218.1\|1707969_1710336_-\|protease	M6 family metalloprotease domain-containing protein	NA	NA	NA	NA
WP_095859408.1\|1710602_1711901_+	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	1.4e-15	25.9
WP_033017013.1\|1712063_1712813_+	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_049626256.1\|1712987_1713389_-	hypothetical protein	NA	NA	NA	NA
WP_095859409.1\|1714561_1716430_-	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_095859410.1\|1716456_1717368_-	1-phosphofructokinase	NA	NA	NA	NA
WP_095859411.1\|1717364_1718117_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_095859412.1\|1718295_1720128_-	diguanylate cyclase	NA	NA	NA	NA
WP_095859413.1\|1720327_1720924_-	DUF5317 domain-containing protein	NA	NA	NA	NA
WP_095859415.1\|1723320_1723659_-	hypothetical protein	NA	NA	NA	NA
WP_095859416.1\|1723678_1727281_-	RHS repeat protein	NA	NA	NA	NA
WP_094238572.1\|1727475_1728276_-	AAA family ATPase	NA	NA	NA	NA
WP_012820636.1\|1728268_1729519_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	3.3e-11	26.8
WP_095859417.1\|1729661_1730225_-\|transposase	transposase	NA	NA	NA	NA
WP_095859418.1\|1736488_1737034_-\|transposase	transposase	NA	NA	NA	NA
WP_095859419.1\|1737992_1738721_-	hypothetical protein	NA	NA	NA	NA
WP_095858915.1\|1739335_1740472_+\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	2.1e-36	28.9

DBSCAN-SWA_9

1893884 : 1997768

Wolbachia_phage(18.75%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_145956580.1\|1893884_1894451_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.7e-34	45.3
WP_095859499.1\|1894754_1894997_-	hypothetical protein	NA	NA	NA	NA
WP_095859500.1\|1895229_1895859_-	VanZ family protein	NA	NA	NA	NA
WP_095859501.1\|1895929_1896313_-	hypothetical protein	NA	NA	NA	NA
WP_033845283.1\|1897413_1898862_-\|transposase	IS66-like element ISBst12 family transposase	NA	NA	NA	NA
WP_095860227.1\|1899040_1899643_+	hypothetical protein	NA	NA	NA	NA
WP_095860228.1\|1899834_1900668_+	hypothetical protein	NA	NA	NA	NA
WP_031406929.1\|1902247_1903483_+\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	6.9e-142	63.0
WP_095859502.1\|1905064_1905334_+	hypothetical protein	NA	NA	NA	NA
WP_095860229.1\|1905546_1905711_-	general secretion pathway domain protein	NA	NA	NA	NA
WP_095859503.1\|1907277_1908129_-	HAD family hydrolase	NA	NA	NA	NA
WP_095860230.1\|1908499_1908913_+	EamA family transporter	NA	NA	NA	NA
WP_095859505.1\|1909193_1910312_+	acyl-CoA desaturase	NA	NA	NA	NA
WP_095859506.1\|1910998_1911781_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_095859507.1\|1911853_1912990_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_095859508.1\|1913038_1913608_-	hypothetical protein	NA	NA	NA	NA
WP_095859509.1\|1913644_1913941_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_063329984.1\|1913953_1914319_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_015375138.1\|1914336_1914819_-	YrkE-like protein	NA	NA	NA	NA
WP_047818515.1\|1914870_1915098_-	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_013145015.1\|1915199_1915460_-	metal-sensitive transcriptional regulator	NA	NA	NA	NA
WP_095859510.1\|1915426_1915819_-	rhodanese	NA	NA	NA	NA
WP_015375142.1\|1915908_1916478_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_095859511.1\|1916563_1916782_-	hypothetical protein	NA	NA	NA	NA
WP_011231562.1\|1916807_1917197_-	hypothetical protein	NA	NA	NA	NA
WP_095859512.1\|1918876_1920133_-	MFS transporter	NA	NA	NA	NA
WP_095859513.1\|1920119_1920665_-	hypothetical protein	NA	NA	NA	NA
WP_095859514.1\|1920661_1921288_-	hypothetical protein	NA	NA	NA	NA
WP_145956581.1\|1921300_1922476_-	YcaO-like family protein	NA	NA	NA	NA
WP_095859238.1\|1922610_1923669_+\|transposase	IS630 family transposase	A0A1V0SDF8	Indivirus	1.3e-11	26.5
WP_095859516.1\|1923696_1924476_-	hypothetical protein	NA	NA	NA	NA
WP_033845283.1\|1926846_1928295_-\|transposase	IS66-like element ISBst12 family transposase	NA	NA	NA	NA
WP_095859517.1\|1928363_1929542_-	hypothetical protein	NA	NA	NA	NA
WP_033027772.1\|1929855_1931043_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_095858915.1\|1931445_1932582_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	2.1e-36	28.9
WP_095858915.1\|1933000_1934137_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	2.1e-36	28.9
WP_095859518.1\|1934554_1935691_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	1.2e-36	29.1
WP_095858787.1\|1936092_1936638_+\|transposase	transposase	NA	NA	NA	NA
WP_015864903.1\|1936790_1938044_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6
WP_015864165.1\|1938036_1938837_+	AAA family ATPase	NA	NA	NA	NA
WP_047818520.1\|1940973_1941876_-	decarboxylating 6-phosphogluconate dehydrogenase	A0A1D8KGX1	Synechococcus_phage	2.1e-55	35.9
WP_095859519.1\|1941983_1943441_-	glucose-6-phosphate dehydrogenase	M4SP85	Cyanophage	4.5e-76	34.6
WP_003252445.1\|1943977_1944343_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047818522.1\|1944862_1945537_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_033015477.1\|1945552_1946224_+	hypothetical protein	NA	NA	NA	NA
WP_081106643.1\|1946327_1946663_+	bis-aminopropyl spermidine synthase family protein	NA	NA	NA	NA
WP_095860231.1\|1947066_1947624_-	6-phospho-3-hexuloisomerase	NA	NA	NA	NA
WP_015375155.1\|1947627_1948263_-	3-hexulose-6-phosphate synthase	NA	NA	NA	NA
WP_094238572.1\|1948803_1949604_-	AAA family ATPase	NA	NA	NA	NA
WP_095858787.1\|1950020_1950566_+\|transposase	transposase	NA	NA	NA	NA
WP_015864903.1\|1950718_1951972_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6
WP_015864165.1\|1951964_1952765_+	AAA family ATPase	NA	NA	NA	NA
WP_095859417.1\|1954098_1954662_-\|transposase	transposase	NA	NA	NA	NA
WP_158522912.1\|1955124_1955379_+	hypothetical protein	NA	NA	NA	NA
WP_013144995.1\|1957205_1957469_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_044746556.1\|1957472_1958456_-	type I-B CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_013144993.1\|1958455_1958953_-	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_095859520.1\|1958967_1961145_-	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_061580951.1\|1961168_1961870_-	type I-B CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_095859521.1\|1961872_1962760_-	type I-B CRISPR-associated protein Cas7/Cst2/DevR	NA	NA	NA	NA
WP_095859522.1\|1962756_1964553_-	type I-B CRISPR-associated protein Cas8b1/Cst1	NA	NA	NA	NA
WP_095859523.1\|1964549_1965275_-	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_095859524.1\|1965591_1968048_-	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	1.4e-32	25.0
WP_033015496.1\|1968040_1968367_-	nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
WP_095859525.1\|1968567_1968795_+	hypothetical protein	NA	NA	NA	NA
WP_095859526.1\|1968871_1970203_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_095859527.1\|1971447_1971729_+	hypothetical protein	NA	NA	NA	NA
WP_095858787.1\|1971802_1972348_+\|transposase	transposase	NA	NA	NA	NA
WP_015864903.1\|1972500_1973754_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6
WP_015864165.1\|1973746_1974547_+	AAA family ATPase	NA	NA	NA	NA
WP_095859528.1\|1974801_1975068_-	protein rep	A0A286QS97	Streptococcus_phage	4.9e-05	46.0
WP_015864904.1\|1975338_1976526_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_101878873.1\|1976621_1977317_-	protein rep	NA	NA	NA	NA
WP_069304107.1\|1978531_1979284_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.2e-37	41.4
WP_033017219.1\|1979656_1979989_+	hypothetical protein	NA	NA	NA	NA
WP_095859529.1\|1980085_1981057_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_095859530.1\|1981160_1982315_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_095859531.1\|1982311_1983061_-	trehalose utilization protein ThuA	NA	NA	NA	NA
WP_095859532.1\|1983555_1984635_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_095859533.1\|1984776_1985781_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	8.6e-34	32.6
WP_095859534.1\|1986038_1986935_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_095859535.1\|1986965_1987340_+	hypothetical protein	NA	NA	NA	NA
WP_095859536.1\|1987664_1988960_-	MHS family MFS transporter	NA	NA	NA	NA
WP_095859537.1\|1989094_1989550_-	dehydratase	NA	NA	NA	NA
WP_015375219.1\|1990190_1990595_-	hypothetical protein	NA	NA	NA	NA
WP_095859538.1\|1990608_1991535_-	glutaminase A	NA	NA	NA	NA
WP_015864904.1\|1991821_1993009_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_095859539.1\|1993075_1993651_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_061580688.1\|1993786_1994248_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_095859540.1\|1994781_1995954_-	8-amino-7-oxononanoate synthase	G9E4Q1	Emiliania_huxleyi_virus	3.0e-38	28.3
WP_044743730.1\|1996160_1996343_+	small acid-soluble spore protein H	NA	NA	NA	NA
WP_095859541.1\|1996339_1996528_-	hypothetical protein	NA	NA	NA	NA
WP_069304366.1\|1996620_1996989_-	glyoxalase	NA	NA	NA	NA
WP_095859542.1\|1996985_1997768_-\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_10

2064777 : 2075715

Pandoravirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063330384.1\|2064777_2065797_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.6e-67	43.7
WP_095859570.1\|2065790_2067317_-	anthranilate synthase component I	A0A0B5J984	Pandoravirus	3.7e-36	40.4
WP_095859571.1\|2067542_2067929_-	chorismate mutase	NA	NA	NA	NA
WP_033014002.1\|2067925_2069026_-	3-dehydroquinate synthase	E5ERI4	Ostreococcus_lucimarinus_virus	8.3e-22	32.5
WP_033014001.1\|2069028_2070195_-	chorismate synthase	A0A291AU41	Pandoravirus	1.2e-42	36.5
WP_049624819.1\|2070294_2071065_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_033013999.1\|2071137_2071587_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	5.4e-28	46.2
WP_033009740.1\|2071685_2072648_-	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	7.2e-06	23.1
WP_033009739.1\|2072663_2073368_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_095859572.1\|2073372_2074203_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_033013997.1\|2074505_2074730_-	trp RNA-binding attenuation protein MtrB	NA	NA	NA	NA
WP_033013996.1\|2074743_2075310_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	1.5e-48	55.6
WP_008879623.1\|2075442_2075715_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	3.5e-30	78.9

DBSCAN-SWA_11

2130101 : 2140284

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095859592.1\|2130101_2131247_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.6e-23	34.9
WP_095859593.1\|2131806_2133063_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	7.7e-40	44.1
WP_095859595.1\|2133419_2133821_-	hypothetical protein	NA	NA	NA	NA
WP_033008290.1\|2133867_2134482_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.5e-14	34.7
WP_033008270.1\|2134808_2135570_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	9.4e-09	25.9
WP_033008269.1\|2135813_2136326_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_033008266.1\|2136377_2136728_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_033008265.1\|2136839_2137304_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.2e-42	60.1
WP_050367490.1\|2137323_2138517_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.4e-117	54.3
WP_033008263.1\|2138539_2139184_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.7e-39	44.6
WP_095859596.1\|2139186_2140284_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	7.9e-57	37.9

DBSCAN-SWA_12

2421667 : 2482171

Pacmanvirus(14.29%)

protease,coat,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095859721.1\|2421667_2423326_-\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_049624749.1\|2423484_2424588_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_055357870.1\|2424603_2425434_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_095859722.1\|2425462_2427013_-	L-aspartate oxidase	NA	NA	NA	NA
WP_047819372.1\|2427117_2428263_+	aminotransferase class V-fold PLP-dependent enzyme	A0A1X6WFP1	Pacmanvirus	5.6e-29	28.6
WP_094239027.1\|2428259_2428799_+	transcription repressor NadR	NA	NA	NA	NA
WP_033010956.1\|2428867_2429716_-	prephenate dehydratase	NA	NA	NA	NA
WP_033010955.1\|2429737_2430181_-	ACT domain-containing protein	NA	NA	NA	NA
WP_033014266.1\|2430199_2431501_-	GTPase ObgE	NA	NA	NA	NA
WP_095859723.1\|2431595_2432156_-	sporulation protein	NA	NA	NA	NA
WP_008881065.1\|2432334_2432625_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_033010951.1\|2432640_2432973_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_033010949.1\|2432974_2433283_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_095859724.1\|2433523_2434384_-	stage IV sporulation protein FB	NA	NA	NA	NA
WP_095859725.1\|2434376_2435144_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_095859726.1\|2435397_2436201_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_033010588.1\|2436203_2436896_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_049624755.1\|2436936_2437455_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_033010591.1\|2437451_2438318_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_033014277.1\|2438338_2439361_-	rod shape-determining protein	NA	NA	NA	NA
WP_055357875.1\|2439521_2440202_-	JAB domain-containing protein	NA	NA	NA	NA
WP_095859727.1\|2440341_2440929_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_095860243.1\|2441039_2442155_-	stage II sporulation protein D	NA	NA	NA	NA
WP_094239031.1\|2442271_2442733_-	type II secretion system protein	NA	NA	NA	NA
WP_095859728.1\|2442754_2443474_-	pilus assembly protein PilO	NA	NA	NA	NA
WP_013144607.1\|2443470_2444046_-	fimbrial protein	NA	NA	NA	NA
WP_082825830.1\|2444035_2444974_-	pilus assembly protein PilM	NA	NA	NA	NA
WP_095859729.1\|2445763_2446225_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_014195799.1\|2446468_2447716_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	4.9e-63	36.9
WP_095859730.1\|2447780_2448992_-	type II secretion system F family protein	NA	NA	NA	NA
WP_095859731.1\|2448978_2450034_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_015375512.1\|2450046_2451711_-	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_095859732.1\|2451707_2453078_-	hypothetical protein	NA	NA	NA	NA
WP_053532384.1\|2453094_2453874_-	photosystem reaction center subunit H	NA	NA	NA	NA
WP_095859733.1\|2453863_2455480_-	hypothetical protein	NA	NA	NA	NA
WP_095859734.1\|2455623_2456244_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_044744827.1\|2456227_2456806_+	hypothetical protein	NA	NA	NA	NA
WP_095859735.1\|2456849_2458556_+	hypothetical protein	NA	NA	NA	NA
WP_095859736.1\|2458650_2461881_-	VWA domain-containing protein	A0A140XG62	Salmonella_phage	3.9e-11	29.0
WP_095859737.1\|2461949_2463245_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_095859738.1\|2463462_2466105_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	2.5e-165	42.5
WP_011232115.1\|2466581_2466770_+	hypothetical protein	NA	NA	NA	NA
WP_095859739.1\|2466808_2467840_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_050367623.1\|2467882_2468932_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_063211600.1\|2469050_2470340_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_095859740.1\|2470356_2471331_-	porphobilinogen synthase	NA	NA	NA	NA
WP_050367625.1\|2471331_2472099_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_095859741.1\|2472095_2473028_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_095859742.1\|2473043_2473862_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_095859743.1\|2473872_2475237_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_033014324.1\|2475404_2475890_+	hypothetical protein	NA	NA	NA	NA
WP_033014325.1\|2475931_2476519_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_095859744.1\|2476515_2478858_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.4e-175	43.8
WP_050367631.1\|2479088_2480762_-\|protease	ATP-dependent protease LonB	A0A076FMQ5	Aureococcus_anophage	1.8e-12	32.2
WP_044744796.1\|2480905_2482171_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	8.3e-151	67.0

DBSCAN-SWA_13

2660541 : 2712859

Staphylococcus_phage(64.29%)

holin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033009793.1\|2660541_2661189_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_050367707.1\|2661328_2661598_+	hypothetical protein	NA	NA	NA	NA
WP_033009796.1\|2661649_2662435_-	phosphotransferase family protein	NA	NA	NA	NA
WP_063210942.1\|2663035_2663971_-	hypothetical protein	NA	NA	NA	NA
WP_049626118.1\|2663975_2664554_-	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_049625020.1\|2664550_2665735_-	MFS transporter	NA	NA	NA	NA
WP_095859803.1\|2665803_2667219_-	dipeptidase PepV	NA	NA	NA	NA
WP_008880936.1\|2667469_2667691_+	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_033009804.1\|2667786_2668533_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_033006856.1\|2668637_2668850_+	hypothetical protein	NA	NA	NA	NA
WP_095859804.1\|2669066_2670692_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_094239107.1\|2670804_2672115_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	7.5e-30	58.9
WP_008880941.1\|2672317_2672497_-	sporulation protein Cse60	NA	NA	NA	NA
WP_095859806.1\|2672612_2674259_-	peptidase M4 family protein	NA	NA	NA	NA
WP_095859807.1\|2674800_2676075_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_050367712.1\|2676349_2676664_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	3.3e-16	47.9
WP_095859808.1\|2676903_2679321_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	74.5
WP_095859809.1\|2679681_2680881_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	8.0e-95	46.7
WP_033009817.1\|2680996_2681161_-	hypothetical protein	NA	NA	NA	NA
WP_033009819.1\|2681293_2681557_-	YtzC family protein	NA	NA	NA	NA
WP_063210932.1\|2682013_2682601_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	7.7e-43	47.3
WP_050368712.1\|2682658_2683741_-	tetraprenyl-beta-curcumene synthase family protein	NA	NA	NA	NA
WP_095859811.1\|2684106_2684655_+	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_095859812.1\|2684677_2685889_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-164	75.4
WP_095859813.1\|2686601_2688188_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	6.9e-195	63.8
WP_033018136.1\|2689422_2690670_+	MFS transporter	NA	NA	NA	NA
WP_063210924.1\|2690942_2691893_-\|transposase	transposase	NA	NA	NA	NA
WP_095859814.1\|2692126_2692369_-	DUF2584 domain-containing protein	NA	NA	NA	NA
WP_095859815.1\|2692437_2693226_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	8.8e-34	37.7
WP_095859816.1\|2693518_2694523_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_050367718.1\|2694541_2695333_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.6e-35	38.1
WP_033014564.1\|2695316_2696126_+	ABC transporter permease	NA	NA	NA	NA
WP_047818907.1\|2696241_2696709_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	2.7e-22	39.0
WP_094239126.1\|2696767_2697100_-	hydrolase	NA	NA	NA	NA
WP_095859817.1\|2697158_2697554_-\|holin	phage holin family protein	A0A0N7GFE6	Paenibacillus_phage	6.0e-23	46.6
WP_095859818.1\|2697707_2698148_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	6.2e-53	67.1
WP_095860248.1\|2700611_2701205_-	hypothetical protein	NA	NA	NA	NA
WP_095859819.1\|2701367_2703020_-	hypothetical protein	NA	NA	NA	NA
WP_003253480.1\|2704530_2705247_-	hypothetical protein	NA	NA	NA	NA
WP_095860249.1\|2705926_2706856_+\|transposase	ISL3 family transposase	A0A0A8WEF4	Clostridium_phage	8.8e-17	22.9
WP_094238572.1\|2707000_2707801_-	AAA family ATPase	NA	NA	NA	NA
WP_095858787.1\|2708217_2708763_+\|transposase	transposase	NA	NA	NA	NA
WP_015864903.1\|2708915_2710169_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6
WP_015864165.1\|2710161_2710962_+	AAA family ATPase	NA	NA	NA	NA
WP_095859417.1\|2712295_2712859_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_14

2744056 : 2774583

Geobacillus_phage(57.14%)

transposase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015864904.1\|2744056_2745244_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_099233601.1\|2746195_2746675_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_095859832.1\|2747105_2748473_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_095859833.1\|2749173_2749458_+	hypothetical protein	NA	NA	NA	NA
WP_095859834.1\|2749423_2750101_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_158522917.1\|2750427_2751213_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_095859836.1\|2751415_2752216_-	AAA family ATPase	NA	NA	NA	NA
WP_033011707.1\|2752208_2753462_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	1.2e-11	26.3
WP_095859837.1\|2753614_2754160_-\|transposase	transposase	NA	NA	NA	NA
WP_095859838.1\|2754368_2755556_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_019417960.1\|2756860_2757166_-	hypothetical protein	NA	NA	NA	NA
WP_095859839.1\|2757171_2758452_-	peptidoglycan-binding protein	A0A2P1JUA1	Erwinia_phage	2.5e-06	37.6
WP_095859840.1\|2758578_2758827_-	DNA-binding protein	A0A290FZJ4	Caldibacillus_phage	6.2e-18	57.3
WP_145956586.1\|2758840_2759203_-	hypothetical protein	NA	NA	NA	NA
WP_013144115.1\|2759341_2759902_-	hypothetical protein	NA	NA	NA	NA
WP_013144114.1\|2759908_2760679_-	hypothetical protein	W8ECW5	Geobacillus_phage	1.3e-05	30.6
WP_095859841.1\|2760745_2761462_-	N-acetylmuramoyl-L-alanine amidase	Q0H257	Geobacillus_phage	1.2e-58	55.7
WP_095859842.1\|2761514_2762333_-	hypothetical protein	NA	NA	NA	NA
WP_095859843.1\|2762593_2762953_-	hypothetical protein	NA	NA	NA	NA
WP_095859844.1\|2762973_2763168_-	hypothetical protein	NA	NA	NA	NA
WP_033020079.1\|2763167_2763518_-	hypothetical protein	NA	NA	NA	NA
WP_095859845.1\|2763532_2766424_-	glycoside hydrolase	W8EK73	Geobacillus_phage	8.0e-234	43.8
WP_095859846.1\|2766420_2767218_-	hypothetical protein	W8EBC9	Geobacillus_phage	9.1e-55	45.2
WP_095859847.1\|2767222_2767420_-	hypothetical protein	W8ECV6	Geobacillus_phage	7.5e-11	56.5
WP_095859848.1\|2767416_2768910_-	hypothetical protein	W8EEW0	Geobacillus_phage	2.4e-141	51.4
WP_095859849.1\|2768920_2769985_-	hypothetical protein	W8EIX3	Geobacillus_phage	2.2e-48	37.5
WP_095859850.1\|2770000_2770750_-\|tail	phage tail protein	W8EK66	Geobacillus_phage	2.1e-53	40.4
WP_095859851.1\|2770746_2772309_-	hypothetical protein	A0A2H4JC82	uncultured_Caudovirales_phage	3.8e-20	46.3
WP_080986158.1\|2772556_2773339_-	endonuclease	A0A1B1P765	Bacillus_phage	3.3e-89	59.8
WP_095859852.1\|2773449_2774583_-	tape measure protein	A6XMK6	Bacillus_virus	1.0e-99	70.5

DBSCAN-SWA_15

2778127 : 2832814

Bacillus_virus(19.23%)

integrase,portal,terminase,capsid,transposase,head

attL 2779202:2779217|attR 2837690:2837705

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095859857.1\|2778127_2779045_-\|capsid	phage major capsid protein	V9QJI4	Rhizobium_phage	2.2e-36	37.3
2779202:2779217	attL	NA	NA	NA	NA
WP_095859858.1\|2780549_2781416_-\|head	phage head morphogenesis protein	NA	NA	NA	NA
WP_095859859.1\|2781408_2782851_-\|portal	phage portal protein	A0A2L1IVM1	Streptomyces_phage	1.0e-48	31.4
WP_095859860.1\|2782869_2784288_-\|terminase	phage terminase large subunit	A0A2K9V3I6	Faecalibacterium_phage	3.3e-140	54.5
WP_095859861.1\|2784262_2784730_-	hypothetical protein	NA	NA	NA	NA
WP_013144090.1\|2785018_2785381_-	DUF2513 domain-containing protein	A0A2H4J4K9	uncultured_Caudovirales_phage	7.2e-07	28.7
WP_095859863.1\|2786118_2786868_-	DUF4065 domain-containing protein	Q0H268	Geobacillus_phage	7.8e-141	98.8
WP_015864904.1\|2787438_2788626_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_095859864.1\|2789338_2789524_-	hypothetical protein	S6AVV9	Thermus_phage	1.6e-07	51.7
WP_095859865.1\|2789520_2789937_-	transcriptional regulator	E5DV97	Deep-sea_thermophilic_phage	4.8e-39	57.9
WP_095859866.1\|2789933_2790437_-	hypothetical protein	A0A0C5AJE6	Paenibacillus_phage	1.1e-32	51.7
WP_095859867.1\|2790446_2790995_-	dUTPase	S6AVW3	Thermus_phage	6.7e-33	47.6
WP_095859868.1\|2791013_2791196_-	hypothetical protein	NA	NA	NA	NA
WP_095859869.1\|2791659_2792157_-	single-stranded DNA-binding protein	E5DV85	Deep-sea_thermophilic_phage	1.1e-45	58.8
WP_095859870.1\|2792538_2792967_-	hypothetical protein	NA	NA	NA	NA
WP_095859871.1\|2792971_2794222_-	DNA helicase	A0A0U4B0A1	Bacillus_phage	8.3e-79	38.1
WP_095859872.1\|2794218_2794482_-	hypothetical protein	NA	NA	NA	NA
WP_095859873.1\|2795265_2795493_-	hypothetical protein	E5DV81	Deep-sea_thermophilic_phage	3.4e-15	56.7
WP_095859874.1\|2795664_2796366_-	single-stranded DNA-binding protein	A0A1J0MFT8	Staphylococcus_phage	1.1e-38	44.4
WP_011888089.1\|2796861_2797056_-	hypothetical protein	A6M980	Geobacillus_virus	3.2e-22	73.3
WP_095859875.1\|2797056_2797236_-	hypothetical protein	Q0H238	Geobacillus_phage	1.0e-06	89.7
WP_095860254.1\|2797207_2797456_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_095859876.1\|2797493_2798066_-	phage antirepressor Ant	A6XMM0	Bacillus_virus	5.3e-105	98.9
WP_095859877.1\|2798037_2798229_-	hypothetical protein	A6XMM0	Bacillus_virus	7.5e-24	100.0
WP_015985936.1\|2798243_2798480_-	helix-turn-helix transcriptional regulator	B3RH39	Bacillus_virus	7.4e-37	100.0
WP_095859878.1\|2798623_2799094_+	helix-turn-helix transcriptional regulator	A6XML9	Bacillus_virus	4.8e-80	99.4
WP_095859879.1\|2799114_2799555_+	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	1.7e-74	96.5
WP_095859880.1\|2799597_2800731_+\|integrase	site-specific integrase	A8ATX2	Listeria_phage	6.6e-99	48.7
WP_095859881.1\|2808724_2809633_-	DMT family transporter	NA	NA	NA	NA
WP_033010733.1\|2809694_2810372_+	MgtC/SapB family protein	G3MA03	Bacillus_virus	1.0e-14	34.5
WP_095859882.1\|2810322_2812095_-	recombinase family protein	E5DV73	Deep-sea_thermophilic_phage	4.6e-30	25.9
WP_061567183.1\|2812177_2812387_-	hypothetical protein	NA	NA	NA	NA
WP_061567182.1\|2812722_2813310_-	hypothetical protein	NA	NA	NA	NA
WP_061567181.1\|2813516_2814251_-	hypothetical protein	NA	NA	NA	NA
WP_095859883.1\|2814368_2815055_-	hypothetical protein	NA	NA	NA	NA
WP_061567322.1\|2815437_2816064_+	hypothetical protein	NA	NA	NA	NA
WP_095858787.1\|2817054_2817600_+\|transposase	transposase	NA	NA	NA	NA
WP_015864903.1\|2817752_2819006_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6
WP_015864165.1\|2818998_2819799_+	AAA family ATPase	NA	NA	NA	NA
WP_061567323.1\|2820216_2820702_-	hypothetical protein	NA	NA	NA	NA
WP_145956588.1\|2820713_2821043_-	hypothetical protein	NA	NA	NA	NA
WP_033026122.1\|2821336_2821942_-	recombinase family protein	M9Q1K0	Clostridium_phage	1.0e-18	33.0
WP_061567325.1\|2822255_2823095_-	hypothetical protein	NA	NA	NA	NA
WP_095859884.1\|2823229_2824234_-	hypothetical protein	NA	NA	NA	NA
WP_145956589.1\|2824485_2826708_-	hypothetical protein	NA	NA	NA	NA
WP_033011705.1\|2826860_2827406_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_095859886.1\|2827558_2828812_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	1.3e-10	26.0
WP_064213564.1\|2828804_2829605_+	AAA family ATPase	NA	NA	NA	NA
WP_095859887.1\|2829802_2831149_-	leucine-rich repeat protein	NA	NA	NA	NA
WP_033845283.1\|2831365_2832814_+\|transposase	IS66-like element ISBst12 family transposase	NA	NA	NA	NA
2837690:2837705	attR	NA	NA	NA	NA

DBSCAN-SWA_16

2839480 : 2894840

Bacillus_phage(22.22%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061567192.1\|2839480_2840362_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.7e-49	42.8
WP_061567191.1\|2840370_2840667_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_064213516.1\|2840755_2841235_-	gamma-glutamylcyclotransferase	G3MAQ5	Bacillus_virus	2.0e-09	33.6
WP_061567522.1\|2841343_2842300_-	hypothetical protein	A0A2K9V489	Faecalibacterium_phage	6.9e-41	35.7
WP_095859891.1\|2842901_2843570_-	hypothetical protein	NA	NA	NA	NA
WP_033026134.1\|2843586_2844309_-	hypothetical protein	NA	NA	NA	NA
WP_095859892.1\|2844308_2845070_-	hypothetical protein	NA	NA	NA	NA
WP_033026138.1\|2846254_2846524_-	hypothetical protein	NA	NA	NA	NA
WP_095859893.1\|2846847_2847600_-	hypothetical protein	NA	NA	NA	NA
WP_095859894.1\|2847629_2848289_-	hypothetical protein	NA	NA	NA	NA
WP_042382392.1\|2848308_2848839_-	recombinase family protein	NA	NA	NA	NA
WP_095859895.1\|2849620_2849902_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	8.0e-14	65.1
WP_095859896.1\|2850422_2851358_-	hypothetical protein	NA	NA	NA	NA
WP_095859897.1\|2851371_2852139_-	hypothetical protein	NA	NA	NA	NA
WP_089113833.1\|2853054_2853372_-	hypothetical protein	NA	NA	NA	NA
WP_095859898.1\|2853601_2855674_-	hypothetical protein	NA	NA	NA	NA
WP_013877640.1\|2855663_2856722_-\|transposase	IS630 family transposase	A0A1V0SDF8	Indivirus	1.3e-11	26.5
WP_145956590.1\|2856795_2859984_-	hypothetical protein	NA	NA	NA	NA
WP_145956591.1\|2860180_2860717_-	hypothetical protein	NA	NA	NA	NA
WP_020279908.1\|2861133_2861934_-	AAA family ATPase	NA	NA	NA	NA
WP_033011561.1\|2861926_2863177_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	9.7e-11	26.3
WP_033011559.1\|2863318_2863882_-	hypothetical protein	NA	NA	NA	NA
WP_095859901.1\|2863853_2864777_-	copper amine oxidase N-terminal domain-containing protein	NA	NA	NA	NA
WP_064213433.1\|2865290_2865902_-	lecithin retinol acyltransferase family protein	NA	NA	NA	NA
WP_095859902.1\|2866483_2867392_+	nuclease	O64020	Bacillus_phage	1.2e-15	44.3
WP_033016279.1\|2867515_2867767_-	hypothetical protein	NA	NA	NA	NA
WP_033010730.1\|2867823_2868324_-	N-acetyltransferase	NA	NA	NA	NA
WP_145956592.1\|2869032_2869446_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_095859903.1\|2870199_2871858_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_095859904.1\|2871889_2872831_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_094240049.1\|2873185_2873920_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_011231214.1\|2874124_2875003_+\|transposase	IS982-like element ISGsp1 family transposase	NA	NA	NA	NA
WP_033016280.1\|2875314_2875503_-	H-type small acid-soluble spore protein	NA	NA	NA	NA
WP_095859905.1\|2875615_2876611_+	potassium channel family protein	A0A1B0Y2S3	Lactobacillus_phage	1.2e-06	43.1
WP_033010726.1\|2876607_2877012_-	hypothetical protein	NA	NA	NA	NA
WP_033016353.1\|2877257_2878607_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_094239149.1\|2879271_2880435_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_033010722.1\|2880581_2880815_+	DUF378 domain-containing protein	NA	NA	NA	NA
WP_033010720.1\|2880877_2881237_-	general stress protein 13	NA	NA	NA	NA
WP_033010718.1\|2881586_2882759_-	aminotransferase	NA	NA	NA	NA
WP_033010737.1\|2882755_2883256_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_033010717.1\|2883306_2883570_-	DUF1871 family protein	NA	NA	NA	NA
WP_095859906.1\|2883653_2884868_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_095859907.1\|2885113_2885638_-	superoxide dismutase family protein	NA	NA	NA	NA
WP_033010715.1\|2885694_2885910_-	hypothetical protein	NA	NA	NA	NA
WP_033016292.1\|2885979_2886600_-	3'-5' exonuclease KapD	NA	NA	NA	NA
WP_033016293.1\|2886767_2887136_-	Na+/H+ antiporter subunit G	NA	NA	NA	NA
WP_033010711.1\|2887113_2887395_-	Na(+)/H(+) antiporter subunit F1	NA	NA	NA	NA
WP_095859908.1\|2887391_2887868_-	Na+/H+ antiporter subunit E	NA	NA	NA	NA
WP_095859909.1\|2887874_2889347_-	Na+/H+ antiporter subunit D	NA	NA	NA	NA
WP_095859910.1\|2889339_2889681_-	Na(+)/H(+) antiporter subunit C	NA	NA	NA	NA
WP_095859911.1\|2889681_2890098_-	Na(+)/H(+) antiporter subunit B	NA	NA	NA	NA
WP_033017188.1\|2893655_2894840_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3V0V2	Geobacillus_virus	1.8e-75	41.4

DBSCAN-SWA_17

3010018 : 3081677

Pseudomonas_phage(13.33%)

protease,holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095859955.1\|3010018_3010381_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_011232554.1\|3010483_3010810_-	DUF4870 domain-containing protein	A0A2H4JDX0	uncultured_Caudovirales_phage	2.1e-05	31.1
WP_095860261.1\|3010937_3013796_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	58.1
WP_095859956.1\|3013812_3015789_-	excinuclease ABC subunit UvrB	B2CRJ8	Acidianus_filamentous_virus	6.1e-07	36.6
WP_033012047.1\|3015964_3016186_-	CsbA family protein	NA	NA	NA	NA
WP_050367797.1\|3016200_3017373_-	PDZ domain-containing protein	NA	NA	NA	NA
WP_033012045.1\|3017593_3018136_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_095859957.1\|3018260_3019703_-	PDZ domain-containing protein	A0A0R6PIZ1	Moraxella_phage	9.8e-23	32.2
WP_095859958.1\|3020068_3020782_-	pirin family protein	NA	NA	NA	NA
WP_021321653.1\|3022653_3023445_-	malonyl-ACP O-methyltransferase BioC	NA	NA	NA	NA
WP_014196746.1\|3023437_3024130_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_095859959.1\|3024505_3025804_-	peptidoglycan DD-metalloendopeptidase family protein	A0A7K9	Microcystis_virus	1.8e-15	40.0
WP_095859960.1\|3025828_3026722_-	ABC transporter permease	NA	NA	NA	NA
WP_095860262.1\|3026702_3027398_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	4.1e-27	36.8
WP_053532702.1\|3027616_3027949_-	cytochrome c	NA	NA	NA	NA
WP_095859961.1\|3028011_3028875_-	YitT family protein	NA	NA	NA	NA
WP_145956593.1\|3028993_3030098_-	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	2.4e-05	39.0
WP_095859962.1\|3030189_3032703_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_095859963.1\|3032947_3033484_-	hypothetical protein	NA	NA	NA	NA
WP_047819006.1\|3033569_3034118_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_095859964.1\|3034292_3035372_+	HD-GYP domain-containing protein	NA	NA	NA	NA
WP_095859965.1\|3035405_3035756_-	flagellar protein FliT	NA	NA	NA	NA
WP_015375824.1\|3035755_3036157_-	flagellar export chaperone FliS	NA	NA	NA	NA
WP_095859966.1\|3036359_3037862_-	flagellar hook-associated protein 2	NA	NA	NA	NA
WP_095859967.1\|3037877_3038237_-	flagellar protein FlaG	NA	NA	NA	NA
WP_033014989.1\|3038526_3038913_-	hypothetical protein	NA	NA	NA	NA
WP_033026284.1\|3038909_3039170_-	hypothetical protein	NA	NA	NA	NA
WP_095859968.1\|3039327_3040986_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_095858915.1\|3041467_3042604_+\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	2.1e-36	28.9
WP_095859970.1\|3043691_3043886_-	hypothetical protein	NA	NA	NA	NA
WP_095859971.1\|3044152_3045178_-	flagellin	NA	NA	NA	NA
WP_095859972.1\|3045366_3045606_-	carbon storage regulator CsrA	H2BD56	Pseudomonas_phage	2.5e-08	56.9
WP_095859973.1\|3045622_3046057_-	flagellar assembly protein FliW	NA	NA	NA	NA
WP_095859974.1\|3046079_3046634_-	hypothetical protein	NA	NA	NA	NA
WP_033009483.1\|3046668_3047562_-	flagellar hook-associated protein FlgL	NA	NA	NA	NA
WP_095859975.1\|3047572_3049168_-	flagellar hook-associated protein FlgK	NA	NA	NA	NA
WP_063210692.1\|3049180_3049648_-	flagellar protein FlgN	NA	NA	NA	NA
WP_095859976.1\|3049663_3049930_-	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
WP_095859977.1\|3050001_3050412_-	hypothetical protein	NA	NA	NA	NA
WP_063329626.1\|3050647_3051085_-	YaaR family protein	NA	NA	NA	NA
WP_095859978.1\|3051167_3053561_-	flagellar protein	NA	NA	NA	NA
WP_095860264.1\|3053582_3054005_-	flagellar export chaperone FliS	NA	NA	NA	NA
WP_095859979.1\|3054061_3054358_-	flagellar biosynthesis protein FlhS	NA	NA	NA	NA
WP_095859980.1\|3054354_3056511_-	hypothetical protein	NA	NA	NA	NA
WP_064213564.1\|3056719_3057520_-	AAA family ATPase	NA	NA	NA	NA
WP_095859148.1\|3057512_3058763_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	9.7e-11	26.8
WP_095859149.1\|3058904_3059468_-\|transposase	transposase	NA	NA	NA	NA
WP_095859981.1\|3059614_3066442_-	hypothetical protein	NA	NA	NA	NA
WP_095859982.1\|3066514_3067207_-	ComF family protein	NA	NA	NA	NA
WP_095859983.1\|3067203_3068595_-	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	3.8e-64	38.4
WP_155266788.1\|3068594_3068768_+	hypothetical protein	NA	NA	NA	NA
WP_033009498.1\|3069316_3070162_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	2.4e-13	34.6
WP_095859985.1\|3070405_3071080_-	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	9.6e-05	31.0
WP_095859986.1\|3071076_3072258_-	histidine kinase	NA	NA	NA	NA
WP_095859987.1\|3072474_3073119_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	9.1e-37	39.3
WP_095859988.1\|3075884_3076763_-	accessory Sec system S-layer assembly protein	NA	NA	NA	NA
WP_095859989.1\|3076779_3079143_-	accessory Sec system translocase SecA2	NA	NA	NA	NA
WP_095859990.1\|3079439_3081677_-\|protease	trypsin-like serine protease	W5SAB9	Pithovirus	4.0e-07	31.1

DBSCAN-SWA_18

3211096 : 3247130

Rhodobacter_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095860062.1\|3211096_3211990_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_095860063.1\|3212777_3213251_+	hypothetical protein	NA	NA	NA	NA
WP_053532361.1\|3213293_3213494_-	hypothetical protein	NA	NA	NA	NA
WP_095860064.1\|3213734_3214232_+	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_095860065.1\|3214403_3215342_+	transcriptional regulator	NA	NA	NA	NA
WP_013524778.1\|3215489_3215948_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_095860066.1\|3215961_3216567_+	DUF4411 family protein	NA	NA	NA	NA
WP_044744270.1\|3216937_3217327_-	hypothetical protein	NA	NA	NA	NA
WP_095860067.1\|3217339_3218260_-	ADP-ribosyl-[dinitrogen reductase] hydrolase	G3M9X5	Bacillus_virus	1.0e-78	50.0
WP_145956595.1\|3218359_3219106_-	hypothetical protein	NA	NA	NA	NA
WP_095860069.1\|3219564_3220017_+	N-acetyltransferase	NA	NA	NA	NA
WP_095860070.1\|3222132_3222879_-	hypothetical protein	NA	NA	NA	NA
WP_095860071.1\|3222880_3223753_-	hypothetical protein	NA	NA	NA	NA
WP_064213564.1\|3224847_3225648_-	AAA family ATPase	NA	NA	NA	NA
WP_095859148.1\|3225640_3226891_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	9.7e-11	26.8
WP_095859149.1\|3227032_3227596_-\|transposase	transposase	NA	NA	NA	NA
WP_095860072.1\|3229502_3230690_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_095860073.1\|3231035_3232307_-	hypothetical protein	NA	NA	NA	NA
WP_095860074.1\|3232401_3234069_-	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_095860075.1\|3234094_3235873_-	Hsp70 family protein	A0A1V0SBC3	Catovirus	1.9e-31	27.1
WP_095860076.1\|3235893_3237339_-	hypothetical protein	NA	NA	NA	NA
WP_095860077.1\|3237320_3239741_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_095860078.1\|3240102_3241437_-	MFS transporter	NA	NA	NA	NA
WP_095860080.1\|3241996_3242917_-	DMT family transporter	NA	NA	NA	NA
WP_011888351.1\|3244161_3244419_-	DUF2283 domain-containing protein	NA	NA	NA	NA
WP_095860275.1\|3244387_3244792_-	hypothetical protein	NA	NA	NA	NA
WP_095858787.1\|3245178_3245724_+\|transposase	transposase	NA	NA	NA	NA
WP_015864903.1\|3245876_3247130_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	4.8e-10	25.6

DBSCAN-SWA_19

3339787 : 3431984

Wolbachia_phage(21.05%)

integrase,protease,coat,transposase,tRNA

attL 3394299:3394358|attR 3427312:3428680

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095860128.1\|3339787_3341461_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_033010742.1\|3341465_3341897_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_095860129.1\|3342150_3342528_-	cytochrome-c oxidase	NA	NA	NA	NA
WP_049624641.1\|3342659_3343535_-	agmatinase	NA	NA	NA	NA
WP_095860130.1\|3343547_3344375_-	polyamine aminopropyltransferase	NA	NA	NA	NA
WP_095860131.1\|3344631_3346677_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_011232874.1\|3346808_3347324_-	hypothetical protein	NA	NA	NA	NA
WP_011232875.1\|3347341_3348010_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011232876.1\|3348142_3348331_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_014196148.1\|3348439_3349699_-	HNH endonuclease	Q331Y3	Clostridium_botulinum_C_phage	1.1e-75	45.3
WP_033015432.1\|3349947_3350466_-	hypothetical protein	NA	NA	NA	NA
WP_095860278.1\|3350479_3351778_-	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	3.6e-24	28.6
WP_011232879.1\|3351922_3352150_-	DUF1450 domain-containing protein	NA	NA	NA	NA
WP_011232880.1\|3352325_3352979_+	RsfA family transcriptional regulator	A0A1D6X8E5	Bacillus_phage	9.9e-07	51.5
WP_095860132.1\|3353117_3353969_-	lipoate--protein ligase family protein	NA	NA	NA	NA
WP_095860133.1\|3354168_3355149_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_021321327.1\|3355406_3356153_+	heme-dependent peroxidase	NA	NA	NA	NA
WP_011232884.1\|3356358_3356805_+	cell wall hydrolase	NA	NA	NA	NA
WP_095860134.1\|3356823_3357408_+\|coat	spore coat protein GerQ	NA	NA	NA	NA
WP_095860135.1\|3357603_3357975_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_095860136.1\|3358045_3359305_-	HNH endonuclease	Q331Y3	Clostridium_botulinum_C_phage	1.5e-75	45.3
WP_063167150.1\|3359769_3360069_-	YwdI family protein	NA	NA	NA	NA
WP_011232888.1\|3360086_3360776_-	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	2.7e-55	50.2
WP_145956597.1\|3364696_3364930_-	hypothetical protein	NA	NA	NA	NA
WP_095860137.1\|3365041_3366226_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3V0V2	Geobacillus_virus	4.1e-75	41.1
WP_095860138.1\|3366446_3367829_-\|tRNA	glycine--tRNA ligase	A0A1V0SAN4	Catovirus	2.5e-52	30.2
WP_095860279.1\|3368116_3368947_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_095860139.1\|3369026_3370223_-	MFS transporter	NA	NA	NA	NA
WP_145956598.1\|3370331_3370736_+	hypothetical protein	NA	NA	NA	NA
WP_013146668.1\|3370810_3371128_+	hypothetical protein	NA	NA	NA	NA
WP_033011559.1\|3371807_3372371_+	hypothetical protein	NA	NA	NA	NA
WP_033011561.1\|3372512_3373763_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	9.7e-11	26.3
WP_020279908.1\|3373755_3374556_+	AAA family ATPase	NA	NA	NA	NA
WP_094239823.1\|3376208_3377327_+	ABC transporter permease	NA	NA	NA	NA
WP_094239822.1\|3377340_3378639_+	ABC transporter permease	NA	NA	NA	NA
WP_062679206.1\|3378641_3379331_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-29	35.3
WP_094239821.1\|3379327_3379738_+	hypothetical protein	NA	NA	NA	NA
WP_095858915.1\|3382908_3384045_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	2.1e-36	28.9
WP_095860142.1\|3384462_3385599_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	7.2e-37	29.1
WP_095858915.1\|3386016_3387153_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	2.1e-36	28.9
WP_095860143.1\|3387722_3388859_-\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	1.2e-36	28.9
WP_095860144.1\|3389505_3391263_+	hypothetical protein	NA	NA	NA	NA
WP_011232902.1\|3391279_3392140_+	phosphate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_095860145.1\|3392213_3393149_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_021321312.1\|3393145_3394039_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
3394299:3394358	attL	NA	NA	NA	NA
WP_095859838.1\|3394360_3395548_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_110107477.1\|3395677_3395845_-	HTH domain-containing protein	NA	NA	NA	NA
WP_095860146.1\|3395863_3396358_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_095860147.1\|3396383_3396758_-	hypothetical protein	NA	NA	NA	NA
WP_095860148.1\|3396848_3398084_+	PucR family transcriptional regulator	NA	NA	NA	NA
WP_011232912.1\|3398201_3399335_+	alanine dehydrogenase	NA	NA	NA	NA
WP_095860149.1\|3400277_3400796_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_095860150.1\|3400841_3401657_+	pyridoxine/pyridoxal/pyridoxamine kinase	NA	NA	NA	NA
WP_095860151.1\|3401811_3402672_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_033009164.1\|3403686_3404409_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.1e-33	40.5
WP_011232920.1\|3404596_3404896_-	cytochrome aa3 quinol oxidase subunit IV	NA	NA	NA	NA
WP_015376112.1\|3404897_3405512_-	cytochrome aa3 quinol oxidase subunit III	NA	NA	NA	NA
WP_095860152.1\|3405515_3407462_-	cytochrome aa3 quinol oxidase subunit I	NA	NA	NA	NA
WP_042381220.1\|3407479_3408385_-	cytochrome aa3 quinol oxidase subunit II	NA	NA	NA	NA
WP_033008879.1\|3408886_3409597_-	RNA methyltransferase	NA	NA	NA	NA
WP_095860153.1\|3410258_3411425_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_050368156.1\|3411823_3412354_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_095860281.1\|3412353_3412656_+\|transposase	transposase	NA	NA	NA	NA
WP_095860280.1\|3412692_3412881_+\|integrase	integrase	NA	NA	NA	NA
WP_158522922.1\|3412929_3414369_-	hypothetical protein	NA	NA	NA	NA
WP_033845283.1\|3414382_3415831_+\|transposase	IS66-like element ISBst12 family transposase	NA	NA	NA	NA
WP_095860155.1\|3416306_3416861_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_095860156.1\|3417007_3418141_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_060788907.1\|3418221_3418575_-	S8 family serine peptidase	A0A217EQY2	Bacillus_phage	2.0e-22	55.6
WP_095860157.1\|3419064_3420453_-	transcriptional regulator	NA	NA	NA	NA
WP_095860158.1\|3420638_3422165_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_033008876.1\|3422356_3423319_+	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_050368738.1\|3423482_3424607_-	glycerate kinase	W6LM47	Streptococcus_phage	9.9e-55	43.9
WP_033017188.1\|3424796_3425981_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3V0V2	Geobacillus_virus	1.8e-75	41.4
WP_095859838.1\|3426121_3427309_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_013877640.1\|3427620_3428679_+\|transposase	IS630 family transposase	A0A1V0SDF8	Indivirus	1.3e-11	26.5
WP_020279908.1\|3429940_3430741_-	AAA family ATPase	NA	NA	NA	NA
3427312:3428680	attR	NA	NA	NA	NA
WP_033011561.1\|3430733_3431984_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	9.7e-11	26.3

DBSCAN-SWA_20

3436618 : 3446491

uncultured_Mediterranean_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050368739.1\|3436618_3437836_-	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	8.0e-18	28.8
WP_063211306.1\|3437937_3438732_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.5e-44	36.5
WP_095860160.1\|3438738_3439524_-	transcriptional regulator	NA	NA	NA	NA
WP_095860161.1\|3439510_3440839_-	transcriptional regulator	NA	NA	NA	NA
WP_033008868.1\|3440831_3442661_-	cell wall metabolism sensor histidine kinase WalK	A0A1V0SGX0	Hokovirus	9.5e-23	27.0
WP_095860162.1\|3442667_3443381_-	response regulator transcription factor	W8CYM9	Bacillus_phage	7.7e-45	41.9
WP_095860282.1\|3443686_3444973_-	adenylosuccinate synthase	L7Y4J5	Megavirus	7.8e-72	36.2
WP_033008866.1\|3445126_3446491_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	3.2e-124	52.8

Anti-CRISPR protein detection

Acr_ID: NZ_CP016552.1|WP_095859976.1|3049663_3049930_-|flagellar-biosynthesis-anti-sigma-factor-FlgM

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP016552.1|WP_095859976.1|3049663_3049930_-|flagellar-biosynthesis-anti-sigma-factor-FlgM

3049663_3049930_-

88 aa aa

3010018-3081677

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP016552_9	Orphan	9.1\|3389140\|52\|NZ_CP016552\|CRISPRCasFinder	3389140-3389191	52	3043040-3042989	0

1. spacer 9.1|3389140|52|NZ_CP016552|CRISPRCasFinder matches to NZ_CP016552 position: 3043040-3042989, mismatch: 0

aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	CRISPR spacer
aaatcccgtcagccagcggtgattttcatccccgggtggagggcagatcgtg	Protospacer
****************************************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP016552

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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