CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022386	Capnocytophaga gingivalis strain H1496 chromosome, complete genome	8 crisprs	cas9,DEDDh,WYL,PD-DExK,cas3	1	6	0	0

1. NZ_CP022386

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022386_1

• CRISPR_ID: NZ_CP022386_1
• CRISPR_location: 174049-174163
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP022386_1

Consensus_repeat	Method
AGTTATGAGAAACTCTGAGAAGCTCAGGGCTTTCAGGGAAT	CRISPRCasFinder

spacers of NZ_CP022386_1

>1.1|174090|33|NZ_CP022386|CRISPRCasFinder
TTCTAATTGTTAATTATTTAATTATGACTCTTG

CRISPR arrays and Neighbor proteins around NZ_CP022386_1

CRISPR arrays

The CRISPR arrays of NZ_CP022386_1

>merge|NZ_CP022386|1|174049-174163|CRISPRCasFinder
AGTTATGAGAAACTCTGAGAAGCTCAGGGCTTTCAGGGAATTTCTAATTGTTAATTATTTAATTATGACTCTTGAGTTGTGAGAAACTCTGAGAAGCTCAGGGCTTTCAGGGAAT

>NZ_CP022386|1|1|174049-174163|CRISPRCasFinder
AGTTATGAGAAACTCTGAGAAGCTCAGGGCTTTCAGGGAAT	TTCTAATTGTTAATTATTTAATTATGACTCTTG
AGTTGTGAGAAACTCTGAGAAGCTCAGGGCTTTCAGGGAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_002670225.1|170925_171618_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225818
NZ_CP022386.1|WP_095909310.1|176248_178732_+|endopeptidase-La	unknown	unknown	gnl|CDD|223542
NZ_CP022386.1|WP_002670285.1|169538_170450_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl|CDD|234626
NZ_CP022386.1|WP_002669717.1|180594_181047_+|DUF2750-domain-containing-protein	unknown	unknown	gnl|CDD|378546
NZ_CP022386.1|WP_095909308.1|174290_174881_-|PorT-family-protein	unknown	unknown	gnl|CDD|372635
NZ_CP022386.1|WP_002670232.1|172714_173302_-|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|372635
NZ_CP022386.1|WP_002670265.1|165919_166873_-|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl|CDD|236686
NZ_CP022386.1|WP_002669750.1|181263_181731_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_002670164.1|171614_172694_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|225814
NZ_CP022386.1|WP_002670158.1|166879_168019_-|AAA-family-ATPase	unknown	unknown	unknown
NZ_CP022386.1|WP_002670153.1|168037_168712_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl|CDD|234581
NZ_CP022386.1|WP_002670184.1|170471_170912_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909311.1|178847_179144_+|ErpK-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909312.1|179218_180553_+|signal-recognition-particle-protein	unknown	unknown	gnl|CDD|236780
NZ_CP022386.1|WP_095909314.1|183233_184979_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP022386.1|WP_095909315.1|185052_185598_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909313.1|181755_183231_+|RNA-polymerase-factor-sigma-54	unknown	unknown	gnl|CDD|235648
NZ_CP022386.1|WP_040360347.1|168713_169328_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_002679268.1|173395_174031_-|PorT-family-protein	unknown	unknown	gnl|CDD|372635
NZ_CP022386.1|WP_095909309.1|174977_175913_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_002670225.1|170925_171618_-|response-regulator-transcription-factor	gnl|CDD|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	1.29895e-46
NZ_CP022386.1|WP_095909310.1|176248_178732_+|endopeptidase-La	gnl|CDD|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP022386.1|WP_002670285.1|169538_170450_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl|CDD|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	4.50129e-129
NZ_CP022386.1|WP_095909308.1|174290_174881_-|PorT-family-protein	gnl|CDD|372635	pfam13568, OMP_b-brl_2, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	7.72527e-11
NZ_CP022386.1|WP_002670232.1|172714_173302_-|outer-membrane-beta-barrel-protein	gnl|CDD|372635	pfam13568, OMP_b-brl_2, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	4.13057e-07
NZ_CP022386.1|WP_002670265.1|165919_166873_-|signal-recognition-particle-docking-protein-FtsY	gnl|CDD|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	1.22336e-171
NZ_CP022386.1|WP_095909313.1|181755_183231_+|RNA-polymerase-factor-sigma-54	gnl|CDD|235648	PRK05932, PRK05932, RNA polymerase factor sigma-54; Reviewed.	2.73496e-130
NZ_CP022386.1|WP_002670164.1|171614_172694_-|sensor-histidine-kinase	gnl|CDD|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	1.3404e-34
NZ_CP022386.1|WP_002670153.1|168037_168712_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl|CDD|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	1.778e-135
NZ_CP022386.1|WP_002669717.1|180594_181047_+|DUF2750-domain-containing-protein	gnl|CDD|378546	pfam11042, DUF2750, Protein of unknown function (DUF2750). This family is conserved in Proteobacteria. The function is not known.	3.71476e-25
NZ_CP022386.1|WP_095909312.1|179218_180553_+|signal-recognition-particle-protein	gnl|CDD|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP022386.1|WP_095909314.1|183233_184979_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.09103e-155
NZ_CP022386.1|WP_002679268.1|173395_174031_-|PorT-family-protein	gnl|CDD|372635	pfam13568, OMP_b-brl_2, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.51907e-18

Protein sequences

>NZ_CP022386.1|WP_002679268.1|173395_174031_-|PorT-family-protein
MKKIITFVALIALTATATAQNESMGFGIRGGGSITGYNGKTEANYTNVKYKAGYYVGIFSDSQLLPFLDLRTELLFSSYGAKWEFTQGNEKYSNTLHTQYINLPILARLKIGNLGILAGVQGGILVNKPSLENTFNGRTVKLDRSDFAKFDFGAVVGAEFNVTDHFLIDIRFNQGLVNALNSSNSSVRNLNISSNNNFLNVSYTLGVGYRF
>NZ_CP022386.1|WP_002670232.1|172714_173302_-|outer-membrane-beta-barrel-protein
MKKIITIIALIALTATATAQVKFGVHAGAGIGLMSKDVHDDRYEGQNKTDKEPFSTSSYGGFFVEIPASEKLLLDLGAMYTNYSTIGKGKTMLHRIDVPLAIKYDISGLRPKVGGYVSYIPGVTSFENKYRSLTRKDIEKFDYGALFGLEYNFNEKYFIETNFYLGLANLLTKDPRHSSDYLRTRSILIGVGYRF
>NZ_CP022386.1|WP_002670164.1|171614_172694_-|sensor-histidine-kinase
MNENPYIFLKNNFFLQFLIADRFRIYRHIVACSSLLLFFILGRQWGDYEGMIDYWDWIEKWLGITATFYLNMYVLIPRFFFKGKLATYIILLTLWVLFMLGSTYYLNFVLWKDYMIGKEIKIASEIPVSVAIFSSMVYIVPFIMTSTLIKIFQVWVKDSERMQELERQATESELQALRSQIQPHFLFNMLNSINTLLYIDPEKASYTITKLSDFLRHLLYQTHEEQVFLSSELRFLNDYLSLEAMRRDDFTYELTYSEKNLQGIQIPPNILLILAENAVKHSVDTLSPTYIYMKCEEKEGLLHFSVRNSVPLEPHRKHKCSGIGLPNLNRRLELLYGERFSLSQERLPQEYIVTLTLPL
>NZ_CP022386.1|WP_002670225.1|170925_171618_-|response-regulator-transcription-factor
MNCLIIDDEPLARIGMERLIRQYSNLKVVGTFKNAVGVTDFLKKNEVHLLFLDIEMPGINGLELAKILPEQTLVIFTTAYSQYALESYEVDALDYLVKPITPERFKKAVAKAESYHQLLSEQKTDLEATDAQYISIRANRRNYRIAHSDILYIEALKDYVIIHTFTDRYITWINLKNIHSQLPESVFVRVNKSYVVNTQHITSYTHQFVYIGDTEIPIGRTYEVIEKLTH
>NZ_CP022386.1|WP_002670184.1|170471_170912_-|hypothetical-protein
MSSISLLLCRALMIEFVVILLSLLGVGSLFFGIEALGIIINFFIFILVGAICCIPIAIGIGEYLSRSNKFLIKKLPLGILLMLFFYSFGVFSSITIISIGQGKGFVSMEELLEVIAFSLLLGAFPSFGVGIWLDGKLLAMIKPPEE
>NZ_CP022386.1|WP_002670285.1|169538_170450_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MNLLINIVGTTAIGKTALAIVLARHFKTEILSCDSRQFYREMSIGTAVPSREELATAPHHFIQHKSIFDTYSVGDFEREVMELLPKLFARRKLVIMVGGSGLYNDVILKGLDEFPPIKEGVRESLNALYKEKGIGVLQEQLRALDPTYCLKVDMQNPQRIIRALEVCLSGDYPYSYYLQQKSTQRDFSVISIGLTAEREVIYERINQRMEVMLQAGLLQEIERLLPYRHLNALQTVGYREFFDFWEGKVSLAEAIENAKMNTRRFAKRQLTWFKKSEDIQWFDYKEDRGKIIERIETQLLSKA
>NZ_CP022386.1|WP_040360347.1|168713_169328_-|hypothetical-protein
MTKRMFIISLGLLAPFFATAQEEQTTQQTPQENEKQYPATIEGQYDQLVEKAGNWEKYKLIKKESIYSFKRFMLDSLKAQKQVLREKLDTISSQSSQIKQLNQKITSLESDLDKEKNRNNSIEFLGMTIEKGLYSAVVWGIIIILAIFLAVFVSRFSRSNSITRGALKDLESLQNEYEEYRTKAIEREQKVRRQLQDEINKHRS
>NZ_CP022386.1|WP_002670153.1|168037_168712_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MRIDIIAVVPELLQSPFEHSIFKRAVEKGLATVHFHDLRQYGLGNYKQIDDYSFGGGAGMVLMIEPIDACISALKAERTYDEVIYLTPDGETLSQPMANALSLKENIIILCGHYKGVDQRVRDHFVTKEISIGDYVLSGGELAAAVLSDAIVRLIPGVLSDETSALTDSFQDNLLAPPIYTRPAEYKGWKVPDILLSGNTPLIENWREEQAYKRTEERRPDLLQ
>NZ_CP022386.1|WP_002670158.1|166879_168019_-|AAA-family-ATPase
MKILESKYYRAINILRVNGDDEIQLYDKHRFASYRNPYRILLSDILCDIYLEDDDLIIYRDQLQHFEKCSDFYTLSYASKSNRLYEDEECYYHPELEVFLLISYNLSNDYDNELFEEGICKVNYVYYENKNPKAKEHLTTLFAEYLQKHQSKKAKVSILLKNQNGFDLKTHMIKPFRIDFERMYNDDFLEIHNRVKKSITDENKGVVLFHGIAGSGKTNYIKWLTSQVPNKKFIFVPTSMIASLTDPSFMGVLIDHKNSVLVLEDCENYIAERTAYNSNTDVVSSILNIADGMLSDVLECQLICTFNSDISKIDSALLRKGRLIAEYKFKELTVEKCNSYLRSIGKEPNITSPCSLAELTNMETKALKEDTNSPKIGFK
>NZ_CP022386.1|WP_002670265.1|165919_166873_-|signal-recognition-particle-docking-protein-FtsY
MNFFKKLFSSDKKETLDKGLEKSKTSFFDKLTRAIAGKSKVDDDILDELEGVLVSSDVGVDTTLKIIERIEKRVAQEKYLGTSELNRILREEIAALLSQTQRGEEVDFSVPSNKKPYVIMVVGVNGAGKTTTIGKLAYQFKKKGLKVVLGAADTFRAAAIDQLQVWAERVGVPLVKQQTGSDPASVAYDTLSSALSQGADVVIIDTAGRLHNKVNLMNELSKVKRVMQKLLPETPDEILLVLDGSTGQNAFEQAKQFTLATEVNALAITKLDGTAKGGVVIGISDQFQIPVKYIGVGEGIEDLQVFNKYEFVDSFFK
>NZ_CP022386.1|WP_095909308.1|174290_174881_-|PorT-family-protein
MKKIIILTALIAFTATATAQVKFGVRGGYTLSLVSKSIHTDRYENQAHSESASSCGSAYAGLTAEVSASEKWFLDIGLIYINQVTIGEGSTMLHNINLPIAVKYDISGFRPKVGIYASYIPGVTSFEDEHRSLTKNDLKKFDCGATFGLEYNFFDRFFIEANFNLGLANLLKEDPRHSSDYLRTRSILVGVGYRFN
>NZ_CP022386.1|WP_095909309.1|174977_175913_-|hypothetical-protein
MKEIFTFITLFLGVNSFAQISVKTEYISNSKFYDAVSDSNIGDGSAMIYSVGALVPLSMKAPEEDDPYQRPTLWGVGLNGSFVQMYNHHFPMGKELPSQVMNLGATFLHLRPLKERWSMLMALGAGSYTPENRLSSIHMGENVVANGAFVLVWHWRPNIEIGGGVALNNTFGYPMVFPAFYFKYNGAFSDKFTIEVGSIDGLKVALGYNYRENLDFKLIANMGGYSAYLRRNGEKEIFSQQTFVVGLQPEFKIGKHVSIPLTVGGSFIRSGRYRERKLSAMFASEAKNEDGSSRSSQFNPALYFAAGVTIK
>NZ_CP022386.1|WP_095909310.1|176248_178732_+|endopeptidase-La
MKIGNFDIFSSEEEPEIHMEVIPISLSEMAKDVSKDQEESEEEEDPFPEQLPILPVKNMVLFPGALSSITIRRDSALELINDARDSRLIGVVSQRSNEEEATPENLYSIGVVAHIIKVLKTPEGTTHILVQGRDRFQIESFTATTPYIVAKIKEVPEIVPKEDDQEFLSSVEVVKDISLKLAKELPEGNQEIAFTIQNIENNYFLLNYVASSFPLSVTEKQEILEQDSLLTRAWTIIKYLGVELQKASLRKEIQKKVHIDFDKQQRDYFLHQQIQTIQKELGNESFEADIEKFKQQAKEKKWNEKVQKHFDKELAKLQRLNPQMPDYAIQRNYIDLLLDLPWGVYSKDKFDLKKAQKILDKDHYGLEDVKRRIIEYLAVLKLRNDMKSPILCLYGPPGVGKTSLGRSIAKALGREYVRMALGGLRDEAEIRGHRKTYIGAMPGRILQLIKKAGTSNPVFVLDELDKLSIGYGGDPSSAMLEVLDPEQNNEFYDNFLEIGYDLSKVMFIATANDLSTIQPALKDRMEIINISGYTIEEKVEIARHFLLPKVLKEHGMIDKHIQLGKKEIERIIEGYTRESGVRNLEKQIAKIVRYIARAIAMKEEYNPKISLEDIRKILGIPSEHDKYEDNEVAGVVTGLAWTSVGGDILFIESTFSKGSGDLSITGNIGTVMKESATIALEYIKSHAQQFGLDTRIFEQYKIHMHIPEGATPKDGPSAGIAMLTSIFSVLTQRKVKKNLAMTGEITLRGKVLPVGGLKEKILAAKRAGIKEIILCKENEKDINEIKTQYLEGLTFHYVTDMQEVLQLAVTQEKVKDAKEFSFEKVKS
>NZ_CP022386.1|WP_095909311.1|178847_179144_+|ErpK-protein
MDKEQFLKDAQDKISALTEKISSLTESLGLQSGDLKAKAQEEINKLLENKSALTEKFEALKSVPEDKWEEAKKAFNELLSGNTEGLLQKGIDAVKNLF
>NZ_CP022386.1|WP_095909312.1|179218_180553_+|signal-recognition-particle-protein
MFDNLSNKLEKALHVLKGHGQITEINVAETLKEVRRALLDADVNYTIAKEFTAKVKAKALGSNVLTTLQPGQLMVKIVHDELTELMGGDATGVNLSGNPSVILMSGLQGSGKTTFSGKLANFFKNKKNKKPLLVACDVYRPAAIDQLHIVGQQIGVEVFSEKENRNPVDIAQKGLAYAKSNGYNVVIIDTAGRLAVDEHMMKEIADIHHAVTPQETLFVVDAMTGQDAVNTAKAFNDVLNFDGVVLTKLDGDTRGGAAISIKSVVNKPIKFVGTGEKMDAIDIFYPSRMADRILGMGDVVSLVERAQEQFDEEQARKLQKKIAKNQFGFDDFLSQIQQIKKMGSMKDLLGMIPGVGKAVKDLDISDDAFKYIEAIIYSMTPEERSNPAIINTSRKNRIAKGSGRNISEVNQLLKQFDQMSKMMKMMQGGGAKQMMRMMQSMPRM
>NZ_CP022386.1|WP_002669717.1|180594_181047_+|DUF2750-domain-containing-protein
MQQELIDSYYHFVREVVAKGVVYCLKDEKEYVASCISSQFTTEDDEEVGVLAFWSDKEGAENCKQEEWEGYHLSEIPLAEFMENWCLGMAQEDIVAGIDFDSTLFGYEEAPLRLLSSLIEEVEANDVKLTFNSFSSLGDIKEYIKELEEE
>NZ_CP022386.1|WP_002669750.1|181263_181731_+|hypothetical-protein
MKNFFTLVSILFCFALQAQEAQKASAQRFIEAVINTSEEDYPVLYPMLKISKIIPPEEGGMAKLSQVFSVLKNQLQNHDFVIYSSEEALDLISRETGNYRASDILTSEKGVVFYVYLPRYKRFLVRFPIVVNDKNEIIAINIDYCKDNTICLQYL
>NZ_CP022386.1|WP_095909313.1|181755_183231_+|RNA-polymerase-factor-sigma-54
MLKQQLQLKLTQKLSPQQIQLMKLVQLPTVAFEQRVKEELDENPALEPSDNENWDEEEDYEDPFDTGEEAFEDSQIIQADAINVDEYLSDDEIPDYRLYSNSYNNSDEEYGQPYREELSFHQYLLDQLSTFRLDERQHDIAEFLIGSINDNGYIRRSMRDIADDLAFTQNLYTTEEEVERVLKTVIFQMEPAGIGARSLQECLIIQLKHKPQTAITELAIRILEENFDLFSKKHYDKLTQRYDISEEYLKEVIQEIEKLNPKPGSSYSEGGKYSEQIVPDFTITVNDGQLELSLNGRNTPQLHISQEYTEMFKTYRDSAEKDKQKQKEAVEFIKQKLDAAKWFIDAIKQRQNTLLVTMNAIMLHQKEYFLTGDETKIKPLILKDIAESIGMDISTVSRVANSKFVSTPYGTKPVKAFFSEAIKNDEGEDISTHEVKKILQTIIEGEDKRKPYTDDKLMELLKQEGYPIARRTIAKYREQLDIPVARLRKEL
>NZ_CP022386.1|WP_095909314.1|183233_184979_+|ABC-transporter-ATP-binding-protein
MKHLTYINKYFYKYRKQLIWGVLITIIARLFSLVMPKSVQYAIKAVEDYLASPTSEKSIGSDLLLYCLVIIGATLLSGFFTFWMRQLIINVSRYIEYDMKNEVYQKYQVLSQQFYKQHRTGDLMNRISEDVGKVRMYTGPALMYSVQTITLFLCSIPLMFYTSPTLASYALLPLPILAVLVYFISRKINVKTLEVQRFLSDISSFSQETFSGIQTIKAFALETPTQERMKALSREGRKKNLQLLRIQAWFFPIMIFLIGISVIFVIFIGGRLYIKGEIDSIGVITEFTIYVMMLTWPVATVGWVSNIVQQAEASQGRINEFLQEKPHIENTCLSSTPIFGDIRFDHVTFTYPDTQVTALKDISFHIPKGKSIAIIGRTGSGKSTILELITRMYDVEQGQILIDERNIKELNLNDLRKSISVVPQDCFLFSDTIAHNIKFGKPQASEAEVIQVAKLAQVHDNIMDFKDNYQTVLGERGITLSGGQRQRVSIARALLKEAQIYLFDDCLSAVDTDTEEKILQNLSQVAQQTTRIIVSHRVSVARNADYILFLDQGQLIGEGTHAKLYQENEQYRNYYDTQVVE
>NZ_CP022386.1|WP_095909315.1|185052_185598_+|hypothetical-protein
MRKYIILLVAFLSLTACSDGKLTPSQAKDLVEESLEGKPLYETAYITLGEVKLRTQKDGEKIKQIKRLEDEDYLSLEEIKMKKKWLSNDSVWVVNIKCTDKALPYIIELKETRAKVKTLEYTLSDEVTVEQKGEKTATITATLLKKETPFSFLNKKAGGQDFIQKKYKAKYREKEGWTLSK

Crispr_ID: NZ_CP022386_2

• CRISPR_ID: NZ_CP022386_2
• CRISPR_location: 199122-199230
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP022386_2

Consensus_repeat	Method
CAAGTGGCTGCTACCCAAGGAAAAACAACTACTA	CRISPRCasFinder

spacers of NZ_CP022386_2

>2.1|199156|41|NZ_CP022386|CRISPRCasFinder
CACCTGTTCAAAGTGGACAAAATGTGACCACTCCTCAAGGG

CRISPR arrays and Neighbor proteins around NZ_CP022386_2

CRISPR arrays

The CRISPR arrays of NZ_CP022386_2

>merge|NZ_CP022386|2|199122-199230|CRISPRCasFinder
CAAGTGGCTGCTACCCAAGGAAAAACAACTACTACACCTGTTCAAAGTGGACAAAATGTGACCACTCCTCAAGGGCAAGTGGCTGCTGCCCAAGGAAAAACAACTACTA

>NZ_CP022386|2|2|199122-199230|CRISPRCasFinder
CAAGTGGCTGCTACCCAAGGAAAAACAACTACTA	CACCTGTTCAAAGTGGACAAAATGTGACCACTCCTCAAGGG
CAAGTGGCTGCTGCCCAAGGAAAAACAACTACTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_095909324.1|195064_196585_-|DUF853-family-protein	unknown	unknown	gnl|CDD|283518
NZ_CP022386.1|WP_002668128.1|210490_211591_-|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NZ_CP022386.1|WP_095909335.1|207758_210299_-|type-I-DNA-topoisomerase	unknown	unknown	gnl|CDD|236048
NZ_CP022386.1|WP_095909328.1|200479_201082_+|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl|CDD|234770
NZ_CP022386.1|WP_095909320.1|190198_191608_-|alkaline-phosphatase	unknown	unknown	gnl|CDD|293736
NZ_CP022386.1|WP_095909317.1|186167_188279_+|glycoside-hydrolase-family-97-protein	unknown	unknown	gnl|CDD|371140
NZ_CP022386.1|WP_095909319.1|189348_190176_-|HAD-family-hydrolase	unknown	unknown	gnl|CDD|369792
NZ_CP022386.1|WP_095909327.1|199713_200478_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP022386.1|WP_095909329.1|201089_202394_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341239
NZ_CP022386.1|WP_095909321.1|191649_193119_-|GHKL-domain-containing-protein	unknown	unknown	gnl|CDD|227333
NZ_CP022386.1|WP_095909322.1|193352_194474_+|GTP-cyclohydrolase	unknown	unknown	gnl|CDD|223532
NZ_CP022386.1|WP_095909334.1|207035_207362_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NZ_CP022386.1|WP_095909318.1|188367_189342_-|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl|CDD|129820
NZ_CP022386.1|WP_095909333.1|206029_206956_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909325.1|196801_197842_+|thiamine-phosphate-kinase	unknown	unknown	gnl|CDD|100030
NZ_CP022386.1|WP_095909323.1|194463_195057_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909331.1|204290_204875_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909332.1|204896_205973_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909330.1|202595_204074_+|IMP-dehydrogenase	unknown	unknown	gnl|CDD|376340
NZ_CP022386.1|WP_095909316.1|185640_186102_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_095909324.1|195064_196585_-|DUF853-family-protein	gnl|CDD|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP022386.1|WP_095909335.1|207758_210299_-|type-I-DNA-topoisomerase	gnl|CDD|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
NZ_CP022386.1|WP_095909328.1|200479_201082_+|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl|CDD|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	5.83335e-99
NZ_CP022386.1|WP_095909320.1|190198_191608_-|alkaline-phosphatase	gnl|CDD|293736	cd16012, ALP, Alkaline Phosphatase. Alkaline phosphatases are non-specific membrane-bound phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH. Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymatic activity. Mammalian alkaline phosphatase is divided into four isozymes depending upon the site of tissue expression. They are Intestinal ALP, Placental ALP, Germ cell ALP and tissue nonspecific alkaline phosphatase or liver/bone/kidney (L/B/K) ALP.	1.21148e-92
NZ_CP022386.1|WP_095909317.1|186167_188279_+|glycoside-hydrolase-family-97-protein	gnl|CDD|371140	pfam10566, Glyco_hydro_97, Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands.	4.22804e-141
NZ_CP022386.1|WP_095909319.1|189348_190176_-|HAD-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.59957e-60
NZ_CP022386.1|WP_095909321.1|191649_193119_-|GHKL-domain-containing-protein	gnl|CDD|227333	COG5000, NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms].	6.94847e-44
NZ_CP022386.1|WP_095909329.1|201089_202394_+|AMP-binding-protein	gnl|CDD|341239	cd05913, PaaK, Phenylacetate-CoA ligase (also known as PaaK). PaaK catalyzes the first step in the aromatic degradation pathway, by converting phenylacetic acid (PA) into phenylacetyl-CoA (PA-CoA). Phenylacetate-CoA ligase has been found in proteobacteria as well as gram positive prokaryotes. The enzyme is specifically induced after aerobic growth in a chemically defined medium containing PA or phenylalanine (Phe) as the sole carbon source. PaaKs are members of the adenylate-forming enzyme (AFE) family. However, sequence comparison reveals divergent features of PaaK with respect to the superfamily, including a novel N-terminal sequence.	3.83307e-134
NZ_CP022386.1|WP_095909327.1|199713_200478_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.41412e-31
NZ_CP022386.1|WP_095909322.1|193352_194474_+|GTP-cyclohydrolase	gnl|CDD|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	0.00214437
NZ_CP022386.1|WP_095909334.1|207035_207362_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	3.57595e-14
NZ_CP022386.1|WP_095909318.1|188367_189342_-|tRNA-dihydrouridine-synthase-DusB	gnl|CDD|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	1.3962e-120
NZ_CP022386.1|WP_095909325.1|196801_197842_+|thiamine-phosphate-kinase	gnl|CDD|100030	cd02194, ThiL, ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the conversion of this intermediate to thiamine pyrophosphate. The N-terminal domain of ThiL binds ATP and is related to the ATP-binding domains of hydrogen expression/formation protein HypE, the AIR synthases, FGAM synthase and selenophosphate synthetase (SelD).	1.034e-111
NZ_CP022386.1|WP_095909330.1|202595_204074_+|IMP-dehydrogenase	gnl|CDD|376340	pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain. This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains pfam00571 are inserted in the TIM barrel. This family is a member of the common phosphate binding site TIM barrel family.	0
NZ_CP022386.1|WP_002668128.1|210490_211591_-|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	4.78186e-165

Protein sequences

>NZ_CP022386.1|WP_095909325.1|196801_197842_+|thiamine-phosphate-kinase
MLEDKNTHRTDLSQLGEFGLIDLLTRDFPLHNPSSLKGIGDDAAVIDFGEEKAVVSTDLLIEGVHFNLAYMPLKHLGYKAIMVNLSDICAMNALPTQVTVSLAVSNRFPVEALQELYEGIRLACDIYKVDLVGGDTTSSTRGLILSVTALGKAPLEKIVYRNGAKENDLIVVTGDLGAAYMGLQILERENEVFKVNPNLQPDLEPYQYLIERQLKPEARKDIISLLEALEVRPTSMMDISDGLSSELLHICKQSHVGCRLMEDKIPLDPTLINVCEEFALSSTMVALSGGEDYELLMTIAPADYDKIKGNPNLTVIGYITDESLGCNLITRANEAIPLKARGWNAF
>NZ_CP022386.1|WP_095909324.1|195064_196585_-|DUF853-family-protein
MSIEKFKEVIEAGYTVSGKYITLGGAMYEGKAIANLFVNIPLKNLNRHGLIAGATGTGKTKTLQALTENLSKEGVPTLLMDLKGDLSGIAAIGEEKSFIKERHTQMNLPYTPEAFPVELLTISKQDGVRMRATVSEFGSVLLSRILDLSDVQEGVLAVVFKYCDDHQYPLLDLKDLKKVLQYATEEGKSEFESEYGRVAASSTSAILRKIVELENQGAELFFGERSFETEDLLHTDEKGRGVVNIIRLTDIQDRPKMFSTFMLCLLAEIYNTFPEIGDQEKPKLVIFIDEAHLIFNQASKALLNQLENIVKLIRSKGVGLIFCTQTPTDVPDAVLSQLGLKIQHALRAFTAKDRQAIKLTAQNYPETSFYNVPEYLTSLGTGEAFVTALDSKGRPTPLVATMMRAPMSRMDILTDTEIKALLDKSVLKAKYNEVIDRESAYEILNAKIANEAPKEDASKKTETKSTAPKTSSAPKKSTAQNPIIKMLTSATFVRGVFGVLSKLMKK
>NZ_CP022386.1|WP_095909323.1|194463_195057_-|hypothetical-protein
MKLKKHIFPPAFFLAGITSLLVGCSQVDKKFLITDSSVGLLTRGTKITQLDSLYQKDSLVKTSLEGEFRYISEERFLIYERGKEKKQLLELTPNIPLDGSPQYIQGVQVLDDRYTTKEGISLNSTFGDIKKVYKEFDFEQLLSTVIVMPKGSNLYFAFDQKELLPALDDTYTIESIPDTAKVKRLLLNWAEGTSPTQ
>NZ_CP022386.1|WP_095909322.1|193352_194474_+|GTP-cyclohydrolase
MITVKRVDNTKGMLDFVKFPFFLYKDSKTWVPPLISEELATFDPKKNPAFENCEATFFLAYNEKGTIVGRIAVIINHYEINRGVRKVRFGWLDMIDDLKVTDALLKKALDKAHELGLLYVEGPMGFSNMDKVGIQTFGFEHIGGMATWTNYPYYAQHLEKLGWVKEKGYIESFFYLKDVDFEPYKKAGDVVERRYGLSYAPIKTNKDILPYVDEMFDLFNTSYANLSSFIPVSDKQKEYFKKKYIPFVLPEFIKFILDKEGKIICFAIMIPSFSEALQKAKGKLFPFGFYHLWKARRNPKVLEFYLIGISPEYQSKGIPAMLFRDCYLLFKEKGVEQCIITPELEDNILVQKLWKNFNPTTFSRRATYKKTIE
>NZ_CP022386.1|WP_095909321.1|191649_193119_-|GHKL-domain-containing-protein
MSAFHSLRFRIFVSLIGITILSFITIAIVTIYQYRNQSRIYHNERLLRKEQQLAMQLRYVFSQTTFPVEDKYIPVIFREEIYRIADIENINFNLYTINGTFLISSQAGLRENKELHCIPDSILTALSSSVDKRLVFQAPEEGGSYQYSYSYVNDLQYKPLLIVHIPHFENDTFNEGFLQDSLYNLGSAYGAILLLTIVVALVISRYITRSLKEIQHRLRTTHFLGKNEKINVKNTTTEIGELIFSYNEMVDEIEKSKKALAKIEREKMWKDMAKQIAHEIKNPLTPMRLSVQNFERRFTPEDPQCREKVANFTQMLLQHIDTLSDISDAFSSFVSMPAQKKELSDINAIIRRTIAVFDLPYIHFESSQETIELCVDRNQMNRMLTNLLKNALYATDSTPTPLIEVTSFIEGNYAYIVVKDNGSGVPIELQERIFEPKFTTKNTAGSGLGLAMVKHIVSAHAGKITLSSEVGKGASFTIKLSGVGQETNL
>NZ_CP022386.1|WP_095909320.1|190198_191608_-|alkaline-phosphatase
MERRNFLKNSLLAGLGSLLVPSVAQAQASESFGRKRAKNIIYLVSDGMSIGTLVMADLYSKRILGRSSAWFSLYEQKLAVKASMDMQSASSVVTDSSAASSSWGSGHRIINGMINVGVNGEQYTPILQKFKKAGKKVGCVTTVPITHATPAGFCTNSKERKAQPKIAENYLDLRFDVMMGGGDNYFNAGKRKDKQDMYVKYLEKGFTVVKNVSQMNAAPKNVPLLGVFDKDALPYTLDENNTTKNATIPTLAQMTQKAIDMMADHKQGFVLQVEGGKVDWAAHGNDIGALLFDQLAFDDAVRVAIDFAKKDGNTLVVITSDHGNANPGLIYGKECNKNFDNLAHFLHTNDFTLQSINLTDSVSQVRDLLTHNFGNIPFSQEEAKEILSFYTEGKQEDGLYNYKKLPYRLLAEIQKKHTSVGWISMDHSSDYTELAMYGPGSQNLPPFIENYKMHNFLLEAAEVDMLEKY
>NZ_CP022386.1|WP_095909319.1|189348_190176_-|HAD-family-hydrolase
MAYKILFSDIDGTLLDAERTLSEKTIKVLSHLKYQFPIVLISSRMPIQMHYLQEKAGILGMPLIAYNGALVIDKDRKVLRSTEIPFSLCQQIVALNQQYTGGNLHISFYHFDEWYVPKADQWAQREERNTCTTPMVKTNQEVLSLWGFQNRGAHKLMLMGEEELVEAMWQVLQREMTGQLQLYRAKNTYIEITLQGVSKLTGIEAFLAHQKGISLGDAIAFGDNYNDQEMLQAVGLGVAVANARDEVKAVANDTTHHHKEDGVARYLAKMFDIEL
>NZ_CP022386.1|WP_095909318.1|188367_189342_-|tRNA-dihydrouridine-synthase-DusB
MVKIGNVTLGEFPLLLAPMEDVSDPPFRRLCKKYGADMLYSEFISSEGLIRDAIKSRKKLDIFDDERPVGIQIFGGDEEAMALSARIVETVSPDVVDINFGCPVKKVVAKGAGAAVLKDIDLMVRLTQAVVKSTHLPVTVKTRLGWDSETINIEEVAERLQDVGIQALSIHARTRVQMYKGHSDWSYIAKVKNNPRIHIPIFGNGDIDSPEKALEYKERYGVDGIMIGRAAIGYPWIFQEIKHYMATRELLPPLTLSERAEAALQHLLWAVEWKGERLGILETRRHYSNYFKGIPHFKEYKQQLVTLDDLEALKEILIKVKSEE
>NZ_CP022386.1|WP_095909317.1|186167_188279_+|glycoside-hydrolase-family-97-protein
MKSFILTLSVWLFAYTFSPVKAQELASPNGKVVLSFSLTKEGTPSYKISYKNKSVIKESTLGFLLKKGESLNAHFKVVDSKRTTFKETWRPVWGEESDILNHYNELCVFLEQNTTHRKMNLRFRVYNDGVGFRYEFPEQKELTYFVIAEELSQFAMAGDHTAWWIPGDYDTQEYDYTQSKLSQIRSLMPQAVIKNVCQTPFSPTGVQTSLMLKSQDGLYINLHEAALVNYPCMHLNLDEQHLIFQSHLTPDAKGDKGYLYTPCHTPWRTIMVSDDAREILASRLILNLNDPCALSDTSWIKPVKYIGVWWEMITGKSSWAYTNDFPTIDLDKVNYTKARPNGTHAANNEKVRRYIDFASQHGFDQVLVEGWNIGWEDWFDNSKDYVFDFVTPYPDFDLKGLNAYAHSKGVKLMMHHETSASLRNYERHMEKAYQLMNDYGYNSVKSGYVGSIIPRGEYHYGQWAVNHYLYAIKEAAKHKIMVNAHEAIRPTGLCRTYPNLIGNESARGTEYEALETIKPFHTTILPFTRLQGGPMDYTPGIFETDISKVNPQNPHKLSSTLAKQLGLYVTMYSPLQMAADLPENYEKFLDAFEFIKKVPVDWQKSLYLEAEPGQYITIARKDKHSNNWFVGNTSNENGHTSVISLDFLDKGHVYEATIYADAPEADFQNNAKAYTITKKKVNAKTKLTLKAARGGGYAIMINY
>NZ_CP022386.1|WP_095909316.1|185640_186102_+|hypothetical-protein
MKKSTSILLFQGLISVVSGILITQMSLLGRIGIHTMYRQFLVFRSWWKTALLLFAVQCLLLALLYGVRKAMSLSSAKKVAWILLLVGILGAGATYWDFSHTMHKVMKAKFHFGFYLFWLGWAVSCLYFISVKDEERKVTNEEIEKIKEVKNEE
>NZ_CP022386.1|WP_095909327.1|199713_200478_+|alpha/beta-hydrolase
MINLFRKKEDKFSYIEKGEGTPIILLHGLMGALSNFESTIDFFSKKYKVVAPELPIYDLPLLSSTVKSLTNWLARFITYKGFDQVILLGNSLGGHIGLLYTKLHPKKVKALILTGSSGLYESAMGDSYPKRGSYEFIEKKCQDVFYDPKTATKELVDEVFAIVNDRTKVIKTLAIAKSAIRHNMAKDLPKMTLPVCLIWGKNDPVTPPRVAEEFNELFPNATLYWIDKCGHAPMMEHPEEFNKILNNWLTDKDL
>NZ_CP022386.1|WP_095909328.1|200479_201082_+|YihA-family-ribosome-biogenesis-GTP-binding-protein
MEIKQATFVVSNTQVAKCPTHKLPEYAFIGRSNVGKSSLINMLTNHKGLAKTSSKPGKTQLINHFLINKEWYLVDLPGYGYAKVSKQSKKTFQQFIIDYFKKRRELVCAFVLVDIRHEPQKIDLEFMQWLGENAIPFAIVFTKADKLTEKQIQEHVASYSEILLQQWEEMPPYFITSSENRLGKEDLLSYIETINQSLKA
>NZ_CP022386.1|WP_095909329.1|201089_202394_+|AMP-binding-protein
MSFPIPVIETQSKDAIRLFQEEKLRELLQYLKEKSPYYQRLFRENNIDITQIQHLEDLQRLPTTSKDDLQRYNDDFLCVPKEAIVDYASTSGTLGKPVTFGLTDRDLDRLAYNEAISLSCAGISQGDVVQLMTTIDRRFMAGLAYFLGIRHLGASIVRIGAGIPELQWDSILSYHPTYLIAVPSFLLKLIEYAEKNGIDYRHSSVKGVVCIGETLRQQDFSPNLLTDKIMEKWPELRLYSTYASTEMSTTFTECDALQGGHHHPELIITEVLDDEGNPLPYGQLGELTITTLGVEGMPLLRFRTGDMVTLHDTPCSCGRNTLRVSPVVGRKQQMIKYKGTTLYPPALMDLLTEFAQVENYIIEISSNEILTDEILIKIGTCEPSEALKEEIANHFRAKMRVVPKIEFYPVDTIEEQLYPKGSRKPVKFIDRRGE
>NZ_CP022386.1|WP_095909330.1|202595_204074_+|IMP-dehydrogenase
MNSHNPKIISEGLTYDDVLLVPHYSEVLPREVSIQSFFSRNIPLNVPIVSAAMDTVTESAMAIAIAREGGIGVLHKNMTIEEQALQVRKVKRAESGMIIDPVTLSLTSTVGDAKHCMKEHSIGGIPIVDEQGILKGIVTNRDLRFERDNTRPITQVMTHENLVTAPEGVSMKDAEKILEKNKIEKLPVVNKDHKLVGLITFRDIANLQSKSISNKDNIGRLRVAAALGVTVDAVERAEALVHAGVDAVVIDTAHGHTRGVVSVLKKVKEHFPQLDVVVGNIATAEAALYLAKAGADAVKVGIGPGSICTTRVVAGVGYPQLSAVMQVAAALKQQNISIPVIADGGIRYTGDIVKAIAAGADCVMLGSLLAGIKESPGETIIFEGRKFKSYRGMGSVEAMQHGSKDRYFQDVEDDIKKLVPEGIVGRVPYKGELQESMHQFIGGLRAGMGYCGAKDIATLKETGKFVRITASGIAESHPHNVTITKEAPNYSR
>NZ_CP022386.1|WP_095909331.1|204290_204875_-|hypothetical-protein
MDIKKSFFMHDENGTSKKESLVDFFLSWTLRCITHKERDYQNPKLEVYCKRITSLLLFGDVEKLNQYEVQQVKTWLQWKRVDLCAEFYLLNKETQKEEKYALLLENKVYTSIHDNQLENYKQLFQQDYEGEDTFLEYVYFSCKDTLSDWEKEQCAAAGYRAYTMNEVLDLVQGDQTWDFTGNALFDEFWLSNWG
>NZ_CP022386.1|WP_095909332.1|204896_205973_-|hypothetical-protein
MCSFPIFAQQKTAYQKKIEEIQNKYLQKYGVSLSRINQLRKDKELGNAAVEALLYEKIQNYGKTHGNVDAGLILIKILKEMNAAEKLKTPAELKKEKEEIEKRIAQQKKEKQQREIMEKKKREEDIEKTSDIVRTKVRIKDSFIKWAQRGEFETTNEFNKRLSEESRNQLQKISFYEIDYIFDNELKFDIKLGMYDADNEIYPMIIEKKIGFYSYKTEEELYKKLVYKNYTGDYNFNNPKISIVTEAKIEREKAIKLKEICEEHSESIHAYGNPQFSRNIEEWILKDGYFFPITIKIGSYNDAKGELEDIEIVNLNKKGYSLISEIGFNTSDLGLSGYFPENYTFKLNNNHIENIEEN
>NZ_CP022386.1|WP_095909333.1|206029_206956_-|hypothetical-protein
MKKIILLTSLLLQIACGQSFQQGNGKQTEDLREYELKGNVKSLEYATYEAIDKSGEIVANEGKFCATRKFSYKGKILFDKNGNMIEITTSEPLPGREFNTKTIYIYDGKKLIKEEYEQYYTDNKSAVKRKSFIYEYDNKGYKTKKKIILPNGKIRDEIIYKYNSNGQLIRIEKNIGGEDAIFSEENYEYDARGNIIVIGYDGYKNIANVYLKYNDRNQLIELRGPIISDEYSGDPIPDVKVGENISYYEYDSKGNLIGERYTTTKREMKWIDSEYIRYESDDKGNWIKSIRFQDTDPISITLRTIEYY
>NZ_CP022386.1|WP_095909334.1|207035_207362_-|DUF805-domain-containing-protein
MFKSPFSFKGRIGMLEYFISVLIYIAYLLLIRNYLIDYLFQSFEDVGTAFLVLLLSLIPAIYFALAQGAKRNHDIGNSGWFILLPFNNFIILFVPSEKANNKYGEYLD
>NZ_CP022386.1|WP_095909335.1|207758_210299_-|type-I-DNA-topoisomerase
MAKNLVIVESPAKAKTIEKFLGSDYKVMSSYGHIADLPDKELGVDVAHGFKPQYLVAVDKRNLVKALKEEVKKADTVWLASDEDREGEAIAWHLSEELKLSQEKTKRIVFNSITKSAIEHAIKNPRGIDYNLVNAQQARRVLDRLVGYELSPVLWKKIRKGLSAGRVQSVSVRLIVEREREIQDFQSEVSYKITAEFLTKEGKLIKTYTHKSFPTQEAAKAFLEKNIGATFSVGSLETKPAKKSPAPPFTTSTLQQEAARKLHFSVSKTMQLAQRLYESGLITYMRTDSVNLSPEALSAAKQEIVKSYGEAYSKTRQYTSHSKGAQEAHEAIRPTDMAAHTVRAEADQVRLYELIWKRTIASQMSDASLERTQVKVNASTHTEPFIGSGEVIVFDGFLKVYLEGKDDEEEEDEGMLPAMKVGESLTSKHITATQRFTRPPFRYTEASLVKKLEELGIGRPSTYAATISTIQNRGYVERSSLEGESRPYLQLSLIKNEIKEKKLTENVGADKGKLIPTDIGMIVNDFLITHFATIVDYNFTAKVEEEFDDIASGKEDWAKMVGRFYDTFHPTVAHVEQNAVRETGERILGTDPATGKPVSVRLGRYGAMVQIGTVEDEEKPRFASLLPHQTIDSITFEEAMKLFELPRKLGVYQGKEVESNIGRFGPYIRFGDTFISLDKSLDVFSITFDEAKEVIDQKQKADAPISVYDGKEVTKGTGRFGPFIKWNNMFISVSKKYDFEHLSQSDIIFLIEEKLKKESEKVVKEWPEEGIHIEKARWGRYHLLKGKTKVELSKDTDIEAFTLAEAQSLLATKEKPKKAPATKKATTAKKAPAKASKTVAKKTVKK
>NZ_CP022386.1|WP_002668128.1|210490_211591_-|peptide-chain-release-factor-2
MVTIEQLKELSQRVENLEKYLQIDKKKIEIANEEEKTLAPDFWDSPKQAQLLVQKLQSQKKWVTDYEKSAEMVEELQIMLDFYKENAISAEEVEDFYGQTLLHIENLEFRNMLSDEGDALSAVLQITAGAGGTESCDWASMLMRMYMMWANRQGFSVKELNFQEGDVAGVKTVTLEIDGEFAFGYLKGENGVHRLVRISPFDSNAKRHTSFASVYVYPLADDTIEIEINPADISFETMRSSGAGGQNVNKVETAVRLRHHPTGIIIENSETRSQLDNKNKALQLLKSQLYEIELKKRQAKRDEIEANKMKIEWGSQIRNYVMHPYKLVKDVRSGYETTNVDAVMNGELDDFLKAYLMLMGQQNNDQ

Crispr_ID: NZ_CP022386_3

• CRISPR_ID: NZ_CP022386_3
• CRISPR_location: 348891-349458
• CRISPR_type: orTypeII
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas9

Consensus repeat of NZ_CP022386_3

Consensus_repeat	Method
TGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	PILER-CR
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CRISPRCasFinder
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CRT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	PILER-CR

spacers of NZ_CP022386_3

>3.1|348937|29|NZ_CP022386|PILER-CR
TACTCCGCGGGATAGTTGGGATAGGGCAA
>3.2|349012|28|NZ_CP022386|PILER-CR
GTAGCTTGACCAAAAGCCTCACGGAACT
>3.3|348936|30|NZ_CP022386|CRISPRCasFinder,CRT
TACTCCGCGGGATAGTTGGGATAGGGCAAT
>3.4|349011|29|NZ_CP022386|CRISPRCasFinder,CRT
GTAGCTTGACCAAAAGCCTCACGGAACTT
>3.5|349085|30|NZ_CP022386|CRISPRCasFinder,CRT
CAGGGTGGTCTACTTTTCCACCTATTGTCT
>3.6|349160|30|NZ_CP022386|CRISPRCasFinder,CRT
CTAATTCCTTTATGAGTTCATAATAGGAAT
>3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR
CAAACCATCTCGCCCCCCTCGCCCTGCGGG
>3.8|349310|29|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR
GTAATACTCTGTACCTTTTTTATCGTAAA
>3.9|349384|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR
ACCTTCATCTCGATATAAAGGCTTTTACCT

CRISPR arrays and Neighbor proteins around NZ_CP022386_3

CRISPR arrays

The CRISPR arrays of NZ_CP022386_3

>merge|NZ_CP022386|3|348891-349458|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACTACTCCGCGGGATAGTTGGGATAGGGCAATGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACGTAGCTTGACCAAAAGCCTCACGGAACTTGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACCAGGGTGGTCTACTTTTCCACCTATTGTCTGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACCTAATTCCTTTATGAGTTCATAATAGGAATGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACCAAACCATCTCGCCCCCCTCGCCCTGCGGGGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACGTAATACTCTGTACCTTTTTTATCGTAAAGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACACCTTCATCTCGATATAAAGGCTTTTACCTGTTGTTTGAGGTCACAAAATTACGAATTTGAAAGCAACTCACAAA

>NZ_CP022386|3|1|348891-349084|PILER-CR
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACT	ACTCCGCGGGATAGTTGGGATAGGGCAAT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACG	TAGCTTGACCAAAAGCCTCACGGAACTT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACCAGGGTGGTCTACTTTTCCACCTATTGTCTGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACCTAATTCCTTTATGAGTTCATAATAGGAATGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CAAACCATCTCGCCCCCCTCGCCCTGCGGG
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	GTAATACTCTGTACCTTTTTTATCGTAAA
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	ACCTTCATCTCGATATAAAGGCTTTTACCT


>NZ_CP022386|3|3|348891-349458|CRISPRCasFinder
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	TACTCCGCGGGATAGTTGGGATAGGGCAAT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	GTAGCTTGACCAAAAGCCTCACGGAACTT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CAGGGTGGTCTACTTTTCCACCTATTGTCT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CTAATTCCTTTATGAGTTCATAATAGGAAT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CAAACCATCTCGCCCCCCTCGCCCTGCGGG
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	GTAATACTCTGTACCTTTTTTATCGTAAA
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	ACCTTCATCTCGATATAAAGGCTTTTACCT
GTTGTTTGAGGTCACAAAATTACGAATTTGAAAGCAACTCACAAA

>NZ_CP022386|3|1|348891-349458|CRT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	TACTCCGCGGGATAGTTGGGATAGGGCAAT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	GTAGCTTGACCAAAAGCCTCACGGAACTT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CAGGGTGGTCTACTTTTCCACCTATTGTCT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CTAATTCCTTTATGAGTTCATAATAGGAAT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CAAACCATCTCGCCCCCCTCGCCCTGCGGG
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	GTAATACTCTGTACCTTTTTTATCGTAAA
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	ACCTTCATCTCGATATAAAGGCTTTTACCT
GTTGTTTGAGGTCACAAAATTACGAATTTGAAAGCAACTCACAAA

>NZ_CP022386|3|2|349190-349458|PILER-CR
	ACTCCGCGGGATAGTTGGGATAGGGCAAT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACG	TAGCTTGACCAAAAGCCTCACGGAACTT
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACCAGGGTGGTCTACTTTTCCACCTATTGTCTGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAACCTAATTCCTTTATGAGTTCATAATAGGAATGTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	CAAACCATCTCGCCCCCCTCGCCCTGCGGG
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	GTAATACTCTGTACCTTTTTTATCGTAAA
GTTGTTTGAGGTCACAAAGTTACAAATTTGAAAGCAACTCACAAC	ACCTTCATCTCGATATAAAGGCTTTTACCT
GTTGTTTGAGGTCACAAAATTACGAATTTGAAAGCAACTCACAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_002668348.1|356517_356937_-|DUF5606-domain-containg-protein	unknown	unknown	gnl|CDD|375774
NZ_CP022386.1|WP_095909425.1|338602_340606_+|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl|CDD|235395
NZ_CP022386.1|WP_095909435.1|357610_358063_-|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|376622
NZ_CP022386.1|WP_095909422.1|335705_336245_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909432.1|353207_354803_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP022386.1|WP_095909421.1|334537_335695_+|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|224014
NZ_CP022386.1|WP_095909428.1|343228_343837_-|YigZ-family-protein	unknown	unknown	gnl|CDD|376491
NZ_CP022386.1|WP_157909404.1|341775_342384_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911255.1|340587_341661_-|chorismate-synthase	unknown	unknown	gnl|CDD|376510
NZ_CP022386.1|WP_095909424.1|337532_338606_+|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NZ_CP022386.1|WP_095909433.1|354864_355473_-|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|238980
NZ_CP022386.1|WP_002668472.1|356950_357547_-|peptide-deformylase	unknown	unknown	gnl|CDD|234668
NZ_CP022386.1|WP_095909427.1|342496_343105_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909434.1|355469_356399_-|YbbR-like-domain-containing-protein	unknown	unknown	gnl|CDD|377947
NZ_CP022386.1|WP_095909423.1|336295_337447_+|metallophosphoesterase	unknown	unknown	gnl|CDD|277368
NZ_CP022386.1|WP_002668400.1|351916_352294_-|ribonuclease-P	unknown	unknown	gnl|CDD|234989
NZ_CP022386.1|WP_002668555.1|350625_351819_-|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234813
NZ_CP022386.1|WP_095909430.1|349553_350561_-|ketoacyl-ACP-synthase-III	unknown	unknown	gnl|CDD|236475
NZ_CP022386.1|WP_095909429.1|344045_348335_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|375967
NZ_CP022386.1|WP_095909431.1|352426_353152_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP022386.1|WP_095909429.1|344045_348335_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	7.4e-64	211.2	63.7

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_002668348.1|356517_356937_-|DUF5606-domain-containg-protein	gnl|CDD|375774	pfam18347, DUF5606, Domain of unknown function (DUF5606). This is a domain of unknown function found at the N-terminal region of bacterial proteins.	5.29758e-18
NZ_CP022386.1|WP_095909425.1|338602_340606_+|excinuclease-ABC-subunit-UvrB	gnl|CDD|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP022386.1|WP_095909435.1|357610_358063_-|hemerythrin-domain-containing-protein	gnl|CDD|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	5.54525e-05
NZ_CP022386.1|WP_095909432.1|353207_354803_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.18369e-44
NZ_CP022386.1|WP_095909421.1|334537_335695_+|GDP-mannose-4,6-dehydratase	gnl|CDD|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP022386.1|WP_095909428.1|343228_343837_-|YigZ-family-protein	gnl|CDD|376491	pfam01205, UPF0029, Uncharacterized protein family UPF0029.	8.78595e-53
NZ_CP022386.1|WP_095911255.1|340587_341661_-|chorismate-synthase	gnl|CDD|376510	pfam01264, Chorismate_synt, Chorismate synthase.	0
NZ_CP022386.1|WP_095909424.1|337532_338606_+|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.12452e-171
NZ_CP022386.1|WP_095909433.1|354864_355473_-|dephospho-CoA-kinase	gnl|CDD|238980	cd02022, DPCK, Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.	6.74894e-55
NZ_CP022386.1|WP_095909434.1|355469_356399_-|YbbR-like-domain-containing-protein	gnl|CDD|377947	pfam07949, YbbR, YbbR-like protein. The members of this family are are all hypothetical bacterial proteins of unknown function, and are similar to the YbbR protein expressed by Bacillus subtilis. One member is annotated as an uncharacterized secreted protein, whereas another member is described as a hypothetical protein in the 5'region of the def gene of Thermus thermophilus, which encodes a deformylase, but no further information was found in either case. This region is found repeated up to four times in many members of this family.	0.00192155
NZ_CP022386.1|WP_002668472.1|356950_357547_-|peptide-deformylase	gnl|CDD|234668	PRK00150, def, peptide deformylase; Reviewed.	1.91048e-76
NZ_CP022386.1|WP_095909423.1|336295_337447_+|metallophosphoesterase	gnl|CDD|277368	cd07425, MPP_Shelphs, Shewanella-like phosphatases, metallophosphatase domain. This family includes bacterial, eukaryotic, and archeal proteins orthologous to the Shewanella cold-active protein-tyrosine phosphatase, CAPTPase. CAPTPase is an uncharacterized protein that belongs to the Shelph (Shewanella-like phosphatase) family of PPP (phosphoprotein phosphatases). The PPP family is one of two known protein phosphatase families specific for serine and threonine. In addition to Shelps, the PPP family also includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, PrpA/PrpB, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	2.4617e-41
NZ_CP022386.1|WP_002668400.1|351916_352294_-|ribonuclease-P	gnl|CDD|234989	PRK01903, rnpA, ribonuclease P protein component.	1.5081e-21
NZ_CP022386.1|WP_002668555.1|350625_351819_-|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl|CDD|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP022386.1|WP_095909430.1|349553_350561_-|ketoacyl-ACP-synthase-III	gnl|CDD|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	1.35647e-152
NZ_CP022386.1|WP_095909429.1|344045_348335_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl|CDD|375967	pfam18541, RuvC_III, RuvC endonuclease subdomain 3. Cas9 proteins are abundant across the bacterial kingdom, but vary widely in both sequence and size. All known Cas9 enzymes contain an HNH domain that cleaves the DNA strand complementary to the guide RNA sequence (target strand), and a RuvC nuclease domain required for cleaving the noncomplementary strand (non-target strand), yielding double-strand DNA breaks (DSBs). The crystal structures of type II-A and II-C Cas9 proteins highlight the features in Cas9 enzymes that support their function as RNA-guided endonucleases. Cas9 enzymes adopt a bilobed architecture composed of a nuclease lobe containing juxtaposed RuvC and HNH nuclease domains and a variable alpha-helical lobe likely to be involved in nucleic acid binding. The RuvC domain forms the structural core of the nuclease lobe, a six-stranded beta sheet surrounded by four alpha helices, with all three conserved subdomains (I, II, III) contributing catalytic residues to the active site.	1.03794e-57
NZ_CP022386.1|WP_095909431.1|352426_353152_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.41532e-62

Protein sequences

>NZ_CP022386.1|WP_095909429.1|344045_348335_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKRKHILGLDLGTTSIGFAHIVEDENKEKSEIKELGVRIVSLTTDEQSDFEKGKSITTNANRTLKHGARLNLDRYQQRRKYLIDLLQKANLITSSSILAENGKNTTHSTWQLRAKAVTERVEKEEFARILLAINKKRGYKSSRKVKTEDEGQAIDGMAIAKRLYDENLTPGQLSLQLLQQNKKLLPDFYRSDLQKEFDLVWNFQKQFYPDILTDSFYKELQGKGKDATSKAFSKKYHFDIAENKGSKESVRLQAYQWRVEAISKQLSKEEVAYVLTEINNNLNNASGYLGAISDRSKELYFNRQTVGQYLYAQLQENRHNSLKNKVFYRQDYLDEFERIWETQASFHKELTDELKKQIRDVVIFYQRKLKSQKGLISFCEFESKEIEIEKDGKTITKSIGARVVPKSSPLFQEFKIWQILNNVICKRKGIRKKKISAKTTQLDLLNESSQTIFSLDMECKQLLFDELNLKGDLKSDKVLKLLGYSPQEWEINYNQLEGNRTQKALYEAYLKIVEMEAHDVKNILQIKSAKDDWSLDESPLSASEIKEKVKDIFQALGICTKILYFDPLLPVKDFEEQDSYQLWHLLYSYESDDSTSGNETLYRILEKKYAFKREHARILANIALQDDYGNLSTKAIRKIYPYIKENQYSTACEKAGYKHSKLSLTKEELEARELKNIIPLLKKNALRNPVVEKILNQMINVVNALIEKNSERDAEGKITKYFHFDEIRIELARELKKNAQERYEMTQNINKAKSEHQKISEILQKEFGIKNPTKSDIIRYRLYQELEHNGYKELYTNAPIARDMLFSKNIEIEHIVPKARVFDDSFSNKTLTFHRINSDKGESTAFDYITSLNSEEELNQYLTRVENAYKTKSISLTKYKNLLKKASEIGDGFINRDLRDTQYIAKKAKEILFQVTKNVLSTSGSITDKLREDWGLVDVMKELNMPKYQSLGLTEVEERKEGNKVTVIKNWTKRNDHRHHAMDALTVAFTKPSYIQYLNHLNARKDENNKNYSVILAIEEKETIKVPTNNGKNKRVFIEPIPNFRQVAKKHLEEIFISHKAKNKVVTKNVNKPAGTDKQQIILTPRGQLHKETIYGKYQYYINKEEKVGVKFDKETITKVSNPLYREALLKRLQANGNDPKKAFTGKNALSKNPIYLDEAKTKTLPEKVNLTYLEEDFSIRKDISPDNFKDLKSIEKVIDQGVKRILIKRLQTYDNDPKKAFVDLEKNPIWLNKEKGIAIKRVTISGVSNAQPLHIGKDHLGKTILNKEGNKNPIDYVSTGNNHHVAIYRDKEGNLQEQIVSFFDAVVRAQQGLPIIDKTYKQAEGWQFLFTMKQNEMFVFPNATTGFNPAEIDLLDPKNKKLISPNLFRVQKIATKDYFFRHHLETNVETDNVLKNTTWKREGLSGLKDIVKVRINHLGDIVSIGEY
>NZ_CP022386.1|WP_095909428.1|343228_343837_-|YigZ-family-protein
MTDTYKTITQPVTDIIYKDKSSKFIGYLYPITTEEEVKMHLEAVKKEHFSARHWCYAYQLGKEQFIYRANDDGEPSGTAGLPIYRQIQSFELTNVLLIVVRYFGGIKLGVSGLITAYKTTAQLTLQEAEIEERTIDLTYQIVFDYKDMNKVMKIIKDRNLTIVSQTLELNCTLLIEVRKAEASYVEQLFEQLYEVTITPIEG
>NZ_CP022386.1|WP_095909427.1|342496_343105_-|hypothetical-protein
MIQTDKPISSSGYGIAIISAQLFHEQCKEHKIRSKKMLSYFDKNPYLFYEFAAKGAFIPISHIHSYYYQVFFTIDDNRQTPEEWDFVPTKETFCLEVKDGALWVVSFEQLEAWNYKDLEEFTAIETYYYLTYEGEKQIAYKAAKYPIANGKYKVNIIALRKKEVEKEEKFREGYAFLLQLEKVATLPNSDDASQLDFSELFA
>NZ_CP022386.1|WP_157909404.1|341775_342384_-|hypothetical-protein
MDTQVEDILDRILQSYPQTVFTKNIEFIKKTNANLEDVDTIQSIKTLAILLEVLGNAELALQTSSIIDKIEFTGDMLIWEKVRDVLILEYFIYQERKEFQKAKAIMDKMTLVFERGDEAQQRKSKRILDRVLNGSLLHTEEIENAIKRNDIKAEIHHHYLQYNILKYMKIRGGSEAYPIERLDPMIEEEKQFIAKHIDKALF
>NZ_CP022386.1|WP_095911255.1|340587_341661_-|chorismate-synthase
MAGNTFGHLFRLTTFGESHGEAIGGVIDGCPAGIALDFEEIQRELDRRRPGQSAIVTQRKEADKVQFLSGIFEGKTTGVPIGFIIANTQQHSQDYDHLRELYRPSHADYVYEQKYGLRDHRGGGRSSARETTVRVVAGAIAKQFLKGIKVTAYVSAVGELSLPEEDYGQLDFSQIEKNPVRCPDPVLAAQMESYIKEVRKEGDTVGGIVSCVIQGVPVGLGEPVFDRLHAELGKAMLSINAVKGFEYGGGFASTRKRGSQNNDIFLPDGTTRTNYSGGIQGGISNGMDIYFRVAFKPVATLMQEQETINRAGEVVQFQGKGRHDPCVVPRAVPIVEAMSALVLADYLLIHNAYKELS
>NZ_CP022386.1|WP_095909425.1|338602_340606_+|excinuclease-ABC-subunit-UvrB
MKFQLVSDFKPMGDQPAAIASLVNGINDQEKYQTLLGVTGSGKTFTIANVVEQVQVPTLVLAHNKTLAAQLYNEFKAFFPNNAVEYFVSYYDYYQPEAYIPVTGVYIEKDLSINEDIERMRLSTTSALLSGRRDVLVVASVSCLYGIGNPLEFQKNVISIEEGQTLTRTKFMHQLVQSLYARTTADFLHGNFRVKGDIIDIFPGYSETPIRVHFFGNEIELIESFDRETNKTIERLDKLNIYPANMFVTSPDVLQAAIRDIQDDLVKQIEFFQSVGKTLEAKRLEERTNFDLEMIRELGYCSGIENYSRYLDRRPPGSRPFCLIDYFPKDFLMVIDESHATVPQVRAMYGGDRSRKENLVEYGFRLPAAMDNRPLKFEEFEVLQNQVIYVSATPADYELQKCGGVYVEQVIRPTGLLDPKIEVRPSKNQIDDLLEEIQKCVEEDQRVLVTTLTKRMAEELTKYLTKMEVRCRYVHSDVDTLERIEIMQDLRKGLFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRSARSMTQTVGRAARNIDGRAIMYADKITDSMRVTIEETAYRREKQMNYNLTHGITPQPLHKKIENALSKSPITEFHYENTPKKKEHSPTKPMSRGELEKEIQQTRKLMEAASKELDFIQAAHYRDLLKELQEKLQESSL
>NZ_CP022386.1|WP_095909424.1|337532_338606_+|GDP-L-fucose-synthase
MNKNAKIYVAGHRGLVGSAIWKNLKNKGYTNLIGRTHTELDLRNTQEVNAFFEKEKPEYVFLAAAKVGGILANNTYRADFIYENLMIQNNVIHAAYENGVKKLLFLGSTCIYPKEAPQPMPEDCLLTSPLEYTNEPYAIAKIAGIKMCESYNLQYGTNFISVMPTNLYGPNDNFDLEKSHVLPAMIRKIHLAKALLENDWQTIKKDLNKRPIEGYITGESKQEDIILALAKYGIFKDKVVLWGTGTPLREFLWSEDMADACVFIMERINFKDTYTTDNKEIRNTHINIGTGSDLSIKALAELIREAIGYKGTIEFDSSKPDGTMKKLTDPTKLHNLGWKHTVSLEKGVKMMYEHYLK
>NZ_CP022386.1|WP_095909423.1|336295_337447_+|metallophosphoesterase
MYAAAMGLLTLGSNLSVNAQTKVHYSEKRLKADTSKADFDGPYIFYTQTEAVVKQIVEKNQQATLVSETFKNPIAGKKLTCYVDNKEHFSFKVQELLQNQPSVYQMPEKLIAISDIEGRYQEFKQFLIANKVMDKNYKWTFGKGHLVTVGDFFDRGLLVNQTLWLIYSLEEQAEKAGGKVHFILGNHDLMNMKNDFRYTRKKYLENAKLMGVEYYDLYKPNTELGRWLATKNILEKIGDYIFIHAGISKEVSDLNLGVEGINKFARNFYFDNVEDRAGVDPLRSVVYMRGKSPTWYRGYGKETIDKNEFAAIAKNMGAKKFVIGHTLHESVTYLMDKQVIDLDVLHAQGTTQGLLIENGQEYMVDIQGQKSAIKERAKEVDDD
>NZ_CP022386.1|WP_095909422.1|335705_336245_+|hypothetical-protein
MELTQKLRHIFISDLEKCSPLMEEDLKGLLTNSTIPYLEGKDETDVRAFCFEYDHDDMSISFYALGEKSEIISDICLLLTEREENHFPSDRYASQEEILEDLLYETSLEEAQIEDLLSEYRKEKLSIFTHWFIARWKNVTEQLNITIDAYFSKINAFYKTDLNSLEPISTEEIEEKYNT
>NZ_CP022386.1|WP_095909421.1|334537_335695_+|GDP-mannose-4,6-dehydratase
MPKKALITGITGQDGAYLAEYLLKKGYEVHGMKRRSSLFNTDRIDHLYQDPHLENRNLILHYGDLTDSMNITRLIQEVQPDEIYNLAAMSHVHVSFQTPEYVGNADGLGTLRILEAVRLLGLTEKTRIYQASTSELYGLVQEVPQSERTPFYPRSPYAVAKLYAYWITVNYREAYKMHASNGILFNHESPIRGETFVTRKVTRALSRVALGMQERFYMGNLSSQRDWGHAKDYIKAMYLILQQDTPSDYVIATGITTAIRDFIALAGKEIGLTIEFKGEGTEEKGYITAVDKAVFSEKVGEKYLPHIEEKIAKNEAVVLVDPQYFRPTEVDLLIGDPTKSQTVLGWKPQYDLKSLVEDMMRSDIKLFKRDAYLKEGGFTIMNYFE
>NZ_CP022386.1|WP_095909430.1|349553_350561_-|ketoacyl-ACP-synthase-III
MYNSTIIGTGYYVPENIVTNDDLSKLMDTSDEWIRERTGIEQRRFATRGKDTTTSMGVRAAERAIEKAKINKEDIDFLIFATLSPDYYFPGCGVLAQKELGLGTIGALDIRNQCSGFVYALSVADQFIKTGMYKNILVIASEMQSPALDLTTRGRNMAVLFGDGAGAVVLSRTTQEGKGILSSHLHSEGAYAEELAIVTPGVGKKWVTDLIKENDPEDTSYYPYMNGQFVFKNAVVRFSEVIMEGLKANNLTEGDIDLFIPHQANLRISQFIQQKFKLSDAQVFNNIQKYGNTTAASIGIALAEAVEQGRVKENDLLVLAAFGSGFTWGSVVIRM
>NZ_CP022386.1|WP_002668555.1|350625_351819_-|ADP-forming-succinate--CoA-ligase-subunit-beta
MNLHEYQGKEILSSFGVRVQRGIVATTADEAVKAAEKLTEQTGTQWYVVKAQIHAGGRGKGGGVKLAKNLEQVKEISSQIIGMHLVTPQTPKEGKKVHQVLIAEDVFYPGESEPKEYYMSILLNRAKGKNMIMYSTEGGMDIEAVAEKTPHLIFTEEIDPELGLLPFQARNVAFNLGLEGEAFKEMVKFVTSLYKAYITSDANLFEINPVLKTSDNKILAVDAKVTIDDNALFRHKDYAELRDTREERPIEVEAKAAGLNYVDLDGNVGCMVNGAGLAMATMDLIKQAGGEPANFLDVGGTADAARVETAFRIILKDPNVKAILVNIFGGIVRCDRVAQGIVDAYKNMGTDIKVPIIVRLQGTNAEIAKEIIDKSGLAVHSAIQFQEAADKVKEVLK
>NZ_CP022386.1|WP_002668400.1|351916_352294_-|ribonuclease-P
MVSLKEKRNTFPKAERLCNYHRVNKLFREAKVLKKYPLKLLYTPIEGSTQPTQLLISVPKRLMKKAVDRNRMKRLIRESYRHQKSLLSTERTYSLALLYMSKEELSYREIYALVGELLKELSTQD
>NZ_CP022386.1|WP_095909431.1|352426_353152_-|response-regulator-transcription-factor
MEAVNKKILLVEDDPNFGTVLKDYLSMSGFDVTLAKNGMEGFDKFRKDPYDMCILDVMMPYKDGFTLAKEIREKNEKVPIIFLTARTMREDVIKGYKSGADDYLNKPFDSEVLLMKIRAMLQRKSIDTVIDSKKFEFQIGDFFLNSKLRFLRYKDEEPLKLSPKENELLRLLALHENDLMPRELALNKIWKDDNYFTSRSMDVYIAKLRKYLKKDENVEIVNIHGEGFRLLTGKEEEEENA
>NZ_CP022386.1|WP_095909432.1|353207_354803_-|HAMP-domain-containing-histidine-kinase
MNKRSYIVTLILMPIALIGLISIQFYWVKGSIDNKEEAFTHSVKQALNSVSESVELKEINKYITRFIELKGKDSLGSLKSSQIRDLVFVQENKNTKETFTYKHQVLEEGYTVPSELFNLPKGDTTQIRNYVSRQTSRTFGPSKGLDGQRFSSTTIKEKTGRITSFDKAMFEELFREVSVKLSIENRITASQLEILIERELRNRGLNLDFEFAVYDKSLSVDKEKTSVASSRFNPSARNMYTIPLFRNQEGESHYELKVHFPDKQRYLLSSVIVMAIWVCIFTAIIIWAFAKTFIQMRTQKQINEIKTDFINNMTHEFKTPIATINLALDAMKNPVVMKDTEKMSFYLKMLRDENKRMHAHVENVLQISKLDKNQVEIEKEPLDAHELIDNAIAHVQLLIDDRGGKIKKHLHAENSDILANEMHFTNVIVNILENAIKYSPQAPDIDVFTEIAHNKLVIRIQDKGQGMSKAVLKKIFDKFYREHTGDLHNVKGHGLGLAYVKRIVKYHDGEVYAESEKGKGSTFVIKVPLII
>NZ_CP022386.1|WP_095909433.1|354864_355473_-|dephospho-CoA-kinase
MIATVGLTGGIGSGKTTIANLFALHFSIPIYIADTKAKELVANNKQLQQEIVTLLGEEAFVEGRYNTAFVAQEVFSNKDKLDKLNAIIHPYVQQDFLQWKQSQQAPYVIKEAAILFESGFYRDCDFIIMVTAPLEERIKRVMLRDKIDRETVEKRIKNQWNDEKKIELSTFVIENREIDKNLDKIEIIHSKIVKMTAENVRN
>NZ_CP022386.1|WP_095909434.1|355469_356399_-|YbbR-like-domain-containing-protein
MKLNRYFFSKRTIGILFCILLAALTWLVGKLSKEATQQYTIKLRYMEVPTERFVEMEASPTIKVKLRGVGFSLFKYTFSPPVFSLSVHKLKKVGKDKYVFTENLKQQLNRQYFPDVRIEEIQPDTIKIYLKKIKQKKVPVRLQFSGTLQEDYQVDSYKVFPDSVVVSGLAADLDTITGVYLQKKYKRNVTTSYSGEIRITDTPKLHYDTDKVTFSLQMVHVTEQEIKAKVQLIHQPFSVEVKLFPEEVPLLLTGNVETIRNLKPTDITIVADYNQRKDRYIPLEVRKKPASLNVNFTEQKEVEYLIIHE
>NZ_CP022386.1|WP_002668348.1|356517_356937_-|DUF5606-domain-containg-protein
MKLNQILTISGKPGLYQLQSRTRSGFLALSLLDQKRISIGLRNNVSLLSEIAIYTLEGEKPLEEVFKAIKEKENGQKTAVSHKATEDELEAYFFSVIPNYDEDKVYPSDIKKIIQWYNILIDKGFLEEEAPVASQEAEA
>NZ_CP022386.1|WP_002668472.1|356950_357547_-|peptide-deformylase
MILPIVAYGDPVLRKECMPIAKDYPELPKLIEDMYQTMYHSNGVGLAAPQVGLAIRLFVVDTEPFCENDDLSDAERDYLKGFKKAFINAKILKEEGEPWPFSEGCLSIPGISEDVLRKPTIVIEYQDEHFATHTETFSGLVARVIQHEYDHIEGILFTDHLSSFKKQLLKNKLNNISNGKVKVGYKMRFFETNKKRTR
>NZ_CP022386.1|WP_095909435.1|357610_358063_-|hemerythrin-domain-containing-protein
MKRNPNIVPLSKDHHFGLLHVWKIRQGLKKEIAPARIAQYVVFHWEHEQKAHFEEEEKYLFPYITNKLIDQALEEHHLLRDLIAQITTQPTAALLEEYATRLNDHIRYEERVLFPYMEENLSEEQLTEIGKNLSADPHTEEESYSDEFWQ

Crispr_ID: NZ_CP022386_4

• CRISPR_ID: NZ_CP022386_4
• CRISPR_location: 389287-389379
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP022386_4

Consensus_repeat	Method
TCATCTGTATAAACTTTAGGATGCGATAAA	CRISPRCasFinder

spacers of NZ_CP022386_4

>4.1|389317|33|NZ_CP022386|CRISPRCasFinder
CCAATACAACCAAACTTATATTTTAATTCATCG

CRISPR arrays and Neighbor proteins around NZ_CP022386_4

CRISPR arrays

The CRISPR arrays of NZ_CP022386_4

>merge|NZ_CP022386|4|389287-389379|CRISPRCasFinder
TCATCTGTATAAACTTTAGGATGCGATAAACCAATACAACCAAACTTATATTTTAATTCATCGTCATCTATATAAACTTTAGGATGCGATAAA

>NZ_CP022386|4|4|389287-389379|CRISPRCasFinder
TCATCTGTATAAACTTTAGGATGCGATAAA	CCAATACAACCAAACTTATATTTTAATTCATCG
TCATCTATATAAACTTTAGGATGCGATAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_002668457.1|399510_400245_-|LPS-export-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213185
NZ_CP022386.1|WP_095909460.1|394926_395694_-|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl|CDD|224182
NZ_CP022386.1|WP_095909458.1|391981_392617_-|endonuclease-III	unknown	unknown	gnl|CDD|223255
NZ_CP022386.1|WP_095909448.1|381489_382728_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911258.1|394174_394822_-|SCO-family-protein	unknown	unknown	gnl|CDD|239266
NZ_CP022386.1|WP_095909456.1|389878_390328_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909450.1|383800_384895_+|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl|CDD|376614
NZ_CP022386.1|WP_002668494.1|378868_379591_-|FadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225097
NZ_CP022386.1|WP_095909449.1|383006_383771_+|murein-L,D-transpeptidase-catalytic-domain-family-protein	unknown	unknown	gnl|CDD|379310
NZ_CP022386.1|WP_095909453.1|387623_388193_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909461.1|395743_397177_-|nitrite-reductase,-copper-containing	unknown	unknown	gnl|CDD|131429
NZ_CP022386.1|WP_095909447.1|379855_381277_+|PDZ-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_CP022386.1|WP_095909462.1|397495_398563_+|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|237363
NZ_CP022386.1|WP_095909451.1|384897_385674_+|hypothetical-protein	unknown	unknown	gnl|CDD|224495
NZ_CP022386.1|WP_095909463.1|398612_399458_-|transketolase	unknown	unknown	gnl|CDD|238970
NZ_CP022386.1|WP_095909452.1|386472_387363_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909457.1|391335_391896_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909459.1|392639_394070_-|L-serine-ammonia-lyase	unknown	unknown	gnl|CDD|273233
NZ_CP022386.1|WP_095909454.1|388543_388993_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911257.1|378093_378879_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225852

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_002668457.1|399510_400245_-|LPS-export-ABC-transporter-ATP-binding-protein	gnl|CDD|213185	cd03218, ABC_YhbG, ATP-binding cassette component of YhbG transport system. The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.	2.31451e-139
NZ_CP022386.1|WP_095909460.1|394926_395694_-|formylglycine-generating-enzyme-family-protein	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	5.00192e-40
NZ_CP022386.1|WP_095909458.1|391981_392617_-|endonuclease-III	gnl|CDD|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	1.86699e-81
NZ_CP022386.1|WP_095911258.1|394174_394822_-|SCO-family-protein	gnl|CDD|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	2.05341e-33
NZ_CP022386.1|WP_095909450.1|383800_384895_+|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl|CDD|376614	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3). This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.	1.1261e-41
NZ_CP022386.1|WP_002668494.1|378868_379591_-|FadR-family-transcriptional-regulator	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	6.80763e-38
NZ_CP022386.1|WP_095909461.1|395743_397177_-|nitrite-reductase,-copper-containing	gnl|CDD|131429	TIGR02376, Copper-containing_nitrite_reductase, nitrite reductase, copper-containing. This family consists of copper-type nitrite reductase. It reduces nitrite to nitric oxide, the first step in denitrification. [Central intermediary metabolism, Nitrogen metabolism].	8.24291e-117
NZ_CP022386.1|WP_095909447.1|379855_381277_+|PDZ-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	3.03127e-137
NZ_CP022386.1|WP_095909462.1|397495_398563_+|branched-chain-amino-acid-aminotransferase	gnl|CDD|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	2.39986e-157
NZ_CP022386.1|WP_095909451.1|384897_385674_+|hypothetical-protein	gnl|CDD|224495	COG1579, COG1579, Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only].	2.06166e-14
NZ_CP022386.1|WP_095909463.1|398612_399458_-|transketolase	gnl|CDD|238970	cd02012, TPP_TK, Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the pentose phosphate pathway and provides precursors for nucleotide, aromatic amino acid and vitamin biosynthesis. In addition, the enzyme plays a central role in the Calvin cycle in plants. Typically, TKs are homodimers. They require TPP and divalent cations, such as magnesium ions, for activity.	1.83825e-117
NZ_CP022386.1|WP_095909459.1|392639_394070_-|L-serine-ammonia-lyase	gnl|CDD|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP022386.1|WP_095909449.1|383006_383771_+|murein-L,D-transpeptidase-catalytic-domain-family-protein	gnl|CDD|379310	pfam13645, YkuD_2, L,D-transpeptidase catalytic domain. This family is related to pfam03734.	2.65567e-80
NZ_CP022386.1|WP_095911257.1|378093_378879_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	1.48316e-48

Protein sequences

>NZ_CP022386.1|WP_095909454.1|388543_388993_-|hypothetical-protein
MIAYYITIDIFGTELLIDEILKILGNKIKIDSIIHPNDMNKKGEKYDFGCISLSHPKVYIADDELVDYLSWLSDVIKEYFDIFYTLGMEEVWFYTNIYYTDSFLSLDLFDSDFFKQIASYKNKISISIPMNIYKETEQEIIEMLRERPY
>NZ_CP022386.1|WP_095909453.1|387623_388193_-|hypothetical-protein
MKKLLLIVMVAAHFVAFGQKKKKSIPPPPEKITKQKVQKSPYQRIFEDNRMLAFQWEMEVKDSIIIANEDRMIYKIYLEFHSDKEFSSYKKQPHISALKVIYSVEKGAKLDKNLTPRTHYFDLVDYPWISESVKIVGDNVELTNDETKEKQIFKIFLDKDKKNIIKLQDSKTKKEFFPTEDFYTPAVSI
>NZ_CP022386.1|WP_095909452.1|386472_387363_-|hypothetical-protein
MYKYIDFSPFGNSAIELEFKCNECHNTIKTEQFGLPHPNYMAEKASDSYVDREEFVICENCQKEFIIDINVGYADAYVSIIGLKEENEVIITEIPDYYMDEQINSFLYSENPYSNFIDEMHKLKELNKLSLNNNELEKTLKRQIYSSTITCLEDYLSTTLINNVLNDNILFRKFVETYENFKKEKFSLNQIFIKREQLESKVKEHLLGIIYHNLHIVKGIYETTFDIKFPDINEVMKIVINRHHMVHRNGKDKDGNEIILDINNVNDVIYKVEEFIKKINLLLTNNINKEDDEVPW
>NZ_CP022386.1|WP_095909451.1|384897_385674_+|hypothetical-protein
MTKKEVSVEDKLRTLYALQLIDCKIDELRNVRGELPLEVEDLEDEVAGLESRAERLVNDIDKINVDISTKKNLIEESKGLIKKYAEQQKNVRNNREFNAISKEIEFQELEIQLAEKHLKEFKAEIEQKKLSIAKIKDQLEERKKHLQHKKEELSSILEETQKDEETLLKKSLEISSQIEPRLLSAYQRIRNSVVNRLAIVAVERGASGGSFFVIPPQVQVEISTRKKIITDEHSGRILIDPDLAREEKEKMEEFFQAM
>NZ_CP022386.1|WP_095909450.1|383800_384895_+|Nif3-like-dinuclear-metal-center-hexameric-protein
MKIQDVIQYLETLAPLDYAESFDNVGLLVGNAQEPFRGALITLDTLEEVVEEAIQRDCNLIVSFHPIIFSGLKSLTGKTYVERAVIKAIEHHIAIYSLHTALDNSFWGVNARICDQLALSERKILLPQPHTIEQLITYVPSEHAQALREKLFEAGGGNIGNYSHCSFNLQGVGTYQGNQHSHPTIGERGVFHQEEETRISIIFPKHLRTKMLQALFTHHPYEEVAYEILSLENEHQHIGLGMIGLLPSPMEEKDFILYVKQRMQTSCIRHSPFLGKKIQKVAVLGGSGASAIGACLKAGCDAYITADVKYHEFFKAEGRILLADIGHYESEQFTKMLLWEQLTKKFPIFAFYLANTNTNPINYL
>NZ_CP022386.1|WP_095909449.1|383006_383771_+|murein-L,D-transpeptidase-catalytic-domain-family-protein
MKNFVYFCLISFCLASFSSYSQASKPISPKITEIIKDSLFAPHDNFEYAIKRLYIDIKGSEHNLDFKAFRYAYIGYQNMKLKNKLNEKRLLSIIDFTKDSDKKRFYTIDLEAKKILYYTYVAHGKKTGMSSSTYFSNENESHKSSLGFYVTGRTYNGDAGFSLKLYGDERNYNSNAYKRGIVIHTADYMNEDFFQKNGRYGRSLGCPVLPTDIYKQVIETIKEGTMVFAYYTNKRYLASSKYLKVSNLTKNNTF
>NZ_CP022386.1|WP_095909448.1|381489_382728_+|hypothetical-protein
MNTRKDIQWAFLYFIITVLLGFSLRMSYVTDAFFNVRHVTHSHSHVGLLGWIYTILTSLICQYFLKEEDRKPYRILFLCTQVTILGMLFTFPFGGYYLYSIIFSSLFVLCTYAFSIFFLKRSKKFVHLRFTLSKSVEPVCERPLSLRFVRWGIYFLVVSSIGIWLLPVAIVKTGKGDWYNSALYFFLHFQYNGWFLAVILSLLVGEIEHKSLLISKQLYKAFYCFILGTIGSVTLSWVGFFDHPLLYIIGNISGFLLLISVFEIYKAYNQLEKPAFLMKAFLLLWAIKTLLMFLGSFPWIAQVILPNREFIISYLHFTFLGVIAFGVLHFLSRNLYIRFPWWSLSLYTTAFIGTETLITYKGIAIYAQWFLPNNYPILLVVFSTLFFIAVGNWCYIIFRKTHTSSDQIFSKK
>NZ_CP022386.1|WP_095909447.1|379855_381277_+|PDZ-domain-containing-protein
MKKYFTSVISAIMGGAIALGGYHFITKNQENSTFSFSSQGDSTHVAQTNFRQVANFNFDENSFINASKKTVNSVVHVKNMTIAPEITSIFDLFSGNTPQQGGKERLAGTGSGVIISPDGYIVTNNHVINGASSVQVTLNNNQTYKAEIIGSDSSSDIALLKIKAPEKLPFLSFADSDNTQIGEWVLAVGNPFNLTSTVTAGIISAKARNLGNQYNGKIESYIQTDAAVNSGNSGGALVNLNGDLIGINTAIASANTGTFVGYSFAVPSNIAKKVVEDLIEYGNVQRGVLGIAGTELNSETAEKLKTKQTEGFYIDSVEDGSGAEKAGIKKGDIITQMDNIKIRSFSDLSGHINTKRPNDNVNIVVLRDGKEKEITVKLQKNDSFIANDLGIIIKNLSDKDKKDFKLKEGVKITKTSPLYAENGINLDGKVLISINGKEVKDIDSAKSILENSKSQRYAIIVQNKNGEKERYFL
>NZ_CP022386.1|WP_002668494.1|378868_379591_-|FadR-family-transcriptional-regulator
MKPLKEKTTASENDSLVDRVEKHIIEYIKENALKAGDALPKELEFAETLGVSRTAIREAMLRLRTLGLVESRKHRGMVILEPDLVHNFEKMLDPALVDVGRLSNLFELRLMLEVGMADFVFARKTPRQLKDLEDIVKNSEEQRCDSFNFSIEEERQFHGKLYEMAGNDILKKFQDVFMPIFQYVHDLNRYQAAYILPEGGKQVTHRDLLEELKQGTPFSFRELMREHLNAHYIKVLGISY
>NZ_CP022386.1|WP_095911257.1|378093_378879_+|class-I-SAM-dependent-methyltransferase
MLITLWAKAEERHYSPPFLIDKKAEEMLPLIDYDFSKFSRSKFSQAGVCLRASLIDKETQTFLSIHPDAVVIQLGAGLDARYERLGCPEVTHWYELDLPEVIQLRKDFFQENDKRSFIALSLFDMEWVEQIKAHTKPILILIEGVLMYFDPEEVKAFFLSLCQRLPKATVLFDMLAYSLVGHAKNHDSLSTMDKKQRPEFKWSERDSHTLEQWHPALHVEREYFMSDYNRGRYPFIFRMLYKIPYFYKRFNQRVVVLGISN
>NZ_CP022386.1|WP_095909456.1|389878_390328_-|hypothetical-protein
MIAYYITIEIFGTELLIDEILKILGNKIKIDSIIHPNDMNKKGEKYGFGCISLSHPKVYIADDELVDYLSWLSDVIKEYFDIFYTLGMEEVWFYTNIYYTDSFLSLDLFDSDFFKQIASYKNKISISIPMNIYKETEQKIIKKLRNRPY
>NZ_CP022386.1|WP_095909457.1|391335_391896_-|hypothetical-protein
MNKFLFGNKNNRQIWIIFIVTNLLYSLIIFMSIPHLQKLSQGLPILDIRSGGYTLEEVQALYTALGSEGRSYYLFPQLFFDIFYPGLFAVTYTWIIIRLLQQLSIQNKWLKGLCYLPLITSFFDYSENISIFITLKSYPELSPTLVQLGSVCTFLKNISGMMTFSVMIVLFLVWVVRKLRQNKSSN
>NZ_CP022386.1|WP_095909458.1|391981_392617_-|endonuclease-III
MNKKEKLHFITETLEELYPDPPIPLDHKDPYTLLIAVLLSAQCTDARVNQITPLLFAKADNPYDMIKLTQEEIQEIIRPVGLSPMKSHGIYHLSHILIDKYGGEVPQSFEALEALPSVGHKTASVVMSTAFGVPAFPVDTHIHRMLERWEISNGSTVVQSEKDAKKFFPKSKWNKLHLQIIYYARAYSPARNWDITKDIITSGIKTAKKKK
>NZ_CP022386.1|WP_095909459.1|392639_394070_-|L-serine-ammonia-lyase
MEYVSVFEMLKIGVGPSSSHTLGPWRAAEAFLKELRQRQILEKVQHVRVDLYGSLSLTGKGHATDLAAMLGLSGTDPEYIPVDSISTIISQIGKDKKLHLAGERFIDFDPATDVVFNKKFLPFHANGITFTATGEAIEDYASTFYSIGGGFIVKEKSEEGAAEKKEEQRSFPYEFESAKELLAHCQREEKNISDIIFEDEKILREEAKIHSELLRIWHTMIECAYIGCHTEGTLPGGLNVRRRAFDIHKKLMGEHLPYTNFEGWLGAIRQKKVDFREILKWVTCFSLAVNEVNASLGRVVTAPTNGSSGVIPAVLLYYLAIDNPQAGDREIERFLLTSGIIGSLFKKGATISAAMGGCQAEIGVSSAMAAAGLCELWGGTPEQVMIAAEIAMEHHLGLTCDPIGGLVQIPCIERNAMGAIKAINAAELALDTDPKNAKVPLDKVIQTMWQTAQDMNTKYKETSEAGLAVAVSMADC
>NZ_CP022386.1|WP_095911258.1|394174_394822_-|SCO-family-protein
MAMGVICLQACKNNTTDTAKEAETPSETVENTATKSQKEEGGATEISDLSIYNLPDTWTTQNGNQVQWKDFQGNVLVVVMIYTSCKAACPILIADMREIRKTVEASEAPHKEKVKYILVSIDPKVDTPEHLKKFAQESHMDDDQWVFLRSDEEKTREFAAVLAVNYKQISPVDFSHSNIISVFNTKGELAAQQEGLGIDRSSIVQQIKEQLEKIK
>NZ_CP022386.1|WP_095909460.1|394926_395694_-|formylglycine-generating-enzyme-family-protein
MKKRLLVCLLFLLEGIYAQAPTPMVEIKGGSYIPMYGVKEGQKKTKAVRVASFFFDVYPVTNAQYRDFLEKNPQWQRSKIKGIFAQKSYLVAWKSDLDFSPLDPEAPVTNVSWFAAKKYCECQGKRLPTIDEWEYAARADETSADARKKKSYSDYITHWLQTPNTYANKIGSTQKNYWGVYDMHGLVWEWVSDFNSVFFSGEARKDNFGDDGLFCGGSALNATDLTNYGAFMRYSLRGSLKANYTTKNLGFRCAK
>NZ_CP022386.1|WP_095909461.1|395743_397177_-|nitrite-reductase,-copper-containing
MKKYTQKLTILLALSLLVGACGGSEPEKTTTPIPTTDIPVEGEAVVAELTSPPHVPKPVGTRKAMKLKVDLEIIEKEGEIMDGTKYLFWTFGGTVPGSFIRTRVGDEVEFTLKNHQDNKLPHNIDLHAVTGPGGGAEASLVAPGQQRTFSFKCLNPGLYVYHCAQAPVPLHIANGMYGLILVEPEGGLPPVDKEYYVMQGDFYTDGAYGAGGTQAFNQDKALAEKPDYVLFNGKVGSLTQDGALTANPGETVRLFVGNGGPNMVSSFHVIGEIFDRVHVEGGKLTNENVQTTLIPAGGAAIVEFKVDVPGSYVLVDHSIFRAFNKGALGLLVAKGEENRKIYGKNEPKPYVSDVTIAVTPKEDVIVNKTKEQQIADGKVIYTKTCVACHQAQGQGLEGAFPPLAKSDFLNADVDRAIDIVLHGKQGEVTVNGKKYNNVMTPQPLSVQEVADVLTYVYNTWDNSKKVVTPEMVQKIKK
>NZ_CP022386.1|WP_095909462.1|397495_398563_+|branched-chain-amino-acid-aminotransferase
MDTTNLPISIEKVAKSRLSEVDFSKLNFGQIFSDHMFICDYKNGQWQDARIVPYGPFSVEPSLSVFHYGQTIFEGMKAYKDDRGEVFLFRPTENYARMNKSCKRMSMPEFPEELFDKALKTLVDLDRLWIQPGLGNALYLRPFMIATSAGVQANPSTEYRFMIITSPVQSYYKGGELKVKIADHYSRAANGGVGFAKTGGNYAGQFYPTALAKEEGYQQIIWTDDATHQKLEECGTMNVVIRIGDTLISPPPTERILDGVTRKSVFAVAEKLGIAIESRSITVTEVLEVASKGTLKEIFGCGTAAVISPVNAFSYEGKEYRLPDLEDSYAKRIKEFLLNIQYNKSEDPFGWRVRV
>NZ_CP022386.1|WP_095909463.1|398612_399458_-|transketolase
MSDIQQLTDLTTQVRRDILRMVHGVSSGHPGGSLGCAEFLVCLYNEVMDIKLPFTMDGKGEDLFFLSNGHISPVFYSVLARRGFFPVSELSTFRKLDTRLQGHPTPCEGLEGIRIASGSLGQGLSVAIGAALAKKLNGDSHLVYTLHGDGELQEGQIWEGAMYAAGKGVDNLIATVDYNGKQIDGPTDKVLPLGDLKAKFEAFGWSVVTIEKGNDIAAILEGLKVAKALTGKGKPVCILLHTEMGHGVDFMMGTHAWHGKAPNDEQLAKALAQNPETLGDY
>NZ_CP022386.1|WP_002668457.1|399510_400245_-|LPS-export-ABC-transporter-ATP-binding-protein
MKTLRAENIVKEYKGRRVVKGISLEVKQGEIIGLLGPNGAGKTTSFYMIVGFIKPNAGHIYLNNTEITKFPMYKRAQHGIGYLAQEPSVFRKMSIEDNILSVLQLTKLSKKEQIHKMESLIDEFNLGHIRKNRGDLLSGGERRRTEIARALATSPDFILLDEPFAGVDPIAVEDIQNIVFQLKNKNIGILITDHRVEVTLPATDRTYLMYEGGILKAGLPEELAYDPMVREVYLGNNFELKKRN

Crispr_ID: NZ_CP022386_5

• CRISPR_ID: NZ_CP022386_5
• CRISPR_location: 568893-569000
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP022386_5

Consensus_repeat	Method
AAAAAGAAAAAGAGAAAAATCCTA	CRISPRCasFinder

spacers of NZ_CP022386_5

>5.1|568917|60|NZ_CP022386|CRISPRCasFinder
AAAAACATTCCACTACTATATACGAATATGATACCTTAGGAAATCTTATTCGTATTACAG

CRISPR arrays and Neighbor proteins around NZ_CP022386_5

CRISPR arrays

The CRISPR arrays of NZ_CP022386_5

>merge|NZ_CP022386|5|568893-569000|CRISPRCasFinder
AAAAAGAAAAAGAGAAAAATCCTAAAAAACATTCCACTACTATATACGAATATGATACCTTAGGAAATCTTATTCGTATTACAGAAAAAGAAAAAGGAGAAAAATCCT

>NZ_CP022386|5|5|568893-569000|CRISPRCasFinder
AAAAAGAAAAAGAGAAAAATCCTA	AAAAACATTCCACTACTATATACGAATATGATACCTTAGGAAATCTTATTCGTATTACAG
AAAAAGAAAAAGGAGAAAAATCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_040360252.1|562217_562655_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909575.1|560829_561474_-|phosphoribosylanthranilate-isomerase	unknown	unknown	gnl|CDD|238237
NZ_CP022386.1|WP_095909576.1|561473_562202_-|indole-3-glycerol-phosphate-synthase	unknown	unknown	gnl|CDD|234710
NZ_CP022386.1|WP_095909572.1|555623_558530_-|serine-hydrolase	unknown	unknown	gnl|CDD|366376
NZ_CP022386.1|WP_095911265.1|581538_582660_+|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|273213
NZ_CP022386.1|WP_095909573.1|558878_559640_-|tryptophan-synthase-subunit-alpha	unknown	unknown	gnl|CDD|237285
NZ_CP022386.1|WP_095909590.1|580455_581346_-|agmatinase	unknown	unknown	gnl|CDD|212539
NZ_CP022386.1|WP_095909586.1|573830_574346_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240037
NZ_CP022386.1|WP_095909578.1|564309_565590_-|anthranilate-synthase-component-I-family-protein	unknown	unknown	gnl|CDD|223225
NZ_CP022386.1|WP_095909580.1|567283_568294_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909589.1|577643_580379_-|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl|CDD|378929
NZ_CP022386.1|WP_095909582.1|569491_570817_+|ATPase	unknown	unknown	unknown
NZ_CP022386.1|WP_095909577.1|562669_564313_-|anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|237764
NZ_CP022386.1|WP_095909583.1|570831_572238_+|ATPase	unknown	unknown	unknown
NZ_CP022386.1|WP_095909587.1|574489_576031_+|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl|CDD|223679
NZ_CP022386.1|WP_095909585.1|573474_573834_-|DUF2809-domain-containing-protein	unknown	unknown	gnl|CDD|378530
NZ_CP022386.1|WP_095909579.1|565812_567186_+|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NZ_CP022386.1|WP_095909588.1|576043_577567_-|lipase	unknown	unknown	gnl|CDD|238863
NZ_CP022386.1|WP_095909574.1|559632_560820_-|tryptophan-synthase-subunit-beta	unknown	unknown	gnl|CDD|235288
NZ_CP022386.1|WP_095909584.1|572252_573449_+|RHS-repeat-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_095909573.1|558878_559640_-|tryptophan-synthase-subunit-alpha	gnl|CDD|237285	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional.	1.37652e-97
NZ_CP022386.1|WP_095909589.1|577643_580379_-|PD-(D/E)XK-nuclease-family-protein	gnl|CDD|378929	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	5.4912e-16
NZ_CP022386.1|WP_095909576.1|561473_562202_-|indole-3-glycerol-phosphate-synthase	gnl|CDD|234710	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC.	1.17045e-95
NZ_CP022386.1|WP_095909572.1|555623_558530_-|serine-hydrolase	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	7.6504e-85
NZ_CP022386.1|WP_095911265.1|581538_582660_+|DNA-polymerase-III-subunit-delta'	gnl|CDD|273213	TIGR00678, DNA_polymerase_III_subunit_delta', DNA polymerase III, delta' subunit. This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair].	4.56684e-47
NZ_CP022386.1|WP_095909590.1|580455_581346_-|agmatinase	gnl|CDD|212539	cd11593, Agmatinase-like_2, Agmatinase and related proteins. This family includes known and predicted bacterial and archaeal agmatinase (agmatine ureohydrolase; AUH; SpeB; EC=3.5.3.11), a binuclear manganese metalloenzyme that belongs to the ureohydrolase superfamily. It is a key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield urea and putrescine, the precursor for biosynthesis of higher polyamines, spermidine, and spermine. As compared to E. coli where two paths to putrescine exist, via decarboxylation of an amino acid, ornithine or arginine, a single path is found in Bacillus subtilis, where polyamine synthesis starts with agmatine; the speE and speB encode spermidine synthase and agmatinase, respectively. The level of agmatinase synthesis is very low, allowing strict control on the synthesis of putrescine and therefore, of all polyamines, consistent with polyamine levels in the cell. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	1.36089e-107
NZ_CP022386.1|WP_095909578.1|564309_565590_-|anthranilate-synthase-component-I-family-protein	gnl|CDD|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	2.74907e-141
NZ_CP022386.1|WP_095909575.1|560829_561474_-|phosphoribosylanthranilate-isomerase	gnl|CDD|238237	cd00405, PRAI, Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric, monofunctional and thermolabile, but in some thermophile organisms PRAI is dimeric for reasons of stability and in others it is fused to other components of the tryptophan biosynthesis pathway to form multifunctional enzymes.	4.50194e-69
NZ_CP022386.1|WP_095909577.1|562669_564313_-|anthranilate-phosphoribosyltransferase	gnl|CDD|237764	PRK14607, PRK14607, bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase.	1.72563e-175
NZ_CP022386.1|WP_095909586.1|573830_574346_-|NUDIX-domain-containing-protein	gnl|CDD|240037	cd04681, Nudix_Hydrolase_22, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.39488e-43
NZ_CP022386.1|WP_095909587.1|574489_576031_+|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl|CDD|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP022386.1|WP_095909585.1|573474_573834_-|DUF2809-domain-containing-protein	gnl|CDD|378530	pfam10990, DUF2809, Protein of unknown function (DUF2809). Some members in this family of proteins are annotated as yjgA however currently no function for the protein is known.	1.91384e-21
NZ_CP022386.1|WP_095909579.1|565812_567186_+|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP022386.1|WP_095909588.1|576043_577567_-|lipase	gnl|CDD|238863	cd01825, SGNH_hydrolase_peri1, SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.11482e-29
NZ_CP022386.1|WP_095909574.1|559632_560820_-|tryptophan-synthase-subunit-beta	gnl|CDD|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0

Protein sequences

>NZ_CP022386.1|WP_095909580.1|567283_568294_+|hypothetical-protein
MKNYLLPFLFLFSIVIWGKNDPLPRKNRKTHKTIGDFFGKVKSLSSISCKVINDYKGDIIRTTRENYDHEYYYLFDEKGNITQTNKYDNSNKLIEEKKFLYSYNENDLLIKELYYKNNDLIGSYTYKYDKNANKIEETYEDTQKNYKYIRKYKYDDKNRLIFVKEKNTDREDTLNIFKRTYKDDLLMEEYYGEKNYSYTHTYFYENKKLKTKKEESSSFEGCYFTNTETIYTHNDKELPISCDVYISHKLQNNITYEYDEKGKEIKRVYTFPDDSQYNSYVTYQYDKKGNLIEENNSRLSEKIIYFYDEHNNWIKQEVYYNDKLSHIYERAFTYYE
>NZ_CP022386.1|WP_095909579.1|565812_567186_+|DNA-repair-protein-RadA
MAKTKTAFFCQNCGAQYSKWQGQCYACKEWNTIVEEVIQKEEKHQWKKDDESDTPRSKKTNKYIPLHEITTEKEMRLDSGDQELNNVLGGGIVPGSVVLIGGEPGIGKSTLLLQIAMRMPYKTLYVSGEESQKQIKMRGERITNARNNCYILTETKTQNIFQQIKELDPEILIIDSIQTLHSDYIEASAGSISQIRECTAELIKYAKLTGVPVIIVGHITKDGTIAGPKILEHMVDTVLQFEGDRNHVFRILRALKNRFGSTSELGIYEMLSTGLREVSNPSEVLLSKTDENSSGTAIVATIEGMRPLMIEIQALVSSAVYGTPQRSTTGFNAKRLNMLLAVLEKRAGFRLGSKDVFLNITGGISVDDPSTDLGVAMAILSSNEDVAIPKTFCFAAEVGLGGEIRPVQRVEQRISEAEKLGFDTIFISKYCKLTAGKRNINVITYAKVEEVIAHLFG
>NZ_CP022386.1|WP_095909578.1|564309_565590_-|anthranilate-synthase-component-I-family-protein
MFLTAPPLFYYTFIKERYKNSYLAEDVNQVIIGIDCDYLDAYKYSYTSLEQYHQRQKSIAPFAGLFGVFSYETIHFFEQIPEKSQKQYDFPAFVFANAKAYLHYSKVSKVYSFYGDEQQYFHFLEEATVQENPTGPEVFYQLHTDLAQERAHFYQMVEKAKEYIRSGDIFQVVLSEQLSLESNLDSLDFYRYLSQANPSPYMFHFPTPYGEVVGSSPEILVDITGSQIHIAPIAGSRPRGKDANEDLRLEQELLADPKECAEHRMLVDLARNDIGKFAQKGSVVVKDMMQILRYEHIMHIESHVYGDKRTEVSPFEVISIVFPAGTLSGAPKIRAMEIINELESFRRNVYGGGIGFLHFNGNVQLAIVIRSAFFEKANAENEQVSKVFIQAGAGIVYDSVSEKEYDEICHKRASVLNVFTKNCKEK
>NZ_CP022386.1|WP_095909577.1|562669_564313_-|anthranilate-phosphoribosyltransferase
MILLIDNYDSFVFNVAQYLQELTEEEVKTVRNDAITWEEITALNPSRIVLSPGPKHPKDSGICLEILQKNTTIPVLGICLGHQAFGMVNGAEIKRMEMPLHGKTSALRVTDDNTLLFRGLPKQFQVMRYHSLYVGKEQLPENIRITALSDDDIIMALEHKEKPIYSIQFHPESFFTEYGKHIIKNFITYTQKLQPSVADDHAQEKARANEVFKTALKKLQENIPLTDGDFKEICEVIHTKQYDIVQLGALLVLISEKSLYPESLTAFVRNILAYSTTFADESPMIDLCGTGGDGLKTINISTTVAFIVAAMGVKVAKHGNRSVTSQSGSSDVLGQLGIPLENNLLTQLEHLQKEHLAFFHAPFFHPLVGEVKEVRQRLGIRTVFNVLGPLLHPNAKLKYQLVGLYHEPVQRLYAETLQLLGRKHALVVRGNDGLDEITLCDETKIVEVKDGKILEYTIAPEMFGFKRAFHADIQGGTPEENAEILLRTLKGEEQSPKSDIVILNAMFALYTADFVKHPADAKPLIQEAIRSGKVYEHYLKMINANKE
>NZ_CP022386.1|WP_040360252.1|562217_562655_-|hypothetical-protein
MRQKLLKYVLFIMAIFVTDAVFLFLSMKDYKDSMSSSCLECSFWKDIFVFLLIGMGVLAILLTILFRIVKKRGYLYGLILISLLSIFYSIDYMLFVDRVAAWSTYSLKETWITIFWDSYRYFPMLMLIYVLLTNRLIKEIESINN
>NZ_CP022386.1|WP_095909576.1|561473_562202_-|indole-3-glycerol-phosphate-synthase
MDILSQIKQQRDLQLQRELASVARPSFHKALSQEGIRIIGEIKRASPSKGQIALENFDLLKQATHYVEHGVAAFSILTEEAYFKGDNTFIPQVVEAFPKVPILRKDFIYTPFQVAQAKFLGASAILLIVRMLSDEQLQALHALAYDLQMDVLVEVHDEAELQRALRIPQLKILGINNRNLNTFEVSLQTTERLLSLISEEQRAPLLVVSESGYLSKEDLHYAETLGVDALLIGEALMKGLLF
>NZ_CP022386.1|WP_095909575.1|560829_561474_-|phosphoribosylanthranilate-isomerase
MEKTALKICGIRSLEEIQDLKNLPIDYFGCIFAPRSPRCVSLALAKEITEIAHSEGKQTVGVFVNASLEQIADTVNLTGIDVVQLHGEESPDICKMLTTKGITVWKAFSIKDKLLPMEDYLPYMDLPLLDTKGVSEGGNGLVFNWQLLERLTPYSFILAGGISAENVQKALSYQPAIIDVNSKVEQDNRKSRQLIEKLIKEMEKYRRGIEKYNK
>NZ_CP022386.1|WP_095909574.1|559632_560820_-|tryptophan-synthase-subunit-beta
MTNKAYFGNFGGQYVPETAMFALIELEKEYEKAKNDPCFQAELEDLLKNYVGRPTPLYYAKNLSAHYGHDIFLKREDLNHTGAHKINNALGQVLLAKRMGKKKVIAETGAGQHGVATATAAALLGLECEVYMGAVDMERQQLNVFRMELLGAKVVAIEDGLKTLKEATTAAIQSWVAEIETVFYVIGSVVGPHPYPTIVRDFQSIIGREARKQLATQDRHADHVIACVGGGSNAIGIFAGFLDDPATQLYGVEAGGEGIDTDRHAATLTLGREGIIHGMKTYVLQDKYGQISPVHSISAGLDYPGIGPEHAHLFQTKRAHYAPITDTEAMEALLLTTRKEGIIPAIESAHALAYLSKLCPTLPKDKKQTIVVNVSGRGDKDMHTVFSILKGEKYE
>NZ_CP022386.1|WP_095909573.1|558878_559640_-|tryptophan-synthase-subunit-alpha
MNNNSINAVFAAKEKVNIGYIVAGYPNVDFTKAFLSQLDRTAIDILEIGIPYSDPLADGKLISQASFAASQAGVTTDTVFDLLSSVKGQVHKPLVFLVYYNLIFAYGIDAFLEKCVAVGIRGLIIPDLPYEEAQELVEKLRAHHIAFIPLVSVTSQGRIAPIVSLGEGFVYAIGSLGVTGSKQVDLPRLKEFITQVRAQTSLPVSLGFGIKTHADVEQMRQYADGVIVGTSIVALTSSGDLDQTITQINTLFK
>NZ_CP022386.1|WP_095909572.1|555623_558530_-|serine-hydrolase
MRFFTLLLFIPIFSFSQNIDPLRTKDEQAQTRWVDSIYKTMSLEQKIGQLFMVQAFSSHTAKQQKPIKELVKKYHIGGIIFSKGSPVAQAKLTNEFQEAAQVPLMIAMDAEWGLAMRLDSVYAFPWNMTLGALKDNALVEQAGKRIAQHCKRLGVHIDFAPDIDINTNPQNPIIGNRSFGESKFNVAQKGVAFTKGMQSVGVLACGKHFPGHGDTEKDSHKTLPTVSFSRERLESTEFFPFQKLIGAGVASLMVGHLNVPALDEGKPASISYKIVSGLIKQQLGFQGLIFSDALGMKGVADYAESSQVDLQAFLAGNDVLLMSSDPIKGIETLKNAYSAGTINEYRLAHSVKKILKAKYWAGLNKYKPVALTNLTKDLNTKEDDLLTEKIYEKAITLLQNAKNVLPLKNLDTKKTAYIKFGDDSGWEFFKNLRYYQDVVQLKSGSWESLKKEMAPYDRIIIGLHRSNASPWADYKFNTQELALLQKIVGEKKEVILTVFTKPYALLDVPDLSPFAAVVVAYQNAPFAQQKAAQLIYGAIPFEGVLPVTAHKGILFGRNLPTKPLNRLAYGLAENAGLNSANFYKIDSIVTDAIQKQMTPSAQVLVARNGVVVYQKSFGRCTYDKNAEQVTNNTLYDLASLTKILATVPELIDLYDKQKIKLNASLATLLPMLSGTNKADITVKEALSHYGQLQAWLPFYRKTIDSKTKVLSTDIYNATLTPKYPTQVAENIFIKENYRDTILQSIAQSDLIKQKKYLYSDLSYYLFQKYIEMTKGKPLNEAVEKDFYQSMGAYQLTFLPLKHFPKEQIAPSEDDKSFRQQLLRGYVNDQGAAMLGGVAGHAGLFGTANDVAKMMQLFLQKGYYGGVRYFSANAFDAFNKSYFISERNRRALGFDKPQLPGQGGYTCGCVSPESFGHTGFTGTLAWADPTTQTIYVFLSNRTFPTSDNKKLITENIRAKIQKVVQESLM
>NZ_CP022386.1|WP_095909582.1|569491_570817_+|ATPase
MKHLLIPFLFITTVIVAQNTANKVEKYKIDSDLAYPFEKPLLGKVKKVHTAHYSTVVTVLKDTIKREHFVENYTYGFDERGNEIEFIKYDKEGNIWNKEIKKYNEKDRLLYSKETKILGEDETYIEENSYSYNDKGFLIEEKSYEEDPDTGISHRRELYKYNNDQKLIENSYYSNDSLKRQVLYWYDNKGNLLRKLFYLDNKPYTDTKFEYNHIGNLIKKTENYIKTDYKHVKQYEYDAKNRLILFTKEDDDTKEIILKIIYKDDLLIEIYDNRDDEEVHIFYSYKNKKLINKVISKSFFNGCYYDYIKEKILYDEKGRIKKSFDYKQNKIKKTYTYYYDNKDRVIKTELLYTGDKKEYWIDNYDTIGNLIETIYKNDDYRDKDSYTYDNNNNLLSKITYKGNKAIEKTFYTYDKYQNIIKIEKYNNGKNYIYERTFTYYE
>NZ_CP022386.1|WP_095909583.1|570831_572238_+|ATPase
MKHFLIPFLFISTAVFAQNTANKVERYKINPAINDEFKKPLLGKVKTMHTAHYFIEYNKYDTIKKELFDNNYTYGFDKEGREILFIEYDMHGNISSKYERRYNEKDSLTYLRKFIWGENFGTYIEEKSYFYNPLGLLQELKGYSLKESDPLFIYRELYKYNDKQQLLESHYYSNDTLTETTIYSYNNKGKLIKKLDYLKGKLDSEYKLEYDERGNLIKKDYHFTQFSISQKSITKYQYDDQNRLILATENIDGDENILIKNIYKDNLPIEIYEKNRSEDEIHIFYHYKENQLIEEEKYTRFFNGHYYSTTKEKIQYDEKCRIKKFYDYEEEKIVRTYTHYYDDKDRIIKTELLYSNNKKEYWTNSYDMTNNLIKTIYKNNKEADKDIYRYDKNNNLLSKIIYKGNKEVYKVLYTYDKNNNLLSKTTYKGNKAIEKTFYTYDKYQNIIKIEKQYNGTTDIYERTFTYYE
>NZ_CP022386.1|WP_095909584.1|572252_573449_+|RHS-repeat-protein
MKYFLFTLLFYFSSCFYVSLLAQEDDPNRYREEHLRNLGITPQGKVKSVEKFIYHYENRNGKEVKIFPKNAKVERMPVHSRYTFDKKGNIIEFYNYHTDGKLFQKIFYQYNGDNLLTKADEYKYIEENNPQHTEEEIFYEGKVMISKKYKIDGNLFEIRMLFDKNKRKKAISEYRNNTLINKNKYSYNSKGNITYEKNKSMSLLGDEAYDTWYTYTKDGTLLAEKKECYSIFCFYTTYQYLANDEVYEETTYTTPLSDEKDVSNKKTKYYIYDSKGAIVEIQTYKGEDFRSYHCMENDKEVETYSYFLEGEVIKTLFSYNKDNQLIKEENFNLLTGDFTSGTYYMYDEKGNLLQIDDGQIPSPNRTIYHYDKFNNCTEEIYYKNNKRVAIVERIFNYY
>NZ_CP022386.1|WP_095909585.1|573474_573834_-|DUF2809-domain-containing-protein
MKFNSKYFFAALIIFLVEVAIATVFKSVPFVRAYLGDILVVILIYCFIRAFFHIKNTKKLLIGIFCFAVFVEILQYFKLAAFFGFGKGTLGYILLGNYFSFEDILCYATGCFLAFIFDK
>NZ_CP022386.1|WP_095909586.1|573830_574346_-|NUDIX-domain-containing-protein
MENIFTYCPHCGSTDVEFPRLVRFLCHQCGFVYYHNIAAAVAVIFRRKDEILFTVRNIDPDKGKLDLPGGFIDPDENAEAAVCREVNEELGLQIVPNQLKYLTTQPNHYLYKNIPYRTMDIFYECPLDVPVSVRAEDEIKSLQWIPLSEIDLGKIGFVSVRTVIEKYYLNQ
>NZ_CP022386.1|WP_095909587.1|574489_576031_+|YifB-family-Mg-chelatase-like-AAA-ATPase
MLVKIYGSAVYGVEAITITIEVNIDKGVGYHLVGLPDNAIKESNYRIEAALHNNQYKIPGKKITINMAPADMRKEGSAYDLSFAIGILAANGQIQCEEIERYIIMGELSLDGSLQPIKGALPIAIQARKEGFKGFILPIQNAKEAAIVNNLEVYGAENIKQVIDFLNGENTLQRVEINTREEFFKHVETPEFDFADVKGQESVKRCMEIAAAGGHNIILIGPPGSGKTMLAKRLPGILPPMTLQEALETTKIHSVVGRVKDNGLICQRPFRSPHHTISDVALVGGGSYPQPGEISLAHNGVLFLDELPEFKRSVLEVMRQPLEDREVTISRTKFSITYPASFMLVASMNPSPSGYFNDPDAPMTSSPAEMQRYLSKISGPLLDRIDIHIEVNPVPFEKLSQREKAESSTSIRERVIQAREIQTQRFAQYEHIHYNAQMGSKQIREYCHVEEASLAMLKKAMERLSLSARAYDRILKVARTIADLEGSESIKEYHIGEAIQYRSLDREGWLGGI
>NZ_CP022386.1|WP_095909588.1|576043_577567_-|lipase
MSPKKIVIFMISVLVSLLWLTFLSNEYMDEENEVAHGIKIGSFQLKYPTFWDIFSHTEAIKNDKAMAIIQGKSPENTSKKDTLATGQFNTKTFVFPEDMTQLRDSIGVFLEGGNPKLVSNVEGQIYYPNPPRDFVKKLHQKLSQPSCRILHYGDSKIEGDRITAYLRNGLQLLYGGTGPGYFPIKMPYGQHSIIEQTSGNWYRYALFNAEQRKNKDLLTNNQYGLYANVCRFAPARGETAGLKTASFTISPSYSYYPTLSQYTDISVHYGNCTVPVLVTVYENNTEIKKDTLIADGAYHAYKLHLSATPKKLRFQFSGTKSPDFYGVTVGSAQGVQVDNIPTRGDSGFHFTRIQDTYDAMSRELKPDIIIFQFGGNLVPYLTKNKVVPSVKRIITNMQWVQKRNPDALFLLIGPSDMLRRSSKTTYDIIPELVAEMKKQAAENGFAFFSMYEAMGGKNSMKIWYDNRMAASDLVHFSDKGTERIAQLLFQNLVEDLLSVQPVEMYKK
>NZ_CP022386.1|WP_095909589.1|577643_580379_-|PD-(D/E)XK-nuclease-family-protein
MFLEQVIEDYLENYADTPTGEVIFITPHRRSALFLRKIFSEKVHKAAISPEFITLDNLLERISGIKKMPDLQGLFELYKVYKEHTESEVDDFEKFVGWGRMLWKDFSDIDQYLIAYKDIFPYMEAIKEAEHWSVGEELTPMQQRHLEFWRTLGTYYNAIHKVMYQQKQGYQGFIARIAYEQIDAYRQANKEKLHLFVGFNALSVAQEKIIQYILEEMQADIYWDIEKHFLNNQHSAGYFIENYLRRWKYYQRERKPKWITEEKTLPEIKIYGTPKQVNQIHLLTTLLEEIPEKEWEQTAIVLSDSDMLLPLLQAIDTNKLPINITMGYPLQQTPVHDLISAYFKLYISGRWYHKEIKALLEQPFLSNLLSENYKRDTITYINEHNFSYVYKKTLDLYVKEGDRELINLLFDDEKDISVSKLIENVIKLLFVIKESLEKSDKENILNLEYIYNFYELFNQIHYLQKKYNYIDNVKSLYYIYNDLLVKQKLSFRGEPLRGLQIMGVLEAQNIYFKNVLITSMNEGIFPKGNSVNSLIPFDVRANLGLPTYKESDYMYSYYFYRILQHTHRAILLYNTDTDGLRGSERSRFVLQLLSDYRIRSQVKFPEVKIIKQNQIEIAKDKNIIEKLVAIATKIDPKHRKGFSPSSLTTYVRNPIDFYQQQILDIRDEAEVEEIVEDRSLGTIIHRILELLYTPYVNSIISKKNINEIRKKVRETTEIVFKEYQQNDEISGKNIFVQQTIEEYVMKFLAIDEKNVSENVVTLLSVEQKIQIDIKFDEFPFPICFNGTIDRVERRGNDIYIVDYKSGIVDREDVKLSDKGWENLILDYKYSKAFQLLMYAYLLFKMGIIQDADNVYVGNYSFRRLKLGFIGFRNQKDKEISLVDSQVREEFEQKLIELLKEIYDPELPFVEK
>NZ_CP022386.1|WP_095909590.1|580455_581346_-|agmatinase
MENTYAGIPAENATYENSKVVLVTVPYDGTSTWGKGADKGPELFLDASENMELYDIETDTEPYLQGIYMAGEVSEKSSPEKMVEAVYQKTKELVKDREKLFTLIGGEHSVSIGSIRAVGEEYHNLTVLQLDAHTDLRPEYHGSKNNHACAVFEANQKHKLVQVGIRSMDAEEKQYLPHKRVFFAHEIAKNDNWIKDVLDKVSGNVYITIDLDAFDPSIAPSTGTPEPGGLQWYPTLKLLKKVFKKCNVVAFDIVELMDSPQAKPTAFLAAKLYYKMLAYYHKYNKNNKEPKKKKGK
>NZ_CP022386.1|WP_095911265.1|581538_582660_+|DNA-polymerase-III-subunit-delta'
MDFETVISNSFAVKYLKETIENDRIAHAQLFSGEEGVGTLAMAIAYATELLSKTGDTNTKLKCEHLTHPDLHFAYPTATTIRVKDHPTSSLFLEEWREFVLRNPYGSLFDWYQFIGIANKQGKIGVDDAKEITSKLSLKSFEGGYKVMIIWMAELMNTECSNKLLKLLEEPPAQTIFILVVENENLLLDTILSRCQITRFTKLGDEVISDALIKQGIDPSQAQKIAIRAQGNYNKALSFLNQNNDNQFEDWFVRWVRMAYSAKGNTEVLPLILAWSEEIAKEGRETQKLFLEYCLEVFRQALLANYGVESLVYMQFNSNFKIQNFAPFVHQNNIQAIQKNIEEAIYHVGRNGNSKLILTDLSIKLIRLIHTKG

Crispr_ID: NZ_CP022386_6

• CRISPR_ID: NZ_CP022386_6
• CRISPR_location: 571999-572096
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP022386_6

Consensus_repeat	Method
TATGACAAAAACAATAACTTACT	CRISPRCasFinder

spacers of NZ_CP022386_6

>6.1|572022|52|NZ_CP022386|CRISPRCasFinder
CTCTAAAATAATTTATAAAGGAAATAAAGAAGTATATAAAGTACTTTATACT

CRISPR arrays and Neighbor proteins around NZ_CP022386_6

CRISPR arrays

The CRISPR arrays of NZ_CP022386_6

>merge|NZ_CP022386|6|571999-572096|CRISPRCasFinder
TATGACAAAAACAATAACTTACTCTCTAAAATAATTTATAAAGGAAATAAAGAAGTATATAAAGTACTTTATACTTATGACAAAAATAATAACTTACT

>NZ_CP022386|6|6|571999-572096|CRISPRCasFinder
TATGACAAAAACAATAACTTACT	CTCTAAAATAATTTATAAAGGAAATAAAGAAGTATATAAAGTACTTTATACT
TATGACAAAAATAATAACTTACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_040360252.1|562217_562655_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909575.1|560829_561474_-|phosphoribosylanthranilate-isomerase	unknown	unknown	gnl|CDD|238237
NZ_CP022386.1|WP_095909576.1|561473_562202_-|indole-3-glycerol-phosphate-synthase	unknown	unknown	gnl|CDD|234710
NZ_CP022386.1|WP_095909591.1|582867_584940_+|methionine--tRNA-ligase	unknown	unknown	gnl|CDD|234655
NZ_CP022386.1|WP_095911265.1|581538_582660_+|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|273213
NZ_CP022386.1|WP_095909590.1|580455_581346_-|agmatinase	unknown	unknown	gnl|CDD|212539
NZ_CP022386.1|WP_095909586.1|573830_574346_-|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240037
NZ_CP022386.1|WP_095909581.1|568306_569479_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909578.1|564309_565590_-|anthranilate-synthase-component-I-family-protein	unknown	unknown	gnl|CDD|223225
NZ_CP022386.1|WP_095909580.1|567283_568294_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909589.1|577643_580379_-|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl|CDD|378929
NZ_CP022386.1|WP_095909582.1|569491_570817_+|ATPase	unknown	unknown	unknown
NZ_CP022386.1|WP_095909577.1|562669_564313_-|anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|237764
NZ_CP022386.1|WP_095909584.1|572252_573449_+|RHS-repeat-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909587.1|574489_576031_+|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl|CDD|223679
NZ_CP022386.1|WP_095909585.1|573474_573834_-|DUF2809-domain-containing-protein	unknown	unknown	gnl|CDD|378530
NZ_CP022386.1|WP_095909579.1|565812_567186_+|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NZ_CP022386.1|WP_095909588.1|576043_577567_-|lipase	unknown	unknown	gnl|CDD|238863
NZ_CP022386.1|WP_095909592.1|584955_585450_+|hydrolase	unknown	unknown	unknown
NZ_CP022386.1|WP_095909574.1|559632_560820_-|tryptophan-synthase-subunit-beta	unknown	unknown	gnl|CDD|235288

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_095909589.1|577643_580379_-|PD-(D/E)XK-nuclease-family-protein	gnl|CDD|378929	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	5.4912e-16
NZ_CP022386.1|WP_095909576.1|561473_562202_-|indole-3-glycerol-phosphate-synthase	gnl|CDD|234710	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC.	1.17045e-95
NZ_CP022386.1|WP_095909591.1|582867_584940_+|methionine--tRNA-ligase	gnl|CDD|234655	PRK00133, metG, methionyl-tRNA synthetase; Reviewed.	0
NZ_CP022386.1|WP_095911265.1|581538_582660_+|DNA-polymerase-III-subunit-delta'	gnl|CDD|273213	TIGR00678, DNA_polymerase_III_subunit_delta', DNA polymerase III, delta' subunit. This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair].	4.56684e-47
NZ_CP022386.1|WP_095909590.1|580455_581346_-|agmatinase	gnl|CDD|212539	cd11593, Agmatinase-like_2, Agmatinase and related proteins. This family includes known and predicted bacterial and archaeal agmatinase (agmatine ureohydrolase; AUH; SpeB; EC=3.5.3.11), a binuclear manganese metalloenzyme that belongs to the ureohydrolase superfamily. It is a key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield urea and putrescine, the precursor for biosynthesis of higher polyamines, spermidine, and spermine. As compared to E. coli where two paths to putrescine exist, via decarboxylation of an amino acid, ornithine or arginine, a single path is found in Bacillus subtilis, where polyamine synthesis starts with agmatine; the speE and speB encode spermidine synthase and agmatinase, respectively. The level of agmatinase synthesis is very low, allowing strict control on the synthesis of putrescine and therefore, of all polyamines, consistent with polyamine levels in the cell. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	1.36089e-107
NZ_CP022386.1|WP_095909578.1|564309_565590_-|anthranilate-synthase-component-I-family-protein	gnl|CDD|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	2.74907e-141
NZ_CP022386.1|WP_095909575.1|560829_561474_-|phosphoribosylanthranilate-isomerase	gnl|CDD|238237	cd00405, PRAI, Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric, monofunctional and thermolabile, but in some thermophile organisms PRAI is dimeric for reasons of stability and in others it is fused to other components of the tryptophan biosynthesis pathway to form multifunctional enzymes.	4.50194e-69
NZ_CP022386.1|WP_095909577.1|562669_564313_-|anthranilate-phosphoribosyltransferase	gnl|CDD|237764	PRK14607, PRK14607, bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase.	1.72563e-175
NZ_CP022386.1|WP_095909574.1|559632_560820_-|tryptophan-synthase-subunit-beta	gnl|CDD|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0
NZ_CP022386.1|WP_095909587.1|574489_576031_+|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl|CDD|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP022386.1|WP_095909585.1|573474_573834_-|DUF2809-domain-containing-protein	gnl|CDD|378530	pfam10990, DUF2809, Protein of unknown function (DUF2809). Some members in this family of proteins are annotated as yjgA however currently no function for the protein is known.	1.91384e-21
NZ_CP022386.1|WP_095909579.1|565812_567186_+|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP022386.1|WP_095909588.1|576043_577567_-|lipase	gnl|CDD|238863	cd01825, SGNH_hydrolase_peri1, SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.11482e-29
NZ_CP022386.1|WP_095909586.1|573830_574346_-|NUDIX-domain-containing-protein	gnl|CDD|240037	cd04681, Nudix_Hydrolase_22, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.39488e-43

Protein sequences

>NZ_CP022386.1|WP_095909582.1|569491_570817_+|ATPase
MKHLLIPFLFITTVIVAQNTANKVEKYKIDSDLAYPFEKPLLGKVKKVHTAHYSTVVTVLKDTIKREHFVENYTYGFDERGNEIEFIKYDKEGNIWNKEIKKYNEKDRLLYSKETKILGEDETYIEENSYSYNDKGFLIEEKSYEEDPDTGISHRRELYKYNNDQKLIENSYYSNDSLKRQVLYWYDNKGNLLRKLFYLDNKPYTDTKFEYNHIGNLIKKTENYIKTDYKHVKQYEYDAKNRLILFTKEDDDTKEIILKIIYKDDLLIEIYDNRDDEEVHIFYSYKNKKLINKVISKSFFNGCYYDYIKEKILYDEKGRIKKSFDYKQNKIKKTYTYYYDNKDRVIKTELLYTGDKKEYWIDNYDTIGNLIETIYKNDDYRDKDSYTYDNNNNLLSKITYKGNKAIEKTFYTYDKYQNIIKIEKYNNGKNYIYERTFTYYE
>NZ_CP022386.1|WP_095909581.1|568306_569479_+|hypothetical-protein
MKNYLLPFLFFCSTLVAQNTTYKDTTSYKTNEKYDQFFPKPLRGKIKTMHTVGCRIEYQEDTPVAVYHLFHKNKIDPYTYTYHFDKRGNDIAFYTYDALGNLMDWEIKTFNKADSLTYRKISYVIDSIRHSAERFNLYNDKNLLVERKDIDRYGSKVSLYFYNEEDNIIKEEDYYKGKLFYTALYTYDAKGKLLEKKEKEKNPKKHSTTIYEYDTLGNLIRITEKEKGEKSYILTNRIYENNTLIKEYDDHSYVLYTYKEGKLIETESYYTGIGIDYIIDRKVITKYNEKGQIIKKLEYQGNILEQETNYFYDENGKEIKGILYKGGKEKSRWENKYSPKGYLIEKAWKREKGNPKTLYYYDAIGNCIKIEEYYKGKLTNIYERIFTYYE
>NZ_CP022386.1|WP_095909580.1|567283_568294_+|hypothetical-protein
MKNYLLPFLFLFSIVIWGKNDPLPRKNRKTHKTIGDFFGKVKSLSSISCKVINDYKGDIIRTTRENYDHEYYYLFDEKGNITQTNKYDNSNKLIEEKKFLYSYNENDLLIKELYYKNNDLIGSYTYKYDKNANKIEETYEDTQKNYKYIRKYKYDDKNRLIFVKEKNTDREDTLNIFKRTYKDDLLMEEYYGEKNYSYTHTYFYENKKLKTKKEESSSFEGCYFTNTETIYTHNDKELPISCDVYISHKLQNNITYEYDEKGKEIKRVYTFPDDSQYNSYVTYQYDKKGNLIEENNSRLSEKIIYFYDEHNNWIKQEVYYNDKLSHIYERAFTYYE
>NZ_CP022386.1|WP_095909579.1|565812_567186_+|DNA-repair-protein-RadA
MAKTKTAFFCQNCGAQYSKWQGQCYACKEWNTIVEEVIQKEEKHQWKKDDESDTPRSKKTNKYIPLHEITTEKEMRLDSGDQELNNVLGGGIVPGSVVLIGGEPGIGKSTLLLQIAMRMPYKTLYVSGEESQKQIKMRGERITNARNNCYILTETKTQNIFQQIKELDPEILIIDSIQTLHSDYIEASAGSISQIRECTAELIKYAKLTGVPVIIVGHITKDGTIAGPKILEHMVDTVLQFEGDRNHVFRILRALKNRFGSTSELGIYEMLSTGLREVSNPSEVLLSKTDENSSGTAIVATIEGMRPLMIEIQALVSSAVYGTPQRSTTGFNAKRLNMLLAVLEKRAGFRLGSKDVFLNITGGISVDDPSTDLGVAMAILSSNEDVAIPKTFCFAAEVGLGGEIRPVQRVEQRISEAEKLGFDTIFISKYCKLTAGKRNINVITYAKVEEVIAHLFG
>NZ_CP022386.1|WP_095909578.1|564309_565590_-|anthranilate-synthase-component-I-family-protein
MFLTAPPLFYYTFIKERYKNSYLAEDVNQVIIGIDCDYLDAYKYSYTSLEQYHQRQKSIAPFAGLFGVFSYETIHFFEQIPEKSQKQYDFPAFVFANAKAYLHYSKVSKVYSFYGDEQQYFHFLEEATVQENPTGPEVFYQLHTDLAQERAHFYQMVEKAKEYIRSGDIFQVVLSEQLSLESNLDSLDFYRYLSQANPSPYMFHFPTPYGEVVGSSPEILVDITGSQIHIAPIAGSRPRGKDANEDLRLEQELLADPKECAEHRMLVDLARNDIGKFAQKGSVVVKDMMQILRYEHIMHIESHVYGDKRTEVSPFEVISIVFPAGTLSGAPKIRAMEIINELESFRRNVYGGGIGFLHFNGNVQLAIVIRSAFFEKANAENEQVSKVFIQAGAGIVYDSVSEKEYDEICHKRASVLNVFTKNCKEK
>NZ_CP022386.1|WP_095909577.1|562669_564313_-|anthranilate-phosphoribosyltransferase
MILLIDNYDSFVFNVAQYLQELTEEEVKTVRNDAITWEEITALNPSRIVLSPGPKHPKDSGICLEILQKNTTIPVLGICLGHQAFGMVNGAEIKRMEMPLHGKTSALRVTDDNTLLFRGLPKQFQVMRYHSLYVGKEQLPENIRITALSDDDIIMALEHKEKPIYSIQFHPESFFTEYGKHIIKNFITYTQKLQPSVADDHAQEKARANEVFKTALKKLQENIPLTDGDFKEICEVIHTKQYDIVQLGALLVLISEKSLYPESLTAFVRNILAYSTTFADESPMIDLCGTGGDGLKTINISTTVAFIVAAMGVKVAKHGNRSVTSQSGSSDVLGQLGIPLENNLLTQLEHLQKEHLAFFHAPFFHPLVGEVKEVRQRLGIRTVFNVLGPLLHPNAKLKYQLVGLYHEPVQRLYAETLQLLGRKHALVVRGNDGLDEITLCDETKIVEVKDGKILEYTIAPEMFGFKRAFHADIQGGTPEENAEILLRTLKGEEQSPKSDIVILNAMFALYTADFVKHPADAKPLIQEAIRSGKVYEHYLKMINANKE
>NZ_CP022386.1|WP_040360252.1|562217_562655_-|hypothetical-protein
MRQKLLKYVLFIMAIFVTDAVFLFLSMKDYKDSMSSSCLECSFWKDIFVFLLIGMGVLAILLTILFRIVKKRGYLYGLILISLLSIFYSIDYMLFVDRVAAWSTYSLKETWITIFWDSYRYFPMLMLIYVLLTNRLIKEIESINN
>NZ_CP022386.1|WP_095909576.1|561473_562202_-|indole-3-glycerol-phosphate-synthase
MDILSQIKQQRDLQLQRELASVARPSFHKALSQEGIRIIGEIKRASPSKGQIALENFDLLKQATHYVEHGVAAFSILTEEAYFKGDNTFIPQVVEAFPKVPILRKDFIYTPFQVAQAKFLGASAILLIVRMLSDEQLQALHALAYDLQMDVLVEVHDEAELQRALRIPQLKILGINNRNLNTFEVSLQTTERLLSLISEEQRAPLLVVSESGYLSKEDLHYAETLGVDALLIGEALMKGLLF
>NZ_CP022386.1|WP_095909575.1|560829_561474_-|phosphoribosylanthranilate-isomerase
MEKTALKICGIRSLEEIQDLKNLPIDYFGCIFAPRSPRCVSLALAKEITEIAHSEGKQTVGVFVNASLEQIADTVNLTGIDVVQLHGEESPDICKMLTTKGITVWKAFSIKDKLLPMEDYLPYMDLPLLDTKGVSEGGNGLVFNWQLLERLTPYSFILAGGISAENVQKALSYQPAIIDVNSKVEQDNRKSRQLIEKLIKEMEKYRRGIEKYNK
>NZ_CP022386.1|WP_095909574.1|559632_560820_-|tryptophan-synthase-subunit-beta
MTNKAYFGNFGGQYVPETAMFALIELEKEYEKAKNDPCFQAELEDLLKNYVGRPTPLYYAKNLSAHYGHDIFLKREDLNHTGAHKINNALGQVLLAKRMGKKKVIAETGAGQHGVATATAAALLGLECEVYMGAVDMERQQLNVFRMELLGAKVVAIEDGLKTLKEATTAAIQSWVAEIETVFYVIGSVVGPHPYPTIVRDFQSIIGREARKQLATQDRHADHVIACVGGGSNAIGIFAGFLDDPATQLYGVEAGGEGIDTDRHAATLTLGREGIIHGMKTYVLQDKYGQISPVHSISAGLDYPGIGPEHAHLFQTKRAHYAPITDTEAMEALLLTTRKEGIIPAIESAHALAYLSKLCPTLPKDKKQTIVVNVSGRGDKDMHTVFSILKGEKYE
>NZ_CP022386.1|WP_095909584.1|572252_573449_+|RHS-repeat-protein
MKYFLFTLLFYFSSCFYVSLLAQEDDPNRYREEHLRNLGITPQGKVKSVEKFIYHYENRNGKEVKIFPKNAKVERMPVHSRYTFDKKGNIIEFYNYHTDGKLFQKIFYQYNGDNLLTKADEYKYIEENNPQHTEEEIFYEGKVMISKKYKIDGNLFEIRMLFDKNKRKKAISEYRNNTLINKNKYSYNSKGNITYEKNKSMSLLGDEAYDTWYTYTKDGTLLAEKKECYSIFCFYTTYQYLANDEVYEETTYTTPLSDEKDVSNKKTKYYIYDSKGAIVEIQTYKGEDFRSYHCMENDKEVETYSYFLEGEVIKTLFSYNKDNQLIKEENFNLLTGDFTSGTYYMYDEKGNLLQIDDGQIPSPNRTIYHYDKFNNCTEEIYYKNNKRVAIVERIFNYY
>NZ_CP022386.1|WP_095909585.1|573474_573834_-|DUF2809-domain-containing-protein
MKFNSKYFFAALIIFLVEVAIATVFKSVPFVRAYLGDILVVILIYCFIRAFFHIKNTKKLLIGIFCFAVFVEILQYFKLAAFFGFGKGTLGYILLGNYFSFEDILCYATGCFLAFIFDK
>NZ_CP022386.1|WP_095909586.1|573830_574346_-|NUDIX-domain-containing-protein
MENIFTYCPHCGSTDVEFPRLVRFLCHQCGFVYYHNIAAAVAVIFRRKDEILFTVRNIDPDKGKLDLPGGFIDPDENAEAAVCREVNEELGLQIVPNQLKYLTTQPNHYLYKNIPYRTMDIFYECPLDVPVSVRAEDEIKSLQWIPLSEIDLGKIGFVSVRTVIEKYYLNQ
>NZ_CP022386.1|WP_095909587.1|574489_576031_+|YifB-family-Mg-chelatase-like-AAA-ATPase
MLVKIYGSAVYGVEAITITIEVNIDKGVGYHLVGLPDNAIKESNYRIEAALHNNQYKIPGKKITINMAPADMRKEGSAYDLSFAIGILAANGQIQCEEIERYIIMGELSLDGSLQPIKGALPIAIQARKEGFKGFILPIQNAKEAAIVNNLEVYGAENIKQVIDFLNGENTLQRVEINTREEFFKHVETPEFDFADVKGQESVKRCMEIAAAGGHNIILIGPPGSGKTMLAKRLPGILPPMTLQEALETTKIHSVVGRVKDNGLICQRPFRSPHHTISDVALVGGGSYPQPGEISLAHNGVLFLDELPEFKRSVLEVMRQPLEDREVTISRTKFSITYPASFMLVASMNPSPSGYFNDPDAPMTSSPAEMQRYLSKISGPLLDRIDIHIEVNPVPFEKLSQREKAESSTSIRERVIQAREIQTQRFAQYEHIHYNAQMGSKQIREYCHVEEASLAMLKKAMERLSLSARAYDRILKVARTIADLEGSESIKEYHIGEAIQYRSLDREGWLGGI
>NZ_CP022386.1|WP_095909588.1|576043_577567_-|lipase
MSPKKIVIFMISVLVSLLWLTFLSNEYMDEENEVAHGIKIGSFQLKYPTFWDIFSHTEAIKNDKAMAIIQGKSPENTSKKDTLATGQFNTKTFVFPEDMTQLRDSIGVFLEGGNPKLVSNVEGQIYYPNPPRDFVKKLHQKLSQPSCRILHYGDSKIEGDRITAYLRNGLQLLYGGTGPGYFPIKMPYGQHSIIEQTSGNWYRYALFNAEQRKNKDLLTNNQYGLYANVCRFAPARGETAGLKTASFTISPSYSYYPTLSQYTDISVHYGNCTVPVLVTVYENNTEIKKDTLIADGAYHAYKLHLSATPKKLRFQFSGTKSPDFYGVTVGSAQGVQVDNIPTRGDSGFHFTRIQDTYDAMSRELKPDIIIFQFGGNLVPYLTKNKVVPSVKRIITNMQWVQKRNPDALFLLIGPSDMLRRSSKTTYDIIPELVAEMKKQAAENGFAFFSMYEAMGGKNSMKIWYDNRMAASDLVHFSDKGTERIAQLLFQNLVEDLLSVQPVEMYKK
>NZ_CP022386.1|WP_095909589.1|577643_580379_-|PD-(D/E)XK-nuclease-family-protein
MFLEQVIEDYLENYADTPTGEVIFITPHRRSALFLRKIFSEKVHKAAISPEFITLDNLLERISGIKKMPDLQGLFELYKVYKEHTESEVDDFEKFVGWGRMLWKDFSDIDQYLIAYKDIFPYMEAIKEAEHWSVGEELTPMQQRHLEFWRTLGTYYNAIHKVMYQQKQGYQGFIARIAYEQIDAYRQANKEKLHLFVGFNALSVAQEKIIQYILEEMQADIYWDIEKHFLNNQHSAGYFIENYLRRWKYYQRERKPKWITEEKTLPEIKIYGTPKQVNQIHLLTTLLEEIPEKEWEQTAIVLSDSDMLLPLLQAIDTNKLPINITMGYPLQQTPVHDLISAYFKLYISGRWYHKEIKALLEQPFLSNLLSENYKRDTITYINEHNFSYVYKKTLDLYVKEGDRELINLLFDDEKDISVSKLIENVIKLLFVIKESLEKSDKENILNLEYIYNFYELFNQIHYLQKKYNYIDNVKSLYYIYNDLLVKQKLSFRGEPLRGLQIMGVLEAQNIYFKNVLITSMNEGIFPKGNSVNSLIPFDVRANLGLPTYKESDYMYSYYFYRILQHTHRAILLYNTDTDGLRGSERSRFVLQLLSDYRIRSQVKFPEVKIIKQNQIEIAKDKNIIEKLVAIATKIDPKHRKGFSPSSLTTYVRNPIDFYQQQILDIRDEAEVEEIVEDRSLGTIIHRILELLYTPYVNSIISKKNINEIRKKVRETTEIVFKEYQQNDEISGKNIFVQQTIEEYVMKFLAIDEKNVSENVVTLLSVEQKIQIDIKFDEFPFPICFNGTIDRVERRGNDIYIVDYKSGIVDREDVKLSDKGWENLILDYKYSKAFQLLMYAYLLFKMGIIQDADNVYVGNYSFRRLKLGFIGFRNQKDKEISLVDSQVREEFEQKLIELLKEIYDPELPFVEK
>NZ_CP022386.1|WP_095909590.1|580455_581346_-|agmatinase
MENTYAGIPAENATYENSKVVLVTVPYDGTSTWGKGADKGPELFLDASENMELYDIETDTEPYLQGIYMAGEVSEKSSPEKMVEAVYQKTKELVKDREKLFTLIGGEHSVSIGSIRAVGEEYHNLTVLQLDAHTDLRPEYHGSKNNHACAVFEANQKHKLVQVGIRSMDAEEKQYLPHKRVFFAHEIAKNDNWIKDVLDKVSGNVYITIDLDAFDPSIAPSTGTPEPGGLQWYPTLKLLKKVFKKCNVVAFDIVELMDSPQAKPTAFLAAKLYYKMLAYYHKYNKNNKEPKKKKGK
>NZ_CP022386.1|WP_095911265.1|581538_582660_+|DNA-polymerase-III-subunit-delta'
MDFETVISNSFAVKYLKETIENDRIAHAQLFSGEEGVGTLAMAIAYATELLSKTGDTNTKLKCEHLTHPDLHFAYPTATTIRVKDHPTSSLFLEEWREFVLRNPYGSLFDWYQFIGIANKQGKIGVDDAKEITSKLSLKSFEGGYKVMIIWMAELMNTECSNKLLKLLEEPPAQTIFILVVENENLLLDTILSRCQITRFTKLGDEVISDALIKQGIDPSQAQKIAIRAQGNYNKALSFLNQNNDNQFEDWFVRWVRMAYSAKGNTEVLPLILAWSEEIAKEGRETQKLFLEYCLEVFRQALLANYGVESLVYMQFNSNFKIQNFAPFVHQNNIQAIQKNIEEAIYHVGRNGNSKLILTDLSIKLIRLIHTKG
>NZ_CP022386.1|WP_095909591.1|582867_584940_+|methionine--tRNA-ligase
MSERYTITAALPYTNGPIHIGHLAGVYVPADIFARYQRLKNNDVAFICGSDEHGVAISIKAKKEGTTPQEIIDKYNKIIKDSLFDFGISFDNYSRTSLPIHYQTASEFFRTLYDKGDFIEETSEQLYDEQAGQFLADRFVIGTCPKCGNEEAYGDQCERCGTSLNATDLINPKSTLTGSKPVLRQTKHWFLPLQDYTEFLEKWIIEGHKNDWKPNVYGQVKSWIDDGLRPRAVTRDLDWGIPVPVEGAEGKVLYVWFDAPIGYISSTKEWAAREGKDWEPYWKDKETKLIHFIGKDNIVFHCIIFPAMLKAEGSYILPENVPANEFLNLEGNKLSTSKNWAVWLNEYLEEFPSQQDTLRYVITANAPETKDNDFTWKDFQARNNNELVAIYGNFINRVMVLTDKYYKGVVPSVGELTQVDREVFAQIKELIQKIEQSLERYRFREAQQELMNIARLGNKYLADEEPWKLIKEDPKRVETIMYIALHIATALAVTSEPFLPFTSEKLKRMLNFSTMEKAPTWQDIPLSDRLIPQGHTIGESVLLFEKIEDEAIEKQIAKLEKSKQANKQAITNDHTTVVPQKELISYEDFAKMDIRIGTILEAEKMPKADKLLILKVDTGIDQRTIVSGIAQSFDPKEIIGKKVTVLANLAPRKLRGVESHGMILMVENSAGKYVFLNPDAEGIANGTEVK
>NZ_CP022386.1|WP_095909592.1|584955_585450_+|hydrolase
MKQLTLPLFLLGSTLVLSCKNNTEEKKTPEKENTTISVERLQDSIQKLSDDLAEERYFDISFNEDARYFFHENGIDDPKEFVLQQLMATNITKDENHPLISYRPRRNAKFQINKIKLLNHRWVICDFSDGLDWGELLLKMTLNDNKTLSFEVLDQTLYVSEQKP

Crispr_ID: NZ_CP022386_7

• CRISPR_ID: NZ_CP022386_7
• CRISPR_location: 1153704-1153793
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP022386_7

Consensus_repeat	Method
CTATCAAATGACCATCAAATAAAAA	CRISPRCasFinder

spacers of NZ_CP022386_7

>7.1|1153729|40|NZ_CP022386|CRISPRCasFinder
CTCATTGAATATCAATGATTTAATTTTCAAAAGGACTTTC

CRISPR arrays and Neighbor proteins around NZ_CP022386_7

CRISPR arrays

The CRISPR arrays of NZ_CP022386_7

>merge|NZ_CP022386|7|1153704-1153793|CRISPRCasFinder
CTATCAAATGACCATCAAATAAAAACTCATTGAATATCAATGATTTAATTTTCAAAAGGACTTTCCTATCAAATGACCATCAAATAAAAA

>NZ_CP022386|7|7|1153704-1153793|CRISPRCasFinder
CTATCAAATGACCATCAAATAAAAA	CTCATTGAATATCAATGATTTAATTTTCAAAAGGACTTTC
CTATCAAATGACCATCAAATAAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_002669315.1|1158016_1159003_+|porphobilinogen-synthase	unknown	unknown	gnl|CDD|236450
NZ_CP022386.1|WP_095909991.1|1155681_1156143_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909983.1|1145369_1146641_-|serine--tRNA-ligase	unknown	unknown	gnl|CDD|235461
NZ_CP022386.1|WP_095909995.1|1160088_1161054_-|hydrogen-peroxide-inducible-genes-activator	unknown	unknown	gnl|CDD|176103
NZ_CP022386.1|WP_095909989.1|1154012_1154729_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909982.1|1144460_1145207_+|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl|CDD|184516
NZ_CP022386.1|WP_157909418.1|1154853_1155531_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909992.1|1156608_1156989_-|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl|CDD|376605
NZ_CP022386.1|WP_095909993.1|1157051_1157738_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909981.1|1143587_1144370_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|378270
NZ_CP022386.1|WP_095909986.1|1149440_1150118_-|NAD-dependent-deacylase	unknown	unknown	gnl|CDD|238703
NZ_CP022386.1|WP_095909988.1|1152382_1153375_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_002669148.1|1162127_1162991_+|geranylgeranylglycerol-phosphate-geranylgeranyltransferase	unknown	unknown	gnl|CDD|260124
NZ_CP022386.1|WP_002669183.1|1147753_1148422_+|uroporphyrinogen-III-synthase	unknown	unknown	gnl|CDD|119440
NZ_CP022386.1|WP_095909985.1|1148425_1149454_+|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|238368
NZ_CP022386.1|WP_002669335.1|1142884_1143595_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP022386.1|WP_095909987.1|1150122_1152414_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095909996.1|1161239_1162118_+|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|225088
NZ_CP022386.1|WP_095909984.1|1146934_1147573_-|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NZ_CP022386.1|WP_095909994.1|1159107_1159998_+|exopolyphosphatase	unknown	unknown	gnl|CDD|274735

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_002669315.1|1158016_1159003_+|porphobilinogen-synthase	gnl|CDD|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NZ_CP022386.1|WP_095909992.1|1156608_1156989_-|large-conductance-mechanosensitive-channel-protein-MscL	gnl|CDD|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	3.60796e-53
NZ_CP022386.1|WP_095909983.1|1145369_1146641_-|serine--tRNA-ligase	gnl|CDD|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NZ_CP022386.1|WP_095909995.1|1160088_1161054_-|hydrogen-peroxide-inducible-genes-activator	gnl|CDD|176103	cd08411, PBP2_OxyR, The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily. OxyR senses hydrogen peroxide and is activated through the formation of an intramolecular disulfide bond. The OxyR activation induces the transcription of genes necessary for the bacterial defense against oxidative stress. The OxyR of LysR-type transcriptional regulator family is composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The C-terminal domain also contains the redox-active cysteines that mediate the redox-dependent conformational switch. Thus, the interaction between the OxyR-tetramer and DNA is notably different between the oxidized and reduced forms. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.50265e-64
NZ_CP022386.1|WP_095909982.1|1144460_1145207_+|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl|CDD|184516	PRK14115, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	5.32032e-170
NZ_CP022386.1|WP_095909994.1|1159107_1159998_+|exopolyphosphatase	gnl|CDD|274735	TIGR03706, exo_poly_only, exopolyphosphatase. It appears that a single enzyme may act as both exopolyphosphatase (Ppx) and guanosine pentaphosphate phosphohydrolase (GppA) in a number of species. Members of the seed alignment use to define this exception-level model are encoded adjacent to a polyphosphate kinase 1 gene, and the trusted cutoff is set high enough (425) that no genome has a second hit. Therefore all members may be presumed to at least share exopolyphospatase activity, and may lack GppA activity. GppA acts in the stringent response. [Central intermediary metabolism, Phosphorus compounds].	1.00339e-66
NZ_CP022386.1|WP_095909981.1|1143587_1144370_+|ABC-transporter-permease	gnl|CDD|378270	pfam09843, DUF2070, Predicted membrane protein (DUF2070). This is a family of Archaeal 7-TM proteins. There are 6 closely assembled TM-regions at the N-terminus followed by a long intracellular, from residues 220-590, highly conserved region, of unknown function, terminating with one more TM-region. The short 25 residue section between TMs 5 and 6 might lie on the outer surface of the membrane and be acting as a receptor (from TMHMM).	0.00084002
NZ_CP022386.1|WP_095909986.1|1149440_1150118_-|NAD-dependent-deacylase	gnl|CDD|238703	cd01412, SIRT5_Af1_CobB, SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span. CobB is a bacterial sirtuin that deacetylates acetyl-CoA synthetase at an active site lysine to stimulate its enzymatic activity. .	1.68428e-102
NZ_CP022386.1|WP_002669148.1|1162127_1162991_+|geranylgeranylglycerol-phosphate-geranylgeranyltransferase	gnl|CDD|260124	cd13961, PT_UbiA_DGGGPS, Geranylgeranylglycerol-phosphate geranylgeranyltransferase. Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.	1.74518e-65
NZ_CP022386.1|WP_002669183.1|1147753_1148422_+|uroporphyrinogen-III-synthase	gnl|CDD|119440	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in the human uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria, a recessive inborn error of metabolism also known as Gunther disease.	1.78215e-34
NZ_CP022386.1|WP_095909985.1|1148425_1149454_+|uroporphyrinogen-decarboxylase	gnl|CDD|238368	cd00717, URO-D, Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction is located at the branching point of the tetrapyrrole biosynthetic pathway, leading to the biosynthesis of heme, chlorophyll or bacteriochlorophyll. URO-D deficiency is responsible for the human genetic diseases familial porphyria cutanea tarda (fPCT) and hepatoerythropoietic porphyria (HEP).	0
NZ_CP022386.1|WP_002669335.1|1142884_1143595_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.34824e-69
NZ_CP022386.1|WP_095909996.1|1161239_1162118_+|FtsX-like-permease-family-protein	gnl|CDD|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	3.84709e-38
NZ_CP022386.1|WP_095909984.1|1146934_1147573_-|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.08784e-36

Protein sequences

>NZ_CP022386.1|WP_095909988.1|1152382_1153375_-|hypothetical-protein
MKKLLLFFLVFVSLACQRTTPVASLAVYYWRTSLSLTPEQEGFLTEQRITKLYVRYCDVGLRGGEAVPIAPIEMDSVALVGKQVVPVIYLKNEVFLDKQTDPKALAAKVGKYIEQINNSYHLTVGEVQFDCDWSLSSKERYFAFLEHFRGLYPYHLSATIRLHQVKYQDTTGVPPVERGVLMYYNMGKITATGSNSIYDREVAKRYLPSLRGYPLPLDLALPLFSWGVHSIAGDVNALIGGLTTAQMDTIKGVERMGETSSYLVTHQTNYLGRLWQKGDVVKVEEITPENLREMKADLIKYMKQPPKEIILYDLNKNITTYEKKLFEDLR
>NZ_CP022386.1|WP_095909987.1|1150122_1152414_-|hypothetical-protein
MKKNFLKTCVKLSVLAGIGYGAYLYACAGEGLGDYYNSVFSPEIAVGNTSYKALFLSEDSFFYGGYIDIDEKKSDQLTADAKEWRTYLGQAKQPNAESWLSLFFNPKTKLQDAQKALRRIEQKEYPKKTQNFVDFLRIAVGNEGATNMPYDPWNYENRKVEKVQQLQIQKADNLYASAQKDKDAFFANRMWFQALRLRFYSYDRSAVIAYFEQTHRDQPKNALYYRALHYVAGAYIAQKNYRKANALLATLFHEVPALRQTATYEYHPLTDNEVSAIAQGLQPSQAAALWAMQGYYRNEKEAIEHILALEPRSPYVDFLLTRYINRIEIKTNTYDDKWVIMASYKGYRSYTHRVVTKDFDTQWVLQTAQKETLANPYLWHIAAGYLSMFRNDFQGAASFLKKAKTEAKNTAMQDQVRLLETLNEVSSLEQISKEAEDKLLKDIQWLWTHKKNEDMRYGYAFSFVRAYLSRLYKEANNTLMWELTSPQAGFYKNGQQSLAMEQLLLKGNKTPWEKFWAEYYTYTLGDIYESRAIYAFYEDNISKAIAELKKVPFQEENVYNEVTRRMEKKKIKLSDYILPANPFNGFIKDCNDCQHAMPQKVKYSKLSFLEKVKEMQGKITKGEDVYNNALLIGNAFYNASYFGSIRAFYHNRIIGEYGLGINPENQEVLLGMGNAKKYYLLAQKHATTDEQRAKMAYLLAKIERNEFYIEAYFSKPDNYGGAWADDVLVKDWKGFQELRNKYRHTQYYKEVIRECGYFRKTIK
>NZ_CP022386.1|WP_095909986.1|1149440_1150118_-|NAD-dependent-deacylase
MQKLVVLTGAGISAESGISTFRDSGGLWEGYDVNQVATPEGFAADPALVLDFYNQRRRQLSQVEPNEAHRLLAHLEKRYEVVIITQNVDDLHERAGSHNIIHLHGELLKSRGVDNPEVTYPCTGDIHVGDKSPTGAQLRPHIVWFGEEVPMLEKAIAQVYSADILMIIGTSLQVYPAASLIDYVKEGTPIFYIDPNPSLHSKGDLTVIAQKASTGVAKAIELMTP
>NZ_CP022386.1|WP_095909985.1|1148425_1149454_+|uroporphyrinogen-decarboxylase
MIKNDLFLRILQGEKTERPAVWMMRQAGRYLPEFRALRAKYDFFTRCRTPELVAEITTQPVDIVGVDAAILFSDILVVPQAMGIHIEMKEQVGPYLPHPIRTKADIERVQIPEVSEALGYVMEGIRLTKERLAGEVPLIGFAGAPWTIFCYAVEGKGSKNFDTAKSFAFSYPEWTAEFLQKITDTTIAYLREKVKAGVDALQLFDSWGGVLSAEDYQKYSWPYTRQIVEALSEEVPVIVFAKGCWYALEEMSQSKAAALGVDWTCSPEMARKLTGGKKVLQGNLDPAWLLAPITQIKEKTQQMIRAFGKEHYIANLGHGILPEVPVEHARAFVEAVKNFKES
>NZ_CP022386.1|WP_002669183.1|1147753_1148422_+|uroporphyrinogen-III-synthase
MIRLLSTKLLLPQEVEAFAALGFQVESLPLIRVQLSETIEAFPQADFAIFTSGNALEALQKHPAAKALAPHRAFCVGAKTRERLESAGWEVIASFGYAQQLANYLVEQYASYSFVFFCGESRMETLPKVLAKRGIPCHECLTYTTELTPKKLSKHYDGLLFFSPSAVRSFLAANSFAEEKIFCIGSTTQSALPEGVSSYIAQSPTLEGMMERCREIFNNRQT
>NZ_CP022386.1|WP_095909984.1|1146934_1147573_-|C40-family-peptidase
MKKILPILLFFAGTAYHQEVQAQNRPSKPLVDNPTYLEGKNDMLIAATDFGNISRYENAVIDESMPISRRGELLVKPDLEAMGAEDRVVALIDAAYSYIGTPYKWSGTTREGMDCSGFVSTAFSSINVPLSRSSTEMSTQGVDIPLSQAQVGDLLFFKTTRKRNRISHVGIVVGTGDEVKFIHASTSQGITVSSLSEDYWQKAYAKTSRVLK
>NZ_CP022386.1|WP_095909983.1|1145369_1146641_-|serine--tRNA-ligase
MLQISYIRENKEKVLTGLKKRNFGELELVEQAIALDEKRRALQTELDEALSKSNKLSKEIGALMKEGKKEEAEAAKEQTAQYKELTKRLNAELDQTATSLTQVLYRIPNIPNEIVPEGKSAEDNLNVFQAGEIPALYEGALPHWELAKKYDIIDFELGVKLTGAGFPVYKGKGAKLQRALISYFLDKNTAAGYQEFQVPHMVNEDSGYGTGQLPDKEGQMYHVQLDNLYLIPTAEVPVTNIFRDVILSEADFPICCTAYTPCFRREAGSYGAHVRGLNRLHQFDKVEIVRIEHPDRSYQALTQMVEHVKGILNELKLPYRILRLCGGDLGFTSAITYDFEVYSTAQEKWLEISSVSNFETFQANRLKLRFRNSEGKTQLVHTLNGSSLALPRVLAGILENYQTPEGILIPEVLRKYTGFDIIN
>NZ_CP022386.1|WP_095909982.1|1144460_1145207_+|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MYKVVLLRHGQSEWNKLNLFTGWQDVDLTEQGVQEAREAGRVLKEEGFRFDVAYTSVLKRAIKTLNNALEVMGELWVPTYKSWRLNEKSYGALQGLNKAETAAKYGEDQVLLWRRSYDVQPPLLEKSDERHPSHDRRYDTLTDAEKTAGESLKDCYDRMLPLWFSDIAPAIKQGKSVIIAAHGNSLRSLVQYLDSLSEEEILKLNIPTGVPLVYELDADLKPIKHYYLGDQEAIAAAINSVANQGKKQ
>NZ_CP022386.1|WP_095909981.1|1143587_1144370_+|ABC-transporter-permease
MLKIIRYTFFDLIRSSWTYFYFGFYLILSSILLFLNHDISKSVITLMNVIIVLIPLISTIFGVMYYYNAREFIELLLAQPIPRKHIFLGQYLGISLSLSLSLVIGLGVPFLLYGLFLSSEIFNFLMLIVTGVFLSFIFVGISYLIGLYYENKIKGFSLAIFIWLFMAVIFDGIFLICFMVFRQYPLDSFSLAMILANPIDLSRILILLKLDISALMGYTSAFFKSFFGSTTGIAASLGSLSLWVIAIIFLILRKIKRKDF
>NZ_CP022386.1|WP_002669335.1|1142884_1143595_+|ABC-transporter-ATP-binding-protein
MIEFKDIHKKYGKLEVLKGVNFTIKDGGIIAILGPNGSGKTTSMKSFLGMVVPTKGDILFNGKSIKGQWAYREQISYLPQIANFPSNLKVKELISMIKNIKKVPCNDQELIELFGLQKHLNKSLGNLSGGTKQKVNLVLTFMVDVPVLVLDEPTSGLDPIAVLALKKLILREKEKGKTILITSHILSFLEELSDEILFILEGNIYFRGTPQELLATTQKDNFQEAIAELLKNEKYA
>NZ_CP022386.1|WP_095909989.1|1154012_1154729_-|hypothetical-protein
MKKIFYILVSIAFIVLVIIFISKKNSIKLDNNTHKNLILATKKVKSNDKYDTIITPKDYDCKEDFHRYSNYQKRFNLYISTFYEIDEAIKTPNNDSIAILRPYYSTLGATNCLPNREYEWLLLAKKGNDEAKYKIYKQALYSVGYHSVHSLSTYENGFIINVDMSGNNYFGSKIYVNSQYCIDSIHVESWGHHQYEKTYKYKNFSLDNFTYHHIDNLREESDKMDNKKRKKEGLPPIL
>NZ_CP022386.1|WP_157909418.1|1154853_1155531_-|hypothetical-protein
MINLLIKFVFYFFMMSAFFKSIYPIKFDKELNKGVKIENIDTIFAPKDIFKYNCNYNVKQYEKRYNYHISKFYIIGDENVLSNNDSLATLTPFYIEGLGDCYPEKIHKKLLIIQRKNIKNQNKTKIYNDVLYPDIHQEISKYKEGFVIEVYMSGVSGFRSDTYVNSQYCIDSIHIESWGHHQYEKTYKYKNFSLDNFTYHHIDNLRKKNDKMDNIRRKKEGLPIL
>NZ_CP022386.1|WP_095909991.1|1155681_1156143_-|hypothetical-protein
MKLTLLLVIACIANTFAQLSPQVLDSLQQVKYIKAKYVLHASQNISLAPSRLYTLKGEKYYGEYVTKYNHRGSALEFYSGGSEGYIPHKRYNTYGKDLPFEADMYEYHIKIDKKHGTIIDNGETHRNFHFIKGEKKIKIPTNSQGRFIIYEYL
>NZ_CP022386.1|WP_095909992.1|1156608_1156989_-|large-conductance-mechanosensitive-channel-protein-MscL
MGFLKEFKEFAVKGNVVDLAIGVIIGGAFGAIVSSLVADVITPLLLTPAFKATGAENLQDLVWNGVAYGKFLAAVINFLCVAFVLFMLVKGINKFKKKEEPAPEAPAGPTQEELLAEIRDLLKKNN
>NZ_CP022386.1|WP_095909993.1|1157051_1157738_-|hypothetical-protein
MRNYILWISLFLGMVSYGQSDSLALDNKYLEDQFHIGISYDWVVSRPSGVRQHSFSRSLFGGYQRDIPLNKQRNIGFAAGVSYSYDLLYLNIQAKQIEGQMSYEIISISDKKVEDSYYEQHSIGFPIEFRWRTSTPYSHKFWRIYTGVKPTYTFASRYKFSGSEGSYSLSDPNLKGYMDAKLYIAVGHNTWNVYLQYALRPLFKGENSQNGQNLQSNILKIGLIFYIL
>NZ_CP022386.1|WP_002669315.1|1158016_1159003_+|porphobilinogen-synthase
MNILRRNRRLRVNETIRALVRETTITPNDFIVPLFVVEGLGIRAEIPSMPNYYRYSLDYLAQEVKELWSLGIKSVLLFVKVPDHLKDNEGTEAINPDGLMQRAIKTVKEATPDMLVMTDVALDPYSIYGHDGIIKNGVVENDTTVSILAQMSLSHVRAGADWVAPSDMMDGRIEQIRLFLDKYNYTNAGIMAYSAKYASALYGPFRDALDSAPVDEQDIPKDKKTYQMDYANRLEAIKEVIMDVEEGADMVMVKPGIVYLDVVREVKNAVNVPVSVYQVSGEYAMIKAAAQNGWLDHDAIMLEQIYAIKRAGADLIASYFAKDVVKLL
>NZ_CP022386.1|WP_095909994.1|1159107_1159998_+|exopolyphosphatase
MNIRKFAGIDIGSNGVRLLIANILEEEGKTPIFSKGSLVRVPIRLGADVFEQGRISAENASRLSDTMQAYHLLMKVQGVEAYRACATSAMREATNGTEIVREIAQHTGVQIEIIGGAEEAAIIANTDLHTLVESDKNYLYIDVGGGSTEFTIYSQGEVRAARSFPIGGVRLLKGKVDEQVWEELKEWIHIHTKGLKTIEAIGSGGNINKIFKVSGKRKDSPLSLHFLEDYLKEINSLSYEERIRDLELNPDRADILPLALPIYIKAMKWAKIKHILVPKVGLADGIVRQLYLSSEQ
>NZ_CP022386.1|WP_095909995.1|1160088_1161054_-|hydrogen-peroxide-inducible-genes-activator
MTIVQFQYILAVAQYKNFSVAAQKCFVTQPTLSMQVQRLEEELDVLIFDRAKKPLRVTEVGEKILQQAESIVSESERIKDIIAQHKGFIGGRFRLGIIPTVAPTLLPMFLNNFTKKYPKVELKVEEMTTRECIRELAEGTLDVAIVATPLHEKHLIERPLYYEPFVAYIPNAKYHLTENQKIQVSDLHLNDILMLQDGHCFRESVLNICQENSSSDKGKDNSLEIKSGSFETLIKLANEGMGMTLLPYLHTLDLSKEEKKNLHYFEEPSPAREISLLYHSNELKISIIDALYNVISGVIRGAITFENLNIIDPILKKKKKQ
>NZ_CP022386.1|WP_095909996.1|1161239_1162118_+|FtsX-like-permease-family-protein
MHTRTERYNRRKLISSYFSVTLSITLVLFLLGLLGFLLINVKNFTDSYKEHLIIHVFLKDTAKEADIEQLQKSLSLASYTKQVEFISKEQAAQSFSEEIGEDFISFIGDNPLENSFDLALKADYVTPQKMEEVKESILQNASVKEVNYDKDSVKKIHSNIQSISLVILAVSAIFTVVAMLLINASIRLSVYSKRFIIKTMQLVGATKAFIRRPFIITNIWLGILSAILACAALAFTFYAIDQSWPEWGLIMHYRDFIWVGAALFLIGVFLSWISTYFAAQRFLNLHTDELYY
>NZ_CP022386.1|WP_002669148.1|1162127_1162991_+|geranylgeranylglycerol-phosphate-geranylgeranyltransferase
MLPFEKFIGLFSVVRGYNIMMICIAQYLTAIFILSRQPLRQVLLDPRLFAIVLAGALAVAGGYIINAFYDQEKDLINKPTRTLMERMVGQHTKLSLYFILNFLSVIVASYVSFRAVLFFSIYIFMMWFYSHRIKKIVLVGNIVSGILSIIPFFAIFVYYHNFQKIIFVHAAFLYYLLLAKDFVKDLQNIKGDFALGYHTIATDYGERSSKQLITVLIGLTLVCIYFLTAFPDTGSMKYYFILTAIILLGGFLPILWKGRTQIHYAFLRNLLKVIIVVGVFCIALIRR

Crispr_ID: NZ_CP022386_8

• CRISPR_ID: NZ_CP022386_8
• CRISPR_location: 2699095-2699206
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP022386_8

Consensus_repeat	Method
CCAGCGAGTGCCCACAGCTGGGTATGTGGGGAAGAGTGAAGAA	CRISPRCasFinder

spacers of NZ_CP022386_8

>8.1|2699138|26|NZ_CP022386|CRISPRCasFinder
TGAAGAGTGAAAAGTGAAGAATGTAA

CRISPR arrays and Neighbor proteins around NZ_CP022386_8

CRISPR arrays

The CRISPR arrays of NZ_CP022386_8

>merge|NZ_CP022386|8|2699095-2699206|CRISPRCasFinder
CCAGCGAGTGCCCACAGCTGGGTATGTGGGGAAGAGTGAAGAATGAAGAGTGAAAAGTGAAGAATGTAACCAGCGAGTGCCCACAGCTGGGTATGTGGTGAAGAGTGAAGAA

>NZ_CP022386|8|8|2699095-2699206|CRISPRCasFinder
CCAGCGAGTGCCCACAGCTGGGTATGTGGGGAAGAGTGAAGAA	TGAAGAGTGAAAAGTGAAGAATGTAA
CCAGCGAGTGCCCACAGCTGGGTATGTGGTGAAGAGTGAAGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022386.1|WP_095911152.1|2701621_2702569_+|methionyl-tRNA-formyltransferase	unknown	unknown	gnl|CDD|234567
NZ_CP022386.1|WP_095911148.1|2698397_2699078_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|365877
NZ_CP022386.1|WP_095911150.1|2699545_2700127_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911155.1|2705314_2706391_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_CP022386.1|WP_095911154.1|2704141_2705203_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238744
NZ_CP022386.1|WP_002667689.1|2702721_2702994_+|HU-family-DNA-binding-protein	unknown	unknown	gnl|CDD|259853
NZ_CP022386.1|WP_095911147.1|2697450_2698368_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911142.1|2694749_2695193_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911141.1|2693304_2694747_+|oligosaccharide-flippase-family-protein	unknown	unknown	gnl|CDD|240533
NZ_CP022386.1|WP_095911144.1|2696072_2696351_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911146.1|2696909_2697437_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_002667727.1|2706374_2707034_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP022386.1|WP_095911145.1|2696350_2696797_+|PIN-domain-nuclease	unknown	unknown	gnl|CDD|227669
NZ_CP022386.1|WP_095911139.1|2691705_2692638_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911151.1|2700222_2701578_+|dNTP-triphosphohydrolase	unknown	unknown	gnl|CDD|234897
NZ_CP022386.1|WP_095911149.1|2699243_2699531_+|GTP-cyclohydrolase	unknown	unknown	gnl|CDD|225225
NZ_CP022386.1|WP_095911143.1|2695189_2695990_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911140.1|2692644_2693292_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP022386.1|WP_095911153.1|2703146_2704145_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238744
NZ_CP022386.1|WP_002667670.1|2707118_2707640_+|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP022386.1|WP_095911152.1|2701621_2702569_+|methionyl-tRNA-formyltransferase	gnl|CDD|234567	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed.	3.56755e-143
NZ_CP022386.1|WP_095911148.1|2698397_2699078_+|SDR-family-oxidoreductase	gnl|CDD|365877	pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.	3.63133e-54
NZ_CP022386.1|WP_002667727.1|2706374_2707034_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.80217e-107
NZ_CP022386.1|WP_095911155.1|2705314_2706391_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.5622e-34
NZ_CP022386.1|WP_095911154.1|2704141_2705203_+|VWA-domain-containing-protein	gnl|CDD|238744	cd01467, vWA_BatA_type, VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup are bacterial in origin. They are typified by the presence of a MIDAS motif.	5.04732e-47
NZ_CP022386.1|WP_002667689.1|2702721_2702994_+|HU-family-DNA-binding-protein	gnl|CDD|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	6.73358e-41
NZ_CP022386.1|WP_095911141.1|2693304_2694747_+|oligosaccharide-flippase-family-protein	gnl|CDD|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	5.42286e-21
NZ_CP022386.1|WP_095911145.1|2696350_2696797_+|PIN-domain-nuclease	gnl|CDD|227669	COG5378, COG5378, Predicted nucleotide-binding protein [General function prediction only].	5.09302e-12
NZ_CP022386.1|WP_095911151.1|2700222_2701578_+|dNTP-triphosphohydrolase	gnl|CDD|234897	PRK01096, PRK01096, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	2.0525e-135
NZ_CP022386.1|WP_095911149.1|2699243_2699531_+|GTP-cyclohydrolase	gnl|CDD|225225	COG2350, COG2350, Uncharacterized protein conserved in bacteria [Function unknown].	8.58057e-15
NZ_CP022386.1|WP_095911153.1|2703146_2704145_+|VWA-domain-containing-protein	gnl|CDD|238744	cd01467, vWA_BatA_type, VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses. In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup are bacterial in origin. They are typified by the presence of a MIDAS motif.	8.32961e-68
NZ_CP022386.1|WP_002667670.1|2707118_2707640_+|adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	5.83286e-88

Protein sequences

>NZ_CP022386.1|WP_095911148.1|2698397_2699078_+|SDR-family-oxidoreductase
MKNIIITGASRGIGFELVQQLASQGHNILALSRHTAPIEALKLPKVHCFPFDITLATDREAVAQFVKEQWKKVDILIHNAGKLINKPFEALTETDFLEVYKVNVFGVAHLTQQLLPFMEKGAHVVSISSMGGIQGSLKFGGLAAYSSSKGALITLSELLAEEYKERGIVFNTLALGAVQTEMLTEAFPDYKANITPQQMARYIANFALNGGEVFNGKVLQVANTTP
>NZ_CP022386.1|WP_095911147.1|2697450_2698368_+|hypothetical-protein
MIDITTLDLLRYMGQRPPMYIGEYDIFSLKAFLDGLAFQPKSEDEGLVFLQQVFYPWLKEKYALKEEQLWAQQLSLLCDTQEEAVHFFFTLFDECYKDYTSGHIKPCSPSPSSKVSYKEMTTIELMELIRENPSAYLSKYSLRCFNAFLGGYEIHQESDETDEELRDFEHWIQKRYSIFDTRGTIGILELVTETEGEALDKFFELWDIFRGKITEAPIELTPKQLEVKQRFIQGLQEVFRKGYDPGEIRRYTQLFSYDNWREAVALRDIIAALYWFSEEKEETFVQLVQKHLGIDIYQSITSEKK
>NZ_CP022386.1|WP_095911146.1|2696909_2697437_+|hypothetical-protein
MTSEEIKAIVYYIQGLQTLWKEGYNAEKVALYNYQFSLRAEMNMPDGLLDVIEMLEMWDDNWIYGAAPLTEKEASTIIQEELNIDIYHPEKDIIALVTNEFISQLKEECSSNIIIVKALENAQKLIAYDEYLLALQNILGELLTHHIRIPADILAIIDVVEDPHIRRLQASLWGI
>NZ_CP022386.1|WP_095911145.1|2696350_2696797_+|PIN-domain-nuclease
MIVIADSNIFYSSLITPNGTIAAILKDRNMQFLSPDYIIEEVKEHITDIQKRIKNTKTKKQLLEELKVLLERVKIIPLSSLAKKNIQKALTIVEDIDEDDYPFIAMYFQYKHRIWSRDKELILGMTEKGFGHFFISTDEIRGHLYKKN
>NZ_CP022386.1|WP_095911144.1|2696072_2696351_+|hypothetical-protein
MLMTFTINESHPQATALVELLKTFSFVSFKETKTKTKKTATKSKSTLVEAASEEESPEDYEFIMALSKETNRNVAHRLAKEKNIILPSQKKK
>NZ_CP022386.1|WP_095911143.1|2695189_2695990_+|hypothetical-protein
MTSEEIKATTKNILVIVSLFSLGFLYSQKKVVKYTDKQGWQQRILYYLTPQGKEYARVYRSLDKKDISRDSLAFYKTGIKLYTSDGYGYRLSSQIDYENPKKLKGEHFLLQHIRSVDSWDDLLYDNTLIKYLIGERKIKPNETFFDNQLKFETGIFGRSSYANYYSNTGLPFESDRNYKSIVWVKIQFNDKKKPIRLEFFLKKDSEIKDPLYKDFYYIREYFYKNEIVSEVVTTIKEVGGKTDKYTESYEVGALNQFSKSKNNYEK
>NZ_CP022386.1|WP_095911142.1|2694749_2695193_+|hypothetical-protein
MHPYIKNILENYTYPTIKSIAYPNGDMLVLQGQWLGEEYHLRILCQSTLDSYFKYNEADYVSNLYPQKVAENDQYEVYGGECSWEGDGFIYIINKESSELLWFLFLDNSEYFKEAYFEDTNHIIAHSELNLRLRIPINAPEKLSVIK
>NZ_CP022386.1|WP_095911141.1|2693304_2694747_+|oligosaccharide-flippase-family-protein
MGIVLRQSFKNVVATYLGFAIGALNTLFLFTYFLSKAQYGLVSYVTSTATILSPLIAFGVSNTWVRYYSAYTDRQEQGKLNLMLCLLPLLVILPATLLGSMAYEQIVQWLSAKNTEVRPYVWLIFLTAVAMAYFEIAYAWMRVQLKTVFGNFLKEVFHRVGVMLLLVAIYFGVIDFHQLMYGVFWVYALRMLLMFVSAFYVRRPTFAWGLPQGKNEVFLYSLFVILSGSVASVLMDIDKFMLNQYLPISEIAVYNVAIFTATVIAIPYRSMYQIVSPLTAQFMNQQKPQELADLYKRSTVNTYFVSMVICVLIVVNAQQCYALLPDKDYSTGLWVLIIISVVKLSDALVGFSNAVLLNSPYYRTVLFLGVFLVIGAVLMNRWLIPLYGINGAGVATLIAFSSYNLLKSVFVYRKYGLQPFYKETLQTTLFGLVAIGGFFFWDFPFHPLVNIGLKSLLVGVFWLWVLVKFRLSEDLTKILK
>NZ_CP022386.1|WP_095911140.1|2692644_2693292_+|hypothetical-protein
MNIEILAPYCTTAKQQKLLEKLRKKLSLKSSKDLQTVVELVECLFVSKQYEGLLAFLPEVLAVPFAANFNLWYPIERSFALIAEVPTITTEQRKACFLHFKSVTDYKGLPDFQDMYDYYFQDYLALYFLNNTLEYLQKSIAEKETSYEFSYRMNLIIDASRVKLINEEVDYKTLEFPKEDRQPTYNSREELQDYMNTLIAEQLTALQDKKFVKYY
>NZ_CP022386.1|WP_095911139.1|2691705_2692638_+|hypothetical-protein
MSIEQKDKEQLEQLIASEKYQQILGKLCDIIDMVFEEEMPSFTVLNYTHKALKDAGVTLEEIAPVALADDHFLNFSILKMDYIKSGKTMHFSKDFLIRNMIEFYFLKTNPKALPDYLKKAGLKNYMVPLKKWFTEATDTELVVAVSTSIKELKKKREKTEDTSSQTATREDWERLSAVYPKLTKQVLKDFDEYNVVTAGIPLAEITQKIQDLGVTFSEELTLFFQHIGELRLEGVEIRFTDLYTDVFNGKDYLVLGEFWKYGDGDKLLYAPDTQQIFCFAHEYAKPKVIKQADTMTEFVEKKLVAYLKNY
>NZ_CP022386.1|WP_095911149.1|2699243_2699531_+|GTP-cyclohydrolase
MYIIILTYQKDLSEVEKHLESHRAYLDKHYASGHFVASGAQVPRKGGVILCKAGSKEEILDIIAQDPFHEHRIAAYQIIEFTPTKFSEAFGKVLS
>NZ_CP022386.1|WP_095911150.1|2699545_2700127_+|hypothetical-protein
MDLQQLIKNFPWRRFGTPYETNANIVKQSIVKILDGAATEKDYQNLIYSFESQAWTIKLSPWGMRFYLALLEEDKADKAILLRDMLTLFEAANYSSQSPQAKDFKATKGKVAKYEAYKEKLFNDAYDGTMDEEFLKLVKSLDRHYYHVAIMELLEANVPLLQHFTTSEDKTIAQRATSLIEAIKHPKIYPINQ
>NZ_CP022386.1|WP_095911151.1|2700222_2701578_+|dNTP-triphosphohydrolase
MMDWQHLLSLRKQGDTKTRSREQEDPTRLSYDVDYDRIVFSGAFRSLQDKTQVIPLSGSGFVHTRLTHSMEVSVVGRSLGRAIGAKVLQKYPHLQELGYQMNDFGTIVASAALAHDIGNPPFGHSGEKAIGDFFRYHEGSLLKGQISDREYADLCSFEGNANGFKILTESRAGVQGGLRLTYATLGTFIKYPKESLPIKPSGAVYDKKYNIFQSDKAFFHEVAQELSLKAIVEGDALRYVRHPLAFLVEAADDICYTLIDFEDGINLGWIPEEHALEYLIQLIRGSKIKPENITEKYYQLSHKQDRIAYLRALSIGTLIGEAVALFEENEESLLRGDFTTSLLEKSKYKHQIKDIIDLSVSNIYQSPQVVEKELAGYAILQHLLRVYFTAVYHKWHGTTSSYDHIILKTVPTRYLLEEEELYEQILAITCYVASLTDTQTTKLHSKLNGIL
>NZ_CP022386.1|WP_095911152.1|2701621_2702569_+|methionyl-tRNA-formyltransferase
MKDLRIIFMGTPDFATGVLQRMVEEGLQVVAVVTVADKPAGRGQKLQESSVKKYALSQQIPVLQPISLRDEAFLAALKEFQADVQVVVAFRMLPKVVWQMPSKGTFNLHASLLPDYRGAAPINWAIIDGETTTGVTTFLIDDQIDTGAILLKEEVTIAPRETAGTLHDKLMTVGADLVVQTLALIASGQAVAKPQPKEVMPKEAPKIHKETSRIPWEKSLWEIDRFVRGMAPYPTAWALLHHQGEEYAVKIYEATPVDEPHTLKIGSIRLQHKKIEVAVRGGFLQIEILQFPSKKRMTAQEFLNGFHFTEGDFFA
>NZ_CP022386.1|WP_002667689.1|2702721_2702994_+|HU-family-DNA-binding-protein
MNKTELIDAIAQEAGLSKADAKKALEAFLATVEKTLKKGDKISLVGFGSWSVTEKAAREGRNPQTGKTIKIPAKKVVKFKAGTELSNAVN
>NZ_CP022386.1|WP_095911153.1|2703146_2704145_+|VWA-domain-containing-protein
MKDITFVNPEFFWLFLLFPLLVGWLWIGRKKEIPSVLFSSLQGVRSVPTWRTRLRPILYILRGLSLVCLIIALARPRSSSEITKTKTTEGIDIILSIDMSSSMLAKDLKPNRIEALKRVAAQFIQQRASDRIGIVVYSGESYTKVPATTDKSIVLQALKEIRQGEIEDGTAIGMGLGTAINRLKDSKTKSKVIILMTDGVNNTGVIDPLSAAELAKEYGIRVYTIGIGTNGKALSPVAYNPDGSFQYDMVPVEIDEKLLAEISKITGGQYFRATDNNKLAQIYTEIDKLEKSKIEELKYYQHQENFRLWAILALVFLVGEFGLRHTIFRSFV
>NZ_CP022386.1|WP_095911154.1|2704141_2705203_+|VWA-domain-containing-protein
MIHIEEKIYFYLLLLLPLIVLLYFGVQFWKAKASKHFAQKATFARLVPQRSFFKPWVKLVFFALVFVFIVIALANPKVGTKLETVKREGVDIVFAIDVSKSMLAEDVKPNRIEKAKHIISQLIEVLHGDRVAFIPYAAQAYPQLPLTSDYSSAKIFLEGINTNMLSSQGTAIGEAIQMAINYFEESSQTSKILIILSDGEDHQQGVDTVIQEAKDKGIRLFTIGLGTAQGATIPVSENGQIVAKRDNNGQVVITKLNQALLEEIAQEGGGKYFNGANTKEVLDALQKALDTIEKNEYESQVFSDYKDQFQWFLAIAFALLAIDIFISYKKTSWVRRLNLFGEREKVEVRRSEK
>NZ_CP022386.1|WP_095911155.1|2705314_2706391_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKRKKILFILALLVLGILAYFWFSQSAPKVTTPTTSIENRDIKEEIYIPGNVYPVKEIELKSQLSGVLDKIFVKIGDVVQEGSPVASISLVPSTLELERLENNVKMAQINYDAAKLSYERSQKLFQAQTISQAAMESAQREYGTAREQLLSAQNQLAIQKTGKVVGKKETSNIVKSSISGTVIDLPLEEGASVIERNTLNSGITVAILAKMGQFIFRTQLAEQYLENIHLGDSISLAFNAYKDLNTKAKITKISSKGTLENGIMKYTLEAEFPVNSQMPVIRSGYSATAEIVLSSKKNVPSIEEKYITYRNDSTYVWVKKGEKIEKKYIELGISDGKYTEITQGLTKDDKIVQNDSAN
>NZ_CP022386.1|WP_002667727.1|2706374_2707034_+|ABC-transporter-ATP-binding-protein
MIQLTDIKKAYRTEYDTLQVLKGINLEIEKGEMVSIMGASGSGKSTLMNIIGLLDTYDSGTYLFDNKDMKNLDSIERSAYRSRNIGFVFQAANLISYKNVVENVALPLFYQNVSKKEREQKAMEKLEPLGIANWAKHFPNELSGGQRQRVAIARALIADAPLLLADEPTGQLDSKTTNEVMQIFKEINQRGTTIVIVTHEEDIAAQTQRIIRIVDGLIQ
>NZ_CP022386.1|WP_002667670.1|2707118_2707640_+|adenine-phosphoribosyltransferase
MNDIEIEDFVRNVYDFPKKGVVFKDITPLLRNPQITQKVLQQLIEPLKGLKIDKVAGIESRGFLFGMLLAQALQVGFIPVRKPGKLPAETISESYDLEYGHSSLEIHTDAILQGEKVLVHDDVLATGGTALAAAKLVERLGGEVVRCSFLMEIAFLKGREKLHKYQINSILNY

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP022386_8	8.1|2699138|26|NZ_CP022386|CRISPRCasFinder	2699138-2699163	26	NZ_CP022386.1	582762-582787	2	0.923
NZ_CP022386_8	8.1|2699138|26|NZ_CP022386|CRISPRCasFinder	2699138-2699163	26	NZ_CP022386.1	1113434-1113459	2	0.923
NZ_CP022386_8	8.1|2699138|26|NZ_CP022386|CRISPRCasFinder	2699138-2699163	26	NZ_CP022386.1	1171480-1171505	2	0.923
NZ_CP022386_8	8.1|2699138|26|NZ_CP022386|CRISPRCasFinder	2699138-2699163	26	NZ_CP022386.1	1199601-1199626	2	0.923
NZ_CP022386_8	8.1|2699138|26|NZ_CP022386|CRISPRCasFinder	2699138-2699163	26	NZ_CP022386.1	1202817-1202842	2	0.923

1. spacer 8.1|2699138|26|NZ_CP022386|CRISPRCasFinder matches to position: 582762-582787, mismatch: 2, identity: 0.923

tgaagagtgaaaagtgaagaatgtaa	CRISPR spacer
tgaagagtgaaaagtgaagagtgaaa	Protospacer
********************.** **

2. spacer 8.1|2699138|26|NZ_CP022386|CRISPRCasFinder matches to position: 1113434-1113459, mismatch: 2, identity: 0.923

tgaagagtgaaaagtgaagaatgtaa	CRISPR spacer
tgaagaatgaaaagtgaagaatgaaa	Protospacer
******.**************** **

3. spacer 8.1|2699138|26|NZ_CP022386|CRISPRCasFinder matches to position: 1171480-1171505, mismatch: 2, identity: 0.923

tgaagagtgaaaagtgaagaatgtaa	CRISPR spacer
tgaaaagtgaaaagtgaagaatgaaa	Protospacer
****.****************** **

4. spacer 8.1|2699138|26|NZ_CP022386|CRISPRCasFinder matches to position: 1199601-1199626, mismatch: 2, identity: 0.923

tgaagagtgaaaagtgaagaatgtaa	CRISPR spacer
tgaagagtgaaaagtgaagagtgaaa	Protospacer
********************.** **

5. spacer 8.1|2699138|26|NZ_CP022386|CRISPRCasFinder matches to position: 1202817-1202842, mismatch: 2, identity: 0.923

tgaagagtgaaaagtgaagaatgtaa	CRISPR spacer
tgaagagtgaaaagtgaagagtgaaa	Protospacer
********************.** **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MK524494	Mycobacterium phage Rabbs, complete genome	19498-19527	5	0.833
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NC_031102	Mycobacterium phage Sneeze, complete genome	19497-19526	5	0.833
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	279825-279854	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	138735-138764	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	101309-101338	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	741686-741715	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP047181	Rathayibacter festucae strain VKM Ac-2802 plasmid unnamed1, complete sequence	9330-9359	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP047184	Rathayibacter sp. VKM Ac-2801 plasmid unnamed, complete sequence	6505-6534	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	488372-488401	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1416786-1416815	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP024200	Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence	410403-410432	6	0.8
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KC787107	Mycobacterium phage Bo4, complete genome	19882-19911	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KJ725374	Mycobacterium phage Guo1, complete genome	14410-14439	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KC787109	Mycobacterium phage Legendre, partial genome	21298-21327	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH371116	Mycobacterium phage DMoney, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH045569	Mycobacterium phage Schiebel, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH371119	Mycobacterium phage OctaviousRex, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MF919497	Mycobacterium phage Chance64, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH001456	Mycobacterium phage CLED96, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	GQ303261	Mycobacterium phage Hope, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MG099946	Mycobacterium phage LouisV14, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KC787112	Mycobacterium phage Clark, partial genome	18701-18730	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH779513	Mycobacterium phage Olga, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MK919475	Mycobacterium phage Camri, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MK310146	Mycobacterium phage Crespo, complete genome	19413-19442	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MK524493	Mycobacterium phage Darionha, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	EU568876	Mycobacterium phage BPs, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MF668268	Mycobacterium phage Aroostook, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KX588251	Mycobacterium phage Jane, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KC787103	Mycobacterium phage Chy2, partial genome	18176-18205	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH001455	Mycobacterium phage Remy19, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KT355472	Mycobacterium phage Cedasite, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KX664455	Mycobacterium phage Zombie, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH077584	Mycobacterium phage Phish, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KC787108	Mycobacterium phage DNAIII, complete genome	19421-19450	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MN444875	Mycobacterium phage Jonghyun, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MK433279	Mycobacterium phage Kareem, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MT818422	Mycobacterium phage Periodt, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MK305884	Mycobacterium phage BQuat, complete genome	19403-19432	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MF668272	Mycobacterium phage Gideon, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH779515	Mycobacterium phage Sweets, complete genome	19407-19436	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KC787104	Mycobacterium phage Chy3, partial genome	19791-19820	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NC_012788	Mycobacterium phage Angel, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KX443326	Mycobacterium phage BruceB, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MK433277	Mycobacterium phage Renaissance, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH590605	Mycobacterium phage Cherrybomb426, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH779509	Mycobacterium phage Kasen3, complete genome	19413-19442	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	JN699002	Mycobacterium phage Avrafan, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH779507	Mycobacterium phage Hotshotbaby7, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KT355474	Mycobacterium phage Frosty24, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	JN412593	Mycobacterium phage Liefie, complete genome	19411-19440	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH479920	Mycobacterium phage Mowgli, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NC_008202	Mycobacterium phage Halo, complete genome	19407-19436	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KM923970	Mycobacterium phage Gomashi, complete genome	19413-19442	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	MH450127	Mycobacterium phage Plagueis, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KT347314	Mycobacterium phage Phreak, complete genome	19412-19441	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KT365399	Mycobacterium phage Annihilator, complete genome	19403-19432	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	KC787110	Mycobacterium phage Leo, complete genome	19428-19457	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NC_020553	Corynebacterium callunae DSM 20147 plasmid pCC2, complete sequence	1947-1976	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP021915	Sagittula sp. P11 plasmid unnamed2, complete sequence	154656-154685	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP010856	Marinovum algicola DG 898 plasmid pMaD1, complete sequence	158211-158240	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP018081	Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence	108908-108937	7	0.767
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	212994-213023	7	0.767
NZ_CP022386_3	3.8|349310|29|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349310-349338	29	KX961630	Bacillus phage QCM8, complete genome	149355-149383	7	0.759
NZ_CP022386_3	3.8|349310|29|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349310-349338	29	NZ_CP012101	Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence	240140-240168	7	0.759
NZ_CP022386_1	1.1|174090|33|NZ_CP022386|CRISPRCasFinder	174090-174122	33	NZ_CP020859	Lactobacillus salivarius strain ZLS006 plasmid unnamed1, complete sequence	164349-164381	8	0.758
NZ_CP022386_3	3.6|349160|30|NZ_CP022386|CRISPRCasFinder,CRT	349160-349189	30	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	59604-59633	8	0.733
NZ_CP022386_3	3.6|349160|30|NZ_CP022386|CRISPRCasFinder,CRT	349160-349189	30	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	70320-70349	8	0.733
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	590788-590817	8	0.733
NZ_CP022386_3	3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR	349235-349264	30	NZ_CP053905	Hymenobacter sp. BRD67 plasmid unnamed1, complete sequence	67008-67037	8	0.733
NZ_CP022386_3	3.5|349085|30|NZ_CP022386|CRISPRCasFinder,CRT	349085-349114	30	JQ011317	Escherichia phage TL-2011b, complete genome	25641-25670	9	0.7
NZ_CP022386_4	4.1|389317|33|NZ_CP022386|CRISPRCasFinder	389317-389349	33	NC_018084	Clostridium phage phiZP2, complete genome	8914-8946	9	0.727
NZ_CP022386_4	4.1|389317|33|NZ_CP022386|CRISPRCasFinder	389317-389349	33	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	813737-813769	9	0.727

1. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MK524494 (Mycobacterium phage Rabbs, complete genome) position: , mismatch: 5, identity: 0.833

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
ggacccatctcgccctgctcgccctgcggg	Protospacer
 .* ***********. *************

2. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NC_031102 (Mycobacterium phage Sneeze, complete genome) position: , mismatch: 5, identity: 0.833

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
ggacccatctcgccctgctcgccctgcggg	Protospacer
 .* ***********. *************

3. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
acgacgatctcgccccgctcgccctgcggc	Protospacer
  .** ********** ************ 

4. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
acgacgatctcgccccgctcgccctgcggc	Protospacer
  .** ********** ************ 

5. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
acgacgatctcgccccgctcgccctgcggc	Protospacer
  .** ********** ************ 

6. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
acgacgatctcgccccgctcgccctgcggc	Protospacer
  .** ********** ************ 

7. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047181 (Rathayibacter festucae strain VKM Ac-2802 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
ccgaaactctctcccccctcgccctgcggg	Protospacer
* .*   **** ******************

8. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047184 (Rathayibacter sp. VKM Ac-2801 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
ccgaaactctctcccccctcgccctgcggg	Protospacer
* .*   **** ******************

9. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
cccaccatctcgccgccctcgcccggcacg	Protospacer
*  *********** ********* **. *

10. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.8

caaaccat---ctcgcccccctcgccctgcggg	CRISPR spacer
---accgtgccctcgccccactcgccctgcggc	Protospacer
   ***.*   ******** ************ 

11. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024200 (Thalassospira marina strain CSC3H3 plasmid pCSC3H3, complete sequence) position: , mismatch: 6, identity: 0.8

--caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gccaaa--atctcgccaccctcgccctgcaac	Protospacer
  ****  ******** ************.. 

12. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KC787107 (Mycobacterium phage Bo4, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

13. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KJ725374 (Mycobacterium phage Guo1, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

14. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KC787109 (Mycobacterium phage Legendre, partial genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

15. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH371116 (Mycobacterium phage DMoney, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

16. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH045569 (Mycobacterium phage Schiebel, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

17. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH371119 (Mycobacterium phage OctaviousRex, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

18. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MF919497 (Mycobacterium phage Chance64, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

19. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH001456 (Mycobacterium phage CLED96, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

20. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to GQ303261 (Mycobacterium phage Hope, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

21. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MG099946 (Mycobacterium phage LouisV14, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

22. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KC787112 (Mycobacterium phage Clark, partial genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

23. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH779513 (Mycobacterium phage Olga, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

24. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MK919475 (Mycobacterium phage Camri, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

25. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MK310146 (Mycobacterium phage Crespo, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

26. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MK524493 (Mycobacterium phage Darionha, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

27. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to EU568876 (Mycobacterium phage BPs, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

28. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MF668268 (Mycobacterium phage Aroostook, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

29. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KX588251 (Mycobacterium phage Jane, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

30. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KC787103 (Mycobacterium phage Chy2, partial genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

31. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH001455 (Mycobacterium phage Remy19, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

32. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KT355472 (Mycobacterium phage Cedasite, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

33. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KX664455 (Mycobacterium phage Zombie, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

34. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH077584 (Mycobacterium phage Phish, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

35. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KC787108 (Mycobacterium phage DNAIII, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

36. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MN444875 (Mycobacterium phage Jonghyun, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

37. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MK433279 (Mycobacterium phage Kareem, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

38. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MT818422 (Mycobacterium phage Periodt, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

39. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MK305884 (Mycobacterium phage BQuat, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

40. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MF668272 (Mycobacterium phage Gideon, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

41. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH779515 (Mycobacterium phage Sweets, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

42. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KC787104 (Mycobacterium phage Chy3, partial genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

43. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NC_012788 (Mycobacterium phage Angel, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

44. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KX443326 (Mycobacterium phage BruceB, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

45. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MK433277 (Mycobacterium phage Renaissance, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

46. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH590605 (Mycobacterium phage Cherrybomb426, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

47. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH779509 (Mycobacterium phage Kasen3, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

48. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to JN699002 (Mycobacterium phage Avrafan, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

49. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH779507 (Mycobacterium phage Hotshotbaby7, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

50. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KT355474 (Mycobacterium phage Frosty24, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

51. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to JN412593 (Mycobacterium phage Liefie, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

52. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH479920 (Mycobacterium phage Mowgli, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

53. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NC_008202 (Mycobacterium phage Halo, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

54. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KM923970 (Mycobacterium phage Gomashi, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

55. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to MH450127 (Mycobacterium phage Plagueis, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

56. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KT347314 (Mycobacterium phage Phreak, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

57. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KT365399 (Mycobacterium phage Annihilator, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

58. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KC787110 (Mycobacterium phage Leo, complete genome) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gggcccatctcgccctgctcgccctgcgga	Protospacer
 .. ***********. ************.

59. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NC_020553 (Corynebacterium callunae DSM 20147 plasmid pCC2, complete sequence) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
cgctgtatctcgccgccctcgccctggggg	Protospacer
*.   .******** *********** ***

60. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021915 (Sagittula sp. P11 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

---caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gtgcag---atctcgccgacctcgccctgcggc	Protospacer
   **.   ********  ************* 

61. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010856 (Marinovum algicola DG 898 plasmid pMaD1, complete sequence) position: , mismatch: 7, identity: 0.767

---caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gtgcag---atctcgccgacctcgccctgcggc	Protospacer
   **.   ********  ************* 

62. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018081 (Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.767

---caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
gtgcag---atctcgccgacctcgccctgcggc	Protospacer
   **.   ********  ************* 

63. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 7, identity: 0.767

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
tggacgagatcacccccctcgccctgcggg	Protospacer
...** *  **.******************

64. spacer 3.8|349310|29|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to KX961630 (Bacillus phage QCM8, complete genome) position: , mismatch: 7, identity: 0.759

gtaatactctgtaccttttttatcgtaaa	CRISPR spacer
ttaatactctgtatcttttttatttatat	Protospacer
 ************.*********.   * 

65. spacer 3.8|349310|29|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012101 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence) position: , mismatch: 7, identity: 0.759

gtaatactctgtaccttttttatcgtaaa	CRISPR spacer
ttctaactctgttacttttttatcgtaat	Protospacer
 *   *******  ************** 

66. spacer 1.1|174090|33|NZ_CP022386|CRISPRCasFinder matches to NZ_CP020859 (Lactobacillus salivarius strain ZLS006 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

ttctaattgttaattatttaattatgactcttg	CRISPR spacer
ttctaattgctaataatttaattattaaaaata	Protospacer
*********.**** ********** *    *.

67. spacer 3.6|349160|30|NZ_CP022386|CRISPRCasFinder,CRT matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaattcctttatgagttcataataggaat	CRISPR spacer
ttaattcctttattagttaataattttttt	Protospacer
.************ **** *****     *

68. spacer 3.6|349160|30|NZ_CP022386|CRISPRCasFinder,CRT matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaattcctttatgagttcataataggaat	CRISPR spacer
ttaattcctttattagttaataattttttt	Protospacer
.************ **** *****     *

69. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 8, identity: 0.733

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
tcggccatctcgccccgctcgcccagcccg	Protospacer
. ..************ ******* **  *

70. spacer 3.7|349235|30|NZ_CP022386|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053905 (Hymenobacter sp. BRD67 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

caaaccatctcgcccccctcgccctgcggg	CRISPR spacer
ttctcaatcttgcccccctcgccctgctcg	Protospacer
.   * ****.****************  *

71. spacer 3.5|349085|30|NZ_CP022386|CRISPRCasFinder,CRT matches to JQ011317 (Escherichia phage TL-2011b, complete genome) position: , mismatch: 9, identity: 0.7

cagggtggtctacttttccacctattgtct	CRISPR spacer
tgcttgggtctaatttttcacctattgtca	Protospacer
..    ****** ****.*********** 

72. spacer 4.1|389317|33|NZ_CP022386|CRISPRCasFinder matches to NC_018084 (Clostridium phage phiZP2, complete genome) position: , mismatch: 9, identity: 0.727

ccaatacaaccaaacttatattttaattcatcg	CRISPR spacer
ataatacaatcaaacatatattttaatggaaat	Protospacer
 .*******.***** ***********  *   

73. spacer 4.1|389317|33|NZ_CP022386|CRISPRCasFinder matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 9, identity: 0.727

ccaatacaaccaaacttatattttaattcatcg	CRISPR spacer
ccaataaaaccaaatttatattttttttgcata	Protospacer
****** *******.*********  **   ..