CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP023411	Clostridium perfringens strain LLY_N11 plasmid pLLY_N11_1, complete sequence	0 crisprs	NA	0	0
NZ_CP023410	Clostridium perfringens strain LLY_N11 chromosome, complete genome	3 crisprs	csa3,cas14j,DEDDh,cas3,DinG,cas2,cas5,cas7,cas8b2,cas6,WYL,RT,csx1	10	4
NZ_CP023413	Clostridium perfringens strain LLY_N11 plasmid pLLY_N11_3, complete sequence	0 crisprs	NA	0	7
NZ_CP023412	Clostridium perfringens strain LLY_N11 plasmid pLLY_N11_2, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP023410_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023410_1

929988-930100

Orphan

Consensus_repeat	Method
TTATGTAAAGTAATAAATTTAAATAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP023410_1

>merge|NZ_CP023410|1|929988-930100|CRISPRCasFinder
TTATGTAAAGTAATAAATTTAAATAGAAGAGAAGAAGAGGTCTCCAAAAAAGATTTATTATTTTAAAAATAATTAGAATAATTTCTTATGTAAAGTAATAGATTTAAATAGAA

>NZ_CP023410|1|1|929988-930100|CRISPRCasFinder
TTATGTAAAGTAATAAATTTAAATAGAA	GAGAAGAAGAGGTCTCCAAAAAAGATTTATTATTTTAAAAATAATTAGAATAATTTC
TTATGTAAAGTAATAGATTTAAATAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023410.1\|WP_011590964.1\|926973_927384_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_003458682.1\|933599_934157_+\|stage-III-sporulation-protein-AF	unknown	unknown	gnl\|CDD\|131942
NZ_CP023410.1\|WP_003458694.1\|924583_925603_+\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|224376
NZ_CP023410.1\|WP_003451187.1\|935892_936300_+\|transcription-antitermination-factor-NusB	unknown	unknown	gnl\|CDD\|234686
NZ_CP023410.1\|WP_003458668.1\|926690_926987_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_003451336.1\|934171_934777_+\|stage-III-sporulation-protein-AG	unknown	unknown	gnl\|CDD\|274319
NZ_CP023410.1\|WP_057231743.1\|930115_931000_+\|stage-III-sporulation-protein-AA	unknown	unknown	gnl\|CDD\|274324
NZ_CP023410.1\|WP_003458726.1\|927358_927970_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_003451410.1\|935384_935774_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|377129
NZ_CP023410.1\|WP_003451536.1\|934802_935300_+\|stage-III-sporulation-protein-AH	unknown	unknown	gnl\|CDD\|378918
NZ_CP023410.1\|WP_003458684.1\|932419_933592_+\|stage-III-sporulation-protein-AE	unknown	unknown	gnl\|CDD\|213743
NZ_CP023410.1\|WP_003458718.1\|929555_929918_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_003458656.1\|926043_926556_+\|type-II-secretion-system-protein	unknown	unknown	gnl\|CDD\|225076
NZ_CP023410.1\|WP_003458670.1\|931146_931662_+\|stage-III-sporulation-protein-SpoAB	unknown	unknown	gnl\|CDD\|131880
NZ_CP023410.1\|WP_003458702.1\|925595_926024_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|236714
NZ_CP023410.1\|WP_003451649.1\|928884_929442_+\|elongation-factor-P	unknown	unknown	gnl\|CDD\|234788
NZ_CP023410.1\|WP_003451406.1\|932022_932409_+\|stage-III-sporulation-protein-AD	unknown	unknown	gnl\|CDD\|131896
NZ_CP023410.1\|WP_003481876.1\|927929_928370_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_011590962.1\|928366_928714_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_003451671.1\|931737_931935_+\|stage-III-sporulation-protein-AC	unknown	unknown	gnl\|CDD\|131895

Protein	Function_ID	Function_description	E-value
NZ_CP023410.1\|WP_003458694.1\|924583_925603_+\|type-II-secretion-system-F-family-protein	gnl\|CDD\|224376	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion].	2.38181e-53
NZ_CP023410.1\|WP_003451187.1\|935892_936300_+\|transcription-antitermination-factor-NusB	gnl\|CDD\|234686	PRK00202, nusB, transcription antitermination factor NusB.	2.5545e-50
NZ_CP023410.1\|WP_003458684.1\|932419_933592_+\|stage-III-sporulation-protein-AE	gnl\|CDD\|213743	TIGR02829, Stage_III_sporulation_protein_AE, stage III sporulation protein AE. A comparative genome analysis of all sequenced genomes of shows a number of proteins conserved strictly among the endospore-forming subset of the Firmicutes. This protein, a member of this panel, is found in a spore formation operon and is designated stage III sporulation protein AE. [Cellular processes, Sporulation and germination].	3.04994e-149
NZ_CP023410.1\|WP_003458702.1\|925595_926024_+\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|236714	PRK10557, PRK10557, prepilin peptidase-dependent protein.	0.00245866
NZ_CP023410.1\|WP_003451410.1\|935384_935774_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	5.69298e-30
NZ_CP023410.1\|WP_003451536.1\|934802_935300_+\|stage-III-sporulation-protein-AH	gnl\|CDD\|378918	pfam12685, SpoIIIAH, SpoIIIAH-like protein. Stage III sporulation protein AH (SpoIIIAH) is a protein that is involved in forespore engulfment. It forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling. This family of proteins is found in bacteria, archaea and eukaryotes and so must have a wider function that in sporulation. Proteins in this family are typically between 174 and 223 amino acids in length.	3.45938e-23
NZ_CP023410.1\|WP_003458656.1\|926043_926556_+\|type-II-secretion-system-protein	gnl\|CDD\|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	0.000623571
NZ_CP023410.1\|WP_003458670.1\|931146_931662_+\|stage-III-sporulation-protein-SpoAB	gnl\|CDD\|131880	TIGR02833, Stage_III_sporulation_protein_AB, stage III sporulation protein AB. A comparative genome analysis of all sequenced genomes of shows a number of proteins conserved strictly among the endospore-forming subset of the Firmicutes. This protein, a member of this panel, is designated stage III sporulation protein AB. [Cellular processes, Sporulation and germination].	1.85407e-76
NZ_CP023410.1\|WP_057231743.1\|930115_931000_+\|stage-III-sporulation-protein-AA	gnl\|CDD\|274324	TIGR02858, Stage_III_sporulation_protein_AA, stage III sporulation protein AA. Members of this protein are the stage III sporulation protein AA, encoded by one of several genes in the spoIIIA locus. It seems that this protein is found in a species if and only if that species is capable of endospore formation. [Cellular processes, Sporulation and germination].	1.50843e-160
NZ_CP023410.1\|WP_003451649.1\|928884_929442_+\|elongation-factor-P	gnl\|CDD\|234788	PRK00529, PRK00529, elongation factor P; Validated.	2.22205e-107
NZ_CP023410.1\|WP_003451406.1\|932022_932409_+\|stage-III-sporulation-protein-AD	gnl\|CDD\|131896	TIGR02849, Stage_III_sporulation_protein_AD, stage III sporulation protein AD. Members of this family are the uncharacterized protein SpoIIIAD, part of the spoIIIA operon that acts at sporulation stage III as part of a cascade of events leading to endospore formation. Note that the start sites of members of this family as annotated tend to be variable; quite a few members have apparent homologous protein-coding regions continuing upstream of the first available start codon. The length of the alignment and the scoring cutoff thresholds for the model have been set to try to detect all valid members of the family, even if annotation of the start site begins too far downstream. [Cellular processes, Sporulation and germination].	5.58273e-33
NZ_CP023410.1\|WP_003458682.1\|933599_934157_+\|stage-III-sporulation-protein-AF	gnl\|CDD\|131942	TIGR02896, Stage_III_sporulation_protein_AF, stage III sporulation protein AF. This family represents the stage III sporulation protein AF of the bacterial endospore formation program, which exists in some but not all members of the Firmicutes (formerly called low-GC Gram-positives). The C-terminal region of this protein is poorly conserved, so only the N-terminal region, which includes two predicted transmembrane domains, is included in the seed alignment. [Cellular processes, Sporulation and germination].	5.28448e-24
NZ_CP023410.1\|WP_003451336.1\|934171_934777_+\|stage-III-sporulation-protein-AG	gnl\|CDD\|274319	TIGR02830, Stage_III_sporulation_protein_AG, stage III sporulation protein AG. CC A comparative genome analysis of all sequenced genomes of shows a number of proteins conserved strictly among the endospore-forming subset of the Firmicutes. This protein, a member of this panel, is found in a spore formation operon and is designated stage III sporulation protein AG. [Cellular processes, Sporulation and germination].	2.26928e-69
NZ_CP023410.1\|WP_003451671.1\|931737_931935_+\|stage-III-sporulation-protein-AC	gnl\|CDD\|131895	TIGR02848, Stage_III_sporulation_protein_AC, stage III sporulation protein AC. Members of this protein family are designated SpoIIIAC, part of the spoIIIA operon of sporulation genes whose mutant phenotype is linked to sporulation stage III. Members of this family are encoded by the genome of a species if and only if that species is capable of endospore formation, as in Bacillus subtilis. The molecular function of this small, probable integral membrane protein is unknown. [Cellular processes, Sporulation and germination].	1.97477e-14

>NZ_CP023410.1|WP_003458718.1|929555_929918_+|hypothetical-protein
MKDIKNNISNLLKAMDKNTELDKEFKDSLLNVISSLVDKIEELQVNVETLDENVNLLNDDLSGVQDELFEELTLEELEEYDDEYCEVVCDKCHKPIYIEKDILNRSESIPCPYCGNEFEV
>NZ_CP023410.1|WP_003451649.1|928884_929442_+|elongation-factor-P
MISGSDLRKGTTFELDGQVYTVIDFLHVKPGKGAAFVRTKLRNVIMGGVTDRTFNPTDKLQEAIIERKEMQYLYSDGELYYFMDQETFEQIPLNHEKVEDAIKFLKENMNAVIKFYKGEAFSVEAPNFVELLITECEPSVKGNTATTAMKTAVVETGATVMVPMFVEEGNTIRIDTRTGEYMERV
>NZ_CP023410.1|WP_011590962.1|928366_928714_+|hypothetical-protein
MKKLKLDVTLATIFIVILLVQGIELFQLRNYEIPVLTNSIGEMDLNTVLKNIENKDCTVLQLEYKEGWIGKVLFTGSLEDLSNYVNLLKNNNINIKNYKIEKSEELRCFLDLKVV
>NZ_CP023410.1|WP_003481876.1|927929_928370_+|hypothetical-protein
MRLEVRRIYIKKYKNFLPIEYVEEYNRKIKKKLNIYILLLLLFNLFFYGKIKTENNKIKNYLSEIKGVNRERSLDKEFLEDINKLKEIIKDEKILNLSLERKSFEVEVNSIYKNSLINYINKINGRVYDISLNESNNTYRLKGELR
>NZ_CP023410.1|WP_003458726.1|927358_927970_+|hypothetical-protein
MLIKTLVINDTNDISKLKELKDKRVKIILLNEKIFIETLRVDKKCNIEEKIEQLIRDRFFNYTPLVHYEVLKYKKSLFLIVYFIGCDERFKSLLYERKDFALTFPELKNKNILSFKKATFELKNLKISIYIKGKLVLLKSVKDSNIIEVIEESLKGLEKDFGVSLKDFTFKIQKEYLKEEIKEWFKGLKLNEIRGEENLYQKI
>NZ_CP023410.1|WP_011590964.1|926973_927384_+|hypothetical-protein
MKRRKGFVSIEVMLVSLICSMIVTILMDNSFQRRKELDRSFKIISSNIDKNNSEEQFLKYMLKEKILNIDNINKLDFTLNNMNATYIEDKKAIHIKSKDKISGVFKDTYYGIDFRNDDIILSKRGNYEFVNKDLSN
>NZ_CP023410.1|WP_003458668.1|926690_926987_+|hypothetical-protein
MYLNHRFWDNMVENIKINKDKNYILVKFWRDGIVAEDKIEKIKNKLYVYYNYTGYGRNYSPALIEDVEKFDLMEKGNLFYIKLKVKNQEERIYCYEKA
>NZ_CP023410.1|WP_003458656.1|926043_926556_+|type-II-secretion-system-protein
MEDKINKKKGYLLVDMVLALALISILFLGIGKSYSTYIKNNYYIKEKIKVAEIINSLAMELKHNISFEDLRSINSGTYKISSLKINDLINSDIKEFLRKNLILHNKNHNDLGWTINISHFDQYESIINIIYKNEKPYISENKEVKIYKFLEKSFQNLENPPQKEEEKHIY
>NZ_CP023410.1|WP_003458702.1|925595_926024_+|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MYRKRKGFTLSEVIIYLAITSLILAIPTSFMIIKDRGYELKVEGEISKIHDFLMEAKQLSKKDNLYGEIIFDILDNKLIYENALRTTSLKLNEVKVSFNRDNLITINETGMISISGTITIIDKNNKRREITIVPGIWKINVK
>NZ_CP023410.1|WP_003458694.1|924583_925603_+|type-II-secretion-system-F-family-protein
MFGFKDEASYICLNLSTYVKSGMPIGRSLDLIKNTVKDKKYKESLKRIEKKVLNGEALSKAFKEEGNLYPDLMKDMMKIGEESGNLEEVLEKCARNILAEKEIKNKIIKSLRYPISLLIGLIIMIFGYVTYILPQFVDMYELRGIEGSKIMTLLNNYINFVEENPNVEVIVFCYFSCVLISLYLFFKVIPSEKILEKIEVYRMYYEIRILFLISMILNSGISLNNSLSVFGESLSDVKLRKYIKSINEELIKGTTLSSSIGKINVISHVSKGFLITGEESGLFSKNIEELLKIREKDFDRALNKTVGKIEPAMFIILGFVISAMMLLVLVPTFEGMKYV
>NZ_CP023410.1|WP_057231743.1|930115_931000_+|stage-III-sporulation-protein-AA
MKEIFDVLPDKINSCLKDKSNLNKLQEIRVKVGKPLNIVLDNTETIFNYVIRREDVKAIIQKISNYSLYAFEEDIRQGYITIQGGHRVGLAGQCVIEDNSIKTIRNITFLNIRVCREIVGCSNSLMNSLVENNRVNNTLIISPPKCGKTTLLRDITRNISNGISQIGFKGKRTVVIDERSEIAACYNGIPQMNVGMRTDVYDNCIKSEGMMMAVRGLSPEVIICDEIGTYKDMEGLMMAYNSGVSIIATLHGRNVEELYRRPVFREIVENNIINKVVVLSGKKGIGTIEGIYNV
>NZ_CP023410.1|WP_003458670.1|931146_931662_+|stage-III-sporulation-protein-SpoAB
MKVFFLLIIVLLSSLIGYLYGEGFRNRLSQLRELKRALIDFENDIVYTYTPLPESIESIALKAKSPIKELFNEISFKLKNNEVENVYMAFKESINEHKKEMNLRNKDFEILLDLSKSLGETNVEGQIKIFNLAKEKLDIELEIAEDECNKNTKVYRYLGVAVGAMIAIFLV
>NZ_CP023410.1|WP_003451671.1|931737_931935_+|stage-III-sporulation-protein-AC
MSDLSLIFQIAGVGIVLVILDKVLDQSGKKEYATLANIVGVVIILTMMIQLISRLFSSVKSMFLF
>NZ_CP023410.1|WP_003451406.1|932022_932409_+|stage-III-sporulation-protein-AD
MDVVIQVISFVLISLFLYLVLKDNKSTFAVFLLLGAGIVIFLFVMPYVNEIIAFMQDIARESGMDSSYIAIVMKIIAIAYLSTFCSYICNDAGVTVLGKKVEFTGKIMILLLAIPIMANILNSILSIM
>NZ_CP023410.1|WP_003458684.1|932419_933592_+|stage-III-sporulation-protein-AE
MKKLINIILLSLIFVFCFNLKVLANDNLESSKEKIDNDSRIERFYDYINNLETEEDILGNMSAKEYIMNYLESGEDPITLKKIGASILSYIFRELNIVLKFIASILVIALLSALLKNLQDAFNIEEGVTQIAFFACYALLIMLLTKSFFISLNLGKEVLTSIIDFMNVIVPVIVMLIATSGGVTSAVTIDPIVLGAVSITPRIYTYFLFPLILAYFTLQFVNNLSSEFKIDRMCKFIKQVVMISQGFILTIFVGILTLRGMTADTLDAVAVKTVKFAVDNFVPIVGKAFSDAITTVAGYSLAMKSVITSLGVIVIVVIVIYPIIKIGLMAICFKLTSAVIEPVVDSKISSSVETVGEALFMIMSCIISVSIMFFIMASMMATAGNFIVGG
>NZ_CP023410.1|WP_003458682.1|933599_934157_+|stage-III-sporulation-protein-AF
MELLKNWISTLCVVIVIISIAHIILPNSSIKKHVKFAFSLIILSVMLSPIIGLLTMNKDIDETVFQEKISDITRSDEEKKSLYDEEAILKSVEKNLEKSLKDEFYENEFEVNLIGKIDFDEVKFNIEKAEITVLDEKKVKKVDKVVVGKEKVNKEEKKDSFLEKIEKFVEKELEISHENIIVSYA
>NZ_CP023410.1|WP_003451336.1|934171_934777_+|stage-III-sporulation-protein-AG
MHELKEKIANLFKQKNITNLIILLLLVIMFYLVVSYFTGVNNITKSEKTNLEKVSKEDMNSNSQKDSEVLSYQEKQEKDLERILGKINGVGSVDVVINFQSSEVKVPAVDNSSQKSTTEETDSEGGTRVNSQETDGDKIVMSNSSNGSEPVILKTEKPEVLGVMVVAEGAEDSKIKYEITKAISSLYNISVDKVNVLAMKK
>NZ_CP023410.1|WP_003451536.1|934802_935300_+|stage-III-sporulation-protein-AH
MNRKQAGIILTLLALIVCTGVLATRVNNQIKESMGEVPTAFGENDDNATETSSNYFYESRNLREQKDSKTIDNLKAIVEDKNTSAEQKEEAEKELTEKTMARDYETRIELSIKSKGYEDVICFIDGDNAKVVVKTNEELTQEKMVEIQDIVMNVSKVYDVDIEKK
>NZ_CP023410.1|WP_003451410.1|935384_935774_+|Asp23/Gls24-family-envelope-stress-response-protein
MNEMNRDEANLGIVNISDEVIGVVAGIAASEIDGILEINHNNSTGIGHKFSKKSLGKGIKVNVENGEAVIEIGVTVQYGIKIPDVVSQVQENVRRTVEAITGLKVALVNIYVQNIIILKEEDKNEILKK
>NZ_CP023410.1|WP_003451187.1|935892_936300_+|transcription-antitermination-factor-NusB
MNRVKSREYLLQLAYQMEITSETALETFNSFMENEDISKDDLDLAYIKSGLLGIEENKEKLDSLIESQLVKWKLNRISKVNLSILRISTYEILFAEDVPGKVSINEAIELCKKYSDNKSVSFINGVLDKVYKNMQ

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Crispr_ID: NZ_CP023410_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023410_2

2128521-2130759

Unclear

I-A

Consensus_repeat	Method
ATTTACATTCCTCATAGTTAATATAAAAC	CRISPRCasFinder
ATTTACATTCCTCATAGTTAATATAAAAC	CRT
ATTTACATTCCTCATAGTTAATATAAAAC	PILER-CR

34 spacers

cas5,cas7,cas8b2,cas6,WYL

The CRISPR arrays of NZ_CP023410_2

>merge|NZ_CP023410|2|2128521-2130759|CRISPRCasFinder,CRT,PILER-CR
TTTTACACCCATCATAATTAATATAAAACGTAATCAATATATTATTTTAAGAGTTTTATCAGATGAATTTACATTTCTCATAGTTAAGATAAAATCGCTTAAATGGGAAGGCAAGGGTTAGAGCAAAAAATATTTACATTCCTCATAGTTAATATAAAACTGTTTCTTTAATATCTTATTAACTTTACCAAAACTAATTTACATTCCTCATAGTTAATATAAAACTTGAGATATATCCCTTAATTCTTGTTGATAACTTTTATTTACATTCCTCATAGTTAATATAAAACTTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAAATTTACATTCCTCATAGTTAATATAAAACCATGGAAAAGAAAAGATATAAAGAAAAGTAAAACTCCATTTACATTCCTCATAGTTAATATAAAACGAATTGTTGGGTGTCATAGTACATGTAGAGATTACAATTTACATTCCTCATAGTTAATATAAAACACGTTAGTTATTAGGAGGTATTTCAATGAAATTAGTATTTACATTCCTCATAGTTAATATAAAACCAAAGGAGCATTTAGTAGAGATTGGACACAAACATTATTTACATTCCTCATAGTTAATATAAAACGTTAAAATCTTTAAGTGTTAAATGTACACCAATGTTATTTACATTCCTCATAGTTAATATAAAACAGGCTTTCCAAATCATGAATGAAGATGATTTTAACAATTTACATTCCTCATAGTTAATATAAAACAAAATGGAAAAGTATTATTGTTCTTTTGGTTTCGTATTTACATTCCTCATAGTTAATATAAAACTAATAAAGTTTATAACATAGATATTCGTTCAGACAAATTTACATTCCTCATAGTTAATATAAAACCTTTCTCATTCTAATTCATCTCCTATACTATTAAAAATTTACATTCCTCATAGTTAATATAAAACTAATGCTACAAGTTCATCAGGTTCATCACCTATAAGATTTACATTCCTCATAGTTAATATAAAACCGAAGAACTTTTAAGATTAAGAGAAAAATATGGTAATATTTACATTCCTCATAGTTAATATAAAACGCAAAGGAGAAACAAAAGTATCTGCCTTTACTCTTTATTTACATTCCTCATAGTTAATATAAAACACAGTTTAAGTTATCATCTAATCTATTATCATTACTATTTACATTCCTCATAGTTAATATAAAACATAGTTCCAAACTCTCTAAAATATCCTACTTTAACAATTTACATTCCTCATAGTTAATATAAAACAGGAGTTATTAAAGCACCTATCAATGCAGCTATAAGATTTACATTCCTCATAGTTAATATAAAACGGAATTGTCTTTTAAAGATTGTGATTTAGGAGATTTACATTCCTCATAGTTAATATAAAACTTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAAATTTACATTCCTCATAGTTAATATAAAACTAATTTAGATATTGGAGATTATCCAGTTTTAGTACAATTTACATTCCTCATAGTTAATATAAAACCCATTACAGGATATAAAATGTGGAAAGAAGAAGGGAATTTACATTCCTCATAGTTAATATAAAACTTCTATCGTATAAGGATTATATTTAACAAATTTATAATTTACATTCCTCATAGTTAATATAAAACTTTTGAAAGTATATTTAAACAATTATTAAATATTTAATTTACATTCCTCATAGTTAATATAAAACTACTTGTACCAATTATAGCATTTTCAAAGCTAACATATTTACATTCCTCATAGTTAATATAAAACTACATTCTTCTCTTAATGCATTGTAAAGTTCTTCTTATTTACATTCCTCATAGTTAATATAAAACCTAGCTTCAATTCCATCTTTACTCCAAATATCAACTATTTACATTCCTCATAGTTAATATAAAACCCATAGCTTCCCTCTTTATTTTTAAGATTATAAATAAATTTACATTCCTCATAGTTAATATAAAACTATACTTAGTATTTCTTAGTATTACTTTACAATAATATTTACATTCCTCATAGTTAATATAAAACTAATTTAGATATTGGAGATTATCCAGTTTTAGTACAATTTACATTCCTCATAGTTAATATAAAACGAGATTCAGAAAGCGTTCTAGCTGCATTATTTTCCTTATTTACATTCCTCATAGTTAATATAAAACAAAAAGAGTTAGAGATTGACAAAGATACAATTGAAAATTTACATTCCTCATAGTTAATATAAAAC

>NZ_CP023410|2|2|2128521-2130759|CRISPRCasFinder
TTTTACACCCATCATAATTAATATAAAAC	GTAATCAATATATTATTTTAAGAGTTTTATCAGATGA
ATTTACATTTCTCATAGTTAAGATAAAAT	CGCTTAAATGGGAAGGCAAGGGTTAGAGCAAAAAAT
ATTTACATTCCTCATAGTTAATATAAAAC	TGTTTCTTTAATATCTTATTAACTTTACCAAAACTA
ATTTACATTCCTCATAGTTAATATAAAAC	TTGAGATATATCCCTTAATTCTTGTTGATAACTTTT
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAA
ATTTACATTCCTCATAGTTAATATAAAAC	CATGGAAAAGAAAAGATATAAAGAAAAGTAAAACTCC
ATTTACATTCCTCATAGTTAATATAAAAC	GAATTGTTGGGTGTCATAGTACATGTAGAGATTACA
ATTTACATTCCTCATAGTTAATATAAAAC	ACGTTAGTTATTAGGAGGTATTTCAATGAAATTAGT
ATTTACATTCCTCATAGTTAATATAAAAC	CAAAGGAGCATTTAGTAGAGATTGGACACAAACATT
ATTTACATTCCTCATAGTTAATATAAAAC	GTTAAAATCTTTAAGTGTTAAATGTACACCAATGTT
ATTTACATTCCTCATAGTTAATATAAAAC	AGGCTTTCCAAATCATGAATGAAGATGATTTTAACA
ATTTACATTCCTCATAGTTAATATAAAAC	AAAATGGAAAAGTATTATTGTTCTTTTGGTTTCGT
ATTTACATTCCTCATAGTTAATATAAAAC	TAATAAAGTTTATAACATAGATATTCGTTCAGACAA
ATTTACATTCCTCATAGTTAATATAAAAC	CTTTCTCATTCTAATTCATCTCCTATACTATTAAAA
ATTTACATTCCTCATAGTTAATATAAAAC	TAATGCTACAAGTTCATCAGGTTCATCACCTATAAG
ATTTACATTCCTCATAGTTAATATAAAAC	CGAAGAACTTTTAAGATTAAGAGAAAAATATGGTAAT
ATTTACATTCCTCATAGTTAATATAAAAC	GCAAAGGAGAAACAAAAGTATCTGCCTTTACTCTTT
ATTTACATTCCTCATAGTTAATATAAAAC	ACAGTTTAAGTTATCATCTAATCTATTATCATTACT
ATTTACATTCCTCATAGTTAATATAAAAC	ATAGTTCCAAACTCTCTAAAATATCCTACTTTAACA
ATTTACATTCCTCATAGTTAATATAAAAC	AGGAGTTATTAAAGCACCTATCAATGCAGCTATAAG
ATTTACATTCCTCATAGTTAATATAAAAC	GGAATTGTCTTTTAAAGATTGTGATTTAGGAG
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAA
ATTTACATTCCTCATAGTTAATATAAAAC	TAATTTAGATATTGGAGATTATCCAGTTTTAGTACA
ATTTACATTCCTCATAGTTAATATAAAAC	CCATTACAGGATATAAAATGTGGAAAGAAGAAGGGA
ATTTACATTCCTCATAGTTAATATAAAAC	TTCTATCGTATAAGGATTATATTTAACAAATTTATA
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTGAAAGTATATTTAAACAATTATTAAATATTTA
ATTTACATTCCTCATAGTTAATATAAAAC	TACTTGTACCAATTATAGCATTTTCAAAGCTAACAT
ATTTACATTCCTCATAGTTAATATAAAAC	TACATTCTTCTCTTAATGCATTGTAAAGTTCTTCTT
ATTTACATTCCTCATAGTTAATATAAAAC	CTAGCTTCAATTCCATCTTTACTCCAAATATCAACT
ATTTACATTCCTCATAGTTAATATAAAAC	CCATAGCTTCCCTCTTTATTTTTAAGATTATAAATAA
ATTTACATTCCTCATAGTTAATATAAAAC	TATACTTAGTATTTCTTAGTATTACTTTACAATAAT
ATTTACATTCCTCATAGTTAATATAAAAC	TAATTTAGATATTGGAGATTATCCAGTTTTAGTACA
ATTTACATTCCTCATAGTTAATATAAAAC	GAGATTCAGAAAGCGTTCTAGCTGCATTATTTTCCTT
ATTTACATTCCTCATAGTTAATATAAAAC	AAAAAGAGTTAGAGATTGACAAAGATACAATTGAAA
ATTTACATTCCTCATAGTTAATATAAAAC

>NZ_CP023410|2|1|2128521-2130759|CRT
TTTTACACCCATCATAATTAATATAAAAC	GTAATCAATATATTATTTTAAGAGTTTTATCAGATGA
ATTTACATTTCTCATAGTTAAGATAAAAT	CGCTTAAATGGGAAGGCAAGGGTTAGAGCAAAAAAT
ATTTACATTCCTCATAGTTAATATAAAAC	TGTTTCTTTAATATCTTATTAACTTTACCAAAACTA
ATTTACATTCCTCATAGTTAATATAAAAC	TTGAGATATATCCCTTAATTCTTGTTGATAACTTTT
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAA
ATTTACATTCCTCATAGTTAATATAAAAC	CATGGAAAAGAAAAGATATAAAGAAAAGTAAAACTCC
ATTTACATTCCTCATAGTTAATATAAAAC	GAATTGTTGGGTGTCATAGTACATGTAGAGATTACA
ATTTACATTCCTCATAGTTAATATAAAAC	ACGTTAGTTATTAGGAGGTATTTCAATGAAATTAGT
ATTTACATTCCTCATAGTTAATATAAAAC	CAAAGGAGCATTTAGTAGAGATTGGACACAAACATT
ATTTACATTCCTCATAGTTAATATAAAAC	GTTAAAATCTTTAAGTGTTAAATGTACACCAATGTT
ATTTACATTCCTCATAGTTAATATAAAAC	AGGCTTTCCAAATCATGAATGAAGATGATTTTAACA
ATTTACATTCCTCATAGTTAATATAAAAC	AAAATGGAAAAGTATTATTGTTCTTTTGGTTTCGT
ATTTACATTCCTCATAGTTAATATAAAAC	TAATAAAGTTTATAACATAGATATTCGTTCAGACAA
ATTTACATTCCTCATAGTTAATATAAAAC	CTTTCTCATTCTAATTCATCTCCTATACTATTAAAA
ATTTACATTCCTCATAGTTAATATAAAAC	TAATGCTACAAGTTCATCAGGTTCATCACCTATAAG
ATTTACATTCCTCATAGTTAATATAAAAC	CGAAGAACTTTTAAGATTAAGAGAAAAATATGGTAAT
ATTTACATTCCTCATAGTTAATATAAAAC	GCAAAGGAGAAACAAAAGTATCTGCCTTTACTCTTT
ATTTACATTCCTCATAGTTAATATAAAAC	ACAGTTTAAGTTATCATCTAATCTATTATCATTACT
ATTTACATTCCTCATAGTTAATATAAAAC	ATAGTTCCAAACTCTCTAAAATATCCTACTTTAACA
ATTTACATTCCTCATAGTTAATATAAAAC	AGGAGTTATTAAAGCACCTATCAATGCAGCTATAAG
ATTTACATTCCTCATAGTTAATATAAAAC	GGAATTGTCTTTTAAAGATTGTGATTTAGGAG
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAA
ATTTACATTCCTCATAGTTAATATAAAAC	TAATTTAGATATTGGAGATTATCCAGTTTTAGTACA
ATTTACATTCCTCATAGTTAATATAAAAC	CCATTACAGGATATAAAATGTGGAAAGAAGAAGGGA
ATTTACATTCCTCATAGTTAATATAAAAC	TTCTATCGTATAAGGATTATATTTAACAAATTTATA
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTGAAAGTATATTTAAACAATTATTAAATATTTA
ATTTACATTCCTCATAGTTAATATAAAAC	TACTTGTACCAATTATAGCATTTTCAAAGCTAACAT
ATTTACATTCCTCATAGTTAATATAAAAC	TACATTCTTCTCTTAATGCATTGTAAAGTTCTTCTT
ATTTACATTCCTCATAGTTAATATAAAAC	CTAGCTTCAATTCCATCTTTACTCCAAATATCAACT
ATTTACATTCCTCATAGTTAATATAAAAC	CCATAGCTTCCCTCTTTATTTTTAAGATTATAAATAA
ATTTACATTCCTCATAGTTAATATAAAAC	TATACTTAGTATTTCTTAGTATTACTTTACAATAAT
ATTTACATTCCTCATAGTTAATATAAAAC	TAATTTAGATATTGGAGATTATCCAGTTTTAGTACA
ATTTACATTCCTCATAGTTAATATAAAAC	GAGATTCAGAAAGCGTTCTAGCTGCATTATTTTCCTT
ATTTACATTCCTCATAGTTAATATAAAAC	AAAAAGAGTTAGAGATTGACAAAGATACAATTGAAA
ATTTACATTCCTCATAGTTAATATAAAAC

>NZ_CP023410|2|1|2128652-2130759|PILER-CR
ATTTACATTCCTCATAGTTAATATAAAAC	TGTTTCTTTAATATCTTATTAACTTTACCAAAACTA
ATTTACATTCCTCATAGTTAATATAAAAC	TTGAGATATATCCCTTAATTCTTGTTGATAACTTTT
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAA
ATTTACATTCCTCATAGTTAATATAAAAC	CATGGAAAAGAAAAGATATAAAGAAAAGTAAAACTCC
ATTTACATTCCTCATAGTTAATATAAAAC	GAATTGTTGGGTGTCATAGTACATGTAGAGATTACA
ATTTACATTCCTCATAGTTAATATAAAAC	ACGTTAGTTATTAGGAGGTATTTCAATGAAATTAGT
ATTTACATTCCTCATAGTTAATATAAAAC	CAAAGGAGCATTTAGTAGAGATTGGACACAAACATT
ATTTACATTCCTCATAGTTAATATAAAAC	GTTAAAATCTTTAAGTGTTAAATGTACACCAATGTT
ATTTACATTCCTCATAGTTAATATAAAAC	AGGCTTTCCAAATCATGAATGAAGATGATTTTAACA
ATTTACATTCCTCATAGTTAATATAAAAC	AAAATGGAAAAGTATTATTGTTCTTTTGGTTTCGT
ATTTACATTCCTCATAGTTAATATAAAAC	TAATAAAGTTTATAACATAGATATTCGTTCAGACAA
ATTTACATTCCTCATAGTTAATATAAAAC	CTTTCTCATTCTAATTCATCTCCTATACTATTAAAA
ATTTACATTCCTCATAGTTAATATAAAAC	TAATGCTACAAGTTCATCAGGTTCATCACCTATAAG
ATTTACATTCCTCATAGTTAATATAAAAC	CGAAGAACTTTTAAGATTAAGAGAAAAATATGGTAAT
ATTTACATTCCTCATAGTTAATATAAAAC	GCAAAGGAGAAACAAAAGTATCTGCCTTTACTCTTT
ATTTACATTCCTCATAGTTAATATAAAAC	ACAGTTTAAGTTATCATCTAATCTATTATCATTACT
ATTTACATTCCTCATAGTTAATATAAAAC	ATAGTTCCAAACTCTCTAAAATATCCTACTTTAACA
ATTTACATTCCTCATAGTTAATATAAAAC	AGGAGTTATTAAAGCACCTATCAATGCAGCTATAAG
ATTTACATTCCTCATAGTTAATATAAAAC	GGAATTGTCTTTTAAAGATTGTGATTTAGGAG
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTACTTGTAAGTGCTTCAAAGCTAGTAATACCAA
ATTTACATTCCTCATAGTTAATATAAAAC	TAATTTAGATATTGGAGATTATCCAGTTTTAGTACA
ATTTACATTCCTCATAGTTAATATAAAAC	CCATTACAGGATATAAAATGTGGAAAGAAGAAGGGA
ATTTACATTCCTCATAGTTAATATAAAAC	TTCTATCGTATAAGGATTATATTTAACAAATTTATA
ATTTACATTCCTCATAGTTAATATAAAAC	TTTTGAAAGTATATTTAAACAATTATTAAATATTTA
ATTTACATTCCTCATAGTTAATATAAAAC	TACTTGTACCAATTATAGCATTTTCAAAGCTAACAT
ATTTACATTCCTCATAGTTAATATAAAAC	TACATTCTTCTCTTAATGCATTGTAAAGTTCTTCTT
ATTTACATTCCTCATAGTTAATATAAAAC	CTAGCTTCAATTCCATCTTTACTCCAAATATCAACT
ATTTACATTCCTCATAGTTAATATAAAAC	CCATAGCTTCCCTCTTTATTTTTAAGATTATAAATAA
ATTTACATTCCTCATAGTTAATATAAAAC	TATACTTAGTATTTCTTAGTATTACTTTACAATAAT
ATTTACATTCCTCATAGTTAATATAAAAC	TAATTTAGATATTGGAGATTATCCAGTTTTAGTACA
ATTTACATTCCTCATAGTTAATATAAAAC	GAGATTCAGAAAGCGTTCTAGCTGCATTATTTTCCTT
ATTTACATTCCTCATAGTTAATATAAAAC	AAAAAGAGTTAGAGATTGACAAAGATACAATTGAAA
ATTTACATTCCTCATAGTTAATATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023410.1\|WP_004456253.1\|2121556_2122705_-\|lactaldehyde-reductase	unknown	unknown	gnl\|CDD\|182595
NZ_CP023410.1\|WP_078233520.1\|2140900_2141353_-\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|225876
NZ_CP023410.1\|WP_003461999.1\|2118699_2120493_-\|L-fucose-isomerase	unknown	unknown	gnl\|CDD\|182885
NZ_CP023410.1\|WP_003453965.1\|2123465_2123978_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP023410.1\|WP_078233522.1\|2138390_2139080_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_049040166.1\|2126709_2127414_+\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
NZ_CP023410.1\|WP_078233530.1\|2124275_2124755_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240044
NZ_CP023410.1\|WP_003477471.1\|2139080_2139470_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_078233521.1\|2139501_2140458_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_078233523.1\|2137392_2138343_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP023410.1\|WP_078233525.1\|2135120_2136458_-\|type-I-CRISPR-associated-protein-Cas8a1/Csx8	cas8b2	cd09744_cas8b2_CAS-I-B	gnl\|CDD\|187875
NZ_CP023410.1\|WP_078233524.1\|2136481_2137204_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NZ_CP023410.1\|WP_078233531.1\|2120643_2121501_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP023410.1\|WP_004456258.1\|2125778_2126336_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_003459132.1\|2122875_2123478_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_078233527.1\|2133135_2134230_-\|CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|274218
NZ_CP023410.1\|WP_078233519.1\|2141793_2142300_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_011590538.1\|2124876_2125227_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_078233526.1\|2134233_2135121_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NZ_CP023410.1\|WP_078233529.1\|2127435_2128131_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223803

Protein	Function_ID	Function_description	E-value
NZ_CP023410.1\|WP_004456253.1\|2121556_2122705_-\|lactaldehyde-reductase	gnl\|CDD\|182595	PRK10624, PRK10624, L-1,2-propanediol oxidoreductase; Provisional.	0
NZ_CP023410.1\|WP_003461999.1\|2118699_2120493_-\|L-fucose-isomerase	gnl\|CDD\|182885	PRK10991, fucI, L-fucose isomerase; Provisional.	0
NZ_CP023410.1\|WP_003453965.1\|2123465_2123978_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.7253e-10
NZ_CP023410.1\|WP_049040166.1\|2126709_2127414_+\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	1.27701e-100
NZ_CP023410.1\|WP_078233530.1\|2124275_2124755_+\|NUDIX-domain-containing-protein	gnl\|CDD\|240044	cd04688, Nudix_Hydrolase_29, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	2.32296e-34
NZ_CP023410.1\|WP_078233520.1\|2140900_2141353_-\|DUF1232-domain-containing-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	2.17938e-11
NZ_CP023410.1\|WP_078233523.1\|2137392_2138343_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.14501e-32
NZ_CP023410.1\|WP_078233525.1\|2135120_2136458_-\|type-I-CRISPR-associated-protein-Cas8a1/Csx8	gnl\|CDD\|187875	cd09744, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as Csx8 family.	0
NZ_CP023410.1\|WP_078233524.1\|2136481_2137204_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	2.20984e-24
NZ_CP023410.1\|WP_078233531.1\|2120643_2121501_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.51526e-32
NZ_CP023410.1\|WP_078233527.1\|2133135_2134230_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|274218	TIGR02593, CRISPR-associated_protein_Cas5, CRISPR-associated protein Cas5, N-terminal domain. This model represents a shared N-terminal domain, about 43 amino acids in length, common to a number of related protein families each of which is associated with a distinct subtype of CRISPR/cas system, where CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat and Cas is an abbreviation for CRISPR-associated. Members of this family are widely distributed enough that we designated the family Cas5. Homology appears remote, or absent, between the more C-terminal regions different subfamilies of these proteins, which typically are 210 to 265 amino acids in total length. Cas5 proteins of six different CRISPR/cas subtypes so far defined are described by respective full-length models TIGR01868, TIGR01876, TIGR01895, TIGR01874, TIGR02586, and TIGR02592. The best characterized protein in this family is DevS or Myxococcus xanthus, a Cas protein that appears to participate in a species-specific developmental pathway.	3.23429e-08
NZ_CP023410.1\|WP_078233526.1\|2134233_2135121_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	1.27879e-48
NZ_CP023410.1\|WP_078233529.1\|2127435_2128131_+\|radical-SAM-protein	gnl\|CDD\|223803	COG0731, COG0731, Fe-S oxidoreductases [Energy production and conversion].	9.61952e-18

>NZ_CP023410.1|WP_078233529.1|2127435_2128131_+|radical-SAM-protein
MDNFTYKEVYIEDGKRVLEINVLPEKYCNFDCIFCPIGRSKNKIDNQKSFHNVDESLIELENMINDTKPDLIFINSKGEALINDKIEDIIDFIKSKRVPVRLLSNGYILGKDEYIKVANKCDEVIGEIKVITEEDFKKVQRPIEGYTLHEYISNMASFNKQYNGKFIFEITIVKGYNDDPESVNKLKEVIKAICPNEVIVARIDDDIFKKKLGISDERFEEISRELLAVNC
>NZ_CP023410.1|WP_049040166.1|2126709_2127414_+|B3/4-domain-containing-protein
MKKFIIEDDFWELFPNAKIGIITCNGIDNTIKDENQYKDMISQGEKEALNHLPNEEFSSNEVIKVWRDAFKKFKTKKGARSSIEALLKRVSTGKGLGTINPLVDIYNSISLKYAMPCGGEDMDKFIGDIRLTKATGDESFITLGSDKSEPPYEGEIVYKDDEGAICRCWNWRESVRTMLTEDTKNAFLCIELVDEKREKDFENALKELSQLVEENLGGKSEISILHINNKEAII
>NZ_CP023410.1|WP_004456258.1|2125778_2126336_-|hypothetical-protein
MKKRIERLIIFCMLITITIPNIAYAKTNMRYEQEKTNIVEPYGPKIEDLKSKDVIINNLQEIKRIRGNLTAVNISESSTPNELKDVYNRLDFYIQEFIEIKKNLDNNIKTYTNSFSDKFFSEQVLFIAESYIVSLRQQQNLIIALQEKKVDAKKLVYSSYLIPIYHYITLGDQMTAYVDTYFVVI
>NZ_CP023410.1|WP_011590538.1|2124876_2125227_-|hypothetical-protein
MKKLAFIIKNILKFWYWQDIEKSNIFIRLMNLGMALFLSFCLLVWMYGENWNIILRLFISIYGVLCFMSFWPVSYLFDEKDKVKGSTFYIFQNISVFFSIIILVVYILKNYDRVKS
>NZ_CP023410.1|WP_078233530.1|2124275_2124755_+|NUDIX-domain-containing-protein
MEYDCGFVKESNWFRYRAGAIIIEDESVLFASNEREDYYYSIGGGVHMGESAEEAVKREVFEETGVKYEVDRLVFIHENFFKGDGSLEGKNCHEICFYFLMKPRGTRNLNSNSYTSEVKEIMYWIPIEELSNYRAYPTFFREKLTNLKNEIEHIVTYEY
>NZ_CP023410.1|WP_003453965.1|2123465_2123978_-|flavodoxin-family-protein
MRLLLSDKELNINFLESDENKYIDLSKLRISNCIGCFGCWTKTPGKCVIRDDAVKVYPIIAKSDKVIYVSKVKYGSYDTVMKTMLERAIPIQQAFIRLLNGEAHHVQRDVAMKDAIIIAYGNIEDEEKEIFKRLVERNSHNMNFKSFNVIFVDEENLEEVVAKEVRKWEK
>NZ_CP023410.1|WP_003459132.1|2122875_2123478_-|hypothetical-protein
MGKVIIINGSPRAPRSNSKKYGEIFRSYYKGKADTFNITKNNHKEICSKIGEYKDMLLVFPLYADGLPVTMLNFLKVLEENPPKNKPKVNVIVNCGFIEPEQNNVCIDMVKLFCKQNTYEFNSVLSIGGGEAILGTPFKIFVKWKIKKLAKSIYNNTPENLRVTMPISKNMYLKASTNYWINYGKRNGITKSQMETMKIE
>NZ_CP023410.1|WP_004456253.1|2121556_2122705_-|lactaldehyde-reductase
MVNRIVLNETSYHGAGAIKEIVTEVKGRGFKKAFLCSDPDLVKFGVTGKVTSILDEANLSYELYTNIKANPTIENVKSGVEAYKKSGADYIIAVGGGSSMDTAKAIGIIINNKEFEDVVSLEGVAPTKNKSVPIIAVPTTAGTAAEVTINYVITDVEKNRKFVCVDTHDIPVVAIIDPEMMQSMPKGLTAATGMDALTHAIEGYITGAAWEMTDMFHLKAIELISKHLRSAVENTPEGREGMALGQYIAGMGFSNVGLGIVHSMAHSLGAVYDTPHGVANAIILPTVMEYNAEETGDKYKYIAAAMGVENTENMTVEEYRKAAVDEVKKLSEDVGIPANLKDIVKKEDIRFLAESAYNDACRPGNPKETSVEDIIALYESLM
>NZ_CP023410.1|WP_078233531.1|2120643_2121501_+|AraC-family-transcriptional-regulator
MKYFDYKENKQHGTFDFPIEFYHVTPNHSRYNMPYHWHTECEIIRILEGEFILFIDKEKILAKKNDIIFVHSGIFHGGLPNDCIYECIVFDMKLLLKDNNACTKQIYDIVNHNKVIAHKLPSNVQALNNCCTSLFEAMRVKSTGYEFIAQGDLYYLIGTILENQLYVKNNKYTKKTKERFLQLKNVITLIENEYQNPLTLEDLSKASGMSPKYFCRFFHEMINKTPIEYLNYYRIEISCEKLLATELSITEIALNCGFNDVSYFIKTFKKHKGVTPKQYLKSLKA
>NZ_CP023410.1|WP_003461999.1|2118699_2120493_-|L-fucose-isomerase
MAKSRLVGKYPVIGIRPTIDGRRGIIDVRGSLEEQTMNMAKSAAKLLEENLKYSNGEKVKVIIADTTIGRVPEAAACADKFRKEGVDITLTVTPCWCYGAETMDMDPMTIKGVWGFNGTERPGAVYLASVLATHAQKGLPAFGIYGHDVQNADDTEIPEDVKEKILRFGRSAIAAASMRGKSYLQIGSICMGIGGSIIDPNFIEEYLGMRVESVDEVEIIRRMTEEIYDKDEFERALKWTKEKCKEGFDKNPENVQKTREEKDKDWEFVVKMMCIIKDLMNGNENLPDGFEEEKLGHNAIAAGFQGQRQWTDFYPNCDFPEALLNTSFDWNGAREPYILATENDVLNGLGMLFGKLLTNKAQIFADVRTYWSPDAVKKATGYELEGVAKESDGFIHLINSGAACLDACGQAKDENGNGTMKAWYDVTEEDQEAILAATTWNAADNGYFRGGGYSSRFLTEAEMPVTMIRLNLVKGLGPVVQLVEGYSVKLPDEVSDKLWKRTDYTWPCTWFAPRLTGKGAFKSAYDVMNNWGANHGAISHGHIGADIITLCSILRIPVSMHNVPEEKIFRPAAWNAFGMDKEGQDYRACKAYGPMYK
>NZ_CP023410.1|WP_078233527.1|2133135_2134230_-|CRISPR-associated-protein-Cas5
MKALRIILTQNSANYRREETTVNKMTYPLPPFSTVIGAIHNACNYKEYKPMDISIQGTYESMGLEPYTDYCFLNTVMDDRGILVKLKNGKYLSNSFDKVAKALKSQGNSFREGKTIQVYNEKLLEEYRNLKGLKDKIDEFSRGKLKEVLNLIKLRKKTLSSKKKELKDNKEKLELIKKREIQIKDLEKRLKSEFDDYKEKNYNEPYSKFASLTTSLKYYETLYNVKLIIHIRCEDENTLLDIKENIYNLKSIGRSEDFVDIKEVKIVDLVEDPDELEDEIVNSNYAYVNYDLVKNDIIMPINLSDNRVCNGTKYLLNKNYKIEDKKRKFEKKKVLYISKYVVDEAYENLYFDVEDKEKYIVNFI
>NZ_CP023410.1|WP_078233526.1|2134233_2135121_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKGKSVTLTVIANMTSNYGEGLGNISSVQKVFKNGKTYAARSKESLKNAIMVQSGLYDDLETSLDKKVNQKVVSKDLNVTNCRALEGGYMNTSDNTYVRKSSFYLTDAVSCDEFINEYRFHNNLYLATNYAKHNNINLQGNAQKAGLMPYQYEFDKSLKIYSLTIDLDMIGRDENFDSEEASAEEKAYRVNAILDAVKNLSLIVKGNLDNAEPIFVVGGIINRKTHYFESLVKVKNDKLEITEELKDRINNGCYVGFLEGGNFENEVQIKEELKPLTVSKFFSNLEEEVRKYYGV
>NZ_CP023410.1|WP_078233525.1|2135120_2136458_-|type-I-CRISPR-associated-protein-Cas8a1/Csx8
MEEKVFDCTVETGDWRYSAAIVGLIKYFDFLYQNGVADKSELYEFEDDYLRYDSNYISEENYLLFVEKYFKDAMHHKVVENILLKDELSEDEIVLINDKLKANQAMKSIFGKIKYTGENKEEILDLIEKNRLKLIKETYRRGKSLYSNFANENLLFSDNNKVCRLVNYCADMGKKGKSLGYYWDNNTFEFKNEKIFDFIPFAFSKSYDAFFINNNVSIKELKKSNSFIENSDNTRTTLFGNMKESAEYIGFDVEVILKSRDKNYYETVYVREKAINIFKQSDDFDYKGIKFWYRDDEKNPKYMEPEIVNRILNGIRMDSIIELLFKSKNNHSYNIKTLIAINNLIYEGGSEMTKKMKSAYASAKRVSEKLEENKLNSYKQKLISAVTFKNKDRFCEILLQLSSFSGVVFDFAYDLFDDFENNKNLAYTFINALNKEGNKENGGDK
>NZ_CP023410.1|WP_078233524.1|2136481_2137204_-|CRISPR-associated-endoribonuclease-Cas6
MKILVAGKMKNKKISLSYRMFILSMIKKIISDFDQSYFEEMFFYEGKKTKKTKPFTFSVFFKDYKINKDFVEVEGEVKIVISTPDIKLNMVLFNGFMKMKEYGDFEKTSVRIEKERKVEENEAIFKTLSPIFIKDANNKALEIEDENYNKELNYFANLSIKSFRGYGLKEELVFTPLNMKKVVIKEEISGFKEKTNKKYIYFNSYSGVFNLRGDKDDLNLLKELGIGVRRNIGFGSIDLI
>NZ_CP023410.1|WP_078233523.1|2137392_2138343_-|WYL-domain-containing-protein
MSTLGNTLRMLMMLRSGRKLKVKEIAEELEVSEKQVKRYKEALSEFFYIESKSGIDGGYILRDKYIPIKELLDEHEINLLKYSIDALEDFSLESNKDLKRAIDKINYSIEKGHNSNNEKTNSIIPYGRSLPINNKLQEMIDVIFEAIISNKEVFIEYSGNNGEVSKRTIQPYKIFTFKGEQYVIANCLSKNQVRYFKLIRIKGYHISNKIFKKTLDVDKLIENNKKNSIGIFGGKKYNLILEITPPMANTIKEKIWVYNQEVIELENGKILFKATMEGLPEIISWILSMREYVKIIEPLEIKEEVRLSVQKIINNL
>NZ_CP023410.1|WP_078233522.1|2138390_2139080_-|hypothetical-protein
MHSSKKLNSYIVANLIITGIILVISILMHRISIIFFLNLILIGALNIALLNRAKYSLDLLRKLRKLEDVDFPKFKDISMVLLGILFSIVTYTSLFLDSIGIIDISKILGEGGQANNTLISIILLIICLWAFITNLPGAIVTESTNKGRKFFDLSENNVALGNEALNRATGSFKNGIILGYYIFYFKNIQVAYRDKSGNIIVEGYNKSPFKITIAAKRSKKYFSKILDVD
>NZ_CP023410.1|WP_003477471.1|2139080_2139470_-|hypothetical-protein
MNNNKKFKFIVYLDNKELVKQFFYTNIAPFTYYTLPVCGIPAGKVIFEIENRKIYLKAKINDFEKGEHIETLSEIGFEDLDDFSINKTKNKDVYHITMAKKKHKVGLNCSNGLNDELAKEIVQYVRESA
>NZ_CP023410.1|WP_078233521.1|2139501_2140458_-|hypothetical-protein
MRKLVSLLLSIGILSGAFIGCGRNNQTEVSDNENSSNISSEEKNNKEEVKNDNNDKKESKDSENDIKDNKDKNEQRDKEDLNKENMKDEKDNTKKEERDSKLDESVIVNNGIITIPKNLKMAKIMLNYNGGNPLEVNEIKDYREVENNEMLYGVIIGDNPLKLGSINGQWEYNTLVTKFDTIKYPNFFEVQEKEMPELEFGITLKSKDKQMEFSLGSYINHMENDAKEEFENLIETFKKEGKVINKNQEGNTFSFTVEKDGFMEYHYGYISVKGDDVNTFIYKYPVKYKDVFNKIIEESKKSFVPTKQFPKLSNNTNK
>NZ_CP023410.1|WP_078233520.1|2140900_2141353_-|DUF1232-domain-containing-protein
MSEENKELIIEEVEIKGKKRKINLEKYAKFFSDKDFFEKLRKFAKKAGIKVVYTCLLLYYLLKKDTTPKWAKSIIIGALGYFIFSIDFLPDIAPIVGYTDDLGLLIPALGAVAFYIDEEVKEQAKKKLKDWFGEYEEDSLEDINEKISRG
>NZ_CP023410.1|WP_078233519.1|2141793_2142300_-|hypothetical-protein
MNKFEKTLLKHNIGYLDERDEYQQGVIYETLATANLYLSYLLIICMVISLIFDGINHSLTFGTFALAALQFGNSCYILNKLKKSGAYETEVYDDYTYNMEIKKLKKQCIISAIQWGIFMFFVMTYLWPWILGEPINVGLRQVIAWTIGGTLFGLLCYAISKSKIKKVV

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Crispr_ID: NZ_CP023410_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023410_3

2208713-2208914

Orphan

Consensus_repeat	Method
ACCTAAAAACAAATATTGTTTAAAA	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP023410_3

>merge|NZ_CP023410|3|2208713-2208914|CRISPRCasFinder
ACCTAAAATCAATATTCTATTAATAGTAACTACTAAAAAGCTGTTAGCACCTAAAAACAAATATTGTTTAAAAGTATCTAGTTTAGATTTTATTTAATATTTGCTCGTAAATAGACCTAAAAGCAAATATTGTTTAAAATCATCTATTGTAATGCCAAAAGAAAAGATGGTTTGTGCACCTAAAAAATAAAGCTTGTTTAAA

>NZ_CP023410|3|3|2208713-2208914|CRISPRCasFinder
ACCTAAAATCAATATTCTATTAATA	GTAACTACTAAAAAGCTGTTAGC
ACCTAAAAACAAATATTGTTTAAAA	GTATCTAGTTTAGATTTTATTTAATATTTGCTCGTAAATAG
ACCTAAAAGCAAATATTGTTTAAAA	TCATCTATTGTAATGCCAAAAGAAAAGATGGTTTGTGC
ACCTAAAAAATAAAGCTTGTTTAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023410.1\|WP_003454005.1\|2208939_2209416_-\|glutathione-peroxidase	unknown	unknown	gnl\|CDD\|238207
NZ_CP023410.1\|WP_078233484.1\|2204702_2205323_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP023410.1\|WP_003453976.1\|2214847_2215138_-\|ethanolamine-utilization-microcompartment-protein-EutM	unknown	unknown	gnl\|CDD\|132899
NZ_CP023410.1\|WP_003453880.1\|2213993_2214770_-\|ethanolamine-utilization-cobalamin-adenosyltransferase	unknown	unknown	gnl\|CDD\|227149
NZ_CP023410.1\|WP_078233485.1\|2203834_2204260_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341244
NZ_CP023410.1\|WP_003455851.1\|2212382_2213141_-\|ethanolamine-utilization-protein	unknown	unknown	gnl\|CDD\|274184
NZ_CP023410.1\|WP_078233487.1\|2201115_2202927_-\|ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|236212
NZ_CP023410.1\|WP_003459849.1\|2200277_2200496_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_003477263.1\|2211407_2211962_-\|BMC-domain-containing-protein	unknown	unknown	gnl\|CDD\|131578
NZ_CP023410.1\|WP_078233486.1\|2203166_2203655_-\|DUF2691-family-protein	unknown	unknown	gnl\|CDD\|371294
NZ_CP023410.1\|WP_078233483.1\|2205404_2207045_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|225110
NZ_CP023410.1\|WP_078233488.1\|2200660_2201119_-\|4Fe-4S-cluster-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379137
NZ_CP023410.1\|WP_060669957.1\|2210259_2211357_-\|ethanolamine-utilization-protein-EutH	unknown	unknown	gnl\|CDD\|237906
NZ_CP023410.1\|WP_003459816.1\|2207358_2207670_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023410.1\|WP_087327787.1\|2209783_2210263_-\|DUF861-domain-containing-protein	unknown	unknown	gnl\|CDD\|114941
NZ_CP023410.1\|WP_003477359.1\|2198777_2199563_+\|phosphorylase	unknown	unknown	gnl\|CDD\|350158
NZ_CP023410.1\|WP_025649037.1\|2215492_2216971_-\|acetaldehyde-dehydrogenase-(acetylating)	unknown	unknown	gnl\|CDD\|131570
NZ_CP023410.1\|WP_003459864.1\|2207961_2208507_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP023410.1\|WP_003455694.1\|2213348_2213984_-\|phosphate-propanoyltransferase	unknown	unknown	gnl\|CDD\|237899
NZ_CP023410.1\|WP_003474302.1\|2211963_2212236_-\|EutN/CcmL-family-microcompartment-protein	unknown	unknown	gnl\|CDD\|377017

Protein	Function_ID	Function_description	E-value
NZ_CP023410.1\|WP_087327787.1\|2209783_2210263_-\|DUF861-domain-containing-protein	gnl\|CDD\|114941	pfam06249, EutQ, Ethanolamine utilisation protein EutQ. The eut operon of Salmonella typhimurium encodes proteins involved in the cobalamin-dependent degradation of ethanolamine. The role of EutQ in this process is unclear.	2.00802e-93
NZ_CP023410.1\|WP_078233484.1\|2204702_2205323_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	8.77845e-52
NZ_CP023410.1\|WP_003453976.1\|2214847_2215138_-\|ethanolamine-utilization-microcompartment-protein-EutM	gnl\|CDD\|132899	cd07059, BMC_PduA, 1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain. PduA is encoded within the 1,2-propanediol utilization (pdu) operon along with other homologous carboxysome shell proteins PduB, B', J, K, T, and U. PduA is thought to be required for the formation of the outer shell of bacterial pdu polyhedral organelles which are involved in coenzyme B12-dependent degradation of 1,2-propanediol. Although it has been suggested that PduA might form hexamers and further assemble into the flat facets of the polyhedral outer shell of pdu organelles, like PduU does, at present no experimental evidence directly supports this view.	4.19683e-40
NZ_CP023410.1\|WP_003453880.1\|2213993_2214770_-\|ethanolamine-utilization-cobalamin-adenosyltransferase	gnl\|CDD\|227149	COG4812, EutT, Ethanolamine utilization cobalamin adenosyltransferase [Amino acid transport and metabolism].	1.25082e-69
NZ_CP023410.1\|WP_078233485.1\|2203834_2204260_-\|hypothetical-protein	gnl\|CDD\|341244	cd05920, 23DHB-AMP_lg, 2,3-dihydroxybenzoate-AMP ligase. 2,3-dihydroxybenzoate-AMP ligase activates 2,3-dihydroxybenzoate (DHB) by ligation of AMP from ATP with the release of pyrophosphate. However, it can also catalyze the ATP-PPi exchange for 2,3-DHB analogs, such as salicyclic acid (o-hydrobenzoate), as well as 2,4-DHB and 2,5-DHB, but with less efficiency. Proteins in this family are the stand-alone adenylation components of non-ribosomal peptide synthases (NRPSs) involved in the biosynthesis of siderophores, which are low molecular weight iron-chelating compounds synthesized by many bacteria to aid in the acquisition of this vital trace elements. In Escherichia coli, the 2,3-dihydroxybenzoate-AMP ligase is called EntE, the adenylation component of the enterobactin NRPS system.	0.00249782
NZ_CP023410.1\|WP_078233487.1\|2201115_2202927_-\|ribonucleoside-triphosphate-reductase	gnl\|CDD\|236212	PRK08270, PRK08270, ribonucleoside triphosphate reductase.	0
NZ_CP023410.1\|WP_003477263.1\|2211407_2211962_-\|BMC-domain-containing-protein	gnl\|CDD\|131578	TIGR02526, putative_ethanolamine_utilization_protein, PduT-like ethanolamine utilization protein. This gene shows up in ethanolamine utilization operons in which a proteinaceous coat organelle is also encoded. It is closely related to the PduT protein in propane-diol operons with the same structure.	1.43157e-91
NZ_CP023410.1\|WP_078233486.1\|2203166_2203655_-\|DUF2691-family-protein	gnl\|CDD\|371294	pfam10903, DUF2691, Protein of unknown function (DUF2691). This bacterial family of proteins has no known function.	0.00325712
NZ_CP023410.1\|WP_078233483.1\|2205404_2207045_-\|EAL-domain-containing-protein	gnl\|CDD\|225110	COG2200, Rtn, c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms].	2.24049e-53
NZ_CP023410.1\|WP_078233488.1\|2200660_2201119_-\|4Fe-4S-cluster-binding-domain-containing-protein	gnl\|CDD\|379137	pfam13353, Fer4_12, 4Fe-4S single cluster domain. This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.	2.27005e-09
NZ_CP023410.1\|WP_060669957.1\|2210259_2211357_-\|ethanolamine-utilization-protein-EutH	gnl\|CDD\|237906	PRK15086, PRK15086, ethanolamine utilization protein EutH; Provisional.	9.09039e-166
NZ_CP023410.1\|WP_003455851.1\|2212382_2213141_-\|ethanolamine-utilization-protein	gnl\|CDD\|274184	TIGR02536, putative_ethanolamine_utilization_protein, ethanolamine utilization protein. This family of proteins is found in operons for the polyhedral organelle-based degradation of ethanolamine. This family is not found in proteobacterial species which otherwise have the same suite of genes in the eut operon. Proteobacteria have two genes that are not found in non-proteobacteria which may complement this genes function, a phosphotransacetylase (pfam01515) and the EutJ protein (TIGR02529) of unknown function.	2.7194e-73
NZ_CP023410.1\|WP_003477359.1\|2198777_2199563_+\|phosphorylase	gnl\|CDD\|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	2.8494e-23
NZ_CP023410.1\|WP_025649037.1\|2215492_2216971_-\|acetaldehyde-dehydrogenase-(acetylating)	gnl\|CDD\|131570	TIGR02518, Acetaldehyde_dehydrogenase_acetylating, acetaldehyde dehydrogenase (acetylating).	0
NZ_CP023410.1\|WP_003459864.1\|2207961_2208507_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.82566e-09
NZ_CP023410.1\|WP_003455694.1\|2213348_2213984_-\|phosphate-propanoyltransferase	gnl\|CDD\|237899	PRK15070, PRK15070, phosphate propanoyltransferase.	4.63671e-116
NZ_CP023410.1\|WP_003474302.1\|2211963_2212236_-\|EutN/CcmL-family-microcompartment-protein	gnl\|CDD\|377017	pfam03319, EutN_CcmL, Ethanolamine utilisation protein EutN/carboxysome. The crystal structure of EutN contains a central five-stranded beta-barrel, with an alpha-helix at the open end of this barrel (Structure 2HD3). The structure also contains three additional beta-strands, which help the formation of a tight hexamer, with a hole in the center. this suggests that EutN forms a pore, with an opening of 26 Angstrom in diameter on one face and 14 Angstrom on the other face. EutN is involved in the cobalamin-dependent degradation of ethanolamine.	3.53782e-37
NZ_CP023410.1\|WP_003454005.1\|2208939_2209416_-\|glutathione-peroxidase	gnl\|CDD\|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	8.48351e-99

>NZ_CP023410.1|WP_003459864.1|2207961_2208507_-|GNAT-family-N-acetyltransferase
MNLKRINSNDNCFNKAMEIYNGSFPIFERRTMDDQIKALDDINYHFEVIYDKEEIVGILLYWDMGRYKYIEHFAIDSKLRGKNYGSRVLKEFCDHNKNVILEIDPPIDEISIKRLNFYLKLGFKLQDFDYTHPSYRKGCKRHSLKIMTFNHNMPKEDYDTFNILLKRDVMKYSEFKDRLNN
>NZ_CP023410.1|WP_003459816.1|2207358_2207670_-|hypothetical-protein
MKKVLIGVLVFLICIISVFLFFDREEESIVTDVVEKSQYGLLVNYEDGLIAVDTEDAEIIDRDGKENTLDCINEGDRIEIIYDGKIEETYPAQINNVYKIIIF
>NZ_CP023410.1|WP_078233483.1|2205404_2207045_-|EAL-domain-containing-protein
MKKRVFWVSIVFLIIITVLGITIKFDGKKVNCNRKTVKVGFYEYYPYYYLNKNSMPDGYYNEILELICNKLDLNYKYVDCNVTDALEKLKSGQIDLVFGISKTPDREKEYEFTDHYLNNDNFAIYTNKNIKNGDLKALNGLKMGFLKGEENNEWILRLLKDKGINVKPIDVSNYPEDEEYLHDNKVDFVVENTRSNINYENKNIKKIFEFSSGPVYITSRKGNEKLIEGIDSVLGELEEDGEQKDTNLYSKYFDEHLDKLKNEKLLVVIFLIIISLFIYKKRKNKIFAIRTKRKIRDYMKNDKYILYYQPIVDPKTNGVKGFESLLRLNKDGKILTPYSFIREIEDNNMSLEVSLWLLKKVILDYRIIKDYDMVKGRDFYISLNVSFKEIENPKFLRSLMKIAKDYKIDDCNICLEIVEKFGMEDIGRIQSAIRIIKEYGFLIAIDDFGVEYSNLDLLNKIDSDIVKLDKYFADNLDKSIINEKTVEFISEICIIANRTIVFEGIEEQYQVDIVKAFPYEKIYIQGYFYSKLVDIETLKDFKFKDS
>NZ_CP023410.1|WP_078233484.1|2204702_2205323_-|flavodoxin-family-protein
MKVLLVNGSPNKEGCTYTALKEVSKTLEENGIDTEIFQVGNKPIGGCIGCGSCKKTGECFMKDGVNEFVEKAKDADGFVFGSPVYYAAASGSITSFLDRAFYSGGKHMAFKPGAVICSARCAGTTSTLDQLSKYLTICNMPVVSSQYWNMVHGNTPEEVKKDLEGMQTMRVLGRNMAWLIKCIELGKNNNILKPELEERERTNFIR
>NZ_CP023410.1|WP_078233485.1|2203834_2204260_-|hypothetical-protein
MESKEMRLAKKAKKLIDEFERVQSVLLNGELSDQEVEIRDDGATIVLKNIMPGYSGEAMFKLTHISDVVKAYIDDMDEENDEMIKSYEVENTNWHESDLGDIYRESTMEHLEKVEVVGDKVRHTYKELKKIEEKAREIEGL
>NZ_CP023410.1|WP_078233486.1|2203166_2203655_-|DUF2691-family-protein
MRGIVLDKGQEYYTNLRKVFKAFNNIHLEYNWLITDCCAYPENEDIEELLSREYCFISGEELDTIIKKEDFQLIWGVLSGFNKKFTLEEIMKYTLPYAEDNKDIWENPVCIQHPLSEIEIISWDSDKTVLISKDENLLGSFKSNFHLSEDLEFYNRKLKNRL
>NZ_CP023410.1|WP_078233487.1|2201115_2202927_-|ribonucleoside-triphosphate-reductase
MYNVSINKRDVKKDVKNMLSSKKIVDDYIKKIDWRVNENSNSPYSFGSLNKHIIAEVSKDYWLNEVYKDKRIIDAYKNGDMHIHDLGGLTLYCCGYSLRNIILMGVQGIPNIPTSSPAKHFDAILNQIANLVTIYQNEIMGAVAFNSFDTLLAPYIKKDNLTYEEVKQNLQNFIFSINSNSRAGAEPAFTNITFDLFPPKDLENDPALIGDKIQEFTYKECQKEMDMLNKAFYELMNEGDYNGRPFSYPIPTYNINSNFDFDNPNNDMLFEMTGKFGYPYFANFVNSDMDQSDVRSMCCRLNLDLRELRKRNGGLFGSGDSTGSIGVVTINLPRLAYKYKNNEKEFFNALKEILIIAKDSLEKKRKWLNDNIINKDMLPAFSTYVGTLKNHFSTIGIVGLNEMCENFNGNNILTEEGMEFSIKVCNFIREELINFQEETGNLYNFEATPAESTCYRLAKKDVEDFEDIIVRGGREYPYYTNSCHMPPNEVKNLKQLFDHQEKLQVLFTGGTVVHIYCDGAISGEKAKHIVKTVCKKYRTPYVSISPLNRYCEEHGYVKERVEECPICGKKLDLYQRITGYLRKVEFFNDGKKSEFKDRNQLSL
>NZ_CP023410.1|WP_078233488.1|2200660_2201119_-|4Fe-4S-cluster-binding-domain-containing-protein
MIIKTKGIVHERVEDAPFMGALISAVDCNLNCKGCFNQHLKDLPNIEMDSEDILDKVTNDPFNEGIILAGLEWSLQPKELREMINSARKRKLKVIVYSGLSEEEFKKKFPDIYGLKGDMYFKFGKYDEKLKVNNNIQYDVKLATSNQKILKK
>NZ_CP023410.1|WP_003459849.1|2200277_2200496_+|hypothetical-protein
MKDEKINIKYQNKVNLIFIILVTISFLLYRFGFDKNGNLLSLNYILIYFVVLVLVISSLKNFIREKSKNKNN
>NZ_CP023410.1|WP_003477359.1|2198777_2199563_+|phosphorylase
MYNFLIAGHTKYGLKKDTLCKSVLKCDDEAIKENVIIAPWWEPTIFKDIESELIVDTSIKIWNCKLFDKNITYIKTGIGASVCTDVILALGNSNCKKIIFIGSVGALDEKINIGDIIIPTLSVCGDGVCRYLEKDLTKDCFGEKYYPDTKLNKILIKNTEKICKDNNISYHIVPNFSVDTIFAQFAHLDYIMKLGCKSIEMETAAAFKACSICNIPIAAIFNVSDNSIKNKSIYNGKTESELKYRKKVRNEIIPKIIYSLL
>NZ_CP023410.1|WP_003454005.1|2208939_2209416_-|glutathione-peroxidase
MEIYDISVKDINGENVSLERYRGKVLLIVNTASKCGFTKQFDGLEELYEKYKDEGFEVLGFPCNQFKEQDPGSNSEIMNFCKLNFGVTFPMFEKIDVNGENESLLYSYLKEQKSGMFGSKIKWNFTKFLVDREGNVIKRFSPQTTPKSIEKDIEELLA
>NZ_CP023410.1|WP_087327787.1|2209783_2210263_-|DUF861-domain-containing-protein
MIMENISKELLEKLVRQIIEEKLAGAGNNDSVDFIRNKDKSGIMSIKLPTVKVDESNRLDTGNPRDVVYTKDLFTLEESPRLGAGIMEMKETTFDWTLNYDEIDYVIEGHLDIIIDGRKISADAGEIILIPKGSKIQFSVPDYARFIYVTYPADWASQA
>NZ_CP023410.1|WP_060669957.1|2210259_2211357_-|ethanolamine-utilization-protein-EutH
MSINEIIVYIMVACMALGAIDKCLGNKFGIGEQFEEGIMAMGSLALAMVGVICLAPVLASVLGPIVTPVFNALGADPAMFAGSILANDMGGAPLAASLAQDPQAGMFSGLIIGAMMGATIVFTIPVSLGIIEKKDHKFLATGILAGIITIPVGAFVGGLVAGFPAMMVLKNLVPIIIFAILIAIGLAFAEEAMIKGFNIFGKIVVIIITLALAAAIIEALTGIVIIPGMNPISEGIEIVGDIAIVLAGAFPLVYIITKVFKKPLMGLGKILGINEIAAAGMIASLANNIPMFGMLKDMDDRGKIINVAFAVSASFVLGDHLGFTAGFNPEMIFPMIVAKLVGGITAVILAMFIAKKTLGKIEEAK
>NZ_CP023410.1|WP_003477263.1|2211407_2211962_-|BMC-domain-containing-protein
MKKSIGALEFRSISKGIEVSNEVVKKAFVEVSYLKSICPGKFFLIVNGDAGEVKEAIEFGEKLGEKYLVGSFIINSIHHDIINALKGKYSQKNIEDKAIGIMETGKVSSGILALDKTLKSSEVNLVKLQLAFGIGGKLVYIVSGDLSSVENGMREGQAILQEKDIINVSIIPFVHSEIAKNLIK
>NZ_CP023410.1|WP_003474302.1|2211963_2212236_-|EutN/CcmL-family-microcompartment-protein
MEIGRVVGNVWATRKDEKLNGQKFLIVKLLISKDKEKEGLFVAADNAGAGIGDIVLITKGGAARQSIGNREVPIDAAIVGIVDSIDIEED
>NZ_CP023410.1|WP_003455851.1|2212382_2213141_-|ethanolamine-utilization-protein
MKGGKDNMDYEKLVEFLVDEIYKRIQEENSKSNSLEKRKSIVVIGESNVSFYREALKGFDINPLTSECKDCDILLISKLCIKGLSNIAQGTCTTKAENFALEMLLKGKKVYILEDGIEYRKYKNTAPKVLYNKYIKFEEELLAYGIEVIDDLNRISIESKDEKVSFSGIKEEISKNLCLCSENKVEGKKDLDTTAIADEFTINLSNKKLVSESDLRKPHINGVRTLIVDKKAIITPLAKDYIRINNLNVVLS
>NZ_CP023410.1|WP_003455694.1|2213348_2213984_-|phosphate-propanoyltransferase
MDNLLQDIIEEVVRRVKDEAFIEVEASGRHVHLTREHIEILFGEGHELTRIKDLSQPGQYACKERVTISGPRGKIDNVVVLGPPRNETQVEVSFTDALVLGSIPPVKLSGDLENTPEITISTERASIALNRGLMVAKRHIHMTPEDAIKFGVSNNESVKVKVLGKRPLIFDDVIVRVSKDYRTFMHIDYDEANACGFSKGTFALIVGKDEK
>NZ_CP023410.1|WP_003453880.1|2213993_2214770_-|ethanolamine-utilization-cobalamin-adenosyltransferase
MAVLTEGEVRKRLSREDLKALKEFKVVKGEIITPSAKSYLAEHNINLVYVNSEEEKLNKETEPKEIIREVVREKEYKYETVFGAKLDEKPEHMTHLTGNLLVFKDHKRIIFRGKIDSLEARIVETQVLCHKQGMNKLVEDLQEILNLIGRILRCEVLSEPLEGFSLQGMTEKDLREKSHNPKKYFGIGHEMPTYEMGEIVAALNILRTLTRETELSAYEAFKGEYGQVEREDLIRALNRLSSVFWIMIFKVRTGKYEK
>NZ_CP023410.1|WP_003453976.1|2214847_2215138_-|ethanolamine-utilization-microcompartment-protein-EutM
MANANALGMIETRGLVGAIEAADAMVKAANVQLVGKEQVGGGLVTVMVRGDVGAVKAATDAGAAAAERVGDLISVHVIPRPHFEVDAILPKAPKAE
>NZ_CP023410.1|WP_025649037.1|2215492_2216971_-|acetaldehyde-dehydrogenase-(acetylating)
MEFLDKDLVSIQETRGLIRKAKEAQSKLARMSQQDIDRIVKAISDAAYENSEKLAKMANEETGFGKWEDKVLKNVFAARTVYESIKDTKTVGIVEENVEKRAFKIMVPVGVVAGLIPSTNPTSTAIYKAMISIKARNAIVLSPHPSAKKCIIETAKIIAKAAERAGCPEGAIGCITVPSIEGTNELMKNKDTSLILATGGEAMVRAAYSSGTPAIGVGPGNGPAFIDKSADVKLAVKRILDSKTFDNGTICASEQSIVVEKAMEDEVVRELKEQGAYFLTEEQANQLSKFVMRANGTMNPQIVGKTPQDIAKLAGLEGIPSWARVLVPRECHVGHKYPFSREKLTTILTFFVEENVDAVLNRCREILLNEGAGHTFCMHANNEELVKRFALEMPVSRMVVNSPGALGGIGATINLVPALTLGCGAVGGSSTSHNIGPLDLMNTRNVAYGVRELEDIRELAVGATKEVASSLDLGDKEELINLLVKKIIEELK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP023410_2	2.30\|2130433\|37\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130433-2130469	37	JQ660954	Clostridium phage PhiS63, complete genome	15820-15856	0	1.0
NZ_CP023410_2	2.6\|2128876\|37\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2128876-2128912	37	JQ660954	Clostridium phage PhiS63, complete genome	24003-24039	1	0.973
NZ_CP023410_2	2.13\|2129331\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2129331-2129366	36	JQ660954	Clostridium phage PhiS63, complete genome	13947-13982	2	0.944
NZ_CP023410_2	2.26\|2130173\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130173-2130208	36	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	33147-33182	7	0.806
NZ_CP023410_2	2.27\|2130238\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130238-2130273	36	GQ443085	Clostridium phage CP26F, complete genome	13130-13165	7	0.806
NZ_CP023410_2	2.27\|2130238\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130238-2130273	36	JF767210	Clostridium phage phi9O, complete genome	13535-13570	7	0.806
NZ_CP023410_2	2.27\|2130238\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130238-2130273	36	NC_019496	Clostridium phage phiCP26F, complete genome	13130-13165	7	0.806
NZ_CP023410_2	2.31\|2130499\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130499-2130534	36	NZ_MK275620	Clostridium perfringens strain JXJA17 plasmid p2, complete sequence	26649-26684	7	0.806
NZ_CP023410_2	2.31\|2130499\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130499-2130534	36	NZ_MK275623	Clostridium perfringens strain JXJA17 plasmid p5, complete sequence	1679-1714	7	0.806
NZ_CP023410_2	2.31\|2130499\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130499-2130534	36	NC_008265	Clostridium phage phiSM101, complete genome	30846-30881	7	0.806
NZ_CP023410_2	2.26\|2130173\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130173-2130208	36	MN694016	Marine virus AFVG_250M811, complete genome	27695-27730	8	0.778
NZ_CP023410_2	2.26\|2130173\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130173-2130208	36	MN693920	Marine virus AFVG_250M810, complete genome	27308-27343	8	0.778
NZ_CP023410_2	2.26\|2130173\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130173-2130208	36	MN693800	Marine virus AFVG_250M813, complete genome	27575-27610	8	0.778
NZ_CP023410_2	2.26\|2130173\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130173-2130208	36	MN694453	Marine virus AFVG_250M327, complete genome	5479-5514	8	0.778
NZ_CP023410_2	2.26\|2130173\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130173-2130208	36	MN694554	Marine virus AFVG_250M812, complete genome	27597-27632	8	0.778
NZ_CP023410_2	2.12\|2129267\|35\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2129267-2129301	35	KU878088	Bacillus phage AR9, complete genome	99311-99345	9	0.743
NZ_CP023410_2	2.12\|2129267\|35\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2129267-2129301	35	MF360957	Bacillus virus PBS1, complete genome	9614-9648	9	0.743
NZ_CP023410_2	2.29\|2130368\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130368-2130403	36	NZ_CP045340	Vibrio sp. THAF190c plasmid pTHAF190c_b, complete sequence	447163-447198	9	0.75
NZ_CP023410_2	2.2\|2128616\|36\|NZ_CP023410\|CRISPRCasFinder,CRT	2128616-2128651	36	NC_013862	Allochromatium vinosum DSM 180 plasmid pALVIN02, complete sequence	35332-35367	10	0.722
NZ_CP023410_2	2.6\|2128876\|37\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2128876-2128912	37	NC_011253	Borrelia recurrentis A1 plasmid pl33, complete sequence	29932-29968	10	0.73
NZ_CP023410_2	2.6\|2128876\|37\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2128876-2128912	37	NC_011258	Borrelia recurrentis A1 plasmid pl37, complete sequence	27319-27355	10	0.73
NZ_CP023410_2	2.6\|2128876\|37\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2128876-2128912	37	NC_011260	Borrelia recurrentis A1 plasmid pl53, complete sequence	42935-42971	10	0.73
NZ_CP023410_2	2.24\|2130043\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130043-2130078	36	NZ_CP046630	Streptococcus equinus strain CNU G6 plasmid p1_CNU_G6, complete sequence	2865-2900	10	0.722
NZ_CP023410_2	2.24\|2130043\|36\|NZ_CP023410\|CRISPRCasFinder,CRT,PILER-CR	2130043-2130078	36	NZ_CP046920	Streptococcus sp. CNU G2 plasmid p_CNU_G2, complete sequence	6529-6564	10	0.722

1. spacer 2.30|2130433|37|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 0, identity: 1.0

ccatagcttccctctttatttttaagattataaataa	CRISPR spacer
ccatagcttccctctttatttttaagattataaataa	Protospacer
*************************************

2. spacer 2.6|2128876|37|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 1, identity: 0.973

catggaaaagaaaagatataaagaaaagtaaaactcc	CRISPR spacer
catggaaacgaaaagatataaagaaaagtaaaactcc	Protospacer
******** ****************************

3. spacer 2.13|2129331|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 2, identity: 0.944

taataaagtttataacatagatattcgttcagacaa	CRISPR spacer
gaacaaagtttataacatagatattcgttcagacaa	Protospacer
 **.********************************

4. spacer 2.26|2130173|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 7, identity: 0.806

ttttgaaagtatatttaaacaattattaaatattta	CRISPR spacer
atttgaaagtatatttaagcaattattattttgtaa	Protospacer
 *****************.*********  *  * *

5. spacer 2.27|2130238|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to GQ443085 (Clostridium phage CP26F, complete genome) position: , mismatch: 7, identity: 0.806

tacttgtaccaattatagcattttcaaagctaacat	CRISPR spacer
tacttgtaccacttaaagcattttcaaatgatatat	Protospacer
*********** *** ************    *.**

6. spacer 2.27|2130238|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to JF767210 (Clostridium phage phi9O, complete genome) position: , mismatch: 7, identity: 0.806

tacttgtaccaattatagcattttcaaagctaacat	CRISPR spacer
tacttgtaccacttaaagcattttcaaatgatatat	Protospacer
*********** *** ************    *.**

7. spacer 2.27|2130238|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NC_019496 (Clostridium phage phiCP26F, complete genome) position: , mismatch: 7, identity: 0.806

tacttgtaccaattatagcattttcaaagctaacat	CRISPR spacer
tacttgtaccacttaaagcattttcaaatgatatat	Protospacer
*********** *** ************    *.**

8. spacer 2.31|2130499|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MK275620 (Clostridium perfringens strain JXJA17 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.806

tatacttagtatttcttagtattactttacaataat	CRISPR spacer
cattacaagtattacttagtatcactttacaataat	Protospacer
.**  . ****** ********.*************

9. spacer 2.31|2130499|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MK275623 (Clostridium perfringens strain JXJA17 plasmid p5, complete sequence) position: , mismatch: 7, identity: 0.806

tatacttagtatttcttagtattactttacaataat	CRISPR spacer
aattacaagtatcacttagtattactttacaataat	Protospacer
 **  . *****. **********************

10. spacer 2.31|2130499|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NC_008265 (Clostridium phage phiSM101, complete genome) position: , mismatch: 7, identity: 0.806

tatacttagtatttcttagtattactttacaataat	CRISPR spacer
cattacaagtattctttagtattactttacaataat	Protospacer
.**  . ******..*********************

11. spacer 2.26|2130173|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to MN694016 (Marine virus AFVG_250M811, complete genome) position: , mismatch: 8, identity: 0.778

---ttttgaaagtatatttaaacaattattaaatattta	CRISPR spacer
ataatttg---gtatatttaaataattattatatattgt	Protospacer
    ****   ***********.******** *****

12. spacer 2.26|2130173|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to MN693920 (Marine virus AFVG_250M810, complete genome) position: , mismatch: 8, identity: 0.778

---ttttgaaagtatatttaaacaattattaaatattta	CRISPR spacer
ataatttg---gtatatttaaataattattatatattgt	Protospacer
    ****   ***********.******** *****

13. spacer 2.26|2130173|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to MN693800 (Marine virus AFVG_250M813, complete genome) position: , mismatch: 8, identity: 0.778

---ttttgaaagtatatttaaacaattattaaatattta	CRISPR spacer
ataatttg---gtatatttaaataattattatatattgt	Protospacer
    ****   ***********.******** *****

14. spacer 2.26|2130173|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to MN694453 (Marine virus AFVG_250M327, complete genome) position: , mismatch: 8, identity: 0.778

---ttttgaaagtatatttaaacaattattaaatattta	CRISPR spacer
ataatttg---gtatatttaaataattattatatattgt	Protospacer
    ****   ***********.******** *****

15. spacer 2.26|2130173|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to MN694554 (Marine virus AFVG_250M812, complete genome) position: , mismatch: 8, identity: 0.778

---ttttgaaagtatatttaaacaattattaaatattta	CRISPR spacer
ataatttg---gtatatttaaataattattatatattgt	Protospacer
    ****   ***********.******** *****

16. spacer 2.12|2129267|35|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to KU878088 (Bacillus phage AR9, complete genome) position: , mismatch: 9, identity: 0.743

aaaatggaaaagtattattgttcttttggtttcgt	CRISPR spacer
taaatgtaaaagtattattattctttaatttattt	Protospacer
 ***** ************.****** . ** . *

17. spacer 2.12|2129267|35|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to MF360957 (Bacillus virus PBS1, complete genome) position: , mismatch: 9, identity: 0.743

aaaatggaaaagtattattgttcttttggtttcgt	CRISPR spacer
taaatgtaaaagtattattattctttaatttattt	Protospacer
 ***** ************.****** . ** . *

18. spacer 2.29|2130368|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045340 (Vibrio sp. THAF190c plasmid pTHAF190c_b, complete sequence) position: , mismatch: 9, identity: 0.75

ctagcttcaattccatctttactccaaatatcaact	CRISPR spacer
ctagtttgaattccatctttactccattgacagaca	Protospacer
****.** ******************   *. .**

19. spacer 2.2|2128616|36|NZ_CP023410|CRISPRCasFinder,CRT matches to NC_013862 (Allochromatium vinosum DSM 180 plasmid pALVIN02, complete sequence) position: , mismatch: 10, identity: 0.722

cgcttaaatgggaaggcaagggttagagcaaaaaat	CRISPR spacer
tattccgtttggaagccaaggcttagagcaaaaaat	Protospacer
...*. . * ***** ***** **************

20. spacer 2.6|2128876|37|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NC_011253 (Borrelia recurrentis A1 plasmid pl33, complete sequence) position: , mismatch: 10, identity: 0.73

catggaaaagaaaagatataaagaaaagtaaaactcc	CRISPR spacer
gtttttaaagaaaagctataaaaaaaagtaaaacaag	Protospacer
  *   ********* ******.***********

21. spacer 2.6|2128876|37|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NC_011258 (Borrelia recurrentis A1 plasmid pl37, complete sequence) position: , mismatch: 10, identity: 0.73

catggaaaagaaaagatataaagaaaagtaaaactcc	CRISPR spacer
gtttttaaagaaaagctataaaaaaaagtaaaacaag	Protospacer
  *   ********* ******.***********

22. spacer 2.6|2128876|37|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NC_011260 (Borrelia recurrentis A1 plasmid pl53, complete sequence) position: , mismatch: 10, identity: 0.73

catggaaaagaaaagatataaagaaaagtaaaactcc	CRISPR spacer
gtttttaaagaaaagctataaaaaaaagtaaaacaag	Protospacer
  *   ********* ******.***********

23. spacer 2.24|2130043|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046630 (Streptococcus equinus strain CNU G6 plasmid p1_CNU_G6, complete sequence) position: , mismatch: 10, identity: 0.722

ccattacaggatataaaatgtggaaagaagaaggga	CRISPR spacer
atatggaagcatataaaatttggaaagaagaagtag	Protospacer
 .** . ** ********* ************* ..

24. spacer 2.24|2130043|36|NZ_CP023410|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046920 (Streptococcus sp. CNU G2 plasmid p_CNU_G2, complete sequence) position: , mismatch: 10, identity: 0.722

ccattacaggatataaaatgtggaaagaagaaggga	CRISPR spacer
atatggaagcatataaaatttggaaagaagaagtag	Protospacer
 .** . ** ********* ************* ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1287040 : 1300295

Clostridium_phage(22.22%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003481618.1\|1287040_1288624_-	ATP-binding cassette domain-containing protein	A0A1V0SGN0	Hokovirus	1.9e-43	25.4
WP_003451999.1\|1288811_1290110_+	uracil permease	Q9KX94	Enterobacteria_phage	3.6e-69	39.3
WP_003456055.1\|1290535_1291549_+	DUF348 domain-containing protein	A0A143FMI2	Bacillus_phage	3.5e-19	52.0
WP_003468317.1\|1291772_1292060_+	thiamine-binding protein	NA	NA	NA	NA
WP_057231623.1\|1292156_1293170_+	N-acetylmuramoyl-L-alanine amidase	Q8SBN4	Clostridium_phage	1.2e-120	63.4
WP_003465542.1\|1293308_1294019_+	response regulator transcription factor	A0A2R2ZGH8	Clostridioides_phage	2.5e-32	31.8
WP_096071490.1\|1294012_1295335_+	sensor histidine kinase	X5JAC0	Clostridium_phage	2.3e-71	37.3
WP_003457231.1\|1295505_1296381_+	MBL fold metallo-hydrolase	Q332C0	Clostridium_botulinum_C_phage	1.1e-64	50.2
WP_003457240.1\|1296705_1297209_+	QueT transporter family protein	E7DN70	Pneumococcus_phage	1.1e-13	37.2
WP_003474040.1\|1297420_1298773_-	PFL family protein	NA	NA	NA	NA
WP_003454568.1\|1298789_1299059_-	ACT domain-containing protein	NA	NA	NA	NA
WP_003457168.1\|1299257_1300295_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.4e-31	36.0

DBSCAN-SWA_2

1938698 : 1974487

Clostridium_phage(86.67%)

capsid,terminase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003460274.1\|1938698_1939115_-\|holin	phage holin family protein	M9Q253	Clostridium_phage	4.0e-70	99.3
WP_078233613.1\|1945041_1945422_-	DUF1617 family protein	M9Q2L1	Clostridium_phage	2.2e-59	93.7
WP_078233612.1\|1945490_1945757_-	hypothetical protein	M9Q1I4	Clostridium_phage	1.4e-36	86.4
WP_078233611.1\|1945777_1946131_-	hypothetical protein	M9Q2F8	Clostridium_phage	1.9e-57	95.5
WP_078233610.1\|1946134_1949350_-	hypothetical protein	M9Q251	Clostridium_phage	0.0e+00	90.6
WP_078233609.1\|1949390_1949723_-	hypothetical protein	M9Q2I4	Clostridium_phage	6.7e-52	92.7
WP_078233608.1\|1949712_1950081_-	hypothetical protein	M9Q2L0	Clostridium_phage	9.1e-42	74.6
WP_078233607.1\|1950096_1950549_-	hypothetical protein	M9Q1I1	Clostridium_phage	3.8e-74	92.3
WP_011590476.1\|1950558_1950945_-	hypothetical protein	M9Q2F6	Clostridium_phage	5.0e-67	96.9
WP_078233606.1\|1950944_1951328_-	hypothetical protein	M9Q249	Clostridium_phage	8.0e-65	97.6
WP_011590474.1\|1951327_1951654_-	hypothetical protein	M9Q2I3	Clostridium_phage	5.2e-57	99.1
WP_011590473.1\|1951657_1952020_-	hypothetical protein	M9Q2K9	Clostridium_phage	3.9e-61	98.3
WP_003460293.1\|1952055_1952325_-	hypothetical protein	M9Q1H8	Clostridium_phage	3.4e-22	100.0
WP_078233605.1\|1952341_1953247_-\|capsid	capsid protein	M9Q2F4	Clostridium_phage	8.2e-169	98.0
WP_096071611.1\|1953270_1953879_-	hypothetical protein	M9Q248	Clostridium_phage	3.7e-80	88.6
WP_096071612.1\|1953993_1954959_-	hypothetical protein	NA	NA	NA	NA
WP_096071613.1\|1955017_1956262_-\|capsid	capsid protein	M9Q2F2	Clostridium_phage	2.0e-218	91.0
WP_078233601.1\|1956245_1957766_-\|capsid	capsid protein	M9Q246	Clostridium_phage	6.4e-283	96.8
WP_096071614.1\|1957767_1957977_-	hypothetical protein	NA	NA	NA	NA
WP_096071615.1\|1957979_1959347_-\|terminase	terminase	M9Q2I1	Clostridium_phage	3.2e-265	97.4
WP_078233599.1\|1959339_1959768_-\|terminase	terminase small subunit	A0A0A8WDX8	Clostridium_phage	4.2e-30	52.1
WP_078233598.1\|1959760_1960054_-	hypothetical protein	NA	NA	NA	NA
WP_078233597.1\|1960115_1960334_-	hypothetical protein	NA	NA	NA	NA
WP_078233596.1\|1960809_1961256_-	hypothetical protein	NA	NA	NA	NA
WP_078233595.1\|1961310_1961844_-	hypothetical protein	Q8SBL1	Clostridium_phage	3.2e-19	34.9
WP_078233594.1\|1961853_1962045_-	hypothetical protein	NA	NA	NA	NA
WP_078233593.1\|1962046_1962232_-	hypothetical protein	NA	NA	NA	NA
WP_078233592.1\|1962231_1962603_-	hypothetical protein	B4XYT8	Lactobacillus_phage	2.6e-12	36.6
WP_078233591.1\|1962595_1962850_-	hypothetical protein	NA	NA	NA	NA
WP_078233590.1\|1962850_1963267_-	hypothetical protein	NA	NA	NA	NA
WP_078233589.1\|1963415_1963736_-	hypothetical protein	NA	NA	NA	NA
WP_078233588.1\|1963738_1963942_-	hypothetical protein	NA	NA	NA	NA
WP_078233587.1\|1963944_1964253_-	hypothetical protein	M9Q2L5	Clostridium_phage	8.7e-22	54.2
WP_078233586.1\|1964286_1964499_-	hypothetical protein	NA	NA	NA	NA
WP_078233585.1\|1964500_1965220_-	hypothetical protein	A0A2P1JTY8	Anoxybacillus_phage	2.0e-32	57.0
WP_078233584.1\|1965232_1965415_-	hypothetical protein	NA	NA	NA	NA
WP_078233583.1\|1965426_1966209_-	hypothetical protein	A0A0A7RUC1	Clostridium_phage	1.8e-100	67.3
WP_078233581.1\|1967084_1968767_-	AAA family ATPase	R9TQJ2	Paenibacillus_phage	1.8e-108	41.6
WP_003449265.1\|1969111_1969357_-	hypothetical protein	NA	NA	NA	NA
WP_078233580.1\|1969359_1969539_-	hypothetical protein	I2E8Z1	Clostridium_phage	1.5e-05	36.8
WP_078233579.1\|1969528_1969762_-	hypothetical protein	NA	NA	NA	NA
WP_078233578.1\|1969775_1969955_-	hypothetical protein	M9Q2G4	Clostridium_phage	2.6e-18	81.4
WP_153302651.1\|1969948_1970119_-	hypothetical protein	NA	NA	NA	NA
WP_078233577.1\|1970306_1970516_+	hypothetical protein	NA	NA	NA	NA
WP_153302650.1\|1970487_1970655_-	hypothetical protein	NA	NA	NA	NA
WP_078233576.1\|1970696_1971446_-	hypothetical protein	A0A2D1GQG9	Lysinibacillus_phage	9.5e-46	45.1
WP_078233575.1\|1971456_1971672_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_078233573.1\|1972402_1972918_+	ImmA/IrrE family metallo-endopeptidase	Q8SBN1	Clostridium_phage	4.4e-34	46.1
WP_078233572.1\|1972990_1974487_+	recombinase family protein	M9Q2G2	Clostridium_phage	8.5e-62	32.6

DBSCAN-SWA_3

2473441 : 2486031

Synechococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011590302.1\|2473441_2474947_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.2e-66	47.2
WP_003468450.1\|2474959_2475574_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.2e-24	38.3
WP_003468449.1\|2475561_2476563_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	6.7e-71	49.0
WP_011009969.1\|2476563_2478009_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.4e-56	33.0
WP_003456948.1\|2478030_2478738_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	2.8e-47	43.8
WP_003453078.1\|2478737_2479217_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.6e-28	47.4
WP_003457110.1\|2479527_2483328_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	4.7e-32	24.9
WP_003456962.1\|2483565_2484876_-	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_003457021.1\|2485380_2486031_-	aminotransferase	A0A1B1P8C0	Bacillus_phage	2.9e-14	31.1

DBSCAN-SWA_4

2521465 : 2549920

Streptococcus_phage(80.95%)

integrase,transposase

attL 2513217:2513233|attR 2554844:2554860

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2513217:2513233	attL	NA	NA	NA	NA
WP_032547211.1\|2521465_2521792_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	2.5e-35	65.7
WP_054344453.1\|2521808_2522195_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	1.7e-38	65.4
WP_069432092.1\|2522394_2523036_+	chloramphenicol acetyltransferase	A0A1X9I6V6	Streptococcus_phage	1.8e-32	32.5
WP_069432091.1\|2523110_2524490_+	cell division protein FtsK	A0A1S5SFB5	Streptococcus_phage	7.3e-169	64.2
WP_069432098.1\|2524497_2524902_+	hypothetical protein	NA	NA	NA	NA
WP_110077255.1\|2525112_2526333_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-148	63.0
WP_010817889.1\|2526348_2526489_+	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_010817890.1\|2526485_2526707_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	6.2e-30	91.8
WP_010817891.1\|2526904_2527315_+	hypothetical protein	NA	NA	NA	NA
WP_078233396.1\|2527331_2527778_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_076779928.1\|2527804_2528218_+	DUF3788 domain-containing protein	NA	NA	NA	NA
WP_010817896.1\|2528341_2528578_+	hypothetical protein	NA	NA	NA	NA
WP_010817897.1\|2528552_2529050_+	hypothetical protein	NA	NA	NA	NA
WP_010817898.1\|2529067_2529571_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.1e-53	59.0
WP_010817899.1\|2529681_2530071_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	6.9e-48	73.0
WP_010817900.1\|2530057_2532505_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.3
WP_010817901.1\|2532504_2534631_+	YtxH domain-containing protein	A0A1S5SF30	Streptococcus_phage	1.5e-192	63.3
WP_078233395.1\|2534627_2535635_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	6.6e-127	72.6
WP_010817903.1\|2535650_2536544_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	2.0e-79	52.7
WP_010817904.1\|2536671_2537046_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010817905.1\|2537047_2537905_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.3e-22	33.2
WP_010817906.1\|2537907_2538549_+	ABC-2 transporter permease	NA	NA	NA	NA
WP_010817907.1\|2538566_2538953_+	hypothetical protein	NA	NA	NA	NA
WP_002576326.1\|2539269_2539623_-	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	2.7e-19	40.7
WP_009246557.1\|2539788_2539986_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002576325.1\|2539975_2540590_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002576324.1\|2540770_2541688_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	6.0e-42	43.2
WP_002576323.1\|2541680_2542430_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_002576322.1\|2542429_2543257_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_078233394.1\|2543424_2543907_+	RNA polymerase subunit sigma-70	NA	NA	NA	NA
WP_050563598.1\|2543929_2544337_+	winged helix-turn-helix domain-containing protein	W8CYM9	Bacillus_phage	4.0e-06	33.7
WP_010817908.1\|2544477_2544717_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_078234315.1\|2544721_2545324_+	DUF998 domain-containing protein	NA	NA	NA	NA
WP_078233393.1\|2545376_2545775_+	winged helix-turn-helix transcriptional regulator	W8CYM9	Bacillus_phage	9.6e-05	33.3
WP_010817911.1\|2545814_2546177_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_025189641.1\|2546328_2546553_+	hypothetical protein	NA	NA	NA	NA
WP_010817913.1\|2546572_2546938_+	hypothetical protein	NA	NA	NA	NA
WP_010817914.1\|2547377_2547803_+	DNA-directed RNA polymerase sigma-70 factor	A0A1S5SEW0	Streptococcus_phage	4.4e-16	38.3
WP_010817915.1\|2547792_2548038_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	4.2e-11	44.9
WP_074087813.1\|2548123_2548348_-\|transposase	transposase	NA	NA	NA	NA
WP_010817916.1\|2548437_2548644_+	excisionase family DNA-binding domain-containing protein	A0A1S5SF07	Streptococcus_phage	1.3e-24	82.8
WP_010817917.1\|2548723_2549920_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	1.4e-155	67.0
2554844:2554860	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP023413

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 10014

Bacillus_phage(33.33%)

integrase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004456826.1\|790_1075_+	hypothetical protein	NA	NA	NA	NA
WP_003465044.1\|1075_1387_+	hypothetical protein	NA	NA	NA	NA
WP_004456857.1\|1762_2563_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_004456849.1\|2624_4214_+	DUF87 domain-containing protein	M4ZS25	Bacillus_phage	4.0e-17	29.8
WP_025648669.1\|4390_5470_+	TcpC	NA	NA	NA	NA
WP_025648670.1\|5481_5829_+	hypothetical protein	NA	NA	NA	NA
WP_003453383.1\|5840_6209_+	TcpE	NA	NA	NA	NA
WP_096071800.1\|6484_9010_+	TcpF	A0A1S5SF64	Streptococcus_phage	1.2e-68	27.3
WP_003464374.1\|9009_10014_+	cell wall-binding protein	A0A0A7RUS8	Clostridium_phage	3.1e-36	50.0

DBSCAN-SWA_2

15147 : 16167

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003464366.1\|15147_16167_+	DNA (cytosine-5-)-methyltransferase	A0A0E3DF50	Bacillus_phage	1.5e-57	39.6

DBSCAN-SWA_3

22347 : 29631

Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003474254.1\|22347_23205_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	E9P639	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.6e-17	30.3
WP_003479690.1\|23959_25222_+	tetracycline efflux MFS transporter TetA(P)	NA	NA	NA	NA
WP_003479689.1\|25205_27164_+	tetracycline resistance ribosomal protection protein TetB(P)	D0R0F5	Streptococcus_phage	1.6e-124	40.4
WP_003479688.1\|27355_27634_+	hypothetical protein	NA	NA	NA	NA
WP_003479685.1\|28896_29631_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	1.4e-17	39.5

DBSCAN-SWA_4

36775 : 37636

Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015060558.1\|36775_37636_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	E9P639	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-18	31.0

DBSCAN-SWA_5

45695 : 46466

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096071807.1\|45695_46466_+	diguanylate cyclase	G3MA91	Bacillus_virus	4.0e-15	35.7

DBSCAN-SWA_6

58348 : 62526

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015060513.1\|58348_58879_+	transcriptional regulator	D2XR36	Bacillus_phage	9.8e-05	46.6
WP_003474956.1\|59164_59392_+	hypothetical protein	NA	NA	NA	NA
WP_025648664.1\|59457_59952_+	hypothetical protein	NA	NA	NA	NA
WP_003448998.1\|60008_60272_-	hypothetical protein	NA	NA	NA	NA
WP_096071811.1\|60250_61177_-	ParM/StbA family protein	NA	NA	NA	NA
WP_096071812.1\|61713_62526_+	plasmid replication protein	Q0SPH7	Clostridium_phage	2.1e-67	54.2

DBSCAN-SWA_7

65876 : 66251

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003474966.1\|65876_66251_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A291I9M9	Lactobacillus_phage	2.0e-12	33.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP023410

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP023413

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection