CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP023435	Mycobacterium sp. PYR15 chromosome, complete genome	1 crisprs	csa3,cas3,WYL,DEDDh,DinG	1	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP023435_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023435_1

4446930-4447323

Orphan

Consensus_repeat	Method
CGGCGGCCTGCTCATCGGCAACGGC	CRISPRCasFinder

6 spacers

The CRISPR arrays of NZ_CP023435_1

>merge|NZ_CP023435|1|4446930-4447323|CRISPRCasFinder
CGTCGCGGAGTTCATCGGCAACGGCACTGCCGAGCACCCCAACGGCGGCCTGCTCATCGGCAACGGCTACAGCTACAGCGCCGCTGATGCGCAGTGCGCCAGTGCATCCTGCAACGGCGGCCGCGGCGGCCTGCTCATGGGCAACGGCGGTAACGGCTACAACGGCGGCAACGGTGGCAGCGCCGGGCTGTACGGCAACGGCGGCAACGGCGGCGACGCCCTGAGCGCCGCCATCAACGGCGGCAAGGGTGGCAACGGCGGCAACGGCGGACTGGTCGCGGGCAACTCCGCCTCCGGTGCGCTGTTCAGTGGCGGCGGCGGCAACGGCGGCAAGGGTATCGCCGGCGGCGCCGGCGGTAACGGCGGAAACGCCGGCCCGTTCGCCGGTAGCGGC

>NZ_CP023435|1|1|4446930-4447323|CRISPRCasFinder
CGTCGCGGAGTTCATCGGCAACGGC	ACTGCCGAGCACCCCAA
CGGCGGCCTGCTCATCGGCAACGGC	TACAGCTACAGCGCCGCTGATGCGCAGTGCGCCAGTGCATCCTGCAACGGCGGCCG
CGGCGGCCTGCTCATGGGCAACGGC	GGTAACGGCTACAACGGCGGCAACGGTGG
CAGCGCCGGGCTGTACGGCAACGGC	GGCAACGGCGGCGACGCCCTGAGCGCCGCCATCAACGGCGGCAAGGGTGGCAACGGCGGCAA
CGGCGGACTGGTCGCGGGCAACTCC	GCCTCCGGTGCGCTGTTCAGTGGCGGCGGCGGCAA
CGGCGGCAAGGGTATCGCCGGCGGC	GCCGGCGGTAACGGCGGAAA
CGCCGGCCCGTTCGCCGGTAGCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023435.1\|WP_071942471.1\|4448241_4448775_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023435.1\|WP_071942485.1\|4442637_4442922_-\|DUF1330-domain-containing-protein	unknown	unknown	gnl\|CDD\|377765
NZ_CP023435.1\|WP_099973839.1\|4445642_4445906_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023435.1\|WP_071942463.1\|4452175_4453165_+\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|197226
NZ_CP023435.1\|WP_164520226.1\|4446005_4446509_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023435.1\|WP_071942483.1\|4442996_4444481_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143408
NZ_CP023435.1\|WP_071942491.1\|4440285_4441041_-\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP023435.1\|WP_071942469.1\|4450092_4450779_+\|MspA-family-porin	unknown	unknown	gnl\|CDD\|370360
NZ_CP023435.1\|WP_071942481.1\|4444601_4444862_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023435.1\|WP_125477477.1\|4450802_4451405_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NZ_CP023435.1\|WP_071942457.1\|4454320_4456693_+\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NZ_CP023435.1\|WP_071942487.1\|4441979_4442636_+\|CoA-transferase-subunit-B	unknown	unknown	gnl\|CDD\|188219
NZ_CP023435.1\|WP_071942461.1\|4453157_4453733_+\|chromate-transporter	unknown	unknown	gnl\|CDD\|224970
NZ_CP023435.1\|WP_071942479.1\|4444863_4445646_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|236210
NZ_CP023435.1\|WP_071942459.1\|4453729_4454275_+\|chromate-transporter	unknown	unknown	gnl\|CDD\|376780
NZ_CP023435.1\|WP_071949661.1\|4449200_4449884_+\|MspA-family-porin	unknown	unknown	gnl\|CDD\|370360
NZ_CP023435.1\|WP_071942489.1\|4441218_4441980_+\|CoA-transferase-subunit-A	unknown	unknown	gnl\|CDD\|224702
NZ_CP023435.1\|WP_071942465.1\|4451491_4452085_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023435.1\|WP_096312971.1\|4456742_4458602_+\|CocE/NonD-family-hydrolase	unknown	unknown	gnl\|CDD\|273375
NZ_CP023435.1\|WP_071942493.1\|4438610_4440188_-\|methylmalonyl-CoA-mutase	unknown	unknown	gnl\|CDD\|239652

Protein	Function_ID	Function_description	E-value
NZ_CP023435.1\|WP_071942485.1\|4442637_4442922_-\|DUF1330-domain-containing-protein	gnl\|CDD\|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	1.92111e-32
NZ_CP023435.1\|WP_071942469.1\|4450092_4450779_+\|MspA-family-porin	gnl\|CDD\|370360	pfam09203, MspA, MspA. MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel.	1.67348e-44
NZ_CP023435.1\|WP_071949661.1\|4449200_4449884_+\|MspA-family-porin	gnl\|CDD\|370360	pfam09203, MspA, MspA. MspA is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel.	1.03942e-55
NZ_CP023435.1\|WP_071942483.1\|4442996_4444481_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143408	cd07089, ALDH_CddD-AldA-like, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like and related proteins. The 6-oxolauric acid dehydrogenase (CddD) from Rhodococcus ruber SC1 which converts 6-oxolauric acid to dodecanedioic acid; and the aldehyde dehydrogenase (locus SSP0762) from Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 and also, the Mycobacterium tuberculosis H37Rv ALDH AldA (locus Rv0768) sequence; and other similar sequences, are included in this CD.	0
NZ_CP023435.1\|WP_071942491.1\|4440285_4441041_-\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.95254e-56
NZ_CP023435.1\|WP_071942463.1\|4452175_4453165_+\|cardiolipin-synthase	gnl\|CDD\|197226	cd09128, PLDc_unchar1_2, Putative catalytic domain, repeat 2, of uncharacterized phospholipase D-like proteins. Putative catalytic domain, repeat 2, of uncharacterized phospholipase D (PLD, EC 3.1.4.4)-like proteins. PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain two HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily. The two motifs may be part of the active site and may be involved in phosphatidyl group transfer.	1.64254e-47
NZ_CP023435.1\|WP_125477477.1\|4450802_4451405_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.000955492
NZ_CP023435.1\|WP_071942457.1\|4454320_4456693_+\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	6.77263e-22
NZ_CP023435.1\|WP_071942487.1\|4441979_4442636_+\|CoA-transferase-subunit-B	gnl\|CDD\|188219	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit. Various members of this family are characterized as the B subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The A subunit represents a different clade in pfam01144.	1.4181e-120
NZ_CP023435.1\|WP_071942461.1\|4453157_4453733_+\|chromate-transporter	gnl\|CDD\|224970	COG2059, ChrA, Chromate transport protein ChrA [Inorganic ion transport and metabolism].	2.63054e-24
NZ_CP023435.1\|WP_071942479.1\|4444863_4445646_+\|SDR-family-oxidoreductase	gnl\|CDD\|236210	PRK08267, PRK08267, SDR family oxidoreductase.	5.67991e-120
NZ_CP023435.1\|WP_071942459.1\|4453729_4454275_+\|chromate-transporter	gnl\|CDD\|376780	pfam02417, Chromate_transp, Chromate transporter. Members of this family probably act as chromate transporters. Members of this family are found in both bacteria and archaebacteria. The proteins are composed of one or two copies of this region. The alignment contains two conserved motifs, FGG and PGP.	1.37817e-22
NZ_CP023435.1\|WP_071942489.1\|4441218_4441980_+\|CoA-transferase-subunit-A	gnl\|CDD\|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	1.00403e-98
NZ_CP023435.1\|WP_096312971.1\|4456742_4458602_+\|CocE/NonD-family-hydrolase	gnl\|CDD\|273375	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c., putative hydrolase, CocE/NonD family. This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases. [Unknown function, Enzymes of unknown specificity].	3.92766e-128
NZ_CP023435.1\|WP_071942493.1\|4438610_4440188_-\|methylmalonyl-CoA-mutase	gnl\|CDD\|239652	cd03680, MM_CoA_mutase_ICM_like, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM from S. cinnamonensis is comprised of a large and a small subunit. The holoenzyme appears to be an alpha2beta2 heterotetramer with up to 2 molecules of coenzyme B12 bound. The small subunit binds coenzyme B12. ICM catalyzes the reversible rearrangement of n-butyryl-CoA to isobutyryl-CoA, intermediates in fatty acid and valine catabolism, which in S. cinnamonensis can be converted to methylmalonyl-CoA and used in polyketide synthesis.	0

>NZ_CP023435.1|WP_164520226.1|4446005_4446509_+|hypothetical-protein
MDDTTSTTHRPNRQTRSSLGWVAPLALVVALIATGLAGWALLRPAPSTPAPAPAAAPQNGDPKANACAAYRTVSSAVSLQTHADTGAEVQGVAANARLAMSGGATYLLAHLSPATPSDLADAIRAFAAGLQDISMNALAGVPNDDPNQAERLSNAEKTNSKIAELCK
>NZ_CP023435.1|WP_099973839.1|4445642_4445906_-|hypothetical-protein
MTTHWGRRIVYAVGAAGLIVGIAVGAPAAAAQGCPAGHINNQYTGQCYLEGSAPTINGVPCVASNLGLCQSFRQNQQPPRKPYTAIG
>NZ_CP023435.1|WP_071942479.1|4444863_4445646_+|SDR-family-oxidoreductase
MSTPSVFITGAAAGIGRATALTFARNGYRVGAYDIDLDGLAGLREEIVALGGDVVIGELNVTDADQWSARLREFTGSTGTLDILVNNAGVLTTGAFADVPLDVHRQMVDINVYGALAGLHAAFPYLRDTPRAQVVNMCSASAMYGQPELATYSATKFALRALTEALELEWRQYGIRVLALWPLFVKTAMTDGVETASTKSLGVNLQPEDVAAAVYSVTHRRGRLARVHYPVGRQTAVLAALSQVSPNWMQRLMTKTLTRN
>NZ_CP023435.1|WP_071942481.1|4444601_4444862_+|hypothetical-protein
MIKLELPYVTVTVDDRFRNRLAGVGDRLRIRLTAYLRNAADDLDGLGRKATAACQTAAVRVDTAMAAANDRIASEPEVHVAHLKVV
>NZ_CP023435.1|WP_071942483.1|4442996_4444481_+|aldehyde-dehydrogenase-family-protein
MTNVDADTGVLAGEQRMLIDGELRFTDSGALFDVEHPASEQVVGQATDGTVIDVERATAAARRAFDTTDWSRDLEFRYHCLTQLHEALTEEQERLRRIVITEVGCPVSVSGSQIESPIAEVKHWAEHGRNFDYLVDTGIHETQLGPARRKIQFDPVGVVGAITPWNVPFYLNIAETVPALMAGNTVVLKPAQLTPSSGTELGRIIAEKTDIPAGVFNVVTSNANEVGAALSADPRVDMITFTGSTATGRAILTAGASTVKKTLLELGGKSTHIVCDDADFNACLPMAAMFACVMSGQSCILSSRVLLPRSRYDEGLEILKTMMEQFPVGDPWTPGIMQGPQISAMQRQKTLSLIQSGIADGARLVTGGGIPENLPTGYYVQPTLLADVDPTSEIAQTEIFGPVITVTPYDTDDEAVEISNNTIYGLSGDVTSGDDERALNIALRLRTGSVTTNGHSFFGITSPFGGTKQSGLGHRNGDEGYREYLNMKTIGVRP
>NZ_CP023435.1|WP_071942485.1|4442637_4442922_-|DUF1330-domain-containing-protein
MAKGYVILTEDIKDPEGMKAYGKAAGAAMGGVKVLAVDTKPQVLEGNWHGHQTVVLEFESVEAAQAWYDSDAYRAARELRHAAADTNAVILSGF
>NZ_CP023435.1|WP_071942487.1|4441979_4442636_+|CoA-transferase-subunit-B
MTQAATGWTRDQMAARAAAEMIDGEYVNLGIGLPTLIPNYLSSDVRVTLHSENGILGTGPYPTDDAVDADLINAGKETVTVLPGAAFFDSALSFGMIRGGHIDTAVLGGMEVSQTGDLANWMVPGKMVKGMGGAMDLVHGAARVIVLMEHTDRGGNPKIVKQCSLPLTGVGVVDRIITNLGVIDVVGDGTLVLRELAPGVSTDDIVAATEPELTVELS
>NZ_CP023435.1|WP_071942489.1|4441218_4441980_+|CoA-transferase-subunit-A
MTSKVYESAASAVADIPSGATLAVGGFGLCGIPDRLIQALLDAGVTDLEVFSNNCGVDDYGLGILLSDGRIRRITASYVGENKEFARQYLAGELEVELTPQGTLAERLRAGGAGIPAFYTPAGVGSVVSDGGLPWRYAADGSVAIASPPKETRVFGDKRYVLEESINADFALVHAKRGDAYGNLVFNRSAMNFNPLCAMAGRIAIAQVEELVEPGELDPATVHLPGVFINRIVHTGPQDKRIEKRTVRSEEAN
>NZ_CP023435.1|WP_071942491.1|4440285_4441041_-|IclR-family-transcriptional-regulator
MTDRNVVARVAALLGAVGAAEPKGASTTDLGRATELARPTAHRLLTSLAEVGLIDRDAKTGRWLLGPEMYLLGAVAATRYDVTDKAREVVTRLAAETGESAFFSARRGDETVCLLSVEGSFPLRSHVLREGIRFPLGVASAGLAILSHLPADEVDDYFARSLPATAWGDDHTEESIRARIEATRLTGYAVNPALIVEGSWGIAAAVFDRNGRPAWALSLTGVETRFRPDRRHELGTLLLEAAHVLSGRLGS
>NZ_CP023435.1|WP_071942493.1|4438610_4440188_-|methylmalonyl-CoA-mutase
MDHLSHTSSGIPLEPVYGPADRSGDPPAPGTFPFTRGNFSSGYRGRLWTFRQYSGFGTAEESNERYRYLLEQGGTGLSVALDLPTQCGYDSDDPEYGEEVGRVGVAVDTLADAEILFDSIPLDKISTSFTINGTAAILLAFYVAAAEKKGVPREKLTGTIQNDILKEYASRGTWIWPPEPSLRLIADTIEFCAAEVPRFNAISVAGAHFRDAGANAVQEMAFTLADGVTYCDTVVERGRMTIDQFAPQISFFFYTHGDFFEEIAKYRAGRRRWATIVRERWGAKTDKAAMFRFGCVSGGASLYAPQAQNNLVRVAYEALASVLGGVQSMFTAAWDEPFALPSEESATLALRTQQILAYETGVARVADPLGGSYFVEALTDATEERIIEIMSDLEKHGGMVQSIEDGYLQGLIADEAYKIHQEVESGERPVVGVNKFVVDEPAPDLATYELDAEGRDKQLRRLAKVKAERDDVAVKEALAALARSAEGDDNLMHKLIDCANAYCTVGEMVSTLKSVWGEFQQPVVF
>NZ_CP023435.1|WP_071942471.1|4448241_4448775_-|hypothetical-protein
MLLVSGSALFAAPVAFADPDTQQPVPVPGPAPANVAAPVAPLDVPPPDAAPSSAIPDACKQFGGALDYAASYYEDFAYDSAGNGNSVNYQDPNVANSNAIGRTALREAASAAMSAASTPGLPADISAPMRSWSLRAAKLLLIMGIRGGGDSLNSTADDMNTDAKNAQMACAMNGARA
>NZ_CP023435.1|WP_071949661.1|4449200_4449884_+|MspA-family-porin
MLKRFAALAGVCLLAPMGAAPLALADPPADPNAAPAANVGPQGPVPSAAPGVLKTPDGWTLSVTGKDESMEPVASLTNSPWSREYLVDGTFTATVNGGGSTKLAGGTLEAGYQIGCGITQDDIESIATAGATPGVGIPLVNGSLLPITLGLSASYQMKIDLKPGTVNIVPVGKKEFKGTAPRVSITGFRIKIDGCAGQSFIRSYATLTSSTDNTDDVVTYLGVTKAV
>NZ_CP023435.1|WP_071942469.1|4450092_4450779_+|MspA-family-porin
MLHRFATAAAVCMLIPMGATPLALADPADPAAPPVVDAGAPPPPPDNGAVASSVPGIAKTPDGRTLTVVAKDETQLPVAPLTTSLSSRDWVVGATFTGTTTGSVSGGTLETGYQIGCGVEMDKVKLIGSVGASLGNASLGTGGLALPGTISFPVQGQIEVDPRPGTITNVVVDKKKFKGTSSRVTIKDVHIKIDNCVGASSLRSYAVLTSSGTDADDIVAYYGVTKVF
>NZ_CP023435.1|WP_125477477.1|4450802_4451405_+|hypothetical-protein
MLVKGAVVAALTLGAAVAPMATAAADEPLPVDPAAPAPPPPPQGLIPSPATITDSVSGFANYMGGPAGNQLLLGQTPTPALAGTAPATPPNADILNGAQLLMAQNNSMPTPDQTSPYQLGPGADGPFARVNQWKGVHAFLHGALGRMPADQLGQPLPGTAPAPGITIPAGPEQFLPDPAAPPPPGAPGDPALPPPPPPIP
>NZ_CP023435.1|WP_071942465.1|4451491_4452085_+|hypothetical-protein
MSMGDRTLASTLLLAAAVAAALLGSPCATADPAPGDPPQPPPALVPPNATVGSVLAQSDAPAAGPLGLPDLAAYAPGLLLGQNPVPSPPGAANTVATPDLHAFNNQYLVPQNIAPAAPGQGEPDIGIGPTAEQPGTGRLAFLHRLHAMYSEGALDGALLGQVPYEQLGEPLPGTAPAPGVIVPPGLGFGLADPAPAP
>NZ_CP023435.1|WP_071942463.1|4452175_4453165_+|cardiolipin-synthase
MPANAPRVIVEPDDGLDPVLEFIMSAQTSLLIKQFTFTEPSLIDAVIDRKKAGVDVRIMLNPQRSGGDRANDESYETFKTAGIDVQWSSPKFYVTHEKSIVVDESAAMVATYNLMIKYFTLTRDYGIITHDPQHVAQIVEVFNADWEHRDFTPPRYEGLLWSNSNSRYHMARFIDSAERKLYIQHPKYVDAVILDHIAAAAHRGVRVRVLCGGKHGISEWDILDTFASLRTLRRFGVEVRKQKNLRVHAKLLIIDGREVLVGSMNIDRSAFDLRRELGVTTDDPDVVARLKEVFKSDWQISSHYEPPDPLEKNRPVEDEFPHDHDLVHE
>NZ_CP023435.1|WP_071942461.1|4453157_4453733_+|chromate-transporter
MSESGSTREKVSLFEVARTFNHIALASFGGGLGAWSREVIVVEKQWLGEEEFLSAMTMCRIVPGANQVNLAVFVGTKMKGLAGAIAAVIGLCLMPVAIVLTLGFVYFTFKEVPAVKGALHGASAAAVALTLAMVIQTGQKCLKGLMPIAFFLASFVLNGLLRWPLLLTLAILAPLSLIWAWPRKAPEPVDA
>NZ_CP023435.1|WP_071942459.1|4453729_4454275_+|chromate-transporter
MKTFLALIGMFGSLSLLSIGGGNTVLPDMHLQAVTGHHWLTNSQFADIFSISQAAPGPSILIVALVGYAAGLGVFGVVGGIIGGVLATIAMVVPAAGLMYLITVSWQKAQKSKLRYAVEKGFAPLTVGLILASSLVMSKAADHDWRAYLITGVATLIFVRTKTNPLVVVGAAALLGYVGFV
>NZ_CP023435.1|WP_071942457.1|4454320_4456693_+|flippase-like-domain-containing-protein
MRVDGRDVAVSGDVLLPLTRRTNDIVRLSVATVVLVIVVTSSLITRNDWVGLEKSVSRIVGVLTPTQSNLVYLAYGVAILALPFVILIGLIGARQWKLFAAYVAAGFLAVFSLSITGNGIAAPRWHFDLSERLSTTLSQFLDDPRWIAMLAAVLTVSGPWLPGRWRRWWWTLLLAFVPIHLVVSAVIPARSLLGLSVGWFVGALTVWVVGTPALEVPLDGTVRALARRGFLVTSLTVVRPAGSGPLELAAADDAGVRMVLEMYGPNQRSGGALRQFWRWLILRDAETAPLQASMRRAVEHRALMTIAVSDLGVSNTTTMVVAALERGWTLYAHTPPLGDPIGDACDETLVTAVWGAFGVLHRHQIAHGGLRFKEMTVDAGRVMFGGFGNSEYGATDEQLQSDIAALLVTTSDRFGPESAVQAAVHTLGKETVLNASRRLTRAAVPARIRKSVNDPKAVMAAARDEVKRQTGADEIKTETITRFTRKQVIQLVLLVALVYVAYPFISTVPTFFSELRNANWWWALLGLAVSAMTYVGAAAALWACASGLVSFGNLVIMQFANTFAATTTPAGVGGLALSTRFLQKGGLGALRATAAVALQQAVQVITHVSLLILFSVAAGATADLSHFVPSTTLLYLIGGVALGILGTFLLVPKARRWLGTAVRPRLQEVGHELLELMREPKRLAVIVLGCATTTLGMALVLWSSIEAFGGDTTFVTVTIVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAAVGVPAVLLYRVLTCWVPVFAGWPIMRWLTAKEMI
>NZ_CP023435.1|WP_096312971.1|4456742_4458602_+|CocE/NonD-family-hydrolase
MTLALALVLSACAGPGRHGTDSAWPPSSGRGPCGVSKQTDVPARMRDGTVLRADVYRPDTSDPVPVILMRTQYGKSGAQVQPSRYQSPDWFASHCYLVVIQDVRGQGASAGTFSEFTHDRDDGYDSVEWAAALPGSNGKVGMYGSSYVGATQWLAATATPPHLVTIVPANTASDYYDGWMYEGGEFRLAFVQPWAIGLATTAAENRHDGTTAAALKAAAADSTRWLDFLPYRALPPMQPANPAVAPWYFDWIAHSTRDDFWRQWSIRDRYPSVRVPVLDIEGWYDAFLAGGIENFTGMVNSAGTSEGRRNQRLVIGPWDHVDWGRPGSEPAPSLKDIGPVGETPINELMLAWYDHFLKGVDNHVSGKPRVDYFLMGANRWKSADSWPLPNTQWSRYFLSGDGQIDSRTGTLSTAAPGTSQAPDHYVYDPTDPAPSVGGHSCCGAKSGPQGPYDQIPVEQRSDVLVYTSDPLSSDTEVTGPTTVDLWASSSAIDTDFTAKLIVVKPDGDAINLNNGILRTSFRDSLSDPRPGVPDQPYEYHIAIWPTSYLFRTGDRIRLEISSSDYPQFAPNPNTGDRFGQSAATLPATQTILHDAAHPSAVVIPVVPAGGPESDHVPMR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP023435_1	1.6\|4447279\|20\|NZ_CP023435\|CRISPRCasFinder	4447279-4447298	20	NZ_CP023435.1	4447585-4447604	2	0.9

1. spacer 1.6|4447279|20|NZ_CP023435|CRISPRCasFinder matches to position: 4447585-4447604, mismatch: 2, identity: 0.9

gccggcggtaacggcggaaa	CRISPR spacer
gccggcgggaacggcggtaa	Protospacer
******** ******** **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NZ_CP054046	Yersinia massiliensis strain 2011N-4075 plasmid unnamed1, complete sequence	30566-30594	4	0.862
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	597768-597796	5	0.828
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NC_011273	Mycobacterium phage Myrna, complete genome	63646-63674	5	0.828
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	MG944220	Mycobacterium phage Ruotula, complete genome	29197-29225	6	0.793
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NZ_CP048608	Pseudomonas fluorescens strain DR133 plasmid unnamed, complete sequence	80350-80378	6	0.793
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	MT074482	Salmonella phage horsemountain, partial genome	21405-21433	6	0.793
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	MN428063	Gordonia phage NadineRae, complete genome	14470-14498	6	0.793
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	MH271305	Gordonia phage Morrissey, complete genome	3375-3403	6	0.793
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NC_008759	Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence	110219-110247	6	0.793
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	MN813686	Mycobacterium phage BirdsNest, complete genome	31887-31915	7	0.759
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	MT498037	Streptomyces phage Dryad, complete genome	26314-26342	7	0.759
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NC_015952	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence	23257-23285	7	0.759
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NC_031279	Mycobacterium phage Bactobuster, complete genome	5428-5456	8	0.724
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	KY555144	Caulobacter phage Ccr5, complete genome	37883-37911	8	0.724
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	NZ_KT935446	Klebsiella pneumoniae strain Kp2964 plasmid 2964TF, complete sequence	88633-88661	8	0.724
NZ_CP023435_1	1.3\|4447078\|29\|NZ_CP023435\|CRISPRCasFinder	4447078-4447106	29	KX610764	Mycobacterium phage Kersh, complete genome	52482-52510	9	0.69

1. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NZ_CP054046 (Yersinia massiliensis strain 2011N-4075 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.862

-ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
cggtga-ggcaacaacggcggcaaccgtgg	Protospacer
 ***.* *** ************** ****

2. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.828

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
accaacggctacaacgccggcaccggtgg	Protospacer
. .************* ***** ******

3. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NC_011273 (Mycobacterium phage Myrna, complete genome) position: , mismatch: 5, identity: 0.828

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
accaacgtctacaacggcggcaacggcgg	Protospacer
. .**** ******************.**

4. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to MG944220 (Mycobacterium phage Ruotula, complete genome) position: , mismatch: 6, identity: 0.793

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
atccccggctccaacggcggcaacggtgg	Protospacer
. .  ***** ******************

5. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NZ_CP048608 (Pseudomonas fluorescens strain DR133 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
ctcaacggctacaacggcgccgacggtga	Protospacer
  .**************** *.******.

6. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to MT074482 (Salmonella phage horsemountain, partial genome) position: , mismatch: 6, identity: 0.793

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
tgtagcggctacaacggcggcaagaccgg	Protospacer
 ***.****************** . .**

7. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to MN428063 (Gordonia phage NadineRae, complete genome) position: , mismatch: 6, identity: 0.793

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
gacaacggcgacaacggcgacaacgggga	Protospacer
*..****** *********.****** *.

8. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to MH271305 (Gordonia phage Morrissey, complete genome) position: , mismatch: 6, identity: 0.793

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
gacaacggcgacaacggcgacaacggcga	Protospacer
*..****** *********.******.*.

9. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NC_008759 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence) position: , mismatch: 6, identity: 0.793

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
ggcaacggctacagcggcggcaatcacgg	Protospacer
**.**********.*********. ..**

10. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to MN813686 (Mycobacterium phage BirdsNest, complete genome) position: , mismatch: 7, identity: 0.759

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
tcgagcgcctacaacggcggcaacggcgc	Protospacer
   *.** ******************.*

11. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to MT498037 (Streptomyces phage Dryad, complete genome) position: , mismatch: 7, identity: 0.759

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
gagaacggctacaacgacggcaacatggt	Protospacer
*. *************.*******.  *

12. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NC_015952 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence) position: , mismatch: 7, identity: 0.759

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
aggcgcggcaacaacggcggcaacggcga	Protospacer
.*  .**** ****************.*.

13. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NC_031279 (Mycobacterium phage Bactobuster, complete genome) position: , mismatch: 8, identity: 0.724

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
atcaacggcaacaacggcggcaacaccgt	Protospacer
. .****** **************. .*

14. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to KY555144 (Caulobacter phage Ccr5, complete genome) position: , mismatch: 8, identity: 0.724

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
accggcctctacaacggcggcaacggcgg	Protospacer
. ...*  ******************.**

15. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to NZ_KT935446 (Klebsiella pneumoniae strain Kp2964 plasmid 2964TF, complete sequence) position: , mismatch: 8, identity: 0.724

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
aactacggctacaacgccgccaacggtca	Protospacer
... ************ ** ******* .

16. spacer 1.3|4447078|29|NZ_CP023435|CRISPRCasFinder matches to KX610764 (Mycobacterium phage Kersh, complete genome) position: , mismatch: 9, identity: 0.69

ggtaacggctacaacggcggcaacggtgg	CRISPR spacer
cccctcggctacaaccgcggcaacgggca	Protospacer
  .  ********** **********  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1420812 : 1476295

Burkholderia_virus(25.0%)

tRNA,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071947173.1\|1420812_1421829_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_071947172.1\|1421849_1422887_+	inner membrane protein YhjD	NA	NA	NA	NA
WP_096310501.1\|1423988_1425247_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.6e-84	59.6
WP_071947171.1\|1425744_1426980_-	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	2.9e-07	28.9
WP_071950040.1\|1427047_1428046_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_071947170.1\|1428036_1429416_-	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_174714109.1\|1429412_1429934_-	AsnC family transcriptional regulator	NA	NA	NA	NA
WP_096310503.1\|1430050_1431553_+	gamma-aminobutyraldehyde dehydrogenase	NA	NA	NA	NA
WP_096310505.1\|1431553_1433083_+	gamma-glutamyltransferase	NA	NA	NA	NA
WP_096310508.1\|1433079_1434822_-	APC family permease	NA	NA	NA	NA
WP_071947166.1\|1434943_1435522_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_096310510.1\|1435615_1436794_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_096310512.1\|1436795_1437902_+	acyl-CoA/acyl-ACP dehydrogenase	NA	NA	NA	NA
WP_083542942.1\|1437910_1438396_+	MaoC family dehydratase N-terminal domain-containing protein	NA	NA	NA	NA
WP_096310514.1\|1438392_1438830_+	MaoC family dehydratase	NA	NA	NA	NA
WP_096312738.1\|1438826_1440029_+	thiolase family protein	NA	NA	NA	NA
WP_096310516.1\|1440028_1440436_+	OB-fold domain-containing protein	NA	NA	NA	NA
WP_096310518.1\|1440432_1442025_+	AMP-binding protein	A0A1V0SBX8	Catovirus	1.7e-07	24.6
WP_071947158.1\|1441996_1442767_-	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_071947157.1\|1442766_1444521_-	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_071947156.1\|1444539_1445001_-	succinate dehydrogenase hydrophobic membrane anchor subunit	NA	NA	NA	NA
WP_071947155.1\|1444997_1445420_-	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
WP_071947154.1\|1445600_1446014_+	cytidine deaminase	NA	NA	NA	NA
WP_071947153.1\|1446010_1447297_+	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	3.2e-81	42.5
WP_096310520.1\|1447293_1448382_+	adenosine deaminase	NA	NA	NA	NA
WP_096310522.1\|1448360_1448696_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_096310524.1\|1448787_1450812_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.1e-92	36.3
WP_096310526.1\|1450821_1453968_+	RND family transporter	NA	NA	NA	NA
WP_096310528.1\|1453968_1455231_-	primosomal protein	NA	NA	NA	NA
WP_096310530.1\|1455275_1455848_+	YdcF family protein	NA	NA	NA	NA
WP_071947146.1\|1455869_1456493_+	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_071947145.1\|1456493_1458086_-	phospho-sugar mutase	NA	NA	NA	NA
WP_071947144.1\|1458082_1458517_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_071947143.1\|1458603_1459716_+	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_096312740.1\|1459634_1460426_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_096310532.1\|1460457_1461645_+	M20 family metallopeptidase	NA	NA	NA	NA
WP_071947140.1\|1461641_1462811_+	amidohydrolase	NA	NA	NA	NA
WP_071947139.1\|1462810_1463770_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	3.9e-44	34.4
WP_071947138.1\|1463766_1464249_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_071950038.1\|1464349_1465765_+	NAD(P)H-quinone dehydrogenase	NA	NA	NA	NA
WP_096310534.1\|1465774_1467520_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_096310536.1\|1467516_1468389_+	pseudouridine synthase	NA	NA	NA	NA
WP_071947135.1\|1468421_1468979_+	DUF1269 domain-containing protein	NA	NA	NA	NA
WP_096310538.1\|1468947_1469715_-	Fpg/Nei family DNA glycosylase	NA	NA	NA	NA
WP_096310540.1\|1470125_1470416_+\|transposase	transposase	NA	NA	NA	NA
WP_096310542.1\|1470412_1471345_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.3e-32	31.5
WP_096310544.1\|1472452_1473714_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	9.3e-70	53.3
WP_096312741.1\|1473662_1473944_+\|transposase	transposase	NA	NA	NA	NA
WP_071948729.1\|1475215_1476295_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

1866865 : 1874550

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096310896.1\|1866865_1867732_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	2.9e-06	30.1
WP_096312767.1\|1867728_1868772_-	DNA polymerase IV	F1C5A5	Cronobacter_phage	6.4e-16	26.2
WP_164520042.1\|1868768_1869377_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_096310897.1\|1869459_1870002_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	3.3e-08	35.7
WP_096310898.1\|1870055_1870886_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_071946603.1\|1871664_1871904_+	redoxin NrdH	V5UN81	Mycobacterium_phage	2.2e-20	64.4
WP_096310899.1\|1871932_1872415_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A217ER62	Bacillus_phage	2.8e-06	27.9
WP_174714112.1\|1872432_1874550_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	3.6e-207	51.0

DBSCAN-SWA_3

2440535 : 2447605

Mycobacterium_phage(57.14%)

integrase,protease

attL 2435207:2435229|attR 2452178:2452200

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2435207:2435229	attL	NA	NA	NA	NA
WP_096312820.1\|2440535_2441756_+\|integrase	site-specific integrase	A0A1D8EV90	Mycobacterium_phage	9.1e-54	34.8
WP_096311234.1\|2441755_2442214_+	hypothetical protein	NA	NA	NA	NA
WP_096311235.1\|2442311_2442515_+	excisionase family DNA-binding protein	A0A2P1CHK7	Mycobacterium_phage	4.5e-19	82.5
WP_096311236.1\|2442651_2443134_+	hypothetical protein	NA	NA	NA	NA
WP_164520060.1\|2443243_2444182_+	AAA family ATPase	A0A2D1GDF8	Mycobacterium_phage	3.7e-71	46.3
WP_164520061.1\|2444432_2444606_+	hypothetical protein	NA	NA	NA	NA
WP_096311238.1\|2444595_2444853_+	hypothetical protein	NA	NA	NA	NA
WP_096311239.1\|2444849_2445242_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_174714180.1\|2445322_2445838_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A142K8P6	Gordonia_phage	8.3e-41	64.2
WP_096311241.1\|2445839_2446223_+	DUF2190 family protein	A0A142K9Z3	Gordonia_phage	1.1e-26	59.5
WP_096311242.1\|2446234_2447116_+	hypothetical protein	A0A2K9VEV5	Mycobacterium_phage	2.4e-56	38.5
WP_096311243.1\|2447128_2447605_+	hypothetical protein	A0A1B3AZ47	Gordonia_phage	2.5e-07	34.1
2452178:2452200	attR	NA	NA	NA	NA

DBSCAN-SWA_4

2514190 : 2523422

uncultured_Mediterranean_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096311271.1\|2514190_2515453_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.4e-20	27.8
WP_096311272.1\|2515459_2517112_+	hypothetical protein	NA	NA	NA	NA
WP_083542643.1\|2517108_2517636_+	adenine phosphoribosyltransferase	A0A2K9L0U5	Tupanvirus	4.7e-07	27.3
WP_096311273.1\|2517726_2520078_+	RelA/SpoT family protein	A0A2I2L310	Orpheovirus	8.8e-13	37.9
WP_164520063.1\|2520091_2520376_-	hypothetical protein	NA	NA	NA	NA
WP_096311274.1\|2520501_2520744_+	hypothetical protein	NA	NA	NA	NA
WP_096311275.1\|2520755_2521751_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.2e-08	32.7
WP_096311276.1\|2521757_2522645_-	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	1.3e-06	31.1
WP_096311277.1\|2522753_2523422_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.8e-19	32.0

DBSCAN-SWA_5

3407688 : 3416184

Staphylococcus_phage(33.33%)

transposase,integrase

attL 3399324:3399339|attR 3419720:3419735

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3399324:3399339	attL	NA	NA	NA	NA
WP_071944019.1\|3407688_3409242_-\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	1.5e-16	27.1
WP_164520088.1\|3409693_3410440_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_125477522.1\|3411681_3412881_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.3e-32	34.8
WP_174714194.1\|3413215_3413779_+\|transposase	transposase	A0A1B3AZF8	Gordonia_phage	3.7e-18	52.5
WP_096311611.1\|3413775_3414570_+\|transposase	IS3 family transposase	A0A1B3AZE5	Gordonia_phage	2.6e-41	46.9
WP_125477522.1\|3414659_3415859_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.3e-32	34.8
WP_164520089.1\|3415842_3416184_+\|transposase	transposase	Q8W6R2	Burkholderia_virus	5.3e-28	62.8
3419720:3419735	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3961037 : 4023506

Streptomyces_phage(16.67%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_174714091.1\|3961037_3961466_+\|transposase	IS3 family transposase	A0A2P1JR32	Mycobacterium_phage	2.5e-27	50.4
WP_096310927.1\|3961527_3962665_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.3e-33	34.4
WP_096311543.1\|3963327_3964487_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-34	35.4
WP_096311544.1\|3964744_3966005_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	3.0e-84	60.1
WP_125477458.1\|3966230_3966836_+	hypothetical protein	NA	NA	NA	NA
WP_096311810.1\|3966914_3968015_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-54	37.9
WP_071943109.1\|3968011_3969460_-	GTPase ObgE	NA	NA	NA	NA
WP_096311811.1\|3969541_3969802_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_071943105.1\|3969816_3970140_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_096311812.1\|3970298_3973205_-	ribonuclease E/G	NA	NA	NA	NA
WP_096311813.1\|3973488_3973899_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.1e-27	50.0
WP_096311814.1\|3973916_3974315_-	DUF4233 domain-containing protein	NA	NA	NA	NA
WP_096311815.1\|3974311_3975718_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_096311816.1\|3975714_3978366_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.6e-140	38.9
WP_096311817.1\|3978392_3979652_-	saccharopine dehydrogenase NADP-binding domain-containing protein	NA	NA	NA	NA
WP_096311818.1\|3979675_3981661_-	S9 family peptidase	NA	NA	NA	NA
WP_096311819.1\|3981697_3982864_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_071943091.1\|3982889_3983381_-	transglycosylase family protein	A0A1J0GVU2	Streptomyces_phage	1.4e-26	59.5
WP_174714135.1\|3983561_3983969_-	transglycosylase family protein	A0A1J0GVU2	Streptomyces_phage	2.6e-29	69.1
WP_096311820.1\|3984529_3985765_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.5e-109	49.9
WP_096311821.1\|3986088_3986667_-	molybdenum cofactor guanylyltransferase	NA	NA	NA	NA
WP_071943087.1\|3986685_3987762_-	2-oxoacid:ferredoxin oxidoreductase subunit beta	NA	NA	NA	NA
WP_071943085.1\|3987758_3989705_-	2-oxoacid:acceptor oxidoreductase subunit alpha	NA	NA	NA	NA
WP_096311822.1\|3989986_3990835_-	carbohydrate kinase	NA	NA	NA	NA
WP_096311823.1\|3990936_3991941_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_096311824.1\|3992022_3993183_+	phytanoyl-CoA dioxygenase family protein	NA	NA	NA	NA
WP_096311825.1\|3993179_3994184_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_096311826.1\|3994180_3995053_+	TIM barrel protein	NA	NA	NA	NA
WP_096311827.1\|3995049_3996027_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_071943072.1\|3996573_3997389_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.7e-12	27.4
WP_071943070.1\|3997396_3998455_-	ABC transporter permease	NA	NA	NA	NA
WP_096311828.1\|3998474_3999464_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_096311829.1\|3999583_4000357_+	TIM barrel protein	NA	NA	NA	NA
WP_096311830.1\|4000358_4001114_-	dihydrofolate reductase family protein	NA	NA	NA	NA
WP_096312934.1\|4001110_4002478_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_071949701.1\|4002724_4003456_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_071943060.1\|4003609_4004581_+	5-dehydro-2-deoxygluconokinase	NA	NA	NA	NA
WP_071943058.1\|4004573_4005452_+	aldolase	NA	NA	NA	NA
WP_096311831.1\|4005455_4006331_+	5-deoxy-glucuronate isomerase	NA	NA	NA	NA
WP_096311832.1\|4006333_4008283_+	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing)	NA	NA	NA	NA
WP_096311833.1\|4008295_4009213_+	TIM barrel protein	NA	NA	NA	NA
WP_096312935.1\|4009230_4010250_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_096311834.1\|4010251_4011127_+	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_071949700.1\|4011135_4012626_+	CoA-acylating methylmalonate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_096311835.1\|4012675_4013395_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_096311836.1\|4013366_4013945_-	dihydrofolate reductase family protein	NA	NA	NA	NA
WP_096311837.1\|4014013_4014694_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_096311838.1\|4014757_4016932_-	glutamine synthetase III	NA	NA	NA	NA
WP_096311839.1\|4017129_4018554_+	HNH endonuclease	NA	NA	NA	NA
WP_096311840.1\|4018991_4021334_+	FdhF/YdeP family oxidoreductase	NA	NA	NA	NA
WP_071943038.1\|4021321_4022149_+	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_071943036.1\|4022225_4023506_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.2e-141	59.5

DBSCAN-SWA_7

4306015 : 4365780

Corynebacterium_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071942689.1\|4306015_4307419_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_071942680.1\|4307955_4309191_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.4e-110	50.1
WP_125477522.1\|4310976_4312176_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.3e-32	34.8
WP_071949674.1\|4313633_4314104_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_096312005.1\|4314244_4315177_-	lipoyl synthase	NA	NA	NA	NA
WP_071942677.1\|4315300_4315591_-	hypothetical protein	NA	NA	NA	NA
WP_083542881.1\|4315773_4316970_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_071949673.1\|4316984_4319321_-	pyruvate dehydrogenase	NA	NA	NA	NA
WP_071942673.1\|4319639_4320842_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_071949672.1\|4320952_4324450_+	indolepyruvate ferredoxin oxidoreductase family protein	NA	NA	NA	NA
WP_071942671.1\|4325165_4325852_-	hypothetical protein	NA	NA	NA	NA
WP_071942669.1\|4325911_4326214_-	toxin	NA	NA	NA	NA
WP_096312006.1\|4326210_4326438_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_174714139.1\|4326924_4328220_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_096312963.1\|4328814_4329807_+	hypothetical protein	NA	NA	NA	NA
WP_096312007.1\|4329799_4330288_+	DNA-binding protein	NA	NA	NA	NA
WP_096312964.1\|4330299_4330578_-	hypothetical protein	NA	NA	NA	NA
WP_096312965.1\|4330717_4331023_+	hypothetical protein	NA	NA	NA	NA
WP_096312008.1\|4331019_4331331_+	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_096312009.1\|4331466_4332870_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_125477475.1\|4333101_4333485_-	hypothetical protein	NA	NA	NA	NA
WP_125477476.1\|4333593_4333851_-	hypothetical protein	NA	NA	NA	NA
WP_071942658.1\|4333859_4334918_-	hypothetical protein	NA	NA	NA	NA
WP_071942656.1\|4334948_4336787_-	hypothetical protein	NA	NA	NA	NA
WP_096312012.1\|4336817_4336997_-	hypothetical protein	NA	NA	NA	NA
WP_174714202.1\|4337351_4338146_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_071942689.1\|4338546_4339950_+\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_083542563.1\|4340113_4341382_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_071942651.1\|4341497_4341959_+	hypothetical protein	NA	NA	NA	NA
WP_083542562.1\|4341961_4343491_+	cytosine permease	NA	NA	NA	NA
WP_071942649.1\|4343487_4344870_+	hypothetical protein	NA	NA	NA	NA
WP_071942647.1\|4344866_4345118_+	ferredoxin	NA	NA	NA	NA
WP_096312014.1\|4345167_4345488_+	hypothetical protein	NA	NA	NA	NA
WP_071942645.1\|4345484_4346528_+	NAD(P)-dependent alcohol dehydrogenase	NA	NA	NA	NA
WP_083542560.1\|4346517_4349472_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_071942643.1\|4349496_4349829_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_071949669.1\|4352543_4354073_-	AMP-binding protein	A0A1V0SBX8	Catovirus	1.1e-19	25.1
WP_071942641.1\|4354146_4354863_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_071942639.1\|4354872_4356081_-	hypothetical protein	NA	NA	NA	NA
WP_071942637.1\|4356067_4356901_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_071942635.1\|4356908_4358078_-	sulfotransferase	NA	NA	NA	NA
WP_071942633.1\|4358074_4359202_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_096312015.1\|4359201_4360020_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_096312016.1\|4360047_4360692_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_096312017.1\|4360774_4361275_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_096312018.1\|4361274_4362390_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_096312019.1\|4362386_4363172_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_096312020.1\|4363168_4364134_+	phosphotransferase family protein	NA	NA	NA	NA
WP_096311544.1\|4364518_4365780_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	3.0e-84	60.1

DBSCAN-SWA_8

5536913 : 5566476

Bacillus_phage(20.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_125477502.1\|5536913_5538155_-\|protease	PecA family PE domain-processing aspartic protease	NA	NA	NA	NA
WP_125477503.1\|5538189_5538549_+	hypothetical protein	NA	NA	NA	NA
WP_174714216.1\|5538880_5539075_-	PASTA domain-containing protein	NA	NA	NA	NA
WP_071950254.1\|5539224_5540274_-	DNA polymerase domain-containing protein	NA	NA	NA	NA
WP_071948786.1\|5540314_5541379_+	ATP-dependent DNA ligase	NA	NA	NA	NA
WP_071948785.1\|5541375_5541774_-	DUF302 domain-containing protein	NA	NA	NA	NA
WP_047333857.1\|5541797_5542067_-	metal-sensitive transcriptional regulator	NA	NA	NA	NA
WP_071948784.1\|5542293_5543673_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_071948783.1\|5543697_5544471_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_071948782.1\|5544481_5544970_-	bacterioferritin	NA	NA	NA	NA
WP_071948781.1\|5545383_5547942_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.5e-29	25.8
WP_071950253.1\|5547938_5549699_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.8e-24	28.8
WP_071948780.1\|5549733_5550618_+\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
WP_083542810.1\|5550663_5552136_+	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_071948779.1\|5552132_5552909_+	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.8e-22	31.2
WP_071948778.1\|5552938_5554312_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_096312475.1\|5554313_5555534_-	cytochrome P450	NA	NA	NA	NA
WP_174714150.1\|5555633_5556857_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	9.7e-56	34.2
WP_096312476.1\|5556878_5557778_-	haloalkane dehalogenase	NA	NA	NA	NA
WP_071948774.1\|5557962_5558472_+	lipoprotein LpqH	NA	NA	NA	NA
WP_071948773.1\|5558542_5559910_-	wax ester/triacylglycerol synthase family O-acyltransferase	NA	NA	NA	NA
WP_125477504.1\|5559995_5560268_-	hypothetical protein	NA	NA	NA	NA
WP_071948771.1\|5560378_5560786_-	hypothetical protein	NA	NA	NA	NA
WP_164520153.1\|5560841_5561186_-\|transposase	transposase	Q8W6R2	Burkholderia_virus	9.1e-28	68.6
WP_125477506.1\|5561403_5562603_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	6.6e-33	35.1
WP_071948769.1\|5562550_5563222_-\|transposase	IS3 family transposase	A0A1B3AZE5	Gordonia_phage	4.8e-41	46.4
WP_164520154.1\|5563218_5563497_-\|transposase	transposase	A0A1B3AZF8	Gordonia_phage	4.6e-14	56.9
WP_096312477.1\|5564102_5564342_+	hypothetical protein	NA	NA	NA	NA
WP_071947841.1\|5564611_5565847_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	1.4e-81	44.2
WP_125477507.1\|5566164_5566476_+	DNA-binding protein	A0A2P1N3P2	Mycobacterium_phage	4.7e-07	35.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage