CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP010349	Burkholderia mallei strain Turkey10 chromosome 2, complete sequence	3 crisprs	csa3	1	0	5	0
NZ_CP010348	Burkholderia mallei strain Turkey10 chromosome 1, complete sequence	0 crisprs	cas3,DEDDh,DinG,csa3	0	0	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP010349_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010349_1

128743-128835

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGACGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010349_1

>merge|NZ_CP010349|1|128743-128835|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NZ_CP010349|1|1|128743-128835|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010349.1\|WP_053799650.1\|136958_138794_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP010349.1\|WP_004187423.1\|124513_124771_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004187158.1\|133993_134503_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004188537.1\|144372_145899_-\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NZ_CP010349.1\|WP_053799651.1\|129270_131271_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NZ_CP010349.1\|WP_004187193.1\|128275_128524_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NZ_CP010349.1\|WP_044302747.1\|135004_136609_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP010349.1\|WP_004201694.1\|127272_127581_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NZ_CP010349.1\|WP_004198321.1\|132330_133356_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NZ_CP010349.1\|WP_004188303.1\|131267_132116_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NZ_CP010349.1\|WP_004188525.1\|138943_140068_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NZ_CP010349.1\|WP_004188073.1\|124742_126347_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NZ_CP010349.1\|WP_004188840.1\|122588_124382_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NZ_CP010349.1\|WP_004188594.1\|121174_122578_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NZ_CP010349.1\|WP_004187346.1\|127577_128279_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NZ_CP010349.1\|WP_004188458.1\|119999_121178_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NZ_CP010349.1\|WP_004188438.1\|126788_127280_+\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NZ_CP010349.1\|WP_004203331.1\|140070_143310_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP010349.1\|WP_004188221.1\|126336_126792_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NZ_CP010349.1\|WP_004198322.1\|133432_133936_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP010349.1\|WP_004188537.1\|144372_145899_-\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	7.30998e-99
NZ_CP010349.1\|WP_053799650.1\|136958_138794_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.39554e-132
NZ_CP010349.1\|WP_053799651.1\|129270_131271_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NZ_CP010349.1\|WP_004187193.1\|128275_128524_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37
NZ_CP010349.1\|WP_044302747.1\|135004_136609_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.56608e-79
NZ_CP010349.1\|WP_004201694.1\|127272_127581_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.23546e-10
NZ_CP010349.1\|WP_004198321.1\|132330_133356_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP010349.1\|WP_004188303.1\|131267_132116_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	1.10329e-32
NZ_CP010349.1\|WP_004188525.1\|138943_140068_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	6.54035e-26
NZ_CP010349.1\|WP_004188073.1\|124742_126347_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NZ_CP010349.1\|WP_004188840.1\|122588_124382_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NZ_CP010349.1\|WP_004188594.1\|121174_122578_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NZ_CP010349.1\|WP_004187346.1\|127577_128279_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NZ_CP010349.1\|WP_004188458.1\|119999_121178_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NZ_CP010349.1\|WP_004188438.1\|126788_127280_+\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	7.77353e-17
NZ_CP010349.1\|WP_004203331.1\|140070_143310_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.86967e-92
NZ_CP010349.1\|WP_004188221.1\|126336_126792_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63

>NZ_CP010349.1|WP_004187193.1|128275_128524_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NZ_CP010349.1|WP_004187346.1|127577_128279_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NZ_CP010349.1|WP_004201694.1|127272_127581_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQFARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NZ_CP010349.1|WP_004188438.1|126788_127280_+|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRGAARRDPSPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NZ_CP010349.1|WP_004188221.1|126336_126792_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NZ_CP010349.1|WP_004188073.1|124742_126347_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVFVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
>NZ_CP010349.1|WP_004187423.1|124513_124771_-|hypothetical-protein
MPFVACGSATVAPVWLVRRWLHHNGARRPPADLGQETGNRQTKRGIAQSETIDASASGADKVRAASIVDSNQIPQTYAWLQWPCQ
>NZ_CP010349.1|WP_004188840.1|122588_124382_-|alpha/beta-fold-hydrolase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NZ_CP010349.1|WP_004188594.1|121174_122578_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGTRLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NZ_CP010349.1|WP_004188458.1|119999_121178_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHVRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLSVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NZ_CP010349.1|WP_053799651.1|129270_131271_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANVDAEAEARHKR
>NZ_CP010349.1|WP_004188303.1|131267_132116_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGETAAGARAAPRARFVVVLCSEQGFVGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NZ_CP010349.1|WP_004198321.1|132330_133356_+|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGATFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NZ_CP010349.1|WP_004198322.1|133432_133936_+|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NZ_CP010349.1|WP_004187158.1|133993_134503_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAADGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVSTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NZ_CP010349.1|WP_044302747.1|135004_136609_+|methyl-accepting-chemotaxis-protein
MAPFHRRTTRNARTPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NZ_CP010349.1|WP_053799650.1|136958_138794_-|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLVVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>NZ_CP010349.1|WP_004188525.1|138943_140068_-|ABC-transporter-permease
MRRLAIIYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMDAGDFTFALDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NZ_CP010349.1|WP_004203331.1|140070_143310_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQEAQGGAGERPGAGERAAGESVAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVGSDVGSEVASEAGLAASAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHELYSQFWPLAACVPVILGATILLLKKQER
>NZ_CP010349.1|WP_004188537.1|144372_145899_-|efflux-transporter-outer-membrane-subunit
MTMRNDARHDERHQRRRGIARRAARHAAALALCAAVSGCLSLAPDYARKPPPVPAAYPAYPGEPGAGSRTLEQLGWRAYFVDPRLQALIETALANNRDLRIAAQRVEQARAAYGIRRADQYPTIAANAAYLRFREPGGLLLPSPIIGELYSASLSEVQWEIDFWGRVRSLKAAALDTFLASDASRRAVTVSLIGQVADAYLALCAYDERLALTNETIASRRDSLRIFRRRYEEGAISKLDLTQSEILLQQAQTLGSQLQQARDVQQHALDLLVGTNAAARTPASLDDASIAPDLAPGLPSELLANRPDVVAAEYQLRAAHANIGAARAAFFPRIALTSSIGTGSTELHNLFASGTAAWNFIPNLSVPIFDAGRNIGNLKLANARRDEALAQYEKTIQTAFRDVADALAARHWLADQVRIAQETLATQAERARLAKLRYDSGAARFLEVLDAQRDLLNAQQQLVQTRRALLASRVALYAALGGRLDEPARDGAAPRPSPEPSAKQGPLS

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Crispr_ID: NZ_CP010349_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010349_2

1727193-1727340

Orphan

Consensus_repeat	Method
GCACGACAGCACGACAGCACGACAGCAC	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NZ_CP010349_2

>merge|NZ_CP010349|2|1727193-1727340|CRISPRCasFinder
GCACAAATACACGAACACGCGACCGCACGCCCACACGCACACCCGACCACGCAATCGCGCAATCGAGCAATCGAGCAATCGCACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCACGACAGCAC

>NZ_CP010349|2|2|1727193-1727340|CRISPRCasFinder
GCACAAATACACGAACACGCGACCGCAC	GCCCACACGCACACCCGACCACGCAATCGCGCAATCGAGCAATC
GAGCAATCGCACGACAGCACGACAGCAC	GACAGCACGACAGCACGACA
GCACGACAGCACGACAGCACGACAGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010349.1\|WP_004190255.1\|1735082_1737446_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|131764
NZ_CP010349.1\|WP_004190526.1\|1721891_1723133_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP010349.1\|WP_004190404.1\|1731322_1732147_+\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP010349.1\|WP_004190661.1\|1725642_1726977_+\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NZ_CP010349.1\|WP_004553904.1\|1732437_1733841_+\|indoleacetamide-hydrolase	unknown	unknown	gnl\|CDD\|236030
NZ_CP010349.1\|WP_004190962.1\|1718462_1719404_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NZ_CP010349.1\|WP_004190793.1\|1723179_1724301_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP010349.1\|WP_004536572.1\|1719634_1719940_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004190530.1\|1738987_1739278_-\|H-NS-histone-family-protein	unknown	unknown	gnl\|CDD\|376390
NZ_CP010349.1\|WP_004190523.1\|1715977_1716892_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NZ_CP010349.1\|WP_004190791.1\|1715091_1715796_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187602
NZ_CP010349.1\|WP_004266659.1\|1734026_1734578_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_162473499.1\|1737987_1738881_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004190287.1\|1729963_1730812_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP010349.1\|WP_004537687.1\|1720399_1721074_-\|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238089
NZ_CP010349.1\|WP_009950654.1\|1724791_1725190_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_162186992.1\|1730951_1731116_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004190897.1\|1728637_1729780_+\|alpha-hydroxy-acid-oxidizing-protein	unknown	unknown	gnl\|CDD\|376451
NZ_CP010349.1\|WP_004190252.1\|1721146_1721887_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810
NZ_CP010349.1\|WP_004190485.1\|1727649_1728573_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990

Protein	Function_ID	Function_description	E-value
NZ_CP010349.1\|WP_004190255.1\|1735082_1737446_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	1.3724e-91
NZ_CP010349.1\|WP_004190526.1\|1721891_1723133_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.81048e-43
NZ_CP010349.1\|WP_004190404.1\|1731322_1732147_+\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	7.35336e-44
NZ_CP010349.1\|WP_004190661.1\|1725642_1726977_+\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.19386e-146
NZ_CP010349.1\|WP_004553904.1\|1732437_1733841_+\|indoleacetamide-hydrolase	gnl\|CDD\|236030	PRK07488, PRK07488, indoleacetamide hydrolase.	0
NZ_CP010349.1\|WP_004190962.1\|1718462_1719404_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.47871e-74
NZ_CP010349.1\|WP_004190793.1\|1723179_1724301_+\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	1.93787e-167
NZ_CP010349.1\|WP_004190523.1\|1715977_1716892_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	2.45018e-87
NZ_CP010349.1\|WP_004190791.1\|1715091_1715796_-\|SDR-family-oxidoreductase	gnl\|CDD\|187602	cd05344, BKR_like_SDR_like, putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR. This subgroup resembles the SDR family, but does not have a perfect match to the NAD-binding motif or the catalytic tetrad characteristic of the SDRs. It includes the SDRs, Q9HYA2 from Pseudomonas aeruginosa PAO1 and APE0912 from Aeropyrum pernix K1. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	7.06603e-71
NZ_CP010349.1\|WP_004190287.1\|1729963_1730812_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.00291e-102
NZ_CP010349.1\|WP_004537687.1\|1720399_1721074_-\|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	4.56369e-23
NZ_CP010349.1\|WP_004190530.1\|1738987_1739278_-\|H-NS-histone-family-protein	gnl\|CDD\|376390	pfam00816, Histone_HNS, H-NS histone family.	5.135e-20
NZ_CP010349.1\|WP_004190897.1\|1728637_1729780_+\|alpha-hydroxy-acid-oxidizing-protein	gnl\|CDD\|376451	pfam01070, FMN_dh, FMN-dependent dehydrogenase.	5.89768e-172
NZ_CP010349.1\|WP_004190252.1\|1721146_1721887_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.03262e-62
NZ_CP010349.1\|WP_004190485.1\|1727649_1728573_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	6.62225e-57

>NZ_CP010349.1|WP_004190661.1|1725642_1726977_+|MHS-family-MFS-transporter
MPTPTPGTPRPPRTPQPVRAALAAFIGTTVEFYDYYTYATAAALVLGDVFFPSDNPFVSTMASFATFFVGFVARPLSGAVFGHLGDRIGRKKMLVLTMFLMGAATTGIGLLPGYATIGVWAPVLLVLLRILQGIAVGGEWGGAVLMASEHASAGRRTLFASFPQMGSPAGLILSLLAFRYVTSLDHARFVAWGWRLPFLASFVLLLIGVAVRLGVNESPEFERVRDSHAVARFPVAEVLRTAWYPIVLAAAATTIGSAGFFFTNTFMISYVTTYLGMSKSFILDCLFAVTLIQLLSQPVSALLAQRFGETRFLVCAALLSMLTPYPMFVLVRTHDPVAIVAGIAFAVVALSAVYAVIAGFMSAAFPTRVRYSGISIAYQLCALVAGGTTPLVGTMIAQRYRGEWLPLALFFSLLAFVSLVGIVGLGRYRRNLHAVAPRTWAVNP
>NZ_CP010349.1|WP_009950654.1|1724791_1725190_-|hypothetical-protein
MTPDGCSDGCRRRAVRGGVDGLGVSVLAAMHGVSLSITTFSKNGGAVTVSGGAGDGGDIGMPSSDVAEERTPPNEVFGGVFGVEEMAIDACRLPEMKWRNVERIWMKPVPLRVRSMRDRSAVRLAGGVRCVS
>NZ_CP010349.1|WP_004190793.1|1723179_1724301_+|cysteine-desulfurase
MTHIYLDYNASTPIDPAVANAMRPLLPEAFGNPSSGHWASVPAKVALDRARAQVATLIGAAPDEIVFTSGGSEANNLALKGTVLASSNAGGHVITQSTEHPAILKPLQFLERLGTKVTCVPVDGNGRVDPDAIRRAITPRTTLITVMHANNETGTIQPIEDIGTIAREHGIRFHTDAAQSIGKIPADVDALGVDLLSIAGHKLYAPKGIGALYVRKGVGLEPLIHGAGHENGRRAGTESALLAAGFGEACALARDLAAMDGIRALRDRLWHALQDRFDDRVRLNGHLEYRLPNTVNVSFVGRVGTDVLAALDGVAASTGSACHAGRMTLSPVLAAMGIAEQVGMGAIRFSLGRHTTADEIDTVIAKLSAIARG
>NZ_CP010349.1|WP_004190526.1|1721891_1723133_+|MFS-transporter
MSKSTMPAGGAAIRLGLKENWRQFALLVLINAFVGGMVGIERTVVPLIGSETFHIQSTTLITSFIVSFGLVKAVANLISGQLADTWGRKRVLVAGWLLGLPVPFMIIAAPNWEWVIAANVLLGLSQGFAWSMTVIMKVDLVGPKARGLAVGLNEFAGYFAVGLTAFLTGYLASRHGLRPAPIYLGVAYAIAGLTLSILVVRDTRDHVCLEAGKPKEATSLSFHDVFLLASLKDRNLFAASQAGLINNLNDGMSWGIFPLFFTGLGLGVERIGILKAAYPIVWGVFQVVTGPLSDRWGRKGLIVAGMWVQAAGLVLTASMGEFRWWLVASVLLGLGTAMVYPSLIAAVSDASDPRWRARALSVYRFWRDLGYAIGALSAGLIADRFGFADAILSIAAVTFLSGAVVAIVMHARH
>NZ_CP010349.1|WP_004190252.1|1721146_1721887_+|MBL-fold-metallo-hydrolase
MILRQFLHCDPVGISYLLGCGGKSTGVVVDAVAEPGTYLQAAADAGMKIDYVIDTHVHADHLSTGPALADAAGAAYVLSTKADVVLPFKGVEDGDEIRVGNVVIKVLETPGHTPEHISLLVTDRTRAEEPWLALTGHTLMIGDLGRTELAESAEAGARNLFRSVRTLKSLPDYLPLLPGAFAGSACGRGLSATPLSTIGFEKRHNAAFGIDDEAAFVRFMLSDMPPAPPEAARLRAANSGRNPDEI
>NZ_CP010349.1|WP_004537687.1|1720399_1721074_-|metalloregulator-ArsR/SmtB-family-transcription-factor
MSSAGPKQEIYESLAEVAQAVGHPNRLELLEHLAQRERSVEDLTALSGMSFANTSRHLQILRRARLVDTERRGKNVVYRLAGDSEVVGLMKALGRLGERNVAEVNRVLGDYFHARDSMEPVSRNELTARLADGLVTLLDVRPHDEFAQGHLPGALNIPLAALEARLSELPADTEIVAYCRGPYCVLAFEAVAALRARGFKAARLEDGFPEWKAAGFVVETEPAN
>NZ_CP010349.1|WP_004536572.1|1719634_1719940_-|hypothetical-protein
MITVITSFQLPAPLAREEARSLFLRAAPKHQGVVGLCANTMSCRKAEGRVYLWNARAQAETMYTDAWKASAYETFGTFPSITYFESPAVVDNATNAIFSDE
>NZ_CP010349.1|WP_004190962.1|1718462_1719404_+|LysR-family-transcriptional-regulator
MDIKLDTPLLGALRCFEAAGRLGSFTKAADALHLTQSAISQQIRQLEARLGYPLFVRHARGLALTPKGGALHEATVAAFASLGRTLRQLSAPDAPLQVSCLPSFALQWLMPRLTEFHRLHPQTPVRLRAEFHAIDRETMSADDIDIAIRWDPFSYGALHVEPLFDESLVAAAAPAYLDRHPPRATAKWVSSVVPLHDASAWPEAPRYVEWRTWLDAVVPGYASALRGPEFNLASLAIAAAVAGQGVVVCREALVDDEIARGRLVNVFARRVPAPAQYKAICARPEDARVKAFVGWLRAESDSYAARRQTQARP
>NZ_CP010349.1|WP_004190523.1|1715977_1716892_+|LysR-family-transcriptional-regulator
MPARKPGRLPPLNALRAFEVSARHLNFRAAADEIGVTQGAVAQQVRHLEDALGVALFERLPRGLALTADGLAYFADVRRALNLIGDATDRLAKRRANVTISTTPSFASRWLIPRLASFGDEHRGVDLRVIADSQFATFQGDGVDLAIRYGKPPFGKGLVTRLLFPVDIYAVCSPALLAPPGALARARDLAGHALLHDAHDLWPEFLAALPERVAIDPAKGPRFNQSSLAIDAAIAGHGVALASDQLVARDIEAGRLRRLFDFALPLSVGYYIVRPSEPRRPGDIAQTEAWLIRQAQLDARRDGA
>NZ_CP010349.1|WP_004190791.1|1715091_1715796_-|SDR-family-oxidoreductase
MAVEKVALITAAGKGMGAAIARELASAGYRVALMSPSGSAVALAGELDGLGLRGSVTEEADLDRLVRETLARYGRIDAVVNNTGHPPKGELLSIADASWHDALDLILLNVAGLMRRVTPVFQAQGGGAAVNISSFAAVAPEQPMPVSSVLRAALGAWTRLYAERYAAENIRMNAVLPGFVDSWPETPGIVARIPAGRFGRTREIAKTVAFLLSDGAGYVTGQSIRVDGGIVRAM
>NZ_CP010349.1|WP_004190485.1|1727649_1728573_+|LysR-family-transcriptional-regulator
MNPSDLRDLRLPSLDGLLAFVAAARHGTFERAAEELCVTGSAVAKRVAALEQLLGVQLLVRSGKALTLTAAGNEYLHQVHAPLHLLAAVPLHRRNAGKTERLRICAPPTFARQILVARLDAFTLAHPGVELEVMLASPFPDAPPTGADLWIRGGGPIVSGATVLMVDALTPLAAPSLVERFAPLRRPADLAALPLLCTPLEPWTPWFRVAGLDWPEPANGPKLLDLGLLLEAAVSGQGVALGSPALARPWLAAGALVPLFPRIVRPAAPYYLMPYAPRAAAGAFAAWLADVCERAVRDGAEFLSRHG
>NZ_CP010349.1|WP_004190897.1|1728637_1729780_+|alpha-hydroxy-acid-oxidizing-protein
MSVPITCIEDLRVLAKKRIPRMFYDYVDTGSYTESTYRANEADFRKIRLRQRVGVDISNRNLRTTMAGQDVAMPVALAPTGLVGMMRADGEILAARAARHFGVPFTLSTMSICSIEDIVAHVGGPFWFQLYMMRDRAFIERLIERASAAGCPALVLTMDLQIAGQRHKDVKNGLSAPPRITLPNLLDMMRKPGWCLGMARTRRRHFGNIVGHVKGVTDMWSLDSWTREQFDPTIGWRDAEWVRRRWNGKLIVKGVLDADDALRAADAGADAIVVSNHGGRQLDGAMSSIEALPAIVEAAGKRVEVWLDGGVRTGQDVLKAVALGARGTMIGRAFLYGVAALGEQGARRALELIARELDTTMALCGCTDIRSVNADVLARR
>NZ_CP010349.1|WP_004190287.1|1729963_1730812_-|fumarylacetoacetate-hydrolase-family-protein
MKLLRYGPVGQEKPGLLDADGRIRDLSSLIDDVAGGALSDASLARLAAADPASLPLVAGEPRIGACVGRIGKFVCIGLNYADHAAEAGLAVPAEPVVFGKWTSAVSGPHDGIEIPRGSVKTDWEVELGVVIGRACKNVDEADALSHVAGYCVVNDVSEREWQIERGGQWDKGKGFDTFGPIGPWLVTRDEIADPQALDLWLDVDGRRYQSGNTRTMVFTVARLIAYLSRCMSLQPGDVISTGTPPGVGMGVKPSPVYLKPGQTVRCGVAGLGEQQQRTRAAA
>NZ_CP010349.1|WP_162186992.1|1730951_1731116_+|hypothetical-protein
MQQTLAMRGFTGGDRVPPARAAVASGLAGARAPARGHTVPRRLAGFFRPSRRIL
>NZ_CP010349.1|WP_004190404.1|1731322_1732147_+|IclR-family-transcriptional-regulator
MKPRKDAPAGAAQAPHDCEEIERYRAPALDKGLDILELLAEQKEGLTRTEITKELGRNASEIYRMLERLVARQYVIRSPGGDRYTLSLKLYSLAHRHPPLKRLIAEALPPMQRFADAAEQSCHLCVYDRGNLLVIAQVDGPGAWGISVRLGSRVGLVDTASGPVLLAFQTPEQRARMLVEHTKVEGEIALDMREFDALLHEIRATGRLRQKSRQAFGVTDIAYPVLGPSGHAIAALTCPYVRRIDTHAAPCAEDVDAQLRATARHLSMLKEAAA
>NZ_CP010349.1|WP_004553904.1|1732437_1733841_+|indoleacetamide-hydrolase
MTSHRDTYVRSASVRAIADAVNGRRVRALEQAEAALERLALVEPLAAMTHVAPEIARRAAANVDAQIASGRRLPLAGVPFVIKDNLFTADMPTRAASPALLGFDATRNATAVQQLLDAGAVPLGKANMHELAFGITSANGYFGAVRNPHDPARIAGGSSGGTACAVAAGIAFGLGTDTGGSVRIPAAFCGVAGLRPTPRRYSTEGVLALSPTRDTVGPIAHGIDDLLLLDAVLTGDAGEPAPVALAGLRVGVPDAPYFDGLDPAVAELTERALAALTDAGARLIPLAAHALHEADEACGFPIAGFEALAYWRRFSAERLDLPFAEFVARLGSDDVRHLFRMLIDAPPSSDAYAAAIDVLQSTVRWYDQAFHRTGVDCIALPTVQCDAPLVTDSGHDLPSDAAYALFARVIRQTGPATLGGVPSVSIPAGLSKHTGVPVGLMLEGPAGNDRRLLAIAREVERLLARAP
>NZ_CP010349.1|WP_004266659.1|1734026_1734578_+|hypothetical-protein
MDVMAKLLTDLEFQRFSELQQKQASFTITPEEADELRDIVARAQKKRDDRASAMRAIEAYIAQFDITPDELFSPEQIGEAARTYGLIAAGKKERSLPPSLTFNGKPYQWTKTLPDEVRLPLFDAFKAGESIKRFIAMPKDAARCALTVARLERETGAVYADTLLDELAISRKHVEEAAAKLAA
>NZ_CP010349.1|WP_004190255.1|1735082_1737446_-|GNAT-family-N-acetyltransferase
MTVRNLDALFHPTSVAVVGASPRPGSVGAMVWACVLDGRFGGAIWPVNPKYGELNGHKVYPYVDQLPSAPSVALICTPPATWPGIVRKLGGLGVRAAIIVGEARSGADRAALERALAAAKPYLLRVVGPGSLGVVSPALGAHFGAPACIVKAGGVAWVSQSNALTNAVLGWAHARGLGFSHAVALGGEADVDAADVLDYLASDAETRAILLELDTVKSARKFMSAARAAARNKPVLALRAGRGDSGDLLYTAAFQRAGMVRVDALDDLLDEIEALGVGRAAATSGGVTLVTSDRGVAKLAVDALAAAGETLAQWPRAAVDEVGGALPAGIVAGNPLLLGDDARPEYFGAALKALAQHPPTGTVFVVHATSHSAPAVDVARVLIESRKFARRGMLACFFGGVDAATRDALHVHGIPVHTTPQRLARAHARLVDYQLGRELLMQTPEGTPPQPAASISAARHTARAALAQGRDGFEGDAALEWLAGFGIERATDADVDMGDTIVDITVGMYDDPNFGPVFRYSVPPADGVSAPFVVYGLPPFNTVLARAVVARSPYAHRAPPEPLLQALTALSQAVCDVREIVEMSLVLRVRPTRVVALGPHIRLATGRSRLAIVPYPRYLEQQLDWRGERITVRPIRPEDEAAHRELLSAMTPDDLRMRFFGAIRNFDHSQIARMTQIDYDREMALIATLDDADGRAHTLGAVRAVTDPDNEATEFAIAVRPDQKGKGLGRMLMTRIIDYARSRGTAWMIGEALRENTAMISLAKDSGFAVSSTEEPGVVAFRLKLQP
>NZ_CP010349.1|WP_162473499.1|1737987_1738881_+|hypothetical-protein
MLKRPSRNIGPAGSGIENGGPANSMHCPIAGNRRAGQKIAVQSSERRGPPLTRFEFNAQCHCAISVKYENNGDTRHECRANLRSRPRTEAPLAIPLPPPLRQASKLREPAWQAVEERLFGENSGISFMPATVRRDSIAARMRKLSRKCRLHGFAVHVRWLFPPPGWPIRTDKWRYHALSARRRFSGIAVEHALAARIECETARRKRRGDTRHAPPKVSVFGSQGEAIRDWVSSFGEIARLPRQNRKRRSKWMRRRETFGSIRQVRIDGRIARHPPERIGFIAESTHNPLRREIAGPP
>NZ_CP010349.1|WP_004190530.1|1738987_1739278_-|H-NS-histone-family-protein
MATYRQLTAQLEKLQQKIDKEREKAITDAIADIKAKIEEYDITPEELGFRSVKAAAKPKRALPPKYLNPKTGETWSGRGRAPAWLGKNRNRFLIKD

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Crispr_ID: NZ_CP010349_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010349_3

1999268-1999413

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP010349_3

>merge|NZ_CP010349|3|1999268-1999413|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NZ_CP010349|3|1|1999268-1999413|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NZ_CP010349|3|3|1999318-1999403|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010349.1\|WP_004187137.1\|2009002_2009452_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NZ_CP010349.1\|WP_004187216.1\|1995792_1998066_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NZ_CP010349.1\|WP_004205325.1\|1993583_1995482_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP010349.1\|WP_004187305.1\|2005762_2006794_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236122
NZ_CP010349.1\|WP_004205322.1\|1991975_1992911_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NZ_CP010349.1\|WP_011807545.1\|1989213_1989816_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004188034.1\|1999970_2001236_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NZ_CP010349.1\|WP_011204701.1\|2010626_2011061_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NZ_CP010349.1\|WP_004529492.1\|2001520_2003362_+\|ribonucleotide-reductase-like-protein	unknown	unknown	gnl\|CDD\|180772
NZ_CP010349.1\|WP_004187710.1\|2003436_2005239_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NZ_CP010349.1\|WP_004188282.1\|1986261_1987305_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP010349.1\|WP_004196918.1\|2008784_2009006_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004200700.1\|1990562_1991678_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378454
NZ_CP010349.1\|WP_004200699.1\|1987310_1988543_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NZ_CP010349.1\|WP_004200705.1\|2009905_2010559_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NZ_CP010349.1\|WP_004188488.1\|1993326_1993524_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010349.1\|WP_004188244.1\|2011466_2012597_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_CP010349.1\|WP_004187792.1\|2006790_2008623_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NZ_CP010349.1\|WP_004196898.1\|1989787_1990228_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NZ_CP010349.1\|WP_004187469.1\|1998198_1998594_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|224648

Protein	Function_ID	Function_description	E-value
NZ_CP010349.1\|WP_004187137.1\|2009002_2009452_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.39507e-50
NZ_CP010349.1\|WP_004187216.1\|1995792_1998066_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	7.15563e-57
NZ_CP010349.1\|WP_004205325.1\|1993583_1995482_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	1.20731e-34
NZ_CP010349.1\|WP_004187305.1\|2005762_2006794_+\|hypothetical-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	5.74738e-30
NZ_CP010349.1\|WP_004205322.1\|1991975_1992911_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.67997e-62
NZ_CP010349.1\|WP_004188034.1\|1999970_2001236_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	1.36366e-112
NZ_CP010349.1\|WP_011204701.1\|2010626_2011061_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	2.04683e-32
NZ_CP010349.1\|WP_004529492.1\|2001520_2003362_+\|ribonucleotide-reductase-like-protein	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NZ_CP010349.1\|WP_004187710.1\|2003436_2005239_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	9.00049e-75
NZ_CP010349.1\|WP_004188282.1\|1986261_1987305_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NZ_CP010349.1\|WP_004200700.1\|1990562_1991678_-\|hypothetical-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NZ_CP010349.1\|WP_004200699.1\|1987310_1988543_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	8.93075e-143
NZ_CP010349.1\|WP_004200705.1\|2009905_2010559_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	6.31252e-20
NZ_CP010349.1\|WP_004188244.1\|2011466_2012597_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	2.53339e-55
NZ_CP010349.1\|WP_004187792.1\|2006790_2008623_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.60835e-107
NZ_CP010349.1\|WP_004196898.1\|1989787_1990228_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	3.1145e-25
NZ_CP010349.1\|WP_004187469.1\|1998198_1998594_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14

>NZ_CP010349.1|WP_004187469.1|1998198_1998594_-|conjugal-transfer-protein-TraR
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NZ_CP010349.1|WP_004187216.1|1995792_1998066_-|FAD-dependent-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NZ_CP010349.1|WP_004205325.1|1993583_1995482_+|GMC-family-oxidoreductase
MLGATRSTLWGSRERPRIAAARAPGAAAIRMREEARECAGPRGAGRAPHRATAAGGKTGRRTVRAPSRARAGSNNQKVNRMKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLHGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPNKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NZ_CP010349.1|WP_004188488.1|1993326_1993524_+|hypothetical-protein
MAQTPIGAAGAISPSTARSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NZ_CP010349.1|WP_004205322.1|1991975_1992911_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NZ_CP010349.1|WP_004200700.1|1990562_1991678_-|hypothetical-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NZ_CP010349.1|WP_004196898.1|1989787_1990228_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDERRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NZ_CP010349.1|WP_011807545.1|1989213_1989816_+|hypothetical-protein
MNSILAPDNAPPASATRTSPLMSVLARAVVTAPLPGSGRAAEASTRVSTMRAQSASAIRIRSCRRSRSSRHGLPESPACRRKSPARPRSRRAPRPLADHTRMRFSPPRLGVRTARPPPAGRSKPARGASAIRLRVQRRSSRLTMTLINVIVIARAPQTAIVTHRGIGPRAIGRLTARRRAARPSTLETRPSYETATHRNR
>NZ_CP010349.1|WP_004200699.1|1987310_1988543_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGMLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NZ_CP010349.1|WP_004188282.1|1986261_1987305_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTASKEGPAASPMTMIQALRSAMDVMLERDGNVVVFGQDVGYFGGVFRCTEGLQNKYGKSRVFDAPINEGGIVGAAVGMGAYGLRPVCEIQFADYFYPASDQIVSEAARLRYRSAAEFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLISAIENDDPVIFLEPKRLYNGPFDGHHERPVTPWSKHPASLVPDGYYTVPLDSAAIVRAGGDVTVLTYGTTVHVSLAAAEETGIDAEVIDLRSLWPLDLDTIVESVRRTGRCVVVHEATRTCGFGAELIALVQEHCFHWLEAPVERVTGWDTPYPHAQEWAYFPGPNRVGDALRRAMEN
>NZ_CP010349.1|WP_004188034.1|1999970_2001236_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWTAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NZ_CP010349.1|WP_004529492.1|2001520_2003362_+|ribonucleotide-reductase-like-protein
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIDATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NZ_CP010349.1|WP_004187710.1|2003436_2005239_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFTELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDAARVDAQATR
>NZ_CP010349.1|WP_004187305.1|2005762_2006794_+|hypothetical-protein
METSPLKTTTPEAIPPFNPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGFAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVATGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NZ_CP010349.1|WP_004187792.1|2006790_2008623_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGATLTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NZ_CP010349.1|WP_004196918.1|2008784_2009006_-|hypothetical-protein
MTDAVVSSRLAPCCVYIDIQGEGDVDVDAEGNGNGNIDVIDSKRCEPSGVEPVERAVRRPRYRAQSGCLSGIH
>NZ_CP010349.1|WP_004187137.1|2009002_2009452_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKEVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NZ_CP010349.1|WP_004200705.1|2009905_2010559_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDIYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NZ_CP010349.1|WP_011204701.1|2010626_2011061_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFRGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NZ_CP010349.1|WP_004188244.1|2011466_2012597_-|porin
MMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP010349_2	2.2\|1727293\|20\|NZ_CP010349\|CRISPRCasFinder	1727293-1727312	20	NZ_CP010349.1	1727325-1727344	0	1.0
NZ_CP010349_2	2.2\|1727293\|20\|NZ_CP010349\|CRISPRCasFinder	1727293-1727312	20	NZ_CP010349.1	1727333-1727352	0	1.0
NZ_CP010349_2	2.2\|1727293\|20\|NZ_CP010349\|CRISPRCasFinder	1727293-1727312	20	NZ_CP010349.1	1727341-1727360	0	1.0
NZ_CP010349_2	2.2\|1727293\|20\|NZ_CP010349\|CRISPRCasFinder	1727293-1727312	20	NZ_CP010349.1	1181708-1181727	2	0.9
NZ_CP010349_2	2.2\|1727293\|20\|NZ_CP010349\|CRISPRCasFinder	1727293-1727312	20	NZ_CP010349.1	1181716-1181735	2	0.9

1. spacer 2.2|1727293|20|NZ_CP010349|CRISPRCasFinder matches to position: 1727325-1727344, mismatch: 0, identity: 1.0

gacagcacgacagcacgaca	CRISPR spacer
gacagcacgacagcacgaca	Protospacer
********************

2. spacer 2.2|1727293|20|NZ_CP010349|CRISPRCasFinder matches to position: 1727333-1727352, mismatch: 0, identity: 1.0

gacagcacgacagcacgaca	CRISPR spacer
gacagcacgacagcacgaca	Protospacer
********************

3. spacer 2.2|1727293|20|NZ_CP010349|CRISPRCasFinder matches to position: 1727341-1727360, mismatch: 0, identity: 1.0

gacagcacgacagcacgaca	CRISPR spacer
gacagcacgacagcacgaca	Protospacer
********************

4. spacer 2.2|1727293|20|NZ_CP010349|CRISPRCasFinder matches to position: 1181708-1181727, mismatch: 2, identity: 0.9

gacagcacgacagcacgaca	CRISPR spacer
gaccgcacgacaacacgaca	Protospacer
*** ********.*******

5. spacer 2.2|1727293|20|NZ_CP010349|CRISPRCasFinder matches to position: 1181716-1181735, mismatch: 2, identity: 0.9

gacagcacgacagcacgaca	CRISPR spacer
gaccgcacgaccgcacgaca	Protospacer
*** ******* ********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

171056 : 214783

Streptococcus_phage(40.0%)

transposase,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|171056_172520_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004554722.1\|172658_173558_-	glutamate/aspartate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004196258.1\|173721_174969_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_004188170.1\|175121_176054_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004188660.1\|176598_177339_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_004202300.1\|177358_177643_+	hypothetical protein	NA	NA	NA	NA
WP_004187552.1\|177782_178148_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004196252.1\|178589_180506_+	hypothetical protein	NA	NA	NA	NA
WP_004188385.1\|180717_183678_+	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_011204674.1\|183705_183936_+	hypothetical protein	NA	NA	NA	NA
WP_004187628.1\|184242_185463_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5
WP_004188150.1\|185592_186651_+	L-tyrosine/L-tryptophan isonitrile synthase family protein	NA	NA	NA	NA
WP_004187705.1\|187576_189061_+	Pyoverdin chromophore biosynthetic protein pvcC	NA	NA	NA	NA
WP_004187879.1\|189106_190975_+	asparagine synthase (glutamine-hydrolyzing)	A0A1V0SHV8	Klosneuvirus	1.9e-18	23.1
WP_004187502.1\|191003_191975_+	quinone oxidoreductase	A0A2P1ELD9	Moumouvirus	6.6e-07	25.2
WP_004187006.1\|192029_192956_+	catecholic dioxygenase	NA	NA	NA	NA
WP_004196246.1\|193198_194545_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004188288.1\|195130_195361_-	hypothetical protein	NA	NA	NA	NA
WP_004188530.1\|199484_200750_-	type VI secretion system protein TssL	NA	NA	NA	NA
WP_004188743.1\|200838_202185_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004187276.1\|202206_202710_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004188308.1\|202816_203302_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004188012.1\|203418_204918_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004196243.1\|204952_205534_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_011204222.1\|207691_209155_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	2.0e-79	38.3
WP_004188539.1\|210586_211333_+	TagK domain-containing protein	NA	NA	NA	NA
WP_004187921.1\|211329_212295_+	ImpE/SciE family protein	NA	NA	NA	NA
WP_004187068.1\|212281_212863_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004187986.1\|212893_214783_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_2

383934 : 454713

Acinetobacter_phage(45.45%)

transposase,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004521984.1\|383934_385233_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_004200645.1\|385524_385836_+	hypothetical protein	NA	NA	NA	NA
WP_004198580.1\|385832_386087_+	hypothetical protein	NA	NA	NA	NA
WP_004186938.1\|386105_387920_+	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	3.0e-170	49.6
WP_004186966.1\|388056_388608_+	cysteine hydrolase	NA	NA	NA	NA
WP_004186915.1\|388604_389228_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_004186903.1\|389563_391231_-	energy-dependent translational throttle protein EttA	A0A1V0SKJ1	Klosneuvirus	2.2e-42	27.2
WP_004186876.1\|391517_391829_-	DUF3761 domain-containing protein	NA	NA	NA	NA
WP_004202137.1\|391968_392946_+	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
WP_004198399.1\|393061_393541_+	hypothetical protein	NA	NA	NA	NA
WP_004186796.1\|393698_393920_+	hypothetical protein	NA	NA	NA	NA
WP_004186864.1\|394203_395607_+	GABA permease	NA	NA	NA	NA
WP_004186854.1\|395678_396512_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004186860.1\|396525_397029_-	NADH-quinone oxidoreductase subunit B	NA	NA	NA	NA
WP_004206632.1\|397243_397525_+	hypothetical protein	NA	NA	NA	NA
WP_004186874.1\|397635_398730_-	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_004186799.1\|399255_399621_-	hypothetical protein	NA	NA	NA	NA
WP_004557275.1\|399629_399986_-	hypothetical protein	NA	NA	NA	NA
WP_004266669.1\|400077_400206_-	lipoprotein	NA	NA	NA	NA
WP_004521997.1\|400520_401702_+	UbiH/UbiF family hydroxylase	NA	NA	NA	NA
WP_004186839.1\|402627_404457_+	M61 family metallopeptidase	NA	NA	NA	NA
WP_004549943.1\|404595_405192_+	FMN-dependent NADH-azoreductase	NA	NA	NA	NA
WP_004186801.1\|405410_406190_-	uracil-DNA glycosylase	A0A060Q589	Fruit_bat_alphaherpesvirus	6.4e-53	51.1
WP_004186832.1\|406231_406873_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_004186826.1\|406883_407669_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	9.3e-52	46.7
WP_004186823.1\|407731_408763_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.6e-80	47.0
WP_004186792.1\|408780_409371_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.4e-68	60.0
WP_004186866.1\|409384_410878_-	anthranilate synthase component I	NA	NA	NA	NA
WP_004186872.1\|411240_411969_-	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_004186923.1\|411965_412661_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_004522004.1\|412707_412917_-	hypothetical protein	NA	NA	NA	NA
WP_004186878.1\|412842_413217_+	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_038719768.1\|413325_414552_+	hypothetical protein	NA	NA	NA	NA
WP_004186945.1\|414879_416178_-	phenylacetate--CoA ligase	NA	NA	NA	NA
WP_004186957.1\|416691_417483_-	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase	NA	NA	NA	NA
WP_004522007.1\|417541_418744_-	3-oxoadipyl-CoA thiolase	NA	NA	NA	NA
WP_004186941.1\|418832_420539_-	phenylacetic acid degradation protein PaaN	NA	NA	NA	NA
WP_004198410.1\|420669_421446_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_073699529.1\|421842_421959_+	phenylacetate-CoA oxygenase	NA	NA	NA	NA
WP_096325434.1\|427577_428697_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004184834.1\|428938_430399_+	ser/threonine protein phosphatase	NA	NA	NA	NA
WP_009967729.1\|431977_432910_+	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_011326545.1\|433353_434043_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.2e-12	28.8
WP_024900894.1\|434074_434809_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|442603_443724_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004266245.1\|444282_445353_-	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_004184680.1\|445415_445910_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	2.5e-26	44.6
WP_004184724.1\|445944_446424_-	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_004198701.1\|446420_446756_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004266244.1\|447227_448127_-	hypothetical protein	NA	NA	NA	NA
WP_004198708.1\|448225_448441_-	hypothetical protein	NA	NA	NA	NA
WP_004198711.1\|448816_449008_-	hypothetical protein	NA	NA	NA	NA
WP_004555731.1\|449034_449697_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_162490682.1\|449930_451646_+\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.9e-26	33.8
WP_004200833.1\|451638_452541_+\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_004199315.1\|452663_453662_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004533171.1\|453762_454713_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_3

594614 : 651623

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|594614_596078_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004551552.1\|596280_597117_-	universal stress protein	NA	NA	NA	NA
WP_004200939.1\|597116_597611_-	universal stress protein	NA	NA	NA	NA
WP_004200941.1\|597792_598632_-	universal stress protein	NA	NA	NA	NA
WP_004200942.1\|598881_599922_+	zinc-dependent alcohol dehydrogenase family protein	A0A0K0KVL7	Prochlorococcus_phage	2.4e-10	23.5
WP_004200943.1\|600289_601435_+	cytochrome P460	NA	NA	NA	NA
WP_004200944.1\|601623_602832_+	MFS transporter	NA	NA	NA	NA
WP_004184941.1\|603236_604013_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004200946.1\|604028_604898_+	hypothetical protein	NA	NA	NA	NA
WP_004200950.1\|605741_607157_+	amino acid permease	NA	NA	NA	NA
WP_004200952.1\|607752_607995_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004184704.1\|608145_608436_+	H-NS histone family protein	F8TUP5	EBPR_podovirus	4.4e-07	37.8
WP_024901083.1\|608829_610146_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004201904.1\|610567_611065_-	hypothetical protein	NA	NA	NA	NA
WP_004266679.1\|611182_612067_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_038802950.1\|612177_613298_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198724.1\|614319_616374_-	sugar phosphate isomerase/epimerase and 4-hydroxyphenylpyruvate domain-containing protein	NA	NA	NA	NA
WP_004204041.1\|616633_617089_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_004194708.1\|617085_617940_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_004194588.1\|617987_619334_+	MFS transporter	NA	NA	NA	NA
WP_004194610.1\|619735_620845_-	2-aminoethylphosphonate--pyruvate transaminase	NA	NA	NA	NA
WP_004194640.1\|621082_622165_+	2-aminoethylphosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004194602.1\|622221_623319_+	2-aminoethylphosphonate ABC transport system ATP-binding subunit PhnT	G3M9Y6	Bacillus_virus	5.5e-26	32.5
WP_004194612.1\|623296_624244_+	2-aminoethylphosphonate ABC transporter permease subunit	NA	NA	NA	NA
WP_004194685.1\|624233_625094_+	2-aminoethylphosphonate ABC transport system, membrane component PhnV	NA	NA	NA	NA
WP_004199121.1\|625137_626409_+	phosphonoacetate hydrolase	NA	NA	NA	NA
WP_004194628.1\|626405_627860_+	phosphonoacetaldehyde dehydrogenase	NA	NA	NA	NA
WP_004194622.1\|627864_628416_+	HD domain-containing protein	NA	NA	NA	NA
WP_073699529.1\|628855_628972_+	phenylacetate-CoA oxygenase	NA	NA	NA	NA
WP_038802950.1\|634569_635690_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198117.1\|635860_636007_+	DUF3563 family protein	NA	NA	NA	NA
WP_011204222.1\|636131_637595_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	2.0e-79	38.3
WP_004198119.1\|637803_638082_+	hypothetical protein	NA	NA	NA	NA
WP_004198120.1\|638094_638940_-	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_004198121.1\|639088_640060_-	NADP-dependent aryl-alcohol dehydrogenase	NA	NA	NA	NA
WP_004266709.1\|640247_641036_+	3-hydroxybutyrate dehydrogenase	NA	NA	NA	NA
WP_004191998.1\|641240_642704_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004198124.1\|642847_644047_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_004199587.1\|644334_646425_+	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_004266710.1\|646648_647200_+	membrane protein	NA	NA	NA	NA
WP_004198127.1\|647259_647589_+	cupredoxin domain-containing protein	NA	NA	NA	NA
WP_004198128.1\|647648_648491_+	iron transporter OFeT family	NA	NA	NA	NA
WP_004198129.1\|648487_649888_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_004199588.1\|649947_650358_+	heme-binding protein	NA	NA	NA	NA
WP_038802333.1\|650503_651623_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_4

1618438 : 1693136

Leptospira_phage(23.08%)

transposase,tRNA,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004203245.1\|1618438_1619251_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_004203246.1\|1619250_1621878_-	membrane protein	NA	NA	NA	NA
WP_004188178.1\|1622013_1623135_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_004525190.1\|1623133_1623295_+	hypothetical protein	NA	NA	NA	NA
WP_004187693.1\|1623476_1624544_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_004187882.1\|1624592_1625243_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_004187125.1\|1625320_1625470_-	entericidin A/B family lipoprotein	NA	NA	NA	NA
WP_004187091.1\|1625466_1626876_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_004187288.1\|1627267_1628563_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_004187652.1\|1628555_1629503_-	hypothetical protein	NA	NA	NA	NA
WP_004187998.1\|1630222_1630750_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_004187349.1\|1630910_1633634_+	alpha-ketoglutarate dehydrogenase	NA	NA	NA	NA
WP_004188364.1\|1633885_1635130_-	DUF1479 domain-containing protein	NA	NA	NA	NA
WP_096325434.1\|1636341_1637461_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200651.1\|1637472_1637616_-	hypothetical protein	NA	NA	NA	NA
WP_004187842.1\|1637691_1638666_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004188362.1\|1638762_1640064_-	citrate (Si)-synthase	NA	NA	NA	NA
WP_004188825.1\|1640116_1640389_-	succinate dehydrogenase assembly factor 2	NA	NA	NA	NA
WP_004187935.1\|1640390_1641092_-	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_004188402.1\|1641113_1642889_-	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_004187439.1\|1642893_1643262_-	succinate dehydrogenase, hydrophobic membrane anchor protein	NA	NA	NA	NA
WP_004536542.1\|1643266_1643683_-	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
WP_004196014.1\|1643882_1644692_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_004187735.1\|1644981_1645965_+	malate dehydrogenase	NA	NA	NA	NA
WP_004188261.1\|1646162_1647182_+	lyase	NA	NA	NA	NA
WP_004188791.1\|1647338_1647848_+	hypothetical protein	NA	NA	NA	NA
WP_004188028.1\|1647924_1649376_+	bifunctional 2-methylcitrate dehydratase/aconitate hydratase	NA	NA	NA	NA
WP_004187807.1\|1649423_1652141_+	aconitate hydratase AcnA	NA	NA	NA	NA
WP_004187717.1\|1652387_1655105_-	filamentous hemagglutinin N-terminal domain-containing protein	A0A0R6PJK4	Moraxella_phage	2.0e-13	25.2
WP_004188259.1\|1655205_1656870_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_004204352.1\|1656893_1657166_-	hypothetical protein	NA	NA	NA	NA
WP_096325434.1\|1657461_1658581_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004196172.1\|1660013_1661273_-	ABC transporter permease	Q6GZ02	Mycoplasma_phage	2.1e-05	22.6
WP_004190781.1\|1661373_1662420_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004190757.1\|1662494_1663595_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	6.3e-22	51.0
WP_004200631.1\|1663703_1665233_+	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	2.2e-12	25.9
WP_004196164.1\|1666327_1667353_-	triacylglycerol lipase	NA	NA	NA	NA
WP_004190808.1\|1667703_1669941_-	TonB-dependent copper receptor	NA	NA	NA	NA
WP_004190837.1\|1670028_1670424_-	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_004190603.1\|1670584_1671121_-	cytochrome b	NA	NA	NA	NA
WP_004190805.1\|1671389_1672025_+	hypothetical protein	NA	NA	NA	NA
WP_011204344.1\|1672155_1672920_-	peptidoglycan DD-metalloendopeptidase family protein	I2E8W3	Clostridium_phage	4.7e-08	38.7
WP_004190911.1\|1673198_1673510_-	cupin domain-containing protein	NA	NA	NA	NA
WP_011204342.1\|1673954_1674287_-	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_004190614.1\|1674485_1675901_-	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.1e-41	30.2
WP_004190588.1\|1675889_1676033_+	hypothetical protein	NA	NA	NA	NA
WP_004190461.1\|1676356_1677034_-	DUF938 domain-containing protein	NA	NA	NA	NA
WP_004190245.1\|1676996_1677935_-	NAD-dependent protein deacetylase	S5M4R0	Bacillus_phage	1.4e-14	25.3
WP_004190776.1\|1677931_1679356_-	cytosine permease	NA	NA	NA	NA
WP_011204340.1\|1679872_1680853_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_045589205.1\|1680865_1681627_+	acyltransferase family protein	A0A2H4IZR3	uncultured_Caudovirales_phage	1.2e-16	34.4
WP_038802950.1\|1681526_1682646_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004196154.1\|1682674_1683733_-	RHS repeat protein	NA	NA	NA	NA
WP_004196151.1\|1683662_1684316_-	hypothetical protein	NA	NA	NA	NA
WP_004203275.1\|1684390_1686595_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004203276.1\|1686591_1689246_-	type VI secretion system ATPase TssH	A0A1S6UBG5	Serratia_phage	2.7e-79	30.9
WP_004190820.1\|1689224_1690703_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004190509.1\|1690699_1692571_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004196148.1\|1692575_1693136_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_5

1768762 : 1828131

Leptospira_phage(22.22%)

transposase,integrase,portal,tRNA

attL 1760478:1760537|attR 1822817:1823767

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1760478:1760537	attL	NA	NA	NA	NA
WP_011204325.1\|1768762_1769803_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.7e-93	53.1
WP_004195713.1\|1770193_1771003_-	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_004266656.1\|1771153_1773058_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_004190235.1\|1773141_1774026_-	(2E,6E)-farnesyl diphosphate synthase	NA	NA	NA	NA
WP_004190549.1\|1774022_1774316_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_004190814.1\|1774585_1775692_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004191998.1\|1775842_1777306_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004190656.1\|1777430_1778300_+	sulfurtransferase	NA	NA	NA	NA
WP_004190499.1\|1778358_1779234_-	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_004204467.1\|1779386_1779608_-	hypothetical protein	NA	NA	NA	NA
WP_038763983.1\|1779947_1781741_+	membrane protein	NA	NA	NA	NA
WP_004190401.1\|1782102_1783485_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_004190446.1\|1783803_1786584_-	DNA polymerase I	A0A1J0GVZ7	Streptomyces_phage	5.6e-51	31.0
WP_004530319.1\|1786585_1787335_+	TIGR00730 family Rossman fold protein	A0A1D8KUT5	Synechococcus_phage	5.6e-22	37.8
WP_004190924.1\|1787331_1787601_+	hypothetical protein	NA	NA	NA	NA
WP_004190916.1\|1787752_1788037_+	hypothetical protein	NA	NA	NA	NA
WP_004190352.1\|1788696_1789188_+	DUF523 domain-containing protein	NA	NA	NA	NA
WP_004203322.1\|1789623_1789887_-	hypothetical protein	NA	NA	NA	NA
WP_096325434.1\|1791791_1792911_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_009950031.1\|1793468_1793756_+\|portal	phage portal protein	K4NZV0	Burkholderia_phage	6.4e-43	94.4
WP_004195697.1\|1793752_1794439_+\|integrase	tyrosine-type recombinase/integrase	E5E3N4	Burkholderia_phage	3.3e-93	81.6
WP_004190957.1\|1794522_1796049_-	AMP nucleosidase	NA	NA	NA	NA
WP_004190726.1\|1796204_1796603_+	hypothetical protein	NA	NA	NA	NA
WP_004190439.1\|1796696_1797692_+	homoserine kinase	NA	NA	NA	NA
WP_004190835.1\|1797682_1798495_+	hypothetical protein	NA	NA	NA	NA
WP_038730270.1\|1798626_1798878_-	hypothetical protein	NA	NA	NA	NA
WP_004190487.1\|1798997_1799450_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011832128.1\|1799587_1800007_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_004190391.1\|1800119_1800278_-	DUF3563 domain-containing protein	NA	NA	NA	NA
WP_004190691.1\|1800374_1801523_-	PHB depolymerase family esterase	NA	NA	NA	NA
WP_004204469.1\|1801773_1802472_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_004195689.1\|1802912_1803713_+	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004190258.1\|1803725_1804400_+	molybdate ABC transporter permease subunit	NA	NA	NA	NA
WP_004190506.1\|1804401_1805103_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.9e-20	32.3
WP_004190826.1\|1805646_1806495_-	TOBE domain-containing protein	NA	NA	NA	NA
WP_004195687.1\|1806529_1808452_-	CHAD domain-containing protein	NA	NA	NA	NA
WP_004190990.1\|1808649_1809033_-	tautomerase family protein	NA	NA	NA	NA
WP_004190343.1\|1809130_1810006_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004190540.1\|1810072_1810993_+	DMT family transporter	NA	NA	NA	NA
WP_004190659.1\|1811085_1811865_+	sensor histidine kinase	NA	NA	NA	NA
WP_004190954.1\|1811950_1813291_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_004190469.1\|1813287_1813917_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_004190582.1\|1814075_1815719_-	DUF3459 domain-containing protein	NA	NA	NA	NA
WP_004190434.1\|1817002_1817458_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_004190743.1\|1817522_1818761_-	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_004195676.1\|1819013_1819424_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004190802.1\|1819665_1820259_-	LysE family translocator	NA	NA	NA	NA
WP_004533441.1\|1820354_1821209_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004195671.1\|1821439_1821766_+	hypothetical protein	NA	NA	NA	NA
WP_004190721.1\|1821948_1822836_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|1822863_1823984_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
1822817:1823767	attR	NA	NA	NA	NA
WP_004190833.1\|1824049_1825129_-	putative membrane protein	NA	NA	NA	NA
WP_004190269.1\|1827126_1828131_-\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP010348

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

405375 : 442955

Streptococcus_phage(20.0%)

transposase,plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|405375_406839_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004198200.1\|406972_408037_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_011807805.1\|408282_408951_+	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_004198198.1\|409044_409596_+	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_004198197.1\|409789_410650_+	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_004198195.1\|411717_412098_+	response regulator	NA	NA	NA	NA
WP_011204177.1\|412129_414433_+	chemotaxis protein CheA	NA	NA	NA	NA
WP_004199265.1\|414463_414991_+	chemotaxis protein CheW	NA	NA	NA	NA
WP_004202799.1\|415031_417053_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.2e-12	41.9
WP_011832274.1\|417056_418004_+	chemotaxis protein methyltransferase	NA	NA	NA	NA
WP_004198646.1\|418000_418705_+	chemoreceptor glutamine deamidase CheD	NA	NA	NA	NA
WP_004200023.1\|418701_419805_+	chemotaxis response regulator protein-glutamate methylesterase	NA	NA	NA	NA
WP_004185006.1\|420153_420549_+	chemotaxis protein CheY	Q56AR1	Bacillus_thuringiensis_phage	2.7e-07	32.8
WP_004524402.1\|420550_421279_+	protein phosphatase CheZ	NA	NA	NA	NA
WP_004198643.1\|421476_421980_+	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_004198642.1\|422002_423253_+	DUF3443 domain-containing protein	NA	NA	NA	NA
WP_004198641.1\|423439_423940_+	VOC family protein	NA	NA	NA	NA
WP_004198640.1\|424647_425853_+	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_004198639.1\|425849_427952_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_123784499.1\|427932_428472_-	hypothetical protein	NA	NA	NA	NA
WP_004198638.1\|428567_429692_+	flagellar biosynthesis protein FlhF	NA	NA	NA	NA
WP_004198637.1\|429684_430497_+	flagellar biosynthesis protein FlhG	NA	NA	NA	NA
WP_004198636.1\|430518_431253_+	RNA polymerase sigma factor FliA	NA	NA	NA	NA
WP_004198634.1\|431606_433028_+	adenosylhomocysteinase	S4VPF6	Pandoravirus	7.6e-44	30.1
WP_004198632.1\|433191_433545_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_004198631.1\|433562_434393_+	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_038798086.1\|434576_436067_-	6-aminohexanoate hydrolase	NA	NA	NA	NA
WP_004198629.1\|436163_436856_-	carboxymethylenebutenolidase	NA	NA	NA	NA
WP_096325434.1\|438231_439351_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004204912.1\|439490_439973_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004202808.1\|440052_441891_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004200010.1\|441854_442955_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_2

542502 : 595122

Leptospira_phage(20.0%)

transposase,portal,terminase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004199890.1\|542502_543024_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0
WP_004199888.1\|543245_543743_+\|terminase	terminase	K4NXI4	Burkholderia_phage	2.6e-55	100.0
WP_004199886.1\|543739_544795_+\|portal	phage portal protein	K4NZV0	Burkholderia_phage	5.7e-206	99.4
WP_004202809.1\|544838_545195_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_004199884.1\|545197_545494_-	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	2.8e-49	98.0
WP_038802950.1\|546301_547421_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004199882.1\|548046_548319_+	flagellar biosynthesis protein FliQ	NA	NA	NA	NA
WP_004201278.1\|548437_549220_+	flagellar biosynthetic protein FliR	NA	NA	NA	NA
WP_004199881.1\|549539_549968_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004199880.1\|550049_550925_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004199879.1\|550917_551439_+	DUF2938 domain-containing protein	NA	NA	NA	NA
WP_004202867.1\|551596_552610_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004199877.1\|552693_553491_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.5e-30	35.3
WP_004201276.1\|553518_554367_+	ABC transporter permease	NA	NA	NA	NA
WP_004197153.1\|554444_555824_+	sensor histidine kinase	NA	NA	NA	NA
WP_004197150.1\|555834_556512_+	response regulator	NA	NA	NA	NA
WP_004197145.1\|556801_557962_+	porin	NA	NA	NA	NA
WP_004197141.1\|557997_558180_+	hypothetical protein	NA	NA	NA	NA
WP_024901007.1\|558434_560450_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	2.5e-85	33.8
WP_004197137.1\|560490_563520_+	DEAD/DEAH box helicase family protein	A0A2K5B256	Erysipelothrix_phage	2.2e-181	38.7
WP_004197133.1\|564057_565158_+	porin	NA	NA	NA	NA
WP_004199873.1\|565557_566517_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004538585.1\|566639_567371_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.6e-05	25.3
WP_004197129.1\|567743_568466_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.8e-07	25.5
WP_004197128.1\|568462_569512_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004197127.1\|569508_570387_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004197126.1\|570391_571651_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004198383.1\|571867_573373_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004198382.1\|573428_573821_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004198380.1\|573831_574641_-	hypothetical protein	NA	NA	NA	NA
WP_004198379.1\|574686_575484_-	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	3.3e-12	28.8
WP_004198377.1\|575568_577218_-	GMC family oxidoreductase	A0A1V0SI18	Klosneuvirus	2.0e-56	30.9
WP_004198376.1\|577945_578287_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_038802950.1\|579460_580580_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004525798.1\|581003_581309_-	hypothetical protein	NA	NA	NA	NA
WP_004202848.1\|581332_582319_-	fatty acid desaturase family protein	NA	NA	NA	NA
WP_004202847.1\|582348_583185_-	hypothetical protein	NA	NA	NA	NA
WP_160468978.1\|583643_584831_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004202842.1\|584829_585966_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004202841.1\|586572_587778_+	acetyl-CoA C-acetyltransferase	NA	NA	NA	NA
WP_004202840.1\|587790_589914_+	fatty oxidation complex subunit alpha	NA	NA	NA	NA
WP_004202838.1\|590277_591411_+	CoA transferase	NA	NA	NA	NA
WP_004525805.1\|591487_592054_-	hypothetical protein	NA	NA	NA	NA
WP_004202836.1\|592389_592845_-	hypothetical protein	NA	NA	NA	NA
WP_009935860.1\|593409_593850_+	BPSL0067 family protein	NA	NA	NA	NA
WP_004202832.1\|593836_593974_+	hypothetical protein	NA	NA	NA	NA
WP_096325434.1\|594001_595122_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_3

1212709 : 1221946

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194034.1\|1212709_1214662_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2
WP_024901038.1\|1214928_1216059_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.9e-22	27.6
WP_004194350.1\|1216092_1218099_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	9.7e-53	35.0
WP_004194137.1\|1218274_1219090_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004194274.1\|1219154_1219838_-	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.6e-05	26.0
WP_004194373.1\|1219834_1220362_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004194112.1\|1220398_1221946_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2

DBSCAN-SWA_4

1225436 : 1303382

Synechococcus_phage(15.0%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194103.1\|1225436_1226411_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_004194266.1\|1226407_1228462_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.9e-76	31.7
WP_004194375.1\|1228646_1229327_+	membrane protein	NA	NA	NA	NA
WP_004194228.1\|1229647_1230475_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_024901039.1\|1230585_1231422_-	class II glutamine amidotransferase	NA	NA	NA	NA
WP_004194323.1\|1231692_1233120_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	1.3e-54	30.4
WP_004194028.1\|1233517_1235254_-	capsular polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_004196472.1\|1235533_1236685_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_004194378.1\|1236865_1238029_+	polysaccharide export protein	NA	NA	NA	NA
WP_024901040.1\|1238110_1239658_+	capsule biosynthesis protein	NA	NA	NA	NA
WP_004194135.1\|1239664_1240447_+	ABC transporter permease	NA	NA	NA	NA
WP_004194035.1\|1240443_1241100_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.7e-11	31.1
WP_004194357.1\|1241132_1242656_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_024900377.1\|1242678_1244001_+	sulfotransferase family 2 domain-containing protein	NA	NA	NA	NA
WP_004196467.1\|1244100_1244952_+	hypothetical protein	NA	NA	NA	NA
WP_004194348.1\|1244948_1246745_+	DUF4214 domain-containing protein	NA	NA	NA	NA
WP_004541333.1\|1246762_1247698_+	hypothetical protein	NA	NA	NA	NA
WP_004194206.1\|1247694_1248537_+	sugar nucleotide-binding protein	A0A222YYW2	Synechococcus_phage	1.7e-38	35.0
WP_004194087.1\|1248546_1249560_+	GDP-mannose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	7.2e-97	52.6
WP_004194045.1\|1249575_1250616_+	dehydrogenase	A0A222YW25	Synechococcus_phage	1.7e-61	40.5
WP_004200490.1\|1250612_1251191_+	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	2.5e-17	37.2
WP_004194086.1\|1251192_1251885_+	NTP transferase domain-containing protein	A0A0G2Y8M0	Acanthamoeba_polyphaga_mimivirus	7.5e-05	28.8
WP_004194255.1\|1251881_1252451_+	HAD family hydrolase	NA	NA	NA	NA
WP_024901041.1\|1252717_1253920_+	capsular biosynthesis protein	NA	NA	NA	NA
WP_004194054.1\|1253916_1254705_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004194306.1\|1254706_1256239_+	LTA synthase family protein	NA	NA	NA	NA
WP_004202217.1\|1256241_1263882_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004194036.1\|1263878_1264796_+	UDP-3-O-acyl N-acetylglycosamine deacetylase	NA	NA	NA	NA
WP_004194209.1\|1264860_1266180_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_004194345.1\|1266188_1266881_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_038802950.1\|1267856_1268976_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_071810810.1\|1269050_1269269_+	hypothetical protein	NA	NA	NA	NA
WP_004185496.1\|1269466_1269976_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_004197486.1\|1270276_1272391_+	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_024901034.1\|1273563_1275027_+	hypothetical protein	NA	NA	NA	NA
WP_004186341.1\|1275571_1276417_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.4e-23	29.9
WP_004185897.1\|1276585_1277332_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_004197492.1\|1278047_1279409_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004522619.1\|1279381_1279717_-	DUF2917 domain-containing protein	NA	NA	NA	NA
WP_004185818.1\|1280013_1281453_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_162473466.1\|1281800_1282088_-	hypothetical protein	NA	NA	NA	NA
WP_004200476.1\|1282071_1283346_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004185918.1\|1283470_1284076_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004186428.1\|1284607_1285630_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_004185585.1\|1285645_1286173_-	DUF962 domain-containing protein	NA	NA	NA	NA
WP_004185910.1\|1286257_1287013_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_004186611.1\|1287246_1288452_+	chromate efflux transporter	NA	NA	NA	NA
WP_096325437.1\|1288540_1289661_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004185841.1\|1290723_1291302_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.1e-44	44.7
WP_004197496.1\|1291498_1292881_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	6.1e-30	27.5
WP_004200482.1\|1292875_1293106_+	hypothetical protein	NA	NA	NA	NA
WP_004555967.1\|1293338_1294367_+	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_004196455.1\|1294347_1294554_+	Trm112 family protein	NA	NA	NA	NA
WP_004185994.1\|1294727_1295519_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_004185840.1\|1295727_1296390_+	adenylate kinase	NA	NA	NA	NA
WP_004191998.1\|1296528_1297992_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196460.1\|1298095_1298299_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|1298831_1299146_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196461.1\|1299142_1301443_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1
WP_038802950.1\|1302261_1303382_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_5

1899732 : 1969847

Leptospira_phage(28.57%)

transposase,coat,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|1899732_1900852_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_073699268.1\|1900897_1901488_-	hypothetical protein	NA	NA	NA	NA
WP_004193369.1\|1901829_1902336_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	5.1e-19	39.4
WP_004191223.1\|1902332_1902758_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	1.3e-15	50.6
WP_004193964.1\|1903503_1905396_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004191686.1\|1905462_1906923_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_004197687.1\|1907145_1907523_+	hypothetical protein	NA	NA	NA	NA
WP_024901063.1\|1907546_1908125_+	flavodoxin family protein	NA	NA	NA	NA
WP_004197691.1\|1908339_1911132_-	malto-oligosyltrehalose synthase	NA	NA	NA	NA
WP_004266861.1\|1911128_1913351_-	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_004191214.1\|1913347_1915090_-	malto-oligosyltrehalose trehalohydrolase	NA	NA	NA	NA
WP_004192927.1\|1915116_1917225_-	glycogen debranching protein GlgX	NA	NA	NA	NA
WP_004205216.1\|1919486_1922882_-	maltose alpha-D-glucosyltransferase	NA	NA	NA	NA
WP_011832205.1\|1922878_1926226_-	alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase	NA	NA	NA	NA
WP_004205215.1\|1926549_1926804_+	hypothetical protein	NA	NA	NA	NA
WP_004193933.1\|1926779_1928258_-	PHB depolymerase family esterase	NA	NA	NA	NA
WP_004193830.1\|1928440_1928731_-	hypothetical protein	NA	NA	NA	NA
WP_004192837.1\|1928965_1929184_-	hypothetical protein	NA	NA	NA	NA
WP_162473508.1\|1929679_1930150_-	hypothetical protein	NA	NA	NA	NA
WP_004193316.1\|1930155_1930479_+	hypothetical protein	NA	NA	NA	NA
WP_004193478.1\|1930762_1932187_+	hypothetical protein	NA	NA	NA	NA
WP_004193589.1\|1932453_1933431_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004526732.1\|1933844_1934627_+	response regulator transcription factor	NA	NA	NA	NA
WP_004192729.1\|1934810_1935026_+	DUF3955 domain-containing protein	NA	NA	NA	NA
WP_004192564.1\|1935036_1935408_+	hypothetical protein	NA	NA	NA	NA
WP_004196675.1\|1935459_1935795_-	hypothetical protein	NA	NA	NA	NA
WP_004191937.1\|1935877_1936036_+	hypothetical protein	NA	NA	NA	NA
WP_004196677.1\|1936401_1937097_+	response regulator transcription factor	NA	NA	NA	NA
WP_004191391.1\|1937484_1940757_+	hemagglutinin	A0A2C9CZB7	Yersinia_phage	1.4e-05	33.0
WP_004191672.1\|1940837_1941548_+	OmpA family protein	NA	NA	NA	NA
WP_004192726.1\|1941549_1943079_+	hypothetical protein	D6PFH9	uncultured_phage	1.2e-15	25.4
WP_004191318.1\|1943095_1943440_+	H-NS histone family protein	NA	NA	NA	NA
WP_004193132.1\|1943862_1944105_-	hypothetical protein	NA	NA	NA	NA
WP_004193698.1\|1944150_1944711_-	SCO family protein	NA	NA	NA	NA
WP_004191878.1\|1944745_1945234_-	hypothetical protein	NA	NA	NA	NA
WP_004196681.1\|1945260_1947663_-	DUF1929 domain-containing protein	NA	NA	NA	NA
WP_004196682.1\|1947915_1948149_-	hypothetical protein	NA	NA	NA	NA
WP_004266855.1\|1948193_1949030_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_009966472.1\|1949199_1949328_-	hypothetical protein	NA	NA	NA	NA
WP_004192127.1\|1950321_1952172_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004193292.1\|1952199_1953615_-	hypothetical protein	NA	NA	NA	NA
WP_004193592.1\|1953638_1953905_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_004192367.1\|1954164_1954392_-	hypothetical protein	NA	NA	NA	NA
WP_004191109.1\|1954425_1957233_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	6.8e-28	25.1
WP_004192570.1\|1957235_1958069_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_038802950.1\|1958302_1959423_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004193170.1\|1960158_1961472_+	divalent metal cation transporter	NA	NA	NA	NA
WP_004191144.1\|1962366_1962636_+	hypothetical protein	NA	NA	NA	NA
WP_004193855.1\|1962888_1963170_-	H-NS histone family protein	NA	NA	NA	NA
WP_004192394.1\|1963637_1964630_-	amidohydrolase family protein	NA	NA	NA	NA
WP_004196700.1\|1964674_1965871_-	MFS transporter	NA	NA	NA	NA
WP_004196705.1\|1966377_1967271_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004531175.1\|1967608_1967830_+	hypothetical protein	NA	NA	NA	NA
WP_004542449.1\|1967915_1968101_+	hypothetical protein	NA	NA	NA	NA
WP_004192149.1\|1968087_1968633_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191870.1\|1968685_1969246_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526783.1\|1969322_1969847_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_6

2032950 : 2102907

Bacillus_phage(15.38%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191922.1\|2032950_2035818_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.8e-146	39.3
WP_004192721.1\|2035957_2038321_+	UvrD-helicase domain-containing protein	S5M596	Bacillus_phage	4.2e-71	30.6
WP_004193777.1\|2038317_2039106_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_004192717.1\|2039426_2040677_-	MFS transporter	NA	NA	NA	NA
WP_004196082.1\|2041028_2042705_+	chemotaxis methyl-accepting membrane protein	A0A2H4J162	uncultured_Caudovirales_phage	3.9e-15	31.2
WP_004191342.1\|2043052_2043934_-	HlyD family secretion protein	NA	NA	NA	NA
WP_004191885.1\|2043947_2044151_-	DUF1656 domain-containing protein	NA	NA	NA	NA
WP_004192976.1\|2044147_2046349_-	FUSC family protein	NA	NA	NA	NA
WP_024900385.1\|2046365_2048132_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004191155.1\|2048304_2049246_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004192873.1\|2049589_2050573_-	ser/threonine protein phosphatase	S4VP02	Pandoravirus	1.8e-20	34.0
WP_004193704.1\|2051240_2051849_-	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_004266851.1\|2051954_2053265_+	YihY family inner membrane protein	NA	NA	NA	NA
WP_004192500.1\|2053436_2053757_-	DUF962 domain-containing protein	NA	NA	NA	NA
WP_004193328.1\|2053973_2054438_+	CBS domain-containing protein	NA	NA	NA	NA
WP_004196088.1\|2054537_2056352_+	MFS transporter	NA	NA	NA	NA
WP_125754530.1\|2056363_2056468_+	MFS transporter	NA	NA	NA	NA
WP_004266572.1\|2056832_2057942_+	chorismate synthase	A0A291AU41	Pandoravirus	1.1e-82	43.7
WP_004521230.1\|2058107_2058641_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_024900959.1\|2058640_2059054_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.8e-29	52.0
WP_038802950.1\|2059098_2060219_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197788.1\|2060306_2061482_+	carbamoyltransferase	E3SL71	Synechococcus_phage	1.8e-46	35.9
WP_004192661.1\|2061606_2063979_+	penicillin acylase family protein	NA	NA	NA	NA
WP_162473478.1\|2064147_2064396_+	hypothetical protein	NA	NA	NA	NA
WP_011857895.1\|2065401_2066952_+	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_004192734.1\|2067001_2068267_+	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_011203914.1\|2068417_2070097_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_004193599.1\|2070340_2070802_+	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_004191720.1\|2071038_2071449_-\|transposase	transposase	NA	NA	NA	NA
WP_004550551.1\|2071643_2072741_-	cell division protein ZapE	NA	NA	NA	NA
WP_004191219.1\|2072847_2074278_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-42	27.8
WP_004192735.1\|2074377_2075652_-	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_004191889.1\|2075779_2078644_-	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_004193111.1\|2078982_2080809_-	translational GTPase TypA	NA	NA	NA	NA
WP_004191941.1\|2080761_2080902_+	hypothetical protein	NA	NA	NA	NA
WP_004192835.1\|2081101_2081599_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004191557.1\|2081698_2083195_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004192058.1\|2083262_2084498_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004193982.1\|2084520_2086080_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_011203915.1\|2086350_2087286_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_004199441.1\|2087312_2087681_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_004197388.1\|2087786_2090714_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.2e-23	25.3
WP_004193517.1\|2090805_2092281_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_004193908.1\|2092277_2092739_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_004191876.1\|2093043_2094708_-	pseudouridine synthase	NA	NA	NA	NA
WP_004192767.1\|2094771_2096100_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	5.3e-23	35.1
WP_004193481.1\|2096518_2097421_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.5e-10	23.6
WP_004199443.1\|2097839_2098241_+\|transposase	transposase	NA	NA	NA	NA
WP_004521676.1\|2098446_2098704_+	hypothetical protein	NA	NA	NA	NA
WP_004199444.1\|2098862_2099180_-	hypothetical protein	NA	NA	NA	NA
WP_004192638.1\|2099380_2100103_+	YdcF family protein	NA	NA	NA	NA
WP_004192834.1\|2100341_2100620_+	hypothetical protein	NA	NA	NA	NA
WP_004191628.1\|2100768_2101026_+	hypothetical protein	NA	NA	NA	NA
WP_004193694.1\|2101075_2101366_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2101787_2102907_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_7

2782791 : 2862044

Streptococcus_phage(28.57%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004192783.1\|2782791_2784318_+\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	2.8e-84	35.6
WP_004193508.1\|2784685_2785411_+	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_004192531.1\|2785824_2786034_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_004193872.1\|2786052_2786394_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_004193590.1\|2786486_2788355_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	7.3e-103	41.7
WP_004202016.1\|2788420_2788948_-	Fe-S protein assembly co-chaperone HscB	NA	NA	NA	NA
WP_004191333.1\|2789060_2789384_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	8.9e-25	51.4
WP_004192918.1\|2789466_2789874_-	Fe-S cluster assembly scaffold IscU	A0A2H4N7M4	Lake_Baikal_phage	1.2e-50	78.0
WP_004192952.1\|2789939_2791163_-	IscS subfamily cysteine desulfurase	NA	NA	NA	NA
WP_004195928.1\|2791231_2791771_-	Fe-S cluster assembly transcriptional regulator IscR	NA	NA	NA	NA
WP_004557108.1\|2791872_2792352_-	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_004193107.1\|2792443_2792653_-	hypothetical protein	NA	NA	NA	NA
WP_004191338.1\|2792814_2794266_-	lactate utilization protein	NA	NA	NA	NA
WP_004193278.1\|2794414_2795137_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004191360.1\|2795319_2796132_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_004191998.1\|2796260_2797724_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004199567.1\|2797832_2798402_-	phasin family protein	NA	NA	NA	NA
WP_004191998.1\|2800311_2801775_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192702.1\|2802031_2803801_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	6.8e-34	23.8
WP_004193075.1\|2804108_2805698_-	dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_004199569.1\|2805830_2808527_-	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_004192045.1\|2808658_2808880_-	hypothetical protein	NA	NA	NA	NA
WP_004557112.1\|2808799_2811310_+	PAS domain S-box protein	NA	NA	NA	NA
WP_004193928.1\|2811306_2811945_+	response regulator transcription factor	NA	NA	NA	NA
WP_004192825.1\|2812261_2813119_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	4.1e-37	39.9
WP_004199570.1\|2813075_2813291_-	hypothetical protein	NA	NA	NA	NA
WP_004191126.1\|2813804_2815904_+	M3 family metallopeptidase	A0A1V0SD92	Indivirus	1.7e-39	21.8
WP_004191702.1\|2816133_2817336_-	DNA polymerase IV	NA	NA	NA	NA
WP_004192547.1\|2817288_2817573_+	hypothetical protein	NA	NA	NA	NA
WP_004193983.1\|2818058_2819339_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_004192248.1\|2819382_2820768_+	NarK family nitrate/nitrite MFS transporter	NA	NA	NA	NA
WP_004193149.1\|2821018_2824744_+	nitrate reductase subunit alpha	NA	NA	NA	NA
WP_004193619.1\|2824740_2826294_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	2.9e-20	46.5
WP_004192818.1\|2826290_2826995_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_004191967.1\|2827031_2827718_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_004193869.1\|2827859_2829782_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_004192421.1\|2829817_2830519_+	response regulator	NA	NA	NA	NA
WP_004193531.1\|2830665_2831442_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_004191998.1\|2831724_2833188_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192209.1\|2833321_2834857_-	nitrogen regulation protein NR(I)	NA	NA	NA	NA
WP_004192981.1\|2834894_2836037_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004192601.1\|2836203_2837619_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_004191860.1\|2838023_2838488_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_004192990.1\|2838740_2839559_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_004193555.1\|2839555_2840389_-	EI24 domain-containing protein	NA	NA	NA	NA
WP_004192998.1\|2840932_2841922_-	sterol desaturase family protein	NA	NA	NA	NA
WP_004192001.1\|2841938_2842931_-	beta-propeller fold lactonase family protein	A0A2H4JCI3	uncultured_Caudovirales_phage	3.5e-11	59.6
WP_004192168.1\|2847182_2848559_+	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_004193961.1\|2848611_2848887_+	oxidative damage protection protein	NA	NA	NA	NA
WP_004192533.1\|2849059_2850391_-	MHS family MFS transporter	NA	NA	NA	NA
WP_004199573.1\|2850599_2852126_-	CoA transferase	NA	NA	NA	NA
WP_004193195.1\|2852122_2853916_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004193679.1\|2854024_2854927_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004191998.1\|2855328_2856792_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_011832359.1\|2856908_2857475_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2857618_2858739_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004193468.1\|2858848_2859325_-	hypothetical protein	NA	NA	NA	NA
WP_004200110.1\|2859781_2860006_+	hypothetical protein	NA	NA	NA	NA
WP_004193210.1\|2860270_2861407_+	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_004522511.1\|2861504_2862044_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA

DBSCAN-SWA_8

3173689 : 3237596

Leptospira_phage(25.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004192020.1\|3173689_3175198_-\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	2.8e-20	27.7
WP_004192760.1\|3175214_3176267_-	sugar dehydratase	NA	NA	NA	NA
WP_004192486.1\|3176272_3176875_-	sigma-E factor negative regulatory protein	NA	NA	NA	NA
WP_004193971.1\|3176958_3177558_-	RNA polymerase sigma factor RpoE	A0A0F6TH34	Sinorhizobium_phage	3.8e-05	27.3
WP_004192146.1\|3177663_3178137_-	hypothetical protein	NA	NA	NA	NA
WP_024901020.1\|3178148_3179387_-	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_004197638.1\|3179543_3179783_-	acyl carrier protein	B2ZXV3	Ralstonia_phage	1.6e-10	47.1
WP_004197597.1\|3179926_3180676_-	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	5.8e-19	30.9
WP_004193828.1\|3180726_3181659_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_004191537.1\|3181729_3182719_-	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_004192749.1\|3182718_3183825_-	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_004192741.1\|3183963_3184143_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_004193919.1\|3184239_3184872_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_004192535.1\|3185115_3185763_+	septum formation protein Maf	NA	NA	NA	NA
WP_004193677.1\|3185759_3186482_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004191725.1\|3186520_3187522_-	S49 family peptidase	NA	NA	NA	NA
WP_004193415.1\|3187531_3187927_-	Rieske 2Fe-2S domain-containing protein	NA	NA	NA	NA
WP_004193798.1\|3188224_3189232_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_004192715.1\|3189995_3193268_+	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_004532083.1\|3193407_3194520_+	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_004192903.1\|3194553_3195177_+	molybdenum cofactor guanylyltransferase MobA	NA	NA	NA	NA
WP_004191191.1\|3195288_3196599_+	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_004192965.1\|3196635_3196923_+	hypothetical protein	NA	NA	NA	NA
WP_004199373.1\|3196919_3197423_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004193862.1\|3197665_3199141_-	DNA recombination protein RmuC	NA	NA	NA	NA
WP_011203830.1\|3199137_3200127_-	D-glycerate dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	4.1e-12	25.8
WP_004193636.1\|3200192_3201635_-	sodium:proton antiporter	NA	NA	NA	NA
WP_004192015.1\|3201690_3202353_-	lactate utilization protein C	NA	NA	NA	NA
WP_004202995.1\|3202497_3203697_-	nicotinate phosphoribosyltransferase	A0A2L0UZQ6	Agrobacterium_phage	1.2e-55	34.7
WP_004193394.1\|3203781_3204048_+	hypothetical protein	NA	NA	NA	NA
WP_004205776.1\|3203965_3204289_+	ferredoxin family protein	NA	NA	NA	NA
WP_004197812.1\|3204776_3205256_+	protein CreA	NA	NA	NA	NA
WP_004536352.1\|3205846_3206635_+	DUF4088 family protein	NA	NA	NA	NA
WP_004189585.1\|3206819_3207326_-	hypothetical protein	NA	NA	NA	NA
WP_004189709.1\|3207663_3207885_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_004189199.1\|3208009_3209416_+	MATE family efflux transporter	NA	NA	NA	NA
WP_038802950.1\|3209733_3210853_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197806.1\|3211049_3211223_-	hypothetical protein	NA	NA	NA	NA
WP_004189867.1\|3211237_3212632_+	class II fumarate hydratase	NA	NA	NA	NA
WP_004190145.1\|3213110_3213617_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_162473585.1\|3213804_3214011_-	hypothetical protein	NA	NA	NA	NA
WP_004189917.1\|3214562_3215273_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004191998.1\|3218111_3219575_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189292.1\|3219732_3221343_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_004189626.1\|3221355_3221538_+	hypothetical protein	NA	NA	NA	NA
WP_004189552.1\|3221510_3222770_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189780.1\|3223037_3223616_+	pseudouridine synthase	NA	NA	NA	NA
WP_096325434.1\|3223809_3224930_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_096325434.1\|3226041_3227162_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197797.1\|3227588_3227747_+	glycosyl transferase family 2	NA	NA	NA	NA
WP_011203825.1\|3227743_3228337_-	chorismate mutase	NA	NA	NA	NA
WP_004189159.1\|3228949_3229339_+	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_004188913.1\|3229485_3231822_+	TonB-dependent receptor	NA	NA	NA	NA
WP_004189437.1\|3231830_3233081_+	exo-alpha-sialidase	NA	NA	NA	NA
WP_004203540.1\|3233077_3233566_+	hypothetical protein	NA	NA	NA	NA
WP_004197795.1\|3233852_3234104_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_004197793.1\|3234803_3235019_+	hypothetical protein	NA	NA	NA	NA
WP_004197792.1\|3235274_3235751_-	hypothetical protein	NA	NA	NA	NA
WP_004190100.1\|3235773_3236034_-	hypothetical protein	NA	NA	NA	NA
WP_004187628.1\|3236375_3237596_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5

DBSCAN-SWA_9

3290473 : 3299315

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004189214.1\|3290473_3291874_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-78	38.3
WP_004200795.1\|3291842_3292829_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	8.8e-15	26.5
WP_004190173.1\|3292887_3293880_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004189725.1\|3293951_3294269_+	competence protein ComE	NA	NA	NA	NA
WP_004532363.1\|3294592_3295495_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_024901052.1\|3295720_3297028_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004188957.1\|3297206_3298130_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_004190087.1\|3298472_3299315_-	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.2

DBSCAN-SWA_10

3560453 : 3617978

Vibrio_phage(17.65%)

transposase,protease,portal,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|3560453_3561917_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004190029.1\|3562083_3562854_-	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	3.4e-30	33.8
WP_004189747.1\|3562885_3563725_-	hypothetical protein	NA	NA	NA	NA
WP_004190092.1\|3563851_3565324_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_004189326.1\|3565326_3566817_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_004189769.1\|3566929_3567229_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_024901104.1\|3567594_3568638_+	rod shape-determining protein	NA	NA	NA	NA
WP_004189331.1\|3568757_3569831_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004189260.1\|3569827_3570340_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004189575.1\|3570523_3572932_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_004189171.1\|3572943_3574092_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_004190168.1\|3574442_3575219_-	sel1 repeat family protein	NA	NA	NA	NA
WP_004189570.1\|3575215_3576001_-	2-dehydro-3-deoxyglucarate aldolase	NA	NA	NA	NA
WP_004189793.1\|3576422_3576875_-	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8
WP_004189241.1\|3576894_3577527_-	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004190026.1\|3577620_3578355_-	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189647.1\|3578822_3579506_-	response regulator	NA	NA	NA	NA
WP_004189034.1\|3579506_3581915_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004188929.1\|3581916_3582507_-	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_004189046.1\|3582503_3583913_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004189409.1\|3584282_3585140_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004189288.1\|3585249_3585885_-	LysE family translocator	NA	NA	NA	NA
WP_004200737.1\|3586005_3586989_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004201745.1\|3587020_3587524_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.7e-12	34.3
WP_004190020.1\|3587752_3588943_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004190199.1\|3589002_3589374_+	thioredoxin family protein	NA	NA	NA	NA
WP_004200734.1\|3589584_3592194_+	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004189230.1\|3592415_3593471_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004188904.1\|3593920_3594937_+	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004189208.1\|3595057_3595927_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004200732.1\|3595964_3596369_-	PaaI family thioesterase	NA	NA	NA	NA
WP_004187628.1\|3596759_3597980_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5
WP_038802950.1\|3599296_3600416_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200731.1\|3600468_3600951_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_004188977.1\|3600947_3601232_+	hypothetical protein	NA	NA	NA	NA
WP_004200730.1\|3601304_3602396_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	2.0e-193	92.3
WP_004200729.1\|3602794_3603205_+	hypothetical protein	NA	NA	NA	NA
WP_004189258.1\|3603341_3604217_-	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	9.6e-74	47.3
WP_004190014.1\|3604227_3605340_-	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.2e-37	30.8
WP_004201742.1\|3605368_3606463_-	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004189434.1\|3606605_3607574_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004189874.1\|3607676_3608246_+	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004189689.1\|3608838_3609387_+	hypothetical protein	NA	NA	NA	NA
WP_004189592.1\|3609650_3611099_+	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	4.9e-30	33.5
WP_004200727.1\|3611117_3612731_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_004200726.1\|3612890_3613832_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004190110.1\|3613828_3614923_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.8e-19	37.4
WP_004197761.1\|3615324_3615741_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_004197759.1\|3615926_3616481_-	YaeQ family protein	NA	NA	NA	NA
WP_038802950.1\|3616858_3617978_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP010349

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP010348

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection