CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP017377	Staphylococcus aureus strain OC8	9 crisprs	cas3,csa3,DEDDh,DinG,WYL	11	2	13	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP017377_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_1

414962-415062

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP017377_1

>merge|NZ_AP017377|1|414962-415062|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NZ_AP017377|1|1|414962-415062|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_000868248.1\|407568_407952_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_001789518.1\|414186_414288_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000041883.1\|423835_424540_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_AP017377.1\|WP_000264071.1\|419761_421228_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_AP017377.1\|WP_024937135.1\|409277_410801_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_AP017377.1\|WP_000551776.1\|422906_423443_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000421410.1\|417877_418456_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_AP017377.1\|WP_000158374.1\|406921_407503_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_AP017377.1\|WP_000159787.1\|424938_425211_-\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_AP017377.1\|WP_000466748.1\|406244_406496_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_AP017377.1\|WP_000991007.1\|412713_414102_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_AP017377.1\|WP_001289311.1\|411877_412633_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NZ_AP017377.1\|WP_000746687.1\|408206_408833_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_AP017377.1\|WP_000956132.1\|415078_416035_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NZ_AP017377.1\|WP_000211676.1\|406534_406744_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000793009.1\|418455_419724_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_AP017377.1\|WP_000424966.1\|421252_422794_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_AP017377.1\|WP_000763768.1\|416957_417365_-\|general-stress-protein	unknown	unknown	gnl\|CDD\|378584
NZ_AP017377.1\|WP_000052781.1\|410816_411386_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_AP017377.1\|WP_000394698.1\|416152_416815_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_000421410.1\|417877_418456_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
NZ_AP017377.1\|WP_000041883.1\|423835_424540_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	9.65175e-08
NZ_AP017377.1\|WP_000264071.1\|419761_421228_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_AP017377.1\|WP_024937135.1\|409277_410801_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_AP017377.1\|WP_000158374.1\|406921_407503_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49
NZ_AP017377.1\|WP_000159787.1\|424938_425211_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
NZ_AP017377.1\|WP_000466748.1\|406244_406496_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
NZ_AP017377.1\|WP_000991007.1\|412713_414102_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_AP017377.1\|WP_001289311.1\|411877_412633_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
NZ_AP017377.1\|WP_000746687.1\|408206_408833_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
NZ_AP017377.1\|WP_000956132.1\|415078_416035_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
NZ_AP017377.1\|WP_000793009.1\|418455_419724_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
NZ_AP017377.1\|WP_000424966.1\|421252_422794_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_AP017377.1\|WP_000763768.1\|416957_417365_-\|general-stress-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
NZ_AP017377.1\|WP_000052781.1\|410816_411386_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124

>NZ_AP017377.1|WP_001789518.1|414186_414288_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNSVVIGGKGK
>NZ_AP017377.1|WP_000991007.1|412713_414102_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>NZ_AP017377.1|WP_001289311.1|411877_412633_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_AP017377.1|WP_000052781.1|410816_411386_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_AP017377.1|WP_024937135.1|409277_410801_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDESIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_AP017377.1|WP_000746687.1|408206_408833_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_AP017377.1|WP_000868248.1|407568_407952_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>NZ_AP017377.1|WP_000158374.1|406921_407503_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>NZ_AP017377.1|WP_000211676.1|406534_406744_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFNPILSTFSNIIIHIDHFHANKKDDN
>NZ_AP017377.1|WP_000466748.1|406244_406496_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>NZ_AP017377.1|WP_000956132.1|415078_416035_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_AP017377.1|WP_000394698.1|416152_416815_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_AP017377.1|WP_000763768.1|416957_417365_-|general-stress-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>NZ_AP017377.1|WP_000421410.1|417877_418456_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NZ_AP017377.1|WP_000793009.1|418455_419724_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_AP017377.1|WP_000264071.1|419761_421228_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_AP017377.1|WP_000424966.1|421252_422794_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_AP017377.1|WP_000551776.1|422906_423443_-|hypothetical-protein
MHNNNEFNKKLKDFIGSDKRMALVKGYVNEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNTIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>NZ_AP017377.1|WP_000041883.1|423835_424540_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSYSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALAQKYREIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>NZ_AP017377.1|WP_000159787.1|424938_425211_-|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

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Click the colored protein region to show detailed information

Crispr_ID: NZ_AP017377_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_2

661961-662053

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP017377_2

>merge|NZ_AP017377|2|661961-662053|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>NZ_AP017377|2|2|661961-662053|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_000655099.1\|658444_658552_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000169042.1\|670838_671063_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_AP017377.1\|WP_000365354.1\|664161_664881_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_AP017377.1\|WP_000735558.1\|665800_666307_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_001200748.1\|657359_658370_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_AP017377.1\|WP_000362967.1\|664864_665665_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_AP017377.1\|WP_000180230.1\|655028_656324_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_AP017377.1\|WP_001790232.1\|663156_664107_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_AP017377.1\|WP_001018677.1\|668392_668767_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_AP017377.1\|WP_000808902.1\|652658_653597_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_AP017377.1\|WP_001788287.1\|656351_656873_+\|YwhD-family-protein	unknown	unknown	gnl\|CDD\|378039
NZ_AP017377.1\|WP_000749059.1\|662121_663009_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_AP017377.1\|WP_001021145.1\|659057_660719_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_AP017377.1\|WP_001045421.1\|667353_668142_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_AP017377.1\|WP_000359086.1\|658644_659061_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
NZ_AP017377.1\|WP_000901764.1\|661107_661743_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_AP017377.1\|WP_000477504.1\|654512_654989_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP017377.1\|WP_001553862.1\|669714_670644_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_AP017377.1\|WP_000633782.1\|653807_654344_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_AP017377.1\|WP_001222133.1\|666468_667185_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_000169042.1\|670838_671063_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
NZ_AP017377.1\|WP_000365354.1\|664161_664881_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_AP017377.1\|WP_001200748.1\|657359_658370_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_AP017377.1\|WP_000362967.1\|664864_665665_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
NZ_AP017377.1\|WP_000180230.1\|655028_656324_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_AP017377.1\|WP_001790232.1\|663156_664107_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NZ_AP017377.1\|WP_001018677.1\|668392_668767_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NZ_AP017377.1\|WP_000808902.1\|652658_653597_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NZ_AP017377.1\|WP_001021145.1\|659057_660719_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_AP017377.1\|WP_000749059.1\|662121_663009_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
NZ_AP017377.1\|WP_001045421.1\|667353_668142_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
NZ_AP017377.1\|WP_001553862.1\|669714_670644_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37
NZ_AP017377.1\|WP_000359086.1\|658644_659061_+\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58
NZ_AP017377.1\|WP_000901764.1\|661107_661743_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NZ_AP017377.1\|WP_000477504.1\|654512_654989_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_AP017377.1\|WP_001788287.1\|656351_656873_+\|YwhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_AP017377.1\|WP_000633782.1\|653807_654344_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26

>NZ_AP017377.1|WP_000901764.1|661107_661743_+|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_AP017377.1|WP_001021145.1|659057_660719_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_AP017377.1|WP_000359086.1|658644_659061_+|DUF1934-domain-containing-protein
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_AP017377.1|WP_000655099.1|658444_658552_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NZ_AP017377.1|WP_001200748.1|657359_658370_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_AP017377.1|WP_001788287.1|656351_656873_+|YwhD-family-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_AP017377.1|WP_000180230.1|655028_656324_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_AP017377.1|WP_000477504.1|654512_654989_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_AP017377.1|WP_000633782.1|653807_654344_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_AP017377.1|WP_000808902.1|652658_653597_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>NZ_AP017377.1|WP_000749059.1|662121_663009_+|ABC-transporter-substrate-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_AP017377.1|WP_001790232.1|663156_664107_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_AP017377.1|WP_000365354.1|664161_664881_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_AP017377.1|WP_000362967.1|664864_665665_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_AP017377.1|WP_000735558.1|665800_666307_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_AP017377.1|WP_001222133.1|666468_667185_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_AP017377.1|WP_001045421.1|667353_668142_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>NZ_AP017377.1|WP_001018677.1|668392_668767_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_AP017377.1|WP_001553862.1|669714_670644_-|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_AP017377.1|WP_000169042.1|670838_671063_-|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

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Crispr_ID: NZ_AP017377_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_3

779309-779391

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP017377_3

>merge|NZ_AP017377|3|779309-779391|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGTCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>NZ_AP017377|3|3|779309-779391|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGTCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_000499195.1\|789128_789284_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_001790641.1\|780847_780949_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000525109.1\|770586_772470_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_AP017377.1\|WP_000855505.1\|785420_787526_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_AP017377.1\|WP_000022323.1\|766897_767902_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NZ_AP017377.1\|WP_000180991.1\|775454_776969_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_AP017377.1\|WP_000663030.1\|777208_778267_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NZ_AP017377.1\|WP_000876318.1\|789322_790294_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NZ_AP017377.1\|WP_000983677.1\|772481_774263_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NZ_AP017377.1\|WP_000193751.1\|781026_782532_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_AP017377.1\|WP_000562498.1\|787643_788615_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_AP017377.1\|WP_000589260.1\|774484_775462_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_AP017377.1\|WP_000098285.1\|768375_770316_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NZ_AP017377.1\|WP_000930014.1\|782872_783373_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NZ_AP017377.1\|WP_000692521.1\|785059_785458_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NZ_AP017377.1\|WP_001790169.1\|765909_766116_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000429014.1\|779839_780757_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_AP017377.1\|WP_000197271.1\|778617_779160_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NZ_AP017377.1\|WP_000708692.1\|766203_766914_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NZ_AP017377.1\|WP_001068497.1\|783392_784259_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_000562498.1\|787643_788615_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NZ_AP017377.1\|WP_000525109.1\|770586_772470_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_AP017377.1\|WP_000855505.1\|785420_787526_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_AP017377.1\|WP_000022323.1\|766897_767902_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
NZ_AP017377.1\|WP_000180991.1\|775454_776969_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
NZ_AP017377.1\|WP_000663030.1\|777208_778267_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NZ_AP017377.1\|WP_000876318.1\|789322_790294_+\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
NZ_AP017377.1\|WP_000983677.1\|772481_774263_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_AP017377.1\|WP_000193751.1\|781026_782532_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NZ_AP017377.1\|WP_000589260.1\|774484_775462_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.80291e-155
NZ_AP017377.1\|WP_000098285.1\|768375_770316_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_AP017377.1\|WP_000930014.1\|782872_783373_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
NZ_AP017377.1\|WP_000692521.1\|785059_785458_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NZ_AP017377.1\|WP_000429014.1\|779839_780757_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	3.10512e-78
NZ_AP017377.1\|WP_000197271.1\|778617_779160_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	1.15481e-107
NZ_AP017377.1\|WP_000708692.1\|766203_766914_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.29969e-94
NZ_AP017377.1\|WP_001068497.1\|783392_784259_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.8323e-10

>NZ_AP017377.1|WP_000197271.1|778617_779160_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPYAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NZ_AP017377.1|WP_000663030.1|777208_778267_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NZ_AP017377.1|WP_000180991.1|775454_776969_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NZ_AP017377.1|WP_000589260.1|774484_775462_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQLLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NZ_AP017377.1|WP_000983677.1|772481_774263_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NZ_AP017377.1|WP_000525109.1|770586_772470_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMMDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREENEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NZ_AP017377.1|WP_000098285.1|768375_770316_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NZ_AP017377.1|WP_000022323.1|766897_767902_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NZ_AP017377.1|WP_000708692.1|766203_766914_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NZ_AP017377.1|WP_001790169.1|765909_766116_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NZ_AP017377.1|WP_000429014.1|779839_780757_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NZ_AP017377.1|WP_001790641.1|780847_780949_+|hypothetical-protein
MVINEIDFYRVGRENIVIAVYNEHIKFLFILIS
>NZ_AP017377.1|WP_000193751.1|781026_782532_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NZ_AP017377.1|WP_000930014.1|782872_783373_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NZ_AP017377.1|WP_001068497.1|783392_784259_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NZ_AP017377.1|WP_000692521.1|785059_785458_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NZ_AP017377.1|WP_000855505.1|785420_787526_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NZ_AP017377.1|WP_000562498.1|787643_788615_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NZ_AP017377.1|WP_000499195.1|789128_789284_+|hypothetical-protein
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NZ_AP017377.1|WP_000876318.1|789322_790294_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

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Crispr_ID: NZ_AP017377_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_4

869198-869279

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP017377_4

>merge|NZ_AP017377|4|869198-869279|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_AP017377|4|4|869198-869279|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_000752917.1\|873666_873861_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_AP017377.1\|WP_000589549.1\|867142_867499_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_AP017377.1\|WP_000974460.1\|864620_865043_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_AP017377.1\|WP_000290485.1\|867656_868037_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_AP017377.1\|WP_000205572.1\|876131_877439_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_AP017377.1\|WP_000150017.1\|865190_865907_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_AP017377.1\|WP_001018962.1\|869835_870222_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_AP017377.1\|WP_000520233.1\|871778_872474_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_AP017377.1\|WP_001140686.1\|862301_862883_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_AP017377.1\|WP_001190695.1\|866678_866999_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_AP017377.1\|WP_000732326.1\|872491_873313_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_AP017377.1\|WP_000168845.1\|875272_876034_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_AP017377.1\|WP_000422909.1\|865989_866529_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_AP017377.1\|WP_001065801.1\|870214_870511_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_AP017377.1\|WP_000255561.1\|862955_863573_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_AP017377.1\|WP_001006454.1\|877544_878795_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_AP017377.1\|WP_001183858.1\|874093_874945_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_AP017377.1\|WP_000569884.1\|863727_864222_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_AP017377.1\|WP_000932216.1\|868215_869094_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_AP017377.1\|WP_000571218.1\|870760_871786_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_000752917.1\|873666_873861_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_AP017377.1\|WP_000589549.1\|867142_867499_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_AP017377.1\|WP_000974460.1\|864620_865043_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_AP017377.1\|WP_000290485.1\|867656_868037_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.81086e-68
NZ_AP017377.1\|WP_000205572.1\|876131_877439_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	8.11734e-136
NZ_AP017377.1\|WP_000150017.1\|865190_865907_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.26721e-148
NZ_AP017377.1\|WP_001018962.1\|869835_870222_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_AP017377.1\|WP_000520233.1\|871778_872474_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_AP017377.1\|WP_001140686.1\|862301_862883_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.48911e-47
NZ_AP017377.1\|WP_001190695.1\|866678_866999_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_AP017377.1\|WP_000732326.1\|872491_873313_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_AP017377.1\|WP_000168845.1\|875272_876034_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_AP017377.1\|WP_000422909.1\|865989_866529_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.47647e-49
NZ_AP017377.1\|WP_001065801.1\|870214_870511_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_AP017377.1\|WP_000255561.1\|862955_863573_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	9.12336e-62
NZ_AP017377.1\|WP_001006454.1\|877544_878795_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_AP017377.1\|WP_001183858.1\|874093_874945_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76
NZ_AP017377.1\|WP_000569884.1\|863727_864222_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_AP017377.1\|WP_000932216.1\|868215_869094_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.16579e-75
NZ_AP017377.1\|WP_000571218.1\|870760_871786_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170

>NZ_AP017377.1|WP_000932216.1|868215_869094_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_AP017377.1|WP_000290485.1|867656_868037_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NZ_AP017377.1|WP_000589549.1|867142_867499_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_AP017377.1|WP_001190695.1|866678_866999_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_AP017377.1|WP_000422909.1|865989_866529_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEGDMPKAPRKNRNLITLY
>NZ_AP017377.1|WP_000150017.1|865190_865907_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGVPQAPGQIDVTDLKAQVTLY
>NZ_AP017377.1|WP_000974460.1|864620_865043_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_AP017377.1|WP_000569884.1|863727_864222_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_AP017377.1|WP_000255561.1|862955_863573_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGETQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>NZ_AP017377.1|WP_001140686.1|862301_862883_+|histidine-phosphatase-family-protein
MAKTLYIMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NZ_AP017377.1|WP_001018962.1|869835_870222_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_AP017377.1|WP_001065801.1|870214_870511_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_AP017377.1|WP_000571218.1|870760_871786_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_AP017377.1|WP_000520233.1|871778_872474_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_AP017377.1|WP_000732326.1|872491_873313_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_AP017377.1|WP_000752917.1|873666_873861_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_AP017377.1|WP_001183858.1|874093_874945_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_AP017377.1|WP_000168845.1|875272_876034_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_AP017377.1|WP_000205572.1|876131_877439_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_AP017377.1|WP_001006454.1|877544_878795_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF

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Crispr_ID: NZ_AP017377_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_5

975898-976107

Orphan

Consensus_repeat	Method
TCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATTNNN	CRT

3 spacers

The CRISPR arrays of NZ_AP017377_5

>merge|NZ_AP017377|5|975898-976107|CRT
TCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATTGAAAGCTGACTATTGGCCAGCTTCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATT

>NZ_AP017377|5|1|975898-976107|CRT
TCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATT	GAAAGCTGACTATTGGCCAGCT
TCTGTGTTGGGGCCCCGCCAACTTGCATTGTCTGTAG	AATTTCTTTTCGAAATTC
TCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATT	GAAAGCTGACTATTGGCCAGCT
TCTGTGTTGGGGCCCTTACCCCAACTTGCACATTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_001217125.1\|974459_975155_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_AP017377.1\|WP_000434765.1\|979268_980060_+\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|223584
NZ_AP017377.1\|WP_000004335.1\|972801_974463_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_AP017377.1\|WP_000163826.1\|982155_982467_-\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|227871
NZ_AP017377.1\|WP_001549041.1\|961373_963791_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_AP017377.1\|WP_000526539.1\|958841_959795_-\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
NZ_AP017377.1\|WP_001024576.1\|982553_983630_+\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NZ_AP017377.1\|WP_024937151.1\|980074_980719_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_AP017377.1\|WP_000265417.1\|976457_977867_+\|Mn(2+)-dependent-dipeptidase-Sapep	unknown	unknown	gnl\|CDD\|235988
NZ_AP017377.1\|WP_000411085.1\|977870_978719_+\|D-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|130191
NZ_AP017377.1\|WP_000811163.1\|983694_984006_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_AP017377.1\|WP_000689580.1\|981188_982031_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293814
NZ_AP017377.1\|WP_001050548.1\|964449_971010_+\|LPXTG-anchored-repetitive-surface-protein-SasC	unknown	unknown	gnl\|CDD\|275089
NZ_AP017377.1\|WP_001048369.1\|984991_985588_+\|DUF4479-domain-containing-protein	unknown	unknown	gnl\|CDD\|234804
NZ_AP017377.1\|WP_000836465.1\|963812_964124_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_AP017377.1\|WP_001025061.1\|959904_961086_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_AP017377.1\|WP_001091387.1\|984105_984963_+\|DUF1444-domain-containing-protein	unknown	unknown	gnl\|CDD\|237463
NZ_AP017377.1\|WP_001051860.1\|975171_975594_+\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|378938
NZ_AP017377.1\|WP_000764419.1\|958281_958845_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|377744
NZ_AP017377.1\|WP_000285019.1\|971126_972395_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|367519

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_001217125.1\|974459_975155_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	2.1062e-94
NZ_AP017377.1\|WP_000434765.1\|979268_980060_+\|phosphotransferase-family-protein	gnl\|CDD\|223584	COG0510, ycfN, Thiamine kinase and related kinases [Coenzyme transport and metabolism].	5.2385e-83
NZ_AP017377.1\|WP_000004335.1\|972801_974463_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.63186e-123
NZ_AP017377.1\|WP_000163826.1\|982155_982467_-\|PepSY-domain-containing-protein	gnl\|CDD\|227871	COG5584, COG5584, Predicted small secreted protein [Function unknown].	4.78628e-46
NZ_AP017377.1\|WP_001549041.1\|961373_963791_+\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_AP017377.1\|WP_000526539.1\|958841_959795_-\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	0
NZ_AP017377.1\|WP_001024576.1\|982553_983630_+\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	2.36515e-152
NZ_AP017377.1\|WP_024937151.1\|980074_980719_+\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	4.12513e-86
NZ_AP017377.1\|WP_000265417.1\|976457_977867_+\|Mn(2+)-dependent-dipeptidase-Sapep	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
NZ_AP017377.1\|WP_000411085.1\|977870_978719_+\|D-amino-acid-transaminase	gnl\|CDD\|130191	TIGR01121, D-alanine_aminotransferase, D-amino acid aminotransferase. This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. [Energy metabolism, Amino acids and amines].	6.28892e-159
NZ_AP017377.1\|WP_000811163.1\|983694_984006_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.34221e-24
NZ_AP017377.1\|WP_000689580.1\|981188_982031_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293814	cd07728, YtnP-like_MBL-fold, Bacillus subtilis YtnP and related proteins; MBL-fold metallo hydrolase domain. Bacillus subtilis YtnP inhibits the signaling pathway required for the streptomycin production and development of aerial mycelium in Streptomyces griseus. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.38932e-155
NZ_AP017377.1\|WP_001050548.1\|964449_971010_+\|LPXTG-anchored-repetitive-surface-protein-SasC	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	2.99104e-115
NZ_AP017377.1\|WP_001048369.1\|984991_985588_+\|DUF4479-domain-containing-protein	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	9.82919e-48
NZ_AP017377.1\|WP_000836465.1\|963812_964124_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.46882e-25
NZ_AP017377.1\|WP_001025061.1\|959904_961086_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.66072e-94
NZ_AP017377.1\|WP_001091387.1\|984105_984963_+\|DUF1444-domain-containing-protein	gnl\|CDD\|237463	PRK13668, PRK13668, hypothetical protein; Provisional.	2.02352e-168
NZ_AP017377.1\|WP_001051860.1\|975171_975594_+\|YtxH-domain-containing-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	0.000542053
NZ_AP017377.1\|WP_000764419.1\|958281_958845_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	2.38341e-67
NZ_AP017377.1\|WP_000285019.1\|971126_972395_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0

>NZ_AP017377.1|WP_001051860.1|975171_975594_+|YtxH-domain-containing-protein
MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQSYKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFKEEKSKFTEYDNKTDESIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE
>NZ_AP017377.1|WP_001217125.1|974459_975155_+|rRNA-pseudouridine-synthase
MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPENDKITVRGELIEYIENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLDKDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVTLTDGKVKPAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYRLLTENDFDKLNYK
>NZ_AP017377.1|WP_000004335.1|972801_974463_+|polysaccharide-biosynthesis-protein
MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNIHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKSMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR
>NZ_AP017377.1|WP_000285019.1|971126_972395_-|NAD(P)/FAD-dependent-oxidoreductase
MYQTIIIGGGPSGLMAAVAASEQSSSVLLIEKKKGLGRKLKISGGGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMFPVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQNNSYESHSLVIATGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVELSVLKKNGKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPELNHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLNDLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHGYTGGYNITSALVTGHVAGLYAGHYSHASME
>NZ_AP017377.1|WP_001050548.1|964449_971010_+|LPXTG-anchored-repetitive-surface-protein-SasC
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDKDVANNRGLANSAQNTPNQSATTNQATNQALVNHNNGSIVNQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNNDVVSNNTALNVPTKTNENGSGGHLTLKEIQEDVRHSSNKPELVAIAEPASNRPKKRSRRAAPADPNATPADPAAAAVGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPTVNVVNNLPGFTLINGGKVGVFSHAMVRTSMFDSGDNKNYQAQGNVIALGRIHGTDTNDHGDFNGIEKALTVNPNSELIFEFNTMTTKNGQGATNVIIKNADTNDTIAEKTVEGGPTLRLFKVPDNVRNLKIQFVPKNDAITDARGIYQLKDGYKYYSFVDSIGLHSGSHVFVERRTMDPTATNNKEFTVTTSLKNNGNSGASLDTNDFVYQVQLPEGVEYVNNSLTKDFPSNNSGVDVNDMNVTYDAANRVITIKSTGGGTANSPARLMPDKILDLRYKLRVNNVPTPRTVTFNETLTYKTYTQDFINSAAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNGLKRRAQTILDENRNNVPLNKRVSQAYIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDVTEDEIQDALNQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKKAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDTRNVVNDKAREAITNINATTGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQINQNQTNDQVDTTTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVTPDHIVRAAARDAVKQQYEAKKREIEQAEHATDEEKQVALNQLANNEKRALQNIDQAIANNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>NZ_AP017377.1|WP_000836465.1|963812_964124_+|rhodanese-like-domain-containing-protein
MKSITTDELKNKLLESKPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>NZ_AP017377.1|WP_001549041.1|961373_963791_+|leucine--tRNA-ligase
MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYATNPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLAIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>NZ_AP017377.1|WP_001025061.1|959904_961086_+|MFS-transporter
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>NZ_AP017377.1|WP_000526539.1|958841_959795_-|TIGR01212-family-radical-SAM-protein
MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>NZ_AP017377.1|WP_000764419.1|958281_958845_-|class-I-SAM-dependent-methyltransferase
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYLPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQKHAQVLQYQFLNQRNHAPFICAIEKIS
>NZ_AP017377.1|WP_000265417.1|976457_977867_+|Mn(2+)-dependent-dipeptidase-Sapep
MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
>NZ_AP017377.1|WP_000411085.1|977870_978719_+|D-amino-acid-transaminase
MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
>NZ_AP017377.1|WP_000434765.1|979268_980060_+|phosphotransferase-family-protein
MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSMLKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDVNHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI
>NZ_AP017377.1|WP_024937151.1|980074_980719_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MRVRYKPWAEDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNSHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
>NZ_AP017377.1|WP_000689580.1|981188_982031_+|MBL-fold-metallo-hydrolase
MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDYSNKLILFEKHFEPVLGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLWVTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDNGENIDAYILRETLVDNN
>NZ_AP017377.1|WP_000163826.1|982155_982467_-|PepSY-domain-containing-protein
MTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKSYFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVER
>NZ_AP017377.1|WP_001024576.1|982553_983630_+|M42-family-metallopeptidase
MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFIENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQGQRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGDTIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGLRGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPVFRDYLLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYFAARSLLSEAICNLDNNQIETLQYK
>NZ_AP017377.1|WP_000811163.1|983694_984006_+|thioredoxin-family-protein
MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARYPMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQYV
>NZ_AP017377.1|WP_001091387.1|984105_984963_+|DUF1444-domain-containing-protein
MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
>NZ_AP017377.1|WP_001048369.1|984991_985588_+|DUF4479-domain-containing-protein
MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVGYNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNANLSPKFVVGYVETKDKHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGVASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE

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Crispr_ID: NZ_AP017377_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_6

1684299-1684485

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCC	CRT

3 spacers

The CRISPR arrays of NZ_AP017377_6

>merge|NZ_AP017377|6|1684299-1684485|CRT
TCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCACTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCACCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCC

>NZ_AP017377|6|2|1684299-1684485|CRT
TCTATGTTGGGGCCCCGCC	AACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTC
ACTATGTTGGGGCCCCGCC	AACTTGCACATTATTGTAAGCTGACTTTTCGTCAGCT
TCTGTGTTGGGGCCCACCC	CAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTC
TCTATGTTGGGGCCCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_001802045.1\|1684640_1684865_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000793605.1\|1680275_1681277_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_AP017377.1\|WP_000791587.1\|1689273_1689771_-\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_AP017377.1\|WP_000041896.1\|1683367_1684084_+\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NZ_AP017377.1\|WP_000739563.1\|1692539_1692941_+\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_AP017377.1\|WP_000231632.1\|1687076_1687310_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000195429.1\|1689955_1691128_+\|IS256-like-element-IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_AP017377.1\|WP_000584398.1\|1691361_1691868_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000432077.1\|1677592_1679149_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_AP017377.1\|WP_000739523.1\|1681714_1682440_+\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_AP017377.1\|WP_001245802.1\|1675368_1675557_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_AP017377.1\|WP_000149423.1\|1677057_1677285_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000669537.1\|1688769_1689120_-\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NZ_AP017377.1\|WP_042855192.1\|1679320_1680253_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_AP017377.1\|WP_000765708.1\|1684821_1684968_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000398672.1\|1674322_1674457_-\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_AP017377.1\|WP_001032814.1\|1687931_1688117_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_001239288.1\|1675805_1676753_+\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_AP017377.1\|WP_000857483.1\|1685640_1686600_+\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
NZ_AP017377.1\|WP_001063559.1\|1682534_1683260_+\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_000791587.1\|1689273_1689771_-\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.40265e-27
NZ_AP017377.1\|WP_000041896.1\|1683367_1684084_+\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
NZ_AP017377.1\|WP_000739563.1\|1692539_1692941_+\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	3.87075e-77
NZ_AP017377.1\|WP_000195429.1\|1689955_1691128_+\|IS256-like-element-IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	0
NZ_AP017377.1\|WP_000432077.1\|1677592_1679149_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_AP017377.1\|WP_000739523.1\|1681714_1682440_+\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
NZ_AP017377.1\|WP_000793605.1\|1680275_1681277_-\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_AP017377.1\|WP_001245802.1\|1675368_1675557_-\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NZ_AP017377.1\|WP_001063559.1\|1682534_1683260_+\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NZ_AP017377.1\|WP_042855192.1\|1679320_1680253_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_AP017377.1\|WP_000857483.1\|1685640_1686600_+\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	4.27434e-141
NZ_AP017377.1\|WP_001239288.1\|1675805_1676753_+\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	1.39126e-83
NZ_AP017377.1\|WP_000669537.1\|1688769_1689120_-\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NZ_AP017377.1\|WP_000398672.1\|1674322_1674457_-\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13

>NZ_AP017377.1|WP_000041896.1|1683367_1684084_+|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NZ_AP017377.1|WP_001063559.1|1682534_1683260_+|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_AP017377.1|WP_000739523.1|1681714_1682440_+|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_AP017377.1|WP_000793605.1|1680275_1681277_-|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_AP017377.1|WP_042855192.1|1679320_1680253_-|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFTKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_AP017377.1|WP_000432077.1|1677592_1679149_-|YfcC-family-protein
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NZ_AP017377.1|WP_000149423.1|1677057_1677285_-|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_AP017377.1|WP_001239288.1|1675805_1676753_+|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLKNVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NZ_AP017377.1|WP_001245802.1|1675368_1675557_-|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NZ_AP017377.1|WP_000398672.1|1674322_1674457_-|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
>NZ_AP017377.1|WP_001802045.1|1684640_1684865_-|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_AP017377.1|WP_000765708.1|1684821_1684968_-|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_AP017377.1|WP_000857483.1|1685640_1686600_+|alpha-hemolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>NZ_AP017377.1|WP_000231632.1|1687076_1687310_+|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_AP017377.1|WP_001032814.1|1687931_1688117_+|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_AP017377.1|WP_000669537.1|1688769_1689120_-|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NZ_AP017377.1|WP_000791587.1|1689273_1689771_-|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>NZ_AP017377.1|WP_000195429.1|1689955_1691128_+|IS256-like-element-IS256-family-transposase
MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEYIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK
>NZ_AP017377.1|WP_000584398.1|1691361_1691868_-|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_AP017377.1|WP_000739563.1|1692539_1692941_+|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY

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Crispr_ID: NZ_AP017377_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_7

1951914-1951999

Orphan

Consensus_repeat	Method
CCAACTTGCACACTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP017377_7

>merge|NZ_AP017377|7|1951914-1951999|CRISPRCasFinder
CCAACTTGCACACTATTGTAAGCTGACTTTTCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACACTATTGTAAGCTGACTTT

>NZ_AP017377|7|5|1951914-1951999|CRISPRCasFinder
CCAACTTGCACACTATTGTAAGCTGACTTT	TCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACACTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_000138487.1\|1952149_1953394_-\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_AP017377.1\|WP_000167314.1\|1953502_1954693_-\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
NZ_AP017377.1\|WP_001038688.1\|1961852_1962572_-\|serine-protease-SplF	unknown	unknown	gnl\|CDD\|226119
NZ_AP017377.1\|WP_000072576.1\|1958741_1959941_-\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341151
NZ_AP017377.1\|WP_000195429.1\|1957235_1958408_+\|IS256-like-element-IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_AP017377.1\|WP_000838037.1\|1955000_1956128_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_AP017377.1\|WP_000711486.1\|1944313_1944889_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_AP017377.1\|WP_000172342.1\|1940677_1944154_-\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_AP017377.1\|WP_009559872.1\|1959933_1961490_-\|type-I-restriction-modification-system-subunit-M	unknown	unknown	gnl\|CDD\|223363
NZ_AP017377.1\|WP_001038759.1\|1962722_1963439_-\|serine-protease-SplE	unknown	unknown	gnl\|CDD\|226119
NZ_AP017377.1\|WP_001067294.1\|1956489_1956867_-\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224023
NZ_AP017377.1\|WP_000185319.1\|1950831_1951761_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_AP017377.1\|WP_000148855.1\|1946333_1947665_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_AP017377.1\|WP_000154914.1\|1937023_1940677_-\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_AP017377.1\|WP_000066053.1\|1949210_1950590_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_AP017377.1\|WP_000660045.1\|1948015_1949221_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_AP017377.1\|WP_000007967.1\|1945433_1946009_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_AP017377.1\|WP_000758215.1\|1944904_1945429_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_AP017377.1\|WP_000670752.1\|1935955_1936858_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_AP017377.1\|WP_001791797.1\|1961653_1961788_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_000138487.1\|1952149_1953394_-\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NZ_AP017377.1\|WP_000167314.1\|1953502_1954693_-\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_AP017377.1\|WP_001038688.1\|1961852_1962572_-\|serine-protease-SplF	gnl\|CDD\|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	9.42253e-79
NZ_AP017377.1\|WP_000072576.1\|1958741_1959941_-\|restriction-endonuclease-subunit-S	gnl\|CDD\|341151	cd17262, RMtype1_S_Aco12261I-TRD2-CR2, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Aminobacterium colombiense DSM 12261 S subunit (S.Aco12261I) TRD2-CR2 and Moraxella catarrhalis S subunit (S.Mca353ORF290P) TRD2-CR2. Aminobacterium colombiense DSM 12261 S subunit (S.Aco12261I) recognizes 5'... GCANNNNNNTGT ... 3', and Moraxella catarrhalis S subunit (S.Mca353ORF290P) recognizes 5'... CAAGNNNNNNTGT ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	3.02384e-64
NZ_AP017377.1\|WP_000195429.1\|1957235_1958408_+\|IS256-like-element-IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	0
NZ_AP017377.1\|WP_000838037.1\|1955000_1956128_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_AP017377.1\|WP_000711486.1\|1944313_1944889_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.05406e-53
NZ_AP017377.1\|WP_000172342.1\|1940677_1944154_-\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_AP017377.1\|WP_009559872.1\|1959933_1961490_-\|type-I-restriction-modification-system-subunit-M	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	2.18528e-151
NZ_AP017377.1\|WP_001038759.1\|1962722_1963439_-\|serine-protease-SplE	gnl\|CDD\|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	3.12022e-61
NZ_AP017377.1\|WP_001067294.1\|1956489_1956867_-\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
NZ_AP017377.1\|WP_000185319.1\|1950831_1951761_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
NZ_AP017377.1\|WP_000148855.1\|1946333_1947665_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_AP017377.1\|WP_000154914.1\|1937023_1940677_-\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_AP017377.1\|WP_000066053.1\|1949210_1950590_+\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_AP017377.1\|WP_000660045.1\|1948015_1949221_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_AP017377.1\|WP_000007967.1\|1945433_1946009_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
NZ_AP017377.1\|WP_000758215.1\|1944904_1945429_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.63848e-48
NZ_AP017377.1\|WP_000670752.1\|1935955_1936858_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87

>NZ_AP017377.1|WP_000185319.1|1950831_1951761_+|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>NZ_AP017377.1|WP_000066053.1|1949210_1950590_+|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>NZ_AP017377.1|WP_000660045.1|1948015_1949221_+|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>NZ_AP017377.1|WP_000148855.1|1946333_1947665_-|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>NZ_AP017377.1|WP_000007967.1|1945433_1946009_-|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>NZ_AP017377.1|WP_000758215.1|1944904_1945429_-|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDQDNNKHDSRQFGLIDKKDIIGNVSLRYYPFSKWTVQFKS
>NZ_AP017377.1|WP_000711486.1|1944313_1944889_-|signal-peptidase-I
MKKEILEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIVGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>NZ_AP017377.1|WP_000172342.1|1940677_1944154_-|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_AP017377.1|WP_000154914.1|1937023_1940677_-|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPKNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDSVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_AP017377.1|WP_000670752.1|1935955_1936858_-|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>NZ_AP017377.1|WP_000138487.1|1952149_1953394_-|Glu/Leu/Phe/Val-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>NZ_AP017377.1|WP_000167314.1|1953502_1954693_-|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>NZ_AP017377.1|WP_000838037.1|1955000_1956128_-|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSNIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>NZ_AP017377.1|WP_001067294.1|1956489_1956867_-|S1-RNA-binding-domain-containing-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>NZ_AP017377.1|WP_000195429.1|1957235_1958408_+|IS256-like-element-IS256-family-transposase
MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEYIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK
>NZ_AP017377.1|WP_000072576.1|1958741_1959941_-|restriction-endonuclease-subunit-S
MSNTQKKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSENYTNKGIPFLRSQNIRNGKLNLNDLVYISKDIDDEMKNSRTYYGDVLLNITGASIGRTAINSIVETHANLNQHVCIIRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFKEIANLKIFTPTIFEEQQKIGKFFSKLDRQIELEEQKLELLQQQKKGYMQKIFTQELRFKDENGEEYPEWENKFIKDIFIFENNRRKPITSSLREKGLYPYYGATGIIDYVKDYLFNNEERLLIGEDGAKWGQFETSSFIANGQYWVNNHAHVVKSNDHNLFFMNYYLNFKELRAFVTGNAPAKLTHANLCNINLKIPCLTEQDKVSALLKSIDNKMNNQMNRIELLKERKKGLLQKMFI
>NZ_AP017377.1|WP_009559872.1|1959933_1961490_-|type-I-restriction-modification-system-subunit-M
MSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADALSGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIRKVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEIDMLGDAYEFLIGHFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLLRVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFDIRNDDTLENPAFLGNTFDAVIANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDDEGTMAVVLPHGVLFRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASNDFEKGKNQNHLSDAQVERIIDTYKRKETIDKYSYSATLQEIADNDYNLNIPRYVDTFEEEAPIDLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE
>NZ_AP017377.1|WP_001791797.1|1961653_1961788_-|hypothetical-protein
MHYLICIKANQRLIFTNSIVDWFYLCMNEQLFDIIKNINDFESI
>NZ_AP017377.1|WP_001038688.1|1961852_1962572_-|serine-protease-SplF
MNKNIIIKSIAALTILTSITGVGTTMVEGIQQTAKAENTVKQITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVSSDAIIQPGSSGSPILNSKHEAIGVIYAGNKPSGESTRGFAVYFSPEIKKFIADNLDK
>NZ_AP017377.1|WP_001038759.1|1962722_1963439_-|serine-protease-SplE
MNKNIIIKSIAALTILTSVTGVGTTVVEGIQQTAKAEHNVKLIKNTNVAPYNGVVSIGSGTGFIVGKNTIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYKVKKIVRYSGQEDIAILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYINKFQMYESTGKVLSVKGNMIITDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKSTKGYGVYFSPEIKKFIADNTDK

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Crispr_ID: NZ_AP017377_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_8

2288850-2289000

Orphan

Consensus_repeat	Method
AACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NZ_AP017377_8

>merge|NZ_AP017377|8|2288850-2289000|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCTTTCTA

>NZ_AP017377|8|6|2288850-2289000|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTTA
AACTTTAGTTGTTAGGGGCTCTTATGCA	GTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTC
AACTTTAGTTGTTAGGGGCTTCTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_000495671.1\|2287740_2288832_+\|lytic-regulatory-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000160304.1\|2279331_2280042_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_AP017377.1\|WP_000908176.1\|2293269_2294052_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_AP017377.1\|WP_000123393.1\|2281676_2283050_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_AP017377.1\|WP_024937201.1\|2294283_2296089_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_AP017377.1\|WP_001802298.1\|2289331_2289436_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000019744.1\|2286494_2287475_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_AP017377.1\|WP_096377499.1\|2292344_2293202_-\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223635
NZ_AP017377.1\|WP_000083807.1\|2296769_2298308_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_AP017377.1\|WP_001024094.1\|2285355_2286021_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_AP017377.1\|WP_001127960.1\|2283982_2284921_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_AP017377.1\|WP_000808817.1\|2283721_2283952_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_001790138.1\|2291547_2291640_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000927363.1\|2298342_2300475_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_AP017377.1\|WP_001292149.1\|2300486_2300921_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_AP017377.1\|WP_000070866.1\|2280162_2280606_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_AP017377.1\|WP_000003759.1\|2286172_2286493_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_AP017377.1\|WP_000115564.1\|2290122_2291259_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_AP017377.1\|WP_000648718.1\|2300920_2302027_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_AP017377.1\|WP_001123303.1\|2280805_2281219_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_024937201.1\|2294283_2296089_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_AP017377.1\|WP_000160304.1\|2279331_2280042_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_AP017377.1\|WP_000908176.1\|2293269_2294052_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	4.88024e-103
NZ_AP017377.1\|WP_000123393.1\|2281676_2283050_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_AP017377.1\|WP_000019744.1\|2286494_2287475_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
NZ_AP017377.1\|WP_000083807.1\|2296769_2298308_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_AP017377.1\|WP_001024094.1\|2285355_2286021_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.74381e-48
NZ_AP017377.1\|WP_001127960.1\|2283982_2284921_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_AP017377.1\|WP_000927363.1\|2298342_2300475_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
NZ_AP017377.1\|WP_001292149.1\|2300486_2300921_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_AP017377.1\|WP_096377499.1\|2292344_2293202_-\|HAD-family-phosphatase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	2.67555e-58
NZ_AP017377.1\|WP_000648718.1\|2300920_2302027_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_AP017377.1\|WP_000003759.1\|2286172_2286493_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_AP017377.1\|WP_000115564.1\|2290122_2291259_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.91533e-06
NZ_AP017377.1\|WP_000070866.1\|2280162_2280606_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_AP017377.1\|WP_001123303.1\|2280805_2281219_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46

>NZ_AP017377.1|WP_000495671.1|2287740_2288832_+|lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_AP017377.1|WP_000019744.1|2286494_2287475_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_AP017377.1|WP_000003759.1|2286172_2286493_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_AP017377.1|WP_001024094.1|2285355_2286021_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>NZ_AP017377.1|WP_001127960.1|2283982_2284921_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_AP017377.1|WP_000808817.1|2283721_2283952_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_AP017377.1|WP_000123393.1|2281676_2283050_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_AP017377.1|WP_001123303.1|2280805_2281219_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_AP017377.1|WP_000070866.1|2280162_2280606_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_AP017377.1|WP_000160304.1|2279331_2280042_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_AP017377.1|WP_001802298.1|2289331_2289436_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_AP017377.1|WP_000115564.1|2290122_2291259_-|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>NZ_AP017377.1|WP_001790138.1|2291547_2291640_+|hypothetical-protein
MFIFKTTSKSHFHNNVKSLECIKIPINKNR
>NZ_AP017377.1|WP_096377499.1|2292344_2293202_-|HAD-family-phosphatase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQVLTSDVTAYTNEEDGAAKYLAEHFLAE
>NZ_AP017377.1|WP_000908176.1|2293269_2294052_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMFAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_AP017377.1|WP_024937201.1|2294283_2296089_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDATDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_AP017377.1|WP_000083807.1|2296769_2298308_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_AP017377.1|WP_000927363.1|2298342_2300475_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_AP017377.1|WP_001292149.1|2300486_2300921_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_AP017377.1|WP_000648718.1|2300920_2302027_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

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Crispr_ID: NZ_AP017377_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017377_9

2413012-2413205

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of NZ_AP017377_9

>merge|NZ_AP017377|9|2413012-2413205|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>NZ_AP017377|9|3|2413012-2413205|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017377.1\|WP_000066900.1\|2412305_2412656_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_AP017377.1\|WP_000230173.1\|2413346_2414369_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_AP017377.1\|WP_000503817.1\|2417993_2418500_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_AP017377.1\|WP_000643988.1\|2414388_2414988_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_AP017377.1\|WP_000808500.1\|2415233_2415680_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_AP017377.1\|WP_000076929.1\|2418530_2419535_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NZ_AP017377.1\|WP_000866971.1\|2414994_2415228_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_AP017377.1\|WP_000134528.1\|2417497_2417992_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_AP017377.1\|WP_001161085.1\|2403948_2404266_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000184419.1\|2410992_2412204_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_AP017377.1\|WP_000413865.1\|2407736_2409002_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_AP017377.1\|WP_000592303.1\|2404452_2407620_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_AP017377.1\|WP_000600967.1\|2409633_2410398_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_AP017377.1\|WP_001790034.1\|2412781_2412952_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000951058.1\|2410559_2411000_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_AP017377.1\|WP_001549681.1\|2409390_2409642_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000913019.1\|2419704_2420310_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_AP017377.1\|WP_000259718.1\|2416175_2417435_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_AP017377.1\|WP_000051206.1\|2403539_2403704_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017377.1\|WP_000602937.1\|2415693_2416179_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677

Protein	Function_ID	Function_description	E-value
NZ_AP017377.1\|WP_000066900.1\|2412305_2412656_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_AP017377.1\|WP_000230173.1\|2413346_2414369_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_AP017377.1\|WP_000643988.1\|2414388_2414988_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_AP017377.1\|WP_000076929.1\|2418530_2419535_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
NZ_AP017377.1\|WP_000808500.1\|2415233_2415680_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_AP017377.1\|WP_000134528.1\|2417497_2417992_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98
NZ_AP017377.1\|WP_000184419.1\|2410992_2412204_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
NZ_AP017377.1\|WP_000602937.1\|2415693_2416179_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NZ_AP017377.1\|WP_000592303.1\|2404452_2407620_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_AP017377.1\|WP_000600967.1\|2409633_2410398_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_AP017377.1\|WP_000413865.1\|2407736_2409002_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
NZ_AP017377.1\|WP_000951058.1\|2410559_2411000_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_AP017377.1\|WP_000866971.1\|2414994_2415228_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_AP017377.1\|WP_000913019.1\|2419704_2420310_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NZ_AP017377.1\|WP_000259718.1\|2416175_2417435_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
NZ_AP017377.1\|WP_000503817.1\|2417993_2418500_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.02752e-64

>NZ_AP017377.1|WP_001790034.1|2412781_2412952_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_AP017377.1|WP_000066900.1|2412305_2412656_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_AP017377.1|WP_000184419.1|2410992_2412204_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_AP017377.1|WP_000951058.1|2410559_2411000_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_AP017377.1|WP_000600967.1|2409633_2410398_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_AP017377.1|WP_001549681.1|2409390_2409642_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_AP017377.1|WP_000413865.1|2407736_2409002_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_AP017377.1|WP_000592303.1|2404452_2407620_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_AP017377.1|WP_001161085.1|2403948_2404266_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_AP017377.1|WP_000051206.1|2403539_2403704_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_AP017377.1|WP_000230173.1|2413346_2414369_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_AP017377.1|WP_000643988.1|2414388_2414988_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_AP017377.1|WP_000866971.1|2414994_2415228_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_AP017377.1|WP_000808500.1|2415233_2415680_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_AP017377.1|WP_000602937.1|2415693_2416179_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_AP017377.1|WP_000259718.1|2416175_2417435_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_AP017377.1|WP_000134528.1|2417497_2417992_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_AP017377.1|WP_000503817.1|2417993_2418500_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIDGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_AP017377.1|WP_000076929.1|2418530_2419535_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_AP017377.1|WP_000913019.1|2419704_2420310_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP017377_4	4.1\|869222\|34\|NZ_AP017377\|CRISPRCasFinder	869222-869255	34	NZ_AP017377.1	1382245-1382278	0	1.0
NZ_AP017377_4	4.1\|869222\|34\|NZ_AP017377\|CRISPRCasFinder	869222-869255	34	NZ_AP017377.1	1472764-1472797	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	151410-151427	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	294606-294623	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	376481-376498	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	820401-820418	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	820456-820473	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	820511-820528	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	820566-820583	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	826059-826076	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	826117-826134	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	869278-869295	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	976167-976184	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1154709-1154726	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1382146-1382163	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1472879-1472896	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1804520-1804537	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1932413-1932430	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	2055378-2055395	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	2604616-2604633	0	1.0
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	2854674-2854691	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	151467-151503	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	660999-661035	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	778327-778363	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	779297-779333	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	825982-826018	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	1382262-1382298	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	1472744-1472780	0	1.0
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	2055418-2055454	0	1.0
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	376367-376403	0	1.0
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	1472802-1472838	0	1.0
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	1830711-1830747	0	1.0
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	2053961-2053997	0	1.0
NZ_AP017377_5	5.1\|975935\|22\|NZ_AP017377\|CRT	975935-975956	22	NZ_AP017377.1	976108-976129	1	0.955
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	294661-294678	1	0.944
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	833326-833343	1	0.944
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1120743-1120760	1	0.944
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1423551-1423568	1	0.944
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1468457-1468474	1	0.944
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	2064727-2064744	1	0.944
NZ_AP017377_5	5.3\|976049\|22\|NZ_AP017377\|CRT	976049-976070	22	NZ_AP017377.1	976108-976129	1	0.955
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	1804578-1804614	1	0.973
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	2579333-2579369	1	0.973
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	1154651-1154687	1	0.973
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	1382204-1382240	1	0.973
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	2687933-2687969	1	0.973
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	976148-976184	1	0.973
NZ_AP017377_7	7.1\|1951944\|26\|NZ_AP017377\|CRISPRCasFinder	1951944-1951969	26	NZ_AP017377.1	2053989-2054014	1	0.962
NZ_AP017377_9	9.2\|2413091\|36\|NZ_AP017377\|CRT	2413091-2413126	36	NZ_AP017377.1	976153-976188	1	0.972
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	328615-328632	2	0.889
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	793381-793398	2	0.889
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	936761-936778	2	0.889
NZ_AP017377_5	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	NZ_AP017377.1	1045812-1045829	2	0.889
NZ_AP017377_6	6.1\|1684318\|37\|NZ_AP017377\|CRT	1684318-1684354	37	NZ_AP017377.1	1688286-1688322	2	0.946
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	825926-825962	2	0.946
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	1684262-1684298	2	0.946
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	1688342-1688378	2	0.946
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	2053902-2053938	2	0.946
NZ_AP017377_6	6.2\|1684374\|37\|NZ_AP017377\|CRT	1684374-1684410	37	NZ_AP017377.1	2854600-2854636	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	820382-820418	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	820437-820473	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	820492-820528	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	820547-820583	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	869259-869295	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	1154709-1154745	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	2064708-2064744	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	2604616-2604652	2	0.946
NZ_AP017377_6	6.3\|1684430\|37\|NZ_AP017377\|CRT	1684430-1684466	37	NZ_AP017377.1	2854655-2854691	2	0.946
NZ_AP017377_7	7.1\|1951944\|26\|NZ_AP017377\|CRISPRCasFinder	1951944-1951969	26	NZ_AP017377.1	376350-376375	2	0.923
NZ_AP017377_9	9.1\|2413035\|33\|NZ_AP017377\|CRT	2413035-2413067	33	NZ_AP017377.1	1382200-1382232	2	0.939
NZ_AP017377_9	9.1\|2413035\|33\|NZ_AP017377\|CRT	2413035-2413067	33	NZ_AP017377.1	1472810-1472842	2	0.939
NZ_AP017377_9	9.1\|2413035\|33\|NZ_AP017377\|CRT	2413035-2413067	33	NZ_AP017377.1	2053969-2054001	2	0.939
NZ_AP017377_9	9.1\|2413035\|33\|NZ_AP017377\|CRT	2413035-2413067	33	NZ_AP017377.1	2687941-2687973	2	0.939
NZ_AP017377_9	9.2\|2413091\|36\|NZ_AP017377\|CRT	2413091-2413126	36	NZ_AP017377.1	1154705-1154740	2	0.944
NZ_AP017377_9	9.2\|2413091\|36\|NZ_AP017377\|CRT	2413091-2413126	36	NZ_AP017377.1	2064713-2064748	2	0.944
NZ_AP017377_9	9.3\|2413150\|33\|NZ_AP017377\|CRT	2413150-2413182	33	NZ_AP017377.1	825934-825966	2	0.939
NZ_AP017377_9	9.3\|2413150\|33\|NZ_AP017377\|CRT	2413150-2413182	33	NZ_AP017377.1	1472810-1472842	2	0.939
NZ_AP017377_9	9.3\|2413150\|33\|NZ_AP017377\|CRT	2413150-2413182	33	NZ_AP017377.1	2053969-2054001	2	0.939
NZ_AP017377_9	9.3\|2413150\|33\|NZ_AP017377\|CRT	2413150-2413182	33	NZ_AP017377.1	2687941-2687973	2	0.939

1. spacer 4.1|869222|34|NZ_AP017377|CRISPRCasFinder matches to position: 1382245-1382278, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

2. spacer 4.1|869222|34|NZ_AP017377|CRISPRCasFinder matches to position: 1472764-1472797, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 151410-151427, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

4. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 294606-294623, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

5. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 376481-376498, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

6. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 820401-820418, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

7. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 820456-820473, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

8. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 820511-820528, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

9. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 820566-820583, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

10. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 826059-826076, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

11. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 826117-826134, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

12. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 869278-869295, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

13. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 976167-976184, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

14. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1154709-1154726, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

15. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1382146-1382163, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

16. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1472879-1472896, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

17. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1804520-1804537, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

18. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1932413-1932430, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

19. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 2055378-2055395, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

20. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 2604616-2604633, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

21. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 2854674-2854691, mismatch: 0, identity: 1.0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

22. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 151467-151503, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

23. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 660999-661035, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

24. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 778327-778363, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

25. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 779297-779333, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

26. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 825982-826018, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

27. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 1382262-1382298, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

28. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 1472744-1472780, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

29. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 2055418-2055454, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

30. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 376367-376403, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

31. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 1472802-1472838, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

32. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 1830711-1830747, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

33. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 2053961-2053997, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

34. spacer 5.1|975935|22|NZ_AP017377|CRT matches to position: 976108-976129, mismatch: 1, identity: 0.955

gaaagctgactattggccagct	CRISPR spacer
gaaagctaactattggccagct	Protospacer
*******.**************

35. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 294661-294678, mismatch: 1, identity: 0.944

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaatttc	Protospacer
************** ***

36. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 833326-833343, mismatch: 1, identity: 0.944

aatttcttttcgaaattc	CRISPR spacer
aatttcatttcgaaattc	Protospacer
****** ***********

37. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1120743-1120760, mismatch: 1, identity: 0.944

aatttcttttcgaaattc	CRISPR spacer
aatttctttacgaaattc	Protospacer
********* ********

38. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1423551-1423568, mismatch: 1, identity: 0.944

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaaatc	Protospacer
*************** **

39. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1468457-1468474, mismatch: 1, identity: 0.944

aatttcttttcgaaattc	CRISPR spacer
aatttcttatcgaaattc	Protospacer
******** *********

40. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 2064727-2064744, mismatch: 1, identity: 0.944

aatttcttttcgaaattc	CRISPR spacer
aatttcctttcgaaattc	Protospacer
******.***********

41. spacer 5.3|976049|22|NZ_AP017377|CRT matches to position: 976108-976129, mismatch: 1, identity: 0.955

gaaagctgactattggccagct	CRISPR spacer
gaaagctaactattggccagct	Protospacer
*******.**************

42. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 1804578-1804614, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttacattgtctgtagaaattgggaatccaatttc	Protospacer
*****.*******************************

43. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 2579333-2579369, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctctagaaattgggaatccaatttc	Protospacer
************** **********************

44. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 1154651-1154687, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattatagtaagctgacttttcgtcagct	Protospacer
************** **********************

45. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 1382204-1382240, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcatct	Protospacer
********************************** **

46. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 2687933-2687969, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aactcgcacattattgtaagctgacttttcgtcagct	Protospacer
****.********************************

47. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 976148-976184, mismatch: 1, identity: 0.973

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtctgtagaatttcttttcgaaattc	Protospacer
*****************************.*******

48. spacer 7.1|1951944|26|NZ_AP017377|CRISPRCasFinder matches to position: 2053989-2054014, mismatch: 1, identity: 0.962

tcgccagcttctgtgttggggccccg	CRISPR spacer
tcgtcagcttctgtgttggggccccg	Protospacer
***.**********************

49. spacer 9.2|2413091|36|NZ_AP017377|CRT matches to position: 976153-976188, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

50. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 328615-328632, mismatch: 2, identity: 0.889

aatttcttttcgaaattc	CRISPR spacer
aatttttcttcgaaattc	Protospacer
*****.*.**********

51. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 793381-793398, mismatch: 2, identity: 0.889

aatttcttttcgaaattc	CRISPR spacer
aattcctttttgaaattc	Protospacer
****.*****.*******

52. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 936761-936778, mismatch: 2, identity: 0.889

aatttcttttcgaaattc	CRISPR spacer
aatttctttttgaacttc	Protospacer
**********.*** ***

53. spacer 5.2|975994|18|NZ_AP017377|CRT matches to position: 1045812-1045829, mismatch: 2, identity: 0.889

aatttcttttcgaaattc	CRISPR spacer
aatttctttttgaacttc	Protospacer
**********.*** ***

54. spacer 6.1|1684318|37|NZ_AP017377|CRT matches to position: 1688286-1688322, mismatch: 2, identity: 0.946

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattggggttccaatttc	Protospacer
**************************. *********

55. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 825926-825962, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

56. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 1684262-1684298, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

57. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 1688342-1688378, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacatttttgtaagctgacttttcgccagct	Protospacer
************ ******************.*****

58. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 2053902-2053938, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacctgcacattatcgtaagctgacttttcgtcagct	Protospacer
***.**********.**********************

59. spacer 6.2|1684374|37|NZ_AP017377|CRT matches to position: 2854600-2854636, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

60. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 820382-820418, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
*************.***************.*******

61. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 820437-820473, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
*************.***************.*******

62. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 820492-820528, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
*************.***************.*******

63. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 820547-820583, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
*************.***************.*******

64. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 869259-869295, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

65. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 1154709-1154745, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

66. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 2064708-2064744, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtctgtagaatttcctttcgaaattc	Protospacer
*************************.***.*******

67. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 2604616-2604652, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

68. spacer 6.3|1684430|37|NZ_AP017377|CRT matches to position: 2854655-2854691, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
*************.***************.*******

69. spacer 7.1|1951944|26|NZ_AP017377|CRISPRCasFinder matches to position: 376350-376375, mismatch: 2, identity: 0.923

tcgccagcttctgtgttggggccccg	CRISPR spacer
tcgtcagcttctttgttggggccccg	Protospacer
***.******** *************

70. spacer 9.1|2413035|33|NZ_AP017377|CRT matches to position: 1382200-1382232, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

71. spacer 9.1|2413035|33|NZ_AP017377|CRT matches to position: 1472810-1472842, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

72. spacer 9.1|2413035|33|NZ_AP017377|CRT matches to position: 2053969-2054001, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

73. spacer 9.1|2413035|33|NZ_AP017377|CRT matches to position: 2687941-2687973, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

74. spacer 9.2|2413091|36|NZ_AP017377|CRT matches to position: 1154705-1154740, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

75. spacer 9.2|2413091|36|NZ_AP017377|CRT matches to position: 2064713-2064748, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

76. spacer 9.3|2413150|33|NZ_AP017377|CRT matches to position: 825934-825966, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgactttccgccagcttctg	Protospacer
*********************.*.*********

77. spacer 9.3|2413150|33|NZ_AP017377|CRT matches to position: 1472810-1472842, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

78. spacer 9.3|2413150|33|NZ_AP017377|CRT matches to position: 2053969-2054001, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

79. spacer 9.3|2413150|33|NZ_AP017377|CRT matches to position: 2687941-2687973, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP017377_7	7.1\|1951944\|26\|NZ_AP017377\|CRISPRCasFinder	1951944-1951969	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NZ_AP017377_3	3.1\|779336\|29\|NZ_AP017377\|CRISPRCasFinder	779336-779364	29	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	36494-36522	7	0.759

1. spacer 7.1|1951944|26|NZ_AP017377|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

tcgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

2. spacer 3.1|779336|29|NZ_AP017377|CRISPRCasFinder matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

cggggtcccaacatagagaaattggaacg	CRISPR spacer
ctaattccccacatagagaaattgcaact	Protospacer
* .. **** ************** ***

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

757417 : 765236

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244412.1\|757417_758473_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
WP_000149344.1\|758472_759159_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|759133_759607_-	DoxX family protein	NA	NA	NA	NA
WP_029051925.1\|759947_760388_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637687.1\|760667_761252_-	hypothetical protein	NA	NA	NA	NA
WP_001062970.1\|761350_762064_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|762067_762487_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|762488_763157_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604514.1\|763507_764101_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217785.1\|764084_765236_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_2

777208 : 791995

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|777208_778267_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197271.1\|778617_779160_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429014.1\|779839_780757_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
WP_001790641.1\|780847_780949_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|781026_782532_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|782872_783373_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|783392_784259_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|785059_785458_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|785420_787526_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|787643_788615_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|789128_789284_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|789322_790294_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|790280_791237_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616842.1\|791233_791995_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_3

912975 : 955121

Staphylococcus_phage(91.67%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000195429.1\|912975_914148_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001037045.1\|916092_916470_+	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001791893.1\|916817_916919_-	hypothetical protein	NA	NA	NA	NA
WP_001801861.1\|917041_917137_-	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001549059.1\|917339_917483_+\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_000070811.1\|918086_918470_+	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|918480_918657_+	hypothetical protein	NA	NA	NA	NA
WP_000809857.1\|918658_918844_+	hypothetical protein	NA	NA	NA	NA
WP_000494956.1\|918957_919599_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
WP_000195429.1\|919848_921021_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000414205.1\|921148_921700_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
WP_024937230.1\|921797_922142_-	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	6.9e-52	91.2
WP_000669046.1\|922182_922809_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.1e-79	82.7
WP_000070653.1\|922884_923880_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
WP_001795535.1\|923960_924611_-	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_011443643.1\|924913_925369_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
WP_000348360.1\|925527_927006_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
WP_000778523.1\|927010_928012_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
WP_000718107.1\|928008_928266_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000672014.1\|928331_928805_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_002868962.1\|928809_929556_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	7.1e-142	98.4
WP_000093392.1\|929930_930416_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
WP_000109906.1\|930551_932144_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_000933822.1\|932514_933708_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000366154.1\|933832_934741_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
WP_000453320.1\|934952_935786_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
WP_000623471.1\|937868_938222_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_001200542.1\|938218_938584_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000091445.1\|938839_939142_-	hypothetical protein	NA	NA	NA	NA
WP_000195429.1\|939367_940540_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001096494.1\|940733_941447_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_001168904.1\|941886_942522_-\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001030465.1\|942817_943261_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
WP_001153742.1\|943247_943691_-	competence protein ComK	NA	NA	NA	NA
WP_000671052.1\|943803_944274_-	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_000384171.1\|944472_944697_+	hypothetical protein	NA	NA	NA	NA
WP_001032833.1\|944972_945827_+	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000163235.1\|946121_946517_-	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
WP_000989121.1\|946534_947827_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_000221179.1\|947826_948141_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_001261677.1\|948663_950166_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000077344.1\|950646_951690_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.3e-197	99.4
WP_000493892.1\|951696_952329_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_001159022.1\|952339_953521_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_001008551.1\|953533_953998_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001196354.1\|954119_955121_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7

DBSCAN-SWA_4

958281 : 971010

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000764419.1\|958281_958845_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000526539.1\|958841_959795_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_001025061.1\|959904_961086_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_001549041.1\|961373_963791_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
WP_000836465.1\|963812_964124_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001050548.1\|964449_971010_+	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	2.0e-304	98.1

DBSCAN-SWA_5

1096624 : 1105667

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001005767.1\|1096624_1097629_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_001019172.1\|1097630_1098656_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001112045.1\|1098678_1099818_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001160682.1\|1099836_1100097_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_000749795.1\|1100371_1102651_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_000594993.1\|1102853_1105127_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
WP_000364542.1\|1105148_1105667_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_6

1174805 : 1183117

Caulobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217261.1\|1174805_1176605_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-54	36.0
WP_001283055.1\|1176828_1177935_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_000624584.1\|1178065_1178743_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_096377473.1\|1178745_1179846_+	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_001062180.1\|1179959_1181306_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	5.3e-55	33.7
WP_000924214.1\|1181315_1182206_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001213908.1\|1182331_1183117_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3

DBSCAN-SWA_7

1239573 : 1328505

104

Staphylococcus_phage(73.68%)

transposase,plate,tRNA,integrase,tail,capsid,holin,terminase,portal,head,protease

attL 1241040:1241057|attR 1287064:1287081

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000064078.1\|1239573_1240299_+	two-component system response regulator SrrA	W8CYM9	Bacillus_phage	3.5e-45	43.0
WP_000987769.1\|1240279_1242031_+	two-component system sensor histidine kinase SrrB	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
1241040:1241057	attL	NA	NA	NA	NA
WP_001797354.1\|1243196_1245224_+	hypothetical protein	B5WZK7	Staphylococcus_phage	6.9e-115	97.7
WP_000264751.1\|1245266_1246472_-\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
WP_001166484.1\|1246597_1247221_+	hypothetical protein	B7T0F3	Staphylococcus_virus	6.4e-104	99.0
WP_000705240.1\|1247366_1247549_-	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_000348133.1\|1247644_1248565_-	3'-5' exoribonuclease	B5WZL1	Staphylococcus_phage	2.5e-173	100.0
WP_000801423.1\|1248580_1249195_-	helix-turn-helix domain-containing protein	B5WZL2	Staphylococcus_phage	9.0e-111	100.0
WP_001030311.1\|1249366_1249594_+	hypothetical protein	B5WZL3	Staphylococcus_phage	3.3e-34	100.0
WP_001148559.1\|1249619_1250396_+	phage antirepressor KilAC domain-containing protein	M1RZB2	Staphylococcus_phage	1.5e-142	100.0
WP_001001383.1\|1250411_1250630_+	hypothetical protein	B5WZL5	Staphylococcus_phage	7.8e-33	100.0
WP_001025401.1\|1250679_1250925_+	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_001128433.1\|1250893_1251259_-	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001097552.1\|1251313_1251529_+	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
WP_001124198.1\|1251555_1251819_+	helix-turn-helix domain-containing protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
WP_001285948.1\|1251831_1251993_+	DUF1270 domain-containing protein	A9CR58	Staphylococcus_phage	1.1e-20	98.1
WP_000174994.1\|1252071_1252395_+	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	5.9e-53	100.0
WP_000985976.1\|1252409_1252772_+	hypothetical protein	A0A2I6PF03	Staphylococcus_phage	4.9e-56	100.0
WP_000762548.1\|1252768_1253935_+	DUF2800 domain-containing protein	M1T2Z7	Staphylococcus_phage	3.5e-220	99.5
WP_000645048.1\|1253960_1254518_+	DUF2815 family protein	A0A2I6PEP8	Staphylococcus_phage	1.8e-97	100.0
WP_075583731.1\|1254585_1256538_+	DNA polymerase	Q4ZCP5	Staphylococcus_virus	0.0e+00	99.4
WP_001164629.1\|1256550_1256736_+	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_000113974.1\|1256735_1257137_+	PVL family protein	A0A2I6PEL5	Staphylococcus_phage	1.2e-68	100.0
WP_000022728.1\|1257136_1257394_+	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
WP_000235324.1\|1257396_1257597_+	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
WP_000132191.1\|1257611_1257854_+	hypothetical protein	A0A2D1G5G2	Staphylococcus_phage	2.8e-39	97.5
WP_001065075.1\|1257868_1258117_+	DUF1024 family protein	Q9B0F3	Staphylococcus_virus	2.7e-37	97.6
WP_000185638.1\|1258109_1258637_+	dUTP pyrophosphatase	A7TWB1	Staphylococcus_phage	7.8e-95	100.0
WP_000195806.1\|1258673_1258910_+	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	3.1e-35	98.7
WP_000483477.1\|1258934_1259171_+	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
WP_024937089.1\|1259160_1259547_+	hypothetical protein	M9QX07	Staphylococcus_phage	2.6e-63	98.4
WP_024937088.1\|1259546_1259699_+	transcriptional regulator	A7TWI2	Staphylococcus_phage	1.4e-17	94.0
WP_000265258.1\|1259766_1259967_+	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000884864.1\|1260018_1262466_+	hypothetical protein	Q4ZCG0	Staphylococcus_virus	0.0e+00	99.3
WP_001802079.1\|1262568_1262673_-	hypothetical protein	Q4ZCF8	Staphylococcus_virus	1.0e-11	94.1
WP_000665203.1\|1262806_1263097_+	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
WP_001802078.1\|1263077_1264445_+	DEAD/DEAH box helicase	A0A2I6PE95	Staphylococcus_phage	2.3e-263	99.8
WP_000513699.1\|1264457_1264895_+	transcriptional regulator	A0A2I6PDC2	Staphylococcus_phage	4.6e-77	100.0
WP_000160689.1\|1265040_1265355_+	HNH endonuclease	A0A2I6PDC4	Staphylococcus_phage	2.5e-56	100.0
WP_024937087.1\|1265483_1265789_+\|terminase	P27 family phage terminase small subunit	A0A2I6PE27	Staphylococcus_phage	6.4e-49	99.0
WP_000153554.1\|1265778_1267470_+\|terminase	terminase large subunit	A0A1X9IGU0	Staphylococcus_phage	0.0e+00	99.8
WP_001100664.1\|1267474_1268713_+\|portal	phage portal protein	A0A2I6PER5	Staphylococcus_phage	6.9e-235	100.0
WP_000061866.1\|1268696_1269470_+\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
WP_001142734.1\|1269481_1270645_+\|capsid	phage major capsid protein	A0A2I6PEQ3	Staphylococcus_phage	1.2e-217	100.0
WP_000050973.1\|1270713_1270992_+\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_000395498.1\|1271003_1271336_+	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
WP_000110023.1\|1271332_1271734_+	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
WP_001023806.1\|1271734_1272130_+	DUF3168 domain-containing protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
WP_000807536.1\|1272164_1272806_+\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_024937086.1\|1272897_1273353_+	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	2.8e-77	99.3
WP_000589167.1\|1273410_1273761_+	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000438833.1\|1273802_1273961_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_024937085.1\|1273974_1280175_+\|tail	phage tail tape measure protein	A0A1X9IGU9	Staphylococcus_phage	0.0e+00	99.9
WP_001190527.1\|1280174_1280999_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	7.8e-158	99.6
WP_000384472.1\|1281007_1282591_+\|tail	phage tail protein	A0A2I6PEQ5	Staphylococcus_phage	2.1e-308	99.8
WP_000179858.1\|1282590_1282881_+	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
WP_000429558.1\|1282896_1284807_+	minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
WP_000067127.1\|1284806_1286273_+\|plate	phage baseplate upper protein	A0A2I6PES7	Staphylococcus_phage	1.5e-273	100.0
WP_001166596.1\|1286272_1286662_+	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	4.9e-62	99.2
WP_000916020.1\|1286654_1286819_+	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_000466784.1\|1286864_1287164_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
1287064:1287081	attR	NA	NA	NA	NA
WP_000339144.1\|1287299_1287602_+\|holin	phage holin	B7T0L0	Staphylococcus_virus	4.1e-48	100.0
WP_000909210.1\|1287612_1289067_+	N-acetylmuramoyl-L-alanine amidase	Q8SDN4	Staphylococcus_virus	7.5e-289	99.8
WP_000675478.1\|1289682_1290519_+	hypothetical protein	D2JLG6	Staphylococcus_phage	8.4e-152	100.0
WP_170267452.1\|1290895_1291111_+	hypothetical protein	A0ZS61	Staphylococcus_virus	1.5e-25	100.0
WP_000476873.1\|1291201_1292119_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000472939.1\|1292176_1293127_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001033757.1\|1293119_1293326_+	hypothetical protein	NA	NA	NA	NA
WP_000913219.1\|1293340_1294255_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001789947.1\|1294453_1294573_+	hypothetical protein	NA	NA	NA	NA
WP_001186912.1\|1294851_1295397_+	ECF transporter S component	NA	NA	NA	NA
WP_001151997.1\|1295502_1295751_-	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001163801.1\|1295858_1296812_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000902119.1\|1296801_1298181_+	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
WP_000069282.1\|1298333_1299794_+	elastin-binding protein EbpS	NA	NA	NA	NA
WP_001789943.1\|1299918_1300035_+	hypothetical protein	NA	NA	NA	NA
WP_001174260.1\|1300195_1301182_+	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_000681756.1\|1301296_1302265_-	asparaginase	NA	NA	NA	NA
WP_000644391.1\|1302341_1303001_+	(d)CMP kinase	NA	NA	NA	NA
WP_001789945.1\|1303031_1303148_+	hypothetical protein	NA	NA	NA	NA
WP_001789944.1\|1303264_1303456_+	hypothetical protein	NA	NA	NA	NA
WP_000133954.1\|1303712_1304888_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_000165530.1\|1305109_1306420_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000161738.1\|1306436_1307435_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_001043863.1\|1307605_1307878_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000450553.1\|1308308_1308881_+	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_000774684.1\|1308883_1309609_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_001096471.1\|1309610_1310570_+	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000442480.1\|1310661_1311111_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_000789522.1\|1311319_1311520_+	hypothetical protein	NA	NA	NA	NA
WP_096377475.1\|1311771_1312944_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_024937224.1\|1313238_1314405_+	chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	32.1
WP_000776323.1\|1314430_1315495_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_000245895.1\|1315504_1316803_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000389524.1\|1316809_1318054_+	hypothetical protein	NA	NA	NA	NA
WP_000004947.1\|1318067_1318643_+	YpiB family protein	G3MAV7	Bacillus_virus	2.7e-08	27.2
WP_000152734.1\|1318632_1319220_+	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_001827022.1\|1319291_1319972_+	zinc metallopeptidase	NA	NA	NA	NA
WP_000839926.1\|1320308_1320626_+	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_000690027.1\|1320866_1322009_+	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000361544.1\|1322013_1323216_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	3.2e-35	42.5
WP_000049919.1\|1323202_1324174_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000525078.1\|1324197_1326891_+	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000858789.1\|1327212_1328505_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0

DBSCAN-SWA_8

1510159 : 1517502

Staphylococcus_phage(85.71%)

transposase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000195429.1\|1510159_1511332_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_170943459.1\|1511509_1511998_-\|capsid	minor capsid protein	A0A2H4IYR8	uncultured_Caudovirales_phage	2.5e-23	76.7
WP_000956747.1\|1512139_1512391_-	hypothetical protein	NA	NA	NA	NA
WP_000477492.1\|1512519_1512624_-	hypothetical protein	NA	NA	NA	NA
WP_000006110.1\|1513135_1513321_-	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
WP_001788716.1\|1513748_1513859_-	hypothetical protein	NA	NA	NA	NA
WP_000195429.1\|1514250_1515423_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001002340.1\|1515891_1516098_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
WP_001789892.1\|1516391_1516616_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.3e-18	71.0
WP_001789891.1\|1517304_1517502_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4

DBSCAN-SWA_9

1689955 : 1769168

103

Staphylococcus_phage(75.34%)

transposase,plate,head,tRNA,capsid,holin,terminase,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000195429.1\|1689955_1691128_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000584398.1\|1691361_1691868_-	hypothetical protein	NA	NA	NA	NA
WP_000739563.1\|1692539_1692941_+	formyl peptide receptor-like 1 inhibitory protein	NA	NA	NA	NA
WP_001791789.1\|1692900_1692993_+	hypothetical protein	NA	NA	NA	NA
WP_000739209.1\|1693309_1693639_-	complement convertase inhibitor Ecb	NA	NA	NA	NA
WP_001791787.1\|1693832_1694000_-	hypothetical protein	NA	NA	NA	NA
WP_000049484.1\|1694127_1694631_-	metallophosphoesterase	NA	NA	NA	NA
WP_000659317.1\|1694623_1695211_-	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_001039659.1\|1695222_1696023_-	glutamate racemase	NA	NA	NA	NA
WP_000139712.1\|1696258_1697074_-	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_000818278.1\|1697073_1698840_-	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_000079317.1\|1698891_1699506_-	succinate dehydrogenase cytochrome B558	NA	NA	NA	NA
WP_096377483.1\|1699829_1701611_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_001788625.1\|1701776_1701872_+	hypothetical protein	NA	NA	NA	NA
WP_001018928.1\|1701934_1702249_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	6.6e-25	46.6
WP_001249285.1\|1702421_1704770_-	endonuclease MutS2	F2QAF8	Phaeocystis_pouchetii_virus	1.1e-15	25.3
WP_000161942.1\|1704779_1706492_-	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	8.9e-15	24.0
WP_000234068.1\|1706564_1707086_-	CvpA family protein	NA	NA	NA	NA
WP_000191455.1\|1707086_1707353_-	cell division protein ZapA	NA	NA	NA	NA
WP_001284258.1\|1707722_1708661_+	ribonuclease HIII	NA	NA	NA	NA
WP_024937191.1\|1708831_1711234_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_000003559.1\|1711233_1712292_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5
WP_000435374.1\|1712672_1713413_-	RNA methyltransferase	NA	NA	NA	NA
WP_001788617.1\|1713652_1713760_-	hypothetical protein	NA	NA	NA	NA
WP_000670950.1\|1713796_1714120_-	staphylobilin-forming heme oxygenase IsdG	NA	NA	NA	NA
WP_001242429.1\|1714138_1714873_-	class B sortase	NA	NA	NA	NA
WP_001548422.1\|1714934_1715903_-	iron ABC transporter permease	NA	NA	NA	NA
WP_001220199.1\|1715912_1716791_-	heme ABC transporter substrate-binding protein IsdE	NA	NA	NA	NA
WP_001246698.1\|1716787_1717864_-	hypothetical protein	NA	NA	NA	NA
WP_000789821.1\|1717863_1718547_-	heme uptake protein IsdC	NA	NA	NA	NA
WP_000160859.1\|1718755_1719808_+	LPXTG-anchored heme-scavenging protein IsdA	NA	NA	NA	NA
WP_001041586.1\|1720010_1721948_+	heme uptake protein IsdB	NA	NA	NA	NA
WP_096377485.1\|1722682_1724137_-	N-acetylmuramoyl-L-alanine amidase	I1W626	Staphylococcus_phage	9.8e-289	99.8
WP_000339141.1\|1724147_1724450_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000398862.1\|1724505_1724901_-	hypothetical protein	Q4ZBW9	Staphylococcus_virus	1.6e-68	100.0
WP_029052108.1\|1724906_1726079_-\|plate	BppU family phage baseplate upper protein	A9CRD3	Staphylococcus_phage	3.8e-198	100.0
WP_024937246.1\|1726091_1727990_-	glucosaminidase domain-containing protein	Q4ZDK5	Staphylococcus_virus	0.0e+00	97.8
WP_000466779.1\|1728126_1728426_-	DUF2951 domain-containing protein	A0A0F6N3M6	Staphylococcus_phage	1.3e-46	99.0
WP_001800921.1\|1728466_1728640_-	XkdX family protein	A0A059T7K6	Staphylococcus_phage	1.3e-27	100.0
WP_000705907.1\|1728643_1729021_-	DUF2977 domain-containing protein	Q4ZDT8	Staphylococcus_virus	8.1e-54	99.2
WP_000259591.1\|1729020_1730844_-\|plate	BppU family phage baseplate upper protein	A0A0H3U4S6	Staphylococcus_phage	0.0e+00	99.3
WP_000369020.1\|1730843_1732754_-	hypothetical protein	Q4ZDD6	Staphylococcus_virus	0.0e+00	99.2
WP_000156406.1\|1732768_1734670_-\|tail	phage tail protein	Q8SDT5	Staphylococcus_phage	0.0e+00	100.0
WP_000350680.1\|1734678_1735626_-\|tail	phage tail family protein	Q8SDT6	Staphylococcus_phage	2.1e-183	100.0
WP_096377487.1\|1735638_1739103_-	hypothetical protein	Q4ZDU6	Staphylococcus_virus	1.0e-259	93.4
WP_000105584.1\|1739119_1739464_-	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
WP_001100163.1\|1739493_1739859_-	hypothetical protein	Q8SDT9	Staphylococcus_phage	2.8e-59	100.0
WP_086045425.1\|1739920_1740502_-\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	7.0e-105	99.5
WP_000188649.1\|1740520_1740904_-	hypothetical protein	A0A0F6N3L1	Staphylococcus_phage	1.5e-68	100.0
WP_096377489.1\|1740915_1741263_-	HK97 gp10 family phage protein	A0A0F6N3F5	Staphylococcus_phage	9.1e-60	99.1
WP_001268312.1\|1741262_1741565_-	hypothetical protein	A4ZFB6	Staphylococcus_virus	1.1e-50	100.0
WP_000208959.1\|1741561_1741894_-\|head,tail	phage head-tail connector protein	E0Y3L2	Staphylococcus_virus	7.1e-54	100.0
WP_001114085.1\|1741902_1742190_-	hypothetical protein	S4V6D9	Staphylococcus_phage	4.7e-46	100.0
WP_000438512.1\|1742211_1743186_-\|capsid	phage major capsid protein	S4SVE6	Staphylococcus_phage	2.2e-183	100.0
WP_000354309.1\|1743199_1743814_-	DUF4355 domain-containing protein	I1W646	Staphylococcus_phage	2.9e-40	100.0
WP_000072207.1\|1743948_1744119_-	hypothetical protein	Q4ZDF2	Staphylococcus_virus	3.3e-23	100.0
WP_001668926.1\|1744191_1745187_-\|capsid	minor capsid protein	B2ZYY2	Staphylococcus_phage	3.4e-184	100.0
WP_096377491.1\|1745193_1746732_-\|portal	phage portal protein	S4V6D8	Staphylococcus_phage	2.9e-291	99.2
WP_000169944.1\|1746742_1748020_-\|terminase	PBSX family phage terminase large subunit	Q8SDU9	Staphylococcus_phage	3.0e-249	100.0
WP_001003271.1\|1748006_1748447_-\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	4.8e-74	100.0
WP_000162699.1\|1748634_1749057_-	RinA family phage transcriptional activator	Q8SDV1	Staphylococcus_phage	1.6e-74	100.0
WP_000989998.1\|1749080_1749227_-	hypothetical protein	A0A059T5A8	Staphylococcus_phage	2.2e-15	100.0
WP_024937262.1\|1749227_1749401_-	transcriptional regulator	A1KX88	Staphylococcus_virus	8.3e-22	98.2
WP_000195791.1\|1749397_1749604_-	DUF1381 domain-containing protein	A0A0H4IPW6	Staphylococcus_phage	4.5e-30	100.0
WP_001282070.1\|1749600_1749846_-	hypothetical protein	A0A0H4ITX2	Staphylococcus_phage	2.0e-37	100.0
WP_000185706.1\|1749882_1750413_-	dUTP diphosphatase	I1W653	Staphylococcus_phage	9.2e-96	100.0
WP_000097971.1\|1750405_1750612_-	Lar family restriction alleviation protein	A0A1W6JNF7	Staphylococcus_phage	1.6e-24	81.2
WP_024937263.1\|1750611_1750854_-	DUF1024 family protein	E9LT37	Staphylococcus_phage	3.7e-36	97.5
WP_096377492.1\|1750846_1751257_-	acetyltransferase	A0A1X9H0B8	Staphylococcus_phage	6.3e-60	86.8
WP_031868690.1\|1751253_1751787_-	hypothetical protein	A0A1X9H0D4	Staphylococcus_phage	8.5e-81	96.1
WP_000979209.1\|1751783_1752131_-	hypothetical protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
WP_024937270.1\|1752127_1752532_-	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	4.6e-71	99.2
WP_024937271.1\|1752534_1752741_-	hypothetical protein	A0A0N9BAW9	Staphylococcus_phage	6.6e-34	98.5
WP_001837466.1\|1752755_1752998_-	hypothetical protein	E9LT32	Staphylococcus_phage	1.7e-41	100.0
WP_024937272.1\|1753001_1753370_-	hypothetical protein	A0A0H4J337	Staphylococcus_phage	1.7e-51	95.1
WP_001187242.1\|1753370_1753556_-	DUF3113 family protein	W5R8N4	Staphylococcus_phage	1.4e-27	100.0
WP_000049784.1\|1753560_1753965_-	DUF1064 domain-containing protein	A7TWN5	Staphylococcus_phage	7.1e-72	100.0
WP_001123673.1\|1753975_1754197_-	DUF3269 family protein	A7TWN4	Staphylococcus_phage	1.3e-35	100.0
WP_000237153.1\|1754209_1754371_-	hypothetical protein	D2JGK6	Staphylococcus_phage	4.5e-22	100.0
WP_031873668.1\|1754364_1755144_-	ATP-binding protein	Q9G022	Staphylococcus_virus	1.0e-143	99.2
WP_024937256.1\|1755154_1755925_-	conserved phage C-terminal domain-containing protein	W5R8N2	Staphylococcus_phage	6.9e-116	99.2
WP_000371252.1\|1755989_1756838_+	DUF4393 domain-containing protein	W5R9J9	Staphylococcus_phage	3.8e-160	100.0
WP_001199445.1\|1756944_1757616_-	hypothetical protein	W5R8I8	Staphylococcus_phage	5.2e-128	100.0
WP_000704705.1\|1757628_1758180_-	single-stranded DNA-binding protein	Q4ZBM4	Staphylococcus_phage	3.4e-101	100.0
WP_024937264.1\|1758209_1758983_-	AAA family ATPase	A0EWP9	Staphylococcus_virus	8.1e-141	99.6
WP_000002519.1\|1758982_1759462_-	siphovirus Gp157 family protein	A0ZS19	Staphylococcus_virus	4.0e-82	100.0
WP_024937265.1\|1759476_1759737_-	DUF1108 family protein	Q4ZDA1	Staphylococcus_virus	2.6e-43	98.8
WP_000066026.1\|1759830_1759992_-	DUF1270 family protein	C8CGY5	Staphylococcus_phage	2.5e-20	100.0
WP_000230552.1\|1759984_1760122_-	hypothetical protein	S4SX85	Staphylococcus_phage	3.2e-16	100.0
WP_000395457.1\|1760171_1760402_+	hypothetical protein	R4IG40	Staphylococcus_phage	2.3e-35	100.0
WP_000390105.1\|1760605_1760800_-	hypothetical protein	E9LT75	Staphylococcus_phage	1.2e-29	100.0
WP_001002760.1\|1760816_1761581_-	phage antirepressor Ant	R4IFK0	Staphylococcus_phage	2.7e-141	99.6
WP_000108122.1\|1761580_1761775_-	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	1.1e-25	100.0
WP_001055143.1\|1762037_1762370_+	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	4.1e-57	100.0
WP_000775187.1\|1762386_1763061_+	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	4.9e-126	100.0
WP_000661437.1\|1763088_1763814_+	PH domain-containing protein	A0A0F6N4L7	Staphylococcus_phage	9.9e-125	100.0
WP_000392183.1\|1763845_1764778_+	hypothetical protein	A0EX19	Staphylococcus_virus	6.7e-174	100.0
WP_000337827.1\|1764757_1764937_-	hypothetical protein	Q4ZBP0	Staphylococcus_phage	3.7e-25	100.0
WP_000861313.1\|1765045_1766431_+	recombinase family protein	I1W625	Staphylococcus_phage	2.5e-265	100.0
WP_000290472.1\|1766547_1766721_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_000872158.1\|1766800_1767358_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_000843611.1\|1767484_1768624_+	nucleotidyltransferase	NA	NA	NA	NA
WP_000401377.1\|1768685_1769168_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2

DBSCAN-SWA_10

1820761 : 1829234

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000238664.1\|1820761_1821328_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1
WP_000030812.1\|1821330_1822359_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000483713.1\|1822351_1823836_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000032727.1\|1823814_1826004_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000666799.1\|1825996_1826668_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_024937102.1\|1826669_1826933_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000174053.1\|1826932_1827637_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_001010412.1\|1827640_1828765_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000861572.1\|1828751_1829234_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7

DBSCAN-SWA_11

1849220 : 1881462

Enterococcus_phage(16.67%)

transposase,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001088780.1\|1849220_1850402_+\|protease	cysteine protease staphopain B	NA	NA	NA	NA
WP_000284457.1\|1850439_1850769_+	staphostatin B	NA	NA	NA	NA
WP_000184947.1\|1851007_1851829_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000150195.1\|1851821_1852625_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000526687.1\|1852611_1854285_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_000190623.1\|1854271_1855633_-	isochorismate synthase MenF	NA	NA	NA	NA
WP_000070966.1\|1855814_1856753_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000620955.1\|1856804_1857356_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000867357.1\|1857520_1857736_+	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	1.5e-07	49.1
WP_001790177.1\|1857799_1857931_+	hypothetical protein	NA	NA	NA	NA
WP_001081351.1\|1857976_1858936_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000766009.1\|1859412_1859769_+	DoxX family protein	NA	NA	NA	NA
WP_000719184.1\|1859857_1861339_-	glycosyltransferase	NA	NA	NA	NA
WP_000410720.1\|1861344_1861632_-	hypothetical protein	NA	NA	NA	NA
WP_001795544.1\|1861910_1862201_+	hypothetical protein	NA	NA	NA	NA
WP_000571178.1\|1862288_1862930_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-19	33.7
WP_000668623.1\|1862926_1863247_-	YxeA family protein	NA	NA	NA	NA
WP_000870806.1\|1863249_1865214_-\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_001790097.1\|1865257_1865530_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_001790623.1\|1865539_1865641_-	hypothetical protein	NA	NA	NA	NA
WP_001033867.1\|1866557_1867160_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000214898.1\|1867174_1867351_-	YkvS family protein	NA	NA	NA	NA
WP_000668820.1\|1867549_1868536_+	lipoate--protein ligase	NA	NA	NA	NA
WP_000876826.1\|1868616_1868835_-	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000287265.1\|1869044_1869614_+	competence protein ComK	NA	NA	NA	NA
WP_000414177.1\|1870100_1871612_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000021864.1\|1871750_1873109_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000455278.1\|1873125_1875450_-\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.4
WP_000928413.1\|1875668_1876472_-	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_001049959.1\|1876773_1878336_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	4.9e-36	28.2
WP_001795833.1\|1878335_1878596_-	YueH family protein	NA	NA	NA	NA
WP_000340118.1\|1878579_1880061_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_000195429.1\|1880289_1881462_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0

DBSCAN-SWA_12

1903335 : 1983810

Staphylococcus_phage(73.53%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000448934.1\|1903335_1904325_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_096377495.1\|1905231_1906404_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	7.7e-135	99.6
WP_000593417.1\|1906591_1907554_-	ABC transporter permease	NA	NA	NA	NA
WP_000427770.1\|1907546_1908527_-	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-16	31.6
WP_001067038.1\|1908529_1909516_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.0e-15	30.4
WP_000517187.1\|1909566_1911282_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_031906687.1\|1911493_1913149_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000786734.1\|1913167_1914109_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.3e-23	32.9
WP_000140050.1\|1914098_1915181_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.4e-19	28.8
WP_000829632.1\|1915197_1916268_-	ABC transporter permease	NA	NA	NA	NA
WP_000521533.1\|1916267_1917194_-	ABC transporter permease	NA	NA	NA	NA
WP_000915155.1\|1917436_1917808_+	DUF3899 domain-containing protein	NA	NA	NA	NA
WP_000081240.1\|1917862_1919107_-	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_001100525.1\|1919118_1920060_-	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_000682089.1\|1920354_1920540_+	YjzD family protein	NA	NA	NA	NA
WP_000769689.1\|1920796_1921231_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000695342.1\|1921541_1922057_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_000195429.1\|1922558_1923731_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000404422.1\|1924483_1925125_-	L-threonylcarbamoyladenylate synthase	NA	NA	NA	NA
WP_001047066.1\|1926362_1927232_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000353955.1\|1927290_1929900_-	ATP-dependent chaperone ClpB	A0A223W0B1	Agrobacterium_phage	5.5e-117	34.3
WP_001044214.1\|1930102_1931917_-	acetyltransferase	B5WZU0	Pseudomonas_phage	1.1e-36	33.9
WP_000390575.1\|1932452_1932761_-	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_001182436.1\|1932874_1933699_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_001124525.1\|1933750_1935067_+	CoA-disulfide reductase	NA	NA	NA	NA
WP_000902817.1\|1935237_1935627_-	YisL family protein	NA	NA	NA	NA
WP_000670752.1\|1935955_1936858_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_000154914.1\|1937023_1940677_-	helicase-exonuclease AddAB subunit AddA	A7KV33	Bacillus_phage	3.5e-24	24.5
WP_000172342.1\|1940677_1944154_-	helicase-exonuclease AddAB subunit AddB	NA	NA	NA	NA
WP_000711486.1\|1944313_1944889_-	signal peptidase I	NA	NA	NA	NA
WP_000758215.1\|1944904_1945429_-	signal peptidase I	NA	NA	NA	NA
WP_000007967.1\|1945433_1946009_-	TVP38/TMEM64 family protein	NA	NA	NA	NA
WP_000148855.1\|1946333_1947665_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_000660045.1\|1948015_1949221_+	argininosuccinate synthase	NA	NA	NA	NA
WP_000066053.1\|1949210_1950590_+	argininosuccinate lyase	NA	NA	NA	NA
WP_000185319.1\|1950831_1951761_+	glycerophosphodiester phosphodiesterase	A0A220BYK6	Staphylococcus_phage	3.7e-39	37.9
WP_000138487.1\|1952149_1953394_-	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_000167314.1\|1953502_1954693_-	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	1.3e-33	29.7
WP_000838037.1\|1955000_1956128_-	NADH-dependent flavin oxidoreductase	NA	NA	NA	NA
WP_001067294.1\|1956489_1956867_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_000195429.1\|1957235_1958408_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000072576.1\|1958741_1959941_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	5.5e-229	99.7
WP_009559872.1\|1959933_1961490_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.2e-287	99.2
WP_001791797.1\|1961653_1961788_-	hypothetical protein	NA	NA	NA	NA
WP_001038688.1\|1961852_1962572_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_001038759.1\|1962722_1963439_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
WP_011447030.1\|1963540_1963648_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1963596_1964316_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038867.1\|1964436_1965156_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
WP_001039447.1\|1965213_1965936_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
WP_054105219.1\|1966060_1966753_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.7e-127	100.0
WP_000195429.1\|1966801_1967974_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001092763.1\|1969063_1969630_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_000586140.1\|1970103_1970802_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_000581552.1\|1970798_1971560_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|1971556_1972249_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|1972271_1973645_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|1973654_1974173_-	flavoprotein	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000566596.1\|1974188_1975433_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_001092605.1\|1975425_1978419_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.3
WP_000416756.1\|1978483_1978627_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_000416759.1\|1979364_1979508_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000782464.1\|1979749_1980733_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000473596.1\|1980734_1981670_-	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
WP_001790220.1\|1982469_1983009_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	2.0e-61	76.8
WP_000206350.1\|1983021_1983810_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

DBSCAN-SWA_13

2066809 : 2166936

118

Staphylococcus_phage(87.34%)

head,tRNA,integrase,capsid,holin,terminase,portal,tail,protease

attL 2128662:2128679|attR 2153053:2153070

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000027927.1\|2066809_2068267_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|2068268_2068571_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957015.1\|2068937_2070476_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831698.1\|2070564_2071764_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774565.1\|2071776_2073780_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
WP_000992921.1\|2073783_2075976_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272070.1\|2075972_2076665_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|2076836_2077139_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|2077247_2078543_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827748.1\|2079403_2080570_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434933.1\|2080600_2080927_+	staphostatin A	NA	NA	NA	NA
WP_000669862.1\|2081218_2081392_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2081372_2081975_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040873.1\|2082245_2083067_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.8e-69	52.7
WP_000284431.1\|2083059_2084529_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.5e-108	45.1
WP_000897635.1\|2084712_2085789_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177817.1\|2085808_2086603_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2086674_2086782_+	hypothetical protein	NA	NA	NA	NA
WP_000323161.1\|2086792_2088355_-	SLC13 family permease	NA	NA	NA	NA
WP_000275730.1\|2088559_2089657_-	pectate lyase	U5PWM6	Bacillus_phage	1.9e-47	34.6
WP_000149686.1\|2090028_2090589_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_024937195.1\|2090641_2091571_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2091765_2091939_-	hypothetical protein	NA	NA	NA	NA
WP_001021214.1\|2091990_2093370_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181322.1\|2093489_2094518_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2094787_2095189_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2095761_2095935_-	hypothetical protein	NA	NA	NA	NA
WP_001188077.1\|2096385_2097426_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1\|2097482_2098325_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2098321_2098879_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2098938_2099463_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2099583_2100147_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221651.1\|2100212_2100953_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|2100952_2101825_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645727.1\|2101821_2102502_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991302.1\|2102502_2103399_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|2103395_2103776_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2104039_2104216_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2104458_2104557_-	hypothetical protein	NA	NA	NA	NA
WP_001068542.1\|2104756_2106043_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001549158.1\|2106631_2108386_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669791.1\|2109343_2109523_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	1.4e-24	98.3
WP_001791826.1\|2109833_2110094_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|2110146_2110497_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_000920038.1\|2111993_2112485_-	staphylokinase	A0A1W6JQ12	Staphylococcus_phage	4.7e-86	99.4
WP_000861038.1\|2112675_2113431_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000611508.1\|2113442_2113697_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	1.5e-40	98.8
WP_031762631.1\|2113748_2113856_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1\|2113908_2114085_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_000750412.1\|2114193_2114967_-	staphylococcal enterotoxin type A	A0A1X9H080	Staphylococcus_phage	1.1e-145	100.0
WP_000340977.1\|2115339_2115714_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001262621.1\|2115769_2116057_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
WP_001000058.1\|2116102_2116255_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
WP_000582173.1\|2116247_2120030_-	hypothetical protein	A0A1X9H096	Staphylococcus_phage	0.0e+00	99.7
WP_000567408.1\|2120045_2121530_-\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
WP_001795393.1\|2121526_2126056_-\|tail	phage tail tape measure protein	A0A1X9H084	Staphylococcus_phage	0.0e+00	100.0
WP_001549167.1\|2126112_2126250_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
WP_001096355.1\|2126300_2126651_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_072050172.1\|2126700_2126925_-	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	8.8e-32	98.6
WP_000268741.1\|2126966_2127611_-\|tail	phage tail protein	W5R9H4	Staphylococcus_phage	6.5e-120	100.0
WP_000565498.1\|2127611_2128019_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114225.1\|2128015_2128420_-	HK97 gp10 family phage protein	A0A2I6PDJ6	Staphylococcus_phage	4.3e-69	100.0
WP_000755150.1\|2128416_2128779_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2128662:2128679	attL	NA	NA	NA	NA
WP_000150936.1\|2128762_2129047_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|2129036_2129321_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154555.1\|2129340_2130486_-\|capsid	phage major capsid protein	A0A1X9H072	Staphylococcus_phage	5.6e-215	100.0
WP_000861914.1\|2130509_2131247_-\|protease	Clp protease ClpP	C8CH20	Staphylococcus_phage	2.3e-129	100.0
WP_000025274.1\|2131230_2132418_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1\|2132433_2134095_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|2134091_2134436_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988333.1\|2134566_2134866_-	HNH endonuclease	A0A1W6JPL7	Staphylococcus_phage	2.7e-52	100.0
WP_000590126.1\|2135097_2135514_-	hypothetical protein	A0A1X9H0U8	Staphylococcus_phage	2.9e-76	100.0
WP_000265039.1\|2135541_2135742_-	DUF1514 family protein	R9QT57	Staphylococcus_phage	1.4e-28	98.5
WP_000595265.1\|2135741_2135891_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000195820.1\|2135887_2136094_-	DUF1381 domain-containing protein	A0A1X9H0C2	Staphylococcus_phage	1.3e-21	100.0
WP_001066444.1\|2136130_2136667_-	dUTP diphosphatase	A0A1X9H0S5	Staphylococcus_phage	1.4e-96	100.0
WP_000197967.1\|2136659_2137070_-	hypothetical protein	C8CH13	Staphylococcus_phage	2.3e-70	100.0
WP_001105598.1\|2137066_2137576_-	hypothetical protein	A0A1X9H0D4	Staphylococcus_phage	3.2e-93	100.0
WP_000982711.1\|2137572_2138022_-	hypothetical protein	A0A2I6PDH2	Staphylococcus_phage	2.1e-80	99.3
WP_000131366.1\|2138086_2138329_-	hypothetical protein	A0EWX8	Staphylococcus_phage	3.9e-41	100.0
WP_000101274.1\|2138332_2138701_-	hypothetical protein	W5RAK8	Staphylococcus_phage	8.2e-51	100.0
WP_000401964.1\|2138713_2139118_-	RusA family crossover junction endodeoxyribonuclease	A0A0E3XBN4	Staphylococcus_phage	1.4e-72	100.0
WP_000338528.1\|2139126_2139345_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_024937183.1\|2139351_2140236_-	DnaD domain protein	I1W658	Staphylococcus_phage	9.0e-136	98.6
WP_024937184.1\|2140265_2140736_-	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	1.3e-77	95.5
WP_071621397.1\|2140736_2141354_-	MBL fold metallo-hydrolase	S4SWA4	Staphylococcus_phage	9.1e-87	100.0
WP_000138481.1\|2141434_2142355_-	recombinase RecT	A0A1V0E5D7	Staphylococcus_phage	1.0e-166	100.0
WP_000700565.1\|2142356_2144300_-	AAA family ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	99.1
WP_001205732.1\|2144308_2144572_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291489.1\|2144580_2144841_-	DUF1108 family protein	A0A1W6JQ03	Staphylococcus_phage	7.6e-43	100.0
WP_000066020.1\|2144933_2145095_-	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
WP_001120197.1\|2145091_2145412_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000275058.1\|2145470_2146103_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
WP_000939496.1\|2146117_2146258_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
WP_000388066.1\|2146288_2146483_-	hypothetical protein	A0A1X9H0A2	Staphylococcus_phage	1.5e-19	100.0
WP_001148618.1\|2146499_2147252_-	phage antirepressor KilAC domain-containing protein	A0A1X9H0A0	Staphylococcus_phage	8.7e-140	100.0
WP_000351243.1\|2147308_2147848_+	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
WP_000435341.1\|2147871_2148132_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000548578.1\|2148144_2148384_-	helix-turn-helix transcriptional regulator	G4KNM9	Staphylococcus_phage	2.3e-38	100.0
WP_000094093.1\|2148554_2149262_+	helix-turn-helix transcriptional regulator	G4KNM8	Staphylococcus_phage	7.7e-130	100.0
WP_001049399.1\|2149273_2149429_+	hypothetical protein	A0A2I6PDR9	Staphylococcus_phage	6.3e-21	100.0
WP_001089804.1\|2149415_2149601_+	hypothetical protein	A0A2I6PDS4	Staphylococcus_phage	2.3e-25	100.0
WP_000705238.1\|2149800_2149968_+	hypothetical protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
WP_000391618.1\|2150107_2150647_+	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	9.0e-14	33.1
WP_000857198.1\|2150819_2151857_+\|integrase	site-specific integrase	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
WP_000595324.1\|2152975_2153992_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	1.1e-25	29.0
2153053:2153070	attR	NA	NA	NA	NA
WP_000791407.1\|2154013_2155069_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
WP_000206638.1\|2155503_2156727_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_000812008.1\|2157098_2157944_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000825510.1\|2158005_2158917_-	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001045079.1\|2159077_2160385_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000022887.1\|2161237_2161681_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001797573.1\|2161845_2162223_-	hypothetical protein	NA	NA	NA	NA
WP_001293058.1\|2162540_2163131_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.1e-97	95.8
WP_000128898.1\|2163127_2163340_-	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-23	74.3
WP_000240645.1\|2164041_2165658_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
WP_000917289.1\|2165733_2166018_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000197635.1\|2166192_2166936_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_AP017377.1|WP_000416756.1|1978483_1978627_-|gallidermin/nisin-family-lantibiotic

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_AP017377.1|WP_000416756.1|1978483_1978627_-|gallidermin/nisin-family-lantibiotic

1978483_1978627_-

47 aa aa

1903335-1983810

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_AP017377_5	Orphan	5.2\|975994\|18\|NZ_AP017377\|CRT	975994-976011	18	1932430-1932413	0

1. spacer 5.2|975994|18|NZ_AP017377|CRT matches to NZ_AP017377 position: 1932430-1932413, mismatch: 0

aatttcttttcgaaattc	CRISPR spacer
aatttcttttcgaaattc	Protospacer
******************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP017377

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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