CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP017920	Thermus thermophilus strain TMY	6 crisprs	cmr3gr5,cmr5gr11,cmr4gr7,cmr6gr7,csm3gr7,cas1,cas4,cas6,cas8b1,cas7,cas5,cas2,DEDDh,csa3,TnpB_regular.1,cas3,cas10,cmr1gr7,csx1,csm2gr11,csm5gr7	0	10	3	0
NZ_AP017921	Thermus thermophilus strain TMY plasmid pTMY, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP017920_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017920_1

96922-99040

TypeIII-B,TypeI-B

Consensus_repeat	Method
GTTTCAAACCCTCATAGGTACGGTCAAAAC	PILER-CR
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CRISPRCasFinder
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CRT

31 spacers

csm3gr7,cmr6gr7,cmr4gr7,cmr5gr11,cmr3gr5,cas1,cas4,cas6,cas8b1,cas7,cas5,cas2

The CRISPR arrays of NZ_AP017920_1

>merge|NZ_AP017920|1|96922-99040|PILER-CR,CRISPRCasFinder,CRT
GTTTCGAACCCTCATAGGTACGGTCAAAACTAGGAGCCGCACGGCGTAAACCCCGGGTACGGCTTGGGGTTTCAAACCCTCATAGGTACGGTCAAAACTGGGAGCGGCGGCGTAGGCGGGCAGTATGGCGGCGGACTTGTTTCAAACCCTCATAGGTACGGTCAAAACTCCGGGGCGGTGGTGTAGTTGGCCCTTTGAGGTCGCTTGGTTTCAAACCCTCATAGGTACGGTCAAAACAAACGCCCCGCTCAGCGCCCTGAGCGCCTGCTCGGCCTGTTTCAAACCCTCATAGGTACGGTCAAAACCTTTAGTCAGCTCCGCACCACCCTGGACCCGCTTCTGTTTCAAACCCTCATAGGTACGGTCAAAACAGGAAAGAATTGCACGGTGGCTGAACGAGCGGAACGTGTTTCAAACCCTCATAGGTACGGTCAAAACTTCCCGGCGCAGGTCCTCGGAGGTACCGAGCGCGTCAAACGTTTCAAACCCTCATAGGTACGGTCAAAACGCCCCGAGTTCCAGGCGTACGGCGGCAGGCAGAAAAGTTTCAAACCCTCATAGGTACGGTCAAAACGGTACATCTCTTGGGCTCAAAGGGTGGTAAAGCGCCGTTTCAAACCCTCATAGGTACGGTCAAAACATGGCCCTGCCGGAGCTTCGGCGGGCCATTAGGGAGGTGTTTCAAACCCTCATAGGTACGGTCAAAACTTTTCGAGGGGGGAGAAATGAAGTTGAGAGACTATGTTTCAAACCCTCATAGGTACGGTCAAAACCCGCAAGTACGTGGTGAGCGGGCTGCAGGTGAGCCCGGGGTTTCAAACCCTCATAGGTACGGTCAAAACTCTCACCCCCTTTCAACCTCATACGACTGCCATTATAGGTTTCAAACCCTCATAGGTACGGTCAAAACATTTCCCGGGCATGGAGCGTATGCAGGGCTGTTCGCCTGGTTTCAAACCCTCATAGGTACGGTCAAAACCCGCCCCGCACAAAGGGCTCAAGGATGAGGGAGAAGAAGTTTCAAACCCTCATAGGTACGGTCAAAACCCTCCCGGGCTAACAGCGTACGGGGTGGGCCACCCCGTGTTTCAAACCCTCATAGGTACGGTCAAAACCCCGGCTCGGCATACGCCGTTCCGAGGCTCTAGGTTTCAAACCCTCATAGGTACGGTCAAAACCAGGGAAGCGCAGACGAAGTTAGCCCAGACGAACCAAGTTTCAAACCCTCATAGGTACGGTCAAAACCACGGGTTAGGGCGCGGCCGCAAAACTCCCGGAGTATGTTTCAAACCCTCATAGGTACGGTCAAAACCGCCCACCTGTGGCTTGGGGGTCCAGATGGACCAGAAAGTTTCAAACCCTCATAGGTACGGTCAAAACGCGTGCGGGACCTGAGCGAGCTGGACGTCCCTTGGGAGTTTCAAACCCTCATAGGTACGGTCAAAACCTTCCCCCTCCACGAGCCCCACCAAACGACAGGCCTCAGGTTTCAAACCCTCATAGGTACGGTCAAAACCCCGATGGCCTCCTCCAGGGTGTAGGGGCCTTCCCGCGTTTCAAACCCTCATAGGTACGGTCAAAACTGAGAGGGGGGTAGACCTCCTTCACCTCCTCGCGTTTCAAACCCTCATAGGTACGGTCAAAACACAACTGGAGGGCGGTGGTTATTACCGATGAAGAGGGGTTTCAAACCCTCATAGGTACGGTCAAAACGCGTGTATGGCGTCCCCAGCGTGGCGGTGGCAATCAGGGGTTTCAAACCCTCATAGGTACGGTCAAAACGGGCGAGGCGCATCCTCGTCCCTGAGGGCGGGTTTTAGTTTCAAACCCTCATAGGTACGGTCAAAACCGGGGCGTATGTGGCCGACAACCCCTCGGAGGAGGCCATGTTTCAAACCCTCATAGGTACGGTCAAAACCAAAAAATCGGGGGGATCACGTTCCATTTTCTGTCCAGGTTTCAAACCCTCATAGGTACGGTCAAAACTCGCCCGGGCCCACTCCTCCTCCGTCCGCCTGAGGAGGTTTCAAACCCTCATAGGTACGGTCAAAACGCCACCGCGTGCGGGTAGCCCTGCGCTTGGAGACGGGTTTCAAACCCTCATAGGTACGGTCAAAAC

>NZ_AP017920|1|1|96922-99040|PILER-CR
GTTTCGAACCCTCATAGGTACGGTCAAAAC	TAGGAGCCGCACGGCGTAAACCCCGGGTACGGCTTGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TGGGAGCGGCGGCGTAGGCGGGCAGTATGGCGGCGGACTT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCCGGGGCGGTGGTGTAGTTGGCCCTTTGAGGTCGCTTG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	AAACGCCCCGCTCAGCGCCCTGAGCGCCTGCTCGGCCT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CTTTAGTCAGCTCCGCACCACCCTGGACCCGCTTCT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	AGGAAAGAATTGCACGGTGGCTGAACGAGCGGAACGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TTCCCGGCGCAGGTCCTCGGAGGTACCGAGCGCGTCAAAC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCCCCGAGTTCCAGGCGTACGGCGGCAGGCAGAAAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GGTACATCTCTTGGGCTCAAAGGGTGGTAAAGCGCC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ATGGCCCTGCCGGAGCTTCGGCGGGCCATTAGGGAGGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TTTTCGAGGGGGGAGAAATGAAGTTGAGAGACTAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCGCAAGTACGTGGTGAGCGGGCTGCAGGTGAGCCCGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCTCACCCCCTTTCAACCTCATACGACTGCCATTATAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ATTTCCCGGGCATGGAGCGTATGCAGGGCTGTTCGCCTG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCGCCCCGCACAAAGGGCTCAAGGATGAGGGAGAAGAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCTCCCGGGCTAACAGCGTACGGGGTGGGCCACCCCGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCCGGCTCGGCATACGCCGTTCCGAGGCTCTAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CAGGGAAGCGCAGACGAAGTTAGCCCAGACGAACCAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CACGGGTTAGGGCGCGGCCGCAAAACTCCCGGAGTAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CGCCCACCTGTGGCTTGGGGGTCCAGATGGACCAGAAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCGTGCGGGACCTGAGCGAGCTGGACGTCCCTTGGGA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CTTCCCCCTCCACGAGCCCCACCAAACGACAGGCCTCAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCCGATGGCCTCCTCCAGGGTGTAGGGGCCTTCCCGC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TGAGAGGGGGGTAGACCTCCTTCACCTCCTCGC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ACAACTGGAGGGCGGTGGTTATTACCGATGAAGAGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCGTGTATGGCGTCCCCAGCGTGGCGGTGGCAATCAGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GGGCGAGGCGCATCCTCGTCCCTGAGGGCGGGTTTTA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CGGGGCGTATGTGGCCGACAACCCCTCGGAGGAGGCCAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CAAAAAATCGGGGGGATCACGTTCCATTTTCTGTCCAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCGCCCGGGCCCACTCCTCCTCCGTCCGCCTGAGGAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCCACCGCGTGCGGGTAGCCCTGCGCTTGGAGACGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC

>NZ_AP017920|1|1|96922-99040|CRISPRCasFinder
GTTTCGAACCCTCATAGGTACGGTCAAAAC	TAGGAGCCGCACGGCGTAAACCCCGGGTACGGCTTGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TGGGAGCGGCGGCGTAGGCGGGCAGTATGGCGGCGGACTT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCCGGGGCGGTGGTGTAGTTGGCCCTTTGAGGTCGCTTG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	AAACGCCCCGCTCAGCGCCCTGAGCGCCTGCTCGGCCT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CTTTAGTCAGCTCCGCACCACCCTGGACCCGCTTCT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	AGGAAAGAATTGCACGGTGGCTGAACGAGCGGAACGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TTCCCGGCGCAGGTCCTCGGAGGTACCGAGCGCGTCAAAC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCCCCGAGTTCCAGGCGTACGGCGGCAGGCAGAAAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GGTACATCTCTTGGGCTCAAAGGGTGGTAAAGCGCC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ATGGCCCTGCCGGAGCTTCGGCGGGCCATTAGGGAGGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TTTTCGAGGGGGGAGAAATGAAGTTGAGAGACTAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCGCAAGTACGTGGTGAGCGGGCTGCAGGTGAGCCCGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCTCACCCCCTTTCAACCTCATACGACTGCCATTATAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ATTTCCCGGGCATGGAGCGTATGCAGGGCTGTTCGCCTG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCGCCCCGCACAAAGGGCTCAAGGATGAGGGAGAAGAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCTCCCGGGCTAACAGCGTACGGGGTGGGCCACCCCGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCCGGCTCGGCATACGCCGTTCCGAGGCTCTAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CAGGGAAGCGCAGACGAAGTTAGCCCAGACGAACCAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CACGGGTTAGGGCGCGGCCGCAAAACTCCCGGAGTAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CGCCCACCTGTGGCTTGGGGGTCCAGATGGACCAGAAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCGTGCGGGACCTGAGCGAGCTGGACGTCCCTTGGGA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CTTCCCCCTCCACGAGCCCCACCAAACGACAGGCCTCAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCCGATGGCCTCCTCCAGGGTGTAGGGGCCTTCCCGC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TGAGAGGGGGGTAGACCTCCTTCACCTCCTCGC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ACAACTGGAGGGCGGTGGTTATTACCGATGAAGAGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCGTGTATGGCGTCCCCAGCGTGGCGGTGGCAATCAGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GGGCGAGGCGCATCCTCGTCCCTGAGGGCGGGTTTTA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CGGGGCGTATGTGGCCGACAACCCCTCGGAGGAGGCCAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CAAAAAATCGGGGGGATCACGTTCCATTTTCTGTCCAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCGCCCGGGCCCACTCCTCCTCCGTCCGCCTGAGGAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCCACCGCGTGCGGGTAGCCCTGCGCTTGGAGACGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC

>NZ_AP017920|1|1|96922-99040|CRT
GTTTCGAACCCTCATAGGTACGGTCAAAAC	TAGGAGCCGCACGGCGTAAACCCCGGGTACGGCTTGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TGGGAGCGGCGGCGTAGGCGGGCAGTATGGCGGCGGACTT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCCGGGGCGGTGGTGTAGTTGGCCCTTTGAGGTCGCTTG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	AAACGCCCCGCTCAGCGCCCTGAGCGCCTGCTCGGCCT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CTTTAGTCAGCTCCGCACCACCCTGGACCCGCTTCT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	AGGAAAGAATTGCACGGTGGCTGAACGAGCGGAACGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TTCCCGGCGCAGGTCCTCGGAGGTACCGAGCGCGTCAAAC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCCCCGAGTTCCAGGCGTACGGCGGCAGGCAGAAAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GGTACATCTCTTGGGCTCAAAGGGTGGTAAAGCGCC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ATGGCCCTGCCGGAGCTTCGGCGGGCCATTAGGGAGGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TTTTCGAGGGGGGAGAAATGAAGTTGAGAGACTAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCGCAAGTACGTGGTGAGCGGGCTGCAGGTGAGCCCGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCTCACCCCCTTTCAACCTCATACGACTGCCATTATAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ATTTCCCGGGCATGGAGCGTATGCAGGGCTGTTCGCCTG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCGCCCCGCACAAAGGGCTCAAGGATGAGGGAGAAGAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCTCCCGGGCTAACAGCGTACGGGGTGGGCCACCCCGT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCCGGCTCGGCATACGCCGTTCCGAGGCTCTAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CAGGGAAGCGCAGACGAAGTTAGCCCAGACGAACCAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CACGGGTTAGGGCGCGGCCGCAAAACTCCCGGAGTAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CGCCCACCTGTGGCTTGGGGGTCCAGATGGACCAGAAA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCGTGCGGGACCTGAGCGAGCTGGACGTCCCTTGGGA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CTTCCCCCTCCACGAGCCCCACCAAACGACAGGCCTCAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CCCGATGGCCTCCTCCAGGGTGTAGGGGCCTTCCCGC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TGAGAGGGGGGTAGACCTCCTTCACCTCCTCGC
GTTTCAAACCCTCATAGGTACGGTCAAAAC	ACAACTGGAGGGCGGTGGTTATTACCGATGAAGAGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCGTGTATGGCGTCCCCAGCGTGGCGGTGGCAATCAGGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GGGCGAGGCGCATCCTCGTCCCTGAGGGCGGGTTTTA
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CGGGGCGTATGTGGCCGACAACCCCTCGGAGGAGGCCAT
GTTTCAAACCCTCATAGGTACGGTCAAAAC	CAAAAAATCGGGGGGATCACGTTCCATTTTCTGTCCAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	TCGCCCGGGCCCACTCCTCCTCCGTCCGCCTGAGGAG
GTTTCAAACCCTCATAGGTACGGTCAAAAC	GCCACCGCGTGCGGGTAGCCCTGCGCTTGGAGACGG
GTTTCAAACCCTCATAGGTACGGTCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017920.1\|WP_041444900.1\|93424_94525_+\|transposase	unknown	unknown	gnl\|CDD\|379252
NZ_AP017920.1\|WP_096410488.1\|94902_95808_-\|hypothetical-protein	cmr6gr7	mkCas0142_cmr6gr7_CAS-III-C	gnl\|CDD\|187857
NZ_AP017920.1\|WP_096412881.1\|104171_104900_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NZ_AP017920.1\|WP_096410498.1\|108445_108706_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_AP017920.1\|WP_096410490.1\|99247_100345_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_AP017920.1\|WP_096410482.1\|85597_86392_-\|carbohydrate-deacetylase	unknown	unknown	gnl\|CDD\|212113
NZ_AP017920.1\|WP_172844612.1\|87458_88370_-\|hypothetical-protein	cmr3gr5	mkCas0067_cmr3gr5_CAS-III-C	unknown
NZ_AP017920.1\|WP_096410496.1\|106768_107734_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|377458
NZ_AP017920.1\|WP_096410486.1\|90061_90718_-\|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|224255
NZ_AP017920.1\|WP_096410492.1\|101386_101908_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_AP017920.1\|WP_096410491.1\|100410_101394_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_AP017920.1\|WP_096410489.1\|95819_96809_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	csm3gr7	pfam03787_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187788
NZ_AP017920.1\|WP_096410499.1\|113139_113802_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_AP017920.1\|WP_096410485.1\|89199_90045_-\|transposase	unknown	unknown	unknown
NZ_AP017920.1\|WP_096410497.1\|107661_108264_+\|CRISPR-associated-protein-Cas5	cas5	mkCas0191_cas5_CAS-I-B	gnl\|CDD\|187823
NZ_AP017920.1\|WP_096410480.1\|75960_77058_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_AP017920.1\|WP_096410495.1\|104892_106788_+\|hypothetical-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|187861
NZ_AP017920.1\|WP_096410480.1\|111727_112825_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_AP017920.1\|WP_096410481.1\|84330_85584_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340890
NZ_AP017920.1\|WP_096410484.1\|88390_88762_-\|hypothetical-protein	cmr5gr11	mkCas0060_cmr5gr11_CAS-III-C	unknown

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_AP017920.1\|WP_096410496.1\|106768_107734_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	1.2e-62	206.5	0.0
NZ_AP017920.1\|WP_096410488.1\|94902_95808_-\|hypothetical-protein	cmr6gr7	mkCas0142_cmr6gr7_CAS-III-C	1.3e-72	239.1	0.0
NZ_AP017920.1\|WP_096412881.1\|104171_104900_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	1.3e-23	79.1	0.0
NZ_AP017920.1\|WP_096410492.1\|101386_101908_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	7.5e-42	137.9	0.0
NZ_AP017920.1\|WP_172844612.1\|87458_88370_-\|hypothetical-protein	cmr3gr5	mkCas0067_cmr3gr5_CAS-III-C	5.9e-59	194.5	0.0
NZ_AP017920.1\|WP_096410486.1\|90061_90718_-\|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.2e-28	94.2	0.0
NZ_AP017920.1\|WP_096410498.1\|108445_108706_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	1.2e-23	78.0	0.0
NZ_AP017920.1\|WP_096410489.1\|95819_96809_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	csm3gr7	pfam03787_csm3gr7_CAS-III-A:CAS-III-D	2e-18	62.1	0.1
NZ_AP017920.1\|WP_096410497.1\|107661_108264_+\|CRISPR-associated-protein-Cas5	cas5	mkCas0191_cas5_CAS-I-B	1e-28	95.0	0.0
NZ_AP017920.1\|WP_096410495.1\|104892_106788_+\|hypothetical-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	6.3e-41	135.4	0.0
NZ_AP017920.1\|WP_096410491.1\|100410_101394_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	7.4e-123	404.5	0.0
NZ_AP017920.1\|WP_096410484.1\|88390_88762_-\|hypothetical-protein	cmr5gr11	mkCas0060_cmr5gr11_CAS-III-C	1.1e-32	107.8	0.8

Protein	Function_ID	Function_description	E-value
NZ_AP017920.1\|WP_041444900.1\|93424_94525_+\|transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	0.000399149
NZ_AP017920.1\|WP_096410480.1\|111727_112825_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.11566e-09
NZ_AP017920.1\|WP_096410488.1\|94902_95808_-\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	1.69015e-16
NZ_AP017920.1\|WP_096412881.1\|104171_104900_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.28637e-25
NZ_AP017920.1\|WP_096410498.1\|108445_108706_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.15876e-27
NZ_AP017920.1\|WP_096410490.1\|99247_100345_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.14482e-08
NZ_AP017920.1\|WP_096410492.1\|101386_101908_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	8.67315e-60
NZ_AP017920.1\|WP_096410496.1\|106768_107734_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.46075e-63
NZ_AP017920.1\|WP_096410491.1\|100410_101394_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.05361e-155
NZ_AP017920.1\|WP_096410482.1\|85597_86392_-\|carbohydrate-deacetylase	gnl\|CDD\|212113	cd10802, YdjC_TTHB029_like, Thermus thermophiles TTHB029 and similar proteins. This subfamily is represented by an YdjC-family protein TTHB029 from Thermus thermophilus HB8; it is similar to Escherichia coli YdjC, a hypothetical protein encoded by the celG gene. TTHB029 functions as a homodimer. Each of monomer consists of (beta/alpha)-barrel fold. The molecular function of TTHB029 is unclear.	2.20112e-74
NZ_AP017920.1\|WP_096410489.1\|95819_96809_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.61231e-12
NZ_AP017920.1\|WP_096410499.1\|113139_113802_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.74774e-44
NZ_AP017920.1\|WP_096410497.1\|107661_108264_+\|CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.56164e-15
NZ_AP017920.1\|WP_096410480.1\|75960_77058_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.11566e-09
NZ_AP017920.1\|WP_096410495.1\|104892_106788_+\|hypothetical-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.1979e-49
NZ_AP017920.1\|WP_096410486.1\|90061_90718_-\|hypothetical-protein	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.59667e-22
NZ_AP017920.1\|WP_096410481.1\|84330_85584_-\|MFS-transporter	gnl\|CDD\|340890	cd17332, MFS_MelB_like, Salmonella enterica Na+/melibiose symporter MelB and similar transporters of the Major Facilitator Superfamily. This family is composed of Salmonella enterica Na+/melibiose symporter MelB, Major Facilitator Superfamily domain-containing proteins, MFSD2 and MFSD12, and other sugar transporters. MelB catalyzes the electrogenic symport of galactosides with Na+, Li+ or H+. The MFSD2 subfamily is composed of two vertebrate members, MFSD2A and MFSD2B. MFSD2A is more commonly called sodium-dependent lysophosphatidylcholine symporter 1 (NLS1). It is an LPC symporter that plays an essential role for blood-brain barrier formation and function. Inactivating mutations in MFSD2A cause a lethal microcephaly syndrome. MFSD2B is a potential risk or protect factor in the prognosis of lung adenocarcinoma. MelB-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.94656e-70

>NZ_AP017920.1|WP_096410489.1|95819_96809_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MEPKEWKLKALTDIWTGDRERKGDRLTPTGLMGSLRWWFEVLVRGLGGKACDPTAENVRCPGDNKKPHEGGHHCVVCELFGCTGWARKFRLMVLDDKGQVIQNQIRAGQTFVLRFIPLRPIAPEEWCLLDATLRLIADYGAIGGKTVFKPSDEPGRENVLHHKDFGLVTIEQRPEGVGCSRAIAEYVRDARWRKNFSDSAFSWASLQNFWCVKGRYLARQDTDTSSFNFVIGRPEPKNQSSQGDSWLAGRRPNRQLGIEPESKKVFSFKEPPRTFGFVQDEEEFSQIVEKLRILRDGDGNGRQPDPAWASFDPDREFLKGRQIIKQLFQ
>NZ_AP017920.1|WP_096410488.1|94902_95808_-|hypothetical-protein
MTWDYFVALSDNPGEQETLARPEGLSGGFVDEVSVRFFQGDKESARRRYMEGANGDIRLPEIISENAPDFSSLPSSTWVALQVDFELLTPWYSKDDRVFHLLDNPVCKDRVFGVPFMAASSWKGMLRWAFRMCTKKLVGPEQETDEGKLKQAKAWEWHLFGNEKGEGEEFSRGALVFYPTWFNKIGFEVINPHSRERRAGTQPIYYEVVPPGAQGTLSLLYAPWPGMKPAVKAEEVLPKLFEAVEALLTTYGISAKRTVGWGTAKILKWRAFHKTEGTVEKDNRADLEREVQAWLSAGGTP
>NZ_AP017920.1|WP_041444900.1|93424_94525_+|transposase
MRPVALSLLWTILALMPTPHLRESLKALLFLFLTGHGKARPQHSKTKSPSALSRFLNRYPWPTRALIRLAREEAQKALDRARRRKGPKPRLLVVLDLVTLEKRGHFPHLPLSFFHGKWGLHLVVLYLVYGDLRVPWAYRLWRGKGEKGLSLLALSLLASLPLWMRRTFRIRVAADAAFGTAWFLFGVRRLGLETVVGMRRDRRLRGGGRLLDLRRQGSRVYLWGLSFPVWVAWYRYPLPQGGWEWRYVVATFPATPRTMLTWGRRRFTVEHFFRAAKSEFSLGQFGQRTALGVHRFLVLSLLAYLLAHWVGVEGKGSWREAREGAARVLLPELVVQVILRELHALGLGPPGGGGEGLCGVCGRCKF
>NZ_AP017920.1|WP_096410486.1|90061_90718_-|hypothetical-protein
MTSYAKFVQIGLALDPIHVGAGGARIGRVDLTIVRDPATQVPKIPGSSLAGVYRTYVAMAEHERTPNRQVDGKEWPIYPNCAGLGQPKENQARTEEEKKYRRGHCGRPDCPVCTVFGFARGAGQEGGFAGLAAFTDAHVLLFPVPTRQGPMWVTGPMALRPIYPDIQGVDGNKVYLQKGSDNQLNLGWLLLPVEKRDMGEIKQKLHAFVCYLIWTPGV
>NZ_AP017920.1|WP_096410485.1|89199_90045_-|transposase
MRQDREHPLYHLDAETLLVAIYVWVDDELKALQAQGFKLPPKQKHQKATLAELLTLAIFVLLQGQDLAKGYLAAKTTLKAYFPSLPHLSRFYRVLQKAQGLLAHLAIRLSGGQGLLQVVDLKPIPLAHGHRIHGLDLPEAAVGVGPLGAFAGYVLMPVMNERGLFFRWAILPGNARETWGRDLLDGLPAVLGDRGFRWVQGVKTPPYRVRGGTVVETGWKEWMGRVRNWIETRFSVMVRSLGLHRIEARSYWGLVARVNLILLVHNLIRSRVLLRMAGVEL
>NZ_AP017920.1|WP_096410484.1|88390_88762_-|hypothetical-protein
MMNLDIRCAELGRQLASVRDQRGKPIEEKVLNAALAVLEEQGPYAMFLYLKARQEKVAGPMAEKSLAFLKDVFAKELQETRDILEAVKKLSEDLDKLLFARDLLRTALAYARYHVKARDEGAA
>NZ_AP017920.1|WP_172844612.1|87458_88370_-|hypothetical-protein
MWRLRSPLHLGTAPAGSLNRTRLYVPAYTLRGALINALAGKLGVGPSAYQKATQALDSRFRLTYLFPAEREGDKWFAWLPRYKEGQGLVWQREGREDSIPDRRFRMKLLSTRTSTAIDPGSDTASDGTLREVEVIHPWFAGEEPREVFLVGYVLYLPDSSKGSASPGGLEAQANREATPVEEEAKKYLLEEKGLEVFVGGELRYGLGRIELVHRSQEAKASLWDVQVDPNQNDPVVDRPGLLLAHGFAGGDQGEFKGSRECVAVWDNAPGRGGLKSRGLAWTPGTIPPELRWRIREDGFWEPA
>NZ_AP017920.1|WP_096410482.1|85597_86392_-|carbohydrate-deacetylase
MDLLERLGLGGRRVLILHHDDLGLSHAQNGAYQALGLPTGSVMVPGAWASGVKGEDLGVHLVLTSEWPAPRMRPLTEGESLRDEAGYFPESLEALWRKARAEEVERELCAQIEAARRLFSPTHLDTHQGAVLRPDLAEVYLRLAQAYRLVPLVPESLEGLGVPPLFLSELERLLYTAPFPRVRFLDPYGLPPEERLGFYLGLAHLPPGLYYLVHHSALPTPEGRALPDWPTREADYFALSHPEVRRVLAEFHPLTWRAVREVLF
>NZ_AP017920.1|WP_096410481.1|84330_85584_-|MFS-transporter
MRKWRYASGQLGLTLVSESFGTYLAFFYLERLGLSAALYALARTAYALWDAVNDPLFGHLSDRTKTPWGRRRPWLLLGVPLFLLAYLLVFWVPDWARSPAVLPYYFALAILLYETMATVVWTNHGALFPEMFRGLKERAEAAALKRGAELLGLILGIALAPMVYARVGFFGMALLFAGLALLAFLYFFPGIREDPRAGSGLELWASFRLVLANRAFWVVALVGLLFEFGRMVLQTAIPFYAKHALGLEEGATTFLFAAVFLAALPSALLWGRLAGVWGGKRAWRLAHLLMGLATLLLFLPQSLPAALLAGALVGAGFAGVRVTGEVVMAKVIDLDAERTETRREGAYYSLVGLLGRAAGALVGLSFALLTPLFGYVSGENPGPNPEAAFRFLGAVVPGTAILLAYALTALFPHEVKE
>NZ_AP017920.1|WP_096410480.1|75960_77058_+|IS4-family-transposase
MPPTTPLSQVITLWVHKVFASLRKTIRSNLALFLSTLLTTPLDPTLSDLARRTPLPTLAQSRLNRLWRFLHHPTLQDPWALTEALLPLLVPRFPKDRPLPLIVDWTFTEDGRHQALVAALPLKGRALVVAFALHPLSPFPSQNRVEEEFLHRLGRAVQDLGYTPLFLLDRGFDRVSLMRKLQGWGMGFLIRLRQNREVEPQGGKRLPLKEGYRRVVHPLREEVRLFGHGGEGVEVTLLVYPGGRDPWYLAYSGPFGGEPPYGWRMWIEEGFRDLKGQGFGLDRHRLRTGASLRGWLWLLALGMALLVLLGARLQGREWLPRLLAHPERQSLFRLGRIALAQGPPPWREAVVEELVRLLQELGGGK
>NZ_AP017920.1|WP_096410490.1|99247_100345_+|IS4-family-transposase
MPPTTPLSQVITLWVHKVFASLRKTIRSNLALFLSTLLTTPLDPTLSDLARRTPLPTLAQSRLNRLWRFLHHPTLQDPWALTEALLPLLVPRFPKDRPLPLIVDWTFTEDGRHQALVAALPLKGRALVVAFALHPLSPFPSQNRVEEEFLHRLGRAVQDLGYTPLFLLDRGFDRVSLMRKLQGWGMGFLIRLRQNREVEPQGGKRLPLKEGYQRVVHPLREEVRLFGHGGEGVEVTLLVYPGGRDPWYLAYSGPFGGEPPYGWRMWIEEGFRDLKGQGFGLDRHRLRTGASLRGWLWLLALGMALLVLLGARLQGREWLPRLLAHPERQSLFRLGRIALAQGPPPWREAVVEELVRLLQELGGGK
>NZ_AP017920.1|WP_096410491.1|100410_101394_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MAKPVYVFSSGRLGRRANTIVLETEERKRHLPVEQVSELYLFGEVDLNKRFLEFVAQKGILLHFFNRFGYYVGSFYPREHLLSGYLTLRQAEHYLDGGKRLDLARRFVEGGLGNVLRLLRREEARGEGLEATLELLEELLAKVGEAQSVGELMALEGRAREAYYRTWEALLGEAWALERSRRPPRDPINALLSFANSLLYTAILAQIYQTHLDPRIGFLHEANYRRHSLNLDVAEVFRPVLADRLVFRLVRRGQVKPGHFLREGEGVFLSEAGRRLVVEEWEKTLQTTYQHRALRRAVSYRTTLRLELYKLEKHLIGEQPYTPYRLR
>NZ_AP017920.1|WP_096410492.1|101386_101908_-|CRISPR-associated-protein-Cas4
MGDGPVPITATLVGYYGVCPREAWLMGHALSPFPDHELLALGRLLQETAYREARKEVALPGMRLDLLTKGKDAWVVAEVKRRSGQREAHLLQLGYYLLRLEALGLRAQGELRYPEERRAERVALTPELRARVQEAERALKELLQRPLPPPPKRIPACSGCAYFEFCFVEEKDG
>NZ_AP017920.1|WP_096412881.1|104171_104900_+|CRISPR-associated-endoribonuclease-Cas6
MASLSGGRIRLRLYAEGRLPVTYREGLQAALYGVLPSPLGQRLHDEGLLGGRRPLKLFVFSRLLGLTYLKEEKAFLAQGELTLYFASALAEVVGALGQGVWRRGGLEVHGLFLRLVEMGLEPLPVGERLVVEALAPIAAYRTEGGKTLYFNPLNREFPLLLEANLNRKAEALGLPRGSLEVVPLGFHPRQKRLERYKGTWVEGWMGRYRLAGPPHLLRLALLSGLGAKNSQGFGFVREVEGA
>NZ_AP017920.1|WP_096410495.1|104892_106788_+|hypothetical-protein
MLRELIRMGREVAGEGDVLEDLVQEASGTLYLLDLHPEARRASLVPYELDGEKCRRFLWVGDPPAANAPRDRATTSRLHYLLGQVATKMAEDEGLYPLLKDLLWDPGKPGGKVRHLLDLRDFRLEEAREAEEGPFRVVGGRLQVAQDPWPLLEEKKRHAGGLAEALGAFLERVWGLPRKGALFSLALRGRPLAEAPEYRAYLRRILLEERFARAEKGLCHGCGRVDRVVADSSAFRLKFFIQDKKGFAPGVRGEAFPRAYALCRECFTALKVGERLALERLTLRFLGTEALVLPGADPEPGGLARLVERVLAQVRGLERLEAWREFLERARLRWEGVGYLGFSLLFFRRAQAATKVEEVVLEVPPSRVEGLFRALEEAQGRGFPVRGLGDWLRLLPLSRGRGGVDAGPALPWLSRILLGLPLDPKALLPLWLRAAERAYREDATFYALQGFRGPQGALDLALLGAGWIWVLRRLGLWGGSMEREVRSAFPLGEEEEVFRAYGFGPLEAGLYLLGKAMEAVGQAQARLYEYRKEPLLEALGWQGMSLVRVRHLVPEVMARAVHYLDGEGRTQVLDLLGRATDLLERAEGGLSEREVPYYILMGYAQARSRRLRQGRKAEQDQEGVEHDREGA
>NZ_AP017920.1|WP_096410496.1|106768_107734_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MTEKVPNAEILFLYEAKDTNPNGDPDAENRPRMDYVGRRLLVSDVRLKRYVRDYLLLRGEDVWVRTREDGSRTDADGRLQELMNLYAKETGREAGAKKDLDPDFLKWYLRRLRDVRLFGAVLPIKGEGEAKGGTGQFVGPVQFDWGYSLHPVEVYTATLSSHFAGRTEGGKGEHGTFGKDHRVPYALIAFWGRVSRARAEKVGLSPEDLEVLEKGLLEGLLQGATTRSKVGQTPRLYLRVDWVEGFRPLGDPRDGLALRPAEGKAPEAIRSVADYTLDARALARGLARYREAVARVRLWVHPDLRVEGLSLEGFPLEEVRF
>NZ_AP017920.1|WP_096410497.1|107661_108264_+|CRISPR-associated-protein-Cas5
MGPPGPAGGGAFPGGVPVGGGALLRALRFVLKGKRAHFRRFYTNSSALTYPVPPPSALQGLLGAALGLGPEYPKALSGLYLSVRPLGAQRHLFQTVNYLFIKEARLEELRGLSGEGRTQIPSSSWWGRGGGPWPLRSGWPRRTPTSCSAWRGPSRPPPTPSPWGAPSPSPGPRRWGFSRGRWCGAGRARGWAGGRRPGSA
>NZ_AP017920.1|WP_096410498.1|108445_108706_+|CRISPR-associated-endonuclease-Cas2
MYVVMVYDVAVERVAKVLQVGRRYLTWVQNSVLEGELSPAQFARLKAEVRKVIEPTDAVRFYVLPGPGALRIEVLGTSKNEPGQIV
>NZ_AP017920.1|WP_096410480.1|111727_112825_+|IS4-family-transposase
MPPTTPLSQVITLWVHKVFASLRKTIRSNLALFLSTLLTTPLDPTLSDLARRTPLPTLAQSRLNRLWRFLHHPTLQDPWALTEALLPLLVPRFPKDRPLPLIVDWTFTEDGRHQALVAALPLKGRALVVAFALHPLSPFPSQNRVEEEFLHRLGRAVQDLGYTPLFLLDRGFDRVSLMRKLQGWGMGFLIRLRQNREVEPQGGKRLPLKEGYRRVVHPLREEVRLFGHGGEGVEVTLLVYPGGRDPWYLAYSGPFGGEPPYGWRMWIEEGFRDLKGQGFGLDRHRLRTGASLRGWLWLLALGMALLVLLGARLQGREWLPRLLAHPERQSLFRLGRIALAQGPPPWREAVVEELVRLLQELGGGK
>NZ_AP017920.1|WP_096410499.1|113139_113802_+|GntR-family-transcriptional-regulator
MAVVPEGKVTEGQSAYQRLRSAILEGELLPGQRLVEKDLAERFGLGRAAIRTALARLEQEGLVESAPYRGAWVRILSEEEALEVLEARMALESLAARHAARKATPEDIARLQGILREMEEHYARGDLLAMSELNALFHRTLVEASRHRTAARLIEALRAQGVRHQYRTILVPGRSQRSLEEHRRILEAVSARDEEAAERAMREHLQGVMAALRQAKGGPA

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Crispr_ID: NZ_AP017920_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017920_2

108887-110123

TypeIII

Consensus_repeat	Method
GTTTCAAACCCTCATAGGTACGGTCAAAAC	PILER-CR
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CRISPRCasFinder
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CRT

18 spacers

cas2,cas5,cas7,cas8b1,cas6,cas4,cas1,csm3gr7,cmr6gr7

The CRISPR arrays of NZ_AP017920_2

>merge|NZ_AP017920|2|108887-110123|PILER-CR,CRISPRCasFinder,CRT
GTTTTGACCGTACCTATGAGGGTTTGAAACTGATGCGGCGTTTCGCGGTGCTTCTCCTCGGTTCCCTAGTTTTGACCGTACCTATGAGGGTTTGAAACATAACTGCCATGCGGATTGACCTGGAACGAACTCGCTCGTTTTGACCGTACCTATGAGGGTTTGAAACCTACGTGGGTACTGGGGGGGGCATCCTCTAGCGAGGCCCGGTTTTGACCGTACCTATGAGGGTTTGAAACACGCCTATCTCACCGAGGATCCTTTCGTGGTCGCCAAGTTTTGACCGTACCTATGAGGGTTTGAAACGATCTACGACCCCCACTGGGCCTGGGCGTGGCCCCGGGTTTTGACCGTACCTATGAGGGTTTGAAACCCTGCGCTTCGCCACCGGAGACCGCCTGCGGCTGGACGGGTTTTGACCGTACCTATGAGGGTTTGAAACCGTTTGCCGTGCCTGTGTTGTATTGACCTACCTCTAGGTTTTGACCGTACCTATGAGGGTTTGAAACCTCGTAGAGGAGCGTGATGGTCCGGAGCTTTTCCACGGTTTTGACCGTACCTATGAGGGTTTGAAACAGGACAACCAGCGAGCGCTCCTCCACCTGACCAGGGGTTTTGACCGTACCTATGAGGGTTTGAAACTCAGTGTGCCCGGGGTGGACCCCGCGAATGGGATCGTTTTGACCGTACCTATGAGGGTTTGAAACCTTGCCCGTGTGGTTTCCCGAAGACACAGGGGCCCTGGTTTTGACCGTACCTATGAGGGTTTGAAACTACTCACCGAACTCTCTGGGCCCTGGCCGGATCACTCAGGTTTTGACCGTACCTATGAGGGTTTGAAACCCTGGCCCCTTTCACCCGTCAATATGACGGGACCAGTTGTTTTGACCGTACCTATGAGGGTTTGAAACAGGTGGTCCACGAGCCCCCGGTCCACCAACACGGGAAGTTTTGACCGTACCTATGAGAGCTCCCCGACCTCGCCCTCATGCGAGGGGAAGACACGGGTTTTGACCGTACCTATGAGGGTTTGAAACCCGAGCTTTTCCAGGGTCATGCCTCACCTCCGAGGAGTTTTGACCGTACCTATGAGGGTTTGAAACCCCCGATGGACGCCCCCACCTGCACCGGGTCCCCCACGTTTTGACCGTACCTATGAGGGTTTGAAACGCGATCTCCCGGGCCACGCGCTGGAGCATGTCCTCTACCCGTTTTGACCGTACCTAGGGCTTGCCTTGCA

>NZ_AP017920|2|2|108887-110053|PILER-CR
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TGATGCGGCGTTTCGCGGTGCTTCTCCTCGGTTCCCTA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	ATAACTGCCATGCGGATTGACCTGGAACGAACTCGCTC
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTACGTGGGTACTGGGGGGGGCATCCTCTAGCGAGGCCCG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	ACGCCTATCTCACCGAGGATCCTTTCGTGGTCGCCAA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	GATCTACGACCCCCACTGGGCCTGGGCGTGGCCCCGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGCGCTTCGCCACCGGAGACCGCCTGCGGCTGGACGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CGTTTGCCGTGCCTGTGTTGTATTGACCTACCTCTAG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTCGTAGAGGAGCGTGATGGTCCGGAGCTTTTCCACG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGACAACCAGCGAGCGCTCCTCCACCTGACCAGGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TCAGTGTGCCCGGGGTGGACCCCGCGAATGGGATC
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTTGCCCGTGTGGTTTCCCGAAGACACAGGGGCCCTG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TACTCACCGAACTCTCTGGGCCCTGGCCGGATCACTCAG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGGCCCCTTTCACCCGTCAATATGACGGGACCAGTT
GTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGTGGTCCACGAGCCCCCGGTCCACCAACACGGGAA
GTTTTGACCGTACCTATGAGAGCTCCCCGA	CCTCGCCCTCATGCGAGGGGAAGACACGGGTTTTGACCG
TACCTATGAGGGTTTGAAACCCGAGCTTTT	CCAGGGTCATGCCTCACCTCCGAGGAGTTTTGACCG
TACCTATGAGGGTTTGAAACCCCCGATGGA	CGCCCCCACCTGCACCGGGTCCCCCACGTTTTGACCG
TACCTATGAGGGTTTGAAAC

>NZ_AP017920|2|2|108887-110053|CRISPRCasFinder
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TGATGCGGCGTTTCGCGGTGCTTCTCCTCGGTTCCCTA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	ATAACTGCCATGCGGATTGACCTGGAACGAACTCGCTC
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTACGTGGGTACTGGGGGGGGCATCCTCTAGCGAGGCCCG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	ACGCCTATCTCACCGAGGATCCTTTCGTGGTCGCCAA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	GATCTACGACCCCCACTGGGCCTGGGCGTGGCCCCGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGCGCTTCGCCACCGGAGACCGCCTGCGGCTGGACGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CGTTTGCCGTGCCTGTGTTGTATTGACCTACCTCTAG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTCGTAGAGGAGCGTGATGGTCCGGAGCTTTTCCACG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGACAACCAGCGAGCGCTCCTCCACCTGACCAGGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TCAGTGTGCCCGGGGTGGACCCCGCGAATGGGATC
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTTGCCCGTGTGGTTTCCCGAAGACACAGGGGCCCTG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TACTCACCGAACTCTCTGGGCCCTGGCCGGATCACTCAG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGGCCCCTTTCACCCGTCAATATGACGGGACCAGTT
GTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGTGGTCCACGAGCCCCCGGTCCACCAACACGGGAA
GTTTTGACCGTACCTATGAGAGCTCCCCGA	CCTCGCCCTCATGCGAGGGGAAGACACGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCGAGCTTTTCCAGGGTCATGCCTCACCTCCGAGGA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCCCGATGGACGCCCCCACCTGCACCGGGTCCCCCAC
GTTTTGACCGTACCTATGAGGGTTTGAAAC

>NZ_AP017920|2|2|108887-110123|CRT
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TGATGCGGCGTTTCGCGGTGCTTCTCCTCGGTTCCCTA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	ATAACTGCCATGCGGATTGACCTGGAACGAACTCGCTC
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTACGTGGGTACTGGGGGGGGCATCCTCTAGCGAGGCCCG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	ACGCCTATCTCACCGAGGATCCTTTCGTGGTCGCCAA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	GATCTACGACCCCCACTGGGCCTGGGCGTGGCCCCGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGCGCTTCGCCACCGGAGACCGCCTGCGGCTGGACGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CGTTTGCCGTGCCTGTGTTGTATTGACCTACCTCTAG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTCGTAGAGGAGCGTGATGGTCCGGAGCTTTTCCACG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGACAACCAGCGAGCGCTCCTCCACCTGACCAGGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TCAGTGTGCCCGGGGTGGACCCCGCGAATGGGATC
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CTTGCCCGTGTGGTTTCCCGAAGACACAGGGGCCCTG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	TACTCACCGAACTCTCTGGGCCCTGGCCGGATCACTCAG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGGCCCCTTTCACCCGTCAATATGACGGGACCAGTT
GTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGTGGTCCACGAGCCCCCGGTCCACCAACACGGGAA
GTTTTGACCGTACCTATGAGAGCTCCCCGA	CCTCGCCCTCATGCGAGGGGAAGACACGG
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCGAGCTTTTCCAGGGTCATGCCTCACCTCCGAGGA
GTTTTGACCGTACCTATGAGGGTTTGAAAC	CCCCGATGGACGCCCCCACCTGCACCGGGTCCCCCAC
GTTTTGACCGTACCTATGAGGGTTTGAAAC	GCGATCTCCCGGGCCACGCGCTGGAGCATGTCCTCTACCC
GTTTTGACCGTACCTAGGGCTTGCCTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017920.1\|WP_096410496.1\|106768_107734_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|377458
NZ_AP017920.1\|WP_096410488.1\|94902_95808_-\|hypothetical-protein	cmr6gr7	mkCas0142_cmr6gr7_CAS-III-C	gnl\|CDD\|187857
NZ_AP017920.1\|WP_096412881.1\|104171_104900_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NZ_AP017920.1\|WP_096410507.1\|123134_124058_+\|acetaldehyde-dehydrogenase-(acetylating)	unknown	unknown	gnl\|CDD\|236227
NZ_AP017920.1\|WP_096410490.1\|99247_100345_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_AP017920.1\|WP_096410492.1\|101386_101908_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_AP017920.1\|WP_096410505.1\|119345_120320_-\|catechol-2,3-dioxygenase	unknown	unknown	gnl\|CDD\|274480
NZ_AP017920.1\|WP_096410504.1\|118752_119241_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380560
NZ_AP017920.1\|WP_096410500.1\|113794_114709_+\|cytosolic-protein	unknown	unknown	gnl\|CDD\|188342
NZ_AP017920.1\|WP_096410502.1\|115428_116097_+\|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	unknown	unknown	gnl\|CDD\|181735
NZ_AP017920.1\|WP_096410498.1\|108445_108706_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_AP017920.1\|WP_096410489.1\|95819_96809_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	csm3gr7	pfam03787_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187788
NZ_AP017920.1\|WP_096410506.1\|120520_122086_-\|Pyoverdin-chromophore-biosynthetic-protein-pvcC	unknown	unknown	gnl\|CDD\|213700
NZ_AP017920.1\|WP_096410499.1\|113139_113802_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_AP017920.1\|WP_096410497.1\|107661_108264_+\|CRISPR-associated-protein-Cas5	cas5	mkCas0191_cas5_CAS-I-B	gnl\|CDD\|187823
NZ_AP017920.1\|WP_096410503.1\|117624_118845_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_AP017920.1\|WP_096410495.1\|104892_106788_+\|hypothetical-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|187861
NZ_AP017920.1\|WP_096410480.1\|111727_112825_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_AP017920.1\|WP_096410491.1\|100410_101394_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_AP017920.1\|WP_096410501.1\|114705_115416_+\|PIG-L-family-deacetylase	unknown	unknown	gnl\|CDD\|225031

Protein	Function_ID	Function_description	E-value
NZ_AP017920.1\|WP_096410496.1\|106768_107734_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.46075e-63
NZ_AP017920.1\|WP_096410488.1\|94902_95808_-\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	1.69015e-16
NZ_AP017920.1\|WP_096412881.1\|104171_104900_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.28637e-25
NZ_AP017920.1\|WP_096410507.1\|123134_124058_+\|acetaldehyde-dehydrogenase-(acetylating)	gnl\|CDD\|236227	PRK08300, PRK08300, acetaldehyde dehydrogenase; Validated.	0
NZ_AP017920.1\|WP_096410490.1\|99247_100345_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.14482e-08
NZ_AP017920.1\|WP_096410492.1\|101386_101908_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	8.67315e-60
NZ_AP017920.1\|WP_096410505.1\|119345_120320_-\|catechol-2,3-dioxygenase	gnl\|CDD\|274480	TIGR03211, catechol_2_3, catechol 2,3 dioxygenase. Members of this family all are enzymes active as catechol 2,3 dioxygenase (1.13.11.2), although some members have highly significant activity on catechol derivatives such as 3-methylcatechol, 3-chlorocatechol, and 4-chlorocatechol (see Mars, et al.). This enzyme is also called metapyrocatechase, as it performs a meta-cleavage (an extradiol ring cleavage), in contrast to the ortho-cleavage (intradiol ring cleavage)performed by catechol 1,2-dioxygenase (EC 1.13.11.1), also called pyrocatechase. [Energy metabolism, Other].	2.89513e-153
NZ_AP017920.1\|WP_096410504.1\|118752_119241_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380560	cd06337, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.	6.16562e-54
NZ_AP017920.1\|WP_096410500.1\|113794_114709_+\|cytosolic-protein	gnl\|CDD\|188342	TIGR03581, EF_0839, conserved hypothetical protein EF_0839/AHA_3917. Members of this family of relatively uncommon proteins are found in both Gram-positive (e.g. Enterococcus faecalis) and Gram-negative (e.g. Aeromonas hydrophila) bacteria, as part of a cluster of conserved proteins. The function is unknown. [Hypothetical proteins, Conserved].	0.00770893
NZ_AP017920.1\|WP_096410502.1\|115428_116097_+\|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	gnl\|CDD\|181735	PRK09262, PRK09262, hypothetical protein; Provisional.	9.69412e-54
NZ_AP017920.1\|WP_096410498.1\|108445_108706_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.15876e-27
NZ_AP017920.1\|WP_096410489.1\|95819_96809_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.61231e-12
NZ_AP017920.1\|WP_096410506.1\|120520_122086_-\|Pyoverdin-chromophore-biosynthetic-protein-pvcC	gnl\|CDD\|213700	TIGR02310, HpaB-2, 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component. This gene for this monooxygenase is found within apparent operons for the degradation of 4-hydroxyphenylacetic acid in Shigella, Photorhabdus and Pasteurella. The family represented by this model is narrowly limited to gammaproteobacteria to exclude other aromatic hydroxylases involved in various secondary metabolic pathways. Generally, this enzyme acts with the assistance of a small flavin reductase domain protein (HpaC) to provide the cycle the flavin reductant for the reaction. This family of sequences is a member of a larger subfamily of monooxygenases (pfam03241).	0
NZ_AP017920.1\|WP_096410499.1\|113139_113802_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.74774e-44
NZ_AP017920.1\|WP_096410497.1\|107661_108264_+\|CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.56164e-15
NZ_AP017920.1\|WP_096410503.1\|117624_118845_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	1.59989e-89
NZ_AP017920.1\|WP_096410495.1\|104892_106788_+\|hypothetical-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.1979e-49
NZ_AP017920.1\|WP_096410480.1\|111727_112825_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.11566e-09
NZ_AP017920.1\|WP_096410491.1\|100410_101394_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.05361e-155
NZ_AP017920.1\|WP_096410501.1\|114705_115416_+\|PIG-L-family-deacetylase	gnl\|CDD\|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	1.18052e-32

>NZ_AP017920.1|WP_096410498.1|108445_108706_+|CRISPR-associated-endonuclease-Cas2
MYVVMVYDVAVERVAKVLQVGRRYLTWVQNSVLEGELSPAQFARLKAEVRKVIEPTDAVRFYVLPGPGALRIEVLGTSKNEPGQIV
>NZ_AP017920.1|WP_096410497.1|107661_108264_+|CRISPR-associated-protein-Cas5
MGPPGPAGGGAFPGGVPVGGGALLRALRFVLKGKRAHFRRFYTNSSALTYPVPPPSALQGLLGAALGLGPEYPKALSGLYLSVRPLGAQRHLFQTVNYLFIKEARLEELRGLSGEGRTQIPSSSWWGRGGGPWPLRSGWPRRTPTSCSAWRGPSRPPPTPSPWGAPSPSPGPRRWGFSRGRWCGAGRARGWAGGRRPGSA
>NZ_AP017920.1|WP_096410496.1|106768_107734_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MTEKVPNAEILFLYEAKDTNPNGDPDAENRPRMDYVGRRLLVSDVRLKRYVRDYLLLRGEDVWVRTREDGSRTDADGRLQELMNLYAKETGREAGAKKDLDPDFLKWYLRRLRDVRLFGAVLPIKGEGEAKGGTGQFVGPVQFDWGYSLHPVEVYTATLSSHFAGRTEGGKGEHGTFGKDHRVPYALIAFWGRVSRARAEKVGLSPEDLEVLEKGLLEGLLQGATTRSKVGQTPRLYLRVDWVEGFRPLGDPRDGLALRPAEGKAPEAIRSVADYTLDARALARGLARYREAVARVRLWVHPDLRVEGLSLEGFPLEEVRF
>NZ_AP017920.1|WP_096410495.1|104892_106788_+|hypothetical-protein
MLRELIRMGREVAGEGDVLEDLVQEASGTLYLLDLHPEARRASLVPYELDGEKCRRFLWVGDPPAANAPRDRATTSRLHYLLGQVATKMAEDEGLYPLLKDLLWDPGKPGGKVRHLLDLRDFRLEEAREAEEGPFRVVGGRLQVAQDPWPLLEEKKRHAGGLAEALGAFLERVWGLPRKGALFSLALRGRPLAEAPEYRAYLRRILLEERFARAEKGLCHGCGRVDRVVADSSAFRLKFFIQDKKGFAPGVRGEAFPRAYALCRECFTALKVGERLALERLTLRFLGTEALVLPGADPEPGGLARLVERVLAQVRGLERLEAWREFLERARLRWEGVGYLGFSLLFFRRAQAATKVEEVVLEVPPSRVEGLFRALEEAQGRGFPVRGLGDWLRLLPLSRGRGGVDAGPALPWLSRILLGLPLDPKALLPLWLRAAERAYREDATFYALQGFRGPQGALDLALLGAGWIWVLRRLGLWGGSMEREVRSAFPLGEEEEVFRAYGFGPLEAGLYLLGKAMEAVGQAQARLYEYRKEPLLEALGWQGMSLVRVRHLVPEVMARAVHYLDGEGRTQVLDLLGRATDLLERAEGGLSEREVPYYILMGYAQARSRRLRQGRKAEQDQEGVEHDREGA
>NZ_AP017920.1|WP_096412881.1|104171_104900_+|CRISPR-associated-endoribonuclease-Cas6
MASLSGGRIRLRLYAEGRLPVTYREGLQAALYGVLPSPLGQRLHDEGLLGGRRPLKLFVFSRLLGLTYLKEEKAFLAQGELTLYFASALAEVVGALGQGVWRRGGLEVHGLFLRLVEMGLEPLPVGERLVVEALAPIAAYRTEGGKTLYFNPLNREFPLLLEANLNRKAEALGLPRGSLEVVPLGFHPRQKRLERYKGTWVEGWMGRYRLAGPPHLLRLALLSGLGAKNSQGFGFVREVEGA
>NZ_AP017920.1|WP_096410492.1|101386_101908_-|CRISPR-associated-protein-Cas4
MGDGPVPITATLVGYYGVCPREAWLMGHALSPFPDHELLALGRLLQETAYREARKEVALPGMRLDLLTKGKDAWVVAEVKRRSGQREAHLLQLGYYLLRLEALGLRAQGELRYPEERRAERVALTPELRARVQEAERALKELLQRPLPPPPKRIPACSGCAYFEFCFVEEKDG
>NZ_AP017920.1|WP_096410491.1|100410_101394_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MAKPVYVFSSGRLGRRANTIVLETEERKRHLPVEQVSELYLFGEVDLNKRFLEFVAQKGILLHFFNRFGYYVGSFYPREHLLSGYLTLRQAEHYLDGGKRLDLARRFVEGGLGNVLRLLRREEARGEGLEATLELLEELLAKVGEAQSVGELMALEGRAREAYYRTWEALLGEAWALERSRRPPRDPINALLSFANSLLYTAILAQIYQTHLDPRIGFLHEANYRRHSLNLDVAEVFRPVLADRLVFRLVRRGQVKPGHFLREGEGVFLSEAGRRLVVEEWEKTLQTTYQHRALRRAVSYRTTLRLELYKLEKHLIGEQPYTPYRLR
>NZ_AP017920.1|WP_096410490.1|99247_100345_+|IS4-family-transposase
MPPTTPLSQVITLWVHKVFASLRKTIRSNLALFLSTLLTTPLDPTLSDLARRTPLPTLAQSRLNRLWRFLHHPTLQDPWALTEALLPLLVPRFPKDRPLPLIVDWTFTEDGRHQALVAALPLKGRALVVAFALHPLSPFPSQNRVEEEFLHRLGRAVQDLGYTPLFLLDRGFDRVSLMRKLQGWGMGFLIRLRQNREVEPQGGKRLPLKEGYQRVVHPLREEVRLFGHGGEGVEVTLLVYPGGRDPWYLAYSGPFGGEPPYGWRMWIEEGFRDLKGQGFGLDRHRLRTGASLRGWLWLLALGMALLVLLGARLQGREWLPRLLAHPERQSLFRLGRIALAQGPPPWREAVVEELVRLLQELGGGK
>NZ_AP017920.1|WP_096410489.1|95819_96809_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MEPKEWKLKALTDIWTGDRERKGDRLTPTGLMGSLRWWFEVLVRGLGGKACDPTAENVRCPGDNKKPHEGGHHCVVCELFGCTGWARKFRLMVLDDKGQVIQNQIRAGQTFVLRFIPLRPIAPEEWCLLDATLRLIADYGAIGGKTVFKPSDEPGRENVLHHKDFGLVTIEQRPEGVGCSRAIAEYVRDARWRKNFSDSAFSWASLQNFWCVKGRYLARQDTDTSSFNFVIGRPEPKNQSSQGDSWLAGRRPNRQLGIEPESKKVFSFKEPPRTFGFVQDEEEFSQIVEKLRILRDGDGNGRQPDPAWASFDPDREFLKGRQIIKQLFQ
>NZ_AP017920.1|WP_096410488.1|94902_95808_-|hypothetical-protein
MTWDYFVALSDNPGEQETLARPEGLSGGFVDEVSVRFFQGDKESARRRYMEGANGDIRLPEIISENAPDFSSLPSSTWVALQVDFELLTPWYSKDDRVFHLLDNPVCKDRVFGVPFMAASSWKGMLRWAFRMCTKKLVGPEQETDEGKLKQAKAWEWHLFGNEKGEGEEFSRGALVFYPTWFNKIGFEVINPHSRERRAGTQPIYYEVVPPGAQGTLSLLYAPWPGMKPAVKAEEVLPKLFEAVEALLTTYGISAKRTVGWGTAKILKWRAFHKTEGTVEKDNRADLEREVQAWLSAGGTP
>NZ_AP017920.1|WP_096410480.1|111727_112825_+|IS4-family-transposase
MPPTTPLSQVITLWVHKVFASLRKTIRSNLALFLSTLLTTPLDPTLSDLARRTPLPTLAQSRLNRLWRFLHHPTLQDPWALTEALLPLLVPRFPKDRPLPLIVDWTFTEDGRHQALVAALPLKGRALVVAFALHPLSPFPSQNRVEEEFLHRLGRAVQDLGYTPLFLLDRGFDRVSLMRKLQGWGMGFLIRLRQNREVEPQGGKRLPLKEGYRRVVHPLREEVRLFGHGGEGVEVTLLVYPGGRDPWYLAYSGPFGGEPPYGWRMWIEEGFRDLKGQGFGLDRHRLRTGASLRGWLWLLALGMALLVLLGARLQGREWLPRLLAHPERQSLFRLGRIALAQGPPPWREAVVEELVRLLQELGGGK
>NZ_AP017920.1|WP_096410499.1|113139_113802_+|GntR-family-transcriptional-regulator
MAVVPEGKVTEGQSAYQRLRSAILEGELLPGQRLVEKDLAERFGLGRAAIRTALARLEQEGLVESAPYRGAWVRILSEEEALEVLEARMALESLAARHAARKATPEDIARLQGILREMEEHYARGDLLAMSELNALFHRTLVEASRHRTAARLIEALRAQGVRHQYRTILVPGRSQRSLEEHRRILEAVSARDEEAAERAMREHLQGVMAALRQAKGGPA
>NZ_AP017920.1|WP_096410500.1|113794_114709_+|cytosolic-protein
MRELPGTRPRPPSGGWDLHVHVEPDLLPRKTDDLTLARRFREMGLKGFLLKSHYAPTAERAQVVRKAVPGVEVLGAVVLNHGVGGLNPLAVEVAARAGARFVWFPTVDAANEARHLEKLPPEKRPQWAGLMEALRKEGTVPEPIALLDASGRLRPEARAVLKVAARHGMVVATGHLSREEVFRVVEAALEEGVSQVVVTHPDYPTQALSLEDQRLLARWGAYLERCFAPSHTGKVPWEALFRAIRATPLERNFVSTDLGQPQNPPVEEGLVLMAERLLEAGFDEAEVRHMAVTVPEKLALGGER
>NZ_AP017920.1|WP_096410501.1|114705_115416_+|PIG-L-family-deacetylase
MKRLLVVSAHAADFVWRAGGAIALAVAQGGEALVVALSYGERGESGELWKEPGQTLERVKAIREAEARRAAEVLGAGFVGLDLGDYPLRVGEEALWRLVDILVNFAPDVLITHTPKDPFNPDHPVAYEATEKARQLASGAGVASAFRTIRPPEFWLFEPHQPELCGFVPNLFLDITPAWEKKRAAMEVFASQAYLVRYYSERAEHRANHARRISGFKDIERAEAFQRVLPQVLRAL
>NZ_AP017920.1|WP_096410502.1|115428_116097_+|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase
MLSQEEIQELAALGTATVYEASGRKGLVEAGFVRLPEGSRAAGPAFPVLCAQGDNLGVHAAMAAVRPGEVLVLAMPEPEPVALVGELLATQAKARGVAALLVDGAVRDADGLRLLGLPIWARFVSPRGARRERVLGLGTPVWVGGVEVRLGDYVVLDGDGVVVLPRERAREVLQRARERAEREAALRARFARGELSVDVYGLRQNLREALAEAERLRGGEDG
>NZ_AP017920.1|WP_096410503.1|117624_118845_+|IS256-family-transposase
MFNRGAHLSTRRCPVDQDTLRILLREAVRETVAEVLQTVLELDRTAFLQVHGGRRNGYYPRKLETTFGQVDLKVPRDRESRYYPAFLKPYARRLVDVGEVAVALYAAGVSQRKAAEILSLLLGHRYSHETLSALTDQVLEAAGAFRTRPLPEEMAFVYLDGLSLKVFREGEGIVRETVYVALGIAPDGERRVLGFWLLPTESALGWEGVLGELWQRGLRRVLLFITDGLPGLPEAIRRVYPQAEWQRCVVHGVRWSLSQVRARDRGLLAEDLRRVYGAESRDEALRALEEVKAAWGSRYPGVVGLWVQDSGAFLRFYGYPKVLWPYLRSTNLMERFIRELRRGTKVRDHKFPKEEAVYKLLYLESERQEGRWAERKLKGFSEVKEVLEKMLQERYAPRTQTLTHNS
>NZ_AP017920.1|WP_096410504.1|118752_119241_-|ABC-transporter-substrate-binding-protein
MVVGSAFHGLGKAQSGTIKIGFVSPRTGPLAAFAQPDDFTLEQVRKATGGKVRVGGKTYNLEIVYKDSQSNPNRAAEVTAELILKDRVHLVVAGNTPETTVPVADQCELNGIPCITDDTPWQPYFFSRGGVVSRVMCKSLCTGGIPLLKHLLQHLLHLREPL
>NZ_AP017920.1|WP_096410505.1|119345_120320_-|catechol-2,3-dioxygenase
MKPEPIFDVHQLAHVEIYTPNPEGTLWFFRDLLGMEVTKQEGQSVYMRAYEDWYHHTLKITEAPKPGLGHVAWRTSSPQALERRVKALEATGLGKGWIDGDLGHGPAYRFTTPDGHPMELLWEVEYYEPPEDKKTPLLNRPQKRPLRGVPVRRLDHVNLLASDVTVNKNFMMEHLGFRLREHIVMKDGTEAGAWISVSPLVHEIAFMRDGKGAKGRLHHVCYWYGYPHDLNTLADIFREVGIKIEAGPGKHGISQAMFMYVLEPGGNRVELFGDPGYLIFDPDWKPIKWTEETLEAGIIWYGSPLPAEFFLYGTPEVEEQVAAD
>NZ_AP017920.1|WP_096410506.1|120520_122086_-|Pyoverdin-chromophore-biosynthetic-protein-pvcC
MNEQVRERLKALTRPMTGEEYLESLRDGREVYFMGERVKDVTTHPAFRNTARMFARWYDRLHELHKEDLERSKDPSGWKWTVPTEFGNGWTHPFFVGPRSAEDLLKARDTIAELQRTVYGWGGRSPDYKAAFVGTLGPNAEFYAPYQENARRWYRETQEKLLYWNHAIVNPPVDRHKPVEEVGDVYMHVERETDAGLVVSGAKVVATGSAFTHVNFIAHYGPLPIKDKKFALIFVVPMDAKGVKLISRASYEFIAARTGSPFDYPLSSRLDENDAILVFDNVLVPWENVFVYGDVEKVNAFFPLSGFVHRFPFQGCTRFAVKLDFIAGLMMKALDVTGVSQFRGVQARLGEVLTYRNLFWALTEAMARDPMPWVDGYVLPNLWAGLTYRVLAPEVYPKVKDIIERDLASALIYLPSHAKDFQNPEIRRYLDQYVRGNGVDAVTRVKIMKALWDAVGTEFGGRHELYERNYAGNHENIRIETLGAMEAAGVNEALRAFAEKFLGEYDLEGWKVPDLINPTEA
>NZ_AP017920.1|WP_096410507.1|123134_124058_+|acetaldehyde-dehydrogenase-(acetylating)
MSDKVKVAILGSGNIGTDLMYKLLKNPGHMELVALVGIDPNSEGLARARALGLEASHEGIAYILERPEIKIVFDATSAKAHVRHAKLLREAGKIAIDLTPAARGPYVVPPVNLKAHLDQDNVNLITCGGQATIPLVYAVHRVAPVRYAEMVSTVASRSAGPGTRQNIDEFTFTTARGLEAIGGAKRGKAIIILNPAEPPILMTNTVRCIPEDEAFDREAVVASVRAMEREVQAYVPGYRLKADPVFERLPTPWGERTVVSMLLEVEGAGDYLPKYAGNLDIMTASARRVGEVFAQHLLGKPAEEVVA

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Crispr_ID: NZ_AP017920_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017920_3

367836-368258

Orphan

III-A

Consensus_repeat	Method
GGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	CRISPRCasFinder
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	CRT
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	PILER-CR

5 spacers

The CRISPR arrays of NZ_AP017920_3

>merge|NZ_AP017920|3|367836-368258|CRISPRCasFinder,CRT,PILER-CR
AGTATCAATCCCCTTACGGGGCTCAAGCTCTTGCAACCCCGTGGGCCCGCAGGGTCCCGGGGTGGGCTATTACTGGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAACCGGGCGGATGAAGCCATCCGCCCGGTCGCCCTTCCCTGGGGGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAACGCCTACCACGTGGCCCTCCTCAGGCCCAAAAGCGGCCTCTAGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAACGCTCCTTCGTGGTCCTCCGGGGCCGGTACCGCCTGGAGAGCTAGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAACTGCGGAGGCGGGCGCGCCGGAGCGGGAGGACGGAGGTGGTCTAGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC

>NZ_AP017920|3|3|367836-368258|CRISPRCasFinder
AGTATCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	CCCGTGGGCCCGCAGGGTCCCGGGGTGGGCTATTACT
GGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	CGGGCGGATGAAGCCATCCGCCCGGTCGCCCTTCCCTGGG
GGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	GCCTACCACGTGGCCCTCCTCAGGCCCAAAAGCGGCCTCT
AGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	GCTCCTTCGTGGTCCTCCGGGGCCGGTACCGCCTGGAGAGCT
AGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	TGCGGAGGCGGGCGCGCCGGAGCGGGAGGACGGAGGTGGTCT
AGTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC

>NZ_AP017920|3|3|367837-368258|CRT
GTATCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	CCCGTGGGCCCGCAGGGTCCCGGGGTGGGCTATTACTG
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	CGGGCGGATGAAGCCATCCGCCCGGTCGCCCTTCCCTGGGG
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	GCCTACCACGTGGCCCTCCTCAGGCCCAAAAGCGGCCTCTA
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	GCTCCTTCGTGGTCCTCCGGGGCCGGTACCGCCTGGAGAGCTA
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	TGCGGAGGCGGGCGCGCCGGAGCGGGAGGACGGAGGTGGTCTA
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC

>NZ_AP017920|3|3|367911-368258|PILER-CR
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	CGGGCGGATGAAGCCATCCGCCCGGTCGCCCTTCCCTGGGG
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	GCCTACCACGTGGCCCTCCTCAGGCCCAAAAGCGGCCTCTA
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	GCTCCTTCGTGGTCCTCCGGGGCCGGTACCGCCTGGAGAGCTA
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	TGCGGAGGCGGGCGCGCCGGAGCGGGAGGACGGAGGTGGTCTA
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017920.1\|WP_172844620.1\|363362_363878_-\|RsmD-family-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|367574
NZ_AP017920.1\|WP_096410677.1\|365165_366461_+\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|131739
NZ_AP017920.1\|WP_172844622.1\|375252_375858_+\|biotin-transporter-BioY	unknown	unknown	gnl\|CDD\|224187
NZ_AP017920.1\|WP_096410678.1\|370969_372214_-\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|227325
NZ_AP017920.1\|WP_096410670.1\|359585_359837_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_AP017920.1\|WP_096410683.1\|376563_376998_+\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|235455
NZ_AP017920.1\|WP_096410681.1\|374145_375141_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NZ_AP017920.1\|WP_096410673.1\|362879_363362_-\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NZ_AP017920.1\|WP_096410676.1\|364553_365165_-\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|366476
NZ_AP017920.1\|WP_096410686.1\|382567_383254_-\|zinc-metallopeptidase	unknown	unknown	gnl\|CDD\|377289
NZ_AP017920.1\|WP_096410685.1\|382318_382567_-\|zf-TFIIB-domain-containing-protein	unknown	unknown	gnl\|CDD\|226331
NZ_AP017920.1\|WP_096410679.1\|372223_372622_-\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_AP017920.1\|WP_096410672.1\|360029_361328_+\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_AP017920.1\|WP_096410680.1\|372600_372888_-\|ribosome-binding-factor-A	unknown	unknown	gnl\|CDD\|223927
NZ_AP017920.1\|WP_096410669.1\|358311_359586_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607
NZ_AP017920.1\|WP_096410684.1\|381649_381976_+\|nucleoside-triphosphate-pyrophosphohydrolase-family-protein	unknown	unknown	gnl\|CDD\|212148
NZ_AP017920.1\|WP_096410671.1\|359826_360033_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017920.1\|WP_172844621.1\|366414_367527_+\|AmmeMemoRadiSam-system-protein-B	unknown	unknown	gnl\|CDD\|280116
NZ_AP017920.1\|WP_096410675.1\|364081_364585_+\|glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|376884
NZ_AP017920.1\|WP_096410682.1\|375854_376562_+\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143587

Protein	Function_ID	Function_description	E-value
NZ_AP017920.1\|WP_172844620.1\|363362_363878_-\|RsmD-family-RNA-methyltransferase	gnl\|CDD\|367574	pfam03602, Cons_hypoth95, Conserved hypothetical protein 95.	6.23498e-38
NZ_AP017920.1\|WP_096410677.1\|365165_366461_+\|HDIG-domain-containing-protein	gnl\|CDD\|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	5.68803e-50
NZ_AP017920.1\|WP_172844622.1\|375252_375858_+\|biotin-transporter-BioY	gnl\|CDD\|224187	COG1268, BioY, Uncharacterized conserved protein [General function prediction only].	1.4978e-38
NZ_AP017920.1\|WP_096410678.1\|370969_372214_-\|aspartate-aminotransferase-family-protein	gnl\|CDD\|227325	COG4992, ArgD, Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism].	0
NZ_AP017920.1\|WP_096410670.1\|359585_359837_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	4.96022e-06
NZ_AP017920.1\|WP_096410683.1\|376563_376998_+\|SsrA-binding-protein-SmpB	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	8.02824e-74
NZ_AP017920.1\|WP_096410673.1\|362879_363362_-\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	8.79402e-102
NZ_AP017920.1\|WP_096410676.1\|364553_365165_-\|dephospho-CoA-kinase	gnl\|CDD\|366476	pfam01121, CoaE, Dephospho-CoA kinase. This family catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form Coenzyme A EC:2.7.1.24. This enzyme uses ATP in its reaction.	9.95863e-78
NZ_AP017920.1\|WP_096410686.1\|382567_383254_-\|zinc-metallopeptidase	gnl\|CDD\|377289	pfam04298, Zn_peptidase_2, Putative neutral zinc metallopeptidase. Zinc metallopeptidase zinc binding regions have been predicted in some family members by a pattern match (Prosite:PS00142), of the characteristic HEXXH motif.	3.29598e-109
NZ_AP017920.1\|WP_096410685.1\|382318_382567_-\|zf-TFIIB-domain-containing-protein	gnl\|CDD\|226331	COG3809, COG3809, Uncharacterized protein conserved in bacteria [Function unknown].	3.6492e-22
NZ_AP017920.1\|WP_096410681.1\|374145_375141_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	1.3109e-178
NZ_AP017920.1\|WP_096410672.1\|360029_361328_+\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_AP017920.1\|WP_096410680.1\|372600_372888_-\|ribosome-binding-factor-A	gnl\|CDD\|223927	COG0858, RbfA, Ribosome-binding factor A [Translation, ribosomal structure and biogenesis].	3.65227e-11
NZ_AP017920.1\|WP_096410669.1\|358311_359586_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
NZ_AP017920.1\|WP_096410684.1\|381649_381976_+\|nucleoside-triphosphate-pyrophosphohydrolase-family-protein	gnl\|CDD\|212148	cd11541, NTP-PPase_u4, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea. This family corresponds to a group of uncharacterized hypothetical proteins from bacteria, showing a high sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, members in this family consist of a single MazG-like domain that contains a well conserved divalent ion-binding motif EXX[E/D].	5.00657e-33
NZ_AP017920.1\|WP_096410679.1\|372223_372622_-\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	5.52713e-33
NZ_AP017920.1\|WP_172844621.1\|366414_367527_+\|AmmeMemoRadiSam-system-protein-B	gnl\|CDD\|280116	pfam01875, Memo, Memo-like protein. This family contains members from all branches of life. The molecular function of this protein is unknown, but Memo (mediator of ErbB2-driven cell motility) a human protein is included in this family. It has been suggested that Memo controls cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton.	2.95057e-86
NZ_AP017920.1\|WP_096410675.1\|364081_364585_+\|glycerol-3-phosphate-acyltransferase	gnl\|CDD\|376884	pfam02660, G3P_acyltransf, Glycerol-3-phosphate acyltransferase. This family of enzymes catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate to form lysophosphatidic acid.	9.57962e-11
NZ_AP017920.1\|WP_096410682.1\|375854_376562_+\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143587	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes. This superfamily (also known as the C-N hydrolase superfamily) contains hydrolases that break carbon-nitrogen bonds; it includes nitrilases, cyanide dihydratases, aliphatic amidases, N-terminal amidases, beta-ureidopropionases, biotinidases, pantotheinase, N-carbamyl-D-amino acid amidohydrolases, the glutaminase domain of glutamine-dependent NAD+ synthetase, apolipoprotein N-acyltransferases, and N-carbamoylputrescine amidohydrolases, among others. These enzymes depend on a Glu-Lys-Cys catalytic triad, and work through a thiol acylenzyme intermediate. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. These oligomers include dimers, tetramers, hexamers, octamers, tetradecamers, octadecamers, as well as variable length helical arrangements and homo-oligomeric spirals. These proteins have roles in vitamin and co-enzyme metabolism, in detoxifying small molecules, in the synthesis of signaling molecules, and in the post-translational modification of proteins. They are used industrially, as biocatalysts in the fine chemical and pharmaceutical industry, in cyanide remediation, and in the treatment of toxic effluent. This superfamily has been classified previously in the literature, based on global and structure-based sequence analysis, into thirteen different enzyme classes (referred to as 1-13). This hierarchy includes those thirteen classes and a few additional subfamilies. A putative distant relative, the plasmid-borne TraB family, has not been included in the hierarchy.	1.0009e-41

>NZ_AP017920.1|WP_172844621.1|366414_367527_+|AmmeMemoRadiSam-system-protein-B
MEGRLRLREPQITPVEGGFLVSDPYGVYEKPLALTEGGLFLLSLMEGRTLEEVQEEVFKRHGVLVPRKELEELAKALEEAGLLLTERVEARLREEEERLRRERPMRLAGLSYPKGEREARAFLEAFRASYPGEGREAKVLLMPHLEPSRVPEVYGAALAALEKTPPPERVYLVGVAHRPLKERAAALPVPFQTPFGPALPDLPALQALDALLPFELFNTPLAFREEHSLELPLFFLKGRFPEARVLPLLVGRRSPELGEALKVVLRDFPGLLVLAVDLSHVGPRFGDPPLTRPLAEEARRRDLGFLERIAEGAPEAALALLGENPTRIDGVEVVASLLPLLRGRRGEVLAHRLDLEAPTLSAVGAGTLVL
>NZ_AP017920.1|WP_096410677.1|365165_366461_+|HDIG-domain-containing-protein
MDFPFYTPKDAFPVGGAVRDLLLGRRPKDLDYAALDPQKAAEEAQRRLGGSLFPLDPERGHFRLVVGERTLDFTPLEGTPEGDLLRRDYRLNALLWKGGAVFGLEGVEEDLRRRLLVPVREENLYQDHLRSLRGVRLSATLGFGLPRRTREALGRHARFLQAHPEAIPARERVREELARLLLSPKAAYGLRLLERVGLLGVYLPELALLVGLHQGGVHHLPVWEHTLSVVFHLLWLWPEAPLEARLAALFHDVGKPLTRRFDPEVGRFRFLGHAEVGAEIARASLLWLRFPKEAVERVAGLVRRHMDRPPEERKALRRFLLKRQDLLPDLVYLMAADRLAAKGVEAEAWEVLGRYGEALKDPLPQRPLLSGEEVMALLGLREGPEVGRALKALLEAQAEGRVGTEEEARAFLLYWKGGREAQASGTPDHPR
>NZ_AP017920.1|WP_096410676.1|364553_365165_-|dephospho-CoA-kinase
MADQPEHPIIIGITGNIGSGKSTVAALLRAWGYPVLDLDALAARARENKEAELRRLFPEAFPEGRLDRRALARLVFSDPEKLKALEAVVHPEVGRLLGEELSRLEAPLVFLEVPLLFEKGWEGRLHGTLLVTAPLEVRVRRVMARSGLSREEVLARERAQMPEEEKRRRATWVLENTGSLEDLERALKAVLAQLTGGAKGGPG
>NZ_AP017920.1|WP_096410675.1|364081_364585_+|glycerol-3-phosphate-acyltransferase
MAAAVLAGYLMGSLPFAFWFAALQGKGWSGREPLWRLGPVPAGLVLLLDFAKGVFAVALGEFLARDYTGGLAAGAAAAFAHALSPWLGLRRAGSLLAPLGVLFAVDPRLLLLAGLPAGVLLLAGRQAYPALLAFALALPLAALLLGGGQAHLLFALALSLALLWPPR
>NZ_AP017920.1|WP_172844620.1|363362_363878_-|RsmD-family-RNA-methyltransferase
MVRILGGKARGVALKVPASARPSPVRLRKALFDYLRLRYPRRGRFLDLFAGSGAVGLEAASEGWEAVLVEKDPEAVQLLKENVRRTGLGARVVALPVEVFLPEAKARGERFTVAFMAPPYAMDLAALFGELLASGLVEAGGLYVLQHPKDLYLPLGERRVYGENALTLVEV
>NZ_AP017920.1|WP_096410673.1|362879_363362_-|pantetheine-phosphate-adenylyltransferase
MHVVYPGSFDPLTNGHLDVIQRASRLFEKVTVAVLENPSKRGQYLFSAEERLAIIREATAHLANVEAATFSGLLVDFVRRVGAQAIVKGLRAVSDYEYELQMAHLNRQLYPGLETLFILAATRYSFVSSTMVKEIARYGGDVSKLVPPATLRALKAKFGR
>NZ_AP017920.1|WP_096410672.1|360029_361328_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MNLKDPICAIATPPGKGAIGVVRLSGEGALEIAARVWRGKDPRRLKGGRFTLGEVVDPRTGEAIDQALLLVFRAPRSYTGEDLVEFQTHGSLAVLRRVMEVLVAEGARPAGRGEFTFRAYMNGKLDLAQAEAVLALVEAEGELARRQALRALEGALSRRIEALENRLLDLLAHIQALLDYPEEGVEPLEAERTIREVLAEVEALLAQAKASRLAQKGARLALIGAPNAGKSSLLNALLGYERALVSPIPGTTRDYLEAPLELFGIPLVAVDTAGVRETEDPLERMGVERALRIAEEADLVLYVVDRSQPKPAPPPLPWARTLKVATKSDLPPAWEDPEFLPVSSLTGEGLDRLKEALREALLGREGGEVLLTERQVEALLRAKARLEEALALPEDLMGLALEEAAWALALLTGKEVAEEVVARVFQNFCVGK
>NZ_AP017920.1|WP_096410671.1|359826_360033_+|hypothetical-protein
MRLKVLVEYHPELEGEHEPYVARILDYPELQGYGFTPEEALQDALAFLEEHLGRPLKVIREEVQVDVA
>NZ_AP017920.1|WP_096410670.1|359585_359837_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MGGREELLARVRARVARCSWEDFLRLAEAYGFSLHVGKGSRRRLVHSTGVVVSVHEPHPRSKPVHPEAVKALLRAIRRLEDEA
>NZ_AP017920.1|WP_096410669.1|358311_359586_+|glutamate-1-semialdehyde-2,1-aminomutase
MERPISEAYFQEAKRHIPGGVSSPVRAFKAVGGTPPFLVRGEGAYVWDADGNRYLDYVMSWGPLILGHAHPKVLARVRETLERGLTFGAPSPLEVALAKKVKRAYPFVDLVRFVNSGTEATMSALRLARGYTNRPYIVKFRGNYHGHADGLLVEAGSGALTLGVPSSAGVPEEYAKLTLVLEYNDPEGLREVLRRRGEEIAAIIFEPVVGNAGVLVPTEEFLKALHEAREFGVLLIADEVMTGFRLAFGGATELLGLKPDLVTLGKILGGGLPAAAYAGRREIMEKVAPLGPVYQAGTLSGNPLAMAAGLATLELLEENPGYYRYLEDLGARLERGLKEVLAQKGIPHAVNRVGSMITVFFTEGPVVTFQDAKRTDTELFKRFFHGLLDRGIYWPPSNFEAAFLSVAHTEEDVEKTLEALEDAL
>NZ_AP017920.1|WP_096410678.1|370969_372214_-|aspartate-aminotransferase-family-protein
MDLDAFTLFERHINPGLAGLLRFTGLDRVESHAEGPYVWDTQGKRYLDFLGLYGTLNLGHRHPKVVEAVKRQLDRMPMSVRVLVSEPTARLAARLAEITPEGLEMVFFGNSGAEAVEAAIKLARAYTGKPGIITTQGGFHGKTMGALSLTPKPEYQDPARPLLPGVKAVPYGDLKALEEAIDEDTAAVIVEPIQGEGGIRVPPEGYLRGVRELTREKGVLMIADEVQTGLGRTGKLFGVDWEGVSPDLMTLAKALGGGVMPIGACVGRREVFEVFKTNPLFHSSTFGGNPLAAAAALAAIEVTLEEDLPGRALELGRHLMAGLKALKEEHPHLIEDVRGRGLMLGVEFTDADIGALVVAEMAERGVLTAFGLNNPKVVRLEPPLIIGKEHVDEALAVFAEALKATEKALEGLLG
>NZ_AP017920.1|WP_096410679.1|372223_372622_-|acyl-CoA-thioesterase
MESLTRIKVRYAETDQMGVVHHAVYAVYLEAARVDFLERAGLPYHLVEARGVFFPVVELGLTFRAPARFGEEVEVRTRLAELSSRALLFRYRVEREGVLLAEGFTRHLCQVGGRAARIPEDLYRALSVLHLR
>NZ_AP017920.1|WP_096410680.1|372600_372888_-|ribosome-binding-factor-A
MAYGKAHLEARLKRALAEEIQALEDPRLFLLTVEAVRLSEDGSILSVYVEAFREEEGALRALSRAERRLVAALARRVRLRRLPRLEFLPWRASPA
>NZ_AP017920.1|WP_096410681.1|374145_375141_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MKVGINGFGRIGRQVFRILHERGVEVALVNDLTDNKTLAHLLKYDSTYGRFPGEVGYDEENLYVDGKAIRATAIKDPREIPWKEAGVGVVVESTGVFTDGEKARAHLEAGAKKVIITAPAKGEDITVVLGVNHEQYDPARHHILSNASCTTNSLAPVMKVLEEAFGVEKALMTTVHSYTNDQRLLDLPHKDLRRARAAAINIIPTTTGAAKATALVLPSLKGRFDGMALRVPTPTGSISDITALLKREVTAEEVNAALKAAAEGPLKGILAYTEDEIVLQDIVMDPHSSIVDGKLTKAIGNLVKVFAWYDNEWGYANRVADLVELVLKKGV
>NZ_AP017920.1|WP_172844622.1|375252_375858_+|biotin-transporter-BioY
MKTEVLPYTPLMKTLWPQRTLARDLLLILAGSLFVALTAQIALPLPFTPVPITGQTLGVLLVGAALGSRLGFLALLAYLLEGAMGLPVFAGGTGGIARILGPTGGFLLAFPLAAGLVGLLVERFGLDRGFFGTLLAMLLGNALLYLVGLPWLAAWLMGAGKFTGVEGLLAMGLFPFIPGDLVKAVLAALLLPTAWRFLGRK
>NZ_AP017920.1|WP_096410682.1|375854_376562_+|carbon-nitrogen-hydrolase-family-protein
MILALAHLAKRERLREFLQALRPLVQEAKERGAGLLLLPELVLGKREDPGLSQALRELAEEARLLLLAGHLAEGENRLQAFPQGPAYAKLHLYRAEGEEGDEGLRPGKRPVLLPWGGKVFGLALCYDLDFPELFRAYALRGAQGFLVGAAWPGAYAGLLEVLARARAAENQAYLFLASRADTGSPSLFVAPDGRVLARKEEEGLLVAEPDWAFLEAYRKKYPLLQHRREDLHRLW
>NZ_AP017920.1|WP_096410683.1|376563_376998_+|SsrA-binding-protein-SmpB
MAPVLENRRARHDYEILETYEAGIALKGTEVKSLRAGKVDFTGSFAKFEDGELYLENLYIAPYEKGSYTNVDPRRKRKLLLHKHELRRLLGKVEQRGLTLVPLKIYFNERGYAKVLLGLARGKKAYEKRREDKKEAVRRALEEL
>NZ_AP017920.1|WP_096410684.1|381649_381976_+|nucleoside-triphosphate-pyrophosphohydrolase-family-protein
MTFEEYQKEAQKTALYPEAYRLVYPALGLAGEAGELANKVKKVLRDHGGRLREEDREAILAELGDVLWYVAQVATDLGESLEAVAQANLAKLRSRKERGRLGGAGDNR
>NZ_AP017920.1|WP_096410685.1|382318_382567_-|zf-TFIIB-domain-containing-protein
MPLLLCPHCGVGMREVERRGVLIDVCPQCGGVWLDKGELEKLLAEAKEVERGYEEELEGFYRKEGKPYKKKKGFLELFDLFD
>NZ_AP017920.1|WP_096410686.1|382567_383254_-|zinc-metallopeptidase
MDTLAFLLMILVFVASLAIQGGLQATFARYSRVANSRGLTGAEVARAILDTHGLTHVRVEPVPGALTDHYDPQAKAVRLSEPNYASPSLAALAVAAHEVGHAVQDARGYAWLRVRASLWPAASLGSNLGPILVLAGLFLGALGLAKLGLYLYLAVALFQLITLPVEFDASRRALEFLRRMGFLRPEEMGPARRVLTWAALTYVAALAGSLATILYYASLLGLFGRREE

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Crispr_ID: NZ_AP017920_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017920_4

1161766-1163871

Orphan

Consensus_repeat	Method
GTTTCAAACCCTCATAGGTACGGTCAAAAG	PILER-CR
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CRISPRCasFinder
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CRT

31 spacers

The CRISPR arrays of NZ_AP017920_4

>merge|NZ_AP017920|4|1161766-1163871|PILER-CR,CRISPRCasFinder,CRT
CTTTTGACCGTACCTATGAGGGTTTGAAACAATACGCCCTGGCCTGGGAGGGCCTAGGGGTGCGCACCTTTTGACCGTACCTATGAGGGTTTGAAACTGGTACGGGACTGCCCGAAGTATCTCCGCCACAGGAACCTTTTGACCGTACCTATGAGGGTTTGAAACCCTGCCCACCTGGTCCGACGAGGAGCTGGAAGAGTGGGCTTTTGACCGTACCTATGAGGGTTTGAAACTTCAAGTCGGATGGCTGGTTCACCATTCCGAGGCTGCTTTTGACCGTACCTATGAGGGTTTGAAACAGCCAAATGTCCTGCCCACCCTCTTCATCGGGGGCTTTTGACCGTACCTATGAGGGTTTGAAACTAGCATTACCAGTCGGTTTTGCAAAGTCCCACCCCTCTTCTTTTGACCGTACCTATGAGGGTTTGAAACAGCCCCGCGAAGGCCCAGGGGGGCACCCCCAGGGCCCTTTTGACCGTACCTATGAGGGTTTGAAACATGGGGAGTGGAGTTTCGGCGAGCGTGGTTTCTAGGCGCTTTTGACCGTACCTATGAGGGTTTGAAACAGCGTCACGGTCACGAGGTTGGAGGAGGTCCGCTTTTGACCGTACCTATGAGGGTTTGAAACCGTGAATAGCTCCCACCCTTTCATGTGGTCCTCGCGAGCTCCTTTTGACCGTACCTATGAGGGTTTGAAACAAGGCCTGGGCGCTCCATGCCACCTGGCTGGACCTTCTTTTGACCGTACCTATGAGGGTTTGAAACAGGTCTTCGGGAGGGGGTGGGTGCGCCGCGTGGCCGCCCTTTTGACCGTACCTATGAGGGTTTGAAACCGAATAGCCATAGCGGCTTTCTCTTCTGTAGCCACCCTTTTGACCGTACCTATGAGGGTTTGAAACGCCGCCCTGGGCTCATCCCGAGGACTGGGAGGCTTCCTTTTGACCGTACCTATGAGGGTTTGAAACTTGAGGAGCCTATCTTCCGCCAGCAACTTAAGCATCGCTTTTGACCGTACCTATGAGGGTTTGAAACCCCTTTACGCCCGCAAGGACGCGGCGGACCAGCTCCGCTTTTGACCGTACCTATGAGGGTTTGAAACATCAATTCGGCAACTTGGCAAGAGGCTGAGCGGCTTCTTTTGACCGTACCTATGAGGGTTTGAAACCGCCTACCCCTCGGCCTCGCCGAGGGGCTTAAGCGCCCCTTTTGACCGTACCTATGAGGGTTTGAAACCTGGTAGACCTCAACCGAGCGGCGCCAGAAACCGGGCCTTTTGACCGTACCTATGAGGGTTTGAAACTTGCGGTTCCCCGGAGTGGCCTCCCGGGCGAACTCGTCTTTTGACCGTACCTATGAGGGTTTGAAACAGGAACTGGTGGGGGTGCTCAAGGCTCTCACCGCGGCCCCTTTTGACCGTACCTATGAGGGTTTGAAACGCCCCACAAGTGGAAAGCCTTATGGCCCGCGCCCTGGCTTTTGACCGTACCTATGAGGGTTTGAAACTTAGTAGAGATTCTCCGTCTCCTCCAATGCACTTTGCTTTTGACCGTACCTATGAGGGTTTGAAACCCTCAAAGGCAATCTCCGGGGCGATGCTATAAACCTTGCTTTTGACCGTACCTATGAGGGTTTGAAACCGCAGAGTTCCCCCCGGAGGGGGGTCCCCCCAGAAGCTTTTGACCGTACCTATGAGGGTTTGAAACTTTTTTTCCTTCATCTCCTCCTCCTTTCCCCCTGGCTTTTGACCGTACCTATGAGGGTTTGAAACAGTTCTCCCTCGATCCACCAGCGGTGCTTCACGTTTCCCCTTTTGACCGTACCTATGAGGGTTTGAAACTCTTTAGGGGGGGTTATAGGGGGGGAGGTGGGAGATTTCTTTTGACCGTACCTATGAGGGTTTGAAACTTTGCTGCCAATAGATTGCGTCACGAGCGGCCCCCACCTTTTGACCGTACCTATGAGGGTTTGAAACTTGTAGTCCACGGACTGGATGATGCACCGCTGCCACACCTTTTGACCGTACCTATGAGGGTTTGAAACCCGGGTATAAGACCCACTCCGATTATGGGCCCGGTCGTTTTGACCGTACCTATGAGGGTTTGATAA

>NZ_AP017920|4|4|1161766-1163805|PILER-CR
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AATACGCCCTGGCCTGGGAGGGCCTAGGGGTGCGCAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TGGTACGGGACTGCCCGAAGTATCTCCGCCACAGGAAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGCCCACCTGGTCCGACGAGGAGCTGGAAGAGTGGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTCAAGTCGGATGGCTGGTTCACCATTCCGAGGCTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCCAAATGTCCTGCCCACCCTCTTCATCGGGGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TAGCATTACCAGTCGGTTTTGCAAAGTCCCACCCCTCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCCCCGCGAAGGCCCAGGGGGGCACCCCCAGGGCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	ATGGGGAGTGGAGTTTCGGCGAGCGTGGTTTCTAGGCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCGTCACGGTCACGAGGTTGGAGGAGGTCCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGTGAATAGCTCCCACCCTTTCATGTGGTCCTCGCGAGCTC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AAGGCCTGGGCGCTCCATGCCACCTGGCTGGACCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGTCTTCGGGAGGGGGTGGGTGCGCCGCGTGGCCGCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGAATAGCCATAGCGGCTTTCTCTTCTGTAGCCACC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	GCCGCCCTGGGCTCATCCCGAGGACTGGGAGGCTTC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGAGGAGCCTATCTTCCGCCAGCAACTTAAGCATCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCCTTTACGCCCGCAAGGACGCGGCGGACCAGCTCCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	ATCAATTCGGCAACTTGGCAAGAGGCTGAGCGGCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGCCTACCCCTCGGCCTCGCCGAGGGGCTTAAGCGCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CTGGTAGACCTCAACCGAGCGGCGCCAGAAACCGGGC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGCGGTTCCCCGGAGTGGCCTCCCGGGCGAACTCGT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGAACTGGTGGGGGTGCTCAAGGCTCTCACCGCGGCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	GCCCCACAAGTGGAAAGCCTTATGGCCCGCGCCCTGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTAGTAGAGATTCTCCGTCTCCTCCAATGCACTTTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTCAAAGGCAATCTCCGGGGCGATGCTATAAACCTTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGCAGAGTTCCCCCCGGAGGGGGGTCCCCCCAGAAG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTTTTTTCCTTCATCTCCTCCTCCTTTCCCCCTGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGTTCTCCCTCGATCCACCAGCGGTGCTTCACGTTTCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TCTTTAGGGGGGGTTATAGGGGGGGAGGTGGGAGATTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTTGCTGCCAATAGATTGCGTCACGAGCGGCCCCCAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGTAGTCCACGGACTGGATGATGCACCGCTGCCACAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC

>NZ_AP017920|4|4|1161766-1163871|CRISPRCasFinder
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AATACGCCCTGGCCTGGGAGGGCCTAGGGGTGCGCAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TGGTACGGGACTGCCCGAAGTATCTCCGCCACAGGAAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGCCCACCTGGTCCGACGAGGAGCTGGAAGAGTGGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTCAAGTCGGATGGCTGGTTCACCATTCCGAGGCTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCCAAATGTCCTGCCCACCCTCTTCATCGGGGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TAGCATTACCAGTCGGTTTTGCAAAGTCCCACCCCTCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCCCCGCGAAGGCCCAGGGGGGCACCCCCAGGGCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	ATGGGGAGTGGAGTTTCGGCGAGCGTGGTTTCTAGGCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCGTCACGGTCACGAGGTTGGAGGAGGTCCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGTGAATAGCTCCCACCCTTTCATGTGGTCCTCGCGAGCTC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AAGGCCTGGGCGCTCCATGCCACCTGGCTGGACCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGTCTTCGGGAGGGGGTGGGTGCGCCGCGTGGCCGCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGAATAGCCATAGCGGCTTTCTCTTCTGTAGCCACC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	GCCGCCCTGGGCTCATCCCGAGGACTGGGAGGCTTC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGAGGAGCCTATCTTCCGCCAGCAACTTAAGCATCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCCTTTACGCCCGCAAGGACGCGGCGGACCAGCTCCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	ATCAATTCGGCAACTTGGCAAGAGGCTGAGCGGCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGCCTACCCCTCGGCCTCGCCGAGGGGCTTAAGCGCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CTGGTAGACCTCAACCGAGCGGCGCCAGAAACCGGGC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGCGGTTCCCCGGAGTGGCCTCCCGGGCGAACTCGT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGAACTGGTGGGGGTGCTCAAGGCTCTCACCGCGGCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	GCCCCACAAGTGGAAAGCCTTATGGCCCGCGCCCTGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTAGTAGAGATTCTCCGTCTCCTCCAATGCACTTTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTCAAAGGCAATCTCCGGGGCGATGCTATAAACCTTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGCAGAGTTCCCCCCGGAGGGGGGTCCCCCCAGAAG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTTTTTTCCTTCATCTCCTCCTCCTTTCCCCCTGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGTTCTCCCTCGATCCACCAGCGGTGCTTCACGTTTCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TCTTTAGGGGGGGTTATAGGGGGGGAGGTGGGAGATTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTTGCTGCCAATAGATTGCGTCACGAGCGGCCCCCAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGTAGTCCACGGACTGGATGATGCACCGCTGCCACAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCGGGTATAAGACCCACTCCGATTATGGGCCCGGTC
GTTTTGACCGTACCTATGAGGGTTTGATAA

>NZ_AP017920|4|4|1161766-1163871|CRT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AATACGCCCTGGCCTGGGAGGGCCTAGGGGTGCGCAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TGGTACGGGACTGCCCGAAGTATCTCCGCCACAGGAAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTGCCCACCTGGTCCGACGAGGAGCTGGAAGAGTGGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTCAAGTCGGATGGCTGGTTCACCATTCCGAGGCTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCCAAATGTCCTGCCCACCCTCTTCATCGGGGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TAGCATTACCAGTCGGTTTTGCAAAGTCCCACCCCTCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCCCCGCGAAGGCCCAGGGGGGCACCCCCAGGGCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	ATGGGGAGTGGAGTTTCGGCGAGCGTGGTTTCTAGGCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGCGTCACGGTCACGAGGTTGGAGGAGGTCCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGTGAATAGCTCCCACCCTTTCATGTGGTCCTCGCGAGCTC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AAGGCCTGGGCGCTCCATGCCACCTGGCTGGACCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGTCTTCGGGAGGGGGTGGGTGCGCCGCGTGGCCGCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGAATAGCCATAGCGGCTTTCTCTTCTGTAGCCACC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	GCCGCCCTGGGCTCATCCCGAGGACTGGGAGGCTTC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGAGGAGCCTATCTTCCGCCAGCAACTTAAGCATCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCCTTTACGCCCGCAAGGACGCGGCGGACCAGCTCCG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	ATCAATTCGGCAACTTGGCAAGAGGCTGAGCGGCTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGCCTACCCCTCGGCCTCGCCGAGGGGCTTAAGCGCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CTGGTAGACCTCAACCGAGCGGCGCCAGAAACCGGGC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGCGGTTCCCCGGAGTGGCCTCCCGGGCGAACTCGT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGGAACTGGTGGGGGTGCTCAAGGCTCTCACCGCGGCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	GCCCCACAAGTGGAAAGCCTTATGGCCCGCGCCCTGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTAGTAGAGATTCTCCGTCTCCTCCAATGCACTTTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCTCAAAGGCAATCTCCGGGGCGATGCTATAAACCTTG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CGCAGAGTTCCCCCCGGAGGGGGGTCCCCCCAGAAG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTTTTTTCCTTCATCTCCTCCTCCTTTCCCCCTGG
CTTTTGACCGTACCTATGAGGGTTTGAAAC	AGTTCTCCCTCGATCCACCAGCGGTGCTTCACGTTTCCC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TCTTTAGGGGGGGTTATAGGGGGGGAGGTGGGAGATTT
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTTGCTGCCAATAGATTGCGTCACGAGCGGCCCCCAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	TTGTAGTCCACGGACTGGATGATGCACCGCTGCCACAC
CTTTTGACCGTACCTATGAGGGTTTGAAAC	CCGGGTATAAGACCCACTCCGATTATGGGCCCGGTC
GTTTTGACCGTACCTATGAGGGTTTGATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017920.1\|WP_096411234.1\|1154648_1154927_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017920.1\|WP_096411236.1\|1155332_1156430_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_AP017920.1\|WP_041444412.1\|1171475_1172621_+\|DNA-double-strand-break-repair-nuclease-NurA	unknown	unknown	gnl\|CDD\|214920
NZ_AP017920.1\|WP_157745802.1\|1175726_1176650_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NZ_AP017920.1\|WP_096411243.1\|1172644_1174486_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223510
NZ_AP017920.1\|WP_008633580.1\|1158769_1159027_-\|50S-ribosomal-protein-L27	unknown	unknown	gnl\|CDD\|235464
NZ_AP017920.1\|WP_096411235.1\|1154984_1155326_-\|ribosome-silencing-factor	unknown	unknown	gnl\|CDD\|272901
NZ_AP017920.1\|WP_157745843.1\|1156949_1157513_-\|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|234611
NZ_AP017920.1\|WP_096411239.1\|1160986_1161196_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NZ_AP017920.1\|WP_096411241.1\|1168443_1169907_+\|phosphodiester-glycosidase-family-protein	unknown	unknown	gnl\|CDD\|378342
NZ_AP017920.1\|WP_096413034.1\|1163892_1164087_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017920.1\|WP_008633581.1\|1159030_1159336_-\|50S-ribosomal-protein-L21	unknown	unknown	gnl\|CDD\|235510
NZ_AP017920.1\|WP_096411237.1\|1156429_1156975_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224627
NZ_AP017920.1\|WP_157745800.1\|1174824_1175151_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379267
NZ_AP017920.1\|WP_096411240.1\|1165331_1168208_+\|RtcB-family-protein	unknown	unknown	gnl\|CDD\|376465
NZ_AP017920.1\|WP_096413040.1\|1175388_1175697_+\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|320703
NZ_AP017920.1\|WP_096411238.1\|1157509_1158760_-\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237046
NZ_AP017920.1\|WP_096411242.1\|1169959_1171486_+\|DUF4338-domain-containing-protein	unknown	unknown	gnl\|CDD\|372975
NZ_AP017920.1\|WP_157745798.1\|1164342_1164870_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_AP017920.1\|WP_096411233.1\|1152694_1153801_-\|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl\|CDD\|225364

Protein	Function_ID	Function_description	E-value
NZ_AP017920.1\|WP_157745843.1\|1156949_1157513_-\|nicotinate-nucleotide-adenylyltransferase	gnl\|CDD\|234611	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase.	1.28341e-80
NZ_AP017920.1\|WP_096411236.1\|1155332_1156430_-\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	1.12557e-42
NZ_AP017920.1\|WP_041444412.1\|1171475_1172621_+\|DNA-double-strand-break-repair-nuclease-NurA	gnl\|CDD\|214920	smart00933, NurA, NurA nuclease. This family includes NurA a nuclease exhibiting both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double-stranded DNA from the hyperthermophilic archaeon Sulfolobus acidocaldarius.	4.04556e-25
NZ_AP017920.1\|WP_157745802.1\|1175726_1176650_+\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000416154
NZ_AP017920.1\|WP_096411243.1\|1172644_1174486_+\|ATP-binding-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	8.81813e-08
NZ_AP017920.1\|WP_157745798.1\|1164342_1164870_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	1.88561e-11
NZ_AP017920.1\|WP_096411235.1\|1154984_1155326_-\|ribosome-silencing-factor	gnl\|CDD\|272901	TIGR00090, rsfS_iojap_ybeB, ribosome silencing factor RsfS/YbeB/iojap. This model describes a widely distributed family of bacterial proteins related to iojap from plants. It includes RsfS(YbeB) from E. coli. The gene iojap is a pattern-striping gene in maize, reflecting a chloroplast development defect in some cells. The conserved function of this protein is to silence ribosomes by binding the ribosomal large subunit and impairing joining with the small subunit in response to nutrient stress. Note that RsfS (starvation) is an author-endorsed change from the published symbol RsfA, which conflicted with previously published gene symbols. [Protein synthesis, Translation factors].	1.51111e-43
NZ_AP017920.1\|WP_096411239.1\|1160986_1161196_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	9.35895e-06
NZ_AP017920.1\|WP_096411241.1\|1168443_1169907_+\|phosphodiester-glycosidase-family-protein	gnl\|CDD\|378342	pfam09992, NAGPA, Phosphodiester glycosidase. This is a family conserved from bacteria to humans. The structure of a member from Bacteroides has been crystallized and modelled onto the luminal region of the human member of the family, the transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. There is some conservation of potentially functional residues, implying that in the bacterial members this family acts in some way as a phosphodiester glycosidase. The human protein is also present, so the eukaryotic members are likely to be catalyzing the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides.	1.4987e-19
NZ_AP017920.1\|WP_008633581.1\|1159030_1159336_-\|50S-ribosomal-protein-L21	gnl\|CDD\|235510	PRK05573, rplU, 50S ribosomal protein L21; Validated.	6.80459e-47
NZ_AP017920.1\|WP_096411237.1\|1156429_1156975_-\|HD-domain-containing-protein	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	1.69394e-49
NZ_AP017920.1\|WP_157745800.1\|1174824_1175151_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|379267	pfam13565, HTH_32, Homeodomain-like domain.	3.47949e-08
NZ_AP017920.1\|WP_096411240.1\|1165331_1168208_+\|RtcB-family-protein	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	0
NZ_AP017920.1\|WP_096413040.1\|1175388_1175697_+\|M48-family-metallopeptidase	gnl\|CDD\|320703	cd07344, M48_yhfN_like, Peptidase M48 YhfN-like, a novel minigluzincin. M48 YhfN-like protease is considered as a CaaX prenyl protease 1 homolog, with most of the sequences in this family as yet uncharacterized. It contains the zinc metalloprotease motif (HEXXH), likely exposed on the cytoplasmic side. It is probably associated with the endoplasmic reticulum (ER), regardless of whether its genes possess the conventional signal motif (KKXX) in the C-terminal. Proteins in this family proteolytically remove the C-terminal three residues of farnesylated proteins. This novel family of related proteins consist of the soluble minimal scaffold similar to the catalytic domains of the integral-membrane metallopeptidase M48 and M56, thus called minigluzincins.	6.09581e-19
NZ_AP017920.1\|WP_096411238.1\|1157509_1158760_-\|GTPase-ObgE	gnl\|CDD\|237046	PRK12297, obgE, GTPase CgtA; Reviewed.	0
NZ_AP017920.1\|WP_096411242.1\|1169959_1171486_+\|DUF4338-domain-containing-protein	gnl\|CDD\|372975	pfam14236, DUF4338, Domain of unknown function (DUF4338). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 206 and 475 amino acids in length.	6.93959e-45
NZ_AP017920.1\|WP_008633580.1\|1158769_1159027_-\|50S-ribosomal-protein-L27	gnl\|CDD\|235464	PRK05435, rpmA, 50S ribosomal protein L27; Validated.	2.68826e-49
NZ_AP017920.1\|WP_096411233.1\|1152694_1153801_-\|type-IV-pilus-twitching-motility-protein-PilT	gnl\|CDD\|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	0

>NZ_AP017920.1|WP_096411239.1|1160986_1161196_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MTRRFTAHLWREGDLWVAQCLEVDVASQGETEEEALKNLKEALELYFEPPTPERAPVVRTVEVELGPAA
>NZ_AP017920.1|WP_008633581.1|1159030_1159336_-|50S-ribosomal-protein-L21
MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG
>NZ_AP017920.1|WP_008633580.1|1158769_1159027_-|50S-ribosomal-protein-L27
MAHKKGLGSTKNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA
>NZ_AP017920.1|WP_096411238.1|1157509_1158760_-|GTPase-ObgE
MFQDVLVITVAAGRGGDGAVSFRREKFVPKGGPDGGDGGRGGSVYLRARGSVDSLSRLSKRIYKAEDGEHGRGSQQHGRGGADLVIEVPRGTRVFDADTGELLADLTEEGQTVLVARGGAGGRGNMHFVTPTRQAPRFAEAGEEGEKRRLRLELMLIADVGLVGYPNAGKSSLLAAMTRAHPKIAPYPFTTLSPNLGVVEVSEEERFTLADIPGIIEGASEGKGLGLEFLRHIARTRVLLYVLDAADEPLKTLETLRKEVGAYDPALLRRPSLVALNKVDLLEEEAVKALADALAREGLAVLPVSALTGTGLPALKEALHALVRSTPPPEMPKPVPRKEVQAGVEVVPVAEGVYEVRAPEVERYLARIKGDLMEAAGYLQEVFRRQGVEAALRAKGVRAGDLVRIGGLEFEYIPEV
>NZ_AP017920.1|WP_157745843.1|1156949_1157513_-|nicotinate-nucleotide-adenylyltransferase
MSADRALRGSFDPIHLGHLLAASQAQEVLRLDRVLFVVAARPPHKVPVASAEARYEMTLLAVAEDPRFTVSRLELDRPGPSYTVDTLREARRLFPEDELFFITGADAYRDVLTWKEGERLPEYATLVAVARPGYPLEEAPLPVVPLFVPEVGISSTEIRRRLREGRSVRYWVPRAVEVYIEKHGLYR
>NZ_AP017920.1|WP_096411237.1|1156429_1156975_-|HD-domain-containing-protein
MKSTVSIADLEAKVQSLVRPERMEHIRRVAELAREIARNNGLDPERAYLAGLLHDAARDLPEEELRRLAPPENEVEEAHPLALHGRAARALAASWGVRDEEVLEAIEGHVYGVDPENGIGMALYVADVSEPGRGVNGEIRELALAGRLKEAYRLAVRNKVHYLKAKKIPIHPRTLEVYHSL
>NZ_AP017920.1|WP_096411236.1|1155332_1156430_-|LCP-family-protein
MRPRLSFFLLALALFALGGVLSWPRPAALSTSAPKRTGPVPEMGVVVAARDIDYCAPRTPCGPGSRTDTIFYVRVRGGEAVGVAVPRDLYSPLVGGKINAAYGRGGPELLKRAVEEATGLVAERHLVFTLEGVARVVDAVGGVEVYLDRPMRYVDRAANLYIDFPAGRLHLSGEEAVKYMRFRHDALGDYARLDRIKAVATQVARKAQDPRVWPALAAALREVWRELDTDLSLEEVLDYLPYARDFQVALATLPTREGAGTYLYVDEARRGELLSALFGGPPLTPPPGLPVRLRGDAGLIAWGRAFLEREGVEVWTEEAEVARSAVYATDPAVGRYYAGLFHLPVIAPHQPLAEVVVELGPDLLH
>NZ_AP017920.1|WP_096411235.1|1154984_1155326_-|ribosome-silencing-factor
MVKTKEAVALIQRIKELLAEKKAENVVALDLRRVSETLDYFVVASATSTPHLQALERHLLEKLEEEDLRPRPTAGQSPRWVVLDYGEVVVHLMTPEAREYYDLEGFWADAERL
>NZ_AP017920.1|WP_096411234.1|1154648_1154927_+|hypothetical-protein
MGKKKRQEKLKKKALKEWEARRPKTFRQFLPYLPGIFLRTTLVMTAAVTVIVVLGALGLPWAAHFWFQFAVYLAFYLAFQRFIMGPLAPPKV
>NZ_AP017920.1|WP_096411233.1|1152694_1153801_-|type-IV-pilus-twitching-motility-protein-PilT
MSEAQGQGKQSLVEMLKAMVQARASDIHLQAGAPPTVRIDGKLRPFGSRPLTPKDTEAIARALLTPEQLEELEYRKEMDFAYTIPGVARFRCNLLRQRGSLGLVMRVVSEVIPSFEALGLPREVMEGLAAKERGLILVTGPTGSGKSTTLAALIDHINLHYAKNIITIEDPIEFLHKHKKSLVVQREVGLDTDSFYTGLKYALRQDPDVIMVGEMRDKETVEAALMAAQTGHLVLSTLHTLDAWRTINRIIDFFPLHEHRQVRILLAESLLGILSQRLLPKADGQGRVLALEILIATPYVRELLKDEEKTPQIKEAMMEGSLYGMRTFDQHLVELYTEGLISLEDALSAATGPHEFRLLLTKATGQTY
>NZ_AP017920.1|WP_096413034.1|1163892_1164087_-|hypothetical-protein
MGRGSFCFWSWTRVWPLVDAVVANGRVETEEELWARVEARCAYLQTQPGLIRSHTLFHWWPGGC
>NZ_AP017920.1|WP_157745798.1|1164342_1164870_-|winged-helix-turn-helix-domain-containing-protein
MRLTKHQRRPRLELKLRHHPDNLHALYRESEDPVERARWHAIWLLATGHSIPQVAQTLGYSTRWVRNTLHRYNEGQPMADLRHQNPGQPPLLSPELQEAFRQALLQPHPQEGIWTIRNAALWLSERLGRPVDPRRAWTWMKRLGFAPLRPRPRHRERDVEEGEAFKKNSSSPLSS
>NZ_AP017920.1|WP_096411240.1|1165331_1168208_+|RtcB-family-protein
MRFEKIAPYTYRIPRQGKMRVDAVFFASKEILKDLEAENYASLQQLMNVATLPGIVEPALAMPDIHWGYGFPIGGVAAFDPEEGGVVSPGGVGFDINCLPPGTRILFRDGYTRPIEELAEERAPNLVVWRLGERPEAAQAALLLSREAEELLRLRTEGGFVLEATPDHPLYTPEGMRPAGALRPGDRVAVHPFRGLPYEPPPPLSLLEEEEAEAWARTLGFPQAPRELRARGLLPLRADHPHLPALLRLLGYAFGDGTLYRSGGRAYLVLYGEEEGLREAKADLERLGFRAGGPYLRRRNPTFRGRTFDAAEAGLKVSSRALFLLFRALGLPEGAKAKQGFRLPAWLFALPPWLKANFLAGLFGAELSAPKAVSGHEYNLVPPVLSQSKRRSFLEEGRAFTEDLARLVASLGLEVQDLREEADWEEPEDPSHRFKLILRSTPENLARLYEEVGYAYAPKKARLALLAALYLRLKQAHLARRESMAAEVLALREAGEKVAAIAHRLGVPRRFAERTLYEKRGAFRPQGLPTFPEFVAAQGAMLFDRVVAVERVPYGGKVYDLSMAHPDHNFVAEGFVVSNCGVRLLASHLTLEDLLPRQKELADALYRLVPSGVGSERRDVRFSKKELKEILKEGAGWLVKRGFGYPEDLGFIESQGRLPWANPDKVSERAFERGAPQIGTLGSGNHFLEVQYVDEVYDEEAAEAYGLFRGQVTVLIHTGSRGLGHQVCQDYVERFLKAAPRYGIELVDKQLAAAPIKSPEGQDYLQAMAAAANFAFANRQLIAHFVREAFEKVGFTPRDHGLRVLYDLAHNNAKFEEHGGRRVLVHRKGATRAFGPGHPEVPEAYRRVGQPVLVPGDMGRYSYVLAGTEKAMAVSFGSSCHGAGRKMSRHQAKKVARERNLVKELAERGILVRAATRATVDEEMPEAYKDVSLVVEAVEGAGIGKKVARLRPLIVVKG
>NZ_AP017920.1|WP_096411241.1|1168443_1169907_+|phosphodiester-glycosidase-family-protein
MRRFALLLFFGLALGQTLLPVEQLGLTFREEGGAWVYQGSGKRFVYVPGVGWSEPLGAELPPPQEDLFPLEALKALGYFRVAEAGVRFGERPSGLRVVLDLPAPYPAEPREERGKAGATLYLPYLAPDLLKAPWPKGLKARVRLLPEATELALRAEEGHLYYRLFPLEDPPRLVLDLYLLAPEVEEVLSPGVRYREVYGFAPEPLRLYLVEAERGRLLPVGTPGKRALPKDLAPGALAVLNGGYFDPKTGTPIGLWVQDGVTLSYPYGRVALLWDGFAFFLGFPQFVAEAVGPDGSRVRVGVNASRARYTAHTVPGTVGREGEEVALVREDRVVDLLPAPAELPPGHWALTFPRDAPPFPLEVGGRLALYGTLTPPFRYALEGGPLLLKEGRYAYDPAKENFKDPRPLQAVAPQAAVAWTKEGKLWLLVSEPTTPGALARALLSLGAWNALRMDGGGSAQLWVKGQLRSPYTGSPRPVVNALALYLE
>NZ_AP017920.1|WP_096411242.1|1169959_1171486_+|DUF4338-domain-containing-protein
MPLDITLESWLWDAACAIRGPVGAPKFKDSILPLAFLERLSDVLEEELYRLAEECSNREVALSLVEEERKEGAIAQGRGLVRFYIPEEARWTNIRKQDKGLGQYLTNAVRKKKLSRMVMSVEAELRKRVIEHLRELGFKVENGELALEGNSDKHFLRRLHDAVRRLALYQMQGWVENLWPRLRPYFADGRDINPEAIRPVLVEATTPWQRELFRLARLTWSLPYSKGYGRRLRFLILDEGNRNPEGQPYLMGILALQSPPLSFPPRDRRFQYPPGRKTELVNQTMDIHTLGALPPYSYLLGGKLVALAAASNEVREAYRRKYEGRRTEIEGRVLPAHLVALTTTSAFGRSSLYNRLKYNGEPIAISIGYTEGYGTFHLEPLYPLFREYLEAQGISTRGGYNVGPRIKWQTCVRALERLGFSGALLKHTIRREVFLFPLIHNLDDYMEGRTDEPEYKDLPFADLGAYWRERWLLPRVARVDGWYKWEAEQLLESLLVRNEATGVRSDER
>NZ_AP017920.1|WP_041444412.1|1171475_1172621_+|DNA-double-strand-break-repair-nuclease-NurA
MNGENERPFADLPAALVEEMLIRTEPLSQRMQADFERLRAERRQRRQALEESGLLRREGELPAVSVPTTCGVDGAYALERLVATDLVAAAAVAVEGLTPPSETRFWPEPRHRVYVDAEAHEEETGTLARAVMMGMELELASQAPHDVVFLDGSLTTPLIYFNQALNRAIQTPDLRLTAHLRDHTLNYLKAYHTVLQARRTDRAWVAVPKYSVRREIGERFKWEMDDRAMLTNLLEPGEFTDPQRLESPRQPWHINLDLLPEEIRGQAEKLRDEIIHLLEEVRVVYYRPWAWLPALRLEMSRTVAENRARLATVIQALRFQCSAPGMLEPYPLYLADRMVKHLGRAVPALRQVTSQRLAVTYGGDIGDVFLNLHGYRTEGGR
>NZ_AP017920.1|WP_096411243.1|1172644_1174486_+|ATP-binding-protein
MLEQAVDIDRLIDEAERIGVVGSPSSTSELALDVLASAADKKLVGEFGLFRFRQDGKNHYALGQITEVKLRNVWHEDPTMRSLIRQRGRVDAVSERQDTHQGEMTVSAVFARDGSNYRPSILGTVPATGTPICLVDDRVLDALLAPYRNQLFYLGRVYGSTPKLPLWFKHFGHGPDGAGEAYHLGIFGKTGSGKSVLAKMILLAYARYPQMAMLVLDPQGEFAKDLRGEPTGEFRLPMNDVLRRLGKPTKVLSVRDLVLDRWELFAQILYESPFFEQLSVPKGENRELACQTLTDRLRRAKVHLRDLHTRDAFDKAWQLLGEEQIQKVFYRSESSRARFQSMYEEADPDQFYNAYWRPVTWLFREDRKDAQKVDSLLYQLLVPKEKEGTRPLMVIDLSEEQARKASGDVSSLPLFGGNADVQDQPTMLWNETIQALVVKRLLEGIRSAAEAAYKESRSLNTLVLMDEAHRLAPREDPENQEKKAIRELLIDAARTTRKYGVGWMFISQTLSSLHRGIVEQLRIFFFGFGLGMGQEFRALSELVGGRSKALDLYQLFRDPHSAFDVASREYSFMTIGPVSPLSFSGTPLFFNVFNRVEEFLEANFGKHNLGRSS
>NZ_AP017920.1|WP_157745800.1|1174824_1175151_-|winged-helix-turn-helix-domain-containing-protein
MERGIEGLADSKPPGARPRSTSAMSAFLRERLQGEEAWTAPQLLKALEKRFFVTFHPGTVRRKLLEMGYWWKRMRYVPTGKPREVEGFRAALGDAFPPGKHLEAERGG
>NZ_AP017920.1|WP_096413040.1|1175388_1175697_+|M48-family-metallopeptidase
MHGHLWEGAAVSREILLAEVRAWAQRIGVEDRLRKVQTRPMQRKWASVSSRGRLTLNEELLTQPAEVRWAVIVHELVHLKLRNGAHSELFRALVQAYLEGTL
>NZ_AP017920.1|WP_157745802.1|1175726_1176650_+|hypothetical-protein
MGPGFHRLYAARLAWRYRLLLALALALLGVFHPLLALLSPLGLLLPARLWEGRALKEISRVSLAYATALAYGEERLWAEAGKVPARLPPFPWGLLLAYVLALLLVLGLHLTRPVPFSLPGPAGVERVAPPSREGQAQDGAAGEKEAQGEANGEGQAGPSQGKEQGPPQRPPGKAPPGRGRKPRPARGGLLCPGPPPDRKPGGRGRACGSPPREDGGGRETPPPQASRRGPSAGGAPEEKEGALPPTQAQGPEVGLLGEGEEGEKAALPSPWPAGRPPEAVRRGVEVYLEKTPLPPEARELLRRYFAP

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Crispr_ID: NZ_AP017920_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017920_5

1686869-1688051

Orphan

III-A

Consensus_repeat	Method
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	PILER-CR
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CRISPRCasFinder
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACNN	CRT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CRISPRCasFinder

15 spacers

The CRISPR arrays of NZ_AP017920_5

>merge|NZ_AP017920|5|1686869-1688051|PILER-CR,CRISPRCasFinder,CRT,CRISPRCasFinder
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTCCTTGCCCTCGTAGGTCTCCGTCTGGAGCCTCCCTTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTAGGCCCCACCCTAGGGGGTGCCCTAGGCACCCCTTCAGGTAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTGAAAGCACAGTTGTAGTTGGCTTGCCCGTTCTCCTGGAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTGGAGGGGCCTGGCCCGGAACAGGAGCTCTTCGAGCTCTTGCCGGGTTGCAAGAGCTTGAGCCCGTAAGGGATTGCGACGGGACGTAGTACGTGGAGACGGCTCCCTCTTCCTCCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACGCTGACCGCAATAACGCACATCGCTCACCCCCTAATCCAGTAGAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACGGGCCCCGTAATCTGTATCGTCAGGCACCCCGAAGTGCACATGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTTATCCCGCACGACCCCCTGATGCACCCAGAACTTCCGCTTTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCTCGGCGAGGTGACCGGAGAAGCTAAGGAGCAAGTCCTTGAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCCGGTCATAGACCCGGGTGGGGACGGTGGCAATGACAACCGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTCCTTGGCGTGGCGGTAGGAGGCGGGGAGGGGGAAGAACCTGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCGCCCTATGCCTCTACTCCTCCTCCGCCTCTTCCTCCTCAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTCGGTGATGAGGACGCTTCCTTCGCGACTCCTGAACTTAGCCAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACACGGGTTTGACAGCCTTGATGATCTTAGCTTTCATCTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTCGCCGTACTCCCGGGTGACGAAGACGCGGTACTCCTGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATCGCGAC

>NZ_AP017920|5|5|1686869-1688051|PILER-CR
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCCTTGCCCTCGTAGGTCTCCGTCTGGAGCCTCCCTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TAGGCCCCACCCTAGGGGGTGCCCTAGGCACCCCTTCAGGTA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGAAAGCACAGTTGTAGTTGGCTTGCCCGTTCTCCTGGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGGAGGGGCCTGGCCCGGAACAGGAGCTCTTCGAGCTCTTGCCGG
GTTGCAAGAGCTTGAGCCCGTAAGGGATTGCGACGG	GACGTAGTACGTGGAGACGGCTCCCTCTTCCTCCGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACGCTGACCGCAATAACGC	ACATCGCTCACCCCCTAATCCAGTAGAGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACGGGCCCCGTAATCTGTA	TCGTCAGGCACCCCGAAGTGCACATGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACTTATCCCGCACGACCCC	CTGATGCACCCAGAACTTCCGCTTTGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACCTCGGCGAGGTGACCGG	AGAAGCTAAGGAGCAAGTCCTTGAGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACCCGGTCATAGACCCGGG	TGGGGACGGTGGCAATGACAACCGGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACTCCTTGGCGTGGCGGTA	GGAGGCGGGGAGGGGGAAGAACCTGGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACCGCCCTATGCCTCTACT	CCTCCTCCGCCTCTTCCTCCTCAGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACTCGGTGATGAGGACGCT	TCCTTCGCGACTCCTGAACTTAGCCAGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACACGGGTTTGACAGCCTT	GATGATCTTAGCTTTCATCTGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATTGCGACTCGCCGTACTCCCGGGT	GACGAAGACGCGGTACTCCTGGTTGCAAGAGCTTGAGC
CCCGTAAGGGGATCGCGAC

>NZ_AP017920|5|5|1686869-1687131|CRISPRCasFinder
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCCTTGCCCTCGTAGGTCTCCGTCTGGAGCCTCCCTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TAGGCCCCACCCTAGGGGGTGCCCTAGGCACCCCTTCAGGTA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGAAAGCACAGTTGTAGTTGGCTTGCCCGTTCTCCTGGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTGGAGGGGCCTGGCCCGGAACAGGAGCTCTTCGAGCTCTTGCCGGGTTGCAAGAGCTTGAGCCCGTAAGGGATTGCGACGGGACGTAGTACGTGGAGACGGCTCCCTCTTCCTCCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GCTGACCGCAATAACGCACATCGCTCACCCCCTAATCCAGTAGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GGGCCCCGTAATCTGTATCGTCAGGCACCCCGAAGTGCACAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTATCCCGCACGACCCCCTGATGCACCCAGAACTTCCGCTTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CTCGGCGAGGTGACCGGAGAAGCTAAGGAGCAAGTCCTTGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGGTCATAGACCCGGGTGGGGACGGTGGCAATGACAACCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCCTTGGCGTGGCGGTAGGAGGCGGGGAGGGGGAAGAACCTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CGCCCTATGCCTCTACTCCTCCTCCGCCTCTTCCTCCTCA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCGGTGATGAGGACGCTTCCTTCGCGACTCCTGAACTTAGCCA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACGGGTTTGACAGCCTTGATGATCTTAGCTTTCATCT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCGCCGTACTCCCGGGTGACGAAGACGCGGTACTCCTG


>NZ_AP017920|5|5|1686869-1688051|CRT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCCTTGCCCTCGTAGGTCTCCGTCTGGAGCCTCCCTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TAGGCCCCACCCTAGGGGGTGCCCTAGGCACCCCTTCAGGTA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGAAAGCACAGTTGTAGTTGGCTTGCCCGTTCTCCTGGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGGAGGGGCCTGGCCCGGAACAGGAGCTCTTCGAGCTCTTGCCGG
GTTGCAAGAGCTTGAGCCCGTAAGGGATTGCGACGG	GACGTAGTACGTGGAGACGGCTCCCTCTTCCTCC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GCTGACCGCAATAACGCACATCGCTCACCCCCTAATCCAGTAGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GGGCCCCGTAATCTGTATCGTCAGGCACCCCGAAGTGCACAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTATCCCGCACGACCCCCTGATGCACCCAGAACTTCCGCTTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CTCGGCGAGGTGACCGGAGAAGCTAAGGAGCAAGTCCTTGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGGTCATAGACCCGGGTGGGGACGGTGGCAATGACAACCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCCTTGGCGTGGCGGTAGGAGGCGGGGAGGGGGAAGAACCTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CGCCCTATGCCTCTACTCCTCCTCCGCCTCTTCCTCCTCA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCGGTGATGAGGACGCTTCCTTCGCGACTCCTGAACTTAGCCA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACGGGTTTGACAGCCTTGATGATCTTAGCTTTCATCT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCGCCGTACTCCCGGGTGACGAAGACGCGGTACTCCTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATCGCGAC

>NZ_AP017920|5|6|1687246-1688051|CRISPRCasFinder
	TCCTTGCCCTCGTAGGTCTCCGTCTGGAGCCTCCCTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TAGGCCCCACCCTAGGGGGTGCCCTAGGCACCCCTTCAGGTA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGAAAGCACAGTTGTAGTTGGCTTGCCCGTTCTCCTGGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTGGAGGGGCCTGGCCCGGAACAGGAGCTCTTCGAGCTCTTGCCGGGTTGCAAGAGCTTGAGCCCGTAAGGGATTGCGACGGGACGTAGTACGTGGAGACGGCTCCCTCTTCCTCCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GCTGACCGCAATAACGCACATCGCTCACCCCCTAATCCAGTAGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GGGCCCCGTAATCTGTATCGTCAGGCACCCCGAAGTGCACAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTATCCCGCACGACCCCCTGATGCACCCAGAACTTCCGCTTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CTCGGCGAGGTGACCGGAGAAGCTAAGGAGCAAGTCCTTGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGGTCATAGACCCGGGTGGGGACGGTGGCAATGACAACCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCCTTGGCGTGGCGGTAGGAGGCGGGGAGGGGGAAGAACCTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CGCCCTATGCCTCTACTCCTCCTCCGCCTCTTCCTCCTCA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCGGTGATGAGGACGCTTCCTTCGCGACTCCTGAACTTAGCCA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACGGGTTTGACAGCCTTGATGATCTTAGCTTTCATCT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TCGCCGTACTCCCGGGTGACGAAGACGCGGTACTCCTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017920.1\|WP_096411845.1\|1678231_1678645_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|161843
NZ_AP017920.1\|WP_096411848.1\|1679294_1679690_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184875
NZ_AP017920.1\|WP_096411858.1\|1683206_1684484_+\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NZ_AP017920.1\|WP_096411881.1\|1693476_1694337_-\|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl\|CDD\|163676
NZ_AP017920.1\|WP_096411892.1\|1704337_1705021_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NZ_AP017920.1\|WP_096411835.1\|1673843_1674506_+\|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	unknown	unknown	gnl\|CDD\|350159
NZ_AP017920.1\|WP_096413097.1\|1697228_1697504_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017920.1\|WP_096411871.1\|1690921_1691551_-\|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|308985
NZ_AP017920.1\|WP_096411867.1\|1689901_1690972_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|211340
NZ_AP017920.1\|WP_096411884.1\|1694348_1695935_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223571
NZ_AP017920.1\|WP_096411853.1\|1680268_1681792_-\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NZ_AP017920.1\|WP_096411865.1\|1688174_1689887_+\|M3-family-oligoendopeptidase	unknown	unknown	gnl\|CDD\|274069
NZ_AP017920.1\|WP_096411862.1\|1684484_1686284_-\|RNB-domain-containing-ribonuclease	unknown	unknown	gnl\|CDD\|223631
NZ_AP017920.1\|WP_096411841.1\|1677295_1678258_+\|membrane-dipeptidase	unknown	unknown	gnl\|CDD\|238626
NZ_AP017920.1\|WP_096411876.1\|1692074_1692470_+\|DUF3197-domain-containing-protein	unknown	unknown	gnl\|CDD\|371529
NZ_AP017920.1\|WP_096411850.1\|1679686_1680127_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017920.1\|WP_096411888.1\|1703627_1704341_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319852
NZ_AP017920.1\|WP_096411838.1\|1674520_1675444_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_AP017920.1\|WP_172844675.1\|1678666_1679344_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_AP017920.1\|WP_096411874.1\|1691569_1692058_+\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981

Protein	Function_ID	Function_description	E-value
NZ_AP017920.1\|WP_096411845.1\|1678231_1678645_-\|PaaI-family-thioesterase	gnl\|CDD\|161843	TIGR00369, Putative_esterase, uncharacterized domain 1. Most proteins containing this domain consist almost entirely of a single copy of this domain. A protein from C. elegans consists of two tandem copies of the domain. The domain is also found as the N-terminal region of an apparent initiation factor eIF-2B alpha subunit of Aquifex aeolicus. The function of the domain is unknown.	3.55922e-38
NZ_AP017920.1\|WP_096411848.1\|1679294_1679690_+\|hypothetical-protein	gnl\|CDD\|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	0.00207947
NZ_AP017920.1\|WP_096411858.1\|1683206_1684484_+\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NZ_AP017920.1\|WP_096411881.1\|1693476_1694337_-\|hydroxymethylglutaryl-CoA-lyase	gnl\|CDD\|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	1.19861e-116
NZ_AP017920.1\|WP_096411892.1\|1704337_1705021_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	7.7708e-147
NZ_AP017920.1\|WP_096411835.1\|1673843_1674506_+\|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	gnl\|CDD\|350159	cd09008, MTAN, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs): bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	1.72387e-65
NZ_AP017920.1\|WP_096411867.1\|1689901_1690972_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|211340	cd02575, PseudoU_synth_EcTruD, Pseudouridine synthase, similar to Escherichia coli TruD. This group consists of bacterial pseudouridine synthases similar to Escherichia coli TruD. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). E. coli TruD makes the highly phylogenetically conserved psi13 in tRNAs.	1.02028e-99
NZ_AP017920.1\|WP_096411884.1\|1694348_1695935_-\|AAA-family-ATPase	gnl\|CDD\|223571	COG0497, RecN, ATPase involved in DNA repair [DNA replication, recombination, and repair].	3.67158e-145
NZ_AP017920.1\|WP_096411853.1\|1680268_1681792_-\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	2.74617e-65
NZ_AP017920.1\|WP_096411865.1\|1688174_1689887_+\|M3-family-oligoendopeptidase	gnl\|CDD\|274069	TIGR02290, oligoendopeptidase_F, oligoendopeptidase, pepF/M3 family. The M3 family of metallopeptidases contains several distinct clades. Oligoendopeptidase F as characterized in Lactococcus, the functionally equivalent oligoendopeptidase B of group B Streptococcus, and closely related sequences are described by TIGR00181. The present family is quite similar but forms a distinct clade, and a number of species have one member of each. A greater sequence difference separates members of TIGR02289, probable oligoendopeptidases of the M3 family that probably should not be designated PepF.	0
NZ_AP017920.1\|WP_096411862.1\|1684484_1686284_-\|RNB-domain-containing-ribonuclease	gnl\|CDD\|223631	COG0557, VacB, Exoribonuclease R [Transcription].	2.66436e-74
NZ_AP017920.1\|WP_096411841.1\|1677295_1678258_+\|membrane-dipeptidase	gnl\|CDD\|238626	cd01301, rDP_like, renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics. Although the biological function of the enzyme is still unknown, it has been suggested to play a role in the renal glutathione metabolism.	1.22373e-52
NZ_AP017920.1\|WP_096411876.1\|1692074_1692470_+\|DUF3197-domain-containing-protein	gnl\|CDD\|371529	pfam11432, DUF3197, Protein of unknown function (DUF3197). This bacterial family of proteins has no known function.	1.48646e-51
NZ_AP017920.1\|WP_096411871.1\|1690921_1691551_-\|YkgJ-family-cysteine-cluster-protein	gnl\|CDD\|308985	pfam03692, CxxCxxCC, Putative zinc- or iron-chelating domain. This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.	0.00188071
NZ_AP017920.1\|WP_096411888.1\|1703627_1704341_-\|HAD-family-hydrolase	gnl\|CDD\|319852	cd16415, HAD_dREG-2_like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to uncharacterized Drosophila melanogaster rhythmically expressed gene 2 protein and human haloacid dehalogenase-like hydrolase domain-containing protein 3. The haloacid dehalogenase-like (HAD) hydrolases are a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members include 2-L-haloalkanoic acid dehalogenase (C-Cl bond hydrolysis), azetidine hydrolase (C-N bond hydrolysis); phosphonoacetaldehyde hydrolase (C-P bond hydrolysis), phosphoserine phosphatase and phosphomannomutase (CO-P bond hydrolysis), P-type ATPases (PO-P bond hydrolysis) and many others. Members are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.49792e-32
NZ_AP017920.1\|WP_096411838.1\|1674520_1675444_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	5.55651e-154
NZ_AP017920.1\|WP_172844675.1\|1678666_1679344_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.54228e-06
NZ_AP017920.1\|WP_096411874.1\|1691569_1692058_+\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	8.8455e-08

>NZ_AP017920.1|WP_096411862.1|1684484_1686284_-|RNB-domain-containing-ribonuclease
MLRGVAALVVYKGKPALAEEKGGRLELTLEGGAKQKVRPKDVLFLHPGPASLDLKVPEGEEEAAWELLEGQTVSLRELAELVYGAYTPEAAYGAYLLAQRGERFVLEGEGVRARTREELLALKEAERKRVERERAFQEALKRLREGSPAPEDRPLLAEVEALARGERKESPVLRALGLPETPEAAHAFLLRLGLWQRENPHPRRLGLPLQPPDLPVPPLPEEDRVDLTHLPAFAIDDEGSQDPDDAVFAERVKGGFRLFVHVADVAALVPPKSPLDEEALRRGANLYLPEGTVPMLPPAVTEALGLGLREVSPALTFELWVSEEGELLEERVYPSWVRVKRLTYREALGVEALRPLEALAEAFRARRLAAGALEIALPEVKVRVEGEEVRITPLPPYPSRAWVREAMLLAGYAAAHLAVREGLPFPFAAQEAPSRRVEGEGLAAMWEQRKAMKRAQLKAVPAPHKGLGLPLYAQVTSPLRRYLDLVAHQQLRAWLKGERPLSQSEVLERVGAAEAVADLVREAERKSKLHWTLLYLQERGYEGPGVLVERRGGQGVFLLPELGLSAQVALSQALPLNAEARLRFLEADLPGLEARFALV
>NZ_AP017920.1|WP_096411858.1|1683206_1684484_+|NADP-dependent-isocitrate-dehydrogenase
MAYTHIRIPEEGEKITIKDGVLQVPDRPLIGFIEGDGTGPDIWRAAKPVLDAAVEKAYGGRRRIVWVEIYAGEKANQVYGEPVWLPEETLEFIREHLVAIKGPLTTPVGGGIRSINVALRQELDLYACVRPVRWFRGVPSPVKHPELVNMVIFRENTEDIYAGIEWPAGSEEVRKVLDFLKREFPKAYAKIRFPETSGLGIKPVSKEGTERLVEAAIEYAIKEDLPSVTLVHKGNIMKFTEGAFREWGYALAREKYGAVPLDGGPWHVMKNPRTGREIVIKDVIADNFLQQVLLRPDEYSVIATLNLNGDYISDALAAQVGGIGIAPGANINYRTGHAVFEATHGTAPKYAGQDKVNPSSVILSGEMMLRYLGWNEAADLILQAMERTIAKGLVTYDFHRLLQAEGKPATLLKTSEFGRALIEHM
>NZ_AP017920.1|WP_096411853.1|1680268_1681792_-|tRNA-lysidine(34)-synthetase-TilS
MDVPAFRERLLRLAPKDPLVLAVSGGGDSVALALLVKEAGRQAVVAHLDHGLRPESPLDQAFVRALAERLGFPFFTERVEVARIAQARGENLEAVAREVRYAFLHRVAREVGARAILTAHTLDDQAETVLLQLLQGTARATGIREREGIVVRPLLAHTREELRAYLRARGEAWREDPTNQDPALDRNFLRLFVLPLLEERFPAAKRALARFAEARAEEEGVLERQAEARLLPDPRFFVPAFRAAPLLEAPLAVRRRALRRLLEKLGLRPEARLVLLLEEALRGRPQTLPGGVLARRKGGTLFLLPPRPRLPLPPGFRRPAPGDYLERPSGRKRLVDFLAEKGVPRELKPLWPVRAEGSRVVEVLGLYPPPPEEAHMAEALAEAALAFREGEVPVGAVLVLPGRVLRAHNRVEGLRDPTAHAEMLLLREAGPEARGGRLYVTLEPCLMCHHALAQAGVEVVYGAENLKEGALTRFGLPTRARGGVRERECAKLLRDFFARLREGCRSG
>NZ_AP017920.1|WP_096411850.1|1679686_1680127_+|hypothetical-protein
MRKLLATAVLLLGLASAQFSVENLKPSFAFVGGTQGFGLELSWHCLLFQLPVGEVRPALDLAYTVAGDFNGAFLFRYLYPVAEGFKAGAGLGVAVTGLNFSNTSLYFRADAEYDLAQALNVPAFVGADLGLAGGKFAAQLKVGYRF
>NZ_AP017920.1|WP_096411848.1|1679294_1679690_+|hypothetical-protein
MRRTGYLHLYGLNLVFDRVGKGPPVLLVAEEASRWPEALPEGYTFYLLDLPGYGRTEGPRMAPEELAHFVAGFAVMMNLGSPWVLLRGLGLALGPHLEALGLRALPAEGVEITEVLSSKLSYGSIDPGGNL
>NZ_AP017920.1|WP_172844675.1|1678666_1679344_+|alpha/beta-hydrolase
MGEIRLFPGLLAPPAGLDFLLDLPSEEGLHLVAFAEGALDALKAAFREGARSLVLLSPVLFRDALLGARLGALRFGLERGGVEGFARVGRALFFGALSAGSEEVYEAWKEGLSEAGLWRWLGRLEALTDERRWLRGTEARVLVVQGALDAFTPPLHGAKVADFAKGEALRFVVDEAGHLVPWEAQEEVRDLVADFLLGEGFRPLPGGSPYEAHGLPPPLRPEPGL
>NZ_AP017920.1|WP_096411845.1|1678231_1678645_-|PaaI-family-thioesterase
MEVKAFLERETLDQTLGVRYLKAEKDEVVAELAVTPKVHQPFGFLHGGATVALAESVASVGGFLNCPPGHAAFGLEINCNHLRKKREGTIRAVGKPLHVGRTTQVWEVKVYDEEGRLVAASRCTLAVVPLEPAKEPA
>NZ_AP017920.1|WP_096411841.1|1677295_1678258_+|membrane-dipeptidase
MPPFLVDAHLDLAWNARALGRDLTLSLEALRAQDPHPDTPLVTLPSLKEAGVALAFATLFADPREGAREDWEEEVYAQLALYEAWERGGLVRVLRERADLLAHLERFPQDGVLGLVLLLEGAHALEAPEDLRPLRERGLRLLSLTWATGNAYAGGNAEPGPLTAKGQALLQEMAALGVALDLSHLAEEAAWRALEAYRGPVCATHANCRALVPSERHLSDGLLRALAGREGVLGLVPFNAFLDPAWKRGMPRLPLEAFLRHKAHAEALMGGGRVGLGTDWDGGFGLEATPQGLDRHRDLCALGGEGFLGGNWLRWLLGWF
>NZ_AP017920.1|WP_096411838.1|1674520_1675444_+|ribose-phosphate-pyrophosphokinase
MEIQLFSGSAHPDLARRVAEALGVPLGKALVDRFPDGEVRVRLLESVRGEDVYLIQPTCPPVNDHLMELLLLADAARRSSAGRINAVIPYFGYARQDKQTEGREPISAKLVAGLLERVGVERVIAIDLHAPQIQGFFDIPVDHLSAVRLFARYLREKGYVENAVVVSPDAGRAEEAGRLAERLGLPLAMLAKRRLGPRETSVTYVIGDVEGKRPILVDDIVSTGGTIRRGVEALLRAGALPEVVVMATHAVLVGEARENLSHPAIQEVVFTDTVPLKDGGYTVLSTAELLAQAIRHVHTNQSVSALI
>NZ_AP017920.1|WP_096411835.1|1673843_1674506_+|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase
MTAFFAAEPEEASALREALGAGEALLAPFPLHRGEGVLVAETGVGKVAAAMAVAHVLTRFRPSESFFLGVAGALDPTLRALDLLLAEKAVQWDVDLTPFGRKPGETAFGVGFFPSDPALLARAEKAALALGLPFRRGVVATGDRFLAQREEAERLRALHGADAVEMEGAAALMVAWRFRHPMALLRVVTDGAGEGAASDFQAFLREAARRLGLLARALVE
>NZ_AP017920.1|WP_096411865.1|1688174_1689887_+|M3-family-oligoendopeptidase
MEWNLDDLYAGPADPRIEEDLKAALALAQGLDPQGLLDPKEAQDLLGRYEKALELAYRPLNYASLYFATRTQDPEAKALLDRVRNRYTEVKNRLVPLEVALRKLPEEAFQRLLDHPGLADLRHFLKRQRAYAPHTLSEREEELLNLKGLVGRSAWSQFYTEYTGRFRFRVQGKELTEMEVRALRRDPSPEVRREAHRALYGKLLAEAPTLGAVFNAVYLDYLQDLRLRGYRHPLEPVALRDEVEVKDIEALLEATEAHYPLVERYYRWKARRLGREKTPSEDLLAPLGEKPKVPFAEAKALVLEAFRRFSPELEAIAREFFEKRWIDAYPRPGKRGGAFCSGGLPSTHPYILLNHTDDLDSAHTLAHELGHGVHFYLARKQRLLNFGASTPLAETASVFAEILLDDLLLERLSGEEKALLLAERVEDAIGTLFRQVMYTFFEQRSLEARKEAALSPEAFHALWDEEQRRLYGEAVAWTELDRAAWAGIPHFVHYRFYTYSYALGYLVVLALYGRYREEGEAFVPKYLRVLEAGESRSPKEILAEAGVELGSEAFFRYGFGVLESWLEALP
>NZ_AP017920.1|WP_096411867.1|1689901_1690972_+|tRNA-pseudouridine(13)-synthase-TruD
MDLVYRPERYPFLTEDLPGVGGEIRVEPQDFQVEEVPAYLPKGEGEHLYLLLEKEGRTTREVLEFLRDEVGVPEKEIGVAGLKDKRAQTRQWFSIPRKYEDALCLLENLQGVRLLAADLHTNKLRTGHLKGNRFRVLIRRPKGGVAEAEAVLRRLAEKGVPNYYGPQRFGLGGLNPVRGYKLVKEGRGRGSPWLKRFLIGSLQSLLFNDWVALRMALGLYDRVVPGDWAKKHATGGEFLVEDPREAERALRLEISATGPLFGKKYPEAQGEARAIEDEVLARYGLKREEFRARRGARRPIRVPLAEWKVEEGPEGLWLSFFLPKGSYATSLLREVMKVEALDHLETEPASEDAEGL
>NZ_AP017920.1|WP_096411871.1|1690921_1691551_-|YkgJ-family-cysteine-cluster-protein
MEAVERAFRALDEGIADYLARKGIRPSCGPGCFACCYGWVTASRLEAQALLPHLTEAQKARVLEEGPRRLALLARGKDDPGFPRRFFLSRSPCPLLEEGLCGVYAHRPLACRGVLTDEDPAYCDPENPHPAPKPHHGPGHFLRVPHRMARRRMEELWEEERARTGFLVLGELSGLLYLLLTGLPEDREGVEARLKALGVLGGRFGFQVV
>NZ_AP017920.1|WP_096411874.1|1691569_1692058_+|DinB-family-protein
MPAPFLEPLEPGVSPAVSAWIKGLKEVALHLDGWAFDLPEEPFWRRPKEGANPIGGLVRHITGSSLRLAHYALGVELPEWARKGREWELLGEPEPKEAVEARFREAWAVLLAAFRRVEEAALAEVVRVGHLGAEAPRAHVLHHLVEHAQHHAGQVIYARKLL
>NZ_AP017920.1|WP_096411876.1|1692074_1692470_+|DUF3197-domain-containing-protein
MVRVGMRAAPRVSLEALKAALGGLKLSEAKVYLITDWQDKRDQARYALLLHTGKKDLLVPDAFGPAFPGGEEALSELVGLLLAQGARKFYEAVVSPGEMTALLDLPPEELLKRVMAIANPTDPGIYLKRAA
>NZ_AP017920.1|WP_096411881.1|1693476_1694337_-|hydroxymethylglutaryl-CoA-lyase
MKARVRWVECPRDAWQGFSRFIPTEEKVAFLNKLLEAGFTHLDLTSFVSPKWVPQMQDAEEVLKALPPPNGRTYLAIVANEKGLERALATPNLTHVGYPFSLSETFQRRNTNRSIEASWPLVAAMVERTRGRLGLVVYLSMAFGNPYGDPWSVEAVLQALARLKEMGVREIALADTYGVAEPERIHEVLKAAVARFGPEGLGAHLHARPEGALAKVEAVLAAGVTWLEGALAGVGGCPFAGDELVGNLPTEVVLPHLEKRGLATGVDPSRLPLLAEEAARLKGLYA
>NZ_AP017920.1|WP_096411884.1|1694348_1695935_-|AAA-family-ATPase
MGGMLRRLEVQNLAVIREAALDFAPGLNVLTGETGAGKSLLVDALALLLGGRAEGLIGPYGESLLVTAFFEGSPGEAVLSRRVGARSTPRVDGEVVTLKELQAEAERRLSLHAQHTALALLSPRRQREALDALLPEGLLAAYQEAYARREALLKEKAALEESLRARAEREDLLRYQIREIEEARVRPGEEEELLALAERLRHLETIRERLARALALLTEREAQDLLALAAKEVRAAARHDPALEALAEELSGAAEAVRAVGRELEDHLEGLDLDPEALDRVEARLSLLERLKRKYGPTLADVLAHAQKAREELARMEGGEERLSEVERLLKALHEEVKARGQALRRAREEAARRLTEGMMRELPALGLAGARFAVVLEPLPEPGPQGLEAVAFRVAPNPNLPPAPLEALSGGELSRVALALALLTGAEAPTVVFDEVDAGVGGETAWRLAERLKRLAERRQVLVVTHLPQVAAVAQRHFRVTKTPEGVRVEPLEGEARVQEIARLLSGAYTQAALAHARELLEAQGAL
>NZ_AP017920.1|WP_096413097.1|1697228_1697504_+|hypothetical-protein
MKGNAFTILKWGLLLTLVVLLLTILLINFTTSRDLPELVRVQVERYAVCSYWFFGWHLASTGAFAFTFLLVGFLGGLALGFFLRGNAPRRA
>NZ_AP017920.1|WP_096411888.1|1703627_1704341_-|HAD-family-hydrolase
MKPKAITFDFWGTLFTEGEAFLEKVMPARYEILLDALSEAGHPAEEAEVREAYRQAALAFEEAWKAGEHMPVYERVARIFALLGAPHDPGLIALTARRLEESSLLAPLKPLPGVEVLKDLAKKYPLAIVSDTGMTPGRLLREHLKRQGLDVFQAFSFSDETGFVKPKPEAFRVALEALGVAPEEALHVGDLPQTDIKGAFGTGYPWAVQYVGLREVNGEVKPTAKVKDHRELLSLLT
>NZ_AP017920.1|WP_096411892.1|1704337_1705021_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MRWAIVRFPGANCDEDARFALKKAGLRAEFVWHTERDLRGFDGVFLPGGFSYGDYLRAGALAAKSPVMEAVRRFAEEGRYVVGVCNGFQILTEAGLLPGALLANLNLHFTCKEVGVRVERNDLPFTRLYPRGQVLRLPIAHGEGRYYADPETLARLEGEGLVVFRYAPLKGEADYNPNGSLNDIAGITNERGNVLGMMPHPERAVDEVLGNTDGLPFFLGLVKEVAR

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Crispr_ID: NZ_AP017920_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017920_6

2090460-2092241

TypeIII

III-A

Consensus_repeat	Method
GTCGCAATCCCCTTACGGGGCTCAAGCTCTTGCAAC	PILER-CR
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CRISPRCasFinder
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CRT

23 spacers

csx1,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cas10,cas2,csm2gr11,csm3gr7,csm5gr7

The CRISPR arrays of NZ_AP017920_6

>merge|NZ_AP017920|6|2090460-2092241|PILER-CR,CRISPRCasFinder,CRT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACGGTGGCGGTGAAGCCGAGCAGCCGCTTCCCGTCCTCGATGGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACACGATCTCTTCAGCGGGCACTTTTTCGGCCCAAGCGGTTATGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCCCCCTCCACAAGAGGCGGGGAGATTGGGCGTCCAACCTCCCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACGTAATGGCGCGCGCACGCCGTAAGAGCATGGGCCCATACTTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTTGCCGTAGCGCTTCCCCGTAGCGGGGTCCACGTAACCGAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACAGATAGGGTCAAGCCCCCATTCTCCTGTATGACCTTAGTCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACGCCTCAGCGGGCCGGGGTTCTCACAGGATGGGAGTTTTTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACAAGCTGGGCGCTTATCCCGATGTGGGCCTCATCAAATGTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCGGCCCTCGTGGGGCCGCCAGTTGCACAGGAGGTGGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACAAGACCTCACGCCACAGCTCCCACGCCTTCCCGTCCGCTTGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCAGACCTCCTCCGCTATCCAGAGCTCCTCGCCCCCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCCGATATACTTGCGCAACCCCTGCCCCACTCCCTGGCCCAGGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTTTGGTTCTTTGTTTGGTTCTTTTTTTGGTTCGTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCCGCCGCTTCCCTCTCTGTTACCTTTTGCCCGTCAATGTAGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACACATGTGTGCGTTGCGATGACGAGGTGGAGAGGGACGATGCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCACCGCCAGCGCTTGCCGTCAAAGGTCCAAACCGATTCTTCGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTTCTCCTTGAGGCTTGTAAACCTGCGGGCTATCTTGGCGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCCGCATGGGCCCACAGCTTACGCCTAACGCCCCCATGGCGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACCCTCCCACATACGCTCAAAGACTTCGCGTGCAAACTTGTTGCAGGAGCTTGAGCCCCGTAAGGGGATTGCGACCCCGGAAATCGCCCCGGTGGTGGTTCGCCTTAACCACATGGGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACAGCCTTTTCTGCGCTTCTACCAGAGCAGAGAGGAGTTCCGCGAGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACAGCAAGTTCGGCTTCCGTGAGGCCGCGCTTACGCCGCAGTGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGACTGGACGCTCTGGATGCCGCCATCCTCGCCGCCTATGACGCCCATGTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCCGC

>NZ_AP017920|6|6|2090460-2092161|PILER-CR
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GGTGGCGGTGAAGCCGAGCAGCCGCTTCCCGTCCTCGATGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACGATCTCTTCAGCGGGCACTTTTTCGGCCCAAGCGGTTAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCCCCTCCACAAGAGGCGGGGAGATTGGGCGTCCAACCTCCC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GTAATGGCGCGCGCACGCCGTAAGAGCATGGGCCCATACTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTGCCGTAGCGCTTCCCCGTAGCGGGGTCCACGTAACCGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGATAGGGTCAAGCCCCCATTCTCCTGTATGACCTTAGTC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GCCTCAGCGGGCCGGGGTTCTCACAGGATGGGAGTTTTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AAGCTGGGCGCTTATCCCGATGTGGGCCTCATCAAATGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CGGCCCTCGTGGGGCCGCCAGTTGCACAGGAGGTGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AAGACCTCACGCCACAGCTCCCACGCCTTCCCGTCCGCTTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CAGACCTCCTCCGCTATCCAGAGCTCCTCGCCCCC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGATATACTTGCGCAACCCCTGCCCCACTCCCTGGCCCAGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTTGGTTCTTTGTTTGGTTCTTTTTTTGGTTCGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGCCGCTTCCCTCTCTGTTACCTTTTGCCCGTCAATGTAG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACATGTGTGCGTTGCGATGACGAGGTGGAGAGGGACGATGC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CACCGCCAGCGCTTGCCGTCAAAGGTCCAAACCGATTCTTCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTCTCCTTGAGGCTTGTAAACCTGCGGGCTATCTTGGCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGCATGGGCCCACAGCTTACGCCTAACGCCCCCATGGC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCTCCCACATACGCTCAAAGACTTCGCGTGCAAACTT
GTTGCAGGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCCGGAAATCGCCCCGGTGGTGGTTCGCCTTAACCACATGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGCCTTTTCTGCGCTTCTACCAGAGCAGAGAGGAGTTCCGCGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGCAAGTTCGGCTTCCGTGAGGCCGCGCTTACGCCGCAGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC

>NZ_AP017920|6|7|2090460-2092241|CRISPRCasFinder
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GGTGGCGGTGAAGCCGAGCAGCCGCTTCCCGTCCTCGATGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACGATCTCTTCAGCGGGCACTTTTTCGGCCCAAGCGGTTAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCCCCTCCACAAGAGGCGGGGAGATTGGGCGTCCAACCTCCC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GTAATGGCGCGCGCACGCCGTAAGAGCATGGGCCCATACTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTGCCGTAGCGCTTCCCCGTAGCGGGGTCCACGTAACCGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGATAGGGTCAAGCCCCCATTCTCCTGTATGACCTTAGTC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GCCTCAGCGGGCCGGGGTTCTCACAGGATGGGAGTTTTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AAGCTGGGCGCTTATCCCGATGTGGGCCTCATCAAATGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CGGCCCTCGTGGGGCCGCCAGTTGCACAGGAGGTGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AAGACCTCACGCCACAGCTCCCACGCCTTCCCGTCCGCTTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CAGACCTCCTCCGCTATCCAGAGCTCCTCGCCCCC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGATATACTTGCGCAACCCCTGCCCCACTCCCTGGCCCAGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTTGGTTCTTTGTTTGGTTCTTTTTTTGGTTCGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGCCGCTTCCCTCTCTGTTACCTTTTGCCCGTCAATGTAG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACATGTGTGCGTTGCGATGACGAGGTGGAGAGGGACGATGC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CACCGCCAGCGCTTGCCGTCAAAGGTCCAAACCGATTCTTCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTCTCCTTGAGGCTTGTAAACCTGCGGGCTATCTTGGCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGCATGGGCCCACAGCTTACGCCTAACGCCCCCATGGC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCTCCCACATACGCTCAAAGACTTCGCGTGCAAACTT
GTTGCAGGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCCGGAAATCGCCCCGGTGGTGGTTCGCCTTAACCACATGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGCCTTTTCTGCGCTTCTACCAGAGCAGAGAGGAGTTCCGCGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGCAAGTTCGGCTTCCGTGAGGCCGCGCTTACGCCGCAGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGGACGCTCTGGATGCCGCCATCCTCGCCGCCTATGACGCCCAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCCGC

>NZ_AP017920|6|6|2090460-2092241|CRT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GGTGGCGGTGAAGCCGAGCAGCCGCTTCCCGTCCTCGATGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACGATCTCTTCAGCGGGCACTTTTTCGGCCCAAGCGGTTAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCCCCTCCACAAGAGGCGGGGAGATTGGGCGTCCAACCTCCC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GTAATGGCGCGCGCACGCCGTAAGAGCATGGGCCCATACTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTGCCGTAGCGCTTCCCCGTAGCGGGGTCCACGTAACCGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGATAGGGTCAAGCCCCCATTCTCCTGTATGACCTTAGTC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	GCCTCAGCGGGCCGGGGTTCTCACAGGATGGGAGTTTTT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AAGCTGGGCGCTTATCCCGATGTGGGCCTCATCAAATGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CGGCCCTCGTGGGGCCGCCAGTTGCACAGGAGGTGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AAGACCTCACGCCACAGCTCCCACGCCTTCCCGTCCGCTTG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CAGACCTCCTCCGCTATCCAGAGCTCCTCGCCCCC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGATATACTTGCGCAACCCCTGCCCCACTCCCTGGCCCAGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTTGGTTCTTTGTTTGGTTCTTTTTTTGGTTCGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGCCGCTTCCCTCTCTGTTACCTTTTGCCCGTCAATGTAG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	ACATGTGTGCGTTGCGATGACGAGGTGGAGAGGGACGATGC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CACCGCCAGCGCTTGCCGTCAAAGGTCCAAACCGATTCTTCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TTCTCCTTGAGGCTTGTAAACCTGCGGGCTATCTTGGCG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCGCATGGGCCCACAGCTTACGCCTAACGCCCCCATGGC
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCTCCCACATACGCTCAAAGACTTCGCGTGCAAACTT
GTTGCAGGAGCTTGAGCCCCGTAAGGGGATTGCGAC	CCCGGAAATCGCCCCGGTGGTGGTTCGCCTTAACCACATGG
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGCCTTTTCTGCGCTTCTACCAGAGCAGAGAGGAGTTCCGCGA
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	AGCAAGTTCGGCTTCCGTGAGGCCGCGCTTACGCCGCAGT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCGAC	TGGACGCTCTGGATGCCGCCATCCTCGCCGCCTATGACGCCCAT
GTTGCAAGAGCTTGAGCCCCGTAAGGGGATTGCCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017920.1\|WP_096412819.1\|2095421_2096147_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_AP017920.1\|WP_096412803.1\|2087422_2087767_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NZ_AP017920.1\|WP_096412797.1\|2085313_2086543_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|224286
NZ_AP017920.1\|WP_096412800.1\|2086558_2087419_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NZ_AP017920.1\|WP_096412785.1\|2078424_2079726_-\|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl\|CDD\|129868
NZ_AP017920.1\|WP_096412792.1\|2081951_2082362_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017920.1\|WP_096412833.1\|2101260_2101926_+\|DUF4397-domain-containing-protein	unknown	unknown	gnl\|CDD\|379570
NZ_AP017920.1\|WP_096412813.1\|2092270_2092543_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0081_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_AP017920.1\|WP_096412810.1\|2088812_2090000_-\|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|378186
NZ_AP017920.1\|WP_172844688.1\|2102670_2103939_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|378820
NZ_AP017920.1\|WP_096412817.1\|2095006_2095411_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|187778
NZ_AP017920.1\|WP_172844687.1\|2097026_2098151_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NZ_AP017920.1\|WP_096412826.1\|2098161_2099556_+\|type-III-A-CRISPR-associated-protein-Csm6	csx1	cd09747_csx1_CAS-III	gnl\|CDD\|378236
NZ_AP017920.1\|WP_096410480.1\|2080330_2081428_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_AP017920.1\|WP_096412806.1\|2087769_2088816_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|187792
NZ_AP017920.1\|WP_096412842.1\|2103853_2105257_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274272
NZ_AP017920.1\|WP_096412837.1\|2101912_2102665_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|369777
NZ_AP017920.1\|WP_096412789.1\|2079722_2080208_-\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|377284
NZ_AP017920.1\|WP_096412794.1\|2082488_2084243_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	gnl\|CDD\|187810
NZ_AP017920.1\|WP_096412829.1\|2099703_2100933_+\|YeeE/YedE-family-protein	unknown	unknown	gnl\|CDD\|377230

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_AP017920.1\|WP_096412810.1\|2088812_2090000_-\|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	3.5e-64	212.0	0.0
NZ_AP017920.1\|WP_096412803.1\|2087422_2087767_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	2.4e-32	106.6	1.8
NZ_AP017920.1\|WP_096412817.1\|2095006_2095411_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	1.7e-25	84.5	1.8
NZ_AP017920.1\|WP_172844687.1\|2097026_2098151_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	3.5e-19	63.9	0.0
NZ_AP017920.1\|WP_096412797.1\|2085313_2086543_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	1.8e-28	94.3	0.0
NZ_AP017920.1\|WP_096412800.1\|2086558_2087419_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	1.3e-84	278.8	0.0
NZ_AP017920.1\|WP_096412806.1\|2087769_2088816_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	1.1e-47	157.5	0.0
NZ_AP017920.1\|WP_096412826.1\|2098161_2099556_+\|type-III-A-CRISPR-associated-protein-Csm6	csx1	cd09747_csx1_CAS-III	2.1e-101	334.2	0.0
NZ_AP017920.1\|WP_096412819.1\|2095421_2096147_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	5.8e-80	262.8	0.0
NZ_AP017920.1\|WP_096412794.1\|2082488_2084243_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	1.8e-120	398.0	0.0
NZ_AP017920.1\|WP_096412813.1\|2092270_2092543_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0081_cas2_CAS-I:CAS-II:CAS-III	1.8e-48	157.6	0.6

Protein	Function_ID	Function_description	E-value
NZ_AP017920.1\|WP_096412819.1\|2095421_2096147_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.6096e-105
NZ_AP017920.1\|WP_096412803.1\|2087422_2087767_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	1.39748e-32
NZ_AP017920.1\|WP_096412797.1\|2085313_2086543_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.70221e-26
NZ_AP017920.1\|WP_096412800.1\|2086558_2087419_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	1.37047e-105
NZ_AP017920.1\|WP_096412785.1\|2078424_2079726_-\|TRAP-transporter-large-permease-subunit	gnl\|CDD\|129868	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit. The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive force-dependent uptake of dicarboxylates into R. capsulatus. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.17393e-92
NZ_AP017920.1\|WP_096412833.1\|2101260_2101926_+\|DUF4397-domain-containing-protein	gnl\|CDD\|379570	pfam14344, DUF4397, Domain of unknown function (DUF4397). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 120 amino acids in length.	3.24391e-32
NZ_AP017920.1\|WP_096412813.1\|2092270_2092543_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.33905e-24
NZ_AP017920.1\|WP_096412810.1\|2088812_2090000_-\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	2.03059e-71
NZ_AP017920.1\|WP_172844688.1\|2102670_2103939_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	2.79357e-08
NZ_AP017920.1\|WP_096412817.1\|2095006_2095411_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|187778	cd09647, Csm2_III-A, CRISPR/Cas system-associated protein Csm2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-A.	6.96985e-18
NZ_AP017920.1\|WP_172844687.1\|2097026_2098151_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	7.25621e-17
NZ_AP017920.1\|WP_096412826.1\|2098161_2099556_+\|type-III-A-CRISPR-associated-protein-Csm6	gnl\|CDD\|378236	pfam09670, Cas_Cas02710, CRISPR-associated protein (Cas_Cas02710). Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	5.75204e-121
NZ_AP017920.1\|WP_096410480.1\|2080330_2081428_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.11566e-09
NZ_AP017920.1\|WP_096412806.1\|2087769_2088816_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|187792	cd09661, Cmr6_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.05132e-48
NZ_AP017920.1\|WP_096412842.1\|2103853_2105257_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|274272	TIGR02733, similar_to_to_phytoene_dehydrogenase, C-3',4' desaturase CrtD. Members of this family are slr1293, a carotenoid biosynthesis protein which was shown to be the C-3',4' desaturase (CrtD) of myxoxanthophyll biosynthesis in Synechocystis sp. strain PCC 6803, and close homologs (presumed to be functionally equivalent) from other cyanobacteria, where myxoxanthophyll biosynthesis is either known or expected. This enzyme can act on neurosporene and so presumably catalyzes the first step that is committed to myxoxanthophyll. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.98636e-42
NZ_AP017920.1\|WP_096412837.1\|2101912_2102665_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.478e-17
NZ_AP017920.1\|WP_096412789.1\|2079722_2080208_-\|TRAP-transporter-small-permease	gnl\|CDD\|377284	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component. The function of the members of this family is unknown, but DctQ homologs are invariably found in the tripartite ATP-independent periplasmic transporters.	1.22973e-12
NZ_AP017920.1\|WP_096412794.1\|2082488_2084243_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	8.20988e-113
NZ_AP017920.1\|WP_096412829.1\|2099703_2100933_+\|YeeE/YedE-family-protein	gnl\|CDD\|377230	pfam04143, Sulf_transp, Sulphur transport. This is an integral membrane protein. It is predicted to have a function in the transport of sulphur-containing molecules. It contains several conserved glycines and an invariant cysteine that is probably an important functional residue.	2.13987e-52

>NZ_AP017920.1|WP_096412810.1|2088812_2090000_-|TIGR02221-family-CRISPR-associated-protein
MDSRRLILSFLGTGNYQPAKYPLDGEEYETPYTQEAILRRYQEEGYALKVLMTKEAEAKHGASLRERVEYEPVPIPSGHTEEELWEIFNTIVDNVPEGAELIMDVSHGFRSQPILALAVLHFLQATKGVKVRRILYGFYDPGTREAAFFDLTPFLTLTEWTQATRDLLEHGEGLHLRELLREIHRQSYQVDGPKAKKLSSVGEALDRVEDALDLLRVKETLESAKELLKHLGAAAQDVAQLPRSRPLGTLLDRIRERYHPLAAEDPFSPEGLKAQGEMMRLLLQTRRYAQAIALARELLVTLACLQKGWDPLEEREVAERWLSTKTKNKKSAAKDPQALPLISLWEETADLRNDVAHAAMRENPARTGRLKEAIEKVCARTQALLEAHLSRGAEG
>NZ_AP017920.1|WP_096412806.1|2087769_2088816_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MGRRSALEGVRLPQGKEPHRGLWLDKFLRSARREDTEAKRVLVREAAGVPEPGEYRAFFGRYRKALEALGAELRQARTLSRLAVGLGGEGVLETALTLQRAYGVPYIPGSALKGLASRYAHLYLEGEAWRRDLARFQRGEAQAGLFGTTEEQGLVVFWDALPLPGKWKLHPDILNPHHPDYYGSGEAPPADWDSPVPVPFLSVTGTFLLALSPAPGVSPEEAGPWLRAAWRILAWALREEGVGAKTSSGYGRMALEEPVSQGEKPPAPGPSPVLQDLLTRARALSYKEVPRFLAAQAEAILGLSAEEAEALRRALEERGFLRNLADLKRWRKEHPGLEGVLAKLGLLA
>NZ_AP017920.1|WP_096412803.1|2087422_2087767_+|type-III-B-CRISPR-module-associated-protein-Cmr5
MRTRSQVWAQKAYEKVREAARGEGRGEYRDMALKLPVLVRQAGLSQALAFVDSRGKDAHRALGNHLAQVLGYRDLRELAEAARQAELLQYLRLTREVLAVAEWFKRFAQALIEE
>NZ_AP017920.1|WP_096412800.1|2086558_2087419_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MSHAALLFLHALSPLHAGTGQGIGAIDLPIAREKATGIPYLPGSSLKGVLRDRASAWDKDTLFAVFGPDTESASEHAGAVQVGDAKLLLLPVRSLYGVFALVTSPYLLERFRREAGMAGLQVPGVPQVPDAEHALLAPGSRVLGDGGKAYLEDLDLKAREETGARAWEDWLAERTEAPVQGRLAVVHDDLMGFLLETATEVVARIRLDDETKTVAKGALWYEESLPAESLLYALVRADRSFRKGKELPPESVWGLFRGVLEEGGGVLQLGGKATVGRGLCRIVVGR
>NZ_AP017920.1|WP_096412797.1|2085313_2086543_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MRRAFQEAFSPRRKEEGGALARRDGAQVLTWERIYTLLTPLFGGGVEPREADPVSVVRATAVRGHLRFWWRALRGWRAGGSPERLWELESALFGHAGEGGASPLSVEVEVLERGQEAYPFTDVPGKKFPQANREVAHPYLAFPLRRTEQDPRNYPVRVGVAFRLRLRFPERAGGLDLREELEAALWAWETFGGIGARTRRGFGALLPQGVRPPTEGEVRERLRRYSREAGWPEGVPHLTPKSLVRVVPLSWRELAERYQAFRQARPGGNSKSPGRSYWPEPDEVRRLTGRHAPNHPPRHPVRKFPRAHFGLPIIFHFKDKGDPSDTTLQLEEAERRASPLLFRPLGEGQRPCLVAVLEGARFPGGKLILEDKRNGRTWDVDPWLTPVEARGIRVLGGEVDPVLAFVKSL
>NZ_AP017920.1|WP_096412794.1|2082488_2084243_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MEHLLAIALGPVQDFIATARRTRDLYAGSRLLSEAAAEAARALLSEVGAEGLIFPAPQDPEELKKLAEAGIPNVLLVRVPEGKDPKALGEKALEAARAHLRGRAEEVFARRREHLLWDEALAQVADLLEGYYAYLPLEGDYPRARERLMALLAARKNTRDFAPVSWGREAYKSSLDGARESVLRLPQGGADRLRVRLGLRPGEYLSGPDLLKRWWETPHGFPSTTHMAALPFWEGVRRAGLEGVLREALEELGGLVGEEARAEVHHPALWDSPFAEWDVRLLYESRLEEFPALAEDPGLLEEARARLRALWRRLSSKVRVPPGAYYALLHADGDRMGETLDGLQTPEAHRRFSNALALGFAAQVKELVEARGGGLVYSGGDDVLALLPLHRALEAARALAERFRETMAPFGREGRAPSLSVGLAVVHHLEPLQDALDLARRAEKRAKEGEPKRNALCVAYSPRSGAERMVRGRWDEDPPLTRRLLRYADLLRAGEVPSRAAYELWSLVQEVGEALPGEALAAEALRILGRKEMKGAYREELKAWLRTGEDVRRLAEELLLARPFAEALDQAGVPVESREVWDAH
>NZ_AP017920.1|WP_096412792.1|2081951_2082362_-|hypothetical-protein
MLWRRMSPEEARTRLVLLREGVGKKVRALEAQLAKKKAPLERALQEYRGVLEHLRRLEREGRYPEAVLRPALAREELRIRYAEQEMARLEEAHRQAVAQLVSRARLKAARLAALAQMEEALDRLFPLPEIKEEAHA
>NZ_AP017920.1|WP_096410480.1|2080330_2081428_-|IS4-family-transposase
MPPTTPLSQVITLWVHKVFASLRKTIRSNLALFLSTLLTTPLDPTLSDLARRTPLPTLAQSRLNRLWRFLHHPTLQDPWALTEALLPLLVPRFPKDRPLPLIVDWTFTEDGRHQALVAALPLKGRALVVAFALHPLSPFPSQNRVEEEFLHRLGRAVQDLGYTPLFLLDRGFDRVSLMRKLQGWGMGFLIRLRQNREVEPQGGKRLPLKEGYRRVVHPLREEVRLFGHGGEGVEVTLLVYPGGRDPWYLAYSGPFGGEPPYGWRMWIEEGFRDLKGQGFGLDRHRLRTGASLRGWLWLLALGMALLVLLGARLQGREWLPRLLAHPERQSLFRLGRIALAQGPPPWREAVVEELVRLLQELGGGK
>NZ_AP017920.1|WP_096412789.1|2079722_2080208_-|TRAP-transporter-small-permease
MSLWEKALGAAFRLAELLAALMGLFILLVILAQVAGRYLGFVVPSALEMAGFATAGLIFLGLAPTLRAGGHIRVGLLLRRLPPGPRRVAESLSLGLGLLAALYAGLQAWLRVGESYRFGDLAPGLLPLPLWLPQTFLALGLTFFALALLEAFLRALKGVAP
>NZ_AP017920.1|WP_096412785.1|2078424_2079726_-|TRAP-transporter-large-permease-subunit
MSLLEAGLLLVLGLFLLLALGVYVGLALLLVGLFGLAFLTSAPPGPNLATALWTSTSGFSLAALPLFVWMGEILYRSRLAQGLFQGLSPLLSRLPGGLLHVNVVASALFAAVIGSSAATTATVGRFTLPELLRRGYPKPLALGSLAGAGTLGFLIPPSVVMIVYGVMAEVSVARLFMAGVVPGVVLTLLFMLLLALLALARRGELPQEPPKPLGEALKSLLGVLPILFLILLVLGSIYLGVATPTEAAAIGVVGALFLAALNRELSLDTFRQSLLGAVRTTSMIGLILAGAGVLTLAMGFTGIPRALAAWAVEAGITPLLLILFLSLVYIVLGWFLDGISIVVLTISVILPVVKAIGVDPLWFGVYLVIMVELAQITPPVGFNLFVLQSLSGEDLFRIARYSLPFMGVLLLMVALLVAFPGLATWLPRTMTGG
>NZ_AP017920.1|WP_096412813.1|2092270_2092543_+|CRISPR-associated-endonuclease-Cas2
MGKRLYAVVYDISDDTRRVKLANLLKSYGERVQLSVFECYLDERLLEDLRRRAGRLLDLGQDALRIYPVAGRVEVLGVGPLPEPREVQVL
>NZ_AP017920.1|WP_096412817.1|2095006_2095411_+|type-III-A-CRISPR-associated-protein-Csm2
MPALEFFKDKARGVLDPRVFERAREVAERLARGKLKSSQFRNYFAELRALENRFAQERRKEGEELAFARLVPQLELLKAKLFYNTRSQGPLKDAREFVEFMEEALEAGKRSPKDFEAMMKYVEAVLAYFYAVGK
>NZ_AP017920.1|WP_096412819.1|2095421_2096147_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MKLKKVIRIRSVLLAKTGLRIGMSRDQMAIGDLDNPVVRNPLTDEPYIPGSSLKGKLRYLLEWSLGGDYILKAKDKHVYASPDPKDPVARIFGLAPENDEKSLAVARERGPTRLLVRDAYLTEDAKEALERTSARGGLYTEIKQEVFIPRLGGNANPRTTERVPAGARFKVEMTYRVLDDLDEEYFGKYLLRALELLELDGLGGHISRGYGQVYFLHPERLAEDQEGWPLRERLKVEEVVL
>NZ_AP017920.1|WP_172844687.1|2097026_2098151_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MGFLRSFRLELEALSPVHVGTGEAYPAYAYVPDFGRKEVHLLDPGTLLLALPEARRRQYLEKVAQGPKAAQEVLRHLLEEGQLPREAILHTLPASKAFLETLRSATEEALLEYRPLPRSPLGAYLPGSSVKGALRTAWLFHVLVERDQVAEWDRRAGVWRLRPGDGEARIYPSRDPGLYENQAFEGAVLGYAREGKGGRGMVLDLYRDPFRAVRLADSGPTPTFLNRLGVFHPGKDTSGMALLAETFRMGTRFALALRYHEGLGVSMPVPPEALVRALRDYYGKVAEWEEGFAEEHGLKRALEVYRALRERLRDPEAFPLRVGFGSGRLALRLALLLPEDHPEAQEPKTRKTAGAQNPVDGYPLGWMVGKLEPL
>NZ_AP017920.1|WP_096412826.1|2098161_2099556_+|type-III-A-CRISPR-associated-protein-Csm6
MEDLDTLWERYREAVRAGGNPQALYQEMVWPALLALWREKPRVYPAPQAFAVSVHTLGTSPEATALAILGTGAEQVYVLHTPESARFLPRLRQDTGKDLYPVEIGKSDVEAIYREVKRLLEKHPEVPVALDLTSGTKAMSAGLAAAGFFFQRFYPKVRVVYVDNEDYDPELRRPRAGTEKLRILPNPHEALAEVDALFAKELYGKGEFGQAAAYFRGMVGRTGNQAYALYALLAEMYRAWRALDFGEALKAGRKLLGQLSQNVWLNHPLNARREALEAQVALLEAVDRFLKARDFALGEGVYGLARTLLHLAQGAKEEASVLAALYAYRALELLLQERLARLGRRAEAPGLSPEEAEALRGALAELLGVDPEEVRLSPKLGLLDLLAFLRLKGDEGLGRIPLEELRGLAGVLKGRNSALLVHGFDVPSAKEVERIARLAQGLLQDLEARLGLGPLSPEPVPLGF
>NZ_AP017920.1|WP_096412829.1|2099703_2100933_+|YeeE/YedE-family-protein
MERSARPQPLALGLFALGFAVLSHLVYQTSGPRLLLAFWVAVLLGLTLFHAKFGFASGFRRFLLTGESRLLRAHFLLFALTALFFFPFLKEGEAFGLPVQGFLVPLGVALAVGAFLFGVGMQLGDGCASGTLYHTGSGDTRGLLVLLGFMAGSLLGVYHLPFWQALPAWTPGSALTWFPSPYLGLALWMGLLAALYLGVSQVERRRRGRLEPLLRQEATHPLFGPWSLAAGAFLLALGSLLLLLLQGRPWGVTAAFALWGGKLAQALGVPVLDWALFHNPAFAERLQESVLRDATSVTNFGLFLGAFLGAALSGSLRLKDLRRIPWSTHLGVFLGGVLMGYGARLAGGCNIGAYLGGTASFSLHGPLWGVFALLGTALGVRLRPVCRLENEGGSAPQAGGKEGLEAHRV
>NZ_AP017920.1|WP_096412833.1|2101260_2101926_+|DUF4397-domain-containing-protein
MKRGFFAMVLTGLVGLALGQGAMVRVAHLSPDAPAVDVLVNGQRAITGLAFKEVTPYLPLPAAKVRVQVVPAGQDAPVVMDAELDLKEGVYYTVAATGFLAQIRPQVYTDLLAGFFPRAGYARIRVVHASPDAPAVDVAVKGGPVLFAGLPFPQASPYLSVAAGTYDLEVRAAGTDTVALSLPGVELEPGKVYTVFAVGSLKEGTLTVVPVVDATALGGNR
>NZ_AP017920.1|WP_096412837.1|2101912_2102665_+|methyltransferase-domain-containing-protein
MGTAEAPKPPFPGPPEEGVPPWLPPLLACPFCRGPLLEEGCPGCGRAFPWKGGFLDLRAFRERPLLALVNRFPPVALGYDLWRTRSTGLLSGGRLDLAGELALLREWLLPTGGPFLDVGTGTGVYREALGEGMVGVDPSPTFLRVARKRRPGAYLLAHGERLPFREGAFGGVAIGPTWNEFLDPEGAAREARRVLRPGGRLFGLLLLGPGASLGLFRPSPEALLRLLEGAGFRAEVRRLGLIGLVLAEVG
>NZ_AP017920.1|WP_172844688.1|2102670_2103939_+|alpha/beta-fold-hydrolase
MRRLLAFSLALLLAQGQEYRALPGADTGRPDLDHSYALVYPAPRPKALLLVPGLLGGSTNFALLAEHLRALDPDLEVWAWERRANGLEDRRGFLQEDPVAYYRRMPLPDLTPLRAWGLEVHLKDLDLAVEEARRRAPVVLGGHSLGAALAGLYALLHGEKLSGLVLLDGAPGVARLTEEAFYEGTDLPFGRFVGYRAFLRGEGSPVVEFLGLGPKALALAEAEAFLAARRPEEVLPFGPYRATREALALLRVDDDYSLLPVFSVGVGRAWAREGFSLLGLLQGRLVRTVRGPRAGPVAWRDTGKATDPRAFLRAFALPETGFSEWYFPYRLLLEVGGYPYVLRGLKPRALPYPVLALGAGRGLYPRAEDFPLGELFPGTEARAQVLPGLTHLDLLTEREGRTAGLLLRYLQGLGLLGPGGPP
>NZ_AP017920.1|WP_096412842.1|2103853_2105257_-|FAD-dependent-oxidoreductase
MRALVVGAGIGGLVAARALQKAGLEVLVLEAHTYPGGLAGTFTHRGHRLDAGATLLSGFAPGAPLALAAEALGMRFPLEPLPEGFPLLEVHLPRGRVVRPVGREAEREAQRDFFGPRVLPFWRWQEERAKALLRLAPRLPWPPEREELPRLLALVPGLLPLLPDLFLKAVHRAPQDPHFLRFLDAQLLIASQAEAGRTYALYAALALDLPHMGPALAPEGVGRVAEALAEGLPVRYKARAERLLLREGRAFAVEVAYGGRRRGEREVVEADLFVLDVPLAPLLGLPLKAPKDAWGAFVVHGVLPFRAPPPYFRQNAREKPFAFLSLRPEGEKTAFALSLHTPLALWEGLSREEYGRLKARWGEMALRLGEALLPGLREAEFLLFGTPRTYARFAGRAWVGGYPQTHPFRFPRVRPFPNVFRVGEGVFPGQSVPAAALSGLRAARLALEALGLAGSEGEARPSFPPSP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP017920_1	1.13\|97764\|38\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	97764-97801	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	49319-49356	0	1.0
NZ_AP017920_1	1.3\|97090\|39\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	97090-97128	39	LC210520	Thermus phage phiOH16 genomic DNA, complete genome	95-133	1	0.974
NZ_AP017920_2	2.1\|108917\|38\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	108917-108954	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	407923-407960	1	0.974
NZ_AP017920_1	1.13\|97764\|38\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	97764-97801	38	NZ_LR027519	Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence	58196-58233	2	0.947
NZ_AP017920_1	1.13\|97764\|38\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	97764-97801	38	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	125040-125077	2	0.947
NZ_AP017920_5	5.1\|1686905\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	1686905-1686941	37	NZ_LR027519	Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence	33708-33744	3	0.919
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	53127-53163	4	0.892
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	121236-121272	4	0.892
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NZ_LR027519	Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence	61962-61998	4	0.892
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NZ_CP020572	Thermus aquaticus strain YT-1 plasmid p61, complete sequence	3456-3492	5	0.865
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NZ_CP010825	Thermus aquaticus Y51MC23 plasmid pTA69, complete sequence	23492-23528	5	0.865
NZ_AP017920_1	1.8\|97430\|36\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	97430-97465	36	NC_004462	Thermus thermophilus phage IN93, complete genome	6144-6179	6	0.833
NZ_AP017920_1	1.8\|97430\|36\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	97430-97465	36	AB063393	Thermus thermophilus phage IN93 DNA, complete genome	6144-6179	6	0.833
NZ_AP017920_5	5.1\|1686905\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	1686905-1686941	37	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	12665-12701	6	0.838
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	HQ317387	Sulfitobacter phage phiCB2047-B genomic sequence	40171-40204	7	0.794
NZ_AP017920_1	1.24\|98505\|33\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98505-98537	33	NC_014753	Oceanithermus profundus DSM 14977 plasmid pOCEPR01, complete sequence	60193-60225	8	0.758
NZ_AP017920_1	1.24\|98505\|33\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98505-98537	33	CP040467	Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence	6602-6634	9	0.727
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	KR093632	Moraxella phage Mcat8, complete genome	26620-26653	9	0.735
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	NZ_CP045731	Lactobacillus gastricus strain LG045 plasmid unnamed2, complete sequence	649-682	9	0.735
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	1559683-1559716	9	0.735
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	74465-74501	10	0.73
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	196248-196284	10	0.73
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NZ_LR027519	Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence	1173-1209	10	0.73
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NC_017588	Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence	28600-28636	10	0.73
NZ_AP017920_1	1.23\|98438\|37\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	98438-98474	37	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	100398-100434	10	0.73
NZ_AP017920_2	2.6\|109257\|39\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	109257-109295	39	NZ_CP015739	Shinella sp. HZN7 plasmid pShin-03, complete sequence	315470-315508	10	0.744
NZ_AP017920_4	4.9\|1162332\|32\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	1162332-1162363	32	NZ_CP023976	Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence	127840-127871	10	0.688
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	HQ670749	Cellulophaga phage phi47:1, * SEQUENCING IN PROGRESS *, 6 unordered pieces	37413-37446	10	0.706
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	KC821610	Cellulophaga phage phi3ST:2, complete genome	10608-10641	10	0.706
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	KC821634	Cellulophaga phage phi47:1, complete genome	10608-10641	10	0.706
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	KC821629	Cellulophaga phage phi38:2, complete genome	10608-10641	10	0.706
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	NC_020860	Cellulophaga phage phiSM genomic sequence	10663-10696	10	0.706
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	KC821630	Cellulophaga phage phi3:1, complete genome	10608-10641	10	0.706
NZ_AP017920_6	6.13\|2091405\|34\|NZ_AP017920\|PILER-CR,CRISPRCasFinder,CRT	2091405-2091438	34	KC821616	Cellulophaga phage phiSM, complete genome	10608-10641	10	0.706

1. spacer 1.13|97764|38|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tctcaccccctttcaacctcatacgactgccattatag	CRISPR spacer
tctcaccccctttcaacctcatacgactgccattatag	Protospacer
**************************************

2. spacer 1.3|97090|39|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to LC210520 (Thermus phage phiOH16 genomic DNA, complete genome) position: , mismatch: 1, identity: 0.974

tccggggcggtggtgtagttggccctttgaggtcgcttg	CRISPR spacer
tccgaggcggtggtgtagttggccctttgaggtcgcttg	Protospacer
****.**********************************

3. spacer 2.1|108917|38|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 1, identity: 0.974

tgatgcggcgtttcgcggtgcttctcctcggttcccta	CRISPR spacer
agatgcggcgtttcgcggtgcttctcctcggttcccta	Protospacer
 *************************************

4. spacer 1.13|97764|38|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027519 (Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence) position: , mismatch: 2, identity: 0.947

tctcaccccctttcaacctcatacgactgccattatag	CRISPR spacer
tcccaccccctttcaacctcatacgactgctattatag	Protospacer
**.***************************.*******

5. spacer 1.13|97764|38|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 2, identity: 0.947

tctcaccccctttcaacctcatacgactgccattatag	CRISPR spacer
tcccaccccctttcaacctcatacgactgctattatag	Protospacer
**.***************************.*******

6. spacer 5.1|1686905|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027519 (Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence) position: , mismatch: 3, identity: 0.919

tccttgccctcgtaggtctccgtctggagcctccctt	CRISPR spacer
tccttcccctcgtaggtctccgtctggagcctgccct	Protospacer
***** ************************** **.*

7. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 4, identity: 0.892

cccgatggcctcctccagggtgtaggggccttcccgc	CRISPR spacer
ctccagggcctcctgcagggtgtaggggccttcccgc	Protospacer
*.* * ******** **********************

8. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 4, identity: 0.892

cccgatggcctcctccagggtgtaggggccttcccgc	CRISPR spacer
ctccagggcctcctgcagggtgtaggggccttcccgc	Protospacer
*.* * ******** **********************

9. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027519 (Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence) position: , mismatch: 4, identity: 0.892

cccgatggcctcctccagggtgtaggggccttcccgc	CRISPR spacer
ctccagggcctcctgcagggtgtaggggccttcccgc	Protospacer
*.* * ******** **********************

10. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020572 (Thermus aquaticus strain YT-1 plasmid p61, complete sequence) position: , mismatch: 5, identity: 0.865

cccgatggcctcctccagggtgtaggggccttcccgc	CRISPR spacer
ctccctggcctcctccagggtgaaggggccttccagc	Protospacer
*.*  ***************** *********** **

11. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010825 (Thermus aquaticus Y51MC23 plasmid pTA69, complete sequence) position: , mismatch: 5, identity: 0.865

cccgatggcctcctccagggtgtaggggccttcccgc	CRISPR spacer
ctccctggcctcctccagggtgaaggggccttccagc	Protospacer
*.*  ***************** *********** **

12. spacer 1.8|97430|36|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_004462 (Thermus thermophilus phage IN93, complete genome) position: , mismatch: 6, identity: 0.833

gccccgagttccaggcgtacggcggcaggcagaaaa	CRISPR spacer
gccccgagttccaggcgtacaccggcaggcagcggg	Protospacer
********************. ********** ...

13. spacer 1.8|97430|36|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to AB063393 (Thermus thermophilus phage IN93 DNA, complete genome) position: , mismatch: 6, identity: 0.833

gccccgagttccaggcgtacggcggcaggcagaaaa	CRISPR spacer
gccccgagttccaggcgtacaccggcaggcagcggg	Protospacer
********************. ********** ...

14. spacer 5.1|1686905|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 6, identity: 0.838

tccttgccctcgtaggtctccgtctggagcctccctt	CRISPR spacer
tccttggcctcgtaggtctcggtctggaggcggccct	Protospacer
****** ************* ******** *  **.*

15. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to HQ317387 (Sulfitobacter phage phiCB2047-B genomic sequence) position: , mismatch: 7, identity: 0.794

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tcttcttctttgtttggttcttttactggtactt	Protospacer
*.*  ******************* .**** * *

16. spacer 1.24|98505|33|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_014753 (Oceanithermus profundus DSM 14977 plasmid pOCEPR01, complete sequence) position: , mismatch: 8, identity: 0.758

tgagaggggggtagacctccttcacctcctcgc	CRISPR spacer
gcagggtcaggtagaccttcttcacctcgtcgc	Protospacer
  **.*  .*********.********* ****

17. spacer 1.24|98505|33|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to CP040467 (Streptomyces albidoflavus strain UYFA156 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

tgagaggggggtagacctccttcacctcctcgc	CRISPR spacer
aggccgccgggtcgacctccttcagctcctcgg	Protospacer
 *.  *  **** *********** *******

18. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to KR093632 (Moraxella phage Mcat8, complete genome) position: , mismatch: 9, identity: 0.735

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
cttggttctttgttaggtgcttttttggcagcca	Protospacer
.************* *** ******* *   *

19. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045731 (Lactobacillus gastricus strain LG045 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
gtctggcctttgtttggttctttagttggttttt	Protospacer
 *. * .****************  ******. *

20. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 9, identity: 0.735

tttggttctttgtttggttctttttt-tggttcgt	CRISPR spacer
catggttatttgtttggttcttctttaccaatcg-	Protospacer
. ***** **************.*** . . ***

21. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 10, identity: 0.73

cccgatggcctcctccagggt------gtaggggccttcccgc	CRISPR spacer
ccggatggcctcctccagggtgttggcgtaggagacg------	Protospacer
** ******************      *****.* *

22. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 10, identity: 0.73

cccgatggcctcctccagggt------gtaggggccttcccgc	CRISPR spacer
ccggatggcctcctccagggtgttggcgtaggagacg------	Protospacer
** ******************      *****.* *

23. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027519 (Thermus thermophilus isolate TTHNAR1 plasmid 3, complete sequence) position: , mismatch: 10, identity: 0.73

cccgatggcctcctccagggt------gtaggggccttcccgc	CRISPR spacer
ccggatggcctcctccagggtgttggcgtaggagacg------	Protospacer
** ******************      *****.* *

24. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_017588 (Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence) position: , mismatch: 10, identity: 0.73

cccgatggcctcctccagggt------gtaggggccttcccgc	CRISPR spacer
ccggatggcctcctccagggtgttggcgtaggagacg------	Protospacer
** ******************      *****.* *

25. spacer 1.23|98438|37|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 10, identity: 0.73

cccgatggcctcctccagggt------gtaggggccttcccgc	CRISPR spacer
ccggatggcctcctccagggtgttggcgtaggagacg------	Protospacer
** ******************      *****.* *

26. spacer 2.6|109257|39|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015739 (Shinella sp. HZN7 plasmid pShin-03, complete sequence) position: , mismatch: 10, identity: 0.744

cctgcgcttcgccaccggagaccgcctgcggctggacgg	CRISPR spacer
ggacggcttcgccaccggggaccggctgcggctgcaggc	Protospacer
     *************.***** ********* * *

27. spacer 4.9|1162332|32|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023976 (Streptomyces alboflavus strain MDJK44 plasmid pMDJK44.1, complete sequence) position: , mismatch: 10, identity: 0.688

agcgtcacggtcacgaggttggaggaggtccg	CRISPR spacer
cagagcacggtcacgaggatggagaaggccga	Protospacer
 . . ************* *****.***.* .

28. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to HQ670749 (Cellulophaga phage phi47:1, *** SEQUENCING IN PROGRESS ***, 6 unordered pieces) position: , mismatch: 10, identity: 0.706

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tgctgttctttgcttggttctttttatgtctatg	Protospacer
* . ********.************ ** .*

29. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to KC821610 (Cellulophaga phage phi3ST:2, complete genome) position: , mismatch: 10, identity: 0.706

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tgctgttctttgcttggttctttttatgtctatg	Protospacer
* . ********.************ ** .*

30. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to KC821634 (Cellulophaga phage phi47:1, complete genome) position: , mismatch: 10, identity: 0.706

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tgctgttctttgcttggttctttttatgtctatg	Protospacer
* . ********.************ ** .*

31. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to KC821629 (Cellulophaga phage phi38:2, complete genome) position: , mismatch: 10, identity: 0.706

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tgctgttctttgcttggttctttttatgtctatg	Protospacer
* . ********.************ ** .*

32. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to NC_020860 (Cellulophaga phage phiSM genomic sequence) position: , mismatch: 10, identity: 0.706

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tgctgttctttgcttggttctttttatgtctatg	Protospacer
* . ********.************ ** .*

33. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to KC821630 (Cellulophaga phage phi3:1, complete genome) position: , mismatch: 10, identity: 0.706

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tgctgttctttgcttggttctttttatgtctatg	Protospacer
* . ********.************ ** .*

34. spacer 6.13|2091405|34|NZ_AP017920|PILER-CR,CRISPRCasFinder,CRT matches to KC821616 (Cellulophaga phage phiSM, complete genome) position: , mismatch: 10, identity: 0.706

tttggttctttgtttggttctttttttggttcgt	CRISPR spacer
tgctgttctttgcttggttctttttatgtctatg	Protospacer
* . ********.************ ** .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

75960 : 118845

uncultured_virus(100.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096410480.1\|75960_77058_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_096410481.1\|84330_85584_-	MFS transporter	NA	NA	NA	NA
WP_096410482.1\|85597_86392_-	carbohydrate deacetylase	NA	NA	NA	NA
WP_172844612.1\|87458_88370_-	hypothetical protein	NA	NA	NA	NA
WP_096410484.1\|88390_88762_-	hypothetical protein	NA	NA	NA	NA
WP_096410485.1\|89199_90045_-\|transposase	transposase	NA	NA	NA	NA
WP_096410486.1\|90061_90718_-	hypothetical protein	NA	NA	NA	NA
WP_041444900.1\|93424_94525_+\|transposase	transposase	NA	NA	NA	NA
WP_096410488.1\|94902_95808_-	hypothetical protein	NA	NA	NA	NA
WP_096410489.1\|95819_96809_-	type III-B CRISPR module RAMP protein Cmr1	NA	NA	NA	NA
WP_096410490.1\|99247_100345_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_096410491.1\|100410_101394_-	type I-B CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_096410492.1\|101386_101908_-	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_096412881.1\|104171_104900_+	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_096410495.1\|104892_106788_+	hypothetical protein	NA	NA	NA	NA
WP_096410496.1\|106768_107734_+	type I-B CRISPR-associated protein Cas7/Csh2	NA	NA	NA	NA
WP_096410497.1\|107661_108264_+	CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_096410498.1\|108445_108706_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_096410480.1\|111727_112825_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_096410499.1\|113139_113802_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_096410500.1\|113794_114709_+	cytosolic protein	NA	NA	NA	NA
WP_096410501.1\|114705_115416_+	PIG-L family deacetylase	NA	NA	NA	NA
WP_096410502.1\|115428_116097_+	4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase	NA	NA	NA	NA
WP_096410503.1\|117624_118845_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	6.3e-23	35.4

DBSCAN-SWA_2

440278 : 510745

Prochlorococcus_phage(15.38%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096410728.1\|440278_440941_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_096410729.1\|440937_441543_-	hypothetical protein	NA	NA	NA	NA
WP_096410730.1\|441517_443974_-	CBS domain-containing protein	A0A0U4J6Z1	Vibrio_phage	9.8e-15	33.7
WP_096410731.1\|444217_445837_+	hypothetical protein	NA	NA	NA	NA
WP_096410732.1\|445843_446476_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.1e-30	40.1
WP_096410733.1\|447109_447601_+	OmpH family outer membrane protein	NA	NA	NA	NA
WP_096410734.1\|447641_450245_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.8e-84	51.5
WP_096410735.1\|450287_450689_+	S-adenosylmethionine decarboxylase	NA	NA	NA	NA
WP_096410736.1\|450700_451645_+	polyamine aminopropyltransferase	A0A1C9C533	Heterosigma_akashiwo_virus	5.6e-19	33.9
WP_096410737.1\|451680_452316_+	DsbA family protein	NA	NA	NA	NA
WP_096410738.1\|452358_453906_+	cation:proton antiporter	NA	NA	NA	NA
WP_096410739.1\|453874_454609_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_096410740.1\|454850_455108_+	DUF4212 domain-containing protein	NA	NA	NA	NA
WP_096410741.1\|455117_456791_+	cation acetate symporter	NA	NA	NA	NA
WP_096410742.1\|461563_461926_+	response regulator	NA	NA	NA	NA
WP_096410743.1\|461922_463797_+	PAS domain-containing protein	A0A0N9SJX9	Paenibacillus_phage	6.1e-17	33.1
WP_096410744.1\|463786_465040_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_172844625.1\|465036_465924_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	1.8e-27	35.2
WP_172844626.1\|465924_466125_-	hypothetical protein	NA	NA	NA	NA
WP_096412946.1\|466109_466823_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_096410745.1\|467616_468150_-	glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_096410746.1\|469285_469726_+	YqhA family protein	NA	NA	NA	NA
WP_096410747.1\|469725_470391_+	hypothetical protein	NA	NA	NA	NA
WP_096410748.1\|470401_471520_+	aminofutalosine synthase MqnE	NA	NA	NA	NA
WP_096410749.1\|472396_472933_+	YceI family protein	NA	NA	NA	NA
WP_096410750.1\|472933_473332_+	hypothetical protein	NA	NA	NA	NA
WP_096410751.1\|473328_474093_+	VOC family protein	NA	NA	NA	NA
WP_096410752.1\|474233_475268_+	3-deoxy-7-phosphoheptulonate synthase	E3T537	Cafeteria_roenbergensis_virus	4.3e-12	28.0
WP_096410753.1\|475264_476344_+	prephenate dehydrogenase/arogenate dehydrogenase family protein	NA	NA	NA	NA
WP_096410754.1\|476328_477279_-	GGDEF domain-containing protein	G3MA91	Bacillus_virus	2.3e-12	31.1
WP_096410755.1\|477333_478689_-	FAD-binding protein	NA	NA	NA	NA
WP_096410756.1\|478698_479181_-	hypothetical protein	NA	NA	NA	NA
WP_096410757.1\|479250_479703_+	EVE domain-containing protein	NA	NA	NA	NA
WP_096410758.1\|479677_480898_-	type II secretion system F family protein	NA	NA	NA	NA
WP_096410759.1\|480896_481484_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	5.7e-22	37.9
WP_096410760.1\|481487_482018_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.7e-17	36.8
WP_096410761.1\|481961_483044_-	PIG-L family deacetylase	NA	NA	NA	NA
WP_096410762.1\|483077_483704_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_096410763.1\|484903_485782_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_096410764.1\|487098_488034_+	D-glycerate dehydrogenase	A0A2R8FDS8	Brazilian_cedratvirus	2.7e-34	33.5
WP_096410765.1\|488039_488777_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_096410766.1\|489079_489625_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_096410767.1\|489621_490527_+	aspartate carbamoyltransferase catalytic subunit	M1HWF9	Paramecium_bursaria_Chlorella_virus	2.8e-28	31.8
WP_172844606.1\|490546_490696_+	hypothetical protein	NA	NA	NA	NA
WP_096410768.1\|490667_491132_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_096410769.1\|491128_492409_+	dihydroorotase	NA	NA	NA	NA
WP_096410770.1\|492413_492893_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_096410771.1\|492936_493974_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_096410772.1\|494021_494531_+	hypothetical protein	NA	NA	NA	NA
WP_041444900.1\|499467_500568_+\|transposase	transposase	NA	NA	NA	NA
WP_015065468.1\|502442_503108_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_096410485.1\|503334_504180_+\|transposase	transposase	NA	NA	NA	NA
WP_096410773.1\|504515_505232_-\|transposase	transposase	NA	NA	NA	NA
WP_096410774.1\|505580_506567_-	P1 family peptidase	NA	NA	NA	NA
WP_096410775.1\|508760_509465_+	SDR family oxidoreductase	A0A0K0KVL6	Prochlorococcus_phage	1.0e-04	25.1
WP_008632164.1\|509474_509885_+	SufE family protein	NA	NA	NA	NA
WP_157745757.1\|510253_510745_-\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1350127 : 1425088

Streptococcus_phage(18.75%)

transposase,tRNA,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096411374.1\|1350127_1351537_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_096411375.1\|1351547_1352633_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_096411376.1\|1352645_1355315_-	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_096411377.1\|1355311_1355797_-	YqeG family HAD IIIA-type phosphatase	NA	NA	NA	NA
WP_096411378.1\|1355831_1356560_-	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_096411379.1\|1356556_1357312_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.4e-42	41.8
WP_096411380.1\|1357370_1357577_-	cold-shock protein	Q9AZD3	Lactococcus_phage	2.4e-15	61.4
WP_096410490.1\|1357738_1358836_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_096411381.1\|1358916_1360206_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_096411382.1\|1360257_1361133_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_096411383.1\|1361129_1361972_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_096411384.1\|1361978_1363553_-	alpha-D-glucose phosphate-specific phosphoglucomutase	A0A1X9I671	Streptococcus_phage	2.1e-18	27.2
WP_096411385.1\|1363608_1365417_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_096411386.1\|1365637_1366774_+	MFS transporter	NA	NA	NA	NA
WP_096411387.1\|1366783_1368370_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_096411388.1\|1368691_1369039_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_096411389.1\|1369051_1369966_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.4e-75	49.3
WP_096411390.1\|1370074_1370524_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_096411391.1\|1370581_1371487_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_011174007.1\|1371529_1371925_+	transcriptional repressor	NA	NA	NA	NA
WP_096411392.1\|1371925_1373170_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_096411393.1\|1373172_1374303_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_096411395.1\|1374295_1374790_-	MogA/MoaB family molybdenum cofactor biosynthesis protein	NA	NA	NA	NA
WP_096411396.1\|1374796_1375489_-	hypothetical protein	NA	NA	NA	NA
WP_096411398.1\|1375536_1376976_+	abortive phage infection protein	NA	NA	NA	NA
WP_096411400.1\|1376975_1377743_+	SAM-dependent chlorinase/fluorinase	NA	NA	NA	NA
WP_096411402.1\|1377831_1378236_+	DUF4395 family protein	NA	NA	NA	NA
WP_096411403.1\|1378222_1378696_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	3.2e-23	40.4
WP_096413055.1\|1378716_1379094_+	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_096411405.1\|1379098_1379431_+	DUF190 domain-containing protein	NA	NA	NA	NA
WP_096411407.1\|1379524_1380139_+	sulfite oxidase-like oxidoreductase	NA	NA	NA	NA
WP_096411409.1\|1380161_1380428_+	hypothetical protein	NA	NA	NA	NA
WP_096411410.1\|1380403_1381207_-	histidinol-phosphatase HisJ family protein	NA	NA	NA	NA
WP_096411412.1\|1381196_1381796_-	hypothetical protein	NA	NA	NA	NA
WP_096411414.1\|1381810_1382401_-	cysteine hydrolase	A0A2K9L6K4	Tupanvirus	9.5e-17	36.6
WP_096411416.1\|1382460_1383345_+	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_096411418.1\|1383473_1384445_+	cell division protein ZapE	NA	NA	NA	NA
WP_096411420.1\|1384454_1384703_+	hypothetical protein	NA	NA	NA	NA
WP_096411422.1\|1384699_1385845_+	phosphopentomutase	NA	NA	NA	NA
WP_096411424.1\|1385848_1386574_+	TIGR00159 family protein	NA	NA	NA	NA
WP_096411426.1\|1386566_1387376_+	hypothetical protein	NA	NA	NA	NA
WP_096411427.1\|1387381_1387960_+	peptide deformylase	E3SLL2	Synechococcus_phage	3.5e-16	38.3
WP_096411429.1\|1387956_1388874_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	5.8e-13	29.5
WP_096411431.1\|1389683_1390910_+	YvcK family protein	A1IMD5	Streptococcus_phage	2.1e-34	34.2
WP_096411432.1\|1391567_1392011_-	hypothetical protein	NA	NA	NA	NA
WP_172844696.1\|1393116_1394220_+	MFS transporter	NA	NA	NA	NA
WP_096411436.1\|1394793_1395033_+	hypothetical protein	NA	NA	NA	NA
WP_096411437.1\|1395316_1396108_-\|transposase	transposase	NA	NA	NA	NA
WP_096410490.1\|1396151_1397249_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_157745806.1\|1398020_1398512_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_096411441.1\|1398546_1399767_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	8.3e-23	36.0
WP_096411443.1\|1399803_1400034_+	hypothetical protein	NA	NA	NA	NA
WP_157745808.1\|1400368_1400686_+	hypothetical protein	NA	NA	NA	NA
WP_157745810.1\|1400676_1401078_+	peptidoglycan DD-metalloendopeptidase family protein	A0A222YWR8	Streptomyces_phage	2.3e-06	50.9
WP_096411447.1\|1401204_1401567_+	hypothetical protein	NA	NA	NA	NA
WP_157745812.1\|1401898_1402225_-\|transposase	transposase	NA	NA	NA	NA
WP_096410503.1\|1402290_1403511_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	6.3e-23	35.4
WP_157745814.1\|1403494_1403920_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	6.0e-05	30.6
WP_096411067.1\|1404252_1404459_-\|transposase	transposase	NA	NA	NA	NA
WP_172844661.1\|1404626_1405151_+	hypothetical protein	NA	NA	NA	NA
WP_096411452.1\|1405197_1405866_+	queuosine precursor transporter	A0A1W7AG82	Streptococcus_virus	1.5e-29	40.4
WP_014628934.1\|1407990_1408782_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_096411454.1\|1409864_1410749_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_096411456.1\|1410853_1411279_+	DUF2203 domain-containing protein	NA	NA	NA	NA
WP_096411458.1\|1411229_1411622_-	metallopeptidase family protein	NA	NA	NA	NA
WP_096411459.1\|1411618_1412032_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_096411461.1\|1412162_1413266_+	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
WP_096411463.1\|1413275_1414250_+	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_096411464.1\|1414251_1414455_+	2-oxoisovalerate dehydrogenase	NA	NA	NA	NA
WP_096411466.1\|1414451_1414697_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_096411468.1\|1414707_1416057_+	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_172844662.1\|1416067_1417453_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.9e-40	27.8
WP_093007113.1\|1417449_1417722_-	AzlD domain-containing protein	NA	NA	NA	NA
WP_096411472.1\|1417718_1418369_-	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_096411474.1\|1418436_1418682_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_096410485.1\|1418709_1419555_-\|transposase	transposase	NA	NA	NA	NA
WP_096411475.1\|1419941_1420976_+	phosphoadenosine phosphosulfate reductase family protein	R9TRT5	Rhizobium_phage	1.0e-34	32.3
WP_096411477.1\|1420981_1422109_+	hypothetical protein	NA	NA	NA	NA
WP_172844663.1\|1424016_1424586_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157745757.1\|1424596_1425088_+\|transposase	IS630 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP017920

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection