CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_AP017932	Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence	1 crisprs	NA	2	0
NZ_AP017933	Lactobacillus sakei strain LK-145 plasmid pLs145-b, complete sequence	0 crisprs	NA	0	0
NZ_AP017931	Lactobacillus sakei strain LK-145	1 crisprs	cas3,DEDDh,DinG,csa3	0	6
NZ_AP017934	Lactobacillus sakei strain LK-145 plasmid pLs145-c, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP017932_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017932_1

21877-22027

Orphan

Consensus_repeat	Method
AAAGTAAACATGTATACATT	PILER-CR

2 spacers

The CRISPR arrays of NZ_AP017932_1

>merge|NZ_AP017932|1|21877-22027|PILER-CR
AATGTAAACATGTATACATTGGAAGGTACGATAAATATTTTGTTTACTTGTATTAATGTAAAAAAGTAAATATGTATACATTTTTACACATAATAATACCTATAAATAAGCAATACACAACTTTTAATACTAAAGTAAACATGTATACATT

>NZ_AP017932|1|1|21877-22027|PILER-CR
AATGTAAACATGTATACATT	GGAAGGTACGATAAATATTTTGTTTACTTGTATTAATGTAAA
AAAGTAAATATGTATACATT	TTTACACATAATAATACCTATAAATAAGCAATACACAACTTTTAATACT
AAAGTAAACATGTATACATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017932.1\|WP_003587210.1\|30556_31024_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|153102
NZ_AP017932.1\|WP_096585854.1\|32424_33015_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271192
NZ_AP017932.1\|WP_096585839.1\|14768_15383_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017932.1\|WP_016265840.1\|24925_25876_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_AP017932.1\|WP_016265853.1\|22102_22918_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NZ_AP017932.1\|WP_096585845.1\|23855_24785_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_AP017932.1\|WP_096585843.1\|20556_21555_-\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|369151
NZ_AP017932.1\|WP_096585841.1\|18035_18857_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NZ_AP017932.1\|WP_015474680.1\|17767_18046_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017932.1\|WP_076631995.1\|29098_29557_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179443
NZ_AP017932.1\|WP_099769415.1\|16368_17438_-\|IS3-like-element-IS1520-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_AP017932.1\|WP_025016512.1\|26923_29071_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|180921
NZ_AP017932.1\|WP_076648311.1\|14431_14767_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|374896
NZ_AP017932.1\|WP_003555660.1\|17517_17745_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP017932.1\|WP_096585852.1\|31586_32417_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198394
NZ_AP017932.1\|WP_076648347.1\|25890_26817_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_AP017932.1\|WP_035145350.1\|22910_23261_+\|DUF5388-domain-containing-protein	unknown	unknown	gnl\|CDD\|375154
NZ_AP017932.1\|WP_025085233.1\|13419_14079_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|273346
NZ_AP017932.1\|WP_014216295.1\|14047_14410_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274860
NZ_AP017932.1\|WP_096585837.1\|11392_13408_-\|DUF87-domain-containing-protein	unknown	unknown	gnl\|CDD\|274279

Protein	Function_ID	Function_description	E-value
NZ_AP017932.1\|WP_003587210.1\|30556_31024_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|153102	cd01043, DPS, DPS protein, ferritin-like diiron-binding domain. DPS (DNA Protecting protein under Starved conditions) domain is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Some DPS proteins nonspecifically bind DNA, protecting it from cleavage caused by reactive oxygen species such as the hydroxyl radicals produced during oxidation of Fe(II) by hydrogen peroxide. These proteins assemble into dodecameric structures, some form DPS-DNA co-crystalline complexes, and possess iron and H2O2 detoxification capabilities. Expression of DPS is induced by oxidative or nutritional stress, including metal ion starvation. Members of the DPS family are homopolymers formed by 12 four-helix bundle subunits that assemble with 23 symmetry into a hollow shell. The DPS ferroxidase site is unusual in that it is not located in a four-helix bundle as in ferritin, but is shared by 2-fold symmetry-related subunits providing the iron ligands. Many DPS sequences (e.g., E. coli) display an N-terminal extension of variable length that contains two or three positively charged lysine residues that extends into the solvent and is thought to play an important role in the stabilization of the complex with DNA. DPS Listeria Flp, Bacillus anthracis Dlp-1 and Dlp-2, and Helicobacter pylori HP-NAP which lack the N-terminal extension, do not bind DNA. DPS proteins from Helicobacter pylori, Treponema pallidum, and Borrelia burgdorferi are highly immunogenic.	5.65789e-47
NZ_AP017932.1\|WP_096585854.1\|32424_33015_+\|site-specific-integrase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	4.82066e-65
NZ_AP017932.1\|WP_016265840.1\|24925_25876_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	5.03856e-178
NZ_AP017932.1\|WP_016265853.1\|22102_22918_+\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	4.14334e-51
NZ_AP017932.1\|WP_096585845.1\|23855_24785_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.6009e-66
NZ_AP017932.1\|WP_096585843.1\|20556_21555_-\|replication-initiator-protein-A	gnl\|CDD\|369151	pfam06970, RepA_N, Replication initiator protein A (RepA) N-terminus. This of family of predicted proteins represents the N-terminus (approximately 80 residues) of replication initiator protein A (RepA), a DNA replication initiator in plasmids. Most proteins in this family are bacterial, but archaeal and eukaryotic members are also included.	4.98942e-29
NZ_AP017932.1\|WP_096585841.1\|18035_18857_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	0.000145537
NZ_AP017932.1\|WP_076631995.1\|29098_29557_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179443	PRK02551, PRK02551, flavoprotein NrdI; Provisional.	7.30361e-64
NZ_AP017932.1\|WP_099769415.1\|16368_17438_-\|IS3-like-element-IS1520-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.9979e-35
NZ_AP017932.1\|WP_025016512.1\|26923_29071_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|180921	PRK07306, PRK07306, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_AP017932.1\|WP_096585837.1\|11392_13408_-\|DUF87-domain-containing-protein	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	1.87989e-28
NZ_AP017932.1\|WP_096585852.1\|31586_32417_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198394	cd10447, GIY-YIG_unchar_2, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria and archaea. The family includes a group of uncharacterized hypothetical proteins, mainly found in bacteria and a few found in archaea, with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	1.01533e-19
NZ_AP017932.1\|WP_076648347.1\|25890_26817_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	9.29195e-61
NZ_AP017932.1\|WP_035145350.1\|22910_23261_+\|DUF5388-domain-containing-protein	gnl\|CDD\|375154	pfam17363, DUF5388, Family of unknown function (DUF5388). This is a family of unknown function found in Lactobacillales.	5.187e-25
NZ_AP017932.1\|WP_025085233.1\|13419_14079_-\|conjugal-transfer-protein	gnl\|CDD\|273346	TIGR00929, CAG_pathogenicity_island_protein_23, type IV secretion/conjugal transfer ATPase, VirB4 family. Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).	0.00134284
NZ_AP017932.1\|WP_014216295.1\|14047_14410_-\|hypothetical-protein	gnl\|CDD\|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0.00203
NZ_AP017932.1\|WP_076648311.1\|14431_14767_-\|conjugal-transfer-protein	gnl\|CDD\|374896	pfam16943, T4SS_CagC, Cag pathogenicity island, type IV secretory system. T4SS_CagC is a family of putative pathogenicity island, type IV, conjugal DNA-protein transfer, secretory system proteins from Gram-negative bacteria.	1.59817e-43

>NZ_AP017932.1|WP_096585843.1|20556_21555_-|replication-initiator-protein-A
MDNQLNYYNIKREYALKFFQVPKVFMTNDKYKKLSAEAKLAFAILSDRLQLSIKNHWFDKAGNIYFIYTGEQLEQILGCGHSKITSIKKELTEAQLLVMKRMGQGKANRMYLLGPEITDNDIYGIDQLETAENPLAEEVVNIDLPTSMNDGQPETLDKSRLLKNSNLDYRKTVTSDTDINNTEYLKTLNTDTKKTDTLTDSPQNIKQLQDAALFEVQLENDNIFSKQQLLALKLLSNGDFELFCTVQKTILRAKKQALNSHQIQSSLFDLQDEDIDQPVYDALMRIVQQVRLGAIQDLNSYVFSTMFDQFEQLGSKRAITAYKTSGATIIWE
>NZ_AP017932.1|WP_096585841.1|18035_18857_-|Fic-family-protein
MTKTQAYMDKYQFTVAENKRFARTNFTKLVHTSARFEGVNTTLPQTQTIMDGMSVAGVPVEDILTIVNLKRGWQYITDQNSSLTLTMEKQINKIVAAEDALVPGELRQGKGGVDLGSEDFFEPPLINEKQEQSFLQKILADPQTTTTDKALTVMYHNMRQQIFWDGNKRTATLSANKIMIDGGAGLINVPLDKWDQWNELIANYYRTNDMAKIKRWTYDNGIQGLQIRANLELKSVEDEIGKRIQEQLKDFAKHNPEIKPKNNPENKNDRPSY
>NZ_AP017932.1|WP_015474680.1|17767_18046_+|hypothetical-protein
MSNQYEKLVEQQARLKQKIDREDFKLRQSKYYENRQARKARSRRLIQKGALLEKYFQANNLSVEQTEELLKTFADYVNAHKPDKLKNDQPNN
>NZ_AP017932.1|WP_003555660.1|17517_17745_+|hypothetical-protein
MIGGIVMSQSNLEKQEAKLKALNQKIKDEKNKIEQRLGKQIISQANLDYANLSNDQIKLLAKQFSEFLKVKSVDH
>NZ_AP017932.1|WP_099769415.1|16368_17438_-|IS3-like-element-IS1520-family-transposase
MAIKYSNEFKESIVSLSQTGRSANSLAKEYNVSVSTVTKWIKQADPNNTKVLSSNERALIKENKRLKEELDIFKTSGGAHGKKLIIKGRALVLEVVNANLLAGHRITRILSVLKIPRSTYYDYLHWQPSRTERRRHLIKQEVLTAWLRYPMYGYPRLTILLNQQSDIHVSQRLVYQQMCELGIRSRMVKRINKPTTQTDYDQRPNLIKQLTDQSGILLTDITYIPLNHTWCYLASVYNPVTRRVIAYQLNTQMTKELATNVITQVMAQAVKPQIIHSDMGSQYTSDLFENTLSKYGIKHSYSRKGQPGDNARIESFHSILKREYVNFQDFKTIHEAIAGIDNYIRWYNSDRISLVA
>NZ_AP017932.1|WP_096585839.1|14768_15383_-|hypothetical-protein
MKVESWQGINGKLLHDDQKAIVVDDDQKLTELKQLQAILDQDGQPIDEVRQAMIKKTVKRQLKIEPLKLSGWFNRYQDSQNAKKTEKLVSDKPTHQYKQIKNEMTFFGESFLEGFLGFYGLKVDNALGRYERNLHVLETQELGQSEKEYYLATSENGRVKLATDPLPSQQIAEEQLDKFYQREPEQTQAEQVQLRSSEDEEKEE
>NZ_AP017932.1|WP_076648311.1|14431_14767_-|conjugal-transfer-protein
MKFSKMKALATTGATAIYLGLMNAQVVLAADGGEVKSKLTQAGKTIQGILTGLVVLVGICVALFIIIKRMPDADDPREKSEVYHAVGRVAGLVALAAAIIWLLPWVYSLFT
>NZ_AP017932.1|WP_014216295.1|14047_14410_-|hypothetical-protein
MKKGKEFIFPENVDKDYGIWKDYTLKDFGYAALAGLVGLIFIAIPPYGLILVLIKIVIVVLAMTIVMAILTIRPVAARKNIKVRDNFKLKRRYANGQKLFYLKPKKRGELNAFEEEQNRQ
>NZ_AP017932.1|WP_025085233.1|13419_14079_-|conjugal-transfer-protein
MRLKKNKTANKSARLDWDYQPPKINGGKETIDDMSLVVGMYGNYEVTKTGNLVGILEVSGINLDLLNETEQQDVFEDYGAFLMSTLGEGVDDTLQFLEPTIPVNMTAYLNGLKRRYLTLQKDHPEQQFKIQLMASYLDHFTKVQESKNMTTKQHLLIVKVPIKDKSVKSLSLAVTHLDEKIEQVKRDIENALTDFDVTAKVLTSQEVQEILKNLINFNG
>NZ_AP017932.1|WP_096585837.1|11392_13408_-|DUF87-domain-containing-protein
MSFGDKVIDLFMPTKKESQQNSEPAVNKQKPEVEDFTKLIDRDSLHSLFPFSWEQYPTYVQSGENFIRVLAIADYPKRVYGNWLSELKRKKGVIDIVQYIDSASNNSMITYYKKTIQNKEAQKLNTFDPYKKKILQNYIDSANMQLDKYLDNSTTFVYQHMLVYLRANSLVELDDLTENVKNTLIKLQMKPLVPVKATFQAFWSTMPINENLMGDYTYKESNTEVASSMFPFDDAEILDLKPRSDIEGVNKDTNSLIAVDMLDRNKTLNQNQVIIGTSGVGKTTYMIQKILRYAIQDYQIYIIDPENEYTKIVEALGGAVLHLTSNAKYKINPLQIFSEEILSADEAVTNLDLLVKDKIQRLKGFFEVLKTGITQVELAILDDVVKQAYVNSGVLKYSRLKEIKDDQWPTLSNVYDELEKLADKDADKFGRVKDFYYILGSYTRGSNSLFDGHTNVNLKGKIISFDLKPLQSEQEVQSAAYLNTFQYLWDEITKDRHNRKKLFVDEFHFLTLHKAAATFFHQAYKRFRKYNAGAIAGTQQIQDVIEGTTDTGQNIGEAIIGNSYTKVFFGLDGKGVDGVITKLRMTFSDKEKKLLERRRQGEALMIYGSQRAFMKVELTEEELRLIDPEAYQEKYNCETAIQPDYQKRVALTPSEVDALTTTEEEGGTLNE
>NZ_AP017932.1|WP_016265853.1|22102_22918_+|AAA-family-ATPase
MSSRVITFGNFKGGTGKTTTSTMVGIELARRNLKTLLVDLDPQGNATNLYLKTKENVDNEIVSFNKTLMAGIKDQDLSQTIINILPNLDVLPSSADFSLYPRFMETVSSDYNERVWYFSKLMKEFKEKYDYILIDIPPTISLITDSALYASDYCVIVLQTQERSLQGAEAFINYMQEQVIDTFKAPTLDLIGILPVLLKNGAPVDNSTLEVAKELFGSENIFDITIKNMERLKRYDVTGVMFKDQFDHAVQNVYEKVTTEMISRIGAIENG
>NZ_AP017932.1|WP_035145350.1|22910_23261_+|DUF5388-domain-containing-protein
MGSLLNSNRVKSNSLDRGKRIEPENSMSIKDLSNPGEQSKSSKIESVTYYANVRINNHIKNKAEALSIIGVAKSQKDAIDRALDSFVEQLSDDEKRSFKNQLATLEAKDVKMKSEK
>NZ_AP017932.1|WP_096585845.1|23855_24785_-|IS30-family-transposase
MSSITYSERIKIETFCELGLSNSQMGVRLNRSPSTISYELSRCQPYQAELAQTDAEYKQSRCGRKTKLSDELKQKIFNHLRLGWSPGMIAHEFKLATKSIYNWLNQGRIGFSLNDLPEHGVRQRRNVDQRSKYNQSLGRSIEQRPMMINQRNRIGDFELDTVVGPRGHSKAVLLTLIDRKSRFLWAYRLKDRTTATVNEALNKFLATFNGPVHSFTVDRGTEFSGLVSLESQYGIKTYYCHAYTPAERGSNERFNRNLRYFYLKGTRFEHISAQDLTTTLLQINQRPLKILDWQTPYQVMLTNLSKNSD
>NZ_AP017932.1|WP_016265840.1|24925_25876_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MSYKTINWDVIEDELDEYVWDKATAQYWLDTRVPVSNDLRDWRTLSGTEKSVINRVVGGLALLDTLQSEEGVDVLRPDVRTRKEAAVLNDFLMMESIHAKSYGTILTSLNDQATVDEVFKWMNNNPRMQYKAKRINDIYQTGNNLEKKVASVFLEGILYYTNFFTPLWYRGNNKLANLSEVIKLVIRDESVHGTYLGYKFQLGYNELSATEQKTFKKWMDELLDDLLENEFAFTEEVYAPIGLAEDVKQFVHYNANKALQNMGFESRFPNAEIKDINPIVMNGISTETANHDFFSQVGAGYLMGNAEAMSSGDYDF
>NZ_AP017932.1|WP_076648347.1|25890_26817_-|ribonucleotide-diphosphate-reductase-subunit-beta
MDYLYYKAINWDDIKDNFDKYMWERLTTNFWLDIRIPITNDQTDWQQLSDTQQQAITRMLAGTSMLAVYQSEVGTPAIRHDRRTQQEESVLNTITFMKSVHAKSCTTIFRALIPGNDGGSFTWADDNANLQAEIDQLAQTSTSDMALQKKALFILTETGLSFGKYWTILQTQDLVNTYQMLANILRGSALFSAYIGYKFRLRFEELTVSDQTELQYWINTQFDQLMQTEKDFLEANLDDATEAINLASYGANHALMSLGFNAVYEVQPSSLVAQLKELMIDQNQFLQQVTAANNESDTEKMTDNDYDF
>NZ_AP017932.1|WP_025016512.1|26923_29071_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MENTYFYLNNLVNIPSNGEIPLHYDQEALKAYFEETVKPKTKQFDSLNAKLNYLVDEDYIDPSILEQYSHKFVQSLFDQMRDHHFRFRSFLGAYKFYTQYAMKTNDGQKFLEDFVDRVVFNALYLANGDEQLANDVADELISQRYQPATPTFLNAGKKRRGEMVSCFLIDVADSMLSIGRGVNSALQLSRIGGGVGVNLSNLRASGDSIKQISNASSGVVPVMKLLEDSFSYSNQLGQRNGAGVVYLNVFHPDILHFLDTKKENADEKIRVKTLSLGLIVPDKYYELLKTNEPMYLFSPYDVEREYRTPFAYIDITKEYNNMVANPNIKKSVFNARKLEQKISQLQQESGYPYILNIDTANQTNPVDGKIIMSNLCSEILQPQEPSKLDDDLSYKTIGTDISCNLGSTNIMNMIDSPDFGHSVEVAVRALTLVTDTTDVKEVPTVKHGNELYHTIGLGAMGLHTALARHQIEYGSPEALEFTDAYFLALNYYSLVTSNRIARERHETFAKFDQSKYADGSYFDQYLNADFKFKSTKVAKIFKNIKLPSVTDWKALKQAVITGGLYHRNRLAVAPNGSISYVNETSASLHPITQLVEQRQENKVGSIFYPAPYLSNETLPYYTPAYDIDQRKIIDTYAVAQKHIDQGMSLTLFMRSVLKPDLYEWKDNNNLKMTTRDLNRLRNYAWTKGIKSLYYIRTFTEDDEIKTANECESCMI
>NZ_AP017932.1|WP_076631995.1|29098_29557_-|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MNILYISLSGNTKYFISRLTTYFEKERHVRVSSINVKEHPEFTTLDQPFVTFLPAFIKGGNGVNNGYTEILTTILGDYLAYEGNYQHCYGIIGSGNRNFNKQFALTAKQYAKRFDFPYITDFELRGTVHDIPRIADAILTYRDQFCFQTTKE
>NZ_AP017932.1|WP_003587210.1|30556_31024_-|DNA-starvation/stationary-phase-protection-protein
MKYTKTKAVLNQLVADLSQMSMIIHQTHWYMRGPNFLKLHPLMDEFMEEIDSQLDVISERLIALDGSPYSTLKEMAENTKIQDWPGEWDKTTPERLAHLVDGYRYLEDLYQHGIEVSDVEKDFSTQDIFIGLKTAIEKKIWMIQAELGSAPEIDE
>NZ_AP017932.1|WP_096585852.1|31586_32417_+|GIY-YIG-nuclease-family-protein
MPNHIFINRESGNDNISIFYDEPSFVVIANKDDLTSIQLIDESKKPGIYILLGDDKRYIGQASNAIFNRLQQHYINKPWWNKLIFFGREDGHLSKAQLDLLERKIIEKMKRAEIELDNNTQGNQSYIDKLSQFSALSLLSKVERVLIDIANINLFASDDTEFDRVDPTPNNDTISILFGRQHYTGSSYRDVFIKLVSTLVLSSDIAKLTDLINSTEPNTVQIIGTLERVSGQGTKLTKAIDSSKYHVYVNFSKDALYKKIQILANLTNNKVTFERW
>NZ_AP017932.1|WP_096585854.1|32424_33015_+|site-specific-integrase
MVQQIVLPIKDSNVLKMVQDTLLDSFRAGRRNYTIFQVGKATLLRVSDVMTLKKSDVYNPDGSVKHTAFIHDKKTGKANTLYLKPVQQDLLKYHDWLVQENINSDWLFPSTAHPDRHITEKQFYKVMARVGDLLGINYLGTHTMRKTGAYRVYTQSNYNIGLVMHLLNHSSEAMTLTYLGLDQASRETMLDQIDFG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	NZ_AP017932	Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence	21897-21938	0	1.0
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	NZ_CP025207	Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence	34342-34383	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	NZ_AP017932	Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence	21959-22007	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	NZ_CP025207	Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence	34404-34452	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	NZ_CP022710	Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence	60855-60903	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	NZ_KF559312	Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence	45044-45092	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	NZ_LT960778	Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence	1369-1417	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	NZ_LT960782	Lactobacillus sakei strain J64 plasmid 2, complete sequence	1369-1417	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	NZ_LT907987	Lactobacillus sakei strain T332 plasmid p332A2, complete sequence	1369-1417	0	1.0
NZ_AP017932_1	1.2\|21959\|49\|NZ_AP017932\|PILER-CR	21959-22007	49	AP018700	Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome	35484-35532	0	1.0
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	NZ_KF559312	Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence	45113-45154	1	0.976
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	NZ_LT960778	Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence	1438-1479	1	0.976
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	NZ_LT907987	Lactobacillus sakei strain T332 plasmid p332A2, complete sequence	1438-1479	1	0.976
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	AP018700	Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome	35553-35594	1	0.976
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	NZ_CP022710	Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence	60793-60834	1	0.976
NZ_AP017932_1	1.1\|21897\|42\|NZ_AP017932\|PILER-CR	21897-21938	42	NZ_LT960782	Lactobacillus sakei strain J64 plasmid 2, complete sequence	1438-1479	2	0.952

1. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to NZ_AP017932 (Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence) position: , mismatch: 0, identity: 1.0

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggtacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******************************************

2. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to NZ_CP025207 (Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence) position: , mismatch: 0, identity: 1.0

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggtacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******************************************

3. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to NZ_AP017932 (Lactobacillus sakei strain LK-145 plasmid pLs145-a, complete sequence) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

4. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to NZ_CP025207 (Lactobacillus sakei strain WiKim0074 plasmid pLSW74_1, complete sequence) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

5. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to NZ_CP022710 (Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

6. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to NZ_KF559312 (Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

7. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to NZ_LT960778 (Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

8. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to NZ_LT960782 (Lactobacillus sakei strain J64 plasmid 2, complete sequence) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

9. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to NZ_LT907987 (Lactobacillus sakei strain T332 plasmid p332A2, complete sequence) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

10. spacer 1.2|21959|49|NZ_AP017932|PILER-CR matches to AP018700 (Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome) position: , mismatch: 0, identity: 1.0

tttacacataataatacctataaataagcaatacacaacttttaatact	CRISPR spacer
tttacacataataatacctataaataagcaatacacaacttttaatact	Protospacer
*************************************************

11. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to NZ_KF559312 (Lactobacillus sakei strain KCA311 plasmid pKCA54, complete sequence) position: , mismatch: 1, identity: 0.976

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******.***********************************

12. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to NZ_LT960778 (Lactobacillus sakei strain FLEC01 plasmid 2, complete sequence) position: , mismatch: 1, identity: 0.976

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******.***********************************

13. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to NZ_LT907987 (Lactobacillus sakei strain T332 plasmid p332A2, complete sequence) position: , mismatch: 1, identity: 0.976

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******.***********************************

14. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to AP018700 (Lactobacillus curvatus NFH-Km12 plasmid NFH-Km12_plasmid1 DNA, complete genome) position: , mismatch: 1, identity: 0.976

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******.***********************************

15. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to NZ_CP022710 (Lactobacillus sakei strain WiKim0063 plasmid pLBS01, complete sequence) position: , mismatch: 1, identity: 0.976

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
ggaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
******.***********************************

16. spacer 1.1|21897|42|NZ_AP017932|PILER-CR matches to NZ_LT960782 (Lactobacillus sakei strain J64 plasmid 2, complete sequence) position: , mismatch: 2, identity: 0.952

ggaaggtacgataaatattttgtttacttgtattaatgtaaa	CRISPR spacer
agaaggcacgataaatattttgtttacttgtattaatgtaaa	Protospacer
.*****.***********************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP017931_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP017931_1

1727685-1728091

Orphan

Consensus_repeat	Method
GTATCCCAATTCGAAACATCTAA	CRISPRCasFinder

5 spacers

csa3

The CRISPR arrays of NZ_AP017931_1

>merge|NZ_AP017931|1|1727685-1728091|CRISPRCasFinder
GTTTGCCACTTAGAAACGTCTAACTGCGTTAATCTTTGATCACCGCTGAACGTGTAAGACAACGATGTATTTTTGCCGAGCTGCCATTTTGAGACATCTAAGGTTTCAAGTCTTGAACATCCCGAAAAAGTATAAGCCATTGTCGTCACTTGGCTTGTATCCCAATTCGAAACATCTAATTCGGCAATACTAGTATTCAGAAAAGTACTACTTAAATTAGTAACGTGACTGGTATCCCAATTCGAAACATCTAAAACAGTAATGCCCGATTGTGAAAAGGTACTCCCCAGATTAGTCATTTTTGCCGTCTGCCATTTTGAAACATCTAAGTTCGTTAAGGCCGTACAATTGAAAAATGTGTTATTCATATTTTGAATATTAGAAGTGTCCCAATTCGTACTATTTAG

>NZ_AP017931|1|1|1727685-1728091|CRISPRCasFinder
GTTTGCCACTTAGAAACGTCTAA	CTGCGTTAATCTTTGATCACCGCTGAACGTGTAAGACAACGATGTATTTTTGCCG
AGCTGCCATTTTGAGACATCTAA	GGTTTCAAGTCTTGAACATCCCGAAAAAGTATAAGCCATTGTCGTCACTTGGCTT
GTATCCCAATTCGAAACATCTAA	TTCGGCAATACTAGTATTCAGAAAAGTACTACTTAAATTAGTAACGTGACTG
GTATCCCAATTCGAAACATCTAA	AACAGTAATGCCCGATTGTGAAAAGGTACTCCCCAGATTAGTCATTTTTGCC
GTCTGCCATTTTGAAACATCTAA	GTTCGTTAAGGCCGTACAATTGAAAAATGTGTTATTCATATTTTGAATATTAGAA
GTGTCCCAATTCGTACTATTTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP017931.1\|WP_025016095.1\|1717622_1718213_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_AP017931.1\|WP_096585620.1\|1733918_1736507_-\|RND-family-transporter	unknown	unknown	gnl\|CDD\|223964
NZ_AP017931.1\|WP_096585627.1\|1739489_1739840_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_AP017931.1\|WP_096585595.1\|1718648_1719638_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375451
NZ_AP017931.1\|WP_096585617.1\|1730256_1730874_+\|DUF1361-domain-containing-protein	unknown	unknown	gnl\|CDD\|369208
NZ_AP017931.1\|WP_172425595.1\|1739912_1742750_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_AP017931.1\|WP_096585625.1\|1738813_1739422_-\|cadmium-resistance-transporter	unknown	unknown	gnl\|CDD\|226750
NZ_AP017931.1\|WP_016264496.1\|1730943_1731480_-\|DUF308-domain-containing-protein	unknown	unknown	gnl\|CDD\|225786
NZ_AP017931.1\|WP_016264495.1\|1731514_1733638_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_AP017931.1\|WP_096585592.1\|1716469_1717534_-\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_AP017931.1\|WP_096585604.1\|1722564_1723128_-\|DUF916-domain-containing-protein	unknown	unknown	gnl\|CDD\|368712
NZ_AP017931.1\|WP_096585633.1\|1744424_1745291_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NZ_AP017931.1\|WP_025016096.1\|1718214_1718517_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|366278
NZ_AP017931.1\|WP_096585614.1\|1729068_1730061_-\|choloylglycine-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238303
NZ_AP017931.1\|WP_096585608.1\|1723219_1724077_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_AP017931.1\|WP_096585601.1\|1721798_1722083_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197670
NZ_AP017931.1\|WP_025016102.1\|1724295_1725333_-\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_AP017931.1\|WP_096585598.1\|1719710_1721567_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375450
NZ_AP017931.1\|WP_035145632.1\|1722075_1722510_-\|DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_AP017931.1\|WP_096585623.1\|1736613_1737099_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_AP017931.1\|WP_025016095.1\|1717622_1718213_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	2.10215e-31
NZ_AP017931.1\|WP_096585620.1\|1733918_1736507_-\|RND-family-transporter	gnl\|CDD\|223964	COG1033, COG1033, Predicted exporters of the RND superfamily [General function prediction only].	5.71144e-109
NZ_AP017931.1\|WP_096585627.1\|1739489_1739840_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.52764e-14
NZ_AP017931.1\|WP_096585595.1\|1718648_1719638_-\|hypothetical-protein	gnl\|CDD\|375451	pfam17966, Mub_B2, Mub B2-like domain. This entry corresponds to the Mub B2 domain. This domain is related to the Mub B1 domain pfam17965. This domain may be involved in mucin binding. This domain is often found associated with the related pfam17965 in bacterial cell surface proteins.	4.87272e-17
NZ_AP017931.1\|WP_096585617.1\|1730256_1730874_+\|DUF1361-domain-containing-protein	gnl\|CDD\|369208	pfam07099, DUF1361, Protein of unknown function (DUF1361). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins.	1.63669e-27
NZ_AP017931.1\|WP_172425595.1\|1739912_1742750_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	4.92154e-07
NZ_AP017931.1\|WP_096585625.1\|1738813_1739422_-\|cadmium-resistance-transporter	gnl\|CDD\|226750	COG4300, CadD, Predicted permease, cadmium resistance protein [Inorganic ion transport and metabolism].	4.75149e-53
NZ_AP017931.1\|WP_016264496.1\|1730943_1731480_-\|DUF308-domain-containing-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	4.18527e-14
NZ_AP017931.1\|WP_016264495.1\|1731514_1733638_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_AP017931.1\|WP_096585592.1\|1716469_1717534_-\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	1.06645e-45
NZ_AP017931.1\|WP_096585604.1\|1722564_1723128_-\|DUF916-domain-containing-protein	gnl\|CDD\|368712	pfam06030, DUF916, Bacterial protein of unknown function (DUF916). This family consists of several hypothetical bacterial proteins of unknown function.	6.92957e-31
NZ_AP017931.1\|WP_096585633.1\|1744424_1745291_-\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	6.13393e-159
NZ_AP017931.1\|WP_025016096.1\|1718214_1718517_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|366278	pfam00746, Gram_pos_anchor, LPXTG cell wall anchor motif.	6.9213e-05
NZ_AP017931.1\|WP_096585614.1\|1729068_1730061_-\|choloylglycine-hydrolase-family-protein	gnl\|CDD\|238303	cd00542, Ntn_PVA, Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins. PVA has an N-terminal nucleophilic cysteine, as do other members of the Ntn hydrolase family to which PVA belongs. This nucleophilic cysteine is exposed by post-translational prossessing of the PVA precursor. PVA forms a homotetramer.	3.28079e-148
NZ_AP017931.1\|WP_096585608.1\|1723219_1724077_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.78377e-05
NZ_AP017931.1\|WP_096585601.1\|1721798_1722083_-\|hypothetical-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.65031e-05
NZ_AP017931.1\|WP_025016102.1\|1724295_1725333_-\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	5.18202e-43
NZ_AP017931.1\|WP_096585598.1\|1719710_1721567_-\|hypothetical-protein	gnl\|CDD\|375450	pfam17965, MucBP_2, Mucin binding domain. This domain is found in bacterial cell surface proteins that interact with mucins. The archetypal member of this family is the Mub-R5 B1 domain. This domain has a beta-grasp fold.	5.40364e-07
NZ_AP017931.1\|WP_035145632.1\|1722075_1722510_-\|DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	3.75158e-16
NZ_AP017931.1\|WP_096585623.1\|1736613_1737099_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.39588e-06

>NZ_AP017931.1|WP_025016102.1|1724295_1725333_-|DUF916-and-DUF3324-domain-containing-protein
MRLRKWTTGLAVGLFGWLLLASNQPVSAAQEHIDFEVEKVKSNRQVDQENRFFDLGIEPGKKETIQVLVHNFSDKNIKVHSEIDNSLTQQGGGIIYRPTKDGIIKETSHTLMDVAKVHRADRVITLGPNEVKKVSATITMPSEQTKGMIYGAWHFIEYGQKETDNHSNVSGSYAYNMGIVLRGKPYEIYPELKYQGVNPTVRNGHPALGIQLNNTKPMAIKNAKVKAVVYKNGFFKDKRVYETDSVDVAPNSQWTVPISWAFDRLKPGRYNISISVKGNSYWNQLPMSWHFRKKITINQQQADKINQASVKKPVNKWAYVATASGILMLVSFWFVYRVLKLTRGL
>NZ_AP017931.1|WP_096585608.1|1723219_1724077_-|WxL-domain-containing-protein
MKFTKLTSTVLTASTLLAILAPATIASAATPKDDAAANGGTKLPMTDTTDAGISFGDTHDNGNSGYLRLQMVPKTLDFGNHAKYDAAHTNFDATGANLGVVGNDTHASYDQQDSNKTETLTTSDANLKAVQGTAWATVVDKQVENPELAAATPKANTAGDWKLTVSADGDGLKAGGHTIADANLVFGNTKYGRTADIYGLTNQDQDNDGYTAAGTTDATYAKSVSLNLSTPNEEKVVGTAAKDAGDGANVFGWNPSDIRLALNGSNDVATGEYHAGLTWTLNTTI
>NZ_AP017931.1|WP_096585604.1|1722564_1723128_-|DUF916-domain-containing-protein
MFKRLNMLWFCLILVDLLTVQTSNPVFAKSEGLAIPAEPKATFMLRPELPKDNLGYKRLGYFNLKLKRGQQRTVFLKVFNPTAQPLTIYGRVKDATTNDNATVDYLGANPIDRQLLKQPGSQLVKVPRATKLQPNETKRLKVTIQAPAKGFKGQKATAINLSTNQLAKHNAVENHYVYAITLILNGR
>NZ_AP017931.1|WP_035145632.1|1722075_1722510_-|DUF3324-domain-containing-protein
MKQKRAAISVAIANPNPAYLKSATVKVDLQNQQWSLIRYQDQKSNRKIAPNSRFYEDVPLGGKRLVAGVYRMTLTIKTAHQQQIIHKNVAISKGQARYINQNNDQYLKYRNLLLLGGFVMVLMGVIGGYRILKVKHMKRDEHDD
>NZ_AP017931.1|WP_096585601.1|1721798_1722083_-|hypothetical-protein
MIKSEKNQYLEGYQLLTRLENGLDTIAKRHGVSFSQYLILKQIVENDCNEPSLLAKAFAISRPAMSRKLMVLFRNGKIKKLYNLKDEDQRITSL
>NZ_AP017931.1|WP_096585598.1|1719710_1721567_-|hypothetical-protein
MNREKGFRKVLLFGLALYVVGFGLGQDVTHSYATEASSDATLTSQLSSDSESTSSQSSSETLASETPKIAPETKGESTNPVKVMPSLAKTQTPVTQKVARAATTYKIQDLIDQGGVKTTVTWDIYSQSEDDISQGYTGTYYPKVIKFSVLPNNVLQPGDTISFSVLRYTGKLSGQGPVTMASVSLRELGQYDGKSLVLGSEYVPDKAVDASSDLPKSSGGVATLTNETTPDYTAAYAGSTINGTKSSVTVIPATHFNGFQVTNAAVGSDKKGTLTLSGYTKDQTYFQSALDGTPNLKGVPTANYVRIYRIDKESAQNINKVSFDLKTYMPALMPDGQHMAAKAGTTGPMLFIKAPAAVPINNSGSVAADATDDEIIAKTSPQTYGVLHNSDGSMTLYLNYGNLTRPYELPVDTITKGVMNNSWDGTQEGLDYALNRLSNNNYSALATSTYFTMNISFNDPSIENTVQATYKDTLNNTETINQPSSPPSASTDGQTTIKVHYADQNGKYIKPIETHYGWPDTDKLQITTQDLTIPGYTLDKSNLPKGADPDTGALTLSYPKEAGKVDDILYRFIQNKQKIDVTYVDDTTGKQLATDTMSGVVDENSKYNTQTKLAAYEK
>NZ_AP017931.1|WP_096585595.1|1718648_1719638_-|hypothetical-protein
MHLKHAIKAAPDESKQVKRTIHYRYQSNKQAAPDVVDKITFTRHDQIDQVTNQSIGFTKWVSTEGTTTFAKQTSPVIKGYTADQLTVPAVENITQDSADITATVTYTGQAQKATVTYQRSDNQAVIQADQLTGVSGQISDYRTDATLAALADKGYTVADNPYPSDGLVFDDDVAVDQNVTVLLNYNPYYNRVYFKSVPSEMDFGQHTLASTTESYQPTVNQALSIQDERALGSKWTLKAALVQPFTGDTQKAPLEGDLTYQRANQLPTMITAQSTIIATTTTTSHDPVDISGQWQNQLGPQLVVPVGGALIDQYAAQVEWTLEDGVANE
>NZ_AP017931.1|WP_025016096.1|1718214_1718517_-|LPXTG-cell-wall-anchor-domain-containing-protein
MRWLKNKSKFVVLMLIIGSGLIVVNPTHTSANAQTATKSVARVGFYETGQPHKQAPIQTETKQQARLPQTGTSSVGLSTIVGIVLLIGSLGLFKQRRGNF
>NZ_AP017931.1|WP_025016095.1|1717622_1718213_-|WxL-domain-containing-protein
MKKFMMSTLLLSGMLSISMGQVHAADTDSHDTTGKVGFKAPDTGGLTMTNTDALNIDFGSNPISADDKTYSNINDAKATVQDIRGTAAGWTLTVAQNAQFKTSDNTELTGAQITIKTPTLDTASTATATVDQSLVLTTDNTAHKIMGAAAGEGNGTAIADMNTGSVTLDVPGKTVKVAKDYTTMLTWNLADAPADN
>NZ_AP017931.1|WP_096585592.1|1716469_1717534_-|DUF916-and-DUF3324-domain-containing-protein
MKRKYRLMIWGLVLFMSVFVNVKVADAANNAGFEVIPVASKQQLNQKVTYFDLKLAPNQATTVTVNVKSTSQTPITVETSVAKATTNTNGVVEYKAFKQNKSWGLPANIEKVVTTDQNKIQLQPGEVKPVAYQIKMPKAAFDGELVGGLNFVKKVTDDKVKTNSSMGVKNQYAYTIAMVLHGQQELTKNKMSLGKITTRQINNRNVISIPLNNQTAAFLNKVTTKVTIKKQGQAKAVYTQKTADGQMAPNSVYELPVRIGETAFRPGRYTAQVVVTSKQQHWQFTKDFTITKKQARHYNQKAVIKEDDSWLGLSLIITGIVLLLILIIVIYWRKQRRIKLLESELAASKRDSNQ
>NZ_AP017931.1|WP_096585614.1|1729068_1730061_-|choloylglycine-hydrolase-family-protein
MCTSLTYSTVDGHHFLARTMDFSFELNGNPLFLPRQHQWQPVLEKQAIQNQYALMGAGAKLGDQYLVADGFNEHGLGCAELYFAHAAVYEPQPVPNKLNLVAEEFIVWVLGNHQTLEEVAADLDNVRIIESDQGVMGANQPLHWILSDRSGKTMVIEPRGNGLQLIDDPVGVMTNTPDLDWHIKNLSNYLNLQPQPFMERPFGNYQAGLFSQGTGTQALPGSYTPPDRFVRAAYSRQYMPEANNVAEGVNHTLHILDNVTIPKGVNIGSGGSSDYTQYQGISGLNNLAYYMVNYDNRHVYQTNLTTDLIENQKEPLIYHLPQGQQNTILN
>NZ_AP017931.1|WP_096585617.1|1730256_1730874_+|DUF1361-domain-containing-protein
MSKKVLTIHAIILLFFALILLYQSRFAFLIWNIILALIPFDLSLLGRLFKNSRWRYLIGVVWLLFFPNALYMITDFSHLSSIGVGLSTAFQFVEYAILAGGIFIGVTLGLTSLFILYPLFIPNHQRLINQVATFGVLSVCSSVAIYIGRFLRINSWDVFYQLHTTIASVLSILNQSDFWIFVVAFSILQLILMLMGYQLAQLDEM
>NZ_AP017931.1|WP_016264496.1|1730943_1731480_-|DUF308-domain-containing-protein
MLSKNISNKLRQATGVNGLLSLILGLLILFLPGQSAMGVTVMVGVVFIIIGLFDILSIFKEVDENTWVRLGHLLLGLLYLIVGIFVCVNLAASATYLFLLVGIFVGITWLVEGFVELGTVRLAVSKGWTIFSAVLSIVAGIILLMTPLYGAVMLWTLLGAILVVLGIFKVAHYLAWQK
>NZ_AP017931.1|WP_016264495.1|1731514_1733638_-|ATP-dependent-Clp-protease-ATP-binding-subunit
MANMYGNDPFFNNDMDDIFNQVFRRMGNSESARYVINGRELSPDEFAQYRATGKLPNREKEIEIKQNGEHALKKGGILEKLGRNLTQEARDGLLDPVIGRYNEIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQEIVAGKVPETIKDKEIYSIDLSSLEAGTQYRGSFEENIKNLIKEVKAAGNVILFFDEIHQILGIGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEYRNTILKNAALARRFNDVLVNEPSAADTVKILQGIKGLYEKHHHIELPDDVLKAAVDYSVQYIPQRTLPDKAIDLLDMTAAHLAAKRPETDKAKLAAELKQLEADKAEAVEAENYQAAEDLKVRIEKIKTQLENNDQHAAVMIATVDDIAQSVERLTGIPVAKMGSNDIQRLKNLGQRLKDKVIGQDEAVEMVARAIRRNRAGFSEGNQPIGSFLFVGPTGVGKTELAKQLALDMFGNKEAIIRLDMSEYADRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLFDEIEKADPQVLTLLLQVMDDGRLTDGQGNVIDFKNTVIIATSNAGFGNEKLTMNDQEDAKLLDKLAPYFRPEFLNRFNGIVEFTHLTKADLSQIVDLMLTNVEQTLAKKELTLVVSKEAKDWLMEEGYDEAMGARPLRRVIEQQIRDKVTDFYLDHADVKDLKADLVDDQIVIQAVDSEN
>NZ_AP017931.1|WP_096585620.1|1733918_1736507_-|RND-family-transporter
MTNRFFTKISQIIHNNPIKVIIAVVLLTIGLAFGLPNIQMNMGNEVFVDTNSQVYKDTKTYQENFGGGSAYVLISGDQDQIVTHTTMKKVAALENKINKVDHIRSSTSVVSLLNQELESNAASTMGGNAKGSDKLQKDLMANLTTSQKTALQTKLQASLTPEQQQQMGQYGLSLLTSQQKMAAAQAGNQSPATLMKQLDKTQQVKVQQYLFTILNQDQQQMLQKQMLADLPKVEHMSTALLRDLMLDSKGHVRSQLSALLPKNGQNLLIMANMAAKTDMTTNVQVVHDVWHDIKQAGFQSDLKVRLAENPVIMGGIQPLVMKTMATMLVLAVIIMVVVLFVVFPVRRRLLSLCYVLLGLIWTFGIMGWLHIDLTLATMATLPIIIGLGIDFGVQFHNRYEEEFHKSASGEQATKRAIKTMGPAVGVALIVMVFSFLTMFLSKAPMMQQFGLTLAIGVAAAYVVEFLLMFSSFALLDRKSKTTAKPQSAPKTSGLAKALRKYAQFVIKHAKILTLVGIILAATGFSVEGRIPIETNLTKLIPQDMQALKDTKYLQKQVGSTTYMTYLVKADDVRDKAVLAKTTQFANRENHKYQDIVGVTTLDSTYRQMGGTPKQQTQTEINEGIKTIPGTIRGTMLSKNNHYTMVQFKVDRSLTTGQQRTLMHHINRDLKHHATTLDVHPAGDSVMMLVGVGNMVVNHTLIILAGLAIIAVILIAVYRDLKMALLPILPIAIVLGLSPLTLHLLGESYNPLTIALSSLVLGVGTEFTILILERFKEEQQLGKSTEEAIIVAVTNVGQAITASGLTVIGGFAALIFTSFPVLSSFGLITVLDTLYSLIAALTILPAMIVISDKWFGGSKNKAK
>NZ_AP017931.1|WP_096585623.1|1736613_1737099_+|TetR/AcrR-family-transcriptional-regulator
MTKGEQTRQKIIEATVALMLSDTRASVSHIIKQTHVSRTTFYRHFPSLGDAILAATLTRFPTSYQSITDPAELLELVINTLDQDLAFFVHFSVYKEEFDFLFKQLFFKVANNVQITLLDRTPVNDELVYRAISGIVAGWMTNTTTIKAADVKGFIQQILNL
>NZ_AP017931.1|WP_096585625.1|1738813_1739422_-|cadmium-resistance-transporter
MQTAILTGITAYISTSIDYLIILMVIFGSVNRKERWLVYWGDLLGTSVLVAASLVMAFILGFVPQEWLLGLLGIIPVLMGLRLLISGESDDDEVVESQMKKRRNIIMNVAIITIATCGADNIGIYVPIFAQSTVQTLAVILITFFFMLSLFCYVGYLLIKIPKVAEILERYGMYITAIVYIGLGLYIMFESGTVQHLVKMLG
>NZ_AP017931.1|WP_096585627.1|1739489_1739840_+|winged-helix-turn-helix-transcriptional-regulator
MLKNEAIPLNTVNLIPERNLEESKRILKLLSNPTRLQLLHILAQRECNVGELGELLQIEQSIVSHQLAMLRDHQLVSATKHGKLSYYKLDDPHILDISGEVLEHADHVVRGKQHGQ
>NZ_AP017931.1|WP_172425595.1|1739912_1742750_-|WxL-domain-containing-protein
MPTDSKTSSHSEQSVSTQSKSESKSESKMTSSEKSSSETTTQSSSSHRDKSVIQNQSRDTIMPTATIDDGVTGWQPAKQTTIASIDIDKAANKSLNYTFGNSDGTLKFDQGNGGIITNNMPPRMNVFIKDNGKIVESSFKSTSGMGGSYDYSLLTTRSSTAPTIKTTSTSAQGSLTGVQYYQAKDAKGQTILKMVGQYTTIVGRVPSFTLEYLLRPSLEKPSVQQELYIYNATSAAIDGGIFFAKDTSLNGNDGVPVSAQGNNAGMYIADGKYKLFLNMGVEDGPAKFNAMNYHRNGGYNLSDYAMNDYSPANFDGAGIEVKNLKEGATVYSGSDSAYSAKWNWQTFQPDTVYHFRNDLGIATAGLVVPEAAENYKNKTTSDQKNHVQDNITIEMKAHNLGYSSEWKDINVTSKIPDELDIDPSTIKVTLNNGDQVAIDASKYNQTTRMLTVRLLKNLSENEWSSISFDAKINGKASGKTINSSMVAKTESGTGNFDTATANTKIPVEVEPVEIEKKVLNETEKETTYQKATVGHVNDVLDYQVKLTVSSNGADMSNGVLADDLAKEGLKLVPGSVKLTYSDKTVETPADVKQINLKKMTPGQNVVLTYKAKDKEGVVIGTVLKNIVLYSGEQANQGVMNGQADASVTIEKTKNSDVHFSYIDRETGQQITNEVVATGPIDAKISALKATDISDGQDPNKIRPAYIEGYTPVDFTTATDLNAAVYADIKDVDPVIEEKSVTYTFRYEKTRLAITALPSKLNFGKFDDTQSERTFYLPAQIEKPTDEKTPYGIEISDYWGIKGWTLSVAQEQQFHGSATIDSKEQAVELSGAQLQFNNATLSTNTEGNKSVSNSQDKVVTKSNFNLVPGAEPLELVEYERKGQYLNQDGDNKGGVSYDIPGYSVHKYQFGDARTADYSIGLHVPETTERYRTEYTSTLKWHLTAAP
>NZ_AP017931.1|WP_096585633.1|1744424_1745291_-|aldo/keto-reductase
MDMVQLNNGVQMPQLGFGVFQMTDLAECKQAVVDAIASGYRLIDTAAAYHNEAAVGRAIKRSGVAREELFITSKLWVSDASYERAKKGIDQSLQNLGVDYLDLYLLHQPFGDVIGAWRALEEAYKAGKIRAIGVSNFYADQLKNLILSTNVKPVINQIEVNPWYQEHSEVAFAQAEEIQVEAWAPFAEGKHNIFTDDRIAAIGSRYGKSNGQVILRWLLQRGIVVIPKSVHQNRMAENINVFDFELTTAEMATMNDLDKGESQFFDHRDPAAIEQIFGTSLAALKENK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

443650 : 532256

Lactobacillus_phage(32.0%)

capsid,holin,terminase,integrase,transposase,portal,tail,tRNA,protease,head

attL 450293:450316|attR 532362:532385

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065825252.1\|443650_444580_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW47	unidentified_phage	1.8e-25	33.3
WP_096585790.1\|445307_447305_+	LysM peptidoglycan-binding domain-containing protein	Q9ZXE4	Bacillus_phage	3.1e-19	41.7
WP_096584412.1\|447638_450062_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	69.9
450293:450316	attL	NA	NA	NA	NA
WP_011375127.1\|450661_452014_+	amino acid permease	NA	NA	NA	NA
WP_011375126.1\|452271_452646_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011375125.1\|452795_453974_+	MFS transporter	NA	NA	NA	NA
WP_011375124.1\|454521_456159_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_011375123.1\|456155_456875_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_011375122.1\|456902_457736_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_096584415.1\|458092_459205_-\|integrase	site-specific integrase	A0A0P0IXL3	Lactobacillus_phage	2.4e-69	41.6
WP_148664861.1\|459383_460268_-	hypothetical protein	NA	NA	NA	NA
WP_096584421.1\|460435_461056_-	LexA family transcriptional regulator	A0A1B2APZ3	Phage_Wrath	3.1e-42	65.1
WP_096585791.1\|461214_461445_+	helix-turn-helix transcriptional regulator	E9LUS9	Lactobacillus_phage	2.0e-15	56.6
WP_096584424.1\|461461_462238_+	phage antirepressor KilAC domain-containing protein	A0A1Q1PVU2	Staphylococcus_phage	7.2e-73	54.3
WP_096584427.1\|462269_462581_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_096584430.1\|462814_463015_+	hypothetical protein	NA	NA	NA	NA
WP_096584433.1\|463108_463300_+	hypothetical protein	NA	NA	NA	NA
WP_096584436.1\|463299_463644_+	siphovirus Gp157 family protein	A0A2H4JBT9	uncultured_Caudovirales_phage	1.5e-06	48.6
WP_172425578.1\|463601_463784_+	siphovirus Gp157 family protein	NA	NA	NA	NA
WP_096584442.1\|463774_465154_+	DEAD/DEAH box helicase	A0A0A1ENT0	Lactobacillus_phage	8.7e-162	63.1
WP_096584445.1\|465150_465876_+	AAA family ATPase	A0A2P0ZLB2	Lactobacillus_phage	1.0e-65	60.3
WP_056966820.1\|465878_466391_+	hypothetical protein	A0A0A1ELK1	Lactobacillus_phage	1.2e-23	35.4
WP_096584448.1\|466462_467305_+	bifunctional DNA primase/polymerase	A0A1B0Y4T1	Lactobacillus_phage	8.4e-83	60.3
WP_096584451.1\|467252_468488_+	helicase	A0A1B0Y896	Lactobacillus_phage	1.6e-130	56.4
WP_096584453.1\|468782_469103_+	VRR-NUC domain-containing protein	A0A0M7RDN7	Lactobacillus_phage	6.9e-38	71.7
WP_096584455.1\|469108_469297_+	hypothetical protein	NA	NA	NA	NA
WP_096584457.1\|469293_470001_+	hypothetical protein	NA	NA	NA	NA
WP_096584459.1\|470020_470416_+	hypothetical protein	C9E2N9	Enterococcus_phage	2.3e-06	39.0
WP_096584461.1\|470420_470609_+	hypothetical protein	NA	NA	NA	NA
WP_172425579.1\|470651_470801_+	hypothetical protein	NA	NA	NA	NA
WP_172425566.1\|470866_471142_+	hypothetical protein	Q9AZZ8	Lactococcus_phage	1.9e-07	50.0
WP_096584463.1\|471252_471450_+	hypothetical protein	NA	NA	NA	NA
WP_096584465.1\|471463_471646_+	hypothetical protein	NA	NA	NA	NA
WP_096584467.1\|471924_472272_+	DUF1642 domain-containing protein	C1KFT5	Lactobacillus_virus	9.2e-20	47.4
WP_172425580.1\|472268_472418_+	hypothetical protein	NA	NA	NA	NA
WP_096584469.1\|472401_472770_+	hypothetical protein	U5U4M8	Lactobacillus_phage	1.3e-11	36.1
WP_096584471.1\|472918_473170_+	hypothetical protein	A0A291I9M4	Lactobacillus_phage	4.8e-18	59.0
WP_172425581.1\|473169_473328_+	hypothetical protein	NA	NA	NA	NA
WP_056948437.1\|473308_473722_+	hypothetical protein	E9LUP5	Lactobacillus_phage	2.9e-20	40.0
WP_096584475.1\|474026_474389_+	hypothetical protein	NA	NA	NA	NA
WP_099769415.1\|474442_475511_+\|transposase	IS3-like element IS1520 family transposase	Q6J1X2	Lactobacillus_phage	6.3e-27	34.9
WP_096584477.1\|475682_476138_+	hypothetical protein	NA	NA	NA	NA
WP_096584479.1\|476524_476932_+	hypothetical protein	NA	NA	NA	NA
WP_096584481.1\|476935_477187_+	hypothetical protein	NA	NA	NA	NA
WP_096584483.1\|477273_477639_+	HNH endonuclease	A0A0M4RCH0	Enterococcus_phage	2.3e-21	40.9
WP_096584485.1\|477762_478224_+\|terminase	phage terminase small subunit P27 family	M1PKP2	Streptococcus_phage	2.8e-24	44.4
WP_096584487.1\|478216_479926_+\|terminase	terminase large subunit	A0A249XUH4	Enterococcus_phage	3.0e-119	39.8
WP_172425582.1\|479937_480102_+	hypothetical protein	NA	NA	NA	NA
WP_096584489.1\|480106_481297_+\|portal	phage portal protein	A0A2H4JA65	uncultured_Caudovirales_phage	1.8e-59	35.2
WP_096585793.1\|481277_481820_+\|head,protease	HK97 family phage prohead protease	A0A0M4R4P2	Enterococcus_phage	6.2e-39	48.6
WP_096584491.1\|481855_482980_+\|capsid	phage major capsid protein	D2KRA9	Lactobacillus_phage	4.9e-70	42.8
WP_096584493.1\|483012_483231_+	Ig domain-containing protein	A0A1D6Z291	Staphylococcus_phage	1.7e-08	55.6
WP_096584495.1\|483244_483574_+\|head,tail	phage gp6-like head-tail connector protein	Q9ZXF3	Bacillus_phage	1.3e-07	33.7
WP_172425583.1\|483566_483866_+\|head	phage head closure protein	NA	NA	NA	NA
WP_096584501.1\|483862_484219_+	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	3.5e-14	35.6
WP_096584503.1\|484211_484634_+	hypothetical protein	E9LUI8	Lactobacillus_phage	1.5e-19	38.9
WP_096584506.1\|484620_485205_+\|tail	phage tail protein	M1PRQ7	Streptococcus_phage	5.7e-46	49.5
WP_096584509.1\|485275_485578_+	hypothetical protein	NA	NA	NA	NA
WP_172425584.1\|485628_485781_+	hypothetical protein	NA	NA	NA	NA
WP_096584512.1\|485796_490116_+\|tail	phage tail tape measure protein	A0A2D1GPD5	Lactobacillus_phage	3.0e-200	51.8
WP_085845083.1\|490108_490822_+	hypothetical protein	A0A1B2APY0	Phage_Wrath	1.0e-41	37.2
WP_096584516.1\|490821_492336_+\|tail	phage tail protein	A0A1B2APX2	Phage_Wrath	1.0e-62	33.8
WP_096584520.1\|492335_493991_+	hypothetical protein	G2J5Q9	Lactobacillus_virus	3.2e-25	32.9
WP_096585794.1\|494118_494385_+	hypothetical protein	NA	NA	NA	NA
WP_096584523.1\|494381_494591_+\|holin	holin	A0A2H4IZQ3	uncultured_Caudovirales_phage	1.3e-05	47.5
WP_096584526.1\|494587_495499_+	N-acetylmuramoyl-L-alanine amidase	Q9MCC8	Lactobacillus_phage	2.2e-57	63.0
WP_096584529.1\|495761_496208_+	SocA family protein	A0A0N9SGM1	Paenibacillus_phage	2.0e-22	40.1
WP_096584532.1\|496208_496598_+	hypothetical protein	NA	NA	NA	NA
WP_096584535.1\|496639_496894_-	hypothetical protein	NA	NA	NA	NA
WP_011375121.1\|497236_497437_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_096584538.1\|497467_499708_+	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.9e-95	34.9
WP_096584541.1\|499835_500624_+	HAD family hydrolase	NA	NA	NA	NA
WP_096584544.1\|500577_501516_-	alpha/beta hydrolase	O11456	Ectromelia_virus	8.3e-15	26.3
WP_096584547.1\|501697_503290_-	APC family permease	NA	NA	NA	NA
WP_011375116.1\|503644_503851_-	hypothetical protein	NA	NA	NA	NA
WP_096584550.1\|504302_506243_+	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	2.6e-34	41.2
WP_056948128.1\|506506_508198_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	3.9e-79	33.5
WP_056948130.1\|508588_509350_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_056947380.1\|509478_509865_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_056947382.1\|509854_510742_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.2e-08	25.4
WP_096584553.1\|510759_511917_+	hypothetical protein	NA	NA	NA	NA
WP_011375108.1\|512092_513526_-	amino acid permease	NA	NA	NA	NA
WP_172425605.1\|513699_515259_+	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_011375106.1\|515338_515575_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_011375105.1\|515687_516446_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_096584560.1\|516461_518816_+	ribonuclease R	Q0GXV6	Lactococcus_phage	4.7e-91	41.0
WP_025016036.1\|518824_519295_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.0e-46	58.3
WP_096584563.1\|520780_521671_+	hypothetical protein	NA	NA	NA	NA
WP_076632110.1\|522139_522631_+	winged helix DNA-binding protein	NA	NA	NA	NA
WP_096584566.1\|522753_525414_+	DNA polymerase I	B6V2J7	Bacillus_phage	5.2e-46	32.4
WP_056947267.1\|525425_526262_+	DNA-formamidopyrimidine glycosylase	F8WPX6	Bacillus_phage	9.0e-29	32.3
WP_076632108.1\|526261_526870_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_016265454.1\|527177_527651_+	transcriptional repressor NrdR	NA	NA	NA	NA
WP_011375095.1\|527668_529048_+	DnaD domain protein	NA	NA	NA	NA
WP_011375094.1\|529047_529974_+	primosomal protein DnaI	S5MU12	Brevibacillus_phage	3.8e-28	38.7
WP_011375093.1\|530285_532256_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	3.8e-102	34.0
532362:532385	attR	NA	NA	NA	NA

DBSCAN-SWA_2

634854 : 642919

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011374977.1\|634854_635181_-	heavy metal-binding domain-containing protein	M4STD1	Rhodobacter_phage	5.4e-06	34.6
WP_011374976.1\|635197_635563_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_096584663.1\|635648_636641_-	UDP-glucose 4-epimerase GalE	A0A1V0SG19	Hokovirus	7.9e-48	36.7
WP_096584666.1\|636785_639098_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.8e-77	31.1
WP_096584669.1\|639121_639640_+	adenine phosphoribosyltransferase	A0A2K9L2N8	Tupanvirus	5.6e-13	32.2
WP_011374972.1\|639732_640347_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	1.1e-15	58.2
WP_016265356.1\|640481_640724_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_011374970.1\|640804_641035_+	YneF family protein	NA	NA	NA	NA
WP_096584672.1\|641176_642919_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	9.9e-46	27.7

DBSCAN-SWA_3

721755 : 760147

Enterococcus_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011373852.1\|721755_722676_-\|transposase	IS30-like element ISLsa1 family transposase	Q9MBM9	Staphylococcus_prophage	9.2e-51	38.2
WP_056948747.1\|722773_724252_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_096584763.1\|724265_725915_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_025016360.1\|725931_726420_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_096584766.1\|726428_727229_+	ChbG/HpnK family deacetylase	NA	NA	NA	NA
WP_011374894.1\|727225_727834_+	SGNH/GDSL hydrolase family protein	A0A0S2SXG8	Bacillus_phage	1.0e-13	30.6
WP_011374893.1\|727889_728597_-	VIT family protein	NA	NA	NA	NA
WP_011374892.1\|728656_729337_-	VIT family protein	NA	NA	NA	NA
WP_011374891.1\|729511_730150_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_011374890.1\|730165_730585_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_096584769.1\|730603_731017_+	cupin domain-containing protein	NA	NA	NA	NA
WP_011374888.1\|731032_731353_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_016265300.1\|731656_732415_+	nicotinamide mononucleotide transporter	C1KFI0	Lactobacillus_virus	2.4e-81	61.4
WP_096584772.1\|732468_734304_-	pyruvate oxidase	G9E525	Ostreococcus_lucimarinus_virus	8.9e-13	24.8
WP_025016364.1\|734507_735266_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.0e-11	30.0
WP_011374884.1\|735262_736126_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_011374883.1\|736122_737124_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_056948736.1\|737670_738930_+	cytochrome P450	NA	NA	NA	NA
WP_082267781.1\|739527_739764_-\|transposase	transposase	NA	NA	NA	NA
WP_011374879.1\|739767_740550_-\|transposase	transposase	NA	NA	NA	NA
WP_011374878.1\|740492_740741_-\|transposase	transposase	NA	NA	NA	NA
WP_011374877.1\|740842_742189_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_011374876.1\|742304_742616_-	hypothetical protein	NA	NA	NA	NA
WP_056948729.1\|742637_743366_-	hypothetical protein	NA	NA	NA	NA
WP_011374874.1\|743387_743975_-	C39 family peptidase	NA	NA	NA	NA
WP_011374872.1\|744385_744529_-	hypothetical protein	NA	NA	NA	NA
WP_011374871.1\|744786_745221_-	universal stress protein	NA	NA	NA	NA
WP_096584775.1\|745447_746140_-	hypothetical protein	NA	NA	NA	NA
WP_076639187.1\|746261_746936_-	hypothetical protein	NA	NA	NA	NA
WP_016265287.1\|747152_747872_+	aquaporin family protein	M1HCP3	Acanthocystis_turfacea_Chlorella_virus	2.9e-28	34.1
WP_011374867.1\|748222_749596_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	5.1e-45	30.4
WP_011374866.1\|749647_750127_-	nucleoside 2-deoxyribosyltransferase	A0A1D3SPR3	Enterococcus_phage	3.8e-16	37.2
WP_011374865.1\|750259_750433_-	hypothetical protein	NA	NA	NA	NA
WP_096584778.1\|750590_752633_+	KUP/HAK/KT family potassium transporter	M1IAJ4	Acanthocystis_turfacea_Chlorella_virus	8.9e-70	34.9
WP_096584781.1\|752874_753570_+	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	5.6e-16	44.8
WP_096584784.1\|753596_753971_+	hypothetical protein	NA	NA	NA	NA
WP_011374861.1\|753990_754236_+	hypothetical protein	NA	NA	NA	NA
WP_096584787.1\|754235_755540_+	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.6e-85	39.9
WP_148664864.1\|755532_755778_+	hypothetical protein	E3W8I0	Leuconostoc_phage	2.6e-05	40.7
WP_099769415.1\|755767_756836_+\|transposase	IS3-like element IS1520 family transposase	Q6J1X2	Lactobacillus_phage	6.3e-27	34.9
WP_065825252.1\|756900_757830_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW47	unidentified_phage	1.8e-25	33.3
WP_011374858.1\|758485_758737_+	hypothetical protein	NA	NA	NA	NA
WP_056948015.1\|759451_760147_+	LysM peptidoglycan-binding domain-containing protein	A0A096XT26	Enterococcus_phage	5.0e-17	40.3

DBSCAN-SWA_4

906498 : 914065

Staphylococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096584934.1\|906498_907371_-	YitT family protein	M1Q1P6	Streptococcus_phage	8.2e-57	41.5
WP_056947591.1\|907518_908712_+\|tRNA	CCA tRNA nucleotidyltransferase	A0A249XS88	Mycobacterium_phage	3.9e-33	33.0
WP_011374705.1\|908780_909242_+	hypothetical protein	NA	NA	NA	NA
WP_096584937.1\|909354_911244_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.0e-48	29.3
WP_076647572.1\|911561_912512_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	2.7e-122	64.0
WP_025015767.1\|912522_913023_+	dihydrofolate reductase	G3MBI7	Bacillus_virus	3.5e-28	38.7
WP_025015768.1\|913219_914065_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	7.7e-20	44.2

DBSCAN-SWA_5

1277533 : 1327026

Anomala_cuprea_entomopoxvirus(12.5%)

holin,transposase,bacteriocin,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096585258.1\|1277533_1278163_-\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_011374343.1\|1278181_1278502_-	thioredoxin family protein	NA	NA	NA	NA
WP_011374342.1\|1278623_1278950_+	hypothetical protein	NA	NA	NA	NA
WP_011374341.1\|1279021_1279663_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_096585261.1\|1279830_1280661_-	phosphotransferase family protein	NA	NA	NA	NA
WP_041820776.1\|1280793_1281993_-	ABC transporter permease	NA	NA	NA	NA
WP_011374338.1\|1281995_1282724_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.5e-19	30.0
WP_011374337.1\|1282944_1283373_+	HIT family protein	D7NW73	Streptomyces_phage	3.8e-07	30.4
WP_011374336.1\|1283375_1283702_+	YtxH domain-containing protein	NA	NA	NA	NA
WP_049762126.1\|1283867_1284776_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_011374334.1\|1284836_1285805_-	HD domain-containing protein	NA	NA	NA	NA
WP_056948285.1\|1285794_1288506_-	AAA family ATPase	NA	NA	NA	NA
WP_076632396.1\|1288508_1289702_-	DNA repair exonuclease	NA	NA	NA	NA
WP_056948281.1\|1289836_1290181_-	YlbF family regulator	NA	NA	NA	NA
WP_056948279.1\|1290204_1292286_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_096585807.1\|1292488_1293331_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	5.4e-05	27.2
WP_096585264.1\|1293446_1294106_-	ABC transporter permease	NA	NA	NA	NA
WP_172425607.1\|1294102_1295035_-	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011374326.1\|1295049_1295676_-	ABC transporter permease	NA	NA	NA	NA
WP_035146539.1\|1295690_1296842_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.1e-22	32.7
WP_056948275.1\|1297113_1297581_-	arginine repressor	NA	NA	NA	NA
WP_142501179.1\|1297767_1300611_+	hypothetical protein	NA	NA	NA	NA
WP_011374321.1\|1300632_1300989_+	hypothetical protein	NA	NA	NA	NA
WP_011374320.1\|1300969_1301671_+	WxL domain-containing protein	NA	NA	NA	NA
WP_096585273.1\|1301688_1302744_+	DUF3324 domain-containing protein	NA	NA	NA	NA
WP_011374316.1\|1303419_1304715_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	2.2e-167	69.7
WP_011374315.1\|1304832_1305588_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_096585276.1\|1305613_1306828_-	phosphoglycerate kinase	NA	NA	NA	NA
WP_056948271.1\|1306928_1307942_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_011374312.1\|1307980_1309018_-	sugar-binding domain-containing protein	NA	NA	NA	NA
WP_096585279.1\|1309445_1310120_-	hypothetical protein	NA	NA	NA	NA
WP_056947469.1\|1310288_1311695_+	C69 family dipeptidase	NA	NA	NA	NA
WP_011373852.1\|1311982_1312903_+\|transposase	IS30-like element ISLsa1 family transposase	Q9MBM9	Staphylococcus_prophage	9.2e-51	38.2
WP_011374291.1\|1314637_1315063_-	hypothetical protein	NA	NA	NA	NA
WP_016264798.1\|1315040_1315631_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_096585281.1\|1315652_1317128_-	UbiD family decarboxylase	NA	NA	NA	NA
WP_011374288.1\|1317235_1318108_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011374287.1\|1318232_1318958_+	DUF554 domain-containing protein	NA	NA	NA	NA
WP_011374286.1\|1318997_1319237_-	hypothetical protein	NA	NA	NA	NA
WP_011374285.1\|1319245_1319488_-	hypothetical protein	NA	NA	NA	NA
WP_011374284.1\|1319646_1320999_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_096585284.1\|1321155_1321593_+	hypothetical protein	NA	NA	NA	NA
WP_096585288.1\|1321579_1322212_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_011374281.1\|1322356_1323397_-	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	A0A1W6JHY1	Lactococcus_phage	5.1e-13	33.8
WP_076645002.1\|1323566_1323851_-	hypothetical protein	NA	NA	NA	NA
WP_035146515.1\|1323934_1324258_+	hypothetical protein	NA	NA	NA	NA
WP_056947916.1\|1324330_1324567_-	hypothetical protein	NA	NA	NA	NA
WP_056947920.1\|1324799_1325087_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_011374275.1\|1325105_1325438_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_011374274.1\|1325578_1325761_-	hypothetical protein	NA	NA	NA	NA
WP_099769415.1\|1325956_1327026_-\|transposase	IS3-like element IS1520 family transposase	Q6J1X2	Lactobacillus_phage	6.3e-27	34.9

DBSCAN-SWA_6

1355769 : 1365388

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_056948808.1\|1355769_1356213_+	glucosaminidase domain-containing protein	A0A249Y0X5	Enterococcus_phage	3.5e-16	45.9
WP_025016311.1\|1356894_1357479_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.5e-51	53.4
WP_016264751.1\|1357703_1358228_+	DsbA family protein	NA	NA	NA	NA
WP_035146456.1\|1358342_1358798_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011374236.1\|1358889_1359834_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.3e-52	39.0
WP_016264749.1\|1359836_1360871_-	YvcK family protein	A1IMD5	Streptococcus_phage	9.0e-95	54.8
WP_011374234.1\|1360867_1361752_-	RNase adapter RapZ	A0A1P8D5W0	Corynebacterium_phage	8.4e-09	31.0
WP_016264747.1\|1361877_1362414_-	DUF308 domain-containing protein	NA	NA	NA	NA
WP_096585341.1\|1362535_1365388_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.3e-305	54.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP017932

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_AP017931

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection