CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP023658	Acetobacter pomorum strain BDGP5 plasmid pApBDGP5A, complete sequence	0 crisprs	csa3	0	0	2
NZ_CP023659	Acetobacter pomorum strain BDGP5 plasmid pApBDGP5B, complete sequence	0 crisprs	NA	0	0	0
NZ_CP023660	Acetobacter pomorum strain BDGP5 plasmid pApBDGP5C, complete sequence	0 crisprs	NA	0	0	1
NZ_CP023657	Acetobacter pomorum strain BDGP5 chromosome, complete genome	1 crisprs	cas3,cas2,cas1,cas4,cas7,cas8c,cas5,RT,csa3,PD-DExK,DinG,cas3HD	1	4	7

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2113 : 81974

Burkholderia_virus(28.57%)

transposase,integrase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010511145.1\|2113_3145_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_006115743.1\|4597_9724_-	DEAD/DEAH box helicase family protein	I6WLR1	Burkholderia_virus	0.0e+00	39.8
WP_081461418.1\|10178_10814_+	ParA family protein	W0LIU2	Mycobacterium_phage	2.7e-09	30.9
WP_019088965.1\|10810_11509_+	hypothetical protein	NA	NA	NA	NA
WP_006115744.1\|12239_13163_-	Plasmid Encoded RepA protein	NA	NA	NA	NA
WP_006115745.1\|13654_15145_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_006115870.1\|15985_17371_-\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	2.5e-31	29.4
WP_006117547.1\|17967_19170_-	porin	NA	NA	NA	NA
WP_019088957.1\|19156_19456_-	hypothetical protein	NA	NA	NA	NA
WP_006117546.1\|20222_22445_-	TonB-dependent receptor	NA	NA	NA	NA
WP_006117545.1\|22521_23052_-	hypothetical protein	NA	NA	NA	NA
WP_006117544.1\|23103_23283_+	hypothetical protein	NA	NA	NA	NA
WP_039892090.1\|23380_24373_+	TonB family protein	NA	NA	NA	NA
WP_088364821.1\|25312_26523_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	5.0e-97	64.0
WP_006117538.1\|26890_27358_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_006117537.1\|27431_28748_+	hypothetical protein	NA	NA	NA	NA
WP_100070304.1\|29703_31164_+	nitric oxide reductase large subunit	NA	NA	NA	NA
WP_010512344.1\|31170_31536_+	DUF488 family protein	NA	NA	NA	NA
WP_006115869.1\|31597_31987_+	PAS domain S-box protein	NA	NA	NA	NA
WP_006115868.1\|31983_32256_+	DUF1971 domain-containing protein	NA	NA	NA	NA
WP_010512346.1\|32269_32485_-	DUF2945 domain-containing protein	NA	NA	NA	NA
WP_006115867.1\|32520_33099_+	DUF488 domain-containing protein	A0A2K9L455	Tupanvirus	5.1e-23	40.0
WP_082823248.1\|33297_33783_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_006115450.1\|33907_35518_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.7e-111	42.3
WP_012812355.1\|35581_35929_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	5.6e-25	51.4
WP_012812356.1\|35925_36285_-\|transposase	transposase	A0A1B0YZU7	Pseudomonas_phage	1.3e-05	44.1
WP_006115449.1\|36802_38065_-	sodium:proton antiporter	A0A2H4J428	uncultured_Caudovirales_phage	3.3e-14	31.0
WP_003618711.1\|38196_38490_-	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	A0A2H4JBF4	uncultured_Caudovirales_phage	2.1e-17	48.9
WP_003618686.1\|38486_38747_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_006115447.1\|39339_40413_-	alkene reductase	NA	NA	NA	NA
WP_050793094.1\|40612_41080_-	hypothetical protein	NA	NA	NA	NA
WP_039891505.1\|42067_42802_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_039891503.1\|42869_43310_-	hypothetical protein	NA	NA	NA	NA
WP_096884314.1\|44354_46010_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_100070297.1\|46048_46936_+	AAA family ATPase	NA	NA	NA	NA
WP_006117296.1\|46928_47930_+	TniQ family protein	NA	NA	NA	NA
WP_039891983.1\|48534_48924_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_006117298.1\|48965_49697_-	hypothetical protein	NA	NA	NA	NA
WP_096884248.1\|49894_51105_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.6e-97	64.0
WP_006115451.1\|52768_53239_+	hypothetical protein	NA	NA	NA	NA
WP_006115452.1\|53257_54493_+	TolC family protein	NA	NA	NA	NA
WP_039891523.1\|54489_55644_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_006115454.1\|55643_58718_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_006115455.1\|58717_59389_+	response regulator transcription factor	NA	NA	NA	NA
WP_006115456.1\|59385_60738_+	HAMP domain-containing histidine kinase	A0A1B0VMK3	Pseudomonas_phage	8.9e-10	27.1
WP_006115457.1\|60794_61499_+	VIT family protein	NA	NA	NA	NA
WP_039891527.1\|61982_63203_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_039891524.1\|64923_67821_+	nitrite reductase small subunit NirD	NA	NA	NA	NA
WP_039891529.1\|69469_70147_+	DUF1028 domain-containing protein	NA	NA	NA	NA
WP_012813251.1\|70206_71466_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_006115465.1\|71465_72947_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_003630593.1\|73084_73492_+	enamine deaminase RidA	NA	NA	NA	NA
WP_003630594.1\|73614_75009_+	allantoin permease	NA	NA	NA	NA
WP_006117385.1\|75008_76625_+	alcohol dehydrogenase	A0A1V0S9M4	Catovirus	1.3e-47	29.0
WP_006117386.1\|76621_77776_+	acetylornithine deacetylase	NA	NA	NA	NA
WP_039892039.1\|77876_78797_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_006117388.1\|79121_80618_+	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_096884248.1\|80764_81974_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.6e-97	64.0

DBSCAN-SWA_2

123616 : 131395

uncultured_Caudovirales_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006115727.1\|123616_125230_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.5e-43	28.8
WP_006115729.1\|125672_126026_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006115730.1\|126022_126445_+	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	1.2e-48	67.9
WP_006115732.1\|126444_127740_+	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	3.6e-133	59.5
WP_012813274.1\|127763_128462_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	4.1e-83	69.7
WP_012813273.1\|128470_129550_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4J2Q2	uncultured_Caudovirales_phage	5.3e-82	56.2
WP_012813272.1\|129863_130205_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_006115735.1\|130201_130498_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_087651418.1\|130640_131395_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	5.5e-25	47.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP023657

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP023657_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023657_1

694941-697022

TypeI

I-C

Consensus_repeat	Method
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CRISPRCasFinder
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CRT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	PILER-CR

31 spacers

cas3,cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of NZ_CP023657_1

>merge|NZ_CP023657|1|694941-697022|CRISPRCasFinder,CRT,PILER-CR
TCGGCTATCCACGCTCCCGCACGGGGAGCGACTCTCGGATGGGCCTGCCGCCATCACTGCACTGTATGTTTCTATCCACGCTCCCGCACGGGGAGCGACAAATAGCACCCAACGATCTTTGTAGTAGAGCGGGTTTCTATCCACGCTCCCGCACGGGGAGCGACGCGATCTCTATATCGTATCCGTTGCGGGCACCACGTTTCTATCCACGCTCCCGCACGGGGAGCGACATGCTAAAGATTTGCTCCGGCAGGGGATAGACCCGTTTCTATCCACGCTCCCGCACGGGGAGCGACCCACGGGCATCGCGGCCTTGATCTACTGGCCTGAGTTTCTATCCACGCTCCCGCACGGGGAGCGACCAACGCCCAGACAGTAGCTGCACCCAGCGTGTTGTTTCTATCCACGCTCCCGCACGGGGAGCGACGCCATCATGGTTGCTGGAAATTACAAGCGCTCCAGTTTCTATCCACGCTCCCGCACGAGGAGCGACCCGATCTAACGAGTACCCAAGGATGTTCACATTGGTTTCTATCCACGCTCCCGCACGGGGAGCGACGCCACGGCGTAGCCTGTACCGCCACTCGATACGGTGTTTCTATCCACGCTCCCGCACGGGGAGCGACGGTCATGATGCAGCCCCTTAACATCCAGCACGAGGTTTCTATCCACGCTCCCGCACGGGGAGCGACATGCCTTTCACGAAGTTGTCCCGGTCTTCGGTGGTTTCTATCCACGCTCCCGCACGGGGAGCGACTTCTGATTTCAGGTTGGGATCTCGCCCAGCCCCCTGTTTCTATCCACGCTCCCGCACGGGGAGCGACTTCTGCCCCCATGCTGGCTGATCTGGGCGTGTCCGTTTCTATCCACGCTCCCGCACGGGGAGCGACCATAGCTTTGGCTGAAAAGCTATTGGCGGAATATGTTTCTATCCACGCTCCCGCACGGGGAGCGACGTTAAATTCCACTGCATAGCACCGGGCAATCTCTGGTTTCTATCCACGCTCCCGCACGGGGAGCGACGTTAAATTCCACTGCATAGCACCGGGCAATCTCTGGTTTCTATCCACGCTCCCGCACGGGGAGCGACGCGAGACAATGCGCGATTATCGCCGCCGTATTGAGTTTCTATCCACGCTCCCGCACGGGGAGCGACGCGAAAACAGATAAAAAATTCCCGCGCATGCGGGTTTCTATCCACGCTCCCGCACGGGGAGCGACACTAACAAAACCACAATGCCGCGCCGTTCCGCGTAGTTTCTATCCACGCTCCCGCACGGGGAGCGACCCATACTGCCCGTAGGTGTTTATCATTGCGTAGGGTTTCTATCCACGCTCCCGCACGGGGAGCGACGAAAAACTGCAACGTTTTACGGTCGAAAAAATGGGTTTCTATCCACGCTCCCGCACGGGGAGCGACGGTCATGCCGCAACTCCAGCGTTTTCAGGTTTTAGTTTCTATCCACGCTCCCGCACGGGGAGCGACCAACGCGATGGAGGAATGAATGACACTTATTGCGGTTTCTATCCACGCTCCCGCACGGGGAGCGACAACATAGCTACCTGCATGCGCGAACAGGCCAACGTTTCTATCCACGCTCCCGCACGGGGAGCGACTTTTCTCATCCGGTTTCCTGAATGCGAGCAGGACGTTTCTATCCACGCTCCCGCACGGGGAGCGACAGCCAGATGCAGGCCCTTTATTTGGAGTTCATAAACGTTTCTATCCACGCTCCCGCACGGGGAGCGACCTGGCGTTATGTTGCCGGTCAGTATTATTGCACGGTTTCTATCCACGCTCCCGCACGGGGAGCGACTCCAGTTCCCTGTCCACATCAGGCAGGCTTGCCAGTTTCTATCCACGCTCCCGCACGGGGAGCGACGAAAGCGCCTTGGCCATATCTCCCGTATAGCCGGTGTTTCTATCCACGCTCCCGCACGGGGAGCGACCGTGTTTCTTGCAGCTGTGCCACAGACGTTTTGAGTTTCTATCCACGCTCCCGCACGGGGAGCGACAAAGCGCCTTGGCCATATCTCCCGTATAGCCGGTGTTTCTATCCACGCTCCCGCACGGGGAGCGAC

>NZ_CP023657|1|1|694941-697022|CRISPRCasFinder
TCGGCTATCCACGCTCCCGCACGGGGAGCGAC	TCTCGGATGGGCCTGCCGCCATCACTGCACTGTAT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AAATAGCACCCAACGATCTTTGTAGTAGAGCGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGATCTCTATATCGTATCCGTTGCGGGCACCAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ATGCTAAAGATTTGCTCCGGCAGGGGATAGACCC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CCACGGGCATCGCGGCCTTGATCTACTGGCCTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CAACGCCCAGACAGTAGCTGCACCCAGCGTGTT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCCATCATGGTTGCTGGAAATTACAAGCGCTCCA
GTTTCTATCCACGCTCCCGCACGAGGAGCGAC	CCGATCTAACGAGTACCCAAGGATGTTCACATTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCCACGGCGTAGCCTGTACCGCCACTCGATACGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GGTCATGATGCAGCCCCTTAACATCCAGCACGAG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ATGCCTTTCACGAAGTTGTCCCGGTCTTCGGTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTCTGATTTCAGGTTGGGATCTCGCCCAGCCCCCT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTCTGCCCCCATGCTGGCTGATCTGGGCGTGTCC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CATAGCTTTGGCTGAAAAGCTATTGGCGGAATAT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GTTAAATTCCACTGCATAGCACCGGGCAATCTCTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GTTAAATTCCACTGCATAGCACCGGGCAATCTCTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGAGACAATGCGCGATTATCGCCGCCGTATTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGAAAACAGATAAAAAATTCCCGCGCATGCGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ACTAACAAAACCACAATGCCGCGCCGTTCCGCGTA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CCATACTGCCCGTAGGTGTTTATCATTGCGTAGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GAAAAACTGCAACGTTTTACGGTCGAAAAAATGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GGTCATGCCGCAACTCCAGCGTTTTCAGGTTTTA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CAACGCGATGGAGGAATGAATGACACTTATTGCG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AACATAGCTACCTGCATGCGCGAACAGGCCAAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTTTCTCATCCGGTTTCCTGAATGCGAGCAGGAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AGCCAGATGCAGGCCCTTTATTTGGAGTTCATAAAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CTGGCGTTATGTTGCCGGTCAGTATTATTGCACG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TCCAGTTCCCTGTCCACATCAGGCAGGCTTGCCA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GAAAGCGCCTTGGCCATATCTCCCGTATAGCCGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CGTGTTTCTTGCAGCTGTGCCACAGACGTTTTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AAAGCGCCTTGGCCATATCTCCCGTATAGCCGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC

>NZ_CP023657|1|1|694941-697022|CRT
TCGGCTATCCACGCTCCCGCACGGGGAGCGAC	TCTCGGATGGGCCTGCCGCCATCACTGCACTGTAT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AAATAGCACCCAACGATCTTTGTAGTAGAGCGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGATCTCTATATCGTATCCGTTGCGGGCACCAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ATGCTAAAGATTTGCTCCGGCAGGGGATAGACCC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CCACGGGCATCGCGGCCTTGATCTACTGGCCTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CAACGCCCAGACAGTAGCTGCACCCAGCGTGTT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCCATCATGGTTGCTGGAAATTACAAGCGCTCCA
GTTTCTATCCACGCTCCCGCACGAGGAGCGAC	CCGATCTAACGAGTACCCAAGGATGTTCACATTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCCACGGCGTAGCCTGTACCGCCACTCGATACGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GGTCATGATGCAGCCCCTTAACATCCAGCACGAG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ATGCCTTTCACGAAGTTGTCCCGGTCTTCGGTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTCTGATTTCAGGTTGGGATCTCGCCCAGCCCCCT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTCTGCCCCCATGCTGGCTGATCTGGGCGTGTCC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CATAGCTTTGGCTGAAAAGCTATTGGCGGAATAT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GTTAAATTCCACTGCATAGCACCGGGCAATCTCTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GTTAAATTCCACTGCATAGCACCGGGCAATCTCTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGAGACAATGCGCGATTATCGCCGCCGTATTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGAAAACAGATAAAAAATTCCCGCGCATGCGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ACTAACAAAACCACAATGCCGCGCCGTTCCGCGTA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CCATACTGCCCGTAGGTGTTTATCATTGCGTAGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GAAAAACTGCAACGTTTTACGGTCGAAAAAATGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GGTCATGCCGCAACTCCAGCGTTTTCAGGTTTTA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CAACGCGATGGAGGAATGAATGACACTTATTGCG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AACATAGCTACCTGCATGCGCGAACAGGCCAAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTTTCTCATCCGGTTTCCTGAATGCGAGCAGGAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AGCCAGATGCAGGCCCTTTATTTGGAGTTCATAAAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CTGGCGTTATGTTGCCGGTCAGTATTATTGCACG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TCCAGTTCCCTGTCCACATCAGGCAGGCTTGCCA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GAAAGCGCCTTGGCCATATCTCCCGTATAGCCGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CGTGTTTCTTGCAGCTGTGCCACAGACGTTTTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AAAGCGCCTTGGCCATATCTCCCGTATAGCCGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC

>NZ_CP023657|1|1|695008-697022|PILER-CR
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AAATAGCACCCAACGATCTTTGTAGTAGAGCGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGATCTCTATATCGTATCCGTTGCGGGCACCAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ATGCTAAAGATTTGCTCCGGCAGGGGATAGACCC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CCACGGGCATCGCGGCCTTGATCTACTGGCCTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CAACGCCCAGACAGTAGCTGCACCCAGCGTGTT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCCATCATGGTTGCTGGAAATTACAAGCGCTCCA
GTTTCTATCCACGCTCCCGCACGAGGAGCGAC	CCGATCTAACGAGTACCCAAGGATGTTCACATTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCCACGGCGTAGCCTGTACCGCCACTCGATACGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GGTCATGATGCAGCCCCTTAACATCCAGCACGAG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ATGCCTTTCACGAAGTTGTCCCGGTCTTCGGTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTCTGATTTCAGGTTGGGATCTCGCCCAGCCCCCT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTCTGCCCCCATGCTGGCTGATCTGGGCGTGTCC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CATAGCTTTGGCTGAAAAGCTATTGGCGGAATAT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GTTAAATTCCACTGCATAGCACCGGGCAATCTCTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GTTAAATTCCACTGCATAGCACCGGGCAATCTCTG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGAGACAATGCGCGATTATCGCCGCCGTATTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GCGAAAACAGATAAAAAATTCCCGCGCATGCGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	ACTAACAAAACCACAATGCCGCGCCGTTCCGCGTA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CCATACTGCCCGTAGGTGTTTATCATTGCGTAGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GAAAAACTGCAACGTTTTACGGTCGAAAAAATGG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GGTCATGCCGCAACTCCAGCGTTTTCAGGTTTTA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CAACGCGATGGAGGAATGAATGACACTTATTGCG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AACATAGCTACCTGCATGCGCGAACAGGCCAAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TTTTCTCATCCGGTTTCCTGAATGCGAGCAGGAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AGCCAGATGCAGGCCCTTTATTTGGAGTTCATAAAC
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CTGGCGTTATGTTGCCGGTCAGTATTATTGCACG
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	TCCAGTTCCCTGTCCACATCAGGCAGGCTTGCCA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	GAAAGCGCCTTGGCCATATCTCCCGTATAGCCGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	CGTGTTTCTTGCAGCTGTGCCACAGACGTTTTGA
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC	AAAGCGCCTTGGCCATATCTCCCGTATAGCCGGT
GTTTCTATCCACGCTCCCGCACGGGGAGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023657.1\|WP_006116166.1\|702048_702729_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NZ_CP023657.1\|WP_006116170.1\|706877_707708_-\|sulfotransferase	unknown	unknown	gnl\|CDD\|379204
NZ_CP023657.1\|WP_157772570.1\|691321_691489_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023657.1\|WP_006116162.1\|698633_699281_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NZ_CP023657.1\|WP_006116150.1\|679129_681412_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379075
NZ_CP023657.1\|WP_035353185.1\|685268_685532_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023657.1\|WP_035353187.1\|681408_682809_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|378508
NZ_CP023657.1\|WP_006116159.1\|697294_697585_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP023657.1\|WP_035351827.1\|703936_704278_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023657.1\|WP_035353176.1\|692404_694798_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NZ_CP023657.1\|WP_155006632.1\|691954_692137_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023657.1\|WP_081461434.1\|687667_687982_+\|terminase-small-subunit	unknown	unknown	gnl\|CDD\|377071
NZ_CP023657.1\|WP_006116153.1\|688289_688622_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|226679
NZ_CP023657.1\|WP_006116164.1\|699287_700235_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NZ_CP023657.1\|WP_035351829.1\|704676_705018_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP023657.1\|WP_035353173.1\|697587_698628_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP023657.1\|WP_006116155.1\|688618_688873_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP023657.1\|WP_006116165.1\|700231_702052_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_CP023657.1\|WP_157772569.1\|685531_687640_-\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381594
NZ_CP023657.1\|WP_006116169.1\|705925_706888_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117

Protein	Function_ID	Function_description	E-value
NZ_CP023657.1\|WP_006116166.1\|702048_702729_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.49294e-109
NZ_CP023657.1\|WP_006116170.1\|706877_707708_-\|sulfotransferase	gnl\|CDD\|379204	pfam13469, Sulfotransfer_3, Sulfotransferase family.	1.08537e-09
NZ_CP023657.1\|WP_006116162.1\|698633_699281_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.93147e-45
NZ_CP023657.1\|WP_035353187.1\|681408_682809_+\|ATP-binding-protein	gnl\|CDD\|378508	pfam10923, DUF2791, P-loop Domain of unknown function (DUF2791). This is a family of proteins found in archaea and bacteria. This domain contains a P-loop motif suggesting it binds to a nucleotide such as ATP.	0
NZ_CP023657.1\|WP_006116159.1\|697294_697585_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.01134e-32
NZ_CP023657.1\|WP_035353176.1\|692404_694798_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.95425e-56
NZ_CP023657.1\|WP_006116150.1\|679129_681412_+\|hypothetical-protein	gnl\|CDD\|379075	pfam13208, TerB_N, TerB N-terminal domain. The TerB_N domain is found N-terminal to TerB, and TerB_C containing proteins. It has a predominantly alpha-helical structure and contains an absolutely conserved glutamate. The presence of a conserved acidic residue suggests that it might chelate metal like TerB. These proteins occur in a two-gene operon containing an AAA+ ATPase and SF-II DNA helicase suggesting a role in stress-response or phage defense.	3.4159e-40
NZ_CP023657.1\|WP_081461434.1\|687667_687982_+\|terminase-small-subunit	gnl\|CDD\|377071	pfam03592, Terminase_2, Terminase small subunit. Packaging of double-stranded viral DNA concatemers requires interaction of the prohead with virus DNA. This process is mediated by a phage-encoded DNA recognition and terminase protein. The terminase enzymes described so far, which are hetero-oligomers composed of a small and a large subunit, do not have a significant level of sequence homology. The small terminase subunit is thought to form a nucleoprotein structure that helps to position the terminase large subunit at the packaging initiation site.	3.8908e-23
NZ_CP023657.1\|WP_006116153.1\|688289_688622_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|226679	COG4226, HicB, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	3.62241e-47
NZ_CP023657.1\|WP_006116164.1\|699287_700235_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.17807e-141
NZ_CP023657.1\|WP_035353173.1\|697587_698628_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP023657.1\|WP_006116155.1\|688618_688873_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	8.32407e-06
NZ_CP023657.1\|WP_006116165.1\|700231_702052_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NZ_CP023657.1\|WP_157772569.1\|685531_687640_-\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381594	cd00254, LT-like, lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	3.35424e-09
NZ_CP023657.1\|WP_006116169.1\|705925_706888_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.74415e-28

>NZ_CP023657.1|WP_035353176.1|692404_694798_-|CRISPR-associated-helicase/endonuclease-Cas3
MLYAHSLPETPDKKGWEPLLEHLECVARCAARFASPFGCAVLAEAAGLLHDLGKASEEYQDYISKQAAKGPDHSTAGAREAVARYGKIWGRLIAFVVAGHHAGLTNAFQSERWSPTPLNERLDPTSRIIPDYSRWSSLGLKLPEQADLKPTRIFQPAPDYPGFREFFLTHMLFSALADADCLETERFYAEAAGLPLPARGGQITRKHLENLRAEMAARCNQATPLNRLRAEILEHAVGKASLAPGLFTLTVPTGGGKTLTSLSFALEHALKHGLRRVIYVIPYTSILEQTAEIFRDVLKSPDDILEHHSGFEWEKRAPDAERDSEHEGREGLDKLRRDAENWDAPIIVTTSVQFFESLFAAKKSRLRKLHNIAQSVVVLDEVQTLPVSLLRPCMAALDELARNYGTSLVLCTATQPALRKCDAALPALENGPAQGFDIDQQRELAPDPERLYATLKRVTVEWLDQPVTDEEIAARFSDCPQMLCIVNTRAHAQELFETINNLPGARHLTTLMCPMHRRQVLAEIRQDLQQKKPVRLVSTSLIEAGVDVDFPEVWRAAAGLSSVAQAAGRCNREGRLDGLGRTVVFESLDARKTVDQDEGNSSSQKKNLRILRSMLPFWQATRTIRRKGVDPLSLKGMHLYYQELYFNQGYEALDAATLPSGKSGKAGEKYPILPAVQRTASGMNLPFATIASAFRMIDTALAPVIIQWDEDAAQVVKQLQFMPYPTPRILRILQHYSVPVPPDVRMKLVMAGVCTLLHPEVFGDRFVVLEQNNDLYSAQTGLRLDDPTWRSEESNIF
>NZ_CP023657.1|WP_155006632.1|691954_692137_+|hypothetical-protein
MRKLSEILGTHNTTVQRWSKGKQLIPNNLAEWLEAQAKFRLEHPLPKGWEENRVPSQEEL
>NZ_CP023657.1|WP_157772570.1|691321_691489_+|hypothetical-protein
MRELAICTVSLCAIAFLLMAAIITLAPEPSGDGFEQLIKAASRFFSVADQLKLLD
>NZ_CP023657.1|WP_006116155.1|688618_688873_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MKAKHRRTLELIFKRPVSGNVPWADIEALFVSLGAEVSEREGSRIGVFLFDEVKVFHRPHPKPDTDKGAVASVRKWLEQNGVTP
>NZ_CP023657.1|WP_006116153.1|688289_688622_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MNNVMEIGGHRAVIQFDPEIGMFRGEFLGLNGGADFYADSVAGLQQEGETSLRVFMEMCAEKGIDPVKHYSGRFVVRLPEDVHARAAEIAAARGISLNRLVQDVLAQVEG
>NZ_CP023657.1|WP_081461434.1|687667_687982_+|terminase-small-subunit
MHDDDTLGTQQVQAAIRAGYSEKTSRSIAQRLLTNVDIQNAISEAQKARSKRTQITQDRVLQEFAKIGFSDIRKRSGFCNQSAREAATFVILHRPRKVSLRWSF
>NZ_CP023657.1|WP_157772569.1|685531_687640_-|transglycosylase-SLT-domain-containing-protein
MPDNDDSFIEAGIRFTFDPEGFLRGSAEAQDALESTLAEMINFRREAQKQEQQLKDAIPGIASALGASVDEVKDAIKDLKKSEQEAAKETARVQKEESRNALAEKRRAVREEEQLARQQQREEMARLRERQQAIREIRDTALAAVGATSLIGGTRNIVGMVGNVAANGANVLNMAGKTGFSAREILAVGEAGALTPGSSRQEALQSMNALAQARTEVHLNGQSQLTDLLANRYGVHISHIMNGSYETSMQHIIADLRRRGHSEQSLIAILEQSGLTSGGWSNEVLRGQDMHQRIQQGYSLTRHMADNLQQMEKVDEQMKHLGEMWVQFKKDIAIDMLPAMESVSGLLEKADKLAVEHPDAARHLTEIAAVITALSPILAGIGGVVGTTAILKLALSKGGCGCARNGKEETGTLEESSANISEDAAKKQALRKSEKEVERRASTGLLSRLLMGGNYAFDLYAFSEYFPHAASWLLGQGWDNEHPTTFHGNAKGLPQHLTPDMRNKQMHLSELEKKYGLPAGMLDGMWAKESSRGLHAGKSRAGALGDFQIMPDVAAASGIDPNNFYQSAEYAAKRMHGNMVQYGTIAAALAEYNWGGGNLKKDMSLHGGDWQRYAPNETQDYISSISRFVSASQQIHAMNKQVNASRAIRGGAVHTDNRQTTTMTMHVQNVNVRANDPQQMVQKVAQSNNHMLTAASVDTGVM
>NZ_CP023657.1|WP_035353185.1|685268_685532_-|hypothetical-protein
MAGVQLPNIISMARCLADKLYEDTKDLQNFQALEAGITGGEYAIWGFMKANGDSDEVARDCCLLFMKSVHERWRELLMKEAQPVGNA
>NZ_CP023657.1|WP_035353187.1|681408_682809_+|ATP-binding-protein
MTNLSIAASDGTRTAEKIKPKDRDGVIQALRAGVVPRSGIQLVQVGRAGEVNQVVQDVKRIADGGSAVRFIIGDYGAGKTFFLNLARSIAMQSKLVVAHADLSPDRRLQASGGQARSLYAELMRNMATRTKQGGGALASVVERFIMEAQASAKASGRKIGDIIQERLLPIQELVSGYDFATVIECYWRAFEDGSESGKAAALRWLRGEYALKTEAREALGVRSIIDDASVYDYLKVMSRFVTLAGYSGFLVMLDECVNLFKLVSAQSRNANYEQILRIVNDVLQGSAESLGVYFGGTPEFLMDSRRGLYSYEALRSRLAENSFARNGLVDLSGPVIRLQSLTPEDLYILLSKLRHVFAYGDQSRYLVPDEVFKAFMTHCNQKIGEAYFRTPRNTIKAFLDLLAIMEQNPQAQWQELVDQSEVAPDAPLAGGDIVDNDNKDTPSATGPSTTGSTQTSPDDDLADFRL
>NZ_CP023657.1|WP_006116150.1|679129_681412_+|hypothetical-protein
MFSWLKRIFSGSEIPDTTNKAARKETVASLPAHGHSSHAQRVFPNDEVKSAPYGQARSHKKDDAHWALPGEKVTVHGFEIADGMVYVGNFLTAAPDGGWNTDTPAPCLIRPSLKVASGAPQTNLDLGYWPSYTDITLNQRLTYLHWLASGKSDTSYPMGYPFLYFYGLERRLVADSPPIDEEALLIAEVERLRSLFRNNNSFVNYSTELLNFIEMKHAVTDIPRVEAWKPDLAALGDHMSPLLQVKLGLHVLRGMPLDVDLAIAGILSLPPHLTGLWPRIATTRARPEFIELMRHRFNQKFPKGFRLRDKKESRLNLSYRSASQYLHASIKFDGFDRLPDPAQLTWTKMIKLCEGVREDLTAFAKVVGKKRERADSMAAALMLPVELGERETVRSFRAWLGDLPQPLANVPLEELGLRCFGSGKTASGLRQACDMSAMLARVGYGMEPDPTYGGTRPGENIILFRIGDTQGQLTPVGADFCTATLIMTAIGPAAKTLTLRSKLVDDLTTRLRLTPHETKRLTARLQLLPERLPTLGRLKTIVESVEPEQRTAIASLAASVAVTIGETDQGMMVALERLYEAFGLGRQELYTVLHQSTAATASCAAEPIVVEDGKSRRRGHRIPAPPSKAKSQDGIVIDMSKVDVILQETKEVDAILAPIYEDEASEIPISVAVSPTLEQGTKFVGLGPEQARLLEALVNQPEWTRFGFEAKARELGLMPDGALEAINEWAYDTFDEELIVDGDPLIINMALLADAPGASS
>NZ_CP023657.1|WP_006116159.1|697294_697585_-|CRISPR-associated-endonuclease-Cas2
MLVLITYDVNTEDAAGRRRLRRVARACLDYGQRVQHSVFECEVDPAQWAELRARLLDEADSAKDSLRFYQLGAKGRQRVEHVGAKPVLDLDGTLVF
>NZ_CP023657.1|WP_035353173.1|697587_698628_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKHLNTIYVTTEDAWLRKDGANIVVEVEGKERGRAPLHLLEGIMCFGRIGASPALLAACAESGIAFSYLSPIGRFLARVEGPRSGNVLLRRAQYRVADDNTRSVLIARYIVAAKVANQRTVIRRVLRDYGASSPEASQKALQAAEAWLTDTTRRIVKVTDMDSLRGIEGEAARVYFSVFNLFIRSEDPAFQFGGRSRRPPLDRVNALLSFLYALLGHDCRSALESVGLDPQVGFLHADRPGRASLALDLMEEFRPVLADRLALNLINRAQVRAADFTCHEGGGITLHDDARKTVLTAWQERKKQEIRHPFLGETMTFGLVAHMQALLLSRYLRGELDAYPAFIWK
>NZ_CP023657.1|WP_006116162.1|698633_699281_-|CRISPR-associated-protein-Cas4
MMPKPDQRQDEENLVPVSALQHYLFCPRQCALIHIEQQWAENGATVEGRLLHERVDSGVPDRKRGVRTLRTLPIRSFALGIYGKADAVELHGTGSTLIPYPVEYKRGSPKPHHADEVQLCAQALCLEEMFGCAVSEGALFYDRPHRRTTVQFDQDLRDLTQKTAQKVQDMLAAGKTPQPVWNKGCKHCSLEAICQPRRLEKPLCVEKWFLENLED
>NZ_CP023657.1|WP_006116164.1|699287_700235_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MNKPVENRYEFVLYFDVTNGNPNGDPDAGNLPRLDPETNKGLVSDVALKRKVRNYISAVKEGDPGFEIYVSEGATLNVQNKKSWAAVMPDVTKDEEMKKLPKETEKALALTKWMCANFWDIRTFGAVMTTAVNAGQVRGPVQFAFARSVEPIVPLEISITRMAATTEADAEKKGGRTMGRKHIVPYGAYRVHGFVSAPLASHPVKGTGFSEEDLELLWSALLNMFELDHSAARGEMSARKLIVFKHASKLGNARAQDLFDRVKTFRTYQGSSYQVDHGSAQNPKMDNWPPARFWNDYAVVIDRENLPDGVEIIER
>NZ_CP023657.1|WP_006116165.1|700231_702052_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTEQIQQGILQALVRFYDRMQNAPALGWSQVKFGWAIVLNESGHPVDVMDLRDQSGKKPANRFFMVPAEVKRTAGISPNFLWDKSSYVLGKTAGAGKRTAQEHAAFVKKNLERIAGVEDAGLLALKAFLENWSPERFESEPFQTDMLDANIMFRLDGDARYIHERPAARKLIEARALEADGPEDRIFCLVTGENSKPARLHPAIKGVEGAQIAGASLVSFNCDAFTSYGKAQGENAPTSEGAAFRYGAALNSMLQRGSLNRVARPIGDTTVVFWAEASDRQAAEAADAFGAIALSSDNKDDAEVEKVSETLKRVSRGEALHTIRPDLGEGTRFYVLGLAPNAARLSVRFWLCDTLDAFARNLAMHYQDIAVEPAPWRNLPSPFLLAVKTTAMLEKADNIPKRLVADILNAILTGRAYPRTWLSSVIMRLRAGDDPTGWHAAAARAVLQRMKRKINPTISEKESVPVSLNRDYPNIGYQLGRLFAVYELAQRAALGGVNTSMRDKYFGAASATPASVFPVIIRNGQNHLGVVRKKLAGWSVIIEKELEEIFNKISPEEPSSFPRSLHLEQQGEFALGYYHQRSAKLAGQKSNQSLPEIENDQEDEDA
>NZ_CP023657.1|WP_006116166.1|702048_702729_-|type-I-C-CRISPR-associated-protein-Cas5
MGIRLHIWGERACFTRPELKAERVSYDVITPSAARGILEAIHWKPAIRWHIDRIHVLKPIQFGSFRRNEVSAKANARNAATAMKAGTTAGLGLVAEENRQQRAAMILLDVAYVVEAHFTMTDRAGPDDNPAKHISTFNRRAERGQCFHRPCLGTREFPAEFQLLPEEAALPHSDFLLQTQAAGDVDLGWMLHDIDFTNGKISKFFRARIHNGIIDVPPFDSPELAA
>NZ_CP023657.1|WP_035351827.1|703936_704278_+|hypothetical-protein
MFPRLTNLGASSFGEDPEFFGDTLFEVIEDAPQGHFLSFKQQAVNELRTLLAYSDVDLDRVSWAVLGMNPMADIEEPPNWGSFPSLRAFWSAVLHAFENDPEVRAGKEIDRNV
>NZ_CP023657.1|WP_035351829.1|704676_705018_-|hypothetical-protein
MFPRLTNLGASSFGEDPELFGDTLFEVIEDAPRGHFLPFKQQAVNELRTLLAYSDVDLDRVSWAVLSINPTADVEEPPNWGNFPSLRAFWSAVLHAFENDPEVRAGKEIDPDM
>NZ_CP023657.1|WP_006116169.1|705925_706888_+|helix-turn-helix-transcriptional-regulator
MTKKSIESTPPLDAPESSQTDITQSSMIRLNAYTRLIALQTGLQILYWDAQTKHDFSYSAYHDDDLIYFGAYTGGNSHMATRCWDGLTTYDTLSRPDDAYVAYRPGCRIDFTKTAGAGTGVTITLSPTTLASLSAEDATCLDQKLRSGHYFNQVRGGRQLLSFANALRSVGTSPKQPGSQLQMLGQSLSFMGSLIEQICHITPPNISLSEREIRRLNDTRDMLLADLASPPRVDQLARHAGMSVSRLQRHFRMLFGSTIYALFQKERMHEAYRQLVKDDESILTIATRLGYANPGHFSAAFRKQFGINPSELRRIPRLRR
>NZ_CP023657.1|WP_006116170.1|706877_707708_-|sulfotransferase
MSDSSSSVHVISGLPRSGSTLLAALLRQNPHIIAARHNTPVMPMLIRIMSLMSEGEYRTEFKNGQWQQLMRGIVRSYLNPGAQNHVMLDINREWCAHAGLLNSLYPQAKIICCVRDPVWILNSFEHLITRDPLLGSQLVPIAHRGNQHDRIDYLVSRDGAFGYAWRLLTEVFFGPFSDKVIFVDYDRFVREPGFVMERLTQLLGIRPFAYNFEHIETPDAAAFDAALGTPGLHCLHQSVVASRKRLILPPHIVERMAHQMFWRKPDLNSGGAVVIA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP023657_1	1.13\|695765\|34\|NZ_CP023657\|CRISPRCasFinder,CRT,PILER-CR	695765-695798	34	NZ_CP023657.1	275225-275258	1	0.971

1. spacer 1.13|695765|34|NZ_CP023657|CRISPRCasFinder,CRT,PILER-CR matches to position: 275225-275258, mismatch: 1, identity: 0.971

ttctgcccccatgctggctgatctgggcgtgtcc	CRISPR spacer
ttctgcctccatgctggctgatctgggcgtgtcc	Protospacer
*******.**************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP023657_1	1.11\|695633\|33\|NZ_CP023657\|CRISPRCasFinder,CRT,PILER-CR	695633-695665	33	MG251388	Pseudomonas phage Psp6, complete genome	29760-29792	6	0.818
NZ_CP023657_1	1.13\|695765\|34\|NZ_CP023657\|CRISPRCasFinder,CRT,PILER-CR	695765-695798	34	NZ_CP034818	Paracoccus sp. Arc7-R13 plasmid unnamed8, complete sequence	20876-20909	8	0.765
NZ_CP023657_1	1.17\|696031\|34\|NZ_CP023657\|CRISPRCasFinder,CRT,PILER-CR	696031-696064	34	NZ_CP032703	Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence	201551-201584	9	0.735
NZ_CP023657_1	1.1\|694973\|35\|NZ_CP023657\|CRISPRCasFinder,CRT	694973-695007	35	NZ_CP040764	Paracoccus sp. 2251 plasmid unnamed3, complete sequence	39545-39579	11	0.686

1. spacer 1.11|695633|33|NZ_CP023657|CRISPRCasFinder,CRT,PILER-CR matches to MG251388 (Pseudomonas phage Psp6, complete genome) position: , mismatch: 6, identity: 0.818

atgcctttcacgaagttgtcccggtcttcggtg	CRISPR spacer
atgttcttgacgaagttgtctcggtcttcggtc	Protospacer
***...** ***********.***********

2. spacer 1.13|695765|34|NZ_CP023657|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034818 (Paracoccus sp. Arc7-R13 plasmid unnamed8, complete sequence) position: , mismatch: 8, identity: 0.765

ttctgcccccatgctggctgatctgggcgtgtcc	CRISPR spacer
tttcgacgtgatgctggctgagctgggcctgtcc	Protospacer
**..* * . *********** ****** *****

3. spacer 1.17|696031|34|NZ_CP023657|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032703 (Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

gcgagacaatgcgcgattatcgccgccgtattga	CRISPR spacer
gctgcatgctgcgcgcttatcgccgccatattgt	Protospacer
** . *.. ****** ***********.*****

4. spacer 1.1|694973|35|NZ_CP023657|CRISPRCasFinder,CRT matches to NZ_CP040764 (Paracoccus sp. 2251 plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.686

tctcggatgggcctgccgccatcactgcactgtat	CRISPR spacer
cggcggatgggcctggcgccatcaccgcaaatggc	Protospacer
.  ************ *********.***    ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

56498 : 90308

Rhodobacter_phage(18.75%)

transposase,tail,integrase,head

attL 52790:52805|attR 83371:83386

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
52790:52805	attL	NA	NA	NA	NA
WP_035353466.1\|56498_57677_-\|integrase	tyrosine-type recombinase/integrase	A0A221SAN4	Ralstonia_phage	7.7e-50	34.6
WP_006115424.1\|58166_59537_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_096884248.1\|60319_61530_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.6e-97	64.0
WP_006115422.1\|61916_62375_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_050793091.1\|62361_62721_+	DMT family transporter	NA	NA	NA	NA
WP_006115420.1\|62960_64061_-	hypothetical protein	NA	NA	NA	NA
WP_050793090.1\|64057_64807_-	helix-turn-helix transcriptional regulator	H6WBQ3	Rhodobacter_phage	3.4e-11	30.8
WP_081461406.1\|65027_65312_+	hypothetical protein	NA	NA	NA	NA
WP_006115417.1\|65308_66127_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_006115416.1\|66123_66396_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_006115415.1\|66392_66845_+	hypothetical protein	NA	NA	NA	NA
WP_006115414.1\|66844_68830_+\|transposase	transposase	A0A1B1P6Z4	Rhodovulum_phage	7.2e-133	41.9
WP_035353473.1\|68873_69833_+	AAA family ATPase	A0A0C4UQR3	Shigella_phage	2.1e-45	38.9
WP_035353476.1\|69837_70119_+	hypothetical protein	NA	NA	NA	NA
WP_035353479.1\|70118_70361_+	hypothetical protein	NA	NA	NA	NA
WP_035353482.1\|70348_70681_+	hypothetical protein	NA	NA	NA	NA
WP_096884251.1\|70692_71316_+	DUF3164 family protein	A0A2P9JZH0	Alteromonadaceae_phage	2.9e-16	27.5
WP_035353552.1\|71366_71747_+	regulatory protein GemA	F8TVB3	EBPR_siphovirus	1.8e-13	40.2
WP_006115410.1\|71739_72438_+	DUF2786 domain-containing protein	A0A2P9JZH4	Alteromonadaceae_phage	7.8e-26	34.9
WP_035353485.1\|72434_72743_+	hypothetical protein	NA	NA	NA	NA
WP_050793088.1\|72919_73297_+	hypothetical protein	NA	NA	NA	NA
WP_035353488.1\|73357_74077_+	hypothetical protein	A0A223FUQ9	Acinetobacter_phage	8.6e-20	30.2
WP_035353490.1\|74149_74584_+	hypothetical protein	NA	NA	NA	NA
WP_035353493.1\|74586_74889_+	hypothetical protein	NA	NA	NA	NA
WP_139018854.1\|75034_75340_+	hypothetical protein	NA	NA	NA	NA
WP_006115547.1\|75342_75936_+	DUF3486 family protein	NA	NA	NA	NA
WP_035353497.1\|75919_77494_+	hypothetical protein	Q6QIC1	Burkholderia_phage	5.1e-126	51.3
WP_035353499.1\|77490_77733_+	hypothetical protein	NA	NA	NA	NA
WP_035353501.1\|77732_77978_+	hypothetical protein	NA	NA	NA	NA
WP_100070281.1\|77979_79695_+	DUF935 family protein	M4SPR8	Rhodobacter_phage	6.1e-88	33.8
WP_157772567.1\|79687_80893_+	hypothetical protein	J9STJ7	Pseudomonas_phage	3.7e-39	35.5
WP_006115541.1\|81022_81541_+	virion morphogenesis protein	A0A1B1P725	Rhodovulum_phage	1.8e-11	35.4
WP_006115540.1\|81760_82753_+	hypothetical protein	M4SNT6	Rhodobacter_phage	5.3e-36	48.3
WP_035353507.1\|82739_83186_+	hypothetical protein	NA	NA	NA	NA
WP_006115539.1\|83189_84140_+\|head	head protein	A0A1B0T6J4	Pelagibaca_phage	3.2e-54	42.4
83371:83386	attR	NA	NA	NA	NA
WP_006115538.1\|84142_84538_+	hypothetical protein	NA	NA	NA	NA
WP_006115537.1\|84537_84960_+	DUF1320 domain-containing protein	A0A2P9JZJ4	Alteromonadaceae_phage	9.2e-06	33.3
WP_035353510.1\|84953_85583_+	hypothetical protein	NA	NA	NA	NA
WP_035353513.1\|85579_85789_+	hypothetical protein	NA	NA	NA	NA
WP_006115536.1\|85785_87273_+\|tail	Mu-like prophage FluMu tail sheath protein	NA	NA	NA	NA
WP_006115535.1\|87275_87635_+	hypothetical protein	NA	NA	NA	NA
WP_035353516.1\|87631_87997_+	hypothetical protein	NA	NA	NA	NA
WP_006115534.1\|88115_90308_+\|tail	phage tail tape measure protein	NA	NA	NA	NA

DBSCAN-SWA_2

974247 : 994505

Aeromonas_phage(40.0%)

terminase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_035354190.1\|974247_975510_-	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.2e-29	38.7
WP_035354323.1\|975582_976029_-	hypothetical protein	NA	NA	NA	NA
WP_006117091.1\|976152_976722_-	hypothetical protein	NA	NA	NA	NA
WP_035354193.1\|976728_977826_-	hypothetical protein	A0A077KC23	Edwardsiella_phage	3.8e-11	33.8
WP_096884263.1\|977833_978412_-	DUF2612 domain-containing protein	H9C0Y0	Aeromonas_phage	6.2e-29	42.0
WP_006117088.1\|978411_979647_-	hypothetical protein	A0A2R3UAL9	Myoviridae_environmental_samples	1.6e-58	38.5
WP_006117087.1\|979633_979987_-	hypothetical protein	NA	NA	NA	NA
WP_035354196.1\|979998_980688_-\|plate	baseplate assembly protein	A0A2R3UAK1	Myoviridae_environmental_samples	2.2e-36	45.3
WP_035354199.1\|980684_981611_-	hypothetical protein	Q2NP99	Xanthomonas_phage	7.7e-13	29.6
WP_006117084.1\|981607_981928_-	hypothetical protein	A0A191ZDK0	Acinetobacter_phage	2.4e-06	35.1
WP_006117083.1\|981924_982638_-	hypothetical protein	NA	NA	NA	NA
WP_006117082.1\|982673_983711_-	hypothetical protein	NA	NA	NA	NA
WP_006117080.1\|983880_984336_-	hypothetical protein	NA	NA	NA	NA
WP_006117079.1\|984375_984813_-	hypothetical protein	NA	NA	NA	NA
WP_006117078.1\|984815_985970_-	DUF3383 family protein	H9C0W5	Aeromonas_phage	9.5e-29	34.2
WP_006117077.1\|985988_986561_-	hypothetical protein	NA	NA	NA	NA
WP_035354202.1\|986521_986902_-	hypothetical protein	NA	NA	NA	NA
WP_006117075.1\|986892_987399_-	DUF4054 domain-containing protein	H9C0W0	Aeromonas_phage	7.2e-13	44.0
WP_006117074.1\|987435_987753_-	hypothetical protein	H9C0V9	Aeromonas_phage	3.5e-10	38.4
WP_035354206.1\|987799_988837_-	DUF2184 domain-containing protein	A0A219YBB0	Aeromonas_phage	6.9e-79	46.7
WP_006117072.1\|988836_989337_-	hypothetical protein	A0A219YBF2	Aeromonas_phage	2.0e-31	48.1
WP_035354209.1\|989377_990379_-	DUF2213 domain-containing protein	A0A2R3UAL3	Myoviridae_environmental_samples	9.8e-30	36.4
WP_035354325.1\|990379_991756_-	DUF1073 domain-containing protein	A0A2R3UAL5	Myoviridae_environmental_samples	2.7e-86	44.0
WP_156100447.1\|991846_991987_-	hypothetical protein	NA	NA	NA	NA
WP_035354328.1\|992001_993054_+	rhodanese-related sulfurtransferase	NA	NA	NA	NA
WP_006117068.1\|993050_994505_-\|terminase	phage terminase large subunit	A0A1X9SGU8	Bradyrhizobium_phage	2.5e-106	46.0

DBSCAN-SWA_3

1308697 : 1368344

uncultured_Mediterranean_phage(20.0%)

transposase,holin,integrase,tRNA

attL 1356819:1356844|attR 1365363:1365388

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006116788.1\|1308697_1309774_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_035352785.1\|1309775_1310936_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	6.5e-94	50.8
WP_006116786.1\|1310948_1312049_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_035352782.1\|1312045_1312291_+	ribbon-helix-helix domain-containing protein	NA	NA	NA	NA
WP_035352779.1\|1312370_1313198_+	molecular chaperone DjlA	NA	NA	NA	NA
WP_026019323.1\|1313442_1314291_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_006116783.1\|1314318_1314942_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_006116782.1\|1314999_1315503_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_006116781.1\|1315626_1317306_-	energy-dependent translational throttle protein EttA	A0A2K9L0W2	Tupanvirus	3.2e-41	26.0
WP_006116780.1\|1317615_1318143_+	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	6.3e-44	51.2
WP_035352775.1\|1318304_1319123_+	dioxygenase	NA	NA	NA	NA
WP_006116778.1\|1319205_1319814_+	polyisoprenoid-binding protein	NA	NA	NA	NA
WP_035352772.1\|1320137_1320665_-	alkyl hydroperoxide reductase	NA	NA	NA	NA
WP_035352769.1\|1320868_1321411_-	peroxiredoxin	NA	NA	NA	NA
WP_035352767.1\|1321591_1322554_+	hydrogen peroxide-inducible genes activator	NA	NA	NA	NA
WP_003625637.1\|1322662_1322788_+	50S ribosomal protein L36	NA	NA	NA	NA
WP_006116774.1\|1322792_1323473_+	hypothetical protein	NA	NA	NA	NA
WP_006116773.1\|1323496_1324393_-	prephenate/arogenate dehydrogenase family protein	NA	NA	NA	NA
WP_050793154.1\|1324385_1325477_-	hypothetical protein	NA	NA	NA	NA
WP_035352761.1\|1325670_1326666_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_006116771.1\|1326676_1327873_+	glycosyltransferase	NA	NA	NA	NA
WP_006116770.1\|1327985_1328846_+	squalene synthase HpnC	NA	NA	NA	NA
WP_035352759.1\|1328944_1329823_+	presqualene diphosphate synthase HpnD	NA	NA	NA	NA
WP_035352757.1\|1329844_1331143_+	NAD(P)-binding protein	NA	NA	NA	NA
WP_006116767.1\|1331208_1333179_+	squalene--hopene cyclase	NA	NA	NA	NA
WP_035352754.1\|1333183_1333894_+	hypothetical protein	NA	NA	NA	NA
WP_035352845.1\|1333900_1334140_-	hypothetical protein	NA	NA	NA	NA
WP_006116766.1\|1334201_1335728_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_003625609.1\|1335737_1336649_-	HlyD family secretion protein	NA	NA	NA	NA
WP_035352748.1\|1336675_1336870_-	DUF1656 domain-containing protein	NA	NA	NA	NA
WP_006116765.1\|1336892_1337387_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_006116764.1\|1337520_1337946_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_003625602.1\|1337985_1338288_-	hypothetical protein	NA	NA	NA	NA
WP_006116763.1\|1338361_1339477_+	TOBE domain-containing protein	NA	NA	NA	NA
WP_035352745.1\|1339512_1340625_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_006116762.1\|1340606_1341044_+	hypothetical protein	NA	NA	NA	NA
WP_006116761.1\|1341040_1341496_+	YcgN family cysteine cluster protein	NA	NA	NA	NA
WP_035352842.1\|1341562_1342240_+	DUF45 domain-containing protein	NA	NA	NA	NA
WP_006116759.1\|1342696_1344235_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_006116758.1\|1344620_1345595_-	hypothetical protein	NA	NA	NA	NA
WP_035352739.1\|1345530_1346367_-	hypothetical protein	NA	NA	NA	NA
WP_139018871.1\|1346667_1348266_-	hypothetical protein	NA	NA	NA	NA
WP_100070290.1\|1348355_1348676_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_050793153.1\|1349032_1349881_-	hypothetical protein	NA	NA	NA	NA
WP_035352736.1\|1349877_1350591_-	hypothetical protein	NA	NA	NA	NA
WP_006116755.1\|1350787_1351363_+	recombinase family protein	A0A219YB42	Aeromonas_phage	1.3e-29	41.8
WP_139018870.1\|1351570_1352398_+	hypothetical protein	NA	NA	NA	NA
WP_139018869.1\|1353235_1355266_-	hypothetical protein	NA	NA	NA	NA
WP_035352727.1\|1355436_1356291_-	hypothetical protein	NA	NA	NA	NA
1356819:1356844	attL	NA	NA	NA	NA
WP_035351263.1\|1356933_1358307_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_035351269.1\|1358417_1358600_-	hypothetical protein	NA	NA	NA	NA
WP_006116749.1\|1359044_1360133_-	DUF3578 domain-containing protein	NA	NA	NA	NA
WP_035351267.1\|1361485_1362877_+\|integrase	site-specific integrase	A0A0U4JNS1	Bacillus_phage	4.3e-07	29.0
WP_100070289.1\|1363093_1364566_-	hypothetical protein	NA	NA	NA	NA
WP_035351265.1\|1365604_1366570_+\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
1365363:1365388	attR	NA	NA	NA	NA
WP_157772571.1\|1366903_1367293_-	hypothetical protein	NA	NA	NA	NA
WP_035352416.1\|1367252_1368344_-\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1563934 : 1571713

Pseudomonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006115701.1\|1563934_1564732_+	ParA family protein	Q8JL10	Natrialba_phage	1.1e-20	29.4
WP_006115700.1\|1564728_1565652_+	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	1.2e-13	35.7
WP_006115699.1\|1566664_1567234_-	recombinase family protein	M9Q1K0	Clostridium_phage	3.7e-26	45.0
WP_006115697.1\|1567461_1569372_-	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	1.7e-54	32.0
WP_035352976.1\|1569340_1570408_-	hypothetical protein	A0A0U4B0G9	Pseudomonas_phage	2.2e-19	41.7
WP_035352979.1\|1570394_1571006_-	hypothetical protein	NA	NA	NA	NA
WP_006115695.1\|1571002_1571713_-	phage antirepressor Ant	A0A160DFU1	Gordonia_phage	5.1e-33	35.0

DBSCAN-SWA_5

2305197 : 2327886

Burkholderia_virus(25.0%)

transposase,integrase

attL 2305508:2305567|attR 2326717:2327657

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096884287.1\|2305197_2306407_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	5.0e-97	64.0
2305508:2305567	attL	NA	NA	NA	NA
WP_096884288.1\|2306631_2306952_-	hypothetical protein	NA	NA	NA	NA
WP_006117393.1\|2307474_2308026_-	hypothetical protein	NA	NA	NA	NA
WP_035351308.1\|2308140_2308287_-\|transposase	transposase	NA	NA	NA	NA
WP_035353789.1\|2310612_2311851_+	hypothetical protein	NA	NA	NA	NA
WP_050793170.1\|2311853_2312411_+	CdiI family contact-dependent growth inhibition immunity protein	NA	NA	NA	NA
WP_050793169.1\|2312529_2313087_+	CdiI family contact-dependent growth inhibition immunity protein	NA	NA	NA	NA
WP_050793168.1\|2313205_2313763_+	CdiI family contact-dependent growth inhibition immunity protein	NA	NA	NA	NA
WP_035353722.1\|2313996_2314737_-	DUF4214 domain-containing protein	NA	NA	NA	NA
WP_035353730.1\|2314965_2316945_+	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	1.8e-35	30.8
WP_006115450.1\|2317161_2318772_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.7e-111	42.3
WP_012812355.1\|2318835_2319183_-	IS66 family insertion sequence element accessory protein TnpB	S5WJH4	Leptospira_phage	2.7e-11	46.8
WP_012812356.1\|2319179_2319539_-\|transposase	transposase	NA	NA	NA	NA
WP_035353735.1\|2320625_2321054_-	RidA family protein	NA	NA	NA	NA
WP_155006655.1\|2321180_2321474_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_157772574.1\|2321507_2321699_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_035353724.1\|2321749_2322046_+	prevent-host-death protein	NA	NA	NA	NA
WP_006117289.1\|2322042_2322426_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_006117288.1\|2323354_2323846_-	type II toxin-antitoxin system YhaV family toxin	NA	NA	NA	NA
WP_006117287.1\|2323848_2324181_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_035353727.1\|2324450_2324693_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_010511145.1\|2326854_2327886_+\|transposase	IS110 family transposase	NA	NA	NA	NA
2326717:2327657	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2399559 : 2410275

uncultured_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006116434.1\|2399559_2401140_-	hypothetical protein	B2ZYD9	Ralstonia_phage	4.3e-40	28.1
WP_006116435.1\|2401154_2401529_-	hypothetical protein	M4QRS4	Synechococcus_phage	2.4e-18	41.5
WP_035352442.1\|2401672_2403889_-	hypothetical protein	NA	NA	NA	NA
WP_006116437.1\|2404083_2405724_-	chaperonin GroEL	A0A219YK78	uncultured_virus	2.8e-175	62.0
WP_026019247.1\|2405779_2406073_-	co-chaperone GroES	A0A221S4G8	uncultured_virus	1.4e-21	58.1
WP_006116439.1\|2406283_2406952_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_003625755.1\|2407095_2407299_+	cold-shock protein	A0A218MMZ6	uncultured_virus	1.3e-13	51.5
WP_035352448.1\|2407317_2410275_-	ATP-dependent DNA helicase	A0A2P1N0K5	Streptomyces_phage	3.3e-09	32.6

DBSCAN-SWA_7

2777529 : 2820853

Burkholderia_virus(18.18%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096884248.1\|2777529_2778739_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.6e-97	64.0
WP_086898137.1\|2779108_2782276_+	DNA polymerase III subunit alpha	A0A291AVA6	Streptomyces_phage	2.3e-88	26.6
WP_086898136.1\|2782645_2783245_+	glutathione S-transferase	NA	NA	NA	NA
WP_086898135.1\|2783406_2785494_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_086898134.1\|2785570_2786488_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_157772577.1\|2786637_2787432_+	hypothetical protein	NA	NA	NA	NA
WP_123809137.1\|2788105_2788534_+	hypothetical protein	NA	NA	NA	NA
WP_096884303.1\|2789369_2789978_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_089179083.1\|2790002_2791188_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_157772578.1\|2791172_2791310_-	hypothetical protein	NA	NA	NA	NA
WP_086898780.1\|2791995_2793177_+	DUF932 domain-containing protein	A0A1V0DX75	Synechococcus_virus	1.7e-73	40.9
WP_086898779.1\|2793257_2793668_+	hypothetical protein	NA	NA	NA	NA
WP_086898778.1\|2794190_2795759_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-104	45.2
WP_019092242.1\|2795824_2796172_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.5e-33	59.8
WP_075594769.1\|2796168_2796552_-\|transposase	transposase	NA	NA	NA	NA
WP_086898777.1\|2796878_2797493_-	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_086898783.1\|2797493_2798048_-	hypothetical protein	NA	NA	NA	NA
WP_086898776.1\|2798314_2798590_-	HU family DNA-binding protein	M4SRV7	Rhodobacter_phage	1.1e-12	45.7
WP_086898775.1\|2798787_2803092_+	DEAD/DEAH box helicase family protein	A0A076FMQ0	Aureococcus_anophage	1.9e-29	25.4
WP_086898782.1\|2803091_2804153_+	DNA primase	NA	NA	NA	NA
WP_086898774.1\|2804467_2805403_+	DUF2493 domain-containing protein	NA	NA	NA	NA
WP_086898773.1\|2805561_2806137_+	hypothetical protein	NA	NA	NA	NA
WP_086898781.1\|2806676_2806892_+	hypothetical protein	NA	NA	NA	NA
WP_035378674.1\|2806910_2807234_+	DUF736 domain-containing protein	NA	NA	NA	NA
WP_086898661.1\|2807884_2808322_+	hypothetical protein	NA	NA	NA	NA
WP_086898671.1\|2808595_2809249_+	DUF2285 domain-containing protein	NA	NA	NA	NA
WP_123809135.1\|2809462_2809729_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157772579.1\|2809737_2810553_+	RepA replication protein	NA	NA	NA	NA
WP_096884304.1\|2810806_2811496_+	site-specific DNA-methyltransferase	O03956	Myxococcus_phage	2.7e-55	51.7
WP_096884248.1\|2811547_2812757_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.6e-97	64.0
WP_086898665.1\|2812854_2813331_+	DUF2840 domain-containing protein	NA	NA	NA	NA
WP_086898666.1\|2813327_2813957_+	S26 family signal peptidase	NA	NA	NA	NA
WP_086898667.1\|2814011_2814353_+	DUF736 domain-containing protein	NA	NA	NA	NA
WP_086898668.1\|2814349_2814550_+	hypothetical protein	NA	NA	NA	NA
WP_086898669.1\|2814549_2815215_+	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	6.5e-14	43.8
WP_035353780.1\|2815211_2815466_+	hypothetical protein	NA	NA	NA	NA
WP_035353783.1\|2815462_2817208_+	DUF3363 domain-containing protein	NA	NA	NA	NA
WP_156100441.1\|2819257_2819410_+	hypothetical protein	NA	NA	NA	NA
WP_096884305.1\|2819467_2820853_+\|transposase	IS1380 family transposase	A0A1X9I6F6	Streptococcus_phage	5.5e-31	29.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP023660

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 16090

Rhodobacter_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039891754.1\|406_676_-	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_006116374.1\|672_948_-	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_139018868.1\|2295_2670_+	hypothetical protein	NA	NA	NA	NA
WP_081461445.1\|2683_3016_+	hypothetical protein	NA	NA	NA	NA
WP_006116376.1\|3071_3476_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_039891761.1\|3788_4211_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_039891762.1\|4207_4465_-	plasmid stabilization protein	NA	NA	NA	NA
WP_081461446.1\|4563_4818_-	hypothetical protein	NA	NA	NA	NA
WP_039891763.1\|4902_5166_-	hypothetical protein	NA	NA	NA	NA
WP_006116378.1\|6071_7127_+	replication initiator protein A	A0A0K1Y6J9	Rhodobacter_phage	3.0e-77	47.4
WP_006116379.1\|7166_7424_-	hypothetical protein	NA	NA	NA	NA
WP_039891769.1\|7451_8111_-	ParA family protein	B0ZSI1	Halomonas_phage	6.5e-14	27.9
WP_039891771.1\|8284_8881_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	1.5e-14	34.4
WP_006116383.1\|9045_9636_-	recombinase family protein	A0A1W5LU24	Ralstonia_phage	1.1e-25	41.2
WP_035352425.1\|12412_13027_-	recombinase family protein	E5FFF9	Burkholderia_phage	9.2e-39	50.8
WP_096884248.1\|14879_16090_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.6e-97	64.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP023658

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP023657

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP023660

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection