CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP023707	Edwardsiella tarda strain KC-Pc-HB1 plasmid pEh-Pc1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP023706	Edwardsiella tarda strain KC-Pc-HB1 chromosome, complete genome	1 crisprs	cas3,cas2,DinG,DEDDh,csa3,RT	1	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP023706_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP023706_1

2707497-2707645

Orphan

Consensus_repeat	Method
ATCCTGCACGACCCACCATTCTCTCGGTGAAAAATCGGTGTTTAGCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP023706_1

>merge|NZ_CP023706|1|2707497-2707645|CRISPRCasFinder
ATCCTGCACGACCCACCATTCTCTCGGTGAAAAATCGGTGTTTAGCGTGAAGGATAACATCGCGTAGCGATGGCCCATTAGGGCGAGGCATCAGCCGAGTCATCCTGCACGACCCACCATTCTCTCGGTGAGAAATCGGTGTTTAGCGT

>NZ_CP023706|1|1|2707497-2707645|CRISPRCasFinder
ATCCTGCACGACCCACCATTCTCTCGGTGAAAAATCGGTGTTTAGCGT	GAAGGATAACATCGCGTAGCGATGGCCCATTAGGGCGAGGCATCAGCCGAGTC
ATCCTGCACGACCCACCATTCTCTCGGTGAGAAATCGGTGTTTAGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP023706.1\|WP_005288888.1\|2701977_2702400_+\|colicin-uptake-protein-TolR	unknown	unknown	gnl\|CDD\|236824
NZ_CP023706.1\|WP_005294328.1\|2710676_2712056_+\|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl\|CDD\|273267
NZ_CP023706.1\|WP_005288863.1\|2713128_2714286_-\|galactokinase	unknown	unknown	gnl\|CDD\|179937
NZ_CP023706.1\|WP_097364435.1\|2712088_2713135_-\|galactose-1-epimerase	unknown	unknown	gnl\|CDD\|182931
NZ_CP023706.1\|WP_097364437.1\|2715332_2716376_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|182639
NZ_CP023706.1\|WP_097364436.1\|2714305_2715349_-\|galactose-1-phosphate-uridylyltransferase	unknown	unknown	gnl\|CDD\|236963
NZ_CP023706.1\|WP_005295382.1\|2702535_2703732_+\|cell-envelope-integrity-protein-TolA	unknown	unknown	gnl\|CDD\|236545
NZ_CP023706.1\|WP_097364438.1\|2716581_2717397_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP023706.1\|WP_005294325.1\|2709617_2710370_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184516
NZ_CP023706.1\|WP_005288881.1\|2705218_2705731_+\|peptidoglycan-associated-lipoprotein-Pal	unknown	unknown	gnl\|CDD\|182744
NZ_CP023706.1\|WP_005288883.1\|2703879_2705172_+\|Tol-Pal-system-protein-TolB	unknown	unknown	gnl\|CDD\|235143
NZ_CP023706.1\|WP_005288876.1\|2708503_2709568_+\|3-deoxy-7-phosphoheptulonate-synthase-AroG	unknown	unknown	gnl\|CDD\|236435
NZ_CP023706.1\|WP_005295375.1\|2700880_2701285_+\|tol-pal-system-associated-acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|182742
NZ_CP023706.1\|WP_035594717.1\|2701281_2701965_+\|Tol-Pal-system-protein-TolQ	unknown	unknown	gnl\|CDD\|182743
NZ_CP023706.1\|WP_005288903.1\|2699170_2700310_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|184965
NZ_CP023706.1\|WP_005288900.1\|2700329_2700443_+\|cytochrome-bd-I-oxidase-subunit-CydX	unknown	unknown	gnl\|CDD\|227227
NZ_CP023706.1\|WP_035595147.1\|2700442_2700736_+\|cyd-operon-protein-YbgE	unknown	unknown	gnl\|CDD\|236721
NZ_CP023706.1\|WP_005288848.1\|2718553_2718697_+\|multidrug-efflux-pump-associated-protein,-AcrZ-family	unknown	unknown	gnl\|CDD\|371231
NZ_CP023706.1\|WP_005295388.1\|2705754_2706540_+\|cell-division-protein-CpoB	unknown	unknown	gnl\|CDD\|182745
NZ_CP023706.1\|WP_005288851.1\|2717540_2718332_-\|molybdenum-dependent-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182640

Protein	Function_ID	Function_description	E-value
NZ_CP023706.1\|WP_005288888.1\|2701977_2702400_+\|colicin-uptake-protein-TolR	gnl\|CDD\|236824	PRK11024, PRK11024, colicin uptake protein TolR; Provisional.	9.6156e-94
NZ_CP023706.1\|WP_005294328.1\|2710676_2712056_+\|DASS-family-sodium-coupled-anion-symporter	gnl\|CDD\|273267	TIGR00785, Uncharacterized_transporter_HI_0020, anion transporter. The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds].	3.11957e-89
NZ_CP023706.1\|WP_005288863.1\|2713128_2714286_-\|galactokinase	gnl\|CDD\|179937	PRK05101, PRK05101, galactokinase; Provisional.	0
NZ_CP023706.1\|WP_097364435.1\|2712088_2713135_-\|galactose-1-epimerase	gnl\|CDD\|182931	PRK11055, galM, galactose-1-epimerase; Provisional.	0
NZ_CP023706.1\|WP_097364437.1\|2715332_2716376_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|182639	PRK10675, PRK10675, UDP-galactose-4-epimerase; Provisional.	0
NZ_CP023706.1\|WP_097364436.1\|2714305_2715349_-\|galactose-1-phosphate-uridylyltransferase	gnl\|CDD\|236963	PRK11720, PRK11720, UDP-glucose--hexose-1-phosphate uridylyltransferase.	0
NZ_CP023706.1\|WP_005295382.1\|2702535_2703732_+\|cell-envelope-integrity-protein-TolA	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	3.12092e-64
NZ_CP023706.1\|WP_097364438.1\|2716581_2717397_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.15382e-14
NZ_CP023706.1\|WP_005294325.1\|2709617_2710370_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184516	PRK14115, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	0
NZ_CP023706.1\|WP_005288881.1\|2705218_2705731_+\|peptidoglycan-associated-lipoprotein-Pal	gnl\|CDD\|182744	PRK10802, PRK10802, peptidoglycan-associated lipoprotein Pal.	2.98073e-114
NZ_CP023706.1\|WP_005288883.1\|2703879_2705172_+\|Tol-Pal-system-protein-TolB	gnl\|CDD\|235143	PRK03629, tolB, Tol-Pal system protein TolB.	0
NZ_CP023706.1\|WP_005288876.1\|2708503_2709568_+\|3-deoxy-7-phosphoheptulonate-synthase-AroG	gnl\|CDD\|236435	PRK09261, PRK09261, phospho-2-dehydro-3-deoxyheptonate aldolase; Validated.	0
NZ_CP023706.1\|WP_005295375.1\|2700880_2701285_+\|tol-pal-system-associated-acyl-CoA-thioesterase	gnl\|CDD\|182742	PRK10800, PRK10800, acyl-CoA thioesterase YbgC; Provisional.	9.23262e-89
NZ_CP023706.1\|WP_035594717.1\|2701281_2701965_+\|Tol-Pal-system-protein-TolQ	gnl\|CDD\|182743	PRK10801, PRK10801, Tol-Pal system protein TolQ.	4.41009e-161
NZ_CP023706.1\|WP_005288903.1\|2699170_2700310_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|184965	PRK15003, PRK15003, cytochrome d ubiquinol oxidase subunit II.	0
NZ_CP023706.1\|WP_005288900.1\|2700329_2700443_+\|cytochrome-bd-I-oxidase-subunit-CydX	gnl\|CDD\|227227	COG4890, COG4890, Predicted outer membrane lipoprotein [Function unknown].	3.28762e-07
NZ_CP023706.1\|WP_035595147.1\|2700442_2700736_+\|cyd-operon-protein-YbgE	gnl\|CDD\|236721	PRK10588, PRK10588, hypothetical protein; Provisional.	5.94454e-53
NZ_CP023706.1\|WP_005288848.1\|2718553_2718697_+\|multidrug-efflux-pump-associated-protein,-AcrZ-family	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	2.22028e-17
NZ_CP023706.1\|WP_005295388.1\|2705754_2706540_+\|cell-division-protein-CpoB	gnl\|CDD\|182745	PRK10803, PRK10803, tol-pal system protein YbgF; Provisional.	1.49582e-147
NZ_CP023706.1\|WP_005288851.1\|2717540_2718332_-\|molybdenum-dependent-transcriptional-regulator	gnl\|CDD\|182640	PRK10676, PRK10676, DNA-binding transcriptional regulator ModE; Provisional.	3.17239e-171

>NZ_CP023706.1|WP_005295388.1|2705754_2706540_+|cell-division-protein-CpoB
MSSNFRRHVMALSLLVGVAAPWAATAQAPISSVGSGSVEDRVTSLERITNAQGQLLTQLQQQLSDNQRDIDTLRGQIQENQYQLNQIVERQKQIYQQIDSLSSGNAAQGNTPAASAQPADSTAPAASAPAAAPQAAAASGDANTDYNRAVDLVLVKKQNDQAISAFQTFIKQYPDSTYQPNANYWLGQLYYSKGKKDDAAYYYAVVVKNYPKSPKAPESMYKVGVIMQEKGQSDKAHAVFQQVLKQYPNSEAAKLAQKRLG
>NZ_CP023706.1|WP_005288881.1|2705218_2705731_+|peptidoglycan-associated-lipoprotein-Pal
MQLNKVLKGLMLVLPIMAVAACSSKKNTNDDQSGMGVGANGMENSSSNLSSEEQARLQMQELQKNNIVYFGLDKYDVTPEYMQELDAHAAFLRNNPSYKVTVEGHTDERGTPEYNIALGERRANAVKMYLQGKGVSADQIDIVSYGKEKPAVLGHDEAAYAKNRRAVLVY
>NZ_CP023706.1|WP_005288883.1|2703879_2705172_+|Tol-Pal-system-protein-TolB
MKQAFRLMVGLLVLWASVLHAEVRIVITQGVDSARPIGVVPFKWMGPGAAPENIGGIIAADLRNSGKFNPIDASRMPQQPATAAEVTPAAWTALGIDAVVVGQVQPGADGSYLVSYQLVDTSGNPGSVLAQNQYKVTKQWLRYAAHTASDEVFEKLTGIKGAFRTRIAYVVQTNGGQFPYELRVADYDGYNQFVVHRSAEPLMSPAWSSDGSKLAYVTFESGRSALVIQTLSNGAIRQVASFPRHNGSPAFSPDGTKLAFALSKTGSLNLYVMDLASGAIRQVTDGRSNNTEPSWFPDSQNLAFTSDQAGRPQIYKININGGAAQRLTWEGAQNQDAEVSPDGKFLVMVSSNAGAQHIAKLDLGTNATQVLTDTFLDETPSIAPNGTMVIYSSTQGLGSVLQLVSIDGRFKARLPATDGQVKFPAWSPYL
>NZ_CP023706.1|WP_005295382.1|2702535_2703732_+|cell-envelope-integrity-protein-TolA
MGNATEQKDKLNRSVIISVILHIVLIGLLVWGSMLQDNPMSEGGDGGGGGSAIDAVMVDPNAVVQQYNRQQEQQNAAQRAEQQRQKQAEKQAQEMQRKQAEEQQRLKALEKERLQAQEDARKAAEEAKQAAEAAKKQAAEEAKQAAEEAKKQAALAIQQAKEEAAKAAAAAKKQAEEEVKKAAAEAKKQAEEAAKKQAAEEAKKQAAAAAKAKAAAEAKAAAEAKAAAEAKAKAETEAKAKADAKKAAEAKKKAAAAAAAKQADEVDDLFGGLASSKNAPKGTANGGTPGNSGKAGPAGKGNSKTSGASGAEISGYADQIKSAIMAKFYTDPSYTGKTCDLRIKLAPDGLLLDVKAEGGDPALCQAALSAARQARYPKPPSEAVYQVFKNAPVVFQPQ
>NZ_CP023706.1|WP_005288888.1|2701977_2702400_+|colicin-uptake-protein-TolR
MARLGGRRDLKSEINIVPLLDVLLVLVLIFMATAPIITQSVEVDLPDATDSKTVSSNDHPPVIVEVSGVGQYAVVVNHNRMEQLPPEQVIAEAQAQLKADPKTVFLIGGAKEVPYDEIIKALNLLHQAGVTSVGLMTQPI
>NZ_CP023706.1|WP_035594717.1|2701281_2701965_+|Tol-Pal-system-protein-TolQ
MTDMNILDLFLKASVLVKLIMLVLICFSVASWAIIIQRTRILNAATRDAEAFEDKFWSGIELSRLYQESQTRRDTLNGSEQIFYAGFKEFARLHRMNSHATEGVIEGASRAMRISLNREVEALETHIPFLGTVGSISPYIGLFGTVWGIMHAFIGLGAVKQATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNLRVNKLEQNYENFMEEFIAILHRQAFAADGK
>NZ_CP023706.1|WP_005295375.1|2700880_2701285_+|tol-pal-system-associated-acyl-CoA-thioesterase
MSHMVFRWPVRVYFEDTDAGGVVYHARYVAFYERARTEMLRQHHFSQQQLLTEHVAFAVRRMTVDYLAPARLDDLLVVESEISALRGASLTFAQRIVNSEGLVLSRADVLIACIDQNLMKPIALPKSIVAEFKQ
>NZ_CP023706.1|WP_035595147.1|2700442_2700736_+|cyd-operon-protein-YbgE
MTGLADKLYNLMDKGPLRALSLILALVLAGCIFWDPTRFAAKTSALEIWQGLLIMWAVCCGVVHGVGFRPQRAWWRAFFSPLPALIVLAAGLGFFFL
>NZ_CP023706.1|WP_005288900.1|2700329_2700443_+|cytochrome-bd-I-oxidase-subunit-CydX
MWYFAWVLGTLMACFFAIITAMAIENSEAKKAAQDGK
>NZ_CP023706.1|WP_005288903.1|2699170_2700310_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MFEYEVLRFVWWLLVGVLLIGFAITDGFDMGVGILSRILGKTDTERRVMINAIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLSALFFRPVGFDYRSKITDPRWRNMWDWGIFIGSFVPALVFGVAFGNLLQGVPFHIDEYLRLFYTGNFFQLLNPFGLLAGVVSLTMLLVQGAAYLQMKTAGELRLRARAATQICALIMMVAFLLAGIWVVKGIDGYIVTSALDYAAPSNPLHKEVAHQAGAWLVNFEAHPILWLIPALGVVLPLLTILTSRLDRCGWAFLFSSLTIACVILTAGITMFPFVMPSITNPSMSLTMWDATSSLLTLKVMTVVAIVFVPIVLLYTIWSYYKMFGRLDKNYIENNNHSLY
>NZ_CP023706.1|WP_005288876.1|2708503_2709568_+|3-deoxy-7-phosphoheptulonate-synthase-AroG
MSYQNDDLRINQIQELLPPVALLEAFPASDSAAQTVAQTRNAIHRILQAQDDRLLVIIGPCSIHDPLAAKEYASRLLALRHALAGELEIVMRVYFEKPRTTVGWKGLINDPHMDGSYRINDGLRSARRLLLEINDSGMPTAGEFLDMITPQYLADLMSWGAIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHSAIVSTSGNGDCHIILRGGRQPNYRADDVQAVKAGLSQAGLPAQVMIDFSHANSSKQFQRQMVVCEDVCGQLASGERAIMGVMIESNLVEGNQSPDNGATLRYGQSVTDACIGWEDSERALRQLAQAVRARRAHSVA
>NZ_CP023706.1|WP_005294325.1|2709617_2710370_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MAVTKLVLVRHGESEWNKENRFTGWTDVELSDKGRQEARAAGRLLQEQGFSFDFAYTSVLKRAIHTLWHILDEIDQPWLAVEKSWKLNERHYGALQGLNKAETAQKYGDEQVKLWRRAFAITPPALTPQDERYPGHDPRYAALSSDELPLTESLATTIERVIPYWQQQIMPRIAAGERVIIAAHGNSLRALVKHLDQISEAEIVELNIPTGVPLVYEFDEQMRPLRHYYLGDAAEIAARQAAVANQGKAG
>NZ_CP023706.1|WP_005294328.1|2710676_2712056_+|DASS-family-sodium-coupled-anion-symporter
MDATPLTAAMASPPSQRGLLIMALDIALLVILLQILPFDEKANTGLALTIFVGVLWLTEAVHVTITALLIPLLAIGFGLLDAAGALKSFANPTIFLFFGGFVLATALHVQGLDRLIANQLLLLAGGRMATAVLMLFSVTAALSMWISNTATAAMMLPLALGILTNLDPVRERNTYVFLLLGIAYSASIGGLGTLVGSPPNAIAAAQLGIDFLTWMKYGIPVMVVMMPLMMGLLYLLLRPNLQHKVTLHVEPLEWTASRVIALLIFALTVFGWIFSSQISAMLGGIKQFDTLVAVGAAVLIGASGVASWDQIQRNTEWGVLMLFGGGLTLSLILEGSGASAILAHGMADIFGQSHWFIILLAVAAFIIFLTEFTSNTASAALLVPVFATVAKALGMPESLLTLVIGIGASCAFMLPVATPPNAIVFGSGHIRQQEMVRVGFWLNLVSIFALSLFAWLFWR
>NZ_CP023706.1|WP_097364435.1|2712088_2713135_-|galactose-1-epimerase
MLSDNLERAPDGDPFQFTALHNARGTTLLLMDWGASWLSCRLALGGGQAREVLLGCRRASQYPEQQAFLGATIGRYANRIANAAYLDHGQRVALLPSQGVNQLHGGPEGFDKRRWQRVTHDPHSVTYRLHSPDGDQGYPGNLTVETRYTLDDEDRVTIDWQARVDRTCPVGLTNHAYFNLGGDGQADALMQQLQLNADEYLPVDEQGIPCAPLRTVAGSGMDFRQSKTLRGDLLRDVDQRRVKGYDHAFLLQPRCRDGAYPAATLRADDGRVSLQVYTNAPTLQLYSGNYLAGTPDRQGGHYADYAGVALECAFLPDSPNHPEWPQPRCLLQPGETYHAFAQYHFHVA
>NZ_CP023706.1|WP_005288863.1|2713128_2714286_-|galactokinase
MRLHDLTRLTREIFTREFGYAPTCCVQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAARPDRQVRVIAADYANQQDSFSLDAPIVAHDSMMWSNYVRGVIKHLQQRCDTIGGVDMVISGNVPQGAGLSSSAALEVAVGQALQALYQLPLDGVALALNGQEAENRFVGCNCGIMDQLISALGQAQHALLIDCRSLATQAVPLPAEAAVVIINSNVKRGLVDSEYNTRRQQCEEAARFFAVPALRDVTPERFAAEAHALPALTARRARHVISENARTVAAAEALAAGDLGRMGELMAASHASMRDDFAITVPPIDTLVEIVKGVIGDRGGVRMTGGGFGGCVVALMPHALVEAVRSAVARDYPARTGLHESFYVCQPSAGASVC
>NZ_CP023706.1|WP_097364436.1|2714305_2715349_-|galactose-1-phosphate-uridylyltransferase
MTTTFNPVDHPHRRYNPLNEQWVLVSPHRAKRPWQGAQETPASTQLPAHDPDCYLCPGNLRVTGDRNPDYRTTHVFTNDFAALMPDTPDAPSSDDVLMRSASARGTSRVICFSPDHSKTLPQLSLAALEAVIATWQSQSAELGRRYPWVQVFENKGAAMGCSNPHPHGQIWANSFLPNEAAREDRLQRDYFLRHHRPLLLDYVQRELADGSRTVVETAHWLAVVPYWAAWPFETLLLPKQPLRRLPEIDAAQRSDLAVAIKKLTSRYDNLFHCAFPYSMGWHGAPFDQVDTDHWLLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTPEQAAERLRAVSDIHFSEA
>NZ_CP023706.1|WP_097364437.1|2715332_2716376_-|UDP-glucose-4-epimerase-GalE
MIVLVTGGSGYIGSHTCLQLLQAGHTPVIVDNLCNSKVSVLDRIAALGGTRPVLYQGDVRDRALLTRIFAEHAIDAVIHFAGLKAVGESVQRPLAYYDNNVGGTLVLLEVMQQAGVHNIIFSSSATVYGDQPQVPYVEAMPTGMPSSPYGRSKLMVEQILQDLQHASPAWSVTLLRYFNPVGAHPSGTMGEDPQGIPNNLMPYISQVAIGRRDSLAIFGNDYPTPDGTGVRDYIHVMDLADGHLAALQAKCHQPGVHIYNLGAGVGYSVLQVVDAFSQACGKAVPYHFAPRRAGDLPAYWADAAKAERELGWRVHHSLAQMAEDTWRWQSRNPNGYPQKECGDDDDL
>NZ_CP023706.1|WP_097364438.1|2716581_2717397_-|CPBP-family-intramembrane-metalloprotease
MWEILLLPALLLAWAPRAAFLSAAVAVALLAYQGLIAPLAAALLALMALVLYLRGRLTLSTPWRALSEIGLVAAILTLYLHHFPGFHNPLLLDKVRVGAHSAPFTLYANLDKALAPLLLLALYPTLLRRPDAQRVPAWRYGALLLSLPALLLLAVALGGLRIEPHWPHWLLTFSLLNLLFVSLPEEALFRGYLQQRLSAWFGPWVALLLAALLFGLLHLAGGPLLVLFATLAGGIYGLAWQWSGRLWVAVLFHFALNMLHLLFFTYPLYRP
>NZ_CP023706.1|WP_005288851.1|2717540_2718332_-|molybdenum-dependent-transcriptional-regulator
MQADILLTLKLQDRLFADPRRIELLKQVRHTGSISQGAKLAGISYKSAWDAINEMNQLADEEIVARATGGKGGGGARLTRYGERLIALYDLLGQIQQKAFDVLKSDELPLDSLLAAIARFSLQTSARNQFFATVIERDDEAVQQHLLLRLADGKTQLRAAVTAQSAQRLALHPGKEVLVLIKAPWIRLSTDPALSGAADNALSGRVSHIQAGSDNSEVLLTLPSGETLCATVDNRTMSQLQLSLGMSVNALFNADRVIVATLA
>NZ_CP023706.1|WP_005288848.1|2718553_2718697_+|multidrug-efflux-pump-associated-protein,-AcrZ-family
MFELLKSLVVAAIMVPVVMAVILGLIWGMGELCNLISAWGHPEEKES

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP023706_1	1.1\|2707545\|53\|NZ_CP023706\|CRISPRCasFinder	2707545-2707597	53	NZ_CP023706.1	2706820-2706872	2	0.962
NZ_CP023706_1	1.1\|2707545\|53\|NZ_CP023706\|CRISPRCasFinder	2707545-2707597	53	NZ_CP023706.1	2707044-2707096	2	0.962

1. spacer 1.1|2707545|53|NZ_CP023706|CRISPRCasFinder matches to position: 2706820-2706872, mismatch: 2, identity: 0.962

gaaggataacatcgcgtagcgatggcccattagggcgaggcatcagccgagtc	CRISPR spacer
gaaggataacatcgcgtagcgatggcccgttagggcgaggcgtcagccgagtc	Protospacer
****************************.************.***********

2. spacer 1.1|2707545|53|NZ_CP023706|CRISPRCasFinder matches to position: 2707044-2707096, mismatch: 2, identity: 0.962

gaaggataacatcgcgtagcgatggcccattagggcgaggcatcagccgagtc	CRISPR spacer
gaaggataacatcgcgtagcgatggcccgttagggcgaggcgtcagccgagtc	Protospacer
****************************.************.***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

16138 : 59736

Enterobacteria_phage(42.86%)

terminase,head,capsid,lysis,tail,portal

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_097363877.1\|16138_16726_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	6.0e-88	84.0
WP_157757856.1\|16755_17607_+	hypothetical protein	K7P7Q7	Enterobacteria_phage	3.2e-13	39.2
WP_097363879.1\|17606_18188_+\|tail	tail fiber assembly protein	Q9MCR5	Enterobacteria_phage	2.9e-34	44.8
WP_097363880.1\|18217_18745_-\|tail	tail fiber assembly protein	A0A222YWC2	Escherichia_phage	3.6e-31	43.5
WP_097363881.1\|18744_21462_-\|tail	prophage tail fiber N-terminal domain-containing protein	Q1MVL8	Enterobacteria_phage	6.6e-121	40.6
WP_097363882.1\|21534_22197_-	Ail/Lom family outer membrane beta-barrel protein	A0A0N7C1B9	Escherichia_phage	4.7e-12	29.6
WP_097363883.1\|22249_23251_-	hypothetical protein	NA	NA	NA	NA
WP_097363884.1\|23247_26367_-	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	57.5
WP_097363885.1\|26440_27091_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	9.7e-71	62.3
WP_097363886.1\|26988_27726_-	C40 family peptidase	S5MQI8	Escherichia_phage	1.2e-104	71.6
WP_097363887.1\|27731_28433_-\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	7.7e-90	67.2
WP_005293572.1\|28659_28989_-\|tail	phage tail protein	A0A291AWW9	Escherichia_phage	4.0e-33	59.6
WP_097363888.1\|28988_31832_-\|tail	phage tail tape measure protein	A5LH38	Enterobacteria_phage	5.3e-81	36.5
WP_097363889.1\|31821_32145_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	2.3e-12	40.6
WP_097364682.1\|32153_32549_-\|tail	phage minor tail protein G	M9NZD7	Enterobacteria_phage	1.5e-05	35.7
WP_097363890.1\|32611_33382_-\|tail	phage tail protein	K7P6G8	Enterobacteria_phage	1.3e-37	42.9
WP_005285669.1\|33385_33799_-	hypothetical protein	Q9EYD7	Enterobacteria_phage	3.0e-17	36.9
WP_005293565.1\|33795_34371_-\|tail	phage tail protein	NA	NA	NA	NA
WP_005285665.1\|34379_34739_-\|tail	tail attachment protein	E4WL27	Enterobacteria_phage	1.7e-24	48.7
WP_068871537.1\|34750_35134_-	hypothetical protein	NA	NA	NA	NA
WP_005285662.1\|35190_36219_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	6.1e-112	58.9
WP_005285660.1\|36287_36626_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.4e-20	55.4
WP_097363891.1\|36658_38146_-	S49 family peptidase	O64320	Escherichia_phage	5.2e-104	54.1
WP_097363892.1\|38135_39728_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	1.6e-188	63.3
WP_097363893.1\|39724_39934_-	gpW family protein	A0A2R9YJL2	Escherichia_phage	3.4e-09	45.9
WP_097363894.1\|39936_41856_-\|terminase	phage terminase large subunit family protein	O64317	Escherichia_phage	6.3e-251	64.0
WP_005285642.1\|41827_42334_-\|terminase	terminase small subunit	O64316	Escherichia_phage	4.9e-38	50.0
WP_097364683.1\|43068_43473_-	hypothetical protein	NA	NA	NA	NA
WP_157757857.1\|43576_43834_-	hypothetical protein	Q8SBD8	Shigella_phage	3.6e-21	64.3
WP_097363896.1\|44553_45072_-	KilA-N domain-containing protein	A0A1V0E5P7	Salmonella_phage	4.0e-59	68.6
WP_005293540.1\|45339_45555_-	hypothetical protein	K7PJU3	Enterobacteria_phage	5.0e-16	56.1
WP_157757858.1\|45587_45830_-	hypothetical protein	K7PKT0	Enterobacteria_phage	5.8e-05	34.2
WP_005285628.1\|46028_46568_-	lysozyme	A0A2R2Z343	Escherichia_phage	9.2e-75	73.7
WP_116605073.1\|46573_46846_-\|lysis	lysis protein	Q7Y3V4	Yersinia_phage	1.8e-10	38.9
WP_097363897.1\|47031_47310_+	hypothetical protein	NA	NA	NA	NA
WP_097363898.1\|48156_48927_-	antitermination protein	Q76H66	Enterobacteria_phage	2.6e-67	50.0
WP_097363899.1\|48946_49990_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.8e-64	40.2
WP_097363900.1\|49989_50208_-	LexA family transcriptional regulator	U5P451	Shigella_phage	6.6e-08	44.1
WP_097363901.1\|50204_50891_-	Rha family transcriptional regulator	A0A1W6DWH5	Salmonella_phage	9.4e-24	67.9
WP_097363902.1\|51196_52042_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_097363903.1\|52071_52440_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_097363905.1\|52794_53532_-	DNA replication protein	A0A0F6TJ71	Escherichia_coli_O157_typing_phage	1.1e-46	46.5
WP_097363906.1\|53528_54437_-	conserved phage C-terminal domain-containing protein	A0A1V0E8B1	Vibrio_phage	7.1e-11	45.5
WP_097363907.1\|54433_54613_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_097363908.1\|54799_55342_-	hypothetical protein	K7PJS5	Enterobacterial_phage	6.1e-26	50.4
WP_078000140.1\|55435_55666_-	Cro/Cl family transcriptional regulator	K7PHA1	Enterobacteria_phage	9.4e-21	65.8
WP_097363909.1\|55767_56439_+	LexA family transcriptional repressor	A0A077KGZ5	Edwardsiella_phage	5.7e-74	78.3
WP_097364684.1\|56446_56878_+	hypothetical protein	C6ZR46	Salmonella_phage	7.6e-64	84.1
WP_097363910.1\|56864_57203_+	hypothetical protein	C6ZR45	Salmonella_phage	8.1e-29	72.3
WP_097363911.1\|57838_58066_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_097363912.1\|58078_58624_-	DUF2975 domain-containing protein	NA	NA	NA	NA
WP_097363913.1\|58975_59326_+	hypothetical protein	NA	NA	NA	NA
WP_157757859.1\|59511_59736_+	hypothetical protein	I6PDF6	Cronobacter_phage	5.2e-08	64.4

DBSCAN-SWA_2

474947 : 481378

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_097364009.1\|474947_476012_-	glycoside hydrolase family 99-like domain-containing protein	A0A1V0SDW6	Indivirus	6.1e-30	28.5
WP_097364690.1\|476001_476511_-	CatB-related O-acetyltransferase	A0A1J0F9G1	Only_Syngen_Nebraska_virus	2.2e-06	59.5
WP_097364010.1\|476686_477889_-	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_097364011.1\|477885_478434_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	1.0e-57	62.1
WP_097364012.1\|478477_479359_-	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	6.9e-104	64.1
WP_077999255.1\|479399_480290_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	3.7e-28	36.1
WP_097364013.1\|480289_481378_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.1e-98	52.3

DBSCAN-SWA_3

797839 : 808409

Enterobacteria_phage(85.71%)

integrase,transposase

attL 799644:799657|attR 815852:815865

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_097364082.1\|797839_798534_-\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	1.9e-120	88.3
WP_097364083.1\|799020_801357_-	toprim domain-containing protein	Q7M2A8	Enterobacteria_phage	0.0e+00	80.1
799644:799657	attL	NA	NA	NA	NA
WP_097364084.1\|801371_801692_-	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_045425703.1\|801688_801916_-	hypothetical protein	NA	NA	NA	NA
WP_097364085.1\|801912_802464_-	ash family protein	Q7M2A7	Enterobacteria_phage	5.2e-33	69.4
WP_097364086.1\|802460_802727_-	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	8.9e-31	70.5
WP_097364087.1\|803299_804052_+	glycoprotein 3	Q7M2A2	Enterobacteria_phage	1.4e-44	43.8
WP_071881907.1\|804048_804291_+	ogr/Delta-like zinc finger family protein	Q7M294	Enterobacteria_phage	3.8e-20	59.5
WP_097364088.1\|804305_804881_+	phage polarity suppression protein	NA	NA	NA	NA
WP_097364695.1\|805197_806307_-	hypothetical protein	NA	NA	NA	NA
WP_157757867.1\|806311_807229_-	hypothetical protein	NA	NA	NA	NA
WP_097364089.1\|807233_808409_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.1e-144	62.0
815852:815865	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1179532 : 1243137

Cronobacter_phage(43.24%)

terminase,head,capsid,integrase,plate,tRNA,tail,holin,portal

attL 1185753:1185803|attR 1216659:1216709

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047060505.1\|1179532_1180558_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	6.6e-106	57.7
WP_005295814.1\|1180771_1180987_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_035597148.1\|1181177_1182926_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	2.7e-75	36.7
WP_005281642.1\|1183161_1185003_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	8.3e-35	33.7
WP_068871231.1\|1185091_1185586_-	G/U mismatch-specific DNA glycosylase	NA	NA	NA	NA
1185753:1185803	attL	NA	NA	NA	NA
WP_097364147.1\|1186404_1188144_-	hypothetical protein	F1BUJ7	Cronobacter_phage	1.6e-120	50.1
WP_097364148.1\|1188121_1188706_-	hypothetical protein	A5X9J7	Aeromonas_virus	3.2e-33	52.2
WP_097364149.1\|1188702_1189572_-	hypothetical protein	Q94MX8	Haemophilus_virus	7.0e-24	33.5
WP_097364150.1\|1189579_1190026_-\|tail	tail fiber assembly protein	A0A2P1JUG3	Erwinia_phage	1.8e-15	59.0
WP_097364151.1\|1192427_1193033_-	hypothetical protein	F1BUK5	Cronobacter_phage	2.7e-59	56.1
WP_097364152.1\|1193025_1194213_-\|plate	baseplate J/gp47 family protein	F1BUK6	Cronobacter_phage	9.8e-138	62.3
WP_077999975.1\|1194209_1194545_-	DUF2590 family protein	F1BUK8	Cronobacter_phage	1.6e-29	58.7
WP_097364153.1\|1194541_1196677_-\|tail	phage tail tape measure protein	Q94MY4	Haemophilus_virus	2.6e-64	28.4
WP_077999977.1\|1196871_1197141_-\|tail	putative phage tail assembly chaperone	A5X9I7	Aeromonas_virus	1.3e-13	54.2
WP_097364155.1\|1197249_1197645_-	hypothetical protein	F1BUL2	Cronobacter_phage	2.0e-10	38.2
WP_097364156.1\|1197644_1197986_-	M15 family metallopeptidase	F1BUL3	Cronobacter_phage	1.0e-39	77.2
WP_015460863.1\|1197982_1198273_-\|holin	holin	C7BGD7	Burkholderia_phage	3.0e-16	47.9
WP_097364157.1\|1198285_1198741_-	DUF2597 family protein	A5X9I1	Aeromonas_virus	5.6e-49	62.9
WP_097364158.1\|1198740_1199892_-	DUF2586 family protein	F1BUL5	Cronobacter_phage	7.8e-124	60.5
WP_097364159.1\|1199892_1200633_-	phage virion morphogenesis protein	F1BUL6	Cronobacter_phage	4.2e-30	36.6
WP_157757869.1\|1200616_1201117_-\|tail	phage tail protein	F1BUL7	Cronobacter_phage	1.1e-29	42.9
WP_077999984.1\|1201137_1201629_-\|head	head completion/stabilization protein	F1BUL8	Cronobacter_phage	5.5e-42	57.8
WP_097364161.1\|1201686_1202385_-\|terminase	terminase	F1BUM0	Cronobacter_phage	5.5e-64	56.2
WP_097364162.1\|1202389_1203439_-\|capsid	phage major capsid protein, P2 family	Q94MZ4	Haemophilus_virus	7.7e-86	47.8
WP_097364163.1\|1203447_1204347_-\|capsid	GPO family capsid scaffolding protein	R9TRS3	Vibrio_phage	1.5e-34	37.2
WP_097364700.1\|1204536_1206309_+\|terminase	terminase	F1BUM5	Cronobacter_phage	2.9e-202	58.6
WP_097364164.1\|1206308_1207358_+\|portal	phage portal protein	Q94MZ7	Haemophilus_virus	8.5e-101	55.9
WP_097364165.1\|1207354_1207678_+	ogr/Delta-like zinc finger family protein	F1BUM8	Cronobacter_phage	5.9e-37	75.2
WP_097364166.1\|1207689_1207860_-	hypothetical protein	NA	NA	NA	NA
WP_097364167.1\|1207975_1210027_-	replication endonuclease	F1BUM9	Cronobacter_phage	3.7e-241	62.6
WP_097364168.1\|1210023_1210314_-	DUF5405 family protein	NA	NA	NA	NA
WP_097364169.1\|1210306_1211119_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	F1BUN1	Cronobacter_phage	1.7e-88	60.5
WP_097364170.1\|1211109_1212006_-	DNA cytosine methyltransferase	W0LM09	Edwardsiella_phage	4.1e-120	66.3
WP_097364171.1\|1211996_1212227_-	DUF2732 family protein	NA	NA	NA	NA
WP_097364172.1\|1212304_1212700_-	hypothetical protein	NA	NA	NA	NA
WP_077999995.1\|1212717_1213071_-	hypothetical protein	NA	NA	NA	NA
WP_077999997.1\|1213272_1213779_-	phage regulatory CII family protein	F1BUN6	Cronobacter_phage	5.4e-45	61.0
WP_097364174.1\|1214172_1214748_+	phage repressor protein CI	A0A218M4J1	Erwinia_phage	5.1e-31	39.2
WP_097364175.1\|1214766_1215522_+	hypothetical protein	NA	NA	NA	NA
WP_097364176.1\|1215523_1216585_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.8e-114	57.2
WP_097364177.1\|1216900_1217563_-	fructose-6-phosphate aldolase	M4SLG0	Cyanophage	2.9e-22	29.0
1216659:1216709	attR	NA	NA	NA	NA
WP_035594207.1\|1217707_1218607_+	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_097364178.1\|1218611_1221044_+	formate C-acetyltransferase/glycerol dehydratase family glycyl radical enzyme	A0A2K8HAT8	Bacteriophage	1.8e-08	47.4
WP_005281507.1\|1221101_1221500_-	YgiW/YdeI family stress tolerance OB fold protein	NA	NA	NA	NA
WP_005295876.1\|1221713_1222373_+	two-component system response regulator QseB	NA	NA	NA	NA
WP_097364179.1\|1222372_1223737_+	two-component system sensor histidine kinase QseC	NA	NA	NA	NA
WP_005281498.1\|1223747_1224908_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A142C026	Faustovirus	1.3e-14	26.0
WP_097364180.1\|1225069_1226227_-	23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG	NA	NA	NA	NA
WP_005295882.1\|1226303_1226807_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_097364181.1\|1226862_1227843_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_035597119.1\|1227856_1228774_-	DMT family transporter	NA	NA	NA	NA
WP_005281478.1\|1229179_1230148_+	TerC family protein	I7HPH5	Enterobacteria_phage	8.8e-36	34.8
WP_005281471.1\|1230496_1231738_+	serine/threonine transporter SstT	NA	NA	NA	NA
WP_005281469.1\|1231785_1232310_-	YgjV family protein	NA	NA	NA	NA
WP_097364701.1\|1232371_1233862_-	altronate dehydratase	NA	NA	NA	NA
WP_097364182.1\|1233880_1235359_-	tagaturonate reductase	NA	NA	NA	NA
WP_005281461.1\|1235458_1236868_-	glucuronate isomerase	NA	NA	NA	NA
WP_035597115.1\|1237386_1238682_+	MFS transporter	NA	NA	NA	NA
WP_005281457.1\|1238863_1239631_+	transcriptional regulator ExuR	NA	NA	NA	NA
WP_005281452.1\|1239910_1240300_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.5e-07	34.8
WP_005281448.1\|1240491_1240956_+	hypothetical protein	NA	NA	NA	NA
WP_005281444.1\|1241057_1241738_+	DedA family protein	NA	NA	NA	NA
WP_035594201.1\|1241790_1242153_+	EnvZ/OmpR regulon moderator MzrA	NA	NA	NA	NA
WP_005281437.1\|1242427_1242733_+	DUF883 domain-containing protein	NA	NA	NA	NA
WP_005281434.1\|1242732_1243137_+\|holin	phage holin family protein	NA	NA	NA	NA

DBSCAN-SWA_5

3383884 : 3444333

Escherichia_phage(22.86%)

capsid,integrase,tail,holin,portal

attL 3381144:3381158|attR 3409334:3409348

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3381144:3381158	attL	NA	NA	NA	NA
WP_097364598.1\|3383884_3385021_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	2.5e-66	42.9
WP_097364599.1\|3385007_3385253_-	excisionase	NA	NA	NA	NA
WP_035599856.1\|3385328_3385610_-	DNA breaking-rejoining protein	NA	NA	NA	NA
WP_097364729.1\|3385759_3386728_-	Rha family transcriptional regulator	A0A1U9GXD3	Vibrio_phage	3.1e-41	45.0
WP_097364600.1\|3387399_3388317_+	hypothetical protein	NA	NA	NA	NA
WP_097364601.1\|3389674_3390142_-	hypothetical protein	NA	NA	NA	NA
WP_097364602.1\|3390171_3390321_-	potassium transporter 7	NA	NA	NA	NA
WP_097364603.1\|3390389_3390695_-	hypothetical protein	NA	NA	NA	NA
WP_097364604.1\|3391793_3394271_-	DNA breaking-rejoining protein	H6WRX1	Salmonella_phage	2.9e-91	52.9
WP_097364605.1\|3395225_3396068_-	hypothetical protein	NA	NA	NA	NA
WP_097364606.1\|3396345_3396642_-	hypothetical protein	NA	NA	NA	NA
WP_097364730.1\|3397064_3399572_-	S8 family peptidase	NA	NA	NA	NA
WP_097364607.1\|3399588_3400575_-	ATP-binding protein	A0A2K9R7H3	Dishui_lake_phycodnavirus	8.2e-13	30.4
WP_097364608.1\|3400815_3401445_-	helix-turn-helix domain-containing protein	A0A0N7BTS4	Escherichia_phage	1.8e-66	57.9
WP_073382248.1\|3401586_3401796_+	helix-turn-helix transcriptional regulator	A0A0N7C2U7	Escherichia_phage	1.6e-11	50.8
WP_097364609.1\|3401860_3402217_+	hypothetical protein	NA	NA	NA	NA
WP_005286423.1\|3402213_3402447_+	hypothetical protein	NA	NA	NA	NA
WP_005286420.1\|3402478_3402730_+	hypothetical protein	NA	NA	NA	NA
WP_097364611.1\|3402932_3403871_+	helix-turn-helix domain-containing protein	Q76H52	Enterobacteria_phage	1.2e-29	66.3
WP_097364612.1\|3403867_3405250_+	AAA family ATPase	A0A2H4FQW0	Salmonella_phage	2.7e-163	66.0
WP_097364613.1\|3405277_3405625_+	hypothetical protein	NA	NA	NA	NA
WP_097364614.1\|3405734_3406379_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	6.1e-17	31.2
WP_035603599.1\|3406381_3406687_+	DUF1364 domain-containing protein	A0A2K8HR56	Pseudomonas_phage	7.8e-15	46.7
WP_146196788.1\|3406748_3407078_+	hypothetical protein	NA	NA	NA	NA
WP_157757877.1\|3407101_3407374_+	hypothetical protein	NA	NA	NA	NA
WP_097364615.1\|3407486_3407999_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_005286394.1\|3408093_3408402_-	helix-turn-helix transcriptional regulator	A0A088CD40	Shigella_phage	2.0e-42	89.2
WP_015871332.1\|3408391_3408721_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	1.3e-39	88.5
WP_097364616.1\|3409165_3409936_+	Rha family transcriptional regulator	A0A0P0ZGC2	Escherichia_phage	5.6e-25	55.5
3409334:3409348	attR	NA	NA	NA	NA
WP_157757878.1\|3410117_3411413_+	hypothetical protein	NA	NA	NA	NA
WP_097364618.1\|3411534_3412353_+	hypothetical protein	NA	NA	NA	NA
WP_157757879.1\|3412586_3412985_+	hypothetical protein	NA	NA	NA	NA
WP_015871327.1\|3413101_3413332_+	ParD-like family protein	NA	NA	NA	NA
WP_035603613.1\|3413306_3413636_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_097364619.1\|3413726_3414065_+\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	2.1e-24	48.6
WP_097364620.1\|3414067_3414619_+	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	8.8e-73	71.9
WP_097364621.1\|3414709_3415582_+	antA/AntB antirepressor family protein	A0A0R6PJV6	Moraxella_phage	1.5e-21	48.7
WP_097364622.1\|3415756_3416299_+	DUF2514 family protein	A0A193GYI0	Enterobacter_phage	2.0e-08	32.6
WP_005286367.1\|3416379_3417156_+	hypothetical protein	A0A077KBY7	Edwardsiella_phage	5.8e-06	57.8
WP_005294233.1\|3417133_3418810_+	hypothetical protein	B0FEF1	Escherichia_phage	1.1e-232	70.8
WP_097364623.1\|3418806_3420921_+\|portal	portal protein	A0A0P0ZG74	Escherichia_phage	2.5e-229	63.6
WP_097364624.1\|3420992_3421274_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	2.4e-18	49.5
WP_005286352.1\|3421263_3421515_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_097364625.1\|3421793_3422792_+	hypothetical protein	A0A1I9KFD1	Aeromonas_phage	1.7e-34	39.1
WP_097364626.1\|3422809_3424054_+\|capsid	N4-gp56 family major capsid protein	A0A088CC32	Shigella_phage	8.1e-167	72.0
WP_097364627.1\|3424109_3424514_+	hypothetical protein	NA	NA	NA	NA
WP_097364628.1\|3424555_3425026_+	hypothetical protein	A0A2L1IV43	Escherichia_phage	6.0e-22	53.4
WP_097364629.1\|3425012_3425594_+	hypothetical protein	A0A1I9KFD5	Aeromonas_phage	1.4e-20	37.9
WP_077999886.1\|3425593_3426256_+	hypothetical protein	Q08J85	Stx2-converting_phage	2.0e-63	55.3
WP_097364630.1\|3426252_3429210_+\|tail	tail fiber protein	K7P7Q7	Enterobacteria_phage	3.8e-29	47.1
WP_097364631.1\|3429211_3429829_+\|tail	tail fiber assembly protein	A0A218M4J2	Erwinia_phage	4.8e-27	38.1
WP_157757880.1\|3429951_3430125_+	hypothetical protein	NA	NA	NA	NA
WP_097364632.1\|3430139_3431744_+	hypothetical protein	A0A088CBK0	Shigella_phage	6.1e-167	55.3
WP_097364633.1\|3431740_3433297_+	DUF1983 domain-containing protein	A0A2L1IV54	Escherichia_phage	1.0e-81	45.8
WP_097364634.1\|3433304_3433676_+	hypothetical protein	A0A088CC37	Shigella_phage	7.8e-17	40.9
WP_097364635.1\|3433686_3434262_+	hypothetical protein	A0A1I9KFE8	Aeromonas_phage	2.3e-44	52.2
WP_097364636.1\|3434298_3434679_+	hypothetical protein	A0A1I9KFD7	Aeromonas_phage	8.0e-25	49.2
WP_005286316.1\|3434680_3434941_+	hypothetical protein	NA	NA	NA	NA
WP_097364637.1\|3434953_3436405_+	cytokinesis protein SepA	A0A1I9KFD9	Aeromonas_phage	5.8e-15	22.0
WP_097364638.1\|3436503_3444333_+	hypothetical protein	A0A1I9KFG8	Aeromonas_phage	1.4e-232	48.3

DBSCAN-SWA_6

3616717 : 3626039

Brazilian_cedratvirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077999467.1\|3616717_3617485_-	vitamin B12 ABC transporter ATP-binding protein BtuD	A0A2R8FG22	Brazilian_cedratvirus	8.9e-07	28.2
WP_097364732.1\|3617477_3618503_-	vitamin B12 ABC transporter permease BtuC	NA	NA	NA	NA
WP_005285820.1\|3618489_3618693_-	protein DsrB	NA	NA	NA	NA
WP_005285818.1\|3618782_3619079_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	2.4e-13	41.1
WP_077999470.1\|3619083_3621471_-\|tRNA	phenylalanine--tRNA ligase subunit beta	A0A1L3IZU3	BeAn_58058_virus	2.4e-05	23.7
WP_005293646.1\|3621485_3622469_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	6.4e-34	42.6
WP_106120997.1\|3622657_3622702_-	pheST operon leader peptide PheM	NA	NA	NA	NA
WP_005285808.1\|3622870_3623227_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_005293643.1\|3623270_3623468_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_071523971.1\|3623564_3624107_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.3e-16	34.8
WP_005293637.1\|3624110_3626039_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.1e-127	37.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage