CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	1 crisprs	NA	0	3	1	0
NZ_CP017690	Geobacillus thermodenitrificans strain ID-1 chromosome, complete genome	5 crisprs	DinG,cas3,DEDDh,csa3,WYL,cas9,cas1,cas2,cas6,cas14j,c2c9_V-U4,csm6,csx1,cmr1gr7	0	8	14	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017691_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017691_1

61079-61307

Orphan

Consensus_repeat	Method
GTTTTTATCTTACCTATGAGGAATTGAAAC	PILER-CR
GTTTTTATCTTACCTATGAGGAATTGAAAC	CRT

3 spacers

The CRISPR arrays of NZ_CP017691_1

>merge|NZ_CP017691|1|61079-61307|PILER-CR,CRT
GTTTTTATCTTACCTATGAGGAATTGAAACATGCTTTCAGCAACCCAATGGCTGTTTGTGCCGTAGCGTTTTTATCTTACCTATGAGGAATTGAAACTCAGTTGCTTCGTCTACAATTCCTCCTGTTTCTGTGTTTTTATCTTACCTATGAGGAATTGAAACCATTCAGGACAATCTAATTCAAAAGCGATGCGGTCAAGTTTTTATCTTACCTATGAGAAGCAGCTTA

>NZ_CP017691|1|1|61079-61240|PILER-CR
GTTTTTATCTTACCTATGAGGAATTGAAAC	ATGCTTTCAGCAACCCAATGGCTGTTTGTGCCGTAGC
GTTTTTATCTTACCTATGAGGAATTGAAAC	TCAGTTGCTTCGTCTACAATTCCTCCTGTTTCTGT
GTTTTTATCTTACCTATGAGGAATTGAAAC

>NZ_CP017691|1|1|61079-61307|CRT
GTTTTTATCTTACCTATGAGGAATTGAAAC	ATGCTTTCAGCAACCCAATGGCTGTTTGTGCCGTAGC
GTTTTTATCTTACCTATGAGGAATTGAAAC	TCAGTTGCTTCGTCTACAATTCCTCCTGTTTCTGT
GTTTTTATCTTACCTATGAGGAATTGAAAC	CATTCAGGACAATCTAATTCAAAAGCGATGCGGTCAA
GTTTTTATCTTACCTATGAGAAGCAGCTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017691.1\|WP_099233685.1\|59110_60025_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NZ_CP017691.1\|WP_087960303.1\|62504_63638_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP017691.1\|WP_099233673.1\|46922_47651_+\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|307807
NZ_CP017691.1\|WP_099233681.1\|54985_55483_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP017691.1\|WP_049752141.1\|61713_62121_+\|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	unknown
NZ_CP017691.1\|WP_015863856.1\|56087_56813_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017691.1\|WP_099233677.1\|50602_51907_-\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341198
NZ_CP017691.1\|WP_099233679.1\|51893_53393_-\|SAM-dependent-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|223363
NZ_CP017691.1\|WP_004888727.1\|66551_67253_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP017691.1\|WP_099233687.1\|62139_62466_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NZ_CP017691.1\|WP_099233691.1\|68008_69247_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP017691.1\|WP_042386261.1\|65741_65963_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370129
NZ_CP017691.1\|WP_099233689.1\|63607_65506_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NZ_CP017691.1\|WP_099233683.1\|57451_58684_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP017691.1\|WP_081188680.1\|55500_55998_+\|GrpB-family-protein	unknown	unknown	gnl\|CDD\|377252
NZ_CP017691.1\|WP_099233671.1\|46279_46858_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NZ_CP017691.1\|WP_081105553.1\|70699_71734_-\|YcaO-like-family-protein	unknown	unknown	gnl\|CDD\|274674
NZ_CP017691.1\|WP_099233693.1\|69630_70686_-\|YcaO-like-family-protein	unknown	unknown	gnl\|CDD\|274674
NZ_CP017691.1\|WP_042386258.1\|67265_67997_-\|ABC-transporter-permease	unknown	unknown	unknown
NZ_CP017691.1\|WP_099233675.1\|47675_50606_-\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683

Protein	Function_ID	Function_description	E-value
NZ_CP017691.1\|WP_099233685.1\|59110_60025_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	3.63685e-54
NZ_CP017691.1\|WP_004888727.1\|66551_67253_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.51236e-41
NZ_CP017691.1\|WP_099233673.1\|46922_47651_+\|M48-family-metallopeptidase	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	1.62949e-63
NZ_CP017691.1\|WP_099233681.1\|54985_55483_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.38156e-20
NZ_CP017691.1\|WP_099233679.1\|51893_53393_-\|SAM-dependent-DNA-methyltransferase	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	4.69747e-151
NZ_CP017691.1\|WP_099233677.1\|50602_51907_-\|restriction-endonuclease-subunit-S	gnl\|CDD\|341198	cd17517, RMtype1_S_EcoKI_StySPI-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR),similar to Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) TRD2-CR2, Salmonella enterica subsp. enterica serovar Potsdam S subunit (S.StySPI) TRD2-CR2, and other TRD-CR's. Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) recognizes 5'... AACNNNNNNGTGC ... 3' and Salmonella enterica subsp. enterica serovar Potsdam S subunit (S.StySPI) recognizes 5'... AACNNNNNNGTRC ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.EcoKI-TRD1 and S.StySPI-TRD1 both recognize AAC/GTT, S.EcoKI-TRD2 recognizes GCAC/GTGC and S.StySPI-TRD2 recognizes GYAC/GTRC. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2.It also includes TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases, such as Pseudomonas putida Jo 4-731 Type IIG restriction enzyme/N6-adenine DNA methyltransferase (RM.PpiI), and type I DNA methyltransferases such as Bacillus cereus BDRD-ST24 M subunit of Type I N6-adenine DNA methyltransferase (M.Bce24ORF51270P). RM.PpiI recognizes 5' ... GAACNNNNNCTC ... 3'.	7.53509e-60
NZ_CP017691.1\|WP_087960303.1\|62504_63638_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.47553e-25
NZ_CP017691.1\|WP_099233687.1\|62139_62466_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	8.99114e-13
NZ_CP017691.1\|WP_099233691.1\|68008_69247_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	3.80582e-65
NZ_CP017691.1\|WP_042386261.1\|65741_65963_+\|hypothetical-protein	gnl\|CDD\|370129	pfam08797, HIRAN, HIRAN domain. The HIRAN domain (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. The HIRAN domain is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this domain functions as a DNA-binding domain that probably recognizes features associated with damaged DNA or stalled replication forks.	5.8592e-07
NZ_CP017691.1\|WP_099233689.1\|63607_65506_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	5.07083e-129
NZ_CP017691.1\|WP_099233683.1\|57451_58684_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.76292e-40
NZ_CP017691.1\|WP_081188680.1\|55500_55998_+\|GrpB-family-protein	gnl\|CDD\|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	2.54692e-16
NZ_CP017691.1\|WP_099233671.1\|46279_46858_-\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	9.48104e-17
NZ_CP017691.1\|WP_081105553.1\|70699_71734_-\|YcaO-like-family-protein	gnl\|CDD\|274674	TIGR03604, hypothetical_protein, thiazole/oxazole-forming peptide maturase, SagD family component. Members of this protein family include enzymes related to SagD, previously referred to as a scaffold or docking protein involved in the biosynthesis of streptolysin S in Streptococcus pyogenes from the protoxin polypeptide (product of the sagA gene). Newer evidence describes an enzymatic activity, an ATP-dependent cyclodehydration reaction, previously ascribed to the SagC component. This protein family serves as a marker for widely distributed prokaryotic systems for making a general class of heterocycle-containing bacteriocins.	1.38135e-09
NZ_CP017691.1\|WP_099233693.1\|69630_70686_-\|YcaO-like-family-protein	gnl\|CDD\|274674	TIGR03604, hypothetical_protein, thiazole/oxazole-forming peptide maturase, SagD family component. Members of this protein family include enzymes related to SagD, previously referred to as a scaffold or docking protein involved in the biosynthesis of streptolysin S in Streptococcus pyogenes from the protoxin polypeptide (product of the sagA gene). Newer evidence describes an enzymatic activity, an ATP-dependent cyclodehydration reaction, previously ascribed to the SagC component. This protein family serves as a marker for widely distributed prokaryotic systems for making a general class of heterocycle-containing bacteriocins.	9.06632e-14
NZ_CP017691.1\|WP_099233675.1\|47675_50606_-\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	4.51086e-178

>NZ_CP017691.1|WP_099233685.1|59110_60025_-|tyrosine-type-recombinase/integrase
MLNEYVTYLQEKGASPNTIISYTNDLNIFFNDLHIRPGDYVTTADIRKWIQQMLNPAEGKPLAISTINRRLNSLRSFYAWAVEHYKLEQNPMKDIQDLKSADEDNEKIMWLTEEEFEDLLHRMRKKPVQSRGVDPEEKYRRDRAVVYLLTYAGLRVEELSNLKLTDLDLEMKRIRIVGKGMKVRTVPISNILLAELEDWLQFRAEMAKKKPHVAESPYVFYSQRSPKFSVRGIQRMIESYSLPNKKLTPHMFRHTFCKWMLKATNNDIEKVRRLAGHSNIATTSRYLKDSYSDLADAVEALPKF
>NZ_CP017691.1|WP_099233683.1|57451_58684_-|serine/threonine-protein-kinase
MITIKNIDNFLLLKLNQVFSNYDSEEVVLYRGFYNDIKHETLRRIFSIIHCRLNKLFSFMNYKNKPGVGGHYNAHESRELIDLINQIRVIQATLKEENSEFYFEIDSYYEEILETCMQFLSEIGGSSIPEDFPKINIIEHKPIFTLVNSTMVESPFNMKSAVRIRLIGEGSYAKVFKYRDPYYNCDFAIKRANEDLRPDELERFRNEYNVLKTLNSPFIIKAYHYNEEKNEYTMELADQTLEKFISRNNGSIPFHTRRDLVIQLLNAFEYIHSKGILHRDISYQNILIKQYDDGSSWVKVTDFGLVKRPESKLTRQGTEIKGVINDYSDLRKVGFENYEIRHETYALAQVIYFILTGRKGEFTREKNTELKKFILKAVSANKEERFTSVKEMREELIRVVLPSLKSEIKC
>NZ_CP017691.1|WP_015863856.1|56087_56813_+|hypothetical-protein
MGRLWLFFVVASIGMALRFLVLGKFEWGQLLIVSGFLAGVLLIWGIERWQAWRDASYEGAEDEDVWHTHMAERFWTGKKRLFKGTKKMGEFWRFFPLPWQRIVNSILSDQNQWYLNLSFAFADGTSVQIIEQREKLFRVNDTWHIVQNGAVVAVARTDYSWKNKLKLRERMIVEIQGKTLFFQSPEMVSRTEVWLDGKMIAEGKRSRLLRWRYTFRVNEGYEEWERLLVAAYVLFNYAYHQ
>NZ_CP017691.1|WP_081188680.1|55500_55998_+|GrpB-family-protein
MELVHFIEQSHFHEQAEKTFLEQKEKILRLLPEADIQHVGSTAIPNSLTKGDLDIQVRVPAEIFTVAVEKLSALYAINEGSVQTDYFRAFQDDTTDPPLGVQLTVIGSELDIFWKFREVLLANDTYRAEYDELKKAYEGKSMEAYREAKQRFFARLMETPEFQRL
>NZ_CP017691.1|WP_099233681.1|54985_55483_+|GNAT-family-N-acetyltransferase
MNVRHAMVDDAEELAHLILQVEKEAEFMLFEAGERTLTPDLQRSQIEAMQNEENSTILVAEADGKLVGYLVARGGRARRNKHTVYIVIGVLASYRGKGIGTMLFAELERWARTKGIHRLELTVVVNNQRAVSLYRKMGFEREGIKRHSLLIHGQYIDEYYMAKLL
>NZ_CP017691.1|WP_099233679.1|51893_53393_-|SAM-dependent-DNA-methyltransferase
MELTTQKLTLQQLESHLWESANILRGSIDSSDYKNYIFGLLFLKRLNDVFVETAERIEREEGEDYGWYDRDEHQFFVPERARWSYITSLTQDIGAAINKAFEELEEENPSLEGVLASIDFNDKEKLPDKLLMQLLQHFSKIDLRNENLSEPDILGRAYEYLIKQFADDAGKKGGEFYTPSQVVRLIVKLIKPEEGMRICDPTVGSAGMLIQSVDYIKEKGGNPRNLTLHGQEKNLNTWAIAKMNLLLHGLSDHRIEKGDTIREPKLLDENGELLLYDRVIANPPFSLKNWGREEAEADPYGRFRFGLPPKNAGDLAFVQHMIATLNHRGIAGVVMPHGVLFRGGAEGKIRQGILEEDLLEAVIGLPANLFYGTGIPACILILNRNKTPERKGHVLFIDASRDYQEGKNQNVLRDQDIDKIVSAFEKWEDQDKYCRVVSLEEIKENDYNLNIARYVDTTEEEEQIDITEALRQLRQLEKEREEIEKVMYGYLKELGYGEL
>NZ_CP017691.1|WP_099233677.1|50602_51907_-|restriction-endonuclease-subunit-S
MVNYNQQNTWKYGSLKNFGDFKNGVNKGKEDFGHGTKFVNIQDIFRHPIIDSTQLNRVNVSDKEVATYRLEKGDILFVRSSVKPEGVGYPALFMGADEDVVYSGFTIRYRPVNGIFDSKFLLYTLLSDNFRRKLLSLATISANTNINQEALSSLEVPVPPIAEQHKIAAILSSVDEAIEKTEAIIEQTEKVKKGLMQQLLTKGIGHTKFKKTEIGEIPEEWEVKELKDLANPYDKYSFTGGPFGSDLTSEDYTEEGVQIIQLQNIKEGYFSNDYKIFTSEEKANQLSSCNIYPGDIIIAKMADPVARACIVPNHSKRFLMASDGIRLSVDKRKYVTEYVTYAINAPYFRKQAINNSTGTTRLRIGLSALRKLKILIPSYEEQQKIADIMTTIDQKIEFEKMKIKKLTDIKKSLMQSLLTGKVRVKVDEDEVTSS
>NZ_CP017691.1|WP_099233675.1|47675_50606_-|type-I-restriction-endonuclease-subunit-R
MSYEWAKERPVEHRLIKQFEGLGYTYLPGSALDSERASHRDVVLEKRLRQAIQRLNPWIDDINLHKVVRMVTHINAASVIEANEKFYDMVVNYVSIQQDLGKGKKSQTVKLIDFDHPENNEFLVVNQFKVSGPMTTIIPDVVLFVNGLPLVVIECKSPTKPHPISEAVQQLLRYQQEAERLFHYNHVVVATCNEQAKFGSIGARLRHFGEWKDPYPLKPSDIGANPTRQDILVAGMFPKKNLLDMIQNFVVYEAEGGRTIKKVCRYQQFRAANKAVERILTGKTPKERGGVVWATQGSGKSLTMLYLSVKLRRLKELRNPSIVIVTDRTDLDEQITNTFRRCGFPNPQRAESVKDLRELLRTAIGATIMTTIQKFQDHADDGEDLFLNDADNIFVLVDESHRTNYGGLAMNMRASLPNAVYIGFTGTPIDKEDRSTVQTFGTYIDTYTIQQAVEDGATVPIYYESRLPELRVEGESLDAIFERVFQDYSKEEREQIKKKYATEEAIIGAPQRIRRICLDIIEHYEKHIAPNGFKAQIVAINRETAVLYKEILDELNGPESVVIISPNNNDDERLKKYHLTKEQQKHYIERFKKPLHEDKLAFIIVCDMLLTGFDAPIEQVMYLDKPLKEHNLLQAIARTNRTYDKKTYGLIVDYYGVSAFLKQALAIFNPTDIQGALTSIQSEIPRLQSRHRAAMRFFDGVNRDDIEACMKILEPEDVRHAFDRAFKRFSESMDMIMPHPEAKPYYEDLKFLGKVRQYARNRFRDEQMDISDCGEKVKQLIYDHIYTTDIKALHRPVSILEKNFDAHVKSLTTDEAKASEMEHAIRHEIKVKIDQNPVYYTSLKERLEQLIKARKEKRLNDAQLAFELEKLIEEMRGQSKTIEEEGLTPQSYPIFQLLQKEWTDQEEEKERLKEITQIIVEHIEGLVVIDWVNKEDVKREMRKKIKRQLRTSKCPSDKIEALAQQIVELAEIHYKK
>NZ_CP017691.1|WP_099233673.1|46922_47651_+|M48-family-metallopeptidase
MPTFQFGTTAIEYTLQQVKGKEDISIVVEWMEGVTVVAPDHLVLEEINRVLRKKATWILDKWNSLNKIKRPPAPLEFVSGEKLPYLGRYYRIKVKQNQDIDKVKVLFHQGKFYIETPTSADDIEHVPMIREALKSWYIQRAQVKAEERVKRYAQRLGVTPAKLAVKEQKFRWGTCTPQGAIYLNWRLFLAPMRVVDYVIVHELAHLRYADHSKNFWNLVRSILPDYEERKEWLRVNGPTLTI
>NZ_CP017691.1|WP_099233671.1|46279_46858_-|site-specific-integrase
MDLSPKIPLHKYRCVHVIIYLRTYACLCVEEISNLKITDLNLELKRIRIVDKIMKVVPISEDFISRTRGLVEVSSGNGQKKKLYVAASPYVFYSQRSLKFLLRGMQRMIESYILPNKKLTLHMFRHTFCKWMLKATNNDIEKVRRLAGHSNIATTSRYSSFVKSTISFLRSLVSSLFIRFFLHSNILFKTMF
>NZ_CP017691.1|WP_049752141.1|61713_62121_+|ribbon-helix-helix-protein,-CopG-family
MMEGRCYERHDFQVLVLQEFGKRRPRSPEETKRLQEEYLRLLEEIPRMWEEFVEKHKNIYERFGYLDVVVHDDLRVERKKLQRGRPKEEKSKSYRITVRLDDELYELLQKYCQTKNMSESEAVRQLISELKWKRF
>NZ_CP017691.1|WP_099233687.1|62139_62466_-|ATP-dependent-helicase
MLQERCSFFYTLWILLDNQHACCVYLIGASDYILPHAVAIQGAEDMITTQQKHNKSKNTSVNEAIEEERRLMYVAVTRAKEELYISSPKTFRNRDLEISRFLIDSFNQ
>NZ_CP017691.1|WP_087960303.1|62504_63638_+|IS4-family-transposase
MNKHTTLPNLMQKLVSDEEIQLIAEAVGYRDSSRTFTLRELIHFFLLAAMHQWKSFRHGADVGPLYGLPRFHYSTVSKKAKEVPYDIMKRLLALIISKCNRQTRRSLRFPKPLRVVDSTTVTVGKNRLPWAPYHGERAGVKLHVAYSPESSLPADVVETIGLRHDGPVGEQLTNAQQVLVEDRAYFKIERLDRFVEQHQLFVIRMKDNIELHQKKSLKRLSSTSSSVQADFTCQLGTKQCRSTKRHRVVIFRDANGRDIRVVTNLFHASAETIADMYQQRWTVEVFFRWVKQYLNVPTLFGTTENAVYNQLFAAFIAYVLLRWLYDQTKKQTNVSLSFISFVRRFFSGQLPLDWKSGMAAALFDYAQIYGRRMYNFG
>NZ_CP017691.1|WP_099233689.1|63607_65506_-|ATP-dependent-helicase
MKLFNPFYKKPINFHKKPINSRKEIPIAEVLNPLTTKQLVKENDHDQFYFRMLEQQGIVLNERQLEAVRQTEGPVLTLAGAGSGKTSVLTARVGYLINVKKVKPENILVLTFTRKAAEEIKERIAQLPGLSKNTVRNLVAGTFHSVFLQILKSQGYDYKILSNEKHKEVIIKRILKDMGLKDDYDPETILSLISYSKNQLLTIEDLPEQTPVEREFKDIFRRYEEWKNKEHYMDFDDMLVYTYDLLNENQRLLERLQERFKYIEVDEFQDTNIAQYRVLQMLAEKHKNLFVVGDDDQSIYAFRGASSDIILNFPKDYPNTHIVKLDVNYRSNPSIVGLGNEIIKYNQKRHVKTLRCYKRSNEYLTPFYMRPKDTADEAQLIVENMRSDVRQGTRKWKDFVVLYRTHAVSRAIVEQLVLKNIPFVVYGDKKPFYEHPIVKPVLDYIRLSINPNDLNALKSILPTMYLNRDKAIDYITTEMVFNPLDESETLLHYLLRMPGLHPSQKELIIERIRLLDDIKKMSPVDAIREIRQGKGQYEKYLEIDQRRSFTLQKEFANEMLDELVASAIPHKTHESYLNLIDKILKKHEEMEELKNDPYADVVSLMTIHNAKGLEFPCVYTSVDYPKLYIRLP
>NZ_CP017691.1|WP_042386261.1|65741_65963_+|hypothetical-protein
MRFYARLKVAGVTFENRQSIIKNMDILDPIFLKRERSNPHDSNAIAVYHVNGCFLQAKSAENCKKKYIGLPAQ
>NZ_CP017691.1|WP_004888727.1|66551_67253_-|ABC-transporter-ATP-binding-protein
MHVFNLKYKYKKAKDYVLNGVTFTLNTKKLNVIVGLNGAGKTTLFDCLTGNLTPETGEISLPDKKEMLYLTQNIFFSPEIKGKDFAKFVARLSGKKGSNQIDDYLDFLDSRERELMAHLWSMKIGKMSVGERKWLFITLLSSIERKLYIFDEPTSGVDPSSRLKIMNKFKKLIENQRICIISTHQLQDLSYIDSHLIFLHKGKVLYEGDFQDWLKLFNTINPDEAFARMIEQG
>NZ_CP017691.1|WP_042386258.1|67265_67997_-|ABC-transporter-permease
MRQVLAFYLLYLKMLLAEKIALIWSVIFPVVIALVFQRGFLNDATDEKEIVQYISFFWVFIIISIYINGIGLQIARIREYGLLKTYVMITGNRYTFLTAILLTQISFGAISLLLFTSIVSIYYRAFSFNLLLSSLIVLLVSFPLAIASVSIAAIPIKFNNLSTIMNILVYPLFFLSLNSRSSNLLNYVNPYYIIHEITEIVINLLMGIDYTYNFYLLLLSILLYLVVGLFIIKRFNLLSLTSR
>NZ_CP017691.1|WP_099233691.1|68008_69247_-|insulinase-family-protein
MRVLSINNNRIILNKKPNYKTVSVGVFLNMGSKFEQEEESGISHFIEHMLLTSNLKYHKTSTRQIVEDLGGFINAFTTKEFTCIHGKVISEYSEILVEILIDIIKYPAFKQEDIEREKNVILNEIQSFNNNGMHVCQQKLLKNLFKGHPLSNEILGNRDSIRKFNREQLIEYYLETLNREIVICITGDFDEERIIDIINKKDIFNSKKNITPRQFNKVIYSNFNIIKYHSNLGNYISFALPGYSYHEIDTVYLSFLTCILGYGSTSLLNRILRDEMGLIYNLNAYLHTYNEGGALIISTTSNSASNIDRIISIFGEVIERLKNRGLDKKDFDRVHSIIKSQILFKTENPHDIMLELGRNELLGINNNRSIVDYNNLNKTMENLKEITYEYFCDFLKKFFEQPFSYYGLLNEK
>NZ_CP017691.1|WP_099233693.1|69630_70686_-|YcaO-like-family-protein
MIRDRSKAPYIRDSIKIDRSMFLNQGKQSYISSKFYKTVNGHNANFNLSSVIKSSIGEFIERHSLLTHPYKIGDMIPSFHLTSGKIINVPAEQIVFIKNSVFNDSCGVASHLNSKNAVEKAFFEFFERQSLIFNWLTKSRGKRIDLKKFNSEKISKLQWLLLKYVDEIHLFEISLHPLIKVVFGIGIGEFYKTLGISAKLNVTEAVESTMEEMYQTFGSAWSKSYVTRIDDNLQFDHFDMYLQNYYSLSPTILRDEYSYLIDESVEYDENTSSDLTLKEIINLVEYDLGIEIYGCFIPTFHNGFYTKIVKVFSPEGYPHMYPVEFNHAQTKISFNKTVKDFPNAFRPIPFP
>NZ_CP017691.1|WP_081105553.1|70699_71734_-|YcaO-like-family-protein
MIHVLSHHNSFNIPETIFNTEFKLSFNYIGNFLVNNYIGPSGCNAIDKTCRNSFKKGYSEAIERRALMIGGYTNQKEYVDAYNLITKNIESIPVEYSRFKNTSPFYSDTTGTAAHPKSEYAVYKAVVELLEKNSLFLFWYGLVGKRLDVSCMNSELVRSLQHQGKIVDFYLNDTFYPLNTVITIIHNGKDFIYSGGVAGSFNIYKAVLSSLEEAYLLMWQNYFHEKISSNNYFSRPFDSKDYYTALRHIENVQGEEKVSTRKDFSNKPSINRLIEELPCWIKSLHIIMLRHTLNIPLKICLAFSKDLNNHIPLKKRIDLDTTINKCTINLDINKLEKLPECVIV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017691_1	1.1\|61109\|37\|NZ_CP017691\|PILER-CR,CRT	61109-61145	37	NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	61109-61145	0	1.0
NZ_CP017691_1	1.2\|61176\|35\|NZ_CP017691\|PILER-CR,CRT	61176-61210	35	NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	61176-61210	0	1.0
NZ_CP017691_1	1.3\|61241\|37\|NZ_CP017691\|CRT	61241-61277	37	NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	61241-61277	0	1.0
NZ_CP017691_1	1.3\|61241\|37\|NZ_CP017691\|CRT	61241-61277	37	CP017693	Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence	15831-15867	0	1.0
NZ_CP017691_1	1.3\|61241\|37\|NZ_CP017691\|CRT	61241-61277	37	CP017693	Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence	49693-49729	0	1.0
NZ_CP017691_1	1.2\|61176\|35\|NZ_CP017691\|PILER-CR,CRT	61176-61210	35	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	1136640-1136674	8	0.771

1. spacer 1.1|61109|37|NZ_CP017691|PILER-CR,CRT matches to NZ_CP017691 (Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence) position: , mismatch: 0, identity: 1.0

atgctttcagcaacccaatggctgtttgtgccgtagc	CRISPR spacer
atgctttcagcaacccaatggctgtttgtgccgtagc	Protospacer
*************************************

2. spacer 1.2|61176|35|NZ_CP017691|PILER-CR,CRT matches to NZ_CP017691 (Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence) position: , mismatch: 0, identity: 1.0

tcagttgcttcgtctacaattcctcctgtttctgt	CRISPR spacer
tcagttgcttcgtctacaattcctcctgtttctgt	Protospacer
***********************************

3. spacer 1.3|61241|37|NZ_CP017691|CRT matches to NZ_CP017691 (Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence) position: , mismatch: 0, identity: 1.0

cattcaggacaatctaattcaaaagcgatgcggtcaa	CRISPR spacer
cattcaggacaatctaattcaaaagcgatgcggtcaa	Protospacer
*************************************

4. spacer 1.3|61241|37|NZ_CP017691|CRT matches to CP017693 (Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence) position: , mismatch: 0, identity: 1.0

cattcaggacaatctaattcaaaagcgatgcggtcaa	CRISPR spacer
cattcaggacaatctaattcaaaagcgatgcggtcaa	Protospacer
*************************************

5. spacer 1.3|61241|37|NZ_CP017691|CRT matches to CP017693 (Geobacillus lituanicus strain N-3 plasmid pLDW-3, complete sequence) position: , mismatch: 0, identity: 1.0

cattcaggacaatctaattcaaaagcgatgcggtcaa	CRISPR spacer
cattcaggacaatctaattcaaaagcgatgcggtcaa	Protospacer
*************************************

6. spacer 1.2|61176|35|NZ_CP017691|PILER-CR,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 8, identity: 0.771

tcagttgcttcgtctacaattcctcctgtttctgt	CRISPR spacer
tcgcctgcttcgtctacaactcttcctgttacctt	Protospacer
**. .**************.**.******* *. *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

6045 : 63638

Bacillus_phage(23.53%)

integrase,transposase

attL 52337:52351|attR 63907:63921

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611651.1\|6045_7091_-\|transposase	IS630-like element ISBs2 family transposase	NA	NA	NA	NA
WP_078172677.1\|7440_8508_-	thermonuclease family protein	A0A1L2JY19	Aeribacillus_phage	3.5e-86	85.3
WP_060476351.1\|8585_9656_-	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_060476350.1\|9740_10889_-	replication initiation protein	A0A218MNI2	uncultured_virus	6.6e-14	29.3
WP_060475948.1\|12635_13127_+	hypothetical protein	NA	NA	NA	NA
WP_099233653.1\|13550_13991_+	DNA repair protein RadC	NA	NA	NA	NA
WP_012301104.1\|14182_14674_+	hypothetical protein	NA	NA	NA	NA
WP_060475949.1\|14968_15400_-	hypothetical protein	NA	NA	NA	NA
WP_099233655.1\|15525_16113_+	hypothetical protein	NA	NA	NA	NA
WP_099233657.1\|16134_17646_-	hypothetical protein	NA	NA	NA	NA
WP_042409984.1\|17663_18335_-	hypothetical protein	NA	NA	NA	NA
WP_042409983.1\|18340_19384_-	conjugal transfer protein TraL	NA	NA	NA	NA
WP_012301109.1\|19376_19643_-	hypothetical protein	NA	NA	NA	NA
WP_060475952.1\|19663_20212_-	hypothetical protein	NA	NA	NA	NA
WP_060475953.1\|20208_21243_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1X9SGZ2	Bradyrhizobium_phage	9.8e-17	38.6
WP_011888476.1\|21239_23093_-	DUF87 domain-containing protein	NA	NA	NA	NA
WP_060475954.1\|23109_24156_-	hypothetical protein	NA	NA	NA	NA
WP_008881746.1\|24168_24393_-	hypothetical protein	NA	NA	NA	NA
WP_011888478.1\|24513_25149_-	hypothetical protein	NA	NA	NA	NA
WP_099233705.1\|25549_26152_+	DUF3967 domain-containing protein	NA	NA	NA	NA
WP_041265036.1\|26536_27514_+	hypothetical protein	NA	NA	NA	NA
WP_060476368.1\|27558_28086_-\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	2.7e-07	28.5
WP_014195313.1\|28085_28616_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_042409949.1\|29287_29518_-	helix-turn-helix transcriptional regulator	A0A0S2GLH4	Bacillus_phage	3.2e-21	68.1
WP_008881738.1\|29875_30208_+	hypothetical protein	Q0H251	Geobacillus_phage	9.8e-11	38.2
WP_087960395.1\|30221_31379_+	chromosome partitioning protein ParA	Q0H250	Geobacillus_phage	7.6e-119	57.2
WP_099233659.1\|31380_32109_+	replication-relaxation family protein	Q0H249	Geobacillus_phage	1.2e-56	51.5
WP_042385872.1\|32215_32623_+	CopG family transcriptional regulator	NA	NA	NA	NA
WP_042385876.1\|32668_33058_-	hypothetical protein	NA	NA	NA	NA
WP_099233661.1\|33067_34219_-	ParM/StbA family protein	NA	NA	NA	NA
WP_008881732.1\|34668_35214_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	3.0e-57	74.1
WP_099233663.1\|35277_35925_-	hypothetical protein	NA	NA	NA	NA
WP_042385881.1\|35941_36196_-	hypothetical protein	NA	NA	NA	NA
WP_042410068.1\|36170_36422_-	hypothetical protein	NA	NA	NA	NA
WP_099233665.1\|36648_38580_+	MobA/MobL family protein	NA	NA	NA	NA
WP_060476344.1\|38598_40734_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_012301124.1\|40755_42876_+	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	7.2e-91	40.5
WP_041265042.1\|42908_43103_+	hypothetical protein	NA	NA	NA	NA
WP_099233667.1\|43099_44092_+	DUF1738 domain-containing protein	NA	NA	NA	NA
WP_073519239.1\|44099_44465_+	hypothetical protein	NA	NA	NA	NA
WP_042410091.1\|44475_45300_+	hypothetical protein	NA	NA	NA	NA
WP_099233669.1\|45810_46014_-	hypothetical protein	NA	NA	NA	NA
WP_099233671.1\|46279_46858_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_099233673.1\|46922_47651_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_099233675.1\|47675_50606_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.7e-98	29.8
WP_099233677.1\|50602_51907_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.7e-11	25.8
WP_099233679.1\|51893_53393_-	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	6.2e-113	43.6
52337:52351	attL	NA	NA	NA	NA
WP_099233681.1\|54985_55483_+	GNAT family N-acetyltransferase	A0A1B2IAV9	Erwinia_phage	1.4e-05	34.1
WP_081188680.1\|55500_55998_+	GrpB family protein	NA	NA	NA	NA
WP_015863856.1\|56087_56813_+	hypothetical protein	NA	NA	NA	NA
WP_099233683.1\|57451_58684_-	serine/threonine protein kinase	A0A161HRA3	Powai_lake_megavirus	9.6e-11	28.6
WP_099233685.1\|59110_60025_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1P7C7	Bacillus_phage	1.5e-16	27.3
WP_049752141.1\|61713_62121_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_099233687.1\|62139_62466_-	ATP-dependent helicase	U5PSZ2	Bacillus_phage	1.4e-06	42.9
WP_087960303.1\|62504_63638_+\|transposase	IS4 family transposase	NA	NA	NA	NA
63907:63921	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP017690

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017690_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017690_1

42610-43634

Orphan

Consensus_repeat	Method
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRT

15 spacers

The CRISPR arrays of NZ_CP017690_1

>merge|NZ_CP017690|1|42610-43634|PILER-CR,CRISPRCasFinder,CRT
GTTTTTATCGTACCTATGAGGGATTGAAACATGCTCTCTCTAAAATAGCTATTTGCCTGGACATTGAGTTTTTATCGTACCTATGAGGGATTGAAACACAAACACCCCCTTGCACGTTTTGTACACATTTTTCCGCGTTTTTATCGTACCTATGAGGGATTGAAACGCGGGTAAATGTGTACATTTTGTACATGTGGAGGTAGGTTTTTATCGTACCTATGAGGGATTGAAACGGTATGACGATCTCGGCGCTTGGTTCGTATGTGATCGGGTTTTTATCGTACCTATGAGGGATTGAAACCCAATAAAAACTGACATGAAAACTGACATAAAAAGTTTTTATCGTACCTATGAGGGATTGAAACGTAACTATTAGAAATGCTATAGCATCAATAAAACCGTTTTTATCGTACCTATGAGGGATTGAAACTATAGCCGCAGATAAAATGGCAGTTGGGACAGCCACAGGTTTTTATCGTACCTATGAGGGATTGAAACCCATCGGCAATGCATTGGCACCCGCGATTGAAAAAGGTTTTTATCGTACCTATGAGGGATTGAAACAAGGAGCGAGCAGACGCGAGCGACGGAAGGGGGAGCGGTTTTTATCGTACCTATGAGGGATTGAAACATAACATCCGCGTCCACCGCATGGCCAACAGCGAGGTTTTTATCGTACCTATGAGGGATTGAAACCGCTCAACGGTACAGTGTTGACTATCGGTGATTTGTGTTTTTATCGTACCTATGAGGGATTGAAACAAGATTCATCTGCTGTACCAACCAACAAAACAAAAGTTTTTATCGTACCTATGAGGGATTGAAACGATCGCCTGTAATACGATACTGGAACGTTACACCTGCGTTTTTATCGTACCTATGAGGGATTGAAACTCAGCAAATCCTAGCGGCGTTAGATCCAGAAGCGACCGTTTTTATCGTACCTATGAGGGATTGAAACTTTGACGAGCATCCTGAAGTGGCCTGAGGGTTGAATTTTTATCGTACCTATAAGGAGTTCACTT

>NZ_CP017690|1|1|42610-43570|PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGCTCTCTCTAAAATAGCTATTTGCCTGGACATTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAAACACCCCCTTGCACGTTTTGTACACATTTTTCCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCGGGTAAATGTGTACATTTTGTACATGTGGAGGTAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGTATGACGATCTCGGCGCTTGGTTCGTATGTGATCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAATAAAAACTGACATGAAAACTGACATAAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GTAACTATTAGAAATGCTATAGCATCAATAAAACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATAGCCGCAGATAAAATGGCAGTTGGGACAGCCACAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCATCGGCAATGCATTGGCACCCGCGATTGAAAAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGAGCGAGCAGACGCGAGCGACGGAAGGGGGAGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAACATCCGCGTCCACCGCATGGCCAACAGCGAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CGCTCAACGGTACAGTGTTGACTATCGGTGATTTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGATTCATCTGCTGTACCAACCAACAAAACAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GATCGCCTGTAATACGATACTGGAACGTTACACCTGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGCAAATCCTAGCGGCGTTAGATCCAGAAGCGACC
GTTTTTATCGTACCTATGAGGGATTGAAAC

>NZ_CP017690|1|1|42610-43634|CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGCTCTCTCTAAAATAGCTATTTGCCTGGACATTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAAACACCCCCTTGCACGTTTTGTACACATTTTTCCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCGGGTAAATGTGTACATTTTGTACATGTGGAGGTAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGTATGACGATCTCGGCGCTTGGTTCGTATGTGATCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAATAAAAACTGACATGAAAACTGACATAAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GTAACTATTAGAAATGCTATAGCATCAATAAAACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATAGCCGCAGATAAAATGGCAGTTGGGACAGCCACAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCATCGGCAATGCATTGGCACCCGCGATTGAAAAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGAGCGAGCAGACGCGAGCGACGGAAGGGGGAGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAACATCCGCGTCCACCGCATGGCCAACAGCGAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CGCTCAACGGTACAGTGTTGACTATCGGTGATTTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGATTCATCTGCTGTACCAACCAACAAAACAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GATCGCCTGTAATACGATACTGGAACGTTACACCTGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGCAAATCCTAGCGGCGTTAGATCCAGAAGCGACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTGACGAGCATCCTGAAGTGGCCTGAGGGTTGA
ATTTTTATCGTACCTATAAGGAGTTCACTT

>NZ_CP017690|1|1|42610-43634|CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGCTCTCTCTAAAATAGCTATTTGCCTGGACATTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAAACACCCCCTTGCACGTTTTGTACACATTTTTCCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCGGGTAAATGTGTACATTTTGTACATGTGGAGGTAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGTATGACGATCTCGGCGCTTGGTTCGTATGTGATCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAATAAAAACTGACATGAAAACTGACATAAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GTAACTATTAGAAATGCTATAGCATCAATAAAACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATAGCCGCAGATAAAATGGCAGTTGGGACAGCCACAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCATCGGCAATGCATTGGCACCCGCGATTGAAAAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGAGCGAGCAGACGCGAGCGACGGAAGGGGGAGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAACATCCGCGTCCACCGCATGGCCAACAGCGAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CGCTCAACGGTACAGTGTTGACTATCGGTGATTTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGATTCATCTGCTGTACCAACCAACAAAACAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GATCGCCTGTAATACGATACTGGAACGTTACACCTGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGCAAATCCTAGCGGCGTTAGATCCAGAAGCGACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTGACGAGCATCCTGAAGTGGCCTGAGGGTTGA
ATTTTTATCGTACCTATAAGGAGTTCACTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017690.1\|WP_011887561.1\|30052_31768_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350
NZ_CP017690.1\|WP_020960056.1\|53051_53816_+\|urea-ABC-transporter-ATP-binding-protein-UrtD	unknown	unknown	gnl\|CDD\|274568
NZ_CP017690.1\|WP_050367343.1\|49795_51052_+\|urea-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|132448
NZ_CP017690.1\|WP_020755308.1\|54580_54886_+\|urease-subunit-gamma	unknown	unknown	gnl\|CDD\|183913
NZ_CP017690.1\|WP_020960058.1\|51113_52007_+\|urea-ABC-transporter-permease-subunit-UrtB	unknown	unknown	gnl\|CDD\|200272
NZ_CP017690.1\|WP_008879985.1\|36971_38423_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP017690.1\|WP_020960055.1\|53794_54496_+\|urea-ABC-transporter-ATP-binding-subunit-UrtE	unknown	unknown	gnl\|CDD\|274567
NZ_CP017690.1\|WP_020960061.1\|46641_47991_+\|GntP-family-permease	unknown	unknown	gnl\|CDD\|308194
NZ_CP017690.1\|WP_060475923.1\|33365_34697_+\|GntP-family-permease	unknown	unknown	gnl\|CDD\|225330
NZ_CP017690.1\|WP_008879987.1\|40812_41256_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP017690.1\|WP_099232721.1\|38716_40807_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP017690.1\|WP_081157268.1\|48108_49506_+\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NZ_CP017690.1\|WP_008879983.1\|34713_36174_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NZ_CP017690.1\|WP_157663119.1\|36603_36762_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_099232725.1\|44962_46507_+\|xylulokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP017690.1\|WP_011887551.1\|43929_44934_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP017690.1\|WP_099232719.1\|32147_33335_+\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341473
NZ_CP017690.1\|WP_081157260.1\|28533_29538_+\|C-terminal-binding-protein	unknown	unknown	gnl\|CDD\|240624
NZ_CP017690.1\|WP_081157276.1\|52018_53077_+\|urea-ABC-transporter-permease-subunit-UrtC	unknown	unknown	gnl\|CDD\|132449
NZ_CP017690.1\|WP_099232723.1\|41255_42419_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031

Protein	Function_ID	Function_description	E-value
NZ_CP017690.1\|WP_011887561.1\|30052_31768_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	5.81016e-176
NZ_CP017690.1\|WP_020960056.1\|53051_53816_+\|urea-ABC-transporter-ATP-binding-protein-UrtD	gnl\|CDD\|274568	TIGR03411, urea_trans_UrtD, urea ABC transporter, ATP-binding protein UrtD. Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	9.51675e-150
NZ_CP017690.1\|WP_050367343.1\|49795_51052_+\|urea-ABC-transporter-substrate-binding-protein	gnl\|CDD\|132448	TIGR03407, urea_ABC_UrtA, urea ABC transporter, urea binding protein. Members of this protein family are ABC transporter substrate-binding proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. Members of this protein family tend to have the twin-arginine signal for Sec-independent transport across the plasma membrane. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_CP017690.1\|WP_020755308.1\|54580_54886_+\|urease-subunit-gamma	gnl\|CDD\|183913	PRK13241, ureA, urease subunit gamma; Provisional.	6.84014e-70
NZ_CP017690.1\|WP_020960058.1\|51113_52007_+\|urea-ABC-transporter-permease-subunit-UrtB	gnl\|CDD\|200272	TIGR03409, urea_trans_UrtB, urea ABC transporter, permease protein UrtB. Members of this protein family are ABC transporter permease proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	1.13376e-147
NZ_CP017690.1\|WP_008879985.1\|36971_38423_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP017690.1\|WP_020960055.1\|53794_54496_+\|urea-ABC-transporter-ATP-binding-subunit-UrtE	gnl\|CDD\|274567	TIGR03410, urea_trans_UrtE, urea ABC transporter, ATP-binding protein UrtE. Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	1.19443e-130
NZ_CP017690.1\|WP_020960061.1\|46641_47991_+\|GntP-family-permease	gnl\|CDD\|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	3.2011e-173
NZ_CP017690.1\|WP_060475923.1\|33365_34697_+\|GntP-family-permease	gnl\|CDD\|225330	COG2610, GntT, H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism].	2.42964e-56
NZ_CP017690.1\|WP_008879987.1\|40812_41256_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	1.32546e-59
NZ_CP017690.1\|WP_099232721.1\|38716_40807_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	2.16476e-65
NZ_CP017690.1\|WP_081157268.1\|48108_49506_+\|chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	2.94685e-32
NZ_CP017690.1\|WP_008879983.1\|34713_36174_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_CP017690.1\|WP_099232725.1\|44962_46507_+\|xylulokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP017690.1\|WP_011887551.1\|43929_44934_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	8.2384e-113
NZ_CP017690.1\|WP_099232719.1\|32147_33335_+\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341473	cd08194, Fe-ADH-like, Iron-containing alcohol dehydrogenases-like. This family contains iron-containing alcohol dehydrogenase (Fe-ADH) most of which have not been characterized. Their specific function is unknown. The protein structure represents a dehydroquinate synthase-like fold and belongs to the alcohol dehydrogenase-like superfamily. It is distinct from other alcohol dehydrogenases which contain different protein domains. Alcohol dehydrogenase catalyzes the reduction of acetaldehyde to alcohol with NADP as cofactor. Its activity requires iron ions.	0
NZ_CP017690.1\|WP_081157260.1\|28533_29538_+\|C-terminal-binding-protein	gnl\|CDD\|240624	cd05299, CtBP_dh, C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor. The transcriptional corepressor CtBP is a dehydrogenase with sequence and structural similarity to the d2-hydroxyacid dehydrogenase family. CtBP was initially identified as a protein that bound the PXDLS sequence at the adenovirus E1A C terminus, causing the loss of CR-1-mediated transactivation. CtBP binds NAD(H) within a deep cleft, undergoes a conformational change upon NAD binding, and has NAD-dependent dehydrogenase activity.	4.86976e-171
NZ_CP017690.1\|WP_081157276.1\|52018_53077_+\|urea-ABC-transporter-permease-subunit-UrtC	gnl\|CDD\|132449	TIGR03408, urea_trans_UrtC, urea ABC transporter, permease protein UrtC. Members of this protein family are ABC transporter permease proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	1.26216e-159
NZ_CP017690.1\|WP_099232723.1\|41255_42419_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0

>NZ_CP017690.1|WP_099232723.1|41255_42419_+|mannitol-1-phosphate-5-dehydrogenase
MRAVHFGAGNIGRGFIGSLLAASGYDVVFVDVNEQIVRLLKEQGEYRVIIAGERQEEQWVRGVSALNSQTERDDVIEAIASADLVTTAVGPHILPVIAPVIAAGLERRFTVHQKPLHVIACENMIGGTETLKQHVVTHLSEAGRQLVEECVGFLNCAVDRIVPNQTNDDPLAVTVEPFFEWAIETKNTIGAVPPIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYQKQYRTVQEAMKDSGIRESVEQALRESGAVLVKKHGWDEQEHRSYIETTIGRFTNPSLSDDIVRVARSPIRKLGPNDRLVAPAVQYYTLFERVPSGLVKGIAALLLFDETGDAEATALQKTIEQSGVEGALVQYAGLDNSHPLVVAVKEEYAQMKQMYSR
>NZ_CP017690.1|WP_008879987.1|40812_41256_+|PTS-sugar-transporter-subunit-IIA
MLAYSILKKENIVLNAQPKTKEEAIRLAGEVLVKQGYVDPSYIDAMLEREQLTTTYIGNNVAIPHGTEEAKSLVKQSGISIVQVPGGVDFGGGNQATIVIGIAGKDGEHLDILSKLALVCAEADNVAAMANAKTAEEILTLLNEVNG
>NZ_CP017690.1|WP_099232721.1|38716_40807_+|BglG-family-transcription-antiterminator
MYVSARERKLLERLLVGGREITVGELAEELNVSTRTIHRDLQGLESVLRHYGLELEKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPVKLVSLANDLNVTVATVSLDLDKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLFRHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKLAIIEKQIEQVKEKLPFTMADSSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKEEIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLLDQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFAAALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVMEQASVFELKKKDLRAYDLVISTVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAVRRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGLGVPGTKLALYHARSFSVLRPSLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEMLSVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFFDHYWTTTKE
>NZ_CP017690.1|WP_008879985.1|36971_38423_+|PTS-mannitol-transporter-subunit-IICB
MTHTTGNETGFRVKIQRFGSYLSGMIMPNIGAFIAWGLITALFIPTGWWPNETFAKLVGPMITYLLPLLIGYTGGKMIYDVRGGVVGATATMGVIVGSEIPMFLGAMIMGPLGGYVMKKVDALFQGKVKQGFEMLVNNFSAGIIGALLTLLAFKGIGPVVTAISKTLASGVEKIIDWHLLPLASIFIEPGKVLFLNNAINHGILSPLGVEQAAQTGKSILFLLETNPGPGLGILLAYCLFGKGMAKQSAPGAAIIHFLGGIHEIYFPYILMRPILMLAVIAGGVSGVFTFTVLHAGLVAVPSPGSIFALLAMTPKGNYFSVLAGVFVATAVSFLVASICLKTAKQNEEEEDLTKAAEKMEQLKGKKSQVAATLQQKDEAASAGVASAVPDRVKKIVFACDAGMGSSAMGASILRNKVQKAGLSIEVTNTAINQLPADADIVITHQNLTDRAKAKLPNAYHVSVENFLNSPKYDELIEQLKQNA
>NZ_CP017690.1|WP_157663119.1|36603_36762_+|hypothetical-protein
MMIGEKAFDTEWSLMSRWLECYLNDFPYGQAAQLGFDSQENNRSEVAVRHFA
>NZ_CP017690.1|WP_008879983.1|34713_36174_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MSSVTETKTLKNFIGGQWVASTSGKEEIVPNPATGEVLAKVPISSREELDAAVAAAKEAFREWRKVPVPRRARILFRYQQLLVEHWEELARLVTLENGKVYEDAYGEVQRGIECVEFAAGIPTLMMGQQLPDIATGIESGMYRYPLGVVAGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPLLANRLAELFTEAGLPAGVLNIVHGAHEVVNGILEHKDIKAVSFVGSQPVAEYVYKTAAAYGKRVQALAGAKNHSIVMPDADLDMAVTNIINAAFGSAGERCMACSVVVAVGDIADELVERLKKAADRIQIGNGLDQGVFLGPVIRESHKERTIKYIEIGEREGALLVRDGRRDAATSGKGYFVGPTIFDHVKPGMTIWTDEIFAPVLSVVRARDLDEAIEIANRSEFANGACIYTDSAKAIRQFREEIDAGMLGVNVAVPAPMAFFPFSGYKNSFYGDLHANGRDGVEFYTRKKMVTARH
>NZ_CP017690.1|WP_060475923.1|33365_34697_+|GntP-family-permease
MLGMIGLLASLGLLIFLTMRGINIIIAALISSILVALTGGLNLEKALMESYMTGFTGYFASWFLIFLAGAIFGKVMEDTGSADSIAHWVKEKFGAKHAVLAVVAACAIMTYGGVSLFVVGFSVYPIAVSLFRQSNTPHRFIPAAMVFGSVSFTMTSPYSPEIQNIIPTQFFHTTPGAGGWVGLFVGATIAVTGSLYLTRVVQKAKQNGETFSLPYRTDDISGEVSEVAASIEQGAGRPLPNIVCAMLPLVVVIVSLNILAKFISSTSAGVASLILGIVLCWVLNAKFVRKFWESMASGTQDALVAAANTCAVVGFGEVAKNVPAFQKAVDVLVNIPGPELLGLGLAVTIICGMTGSASGGLGIALPILAPIYMAKGLDPGAMHRVAALASGGLDSLPHNGYIVTTIRAVCHETHERTYKPIFVLSVVIPLAGMFLAILLYSIF
>NZ_CP017690.1|WP_099232719.1|32147_33335_+|iron-containing-alcohol-dehydrogenase
MYELLVPNRVIYGRDTFREVGRQAKTLGTKALIVSDPVMENIGLVARCEQYLREAGLPLATYTRVDTEPTDVHVKEALDVCRSEQCDVIVAIGGGSSIDAAKAVAVMMTNEGTISDYVGNAKMFTKKPVPLIAIPTTAGTGSEVTKVTVIIDTKTDVKMMISQPALLPAVAIVDPLLTVSCPPSVTAATGVDALCHSIEAYISRRAHPVTDVLALSAIEAIIGHLRRAYENGQDIEAREKMAIAAMKAGMAFSNASVTLVHGMSRPIGALFHVPHGVSNAMLLPGVLEFTKESATERLAVIARLINPQLKDVSDAEAADALVEEVKQLCRDLHIPNMKTWGIDKTAFDKAVDKMAADALASGSPSNNPRVPTHEEIVALYHICYDYRYDTNTVSR
>NZ_CP017690.1|WP_011887561.1|30052_31768_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MAISHGTSLVLGCHQTVQEAIQLFSEHGMAAVDVVDEHGRSVGRCTWRMLLRAIAKEMDRMALIGDVLAAFSMDGKTEPKEDSMETSDGEGDSGAAAELERLRRELEETHRLAETMKTVLDAAYEGVVVVDGNGMVREINRAYCQFLGIRREDAIGKHVTEVIENTRLHICVQSGIPERGYIQKIYGQPMVVHRIPIWRDGKVIGAVGMLIFQGVSEVYAIFQRLQELSREASRKEKNEAEASKQEAVASAAVGVERIIGRHPTIAAVKQMIRRAARVPSTVLITGESGTGKEVVARAIHEAGAHADGPFVSVNCAAIPEALLEAELFGYEDGAFTGAKKGGKPGKFQLAHGGTLFLDEIGDMPLAMQAKILRVLEEKKVEKVGGLSETEVDVRIIAATNKPLEEMVRDGTFREDLFYRLNIIRIHLPPLRERKTDIPALLAHHMERLCRQFGVVSKSFAKEAMEVLINYSWPGNIRELVNVVEWLISMVEGENIEREHLPAYLSTIHPSVTPMPDGGANIADQWKEIVYQSERERIAAALVAANGNKAEAARRLGIHRSTLYEKLKKYGF
>NZ_CP017690.1|WP_081157260.1|28533_29538_+|C-terminal-binding-protein
MKKYKVVVTDYEFQTLKPEQEVLSPLNVDFVVAQCYTEEEVIAVCKDADAIINQYAPISAKVIDQLEKCKVISRYGVGVNTVDVDVATEKGIIVANVTDYSVDEVSDHALALLLSLARKIVKLNDEVKSGVWNFNVGKPIYRLRGRTLGLVGFGRIPQALAKKAQSLGLYVIAYDPYIPAKVARQFNVHLVELNDLFRQSDYISVHAPLTKETKGMISDEQFHLAKKELIIVNTARGPVIDESSLIRALQDGKISGAGLDVTEYEPIHPDNPLLQMENVVITPHIAWYSEESEMELKRKTAQNVADVLSGCYPRYLVNPRVKEKVRLKVKESYV
>NZ_CP017690.1|WP_011887551.1|43929_44934_+|LacI-family-DNA-binding-transcriptional-regulator
MKKVTMADVAKLANVSKSTVSQYLNKRYEYMSEETRKRIAQAIEELGYQPNVIARSLKQKTTATIGVIVFNMLHMLTTQVLHAIEEECQKREFQVIVCNSGDDPEKERKYIDMLLAKQVDGLIVFPTGKNEDVYHRLVAERFPIVFVDRMVPGVEADSVLLDNFGAAEMAVDYLAAHGYDRIAIVTPPLVAHNVPRMERLQGFRMAMEKRGLKVDDRSVIAAEAAELPGELQKRFAAPERPNALFAINDLTLMGILRFVKETGIRVPDELGLISIDDVPFADIYTPMLTTIAQPTFAMGKKAAERVFEQMDQERTRKPRVFRFSPTLVERTSIR
>NZ_CP017690.1|WP_099232725.1|44962_46507_+|xylulokinase
MAISEDVVIGIDIGTTSTKAVVFGERGRVLASHAVDYPIIQPHPGFAEQDPEELFAAVIQAVGAVTVRHGIRPQQVKAIGLSAAMHSMMALDESGRPLTRLIIWADNRSVVQAERLLKEHHGLDIYRRTGTPIHPMSPLPKLLWLKEEEPDVFRQAHRFVSVKDYVLYRLYGDYVTDHSLASATGLFRLDTLDWDEDVLSLLGIGRERLPRLVPATHILQGMNKEWADKMGVSPDVPVVIGASDGVLANIGVGAVLPGEAAITIGTSGAVRTIATTPTTDEKGRTFCYALTPGYWVVGGPTNNGGILLRWLRDEFGAQEREVAKKLGVDPYDLLTKYAERVPPGAEGLVFLPFLSGERAPYWNANARGTFFGLGLHHKREHFIRAVMEGVCFSIVSVALAIRDVTGPMAEIRVSGGFAKSPFWRQMLSDMLGKPLIVPQTHEASALGAAAVALHALGEVPSLEMVKTWIDTTARHEPKEEHTLIYAELFDLYARLYERLKAEFDIIAAFQRRSG
>NZ_CP017690.1|WP_020960061.1|46641_47991_+|GntP-family-permease
MEIAIVVAAIIVLLLLITMAKMHPFVALILVSVGVGLAMGMPLIAPSPETPGIIDSIKAGLGNTLGFLAIVLALGTMLGKMMAESGGAERIAKTLIDRFGQKRVHWAMMVVAFLVGIPVFFQVGFVLLIPLVFTIAMETGISLVTIGIPLVAGLSVVHGLVPPHPAAMAAVGIFKADVGKTILYSIIVGLPTAIIAGPLYGKWIGSRLHKTVPAEIAEQLVQHKEARELPGFGNTLFTILLPVILMLIASVANVTLDQKSEAAKVLRFIGDPIVALLIATVYSFFSLGYARGFNRDAVLKFANDCLGPVANILLVIGAGGAFNKVLLDSGIGEQIAEVAKHSHFSPLLLGWGIAALIRVATGSATVSMMTAAGIVAPIAATMPGTNMELLVLATGAGSLILSHVNDSGFWMIKEYFGMTVKETLMTWTVMETIISVVAFVFILLLNMVL
>NZ_CP017690.1|WP_081157268.1|48108_49506_+|chemotaxis-protein
MIFARRAERKIKRELDQPRREETQGGPQQIARQIVVAVDQLKAAMEQMKMAALSLNDISDSSRNSAAELMDHSEKTVEYTEKVANKMRTIEEAAREIAASSRDMYASSQQFSEHWLHSWNSLETLQKEIRTLRSHHETLLEQMDHLVHHSRRINEIISAIGEISQKTKILSLNANIEAARAGEHGRGFAVVAREIGMLANQTSEAVQQTQDILSLIQREIAATTDIVREETKQIDVEEKEMEAIMAFLHSLQRQLNDMTDLVSSSVQSASGQSDSVKEIAGLLEEIVQLSRENQRFVERVTADMNEQHESVGQILRINEALQKTAEELQQTVGRDWMRETISVDDAVVKNTIQKLSALLQSAPLEQMDEAMHQRVLDRFLSENGEIEAVWSNRLDGAFVYSNPPAGLVNAKVRSWFQEACRGTVYVSDPYVSALTKHLCVTVSAPIRDHNGQIVGVIGVDLSLVK
>NZ_CP017690.1|WP_050367343.1|49795_51052_+|urea-ABC-transporter-substrate-binding-protein
MKPAFMWKLWLLLCVSVFALGGCAASSAVDQAKNENQNDSSSAGKEGDVVKVGILHSLSGTMAISEVSLRDAELMAIEEINASGGLLSKKIEPVVEDGASDWPTFAEKAKKLLQKDQVAAIFGGWTSASRKAMLPVVEQNNGLLWYPVQYEGMESSPNIFYTGATTNQQIVPAVSWLLKNRGKTFFLLGSDYVFPRTANKIIKAQLKAEGGQVVGEEYTPLGHTDYSTIISKIKQVKPAVVFNTLNGDSNVAFFKQLKDAGITPKDVTVMSVSIAEEEIRGIGPDVLAGHLAVWNYFQTTDTPENKAFVQKYKEKYGQDRVTDDPIEAAYTAVHLWAEAVKKAGSFDVDQVKKAAAGLEYKAPEGTVKIDGETQHLWKTVRIGEIQADGQFKELWNSGQPVKPDPYLKSYPWGKGLSE
>NZ_CP017690.1|WP_020960058.1|51113_52007_+|urea-ABC-transporter-permease-subunit-UrtB
MFIDQLFNGLSVGSILLLIAIGLAITFGLMGVINMAHGELMMVGAYTTYVIQQIFAHHAPQSAGMYFVIAIPSSFLIAALLGWGLEKSLIRHLYHRPLDSLLATWGISLILQQTARLIFGAPNVAVVPPSWLDGGIRLFGAVFPYKRLFILCLVLAIVFFLYMYLTRTRAGRRIQAVTMNRPMAACLGIATQKVDAYSFAIGSGLAGVAGCALTLLGPIGPTIGTYYIVDAFMVVILGGVGKLAGTLLGAFGLGLISTFVEYSTSATIAKVIVFVLIIAFLQWKPSGLLSLRTRSLD
>NZ_CP017690.1|WP_081157276.1|52018_53077_+|urea-ABC-transporter-permease-subunit-UrtC
MVNKRWGYWLFFVALFLAPFYLTEFRLSLLGKFLCFAIVAVGISLIWGYTGILSLGHGVYFGLGAYCMAMYLKLEASRGHLPDFMEWSSVRELPWFWKPFAHPVVAVIAAIVLPTLLAALLSYFTFKNRIQGVYFSLLSQAVVVVFVTLFIGKQEWTGGTNGLTNFSTVFGFSLSSPLTQIVLYWLTAAVLALIFVMTRRLTTGRLGKVLIAIRDAENRVRFLGFNPTVYKVFVYSLSAAFAGVAGALFVLQVGLISPEMMGIIPSIEMVLWAAVGGRHSLMGAIMGAIVMNTAKSFLSENYPDLWLLLLGALFVVVVLFVPKGLAGIYESLAAVRIKEKRGHECEARVDVS
>NZ_CP017690.1|WP_020960056.1|53051_53816_+|urea-ABC-transporter-ATP-binding-protein-UrtD
MKPVLMCRDVVVDFDGFRALQGVDLAVYPHEVRFLIGPNGAGKTTLLDVICGRTRATDGRVLFFFHDITQRPEYEIVQIGIARKFQSPSIFPFLTVWENMELAMRQDRRLRSVLRAKLTGEEKEMMAAQLEKIGLLDERHRLAGSLSHGQKQWLEIGMQLIQRPQLLLLDEPIAGMSAAERERTGEWLHEMAEHCAVIIVEHDMDFVRRYSKQVTVMHEGKVLCEGSMDEVQQNEQVIDVYLGRGKNACCASGM
>NZ_CP017690.1|WP_020960055.1|53794_54496_+|urea-ABC-transporter-ATP-binding-subunit-UrtE
MLRLRDVTAGYDGSVVLDHVDMDVPLGRVTAVLGRNGVGKTTLMKTIIGLIRPMSGVIEWEGEDITRWPPERRARAGIGYVPQGREIFSALTVEENILLGLEAQAEKVRPQPTLDEMYALFPILKEMRQRKGGDLSGGQQQQLAIARALAGRPKLLLLDEPMEGIQPSIVALIHDAIMKIAKEKQVGIILVEHNVELAFSCADRFYILDRGAVVAKGDVDGADLTYIQSFLAV
>NZ_CP017690.1|WP_020755308.1|54580_54886_+|urease-subunit-gamma
MKLTPREQEKLLIVVAADLARRRKERGLKLNYPEAVALITYELMEGARDGRTVAELMQYGATILTRDDVMEGVADMIDEIQVEATFPDGTKLVTVHQPIRS

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Crispr_ID: NZ_CP017690_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017690_2

630126-630309

Orphan

Consensus_repeat	Method
GTTTCAATCCTCTAAACGAGGCCTTTCTCTTTCAACA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP017690_2

>merge|NZ_CP017690|2|630126-630309|CRISPRCasFinder
AGTAGAATCCTTTAAACGAGGCCTTCCTCTTTCAACACTTCAATCTTCCAGAGGGTCTATCTGCGGAAGAATAGTTTCAATCCTCTAAACGAGGCCTTTCTCTTTCAACACGATTATTATTGTGAAGAATTGCGACCGCTTAGATGTGTTTCAATCCTCTAAACGAGGCCTTTCTCTTTCAACA

>NZ_CP017690|2|2|630126-630309|CRISPRCasFinder
AGTAGAATCCTTTAAACGAGGCCTTCCTCTTTCAACA	CTTCAATCTTCCAGAGGGTCTATCTGCGGAAGAATA
GTTTCAATCCTCTAAACGAGGCCTTTCTCTTTCAACA	CGATTATTATTGTGAAGAATTGCGACCGCTTAGATGT
GTTTCAATCCTCTAAACGAGGCCTTTCTCTTTCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017690.1\|WP_008879448.1\|643452_644403_-\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl\|CDD\|226964
NZ_CP017690.1\|WP_087959962.1\|617649_619743_-\|beta-N-acetylhexosaminidase	unknown	unknown	gnl\|CDD\|366376
NZ_CP017690.1\|WP_011887242.1\|644395_645352_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NZ_CP017690.1\|WP_008879443.1\|634482_635154_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NZ_CP017690.1\|WP_060475794.1\|628535_629972_-\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|225100
NZ_CP017690.1\|WP_008879431.1\|615309_616218_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176125
NZ_CP017690.1\|WP_011887248.1\|619768_621478_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP017690.1\|WP_060475793.1\|633205_634486_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373965
NZ_CP017690.1\|WP_008879435.1\|621847_622834_-\|acryloyl-CoA-reductase	unknown	unknown	gnl\|CDD\|176249
NZ_CP017690.1\|WP_172437874.1\|646227_647895_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP017690.1\|WP_029760927.1\|628094_628403_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_008879441.1\|630636_633261_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|350770
NZ_CP017690.1\|WP_060475795.1\|624647_626264_-\|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|377939
NZ_CP017690.1\|WP_011887243.1\|637423_641194_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|224037
NZ_CP017690.1\|WP_008879447.1\|642703_643459_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226963
NZ_CP017690.1\|WP_008879436.1\|623071_624424_-\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|181078
NZ_CP017690.1\|WP_029760926.1\|626486_627878_+\|GABA-permease	unknown	unknown	gnl\|CDD\|273797
NZ_CP017690.1\|WP_008879444.1\|635150_637097_-\|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP017690.1\|WP_011887250.1\|616377_617634_-\|DUF1343-domain-containing-protein	unknown	unknown	gnl\|CDD\|377768
NZ_CP017690.1\|WP_008879446.1\|641488_642448_-\|siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|226966

Protein	Function_ID	Function_description	E-value
NZ_CP017690.1\|WP_008879448.1\|643452_644403_-\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl\|CDD\|226964	COG4605, CeuC, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.16605e-125
NZ_CP017690.1\|WP_087959962.1\|617649_619743_-\|beta-N-acetylhexosaminidase	gnl\|CDD\|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	6.7777e-126
NZ_CP017690.1\|WP_011887242.1\|644395_645352_-\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.17237e-143
NZ_CP017690.1\|WP_008879443.1\|634482_635154_-\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	9.51227e-23
NZ_CP017690.1\|WP_060475794.1\|628535_629972_-\|site-specific-DNA-methyltransferase	gnl\|CDD\|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	2.56718e-39
NZ_CP017690.1\|WP_008879431.1\|615309_616218_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176125	cd08434, PBP2_GltC_like, The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold. GltC, a member of the LysR family of bacterial transcriptional factors, activates the expression of gltA gene of glutamate synthase operon and is essential for cell growth in the absence of glutamate. Glutamate synthase is a heterodimeric protein that encoded by gltA and gltB, whose expression is subject to nutritional regulation. GltC also negatively auto-regulates its own expression. This substrate-binding domain has strong homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.34311e-72
NZ_CP017690.1\|WP_011887248.1\|619768_621478_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	5.74044e-80
NZ_CP017690.1\|WP_060475793.1\|633205_634486_-\|hypothetical-protein	gnl\|CDD\|373965	pfam15611, EH_Signature, EH_Signature domain. This domain with a strongly conserved glutamate at the N-terminus and a histidine at the C-terminus, is found in a SWI2/SNF2 four gene operon. Its strict-neighborhood association with SWI2/SNF2 ATPase strongly suggests a function in conjunction with it. The other genes in the operon are a OmpA protein and a TM protein. This has a DNA related function along with the TerY-P triad.	0.000627533
NZ_CP017690.1\|WP_008879435.1\|621847_622834_-\|acryloyl-CoA-reductase	gnl\|CDD\|176249	cd08289, MDR_yhfp_like, Yhfp putative quinone oxidoreductases. yhfp putative quinone oxidoreductases (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_CP017690.1\|WP_172437874.1\|646227_647895_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.01312e-26
NZ_CP017690.1\|WP_008879441.1\|630636_633261_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|350770	cd18012, DEXQc_arch_SWI2_SNF2, DEAQ-box helicase domain of archaeal and bacterial SNF2-related proteins. Proteins belonging to SNF2 family of DNA dependent ATPases are important members of the chromatin remodeling complexes that are implicated in epigenetic control of gene expression. The Snf2 family comprises a large group of ATP-hydrolyzing proteins that are ubiquitous in eukaryotes, but also present in eubacteria and archaea. Archaeal SWI2 and SNF2 are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	7.27386e-81
NZ_CP017690.1\|WP_008879447.1\|642703_643459_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226963	COG4604, CeuD, ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism].	5.27374e-153
NZ_CP017690.1\|WP_060475795.1\|624647_626264_-\|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	3.74085e-44
NZ_CP017690.1\|WP_011887243.1\|637423_641194_-\|AAA-family-ATPase	gnl\|CDD\|224037	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair].	4.92332e-28
NZ_CP017690.1\|WP_008879436.1\|623071_624424_-\|aspartate-aminotransferase-family-protein	gnl\|CDD\|181078	PRK07678, PRK07678, aminotransferase; Validated.	0
NZ_CP017690.1\|WP_029760926.1\|626486_627878_+\|GABA-permease	gnl\|CDD\|273797	TIGR01773, GABA_permease, gamma-aminobutyrate permease. GABA permease (gabP) catalyzes the translocation of 4-aminobutyrate (GABA) across the plasma membrane, with homologues expressed in Gram-negative and Gram-positive organisms. This permease is a highly hydrophobic transmembrane protein consisting of 12 transmembrane domains with hydrophilic N- and C-terminal ends. Induced by nitrogen-limited culture conditions in both Escherichia coli and Bacillus subtilis, gabP is an energy dependent transport system stimulated by membrane potential and has been observed adjacent and distant from other GABA degradation proteins. GabP is highly homologous to amino acid permeases from B. subtilis, E. coli, as well as to other members of the amino acid permease family (pfam00324). A member of the APC (amine-polyamine-choline) transporter superfamily, GABA permease possesses a "consensus amphiphatic region" (CAR) found to be evolutionarily conserved within this transport family. This amphiphatic region is located between helix 8 and cytoplasmic loop 8-9, forming a potential channel domain and suggested to play a significant role in ligand recognition and translocation. Unique to GABA permeases, a conserved cysteine residue (CYS-300, E.coli) located at the beginning of the amphiphatic domain, has been determined to be critical for catalytic specificity. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_CP017690.1\|WP_008879444.1\|635150_637097_-\|MotA/TolQ/ExbB-proton-channel-family-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.06475e-05
NZ_CP017690.1\|WP_011887250.1\|616377_617634_-\|DUF1343-domain-containing-protein	gnl\|CDD\|377768	pfam07075, DUF1343, Protein of unknown function (DUF1343). This family consists of several hypothetical bacterial proteins of around 400 residues in length. The function of this family is unknown.	0
NZ_CP017690.1\|WP_008879446.1\|641488_642448_-\|siderophore-ABC-transporter-substrate-binding-protein	gnl\|CDD\|226966	COG4607, CeuA, ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism].	3.87088e-137

>NZ_CP017690.1|WP_060475794.1|628535_629972_-|site-specific-DNA-methyltransferase
MANGGRRTKGAVSARLERVKELFPEVVAGEAIDWERLKKELGYEEQDEVYGFTWPGKAGAKQLAETPAIGALRPDRAASKRWETTNNWYIEGDNLEALKLLRASHEGSVQMIYIDPPYNTGKAFTYKDNWRKRKRAASHIEQEEARVHAGWLNMMYPRLWVAKALLAETGAIFISIDDTEQANLKKMCDEIFGERNFVATFIWQRAFSPVNMNKFASRNHDFILCYAKNIDRLAWYGLPRDSEANGRYANPDNDPRGPWMSGDLSVGPPIPEKIYDIVTPGGRVVSPPSGYCWRVTKERFAELAADNRIWFGKDGNGVPRLKRFLREVKPTMTPLTIWTHDEVSHSQEAKKELKELFDGMAVMDYPKPVKLIQRMVALTTKDDDVILDFFSGSATTAHAVMQQNAEDGGQRSFIMVQLPERMVKTSAAYQAGFRTICDIGRERICRAGEKIIRETGKIDLDIGFKVFQIERKSKQPAR
>NZ_CP017690.1|WP_029760927.1|628094_628403_+|hypothetical-protein
MIVHELMDMEHLFVEQLQEGYYIIHETYQNVLVEPEDGDAVRQVDAGTEEVVTILFDPGNEYSLLCLDTYTFAGDMPSLTELKETIAAEYDVFVNNDHAASL
>NZ_CP017690.1|WP_029760926.1|626486_627878_+|GABA-permease
MNHSGLQKGLKERHMTMIAIAGVIGAGLFVGSGAVIHSTGPGAIVSYALAGALVVLVMRMLGEMAAARPTSGSFAAYAHEAIGPWAGFTVGWLYWFFWVIVIAIEANAGAAIIQYWFPSIPLWLLSLVLTILMTLTNIWSVKSYGEFEYWFAFIKVASIVLFLILGLAFIFGLAPGSEPVGLKNLTGHGGFMPHGIGSILVGIVIVIFSFFGTEIVTIAAGESAEPQEAVSKATKSVTWRILVFYIGSIAVVVTLLPWNSASVLKSPFVAVLEHVGVPAAAQIMNFIVLTAVLSCLNSGLYTTSRMLYSLAEKGEAPKSFLRLNKNGVPVRAVIASTLFAYIAVIMNYVSPDKVFLFLVNSSGAIALLVYLVIAVSQLRMRQKLERENSTALKIKMWLFPYLTYFTILALLVILASMLFIESMISQLLLTLLITAVVIVYYFVFARRHLNPNYQPATPTPAKD
>NZ_CP017690.1|WP_060475795.1|624647_626264_-|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein
MGYGFPLTVADVLQRKYFQKAVVIAGKEGLSRTVKWVHVVEVTKISNLLRGKELILSTGVGWREDDSLFLSLLRQLIECDASGLCIELGTYASSIPKEALELANRHHFPLILFLEEVPFVEITHDIHTYLINQQYQMIAQLESYSQELNKKLLTVHHYREILTFLHSCLGHQVVFHMHGGDVEYIPSRPRGNLGAGVGLGGESDWPSAAVVKPISLFGAEYAELALLPVGRDINEFDLLILDRTATALAQHLLRNLYVEERRRTEENEWLKGWIEGEYSDQEISSYLLDHHPSLHSRGGVVWVCKVGTAGQKGNFDSTYFKLLCRSLFEQRGFLLFSVEMGRHLAFIAINLRDEETWKSRIEEGIKCLMASDFMQTRLSALPVGVGTFAPSLSSINQSYRAALEALKIRSRLDEQGASLFYDDLHLYRMIMVLDKYSDLREAINRYLGPIIEYDRKYNGKLLETLKVYLQCNGSKQEAAKRLFIVRQTLYHRIEKLESFLGDNFMEANKRLAIELMIKAYDYLMGDGEALYAQRNAQL
>NZ_CP017690.1|WP_008879436.1|623071_624424_-|aspartate-aminotransferase-family-protein
MKTEQSHQLWLDKDDRYIWHSMKPYNPNATVVVTEAKGCWVTDVAGNKYLDAMAGLWCVNVGYGREELAEAAYEQLKTLPYFPLTQSHLPAIQLGEKLNELLGDEYVIFFSNSGSEANETAFKIARQYHQQRGEPHRYKIISRYRAYHGNSMGALAATGQAQRKYKYEPLAPGFIHVPPPDRYRDPDAADDPRQLRAVKAVDDVMTWELSETIAAMIMEPIITGGGVLMPPDGYMKAVKEVCEKHGALLIVDEVICGFGRTGKPFGFMHEGIKPDIITMAKGITSAYLPLAATAVRKEIYEAFKGTDEYDYFRHVNTFGGHPASCALALKNIEIMETEHLFDRSREAGEWLLSALKTKLADHPYVGDVRGRGLLVGIELVADQTTKEPLDVSLVNQVISRCKEHGVIIGKNGATVAGYNNVLTLSPPLCISDDELSFLVRVLTEALAQIK
>NZ_CP017690.1|WP_008879435.1|621847_622834_-|acryloyl-CoA-reductase
MPTFQAFVVNKTEAEFTAGVETLSMDDLPEGDVVVRVHYSSVNYKDGLASIPDGKIVKTYPFVPGIDLAGIVVSSNDARFREGDEVIATGYEIGVTHFGGYSEYARLHGDWLVPLPKGLTLREAMAIGTAGFTAALSIHRLEELGLVPERGPVLVTGATGGVGSLAVSMLAKRGYTVAASTGKATEHDYLRALGAKEVLTREDVTAERIRPLDKQRWAAAVDPVGGRTLATVLSRIRYGGAVAVSGLTGGVEVPTTVHPFILRGVSLLGIDSVYCPMDLRLRIWEQLASDLKPDLEQIVHEISLHELPGALARILRGELRGRTVVRLV
>NZ_CP017690.1|WP_011887248.1|619768_621478_-|serine-hydrolase
MDKRPVFMILSSILFGSVLFCSPVAATSHHDPTPTIESAEIKAYKTSQSHRKASFSWDQKGSISAVIHPGTPQAAGMREAPLRKIDEVITQAMRDNVISGAVVYIVRRGMIVKQKAYGYAKQYEDDTFTQSKQPIPMRMDTMFDLASISKLFTTTAAMKLYEQGKFSLDDPVAKYIPEFAQNGKENVTIRQLMTHTSGLAAWIPLYTMGTNRDDRLQIVFAQPLEHPPGTTYVYSDLNMITLGALVERLSGVRLDQFVYRYITKPLGMNNTMYNPPLLKKRRIAATEYQPWTGRGMVWGEVHDENAWALDGVAGHAGLFSTARDLAIFASMFLQNGTYGGKRILQPETVQLLMENQIPQFPGYDHGLGWELAQGWYMDALSEHTSFGHTGYTGTSIVVNPNNDVIAILLTNRVHPTRNTPSINPLRRQVSRLTADAIPVAIPGKKAAWFAGYGDHLNAILSTKVVARKQLTLTFDTWYRMEPDVDFGVVEVSQDGEHWRQVGEQLTGSSDWTTKTVPIPAHTVAIRFRYCTDSSVNGRGWYVTNIRLVDDDGKELETLWESHDWERRTF
>NZ_CP017690.1|WP_087959962.1|617649_619743_-|beta-N-acetylhexosaminidase
MSFYWKTAVFMTVITFFISWASPQVGAKEKVGVDLIIYQNIPEVDVTIDGNTVALRALKVYPKGNFSEVTTGVQWKSSNRQVASVSRNGTVVFSGKSGKTFITVTDGVRKDRIGFTVKPVSAAKKGGKSDIKVSVSKEKGSRYDVISRAVKGLTLEEKIGQMLMPDFRYFNGAPVTAMRPEIKELIQKYHIGGIILFRENVVTTEQTARLVMDYQQAAEKFGLLISIDQEGGIVTRLQSGTNMPGNMALGATRSESLAYKVGHAIGEELYALGINMNLAPVLDVNNNPDNPVIGVRSFGENPELVAQLGTAYMKGLQDSGVAATAKHFPGHGDTAVDSHLGLPEVPHDRSRLETVEWYPFQKAMEAGIDAVMTAHVTFPKIDDTKVISQKDGTEISLPATLSHKVLTELMRQEMGFQGVIITDAMNMKAISDHFGPVDAAVRAVQAGADIVLMPIGLEEVASGLKKAVENGEISQERIDQSVKRILTLKVKRGIFKQETPPNEQEVIDRALRVVGSEEHKQTEREAAAKSITLVKNEQVLPLSPSKIDHLVVVGNTMIESLAEAVRAYVSNVTVIQGAAPLNEEQLQSVKKADAVIVGTYTSNASERLPSNPQMKMVRQMIDNTDAPVIAIGIRNPYDMMSYPDVEAYLAQYGFQPASFQAVVDVIFGINMPTGRLPVTIPRYDGGILYEYGHGLSY
>NZ_CP017690.1|WP_011887250.1|616377_617634_-|DUF1343-domain-containing-protein
MKKKWWMMFSLILLSLFMFTDALAKAPKKKEHPQLELGIEVLLKEQKKLIKGKRIGLITNPTGVDRDLNSSVDLLYNDRDVELVALYGPEHGVRGSAQAGEYVPFYIDEKTGLPVYSLYGPTKKPTPEMLKGVDILLFDIQDVGARFYTYIYTMAYAMEAAKENNIPFIVLDRPNPLGGVKVEGPVLETDYSSFVGMYPIPLRHGMTVGELALLINKEFGIDADVTVVKMKGWKRSMYYDDTGWQWVLPSPNMPTLDTALVYPGTALFEGTNVSEGRGTTKPFELIGAPFIDGLQLAEKLNALRLPGVRFRPASFQPTFSKYSGTLVHGVQIHVTDRQVFRPVETGVAMVKTIHDLYPDQFAFRAEDSQGISYFDQLIGNGWVRKAIEEGMTMEQMKKRWEKDVEAFHKKRERYLLYK
>NZ_CP017690.1|WP_008879431.1|615309_616218_+|LysR-family-transcriptional-regulator
MELRQLLYFVEVAKREHVSEAADALHVAQSAISRQIANLETELGVQLFEREGRNVKLTPIGRHFLPHAEAVLKAIDDAKQQIEEYLDPERGTIKIGFPTSLASQMMPMVISAFKAEHPNVSFHLRQGAYRYLIEAVKKREIDLAFLGPIPAREIGIKGEILFSEPFFVLLPNSHPLARRDRIVLNELRNDPFVTFPKGYILHQILIEACHQAGFVPNVSSEGEDLDAIKGLVSAGIGVTLLPESALSESLLRYAAKVPLEMPQVKRNVGIIISDHHELAPSVKVFYQFVKDFFSELERYQLG
>NZ_CP017690.1|WP_008879441.1|630636_633261_-|DEAD/DEAH-box-helicase
MFFFKKKQKMMKAVLTPNEDGVHLSFQLHDGKTVTELQLPMAKEEIENYYKLQGFPQYIAWEELYDSGVLVDSTLPYREYYELLKDESAKEVLQHLGLPNVEEQVSGKLSLRSLPHEADLVLQLFDANGRNLDRIGKQAGAIYVLPDRLMLLPERVYRLKQALLESYESGYEKIGICQQLANEAGIELENFLQNETYHVVDTYDVDVAVHRHDHIELVVKGRDEEETRHLQQLQRVSSVKKGHGRSRFVSTKQVHADMMHLQQKRHITGEEVPLFLENPAAVLPEHDYLFDLDQFSERVRGLIPIERVRPFFHERTGMQWFDEESGHAVPYDEAFLRELMEQYPDQQYVEYNGKWIYLDPLLRRKLLQLPKDADEALKRRYILDIKDNEEQLEYKIDSVRETSFRRYPVPSELQAALFPHQMEGFEWLCHLAEQERGGLLADDMGLGKTIQVIAFLLHQKANGSLKPTLIVLPIALIENWVAEIEKFAPSLLDSLYIHKGSERLASSQLISQFDIILTSYDTLKIDQLLLGKIEFQAIICDEAQNIKSHTSQRSRAIRAMQGRFRLAMTGTPVENSLDELWAIMDFVQPGALGSLKEFRFRYTETSDYDALLMAIQPYYLRRTKQQILDGRLPKKHLVPPIYVEASPIQKEIARSMLATKESGQVAILNMITRLRQLYGHPGAIIPKYEQLSYKEVPKLKETMHIIEAIRQKGEKALIFTEFRKLHFLLKRIFMETYGISVPVIDGDTKNRQLIVQHFNETQGFGIMILSPKAAGVGLTITSANHVIHYTRWWNPAVENQATDRAYRIGQQKDVYVYHIITRDSSHFPQGTVEELMHELLESKRHLAENVIIPFNISEIQQAVAEKVVEQRQLV
>NZ_CP017690.1|WP_060475793.1|633205_634486_-|hypothetical-protein
MKYEYEPVLLKRWLREPRPPLLEKTIENSNEKYRGVLERLSDQFAGLVHAPASAFQQWVKQLSRREKLLLPNLYKKELPEEIKKAMIDVIQQHVQHERRLFRVLVDVMYETCDLDEIWKLLRYAYASHIEKIEKRMEKEKREKWRRYLLSKDPIVYLATEVYESEKGILEELETFYLTKNFPLFKLVLMEIFQLADESFFLKEQDLYREMFVSSTNEQQQKMAHELIKKCKLNHVKPLGRLIFEKLQTYRRKPMLWKYVGEEEKRRFAQWIMKLELKDFFGGVNKNHERFQYWEKFIPKLEDVVVTDERTTLIMYFRDVVIMEVLGTGAVYIYPADVFQRHFQPKIDRMLAERERFVNKAWLKVREVKRTELMDRNLTIPGGWLRHNVGWQWKFDEWLRRELGWEVRRDVLLQKETEDDESSLDAE
>NZ_CP017690.1|WP_008879443.1|634482_635154_-|OmpA-family-protein
MKYRRRTEVNYWMSYADLMSAMLMVFALLLTFVILDYRELLEEKEKKIEQVVSVKSEIIRALTEAFKQSNMTIEIDQQTGAIRFPGSILFESDSAEISPEGKKFLQQFIPKYMGILLQDRFQNEISSIIIEGHTDRNGTYMYNMSLSQRRAYAVLEYIYSKEFPNFKERELSKKYITANGRSFSSPLTDENGKYDPDRSRRVEFLFRLKDDEAIKAIEKLVNE
>NZ_CP017690.1|WP_008879444.1|635150_637097_-|MotA/TolQ/ExbB-proton-channel-family-protein
MYTFFESFFSLINKVGNKGFTDLFLYFQLALFLAMAIWQFVRIQREIAVMNQLKPKLLELNRSANGTAYEIDQAINELFVQVKKSKYKELWERYYNRVSQKNEDERINVEPFFGFDVMHHHMGYRTLMDMGAGIHVSLGVLGTFVGLSVGLSELHINDTEALRSGIGSLLDGMKVAFYTSVWGVLLSLMWTMFDRWISSTLDRNIDWHSERLDFLLSTDDEELFLNRLEKLSRNQADHLKTLLTDALEKAMQPIALSLQQSHGNLQQAFSQLHDQFAQLHEGMETQAKLLESQIELTKNTSADVTSRLVDEITGGTQQSIGRFSEFVQQSQVWQTEMIKTIEVFVSRFAHTEERQAMTLERTEKMFAQFEKMAVELELMKESYQKTSGMMNRLGETFQRLQELTKDQLPVQQEVMRSNQLLAQKYDDLSERFTRFNAQIETQYSQLLEQLVHATSSLSASFQTMANRFDESLRIQKESLHDSQQLLGDVQSAVAALSPLVSELRETFDHVRELKEQLLEMQEAQKQLLPELVQLRTQTKESVEETLRTTKVYMQEMTEQIGMLQENWTTTKEQLTKITEALHLSMKDFAENIDSGLSKTYQHFDETLTKAVQEVSGLVYQFSEVQSDFIDNLEDLVDHFDKWKAGASS
>NZ_CP017690.1|WP_011887243.1|637423_641194_-|AAA-family-ATPase
MFYVSPAKIASYFYHECERNLYFRSLAKERRGELDVPEELFRRPASHENVLRRGVEWEKTVISTYLADEVKMGKQVSDLPLSHCYLDSEETIRELKEPSKRYLYQPTLIVPPRFYERYGLNPGTVRFAACRPDVIECVRGQDGWTFRIIDIKSSDALQFSHRVQTALYALILSFVLEEHGIKGKVDLDETRIWTYGAEQPQTTNIRQLIPYIEHFLSSELTILTEKQADDLFWHLDYRCEWCPFYSYCLDKARQQAHISLVPYLSSYTSRFVREQQLPETIRAFHQFLQREENGSVLKQNATLARQRRRLETQLMAIAKEKVIPHDRVVADMPKWEDIRLIFTAQRDQATGKIAAASLYRVGGIDVFGTGSEMHHFVARCLEECDAVIRKFVDALDRLLQTVHDYNKTREWQAQKSVQAYVVDNYEWDNLQHMLSELLLDREYQEKAVRLLFYFHSGVLSSAHQHPKEMVPLPVVVLTTVASQLFALPVHVAYRLEDLSAYIAAYSDRPFTYRANERFSFRLTNAMKMDVLHDAWQTGDEEKRKEVEGELRRRLWAAHSIIRGIRAWAARIQPSPLAVWPEKFRFPDSAHYRDPLISKLAFMARYEALLNYLDVRQRRSLPLADRLETGVTLHITYLGAKRFRLNNRHALEAIDQKANWLLTECDEEGEKAQQTFPDMKYAGDRSAPRWANLYFARIRTIDDDGKTAELELELPRLLDRFPLVKGENYLLSLRYADLTTVRVLRALQALDQENHRILDLIRDPIRYRKTFRPKWEADEVKALLRESRLTKSQRQAFLHLLRYTLTLVWGPPGTGKTHFIAAALRLLMAIYEKRGRRLAILISGFTHAAIENCLNKIKELAPQGKVSIAKLGAVQTENAKGIIELADGEVWEWLDSGRHCVLGATLYGIQRAHEKGLLAGGFDVVVLDEASQIRVADSLLALRHVKKAGRLLIVGDHFQLPPIIQGAYKTVEGEPPLFESIFRLLFDADVEKRLTCQLTDNFRMNETLCRYPAEQIYGRDYTAFNRRIAEQTLTLAAAPTADEWVEAAIDPDYPLVVCTYDGVYGAQENEAEARWVASVTKTLRERLLDGDGKRYHDTPDGDKAFWRNGLFIISPHRAQIRAIRRALEREGLRPPFFVDTVDKMQGQEAEAAIISYGVADPELAAMEGEFIYSLNRLNVSLTRARKKTILFLSRHLLSPSLHVLGNDDYREGVNFMIGLEHYASRHGEAQTFVVDGAVLHMYRVGCRVFDQVASRHH
>NZ_CP017690.1|WP_008879446.1|641488_642448_-|siderophore-ABC-transporter-substrate-binding-protein
MKKWWLSVVAALLLVVLAACGNSENTSSNTSNDNNEKKAAQVEEITVKHELGEVKVKKNPEKVVVFDFGVLDTLDRLGTNVTGLPQMNVPSYLEKYKSGDYENVGSLQEPDFEKLSEIQPDVIFISGRQAKLYDKFSEIAPTVYMAVDTKNYLDSFSNNMKLLGQIFDKEDEVEAELENIQKQIDSVKAKAGDKKALIILTTGGKVSAYGKGSRFGLIHDVLGVQAVDPNLKADTPHGQNVSFEYIAEQNPDYLFVIDRDAVVEGKPTAKQTIENALVKKTKAYQNGHIVYLDPNYWYLSGGGLTSVSEMIKQVEQGLE
>NZ_CP017690.1|WP_008879447.1|642703_643459_-|ABC-transporter-ATP-binding-protein
MVEVKQVSKRYGGKKVVDEVSLSIPRRQLTSLIGPNGAGKSTLLSIMSRLIPKDSGEVWIDGKEISRYRTEELAKKISILKQSNHIAARLTVKELVSFGRFPYSRGRLTRQDNEYVREAIHYMELDDLQHRYLDELSGGQRQRAYIAMVLAQDTDYIFLDEPLNNLDMKHSVQMMKVLRNLVDQLDKTIVIVMHDINFASCYSDYIVALKDGKVVSEGDVSTMMRSQVLRGIYDMDVHIQTIENRRICVYF
>NZ_CP017690.1|WP_008879448.1|643452_644403_-|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MSNRMKTAALVVLALAFIALFLFTELRGNIEYVLRSRGEKVTAMVLVGWAGAISTVLFQTITNNRILTPSIIGLDSVYMLIQTAVVFLFGSTTLTMMNDTVHFLLSAGGMIGFSVFLYSFLFRREGQTVYFILLVGMILGTFFQSVTSFMQYLIDPNEFSIIQDRMFASFNNMKTELLWPAGIVIVVAIWYTYRHLHELDVLSLGKDHAINLGVSYETVVRRMLMVIAVLVSVSTALVGPIMFFGLIVANVAYAFFQTYEHRYLLVGAALFGIIALVSGQFVVERVFTFSTTLSVIINMVGGVYFLYLLLKERKAW
>NZ_CP017690.1|WP_011887242.1|644395_645352_-|ABC-transporter-permease
MRTMKKWVLLLFGLSLLSLFVGVHDLSPRALWEGDRDAWEIFLISRLPRLVSIIIAGASVSICGLIMQQLSQNKFVSPTTAGTMDWARLGLLVSMILFASASPIVKAAIAVLFAFTGTLLFMTVLDRVKYKDSVFIPLVGLMFGNIIGSVTTFLAYKYDLIQSVSAWLQGDFSVMMQGRYEMLYISVPLMAIAYAYANRFTIAGMGEEMATNLGLRYRSIVYTGLIIVAVTSSIEVLTVGSLPFLGLIVPNIVTMYYGDHLRKVLPVTALAGALFVLVCDLFGRIVIYPYEIPIGLTVGVIGSGVFLYLLIRRTKQYV
>NZ_CP017690.1|WP_172437874.1|646227_647895_+|IS1634-family-transposase
MYIRRVTRKNKDGTTVAYLQLAHNEWDPKAKYAKAKVIYSFGREDEVDRAVLERLAKSISRFLSPEQAWEIETLTGEVSDDFQFQSSKRLGGAWLLDQLWRQLGLGEILHSLFASRHHQIPLERLIFAMVANRALHPSSKLAMKEWVEKDVHIPHLPQVASHQLYRAMDELLAVQPELERQVFHAVADLLNLEVDLIYFDTTSSYFEVDPSETPEGESLRKQGFSKDKRPDLVQIVIGLAVTREGVPIRAWVWPGNTMDMTVIKQVKQDLIGWKLGRVISVMDRGFSSEENLRILQQAGGHYIVGEKMRSGKAAVEEALNRRGRYQQVRENLHIKEIIVGDGEARQRYVLVYNPSEAERQRKERETLLESLKEELEGLRQLPNEAHHKATCRLRSHPSYGKYLRQLKDGTLRIDKQAVREAEKYDGKYLIRTSDDTLSAEDVALGYKQLVDIEQAFRTLKSTLELRPMYHRLEDRIRAHVLLSWLALLLVRIVEIRTHESWPKVRDECERLMLGHFSSKNGDLYQRTELTAKQALFLAALGLEPPPKILGIHPRT

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Crispr_ID: NZ_CP017690_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017690_3

1716103-1717580

Orphan

Consensus_repeat	Method
GTTTTTATCGTACCTATAAGGGATTGAAAC	PILER-CR
GTTTCAATCCCTTATAGGTACGATAAAAAC	CRISPRCasFinder
GTTTCAATCCCTTATAGGTACGATAAAAAC	CRT

22 spacers

The CRISPR arrays of NZ_CP017690_3

>merge|NZ_CP017690|3|1716103-1717580|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCCTTATAGGTACGATAAAAACGGTGTCGGCGGTTGCTTCCGGGCTTGGCATGTCGTTGTTTCAATCCCTTATAGGTACGATAAAAACTCGTTCCGGCATTGGTTCATCATAGACGCGGATTTGTTTCAATCCCTTATAGGTACGATAAAAACACTCCTCTCTCTCCTTTTTAATCGCATAGTAAGAAGGTTTCAATCCCTTATAGGTACGATAAAAACGCGTCATCCTTCCCGACGAGTTCGCTCGCTGAATAGTTTCAATCCCTTATAGGTACGATAAAAACATGTTCGCACTACTTTTGGAAATGTAGTGGACTATGGTTTCAATCCCTTATAGGTACGATAAAAACGAGTGATTATCCCGGCGAATGCGTATTTCATGATTCAGTTTCAATCCCTTATAGGTACGATAAAAACCCAATCCAATATAGGAGTCATGTCCCCTTATGTTTCGTTTCAATCCCTTATAGGTACGATAAAAACGCTCTTTGCGCTTCGCGTTCATTATCCCTGTGACGTTTCAATCCCTTATAGGTACGATAAAAACCAATTGCAAAACGTCTTTACGATTGACGCGGATAGTTTCAATCCCTTATAGGTACGATAAAAACAAGGGTATCGCCGTTAAATATCGCAAAATCAAAAGGGTTTCAATCCCTTATAGGTACGATAAAAACAAATGTCAAAGCCGCTTCGCACACTTCTTGTAGCTCTTGTTTCAATCCCTTATAGGTACGATAAAAACCGAAAAGCGGGATACAGTGCAAGGGGAAATACGACGTTTCAATCCCTTATAGGTACGATAAAAACGCATTGGTTGAAGCGAGTGTTTTTCGATGAGGAAAGTTTCAATCCCTTATAGGTACGATAAAAACTTTAGAGCGTATTTTCGGTGTGAAATCGGTTGTCTAGTTTCAATCCCTTATAGGTACGATAAAAACCGGTTTATTGTTGAAAACATCGAGATTTGAAAGCTGTTTCAATCCCTTATAGGTACGATAAAAACGCATTGTTGGCGGCATCGTTCGCATTAGTAGCCGCGTTTCAATCCCTTATAGGTACGATAAAAACGATAAAATAAACCTTTCTTTTCCCTTCTTTCCAAACTTGTTTCAATCCCTTATAGGTACGATAAAAACGAAGATATGGACTATGAGGAAGCGTTAGAACTTTAGTTTCAATCCCTTATAGGTACGATAAAAACATGCTGACATTCTCGAACTCATTTGCCCAGTAGAAGTTTCAATCCCTTATAGGTACGATAAAAACCGATGTATGTCCACACATCCCTACCGGACCATGTAGGTTTCAATCCCTTATAGGTACGATAAAAACGTCCGCGAATACCGCTTGCTTCCTTCGCTATGTTTCGGTTTCAATCCCTTATAGGTACGATAAAAACGCGCTCATACTTTTCGAATGGCGACACGTCAAACGGAAGTTTCAATCCCTTATAGGTACGATAAAAAC

>NZ_CP017690|3|2|1716103-1717580|PILER-CR
GTTTCAATCCCTTATAGGTACGATAAAAAC	GGTGTCGGCGGTTGCTTCCGGGCTTGGCATGTCGTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	TCGTTCCGGCATTGGTTCATCATAGACGCGGATTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	ACTCCTCTCTCTCCTTTTTAATCGCATAGTAAGAAG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCGTCATCCTTCCCGACGAGTTCGCTCGCTGAATA
GTTTCAATCCCTTATAGGTACGATAAAAAC	ATGTTCGCACTACTTTTGGAAATGTAGTGGACTATG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GAGTGATTATCCCGGCGAATGCGTATTTCATGATTCA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CCAATCCAATATAGGAGTCATGTCCCCTTATGTTTC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCTCTTTGCGCTTCGCGTTCATTATCCCTGTGAC
GTTTCAATCCCTTATAGGTACGATAAAAAC	CAATTGCAAAACGTCTTTACGATTGACGCGGATA
GTTTCAATCCCTTATAGGTACGATAAAAAC	AAGGGTATCGCCGTTAAATATCGCAAAATCAAAAGG
GTTTCAATCCCTTATAGGTACGATAAAAAC	AAATGTCAAAGCCGCTTCGCACACTTCTTGTAGCTCTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGAAAAGCGGGATACAGTGCAAGGGGAAATACGAC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCATTGGTTGAAGCGAGTGTTTTTCGATGAGGAAA
GTTTCAATCCCTTATAGGTACGATAAAAAC	TTTAGAGCGTATTTTCGGTGTGAAATCGGTTGTCTA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGGTTTATTGTTGAAAACATCGAGATTTGAAAGCT
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCATTGTTGGCGGCATCGTTCGCATTAGTAGCCGC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GATAAAATAAACCTTTCTTTTCCCTTCTTTCCAAACTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	GAAGATATGGACTATGAGGAAGCGTTAGAACTTTA
GTTTCAATCCCTTATAGGTACGATAAAAAC	ATGCTGACATTCTCGAACTCATTTGCCCAGTAGAA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGATGTATGTCCACACATCCCTACCGGACCATGTAG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GTCCGCGAATACCGCTTGCTTCCTTCGCTATGTTTCG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCGCTCATACTTTTCGAATGGCGACACGTCAAACGGAA
GTTTCAATCCCTTATAGGTACGATAAAAAC

>NZ_CP017690|3|3|1716103-1717580|CRISPRCasFinder
GTTTCAATCCCTTATAGGTACGATAAAAAC	GGTGTCGGCGGTTGCTTCCGGGCTTGGCATGTCGTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	TCGTTCCGGCATTGGTTCATCATAGACGCGGATTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	ACTCCTCTCTCTCCTTTTTAATCGCATAGTAAGAAG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCGTCATCCTTCCCGACGAGTTCGCTCGCTGAATA
GTTTCAATCCCTTATAGGTACGATAAAAAC	ATGTTCGCACTACTTTTGGAAATGTAGTGGACTATG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GAGTGATTATCCCGGCGAATGCGTATTTCATGATTCA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CCAATCCAATATAGGAGTCATGTCCCCTTATGTTTC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCTCTTTGCGCTTCGCGTTCATTATCCCTGTGAC
GTTTCAATCCCTTATAGGTACGATAAAAAC	CAATTGCAAAACGTCTTTACGATTGACGCGGATA
GTTTCAATCCCTTATAGGTACGATAAAAAC	AAGGGTATCGCCGTTAAATATCGCAAAATCAAAAGG
GTTTCAATCCCTTATAGGTACGATAAAAAC	AAATGTCAAAGCCGCTTCGCACACTTCTTGTAGCTCTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGAAAAGCGGGATACAGTGCAAGGGGAAATACGAC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCATTGGTTGAAGCGAGTGTTTTTCGATGAGGAAA
GTTTCAATCCCTTATAGGTACGATAAAAAC	TTTAGAGCGTATTTTCGGTGTGAAATCGGTTGTCTA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGGTTTATTGTTGAAAACATCGAGATTTGAAAGCT
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCATTGTTGGCGGCATCGTTCGCATTAGTAGCCGC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GATAAAATAAACCTTTCTTTTCCCTTCTTTCCAAACTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	GAAGATATGGACTATGAGGAAGCGTTAGAACTTTA
GTTTCAATCCCTTATAGGTACGATAAAAAC	ATGCTGACATTCTCGAACTCATTTGCCCAGTAGAA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGATGTATGTCCACACATCCCTACCGGACCATGTAG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GTCCGCGAATACCGCTTGCTTCCTTCGCTATGTTTCG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCGCTCATACTTTTCGAATGGCGACACGTCAAACGGAA
GTTTCAATCCCTTATAGGTACGATAAAAAC

>NZ_CP017690|3|2|1716103-1717580|CRT
GTTTCAATCCCTTATAGGTACGATAAAAAC	GGTGTCGGCGGTTGCTTCCGGGCTTGGCATGTCGTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	TCGTTCCGGCATTGGTTCATCATAGACGCGGATTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	ACTCCTCTCTCTCCTTTTTAATCGCATAGTAAGAAG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCGTCATCCTTCCCGACGAGTTCGCTCGCTGAATA
GTTTCAATCCCTTATAGGTACGATAAAAAC	ATGTTCGCACTACTTTTGGAAATGTAGTGGACTATG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GAGTGATTATCCCGGCGAATGCGTATTTCATGATTCA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CCAATCCAATATAGGAGTCATGTCCCCTTATGTTTC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCTCTTTGCGCTTCGCGTTCATTATCCCTGTGAC
GTTTCAATCCCTTATAGGTACGATAAAAAC	CAATTGCAAAACGTCTTTACGATTGACGCGGATA
GTTTCAATCCCTTATAGGTACGATAAAAAC	AAGGGTATCGCCGTTAAATATCGCAAAATCAAAAGG
GTTTCAATCCCTTATAGGTACGATAAAAAC	AAATGTCAAAGCCGCTTCGCACACTTCTTGTAGCTCTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGAAAAGCGGGATACAGTGCAAGGGGAAATACGAC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCATTGGTTGAAGCGAGTGTTTTTCGATGAGGAAA
GTTTCAATCCCTTATAGGTACGATAAAAAC	TTTAGAGCGTATTTTCGGTGTGAAATCGGTTGTCTA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGGTTTATTGTTGAAAACATCGAGATTTGAAAGCT
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCATTGTTGGCGGCATCGTTCGCATTAGTAGCCGC
GTTTCAATCCCTTATAGGTACGATAAAAAC	GATAAAATAAACCTTTCTTTTCCCTTCTTTCCAAACTT
GTTTCAATCCCTTATAGGTACGATAAAAAC	GAAGATATGGACTATGAGGAAGCGTTAGAACTTTA
GTTTCAATCCCTTATAGGTACGATAAAAAC	ATGCTGACATTCTCGAACTCATTTGCCCAGTAGAA
GTTTCAATCCCTTATAGGTACGATAAAAAC	CGATGTATGTCCACACATCCCTACCGGACCATGTAG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GTCCGCGAATACCGCTTGCTTCCTTCGCTATGTTTCG
GTTTCAATCCCTTATAGGTACGATAAAAAC	GCGCTCATACTTTTCGAATGGCGACACGTCAAACGGAA
GTTTCAATCCCTTATAGGTACGATAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017690.1\|WP_011886718.1\|1721142_1721916_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP017690.1\|WP_099233040.1\|1713969_1714530_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|285278
NZ_CP017690.1\|WP_081157607.1\|1726828_1728349_-\|flotillin-family-protein	unknown	unknown	gnl\|CDD\|225177
NZ_CP017690.1\|WP_011886722.1\|1710012_1710603_-\|GrpB-family-protein	unknown	unknown	gnl\|CDD\|377252
NZ_CP017690.1\|WP_011886726.1\|1705654_1705834_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_099233038.1\|1713173_1713977_-\|DUF4097-family-beta-strand-repeat-protein	unknown	unknown	gnl\|CDD\|372574
NZ_CP017690.1\|WP_099233042.1\|1718915_1719272_-\|YxeA-family-protein	unknown	unknown	gnl\|CDD\|227613
NZ_CP017690.1\|WP_008881400.1\|1714522_1714846_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP017690.1\|WP_008881410.1\|1725764_1726685_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
NZ_CP017690.1\|WP_029761506.1\|1706028_1707498_-\|alanine:cation-symporter-family-protein	unknown	unknown	gnl\|CDD\|376500
NZ_CP017690.1\|WP_099233036.1\|1710722_1711520_-\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|376187
NZ_CP017690.1\|WP_008881404.1\|1718164_1718515_-\|DUF2200-domain-containing-protein	unknown	unknown	gnl\|CDD\|337575
NZ_CP017690.1\|WP_087959841.1\|1708917_1709403_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_015374614.1\|1711529_1712663_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP017690.1\|WP_087959836.1\|1724307_1725690_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|129571
NZ_CP017690.1\|WP_008881412.1\|1728370_1728907_-\|NfeD-family-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_011886717.1\|1722253_1723639_+\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP017690.1\|WP_060475550.1\|1729724_1731443_+\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320688
NZ_CP017690.1\|WP_008881301.1\|1703926_1705159_+\|serine/threonine-transporter-SstT	unknown	unknown	gnl\|CDD\|184190
NZ_CP017690.1\|WP_011886719.1\|1719296_1721168_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899

Protein	Function_ID	Function_description	E-value
NZ_CP017690.1\|WP_011886718.1\|1721142_1721916_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	5.70405e-110
NZ_CP017690.1\|WP_099233040.1\|1713969_1714530_-\|DUF1700-domain-containing-protein	gnl\|CDD\|285278	pfam08006, DUF1700, Protein of unknown function (DUF1700). This family contains many hypothetical bacterial proteins and putative membrane proteins.	2.09138e-55
NZ_CP017690.1\|WP_081157607.1\|1726828_1728349_-\|flotillin-family-protein	gnl\|CDD\|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	9.68637e-109
NZ_CP017690.1\|WP_011886722.1\|1710012_1710603_-\|GrpB-family-protein	gnl\|CDD\|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	1.41836e-77
NZ_CP017690.1\|WP_099233038.1\|1713173_1713977_-\|DUF4097-family-beta-strand-repeat-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	3.14137e-14
NZ_CP017690.1\|WP_099233042.1\|1718915_1719272_-\|YxeA-family-protein	gnl\|CDD\|227613	COG5294, COG5294, Uncharacterized protein conserved in bacteria [Function unknown].	6.2207e-25
NZ_CP017690.1\|WP_008881400.1\|1714522_1714846_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.12082e-26
NZ_CP017690.1\|WP_008881410.1\|1725764_1726685_-\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
NZ_CP017690.1\|WP_029761506.1\|1706028_1707498_-\|alanine:cation-symporter-family-protein	gnl\|CDD\|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	0
NZ_CP017690.1\|WP_099233036.1\|1710722_1711520_-\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	1.61755e-07
NZ_CP017690.1\|WP_008881404.1\|1718164_1718515_-\|DUF2200-domain-containing-protein	gnl\|CDD\|337575	pfam09966, DUF2200, Uncharacterized protein conserved in bacteria (DUF2200). This domain, found in various hypothetical bacterial proteins, has no known function.	1.28653e-79
NZ_CP017690.1\|WP_015374614.1\|1711529_1712663_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.13552e-25
NZ_CP017690.1\|WP_087959836.1\|1724307_1725690_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|129571	TIGR00479, 23S_rRNA_uracil1939-C5-methyltransferase_RlmD, 23S rRNA (uracil-5-)-methyltransferase RumA. This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification].	0
NZ_CP017690.1\|WP_011886717.1\|1722253_1723639_+\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP017690.1\|WP_060475550.1\|1729724_1731443_+\|M48-family-metalloprotease	gnl\|CDD\|320688	cd07329, M56_like, Peptidase M56-like, integral membrane metallopeptidase in bacteria. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain beta-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	6.37771e-35
NZ_CP017690.1\|WP_008881301.1\|1703926_1705159_+\|serine/threonine-transporter-SstT	gnl\|CDD\|184190	PRK13628, PRK13628, serine/threonine transporter SstT; Provisional.	0
NZ_CP017690.1\|WP_011886719.1\|1719296_1721168_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	2.25456e-06

>NZ_CP017690.1|WP_008881400.1|1714522_1714846_-|PadR-family-transcriptional-regulator
MNTQFKKGVLELCVLALLNKQDRYGYEIVQKISEQMVISEGSVYPLLRRLKKEDYLTTYLQESNEGPPRKYYKLTEKGRNHLRNLHEEWMQFSEGVNQIIKDGGLHE
>NZ_CP017690.1|WP_099233040.1|1713969_1714530_-|DUF1700-domain-containing-protein
MNKQQFLTALEKELKKLPHEEREEIIQDFEEHFYIGMANGKSEEEISQSLGSPKQIAKEIAAVSRIEKIETSATAGNVLRAVWAVIGLGFFNFVTVFGPFLALLAVVFVGWFIGVAFIASPLILLVSAINHPGMFDLFSLFFSIMLCGSGWFIVRGMLYVTKVLTDLLVRYLRYNVSLVKGGLKHD
>NZ_CP017690.1|WP_099233038.1|1713173_1713977_-|DUF4097-family-beta-strand-repeat-protein
MINTRHISFLALILLVVGAIGSFITFKPASKPFSVSEERILTDKTITDIEIRANDENVNIFSTKDSKTKVQLTGTSVEKMDHYFSVEVEDGTLLIKLKDDKPFFDFFHFRGTSLTLDVYLSEKVYESLHVDMNNGEIQAEKLRINNIEAKLANGYLEMKDIVATMLKADSDNGEIHLENIEGEIYGNVNNGQIYLKTNHLDRSLTLESDNGDIEIKTDQKPTNAVLDIKTKNGEVTVFGNSNWDTVIGNGENQIKLTTNNGDIRIVK
>NZ_CP017690.1|WP_015374614.1|1711529_1712663_-|IS4-family-transposase
MNKHTTLPNLMQKLVSDEEIQLIAEAVGYRDSSRTFTLRELIHFFLLAAMHQWKSFRHGADVGPLYGLPRFHYSTVSKKAKEVPYDIMKRLLALIISKCNRQTRRSLRFPKPLRVVDSTTVTVGKNRLPWAPYHGERAGVKLHVAYSPESSLPADVVETIGLRHDGPVGEQLTNAQQVLVEDRAYFKIERLDRFVEQHQLFVIRMKDNIELHQKKSLKRLSSTSSSVQADFTCQLGTKQCRSTKRHRVVIFRDANGRDIRVVTNLFHASAETIADMYQQRWTVEVFFRWVKQYLNVPTLFGTTENAVYNQLFAAFIAYVLLRWLYDQTKKQTNVSLSFISFVRRFFSGQLPLDWKSGMAAALFEYAQIYGRRMSNFG
>NZ_CP017690.1|WP_099233036.1|1710722_1711520_-|nucleotidyltransferase-domain-containing-protein
MSCLPFIEGVVLGGSRARGTHEEDSDIDIGIYYNAELFDLNAMNQVAAELDDERRSNLVFPPGAWGKWVNGGGWLVINGYHVDFILRDIKRVEQIIKETEQGMVTADYQTGHPHGYISAMYRGELAISKILYAKDETFCQLKKRAETYPAALRKSLIDFFMFEAEFSLLFVKKNVKANDKYYIVGHVFRMISCLNQVIFACNHAYCINEKKAIKLIETFEHKPENYAQKVNRIFELLGSSLMECCDMTEKLYNEVKQLVSEINHF
>NZ_CP017690.1|WP_011886722.1|1710012_1710603_-|GrpB-family-protein
MMRSENRFTPRSDEELQKLTVGELKPHNAPITLVEYDPRWPELFEREAKRIRSVLGSKALQIEHVGSTSVPGLCAKPIIDMLLVVEDSADEPSYVPALEAAGYRLRIREPEWFEHRLFKGPDTDINLHVFSKGTSEIDKMLRFRDWLRSNESDRDKYAQVKRSLAKNKWRHVQHYADAKTSIVQEILARTNDSNAK
>NZ_CP017690.1|WP_087959841.1|1708917_1709403_-|hypothetical-protein
MIKKGKRGKNYSVSDHIFAITVVSFMCLAIISFPFLLFYAVMHLISLTTDVRIHSLGTFSSLKIILTFFITTVVTTGMVDTIFSIILKRSKGMFGFLSEALLMLAFFYLYVLVYSLVSDDIVMTDKGRLYVSFFLFLMYVSIHLVYIGAKRLYELITRHAS
>NZ_CP017690.1|WP_029761506.1|1706028_1707498_-|alanine:cation-symporter-family-protein
MIEKFVETVNGLLWSPLLIVFIVFCGLYFSIRTRFLQIRHFKEMVKLVTTGKGSDAGVSSFQALTMSLSGRIGVGNVAGTATGIAYGGPGAVFWMWVITFIGAATAYVESTLAQIYKEEQDGQYRGGPAFYIEKGLGWKWFAIVIAVAILLAMAVLMPGIQANSIADSVYNAFGINKLVTGIIVISILGFTIFGGVKRIARTAEIVVPFMAAGYLLIAIAIIGVNFDKIPEVFALIFKSAFGAEQVFGGIIGSAVMWGVKRGLYANEAGQGTGAHPAAAAEVSHPAKQGLVQAFSIYLDVFLVVTATALMILFTNQYNVINEKTGEPIVVNLEGVEPGAGYTQAAVDTLLPGFGSAFIAIALFFFAFTTMYAYYYIAETNLAYLVRGKNKGIAFLGLKIIFLAATFYGTVKTATTAWAMGDIGLGIMVWLNLIAILLLFKPAYIALKDYEEQLKQGKDPEFNSSKYEIKNATFWENGYKKSEENQKKAL
>NZ_CP017690.1|WP_011886726.1|1705654_1705834_-|hypothetical-protein
MNVTNVSISSVILFLFVVSVILFVYGFVRKRKAVKWMALCFFSASIGLAVFVILLMRYM
>NZ_CP017690.1|WP_008881301.1|1703926_1705159_+|serine/threonine-transporter-SstT
MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFLVISAISRHQSGQKTNIQHILILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNITEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRTAPETTKNVIAHFSDAISQIVTWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQNPYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAVTISVLTLAAVHTLEIEVDLGTALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDIAMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRRKEGKQVAIKA
>NZ_CP017690.1|WP_008881404.1|1718164_1718515_-|DUF2200-domain-containing-protein
MTTHKIYKMSFSKVYPNYIAKAEKKGRTKSEVDEIIRWLTGYTQDELEAQLEKQVDFETFFAEAPQLNPNRVLIKGVICGVRVEEIEDPLMQNIRYLDKLIDELAKGKSMEKILRK
>NZ_CP017690.1|WP_099233042.1|1718915_1719272_-|YxeA-family-protein
MKKIIGMIIALVVVFVGFFTIVPEEDRDHINPFIPKEVIYVQIYEDPAPHGQRYKYTLTGYTEDGEEKEITFTAGKVLKEKAILKVNAKGSFVEKWEEIQPEELPEKVRGKMDSVPSN
>NZ_CP017690.1|WP_011886719.1|1719296_1721168_-|ABC-transporter-permease
MTFPQFAYKNITRNLRAYMAFYLSSSFAVMIFFMFAMFIFHPALETGYMNNIAKKGMKFAEWIIFGFSIFFILYSLSTFLKTRKKEFGILTIHGASPKQLRWLITLENVFIGLASIITGILGGTVLAKFFFIAGAYMVKMEPLQLYFPLEALGITVGVFLLLFILISQFMLFTIHSEEVISLLKGSEKPKKEPKPSILFSVLGILFLGTGFGMSLFAGIDMGSAVVITLCTVIGTYLFYSQLSVWMIQLLKRNKKMYRKGINLLWISDLTYRIKDNARLFFIVSIVSAVAFTATGTLATYKLMFSTAETSYAMEFLSYATNQDEKKQLEFIKEKLEQENIDYQQTIFKAIEARQGPMSYPVLVVSHQDWVKQFPELQAPNIHDGEGIYYGEAKRGGYTIVNGNKTKLLTDDQQMSITLQSIEEPVFYLSDILVVDHNTFRQLEQNHELSTMYGFQFENWKESLEISQEIQSQIVGETFNPNAQYFSKAVRYFETVQLPSLSLFIGLFIAIIFFLAAGSFLYFRLFADLYEERKKYKSLAKIGLSEKEMVKISTIQMAILFFLPFLLAIIETGFALHVLQREGGYFHVFQSGVITILGFLGLQIIYFIIMSHSYNKHLKEYVFR
>NZ_CP017690.1|WP_011886718.1|1721142_1721916_-|ABC-transporter-ATP-binding-protein
MEEVLQVKEINKIYQGKVAFQALTNVSFSVEKGEFIGIMGPSGSGKTTLLNLISTIDKPTSGKVLINGQDPHQLKKERLAEFRRKELGFVFQDFNLLDTLTLEENIMLPLTLENVDPELIEEKVKTISKKLGIDAILTKRTYEVSGGQKQRTAIARAIIHQPKLLLADEPTGNLDSKASKDVMQTLQMINENDQTTMLMVTHDPYAASYCHRVIFIKDGKLYNEIYRGTDQKAFFQQIMDVLSMLGGDRDDFSTVRL
>NZ_CP017690.1|WP_011886717.1|1722253_1723639_+|L-cystine-transporter
MNIYLIIFNIAILLLLIGVLVYMQKKHVSFSKRVFTALGLGIVFGFALQGVYGAGSAIVQQSTQWFDIVGTGYVKLLQMIVMPLVFISIVMAFTKLSVSNHLGKIATLIIGLLLGTTAIAASIGIMSSLGFQLEAMEIPSGEAEQTRGQELEQKYEQIQNLSFPQKIIELLPANPFLDFTGQRSTSTIAVVIFAAFVGIAYLGVARKQPEQAEMFKKIVDALYAIVMRIVTLVLRLTPYGILAIMSRVTATSDINTIAKLGKFVVASYIALFVMFAIHLIILALAGLNPITYVKKVLPVLSFAFTSRSSAATLPLNVKAQTTALGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPTVNIDPTSPSFILTLILVVTISSFGVAGVGGGATFAAILVLSTMNLPVALAGLLISIEPLIDMGRTALNVSGSMTAGVVTSRITKELDVNVYNEETQKLEA
>NZ_CP017690.1|WP_087959836.1|1724307_1725690_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAKQQAPVAKNDYYDVTFTDLTHDGLGVAKVDGFPLFVKNALPGERAKVKVIKVKKGYGYGRLIELYEPSPDRVEPPCPVYRQCGGCQLQHLSYEGQLKAKEKQVKEVLARIGKLEHVTVHPVIGMKNPWRYRNKAQVPVGEREGGLIAGFYKERSHEIIDMDACFIQQEKNDVVVQAVKRIAERYGVRPYDELTHRGVLRHIVARYGAATGEVMVVLVTRTERLPHEQEIVRDIIRDIPDVKSIVQNINPERTNVIFGVKTRVLWGSEFITDRIGDIQFAISARSFYQVNPEQTKVLYDKALEYAELTGTETVIDAYCGIGTISLFLAKKAKHVYGVEIVPEAIEDAKRNAAFNGITNVTFAVGAAEDVIPRWYEEGIRADCLVVDPPRKGCDAALLETIMAMKPPRVVYVSCNPATLARDLRILEDGGYETIEVQPVDMFPHTAHVESVARLALKIRA
>NZ_CP017690.1|WP_008881410.1|1725764_1726685_-|diacylglycerol-kinase
MKRARVIYNPTSGRELFKRHLPDVLVRLEKAGYETSCHATEGPGDATKAARQAAEREFDLVVAAGGDGTINEVVNGIANQPYRPKLGVIPVGTTNDFARAIGVPRSIEGACEVIATGEPVAIDIGSVTNEDQTRYFINIAGGGRLTELTYEVPSKLKTMLGQLAYYLKGIEMLPSIKATEAQIEYDGKLFEGEIMMFLVSLTNSVGGFEKLAPDSSLNDGLFDFIIVKKTNLAEFIRLVTLAARGEHINDPHVIYTKANRVKVRSSMQLNLDGEFGGMLPGEFVNLYRHLEVFMPKEKAAQVRTGP
>NZ_CP017690.1|WP_081157607.1|1726828_1728349_-|flotillin-family-protein
MTVEPWLIVVGVVVLLLIGLIAIFIARYRTVGPDEALIVTGSYLGNKNVHVDESGNKIKIVRGGGTFVVPIFQQAEPLSLLSIKLDVQTPEVYTEQGVPVMADGVALIKVGSSIGEIATAAEQFLGKTRQDMENEAREVLEGHLRSILGSMTVEEIYKNRDKFSQEVQRVASQDLAKMGLVIVSFTIKDVRDKNGYLDALGKPRIAQVKRDADIATAEAEKETRIKRAEADKEARKAELERMTEIAEAEKINQLKLAEFRQEQDIAKARADQAYHLEEAKAKQEVMAQQMQIKIIERQKQIELEEKEILRRERQYDSEVKKKADAERYAIEQKAAAEKAKQIAEADAQKYRVETLAKAEAERIRLDGLAKAEAEKAKGEAEAEIIRLKGLAEAEAKQKIAEAFERYGQAAVLDMIIKMLPEYAKQVASPLSNIEKLTIVDTGSGAGGGANRVTGYATNLMASLQETLKASTGIDVKQLLENIAQGGTPASPVNPPTASGQQTNTNE
>NZ_CP017690.1|WP_008881412.1|1728370_1728907_-|NfeD-family-protein
MFGYPPEVVYGAVLVVSALLTVLYFFFSDVLDGLFDVAAHPLFSPQLVLSFFIVASAVGLLAEWYTDWASHWIIWLSVGVALIVVLLLHFFVFLPLRSAEASLGYTDAELEGSLAKVIVSVPPDGFGEILISRKSGAVAKAAKSMNNEAIPSGEEVIIVRMENGIAVVARHDPYQLSI
>NZ_CP017690.1|WP_060475550.1|1729724_1731443_+|M48-family-metalloprotease
MPDVTISIWTAVVGFFLSFLAYFFKKWCPSLYVYILTAILGIGWIVYVFLDQGFIKTVSIFFIFVFSFFSSPVPERSKVQLQEIIDQLKEQGAREIVLSKNKERLLVDFLFSGLFIVIAVLYFLFGPDSPITLILLYSFVSLVVGLTKRVELFRSLRLFYAEHEEVLYAVSLFETKKYPLEELSEVSVQTRPDVLQLFQLFSLFSPNMDYTTSMGKTWKLSFSGEKVYFTPDPSESMAFLLKEEIHKMEEVEVKPFYHQNNWKRLLGKWYFAATVKGVGAYAALITLFTLMGIGPIVTTIVMVLFWIFNLWISDRVLKIALDMKKIDDPDLLPIIEKVFSRAGLSHVDIYVTESAEYNGFAIGANIGRSLVALTSETLKLPHEAIEGILAHEAIHVKKRDVLMGQLLRFLLIGLVLAGVFLFYKAFQNWLEHAQIFVFLSLWLLIFLLPAFQSLFTQWMEVRADHLGATLLDGGNAQMANSLTILCEYQDRALEKSAGYYVTFEKEQEANKKDKKISSLERDSWFFRFLEFQFMSHPPMYWRVHSLQTTETGWSIGKIKLWWCSRFRESLPN

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Crispr_ID: NZ_CP017690_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017690_4

1753428-1753602

TypeII

Consensus_repeat	Method
TGTATTATACCACAGCGATAATCTCAGGGGAACTATGACTGA	PILER-CR
ATTATACCACAGCGATAATCTCAGGGGAACTATGAC	CRISPRCasFinder

2 spacers

cas2,cas1,cas9,cas6

The CRISPR arrays of NZ_CP017690_4

>merge|NZ_CP017690|4|1753428-1753602|PILER-CR,CRISPRCasFinder
TGTATTATACCACAGCGATAATCTCAGGGGAACTATGACAGAGTTCTTGCGCTGCAAGCGTGACTTAGAATTATACCACAGCGATAATCTCAGGGGAACTATGACTAACTCAGGTGACGGTGATTCTTTTTGTTTTATTATACCACAGCGATAATCTCAGGGGAACTATGACTGA

>NZ_CP017690|4|3|1753428-1753602|PILER-CR
TGTATTATACCACAGCGATAATCTCAGGGGAACTATGACAGA	GTTCTTGCGCTGCAAGCGTGACTT
AGAATTATACCACAGCGATAATCTCAGGGGAACTATGACTAA	CTCAGGTGACGGTGATTCTTTTTGT
TTTATTATACCACAGCGATAATCTCAGGGGAACTATGACTGA

>NZ_CP017690|4|4|1753431-1753599|CRISPRCasFinder
ATTATACCACAGCGATAATCTCAGGGGAACTATGAC	AGAGTTCTTGCGCTGCAAGCGTGACTTAGA
ATTATACCACAGCGATAATCTCAGGGGAACTATGAC	TAACTCAGGTGACGGTGATTCTTTTTGTTTT
ATTATACCACAGCGATAATCTCAGGGGAACTATGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017690.1\|WP_011886706.1\|1753955_1754702_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NZ_CP017690.1\|WP_029761612.1\|1744861_1745515_+\|PspA/IM30-family-protein	unknown	unknown	gnl\|CDD\|224755
NZ_CP017690.1\|WP_099233044.1\|1748925_1752174_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP017690.1\|WP_008881425.1\|1745688_1746927_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP017690.1\|WP_060475547.1\|1740614_1741823_-\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273938
NZ_CP017690.1\|WP_011886699.1\|1761654_1762089_+\|NisI/SpaI-family-lantibiotic-immunity-lipoprotein	unknown	unknown	gnl\|CDD\|375645
NZ_CP017690.1\|WP_008881428.1\|1756550_1757684_+\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213262
NZ_CP017690.1\|WP_029761613.1\|1744380_1744902_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_008881427.1\|1755631_1756534_+\|glycine/betaine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270246
NZ_CP017690.1\|WP_060475545.1\|1762182_1763601_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP017690.1\|WP_029761610.1\|1760811_1761600_+\|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit	unknown	unknown	gnl\|CDD\|163445
NZ_CP017690.1\|WP_172437880.1\|1755199_1755370_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_033025194.1\|1747401_1748538_+\|IS110-like-element-ISGka2-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP017690.1\|WP_008881421.1\|1742185_1742848_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP017690.1\|WP_171355770.1\|1752139_1753018_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP017690.1\|WP_171355769.1\|1753004_1753331_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP017690.1\|WP_011886703.1\|1758073_1758703_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NZ_CP017690.1\|WP_008881431.1\|1759355_1760045_+\|lantibiotic-protection-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|163452
NZ_CP017690.1\|WP_029761614.1\|1742837_1744211_+\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|380161
NZ_CP017690.1\|WP_008881432.1\|1760063_1760810_+\|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit	unknown	unknown	gnl\|CDD\|274754

Protein	Function_ID	Function_description	E-value
NZ_CP017690.1\|WP_011886706.1\|1753955_1754702_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	5.44909e-33
NZ_CP017690.1\|WP_029761612.1\|1744861_1745515_+\|PspA/IM30-family-protein	gnl\|CDD\|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	2.10572e-24
NZ_CP017690.1\|WP_099233044.1\|1748925_1752174_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP017690.1\|WP_008881425.1\|1745688_1746927_+\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.70595e-112
NZ_CP017690.1\|WP_060475547.1\|1740614_1741823_-\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.08491e-93
NZ_CP017690.1\|WP_011886699.1\|1761654_1762089_+\|NisI/SpaI-family-lantibiotic-immunity-lipoprotein	gnl\|CDD\|375645	pfam18218, Spa1_C, Lantibiotic immunity protein Spa1 C-terminal domain. This is the C-terminal domain found in SpaI present in Bacillus subtilis. SpaI is an immunity lipoprotein that protects the Gram-positive bacteria against their own lantibiotics, in this case subtilin. SpaI together with the ABC transporter SpaFEG protects the membrane from subtilin insertion.	2.17556e-40
NZ_CP017690.1\|WP_008881428.1\|1756550_1757684_+\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	7.94542e-164
NZ_CP017690.1\|WP_008881427.1\|1755631_1756534_+\|glycine/betaine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270246	cd13528, PBP2_osmoprotectants, Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold. This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.82169e-141
NZ_CP017690.1\|WP_060475545.1\|1762182_1763601_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	8.82508e-41
NZ_CP017690.1\|WP_029761610.1\|1760811_1761600_+\|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit	gnl\|CDD\|163445	TIGR03733, lanti_perm_MutG, lantibiotic protection ABC transporter permease subunit, MutG family. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family is largely restricted to gallidermin-family lantibiotic cassettes, but also include orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes. In most species, this subunit is paralogous to an adjacent gene modeled separate by TIGR03732, while in some species only one subunit is found.	1.21815e-90
NZ_CP017690.1\|WP_033025194.1\|1747401_1748538_+\|IS110-like-element-ISGka2-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.45792e-30
NZ_CP017690.1\|WP_008881421.1\|1742185_1742848_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.0977e-79
NZ_CP017690.1\|WP_171355770.1\|1752139_1753018_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.7474e-95
NZ_CP017690.1\|WP_171355769.1\|1753004_1753331_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.0612e-43
NZ_CP017690.1\|WP_011886703.1\|1758073_1758703_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.54248e-80
NZ_CP017690.1\|WP_008881431.1\|1759355_1760045_+\|lantibiotic-protection-ABC-transporter-ATP-binding-protein	gnl\|CDD\|163452	TIGR03740, galliderm_ABC, gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.	2.75412e-140
NZ_CP017690.1\|WP_029761614.1\|1742837_1744211_+\|GHKL-domain-containing-protein	gnl\|CDD\|380161	NF033092, HK_WalK, cell wall metabolism sensor histidine kinase WalK. This model describes WalK as found in Staphylococcus aureus (sp\|Q2G2U4.1\|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.	9.9365e-73
NZ_CP017690.1\|WP_008881432.1\|1760063_1760810_+\|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit	gnl\|CDD\|274754	TIGR03732, lanti_perm_MutE, lantibiotic protection ABC transporter permease subunit, MutE/EpiE family. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family is largely restricted to gallidermin-family lantibiotic cassettes, but also include orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes. In most species, this subunit is paralogous to an adjacent gene, modeled separately.	1.04702e-91

>NZ_CP017690.1|WP_171355769.1|1753004_1753331_+|CRISPR-associated-endonuclease-Cas2
MFMSKFMRLLVFFDLPVVTKREKREYRRFRTFLLSEGYDMLQFSVYSRVCHGHEATDKHLARLKQNLPPQGSIRAMVVTEKQYAKMQLLLGEPTVQEKKLTSTQLTLF
>NZ_CP017690.1|WP_171355770.1|1752139_1753018_+|type-II-CRISPR-associated-endonuclease-Cas1
MRKPGKLSVRYNQLVIEQEEKISIPLEDICSIVIEEQAVSVTAVALSKMAEYNIALFTCDQKRLPNGIWQPFQKHSRQVGVLHMQYAYSKPFKKRIWQRIVIQKLINQGKCLEFLNKQGADELYRISKTVDSGDSNNREAYGAKKYFQYLFGNEFTRRSDSVINAALNYGYAIMRGLVARSLVGYGFFPCLGIYHDNELNKFNLADDFMEVLRPLVDLYVAHHVQPDDEFSSSIRADLYNLVNMDILLNEEKLTVVNAVEEMAKSFVTASRSQDPSLLKLPELLPLQLHVYE
>NZ_CP017690.1|WP_099233044.1|1748925_1752174_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKYKIGLDIGITSIGWAVINLDIPRIEDLGVRIFDRAENPKTGESLALPRRLARSARRRLRRRKHRLERIRRLFVREGILTKEELNKLFEKKHEIDVWQLRVEALDRKLNNDELARILLHLAKRRGFRSNRKSERTNKENSTMLKHIEENQSILSSYRTVAEMVVKDQKFSLHKRNKEDNYTNTVARDDLEREIKLIFAKQREYGNIVCTEAFEHEYISIWASQRPFASKDDIEKKVGFCTFEPKEKRAPKATYTFQSFTVWEHINKLRLVSPGGIRALTDDERRLIYKQAFHKNKITFHDVRTLLNLPDDTRFKGLLYDRNTTLKENEKVRFLELGAYHKIRKAIDSVYGKGAAKSFRPIDFDTFGYALTMFKDDTDIRSYLRNEYEQNGKRMENLADKVYDEELIEELLNLSFSKFGHLSLKALRNILPYMEQGEVYSTACERAGYTFTGPKKKQKTVLLPNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARELSQSFDERRKMQKEQEGNRKKNETAIRQLVEYGLTLNPTGLDIVKFKLWSEQNGKCAYSLQPIEIERLLEPGYTEVDHVIPYSRSLDDSYTNKVLVLTKENREKGNRTPAEYLGLGSERWQQFETFVLTNKQFSKKKRDRLLRLHYDENEENEFKNRNLNDTRYISRFLANFIREHLKFADSDDKQKVYTVNGRITAHLRSRWNFNKNREESNLHHAVDAAIVACTTPSDIARVTAFYQRREQNKELSKKTDPQFPQPWPHFADELQARLSKNPKESIKALNLGNYDNEKLESLQPVFVSRMPKRSITGAAHQETLRRYIGIDERSGKIQTVVKKKLSEIQLDKTGHFPMYGKESDPRTYEAIRQRLLEHNNDPKKAFQEPLYKPKKNGELGPIIRTIKIIDTTNQVIPLNDGKTVAYNSNIVRVDVFEKDGKYYCVPIYTIDMMKGILPNKAIEPNKPYSEWKEMTEDYTFRFSLYPNDLIRIEFPREKTIKTAVGEEIKIKDLFAYYQTIDSSNGGLSLVSHDNNFSLRSIGSRTLKRFEKYQVDVLGNIYKVRGEKRVGVASSSHSKAGETIRPL
>NZ_CP017690.1|WP_033025194.1|1747401_1748538_+|IS110-like-element-ISGka2-family-transposase
MDVIYPRCAGLDVHAETIVACALWEEDGHIQKDIQTFSTFSKGLGDLLEWLEEHGVTHVAMESTGVYWKPVFAFLEGYVDLTLANPQRIKNVPGRKTDVSDAEWIAKLLRHGLVEKSFVPPADIRELRDFTRLRKKWVGQLTSEKNRIQKVLESSNVKLGSVLSDLFGVSGKDILARLLEKGYVDKDELDQCLRGRLKKKKQAVYDSLLGTLTEHELRLLRLLWKHVEELEQLIEEVDQHIDRLLEPYREEVELLMTMPGVKKQTAAVIIAEMGTDMSVFETPERAASWTGLSPGNHESAGKRKSTRTTKGNPHLRSALCEAAWSAARSKTHPLSRKFWSLAARCGKKKALIAIARRMLVIIFCMISRKEPFRQPQLI
>NZ_CP017690.1|WP_008881425.1|1745688_1746927_+|MFS-transporter
MDWKRSVRILWLCNFMVSAGMTMVIPFLSLFLWQMGVTEHHALSMWTGLVFSATFLSAAIMAPIWGMFADKYGQRANLIRAGIGMGLLTACMAFAASPMALLVLRFLVGFFSGFITVSFSYLARIVPKDHSGEALGTLQTGSIAGNIIGPLIGGALSDLFGFRPVFLVTGLCILLTLLPVMFWLEKDPVVPQTKKNKASFKEVFEHRPLIILFIATFLVQIAVLGVNSMMTIFVQSLVGNTSNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQEKTLPILLVLSGLFALPQVWTDNIYALYVWRFLQGLVVGGVWPAIQALINVQSPRRIQGRVFGVTASSRFLGNLTGPTAAGAIASLFSIAYIFAFSSLLLIVTGALVGYAHRRSSSVWRKEMKEKLTTWTHRLHSRH
>NZ_CP017690.1|WP_029761612.1|1744861_1745515_+|PspA/IM30-family-protein
MGVFRRIKTIVLAEVNEQIDQWEDPIAMTKQYLRELEQQLEQGRQALAQQWVTEQRYATLIAQAEETVEKRNRQAKLALERNEEAVAKLALGDKLLYEKKLETYKQQYETIKAKTAEIVRRLNQLRERYDELAAKQLELTARVNAAKALKQIDTTLASFSADEALRGFARMEERVIALEAEASAARFGTNAVLSPVPFEEEVERELAKWKEAQSTNA
>NZ_CP017690.1|WP_029761613.1|1744380_1744902_+|hypothetical-protein
MKKLRALALLALIVLAGVSLFHVLTPHEVIVYRRLSVLFDGMHGGFGHHHLIFRVEPRAGWLIPGLLMWFIPLLLVGVGAIWLVAKRSKRWIGWALITLGIAALLPKWVLLGLALAAVYAFGRHQTRKSVAAETWKPTTAPISTDWLDEWEKIVQKEGKTNGCVPPDQNNRSR
>NZ_CP017690.1|WP_029761614.1|1742837_1744211_+|GHKL-domain-containing-protein
MINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAAALFYWITTSEQEQRITRLAEQEANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPTGRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPKHMPGLARDAARDWRVLTAAHPLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEEAYERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLMNDLLTLARADAKHAALELAKQTFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTADPDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSVKDTGIGIPPEDMGRIFDRFYRVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA
>NZ_CP017690.1|WP_008881421.1|1742185_1742848_+|response-regulator-transcription-factor
MKVLLAEDDLHLGELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDGVDICRRLRQNGYTGAILILTAKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRTFVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLLDLLVQNQGQVVPRETILDRVWGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK
>NZ_CP017690.1|WP_060475547.1|1740614_1741823_-|trypsin-like-peptidase-domain-containing-protein
MDMMTFEPTPPPQPKRRGRFVSWLAASVAGAVIGSVATWYVAPKWLNQGNVAQTQLTQTNGKKSETLPLQPTASTNTNMIAAINEVADAVVGVINIQKQADFFSNQVQNTEAGTGSGVIFKKDGNTAYIVTNNHVIEGANEVEVALANGKKVKADIVGADALTDLAVLKIPANGVTKVASFGDSSNVPIGEPVAAIGNPLGLDLSRTVTEGIVSGKRTMPVSTSVGNWEIDVIQTDAAINPGNSGGALINSAGQVIGINSMKIAQTGVEGLGFAIPSENAQPIVEQLMKDGTVKRPYLGVQLVDVADLSADVRNDELKLPSSVTQGAAVTAVEPFSPAAEAGLKSKDVIVAINGDKIDSVSALRKYLYTKTSVDERIKLTIYRDGFETTVSVTLKTKQNNQS
>NZ_CP017690.1|WP_011886706.1|1753955_1754702_-|CRISPR-associated-endoribonuclease-Cas6
MRLTITMNGRQGPVSLPLHYQHLLQGLLYRSLESKQLATFLHEIGFRHEKRSFKLFTFSRLFGRHEVDRVKKTIRFLDEFQWHIDTILPELTEQLGQQLLLRREIWLYDQPVEVKSVKMDKVEIRQSTIEVAMLSPLTVYSTYETIDRRKKTHFFGPDDEVFPHLIELNFRHKYQAYYGVPPVERLSIQPVHVHQRHRVVTLFKDMYITGWLGHYRLSSSPEQLTFLYHVGLGSRNSQGFGMFCLTGK
>NZ_CP017690.1|WP_172437880.1|1755199_1755370_-|hypothetical-protein
MLPPPRQFTGLPSGLAKLAFVIAESLQPMAKKMKQRQTAGGQEVALGRLLFGCFET
>NZ_CP017690.1|WP_008881427.1|1755631_1756534_+|glycine/betaine-ABC-transporter-substrate-binding-protein
MLRKWFMSLLAVGLVLGLAACSGKSDAKGKIVITGKKFTEQMILTHVLAEYVKANTDLDVEVKESLGGAFMLQQAIENGDIDMYVEYTGTGYLNILKQPYDPTKTPEQIYNETKKLYKEKYNIAWLKSLGFNNTYALAMRRDLAEKLGVKTYSDLVNHSSSLTFGSDAEFFERSDGYDGLVDTYGFHFKKTVNIDPDLQYEAAKNGKIDVITAYTTDARIKKYDLVVLKDDKQYFPPYYAVPIIRQEVLDANPGLEEKLNQLANILTDEKMMELNGEVNLEGKQPRKVAIDFLKSEGLID
>NZ_CP017690.1|WP_008881428.1|1756550_1757684_+|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MIRFENVTKQYEDGFVALKNINLEIRKGELVALIGPSGCGKTTTMRMINRLIEPTSGKVYIDGQDISELDPVELRRNIGYVIQQIGLFPHMTIAENIALVPKLKKWEKHAYEKRVDELLELVGLDPATFKHRYPSELSGGQQQRVGVVRALAAEPDIILMDEPFSALDPISREQLQDDIIRLQEEIHKTIVFVTHDMDEAIKIADRIALMKDGEIVQFATPDQMLRRPANSFVREFIGEDRLQMRTRQTAVPTAEDLMSDDVATISPRRGLAEAFRLMKARKVDSLVVVDKKHSFLGIVTLKQIEQRYNEEHLLVADIADYDVTTLQKEAGVTDVAALFQDSDVRIIPVLDGDRLVGGITRSSMMRALAEWTFQQHA
>NZ_CP017690.1|WP_011886703.1|1758073_1758703_+|ABC-transporter-permease
MELLQTFIERQEEIWIAFQEHVLLSAIAMGIAIAVAVPLGVVLTRYRKLAEPIIGIAAIIQTIPSLALLGFMLPIFGIGKLPAIIALTLYALLPILRNTYTGILGVDPALVDAGRGMGMTSRQILWMVELPLSLPVIMAGVRTATVLTIGVAALATFIGAGGLGDLIDRGLRIADKNLILAGAIPAAILAIVFDWLLRKVEKKVTPKGL
>NZ_CP017690.1|WP_008881431.1|1759355_1760045_+|lantibiotic-protection-ABC-transporter-ATP-binding-protein
MGEYMLETHHVSKAFGKQLVVDDVSIKVKKQTVYGLLGPNGAGKSTLLKMLTGLLRPTKGEIMINGHPWSRKDLKDIGVLIESPALYGNLTAHENLLVHAKLLHLPESRIQEVLNIVGLENTGKKKASQFSLGMKQRLGIAKALLNHPKLLILDEPTNGLDPLGIQDLRKLIQSFTENGITVILSSHILSEVKQLADYIGIIQNGKLRYEGKIDESQDLEKLFVDVVNE
>NZ_CP017690.1|WP_008881432.1|1760063_1760810_+|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit
MLNMFESERLKYKRTFAKKLVFIAPLFFVLYAIITMPTINSTHNYFEYAVFNWWPLIFVPIGTALIASLSTVREKKSGNDKVLRCHDISIVRLWWSKITVIAYYMLLSTIELIILLVLLKWLFPNSLSSATVAVFASLVIWLTSLAYIPIGLFVAERFGMVVSIIVSVIGLALGVVMAAQPYWLFIPWSWGMRMMCPIVGVHPNGVPLEKGSPLLDPSVIPIGLAIALVMFLLLSFLTAVWFARKEVY
>NZ_CP017690.1|WP_029761610.1|1760811_1761600_+|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit
MWFLRLLSSEWIKTKRTAIRMMVIITPIIYSLFMVWYFSHYRTSTFWQMKIYQGFFEVMAVSLPIIISLLTGLMSYQEEKAGSFMNILTGPVSKVQWYVGKLTLLIFIACADILLATILMLVGMKYVLKVAHIHYQLFLQGAMLSIVGSLILFSLHLFISFAFGMGASIAVGSGGFLISALIGATSLGDHVWSYIPWAWAVRLSQFPILMMPEVKQALGAQLLNSFSLSLWEGIAYALLSFIIVTIIGSIWFHRWEGNQPHE
>NZ_CP017690.1|WP_011886699.1|1761654_1762089_+|NisI/SpaI-family-lantibiotic-immunity-lipoprotein
MKNSILLLMLIGILFIGGCSLVSDLKKTATQNMEIDRKLPKYELNKENLQEIHYQGRTYMIQAAKVDRNQLNKPIGKVAETITINEHHQILSKKELRKIEVIPDQTDEKRTHLNFGWVYSIKGVNPDEEVAVTVNHQFLIAKRK
>NZ_CP017690.1|WP_060475545.1|1762182_1763601_-|HAMP-domain-containing-histidine-kinase
MKKNKTIKRDFYLLVVKVVLATAISSAVTYLCLIYLIITLATNDVVKPTNYFVKDLDLIEKKVKENEEAIFKGRLIPIHRYSEKIQGEVVDISGKHLYGDREIIDDQVDISQSINREIVKGSYVYRFIPLKHDNAIQAVYVLKAPFGFIINNQNRFEAVLIYAVMFISPLIFFIVYLIFFTSRLYKSLFHNVKLLLQASDHIASGNFDFQVSGLKRKEFIKIQDSFNTMISALKEMVERLAKTDDERKMMVSSIAHDIRTPLTVIQGQIDLIQDLRKLDHFDVTPHLEIIRKNCGKMTMLTDNLSLLYKVENDHFSLNGKEVDVRQILEEKKLEISTMVYHQKSINICFDVNLQKSRYILDEAMLMRVLDNILYNSLRFTKSGEIKLEVYDEKEGNEWKIYFRCSDTGTGFKENDTSLLFQPFYQDKQYKNHVGLGLYIAKRIVNHHGGEIWAYNNEKGGATVEFYIKELSD

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Crispr_ID: NZ_CP017690_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017690_5

3575931-3576117

TypeIII-B?,TypeIII-A

Consensus_repeat	Method
GTTGAAAGAGATAGGCCTCGTTTAGAGGATTGAAACAC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP017690_5

>merge|NZ_CP017690|5|3575931-3576117|CRISPRCasFinder
GTTGAAAGAGATAGGCCTCGTTTAGAGGATTGAAACACGTTGAATGACGTTTCAGCGCCATTCGAGCCTCTGACGTTGAAAGAGATAGGCCTCGTTTAGAGGATTGAAACACCACCAAAAATGCGCCTGGTTTTAATACTCTTGCTTTTGTTGAAAGAGAAAGGCCTCGCTAGGGGATTGGAACATC

>NZ_CP017690|5|5|3575931-3576117|CRISPRCasFinder
GTTGAAAGAGATAGGCCTCGTTTAGAGGATTGAAACAC	GTTGAATGACGTTTCAGCGCCATTCGAGCCTCTGAC
GTTGAAAGAGATAGGCCTCGTTTAGAGGATTGAAACAC	CACCAAAAATGCGCCTGGTTTTAATACTCTTGCTTTT
GTTGAAAGAGAAAGGCCTCGCTAGGGGATTGGAACATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017690.1\|WP_008880548.1\|3569655_3570225_+\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP017690.1\|WP_008880546.1\|3568957_3569323_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP017690.1\|WP_099233504.1\|3574840_3575689_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NZ_CP017690.1\|WP_008880566.1\|3581663_3582383_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226663
NZ_CP017690.1\|WP_029761786.1\|3580919_3581663_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226663
NZ_CP017690.1\|WP_060475977.1\|3570274_3571411_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810
NZ_CP017690.1\|WP_008880547.1\|3569335_3569632_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP017690.1\|WP_008880558.1\|3577930_3578335_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_029761633.1\|3568173_3568401_+\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|238180
NZ_CP017690.1\|WP_008880569.1\|3584743_3585412_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP017690.1\|WP_011887614.1\|3576734_3577292_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP017690.1\|WP_021292746.1\|3579578_3580748_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP017690.1\|WP_099233500.1\|3572896_3574015_-\|acyl-CoA-desaturase	unknown	unknown	gnl\|CDD\|239583
NZ_CP017690.1\|WP_008880567.1\|3582379_3583291_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP017690.1\|WP_099233496.1\|3571492_3572275_+\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP017690.1\|WP_099233506.1\|3583400_3584747_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP017690.1\|WP_008880557.1\|3577425_3577692_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017690.1\|WP_087960107.1\|3572426_3572705_+\|DUF302-domain-containing-protein	unknown	unknown	gnl\|CDD\|269820
NZ_CP017690.1\|WP_008880545.1\|3568449_3568932_+\|DsrE/DsrF/DrsH-like-family-protein	unknown	unknown	gnl\|CDD\|379334
NZ_CP017690.1\|WP_011887613.1\|3578355_3578763_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP017690.1\|WP_008880548.1\|3569655_3570225_+\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	7.2878e-34
NZ_CP017690.1\|WP_008880546.1\|3568957_3569323_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.61715e-34
NZ_CP017690.1\|WP_099233504.1\|3574840_3575689_+\|HAD-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.27301e-73
NZ_CP017690.1\|WP_008880566.1\|3581663_3582383_-\|ABC-transporter-permease	gnl\|CDD\|226663	COG4200, COG4200, Uncharacterized protein conserved in bacteria [Function unknown].	1.50794e-31
NZ_CP017690.1\|WP_029761786.1\|3580919_3581663_-\|ABC-transporter-permease	gnl\|CDD\|226663	COG4200, COG4200, Uncharacterized protein conserved in bacteria [Function unknown].	1.3421e-32
NZ_CP017690.1\|WP_060475977.1\|3570274_3571411_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.10713e-71
NZ_CP017690.1\|WP_008880547.1\|3569335_3569632_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.62678e-30
NZ_CP017690.1\|WP_029761633.1\|3568173_3568401_+\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	2.22989e-30
NZ_CP017690.1\|WP_011887614.1\|3576734_3577292_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.51068e-59
NZ_CP017690.1\|WP_099233500.1\|3572896_3574015_-\|acyl-CoA-desaturase	gnl\|CDD\|239583	cd03506, Delta6-FADS-like, The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases are required for the synthesis of highly unsaturated fatty acids (HUFAs), which are mainly esterified into phospholipids and contribute to maintaining membrane fluidity. While HUFAs may be required for cold tolerance in bacteria, plants and fish, the primary role of HUFAs in mammals is cell signaling. These enzymes are described as front-end desaturases because they introduce a double bond between the pre-exiting double bond and the carboxyl (front) end of the fatty acid. Various substrates are involved, with both acyl-coenzyme A (CoA) and acyl-lipid desaturases present in this CD. Acyl-lipid desaturases are localized in the membranes of cyanobacterial thylakoid, plant endoplasmic reticulum (ER), and plastid; and acyl-CoA desaturases are present in ER membrane. ER-bound plant acyl-lipid desaturases and acyl-CoA desaturases require cytochrome b5 as an electron donor. Most of the eukaryotic desaturase domains have an adjacent N-terminal cytochrome b5-like domain. This domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain the residues: HXXXH, HXX(X)HH, and Q/HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homolog, stearoyl CoA desaturase.	3.36827e-38
NZ_CP017690.1\|WP_008880567.1\|3582379_3583291_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.22584e-101
NZ_CP017690.1\|WP_099233496.1\|3571492_3572275_+\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.32506e-30
NZ_CP017690.1\|WP_099233506.1\|3583400_3584747_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.08736e-35
NZ_CP017690.1\|WP_008880569.1\|3584743_3585412_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.28623e-71
NZ_CP017690.1\|WP_087960107.1\|3572426_3572705_+\|DUF302-domain-containing-protein	gnl\|CDD\|269820	cd14797, DUF302, Uncharacterized domain family DUF302. These domains are mostly found in bacterial single-domain proteins and have been shown to form homodimers; they may also bind zinc. Also characterized as COG3439.	1.8737e-26
NZ_CP017690.1\|WP_008880545.1\|3568449_3568932_+\|DsrE/DsrF/DrsH-like-family-protein	gnl\|CDD\|379334	pfam13686, DrsE_2, DsrE/DsrF/DrsH-like family. DsrE is a small soluble protein involved in intracellular sulfur reduction. The family also includes YrkE proteins.	2.50665e-79
NZ_CP017690.1\|WP_021292746.1\|3579578_3580748_+\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.742e-62

>NZ_CP017690.1|WP_099233504.1|3574840_3575689_+|HAD-family-hydrolase
MLIALDMDGTLLNGEGKISEQNRKAIMAAQAQGHLVAVVTGRARKDALAPLREAGLVCPIASLNGAIVTLEDGTVISQAPLERTVIRHALDWVREQSDLYCETYVGDEVYVGLHNRAQWEVLALEKTEVAPEVKWIVMKQFQQARVTYVDDIRTVWDDPKRVIYKLLIFSLDRERLRDAASHFDPLPGVTVTSSHPHNIEVNNERATKGEALKQLASHYGIDLRDTVVFGDSHNDLSMFEVAGCRVAMANAAPELKATCDFVTLSHEEDGVAAGLEQVLVRR
>NZ_CP017690.1|WP_099233500.1|3572896_3574015_-|acyl-CoA-desaturase
MNDFHPFGWYAAKIAPHLPKKAFQPVKSRLFGGLGYFLLVTGGILAVSLLSLHPIWNLLISVVLGFSFAALGFLGHEILHGTVVKTPWLRDLLGAIAFWPLCTGPKLWRKWHNATHHVHTQHEEKDPDAWPSMEQLAKSRLLRWVYRIPFPIRAFFAFSSLSVMFTVHSIRMLFSFFRDFRWKNRAVVLLQFFLPWTTWLGLLWLIGWEKWWFAFLLPLLIANMIVMGYISTNHRLNPLVPVNDPLANSLSVTVPKWVDVLHFNFSYHTEHHLFPAMSSKYYPLVKEHIKQMWPDRYHEMPMKKALAALWKTPRVYYEHSELIEPKQGHVYGTLGNGLDPNEIVHRELKQDAQALPTMRQEEWKKASGVGKV
>NZ_CP017690.1|WP_087960107.1|3572426_3572705_+|DUF302-domain-containing-protein
MTETRQEKGLDFSTPMVILEVCNPQEAARVLSENLLVGYFLPCKIVVYVENGVTKIGMPKPTMLVGMVSEPTLEKLAADIEKRLIACIDRCR
>NZ_CP017690.1|WP_099233496.1|3571492_3572275_+|sulfite-exporter-TauE/SafE-family-protein
MDLSLQLIIVIFLIGFIGSFISGMVGIGGSIIKYPMLLYLPPLFGLAAFSAHEVSGISAVQVFFATIGGVWAYRKGGYLNKSLILYMGASILIGSFVGGYGSKLMSEGAMNVVYGVLAALAAIMMFVPKKGIDDIPLDQVTFNKWLAAVLAFLIGIGSGIVGAAGAFLLVPVMLIVLKIPTRMTIATSLAVTFISSIGSTFGKIATGQVDYIPALIMVIASLLASPLGAKTGQKMNTKVLQVILAVLVLATAVNIWVDIL
>NZ_CP017690.1|WP_060475977.1|3570274_3571411_+|MBL-fold-metallo-hydrolase
MMKEMTVQQMTEKVLNKESLFILDVRNESDFRDWKIEGENFAYLNVPYFELVDGVDSIVDRLPKDQDIVVVCAKGGSAAFVAEQLAEAGFDNVYTLAGGMQAWSEHLHQAKVYEDDQLKIYQFIRVGKGCLSYMVLSGDEALVVDPLRFIDVYEQVAQQEGVTITHIVDSHLHADHLSGGKALAERTGAAYYLMKSEGAVFDFEPLEQHETIDFENVHLEVLAVKTPGHTPGSVSFFVNGKWLFSGDTIFVGGLGRPDLGGKVAEWAEDLYHTVYEKVAAMADDVIVLPAHYANLDEEINAEGYVGDTLGRIRARNEMMQNKAKDEFIDLVIQGAKTETPPNFEDIVAINRGLKTVDIETQRELEIGPNRCALHHTHA
>NZ_CP017690.1|WP_008880548.1|3569655_3570225_+|sulfurtransferase-TusA-family-protein
MIKVDMIVDAKGLSCPMPIVRTKKAIGELQSGQVLEVQATDKGSKADMKAWAESTGHQYLGTIEEDGVLKHYIRKSAEHETRNEVTFPHVVSNEQLQEKFHDPDSFVLDVREPAEYAFGHIPGAVSIPLGDLDSRMAELPKDKTIYVVCRTGTRSDLAAQKLAENGFDRVRNVIPGMSQWNGPLDSAQS
>NZ_CP017690.1|WP_008880547.1|3569335_3569632_+|rhodanese-like-domain-containing-protein
MKTITPKEVEERLRAGESLRIIDVREPDEVAAGKIPGAVNIPLGLIEFRMHELDKKKEYILVCRSGGRSGRAGEFLDSRGYRVVNMTGGMLAWEGPVE
>NZ_CP017690.1|WP_008880546.1|3568957_3569323_+|rhodanese-like-domain-containing-protein
MVQTVINIILFALLAWFLASRFIPPKGVQMITTAELKRRLKQSGVQYIDVRTPMEFRSFHLPGFRNIPLHELAARARELSKEKEVVVICQSGMRSQKASKWLKKMGFQHVTNVKGGLNAWQ
>NZ_CP017690.1|WP_008880545.1|3568449_3568932_+|DsrE/DsrF/DrsH-like-family-protein
MTQLKKKTTIILFSGDYDKAMAAYIIANGAAAYDHDVTIFHTFWGLNALRKEAPVPVQKGFLEKMFAKMMPRGADRMGLSRMNFAGIGPKLIKKVIKKHNAMPLPQLIEMAKEQGVKLVACQMTVDLLGLKPEELIDGIEFAGVAAYLADASEGNVNLFI
>NZ_CP017690.1|WP_029761633.1|3568173_3568401_+|sulfurtransferase-TusA-family-protein
MNVAKVLDAKGLACPMPVVRAKKAMDELQSGQVLEVHTTDKGAKNDLPAWAKASGHTVIDMKEENGVLMFWIQKG
>NZ_CP017690.1|WP_011887614.1|3576734_3577292_-|signal-peptidase-I
MGKKKSEFWGWMKTIIIAILLASSVRYFLFAPFVVEGQSMMPTLHDQDRMIVNKIKYSFVKPERFDIIVFHTKDKKDYIKRIIGLPGDRIEYKNDTLYINGKAYKEPYLDEYKKQNKSGLPLTESFTLKDTPIGRSTVPEGYLFVMGDNRRNSKDSRHIGAIPMDDVVGEANIICWPFNRIQIMK
>NZ_CP017690.1|WP_008880557.1|3577425_3577692_-|hypothetical-protein
MKGTGALLIFPFLSSFFGYTDHMEPPVIQGQVSVSISSPTESYDQSSPIQELAPQTFGASVEKSVTLPSGLHISASSSSTVIVPEFTK
>NZ_CP017690.1|WP_008880558.1|3577930_3578335_-|hypothetical-protein
MIMKKLVKTVGISAMLLAGSFVAGNAAPASAAGLGDVLGAVNSLVGETNVSSGSVVSATGPNFEIQAGSTYTNNQNGVTGLVGGVLGGTYNTNASLSGPNGLSASASTSGSYGLASSVQSLTNGLGGLLGGLLK
>NZ_CP017690.1|WP_011887613.1|3578355_3578763_-|hypothetical-protein
MKKLILSAGLSTAILMGGMGSAFAAEQPSNAPDGGLGSVLGAVNQLIGSTKVEVQSGASLKVDGVTVTAQAVNSTEQSGLTGLLSGGVLGGTSGTSASVSYAGYSASTSASGSWGLASSVQSIGGLLNSLGQSLK
>NZ_CP017690.1|WP_021292746.1|3579578_3580748_+|ISL3-family-transposase
MQSQFIKDLITLPGFLIHGERKEGERWIFELSLPPHCPICPTCFGRTTKISSKRKQWIHGYTNTVGLFWIELPIERRRCQACFLTFTVSYPGLPSHSIATESFQHWVAQLCIGKTIQEVARLLQLAYTTVERWFYQYAPALLPTSNPTVVCVDEFAFRKGHDYGVAVMDTQTRNVLSIASGKNEEAIVEALQPVASKVKYVVSDLAPAMRKAIEKVCPKAIHVLDHFHVIQLFTDALERCRKYLAKGGTKHGSVRRVCRLLSQRPEKLTEEERQEVRQWCQESAYLRDVYQALQHFRYVSKSQTRKQAETRLTQWFDRYLFSDCAAVRSIAKALITRRDAVLSCIVFSYSNGPMEGINNKIKLIKRRGYGYRNIQRFTLRVRLETSITF
>NZ_CP017690.1|WP_029761786.1|3580919_3581663_-|ABC-transporter-permease
MISLLQSEWFKLRKSKFVFTAILLGPLITFFYALMLQPDTFGLEKRFLWEFLIAFTTLLYALRFLPLTTGILAGLICRYEHQNGGWKQLLALPVTRSRVFLAKYTILMLITLTMQLLYLLAIWTSGVLKGAEEPFPMMLLWKSIFGGWIATLPLLALQLWMSMLFKSFAAPFAVNVVFTLPAILAVNSEKFGPLYPWAQPFLMMYVSGDAENDIFFVPWEQVLTVVGGSFLIFFFGGLLYFRRKENI
>NZ_CP017690.1|WP_008880566.1|3581663_3582383_-|ABC-transporter-permease
MIMKLLATDFLKIKRKGLWFLTILGPLGVVLLQWVNYELVPGRREWLLQRSDDDWLFYLQNVNSFTPLALVLGITILTSLAASIENETNAWKQLIALPISKMGVFLSKFTVLAFLLAIASVLLFFFTWLLGIYLDLGAVIPYAQIATFSFYPYFASLPLLALHLWVATVSNNQGIPISLGVIGFLFTSYSFKLPDWLPWKWPSLQNQWDEPLVNVVLGICVGIILYIIGMLDFARRDVK
>NZ_CP017690.1|WP_008880567.1|3582379_3583291_-|ABC-transporter-ATP-binding-protein
MEYIVETHHLTKRFGKEIAVNALNLKIPRGEVYGFLGPNGAGKSTTLRMLLGLMRPTAGSIRIFGKDLKKERISILRNVGSLVESPSYYSHLTAYENLEAMRKILGSPKEKIDEVLDLVRLSNAADKKVKGFSLGMKQRLGIAMALLNDPKLLILDEPTNGLDPSGIIEMRNLIKRLPKEKDITVLISSHLLSEIDQVATYVGVISKGKLIFQDSIKAMRNKAQLKIRLKVSDANNAYRSLLAKGIKTHYQDHIIYLYEQSDEAVAAVVETLVDEGYSVYRVEEEHQSLEDIFLKMTAGGDDR
>NZ_CP017690.1|WP_099233506.1|3583400_3584747_-|HAMP-domain-containing-histidine-kinase
MKSVKRLRSLTAKYMAIILTALFLIYLLIIGTSLLVFNVYDHKDPETLQIEKAWHQDARSLKNPGSEDINRMFEKWQNRYPKARLFWVDSNGRLAAGRNLAANIPKHWNAAYTANFIKARYDNDPFTVIAFPNNDASYGFVVFEIERKLLQPAFTEANADFMYFIVPGGIVLFVTVSYLFFLGIRKRLLYLQQAMEIRDVDGLPVAITVRKQDEIGQLEMAFNQMVDELRESRKREEAEEQLRKELIANLSHDLRTPLTKIRAHAYTLEKEALTPVARQAVNMIEQSVSKMDRLIENLISYTLLNAKKLKYEPTPTDVVRLARSFIAAWYPAFEKEGFCIDVQLDDLEQKHWNVDPLWMERIFDNLFQNVIRHAKDGKYIGLKTKKTDSYDALVVLDRGKGFRHKSSEKGAGIGLAIVDLMVKKMELDWKIESSETGTIITIIHYRSC
>NZ_CP017690.1|WP_008880569.1|3584743_3585412_-|response-regulator-transcription-factor
MARVLYIEDEQEIGRWVTMNLTERGHHVTWLQSGEEIEEHLAHCDLVILDVMLPGLDGFSIGKRIKKEQPDLPILMLSARTAIEDKVEGLSFADDYLTKPFHPDELAARVEVLLRRFNKNDEILKLKHLTIHTKDMRIVNHETGEEILLTGKQYQIFQYFLRHLNQILTKEQLYEGVWGEPYIEGDKTLMVHIRYLREKLEKDPKNPEIIETIRGIGYRVRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017690_1	1.12\|43372\|35\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	43372-43406	35	NC_009737	Bacillus virus 1, complete genome	25834-25868	0	1.0
NZ_CP017690_3	3.2\|1716199\|35\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716199-1716233	35	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	42343-42377	5	0.857
NZ_CP017690_3	3.17\|1717182\|38\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1717182-1717219	38	NC_029073	Geobacillus virus E3, complete genome	135980-136017	5	0.868
NZ_CP017690_1	1.15\|43571\|34\|NZ_CP017690\|CRISPRCasFinder,CRT	43571-43604	34	NZ_CP046053	Methylocystis heyeri strain H2 plasmid unnamed1, complete sequence	128717-128750	9	0.735
NZ_CP017690_1	1.6\|42975\|35\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	42975-43009	35	NC_027988	Citrobacter phage CVT22, complete genome	11472-11506	10	0.714
NZ_CP017690_3	3.8\|1716594\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716594-1716627	34	NZ_CP041206	Rhizobium sp. NIBRBAC000502774 plasmid pMK-3, complete sequence	375431-375464	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892366	Streptococcus phage SW18, complete genome	31683-31716	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892385	Streptococcus phage SW33, complete genome	33361-33394	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580775	Streptococcus phage V2, complete genome	30282-30315	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937501	Streptococcus phage CHPC1073, complete genome	29774-29807	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH000602	Streptococcus phage D5842, complete genome	31857-31890	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KX879641	Streptococcus phage CHPC577, complete genome	29008-29041	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937459	Streptococcus phage CHPC595, complete genome	30193-30226	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705261	Streptococcus phage P5652, complete genome	29223-29256	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937507	Streptococcus phage CHPC1152, complete genome	32051-32084	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705273	Streptococcus phage P7602, complete genome	32117-32150	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705274	Streptococcus phage P7631, complete genome	31777-31810	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH973662	Streptococcus phage SW7, complete genome	32304-32337	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892384	Streptococcus phage SW32, complete genome	33361-33394	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705256	Streptococcus phage P3681, complete genome	31588-31621	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937498	Streptococcus phage CHPC1057, complete genome	31461-31494	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705285	Streptococcus phage P9852, complete genome	30700-30733	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580762	Streptococcus phage 9B4, complete genome	30231-30264	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580761	Streptococcus phage 9A, complete genome	30946-30979	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937489	Streptococcus phage CHPC1034, partial genome	28817-28850	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892381	Streptococcus phage SWK5, complete genome	31638-31671	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892360	Streptococcus phage SW11, complete genome	31689-31722	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705270	Streptococcus phage P7573, complete genome	33325-33358	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	NC_007019	Streptococcus phage 2972, complete genome	31783-31816	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705275	Streptococcus phage P7632, complete genome	31599-31632	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	AY699705	Streptococcus thermophilus bacteriophage 2972, complete genome	31783-31816	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892361	Streptococcus phage SW12, complete genome	31147-31180	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580760	Streptococcus phage 7T, complete genome	30871-30904	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KT717084	Streptococcus phage 53, complete genome	29808-29841	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892363	Streptococcus phage SW14, complete genome	31025-31058	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892376	Streptococcus phage SW1151, complete genome	30405-30438	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892379	Streptococcus phage SWK3, complete genome	31417-31450	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937483	Streptococcus phage CHPC1005, complete genome	32800-32833	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KT717085	Streptococcus phage 128, complete genome	30045-30078	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892382	Streptococcus phage SWK6, complete genome	31390-31423	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705266	Streptococcus phage P7152, complete genome	31021-31054	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937480	Streptococcus phage CHPC954, complete genome	32252-32285	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937492	Streptococcus phage CHPC1040, complete genome	30514-30547	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937486	Streptococcus phage CHPC1027, complete genome	31673-31706	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892359	Streptococcus phage SW10, complete genome	30638-30671	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937500	Streptococcus phage CHPC1067, complete genome	30122-30155	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705282	Streptococcus phage P8921, complete genome	30271-30304	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705267	Streptococcus phage P7154, complete genome	30290-30323	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705268	Streptococcus phage P7571, complete genome	29748-29781	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705287	Streptococcus phage P9854, complete genome	32432-32465	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892364	Streptococcus phage SW15, complete genome	30498-30531	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892367	Streptococcus phage SW19, complete genome	29235-29268	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	NC_002072	Streptococcus phage DT1, complete genome	29629-29662	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705263	Streptococcus phage P7133, complete genome	28663-28696	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580771	Streptococcus phage MM25, complete genome	29581-29614	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937487	Streptococcus phage CHPC1029, complete genome	30415-30448	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705269	Streptococcus phage P7572, complete genome	29749-29782	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705278	Streptococcus phage P7952, complete genome	33723-33756	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892356	Streptococcus phage SW21, complete genome	31417-31450	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937465	Streptococcus phage CHPC873, complete genome	32797-32830	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705264	Streptococcus phage P7134, complete genome	29784-29817	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580763	Streptococcus phage 16B8, complete genome	29639-29672	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705276	Streptococcus phage P7633, complete genome	31102-31135	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892357	Streptococcus phage SW8, complete genome	30256-30289	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892358	Streptococcus phage SW9, complete genome	30459-30492	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	AF085222	Streptococcus thermophilus bacteriophage DT1, complete genome	29629-29662	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705283	Streptococcus phage P8922, complete genome	30292-30325	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580772	Streptococcus phage R1, complete genome	30239-30272	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892378	Streptococcus phage SWK2, complete genome	32782-32815	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705260	Streptococcus phage P5651, complete genome	29650-29683	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937484	Streptococcus phage CHPC1008, complete genome	31441-31474	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	FJ226752	Streptococcus phage ALQ13.2, complete genome	31875-31908	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705284	Streptococcus phage P9851, complete genome	31310-31343	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892383	Streptococcus phage SW31, complete genome	33361-33394	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705280	Streptococcus phage P7954, complete genome	31951-31984	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	AY196178	Streptococcus thermophilus bacteriophage kappa3 putative primase (Pri3.1) gene, complete cds	1086-1119	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MF580764	Streptococcus phage 31B4, complete genome	32182-32215	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705286	Streptococcus phage P9853, complete genome	30381-30414	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705279	Streptococcus phage P7953, complete genome	32147-32180	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937472	Streptococcus phage CHPC928, complete genome	29275-29308	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892362	Streptococcus phage SW13, complete genome	33378-33411	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705272	Streptococcus phage P7601, complete genome	30252-30285	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937488	Streptococcus phage CHPC1033, complete genome	32525-32558	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937502	Streptococcus phage CHPC1083, complete genome	32145-32178	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705262	Streptococcus phage P7132, complete genome	31420-31453	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937491	Streptococcus phage CHPC1037, partial genome	31317-31350	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH937478	Streptococcus phage CHPC951, complete genome	32120-32153	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892352	Streptococcus phage SW1, complete genome	31055-31088	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705257	Streptococcus phage P3684, complete genome	30449-30482	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892380	Streptococcus phage SWK4, complete genome	31417-31450	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	KY705265	Streptococcus phage P7151, complete genome	30383-30416	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MH892377	Streptococcus phage SWK1, complete genome	32314-32347	10	0.706
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MG708273	Streptococcus phage vB_SthS_VA698, partial genome	515-548	10	0.706
NZ_CP017690_1	1.9\|43174\|37\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	43174-43210	37	NC_018582	Gordonia sp. KTR9 plasmid pGKT1, complete sequence	60307-60343	11	0.703
NZ_CP017690_3	3.9\|1716658\|34\|NZ_CP017690\|PILER-CR,CRISPRCasFinder,CRT	1716658-1716691	34	MG708275	Streptococcus phage vB_SthS_VA460, complete genome	15626-15659	11	0.676

1. spacer 1.12|43372|35|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NC_009737 (Bacillus virus 1, complete genome) position: , mismatch: 0, identity: 1.0

aagattcatctgctgtaccaaccaacaaaacaaaa	CRISPR spacer
aagattcatctgctgtaccaaccaacaaaacaaaa	Protospacer
***********************************

2. spacer 3.2|1716199|35|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 5, identity: 0.857

tcgttccggcattggttcatcatagacgcggattt	CRISPR spacer
ccaatctggcatcggttcatcatagacgcggattt	Protospacer
.*. **.*****.**********************

3. spacer 3.17|1717182|38|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NC_029073 (Geobacillus virus E3, complete genome) position: , mismatch: 5, identity: 0.868

gataaaataaacctttcttttcccttctttccaaactt	CRISPR spacer
aataaaataaacttttctttttccttctttccaaacgc	Protospacer
.***********.********.************** .

4. spacer 1.15|43571|34|NZ_CP017690|CRISPRCasFinder,CRT matches to NZ_CP046053 (Methylocystis heyeri strain H2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

tttgacgagcatcctgaagtggcctgagggttga--	CRISPR spacer
cttgacgaccatcatgaagtggcct--tccttggtc	Protospacer
.******* **** ***********     ***.

5. spacer 1.6|42975|35|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NC_027988 (Citrobacter phage CVT22, complete genome) position: , mismatch: 10, identity: 0.714

gtaactattagaaatgctatagcatcaataaaacc	CRISPR spacer
ccagttattagaaaagctttagcatcaataccaat	Protospacer
 .*..********* *** ***********  * .

6. spacer 3.8|1716594|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041206 (Rhizobium sp. NIBRBAC000502774 plasmid pMK-3, complete sequence) position: , mismatch: 10, identity: 0.706

gctctttgcgcttcgcgttcattatccctgtgac	CRISPR spacer
gtgacataatcttcgcgttcatcatccctgtcac	Protospacer
*.  . *.  ************.******** **

7. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892366 (Streptococcus phage SW18, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

8. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892385 (Streptococcus phage SW33, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

9. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580775 (Streptococcus phage V2, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

10. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937501 (Streptococcus phage CHPC1073, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

11. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH000602 (Streptococcus phage D5842, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

12. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KX879641 (Streptococcus phage CHPC577, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

13. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937459 (Streptococcus phage CHPC595, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

14. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705261 (Streptococcus phage P5652, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

15. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937507 (Streptococcus phage CHPC1152, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

16. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705273 (Streptococcus phage P7602, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

17. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705274 (Streptococcus phage P7631, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

18. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH973662 (Streptococcus phage SW7, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

19. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892384 (Streptococcus phage SW32, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

20. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705256 (Streptococcus phage P3681, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

21. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937498 (Streptococcus phage CHPC1057, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

22. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705285 (Streptococcus phage P9852, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

23. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580762 (Streptococcus phage 9B4, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

24. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580761 (Streptococcus phage 9A, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

25. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937489 (Streptococcus phage CHPC1034, partial genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

26. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892381 (Streptococcus phage SWK5, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

27. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892360 (Streptococcus phage SW11, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

28. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705270 (Streptococcus phage P7573, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

29. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NC_007019 (Streptococcus phage 2972, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

30. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705275 (Streptococcus phage P7632, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

31. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to AY699705 (Streptococcus thermophilus bacteriophage 2972, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

32. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892361 (Streptococcus phage SW12, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

33. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580760 (Streptococcus phage 7T, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

34. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KT717084 (Streptococcus phage 53, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

35. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892363 (Streptococcus phage SW14, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

36. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892376 (Streptococcus phage SW1151, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

37. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892379 (Streptococcus phage SWK3, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

38. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937483 (Streptococcus phage CHPC1005, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

39. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KT717085 (Streptococcus phage 128, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

40. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892382 (Streptococcus phage SWK6, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

41. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705266 (Streptococcus phage P7152, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

42. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937480 (Streptococcus phage CHPC954, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

43. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937492 (Streptococcus phage CHPC1040, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

44. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937486 (Streptococcus phage CHPC1027, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

45. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892359 (Streptococcus phage SW10, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

46. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937500 (Streptococcus phage CHPC1067, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

47. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705282 (Streptococcus phage P8921, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

48. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705267 (Streptococcus phage P7154, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

49. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705268 (Streptococcus phage P7571, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

50. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705287 (Streptococcus phage P9854, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

51. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892364 (Streptococcus phage SW15, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

52. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892367 (Streptococcus phage SW19, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

53. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NC_002072 (Streptococcus phage DT1, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

54. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705263 (Streptococcus phage P7133, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

55. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580771 (Streptococcus phage MM25, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

56. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937487 (Streptococcus phage CHPC1029, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

57. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705269 (Streptococcus phage P7572, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

58. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705278 (Streptococcus phage P7952, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

59. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892356 (Streptococcus phage SW21, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

60. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937465 (Streptococcus phage CHPC873, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

61. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705264 (Streptococcus phage P7134, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

62. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580763 (Streptococcus phage 16B8, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

63. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705276 (Streptococcus phage P7633, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

64. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892357 (Streptococcus phage SW8, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

65. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892358 (Streptococcus phage SW9, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

66. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to AF085222 (Streptococcus thermophilus bacteriophage DT1, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

67. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705283 (Streptococcus phage P8922, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

68. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580772 (Streptococcus phage R1, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

69. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892378 (Streptococcus phage SWK2, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

70. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705260 (Streptococcus phage P5651, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

71. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937484 (Streptococcus phage CHPC1008, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

72. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to FJ226752 (Streptococcus phage ALQ13.2, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

73. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705284 (Streptococcus phage P9851, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

74. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892383 (Streptococcus phage SW31, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

75. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705280 (Streptococcus phage P7954, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

76. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to AY196178 (Streptococcus thermophilus bacteriophage kappa3 putative primase (Pri3.1) gene, complete cds) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

77. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MF580764 (Streptococcus phage 31B4, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

78. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705286 (Streptococcus phage P9853, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

79. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705279 (Streptococcus phage P7953, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

80. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937472 (Streptococcus phage CHPC928, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

81. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892362 (Streptococcus phage SW13, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

82. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705272 (Streptococcus phage P7601, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

83. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937488 (Streptococcus phage CHPC1033, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

84. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937502 (Streptococcus phage CHPC1083, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

85. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705262 (Streptococcus phage P7132, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

86. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937491 (Streptococcus phage CHPC1037, partial genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

87. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH937478 (Streptococcus phage CHPC951, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

88. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892352 (Streptococcus phage SW1, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

89. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705257 (Streptococcus phage P3684, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

90. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892380 (Streptococcus phage SWK4, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

91. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to KY705265 (Streptococcus phage P7151, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

92. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MH892377 (Streptococcus phage SWK1, complete genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

93. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MG708273 (Streptococcus phage vB_SthS_VA698, partial genome) position: , mismatch: 10, identity: 0.706

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatca	Protospacer
  *** ****** *************.*... .*

94. spacer 1.9|43174|37|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to NC_018582 (Gordonia sp. KTR9 plasmid pGKT1, complete sequence) position: , mismatch: 11, identity: 0.703

aaggagcgagcagacgcgagcgacggaagggggagcg	CRISPR spacer
aaggagcgagcagacgccagcgccggtgtccatggcc	Protospacer
***************** **** *** .   . .**

95. spacer 3.9|1716658|34|NZ_CP017690|PILER-CR,CRISPRCasFinder,CRT matches to MG708275 (Streptococcus phage vB_SthS_VA460, complete genome) position: , mismatch: 11, identity: 0.676

caattgcaaaacgtctttacgattgacgcggata	CRISPR spacer
atattccaaaacttctttacgattgatgtaatcg	Protospacer
  *** ****** *************.*... ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1058561 : 1092466

Enterobacteria_phage(33.33%)

transposase,protease,integrase

attL 1085063:1085076|attR 1094014:1094027

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008878794.1\|1058561_1059113_+\|protease	spore protease YyaC	NA	NA	NA	NA
WP_008878795.1\|1059159_1060881_-	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_008878796.1\|1060880_1061144_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_081157281.1\|1061255_1063271_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_008878798.1\|1063510_1064368_-	transcription antiterminator	NA	NA	NA	NA
WP_008878799.1\|1064526_1065348_+	alpha/beta hydrolase	R4JP33	Mycobacterium_phage	5.2e-05	29.6
WP_171355325.1\|1065523_1066150_+	nitroreductase family protein	NA	NA	NA	NA
WP_081157282.1\|1066207_1067485_-	PAS domain-containing protein	A0A1V0SGX0	Hokovirus	5.4e-17	26.8
WP_008878803.1\|1067540_1067786_-	YueH family protein	NA	NA	NA	NA
WP_035499108.1\|1067853_1068603_-	glucose 1-dehydrogenase	NA	NA	NA	NA
WP_060475710.1\|1068871_1069516_-	hypothetical protein	NA	NA	NA	NA
WP_008878806.1\|1069686_1069881_+	hypothetical protein	NA	NA	NA	NA
WP_008878807.1\|1070074_1070662_+	cell wall hydrolase	A0A0E3XAL9	Bacillus_phage	8.2e-45	48.1
WP_087959914.1\|1070873_1071299_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_008881762.1\|1071390_1071771_-	hypothetical protein	NA	NA	NA	NA
WP_099232911.1\|1074457_1075711_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	1.4e-09	25.3
WP_011230382.1\|1075703_1076504_+	ExeA family protein	NA	NA	NA	NA
WP_008881771.1\|1078414_1078765_-	DUF3221 domain-containing protein	NA	NA	NA	NA
WP_081157650.1\|1079208_1079973_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	5.5e-49	39.9
WP_081157651.1\|1079969_1081538_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_009361858.1\|1082684_1083440_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	9.2e-57	47.7
WP_015375695.1\|1083851_1084985_+\|transposase	IS4 family transposase	NA	NA	NA	NA
1085063:1085076	attL	NA	NA	NA	NA
WP_015864897.1\|1085296_1085461_-	hypothetical protein	NA	NA	NA	NA
WP_015864898.1\|1085575_1085986_-	DUF3021 domain-containing protein	NA	NA	NA	NA
WP_015864899.1\|1085982_1086441_-	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_052510034.1\|1089458_1089830_-	DUF3888 domain-containing protein	NA	NA	NA	NA
WP_042409697.1\|1089984_1090365_-\|transposase	transposase	NA	NA	NA	NA
WP_042409700.1\|1090357_1092466_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1094014:1094027	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1166611 : 1176443

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008878886.1\|1166611_1167646_-	ribonucleotide-diphosphate reductase subunit beta	A0A127AVZ3	Bacillus_phage	1.3e-122	61.4
WP_099232927.1\|1167751_1170034_-	ribonucleoside-diphosphate reductase subunit alpha	A0A0Y0AS84	Bacillus_phage	2.8e-306	68.6
WP_081157187.1\|1170547_1171558_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.4e-20	29.1
WP_008878889.1\|1171559_1172351_+	ABC transporter permease	NA	NA	NA	NA
WP_008878890.1\|1172581_1173256_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.8e-78	64.4
WP_099232929.1\|1173252_1174317_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.6e-89	50.6
WP_011886997.1\|1174535_1176443_-	asparagine synthase (glutamine-hydrolyzing)	A0A1V0SGM7	Hokovirus	4.6e-36	31.0

DBSCAN-SWA_3

1188627 : 1205946

Burkholderia_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172437878.1\|1188627_1190295_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_087959898.1\|1190872_1191214_+	hypothetical protein	NA	NA	NA	NA
WP_087959896.1\|1191974_1192943_+	hypothetical protein	NA	NA	NA	NA
WP_099232940.1\|1193313_1194542_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_087959846.1\|1195106_1196384_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_021292746.1\|1196645_1197815_+\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	3.3e-21	26.3
WP_025950780.1\|1197964_1198342_+	hypothetical protein	NA	NA	NA	NA
WP_087959893.1\|1199104_1200307_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	6.0e-50	37.6
WP_009361858.1\|1200303_1201059_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	9.2e-57	47.7
WP_087959892.1\|1203899_1204700_-	ExeA family protein	NA	NA	NA	NA
WP_099232911.1\|1204692_1205946_-\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	1.4e-09	25.3

DBSCAN-SWA_4

1549601 : 1588479

Aeribacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099233567.1\|1549601_1550829_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_011886784.1\|1551022_1551811_-	recombinase family protein	A0A1L2JY12	Aeribacillus_phage	5.2e-18	28.7
WP_011886783.1\|1552221_1552683_-	hypothetical protein	NA	NA	NA	NA
WP_087959816.1\|1553079_1554360_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_011886780.1\|1555570_1555996_-	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_171355695.1\|1556013_1556421_-	hypothetical protein	NA	NA	NA	NA
WP_011886778.1\|1556472_1556952_-	pre-toxin TG domain-containing protein	NA	NA	NA	NA
WP_099232992.1\|1557348_1557849_-	maleate cis-trans isomerase	NA	NA	NA	NA
WP_015374822.1\|1558003_1559509_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_042412494.1\|1559767_1560325_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_021292743.1\|1560465_1561719_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	1.1e-09	25.3
WP_011230382.1\|1561711_1562512_+	ExeA family protein	NA	NA	NA	NA
WP_008881167.1\|1564012_1564294_-	hypothetical protein	NA	NA	NA	NA
WP_029761977.1\|1565461_1565812_-	hypothetical protein	NA	NA	NA	NA
WP_008881171.1\|1566930_1567278_-	DUF5082 domain-containing protein	NA	NA	NA	NA
WP_060475596.1\|1567324_1567807_-	type VII secretion protein EssA	NA	NA	NA	NA
WP_008881173.1\|1567796_1570577_-	type VII secretion protein EsaA	NA	NA	NA	NA
WP_099232996.1\|1570600_1575040_-	type VII secretion protein EssC	V5UPA0	Mycobacterium_phage	3.2e-40	22.1
WP_081157540.1\|1575076_1576363_-	type VII secretion protein EssB	NA	NA	NA	NA
WP_008881176.1\|1576397_1576637_-	hypothetical protein	NA	NA	NA	NA
WP_008881177.1\|1576867_1577161_-	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_008881178.1\|1577437_1577770_-	hypothetical protein	NA	NA	NA	NA
WP_099232998.1\|1577785_1579714_-	flagellar protein FlgN	NA	NA	NA	NA
WP_060475594.1\|1579728_1580328_-	hypothetical protein	NA	NA	NA	NA
WP_099233569.1\|1580979_1581579_-	hypothetical protein	NA	NA	NA	NA
WP_099233000.1\|1585507_1585945_+	hypothetical protein	NA	NA	NA	NA
WP_081157653.1\|1585957_1586263_+	hypothetical protein	NA	NA	NA	NA
WP_158083266.1\|1586489_1587050_-	replication initiation protein	NA	NA	NA	NA
WP_014195313.1\|1587948_1588479_+\|transposase	IS630 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1696000 : 1748538

Erysipelothrix_phage(14.29%)

transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087960193.1\|1696000_1697290_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.1e-52	34.2
WP_008881271.1\|1697394_1697685_-	hypothetical protein	NA	NA	NA	NA
WP_008881273.1\|1700039_1700822_+	helix-turn-helix transcriptional regulator	D2XQ11	Bacillus_virus	9.1e-07	35.7
WP_029761504.1\|1701613_1702024_-\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	1.8e-51	68.1
WP_011886727.1\|1702260_1703652_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	1.1e-50	30.7
WP_008881301.1\|1703926_1705159_+	serine/threonine transporter SstT	NA	NA	NA	NA
WP_011886726.1\|1705654_1705834_-	hypothetical protein	NA	NA	NA	NA
WP_029761506.1\|1706028_1707498_-	alanine:cation symporter family protein	NA	NA	NA	NA
WP_087959841.1\|1708917_1709403_-	hypothetical protein	NA	NA	NA	NA
WP_011886722.1\|1710012_1710603_-	GrpB family protein	NA	NA	NA	NA
WP_099233036.1\|1710722_1711520_-	nucleotidyltransferase domain-containing protein	A0A1X9I6C9	Streptococcus_phage	2.9e-125	78.5
WP_015374614.1\|1711529_1712663_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_099233038.1\|1713173_1713977_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_099233040.1\|1713969_1714530_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_008881400.1\|1714522_1714846_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_008881404.1\|1718164_1718515_-	DUF2200 domain-containing protein	NA	NA	NA	NA
WP_099233042.1\|1718915_1719272_-	YxeA family protein	NA	NA	NA	NA
WP_011886719.1\|1719296_1721168_-	ABC transporter permease	NA	NA	NA	NA
WP_011886718.1\|1721142_1721916_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-27	36.1
WP_011886717.1\|1722253_1723639_+	L-cystine transporter	NA	NA	NA	NA
WP_087959836.1\|1724307_1725690_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	2.3e-122	48.1
WP_008881410.1\|1725764_1726685_-	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	2.3e-25	30.9
WP_081157607.1\|1726828_1728349_-	flotillin family protein	A0A2I2L4B2	Orpheovirus	1.2e-07	27.7
WP_008881412.1\|1728370_1728907_-	NfeD family protein	NA	NA	NA	NA
WP_060475550.1\|1729724_1731443_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_029761619.1\|1731753_1733199_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_081157625.1\|1733573_1734320_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_008881416.1\|1734346_1735420_-	tartrate dehydrogenase	NA	NA	NA	NA
WP_029761618.1\|1735423_1736653_-	M20 family metallopeptidase	NA	NA	NA	NA
WP_060475548.1\|1736656_1738126_-	sodium/panthothenate symporter	NA	NA	NA	NA
WP_171355685.1\|1738122_1738410_-	DUF997 family protein	NA	NA	NA	NA
WP_087959814.1\|1738814_1739984_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	2.5e-24	25.1
WP_060475547.1\|1740614_1741823_-	trypsin-like peptidase domain-containing protein	W5SAB9	Pithovirus	7.0e-14	29.9
WP_008881421.1\|1742185_1742848_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.2e-31	34.7
WP_029761614.1\|1742837_1744211_+	GHKL domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	2.3e-13	26.8
WP_029761613.1\|1744380_1744902_+	hypothetical protein	NA	NA	NA	NA
WP_029761612.1\|1744861_1745515_+	PspA/IM30 family protein	NA	NA	NA	NA
WP_008881425.1\|1745688_1746927_+	MFS transporter	NA	NA	NA	NA
WP_033025194.1\|1747401_1748538_+\|transposase	IS110-like element ISGka2 family transposase	Q9JMN8	Wolbachia_phage	2.7e-36	28.9

DBSCAN-SWA_6

1795665 : 1804055

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081157373.1\|1795665_1796295_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	3.0e-24	35.2
WP_008881461.1\|1796291_1797332_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	8.5e-69	47.0
WP_008881462.1\|1797429_1798842_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.4e-51	34.9
WP_008881463.1\|1798817_1801046_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.1e-166	41.7
WP_081157372.1\|1801029_1801716_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_008881465.1\|1801712_1801967_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_029761594.1\|1801954_1802683_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	1.6e-45	42.4
WP_008881467.1\|1802759_1804055_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.7e-18	24.3

DBSCAN-SWA_7

2113614 : 2123409

Streptococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008880808.1\|2113614_2114979_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.8e-122	52.4
WP_008880807.1\|2115138_2116425_+	adenylosuccinate synthase	L7Y4J5	Megavirus	1.7e-71	36.4
WP_008880805.1\|2116649_2117363_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.0e-44	42.3
WP_081157359.1\|2117369_2119199_+	cell wall metabolism sensor histidine kinase WalK	A0A1V0SGX0	Hokovirus	1.1e-23	27.5
WP_008880803.1\|2119191_2120520_+	hypothetical protein	NA	NA	NA	NA
WP_008880802.1\|2120506_2121289_+	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_008880801.1\|2121295_2122090_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.6e-43	36.9
WP_035499498.1\|2122191_2123409_+	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	3.6e-18	27.3

DBSCAN-SWA_8

2444751 : 2502407

Streptococcus_phage(36.36%)

transposase,integrase

attL 2465160:2465175|attR 2505796:2505811

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081157651.1\|2444751_2446320_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_081157650.1\|2446316_2447081_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	5.5e-49	39.9
WP_099233147.1\|2447177_2448416_-	replication-relaxation family protein	NA	NA	NA	NA
WP_031406929.1\|2450164_2451400_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	6.9e-142	63.0
WP_099233149.1\|2452301_2452910_+	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	NA	NA	NA	NA
WP_099233151.1\|2452909_2453821_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_099233153.1\|2454022_2455591_+\|transposase	IS1182 family transposase	Q9MBP7	Staphylococcus_prophage	1.6e-71	33.2
WP_099233155.1\|2456081_2458157_+	hypothetical protein	NA	NA	NA	NA
WP_008880572.1\|2458538_2459708_+\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	1.9e-24	25.2
WP_011888231.1\|2460780_2461983_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_099233157.1\|2461997_2462666_-	hypothetical protein	NA	NA	NA	NA
WP_011888229.1\|2462823_2464032_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_011888228.1\|2464054_2465311_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
2465160:2465175	attL	NA	NA	NA	NA
WP_011888227.1\|2465335_2465704_-	EamA family transporter	NA	NA	NA	NA
WP_029761369.1\|2465690_2466059_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_011888225.1\|2466074_2466761_-	glycosyltransferase family 2 protein	I1TED8	Salmonella_phage	8.8e-06	27.6
WP_081157677.1\|2466930_2468367_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1X9I6E7	Streptococcus_phage	5.4e-05	32.5
WP_011888224.1\|2469223_2471590_+	accessory Sec system translocase SecA2	NA	NA	NA	NA
WP_099233158.1\|2471603_2472479_+	accessory Sec system S-layer assembly protein	NA	NA	NA	NA
WP_011888222.1\|2473026_2474091_+	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
WP_171355362.1\|2474512_2475520_-	LCP family protein	A0A1X9I5X1	Streptococcus_phage	4.7e-24	29.3
WP_011888220.1\|2475550_2476195_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	5.9e-36	39.1
WP_008880360.1\|2476414_2477599_+	sensor histidine kinase	NA	NA	NA	NA
WP_008880359.1\|2477595_2478273_+	response regulator transcription factor	NA	NA	NA	NA
WP_011888218.1\|2478745_2479591_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	8.3e-14	35.4
WP_035499366.1\|2480362_2481739_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	2.2e-64	39.0
WP_099233162.1\|2481735_2482428_+	ComF family protein	NA	NA	NA	NA
WP_099233589.1\|2485927_2486224_+	EscU/YscU/HrcU family type III secretion system export apparatus switch protein	NA	NA	NA	NA
WP_099233591.1\|2486282_2486720_+	flagellar export chaperone FliS	NA	NA	NA	NA
WP_008880352.1\|2486726_2488511_+	flagellar protein	NA	NA	NA	NA
WP_008880351.1\|2488595_2489033_+	YaaR family protein	NA	NA	NA	NA
WP_011888210.1\|2489065_2489488_+	membrane protein	NA	NA	NA	NA
WP_099233164.1\|2489559_2489826_+	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
WP_008880348.1\|2489841_2490309_+	flagellar protein FlgN	NA	NA	NA	NA
WP_099233166.1\|2490320_2491907_+	flagellar hook-associated protein FlgK	NA	NA	NA	NA
WP_099233168.1\|2491917_2492811_+	flagellar hook-associated protein FlgL	NA	NA	NA	NA
WP_099233170.1\|2492894_2493449_+	hypothetical protein	NA	NA	NA	NA
WP_099233172.1\|2493471_2493906_+	flagellar assembly protein FliW	NA	NA	NA	NA
WP_099233174.1\|2493922_2494171_+	carbon storage regulator CsrA	H2BD56	Pseudomonas_phage	2.0e-08	58.8
WP_062679055.1\|2494167_2494353_+	hypothetical protein	NA	NA	NA	NA
WP_099233593.1\|2494719_2496114_+	flagellin	NA	NA	NA	NA
WP_099233178.1\|2497146_2497437_+	hypothetical protein	NA	NA	NA	NA
WP_099233180.1\|2498108_2498438_+	hypothetical protein	NA	NA	NA	NA
WP_099233182.1\|2500025_2500970_-	endonuclease	NA	NA	NA	NA
WP_087959816.1\|2501126_2502407_+\|transposase	IS110 family transposase	NA	NA	NA	NA
2505796:2505811	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2750882 : 2760097

Staphylococcus_phage(57.14%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087960383.1\|2750882_2751119_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	3.9e-22	63.5
WP_008880964.1\|2751316_2751793_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_008880963.1\|2751817_2752033_-	YtzI protein	NA	NA	NA	NA
WP_081157198.1\|2752127_2752568_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	8.0e-53	69.2
WP_008880961.1\|2752710_2753106_+\|holin	phage holin family protein	A0A0N7GFE6	Paenibacillus_phage	1.8e-24	49.6
WP_008880960.1\|2753359_2753698_+	hypothetical protein	NA	NA	NA	NA
WP_029760561.1\|2753756_2754224_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	8.6e-21	36.8
WP_008880958.1\|2754276_2755086_-	ABC transporter permease	NA	NA	NA	NA
WP_008880957.1\|2755072_2755891_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.2e-31	34.6
WP_029760563.1\|2755909_2756914_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008880955.1\|2757132_2757921_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.6e-33	36.9
WP_008880954.1\|2758069_2758312_+	DUF2584 domain-containing protein	NA	NA	NA	NA
WP_008880953.1\|2758510_2760097_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	7.3e-197	64.4

DBSCAN-SWA_10

2767624 : 2831377

Staphylococcus_phage(31.25%)

transposase,tRNA,integrase

attL 2798006:2798065|attR 2829704:2831508

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008880943.1\|2767624_2770042_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	75.4
WP_029760579.1\|2770105_2770420_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	3.1e-14	45.8
WP_008880941.1\|2770661_2770841_+	sporulation protein Cse60	NA	NA	NA	NA
WP_099233268.1\|2770973_2772275_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	1.8e-28	59.0
WP_060476120.1\|2772389_2774015_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_008880938.1\|2774120_2774321_-	hypothetical protein	NA	NA	NA	NA
WP_008880937.1\|2774424_2775171_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_008880936.1\|2775268_2775490_-	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_078172648.1\|2775739_2777152_+	dipeptidase PepV	NA	NA	NA	NA
WP_060476119.1\|2777234_2778431_+	MFS transporter	NA	NA	NA	NA
WP_011887999.1\|2778427_2779006_+	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_008880932.1\|2779017_2779959_+	hypothetical protein	NA	NA	NA	NA
WP_099233270.1\|2780064_2782245_+	type I pullulanase	NA	NA	NA	NA
WP_008880930.1\|2782473_2783256_+	phosphotransferase family protein	NA	NA	NA	NA
WP_008880929.1\|2783352_2783622_-	hypothetical protein	NA	NA	NA	NA
WP_060476115.1\|2783769_2784420_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_008880927.1\|2784678_2785530_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_029760589.1\|2785524_2785821_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_008880925.1\|2785933_2787010_+	M42 family metallopeptidase	NA	NA	NA	NA
WP_008880924.1\|2787112_2787643_+	DUF84 family protein	NA	NA	NA	NA
WP_008880923.1\|2787689_2788487_+	DUF1444 domain-containing protein	A0A2H4PQY3	Staphylococcus_phage	1.5e-36	56.9
WP_008880922.1\|2788508_2789114_+	DUF4479 domain-containing protein	NA	NA	NA	NA
WP_099233272.1\|2789220_2792313_+	DNA translocase FtsK	G1D482	Mycobacterium_virus	2.6e-89	50.3
WP_008880920.1\|2792440_2793745_+	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_008880919.1\|2794006_2794456_+	DUF948 domain-containing protein	NA	NA	NA	NA
WP_008880918.1\|2794442_2794826_+	YtxH domain-containing protein	NA	NA	NA	NA
WP_029760596.1\|2794831_2795164_+	bacillithiol system redox-active protein YtxJ	NA	NA	NA	NA
WP_008880916.1\|2795407_2796490_+	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	E3T537	Cafeteria_roenbergensis_virus	2.5e-15	28.9
WP_011887988.1\|2796963_2797959_+	catabolite control protein A	NA	NA	NA	NA
2798006:2798065	attL	NA	NA	NA	NA
WP_087959916.1\|2798110_2799679_-\|transposase	IS1182 family transposase	Q9MBP7	Staphylococcus_prophage	4.7e-71	33.2
WP_087959838.1\|2801671_2802839_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.4e-59	42.8
WP_172437890.1\|2804275_2804743_+	ABC transporter permease	NA	NA	NA	NA
WP_099233276.1\|2804891_2805734_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_034839221.1\|2805726_2806440_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_099233278.1\|2807188_2807491_+	hypothetical protein	NA	NA	NA	NA
WP_008880914.1\|2807744_2808914_-	acetoin utilization protein AcuC	NA	NA	NA	NA
WP_008880913.1\|2808910_2809555_-	CBS domain-containing protein	NA	NA	NA	NA
WP_081157677.1\|2809724_2811161_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1X9I6E7	Streptococcus_phage	5.4e-05	32.5
WP_008880912.1\|2811440_2812073_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_008880911.1\|2812248_2813964_+	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	9.3e-214	74.8
WP_008880910.1\|2814262_2817022_-	transglycosylase domain-containing protein	NA	NA	NA	NA
WP_081157600.1\|2817457_2818717_+\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	1.5e-83	41.4
WP_099233280.1\|2819739_2820171_+	PAS domain S-box protein	NA	NA	NA	NA
WP_099233282.1\|2820233_2821280_+\|transposase	IS630-like element ISBs2 family transposase	NA	NA	NA	NA
WP_087960193.1\|2822116_2823406_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.1e-52	34.2
WP_060476369.1\|2823398_2824157_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	6.6e-55	45.5
WP_011230088.1\|2825643_2826012_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	1.8e-50	78.7
WP_011230089.1\|2826004_2828143_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	0.0e+00	84.8
WP_087959916.1\|2829808_2831377_-\|transposase	IS1182 family transposase	Q9MBP7	Staphylococcus_prophage	4.7e-71	33.2
2829704:2831508	attR	NA	NA	NA	NA

DBSCAN-SWA_11

2969749 : 3027037

Bacillus_virus(20.0%)

protease,coat,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011887922.1\|2969749_2971015_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.1e-150	67.7
WP_008881109.1\|2971155_2972832_+\|protease	ATP-dependent protease LonB	A0A076FMQ5	Aureococcus_anophage	1.8e-12	32.2
WP_011887921.1\|2973101_2975444_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	2.8e-184	45.0
WP_008881107.1\|2975440_2976028_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_099233306.1\|2976101_2976587_-	hypothetical protein	NA	NA	NA	NA
WP_011887920.1\|2976751_2978119_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_008881104.1\|2978129_2978945_+	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_008881103.1\|2978960_2979890_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_008881102.1\|2979889_2980660_+	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_011887919.1\|2980660_2981635_+	porphobilinogen synthase	NA	NA	NA	NA
WP_008881100.1\|2981650_2982940_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_008881099.1\|2983058_2984123_+	stage VI sporulation protein D	NA	NA	NA	NA
WP_008881098.1\|2984166_2985198_+\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_008881097.1\|2985194_2985383_-	hypothetical protein	NA	NA	NA	NA
WP_008881096.1\|2985967_2988610_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	5.5e-165	42.0
WP_099233308.1\|2988740_2990045_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_087960167.1\|2990103_2992110_+	VWA domain-containing protein	NA	NA	NA	NA
WP_087960166.1\|2992218_2993796_-	hypothetical protein	NA	NA	NA	NA
WP_008881092.1\|2993812_2994388_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_008881091.1\|2994371_2994983_-	hypothetical protein	NA	NA	NA	NA
WP_011887916.1\|2995107_2996454_+	hypothetical protein	NA	NA	NA	NA
WP_087960165.1\|2996823_2998191_+	VanW family protein	NA	NA	NA	NA
WP_099233310.1\|2998187_2999852_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_099233312.1\|2999864_3000920_+	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_029760649.1\|3000906_3002118_+	type II secretion system F family protein	NA	NA	NA	NA
WP_171355523.1\|3002204_3002687_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_011887913.1\|3002692_3003439_+	prepilin peptidase	NA	NA	NA	NA
WP_008881083.1\|3003464_3004397_+	pilus assembly protein PilM	NA	NA	NA	NA
WP_008881082.1\|3004386_3004962_+	fimbrial protein	NA	NA	NA	NA
WP_011887912.1\|3004958_3005627_+	pilus assembly protein PilO	NA	NA	NA	NA
WP_029760654.1\|3005645_3006080_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_008881079.1\|3006196_3007321_+	hypothetical protein	NA	NA	NA	NA
WP_008881078.1\|3007439_3008021_+	septum formation inhibitor Maf	NA	NA	NA	NA
WP_171355528.1\|3008145_3008817_+	DNA repair protein RadC	NA	NA	NA	NA
WP_008881075.1\|3008974_3009997_+	rod shape-determining protein	NA	NA	NA	NA
WP_008881074.1\|3010017_3010884_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_011887910.1\|3010880_3011399_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_011887909.1\|3011448_3012132_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_008881070.1\|3012134_3012938_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_011887908.1\|3013372_3014140_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_029760656.1\|3014132_3014993_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_008881067.1\|3015238_3015547_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_011887906.1\|3015550_3015883_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_008881065.1\|3015898_3016189_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_099233314.1\|3016366_3016927_+	Spo0B domain-containing protein	NA	NA	NA	NA
WP_011887904.1\|3017021_3018323_+	GTPase ObgE	NA	NA	NA	NA
WP_008881062.1\|3018340_3018784_+	ACT domain-containing protein	NA	NA	NA	NA
WP_011887902.1\|3018805_3019654_+	prephenate dehydratase	NA	NA	NA	NA
WP_011887901.1\|3019932_3020481_-	transcription repressor NadR	NA	NA	NA	NA
WP_008881059.1\|3020468_3021614_-	IscS subfamily cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	9.5e-29	27.3
WP_060476083.1\|3021718_3023281_+	L-aspartate oxidase	NA	NA	NA	NA
WP_008881057.1\|3023313_3024144_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_011887898.1\|3024158_3025262_+	quinolinate synthase NadA	NA	NA	NA	NA
WP_099233317.1\|3025420_3027037_+\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA

DBSCAN-SWA_12

3294879 : 3305357

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008879706.1\|3294879_3295980_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.1e-58	38.8
WP_011887733.1\|3295979_3296624_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.5e-39	44.6
WP_008879704.1\|3296647_3297841_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	8.7e-118	54.1
WP_011887731.1\|3297858_3298323_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	8.8e-42	60.4
WP_008879702.1\|3298443_3298794_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_008879701.1\|3298849_3299362_-	DUF309 domain-containing protein	NA	NA	NA	NA
WP_172437904.1\|3299628_3300384_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.5e-09	26.1
WP_008879699.1\|3300615_3301245_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.5e-15	34.9
WP_029761016.1\|3301291_3301690_+	hypothetical protein	NA	NA	NA	NA
WP_051358518.1\|3302123_3302378_-	hypothetical protein	NA	NA	NA	NA
WP_099233381.1\|3302562_3303912_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.8e-39	45.0
WP_029761014.1\|3304211_3305357_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.1e-21	33.6

DBSCAN-SWA_13

3368759 : 3379465

Pandoravirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008879623.1\|3368759_3369032_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	3.5e-30	78.9
WP_029760976.1\|3369165_3369732_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	4.8e-50	54.9
WP_008879621.1\|3369744_3369969_+	trp RNA-binding attenuation protein MtrB	NA	NA	NA	NA
WP_029760975.1\|3370082_3370862_+	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_029760974.1\|3370866_3371571_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_008879618.1\|3371587_3372550_+	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	1.1e-06	23.6
WP_008879617.1\|3372647_3373097_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	7.0e-28	46.2
WP_008879616.1\|3373175_3373946_+	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_008879615.1\|3374047_3375214_+	chorismate synthase	A0A291AU41	Pandoravirus	3.8e-41	36.2
WP_011887695.1\|3375216_3376317_+	3-dehydroquinate synthase	E5ERI4	Ostreococcus_lucimarinus_virus	4.8e-22	28.5
WP_008879613.1\|3376313_3376694_+	chorismate mutase	NA	NA	NA	NA
WP_008879612.1\|3376925_3378452_+	anthranilate synthase component I	S4VNU7	Pandoravirus	9.0e-35	37.7
WP_008879611.1\|3378445_3379465_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	2.4e-68	42.2

DBSCAN-SWA_14

3427692 : 3524115

Geobacillus_phage(19.57%)

transposase,portal,terminase,capsid,integrase,protease,head,tail

attL 3429912:3429928|attR 3528771:3528787

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081157677.1\|3427692_3429129_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1X9I6E7	Streptococcus_phage	5.4e-05	32.5
WP_099233415.1\|3429419_3430661_+	extracellular solute-binding protein	NA	NA	NA	NA
3429912:3429928	attL	NA	NA	NA	NA
WP_099233417.1\|3430742_3431672_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_033014063.1\|3431671_3432490_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_099233420.1\|3432579_3434769_+	alpha-galactosidase	NA	NA	NA	NA
WP_029760954.1\|3434826_3435609_-	EcsC family protein	NA	NA	NA	NA
WP_008879557.1\|3435766_3436951_+	galactokinase	NA	NA	NA	NA
WP_011887667.1\|3436947_3437934_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	4.0e-52	37.5
WP_099233423.1\|3437936_3439463_+	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_011887665.1\|3439519_3440542_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_008879553.1\|3440557_3441001_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_008879552.1\|3441065_3441356_-	hypothetical protein	NA	NA	NA	NA
WP_099233425.1\|3447634_3448768_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	7.3e-106	51.6
WP_008881998.1\|3448809_3449244_-	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	1.0e-71	89.5
WP_008881997.1\|3449265_3449736_-	hypothetical protein	S6C481	Thermus_phage	1.9e-44	72.2
WP_131261719.1\|3449944_3450169_+	XRE family transcriptional regulator	NA	NA	NA	NA
WP_008881995.1\|3450165_3450891_+	phage antirepressor Ant	A0A2P1JTZ2	Anoxybacillus_phage	2.8e-95	72.2
WP_099233617.1\|3451086_3451335_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_099233427.1\|3451306_3451579_+	hypothetical protein	NA	NA	NA	NA
WP_008881991.1\|3452111_3452306_+	hypothetical protein	A6M980	Geobacillus_virus	3.2e-22	73.3
WP_008881990.1\|3452329_3452806_+	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	1.8e-53	72.3
WP_008881989.1\|3452802_3453504_+	ERF family protein	A0A1J0MFT8	Staphylococcus_phage	3.6e-39	44.4
WP_008881988.1\|3453500_3453662_+	hypothetical protein	NA	NA	NA	NA
WP_008881986.1\|3453909_3454731_+	DnaD domain protein	A0A0U4JX08	Bacillus_phage	9.1e-42	69.2
WP_008881985.1\|3454746_3455010_+	hypothetical protein	NA	NA	NA	NA
WP_099233429.1\|3455006_3456254_+	DNA helicase	A0A0U4B0A1	Bacillus_phage	3.5e-77	37.3
WP_008880429.1\|3456258_3456687_+	hypothetical protein	NA	NA	NA	NA
WP_008880430.1\|3456683_3457142_+	HNH endonuclease	A6M989	Geobacillus_virus	2.6e-38	59.7
WP_008880432.1\|3457231_3457729_+	single-stranded DNA-binding protein	A6M990	Geobacillus_virus	9.1e-45	57.9
WP_041264900.1\|3457807_3458101_+	hypothetical protein	NA	NA	NA	NA
WP_013144080.1\|3458192_3458375_+	hypothetical protein	NA	NA	NA	NA
WP_011888079.1\|3458393_3458942_+	dUTP diphosphatase	A0A290GJJ6	Caldibacillus_phage	4.1e-30	39.3
WP_008881975.1\|3458955_3459447_+	hypothetical protein	A0A0C5AFC9	Paenibacillus_phage	1.0e-32	51.4
WP_011888077.1\|3459459_3459882_+	hypothetical protein	A6M9A1	Geobacillus_virus	9.1e-46	62.7
WP_099233431.1\|3459923_3460352_+	transcriptional regulator	E5DV97	Deep-sea_thermophilic_phage	4.6e-45	60.0
WP_099233433.1\|3460592_3460955_-	response regulator	Q56AR1	Bacillus_thuringiensis_phage	1.7e-08	36.3
WP_099233435.1\|3461206_3461662_+	ArpU family transcriptional regulator	S6AVV9	Thermus_phage	1.6e-72	93.3
WP_099233437.1\|3461759_3462695_+	hypothetical protein	A0A1L2JY39	Aeribacillus_phage	2.8e-18	26.3
WP_099233439.1\|3462721_3463255_+	hypothetical protein	NA	NA	NA	NA
WP_076611651.1\|3463666_3464712_-\|transposase	IS630-like element ISBs2 family transposase	S5VXX4	Leptospira_phage	4.7e-27	27.5
WP_099233441.1\|3465053_3465284_+	hypothetical protein	NA	NA	NA	NA
WP_172437894.1\|3465404_3466682_+	hypothetical protein	NA	NA	NA	NA
WP_099233445.1\|3466674_3467451_+	phosphoadenosine phosphosulfate reductase family protein	NA	NA	NA	NA
WP_099233447.1\|3467544_3468210_+	hypothetical protein	A0A2K9V492	Faecalibacterium_phage	1.5e-23	37.9
WP_099233449.1\|3468225_3469338_+	phosphoadenosine phosphosulfate reductase family protein	A0A2K9V409	Faecalibacterium_phage	2.0e-76	42.0
WP_099233619.1\|3469352_3469874_+	ParB N-terminal domain-containing protein	A0A2K9V467	Faecalibacterium_phage	5.0e-62	68.9
WP_099233621.1\|3469885_3470425_+	hypothetical protein	NA	NA	NA	NA
WP_099233451.1\|3470399_3471794_+\|terminase	phage terminase large subunit	A0A2K9V3I6	Faecalibacterium_phage	5.5e-148	56.3
WP_081157441.1\|3471812_3473261_+\|portal	phage portal protein	A0A2L1IVM1	Streptomyces_phage	7.5e-47	30.8
WP_099233453.1\|3473253_3474120_+\|head	phage head morphogenesis protein	NA	NA	NA	NA
WP_099233455.1\|3474187_3475591_+	structural protein	Q9HH51	Methanothermobacter_phage	2.3e-37	51.9
WP_099233457.1\|3475627_3476545_+\|capsid	phage major capsid protein	V9QJI4	Rhizobium_phage	2.2e-36	37.3
WP_099233459.1\|3476559_3476919_+	hypothetical protein	NA	NA	NA	NA
WP_099233461.1\|3476925_3477348_+	hypothetical protein	NA	NA	NA	NA
WP_099233463.1\|3477353_3477779_+	HK97 gp10 family phage protein	D4P800	Rhodococcus_phage	1.1e-06	43.1
WP_099233465.1\|3477775_3478219_+	hypothetical protein	NA	NA	NA	NA
WP_008880455.1\|3478220_3478433_+	hypothetical protein	NA	NA	NA	NA
WP_008880456.1\|3478444_3479395_+	hypothetical protein	NA	NA	NA	NA
WP_008880457.1\|3479468_3479897_+	hypothetical protein	NA	NA	NA	NA
WP_099233623.1\|3481157_3482720_+	hypothetical protein	Q0H230	Geobacillus_phage	2.1e-18	58.2
WP_099233467.1\|3482716_3483466_+\|tail	phage tail family protein	W8EK66	Geobacillus_phage	6.8e-52	40.0
WP_099233469.1\|3483481_3484546_+	hypothetical protein	W8EIX3	Geobacillus_phage	6.9e-50	37.3
WP_099233470.1\|3484556_3486050_+\|tail	phage tail protein	W8EEW0	Geobacillus_phage	1.3e-139	51.0
WP_011888049.1\|3486046_3486244_+	hypothetical protein	W8ECV6	Geobacillus_phage	5.8e-11	56.5
WP_011888048.1\|3486248_3487046_+	hypothetical protein	W8EBC9	Geobacillus_phage	5.0e-53	43.9
WP_099233472.1\|3487042_3489934_+	glycoside hydrolase	W8EK73	Geobacillus_phage	4.7e-234	43.7
WP_081207181.1\|3489948_3490299_+	hypothetical protein	NA	NA	NA	NA
WP_060476139.1\|3490298_3490484_+	hypothetical protein	NA	NA	NA	NA
WP_060476138.1\|3490502_3490862_+	hypothetical protein	NA	NA	NA	NA
WP_008880469.1\|3490959_3491466_+	hypothetical protein	NA	NA	NA	NA
WP_099233474.1\|3491549_3492236_+	N-acetylmuramoyl-L-alanine amidase	A6XML1	Bacillus_virus	5.6e-61	59.1
WP_099233476.1\|3492333_3492645_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_087959838.1\|3492706_3493875_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.4e-59	42.8
WP_099233478.1\|3494127_3495096_+	restriction endonuclease	NA	NA	NA	NA
WP_099233480.1\|3495129_3496323_-	DNA (cytosine-5-)-methyltransferase	Q6DMX0	Streptococcus_phage	1.3e-134	65.1
WP_099233482.1\|3496889_3498125_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	6.4e-140	62.2
WP_060476135.1\|3498481_3498700_+	hypothetical protein	Q0H253	Geobacillus_phage	5.6e-31	84.3
WP_008881007.1\|3498799_3499462_-	hypothetical protein	D2XR34	Bacillus_phage	9.7e-18	58.0
WP_051358552.1\|3500790_3501240_+	hypothetical protein	S6AVV9	Thermus_phage	4.1e-12	75.0
WP_171355773.1\|3501193_3501352_-	YjcZ family sporulation protein	NA	NA	NA	NA
WP_008880479.1\|3502919_3505697_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_008880480.1\|3505891_3506821_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_060475996.1\|3506822_3507668_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_021292746.1\|3508051_3509221_+\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	3.3e-21	26.3
WP_087959814.1\|3509472_3510642_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	2.5e-24	25.1
WP_081157417.1\|3511205_3512321_+	long-chain fatty acid--CoA ligase	NA	NA	NA	NA
WP_008880483.1\|3512317_3513769_+	acyl-CoA reductase	NA	NA	NA	NA
WP_060475995.1\|3513783_3514530_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-38	39.1
WP_008880485.1\|3514526_3515282_+	ABC transporter permease	NA	NA	NA	NA
WP_008880486.1\|3515278_3516310_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008880487.1\|3516322_3517093_+	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_060475993.1\|3517272_3517590_+	hypothetical protein	NA	NA	NA	NA
WP_099233484.1\|3517689_3518931_-	aminopeptidase	NA	NA	NA	NA
WP_060475991.1\|3519214_3520651_+	sodium/proline symporter	NA	NA	NA	NA
WP_011887644.1\|3521118_3521622_+	DoxX family protein	NA	NA	NA	NA
WP_171355512.1\|3522353_3522665_+	autorepressor SdpR family transcription factor	NA	NA	NA	NA
WP_008880493.1\|3522661_3523318_+	SdpI family protein	NA	NA	NA	NA
WP_008880494.1\|3523332_3524115_+\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
3528771:3528787	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP017691

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP017690

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection