CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP024489	Klebsiella pneumoniae strain INF249 chromosome, complete genome	2 crisprs	csa3,cas3,DEDDh,DinG,WYL,RT	1	10
NZ_CP024494	Klebsiella pneumoniae strain INF249 plasmid unnamed5, complete sequence	0 crisprs	NA	0	0
NZ_CP024490	Klebsiella pneumoniae strain INF249 plasmid unnamed1, complete sequence	0 crisprs	RT	0	1
NZ_CP024492	Klebsiella pneumoniae strain INF249 plasmid unnamed3, complete sequence	0 crisprs	NA	0	0
NZ_CP024491	Klebsiella pneumoniae strain INF249 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0
NZ_CP024495	Klebsiella pneumoniae strain INF249 plasmid unnamed6, complete sequence	0 crisprs	NA	0	0
NZ_CP024493	Klebsiella pneumoniae strain INF249 plasmid unnamed4, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

23581 : 36253

Escherichia_phage(33.33%)

integrase

attL 22009:22020|attR 27144:27155

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
22009:22020	attL	NA	NA	NA	NA
WP_029497485.1\|23581_24361_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	7.1e-52	92.0
WP_000764642.1\|24418_24676_-	hypothetical protein	NA	NA	NA	NA
WP_012539983.1\|25551_26307_+	replication initiation protein RepE	I3WF20	Macacine_betaherpesvirus	1.7e-135	95.2
WP_000368714.1\|27072_28278_+	ParA family protein	A0A077SL49	Escherichia_phage	2.4e-163	69.6
27144:27155	attR	NA	NA	NA	NA
WP_086523286.1\|28274_29252_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	1.4e-86	53.8
WP_029497486.1\|29333_30605_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	2.2e-151	62.8
WP_015632467.1\|30604_31036_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	7.2e-30	53.7
WP_004152765.1\|31444_32929_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_001568038.1\|33177_34149_+	hypothetical protein	A0A222YXF2	Escherichia_phage	1.1e-73	46.8
WP_050888056.1\|34151_34823_+	Mediator of plasmid stability	NA	NA	NA	NA
WP_001568040.1\|34884_35115_+	hypothetical protein	NA	NA	NA	NA
WP_001568041.1\|35551_36253_+	DNA methylase	A0A2I7RE86	Vibrio_phage	1.6e-26	36.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP024489

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP024489_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP024489_1

731506-731671

Orphan

Consensus_repeat	Method
GAGTCCGGAATCCGGACTCAGTC	CRT

3 spacers

The CRISPR arrays of NZ_CP024489_1

>merge|NZ_CP024489|1|731506-731671|CRT
GAGTCCGGAATCCGGACTCAGTCAAAAAAGCACCAAAAACATCCCGGAATCACTGAGTCCGGAAAACGGACTCAGTACCCCGTCAGTGGATAAAACACAGAGTCCGGAATCAGGACTCAGTCTGAAATCAACGAGTTACACCGGAGTCCGGAATCCGGACTGTAAC

>NZ_CP024489|1|1|731506-731671|CRT
GAGTCCGGAATCCGGACTCAGTC	AAAAAAGCACCAAAAACATCCCGGAATCACT
GAGTCCGGAAAACGGACTCAGTA	CCCCGTCAGTGGATAAAACACA
GAGTCCGGAATCAGGACTCAGTC	TGAAATCAACGAGTTACACCG
GAGTCCGGAATCCGGACTGTAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024489.1\|WP_007372584.1\|736951_737236_+\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|226860
NZ_CP024489.1\|WP_071838928.1\|724637_724823_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024489.1\|WP_007372575.1\|729950_730550_+\|DUF2857-domain-containing-protein	unknown	unknown	gnl\|CDD\|378591
NZ_CP024489.1\|WP_007372572.1\|727176_728883_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|213858
NZ_CP024489.1\|WP_013095151.1\|732343_733066_+\|TIGR03761-family-integrating-conjugative-element-protein	unknown	unknown	gnl\|CDD\|274771
NZ_CP024489.1\|WP_013095145.1\|724938_725823_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NZ_CP024489.1\|WP_044159002.1\|733083_735096_+\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP024489.1\|WP_072057195.1\|741434_742649_+\|type-4b-pilus-protein-PilO2	unknown	unknown	gnl\|CDD\|369114
NZ_CP024489.1\|WP_007372573.1\|728875_729133_+\|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|222775
NZ_CP024489.1\|WP_007372587.1\|739229_739673_+\|type-IV-pilus-biogenesis-protein-PilM	unknown	unknown	gnl\|CDD\|369356
NZ_CP024489.1\|WP_013095147.1\|729122_729866_+\|DUF2786-domain-containing-protein	unknown	unknown	gnl\|CDD\|378525
NZ_CP024489.1\|WP_007372583.1\|736295_736796_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|236362
NZ_CP024489.1\|WP_007372582.1\|735728_736220_+\|DUF3577-domain-containing-protein	unknown	unknown	gnl\|CDD\|371899
NZ_CP024489.1\|WP_013095157.1\|739692_741366_+\|PilN-family-type-IVB-pilus-formation-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274177
NZ_CP024489.1\|WP_087473107.1\|724311_724497_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024489.1\|WP_085707915.1\|724474_724660_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024489.1\|WP_044159004.1\|737226_737709_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP024489.1\|WP_044158999.1\|725815_727180_+\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NZ_CP024489.1\|WP_013095156.1\|737941_739228_+\|pilus-biogenesis-protein-PilL	unknown	unknown	gnl\|CDD\|163460
NZ_CP024489.1\|WP_013095148.1\|730549_730780_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP024489.1\|WP_007372584.1\|736951_737236_+\|DUF1778-domain-containing-protein	gnl\|CDD\|226860	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown].	5.96838e-20
NZ_CP024489.1\|WP_013095157.1\|739692_741366_+\|PilN-family-type-IVB-pilus-formation-outer-membrane-protein	gnl\|CDD\|274177	TIGR02520, putative_Type_IV_pilus_protein, type IVB pilus formation outer membrane protein, R64 PilN family. Several related protein families encode outer membrane pore proteins for type II secretion, type III secretion, and type IV pilus formation. This protein family appears to encode a secretin for pilus formation, although it is quite different from PilQ. Members include the PilN lipoprotein of the plasmid R64 thin pilus, a type IV pilus. Scoring between the trusted and noise cutoffs are examples of bundle-forming pilus B (bfpB). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	1.02385e-122
NZ_CP024489.1\|WP_007372575.1\|729950_730550_+\|DUF2857-domain-containing-protein	gnl\|CDD\|378591	pfam11198, DUF2857, Protein of unknown function (DUF2857). This is a bacterial family of uncharacterized proteins.	3.09237e-67
NZ_CP024489.1\|WP_007372572.1\|727176_728883_+\|hypothetical-protein	gnl\|CDD\|213858	TIGR03764, ICE_PFGI_1_parB, integrating conjugative element, PFGI_1 class, ParB family protein. Members of this protein family carry the ParB-type nuclease domain and are found in integrating conjugative elements (ICE) in the same class as PFGI-1 of Pseudomonas fluorescens Pf-5.	2.01578e-142
NZ_CP024489.1\|WP_013095151.1\|732343_733066_+\|TIGR03761-family-integrating-conjugative-element-protein	gnl\|CDD\|274771	TIGR03761, ICE_PFL4669, integrating conjugative element protein, PFL_4669 family. Members of this protein family, such as PFL4669, are found in integrating conjugative elements (ICE) of the PFGI-1 class as in Pseudomonas fluorescens.	2.75731e-90
NZ_CP024489.1\|WP_013095145.1\|724938_725823_+\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	5.15896e-22
NZ_CP024489.1\|WP_044159002.1\|733083_735096_+\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP024489.1\|WP_072057195.1\|741434_742649_+\|type-4b-pilus-protein-PilO2	gnl\|CDD\|369114	pfam06864, PAP_PilO, Pilin accessory protein (PilO). This family consists of several enterobacterial PilO proteins. The function of PilO is unknown although it has been suggested that it is a cytoplasmic protein in the absence of other Pil proteins, but PilO protein is translocated to the outer membrane in the presence of other Pil proteins. Alternatively, PilO protein may form a complex with other Pil protein(s). PilO has been predicted to function as a component of the pilin transport apparatus and thin-pilus basal body. This family does not seem to be related to pfam04350.	2.42601e-54
NZ_CP024489.1\|WP_007372573.1\|728875_729133_+\|TraR/DksA-family-transcriptional-regulator	gnl\|CDD\|222775	PHA00080, PHA00080, DksA-like zinc finger domain containing protein.	6.17926e-12
NZ_CP024489.1\|WP_007372587.1\|739229_739673_+\|type-IV-pilus-biogenesis-protein-PilM	gnl\|CDD\|369356	pfam07419, PilM, PilM. This family contains the bacterial protein PilM (approximately 150 residues long). PilM is an inner membrane protein that has been predicted to function as a component of the pilin transport apparatus and thin-pilus basal body.	1.81612e-24
NZ_CP024489.1\|WP_013095147.1\|729122_729866_+\|DUF2786-domain-containing-protein	gnl\|CDD\|378525	pfam10979, DUF2786, Protein of unknown function (DUF2786). This family of proteins has no known function.	3.66896e-10
NZ_CP024489.1\|WP_007372583.1\|736295_736796_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|236362	PRK09010, PRK09010, single-stranded DNA-binding protein; Provisional.	5.62478e-91
NZ_CP024489.1\|WP_007372582.1\|735728_736220_+\|DUF3577-domain-containing-protein	gnl\|CDD\|371899	pfam12101, DUF3577, Protein of unknown function (DUF3577). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 143 to 307 amino acids in length.	1.92784e-61
NZ_CP024489.1\|WP_044159004.1\|737226_737709_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.00414362
NZ_CP024489.1\|WP_044158999.1\|725815_727180_+\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP024489.1\|WP_013095156.1\|737941_739228_+\|pilus-biogenesis-protein-PilL	gnl\|CDD\|163460	TIGR03748, conj_PilL, conjugative transfer region protein, TIGR03748 family. This model describes the conserved N-terminal region of a variable length protein family associated with laterally transfered regions flanked by markers of conjugative plasmid integration and/or transposition. Most members of the family have the lipoprotein signal peptide motif. A member of the family from a pathogenicity island in Salmonella enterica serovar Dublin strain was designated PilL for nomenclature consistency with a neighboring gene for the pilin structural protein PilS. However, the species distribution of this protein family tracks much better with markers of conjugal transfer than with markers of PilS-like pilin structure. [Mobile and extrachromosomal element functions, Plasmid functions].	7.38231e-55

>NZ_CP024489.1|WP_013095148.1|730549_730780_+|hypothetical-protein
MEMGDFSPRQQVSPAVRRRAQQLFRAACGGQKVFRRLTMNGYLKIDVGPFWRILSKDGCRQWWLMDHETYNREIRR
>NZ_CP024489.1|WP_007372575.1|729950_730550_+|DUF2857-domain-containing-protein
MSQHNLSQATTAILSSLLMDVKNGNIRRCESLGMSVEEIRALSHLSLDELHYLSQSHVSVLDVTLNHENFWLMLNQARNEQKRFMMIDRALELGGSMELIDRYFGLSPSEVSARRRLMGIESRQGRTQALTEPQDAALWAEWKAAGLSSPDSHQALEAMMLAAEQLGLSLTAVWSRVCQWCREANAAGRRAEIPVRKEA
>NZ_CP024489.1|WP_013095147.1|729122_729866_+|DUF2786-domain-containing-protein
MSDNAKITARIRRLMALGTRNSNPHEAARAVALAQRLMQRHGLTPDMLSLSDVSESVCFSLTSDAEKVPAWLSSLATVVCMATGCRCWFGWHVHVSPQGVSSVRRSLHFYGFSERPEVALYIYTVLQRQLRAATDAHMSGYRTRRILLRTRRRRADQFREGWVSGVWQVLQSFAPSGEENAVLQRWLVRRHAGEPLEDMAVRSAGKCRGDRTARVAGFFAGRDIDLHHGLSGAQASRQITAGGHAHD
>NZ_CP024489.1|WP_007372573.1|728875_729133_+|TraR/DksA-family-transcriptional-regulator
MSDDLNDEMAQASTALFIQHGIDAIRAKVNSATPSKAFCECCGAAIPVARQLAVPGVELCAGCQEVKEMKNRHRADGGRGMRHVG
>NZ_CP024489.1|WP_007372572.1|727176_728883_+|hypothetical-protein
MSNVRNLNLGAAMLQRGKTPAQGDAVPAAVPLPVSEMAMVLTLDQLRPNPDNPRKSRNPHFDEIKASIRACGLVQVPKVTRDPDGEDVYIFSDGGNTRYQILCELWQETGDERFYRVHTIFKPWPGRLKCLVGHLAENEVRGDLSYIDKAFGVHSARAIQEELMGRPVTLRELSDLLNLEGYPIDYSTISRMEDTIKYLWPCIPNLLNSGLARLQVLSLLRIRSQAGKVWSQFAHESSPQCSFDQVFEASCQGFDDPDSYAYETFRDEFIGQLVKALPHPSLNYDRWMIELDPREQKRREQFGEPPPLPVLTPPQEKAAGREPPEPQVTVLPPDTASETPVTGLRSGTLTTPGRPEPAPELPADAELPVNALMTAGSEPRREVQNDLFGGRPVISGETADPDSISLPDFSPDTLMSAFGEENASPAASVSSVAFAATGLEPVSDIWHIPALQDDIEHLQDMAYRLVFEIAEAMGCADNVREDKNPQSAGFAVSETGSEFVLFLAGLSGSLPNRQFNMFMFCLNFFGSQSPADMAVFDDITVVKTMRLIRVIRRLRELQRLAAKGGENV
>NZ_CP024489.1|WP_044158999.1|725815_727180_+|replicative-DNA-helicase
MSDDRRNIPGIYSPDAEQSVIGGLMLDNDRWDEVALRLSADDFFQKVHKVIYQEMTRLVAAGKPLDLITLSESIESRGKDALEQLGGFAYLAELSKNTPSAANIVAYCDIVARTSRARQLASIGAEITESVRTPGTDIDRVMETAEQKITRLAERAEPEQGVTLLEGMERLLPELERRCNVPDGITGTPTGFEELDAMTSGLQAGDLVLIAARPSMGKTALLISLLLNSLMKKSGSKGQLYSMEQPTEQILMRMLASLGSIDLTHLKSGLMDDEDWARATDASALLMGDLNDSLIIDDTGSLTPAMLRIRARRNARRYGHPSIIGLDYLQLMRCPDQENRTQEIAEISRSLKALAKEMMCPVVALSQLNRQLESRADKRPNNGDLRDSGALEQDADVIVFIYRDEVYHENTEDKGIAEIIISKQRQGPTGTIRLQYEGRFTRFSDVAGRPGRSA
>NZ_CP024489.1|WP_013095145.1|724938_725823_+|ParA-family-protein
MHSKTKVVPVVSTKGGEGKSTQAANLGGFLADAGIKTLIIDGDHAQPTASSIYPLAYEAPCGLYELLMQTVDLSKAENIISRTTIDNLDVIVSNDPRNLLPTYMLNVPDGRVRLRNALSNQVFSQYDVILIDSQGSRSVMSELIILAATGEMIGMVKPVLPDVREFMRGTVALMEELIPYMAFGISLPRIHMLVNCMDYTLLAKTTVEQAENIIVSGDYSQHADKIVIDMLQTRIYDLDVYKQGHAAGQPVHRLEKKTSRKSDSAFDSMHGLACELFPEWVSLFDTLAKGGERV
>NZ_CP024489.1|WP_071838928.1|724637_724823_+|hypothetical-protein
MWAGSLNSGARTRTNAAGVEQRACRAGPEGVSRCAANNRTQFDGESGYRKAKTRLLGGFFK
>NZ_CP024489.1|WP_085707915.1|724474_724660_+|hypothetical-protein
MWAGSLNSGARTRTNAAGVEQRACRAGPEGVSRCAANNRTQFDGESGRRKAKTRLVGGFFK
>NZ_CP024489.1|WP_087473107.1|724311_724497_+|hypothetical-protein
MEVRCYEFGARIRTNAAGVEQRACRAGPEGVSRCAANNRTQFDGESGRRKAKTRLVGGFFK
>NZ_CP024489.1|WP_013095151.1|732343_733066_+|TIGR03761-family-integrating-conjugative-element-protein
MADKQVTKTGSLQSEMTIALHTNYAIGLWLGRKREKQEDNTPVKHGIIGMPQFFVRATLINQDSLNNNPWADEAMYRLEEKLRSATETMTGLIKQLDEEMSMLPAGITLTEVTSVEPLDIHVFTRTPLGYRCVFLLVGFDQFAKKVLQASHYGLITRNGRDNYLSEGGRLLRQIYGTVLSYRRVDATRLDAAENNEVWQKACQEAGEPDRAVLLGEKRSAFSPPVNEASVNLLRLRYQTV
>NZ_CP024489.1|WP_044159002.1|733083_735096_+|DNA-topoisomerase-III
MRLFICEKPSQGRDLAGVLGATRRGDGFLTGSGVTVTWAVGHLLETAPPEAYGQQYGKPWSLSALPILPAPWRVVVKKETQDQFKVIERLLRQVDDVVIATDADREGEVIARELLEYCRWEGPVQRLWLSALDELSIRAALQDLRPGQATLGMYHAGLGRARADWLIGMNLSRLYTLRAAESGFDGVVSVGRVQTPTLALVVRRDREIAAFVPKPFWQVKALISAGDLTFPAQWVPAKVYTDEEKRCVHQNIAQQVAQLCRQTGHAVVTECDTKREKAAAPLAFSLGSLQQACGRLWDMSPQQVLDTAQSLYEKHKATTYPRTDCGYLPESMREEISGVLDAIGRTDPECAPVLARLDRTFVSRIWNDKKITAHHGIIPTRNAFQLSALTETERNVYMLIRRNYLAQFLPLHESDFTRLQFDTGGQLFRATGRTEVIKGWKVLFENAGDNEVDDGDEADIALPPLAQNDRCAVTGAEVVQLMTRPPAHYTFATLIGAMMNAAAFVTDVALRKVLKDNAGLGTEATRAGIVEQLLNRHFIVRKGSKIMATELGADVIDALPPQLTEPGMTALWEQALDEVAAGRMSLDDFLQRQTGWTRNLVSQGTQQQVRIRVPPTPACPLCGGKTRLRRGEKGEFWSCQRWPECKGVINIGGTRKKRPRRAKSPESKKN
>NZ_CP024489.1|WP_007372582.1|735728_736220_+|DUF3577-domain-containing-protein
MTATTTTPASTGSASASQKKEFFNLNVNGIGYLSSIRRVQGGNGEFTCAVINALTGPTDNASYTRFDVTIAGAETTKLINRCQKAVDEEEKVLIGFVLSGLKADVFTLQTGDHAGESRPSLKARLIKVEFIKKGQDVVYQAPNASQTPESGSSAQKEYDPNSF
>NZ_CP024489.1|WP_007372583.1|736295_736796_+|single-stranded-DNA-binding-protein
MSARGVNKVILVGHLGQDPEVRYMPDSTAVTTLSVATSETWRDKQTGENRENTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLRTRKWTDTNGIERWTTEVRVGVNGTMQMLGGGRNNSTNTSGNNAQSGQQGGWGQPQQPQQTPSAPQNPQNEPPMDFDDDIPF
>NZ_CP024489.1|WP_007372584.1|736951_737236_+|DUF1778-domain-containing-protein
MQTPVRKSVRDKQINIRATDEERAVIDYAASLVNKNRTDFIIERAVHEAQNIILDQRVFVLDDARYQAFIRQLEAPVQNVEGRQRLMDVKPEWK
>NZ_CP024489.1|WP_044159004.1|737226_737709_+|GNAT-family-N-acetyltransferase
MEINVTAPALLTEEHVLHSFDCGNAVLDDWLRRRALKNQHLNASRTFVICPEGTACVVGYYSLATGSVSHVDLSRSLRQNMPDPVPVVLLGRLAVDVSTQGNNFGKWLLNDAVMRVSNLADQVGIKAIMVHAIDERAKAFYEYFGFVQSPVAANTLFYKI
>NZ_CP024489.1|WP_013095156.1|737941_739228_+|pilus-biogenesis-protein-PilL
MAVPSRRVATGAALLACSVIQAGCSSAVSDPAPFANGRYQQPTRFDDIYRNRAPDVVRYDRYTLVSTRPDDAQRDPLNQIVDITMPAQLVKTVGEGFRYLLLESGYSLCSATTSAFSELLSRPLPAVQRDIGPVRLSEALQIVAGPAWRLKVDDVNREICFELRDQYRSFAAPLPAPVSLVSQHAPVSLPPVIQPARTGGAAGTVNAVPRNPFTGDTSINSTPGTLQKPVLTAQNQSVPSPVLTVAKTPAAQKSAALSPAGRPPVPPPAAAPKAASSQKTPVTAVHPVTVQPATVNAARQTVPVRPVTSLPPAPPVSGQTASSYIPGAPVTPQPVGQTWRAEPGSTLKETLTGWASKATCSNGGNWVVIWPVSLDYRIDAPLVFHGNFESVLVQVFDLYRKAEKPLFAEANRIQCLISVSDTPTGGGH
>NZ_CP024489.1|WP_007372587.1|739229_739673_+|type-IV-pilus-biogenesis-protein-PilM
MGYALPVFVFCLVIALMAGDAQRHSAEHVRLSLQQTLPDQLATDMLRTADAVNNWRHGRTVADGTVTPAQAGIVPAPDSRIQTVIQGGRLWVWVPATDGVYAALRTQSVTSALALTVSGGRLRMADGTDMNLSLPSGVTEGSIVYLN
>NZ_CP024489.1|WP_013095157.1|739692_741366_+|PilN-family-type-IVB-pilus-formation-outer-membrane-protein
MPRLPFCLTALVAALALSSCSLNEISKMDKEASGQADTAQRVLQSRQTLTQPTVVWSDKPWVNLQPVTPVISTPDEKNLPACQITINRPEGISLPELGQRITALCGIRVSITPDAFAALSSISTGSVVTSQMNGQLPAPDDNGRVPLSQMGTTSAQPVSVQSSPSLIRGLKYQGDIRGLLDMAASGLGLSWRIDSSGVYFYQQDTRTFQLVILNTKVNSSASINSGSGNQLGSGGGTSGGTTGDISSNQKTDYGMNSDLYDDIKKTVEQMVTPKSGRFWLSSATGTLSVTDTPDVLNRIGRYIEYQNKVLSRQVQLNIQIVSVNQTRNEQMGLDWGLVYKSLQNVGASLTGSMANASSSAASAGISILDTASGNAAKFSGSSLLIHALSEQGNVSMALNQTDPTANLTPVAYQLSKSTGMLTSSSSTATANVGVTSTMTTTNVTTGLFMTMLPFIQENGDVQLQFAFSYTSPPDIKSFVSRDGNTRNDTADTSTEGLARKVNLRSGQTLVLTGSEQQNVSADKQGTFTPGNFILGGGQTGSRGRTTLVIMITPVLLR
>NZ_CP024489.1|WP_072057195.1|741434_742649_+|type-4b-pilus-protein-PilO2
MAGLHWAPQHSVLSVRLRGRASPDTHCVTAGRGSASMAGVVSPGRVRHRLYALAVAFQLSEGGNAWGIYRLSRDEDLWVFFAASGGQLSVMGDVTGTRAFIESAAQNFLRFNDADAPGLRCAATAEDGRDATTLTDRLSGAQLRRCRLRKRLAPMSLILPAVVLTLATAAGVYWHDTVQQQADRDKAMEASRSRVAPKNDKPALPARAPHPWASQPPVSVLLSNCWLTREPVFASVAGWRFTDGECVPEGLRLRFVATPGSTVEDFSRRARELLGHAAVFNLQEGGKNGDVFIPFRKYLAGEYTDEALPGAEAQLMRFISHLQRRNLDVKFTEVKPPAVAPGQEKNTPVQDWREFTFSVSSRLQPERLLQDFDAAGLRLTSVSITMSPQGQFGYTMKGSIYAQN

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Crispr_ID: NZ_CP024489_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP024489_2

4461864-4461958

Orphan

Consensus_repeat	Method
ACTATGGTTTTTATGGTTTTTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP024489_2

>merge|NZ_CP024489|2|4461864-4461958|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATGGTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATGACTGTGGTTTTTATGGTTTTTATT

>NZ_CP024489|2|1|4461864-4461958|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATG	GTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATG
ACTGTGGTTTTTATGGTTTTTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024489.1\|WP_032103829.1\|4465516_4467865_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP024489.1\|WP_002888353.1\|4452643_4453339_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP024489.1\|WP_002888323.1\|4471021_4471399_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP024489.1\|WP_002888337.1\|4463714_4464413_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP024489.1\|WP_002888345.1\|4460410_4461775_-\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP024489.1\|WP_004145972.1\|4448100_4448946_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP024489.1\|WP_021441192.1\|4451003_4452506_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP024489.1\|WP_023279864.1\|4449283_4450993_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP024489.1\|WP_004192048.1\|4462099_4463725_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP024489.1\|WP_002888327.1\|4469211_4470201_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP024489.1\|WP_002888321.1\|4471403_4472252_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP024489.1\|WP_032428530.1\|4456050_4458957_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP024489.1\|WP_021441191.1\|4453505_4455863_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP024489.1\|WP_021441189.1\|4459691_4460231_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP024489.1\|WP_002888348.1\|4458969_4459629_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP024489.1\|WP_002888373.1\|4447204_4447972_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP024489.1\|WP_002888324.1\|4470197_4471019_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP024489.1\|WP_002888329.1\|4467919_4469206_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP024489.1\|WP_002888332.1\|4464445_4465273_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP024489.1\|WP_002888320.1\|4472504_4472984_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714

Protein	Function_ID	Function_description	E-value
NZ_CP024489.1\|WP_032103829.1\|4465516_4467865_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP024489.1\|WP_002888353.1\|4452643_4453339_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP024489.1\|WP_002888323.1\|4471021_4471399_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
NZ_CP024489.1\|WP_002888337.1\|4463714_4464413_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	5.03078e-66
NZ_CP024489.1\|WP_002888345.1\|4460410_4461775_-\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
NZ_CP024489.1\|WP_004145972.1\|4448100_4448946_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP024489.1\|WP_021441192.1\|4451003_4452506_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP024489.1\|WP_023279864.1\|4449283_4450993_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP024489.1\|WP_004192048.1\|4462099_4463725_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	7.63459e-173
NZ_CP024489.1\|WP_002888327.1\|4469211_4470201_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP024489.1\|WP_002888321.1\|4471403_4472252_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP024489.1\|WP_032428530.1\|4456050_4458957_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP024489.1\|WP_021441191.1\|4453505_4455863_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP024489.1\|WP_021441189.1\|4459691_4460231_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	6.20047e-83
NZ_CP024489.1\|WP_002888348.1\|4458969_4459629_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
NZ_CP024489.1\|WP_002888373.1\|4447204_4447972_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP024489.1\|WP_002888324.1\|4470197_4471019_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
NZ_CP024489.1\|WP_002888329.1\|4467919_4469206_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP024489.1\|WP_002888332.1\|4464445_4465273_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
NZ_CP024489.1\|WP_002888320.1\|4472504_4472984_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127

>NZ_CP024489.1|WP_002888345.1|4460410_4461775_-|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP024489.1|WP_021441189.1|4459691_4460231_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQAGLISRQAQGEAMRRCLLCDEPAHACARSRRHDTGLVVARVEQMIDAWFARD
>NZ_CP024489.1|WP_002888348.1|4458969_4459629_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP024489.1|WP_032428530.1|4456050_4458957_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESTDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAAIESKRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP024489.1|WP_021441191.1|4453505_4455863_+|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSDVNAWWSQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRTQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP024489.1|WP_002888353.1|4452643_4453339_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP024489.1|WP_021441192.1|4451003_4452506_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISNGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATAEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP024489.1|WP_023279864.1|4449283_4450993_+|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQTVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYEDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSQAALTH
>NZ_CP024489.1|WP_004145972.1|4448100_4448946_-|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVRDACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP024489.1|WP_002888373.1|4447204_4447972_-|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR
>NZ_CP024489.1|WP_004192048.1|4462099_4463725_+|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEVHDAS
>NZ_CP024489.1|WP_002888337.1|4463714_4464413_+|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSDREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP024489.1|WP_002888332.1|4464445_4465273_-|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP024489.1|WP_032103829.1|4465516_4467865_+|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSNTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP024489.1|WP_002888329.1|4467919_4469206_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP024489.1|WP_002888327.1|4469211_4470201_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP024489.1|WP_002888324.1|4470197_4471019_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP024489.1|WP_002888323.1|4471021_4471399_+|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP024489.1|WP_002888321.1|4471403_4472252_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP024489.1|WP_002888320.1|4472504_4472984_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP024489_1	1.1\|731529\|31\|NZ_CP024489\|CRT	731529-731559	31	LR135896	uncultured phage genomic DNA containing rbcL region region	68325-68355	5	0.839

1. spacer 1.1|731529|31|NZ_CP024489|CRT matches to LR135896 (uncultured phage genomic DNA containing rbcL region region) position: , mismatch: 5, identity: 0.839

aaaaaagcaccaaaaacatcccggaa-tcact	CRISPR spacer
agaaaagcacaaaaaacaacccggaagtcaa-	Protospacer
*.******** ******* ******* ***

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

780379 : 787503

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013095191.1\|780379_781102_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	1.8e-97	73.0
WP_047028317.1\|781400_781898_-	phosphatase	NA	NA	NA	NA
WP_007372635.1\|782037_782547_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	6.5e-22	37.8
WP_007372636.1\|782619_783048_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	1.8e-49	70.7
WP_013095195.1\|783105_784395_-	arsenical efflux pump membrane protein ArsB	A0A2H4J144	uncultured_Caudovirales_phage	3.3e-171	72.5
WP_013095196.1\|784435_786202_-	arsenical pump-driving ATPase	NA	NA	NA	NA
WP_044158970.1\|786225_786591_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_013095198.1\|786613_787093_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	1.8e-34	51.3
WP_013095199.1\|787149_787503_-	metalloregulator ArsR/SmtB family transcription factor	A0A2H4J145	uncultured_Caudovirales_phage	5.9e-22	47.2

DBSCAN-SWA_2

1737000 : 1743905

Planktothrix_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032429748.1\|1737000_1737864_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5
WP_047669696.1\|1737874_1738648_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.1e-26	36.7
WP_002912636.1\|1738888_1739782_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
WP_004144192.1\|1740027_1741389_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.8e-207	94.8
WP_004175198.1\|1741707_1742430_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
WP_004149058.1\|1742426_1743905_-	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	8.5e-30	28.3

DBSCAN-SWA_3

2704749 : 2711179

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021440085.1\|2704749_2705838_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	5.2e-210	99.7
WP_004176262.1\|2705924_2706185_-	hypothetical protein	A0A077SK33	Escherichia_phage	5.4e-41	98.8
WP_021440083.1\|2706476_2707343_+	class A beta-lactamase SHV-187	A0A077SL40	Escherichia_phage	1.7e-155	99.6
WP_002210513.1\|2707363_2708125_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004224682.1\|2709300_2710566_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	7.8e-234	99.8
WP_002210516.1\|2710558_2711179_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_4

2905561 : 2975334

Klebsiella_phage(42.0%)

protease,tail,portal,plate,holin,integrase,head,capsid,terminase

attL 2902842:2902856|attR 2974685:2974699

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2902842:2902856	attL	NA	NA	NA	NA
WP_004176418.1\|2905561_2906647_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_021440010.1\|2906610_2908365_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004183804.1\|2908443_2910036_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_021440009.1\|2910032_2913482_-	type VI secretion protein VasK	NA	NA	NA	NA
WP_021440008.1\|2913471_2914653_-	hypothetical protein	NA	NA	NA	NA
WP_023302025.1\|2914601_2914859_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_064185090.1\|2914901_2917301_-	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_023302028.1\|2917288_2917819_-	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_021440005.1\|2917843_2918620_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_023302029.1\|2918623_2921002_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.4e-18	33.0
WP_047670330.1\|2920994_2923637_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	4.0e-99	33.5
WP_002902160.1\|2923901_2924393_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_021440002.1\|2924397_2926104_-	OmpA family protein	NA	NA	NA	NA
WP_004176431.1\|2926100_2926790_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004197477.1\|2926786_2928127_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_021440001.1\|2928139_2929684_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004176434.1\|2929726_2930218_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002902136.1\|2931063_2931312_+	DinI-like family protein	S5MQI1	Escherichia_phage	1.4e-25	70.4
WP_074194671.1\|2932362_2932785_-	hypothetical protein	K7P834	Enterobacteria_phage	1.2e-24	43.8
WP_064185091.1\|2932862_2933411_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	5.4e-91	95.6
WP_099725673.1\|2934297_2935590_+	hypothetical protein	B5TAB2	Burkholderia_phage	1.4e-68	37.2
WP_085841178.1\|2935590_2936340_+	hypothetical protein	NA	NA	NA	NA
WP_064185172.1\|2936471_2937071_-	hypothetical protein	NA	NA	NA	NA
WP_064185171.1\|2937312_2939259_-	hypothetical protein	A0A286S1P0	Klebsiella_phage	7.2e-53	85.2
WP_099725604.1\|2939333_2942411_-	kinase	A0A286S259	Klebsiella_phage	0.0e+00	62.3
WP_023341479.1\|2942407_2942788_-	hypothetical protein	A0A286S2A6	Klebsiella_phage	8.5e-59	81.7
WP_004864228.1\|2942800_2943277_-	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	4.8e-51	65.8
WP_004177132.1\|2943263_2943737_-	hypothetical protein	A0A286S298	Klebsiella_phage	1.4e-55	62.1
WP_099725605.1\|2943757_2947144_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	9.5e-303	57.7
WP_016530182.1\|2947204_2947438_-	hypothetical protein	K7PH16	Enterobacteria_phage	1.9e-08	47.2
WP_099725606.1\|2947511_2947817_-	DUF4035 domain-containing protein	Q9MCS5	Enterobacteria_phage	4.7e-28	64.6
WP_021313622.1\|2947819_2948224_-\|tail	phage tail protein	K7PKV6	Enterobacterial_phage	8.5e-33	57.7
WP_021313623.1\|2948254_2948959_-	immunoglobulin domain-containing protein	K7PHL2	Enterobacterial_phage	2.5e-80	66.9
WP_016530186.1\|2949015_2949363_-	DUF3168 domain-containing protein	K7PKL6	Enterobacterial_phage	2.8e-32	63.7
WP_064185142.1\|2949359_2949809_-	HK97 gp10 family phage protein	Q9MCS9	Enterobacteria_phage	1.5e-62	81.9
WP_064185143.1\|2949805_2950144_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	1.0e-39	70.5
WP_032415158.1\|2950155_2950482_-\|head,tail	phage gp6-like head-tail connector protein	K7PKT4	Enterobacteria_phage	2.8e-42	70.4
WP_032442228.1\|2950481_2950715_-	hypothetical protein	A0A1P8DTJ1	Proteus_phage	1.5e-10	68.1
WP_064160189.1\|2950757_2951975_-\|capsid	phage major capsid protein	K7PM57	Enterobacteria_phage	1.9e-197	88.1
WP_023317649.1\|2951984_2952833_-\|protease	Clp protease ClpP	K7PH05	Enterobacteria_phage	3.0e-136	89.6
WP_004177155.1\|2952846_2954154_-\|portal	phage portal protein	K7PJU5	Enterobacteria_phage	4.9e-215	85.7
WP_023342855.1\|2955849_2956314_-\|terminase	phage terminase small subunit P27 family	Q9B019	Phage_GMSE-1	1.7e-48	61.4
WP_023342856.1\|2956496_2956838_-	HNH endonuclease	K7P7P4	Enterobacteria_phage	2.3e-47	73.9
WP_004177166.1\|2956893_2957139_-	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	4.7e-18	63.0
WP_004177168.1\|2957536_2957737_-	hypothetical protein	A0A1L6Z528	Klebsiella_phage	3.4e-19	75.0
WP_004177172.1\|2958047_2958320_-	hypothetical protein	NA	NA	NA	NA
WP_004177174.1\|2958452_2958737_+	hypothetical protein	NA	NA	NA	NA
WP_032409976.1\|2958827_2959022_-	hypothetical protein	A0A286SGR9	Klebsiella_phage	6.9e-25	89.1
WP_004177178.1\|2958972_2959248_-	hypothetical protein	A0A286N2Q8	Klebsiella_phage	8.4e-08	96.7
WP_004177180.1\|2959244_2959592_-	hypothetical protein	A0A286N2Q7	Klebsiella_phage	1.9e-41	83.5
WP_004177182.1\|2959588_2960128_-	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	2.0e-101	98.3
WP_031280382.1\|2960124_2960424_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	2.9e-46	99.0
WP_004177186.1\|2960709_2960955_-	hypothetical protein	NA	NA	NA	NA
WP_064185145.1\|2961150_2961966_-	molecular chaperone	A0A286N2Q2	Klebsiella_phage	9.5e-108	74.2
WP_064185146.1\|2961962_2962280_-	hypothetical protein	NA	NA	NA	NA
WP_064185147.1\|2962282_2964154_-	AAA family ATPase	K7PK08	Enterobacteria_phage	1.0e-226	61.4
WP_064185148.1\|2964257_2965175_-	helix-turn-helix domain-containing protein	Q8W642	Enterobacteria_phage	1.1e-38	46.9
WP_032730699.1\|2965171_2965360_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_072025957.1\|2965435_2965663_-	helix-turn-helix domain-containing protein	A0A0N7C1T6	Escherichia_phage	9.0e-16	60.0
WP_032433006.1\|2965787_2966495_+	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	4.0e-54	50.2
WP_064185149.1\|2966653_2966962_+	hypothetical protein	A0A286S1T9	Klebsiella_phage	1.6e-23	60.6
WP_064185150.1\|2966951_2967146_+	hypothetical protein	A0A286S1P8	Klebsiella_phage	7.7e-08	50.0
WP_085841219.1\|2967317_2967542_+	hypothetical protein	NA	NA	NA	NA
WP_023304721.1\|2967542_2967908_+	hypothetical protein	A0A286S1Q6	Klebsiella_phage	5.8e-57	97.5
WP_064185151.1\|2967900_2968155_+	hypothetical protein	A0A286SGR4	Klebsiella_phage	5.0e-39	94.0
WP_004177208.1\|2968126_2968345_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	6.6e-32	98.6
WP_004152156.1\|2968341_2968767_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	3.5e-53	77.9
WP_004152155.1\|2968763_2968958_+	hypothetical protein	NA	NA	NA	NA
WP_004152154.1\|2968954_2969782_+	hypothetical protein	Q8W654	Enterobacteria_phage	5.5e-111	84.0
WP_064185152.1\|2969886_2970405_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.4e-93	97.7
WP_009309074.1\|2970526_2970718_+	hypothetical protein	A0A0M4RTZ2	Salmonella_phage	2.3e-20	75.4
WP_064185153.1\|2970698_2971880_-\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	1.3e-201	84.0
WP_016197745.1\|2972076_2972625_+	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_004183778.1\|2972823_2974356_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	8.8e-22	30.0
WP_019705447.1\|2974572_2975334_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	4.1e-20	32.1
2974685:2974699	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3015806 : 3064784

Klebsiella_phage(22.22%)

protease,tail,portal,holin,integrase,head,capsid,terminase

attL 3007984:3007999|attR 3062090:3062105

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3007984:3007999	attL	NA	NA	NA	NA
WP_073901102.1\|3015806_3017099_-	hypothetical protein	B5TAB2	Burkholderia_phage	8.9e-68	36.7
WP_073900719.1\|3017971_3021049_-	kinase	A0A286S259	Klebsiella_phage	0.0e+00	61.6
WP_022615519.1\|3021045_3021426_-	nitrite transporter	A0A286S2A6	Klebsiella_phage	1.6e-57	80.2
WP_004864228.1\|3021438_3021915_-	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	4.8e-51	65.8
WP_004884312.1\|3021901_3022375_-	hypothetical protein	A0A286S298	Klebsiella_phage	1.1e-55	62.7
WP_073900721.1\|3022396_3025783_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	1.9e-303	57.7
WP_016530182.1\|3025843_3026077_-	hypothetical protein	K7PH16	Enterobacteria_phage	1.9e-08	47.2
WP_023317588.1\|3026150_3026456_-	DUF4035 domain-containing protein	Q9MCS5	Enterobacteria_phage	4.7e-28	64.6
WP_064185099.1\|3026458_3026863_-\|tail	phage tail protein	Q9MCS5	Enterobacteria_phage	5.5e-32	55.4
WP_032412035.1\|3026893_3027598_-	immunoglobulin domain-containing protein	K7PHL2	Enterobacterial_phage	9.5e-80	66.5
WP_065800435.1\|3027654_3028002_-	DUF3168 domain-containing protein	K7PKL6	Enterobacterial_phage	4.3e-33	64.6
WP_099725607.1\|3027998_3028448_-	hypothetical protein	Q9MCS9	Enterobacteria_phage	1.5e-62	81.9
WP_072071528.1\|3028444_3028783_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	1.2e-37	67.0
WP_032734570.1\|3028795_3029128_-\|head,tail	phage gp6-like head-tail connector protein	Q6JIM5	Burkholderia_virus	8.8e-12	31.6
WP_048323772.1\|3029133_3029388_-	hypothetical protein	NA	NA	NA	NA
WP_047666511.1\|3029433_3030654_-\|capsid	phage major capsid protein	Q6JIM7	Burkholderia_virus	1.7e-140	64.3
WP_064185102.1\|3030663_3031371_-\|head,protease	HK97 family phage prohead protease	Q6JIM8	Burkholderia_virus	2.4e-67	63.0
WP_064182870.1\|3031346_3032666_-\|portal	phage portal protein	Q6JIM9	Burkholderia_virus	1.7e-138	58.9
WP_025713389.1\|3032672_3034409_-\|terminase	terminase large subunit	A0A0U2C138	Paracoccus_phage	1.3e-138	45.3
WP_038808146.1\|3034362_3034827_-\|terminase	phage terminase small subunit P27 family	Q9B019	Phage_GMSE-1	4.8e-48	62.7
WP_040241924.1\|3035010_3035352_-	HNH endonuclease	K7P7P4	Enterobacteria_phage	5.4e-49	75.7
WP_071889493.1\|3035361_3035598_-	hypothetical protein	NA	NA	NA	NA
WP_004184480.1\|3036092_3036338_-	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	1.6e-34	97.5
WP_099725608.1\|3037612_3037972_-	hypothetical protein	NA	NA	NA	NA
WP_077267460.1\|3038282_3038651_-	TonB family protein	NA	NA	NA	NA
WP_073900727.1\|3039002_3039191_-	hypothetical protein	A0A286SGR9	Klebsiella_phage	5.9e-21	89.1
WP_032436040.1\|3039141_3039417_-	hypothetical protein	G8C7W1	Escherichia_phage	2.4e-23	66.3
WP_064185104.1\|3039413_3039761_-	hypothetical protein	A0A286N2Q7	Klebsiella_phage	4.4e-38	79.1
WP_004206700.1\|3039757_3040297_-	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	5.1e-102	99.4
WP_024176410.1\|3040293_3040593_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	4.5e-39	83.8
WP_012967891.1\|3041715_3042342_-	YagU family protein	NA	NA	NA	NA
WP_064185105.1\|3042594_3043410_-	molecular chaperone	A0A286N2Q2	Klebsiella_phage	8.0e-107	73.0
WP_038421389.1\|3043406_3043703_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	1.3e-35	71.9
WP_064185106.1\|3043911_3044508_-	DUF1367 family protein	K7PKS6	Enterobacteria_phage	5.5e-89	79.6
WP_023304767.1\|3044543_3044777_-	hypothetical protein	A0A0M4R5D9	Salmonella_phage	9.9e-18	57.1
WP_134726016.1\|3045451_3045931_-	hypothetical protein	NA	NA	NA	NA
WP_064185108.1\|3046269_3046818_-	hypothetical protein	NA	NA	NA	NA
WP_064185109.1\|3046852_3048835_-	DNA methyltransferase	H9C171	Pectobacterium_phage	2.1e-201	53.1
WP_060876940.1\|3048831_3049089_-	hypothetical protein	NA	NA	NA	NA
WP_064185110.1\|3049088_3049457_-	DUF977 family protein	H6WRX9	Salmonella_phage	5.4e-10	41.8
WP_064185111.1\|3049464_3050214_-	ATP-binding protein	H6WRX8	Salmonella_phage	1.2e-117	81.5
WP_064185122.1\|3050216_3051056_-	hypothetical protein	Q8HA96	Salmonella_phage	2.6e-23	52.2
WP_023279102.1\|3051121_3051916_-	ParB/RepB/Spo0J family partition protein	C7BGF1	Burkholderia_phage	1.3e-64	51.7
WP_064185112.1\|3052044_3052581_-	hypothetical protein	K7PJT7	Enterobacteria_phage	2.6e-61	70.1
WP_023279104.1\|3052592_3052814_-	hypothetical protein	A0A0M4QX15	Salmonella_phage	6.9e-21	63.0
WP_032413870.1\|3052917_3053301_+	helix-turn-helix domain-containing protein	A0A0M4R5D1	Salmonella_phage	3.4e-47	76.5
WP_023279106.1\|3053945_3054122_+	hypothetical protein	NA	NA	NA	NA
WP_064185113.1\|3054133_3055030_+	hypothetical protein	NA	NA	NA	NA
WP_157770523.1\|3055355_3055520_+	hypothetical protein	NA	NA	NA	NA
WP_064185123.1\|3055659_3055854_+	YebW family protein	NA	NA	NA	NA
WP_074194676.1\|3055862_3056018_+	DNA breaking-rejoining protein	H6WRX3	Salmonella_phage	2.6e-14	74.5
WP_099725609.1\|3056155_3059104_+	exodeoxyribonuclease	H6WRX1	Salmonella_phage	9.2e-278	53.8
WP_064185124.1\|3059116_3060226_+	recombinase RecT	H6WRX0	Salmonella_phage	4.5e-185	86.4
WP_022631172.1\|3060266_3060506_+	DUF4060 family protein	M9P0E0	Enterobacteria_phage	6.8e-22	67.5
WP_085841215.1\|3060726_3061914_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	2.4e-120	52.2
WP_004151901.1\|3062090_3062981_+	peptide ABC transporter permease SapC	NA	NA	NA	NA
3062090:3062105	attR	NA	NA	NA	NA
WP_004140266.1\|3062980_3063973_+	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	3.0e-07	27.2
WP_004140269.1\|3063974_3064784_+	peptide ABC transporter ATP-binding protein SapF	A0A2H4PQG7	Staphylococcus_phage	2.1e-14	28.9

DBSCAN-SWA_6

3467901 : 3543034

Cronobacter_phage(61.36%)

protease,tail,portal,tRNA,holin,integrase,head,capsid,terminase

attL 3511734:3511752|attR 3543106:3543124

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004224003.1\|3467901_3469623_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
WP_002898014.1\|3469667_3470369_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3470722_3470941_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002896522.1\|3471060_3473340_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_002896520.1\|3473370_3473688_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|3474013_3474235_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_032429904.1\|3474311_3476252_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.9e-38	41.4
WP_002896440.1\|3476248_3477364_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_004176693.1\|3477510_3479169_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_032429902.1\|3479587_3480283_+	aquaporin Z	NA	NA	NA	NA
WP_038806830.1\|3480398_3481298_+	lysine exporter LysO family protein	NA	NA	NA	NA
WP_004176696.1\|3481441_3483094_+	hydroxylamine reductase	NA	NA	NA	NA
WP_004147771.1\|3483104_3484073_+	NADH oxidoreductase	NA	NA	NA	NA
WP_002896408.1\|3484284_3484719_-	DoxX family protein	NA	NA	NA	NA
WP_004176700.1\|3484870_3486589_+	ubiquinone-dependent pyruvate dehydrogenase	NA	NA	NA	NA
WP_032429901.1\|3486627_3487629_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_004209682.1\|3487639_3489082_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002896399.1\|3489169_3490183_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004209681.1\|3490179_3491010_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	4.1e-05	31.6
WP_004176708.1\|3491041_3492181_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_002896394.1\|3493059_3493575_+	lipoprotein	NA	NA	NA	NA
WP_002896392.1\|3493801_3494530_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	1.2e-29	37.1
WP_002896390.1\|3494550_3495282_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896386.1\|3495288_3496005_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_004141917.1\|3496004_3496673_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_002896384.1\|3496856_3497588_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896382.1\|3497674_3499147_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	7.9e-28	31.8
WP_002896380.1\|3499143_3499860_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.1e-34	36.9
WP_004147758.1\|3499938_3501066_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A2K5B251	Erysipelothrix_phage	1.8e-19	25.6
WP_002896376.1\|3501107_3501596_-	DUF2593 family protein	NA	NA	NA	NA
WP_002896372.1\|3501653_3502499_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_002896371.1\|3502495_3503449_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_002896370.1\|3503459_3504593_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	2.2e-30	34.9
WP_002896368.1\|3504756_3505869_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_002896365.1\|3506217_3506697_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_002896363.1\|3506785_3507688_-	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	2.0e-34	35.3
WP_004179133.1\|3507802_3508525_-	nitroreductase NfsA	NA	NA	NA	NA
WP_004179132.1\|3508508_3508796_-	YbjC family protein	NA	NA	NA	NA
WP_002896352.1\|3508998_3509262_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	1.6e-27	73.1
WP_002896351.1\|3509268_3509652_-	membrane protein	NA	NA	NA	NA
WP_004147745.1\|3509918_3511604_+	aspartate:alanine antiporter	NA	NA	NA	NA
3511734:3511752	attL	NA	NA	NA	NA
WP_099725619.1\|3512068_3512254_+	hypothetical protein	NA	NA	NA	NA
WP_142367404.1\|3512296_3513094_+	hypothetical protein	NA	NA	NA	NA
WP_099725620.1\|3513605_3515285_-	hypothetical protein	F1BUJ7	Cronobacter_phage	2.7e-189	59.0
WP_064185068.1\|3515288_3515840_-	hypothetical protein	F1BUJ9	Cronobacter_phage	4.8e-55	67.2
WP_064185067.1\|3515811_3516537_-	hypothetical protein	F1BUK1	Cronobacter_phage	3.6e-50	47.1
WP_064185066.1\|3516536_3516776_-	hypothetical protein	NA	NA	NA	NA
WP_064185065.1\|3516798_3519411_-	hypothetical protein	F1BUK3	Cronobacter_phage	1.1e-93	59.8
WP_064185064.1\|3519420_3520059_-	hypothetical protein	F1BUK5	Cronobacter_phage	2.5e-71	70.4
WP_064185063.1\|3520051_3521236_-	hypothetical protein	F1BUK6	Cronobacter_phage	5.5e-173	76.2
WP_064185062.1\|3521232_3521562_-	DUF2590 family protein	F1BUK8	Cronobacter_phage	2.1e-37	70.6
WP_064185061.1\|3521558_3523442_-\|tail	phage tail tape measure protein	F1BUK9	Cronobacter_phage	1.5e-225	61.1
WP_157770524.1\|3523441_3523597_-	hypothetical protein	NA	NA	NA	NA
WP_064185060.1\|3523629_3523893_-	hypothetical protein	A5X9I7	Aeromonas_virus	3.5e-19	56.1
WP_064185059.1\|3524039_3524372_-	hypothetical protein	F1BUL2	Cronobacter_phage	1.1e-35	70.0
WP_064185058.1\|3524371_3524713_-	M15 family metallopeptidase	F1BUL3	Cronobacter_phage	9.0e-52	94.1
WP_042920132.1\|3524709_3525000_-\|holin	holin	C7BGD7	Burkholderia_phage	8.8e-16	50.6
WP_064185056.1\|3525009_3525468_-	DUF2597 family protein	F1BUL4	Cronobacter_phage	1.1e-57	74.0
WP_064185055.1\|3525464_3526583_-	DUF2586 domain-containing protein	F1BUL5	Cronobacter_phage	5.2e-149	71.7
WP_064185054.1\|3526569_3527286_-	hypothetical protein	F1BUL6	Cronobacter_phage	6.4e-92	72.6
WP_064185053.1\|3527285_3527789_-\|tail	phage tail protein	F1BUL7	Cronobacter_phage	6.3e-62	67.1
WP_042920119.1\|3527785_3528238_-\|head	head completion/stabilization protein	F1BUL8	Cronobacter_phage	1.8e-60	78.0
WP_099725621.1\|3528334_3529036_-\|terminase	terminase	F1BUM0	Cronobacter_phage	1.1e-83	63.8
WP_064185051.1\|3529039_3530062_-\|capsid	phage major capsid protein, P2 family	F1BUM2	Cronobacter_phage	1.5e-158	81.8
WP_064185050.1\|3530124_3530919_-\|capsid	phage capsid protein	F1BUM4	Cronobacter_phage	4.8e-64	53.0
WP_099725622.1\|3531091_3532864_+\|terminase	terminase	F1BUM5	Cronobacter_phage	7.5e-291	82.4
WP_099725623.1\|3532860_3533910_+\|portal	phage portal protein	F1BUM7	Cronobacter_phage	6.4e-157	78.0
WP_038431884.1\|3533906_3534230_+	ogr/Delta-like zinc finger family protein	F1BUM8	Cronobacter_phage	4.4e-48	90.4
WP_099725625.1\|3534535_3536557_-	replication endonuclease	F1BUM9	Cronobacter_phage	5.3e-301	74.2
WP_099725626.1\|3536553_3537405_-	DNA adenine methylase	F1BUN1	Cronobacter_phage	2.5e-143	92.7
WP_099725627.1\|3537395_3537629_-	DUF2732 family protein	NA	NA	NA	NA
WP_099725628.1\|3537695_3538097_-	hypothetical protein	F1BUN2	Cronobacter_phage	1.7e-38	53.4
WP_038431890.1\|3538096_3538525_-	hypothetical protein	F1BUN5	Cronobacter_phage	2.2e-23	48.4
WP_038431891.1\|3538718_3539222_-	hypothetical protein	F1BUN6	Cronobacter_phage	5.6e-58	70.7
WP_099725629.1\|3539254_3539476_-	regulator	NA	NA	NA	NA
WP_038431893.1\|3539601_3540168_+	phage repressor protein CI	F1BUN8	Cronobacter_phage	1.0e-36	42.2
WP_038431894.1\|3540170_3541304_+	AAA family ATPase	NA	NA	NA	NA
WP_038431895.1\|3541309_3541906_+	DUF4276 family protein	NA	NA	NA	NA
WP_038431896.1\|3541978_3543034_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	5.2e-106	57.6
3543106:3543124	attR	NA	NA	NA	NA

DBSCAN-SWA_7

4635784 : 4711851

Escherichia_phage(18.18%)

holin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019725322.1\|4635784_4639171_+\|holin	choline trimethylamine-lyase	A0A1S6UAD4	Serratia_phage	9.7e-05	45.0
WP_004182804.1\|4639256_4640204_+\|holin	choline TMA-lyase-activating enzyme	NA	NA	NA	NA
WP_004182802.1\|4640216_4640615_+	BMC domain-containing protein	NA	NA	NA	NA
WP_021441127.1\|4640611_4641232_+	phosphate propanoyltransferase	NA	NA	NA	NA
WP_021441126.1\|4641244_4641913_+	hypothetical protein	NA	NA	NA	NA
WP_020316589.1\|4641944_4642358_+	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_004204123.1\|4642375_4642705_+	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_021441125.1\|4642905_4643913_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_004178470.1\|4644219_4645287_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_021441124.1\|4645283_4648028_+	ribosome-associated ATPase/putative transporter RbbA	A0A2H4PQG7	Staphylococcus_phage	2.7e-21	30.7
WP_032428511.1\|4648027_4649152_+	ABC-2 transporter permease	NA	NA	NA	NA
WP_021441122.1\|4649192_4649510_-	hypothetical protein	NA	NA	NA	NA
WP_021441121.1\|4655702_4656824_+	cupin domain-containing protein	NA	NA	NA	NA
WP_004178461.1\|4656871_4657405_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002887278.1\|4657415_4657682_-	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_021441120.1\|4657784_4659218_-	Cu(+)/Ag(+) sensor histidine kinase	A0A1V0SGX0	Hokovirus	2.0e-12	27.6
WP_002887273.1\|4659207_4659891_-	copper response regulator transcription factor CusR	W8CYM9	Bacillus_phage	7.9e-31	36.0
WP_038806759.1\|4660063_4661449_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_021441118.1\|4661466_4661811_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_021441117.1\|4661855_4663118_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_026055975.1\|4665869_4666793_-\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	8.4e-177	99.7
WP_021441109.1\|4667043_4668363_-	xylose isomerase	NA	NA	NA	NA
WP_004178429.1\|4668774_4670229_+	MFS transporter	NA	NA	NA	NA
WP_099725648.1\|4670287_4671967_+	glycoside hydrolase family 43 protein	NA	NA	NA	NA
WP_021441107.1\|4672049_4672688_-	HNH endonuclease	NA	NA	NA	NA
WP_000183578.1\|4673738_4674548_-	hypothetical protein	NA	NA	NA	NA
WP_021441105.1\|4674645_4676868_+	glycosyltransferase	NA	NA	NA	NA
WP_021441102.1\|4678772_4679900_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_004192273.1\|4679889_4680153_+	hypothetical protein	NA	NA	NA	NA
WP_099725649.1\|4680314_4681556_+	conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_004178415.1\|4681518_4681785_+	hypothetical protein	NA	NA	NA	NA
WP_021441098.1\|4682727_4684215_+	hypothetical protein	NA	NA	NA	NA
WP_104467992.1\|4684497_4685609_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.9e-05	24.4
WP_044865629.1\|4686541_4687057_+	hypothetical protein	NA	NA	NA	NA
WP_012695466.1\|4688215_4689139_+\|transposase	IS5-like element IS903B family transposase	Q1MVF0	Enterobacteria_phage	4.6e-175	98.7
WP_072031781.1\|4689567_4689909_-	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
WP_017694582.1\|4689919_4690462_-	DNA repair protein RadC	NA	NA	NA	NA
WP_017694583.1\|4690474_4690918_-	antirestriction protein	A9J566	Pseudomonas_phage	3.9e-15	30.1
WP_023343037.1\|4690948_4691770_-	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	5.7e-44	36.5
WP_023343036.1\|4691889_4692363_-	hypothetical protein	NA	NA	NA	NA
WP_026094405.1\|4692434_4692887_-	hypothetical protein	NA	NA	NA	NA
WP_012543038.1\|4692922_4693639_-	WYL domain-containing protein	NA	NA	NA	NA
WP_099725650.1\|4693882_4694758_-	GTPase family protein	NA	NA	NA	NA
WP_047670580.1\|4695037_4697203_-	hypothetical protein	NA	NA	NA	NA
WP_017694594.1\|4697581_4698499_-	hypothetical protein	NA	NA	NA	NA
WP_017694595.1\|4698913_4699492_+	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_017694596.1\|4699598_4699805_+	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_017694597.1\|4699900_4700524_+	hypothetical protein	NA	NA	NA	NA
WP_017694598.1\|4700733_4700961_-	hypothetical protein	NA	NA	NA	NA
WP_017694600.1\|4701560_4704215_-	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_017694601.1\|4704204_4706106_-	hypothetical protein	NA	NA	NA	NA
WP_047670511.1\|4706102_4707485_-	hypothetical protein	NA	NA	NA	NA
WP_023343028.1\|4707665_4709789_-	ATP-dependent helicase	G3MA40	Bacillus_virus	2.4e-09	24.8
WP_026055975.1\|4710927_4711851_-\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	8.4e-177	99.7

DBSCAN-SWA_8

5048966 : 5071518

Escherichia_phage(40.0%)

integrase,transposase

attL 5048910:5048928|attR 5080416:5080434

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5048910:5048928	attL	NA	NA	NA	NA
WP_001067855.1\|5048966_5049671_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_032140899.1\|5051292_5051535_+	hypothetical protein	NA	NA	NA	NA
WP_000470728.1\|5051566_5052244_-	tetracycline resistance transcriptional repressor TetR(A)	NA	NA	NA	NA
WP_000804064.1\|5052322_5053522_+	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_000058717.1\|5053553_5054438_-	EamA family transporter	NA	NA	NA	NA
WP_001351729.1\|5054575_5054968_-	cysteine hydrolase	NA	NA	NA	NA
WP_000509965.1\|5055744_5056350_-	recombinase family protein	A0A1W5LU24	Ralstonia_phage	1.9e-12	31.2
WP_001553819.1\|5056444_5059342_+\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	4.2e-182	37.8
WP_014386481.1\|5061749_5062394_+	quinolone resistance pentapeptide repeat protein QnrB1	NA	NA	NA	NA
WP_001067855.1\|5063266_5063971_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000845048.1\|5064516_5065530_-\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_004201280.1\|5065685_5066159_+	trimethoprim-resistant dihydrofolate reductase DfrA14	A0A140HLG8	Bacillus_phage	5.3e-18	33.8
WP_001144737.1\|5066379_5066646_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_001389365.1\|5066788_5067553_+\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_004098817.1\|5067813_5069028_+	type II site-specific deoxyribonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
WP_001288432.1\|5069061_5070495_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	7.0e-106	50.6
WP_001067855.1\|5070813_5071518_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
5080416:5080434	attR	NA	NA	NA	NA

DBSCAN-SWA_9

5146955 : 5209709

Bacillus_phage(26.67%)

protease,integrase,transposase

attL 5135759:5135774|attR 5181126:5181141

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5135759:5135774	attL	NA	NA	NA	NA
WP_001515717.1\|5146955_5147696_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
WP_032430723.1\|5148839_5149787_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_071527918.1\|5149813_5150125_-	EAL domain-containing protein	NA	NA	NA	NA
WP_004182026.1\|5150189_5151113_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	7.1e-176	98.7
WP_004197688.1\|5151785_5152043_-	hypothetical protein	NA	NA	NA	NA
WP_080895248.1\|5152662_5154099_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004152070.1\|5155081_5156359_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_004178088.1\|5156421_5158419_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	9.7e-21	25.9
WP_085955172.1\|5159458_5160666_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.7e-100	63.2
WP_004178091.1\|5162094_5162526_-	silver-binding protein SilE	NA	NA	NA	NA
WP_003032875.1\|5162776_5164252_-	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_001572351.1\|5164244_5164925_-	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.1e-31	35.6
WP_000475512.1\|5165114_5166500_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_001246153.1\|5166528_5166882_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_004098959.1\|5166995_5168288_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_004098958.1\|5168298_5171445_+	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	NA	NA	NA	NA
WP_000758228.1\|5171531_5171972_+	hypothetical protein	NA	NA	NA	NA
WP_023317528.1\|5172098_5174552_+	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	9.9e-84	35.5
WP_000843497.1\|5174592_5174790_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_004182013.1\|5174823_5175561_-	peptidoglycan DD-metalloendopeptidase family protein	A8ATH6	Listeria_phage	3.6e-13	41.0
WP_001023257.1\|5175849_5176299_-	copper resistance protein	NA	NA	NA	NA
WP_000925242.1\|5176532_5178350_+	multicopper oxidase PcoA	NA	NA	NA	NA
WP_001242438.1\|5178349_5179246_+	copper resistance outer membrane transporter PcoB	NA	NA	NA	NA
WP_000025662.1\|5179285_5179666_+	copper resistance system metallochaperone PcoC	NA	NA	NA	NA
WP_004118344.1\|5179670_5180600_+	copper resistance inner membrane protein PcoD	NA	NA	NA	NA
WP_001188930.1\|5180654_5181335_+	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4
5181126:5181141	attR	NA	NA	NA	NA
WP_004152084.1\|5181331_5182732_+	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	4.1e-18	26.3
WP_004152085.1\|5182948_5183383_+	copper resistance system metallochaperone PcoE	NA	NA	NA	NA
WP_024623170.1\|5183614_5183794_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_004196769.1\|5185536_5186046_+	major intrinsic family protein	NA	NA	NA	NA
WP_004196778.1\|5186095_5186593_-	N-acetyltransferase	NA	NA	NA	NA
WP_004152092.1\|5186924_5187251_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085921126.1\|5187250_5187961_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	2.9e-92	77.0
WP_004182005.1\|5187969_5188515_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004152095.1\|5188590_5188953_+	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
WP_004152096.1\|5190849_5191386_+	N-acetyltransferase	NA	NA	NA	NA
WP_004152097.1\|5191418_5191844_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.3e-52	72.9
WP_004152098.1\|5191856_5193146_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4J144	uncultured_Caudovirales_phage	1.9e-171	74.0
WP_004152099.1\|5193193_5194945_-	arsenite efflux transporter ATPase subunit ArsA	NA	NA	NA	NA
WP_004152100.1\|5194962_5195325_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_004152101.1\|5195374_5195725_-	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	1.4e-23	50.9
WP_019725036.1\|5196082_5196331_+	hypothetical protein	NA	NA	NA	NA
WP_015065504.1\|5196327_5196900_+	hypothetical protein	NA	NA	NA	NA
WP_009310053.1\|5196930_5197425_+	hypothetical protein	NA	NA	NA	NA
WP_015065502.1\|5197468_5197837_+	hypothetical protein	NA	NA	NA	NA
WP_019725040.1\|5197870_5198074_+	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_019725034.1\|5198087_5198318_+	hypothetical protein	NA	NA	NA	NA
WP_019725033.1\|5198361_5198556_-	hypothetical protein	NA	NA	NA	NA
WP_003026799.1\|5198762_5199029_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_003026803.1\|5199016_5199499_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_077253535.1\|5199706_5201053_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_004143398.1\|5201101_5201497_+	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_004152113.1\|5202986_5203949_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_009483782.1\|5203935_5204685_-	diguanylate cyclase	NA	NA	NA	NA
WP_004152115.1\|5204922_5205120_-	hypothetical protein	NA	NA	NA	NA
WP_004152116.1\|5205119_5207915_-	heat shock survival AAA family ATPase ClpK	K4FB40	Cronobacter_phage	5.2e-129	41.0
WP_004152117.1\|5208038_5208608_-	small heat shock protein sHSP20	NA	NA	NA	NA
WP_004152118.1\|5208642_5208924_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004118208.1\|5209167_5209431_-	hypothetical protein	NA	NA	NA	NA
WP_004118209.1\|5209445_5209709_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_10

5222211 : 5293297

Escherichia_phage(26.32%)

integrase,transposase

attL 5223383:5223442|attR 5277341:5278681

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072143344.1\|5222211_5223180_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	2.0e-173	91.6
5223383:5223442	attL	NA	NA	NA	NA
WP_000427619.1\|5223453_5224458_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_004118832.1\|5226417_5228151_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-15	28.7
WP_004118225.1\|5228158_5229106_-	acetamidase/formamidase family protein	NA	NA	NA	NA
WP_004152278.1\|5229150_5230755_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004118227.1\|5230767_5231688_-	ABC transporter permease	NA	NA	NA	NA
WP_004118228.1\|5231687_5232536_-	ABC transporter permease	NA	NA	NA	NA
WP_004118229.1\|5232532_5233126_-	ANTAR domain-containing protein	NA	NA	NA	NA
WP_004118840.1\|5233122_5234250_-	transporter substrate-binding protein	NA	NA	NA	NA
WP_004118231.1\|5234534_5234702_-\|integrase	integrase	NA	NA	NA	NA
WP_004197062.1\|5235804_5236326_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004197067.1\|5236322_5237276_+	fec operon regulator FecR	NA	NA	NA	NA
WP_032430169.1\|5237368_5239693_+	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_023157913.1\|5239737_5240640_+	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_004118243.1\|5240636_5241635_+	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_004118246.1\|5241631_5242588_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	5.3e-17	26.1
WP_004152282.1\|5242588_5243356_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	9.8e-14	25.2
WP_004118251.1\|5243454_5243748_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.7e-49	96.9
WP_071785586.1\|5244078_5244321_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000427619.1\|5244618_5245623_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_004152286.1\|5246209_5247292_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	6.8e-186	96.4
WP_029498501.1\|5247413_5250488_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	96.6
WP_023158026.1\|5250539_5251793_+	lactose permease	NA	NA	NA	NA
WP_058350821.1\|5252762_5253017_-	hypothetical protein	NA	NA	NA	NA
WP_004197675.1\|5254041_5255685_-	alpha-D-glucose phosphate-specific phosphoglucomutase	NA	NA	NA	NA
WP_023157975.1\|5255798_5258246_-	glycogen phosphorylase	A0A140XAG6	Dickeya_phage	6.1e-25	69.2
WP_009653212.1\|5258264_5259698_-	glycogen synthase GlgA	NA	NA	NA	NA
WP_004099051.1\|5259786_5261070_-	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_004099052.1\|5261199_5263392_-	1,4-alpha-glucan branching enzyme	NA	NA	NA	NA
WP_040147694.1\|5263809_5264712_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	1.5e-167	99.0
WP_019706030.1\|5266424_5267429_+	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|5270407_5271112_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_011977766.1\|5272132_5272468_-	C2H2-type zinc finger protein	NA	NA	NA	NA
WP_001568067.1\|5272640_5272922_+	hypothetical protein	NA	NA	NA	NA
WP_000176305.1\|5272975_5273587_+	DUF2913 family protein	NA	NA	NA	NA
WP_001445937.1\|5273771_5274728_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|5275108_5275813_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000427619.1\|5277411_5278416_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_000954592.1\|5278597_5278774_-	DUF4102 domain-containing protein	T1S9J3	Salmonella_phage	1.0e-06	68.6
5277341:5278681	attR	NA	NA	NA	NA
WP_001043260.1\|5279103_5279919_+	sulfonamide-resistant dihydropteroate synthase Sul2	NA	NA	NA	NA
WP_001082319.1\|5279979_5280783_+	aminoglycoside O-phosphotransferase APH(3'')-Ib	Q75ZG1	Hepacivirus	4.9e-24	34.3
WP_000480968.1\|5280782_5281619_+	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001120891.1\|5281590_5282130_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000027057.1\|5282339_5283200_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|5283382_5283940_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000608644.1\|5284503_5285766_+\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_000239590.1\|5286021_5286897_+	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
WP_001393253.1\|5286943_5287276_-	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
WP_001067855.1\|5289597_5290302_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001334766.1\|5290933_5291764_-	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_063840321.1\|5291894_5292449_-	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
WP_001067855.1\|5292592_5293297_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP024490

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP024489

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection