CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NZ_CP024535	Klebsiella pneumoniae strain KSB1_9D chromosome, complete genome	1 crisprs	csa3,cas3,DEDDh,DinG,RT,WYL	6
NZ_CP024539	Klebsiella pneumoniae strain KSB1_9D plasmid unnamed4, complete sequence	0 crisprs	NA	0
NZ_CP024536	Klebsiella pneumoniae strain KSB1_9D plasmid unnamed1, complete sequence	0 crisprs	DEDDh	2
NZ_CP024537	Klebsiella pneumoniae strain KSB1_9D plasmid unnamed2, complete sequence	0 crisprs	csa3,RT	1
NZ_CP024541	Klebsiella pneumoniae strain KSB1_9D plasmid unnamed6, complete sequence	0 crisprs	NA	0
NZ_CP024540	Klebsiella pneumoniae strain KSB1_9D plasmid unnamed5, complete sequence	0 crisprs	NA	0
NZ_CP024538	Klebsiella pneumoniae strain KSB1_9D plasmid unnamed3, complete sequence	0 crisprs	RT	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1727 : 64517

uncultured_Caudovirales_phage(27.78%)

transposase,integrase,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001515717.1\|1727_2468_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
WP_004152065.1\|3611_4559_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	1.8e-12	30.6
WP_071527918.1\|4585_4897_-	EAL domain-containing protein	NA	NA	NA	NA
WP_004152067.1\|4961_5885_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	2.1e-175	98.4
WP_004197688.1\|6557_6815_-	hypothetical protein	NA	NA	NA	NA
WP_020444838.1\|7416_8871_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004152070.1\|9853_11131_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_004178088.1\|11193_13191_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	9.7e-21	25.9
WP_085955172.1\|14230_15438_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.7e-100	63.2
WP_004178091.1\|16866_17298_-	silver-binding protein SilE	NA	NA	NA	NA
WP_003032875.1\|17548_19024_-	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_001572351.1\|19016_19697_-	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.1e-31	35.6
WP_000475512.1\|19886_21272_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_001246153.1\|21300_21654_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_004152079.1\|21767_23060_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_004098958.1\|23070_26217_+	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	S5VTK5	Leptospira_phage	4.0e-61	22.5
WP_000758228.1\|26303_26744_+	hypothetical protein	NA	NA	NA	NA
WP_004098955.1\|26870_29318_+	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	7.6e-84	35.8
WP_000843497.1\|29358_29556_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_004118669.1\|29589_30327_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4JAF5	uncultured_Caudovirales_phage	1.2e-11	32.5
WP_001023257.1\|30615_31065_-	copper resistance protein	NA	NA	NA	NA
WP_000925242.1\|31298_33116_+	multicopper oxidase PcoA	NA	NA	NA	NA
WP_001242438.1\|33115_34012_+	copper resistance outer membrane transporter PcoB	NA	NA	NA	NA
WP_000025662.1\|34051_34432_+	copper resistance system metallochaperone PcoC	NA	NA	NA	NA
WP_004118344.1\|34436_35366_+	copper resistance inner membrane protein PcoD	NA	NA	NA	NA
WP_001188930.1\|35420_36101_+	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4
WP_004152084.1\|36097_37498_+	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	4.1e-18	26.3
WP_004152085.1\|37714_38149_+	copper resistance system metallochaperone PcoE	NA	NA	NA	NA
WP_004152086.1\|38380_38560_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_031944101.1\|40302_40812_+	major intrinsic protein MIP	NA	NA	NA	NA
WP_004152091.1\|40861_41359_-	N-acetyltransferase	NA	NA	NA	NA
WP_004152092.1\|41690_42017_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085903505.1\|42016_42727_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	2.9e-92	77.0
WP_004182005.1\|42735_43281_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004152095.1\|43356_43719_+	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
WP_004152096.1\|45615_46152_+	N-acetyltransferase	NA	NA	NA	NA
WP_004152097.1\|46184_46610_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.3e-52	72.9
WP_004152098.1\|46622_47912_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4J144	uncultured_Caudovirales_phage	1.9e-171	74.0
WP_004152099.1\|47959_49711_-	arsenite efflux transporter ATPase subunit ArsA	NA	NA	NA	NA
WP_004152100.1\|49728_50091_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_004152101.1\|50140_50491_-	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	1.4e-23	50.9
WP_004152102.1\|50848_51118_+	hypothetical protein	NA	NA	NA	NA
WP_004152103.1\|51105_51681_+	hypothetical protein	NA	NA	NA	NA
WP_004152104.1\|51711_52206_+	DNA-binding protein	NA	NA	NA	NA
WP_004152105.1\|52249_52618_+	hypothetical protein	NA	NA	NA	NA
WP_004152106.1\|52651_52855_+	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_004152107.1\|52903_53161_+	hypothetical protein	NA	NA	NA	NA
WP_004152108.1\|53236_53491_+	hypothetical protein	NA	NA	NA	NA
WP_003026799.1\|53666_53933_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_003026803.1\|53920_54403_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020314316.1\|54614_55961_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_004152113.1\|57803_58766_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_009483782.1\|58752_59502_-	diguanylate cyclase	NA	NA	NA	NA
WP_004152115.1\|59739_59937_-	hypothetical protein	NA	NA	NA	NA
WP_004152116.1\|59936_62732_-	heat shock survival AAA family ATPase ClpK	K4FB40	Cronobacter_phage	5.2e-129	41.0
WP_004152117.1\|62846_63416_-	small heat shock protein sHSP20	NA	NA	NA	NA
WP_004152118.1\|63450_63732_-	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	5.2e-05	38.2
WP_004118208.1\|63975_64239_-	hypothetical protein	NA	NA	NA	NA
WP_004118209.1\|64253_64517_+\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP024535

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP024535_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP024535_1

4417187-4417281

Orphan

Consensus_repeat	Method
ACTATGGTTTTTATGGTTTTTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP024535_1

>merge|NZ_CP024535|1|4417187-4417281|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATGGTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATGACTGTGGTTTTTATGGTTTTTATT

>NZ_CP024535|1|1|4417187-4417281|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATG	GTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATG
ACTGTGGTTTTTATGGTTTTTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024535.1\|WP_002888324.1\|4425520_4426342_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP024535.1\|WP_002888353.1\|4407945_4408641_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP024535.1\|WP_002888323.1\|4426344_4426722_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP024535.1\|WP_002888329.1\|4423242_4424529_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP024535.1\|WP_002888320.1\|4427830_4428310_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP024535.1\|WP_002888370.1\|4403402_4404248_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP024535.1\|WP_002888337.1\|4419037_4419736_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP024535.1\|WP_002888340.1\|4417422_4419048_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP024535.1\|WP_002888373.1\|4402506_4403274_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP024535.1\|WP_002888347.1\|4415014_4415554_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP024535.1\|WP_002888332.1\|4419768_4420596_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP024535.1\|WP_002888368.1\|4404585_4406295_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP024535.1\|WP_002888321.1\|4426726_4427575_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP024535.1\|WP_004151368.1\|4411361_4414268_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP024535.1\|WP_002888357.1\|4406305_4407808_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP024535.1\|WP_002888345.1\|4415733_4417098_-\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP024535.1\|WP_002888348.1\|4414280_4414940_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP024535.1\|WP_002888349.1\|4408816_4411174_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP024535.1\|WP_004147026.1\|4420839_4423188_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP024535.1\|WP_002888327.1\|4424534_4425524_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696

Protein	Function_ID	Function_description	E-value
NZ_CP024535.1\|WP_002888324.1\|4425520_4426342_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
NZ_CP024535.1\|WP_002888353.1\|4407945_4408641_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP024535.1\|WP_002888323.1\|4426344_4426722_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
NZ_CP024535.1\|WP_002888329.1\|4423242_4424529_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP024535.1\|WP_002888320.1\|4427830_4428310_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
NZ_CP024535.1\|WP_002888370.1\|4403402_4404248_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP024535.1\|WP_002888337.1\|4419037_4419736_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	5.03078e-66
NZ_CP024535.1\|WP_002888340.1\|4417422_4419048_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	6.55037e-173
NZ_CP024535.1\|WP_002888373.1\|4402506_4403274_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP024535.1\|WP_002888347.1\|4415014_4415554_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
NZ_CP024535.1\|WP_002888332.1\|4419768_4420596_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
NZ_CP024535.1\|WP_002888368.1\|4404585_4406295_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP024535.1\|WP_002888321.1\|4426726_4427575_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP024535.1\|WP_004151368.1\|4411361_4414268_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP024535.1\|WP_002888357.1\|4406305_4407808_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP024535.1\|WP_002888345.1\|4415733_4417098_-\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
NZ_CP024535.1\|WP_002888348.1\|4414280_4414940_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
NZ_CP024535.1\|WP_002888349.1\|4408816_4411174_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP024535.1\|WP_004147026.1\|4420839_4423188_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP024535.1\|WP_002888327.1\|4424534_4425524_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0

>NZ_CP024535.1|WP_002888345.1|4415733_4417098_-|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP024535.1|WP_002888347.1|4415014_4415554_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>NZ_CP024535.1|WP_002888348.1|4414280_4414940_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP024535.1|WP_004151368.1|4411361_4414268_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESIDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAGIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP024535.1|WP_002888349.1|4408816_4411174_+|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLIEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSHVNAWWAQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP024535.1|WP_002888353.1|4407945_4408641_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP024535.1|WP_002888357.1|4406305_4407808_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATVEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP024535.1|WP_002888368.1|4404585_4406295_+|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSKAALTH
>NZ_CP024535.1|WP_002888370.1|4403402_4404248_-|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVREACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP024535.1|WP_002888373.1|4402506_4403274_-|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR
>NZ_CP024535.1|WP_002888340.1|4417422_4419048_+|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEAHDAS
>NZ_CP024535.1|WP_002888337.1|4419037_4419736_+|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSDREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP024535.1|WP_002888332.1|4419768_4420596_-|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP024535.1|WP_004147026.1|4420839_4423188_+|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP024535.1|WP_002888329.1|4423242_4424529_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP024535.1|WP_002888327.1|4424534_4425524_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP024535.1|WP_002888324.1|4425520_4426342_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP024535.1|WP_002888323.1|4426344_4426722_+|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP024535.1|WP_002888321.1|4426726_4427575_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP024535.1|WP_002888320.1|4427830_4428310_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

453139 : 525274

uncultured_Caudovirales_phage(55.0%)

tail,tRNA,transposase,terminase,protease,capsid,head,portal,integrase

attL 470892:470909|attR 488193:488210

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002919147.1\|453139_454087_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	2.2e-07	37.2
WP_002919144.1\|454101_454611_-	peptide deformylase	E3SLL2	Synechococcus_phage	2.6e-18	40.3
WP_002919139.1\|454739_455864_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_002919137.1\|455835_456309_+	DUF494 domain-containing protein	NA	NA	NA	NA
WP_004145330.1\|456334_456877_+	hypothetical protein	NA	NA	NA	NA
WP_002919132.1\|456881_457454_+	L-threonylcarbamoyladenylate synthase type 1 TsaC	NA	NA	NA	NA
WP_002919126.1\|457457_458276_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_002919125.1\|458272_458530_+	DUF1488 domain-containing protein	NA	NA	NA	NA
WP_002919123.1\|458505_459060_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_002919103.1\|465000_465222_-	membrane protein	NA	NA	NA	NA
WP_002919102.1\|465515_468626_-	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_002919101.1\|468638_469778_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004150972.1\|470156_470807_+	acrEF/envCD operon transcriptional regulator	NA	NA	NA	NA
470892:470909	attL	NA	NA	NA	NA
WP_004150971.1\|471082_472309_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.8e-150	62.2
WP_004150970.1\|472401_473343_+	hypothetical protein	NA	NA	NA	NA
WP_099595205.1\|473524_473782_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_085955245.1\|473784_474977_-\|transposase	IS3-like element ISKpn18 family transposase	U5P429	Shigella_phage	3.5e-50	43.5
WP_004150969.1\|475125_475905_+	hypothetical protein	Q8HA02	Enterobacteria_phage	6.2e-40	51.5
WP_106918304.1\|476356_476626_+	host cell division inhibitor Icd-like protein	A0A2H4JGW3	uncultured_Caudovirales_phage	2.4e-44	94.4
WP_001549752.1\|476618_476807_+	hypothetical protein	NA	NA	NA	NA
WP_004150967.1\|476799_477114_+	hypothetical protein	NA	NA	NA	NA
WP_004150966.1\|477110_477479_+	hypothetical protein	A0A2H4JCX7	uncultured_Caudovirales_phage	3.7e-51	81.1
WP_001549749.1\|477475_477841_+	hypothetical protein	NA	NA	NA	NA
WP_004150965.1\|477840_479976_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	3.4e-205	62.4
WP_004150964.1\|480318_480654_+	hypothetical protein	NA	NA	NA	NA
WP_004150963.1\|480702_481215_-	hypothetical protein	NA	NA	NA	NA
WP_001549743.1\|481478_482645_+\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	9.8e-207	95.9
WP_001547826.1\|482696_483257_+\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.2e-98	95.7
WP_004150962.1\|483258_484500_+\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	1.0e-230	96.5
WP_004150961.1\|484496_484832_+\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	3.7e-26	57.8
WP_001547824.1\|484828_485128_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	3.4e-39	80.8
WP_004150959.1\|485127_485571_+	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	2.8e-77	91.8
WP_000113647.1\|485846_486203_+\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	5.5e-60	99.2
WP_004150955.1\|486186_487848_+\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	0.0e+00	98.0
WP_004150954.1\|487850_488042_+	hypothetical protein	NA	NA	NA	NA
WP_000462905.1\|488195_488492_-	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
488193:488210	attR	NA	NA	NA	NA
WP_004144972.1\|488516_489482_-\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_002918745.1\|489839_490721_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_002918742.1\|490732_492184_-	sodium/pantothenate symporter	NA	NA	NA	NA
WP_002918740.1\|492173_492416_-	YhdT family protein	NA	NA	NA	NA
WP_002918738.1\|492526_493876_-	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_002918736.1\|493886_494354_-	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_002918732.1\|494376_494829_-	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_002918689.1\|495052_495661_-	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_002918688.1\|495660_496662_-	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_002918687.1\|496890_497082_+	hypothetical protein	NA	NA	NA	NA
WP_085955245.1\|497416_498608_+\|transposase	IS3-like element ISKpn18 family transposase	U5P429	Shigella_phage	3.5e-50	43.5
WP_002918653.1\|500713_501757_+	rod shape-determining protein	F2Y0P3	Organic_Lake_phycodnavirus	6.7e-05	22.3
WP_004149974.1\|501827_502820_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_002918648.1\|502819_503308_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_002918646.1\|503315_503897_+	septum formation inhibitor Maf	NA	NA	NA	NA
WP_002918644.1\|503899_505369_+	ribonuclease G	NA	NA	NA	NA
WP_004150952.1\|505406_509204_+	AsmA2 domain-containing protein	NA	NA	NA	NA
WP_002918642.1\|509292_510738_+\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_002918641.1\|510773_511703_-	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
WP_002918640.1\|511834_512038_+	AaeX family protein	NA	NA	NA	NA
WP_002918639.1\|512045_512978_+	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_002918632.1\|512983_514951_+	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_002918629.1\|515030_515306_+	hypothetical protein	NA	NA	NA	NA
WP_002918627.1\|515356_515623_-	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_002918626.1\|515721_515985_-	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_002918625.1\|516360_516831_-	transcriptional regulator ArgR	NA	NA	NA	NA
WP_002918570.1\|517245_518184_+	malate dehydrogenase	NA	NA	NA	NA
WP_002918568.1\|518320_519379_-	outer membrane-stress sensor serine endopeptidase DegS	NA	NA	NA	NA
WP_002918566.1\|519466_520834_-\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	6.0e-22	25.3
WP_002918565.1\|521007_521406_-	DUF1043 family protein	NA	NA	NA	NA
WP_004144945.1\|521596_522724_+	cell division protein ZapE	NA	NA	NA	NA
WP_002918559.1\|522989_523418_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_000829818.1\|523433_523826_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_135801240.1\|523883_524168_+	hypothetical protein	NA	NA	NA	NA
WP_002918467.1\|524137_524776_+	stringent starvation protein A	NA	NA	NA	NA
WP_002918465.1\|524779_525274_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.5e-26	54.8

DBSCAN-SWA_2

1960907 : 2017174

Staphylococcus_phage(20.0%)

plate,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032425077.1\|1960907_1961654_+\|protease	proteasome-type protease	NA	NA	NA	NA
WP_048289971.1\|1962065_1963079_+	fatty acid desaturase	NA	NA	NA	NA
WP_004145488.1\|1963910_1964033_-	nitrilotriacetate monooxygenase	NA	NA	NA	NA
WP_023286625.1\|1964650_1965592_+	transcriptional regulator TdcA	NA	NA	NA	NA
WP_002910762.1\|1965685_1966675_+	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA	NA	NA	NA
WP_004145486.1\|1966700_1968032_+	threonine/serine transporter TdcC	NA	NA	NA	NA
WP_032425074.1\|1968059_1969268_+	propionate kinase	NA	NA	NA	NA
WP_032425474.1\|1969296_1971591_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	7.4e-158	41.7
WP_060614334.1\|1972021_1973137_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004175489.1\|1973246_1974161_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_060614333.1\|1974170_1975457_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_032425073.1\|1975453_1976329_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	9.5e-05	41.5
WP_004175491.1\|1976325_1977045_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-11	26.0
WP_002910720.1\|1977050_1977944_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004180410.1\|1978227_1979871_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	5.7e-136	50.4
WP_002910717.1\|1979920_1980397_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020801827.1\|1980495_1981422_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_032425072.1\|1981725_1983021_+	MFS transporter	Q6JIH2	Burkholderia_virus	7.4e-62	36.8
WP_004175495.1\|1983035_1983842_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_020801945.1\|1983816_1984716_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002910657.1\|1984825_1985308_-	cold shock domain-containing protein	NA	NA	NA	NA
WP_004197491.1\|1985498_1986197_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	2.6e-05	27.2
WP_004899028.1\|1986222_1986807_-	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_002910650.1\|1986876_1987206_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_004899025.1\|1987774_1989115_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004184632.1\|1989111_1989765_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_032425071.1\|1989768_1991466_+	OmpA family protein	NA	NA	NA	NA
WP_032425070.1\|1991924_1994411_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_032425069.1\|1994434_1995766_+	S-type Pyocin	NA	NA	NA	NA
WP_032425473.1\|1995810_1996734_-\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	2.3e-166	92.8
WP_032425068.1\|1996855_1997365_+	hypothetical protein	NA	NA	NA	NA
WP_002910591.1\|1997361_1997868_+	hypothetical protein	NA	NA	NA	NA
WP_060614320.1\|1998104_1998614_+	hypothetical protein	NA	NA	NA	NA
WP_032425067.1\|1998907_2000263_+	S-type Pyocin	NA	NA	NA	NA
WP_004200304.1\|2000263_2000773_+	hypothetical protein	NA	NA	NA	NA
WP_015958632.1\|2000769_2001276_+	hypothetical protein	NA	NA	NA	NA
WP_002910549.1\|2001321_2001552_+	hypothetical protein	NA	NA	NA	NA
WP_023317012.1\|2001575_2002766_+	hypothetical protein	NA	NA	NA	NA
WP_015958629.1\|2002789_2003095_+	hypothetical protein	NA	NA	NA	NA
WP_060614315.1\|2003116_2004010_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7H6	Microcystis_virus	1.1e-13	30.5
WP_016946122.1\|2004193_2005087_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	1.7e-12	27.3
WP_004184615.1\|2005262_2006156_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	2.2e-12	27.1
WP_004184614.1\|2007356_2007698_+	hypothetical protein	NA	NA	NA	NA
WP_004227463.1\|2007886_2008144_+	hypothetical protein	NA	NA	NA	NA
WP_002910497.1\|2008441_2008708_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_032411808.1\|2009857_2013268_+	type VI secretion protein VasK	NA	NA	NA	NA
WP_099595213.1\|2013401_2015165_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_060614316.1\|2015164_2016211_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_021314026.1\|2016185_2016728_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004175538.1\|2016730_2017174_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_3

2691415 : 2702302

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004151613.1\|2691415_2694523_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
WP_004151612.1\|2694577_2695843_+	MFS transporter	NA	NA	NA	NA
WP_001620097.1\|2695873_2696962_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_002904006.1\|2697048_2697309_-	hypothetical protein	A0A077SK33	Escherichia_phage	3.5e-40	97.7
WP_004176269.1\|2697606_2698467_+	class A broad-spectrum beta-lactamase SHV-11	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002210513.1\|2698487_2699249_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004151610.1\|2699509_2700412_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	7.7e-159	99.3
WP_004151609.1\|2700423_2701689_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	6.6e-233	99.5
WP_002210516.1\|2701681_2702302_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_4

2930508 : 3022744

109

uncultured_Caudovirales_phage(26.56%)

integrase,terminase,transposase

attL 2921137:2921154|attR 3031184:3031201

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2921137:2921154	attL	NA	NA	NA	NA
WP_004152576.1\|2930508_2931375_-	hypothetical protein	A0A2H4IYR0	uncultured_Caudovirales_phage	1.9e-34	64.5
WP_004152575.1\|2931374_2932148_-	DUF2612 domain-containing protein	A0A2H4J1A9	uncultured_Caudovirales_phage	2.8e-77	54.4
WP_004152574.1\|2932144_2933341_-	hypothetical protein	A0A0M4RD32	Salmonella_phage	3.9e-158	72.9
WP_004152573.1\|2933340_2933694_-	hypothetical protein	A0A2H4J629	uncultured_Caudovirales_phage	2.3e-50	80.3
WP_004152572.1\|2933695_2934349_-	hypothetical protein	A0A2H4J8H6	uncultured_Caudovirales_phage	1.0e-59	63.5
WP_004152571.1\|2934402_2934969_-	hypothetical protein	NA	NA	NA	NA
WP_004199301.1\|2935011_2935194_-	hypothetical protein	NA	NA	NA	NA
WP_004152570.1\|2935243_2935585_-	hypothetical protein	A0A2H4J1A5	uncultured_Caudovirales_phage	1.8e-23	46.6
WP_004152569.1\|2935584_2936607_-	hypothetical protein	A0A2H4J1B2	uncultured_Caudovirales_phage	9.2e-100	54.2
WP_004152568.1\|2936609_2936912_-	hypothetical protein	A0A2H4J495	uncultured_Caudovirales_phage	2.0e-26	55.2
WP_004152567.1\|2936912_2937512_-	hypothetical protein	A0A2H4J1B3	uncultured_Caudovirales_phage	9.9e-54	57.6
WP_004152566.1\|2937511_2939515_-	lytic transglycosylase domain-containing protein	A0A2H4J9N7	uncultured_Caudovirales_phage	1.2e-247	63.6
WP_004152565.1\|2939504_2939657_-	hypothetical protein	A0A2H4J1A2	uncultured_Caudovirales_phage	7.6e-19	88.0
WP_004152564.1\|2939692_2940118_-	hypothetical protein	A0A2H4J2V6	uncultured_Caudovirales_phage	2.6e-40	63.4
WP_004199809.1\|2940121_2940562_-	DUF3277 family protein	A0A0M5M1K6	Salmonella_phage	3.3e-62	80.1
WP_004152177.1\|2940572_2941718_-	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	6.3e-166	76.9
WP_004152176.1\|2941721_2942162_-	hypothetical protein	A0A2H4J1A0	uncultured_Caudovirales_phage	1.6e-40	51.7
WP_001116156.1\|2942256_2942643_-	hypothetical protein	A0A2H4J1A4	uncultured_Caudovirales_phage	1.1e-48	78.2
WP_000834982.1\|2942642_2943149_-	hypothetical protein	NA	NA	NA	NA
WP_000113538.1\|2943145_2943565_-	DUF4054 domain-containing protein	A0A0M5M3S2	Salmonella_phage	3.3e-40	60.7
WP_000725700.1\|2943533_2943815_-	hypothetical protein	NA	NA	NA	NA
WP_001132269.1\|2943854_2944796_-	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	1.7e-137	77.1
WP_000528476.1\|2944807_2945302_-	hypothetical protein	A0A2H4JHM9	uncultured_Caudovirales_phage	4.2e-50	62.7
WP_004199270.1\|2945305_2946508_-	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	2.6e-106	54.1
WP_004152174.1\|2946559_2947108_-	hypothetical protein	A0A0M4REK0	Salmonella_phage	3.0e-49	56.3
WP_004152173.1\|2947163_2948615_-	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	3.8e-192	68.8
WP_004152172.1\|2948852_2950253_-\|terminase	PBSX family phage terminase large subunit	A0A077KAW0	Edwardsiella_phage	9.4e-188	69.0
WP_004152171.1\|2950203_2950956_-	hypothetical protein	A0A077KBY7	Edwardsiella_phage	4.0e-12	66.0
WP_004152170.1\|2951057_2951378_-	hypothetical protein	NA	NA	NA	NA
WP_004153952.1\|2951612_2952002_-	lipase chaperone	A0A192Y6H8	Salmonella_phage	9.4e-21	49.2
WP_004152169.1\|2951998_2952529_-	lysozyme	K7PLY1	Enterobacteria_phage	2.7e-79	77.1
WP_004146526.1\|2952531_2952780_-	hypothetical protein	NA	NA	NA	NA
WP_004152167.1\|2953185_2953968_-	antitermination protein	F1C595	Cronobacter_phage	7.2e-113	76.8
WP_004198239.1\|2953964_2954441_-	hypothetical protein	A0A286N2Q1	Klebsiella_phage	1.8e-90	100.0
WP_004198233.1\|2954437_2955400_-	zinc-binding domain of primase-helicase family protein	A0A286N2Q0	Klebsiella_phage	4.8e-183	99.4
WP_004198228.1\|2955401_2957060_-	DEAD/DEAH box helicase	A0A286N2P9	Klebsiella_phage	0.0e+00	96.0
WP_004152162.1\|2957636_2957858_-	helix-turn-helix transcriptional regulator	A0A286S2C1	Klebsiella_phage	3.0e-32	100.0
WP_004152161.1\|2957955_2958624_+	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	2.4e-125	99.5
WP_004152160.1\|2958794_2959109_+	hypothetical protein	A0A286S1T9	Klebsiella_phage	1.0e-49	100.0
WP_004152159.1\|2959101_2959290_+	hypothetical protein	A0A286S1P8	Klebsiella_phage	4.6e-26	100.0
WP_004152158.1\|2959459_2959825_+	hypothetical protein	A0A286S1Q6	Klebsiella_phage	6.9e-58	99.2
WP_004152157.1\|2959817_2960072_+	hypothetical protein	A0A286SGR4	Klebsiella_phage	3.1e-41	97.6
WP_004177208.1\|2960043_2960262_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	6.6e-32	98.6
WP_004152156.1\|2960258_2960684_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	3.5e-53	77.9
WP_004152155.1\|2960680_2960875_+	hypothetical protein	NA	NA	NA	NA
WP_004152154.1\|2960871_2961699_+	hypothetical protein	Q8W654	Enterobacteria_phage	5.5e-111	84.0
WP_004152153.1\|2961803_2962322_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.7e-94	98.8
WP_004154298.1\|2962327_2963038_+	DNA-binding protein	A0A286S260	Klebsiella_phage	2.1e-111	88.3
WP_004152151.1\|2963027_2963252_+	hypothetical protein	A0A286S2B3	Klebsiella_phage	3.1e-29	89.2
WP_004152150.1\|2963248_2963461_+	hypothetical protein	A0A286S2B6	Klebsiella_phage	3.4e-33	98.6
WP_004152149.1\|2963457_2963937_+	hypothetical protein	NA	NA	NA	NA
WP_004152148.1\|2964115_2964358_+	hypothetical protein	A0A0M4RTZ2	Salmonella_phage	2.2e-20	73.8
WP_004152147.1\|2964338_2965520_-\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	5.6e-202	84.2
WP_016197745.1\|2965716_2966265_+	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_004152145.1\|2966463_2967996_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	1.1e-21	30.0
WP_004152144.1\|2968212_2968974_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-20	32.5
WP_004152143.1\|2969082_2969997_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004176439.1\|2970297_2970486_+	hypothetical protein	NA	NA	NA	NA
WP_004152142.1\|2970556_2970865_-	ATP-binding protein	NA	NA	NA	NA
WP_004152141.1\|2971032_2971902_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.7e-50	42.1
WP_004218007.1\|2971980_2973183_-	MFS transporter	NA	NA	NA	NA
WP_004152139.1\|2973255_2974392_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_004152138.1\|2974564_2975449_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004152137.1\|2975573_2976407_-	hypothetical protein	NA	NA	NA	NA
WP_004152136.1\|2976637_2977024_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_004152135.1\|2977191_2978808_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004152134.1\|2978993_2979701_+	murein tripeptide amidase MpaA	NA	NA	NA	NA
WP_004152133.1\|2979697_2980663_-	L-Ala-D/L-Glu epimerase	NA	NA	NA	NA
WP_004152131.1\|2980765_2981272_+	thiol peroxidase	NA	NA	NA	NA
WP_085666574.1\|2981342_2982365_-	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_002901979.1\|2982496_2984038_-	transcriptional regulator TyrR	NA	NA	NA	NA
WP_002901977.1\|2984210_2985524_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_071531198.1\|2985655_2986537_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004152127.1\|2986626_2987688_-	TIGR01620 family protein	NA	NA	NA	NA
WP_002901917.1\|2987684_2989082_-	YcjX family protein	NA	NA	NA	NA
WP_002901915.1\|2989184_2989403_-	phage shock protein PspD	NA	NA	NA	NA
WP_002901913.1\|2989431_2989791_-	envelope stress response membrane protein PspC	NA	NA	NA	NA
WP_002901911.1\|2989790_2990015_-	envelope stress response membrane protein PspB	NA	NA	NA	NA
WP_002901908.1\|2990070_2990739_-	phage shock protein PspA	NA	NA	NA	NA
WP_002901905.1\|2990906_2991881_+	phage shock protein operon transcriptional activator	NA	NA	NA	NA
WP_002901901.1\|2991871_2993263_-	MFS transporter	NA	NA	NA	NA
WP_002901900.1\|2993288_2994458_-	amidohydrolase	NA	NA	NA	NA
WP_004152126.1\|2994629_2996939_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004171423.1\|2996917_2997748_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004152124.1\|2997858_2998764_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002901817.1\|2999097_3000741_+	peptide ABC transporter substrate-binding protein SapA	NA	NA	NA	NA
WP_002901816.1\|3000737_3001703_+	peptide ABC transporter permease SapB	NA	NA	NA	NA
WP_002901815.1\|3001907_3002579_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	4.5e-79	59.6
WP_071531199.1\|3002765_3003593_+	FRG domain-containing protein	A0A1S6KZX9	Salmonella_phage	8.4e-19	30.2
WP_002901813.1\|3003668_3004934_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	9.6e-208	82.7
WP_002901812.1\|3004935_3005355_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.4e-35	57.5
WP_004152765.1\|3005434_3006919_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004152765.1\|3007344_3008829_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004152776.1\|3009726_3010149_-	hypothetical protein	K7P834	Enterobacteria_phage	3.6e-26	45.3
WP_001067855.1\|3010741_3011446_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001389365.1\|3011622_3012387_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_004152787.1\|3012770_3012911_+	hypothetical protein	NA	NA	NA	NA
WP_000376623.1\|3012893_3013394_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000259031.1\|3013521_3014361_-	sulfonamide-resistant dihydropteroate synthase Sul1	NA	NA	NA	NA
WP_000679427.1\|3014354_3014702_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001261740.1\|3014865_3015657_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_015057121.1\|3015802_3016762_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.7e-47	40.5
WP_001067855.1\|3016652_3017357_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_081541247.1\|3017415_3017820_+	regulator	M9NYX4	Enterobacteria_phage	2.6e-58	78.9
WP_004151899.1\|3017816_3018479_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-105	84.6
WP_004153574.1\|3018686_3019874_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	1.1e-120	52.4
WP_004151901.1\|3020050_3020941_+	peptide ABC transporter permease SapC	NA	NA	NA	NA
WP_004140266.1\|3020940_3021933_+	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	3.0e-07	27.2
WP_004140269.1\|3021934_3022744_+	peptide ABC transporter ATP-binding protein SapF	A0A2H4PQG7	Staphylococcus_phage	2.1e-14	28.9
3031184:3031201	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3399978 : 3494590

Salmonella_phage(57.63%)

tail,plate,tRNA,transposase,lysis,terminase,protease,capsid,head,portal,integrase

attL 3457165:3457183|attR 3494665:3494683

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002898139.1\|3399978_3401271_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	7.3e-94	44.7
WP_002898137.1\|3401361_3402705_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	7.3e-81	40.8
WP_002898132.1\|3402713_3403325_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_004150846.1\|3403447_3407701_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	5.2e-88	49.2
WP_000228469.1\|3407836_3408331_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_004141839.1\|3408836_3409832_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	3.3e-62	44.0
WP_002898017.1\|3409946_3411713_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	2.3e-21	25.9
WP_004150847.1\|3411713_3413435_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
WP_002898014.1\|3413479_3414181_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3414534_3414753_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002896522.1\|3414873_3417153_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_002896520.1\|3417183_3417501_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|3417826_3418048_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_004150848.1\|3418124_3420065_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_002896440.1\|3420061_3421177_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_000608644.1\|3421479_3422742_-\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_002896437.1\|3422984_3424643_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_002896434.1\|3425062_3425758_+	aquaporin Z	NA	NA	NA	NA
WP_004147773.1\|3425873_3426773_+	lysine exporter LysO family protein	NA	NA	NA	NA
WP_002896412.1\|3426916_3428569_+	hydroxylamine reductase	NA	NA	NA	NA
WP_002896410.1\|3428579_3429548_+	NADH oxidoreductase	NA	NA	NA	NA
WP_002896408.1\|3429759_3430194_-	DoxX family protein	NA	NA	NA	NA
WP_002896406.1\|3430345_3432064_+	ubiquinone-dependent pyruvate dehydrogenase	NA	NA	NA	NA
WP_002896404.1\|3432102_3433104_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_002896401.1\|3433114_3434557_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002896399.1\|3434644_3435658_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_002896397.1\|3435654_3436485_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	4.1e-05	31.6
WP_004150851.1\|3436516_3437656_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_002896394.1\|3438533_3439049_+	lipoprotein	NA	NA	NA	NA
WP_002896392.1\|3439275_3440004_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	1.2e-29	37.1
WP_002896390.1\|3440024_3440756_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896386.1\|3440762_3441479_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_004150852.1\|3441478_3442147_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_002896384.1\|3442330_3443062_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896382.1\|3443104_3444577_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	7.9e-28	31.8
WP_002896380.1\|3444573_3445290_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.1e-34	36.9
WP_002896378.1\|3445368_3446496_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A2K5B251	Erysipelothrix_phage	1.3e-19	25.6
WP_002896376.1\|3446537_3447026_-	DUF2593 family protein	NA	NA	NA	NA
WP_002896372.1\|3447083_3447929_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_002896371.1\|3447925_3448879_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_002896370.1\|3448889_3450023_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	2.2e-30	34.9
WP_002896368.1\|3450186_3451299_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_002896365.1\|3451647_3452127_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_002896363.1\|3452215_3453118_-	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	2.0e-34	35.3
WP_002896354.1\|3453939_3454227_-	YbjC family protein	NA	NA	NA	NA
WP_002896352.1\|3454429_3454693_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	1.6e-27	73.1
WP_002896351.1\|3454699_3455083_-	membrane protein	NA	NA	NA	NA
WP_004179131.1\|3455349_3457035_+	aspartate:alanine antiporter	NA	NA	NA	NA
3457165:3457183	attL	NA	NA	NA	NA
WP_000972391.1\|3457254_3457473_-	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	7.5e-20	69.0
WP_002896225.1\|3457564_3458665_-	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	4.9e-176	87.4
WP_002896224.1\|3458661_3459147_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	7.2e-63	75.6
WP_002896222.1\|3459143_3461771_-\|tail	phage tail tape measure protein	E5FFG5	Burkholderia_phage	5.6e-117	42.0
WP_002896220.1\|3461763_3461883_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.2e-13	87.2
WP_002896204.1\|3461897_3462197_-\|tail	phage tail assembly protein	E5G6P9	Salmonella_phage	3.7e-33	79.0
WP_002896201.1\|3462249_3462765_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	1.3e-81	85.4
WP_002896193.1\|3462774_3463947_-\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.9e-210	93.3
WP_002896191.1\|3464085_3465162_-\|tail	phage tail protein	Q37842	Escherichia_phage	1.2e-25	44.8
WP_002896188.1\|3465191_3465395_-	hypothetical protein	NA	NA	NA	NA
WP_002896186.1\|3465391_3466123_-	hypothetical protein	NA	NA	NA	NA
WP_004152882.1\|3466126_3469078_-	hypothetical protein	A0A2H4N7A3	Pectobacterium_phage	1.2e-06	50.9
WP_004150856.1\|3469079_3469679_-\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.3e-58	60.5
WP_002896182.1\|3469671_3470580_-\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	7.6e-106	66.9
WP_002896179.1\|3470566_3470929_-\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	5.8e-49	84.7
WP_002896177.1\|3470925_3471498_-\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	4.7e-77	72.3
WP_004150857.1\|3471592_3472285_+	hypothetical protein	NA	NA	NA	NA
WP_002896175.1\|3472281_3472728_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.2e-50	71.2
WP_002896172.1\|3472720_3473152_-\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	9.9e-64	82.5
WP_002896168.1\|3473247_3473676_-\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	9.6e-51	77.9
WP_002896163.1\|3473672_3474056_-	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	2.1e-17	42.0
WP_002896161.1\|3474060_3474570_-	lysozyme	E5G6N1	Salmonella_phage	2.1e-81	83.4
WP_002896158.1\|3474550_3474766_-	hypothetical protein	E5G6N0	Salmonella_phage	3.6e-30	90.1
WP_002896155.1\|3474769_3474973_-\|tail	tail protein X	A0A1S6KZY4	Salmonella_phage	1.3e-29	88.1
WP_002896151.1\|3474972_3475437_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	8.4e-77	89.0
WP_000059191.1\|3475532_3476183_-\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
WP_002895972.1\|3476186_3477245_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	1.1e-180	93.1
WP_002895967.1\|3477261_3478095_-\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	6.3e-123	88.8
WP_004150858.1\|3478237_3480004_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.0
WP_002895959.1\|3480003_3481029_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	7.6e-171	86.7
WP_004199124.1\|3481090_3482833_-	AIPR family protein	NA	NA	NA	NA
WP_000700647.1\|3483108_3483786_-	hypothetical protein	NA	NA	NA	NA
WP_001217575.1\|3483900_3484134_-	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_001154434.1\|3484144_3484333_-	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_004150862.1\|3484486_3486901_-	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.5
WP_004150863.1\|3486897_3487755_-	DNA adenine methylase	E5G6L8	Salmonella_phage	2.0e-156	95.4
WP_000752622.1\|3487751_3487979_-	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	6.0e-36	98.7
WP_004150864.1\|3487978_3488212_-	DUF2732 family protein	E5G6L6	Salmonella_phage	4.1e-32	96.1
WP_000963473.1\|3488279_3488621_-	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	4.6e-56	99.1
WP_000956179.1\|3488584_3488785_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	1.6e-32	97.0
WP_000460893.1\|3488792_3489302_-	phage regulatory CII family protein	E5G6L3	Salmonella_phage	5.8e-87	98.8
WP_000188448.1\|3489334_3489556_-	hypothetical protein	NA	NA	NA	NA
WP_004152885.1\|3489701_3490580_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.7e-30	39.9
WP_004150866.1\|3490591_3491536_+	hypothetical protein	NA	NA	NA	NA
WP_004152765.1\|3491634_3493119_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004151720.1\|3493537_3494590_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.0e-106	57.0
3494665:3494683	attR	NA	NA	NA	NA

DBSCAN-SWA_6

4146844 : 4158498

Enterobacteria_phage(70.0%)

integrase

attL 4147294:4147308|attR 4170351:4170365

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004144574.1\|4146844_4147948_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-62	40.5
4147294:4147308	attL	NA	NA	NA	NA
WP_002889940.1\|4147958_4149212_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	8.9e-89	44.9
WP_002889938.1\|4149564_4150755_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	6.4e-145	62.7
WP_004152029.1\|4150742_4151693_+	AAA family ATPase	A0A1X9IGI7	Lactococcus_phage	1.2e-13	27.1
WP_004152979.1\|4151692_4152118_+	hypothetical protein	NA	NA	NA	NA
WP_002889930.1\|4152686_4153253_-	phage polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.5e-59	64.3
WP_002889919.1\|4153270_4153516_-	hypothetical protein	Q7M294	Enterobacteria_phage	1.9e-19	58.0
WP_002889917.1\|4153512_4154250_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	9.0e-73	60.7
WP_002889915.1\|4154791_4155058_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	2.6e-30	71.6
WP_024940872.1\|4155054_4155612_+	ash family protein	Q7M2A7	Enterobacteria_phage	1.8e-33	70.4
WP_002889911.1\|4155608_4155836_+	hypothetical protein	NA	NA	NA	NA
WP_002889897.1\|4155832_4156153_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_002889890.1\|4156164_4158498_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	82.2
4170351:4170365	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP024538

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

6364 : 67876

Escherichia_phage(44.83%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000227969.1\|6364_7441_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_001067855.1\|8153_8858_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000509965.1\|9394_10000_+	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	9.4e-20	35.3
WP_001067855.1\|10601_11306_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_063840321.1\|11449_12004_+	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
WP_001334766.1\|12134_12965_+	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_001067855.1\|13596_14301_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000557452.1\|14407_15268_+	aminoglycoside N-acetyltransferase AAC(3)-IIa	NA	NA	NA	NA
WP_002063889.1\|15280_15823_+	AAA family ATPase	NA	NA	NA	NA
WP_001067855.1\|17016_17721_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001067855.1\|18998_19703_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000368714.1\|20790_21996_+	ParA family protein	A0A077SL49	Escherichia_phage	2.4e-163	69.6
WP_012600007.1\|21992_22970_+	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	2.6e-88	54.4
WP_004118291.1\|23051_24323_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	4.9e-151	63.3
WP_000776034.1\|24322_24754_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.6e-29	53.3
WP_004152765.1\|25162_26647_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_001776120.1\|27116_27548_+	hypothetical protein	NA	NA	NA	NA
WP_001776119.1\|27580_28108_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.7e-21	39.5
WP_001166628.1\|28367_28823_-	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_004200999.1\|28894_29260_+	mercuric ion transporter MerT	NA	NA	NA	NA
WP_000732275.1\|29275_29551_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_000522996.1\|29578_30004_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000209296.1\|30042_31728_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-39	29.1
WP_001277466.1\|31745_32111_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_001087807.1\|32107_32344_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_050558936.1\|32327_32411_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|32479_33184_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_014386481.1\|34056_34701_-	quinolone resistance pentapeptide repeat protein QnrB1	NA	NA	NA	NA
WP_087759376.1\|39683_40804_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.0e-52	43.2
WP_020324562.1\|40901_41606_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	9.9e-138	99.6
WP_071549088.1\|41630_42143_+	restriction endonuclease	NA	NA	NA	NA
WP_001749967.1\|42147_42354_+	hypothetical protein	NA	NA	NA	NA
WP_001288432.1\|42735_44169_+	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	7.0e-106	50.6
WP_004098817.1\|44202_45417_-	type II site-specific deoxyribonuclease	E5E3X4	Burkholderia_phage	1.2e-34	42.5
WP_001389365.1\|45677_46442_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_001144737.1\|46584_46851_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_001067855.1\|47385_48090_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004201232.1\|48886_49573_+	NYN domain-containing protein	NA	NA	NA	NA
WP_004201234.1\|49710_50448_+	hypothetical protein	NA	NA	NA	NA
WP_004201235.1\|50967_52437_-	HNH endonuclease	G0X580	Salmonella_phage	5.5e-21	51.3
WP_001067855.1\|52682_53387_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001393253.1\|55708_56041_+	cupin fold metalloprotein, WbuC family	NA	NA	NA	NA
WP_000239590.1\|56087_56963_-	class A extended-spectrum beta-lactamase CTX-M-15	A0A1B0VBP7	Salmonella_phage	1.1e-125	82.4
WP_000608644.1\|57218_58481_-\|transposase	IS1380-like element ISEc9 family transposase	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
WP_001235713.1\|59044_59602_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_000027057.1\|59784_60645_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001120891.1\|60854_61394_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000480968.1\|61365_62202_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001082319.1\|62201_63005_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
WP_001043260.1\|63065_63881_-	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
WP_000954592.1\|64210_64387_+	DUF4102 domain-containing protein	T1S9J3	Salmonella_phage	1.0e-06	68.6
WP_000427619.1\|64568_65573_-\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_001067855.1\|67171_67876_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP024536

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

24187 : 66066

Escherichia_phage(35.71%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_125551036.1\|24187_24884_+\|transposase	IS1 family transposase	A0A077SLN4	Escherichia_phage	4.7e-132	98.7
WP_000056203.1\|25024_25243_+	hypothetical protein	NA	NA	NA	NA
WP_001909178.1\|25612_25999_+	type IV secretion system protein	NA	NA	NA	NA
WP_019706045.1\|26072_26894_+	TrbG/VirB9 family P-type conjugative transfer protein	NA	NA	NA	NA
WP_000101710.1\|26893_28054_+	TrbI/VirB10 family protein	NA	NA	NA	NA
WP_000128596.1\|28095_29091_+	Flp pilus assembly complex ATPase component	NA	NA	NA	NA
WP_000792636.1\|29090_29624_+	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	5.8e-21	33.9
WP_002210549.1\|30595_30937_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	7.3e-62	100.0
WP_001067855.1\|30973_31678_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001044210.1\|31683_31824_+	hypothetical protein	NA	NA	NA	NA
WP_001366550.1\|32309_33047_+	recombinase family protein	NA	NA	NA	NA
WP_000743213.1\|33043_33268_+	hypothetical protein	NA	NA	NA	NA
WP_000338945.1\|33366_33678_+	hypothetical protein	NA	NA	NA	NA
WP_001151304.1\|33851_34637_+	ParA family protein	A0A1X9IGI7	Lactococcus_phage	6.1e-11	26.4
WP_001207227.1\|34640_35822_+	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	2.4e-11	28.7
WP_000703827.1\|35870_36143_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_099595285.1\|36878_38378_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.5e-10	26.7
WP_099595287.1\|38364_39105_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	2.7e-32	36.9
WP_000939033.1\|39325_39469_-	hypothetical protein	NA	NA	NA	NA
WP_001125905.1\|39787_40165_+	hypothetical protein	A0A2H4P7P5	Pseudomonas_phage	2.2e-22	49.6
WP_000044824.1\|40157_40439_+	hypothetical protein	NA	NA	NA	NA
WP_000344151.1\|40413_41088_+	thymidylate kinase	NA	NA	NA	NA
WP_005507681.1\|41155_41587_+	hypothetical protein	NA	NA	NA	NA
WP_000348669.1\|41571_41904_+	hypothetical protein	NA	NA	NA	NA
WP_000647189.1\|41912_42413_+	hypothetical protein	I3UMJ0	Colwellia_phage	1.7e-19	43.3
WP_000936896.1\|42416_43844_+	DNA cytosine methyltransferase	NA	NA	NA	NA
WP_000268551.1\|43843_44500_+	hypothetical protein	NA	NA	NA	NA
WP_000362482.1\|44705_44924_+	hypothetical protein	NA	NA	NA	NA
WP_000464631.1\|45017_45635_+	hypothetical protein	NA	NA	NA	NA
WP_000542259.1\|45846_46146_+	hypothetical protein	A0A0K1LLW2	Caulobacter_phage	2.1e-20	55.4
WP_000468105.1\|46237_46726_-	hypothetical protein	NA	NA	NA	NA
WP_000366822.1\|46740_48933_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	1.7e-42	29.2
WP_001191892.1\|48932_49166_-	hypothetical protein	NA	NA	NA	NA
WP_001249396.1\|49147_49765_-	hypothetical protein	NA	NA	NA	NA
WP_085955245.1\|52549_53742_-\|transposase	IS3-like element ISKpn18 family transposase	U5P429	Shigella_phage	3.5e-50	43.5
WP_000178856.1\|54213_56079_+	conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_000332866.1\|56089_56674_+	hypothetical protein	NA	NA	NA	NA
WP_000743450.1\|56630_57260_+	DUF4400 domain-containing protein	NA	NA	NA	NA
WP_000122506.1\|57269_57716_+	hypothetical protein	NA	NA	NA	NA
WP_000869261.1\|57725_58103_+	hypothetical protein	NA	NA	NA	NA
WP_001231463.1\|58102_58765_+	hypothetical protein	NA	NA	NA	NA
WP_000509509.1\|59088_59466_+	hypothetical protein	NA	NA	NA	NA
WP_000805625.1\|59610_59892_+	type IV conjugative transfer system protein TraL	NA	NA	NA	NA
WP_001049716.1\|59888_60515_+	hypothetical protein	NA	NA	NA	NA
WP_000794249.1\|60498_61416_+	conjugal transfer protein TraK	NA	NA	NA	NA
WP_000595749.1\|61412_62729_+	conjugal transfer protein TraB	NA	NA	NA	NA
WP_000793435.1\|62725_63304_+	type IV conjugative transfer system lipoprotein TraV	NA	NA	NA	NA
WP_000479535.1\|63307_63700_+	hypothetical protein	NA	NA	NA	NA
WP_087759376.1\|64946_66066_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.0e-52	43.2

DBSCAN-SWA_2

110090 : 183446

Escherichia_phage(14.29%)

integrase,transposase

attL 121682:121703|attR 163699:163720

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099725713.1\|110090_111137_+\|transposase	IS481-like element ISKpn28 family transposase	NA	NA	NA	NA
WP_001083725.1\|111393_111891_+	trimethoprim-resistant dihydrofolate reductase DfrA12	A0A0A0PL85	Bacillus_phage	7.5e-23	40.9
WP_001336345.1\|112002_112293_+	DUF1010 domain-containing protein	NA	NA	NA	NA
WP_001206356.1\|112298_113090_+	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NA	NA	NA	NA
WP_000679427.1\|113253_113601_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|113594_114434_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_004883563.1\|114561_114834_+	hypothetical protein	NA	NA	NA	NA
WP_022652300.1\|115015_115969_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_022652302.1\|116589_117300_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-31	37.7
WP_022652303.1\|117301_118507_-	ABC transporter permease	NA	NA	NA	NA
WP_022652304.1\|118503_119655_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004393990.1\|119651_120260_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_032430842.1\|120447_121401_+\|transposase	IS110 family transposase	NA	NA	NA	NA
121682:121703	attL	NA	NA	NA	NA
WP_000493286.1\|121819_122149_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	2.4e-09	44.2
WP_000780222.1\|122129_122411_+	helix-turn-helix transcriptional regulator	A0A2I6TC97	Escherichia_phage	1.3e-08	38.0
WP_016947617.1\|122688_123669_+\|transposase	IS5-like element ISKpn26 family transposase	A0A077SK28	Escherichia_phage	6.8e-185	98.8
WP_087893729.1\|123974_125248_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	2.8e-146	81.7
WP_001752509.1\|125321_125822_-	non-heme ferritin-like protein	NA	NA	NA	NA
WP_001067855.1\|126148_126853_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000935452.1\|126899_128204_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_000204520.1\|128242_128950_-	EAL domain-containing protein	NA	NA	NA	NA
WP_000993386.1\|128946_129183_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001277456.1\|129179_129542_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_000105636.1\|129559_131254_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	8.8e-39	27.6
WP_001447540.1\|131305_131728_-	organomercurial transporter MerC	NA	NA	NA	NA
WP_000732292.1\|131763_132039_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294663.1\|132052_132403_-	mercuric transport protein MerT	NA	NA	NA	NA
WP_000429836.1\|132474_132909_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_047359309.1\|132987_133992_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_099595309.1\|134800_135052_+	hypothetical protein	NA	NA	NA	NA
WP_099595311.1\|135732_135990_-	hypothetical protein	NA	NA	NA	NA
WP_043006371.1\|136564_136849_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_008652077.1\|136873_137383_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_034053978.1\|137468_137957_+	redoxin domain-containing protein	NA	NA	NA	NA
WP_074423286.1\|137961_139494_+	YdiU family protein	A0A075BSJ0	Microcystis_phage	4.1e-51	32.6
WP_034054008.1\|140061_140502_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_004099020.1\|141961_142333_+	hypothetical protein	NA	NA	NA	NA
WP_000844627.1\|143946_144189_+\|transposase	transposase	NA	NA	NA	NA
WP_000470728.1\|144220_144898_-	tetracycline resistance transcriptional repressor TetR(A)	NA	NA	NA	NA
WP_000804064.1\|144976_146176_+	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_000427620.1\|146779_147784_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_000414383.1\|147883_148318_-	mercury resistance transcriptional regulator MerR	NA	NA	NA	NA
WP_001294666.1\|148389_148740_+	mercuric transport protein MerT	NA	NA	NA	NA
WP_000732290.1\|148755_149031_+	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_000149288.1\|149102_150788_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.1e-38	27.9
WP_000761850.1\|150802_151441_+	organomercurial lyase MerB	NA	NA	NA	NA
WP_000995361.1\|151552_151918_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_001087810.1\|151914_152151_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001276635.1\|152147_153137_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_053821786.1\|153266_153827_+	recombinase family protein	A0A1B0V7I5	Salmonella_phage	1.3e-50	87.9
WP_053821785.1\|153829_156796_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.2
WP_000427620.1\|156874_157879_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_000787563.1\|158983_159256_+	MafI family immunity protein	NA	NA	NA	NA
WP_125551039.1\|159260_159503_+	hypothetical protein	NA	NA	NA	NA
WP_000243483.1\|159514_159850_+	hypothetical protein	NA	NA	NA	NA
WP_000791469.1\|160016_160469_+	hypothetical protein	NA	NA	NA	NA
WP_000278322.1\|160484_161087_-	hypothetical protein	NA	NA	NA	NA
WP_000243801.1\|161309_161630_+	hypothetical protein	NA	NA	NA	NA
WP_000949433.1\|161928_162465_+	hypothetical protein	NA	NA	NA	NA
WP_000543934.1\|162467_163478_+\|integrase	tyrosine-type recombinase/integrase	A0A0K0N6I5	Gordonia_phage	3.1e-07	31.9
WP_000027057.1\|163834_164695_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
163699:163720	attR	NA	NA	NA	NA
WP_001235713.1\|164877_165435_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_001143760.1\|165598_168604_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
WP_052952388.1\|168725_169307_+	3'-5' exonuclease	A0A1S6L012	Salmonella_phage	2.3e-23	35.2
WP_000139717.1\|169303_169795_+	hypothetical protein	NA	NA	NA	NA
WP_001097010.1\|170121_170997_+	DNA replication terminus site-binding protein	NA	NA	NA	NA
WP_000101568.1\|171158_172199_+	DNA-binding protein	NA	NA	NA	NA
WP_000811656.1\|172485_173997_+	ATP-dependent helicase	A0A2D1GN12	Pseudoalteromonas_phage	3.6e-44	30.7
WP_001326396.1\|174107_175148_+	conjugal transfer protein TraF	NA	NA	NA	NA
WP_000256129.1\|175149_176583_+	conjugal transfer protein TraH	NA	NA	NA	NA
WP_000534551.1\|176595_180210_+	conjugal transfer protein TraG	NA	NA	NA	NA
WP_000683483.1\|180247_180610_-	hypothetical protein	NA	NA	NA	NA
WP_000356489.1\|181325_181598_+	nucleotide excision repair protein	A0A2H4J3B6	uncultured_Caudovirales_phage	1.3e-08	41.0
WP_000790610.1\|181597_182131_+	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_087759376.1\|182326_183446_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.0e-52	43.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP024537

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP024535

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP024538

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP024536

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection