CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020985	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6992 chromosome, complete genome	5 crisprs	WYL,cas3,DEDDh,csa3,DinG	0	4	7	0
NZ_CP020986	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6992 plasmid pA, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020985_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020985_1

521069-521320

Orphan

Consensus_repeat	Method
GGCGGGCTGGAAACGGTCAACGGCAGCATC	CRISPRCasFinder

4 spacers

WYL

The CRISPR arrays of NZ_CP020985_1

>merge|NZ_CP020985|1|521069-521320|CRISPRCasFinder
GGCGCTCTGGAAACGGTCAATGGCTCCATCGAGATCGGTGCCGGTGCGCAAACCAAGAACGTGGAAACCGTCAACGGCGGCATCCGCATCGGCGACAACGCGCGTACCGGGGGCGTGGAAACGGTCAACGGCTCGATCACGCTGGGCCAGAAGGTGATCGTGTCCGGCGGGCTGGAAACGGTCAACGGCAGCATCCTCGCCGAGCGCGGCAGCCAGATCAGTGGCGGGGTGGAAACGGTCAACGGCAGCATC

>NZ_CP020985|1|1|521069-521320|CRISPRCasFinder
GGCGCTCTGGAAACGGTCAATGGCTCCATC	GAGATCGGTGCCGGTGCGCAAACC
AAGAACGTGGAAACCGTCAACGGCGGCATC	CGCATCGGCGACAACGCGCGTACC
GGGGGCGTGGAAACGGTCAACGGCTCGATC	ACGCTGGGCCAGAAGGTGATCGTGTCC
GGCGGGCTGGAAACGGTCAACGGCAGCATC	CTCGCCGAGCGCGGCAGCCAGATCAGT
GGCGGGGTGGAAACGGTCAACGGCAGCATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020985.1\|WP_099803346.1\|533368_537841_-\|glutamate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236968
NZ_CP020985.1\|WP_099803337.1\|511814_512942_-\|PA0069-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|275263
NZ_CP020985.1\|WP_099803341.1\|524617_525751_-\|glycoside-hydrolase-family-5-protein	unknown	unknown	gnl\|CDD\|365907
NZ_CP020985.1\|WP_099803336.1\|510551_511277_+\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP020985.1\|WP_007971900.1\|513128_513830_-\|2OG-Fe(II)-oxygenase	unknown	unknown	gnl\|CDD\|379309
NZ_CP020985.1\|WP_042676190.1\|511325_511691_+\|DUF1330-domain-containing-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_003482177.1\|515655_516348_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NZ_CP020985.1\|WP_099803345.1\|531765_533247_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|273553
NZ_CP020985.1\|WP_099803338.1\|516775_517768_+\|D-2-hydroxyacid-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|240646
NZ_CP020985.1\|WP_099803340.1\|523879_524323_-\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|379323
NZ_CP020985.1\|WP_007968187.1\|514096_515437_-\|outer-membrane-protein-transport-protein	unknown	unknown	gnl\|CDD\|367457
NZ_CP020985.1\|WP_007968182.1\|517930_519454_-\|S41-family-peptidase	unknown	unknown	gnl\|CDD\|223864
NZ_CP020985.1\|WP_099803344.1\|530972_531251_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379735
NZ_CP020985.1\|WP_099804818.1\|519558_520794_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|227278
NZ_CP020985.1\|WP_057661749.1\|516455_516776_+\|DUF1820-family-protein	unknown	unknown	gnl\|CDD\|370154
NZ_CP020985.1\|WP_099803342.1\|526388_527441_-\|glycoside-hydrolase-family-5-protein	unknown	unknown	gnl\|CDD\|365907
NZ_CP020985.1\|WP_099803339.1\|521772_523569_+\|M28-family-peptidase	unknown	unknown	gnl\|CDD\|349910
NZ_CP020985.1\|WP_099803343.1\|528217_529291_-\|glycoside-hydrolase-family-5-protein	unknown	unknown	gnl\|CDD\|365907
NZ_CP020985.1\|WP_022557795.1\|529599_530658_+\|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176186
NZ_CP020985.1\|WP_089140640.1\|531326_531752_-\|DUF4279-domain-containing-protein	unknown	unknown	gnl\|CDD\|372913

Protein	Function_ID	Function_description	E-value
NZ_CP020985.1\|WP_099803346.1\|533368_537841_-\|glutamate-synthase-large-subunit	gnl\|CDD\|236968	PRK11750, gltB, glutamate synthase subunit alpha; Provisional.	0
NZ_CP020985.1\|WP_099803337.1\|511814_512942_-\|PA0069-family-radical-SAM-protein	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	1.36327e-23
NZ_CP020985.1\|WP_099803341.1\|524617_525751_-\|glycoside-hydrolase-family-5-protein	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	3.65254e-57
NZ_CP020985.1\|WP_099803336.1\|510551_511277_+\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.28197e-54
NZ_CP020985.1\|WP_007971900.1\|513128_513830_-\|2OG-Fe(II)-oxygenase	gnl\|CDD\|379309	pfam13640, 2OG-FeII_Oxy_3, 2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily.	1.10927e-07
NZ_CP020985.1\|WP_003482177.1\|515655_516348_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	1.19314e-25
NZ_CP020985.1\|WP_099803345.1\|531765_533247_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|273553	TIGR01318, glutamate_synthase_small_subunit_gltD, glutamate synthase small subunit family protein, proteobacterial. This model represents one of three built for the NADPH-dependent or NADH-dependent glutamate synthase (EC 1.4.1.13 and 1.4.1.14, respectively) small subunit and homologs. TIGR01317 describes the small subunit (or equivalent region from longer forms) in eukaryotes, Gram-positive bacteria, and some other lineages, both NADH and NADPH-dependent. TIGR01316 describes a protein of similar length, from Archaea and a number of bacterial lineages, that forms glutamate synthase homotetramers without a large subunit. This model describes both glutatate synthase small subunit and closely related paralogs of unknown function from a number of gamma and alpha subdivision Proteobacteria, including E. coli.	0
NZ_CP020985.1\|WP_099803338.1\|516775_517768_+\|D-2-hydroxyacid-dehydrogenase-family-protein	gnl\|CDD\|240646	cd12169, PGDH_like_1, Putative D-3-Phosphoglycerate Dehydrogenases. Phosphoglycerate dehydrogenases (PGDHs) catalyze the initial step in the biosynthesis of L-serine from D-3-phosphoglycerate. PGDHs come in 3 distinct structural forms, with this first group being related to 2-hydroxy acid dehydrogenases, sharing structural similarity to formate and glycerate dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily, which also include groups such as L-alanine dehydrogenase and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. Many, not all, members of this family are dimeric.	1.27631e-143
NZ_CP020985.1\|WP_099803340.1\|523879_524323_-\|PepSY-domain-containing-protein	gnl\|CDD\|379323	pfam13670, PepSY_2, Peptidase propeptide and YPEB domain. This region is likely to have a protease inhibitory function (personal obs:C Yeats). The name is derived from Peptidase & Bacillus subtilis YPEB.	3.49103e-05
NZ_CP020985.1\|WP_007968187.1\|514096_515437_-\|outer-membrane-protein-transport-protein	gnl\|CDD\|367457	pfam03349, Toluene_X, Outer membrane protein transport protein (OMPP1/FadL/TodX). This family includes TodX from Pseudomonas putida F1 and TbuX from Ralstonia pickettii PKO1. These are membrane proteins of uncertain function that are involved in toluene catabolism. Related proteins involved in the degradation of similar aromatic hydrocarbons are also in this family, such as CymD. This family also includes FadL involved in translocation of long-chain fatty acids across the outer membrane. It is also a receptor for the bacteriophage T2.	1.79229e-134
NZ_CP020985.1\|WP_007968182.1\|517930_519454_-\|S41-family-peptidase	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	2.8025e-128
NZ_CP020985.1\|WP_099803344.1\|530972_531251_-\|hypothetical-protein	gnl\|CDD\|379735	pfam15594, Imm50, Immunity protein 50. A predicted immunity protein with an all-beta fold. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Tox-HHH or Ntox24 families.	0.00049414
NZ_CP020985.1\|WP_099804818.1\|519558_520794_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	6.52534e-91
NZ_CP020985.1\|WP_057661749.1\|516455_516776_+\|DUF1820-family-protein	gnl\|CDD\|370154	pfam08850, DUF1820, Domain of unknown function (DUF1820). This family includes small functionally uncharacterized proteins around 100 amino acids in length.	7.75601e-52
NZ_CP020985.1\|WP_099803342.1\|526388_527441_-\|glycoside-hydrolase-family-5-protein	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	2.40174e-59
NZ_CP020985.1\|WP_099803339.1\|521772_523569_+\|M28-family-peptidase	gnl\|CDD\|349910	cd05660, M28_like_PA, M28 Zn-peptidase containing a protease-associated (PA) domain insert. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. This subfamily is composed of uncharacterized proteins containing a protease-associated (PA) domain insert which may participate in substrate binding and/or promote conformational changes, influencing the stability and accessibility of the site to substrate.	1.07972e-122
NZ_CP020985.1\|WP_099803343.1\|528217_529291_-\|glycoside-hydrolase-family-5-protein	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	5.77615e-62
NZ_CP020985.1\|WP_022557795.1\|529599_530658_+\|NAD(P)-dependent-alcohol-dehydrogenase	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP020985.1\|WP_089140640.1\|531326_531752_-\|DUF4279-domain-containing-protein	gnl\|CDD\|372913	pfam14106, DUF4279, Domain of unknown function (DUF4279). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 134 and 145 amino acids in length.	4.80657e-09

>NZ_CP020985.1|WP_099804818.1|519558_520794_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MWLAVGVLACTLLGSMGASAQSQRETERKLQQLRDELKTISADRRELEGKRGTAAQQLRQADEKVAKTARALSETEAAMRAQEQHLSSLQQERAQLQRGLQSQRTQLAALLRAADQVGRNAPLKVLLSQDTVGDATRMLADHRYVQNARAQRIHALTTQLDALATVEQDIATRRQALDAARAQQKAQAATLQKDRSQQAATVAQLDDRYKQRAEREKAIGQDAKALEQLLANLRAAAAKAEAERRAAARRAAAEAAAQAKRSKTERSDRPGKTPPKVVANAPAPKVGGLSWPVAGNLLARFNATLPDGHTSKGVLIGAPKGATVTAVADGTVVFSDWMTGYGMILIVDHGNGYMSLYAHNDTLLRDAGASIKRGDAVAKVGSSGGQGVPALYFELRRNGQPVDPSSWLQRR
>NZ_CP020985.1|WP_007968182.1|517930_519454_-|S41-family-peptidase
MRVAVLSVALSLALFASPGWAQKAGPAAAQASADDPEANEAAVSKVPLDEIRRFVAVYNAVKQAYVDPVEDKKLMHAAVRGLLSDLDPHSTYFDKEDAEAFDEQATGAYDGIGVELLQQQDNTLKVIAPIDDTPAARAGIRAGDVIVAIDGKPIDASKAMEPLRGESGSKVVLTIMRDKTPKPFDVTLQRETIRVASVRSKLLEPGYGYIRISTFQADTGADFQKNLKQLQAGGKLRGLVLDLRSNPGGLLTSAVQVADDLLDKGNIVSTRGRISISDAKFDATPGDLLNGAPVVVLVDAGSASASEVLAGALRDNKRARIIGSRTFGKGSVQTVLPLDNGDSVKLTTARYYTPSGKSIQASGIVPDVLLAPEPQPGDADAPASLTDYSEATLPGHLRGDDEGEEGYSAGDVLPGDGPITEALAELKQPGAAAKAQAARKAKAQAAQKAKAAKTGAEPKPAAARPATTDKPRSAEPAGKAKPATAPAAPAEPVQPTPPADKPAEPVN
>NZ_CP020985.1|WP_099803338.1|516775_517768_+|D-2-hydroxyacid-dehydrogenase-family-protein
MRVVVPDDYQGAVARLPCLQQLQGHQVQVLGALDEALDARAACLADADALVLIRERTRVDAALLQRLPRLKLISQTGRVGAHVDVAACTALGVAVAEGVGSPVAPAELTWALILSASRRLADYQHALQQGRWQALGDPGLGRVLHGRTLGIWSYGRIGQRVAGFGRAFGMQVLVWGGEASCAQAARDGFAVAGSREELFERSDVLSLHRRLTAQTRHDITAQDLARMRDDALLVNTSRAELIAPGALLAALDAGRPAQAALDVFEHEPVLDPRDSLLRHVRVLATPHLGYVERDSYALYFDAAFDNVLAFAAGTPRNLVNPEVLATTQRV
>NZ_CP020985.1|WP_057661749.1|516455_516776_+|DUF1820-family-protein
MSKPLYKVTFLNHGKVYELYAREVTGSHLWGFNQIGELVFDVHDGLVVDPTEERLREEFGNTRTLHLPMQSIVRIEEVQKKGQSVIRDATTGDKVVTPFPSPIKPR
>NZ_CP020985.1|WP_003482177.1|515655_516348_+|rhomboid-family-intramembrane-serine-protease
MFVSLPSRKKPTPRWAVPLLFATVWLAYLWSISRPGEARNTLWLDWGALSSGVSNLGDWWATLRDGSVLRLFTALFLHADWSHLLGNLVFLLIFGLPAERILGPWRLLLLFLVGGAASNLAAIFAIGTPDRVIIGASGAVSALIGTYLALFPGAKLGVVLPLGVFLEFIRVPAPLLIGAWALLQVVFAYIGPAFGMVAWSAHIAGFVFGIVYGLYVRAAIARRLRKRHGF
>NZ_CP020985.1|WP_007968187.1|514096_515437_-|outer-membrane-protein-transport-protein
MSTASTLSRATLLAVGIAGVLAVGQAHGAAFQLKENSAKGLGRAFAGSGSAPDDASIIATNPAGMRQLDGRLFQADVSAISFSAKFQPDTAAYANGAPVSGGNGGDAGMIAPVPALYFHVPFGENDNMHLGTSLTVPFGFKTEYDRDWVGRYHGTKTELQAIDFNVAFSYDVNPYVSFGASVFAERLDIDLANAVDFGSVLAARRVPGFAPGSADGYSRIKGDSTEVGFTLGGLFSIDENTHIGFSYRSQVEHKITDGTADFTVPGSAAAVLSVAAPGTFVDTKGRATVKLPASATASFTHNVNEQWSIMADVTRTAWSKFDQVTVDFASNQPDSVLDFSYRDTTFASIGADYRLSDTVTLRGGLAYDQTPTTAEHRDVRVPDASRKWVSLGMSWRPSAQTEYNFGYTHLFTSDPTSDTRSATGDRLAGSYDVKGDVLAASINYKF
>NZ_CP020985.1|WP_007971900.1|513128_513830_-|2OG-Fe(II)-oxygenase
MSQPDFIQITDNAIAHEECVAIVQRMRQSQQLHPGRIGGGVFPDLKHSRDLRISGMAEWAEVENRLQQAVFEGVLTYLRQYPQALISPLMLQVTTADGTPHRLVAEDIVQMSDQALGDLARTCLRPGAINLQWYTADQGGYPYWHCELYPRDANADTLHRHLLWTLYLNDDFAQGETEFLFQQRKARPRTGSLLIAPTAFTHTHRGNRPVGGDKFIATSWILFQSAQALYGGE
>NZ_CP020985.1|WP_099803337.1|511814_512942_-|PA0069-family-radical-SAM-protein
MQKNSSPSASAAAERDVRSSRTVIKGRGTTAYVPGRFSVTTAVEIDDGWGALDADGETALRPKTVVAEEIARSIISRNNSPDIGFSQSVNPYRGCEHGCVYCFARPSHAYLDLSPGLDFETRIFAKPNAAALLRAEIARPSYQCSPIALGINTDAYQPAERRLHISRQCLEVLAQARHPVSFVTKAALIERDIDVLAEMAQHNLVSVYFSVTTLDNRLAAKMEPRAAAPHARLRAMQALHAAGVPVGVLVAPVIPMINDKELERILDAAAAHGARSAGYVLLRLPHELTQLWREWLELHYPDRAKHVMSLIQQMRGGKDYDSRFGKRMVGEGPFAELIAQRFSIAYRRLGFGRLPKLDTTQFRPPRPDTPQLDLF
>NZ_CP020985.1|WP_042676190.1|511325_511691_+|DUF1330-domain-containing-protein
MVAFSPNALSAFLDNQDTSAIVMLNLIRFQADGGRERYHRYLRLATPILARFDAHIVFSGDGLPVLTAGQAQAWDAVTLVQYPGRSAFKQMIADAEYQHAFEVGRSAIAEIVLQPFHGITL
>NZ_CP020985.1|WP_099803336.1|510551_511277_+|YafY-family-transcriptional-regulator
MSRTTRLFELLGLLRAHRRPVSAAALASELGVSQRSLYRDIDTLRALGAPLEGQAGVGYYLKPGFFLPSLAFSQEELDAVMLGLDWVKQRADPALARCGESALAKILSARKHGDGTGIDVAPPAILTAASTSKAVDHPQTAVLRDAIRRQCKLAIGYVDAQDTPSERIVWPIALVYFDDVRVLAAWCERRSAFRHFRVDRLQVRAVLEARYRQSRQALVKQWRQQDRDWRSLLTVSDTAQG
>NZ_CP020985.1|WP_099803339.1|521772_523569_+|M28-family-peptidase
MPRKILLCLAATLALAGCKREPADAPSAPAAQTPTESAPSAPVSRHTFSPDMTTGDFAELVKTLASDDFEGRGPGTPGEEKTVTYIRDQMQRIGLQPGNGDSWFQEVPMVETTADASTAPSLRSGEQTRTLAFGTDIVVGTRTGQAEVKLDNSELVFVGYGVDAPEQQWNDYAGQEWKGKTVVMFVNDPGFHTDDAKLFDGKRMTYYGRWTYKFEEAARKGAAAALIVHDTPGASYGWDVVKNSWSGPQYDLPAKDDPDPRLPVQGWISAETARQLFANASLDLAQAYKDASKRGFKPVPLKASWSVDLKSTIAAKTSRNVVGVLPGTSHADEAVLYMAHWDHLGKHPGESGDNIYNGAVDNATGVAGILEIADAFAHQDPKPARSVVFLAVTLEESGLLGSKYYVANPSFPLDKIAAVINLDAMSVAGRARDVTVVGMGSSELEDILKPIAAMQGRTLHAEATPQNGSYFRSDHFNFAKAGVPALYADGGEDLREGGTAAGRAAAEDYGRHRYHAPGDEYDAATWKLDGTIEDLEVVYGVGKEVAAGERWPNWYPGNPFKAARDRMMAGRPGTSAAAAQPADAASTATQTNTAKPRR
>NZ_CP020985.1|WP_099803340.1|523879_524323_-|PepSY-domain-containing-protein
MTQRLMKTALIGVLALVSQGALAQAADKPAKALTSGEVTSMLTAKGYTKVHDVKFEHGVWTADARSGDGKDVDVHIDPVTGRVYGDQTTSKLSEADVRASLSTGGYADVHDLKFTDGLWKADAKRNGQKVELHVDPEDGHVVSVDND
>NZ_CP020985.1|WP_099803341.1|524617_525751_-|glycoside-hydrolase-family-5-protein
MSAVCFSLRTLLRSTLLFIVFGSLPLAHAQTRALTYAGVNLSGAEYASSKKPGVLNKDYMYAAASDYTYFAGVGMNTIRLPILWERLQPTAGGELDPAQLALLQQAVARAKAAGMYLVIDIHNYAKYYGYKIGSPEVPVATFTDLWRRLALVFNSDNAVMFGVMNEPNNISASEWAGAAQAAIDAIRRTGANNLILVPGALWTGAHSWYSTTNDGYSNATALTSIYDPLDRYAFEVHQYLDADSSGTSSTCVSSTIGAERLRNFTQWLRTNRKRGFLAEFGTANNAVCNQALQGMLSHMETNADVWLGWTWWAAGSWWNLSYAYSVHPNKDGTDKPQMAILSPQAALATRAPVAAAAARTSAASTSATSVSVARTTR
>NZ_CP020985.1|WP_099803342.1|526388_527441_-|glycoside-hydrolase-family-5-protein
MKSLTTHTRRLRCRALSFLLLVTMPLAQAQSATGLKYAGVNLSGAEIKSSQKPGVLNIDYRYPAADEYAYFAGKHMNTVRLPILWERLQPRAGGELDPAQLALIRQAVANAKAAKMYVIVDVHNYAKYYGHTIGSTKVPISTFNDLWRRLAIAFKSDNAVIFGLMNEPYDIDPQAWATAAQASIDTIRKTGATNLILVPGALWTGAHSWYSTVAGQSNAVAMASIRDPLNRYAIEAHQYLDADSSGTSGGCVSATVGVERLRSFTEWLRLNKKRGFLAEFGTGNTVTCNLALNGMLGYMESNSDVWMGWSWWAAGAWWSGAYPFNVQPDAQGRDKPQMSILSPRARRITD
>NZ_CP020985.1|WP_099803343.1|528217_529291_-|glycoside-hydrolase-family-5-protein
MFRTPPHLSRLRTAALALTLIAAIPLIQAKEPAGPKKESAGLKYVGVNLSGAEFNSRKKPGTLFKDYTYPAASDFSYFAGKGMNTIRLPFLWERVQPELNGQLDQAQLGLIKKSLEAAKANKQYLILDLHNYATYSGKRIGTSDVPASALADLWRRLALEFKDDKAVIFGLMNEPNGISAPDWANAAQGTINAIRKTGAKNLILVPGTAYTGAHSWRSTSYGVSNAKALEILKDPGNNLAFEAHQYLDKDYSGTKPVCTSDSVGQEKLQGFTSWLRENKQKGFLGEFATANNPVCDKALEGMLTYMEKNSDVWLGWTWWAAGSWWKPDYPFTVQPGKDGSDKPQMAILSKYARRAGK
>NZ_CP020985.1|WP_022557795.1|529599_530658_+|NAD(P)-dependent-alcohol-dehydrogenase
MSTAHAYAAQAADQPLAPFVFERRAPGPNDVQIDIAYCGVCHSDLHTARNEWHNTLYPSVPGHEIVGRVTAVGNAVTGFKVGDLAGVGCMVDSCRSCASCQEGEEQYCEAGFTGTYNGPMFGGGENTYGGYSDHIVVDQKYVLRITHSDNLAAVAPLLCAGITTYSPLAHWKVGPGQKVGVVGLGGLGHMAVKIAKAMGATVVLFTTSESKRADALRLGASEVVISKDEAQMAAQYNTLDFILNTVAAPHNLDPFLNALKRDGAMVLVGVPEQSHPSPAVFNLIMKRRTLAGSLIGGIRQTQEMLDFCAKHNIVSDIETIRADQINAAYERMLKSDVKYRFVIDMATLDKAA
>NZ_CP020985.1|WP_099803344.1|530972_531251_-|hypothetical-protein
MISHAEEVEAIFGYWPEFADAKILLLTYERPDSVRLDISYIDADQQKSAIVGLRFTGVEDLDLADLRTENVLDILRILPACQCVLNWKRATA
>NZ_CP020985.1|WP_089140640.1|531326_531752_-|DUF4279-domain-containing-protein
MTEEEMPSCRHKLSLRLRHPSARLDSCTKQFGMEPLRQWSFGEPRTSNREVPLPGVWQNSYWTAQLDSIEDESLEQTLERILCRLEEHVTYLDRHRQSGGSVEVYIGFFLEGCNAGFCLTPELLSRSSKLGIAFSVDVYAP
>NZ_CP020985.1|WP_099803345.1|531765_533247_-|FAD-dependent-oxidoreductase
MSRKQAFQFLDLPRTMPTRIPVELRTSGDWGELYGRFDKADAQYQAGRCLDCGNPYCSWKCPVHNAIPQWLQLVQENRIEEAAALCHSTNPLPEVCGRVCPQDRLCEGSCTLEEFGAVTIGAVEKYIVDTAFKMGWRPDLGNVQPSGHRVAVIGAGPAGLACADRLARAGIEAVVYDRYEQIGGLLQFGIPSFKLDKSVIGKRREILEGMGVQFRLGVEIGKDISIEQLLAEYDAVFLGTGAYRYTDGGLPGQDLKNVLPALPFLVQNSRIVSGNDPHGRPIAGWEDQLALPDLTGKRVVVLGGGDTGMDCVRSAIRLGAAKVTCAYRRDEASMPGSAREVANAREEGVRFLFNRQPLSIESGADDEAIGVTVVETKLGEPDASGRRNAVPVEGSESLLEADVVIIAFGFSPTLPDWLSSQGVEAGSNGRIVAPADGNGRLPYQTTNPRLFAGGDCVRGADLVVTAVAEGRDAAGSIVQMLGVKAQVKEPAAA
>NZ_CP020985.1|WP_099803346.1|533368_537841_-|glutamate-synthase-large-subunit
MAPRTRQGLNDDGLYNSVRDERDACGFGMVAQLDDQPSRALVDTAIAALSRMTHRGGVAADGLTGDGCGLLIRKPDAFLRGLARDAGIALGTRYAAGVVFLPLDEADAARCRAELEAQLHSAGVHLRGWRVVPTDDSVCGQLARDTLPRIEQVFVDAGAEQTEDGFTLALFLARRRAEQALHAVENFYVTTLSPNGISYKGMVLPDKLSTFYPDLQRSDLSSSAIVFHQRFSTNTLPRWPLAHPFRLLAHNGEINTIEGNRRWAQARSKVWQTPRFDIAQFDPVISMHGSDSQSLDNMLELLIAGGMDLLQALRILVPPATQSLEFKDADLAAFYEFYGLNTEPWDGPAGIVACDSRYAACMLDRNGLRPARWMLTSDRHFLVASEAGVWELPAERITRKGKLGPGEMMAIDLKRGDLLDSDAIDRINRARAPYKQWLQQGVTYLQTELIDPSLVEEPFSEQTLRSYHKLFQLSTEEVEQVLRPLAETEQEATGSMGDDTPMAVLSRQTRPLYDYFRQAFAQVTNPPIDPLREGIAMSLTTQLGKETNIFHAGAETVNHVILNSPVLSQRKLRQLLKMEQYVERNRLIDLSYSLEEGLKAGLERICQEVEAAARAGAVMLLLSDRYPVPDRPMAHALLATGAVHHHLCKVGLRCDVNLIIETGTARDPHHMACLLGVGATAVYPYLAYQTLFDLGRRGILQLSKGGEQSQIGRRYRKGIYKGLSKIISKMGICTIASYRGAQLFEIVGLDPDVVDLCFADTPARIGGVDLARLDTEARELTVRAWNDQLKPEVGGLLKYVHGGEYHMYNPDVVMTLQRATRTGDAGDWQKYVDAVHARPASTLRDLVQLKRADTPTPLDDVAPAEDVLRRFDSAAISLGALSPEAHEALAIAMNRLGGRSNSGEGGEDPARYGTEKRSKIKQVASGRFGVTPEYLVNAEVLQIKVAQGAKPGEGGQLPGHKVNELIARLRYAKPGIGLISPPPHHDIYSIEDLAQLIYDLKQVNPTALVSVKLVAHAGVGTIAAGVVKAGADLITVSGHDGGTGASPVSSIRYAGVPWELGVAESHQALVANDLRERTILQTDGGLKTGLDVVKAALLGADSFGFGTAPMIVLGCKYLRICHLNNCATGVATQDERLRAGYFTGLPERVEHFFRLLAEEVRQWLSYLGVRSLDEIVGRTDLLEQLDVSPRPGVKVDLSRLLTHAQYDGNHCAAQRLYESPDSLATQMDGLLADAIANKRGGDHRFLIHNTDRSIGARLSGAIARAHGNHGMSDAPLNLRFRGTAGQSFGAFNAGGLQLELEGEANDYVGKGMAGGRLVVRPPRGARFEARNTPIVGNTCLYGATGGELFAAGRAGERFAVRNSGALAVVEGAGDHCCEYMTDGVVLVLGKVGLNFGAGFTGGLAYVLDIERDFVDRYNHELIDIHRVSAEGFENHRQHLHTLISRHRELTGSIWAQQILDEFRDYIGKFWLVKPKAASIESLTESLRRAA

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Crispr_ID: NZ_CP020985_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020985_2

2674504-2674590

Orphan

Consensus_repeat	Method
TCAGCGCCGGCAACGACGTCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020985_2

>merge|NZ_CP020985|2|2674504-2674590|CRISPRCasFinder
TCAGCGCCGGCAACGACGTCAACCTGGTCGCCGCAAAGCTCGATGCAGGCAAGGGCTTGGGGATCAGCGCCGGCAACGACATCAACG

>NZ_CP020985|2|2|2674504-2674590|CRISPRCasFinder
TCAGCGCCGGCAACGACGTCAAC	CTGGTCGCCGCAAAGCTCGATGCAGGCAAGGGCTTGGGGA
TCAGCGCCGGCAACGACATCAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020985.1\|WP_133125292.1\|2686266_2686653_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP020985.1\|WP_133125299.1\|2651077_2651398_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP020985.1\|WP_026007260.1\|2648353_2648638_-\|DUF4190-domain-containing-protein	unknown	unknown	gnl\|CDD\|379388
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379732
NZ_CP020985.1\|WP_145958633.1\|2679898_2680333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|223861
NZ_CP020985.1\|WP_133125293.1\|2685682_2686090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804057.1\|2687682_2687871_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP020985.1\|WP_154582576.1\|2688956_2689124_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274868
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	unknown	unknown	gnl\|CDD\|370150
NZ_CP020985.1\|WP_099804049.1\|2649218_2650751_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448

Protein	Function_ID	Function_description	E-value
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.15108e-52
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	5.11435e-45
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	gnl\|CDD\|379732	pfam15586, Imm8, Immunity protein 8. A predicted immunity protein with an alpha+beta fold and a conserved WEa (a: aromatic) motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Ntox7 family.	4.02525e-32
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	2.43778e-93
NZ_CP020985.1\|WP_026007260.1\|2648353_2648638_-\|DUF4190-domain-containing-protein	gnl\|CDD\|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	4.67005e-11
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	gnl\|CDD\|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	0.000184472
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	4.36974e-134
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	gnl\|CDD\|370150	pfam08845, SymE_toxin, Toxin SymE, type I toxin-antitoxin system. SymE (SOS-induced yjiW gene with similarity to MazE ) is an SOS-induced toxin. It inhibits cell growth, decreases protein synthesis and increases RNA degradation. It may play a role in the recycling of RNAs damaged under SOS response-inducing conditions. It is predicted to have an AbrB fold, similar to that of the antitoxin MazE. Its translation is repressed by the antisense RNA SymR, which acts as an antitoxin.	7.9862e-18
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	3.31941e-97
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.46544e-129
NZ_CP020985.1\|WP_099804049.1\|2649218_2650751_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0

>NZ_CP020985.1|WP_011345585.1|2670173_2671400_-|IS256-like-element-ISXax1-family-transposase
MSPRTHEVPDELLSSLLVNYTKPEDLIGENGLLKQLTKRLVERALDAEMTEHLGHDKHEPVANAAGNTRNGRSRKTLKGEFGELPIEIPRDRHGSFAPQLIPKHQTRWAGFDDKILSLYARGMTVREIQSHLEEMYGTEVSPSLISSVTDAVVEEVKAWQARPLDPVYPIVYLDCIHVKVREGAVRVKAVYLAIGITMGGEKEVLGLWLAQAEGAKFWLQVVTELRNRGVQDIFIACVDGLKGFPEAIEAVFPQTTVQLCIVHMVRHSLNYVSWKRRAEVAADLKRIYACATVEEAEQALTEFEAKWDAQYPPISQSWRRNWSRLIPFFDYPPEIRKVIYTTNAIESVNMSLRKLTKNRGAFPSDEALMKLFYLALRNITKKWTLPIRDWKAALNRFTIQFEGRLPQR
>NZ_CP020985.1|WP_099804052.1|2660921_2662622_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREEADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVTNADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRNEERGTRGNSLSYSLPWGWWTFALATSSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGSRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPAYGARVIYQF
>NZ_CP020985.1|WP_099804051.1|2658232_2660191_-|tetratricopeptide-repeat-protein
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGTDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPGYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDDWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGTAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQRERQLGLDLDFRWGGTP
>NZ_CP020985.1|WP_099804050.1|2656352_2658251_-|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRAFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQVDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQQPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP020985.1|WP_046832236.1|2655095_2656349_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP020985.1|WP_099801654.1|2654652_2655099_-|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVDADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR
>NZ_CP020985.1|WP_133125298.1|2652985_2653894_+|sel1-repeat-family-protein
MKSKYLAWGGSILLVAGLGVVIFWKFGMAEHPVESVSATKTHALPSDNSAGEFGAVQAGADQRAVRPVTNSNSSLEKFLDLKERANRGDPAAQRDLSEAYGRCVAVSGDPQKFLGTYEAIAKQATSQSNAKGMMNVARAYVEECAVVDGGAIVPLDARNLWLEQAARGGDLAAQARLQMSTLKPLHGEDLRGFVDKVAVAGDPAAVFELGQLLAGNSDISSLGEYGSVAAGPVSGYAWSIAACQMGLNCGAGSDLMNSICMNTGGCSSASFESYVRSNLLGVGDAALLDSKVKEVKNILSKN
>NZ_CP020985.1|WP_133125299.1|2651077_2651398_-|hypothetical-protein
MLDDDKAGKTSANKYRAEWYLTNQSVFTAGELLPDFKSKRLKGFLSEALVKDIRTQQSLTSRPSKKQIGLFLAEKFSSGAEKNPFDNETQSRFEKRLQALQDRFPT
>NZ_CP020985.1|WP_099804049.1|2649218_2650751_-|aldehyde-dehydrogenase-family-protein
MSADLLKALDLAASNSGTYLGEATWSQATGAGVLQPLNPTTNAVIAEVQATTPEDYELIVQRAQTAFKVWRTTPAPRRGEAVRLCGEALRAHKDALGSLVALEMGKSKPEGDGEVQEMIDIADFAVGQSRMLYGYTMHSERPGHRMYEQYQPLGLVGIISAFNFPVAVWAWNAFLAAICGDICIWKPSNKTPLTAIATMKICNAALKDAGFPDIFFLINDAGTALSEKLVEDTRVPLISFTGSTQIGRVVAEKVARRLGRCLLELGGNNAIILDETADLKLAIPGIVFGAVGTAGQRCTTTRRLIVHASIYDTVLATLVKAYKQLDSKIGDPTDPANLMGPLNSQGAVAQFLDSIAKAKAAGGTVEVGGTAIDRPGNFVLPAIVTGLQNSDAVVQHETFAPILYVMKYSTLDEAIELQNGVPQGLSSSIFTQNLKAAEKFLSAAGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKVYMRRQTNTINYSDSLPLAQGIRFDL
>NZ_CP020985.1|WP_026007260.1|2648353_2648638_-|DUF4190-domain-containing-protein
MNVVVRQTSAMAIVSLVAGILGWTLIPFLGSICAIITGHLARAEIRRNPQALDGDGLAIGGLIMGWLAVALWIVGIAFFLLFFGGMAWLAAANS
>NZ_CP020985.1|WP_145958633.1|2679898_2680333_+|hypothetical-protein
MSVAPVMSNDSGLVRSSVDQTNVQATAAGTGVTAGANETRTRVDPATIPVTNIVGGGQTSLTQIDLPIGGLYRLSSGTATDRTAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFIRHLAASSRCRSHQPCPMKWLGA
>NZ_CP020985.1|WP_099804054.1|2680720_2681083_+|hypothetical-protein
MKARLFGLHSDNWDLKSEQPDDPGCFSEELRAVIGPEDFEGGDNFFIEVCTPGWIKNRHYGPTWGRFMLIVENYDYDEIREFISEYVGRFEGAEWNEIAIKLSRVMSWEFEDYVRFDKRT
>NZ_CP020985.1|WP_133125293.1|2685682_2686090_+|hypothetical-protein
MKTNFLCEKGVVGPLRSGMQRAEVRRVLGGYNEFKKSPFSQNTTDEFLNSGLHVFYSPDELIKGVELFPDVGALFKGDDLFSFKLAGLIKFLDCHGIGYKFGDVGIKIVEVGIRVYSPDMNESCEASIDSVYIEL
>NZ_CP020985.1|WP_133125292.1|2686266_2686653_+|hypothetical-protein
MIFERLNFGIGPILKGMGRSNVREILGDFDEFSKNSFAKNTTDNFSKHRVHVFYSEYDIVEGVEFMSGANLSIGGIKVFDENLEDFLKKAGDNGLNFERDDLGAVLPDVEASLFCLDGFYIKSVYFEL
>NZ_CP020985.1|WP_099804056.1|2687034_2687385_-|type-I-toxin-antitoxin-system-SymE-family-toxin
MRQPPSRTTTRKRARRQPPRDAVWRIKESPLTPMLTPEEIEAANAADLVKQRRVVRCPRPPQQLTVGYGYYPASDQRVPTLRLRGRWLEQLGFVIGSKISIRMRDGELVVSLASRS
>NZ_CP020985.1|WP_099804057.1|2687682_2687871_+|hypothetical-protein
MSNQGVIAGTDVSVTAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGRRPPKFK
>NZ_CP020985.1|WP_057660070.1|2688030_2688531_+|tryptophan-rich-sensory-protein
MIRGRSKKPQWLGLLGWLMLCYSIAGLGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVAQLTLNGLWSWLFFAWHQGAWAFADIVALWLVLVATIGAFAKRQALAEWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP020985.1|WP_154582576.1|2688956_2689124_+|hypothetical-protein
MTGLGPVMSFACMGNASAIASLLCQPLLRAGAGVAGITTIITTATIRPVRSVVFA
>NZ_CP020985.1|WP_007963907.1|2689217_2691725_+|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP020985.1|WP_099804903.1|2691769_2692741_+|homoserine-kinase
MQAQAQGSDRASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHSALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG

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Crispr_ID: NZ_CP020985_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020985_3

2674717-2674805

Orphan

Consensus_repeat	Method
TCAGCGCCGGCAACGACGTCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020985_3

>merge|NZ_CP020985|3|2674717-2674805|CRISPRCasFinder
TGCAGGCGGGCAACGACATCACCCTCACCGCCGCATCGGCCGCCACCAAGGAAGGCGGCATCACCCTGGCCGCCGGCAACGACGTCAAC

>NZ_CP020985|3|3|2674717-2674805|CRISPRCasFinder
TGCAGGCGGGCAACGACATCACC	CTCACCGCCGCATCGGCCGCCACCAAGGAAGGCGGCATCACCC
TGGCCGCCGGCAACGACGTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020985.1\|WP_133125292.1\|2686266_2686653_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP020985.1\|WP_133125299.1\|2651077_2651398_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP020985.1\|WP_026007260.1\|2648353_2648638_-\|DUF4190-domain-containing-protein	unknown	unknown	gnl\|CDD\|379388
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379732
NZ_CP020985.1\|WP_145958633.1\|2679898_2680333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|223861
NZ_CP020985.1\|WP_133125293.1\|2685682_2686090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804057.1\|2687682_2687871_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP020985.1\|WP_154582576.1\|2688956_2689124_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274868
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	unknown	unknown	gnl\|CDD\|370150
NZ_CP020985.1\|WP_099804049.1\|2649218_2650751_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448

Protein	Function_ID	Function_description	E-value
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.15108e-52
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	5.11435e-45
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	gnl\|CDD\|379732	pfam15586, Imm8, Immunity protein 8. A predicted immunity protein with an alpha+beta fold and a conserved WEa (a: aromatic) motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Ntox7 family.	4.02525e-32
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	2.43778e-93
NZ_CP020985.1\|WP_026007260.1\|2648353_2648638_-\|DUF4190-domain-containing-protein	gnl\|CDD\|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	4.67005e-11
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	gnl\|CDD\|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	0.000184472
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	4.36974e-134
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	gnl\|CDD\|370150	pfam08845, SymE_toxin, Toxin SymE, type I toxin-antitoxin system. SymE (SOS-induced yjiW gene with similarity to MazE ) is an SOS-induced toxin. It inhibits cell growth, decreases protein synthesis and increases RNA degradation. It may play a role in the recycling of RNAs damaged under SOS response-inducing conditions. It is predicted to have an AbrB fold, similar to that of the antitoxin MazE. Its translation is repressed by the antisense RNA SymR, which acts as an antitoxin.	7.9862e-18
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	3.31941e-97
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.46544e-129
NZ_CP020985.1\|WP_099804049.1\|2649218_2650751_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0

>NZ_CP020985.1|WP_011345585.1|2670173_2671400_-|IS256-like-element-ISXax1-family-transposase
MSPRTHEVPDELLSSLLVNYTKPEDLIGENGLLKQLTKRLVERALDAEMTEHLGHDKHEPVANAAGNTRNGRSRKTLKGEFGELPIEIPRDRHGSFAPQLIPKHQTRWAGFDDKILSLYARGMTVREIQSHLEEMYGTEVSPSLISSVTDAVVEEVKAWQARPLDPVYPIVYLDCIHVKVREGAVRVKAVYLAIGITMGGEKEVLGLWLAQAEGAKFWLQVVTELRNRGVQDIFIACVDGLKGFPEAIEAVFPQTTVQLCIVHMVRHSLNYVSWKRRAEVAADLKRIYACATVEEAEQALTEFEAKWDAQYPPISQSWRRNWSRLIPFFDYPPEIRKVIYTTNAIESVNMSLRKLTKNRGAFPSDEALMKLFYLALRNITKKWTLPIRDWKAALNRFTIQFEGRLPQR
>NZ_CP020985.1|WP_099804052.1|2660921_2662622_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREEADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVTNADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRNEERGTRGNSLSYSLPWGWWTFALATSSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGSRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPAYGARVIYQF
>NZ_CP020985.1|WP_099804051.1|2658232_2660191_-|tetratricopeptide-repeat-protein
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGTDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPGYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDDWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGTAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQRERQLGLDLDFRWGGTP
>NZ_CP020985.1|WP_099804050.1|2656352_2658251_-|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRAFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQVDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQQPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP020985.1|WP_046832236.1|2655095_2656349_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP020985.1|WP_099801654.1|2654652_2655099_-|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVDADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR
>NZ_CP020985.1|WP_133125298.1|2652985_2653894_+|sel1-repeat-family-protein
MKSKYLAWGGSILLVAGLGVVIFWKFGMAEHPVESVSATKTHALPSDNSAGEFGAVQAGADQRAVRPVTNSNSSLEKFLDLKERANRGDPAAQRDLSEAYGRCVAVSGDPQKFLGTYEAIAKQATSQSNAKGMMNVARAYVEECAVVDGGAIVPLDARNLWLEQAARGGDLAAQARLQMSTLKPLHGEDLRGFVDKVAVAGDPAAVFELGQLLAGNSDISSLGEYGSVAAGPVSGYAWSIAACQMGLNCGAGSDLMNSICMNTGGCSSASFESYVRSNLLGVGDAALLDSKVKEVKNILSKN
>NZ_CP020985.1|WP_133125299.1|2651077_2651398_-|hypothetical-protein
MLDDDKAGKTSANKYRAEWYLTNQSVFTAGELLPDFKSKRLKGFLSEALVKDIRTQQSLTSRPSKKQIGLFLAEKFSSGAEKNPFDNETQSRFEKRLQALQDRFPT
>NZ_CP020985.1|WP_099804049.1|2649218_2650751_-|aldehyde-dehydrogenase-family-protein
MSADLLKALDLAASNSGTYLGEATWSQATGAGVLQPLNPTTNAVIAEVQATTPEDYELIVQRAQTAFKVWRTTPAPRRGEAVRLCGEALRAHKDALGSLVALEMGKSKPEGDGEVQEMIDIADFAVGQSRMLYGYTMHSERPGHRMYEQYQPLGLVGIISAFNFPVAVWAWNAFLAAICGDICIWKPSNKTPLTAIATMKICNAALKDAGFPDIFFLINDAGTALSEKLVEDTRVPLISFTGSTQIGRVVAEKVARRLGRCLLELGGNNAIILDETADLKLAIPGIVFGAVGTAGQRCTTTRRLIVHASIYDTVLATLVKAYKQLDSKIGDPTDPANLMGPLNSQGAVAQFLDSIAKAKAAGGTVEVGGTAIDRPGNFVLPAIVTGLQNSDAVVQHETFAPILYVMKYSTLDEAIELQNGVPQGLSSSIFTQNLKAAEKFLSAAGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKVYMRRQTNTINYSDSLPLAQGIRFDL
>NZ_CP020985.1|WP_026007260.1|2648353_2648638_-|DUF4190-domain-containing-protein
MNVVVRQTSAMAIVSLVAGILGWTLIPFLGSICAIITGHLARAEIRRNPQALDGDGLAIGGLIMGWLAVALWIVGIAFFLLFFGGMAWLAAANS
>NZ_CP020985.1|WP_145958633.1|2679898_2680333_+|hypothetical-protein
MSVAPVMSNDSGLVRSSVDQTNVQATAAGTGVTAGANETRTRVDPATIPVTNIVGGGQTSLTQIDLPIGGLYRLSSGTATDRTAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFIRHLAASSRCRSHQPCPMKWLGA
>NZ_CP020985.1|WP_099804054.1|2680720_2681083_+|hypothetical-protein
MKARLFGLHSDNWDLKSEQPDDPGCFSEELRAVIGPEDFEGGDNFFIEVCTPGWIKNRHYGPTWGRFMLIVENYDYDEIREFISEYVGRFEGAEWNEIAIKLSRVMSWEFEDYVRFDKRT
>NZ_CP020985.1|WP_133125293.1|2685682_2686090_+|hypothetical-protein
MKTNFLCEKGVVGPLRSGMQRAEVRRVLGGYNEFKKSPFSQNTTDEFLNSGLHVFYSPDELIKGVELFPDVGALFKGDDLFSFKLAGLIKFLDCHGIGYKFGDVGIKIVEVGIRVYSPDMNESCEASIDSVYIEL
>NZ_CP020985.1|WP_133125292.1|2686266_2686653_+|hypothetical-protein
MIFERLNFGIGPILKGMGRSNVREILGDFDEFSKNSFAKNTTDNFSKHRVHVFYSEYDIVEGVEFMSGANLSIGGIKVFDENLEDFLKKAGDNGLNFERDDLGAVLPDVEASLFCLDGFYIKSVYFEL
>NZ_CP020985.1|WP_099804056.1|2687034_2687385_-|type-I-toxin-antitoxin-system-SymE-family-toxin
MRQPPSRTTTRKRARRQPPRDAVWRIKESPLTPMLTPEEIEAANAADLVKQRRVVRCPRPPQQLTVGYGYYPASDQRVPTLRLRGRWLEQLGFVIGSKISIRMRDGELVVSLASRS
>NZ_CP020985.1|WP_099804057.1|2687682_2687871_+|hypothetical-protein
MSNQGVIAGTDVSVTAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGRRPPKFK
>NZ_CP020985.1|WP_057660070.1|2688030_2688531_+|tryptophan-rich-sensory-protein
MIRGRSKKPQWLGLLGWLMLCYSIAGLGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVAQLTLNGLWSWLFFAWHQGAWAFADIVALWLVLVATIGAFAKRQALAEWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP020985.1|WP_154582576.1|2688956_2689124_+|hypothetical-protein
MTGLGPVMSFACMGNASAIASLLCQPLLRAGAGVAGITTIITTATIRPVRSVVFA
>NZ_CP020985.1|WP_007963907.1|2689217_2691725_+|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP020985.1|WP_099804903.1|2691769_2692741_+|homoserine-kinase
MQAQAQGSDRASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHSALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG

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Crispr_ID: NZ_CP020985_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020985_4

2682163-2682249

Orphan

Consensus_repeat	Method
TCAGCGCCGGCAACGACGTCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020985_4

>merge|NZ_CP020985|4|2682163-2682249|CRISPRCasFinder
TCAGCGCCGGCAACGACGTCAACCTGGTCGCCGCAAAGCTCGATGCAGGCAAGGGCTTGGGGATCAGCGCCGGCAACGACATCAACG

>NZ_CP020985|4|4|2682163-2682249|CRISPRCasFinder
TCAGCGCCGGCAACGACGTCAAC	CTGGTCGCCGCAAAGCTCGATGCAGGCAAGGGCTTGGGGA
TCAGCGCCGGCAACGACATCAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020985.1\|WP_133125292.1\|2686266_2686653_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_158526630.1\|2671472_2679008_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP020985.1\|WP_099804058.1\|2692815_2693130_-\|EthD-family-reductase	unknown	unknown	gnl\|CDD\|131173
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379732
NZ_CP020985.1\|WP_089096571.1\|2693291_2694596_+\|threonine-synthase	unknown	unknown	gnl\|CDD\|236418
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP020985.1\|WP_154582576.1\|2688956_2689124_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_133125293.1\|2685682_2686090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_145958633.1\|2679898_2680333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|223861
NZ_CP020985.1\|WP_099804057.1\|2687682_2687871_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274868
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	unknown	unknown	gnl\|CDD\|370150

Protein	Function_ID	Function_description	E-value
NZ_CP020985.1\|WP_089096571.1\|2693291_2694596_+\|threonine-synthase	gnl\|CDD\|236418	PRK09225, PRK09225, threonine synthase; Validated.	0
NZ_CP020985.1\|WP_158526630.1\|2671472_2679008_+\|hypothetical-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	8.31941e-26
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	5.11435e-45
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP020985.1\|WP_099804058.1\|2692815_2693130_-\|EthD-family-reductase	gnl\|CDD\|131173	TIGR02118, TIGR02118, conserved hypothetical protein. This model represents a small family of proteins of unknown function, each about 105 amino acids in length. Conserved sites in the multiple alignment include a pair of aromatic residues, a histidine, and an aspartate. [Hypothetical proteins, Conserved].	8.01395e-35
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	gnl\|CDD\|379732	pfam15586, Imm8, Immunity protein 8. A predicted immunity protein with an alpha+beta fold and a conserved WEa (a: aromatic) motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Ntox7 family.	4.02525e-32
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	2.43778e-93
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.15108e-52
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	gnl\|CDD\|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	0.000184472
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	4.36974e-134
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.46544e-129
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	3.31941e-97
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	gnl\|CDD\|370150	pfam08845, SymE_toxin, Toxin SymE, type I toxin-antitoxin system. SymE (SOS-induced yjiW gene with similarity to MazE ) is an SOS-induced toxin. It inhibits cell growth, decreases protein synthesis and increases RNA degradation. It may play a role in the recycling of RNAs damaged under SOS response-inducing conditions. It is predicted to have an AbrB fold, similar to that of the antitoxin MazE. Its translation is repressed by the antisense RNA SymR, which acts as an antitoxin.	7.9862e-18

>NZ_CP020985.1|WP_099804054.1|2680720_2681083_+|hypothetical-protein
MKARLFGLHSDNWDLKSEQPDDPGCFSEELRAVIGPEDFEGGDNFFIEVCTPGWIKNRHYGPTWGRFMLIVENYDYDEIREFISEYVGRFEGAEWNEIAIKLSRVMSWEFEDYVRFDKRT
>NZ_CP020985.1|WP_145958633.1|2679898_2680333_+|hypothetical-protein
MSVAPVMSNDSGLVRSSVDQTNVQATAAGTGVTAGANETRTRVDPATIPVTNIVGGGQTSLTQIDLPIGGLYRLSSGTATDRTAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFIRHLAASSRCRSHQPCPMKWLGA
>NZ_CP020985.1|WP_158526630.1|2671472_2679008_+|hypothetical-protein
MLIDTVGFDGGGSILAQNLLDLTLRSDYTHRAGADLVSNGNFNLRLGGNLVNESTLKAARTLDITASSITNRAGANILSNDTRLNGGNVIDNAGSVSGNGALLLVANSVYNTGSIVGGNVSVNTGTLVNGADLGGATDNAAYASALLGSTGNMNLIVRDQLLNRDARIFSLGNIAIGGAQDGGGTLVSRTGGVNNLSGSIEADGSILIAANQLNNRRRVVNTTSVSTDPGNDDVYSGGELIEGKAIRNIQGARAPYPYKGLAPGIYRNYQVIQQEQLSSASAEGRIAAGGNILLSGSVTNNASTIAAAGVFAANQRGLGGLSDGMIVGGEQLLNQALALNQTVRQSDVEHIVTAITNDCMQPVGQKVVCYYEEEDQRLSSSTVSSSYIALGASMTGNQGVSINGANISNGAVGSDGRSISGASLNGVGAQGGLNGRTTQSAVGVGGQAVVGRANGSAGSIRVATGTSGSAGTQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTHVQTTAAGTGVTAGTNGTRTRVDPATIPVTNIVVGGQTSLTQIDLPIGGLYRLSSGTATDRTAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQKVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGNNLVSEAAKAINGVGILSGITASNTLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDVVSVSTGKDLIVAAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGKVASRTSISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVETSNTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASAATKEGGITLAAGNDVNLLADSEQHDAVQDMTKKKKGTFSSKTTTTHDEWQDTLAVGTALSGESVNISAGNDVAVVGSTLLATGDVRLAAGNDITIESAQDTSSEAHSFSQRRSGLTGGIGGGVASIGYSHARSNSQNGTDSVTQVASSVGSTDGNLVVSAGNQLTIAASDIGAGKDLTLAAKDIALLARQDTVDNEASQSSKSNGFSIGVTYDPAASYRSARDSTTKNMVNTGSTMSKISRDAEGAAAGTMAAITPVVVQASSHRSNASQNESTSDARVSQLAAGGNLTLLASDGSITSHGTQMSAEGNALLLASKDIVFDVAHNTQSSGNASTGKGWGFNNAAGLPYGNYNQQGTGNGQTDTITGTQLSVGGNASLTTTQGDIALTASNIAAQGNVSLRAAGDLTIQSGQDILGNANQSTSKGIGTVVISDTERFAGYNKKTHTDDNAQVTQVASNVGSLGGSVSLTAGGAYTQSASNVVAAKDVDIIAASIQLLTANQSSSASQQDDDLKIGAFARIKSPLIDLINNVDDARKSDGRLGAMQGMAAAANAYQTAKAVQSGSLLSVEAGVGFATNESSFDSSSQISQGSTITGGGNVSLKTTEGDLHIVQGNLKAGNTLTLDSARDLVLEAGNSSNTEQSKGSNAGFEVGVGASVGAQTGVYAYVQASVGSHKSNVDGSTWQNTQLAGQNIALTSEGDTTLRGAVAKGDRIDVQTGGDLTIESLQDKLDIQSKESSVGARVQVSFGTAWDASGYASGAKANGDYLGVVEQSGLFAGNGGYHVTAGNVNLIGGAIASTNAGASELTADSLTFTDLKNQMDYSASSGSISGGFGSTGNQTDANGNPIERTAGEQSRDIGNNIANGNYGTANTGSFMPGMPMSESGSDTSYTRATLTEGNIKIGGKTTTAAALGINTDESAAHEAVATLPDVRKILGEQQAMAAAIGTVVQTGVSIRNDINASIDEAQRQKKEAKAALEDPALSASLTSEQKIQLAMVAVEADKEIERLQKVGVLVSSITGGLSAASGSTGQIVAGTLAPVASYQIGQYFKENATRNTVDGGNRGEEGSASHLLAHSVLGAAIASAGGGSELIGAITAAGAEASAPALAKFLYGRDSNDLNAEEKSTISAVVGLGGAVLGSFTDDLRGAIVGSSIAKNAVDNNWGEVGHYSTMATVLYLAGFSERDAKAIALASWSPDTDTRNAITIKNIEAGNTAKGDQQNIHLLDGESDQLKVVAKQKELGAQVAEILSEINNLRDSPEGKAAILSNPDNQRILHAFGDSFAHVQKDGTHYSGVVGHLSDGVDPDDPAKHPQAYANYVSSLYQIAIEGKGIVKQAGNLDELSAAVSSKNTEAAQKAVLAAAAELRGGKDPELINSPLSDCKLYKECSENKANSIINGMYGVWPVGPPLINWSNLPK
>NZ_CP020985.1|WP_011345585.1|2670173_2671400_-|IS256-like-element-ISXax1-family-transposase
MSPRTHEVPDELLSSLLVNYTKPEDLIGENGLLKQLTKRLVERALDAEMTEHLGHDKHEPVANAAGNTRNGRSRKTLKGEFGELPIEIPRDRHGSFAPQLIPKHQTRWAGFDDKILSLYARGMTVREIQSHLEEMYGTEVSPSLISSVTDAVVEEVKAWQARPLDPVYPIVYLDCIHVKVREGAVRVKAVYLAIGITMGGEKEVLGLWLAQAEGAKFWLQVVTELRNRGVQDIFIACVDGLKGFPEAIEAVFPQTTVQLCIVHMVRHSLNYVSWKRRAEVAADLKRIYACATVEEAEQALTEFEAKWDAQYPPISQSWRRNWSRLIPFFDYPPEIRKVIYTTNAIESVNMSLRKLTKNRGAFPSDEALMKLFYLALRNITKKWTLPIRDWKAALNRFTIQFEGRLPQR
>NZ_CP020985.1|WP_099804052.1|2660921_2662622_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREEADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVTNADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRNEERGTRGNSLSYSLPWGWWTFALATSSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGSRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPAYGARVIYQF
>NZ_CP020985.1|WP_099804051.1|2658232_2660191_-|tetratricopeptide-repeat-protein
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGTDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPGYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDDWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGTAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQRERQLGLDLDFRWGGTP
>NZ_CP020985.1|WP_099804050.1|2656352_2658251_-|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRAFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQVDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQQPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP020985.1|WP_046832236.1|2655095_2656349_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP020985.1|WP_099801654.1|2654652_2655099_-|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVDADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR
>NZ_CP020985.1|WP_133125298.1|2652985_2653894_+|sel1-repeat-family-protein
MKSKYLAWGGSILLVAGLGVVIFWKFGMAEHPVESVSATKTHALPSDNSAGEFGAVQAGADQRAVRPVTNSNSSLEKFLDLKERANRGDPAAQRDLSEAYGRCVAVSGDPQKFLGTYEAIAKQATSQSNAKGMMNVARAYVEECAVVDGGAIVPLDARNLWLEQAARGGDLAAQARLQMSTLKPLHGEDLRGFVDKVAVAGDPAAVFELGQLLAGNSDISSLGEYGSVAAGPVSGYAWSIAACQMGLNCGAGSDLMNSICMNTGGCSSASFESYVRSNLLGVGDAALLDSKVKEVKNILSKN
>NZ_CP020985.1|WP_133125293.1|2685682_2686090_+|hypothetical-protein
MKTNFLCEKGVVGPLRSGMQRAEVRRVLGGYNEFKKSPFSQNTTDEFLNSGLHVFYSPDELIKGVELFPDVGALFKGDDLFSFKLAGLIKFLDCHGIGYKFGDVGIKIVEVGIRVYSPDMNESCEASIDSVYIEL
>NZ_CP020985.1|WP_133125292.1|2686266_2686653_+|hypothetical-protein
MIFERLNFGIGPILKGMGRSNVREILGDFDEFSKNSFAKNTTDNFSKHRVHVFYSEYDIVEGVEFMSGANLSIGGIKVFDENLEDFLKKAGDNGLNFERDDLGAVLPDVEASLFCLDGFYIKSVYFEL
>NZ_CP020985.1|WP_099804056.1|2687034_2687385_-|type-I-toxin-antitoxin-system-SymE-family-toxin
MRQPPSRTTTRKRARRQPPRDAVWRIKESPLTPMLTPEEIEAANAADLVKQRRVVRCPRPPQQLTVGYGYYPASDQRVPTLRLRGRWLEQLGFVIGSKISIRMRDGELVVSLASRS
>NZ_CP020985.1|WP_099804057.1|2687682_2687871_+|hypothetical-protein
MSNQGVIAGTDVSVTAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGRRPPKFK
>NZ_CP020985.1|WP_057660070.1|2688030_2688531_+|tryptophan-rich-sensory-protein
MIRGRSKKPQWLGLLGWLMLCYSIAGLGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVAQLTLNGLWSWLFFAWHQGAWAFADIVALWLVLVATIGAFAKRQALAEWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP020985.1|WP_154582576.1|2688956_2689124_+|hypothetical-protein
MTGLGPVMSFACMGNASAIASLLCQPLLRAGAGVAGITTIITTATIRPVRSVVFA
>NZ_CP020985.1|WP_007963907.1|2689217_2691725_+|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP020985.1|WP_099804903.1|2691769_2692741_+|homoserine-kinase
MQAQAQGSDRASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHSALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG
>NZ_CP020985.1|WP_099804058.1|2692815_2693130_-|EthD-family-reductase
MIKVSVMYPYRDGARFDHAYYRDQHMPLVSARMGAACLKYTVDKGISGGEAGSPPAFIGMCHIFCESVETFDAGFGPHAQEILADIANYTDLTPVMQISEVVVD
>NZ_CP020985.1|WP_089096571.1|2693291_2694596_+|threonine-synthase
MFISTRGGAPAASLSQAIAAGLAPDGGLYVPQTLPPARTLVAGAGLADTATALLQPFFEGDALAAELPAICAEAFDFPAPLVALGTPGDYALELFHGPTAAFKDFGARFLAACLTRLRRAEDRPLTILVATSGDTGAAVAAAFHRQPGLRVVVLYPDGRVSPRQAHQLGCFGDNIQALRVAGSFDDCQAMVKQALNDAALQTQVPLSSANSISLGRLLPQMSYYAHAALEHHAASGSVLNLVVPTGNLGNALAAIIARALGVPLGRIALASNANHVLPDYFAGDAYVPQPSVATLANAMDVGAPSNFERLRWLYNGDDAALREEFRALSVDDAAIRHTVQQRFARYGEVHCPHTATAVHVLEQLRAEGAEGGTGDWAVAATAHPAKFEGVVEPLIGRAVEVPPALAALLQRPAQAEALAPDYAALRQRLLADAA

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Crispr_ID: NZ_CP020985_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020985_5

2682376-2682464

Orphan

Consensus_repeat	Method
TCAGCGCCGGCAACGACGTCAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020985_5

>merge|NZ_CP020985|5|2682376-2682464|CRISPRCasFinder
TGCAGGCGGGCAACGACATCACCCTCACCGCCGCATCGGCCGCCACCAAGGAAGGCGGCATCACCCTGGCCGCCGGCAACGACGTCAAC

>NZ_CP020985|5|5|2682376-2682464|CRISPRCasFinder
TGCAGGCGGGCAACGACATCACC	CTCACCGCCGCATCGGCCGCCACCAAGGAAGGCGGCATCACCC
TGGCCGCCGGCAACGACGTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020985.1\|WP_133125292.1\|2686266_2686653_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_158526630.1\|2671472_2679008_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379124
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	unknown	unknown	gnl\|CDD\|181856
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP020985.1\|WP_099804058.1\|2692815_2693130_-\|EthD-family-reductase	unknown	unknown	gnl\|CDD\|131173
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379732
NZ_CP020985.1\|WP_089096571.1\|2693291_2694596_+\|threonine-synthase	unknown	unknown	gnl\|CDD\|236418
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP020985.1\|WP_154582576.1\|2688956_2689124_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_133125293.1\|2685682_2686090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_145958633.1\|2679898_2680333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	unknown	unknown	gnl\|CDD\|188455
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|223861
NZ_CP020985.1\|WP_099804057.1\|2687682_2687871_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274868
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	unknown	unknown	gnl\|CDD\|370150

Protein	Function_ID	Function_description	E-value
NZ_CP020985.1\|WP_089096571.1\|2693291_2694596_+\|threonine-synthase	gnl\|CDD\|236418	PRK09225, PRK09225, threonine synthase; Validated.	0
NZ_CP020985.1\|WP_158526630.1\|2671472_2679008_+\|hypothetical-protein	gnl\|CDD\|379124	pfam13332, Fil_haemagg_2, Haemagluttinin repeat.	8.31941e-26
NZ_CP020985.1\|WP_057660070.1\|2688030_2688531_+\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	5.11435e-45
NZ_CP020985.1\|WP_046832236.1\|2655095_2656349_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP020985.1\|WP_099804058.1\|2692815_2693130_-\|EthD-family-reductase	gnl\|CDD\|131173	TIGR02118, TIGR02118, conserved hypothetical protein. This model represents a small family of proteins of unknown function, each about 105 amino acids in length. Conserved sites in the multiple alignment include a pair of aromatic residues, a histidine, and an aspartate. [Hypothetical proteins, Conserved].	8.01395e-35
NZ_CP020985.1\|WP_099804054.1\|2680720_2681083_+\|hypothetical-protein	gnl\|CDD\|379732	pfam15586, Imm8, Immunity protein 8. A predicted immunity protein with an alpha+beta fold and a conserved WEa (a: aromatic) motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Ntox7 family.	4.02525e-32
NZ_CP020985.1\|WP_099804903.1\|2691769_2692741_+\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	2.43778e-93
NZ_CP020985.1\|WP_007963907.1\|2689217_2691725_+\|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I	gnl\|CDD\|181856	PRK09436, thrA, bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional.	0
NZ_CP020985.1\|WP_099801654.1\|2654652_2655099_-\|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD	gnl\|CDD\|188455	TIGR03940, PGA_PgaD, poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD. Members of this protein family are PgaD, essential to the production of poly-beta-1,6-N-acetyl-D-glucosamine (PGA). This cytoplasmic membrane protein appears to be an auxiliary subunit to the PGA synthase, PgaC (TIGR03937). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.15108e-52
NZ_CP020985.1\|WP_099804050.1\|2656352_2658251_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP020985.1\|WP_133125298.1\|2652985_2653894_+\|sel1-repeat-family-protein	gnl\|CDD\|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	0.000184472
NZ_CP020985.1\|WP_099804052.1\|2660921_2662622_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	4.36974e-134
NZ_CP020985.1\|WP_011345585.1\|2670173_2671400_-\|IS256-like-element-ISXax1-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.46544e-129
NZ_CP020985.1\|WP_099804051.1\|2658232_2660191_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	3.31941e-97
NZ_CP020985.1\|WP_099804056.1\|2687034_2687385_-\|type-I-toxin-antitoxin-system-SymE-family-toxin	gnl\|CDD\|370150	pfam08845, SymE_toxin, Toxin SymE, type I toxin-antitoxin system. SymE (SOS-induced yjiW gene with similarity to MazE ) is an SOS-induced toxin. It inhibits cell growth, decreases protein synthesis and increases RNA degradation. It may play a role in the recycling of RNAs damaged under SOS response-inducing conditions. It is predicted to have an AbrB fold, similar to that of the antitoxin MazE. Its translation is repressed by the antisense RNA SymR, which acts as an antitoxin.	7.9862e-18

>NZ_CP020985.1|WP_099804054.1|2680720_2681083_+|hypothetical-protein
MKARLFGLHSDNWDLKSEQPDDPGCFSEELRAVIGPEDFEGGDNFFIEVCTPGWIKNRHYGPTWGRFMLIVENYDYDEIREFISEYVGRFEGAEWNEIAIKLSRVMSWEFEDYVRFDKRT
>NZ_CP020985.1|WP_145958633.1|2679898_2680333_+|hypothetical-protein
MSVAPVMSNDSGLVRSSVDQTNVQATAAGTGVTAGANETRTRVDPATIPVTNIVGGGQTSLTQIDLPIGGLYRLSSGTATDRTAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFIRHLAASSRCRSHQPCPMKWLGA
>NZ_CP020985.1|WP_158526630.1|2671472_2679008_+|hypothetical-protein
MLIDTVGFDGGGSILAQNLLDLTLRSDYTHRAGADLVSNGNFNLRLGGNLVNESTLKAARTLDITASSITNRAGANILSNDTRLNGGNVIDNAGSVSGNGALLLVANSVYNTGSIVGGNVSVNTGTLVNGADLGGATDNAAYASALLGSTGNMNLIVRDQLLNRDARIFSLGNIAIGGAQDGGGTLVSRTGGVNNLSGSIEADGSILIAANQLNNRRRVVNTTSVSTDPGNDDVYSGGELIEGKAIRNIQGARAPYPYKGLAPGIYRNYQVIQQEQLSSASAEGRIAAGGNILLSGSVTNNASTIAAAGVFAANQRGLGGLSDGMIVGGEQLLNQALALNQTVRQSDVEHIVTAITNDCMQPVGQKVVCYYEEEDQRLSSSTVSSSYIALGASMTGNQGVSINGANISNGAVGSDGRSISGASLNGVGAQGGLNGRTTQSAVGVGGQAVVGRANGSAGSIRVATGTSGSAGTQVGANTQDATLATSGGIVKMSVAPVMSNDSGLVRSSVDQTHVQTTAAGTGVTAGTNGTRTRVDPATIPVTNIVVGGQTSLTQIDLPIGGLYRLSSGTATDRTAMGRAATGLGGINAWRSNGPGRRYLIETDPRFVNYDNFISSDFLLDKLGVDPEWTQTRLGDGFYEQRLVLDQITQLTGRRYLGNYADGVAQYRALLESGVAAAGQLQLSMGVGLTAAQAAALTQDIVWMVEQEYQGQKVLVPVVYLASNSLQLRGNGALIAGGNVELNASNAMNNQGVIAGADVSITAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGNNLVSEAAKAINGVGILSGITASNTLQLMAGNDMTLTGTRVQAGGSAALIAGNTLSLTPSALRDDNGLMRGGDVVSVSTGKDLIVAAGNDLQLHGVTIAAGGSAALQAGNNLSLTPTTGLDGKVASRTSISTGDSLQLTAGNDLTIRQADVKAGGDLIAAAGNNLNVASVLNDSQTNSDNSRNGKTRVTTTTTTQTIDQQALTAGGNLILSAGNDVNLVAAKLDAGKGLGISAGNDINASTLTTVETSNTLETRKRFKQTTSTSDETVHGTEFSAGGNLAMQAGNDITLTAASAATKEGGITLAAGNDVNLLADSEQHDAVQDMTKKKKGTFSSKTTTTHDEWQDTLAVGTALSGESVNISAGNDVAVVGSTLLATGDVRLAAGNDITIESAQDTSSEAHSFSQRRSGLTGGIGGGVASIGYSHARSNSQNGTDSVTQVASSVGSTDGNLVVSAGNQLTIAASDIGAGKDLTLAAKDIALLARQDTVDNEASQSSKSNGFSIGVTYDPAASYRSARDSTTKNMVNTGSTMSKISRDAEGAAAGTMAAITPVVVQASSHRSNASQNESTSDARVSQLAAGGNLTLLASDGSITSHGTQMSAEGNALLLASKDIVFDVAHNTQSSGNASTGKGWGFNNAAGLPYGNYNQQGTGNGQTDTITGTQLSVGGNASLTTTQGDIALTASNIAAQGNVSLRAAGDLTIQSGQDILGNANQSTSKGIGTVVISDTERFAGYNKKTHTDDNAQVTQVASNVGSLGGSVSLTAGGAYTQSASNVVAAKDVDIIAASIQLLTANQSSSASQQDDDLKIGAFARIKSPLIDLINNVDDARKSDGRLGAMQGMAAAANAYQTAKAVQSGSLLSVEAGVGFATNESSFDSSSQISQGSTITGGGNVSLKTTEGDLHIVQGNLKAGNTLTLDSARDLVLEAGNSSNTEQSKGSNAGFEVGVGASVGAQTGVYAYVQASVGSHKSNVDGSTWQNTQLAGQNIALTSEGDTTLRGAVAKGDRIDVQTGGDLTIESLQDKLDIQSKESSVGARVQVSFGTAWDASGYASGAKANGDYLGVVEQSGLFAGNGGYHVTAGNVNLIGGAIASTNAGASELTADSLTFTDLKNQMDYSASSGSISGGFGSTGNQTDANGNPIERTAGEQSRDIGNNIANGNYGTANTGSFMPGMPMSESGSDTSYTRATLTEGNIKIGGKTTTAAALGINTDESAAHEAVATLPDVRKILGEQQAMAAAIGTVVQTGVSIRNDINASIDEAQRQKKEAKAALEDPALSASLTSEQKIQLAMVAVEADKEIERLQKVGVLVSSITGGLSAASGSTGQIVAGTLAPVASYQIGQYFKENATRNTVDGGNRGEEGSASHLLAHSVLGAAIASAGGGSELIGAITAAGAEASAPALAKFLYGRDSNDLNAEEKSTISAVVGLGGAVLGSFTDDLRGAIVGSSIAKNAVDNNWGEVGHYSTMATVLYLAGFSERDAKAIALASWSPDTDTRNAITIKNIEAGNTAKGDQQNIHLLDGESDQLKVVAKQKELGAQVAEILSEINNLRDSPEGKAAILSNPDNQRILHAFGDSFAHVQKDGTHYSGVVGHLSDGVDPDDPAKHPQAYANYVSSLYQIAIEGKGIVKQAGNLDELSAAVSSKNTEAAQKAVLAAAAELRGGKDPELINSPLSDCKLYKECSENKANSIINGMYGVWPVGPPLINWSNLPK
>NZ_CP020985.1|WP_011345585.1|2670173_2671400_-|IS256-like-element-ISXax1-family-transposase
MSPRTHEVPDELLSSLLVNYTKPEDLIGENGLLKQLTKRLVERALDAEMTEHLGHDKHEPVANAAGNTRNGRSRKTLKGEFGELPIEIPRDRHGSFAPQLIPKHQTRWAGFDDKILSLYARGMTVREIQSHLEEMYGTEVSPSLISSVTDAVVEEVKAWQARPLDPVYPIVYLDCIHVKVREGAVRVKAVYLAIGITMGGEKEVLGLWLAQAEGAKFWLQVVTELRNRGVQDIFIACVDGLKGFPEAIEAVFPQTTVQLCIVHMVRHSLNYVSWKRRAEVAADLKRIYACATVEEAEQALTEFEAKWDAQYPPISQSWRRNWSRLIPFFDYPPEIRKVIYTTNAIESVNMSLRKLTKNRGAFPSDEALMKLFYLALRNITKKWTLPIRDWKAALNRFTIQFEGRLPQR
>NZ_CP020985.1|WP_099804052.1|2660921_2662622_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MWMRSAPLALAVCLCAIAGLAAAQQSAPTTLDRQEQLRQAEEIQRRQEQERQAPFAGPREEADRVDARSTVLPKEDLCFSITRVRLSGAGDDAARFAWLWTSLRRYQGRCIGRAGIDIIRRRALDQLVARGLVTTRIGVPEQDLSRGELRFELMPGRLREVRVVSETEGAHWKTALPLRTGDLLDLRAIEQAVEQFKRLPSQDAKIDIAPGEAPGESDLVITLQHGRRWRGVTNADDSGVEATGRVQGGLDVSLDNPLGLNDLLSIGYSHDLATRNEERGTRGNSLSYSLPWGWWTFALATSSYRYHQRVDGFLQTFQSSGESSNAQLDIQRVLHRDGTSKTSAGVVIGRRRARSYLDGVEIGIQRRDTSSAEFYLTHRRYLGTMQLDMRLAHRRGTPWFNSQWTGYDPQIGFPTFRYGVTTLDISTALPFKLGPVPMAWESSLRAQTAGELLLGSEFVTIGSRYSVRGFDGEATLGAEKGAYWRNTLSFPVQQIGLTPYLGLDAGRIDGTSASGLRGRSLVGGAVGLRGGWFGASVDAFAGWAIHRPDGFGSAQPAYGARVIYQF
>NZ_CP020985.1|WP_099804051.1|2658232_2660191_-|tetratricopeptide-repeat-protein
MQQAEQFRGRQRYTDALAIYERVLHADPRDRGAYTMRALTLSDLGSAQLAAEAMWRHPDWFSQQERERLDNDRVARMIGWASAEPVDAAHRYAETDQALANAARIQRDAPPQAAWEATRLRVDSLVALNQRQRHRDVIANYQALRAEGVDVPGYVLPTVGDSLMGLRRPAEAESVLRQALQHSPNDFNTQLLLGYALLEQERFDEAMPLFESLAATQAPWPRREGATSGYENWDRFSADIALATARSAANDNRGAEALLRERAAIGTDNAELQAALASIEARRGQTTQALQRNRMALTLDPHQKQARSGVVEAQRDLDRLDLADAAFASLQPGYPDDAGLQRLGASLERQRGWQVHLSHAWGRSENDTPTNSTSPLGNHFGSSLLEAESPLLGERWRVGLRARDDWADFQDTRVRYRSFWLGTHYRYDRLDFSAYGGRALDDFDRDGTAWALDAGWRFSDAWYGSVAWRTRDPEASLQARRLGITGDSIGAAVRWTPSDESRWELQARQLRYSDGNRRDQLDLSGSQRLWANPHVLVDGLFAASAGRAEDDRAVDYFNPRHSSAVAAGVRIEQIGWRRYDDAFRQRLEVTAGPTYQSGFGSRWVPALAYRHLWSLGDGSALSYGVSWSRPVYDGQRERQLGLDLDFRWGGTP
>NZ_CP020985.1|WP_099804050.1|2656352_2658251_-|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MGRYAVIRLPLLLVALLLMTFASSAQAGLLVLSYHDIRDDVAAKGDPDRYAVSTSNFAAHLDWLRSHAYHPVSVQQVLDARAGKRALPSRPVLLTFDDGLRSVYTRAFPLLQAYGYPALVAPVTSWVELPAGQVVPYGPRDFTRDDFVTWAQLREMQDSGLVEIGSHSDDLHKGIPGNPFGNETPAAVTRRWDAGNGYESEAHYRQRIETDLRHSRDAMVAHLGKPPRAMVWPYAAYNRASNEIAARLGMTLSFDLEGRSHEADIGQQGRDRVDGQSLASLGRLLLFNNPDVRDLAGELRRDLSRDGVRAIQVDLDYVYDPDPAQLERNLDVLVQRVKDIGPSHVFLQAFADPDGDGAADALYFPNRHLPMRADLFGRVAWQLRTRAGVRVFAWLPVLGFHLPDAQQQAALQIRGNDPKDVPRLDPGNPRTRQLVADIYEDLAANTYFEGLLFHDDAYLRDDEIPAYGNGDPAKRTQQLIGFTQELKAAAERWRPKLVTVRNLFAQPVLEPHSEAWFAQRLEAFASAYDYTALMAMPYMEQANDANAWLTQLATRVGQQPRGFDKTIFELQTVDWRSGKPLPDGVLLAHSKLLLAAGVRHLAYYPDDFIGGHPSLPEAREAISARQFPYLER
>NZ_CP020985.1|WP_046832236.1|2655095_2656349_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MTTSLLLAALFNFAFYYPIIMAFFWMIGGIYYHLRRERGTPGPSKPPPMASEPFVSILMPCYNEAKHVAETIAAMSAQQYADFEIIAINDGSTDRTAEVLDDLTHHHPRLRVVHLEQNHGKANALRVGTLAARSDYLVCVDADAILDPNATRWMVGHLIAGPRVGGVTGNPRVRNRTTLMGRMQVGEFSAIVGLIKRAQRVYGRLFTVSGVICAFRRSALHHVGFWSDNMVTEDIDISWRLQLDGWDIRYEPNALCWILMPETFRGLWMQRLRWARGGVEVLLSHGRRALEWRSRRMWAVLLEYALSLAWAYAMLLIIVLWLLGKFIALPPALYVDTILPRWHGLVLAVVCLLQFATSLMIERRYEKGLARQFFWVIWYPAAFWMIGMLTAVIAFPRALLARRNKRARWKSPDRGIQ
>NZ_CP020985.1|WP_099801654.1|2654652_2655099_-|poly-beta-1,6-N-acetyl-D-glucosamine-biosynthesis-protein-PgaD
MTPPIINLPQRLGRSRRLAYGAATAGAWMVYFYLWAPLATLIAWFFGLRSAYTELYLQHNALDPFALGSLPVIALMSAVTTVGWAEYNRLRFVDADKRKRPRTVAEPDVDQRLGATEQLGTLLRHSRISSVAMDKFARPVAVRVVRHR
>NZ_CP020985.1|WP_133125298.1|2652985_2653894_+|sel1-repeat-family-protein
MKSKYLAWGGSILLVAGLGVVIFWKFGMAEHPVESVSATKTHALPSDNSAGEFGAVQAGADQRAVRPVTNSNSSLEKFLDLKERANRGDPAAQRDLSEAYGRCVAVSGDPQKFLGTYEAIAKQATSQSNAKGMMNVARAYVEECAVVDGGAIVPLDARNLWLEQAARGGDLAAQARLQMSTLKPLHGEDLRGFVDKVAVAGDPAAVFELGQLLAGNSDISSLGEYGSVAAGPVSGYAWSIAACQMGLNCGAGSDLMNSICMNTGGCSSASFESYVRSNLLGVGDAALLDSKVKEVKNILSKN
>NZ_CP020985.1|WP_133125293.1|2685682_2686090_+|hypothetical-protein
MKTNFLCEKGVVGPLRSGMQRAEVRRVLGGYNEFKKSPFSQNTTDEFLNSGLHVFYSPDELIKGVELFPDVGALFKGDDLFSFKLAGLIKFLDCHGIGYKFGDVGIKIVEVGIRVYSPDMNESCEASIDSVYIEL
>NZ_CP020985.1|WP_133125292.1|2686266_2686653_+|hypothetical-protein
MIFERLNFGIGPILKGMGRSNVREILGDFDEFSKNSFAKNTTDNFSKHRVHVFYSEYDIVEGVEFMSGANLSIGGIKVFDENLEDFLKKAGDNGLNFERDDLGAVLPDVEASLFCLDGFYIKSVYFEL
>NZ_CP020985.1|WP_099804056.1|2687034_2687385_-|type-I-toxin-antitoxin-system-SymE-family-toxin
MRQPPSRTTTRKRARRQPPRDAVWRIKESPLTPMLTPEEIEAANAADLVKQRRVVRCPRPPQQLTVGYGYYPASDQRVPTLRLRGRWLEQLGFVIGSKISIRMRDGELVVSLASRS
>NZ_CP020985.1|WP_099804057.1|2687682_2687871_+|hypothetical-protein
MSNQGVIAGTDVSVTAGNLLNQGRISGTGSVALEARNDLLNQGQIQGRDVALVAGRRPPKFK
>NZ_CP020985.1|WP_057660070.1|2688030_2688531_+|tryptophan-rich-sensory-protein
MIRGRSKKPQWLGLLGWLMLCYSIAGLGAMASIQAASFYAQLQRPGWAPPGWLFGPVWTVLYGMMAVSVWLVWRRGGWAGARVALTLFVAQLTLNGLWSWLFFAWHQGAWAFADIVALWLVLVATIGAFAKRQALAEWLLVPYLAWVSFAAALNFSVWQLNPQVLG
>NZ_CP020985.1|WP_154582576.1|2688956_2689124_+|hypothetical-protein
MTGLGPVMSFACMGNASAIASLLCQPLLRAGAGVAGITTIITTATIRPVRSVVFA
>NZ_CP020985.1|WP_007963907.1|2689217_2691725_+|bifunctional-aspartate-kinase/homoserine-dehydrogenase-I
MSSPAVSFEPAAVLASSARTVVHKFGGTSVADAERYRHVAQLLLARDETVQVTVVSAMKGVTDALIELAELAAKNRPEWRERWHETRARHRGAAVALLGEHSGPTVEWLDERFEHLSQILGALAVIGELPREVLDRVQGLGEVYSAQLLGDHFRAIGEDCAVLDARDVLVVNRGELGVDVDWEASAQRLATWRQAHPQTRVVVTGFVARDRADRITTLGRNGSDYSGAIFAALFDADELHIWTDVDGVLSADPRVVPEAVQLETLSYDEACELAYFGAKVVHPQTMSPAIERGLPIIIRNTFQPEHPGTRITASSAVSGPIKGLTLSPDLAVLNLEGTGLIGVPGTAERVFAALRTAQVSVVMISQGSSEHSICCVVKQHESERARNALLQAFAHELTVGQVQRVQLTTGISVLAAVGDGMAGQPGVAARLFESLGRAQVNILAIAQGSSERNISVAIDAAHATKALRAAHAGFWLSPQTFSVGVIGPGNVGAALLDQLRVAQPQLLGKANLDLRLRAVVSRGRMLLDERGLVGDWRDAFASATTATDLERFTAHLLSAHLPHTVIIDCSGSAEVADRYAGWLAAGIHVVTPNKQAGSGPLARYEAICAAADASGARFRYEATVGAGLPVITTLRDLVDTGDAVTSIEGIFSGTLAWLFNKYDGSVPFAELVTQARGMGYTEPDPRDDLSGVDVARKLVILAREAGRSISLEDVQVESLVPEALRQASVDDFMARLPEVDAAFAQRLADARARGNVLRYVAQLPPDRAPSVGLVELPADHAFANLRLTDNVVQFTTRRYCENPLVVQGPGAGPEVTAAGVFADLLRVAAGEGARL
>NZ_CP020985.1|WP_099804903.1|2691769_2692741_+|homoserine-kinase
MQAQAQGSDRASPGKHGLHEARAFAPASVANVAVGFDLLGYPIDGVGDTVTVRRIEAPVVRIAAIRGTTVALPLDAERNTAGAALISLRAALQLPYGFEIEIDKGIALSSGMGGSAASCVAALVAANALLASPLDHHQLYQYALDGEAVASGSRHGDNLGPLFAGGLVLCTLERLVPINVPAAWHSLLVHPDAVLETRRAREALAGNYQLREFVAQSTNLALVLAGCHAGDADLVRAGLRDVLIEPRRAPLIAGFADAKQAALDHSALGASISGAGPSVFAWFESRAAAEAAAPAVQAGFAAVGFDSQAWVSPIASPAARLLG
>NZ_CP020985.1|WP_099804058.1|2692815_2693130_-|EthD-family-reductase
MIKVSVMYPYRDGARFDHAYYRDQHMPLVSARMGAACLKYTVDKGISGGEAGSPPAFIGMCHIFCESVETFDAGFGPHAQEILADIANYTDLTPVMQISEVVVD
>NZ_CP020985.1|WP_089096571.1|2693291_2694596_+|threonine-synthase
MFISTRGGAPAASLSQAIAAGLAPDGGLYVPQTLPPARTLVAGAGLADTATALLQPFFEGDALAAELPAICAEAFDFPAPLVALGTPGDYALELFHGPTAAFKDFGARFLAACLTRLRRAEDRPLTILVATSGDTGAAVAAAFHRQPGLRVVVLYPDGRVSPRQAHQLGCFGDNIQALRVAGSFDDCQAMVKQALNDAALQTQVPLSSANSISLGRLLPQMSYYAHAALEHHAASGSVLNLVVPTGNLGNALAAIIARALGVPLGRIALASNANHVLPDYFAGDAYVPQPSVATLANAMDVGAPSNFERLRWLYNGDDAALREEFRALSVDDAAIRHTVQQRFARYGEVHCPHTATAVHVLEQLRAEGAEGGTGDWAVAATAHPAKFEGVVEPLIGRAVEVPPALAALLQRPAQAEALAPDYAALRQRLLADAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	841356-841379	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	841102-841125	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	741221-741244	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	811287-811310	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	740336-740359	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	742914-742937	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	742903-742926	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	741208-741231	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	741227-741250	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	741205-741228	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	841425-841448	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	841424-841447	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	841409-841432	2	0.917
NZ_CP020985_1	1.2\|521153\|24\|NZ_CP020985\|CRISPRCasFinder	521153-521176	24	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	934481-934504	2	0.917
NZ_CP020985_1	1.1\|521099\|24\|NZ_CP020985\|CRISPRCasFinder	521099-521122	24	NZ_CP013739	Streptomyces globisporus C-1027 plasmid SGLP1, complete sequence	114529-114552	3	0.875
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NZ_CP054029	Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence	463188-463214	3	0.889
NZ_CP020985_1	1.2\|521153\|24\|NZ_CP020985\|CRISPRCasFinder	521153-521176	24	NC_015059	Granulicella tundricola MP5ACTX9 plasmid pACIX904, complete sequence	14492-14515	4	0.833
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1614849-1614875	4	0.852
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NZ_CP039905	Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence	51861-51887	5	0.815
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	367183-367209	5	0.815
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	AF440695	Virus PhiCh1, complete genome	58196-58222	5	0.815
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NC_004084	Natrialba phage PhiCh1, complete genome	58196-58222	5	0.815
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	657721-657747	5	0.815
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NZ_CP030128	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence	345670-345696	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP029362	Streptomyces globisporus strain TFH56 plasmid pTFSG1, complete sequence	61592-61618	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1778077-1778103	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_AP012556	Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence	22147-22173	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_016588	Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence	72444-72470	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	MH271303	Microbacterium phage MementoMori, complete genome	20739-20765	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	MN813682	Microbacterium phage Matzah, complete genome	21015-21041	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	MK937591	Microbacterium phage Cinna, complete genome	21039-21065	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP023152	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence	116472-116498	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP013739	Streptomyces globisporus C-1027 plasmid SGLP1, complete sequence	59488-59514	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	MT152150	Pseudomonas phage 8P, complete genome	40493-40519	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	1178659-1178685	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	399632-399658	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	1241207-1241233	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	1145574-1145600	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	836227-836253	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	1245812-1245838	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	149317-149343	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	303664-303690	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	66861-66887	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP049358	Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence	208557-208583	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP015095	Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence	75944-75970	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	321626-321652	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	375217-375243	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	646126-646152	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	434813-434839	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	558560-558586	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	616941-616967	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	507884-507910	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP019483	Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence	293668-293694	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP031159	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence	184933-184959	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	269636-269662	5	0.815
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	321288-321314	5	0.815
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NZ_CP026974	Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence	155076-155102	6	0.778
NZ_CP020985_1	1.3\|521207\|27\|NZ_CP020985\|CRISPRCasFinder	521207-521233	27	NZ_CP031159	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence	275912-275938	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP005961	Pseudomonas mandelii JR-1 plasmid unnamed, complete sequence	193825-193851	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	349994-350020	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1667668-1667694	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	436000-436026	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	182702-182728	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	473219-473245	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP009572	Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence	81085-81111	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	MT553342	Microbacterium phage Kelcole, complete genome	23692-23718	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NC_048068	Microbacterium phage OneinaGillian, complete genome	23339-23365	6	0.778
NZ_CP020985_1	1.4\|521264\|27\|NZ_CP020985\|CRISPRCasFinder	521264-521290	27	NZ_CP033874	Caulobacter sp. FWC26 plasmid p2	4960-4986	7	0.741

1. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

2. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

3. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

4. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

5. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

6. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

7. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

8. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

9. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

10. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

11. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

12. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

13. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.917

gagatcggtgccggtgcgcaaacc	CRISPR spacer
gagaccggtgccggcgcgcaaacc	Protospacer
****.*********.*********

14. spacer 1.2|521153|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 2, identity: 0.917

cgcatcggcgacaacgcgcgtacc	CRISPR spacer
cgcagcggcgacaacgcgcgcacc	Protospacer
**** ***************.***

15. spacer 1.1|521099|24|NZ_CP020985|CRISPRCasFinder matches to NZ_CP013739 (Streptomyces globisporus C-1027 plasmid SGLP1, complete sequence) position: , mismatch: 3, identity: 0.875

gagatcggtgccggtgcgcaaacc	CRISPR spacer
cagagcggtgccggtgcgcatacc	Protospacer
 *** *************** ***

16. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP054029 (Rhizobium sp. JKLM19E plasmid pPR19E02, complete sequence) position: , mismatch: 3, identity: 0.889

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
tcgctgggcctgaaggcgatcgtgtcc	Protospacer
 ********* *****.**********

17. spacer 1.2|521153|24|NZ_CP020985|CRISPRCasFinder matches to NC_015059 (Granulicella tundricola MP5ACTX9 plasmid pACIX904, complete sequence) position: , mismatch: 4, identity: 0.833

cgcatcggcgacaacgcgcgtacc	CRISPR spacer
cgcatcggcgacaacgcgcttctg	Protospacer
******************* * .

18. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ttcgtcgagcgcggcagccagatcatg	Protospacer
.***.********************

19. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP039905 (Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence) position: , mismatch: 5, identity: 0.815

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
ttggcgggccagaaggtgatcgtgtgc	Protospacer
 .* .******************** *

20. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
aaagcgggccagaaggtggtcgtgtcc	Protospacer
* . .*************.********

21. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to AF440695 (Virus PhiCh1, complete genome) position: , mismatch: 5, identity: 0.815

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
cagctggggcagacggtgatcgtgtcg	Protospacer
  ****** **** ************

22. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NC_004084 (Natrialba phage PhiCh1, complete genome) position: , mismatch: 5, identity: 0.815

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
cagctggggcagacggtgatcgtgtcg	Protospacer
  ****** **** ************

23. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 5, identity: 0.815

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
tggatgggccagaaattgatcgtgtcc	Protospacer
  * **********. ***********

24. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP030128 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.815

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
ttgcgcggccagaaggtgaccgtgtcc	Protospacer
 .**  *************.*******

25. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP029362 (Streptomyces globisporus strain TFH56 plasmid pTFSG1, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gtgaccgagcgcagcagccagatcagg	Protospacer
 * .********.*************

26. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
accggcgagcgcggcagccagatcgct	Protospacer
 .** *******************. *

27. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_AP012556 (Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gccgccgagcgcagcagcccgatcagc	Protospacer
 .**********.****** ******.

28. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_016588 (Azospirillum lipoferum 4B plasmid AZO_p6, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcggcgagcgcggcggccagatcctc	Protospacer
**** **********.********  .

29. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to MH271303 (Microbacterium phage MementoMori, complete genome) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgagcgcggcatcccgatcctc	Protospacer
**************** ** ****  .

30. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to MN813682 (Microbacterium phage Matzah, complete genome) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgagcgcggcatcccgatcctc	Protospacer
**************** ** ****  .

31. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to MK937591 (Microbacterium phage Cinna, complete genome) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgagcgcggcatcccgatcctc	Protospacer
**************** ** ****  .

32. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP023152 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gccgccgagcgcagcagcccgatcagc	Protospacer
 .**********.****** ******.

33. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP013739 (Streptomyces globisporus C-1027 plasmid SGLP1, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gtgaccgagcgcagcagccagatcagg	Protospacer
 * .********.*************

34. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to MT152150 (Pseudomonas phage 8P, complete genome) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gtccttgagcgcggcagccagatcagc	Protospacer
 ** ..********************.

35. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

36. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

37. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

38. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

39. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

40. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

41. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

42. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

43. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

44. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP049358 (Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
catgccgagcgcggcagtcaggtcagc	Protospacer
* .**************.***.****.

45. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP015095 (Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ttggccgagcgcggcaggcagagcagc	Protospacer
.* ************** **** ***.

46. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

47. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

48. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

49. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

50. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

51. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

52. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

53. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP019483 (Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

54. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP031159 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
catgccgagcgcggcagtcaggtcagc	Protospacer
* .**************.***.****.

55. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

56. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 5, identity: 0.815

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgggcgcggcagccggataaag	Protospacer
*******.***********.*** *.

57. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP026974 (Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
cagctgggccagaaagtgatcgtggaa	Protospacer
  ************.*********

58. spacer 1.3|521207|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP031159 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence) position: , mismatch: 6, identity: 0.778

acgctgggccagaaggtgatcgtgtcc	CRISPR spacer
acgctgggccagcaggtggtcgtcgtt	Protospacer
************ *****.****  ..

59. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP005961 (Pseudomonas mandelii JR-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
aagaccgggcgcggcagccagaccagt	Protospacer
   .***.**************.****

60. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gacgccgagcgcggcagccaggtgatg	Protospacer
  *******************.* *

61. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gacgccgagcgcggccgccagctcaac	Protospacer
  ************* ***** ***..

62. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
atcgccgagcgcggcagccaactgggc	Protospacer
 *******************. * .*.

63. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gtcgccgagcgcggcatcgagatcgcg	Protospacer
 *************** * *****.

64. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
atcgccgagcgcggcagccaactgggc	Protospacer
 *******************. * .*.

65. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP009572 (Sphingomonas taxi strain ATCC 55669 plasmid STP1, complete sequence) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
accgccgagcgcggcggccagttcaag	Protospacer
 .*************.***** ***.

66. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to MT553342 (Microbacterium phage Kelcole, complete genome) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgagcgcgtcagccagggcgag	Protospacer
************* *******. *..

67. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NC_048068 (Microbacterium phage OneinaGillian, complete genome) position: , mismatch: 6, identity: 0.778

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
ctcgccgagcgcgtcagccagggcgag	Protospacer
************* *******. *..

68. spacer 1.4|521264|27|NZ_CP020985|CRISPRCasFinder matches to NZ_CP033874 (Caulobacter sp. FWC26 plasmid p2) position: , mismatch: 7, identity: 0.741

ctcgccgagcgcggcagccagatcagt	CRISPR spacer
gcggccgagcgcgtcagccagatcgaa	Protospacer
 . ********** **********..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

145385 : 179237

Ralstonia_phage(20.0%)

transposase,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007967095.1\|145385_146720_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_099803230.1\|147300_148608_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_057661011.1\|148891_149440_-	hypothetical protein	NA	NA	NA	NA
WP_099803231.1\|149436_151404_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.0e-38	28.9
WP_099803232.1\|151553_152885_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_007972988.1\|153114_153429_-	hypothetical protein	NA	NA	NA	NA
WP_089111397.1\|153472_155992_-	serine/threonine protein kinase	A0A2P1EMR8	Moumouvirus	8.0e-12	29.2
WP_007967112.1\|155970_156510_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_089113450.1\|156859_157387_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_057661044.1\|157383_158454_+	DUF4880 domain-containing protein	NA	NA	NA	NA
WP_099803233.1\|158921_161807_+	TonB-dependent receptor	NA	NA	NA	NA
WP_089142765.1\|161910_163212_+	histidine-type phosphatase	NA	NA	NA	NA
WP_099803234.1\|163282_164587_+	endonuclease	NA	NA	NA	NA
WP_089142436.1\|165204_165948_-	hypothetical protein	NA	NA	NA	NA
WP_089111307.1\|167660_168747_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_099207515.1\|169891_170155_+	hypothetical protein	NA	NA	NA	NA
WP_123766583.1\|170364_170859_-	hypothetical protein	NA	NA	NA	NA
WP_017160267.1\|170992_171178_-	hypothetical protein	NA	NA	NA	NA
WP_011345585.1\|171442_172669_-\|transposase	IS256-like element ISXax1 family transposase	A0A218MNI5	uncultured_virus	2.2e-52	50.3
WP_099803235.1\|173041_175786_-	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	8.8e-81	29.2
WP_099803236.1\|175841_176882_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_099804800.1\|176845_178729_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_007964038.1\|178733_179237_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_2

452572 : 516348

Bacillus_phage(22.22%)

tRNA,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007968272.1\|452572_453124_+\|tail	phage tail protein	NA	NA	NA	NA
WP_007968270.1\|453192_453720_+\|tail	phage tail protein	A0A0U4JYA4	Arthrobacter_phage	1.0e-09	28.0
WP_099803320.1\|453780_454317_+\|tail	phage tail protein	NA	NA	NA	NA
WP_099803321.1\|454321_454879_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011257259.1\|454897_455185_-	hypothetical protein	NA	NA	NA	NA
WP_099803322.1\|455568_456363_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	4.9e-08	27.2
WP_003482308.1\|456362_457112_+	ABC transporter permease	NA	NA	NA	NA
WP_022560464.1\|457123_457669_+	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_003482305.1\|457665_458328_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_022560466.1\|458317_458608_+	STAS domain-containing protein	NA	NA	NA	NA
WP_089142541.1\|458618_459674_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_089142542.1\|459806_460187_-	hypothetical protein	NA	NA	NA	NA
WP_007968256.1\|460190_460736_-	glutathione peroxidase	Q70H87	Fowlpox_virus	2.0e-16	33.9
WP_099802889.1\|460889_461279_-	hypothetical protein	NA	NA	NA	NA
WP_099803323.1\|461497_463078_-	DNA recombination protein RmuC	NA	NA	NA	NA
WP_158525792.1\|463214_463361_-	hypothetical protein	NA	NA	NA	NA
WP_033481426.1\|463637_463868_+	hypothetical protein	NA	NA	NA	NA
WP_007968253.1\|464031_464652_+	glutathione S-transferase	NA	NA	NA	NA
WP_007968252.1\|464790_465171_+	hypothetical protein	NA	NA	NA	NA
WP_007971149.1\|465387_466803_+	amino acid permease	NA	NA	NA	NA
WP_099803324.1\|467033_469508_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_099803325.1\|470360_470750_-	DUF2628 domain-containing protein	NA	NA	NA	NA
WP_099803326.1\|470870_472619_-	diguanylate cyclase	A0A127AWB9	Bacillus_phage	5.3e-15	31.6
WP_089096453.1\|472710_473922_-	carbohydrate diacid regulon transcriptional regulator CdaR	NA	NA	NA	NA
WP_099803327.1\|474155_475325_-	glycerate kinase	W6LM47	Streptococcus_phage	1.2e-42	39.0
WP_099803328.1\|475350_476661_-	MFS transporter	NA	NA	NA	NA
WP_099803329.1\|477140_478397_-	peptidase M19	NA	NA	NA	NA
WP_022560498.1\|478683_479004_-	hypothetical protein	NA	NA	NA	NA
WP_007968235.1\|479122_480289_-	class I SAM-dependent rRNA methyltransferase	NA	NA	NA	NA
WP_039571260.1\|480553_481510_+	TerC family protein	K4F9T9	Cronobacter_phage	1.0e-31	30.6
WP_099803330.1\|481848_482634_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_099803331.1\|482753_483848_-	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
WP_099803332.1\|484087_486388_-	TonB-dependent receptor	NA	NA	NA	NA
WP_099206281.1\|486580_487438_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_099803333.1\|487599_488940_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_022560505.1\|490517_492242_-	membrane protein insertase YidC	NA	NA	NA	NA
WP_007968218.1\|492267_492705_-	ribonuclease P protein component	NA	NA	NA	NA
WP_002805908.1\|492743_492884_-	50S ribosomal protein L34	NA	NA	NA	NA
WP_007968215.1\|493126_494455_+	chromosomal replication initiator protein DnaA	NA	NA	NA	NA
WP_005912436.1\|494731_495832_+	DNA polymerase III subunit beta	A0A0A8IL17	Aurantimonas_phage	1.1e-53	37.1
WP_099803334.1\|496875_497982_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_089094340.1\|498096_500541_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.6e-113	34.7
WP_022557777.1\|500608_501445_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_005912440.1\|501629_502436_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_007968206.1\|502713_503907_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_005912443.1\|504060_504732_+	energy transducer TonB	NA	NA	NA	NA
WP_005912445.1\|504817_505579_+	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_005912447.1\|505625_506048_+	biopolymer transporter ExbD	NA	NA	NA	NA
WP_005912449.1\|506051_506465_+	biopolymer transporter ExbD	NA	NA	NA	NA
WP_007971889.1\|507011_507419_+	biopolymer transporter ExbD	NA	NA	NA	NA
WP_007968197.1\|507671_508439_-	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_005912451.1\|508446_508716_-	hypothetical protein	NA	NA	NA	NA
WP_099803335.1\|508790_510251_-	cardiolipin synthase	NA	NA	NA	NA
WP_099803336.1\|510551_511277_+	YafY family transcriptional regulator	NA	NA	NA	NA
WP_042676190.1\|511325_511691_+	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_099803337.1\|511814_512942_-	PA0069 family radical SAM protein	NA	NA	NA	NA
WP_007971900.1\|513128_513830_-	2OG-Fe(II) oxygenase	E3SK61	Synechococcus_phage	1.0e-17	47.2
WP_007968187.1\|514096_515437_-	outer membrane protein transport protein	NA	NA	NA	NA
WP_003482177.1\|515655_516348_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

DBSCAN-SWA_3

1676910 : 1745942

Stenotrophomonas_phage(47.22%)

holin,transposase,terminase,capsid,protease,head,tail,portal,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099803720.1\|1676910_1678992_+\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA
WP_099803721.1\|1679160_1681320_+	S46 family peptidase	NA	NA	NA	NA
WP_007968929.1\|1681413_1682058_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_099803722.1\|1682387_1683686_+	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_099803723.1\|1683753_1684836_+	SPOR domain-containing protein	NA	NA	NA	NA
WP_007968935.1\|1685049_1685796_+	CvpA family protein	NA	NA	NA	NA
WP_003483730.1\|1685826_1687293_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.1e-85	39.9
WP_099803724.1\|1687488_1688313_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_099803725.1\|1690278_1690698_+	hypothetical protein	NA	NA	NA	NA
WP_099803726.1\|1690886_1691630_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_007968943.1\|1692031_1692574_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_099803727.1\|1692554_1693691_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_007973706.1\|1693951_1695478_-	exopolyphosphatase	NA	NA	NA	NA
WP_003483747.1\|1695650_1697753_-	polyphosphate kinase 1	NA	NA	NA	NA
WP_099803728.1\|1697865_1699209_-	phosphate regulon sensor histidine kinase PhoR	W8CYF6	Bacillus_phage	6.5e-29	33.3
WP_003483753.1\|1699266_1699956_-	phosphate regulon transcriptional regulatory protein PhoB	W8CYM9	Bacillus_phage	1.0e-33	35.7
WP_033481216.1\|1700138_1701785_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_033481211.1\|1701934_1702243_+	glutaredoxin 3	A0A2L0UZG6	Agrobacterium_phage	2.7e-07	43.2
WP_007968963.1\|1702239_1702635_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_003483762.1\|1702861_1703869_+	isocitrate dehydrogenase	NA	NA	NA	NA
WP_005927840.1\|1704013_1704775_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_099803730.1\|1706000_1706651_+	hypothetical protein	NA	NA	NA	NA
WP_011345585.1\|1707065_1708292_-\|transposase	IS256-like element ISXax1 family transposase	A0A218MNI5	uncultured_virus	2.2e-52	50.3
WP_099803731.1\|1708334_1708604_-	DNA-binding protein	A0A2H4JE67	uncultured_Caudovirales_phage	4.1e-07	37.3
WP_099803732.1\|1708674_1709112_+	helix-turn-helix transcriptional regulator	E5E3P4	Burkholderia_phage	6.4e-10	32.9
WP_133125215.1\|1709341_1709818_-	hypothetical protein	NA	NA	NA	NA
WP_099803733.1\|1709905_1710892_-	phage late control D family protein	V9IQM7	Stenotrophomonas_phage	2.4e-89	52.6
WP_099803734.1\|1710888_1711290_-\|tail	phage tail protein	V9IQX3	Stenotrophomonas_phage	3.2e-40	62.9
WP_099803735.1\|1711302_1714173_-\|tail	phage tail tape measure protein	V9IQL1	Stenotrophomonas_phage	3.9e-204	48.7
WP_005922203.1\|1714202_1714316_-\|tail	GpE family phage tail protein	A0A0M4R2P3	Salmonella_phage	4.2e-06	68.6
WP_008572745.1\|1714324_1714627_-\|tail	phage tail assembly protein	V9IQM4	Stenotrophomonas_phage	2.2e-25	67.4
WP_099803736.1\|1714672_1715182_-\|tail	phage major tail tube protein	V9IQX1	Stenotrophomonas_phage	8.4e-70	76.3
WP_099803737.1\|1715211_1716378_-\|tail	phage tail sheath protein	E5FFG9	Burkholderia_phage	1.6e-132	62.1
WP_099803738.1\|1716389_1716749_-\|plate	baseplate assembly protein	V9IQW0	Stenotrophomonas_phage	1.6e-35	63.6
WP_099803739.1\|1716745_1717309_-\|plate	phage baseplate assembly protein V	Q9ZXL0	Pseudomonas_virus	4.8e-26	47.0
WP_099803740.1\|1717450_1718125_-	hypothetical protein	NA	NA	NA	NA
WP_099803741.1\|1718127_1718421_-	hypothetical protein	NA	NA	NA	NA
WP_099803742.1\|1718493_1720293_-	hypothetical protein	V9IQX0	Stenotrophomonas_phage	2.3e-85	39.0
WP_099803743.1\|1720305_1720851_-\|tail	phage tail protein I	V9IQK7	Stenotrophomonas_phage	4.9e-52	56.0
WP_133125214.1\|1722239_1722656_+	hypothetical protein	NA	NA	NA	NA
WP_099803744.1\|1722636_1723098_-	phage virion morphogenesis protein	V9IQH0	Stenotrophomonas_phage	6.1e-35	54.1
WP_099803745.1\|1723085_1723505_-\|tail	phage tail protein	A0A2H4J906	uncultured_Caudovirales_phage	9.7e-40	64.4
WP_099803746.1\|1723501_1723990_-	hypothetical protein	V9IQW8	Stenotrophomonas_phage	5.3e-29	53.6
WP_099803747.1\|1723989_1724631_-	glycoside hydrolase family 19 protein	V9IQK6	Stenotrophomonas_phage	5.1e-48	59.8
WP_005922189.1\|1724627_1724903_-\|holin	phage holin family protein	V9IQV8	Stenotrophomonas_phage	1.3e-21	59.8
WP_005929454.1\|1724895_1725252_-	membrane protein	V9IQG9	Stenotrophomonas_phage	3.5e-22	56.1
WP_039586330.1\|1725256_1725466_-\|tail	tail protein	K4PAW7	Burkholderia_phage	2.7e-14	58.0
WP_099803748.1\|1725465_1725933_-\|head	head completion/stabilization protein	V9IQW6	Stenotrophomonas_phage	1.8e-31	49.7
WP_099803749.1\|1726031_1726751_-\|terminase	terminase	Q9ZXM2	Pseudomonas_virus	3.8e-68	62.1
WP_099803750.1\|1726754_1727774_-\|capsid	phage major capsid protein, P2 family	Q9ZXM3	Pseudomonas_virus	3.5e-136	70.6
WP_099803751.1\|1727818_1728661_-\|capsid	GPO family capsid scaffolding protein	A0A2H4J928	uncultured_Caudovirales_phage	2.2e-67	53.3
WP_099803752.1\|1728782_1730567_+\|terminase	terminase ATPase subunit family protein	V9IQL5	Stenotrophomonas_phage	2.1e-272	76.7
WP_099803753.1\|1730566_1731580_+\|portal	phage portal protein	A0A2H4J922	uncultured_Caudovirales_phage	1.5e-139	71.9
WP_078560558.1\|1731605_1731851_+	Com family DNA-binding transcriptional regulator	V9IQK2	Stenotrophomonas_phage	2.8e-15	53.8
WP_089094893.1\|1731768_1732470_+	site-specific DNA-methyltransferase	V9IQV5	Stenotrophomonas_phage	3.8e-105	76.5
WP_089094894.1\|1732640_1733057_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_099803754.1\|1734310_1735460_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.3e-97	63.3
WP_099804865.1\|1739103_1740093_+	chemotaxis protein CheB	NA	NA	NA	NA
WP_131469915.1\|1740254_1740503_-	hypothetical protein	NA	NA	NA	NA
WP_099803755.1\|1740721_1741990_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_007968966.1\|1742518_1743811_+	trigger factor	NA	NA	NA	NA
WP_002806026.1\|1743903_1744530_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.0e-56	57.4
WP_003483788.1\|1744655_1745942_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.3e-137	59.9

DBSCAN-SWA_4

2251096 : 2313478

uncultured_Caudovirales_phage(40.0%)

integrase,transposase

attL 2246222:2246238|attR 2313586:2313602

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2246222:2246238	attL	NA	NA	NA	NA
WP_099803908.1\|2251096_2252431_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_158526629.1\|2252636_2252828_-	chromosome segregation protein ParM	NA	NA	NA	NA
WP_099803910.1\|2253515_2253908_-	hypothetical protein	NA	NA	NA	NA
WP_099803911.1\|2253950_2254262_-	hypothetical protein	NA	NA	NA	NA
WP_099803912.1\|2254433_2254730_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_099803913.1\|2254853_2255942_+	Fic family protein	NA	NA	NA	NA
WP_040145963.1\|2256420_2256825_+	hypothetical protein	NA	NA	NA	NA
WP_099804878.1\|2256785_2257550_+	hypothetical protein	NA	NA	NA	NA
WP_099804879.1\|2257630_2258326_-	hypothetical protein	NA	NA	NA	NA
WP_099803914.1\|2258875_2260486_+	MobA/MobL family protein	NA	NA	NA	NA
WP_145958629.1\|2260598_2260901_+	hypothetical protein	NA	NA	NA	NA
WP_145958630.1\|2260976_2261705_-	hypothetical protein	NA	NA	NA	NA
WP_108722827.1\|2261737_2262457_-	adenylate/guanylate cyclase domain-containing protein	NA	NA	NA	NA
WP_145958631.1\|2262459_2263017_-	hypothetical protein	NA	NA	NA	NA
WP_099803915.1\|2265151_2266675_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_099803916.1\|2266804_2267200_+	H-NS histone family protein	NA	NA	NA	NA
WP_133125311.1\|2267365_2267611_-	hypothetical protein	NA	NA	NA	NA
WP_133125310.1\|2267620_2268583_-	hypothetical protein	NA	NA	NA	NA
WP_099803917.1\|2268984_2269464_+	DNA repair protein RadC	NA	NA	NA	NA
WP_099803918.1\|2269661_2270300_+	hypothetical protein	NA	NA	NA	NA
WP_099804880.1\|2270401_2271052_+	hypothetical protein	NA	NA	NA	NA
WP_099804881.1\|2271226_2271460_+	hypothetical protein	NA	NA	NA	NA
WP_099803919.1\|2271552_2272620_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_099803920.1\|2272674_2273406_-	hypothetical protein	NA	NA	NA	NA
WP_099803921.1\|2273418_2275617_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_099803922.1\|2275620_2276919_-	ATP-binding protein	NA	NA	NA	NA
WP_099804882.1\|2276915_2278910_-	hypothetical protein	NA	NA	NA	NA
WP_108201665.1\|2280439_2282200_+	hypothetical protein	NA	NA	NA	NA
WP_099803925.1\|2282571_2283171_+	hypothetical protein	NA	NA	NA	NA
WP_133125308.1\|2283257_2284301_-	hypothetical protein	NA	NA	NA	NA
WP_099804883.1\|2284368_2285544_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_099803926.1\|2286247_2286685_+	hypothetical protein	NA	NA	NA	NA
WP_099803927.1\|2287893_2288394_+	hypothetical protein	NA	NA	NA	NA
WP_133125307.1\|2288508_2288985_+	hypothetical protein	NA	NA	NA	NA
WP_099803928.1\|2289552_2290443_+	MobA/MobL family protein	NA	NA	NA	NA
WP_099803929.1\|2290664_2291057_-	hypothetical protein	NA	NA	NA	NA
WP_011345585.1\|2291189_2292416_+\|transposase	IS256-like element ISXax1 family transposase	A0A218MNI5	uncultured_virus	2.2e-52	50.3
WP_099803930.1\|2292486_2293665_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_099803931.1\|2293661_2295884_+	peptidase domain-containing ABC transporter	F2Y2R6	Organic_Lake_phycodnavirus	8.8e-23	27.1
WP_099803932.1\|2295979_2296696_+	hypothetical protein	NA	NA	NA	NA
WP_133125306.1\|2296709_2297276_+	hypothetical protein	NA	NA	NA	NA
WP_099803933.1\|2297386_2298667_-	ABC transporter permease	NA	NA	NA	NA
WP_099803934.1\|2298729_2299161_-	toxin-activating lysine-acyltransferase	NA	NA	NA	NA
WP_099803935.1\|2299150_2300965_-	MchC protein	NA	NA	NA	NA
WP_099803936.1\|2301459_2303103_+	MobA/MobL family protein	NA	NA	NA	NA
WP_089111307.1\|2303305_2304392_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.9e-43	36.8
WP_099803937.1\|2304552_2305491_-	hypothetical protein	NA	NA	NA	NA
WP_158525787.1\|2305595_2307254_-	protein kinase family protein	NA	NA	NA	NA
WP_099803938.1\|2307250_2307997_-	hypothetical protein	NA	NA	NA	NA
WP_099803939.1\|2307999_2308833_-	VWA domain-containing protein	NA	NA	NA	NA
WP_108201666.1\|2308973_2309903_-	HEPN domain-containing protein	NA	NA	NA	NA
WP_158525786.1\|2310026_2311142_-	hypothetical protein	A0A2H4J138	uncultured_Caudovirales_phage	3.0e-96	55.5
WP_099804884.1\|2311141_2311765_-	hypothetical protein	A0A2H4J137	uncultured_Caudovirales_phage	1.4e-47	46.1
WP_099803940.1\|2311951_2313478_-\|integrase	site-specific integrase	NA	NA	NA	NA
2313586:2313602	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3023271 : 3090333

uncultured_Caudovirales_phage(28.57%)

integrase,transposase,plate

attL 3015616:3015632|attR 3088697:3088713

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3015616:3015632	attL	NA	NA	NA	NA
WP_039588095.1\|3023271_3025206_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A0U1UNT3	Pseudomonas_phage	7.0e-101	48.0
WP_082321416.1\|3025272_3025923_-	LysR family substrate-binding domain-containing protein	NA	NA	NA	NA
WP_039588094.1\|3026339_3027224_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_039588092.1\|3029274_3029994_-	hypothetical protein	NA	NA	NA	NA
WP_029996254.1\|3030199_3031078_+	M15 family metallopeptidase	A8ATW4	Listeria_phage	1.3e-06	36.5
WP_039588102.1\|3031188_3031449_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_029996252.1\|3031508_3032954_+	membrane protein	NA	NA	NA	NA
WP_039588091.1\|3032969_3036707_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_029996250.1\|3036703_3037687_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_039588090.1\|3037683_3038478_+	OmpA family protein	NA	NA	NA	NA
WP_039588089.1\|3038528_3039602_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_039588088.1\|3040415_3043235_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.1e-54	28.9
WP_029996245.1\|3043249_3044206_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_082321419.1\|3044959_3045529_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_039588087.1\|3045752_3046322_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_039588086.1\|3046318_3048724_+	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_002801620.1\|3050062_3050344_+	hypothetical protein	NA	NA	NA	NA
WP_029996241.1\|3050967_3052047_-	hypothetical protein	NA	NA	NA	NA
WP_082321415.1\|3052043_3053528_-	hypothetical protein	NA	NA	NA	NA
WP_082321418.1\|3053587_3056311_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_039588083.1\|3056417_3057206_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_029996236.1\|3057205_3058540_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_029996235.1\|3058692_3059301_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_033482858.1\|3059683_3060172_+	hypothetical protein	NA	NA	NA	NA
WP_029996233.1\|3060217_3060718_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_029996232.1\|3060721_3062218_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_003467612.1\|3062359_3062857_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_019302186.1\|3063004_3063493_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_029996231.1\|3063495_3065331_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_039588082.1\|3065294_3066386_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_039588081.1\|3066471_3069210_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.6e-90	29.6
WP_029996228.1\|3069241_3069595_+	hypothetical protein	NA	NA	NA	NA
WP_039588080.1\|3069687_3072450_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	8.4e-39	26.6
WP_046736019.1\|3072424_3073297_+	hypothetical protein	NA	NA	NA	NA
WP_039588079.1\|3073316_3076184_+	hypothetical protein	NA	NA	NA	NA
WP_039588078.1\|3076188_3077211_+	hypothetical protein	NA	NA	NA	NA
WP_039588076.1\|3077260_3077611_+	hypothetical protein	NA	NA	NA	NA
WP_029996221.1\|3079895_3080522_+	hypothetical protein	NA	NA	NA	NA
WP_033482571.1\|3080534_3081167_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_039588074.1\|3081252_3081630_+	DUF3742 family protein	NA	NA	NA	NA
WP_057417709.1\|3082453_3083452_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_039433051.1\|3083409_3084156_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_039588073.1\|3084391_3088660_+	AMP-binding protein	A0A2K9L3I8	Tupanvirus	9.9e-47	22.6
WP_099804143.1\|3088656_3089064_+	SDR family oxidoreductase	NA	NA	NA	NA
3088697:3088713	attR	NA	NA	NA	NA
WP_011345585.1\|3089106_3090333_+\|transposase	IS256-like element ISXax1 family transposase	A0A218MNI5	uncultured_virus	2.2e-52	50.3

DBSCAN-SWA_6

4795176 : 4803199

Escherichia_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099804653.1\|4795176_4796523_+	phosphomannomutase	A0A127AWJ1	Bacillus_phage	2.0e-33	27.1
WP_007962673.1\|4796569_4797973_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	4.2e-47	29.8
WP_089095960.1\|4798247_4799414_-	nucleotide sugar dehydrogenase	M1HZB2	Paramecium_bursaria_Chlorella_virus	7.2e-117	58.4
WP_099804654.1\|4799754_4800654_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.2e-26	35.8
WP_007971517.1\|4800650_4801208_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	3.9e-44	48.3
WP_007971516.1\|4801204_4802092_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.5e-93	57.4
WP_099804655.1\|4802143_4803199_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	3.2e-79	45.3

DBSCAN-SWA_7

4814311 : 4824420

Shigella_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099803754.1\|4814311_4815462_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.3e-97	63.3
WP_099804660.1\|4815522_4815657_-	glycosyltransferase	NA	NA	NA	NA
WP_099804661.1\|4815728_4816205_-	GtrA family protein	NA	NA	NA	NA
WP_099804662.1\|4816283_4817195_-	NAD-dependent epimerase/dehydratase family protein	E5ES47	Bathycoccus_sp._RCC1105_virus	5.3e-06	21.6
WP_089095950.1\|4817172_4818207_-	GDP-mannose 4,6-dehydratase	A0A1J0F996	Only_Syngen_Nebraska_virus	2.3e-106	56.6
WP_099804663.1\|4818203_4821914_-	glycosyltransferase	A0A218MKE2	uncultured_virus	1.7e-15	24.2
WP_099804664.1\|4821913_4823200_-	FkbM family methyltransferase	A0A1V0SAF0	Catovirus	1.8e-12	26.4
WP_089095947.1\|4823199_4824420_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-10	23.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020985

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection