CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP018649	Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1607 plasmid pSE81-1607-1, complete sequence	0 crisprs	NA	0	1
NZ_CP018650	Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1607 plasmid pSE81-1607-2, complete sequence	0 crisprs	cas14j	0	7
NZ_CP018648	Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1607 chromosome, complete genome	2 crisprs	DEDDh,DinG,WYL,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,PD-DExK	15	7

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4956 : 15420

Salmonella_phage(50.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001138014.1\|4956_7923_-\|transposase	Tn3-like element TnAs1 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	100.0
WP_001161490.1\|7926_8487_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	1.1e-59	100.0
WP_001323889.1\|8796_10374_+	PAS domain-containing protein	A0A1B0V854	Salmonella_phage	1.2e-95	99.4
WP_000027057.1\|10650_11511_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001235713.1\|11693_12251_-	recombinase family protein	Q1MVP4	Enterobacteria_phage	7.0e-94	100.0
WP_001143760.1\|12414_15420_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP018650

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 1063

Stx_converting_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015059604.1\|462_624_-	hypothetical protein	NA	NA	NA	NA
WP_000751876.1\|676_1063_-	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	3.0e-27	46.9

DBSCAN-SWA_2

10631 : 11189

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000725064.1\|10631_11189_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	5.8e-24	37.4

DBSCAN-SWA_3

28373 : 35281

Escherichia_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000925628.1\|28373_28796_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	2.0e-29	52.4
WP_000457542.1\|28795_30070_+	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	3.9e-156	64.5
WP_077681951.1\|30151_31129_-	ParB/RepB/Spo0J family partition protein	A0A1B0V750	Salmonella_phage	6.7e-84	53.5
WP_000427676.1\|31125_32331_-	ParA family protein	A0A077SL49	Escherichia_phage	1.5e-162	69.3
WP_000728919.1\|32745_33687_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	4.7e-74	54.7
WP_000176303.1\|33683_34289_-	DUF2913 family protein	NA	NA	NA	NA
WP_001527010.1\|34345_34681_-	hypothetical protein	NA	NA	NA	NA
WP_001541564.1\|34864_35281_-	hypothetical protein	O64348	Escherichia_phage	8.2e-07	42.9

DBSCAN-SWA_4

38829 : 39390

Ralstonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001240330.1\|38829_39390_+	recombinase family protein	A0A1W5LU24	Ralstonia_phage	1.5e-32	43.2

DBSCAN-SWA_5

44896 : 45061

Salmonella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001576629.1\|44896_45061_+	glycoside hydrolase family protein	A0A0M4R365	Salmonella_phage	3.3e-12	63.0

DBSCAN-SWA_6

50003 : 50836

Helicobacter_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000064919.1\|50003_50429_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.4e-24	50.4
WP_001541541.1\|50485_50836_+	helix-turn-helix domain-containing protein	A0A077SLN2	Escherichia_phage	1.9e-44	80.5

DBSCAN-SWA_7

53896 : 54679

Macacine_betaherpesvirus(100.0%)

integrase

attL 50171:50182|attR 56879:56890

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
50171:50182	attL	NA	NA	NA	NA
WP_000082169.1\|53896_54679_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.6e-51	91.1
WP_000082169.1\|53896_54679_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.6e-51	91.1
56879:56890	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP018648

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018648_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018648_1

1363826-1364403

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

9 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP018648_1

>merge|NZ_CP018648|1|1363826-1364403|CRISPRCasFinder,CRT,PILER-CR
GTGTTTATCCCCGCTGACGCGGGGAACACTATTTATAAGCGTGTCATCTATGCAACCCAACCGGTTTATCCCCGCTGGCGCGGGGAACACACCTGCCCGACCCAATAAGGAGGCCCTCGTGACGGTTTATCCCCGCTGGCGCGGGGAACACGGCCGCTGGTCAAATTCCCAATCTGAGCAATCCGGTTTATCCCCGCTGGCGCGGGGAACACATAGCCCCGGCAGCGATAGCTAAACCAGTTCCCGGTTTATCCCCGCTGGCGCGGGGAACACGCCTCAAAATCTCTCGGTGAGATGTAAGCGTCCGGTTTATCCCCGCTGGCGCGGGGAACACACCAGTGGTCAGCGGCGGATGAATTTGCCCTGCGGTTTATCCCCGCTGGCGCGGGGAACACGAGAATGCTCATGCGCGTGAGCGCCATATATTCGGTTTATCCCCGCTGGCGCGGGGAACACCATGGCAATTTTACGGCGGACGTGCTCGCTCTCGGTTTATCCCCGCTGGCGCGGGGAACACAGGCGGACCGAAAAACCGTTTTCAGCCAACGTCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP018648|1|1|1363826-1364403|CRISPRCasFinder
GTGTTTATCCCCGCTGACGCGGGGAACAC	TATTTATAAGCGTGTCATCTATGCAACCCAAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACCTGCCCGACCCAATAAGGAGGCCCTCGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCGCTGGTCAAATTCCCAATCTGAGCAATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATAGCCCCGGCAGCGATAGCTAAACCAGTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCTCAAAATCTCTCGGTGAGATGTAAGCGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACCAGTGGTCAGCGGCGGATGAATTTGCCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAATGCTCATGCGCGTGAGCGCCATATATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CATGGCAATTTTACGGCGGACGTGCTCGCTCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGCGGACCGAAAAACCGTTTTCAGCCAACGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP018648|1|1|1363826-1364403|CRT
GTGTTTATCCCCGCTGACGCGGGGAACAC	TATTTATAAGCGTGTCATCTATGCAACCCAAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACCTGCCCGACCCAATAAGGAGGCCCTCGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGCCGCTGGTCAAATTCCCAATCTGAGCAATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATAGCCCCGGCAGCGATAGCTAAACCAGTTCC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCCTCAAAATCTCTCGGTGAGATGTAAGCGTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACCAGTGGTCAGCGGCGGATGAATTTGCCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAATGCTCATGCGCGTGAGCGCCATATATT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CATGGCAATTTTACGGCGGACGTGCTCGCTCT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGGCGGACCGAAAAACCGTTTTCAGCCAACGT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP018648|1|1|1363828-1364403|PILER-CR
GTTTATCCCCGCTGACGCGGGGAACACTA	TTTATAAGCGTGTCATCTATGCAACCCAACCG
GTTTATCCCCGCTGGCGCGGGGAACACAC	CTGCCCGACCCAATAAGGAGGCCCTCGTGACG
GTTTATCCCCGCTGGCGCGGGGAACACGG	CCGCTGGTCAAATTCCCAATCTGAGCAATCCG
GTTTATCCCCGCTGGCGCGGGGAACACAT	AGCCCCGGCAGCGATAGCTAAACCAGTTCCCG
GTTTATCCCCGCTGGCGCGGGGAACACGC	CTCAAAATCTCTCGGTGAGATGTAAGCGTCCG
GTTTATCCCCGCTGGCGCGGGGAACACAC	CAGTGGTCAGCGGCGGATGAATTTGCCCTGCG
GTTTATCCCCGCTGGCGCGGGGAACACGA	GAATGCTCATGCGCGTGAGCGCCATATATTCG
GTTTATCCCCGCTGGCGCGGGGAACACCA	TGGCAATTTTACGGCGGACGTGCTCGCTCTCG
GTTTATCCCCGCTGGCGCGGGGAACACAG	GCGGACCGAAAAACCGTTTTCAGCCAACGTCG
GTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018648.1\|WP_000144830.1\|1364792_1365713_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP018648.1\|WP_001221538.1\|1355692_1356454_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP018648.1\|WP_000372384.1\|1361605_1362514_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP018648.1\|WP_000039870.1\|1374437_1375172_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP018648.1\|WP_000741653.1\|1357959_1358670_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP018648.1\|WP_001219253.1\|1357480_1357960_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP018648.1\|WP_000134246.1\|1356434_1357484_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP018648.1\|WP_000206417.1\|1367098_1368157_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP018648.1\|WP_000281483.1\|1365709_1366360_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP018648.1\|WP_001145541.1\|1373396_1374350_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP018648.1\|WP_001092251.1\|1360156_1361596_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP018648.1\|WP_000490481.1\|1362764_1363811_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP018648.1\|WP_000117945.1\|1368170_1368725_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP018648.1\|WP_000085107.1\|1366341_1367088_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP018648.1\|WP_000029737.1\|1370289_1372953_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP018648.1\|WP_000517480.1\|1358688_1359000_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP018648.1\|WP_001173663.1\|1359564_1360170_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP018648.1\|WP_001118109.1\|1359190_1359547_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP018648.1\|WP_000368579.1\|1368721_1370278_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP018648.1\|WP_001518648.1\|1364499_1364793_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930

Protein	Function_ID	Function_description	E-value
NZ_CP018648.1\|WP_000144830.1\|1364792_1365713_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.63116e-157
NZ_CP018648.1\|WP_001221538.1\|1355692_1356454_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
NZ_CP018648.1\|WP_000372384.1\|1361605_1362514_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP018648.1\|WP_000039870.1\|1374437_1375172_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.73232e-139
NZ_CP018648.1\|WP_000741653.1\|1357959_1358670_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	4.09575e-119
NZ_CP018648.1\|WP_001219253.1\|1357480_1357960_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	3.84083e-103
NZ_CP018648.1\|WP_000134246.1\|1356434_1357484_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP018648.1\|WP_000206417.1\|1367098_1368157_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.28543e-133
NZ_CP018648.1\|WP_000281483.1\|1365709_1366360_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	7.7595e-75
NZ_CP018648.1\|WP_001145541.1\|1373396_1374350_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP018648.1\|WP_001092251.1\|1360156_1361596_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP018648.1\|WP_000490481.1\|1362764_1363811_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP018648.1\|WP_000117945.1\|1368170_1368725_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
NZ_CP018648.1\|WP_000085107.1\|1366341_1367088_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.16311e-46
NZ_CP018648.1\|WP_000029737.1\|1370289_1372953_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP018648.1\|WP_000517480.1\|1358688_1359000_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	1.08865e-64
NZ_CP018648.1\|WP_001173663.1\|1359564_1360170_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	4.61291e-146
NZ_CP018648.1\|WP_001118109.1\|1359190_1359547_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	4.85353e-49
NZ_CP018648.1\|WP_000368579.1\|1368721_1370278_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP018648.1\|WP_001518648.1\|1364499_1364793_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62

>NZ_CP018648.1|WP_000490481.1|1362764_1363811_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NZ_CP018648.1|WP_000372384.1|1361605_1362514_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NZ_CP018648.1|WP_001092251.1|1360156_1361596_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYCEETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NZ_CP018648.1|WP_001173663.1|1359564_1360170_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NZ_CP018648.1|WP_001118109.1|1359190_1359547_-|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>NZ_CP018648.1|WP_000517480.1|1358688_1359000_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NZ_CP018648.1|WP_000741653.1|1357959_1358670_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLTISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NZ_CP018648.1|WP_001219253.1|1357480_1357960_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRISYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NZ_CP018648.1|WP_000134246.1|1356434_1357484_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NZ_CP018648.1|WP_001221538.1|1355692_1356454_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>NZ_CP018648.1|WP_001518648.1|1364499_1364793_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>NZ_CP018648.1|WP_000144830.1|1364792_1365713_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPESLGDSGHRGHG
>NZ_CP018648.1|WP_000281483.1|1365709_1366360_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASTIFDVQTRPFAPMLSAGQTLRFNLRANPTICKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALEWLARQGEQNGFTLREASVDAYRQQQIRREKSRQMIQFSSVDYTGVLVINEPALFLQRLAQGYGKSRAFGCGMMMIKPGDDA
>NZ_CP018648.1|WP_000085107.1|1366341_1367088_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPLRSALLGLLAAALGIRRDEEERLNTFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGNAADVLREAYRWYQDQFNALKLTLPGLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NZ_CP018648.1|WP_000206417.1|1367098_1368157_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITALHENMNEVYAQETAFKNFNVMNQQGSMKDVLDFICA
>NZ_CP018648.1|WP_000117945.1|1368170_1368725_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>NZ_CP018648.1|WP_000368579.1|1368721_1370278_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP018648.1|WP_000029737.1|1370289_1372953_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NZ_CP018648.1|WP_001145541.1|1373396_1374350_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP018648.1|WP_000039870.1|1374437_1375172_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: NZ_CP018648_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018648_2

1380555-1381255

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CNGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
GTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

11 spacers

cas3,cas8e,cse2gr11,cas7

The CRISPR arrays of NZ_CP018648_2

>merge|NZ_CP018648|2|1380555-1381255|CRISPRCasFinder,CRT,PILER-CR
ACGGCTATCCTTGTTGGCGCGGGGAACACGGCTACACGCAAAAATTCCAGTCGTTGGCGCACGGTTTATCCCCGCTGGCGCGGGGAACACCCGATTAAGATCCGCAGTCTGCATCAGTAACTCGGTTTATCCCCGCTGGCGAGGGGAACACCGATTCTACGGCAACAGGCCAGGCTGCGACCGCGGTTTATCCCCGCTGGCGCGGGGAACACATCAAACATGGAAACCCCTTTAATGAGAGCAACGGTTTATCCCCGCTGGCGCGGGGAACACTCAGGAACGCGCGGCGGAAGAGCTTGGTGTTTGCGGTTTATCCCCGCTGGCGCGGGGAACACGCTGCCTTTCCCGGAGTTCCGGCCCCTAAATTGGGTTTATCCCCGCTGGCGCGGGGAACACTCATGCGCTATAAAAATCAGACTGTCACATGCCGGTTTATCCCCGCTGGCGCGGGGAACACTGATTATTGACGACAACAGCACAGACCGGCAGCAGTTTATCCCCGCTGGCGCGGGGAACACAATAATCGGCAATTTGTCCTGGACAGGCACGGCAGTTTATCCCCGCTGGCGCGGGGAACACAATAATCGGCAATTTGTCCTGGACAGGCACGGCAGTTTATCCCCGCTGGCGCGGGGAACACGAATCTGGAGGCCAACAGCGCGGCGAAATCCTCAGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP018648|2|2|1380555-1381255|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGATTAAGATCCGCAGTCTGCATCAGTAACT
CGGTTTATCCCCGCTGGCGAGGGGAACAC	CGATTCTACGGCAACAGGCCAGGCTGCGACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCAAACATGGAAACCCCTTTAATGAGAGCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCAGGAACGCGCGGCGGAAGAGCTTGGTGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTGCCTTTCCCGGAGTTCCGGCCCCTAAATT
GGGTTTATCCCCGCTGGCGCGGGGAACAC	TCATGCGCTATAAAAATCAGACTGTCACATGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATTATTGACGACAACAGCACAGACCGGCAG
CAGTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGG
CAGTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGG
CAGTTTATCCCCGCTGGCGCGGGGAACAC	GAATCTGGAGGCCAACAGCGCGGCGAAATCCT
CAGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP018648|2|2|1380555-1381255|CRT
ACGGCTATCCTTGTTGGCGCGGGGAACAC	GGCTACACGCAAAAATTCCAGTCGTTGGCGCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGATTAAGATCCGCAGTCTGCATCAGTAACT
CGGTTTATCCCCGCTGGCGAGGGGAACAC	CGATTCTACGGCAACAGGCCAGGCTGCGACCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCAAACATGGAAACCCCTTTAATGAGAGCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCAGGAACGCGCGGCGGAAGAGCTTGGTGTTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCTGCCTTTCCCGGAGTTCCGGCCCCTAAATT
GGGTTTATCCCCGCTGGCGCGGGGAACAC	TCATGCGCTATAAAAATCAGACTGTCACATGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATTATTGACGACAACAGCACAGACCGGCAG
CAGTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGG
CAGTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGG
CAGTTTATCCCCGCTGGCGCGGGGAACAC	GAATCTGGAGGCCAACAGCGCGGCGAAATCCT
CAGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP018648|2|2|1380618-1381255|PILER-CR
GTTTATCCCCGCTGGCGCGGGGAACAC	CCGATTAAGATCCGCAGTCTGCATCAGTAACTCG
GTTTATCCCCGCTGGCGAGGGGAACAC	CGATTCTACGGCAACAGGCCAGGCTGCGACCGCG
GTTTATCCCCGCTGGCGCGGGGAACAC	ATCAAACATGGAAACCCCTTTAATGAGAGCAACG
GTTTATCCCCGCTGGCGCGGGGAACAC	TCAGGAACGCGCGGCGGAAGAGCTTGGTGTTTGCG
GTTTATCCCCGCTGGCGCGGGGAACAC	GCTGCCTTTCCCGGAGTTCCGGCCCCTAAATTGG
GTTTATCCCCGCTGGCGCGGGGAACAC	TCATGCGCTATAAAAATCAGACTGTCACATGCCG
GTTTATCCCCGCTGGCGCGGGGAACAC	TGATTATTGACGACAACAGCACAGACCGGCAGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	AATAATCGGCAATTTGTCCTGGACAGGCACGGCA
GTTTATCCCCGCTGGCGCGGGGAACAC	GAATCTGGAGGCCAACAGCGCGGCGAAATCCTCA
GTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018648.1\|WP_001044459.1\|1390390_1391164_+\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|185177
NZ_CP018648.1\|WP_000108313.1\|1379208_1379571_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP018648.1\|WP_000039870.1\|1374437_1375172_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP018648.1\|WP_000210451.1\|1385604_1386405_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP018648.1\|WP_001290670.1\|1375273_1376986_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP018648.1\|WP_001079646.1\|1392171_1392708_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185168
NZ_CP018648.1\|WP_000206417.1\|1367098_1368157_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP018648.1\|WP_000178270.1\|1391183_1391690_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
NZ_CP018648.1\|WP_001145541.1\|1373396_1374350_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP018648.1\|WP_000036734.1\|1382358_1383657_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP018648.1\|WP_000842512.1\|1387011_1387599_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185169
NZ_CP018648.1\|WP_000117945.1\|1368170_1368725_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP018648.1\|WP_000981797.1\|1387678_1390378_+\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|185176
NZ_CP018648.1\|WP_000029737.1\|1370289_1372953_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP018648.1\|WP_000210932.1\|1376985_1378785_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP018648.1\|WP_000832393.1\|1391704_1392175_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
NZ_CP018648.1\|WP_000210863.1\|1383739_1385377_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP018648.1\|WP_000368579.1\|1368721_1370278_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP018648.1\|WP_001199961.1\|1381551_1382223_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP018648.1\|WP_001207998.1\|1379658_1380456_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158

Protein	Function_ID	Function_description	E-value
NZ_CP018648.1\|WP_001044459.1\|1390390_1391164_+\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0
NZ_CP018648.1\|WP_000108313.1\|1379208_1379571_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NZ_CP018648.1\|WP_000039870.1\|1374437_1375172_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.73232e-139
NZ_CP018648.1\|WP_000210451.1\|1385604_1386405_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
NZ_CP018648.1\|WP_001290670.1\|1375273_1376986_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP018648.1\|WP_001079646.1\|1392171_1392708_+\|fimbrial-protein	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	7.785e-121
NZ_CP018648.1\|WP_000206417.1\|1367098_1368157_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.28543e-133
NZ_CP018648.1\|WP_000178270.1\|1391183_1391690_+\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	4.31975e-105
NZ_CP018648.1\|WP_001145541.1\|1373396_1374350_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP018648.1\|WP_000036734.1\|1382358_1383657_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP018648.1\|WP_000842512.1\|1387011_1387599_+\|fimbrial-protein	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	5.36845e-100
NZ_CP018648.1\|WP_000117945.1\|1368170_1368725_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.26497e-33
NZ_CP018648.1\|WP_000981797.1\|1387678_1390378_+\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|185176	PRK15273, PRK15273, fimbrial biogenesis outer membrane usher protein.	0
NZ_CP018648.1\|WP_000029737.1\|1370289_1372953_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP018648.1\|WP_000210932.1\|1376985_1378785_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP018648.1\|WP_000832393.1\|1391704_1392175_+\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	2.10162e-98
NZ_CP018648.1\|WP_000210863.1\|1383739_1385377_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP018648.1\|WP_000368579.1\|1368721_1370278_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP018648.1\|WP_001199961.1\|1381551_1382223_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
NZ_CP018648.1\|WP_001207998.1\|1379658_1380456_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.00381e-102

>NZ_CP018648.1|WP_001207998.1|1379658_1380456_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGKNFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NZ_CP018648.1|WP_000108313.1|1379208_1379571_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NZ_CP018648.1|WP_000210932.1|1376985_1378785_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGVVAVTPVPERKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLIATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAEALIGLLRPLTPRLYSIASAQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIDLAWSRDQKEKIYVQDKLREQGAELWCWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NZ_CP018648.1|WP_001290670.1|1375273_1376986_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVAITDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP018648.1|WP_000039870.1|1374437_1375172_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELKAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP018648.1|WP_001145541.1|1373396_1374350_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTWHPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP018648.1|WP_000029737.1|1370289_1372953_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYMLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPYSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERCVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQTLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQEGKFYCDRAFAGQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDSVVTPYASGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDFAACGYSANEGLIGMMGE
>NZ_CP018648.1|WP_000368579.1|1368721_1370278_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVDLADENVVDIAATRADLQGAAWQFLLGLLQCSIAPKRYKNWEDIWFDGLHADVLHKALAPLEHAFQFGAESPSFMQDFEPLSGEKVSIASLLPEIPGAQTTKFNKDHFVKRGVTERFCPHCAALALFSLQLNAPAGGKGYRTGLRGGGPLTTLVELQEYQGERQTPIWRKLWLNVMPQDTADLPLPDQCDATVFPWLAATRTSEQANAVTTPEQVNKLQAYWGMPRRIRLDFATLQSGCCDICGAESDELLGFMTVKNYGVNYDGWRHPLTPYRAPVKDQNAFFSVKPQPGGLIWRDWLGLSQNNQTEANYESPAQVVKVFNARSLTDVKAGIRGFGADFDNMKIRCWYEHHFPLLMTEGLIPDLRKAVQTAARLLSLLRSALKEAWFTNAKDARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP018648.1|WP_000117945.1|1368170_1368725_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSVVTKDDKATLRQWHDELQEKRGLRASLRRSKTVNDACLAEGLHSLLMQTHSLWKNKAPWNVTALAITAALAAHIKFIDEQKSFAAQLGQKKGGDTPVMSKLRFSHLLAVKTPDELLRQLRRAVKLLDGSVNLFSLADDIFCWCQEQNDLLNHHRRQQRPTEFLRIRWALEYYQAGDTDNEQD
>NZ_CP018648.1|WP_000206417.1|1367098_1368157_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRISSQSLKRAWRTSELFEQALAGHIGIRTGRIAREAAQILVDSGIDAKKAVEYVKNIANCFGKVKEDKKPKDELTNAETEQLVHISPAEFEAVKALARRLAEEKRPATEEEAELLRHDRMAVDIAMFGRMLAKKTDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITALHENMNEVYAQETAFKNFNVMNQQGSMKDVLDFICA
>NZ_CP018648.1|WP_001199961.1|1381551_1382223_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP018648.1|WP_000036734.1|1382358_1383657_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP018648.1|WP_000210863.1|1383739_1385377_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>NZ_CP018648.1|WP_000210451.1|1385604_1386405_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NZ_CP018648.1|WP_000842512.1|1387011_1387599_+|fimbrial-protein
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>NZ_CP018648.1|WP_000981797.1|1387678_1390378_+|fimbrial-biogenesis-outer-membrane-usher-protein
MMNNTWKSVLCPIACGVGMLLSLSPYSASGKDIEFNTDFLDVKNRDNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVTQLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDWDPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQASYDHRDDDENTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVVSDDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTLHVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASWGVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQGNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVTYNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYNGDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQGAQADGYYSHQGALTDIDLSADYEEGSYRSLGMSLRGGMTLTTQGGALHRGSLAGSTRLLVDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWLAGVKAGETLKVFWDGAAQCEASLPSTFTPELLANALLLPCKMLEGQPPTAPQKSSPLPAQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME
>NZ_CP018648.1|WP_001044459.1|1390390_1391164_+|fimbria/pilus-periplasmic-chaperone
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>NZ_CP018648.1|WP_000178270.1|1391183_1391690_+|fimbrial-protein
MTMLTRWKMLVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCTVGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>NZ_CP018648.1|WP_000832393.1|1391704_1392175_+|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGEMLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTSVPELGIELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>NZ_CP018648.1|WP_001079646.1|1392171_1392708_+|fimbrial-protein
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFSGSATVSFEYQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018648_2	2.5\|1380828\|33\|NZ_CP018648\|CRISPRCasFinder,CRT	1380828-1380860	33	NZ_CP032236	Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence	63403-63435	4	0.879
NZ_CP018648_2	2.5\|1380828\|33\|NZ_CP018648\|CRISPRCasFinder,CRT	1380828-1380860	33	NZ_LN681230	Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence	91355-91387	4	0.879
NZ_CP018648_2	2.15\|1380828\|35\|NZ_CP018648\|PILER-CR	1380828-1380862	35	NZ_CP032236	Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence	63403-63437	5	0.857
NZ_CP018648_2	2.15\|1380828\|35\|NZ_CP018648\|PILER-CR	1380828-1380862	35	NZ_LN681230	Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence	91353-91387	5	0.857
NZ_CP018648_2	2.16\|1380890\|34\|NZ_CP018648\|PILER-CR	1380890-1380923	34	NZ_CP044178	Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1	18967-19000	5	0.853
NZ_CP018648_2	2.16\|1380890\|34\|NZ_CP018648\|PILER-CR	1380890-1380923	34	CP053324	Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence	25136-25169	5	0.853
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP044178	Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1	18969-19000	6	0.812
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	CP053324	Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence	25138-25169	6	0.812
NZ_CP018648_2	2.16\|1380890\|34\|NZ_CP018648\|PILER-CR	1380890-1380923	34	NZ_LN890526	Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence	31716-31749	6	0.824
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_LN890526	Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence	31718-31749	7	0.781
NZ_CP018648_2	2.3\|1380706\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380706-1380737	32	MN694003	Marine virus AFVG_250M677, complete genome	17629-17660	8	0.75
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP053022	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence	329022-329053	8	0.75
NZ_CP018648_2	2.8\|1381012\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1381012-1381043	32	MG592432	Vibrio phage 1.050.O._10N.286.48.A6, partial genome	21687-21718	8	0.75
NZ_CP018648_2	2.8\|1381012\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1381012-1381043	32	MG592431	Vibrio phage 1.049.O._10N.286.54.B5, partial genome	21426-21457	8	0.75
NZ_CP018648_2	2.13\|1380706\|34\|NZ_CP018648\|PILER-CR	1380706-1380739	34	MN694003	Marine virus AFVG_250M677, complete genome	17627-17660	8	0.765
NZ_CP018648_1	1.1\|1363855\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1363855-1363886	32	NZ_MG266000	Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence	5501-5532	9	0.719
NZ_CP018648_1	1.3\|1363977\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1363977-1364008	32	MK449011	Streptococcus phage Javan92, complete genome	36157-36188	9	0.719
NZ_CP018648_1	1.3\|1363977\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1363977-1364008	32	MK448835	Streptococcus phage Javan93, complete genome	36157-36188	9	0.719
NZ_CP018648_1	1.3\|1363977\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1363977-1364008	32	MK448836	Streptococcus phage Javan95, complete genome	37400-37431	9	0.719
NZ_CP018648_1	1.3\|1363977\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1363977-1364008	32	MK448825	Streptococcus phage Javan639, complete genome	37400-37431	9	0.719
NZ_CP018648_1	1.7\|1364221\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1364221-1364252	32	KY006853	Erythrobacter phage vB_EliS_R6L, complete genome	41418-41449	9	0.719
NZ_CP018648_1	1.10\|1363857\|32\|NZ_CP018648\|PILER-CR	1363857-1363888	32	NZ_MG266000	Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence	5501-5532	9	0.719
NZ_CP018648_1	1.12\|1363979\|32\|NZ_CP018648\|PILER-CR	1363979-1364010	32	MK449011	Streptococcus phage Javan92, complete genome	36157-36188	9	0.719
NZ_CP018648_1	1.12\|1363979\|32\|NZ_CP018648\|PILER-CR	1363979-1364010	32	MK448835	Streptococcus phage Javan93, complete genome	36157-36188	9	0.719
NZ_CP018648_1	1.12\|1363979\|32\|NZ_CP018648\|PILER-CR	1363979-1364010	32	MK448836	Streptococcus phage Javan95, complete genome	37400-37431	9	0.719
NZ_CP018648_1	1.12\|1363979\|32\|NZ_CP018648\|PILER-CR	1363979-1364010	32	MK448825	Streptococcus phage Javan639, complete genome	37400-37431	9	0.719
NZ_CP018648_1	1.16\|1364223\|32\|NZ_CP018648\|PILER-CR	1364223-1364254	32	KY006853	Erythrobacter phage vB_EliS_R6L, complete genome	41418-41449	9	0.719
NZ_CP018648_2	2.5\|1380828\|33\|NZ_CP018648\|CRISPRCasFinder,CRT	1380828-1380860	33	NZ_CP031947	Ruegeria sp. AD91A plasmid unnamed1, complete sequence	143751-143783	9	0.727
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP048340	Escherichia coli strain 142 plasmid p142_C, complete sequence	2410-2441	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_LR130559	Escherichia coli strain MS14385 isolate MS14385 plasmid 5	41882-41913	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP020518	Escherichia coli strain 222 plasmid unnamed2, complete sequence	13450-13481	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP020497	Escherichia coli strain 103 plasmid unnamed2, complete sequence	37140-37171	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP040921	Escherichia coli strain FC853_EC plasmid p853EC2, complete sequence	32060-32091	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	CP053252	Escherichia coli strain SCU-204 plasmid pSCU-204-5, complete sequence	19381-19412	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP042622	Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-7, complete sequence	2614-2645	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_LT985302	Escherichia coli strain ECOR 39 genome assembly, plasmid: RCS82_pI	11943-11974	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP028194	Escherichia coli strain CFSAN018748 plasmid pGMI14-004_3, complete sequence	15383-15414	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP024865	Escherichia coli strain AR_0015 plasmid unitig_3_pilon, complete sequence	22646-22677	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	AP019710	Escherichia coli O145:H28 122715 plasmid pO145_122715_2 DNA, complete genome	4361-4392	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP024829	Escherichia coli strain CREC-544 plasmid pCREC-544_3, complete sequence	2221-2252	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP009861	Escherichia coli strain ECONIH1 plasmid pECO-b75, complete sequence	2868-2899	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	CP025877	Escherichia coli strain 503458 plasmid p503458_49, complete sequence	18343-18374	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP023368	Escherichia coli strain 1428 plasmid p48, complete sequence	4914-4945	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP032259	Escherichia coli strain AR_0067 plasmid unnamed2, complete sequence	23402-23433	9	0.719
NZ_CP018648_2	2.6\|1380890\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380890-1380921	32	NZ_CP037450	Escherichia coli strain ATCC 25922 plasmid unnamed, complete sequence	15851-15882	9	0.719
NZ_CP018648_2	2.8\|1381012\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1381012-1381043	32	NC_047790	Pseudoalteromonas phage C5a, complete genome	34441-34472	9	0.719
NZ_CP018648_2	2.11\|1381195\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1381195-1381226	32	CP006879	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence	405613-405644	9	0.719
NZ_CP018648_2	2.4\|1380767\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1380767-1380798	32	NZ_LR134399	Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence	103231-103262	10	0.688
NZ_CP018648_2	2.11\|1381195\|32\|NZ_CP018648\|CRISPRCasFinder,CRT	1381195-1381226	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	699963-699994	10	0.688
NZ_CP018648_2	2.15\|1380828\|35\|NZ_CP018648\|PILER-CR	1380828-1380862	35	NZ_CP031947	Ruegeria sp. AD91A plasmid unnamed1, complete sequence	143751-143785	11	0.686

1. spacer 2.5|1380828|33|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP032236 (Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence) position: , mismatch: 4, identity: 0.879

tcaggaacgcgcggcggaagagcttggtgtttg	CRISPR spacer
tcaggaacgcgcagcggaagagcttggtaaatg	Protospacer
************.***************.  **

2. spacer 2.5|1380828|33|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_LN681230 (Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence) position: , mismatch: 4, identity: 0.879

tcaggaacgcgcggcggaagagcttggtgtttg	CRISPR spacer
tcaggaacgcgcagcggaagagcttggtaaatg	Protospacer
************.***************.  **

3. spacer 2.15|1380828|35|NZ_CP018648|PILER-CR matches to NZ_CP032236 (Yersinia ruckeri strain NHV_3758 plasmid pYR4, complete sequence) position: , mismatch: 5, identity: 0.857

tcaggaacgcgcggcggaagagcttggtgtttgcg	CRISPR spacer
tcaggaacgcgcagcggaagagcttggtaaatgcc	Protospacer
************.***************.  ***

4. spacer 2.15|1380828|35|NZ_CP018648|PILER-CR matches to NZ_LN681230 (Yersinia ruckeri strain CSF007-82 plasmid pYR3, complete sequence) position: , mismatch: 5, identity: 0.857

tcaggaacgcgcggcggaagagcttggtgtttgcg	CRISPR spacer
tcaggaacgcgcagcggaagagcttggtaaatgcc	Protospacer
************.***************.  ***

5. spacer 2.16|1380890|34|NZ_CP018648|PILER-CR matches to NZ_CP044178 (Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1) position: , mismatch: 5, identity: 0.853

gctgcctttcccggagttccggcccct----aaattgg	CRISPR spacer
ggtgcctttcccggagttccggccccttctcaaa----	Protospacer
* *************************    ***

6. spacer 2.16|1380890|34|NZ_CP018648|PILER-CR matches to CP053324 (Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.853

gctgcctttcccggagttccggcccct----aaattgg	CRISPR spacer
ggtgcctttcccggagttccggccccttctcaaa----	Protospacer
* *************************    ***

7. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP044178 (Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1) position: , mismatch: 6, identity: 0.812

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
ggtgcctttcccggagttccggccccttctca	Protospacer
* *************************   .

8. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to CP053324 (Salmonella enterica subsp. salamae serovar 40:c:e,n,z15 strain 2013K-0524 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
ggtgcctttcccggagttccggccccttctca	Protospacer
* *************************   .

9. spacer 2.16|1380890|34|NZ_CP018648|PILER-CR matches to NZ_LN890526 (Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence) position: , mismatch: 6, identity: 0.824

gctgcctttcccggagttccggcccct----aaattgg	CRISPR spacer
ggtgccttttccggagttccggccccttctcaaa----	Protospacer
* *******.*****************    ***

10. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_LN890526 (Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 plasmid 3, complete sequence) position: , mismatch: 7, identity: 0.781

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
ggtgccttttccggagttccggccccttctca	Protospacer
* *******.*****************   .

11. spacer 2.3|1380706|32|NZ_CP018648|CRISPRCasFinder,CRT matches to MN694003 (Marine virus AFVG_250M677, complete genome) position: , mismatch: 8, identity: 0.75

cgattctacggcaacaggccaggctgcgaccg	CRISPR spacer
ggcgagcacggcaacagcccaggctgcgatcg	Protospacer
 *    .********** ***********.**

12. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP053022 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence) position: , mismatch: 8, identity: 0.75

gctgcctttcccggagttccggcccctaaatt---	CRISPR spacer
tatgcctttcccggctttccggccc---aactgac	Protospacer
  ************  *********   **.*

13. spacer 2.8|1381012|32|NZ_CP018648|CRISPRCasFinder,CRT matches to MG592432 (Vibrio phage 1.050.O._10N.286.48.A6, partial genome) position: , mismatch: 8, identity: 0.75

tgattattgacgacaacagcacagaccggcag	CRISPR spacer
ttataattgactacaacagcacagagcagatt	Protospacer
* ** ****** ************* *.*

14. spacer 2.8|1381012|32|NZ_CP018648|CRISPRCasFinder,CRT matches to MG592431 (Vibrio phage 1.049.O._10N.286.54.B5, partial genome) position: , mismatch: 8, identity: 0.75

tgattattgacgacaacagcacagaccggcag	CRISPR spacer
ttataattgactacaacagcacagagcagatt	Protospacer
* ** ****** ************* *.*

15. spacer 2.13|1380706|34|NZ_CP018648|PILER-CR matches to MN694003 (Marine virus AFVG_250M677, complete genome) position: , mismatch: 8, identity: 0.765

cgattctacggcaacaggccaggctgcgaccgcg	CRISPR spacer
ggcgagcacggcaacagcccaggctgcgatcgcg	Protospacer
 *    .********** ***********.****

16. spacer 1.1|1363855|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_MG266000 (Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence) position: , mismatch: 9, identity: 0.719

tatttataagcgtgtcatctatgcaacccaac	CRISPR spacer
aatttataatcatgtcatctatgccataattc	Protospacer
 ******** *.************ *.    *

17. spacer 1.3|1363977|32|NZ_CP018648|CRISPRCasFinder,CRT matches to MK449011 (Streptococcus phage Javan92, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

18. spacer 1.3|1363977|32|NZ_CP018648|CRISPRCasFinder,CRT matches to MK448835 (Streptococcus phage Javan93, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

19. spacer 1.3|1363977|32|NZ_CP018648|CRISPRCasFinder,CRT matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

20. spacer 1.3|1363977|32|NZ_CP018648|CRISPRCasFinder,CRT matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

21. spacer 1.7|1364221|32|NZ_CP018648|CRISPRCasFinder,CRT matches to KY006853 (Erythrobacter phage vB_EliS_R6L, complete genome) position: , mismatch: 9, identity: 0.719

gagaatgctcatgcgcgtgagcgccatatatt	CRISPR spacer
cgaaatgatcatgcgcgtcagcgccattgcgt	Protospacer
 ..**** ********** ********    *

22. spacer 1.10|1363857|32|NZ_CP018648|PILER-CR matches to NZ_MG266000 (Clostridioides difficile strain 7032985 plasmid pCD-ISS1, complete sequence) position: , mismatch: 9, identity: 0.719

tatttataagcgtgtcatctatgcaacccaac	CRISPR spacer
aatttataatcatgtcatctatgccataattc	Protospacer
 ******** *.************ *.    *

23. spacer 1.12|1363979|32|NZ_CP018648|PILER-CR matches to MK449011 (Streptococcus phage Javan92, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

24. spacer 1.12|1363979|32|NZ_CP018648|PILER-CR matches to MK448835 (Streptococcus phage Javan93, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

25. spacer 1.12|1363979|32|NZ_CP018648|PILER-CR matches to MK448836 (Streptococcus phage Javan95, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

26. spacer 1.12|1363979|32|NZ_CP018648|PILER-CR matches to MK448825 (Streptococcus phage Javan639, complete genome) position: , mismatch: 9, identity: 0.719

ggccgctggtcaaattcccaatctgagcaatc	CRISPR spacer
tacatcttgacaaattcccaatctgagcgact	Protospacer
 .*  ** * ******************.*..

27. spacer 1.16|1364223|32|NZ_CP018648|PILER-CR matches to KY006853 (Erythrobacter phage vB_EliS_R6L, complete genome) position: , mismatch: 9, identity: 0.719

gagaatgctcatgcgcgtgagcgccatatatt	CRISPR spacer
cgaaatgatcatgcgcgtcagcgccattgcgt	Protospacer
 ..**** ********** ********    *

28. spacer 2.5|1380828|33|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP031947 (Ruegeria sp. AD91A plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

tcaggaacgcgcggcggaagagcttggtgtttg	CRISPR spacer
ctttgcccgtgcggcggaagaccttggtgtttc	Protospacer
..  *  **.*********** **********

29. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP048340 (Escherichia coli strain 142 plasmid p142_C, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

30. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_LR130559 (Escherichia coli strain MS14385 isolate MS14385 plasmid 5) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

31. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP020518 (Escherichia coli strain 222 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

32. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP020497 (Escherichia coli strain 103 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

33. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP040921 (Escherichia coli strain FC853_EC plasmid p853EC2, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

34. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to CP053252 (Escherichia coli strain SCU-204 plasmid pSCU-204-5, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

35. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP042622 (Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-7, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

36. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_LT985302 (Escherichia coli strain ECOR 39 genome assembly, plasmid: RCS82_pI) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

37. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP028194 (Escherichia coli strain CFSAN018748 plasmid pGMI14-004_3, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

38. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP024865 (Escherichia coli strain AR_0015 plasmid unitig_3_pilon, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

39. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to AP019710 (Escherichia coli O145:H28 122715 plasmid pO145_122715_2 DNA, complete genome) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

40. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP024829 (Escherichia coli strain CREC-544 plasmid pCREC-544_3, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

41. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP009861 (Escherichia coli strain ECONIH1 plasmid pECO-b75, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

42. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to CP025877 (Escherichia coli strain 503458 plasmid p503458_49, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

43. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP023368 (Escherichia coli strain 1428 plasmid p48, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

44. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP032259 (Escherichia coli strain AR_0067 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

45. spacer 2.6|1380890|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP037450 (Escherichia coli strain ATCC 25922 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gctgcctttcccggagttccggcccctaaatt	CRISPR spacer
gtgccctttaccggagttccggccccttctca	Protospacer
*.  ***** *****************   .

46. spacer 2.8|1381012|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NC_047790 (Pseudoalteromonas phage C5a, complete genome) position: , mismatch: 9, identity: 0.719

tgattattgacgacaacagcacagaccggcag	CRISPR spacer
agcttattgacgaaaacggcacagacaccaaa	Protospacer
 * ********** ***.********    *.

47. spacer 2.11|1381195|32|NZ_CP018648|CRISPRCasFinder,CRT matches to CP006879 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602b, complete sequence) position: , mismatch: 9, identity: 0.719

gaatctggaggccaacagcgcggcgaaatcct	CRISPR spacer
gaatctggagggcgacagcgcggtcgaccctg	Protospacer
*********** *.*********. .* .*.

48. spacer 2.4|1380767|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_LR134399 (Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.688

atcaaacatggaaacccctttaatgagagcaa	CRISPR spacer
ctaaaacatggaaaccactgtaatgacgaatc	Protospacer
 * ************* ** ****** ..

49. spacer 2.11|1381195|32|NZ_CP018648|CRISPRCasFinder,CRT matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

gaatctggaggccaacagcgcggcgaaatcct	CRISPR spacer
gtggtcataggccatcagcgcggcgatatccc	Protospacer
* . ... ****** *********** ****.

50. spacer 2.15|1380828|35|NZ_CP018648|PILER-CR matches to NZ_CP031947 (Ruegeria sp. AD91A plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.686

tcaggaacgcgcggcggaagagcttggtgtttgcg	CRISPR spacer
ctttgcccgtgcggcggaagaccttggtgtttctc	Protospacer
..  *  **.*********** ********** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

173870 : 189985

Salmonella_phage(30.77%)

lysis,integrase,holin,tail

attL 170500:170529|attR 190121:190150

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
170500:170529	attL	NA	NA	NA	NA
WP_072100756.1\|173870_174734_-	DUF1983 domain-containing protein	K7PKJ2	Enterobacteria_phage	9.0e-48	78.9
WP_001152416.1\|177374_178070_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.0e-89	66.7
WP_000877926.1\|178159_178693_+	superoxide dismutase [Cu-Zn]	Q9MC02	Salmonella_phage	1.8e-46	54.0
WP_001541990.1\|179587_180067_-\|lysis	lysis protein	Q56118	Enterobacteria_phage	1.4e-55	77.0
WP_000984586.1\|180084_180537_-	lysozyme	A0A0M4R365	Salmonella_phage	2.3e-79	97.3
WP_001574216.1\|180520_180850_-\|holin	phage holin, lambda family	A0A0M3ULK9	Salmonella_phage	5.8e-56	100.0
WP_001574215.1\|181125_181812_+	PipA/GogA/GtgA family type III secretion system effector	Q9MBM0	Phage_Gifsy-2	1.8e-131	99.6
WP_000798708.1\|182172_182622_+	hypothetical protein	NA	NA	NA	NA
WP_001574213.1\|182995_183520_-	hypothetical protein	NA	NA	NA	NA
WP_001097218.1\|183616_184306_-	antitermination protein	I6PDF8	Cronobacter_phage	2.1e-60	54.9
WP_000784710.1\|184435_184663_-	DNA breaking-rejoining protein	A0A0M4RU10	Salmonella_phage	2.2e-14	66.7
WP_000940753.1\|184659_185259_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	4.7e-96	82.9
WP_000972675.1\|185322_185628_-	hypothetical protein	NA	NA	NA	NA
WP_001237395.1\|186259_188239_-	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	1.9e-162	46.3
WP_001575998.1\|188652_188931_+	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.4e-10	37.5
WP_000087636.1\|188905_189985_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	3.0e-101	52.5
190121:190150	attR	NA	NA	NA	NA

DBSCAN-SWA_2

362376 : 403074

Salmonella_phage(28.57%)

protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000938186.1\|362376_363057_+\|protease	type III secretion system effector protease PipA	Q9MBM0	Phage_Gifsy-2	2.2e-81	71.0
WP_000374046.1\|363675_364335_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	2.7e-44	52.4
WP_000904449.1\|364421_364751_+	sulfurtransferase TusE	NA	NA	NA	NA
WP_000072884.1\|364747_365029_-	acylphosphatase	NA	NA	NA	NA
WP_000548080.1\|365077_365857_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_000859416.1\|365882_366431_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_000140478.1\|366645_367857_+	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_000561983.1\|367914_368232_+	heat shock protein HspQ	NA	NA	NA	NA
WP_000975204.1\|368276_368693_-	CoA-binding protein	NA	NA	NA	NA
WP_000847719.1\|368863_369526_+	DUF2057 family protein	NA	NA	NA	NA
WP_000424187.1\|369620_370079_+	methylglyoxal synthase	NA	NA	NA	NA
WP_000420505.1\|370114_372169_-	DNA helicase IV	A7KV33	Bacillus_phage	8.5e-20	27.6
WP_001261222.1\|372292_372739_+	YccF domain-containing protein	NA	NA	NA	NA
WP_000950876.1\|372757_374911_+	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_001202375.1\|374897_375503_-	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_000288733.1\|375719_376229_+	cell division inhibitor SulA	NA	NA	NA	NA
WP_001674965.1\|376585_377638_+	porin OmpA	NA	NA	NA	NA
WP_000877172.1\|377709_378162_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_000156448.1\|378347_380108_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000227928.1\|380176_380695_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_001537784.1\|380794_380962_-	ribosome modulation factor	NA	NA	NA	NA
WP_000759136.1\|381217_381781_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_000433414.1\|381777_383418_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_000333139.1\|383422_384676_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_000053044.1\|384690_386598_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.4e-53	29.8
WP_001086485.1\|386610_388719_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_000224079.1\|388817_389927_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_001574119.1\|389923_390466_-	cell division protein ZapC	NA	NA	NA	NA
WP_000291723.1\|390631_391642_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_000193790.1\|391849_394462_-	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	6.3e-20	22.8
WP_000497441.1\|394888_395080_+	DinI-like family protein	S4TNM0	Salmonella_phage	6.2e-26	95.2
WP_001525490.1\|395350_396037_+	hypothetical protein	NA	NA	NA	NA
WP_000334547.1\|396396_397023_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	1.4e-66	63.2
WP_001674638.1\|397670_398639_-	SPI-2 type III secretion system effector SseI	Q9MBL9	Phage_Gifsy-2	3.0e-193	99.4
WP_072100753.1\|398864_399113_+\|tail	phage tail protein	A0A1B0VCD0	Salmonella_phage	2.1e-18	66.2
WP_000143167.1\|399116_399698_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	1.7e-95	89.5
WP_000583382.1\|399697_401407_-\|tail	tail fiber protein	A0A0U2SAV1	Escherichia_phage	1.5e-91	66.0
WP_000729406.1\|401403_402030_-	hypothetical protein	A0A0U2RK03	Escherichia_phage	3.3e-92	71.6
WP_000274547.1\|402013_402643_-	hypothetical protein	A0A0U2RJZ0	Escherichia_phage	1.6e-75	65.9
WP_001676370.1\|402663_403074_+	enterohemolysin	H6WRX0	Salmonella_phage	5.0e-33	100.0

DBSCAN-SWA_3

474353 : 481666

Ralstonia_phage(16.67%)

integrase,protease

attL 469150:469164|attR 480402:480416

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
469150:469164	attL	NA	NA	NA	NA
WP_001539594.1\|474353_474731_+\|integrase	integrase	A0A077KET4	Ralstonia_phage	1.2e-20	41.0
WP_001117984.1\|474892_475090_+	hypothetical protein	NA	NA	NA	NA
WP_000934064.1\|475302_477579_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.2e-165	42.3
WP_000520789.1\|477609_477930_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	4.5e-13	45.7
WP_000447499.1\|478253_478475_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
WP_000125875.1\|478604_480551_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.0e-39	43.1
480402:480416	attR	NA	NA	NA	NA
WP_001201751.1\|480547_481666_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.4e-08	38.9

DBSCAN-SWA_4

1105071 : 1202452

Salmonella_phage(81.13%)

terminase,tail,head,capsid,tRNA,plate,transposase,lysis,integrase,portal

attL 1120876:1120890|attR 1201357:1201371

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001128274.1\|1105071_1105815_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_000367631.1\|1105825_1106881_+	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_001670675.1\|1107413_1108145_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	6.4e-39	39.9
WP_000917872.1\|1108208_1108676_+	ribonuclease HI	J9Q745	Salmonella_phage	4.7e-51	58.9
WP_000801238.1\|1108672_1109395_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_001052774.1\|1109429_1110185_+	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_000644706.1\|1110256_1111624_+	murein transglycosylase D	A0A0A7NU10	Lactobacillus_phage	1.4e-10	33.0
WP_000207239.1\|1111679_1112450_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_001230970.1\|1112527_1113328_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_001127530.1\|1113459_1114635_-	MFS transporter	NA	NA	NA	NA
WP_000648524.1\|1114739_1115654_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000154868.1\|1115674_1116478_-	2,5-didehydrogluconate reductase DkgB	A0A1V0SDE7	Indivirus	1.6e-38	35.4
1120876:1120890	attL	NA	NA	NA	NA
WP_001235093.1\|1122482_1125056_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.0e-127	35.5
WP_000992636.1\|1125185_1125917_-	polyphenol oxidase	NA	NA	NA	NA
WP_000079130.1\|1125913_1126894_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000197660.1\|1127025_1127763_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000178449.1\|1128034_1128373_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_010989056.1\|1128476_1128524_+	hypothetical protein	NA	NA	NA	NA
WP_000200077.1\|1128623_1129784_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_000210984.1\|1129744_1130653_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_000225188.1\|1130710_1131832_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_001168062.1\|1131841_1132912_-	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	2.4e-90	51.8
WP_001212379.1\|1133351_1133870_+	YfiR family protein	NA	NA	NA	NA
WP_001030985.1\|1133862_1135083_+	diguanylate cyclase DgcN	A0A2K8I9Y5	Pseudomonas_phage	5.8e-08	36.2
WP_000065257.1\|1135239_1135587_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000469804.1\|1135627_1136395_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000043266.1\|1136439_1136988_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000256453.1\|1137006_1137255_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_000460052.1\|1137507_1138869_-	signal recognition particle protein	NA	NA	NA	NA
WP_001537507.1\|1139034_1139826_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_127172650.1\|1139845_1141132_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001287926.1\|1141252_1141858_+	hypothetical protein	NA	NA	NA	NA
WP_001518875.1\|1141892_1142483_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_001059151.1\|1142606_1143485_+	NAD(+) kinase	NA	NA	NA	NA
WP_000880965.1\|1143570_1145232_+	DNA repair protein RecN	NA	NA	NA	NA
WP_001203445.1\|1145380_1145719_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_001112990.1\|1145884_1146175_-	RnfH family protein	NA	NA	NA	NA
WP_000242603.1\|1146164_1146641_-	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_001518569.1\|1146790_1147273_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	5.2e-29	47.4
WP_001237693.1\|1147887_1159362_+	biofilm-associated protein BapA	NA	NA	NA	NA
WP_000533863.1\|1159426_1160836_+	TolC family outer membrane protein	NA	NA	NA	NA
WP_000196151.1\|1160832_1163013_+	type I secretion system permease/ATPase	F2Y302	Organic_Lake_phycodnavirus	1.3e-18	34.0
WP_012543392.1\|1163020_1164184_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_000980500.1\|1164735_1164954_-	hypothetical protein	E5G6Q4	Salmonella_phage	2.1e-38	100.0
WP_001102269.1\|1165022_1166123_-	phage late control D family protein	E5G6Q3	Salmonella_phage	2.6e-201	100.0
WP_000980411.1\|1166119_1166605_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	6.7e-77	100.0
WP_001282768.1\|1166601_1169409_-\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	99.9
WP_000763316.1\|1169401_1169521_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	1.8e-15	100.0
WP_001280963.1\|1169535_1169838_-\|tail	phage tail assembly protein	E5G6P9	Salmonella_phage	1.5e-45	100.0
WP_001207651.1\|1169892_1170408_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	9.3e-93	100.0
WP_000046108.1\|1170417_1171590_-\|tail	phage tail sheath protein	E5G6P7	Salmonella_phage	8.9e-224	100.0
WP_000974843.1\|1171692_1171917_-	helix-turn-helix domain-containing protein	E5G6P5	Salmonella_phage	1.5e-34	100.0
WP_000143187.1\|1172786_1173362_-\|tail	tail fiber assembly protein	E5G6P1	Salmonella_phage	4.3e-107	100.0
WP_001274649.1\|1173361_1175215_-\|tail	phage tail protein	E5G6P0	Salmonella_phage	0.0e+00	100.0
WP_001086804.1\|1175211_1175817_-\|tail	phage tail protein I	E5G6N9	Salmonella_phage	1.3e-117	100.0
WP_000268332.1\|1175809_1176718_-\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	5.4e-160	100.0
WP_000189373.1\|1176704_1177064_-\|plate	baseplate assembly protein	E5G6N7	Salmonella_phage	1.1e-60	100.0
WP_001672413.1\|1177060_1177639_-\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	1.4e-108	100.0
WP_000958562.1\|1177716_1178568_+	hypothetical protein	E5G6N5	Salmonella_phage	2.8e-163	100.0
WP_000343949.1\|1178569_1179016_-	phage virion morphogenesis protein	E5G6N4	Salmonella_phage	2.3e-71	99.3
WP_001039958.1\|1179008_1179440_-\|tail	phage tail protein	E5G6N3	Salmonella_phage	1.7e-76	100.0
WP_000196199.1\|1179535_1179964_-\|lysis	LysB family phage lysis regulatory protein	E5G6N2	Salmonella_phage	2.3e-68	100.0
WP_001069923.1\|1179960_1180476_-	lysozyme	E5G6N1	Salmonella_phage	5.3e-96	100.0
WP_000171565.1\|1180456_1180672_-	hypothetical protein	E5G6N0	Salmonella_phage	5.9e-33	100.0
WP_000868184.1\|1180675_1180879_-\|tail	tail protein X	E5G6M9	Salmonella_phage	3.8e-34	100.0
WP_000673537.1\|1180878_1181343_-\|head	head completion/stabilization protein	E5G6M8	Salmonella_phage	9.9e-86	100.0
WP_000059173.1\|1181436_1182087_-\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	4.9e-115	100.0
WP_000730759.1\|1182090_1183152_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	2.1e-195	100.0
WP_000216276.1\|1183168_1184002_-\|capsid	GPO family capsid scaffolding protein	E5G6M5	Salmonella_phage	3.1e-130	100.0
WP_001098395.1\|1184144_1185911_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	97.1
WP_001542203.1\|1185910_1186951_+\|portal	phage portal protein	E5G6M3	Salmonella_phage	5.5e-201	100.0
WP_001284991.1\|1187054_1188719_-	AIPR family protein	E5G6M2	Salmonella_phage	0.0e+00	100.0
WP_001673609.1\|1189032_1189710_-	hypothetical protein	NA	NA	NA	NA
WP_001217571.1\|1189823_1190057_-	DinI family protein	E5G6M1	Salmonella_phage	1.8e-35	98.7
WP_001154433.1\|1190067_1190256_-	hypothetical protein	E5G6M0	Salmonella_phage	1.4e-27	100.0
WP_000017507.1\|1190408_1192823_-	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	100.0
WP_000104187.1\|1192819_1193677_-	DNA adenine methylase	E5G6L8	Salmonella_phage	6.8e-165	100.0
WP_000752613.1\|1193673_1193901_-	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	2.7e-36	100.0
WP_001244219.1\|1193900_1194134_-	DUF2732 family protein	E5G6L6	Salmonella_phage	1.7e-33	100.0
WP_000963474.1\|1194201_1194543_-	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	1.2e-56	100.0
WP_000956190.1\|1194506_1194707_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	2.4e-33	100.0
WP_000460848.1\|1194714_1195224_-	phage regulatory CII family protein	E5G6L3	Salmonella_phage	1.5e-87	100.0
WP_000102105.1\|1195257_1195500_-	Rha family transcriptional regulator	A0A1S6KZZ6	Salmonella_phage	6.8e-38	97.5
WP_000932273.1\|1195621_1196254_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	6.3e-59	51.4
WP_000218402.1\|1196256_1197273_+\|integrase	site-specific integrase	E5G6L0	Salmonella_phage	5.0e-199	100.0
WP_000360326.1\|1197825_1198488_+	hypothetical protein	E5G6K9	Salmonella_phage	3.4e-124	100.0
WP_001142974.1\|1198749_1199343_+	hypothetical protein	NA	NA	NA	NA
WP_000445376.1\|1199741_1200545_+	DUF3800 domain-containing protein	Q19UP3	Mannheimia_phage	1.2e-62	44.7
WP_089113803.1\|1201340_1202452_-\|transposase	IS3-like element IS1351 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	7.6e-07	25.6
1201357:1201371	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3879126 : 3888297

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569168.1\|3879126_3880074_+	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	2.8e-10	27.8
WP_000824854.1\|3880057_3880789_+	ABC transporter permease	NA	NA	NA	NA
WP_001261696.1\|3880769_3880877_-	protein YohO	NA	NA	NA	NA
WP_001240421.1\|3880936_3881668_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	1.7e-100	87.4
WP_000272845.1\|3881890_3883576_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	6.2e-279	91.1
WP_000598637.1\|3883572_3884292_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000950414.1\|3884338_3884806_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	4.3e-73	89.7
WP_001197951.1\|3884862_3885393_-	YehR family lipoprotein	NA	NA	NA	NA
WP_000703145.1\|3885564_3886023_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	6.4e-53	72.5
WP_000195340.1\|3886263_3888297_-\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	6.1e-55	26.9

DBSCAN-SWA_6

3955494 : 3966001

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001144948.1\|3955494_3956898_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	4.0e-21	26.5
WP_000981469.1\|3957075_3957969_+	GalU regulator GalF	A0A127AW70	Bacillus_phage	4.8e-44	42.2
WP_000697848.1\|3958345_3959431_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.6e-102	53.9
WP_001023658.1\|3959430_3960330_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.1e-30	36.0
WP_000857535.1\|3960377_3961256_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.1e-108	65.5
WP_000973709.1\|3961256_3961808_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.3e-52	58.0
WP_000018223.1\|3961813_3962788_+	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_000648783.1\|3962803_3963577_+	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_000565913.1\|3963581_3964661_+	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.7e-16	24.5
WP_000126349.1\|3964687_3966001_+	lipopolysaccharide biosynthesis protein RfbH	H8ZJ36	Ostreococcus_tauri_virus	7.0e-52	35.1

DBSCAN-SWA_7

4622705 : 4638649

Escherichia_phage(62.5%)

tRNA,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001082296.1\|4622705_4623140_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	9.4e-30	52.1
WP_000159240.1\|4623189_4623528_-	EamA family transporter	NA	NA	NA	NA
WP_000802786.1\|4624373_4624919_-	glycoside hydrolase family 108 protein	A0A0U2S643	Escherichia_phage	2.3e-89	83.4
WP_000445513.1\|4624915_4625197_-\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	1.3e-16	49.4
WP_001688615.1\|4625186_4625375_-	hypothetical protein	Q8W636	Enterobacteria_phage	9.4e-11	57.4
WP_000900605.1\|4625296_4625692_-	tellurite resistance TerB family protein	Q71TK7	Escherichia_phage	4.7e-44	88.9
WP_000640113.1\|4627862_4628399_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.4e-70	70.9
WP_000774470.1\|4628395_4628686_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	5.1e-40	76.0
WP_000940751.1\|4628685_4629285_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	5.5e-97	82.9
WP_000882662.1\|4629808_4630021_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	2.5e-28	95.7
WP_000556389.1\|4630390_4631323_+	hypothetical protein	NA	NA	NA	NA
WP_001033796.1\|4631319_4631874_+	hypothetical protein	NA	NA	NA	NA
WP_001676916.1\|4632035_4632365_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	6.5e-23	51.7
WP_001227859.1\|4632637_4633105_+	helix-turn-helix domain-containing protein	A0A0U2QW76	Escherichia_phage	1.0e-53	66.9
WP_085981757.1\|4633489_4633645_+	DUF1391 family protein	M4QQ57	Salicola_phage	2.6e-06	48.9
WP_000004762.1\|4633752_4634274_-	hypothetical protein	NA	NA	NA	NA
WP_000560208.1\|4634711_4634933_+	cell division protein FtsZ	A0A0U2RTC4	Escherichia_phage	7.9e-33	83.6
WP_000800272.1\|4635017_4635335_+	hypothetical protein	NA	NA	NA	NA
WP_001676915.1\|4635362_4635980_+	exodeoxyribonuclease	A0A088CD28	Shigella_phage	2.5e-36	41.9
WP_001156217.1\|4636296_4637232_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	7.2e-144	97.3
WP_000123686.1\|4637275_4638649_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.1e-51	32.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018649

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP018650

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP018648

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection