CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP024701	Fusobacterium pseudoperiodonticum strain KCOM 1277 chromosome, complete genome	1 crisprs	cas14k,cas14j,PD-DExK,DEDDh,csa3,cas4,cas3,DinG,RT,WYL	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP024701_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP024701_1

1788067-1788160

Orphan

Consensus_repeat	Method
TTAATCTTTTCAATTTCTTCTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP024701_1

>merge|NZ_CP024701|1|1788067-1788160|CRISPRCasFinder
GTAACCTTTTCTATTTCTTCTCTACCTTGTGGGTCATTAATCCAATCAGCCATTTTTACCTCCTTGAAATTTTAATCTTTTCAATTTCTTCTAA

>NZ_CP024701|1|1|1788067-1788160|CRISPRCasFinder
GTAACCTTTTCTATTTCTTCTCT	ACCTTGTGGGTCATTAATCCAATCAGCCATTTTTACCTCCTTGAAATT
TTAATCTTTTCAATTTCTTCTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024701.1\|WP_099989564.1\|1796388_1796898_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989551.1\|1785271_1785631_-\|DUF1353-domain-containing-protein	unknown	unknown	gnl\|CDD\|377774
NZ_CP024701.1\|WP_099989561.1\|1794513_1794939_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989557.1\|1789859_1790198_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989554.1\|1787157_1787415_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989556.1\|1788723_1789863_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377414
NZ_CP024701.1\|WP_099989553.1\|1786334_1787081_-\|penicillin-binding-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989967.1\|1790819_1791680_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989562.1\|1794978_1795392_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371667
NZ_CP024701.1\|WP_099989559.1\|1791654_1791993_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989550.1\|1784788_1785271_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|377457
NZ_CP024701.1\|WP_099989558.1\|1790207_1790819_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375779
NZ_CP024701.1\|WP_099989552.1\|1785642_1786143_-\|M15-family-metallopeptidase	unknown	unknown	gnl\|CDD\|350620
NZ_CP024701.1\|WP_099958484.1\|1781481_1783818_-\|endonuclease-MutS2	unknown	unknown	gnl\|CDD\|224114
NZ_CP024701.1\|WP_099971502.1\|1779374_1780796_-\|cysteine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234705
NZ_CP024701.1\|WP_099989548.1\|1780810_1781506_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|133009
NZ_CP024701.1\|WP_153232672.1\|1784587_1784761_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989560.1\|1792615_1794367_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989563.1\|1795402_1796389_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP024701.1\|WP_099989549.1\|1784179_1784563_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP024701.1\|WP_099989551.1\|1785271_1785631_-\|DUF1353-domain-containing-protein	gnl\|CDD\|377774	pfam07087, DUF1353, Protein of unknown function (DUF1353). This family consists of several hypothetical bacterial proteins of around 100 residues in length. The function of this family is unknown.	7.45829e-38
NZ_CP024701.1\|WP_099989550.1\|1784788_1785271_-\|phage-holin-family-protein	gnl\|CDD\|377457	pfam05105, Phage_holin_4_1, Bacteriophage holin family. Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination. This family also includes TcdE/UtxA involved in toxin secretion in Clostridium difficile. The 1.E.10 family is represented by Bacillus subtilis phi29 holin; 1.E.16 represents the Cph1 holin; and the 1.E.19 family is represented by the Clostridium difficile TcdE holin. Toxigenic strains of C. difficile produce two large toxins (TcdA and TcdB) encoded within a pathogenicity locus. tcdE, encoded between tcdA and tcdB, encodes a 166 aa protein which causes death to E. coli when expressed, and the structure of TcdE resembles holins. TcdE acts on the bacterial membrane. Since TcdA and TcdB lack signal peptides, they may be released via TcdE either prior to or subsequent to cell lysis.	1.20518e-30
NZ_CP024701.1\|WP_099989552.1\|1785642_1786143_-\|M15-family-metallopeptidase	gnl\|CDD\|350620	cd14845, L-Ala-D-Glu_peptidase_like, L-Ala-D-Glu peptidase, also known as L-alanyl-D-glutamate endopeptidase. This L-Ala-D-Glu peptidase family includes L-alanyl-D-glutamate peptidase (bacteriophage T5) (also known as L-alanoyl-D-glutamate endopeptidase), and Ply118 and Ply500 L-Ala-D-Glu peptidase. Bacteriophage endolysin degrades the peptidoglycan of the bacterial host from within, leading to cell lysis and release of progeny virions. The bacteriophage endolysin Ply118 cleaves between L-Ala and D-Glu residues of Listeria cell wall peptidoglycan. This family belongs to the MEROPS peptidase M15 subfamily C.	2.96353e-28
NZ_CP024701.1\|WP_099958484.1\|1781481_1783818_-\|endonuclease-MutS2	gnl\|CDD\|224114	COG1193, COG1193, Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair].	0
NZ_CP024701.1\|WP_099971502.1\|1779374_1780796_-\|cysteine--tRNA-ligase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
NZ_CP024701.1\|WP_099989548.1\|1780810_1781506_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|133009	cd02516, CDP-ME_synthetase, CDP-ME synthetase is involved in mevalonate-independent isoprenoid production. 4-diphosphocytidyl-2-methyl-D-erythritol synthase (CDP-ME), also called 2C-methyl-d-erythritol 4-phosphate cytidylyltransferase catalyzes the third step in the alternative (non-mevalonate) pathway of Isopentenyl diphosphate (IPP) biosynthesis: the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate. This mevalonate independent pathway that utilizes pyruvate and glyceraldehydes 3-phosphate as starting materials for production of IPP occurs in a variety of bacteria, archaea and plant cells, but is absent in mammals. Thus, CDP-ME synthetase is an attractive targets for the structure-based design of selective antibacterial, herbicidal and antimalarial drugs.	1.31591e-85
NZ_CP024701.1\|WP_099989556.1\|1788723_1789863_-\|hypothetical-protein	gnl\|CDD\|377414	pfam04865, Baseplate_J, Baseplate J-like protein. The P2 bacteriophage J protein lies at the edge of the baseplate. This family also includes a number of bacterial homologs, which are thought to have been horizontally transferred.	3.17949e-13
NZ_CP024701.1\|WP_099989558.1\|1790207_1790819_-\|hypothetical-protein	gnl\|CDD\|375779	pfam18352, Gp138_N, Phage protein Gp138 N-terminal domain. This domain is found in the N-terminal domain of gene product 138 (gp138) in an unidentified bacteriophage. Gp138 is thought to be involved in the process of opening the host cell membrane during infection. The domain has an OB-fold with an intramolecular disulfide bond between C114 and C120.	5.14204e-10
NZ_CP024701.1\|WP_099989562.1\|1794978_1795392_-\|hypothetical-protein	gnl\|CDD\|371667	pfam11681, DUF3277, Protein of unknown function (DUF3277). This family of proteins represents a putative bacteriophage protein. No function is currently known.	0.00851834

>NZ_CP024701.1|WP_099989554.1|1787157_1787415_+|hypothetical-protein
MENLIKIDTGITGDYTNVGAYNFTFPKNYKQVLGVGVNVYKIGTATTLENVYLTGFNNTGFSFVKDCVEAARANTVKVAYTVFYV
>NZ_CP024701.1|WP_099989553.1|1786334_1787081_-|penicillin-binding-protein
MYYIYSKEKLPKLLFDVNLTSDEVKLYGGWDVIFGYYPNIQKDNSTIIERDTPFNYPIFDNNTIREMSRQEMVENDIEITLEVGEFIENKKLIKVPKPQGDNKYLNWDSQKHLWILDTEAQRKDYFDVIDNFKATSLEYGFDYKVGEKEHRQRCRDKDIIFIAMSALLLFLVKTFMNKEIKKTWYFEDNFGVSLDLMGFIQLMFFGSTFIQSVYDTENYFKTKVNPFPLTKDEFEKRRKEIHSSLAKG
>NZ_CP024701.1|WP_099989552.1|1785642_1786143_-|M15-family-metallopeptidase
MFSLSNTSIEKMNGVHPNVVNFMKELIKESPYDFKITCGVRTAEEQNREYQKGRTILYDSNGNKQQKVSWCDGYKLKSKHQIKIDGYGYAVDIAVLEKEKYTDKKTGEEKEKTVAKWDYKYYKAIYDVAKSKGLIDKYNIVWGGNWKQKDSVHFQLGTADNIQFKR
>NZ_CP024701.1|WP_099989551.1|1785271_1785631_-|DUF1353-domain-containing-protein
MEISKLKTMPIDDKYWEVMEDYFYQTSRGVIVVSKGFKTDYASVPRIFRNIINSYGKHGRGAVVHDWLYSSQCKTDITREEADKIFLEIMAECGVNKIKRNFMYRMVRIFGSSHFRRGE
>NZ_CP024701.1|WP_099989550.1|1784788_1785271_-|phage-holin-family-protein
MEDFFINAKNGIAMVWTGWISILVWALGGFDLSVKVLVFLMLVDYITGVWVGYITKTVNSTRAYRGISKKVFILIIVSCSTVIEQLVPNVGIRNLVIVFYVATEFLSVIENASKLGLPIPEKLKIALEQCKGDKCNSKCADDKNIKPEKLKEEDFDKEIK
>NZ_CP024701.1|WP_153232672.1|1784587_1784761_+|hypothetical-protein
MKIGNIKITLQGDENLKINFNGNIGITALDIMDKEEAKLFLMKEFKKILDENLEINE
>NZ_CP024701.1|WP_099989549.1|1784179_1784563_+|hypothetical-protein
MLIYSKQYLKNIYSPELIQFDVELRIKEIRKIYMEKIEEIKKYLNYRQKKTSDLSIINKIDKILEAVTSIISDKNFIKIKTLDISIEKNIMQIDIIVNTINEKSVQFNLDLKNNTLDIISKINSQIL
>NZ_CP024701.1|WP_099958484.1|1781481_1783818_-|endonuclease-MutS2
MNKHSFNVLEFDKLKELILENIVIDDNREVIENLEPYKDLSALNNELKTVKDFMDLLSFDGGFEAVGLRNINGLMDKIKLIGTYLEVEELWDINVNLRTVRVFKARLDELGKYKQLRDTIGNIPNLRMIEDVINKTINPEKEIKDDASLDLRDIRLHKKTLNMNIKRKFEELFDEPSLANAFQERIITERDGRMVTPVKFDFKGLIKGIEHDRSSSGQTVFIEPLSIVSLNNKMRELETKEKEEIRKILLRIAELLRNNRDDILTIGDKAMYLDILNAKSIYAVDNKCEIPTVSNREVLSLEKARHPFIDKDKVVPLTFEIGKDYDILLITGPNTGGKTVALKTAGLLTLMALSGIPIPASENSKIGFFEGVFADIGDEQSIEQSLSSFSAHLKNVKEILAGVTKNSLVLLDELGSGTDPIEGAAFAMAVIDYLNEKKAKSFITTHYSQVKAYGYNEEGIETASMEFNTDTLSPTYRLLVGIPGESNALTIAQRMGLPESIISKARAYISEDNKKVEKMIENIKTKSQELDEMRERFARLQEEARLDRERAKQETLIIEKQKNEIIKAAYEEAEKMMNEMRAKASALVEKIQHEEKNKEDAKQIQKNLNMLSTALREEKNKTVEVVKKIKTKVNFKVGDRVFVKSINQFANILKINTSKESASVQAGILKLEVPFEEIKIVEEKKEKVYNVSTHKKTPVRSEIDLRGKMVDEGIYELETYLDRATLNGYTEVYVIHGKGTGALREGILKYLKTSKYVKEYRIGGHGEGGLGCTVVTLK
>NZ_CP024701.1|WP_099989548.1|1780810_1781506_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MYSGDSKIEKKVTFILAAAGQGKRMNMSLAKQFLEYKGEPLFYSSLKIAFENQYIDDIIIVTNKENIKNIREFCENKKLLSKVKYIVEGGSERQYSIYNAIKKIENTDVVIIQDAARPFLKDKYIEESLKILDNTCDGVIIAVKCKDTIKVIDENGIIVETPNRNNLIAVHTPQTFKFEILKKAHQIAEEKNILATDDASLVENISGRIKFIHGDYDNIKITVQEDLKYLK
>NZ_CP024701.1|WP_099971502.1|1779374_1780796_-|cysteine--tRNA-ligase
MIKIYNTLTGHLDEFKPIKENEVSMYVCGPTVYNYIHIGNARPAIFFDTVRRYLEYRGYKVTYVQNFTDVDDKMINKANAENVSIKEIAERYIKAYFEDTAQINLKEDGMIRPKATDNIDGMINIIKSLVDKGYAYESNGDVYFEVKKYKEGYGELSKQNIEDLESGARIDVNEIKKDALDFALWKSSKPNEPSWDSPWGKGRPGWHIECSAMSRRYLGDSFDIHGGGLDLIFPHHENEMAQSKCGCGGTFARYWMHNGYININGEKMSKSSGSFVLLRDILKHFEGRVIRLFVLGSHYRKPMEFSDTELNQTKSSLERIENSLKRIKELNRENLDGTNDCQELLATKKEMEAKFIEAMDEDFNTAQALGHVFELVKSVNKALDEENFSKTAIEVLDEVYSYLVMIIEEVLGVKLKLEAEVNNISADLIELILELRKDAREQKNWALSDKIRDRLLELGIKIKDGKDKTTWTM
>NZ_CP024701.1|WP_099989556.1|1788723_1789863_-|hypothetical-protein
MITDKGFIVPTIDEIYTRKLNDFKSVKPDLRETDSNIIIAWLRFDSAEEYDSYLQALTAFNELSVYTATGSNLNAITSHLGMTWNKPKRAVGKITVTAEIGTQIPQAWGVETKSGIKFVTLNTSTVTTTQRETEIEVIALEGGTDGNVSSGAITEQTEILTGVISINNKLNTLGGKDLETDTELRERYLKRLDRKSSFTTEGIKNYILQNTNVKKCQVIENDTDTFDSDGRLAHSYECICYGDTNDNILKALYEYKIAGIRTVGAITKNFDEISVGFTRPTEKTVFLKVEIQGIKEVWKDEFKKTIKDIYLKYIDEVEPNSTIYLYKIIGEIYKNVGGIKTLRIKLGDTKYNEREQDYKLSTKEVAVANADDITIEVNL
>NZ_CP024701.1|WP_099989557.1|1789859_1790198_-|hypothetical-protein
MTSPKLDRDCELVFNDNGVCELVSNADDLVQAIRVELEQNKGQFALNTAWGTPYLNEANTGILQLKNNQSRIIQEVSRIINKYDGVQKIESIEFIDKELVINIKINGEVYTI
>NZ_CP024701.1|WP_099989558.1|1790207_1790819_-|hypothetical-protein
MIDVIKNMIDDSLNEVHTSLACKITSVNHSAGTCTVQPLAKRELCQQKIDYPPLIDVRLDFLKFGGWSFQIPRQVGDIVWVGFSETALSDETSLERFSLNEPYIIGSCESGYEANSDDIILQGAGTRIEIKGNGDITILAGSNETTITSNVTLNGNLTINGDTTQKGSITATGDVIGKGISLNNHTHNYNPGPSPETSTSKAK
>NZ_CP024701.1|WP_099989967.1|1790819_1791680_-|hypothetical-protein
MMKLWKQVRLITIGEIVFDYDELDVEFEVKCTDDNKSDLATIKIYNLSDTTLQKLKLNQDVSIDAGYRDIHGVIFNGIVESISTSRDENDFITTIEATPNNRAYANTIINRQFKAGIKASEVIKQIGTMCNFTMDIKELGKDTVYPNGKVFSGRLSNVIPILARDTGTISRFTNTTIEFKLPNKAYSSVLHLGAEQGLIRIDKKMDKADIKEKKGPQVESKNKSNVDKKISKSKFDLECLLVPLIKIGQLLEIESTLFKGRVVVKECSFVANGLESFTVLASVEVV
>NZ_CP024701.1|WP_099989559.1|1791654_1791993_-|hypothetical-protein
MKALEIDVTDIQERGIIAELPNNLVLELIYNTYDSFIYLSILNALNERITGYNKLVPNIDYLNLVRSDENLQLRCIKINEFSEEKDKITPQNLNKDYKFFLIGDDNETVETS
>NZ_CP024701.1|WP_099989560.1|1792615_1794367_-|hypothetical-protein
MSTGILKFSIDTYLNSKGFKDFKSNLKESMNLSQRFKSITGSALGQLAIGYFTISGLVGQYNKAIEASNYQIEQETKLYNTLRAQNFRDEQIKSIVDLTGSLQSLGVVGDEVTLAGAQQLATYRMQEDSIKKLLPTMQDLLVKQKGLNGTGQDMEGIASMFAKSMNGQTMALKRSGIILSEREEQLLKVGTEEEKVALLTNAVRRSIGEQNKEMLKTPEGKITSAKNRIGDLYETWGMSVRETRAKFWEFVADNAEGLKDVVNRVFKAGASFVDTFLGVFRDIKKGFNALPDSAKNAFKIIGAVAVATQFPLIALVLAIEDIFGAFQGKESFTEDAINALLKLTGTDYRFADLRKGVSDFFDLLIKGADSGIEKINLTTKVLSDLIDILKSGAGVLQMIWGATGGVAIDFTKNTYKAITGDFEGINWDNTTGNIKSGFNKVHNSAQNMSKTDDMHSAYLVDEANKKIQEQVKLENYINVNRGVKGVPLNGDYAVDLRNLTKTLSTFKDPKTLNTKTVQETKKMIKPEVTLTNTPTYNTNVTVNEATDGAKIQQMLDNSLRNKEKQDIEKLKAQLGVVNYGFGY
>NZ_CP024701.1|WP_099989561.1|1794513_1794939_-|hypothetical-protein
MEKKVININGYDVTVMEQPSSYVLKLEKEIGRTRIVDYTKEILKYPSGVNESLENIIGVPESIKYQDLELKLDDRGLYTMEKLFIAGLENVVFTGETFLKLLNKNIDDYKYQEIEKMGLEVWEQVKNIAFCGLVVDTFRRM
>NZ_CP024701.1|WP_099989562.1|1794978_1795392_-|hypothetical-protein
MANIYNYDSKNYELVIGKTRVDDYADDTKITIEYDGDFKSITKGVDGARSINQHNDYDAVIKFKILQNSPLNLSFKQLALTEGEKGTFPVTFVNKGLDGTMGAFSAKGFFKKIPTLEIGTDSKGVEWEVQCINLKMA
>NZ_CP024701.1|WP_099989563.1|1795402_1796389_-|hypothetical-protein
MGIILGAEKKIVFLNTHKPSPVDQATVNIIGVFSTKKAITEQLITSIKDVTGVVASDDVYKILQACFNGGAKQVLVFGKAVTGNNYKDLFDSVKNDWFGTVTDETDLEKIALISKEIGARQKMLFAQVKKDEDIMNSESKIKAIAEDTTALFFNKNEELTAGAVAGYAISKFAGSVLVANKLINGAVESGLIGAEQGVLDKNKANYVARMKGQLGLANGVTVTGDPIDMIHCLKALKFRLEEDLTLYLKATPKPTFADLSPIKSVILDRCNQFVKMKALVADKTVVEMIPLEEIPKNDILNGILAGVKITVYYAYGAKELDSDLYFSV
>NZ_CP024701.1|WP_099989564.1|1796388_1796898_-|hypothetical-protein
MNNLELEILFLDKIKELNNKFQVIPFEHLSKVNGQLKLPRVLARTISNNVIHKYTNDREDTEKYGVFKQTNINKHIISFSFTLSKKDSFIDVAIIRDYFTNVEAVNWWIKLNGLNLVIEEVGELKDITDYSASDLLERYVFDLTVRTSKELRTEIEIIKDVKFNIEGGN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

296251 : 358358

Fusobacterium_phage(80.43%)

terminase,protease,portal,tRNA,capsid,integrase,tail,plate,transposase,holin

attL 304413:304439|attR 348665:348691

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099988805.1\|296251_297496_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	2.2e-63	40.3
WP_099988806.1\|298537_299989_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_099988807.1\|300017_300803_+	hypothetical protein	NA	NA	NA	NA
WP_099988808.1\|300824_301607_+	hypothetical protein	NA	NA	NA	NA
WP_099988809.1\|301622_302228_+	hypothetical protein	NA	NA	NA	NA
WP_099988810.1\|302233_302851_+	hypothetical protein	NA	NA	NA	NA
WP_147383692.1\|303042_303585_+	translation initiation factor IF-3	A0A1L2CV30	Pectobacterium_phage	2.7e-10	36.5
WP_005893833.1\|303657_303864_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_099988811.1\|303899_304250_+	50S ribosomal protein L20	NA	NA	NA	NA
304413:304439	attL	NA	NA	NA	NA
WP_099988812.1\|304587_305805_-\|integrase	site-specific integrase	A0A0K2CZ62	Paenibacillus_phage	1.5e-27	30.3
WP_038370939.1\|305886_306099_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_099988813.1\|306108_306606_-	dUTP diphosphatase	A0A0E3U2S3	Fusobacterium_phage	3.0e-40	52.0
WP_099988814.1\|306628_306946_-	hypothetical protein	NA	NA	NA	NA
WP_005887751.1\|306949_307213_-	hypothetical protein	NA	NA	NA	NA
WP_038370936.1\|307216_307504_-	hypothetical protein	A0A0E3Y667	Fusobacterium_phage	6.9e-29	63.2
WP_099988815.1\|307513_307906_-	hypothetical protein	A0A0E3Y6C4	Fusobacterium_phage	1.6e-60	86.9
WP_099988816.1\|307902_308499_-	HNH endonuclease	A0A0E3T8L5	Staphylococcus_phage	8.7e-18	30.9
WP_005887743.1\|308500_308734_-	hypothetical protein	A0A2H4JB60	uncultured_Caudovirales_phage	2.4e-11	50.0
WP_099988817.1\|308756_309755_-	hypothetical protein	NA	NA	NA	NA
WP_099988818.1\|309756_310797_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	1.7e-24	27.2
WP_099988819.1\|310783_311518_-	N-6 DNA methylase	NA	NA	NA	NA
WP_099988820.1\|311514_312075_-	hypothetical protein	NA	NA	NA	NA
WP_099988821.1\|312076_312310_-	hypothetical protein	NA	NA	NA	NA
WP_099988822.1\|312306_312885_-	DNA repair protein Rad50	NA	NA	NA	NA
WP_099988823.1\|312884_313190_-	hypothetical protein	NA	NA	NA	NA
WP_029491756.1\|313198_313783_-	hypothetical protein	NA	NA	NA	NA
WP_099988824.1\|313845_314052_-	hypothetical protein	NA	NA	NA	NA
WP_099988825.1\|314164_314362_-	hypothetical protein	A0A0E3U2M4	Fusobacterium_phage	3.9e-07	54.5
WP_099988826.1\|314358_314976_-	hypothetical protein	A0A0E3U242	Fusobacterium_phage	1.3e-45	50.5
WP_099988827.1\|314965_315670_-	ParA family protein	A0A0E3Y677	Fusobacterium_phage	2.3e-81	61.7
WP_099988828.1\|315679_316072_-	hypothetical protein	NA	NA	NA	NA
WP_099988829.1\|316072_316303_-	hypothetical protein	A0A0E3Y5C9	Fusobacterium_phage	7.4e-18	66.2
WP_099988830.1\|316313_317426_-	hypothetical protein	A0A0S2SXI2	Bacillus_phage	1.4e-37	58.3
WP_099988831.1\|317435_318122_-	hypothetical protein	NA	NA	NA	NA
WP_147386411.1\|318207_318483_-	hypothetical protein	NA	NA	NA	NA
WP_099988833.1\|318632_318839_-	hypothetical protein	A0A0E3Y682	Fusobacterium_phage	4.9e-13	60.7
WP_099988834.1\|318940_319162_-	hypothetical protein	NA	NA	NA	NA
WP_099988835.1\|319456_319672_+	helix-turn-helix transcriptional regulator	Q331Y7	Clostridium_botulinum_C_phage	2.2e-08	41.8
WP_099988836.1\|319782_320328_+	DUF2321 domain-containing protein	NA	NA	NA	NA
WP_153232669.1\|320308_320458_-	hypothetical protein	NA	NA	NA	NA
WP_099988837.1\|320780_321512_+	hypothetical protein	NA	NA	NA	NA
WP_153232670.1\|321514_321673_-	hypothetical protein	NA	NA	NA	NA
WP_099988838.1\|321802_322006_-	hypothetical protein	NA	NA	NA	NA
WP_099988839.1\|322151_322598_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_099988840.1\|322621_323023_+	hypothetical protein	NA	NA	NA	NA
WP_099988841.1\|323078_323609_+	hypothetical protein	NA	NA	NA	NA
WP_099988842.1\|323610_323817_+	hypothetical protein	NA	NA	NA	NA
WP_099988843.1\|324028_324277_+	hypothetical protein	NA	NA	NA	NA
WP_008821176.1\|324243_324432_+	hypothetical protein	A0A0E3U2N2	Fusobacterium_phage	9.4e-11	53.2
WP_099988844.1\|324431_325517_+	hypothetical protein	A0A0E3U246	Fusobacterium_phage	4.9e-128	63.4
WP_099988845.1\|325740_326415_+	hypothetical protein	A0A0E3Y615	Fusobacterium_phage	3.1e-64	59.9
WP_099988846.1\|326528_327002_+	hypothetical protein	A0A0E3Y4U4	Fusobacterium_phage	1.0e-61	77.7
WP_099988847.1\|326940_328740_+\|terminase	phage terminase large subunit family protein	A0A0E3U2N4	Fusobacterium_phage	0.0e+00	91.3
WP_099987722.1\|328736_328955_+	hypothetical protein	A0A0E3U247	Fusobacterium_phage	2.8e-22	72.2
WP_099988848.1\|328963_330505_+\|portal	phage portal protein	A0A0E3Y693	Fusobacterium_phage	4.4e-279	94.7
WP_099988849.1\|330497_331607_+\|protease	Clp protease ClpP	A0A0E3Y6E9	Fusobacterium_phage	7.0e-170	86.2
WP_099988850.1\|331618_331936_+	hypothetical protein	A0A0E3Y5E3	Fusobacterium_phage	5.1e-49	94.3
WP_099988851.1\|331949_332957_+\|capsid	major capsid protein E	A0A0E3U2N5	Fusobacterium_phage	1.3e-175	91.0
WP_099988852.1\|333002_333227_+	hypothetical protein	A0A0E3U249	Fusobacterium_phage	1.4e-08	68.0
WP_099988853.1\|333238_333553_+	hypothetical protein	A0A0E3Y618	Fusobacterium_phage	1.9e-24	50.5
WP_099988854.1\|333552_334119_+	hypothetical protein	A0A0E3Y4U7	Fusobacterium_phage	3.0e-36	46.5
WP_099988855.1\|334118_334589_+	hypothetical protein	A0A0E3Y698	Fusobacterium_phage	9.8e-41	51.9
WP_099988856.1\|334590_334968_+	hypothetical protein	NA	NA	NA	NA
WP_099988857.1\|334957_336358_+\|tail	phage tail protein	A0A0E3U251	Fusobacterium_phage	3.4e-222	79.4
WP_099988858.1\|336367_336901_+\|tail	phage major tail tube protein	A0A0E3Y6F4	Fusobacterium_phage	9.3e-80	81.9
WP_099988859.1\|336909_337248_+	hypothetical protein	A0A0E3Y5E7	Fusobacterium_phage	5.8e-35	64.9
WP_099988860.1\|337421_337676_+	hypothetical protein	NA	NA	NA	NA
WP_099988861.1\|337746_340383_+\|tail	phage tail tape measure protein	A0A0E3U2N9	Fusobacterium_phage	6.4e-246	62.8
WP_099987737.1\|340372_340582_+	hypothetical protein	NA	NA	NA	NA
WP_099988862.1\|340583_341690_+	phage late control D family protein	A0A0E3U253	Fusobacterium_phage	7.8e-137	68.5
WP_099988863.1\|341682_342216_+\|plate	phage baseplate assembly protein V	A0A0E3Y4V1	Fusobacterium_phage	6.9e-67	69.5
WP_099988864.1\|342212_342599_+\|tail	phage tail protein	A0A0E3Y6A2	Fusobacterium_phage	8.1e-49	71.1
WP_099988865.1\|342598_342913_+	hypothetical protein	A0A0E3Y6F8	Fusobacterium_phage	7.5e-29	62.1
WP_099988866.1\|342905_344003_+\|plate	baseplate J/gp47 family protein	A0A0E3U2P1	Fusobacterium_phage	3.8e-160	75.7
WP_099988867.1\|343995_344631_+\|tail	phage tail protein I	A0A0E3U255	Fusobacterium_phage	6.3e-83	72.0
WP_147386412.1\|344627_345638_+	hypothetical protein	A0A0E3Y5F3	Fusobacterium_phage	1.4e-145	74.3
WP_099988868.1\|345634_345949_-	hypothetical protein	NA	NA	NA	NA
WP_099988869.1\|346048_346798_+	penicillin-binding protein	A0A0E3U2P7	Fusobacterium_phage	1.8e-52	45.8
WP_099988870.1\|346794_347337_+	N-acetylmuramoyl-L-alanine amidase	A0A0E3Y6A6	Fusobacterium_phage	7.9e-34	43.3
WP_008821147.1\|347346_347712_+	hypothetical protein	A0A0E3Y6G3	Fusobacterium_phage	1.2e-54	81.0
WP_099988871.1\|347708_347939_+	hypothetical protein	NA	NA	NA	NA
WP_099988872.1\|347950_348430_+\|holin	phage holin family protein	A0A0E3Y658	Fusobacterium_phage	6.1e-38	69.6
WP_099988873.1\|348877_349714_+	hypothetical protein	NA	NA	NA	NA
348665:348691	attR	NA	NA	NA	NA
WP_099988874.1\|349732_350554_+	hypothetical protein	NA	NA	NA	NA
WP_099985840.1\|350566_351538_+	porphobilinogen synthase	NA	NA	NA	NA
WP_099985841.1\|351636_352182_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_099972524.1\|352456_352864_+	YtxH domain-containing protein	NA	NA	NA	NA
WP_099988875.1\|352883_353375_+	hypothetical protein	NA	NA	NA	NA
WP_099972525.1\|353397_353649_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_099988876.1\|353836_355351_+	YfcC family protein	NA	NA	NA	NA
WP_099988877.1\|355481_355883_-	hypothetical protein	NA	NA	NA	NA
WP_099988878.1\|355956_357201_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	1.3e-63	40.6
WP_099989926.1\|357625_357778_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_147383690.1\|357902_358358_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA

DBSCAN-SWA_2

887936 : 894121

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005968315.1\|887936_888410_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	9.0e-26	49.0
WP_099989105.1\|888456_889170_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.2e-43	42.8
WP_099989106.1\|889578_890928_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	2.6e-49	31.1
WP_099989107.1\|890975_891995_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A127KMF9	Cyanophage	3.0e-66	44.7
WP_099989108.1\|891982_892567_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.7e-24	38.5
WP_099989109.1\|892606_894121_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.4e-58	42.9

DBSCAN-SWA_3

1779374 : 1821334

Fusobacterium_phage(85.71%)

terminase,tRNA,integrase,head,transposase,holin

attL 1784092:1784114|attR 1821335:1821357

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099971502.1\|1779374_1780796_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	5.4e-50	30.6
WP_099989548.1\|1780810_1781506_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_099958484.1\|1781481_1783818_-	endonuclease MutS2	F2Y0V3	Organic_Lake_phycodnavirus	2.5e-15	27.8
1784092:1784114	attL	NA	NA	NA	NA
WP_099989549.1\|1784179_1784563_+	hypothetical protein	NA	NA	NA	NA
WP_153232672.1\|1784587_1784761_+	hypothetical protein	NA	NA	NA	NA
WP_099989550.1\|1784788_1785271_-\|holin	phage holin family protein	A0A0E3Y658	Fusobacterium_phage	5.2e-29	53.9
WP_099989551.1\|1785271_1785631_-	DUF1353 domain-containing protein	A0A0E3Y4V5	Fusobacterium_phage	6.1e-59	89.9
WP_099989552.1\|1785642_1786143_-	M15 family metallopeptidase	A0A0E3Y6B0	Fusobacterium_phage	7.2e-90	95.2
WP_099989553.1\|1786334_1787081_-	penicillin-binding protein	A0A0E3U2P7	Fusobacterium_phage	5.1e-108	76.1
WP_099989554.1\|1787157_1787415_+	hypothetical protein	NA	NA	NA	NA
WP_099989555.1\|1788121_1788727_-	hypothetical protein	A0A0E3Y5G1	Fusobacterium_phage	3.1e-79	87.2
WP_099989556.1\|1788723_1789863_-	hypothetical protein	A0A0E3Y634	Fusobacterium_phage	1.9e-191	88.6
WP_099989557.1\|1789859_1790198_-	hypothetical protein	A0A0E3U2P9	Fusobacterium_phage	3.0e-47	84.8
WP_099989558.1\|1790207_1790819_-	hypothetical protein	A0A0E3U262	Fusobacterium_phage	4.5e-70	87.2
WP_099989967.1\|1790819_1791680_-	hypothetical protein	A0A0E3Y4V7	Fusobacterium_phage	1.3e-118	76.4
WP_099989559.1\|1791654_1791993_-	hypothetical protein	A0A0E3Y6B2	Fusobacterium_phage	1.4e-44	79.6
WP_099989560.1\|1792615_1794367_-	hypothetical protein	A0A0E3Y5G6	Fusobacterium_phage	6.4e-194	59.2
WP_099989561.1\|1794513_1794939_-	hypothetical protein	A0A0E3Y638	Fusobacterium_phage	3.8e-60	78.7
WP_099989562.1\|1794978_1795392_-	hypothetical protein	A0A0E3Y4V9	Fusobacterium_phage	1.4e-67	88.3
WP_099989563.1\|1795402_1796389_-	hypothetical protein	A0A0E3U2Q2	Fusobacterium_phage	1.3e-154	84.1
WP_099989564.1\|1796388_1796898_-	hypothetical protein	A0A0E3U264	Fusobacterium_phage	1.1e-82	89.3
WP_099989565.1\|1796890_1797226_-	hypothetical protein	A0A0E3Y6B6	Fusobacterium_phage	1.0e-47	82.0
WP_099989566.1\|1797228_1797717_-	hypothetical protein	A0A0E3Y6H6	Fusobacterium_phage	1.6e-65	74.1
WP_099989567.1\|1797703_1798123_-	hypothetical protein	A0A0E3Y5G9	Fusobacterium_phage	2.3e-57	81.3
WP_099989568.1\|1798166_1798994_-	hypothetical protein	A0A0E3U2Q5	Fusobacterium_phage	1.5e-132	83.3
WP_099989569.1\|1799007_1799622_-	hypothetical protein	A0A0E3U265	Fusobacterium_phage	4.0e-82	73.5
WP_099989570.1\|1799656_1800415_-\|head	phage head morphogenesis protein	A0A0E3Y641	Fusobacterium_phage	2.2e-127	88.1
WP_099989571.1\|1800418_1801927_-	hypothetical protein	A0A0E3Y4W1	Fusobacterium_phage	3.0e-248	85.9
WP_099989572.1\|1801928_1803209_-\|terminase	PBSX family phage terminase large subunit	A0A0E3Y6C0	Fusobacterium_phage	1.4e-214	85.9
WP_099989573.1\|1803198_1803654_-\|transposase	transposase	A0A0E3U2Q7	Fusobacterium_phage	4.2e-73	90.1
WP_147386462.1\|1803637_1805236_-	hypothetical protein	A0A2H4J2F5	uncultured_Caudovirales_phage	9.3e-99	43.7
WP_099989574.1\|1805598_1806132_+	hypothetical protein	NA	NA	NA	NA
WP_099989575.1\|1806311_1806674_-	RusA family crossover junction endodeoxyribonuclease	A0A0E3U267	Fusobacterium_phage	3.4e-33	60.2
WP_099989576.1\|1806678_1807182_-	hypothetical protein	A0A0E3Y4W5	Fusobacterium_phage	1.5e-26	41.3
WP_099989577.1\|1807191_1807941_-	oxidoreductase	A0A0C5AFE7	Paenibacillus_phage	1.5e-35	40.0
WP_099989578.1\|1807918_1808329_-	hypothetical protein	NA	NA	NA	NA
WP_099989579.1\|1808338_1809553_-	AAA family ATPase	A0A0E3Y6C3	Fusobacterium_phage	1.5e-170	76.7
WP_099989580.1\|1809553_1810282_-	helix-turn-helix domain-containing protein	A0A0E3Y6I4	Fusobacterium_phage	7.0e-94	91.7
WP_099989581.1\|1811310_1812171_-	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_099989582.1\|1812192_1812900_-	helix-turn-helix domain-containing protein	A0A0E3U270	Fusobacterium_phage	9.7e-117	89.4
WP_099989583.1\|1813090_1813372_+	hypothetical protein	NA	NA	NA	NA
WP_099989584.1\|1813405_1813594_+	hypothetical protein	NA	NA	NA	NA
WP_099989585.1\|1813595_1813865_+	hypothetical protein	NA	NA	NA	NA
WP_099989586.1\|1813861_1814299_+	hypothetical protein	NA	NA	NA	NA
WP_099989587.1\|1814561_1815155_+	ERF family protein	B6SBX8	Clostridium_virus	1.6e-40	55.8
WP_099989588.1\|1815167_1815677_+	hypothetical protein	A0A0E3U2R8	Fusobacterium_phage	2.0e-71	84.6
WP_099989589.1\|1815685_1816060_+	single-stranded DNA-binding protein	Q8SBL5	Clostridium_phage	1.2e-12	40.5
WP_099989590.1\|1816069_1816324_+	hypothetical protein	A0A0E3U272	Fusobacterium_phage	1.4e-30	81.9
WP_099989969.1\|1816471_1817053_+	hypothetical protein	A0A0E3Y6J2	Fusobacterium_phage	1.2e-99	90.7
WP_099989591.1\|1817123_1817726_+	hypothetical protein	A0A0E3U2M3	Fusobacterium_phage	9.4e-20	33.7
WP_099989592.1\|1817727_1817967_+	hypothetical protein	NA	NA	NA	NA
WP_147386463.1\|1817908_1818247_+	hypothetical protein	NA	NA	NA	NA
WP_099989594.1\|1818227_1818449_+	hypothetical protein	NA	NA	NA	NA
WP_147386464.1\|1818438_1818723_+	hypothetical protein	NA	NA	NA	NA
WP_099989596.1\|1818709_1819096_+	hypothetical protein	A0A0E3Y4X1	Fusobacterium_phage	1.7e-27	56.2
WP_099989597.1\|1819100_1819319_+	hypothetical protein	NA	NA	NA	NA
WP_099989598.1\|1819315_1819519_+	hypothetical protein	NA	NA	NA	NA
WP_099989970.1\|1819757_1820036_+	hypothetical protein	NA	NA	NA	NA
WP_099989599.1\|1820048_1820234_+	hypothetical protein	A0A0E3U274	Fusobacterium_phage	1.7e-20	80.3
WP_099989600.1\|1820302_1821334_+\|integrase	site-specific integrase	A0A0E3Y5J2	Fusobacterium_phage	1.1e-169	87.2
1821335:1821357	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage