CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	0 crisprs	csa3	0	0	0	0
NZ_CP024985	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 chromosome, complete genome	31 crisprs	cas5,cas8c,cas7b,WYL,csa3,cas3,DEDDh,DinG,casR,Cas9_archaeal,Cas14u_CAS-V,cas4	10	35	4	0

1. NZ_CP024985

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP024985_3

• CRISPR_ID: NZ_CP024985_3
• CRISPR_location: 59882-59991
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_3

Consensus_repeat	Method
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CRISPRCasFinder

spacers of NZ_CP024985_3

>3.1|59919|36|NZ_CP024985|CRISPRCasFinder
GTGCGAGGTCTACCCCGTCGTCTGTGGAGAACCGCA

CRISPR arrays and Neighbor proteins around NZ_CP024985_3

CRISPR arrays

The CRISPR arrays of NZ_CP024985_3

>merge|NZ_CP024985|3|59882-59991|CRISPRCasFinder
GTTGCGACCCTCGGCCGCCCCGAAGGACGACCGCCACGTGCGAGGTCTACCCCGTCGTCTGTGGAGAACCGCAGTTGCGATCCTCGGCCGTCCCGAACAGCGACCGCCAC

>NZ_CP024985|3|3|59882-59991|CRISPRCasFinder
GTTGCGACCCTCGGCCGCCCCGAAGGACGACCGCCAC	GTGCGAGGTCTACCCCGTCGTCTGTGGAGAACCGCA
GTTGCGATCCTCGGCCGTCCCGAACAGCGACCGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06

Protein sequences

>NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN
>NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART

Crispr_ID: NZ_CP024985_1

• CRISPR_ID: NZ_CP024985_1
• CRISPR_location: 58764-58876
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_1

Consensus_repeat	Method
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CRISPRCasFinder

spacers of NZ_CP024985_1

>1.1|58801|38|NZ_CP024985|CRISPRCasFinder
GTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCACGTC

CRISPR arrays and Neighbor proteins around NZ_CP024985_1

CRISPR arrays

The CRISPR arrays of NZ_CP024985_1

>merge|NZ_CP024985|1|58764-58876|CRISPRCasFinder
TTTGCGGTCCTCGGCCGTCCCGAAGGGCGACCGCCACGTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCACGTCGTTGCGATCCTCGGTCGTCCCGAAGGGCGACGGCCACC

>NZ_CP024985|1|1|58764-58876|CRISPRCasFinder
TTTGCGGTCCTCGGCCGTCCCGAAGGGCGACCGCCAC	GTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCACGTC
GTTGCGATCCTCGGTCGTCCCGAAGGGCGACGGCCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06

Protein sequences

>NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN
>NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART

Crispr_ID: NZ_CP024985_2

• CRISPR_ID: NZ_CP024985_2
• CRISPR_location: 58971-59671
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 9 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_2

Consensus_repeat	Method
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CRISPRCasFinder
GTTGCGATCCTCGGTCNNCCCGANGG	CRT
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	PILER-CR
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	PILER-CR

spacers of NZ_CP024985_2

>2.1|59008|34|NZ_CP024985|CRISPRCasFinder
ACCGACCACCCGCGGATTGCCACAGCCGCTCGCG
>2.2|59079|37|NZ_CP024985|CRISPRCasFinder
CTTCAGCCCGTCGCGCGGCGTGGTCGGGGCTCTTGGT
>2.3|59153|36|NZ_CP024985|CRISPRCasFinder,PILER-CR
GGTCGTCCTGGTTCTGCTCGTCGCCGGTCTCCTCTG
>2.4|59226|38|NZ_CP024985|CRISPRCasFinder,PILER-CR
CCGACGTCCGCCGGGCCCTCGAAAAGCACGTCATCGAG
>2.5|59301|37|NZ_CP024985|CRISPRCasFinder,PILER-CR
TCGGCAAGGGAGTCGACGTCACCGCCGCCACCAGGGA
>2.6|59375|36|NZ_CP024985|CRISPRCasFinder
GAAGGCGGGGACGATCAGCTTCTTCCACTTGAAGAG
>2.7|59448|38|NZ_CP024985|CRISPRCasFinder,PILER-CR
TCGCGCCGTCGCCAGGCACAGCAGGCCCTGAGCCTGGT
>2.8|59523|36|NZ_CP024985|CRISPRCasFinder,PILER-CR
GCTGCGCTCCCAGCACCGTCACCAGAAGCGGAGGCA
>2.9|59596|38|NZ_CP024985|CRISPRCasFinder,PILER-CR
CCGCGGCGAGGGCCGCGAACACCACGAACGACGAGGCC
>2.10|58997|45|NZ_CP024985|CRT
CAGCCGCCACCACCGACCACCCGCGGATTGCCACAGCCGCTCGCG
>2.11|59068|48|NZ_CP024985|CRT
GCGACCGCCACCTTCAGCCCGTCGCGCGGCGTGGTCGGGGCTCTTGGT
>2.12|59142|47|NZ_CP024985|CRT
ACGACCGCCACGGTCGTCCTGGTTCTGCTCGTCGCCGGTCTCCTCTG
>2.13|59215|49|NZ_CP024985|CRT
ACGACCGCCACCCGACGTCCGCCGGGCCCTCGAAAAGCACGTCATCGAG
>2.14|59290|48|NZ_CP024985|CRT
GCGACCGCCACTCGGCAAGGGAGTCGACGTCACCGCCGCCACCAGGGA
>2.15|59364|47|NZ_CP024985|CRT
GCGACCGCCACGAAGGCGGGGACGATCAGCTTCTTCCACTTGAAGAG
>2.16|59437|49|NZ_CP024985|CRT
GCGACCGCCACTCGCGCCGTCGCCAGGCACAGCAGGCCCTGAGCCTGGT
>2.17|59512|47|NZ_CP024985|CRT
GCGACCGCCACGCTGCGCTCCCAGCACCGTCACCAGAAGCGGAGGCA
>2.18|59585|49|NZ_CP024985|CRT
GCGACCGCCACCCGCGGCGAGGGCCGCGAACACCACGAACGACGAGGCC

CRISPR arrays and Neighbor proteins around NZ_CP024985_2

CRISPR arrays

The CRISPR arrays of NZ_CP024985_2

>merge|NZ_CP024985|2|58971-59671|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GTTGCGATCCTCGCTCGTCCCAAGGGCAGCCGCCACCACCGACCACCCGCGGATTGCCACAGCCGCTCGCGGTTGCGATCCTCGGTCGCCCCGAAGAGCGACCGCCACCTTCAGCCCGTCGCGCGGCGTGGTCGGGGCTCTTGGTGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACGGTCGTCCTGGTTCTGCTCGTCGCCGGTCTCCTCTGGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACCCGACGTCCGCCGGGCCCTCGAAAAGCACGTCATCGAGGTTGCGATCCTCGGTCGTTCCCAAGGGCGACCGCCACTCGGCAAGGGAGTCGACGTCACCGCCGCCACCAGGGAGTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCACGAAGGCGGGGACGATCAGCTTCTTCCACTTGAAGAGGTTGCAATCCTCGGTCCCCCCGAGGGGCGACCGCCACTCGCGCCGTCGCCAGGCACAGCAGGCCCTGAGCCTGGTGTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCACGCTGCGCTCCCAGCACCGTCACCAGAAGCGGAGGCAGTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCACCCGCGGCGAGGGCCGCGAACACCACGAACGACGAGGCCGTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCACG

>NZ_CP024985|2|2|58971-59671|CRISPRCasFinder
GTTGCGATCCTCGCTCGTCCCAAGGGCAGCCGCCACC	ACCGACCACCCGCGGATTGCCACAGCCGCTCGCG
GTTGCGATCCTCGGTCGCCCCGAAGAGCGACCGCCAC	CTTCAGCCCGTCGCGCGGCGTGGTCGGGGCTCTTGGT
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	GGTCGTCCTGGTTCTGCTCGTCGCCGGTCTCCTCTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CCGACGTCCGCCGGGCCCTCGAAAAGCACGTCATCGAG
GTTGCGATCCTCGGTCGTTCCCAAGGGCGACCGCCAC	TCGGCAAGGGAGTCGACGTCACCGCCGCCACCAGGGA
GTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCAC	GAAGGCGGGGACGATCAGCTTCTTCCACTTGAAGAG
GTTGCAATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	TCGCGCCGTCGCCAGGCACAGCAGGCCCTGAGCCTGGT
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	GCTGCGCTCCCAGCACCGTCACCAGAAGCGGAGGCA
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	CCGCGGCGAGGGCCGCGAACACCACGAACGACGAGGCC
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCACG

>NZ_CP024985|2|1|58971-59659|CRT
GTTGCGATCCTCGCTCGTCCCAAGGG	CAGCCGCCACCACCGACCACCCGCGGATTGCCACAGCCGCTCGCG
GTTGCGATCCTCGGTCGCCCCGAAGA	GCGACCGCCACCTTCAGCCCGTCGCGCGGCGTGGTCGGGGCTCTTGGT
GTTGCGATCCTCGGTCGTCCCGAAGG	ACGACCGCCACGGTCGTCCTGGTTCTGCTCGTCGCCGGTCTCCTCTG
GTTGCGATCCTCGGTCGTCCCGAAGG	ACGACCGCCACCCGACGTCCGCCGGGCCCTCGAAAAGCACGTCATCGAG
GTTGCGATCCTCGGTCGTTCCCAAGG	GCGACCGCCACTCGGCAAGGGAGTCGACGTCACCGCCGCCACCAGGGA
GTTGCGATCCTCGGTCGTCCCGAAGG	GCGACCGCCACGAAGGCGGGGACGATCAGCTTCTTCCACTTGAAGAG
GTTGCAATCCTCGGTCCCCCCGAGGG	GCGACCGCCACTCGCGCCGTCGCCAGGCACAGCAGGCCCTGAGCCTGGT
GTTGCGATCCTCGGTCCCCCCGAGGG	GCGACCGCCACGCTGCGCTCCCAGCACCGTCACCAGAAGCGGAGGCA
GTTGCGATCCTCGGTCCCCCCGAGGG	GCGACCGCCACCCGCGGCGAGGGCCGCGAACACCACGAACGACGAGGCC
GTTGCGATCCTCGGTCCCCCCGAGGG

>NZ_CP024985|2|1|59116-59374|PILER-CR
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	GGTCGTCCTGGTTCTGCTCGTCGCCGGTCTCCTCTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CCGACGTCCGCCGGGCCCTCGAAAAGCACGTCATCGAG
GTTGCGATCCTCGGTCGTTCCCAAGGGCGACCGCCAC	TCGGCAAGGGAGTCGACGTCACCGCCGCCACCAGGGA
GTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCACGAAGGCGGGGACGATCAGCTTCTTCCACTTGAAGAGGTTGCAATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	TCGCGCCGTCGCCAGGCACAGCAGGCCCTGAGCCTGGT
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	GCTGCGCTCCCAGCACCGTCACCAGAAGCGGAGGCA
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	CCGCGGCGAGGGCCGCGAACACCACGAACGACGAGGCC


>NZ_CP024985|2|2|59411-59670|PILER-CR
	GGTCGTCCTGGTTCTGCTCGTCGCCGGTCTCCTCTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CCGACGTCCGCCGGGCCCTCGAAAAGCACGTCATCGAG
GTTGCGATCCTCGGTCGTTCCCAAGGGCGACCGCCAC	TCGGCAAGGGAGTCGACGTCACCGCCGCCACCAGGGA
GTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCACGAAGGCGGGGACGATCAGCTTCTTCCACTTGAAGAGGTTGCAATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	TCGCGCCGTCGCCAGGCACAGCAGGCCCTGAGCCTGGT
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	GCTGCGCTCCCAGCACCGTCACCAGAAGCGGAGGCA
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC	CCGCGGCGAGGGCCGCGAACACCACGAACGACGAGGCC
GTTGCGATCCTCGGTCCCCCCGAGGGGCGACCGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06

Protein sequences

>NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN
>NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART

Crispr_ID: NZ_CP024985_4

• CRISPR_ID: NZ_CP024985_4
• CRISPR_location: 61149-62486
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 17 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_4

Consensus_repeat	Method
GTTGCGATCCTCGGTCATCCCGAAGGGC	CRISPRCasFinder
GTTGCGATCCTCGGTCNNCCCGAAGGGC	CRT
AGTTGCGATCCTCGGTCGTCCCAAAGGGCGACCGCCACG	PILER-CR
GTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCAC	PILER-CR
GTTGCGATCCTCGGTCATCCCGAAGGGC	CRISPRCasFinder

spacers of NZ_CP024985_4

>4.1|61177|45|NZ_CP024985|CRISPRCasFinder
AACCGCCATCCGCCACGGGGCCGCCCGCTGTACGTTCGGCCAGTC
>4.2|61250|47|NZ_CP024985|CRISPRCasFinder,CRT
GACCGCCACGCCGACGAGTCCGCCCACAAGCGCGCGACGGCCAAGTC
>4.3|61325|45|NZ_CP024985|CRISPRCasFinder,CRT
GGCCGCCACCAGCGGAACGCCACGCTTGCTGAACGTGTCCGCCTC
>4.4|61398|44|NZ_CP024985|CRISPRCasFinder,CRT
CACCGCCGCACCCCTGGCAGGGTCCGCGTGTCGTACTGCACATA
>4.5|61470|45|NZ_CP024985|CRISPRCasFinder,CRT
AACCGCCACGACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGGA
>4.6|61543|45|NZ_CP024985|CRISPRCasFinder,CRT
GACCGCCGCCACGGGTTCCGGTGAGACGATCGAGTACCCGGTGAA
>4.7|61616|45|NZ_CP024985|CRISPRCasFinder,CRT
GACCGCCACGCCCGCGCGCGGGTCCCGATCGAAGAGGACACCCTC
>4.8|61689|45|NZ_CP024985|CRISPRCasFinder,CRT
GACCGCCACGAGCTGGCCGGAGTCATTCTCAAGCCGGTCCGTGCG
>4.9|61762|44|NZ_CP024985|CRISPRCasFinder,CRT
AACCGCAACCCGGTGCGCTCGATCGGGCGGGTACAGCACCCGAC
>4.10|61834|43|NZ_CP024985|CRISPRCasFinder,CRT
GACCGCCACTCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGT
>4.11|61905|44|NZ_CP024985|CRISPRCasFinder,CRT
GACCACCACCAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGG
>4.12|61977|44|NZ_CP024985|CRISPRCasFinder,CRT
AACCGCCACCCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAG
>4.13|62049|45|NZ_CP024985|CRISPRCasFinder,CRT
GACCGCCACGTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTC
>4.14|62122|47|NZ_CP024985|CRT
GACCACCACGACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTT
>4.15|62197|46|NZ_CP024985|CRT
GCCGCCACCCCTTGCTGACGACGTACCGGGGCAACCCCATCGACTC
>4.16|62271|45|NZ_CP024985|CRT,CRISPRCasFinder
GACCGCCACGTCGTGCGTCCAGTACAGGCGCTTGTCCGTGCCGAG
>4.17|62344|43|NZ_CP024985|CRT,CRISPRCasFinder
ACCGCCATTCCGGCTCCGCGGAGCGATCTCCGCCCACCCCGAG
>4.18|62415|44|NZ_CP024985|CRT,CRISPRCasFinder
AACCGCCACCCGGTCCGGGCCGCCCGCTGTGCGTTCGGCCAGTC
>4.19|61480|34|NZ_CP024985|PILER-CR
ACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGG
>4.20|61553|37|NZ_CP024985|PILER-CR
GCCACGGGTTCCGGTGAGACGATCGAGTACCCGGTGA
>4.21|61629|34|NZ_CP024985|PILER-CR
CCCGCGCGCGGGTCCCGATCGAAGAGGACACCCT
>4.22|61843|34|NZ_CP024985|PILER-CR
TCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGT
>4.23|61914|35|NZ_CP024985|PILER-CR
CAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGG
>4.24|61986|35|NZ_CP024985|PILER-CR
CCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAG
>4.25|62058|36|NZ_CP024985|PILER-CR
GTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTC
>4.26|62131|38|NZ_CP024985|PILER-CR
GACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTT

CRISPR arrays and Neighbor proteins around NZ_CP024985_4

CRISPR arrays

The CRISPR arrays of NZ_CP024985_4

>merge|NZ_CP024985|4|61149-62486|CRISPRCasFinder,CRT,PILER-CR,PILER-CR,CRISPRCasFinder
GTTGCGATCCTCAGTCACCTTGAAGGGTAACCGCCATCCGCCACGGGGCCGCCCGCTGTACGTTCGGCCAGTCGTTGCGATCCACGGACGCCCCGCGGGGCGACCGCCACGCCGACGAGTCCGCCCACAAGCGCGCGACGGCCAAGTCGTTACGATCCTCAATCGCCCTGAAGGGCGGCCGCCACCAGCGGAACGCCACGCTTGCTGAACGTGTCCGCCTCGTTGCGATCCTCGGTCGCCCCGGAGGGCCACCGCCGCACCCCTGGCAGGGTCCGCGTGTCGTACTGCACATAGTTGCGATCCTCGGTCATCCCGAAGGGCAACCGCCACGACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGGAGTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCGCCACGGGTTCCGGTGAGACGATCGAGTACCCGGTGAAGTTGCGAACCTCGGTCGTCCCAAAGGACGACCGCCACGCCCGCGCGCGGGTCCCGATCGAAGAGGACACCCTCGTTGCGATCCTCGGTCGTCCCAAAGGGCGACCGCCACGAGCTGGCCGGAGTCATTCTCAAGCCGGTCCGTGCGGTTGCGATCCTCGGTCACCTCGAAAGGCAACCGCAACCCGGTGCGCTCGATCGGGCGGGTACAGCACCCGACGTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCACTCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGTGTTGCGATCCTCGGTCATCCCGAAGGGCGACCACCACCAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGGGTTGCGATCCTCGGTCATCCCGAAGGGCAACCGCCACCCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAGGTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCACGTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTCGTTGCGATCCTCGGTCGTCCCGAAGGACGACCACCACGACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTTGTTGCGATCCTCGTCGTCCCGAAGGGCGGCCGCCACCCCTTGCTGACGACGTACCGGGGCAACCCCATCGACTCGTTGCGATCCTCGGTCGTCCCGACGGACGACCGCCACGTCGTGCGTCCAGTACAGGCGCTTGTCCGTGCCGAGGTTGCGATCCTCGGTCACTCGAATGGCAACCGCCATTCCGGCTCCGCGGAGCGATCTCCGCCCACCCCGAGGTTGCGAACCTCGGTCACCCCGAAGGGCAACCGCCACCCGGTCCGGGCCGCCCGCTGTGCGTTCGGCCAGTCGTTGCGATCCTCGGTCGTCCCGAAGGGC

>NZ_CP024985|4|4|61149-62122|CRISPRCasFinder
GTTGCGATCCTCAGTCACCTTGAAGGGT	AACCGCCATCCGCCACGGGGCCGCCCGCTGTACGTTCGGCCAGTC
GTTGCGATCCACGGACGCCCCGCGGGGC	GACCGCCACGCCGACGAGTCCGCCCACAAGCGCGCGACGGCCAAGTC
GTTACGATCCTCAATCGCCCTGAAGGGC	GGCCGCCACCAGCGGAACGCCACGCTTGCTGAACGTGTCCGCCTC
GTTGCGATCCTCGGTCGCCCCGGAGGGC	CACCGCCGCACCCCTGGCAGGGTCCGCGTGTCGTACTGCACATA
GTTGCGATCCTCGGTCATCCCGAAGGGC	AACCGCCACGACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGGA
GTTGCGATCCTCGGTCGCCCCGAAGGGC	GACCGCCGCCACGGGTTCCGGTGAGACGATCGAGTACCCGGTGAA
GTTGCGAACCTCGGTCGTCCCAAAGGAC	GACCGCCACGCCCGCGCGCGGGTCCCGATCGAAGAGGACACCCTC
GTTGCGATCCTCGGTCGTCCCAAAGGGC	GACCGCCACGAGCTGGCCGGAGTCATTCTCAAGCCGGTCCGTGCG
GTTGCGATCCTCGGTCACCTCGAAAGGC	AACCGCAACCCGGTGCGCTCGATCGGGCGGGTACAGCACCCGAC
GTTGCGATCCTCGGTCGCCCCGAAGGGC	GACCGCCACTCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGT
GTTGCGATCCTCGGTCATCCCGAAGGGC	GACCACCACCAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGG
GTTGCGATCCTCGGTCATCCCGAAGGGC	AACCGCCACCCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGGC	GACCGCCACGTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCACCACGACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTTGTTGCGATCCTCGTCGTCCCGAAGGGCGGCCGCCACCCCTTGCTGACGACGTACCGGGGCAACCCCATCGACTCGTTGCGATCCTCGGTCGTCCCGACGGAC	GACCGCCACGTCGTGCGTCCAGTACAGGCGCTTGTCCGTGCCGAG
GTTGCGATCCTCGGTCACTCGAATGGCA	ACCGCCATTCCGGCTCCGCGGAGCGATCTCCGCCCACCCCGAG
GTTGCGAACCTCGGTCACCCCGAAGGGC	AACCGCCACCCGGTCCGGGCCGCCCGCTGTGCGTTCGGCCAGTC


>NZ_CP024985|4|2|61222-62486|CRT
GTTGCGATCCACGGACGCCCCGCGGGGC	GACCGCCACGCCGACGAGTCCGCCCACAAGCGCGCGACGGCCAAGTC
GTTACGATCCTCAATCGCCCTGAAGGGC	GGCCGCCACCAGCGGAACGCCACGCTTGCTGAACGTGTCCGCCTC
GTTGCGATCCTCGGTCGCCCCGGAGGGC	CACCGCCGCACCCCTGGCAGGGTCCGCGTGTCGTACTGCACATA
GTTGCGATCCTCGGTCATCCCGAAGGGC	AACCGCCACGACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGGA
GTTGCGATCCTCGGTCGCCCCGAAGGGC	GACCGCCGCCACGGGTTCCGGTGAGACGATCGAGTACCCGGTGAA
GTTGCGAACCTCGGTCGTCCCAAAGGAC	GACCGCCACGCCCGCGCGCGGGTCCCGATCGAAGAGGACACCCTC
GTTGCGATCCTCGGTCGTCCCAAAGGGC	GACCGCCACGAGCTGGCCGGAGTCATTCTCAAGCCGGTCCGTGCG
GTTGCGATCCTCGGTCACCTCGAAAGGC	AACCGCAACCCGGTGCGCTCGATCGGGCGGGTACAGCACCCGAC
GTTGCGATCCTCGGTCGCCCCGAAGGGC	GACCGCCACTCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGT
GTTGCGATCCTCGGTCATCCCGAAGGGC	GACCACCACCAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGG
GTTGCGATCCTCGGTCATCCCGAAGGGC	AACCGCCACCCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGGC	GACCGCCACGTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTC
GTTGCGATCCTCGGTCGTCCCGAAGGAC	GACCACCACGACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTT
GTTGCGATCCTCGTCGTCCCGAAGGGCG	GCCGCCACCCCTTGCTGACGACGTACCGGGGCAACCCCATCGACTC
GTTGCGATCCTCGGTCGTCCCGACGGAC	GACCGCCACGTCGTGCGTCCAGTACAGGCGCTTGTCCGTGCCGAG
GTTGCGATCCTCGGTCACTCGAATGGCA	ACCGCCATTCCGGCTCCGCGGAGCGATCTCCGCCCACCCCGAG
GTTGCGAACCTCGGTCACCCCGAAGGGC	AACCGCCACCCGGTCCGGGCCGCCCGCTGTGCGTTCGGCCAGTC
GTTGCGATCCTCGGTCGTCCCGAAGGGC

>NZ_CP024985|4|3|61441-61698|PILER-CR
AGTTGCGATCCTCGGTCATCCCGAAGGGCAACCGCCACG	ACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGG
AGTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCGCC	ACGGGTTCCGGTGAGACGATCGAGTACCCGGTGAAGT
TGCGAACCTCGGTCGTCCCAAAGGACGACCGCCACGCCC	GCGCGCGGGTCCCGATCGAAGAGGACACCCTCGT
TGCGATCCTCGGTCGTCCCAAAGGGCGACCGCCACGAGCTGGCCGGAGTCATTCTCAAGCCGGTCCGTGCGGTTGCGATCCTCGGTCACCTCGAAAGGCAACCGCAACCCGGTGCGCTCGATCGGGCGGGTACAGCACCCGACGTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCAC	TCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGT
GTTGCGATCCTCGGTCATCCCGAAGGGCGACCACCAC	CAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGG
GTTGCGATCCTCGGTCATCCCGAAGGGCAACCGCCAC	CCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCAC	GTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCACCAC	GACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTT


>NZ_CP024985|4|4|61806-62204|PILER-CR
	ACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGG
AGTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCGCC	ACGGGTTCCGGTGAGACGATCGAGTACCCGGTGAAGT
TGCGAACCTCGGTCGTCCCAAAGGACGACCGCCACGCCC	GCGCGCGGGTCCCGATCGAAGAGGACACCCTCGT
TGCGATCCTCGGTCGTCCCAAAGGGCGACCGCCACGAGCTGGCCGGAGTCATTCTCAAGCCGGTCCGTGCGGTTGCGATCCTCGGTCACCTCGAAAGGCAACCGCAACCCGGTGCGCTCGATCGGGCGGGTACAGCACCCGACGTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCAC	TCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGT
GTTGCGATCCTCGGTCATCCCGAAGGGCGACCACCAC	CAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGG
GTTGCGATCCTCGGTCATCCCGAAGGGCAACCGCCAC	CCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGGCGACCGCCAC	GTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCACCAC	GACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTT
GTTGCGATCCTCGTCGTCCCGAAGGGCGGCCGCCAC

>NZ_CP024985|4|5|62243-62486|CRISPRCasFinder
	AACCGCCATCCGCCACGGGGCCGCCCGCTGTACGTTCGGCCAGTC
GTTGCGATCCACGGACGCCCCGCGGGGC	GACCGCCACGCCGACGAGTCCGCCCACAAGCGCGCGACGGCCAAGTC
GTTACGATCCTCAATCGCCCTGAAGGGC	GGCCGCCACCAGCGGAACGCCACGCTTGCTGAACGTGTCCGCCTC
GTTGCGATCCTCGGTCGCCCCGGAGGGC	CACCGCCGCACCCCTGGCAGGGTCCGCGTGTCGTACTGCACATA
GTTGCGATCCTCGGTCATCCCGAAGGGC	AACCGCCACGACGCACGCACTCGTCGGCCGCGCGTGGGTGGAGGA
GTTGCGATCCTCGGTCGCCCCGAAGGGC	GACCGCCGCCACGGGTTCCGGTGAGACGATCGAGTACCCGGTGAA
GTTGCGAACCTCGGTCGTCCCAAAGGAC	GACCGCCACGCCCGCGCGCGGGTCCCGATCGAAGAGGACACCCTC
GTTGCGATCCTCGGTCGTCCCAAAGGGC	GACCGCCACGAGCTGGCCGGAGTCATTCTCAAGCCGGTCCGTGCG
GTTGCGATCCTCGGTCACCTCGAAAGGC	AACCGCAACCCGGTGCGCTCGATCGGGCGGGTACAGCACCCGAC
GTTGCGATCCTCGGTCGCCCCGAAGGGC	GACCGCCACTCGTGTTGGTAGTCTCCTCGTCCTCCCACTTGGT
GTTGCGATCCTCGGTCATCCCGAAGGGC	GACCACCACCAGCTTCCCCGGCGCCTGTCGCTTCCCACTGTGGG
GTTGCGATCCTCGGTCATCCCGAAGGGC	AACCGCCACCCGGACGGCCCCGGCAAGGTTGGCGCCGTTGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGGC	GACCGCCACGTCAGCTCCACAGGCTCGGGTGTCCCTAGGTCCGTC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCACCACGACCCGACAAGGGGGACCGTCAGCCGCGGGTGACGGTTGTTGCGATCCTCGTCGTCCCGAAGGGCGGCCGCCACCCCTTGCTGACGACGTACCGGGGCAACCCCATCGACTCGTTGCGATCCTCGGTCGTCCCGACGGAC	GACCGCCACGTCGTGCGTCCAGTACAGGCGCTTGTCCGTGCCGAG
GTTGCGATCCTCGGTCACTCGAATGGCA	ACCGCCATTCCGGCTCCGCGGAGCGATCTCCGCCCACCCCGAG
GTTGCGAACCTCGGTCACCCCGAAGGGC	AACCGCCACCCGGTCCGGGCCGCCCGCTGTGCGTTCGGCCAGTC
GTTGCGATCCTCGGTCGTCCCGAAGGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	9.19178e-87
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06

Protein sequences

>NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|48892_49327_-|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|48357_48774_+|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|44606_48008_+|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN
>NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase
MTTLAPQAVVRLGTRPSPMAMEQTGRFAQAFHACHPQLTLDIRKITSEGDAHRGPLSQIGGKGAFTRRADTHLLDGRVDATIACAKDLPGSHDRAPGTAVAAVLPREDVRDVLVLPVGHQPVTLAELPPGTRVGTSAPRRAALLASLFPQLVPVPIRGNADSRLDRLDHGRLGADVMIAALAGLRRLGFADRAGEVLDPTLWLPATGAGIIVVEHRADDTVTGGLLAPLTHPATRILLDAERAVLAELAGGCLTAASAHATLDDTGRVIVRAAVLDPAGGPSVRAEASGSTEHAAEIGRRTARALLNAGALRLLAVTHE

Crispr_ID: NZ_CP024985_5

• CRISPR_ID: NZ_CP024985_5
• CRISPR_location: 65102-65872
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 10 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_5

Consensus_repeat	Method
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CRISPRCasFinder
CCCGAAGGGCGACCGCC	PILER-CR

spacers of NZ_CP024985_5

>5.1|65139|38|NZ_CP024985|CRISPRCasFinder
CACCGCCCCTGCCAGGGCGGATCACCTTGGTTCCCGAA
>5.2|65214|35|NZ_CP024985|CRISPRCasFinder
CCGGCCCGCATCCGGCTGAGTGCGACGTGGAAGAG
>5.3|65286|33|NZ_CP024985|CRISPRCasFinder
CATCGTCGTACAGGTCCACCGCGCGCGCTCGAC
>5.4|65356|38|NZ_CP024985|CRISPRCasFinder
CCCAGCAGCCGACGCGGCTCGCGTACCGGGCCAGCCTG
>5.5|65431|36|NZ_CP024985|CRISPRCasFinder
CTGCTCGTCCAGGCCGAGAGCATCGGCAATCTGGTT
>5.6|65504|37|NZ_CP024985|CRISPRCasFinder
CCGCACTCCCCCACACGACAGGCCCCGCCGACACCCT
>5.7|65578|37|NZ_CP024985|CRISPRCasFinder
AGTAGTCCGTATCGATCGGGTTGTCCGTGTGCTGGTG
>5.8|65652|37|NZ_CP024985|CRISPRCasFinder
CCGCCGCGCGCTGTTGCTCTGCGGCCTGGTCGTGGTC
>5.9|65726|35|NZ_CP024985|CRISPRCasFinder
GCGGCGGACGGCCGGGGCTCCACCGGTCTGGTCTG
>5.10|65798|37|NZ_CP024985|CRISPRCasFinder
TCAACGGCATGGGCGCCGGAATCAGCACCGCCGTGCA
>5.11|65502|62|NZ_CP024985|PILER-CR
ACCCGCACTCCCCCACACGACAGGCCCCGCCGACACCCTGTTGCGATCCTCAGTCACCCCTG
>5.12|65581|57|NZ_CP024985|PILER-CR
ACAGTAGTCCGTATCGATCGGGTTGTCCGTGTGCTGGTGGTTGCGATCCTCAGTCAC
>5.13|65655|66|NZ_CP024985|PILER-CR
ACAACTTCCACCCGCCGCGCGCTGTTGCTCTGCGGCCTGGTCGTGGTCGTTGCGATCCTCGGTCGC
>5.14|65738|55|NZ_CP024985|PILER-CR
GCGCGGCGGACGGCCGGGGCTCCACCGGTCTGGTCTGGTTGCGATCCTTGGTCGT
>5.15|65810|57|NZ_CP024985|PILER-CR
ACTCAACGGCATGGGCGCCGGAATCAGCACCGCCGTGCAGTTGCGATCCTCGGTCGT

CRISPR arrays and Neighbor proteins around NZ_CP024985_5

CRISPR arrays

The CRISPR arrays of NZ_CP024985_5

>merge|NZ_CP024985|5|65102-65872|CRISPRCasFinder,PILER-CR
GTTGCGATCCTCGGTCATCCCAAAGGACGACCGCCACCACCGCCCCTGCCAGGGCGGATCACCTTGGTTCCCGAAGTTGCGATCCCCGGTCGTCCCGAGGGCGACCGCCACGCCGGCCCGCATCCGGCTGAGTGCGACGTGGAAGAGGTTGCGATCCTCGGCCGTTCCGAAGGGCGACCGCCACCATCGTCGTACAGGTCCACCGCGCGCGCTCGACGTTTCGTTCCTCAGTCGTGCGGGAGGACGACTACGACCCCAGCAGCCGACGCGGCTCGCGTACCGGGCCAGCCTGGCTGCGATCCACCGTCGCCCCGAAGGGCTACCACCACCTGCTCGTCCAGGCCGAGAGCATCGGCAATCTGGTTGTTGCGATCCTCGGTCGTCCCGAACGGCGACCGCCACCCGCACTCCCCCACACGACAGGCCCCGCCGACACCCTGTTGCGATCCTCAGTCACCCCTGAGGGCAACCGCCACAGTAGTCCGTATCGATCGGGTTGTCCGTGTGCTGGTGGTTGCGATCCTCAGTCACCCCGAAGGACAACTTCCACCCGCCGCGCGCTGTTGCTCTGCGGCCTGGTCGTGGTCGTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCGCGCGGCGGACGGCCGGGGCTCCACCGGTCTGGTCTGGTTGCGATCCTTGGTCGTCCCGAAGGGCGACCGCCACTCAACGGCATGGGCGCCGGAATCAGCACCGCCGTGCAGTTGCGATCCTCGGTCGTCCCGAAAGGCGACCGCCCCT

>NZ_CP024985|5|6|65102-65872|CRISPRCasFinder
GTTGCGATCCTCGGTCATCCCAAAGGACGACCGCCAC	CACCGCCCCTGCCAGGGCGGATCACCTTGGTTCCCGAA
GTTGCGATCCCCGGTCGTCCCGAGGGCGACCGCCACG	CCGGCCCGCATCCGGCTGAGTGCGACGTGGAAGAG
GTTGCGATCCTCGGCCGTTCCGAAGGGCGACCGCCAC	CATCGTCGTACAGGTCCACCGCGCGCGCTCGAC
GTTTCGTTCCTCAGTCGTGCGGGAGGACGACTACGAC	CCCAGCAGCCGACGCGGCTCGCGTACCGGGCCAGCCTG
GCTGCGATCCACCGTCGCCCCGAAGGGCTACCACCAC	CTGCTCGTCCAGGCCGAGAGCATCGGCAATCTGGTT
GTTGCGATCCTCGGTCGTCCCGAACGGCGACCGCCAC	CCGCACTCCCCCACACGACAGGCCCCGCCGACACCCT
GTTGCGATCCTCAGTCACCCCTGAGGGCAACCGCCAC	AGTAGTCCGTATCGATCGGGTTGTCCGTGTGCTGGTG
GTTGCGATCCTCAGTCACCCCGAAGGACAACTTCCAC	CCGCCGCGCGCTGTTGCTCTGCGGCCTGGTCGTGGTC
GTTGCGATCCTCGGTCGCCCCGAAGGGCGACCGCCGC	GCGGCGGACGGCCGGGGCTCCACCGGTCTGGTCTG
GTTGCGATCCTTGGTCGTCCCGAAGGGCGACCGCCAC	TCAACGGCATGGGCGCCGGAATCAGCACCGCCGTGCA
GTTGCGATCCTCGGTCGTCCCGAAAGGCGACCGCCCCT

>NZ_CP024985|5|5|65485-65869|PILER-CR
CCCGAACGGCGACCGCC	ACCCGCACTCCCCCACACGACAGGCCCCGCCGACACCCTGTTGCGATCCTCAGTCACCCCTG
AGGGCAACCGCCACAGT	AGTCCGTATCGATCGGGTTGTCCGTGTGCTGGTGGTTGCGATCCTCAGTCACCCCGA
AGGACAACTTCCACCCG	CCGCGCGCTGTTGCTCTGCGGCCTGGTCGTGGTCGTTGCGATCCTCGGTCGCCCCGAAGGGCGACC
GCCGCGCGGCGGACGGC	CGGGGCTCCACCGGTCTGGTCTGGTTGCGATCCTTGGTCGTCCCGAAGGGCGACC
GCCACTCAACGGCATGG	GCGCCGGAATCAGCACCGCCGTGCAGTTGCGATCCTCGGTCGTCCCGAAAGGCGACC
GCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239906.1|81458_81965_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239899.1|79111_79327_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP024985.1|WP_030239901.1|79414_80647_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_030239899.1|79111_79327_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.62772e-14
NZ_CP024985.1|WP_030239901.1|79414_80647_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.96529e-05
NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	9.19178e-87
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06

Protein sequences

>NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|49686_50448_+|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase
MTTLAPQAVVRLGTRPSPMAMEQTGRFAQAFHACHPQLTLDIRKITSEGDAHRGPLSQIGGKGAFTRRADTHLLDGRVDATIACAKDLPGSHDRAPGTAVAAVLPREDVRDVLVLPVGHQPVTLAELPPGTRVGTSAPRRAALLASLFPQLVPVPIRGNADSRLDRLDHGRLGADVMIAALAGLRRLGFADRAGEVLDPTLWLPATGAGIIVVEHRADDTVTGGLLAPLTHPATRILLDAERAVLAELAGGCLTAASAHATLDDTGRVIVRAAVLDPAGGPSVRAEASGSTEHAAEIGRRTARALLNAGALRLLAVTHE
>NZ_CP024985.1|WP_030239899.1|79111_79327_+|DUF397-domain-containing-protein
MGDAVPVGVAWQKSAACNGYEDCVEVARLANGNVGVRNSRLPDGPMVQFTSAELAAFLDGVGKGEFDWMTS
>NZ_CP024985.1|WP_030239901.1|79414_80647_+|helix-turn-helix-domain-containing-protein
MADRPSHPLARLVDPEGLDRHQSGTTLARRLWGLELREARDNLGWTGAEAVQRGAVSSTTVLSRLEQGKLRAKVTTSVAEALVRAYGVDEVTAVSWRSQAAAIENERSRPGGEVAVVDGDFSASPAFEDILRLERRASEIISFAGVFVPGRVQTRQYSRVVMERACDGRPELLVRVPERLRQRHQRQELLEWGTALHYSMIIDEHVLTTPIPGEAPMLEQLLELQKLARSREWIHLRVLPRSQWAHELPKAMTMSLFRFPAEQAESGEAAAPPAILYLEGSSPEVSRLYTDQARVDQHDANLNMLSNLSLDAEDSLGFIQEQVSRFEAKLRGGAAVRHGCTGAGLSRYAGHSPVLDPAGGGAGLGLGGMTRVPAGHVAGGVLSQHGEAGEEAGDVVAGTDVAPVPTQRVP
>NZ_CP024985.1|WP_030239906.1|81458_81965_-|hypothetical-protein
MITAFSGRVPHASPVLEACGTGAAARTGRKDVRAAEQTARTAFKARFDSAYRQYAAVRLGDDDAGDVVEAVWKQIELGWAGLLRCPSPAGGAWTLLSRAVHASPARPPSPLDKLPRPAADAFLLRHCVGLEADRAAEAMGMEPAAFESLYRSVVPRPGSGNPSGIFDR

Crispr_ID: NZ_CP024985_6

• CRISPR_ID: NZ_CP024985_6
• CRISPR_location: 65979-67624
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 25 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_6

Consensus_repeat	Method
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CRISPRCasFinder
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CRT
TTGCGATCCTCGGTCGNCCCGAAGGACGACCGCCAC	CRT
GTTGCGATCCTCGGTCGT	PILER-CR
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	PILER-CR

spacers of NZ_CP024985_6

>6.1|66016|35|NZ_CP024985|CRISPRCasFinder
CCGCACCGGGTCGCCCGCTGTACGTTCGGCCAGTC
>6.2|66088|36|NZ_CP024985|CRISPRCasFinder
CACAGCCATGGCGTCACCTCCGAATCTGTAACTCCG
>6.3|66161|36|NZ_CP024985|CRISPRCasFinder
ACCATCGTCGTACAGGTCCACCACGCGCGCTCGACA
>6.4|66234|36|NZ_CP024985|CRISPRCasFinder,CRT
CGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGC
>6.5|66307|36|NZ_CP024985|CRISPRCasFinder,CRT
GAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGC
>6.6|66380|36|NZ_CP024985|CRISPRCasFinder,CRT
CCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGT
>6.7|66453|38|NZ_CP024985|CRISPRCasFinder,CRT
CCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGT
>6.8|66528|37|NZ_CP024985|CRISPRCasFinder,CRT
GCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGG
>6.9|66602|36|NZ_CP024985|CRISPRCasFinder,CRT
CGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGA
>6.10|66675|36|NZ_CP024985|CRISPRCasFinder,CRT
CAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCC
>6.11|66748|34|NZ_CP024985|CRISPRCasFinder,CRT
GAATCTGATCATCACGGGGGGTCCCCGGTTCGGG
>6.12|66819|39|NZ_CP024985|CRISPRCasFinder,CRT
ACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAG
>6.13|66895|36|NZ_CP024985|CRISPRCasFinder,CRT
CTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTG
>6.14|66968|37|NZ_CP024985|CRISPRCasFinder,CRT
CCGCCCGGCGCTGCCCGCCCCTGCCCACGCGGAAGGT
>6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT
AGCACTTCGTCGGTGATCCGGGCCAGGGCCGCGGC
>6.16|67114|35|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
TCCCGTCCCTGATGGCGGCCGTGACCTGCTGGGTT
>6.17|67186|35|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
CGTGGCGGATGCTCCGGCGGACGTCTCGCAGTCAG
>6.18|67258|35|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
TTCGCGACCGGTGTCCTCGCCCACTTCGGCCTGTG
>6.19|67330|37|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
CGCCACCCTTCCCGTTCTGGCCCCGGGCGGGCTTGGG
>6.20|67404|37|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
ACCAGCACCCAGGACAGCTGCTCGATGCGGGTGCGCT
>6.21|67478|36|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
CACGTACGGCACGCACCAGGCCACGGCGCCGATGGC
>6.22|67551|37|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
CCGCCTCCGCCGACTCCTTCGCTGCCCAGAACGTCAG
>6.23|66234|37|NZ_CP024985|CRT
CGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGCG
>6.24|66307|37|NZ_CP024985|CRT
GAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGCG
>6.25|66380|37|NZ_CP024985|CRT
CCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGTG
>6.26|66453|39|NZ_CP024985|CRT
CCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGTG
>6.27|66528|38|NZ_CP024985|CRT
GCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGGG
>6.28|66602|37|NZ_CP024985|CRT
CGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGAC
>6.29|66509|56|NZ_CP024985|PILER-CR
CCTGAAGGGCAACCGCCAAGCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGG
>6.30|66583|59|NZ_CP024985|PILER-CR
CCCGAAGGACGACCGCCACCGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGACGTA
>6.31|66660|55|NZ_CP024985|PILER-CR
CCCGAAGGACAACCGCCACCAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCC
>6.32|66733|53|NZ_CP024985|PILER-CR
AGCGAGGGACCGCCACTCCGAATCTGATCATCACGGGGGGTCCCCGGTTCGGG
>6.33|66804|58|NZ_CP024985|PILER-CR
CCCAAAGGACGACCGCCACACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAG
>6.34|66880|55|NZ_CP024985|PILER-CR
CTCGAAGGGCGACCGCCACCTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTG

CRISPR arrays and Neighbor proteins around NZ_CP024985_6

CRISPR arrays

The CRISPR arrays of NZ_CP024985_6

>merge|NZ_CP024985|6|65979-67624|CRISPRCasFinder,CRT,CRT,PILER-CR,PILER-CR
GTTGCGAACCTCGGTCACCCCGAGGGGCAACCGCCACCCGCACCGGGTCGCCCGCTGTACGTTCGGCCAGTCGTTGCGATCCTCGATCGTCCCGAAGGACGACCGCCACCACAGCCATGGCGTCACCTCCGAATCTGTAACTCCGGTTGCGATCCTCGGTCGTCCCGAAGCAGACGACCGCCACCATCGTCGTACAGGTCCACCACGCGCGCTCGACATTTCGTTCCCTCAGTCGCGTGGGAGGACGACCGCCACCGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGCGTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCACGAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGCGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACCCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGTGTTGCGATTCTCGGTCGCCCCGAAGGGAGACCGCCACCCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGTGTTGCGATCCTCGGTCGTCCTGAAGGGCAACCGCCAAGCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGGGTTGCGATCCTCGATCGTCCCGAAGGACGACCGCCACCGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGACGTACGATCCTCGGTCGTCCCGAAGGACAACCGCCACCAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCCGTTGCGATCCTCGGTCGTAGCGAGGGACCGCCACTCCGAATCTGATCATCACGGGGGGTCCCCGGTTCGGGGTTGCGATCCTCGGTCGTCCCAAAGGACGACCGCCACACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAGGTTGCGATCCTCGGTCAGCTCGAAGGGCGACCGCCACCTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTGGTTGCGATCCTCGGTCGTCCCGAAGCGCGACCGCCACCCGCCCGGCGCTGCCCGCCCCTGCCCACGCGGAAGGTGTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCACAGCACTTCGTCGGTGATCCGGGCCAGGGCCGCGGCGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACTCCCGTCCCTGATGGCGGCCGTGACCTGCTGGGTTGTTGCGATCCTCGGTCGTCCCGAAAGACGACCGCCACCGTGGCGGATGCTCCGGCGGACGTCTCGCAGTCAGGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACTTCGCGACCGGTGTCCTCGCCCACTTCGGCCTGTGGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACCGCCACCCTTCCCGTTCTGGCCCCGGGCGGGCTTGGGGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACACCAGCACCCAGGACAGCTGCTCGATGCGGGTGCGCTGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCACCACGTACGGCACGCACCAGGCCACGGCGCCGATGGCGTTGCGATCCTCGGCCGTCCCGAAGGACGACCGCCACCCGCCTCCGCCGACTCCTTCGCTGCCCAGAACGTCAGGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC

>NZ_CP024985|6|7|65979-67624|CRISPRCasFinder
GTTGCGAACCTCGGTCACCCCGAGGGGCAACCGCCAC	CCGCACCGGGTCGCCCGCTGTACGTTCGGCCAGTC
GTTGCGATCCTCGATCGTCCCGAAGGACGACCGCCAC	CACAGCCATGGCGTCACCTCCGAATCTGTAACTCCG
GTTGCGATCCTCGGTCGTCCCGAAGCAGACGACCGCC	ACCATCGTCGTACAGGTCCACCACGCGCGCTCGACA
TTTCGTTCCCTCAGTCGCGTGGGAGGACGACCGCCAC	CGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGC
GTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCAC	GAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGT
GTTGCGATTCTCGGTCGCCCCGAAGGGAGACCGCCAC	CCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGT
GTTGCGATCCTCGGTCGTCCTGAAGGGCAACCGCCAA	GCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGG
GTTGCGATCCTCGATCGTCCCGAAGGACGACCGCCAC	CGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGA
CGTACGATCCTCGGTCGTCCCGAAGGACAACCGCCAC	CAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCC
GTTGCGATCCTCGGTCGTAGCGAGGGACCGCCACTCC	GAATCTGATCATCACGGGGGGTCCCCGGTTCGGG
GTTGCGATCCTCGGTCGTCCCAAAGGACGACCGCCAC	ACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAG
GTTGCGATCCTCGGTCAGCTCGAAGGGCGACCGCCAC	CTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTG
GTTGCGATCCTCGGTCGTCCCGAAGCGCGACCGCCAC	CCGCCCGGCGCTGCCCGCCCCTGCCCACGCGGAAGGT
GTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCAC	AGCACTTCGTCGGTGATCCGGGCCAGGGCCGCGGC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TCCCGTCCCTGATGGCGGCCGTGACCTGCTGGGTT
GTTGCGATCCTCGGTCGTCCCGAAAGACGACCGCCAC	CGTGGCGGATGCTCCGGCGGACGTCTCGCAGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TTCGCGACCGGTGTCCTCGCCCACTTCGGCCTGTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CGCCACCCTTCCCGTTCTGGCCCCGGGCGGGCTTGGG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	ACCAGCACCCAGGACAGCTGCTCGATGCGGGTGCGCT
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CACGTACGGCACGCACCAGGCCACGGCGCCGATGGC
GTTGCGATCCTCGGCCGTCCCGAAGGACGACCGCCAC	CCGCCTCCGCCGACTCCTTCGCTGCCCAGAACGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC

>NZ_CP024985|6|4|66197-67624|CRT
TTTCGTTCCCTCAGTCGCGTGGGAGGACGACCGCCAC	CGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGC
	CGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGCG
TTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCAC	GAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGC
	GAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGCG
TTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGT
	CCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGTG
TTGCGATTCTCGGTCGCCCCGAAGGGAGACCGCCAC	CCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGT
	CCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGTG
TTGCGATCCTCGGTCGTCCTGAAGGGCAACCGCCAA	GCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGG
	GCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGGG
TTGCGATCCTCGATCGTCCCGAAGGACGACCGCCAC	CGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGA
	CGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGAC
GTACGATCCTCGGTCGTCCCGAAGGACAACCGCCAC	CAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCC
GTTGCGATCCTCGGTCGTAGCGAGGGACCGCCACTCC	GAATCTGATCATCACGGGGGGTCCCCGGTTCGGG
GTTGCGATCCTCGGTCGTCCCAAAGGACGACCGCCAC	ACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAG
GTTGCGATCCTCGGTCAGCTCGAAGGGCGACCGCCAC	CTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTG
GTTGCGATCCTCGGTCGTCCCGAAGCGCGACCGCCAC	CCGCCCGGCGCTGCCCGCCCCTGCCCACGCGGAAGGT
GTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCAC	AGCACTTCGTCGGTGATCCGGGCCAGGGCCGCGGC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TCCCGTCCCTGATGGCGGCCGTGACCTGCTGGGTT
GTTGCGATCCTCGGTCGTCCCGAAAGACGACCGCCAC	CGTGGCGGATGCTCCGGCGGACGTCTCGCAGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TTCGCGACCGGTGTCCTCGCCCACTTCGGCCTGTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CGCCACCCTTCCCGTTCTGGCCCCGGGCGGGCTTGGG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	ACCAGCACCCAGGACAGCTGCTCGATGCGGGTGCGCT
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CACGTACGGCACGCACCAGGCCACGGCGCCGATGGC
GTTGCGATCCTCGGCCGTCCCGAAGGACGACCGCCAC	CCGCCTCCGCCGACTCCTTCGCTGCCCAGAACGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC

>NZ_CP024985|6|3|66198-66674|CRT
TTCGTTCCCTCAGTCGCGTGGGAGGACGACCGCCAC	CGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGC
	CGTCGGCGAACTCGCCTTCCGGATCGCGGAGTACGCG
TTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCAC	GAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGC
	GAGGGCTCGGCGCACTCGGCTGTCGAGCGTTCCGGCG
TTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGT
	CCCGACTCCGCCCACTTCCGCCAGACGGAGGAGCGTG
TTGCGATTCTCGGTCGCCCCGAAGGGAGACCGCCAC	CCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGT
	CCCGGCGTGCCGGCCGACGTGCCTGTCGTGCCGCTGGTG
TTGCGATCCTCGGTCGTCCTGAAGGGCAACCGCCAA	GCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGG
	GCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGGG
TTGCGATCCTCGATCGTCCCGAAGGACGACCGCCAC	CGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGA
	CGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGAC
GTACGATCCTCGGTCGTCCCGAAGGACAACCGCCAC	CAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCC
GTTGCGATCCTCGGTCGTAGCGAGGGACCGCCACTCC	GAATCTGATCATCACGGGGGGTCCCCGGTTCGGG
GTTGCGATCCTCGGTCGTCCCAAAGGACGACCGCCAC	ACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAG
GTTGCGATCCTCGGTCAGCTCGAAGGGCGACCGCCAC	CTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTG
GTTGCGATCCTCGGTCGTCCCGAAGCGCGACCGCCAC	CCGCCCGGCGCTGCCCGCCCCTGCCCACGCGGAAGGT
GTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCAC	AGCACTTCGTCGGTGATCCGGGCCAGGGCCGCGGC
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TCCCGTCCCTGATGGCGGCCGTGACCTGCTGGGTT
GTTGCGATCCTCGGTCGTCCCGAAAGACGACCGCCAC	CGTGGCGGATGCTCCGGCGGACGTCTCGCAGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TTCGCGACCGGTGTCCTCGCCCACTTCGGCCTGTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CGCCACCCTTCCCGTTCTGGCCCCGGGCGGGCTTGGG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	ACCAGCACCCAGGACAGCTGCTCGATGCGGGTGCGCT
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CACGTACGGCACGCACCAGGCCACGGCGCCGATGGC
GTTGCGATCCTCGGCCGTCCCGAAGGACGACCGCCAC	CCGCCTCCGCCGACTCCTTCGCTGCCCAGAACGTCAG


>NZ_CP024985|6|6|66491-66948|PILER-CR
GTTGCGATCCTCGGTCGT	CCTGAAGGGCAACCGCCAAGCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGG
GTTGCGATCCTCGATCGT	CCCGAAGGACGACCGCCACCGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGACGTA
CGATCCTCGGTCGTCCCG	AAGGACAACCGCCACCAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCCGTTG
CGATCCTCGGTCGTAGCG	AGGGACCGCCACTCCGAATCTGATCATCACGGGGGGTCCCCGGTTCGGGGTTG
CGATCCTCGGTCGTCCCA	AAGGACGACCGCCACACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAGGTTG
CGATCCTCGGTCAGCTCG	AAGGGCGACCGCCACCTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTGGTTG
CGATCCTCGGTCGTCCCGAAGCGCGACCGCCACCCGCCCGGCGCTGCCCGCCCCTGCCCACGCGGAAGGTGTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCACAGCACTTCGTCGGTGATCCGGGCCAGGGCCGCGGCGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TCCCGTCCCTGATGGCGGCCGTGACCTGCTGGGTT
GTTGCGATCCTCGGTCGTCCCGAAAGACGACCGCCAC	CGTGGCGGATGCTCCGGCGGACGTCTCGCAGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TTCGCGACCGGTGTCCTCGCCCACTTCGGCCTGTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CGCCACCCTTCCCGTTCTGGCCCCGGGCGGGCTTGGG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	ACCAGCACCCAGGACAGCTGCTCGATGCGGGTGCGCT
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CACGTACGGCACGCACCAGGCCACGGCGCCGATGGC
GTTGCGATCCTCGGCCGTCCCGAAGGACGACCGCCAC	CCGCCTCCGCCGACTCCTTCGCTGCCCAGAACGTCAG


>NZ_CP024985|6|7|67077-67624|PILER-CR
	CCTGAAGGGCAACCGCCAAGCCCGCGCCGCCGAGCTGTACGACGAGCAGGAAGCGG
GTTGCGATCCTCGATCGT	CCCGAAGGACGACCGCCACCGGACCAGTCGAGACCGAGGAGCGAGGCGATTCCGACGTA
CGATCCTCGGTCGTCCCG	AAGGACAACCGCCACCAGCCCGCGCTTCTTCATCTCCTTCACGAGCGCGCCGTTG
CGATCCTCGGTCGTAGCG	AGGGACCGCCACTCCGAATCTGATCATCACGGGGGGTCCCCGGTTCGGGGTTG
CGATCCTCGGTCGTCCCA	AAGGACGACCGCCACACCGATGCCGTAGAGCTCCCCGACCAGCCGGTGGTGCAGGTTG
CGATCCTCGGTCAGCTCG	AAGGGCGACCGCCACCTCCAGGCCAGGCGTCGCGAGGCTGATGCCGCGCTGGTTG
CGATCCTCGGTCGTCCCGAAGCGCGACCGCCACCCGCCCGGCGCTGCCCGCCCCTGCCCACGCGGAAGGTGTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCACAGCACTTCGTCGGTGATCCGGGCCAGGGCCGCGGCGTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TCCCGTCCCTGATGGCGGCCGTGACCTGCTGGGTT
GTTGCGATCCTCGGTCGTCCCGAAAGACGACCGCCAC	CGTGGCGGATGCTCCGGCGGACGTCTCGCAGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	TTCGCGACCGGTGTCCTCGCCCACTTCGGCCTGTG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CGCCACCCTTCCCGTTCTGGCCCCGGGCGGGCTTGGG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	ACCAGCACCCAGGACAGCTGCTCGATGCGGGTGCGCT
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	CACGTACGGCACGCACCAGGCCACGGCGCCGATGGC
GTTGCGATCCTCGGCCGTCCCGAAGGACGACCGCCAC	CCGCCTCCGCCGACTCCTTCGCTGCCCAGAACGTCAG
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239899.1|79111_79327_+|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP024985.1|WP_030239901.1|79414_80647_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239906.1|81458_81965_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_030239899.1|79111_79327_+|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.62772e-14
NZ_CP024985.1|WP_030239901.1|79414_80647_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.96529e-05
NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	9.19178e-87
NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06

Protein sequences

>NZ_CP024985.1|WP_158740930.1|65628_65943_-|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_100660728.1|62987_64244_-|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_030239879.1|62639_63038_+|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_159038045.1|61306_61459_-|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239875.1|56938_57280_+|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|54589_55213_+|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|54217_54571_+|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|52969_53674_+|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|52659_52878_+|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|51732_52248_+|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_078950658.1|67812_70086_+|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|70526_71219_+|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|71223_72993_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|73058_73955_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|74052_74469_+|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|74783_75332_+|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239897.1|75352_76312_+|hydroxymethylbilane-synthase
MTTLAPQAVVRLGTRPSPMAMEQTGRFAQAFHACHPQLTLDIRKITSEGDAHRGPLSQIGGKGAFTRRADTHLLDGRVDATIACAKDLPGSHDRAPGTAVAAVLPREDVRDVLVLPVGHQPVTLAELPPGTRVGTSAPRRAALLASLFPQLVPVPIRGNADSRLDRLDHGRLGADVMIAALAGLRRLGFADRAGEVLDPTLWLPATGAGIIVVEHRADDTVTGGLLAPLTHPATRILLDAERAVLAELAGGCLTAASAHATLDDTGRVIVRAAVLDPAGGPSVRAEASGSTEHAAEIGRRTARALLNAGALRLLAVTHE
>NZ_CP024985.1|WP_030239899.1|79111_79327_+|DUF397-domain-containing-protein
MGDAVPVGVAWQKSAACNGYEDCVEVARLANGNVGVRNSRLPDGPMVQFTSAELAAFLDGVGKGEFDWMTS
>NZ_CP024985.1|WP_030239901.1|79414_80647_+|helix-turn-helix-domain-containing-protein
MADRPSHPLARLVDPEGLDRHQSGTTLARRLWGLELREARDNLGWTGAEAVQRGAVSSTTVLSRLEQGKLRAKVTTSVAEALVRAYGVDEVTAVSWRSQAAAIENERSRPGGEVAVVDGDFSASPAFEDILRLERRASEIISFAGVFVPGRVQTRQYSRVVMERACDGRPELLVRVPERLRQRHQRQELLEWGTALHYSMIIDEHVLTTPIPGEAPMLEQLLELQKLARSREWIHLRVLPRSQWAHELPKAMTMSLFRFPAEQAESGEAAAPPAILYLEGSSPEVSRLYTDQARVDQHDANLNMLSNLSLDAEDSLGFIQEQVSRFEAKLRGGAAVRHGCTGAGLSRYAGHSPVLDPAGGGAGLGLGGMTRVPAGHVAGGVLSQHGEAGEEAGDVVAGTDVAPVPTQRVP
>NZ_CP024985.1|WP_030239906.1|81458_81965_-|hypothetical-protein
MITAFSGRVPHASPVLEACGTGAAARTGRKDVRAAEQTARTAFKARFDSAYRQYAAVRLGDDDAGDVVEAVWKQIELGWAGLLRCPSPAGGAWTLLSRAVHASPARPPSPLDKLPRPAADAFLLRHCVGLEADRAAEAMGMEPAAFESLYRSVVPRPGSGNPSGIFDR

Crispr_ID: NZ_CP024985_7

• CRISPR_ID: NZ_CP024985_7
• CRISPR_location: 990799-990917
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP024985_7

Consensus_repeat	Method
TCCGCGTCGGCCTCGCCCTCGCC	CRISPRCasFinder

spacers of NZ_CP024985_7

>7.1|990822|19|NZ_CP024985|CRISPRCasFinder
CCCCGACGCGAACGCGGGG
>7.2|990864|31|NZ_CP024985|CRISPRCasFinder
CTCGCCCTCCGCTTCGGCGTCTCCCTCGCCT

CRISPR arrays and Neighbor proteins around NZ_CP024985_7

CRISPR arrays

The CRISPR arrays of NZ_CP024985_7

>merge|NZ_CP024985|7|990799-990917|CRISPRCasFinder
TCCCCGCTGGCCGCGCTGTCGGCCCCCGACGCGAACGCGGGGGCACCCTCCGCGTCGGCCTCGCCCTCGCCCTCCGCTTCGGCGTCTCCCTCGCCTTCGGCGTCCGCTTCCGCTTCGGC

>NZ_CP024985|7|8|990799-990917|CRISPRCasFinder
TCCCCGCTGGCCGCGCTGTCGGC	CCCCGACGCGAACGCGGGG
GCACCCTCCGCGTCGGCCTCGCC	CTCGCCCTCCGCTTCGGCGTCTCCCTCGCCT
TCGGCGTCCGCTTCCGCTTCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_037687226.1|996913_997618_-|response-regulator	unknown	unknown	gnl|CDD|226931
NZ_CP024985.1|WP_030229771.1|1003161_1004571_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|224423
NZ_CP024985.1|WP_078950313.1|999743_1001105_+|cation:dicarboxylase-symporter-family-transporter	unknown	unknown	gnl|CDD|234968
NZ_CP024985.1|WP_030229778.1|994030_995422_-|glutamate-decarboxylase	unknown	unknown	gnl|CDD|130848
NZ_CP024985.1|WP_030229790.1|978618_979602_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238568
NZ_CP024985.1|WP_030229770.1|1004654_1005323_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|378676
NZ_CP024985.1|WP_158740641.1|988752_989580_+|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NZ_CP024985.1|WP_030229777.1|995721_996114_+|tyrosinase	unknown	unknown	gnl|CDD|368807
NZ_CP024985.1|WP_051840843.1|988004_988640_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl|CDD|188632
NZ_CP024985.1|WP_030229788.1|980979_982635_+|GMC-family-oxidoreductase	unknown	unknown	gnl|CDD|225186
NZ_CP024985.1|WP_158740643.1|980231_980375_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037687229.1|987015_988002_-|hypothetical-protein	unknown	unknown	gnl|CDD|238571
NZ_CP024985.1|WP_030229769.1|1005434_1006673_-|MFS-transporter	unknown	unknown	gnl|CDD|340887
NZ_CP024985.1|WP_030229784.1|985850_987050_+|hypothetical-protein	unknown	unknown	gnl|CDD|381056
NZ_CP024985.1|WP_030229787.1|982693_983173_-|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|225039
NZ_CP024985.1|WP_030229772.1|1001395_1003165_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173799
NZ_CP024985.1|WP_030229785.1|984418_985747_+|glycoside-hydrolase-family-18-protein	unknown	unknown	gnl|CDD|119365
NZ_CP024985.1|WP_030229786.1|983169_984249_-|dihydrodipicolinate-reductase	unknown	unknown	gnl|CDD|226326
NZ_CP024985.1|WP_030229776.1|996110_996959_+|tyrosinase-family-protein	unknown	unknown	gnl|CDD|365987
NZ_CP024985.1|WP_030229779.1|991545_994020_+|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl|CDD|227226

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_037687226.1|996913_997618_-|response-regulator	gnl|CDD|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	2.07015e-63
NZ_CP024985.1|WP_030229771.1|1003161_1004571_-|alpha/beta-fold-hydrolase	gnl|CDD|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	8.38552e-06
NZ_CP024985.1|WP_030229772.1|1001395_1003165_+|S8-family-serine-peptidase	gnl|CDD|173799	cd07473, Peptidases_S8_Subtilisin_like, Peptidase S8 family domain in Subtilisin-like proteins. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	3.22588e-50
NZ_CP024985.1|WP_078950313.1|999743_1001105_+|cation:dicarboxylase-symporter-family-transporter	gnl|CDD|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	1.73952e-157
NZ_CP024985.1|WP_030229790.1|978618_979602_-|ABC-transporter-substrate-binding-protein	gnl|CDD|238568	cd01148, TroA_a, Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	3.83242e-103
NZ_CP024985.1|WP_030229770.1|1004654_1005323_-|(2Fe-2S)-binding-protein	gnl|CDD|378676	pfam11575, FhuF_C, FhuF 2Fe-2S C-terminal domain. This family consists of several bacterial ferric iron reductase protein (FhuF) sequences. FhuF is involved in the reduction of ferric iron in cytoplasmic ferrioxamine B. This domain is the C-terminal domain that contains 4 conserved cysteine residues that are found to be part of a 2Fe-2S cluster.	5.57526e-09
NZ_CP024985.1|WP_158740641.1|988752_989580_+|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.98686e-60
NZ_CP024985.1|WP_030229777.1|995721_996114_+|tyrosinase	gnl|CDD|368807	pfam06236, MelC1, Tyrosinase co-factor MelC1. This family consists of several tyrosinase co-factor MELC1 proteins from a number of Streptomyces species. The melanin operon (melC) of Streptomyces antibioticus contains two genes, melC1 and melC2 (apotyrosinase). It is thought that MelC1 forms a transient binary complex with the downstream apotyrosinase MelC2 to facilitate the incorporation of copper ion and the secretion of tyrosinase indicating that MelC1 is a chaperone for the apotyrosinase MelC2.	1.20732e-27
NZ_CP024985.1|WP_030229786.1|983169_984249_-|dihydrodipicolinate-reductase	gnl|CDD|226326	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown].	6.12614e-60
NZ_CP024985.1|WP_030229788.1|980979_982635_+|GMC-family-oxidoreductase	gnl|CDD|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	2.99359e-11
NZ_CP024985.1|WP_037687229.1|987015_988002_-|hypothetical-protein	gnl|CDD|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	2.10052e-54
NZ_CP024985.1|WP_030229769.1|1005434_1006673_-|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.5513e-30
NZ_CP024985.1|WP_030229784.1|985850_987050_+|hypothetical-protein	gnl|CDD|381056	cd19590, serpin_thermopin-like, serpin thermopin and similar proteins. Thermopin, the serpin from Thermobifida fusca, functions as an irreversible proteinase inhibitor with resistance to polymerization at high temperatures. The crystal structure of the cleaved thermopin was found to adopt the canonical serpin fold, supporting its inclusion as a classical inhibitory member of the serpin superfamily. A detailed structural comparison revealed unique features, including charge-stabilizing interactions, a deleted element of secondary structure (the G helix), and a C-terminal "tail" that interacts with the top of the A beta sheet and plays an important role in the folding/unfolding of the molecule. These unique features provide structural and biophysical evidence as to how this unusual serpin member has adapted to remain functional in an extreme environment. SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate blood coagulation cascades. Non-inhibitory serpins perform many diverse functions such as chaperoning proteins or transporting hormones. Serpins are of medical interest because mutants have been associated with blood clotting disorders, emphysema, cirrhosis, and dementia. A classification based on evolutionary relatedness has resulted in the assignment of serpins to 16 clades designated A-P along with some orphans.	2.28286e-11
NZ_CP024985.1|WP_030229787.1|982693_983173_-|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	2.82856e-12
NZ_CP024985.1|WP_051840843.1|988004_988640_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl|CDD|188632	cd00452, KDPG_aldolase, KDPG and KHG aldolase. KDPG and KHG aldolase. This family belongs to the class I adolases whose reaction mechanism involves Schiff base formation between a substrate carbonyl and lysine residue in the active site. 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase, is best known for its role in the Entner-Doudoroff pathway of bacteria, where it catalyzes the reversible cleavage of KDPG to pyruvate and glyceraldehyde-3-phosphate. 2-keto-4-hydroxyglutarate (KHG) aldolase, which has enzymatic specificity toward glyoxylate, forming KHG in the presence of pyruvate, and is capable of regulating glyoxylate levels in the glyoxylate bypass, an alternate pathway when bacteria are grown on acetate carbon sources.	1.72332e-43
NZ_CP024985.1|WP_030229785.1|984418_985747_+|glycoside-hydrolase-family-18-protein	gnl|CDD|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	1.39907e-120
NZ_CP024985.1|WP_030229778.1|994030_995422_-|glutamate-decarboxylase	gnl|CDD|130848	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha., glutamate decarboxylase. This model represents the pyridoxal phosphate-dependent glutamate (alpha) decarboxylase found in bacteria (low and hi-GC gram positive, proteobacteria and cyanobacteria), plants, fungi and at least one archaon (Methanosarcina). The product of the enzyme is gamma-aminobutyrate (GABA).	0
NZ_CP024985.1|WP_030229776.1|996110_996959_+|tyrosinase-family-protein	gnl|CDD|365987	pfam00264, Tyrosinase, Common central domain of tyrosinase. This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.	3.48142e-46
NZ_CP024985.1|WP_030229779.1|991545_994020_+|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|227226	COG4889, COG4889, Predicted helicase [General function prediction only].	4.98475e-57

Protein sequences

>NZ_CP024985.1|WP_158740641.1|988752_989580_+|IclR-family-transcriptional-regulator
MSTEQVPGRGSEDVTGAAAEAPGPVRAGRTSAAGSALEKSLRILEAVAAPGGPHRLTDVMTAAAVPKSSTFRILAALAEQGFVRAEGDGRYGTGPRLHGLSALVRAAEPAGVDEVLRELRRETGQTVHLALHTGETITYVRKLEADQPFRTASRVGTRMPLHTTAIGKSVLALLPPEEVRALVASAGLPRRTPRTLTTAAELEAELAAVRARGFAVDDEENEPSIRCAGVAVPGPDGRPLGGVSVTTVTFLVSRQEAEGYAPALRAAAKALAPLL
>NZ_CP024985.1|WP_051840843.1|988004_988640_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MAAQRLLPVLRNTGADEAVRAATDLLAAGCRAVELTTSTPGWASAVARTAALTDARGRRALIGVGTVTTGAQAEEALDAGAGFLVSPYPAPAVREVARRRAAVFVEGGFTPGEIATAARSAGAAKVFPAHVGGPDFLRSLKAVLPDALLIPTGGIRPDEVRTWLAAGAGAVGIGSGLPAEPARLAALFAELAGPCCEACGEDPGGPGGGVR
>NZ_CP024985.1|WP_037687229.1|987015_988002_-|hypothetical-protein
MAAASRPYDVLVLGEVLVEIQAGTALRATADGTDARISFSGDALNAAAAAAAAGARTALLAVVGDDELGGPLLRRAAELGIDVSHVHRAPRPNGAYLVGADTEGEREFVYWRTRSAGSTLSPAHTGAWRELLSGAGALITSGITGALSPSAREAVLDAARTVHAAGGHLTYDPNHRPRLTGRDGARELLARIAPMTGLLKTSCPADAVALVDTADPRAAAARYRALGARAVAVTCGSGRLLLDDGARVARFPVPPNPAPIDATGAGDCFTGTATARIVLGDTLARAVAHGVAAASLSVSGRGGTGCVPAFADTAALAATVRPGTEPGP
>NZ_CP024985.1|WP_030229784.1|985850_987050_+|hypothetical-protein
MRNSTVRAVNRLTERWAAAAPAAEAATVFTAAGLWPLLALLADGAGGPARTELAEALGIPAGDAARAARELLAGLGAVRGLRSATGLWTREDLALEPGWSAGLPPGTRGTLSGDPDRDREALDGWTRERTDGEIERMPVALPEGPDRVRLLLASALALRLRWIQPFREGYGEPHEGPWTGRPLRVLRRDTTLLDRVGVARGPGGAVTLLEVVGDAGVDVHLVLGEPRATPGEVLTTGIGAVTHALPATGVSLLPNGAPGPGLRVGTAVCASPEPRLFIETAAFEVRAEHDLLERAGVFGLETASDSGRGHFPGIGPEPLAVGSARQAAVARFHALGFEAAAVTAIAAAPGSAAPGRRYRTRGAKVAFDRPFGFLAVHRTSRLVLAAGWITDPVPYPDGP
>NZ_CP024985.1|WP_030229785.1|984418_985747_+|glycoside-hydrolase-family-18-protein
MRRSMLGRLAVAACSLSLLTAFAPAAGSSPQNGEGRHDRALRRVGYFTQWGFYGRDFQVRDLETSGAAGRLTHIDYAFGNVGADGRCFTGNVPGEADAWADYVRPLDAADSVDGVADTAEQPLAGNFNQLRELKAKHPGLKVMISLGGWSWSPHFSDAALTPASRTAFVRSCIDLYIKGNLPQDGSRGGAGAAAGLFDGIDLDWEWPGSAGDTDTTYRPEDRRNFAALVEEFRRQLDAYGRERRRGYELSAFVPTAPAKIDAGFDVRRIMRGLDFVNLQGYDFHVSGEKTTAQQSALRARDDFSVEGTVEAWRRRGAPAGKLVVGMPFYGQGWTGVGGGGDGMGQPATGPAPATWAAGYEDYKELKKLAASGTYRVYRDRRGGHAWLFDGSTLWTYDDPQVLNAKARHVREQGLGGAMFWSLDGDTADAELTAAVDRGLRGR
>NZ_CP024985.1|WP_030229786.1|983169_984249_-|dihydrodipicolinate-reductase
MIPTVVWGTGNVGRAAIRAVEAHPALVLTAVIVHNPGKVGRDAGELAGLDRRLGVAATDDATAVLAARPAAVVYAASGDVRPDDALTDITRAIAAGAVVVSPALYPLYDHRGAPPEFRDPVLAAVAEGGGSLFASGVDPGWGNDVLPLLLSGLGSTVDAIRCQEIFDYSTYDQPDSVRHLVGMGQPMDQEPMMLMPSVPTTVWGGQVRMMARALGVELDEIRETSERRALDATVTTRTMGEFEAGTQGAIRFEVQGIVEGEPRIVIEHVTRIHPSCAPDWPTPPDGSGAHRVVIEGRPRIEVTVECTDEDDNRSAGGNATAVGRLVGAIDWLVEAEPGLYDALDVPLRPAVGKLGRKQP
>NZ_CP024985.1|WP_030229787.1|982693_983173_-|carboxymuconolactone-decarboxylase-family-protein
MRIDVPEGQHPIEYVWGDLVPGIGMAAANFSLSVYAHTTLGLREFEAARLRIAQINGCVFCLDWRTDRDGEKVEEGFADAVTEWRTTGAFDDRTRLAAEYAERYALDHHNLDEEFWARMTAHYSQVEIVELSMSIGSWLAFGRLNHVLGLDSVCVLPGG
>NZ_CP024985.1|WP_030229788.1|980979_982635_+|GMC-family-oxidoreductase
MSDKSLHSKVSKGVSRRGFMAGTGSILGALALAVNTVPARAEGVTGAAVASAPIDSGAHVPALVIGTGYGGSVAALRLAQAGVDVHMIEMGMAWDTPGSDGKIFANTTKPDYRSYWLRTRTKAPLSNFLGFPIDKDVPRYTGILDAEEMGGIIVYQGRGVGGGSLVNGGMAVTPKRQNFAAILPSVDAEEMYSTYYPRANAGLGVGLVDPDWFETVDCYQFARVGRKHAQRSGFPFVFVPDVYDWDYMKQEVAGTVPKSAVDGEILYGNNAGKKSLQKTYIAAARATGRVAISPLHRVTTVSPSAGGGYTVGMEQLDTTGAVVATKTVTADRVFFAAGSVGTSKLLVRLKATGALADLNDEIGKGWGDNGNVMCGRANHMWDPTGKVQASIPCGGIDNWDAGGAFAEVAPLPTGIETYASFYLSITKNPNRAEFTWNAAAGKVDLNWQTAWKQPSIDMAKTIFDKINAKEGTIYRTDLFGTNKIWGDHLTYHPLGGAVLNRATDNYGRLRGYTGLYVIDGALIPGNTSVNPFVTITALAERNIEKIIATDL
>NZ_CP024985.1|WP_158740643.1|980231_980375_-|hypothetical-protein
MIPTPAEDRAAELNERIRALVAVGQAGSDEYQALLREWLRATLVPAA
>NZ_CP024985.1|WP_030229790.1|978618_979602_-|ABC-transporter-substrate-binding-protein
MSRSRAALRSIAALAALVPLAACGGPADGPAGAVPPAPGFPYTVTNCGVTSTYQAPPERAVTMNQHATEIMLALGLQDRMVGTAYLDDSVLPAYRPAYDKIKVLAGEYPSKEVLLGADPDFVYGGYASAFDKGQGRDREGLARSGIGSRLSVEYCTRGPVGLAQLKTEITEVARTFGVPERGAALVEDEQRRVDTVTARLKDRPKPPVFVYDSGEGSAFTSGGNGIGNEIVSLAGGTNVFADLDDTFGDVSWEKVIERKPEVVLIYDYGGTTVESKKQRLLNDPALAEVPAVKNRRFVVLPLSSAVLGVRVADAVESLGRQLHPDAA
>NZ_CP024985.1|WP_030229779.1|991545_994020_+|DEAD/DEAH-box-helicase-family-protein
MAKPQLRAHQREAVDAVVRALEPPADGRLPGRGLRTQVIMATGSGKSLVAVRSAEELRAGRVLVLVPSLDLLVQTVSAWRAGGRTGRALAVCSLRGEDAGLPTTTDPGRLARWGAGPVERMTVFATYASLGQGTVERAHLAGLPPWDLIVVDEAHRTSGRIGKPWAVVHDNARIPSARRLYMTATPRVWRDGEEPEAEGAEGEYGEEGPRARGAGGPRGRGELVASMEDDPEGPFGARCYTLSLSEAIDRGICAPYRVVCVDVSDPGFRSAVLLGADGRSDRVRGIRLAALQAALVKAAADQGFRRTLVFHHLTKEAEAFAAGLPAVAARMRAASRSALPAYPRTVWADWLCGQHTAAHRRRVLEAFAADRVAEKAFLGSVRVLGEGVDTKECDSVFWADVRGSMPDLVQAVGRALRIRPGEGKVASLVVPVLLAPGESPETMLTSRAYGDLARLLEALRAHDSRLVEALAQPQAPGRPASAAGAAGSTGGPGPGAAALLSFSTPRDPALLAAFIRLRVLNPEHTRWRRGAEAARIYAATAGDLRVPFAYRVPESGGQWPPALAGFPLGQWVADARRTYRRGALGRERMRELDELGMVWSHFDVAFEEGLAAARAWAAEHGHLLPPVDATWHGAPVGVWMKNNRAAARREGPGALPEERREALDRIDPSWCPVWDIGWQRAFHLTRTHLDAGGQVPPVPGRVLVQGEDLGAWVRAQRLGWERLAWSQRWLLEHALGLAPAPEAERPPPRRSHASAWSGYLEAARRFHAREGHLVVPRPHVERWGDQELRLGVWIANQRSRAAKLPPERAAALTALGMRWSRTGG
>NZ_CP024985.1|WP_030229778.1|994030_995422_-|glutamate-decarboxylase
MALHETKDARARDADTDVFTSALSGQILPKYRMPEDHSPSEVVYSLLHNELLLDGNAAQNLATFCTTWSDDGVHRLMNECLDKNMIDKDEYPQTAEIEARCVNILADLWNAPKGTSGTGCSTTGSSEAAMLGGLALKWRWRARRRAEGKPADRPNLVCGPVQICWEKFARYFDVELRQVPLEPGATGLVPHQLAAHVDENTIGVVAILGVTYTCDYEPVAEIAAELDRIQEEHGWDIPVHVDAASGGFVAPFLHPDVVWDFRLPRVASVNTSGHKYGLAPLGVGWIVWRTAELLPADLVFDVDYLGGDMPTFALNFSRPGGEVIAQYYLFLRLGRGGYRRVQQACADTAQYLAGEIAGMGPFTLLYDGQGGLPAVSYTLADPAGAGFTLYDLSDRLRMRGWQVPTYPLPADRQDTVMQRVLIRHGVTRDQIALLVSDLRAAVEHLAAHPQPVPATEPRSGFHH
>NZ_CP024985.1|WP_030229777.1|995721_996114_+|tyrosinase
MNKITRRQALGTTAGALTVLGIAGATAHAAATDSRAATTPAGTVDEVYQGRRIQIAPGTGGGHHGGHHSPGLPTVKIDGRELHVMQNADGTWISVVNHYETFADPTSLARAAVRELQGSQLAPMQMGGMA
>NZ_CP024985.1|WP_030229776.1|996110_996959_+|tyrosinase-family-protein
MTVRKNQAALTPEEKRAFTNALLELKRTGRYDRFVTTHNGFIMSDTDSGDRVGHRSPSFLPWHRRFLLEFEAALQAVDASVSIPYWDWTADRTTRSSLWAADFLGGTGRARDGQVMDGPFAYATGKWEVAVRVDGRNYLRRALGEGVAQLPTKAEVDAVLAMPVYDMAPWNSSSNGFRNNLEGWRGANLHNRVHVWVGGQMATGVSPNDPVFWMHHAFIDKLWADWQAKHPTSTYLPAAGTANVVDLRDTMRPWNDVTPADMLDHRKFYTFDTEPAAAASQR
>NZ_CP024985.1|WP_037687226.1|996913_997618_-|response-regulator
MSAPEVRVLVVEDDPVAAAAHALYVGRVPGFTAVAAVHSLAEATRVLERTQVDLLLLDLTLPDGHGLRFARGLRAAGHPVDVIAVTSARDLAVVRESVSLGVVQYVLKPFAFPTLRERLLRYAEFRASAGEAAGQDDVDRALAALRAPGPAELPKGLSAPTLDRVAALLRAAPDGLTAAGAAEAAGISRITARRYLEHLVDTGRADRTPRYGQVGRPELHYRWLAAAAGSVSNV
>NZ_CP024985.1|WP_078950313.1|999743_1001105_+|cation:dicarboxylase-symporter-family-transporter
MIAAVLLGITVGFAAPGVAVELKPLGTGFVNLIKMMISPVIFCTIVLGIGSVRKAAKVGAVGGLALGYFMVMSTVALAIGLVVGNLLEPGSGLHLTEAVRHAGEAQAKAGGAESTPEFLLGIIPTTLVSAFTGGEVLQTLLVALLCGFALQAMGTAGEPVLRGIGHVQKLVFRVLAMIMWAAPVGAFGAIAAVVGATGVDALKSLAVIMIGFYTTCLLFVIVVLGTLLRVCTGVSIFALLRYLGREFLLILSTSSSESALPRLIAKMEHLGVSRPVTGITVPTGYSFNLDGTAIYLTMSSLFVAEAMGKPLALGEQISLLLFMIVASKGAAGVTGAGLATLAGGLQSHRPELVDGVGLIVGIDRFMSEARALTNFAGNAVATVLIGTWTKEFDRERATEVLAGRLPFDETTLIDDGHGTHPDGAPAAVPAPSADSSATPSAGPSAGAEDGVPV
>NZ_CP024985.1|WP_030229772.1|1001395_1003165_+|S8-family-serine-peptidase
MMAAALGAALAFGAPAAIAGTAPVNPNGSAPASAPAAAPKAAAPASQSATWAAGTRAYLVISAPGDSTAIRSAVTANGGTVFSSFDAIGVIVAHSTSATFASTMRGVSGVQQVGATRTSDVPADAYNPALPANPAQSSTAAGEPVRADMSQIKADQAWAVTTGSPSVKVGILDTGVDDQHQDLAPNFNAADSVSCAYGKPDTRTGAWRDVDTHGTHVAGTVAAAKNGKGVVGVAPGVKISAVRVAEPGNSFFFAENTICGFVWAGDHGFKVTNNSYYTDPWQFNCPDNIDQAAIIEGVKRAQEYAESKGSLQIAAAGNEDYDLAHKTTDTASPNDSTPVTRTITNACMDIPTELPGVVTVAANGTGVTKASFSNFGQGVIDVAAPGQDVYSTLPGGKYGTKSGTSMATPHVVGVAALIASANPGITPAQIRDKLATQANDIACPADGRCTGTTANNSFFGEGQVDALKAVGATPPAGKYFENTADFAIGDNTTVESPITVSGVTGNAPATLKVGVNIVHTYIGDLKVDLVAPDGSVYTVHNRAGGSTDNINQVFTVNASSEVANGTWKLRVNDNAGGDTGRIDSWNLTF
>NZ_CP024985.1|WP_030229771.1|1003161_1004571_-|alpha/beta-fold-hydrolase
MNAPTSRPPGGVSRRTALTGLAAGAGSLALPGTGTAHAAPAAPSPSATAAEPAPGAMELFADPGFNFAGLLALGAAGMRASEVGEVLTAVNAVNAAGLSEQSYTDTFRAWGDRLAAPPAGGRHGGDVPPQTGRFRSLRAAQYYAQALFYVLGTTSPADEKAVYLAGRAAWDAFTRLCSPAVVRAKVPYGGTHLPVWFFRPDGPARRRPTVILTNGSDGQNVDMWTYGVSAALDRGWNALVYDGPGQGQLLFVEEIPFTTRWEEVVAPLVDWLVPRGDVDAARIALTGLSMGGNLVARAAAFEHRLAAVVCEPGCVSPWLGFDKELRDIVTPDKAQTNRVWNEEVLPELPPQLAFTVKKRFEIFDRQALRQARAGKVLTDLWTPAQVAIGLDITKLVARIKAPTLVLDYDFEQFYPGQPRQMYDLLRSPREYVKMTEATGAQLHCSPMAPQQHCDVVFDWLDGTLRPDRS
>NZ_CP024985.1|WP_030229770.1|1004654_1005323_-|(2Fe-2S)-binding-protein
MDDVLRRLAAVGPFFTVAHGERPPGPGFRPLGELYGEHLAPYVAEVGRRIGSGPGRVAASTAQFGIASRLWSLGLGCAALGGPVPDLDPARLWWRLPPAGSLELWLPEPAARPAGDLGEIVLGNLAVLDAALRERYGVSAKVLRGNAASGLVGALRVLLDRVPGEPAVEPAGALLADGGPLAGTGTFVHEEGLGVAFVRRSCCLYYRVPGGGLCGDCVLRTR
>NZ_CP024985.1|WP_030229769.1|1005434_1006673_-|MFS-transporter
MTIRFLPAPGAPRRLAAAQLSNSVGDGAYYVCSALYFTRVVGLSPAQIGLGLTLAWAIGSVAGVPLGALADRRGPRGTSVLLALATAASVASFLFIRSFGAFLCAVVLYAVSQCGLAAARQALLAGLVAPGERTGVLAHLQSTLNAGLALGAALGGLALGAGTERAYLVVLALDALSFLGCAALLATLPAVPPVPDRAPGAPRLAVLRDRPYALVTLLNAVLLLRMPLLSLAIPLWIVERTQAPGWLVSALFVLNTVAVMLFQVRVARPVTDLDSATRALRVSGLVMALSCAVFAASALPGAGWAAAALLVAGAALQADGEMRQSAGSWQIGFSLAPAEHMGQYQGFFGTGVPVARTLGPLLLTSLLLLWGIPGWLLLGALLLAASYAMGPAVRRARSAARAEGASAEGVSA

Crispr_ID: NZ_CP024985_8

• CRISPR_ID: NZ_CP024985_8
• CRISPR_location: 1027871-1027961
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_8

Consensus_repeat	Method
CGGCGACACCGTCAACATGTACGGCGGCCGGG	CRISPRCasFinder

spacers of NZ_CP024985_8

>8.1|1027903|27|NZ_CP024985|CRISPRCasFinder
GCAACTCGGGGGTGACCCACGGATGAG

CRISPR arrays and Neighbor proteins around NZ_CP024985_8

CRISPR arrays

The CRISPR arrays of NZ_CP024985_8

>merge|NZ_CP024985|8|1027871-1027961|CRISPRCasFinder
CGGCGACACCGTCAACATGTACGGCGGCCGGGGCAACTCGGGGGTGACCCACGGATGAGCGGCGACACCGTGAACATGTACGGCGGCCGGG

>NZ_CP024985|8|9|1027871-1027961|CRISPRCasFinder
CGGCGACACCGTCAACATGTACGGCGGCCGGG	GCAACTCGGGGGTGACCCACGGATGAG
CGGCGACACCGTGAACATGTACGGCGGCCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_167456818.1|1034578_1035295_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP024985.1|WP_030229740.1|1032722_1033328_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP024985.1|WP_100660780.1|1035294_1036290_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP024985.1|WP_051840835.1|1028317_1029439_-|S-(hydroxymethyl)mycothiol-dehydrogenase	unknown	unknown	gnl|CDD|132492
NZ_CP024985.1|WP_030229753.1|1020064_1021255_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NZ_CP024985.1|WP_030229735.1|1037350_1039048_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP024985.1|WP_030229747.1|1026350_1027115_-|PIG-L-family-deacetylase	unknown	unknown	gnl|CDD|225031
NZ_CP024985.1|WP_030229750.1|1023723_1024623_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187627
NZ_CP024985.1|WP_030229741.1|1031894_1032698_+|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl|CDD|381605
NZ_CP024985.1|WP_030229743.1|1029476_1030451_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_CP024985.1|WP_030229756.1|1017923_1018124_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229755.1|1018138_1018912_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740639.1|1022535_1023669_+|hypothetical-protein	unknown	unknown	gnl|CDD|379369
NZ_CP024985.1|WP_030229736.1|1036376_1037276_-|squalene/phytoene-synthase-family-protein	unknown	unknown	gnl|CDD|366130
NZ_CP024985.1|WP_030229748.1|1025455_1026292_-|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|223955
NZ_CP024985.1|WP_030229749.1|1024668_1025469_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229752.1|1021251_1022244_-|NADPH:quinone-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|176203
NZ_CP024985.1|WP_051840833.1|1030521_1031442_+|dihydrodipicolinate-synthase	unknown	unknown	gnl|CDD|188637
NZ_CP024985.1|WP_100661246.1|1033324_1034557_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP024985.1|WP_030229754.1|1018949_1020068_-|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|224871

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_167456818.1|1034578_1035295_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	9.74923e-09
NZ_CP024985.1|WP_030229740.1|1032722_1033328_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	9.81122e-61
NZ_CP024985.1|WP_100660780.1|1035294_1036290_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.53274e-83
NZ_CP024985.1|WP_051840835.1|1028317_1029439_-|S-(hydroxymethyl)mycothiol-dehydrogenase	gnl|CDD|132492	TIGR03451, S-hydroxymethylmycothiol_dehydrogenase, S-(hydroxymethyl)mycothiol dehydrogenase. Members of this protein family are mycothiol-dependent formaldehyde dehydrogenase (EC 1.2.1.66). This protein is found, so far, only in the Actinobacteria (Mycobacterium sp., Streptomyces sp., Corynebacterium sp., and related species), where mycothione replaces glutathione. [Cellular processes, Detoxification].	0
NZ_CP024985.1|WP_030229753.1|1020064_1021255_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.89243e-146
NZ_CP024985.1|WP_030229752.1|1021251_1022244_-|NADPH:quinone-oxidoreductase-family-protein	gnl|CDD|176203	cd08241, QOR1, Quinone oxidoreductase (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	5.34072e-133
NZ_CP024985.1|WP_030229735.1|1037350_1039048_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.41043e-93
NZ_CP024985.1|WP_030229747.1|1026350_1027115_-|PIG-L-family-deacetylase	gnl|CDD|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	8.33101e-30
NZ_CP024985.1|WP_030229750.1|1023723_1024623_+|SDR-family-oxidoreductase	gnl|CDD|187627	cd05369, TER_DECR_SDR_a, Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR. TTER is a peroxisomal protein with a proposed role in fatty acid elongation. Fatty acid synthesis is known to occur in the both endoplasmic reticulum and mitochondria; peroxisomal TER has been proposed as an additional fatty acid elongation system, it reduces the double bond at C-2 as the last step of elongation. This system resembles the mitochondrial system in that acetyl-CoA is used as a carbon donor. TER may also function in phytol metabolism, reducting phytenoyl-CoA to phytanoyl-CoA in peroxisomes. DECR processes double bonds in fatty acids to increase their utility in fatty acid metabolism; it reduces 2,4-dienoyl-CoA to an enoyl-CoA. DECR is active in mitochondria and peroxisomes. This subgroup has the Gly-rich NAD-binding motif of the classical SDR family, but does not display strong identity to the canonical active site tetrad, and lacks the characteristic Tyr at the usual position. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	5.26504e-99
NZ_CP024985.1|WP_030229743.1|1029476_1030451_-|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.62683e-45
NZ_CP024985.1|WP_158740639.1|1022535_1023669_+|hypothetical-protein	gnl|CDD|379369	pfam13786, DUF4179, Domain of unknown function (DUF4179).	0.00391826
NZ_CP024985.1|WP_030229736.1|1036376_1037276_-|squalene/phytoene-synthase-family-protein	gnl|CDD|366130	pfam00494, SQS_PSY, Squalene/phytoene synthase.	4.98512e-20
NZ_CP024985.1|WP_030229754.1|1018949_1020068_-|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	1.52603e-37
NZ_CP024985.1|WP_030229741.1|1031894_1032698_+|transglycosylase-SLT-domain-containing-protein	gnl|CDD|381605	cd13402, LT_TF-like, lytic transglycosylase-like domain of tail fiber-like proteins and similar domains. These tail fiber-like proteins are multi-domain proteins that include a lytic transglycosylase (LT) domain. Members of the LT family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, and the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL). LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.4074e-29
NZ_CP024985.1|WP_051840833.1|1030521_1031442_+|dihydrodipicolinate-synthase	gnl|CDD|188637	cd00950, DHDPS, Dihydrodipicolinate synthase (DHDPS). Dihydrodipicolinate synthase (DHDPS) is a key enzyme in lysine biosynthesis. It catalyzes the aldol condensation of L-aspartate-beta- semialdehyde and pyruvate to dihydropicolinic acid via a Schiff base formation between pyruvate and a lysine residue. The functional enzyme is a homotetramer consisting of a dimer of dimers. DHDPS is member of dihydrodipicolinate synthase family that comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways.	9.69506e-80
NZ_CP024985.1|WP_100661246.1|1033324_1034557_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	4.4513e-43
NZ_CP024985.1|WP_030229748.1|1025455_1026292_-|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	5.30608e-58

Protein sequences

>NZ_CP024985.1|WP_030229747.1|1026350_1027115_-|PIG-L-family-deacetylase
MTERADQQAPLQPMPTDWQRALAVVAHPDDLEYGCAAAIADWTDGGREVVYVLATRGEAGIDTVTPDECAPLREAEQRASAAVVGVSTVEFLGHRDGVVEYGLGLRRDIAAAIRRHRPELVITLNHRDTWGGPDGGGYWNTPDHRAVGRAALDAAADAGNRWIFPELISEQGLEPWNGVRWVAVAGTATPTHAADATPGLERSVRSLMEHKAYIEVLTDQDPEEYVRSFLTGNAERNAARFGGRPAVAFEVFPR
>NZ_CP024985.1|WP_030229748.1|1025455_1026292_-|enoyl-CoA-hydratase/isomerase-family-protein
MIDTVSTETGEGAERRVRLDVEDGIALLTLCRPDKLNGWSWESTRQLGLLADRIRFDPSVRAVLLRAEGRAFCAGIDVTAPGGAITGDSPAERTHNYYEGIRWVHERFAVLARLPQPVIAAVQGYCLGFGFELALMADIRIAADDAVFALPEAGLGVAVDAGGDLRIAREAGAGWAKFLALTGRRIDAATAERLHLVQLVVPPGLLEEASRELAAEIAANAPLAVQGIKRGIDAYADAALPAALDRVAMTAALTLTSEDSREGYRAKAARRPPHFRGA
>NZ_CP024985.1|WP_030229749.1|1024668_1025469_+|hypothetical-protein
MMHADLTFERWRSLDLDAARRFAGEAAARVDARVLTVETVEHLGAPLHRVRIVREGMEFALVPGGRVRLGFDPDAWTATPAQEADFAESLAEGYGFGAHDLKGHLVAELSPLRTVELPTVWMAVEAEPAPEPEDGLVAPLAARGLRLPGADEWEHACGAGARTLFRWGDECPLDEAPYGAGGIRNEPNAFGLRIAHDSYSAELSEDRGAVHGGDGGTAVCGGYGNLLGWLPLATAHRNADMAEFVYGPDGEYAWETFSVRPVLTLP
>NZ_CP024985.1|WP_030229750.1|1023723_1024623_+|SDR-family-oxidoreductase
MTDNARRGLPAPPPLGAAALPPGTFAGQVVLVTGGGTGLGKAIAAEFARLGAGLVIAGRRAEPLGAARAELAAVPGAGRVAAAVCDIRDPERVAEVFDAAEAALGPPDVLVNNAAANFPCPAEDLSPNAWRAVVDTTLTGTWFTTREFARRHLAAGTPGSIVNIGASYAWTGGPGFAHSAASKAGVKNLVETLAVEWGPYGIQINGLVPGLVPHPDMSADIRGGLERAAPGDRDDRQPALRVGAPRELGWAATFLASPYARFVTGHTLVVDGANWQRRSLVQPGVVPVREQLGRPPFSP
>NZ_CP024985.1|WP_158740639.1|1022535_1023669_+|hypothetical-protein
MNRTPMRRGASAAAAAIVLAGIVTAAGPASAATTCTPRIQVLGSIGSSLHNPGNRQAEGVNDLGKGNLSVGVSGGLPVYWTGTTLHKVPLPAAGLDGELLAVNKDGLMVGRIFTGGGYVFTYRAGDAAIAPLPGSDDPYGEADVNDAGYVVSRNRAGVGLVWKDGRKVRELAPPANSDPHTRVDLVTGINNRGDILGTAKVDYTDDGDNQHWDVTPVLWPADGGPAVPLAPSGGGKYQESFVQGLDESGRVVGYDWYGPGYAYKPWTWTPPYTAPGTSPGLLNPFPYGTFEAISPTTNVSVGTAKFHPDEPTQADQAQLWPGSGPLLALPRLAADKASMAESVSDDGRVGGAAVNAKGKLKPVIWTCATKQAYLPKP
>NZ_CP024985.1|WP_030229752.1|1021251_1022244_-|NADPH:quinone-oxidoreductase-family-protein
MQAWRVHTTGEPREAMRLEEVPEPVPGEGEVRLRVLAANVNFPDALLVRGQYQIKPPLPFTPGVEICGETEDGRRVIANPSLPHGGFAEYVTAPARALLPAPGTLDDAEAAALHIGYQTGWFGLHRRARLQRGETLLVHAAAGGVGSAAVQLGKAAGATVIGVVGGKAKARTAEELGCDLVIDRTAEDLVARVKEFTAGRGADVVYDPVGGDAYTASAKCVAFEGRIVVVGFAGGTVPTPALNHALVKNYSILGLHWGLYAAKDPAAVLACHTELTRLAAEGLVKPLVSERVPLAAAADAVQRLADGTTTGRLVVVPSAPAAPAADGAGR
>NZ_CP024985.1|WP_030229753.1|1020064_1021255_-|acyl-CoA-dehydrogenase
MTPTAEDLAARTRALLAAHPPATTSRPDFLAARFDAGLAWVHYPEGLGGLGAPRSLQAVVDAELEAAGAPDNDPRRIGIGLGMAAPTILAYGTEEQKRRFLRPLWLGEEVWCQLFSEPGAGSDLAALGTRAVLDDTTGEWVVDGQKVWTSSAHTARWAILIARTDPTLPKHRGITYFLCDMHAPGVEVRPLRQITGEAEFNEVFLTGVRIPDAHRLGAVGQGWAVARTTLMNERVSIGGMRIPREGGMIGPVAAVWRERPQLRTHALHQRLLGLWVEAEVARLTGERLRQQLVAGQPGPEGSGMKLTFARLNQEISGLEVELLGEEGLLYGDWTLRRPETVDFTGRDAGYRYLRAKGNSIEGGTSEILLNIVAERVLGLPAEPRDDKDIAWKDLAR
>NZ_CP024985.1|WP_030229754.1|1018949_1020068_-|acyl-CoA/acyl-ACP-dehydrogenase
MTASRASLDLLYSDTEEELRFAVRALLADHCAPATVLARAESGRPHDPALWRTLASGIGAAGLLVPEKLGGAGASHREAAVVLEELGRAVAPVPYLTGCVLATEILLGCDTPEAADLLRALAAGQQVCVPALPLTQAPGAPLPQPLRDTGGGALTGTATSVADATAADVLLVLADTGLYAVPAAGARLTGAVPLDLTRPLATVTLDGTPGTRLADPATARAAVAGALLSGAGLLASEQLGLAEWCLTETVAHVRGRHQFNRPIGSFQALKHRLARLWLDVASARAAARAAADALATASPDAPLTVAVAQAYCSGVAVRAAEECVQLHGGIGMTWEHPAHLYLKRAKSDSLALGTTGHHLGLVADFAELPAPA
>NZ_CP024985.1|WP_030229755.1|1018138_1018912_+|hypothetical-protein
MVERLVELSTRLQEMWESTPTVALPGWGHPFRSLAELLPERDLLLADRNPQMVPLLWYPALRAHGPAGPVVEVFDHLPGDRPASPLMLRRQDLAGLYSWAVCTASAVEWIGAVTAGAPLVEVGAGSGYWARQLSLAGVGVVATDLHPVEGNGFTHGFRYAEVETFAAADAVRRHPGHTLLLVWPPPADPMAVRALRAYRGELFLYVGEGPGGMCADAAFFAELDRHWTAEAVCPLTVRWLGHADGITLYRRRRPVLP
>NZ_CP024985.1|WP_030229756.1|1017923_1018124_+|hypothetical-protein
MNPTARNAAVVAAAVAALTGAATAGSASPADPADRDGISVVAHMAMLSTPTPAEDTLATVQHGYLS
>NZ_CP024985.1|WP_051840835.1|1028317_1029439_-|S-(hydroxymethyl)mycothiol-dehydrogenase
MIQTDPNRTGYDVTHRVRGVIARSKGAPVETTTILVPDPGPGEALVKIQACGVCHTDLHYREGGINDEFPFLLGHEAAGVVESVGPDVTSVAPGDFVVLNWRAVCGTCRACRRGRPWYCFATHNATQPMTLEDGTPLSPALGIGAFAEKTLVAAGQCTKVDPAASPAAAGLLGCGVMAGLGAAINTGNVGRGDSVAVIGCGGVGNAAVAGARLAGASKIIAVDLDDRKLEWARGLGATHTVNGRTEEVVKAIQGLTDGNGADVVIEAVGRPETYRQAFYARDLAGTVVLVGVPTPEMKLELPLLDVFGRGGALKSSWYGDCLPERDFPLLIDLYLQGRLDLDAFVSETIPLDGVEDAFARMERGEVLRSVVQF
>NZ_CP024985.1|WP_030229743.1|1029476_1030451_-|LysR-family-transcriptional-regulator
MLDVRRLRLLRELARRGTIAAVAQALSFSPSAVSQQLSALEREAGLPLLERTGRTVRLTPAAQNLVRHADAVLERLERADADLAEARSGLAGALRIGAFPTATRAIVPAALVHLARRHPGLEPMVSETDPAAVAHALRAGDLDVALVHEYDLVPEPPEPGLATRQLYGEAMYLAGPAPATAADPGSFPGAADPGAPPAGSPGQDAVLRAHRDDPWITATPGTLCHAMTVRACRAAGFTPRVRHQVDEFATVLALVAVGQGVAVVPQLGVTGPTGPGVSLVRLHMERRTKIAFRSGAGAHPAVAAFTAALRAAVPPDLAAARAES
>NZ_CP024985.1|WP_051840833.1|1030521_1031442_+|dihydrodipicolinate-synthase
MRLDTHGTTTDTTALDGIHVPLITPFDRAGNIAAEALEALAHEALDAGAAGIVALGTTGETATLEEAERDLVTEVCARVCRERGGLLTVGAGASGTRAAEASLARLVRWPQVGAALVTVPSFVRPAAAGVLAHFTRLAEVSPVPLVVYHIPYRTGQPLDAAALRALGALPGVAGLKYAGGGVDQETVALLGDLPDGFAVLAGDDAYLSPMLALGAAGGILASAHLATERFVELAAAWRAGDVPRARSLGHALARLSAAAFAEPNPTVVKGVLHAQGRIPTPDVRLPLLPASPAAVAATLKELAEIQ
>NZ_CP024985.1|WP_030229741.1|1031894_1032698_+|transglycosylase-SLT-domain-containing-protein
MSAKGKHRRPKQHRIARRLAFAGTGGAALALPLIGATTAGAAVTQPAVAPATSTLARPAVQPAVQPAVQPAVQPAVQPAAENAALPLTYSVVGGDTLSKIAADHSVSGGWQTLYADNRSAIGADPSVIRPGLTLRLGAAAKASAAKATAVTAAAVKPAATYANNLDGWIRESLDIMARHGIPGSYNGIHRNVMRESSGNPLAINNWDSNAAAGIPSKGLLQVIDPTFRAYHVPGTAMDSYDPVANITAACNYAAARYGSIDNVNGAY
>NZ_CP024985.1|WP_030229740.1|1032722_1033328_-|response-regulator-transcription-factor
MIRVLLAEDQGMMRGALALLLGLEEDIEVVAQVGAGDEILAAALDARPDVALLDIELPGRSGLDAAAELRSRLPGCRVLILTTFGRPGYLRRAMEAGAAGFLVKDGPVEELAVAVRRVLAGEKVIDPSLAAAALSAGPNPLTPREIDVLVAAADGATVADIAGRVHLSESTVRNYLSAAIGKTGTRNRMEAVRAARRQGWL
>NZ_CP024985.1|WP_100661246.1|1033324_1034557_-|sensor-histidine-kinase
MRSGQGTGREREPDWQVRRIARRAAQRARRARGCAPGGGPDPVAGPPNALTLLPWLLLGMGALSNIVQGKTPNPWVGVVGLLAFNSLYVTLVFRAFHKEAREAPATRWCLVALGAVTCALALAYGGNWLLFFPLLGLATGAVVRGRRLGPVMFAVTTVAAVVAGRSGGMDTLGIAYGTLLSGMVTAAILALSETVKKLRDTRQELARAAVDQERLRFSRDLHDLLGHTLSVIVVKSEAARRIAPRDMDAALEQVRDIESVGRQALTEIREAVTGYREASLAAELDRARGALTAAGIEPVVRQSGPPLPPQTAALLGWVVREAATNAIRHSGAATCEIELRSSAERAVLVITDDGNGVGSNPPGSGLTGLGERLALAGGTLGSGPAPDRGFRVTAELPVEPTGEEEDGERG
>NZ_CP024985.1|WP_167456818.1|1034578_1035295_-|ABC-transporter-permease
MTAYVRLEVRRTLRDVSFVVFGIGMPVLMYLLFTNLGGVDPEWRTASMVAMAAYGALGAALSTGTGVAEDKGSGWLRQLRVTPMTPRQVVTGRALTGSVIVLPAIAAVLAAGACVNGVRMDAWQWAAVALVLWLGALPFTLLGIGNGYRLTAQSTGMVNVGWSLALSILGGLWFPVEAFPGWLRSLSGLTPTRRFAELGQSLAAGAAPGAAAAAVVGVWALLFASYAVLSYRRSARTV
>NZ_CP024985.1|WP_100660780.1|1035294_1036290_-|ABC-transporter-ATP-binding-protein
MTKPPSAAHPARTAPRQLPDPDGDAPAIRFRHAAKSFGAVRAVAGLDLDVRRGETVALLGRNGAGKSTTIALLLGLDEPDAGSVRLFGRTPAEAVRAGRVGAMLQEGRPVARITVRELVAFAARTYPAPLPVAEALDLAGLTDLAGRRVDRLSGGQAQRVRFAVALAGNPELIVLDEPTAALDVESRRAFWRSMRAYARRGNTVLFSTHYLEEADAHADRILVLDRGRTVADGTGEQLRRTAARGSMVCVDLAGRPSGGLAALPGVDAVEVRGDRARLRTRDPDATVTALAALGAVRGIEVTPPSLDDVFLALTGATAPTPSASAPGENAR
>NZ_CP024985.1|WP_030229736.1|1036376_1037276_-|squalene/phytoene-synthase-family-protein
MPSWRTTLTRAGITTPRLRDDYTHAARRVLRREPAPYATLRLLAAPPLVPWLTAGLAFMNRVDDVAETGTPAERAAATTALAGRVEAALASGDSPDPLLRAYAHAVRTRGLPGSWVTRFLDGAATAEAAFDGFAAEEDFQAYLDAYAWPGVLVFTGLQYEGGPDPEQAAGWRRFVDAAQRVDFLADLSGDLAEGRLCIPRARLDEHGVTRADLEQARETPAVRALLDAEARRARSALAATDGILDLAEPGLRPVIAAMTELMDHQLTAVERVGTAILRRDTGYGLVAPLRTLLRARAGR
>NZ_CP024985.1|WP_030229735.1|1037350_1039048_-|serine/threonine-protein-kinase
MDTSEAGRRLVDRRFELIGPLGAGGMGTVWRARDIALHREVALKEVRPPDPATAAAQPGLAVQLRERAVREARALARLAHPNVVTIHHIVEPEAGMEDHPWIVMELVKGGSLYDRLAAGPMPLGEVLRLGLDVLSALRAAHAEGVLHRDVKPANVLLRPDGGAVLTDFGIAALHGATALTSTGVLIGSPEYIAPERARGEEGLAASDLWSLGMLLYVAAEGTHPLRRSTSLATVVAVLEDPIPAPVRSGPLGPVLQRLLVRDPAARPDGAALEALLRDASTALAAGTPGSHPAAPHPYGPPAPATPAVPPGAYAPYAPHAPGPAPASTVPVAREDGRRRPRALPAVLLAAVLAAGIYGAVQWLPDGDTGTGAGAKPGGGASLPATAGPAGSTPSGSGPAAPPLGPRTSAPASQAATAPKGTLLTPDRIRTALAALKQQTGTTTFAKMTVYDEYVIASVPTAAGAETLDYWEYRGGSVRHTGPAGTVKDGDPLIDMAAVGWDALPALLETSTREIGLQKPSSRYVIVDPWMMDQVPCMRTYLSDEYGRGGYVLAGTDGQVKKVVKF

Crispr_ID: NZ_CP024985_9

• CRISPR_ID: NZ_CP024985_9
• CRISPR_location: 1406242-1406475
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP024985_9

Consensus_repeat	Method
AGCGGGGGCGCCGTCTCGTCCAGGGGC	CRISPRCasFinder

spacers of NZ_CP024985_9

>9.1|1406269|36|NZ_CP024985|CRISPRCasFinder
CCGGCGGGCAGGTCCAGGGGAGGCGCCGTCTCCGCA
>9.2|1406332|33|NZ_CP024985|CRISPRCasFinder
GCCGTTTCCTTCAGGGGAGGCGCCGTCTCGTTC
>9.3|1406392|57|NZ_CP024985|CRISPRCasFinder
CCGGCCGACGGGCCGAGGAGGGGTGCGGCGGCGTTCGGAGGCCCGGCCGGCAGGTCG

CRISPR arrays and Neighbor proteins around NZ_CP024985_9

CRISPR arrays

The CRISPR arrays of NZ_CP024985_9

>merge|NZ_CP024985|9|1406242-1406475|CRISPRCasFinder
AGGGGCGGGGCCGTCTCGTCGACCGGTCCGGCGGGCAGGTCCAGGGGAGGCGCCGTCTCCGCAAGCGGGGGCGCCGTCTCGTCCAGGGGCGCCGTTTCCTTCAGGGGAGGCGCCGTCTCGTTCAGCGGGGGTGCCGTCTCGTCCAGGGGCCCGGCCGACGGGCCGAGGAGGGGTGCGGCGGCGTTCGGAGGCCCGGCCGGCAGGTCGAGCGGGGGTGCGGTCTCCGCCAGCGGG

>NZ_CP024985|9|10|1406242-1406475|CRISPRCasFinder
AGGGGCGGGGCCGTCTCGTCGACCGGT	CCGGCGGGCAGGTCCAGGGGAGGCGCCGTCTCCGCA
AGCGGGGGCGCCGTCTCGTCCAGGGGC	GCCGTTTCCTTCAGGGGAGGCGCCGTCTCGTTC
AGCGGGGGTGCCGTCTCGTCCAGGGGC	CCGGCCGACGGGCCGAGGAGGGGTGCGGCGGCGTTCGGAGGCCCGGCCGGCAGGTCG
AGCGGGGGTGCGGTCTCCGCCAGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_078950035.1|1400545_1401184_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379256
NZ_CP024985.1|WP_167456775.1|1411770_1411941_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_051840160.1|1401188_1402274_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP024985.1|WP_030224220.1|1402832_1403693_-|Fpg/Nei-family-DNA-glycosylase	unknown	unknown	gnl|CDD|223344
NZ_CP024985.1|WP_051840157.1|1399086_1400463_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_051840050.1|1398494_1398959_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030224203.1|1395625_1396087_+|universal-stress-protein	unknown	unknown	gnl|CDD|366180
NZ_CP024985.1|WP_037686021.1|1407714_1408617_+|YndJ-family-transporter	unknown	unknown	gnl|CDD|372935
NZ_CP024985.1|WP_030224232.1|1408642_1409185_+|DUF1990-domain-containing-protein	unknown	unknown	gnl|CDD|378157
NZ_CP024985.1|WP_030224261.1|1417105_1417759_-|arylsulfatase	unknown	unknown	gnl|CDD|376478
NZ_CP024985.1|WP_030224235.1|1409196_1410636_+|lipase-maturation-factor-family-protein	unknown	unknown	gnl|CDD|369070
NZ_CP024985.1|WP_030224207.1|1397704_1398238_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|236605
NZ_CP024985.1|WP_030224217.1|1402409_1402805_-|hypothetical-protein	unknown	unknown	gnl|CDD|376764
NZ_CP024985.1|WP_030224258.1|1415370_1416711_-|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|366703
NZ_CP024985.1|WP_030224253.1|1412765_1414241_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|237218
NZ_CP024985.1|WP_030224205.1|1396223_1397438_-|CapA-family-protein	unknown	unknown	gnl|CDD|378215
NZ_CP024985.1|WP_100660797.1|1403791_1405765_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP024985.1|WP_030224266.1|1418108_1418528_-|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|376751
NZ_CP024985.1|WP_030224264.1|1417752_1418094_-|N-acetyltransferase	unknown	unknown	gnl|CDD|379642
NZ_CP024985.1|WP_030224238.1|1410621_1411599_-|reductase	unknown	unknown	gnl|CDD|187575

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_078950035.1|1400545_1401184_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379256	pfam13551, HTH_29, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	1.36779e-07
NZ_CP024985.1|WP_051840160.1|1401188_1402274_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.75269e-25
NZ_CP024985.1|WP_030224217.1|1402409_1402805_-|hypothetical-protein	gnl|CDD|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	0.00677488
NZ_CP024985.1|WP_030224220.1|1402832_1403693_-|Fpg/Nei-family-DNA-glycosylase	gnl|CDD|223344	COG0266, Nei, Formamidopyrimidine-DNA glycosylase [DNA replication, recombination, and repair].	2.23176e-60
NZ_CP024985.1|WP_030224232.1|1408642_1409185_+|DUF1990-domain-containing-protein	gnl|CDD|378157	pfam09348, DUF1990, Domain of unknown function (DUF1990). This family of proteins are functionally uncharacterized.	3.9753e-59
NZ_CP024985.1|WP_030224235.1|1409196_1410636_+|lipase-maturation-factor-family-protein	gnl|CDD|369070	pfam06762, LMF1, Lipase maturation factor. This family of transmembrane proteins includes the lipase maturation factor, LMF1. Lipoprotein lipase and hepatic lipase require LMF1 to fold into their active states. The precise role of LMF1 in lipase folding has yet to be determined.	1.84422e-148
NZ_CP024985.1|WP_037686021.1|1407714_1408617_+|YndJ-family-transporter	gnl|CDD|372935	pfam14158, YndJ, YndJ-like protein. The YndJ-like protein family includes the B. subtilis YndJ protein, which is functionally uncharacterized. This family is found in bacteria and archaea, and is typically between 222 and 269 amino acids in length. There are two completely conserved G residues that may be functionally important.	1.317e-61
NZ_CP024985.1|WP_030224261.1|1417105_1417759_-|arylsulfatase	gnl|CDD|376478	pfam01177, Asp_Glu_race, Asp/Glu/Hydantoin racemase. This family contains aspartate racemase, maleate isomerases EC:5.2.1.1, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase EC:4.1.1.76.	0.00531109
NZ_CP024985.1|WP_030224203.1|1395625_1396087_+|universal-stress-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.58993e-22
NZ_CP024985.1|WP_030224207.1|1397704_1398238_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|236605	PRK09645, PRK09645, ECF RNA polymerase sigma factor SigL.	6.92922e-66
NZ_CP024985.1|WP_030224258.1|1415370_1416711_-|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	4.95212e-40
NZ_CP024985.1|WP_030224253.1|1412765_1414241_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|237218	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	2.49091e-13
NZ_CP024985.1|WP_030224205.1|1396223_1397438_-|CapA-family-protein	gnl|CDD|378215	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap. This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein.	1.24807e-83
NZ_CP024985.1|WP_100660797.1|1403791_1405765_-|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	8.00154e-50
NZ_CP024985.1|WP_030224266.1|1418108_1418528_-|aspartate-1-decarboxylase	gnl|CDD|376751	pfam02261, Asp_decarbox, Aspartate decarboxylase. Decarboxylation of aspartate is the major route of beta-alanine production in bacteria, and is catalyzed by the enzyme aspartate decarboxylase EC:4.1.1.11 which requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. This family contains both chains of aspartate decarboxylase.	1.35416e-79
NZ_CP024985.1|WP_030224264.1|1417752_1418094_-|N-acetyltransferase	gnl|CDD|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	6.63208e-17
NZ_CP024985.1|WP_030224238.1|1410621_1411599_-|reductase	gnl|CDD|187575	cd05265, SDR_a1, atypical (a) SDRs, subgroup 1. Atypical SDRs in this subgroup are poorly defined and have been identified putatively as isoflavones reductase, sugar dehydratase, mRNA binding protein etc. Atypical SDRs are distinct from classical SDRs. Members of this subgroup retain the canonical active site triad (though not the upstream Asn found in most SDRs) but have an unusual putative glycine-rich NAD(P)-binding motif, GGXXXXG, in the usual location. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.09517e-72

Protein sequences

>NZ_CP024985.1|WP_100660797.1|1403791_1405765_-|SpoIIE-family-protein-phosphatase
MGSFDWDLVTGLMHLDAAALDVFDTTPDAYDGRPESLGPRVPPAESARLDALVSSALKGGLDSYGAYFRIRCHDGRLRWTHTQGRVMRDDAGRPYRIIGIVRDATEELSHSAERLGLDDERRRQTSVVESTTAALAHARTVKDVIDALGDAHGLERLGSMGMVMGLVEAGRIHLVAEGPPGSFVPGTRYTRIDEQYPMSEVVRSLQPRFLDSAQEFAEGYPGLWARISSMDISAAAYLPLIAQARPIGAIGLLYQDKDGFTQDERNLLVALGSSIAQSLQRAMLLEQEHDLAEGLQQAMLPRRIPSVPGAQIAVRYRSARMGQDIGGDWYDVIPLPGGRVGAVIGDVQGHDTHAAAVMGQLRIVLRAYAAEGHSPATVMARASVFLHELDTDRFATCTYAEADLTTGVLQIVRAGHIDPLLRTRDGDCRRLPVEGGMPLGLSAEFGRLEYPVATVELDPGETLLMCTDGLVEQPGADLDDGIRFLADLVRGGPGDLQLLADRLCEVVDDRGDDDMALILLRRRGDDVPQGGGRLQQHVAPGDPEALVAARHMIGAAVRAWGARGRADEIELVADELIVNALMHTDGPAIVTLRVLTGTQRRLRVEVEDRSSALPRRREAGDSGVSGRGLMLVDRLADVWGVEPRGSGKCVWCEFVMD
>NZ_CP024985.1|WP_030224220.1|1402832_1403693_-|Fpg/Nei-family-DNA-glycosylase
MPELPEVEALRGFLEERLTGRVVRRVLPLAVSVLKTYDPPLTALEGGRAGPVARYGKFLDLGVGDLHLVTHLARAGWLRWHDTFPARPPGPGKGPLALRVELEEGGGFDLTEAGTQKRLAVYVVRDPREVPGIARLGPDPLAEGFDRDAFAALLAGERRQIKGVLRDQSVIAGIGNAYSDEILHTARVSPFKLAASFDEDQVTHLYRAVEDTLRTAVERARGVAAGQLKAEKKSGLQVHGRAGEPCPVCGDTVRSVSFADSSLQYCPTCQTGGKPLADRRLSRLLK
>NZ_CP024985.1|WP_030224217.1|1402409_1402805_-|hypothetical-protein
MAQDQQRPQPRREIVTGVPRGARRRPPAHTPARSEISEQTTLGATYVRALMRSQLRAAVVALALLALLLGLLPLGFLLSRAVAGPVVWVALGVVAYPVMWLIARWYVARAERNEAAFTGLITDPAEPPPTA
>NZ_CP024985.1|WP_051840160.1|1401188_1402274_-|pentapeptide-repeat-containing-protein
MAAGLAVLAALAVVVVVLPGLVVERDLGGAGISAAERLTAVNNVRTTLVQAVGGAVVLFGAYATWRQLRVNQEGLNATREGHITDRFGRAVDQLGSEKTDVRIGGLYALWRIADHSAHDREAVISIKAAFLRTHLPWPPQAQDAPAAEASINSVPPLETRAPDAQVALTGLGVLCQERQPDWLNVSYTDLRRADCDGLWLHHINFDGACLEAASIYQVNLTRASLIAANMRHVELGTSILHQSRCIEADLRGARMVRADLREADFSGADLREANLRKARGHGAKFTGADLRLADLRGTDLTSADLTGAKLEGALASDVTIWPAGFDIQAAGVVMVEDPGAEPSILLQAAALARNVPPLHSA
>NZ_CP024985.1|WP_078950035.1|1400545_1401184_+|helix-turn-helix-domain-containing-protein
MAQPVRVRRLTEQKGQKVQRIVRRGSTSSVRFRRAMMPMASAGGSTVPVIARLVQADEDTGRDVIHRFNEIGLACLNPQWAGGRPRLLSRDDEDFVVQTATTRPTQVGKPFTRWSIRKLADHPRRNIARPIRIGREALRCLPARRGISFQRTKTWKESPDMAFDAKLERIEYAINERPDRTFAFDELGPLGIRPTAGSCWAEETRPDRDYLD
>NZ_CP024985.1|WP_051840157.1|1399086_1400463_+|hypothetical-protein
MPPAARAELARTAWAELPHRCSGRHGVPDTPDVLAGVLSADPAHRVRAVGNLYRLLLDRDGLFPATAPAALVLAALLDDPRTLAEDRWERRPGRRPLRAELLNWLASFADIARRGVEDGIDSARDPAAARAARPALRARVAVFCEDDDPRVREAALAATALLLADPALAPSAPRYAPAVRALLATSPDSYHRWIARERLAAWGEDVADLVAAEEGRRAALARAQAEDPFGEDQERAVRWLAEQREDTAALEPAGLGHGDRTVPAPQDPPGPAPEPPVAVPGSMAGYRGPWRLARAEERAEWTFTPYVGVGPLHFGMTLDEITTALGEHPAASSHTHDGTHRRLESADFTTSGIRALFRDDRLGCVAVNALGGPQVRLDGAPLTGCAPSRVEDWLVHRTERTRPGSLRYSPAGDPVFAGLGLAIRGQRAGDLVLTRPLFLHHDWLDLWHALPAAEWNHP
>NZ_CP024985.1|WP_051840050.1|1398494_1398959_+|hypothetical-protein
MAWLYAEYIADELLRTGRLIPVSTLEFRAGRDTLALTIYLSDAAGELSGIRVVSQLEEWLSLTAYGHPWRDWVHTRFLALGEEARERGRGDDPDLELARAAWRWLDRTELFATNLDPGRLGHGDTAAGLDENARVWTPAWQLGLPLGHLAMHLF
>NZ_CP024985.1|WP_030224207.1|1397704_1398238_+|sigma-70-family-RNA-polymerase-sigma-factor
MPPTPTLQRTEPEALAELQREHGRALFGFLLGLTAGDAQRAEDLVQETLVRVWQHPEVLRTGHESMRPWLFTVARRLAIDARRARLSRPQEVDPDGLEQAPAPEDAVAGSVTAIDVRRAVGSLGQEHRDVLLQVYFRDRSVAEAAAELGIPAGTVKSRTYYALRALRKGLQGYGLGA
>NZ_CP024985.1|WP_030224205.1|1396223_1397438_-|CapA-family-protein
MTKGTRRALALLSALLLSAAAAGCSTGSEPAPARLGSRPAGAPQGSTGPTAPAAPGTPKGFTLVASGDVLPHTSIIQRAAADAGGDGYDFRPMFSGVKPVVSAADLALCHMETTYGEDAGPFSGYPAFVSPPAVADALKDAGYDGCSTASNHTLDDGADGLKRTLDRFDKVGLGHAGSARTAAEAARTTFYTAGSAKVAHLAYTYDTNGYPMPDGQPWAVNLMEPDKIIADARLARKAGADVVLVSLHWGTEWQTEPDETQLSLGKTLTASRTGGRPDVDMILGTHAHIPQAYEKVGGGWIVYGMGDQVAGEMFNHSGARDMRGNYGSIGRFTFAPPTAPGGRWQVTKAEFIPQMMDLSTGRIVNLPAALAEEPGQSEYETAQEAVTEAVLSRGAAKDGLTRAR
>NZ_CP024985.1|WP_030224203.1|1395625_1396087_+|universal-stress-protein
MTEHVNTGFERGTDGPKVILAGIDGSESSLRAAAYAAGLARRQNALLALVYVQPVMAAGASLGAPVGEATGEIAEGLIAEVRASAERLKGIFEVRWQFHTFRGDPYQGLVSAAGELKADAVVVGASERAGHRIVGSVAVRLVKAGRWPVTVVP
>NZ_CP024985.1|WP_037686021.1|1407714_1408617_+|YndJ-family-transporter
MTVLVNLIVALGAVCAVPLGLRLIDPVGLRRAARLWPLAAVPGALCLWLPRGPAATALALLYAAAALALAATAGARLRQGLAGTRPGGRRLPDPAGAAVLTALVSPSVAATALVAERAGYPLFGFDLDVLALTVPHFHFAGFTAALVAGLVCRSSGTRPARWAAYSVPAGTLLVLLGYFVDDWAELLGAVVLTTGMWAVALVTWRDLRPAARDRTTAALLGVSAAVLVAAMLLALWWAAGEATGIVHPTLTWMAATHGLGNALGFALCSLLAWRRLTAPPVPSSSSAPPVAPAPAPAPRP
>NZ_CP024985.1|WP_030224232.1|1408642_1409185_+|DUF1990-domain-containing-protein
MTRLISAGRDTVNYPDRGATARRPLPAGYNHLHQRTRIGRGRAVFEAAGTAVTTFHAHRASGVRVRTPGGEGTAVRPGLRAEVGLGLGPLRITAPCQVIWTAYEPTRVGFAYGTLAGHPECGEESFLVEIDADGAVWFTVTAFSRPNRWYTRLAGPVVPLLQHGYARWLGRHLRALASGA
>NZ_CP024985.1|WP_030224235.1|1409196_1410636_+|lipase-maturation-factor-family-protein
MDWFTAPGYWLGRLVFQRALAGVYVFAFLGAALQFRALIGTRGMLPVPDYLRYVPFRHAPSLFQLRYSDGLFAGCAWAGAALAAALAAGAGDLVPLGAAMGMWAVLWLLYLSIVNVGQTWYSFGWESLLLEVGFLAVFLGNARTGPPVLVLWLLRWVLFRVEFGAGLIKMRGDACWRELTCLYHHHETQPMPGPLSWFFHRLPRPVHRVECAANHVTQLVFPVMLFTPQPVASFAACAMVATQLWLVLSGNFAWLNWLTITLALSAVDFGALTGPPPAAASGGAPVWYAVLVCAVTVLVLVLSRHPVANMISPRQVMNRSFDPLHLVNTYGAFGTVGRIRDEVVVEGTADEVPREDGAWREYGFKGKPGDPLRMPRQFAPYHLRLDWLMWFAALSPGYARDWFGPFVERLLAGDRDTLRLIRHNPFPDAPPRFVRARLYRYRFTTWRELRETGAWWHRRPVREYLPPTRLAGARASEPE
>NZ_CP024985.1|WP_030224238.1|1410621_1411599_-|reductase
MKLLMLGGTEFVGRAITEDALERGWEVTVFHRGHHAPPPGTSALHGDRTLPGGLDSLAEGEWDLVVDTWGGAPTAVRDSAHLLAGRAGRYAYVSTRSVYAYPAPASPDAPLVEGSPDADSVAYAEDKRGAEIAAVDAFGERALLVRAGLILGPYENVGRLPWWLNRVARGGPLLAPGRPGLPLQYIDVRDLAHWTLDAARAGLGGAYDLISPLGHATMGSLLEACAAATGVPLEPRWTDQALIEEAGIQPWTELPVWIPEGEAHTHMFGGDATRALETGLKCRPVEETAADTWAWLNSLGGVAPQRSDRPAPGLSAEREAALLGL
>NZ_CP024985.1|WP_167456775.1|1411770_1411941_-|hypothetical-protein
MTEMTKTDPTMERTGWRASTRSDELGSLEVWARSAPIRLAGYEDDLAEPHILPGID
>NZ_CP024985.1|WP_030224253.1|1412765_1414241_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTVTEDNHAYGPGIDPERLALCLSVLDELDKLDVDHPDAITVRRATAGLYRTVKQRRRQERRAAKTANDKAVTEATATGSAERIDDETEGILPSSVTEAGRIAGILQRPRSCYVCKTRYVEVDYFYHQLCPGCAAQNRAKREVRADLSGKRALLTGGRAKIGMYIALRLLRDGAHTTITTRFPKDAIRRFKAMEDSADWMHRLEVVGIDLRDPAQSVALAEQVAGAGPLDILINNATQTVRRLPTAYAALVEGESAPLPAGELPAHHVIGAFNSGAVDGLTALPVGVSGLEAQKVADLALVAGNASLERHLAGTAIDAGGLLPDVVESNTWVQTIDQISPVELLETQLCNYTSPFILISALRPAMAEAARKASSGRAYVVNVSAMEGVFSRGYKGAGHPNTNAAKAAMNMVTRTSGQEMFQTDRILMTSVDTGWITDERPHFDKLRLAEEGFHAPLDLVDGAARVYDPVVRGEAGEDLYGVFLKDYAPANW
>NZ_CP024985.1|WP_030224258.1|1415370_1416711_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MGVRGRHRRYQPSSINRASLAVTAGGAGIALPLIGAGAAHAASVDTWNKVAECEATGNWKINTGNGYFGGLQFSQSTWRDFGGTAFAARADLATKDQQIAVAEKVLRGQGPHAWPVCGPQSGLSRSGPAPATAGTASPKPVPSPSEPSRSRPAPAEQDRPEPARTQAPMDRLQATKATTGTPVTMPRPTGTSVLPNPYVVAPGDSLSTIAVEQHVEGGWQALYETNRSTVGGNPDMIFPGQRLTLRVTTAPAAPPAQNPEKPPRTAEPVKPVEPAGQAKPVEKPAEKPAEKPAEKPAPKPAEKPSAEQKPASGGFTAPVDAALGTAYRVAGSSWSSGYHTGVDFPVPTGTTIKAVGPGTVESAGWAGAYGYQVVIKHADGRYSQYAHLSALGVKAGQQVSGGQRIGRSGSTGNTSGPHLHFEMRTAPGYGSDIDPLKYLRGKGVGI
>NZ_CP024985.1|WP_030224261.1|1417105_1417759_-|arylsulfatase
MVTALTLLHTSGVHVPVFDALRDRDHPGAVLRHLVRPELLERARAHGPQAVAGELRGLLGGAGGPVLVTCSTLGAVAEALAPALGVPVLRVDRPMAAEAVRTGPRIAVLATLRSTLAPTGELLAEESAGRPVSVRTRLVEGAWDLFAAGDAAGHLALVAEAVDAVTDADVIVLAQASMAGAAPLARTRVPVLSSPGPGLAAALRLRGADTVSAFPGA
>NZ_CP024985.1|WP_030224264.1|1417752_1418094_-|N-acetyltransferase
MAIELLDEREAGRLLAVEDGAVVGFIAYFVLDAEPHALVAVHTVVEPGHEGRGIAGDLVGTFYGIAASEGVPVVPLCPYAASWAAKHPDRAPVPPAAVVEAAKAQLDADSGQW
>NZ_CP024985.1|WP_030224266.1|1418108_1418528_-|aspartate-1-decarboxylase
MLRTMFKSKIHRATVTQADLHYVGSVTIDADLLDAADLLPGELVHIVDITNGARLETYVIEGERGSGVIGINGAAAHLVHPGDLVILISYAQIEDAQARTFSPRVVHVDADNRIIELGSDPSAPVPGTDQERSPHAVAV

Crispr_ID: NZ_CP024985_10

• CRISPR_ID: NZ_CP024985_10
• CRISPR_location: 2233413-2233519
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_10

Consensus_repeat	Method
CGGCTGCTGGACCCGCTGCGCGAC	CRISPRCasFinder

spacers of NZ_CP024985_10

>10.1|2233437|59|NZ_CP024985|CRISPRCasFinder
TACGACCGCCGCCACCGCGCGGAGCTCATCCCGACCCTGGAGGCCTTCCTCGACTGCGA

CRISPR arrays and Neighbor proteins around NZ_CP024985_10

CRISPR arrays

The CRISPR arrays of NZ_CP024985_10

>merge|NZ_CP024985|10|2233413-2233519|CRISPRCasFinder
CGGCTGCTGGACCCGCTGCGCGACTACGACCGCCGCCACCGCGCGGAGCTCATCCCGACCCTGGAGGCCTTCCTCGACTGCGACGGCTCCTGGACCCGCTGCGCGAC

>NZ_CP024985|10|11|2233413-2233519|CRISPRCasFinder
CGGCTGCTGGACCCGCTGCGCGAC	TACGACCGCCGCCACCGCGCGGAGCTCATCCCGACCCTGGAGGCCTTCCTCGACTGCGA
CGGCTCCTGGACCCGCTGCGCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030234491.1|2237684_2238122_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NZ_CP024985.1|WP_030234478.1|2246644_2247130_+|DUF456-domain-containing-protein	unknown	unknown	gnl|CDD|377293
NZ_CP024985.1|WP_030234510.1|2227805_2230205_-|xanthine-dehydrogenase-subunit-D	unknown	unknown	gnl|CDD|132240
NZ_CP024985.1|WP_030234522.1|2219814_2222052_+|geosmin-synthase	unknown	unknown	gnl|CDD|173835
NZ_CP024985.1|WP_030234499.1|2234636_2235362_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP024985.1|WP_030234518.1|2223373_2224627_-|YncE-family-protein	unknown	unknown	gnl|CDD|225926
NZ_CP024985.1|WP_030234506.1|2230815_2231709_-|carbon-monoxide-dehydrogenase	unknown	unknown	gnl|CDD|224238
NZ_CP024985.1|WP_030234480.1|2245642_2246620_+|hypothetical-protein	unknown	unknown	gnl|CDD|224296
NZ_CP024985.1|WP_030234482.1|2241676_2245441_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173812
NZ_CP024985.1|WP_037687840.1|2233825_2234599_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030234513.1|2226022_2227486_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_CP024985.1|WP_030234508.1|2230207_2230813_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|224991
NZ_CP024985.1|WP_030234521.1|2222074_2223313_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|234945
NZ_CP024985.1|WP_030234485.1|2240068_2241574_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_CP024985.1|WP_030234494.1|2236535_2237600_+|DUF2637-domain-containing-protein	unknown	unknown	gnl|CDD|378511
NZ_CP024985.1|WP_030234525.1|2218538_2219630_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030234526.1|2218056_2218542_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP024985.1|WP_030234487.1|2238253_2239996_-|pyruvate-dehydrogenase	unknown	unknown	gnl|CDD|180614
NZ_CP024985.1|WP_030234516.1|2224799_2225951_-|XdhC-family-protein	unknown	unknown	gnl|CDD|224886
NZ_CP024985.1|WP_051841177.1|2235468_2236344_+|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|378676

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030234491.1|2237684_2238122_-|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	3.09698e-14
NZ_CP024985.1|WP_030234478.1|2246644_2247130_+|DUF456-domain-containing-protein	gnl|CDD|377293	pfam04306, DUF456, Protein of unknown function (DUF456). This family is a putative membrane protein that contains glycine zipper motifs.	3.22008e-19
NZ_CP024985.1|WP_030234510.1|2227805_2230205_-|xanthine-dehydrogenase-subunit-D	gnl|CDD|132240	TIGR03196, pucD, xanthine dehydrogenase D subunit. This gene has been characterized in B. subtilis as the molybdopterin binding-subunit of xanthine dehydrogenase (pucD), acting in conjunction with pucC, the FAD-binding subunit and pucE, the FeS-binding subunit. The more common XDH complex (GenProp0640) includes the xdhB gene which is related to pucD. It appears that most of the relatives of pucD outside of this narrow clade are involved in other processes as they are found in unrelated genomic contexts, contain the more common XDH complex and/or do not appear to process purines to allantoin.	0
NZ_CP024985.1|WP_030234522.1|2219814_2222052_+|geosmin-synthase	gnl|CDD|173835	cd00687, Terpene_cyclase_nonplant_C1, Non-plant Terpene Cyclases, Class 1. This CD includes terpenoid cyclases such as pentalenene synthase and aristolochene synthase which, using an all-trans pathway, catalyze the ionization of farnesyl diphosphate, followed by the formation of a macrocyclic intermediate by bond formation between C1 with either C10 (aristolochene synthase) or C11 (pentalenene synthase), resulting in production of tricyclic hydrocarbon pentalenene or bicyclic hydrocarbon aristolochene. As with other enzymes with the 'terpenoid synthase fold', they have two conserved metal binding motifs, proposed to coordinate Mg2+ ion-bridged binding of the diphosphate moiety of FPP to the enzymes. Metal-triggered substrate ionization initiates catalysis, and the alpha-barrel active site serves as a template to channel and stabilize the conformations of reactive carbocation intermediates through a complex cyclization cascade. These enzymes function in the monomeric form and are found in fungi, bacteria and Dictyostelium.	4.06523e-81
NZ_CP024985.1|WP_030234499.1|2234636_2235362_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	7.31709e-34
NZ_CP024985.1|WP_030234518.1|2223373_2224627_-|YncE-family-protein	gnl|CDD|225926	COG3391, COG3391, Uncharacterized conserved protein [Function unknown].	2.85781e-11
NZ_CP024985.1|WP_030234506.1|2230815_2231709_-|carbon-monoxide-dehydrogenase	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	1.22008e-56
NZ_CP024985.1|WP_030234482.1|2241676_2245441_-|S8-family-serine-peptidase	gnl|CDD|173812	cd07487, Peptidases_S8_1, Peptidase S8 family domain, uncharacterized subfamily 1. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	4.95883e-77
NZ_CP024985.1|WP_030234513.1|2226022_2227486_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.45287e-107
NZ_CP024985.1|WP_030234508.1|2230207_2230813_-|(2Fe-2S)-binding-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	2.50728e-59
NZ_CP024985.1|WP_030234521.1|2222074_2223313_-|GNAT-family-N-acetyltransferase	gnl|CDD|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	6.81485e-110
NZ_CP024985.1|WP_030234485.1|2240068_2241574_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	3.57136e-11
NZ_CP024985.1|WP_030234494.1|2236535_2237600_+|DUF2637-domain-containing-protein	gnl|CDD|378511	pfam10935, DUF2637, Protein of unknown function (DUF2637). This family of proteins has no known function.	8.25702e-15
NZ_CP024985.1|WP_030234480.1|2245642_2246620_+|hypothetical-protein	gnl|CDD|224296	COG1378, COG1378, Predicted transcriptional regulators [Transcription].	8.25796e-10
NZ_CP024985.1|WP_030234526.1|2218056_2218542_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.16423e-17
NZ_CP024985.1|WP_030234487.1|2238253_2239996_-|pyruvate-dehydrogenase	gnl|CDD|180614	PRK06546, PRK06546, pyruvate dehydrogenase; Provisional.	0
NZ_CP024985.1|WP_030234516.1|2224799_2225951_-|XdhC-family-protein	gnl|CDD|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	9.89573e-54
NZ_CP024985.1|WP_051841177.1|2235468_2236344_+|(2Fe-2S)-binding-protein	gnl|CDD|378676	pfam11575, FhuF_C, FhuF 2Fe-2S C-terminal domain. This family consists of several bacterial ferric iron reductase protein (FhuF) sequences. FhuF is involved in the reduction of ferric iron in cytoplasmic ferrioxamine B. This domain is the C-terminal domain that contains 4 conserved cysteine residues that are found to be part of a 2Fe-2S cluster.	0.000105685

Protein sequences

>NZ_CP024985.1|WP_030234506.1|2230815_2231709_-|carbon-monoxide-dehydrogenase
MDFLRPASWEEALAAKAEYPTAVPIAGGTDIMVEINFDHRRPEYLLDLNRIELLREWEVGEEVTELGASVPYTQIMENLRGTLPGLALASHTVASPQIRNRGGVGGNLGCASPAGDSHPALLAAGCSVEVESVRGSRLVPIDEFYTGVKRNALAADELIKSVHIKNATGPQQYSKVGTRNAMVIAVCGFGLALHPDTRTVRTGIASAAPTPIRAKAAEEFLNAALEEGGFWENGKVITPSIAKQFAALASAACNPIDDVRGTAKYRRHAVGILARRQLVWTWEQYRGTTGRPLEGAA
>NZ_CP024985.1|WP_030234508.1|2230207_2230813_-|(2Fe-2S)-binding-protein
MRVNFTVNGRQQEADDVWEGESLLYVLRERLGLPGSKNACEQGECGSCTVRLDGVPVCSCLVAAGQVEGRDVVTVEGLADFAKQRAEHGHGGACAAGGGCGTKGVSTDEAKRWSARPGDSRTGEGVELSNIQQAFIDAGAVQCGFCTPGLLVQADELLERNADPSDQDIREALSGNLCRCTGYEKILDAVRLAAARQGEAL
>NZ_CP024985.1|WP_030234510.1|2227805_2230205_-|xanthine-dehydrogenase-subunit-D
MANTRTTPSGTPTNVTQKHTRGGIGESTLRPDGTLKVTGEFAYSSDMWHEDMLWGQTLRSTVAHAEIVSIDVSEALAMPGVYSVLTYDDLPAEMKNYGLEIQDTPVLANGRVRHHGEPVALVAADHPETARRAAAKIKIDYRELPLVTDEASALAADAPLVHEGRDDHHAGHVPHPNIVHRQPIIRGNVEEARKRADVIVEGEYTFGMQDQAFLGPESGLAVPGEDGGVDLYVATQWLHSDLKQIAPVLGLPEEKVRMTLSGVGGAFGGREDISMQIHACLLALATNKPVKIVYNRFESFFGHVHRHPAKLHYEHGATKDGKLTHMKCRIVLDGGAYASASPAVVGNASSLSVGPYVLDDVDIEAIALYTNNPPCGAMRGFGAVQACFAYEAQMDKLAAKLGMDPVEFRQLNAMEMGTVMPTGQVVDSPAPVAELLRRVKARPLPPERQWESAGEGADVRALPGGLSNTTHGEGVVRGVGYAVGIKNVGFSEGFDDYSTARVRLEVINGEPVAMVHTAMAEVGQGGVTVHAQIARTELGVTQVTIHPADTQVGSAGSTSASRQTYMTGGAVKNTCEHVREALLEMGRRKNGSYHPAWAHAELLLEGGKVVTDGGEVLADIADILEDEAIDLELEFRHRPTVPFDLKTGQGDGHVQYTFAAHRAVVEVDTELGLVKVVELATAQDVGKALNMLSVVGQIQGGTTQGLGVAVMEEIIVDPKTAKVRNPSFTDYLIPTILDTPTIPVDVLELADPNAPYGLRGLGEAPTLSSTPAVLAAIRQATGLELNKTPIRPEALTGTL
>NZ_CP024985.1|WP_030234513.1|2226022_2227486_-|NCS2-family-permease
MTQSAVEPKTSAEEAGDGSLTPAGRSWLDRYFHITHRGSNIGNEVRGGITTFMAMAYILLLNPLILSGKDVAGDTMSQKALITATAFAAALTTLLMGFVGKVPLALAAGLSVSGVLSSQVAPQMTWPQAMGMCVMYGVVICLLVVTGLREMIMNAIPLALKHAITMGIGLFVALIGLVKAGFVGNGGEFAPPVQLGATGELSGWPVFLFCITLLAIFMLQARKVRGAILIGIVGGTVLAAILNAIVDIDPKAWKNGPPELAGSAISMPDFSLFGKVEFGGWGDVGVMTIGMIVFTLVLAGFFDAMATIIGVGTEAKLADDQGRMPGLSKALFIDGAGGAIGGIAGGSGQTVFVESATGVGEGARTGLASVVTGLFFAACLFFTPITQIVPGEVASAALVVIGAMMMQNARHVDWSDSATSIPVFLTVVIMPFTYQITAGVAAGVISYVAIKVAQGKAREVGGFMWALTGIFLIYFALHPIEAWLGVK
>NZ_CP024985.1|WP_030234516.1|2224799_2225951_-|XdhC-family-protein
MLDIAEELNRWVEQERDFAVATVVAVGGSAPRQPGAALAVDGEGTAIGSVSGGCVEGAVYELCRQALEDGETVRERFGYSDDDAFAVGLTCGGIIDILVTPVPVGSPRRQVLARALAAAAHGETAAVARIADGPEELMGRALLVQSDGSYEGGFGGHPLLDRTIAGEARAMLDAGRTGVLEIGADGRLCGEPLKVLVESSVPPPRMIVFGAIDFASALVRIGKFLGYHVTLCDARPVFATRNRFPEADEIVVDWPHRYLEGTGVDGRTVLCVLTHDAKFDVPLLELALKLPVAYVGAMGSRRTHEDRNERLRAVGVTELELARLRSPIGLDLGARSPEETALSIAAEIVANRRGGTGVSLTGAHIPIHHDPSHTVVTRIGSVA
>NZ_CP024985.1|WP_030234518.1|2223373_2224627_-|YncE-family-protein
MLHSLRTRYPVAAVLLAATAVTALAAPGRAAAPAEPLREVLFVGNNWDGTADALASTGDLARIGRINVIPDKEERLREIYLNPVRLAFFLGIRAGAGEGHDQFADDMYTTPDGSAVVVSRPSFADVVSIDVRTGRINWRFPVAGYRADHMAVSPDGTRVAVSASTANTVHVLDIATGREAGSFATGDKPHENTFSRDGRYLWNSSIGDVTSALDAPWLDWTKGDRKITVVDARTFRTVRVIDMRERLDAFGRHDLSDAVRPMSFSPDESKIYFQVSFFNGVVEYDVATDRITRIKELPVNPATSTDRTTWVNDSRHHGLSMSPDGTKLCVAGTMDDYATVVDRATLAQGPLVPADKPYWATVDGDGTACVISESGADRVTAIDFATGTKRVSVPVGDHPQRVRLGHVPADWSGPAPS
>NZ_CP024985.1|WP_030234521.1|2222074_2223313_-|GNAT-family-N-acetyltransferase
MVDIREVPEADIDRAQELAYLVFHDRPEEEARRRHHRLLSGCDRLGAYDGRALVGFMAAHPFRLSVPGADLDCPGLTFVSVAPTHRRRGVLTALMEERLRRAAAAGSPLAALWASESAIYGRFGYGAATQGVTVEIDSGRPLALRIAPDPRPLRLIEPADVPDVIAPYHEAARRTRAGRPTRSPERWEQEWLCERDEEDEELGPPRIIALGRPGEPVAGYVLYRTKPEDDTGPLPARAPGLVRVDELEADTPAVAAALWDCVASLDLTGTVRARCRPADDPLLHFAADRDQVRATAQFPALWLRLVDVAAALTARTWAAPVELVLQLADVRLPANAGRFRLKAGPGGATYEPARATPDLTLDVRELAACYLGGTRAAELVAAGLVTEHAPGAAAALDAALATGPLPHTGDEF
>NZ_CP024985.1|WP_030234522.1|2219814_2222052_+|geosmin-synthase
MTQPFQLPEFYVPYPARLNPHLEEARVHTKRWARGFGMLEGSGVWEEKDLDSHDYALLCAYTHPDCDSDALDLVTDWYVWVFFFDDHFLEMYKRSQDREGARAYLDRLAAFMPMDLAAGFPEATNPVEAGLADLWARTVPAMSTDWRERFSLSTKNLLDESMWELANINIGRVANPLEYIEMRRKVGGAPWSAGLIEYVSAEVPARVAHSRPLGVLRDAFADAVHIRNDIFSYEREVAHEGELSNAVLVLETFLGCTTQEAAEASNDLLTSRLQQFEQTALVELPQLFADHAMDPAEIAAVLAYAKGLQDWQSGGHEWHMVSSRYMNKEAKPTAPLTLPFLPSGLGTTALDVGSLFTPRSVELRRRSFTHVPFERTGPSVIPDIHMPFELSLSPHLGSAREGSVEWARRMGLIDPQPGDPGSAIWNEQKLRGYDFALCSAGIDPDATPGALLLNACWLTWGTYGDDYYPVVFARSGNLTAAKAATARLISMIPVDHAEQPLPLTALERSLADLWVRTTQDMDDRVRAEFRATLVSMLESWVWETENQIANHIPDPVDYAEMRRHTFGSHLTMYLCRLGQAGRGIPEEIYRSGTIRSLENAAADTACLINDIFSYQKEVEVEGEVHNHVLVARNFFDIGYEQALHICHDLMTQRTEEFEHIVATQLPLLYEDWKLDREARAGLDAYVVELKDWLAGILNWHRKCRRYREEDLHRPADVLHRPADGPSAAIGGSGFGMAAARIRLPA
>NZ_CP024985.1|WP_030234525.1|2218538_2219630_+|hypothetical-protein
MTRRHGTGEPGDEAVDRWFVGHGRALADALGEALDIEAGLREVLVQSRHDDAEADLEAVLDEEAGLGAILPVGASADRTDRPATSRMRTAAEGFLHSVSPMDRLAVRGDPEVAAAGRALDKAVDLTLHLDDRRLVVERAIDLAQDLVLDLSRARDLDFDIVLTLDPELDRGLFHALETARSIGALGFLTNRDREDREDRDLVRALVHAYDLNLARARGLDTARAHAQDLNRVLDLAHVLSLRVIAARSDDDEAAAASDLARVLVAIRAEQVGRAIAGVLHREPPPLDKDAALAFLHDFTTADLRAAELQGIDLGGVYWSEHGTRWPAALDLDDLRRRSVETPAGSATWVVRRGTAEFREFAVL
>NZ_CP024985.1|WP_030234526.1|2218056_2218542_+|sigma-70-family-RNA-polymerase-sigma-factor
MTDAEFSAFYRATVRPLVAFLINQGAGVHTASDIAQETMTTAYRRWNDLHAPKAWAYKVASRALVRRIAGVEEDPVGEVPEPTSLLARPDAIAEWEARHRVLPLLRSLPPRQRQVLAWTLAGFTPGDIADQLGLPNETVRANLRKARRAAAAYLETREEEL
>NZ_CP024985.1|WP_037687840.1|2233825_2234599_+|hypothetical-protein
MADTAMSGAGSTGGDDPLQRAIWRLRSRGCWTDAAALLTPHANEARAAVQRTALLVERCLFTGQGWAEAEDALRVAEAVARDDDERGAAACERGQLAYAATVLGVRDRADEARSALGRAAALLAPTSRTRPLLDFRRGLVAEHLADAPQAARPAYHRAHAGAEAHGDTLLLSFTWRHLAALALRDGELAEARKGFAESLRIREDLGFLVGTAPALAALAEAEPEPEAARLRAEARRLFHLLGGIPTWLADQLAPSPA
>NZ_CP024985.1|WP_030234499.1|2234636_2235362_-|GntR-family-transcriptional-regulator
MLGTGRDLEEDRVHEAAHAPVSKESWVPAVPAQKVLRHSVRGQVLDALRAALVDGELAPGQIYSGPALGERFGVSATPVREAMQQLALEGAVECLPNRGFRVLSGTPRALAELAEVRALLEVPVMLRLARTVPPATWEALRPAALATAEAAAAGDLPAYADADRAFHRAVLSLAGNAQLVRIAEELHRRAQWPLPGAPRVRRADLVADAAEHSALLEALVAQDLPVVESLVREHFAGSAGC
>NZ_CP024985.1|WP_051841177.1|2235468_2236344_+|(2Fe-2S)-binding-protein
MTCPAADILLPPAPAPAGSPVAEAYGRLTAAYPGLRIDERGAHEPLPSGAGWVGADELAAGGTALDDHLAWDAAQVLRDYGRAARPDVVAGFGLHRYAWPACLLITVPWFLERRVPRLPVDRVAFHRTEGRMSVRVEEFACLPGDPAAGLPGARTVPDEEALREEVRAAVAQHLGPLLEGFGPRLRRGPRARWALATDEVVEGLWYLGSLLGEERRAVAELRRLLPGGAAPYTGGADFRTLTGPGGEELTTRDRAGCCFFYTIRPEDTCTTCPRTCDTDRVTRLSAVTAAD
>NZ_CP024985.1|WP_030234494.1|2236535_2237600_+|DUF2637-domain-containing-protein
MRLTDISLDWLLPGSLLILGVLAAVAVLARGKREAEKAAADDSWERSEERRRRKEAVYGTASYVLLFCCAAVAAALSFHGLVGFGRQNLNLSGGWEYLVPFGLDGAAMFCSVLAVREASHGDAALGSRMLVWLFAGAAAWFNWVHAPRGSGHDGAPQFFAGMSLSAAVLFDRALKQTRRAALREQGLIPRPLPQIRMVRWLRAPRETFGAWSLMLLEGVRTLDEAVDEVREDKKEKENDRHRRREQHRLDRAHIKALGRQNRAFGRARARQVDMPGLAPGSGSAPVGAEPAISEADQLPLRRRPSLQAVNANGSESPDPSAPRTVDLTAEDDTQTIPRLDSLERKLKDLEQQFG
>NZ_CP024985.1|WP_030234491.1|2237684_2238122_-|ATP-binding-protein
MAREPSVGDGAARTGTTEIRRSVRRADLKAVGEVRRALRELVRHRCRAETSDVAELLVTELVSNALVHTEQGAEVSVTLVATRLRVEVRDFNARRPTPYVTSADDGTHGRGLVLVQALADAWGVDPLAPGRGKVVWFELEAPAPA
>NZ_CP024985.1|WP_030234487.1|2238253_2239996_-|pyruvate-dehydrogenase
MAKQNVAEQFVDILVRAGVRRMYGVVGDSLNPVVDAIRRTGDIEWIQVRHEETAAFAAGAEAQITGRLAACAGSCGPGNLHLINGLYDAQRSMAPVLALASHIPSSEIGLGYFQETHPDQLFRECSHYSELISNPRQMPRLLQTAVQHAIGRSGVSVVALPGDVASLPAPEKAVEHALVTARPTVRPGDGEIDKLVRLVDEADRVTLFCGSGTAGAHAEVMEFAGRVKAPVGHALRGKEWIQYDNPYDVGMSGLLGYGAAYEATHECDLLILLGTDFPYNAFLPDDVKIVQVDIRPEHLGRRSQLDLAVWGDVRETLRALNARVRAKTDRAFLDRMLKKHADALEGVVRAYTRKVEKHTPIHPEYVAAVLDELADEDAVFTVDTGMCNVWAARYLSPNGKRRIIGSFSHGSMANALPQAIGAQFTDRGRQVVSMSGDGGFSMLMGDFLTLVQYDLPVKVVLFNNSSLGMVELEMLVSGLPSYGTTNRNPDFAAIARAAGAFGVRVEKPKQLTGALRDAFRHPGPALVDVVTDPNALSIPPRISAEMVTGFALSASKIVLDGGVGRMIQMARSNLRNVPRP
>NZ_CP024985.1|WP_030234485.1|2240068_2241574_-|hypothetical-protein
MSQQGAEDWWQKLYDDADAGSEPDPGDTLDQRFRSAATLMTGPAPDVPSARRAPEPDPPWPPAPPGRVPPARPSPDTPPPRPTAAERPPAAGEPARDATPAPTVPSAPAFDGPPTPAAAPPSVGSGMPARPVPGEPAAPPPGVVPPVVQPAQPGRSDPRVAGETGYARGDVVVPPVEGADARRWPPPPPGPGRVREAADVDESGAPEAPEAPDTPESPYGPRPAVRHLGDRAPTYAPEPGALPAADPAALDFLTPDTVLEGARYGTYTLRAASLRGDSARFRGEARRDLLLTARFGGGDDGLVLVVLAGGDRAAPGAREAAAELGHSVAAAVGRSRERLADDIRAGRREALLSGLQRLTDRGYGRLRARAAELGLAEEAYTAGLRGLLLPLDPACRNRVCFGAGAGGLFRLRAGRWQDLEPDGPTPGAFRFRAAVARPGDTLLLCSGGLADPLREEGLLADELASRWSQAEPPGLAAFLADTQLRLKGYADDRTAAAVWEA
>NZ_CP024985.1|WP_030234482.1|2241676_2245441_-|S8-family-serine-peptidase
MRPISRAALGAATAAVLAVTAVGPSAAQPDDAVPGGGRPLVGSAAAGARPTAPVTVTLVTGDRILVSTDAAGRTAATAMPRANGSQPVVQTRQSGQDLYVYPEGATRALAAGTVDPQLFNVTGLIRQGYDDAHAAKLPLIAVYDGSVNVARSAPPAPRGADRSLVLGSIGAVALAADKEHAAEFWADVAAGDGRSRAAGGLKKLWLDGKVRGSLERSTKQVNAPAAWAAGFDGAGTRVAVLDTGTDLEHPDLKGRVDASKNFTDSDTDADRQGHGTHTISTVGGSGAESGGAKKGVAPGTRLLSGKVLNDQGYGLDSWIIAGMEWAVESKADVVSMSLGDPSRTACDDPLAEAAERLSRQGPLFVVAAGNSGPGNNTVSSPGCAPDVLTVGAVDRDDTTAVFSSRGPAGPGHTLKPEIAAPGVGISAANMGGRGVYAYQSMSGTSMATPHVAGAAAVLKQRHPDWSGQQLKAALVGSANSAVPGDVRETGAGRLDVKAAVDVTVTGAPAVQGGTYHWPQDRSDRTVVEVPYTNTGSRPVTLTLSLGKVTGNDGSAVRGRVARLERDTVTVPAGATVKVPLALDPAAKLERAQYGDVTGRVLATADGVHVSTPFSLYVEPETVTLRVKLIDRAGRPATGPSSLDVIGTDDATGERRFNEGAADQVYRVRPGAYFLSAFVATPDAGEGATLTDSLTYLGRPQTEVRRDTTVVLDARKAGRLTVEADRPVEARSTTLAFARSWGGVWLHAGTAMGGRTVRGYYADVEGRAEDGSFEFGSYWRAGAPVLAELKAQGGPVLHPVTASTGSDNLDGHGSARLVDAGTGTPAELAAAGAQGAVVLVKTEDGGLNTVAEDAKKAGAVAVLGHREAPGRWVPSTGFAGGALPVLGIESAEGKALLARLSAGQVTLEWRGTAKSPYAYSLAFPEQGRVQGAHAYRVRDRDLGRVDAGYHSMGVAADFIDLAGAYRPIGTAVFFGSIETVAVPGTRTEYYTAGDTAWDQTLSSSFPWGEFMTGEQRTYAKGTRTAAVWYDGVTAPVAPRDRAGKEALAAERQGNLIGFAPAMWGDGTHYAQPGSFGDIGGLQLKRDGEVIGESWYPFGVFEVPAGEGRYELVQNIEKIGPPTRTWQRSTAVRTAWGFTSKLDPSAYSQGLPVLFPRYDAPMDGLKTVAAADGQRIGLSAGGHAGYAPGALTAVKLSYAYDGEHWTQAPVLHDGGRWTAVVNHAGASGKPVSLKVEMTDAKGATVTQTVERAYEVR
>NZ_CP024985.1|WP_030234480.1|2245642_2246620_+|hypothetical-protein
MLGAIGLDEGQETAYRALVALGAAEVPDLAHRLTLPVPQTERALRHLERHGLAAQSSARPGRWVAAPPGVALGALLTQQRHELEQAELAAALLAQEYRAEAAEPAVHDLVEVVTGASAVAHRFHQLQLGAASEVCALVSGKPQVVTGMENEAEERAAVRGVAYRVVIEREVLTLPTGIREAGTALARGEEIRVTAEVPTKLVIADGTLAMVPLTARGAEPAALVVHASGLLESLRGLFEAVWRESRPLRLGTTGYAEEGDGGPDTTDLEILSLLLAGMTDASVAKHLDLGLRTVQRRVKGLMELSGVTTRLQLGWQAYERGWVAR
>NZ_CP024985.1|WP_030234478.1|2246644_2247130_+|DUF456-domain-containing-protein
MDLPQLLLVGLVLLLGVLGVMVPGVPGTWLVWAGVLWWALHERSGTAWTLLVAATALLLVVQVVKWLLPPRRLRGTAANGRMAVYAGTGAVLGFVLIPVIGSVPGFVGGIYLCERRRLGTHGEAWSSVRAVMRAVGTSVLVELVACLCVTAAWLTAALTGT

Crispr_ID: NZ_CP024985_11

• CRISPR_ID: NZ_CP024985_11
• CRISPR_location: 2934392-2934491
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_11

Consensus_repeat	Method
CGCGACGGCCGCCCCGGCCGGGTGGCTCCGCCGG	CRISPRCasFinder

spacers of NZ_CP024985_11

>11.1|2934426|32|NZ_CP024985|CRISPRCasFinder
CCGGCGTCGGCGGGCCGCACCCGCCGGGCACG

CRISPR arrays and Neighbor proteins around NZ_CP024985_11

CRISPR arrays

The CRISPR arrays of NZ_CP024985_11

>merge|NZ_CP024985|11|2934392-2934491|CRISPRCasFinder
CGCGACGGCCGCCCCGGCCGGGTGGCTCCGCCGGCCGGCGTCGGCGGGCCGCACCCGCCGGGCACGCGCGACGGCCGCCCCGGCCGGGTGGCTCCGCCGG

>NZ_CP024985|11|12|2934392-2934491|CRISPRCasFinder
CGCGACGGCCGCCCCGGCCGGGTGGCTCCGCCGG	CCGGCGTCGGCGGGCCGCACCCGCCGGGCACG
CGCGACGGCCGCCCCGGCCGGGTGGCTCCGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_078950523.1|2936980_2938033_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NZ_CP024985.1|WP_030236064.1|2944356_2945472_+|glycine-cleavage-system-aminomethyltransferase-GcvT	unknown	unknown	gnl|CDD|234742
NZ_CP024985.1|WP_030236069.1|2942428_2943163_-|enhanced-serine-sensitivity-protein-SseB	unknown	unknown	gnl|CDD|379654
NZ_CP024985.1|WP_030236104.1|2928401_2929325_+|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176191
NZ_CP024985.1|WP_030236067.1|2943243_2943900_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_030236092.1|2932640_2933495_-|thioesterase-family-protein	unknown	unknown	gnl|CDD|379298
NZ_CP024985.1|WP_030236095.1|2931329_2932493_-|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029
NZ_CP024985.1|WP_037688014.1|2934819_2935953_-|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|236898
NZ_CP024985.1|WP_030236079.1|2938155_2939916_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173871
NZ_CP024985.1|WP_030236075.1|2939957_2940950_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_CP024985.1|WP_030236115.1|2925103_2926087_-|methionine-synthase	unknown	unknown	gnl|CDD|239426
NZ_CP024985.1|WP_030236089.1|2933571_2934228_-|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl|CDD|225415
NZ_CP024985.1|WP_037688016.1|2926083_2926761_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|181298
NZ_CP024985.1|WP_030236109.1|2926841_2927186_-|DUF1330-domain-containing-protein	unknown	unknown	gnl|CDD|377765
NZ_CP024985.1|WP_030236103.1|2929395_2930529_-|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl|CDD|234664
NZ_CP024985.1|WP_030236063.1|2945584_2945968_+|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl|CDD|234918
NZ_CP024985.1|WP_037687975.1|2930597_2931326_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP024985.1|WP_078950522.1|2941631_2942372_-|enhanced-serine-sensitivity-protein-SseB	unknown	unknown	gnl|CDD|379654
NZ_CP024985.1|WP_078950524.1|2927239_2928286_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|181818
NZ_CP024985.1|WP_030236084.1|2935889_2936984_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_078950523.1|2936980_2938033_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.84814e-107
NZ_CP024985.1|WP_030236064.1|2944356_2945472_+|glycine-cleavage-system-aminomethyltransferase-GcvT	gnl|CDD|234742	PRK00389, gcvT, glycine cleavage system aminomethyltransferase GcvT.	0
NZ_CP024985.1|WP_030236069.1|2942428_2943163_-|enhanced-serine-sensitivity-protein-SseB	gnl|CDD|379654	pfam14581, SseB_C, SseB protein C-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This presumed domain is found at the C-terminus of SseB proteins.	3.91862e-26
NZ_CP024985.1|WP_030236104.1|2928401_2929325_+|NADP-dependent-oxidoreductase	gnl|CDD|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	8.96783e-130
NZ_CP024985.1|WP_030236067.1|2943243_2943900_-|ATP-binding-protein	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	0.000151061
NZ_CP024985.1|WP_030236092.1|2932640_2933495_-|thioesterase-family-protein	gnl|CDD|379298	pfam13622, 4HBT_3, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	3.11237e-44
NZ_CP024985.1|WP_030236095.1|2931329_2932493_-|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	5.17189e-164
NZ_CP024985.1|WP_037688014.1|2934819_2935953_-|dipeptide-ABC-transporter-ATP-binding-protein	gnl|CDD|236898	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional.	4.26196e-150
NZ_CP024985.1|WP_030236079.1|2938155_2939916_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.44866e-178
NZ_CP024985.1|WP_030236075.1|2939957_2940950_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.40337e-92
NZ_CP024985.1|WP_030236115.1|2925103_2926087_-|methionine-synthase	gnl|CDD|239426	cd03310, CIMS_like, CIMS - Cobalamine-independent methonine synthase, or MetE. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme catalyses the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to L-homocysteine without using an intermediate methyl carrier. The active enzyme has a dual (beta-alpha)8-barrel structure, and this model covers both the N-and C-terminal barrel, and some single-barrel sequences, mostly from Archaea. It is assumed that the homologous N-terminal barrel has evolved from the C-terminus via gene duplication and has subsequently lost binding sites, and it seems as if the two barrels forming the active enzyme may sometimes reside on different polypeptides. The C-terminal domain incorporates the Zinc ion, which binds and activates homocysteine. Side chains from both barrels contribute to the binding of the folate substrate.	4.87638e-63
NZ_CP024985.1|WP_030236089.1|2933571_2934228_-|trimeric-intracellular-cation-channel-family-protein	gnl|CDD|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	2.02744e-49
NZ_CP024985.1|WP_037688016.1|2926083_2926761_-|SDR-family-oxidoreductase	gnl|CDD|181298	PRK08219, PRK08219, SDR family oxidoreductase.	2.69943e-106
NZ_CP024985.1|WP_030236109.1|2926841_2927186_-|DUF1330-domain-containing-protein	gnl|CDD|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	3.47023e-27
NZ_CP024985.1|WP_030236103.1|2929395_2930529_-|tRNA-2-thiouridine(34)-synthase-MnmA	gnl|CDD|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP024985.1|WP_030236063.1|2945584_2945968_+|glycine-cleavage-system-protein-GcvH	gnl|CDD|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	4.47566e-56
NZ_CP024985.1|WP_037687975.1|2930597_2931326_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	2.685e-36
NZ_CP024985.1|WP_078950522.1|2941631_2942372_-|enhanced-serine-sensitivity-protein-SseB	gnl|CDD|379654	pfam14581, SseB_C, SseB protein C-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This presumed domain is found at the C-terminus of SseB proteins.	2.55086e-23
NZ_CP024985.1|WP_078950524.1|2927239_2928286_-|helix-turn-helix-domain-containing-protein	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	4.20293e-110
NZ_CP024985.1|WP_030236084.1|2935889_2936984_-|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.14679e-177

Protein sequences

>NZ_CP024985.1|WP_030236089.1|2933571_2934228_-|trimeric-intracellular-cation-channel-family-protein
MLHDLFPPDVQHALDLAGIFVFALAGALLAVRKNFDVFGIAVLALVTALGGGLFRDLVIGAVPPAAFGQLSFFVTPLVAAAIVFFLHPEVQRINRAINVCDAAGLALFCVTGTTKAYEYGLGLTASAALGLATAVGGGVLRDVLVNEVPSLLRDREMYAVPAMVGASMVAVFIGLEVLNALTTGVAIVTTFVLRLLAMRYHWRAPLAWNRRSAVAEEP
>NZ_CP024985.1|WP_030236092.1|2932640_2933495_-|thioesterase-family-protein
MSHTAAQATIGDSEFDRDTTIAPRAGEPGVYDAELSAGWTIISAVNGGYLLALVGRALSAALPHPDPFTVSAHYLTSSVPGPAVIRTQVVRAGRNLSTGQASLFQFDENGAEVERIRVLASYGDLDGLPDTVHTVAKPPVIPPYEDCLGAEAGPAPIPGSSAIVDRLRLRLDPATAGWAVGAPSGKGEMRAWFELADGRDADPLSLLLAVDALPPTAFDLGLLGWAPTVELTTHIRCRPAPGPLRVGIVTRNLAGGFLEEDAEVWDSADRLVAQSRQLARAPRP
>NZ_CP024985.1|WP_030236095.1|2931329_2932493_-|cysteine-desulfurase
MAYLDHAATTPMLPEAAAAMTAQFAVTGNASSLHAAGRRARRTVEEARESLAEALGARPSEVVFTAGGTEADNLAVKGLYWARRDADPARTRILASPVEHHAVLDAVHWLGEHEGARVEYLPVDRYGRVHPEAFREAVERAPEDVALATVMWANNEIGTVMPVGELAAIAGEFGIPLHSDAVQAFGQLDVRFGDSGLAAMTVSGHKIGGPYGIGALLLGRDQSPVPVLHGGGQERHVRSGTLDVPAVAAFAVAAVLAAERRERFAAEVGALRDELIGAVLEAVPDAVLGGDPEDRLPANAHFSFPGCEGDSLLLLLDAQGIECSTGSACTAGVAQPSHVLLATGTDPQLARGTLRFSLGHTSTREDVAAVAAAIGPAVERARTAGLS
>NZ_CP024985.1|WP_037687975.1|2930597_2931326_+|N-acetylmuramoyl-L-alanine-amidase
MAEQGTKGPAEPGKRTTGRTRRAVLFGGIGVLGAAALVGREEIGRAWWLLPGVRKPRKEGELDHAGASWTAASPANWRMADRPDDYRIDRIVVHVTQGSFASSVDAFKNPFHKASAHYIVRQDGHVEQMVRELDVAFHSGNRSMNERSVGIEHEGFVDRPQDFTDALYAASARLAADVCRRYGIPVDRTHFLGHSEVPGADHTDPGPHWDWDRYLGLVRAGLTVTAATAATAAPAAASPGPG
>NZ_CP024985.1|WP_030236103.1|2929395_2930529_-|tRNA-2-thiouridine(34)-synthase-MnmA
MTENLPRTARPLRVLAAMSGGVDSAVAAARAVEAGHDVTGVHLALSANPQSFRTGARGCCTIEDSRDARRAADVIGIPFYVWDLAERFREDVVEDFVSEYEAGRTPNPCLRCNEKIKFAALLDKALALGFDAVCTGHYATVVLNEDGTRELHRASDMAKDQSYVLGVLDEKQLAHALFPLGDTLTTKDEIRAEAEERGLAVAKKPDSHDICFIADGDTQGFLANRLGKAEGDIVDENGEKVGTHEGAFGFTIGQRKGLRIGHPAPDGKPRYVLDISPVNNTVTVGPVEALDVSALTAIRPRWCGSAAAAPGTYTAQLRAHGGETEVFAETVDGELRVTFTEPVRGVAPGQAIVLYDGTRVVGSATIATTTKAAAAAV
>NZ_CP024985.1|WP_030236104.1|2928401_2929325_+|NADP-dependent-oxidoreductase
MRAVVVSKWGGPEVLVETEAERPEPGMGEVLVRVHAAGVNPVDWKTRESGGLIPWGPVPAVGWDVSGTVEAVGPGVTLYRAGDEVYGMPRFPQQAGAYAEYVTAPARHLARKPASLSHVEAAALPLAALTAWQALVDTAGVSAGQRVLVHAAAGGVGHLAVQIAKARGAYVIGTASAGKHELLRALGADEVIDYRTTDFEDAVADVDVVVDAIGGDHGERSLKVLRPGGHLVTLPGPDGLPADPGGVHASWVLVEPDLKGLEEITALVEGGLLKPLIDTVLPLEQAAKAHEIGERGRTTGKIVLTVA
>NZ_CP024985.1|WP_078950524.1|2927239_2928286_-|helix-turn-helix-domain-containing-protein
MHRVAVLALEGVPPFELGIPSRVFGNAQDDAGNPLYELTVCTADGRPVTSDAGFTIGVSAGPEALAAADTVIIPPTHAMDELARGEALPQALVDALAAIRPGTRLVSLCTGSYVLAAAGLLDGRPATTHWLHAPEFQRGFPRVRLDEEVLFVDDGDILTSAGVAAGVDLCLYMIRQDHGTAVANRAARLCVVPPWRDGGQAQYIDRPVPAPTVATTTATRAWALERLAEPITLAELAAHARMSLRTFTRRFRDEVGMTPVQWLTGQRLEIARQLLESSDLPVDLVAHRSGFGSANSLRQHMRTAFGVSPIAYRRTFGPHTARPEAVAQTAPETTPEMTPEVIAPAAAR
>NZ_CP024985.1|WP_030236109.1|2926841_2927186_-|DUF1330-domain-containing-protein
MTAYAIGHIRPETMNEDVLRYIEEIQSTMDPFEGRFLVHGNPVEVLEGSFPGDLVIIAFPDIERARAWYASPAYQEILPLRSRHIPGDILLVEGVPAGYDATRTAAALRGSAGL
>NZ_CP024985.1|WP_037688016.1|2926083_2926761_-|SDR-family-oxidoreductase
MITGAGSGIGAAVAARLHARGDDLVLLARDAARARQLVERYPGARTLVGDLADPDRLSWAFSKQPVPERIDSLLHIAGIVDLGPVGDLRPKTWHQQLNVNLIAPAEVTRLLLPTLRASKATVVFVNSGAGLTAHADWSAYAASKHGLKALADSLRAEEKPNGIRVTSVYPGRTASPMQAKVHSQEGKEYDPARWIDPESVATTIVMAVDLPRDAEVNDLTVRPGR
>NZ_CP024985.1|WP_030236115.1|2925103_2926087_-|methionine-synthase
MTASATGVGSLPGGDAREAAKTVTGSFEEFPYLAELPARGPGADMIGRSLGLLVDLYAHVEPSGWRISDRPGRDTRRARSWLGEDLDALEEFTQGYTGKLKVQAVGPWTLAAALELHGGEALLQDPGACRDLAGSLAEGLRGHLADVRKRIPGAEIVLQYDEPSLTAVLLGRVRSASGYRTYRAVDRQVVESALRELFAVHDGEVIVHSCAPEVPFGLLRRAGATGVSFDFSLLTEREDDAIGEAVEDGVKLFAGVVPGTDGPLSDPGGSVMGVRKLWRRLGLAPGTLAESVVVTPSCGLAGASPAYARAVQAHCVRAARSLADNPE
>NZ_CP024985.1|WP_037688014.1|2934819_2935953_-|dipeptide-ABC-transporter-ATP-binding-protein
MPHVAGGADPDLDRRDCAEAVSENPETNTEDALLKVTGLVKHFPINKGLLRRQAGAVKAVDGIDFEVRRGETLGIVGESGCGKSTMGRLITRLLEPTDGRIEFEGKDITHLGVAGMRPLRRDVQMIFQDPYGSLNPRHTVGTIVGAPFRLQKVTPEGGLKAEVQRLLSLVGLNPEHFNRYPHEFSGGQRQRIGIARALALKPKLVVADEPVSALDVSIQAQVVNLLDDLQEELGLTYVIIAHDLSVIRHVSDRIAVMYLGKIVELADRKSLYEAPMHPYTTALMSAVPVPDPRRRGAKSGRILLKGDVPSPISPPAGCRFHTRCWKATEMCTKVDPPLVALKTGHQVACHHPENAPDQAPGDPALPGATEAVATATE
>NZ_CP024985.1|WP_030236084.1|2935889_2936984_-|ABC-transporter-ATP-binding-protein
MTKTVSDEPAFVPEQGGPRDAAPFLSVRDLRVHFPTDDGLVKSVDGLSFDLERGKTLGIVGESGSGKSVTSLAIMGLHRTGNARSRPHISGEVVLDGEDLVAADADRVRRLRGRKMAMVFQDPLSAMHPYYSVGKQIVEAYRTHHDVDKKTARTRAVEMLDRVGIPEPHRRVDAYPHEFSGGMRQRAMIAMALVNNPELLIADEPTTALDVTVQAQILDLIRDLQKEFGSAVIMITHDLGVVAEMADDILVMYGGRCVERGTAEKVFYGPRHPYTWGLLGSMPRIDRDQTERLIPVKGSPPSLINIPSGCAFNPRCPYADVPKGGITRTQRPELTEDDSRHWSACHMSQEERTRIWTEEIAPKL
>NZ_CP024985.1|WP_078950523.1|2936980_2938033_-|ABC-transporter-permease
MPSPRGTAAARPGRPTAVLVYLIRRLFNVAATLLVVSAVTFGIFFAVPKLTGSDPALMYAGRETSETALQGIRVKMGFDKPISEQYWVFLKGIFVGRDYDAGTEVTHCAAPCFGYSFKSEAPVWQTMLDRMPVTLSLALGAAVIWVLAGVATGVVSALKRRTAIDRTVMVGALAGVSLPIFFTGMVAPAVFVYSLGWLDVSNYKPLTEDPLAWLNSMILPWVTLAFLFAATYARITRATMLEVLGEDYIRTARAKGLKEGVVIRKHALRSTLTPIVTMFGLDLGGLLGGAVLTETTFNFQGLGTAAVAAIGQGDLPVIMGVTLLAALFVVMANLIVDLLYAVIDPRVRLT
>NZ_CP024985.1|WP_030236079.1|2938155_2939916_-|ABC-transporter-substrate-binding-protein
MIRRKQALAITAVIAALSLTAACGGNDKKADGSDDKGDKGYSGATASLVNASDAKGGELKLWSPQDVDFLDPARAYYGFVWNLQRLYIRQLYAYDSKPGAAGTKLVPDLAAGEPVLSNDGKTYTVKIKDGVKFEDGSPITAKDFKYGIERVFAQDVLSGGPTYLIDLLDQGQKYPGPYKDTDPNKMGLKSVETPDDHTIVFNLASANSDFKYLLAMPSSSPVPAGKDEGASYTNKPVATGPYKVESFASGKGATFVRNENWDQATDTIRKGLPDKVTFTVTTNPDDMDQRLLSGDIDLAVDGTGVQQAAKNKILKDANLKKNADNPYTGYIRYFAFPQTVAPFDNIECRKAVIYAADPKSLQNARGGPTSGDLGANMLPPGIPGSDKKYDPFNLTSGKPQLDKAKAALKACGKPDGFETTIAVRNNRAPEVKSAESLQAALAKIGVKATIDQYDGKLSSSTIGSPENVKKKNYGIIVMGWGADYNSGSGFLQPLVDGSFILPNGNNNYTEVNDPEINGLFKTAAAAATPEAAAPFYGQINQKVMEKALYLPINFDKALIYHNPRLTNVYFNDSMGRIDLAVLGVGK
>NZ_CP024985.1|WP_030236075.1|2939957_2940950_-|ABC-transporter-permease
MTAPQHDTSAETPAPVSVADVPAKAIEGRSPGRIAWMRLKRDKVALTGGVVVILLILVAVFAPLIVGLLGHDPNEFHEDMIDPDLGTPLGSFGGISSDFLLGVEPTNGRDVFSRIVYGARISLVVAFLAAFVSVVLGSLLGALAGFLGGWVDAVISRVMDLLLAFPQLLFTIALVSVVPNSLWGFEGSGVRMGVLIVVIGFFGWPYIGRIVRGQTISLREREYVEAARSLGAGRGYILIKELLPNLIAPILVYSTLIIPTNILTEAALSFLGAGVKPPTASWGKMLSDAVPIYQDDPMYMVVPGITIFITVLAFNLFGDGLRDALDPKGS
>NZ_CP024985.1|WP_078950522.1|2941631_2942372_-|enhanced-serine-sensitivity-protein-SseB
MSASGTAAAGQVEHMLRQVTPGRYESYESFLHALAEGRLWMLLWQGQPGSPDAQYGGMEVEGLGYAPCVTSPQELAASGWNRGYEVVTGRDIARALYPDRWGLWVNPHAPGGGLGVPWADLRRVATGLDRMPAGPLRLSEPALELPQFYGLLTQHAHRTPAVRSLRRAWVQPALGTAYLAVGLDLYDASAPALESVREMMRQSVGAVPEGVPVCTVALADEHDPVAMWLRAQTRPFYDREGQAAAY
>NZ_CP024985.1|WP_030236069.1|2942428_2943163_-|enhanced-serine-sensitivity-protein-SseB
MQGSGWPANELEQVLGAALGRPDAGPRILEALGRSQVWVPLPHGGSPDHAALDLPTMLIGGEAYVPVYSSEAQFRHGAGPAMDFAIAPAVEFARGLPPQLGIAVNPEGAVGVPLPPAAVAELCRAGRTPLDGPATGGRVRLFEPDWQEDPVDFLAAAAEEFRATGVVTAAHRCLASVEAGPPQLYVGVRLVGQDLGLRDAPLEALGRALARVPAPWPVQLILLDAAEDPVTDWIRERVRPFYLP
>NZ_CP024985.1|WP_030236067.1|2943243_2943900_-|ATP-binding-protein
MTVRRFGVLAATGTVDGVPAQRSPRPRPAGRVRDLRGAAVAGPRRLGFPAGDIVVVSGLPGGGKSTLIKRAAEDGGIDSQDARERWERRMPGALPYAVYRPLVRAAHYWGLWRRLRTGDSVVVHDCGTQMWVRGMLAAAARRRGRSLHLLLLDTTAEEARSGQEARGRRVSAYAFARHRGAVGRLLRDAEAGRLPAGCDSAVILDRRSAAAVTRICFF
>NZ_CP024985.1|WP_030236064.1|2944356_2945472_+|glycine-cleavage-system-aminomethyltransferase-GcvT
MSTAPRLTALDALHRSLGATMTDFAGWDMPLRYASERDEHNAVRTKAGLFDLSHMGEITLTGPEAVKVLDYALVGNISTVGVGRARYTHICQEDGGILDDLIVYRLGETEFMVVANASNAQVVLDALTERADGFEAEVRDDRDAYALIAVQGPESPGILKSLTDADLDGLKYYAGLPGTVAGVPALIARTGYTGEDGFELFVSPEHAVELWQALTEAGEGVGLVPAGLSCRDTLRLEAGMPLYGHELTTSLTPFDAGLGRVVKFEKEGDFVGRAALEAAAERAATNPPRKLVGLIAEGRRVPRAGFPVVADGQVIGEVTSGAPSPTLGKPIAMAYVDAAHAAPGTSGVGVDIRGTHEAYEVVALPFYKRQK
>NZ_CP024985.1|WP_030236063.1|2945584_2945968_+|glycine-cleavage-system-protein-GcvH
MSNPQQLRYTKEHEWLSDAVDGVATVGITEFAANALGDVVYAQLPAVGDTVTEGETCGELESTKSVSDLYSPVSGEVVEANQDVVDDPALVNTAPFEGGWLFKVRLSEEPKDVLSADEYAALTHSDN

Crispr_ID: NZ_CP024985_12

• CRISPR_ID: NZ_CP024985_12
• CRISPR_location: 3094061-3094159
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_12

Consensus_repeat	Method
GCGCGGGGGTCCGGGGGCTGGCCCCCGGCAG	CRISPRCasFinder

spacers of NZ_CP024985_12

>12.1|3094092|37|NZ_CP024985|CRISPRCasFinder
GCGGCCCGCACGAAATCCAGCCCCGCCGGCGTTTGAA

CRISPR arrays and Neighbor proteins around NZ_CP024985_12

CRISPR arrays

The CRISPR arrays of NZ_CP024985_12

>merge|NZ_CP024985|12|3094061-3094159|CRISPRCasFinder
GCGCGGGGGTCCGGGGGCTGGCCCCCGGCAGGCGGCCCGCACGAAATCCAGCCCCGCCGGCGTTTGAAGCGCGGGGGTGCGGGGGCTGGCCCCCGGCAG

>NZ_CP024985|12|13|3094061-3094159|CRISPRCasFinder
GCGCGGGGGTCCGGGGGCTGGCCCCCGGCAG	GCGGCCCGCACGAAATCCAGCCCCGCCGGCGTTTGAA
GCGCGGGGGTGCGGGGGCTGGCCCCCGGCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030235729.1|3086661_3087066_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030235702.1|3092568_3093801_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP024985.1|WP_030232520.1|3094468_3095182_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP024985.1|WP_030232517.1|3094188_3094458_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740715.1|3100778_3101204_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660873.1|3091825_3092572_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037687989.1|3083883_3085101_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP024985.1|WP_030235712.1|3090100_3090901_-|NERD-domain-containing-protein	unknown	unknown	gnl|CDD|377990
NZ_CP024985.1|WP_030235723.1|3088005_3088890_-|ATP-dependent-DNA-ligase	unknown	unknown	gnl|CDD|240133
NZ_CP024985.1|WP_030235726.1|3087118_3088006_-|DNA-ligase	unknown	unknown	gnl|CDD|185714
NZ_CP024985.1|WP_030232522.1|3095205_3096135_-|diiron-oxygenase	unknown	unknown	gnl|CDD|378680
NZ_CP024985.1|WP_030235732.1|3085376_3086366_+|xanthine-dehydrogenase	unknown	unknown	gnl|CDD|379212
NZ_CP024985.1|WP_030232527.1|3097455_3098916_-|penicillin-binding-protein	unknown	unknown	gnl|CDD|274573
NZ_CP024985.1|WP_030235718.1|3088921_3090076_+|Ku-protein	unknown	unknown	gnl|CDD|238408
NZ_CP024985.1|WP_030232533.1|3100389_3100779_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030235708.1|3091088_3091727_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030232525.1|3096295_3097420_+|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|153097
NZ_CP024985.1|WP_030232530.1|3098912_3100292_-|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl|CDD|223843
NZ_CP024985.1|WP_030225679.1|3103472_3104732_-|oxygenase	unknown	unknown	gnl|CDD|380046
NZ_CP024985.1|WP_030225676.1|3102387_3103521_+|C40-family-peptidase	unknown	unknown	gnl|CDD|366353

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030235702.1|3092568_3093801_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.20898e-34
NZ_CP024985.1|WP_030235732.1|3085376_3086366_+|xanthine-dehydrogenase	gnl|CDD|379212	pfam13478, XdhC_C, XdhC Rossmann domain. This entry is the rossmann domain found in the Xanthine dehydrogenase accessory protein.	1.5885e-35
NZ_CP024985.1|WP_030235726.1|3087118_3088006_-|DNA-ligase	gnl|CDD|185714	cd07905, Adenylation_DNA_ligase_LigC, Adenylation domain of Mycobacterium tuberculosis LigC-like ATP-dependent DNA ligases. Bacterial DNA ligases are divided into two broad classes: NAD-dependent and ATP-dependent. All bacterial species have a NAD-dependent DNA ligase (LigA). Some bacterial genomes contain multiple genes for DNA ligases that are predicted to use ATP as their cofactor, including Mycobacterium tuberculosis LigB, LigC, and LigD. This group is composed of ATP-dependent DNA ligases similar to Mycobacterium tuberculosis LigC. ATP-dependent polynucleotide ligases catalyze phosphodiester bond formation using nicked nucleic acid substrates with the high energy nucleotide of ATP as a cofactor in a three step reaction mechanism. DNA ligases play a vital role in the diverse processes of DNA replication, recombination and repair. Members of this group contain adenylation and C-terminal oligonucleotide/oligosaccharide binding (OB)-fold domains, comprising a catalytic core unit that is common to all members of the ATP-dependent DNA ligase family. The adenylation domain binds ATP and contains many of the active-site residues. The common catalytic core unit comprises six conserved sequence motifs (I, III, IIIa, IV, V and VI) that define this family of related nucleotidyltransferases.	1.12996e-67
NZ_CP024985.1|WP_037687989.1|3083883_3085101_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.10082e-62
NZ_CP024985.1|WP_030235712.1|3090100_3090901_-|NERD-domain-containing-protein	gnl|CDD|377990	pfam08378, NERD, Nuclease-related domain. The nuclease-related domain (NERD) is found in a range of bacterial as well as archaeal and plant proteins. It has distant similarity to endonucleases (hence its name) and its predicted secondary structure is helix - sheet - sheet - sheet - sheet - weak sheet/long loop - helix - sheet - sheet. The majority of NERD-containing proteins are single-domain, but in several cases proteins containing NERD have additional domains which in 75% of cases are involved in DNA processing.	4.5385e-05
NZ_CP024985.1|WP_030235723.1|3088005_3088890_-|ATP-dependent-DNA-ligase	gnl|CDD|240133	cd04863, MtLigD_Pol_like, MtLigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Mycobacterium tuberculosis (Mt)LigD. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for non-homologous end joining (NHEJ)-mediated repair of DNA double-strand breaks (DSB). NHEJ-mediated DNA DSB repair is error-prone. MtLigD is monomeric and contains an N-terminal Pol domain, a central phosphoesterase module, and a C-terminal ligase domain. It has been suggested that LigD Pol contributes to NHEJ-mediated DNA DSB repair in vivo, by filling in short 5'-overhangs with ribonucleotides; the filled in termini would then be sealed by the associated LigD ligase domain, resulting in short stretches of RNA incorporated into the genomic DNA. The MtLigD Pol domain is stimulated by manganese, is error-prone, and prefers adding rNTPs to dNTPs in vitro. The MtLigD Pol domain has been shown to prefer DNA gapped substrates containing a 5'-phosphate group at the gap.	4.99751e-106
NZ_CP024985.1|WP_030232520.1|3094468_3095182_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.05762e-11
NZ_CP024985.1|WP_030232522.1|3095205_3096135_-|diiron-oxygenase	gnl|CDD|378680	pfam11583, AurF, P-aminobenzoate N-oxygenase AurF. This family is a metalloenzyme which is involved in the biosynthesis of antibiotic aureothin by catalyzing the formation of p-nitrobenzoic acid from p-aminobenzoic acid. AurF is a non-heme di-iron monooxygenase which creates nitroarenes via the sequential oxidation of aminoarenes.	8.23177e-108
NZ_CP024985.1|WP_030232527.1|3097455_3098916_-|penicillin-binding-protein	gnl|CDD|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	7.77437e-81
NZ_CP024985.1|WP_030235718.1|3088921_3090076_+|Ku-protein	gnl|CDD|238408	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku homologs are predicted to form homodimers. It is proposed that the Ku homologs are functionally associated with ATP-dependent DNA ligase and the eukaryotic-type primase, probably as components of a double-strand break repair system.	7.11989e-107
NZ_CP024985.1|WP_030232525.1|3096295_3097420_+|ferritin-like-domain-containing-protein	gnl|CDD|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	1.10401e-14
NZ_CP024985.1|WP_030232530.1|3098912_3100292_-|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl|CDD|223843	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning].	2.80488e-75
NZ_CP024985.1|WP_030225679.1|3103472_3104732_-|oxygenase	gnl|CDD|380046	pfam17885, Smoa_sbd, Styrene monooxygenase A putative substrate binding domain. This domain is found in the 46 kDa FAD-specific styrene epoxidase (SMOA) protein, comprises a part of the styrene monooxygenase (SMO) two-component flavoprotein monooxygenase enzyme. Structural analysis indicates that SMOA monomer comprises two globular domains spanned by a long alpha-helix. This domain contains a putative substrate binding site.	7.13375e-57
NZ_CP024985.1|WP_030225676.1|3102387_3103521_+|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.39036e-23

Protein sequences

>NZ_CP024985.1|WP_030235702.1|3092568_3093801_+|HAMP-domain-containing-histidine-kinase
MRRVLPAWTATLTWKSACFIVVMCCSLAAVLGVLVHAEVTRQTVAAAREKALAKLHDAAAAYEAGEALPPDSGIDPAGLPPELRALAVSGQRATVVADRLGQPVMWAAAPADGRALATAIEYGQSARTIRGLDNAIIGSSVLAIGGTLLVGAFAVTRVTRRLHQTATVARRITGGDLDARVGDRRTTDPSRHQDEVSTVAGALDTMAGTLQAKLLSEQRFTADVAHELRTPLTGLQAASELLPEGRPTQLVRERVRTMRQLTEDLLEISRLDSGSERVDTDLHQLARLARRVVRASGTDTEVVVVRDAHVETDRRRLERVLGNLVANAHKHGRGPVVVTVDGPVVTVRDHGDGYPEYLLAHGPQRFRSGGKGKGHGLGLTIAVGQAEAIGAGLEFRGAEGGGALAVLRLP
>NZ_CP024985.1|WP_100660873.1|3091825_3092572_+|hypothetical-protein
MGRTQSTGRPSTVRIPPSRAGAALLGLLLPLPLLAGCGNTGGLAAAGPTPTASGPVHLWPERAGAEVPPADPGGAPPEYVQGLPRVVGQNVHDVDPVALVQAELRARPGLVTGPDGMPAETAAAIMACGTAGEDPGRCPVRRPYYRDLTGNGKDEVVVGIEFPDRMMSVRVYTADPDGRLNRIMATTQTVVAVELAGRDVILRVPSGNPGYELITAWSWDGKQRTMLPAREQIVRVPAPPRPSAGGAS
>NZ_CP024985.1|WP_030235708.1|3091088_3091727_+|hypothetical-protein
MSTVSRRSTVRAAAVTACVAGLLALPAATAFAEGRPASGAQRTLVKSIFLADGRSTAKVYRLAKDAYQADILRSGTTVATLTSRDGSTGFGGSGELHAALRPDGRLSSWVGETRPQDGSHAVAGDGHKTGTRHGSGGGDGRVLPASTEDGGGRGATGTGSGTGTGTAQALRLHSLADGPGDGVLLLAAGGGIAAVGAAGLGFAMLRRGRTDG
>NZ_CP024985.1|WP_030235712.1|3090100_3090901_-|NERD-domain-containing-protein
MSGLKVLPSGRPGRGRLYVSGSDGHAVAWYDRRTNRISVLEDDQRAAVLAALRPYLSGDWTIGPPPVPTPAELLRLTLPPDLDLAPNRPGETLLGELAYGSPGSRARHRMRQELQARQRIGAELDALEEEDWRALHDVPLPGLGMLDHLLVGPAGVFAVRTVAGRRQRAQVGDLLLTVGRAEPRPDPRWIRRAAARTARALTAQVTPVLALADASRIDVAPTVRDVLVLQSATAAAVLTAAPATLKLPDVEALFTLARTRSTWSAP
>NZ_CP024985.1|WP_030235718.1|3088921_3090076_+|Ku-protein
MRSIWNGAISFGLVSIPIKLVNATESHSISFRQIHVSDGGRVRYRKVCELDGEEVPAAEIGKGYEEADGSIVPITDEDLARLPIPTAKTIEIVSFVPAEEIDPLQMDAAYYLAANGATAAKPYTLLREALKRSRKVAIAKYALRGRERLGMLRVVDDVIAMHGLLWPDEIRQPEGVAPEASVTVREAELDLADALMATLGEVEIASLHDDYREAVEAMLAAKTGEGFEPAEAVVEPAGGQVIDLMAALESSVRAAKASRAGGSGESAESAAEAEVTPIRGRRTPAASAPAPKAVGGKKSTASTGTAKKTAAAKKTAAGGKKSTATAKGAAGTKSGAGARAGARSTKSASAAGAKSAGTGRASAAGATAGAGAAKKAAPRKRSSA
>NZ_CP024985.1|WP_030235723.1|3088005_3088890_-|ATP-dependent-DNA-ligase
MTPITMVEGRRIALSNLDKVLYPRTGFTKGEVLHYYATVADSLLAHIRDRPVSFLRYPDGPDGQLFFTKNPPPGTPAWVRTTPVPRSEDAGAEQVVVGDLPTLMWAANLVVEFHTPQWTAGRPAVADRIVFDLDPGPPATVVECCAAARWLRGRLAADGLDAYAKTSGSKGLHLAVPIEPTPSARVSAYAKTLAQEAEAALPGLVLHRMARALRPGKVFVDHSQNAAAKTTAAPYTLRARELPTVSAPVTWEEVEGCRTAADLVFLADDMAPRLARDGDLLAPLTDPARAGRLP
>NZ_CP024985.1|WP_030235726.1|3087118_3088006_-|DNA-ligase
MRVALAAAVRTLPRGAGLAYEPKFDGHRLVVVRTAQDVVLQARSGRIVTAAFPDLAAAARQLPAGTVLDGEVVVWHAGRTDFALVQRRAAAASAARAAVLAQRLPASYAAFDVLELAGLDVRTRPYERRRALLVDLLLPLGPPLQPVPMTTDPELAETWYATLPASGIEGLVVKRLDESYPAGRRSWRKLRHTDVADAAVIGFTGTPRCPLALVLVLPGDDEAPVVSSPLPAGLRTEMAAAVATLGEAAPAAATVTAIGLGEVPFRLLDPPLAAEVRRSSARHPPPEVLRLRTGL
>NZ_CP024985.1|WP_030235729.1|3086661_3087066_+|hypothetical-protein
MNTTLIPLAADATLGQIAWFLVVGLGVVGVLLGGFALGRRVRDHEPPPPTPESQPHLPDGGAVYEVREERDYVEIPEGGLRPHEMQGYGNFGSRTHSHPDDARAERESGYEVPKGPGPHVQPGAPPNAGRGAHA
>NZ_CP024985.1|WP_030235732.1|3085376_3086366_+|xanthine-dehydrogenase
MRELAETARQWVAEGRVAFLARPVTEQGFGPRDPAGALLVDVRGECVGALYRGVFDAELVAEAAALGGGAGAEGARVCELSVGAGEAVEARLTCGGQAEVLLQPLAAIPAEWWELLGTGAGVALVTRLNEDADRAESRVVRADGTAGDDAERRAGELLGTRRPGRDALYGGSGLVLVEAYPSAPHVVIGGAGELAEVIAAQAALLGWEAVAVESAAEAEKVLSAHRDAACLVLLSHEPDFDVPALRTALALGIPYVGALGSRRTTARRREGLLAAGVREAELARVHGPIGLDLGAKTPAETALAICAEILGVLGGREAQGLRDSDGPLR
>NZ_CP024985.1|WP_037687989.1|3083883_3085101_-|MFS-transporter
MRRTFQSLSVRNFRLFVLGQLLSVTCTWMMVIAQDWLVLELSGDSGTALGVVTALQFTPVLLLTLYGGRLADRHSKRSLLMLANSASGVLALALGLWILLGEVRLWHIWLFALALGTVNAVEAPTRISFVGEMVGGELLPNASAMSAAYFNVARVVGPAIAGFLIARLDVAAVVLINAVSYLGTVASVALMRPAELHVPAERPARPRVADGLRYVGRRPDLVLPLVLLGVVGLAGFNFQLTLPLMAKTEFHTDSTAFGLLSSSLAAGSLLAAFATTARRGRPSALVVTGSALAFGATEALAGLAPTLTTACLLLTLTGFTMMYFAQASNHRVQLGTDPAYRGRVMALYTVIFQGGTPLGALLTGWLAEHWGPRWALSTGGLITLTTATLTLTLSRRPAPPTPEAR
>NZ_CP024985.1|WP_030232517.1|3094188_3094458_-|hypothetical-protein
MRSEPTPFEGGPMDGRVLPILLGPTGHPPKWYEIPVPAPDGGLPTVLLYERVPAGYSKRLGLQKGWKYAFTPTGRKPKPRWPWTKPPKP
>NZ_CP024985.1|WP_030232520.1|3094468_3095182_-|TetR/AcrR-family-transcriptional-regulator
MTVRAYRRLSVEERRAQLLDAALSLFAHRAPEEVSLDDVAEAAGVSRPLVYRYFPGGKQQLYEAALRSAADVLELCFAEPQQGPLTQRLSRALDRYLAFVDEHHTGFSALLQGGSVVETSRTTATVDGIRRAAADQILVHLGVPTPGPRLRMMVRTWITAVEAASLIWIDEGRQPEAGELRDWLLDQFIALLTATAATDPETASAARAALALESADGPVGVLARRVIPVVSEAAHLL
>NZ_CP024985.1|WP_030232522.1|3095205_3096135_-|diiron-oxygenase
MTTVTERAALRDALGLLKDREQVAERLLESSAKHSFDPDRELDWDAPPIEGKYYWPPELLSLYDTPLWKKMGEEQRIDLSRHEAAALGSLGIWFEIILMQLLVRHIYDKSLTSNHVRYALTEIADECRHSMMFARMIRESGTPAYPVSRVNHNLARILKTVSTTPGSFACTLLGEEILDWMQRLTFPDERIQPLVRGVTRIHVIEEARHVRYAREELRRQMLTAPRWEQELTRISCGEAARVFSLAFVNPQVYDNIGLDRREAVAQVKASGHRREVMQTGAKRLTDFLDDIGVLRGVGRRLWKSSGLLA
>NZ_CP024985.1|WP_030232525.1|3096295_3097420_+|ferritin-like-domain-containing-protein
MSTHELYTTAPGEGVWQVPATGSARFGWEYDGGRERLLALYRKGKDKQWDGAKRIDWGIEVDPYDPLGTPDEVLTLYGTRHWDRMTDRDKGELRRHYSAWNFSQFLHGEQGAMVCAARIVESVPDLDAKFYSATQTMDEARHAEIFGRFLHEKVGMLYPINDSLQGLLGDTLRDSRWDMPYLGMQVLIEGLALAAFGMIRDTTDKPLPKQILAYVMQDEARHVAFGRMALRDYYKQLTDAELREREEFVIEGCYLMRDRLRGVEVLENFGIPRREAEEYSEQSEFLHLFRKLLFSRIVPCVKDIGLWGERLQKAYLDMGVFDMGDANLDLLMSQDEELAESLDRERFAAEEQERVAEVAAAVREGAKEAEGAAG
>NZ_CP024985.1|WP_030232527.1|3097455_3098916_-|penicillin-binding-protein
MIRYIRWCAWFCALLLLALLVNVARVQVWEAAAYGANPANKRPAVQRYAEPRGEILVDGKPVTGSRDSGQLLRYERTYADGPLYAPVTGFSSQTYGTSFVERAEDAVLSGTDPGLSAFPLWYELSRGRPGGGNAVTTLRAAVQRAAYRGLGGKRGAVAAVEPATGRILALVSSPSYDPGLLSGTGAKVKAAWRRLNADPAKPMLNRALRETYPPGSTFKIVTAAAALDSGVVTDVDAPTETPDPYPLPGTSTLLPNAGTGCQDASMAEAVQFSCNTVMAKIGVRVGLRRMAEAADRFGFNDDGLRVPSWVSRSNFDTDMSPDQLALSSIGQFNTKATPLQMAMVAAAVANGGEIKTPYLVDRTTRGDGSQVRRTDQRTLGRAMSPATALRMQELMVKVVENGTGRNAAIKDAQVGGKTGTAQHGVGNAGTPYAWFISWARAKGAPQPAVAVAVVVEDASAVRGDISGNGAAAPIARAVMEAALSTR
>NZ_CP024985.1|WP_030232530.1|3098912_3100292_-|FtsW/RodA/SpoVE-family-cell-cycle-protein
MTALTARVTEPAPPPPPDARTPKGRGIELTLLAGAVLISVLGHLYVGLADTGHLPRPGGRYAGGLAAAALLAHLAVRFRASYADPLLLPIAVLLNGLGLVLIQRLDLATPGESGAGDQLRWSALGVVLFVLVVAGLRDHRALQKYAYLSVAAALALMLVPVLFPAVNGAHIWIRFAGLSFQPGEFAKILLAVFFAAYLAANRTALALTGRRIFWKLRLLPGRVLGPILAIWLLSVGVLVLERDLGTSLLFFGLFVIMLFTATGRIGWIAIGLVLAALGAYAVGTLEPHVHGRVDDWLNPFASIERGEGPGQLAQSLFSFAAGGLLGAGLGHGQSFLIGFAAKSDFVLATAGEELGLVGLTAILLLYGLLVSRGFRAGLALRDPFGRLLATGLASIIALQVFVIAGGVTGLIPLTGMAMPFLAQGGSSVVTNWIIVALLVRLSDNARRPRPAESAGEGAG
>NZ_CP024985.1|WP_030232533.1|3100389_3100779_+|hypothetical-protein
MGPVEFIVLAFPEEQLRVPAVEAVMGLRKTGVVRLIDGLVTTKTAGGEVMAAEFDEFVELRGLLAGRDVARLIGPEDVREAAELLDRGSCALLLVVEHVWAQDAAVAVRAAGGRIVGSVRIPADRVEVA
>NZ_CP024985.1|WP_158740715.1|3100778_3101204_+|hypothetical-protein
MFIRPVGVTVSPALRPPGHPLLRGLLRRAAGAAEWATAEEGVAEESVAEELEEALEEGVRREYEVEAGTEAEREGPGAPEGPGAPEGGDGGEPPTEAEPPTHPPVTGPTLVAELTQLSDLARQGLLTPEEFTLAKGRLLRG
>NZ_CP024985.1|WP_030225676.1|3102387_3103521_+|C40-family-peptidase
MTKRLLRLACLAAVLVAAAGPPPVARAEPVGELLTRLQGLYQRAEEASEAYNATEVALKAGQDEERRLTAELGRARTALGAEKATAGRLAREQYQGTLGLSPYLRMLLSGDPQQAVDQRRIAARQGARQAGVVARLERGEQRADALAAAARKALDTQQGLVAERRKQHEEVTGRLKDVERLLAALTPEELSGLDRREAAVTAGAQRELVDSGRLPARTGTPTAAGGAALRYATAQIGKPYVWGAEGPGSFDCSGLTSKAWEHAGRSIPRTSQEQWAQLPRVPLDRLRPGDLVVYFPKATHVALYIGDGKVIQAPRPGATVKVSPIAANPLLGAVRPDPEGVPLAEFTPPPLPEGATAGDDTGYSAGTGDSDEDTSAR
>NZ_CP024985.1|WP_030225679.1|3103472_3104732_-|oxygenase
MRRILVVGAGQSGLQLALGLQAKGYEVTLMSNRTADEIRTGRVMSTQCMFDSALQHERDLQLNFWERQAPRIEGVGVSVAAPDATRPIDWLGRLKGYAQSVDQRVKMAGWLDTFTQRGGQLVIHGASVADLDFFSRTYDLVLVAAGKGELVSMFERNATRSPYDAPQRALAVSYVHGLGPRPEHPETEAVRCNLVPGVGELFVMPTLTTSGRADILFWEGLPGGPLDVFRGVNDPGEHLALTLELMEKYTPWEYARATKVELTDAGGTLAGRYAPVVRNPVGRLPGGGLVLGVADVVVANDPITGQGSNSAAKCAASYLSSILMHGDRPFDEAWMKATFDKYWFTTGMPVTEWTNAMLGAPPEHVLELIGAAGRLQPVADRFANGFDNPADFDSYFYEPEDTADYLAEVSSSLSPVPAE

Crispr_ID: NZ_CP024985_13

• CRISPR_ID: NZ_CP024985_13
• CRISPR_location: 3258515-3258629
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_13

Consensus_repeat	Method
AAGCGCACCCGGACCCGCAAGGTCGCCGAGGCCGCGCCGG	CRISPRCasFinder

spacers of NZ_CP024985_13

>13.1|3258555|35|NZ_CP024985|CRISPRCasFinder
TCACCGAGGCCGCCGCCGAGGCTCCCGCGAAGCCC

CRISPR arrays and Neighbor proteins around NZ_CP024985_13

CRISPR arrays

The CRISPR arrays of NZ_CP024985_13

>merge|NZ_CP024985|13|3258515-3258629|CRISPRCasFinder
AAGCGCACCCGGACCCGCAAGGTCGCCGAGGCCGCGCCGGTCACCGAGGCCGCCGCCGAGGCTCCCGCGAAGCCCAAGCGCACCCGGACCCGCAAGGTCGCCGAGGCCGCGCCGG

>NZ_CP024985|13|14|3258515-3258629|CRISPRCasFinder
AAGCGCACCCGGACCCGCAAGGTCGCCGAGGCCGCGCCGG	TCACCGAGGCCGCCGCCGAGGCTCCCGCGAAGCCC
AAGCGCACCCGGACCCGCAAGGTCGCCGAGGCCGCGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030226002.1|3264762_3265275_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030226000.1|3263605_3264730_+|magnesium-and-cobalt-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
NZ_CP024985.1|WP_030225994.1|3260556_3261426_-|PHP-domain-containing-protein	unknown	unknown	gnl|CDD|223686
NZ_CP024985.1|WP_030225998.1|3262643_3263228_-|suppressor-of-fused-domain-protein	unknown	unknown	gnl|CDD|377450
NZ_CP024985.1|WP_030225968.1|3246929_3247922_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NZ_CP024985.1|WP_030225987.1|3255469_3256228_-|hypothetical-protein	unknown	unknown	gnl|CDD|205967
NZ_CP024985.1|WP_030225991.1|3258727_3259585_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP024985.1|WP_030225982.1|3254718_3254946_+|DUF3107-domain-containing-protein	unknown	unknown	gnl|CDD|378634
NZ_CP024985.1|WP_030225977.1|3253544_3253760_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030226006.1|3266346_3267618_+|magnesium-transporter	unknown	unknown	gnl|CDD|225148
NZ_CP024985.1|WP_078950124.1|3265299_3266124_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037686363.1|3255066_3255366_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_167456791.1|3259680_3259833_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030225979.1|3253907_3254546_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP024985.1|WP_030225996.1|3261915_3262560_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030225993.1|3259888_3260494_-|MarC-family-protein	unknown	unknown	gnl|CDD|225006
NZ_CP024985.1|WP_030225972.1|3248898_3250635_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173871
NZ_CP024985.1|WP_030225970.1|3247918_3248902_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_CP024985.1|WP_030225976.1|3252429_3253410_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP024985.1|WP_030225974.1|3251007_3252426_-|DUF3152-domain-containing-protein	unknown	unknown	gnl|CDD|371483

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030226000.1|3263605_3264730_+|magnesium-and-cobalt-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.55889e-167
NZ_CP024985.1|WP_030225994.1|3260556_3261426_-|PHP-domain-containing-protein	gnl|CDD|223686	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only].	6.95242e-43
NZ_CP024985.1|WP_030225998.1|3262643_3263228_-|suppressor-of-fused-domain-protein	gnl|CDD|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	2.39373e-28
NZ_CP024985.1|WP_030225968.1|3246929_3247922_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.84923e-95
NZ_CP024985.1|WP_030225987.1|3255469_3256228_-|hypothetical-protein	gnl|CDD|205967	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like.	9.11493e-90
NZ_CP024985.1|WP_030225991.1|3258727_3259585_+|alpha/beta-fold-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	7.49953e-20
NZ_CP024985.1|WP_030225982.1|3254718_3254946_+|DUF3107-domain-containing-protein	gnl|CDD|378634	pfam11305, DUF3107, Protein of unknown function (DUF3107). Some members in this family of proteins are annotated as ATP-binding proteins however this cannot be confirmed. Currently no function is known.	6.59545e-34
NZ_CP024985.1|WP_030226006.1|3266346_3267618_+|magnesium-transporter	gnl|CDD|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	1.95095e-48
NZ_CP024985.1|WP_030225979.1|3253907_3254546_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.71569e-15
NZ_CP024985.1|WP_030225993.1|3259888_3260494_-|MarC-family-protein	gnl|CDD|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	2.53574e-44
NZ_CP024985.1|WP_030225972.1|3248898_3250635_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.12423e-171
NZ_CP024985.1|WP_030225974.1|3251007_3252426_-|DUF3152-domain-containing-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	5.24722e-59
NZ_CP024985.1|WP_030225976.1|3252429_3253410_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.68661e-28
NZ_CP024985.1|WP_030225970.1|3247918_3248902_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.64512e-72

Protein sequences

>NZ_CP024985.1|WP_030225987.1|3255469_3256228_-|hypothetical-protein
MSTVENASPADDGAPDGAQGIAAQDWATASASPQYRAAVVDLLGALAYGELAAFERLAEDAKLAPTLGDKAELAKMASAEFHHFERLRDRLAAIDAEPTEAMEPFAKGVDDFHRQTAPSDWLEGLVKAYVGDSIASDFYREVATHLDTDTRALVVGVLDDTGHGGFAVEKVRAAIEADPRCGGRLALWARRLMGEALSQAQRVVAERDALSTMLVGGVDGMAAGFDLAAVGEMFTRITKAHTKRMAALGLAA
>NZ_CP024985.1|WP_037686363.1|3255066_3255366_+|hypothetical-protein
MLLEAIGSGLLGLALAGAAVRVLAKRLPSTRTVLVSGVAGALFGAYLTHTALGPWHNTVAATCLGGLGVSAVVLSLLLRPAAGSGRRSRRPPFSLPSRG
>NZ_CP024985.1|WP_030225982.1|3254718_3254946_+|DUF3107-domain-containing-protein
MEVKIGVQHAPREIVLESDLSAEELESAVVAALSGTAPLLSLTDVKGRKVLVPSDRLSYVDLGEPSVRKVGFGAL
>NZ_CP024985.1|WP_030225979.1|3253907_3254546_+|TetR/AcrR-family-transcriptional-regulator
MTAIEQTEAARPRGTRLPRRARRNQLLGAAQEVFVAQGYHAAAMDDIAERAGVSKPVLYQHFPGKLDLYLALLDQHCEALLVAVRTALESTSDNKLRVAATMDAYFAYVEDEGGAFRLVFESDLTNEPAVRERVDRVSLQCAEAISDVIAEDTGLSKDESMLLAVGLGGVSQVVARYWLSSESPVARDTAVGLLTSLAWRGIAGFPLHGTEG
>NZ_CP024985.1|WP_030225977.1|3253544_3253760_+|hypothetical-protein
MTVDPAEPETFRKELRETLNTEAPEADAAEQDIEIQPQEDDSLTDLEPLEAPEADAAEQARVVPLDEDDYR
>NZ_CP024985.1|WP_030225976.1|3252429_3253410_-|alpha/beta-hydrolase
MSSTELPGVRSTVEPTPQVGAARVAEGEQLRTVALPGLEMNVRFRPPTREGLPPALFVHGLGGSSQNWSELMERLADSVDGEAVDLPGFGWSPPPADRDYSVTGLARAVIRHLDAAGRGPVHLFGNSLGGAVSTRVAAVRPDLVRTLTLVSPALPELRVQWSAVPTALLAVPGAAPLLVRLTRGLSAEQRTLGVTGLCYGDPSRVTEEGFRAAVEEMRRRMELPYFWEAMTRSSRGIVDAYTLGGQHGLWRQAGRVLAPTLLVYGGRDQLVSYRMARRAAAAFRGSRLLSLPEAGHVAMMEYPEVVAAAFRELLHDTDRNTEDSKG
>NZ_CP024985.1|WP_030225974.1|3251007_3252426_-|DUF3152-domain-containing-protein
MGRHSRKDSAPARPRPEAAPPEPEPEPFTPGPVFDGAPGARRSAEATVSHRGYAPPARPAPPGARPGGHPEQREPGGAWGAEPAPASAAVHGDWRGAPRAAAPTPPVHTPPARGADTPVRGARIPVRDAGMPARDTDTPAFGTPAVGFPRVTVAPPPPAPDPLTSTGSHRRVPGPRRPQAPETPAGSGAAEPSAPVRGGRIRTYTGMAAAAVTTVLAVVVAGQVVADSDSAPGNAHAAGDDAPERSLSGQSAASRSDGRATPANPPAAAAQPQTYEQQMARQLPIDAKLAGPGTFDTVPGFAKAPGKGKVVRYRVDVEQGLGLDPQLFAEAVQRTLNDPRSWGHGGAMTFERVPAGEADFVITLASPGTTGTWCAKSGLDTTVDNVSCDSAATERVMINAFRWAQGSPTYGPDQMLAYRQMLINHEVGHRLGHGHVSCQTPGSLAPIMQQQTKSLDIDNIHCLPNPWVFPGS
>NZ_CP024985.1|WP_030225972.1|3248898_3250635_-|ABC-transporter-substrate-binding-protein
MRQSQISRRVAAVAVSLVLAGGAAACGPEDAADKASAGGGPGASGSAPQKGGTLTVLNNEPQSDFDPARLYTSGGGNVPSLVFRTLTTRNREDGPAGAKVVPDLATDLGRPNADATEWTYTLKDGLKYEDGSPITTADIKYGIERSFAAELSGGAPYLRDWLVGGETYEGPYKDGGKGLDSIVVPDAKTIVFKLRKPEGEFPFLATQTQFAPVPKAKDTGVKYEEHPVSSGPYKVAKNTGDGETLLLERNENWDPKTDEERKAYPDRIDVRSGLDAAVINQRLSTSSGPDAAAVTTDTNLGPAELAQIGDNKELASRVGTGHFGYVNYLAFNPKVAPFDNPKVRQAIAYAVNRTSVVNAAGGSALAEPATTFLPEREAFGYTPYDPFPAGKTGNPAKAKELLKEAGFADGLTITLTHSNAQNRQTSPEIATAVQQALAAAGITVKLEGLETNAFNERRWDAKNTPGFFLSRWGADWPSGGPFLAPIFDGRQIVTNGSNYNHAQLNDPAVNAEIDEIAKLTDLAAAGKRWGALDKKIGEQALDVPLFHPVYKRLVGKGVKNVVISDWTGVLDISQVAVK
>NZ_CP024985.1|WP_030225970.1|3247918_3248902_-|ABC-transporter-permease
MSVLTTGPVPAAGVTTPAAGTGRQVWRRLRRRPSAVAAAAVLALLVLLALAAPLFAQLTGQDPNAYHDDLVDSARGGVPLGSFGGISADHWLGVEPGSGRDLFVRLLYGARISLLVALGATALQVLLGVAAGLTAALGHRILGRFIGGVTDVMIALPMLVLAIALTAVVPPDFPRPLLLVLVIGVLDWGGTARLVRAQTLSLRGLDFVEAARLSGNGTLRIARRELLPSLAAPVITLAAIKVPTNMVIEASLSFLGVGVKPPTPSWGQMLSSAQTWFRADPAYVLLPAGLLFVTVLAFTVLGDGVRTALDPREGSRLRVGTGKERTT
>NZ_CP024985.1|WP_030225968.1|3246929_3247922_-|ABC-transporter-permease
MTGFVLRRLGAALLVLLALSAVVYALFYLAPGDPARLACGERCNPQQIAQVREQLGLNDSVPTQYLRFLQGVLAGRDYSGGAGLVLHCDAPCLGFSYQNDRQVTELLLERLPATFSLALGALVIWLVIGVGTGLLSAVRRGGLTERLLTVVTLAATGTPVFILGLLLLMAVCAYLRWLPFPTYVPFGDDPEQWAWNLLLPWVTLGFFESAKYARLTRSSTLETLAEDHIRTFRAYGVGERALVTRHAVRGAVAPVIALSAVDFGTMIGGAVLTESLFGIPGLGKTLIDGVRVVDLPVVVGVVLTIGTAVVIAGAVADLLYAVADRRVALA
>NZ_CP024985.1|WP_030225991.1|3258727_3259585_+|alpha/beta-fold-hydrolase
MSKPPRLTLPPAARAYRLTTDRGAFAVHEAGEPVLGTALLLPGFTGSKEDFIALLEPLAAAGFRVLAVDGRGQYQTPGPREESAYGLQELGRDVLAQAAAAGGGPLHLVGHSLGGLVARAAVLRDASPFASLTLMSSGPGAIAEEQRARTKLLVAALEAMREDMPGVWEAMRAHDPEDAVPDAPELARFLRERWLGTVPEQLIATGRVLISEPDRVAELAEVPLPKLVLSGTVDYAWPVPLMDEMAVRLGASRVLVEAAEHSPNAENPQVTADSLVRFWRSLSAR
>NZ_CP024985.1|WP_167456791.1|3259680_3259833_+|hypothetical-protein
MRFEILRLNDVDGSAVDSTVVDAASVNRIVQQAAAVGQRILIRPAETASS
>NZ_CP024985.1|WP_030225993.1|3259888_3260494_-|MarC-family-protein
MFDFAVFGSLFLTLFVIMDPPGITPIFLALTSGRPAKVQRRMAWQAVCVAFGVIAVFGICGQQILDYLHVSVPALMIAGGLLLLLIALDLLTGKTDEPKQTKDVNVALVPLGMPLLAGPGAIVSVILAVQKADGFTGQVSVWCAIIAMHVVLWLTMRYSLVIIRIIKDGGVVLVTRLAGMMLSAIAVQQIINGVLQVVHGA
>NZ_CP024985.1|WP_030225994.1|3260556_3261426_-|PHP-domain-containing-protein
MRIDLHTHSTASDGTDTPAELVANAAAAGLDVVALTDHDTVGGYAEAIAALPPGLTLVTGAELSCRLDGVGMHMLAYLFDPQEPELSRERELVRDDRTPRAQAMVGKLRALGVDVTWEQVARIAGAGSVGRPHIATAMVELGVVPTVSDAFTADWLADGGRAYAEKHELDPFDAIRLVKAAGGVTVFAHPAAVKRGECVPESAIAALAAAGLDGIEVDHMDHDAATRDRLRGLAADLGLLATGSSDYHGSRKTCRLGEYTTDPEIYGEITRRATGAFPVPGAGGSAARA
>NZ_CP024985.1|WP_030225996.1|3261915_3262560_-|hypothetical-protein
MRGEPSCPKCGGRVRAPGLFADSWQCAVHGAVHPLQPVIPPSVEGLGVVVNRAQVPVWMPWPLPVGWLFTGVATAGDDRSGGRATAVACSGPGPLGGIGELLLIAEELGVGLGSRFAGIDGPDPGPYMKVSAPPHAKVVAAGRPTPLWHVAGAPDDRAVFAGEARGLWLWAIVWPEQSGLLMYDELVLTDLRDAGSEVELLPCGALTPRILSPS
>NZ_CP024985.1|WP_030225998.1|3262643_3263228_-|suppressor-of-fused-domain-protein
MAEILALVEARLRNAFGEPDARAAVTFLGTDRIEVLRFAEGDLVRYATLGMSAHPMTDPTAVVADPVRGPRAELVLTVRAGLAPTDKLLRPLAVLAASPMVEGLIVAPGASLDVGEPLWEGAAFSSVLVAEPGGLVEDLALDEPMDPVRFLPLLPMTANEAAWKRVHGAAALQERWLARGTDLRDPLRTAVALD
>NZ_CP024985.1|WP_030226000.1|3263605_3264730_+|magnesium-and-cobalt-transport-protein-CorA
MSMLPYLRAAVRPSLRRATPVQPGYDATRDPSASSAVVDCAVYRDGRRDPLEPGRGCLTPREALRRVREGGGFAWIGLHEPTEAEFAGIAATFGLHPLAVEDAVHAHQRPKLERYDDTLFTVFKTIHYVEHAELTATSEVVETGEVMCFTGPDFVITVRHGGQGSLRSLRHRLQDDPELLSRGPSAVLHSIADHVVDGYIAVAAAVQDDIDEVESAVFAAPAKGVSRGGDAGRIYQLKREVLEFKRAVSPLLRPMELLSERPMRLVDPDIQKYFRDVADHLARVHEQVIGFDELLNSILQANLAQASVAQNEDMRKITSWAAIIAVPTMICGVYGMNFEHMPELHWRYGYPMVMVAIVGSCFAIHRTLRRNGWL
>NZ_CP024985.1|WP_030226002.1|3264762_3265275_+|hypothetical-protein
MTLSALDLALVEEASKKSGLIWVRGAGADRALWHAWVDGAAHVLGDGPGEQPFPGLTDGAAAEVTVRSKDKGGRLVAWTAAVRELVPGSESWEAAVAELKGKRLNAPDSERMTERWARECRLLRLEPVAVADGLPDGSLAAAPLPSPAVTRRPVPAGLPKLLLKRKKAKR
>NZ_CP024985.1|WP_078950124.1|3265299_3266124_-|hypothetical-protein
MCAGLAVTATGCGGKAEDPDKGTNGIGKLGADKIEGQSKAAATAASSVHLSGSLVTGGKTFTLDMRLKADGGSGEVKSQNDTFQLLRVGEQLYLKAGAAFWGKSDSAGKLGDKYVKVPENDPSYKQFRGFTDMHVLLDGLLGLQGKLTKGAYTTVGHTRAVPISADAGKSGKLTVSLEGTPYPLLMERAGGAGRVELSEWGKPFPLEAPAQDQTVDYGSQLPTTKDGKDTGTGTGTGTGKGTGSGSGSGTGSGTGGPSPSKSQGSGQGSDPGSG
>NZ_CP024985.1|WP_030226006.1|3266346_3267618_+|magnesium-transporter
MAAGAPRIFVSHLSGVPVFDPNGDQVGRVRDLVAMLRVGGRPPRLLGLVVEVVSRRRIFLPMTRVTGVESGQVITTGVINMRRFEQRPTERLVLGELLDRRVTLVATGEEATVLDVAIQQLPARRDWEIDRIFVRKGKGGALRRRGEALTVEWSAVTGFSLEEHGQGAESLVATFEQMRPADLANVLHHLTPKRRAEVANALDDDRLADVLEELPEDDQVEILGKLKEERAADVLEAMDPDDAADLLSELPEEEKERLLTLMQPDDAADVRRLLSYEENTAGGLMTTEPIVLRPDATVADALARVRKSDLSPALAAQVYVCRPPDETPTGKYLGTVHFQRLLRDPPFTLVSSIVDTDLPPLRPDASLPAVTSYLAAYNMVAAPVVDESGSLLGAVTVDDVLDHLLPDDWRETDFHSEEAVRGH

Crispr_ID: NZ_CP024985_14

• CRISPR_ID: NZ_CP024985_14
• CRISPR_location: 3493191-3493279
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_14

Consensus_repeat	Method
CCGACGGCGAAGCCGAAGGACGTACCAGT	CRISPRCasFinder

spacers of NZ_CP024985_14

>14.1|3493220|31|NZ_CP024985|CRISPRCasFinder
CGAGCCCCGCTCCCCTCAGCCCCTCAGCCCC

CRISPR arrays and Neighbor proteins around NZ_CP024985_14

CRISPR arrays

The CRISPR arrays of NZ_CP024985_14

>merge|NZ_CP024985|14|3493191-3493279|CRISPRCasFinder
CCGACGGCGAAGCCGAAGGACGTACCAGTCGAGCCCCGCTCCCCTCAGCCCCTCAGCCCCCCGACGGCGAAGCCGAAGGCCGTACCAGT

>NZ_CP024985|14|15|3493191-3493279|CRISPRCasFinder
CCGACGGCGAAGCCGAAGGACGTACCAGT	CGAGCCCCGCTCCCCTCAGCCCCTCAGCCCC
CCGACGGCGAAGCCGAAGGCCGTACCAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030231143.1|3490090_3490897_+|purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|236183
NZ_CP024985.1|WP_030231110.1|3502442_3503018_+|VanZ-family-protein	unknown	unknown	gnl|CDD|377417
NZ_CP024985.1|WP_030231151.1|3484768_3486532_+|ATP-grasp-domain-containing-protein	unknown	unknown	gnl|CDD|227111
NZ_CP024985.1|WP_030231147.1|3487877_3489317_-|NAD(P)H-quinone-dehydrogenase	unknown	unknown	gnl|CDD|236112
NZ_CP024985.1|WP_030231141.1|3490925_3492572_+|phospho-sugar-mutase	unknown	unknown	gnl|CDD|100092
NZ_CP024985.1|WP_030231158.1|3481247_3482840_+|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|227136
NZ_CP024985.1|WP_030231137.1|3493861_3495349_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP024985.1|WP_037687472.1|3482858_3483074_+|acyl-CoA-carboxylase-subunit-epsilon	unknown	unknown	gnl|CDD|379386
NZ_CP024985.1|WP_030154970.1|3495345_3496041_-|two-component-system-response-regulator-AfsQ1	unknown	unknown	gnl|CDD|223816
NZ_CP024985.1|WP_030231127.1|3499186_3500623_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143429
NZ_CP024985.1|WP_030231132.1|3497801_3498152_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030231134.1|3497018_3497654_-|hypothetical-protein	unknown	unknown	gnl|CDD|223645
NZ_CP024985.1|WP_030231129.1|3498300_3499194_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|365919
NZ_CP024985.1|WP_030231145.1|3489501_3489939_+|gamma-glutamylcyclotransferase	unknown	unknown	gnl|CDD|372719
NZ_CP024985.1|WP_037687467.1|3483953_3484391_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_078950371.1|3486715_3487690_-|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl|CDD|224268
NZ_CP024985.1|WP_030231114.1|3500628_3501591_-|deoxyribose-phosphate-aldolase	unknown	unknown	gnl|CDD|235387
NZ_CP024985.1|WP_030231135.1|3496196_3496892_+|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NZ_CP024985.1|WP_030231112.1|3501705_3502341_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|371225
NZ_CP024985.1|WP_037687470.1|3483364_3483973_+|septum-formation-inhibitor-Maf	unknown	unknown	gnl|CDD|178901

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030231143.1|3490090_3490897_+|purine-nucleoside-phosphorylase	gnl|CDD|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	2.91089e-132
NZ_CP024985.1|WP_030231110.1|3502442_3503018_+|VanZ-family-protein	gnl|CDD|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	2.688e-18
NZ_CP024985.1|WP_030231151.1|3484768_3486532_+|ATP-grasp-domain-containing-protein	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NZ_CP024985.1|WP_030231147.1|3487877_3489317_-|NAD(P)H-quinone-dehydrogenase	gnl|CDD|236112	PRK07845, PRK07845, flavoprotein disulfide reductase; Reviewed.	0
NZ_CP024985.1|WP_030231141.1|3490925_3492572_+|phospho-sugar-mutase	gnl|CDD|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_CP024985.1|WP_030231158.1|3481247_3482840_+|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP024985.1|WP_030154970.1|3495345_3496041_-|two-component-system-response-regulator-AfsQ1	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.3651e-81
NZ_CP024985.1|WP_037687472.1|3482858_3483074_+|acyl-CoA-carboxylase-subunit-epsilon	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	3.05521e-08
NZ_CP024985.1|WP_030231137.1|3493861_3495349_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.52848e-54
NZ_CP024985.1|WP_030231127.1|3499186_3500623_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143429	cd07111, ALDH_F16, Aldehyde dehydrogenase family 16A1-like. Uncharacterized aldehyde dehydrogenase family 16 member A1 (ALDH16A1) and other related sequences are present in this CD. The active site cysteine and glutamate residues are not conserved in the human ALDH16A1 protein sequence.	0
NZ_CP024985.1|WP_030231134.1|3497018_3497654_-|hypothetical-protein	gnl|CDD|223645	COG0572, Udk, Uridine kinase [Nucleotide transport and metabolism].	1.34674e-14
NZ_CP024985.1|WP_030231129.1|3498300_3499194_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|365919	pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3. Succinate-semialdehyde dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2.1.28. Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27. Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9. Delta-1-pyrroline-5-carboxylate dehydrogenase EC: 1.5.1.12. Acetaldehyde dehydrogenase EC:1.2.1.10. Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This family also includes omega crystallin, an eye lens protein from squid and octopus that has little aldehyde dehydrogenase activity.	1.28291e-39
NZ_CP024985.1|WP_030231145.1|3489501_3489939_+|gamma-glutamylcyclotransferase	gnl|CDD|372719	pfam13772, AIG2_2, AIG2-like family. This family is found in bacteria and metazoa.	2.33773e-23
NZ_CP024985.1|WP_078950371.1|3486715_3487690_-|DeoR/GlpR-transcriptional-regulator	gnl|CDD|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.11048e-81
NZ_CP024985.1|WP_030231114.1|3500628_3501591_-|deoxyribose-phosphate-aldolase	gnl|CDD|235387	PRK05283, PRK05283, deoxyribose-phosphate aldolase; Provisional.	4.24136e-74
NZ_CP024985.1|WP_030231135.1|3496196_3496892_+|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.56598e-60
NZ_CP024985.1|WP_030231112.1|3501705_3502341_+|PH-domain-containing-protein	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	0.000841509
NZ_CP024985.1|WP_037687470.1|3483364_3483973_+|septum-formation-inhibitor-Maf	gnl|CDD|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	1.49159e-93

Protein sequences

>NZ_CP024985.1|WP_030231141.1|3490925_3492572_+|phospho-sugar-mutase
MQEQDDLITRAQAWLAEDPDRETADELAALIASGDTAELADRFSGTLQFGTAGLRGELGAGPMRMNRAVVIRAAAGLAAYLKAQGHAGGLVVVGYDARYKSADFARDTAAVMTGAGLRAAVLPRPLPTPVLAYAIRHLGAVAGVEVTASHNPPRDNGYKVYLGDGSQIVSPADTEIAAEIAKVTTLDSVPRPGSGWQDLGDEVLEAYLARTDAVLTPGSPRGVRTVYTAMHGVGKDVVLAAFARHGFPTPVLVAEQAEPDPAFPTVAFPNPEEPGAMDLSFAKAAEVNPDIVIANDPDADRCAVAVPTADGWRMLRGDEVGALLAAHLVHKGARGVFAESIVSSSLLGRIAEAAGVGYEETLTGFKWIARVEGLRYGYEEALGYCVDPEGVRDKDGVTAALLVAELASVLKEQGRTLTDLLDDLAMAHGLHHTDQLSVRVSDLSVIADAMAALRAEPPTTLAGLRVVSAEDLNRGTDKLPPTDGLRYYLDGAYKARVICRPSGTEPKLKCYLEVVVPVAEASDLTTARATGQEILDAIKKDLSAAMGL
>NZ_CP024985.1|WP_030231143.1|3490090_3490897_+|purine-nucleoside-phosphorylase
MNASVIDPFAAADAAATRLRELTGVDSHDVALVMGSGWAPAAEALGAPEAEFPVTELPGFPPPAVEGHGGKIRSYKIGDKRALLFLGRTHYYEGRGVAAVAHGVRTAVAAGCKTVVLTNGCGGLREGMKPGQPVLISDHLNLTATSPIVGANFVDLTDLYSPRLRAMCKEIDASLEEGVYVQFPGPHYETPAEINMIRVMGADLVGMSTVLEAIAAREAGAEVLGISLVTNLAAGLSGEPLNHEEVLQAGRDSASRMGTLLTQVLARI
>NZ_CP024985.1|WP_030231145.1|3489501_3489939_+|gamma-glutamylcyclotransferase
MSLYAAYAGNLDPRLMTRRAPHSPLRGTGWINDWRLTFGGEQMGWEGALATIVEAPRHQVFVALYDIAPLDEDSMDRWEGVGLDIYRRMRIRVHTLDGEEAAWVYVLNGYEGGLPSARYLGEIADAAESAGAPHDYVMELRKRPC
>NZ_CP024985.1|WP_030231147.1|3487877_3489317_-|NAD(P)H-quinone-dehydrogenase
MTRIVIIGGGPGGYEAALVGAQLGAEVTVVDCDGLGGASVLTDCVPSKTLIATAEVMTTFDSSYEELGIVVADDTPPMEQAARVVGVDLGKVNRRVKRLALAQSHDITASVTRAGARVLRGRGKLGGPQGIDGTRDVIVTAADGTETILTADAVLIATGGTPREIPDAMPDGERILNWTQVYDLEELPEELIVVGSGVTGAEFAGAYQALGSRVTLVSSRDRVLPGEDPDAAAVLEDVFRRRGMNVVGRSRAESVKRVGDRVEVTLSDGRVIAGTHCLMAVGAIPNTQNMNLEESGVRLKDSGHIWTDKVSRTSSPGVYAAGDVTGVFALASVAAMQGRIAMYHFLGDAVTPLNLKTVSSNVFTDPEIATVGYTQADVDAGKIDARVVKLPLLRNPRAKMQGIRDGFVKMFCRPGTGIVVGGVVVSPRASELIHPISIAVDNNLTVEQIANAFTVYPSLSGSIAEVARQLHTRKTAGEA
>NZ_CP024985.1|WP_078950371.1|3486715_3487690_-|DeoR/GlpR-transcriptional-regulator
MFAAERRQLILEMVRANGAVSLRELARVVQTSEVTVRRDVRALEAEGLLDRRHGGAVLPGGFTRESGFPQKSHLATAEKTAIADIAAGLVEEGEAVVVGAGTTTQELARRLARVPGLTVVTNSLLVAQALAHANRVEVVMTGGTLRGSNYALVGSGAEQSLQGLRVSRAFLSGSGLTAERGLSTSNMLSASVDRALVQAAAEVVVLADHTKLGTDTMFQTVPTDIMTRLVTDEPPPHDDRAATELQALADQGVQITVAGSSAASGGGHGGAPGGDGMQGRRPRRESPLPVQRRGGPTAQLRSAPASMLEQQAGERARVADMRRR
>NZ_CP024985.1|WP_030231151.1|3484768_3486532_+|ATP-grasp-domain-containing-protein
MRKVLIANRGEIAVRVARACRDAGIASVAVYADPDRDALHVRAADEAFALGGDTPATSYLDIAKVLQAAADSGADAIHPGYGFLSENADFAQAVIDAGLTWIGPPPQAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGSDEVVAFAQEHGLPIAIKAAFGGGGRGLKVARTLEEVPELYDSAVREAVAAFGRGECFVERYLDKPRHVETQCLADSHGNVVVVSTRDCSLQRRHQKLVEEAPAPFLSEAQNAELYAASKAILKEAGYVGAGTVEFLVSADGLISFLEVNTRLQVEHPVTEEVSGIDLVREMFRIADGEELGYGDPVLRGHSFEFRINGEDPGRGFLPAPGTVTKFAPPTGPGVRLDTGVESGSVIGPAWDSLLAKLIVTGATREQALQRAARALAEFEVEGMATAIPFHRAVVTDPAFAPTDGSPFTVFTRWIETEFVNEIPAFVAPAAEDTEDEPGRETVVVEVGGKRLEVSLPSSLGMTLARTAAAGGAKPKRRAAKKSGPAASGDTLASPMQGTIVKVAVEEGQQVNEGDLVVVLEAMKMEQPLNAHRSGTIVGLSAEVGASLTSGATICEIKD
>NZ_CP024985.1|WP_037687467.1|3483953_3484391_-|hypothetical-protein
MLRRLVAGLGALALVAEAAVLVLVHLVLGRTTANQSMSIAGSDPQLMSRLTYGLGAAIGAFLLLGAVLLALTALRDRAPGRFARVVLVAVALTHVLLGAIAAGLVTWSAFAVTMVILCLLVLTLTLYAGGRDEPTGARGLRPTSP
>NZ_CP024985.1|WP_037687470.1|3483364_3483973_+|septum-formation-inhibitor-Maf
MTVEPQRTLVLASASPARLNLLRQAGLAPHVIVSGFDEDTLDHDEPAALALALAEAKAGVVAGLAEAAGALVIGCDSVLELDGEALGKPADAAEATARWKAMRGRAGVLRTGHCVIDTATGRQVSATASTTVRFGEPSDAEVAAYVASGEPLHVAGAFTLDGLSSPFIDGIDGDHGNVIGLSMPLLRSLLGELDVSITDLWA
>NZ_CP024985.1|WP_037687472.1|3482858_3483074_+|acyl-CoA-carboxylase-subunit-epsilon
MMIKVVKGNPTPEELAAALAVVRARAAALASAPSGAPRVPDEWAAPRRVARHRVPQPGPRAWGRTYWPGQR
>NZ_CP024985.1|WP_030231158.1|3481247_3482840_+|acyl-CoA-carboxylase-subunit-beta
MSQPSEPIDMHTTAGKLADLRRRVEEATHAGSARAVEKQHAKGKLTARERVALLLDEGSFVELDEFARHRSTNFGLEKTRPYGDGVVTGYGTVDGRPVAVFSQDFTVFGGALGEVYGQKIIKVMDFALKTGCPVIGINDSGGARIQEGVSALGMYGEIFRRNVHASGVIPQISLVVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNSTSGVAHHMAGDEKDAIEYVKSLLAYLPSNNLSEPPSFPEEADTEVSDSDLELDTLIPDSANQPYDMHTVIEHVLDDGEFLETQSLFAPNILTGFGRVEGHPVGIVANQPMQFAGCLDINASEKAARFVRTCDAFNVPVLTFVDVPGFLPGTDQEYNGIIRRGAKLIYAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRAIAEAGENEVEEVRARLIGEYEDALLNPYTAAERGYIDAVTMPSETRAHVVKGLRQLRTKRESLPPKKHGNIPL
>NZ_CP024985.1|WP_030231137.1|3493861_3495349_-|HAMP-domain-containing-histidine-kinase
MIRALFAGRRWTSLRLRLLVVFALVALTAAVSASGIAYWLNREAVLTRTQDAALGDFRQEMQNRAAALPADPTSEEMQRTAELMAGSSPGYSVLLVHERKDGRKVFGAAGADSFGLDDVPKSLQHAVNDRQKTTAANDAEYHMYWQRTKPNGNPYLVGGTRIVGGGPTGYMYKSLATERADLNALGWSLTIATGLALLGSALLAQAAARTVLKPVQRLGDAARRLGEGELDHRLEVSGTDELADLAHTFNKTAEALEKKVADMSAREEASRRFVADMSHEMRTPLTALTAVAEVLEEEVEDLDPMIAPAVGLVVSETRRLNDLVENLMEVTRFDAGTARLVLDDVNVADQVTACIDARAWLDAVELDAGRGIVARLDPRRLDVILANLIGNALKHGGSPVRVSVAVEGEQLVIAVRDNGPGIPEEVLPHVFDRFYKASASRPKSDGSGLGLSIAMENAHIHGGDITAENGADGGAVFTLRLPMDVGKVIPDDVDA
>NZ_CP024985.1|WP_030154970.1|3495345_3496041_-|two-component-system-response-regulator-AfsQ1
MGQNEPVPFLLLIEDDDAIRTALELSLSRQGHRVATAATGEDGLKLLREQRPDLIVLDVMLPGIDGFEVCRRIRRTDQLPIILLTARSDDIDVVVGLESGADDYVVKPVQGRVLDARIRAVLRRGEREASDSAVFGSLVIDRAAMTVTKNGEDLQLTPTELRLLLELSRRPGQALSRQQLLRLVWEHDYLGDSRLVDACVQRLRAKVEEVPSSPTLIRTVRGVGYRLDSPQ
>NZ_CP024985.1|WP_030231135.1|3496196_3496892_+|SigE-family-RNA-polymerase-sigma-factor
MNTLHSTTTSAVVTRLHDVNRRAGVRNVTVARPRPAHVTAIDANQYQAVPAPRTPCSTSEAEFTAYVQERRAALYATAFHLTGDRHEAEDLLQSALFSTYRAWDRISDKAAVGGYLRRTMTNLHISAWRRRKLNEYPTEELPETASDTDAMRGTELRAVLWQALARIPEPQRTMLVLRYYEGRTDPEIAEILGISVGTVKSSIWRSLRRLRDDEALSFGRDEAESFGELVA
>NZ_CP024985.1|WP_030231134.1|3497018_3497654_-|hypothetical-protein
MSCSSPLPTRVVLLTGPSGSGKSSLAARSGLPVLRLDDFYKEGTDPTLPLVEGSSDIDWDSPLSWDADAAVAAIGELCATGRTEVPEYSIATSSRTGTERLDIDRTPLFIAEGIFAADIVARCQELGLLADAICLRGRPSTTFRRRLARDLREGRKSVPFLLRRGWRLMRAERGIVARHVALGAYACAGDEALGRLAAAAAGRHRTANTPA
>NZ_CP024985.1|WP_030231132.1|3497801_3498152_+|hypothetical-protein
MGRHAASDPSPKRLRSAGLTLSMAGAALAMAAGAAQAGELDVPAAVAGVANPIGDLKVNPLAHTGVDPLDNGVATKVADFPSVGTGMVTGILTQGPSVKEIPTAAVSNLLSPVLPK
>NZ_CP024985.1|WP_030231129.1|3498300_3499194_-|aldehyde-dehydrogenase-family-protein
MSESTRLNVFKTYKLYVGGKFPRSESGRVYEVTDSKGNWLANAPLSSRKDARDAVVAARKAFGGWSGATAYNRGQILYRIAEMLEGRRDQFVREVGEAEGLSKSKAGAVVDAAIDRWVWYAGWTDKIGQIVGGANPVAGPFFNLSTPEPTGVVTVVAPQDSSFLGLISVIAPVIATGNTAVVITSEKSPLPALSLGEVLATSDLPGGVVNILSGKAGEMGPHLASHQDVNAIDLAGADAALAKELEIAAADNLKRVLRPQPVDDWTADPGTTRLTAFLETKTVWHPTGSLGAGGSSY
>NZ_CP024985.1|WP_030231127.1|3499186_3500623_-|aldehyde-dehydrogenase-family-protein
MASLFEYAPAPESRSVVDIAPSYGLFIDGEFTDAADGKVFKTVSPSSEEVLSEVAQAGAADVDRAVKAARKAFEKWSALPGSERAKYLFRIARIIQERSRELAVLETLDNGKPIKETRDADLPLVAAHFFYYAGWADKLDHAGYGANPRPLGVAGQVIPWNFPLLMLAWKIAPALATGNTVVLKPAETTPLSALFFADICRQAGLPKGVVNILTGYGDAGAALVEHPDVNKVAFTGSTAVGKAIARQIAGTDKKVTLELGGKGANIVFDDAPIDQAVEGIVNGIFFNQGQVCCAGSRLLVQESIHDELLDSLKRRLSTLRLGDPLDKNTDIGAINSAEQLARITALAETGEAEGAERWSPACELPSAGYWFAPTLFTNVTQAHTVARDEIFGPVLSVLTFRTPDEAVAKANNSQYGLSAGIWTEKGSRILAVANKLRAGVVWANTFNKFDPTSPFGGYKESGFGREGGRHGLEGYLDV
>NZ_CP024985.1|WP_030231114.1|3500628_3501591_-|deoxyribose-phosphate-aldolase
MPTTLTAFADVTTSDSALRRFLHGLPGVDAVGLEARAASLGTRSIKTTAKAYAIDLAISMIDLTTLEGADTPGKVRALAAKAVNPDPTDRSTPMTAAVCVYPDMVATAKAGLNGADVKVASVATAFPAGRAALPVKLADTRDAVAAGADEIDMVIDRGAFLAGRYLETYELIKAVKEACVREDGTAARLKVIFETGELSTYDNIRRASWIGMIAGADFIKTSTGKVGVNATPANTLLMLEAVRDFKAQTGIQIGVKPAGGIRTTKDALKFLVLVNETAGADWLTNEWFRFGASSLLNDLLMQRQKLSTGRYSGPDYVTVD
>NZ_CP024985.1|WP_030231112.1|3501705_3502341_+|PH-domain-containing-protein
MTTPSPHEPVYADRVYRSPMAVVTGVLLLALIAWLCGDAVVRGEGSARWVGLAIALFAVPLTVAFTLRPAVFANDDRMRVRNPFRVIVLPWAAVDAVRAGYSAEVLAEGSKYQLWSVPVSLRERKKASRKFSRRDALGGKGLGQDGDAAAAAAAGPERAAADQVVDELRELAERGAGRPGAQGSVSVKWAYEIIAPAVVGAVALIVLLATG
>NZ_CP024985.1|WP_030231110.1|3502442_3503018_+|VanZ-family-protein
MHRHEGSGSAATATQFPVRLRLLSGALLAAHLVLVGWLTLRPLDVPWAAAANLDFLEGIRADLAYGPLEAAQRIGEGVALLAPLGALLPLTGGRLTHSSLGAWSSLARTTAAAVLISLSIEMLQSAVPGRVVDVDSLLLNTLGVVLVHLAVLPALRARVRRSLRPQGSTPRITRVGLPPWAEVLSAVPREY

Crispr_ID: NZ_CP024985_15

• CRISPR_ID: NZ_CP024985_15
• CRISPR_location: 3840388-3840496
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_15

Consensus_repeat	Method
CCGCTCGACAACCACGCTTCGGGCG	CRISPRCasFinder

spacers of NZ_CP024985_15

>15.1|3840413|59|NZ_CP024985|CRISPRCasFinder
TCGAGATCAATCCGCTGGATCCGCTCGACCCTCCGGCCCCGAAGCAGCCGGGCGAGAAG

CRISPR arrays and Neighbor proteins around NZ_CP024985_15

CRISPR arrays

The CRISPR arrays of NZ_CP024985_15

>merge|NZ_CP024985|15|3840388-3840496|CRISPRCasFinder
CCGCTCGACAACCACGCTTCGGGCGTCGAGATCAATCCGCTGGATCCGCTCGACCCTCCGGCCCCGAAGCAGCCGGGCGAGAAGCCGCTCGACAACCACGCCTCGGGCG

>NZ_CP024985|15|16|3840388-3840496|CRISPRCasFinder
CCGCTCGACAACCACGCTTCGGGCG	TCGAGATCAATCCGCTGGATCCGCTCGACCCTCCGGCCCCGAAGCAGCCGGGCGAGAAG
CCGCTCGACAACCACGCCTCGGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_158740799.1|3829776_3830400_-|hypothetical-protein	unknown	unknown	gnl|CDD|235777
NZ_CP024985.1|WP_030236503.1|3848920_3849364_+|SRPBCC-domain-containing-protein	unknown	unknown	gnl|CDD|176864
NZ_CP024985.1|WP_030236495.1|3846797_3847250_+|hypothetical-protein	unknown	unknown	gnl|CDD|224462
NZ_CP024985.1|WP_030236507.1|3849375_3850191_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP024985.1|WP_051841267.1|3850277_3851048_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_030236479.1|3835692_3836913_-|amidohydrolase	unknown	unknown	gnl|CDD|368185
NZ_CP024985.1|WP_030236487.1|3840916_3841651_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP024985.1|WP_030236466.1|3831943_3833182_-|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340817
NZ_CP024985.1|WP_030236472.1|3834942_3835359_-|PIN-domain-nuclease	unknown	unknown	gnl|CDD|350322
NZ_CP024985.1|WP_030236475.1|3835355_3835586_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin	unknown	unknown	gnl|CDD|378324
NZ_CP024985.1|WP_030236493.1|3845635_3846787_+|lipid-transfer-protein	unknown	unknown	gnl|CDD|181147
NZ_CP024985.1|WP_030236469.1|3833843_3834926_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP024985.1|WP_078950534.1|3841651_3843598_-|hypothetical-protein	unknown	unknown	gnl|CDD|271234
NZ_CP024985.1|WP_030236481.1|3837068_3840146_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276938
NZ_CP024985.1|WP_078950537.1|3843705_3845439_-|fatty-acid--CoA-ligase-family-protein	unknown	unknown	gnl|CDD|236072
NZ_CP024985.1|WP_030236457.1|3828828_3829158_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030236498.1|3847246_3848023_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|119339
NZ_CP024985.1|WP_030236463.1|3830555_3831428_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|226119
NZ_CP024985.1|WP_030236459.1|3829284_3829725_+|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240041
NZ_CP024985.1|WP_051841266.1|3848023_3848650_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_158740799.1|3829776_3830400_-|hypothetical-protein	gnl|CDD|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	0.00900071
NZ_CP024985.1|WP_030236503.1|3848920_3849364_+|SRPBCC-domain-containing-protein	gnl|CDD|176864	cd07822, SRPBCC_4, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	6.80371e-35
NZ_CP024985.1|WP_030236495.1|3846797_3847250_+|hypothetical-protein	gnl|CDD|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	3.74685e-22
NZ_CP024985.1|WP_030236507.1|3849375_3850191_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.80032e-14
NZ_CP024985.1|WP_051841267.1|3850277_3851048_+|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	2.2142e-31
NZ_CP024985.1|WP_030236479.1|3835692_3836913_-|amidohydrolase	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	5.03622e-29
NZ_CP024985.1|WP_078950534.1|3841651_3843598_-|hypothetical-protein	gnl|CDD|271234	cd15482, Sialidase_non-viral, Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.	2.26415e-84
NZ_CP024985.1|WP_030236466.1|3831943_3833182_-|glycosyltransferase-family-1-protein	gnl|CDD|340817	cd03784, GT1_Gtf-like, UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.	1.02044e-61
NZ_CP024985.1|WP_030236472.1|3834942_3835359_-|PIN-domain-nuclease	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	3.37144e-61
NZ_CP024985.1|WP_030236481.1|3837068_3840146_+|tetratricopeptide-repeat-protein	gnl|CDD|276938	cd15831, BTAD, Bacterial Transcriptional Activation (BTA) domain. The Bacterial Transcriptional Activation (BTA) domain is present in the putative transcriptional regulator Mycobacterium EmbR and the related Streptomyces antibiotic regulatory protein (SARP) family of transcription factors, which includes DnrI and AfsR, among others. Members of this family contain an N-terminal DNA-binding domain, followed by the BTA domain, and many have diverse domains at the C-terminus. EmbR contains an C-terminal forkhead-associated (FHA) domain, which mediates binding to threonine-phosphorylated sites in a sequence-specific manner. The BTA domain of EmbR contains three Tetratricopeptide repeats (TPRs) and two C-terminal helices. The TPR motif typically contains 34 amino acids, and 5 or 6 tandem repeats of the motif generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein.	4.11688e-41
NZ_CP024985.1|WP_030236475.1|3835355_3835586_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin	gnl|CDD|378324	pfam09957, VapB_antitoxin, Bacterial antitoxin of type II TA system, VapB. VapB is the antitoxin of a bacterial toxin-antitoxin gene pair. The cognate toxin is VapC, pfam05016. The family contains several related antitoxins from Cyanobacteria and Actinobacterial families. Antitoxins of this class carry an N-terminal ribbon-helix-helix domain, RHH, that is highly conserved across all type II bacterial antitoxins, which dimerizes with the RHH domain of a second VapB molecule. A hinge section follows the RHH, with an additional pair of flexible alpha helices at the C-terminus. This C-terminus is the Toxin-binding region of the dimer, and so is specific to the cognate toxin, whereas the RHH domain has the specific function of lying across the RNA-binding groove of the toxin dimer and inactivating the active-site - a more general function of all antitoxins.	2.01469e-08
NZ_CP024985.1|WP_030236493.1|3845635_3846787_+|lipid-transfer-protein	gnl|CDD|181147	PRK07855, PRK07855, lipid-transfer protein; Provisional.	0
NZ_CP024985.1|WP_030236469.1|3833843_3834926_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.78248e-12
NZ_CP024985.1|WP_030236487.1|3840916_3841651_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.40832e-25
NZ_CP024985.1|WP_078950537.1|3843705_3845439_-|fatty-acid--CoA-ligase-family-protein	gnl|CDD|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP024985.1|WP_030236498.1|3847246_3848023_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|119339	cd06558, crotonase-like, Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.	8.81464e-40
NZ_CP024985.1|WP_030236463.1|3830555_3831428_-|trypsin-like-serine-protease	gnl|CDD|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	1.75053e-13
NZ_CP024985.1|WP_030236459.1|3829284_3829725_+|NUDIX-domain-containing-protein	gnl|CDD|240041	cd04685, Nudix_Hydrolase_26, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	3.47052e-29

Protein sequences

>NZ_CP024985.1|WP_030236481.1|3837068_3840146_+|tetratricopeptide-repeat-protein
MDGIPAIPHQRNHPEAARSRNSADAPAAPEPPAPPETPAQAPAAPAAAEPPHAPGAPEPSPADNRFAVLGPIRAWRGPEALPSGSPQQRALLAVLLLRDGRTATAPELIDAIWGEDPPPQALATIRTYASRLRKVLHPGLLVSDAGGYAIRLRHQEALDLGIARSLAADAEAARSAGDRALARTLLARALDLWDGEPLAGVPGPHADTERTRLAEWRLQLLETRLDLDLEVGHHAEAVSELTALTAAHPLRERLRELLMLALYRSGRQAEALAVYADTRRLLADELGVDPRPELSALQQRILNADAELARAEAPVTTAAPAPVRPAQLPATVPDFTGRAPFVSELGEILAGAEGQVMAVSALAGIGGVGKTTLAVHVAHAARPHFPDGQLYADLQGTDPRPAQPEAVLGSFLRALGIPDSSIPDSAADRAALYRTVLDGRRVLVLLDNARDAAQVRPLLPGTAGCAALVTSRVRMSGLAGAHLVDLDVMSPEEALQLFTRIVGAERVGAERQAALDVVGACGFLPLAIRIAASRLAARRTWTVSVLAAKLADERRRLDELQAGDLAVKATFELGYGQLEPAQQRAFRLLGLADGPDISLCAAAAVLDLPEHDTEDLLEALVDCSLLESAAPGRYRFHDLVRLYARACAERDEQPARGQDAALDRLLDFYLATASRVYAVERPGDRLPAHLSPTRHPGLVLTEPRAALDWLFAEADPLLACVRQAAGRPAALRRAVDLLWAAKDLAESGANSKQYESAALTLREAARSAKDPRAEGRARTALTMVHLVAGRFTEGDEEARQAMDLAREAGDPLPSCWAPNDRGIIALYQGRYRDGERYLLEAIENFRADANFIGEASALCNLSRIHVELGRLPSAIDLAQQGIAIYDRMGLTLRLANGRYALGIALTQAGRLREALIQLGEALSLFHDNRQPLWEGVTHFRLAEAHLAARRPTLAAKHAEQAIALRGIGGEWRRATVLTVLGKALRRLGQPDRAQACWRDAETVFTQLGSSELAEVQALLAAELAA
>NZ_CP024985.1|WP_030236479.1|3835692_3836913_-|amidohydrolase
METFPKIISVDDHTVEPPHVWRDRLPSKYRDTGPRIVRAPLKEMTFLGGKFAPVMGAKGDDGPIGDWWVYEDLHRPLTRLDTAVGYDRDEIKLEVITYEQMRPGSFSVPDRLADMDVNHVQSALCFPTFPRFCGQTFTEAKDRELGLLGVRAYNDWMVEEWCGPEARGRLIPLTLVPLWDARLAAAEVRRNAARGVRAVAFSEIPPHLGLPSIHTDDWDPFLQACDETGTVIAMHIGSSSRMPSTSADAPPAVGSTITFANCCFSMVDWLMSGKFERFPNLRIMYAEGQIGWIPYILERANVVWEENRGWGGVADKVHRPPSELFAEHVFGCFFDDAFGLRNLDAIGVANVLYETDYPHSDSTWPKSREVGESQMGHLAPDVVERIVRGNAIDLLGLTGEGLWAGA
>NZ_CP024985.1|WP_030236475.1|3835355_3835586_-|type-II-toxin-antitoxin-system-VapB-family-antitoxin
MARTVIDVDDALLAEAAELFGTKTKVATVNAALRDAVNRRKREEFLNWLAEGGLPDLTGPVELLAAEGGHVQDRAA
>NZ_CP024985.1|WP_030236472.1|3834942_3835359_-|PIN-domain-nuclease
MTRHFLIDKSALARYPKPAVRAVVNPLHTAGVLAVCGAVELEVLYSARSKSDADRVRAGLGAFAWLSTPDEAWDRALEVQEQLIVAGNWKAVSLPDLIIAATAERHEATVLHYDGDYDMIAKVTGQPTRWVVPPGTAD
>NZ_CP024985.1|WP_030236469.1|3833843_3834926_+|alpha/beta-hydrolase
MIGIIAAATAASFAAPVAGLFAHRAVRRAGHARLMRIGTPNGIDEQGLVRIGGIEQWISVRGEDRANPVLLEIHGGPGAANSPYGARTRSWEKHFTLVRWDMRGAGLTFAHGGPEGQGEITFERVYEDAVEVTRHVLARLGVERVVLMPNSFGTVFGLRLARNHPELYSAYVGTDQNIQEAGRDTSAYDATLERLRTAGKAKDVATVEAMGCDPRRWTPAQRSSYDKLCAGSDPLTLDTVKKVIVGSLWLSPLYSLGRVKAYFKGQGFSEPLTEGTGGFDDFADGTRFEVPFFVFQGERDVITPAARARLFFDAVEAPVKAFELIGDASHFAALRRPERFLELLLQHVRPVVTAGRNVTA
>NZ_CP024985.1|WP_030236466.1|3831943_3833182_-|glycosyltransferase-family-1-protein
MRVLLSAYDSRGGVEPLVGLAVRLLELGAEVRVCAPPDEEFAKRLATIGVEMTPTGQSVRDLVTGKTPPSPGGVPKRAAALVAAFYEQARAAAEGCDVLVATGLVPAVAGVKAVSEKLGIPYVYASYQPVSLPSPHHQPMARPGRPLAPDVTDNVALWEQDARDAQEVFGEAINTHRASIGLPVLDNVRDHVFTDRPWLATDPTLAPWVQPADLHVVQTGAWVLPDERPLPADLVEFLDAGAPPVYVGFGSIPMRDPQDVARVAIEAIRAQGRRAVLSRGWADLALIDDQDDCFVVGEANHQALFRRTAAVVHHGGAGTTATATWSGTPQVIVPQGADQPYFAARVADLGIGAAHEGPTPTVESLSAALKTALTPDTSARATAVAAAFQADGAAVAAQLLFDLVRQTPTTKN
>NZ_CP024985.1|WP_030236463.1|3830555_3831428_-|trypsin-like-serine-protease
MLREGEAGGIMAVDKRTVVTAVLCAVAALGASAAVAELVPPPDGADAPVRAKSATPSGSPTGQSRSKASKPQLASPPPAAVTPKPGGPAAFTGALFTGGLDGDHFCTATVVRSPGKNLLITAGHCLMEGEQTRDGGAVFAPAYANGVAPYGTWKIEQVYEDERWADGTDDDYDLAFARVAPDAKGRNIEDVIGGAPLDTSGRAGEEVTVTGYPADRKVPRTCTAVSVRLSPTEQRFDCSDFPGGTSGSAWIGRDGKIIGILTGGDTDDVSTSTVLGDYAAQLYAKATAKR
>NZ_CP024985.1|WP_158740799.1|3829776_3830400_-|hypothetical-protein
MIESTPRRTVPLVLALAVAAAAPTATAAAATTAAAAPAPAASATAFAGIRGWARMAYGDPRDDVRILVDAHGSFDGRDPAVAARSWGTFRIQHFMGGPSDGSDGPRPGFNWGDFRVDCVRVDGADVAVTGRLVDAGPDWEEFLHGTPPARMGVSFHVAAPGTGETRIGITAPPPAGAPELAPCAAGPADAGTTAGGYTLTDTRRRSG
>NZ_CP024985.1|WP_030236459.1|3829284_3829725_+|NUDIX-domain-containing-protein
MRTPRQAARIVVLSPSGSVFLFRENNSEVGIHWLPPGGGIDPGESPEECVRRELREETGWTDLEPQRLLCTWEHDFTHQGVPVRQHEHIYVTTGPRREPRLEAPDIHWQWLSQQRLATLGEPLWPPRLPQLLAGTPAEPVHLGLVT
>NZ_CP024985.1|WP_030236457.1|3828828_3829158_+|hypothetical-protein
MRKSATVLAALAFALAGASPANAAVDSQCGRYICVMTAHHNRFVQDITVQTRDGNPGVLRAYWGEFRSGRVTAASHRWNVGYEQAGAKLVCGGLERDGRTIEDGICVTI
>NZ_CP024985.1|WP_030236487.1|3840916_3841651_+|class-I-SAM-dependent-methyltransferase
MFTSQGPSLRELAVQALSSVEHGYDLLAPKFDRTPFRTPDRMLDAVEETLAQREGSFSDGLDLCCGTGAGLPMLRRLCRERVTGVDLSTGMLAEAARQHPEGVDLLRGDALALPEALTDSYDLAVSFGAFGHFLPAERPALFANVHRALRPGGVFAFPVGAPIPLSSPLGWAVAGFDAAMRVRNAVWRPPFVMYYRTFPLGPVRADLAAAGFGVETVPLEHFGYREDGSPRWRLLLARKSGPAG
>NZ_CP024985.1|WP_078950534.1|3841651_3843598_-|hypothetical-protein
MSSHQPVVRFPGGARARLWAVAGAAAALAVVLLLALLPDPPAAPDGPDGDGSGGGRRGLTAAVSAPFNAFTEGYDCYRIPTLTTTKDGTLLAIAEARTASCNDIGDIDLVMKRSTDEGRTWGPMEVIRGTGDPGAYGNPAPVVDSASGRISLLYAYSTWAPDAAGNRVRGPRELRLAHSTDDGVHWSTEPNPQPQLKGADWAWVSVGPGHGIQLTPTRPDRPGRLVVGADYRTESNESGAQLLYSDDGGLTWQAGARWGAPEGTPAPNEPALTQLPDGRIYVNARSTATCGTDDHRIAALVDDAAAPAFPAPGFQPVTGLIAPPASGSLLQLPGGPLLLSAPSRPGAEFSDRWTLAVRTSEDGGRTWSANGAVVLRERAGYSDMAVLPGGRIGMLYETANGTPHGYIKFTAFGPQELRAAAEDLTPRRTADTSAGHHDAIVHGAPRLGNRPDGGKTMRFDGKDDFLRLTDCPDALRVGDGDFAVATWVKYKTRGQDRESGLRQPLLWAYGQGPAAKQFRIEADPETGRLEATVNDGTGPVSVTAARRTDDDAWHHVVFQRRGDRLELAVDGGPAATAPLGPGRPDFRPTGAFTIHLGTQPDYKAFYAGALDDVRIYGRALSGNDTARLRDGSDVTDQERVRLAFDRIR
>NZ_CP024985.1|WP_078950537.1|3843705_3845439_-|fatty-acid--CoA-ligase-family-protein
MTGETGAAVAAAGAGAAGGAAAGDAGAGSGPAAGGCGDVPDPRGDLRWGSIAGLVQDAAARFGEREAVVDGRLRLDYRQLGERVEHAAAACLAAGVEPGDRVAVWAPNTLDWIVCALGAVSAGAVLVPLNTRFKGAEAAYVLQRSRARLLFVTGTFLGTSYVASLRRAAAEGPGTGPLPGLPHLEQVVVLADDAPESFRTWKDFLADGDSVPAEAVRARAEAIPSDAPSDIIYTSGTTGSPKGAVITHAQTLRCYAVWSELAGLREGDRYLIVNPFFHTFGYKAGIIACLMRGATMVPQSVFNVDTVLANVAAERISVLPGPPTLHQSLLDHPQRDHHDLSALRLVVTGAAVVPLQLVERLRAELHIATVLTAYGLSEASGIVTMCRRGDPAEVVSETSGRAIPDTRLRIAAPDGTARPDGTAGEIWVSGHHVMRGYFEDPDATAGAITPDGWLRTGDVGVLDADGNLRITDRIKDMFIVGGFNAYPAEIEQLLGLHPDVADVAVVGVPDPRLGEVGKAYAVRRPGSTLTADDLIAWSRREMANYKVPREVEFVADLPRNASGKVLKTELRSRRRSA
>NZ_CP024985.1|WP_030236493.1|3845635_3846787_+|lipid-transfer-protein
MAATLKDATAIVGIGQTAFAKQLPQSEKELACRAILAALADAGIAPAEVDAFASYTMEETDEVEVAKAIGAGDVTFFSKVGYGGGGSCATVGHLAAAVATGQATVGVAWRSRKRGSGPRPWKNTAVQLPTPGQWTRPFGLLRPADEIGMLARRYMHEYGATRDHLFNVAMACRNRANENPAAMMYERPLTREMYMTSRMISDPLCLFDNCLETDGALACVIVSAERARDCRQKPVYVHSVAQGLPAQHHGMVNYWNDDPLSGPAWTAARHLWKQADFGPQDVDVAQIYDAFTPLIPLSLEGYGFCGRGEGAAFTEGGALEMGGRLPINTGGGGLSEAYVHGFNLINEGVKQLRGISTAQVPDAATCLVTAGEGVPTSAILLRA
>NZ_CP024985.1|WP_030236495.1|3846797_3847250_+|hypothetical-protein
MTTTAPADGLLLPVPDEDGAPFWEYAARGELRIQACAACGRLRFPPRPCCPHCQSFESEWRPMSGRGRIWSYVRPHPPLLPAYAAQAPYNVILVELAEAPHIRLAGNLVTSADAPLDSVDPARLRIGAKVQVVFAETGGVTVPRWILEKA
>NZ_CP024985.1|WP_030236498.1|3847246_3848023_+|enoyl-CoA-hydratase/isomerase-family-protein
MTVRVEREKEAGVAVVTLDREHRHNAVDLDTAAELSAVWREFRSDEEVRAVVLTGAGTAAFCTGIDRSARVPQPASPYSVDDPLLTIGPKSCDLWKPVIAAVNGMACGGAFYLLGEAEFIVSSTEATYFDPHTSYGMVSAYEAVYMAQRMPFGEVARMSLMGTAERLSARRAHEIGLVSELAEPGELLEAALRSARTLAGFPTEAVQGTVRALWSAKRAALAQALDQAPALIALGNLPPERQPELFGSRRAGAGFRLR
>NZ_CP024985.1|WP_051841266.1|3848023_3848650_-|hypothetical-protein
MLAGTARRVRFGTVLAVVVLSLTGFSTHGGSSGSGSGGGCSSSKSSGTAKSSGKSSSKTTKKSYGGTDATPAASPSPTGPPATTTLISCGDVTDPSTTVEVTSLLGRAATFEVSMYREEAGGAVIETTSGRIALPAHGTGRTVIAMKNRARADAVAACRISAVHVVPDASATPGATPSPAPGTDRSGSKSTPKPGPKATGKAAATSRP
>NZ_CP024985.1|WP_030236503.1|3848920_3849364_+|SRPBCC-domain-containing-protein
MRTIATEITIDASPEEVWATLIDLPRYCVWNPYIRQAVGEAVPGTRLELMAYPESGKPATFRPTVLLVARNVEFRWAHRLPVRGLFDRLHYFRLAEGPNRTTRLEHGERFRGLLVPFRTKTLNATARNLTRMNEALRTRVESARSTP
>NZ_CP024985.1|WP_030236507.1|3849375_3850191_-|class-I-SAM-dependent-methyltransferase
MPPYSVGPEIIAFYSETIDESDRLSTSADGVLEMVRTQELLRRHLPAAPARIIDIGAGPGAHARWLVEDGYAVDLVDPVPRHVEEATAAGLHSVIGDARALTADDDTYDVALVLGPLYHLIDHGDRIRALREAARVVRPGGTVAAAAIGRYASLFEHVATTRLAIDAVRDAVADVLVSGIHEAGRKGFTSAYFHTGESLHGEMREAGLRTPVVYGVEGPAWAALKAAEQHSGDGLAGSKLFDAALTAARLAEPHPDLLAASSHMLAVATVP
>NZ_CP024985.1|WP_051841267.1|3850277_3851048_+|GntR-family-transcriptional-regulator
MPLLKYEHIAESLRRRVADGEFGPGDLLPSSRDLCEQWAVSRATAIKAMEVLRADGLVVPHQGRGFVVTQAPLARPAGGRGTGTSRLQGAAPYRRLGTPEMLVPPSHVADALGLAPGLRALHRARLILAEDGGPHSHVAAWFPPEIADACPRLHQNGPIAEGTTHYVRRTTGRLPVSGTDTTSVRLATTAEAELLQVKRPCAVAVVLHTAHDAAGGVLVCEEGVTPEGLWERTDNYAMGQGGVTGPVHRSNLSMHA

Crispr_ID: NZ_CP024985_16

• CRISPR_ID: NZ_CP024985_16
• CRISPR_location: 4022347-4022427
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_16

Consensus_repeat	Method
CAGCCCCGCCGGCGATTGAGGCGCGGGG	CRISPRCasFinder

spacers of NZ_CP024985_16

>16.1|4022375|25|NZ_CP024985|CRISPRCasFinder
TCCGGGGCGGCGCCCCAGGATCCTT

CRISPR arrays and Neighbor proteins around NZ_CP024985_16

CRISPR arrays

The CRISPR arrays of NZ_CP024985_16

>merge|NZ_CP024985|16|4022347-4022427|CRISPRCasFinder
CAGCCCCGCCGGCGATTGAGGCGCGGGGTCCGGGGCGGCGCCCCAGGATCCTTCAGCCCCGCCGGCGATTGAGGCGCCGGG

>NZ_CP024985|16|17|4022347-4022427|CRISPRCasFinder
CAGCCCCGCCGGCGATTGAGGCGCGGGG	TCCGGGGCGGCGCCCCAGGATCCTT
CAGCCCCGCCGGCGATTGAGGCGCCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030232435.1|4023033_4023609_+|TerD-family-protein	unknown	unknown	gnl|CDD|376767
NZ_CP024985.1|WP_030232421.1|4027746_4028370_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP024985.1|WP_030232427.1|4025745_4026288_-|heme-binding-protein	unknown	unknown	gnl|CDD|377163
NZ_CP024985.1|WP_030232443.1|4019614_4021393_-|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NZ_CP024985.1|WP_030232455.1|4015363_4016296_+|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP024985.1|WP_030232450.1|4017548_4018466_+|1-phosphofructokinase-family-hexose-kinase	unknown	unknown	gnl|CDD|274464
NZ_CP024985.1|WP_030232432.1|4023677_4024193_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP024985.1|WP_030232446.1|4018508_4019546_-|carbohydrate-binding-protein	unknown	unknown	gnl|CDD|271149
NZ_CP024985.1|WP_063760320.1|4026610_4027750_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP024985.1|WP_100661295.1|4013850_4015137_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270452
NZ_CP024985.1|WP_078950414.1|4028366_4029620_+|M4-family-metallopeptidase	unknown	unknown	gnl|CDD|341060
NZ_CP024985.1|WP_030232414.1|4030287_4030977_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP024985.1|WP_030232416.1|4029667_4030171_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037687640.1|4011957_4012581_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367243
NZ_CP024985.1|WP_030232460.1|4012612_4013470_-|trehalose-phosphatase	unknown	unknown	gnl|CDD|319767
NZ_CP024985.1|WP_078950415.1|4021744_4022329_+|flavin-reductase	unknown	unknown	gnl|CDD|214900
NZ_CP024985.1|WP_167456828.1|4024205_4025657_-|M1-family-metallopeptidase	unknown	unknown	gnl|CDD|341066
NZ_CP024985.1|WP_030232453.1|4016295_4017447_+|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl|CDD|238434
NZ_CP024985.1|WP_030232458.1|4013525_4013762_-|DUF3263-domain-containing-protein	unknown	unknown	gnl|CDD|378688
NZ_CP024985.1|WP_030232438.1|4022445_4022871_-|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|181730

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030232435.1|4023033_4023609_+|TerD-family-protein	gnl|CDD|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	5.2371e-115
NZ_CP024985.1|WP_030232421.1|4027746_4028370_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.43655e-64
NZ_CP024985.1|WP_030232427.1|4025745_4026288_-|heme-binding-protein	gnl|CDD|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	1.01533e-26
NZ_CP024985.1|WP_030232443.1|4019614_4021393_-|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.76175e-42
NZ_CP024985.1|WP_030232455.1|4015363_4016296_+|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.38202e-59
NZ_CP024985.1|WP_030232450.1|4017548_4018466_+|1-phosphofructokinase-family-hexose-kinase	gnl|CDD|274464	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family. This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.	9.31116e-103
NZ_CP024985.1|WP_030232432.1|4023677_4024193_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.000983627
NZ_CP024985.1|WP_030232446.1|4018508_4019546_-|carbohydrate-binding-protein	gnl|CDD|271149	cd04083, CBM35_Lmo2446-like, Carbohydrate Binding Module 35 (CBM35) domains similar to Lmo2446. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes. Some CBM35 domains belonging to this family are appended to glycoside hydrolase (GH) family domains, including glycoside hydrolase family 31 (GH31), for example the CBM35 domain of Lmo2446, an uncharacterized protein from Listeria monocytogenes EGD-e. These CBM35s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. GH31 has a wide range of hydrolytic activities such as alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, or alpha-1,4-glucan lyase, cleaving a terminal carbohydrate moiety from a substrate that may be a starch or a glycoprotein. Most characterized GH31 enzymes are alpha-glucosidases.	9.09905e-16
NZ_CP024985.1|WP_063760320.1|4026610_4027750_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.1945e-51
NZ_CP024985.1|WP_100661295.1|4013850_4015137_-|extracellular-solute-binding-protein	gnl|CDD|270452	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold. This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.41418e-52
NZ_CP024985.1|WP_078950414.1|4028366_4029620_+|M4-family-metallopeptidase	gnl|CDD|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	7.04269e-90
NZ_CP024985.1|WP_030232414.1|4030287_4030977_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.61909e-19
NZ_CP024985.1|WP_037687640.1|4011957_4012581_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	4.33863e-15
NZ_CP024985.1|WP_030232460.1|4012612_4013470_-|trehalose-phosphatase	gnl|CDD|319767	cd01627, HAD_TPP, trehalose-phosphate phosphatase similar to Escherichia coli trehalose-6-phosphate phosphatase OtsB and Saccharomyces cerevisiae trehalose-phosphatase TPS2. Trehalose biosynthesis in bacteria is known through three pathways - OtsAB, TreYZ and TreS. The OtsAB pathway, also known as the trehalose 6-phosphate synthase (TSP)/ Trehalose-6-phosphate phosphatase (TPP) pathway, is the most common route known to be involved in the stress response of Escherichia coli. It involves converting glucose-6-phosphate and UDP-glucose to form trehalose-6-phosphate (T6P), catalyzed by TPS, the product of the otsA gene, this step is followed by the dephosphorylation of T6P to yield trehalose and inorganic phosphate, catalyzed by a specific TPP, the product of otsB gene. This OtsAB (or TSP/TPP) pathway, is also the most common route known to be involved in the stress response of yeast In Saccharomyces cerevisiae, the corresponding enzymes, TPS1p and TPS2p, form a multimeric synthase complex together with additional regulatory subunits encoded by Tsl1 and Tps3. Trehalose is a common disaccharide accumulated by organisms as a reservation of carbohydrate and in response to unfavorable growth conditions. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.13088e-30
NZ_CP024985.1|WP_078950415.1|4021744_4022329_+|flavin-reductase	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	3.50453e-44
NZ_CP024985.1|WP_167456828.1|4024205_4025657_-|M1-family-metallopeptidase	gnl|CDD|341066	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains mostly bacterial and some archaeal M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	1.32329e-175
NZ_CP024985.1|WP_030232453.1|4016295_4017447_+|N-acetylglucosamine-6-phosphate-deacetylase	gnl|CDD|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	1.80443e-154
NZ_CP024985.1|WP_030232458.1|4013525_4013762_-|DUF3263-domain-containing-protein	gnl|CDD|378688	pfam11662, DUF3263, Protein of unknown function (DUF3263). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.48851e-25
NZ_CP024985.1|WP_030232438.1|4022445_4022871_-|aminoacyl-tRNA-hydrolase	gnl|CDD|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	1.41671e-56

Protein sequences

>NZ_CP024985.1|WP_078950415.1|4021744_4022329_+|flavin-reductase
MAPSPPPPPTPVAPEPSATPHPEGVSNDEFRAAMSRLAAGVCLITAHEPPSTADGPRGEDVGMTATAFMSVSLDPPLVLVSLREGSRMDDLLAEQPLWAVSVLADGQLQVAGRFAMKNRISDRLLFEGLPTVRGAVSGALLLSGALATLECRTESRVEAGDHTLVIGRVLTATLPTPDAPPLTYFRGRYRHLAP
>NZ_CP024985.1|WP_030232443.1|4019614_4021393_-|diguanylate-cyclase
METESEPYVRLATLRQLHQVVAELNTARSLADTLQTVVDGIVRGLGYELACVNLVRPDGDLVVAAFAGDPAAEALITGRVGSRPSWERRLAMGEDWDGLRFIPHTEGWVLIEDDVPQWHTDGPDPRFEDEWHPEDRLYAPMYATGGELLGVISVDRPRNGRRPGAWGREALQMYAFQAAIAISNARLRANMQRALVRLEREQQALRASEESFRQAFEYAPSGMAIAEMGGDQHGRLLRTNDALCRLLGRPASVLRRYSFSDLVHPEDIGTLLRTSAEGGRAELRLGRRDGTYVWVSLRNSVVADAADGPRFLLTHVEDIEERKRHELQLAHRASHDSLTGLPNSAELRSRLGARLCRRPQSVRATAVEALDAAFETRPEAGGAGEHGFRPDGHDGSDYGYPAAGAGAGAGAGAGTGAAAGSGAAPGTDPFEFSGAFTSHADGPYDHHVHIVAPATDVDDGTKGLAVLFCDLDGFKSINDRFGHHTGDAVLIEVARRLTTCVRDGDTVARLGGDEFVVLADGLGAADAADLAVRLRNAIIPPIRVDGRAVRVGASFGIGWASCGMSADEVLRSADQRMYIEKRSRSKAHRRAG
>NZ_CP024985.1|WP_030232446.1|4018508_4019546_-|carbohydrate-binding-protein
MTTPAHNGPHGGANQPEDDDPFGYLYADGQAAGATPPGQGGGYGYPGPAVGGPPGAQPGVPRTSYNQVRTVGERTYGGQRGAVPPQQQAPAYQAQYQAPEALQAGGYGVPAQQQHTQQAPLPGGRGGHGGGGGSSRKGLLIAAVAVVAAVAVGISAAVIFGKKGEDKKGANQASSQSPKPSAPQQNPGATDPSGSPEPSQSPLPKGEAAGAGMALTGGAVLQSTVQGSKSSGGQYVGNFNTPGAALTWTVDVPEAGDYTLFVNYAVPGKDAKTTLTVNGQSPNQSLNLANFAKADAGAWDKGWTRTFAWITLKKGSNAMRISCEAGNQCDVIFDQLRLGQGHTKG
>NZ_CP024985.1|WP_030232450.1|4017548_4018466_+|1-phosphofructokinase-family-hexose-kinase
MILTVTLNTALDVTHRVPRLLPHASHRVTGVAERPGGKGLNVARVLGALGHPVTATGFAGGPAGTLVRELLADCPGVTDALVPCAGTTRRTLAVVDETTGDTTQFNEPGPQITAGEWSAFLARYAELVSGARAVALCGSLPPGVPVGAYATLVRTARTAGVPVLLDTSGEALRRGVAARPEIIKPNSAELAELTGSREPLPATRDARRRGAHAVVTSLGPGGLLAATPDGTWQAAPPRALSGNPTGAGDSAVAGLLSALAEGLDWPARLTRAVALSAATVHAPTAGEFDPRTYEEVRGSVKVTPL
>NZ_CP024985.1|WP_030232453.1|4016295_4017447_+|N-acetylglucosamine-6-phosphate-deacetylase
MSGSAHSTVLSGARVVLPTGTVAGGRVIVERDRIAGSAHEGAEIVDLSGHWIVPGFVDVHNHGGGGASFTSGTAEEVLRGVRTHREHGTTTLVASTVTGDLDELARRAALLAELTQQGEIAGVHFEGPFINPCRKGAHKADLLRDPDPAEVRKLVDAAHGTARMFTLATELPGGLDSVRLLAEHGVIAAIGHTDSTYDQTRQAIDAGATVATHLYNAMPGLEHRAPGPIAALLEDERVTVELINDGTHLHPAMLELAFHHAGAHRVALITDAMDAAGFGDGTYHLGPLEVEVKDGVARLVEGGSIAGSTLTLDTAFKRSVTVDRLPVESVVQAISANPAKLLGRYDEVGSLEPGKYADLVVLDAAFDLKGVMRRGEWIVSPLS
>NZ_CP024985.1|WP_030232455.1|4015363_4016296_+|ROK-family-protein
MKHVIALDVGGTGMKAALIARDGNLLHEVRRATGRERGPEAVVETILDFAAELLRLGAERFGTTASAAGVAVPGIVDAERGTAVYAANLGWRDVPLRALLGARLGGLPVALGHDVRTGGLAEGRIGAGRGTDRFLFVPLGTGIAGAIGIAGRIEAGAHGYAGEIGHIVVRPGGPACGCGQHGCLETLASASAVSRAWAAASGDPGADAADCAKAVESGDTRAREVWLTAIGALADGLVTAITLLDPSRVIIGGGLAEAGETLFTPLRAAVEERVTFQRLPEIVPAALGDTAGCLGAGLLAWDLLATEVPA
>NZ_CP024985.1|WP_100661295.1|4013850_4015137_-|extracellular-solute-binding-protein
MSLAATGAALCLTATLTGCGTVSGLSGDNEVTLRVVAADYGDNPQNSSATYWKGLASSFEKDNPGVHVEVSVYSWSEVDAKVAEMVKAGKAPDIAQIGAYADYAEAGKLYTADELLSVNTEADFLAPLADAGKVKRVQYGMPFVASTRLLFYNTKLLGDAGVIPKDGSAPWQPKSWADLEAAAKKLKGAGVPTPFALPLGREEAQAESMMWMLAGGGGYTDNEEAYAIDSPENVKSFEFLRDKMVGQGLTGPVEPGKLDRQAAFDAFTRGEVGMLNGHPTLIKQAAGKGVKFGMVPMPTADGADHSAMGVADWVMAFKNGHRKEAGKFLDLLYSAKNVTAFTNTYDLLPVTTSGYRAMDASTGGSAAQLKTFLAALPTSRLYPVGKKSWAGVSEDIKQNIGQVVQPGGQPAKVLENIATSARKADGDH
>NZ_CP024985.1|WP_030232458.1|4013525_4013762_-|DUF3263-domain-containing-protein
MTDDGRLTATEAAVLAYEGRTWPGPGAKERAIREGLGLTPVRYYQLLNALMDDPRALEHAPGTVNRLRRIREAQRARR
>NZ_CP024985.1|WP_030232460.1|4012612_4013470_-|trehalose-phosphatase
MGSHPHDLPMPVPATAAGREGLEALLRAPRSAVVALDFDGTLADIVPDPDQARAHPDAVPALAALAPQVAAVAVVTGRPAGVAVRYGGFAGVPGLEHLVVLGHYGAERWDAVTGIVHAPAEHPGVAAVRAELPGFLDAIGAWRGTWIEEKGRALAVHTRRAEDPEAAFSALREPLAELAARHGLMVEPGRAVLELRPPGMDKGVALTEFLEERRAEAVLYAGDDLGDLAAFSAVEKRRADGLPGLLVCSGSAEVPELAARADLVLPGPGAVAAFLATLAGALRTA
>NZ_CP024985.1|WP_037687640.1|4011957_4012581_+|TetR/AcrR-family-transcriptional-regulator
MKLTKERIIDAGMAEFAESGYHGLSMRRVAQRLDAKAGSLYYHVPSKGVLVRLMADRVARQAYDAGTAALAALDPGAGWRERVEAQALTLRAVIRRHAGGAVMFADSPKVLSDGALSVMERLLETLRAAGVPEGDCAVGADALLSHLTGFVLQEQSESPEAPVGPEDVAALLERFPLTVAAASAHGEDEKFLRSVRLICAGLATLIP
>NZ_CP024985.1|WP_030232438.1|4022445_4022871_-|aminoacyl-tRNA-hydrolase
MPGPYVIRGSVVLPEAELAWRFSRSSGPGGQHVNTSDSRVELLFDVAATKALPDVWKERALERLASRLVDGVVTVRASEHRSQFRNREMALVRLAALLAEATAPPPKARRATKIPRGINERRLREKKARAETKRGRTGRDW
>NZ_CP024985.1|WP_030232435.1|4023033_4023609_+|TerD-family-protein
MAVSLSKGGNVSLTKEAPGLSAVTVGLGWDVRTTTGVDFDLDASAIAVNATGKVVSDGHFVFFNNKSTPDQTIVHTGDNRTGEGSGDDESINVNLAGLSADVDKIVFPVSIYDAESRSQNFGQVRNAYIRVVNQAGGAEIARYDLSEDAATETAMVFGELYRNGAEWKFRAVGQGYASGLTGIAQDFGVNV
>NZ_CP024985.1|WP_030232432.1|4023677_4024193_+|GNAT-family-N-acetyltransferase
MILQPLVPVDGALPGPALTEIAALYATNRAFFELSGDFPDPARITVEQVATALADELAVDSAEVLLARSAGRLVGLAVTLAHHPDPASGDPDPWIGLLLIDSTAHREGHGRTVAGLIEDRFRTAGRAGVRLAVLEDNAAGLAFWQAQGYTLLRRAKDRDRGRPVRVMRKEL
>NZ_CP024985.1|WP_167456828.1|4024205_4025657_-|M1-family-metallopeptidase
MEPVEHPALPGRTGLTRLAAPAVAALLSLAVLATGCTGATVQGRPGASGLRDPYFPRAGNGGYQVEHYDLDLAYDPADGLLHATAVITARAEQGLSSFNLDLSGLKVESVDVQGTGARYNRTGNELTVRPAKDLKKGEVFRTEIDYGGRPKPVVDPDGSKEGWIAGGDGAVAVGEPVGSMGWFPGNHHPSDKATYDITVTVPHGYEAVSNGELRSRKEVADGQTEFAWHSPEPMASYLATVAIGRFKVTTGRTPSGVPVYDAVAPGEAAGSEAALGRLPQIVDWGTEKFGPYPFGSVGSIVMPAQTLTYALETQTKPVYSGAPDEELVLHELAHQWFGDSVSPKSWKDMWLNEGFATYAEWLWSEEHGGVSAQRRFDAFLAGDTSVDPHADGDWAAFPPASPPGPEHISDDPVYYRGAMVLHRIRQEVGDPAFFGLLRGWAADHRHGNASTADFTAYAQRRTGHDLKKVWDVWLYGEDRPTAP
>NZ_CP024985.1|WP_030232427.1|4025745_4026288_-|heme-binding-protein
MNTRTRVLTGTALAVALGAGTFGAVSASATPAPVQAAAKKDDDRNFTTSTHLTVDAATRAAQAALRAAEKENQKVTVAVVDRNGNTVVTLRGDGAGPQSYESAQRKAFTAVSWNAPTSVLAGRLAQTPNLKDIPGTLFLAGGSPVQANGAPVAGIGVAGAPSGDLDEKFAKAGADALGDK
>NZ_CP024985.1|WP_063760320.1|4026610_4027750_+|sensor-histidine-kinase
MHAAFFLLLGASVARFLLRHPGEPRTPWVIALSIALALLYVLGPAVGATRTLPATAPPTPLRRRLWLGLVVATWVVLVVLAPSFAWCAVPLFFTALRTLPPRAAVVLVALLTVFVVAAQLRLSTAFDPNLLVAPPAVAALATAVFVHMERQAQEQRALIDDLIRTRRELAATERREGTLAERQRLSMEIHDTLAQHLSSQQMLLQAADRTWESDPGTARAHVRTATDITARGLAEARRLVHDLAPPELENGAGLAEALRALDAGPGIEVRFHLEGAPVPLPDRAESALLRIAQGALANVREHAGARTAALTLSFLGDQVVLDIADDGAGFAETRSASGRGHGLPAMRARVRQLGGTLTIESTPGEGTVLSAVIPLEPTR
>NZ_CP024985.1|WP_030232421.1|4027746_4028370_+|response-regulator-transcription-factor
MTTILLCDDHVVVRAGLLALLGSEPDIEVLGEAGSGEEAVALAAKLRPDVVLMDLQLGEGIDGVEATRRITALPQPPHVLVLTTYDTDADITRAIGAGATGYLLKAERPEELFAAIHSAAAGRTTLSAPVASRVMAHMRGTRPTLTDRELDILGQLARGLGNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLPS
>NZ_CP024985.1|WP_078950414.1|4028366_4029620_+|M4-family-metallopeptidase
MTGSGQEGPVFGQPGPGSRRRPAGPAPSDGTLTRATPTREGAPVPHPTPSRRARLATAVLLGAAVALTTGTATASTTPTTAPGTGTGTGTGTGTGTGTGTGQYSGTVPLGTTPSGTTHQLRDPSRGNQRTLDALNQTSGPGVLFTDADDVWGTGLPSNRQTAAVDVHYATAVTWDFYRATFNRSGVRGDGAATTSRVHYGTDYGGAFWDASCACVSYGDGTTPGRPPTSLDIVGHELAHGLIGSTANFAATGEPGALGEGTADILATAGEFFAENKADVGDYLLGERVYDGPLRRMDRPSADGVSRDYWSADMGGLDPHAASGPARHFYYLLAEGSGPKEINGVAYDSPTYDGSKLLGIGRDRATRIWYRALTLHMRSSTDYAAARTATIQSAIELYGASSAEAIRVAAAWKAVNVG
>NZ_CP024985.1|WP_030232416.1|4029667_4030171_+|hypothetical-protein
MLDIGYSLSRRFPDPPQTDYRSADVRTLRHDLFCGDVYLADTVKDTEVSTAWGWVPVLDFAWALCDIVEQLDEDPRGSRSANRQYAELDFTESADRMLFERRFGWVDIEADWMDPEEPPLTFSHRLLRREARDFLHDLIADLIDMHDGLADNPIIWTLQSRFPRVPA
>NZ_CP024985.1|WP_030232414.1|4030287_4030977_-|pentapeptide-repeat-containing-protein
MVRSERVRGRAGGAVRAARRAEVRLPGLVAWEGGGLEPDGDYDGLEFADVDLAGQEGVGARFMDCALRRCRLDGAGLAKARILDSVLEGVRGVGTDLAGASLRDVELVEARLGGAQLHGAVLERVLVRGGKIDYLNLRTARLKDVVFDGCVLVEPDFGGAVLERVEFRGCVVRGADFTGARMTDVDLRAASELGIARGVEALAGAVISPAQLFDLAPALAAQLGLRVEG

Crispr_ID: NZ_CP024985_17

• CRISPR_ID: NZ_CP024985_17
• CRISPR_location: 4076631-4076849
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP024985_17

Consensus_repeat	Method
GGGCGGCAGGTACGCCGTCCGCTC	CRISPRCasFinder

spacers of NZ_CP024985_17

>17.1|4076655|27|NZ_CP024985|CRISPRCasFinder
CGCCGCCGCGTCGGGGGCGGGCGGCTG
>17.2|4076706|18|NZ_CP024985|CRISPRCasFinder
GGCGGCGGCCTCCGTCAC
>17.3|4076748|36|NZ_CP024985|CRISPRCasFinder
GGTGTCCCAGGCCTGCGGCTGCGCCTGCGCCTGGAC
>17.4|4076808|18|NZ_CP024985|CRISPRCasFinder
GGCGGCGCTGTCGCGTAC

CRISPR arrays and Neighbor proteins around NZ_CP024985_17

CRISPR arrays

The CRISPR arrays of NZ_CP024985_17

>merge|NZ_CP024985|17|4076631-4076849|CRISPRCasFinder
GGGCGGCAGGTACGCCGTCCGCTCCGCCGCCGCGTCGGGGGCGGGCGGCTGGGGCGGCAGGTAGGCCGTCCGCTCGGCGGCGGCCTCCGTCACCGGCGGCAGGTAGGCCGTCCGCTCGGTGTCCCAGGCCTGCGGCTGCGCCTGCGCCTGGACGGGGGGCAGGTACGCGGTCTGCTCGGCGGCGCTGTCGCGTACCGGCGGCAGGTACGCCGTCTCGGC

>NZ_CP024985|17|18|4076631-4076849|CRISPRCasFinder
GGGCGGCAGGTACGCCGTCCGCTC	CGCCGCCGCGTCGGGGGCGGGCGGCTG
GGGCGGCAGGTAGGCCGTCCGCTC	GGCGGCGGCCTCCGTCAC
CGGCGGCAGGTAGGCCGTCCGCTC	GGTGTCCCAGGCCTGCGGCTGCGCCTGCGCCTGGAC
GGGGGGCAGGTACGCGGTCTGCTC	GGCGGCGCTGTCGCGTAC
CGGCGGCAGGTACGCCGTCTCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030232265.1|4079120_4080143_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP024985.1|WP_030232275.1|4074961_4075675_-|DUF2993-domain-containing-protein	unknown	unknown	gnl|CDD|378597
NZ_CP024985.1|WP_030232252.1|4083884_4084763_-|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl|CDD|176528
NZ_CP024985.1|WP_030232309.1|4069479_4069905_+|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl|CDD|235383
NZ_CP024985.1|WP_078950409.1|4072910_4073246_-|DUF3099-domain-containing-protein	unknown	unknown	gnl|CDD|378630
NZ_CP024985.1|WP_030232314.1|4067355_4068600_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|234945
NZ_CP024985.1|WP_030232247.1|4085546_4086326_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP024985.1|WP_030232284.1|4073664_4074513_-|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NZ_CP024985.1|WP_030232250.1|4084824_4085412_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NZ_CP024985.1|WP_030232255.1|4082468_4083905_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP024985.1|WP_030232259.1|4081737_4082472_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP024985.1|WP_030232304.1|4070922_4071351_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NZ_CP024985.1|WP_030232306.1|4069923_4070892_-|folate-binding-protein-YgfZ	unknown	unknown	gnl|CDD|223431
NZ_CP024985.1|WP_030232270.1|4077515_4077770_-|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340560
NZ_CP024985.1|WP_030232268.1|4078244_4079096_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP024985.1|WP_030030422.1|4073299_4073590_-|DUF1416-domain-containing-protein	unknown	unknown	gnl|CDD|377793
NZ_CP024985.1|WP_100661296.1|4080366_4081542_+|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|273938
NZ_CP024985.1|WP_100660904.1|4068756_4069296_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_051841082.1|4086420_4088235_-|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl|CDD|277357
NZ_CP024985.1|WP_030232302.1|4071428_4072001_-|FABP-family-protein	unknown	unknown	gnl|CDD|378046

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030232265.1|4079120_4080143_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.34937e-98
NZ_CP024985.1|WP_030232309.1|4069479_4069905_+|D-tyrosyl-tRNA(Tyr)-deacylase	gnl|CDD|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	7.71718e-81
NZ_CP024985.1|WP_030232275.1|4074961_4075675_-|DUF2993-domain-containing-protein	gnl|CDD|378597	pfam11209, DUF2993, Protein of unknown function (DUF2993). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	7.14001e-21
NZ_CP024985.1|WP_030232252.1|4083884_4084763_-|phosphatidylinositol-specific-phospholipase-C	gnl|CDD|176528	cd08586, PI-PLCc_BcPLC_like, Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins. This subfamily corresponds to the catalytic domain present in Bacillus cereus phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) and its sequence homologs found in bacteria and eukaryota. Bacterial PI-PLCs participate in Ca2+-independent PI metabolism, hydrolyzing the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. Bacterial PI-PLCs contain a single TIM-barrel type catalytic domain. Their catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This family also includes some uncharacterized eukaryotic homologs, which contains a single TIM-barrel type catalytic domain, X domain. They are similar to bacterial PI-PLCs, and distinct from typical eukaryotic PI-PLCs, which have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains, and strictly require Ca2+ for their catalytic activities. The prototype of this family is Bacillus cereus PI-PLC, which has a moderate thermal stability and is active as a monomer.	3.7701e-88
NZ_CP024985.1|WP_030232268.1|4078244_4079096_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.20222e-48
NZ_CP024985.1|WP_078950409.1|4072910_4073246_-|DUF3099-domain-containing-protein	gnl|CDD|378630	pfam11298, DUF3099, Protein of unknown function (DUF3099). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	0.000668653
NZ_CP024985.1|WP_030232314.1|4067355_4068600_-|GNAT-family-N-acetyltransferase	gnl|CDD|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	1.28105e-136
NZ_CP024985.1|WP_030232284.1|4073664_4074513_-|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	5.05707e-100
NZ_CP024985.1|WP_030232247.1|4085546_4086326_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.3726e-25
NZ_CP024985.1|WP_030232255.1|4082468_4083905_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.14129e-48
NZ_CP024985.1|WP_030232259.1|4081737_4082472_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.68057e-91
NZ_CP024985.1|WP_030232304.1|4070922_4071351_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	2.76647e-33
NZ_CP024985.1|WP_030232306.1|4069923_4070892_-|folate-binding-protein-YgfZ	gnl|CDD|223431	COG0354, COG0354, Predicted aminomethyltransferase related to GcvT [General function prediction only].	7.95525e-55
NZ_CP024985.1|WP_030232270.1|4077515_4077770_-|MoaD/ThiS-family-protein	gnl|CDD|340560	cd17040, Ubl_MoaD_like, ubiquitin-like (Ubl) domain found in a group of small sulfide carrier proteins. Ubiquitin-like (Ubl) domain found in a group of small sulfide carrier proteins This family includes ThiS, MoaD, CysO, QbsE, and their homologs, which are structurally homologous to ubiquitin (Ub) and may function as the sulfide donor for the biosynthesis of thiamin, molybdopterin, cysteine, thioquinolobactin, and other sulfur-containing natural products. Ub is a protein modifier in eukaryotes that is involved in various cellular processes, including transcriptional regulation, cell cycle control, and DNA repair. Ubiquitination is comprised of a cascade of E1, E2 and E3 enzymes that results in a covalent bond between the C-terminus of Ub and the epsilon-amino group of a substrate lysine. Like Ub, small sulfide carrier proteins in this family are adenylated at a diglycyl C-terminus by specific activating proteins. The adenylated C-terminus is subsequently converted to a thiocarboxylate, serving as the sulfide source. Those activating proteins are diverse and show little sequence similarity. This family also includes the small archaeal modifier protein (SAMP), including SAMP1, SAMP2 and SAMP3, which are Ub-like proteins that function as protein modifiers and are required for the production of sulfur-containing biomolecules in the archaeon Haloferax volcanii. SAMP1 and SAMP2 are involved in sulfur transfer during molybdenum cofactor biosynthesis and tRNA thiolation much like MoaD and Urm1, respectively. They can form covalent conjugates with their protein targets through an isopeptide linkage via their C-terminal diglycine motif in a streamlined archaeal E1-dependent pathway. SAMP2 also forms homo-conjugates through the intermolecular isopeptide bond between the C-terminal Gly and the Lys58 side chain, a feature that likely resembles polyubiquitination. SAMP3 conjugates are dependent on the Ub-activating E1 enzyme homolog of archaea (UbaA) for synthesis and are cleaved by the JAMM/MPN+ domain metalloprotease HvJAMM1.	8.28972e-10
NZ_CP024985.1|WP_030030422.1|4073299_4073590_-|DUF1416-domain-containing-protein	gnl|CDD|377793	pfam07210, DUF1416, Protein of unknown function (DUF1416). This family consists of several hypothetical bacterial proteins of around 100 residues in length. Members of this family appear to be Actinomycete specific. The function of this family is unknown.	3.09646e-35
NZ_CP024985.1|WP_100661296.1|4080366_4081542_+|trypsin-like-serine-protease	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	4.38798e-66
NZ_CP024985.1|WP_030232250.1|4084824_4085412_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.19658e-11
NZ_CP024985.1|WP_051841082.1|4086420_4088235_-|bifunctional-metallophosphatase/5'-nucleotidase	gnl|CDD|277357	cd07412, MPP_YhcR_N, Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain. YhcR is a Bacillus subtilis sugar-nonspecific endonuclease. It cleaves endonucleolytically to yield nucleotide 3'-monophosphate products, similar to Staphylococcus aureus micrococcal nuclease. YhcR appears to be located in the cell wall, and is thought to be a substrate for a Bacillus subtilis sortase. YhcR is the major calcium-activated nuclease of B. subtilis. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.01415e-123
NZ_CP024985.1|WP_030232302.1|4071428_4072001_-|FABP-family-protein	gnl|CDD|378046	pfam08768, DUF1794, Domain of unknown function (DUF1794). This domain forms a beta barrel structure but the function is unknown. The GO annotation for this protein indicates that the protein has a function in nematode larval development and has a positive regulation on growth rate.	4.45498e-62

Protein sequences

>NZ_CP024985.1|WP_030232275.1|4074961_4075675_-|DUF2993-domain-containing-protein
MRFLRFVLIVGVVLGALFVGADRWAVGYAENRLAERLQARQGLAGSVEVNIHGFPFLTQALSHDLERVDLKLKGVDAAADGRKTRLTELDASFREVKLNGSYSGGTAKRAEGSALISYADLTEASQSGVNLTYGGAPGKVKVTATVEFLGKRLTRDVVSTVTLVDANDGKNGKVVRVRAESVPGEGIPGVESAVRKRTDFDRRIDAGLPSGLALTGLTSDAEGVHVTLSGTDVVLAG
>NZ_CP024985.1|WP_030232284.1|4073664_4074513_-|sulfurtransferase
MSRSDVLVDADWVEAHLNDANVVIVEVDEDTSAYDKNHITNAVRIDWKSDLQDPVRRDFVDQEGFEKLLSAKGISNDDTVVLYGGNNNWFASYAYWYFKLYGHQDVRLLDGGRKKWELDSRDLVDGKDVPNRPATQYKAKPQDTSIRAFRDDVLAAINVQNLVDVRSPDEFSGKLLAPAHLPQEQSQRPGHVPSARNIPWSKNANDDGTFKSDDELTALYQAEGVDLDTKDTIAYCRIGERSALTWFVLHELLGQENVKNYDGSWTEYGSLVGVPIELGPNK
>NZ_CP024985.1|WP_030030422.1|4073299_4073590_-|DUF1416-domain-containing-protein
MCGAQIGGPDLATLKPGETAIQGQVTKDGEPVSGYVRLLDSTGEFTAEVPTSATGQFRFYAATGSWTLRALVPGAQADRAVVVAEAGGVTDVAIAV
>NZ_CP024985.1|WP_078950409.1|4072910_4073246_-|DUF3099-domain-containing-protein
MDRGAALRAVHSPCPGGGRPYAGDMYARRRRAYFLLMGGCLFLFVSAWSFVRLFSVEAAVALCVVAMVIPPIAAMVANRRGPDDRWWDDPSGDPKSDEWWDELDGKRRHED
>NZ_CP024985.1|WP_030232302.1|4071428_4072001_-|FABP-family-protein
MIQIPSDLNPGLVPLAFLLGNWEGAGVFDFPGEEKCNFGQEVVFSHDGRDFLEYTSHTWVLDAEGNKVRPLESESGYWRIDADRKVEIVMVRDQGVVEVWYGELADQKPQIDVVTDAVARTAASGPYSGGKRLYGYVKSDLMWVGEKATPEVELRPYMSAQLKKVVTPEEIADMARNLPELPEDGIAFFR
>NZ_CP024985.1|WP_030232304.1|4070922_4071351_-|transcriptional-repressor
MATTDWKTDLRQRGYRLTPQRQLVLEAVDALEHATPDEILVEVRKTASGVNISTVYRTLELLEELKLVSHAHLGHGAPTYHLADRHHHIHLVCRDCNEVIEADLDVAAEFTAKLRATFGFDTDMKHFAIFGRCAKCAAQRPR
>NZ_CP024985.1|WP_030232306.1|4069923_4070892_-|folate-binding-protein-YgfZ
MTSSPLLHLSGAVPAEGRDEGVAAHYGELYGEQRALADGRGFVDLSHRGVVTVTGPDRLAWLHLLLTQHVSDLPAGQATEALILSANGHIEHALYLVDDGETVWAHVEPGTQEALIAYLEAMKFFYRVEVADRTDAFAVVHLPAGSIAEVPAEHRVRETAHGRDVFLPREALEDFAAAHGPAAGLLAYEALRVEAHRPRLGLETDHRTIPHELGWLGTAVHLQKGCYRGQETVARVHNLGKPPRRLVFLHLDGSEVLLPPHGAPVRLAADGEDGRQLGFVTTAVRHHELGPIALALVKRNVPVDAPLLAGNTAAAQEVVVAP
>NZ_CP024985.1|WP_030232309.1|4069479_4069905_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRAVVQRVDGASVVVAGETVGEIVGEGLCVLVGVTHDDTPEKAALLARKLWSVRILEAEKSCSDIGAPLLVISQFTLYGDARKGRRPTWNAAAPGPVAEPLVDEVVAQLRALGATVETGRFGADMRVSLTNHGPFTIVIDI
>NZ_CP024985.1|WP_100660904.1|4068756_4069296_-|hypothetical-protein
MPQAAAPAARPPAQRTGDPGPTTPATALGLPELRALRRDAQRDEADLSYVRRLLQGRIDILRAELARRTDPETPVVDRLSEILADAPSSRSASARHVTLGTPHNEEFRLLAAEMLSEVELSDLAARTDAELHDAMGRLVGYEQQVSRRRQQLQRTADDSSAEITRRYREGEAQVDDLLA
>NZ_CP024985.1|WP_030232314.1|4067355_4068600_-|GNAT-family-N-acetyltransferase
MSADVRPIAASELPDWLTTLNTGFLTPATPTESDVAQRAAHSDLARIQGGFDPVTGRCVATFRSFAQELTVPGGATVPCSAVSNVTVLATHRRQGVLTRMMAAELDAAQARGDVLATLIAAEYPIYGRYGFGPAASLAEWEIDVARTGLDRHRPLPADGSRIDLVDAAEARRVGPALHERLRAGAHGTIGRDDRWWDLTTGMAQMSHRPYKQKMFAVYRTADGEVAGLAVYRADDHWTDAKVPQQTLFVTDLIAATPAAERALWHFLCSIDWVLKVRTGYRAPDSLVPDLLPDPRAARLVTAADFLWVRVLDVVRALSARTYAVPGTLVLEVLDPDGPAGGRYRLDAGAGTCARTEEAVDLRLDVSALGALYLGDTSAVRLAELGRVAGERPGAVELADAVFRTARRPWCPDVF
>NZ_CP024985.1|WP_030232270.1|4077515_4077770_-|MoaD/ThiS-family-protein
MATGTIRYWAAAKAAAGTAEEPYSAHTLAEALEAVRERHPGQLTQVLLRCSFLVNDEPVGKRPHEAVPLTEGGTVEVLPPFAGG
>NZ_CP024985.1|WP_030232268.1|4078244_4079096_+|response-regulator-transcription-factor
MSSLLLLTNALQPSTEVLPALGLLLHNVRVAPAEGPALVDTPGADVILVDGRRDLPQVRSLCQLLRSTGPGCPLILVVTEGGLAAVTADWGIDDVLLDTAGPAEVEARLRLATGRQQLGSDDSPMEIRNGDLSVDEATYSAKLKGRVLDLTFKEFELLKYLAQHPGRVFTRAQLLQEVWGYDYFGGTRTVDVHVRRLRAKLGPEHESLIGTVRNVGYRFVTPEKVERAAAEAAERAAAKQAAQQAAAQQAASGAAQGGDRAAAAPRTEESPVTIHSAGRPAQR
>NZ_CP024985.1|WP_030232265.1|4079120_4080143_+|LacI-family-DNA-binding-transcriptional-regulator
MAKVTRDDVARLAGTSTAVVSYVINNGPRPVAPATRERVLAAIKELGYRPDRVAQAMASRRTDLIGMIVPDARQPFFAEMAHAVEQAAAERGKMVLVGNSDYRDEREVHYLRAFLGMRVSGLILVSQGMSERAASEIEAWDARIVLLHERPEAIDDVAVVTDDIGGAQLATRHLLEHGHEYVACIGGVENTPSVGDPVADHVEGWRRAMLEAGRSVEGRLIEAPYNRYDAYTVALEVLARPDRPTAIFCATDDQAIGVLRAARELRIDVPEQLAVAGFDDVKEAALTDPPLTTIASDRPAMARAAVDLVLDDALRVAGSRRERLKQFPSALVIRRSCGCR
>NZ_CP024985.1|WP_100661296.1|4080366_4081542_+|trypsin-like-serine-protease
MAQDTGAGAYPPPPAYPPAAPAPAPGWHEAHQPPVIQGETVPAGGDGDTGGHGGHGGGGWAAWGSAAPAAPAAPAHAARAKRPVALLAAVALAAAVIGGGTAAAVQQFLDHQGSAGGGFSGTNVSQSSNGTVSGVAEQVSPSVVRIDTRTGSGQGTGSGIVITADGEIVTNNHVVSGASEIQVTMSDGKKYAAKTVGTDPDKDLALIKLQGASGLKPAKLGNSDQLRVGDQVVAIGSPDRLTGTVTSGIVSALDRDVNVPKSEQQQSPQRGQGGGWPFSYDGQQFNGNTGSNTTSYKAIQTDASLNPGNSGGALVNLNGEIVGMPSAIYSPSSDSSSAGSVGLGFAIPVNTVKADLDGLRKGGTGGIGDSGNGNGTGSDGSGSGRSGTSWF
>NZ_CP024985.1|WP_030232259.1|4081737_4082472_+|response-regulator-transcription-factor
MNATEGEPQRILVVDDEPAVREALRRSLAFEGYGTRTAVDGLDALDQAATYAPDLIVLDIQMPRMDGLTAARRLRASGSVTPILMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARVRALLRRSSYRAPSAAPESSADVLSFGDLRMDLTTREVTRGHRAVELTRTEFTLLEMFLAHPRQVLTREQILKTVWGFDFEPSSNSLDVYVMYLRRKTEAGGEPRLVHTVRGVGYVLRAGEGGPE
>NZ_CP024985.1|WP_030232255.1|4082468_4083905_+|HAMP-domain-containing-histidine-kinase
MSPTARFHALPLRSRLALLVAVAVAVAVAAVAAVAWVMVRTQLRDQLDRSLMSTNVSAQVARTLREGCVVQPPKPTQQIAGNLNATVQIVLSDGTRCWVGGQPDLPVTGADRQVAADVEAKPVLHDVTTPDGVDMRVYTLQANPAGPAFGVSIAKPLGDVEKPLSTLAWVLLLVSGIGVVGAGAAGLWVARTGLRPVDELTGAVEHIARTEDLTVRIPDEGDDEIARLSRSFNSMTAALASSQERQAQLIADAGHELRTPLTSLRTNIELLARSEETGRAIPPDDRRELLASVKAQMTELAALIGDLQELSRPDAAPHGPLGVVALHETAAAALSRARLRGPELVFTSTLEPWYVRGEAAALERAVVNVLDNAVKFSPPGAAVEVSLRAGELTVRDHGPGIPAEDLPYVFERFWRSPSARALPGSGLGLSIVARTVQRAGGTAVLRAAADGGRGTEAVLRLPGAPTPPPSTASVVPDQ
>NZ_CP024985.1|WP_030232252.1|4083884_4084763_-|phosphatidylinositol-specific-phospholipase-C
MALHRRAFLTGATAVGAAALTGLGTAAPASARTLGSQDWMAGLADSTPLQRMTIPGTHDSGATKGGLYVACQNTSIAQQLDSGIRFLDVRCRVTGGSFAIHHAAFFQDLMFGDVLVACWNFLAAHPSETVLMRVKQEYSEESDATFRAVFDDYLDHRGWRPLFRIADTLPASLGQARGKVVLLADNGGLPGLRYADGNVFDVQDDYNTEPFAKRGRIENQFRKAVQQPGKLFVNYVSTAAYMPPRWNSDRLNPQVHSFVDGGELAGRTGLGIVPMDFPNTRSGLVESLIRHN
>NZ_CP024985.1|WP_030232250.1|4084824_4085412_-|TetR/AcrR-family-transcriptional-regulator
MGNREDLLAGARRCLEEKGYARTTVRDIASAAQVSMAAIGYHFGSREALLNQALFAAIDEWAAGSGRLAGQGATAEERYADTWDRKSRDFLDMRWLWLANIEAFVHAQSSPELLAVLAEGQRRSRRMVAAQLAGVPEDEVAQEDVRALGSVHLALLSGVMVQALTDEEQAPTGRELVRGLRRMVELLEESVPTDG
>NZ_CP024985.1|WP_030232247.1|4085546_4086326_+|alpha/beta-hydrolase
MRHTLTIDDRTLSYLDFGGPGRPLLALHGGMSEGLAFAGLAEALGDEWRVIAPDQRGHGDSDRAPDYSRAGYVADAVALLDHLGLDAPVALLGYSLGGLNAVHLAAAHPDRISALVDIDGAVEVHPAGGAWMDFLKGMRYSAPTREELLAAAGPIGSQFVAQALRPLPEGGWRLPFHPQDMLDSVEACRGDHWDAWLGSTCPAVLVHGVRSTSLPQAQADAMVSRRPGTSYTPLEGDHFVPFTDPAGVHGAVAKFLATL
>NZ_CP024985.1|WP_051841082.1|4086420_4088235_-|bifunctional-metallophosphatase/5'-nucleotidase
MSAKPQRHRTARRLTLSALALTAGAGAMVAAALPAGAASGGGAAPGRTVDVQMLSFNDFHGTLEPPQGSSGTVTERQADGTTKAIPAGGAEYLATALRDARKGHDYSVTAAAGDMIGGSPMLSGLFHDEPTVEALNKMKLDVTSVGNHEFDEGKTELRRMAYGGCHPVDGCFEYGKEYTGAQFQYLAANVTDEKTKRPLMSPTFIWKKGDVKIGFIGVTLEGTPDVVTADGVKGLKFGDEVETINKYAAELNKQGVKSIVALIHEGGLPASGAYNYDCDVPGAGAGISGAIVDIAKNVDPKVDALVTGHTHQAYSCNIPDPAGNPRTVTSAASYGRLFTDTTLTYDRQTKDIVRTPVKSPKPVNKVVTRDLPKAPDMTELITRWNALAAPVASRPMGYISADIAGRGSEAPEKPLGDLIADAQLDATSPADRGGAQLAIMNPGGIRADLAYKAAGAEGDGVVTYGESYTVQPFNNLMNVVDLTGAQLITALQQQVSGTVNGPNPKILQVSKGFTYTLDMTKSGADRIVVDSVRLNGAAIDPAKTYRVAMNEFLAGGGDGFTVLKEHKNKLVGIPDLEAFNNLLGKSSAAAPIAPPAADRITVVK

Crispr_ID: NZ_CP024985_18

• CRISPR_ID: NZ_CP024985_18
• CRISPR_location: 4159777-4159892
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_18

Consensus_repeat	Method
CCCGAGCCGCCCGACCCGGACCCGGA	CRISPRCasFinder

spacers of NZ_CP024985_18

>18.1|4159803|64|NZ_CP024985|CRISPRCasFinder
ACCTCCGGATCCCGAGCCGCCCGACCCGGACCCGGACCCCGATCCGGAGCCAGAACCACCGGAA

CRISPR arrays and Neighbor proteins around NZ_CP024985_18

CRISPR arrays

The CRISPR arrays of NZ_CP024985_18

>merge|NZ_CP024985|18|4159777-4159892|CRISPRCasFinder
CCGGAGCCACCCGAACCGGAACCAGAACCTCCGGATCCCGAGCCGCCCGACCCGGACCCGGACCCCGATCCGGAGCCAGAACCACCGGAACCCGAGCCGCCCGAGCCGGACCCGGA

>NZ_CP024985|18|19|4159777-4159892|CRISPRCasFinder
CCGGAGCCACCCGAACCGGAACCAGA	ACCTCCGGATCCCGAGCCGCCCGACCCGGACCCGGACCCCGATCCGGAGCCAGAACCACCGGAA
CCCGAGCCGCCCGAGCCGGACCCGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030225635.1|4150541_4151357_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl|CDD|234649
NZ_CP024985.1|WP_037686180.1|4169648_4170461_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740452.1|4163640_4164066_-|hypothetical-protein	unknown	unknown	gnl|CDD|236851
NZ_CP024985.1|WP_030225624.1|4160361_4160736_-|CrcB-family-protein	unknown	unknown	gnl|CDD|223317
NZ_CP024985.1|WP_106979751.1|4148019_4150497_+|asparagine-synthase	unknown	unknown	gnl|CDD|223444
NZ_CP024985.1|WP_100660908.1|4141161_4144467_-|AfsR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226418
NZ_CP024985.1|WP_030225642.1|4144631_4145864_-|L-2-hydroxyglutarate-oxidase	unknown	unknown	gnl|CDD|183292
NZ_CP024985.1|WP_030225615.1|4162837_4163587_-|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239321
NZ_CP024985.1|WP_030225641.1|4145883_4147584_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NZ_CP024985.1|WP_037686281.1|4152784_4153345_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660909.1|4156812_4159374_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NZ_CP024985.1|WP_030225629.1|4153423_4154521_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_CP024985.1|WP_078950107.1|4161241_4161583_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240572
NZ_CP024985.1|WP_003949541.1|4168862_4169069_-|developmental-transcriptional-regulator-BldC	unknown	unknown	gnl|CDD|133390
NZ_CP024985.1|WP_078950096.1|4160732_4161245_-|CrcB-family-protein	unknown	unknown	gnl|CDD|376809
NZ_CP024985.1|WP_030225613.1|4164177_4168116_+|ATP-dependent-RNA-helicase-HrpA	unknown	unknown	gnl|CDD|182986
NZ_CP024985.1|WP_078950100.1|4151401_4152781_+|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|379143
NZ_CP024985.1|WP_030225627.1|4154828_4156013_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP024985.1|WP_030225618.1|4162016_4162841_-|cytochrome-c-biogenesis-protein-CcdA	unknown	unknown	gnl|CDD|223856
NZ_CP024985.1|WP_030225603.1|4170708_4171818_+|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl|CDD|223411

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030225635.1|4150541_4151357_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl|CDD|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	2.53018e-86
NZ_CP024985.1|WP_030225603.1|4170708_4171818_+|Glu/Leu/Phe/Val-dehydrogenase	gnl|CDD|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	1.47979e-90
NZ_CP024985.1|WP_030225624.1|4160361_4160736_-|CrcB-family-protein	gnl|CDD|223317	COG0239, CrcB, Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning].	1.79641e-26
NZ_CP024985.1|WP_106979751.1|4148019_4150497_+|asparagine-synthase	gnl|CDD|223444	COG0367, AsnB, Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism].	4.32449e-09
NZ_CP024985.1|WP_100660908.1|4141161_4144467_-|AfsR-family-transcriptional-regulator	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	1.12813e-51
NZ_CP024985.1|WP_030225642.1|4144631_4145864_-|L-2-hydroxyglutarate-oxidase	gnl|CDD|183292	PRK11728, PRK11728, L-2-hydroxyglutarate oxidase.	0
NZ_CP024985.1|WP_030225615.1|4162837_4163587_-|thioredoxin-domain-containing-protein	gnl|CDD|239321	cd03023, DsbA_Com1_like, DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC motif, assumed to be imbedded in a DsbA-like structure. Its homology to DsbA suggests that the protein is a protein disulfide oxidoreductase. The role of such a protein in pathogenesis is unknown.	5.08523e-29
NZ_CP024985.1|WP_030225641.1|4145883_4147584_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	1.5453e-08
NZ_CP024985.1|WP_158740452.1|4163640_4164066_-|hypothetical-protein	gnl|CDD|236851	PRK11114, PRK11114, cellulose biosynthesis cyclic di-GMP-binding regulatory protein BcsB.	0.00094635
NZ_CP024985.1|WP_100660909.1|4156812_4159374_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	3.39922e-120
NZ_CP024985.1|WP_030225629.1|4153423_4154521_-|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	6.58454e-36
NZ_CP024985.1|WP_078950107.1|4161241_4161583_-|metallopeptidase-family-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	3.40686e-47
NZ_CP024985.1|WP_003949541.1|4168862_4169069_-|developmental-transcriptional-regulator-BldC	gnl|CDD|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	3.77068e-14
NZ_CP024985.1|WP_078950096.1|4160732_4161245_-|CrcB-family-protein	gnl|CDD|376809	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB). CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.	3.73553e-33
NZ_CP024985.1|WP_030225613.1|4164177_4168116_+|ATP-dependent-RNA-helicase-HrpA	gnl|CDD|182986	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional.	0
NZ_CP024985.1|WP_078950100.1|4151401_4152781_+|PrsW-family-intramembrane-metalloprotease	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	3.15183e-46
NZ_CP024985.1|WP_030225627.1|4154828_4156013_-|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	4.72914e-39
NZ_CP024985.1|WP_030225618.1|4162016_4162841_-|cytochrome-c-biogenesis-protein-CcdA	gnl|CDD|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	8.20268e-23

Protein sequences

>NZ_CP024985.1|WP_100660909.1|4156812_4159374_-|DEAD/DEAH-box-helicase
MSISSSDRSVMPENDTHEIVDAETLAVTEAMEAIEADEIIEALEADVTGDTADSADEAGDAEPTTTFADLGLPEGVVRKLAQNGVTTPFPIQAATIPDALAGKDILGRGRTGSGKTLSFGLPTLARLAGGFTEKKKPRAIILTPTRELAMQVADALQPYGDVLGLKMKVVCGGTSMGNQIYALERGVDVLVATPGRLRDIINRGACSLENVEVAVLDEADQMADLGFLPEVTELLDQIPGGGQRMLFSATMENEIGTLVKRYLSNPVTHEVDSAQGNVSTMTHHVLVVKPKDKAPVTAAIAARKGRTIIFVRTQLGADRIAEQLIEAGVKADALHGGMTQGARTRVLADFKDGYVNALVATDVAARGIHVDGIDLVLNVDPAGDHKDYLHRSGRTARAGKSGVVVSLALPHQRRQIFRLMEDAGVDASRHIVQGVGAFDPEVAEITGARSLTQVQADSANNAAKQAEREVADLTKQLERLTRRAAELREEADRLVARSARERGEDPEAAVAEVVEAAEAEVAAAVAAVAEPVAQERTFERRDDRGNYERRDNRRDDRGDRGGDRGGFRRDDRPSGGFRSGGDRRDDNRGGGFRRDDRPSGGFNRDDRGGDRGGFRRDDRPSGGFRSGGDRRDDNRGGGFRRDDRPSGGFNRDDRGGDRGGFRRDDRPSGGFRSGGDRRDDNRGGGFRRDDRPSGGFNRDDRGGDRGGFRRDDRPSGGFRSGGDRRDDNRGGGFRRDDRPSGGFNRDDRGGDRGGFRRDDRPSGGFRSGGDRRDDNRGGGFRRDDRPSGGFNRDDRGGDRGGFRRDDRPSGGFRSGGAGERPYGRRDDNRPSGSGSTGSFGGRRDDKPRWKRNG
>NZ_CP024985.1|WP_030225627.1|4154828_4156013_-|serine/threonine-protein-phosphatase
MAGLGRQGGDASGTTEPGDGAGRQVLRVLPALLILLGLVFDVLTPPRFTGSPFFSAAPLIAAPVFSFLATAVTGVAASGAVVALHLHNAVDWKADALTELVTVVTVSGLALLINRVVRRSGERLASARGIAEAAQRAVLPTPAERIGGLHVSARYEAAQADAFIGGDLYAVQDTPYGVRLAVGDVRGKGLGAVEAVAVVLGAFREAADTEPTLEALAERLERALAREGVRRDSLDAVEGFTTCVLGEIPAGAGVLRLLNRGHPEPLLLYADGGLAVLEPAEPALPLGLGLGELWPGPRDPVGEWPFPPGSTLLLYTDGVTEARDAAGVFYDPAARLRGRVFPGPGEVLGALSSDVRRHTGGGTTDDMALLAVGRPEEGQPERRRTVPVVRREEE
>NZ_CP024985.1|WP_030225629.1|4153423_4154521_-|M23-family-metallopeptidase
MASNSPSPEGIDVPETPTAGAWGEWNPTEDSARSVRGKHRVLKQRGGLARSSTVLGVGVIAAVGAGGIATAQDRPQVAISMPSLPDLPDLLGGGGHAAGAAGTDTAAPAGAAAAQSAGIPGQADGRGHGQADAGEALRHRILQQAESQQEAVETQARADAERTAREAAAQEARAQKEAADREAETARAAAEKAAAEKAEADKAAEAAATTAAKAAEGAEGGGSGSGAGAGTKASGGYSLPTSSYTLTSHYGDSGSMWSSGHHTGLDFAAPTGTPVKAVGGGKVISAGWSGAYGYRIVLQLDDGTEVWYCHLSSMSVTSGTVGAGETIGRVGATGNVTGAHLHLEVRKGGSTVDPLAWLESKGLSV
>NZ_CP024985.1|WP_037686281.1|4152784_4153345_-|hypothetical-protein
MTRGRTGLIIGGAFGLAFIAVNAGAAAPLTVPMRLLAIAAFVGLFFASRPPAAGAGADATARTEPAAPAARTAFGRRYWLVVAAEAVAALAGLFLTARVFHAPHLAVACIALVVGVHFFALAAVWRQTSLHVLGAAMTACGAAGLLLGVAGAGAAAVSAVAGIAPGVLLLASAWWSALAARPRAAL
>NZ_CP024985.1|WP_078950100.1|4151401_4152781_+|PrsW-family-intramembrane-metalloprotease
MLRALSRVLARTPDPVRVCVPVTLLTATGFTILELVREQTGTAGFLVGLGLALLPVPPLMAAFRWLGRAAPAPWRQLMFCFGWGACTAALIAILANSFATEWIAAATTDPFDADRFGSVAIAPVVEESAKAAALLLVFAFRRRQFTGPADGFVLAGFTATGFACTENVLYLGNAFEEDLAKGTGVLDSVTAATFFVRAVLSPFAHPLFTVLTGLGFGMAAVGAGRVRGAGPPLLGLGLAMGLHALWNGSSHFGEYGFYAVYGCVMVPAFALLLGLAVRIRRHRLRAVAAELSVYARAGWLGPAEVPALASMPARSLARALARRSGGRPAARAVSRYAADAAALALLRRHTRQSAAPDREFAVRERELLDRLWLRRATAGPVLARAAVLEELLPPWYDPLAGPHTPQPPQATREPLATLPSQAFARPPAPTTPAQAPTPTPSATAVPSPRTPALSASVRP
>NZ_CP024985.1|WP_030225635.1|4150541_4151357_+|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSESPNPQPSLPDTAPEATAYVPPKWRTEPRFPDGPAPDPAGSHHERRIRSFQPRRSRVTTGQGEALKRLWGTWGLDIDGHEVIDLKKLFDGLPVVLEIGFGMGEATAQMAAADPSTGILAADVHTPGQGNLLALAERGGMTNVRVANGDAIILLREMLPPDSLAGMRVYFPDPWPKARHHKRRLIQPEFLDLAATRLAPGALLHCATDWEPYAEQMLEVLTAHPEFENTQADGGYAPRPEFRPLTRFEGQGLDKGHVVHDLLFTRARPKN
>NZ_CP024985.1|WP_106979751.1|4148019_4150497_+|asparagine-synthase
MAETDLWGGGNGTPNTEWPGRVRSHARPRSHSRTPVSWQHGPRATRGPAGRALRRRPRRPSRPLPRSCAHGLGEAAVRWLVGWSSIAASFGTAGRVSHQGEPHRGGGRADYADPARGPYGPPGAHPHAAPPRGGIADAAYADDPAAQDAERTVHPVGSQLLWGDPDPLWAVGDWRPDEIRTVTADPADPFTRLAVLGCCGATDAELRRALYAARGGALRHLTEWPGSYTAVVQAGRRITVLGDLAGARPVFYTPWAGGTAYATAALPLADLIEAQLDVGHLAALLACPDSPEALGDGTPYVGVRRIPPGHTLILREGSREITGYEPVASLAVAAPEADPERAVEGVREALTAAVRARLTAPRHAPDALVTDPGPVPGMGPADRRAARGAPAPGVGADLSGGSASATLALLAAGLPGAPGTLPGTGSRLLAVTFNDLATPQGREAELERAHALAADPRLHHVVVAAAAEALPYAELDGPLTDEPGPSLVSAARERRRLAAGSADHFTGHGARQVLDAHPARMADLLMDRRRRHLLRPVAALARAASASGESLLVPLTVYSAARRLARTPYRAGIEAAAARLREGGVAAAVSGPVDASLAALTWSRPGPAAGWLTGEALAEVSIRLRAAAGRPPLSLRPGEARARALLARHAADHRVFEQAVEVRSQRLHAPFLDNQVVRAARALPESLRVQPGARAEILRRVLASAGVRELPPGWGATAHAPNETATRLGLRAALPGLLSLFSAPLLADAGLVEARVVQRALSDAADGRPVPLDGLAELVSMELWLRRLLARRGTCWTGTSTPRRRAVPALDASLPRLTRGAPAAR
>NZ_CP024985.1|WP_030225641.1|4145883_4147584_-|hypothetical-protein
MSRELREPNEKLGAVLALAGISNAGLARRVNDLGAQRGLTLRYDKTSVARWVSKGMVPQGAAPHLIAAAIGAKLGRPVPLHEIGLADADPAPEVGLAFPRDIGAAVRSATDLYRLDLAGRRGGGGIWQSLAGSFAVSAYATPASRWLICPADSSVAREPGPVREKTPLPVPVPAAPAPAAGEASGATGGAGGAGGAARAVAPRQASAATGRSAQTPAQGVVPAGPGPETGRQTPAAAPAPATAPAPPAPPVPAAVLPDASPQRVGHSDVTKLREAAEDARRWDSKYGGGDWRSSMVPECLRVDAAPLLLGSYSDEVGRALFGATAELTRLAGWMAFDTGQQEAAQRYYIQALRLARAAADVPLGGYVLASMSLQATYRDFPDEGVDLAQAAVERNRGLATARTMSFFRLVEARAHAKAGDSAAAGAALRAAEGWLERSRDGDPDPTWLGFYSYDRFAADAAECYRDLKLPRQVRRFTEQALSRPTEEYVRSHGLRLVVSAVAELESGNLDAACAAGTRAVEVAGRISSARTNEYVRDLLHRLEPYGDEPRVAELRERARPLLVTPA
>NZ_CP024985.1|WP_030225642.1|4144631_4145864_-|L-2-hydroxyglutarate-oxidase
MQYAGVGGVSVGGGVDCDVLVIGGGIVGLSTAHALSRLAPGTRVAVLEKEAGPARHQTGRNSGVIHSGIYYRPGSLKARFAVRGAAEMVKFCAEHGIAHEVTGKLIVATERAELPRLHSLVQRGRENGIPVRELGPAQIAEYEPEISGLAAIHVGTTGIVDYGQVAAQLAESSGAEIVYGAEVDLISRRSSAVAVRTTSGLVVRAKVLVNCAGLQCDRIARLAGDDPGMRIIPFRGEYHDLARPELVRGLVYPVPDPAFPFLGVHLTRGIGGGVHVGPNAVPALAREGYDWATVRPRDLATELAWPGSWRMASRHWRYGAGEIHRSLSKRAFTDAVRRLLPGVTAADLTPAGSGVRAQAVLRDGTLVDDFLIREAPRTIHVLNAPSPAATASLPIGHEIATRTLTTLHTS
>NZ_CP024985.1|WP_100660908.1|4141161_4144467_-|AfsR-family-transcriptional-regulator
MRYLILGVTEARDETGAPLPLGGARLRALLAALALRAGGPAATPVADLVDEVWGDDPPRDAPAALQALVSRLRRALGSRDSVRADPAGGYRLAAAREDVDLHRFTRLAALGTEQLAAPAADPAAAAATLREALSLWRGPALADLPEPARTSHAAPAEARRTRAARDRVEADLRSGATAPAALLPEIEALIHEHPYDEDLRAQQLRALRAAGRSADALAAYERTRRDLAEGLGTDPGPRLRALHAELLQAPAPAPPVPPQPRGNLRPRLTSFVGREPELAALADDLARSRLVTLTGPGGSGKTRLAEHAAAGRPGSGWLVELARLDHPAAVPGAVLSALGLRESSLVAREKTTTADPADLLVEHCAHRSLLLVLDNCEHVIGAAAELAERLLTHCPGVRILATSREPLGVPGEFLRPVEPLPPPTAHRLFADRAASARPGFTPADDPAAVAEICARLDGLPLAIELAAARLRLLTPRQIADRLDDRFRLLTGGARTLLPRQQTLRAVVDWSWDLLDASERAVLARLSVFAGGCDLAAAEAVCADTADTADTADTADTAGTAGTVGTLDVADVLGSLVDKSLVLAEPDGDESTPGMRYRMLETIHEYAAERAAADPAALDAAARRHAAHYLAFAERAEPLMRSRAQLPWIRRVETELDNLRTALDTTLGTPTPDATESAQRIALALGWFWWLRDYRVEGVEWIGRILDRTPADGPEGSRAYWNALHLRILHMFLLAESNRGDHFRTPEYRALAGRIQDIFRQDSPESVRFPGMLWPALGFLTGETADFLADLDRGVANARRHAGDWELGVILMFRAHTAIDTTGGLPTVDADLAELHRIASRVGDRWSRAQVASAAGEMALSRGRYDEARAEYEECLRLAREVGAHTEVPFALARIAEAVYSGGDLDGAERLLAEAEREADRQGGLYDVVAFARLLTAFFALRRGDTARARTACEEARAAADGITGPAQFAAGLATVEAALLRREQGPEAGLAKAAQGLADAVAARCAERFLAALAETAALLLADAGRPAESVRVLAAATAWRAGHPRSVPEEAVLEDLPARTRALLGAAAQAEAEAEGRTLTPAEVAALLAAPAAPAALSGS
>NZ_CP024985.1|WP_030225624.1|4160361_4160736_-|CrcB-family-protein
MNWLLVVAGAVVGAPLRYLTDRAVQSRHDSVFPWGTFVVNAAACLLLGGLTGAVLAGAGSSGAVPLLGTGLCGALSTYSTFSYETLRLAERGWKFLAVANVLGSVLVGLGAVHLGSQVARQLFA
>NZ_CP024985.1|WP_078950096.1|4160732_4161245_-|CrcB-family-protein
MTRPVPGGEAIDPDVDLHVPAQRAEPQGRVLAAIAAGGALGASARFGVGLLWPAGPGAFPWATFWINVSGCALIGVLMVLISEGGRSAPHPLVRPFLGVGVLGGFTTFSTYAVEFSGLLDAGRAQVALAYAGLTVAAALGAVWAAASVTRLVAGSAVRPAPGRPGGRGRG
>NZ_CP024985.1|WP_078950107.1|4161241_4161583_-|metallopeptidase-family-protein
MTREEFEELVAEALDRIPPELTRLMDNVAVFVEDEPPADDPELLGLYEGTPLTERGEWYAGVLPDRITIYRNPTLRMCEDRESVVAETEVTVVHEIAHHFGIDDERLHALGYG
>NZ_CP024985.1|WP_030225618.1|4162016_4162841_-|cytochrome-c-biogenesis-protein-CcdA
MNGIGYLAALLGGLLALLSPCSALLLPAFFAYSIDSASRLLARTGIFYAGLASTLVPLGAAGSYAGRFFHGHREGLVLFGGWLIIALGLAQILGLGFSSRRISEMSGRIRPVTALSVYALGAVYGLAGFCAGPILGSVLTVAAVSGSPVYGGLLLAVYALGMAVPLFLLALLWERFDLGRRRWLRGRPLRLGPLRLHSTSLLSGLFFITLGALFLAYDGASALPGLLDVDDSYAVEERVRSVAEAVPDWALLGLVAAGAVAVGLVRWRRTQREG
>NZ_CP024985.1|WP_030225615.1|4162837_4163587_-|thioredoxin-domain-containing-protein
MSSSTRKPAPRKRASRTPLLVCAGVAVAAITLGLVSWQASSSRDGSRDTTASAAGSTPRAEDPLAELKALARREAGDKLALGRPDAPVVLVEYSDFKCGYCGKFARDTEPALVKKYVDAGTLRIEWRNFPIFGADSEAAAKAAWAAGQQDRFAAFHAAAYADGAKEKGFGEERLVELAREAGVPDLERFRRDTAGPQAAEALRRDQEEGYRIGVSSTPSFLVGGQPLAGAQPLAAFEAAISRAAAAAGK
>NZ_CP024985.1|WP_158740452.1|4163640_4164066_-|hypothetical-protein
MSRRRRVWCLLAAVLTTLLATVAPTASAAPTQVTSTHATPTHATPTHATPAHATPAQAAPAFGSVVMAGVQEQGPRCAPDGPERGGVPVVPPRSGCEHAQLPAGGVVPGEVRPRGTAPLRVLVRGPDRTPPGPVELSVLRV
>NZ_CP024985.1|WP_030225613.1|4164177_4168116_+|ATP-dependent-RNA-helicase-HrpA
MSTSFAALQTLLGEISLRDAHRLGRRLEGARRIRKPEAKQAVLDEIAAEAEKAAARLAGRASRMPEVTYPENLPVSQKKDEIAEAIRDHQVVIVAGETGSGKTTQIPKICMELGRGVRGMIGHTQPRRIAARTVAERIAEELKSEIGQTVGWKVRFTDQVDQDATFVKLMTDGILLAEIQTDRELRAYDTIIIDEAHERSLNIDFLLGYLATLLPKRPDLKVVITSATIDPERFSRHFGDAPIVEVSGRTYPVEVRYRPLLEEDSEDADRDQITAICEAVEELQAEGPGDILVFLSGEREIRDTADALEKRKLRFTEVLPLYARLSHAEQHRVFQQHTGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSHRTKVQRLPIERISQASANQRKGRCGRTSDGICIRLYSEDDFDARPEFTDAEILRTNLASVILQMTAAGLGEIEKFPFIDPPDHRNIRDGVQLLQELGALEQGEKSAQEGRKGQRLTPMGRQLSQLPVDPRLARMVVEADKNNCVREVMVIAAALSIQDPRERPSDKQTQADQNHARFKDETSDFLSFLNMWRYVREQQKERGSSSFRRMCKQEYLNFLRIREWQDIYSQLRTVAKTMGIHVNEADAPETNIHISLLAGLLSHIGLKDTDKNEYLGARSAKFAIFPGSSLFKKQPKFLMSAELVETSRLWARVNAKVEPEWVEPLAQHLIKRTYSEPHWEKDQAAVMAYEKVTLYGVPIVAQRKINYGRIDPEVSRELFIRNALVEGDWRTHHKFYADNRKLLTEVEELENRARRRDIVVDDETLFDFYDQRIPEHVVSGAHFDSWWKHKKREEPELLDFEREMLLTEKAAGVTKADYPDSWQQGRLKFRVTYQFEPGADADGVTVHIPLQVLNQVTDEGFDWQIPGLREEVVTELIRSLPKPIRRHYVPAPNFATRFLDTAVPLQEPLHVTLARELHRMVGVPVSADDFDLTRIPDHLKITFRIIDERRKKLAEDKDLEALRLSLKPKARQALSKAAAATAERAGGESLERSGLTDWTIGTLTRVFETRRAGQPVKAYPALVDAGTSVCVRLFDTEAEQQQAMWLGTRRLILLNIPVNPAKFASDKLTNQQKLALSRNPHGSIQALFDDCATAAADKLIADHGGPAWDEAGFRKLYDAVRADLVDTTVRTVAQVQQVLAAWQACERRLKATNSLALMANVADVKAQLAALVPAGFVTLAGLRRLPDLMRYLVAADRRLQQMPTGAQRDTTRMEKVHEMRDEYLWLLEQLPKGRPVPEAVTEIRWMIEELRVSYFAHALGTAYPISDKRIVKAVDALAP
>NZ_CP024985.1|WP_003949541.1|4168862_4169069_-|developmental-transcriptional-regulator-BldC
MTARTPDAEPLLTPAEVATMFRVDPKTVTRWAKAGKLTSIRTLGGHRRYREAEVRALLAGIPQQRSEA
>NZ_CP024985.1|WP_037686180.1|4169648_4170461_-|hypothetical-protein
MPVVPYASYLRVYEPLAAFPEPERTHWADYARRGTAPTAQDELRRSLSDLVRVPVVGVPAHESADAFTTELDGSLLVCPWRTRLRGWLALRELAESFPPPVLDAVLPAGTRRRAAEEYEAWRERNPDARPWIRTGVWQVPLRWFVLVADEEREYVPGERLRYRTPMVQARRRLARGLRTLRQAEGYGPLAEGLVEVGSWLEEFHPRSMVELDYGGLLHALPADALAGDRSARDLAEGIAALRAGDLDGASQVYGELALRWRKVRERLFAN
>NZ_CP024985.1|WP_030225603.1|4170708_4171818_+|Glu/Leu/Phe/Val-dehydrogenase
MTEMTDGVLHTLFRSEQGGHEQVVLCQDRASGLKAVIAIHSTALGPALGGTRFHAYASDEEAVRDALNLSRGMSYKNALAGLDLGGGKAVIIGDPSALKSEELLLAYGRFVESLGGRYVTACDVGTYVADMDVVARETRWATGRSPENGGAGDSSVLTAFGVFQGMRASAQHLWGDPTLRGRKVGVAGVGKVGRHLVEHLLADGAEVVITDVREESVREILDKHPGGEVTAVVDTEALIRTEGLDIYAPCALGGALNDDSVPVLTATVVCGAANNQLAHPGVEKDLADRGILYAPDYVVNAGGVIQVADELHGFDFDRCKAKAAKIFDTTLAIFARAKADGIPPAAAADRIAEQRMADALAARTAARTA

Crispr_ID: NZ_CP024985_19

• CRISPR_ID: NZ_CP024985_19
• CRISPR_location: 4616415-4616530
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_19

Consensus_repeat	Method
CCCCGCGCCTCAAACGCCGGCGGGGCTGGA	CRISPRCasFinder

spacers of NZ_CP024985_19

>19.1|4616445|56|NZ_CP024985|CRISPRCasFinder
TTTTGGCGCGCCGGGAGGGGGTGCGGCTCAAGGATGCAGGGGCTCCGCCCCCGGAC

CRISPR arrays and Neighbor proteins around NZ_CP024985_19

CRISPR arrays

The CRISPR arrays of NZ_CP024985_19

>merge|NZ_CP024985|19|4616415-4616530|CRISPRCasFinder
CCCCGCGCCTCAAACGCCGGCGGGGCTGGATTTTGGCGCGCCGGGAGGGGGTGCGGCTCAAGGATGCAGGGGCTCCGCCCCCGGACCCCCGCGCCTCAAGCGCCGGCGGGGCTGGA

>NZ_CP024985|19|20|4616415-4616530|CRISPRCasFinder
CCCCGCGCCTCAAACGCCGGCGGGGCTGGA	TTTTGGCGCGCCGGGAGGGGGTGCGGCTCAAGGATGCAGGGGCTCCGCCCCCGGAC
CCCCGCGCCTCAAGCGCCGGCGGGGCTGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030228635.1|4606547_4607207_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP024985.1|WP_030228588.1|4623578_4624853_+|aspartate-kinase	unknown	unknown	gnl|CDD|235843
NZ_CP024985.1|WP_030228603.1|4619343_4620015_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP024985.1|WP_051840639.1|4610600_4611863_-|acyltransferase	unknown	unknown	gnl|CDD|376607
NZ_CP024985.1|WP_030228590.1|4622820_4623468_+|DUF5063-domain-containing-protein	unknown	unknown	gnl|CDD|374737
NZ_CP024985.1|WP_037686867.1|4620821_4621538_-|SLATT-domain-containing-protein	unknown	unknown	gnl|CDD|375613
NZ_CP024985.1|WP_030228632.1|4607203_4608532_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP024985.1|WP_063760270.1|4611801_4612821_-|hypothetical-protein	unknown	unknown	gnl|CDD|283837
NZ_CP024985.1|WP_078950246.1|4609288_4610491_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_CP024985.1|WP_030228586.1|4624849_4625923_+|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
NZ_CP024985.1|WP_037686869.1|4614697_4616272_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP024985.1|WP_030228605.1|4617858_4619211_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|235687
NZ_CP024985.1|WP_030228616.1|4613579_4614203_-|LysE-family-translocator	unknown	unknown	gnl|CDD|224199
NZ_CP024985.1|WP_030228614.1|4614208_4614616_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP024985.1|WP_030228618.1|4613055_4613535_+|diadenosine-tetraphosphate-hydrolase	unknown	unknown	unknown
NZ_CP024985.1|WP_030228593.1|4622228_4622828_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NZ_CP024985.1|WP_030228600.1|4620136_4620787_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_078950239.1|4621823_4622168_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
NZ_CP024985.1|WP_030228607.1|4617029_4617677_-|thiamine-biosynthesis-protein-ThiJ	unknown	unknown	gnl|CDD|153234
NZ_CP024985.1|WP_030228629.1|4608620_4609292_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030228635.1|4606547_4607207_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.54898e-74
NZ_CP024985.1|WP_030228588.1|4623578_4624853_+|aspartate-kinase	gnl|CDD|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NZ_CP024985.1|WP_030228603.1|4619343_4620015_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.28614e-26
NZ_CP024985.1|WP_051840639.1|4610600_4611863_-|acyltransferase	gnl|CDD|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	2.93082e-16
NZ_CP024985.1|WP_030228590.1|4622820_4623468_+|DUF5063-domain-containing-protein	gnl|CDD|374737	pfam16702, DUF5063, Domain of unknown function (DUF5063).	6.96882e-48
NZ_CP024985.1|WP_037686867.1|4620821_4621538_-|SLATT-domain-containing-protein	gnl|CDD|375613	pfam18183, SLATT_2, SMODS and SLOG-associating 2TM effector domain 2. The SLATT domain contains two transmembrane helices. SLATT domains are generally predicted to function as pore-forming effectors in a class of conflict systems which are reliant on the production of second messenger nucleotide or nucleotide derivatives. SLATT domains are predicted to initiate cell suicide responses upon their activation. This SLATT family is the only prokaryotic SLATT family to exist as a standalone domain, with no as-yet discernable genome associations.	3.80364e-122
NZ_CP024985.1|WP_030228632.1|4607203_4608532_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.4566e-34
NZ_CP024985.1|WP_063760270.1|4611801_4612821_-|hypothetical-protein	gnl|CDD|283837	pfam06259, Abhydrolase_8, Alpha/beta hydrolase. Members of this family are predicted to have an alpha/beta hydrolase fold. They contain a predicted Ser-His-Asp catalytic triad, in which the serine is likely to act as a nucleophile.	9.90625e-36
NZ_CP024985.1|WP_078950246.1|4609288_4610491_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	7.99674e-41
NZ_CP024985.1|WP_037686869.1|4614697_4616272_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.21553e-82
NZ_CP024985.1|WP_030228605.1|4617858_4619211_+|aspartate-aminotransferase-family-protein	gnl|CDD|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
NZ_CP024985.1|WP_030228616.1|4613579_4614203_-|LysE-family-translocator	gnl|CDD|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	6.57252e-39
NZ_CP024985.1|WP_030228614.1|4614208_4614616_-|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.18307e-11
NZ_CP024985.1|WP_030228593.1|4622228_4622828_+|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	2.69569e-123
NZ_CP024985.1|WP_030228586.1|4624849_4625923_+|aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	1.22207e-126
NZ_CP024985.1|WP_078950239.1|4621823_4622168_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	1.02997e-36
NZ_CP024985.1|WP_030228607.1|4617029_4617677_-|thiamine-biosynthesis-protein-ThiJ	gnl|CDD|153234	cd03140, GATase1_PfpI_3, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	1.04985e-60
NZ_CP024985.1|WP_030228629.1|4608620_4609292_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.91977e-74

Protein sequences

>NZ_CP024985.1|WP_037686869.1|4614697_4616272_-|serine/threonine-protein-kinase
MEPLHPADPQHVGPYRVLSRLGSGGMGQVYLARSDRGRTVAVKLVHPGLALREEFRARFRQEVAAARRVGGAWTAPVLDADTEAEVPWFATGYVAGPSLRQTVAHDFGPLPTRTVRILAAGLAYALQDIHRAGLIHRDLKPSNVLLTLDGPRVIDFGIARPLDTPDSGLTRPGELVGSPGFMAPEQVRGEAVTPACDVFCLGAVLAYAATGRQPFGDAEQPGGAAGLLLRIVEAEPELDGVPAELRELVADCLRKDPAARPDPAAVLDRVGAGWTVADGRALEPWLPAPLVDRLGRHAVQLLDREDPGPRHTLPPAPTAVAPPPPPLPPAPPASYPYGPPPAVPAPRPPVASTAFLVAVAVVVAAAAGGTVYAVMSSTPEPLPPGPAVTASAPSAPTGAGPTDPKAPGTGTSSGGGPAARLPQSYVGTWRAASGSATWRLDLTPGAVGEPVMTLRVDDPGYSCSWRATLRGAPDPVELDASTVTSGPAPTCTPGGWSRLRLLPDGTLRRELDGGSNPPLTYHRE
>NZ_CP024985.1|WP_030228614.1|4614208_4614616_-|nuclear-transport-factor-2-family-protein
MEPLKVVAHLWERIEARDWDGVAALVAEDAVIEWPVSGERIVGRANFVAVLRDEGEESEDDERPLGAVEVLRILADGDLVVTEVEIPEEHVVYRAVSLWTVRDGEIVGAREYWTSPGQDPAPRWRAVYVEPLVAD
>NZ_CP024985.1|WP_030228616.1|4613579_4614203_-|LysE-family-translocator
MLTQLAAATGVLALLTLVPGPDMAIVTRRAVSRGRADGLRTVGGIAAGLLLWGALTVAGLAALLAASAEVYLVVKLAGAAYLCFLGVQSLRRPGGGPEGDPDGAGSDGGSGSAWRTGLVSNALNPKIAVFYTGLLPTLAPQGLRPAAGMALLVLVHVLLTLLWLSAYVYVLSHARRFFTRPRVRRAMDRVTGVVLIGFGVRVATSAA
>NZ_CP024985.1|WP_030228618.1|4613055_4613535_+|diadenosine-tetraphosphate-hydrolase
MNENDWKQDRIGSAHRGENPTVLRRLDSGFAAIGDRQFLPGYSVLLTDDPAVTRLSELSRSRRIAYLTDLERLAEAVERACARLDPAFRRVNIEILGNTDPYLHAHIWPRYDWEPADLVRMPVWLYEDEECWRGERHALAPRHDGLRTAIAEELEALLG
>NZ_CP024985.1|WP_063760270.1|4611801_4612821_-|hypothetical-protein
MTMGSRIRRTLLAGLVATAVVVPVSAAASPKVPAPAPAAFAASATAQSRYAANLAVMGEASRMAGDAGRTGRAEKLRTMAAAAPGQAGGAQFLTFDGRGKGRAIEVLGDLGTADRIAVLVPGSDTTLDTYQRFRDGARSLQQRLQREHPRSAVIAWLGYDTPGTVSTTVLTAARAEEAAAELGPFLDRLGEMTGADARISLLCHSYGSVVCARTRTGPRVSDVVLYGSPGTGIPSAGRMPTGARVWAGRGSEDWISGVPHVRFAGLGFGTDPVDPAFGARRFAAGSAGHSDYLRPGTESLESLARIVIGATGSGSGSGSDDLTGPGPAVPSVRREASHA
>NZ_CP024985.1|WP_051840639.1|4610600_4611863_-|acyltransferase
MTSPAPAPPSPPSAGRPRMRELRTRWSALADRVDSATPAHRDRSVDALRAFAILGVVLGHWLVTALTVTDGSLHGASPLAAMPWLAPVSWVFQTLAVFFLVGGHVADQGHAAARARGVSYGAWVGQRLGRLFRPVAAVLTLWAVVAGGLLVGGAEPETVRTLLKLVWSPLWFLLVFAALTAATPLVARISPLWPLAVVAGVDVWRFGLGGPEWIGWVNVAAGWLVPFTLGAAWSRGAFSRRRQSLFLLAGGAAATAALILWGGYPASMVGVPGAAVSNLNPPTLAAVAFGLAQCGLALLVRGPLARVMERPRTWAKVALLNLSAMTVFLWHQTAMMSVTAVGLLFSTELPGLHTAPGSAGWIVARLLWLPVFAAALTVCWSAFRVHEQPRAARTPRTAVISAAPRVRVPGTARLEEVGRV
>NZ_CP024985.1|WP_078950246.1|4609288_4610491_-|sensor-histidine-kinase
MSRPRWLARLPHAVVLYLAVLFCFLTNEQLSHYHVTGGPSLVLALMSGVPVAVALSRPIAAWWLGLLAAGLIAWTIHSEVGQGQSWPWMPAGFFALAPLILLAALRVPPRTTVAVVTVPVGLSAAAELLAKPEHSTTSFFTSSLVFGIVGLLGYSLRAVRLARGQLVVQETLTEEERARRTLLEERSRIARELHDVVAHHMSVISIQAQVAPHLVENPSEELKENLAGIRENALEALTELRRVLGVLRSEQPGDPAAPQHPQPTLAELDGLVDNVRGAGLDVVTEVAGIRRPLAPGVELTAYRIVQEALSNCLRHAPGSRVEVGIAYGPRELHLCVSNSAPSRAAPPSVGAGHGLLGMRERAGMLGGELAAGPRPGGGYEVSAVLPMDPPGGSSETKKDA
>NZ_CP024985.1|WP_030228629.1|4608620_4609292_-|response-regulator-transcription-factor
MSTPIKVMIADDQMMVRQGFTVLLNAQPDIEVVGQAVDGADAVAKVAELGPDVVLMDIRMPGMGGIEATSIITGVPESTVKVLVLTTFDLDEYVYEALRAGASGFLLKDASADQLAEAVRVVAAGEALLSPNITKRLITEFSRMGAPRAPSRARIDELTERETEVLSLIAQGLSNAEIAGHLTVAEQTVKTHVSRILVKLGLRDRTQAAVFAYETGLVRPAGY
>NZ_CP024985.1|WP_030228632.1|4607203_4608532_-|two-component-sensor-histidine-kinase
MTQTTTGATPRPPELRLASGLMQSLRDDMLTDAFAYRPLAPMRTDGPIVRRLPERIRYRAAYLPHAAVVVTAFFVVLLASTTGTVGMSPAPLTLAGLVAAAPVLMTLVRPMGAFWAALAATVVLSVLQDRIFTWPWSPGTFVAYLAVMVFVGLRTKPRVSGWMWVITVLFGTALQILFGADRAGSIAPMAFASAVGLLLVTVRNTRREARQEVTAVLEVTAFERDRRTLLEERTTIARELHDVVAHHMSVVAIQAEAAPYRVKNPPPELEAAFVTIRENAVAALTELRRVLGVVRSADYEAPDTPQPTLASLDGLLTNVREAGLSVEKTVTGAVRELPQGVELSAYRIIQEALSNSLRHAPGSAAEVEVSYVLGGLGIRVVNGPAVGDVPPSPGAGHGITGMRERVAMLEGEMTAGESPSGGYEVAVFIPVRSRPQPEEDPA
>NZ_CP024985.1|WP_030228635.1|4606547_4607207_-|response-regulator-transcription-factor
MTIRVLIVDDQMMVREGFSVLLNAMEGIEVVGEAVDGRQAIAQVAALRPDVVLMDIRMPEMNGLEATRQIVAADADAKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLAEGVRVVAAGEALLAPSVTKRLIVEFSKLAQTPRTVDPVGVAELTERETEVLVLIAQGLSNGEIADRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYETRLVTPA
>NZ_CP024985.1|WP_030228607.1|4617029_4617677_-|thiamine-biosynthesis-protein-ThiJ
MSGTPSGPRHEPKPVHLAVYDTYADWETGHTTAHLTQRGHTIRTVGLVAGRTVTTMGGLRIQPDLALADLRPEDSSLLILTGASLWDTGDELAPFAAKARAFLAAGVPVAAICGATAGLAREGLLDGRAHTGAVSFYLAQQPGYGGAAHYVEADAVTDGDLITAGPTEPAAFAREVFARLGVYRPEVLDAWYRLFHDSDASAYPVLMAAAEAGDA
>NZ_CP024985.1|WP_030228605.1|4617858_4619211_+|aspartate-aminotransferase-family-protein
MTPHVTGAAVKAADRAHVFHSWSAQALIDPLAVAGAEGSYFWDYDGNRFLDFSSQLVNTNIGHQHPKVVAAIQEQAARLCTLAPGFAVDVRSEAARLIAERTPGDLDKIFFTNGGAEAVENAVRMARLHTGRQKVLSTYRSYHGATAAAINLTGDPRRWPSDTAAAGVVHFWGPFLYRSPFHATTEAEECERALAHLADTIAFEGPATIAAIILESVPGTAGIMTPPAGYLAGVRELCDRHGIVFILDEVMSGFGRTGKWFAAEHWDVTPDLITFAKGVNSGYVPLGGVAISAAIAETFATRPYPGGLTYSGHPLACAAAVATINAMEEEGIVDNAARIGAEVIAPGLAAIAERHPSVGEVRGLGTFWALELVRDKETREPLVPYNAAGAANAPMAEFAAACKASGLWPFVNMNRTHVVPPCTVTETEAKEGLALLDEALSVADRHTAGA
>NZ_CP024985.1|WP_030228603.1|4619343_4620015_+|GntR-family-transcriptional-regulator
MPGSGSGAVTRNTLRQQIADALRDEVLAGRLPPGTEFTVKQIAEQYEVSATPVREALVDLSAQGLLESVQHRGFRVRTYTVDDFRGMIEARTLILDGIFRCLVERGVAPGAAEMLVSVRRRGEEAQRAARSGSLEVLIGYDLRFWRELSGLVGNPYISEFLHRIRIQCWVFSVPHLQGSPELRTALWDGHNELVDAVTLADADEVRRLVRAYNQHGLDWAARL
>NZ_CP024985.1|WP_030228600.1|4620136_4620787_+|hypothetical-protein
MACDLWLVPLVDVLCHSPDNPFAEEIASYDKALGEAGLPSVPVFAYMPGLSGDVAPVAGFDYDALHFLRRAYLLQICGLPVTPVDELGGDYEQLLEMFESTAQQSHLVWHYDHAGAYVPVDFPAPLANEELLAGGGPLGSAQGLLRELAFVAPAIGIDPGNPPAAPAPPGGPTSLEEPAGPIPYDASPFARERHVWLGLHAAATRSLGQGSMIIFS
>NZ_CP024985.1|WP_037686867.1|4620821_4621538_-|SLATT-domain-containing-protein
MQPEGPPRDPAEDGDGDLTGRPFPLGDWGEPAERLDELYRRVEADALRTAEWYLSDRAWKRRGARTLRAGAALGAVTGAAMPLLELTGSAPGAASYGYLSLLLAAACLACDRFFGLTSGWMRDVATAQAVQRRLQTLQFDWASENVREVLGPTEGTAGEAAERCLTVLRRFSEDITELVRSETADWMVEFRAGPAPLVMQSLGGAPARPDAYVPPARFPLPPGTRPNMPRQRPPEQPR
>NZ_CP024985.1|WP_078950239.1|4621823_4622168_+|YbaB/EbfC-family-nucleoid-associated-protein
MIPGGGQPNMQQLLQQAQKMQQDLAAAQEELALAEVEGQAGGGLVKATVTGSGELRALVIDPKAVDPEDTETLADLVVAAVQAANENAQALQQQKLGPLAQGLGGGSGIPGLPF
>NZ_CP024985.1|WP_030228593.1|4622228_4622828_+|recombination-protein-RecR
MYEGVVQDLIDELGRLPGVGPKSAQRIAFHILQAEPTDVRRLAHALLEVKAKVRFCAVCGNVAQEERCGICRDPRRDTTVICVVEEPKDVVAIERTREFRGKYHVLGGAISPIEGVGPDDLRIRELLARLADGTVTELILATDPNLEGEATATYLARMIKPMGLKVTRLASGLPVGGDLEYADEVTLGRAFEGRRLLDV
>NZ_CP024985.1|WP_030228590.1|4622820_4623468_+|DUF5063-domain-containing-protein
MSDATLHALGQDPDDFAASIADQIESFIVAVTEVAKGEDPDSAVPFLLLEVSQLLLAGGRLGAYQDVLPEERYEPDLGPEPDVDDLRERFALMLEPVDVYSEVFDPYEPRKAPVAHRISDDLADVVADLRHGLIHHQAGRITEALWWWQFSYFTNWGPTASATLRALQSLIAHVRLDQPLAALDGLDTDEDLTEEELAEQAGLVMAEELGRLGHK
>NZ_CP024985.1|WP_030228588.1|4623578_4624853_+|aspartate-kinase
MGLVVQKYGGSSVADAEGIKRVAKRIVDAKKNGHQVVVVVSAMGDTTDELIDLAEQVSPMPAGREFDMLLTAGERISMALLAMAIKNLGHEAQSFTGSQAGVITDSVHNKARIIDVTPGRIRTALDEGNIAIVAGFQGVSADSKDITTLGRGGSDTTAVALAAALDAEVCEIYTDVDGVFTADPRVVKKARKIDWIASEDMLELAASGSKVLLHRCVEYARRYNIPIHVRSSFSGLPGTWVSNENPQGDAQVEHAIISGVAHDVSEAKITVVGVPDKPGEAAAIFRAIADAEINIDMIVQNVSAASTGLTDISFTLPKTEGHKAIDALEKAKGQIGFDSLRYDDQIGKISLVGAGMKTNPGVTASFFQALSDAGVNIELISTSEIRISVVTRQDDVNDAVRAVHTAFGLDSDSDEAVVYGGTGR
>NZ_CP024985.1|WP_030228586.1|4624849_4625923_+|aspartate-semialdehyde-dehydrogenase
MTAPRSSGPALAVVGATGAVGSVLLQILSQRADVWGDIRLIASPRSAGRVLAVRGEETEVIALTEDAFDGFGKGDIVLFLTPAEVSARWAPVVTARGAVVVDQSAAFREDPEVPLVVPEVNGHAVRIRPRGIVAGPDCVTAAMIATLGALHAEYGLADLAVSSYQAASAAGRAGSEALRRQLSLVAGSTLGEQTGDVRRAVGEDTGPFAAPLALNVVPWSGELREGGWSSHELAVRAETRRILGLESLPIAVTCVQVPVVTGHSLTVRARFEREVDAGHAREILEAAPGVVLVDDPEAGEFPTPADAAGTDPAWVGRVRGSLDDSRSLEFFVCADNLRKGAALNATQISELIAGEFA

Crispr_ID: NZ_CP024985_20

• CRISPR_ID: NZ_CP024985_20
• CRISPR_location: 5130897-5130974
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_20

Consensus_repeat	Method
CGGCGTTTGAGGCGCGGGGCCCGGG	CRISPRCasFinder

spacers of NZ_CP024985_20

>20.1|5130922|28|NZ_CP024985|CRISPRCasFinder
GCGGAGCCCCAGGGGGCTGCAGCCCGGC

CRISPR arrays and Neighbor proteins around NZ_CP024985_20

CRISPR arrays

The CRISPR arrays of NZ_CP024985_20

>merge|NZ_CP024985|20|5130897-5130974|CRISPRCasFinder
CGGCGTTTGAGGCGCGGGGCCCGGGGCGGAGCCCCAGGGGGCTGCAGCCCGGCCGGCGTTTGAGGCGCGGGACCCGGG

>NZ_CP024985|20|21|5130897-5130974|CRISPRCasFinder
CGGCGTTTGAGGCGCGGGGCCCGGG	GCGGAGCCCCAGGGGGCTGCAGCCCGGC
CGGCGTTTGAGGCGCGGGACCCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030231715.1|5125178_5126912_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP024985.1|WP_030231729.1|5118364_5118901_+|acyl-CoA-thioesterase	unknown	unknown	gnl|CDD|224523
NZ_CP024985.1|WP_030231695.1|5135491_5135755_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_CP024985.1|WP_030231721.1|5122237_5123263_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133016
NZ_CP024985.1|WP_078950398.1|5141238_5141622_-|metallopeptidase-family-protein	unknown	unknown	gnl|CDD|240574
NZ_CP024985.1|WP_030231676.1|5142384_5143755_+|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl|CDD|236557
NZ_CP024985.1|WP_030231724.1|5120574_5121954_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP024985.1|WP_030231678.1|5141931_5142306_+|DUF3499-domain-containing-protein	unknown	unknown	gnl|CDD|378788
NZ_CP024985.1|WP_051841058.1|5116887_5118258_-|LCP-family-protein	unknown	unknown	gnl|CDD|224235
NZ_CP024985.1|WP_051841056.1|5134315_5134849_-|cysteine-dioxygenase	unknown	unknown	gnl|CDD|380416
NZ_CP024985.1|WP_030231700.1|5133288_5134248_-|2-phospho-L-lactate-transferase	unknown	unknown	gnl|CDD|237443
NZ_CP024985.1|WP_030231683.1|5139736_5141218_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_051841061.1|5123360_5125019_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP024985.1|WP_030231708.1|5129450_5130866_+|peptidoglycan-recognition-protein	unknown	unknown	gnl|CDD|128941
NZ_CP024985.1|WP_078950390.1|5127134_5128532_-|LCP-family-protein	unknown	unknown	gnl|CDD|367673
NZ_CP024985.1|WP_051841057.1|5119068_5120562_+|hypothetical-protein	unknown	unknown	gnl|CDD|227621
NZ_CP024985.1|WP_051841055.1|5136080_5139740_+|glycosyltransferase	unknown	unknown	gnl|CDD|224137
NZ_CP024985.1|WP_030231705.1|5131004_5131994_+|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl|CDD|223200
NZ_CP024985.1|WP_030231703.1|5131990_5133292_-|coenzyme-F420-0:L-glutamate-ligase	unknown	unknown	gnl|CDD|183957
NZ_CP024985.1|WP_030231710.1|5128560_5129310_-|TIGR03089-family-protein	unknown	unknown	gnl|CDD|274426

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030231715.1|5125178_5126912_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	4.64604e-54
NZ_CP024985.1|WP_030231729.1|5118364_5118901_+|acyl-CoA-thioesterase	gnl|CDD|224523	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism].	4.08405e-50
NZ_CP024985.1|WP_030231695.1|5135491_5135755_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	2.11886e-27
NZ_CP024985.1|WP_030231721.1|5122237_5123263_+|glycosyltransferase-family-2-protein	gnl|CDD|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	2.0436e-94
NZ_CP024985.1|WP_078950398.1|5141238_5141622_-|metallopeptidase-family-protein	gnl|CDD|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	5.15026e-28
NZ_CP024985.1|WP_030231676.1|5142384_5143755_+|phosphomannomutase/phosphoglucomutase	gnl|CDD|236557	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed.	0
NZ_CP024985.1|WP_030231724.1|5120574_5121954_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	2.69636e-56
NZ_CP024985.1|WP_030231678.1|5141931_5142306_+|DUF3499-domain-containing-protein	gnl|CDD|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	4.85777e-59
NZ_CP024985.1|WP_051841058.1|5116887_5118258_-|LCP-family-protein	gnl|CDD|224235	COG1316, LytR, Transcriptional regulator [Transcription].	4.32387e-55
NZ_CP024985.1|WP_051841056.1|5134315_5134849_-|cysteine-dioxygenase	gnl|CDD|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	3.1258e-21
NZ_CP024985.1|WP_030231700.1|5133288_5134248_-|2-phospho-L-lactate-transferase	gnl|CDD|237443	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional.	3.47275e-172
NZ_CP024985.1|WP_051841061.1|5123360_5125019_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	6.47433e-50
NZ_CP024985.1|WP_030231708.1|5129450_5130866_+|peptidoglycan-recognition-protein	gnl|CDD|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	5.35534e-47
NZ_CP024985.1|WP_078950390.1|5127134_5128532_-|LCP-family-protein	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	3.95985e-62
NZ_CP024985.1|WP_051841057.1|5119068_5120562_+|hypothetical-protein	gnl|CDD|227621	COG5305, COG5305, Predicted membrane protein [Function unknown].	1.13114e-25
NZ_CP024985.1|WP_051841055.1|5136080_5139740_+|glycosyltransferase	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	1.32656e-36
NZ_CP024985.1|WP_030231705.1|5131004_5131994_+|DNA-3-methyladenine-glycosylase-2-family-protein	gnl|CDD|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	7.16946e-28
NZ_CP024985.1|WP_030231703.1|5131990_5133292_-|coenzyme-F420-0:L-glutamate-ligase	gnl|CDD|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	0
NZ_CP024985.1|WP_030231710.1|5128560_5129310_-|TIGR03089-family-protein	gnl|CDD|274426	TIGR03089, conserved_hypothetical_protein, TIGR03089 family protein. This protein family is found, so far, only in the Actinobacteria (Streptomyces, Mycobacterium, Corynebacterium, Nocardia, Propionibacterium, etc.) and never more than one to a genome. Members show twilight-level sequence similarity to family of AMP-binding enzymes described by pfam00501.	1.58629e-74

Protein sequences

>NZ_CP024985.1|WP_030231708.1|5129450_5130866_+|peptidoglycan-recognition-protein
MRGFLASSIGVATAAALALPLALSTPALAAASEGAAAPVTPAGSTQSLPLAPLGPSGGRIPGVPGMSASPGGPEARGLAARDVKTFSLVGVVWDDAATRLVGRVQVRTRAAGTATWSGWQDVETHNGEHAADPDAVERGSRRVRGSTAPLWVGASDGIEVRVHAETGGEDTRAASRLPSGLRIELVDPGAAEPVAVLDGKNAGRPASPAGDDKGDAALVPEMTMEGAESSAANVPHATLGALEIGALNKADSTADAVLASDGALSAAARPFIGPRPRIVTRRGWGADESLRETGFVYTNTVKAAFVHHTASGNNYACKDAPAVLRSLYRYHVVSEGWRDIGYNFAVDRCGTVYEGRAGGVAKPVLGAHTMGFNADSMGIAVIGSFGGAAPPRAAVDAVARLTAWKLGLFGADPRAKTTLRSGGGNRFPKGTSVKMNVISGHRDGFATECPGKQLYNQLPPTRTTSAKLQGR
>NZ_CP024985.1|WP_030231710.1|5128560_5129310_-|TIGR03089-family-protein
MNATDRTPADLLRSALAADPGRPLVTFYDDATGERVELSVATFANWVAKTANLLQGDLAAEPGDRLALLLPAHWQSAVWLLACASVGVVAEVGGDPAGADLVVSGPDTLEEARACSGERVALALRPLGGRFPQPPAGFADYAVEVPGQGDRFAPFSPVDADAPGLVVGGEELSYAAVVERARADAAARGFGEGARVLSGLGYDSWEGLSSGLYGALATGGSVVLCRHLDRLSPQALEQRTESERVTHTV
>NZ_CP024985.1|WP_078950390.1|5127134_5128532_-|LCP-family-protein
MALYRAVPPGRPRHRGAGSAPGRTHPYGWRPVRRGDGTRVTDSAGIPGGTGAAGGGPRPPAGRRRRLLRWIGLGAVLLVLAGAATGWWLYEKLDGNITSDTSAEAELRRFERERPVHLADGAQNILLIGSDSRSGRENAGYGQDGGTQRSDTTILLHLAADRGSVTAVSIPRDLMTEVPACRAADGTRTAERFAQFNWAFQWGGAACTIRTVERLTGVRIDHHMVLDFGGFKQMVDAVGGVEVCLPQPVDDAEAHLRLPAGRHLLQGEQALGFVRARYGLGNGSDTERIQRQQQFLGSLVKKVQSNGVLLNPARLYPLLDAATSALTTDPGLASLRGLYELVRSVRDIPSDEVRFLTVPRRPYAPNPNRDELLEPDAGQLFQRLRLDRPVTVTPPVPTSTATPAPAPTAVSAVTSASSAAAAAEPVPLSPAELFRDAVRAESGTGSAPFPDPTFTGTTAGTAECR
>NZ_CP024985.1|WP_030231715.1|5125178_5126912_-|LCP-family-protein
MDAQSRGRADEIDPADQWVLNPRTGNYELRLGNSPAQQHSVSTPRRTRRTPSAPSAPSAPSPAVPKPRRGEGPPGGRRGGRPRGPAGGGASRRRRKALAVTGGTLAFLLVGGGLGSYLYYQHLNGNLKVIDTNGAGGSFKKDQPINILVIGTDKRSGAGNQGYGDAESVGHADTTILFHVSKDRSNATALSIPRDLITDIPVCPTKQPGGSVKQIAATKGSRFNNSLGQEGRDPGCTMRTVKQLTGIDVDNFMMVDFNAVKNLSTAVGGVPVCLAKDVNDRDSKLNLKAGEHRLQGEEALAFVRTRHSFGNESDLDRIKTQQQFLSSMMREMKSKETLTSPKKFFSLAEAATKSLTVDQGLGSIGKLTDLAGELKDMNLKNVTFTTLPVVDNPNEPSNRKATVVVNSSQADPLLQMIREDVSLTEVEKKEHAAKEAADAKQDALLQGNRAPAGDVRVDVYNGGGPPGSASTTLTWLQNAKGVYKASNHGNAAERLAATQLEYAPNQADQARALADMMGLSAAAMKVGTVDAGPKTPMKLTLGSDFKEPGTPLGAPAAPQQAPEGLQRVEADKAVCAK
>NZ_CP024985.1|WP_051841061.1|5123360_5125019_-|LCP-family-protein
MSGGGTGASGAVPPPRSGQGGARPAGGGGTPVRRKRRRVLFWVASVLAFLILGTSAAGYLYYRHLDGNIRSGQRLSGESGVEKTHANAKGQRPLNILLIGSDSRNKPENVELGGSSDTVGNPPLADVQMLLHVSADRENASVVSIPRDTRVDIPECTDPKTGEKFKKTNAMINESLGRGGPGCTLATWERLTNVYIDHWMMIDFSGVVQMADAIGGVPVCVKDNVWDRPLPTSGGGSGLKLQKGTTRVKGEQALQWLRTRHAFSSDLGRAQAQHMYMNSMMRELKSQNAFTDVGRITDLAEAGTKALEVSEEIGSVKKLYNLAMQLKDVPTNRITMTTMPTFQDPRDVDRLIVNPADADKLWTMLRKDVAFDKNGDPQTPQSPSASAPAPGASQPAPQGSQQPVQPSQEPSKAPATTPDKIPVNVVNGTAAGQPLAPHRANAISEVLVSKGFTGARADSALTPEKTTVVRYPTPDLADEAQSVAASLGIPNTAVQQSADVSKITLVVGADWREGNAFPAQTPPAAGAIPDTADAINGSDTGACMDVYKPYRW
>NZ_CP024985.1|WP_030231721.1|5122237_5123263_+|glycosyltransferase-family-2-protein
MPAQQPAVSVIMPVLNEERHLRDSVRHILGQEYAGEMEVVIALGPSTDRTDEIAAELVREDPRVHTVPNPTGRTPAALNAAIKASRHPIVVRVDGHGMLSPNYIATAVRLLEETGAQNVGGIMHAEGENAWEDAVAAAMTSKIGVGNAAFHTGGQAGPAETVYLGVFRREALEQQGGYNEEFIRAQDWELNFRIREAGGLIWFSPELKVQYRPRPSVRALAKQYKDYGRWRHVVARYHAGSINLRYLAPPTAVCAIAAGVVAGVAVSPWAFAVPAGYLAAITAGSVPAGRGLPLKARAQIPVALATMHMCWGYGFLTSPRSLARKVIASRRPSVRHDPSQV
>NZ_CP024985.1|WP_030231724.1|5120574_5121954_-|LCP-family-protein
MRIAAVLSLVVLGSGAVGHAVMTGLDTGIERVDPFKDMKNRPQAGHGVNFLLVGTDGREKITPEEKREYRLGGAPCHCTDTVMLVHLSADRERASVISLPRDSYAEVPAHQDLVTGTAHKAHPVKLNAAYAEGGPNLTVRTVENMTRVKIDHYLEVDFTSFMKTVDAMGGVEICTAKAMHDTYTGLDLLPGTHRLTGGQALQYVRSRHVDGASDLGRMQRQQRFIAALIKQATGGGVLLNPVKFKEVSSTLLGSVRADRGFGSEQMLALGQAMRGFTPSSSEFASVPVGDPSFQVKGIGSTVKWDEPKAAKLFEALRQDQPLAPARPGQAPHGPAPVPVDVPPKQIRVQVENGTRIDGLGGRVDAALRATGFDTTQAPATGASREVRRTVIVYDPRWDRSARTVSTALPGSELRAVAGQGRTVLVIAGADFKKVVPVRAEDPYQGEFGVVTGDQVVCGS
>NZ_CP024985.1|WP_051841057.1|5119068_5120562_+|hypothetical-protein
MPTATQTTTAAASAPARAGARRPTGPDWLWAALLTLAVTAFRGGTPQLWRDELASWNAASRSTGELLAMLGHVDAVSGLYYLLLHGWVSVFGDSAAMLRLPSALAMAGSAALVVLTARALFDRRTAVFAGLLFALLPVVTRYGTEARSYAFVVLAVCAATWLLLRALERPRPGRWAGYAVAVAAAGLLHMVALLFLLPHAMVVALRWWRDRRGRTLLSFVLAAAAGLLPVIPLVLLGRQQVGRQISWIKTPRLRDIAGLWDNLFASPLVALAVAALALLPLAWSRGRRPAVELMLLGAVPILAVYVVSQGSTSYFIDRYVLFTVPAWAVLAAAGLAALKPRAAGAAGLAALVLLGVPDQRHLRTEQAKETSDGRAAARVIAQGYRPGDGFVPVRGADRVYMVDFQIAYYLPGRVHLHDVFAARSALDADDLFPQECERPEQCLGDTRRIWLVTRGTGKADPYSRLPAEQVRALKGHYRVASTTEVRGLHVSLLERTG
>NZ_CP024985.1|WP_030231729.1|5118364_5118901_+|acyl-CoA-thioesterase
MTEIPPVPAGKPISASRTTLSHIMTANDTNLLGTVHGGVIMKLVDDAAGAVAGRHSGGPAVTASMDEMAFLAPVRVGDLVHVRAQCNWTGRSSMEIGVRVLAERWNESTPATQVGSAYLVFTAVDSDGKPRQVPPVLPETEQDERRYQEAQIRRTHRLARRQAITELRERRAAEGLDD
>NZ_CP024985.1|WP_051841058.1|5116887_5118258_-|LCP-family-protein
MSDWDGWNGERDARGRRDDGYGRGSGQPQPEGAQRMRHVQRQPQPPQRPAQPPQRPGRPPVPPQGPPRGRPAGGVPPQQTQGPDAAYDSGYNTGQVYGRPQGPGGPAGPGRPGRPGGPSRPGGPGGPAGPAPDWRRRIKIGSIVLVSALLVTSIGTYFWADSKVRREVDLSKVIERPKEGDCTTYLIVGSDSREGMSDEEKKKLHTGSAEGKRTDSMMVLAKCSSGNTMISLPRDSDVEIPSFVGSQSGKKFPSQGRRVKLNAAYAEDGPELLVRTIEFNTGLHIDHYAEIGFAGFANIVDALGGVELDIEQGFKDEKSGADFKAGRQTLNGEQSLAFVRTRYAFAESDLQRTKNQQKFLSALASQAATPGTILNPFALYPVMGAGLDTLVVDKDMGLWDLGQMFFAMKGITSGDGVSMNMPISGQKGGNLVWDKAKVQQLVKEIQNDQKVTVRGQ
>NZ_CP024985.1|WP_030231705.1|5131004_5131994_+|DNA-3-methyladenine-glycosylase-2-family-protein
MAGRFDPLTRTAVRGGRTDVPPGAATPAGGGSRRRWSPGGPVDLGLILGPLRRGPADPTFRVTPDGSVWRATRTPQGPATLRIGRAGEEVEGEAWGPGAEWALAELPRLLGADDDPAAFVPRHRLVHASHRRRPGLRLTRTGLVLESLVPVVLEQKVTSDEAYRSWRRLVRRYGEPAPGPQELWVMPDARTWALIPSWDWHRAGVDAKRSATIVRAARVADRLEEAAAMDLPRAAARLEAVPGIGPWTSAETLQRSNGAADALTTGDLHLPGIVGYALTGERDADDERMLELLAPYEGQRHRAARLILLAGRTPPRRAPRMPRGDIGRL
>NZ_CP024985.1|WP_030231703.1|5131990_5133292_-|coenzyme-F420-0:L-glutamate-ligase
MTLPAPSYEVRALAGIPEVRPGDDLAALIAGTSPGLRDGDVLLVTSKIVSKAEGRIVTAASREEAIDAETVRVVARRGALRIVEDRRGLVMAAAGVDASNTAPGTVLLLPEDPDASAARIRAGLRELLSVDVGVIVTDTFGRPWRSGLTDVAIGAAGVRVLDDLRGGTDAHGNPLSATVVATADELAAAGDLVKGKAAGLPVAVVRGLGHVRGEGSSARDLVRAPADDMFRLGTSEAVREAVTQRRTVRDFTDEPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESAAARRELLDAMRDAWIADLRADGRSEESIAKRVRRGDVLRRAPYLVVPCLVTDGAHDYGHARRDAAEREMFVVAMGAGVQNFLVALAGERLGSAWVSSTMFCRDVVRKVLALPQDWDPMGAVAVGHPAAAPAPRPGRAADAFVEVR
>NZ_CP024985.1|WP_030231700.1|5133288_5134248_-|2-phospho-L-lactate-transferase
MRIVVLAGGIGGARFLRGLLSAVPDAEITVIGNTGDDIHLFGLKVCPDLDTVMYTLGGGINEDQGWGRTDESFTVKEELAAYGVGPTWFGLGDRDFATHIVRTQMLGAGYPLSAVTEALCDRWQPGVRLLPMSDDRVETHVAITDPESGERRVVHFQEYWVRMRAAVDAEAVVPVGAEQAKPAPGVLEAIAAADVILFPPSNPVVSVGTILAVPGIREAVAAADAPVVGLSPIVGGAPVRGMADKVLAAVGVEATAAAVALHYGTGLLDGWLVDTADADAVAEVEAAGITCRAVPLMMTDTEATAAMARAALELAEASR
>NZ_CP024985.1|WP_051841056.1|5134315_5134849_-|cysteine-dioxygenase
MNSAPAATSPITAAVIESDLQIAGDILAVQHLLQPAREHPATVAEFAGLARSIAEDRAGWEHLVRYDATTRWYHRLRTGPGYEVWLLSWVPGQGSGRHGHGGSSGVLTVLDGELTEHSARGPLALGPGSQRVFAPGYSHEVVNDTLDGAVSLHVYFPGLTEMPMHSCSPARGEHVPA
>NZ_CP024985.1|WP_030231695.1|5135491_5135755_+|WhiB-family-transcriptional-regulator
MTELFQELLVEEADEELGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRSECLEYGLANDERFGIWGGLSERERRRLKKAAV
>NZ_CP024985.1|WP_051841055.1|5136080_5139740_+|glycosyltransferase
MSLHSNSTASHQAAATPEFPRHVVTAVLVAHDGARWLPQTLAGLLAQERPPQSHVAADTGSADDSARLLDQAFGDDRVLHLARRTGFGAAVDEAVRSAAVLTAEDLPYLKRPSGWDPVSRTWRDDAYDLPDLPHGEPVQWLWLLHDDSAPEPDALAELLRVADENPDAAVIGPKLRGWYDKKQLLEAGVTIARSGRRWTGLDRREQDQGQHDQVRPVLSVSTAGMLVRRDVYDALGGFDRRLPLMRDDVDLCWRAHSAGHTVLVAPDAVLRHAEAAARERRTVDCAGRSAVDPHRVDKAGAVYTLLANCSGRALPYVLLRLVLATLLRTLGYLVGKAPGQAVDEFTGLLATLLRPGRILAARKARRRPAVPAADLRPLFPPPGATLRAGAEQLAGHFGSGQGADTAPAGRHGGAVESGPGGDDADYLEIEQFGRLKRIARRPAPVLFALLLLVSLAACRALIGGGTLMGGALLPAPPGALDLWHAYTGDWQPVGLGTTAGAPPYLAVLAAFAAPLLGSTKAALTLLLVCSVPLCGLTAYFASRPLVPSRLLRAWAAVAYAFLPAVTGALAGGRLGTAVLAVLLPLLARSAVAAFGFADRESTGSWRAVWTYTLLLTLTTAFTPVVWPLAAVLGTGALLVRRARWKAYAPRLLATLAVPLAVLAPWSLGLLTHPARFLREAGLPYGSGSATALGLLGASPGGPGTTGGLLFAGTVLAALAALLRADRRFAVAVAWTTALTALFLAVLLNRDGWAGPATLVQGLALIAAAVVGADGARERVAARSFGWRQPLAALVALGAALGPLLLAAVWTVAGADGPLGRRDPVQVPAFVAAQSDDSNRTRTLVLGGDSPATVSYTLVRGSGVRLGDAELLAEAGSGPRLAQAVSSLVSGSGADQSEQLGAFAVRYVMIPPGGSPAMRRTLDGTPGLRQRHQDDGTAIWEVQRLPARVAILPGKQGQATVAVDAGPVEAHAKVPAGEEGRTLRVADRADAGWHATLDGKPLKPKALEGRDAWAQGFALPREGGRLALVHTDSLARDAWHWTQGLLALVLLVMALPGRRARLDDDLPEEDAAPAGDGAGAAVPGQGRRARRAAPAEPAPDPAPAEAVADPYAQIPAQQVYGEESYAYQEPWSPYADGQQAQQPHQAEQGDPYAQPYAQPYTQPYAAPPHPDAQHPGAQQPYGHGQQFGFPQQQPPHPYEYDQPYDTYGQHDPRPDGSPQQ
>NZ_CP024985.1|WP_030231683.1|5139736_5141218_+|hypothetical-protein
MKQRAPLTLAAVTAALAAACGLAVLTAPAATPAGGTGGPPAARMPVERSVLVCPAPSASDIAETTYTSLTPGKGGGKGTARLLTKEGKTVLQPKEPGRPVGATASGAEAPALTGTADGVLAPGWTAQQTTKVAVGQTRGLLGVACTAPGTDFWFPGVSTAKGRQDYIHLTNPDDTVAEVDIKLYGPDGLVKGKPGTADTVIAVDPRSTTKVLLSSLAPDAPLTDVTAHVTTGSGRVGASAQIGEDGVGADWLPASAGPAGSAVLPGIPADATSVRLVAFAPGEDDADLRLKLAGPTGSISPAGAEQLHLKAGMTASVDLKDVTRGEAGSLLLAPADPKKAVPVVAALRVVRGTGTKQELGFIPAAAPVGARATVADDRLDDKATALALTASGGADAKVRVTASAGTEGGEGAVKEVTVKAGTTLAVTPPPAPAGGKGAYALTLETLSGGPVHAARTLTLPHEGIPMFTVQTFGDDRSTVAVPRAVEDPSILVR
>NZ_CP024985.1|WP_078950398.1|5141238_5141622_-|metallopeptidase-family-protein
MRGPLAPPQVPLSASRAELFGDLVRDSVERLERRWAQLAEVEFVIADVPGPPGGPDAGWNDEAVPLGGLIDARDGRPARIVVFRRPVEIRAKTRDERALLVHEIVVEQVAELLGLSPETVDPRYGQD
>NZ_CP024985.1|WP_030231678.1|5141931_5142306_+|DUF3499-domain-containing-protein
MSLVRRCSRTACGRPAVATLTYVYADSTAVLGPLATYAEPHCYDLCAEHSERLTAPRGWDVVRLSDGSGPSRPSGDDLEALANAVREAARPPERAAEAGGSGQGPQVTGETRRGHLRVLRSPDS
>NZ_CP024985.1|WP_030231676.1|5142384_5143755_+|phosphomannomutase/phosphoglucomutase
MAADLSNIVKAYDVRGVVPDEWDEPLAELFGAAFVEVTGATAIVVGHDMRPSSPGLSGAFARGAAARGVDVTLIGLCSTDQLYYASGKLDLPGAMFTASHNPAQYNGIKLCRAGAAPVGQDTGLATIRELAEKWTDEGAPAIPAGTVPGTVTELDSLPGYAEHLKGLVDLTSIRPLKVVVDAGNGMGGHTVPTVFEGLPLDLVPMYFELDGTFPNHEANPLDPKNIVDLQARVIAEGADLGLAFDGDADRCFVVDERGEGVSPSAITALVAARELARNGGTGTVIHNLITSWSVPEVVREHGGTPVRTRVGHSFIKAEMASSGAIFGGEHSAHYYFKDFWNADTGMLAALHVLAALGGQEGTLSALVAEYDRYVGSGEINSTVADQAGRTAAVKAAYASQEGVTFDELDGLTVSAADWWFNLRPSNTEPLLRLNVEARDEATLAKVRDEVLALVRA

Crispr_ID: NZ_CP024985_21

• CRISPR_ID: NZ_CP024985_21
• CRISPR_location: 5411525-5411620
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_21

Consensus_repeat	Method
GAGCCGTTTCCGGACGGGGGTGCCGGGCCG	CRISPRCasFinder

spacers of NZ_CP024985_21

>21.1|5411555|36|NZ_CP024985|CRISPRCasFinder
GGGTCCGGGGTGGATCCGGATCCTGAGCCTGACCCC

CRISPR arrays and Neighbor proteins around NZ_CP024985_21

CRISPR arrays

The CRISPR arrays of NZ_CP024985_21

>merge|NZ_CP024985|21|5411525-5411620|CRISPRCasFinder
GAGCCGTTTCCGGACGGGGGTGCCGGGCCGGGGTCCGGGGTGGATCCGGATCCTGAGCCTGACCCCGAGCCGTTTCCGGACGGGAGTGCCGGGCCG

>NZ_CP024985|21|22|5411525-5411620|CRISPRCasFinder
GAGCCGTTTCCGGACGGGGGTGCCGGGCCG	GGGTCCGGGGTGGATCCGGATCCTGAGCCTGACCCC
GAGCCGTTTCCGGACGGGAGTGCCGGGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030229540.1|5417060_5418353_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229549.1|5422088_5422625_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229522.1|5405016_5407287_-|copper-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319783
NZ_CP024985.1|WP_037687113.1|5400107_5400653_-|DUF937-domain-containing-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229547.1|5421262_5422039_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP024985.1|WP_030229529.1|5408270_5409296_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP024985.1|WP_030229538.1|5415944_5416976_-|DUF916-domain-containing-protein	unknown	unknown	gnl|CDD|368712
NZ_CP024985.1|WP_030229524.1|5407381_5407615_-|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|225328
NZ_CP024985.1|WP_030229551.1|5422893_5423367_+|hypothetical-protein	unknown	unknown	gnl|CDD|370266
NZ_CP024985.1|WP_030229526.1|5407801_5408002_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133414
NZ_CP024985.1|WP_037687114.1|5420479_5421181_-|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl|CDD|225002
NZ_CP024985.1|WP_030229530.1|5409315_5410230_-|TIM-barrel-protein	unknown	unknown	gnl|CDD|275172
NZ_CP024985.1|WP_030229515.1|5399498_5400038_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP024985.1|WP_030229520.1|5403369_5404659_+|citrate-synthase	unknown	unknown	gnl|CDD|180164
NZ_CP024985.1|WP_030229534.1|5412351_5414226_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	unknown	unknown	gnl|CDD|275170
NZ_CP024985.1|WP_030229544.1|5419971_5420382_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP024985.1|WP_030229518.1|5400939_5403186_+|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl|CDD|273632
NZ_CP024985.1|WP_078950287.1|5410275_5411301_+|5-dehydro-2-deoxygluconokinase	unknown	unknown	gnl|CDD|275175
NZ_CP024985.1|WP_030229542.1|5418571_5419942_-|S8-family-peptidase	unknown	unknown	gnl|CDD|173790
NZ_CP024985.1|WP_030229536.1|5414236_5415736_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143404

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030229551.1|5422893_5423367_+|hypothetical-protein	gnl|CDD|370266	pfam09056, Phospholip_A2_3, Prokaryotic phospholipase A2. The prokaryotic phospholipase A2 domain is predominantly found in bacterial and fungal phospholipases, as well as various hypothetical and putative proteins. It enables the liberation of fatty acids and lysophospholipid by hydrolysing the 2-ester bond of 1,2-diacyl-3-sn-phosphoglycerides. The domain adopts an alpha-helical secondary structure, consisting of five alpha-helices and two helical segments.	6.87936e-49
NZ_CP024985.1|WP_030229536.1|5414236_5415736_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_CP024985.1|WP_030229522.1|5405016_5407287_-|copper-translocating-P-type-ATPase	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP024985.1|WP_030229547.1|5421262_5422039_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.23893e-19
NZ_CP024985.1|WP_030229529.1|5408270_5409296_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.6742e-57
NZ_CP024985.1|WP_030229538.1|5415944_5416976_-|DUF916-domain-containing-protein	gnl|CDD|368712	pfam06030, DUF916, Bacterial protein of unknown function (DUF916). This family consists of several hypothetical bacterial proteins of unknown function.	1.36303e-11
NZ_CP024985.1|WP_030229524.1|5407381_5407615_-|heavy-metal-associated-domain-containing-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	8.54022e-11
NZ_CP024985.1|WP_030229526.1|5407801_5408002_-|MarR-family-transcriptional-regulator	gnl|CDD|133414	cd04787, HTH_HMRTR_unk, Helix-Turn-Helix DNA binding domain of putative Heavy Metal Resistance transcription regulators. Putative helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR), unknown subgroup. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules, such as, metal ions, drugs, and organic substrates. This subgroup lacks one of the conserved, metal-binding cysteines seen in the MerR1 group.	0.000336798
NZ_CP024985.1|WP_037687114.1|5420479_5421181_-|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl|CDD|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	5.27481e-28
NZ_CP024985.1|WP_030229530.1|5409315_5410230_-|TIM-barrel-protein	gnl|CDD|275172	TIGR04379, myo-inositol_catabolism_protein, myo-inosose-2 dehydratase. Members of this family include the enzyme myo-inosose-2 dehydratase, product of the gene iolE, as found in inositol utilization cassettes in many species. [Energy metabolism, Sugars].	1.50382e-42
NZ_CP024985.1|WP_030229515.1|5399498_5400038_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.53153e-14
NZ_CP024985.1|WP_030229520.1|5403369_5404659_+|citrate-synthase	gnl|CDD|180164	PRK05614, gltA, citrate synthase.	0
NZ_CP024985.1|WP_030229534.1|5412351_5414226_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	gnl|CDD|275170	TIGR04377, 3D-35/4-trihydroxycyclohexane-12-dione_hydrolase, 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase. Members of this protein family, 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase (iolD), represent one of eight enzymes in a pathway converting myo-inositol to acetyl-CoA. IolD hydrolyzes the cyclic molecule 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione to yield 5-deoxy-D-glucuronic acid. TPP is a cofactor. [Energy metabolism, Sugars].	0
NZ_CP024985.1|WP_030229544.1|5419971_5420382_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.411e-16
NZ_CP024985.1|WP_030229518.1|5400939_5403186_+|ATP-dependent-RecD-like-DNA-helicase	gnl|CDD|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP024985.1|WP_078950287.1|5410275_5411301_+|5-dehydro-2-deoxygluconokinase	gnl|CDD|275175	TIGR04382, myo-inositol_catabolism_protein, 5-dehydro-2-deoxygluconokinase. All members of the seed alignment for this model are translated from the iolC gene of known or putative inositol catabolism operons. Members with characterized function are 5-dehydro-2-deoxygluconokinase, the enzyme catalyzing the fifth step in degradation from myo-inositol or closely related compounds. Note that many members of this family are fusion proteins with an additional C-terminal domain, of unknown function, described by pfam09863. [Energy metabolism, Sugars].	3.62976e-141
NZ_CP024985.1|WP_030229542.1|5418571_5419942_-|S8-family-peptidase	gnl|CDD|173790	cd04077, Peptidases_S8_PCSK9_ProteinaseK_like, Peptidase S8 family domain in ProteinaseK-like proteins. The peptidase S8 or Subtilase clan of proteases have a Asp/His/Ser catalytic triad that is not homologous to trypsin. This CD contains several members of this clan including: PCSK9 (Proprotein convertase subtilisin/kexin type 9), Proteinase_K, Proteinase_T, and other subtilisin-like serine proteases. PCSK9 posttranslationally regulates hepatic low-density lipoprotein receptors (LDLRs) by binding to LDLRs on the cell surface, leading to their degradation. The binding site of PCSK9 has been localized to the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR. Characterized Proteinases K are secreted endopeptidases with a high degree of sequence conservation. Proteinases K are not substrate-specific and function in a wide variety of species in different pathways. It can hydrolyze keratin and other proteins with subtilisin-like specificity. The number of calcium-binding motifs found in these differ. Proteinase T is a novel proteinase from the fungus Tritirachium album Limber. The amino acid sequence of proteinase T as deduced from the nucleotide sequence is about 56% identical to that of proteinase K.	1.60143e-111

Protein sequences

>NZ_CP024985.1|WP_078950287.1|5410275_5411301_+|5-dehydro-2-deoxygluconokinase
MGRERGAGGTAQVAGDAEVSAVNSADGSAYDLITMGRIGVDLYPLKTGVPLGEADTFGRFLGGSPTNVAVAAARLGRRTAVITRTGADPFGAYLRAELRGFGVDDRWVGEVERYPTPITFCEVFPPDHFPLYFYRLPKAPDLEIGADEVDLEAVRAARVFWMTGTGLSAEPSRSATLGALEARSKSGTTVFDLDWRPMLWEEPPGPWYERALALATVAVGNTEECAVATGRDEPYAAARALLDAGVELAVVKRGPQGVLAVHRDGTVVEVPPVPVTVVNGLGAGDAFGGALCHGLLAGWDLERVLRHANAAGAIVASRLACSTAMPFPDEVEEVLGRAGGV
>NZ_CP024985.1|WP_030229530.1|5409315_5410230_-|TIM-barrel-protein
MTSSPPALTRIRVGSAPDSWGVWFPEDPLQTPWERFLDEVADAGYEWIELGPYGYLPTDAARLADETAKRGLRVSAGTVFTGLHHGPAVWEQTWEHVSRIAALTQDTGAEHLVVIPSFWRDDKTGAVLEDRVLTPDQWRELTSQTERLGREVRDRYGLRIVVHPHADTHIDTPANVARFLDATDPALVSLCLDTGHYAYCGGDSVEAIETFGERIGYLHLKQVDPRVLAEVRAEELPFGPAVARGVMCEPPSGVPALEPVLAAAQRLGVELFAIVEQDMYPCPPDRPLPIARRTRAHLRSCGAR
>NZ_CP024985.1|WP_030229529.1|5408270_5409296_-|Gfo/Idh/MocA-family-oxidoreductase
MSGTLGIAVIGTGRMGSDHVRRIGTTVGGARVVAVADPDGDRVKEVAAGLEGAGAYTDPGAAIAAPGVDAVLIASPGPAHEEAVLQALERRLPVLCEKPLTPDPEGALRIMEAERRLGRRLVQVGFMRRFDAEYERLKELLDAGGIGRPLFLHCRHRNASSPAFFTGDMLISDSVVHEVDAARWLLGQEVTAVTVLAPTPTSAAPQALGDPRFVLLETSGGAIVDVEIFVNCGFGYQVRCEAVGESGTARIGDGHAMVVESGGRWGGEVVQDYTTRFADAYDRQVRRWVAAAARGRVAGPDAWDGYAAAAVSRAGLAAARDGVRTEVRLVERPELYAAGRD
>NZ_CP024985.1|WP_030229526.1|5407801_5408002_-|MarR-family-transcriptional-regulator
MSDRTLWSYKEIAAHIQVQPDTVRSYRKHGLLPAPDHVEGSKPYWYADTIRAWVARRPGNRGRREG
>NZ_CP024985.1|WP_030229524.1|5407381_5407615_-|heavy-metal-associated-domain-containing-protein
MTAETDTQTTAVYKVTGMTCGHCEGAVTAELTALAGVSSVKAAAATGEVTVVSAAPLAEEDVRAAVDEAGYELAGRV
>NZ_CP024985.1|WP_030229522.1|5405016_5407287_-|copper-translocating-P-type-ATPase
MTSTVHDGPITAVELTIGGMTCASCAARIEKKLNRMDGVEATVNYATEKAHVSCTGDVRVADLIATVVRTGYTAEEPAPPPPAAADGAGPEREAEAPAGRDPEPAALRQRLLVSAVLAVPVVVLAMVPALQFDNWQWLSLTLAAPVVVWGGFPFHKAAWTNLRHGAATMDTLVSIGTLSAFAWSLWALFFGHAGMPGMRHGFDVGVSRSDGSSAIYLEVAAGVVTFILLGRYLEARSKRKAGAALRALLELGAKDVVVLRAGREVRIPVAALAVGDRFVVRPGEKIATDGTVVEGSSAVDASMLTGESVPVEVAVGDAVTGATVNASGRLVVEATRIGADTQLARMAKMVEDAQNGKAAVQRLADRVAGVFVPVVLLLALGTWVAWLLITDDATAAFTAAVSVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLESTRRVDTVVLDKTGTVTTGRMTLSAALPAEGVDPGELLRLAGALEHFSEHPIARAVAAAAADATGGLPVPEGFRNHGGLGVEGTVEGHAVLVGRERLLADRSVALPAALAEAKEAAEAAGATAVLVAWDGTARGLLSVADAVKGTSAEAVTRLRALGLTPVLLTGDNRAVAETVAREVGIDEVIAEVLPQDKVDVIRRLQSEGRTVAMVGDGVNDAAALAQADLGLAMGTGTDAAIEAGDLTLVRGDLRVAADAIRLSRRTLSTIKGNLFWAFGYNLAALPLAAAGLLSPMIAGAAMAFSSVFVVTNSLRLRSFR
>NZ_CP024985.1|WP_030229520.1|5403369_5404659_+|citrate-synthase
MSDNSVVLRYADGEYTYPVVESTVGDQGFDISKLRAQTGLVTLDSGYGNTAAYKSAITYLDGEQGILRYRGYPIEQLAERSTFIEVAYLLINGELPTVDQLASFRNEITQHTLLHEDVKRFYDGFPRDAHPMAMLSSVVSALSTFYQDSHNPFDEKQRHLSTIRLLAKLPTIAAYAYKKSVGHPVVYPRNDLGYVENFLRMTFSVPAQEYDLDPVVVSALDKLLILHADHEQNCSTSTVRLVGSSQANMFASISAGISALWGPLHGGANQSVLEMLEGIKNDGGDVDAFIRKVKNKEDGVRLMGFGHRVYKSFDPRAKIIKAAAHDVLSALGKSDELLDIALKLEEHALADEYFVSRNLYPNVDFYTGLIYRAMGFPTEMFTVLFALGRLPGWIAQWHEMIKEPGSRIGRPRQIYTGEVLRDFVPVEAR
>NZ_CP024985.1|WP_030229518.1|5400939_5403186_+|ATP-dependent-RecD-like-DNA-helicase
MTTNGAVQLAVVEGVLERITYANEESGYTVARVDTGRGAGDLLTVVGSLLGAQPGESLRMEGRWGSHPQYGKQFSVENYSTLLPATIQGIRRYLGSGLIKGIGPKIADRIVEHFGTDTLDVIEAEPKRLIEVPGLGPKRTKMIGAAWEEQKAIKEVMVFLQGVGVSTSIAVRIYKKYGDASISVVRNQPYRLAADVWGIGFLTADRIAQAVGIPHDSPERVRAGLQYALSQSTDQGHCFLPEERLIADGVKLLQVDTGLVIECLAELAADPEGVVRESVPDPQGGPDPLTAVYLVPFHRAELSLVGQVRRLLNAEEDRMPGFRDVDWDKALGWLAGRTGASLAPEQRDAVRLALTRRVAVLTGGPGCGKSFTVRSIVELARAKKAKVVLAAPTGRAAKRLSELTGAEASTVHRLLELKPGGDAAYDRDRPLDADLVVVDEASMLDLLLANKLVKAVAPGAHLLLVGDVDQLPSVGAGEVLRDLLAEGGPVPAVRLTRIFRQAQQSGVVTNAHRINTGVPPITDGLPDFFLFPEEDTEAAGLLAVDVAARRIPARFGLDPRRDVQVLAPMHRGPAGAGNLNGLLQQAITPARPNLPEKRFGGRVFRVGDKVTQIRNNYEKGANGVFNGTVGVVTALDLDEQRLTVRTEEDEEVGYEFAELDELAHAYAVTIHRSQGSEYPAVVIPVTTGAWMMLQRNLLYTAVTRAKKLVVLVGSRKALGQAVRTVSAGRRYTAVAARLSGRIPVGNIT
>NZ_CP024985.1|WP_037687113.1|5400107_5400653_-|DUF937-domain-containing-protein
MSESSFQDDVLGELGDEKLTEIAGLLGTDTDGARAAVSETVGAMAGGLQEKAAAEGEDGEVGQAVAEAAEPPLQGVATLGGLGGLLGGGMMAGVLAKVSKPVANAVAKKTGIPAATVSRVIEVLIPVVLAVFAKRAAEGKAGAGGAPSAGGAPAPGAAPAAGAGGGGLGDLLGQILGGGKK
>NZ_CP024985.1|WP_030229515.1|5399498_5400038_-|GNAT-family-N-acetyltransferase
MKPPALPEDSPGRPVRLRDPEPGDLGWIVQRHGALYAAEYGWNQEFEGLVARIVADFAGDHDPYLERVWIAEHEGRPVGSVMCVREEGAPGTARLRLLLVEPAARGLGVGARLVDAVVAFARSVGYRELVLWTNDVLVSARSLYLRAGFTLVTERAHRSYGADLTGQDWRLALREDAPR
>NZ_CP024985.1|WP_030229534.1|5412351_5414226_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)
MRLTTAQALVRFLARQYTERDGRRHRLIAATWGIFGHGNVAGIGQALLESGPEAMPFLQGRNEQAMVHAAVGYARQSGRLSAHAVTTSIGPGATNLVTGAALATINRIPVLLLPGDTFATRPADPVLQQLEVPYAGDLSVNDTLRPVSRHFDRITRPEALVPAALQAMRVLTDPVQTGAVTLALPQDVQAEAHDWPEEFFAERVWTVRRPRPDRRELAAAAEAVRGSARPLIVAGGGIRHAAAGDALAALAEATGIPVATTQAGKGVLPYDHPAEVGGVGHTGTATADALAREADLVIAAGTRLTDFTTASSTLFQNPAVRFLGLNLDPYDAHKLAALPLVADAREGLAELLEAVAGYRVAPAYEAAYTEAKAGWEARVDAAYAVPADEEDLPPTQAQVLGLLDGLVDGTDILVNAAGSLPGDLHKLWRARSADQYHVEYGYSCMGYEIPAALGTALAAPGRPVWALVGDGTYLMNPTELVTAVQEGVPVKVVIIDNQGFASIGGLSGAVGGEGFGTAYRFRGPGGAYDGAPLPVDLAANAASLGMATIRTRTIGDLRKALSEARAADRPTCVYAQTRTPDTVSGPPPAQAWWDVPVAETATRASAALARDEYDRQAAQRRRHL
>NZ_CP024985.1|WP_030229536.1|5414236_5415736_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MKTVNHWIGGKTVEGASGNYGPVTDPATGEVTTQVALASAEEVDAAVRVAQEAFLSWGQSSLAARTKVLFAYRALLDANRDAIAELIVAEHGKVHSDALGEVARGLEIVELACGITTQLKGELSTSVSNRVDVSSIRQPLGVVAGITPFNFPAMVPMWMFPLAVACGNTFILKPSEKDPSAANKLAELMTEAGLPAGVLNVVHGDKVAVDALLAHPGISAVSFVGSTPIARHIHTTASANGKRVQALGGAKNHMLVLPDADLDAAADAAVSAAYGSAGERCMAISAVVAVGSIADELVEKIRERAEKIKIGPGNDPTSEMGPLITAAHRDKVASYVKGAAAQGADVVLDGTGYTVEGNENGHWIGLSLLDNVRTDSDAYRDEIFGPVLCVLRTETYEEGVALINASPFGNGTAIFTRDGGAARRFQLEIQAGMVGVNVPIPVPVGYHSFGGWKDSLFGDHHIYGNDGIHFYTRGKVVTTRWPDPADAPAGVDLGFPRNH
>NZ_CP024985.1|WP_030229538.1|5415944_5416976_-|DUF916-domain-containing-protein
MRLRTLPHVLLAGLCGLLLLPALSAAPATAADNGTWGVFPTPAAGAAMTDRAYFFHQGAAGATVSDSATILNSSDKELTFQVFATDAANTPSGGAFALLPAETKPKDVGTWIALAPQAAATVTVPPKGRADIPFTVKVPGDATPGDHVGGIVALNTAVEGVQKDGKVQVGVKRSVGARLYFRVPGPLTPGLSVEDVRVTRGAPLLPWVKDARATVSYALVNRGNVVVEPKVAVSARGLFGRRVLDRPARQPKLVLLPGQRVELTEPWPDSPQLDWVSVTVSAGAAAYPDLSSESATDFLAVPWTAAGAVLVLAGAGTAVLVLRRRRRSDPPRPEPARDLARTR
>NZ_CP024985.1|WP_030229540.1|5417060_5418353_-|hypothetical-protein
MSTTFRRRVLAGAGALSLALTGGVVALTGTAQAATKTTSVPVKCVAPAPQPGANGNQDYTITLPDTAKAGQSVPITIDPGETPVVPMFTIDTVNTIKAKLLVGGVAQTVTSAAVPSHQEAGKKADPPAFSGNITIPDGTEGTTVQITIDQVVTDADLGGTVYTTTCTPEPRPSASVGSVAVEALPKDPVTTRLAPNSGKAGTAVTATGANFPAGPVTCSALLAGAATGDTGTGTADASGAATCNITVTKKADAIKIDGSVPPTKPFVFVEEQAGVQNPVDIEVLPGPLALGPKDGQPAVSFGSVTINGKAQSVFGAFNAATVQDFRGGSLGWDVTATRTPFLNQATGHSMAKAQIGIQPSCTVTNPDSPSTCTAGVPGAITDTPMKVASQAAGGDELTGGEFAVGGAAMLQLPPFMFADTYQSVVTFSIA
>NZ_CP024985.1|WP_030229542.1|5418571_5419942_-|S8-family-peptidase
MRPVGAPSARRRRGGPSIGGMTAMTALLPAAALLATATVLPPHTADAARATDAPTAPYVVVLKDTSSRAPARALAAEAAEAGDRVSAVYDAALDGFAVRTTAARAAELAADPRVASVEPDGLYRISEDPTPPPPSAPPAPTAAPAPAPAVAGVAVQRSAPWPLDRIDQRELPLDGSYAYASQGRGVTVYVVDTGINTLHQEFGGRAHAGYNAVFLEGAADCNGHGTHVAATVGGATYGVAKGVSLVGVKVADCRGDGRLSAILRGLDWMVKDAVRNATKGPYVANMSMGGTRSHAMDAAVIRAVASGITFTVAAGNEGKDACAGSPSGVPQALTVGATDAADRRPAFSNHGPCVDISAPGVSVVSAWKGSATALARASGTSMAAPHVAGAAALILAAPGDATPGTSATPGTATGAPGLHPSPEQVRQALVRSAVPDRITNLPAGTTNLLLHVPTDR
>NZ_CP024985.1|WP_030229544.1|5419971_5420382_-|GNAT-family-N-acetyltransferase
MDIRRARSCAELVAAEGLFDGPAREEWARRFLDAPGHLMLIAYVGDVPVGMVSGVEMTHPDKGAEMCLYELSVDEAHRRRGIGRALALALADEARARGCYGMWVGVDTDNGPALATYESAGAEDEGVFTMRGWALG
>NZ_CP024985.1|WP_037687114.1|5420479_5421181_-|4'-phosphopantetheinyl-transferase-superfamily-protein
MIEYVNQLGEDIPRTGALPVGGTVTVWSLDTTREVVGGHEVAGAVALLDASERDRLSRLLRAGDRRSYLASHVGLRVLLGGYLGLAPEKVALVREDCPCCGGPHGRPAVAGGAVHFSLSHSDDMAYFAFAGVPVGVDIEGLPGAGAVDDVLGTLHPAETAELVGLPVADRPAALARVWSRKEAYLKATGTGLALGLADPYVGSAATPAPVAGWTLSDLPAPPAFAAALALRST
>NZ_CP024985.1|WP_030229547.1|5421262_5422039_+|alpha/beta-hydrolase
MLSAVVTPEGDRIRWVELAGQGPARVYLHGLGATSPAYFAAVAAHPLLAGRRSLLVDMLGHGHSDRPEAFTYTLEAHADAVARALSEAGVEGAELIGHSMGGAVAIVLAARHPRLMSRLVLVDANLDPVPAVPRAPGSSGIASYTEEEFLAGGWSEVRDRVGAHWWSTMRLAGRTALHRSAVHLAAGTTPTMRELLLDLKLPRTFLYPQADGSLPGAEALEAAGVAVVAVPDCGHNIMLDNPEAFVRATAAALAPATP
>NZ_CP024985.1|WP_030229549.1|5422088_5422625_-|hypothetical-protein
MNRRPLVIAAALAGAFAIAALALPNLPPNPVTNTLNDRFFKEKGRHFATAADAPTRGDLAFVLPSWIPKDATDVRVRVRTTGEARLIRFTLGKTPLDGPQCAVSAPKKAGGPHLNARWWPGDTRSEERPECRDRYQYQVAVRGRKVYAWTDGTPSPGARIPDGRPSLAPASAVPTGRR
>NZ_CP024985.1|WP_030229551.1|5422893_5423367_+|hypothetical-protein
MRLRLAPLLAATAAAGLLALATPASAAPADKPQVLSTWTQTSASSYNAWLAARGSQGNWSAYGFDWSTDYCSSSPDNPFGFPFQTACARHDFGYRNYKAAGSFPANKSRLDDALYADLKRVCSQYSGVKKGSCDSTAWTYYQAVKAFGVSPQDAPAA

Crispr_ID: NZ_CP024985_22

• CRISPR_ID: NZ_CP024985_22
• CRISPR_location: 5440571-5440669
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP024985_22

Consensus_repeat	Method
CCTGCGGGGCGGCGGCGTACGGGTCCCCGG	CRISPRCasFinder

spacers of NZ_CP024985_22

>22.1|5440601|39|NZ_CP024985|CRISPRCasFinder
GCGCGGCCGGGCCCTGCGGTTCCCCGGCCGCGGCCGGGT

CRISPR arrays and Neighbor proteins around NZ_CP024985_22

CRISPR arrays

The CRISPR arrays of NZ_CP024985_22

>merge|NZ_CP024985|22|5440571-5440669|CRISPRCasFinder
CCTGCGGGGCGGCGGCGTACGGGTCCCCGGGCGCGGCCGGGCCCTGCGGTTCCCCGGCCGCGGCCGGGTCCTGCGGGGCGGCGGCGTACGGTTCCCCGG

>NZ_CP024985|22|23|5440571-5440669|CRISPRCasFinder
CCTGCGGGGCGGCGGCGTACGGGTCCCCGG	GCGCGGCCGGGCCCTGCGGTTCCCCGGCCGCGGCCGGGT
CCTGCGGGGCGGCGGCGTACGGTTCCCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_051840788.1|5431907_5432492_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229582.1|5452166_5453504_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270451
NZ_CP024985.1|WP_030229558.1|5431075_5431786_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229568.1|5438247_5439567_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238119
NZ_CP024985.1|WP_030229574.1|5443966_5445241_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229581.1|5451220_5452162_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP024985.1|WP_030229563.1|5434793_5435513_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229562.1|5434341_5434797_+|acyl-CoA-thioesterase	unknown	unknown	gnl|CDD|223894
NZ_CP024985.1|WP_030229579.1|5449033_5450299_-|6-phospho-beta-glucosidase	unknown	unknown	gnl|CDD|133432
NZ_CP024985.1|WP_078950291.1|5447990_5449043_-|ATPase	unknown	unknown	gnl|CDD|225518
NZ_CP024985.1|WP_078950302.1|5439605_5440529_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NZ_CP024985.1|WP_051840809.1|5446378_5447662_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030229567.1|5437117_5438203_-|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|238017
NZ_CP024985.1|WP_030229565.1|5435552_5435957_-|globin	unknown	unknown	gnl|CDD|381280
NZ_CP024985.1|WP_100661306.1|5436152_5437121_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|275041
NZ_CP024985.1|WP_078950290.1|5445296_5446373_-|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_CP024985.1|WP_030229580.1|5450304_5451213_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP024985.1|WP_167456831.1|5441138_5443913_-|protein-kinase	unknown	unknown	gnl|CDD|319004
NZ_CP024985.1|WP_030229584.1|5453586_5454840_-|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NZ_CP024985.1|WP_078950289.1|5432667_5434332_+|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030229582.1|5452166_5453504_-|extracellular-solute-binding-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.21046e-66
NZ_CP024985.1|WP_030229580.1|5450304_5451213_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.84565e-86
NZ_CP024985.1|WP_030229568.1|5438247_5439567_-|VWA-domain-containing-protein	gnl|CDD|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	2.39331e-16
NZ_CP024985.1|WP_030229581.1|5451220_5452162_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	9.75491e-69
NZ_CP024985.1|WP_078950290.1|5445296_5446373_-|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.1663e-85
NZ_CP024985.1|WP_030229562.1|5434341_5434797_+|acyl-CoA-thioesterase	gnl|CDD|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	2.02688e-28
NZ_CP024985.1|WP_030229579.1|5449033_5450299_-|6-phospho-beta-glucosidase	gnl|CDD|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP024985.1|WP_078950291.1|5447990_5449043_-|ATPase	gnl|CDD|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	5.01801e-19
NZ_CP024985.1|WP_078950302.1|5439605_5440529_-|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	8.22214e-36
NZ_CP024985.1|WP_030229567.1|5437117_5438203_-|FHA-domain-containing-protein	gnl|CDD|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	1.91983e-21
NZ_CP024985.1|WP_030229565.1|5435552_5435957_-|globin	gnl|CDD|381280	cd14771, TrHb2_Mt-trHbO-like_O, Truncated hemoglobins, group 2 (O); Mycobacterium tuberculosis hemoglobin O like. The M- and S families exhibit the canonical secondary structure of hemoglobins, a 3-over-3 alpha-helical sandwich structure (3/3 Mb-fold), built by eight alpha-helical segments. Truncated hemoglobins (TrHbs, 2/2Hb, or 2/2 globins) or the T family globins adopt a 2-on-2 alpha-helical sandwich structure, resulting from extensive and complex modifications of the canonical 3-on-3 alpha-helical sandwich that are distributed throughout the whole protein molecule. TrHbs are classified into three main groups based on their structural properties and named after Mycobacterium sp. genes glbN, glbO, and glbP: TrHb1s (N), TrHb2s (O) and TrHb3s (P). This group includes a Mycobacterium tuberculosis TrHb2, Mt-trHbO, encoded by the Mycobacterium tuberculosis glbO gene, which is expressed throughout the Mycobacterium growth phase. It also includes a TrHb2 from the thermophilic Thermobifida fusca ( Tf-trHb) which has a high thermostability and at the optimal growth temperature for Thermobifida fusca (between 55 and 60 degrees C ), it is capable of efficient O2 binding and release. Tf-trHb shares a relatively slow rate of oxygen binding with Mt-trHbO.	8.46258e-66
NZ_CP024985.1|WP_100661306.1|5436152_5437121_+|methyltransferase-domain-containing-protein	gnl|CDD|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	4.75196e-81
NZ_CP024985.1|WP_167456831.1|5441138_5443913_-|protein-kinase	gnl|CDD|319004	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat. This domain is found at the C-terminus of protein kinase G and contains a tetratricopeptide repeat (TPR).	8.06867e-90
NZ_CP024985.1|WP_030229584.1|5453586_5454840_-|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.41258e-35
NZ_CP024985.1|WP_078950289.1|5432667_5434332_+|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0

Protein sequences

>NZ_CP024985.1|WP_078950302.1|5439605_5440529_-|serine/threonine-protein-phosphatase
MDTDGYCEHCGHAQPRERDHLEEELCSVAAVSDRGLRHHRNEDSFAVAATALPDGSAATVAIVCDGVSSASRPDEASAAAAGAANEALLDALPRGAHPSEAMHGAILAAAAAVSALAPQTPGAQNAPACTLVGAVVSGGVLTIGWVGDSRAYWVPDDRAALPRRLTEDDSWAAQMVAAGLMGEAEAYADVRAHAITGWLGADAYDLDPHTASFRPDHPGVVVVCTDGLWNYAESATDMAQILPADAAARPLHSAQVLVGHALDGGGHDNITVAVVPFAAEPEAVREPAAEAEPEAPVRAETEPRAEA
>NZ_CP024985.1|WP_030229568.1|5438247_5439567_-|VWA-domain-containing-protein
MANFAKPSAPRFSVEVYQNEFLPAGGRDVHAIVTVTSTGGATATRALGRDAAVVIMVDCSGSMEYPPDKMRGAREATAAAIDTLRDGTAFAVIAGTHVAKEVYPGRGGLATAGPDTRAQAKEALRGLGAGGGTAIGTWLRLADGLLRQSTATIRHGVLLTDGRNEHEEPAVLRATLDSCAGRFTCDARGVGTDWEVKEVTGIASALLGSADIVADPAHLAEDFTRMMENAMGKEVADVALRLWTPVGAEVRYVKQVSPSVQDLTDRRTAAGPRAGDYPTGSWGDESREYHVCVRVPGASVGQEMLAARASLVLPGPPGGPQPPLAQGLVRAVWTDDLAASTAISPQVAHYTGQAELAQAIQQGLEARKMGDVDGATAKLGRAVQLASVSGNADTARLLAKVVDVVDAVAGTVRLKAKVADADEMTLETRSTQTVRVKKT
>NZ_CP024985.1|WP_030229567.1|5437117_5438203_-|FHA-domain-containing-protein
MPTCPNGHQSASDDWCEVCGHRMAAPTGTPAAPSYGYGYPPTSGEPTAQAELCPQCRTPREAMAPFCEECRYNFLTRSATPYAAAPDAGPNGAPNGTAGQGPGQASGAGMGTGAGTPPPPPPAPPQPVYSQDHFDYQGSRPSRVNRPAEPLQGEDDWLLPPPASERQPQPAQPQPVHQEYRQQPPPPPEYPQQPAGQPAPPPQHQPHEYQPQQPQQAHQPFPPQSGTGSWTATIGPDRSYFMAMMQRSGPEAAGLNLPAYSPEQHLPLSGGQITIGRRRASTGESPDVDLSVPPEDPGVSHQHAVLVQQPDGSWAVVDQNSTNGTTINGGEEAIQPYVPVPLADGDRVHVGAWTTITVRRG
>NZ_CP024985.1|WP_100661306.1|5436152_5437121_+|methyltransferase-domain-containing-protein
MRATAHAAQVRELTAVGALEDPAWRAAFAAVPRHLFVPYFWTGRGAGHERLWCEDPDPVRRARWLRGVYTDAPLATRLRDGELVSSSSQPSLMAKMLQSLEVRDGDDVLEIGAGTGYNAALLCHRLGEEHVTTVDLDEEITEAARAHLALLGYRPTVVTGDGARGCPARAPFDRILVTCTLPLIPHAWLGQCRPGARILAPLSTGLIALTVRDADFAEGRFLHTSAYFVPLRGATASPLPAGTTGPLHGVPYELVENERFQFLLILTAGVLHPREALDLWRGEGRPSRERFGVTVTAEGQWSWLDDPQGPYVWPLGEAVGQR
>NZ_CP024985.1|WP_030229565.1|5435552_5435957_-|globin
MNDDPQSTVQETTFYEQVGGEETFRRLVHRFYEGVAGDPLLRPMYPEEDLGPAEERFVLFLMQYWGGPTTYSQHRGHPRLRMRHAPFQVDAAAHDAWLGHMRVAVDELGLAPAHEAQLWRYLTYAAASMINTAG
>NZ_CP024985.1|WP_030229563.1|5434793_5435513_+|hypothetical-protein
MNEQLHFADSGEAADLAAFLGRLVHYDRAAAVRLQARAGGGALAVFGRPPSFDVLAVRTARLAAPLATPLDVTVSAGELLEAVDETGAGVLVPGPVTGPPWAGVLPPHGGWQPVPGLPAPEAVRAAVAAAVAEFRARDEALPPQHRTRSERDRIGREIWSRTLGDTDLPLRAVHAAQSLGFLRPVRATVPPATTPAGAPAPVALFASGGWLRLATPYGSVAMRRPGRTGGLGALQVRPV
>NZ_CP024985.1|WP_030229562.1|5434341_5434797_+|acyl-CoA-thioesterase
MARHHYRCPLRWADMDAFGHVNNVVFLRYLEEARIDFMFRLAPGEGSDSFTGGSVVARHEIDYKLPLVHRHEPVLIESWVTRIGAASLTIRYEVKDEATADAPETVYVRAETVVVPYNLAEGRPRRITAEERHFLEQYLDTPAAAEGRLAA
>NZ_CP024985.1|WP_078950289.1|5432667_5434332_+|energy-dependent-translational-throttle-protein-EttA
MAEYIYTMRKTRKAHGDKVILDDVFLNFLPGAKIGVVGPNGAGKSTVLKIMAGIEQPSNGDAFLSPGYSVGILMQEPKLDESKTVLENVEDGVGEIKTKLNRFNAIAEEMATNYTDELMAEMGKLQDDLDHANAWDLDAQLEQAMDALGCPPGDWPVTNLSGGEKRRVALCKLLLEAPDLLLLDEPTNHLDAESVNWLEQHLAQYKGAVVAVTHDRYFLDNVAEWILELDRGRAHPYEGNYSTYLEKKAERLKVEGKKDEKRAKRLKEELEWVRSNAKGRQAKSKARLARYEEMAAEADKMRKLDFEEIQIPPGPRLGSIVVEVNNLSKAFGDKVLIDDLSFTLPRNGIVGIIGPNGAGKTTLFKMIQGLETPDSGEIKVGETVKISYVDQGRANIDPKKSLWAVVSDELDYINVGQVEMPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLLLLDEPTNDLDVETLGSLENALLEFPGAAVVVSHDRWFLDRVATHILAYEGDSKWFWFEGNFESYEKNKVERLGPDATRPHRATYKKLTRG
>NZ_CP024985.1|WP_051840788.1|5431907_5432492_-|hypothetical-protein
MESTYIGLAVAVVGVAGTLMASVLSPRLLARIQSEQFTREQRAAEAQWLREQQVAGLARRREAYANVNASFRRYRTHLLNFLWTVHKGAVTEAAREVIEEARRDHHSVFAAAQIVASARVLAELNTMTRTLSETYRRIMCLEEGDPDPDGSFEELKGDFTRLWDQWEEMLGAMRADLGVEESGSGRADAASSAS
>NZ_CP024985.1|WP_030229558.1|5431075_5431786_-|hypothetical-protein
MDNALLALASAIVAVTGTLLAPVLSQRITGRVQADQFDRQERLARAQWQRDRRVAEREKRRDCYVHANAGYRRYRVELMNHLWAVHRDEVTDEGRAALQEARHAMHSAFAEAQMIASDAVMAELDVLTRELAGAYARTMRLERGNPLPGWGFDEVLAALLDLGDAWVRARAVMRADLGVEPGPVAADDAAAGEGRGGEGPDGDGPDAARPDGDGPCGPGGRPGEAGAPSGGGQRGR
>NZ_CP024985.1|WP_167456831.1|5441138_5443913_-|protein-kinase
MGGGEVYCDTCGLAPVGSVAAGAEELVSPPTGMTSAARHGDSRGSAGSRGSGRSSASARSSRSSRSSSSRRSVSGRLSRSLPGAASTRSVSVRSSGSAAPSSGRSRLGAGLVTMPEVPRPDPSAAVLENPEVPERKRFCSRSDCGAPVGRARGDRPGRTEGFCTKCGHPYSFVPKLRAGDVVHGQYEVAGCLAHGGLGWVYLAVDRAVSNRWVVLKGLLDTGDQDAMEAAISERRFLAEIEHSNIVRIYNFVEHLDQRTGSLDGYIVMEYVGGKSLKEIANERRRPDGRRDPLPVEQACAYGIEALEALGHLHSRNLLYCDFKVDNAIQQQDQLKLIDMGAVRRMDDDESAIYGTVGYQAPEVAELGPSVASDLYTVARTLAVLTFDFQGYTNVFVDSLPDPEHIEVFGRYESFYRLLVRATDPDPGRRFASAQEMADQLTGVLREVVALQTGRPRPQPSTLFGPELRVPDTRLYADVAGAEVSRLGVREVPRGVWGRRRRSVAPVPGPAPLPPPAPAGEPGAAGAGVPEPSGAGVSVPAPVTGAGAGAGPGAGSGAGSVPALGTSATHIAGAGVPAPRRGSAAPGPDPVPAPAPLPVLAAVPPGAGAPVAAPAATGPAPLDAHDTALALPVPLVDPADPNAGFLAGLLASAPADLLGALGSAPADSAELRLRELRARLELGELAVAGEALTELEERHPDDWRVVWARGIASLATGDDEIAALSFDAIYDAFPGEPAPKLALGLCAEVLGQLDNAAEYYRLVWITDPGFVSAAFGLARVQLAAGDREAAVLTLESVPEASIHYTAARVAAVRARLRDRSPQEALLADLLAASGQVEALRRFGLDPERYERLATEVLGSALDWVLSGSRGADPGRTSLLGSQLDERGLRFGLERSYRVLARLAQRGEERIELVERANRFRPRTWV
>NZ_CP024985.1|WP_030229574.1|5443966_5445241_-|hypothetical-protein
MDRDEVDRALARLGAEHEAVETSLLALQDHAGRRLLEGAALSGVTEERWAAADAAVTRLWTYFDAYSGALAAAREIRERRRWPTREDLAELTERLRGPGVVIAGAGAGGSALAERFSLAELVARMNELYAGSLDVVVAADAVWSALPARIDLLGAELHRTRALAHSVGVRPGEHPSGDDLEEITAELAELRARVIADPLGFWIPAAGSSAPGGGRPDTGRYDRAARALDDVRREVEAVLTVRQDAEARLIGVRDVLSRADRTLAEARTARVEVLAKIAASEVPAVSGPPTALQEELAAAAEYRRRSQWHRLSPLLDSLEDRSDEELTRARESLTAVTAPLAVRAELRGRLDAYKAKVARHGMAEDPLLIERYDAARRMLWSAPCDLRAAEQAVLRYQRATAETLVPRQPLPEDHRPAGPEEEDA
>NZ_CP024985.1|WP_078950290.1|5445296_5446373_-|glutamate-ABC-transporter-substrate-binding-protein
MRIRRTRAGHQAASAPAAATAGAPAAAEAARPRRAVRRLRGWGGVSAMAAACAVTAAAVLLPLARTSPGTAHRNAVQEPATMAAAPFAPADTCQDPEASLAPSGMDGPTIERIRKAGKLVAGVDQNSFKWGYRNPDGHLDGFDIDLVKAIAKDILGREDAVIYRAIPTSQRIPALQEGRVDVVVRTMTINCKRLEDVAFSTAYFEAGQQVLAPKGSHITGYDASLQGRRICTAAGSTAEAALKAKSYGAAAVSVPNQLDCLVRLQLGEVDGIITDNALAAGQAAQDPSVQLVGAPFTREFYGVAMNKDASDLVRRVNKVLENYRAGGEQSPWAVSYRKHFENVLPGQAQPPAPKYRNG
>NZ_CP024985.1|WP_051840809.1|5446378_5447662_-|hypothetical-protein
MRAAATTEPGRLRIIGAALAALVVLFGAVAVWEVSGRVTAADDVVGRSQPLSADAASIYRSLADADTASSSGFLAGAQEPRDVRLRYEKDIANASRLLVSAAANTGAGGDSRKEIALLGEQLPRYTGLIEQARATNRQGLPLGGAYLRYANEQMSTVLLPAAQRLYEAETGRLYTDYDEARAWPLASTGAGVLALAALVWAQRRNYLRTHRVFNHGLLAATAAAAIVLLWLTVGQTFARSGLSEARTGGQESLKVLNDARIASLQARANENLTLIARGAVLAADKKSDKYDVDYEKNMKQLDEGLARALRLADDTSGREPVSQAVAGVAQWKQRHAAARESDMKGDYELALPQVIGDERHPDSSGASFDTVDASLERAVAHEQNQFTRAARGGLGALGGLVTGSAALAAVGAAAALLGIGRRLSEYR
>NZ_CP024985.1|WP_078950291.1|5447990_5449043_-|ATPase
MGVTGVPGTTGTTGTTGTARASGPAAAVLAVDAGNSKTDVALIGADGTVLGTGRSGGFQPPRIGIEAAVDVLGQAVDEATAAAGLRPGAPCAELVSACLANADLPVEERQLTAAVGARGWGTRTEVRNDTFAILRAGLSGTDLPRGVAVVCGAGINCVGMLPDGRTARFPALGVISGDWGGGGGLAEDAMWWAARAEDGRGGPTLLAQAMPAHFGLASMAALIEALHLGAVARGRMHELVPVLFAVAAAGDPVASAIVERQAGEVVALAAVALERLDLLREEVPVLLGGSVLAAGHPQLNDRIAELLAARAPLARLSVVTAPPVLGAALLGLDALAAPPDSHAKLRAHFG
>NZ_CP024985.1|WP_030229579.1|5449033_5450299_-|6-phospho-beta-glucosidase
MKLAVVGGGSTYTPELIDGFARMRDTLPVAELVLIDPAAERLELIGGLARRILARQGHPGTVTTTSDLDAGVAGADAVLLQLRVGGQAARLQDETWPLECGCVGQETTGAGGLAKALRTVPVVLDIAERVRRSAPDAWIIDFTNPVGIVTRALLGAGHKAVGLCNVAIGLQRKFAALLDVAPAEVHLDHVGLNHLTWETGVRLGGPDGTDVLPRLLAGHGDAVAADLRLPRALLNRLGVVPSYYLRYFYAHDEVVRELGEKPSRAAEVAAMEKELLALYGDPALDEKPALLAKRGGAFYSEAAVDLAAALLGGGGPSVQVVNTRNDGTLPFLPDDAVIEVQARVDGSGPVPLPVPRLDPLFAGLTAHVSAYEDLALDAALRGGRERVSKALLAHPLVGQYDLAEGLTDRLLAHNKEHLPWA
>NZ_CP024985.1|WP_030229580.1|5450304_5451213_-|carbohydrate-ABC-transporter-permease
MTDTNPTDERPRTRPPAGGPAPAARPRTRKAVLHWVAVHSLGVAAALFFVLPFVFLFLTSLMSDHQALTRDLWPRTWEWGNYAKVWHTPGFLTWWRNTLLYAGLGTLLTVVSSVPVAYALAKFRFRGRRLALLLVIAMMMLPPQVVVIPMYLFWAKQLDLSGTLWPLIVPMAFGDAFSIFLLRQFLLTIPDEYLDAARVDGCGELRTLLRVVLPMARPGIAAVALFQFFYAWNDYFGPQIYASDNPAAWTLSYGLESFKGAHHTNWNLTMAATVLVMAPVIVLFFLAQKAFVEGVTLTGVKG
>NZ_CP024985.1|WP_030229581.1|5451220_5452162_-|sugar-ABC-transporter-permease
MAPNTARAKRRRAALRTAAFLSPWLIGFAVFFAYPLLSTVYFSFTRYDGFRPPVLNGLANWSYVFTDYPLFWPAMRNTLWLVVVMVSCRVVFGLGIGLLITKIKTGAGIFRTLFYLPYLAPPVAATLAFVFLLNPGTGPANTLLDGMGLPTPGWFTDAAWSKPALTALALWGVGDLMVIFMAALLDVPKEQYEAAELDGAGARARFRHITLPNISPIVLFAVVTGVIQAMQYYTQPLVAGKVAAGVIGGSGQQFEPGYPDKSTLTLPQLVYNVGFQRSDYGAACVVALVLFALSMAFTALLMRRRGGLIGAGD
>NZ_CP024985.1|WP_030229582.1|5452166_5453504_-|extracellular-solute-binding-protein
MPRTGRRPITAATLLAALCVLATSCTGQSAGTASDDPKADVTLKFWHGWNTPAEVKAIEENIARFEKAHPNIKVEVTGDITDDKVNQALRAGGDKAPDVVSSFSTDSVGKFCNSGALADLNPFLLKSGIDKAKVFPKTLLEYTRFKDDQCTLPLLHDAYGLVYNKTAFTAAGITEPPKTWSQFVADAQALTKSNGDSYDQLGVMPTFHGYETTPMRLVAQWSPTYFAADGSSNLAKDPAFAKMLTAQKDLVAKLGGFEKLERYRAGFGDEWSSAHPFNKGQVVMQIDGEWRAAMAEEAGVGFEVATAPLPVPDDQVDDYGKGYLSGTIMGISSTSRKQNAAWELVKYMTTDTGAVVAFANSIHNVPSTLAALESPDLKVTPALKTFMDIARHPKSNTTPAQPDGGTYQLTFQDFAYRFEKGDVPDLQAGLAATDRQIDTDIAKAK
>NZ_CP024985.1|WP_030229584.1|5453586_5454840_-|ROK-family-transcriptional-regulator
MPAATPGTPSLLRAMNDRAALELLLTHGPLSRTRIGHLTGLSKPTASQLLARLEAAGLVVATGTDGGRPGPNAQLYALNARVAHVGGLDVTPEGVVAAVADLSGTVVGGFELPYAEGAEAVAQVTAALDGAVAAAGLHRDDLHRLVIATPGAFDPQTGRLRYASHLPGWHSPTLLDELAAALPMPVEYENDVNLAAVAEQRLGAARGHEDFVLLWNEEGLGAALVLGGRLHRGWTGGAGEVGFLPVPGHPLVRQVTRANSGGYQELAGAQVLPRLAREHGVEVPAAPGTDTGTGALPPGSAAAPPGPQVAAAVALLRRAAAEPEGPHLDFLRSYATVLATGLASLVAVLDPELVVLSGAVISAGGDPLRTLLQDELAEIAPSRPRLVAGEVHERPVLRGALESALAAAREEVFDTSR

Crispr_ID: NZ_CP024985_23

• CRISPR_ID: NZ_CP024985_23
• CRISPR_location: 5646293-5646469
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP024985_23

Consensus_repeat	Method
CCGAGTCCCAGCCGATGA	CRT

spacers of NZ_CP024985_23

>23.1|5646311|18|NZ_CP024985|CRT
CCTTCTTGTCCGCGGGGG
>23.2|5646347|30|NZ_CP024985|CRT
CCTGCGGGGTGGCGGGGCCCGCGGCGCGCA
>23.3|5646395|18|NZ_CP024985|CRT
CCGCCTTGCCGGCCGGAG
>23.4|5646431|21|NZ_CP024985|CRT
CGGCCGGAGCCGCTGCGCGGA

CRISPR arrays and Neighbor proteins around NZ_CP024985_23

CRISPR arrays

The CRISPR arrays of NZ_CP024985_23

>merge|NZ_CP024985|23|5646293-5646469|CRT
GTCAGTCCCAGCCGATGACCTTCTTGTCCGCGGGGGCCGAGTCCCAGCCGATGACCTGCGGGGTGGCGGGGCCCGCGGCGCGCACCGAGTCCCAGCCGATGACCGCCTTGCCGGCCGGAGCCGAGTCCCAGCCGATGACGGCCGGAGCCGCTGCGCGGACCGAGTCCCAGCCGATGA

>NZ_CP024985|23|5|5646293-5646469|CRT
GTCAGTCCCAGCCGATGA	CCTTCTTGTCCGCGGGGG
CCGAGTCCCAGCCGATGA	CCTGCGGGGTGGCGGGGCCCGCGGCGCGCA
CCGAGTCCCAGCCGATGA	CCGCCTTGCCGGCCGGAG
CCGAGTCCCAGCCGATGA	CGGCCGGAGCCGCTGCGCGGA
CCGAGTCCCAGCCGATGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030227087.1|5641943_5643677_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP024985.1|WP_030227072.1|5633855_5634626_+|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|187600
NZ_CP024985.1|WP_030227102.1|5650778_5651849_+|esterase-like-activity-of-phytase-family-protein	unknown	unknown	gnl|CDD|379191
NZ_CP024985.1|WP_051840473.1|5655035_5656145_+|cation-transporter	unknown	unknown	gnl|CDD|376562
NZ_CP024985.1|WP_158740537.1|5634696_5635056_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030227107.1|5652276_5653629_-|acetyl-CoA-carboxylase	unknown	unknown	gnl|CDD|223848
NZ_CP024985.1|WP_030227092.1|5645348_5645651_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_051840496.1|5638019_5638613_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_051840469.1|5651889_5652246_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030227075.1|5635107_5637204_+|molybdopterin-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|239155
NZ_CP024985.1|WP_158740539.1|5647904_5649119_-|glutamate--cysteine-ligase	unknown	unknown	gnl|CDD|237408
NZ_CP024985.1|WP_030227085.1|5640024_5641947_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP024985.1|WP_051840499.1|5638881_5639949_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|235640
NZ_CP024985.1|WP_030227120.1|5656141_5657707_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|225113
NZ_CP024985.1|WP_030227100.1|5649333_5650587_+|MFS-transporter	unknown	unknown	gnl|CDD|236700
NZ_CP024985.1|WP_030227111.1|5654400_5654841_+|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_CP024985.1|WP_030227078.1|5637333_5638023_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030227090.1|5643851_5645297_-|sugar-kinase	unknown	unknown	gnl|CDD|198375
NZ_CP024985.1|WP_030227095.1|5646832_5647819_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_CP024985.1|WP_051840471.1|5653646_5654330_-|LysE-family-transporter	unknown	unknown	gnl|CDD|224199

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030227087.1|5641943_5643677_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.50009e-161
NZ_CP024985.1|WP_030227072.1|5633855_5634626_+|glucose-1-dehydrogenase	gnl|CDD|187600	cd05341, 3beta-17beta-HSD_like_SDR_c, 3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. This subgroup includes members identified as 3beta17beta hydroxysteroid dehydrogenase, 20beta hydroxysteroid dehydrogenase, and R-alcohol dehydrogenase. These proteins exhibit the canonical active site tetrad and glycine rich NAD(P)-binding motif of the classical SDRs. 17beta-dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens, and include members of the SDR family. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	3.09443e-107
NZ_CP024985.1|WP_030227102.1|5650778_5651849_+|esterase-like-activity-of-phytase-family-protein	gnl|CDD|379191	pfam13449, Phytase-like, Esterase-like activity of phytase. This is a repeated domain that carries several highly conserved Glu and Asp residues indicating the likelihood that the domain incorporates the enzymic activity of the PLC-like phospho-diesterase part of the proteins.	2.9592e-58
NZ_CP024985.1|WP_051840499.1|5638881_5639949_+|RNA-polymerase-sigma-factor	gnl|CDD|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	1.37748e-161
NZ_CP024985.1|WP_158740539.1|5647904_5649119_-|glutamate--cysteine-ligase	gnl|CDD|237408	PRK13517, PRK13517, glutamate--cysteine ligase.	1.88469e-116
NZ_CP024985.1|WP_051840473.1|5655035_5656145_+|cation-transporter	gnl|CDD|376562	pfam01544, CorA, CorA-like Mg2+ transporter protein. The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Archaea. There are also eukaryotic relatives of this protein. The family includes the MRS2 protein from yeast that is thought to be an RNA splicing protein. However its membership of this family suggests that its effect on splicing is due to altered magnesium levels in the cell.	4.35486e-47
NZ_CP024985.1|WP_030227075.1|5635107_5637204_+|molybdopterin-oxidoreductase-family-protein	gnl|CDD|239155	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol oxidation via a membrane-anchored tetraheme cytochrome. Members of the MopB_Nitrate-R-NapA CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_CP024985.1|WP_030227107.1|5652276_5653629_-|acetyl-CoA-carboxylase	gnl|CDD|223848	COG0777, AccD, Acetyl-CoA carboxylase beta subunit [Lipid metabolism].	6.34011e-50
NZ_CP024985.1|WP_030227085.1|5640024_5641947_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP024985.1|WP_030227100.1|5649333_5650587_+|MFS-transporter	gnl|CDD|236700	PRK10489, PRK10489, enterobactin transporter EntS.	6.73928e-69
NZ_CP024985.1|WP_030227120.1|5656141_5657707_-|GAF-domain-containing-protein	gnl|CDD|225113	COG2203, FhlA, FOG: GAF domain [Signal transduction mechanisms].	1.07412e-18
NZ_CP024985.1|WP_030227111.1|5654400_5654841_+|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	2.74677e-33
NZ_CP024985.1|WP_051840471.1|5653646_5654330_-|LysE-family-transporter	gnl|CDD|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	0.00100933
NZ_CP024985.1|WP_030227090.1|5643851_5645297_-|sugar-kinase	gnl|CDD|198375	cd07809, FGGY_D-XK_1, D-xylulose kinases, subgroup 1; members of the FGGY family of carbohydrate kinases. This subgroup is composed of D-xylulose kinases (XK, also known as xylulokinase; EC 2.7.1.17) from bacteria and eukaryota. They share high sequence similarity with Escherichia coli xylulokinase (EcXK), which catalyzes the rate-limiting step in the ATP-dependent phosphorylation of D-xylulose to produce D-xylulose 5-phosphate (X5P) and ADP. Some uncharacterized sequences are also included in this subfamily. EcXK exists as a dimer. Each monomer consists of two large domains separated by an open cleft that forms an active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. The presence of Mg2+ or Mn2+ might be required for catalytic activity. Members of this subgroup belong to the FGGY family of carbohydrate kinases.	4.22461e-115
NZ_CP024985.1|WP_030227095.1|5646832_5647819_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	8.54064e-11

Protein sequences

>NZ_CP024985.1|WP_030227092.1|5645348_5645651_-|hypothetical-protein
MRYKVTFVVGLALGYVLGTRAGRERYEELKKSVRGFVQNPAVRNAAETAGQSGRAFAGKAFAAVGEKVGDAVPDSLSERVRVLRGRGAAGSEDEWGTSNT
>NZ_CP024985.1|WP_030227090.1|5643851_5645297_-|sugar-kinase
MGIVAGLDSSSTFTRIVVCDTDTGAVLRQGYAPHPQPAGETVPHETDPQAWLLSLGEAAGGGLLEGVQAIGVSAQQHGVLPLDAQGALVRPALVGNDKRGQVAAADLVEALGGRQAWVAAVGSVPHSAQPVTKLAWLARTEPEAARRVAVVMSPHDWLVWQLLGRPARRTTDRAGASGTGYWSAATGSYRPDLVELALGHQALLPEVLGPADAAGTTPEGLLISAGTGETTAAVLGLGLGPGDAVVSLGASGSVMAVHHEALMEPGGLITSLADAGGMHLPVVNTSNAVRALRGTAELLGTDLEGLSALALKSTPGAHGLVLLPYLEGERTPNLPHTAGTLSGLRRDSMKPEHLARAAFEGMLCGLVDALDVLRHRGVPIRRVFLLGAAAELPAVQAAAPGLFGTQVVVPAPADYAALGAARQAAWALGVRQGTLAPHTPPVWPAAAAQVFEPGEELPAWQAVRQQYVTTREQLHPGAFQG
>NZ_CP024985.1|WP_030227087.1|5641943_5643677_-|ABC-transporter-ATP-binding-protein
MLIRLLRTHLGPYRKPITALVLLQLLQTSASLYLPTLNADIIDNGVVNGDTGYILRFGALMLGVSLVQLVCNVGAVYYGARTAAALGRDVRAAVFDRVQSFSARELGQFGAPSLITRTTNDVQQVQMLTLMTFTLMVSAPIMCVGGIAMALSLDVKLSGVLLAVVPVLGLAVGAIVFRTRPLFRQMQDRLDTVNRVLREQITGNRVIRAFVRDGYEEERFRTANSDLTGVSLASGKLLALMFPTVIVVVNISSVAVIWFGAMRVDSNGMEIGQLTAFLAYLMQIVMSVMMATFMFMMVPRAEVCAERIQEVLDTESSVVPPAEPVRKLLRRGQLELRGADFRYPGAEAPVLRGVDLVARPGETTAVIGSTGSGKSTLLGLVPRLFDATGGDVLVDGEDVRRLDPELLAKTVGMVPQKPYLFSGTVASNLRYGRPDATDEELWHALEVAQAKEFVSELQGGLDAPISQGGTNVSGGQRQRLAIARTLVQQPEIYLFDDSFSALDYATDAALRSALSRETEEATVVIVAQRVSTIRDADRIIVLDAGQVVGEGRHHELMAGNETYREIVLSQLTEAEAA
>NZ_CP024985.1|WP_030227085.1|5640024_5641947_-|ABC-transporter-ATP-binding-protein
MSGPGGRMMMGPAQRSMDFKGSGKRLLRQLAHDRAKLWGMVAAVFASVACAVVGPKILGEATDLVFAGIVGRQMPAGITKEQALEGLRAKGQDGMADMLSGTDFTPGEGIDFGAVGVVAIWALVVFTLAGLLMLVATRLSNHVMNGTVYRMREELQAKLSRLPLSYFDQQKRGEVLSRATNDIDNIGQTLQQTMGQLLNSLLTIVGVLTMMFWISPLLALVALVTVPVSIFVAAKIGKKSQPQFVAQWKSTGALNAHIEEMYSGHNLVKVFGRQKESAAVFAEQNEELYRASFKAQLVSGIMQPVMFFISNINYVLIAVVGGLRVASGTLSIGDVQAFIQYSRQFSMPLTQVASMANLVQSGVASAERVYELLDAQEQEPDAEVPERPEQLRGQVTLDKVAFRYELDKPLIENLSLSVEPGQTVAIVGPTGAGKTTLVNLLMRFYEVTGGEIALDGVDIAKMTREELRSGIGMVLQDTWLFGGTIAENIAYGASREVTRAEIEEAARAAHADRFVRTLPDGYDTVLDDEGAGVSAGEKQLITIARAFLSDPVILVLDEATSSVDTRTEVLIQKAMARLAHGRTSFVIAHRLSTIRDADVILVMENGSIVEQGSHEELLASDGAYARLYAAQFAQAVAEVD
>NZ_CP024985.1|WP_051840499.1|5638881_5639949_+|RNA-polymerase-sigma-factor
MDEAVDEAADPAARAAGDETAEDEGPDEGPEVLELIEHVPPPRTRGAESGGAGPSADLFRQYLREIGRIPLLTAAEEVDLARRVEAGLFAEEKLGGAADLDSQLAVDLDRLVVMGRMAKRRLIESNLRLVVSVAKRYVGRGLTMLDLVQEGNLGLIRAVEKFDYARGYKFSTYATWWIRQAMSRALADQARTIRVPVHVVELINRVVRVQRRMLQERGYEPTAEEVAVHLELTPERVLEVLRLAQEPVSLHAPVGEEDDVALGDLIEDGDAASPVESAAFFLLREHLEAVLSTLGERERKVVQLRYGLADGRPRTLEEIGRIFGVTRERIRQIESKTLNKLRDHAFADQLRGYLD
>NZ_CP024985.1|WP_051840496.1|5638019_5638613_-|hypothetical-protein
MSEMIDIMSSYGTYETHVTVLCPDAAELARLESWAGARELKVTHITPARGRARSRSMLTLPDRTGHERLVPQLRAAGFDPVRVKVETVPWSTEPAGPGGGYHEHHLRLLLPPGYDHGALEALVLPHGARLSWAACGGREQERYVTQRVRGSASRAAAACDTLIAELVAAGYEIDCELRELVLYDSDLSEDDRNGEGL
>NZ_CP024985.1|WP_030227078.1|5637333_5638023_+|hypothetical-protein
MVFRPQQPPASRALRVLPYRKPTRGRDYWVLDDVLPDVDAVRARCLAKEDWVQGAPHKPEPWPGLRAMPGLEPPELARVERLVRQATGARRIWPEDPEGAGTFNHNCVQVVGKDECEPRPHTDSRTLCRYAAVLYLSPGTPKDCGTSFYRQSLPGGVLGGNQVLAPHNNLVDALGTRFVPEDSFTEDVRVPHRYNRLLLYSANLIHSATGYWGTTLEDKRMTAVFFWMA
>NZ_CP024985.1|WP_030227075.1|5635107_5637204_+|molybdopterin-oxidoreductase-family-protein
MPTPEAAPAATTAATATHCPYCALQCGMLLRPTPDGTAVTVEERADFPVNRGALCGKGRTAPAVLSSRVRLTEPLVRTHAGRLVPATWEEALDAVAAGLARTARAHGRDAVGVFGGGGLTNEKAYALGKFARVALRTSQIDYNGRFCMSSAAAAHQRAFGLDRGLPFPLEDVPRTGCLILVGSNLAETMPPALRHLTELKANGGTLIVVDPRRTRTAEQADLHLAPRPGTDLALALGLLHLVVAEGRTDEEFIAARTTGWEQARAAAMAHWPELVERITGVPVPRLREAVGMFCDAPSAMVLTARGPEQQSKGTDTVGAWINLCLATGRAGRPLSGYGCLTGQGNGQGGREHGQKADQLPGYRRLTDPAARAHVAGVWGVDPETLPGPGRSAYELLDALGTDVRALLLMGSNPVVSAPRAAHVEERVRALDFLAVADVVLSETAALADVVLPVTQWAEETGTTTSLEGRVLLRRRALTPPSGVRSDLEVLHGLAARLGVEKGFPTDPEEVFEELRRASAGGPADYSGISYARVEAEQGVFWPCPEGSPGEPRLFLDRFATDDGRARFAPVSHREAAETPDADYPLLLTTGRVVAQYQSGAQTRRVPELNAAAPGPFVELHPRLAARLGVDDGTPLAVTSRRGRAVAPARVTDTIRADTVFMPFHWPGEGRANSLTNPALDPVSRMPEFKVCAVRVEPA
>NZ_CP024985.1|WP_158740537.1|5634696_5635056_+|hypothetical-protein
MEREAPLVREVLPALTAELVRLLEEEGERDLAVCAHDLRLVAVCGCGDDFCQSIRTGTHVPGTPYGPGVRSVHLLPERGMLNLDVLHGRIEYVEVLDRPEYRLPDPSPSPRDGAEGEHA
>NZ_CP024985.1|WP_030227072.1|5633855_5634626_+|glucose-1-dehydrogenase
MAVVDLSGKVVVITGGARGLGAAAAQAVVDGGGRVLITDVLEAEGAETAAKLGDAARFLRHDVTSEADWQAALEYAVAEFGRLDGLVNNAGISTGQFLEHESVEHFRRVVEINLVGVFIGIKTAIPLLRANGGGSVVNISSAAGLTGLALTAGYGASKWGVRGLSKIGAVELAEAGIRVNSVHPGMTLTPMTAPVGIQAGEGNYPGAPLGRVGVPEEIAAAVVFLLSDAAGYVTGAELAVDGGWTAGLTVKYLTGQ
>NZ_CP024985.1|WP_030227095.1|5646832_5647819_+|helix-turn-helix-transcriptional-regulator
MLEALGLDSHVERVYREMLADPTGGVAELGARLGLTEGQVRDGLDRLVDLDLLTPSRENAGGLRAVSPEAGLEQILRRQEEDLIRRQQELALSKAAAARAVAEFATLRPNTETDGAERLVGLDAIQSRLEVLAKGLSRECLAIMPGGAQSQASLDASRPLDEDALARKVAMRVVYQDSARNDPATLAYAQWTTERGGQVRTSPVLPPRLVIFDRATAVVPIDPENSRLGALCTTAPGIVASLVTLFEQTWGTAVPLGAAREQAGEDGITTAERELLKLLASGMTDEAAGKRLGVSLRTVRRQMSGLMERLDATSRFEAGLRAAQRGWL
>NZ_CP024985.1|WP_158740539.1|5647904_5649119_-|glutamate--cysteine-ligase
MIEPGNSTTSTSDTDRTGLTGATGAPGSAGRNLRVASGVTTPLTVGVEEEFLLVDAHTLRVVPAAPLVLATAAGLPQQVHAEGTRYQVELATPVAHSAAALRADLAGLRRTLAAAARAHGCRLLAAPSPVMAVEGPLHLTDDEPRQREQHRRFGALTDTLVSCGRHIHIGTLDVDTAVAVSNRVRPWLPTLIALAANSPFWGGRDTGHSSWRAMAWSGWPSAGPPPHFTSTAHFRRSVQTLLGSGAALDTKMVYWDLRPSGNWPTLEIRAPDMSPDIDTAVLQAELGRALVATALRELAEQRPDPPVRDDVLRLARWRAAHDGLEGFGLDPYTGAELPAADLAEALLDLVAPELAAAGDLDHAAKTLGGLLRDGSGAARQRAAFARRHDLTDVLRLLVEETENF
>NZ_CP024985.1|WP_030227100.1|5649333_5650587_+|MFS-transporter
MTGTASPPRPRRRIFADLTPLRTSAHYRRLWVGGTISWMGQAMTALAISLQVYEITGSSFSVGLVGLFSLVPLVAFGLYGGAIADTVDRRKLGLHSQIGLTVLSAGLAAAALLDYHRVWLLYTVVALQAVCGALNGPARSAMIPKLLPPEQLPAANALGSVTMTSGTMLGPVLGGLIVGWWGYQAAYLIDVVTFVAALYAMWRLPAMLPEGRKGRASVMDGLRFLGTTPNIRMTFFSDMAAMIFAQPKALFPAIAVLWYGGDAKTVGLLVAAPAVGALLGGLFSGWQGRVQRHGLAILLSVAMWGLAIAVFGLTRNLWLGLFFLALAGCADTISMVFRSTMMQTATPDGMRGRLQGVFIVVVAGGPRLGDFLAGTVADLTSPAVAVTGGGLACVLVLGLLAARWRAFARYDARSPQP
>NZ_CP024985.1|WP_030227102.1|5650778_5651849_+|esterase-like-activity-of-phytase-family-protein
MRLRTLVTTAVATAALTAALTPPALAAPRDGDRACSPRMTVRGFSDSLDKTLLDGKLVGGISALSLDRDGKVAAVSDRSALYTLDVARGDTPTARATRRLPLTDGAGAVVDSEGVVVDRDGTYLVTDETTPAIRRYDRTGGVLSTLPVPPAFRIAPQGRATVNQTFESLTLLPGGHTLVAGLEGQLAGDGKDARGRTLQRIQTWERRGNGEFVLGRQYAYPVDAGHGLVELAPTRDGRLIVLERGFTQQFAITARLYVADPLGAGDTLKVETLTEGRGLRPARKSPIGDFNDCPTLGAPSKLPQNHPLVDNIEGMVATEEDGSGRVRLLLASDDNEFPQQITRLYRVDVRLPDRRG
>NZ_CP024985.1|WP_051840469.1|5651889_5652246_-|hypothetical-protein
MAHDDTAVPKMAALFDAGPDKWGLRGDPHVWQALRDTLSGTDLPASADAVARLLRATFEELVEVDLSAEPAPHVYRERYAHGGMSGGTVHLDTWRRTLLPLLVERAERLLETRPGPGR
>NZ_CP024985.1|WP_030227107.1|5652276_5653629_-|acetyl-CoA-carboxylase
MTTTRLSARAAIAALADPGSFAELPAPQRESADDGPLGWTGYDASRARATARTGERESVVTGTARIGGREAALIAFEFGFLGGSLGERTGDRLEAAYAHARAHRLPLVSLIATGGSRMQEGMLALTQLQRVARQCVLTRAAGLPQIAVLRDPTTGGGWATLGAGADVVLALPGAQVGFAGSRVRPADADPAAYTAEGQYAAGHVDAVVPPGELPGVLGDWLRVLAAPRATAPVEPPAALAAVVPPETGWDAVRQARHPDRPRAQAYLEAYFELRLPLRGDRSGGADPGMLCGIGLRGGRAVAYAAQCGTATRPAGYRTAARVIRLADRLGIPVLTLVDTPGAANDAAAEQAGAGPAIADAFAALAAATVPVTTLLIGEGGSGGALALAAPGNTWVTPDSYFSVIAPELATAILKRPRAEAPATADQLRIRPQDLVALGVARGVVGPAGGA
>NZ_CP024985.1|WP_051840471.1|5653646_5654330_-|LysE-family-transporter
MSELFSPALSGAVAGLGVAMPMGAMSVLLLQEAMRHRRTAVAAAAGIAAVDLGYAALATAVGPWVASRVSPVEAWIRLFAAAVLLSIAAHALHRSARPASSTPPAPPPPGDRPPGDGTGSGGGAGGAGAVRAFGRYVGLTAVNPTTALYFAALTTAQASALTTPATAGAFLVGVAAASLLWQQTLVALGAFAGRRISPAARAWTFRLGYGLVAAYALKIAFPLPDLA
>NZ_CP024985.1|WP_030227111.1|5654400_5654841_+|Lrp/AsnC-family-transcriptional-regulator
MDRLDREILGILQQDARLSYRDLGVRVGLSANATADRVRRMRRDGVIRGFTVIVDPAADTRGGLVVFIDLVLRQDTTNEEFEQRVATLPGITEVVHVTGEYDYLVRARAADPAALDALLRRLKREAGVAQSSTRIALRAATRHPAG
>NZ_CP024985.1|WP_051840473.1|5655035_5656145_+|cation-transporter
MIVSVVSMPEGVVTRTDLPGARERLAASDFVIVDIDLGEEPEPGEEPEPGGEPAPVPGGESAPGEEPLFRGLGLDDEAWKWLGGPREPVRVEYREGTVGCVVPVLDGSRVVHVHLLASEHRLVMVHHGPVEVIETFVGRLPQDRPADPAATVFLLLHGALEGFRRAASQALLEVEDIEQAMFEQWEPRDVQRLAQLRRRAAQLHRAFRPYAAVAQEFLARRGLAHREIPEERRALHRLHESTVRLVVLEIESLRDETRRAADSYASLVADRQNLVINRLAIVSVIFLPLSFLTGFFGMNFGFMSTLMASEKAFLALGLGLQLCALVVAMYFVLYRTHWRQLRGGGPDDTADRRRRRLLQAGRRADGEGS
>NZ_CP024985.1|WP_030227120.1|5656141_5657707_-|GAF-domain-containing-protein
MTPEPPDPPDEPSSLPVLLEAVLNVGSELELRTTLQHIVESAAELCAARYGALGVVDPERARLTRLFTAGMSEAERAAVARMPDGRTGVLGALVDDPRPLLLDDLTKDPRSVGFPAGHPPMRSFLGVPIRVHTEVFGNLYLTEKAGGGPFTEEDLALVRVLASQAGIAIGNARLYETARRRERWIEGAAAVTTTLLAGRPAADALMCVAERARLLADAAAGVVLQPTPEGGMEIVAASTQGDPGDLVGTAIAPGSAVLEQLLGGEPVFIEDSATDPRMTTHVRERFGPSMMLPLQSGGQLIGTLALPRARGGPAYDAVDRLLASQFASQAALALVLADAQHDRERLAVYEDRDRIARDLHDLVVQRLFATEMMLESTRRRSSNAPSGDTVGEELSRAVDELDSTIQEVRTAIFALQQPPSDAPATFRGRVLRETGGAAVPLGFQPSVHFTGAVDALVPDPVAGDLLSALRGALAAAHRRSGVTSIEVRVDATRSRVRLTVTDDGRTEAGARGTTLRWESAL

Crispr_ID: NZ_CP024985_24

• CRISPR_ID: NZ_CP024985_24
• CRISPR_location: 7870808-7871143
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP024985_24

Consensus_repeat	Method
CGGCGGCGGCATCGCCAACGAGGG	CRISPRCasFinder

spacers of NZ_CP024985_24

>24.1|7870832|57|NZ_CP024985|CRISPRCasFinder
GACCGGTCTGCTCACGCTCAGGAAGAGCATCGTCGCGGGCAACACGGCGGACGGCGA
>24.2|7870913|51|NZ_CP024985|CRISPRCasFinder
CACGCTGATCGTCGAGTCCAGCCACTTCACGCAGAACGAGGCCCGCGACGC
>24.3|7870988|48|NZ_CP024985|CRISPRCasFinder
CTCCGCCCGGATCGAGAACAGCAGGTTCCTGGAGAACCGCGCGGGCCT
>24.4|7871060|60|NZ_CP024985|CRISPRCasFinder
CGGGATCGCGACGCTCGAAGTCCACGGGACCGCCTTCGTCGACAACAAGGCGGGCAGGGA

CRISPR arrays and Neighbor proteins around NZ_CP024985_24

CRISPR arrays

The CRISPR arrays of NZ_CP024985_24

>merge|NZ_CP024985|24|7870808-7871143|CRISPRCasFinder
CGGCGGCGGTCTCGACAACGACGCGACCGGTCTGCTCACGCTCAGGAAGAGCATCGTCGCGGGCAACACGGCGGACGGCGACGGCGGCGGCGTCCGCAACCGGGGCACGCTGATCGTCGAGTCCAGCCACTTCACGCAGAACGAGGCCCGCGACGCCGGAGGCGGCATCGGCAACCTGGGCTCCGCCCGGATCGAGAACAGCAGGTTCCTGGAGAACCGCGCGGGCCTCGACGGCGGCGCCGTCGACAACGGCGGGATCGCGACGCTCGAAGTCCACGGGACCGCCTTCGTCGACAACAAGGCGGGCAGGGACGGCGGCGCCATCGGGAACGAGGG

>NZ_CP024985|24|24|7870808-7871143|CRISPRCasFinder
CGGCGGCGGTCTCGACAACGACGC	GACCGGTCTGCTCACGCTCAGGAAGAGCATCGTCGCGGGCAACACGGCGGACGGCGA
CGGCGGCGGCGTCCGCAACCGGGG	CACGCTGATCGTCGAGTCCAGCCACTTCACGCAGAACGAGGCCCGCGACGC
CGGAGGCGGCATCGGCAACCTGGG	CTCCGCCCGGATCGAGAACAGCAGGTTCCTGGAGAACCGCGCGGGCCT
CGACGGCGGCGCCGTCGACAACGG	CGGGATCGCGACGCTCGAAGTCCACGGGACCGCCTTCGTCGACAACAAGGCGGGCAGGGA
CGGCGGCGCCATCGGGAACGAGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030230141.1|7860249_7860675_-|hypothetical-protein	unknown	unknown	gnl|CDD|368807
NZ_CP024985.1|WP_030230189.1|7880005_7881220_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP024985.1|WP_078950340.1|7868989_7870096_-|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl|CDD|224600
NZ_CP024985.1|WP_030230154.1|7865170_7866280_+|M20-family-metallopeptidase	unknown	unknown	gnl|CDD|349881
NZ_CP024985.1|WP_030230182.1|7877338_7878370_-|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|225807
NZ_CP024985.1|WP_030230139.1|7859425_7860253_-|tyrosinase-family-protein	unknown	unknown	gnl|CDD|365987
NZ_CP024985.1|WP_037687406.1|7861461_7861884_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740676.1|7871474_7872578_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030230171.1|7872620_7873241_-|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|274058
NZ_CP024985.1|WP_030230173.1|7873569_7874400_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030230176.1|7874457_7875123_+|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319829
NZ_CP024985.1|WP_030230151.1|7863118_7864687_+|amidase	unknown	unknown	gnl|CDD|235723
NZ_CP024985.1|WP_051840971.1|7867144_7868338_-|hypothetical-protein	unknown	unknown	gnl|CDD|224195
NZ_CP024985.1|WP_030230178.1|7875135_7875732_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379409
NZ_CP024985.1|WP_051840974.1|7875884_7877366_+|indole-acetimide-hydrolase	unknown	unknown	gnl|CDD|236029
NZ_CP024985.1|WP_037687410.1|7878467_7879424_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|181818
NZ_CP024985.1|WP_030230162.1|7868556_7868925_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_051840969.1|7860810_7861299_+|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376540
NZ_CP024985.1|WP_030230186.1|7879736_7879940_+|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NZ_CP024985.1|WP_030230148.1|7861898_7863122_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030230141.1|7860249_7860675_-|hypothetical-protein	gnl|CDD|368807	pfam06236, MelC1, Tyrosinase co-factor MelC1. This family consists of several tyrosinase co-factor MELC1 proteins from a number of Streptomyces species. The melanin operon (melC) of Streptomyces antibioticus contains two genes, melC1 and melC2 (apotyrosinase). It is thought that MelC1 forms a transient binary complex with the downstream apotyrosinase MelC2 to facilitate the incorporation of copper ion and the secretion of tyrosinase indicating that MelC1 is a chaperone for the apotyrosinase MelC2.	2.38739e-25
NZ_CP024985.1|WP_078950340.1|7868989_7870096_-|D-alanyl-D-alanine-carboxypeptidase	gnl|CDD|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	6.94385e-56
NZ_CP024985.1|WP_030230154.1|7865170_7866280_+|M20-family-metallopeptidase	gnl|CDD|349881	cd03885, M20_CPDG2, M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme. Peptidase M20 family, Glutamate carboxypeptidase (carboxypeptidase G; carboxypeptidase G1; carboxypeptidase G2; CPDG2; CPG2; Folate hydrolase G2; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase; E.C. 3.4.17.11) subfamily. CPDG2 is a periplasmic enzyme that is synthesized with a signal peptide. It is a dimeric zinc-dependent exopeptidase, with two domains, a catalytic domain, which provides the ligands for the two zinc ions in the active site, and a dimerization domain. CPDG2 cleaves the C-terminal glutamate moiety from a wide range of N-acyl groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl, and pteroyl groups to release benzoic acid, phenol, and aniline mustards. It is used clinically to treat methotrexate toxicity by hydrolyzing it to inactive and non-toxic metabolites. It is also proposed for use in antibody-directed enzyme prodrug therapy; for example, glutamate can be cleaved from glutamated benzoyl nitrogen mustards, producing nitrogen mustards with effective cytotoxicity against tumor cells.	1.84138e-128
NZ_CP024985.1|WP_030230182.1|7877338_7878370_-|NAD(P)H-binding-protein	gnl|CDD|225807	COG3268, COG3268, Uncharacterized conserved protein [Function unknown].	7.90193e-21
NZ_CP024985.1|WP_030230139.1|7859425_7860253_-|tyrosinase-family-protein	gnl|CDD|365987	pfam00264, Tyrosinase, Common central domain of tyrosinase. This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.	7.17957e-47
NZ_CP024985.1|WP_030230186.1|7879736_7879940_+|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	8.53978e-33
NZ_CP024985.1|WP_030230171.1|7872620_7873241_-|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	1.48098e-29
NZ_CP024985.1|WP_030230189.1|7880005_7881220_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	8.1602e-88
NZ_CP024985.1|WP_030230176.1|7874457_7875123_+|HAD-IA-family-hydrolase	gnl|CDD|319829	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). This subfamily includes Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). GPP1p and GPP2p are involved in glycerol biosynthesis, GPP1 is induced in response to both anaerobic and hyperosmotic stress, GPP2 is induced in response to hyperosmotic or oxidative stress, and during diauxic shift; overexpression of DOG1 or DOG2 confers 2-deoxyglucose resistance. These belong to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.27761e-47
NZ_CP024985.1|WP_030230151.1|7863118_7864687_+|amidase	gnl|CDD|235723	PRK06170, PRK06170, amidase; Provisional.	8.67585e-153
NZ_CP024985.1|WP_051840971.1|7867144_7868338_-|hypothetical-protein	gnl|CDD|224195	COG1276, PcoD, Putative copper export protein [Inorganic ion transport and metabolism].	2.6923e-15
NZ_CP024985.1|WP_030230178.1|7875135_7875732_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|379409	pfam13977, TetR_C_6, BetI-type transcriptional repressor, C-terminal. This family comprises the C-terminal portion of proteins that belong to the TetR family of transcriptional regulators. The C-terminus represents the regulatory region, and does not include the DNA binding helix-turn-helix domain. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. One of the target proteins is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	3.38685e-08
NZ_CP024985.1|WP_037687410.1|7878467_7879424_+|helix-turn-helix-domain-containing-protein	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	1.21329e-124
NZ_CP024985.1|WP_051840974.1|7875884_7877366_+|indole-acetimide-hydrolase	gnl|CDD|236029	PRK07487, PRK07487, amidase; Provisional.	7.17615e-130
NZ_CP024985.1|WP_051840969.1|7860810_7861299_+|XRE-family-transcriptional-regulator	gnl|CDD|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	0.00249101

Protein sequences

>NZ_CP024985.1|WP_078950340.1|7868989_7870096_-|D-alanyl-D-alanine-carboxypeptidase
MRTAVALSTDGPPRGTDPDPPVQRYAQGRVGLRTLPVGAGAEALRPSTSSPTTGADLITHLLRRARGALAVTIAAGALLTVSVPAHAAAAPPLTAAGAFLLDANSGATLTSKAPDTRRQMASTTKIMTAAVVTTLPGLNLDRRVTVKQEYLDYVYREGASSAQLKAGATPTVRQLLYAMMLPSGCDAAYALADTFGSGSTIAARKADFIAKMNAKAKALGMTNTLYDTFDGISPTGNNRTTPRDLAKLARYAMTNTLFQTLVKTTSYSSGGTSTLGTWSNTNLLVQPRPTGYGFPGATGIKTGTGTAAGKCLVFSVTRNGKTVIGVLLNDEERYADSMALSDWALGPAAGSKAALQRSSTEPVPDVRD
>NZ_CP024985.1|WP_030230162.1|7868556_7868925_+|hypothetical-protein
MTRLRTTGMALAGAAAMFALTAAPAHAAPGDVTTSCASVVTPTGYVDVSWGYSASCGTQSFNPNIKQIKQLTGLPVGTVVQACGSTYQPAGWIQTASYYSSSCVYAANGGFNNNAWTLKRVS
>NZ_CP024985.1|WP_051840971.1|7867144_7868338_-|hypothetical-protein
MNLIHLAASTGYTTPPLWRVLTKSGYFVGLCGTIGATVTYAASVRPALKGAGVPPEDAGATRRRTAGYLAWAGVVLLVAGYFQLAARVARAGKGMPFGDALAPGAVADFLTAPAGKGAWIAQGMLYLVQNVALLLAAAVLIALFLPKARRHTDALVLTALPLTLAITLIAAVPATKPKDADKVLDLVFGQTHIISGVVWIGGLALLTALSASRGRPGENAGGLWADIWRRFSLVALVCVGAVFTSGLWMSWKHVGAVSQLWTTTYGLFLLVKILLVLGMVTAGGVNQFWLMPRIVRARREDDRSSLAQLTLRHFPKVVWGEVALGVAVLAVVPFLGGSARTEAGSEAAVSSGSVFALGAVLVLTLVASLYMTVRTSDALARRTAAAPAAIPTPTPSG
>NZ_CP024985.1|WP_030230154.1|7865170_7866280_+|M20-family-metallopeptidase
MRKHRSVDVRVDSMLDDLRTLVEVESPSRDLDALGASAKTVAEVIESRLGGQAVLVESEAGPHVHWSGGGDPRVLILGHHDTVFPLGTLERRPFRVADGRATGPGVFDMLGGLVQAVHGLAALDDLSGVEILVTADEEVGSGSSRALIEERARACGAVLVFEGAADGGGLKTGRKGCGTFQVSITGRASHAGLEPAAGVNALIEAAHQVLAIDGLNRPEAGTTVTPTVASAGTLDNVVPAAATVIVDVRVESAAEQERIESAFAALVPHLDEARISVRGAVGRPPMPEAASAELFEVARRLQPGIEGKAVGGGSDGNFTAALGVPTLDGLGAVGGGAHADHEYLVVDAMVPRARLVTGLVEAIRASREA
>NZ_CP024985.1|WP_030230151.1|7863118_7864687_+|amidase
MILRRTLIVACTAVAAAAAMAGTPAAARNRAAGARPPRADLHLAPAHEQLAALRRRTVTSRALLEQTLAHIDRTNPGLGAVVTLDADGARAAADAADRHLAATGKPLGALHGLPMTLKDALETKGLRTTCGSPDLSDHVPDRDADTVARLRAAGAVIVGKTNVPVMCQDLQTSNPLFGTTRNPHDATKTAGGSSGGPAAAVAAGLTSLEVGSDLAGSLRLPAAYCGVYALRPSGGIVPTRGHIPRPPGWLTSSDMLTLGPIARDAEDLGLLLDVLAAPSPADSAAWRIDLPAPRRGRLAQYRVGVWQDDPYCHVDTDTRELLERVAALLRTAGATVDDTTRPVDLAGSDRLFQRLMYATASATAPDAGFAEDVAAADKIPADDPRGLFLHSRTMRHRDWLRANEEREELRGRWADYFATHDVLITPAAPTAAVDDQTDTPVPGRHITVDGVKRPYFDQTAWLNLAGHVSLPALVMPAGRTAAGLPLAVQIIGPYLADRTVVDLAGQLARRLPDPVRPPTATG
>NZ_CP024985.1|WP_030230148.1|7861898_7863122_+|hypothetical-protein
MKDVLHPLCLAIAGTGFLILFRDLRRSRRDPALVALAFTYGFSALSYAVSLTPVWVRIDGLLGVPNIVVPIAQGFVMLVLALQATVLAHWSKPLDEARRRSRHLLLAAGAVIATMAVLFALLTPATTRPTDFSLYYAHDPVFQAYVLLYFGMYSVAEIYLALSCWKYARTATDRSIAFSLRLVAVGAVITLGYSGIRIAAVVGAETGFSVAGLNGFAWACGDIGATLTQIGYLIPTVARRTTSALDWSATHLRYRRLAPLWTALDQADPGITLRRPARQRQDVLRGRSAHFPLLRRRVEIRQGQKLMRRYLDPTLREHAEDRRRAEGLTGAELVAAVTADQIHAALVRHRADDPVATPAEYADATLPLATTEDELLHLQRVASYFTPPTPERRDASDTRGITSGARP
>NZ_CP024985.1|WP_037687406.1|7861461_7861884_+|hypothetical-protein
MEERFDRSIRLMPFASDPADPDSLDASAPCGLWLATGDTDYVFYDTAISRAHAEIIVGHEFGHMLGRHRGDTPLAAGNLGGLITDIDPATVQLVLGRTRYNEPQEFEAELLGSLLQERLTTRVRVADTPEADPIARTLLR
>NZ_CP024985.1|WP_051840969.1|7860810_7861299_+|XRE-family-transcriptional-regulator
MVDSDSGPDGPGATRSGRVPVPGPGAPFSDRLNFLFDRVRPPGAEEYTNAHVARTISSYGEDSYTRSHISYLRAGKRTPTITMIPLLARFFGVEASYFVEDEVTRRITTQFEILRKLKENGVEQIALRAMGVSAAGQRKVLAALEAVRKEEGLPADPERDLP
>NZ_CP024985.1|WP_030230141.1|7860249_7860675_-|hypothetical-protein
MNMITRRRAFGIAVGAAAAVGLTACDKGGSAASSASASPNAEASGPALSIPTGGIDEVYEGRRIQITLDPGAHHDGQHMPGMPNIKIDGKELHLMRNADNSWVTVVNHYETFADPISAAKAAVRDLQGANLLPFAPTGGTP
>NZ_CP024985.1|WP_030230139.1|7859425_7860253_-|tyrosinase-family-protein
MTVRKSQSKLTAEEKRAFTNALLELKRTGVYDRYVNAHNAFLMSDSDFGDRVGHRAPSFLPWHRRFLLDFEAALQKVDPKVSLPYWDWTVDRTPSSSLWAADFLGGTNRARDGQVLDGPFAYAGGKWAITVGVDARTYLRRTLGAGGAQLPTKDEVNSVLAMPVYDSAPWNSTSGGFRNHLEGWRGPGLHNKVHVWVGGHMASAASPNDPVFWMHHAFIDMLWSEWQRRNPKSAYLPAAPTANVVDFHGKLRPWNDVTPADLMDHRKFYTFDTER
>NZ_CP024985.1|WP_158740676.1|7871474_7872578_+|hypothetical-protein
MSHNTGWEHHHPQQPAPQWGGGWAPPPPPPQPGVVPLRPLGVGDLLGGAFSAFRRYWKPLAGVILGVQGIGILLVAVAIGVAALSVDTHFAEVFDPAPGERPTGADVMALLVYFVPALVLMLVTMALGMAMIAALCPAVIQEAVLGRPTTFRAMWRRCWSRMPSVLGVVLLVGLIAGGPVIVLYVVCFPLVFMASDGSGPPAAVFLMFLGVLLWIPVSVWLAVRFSLAPAVAVCEGLGPVASLRRSTRLVSGGWWRVFGVSLLAYLLSAAVGYIIQLPFTFLGMFALFPSMLAAGDEASDATVLIVGIVVYALCVLLGIVISGVFQFGFPQLVVSLLYVDQRMRKENLAEGLIAEVHAPTVPVPGQV
>NZ_CP024985.1|WP_030230171.1|7872620_7873241_-|RNA-2',3'-cyclic-phosphodiesterase
MTETPEHATQPPADERGTAPTVRVFVALAPPDDAKAELERELGPAYHAHPRMRWNRIEDWHITLAFLGELPVAAVPPLRPALAALAASRAPLRLSLRGGGHFDERVLWTGIDGDLEGLHRLATDVRALVRECGIDFRERPLRPHLTLARSRRGAHSSAVEAAAGLTGFTGRPWPAERLHLVGSNIGRGPGPIHYRDIESWGFDGEG
>NZ_CP024985.1|WP_030230173.1|7873569_7874400_+|hypothetical-protein
MTPFDEIYDRPDPRDFFRGLGRWQYRTPHHAQDVFRRLVAARRRAGAAEPPAVLDICCSYGINAALLNHDLTLDDLYAHYTSPRAAALTTAELIERDRAYYAARRRPDAVPVIGLDPAAGAIAYACSVGLLDEGFASNLETEPPGARLLAAVRRVGLITVTGGASFLSPRTFRPLLGAAREQVWVAAFVLRTGSYRTIADGLAPFGLITEKVAEPTYPQRRFTSPAEQRHAVDAVTALGEDPRGKEDAGWFHTAFHLSRPSPDTTAVPLSTFLREV
>NZ_CP024985.1|WP_030230176.1|7874457_7875123_+|HAD-IA-family-hydrolase
MTSESNQPTGRRTHVLFDVDGTLIDALDNQRRVWRTWARRHGLDPDEVHRVALRTRPVETFAQVAPDRDPQECLAALHELEDEDVRSGVYTAFDGAAELLSRLPSASWALVTSNYEHRVRGRFARTGLPVPALIVDAAAVGEGKPSPAPYLSAAARLGADPRDCLVVEDAPSGVLSGLRAGMTVWGVNTPHAVEGVHRHYPTLREAVPDILAFASAGRGSR
>NZ_CP024985.1|WP_030230178.1|7875135_7875732_-|TetR/AcrR-family-transcriptional-regulator
MPRQVDHADRRRIVAEAVCELADEHGLEGVTLRDVAARAQVSMGAVQRCFRTKEEMLVFALGHIGERIGSRVRARLVRSPAQSAATALGHAATEVALLREEHRAEARVWLAFVAQAAVSEALAGTLKASYAALEESFAGLVAEALEDPARTVPVDPRREARTLLALADGLTAHVLIGHLTPRAAQDVLDAHLTALFTD
>NZ_CP024985.1|WP_051840974.1|7875884_7877366_+|indole-acetimide-hydrolase
MRDALWRMTAGAQARAVREGEVSALELVDSHLERIAEVNPRVNAVTATLADRAREAAARTDRRRAAGEVLGPLAGVPFTVKESTPVEGVPTTFGVERFRDLLAPADALPVARLRAAGAVPVGHSNMPTLVLAGMHTRSELFGDTVNPWDPARTPGGTSGGDGVAVATGMAALGLGNDSGGSVRIPAQFCGVAALKPTSGRFPADRRVIGPDDPGPASQFLVTDGPLARSVDDLRLAYEVLAGPDPRDPLAMPVPAYGEPLPGPVKVAVVTDPGGHGVHPAVRAAVETAAAALRDAGYDVREVPDVPRLDEALDAYGRITATEFAPAWPVVRGLLGKGGDRYIAMAMERTPPATADELVALMGTWLGIRRSWAEFLDGYPLLLGPVFTEPPVEPGLESRDRAGRDRVATAMRLCTVTSFVGVPAVAVPTGVTDGLPCGVQIVGRAFREDLCLAAARAVEERLGVLAPIDPRQEARAGAAPLRVPAPHAGRSTET
>NZ_CP024985.1|WP_030230182.1|7877338_7878370_-|NAD(P)H-binding-protein
MSTAAAVVVYGATGHTGRFVVAELLRRGVSTVVSGRNAERLEELAAQWGGVVVRAAGVDDPDALDRALAGAAAVINCAGPFAVTAGPVVEAALRAGIPYVDVAAEIEANAATFADHAEAARRAGVAVVPAMAFYGGLGDLLVTAALGGRTAADEVHVAYGLDSWHPTEGTRAAGAVSHERRGGRRVRFADGALRYHDDEPRKVHWDFPEPLGRRPVIAEFTMADVVTVPSHLEVPEVRTYMSVEAAGDLAAQDTPVPEAVDALGRSAQLFAVDVLVRTDGAERRATARGQDIYAVTAPLAVEAVQRLLSGRARATGVVSAGAVFDAADFLRALAPYVSVDLPA
>NZ_CP024985.1|WP_037687410.1|7878467_7879424_+|helix-turn-helix-domain-containing-protein
MPTVALLAAGDLLHFELGVAYEIFGNPPREAVDGWYDVLLCGPGPVRVGPFRVEPDHGLEHLATADTVIVPACADIDVPPSPELVDAVRTAHEAGARVASLCTGAFLLGAAGLLDGRRATTHWAHAEELSTRHPRAVVDPDVLYTDNGSVLTAAGKAAAVDLCLHLVHLDHGALIANSVARRLVMPPHRPGGQAQFVASPVPARGDHVLADLLAWVLERLDRPLTVADMARKANTSPRHLGRQFRSVTGQPPLQWLLTQRVRRAQELLEATGMSVESVALATGMGTATTLRRQFKRTVGVPPDTYRRAFRSANPTPDP
>NZ_CP024985.1|WP_030230186.1|7879736_7879940_+|cold-shock-protein
MASGIVKWFNSEKGFGFIAQDGGGPDVFAHYSNINSTGYRELQEGQAVTFDVTQGQKGPQAENITVA
>NZ_CP024985.1|WP_030230189.1|7880005_7881220_-|cytochrome-P450
MTPISHDATLPQPFGEPFARDPHAVYATLRAAGPVHRVALPDGSPVWLVVREADVRAGLSDQRLSVDKKHSATGFSGFSLPPALDANLLNVGPEDHLRLRGLVARGFTPRHVDRLRDTVRAAVEERTGHLARRLDGGGEADLVAEFARPLPLRVIGALLDVPSGDRERFSGWISTMLTPGSREELVRAIGEVHRFLVGLVAERRARPGDDVLSDLIPARDEGDRLTEEELVSLAFLILGAGSENVQHVISAGVLTLLDHPEQLARLRAEPARMADAVEELLRYTSPNQTAIRRFPTEPVEIGGVRIPAGDTVLFALASAHRDPDRYPDPDRFDIDRADKAHLALGHGMHYCLGAPLARLQLTLALGAVVDRFPGLRPARRADGLRWHSTFRFRALRELPVTAVR

Crispr_ID: NZ_CP024985_26

• CRISPR_ID: NZ_CP024985_26
• CRISPR_location: 8625841-8626535
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 9 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_26

Consensus_repeat	Method
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CRISPRCasFinder
GACCGAGGATCGCAAC	PILER-CR

spacers of NZ_CP024985_26

>26.1|8625878|37|NZ_CP024985|CRISPRCasFinder
TGCACGGCGGTGCTGATTCCGGCGCCCATGCCGTTGA
>26.2|8625952|35|NZ_CP024985|CRISPRCasFinder
CAGACCAGACCGGTGGAGCCCCGGCCGTCCGCCGC
>26.3|8626024|37|NZ_CP024985|CRISPRCasFinder
GACCACGACCAGGCCGCAGAGCAACAGCGCGCGGCGG
>26.4|8626098|37|NZ_CP024985|CRISPRCasFinder
CACCAGCACACGGACAACCCGATCGATACGGACTACT
>26.5|8626172|37|NZ_CP024985|CRISPRCasFinder
AGGGTGTCGGCGGGGCCTGTCGTGTGGGGGAGTGCGG
>26.6|8626246|36|NZ_CP024985|CRISPRCasFinder
AACCAGATTGCCGATGCTCTCGGCCTGGACGAGCAG
>26.7|8626319|38|NZ_CP024985|CRISPRCasFinder
CAGGCTGGCCCGGTACGCGAGCCGCGTCGGCTGCTGGG
>26.8|8626394|33|NZ_CP024985|CRISPRCasFinder
GTCGAGCGCGCGCGGTGGACCTGTACGACGATG
>26.9|8626464|35|NZ_CP024985|CRISPRCasFinder
CTCTTCCACGTCGCACTCAGCCGGATGCGGGCCGG
>26.10|8625878|58|NZ_CP024985|PILER-CR
TGCACGGCGGTGCTGATTCCGGCGCCCATGCCGTTGAGTGGCGGTCGCCCTTCGGGAC
>26.11|8625952|56|NZ_CP024985|PILER-CR
CAGACCAGACCGGTGGAGCCCCGGCCGTCCGCCGCGCGGCGGTCGCCCTTCGGGGC
>26.12|8626024|58|NZ_CP024985|PILER-CR
GACCACGACCAGGCCGCAGAGCAACAGCGCGCGGCGGGTGGAAGTTGTCCTTCGGGGT
>26.13|8626098|58|NZ_CP024985|PILER-CR
CACCAGCACACGGACAACCCGATCGATACGGACTACTGTGGCGGTTGCCCTCAGGGGT
>26.14|8626172|58|NZ_CP024985|PILER-CR
AGGGTGTCGGCGGGGCCTGTCGTGTGGGGGAGTGCGGGTGGCGGTCGCCGTTCGGGAC

CRISPR arrays and Neighbor proteins around NZ_CP024985_26

CRISPR arrays

The CRISPR arrays of NZ_CP024985_26

>merge|NZ_CP024985|26|8625841-8626535|CRISPRCasFinder,PILER-CR
GGGGCGGTCGCCTTTCGGGACGACCGAGGATCGCAACTGCACGGCGGTGCTGATTCCGGCGCCCATGCCGTTGAGTGGCGGTCGCCCTTCGGGACGACCAAGGATCGCAACCAGACCAGACCGGTGGAGCCCCGGCCGTCCGCCGCGCGGCGGTCGCCCTTCGGGGCGACCGAGGATCGCAACGACCACGACCAGGCCGCAGAGCAACAGCGCGCGGCGGGTGGAAGTTGTCCTTCGGGGTGACTGAGGATCGCAACCACCAGCACACGGACAACCCGATCGATACGGACTACTGTGGCGGTTGCCCTCAGGGGTGACTGAGGATCGCAACAGGGTGTCGGCGGGGCCTGTCGTGTGGGGGAGTGCGGGTGGCGGTCGCCGTTCGGGACGACCGAGGATCGCAACAACCAGATTGCCGATGCTCTCGGCCTGGACGAGCAGGTGGTGGTAGCCCTTCGGGGCGACGGTGGATCGCAGCCAGGCTGGCCCGGTACGCGAGCCGCGTCGGCTGCTGGGGTCGTAGTCGTCCTCCCGCACGACTGAGGAACGAAACGTCGAGCGCGCGCGGTGGACCTGTACGACGATGGTGGCGGTCGCCCTTCGGAACGGCCGAGGATCGCAACCTCTTCCACGTCGCACTCAGCCGGATGCGGGCCGGCGTGGCGGTCGCCCTCGGGACGACCGGGGATCGCAAC

>NZ_CP024985|26|26|8625841-8626535|CRISPRCasFinder
GGGGCGGTCGCCTTTCGGGACGACCGAGGATCGCAAC	TGCACGGCGGTGCTGATTCCGGCGCCCATGCCGTTGA
GTGGCGGTCGCCCTTCGGGACGACCAAGGATCGCAAC	CAGACCAGACCGGTGGAGCCCCGGCCGTCCGCCGC
GCGGCGGTCGCCCTTCGGGGCGACCGAGGATCGCAAC	GACCACGACCAGGCCGCAGAGCAACAGCGCGCGGCGG
GTGGAAGTTGTCCTTCGGGGTGACTGAGGATCGCAAC	CACCAGCACACGGACAACCCGATCGATACGGACTACT
GTGGCGGTTGCCCTCAGGGGTGACTGAGGATCGCAAC	AGGGTGTCGGCGGGGCCTGTCGTGTGGGGGAGTGCGG
GTGGCGGTCGCCGTTCGGGACGACCGAGGATCGCAAC	AACCAGATTGCCGATGCTCTCGGCCTGGACGAGCAG
GTGGTGGTAGCCCTTCGGGGCGACGGTGGATCGCAGC	CAGGCTGGCCCGGTACGCGAGCCGCGTCGGCTGCTGGG
GTCGTAGTCGTCCTCCCGCACGACTGAGGAACGAAAC	GTCGAGCGCGCGCGGTGGACCTGTACGACGATG
GTGGCGGTCGCCCTTCGGAACGGCCGAGGATCGCAAC	CTCTTCCACGTCGCACTCAGCCGGATGCGGGCCGG
CGTGGCGGTCGCCCTCGGGACGACCGGGGATCGCAAC

>NZ_CP024985|26|11|8625862-8626245|PILER-CR
GACCGAGGATCGCAAC	TGCACGGCGGTGCTGATTCCGGCGCCCATGCCGTTGAGTGGCGGTCGCCCTTCGGGAC
GACCAAGGATCGCAAC	CAGACCAGACCGGTGGAGCCCCGGCCGTCCGCCGCGCGGCGGTCGCCCTTCGGGGC
GACCGAGGATCGCAAC	GACCACGACCAGGCCGCAGAGCAACAGCGCGCGGCGGGTGGAAGTTGTCCTTCGGGGT
GACTGAGGATCGCAAC	CACCAGCACACGGACAACCCGATCGATACGGACTACTGTGGCGGTTGCCCTCAGGGGT
GACTGAGGATCGCAAC	AGGGTGTCGGCGGGGCCTGTCGTGTGGGGGAGTGCGGGTGGCGGTCGCCGTTCGGGAC
GACCGAGGATCGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239906.1|8609746_8610253_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NZ_CP024985.1|WP_030239899.1|8612384_8612600_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_030239901.1|8611064_8612297_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	9.19178e-87
NZ_CP024985.1|WP_030239899.1|8612384_8612600_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.62772e-14
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_030239901.1|8611064_8612297_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.96529e-05
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57

Protein sequences

>NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase
MTTLAPQAVVRLGTRPSPMAMEQTGRFAQAFHACHPQLTLDIRKITSEGDAHRGPLSQIGGKGAFTRRADTHLLDGRVDATIACAKDLPGSHDRAPGTAVAAVLPREDVRDVLVLPVGHQPVTLAELPPGTRVGTSAPRRAALLASLFPQLVPVPIRGNADSRLDRLDHGRLGADVMIAALAGLRRLGFADRAGEVLDPTLWLPATGAGIIVVEHRADDTVTGGLLAPLTHPATRILLDAERAVLAELAGGCLTAASAHATLDDTGRVIVRAAVLDPAGGPSVRAEASGSTEHAAEIGRRTARALLNAGALRLLAVTHE
>NZ_CP024985.1|WP_030239899.1|8612384_8612600_-|DUF397-domain-containing-protein
MGDAVPVGVAWQKSAACNGYEDCVEVARLANGNVGVRNSRLPDGPMVQFTSAELAAFLDGVGKGEFDWMTS
>NZ_CP024985.1|WP_030239901.1|8611064_8612297_-|helix-turn-helix-domain-containing-protein
MADRPSHPLARLVDPEGLDRHQSGTTLARRLWGLELREARDNLGWTGAEAVQRGAVSSTTVLSRLEQGKLRAKVTTSVAEALVRAYGVDEVTAVSWRSQAAAIENERSRPGGEVAVVDGDFSASPAFEDILRLERRASEIISFAGVFVPGRVQTRQYSRVVMERACDGRPELLVRVPERLRQRHQRQELLEWGTALHYSMIIDEHVLTTPIPGEAPMLEQLLELQKLARSREWIHLRVLPRSQWAHELPKAMTMSLFRFPAEQAESGEAAAPPAILYLEGSSPEVSRLYTDQARVDQHDANLNMLSNLSLDAEDSLGFIQEQVSRFEAKLRGGAAVRHGCTGAGLSRYAGHSPVLDPAGGGAGLGLGGMTRVPAGHVAGGVLSQHGEAGEEAGDVVAGTDVAPVPTQRVP
>NZ_CP024985.1|WP_030239906.1|8609746_8610253_+|hypothetical-protein
MITAFSGRVPHASPVLEACGTGAAARTGRKDVRAAEQTARTAFKARFDSAYRQYAAVRLGDDDAGDVVEAVWKQIELGWAGLLRCPSPAGGAWTLLSRAVHASPARPPSPLDKLPRPAADAFLLRHCVGLEADRAAEAMGMEPAAFESLYRSVVPRPGSGNPSGIFDR
>NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP

Crispr_ID: NZ_CP024985_25

• CRISPR_ID: NZ_CP024985_25
• CRISPR_location: 8624088-8625734
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 22 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_25

Consensus_repeat	Method
GTTGCGATCCTCGGTCGTCCCGAAGGACGACCGCCAC	PILER-CR
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CRISPRCasFinder
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CRT
CTTCGGGACGACCGAGGATCGCAAC	PILER-CR
GCGTTGCGATCCTCGGTCGCCCCGAAGGACGACCGCCAC	PILER-CR

spacers of NZ_CP024985_25

>25.1|8624125|37|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
CTGACGTTCTGGGCAGCGAAGGAGTCGGCGGAGGCGG
>25.2|8624199|36|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
GCCATCGGCGCCGTGGCCTGGTGCGTGCCGTACGTG
>25.3|8624272|37|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
AGCGCACCCGCATCGAGCAGCTGTCCTGGGTGCTGGT
>25.4|8624346|37|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
CCCAAGCCCGCCCGGGGCCAGAACGGGAAGGGTGGCG
>25.5|8624420|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
CACAGGCCGAAGTGGGCGAGGACACCGGTCGCGAA
>25.6|8624492|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
CTGACTGCGAGACGTCCGCCGGAGCATCCGCCACG
>25.7|8624564|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
AACCCAGCAGGTCACGGCCGCCATCAGGGACGGGA
>25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
GCCGCGGCCCTGGCCCGGATCACCGACGAAGTGCT
>25.9|8624708|37|NZ_CP024985|CRISPRCasFinder,CRT
ACCTTCCGCGTGGGCAGGGGCGGGCAGCGCCGGGCGG
>25.10|8624782|36|NZ_CP024985|CRISPRCasFinder,CRT
CAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAG
>25.11|8624855|39|NZ_CP024985|CRISPRCasFinder,CRT
CTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGT
>25.12|8624931|34|NZ_CP024985|CRISPRCasFinder,CRT
CCCGAACCGGGGACCCCCCGTGATGATCAGATTC
>25.13|8625002|36|NZ_CP024985|CRISPRCasFinder,CRT
GGCGCGCTCGTGAAGGAGATGAAGAAGCGCGGGCTG
>25.14|8625075|36|NZ_CP024985|CRISPRCasFinder,CRT
TCGGAATCGCCTCGCTCCTCGGTCTCGACTGGTCCG
>25.15|8625148|37|NZ_CP024985|CRISPRCasFinder,CRT
CCGCTTCCTGCTCGTCGTACAGCTCGGCGGCGCGGGC
>25.16|8625222|38|NZ_CP024985|CRISPRCasFinder,CRT
ACCAGCGGCACGACAGGCACGTCGGCCGGCACGCCGGG
>25.17|8625297|36|NZ_CP024985|CRISPRCasFinder,CRT
ACGCTCCTCCGTCTGGCGGAAGTGGGCGGAGTCGGG
>25.18|8625370|36|NZ_CP024985|CRISPRCasFinder,CRT
GCCGGAACGCTCGACAGCCGAGTGCGCCGAGCCCTC
>25.19|8625443|36|NZ_CP024985|CRISPRCasFinder,CRT
GCGTACTCCGCGATCCGGAAGGCGAGTTCGCCGACG
>25.20|8625516|36|NZ_CP024985|CRISPRCasFinder
TGTCGAGCGCGCGTGGTGGACCTGTACGACGATGGT
>25.21|8625589|36|NZ_CP024985|CRISPRCasFinder
CGGAGTTACAGATTCGGAGGTGACGCCATGGCTGTG
>25.22|8625662|35|NZ_CP024985|CRISPRCasFinder
GACTGGCCGAACGTACAGCGGGCGACCCGGTGCGG
>25.23|8624782|48|NZ_CP024985|PILER-CR
CAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAGGTGGCGGTCGCC
>25.24|8624855|51|NZ_CP024985|PILER-CR
CTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGTGTGGCGGTCGTC
>25.25|8624931|53|NZ_CP024985|PILER-CR
CCCGAACCGGGGACCCCCCGTGATGATCAGATTCGGAGTGGCGGTCCCTCGCT
>25.26|8625009|48|NZ_CP024985|PILER-CR
GGCGCGCTCGTGAAGGAGATGAAGAAGCGCGGGCTGGTGGCGGTTGTC
>25.27|8625082|52|NZ_CP024985|PILER-CR
TACGTCGGAATCGCCTCGCTCCTCGGTCTCGACTGGTCCGGTGGCGGTCGTC
>25.28|8625304|36|NZ_CP024985|PILER-CR
ACGCTCCTCCGTCTGGCGGAAGTGGGCGGAGTCGGG
>25.29|8625380|34|NZ_CP024985|PILER-CR
CGGAACGCTCGACAGCCGAGTGCGCCGAGCCCTC

CRISPR arrays and Neighbor proteins around NZ_CP024985_25

CRISPR arrays

The CRISPR arrays of NZ_CP024985_25

>merge|NZ_CP024985|25|8624088-8625734|PILER-CR,CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACCTGACGTTCTGGGCAGCGAAGGAGTCGGCGGAGGCGGGTGGCGGTCGTCCTTCGGGACGGCCGAGGATCGCAACGCCATCGGCGCCGTGGCCTGGTGCGTGCCGTACGTGGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACAGCGCACCCGCATCGAGCAGCTGTCCTGGGTGCTGGTGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACCCCAAGCCCGCCCGGGGCCAGAACGGGAAGGGTGGCGGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACCACAGGCCGAAGTGGGCGAGGACACCGGTCGCGAAGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACCTGACTGCGAGACGTCCGCCGGAGCATCCGCCACGGTGGCGGTCGTCTTTCGGGACGACCGAGGATCGCAACAACCCAGCAGGTCACGGCCGCCATCAGGGACGGGAGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACGCCGCGGCCCTGGCCCGGATCACCGACGAAGTGCTGTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAACACCTTCCGCGTGGGCAGGGGCGGGCAGCGCCGGGCGGGTGGCGGTCGCGCTTCGGGACGACCGAGGATCGCAACCAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAGGTGGCGGTCGCCCTTCGAGCTGACCGAGGATCGCAACCTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGTGTGGCGGTCGTCCTTTGGGACGACCGAGGATCGCAACCCCGAACCGGGGACCCCCCGTGATGATCAGATTCGGAGTGGCGGTCCCTCGCTACGACCGAGGATCGCAACGGCGCGCTCGTGAAGGAGATGAAGAAGCGCGGGCTGGTGGCGGTTGTCCTTCGGGACGACCGAGGATCGTACGTCGGAATCGCCTCGCTCCTCGGTCTCGACTGGTCCGGTGGCGGTCGTCCTTCGGGACGATCGAGGATCGCAACCCGCTTCCTGCTCGTCGTACAGCTCGGCGGCGCGGGCTTGGCGGTTGCCCTTCAGGACGACCGAGGATCGCAACACCAGCGGCACGACAGGCACGTCGGCCGGCACGCCGGGGTGGCGGTCTCCCTTCGGGGCGACCGAGAATCGCAACACGCTCCTCCGTCTGGCGGAAGTGGGCGGAGTCGGGGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACGCCGGAACGCTCGACAGCCGAGTGCGCCGAGCCCTCGTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAACGCGTACTCCGCGATCCGGAAGGCGAGTTCGCCGACGGTGGCGGTCGTCCTCCCACGCGACTGAGGGAACGAAATGTCGAGCGCGCGTGGTGGACCTGTACGACGATGGTGGCGGTCGTCTGCTTCGGGACGACCGAGGATCGCAACCGGAGTTACAGATTCGGAGGTGACGCCATGGCTGTGGTGGCGGTCGTCCTTCGGGACGATCGAGGATCGCAACGACTGGCCGAACGTACAGCGGGCGACCCGGTGCGGGTGGCGGTTGCCCCTCGGGGTGACCGAGGTTCGCAACC

>NZ_CP024985|25|8|8624088-8624707|PILER-CR
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACGTTCTGGGCAGCGAAGGAGTCGGCGGAGGCGG
GTGGCGGTCGTCCTTCGGGACGGCCGAGGATCGCAAC	GCCATCGGCGCCGTGGCCTGGTGCGTGCCGTACGTG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	AGCGCACCCGCATCGAGCAGCTGTCCTGGGTGCTGGT
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CCCAAGCCCGCCCGGGGCCAGAACGGGAAGGGTGGCG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CACAGGCCGAAGTGGGCGAGGACACCGGTCGCGAA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACTGCGAGACGTCCGCCGGAGCATCCGCCACG
GTGGCGGTCGTCTTTCGGGACGACCGAGGATCGCAAC	AACCCAGCAGGTCACGGCCGCCATCAGGGACGGGA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GCCGCGGCCCTGGCCCGGATCACCGACGAAGTGCT
GTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAACACCTTCCGCGTGGGCAGGGGCGGGCAGCGCCGGGCGGGTGGCGGTCGCGCTTCGGGACGACCGAGGATCGCAAC	CAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAGGTGGCGGTCGCC
CTTCGAGCTGACCGAGGATCGCAAC	CTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGTGTGGCGGTCGTC
CTTTGGGACGACCGAGGATCGCAAC	CCCGAACCGGGGACCCCCCGTGATGATCAGATTCGGAGTGGCGGTCCCTCGCT
ACGACCGAGGATCGCAACGGCGCGC	TCGTGAAGGAGATGAAGAAGCGCGGGCTGGTGGCGGTTGTCCTTCGGG
ACGACCGAGGATCGTACGTCGGAAT	CGCCTCGCTCCTCGGTCTCGACTGGTCCGGTGGCGGTCGTCCTTCGGGACGA
TCGAGGATCGCAACCCGCTTCCTGCTCGTCGTACAGCTCGGCGGCGCGGGCTTGGCGGTTGCCCTTCAGGACGACCGAGGATCGCAACACCAGCGGCACGACAGGCACGTCGGCCGGCACGCCGGGGTGGCGGTCTCCCTTCGGGGCGACCGAGAATCGCAACACGCTCC	TCCGTCTGGCGGAAGTGGGCGGAGTCGGGGTGGCGG
TCGTCCTTCGGGACGACCGAGGATCGCAACGCCGGAACGC	TCGACAGCCGAGTGCGCCGAGCCCTCGTGGCGGT


>NZ_CP024985|25|25|8624088-8625734|CRISPRCasFinder
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACGTTCTGGGCAGCGAAGGAGTCGGCGGAGGCGG
GTGGCGGTCGTCCTTCGGGACGGCCGAGGATCGCAAC	GCCATCGGCGCCGTGGCCTGGTGCGTGCCGTACGTG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	AGCGCACCCGCATCGAGCAGCTGTCCTGGGTGCTGGT
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CCCAAGCCCGCCCGGGGCCAGAACGGGAAGGGTGGCG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CACAGGCCGAAGTGGGCGAGGACACCGGTCGCGAA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACTGCGAGACGTCCGCCGGAGCATCCGCCACG
GTGGCGGTCGTCTTTCGGGACGACCGAGGATCGCAAC	AACCCAGCAGGTCACGGCCGCCATCAGGGACGGGA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GCCGCGGCCCTGGCCCGGATCACCGACGAAGTGCT
GTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAAC	ACCTTCCGCGTGGGCAGGGGCGGGCAGCGCCGGGCGG
GTGGCGGTCGCGCTTCGGGACGACCGAGGATCGCAAC	CAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAG
GTGGCGGTCGCCCTTCGAGCTGACCGAGGATCGCAAC	CTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGT
GTGGCGGTCGTCCTTTGGGACGACCGAGGATCGCAAC	CCCGAACCGGGGACCCCCCGTGATGATCAGATTC
GGAGTGGCGGTCCCTCGCTACGACCGAGGATCGCAAC	GGCGCGCTCGTGAAGGAGATGAAGAAGCGCGGGCTG
GTGGCGGTTGTCCTTCGGGACGACCGAGGATCGTACG	TCGGAATCGCCTCGCTCCTCGGTCTCGACTGGTCCG
GTGGCGGTCGTCCTTCGGGACGATCGAGGATCGCAAC	CCGCTTCCTGCTCGTCGTACAGCTCGGCGGCGCGGGC
TTGGCGGTTGCCCTTCAGGACGACCGAGGATCGCAAC	ACCAGCGGCACGACAGGCACGTCGGCCGGCACGCCGGG
GTGGCGGTCTCCCTTCGGGGCGACCGAGAATCGCAAC	ACGCTCCTCCGTCTGGCGGAAGTGGGCGGAGTCGGG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GCCGGAACGCTCGACAGCCGAGTGCGCCGAGCCCTC
GTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAAC	GCGTACTCCGCGATCCGGAAGGCGAGTTCGCCGACG
GTGGCGGTCGTCCTCCCACGCGACTGAGGGAACGAAA	TGTCGAGCGCGCGTGGTGGACCTGTACGACGATGGT
GGCGGTCGTCTGCTTCGGGACGACCGAGGATCGCAAC	CGGAGTTACAGATTCGGAGGTGACGCCATGGCTGTG
GTGGCGGTCGTCCTTCGGGACGATCGAGGATCGCAAC	GACTGGCCGAACGTACAGCGGGCGACCCGGTGCGG
GTGGCGGTTGCCCCTCGGGGTGACCGAGGTTCGCAACC

>NZ_CP024985|25|6|8624088-8625515|CRT
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACGTTCTGGGCAGCGAAGGAGTCGGCGGAGGCGG
GTGGCGGTCGTCCTTCGGGACGGCCGAGGATCGCAAC	GCCATCGGCGCCGTGGCCTGGTGCGTGCCGTACGTG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	AGCGCACCCGCATCGAGCAGCTGTCCTGGGTGCTGGT
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CCCAAGCCCGCCCGGGGCCAGAACGGGAAGGGTGGCG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CACAGGCCGAAGTGGGCGAGGACACCGGTCGCGAA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACTGCGAGACGTCCGCCGGAGCATCCGCCACG
GTGGCGGTCGTCTTTCGGGACGACCGAGGATCGCAAC	AACCCAGCAGGTCACGGCCGCCATCAGGGACGGGA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GCCGCGGCCCTGGCCCGGATCACCGACGAAGTGCT
GTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAAC	ACCTTCCGCGTGGGCAGGGGCGGGCAGCGCCGGGCGG
GTGGCGGTCGCGCTTCGGGACGACCGAGGATCGCAAC	CAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAG
GTGGCGGTCGCCCTTCGAGCTGACCGAGGATCGCAAC	CTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGT
GTGGCGGTCGTCCTTTGGGACGACCGAGGATCGCAAC	CCCGAACCGGGGACCCCCCGTGATGATCAGATTC
GGAGTGGCGGTCCCTCGCTACGACCGAGGATCGCAAC	GGCGCGCTCGTGAAGGAGATGAAGAAGCGCGGGCTG
GTGGCGGTTGTCCTTCGGGACGACCGAGGATCGTACG	TCGGAATCGCCTCGCTCCTCGGTCTCGACTGGTCCG
GTGGCGGTCGTCCTTCGGGACGATCGAGGATCGCAAC	CCGCTTCCTGCTCGTCGTACAGCTCGGCGGCGCGGGC
TTGGCGGTTGCCCTTCAGGACGACCGAGGATCGCAAC	ACCAGCGGCACGACAGGCACGTCGGCCGGCACGCCGGG
GTGGCGGTCTCCCTTCGGGGCGACCGAGAATCGCAAC	ACGCTCCTCCGTCTGGCGGAAGTGGGCGGAGTCGGG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GCCGGAACGCTCGACAGCCGAGTGCGCCGAGCCCTC
GTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAAC	GCGTACTCCGCGATCCGGAAGGCGAGTTCGCCGACG
GTGGCGGTCGTCCTCCCACGCGACTGAGGGAACGAAA

>NZ_CP024985|25|9|8624757-8625147|PILER-CR
	CTGACGTTCTGGGCAGCGAAGGAGTCGGCGGAGGCGG
GTGGCGGTCGTCCTTCGGGACGGCCGAGGATCGCAAC	GCCATCGGCGCCGTGGCCTGGTGCGTGCCGTACGTG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	AGCGCACCCGCATCGAGCAGCTGTCCTGGGTGCTGGT
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CCCAAGCCCGCCCGGGGCCAGAACGGGAAGGGTGGCG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CACAGGCCGAAGTGGGCGAGGACACCGGTCGCGAA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACTGCGAGACGTCCGCCGGAGCATCCGCCACG
GTGGCGGTCGTCTTTCGGGACGACCGAGGATCGCAAC	AACCCAGCAGGTCACGGCCGCCATCAGGGACGGGA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GCCGCGGCCCTGGCCCGGATCACCGACGAAGTGCT
GTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAACACCTTCCGCGTGGGCAGGGGCGGGCAGCGCCGGGCGGGTGGCGGTCGCGCTTCGGGACGACCGAGGATCGCAAC	CAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAGGTGGCGGTCGCC
CTTCGAGCTGACCGAGGATCGCAAC	CTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGTGTGGCGGTCGTC
CTTTGGGACGACCGAGGATCGCAAC	CCCGAACCGGGGACCCCCCGTGATGATCAGATTCGGAGTGGCGGTCCCTCGCT
ACGACCGAGGATCGCAACGGCGCGC	TCGTGAAGGAGATGAAGAAGCGCGGGCTGGTGGCGGTTGTCCTTCGGG
ACGACCGAGGATCGTACGTCGGAAT	CGCCTCGCTCCTCGGTCTCGACTGGTCCGGTGGCGGTCGTCCTTCGGGACGA
TCGAGGATCGCAACCCGCTTCCTGCTCGTCGTACAGCTCGGCGGCGCGGGCTTGGCGGTTGCCCTTCAGGACGACCGAGGATCGCAACACCAGCGGCACGACAGGCACGTCGGCCGGCACGCCGGGGTGGCGGTCTCCCTTCGGGGCGACCGAGAATCGCAACACGCTCC	TCCGTCTGGCGGAAGTGGGCGGAGTCGGGGTGGCGG
TCGTCCTTCGGGACGACCGAGGATCGCAACGCCGGAACGC	TCGACAGCCGAGTGCGCCGAGCCCTCGTGGCGGT


>NZ_CP024985|25|10|8625264-8625445|PILER-CR
	CTGACGTTCTGGGCAGCGAAGGAGTCGGCGGAGGCGG
GTGGCGGTCGTCCTTCGGGACGGCCGAGGATCGCAAC	GCCATCGGCGCCGTGGCCTGGTGCGTGCCGTACGTG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	AGCGCACCCGCATCGAGCAGCTGTCCTGGGTGCTGGT
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CCCAAGCCCGCCCGGGGCCAGAACGGGAAGGGTGGCG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CACAGGCCGAAGTGGGCGAGGACACCGGTCGCGAA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CTGACTGCGAGACGTCCGCCGGAGCATCCGCCACG
GTGGCGGTCGTCTTTCGGGACGACCGAGGATCGCAAC	AACCCAGCAGGTCACGGCCGCCATCAGGGACGGGA
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GCCGCGGCCCTGGCCCGGATCACCGACGAAGTGCT
GTGGCGGTCGTCCTTCGGGGCGACCGAGGATCGCAACACCTTCCGCGTGGGCAGGGGCGGGCAGCGCCGGGCGGGTGGCGGTCGCGCTTCGGGACGACCGAGGATCGCAAC	CAGCGCGGCATCAGCCTCGCGACGCCTGGCCTGGAGGTGGCGGTCGCC
CTTCGAGCTGACCGAGGATCGCAAC	CTGCACCACCGGCTGGTCGGGGAGCTCTACGGCATCGGTGTGGCGGTCGTC
CTTTGGGACGACCGAGGATCGCAAC	CCCGAACCGGGGACCCCCCGTGATGATCAGATTCGGAGTGGCGGTCCCTCGCT
ACGACCGAGGATCGCAACGGCGCGC	TCGTGAAGGAGATGAAGAAGCGCGGGCTGGTGGCGGTTGTCCTTCGGG
ACGACCGAGGATCGTACGTCGGAAT	CGCCTCGCTCCTCGGTCTCGACTGGTCCGGTGGCGGTCGTCCTTCGGGACGA
TCGAGGATCGCAACCCGCTTCCTGCTCGTCGTACAGCTCGGCGGCGCGGGCTTGGCGGTTGCCCTTCAGGACGACCGAGGATCGCAACACCAGCGGCACGACAGGCACGTCGGCCGGCACGCCGGGGTGGCGGTCTCCCTTCGGGGCGACCGAGAATCGCAACACGCTCC	TCCGTCTGGCGGAAGTGGGCGGAGTCGGGGTGGCGG
TCGTCCTTCGGGACGACCGAGGATCGCAACGCCGGAACGC	TCGACAGCCGAGTGCGCCGAGCCCTCGTGGCGGT
CGTCCTTCGGGGCGACCGAGGATCGCAACGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239906.1|8609746_8610253_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NZ_CP024985.1|WP_030239899.1|8612384_8612600_-|DUF397-domain-containing-protein	unknown	unknown	gnl|CDD|377231
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_030239901.1|8611064_8612297_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379262
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	9.19178e-87
NZ_CP024985.1|WP_030239899.1|8612384_8612600_-|DUF397-domain-containing-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.62772e-14
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_030239901.1|8611064_8612297_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	5.96529e-05
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57

Protein sequences

>NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase
MTTLAPQAVVRLGTRPSPMAMEQTGRFAQAFHACHPQLTLDIRKITSEGDAHRGPLSQIGGKGAFTRRADTHLLDGRVDATIACAKDLPGSHDRAPGTAVAAVLPREDVRDVLVLPVGHQPVTLAELPPGTRVGTSAPRRAALLASLFPQLVPVPIRGNADSRLDRLDHGRLGADVMIAALAGLRRLGFADRAGEVLDPTLWLPATGAGIIVVEHRADDTVTGGLLAPLTHPATRILLDAERAVLAELAGGCLTAASAHATLDDTGRVIVRAAVLDPAGGPSVRAEASGSTEHAAEIGRRTARALLNAGALRLLAVTHE
>NZ_CP024985.1|WP_030239899.1|8612384_8612600_-|DUF397-domain-containing-protein
MGDAVPVGVAWQKSAACNGYEDCVEVARLANGNVGVRNSRLPDGPMVQFTSAELAAFLDGVGKGEFDWMTS
>NZ_CP024985.1|WP_030239901.1|8611064_8612297_-|helix-turn-helix-domain-containing-protein
MADRPSHPLARLVDPEGLDRHQSGTTLARRLWGLELREARDNLGWTGAEAVQRGAVSSTTVLSRLEQGKLRAKVTTSVAEALVRAYGVDEVTAVSWRSQAAAIENERSRPGGEVAVVDGDFSASPAFEDILRLERRASEIISFAGVFVPGRVQTRQYSRVVMERACDGRPELLVRVPERLRQRHQRQELLEWGTALHYSMIIDEHVLTTPIPGEAPMLEQLLELQKLARSREWIHLRVLPRSQWAHELPKAMTMSLFRFPAEQAESGEAAAPPAILYLEGSSPEVSRLYTDQARVDQHDANLNMLSNLSLDAEDSLGFIQEQVSRFEAKLRGGAAVRHGCTGAGLSRYAGHSPVLDPAGGGAGLGLGGMTRVPAGHVAGGVLSQHGEAGEEAGDVVAGTDVAPVPTQRVP
>NZ_CP024985.1|WP_030239906.1|8609746_8610253_+|hypothetical-protein
MITAFSGRVPHASPVLEACGTGAAARTGRKDVRAAEQTARTAFKARFDSAYRQYAAVRLGDDDAGDVVEAVWKQIELGWAGLLRCPSPAGGAWTLLSRAVHASPARPPSPLDKLPRPAADAFLLRHCVGLEADRAAEAMGMEPAAFESLYRSVVPRPGSGNPSGIFDR
>NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP

Crispr_ID: NZ_CP024985_29

• CRISPR_ID: NZ_CP024985_29
• CRISPR_location: 8631721-8631831
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_29

Consensus_repeat	Method
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CRISPRCasFinder

spacers of NZ_CP024985_29

>29.1|8631758|36|NZ_CP024985|CRISPRCasFinder
TGCGGTTCTCCACAGACGACGGGGTAGACCTCGCAC

CRISPR arrays and Neighbor proteins around NZ_CP024985_29

CRISPR arrays

The CRISPR arrays of NZ_CP024985_29

>merge|NZ_CP024985|29|8631721-8631831|CRISPRCasFinder
GTGGCGGTCGCTGTTCGGGACGGCCGAGGATCGCAACTGCGGTTCTCCACAGACGACGGGGTAGACCTCGCACGTGGCGGTCGTCCTTCGGGGCGGCCGAGGGTCGCAACC

>NZ_CP024985|29|29|8631721-8631831|CRISPRCasFinder
GTGGCGGTCGCTGTTCGGGACGGCCGAGGATCGCAAC	TGCGGTTCTCCACAGACGACGGGGTAGACCTCGCAC
GTGGCGGTCGTCCTTCGGGGCGGCCGAGGGTCGCAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10

Protein sequences

>NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN

Crispr_ID: NZ_CP024985_31

• CRISPR_ID: NZ_CP024985_31
• CRISPR_location: 8632837-8632948
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_31

Consensus_repeat	Method
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CRISPRCasFinder

spacers of NZ_CP024985_31

>31.1|8632874|38|NZ_CP024985|CRISPRCasFinder
GACGTGGACCTAGGGACACCCGAGCCTGTGGAGCTGAC

CRISPR arrays and Neighbor proteins around NZ_CP024985_31

CRISPR arrays

The CRISPR arrays of NZ_CP024985_31

>merge|NZ_CP024985|31|8632837-8632948|CRISPRCasFinder
GTGGCCGTCGCCCTTCGGGACGACCGAGGATCGCAACGACGTGGACCTAGGGACACCCGAGCCTGTGGAGCTGACGTGGCGGTCGCCCTTCGGGACGGCCGAGGACCGCAAA

>NZ_CP024985|31|31|8632837-8632948|CRISPRCasFinder
GTGGCCGTCGCCCTTCGGGACGACCGAGGATCGCAAC	GACGTGGACCTAGGGACACCCGAGCCTGTGGAGCTGAC
GTGGCGGTCGCCCTTCGGGACGGCCGAGGACCGCAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10

Protein sequences

>NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN

Crispr_ID: NZ_CP024985_28

• CRISPR_ID: NZ_CP024985_28
• CRISPR_location: 8630537-8630712
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_28

Consensus_repeat	Method
GTTGCGATCCTCGGTCACCCTGAAGGGCGACCGCCA	PILER-CR

spacers of NZ_CP024985_28

>28.1|8630573|38|NZ_CP024985|PILER-CR
GGCCGGCCCCACGAGTCGGCCATCATCTGGGCCGATTG
>28.2|8630647|39|NZ_CP024985|PILER-CR
TCCGCCTCGGAAAGGGCGGTCACGACGGTGCCGAGGTCG

CRISPR arrays and Neighbor proteins around NZ_CP024985_28

CRISPR arrays

The CRISPR arrays of NZ_CP024985_28

>merge|NZ_CP024985|28|8630537-8630712|PILER-CR
CCCTTCAAGGTGACTGAGGATCGCAACGGCCGGCCCCACGAGTCGGCCATCATCTGGGCCGATTGTGGCGGTCGCCATTCAGGGTGACCGAGGATCGCAACTCCGCCTCGGAAAGGGCGGTCACGACGGTGCCGAGGTCGTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAAC

>NZ_CP024985|28|14|8630537-8630712|PILER-CR
CCCTTCAAGGTGACTGAGGATCGCAACGGCCGGCCC	CACGAGTCGGCCATCATCTGGGCCGATTGTGGCGGTCG
CCATTCAGGGTGACCGAGGATCGCAACTCCGCCTCG	GAAAGGGCGGTCACGACGGTGCCGAGGTCGTGGCGGTCG
CCCTTCGGGACGACCGAGGATCGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10

Protein sequences

>NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN

Crispr_ID: NZ_CP024985_30

• CRISPR_ID: NZ_CP024985_30
• CRISPR_location: 8632042-8632742
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 9 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_30

Consensus_repeat	Method
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	PILER-CR
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CRISPRCasFinder
GTGGCGGTCGCCCNTCGGGNNGACCGAGGATCGCAAC	CRT
GTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAAC	PILER-CR

spacers of NZ_CP024985_30

>30.1|8632079|38|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
GGCCTCGTCGTTCGTGGTGTTCGCGGCCCTCGCCGCGG
>30.2|8632154|36|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
TGCCTCCGCTTCTGGTGACGGTGCTGGGAGCGCAGC
>30.3|8632227|38|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT
ACCAGGCTCAGGGCCTGCTGTGCCTGGCGACGGCGCGA
>30.4|8632302|36|NZ_CP024985|CRISPRCasFinder,CRT
CTCTTCAAGTGGAAGAAGCTGATCGTCCCCGCCTTC
>30.5|8632375|37|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
TCCCTGGTGGCGGCGGTGACGTCGACTCCCTTGCCGA
>30.6|8632449|38|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
CTCGATGACGTGCTTTTCGAGGGCCCGGCGGACGTCGG
>30.7|8632524|36|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR
CAGAGGAGACCGGCGACGAGCAGAACCAGGACGACC
>30.8|8632597|37|NZ_CP024985|CRISPRCasFinder,CRT
ACCAAGAGCCCCGACCACGCCGCGCGACGGGCTGAAG
>30.9|8632671|34|NZ_CP024985|CRISPRCasFinder,CRT
CGCGAGCGGCTGTGGCAATCCGCGGGTGGTCGGT

CRISPR arrays and Neighbor proteins around NZ_CP024985_30

CRISPR arrays

The CRISPR arrays of NZ_CP024985_30

>merge|NZ_CP024985|30|8632042-8632742|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAACGGCCTCGTCGTTCGTGGTGTTCGCGGCCCTCGCCGCGGGTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAACTGCCTCCGCTTCTGGTGACGGTGCTGGGAGCGCAGCGTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAACACCAGGCTCAGGGCCTGCTGTGCCTGGCGACGGCGCGAGTGGCGGTCGCCCCTCGGGGGGACCGAGGATTGCAACCTCTTCAAGTGGAAGAAGCTGATCGTCCCCGCCTTCGTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAACTCCCTGGTGGCGGCGGTGACGTCGACTCCCTTGCCGAGTGGCGGTCGCCCTTGGGAACGACCGAGGATCGCAACCTCGATGACGTGCTTTTCGAGGGCCCGGCGGACGTCGGGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACCAGAGGAGACCGGCGACGAGCAGAACCAGGACGACCGTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAACACCAAGAGCCCCGACCACGCCGCGCGACGGGCTGAAGGTGGCGGTCGCTCTTCGGGGCGACCGAGGATCGCAACCGCGAGCGGCTGTGGCAATCCGCGGGTGGTCGGTGGTGGCGGCTGCCCTTGGGACGAGCGAGGATCGCAACT

>NZ_CP024985|30|15|8632042-8632301|PILER-CR
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	GGCCTCGTCGTTCGTGGTGTTCGCGGCCCTCGCCGCGG
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	TGCCTCCGCTTCTGGTGACGGTGCTGGGAGCGCAGC
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	ACCAGGCTCAGGGCCTGCTGTGCCTGGCGACGGCGCGA
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATTGCAACCTCTTCAAGTGGAAGAAGCTGATCGTCCCCGCCTTCGTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAAC	TCCCTGGTGGCGGCGGTGACGTCGACTCCCTTGCCGA
GTGGCGGTCGCCCTTGGGAACGACCGAGGATCGCAAC	CTCGATGACGTGCTTTTCGAGGGCCCGGCGGACGTCGG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CAGAGGAGACCGGCGACGAGCAGAACCAGGACGACC


>NZ_CP024985|30|30|8632042-8632742|CRISPRCasFinder
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	GGCCTCGTCGTTCGTGGTGTTCGCGGCCCTCGCCGCGG
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	TGCCTCCGCTTCTGGTGACGGTGCTGGGAGCGCAGC
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	ACCAGGCTCAGGGCCTGCTGTGCCTGGCGACGGCGCGA
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATTGCAAC	CTCTTCAAGTGGAAGAAGCTGATCGTCCCCGCCTTC
GTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAAC	TCCCTGGTGGCGGCGGTGACGTCGACTCCCTTGCCGA
GTGGCGGTCGCCCTTGGGAACGACCGAGGATCGCAAC	CTCGATGACGTGCTTTTCGAGGGCCCGGCGGACGTCGG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CAGAGGAGACCGGCGACGAGCAGAACCAGGACGACC
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	ACCAAGAGCCCCGACCACGCCGCGCGACGGGCTGAAG
GTGGCGGTCGCTCTTCGGGGCGACCGAGGATCGCAAC	CGCGAGCGGCTGTGGCAATCCGCGGGTGGTCGGT
GGTGGCGGCTGCCCTTGGGACGAGCGAGGATCGCAACT

>NZ_CP024985|30|8|8632042-8632741|CRT
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	GGCCTCGTCGTTCGTGGTGTTCGCGGCCCTCGCCGCGG
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	TGCCTCCGCTTCTGGTGACGGTGCTGGGAGCGCAGC
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	ACCAGGCTCAGGGCCTGCTGTGCCTGGCGACGGCGCGA
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATTGCAAC	CTCTTCAAGTGGAAGAAGCTGATCGTCCCCGCCTTC
GTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAAC	TCCCTGGTGGCGGCGGTGACGTCGACTCCCTTGCCGA
GTGGCGGTCGCCCTTGGGAACGACCGAGGATCGCAAC	CTCGATGACGTGCTTTTCGAGGGCCCGGCGGACGTCGG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CAGAGGAGACCGGCGACGAGCAGAACCAGGACGACC
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	ACCAAGAGCCCCGACCACGCCGCGCGACGGGCTGAAG
GTGGCGGTCGCTCTTCGGGGCGACCGAGGATCGCAAC	CGCGAGCGGCTGTGGCAATCCGCGGGTGGTCGGT
GGTGGCGGCTGCCCTTGGGACGAGCGAGGATCGCAAC

>NZ_CP024985|30|16|8632338-8632596|PILER-CR
	GGCCTCGTCGTTCGTGGTGTTCGCGGCCCTCGCCGCGG
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	TGCCTCCGCTTCTGGTGACGGTGCTGGGAGCGCAGC
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATCGCAAC	ACCAGGCTCAGGGCCTGCTGTGCCTGGCGACGGCGCGA
GTGGCGGTCGCCCCTCGGGGGGACCGAGGATTGCAACCTCTTCAAGTGGAAGAAGCTGATCGTCCCCGCCTTCGTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAAC	TCCCTGGTGGCGGCGGTGACGTCGACTCCCTTGCCGA
GTGGCGGTCGCCCTTGGGAACGACCGAGGATCGCAAC	CTCGATGACGTGCTTTTCGAGGGCCCGGCGGACGTCGG
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	CAGAGGAGACCGGCGACGAGCAGAACCAGGACGACC
GTGGCGGTCGTCCTTCGGGACGACCGAGGATCGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10

Protein sequences

>NZ_CP024985.1|WP_159038045.1|8630252_8630405_+|hypothetical-protein
MTEDRNYVQYDTRTLPGVRRWPSGATEDRNEADTFSKRGVPLVAAALQGD
>NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN

Crispr_ID: NZ_CP024985_27

• CRISPR_ID: NZ_CP024985_27
• CRISPR_location: 8629226-8630490
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 16 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b

Consensus repeat of NZ_CP024985_27

Consensus_repeat	Method
GCCCTTCGGGATGACCGAGGATCGCAAC	CRISPRCasFinder
CCTTCGGGNNGACCGAGGATCGCAACN	CRT
GTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAAC	PILER-CR
GCCCTTCGGGATGACCGAGGATCGCAAC	CRISPRCasFinder
GGCGGTCGCCCTTCGGGA	PILER-CR

spacers of NZ_CP024985_27

>27.1|8629254|44|NZ_CP024985|CRISPRCasFinder
GACTGGCCGAACGCACAGCGGGCGGCCCGGACCGGGTGGCGGTT
>27.2|8629326|43|NZ_CP024985|CRISPRCasFinder
CTCGGGGTGGGCGGAGATCGCTCCGCGGAGCCGGAATGGCGGT
>27.3|8629397|45|NZ_CP024985|CRISPRCasFinder
CTCGGCACGGACAAGCGCCTGTACTGGACGCACGACGTGGCGGTC
>27.4|8629254|46|NZ_CP024985|CRT
GACTGGCCGAACGCACAGCGGGCGGCCCGGACCGGGTGGCGGTTGC
>27.5|8629326|45|NZ_CP024985|CRT
CTCGGGGTGGGCGGAGATCGCTCCGCGGAGCCGGAATGGCGGTTG
>27.6|8629397|47|NZ_CP024985|CRT
CTCGGCACGGACAAGCGCCTGTACTGGACGCACGACGTGGCGGTCGT
>27.7|8629470|49|NZ_CP024985|CRT
GAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGGGTGGCGGCCGC
>27.8|8629545|48|NZ_CP024985|CRT
ACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTCGTGGTGGTCGT
>27.9|8629619|47|NZ_CP024985|CRT
GACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACGTGGCGGTCGC
>27.10|8629692|46|NZ_CP024985|CRT
CTGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGGTGGCGGTTGC
>27.11|8629764|46|NZ_CP024985|CRT
CCCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGGTGGTGGTCGC
>27.12|8629836|45|NZ_CP024985|CRT
ACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTCGC
>27.13|8629907|46|NZ_CP024985|CRT
GTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTTGC
>27.14|8629979|47|NZ_CP024985|CRT
CGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTCGC
>27.15|8630052|47|NZ_CP024985|CRT
GAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGTGGCGGTCGT
>27.16|8630125|47|NZ_CP024985|CRT
TTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGCGGCGGTCGC
>27.17|8630198|47|NZ_CP024985|CRT
TCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGTGGCGGTTGC
>27.18|8630271|46|NZ_CP024985|CRT
TATGTGCAGTACGACACGCGGACCCTGCCAGGGGTGCGGCGGTGGC
>27.19|8630343|47|NZ_CP024985|CRT
GAGGCGGACACGTTCAGCAAGCGTGGCGTTCCGCTGGTGGCGGCCGC
>27.20|8629470|38|NZ_CP024985|PILER-CR
GAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGG
>27.21|8629545|38|NZ_CP024985|PILER-CR
AACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTC
>27.22|8629620|36|NZ_CP024985|PILER-CR
GACGGACCTAGGGACACCCGAGCCTGTGGAGCTGAC
>27.23|8629693|35|NZ_CP024985|PILER-CR
CTGACAACGGCGCCAACCTTGCCGGGGCCGTCCGG
>27.24|8629765|35|NZ_CP024985|PILER-CR
CCCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTG
>27.25|8629619|45|NZ_CP024985|CRISPRCasFinder
GACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACGTGGCGGTC
>27.26|8629692|44|NZ_CP024985|CRISPRCasFinder
CTGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGGTGGCGGTT
>27.27|8629764|44|NZ_CP024985|CRISPRCasFinder
CCCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGGTGGTGGTC
>27.28|8629836|43|NZ_CP024985|CRISPRCasFinder
ACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTC
>27.29|8629907|44|NZ_CP024985|CRISPRCasFinder
GTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTT
>27.30|8629979|45|NZ_CP024985|CRISPRCasFinder
CGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTC
>27.31|8630052|45|NZ_CP024985|CRISPRCasFinder
GAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGTGGCGGTC
>27.32|8630125|45|NZ_CP024985|CRISPRCasFinder
TTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGCGGCGGTC
>27.33|8630198|45|NZ_CP024985|CRISPRCasFinder
TCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGTGGCGGTT
>27.34|8630271|44|NZ_CP024985|CRISPRCasFinder
TATGTGCAGTACGACACGCGGACCCTGCCAGGGGTGCGGCGGTG
>27.35|8630343|45|NZ_CP024985|CRISPRCasFinder
GAGGCGGACACGTTCAGCAAGCGTGGCGTTCCGCTGGTGGCGGCC
>27.36|8630416|47|NZ_CP024985|CRISPRCasFinder
GACTTGGCCGTCGCGCGCTTGTGGGCGGACTCGTCGGCGTGGCGGTC
>27.37|8630035|55|NZ_CP024985|PILER-CR
CGACCGAGGATCGCAACGAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGT
>27.38|8630108|55|NZ_CP024985|PILER-CR
CGACCGAGGTTCGCAACTTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGC
>27.39|8630181|55|NZ_CP024985|PILER-CR
CGACCGAGGATCGCAACTCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGT

CRISPR arrays and Neighbor proteins around NZ_CP024985_27

CRISPR arrays

The CRISPR arrays of NZ_CP024985_27

>merge|NZ_CP024985|27|8629226-8630490|CRISPRCasFinder,CRT,PILER-CR,CRISPRCasFinder,PILER-CR
GCCCTTCGGGACGACCGAGGATCGCAACGACTGGCCGAACGCACAGCGGGCGGCCCGGACCGGGTGGCGGTTGCCCTTCGGGGTGACCGAGGTTCGCAACCTCGGGGTGGGCGGAGATCGCTCCGCGGAGCCGGAATGGCGGTTGCCATTCGAGTGACCGAGGATCGCAACCTCGGCACGGACAAGCGCCTGTACTGGACGCACGACGTGGCGGTCGTCCGTCGGGACGACCGAGGATCGCAACGAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGGGTGGCGGCCGCCCTTCGGGACGACGAGGATCGCAACAACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTCGTGGTGGTCGTCCTTCGGGACGACCGAGGATCGCAACGACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACGTGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAACCTGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGGTGGCGGTTGCCCTTCGGGATGACCGAGGATCGCAACCCCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGGTGGTGGTCGCCCTTCGGGATGACCGAGGATCGCAACACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTCGCCCTTCGGGGCGACCGAGGATCGCAACGTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTTGCCTTTCGAGGTGACCGAGGATCGCAACCGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTCGCCCTTTGGGACGACCGAGGATCGCAACGAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGTGGCGGTCGTCCTTTGGGACGACCGAGGTTCGCAACTTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGCGGCGGTCGCCCTTCGGGGCGACCGAGGATCGCAACTCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGTGGCGGTTGCCCTTCGGGATGACCGAGGATCGCAACTATGTGCAGTACGACACGCGGACCCTGCCAGGGGTGCGGCGGTGGCCCTCCGGGGCGACCGAGGATCGCAACGAGGCGGACACGTTCAGCAAGCGTGGCGTTCCGCTGGTGGCGGCCGCCCTTCAGGGCGATTGAGGATCGTAACGACTTGGCCGTCGCGCGCTTGTGGGCGGACTCGTCGGCGTGGCGGTCGCCCCGCGGGGCGTCCGTGGATCGCAAC

>NZ_CP024985|27|27|8629226-8629470|CRISPRCasFinder
GCCCTTCGGGACGACCGAGGATCGCAAC	GACTGGCCGAACGCACAGCGGGCGGCCCGGACCGGGTGGCGGTT
GCCCTTCGGGGTGACCGAGGTTCGCAAC	CTCGGGGTGGGCGGAGATCGCTCCGCGGAGCCGGAATGGCGGT
TGCCATTCGAGTGACCGAGGATCGCAAC	CTCGGCACGGACAAGCGCCTGTACTGGACGCACGACGTGGCGGTC
GTCCGTCGGGACGACCGAGGATCGCAACGAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGGGTGGCGGCCGCCCTTCGGGACGACGAGGATCGCAACAACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTCGTGGTGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACGTGGCGGTC
GCCCTTCGGGACGACCGAGGATCGCAAC	CTGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGGTGGCGGTT
GCCCTTCGGGATGACCGAGGATCGCAAC	CCCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGGTGGTGGTC
GCCCTTCGGGATGACCGAGGATCGCAAC	ACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTC
GCCCTTCGGGGCGACCGAGGATCGCAAC	GTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTT
GCCTTTCGAGGTGACCGAGGATCGCAAC	CGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTC
GCCCTTTGGGACGACCGAGGATCGCAAC	GAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGTGGCGGTC
GTCCTTTGGGACGACCGAGGTTCGCAAC	TTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGCGGCGGTC
GCCCTTCGGGGCGACCGAGGATCGCAAC	TCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGTGGCGGTT
GCCCTTCGGGATGACCGAGGATCGCAAC	TATGTGCAGTACGACACGCGGACCCTGCCAGGGGTGCGGCGGTG
GCCCTCCGGGGCGACCGAGGATCGCAAC	GAGGCGGACACGTTCAGCAAGCGTGGCGTTCCGCTGGTGGCGGCC
GCCCTTCAGGGCGATTGAGGATCGTAAC	GACTTGGCCGTCGCGCGCTTGTGGGCGGACTCGTCGGCGTGGCGGTC


>NZ_CP024985|27|7|8629228-8630415|CRT
CCTTCGGGACGACCGAGGATCGCAAC	GACTGGCCGAACGCACAGCGGGCGGCCCGGACCGGGTGGCGGTTGC
CCTTCGGGGTGACCGAGGTTCGCAAC	CTCGGGGTGGGCGGAGATCGCTCCGCGGAGCCGGAATGGCGGTTG
CCATTCGAGTGACCGAGGATCGCAAC	CTCGGCACGGACAAGCGCCTGTACTGGACGCACGACGTGGCGGTCGT
CCGTCGGGACGACCGAGGATCGCAAC	GAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGGGTGGCGGCCGC
CCTTCGGGACGACGAGGATCGCAACA	ACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTCGTGGTGGTCGT
CCTTCGGGACGACCGAGGATCGCAAC	GACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACGTGGCGGTCGC
CCTTCGGGACGACCGAGGATCGCAAC	CTGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGGTGGCGGTTGC
CCTTCGGGATGACCGAGGATCGCAAC	CCCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGGTGGTGGTCGC
CCTTCGGGATGACCGAGGATCGCAAC	ACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTCGC
CCTTCGGGGCGACCGAGGATCGCAAC	GTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTTGC
CTTTCGAGGTGACCGAGGATCGCAAC	CGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTCGC
CCTTTGGGACGACCGAGGATCGCAAC	GAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGTGGCGGTCGT
CCTTTGGGACGACCGAGGTTCGCAAC	TTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGCGGCGGTCGC
CCTTCGGGGCGACCGAGGATCGCAAC	TCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGTGGCGGTTGC
CCTTCGGGATGACCGAGGATCGCAAC	TATGTGCAGTACGACACGCGGACCCTGCCAGGGGTGCGGCGGTGGC
CCTCCGGGGCGACCGAGGATCGCAAC	GAGGCGGACACGTTCAGCAAGCGTGGCGTTCCGCTGGTGGCGGCCGC
CCTTCAGGGCGATTGAGGATCGTAAC

>NZ_CP024985|27|12|8629433-8629835|PILER-CR
GTGGCGGTCGTCCGTCGGGACGACCGAGGATCGCAAC	GAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGG
GTGGCGGCCGCCCTTCGGGACGACGAGGATCGCAACA	ACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTCG
TGGTGGTCGTCCTTCGGGACGACCGAGGATCGCAACG	ACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACG
TGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAACC	TGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGG
TGGCGGTTGCCCTTCGGGATGACCGAGGATCGCAACC	CCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGG
TGGTGGTCGCCCTTCGGGATGACCGAGGATCGCAACACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTCGCCCTTCGGGGCGACCGAGGATCGCAACGTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTTGCCTTTCGAGGTGACCGAGGATCGCAACCGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTCGCCCTTTGGGA	CGACCGAGGATCGCAACGAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGT
GGCGGTCGTCCTTTGGGA	CGACCGAGGTTCGCAACTTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGC
GGCGGTCGCCCTTCGGGG	CGACCGAGGATCGCAACTCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGT


>NZ_CP024985|27|28|8629591-8630490|CRISPRCasFinder
	GACTGGCCGAACGCACAGCGGGCGGCCCGGACCGGGTGGCGGTT
GCCCTTCGGGGTGACCGAGGTTCGCAAC	CTCGGGGTGGGCGGAGATCGCTCCGCGGAGCCGGAATGGCGGT
TGCCATTCGAGTGACCGAGGATCGCAAC	CTCGGCACGGACAAGCGCCTGTACTGGACGCACGACGTGGCGGTC
GTCCGTCGGGACGACCGAGGATCGCAACGAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGGGTGGCGGCCGCCCTTCGGGACGACGAGGATCGCAACAACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTCGTGGTGGTCGTCCTTCGGGACGACCGAGGATCGCAAC	GACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACGTGGCGGTC
GCCCTTCGGGACGACCGAGGATCGCAAC	CTGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGGTGGCGGTT
GCCCTTCGGGATGACCGAGGATCGCAAC	CCCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGGTGGTGGTC
GCCCTTCGGGATGACCGAGGATCGCAAC	ACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTC
GCCCTTCGGGGCGACCGAGGATCGCAAC	GTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTT
GCCTTTCGAGGTGACCGAGGATCGCAAC	CGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTC
GCCCTTTGGGACGACCGAGGATCGCAAC	GAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGTGGCGGTC
GTCCTTTGGGACGACCGAGGTTCGCAAC	TTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGCGGCGGTC
GCCCTTCGGGGCGACCGAGGATCGCAAC	TCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGTGGCGGTT
GCCCTTCGGGATGACCGAGGATCGCAAC	TATGTGCAGTACGACACGCGGACCCTGCCAGGGGTGCGGCGGTG
GCCCTCCGGGGCGACCGAGGATCGCAAC	GAGGCGGACACGTTCAGCAAGCGTGGCGTTCCGCTGGTGGCGGCC
GCCCTTCAGGGCGATTGAGGATCGTAAC	GACTTGGCCGTCGCGCGCTTGTGGGCGGACTCGTCGGCGTGGCGGTC
GCCCCGCGGGGCGTCCGTGGATCGCAAC

>NZ_CP024985|27|13|8630017-8630253|PILER-CR
	GAGTCGATGGGGTTGCCCCGGTACGTCGTCAGCAAGGG
GTGGCGGCCGCCCTTCGGGACGACGAGGATCGCAACA	ACCGTCACCCGCGGCTGACGGTCCCCCTTGTCGGGTCG
TGGTGGTCGTCCTTCGGGACGACCGAGGATCGCAACG	ACGGACCTAGGGACACCCGAGCCTGTGGAGCTGACG
TGGCGGTCGCCCTTCGGGACGACCGAGGATCGCAACC	TGACAACGGCGCCAACCTTGCCGGGGCCGTCCGGG
TGGCGGTTGCCCTTCGGGATGACCGAGGATCGCAACC	CCACAGTGGGAAGCGACAGGCGCCGGGGAAGCTGG
TGGTGGTCGCCCTTCGGGATGACCGAGGATCGCAACACCAAGTGGGAGGACGAGGAGACTACCAACACGAGTGGCGGTCGCCCTTCGGGGCGACCGAGGATCGCAACGTCGGGTGCTGTACCCGCCCGATCGAGCGCACCGGGTTGCGGTTGCCTTTCGAGGTGACCGAGGATCGCAACCGCACGGACCGGCTTGAGAATGACTCCGGCCAGCTCGTGGCGGTCGCCCTTTGGGA	CGACCGAGGATCGCAACGAGGGTGTCCTCTTCGATCGGGACCCGCGCGCGGGCGT
GGCGGTCGTCCTTTGGGA	CGACCGAGGTTCGCAACTTCACCGGGTACTCGATCGTCTCACCGGAACCCGTGGC
GGCGGTCGCCCTTCGGGG	CGACCGAGGATCGCAACTCCTCCACCCACGCGCGGCCGACGAGTGCGTGCGTCGT
GGCGGTTGCCCTTCGGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|236880
NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|187782
NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	unknown	unknown	gnl|CDD|234948
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	unknown	unknown	gnl|CDD|379241
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl|CDD|378245
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	unknown	unknown	gnl|CDD|319911
NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	2.1e-50	166.4	0.0
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	1e-66	219.3	0.0
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	8.9e-92	303.1	0.0
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	1.3e-80	265.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	4.40765e-113
NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	9.19178e-87
NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.5125e-11
NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	2.46756e-76
NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	7.81832e-06
NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87891e-33
NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.00673e-05
NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	5.09224e-108
NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	4.72772e-10
NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.24718e-57
NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.91805e-35
NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	4.70733e-57
NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	8.8838e-10

Protein sequences

>NZ_CP024985.1|WP_030239879.1|8628673_8629072_-|hypothetical-protein
MRVLFFPDEDGVDVSGGAAELAVLAFALAAGKGGTETTASAEPSFGGTELASVEVVSTSGPGVRIRVDSERSALLIEGDRLGLTALADEVQSIAEMDDGGHQHIEYFPDHYYLVAGSLAMVVNSPHGGMPTR
>NZ_CP024985.1|WP_100660728.1|8627467_8628724_+|IS110-family-transposase
MIDTSDIDVFLGLDVGKGEHHATAVTPAGKKAFDKRLPNTEPKLRELFAKLQAKHGTVLVVVDQPASIGALPLAVARNMGCPIAYLPGLTMRRIADLYPGEAKTDAKDAFIIADAARAMPHTLRAVDGEDETIAELEMIVGSDDDLAGEATRVANRLHGLLTQIHPSLERVLGPRLQHPAVLMLLERFGSPAQIRKAGRRRLVTLLRPKAPRMAERLVEEIFAALDEQTVTVPGTEAAALIVPSLAGSLTAVLGQRKLLAGRIEELLEAHPLSKVLTSMPGVGVRTGARILIEVGDGSTFPTAGHLAAYAGLAPATRSSGSSIRGEQPSRRGNKQLKRAFFLSAFAALGDPASRAYYDKKISQGKHHTQALLCLARRRADVLFAMLRDGTFYEPRPATAISRSSSRHAAMRTVYDHGQ
>NZ_CP024985.1|WP_158740930.1|8625768_8626083_+|hypothetical-protein
MAVAIRVTEDRNIDASKLGADTAVGAVAFRDDRGSQLHGGADSGAHAVEWRSPFGTTKDRNQTRPVEPRPSAARRSPFGATEDRNDHDQAAEQQRAAGGSCPSG
>NZ_CP024985.1|WP_078950658.1|8621625_8623899_-|CRISPR-associated-endonuclease-Cas3''
MSSLSVEPGDSEDPGEPLWAHSRSDVSGLRHTVQDHLRGSASLACVFGGAFGMGPSAEYLALVHDVGKGSCAWQVALERAERLGGRVGVPHKGAGALLAAEVLGRPFAAPVLGHHGGMPSLQELGAVLAELAGTGVEGQAAREATVRVAGVVPEILRSGRIPPPPWLTDLQIPARELRLRMDLLVRMLFSCLVDADFLDTEAHFAGRPVRLSRLADLAVLAARFEARRHEMLARREKSPVDEVRGAVYEQALAAAAGPPGMYVLHVPTGGGKTLSAGGFALHHAAAYGMRRVVVVVPFISITQQNAQVYRDMLDPRSEAEGEPVVLEHHSSVELDDEGNGVWSRLAAENWDAPFVVTTTVQLFQSLFDRKPSAMRKLHRLAGSVIVLDEVQALPDRLLLPILSVLRGLVEHFGVSVVLVSATQPEFWSMPRLEGLERRGVVSDVARLFRELHRVRYEWRMDVGVTWESIAEEIADAGEQVLAIVNTTRDAALLHRMLTERCEGRVRHLSTRMTAGHRQEGITSIRKDLKEGLPVRVVSTSLIEAGVDVDFPWVYRAWAPAESLQQAAGRCNRDGRLPEGVTVVFRAQDGGQPKDPSYTAALEATSEFFGPGLAFPDDLDALASYYRQRYAYQVVGGEGMGSHIEASRQALDFPQVAKDFQMIADQYSQPVVVVRCEEDRAAMEADVAALRRPYPCGPEVLRRLQPHMAALPRHEVHAALSCGLAEPVVGDLVLWCGSYDEERGLDPFEPEDRAGYLF
>NZ_CP024985.1|WP_037688829.1|8620492_8621185_-|type-I-C-CRISPR-associated-protein-Cas5
MFPDLVVETWGELACFTRPELKAERVSYPVMTPSAARGLLEAIFWKPEFSYVITKIEVLSPIQWVQVRRNEVKSTINAATVRDLRADSSRRYDVEADRDQRSTMALQDVRYRIGAQVVTAAHAGAPQEKFREQLRRRVERGASFSQPFFGCREFTAFFGPADSSKAVGPIARTEELGVMLHSIAYTPQGERYRWFRASLVDGVLNVPLQPLPDDAVAMPQAPWRATGAGA
>NZ_CP024985.1|WP_078950659.1|8618718_8620488_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MLLARLTEYSEQLGGSLPPEFYRPKQIHWILHVKEDGSGAGLVSRRPPPKARDQALITPVPYVQRSGTKVPPYLLVDTAEFVLGRAKNATHPDGPSPKDEEEAQRRHAAYRDLALRWAQGEPDNPSAIALRAFLAAGGLPKQQHPEDLDAKDTVAIMVGTHWLHEDPSVQRVWSQVARERKGGAGQRGLCLICGTLGDLLATIPEPVKKGAIPTTGGSNEGQLISINTSAQGRDGATQLANTPVCDRCGQQAMSTLNHLLASDTNRRRFPDSVMVWWTRTSADDSPMALLYQDQPDPAAVSHLIEAFRQRPSSAAADRVDPNDFYALTLGLNNARIVVREWLEVPLEDLKVNVGAWYLDHGVHDGWTGQSRYVPLWLLALSAGRHDGDRYVKDSAPHGLEADLARCALRRTPPPARLLPSLLQRIRADHHIDAPRVALLRLILNRSADPKDHLMPTLDLSSGDPAYLCGRAFAVLEAVQRTAMRDVNTTIRDKHFSAAVTAPGVVLTQLRIGANAHLKRLRRDRPAAGSALESRLSEVFSAFRDDIPLHLTPREQGRFVIGYEQQRAADRAAAKSHSTPGKSTDPDPEP
>NZ_CP024985.1|WP_030239890.1|8617756_8618653_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTQAHLDPTRKHDFVFLIDATDSNPNGDPDNGGIPRTDPVTGQGLITDVAIKRKIRNTIALINRTENKPGYEIYVEAGVALNAQHERAYTPESGATNQSEARAWMCRNFFDVRMFGAVMSTGKKDKQAGRVQGPMQISFSRSIDPITPFDIGVTRVTPTKQEDIDAWHNPEEGKKGKETEMGSKHIVPYGLYRGAGHFSAPLAAKTGVTSDDLAAFWRAFTLMLDHDRAAARGALALRGLYVFTHDDAFGRAPAHTLLDRIHIKPLGDVSARSFTDYGTVEIRDTDLPAGITLTRVIG
>NZ_CP024985.1|WP_030239892.1|8617242_8617659_-|hypothetical-protein
MPRALRAAVAQAEVVAGLEVASHLQAGPVWDAFLAVRREELMPQAYVRRSGPEETPPRWDLLGWSAPAHQEKLLGLLYSREGSVPVQHRGELVPAVHRGRDRAGRCLPYPARLACPSRSSNAWACCQAFQWPGTPPHA
>NZ_CP024985.1|WP_030239895.1|8616379_8616928_-|AAA-family-ATPase
MIIWINGAFGAGKSTLDAGLREALPGSVVADPEDVGSLLRSSMRGHPHAVRNYQEYPAWRRLTVRLVTELHHLAGGTVIVPMTVLHQPYARDMLEPLAALGVPVHHLGLHTDPSPLRARIDASLEYPHDEARSEAVRAHRRRGINDYEQAFKAWLNTARVIDTGSLTPGQVLEAALAQLART
>NZ_CP024985.1|WP_030239897.1|8615399_8616359_-|hydroxymethylbilane-synthase
MTTLAPQAVVRLGTRPSPMAMEQTGRFAQAFHACHPQLTLDIRKITSEGDAHRGPLSQIGGKGAFTRRADTHLLDGRVDATIACAKDLPGSHDRAPGTAVAAVLPREDVRDVLVLPVGHQPVTLAELPPGTRVGTSAPRRAALLASLFPQLVPVPIRGNADSRLDRLDHGRLGADVMIAALAGLRRLGFADRAGEVLDPTLWLPATGAGIIVVEHRADDTVTGGLLAPLTHPATRILLDAERAVLAELAGGCLTAASAHATLDDTGRVIVRAAVLDPAGGPSVRAEASGSTEHAAEIGRRTARALLNAGALRLLAVTHE
>NZ_CP024985.1|WP_030239875.1|8634431_8634773_-|glyoxalase
MAIDSVVVRQRVEDLDAAVPFYEKLTGSTASRFAFAGVTLASVGPFLLFAGPDEAVQRVAGVAATLTVADLDAAVDEAGAGGAEIVMPIQTTPNGRRAVLRHPHGGVFEYVGP
>NZ_CP024985.1|WP_030239872.1|8636498_8637122_-|hypothetical-protein
MTTATTHHVPYFSQWESASLVPEFVSGTTAAAADPLWASSGADTAEEYAFWAPRMCGMACLRMALGYFGHPVPASVPLVREALAAGAYVRDGDQVQGLIYAPFAAWVATRWGLFAESRPQLSVEQVDAEVARGRLVLLSVHRSIRTLDLEPAQRGGHLVLAVGSNANHIAIHNPSGFPEISQQFHQVPRADLGRFFAGRGVVLGHAQ
>NZ_CP024985.1|WP_158740928.1|8637140_8637494_-|hypothetical-protein
MLPLLACETDRAFYDYEAKHDQGLRRETCPAALPEDVEQRVMETALRVHRLIGAHGVSRVDFLVCSDGRSLVLEVNTVPGLSEHGNLATMAAAAGVSYVELIKRVLDTAFTKVSYVP
>NZ_CP024985.1|WP_037688867.1|8638037_8638742_-|HNH-endonuclease
MFRGLPALALCALPILAAPTAHSATAETAPLAATGVTGPAGVRAPLPLFEAIDRLPVAAEHRDGYKRDLYKHWNRGLNATDGCDTRKEVILAEAVTAPQVAAGCKLTSGSWLSAYDNVVVSDAARLDVDHFVPLAEVYDSERAPWSAARREAYANDQASPDTLIAVSAASNRSKADKDPAEWLPSDDSYHCTYAASWVGTKLRWDLAVDESERHALLGLAEDCPATTVVYESAP
>NZ_CP024985.1|WP_030239868.1|8638833_8639052_-|hypothetical-protein
MITIEIRGHEKAVLEAAHRISALFLSSGPCQLRRTPGENEVQVLVHADISRGTGDSGYLDPDEAESAGSFLR
>NZ_CP024985.1|WP_158740926.1|8639463_8639979_-|hypothetical-protein
MALVRPSTDCPDPMCEDGITLHLGHPCPKCTERRADRRRGRVPAQRNNGPTLQWWECQGNDCSAAGRGRPPEGSLCQHCQAREEHKKIQNATAHLLAETQTAQEAERLRHSIRWERMLNDAYTQHAEYTRTEQNQEETKQRAAATAAETHRLRQQILRQHPELAPYTQHQP
>NZ_CP024985.1|WP_158740924.1|8641263_8642025_-|GntR-family-transcriptional-regulator
MPLQQWRELADRLAERIESGEFPPGSKMPTTVELMAEGESKPSIERAYRELVDRGLVVRKPRVGTVVRSRSRVRIPLSRYGLVLQPGGDKGPWETATAAVGLGGSIAAVSVERLPAPDTIAVLLGLEPGAPVVRRSRHALIDGDVVQVQEAFYPAELADATGLGEPGRIAGGVLRAMTASGLAPETASETVTARLPTKAEASELGIGARVPVLCIERVVHDRDGRALEALRTVGAADRLELHYGNLPMTGGIP
>NZ_CP024985.1|WP_030239864.1|8642384_8642819_+|hypothetical-protein
MEFVLRIDVDGALVVLPWPDDEVARGAQVRGAVGGPADRAVYHRQAHLHVHGNGAAEGLPVNLAAWVLASQWRGVEIPYGFYGPVLVTGPEWSALGDGVAGEVRAVCAAVAEVRQEWVTRPPAGEGPARAEMLAAARHSVAALA
>NZ_CP024985.1|WP_158740922.1|8642937_8643354_-|hypothetical-protein
MRVTLTGVAYRDALAKDKTLPLTGKYALAVALTLESENGGTFKGYGKDNLIKWSYGPEMNKASRYYDAPWDGCIDSYTPWGKVAAGQPYLAISSMNISRRGGNLLMEDSYGSIARWDLPQEDTGTGTEPATKYATTDC
>NZ_CP024985.1|WP_100660726.1|8643703_8647105_-|LysM-peptidoglycan-binding-domain-containing-protein
MSQPTPGRPSRPRLGRGGAQTAAALVRGLLSLAVLAALLAGLPILLWWATAQVGPPGITALANLLTTDDSGQVFLLLLAVTGWISWAQFALAVLLEIPAQLRGRSAPQIRGLVGQRAAAALVGAVLLALPAGTALAAPTSPAAAAPVSVSATAVPGPDTAASARANTGAVQEAGTGLVTHTVRDVRPAESLWSIAETTLGDAHRWEEIAALNEGHSMTDGAVFRADQPIQPGWVLTLPSDAHPAPSAGLKTQAGRGNAAEALSGQAQYSVREGDSLSFISRVQLGDADRYPEIFEQNKGTPLPDGARTFTDPNLIYPGQQLTLPAASTPSPSPRTMPPSQARPGNDTTTPAAKPSPAAPAPAAPTAKPTPAPTAPPVPSSPTAPAAVSPSPSASTAQSAPAATTPAAQVPQQSTPPAANSPAASPLQASPAVSTPQVLAAANGVNWALIAGIGTLLAASLAGALGVRRILQQRARRAGETIAQDNDPTTVEQVLHAVAEPAGVELLDHVLRALAHYAATDNESSNSNKALPALRGARLAANGITLLLDEPADPIAPFTAGSDTRTWVLDEQAVLPGADDLADVHAPYPGLVTLGADGDGLVLADLTTCRVLLLNGDADEVLEVARALALELGTSGWTDYAEILTAGLGSRLSGLLPQGRIRTMAHLPAVAADLGELLLEAHQSGEQVLPWLMIGAGDHSENDVDLLADALASARPLTTAVVLPASPEARRAFPHAEILDVARDQDTVLAPLETPVRLQRVSDEQYRQYVHALQVSVQEAKPAAGAWEFTESHQQPAASGMPLAVRITSEAAQDPGNPFPALLAGFNPTPTSPATQAPEAGADTTQEHDIDQAPATRAAGQAPLPHQANGSQPAPAPKASPTSTSPVERTVRIDMLGALRITGGTGSAHAPRTTAVAALIHLRPGRSAEYLCRAVDPVKPWSTRTLHSRLSELRAEIGVATDGAPLLPRPKDGGYSFHRAVTSDWEEFRALASSGLAAGPKAGITDLEAAMALVRGKPFDGRTLPWADAVIQEMLSRITDTAHTLACWHTDSDTPDLDAARRTVLQALDVEETSEVLYRDLLTIDRAAGNTSAVRKTVARIQQMARTYDITLDDITEDTINHALSTAPPHLTNN

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP024985_4	4.1|61177|45|NZ_CP024985|CRISPRCasFinder	61177-61221	45	NZ_CP024985.1	8630491-8630535	0	1.0
NZ_CP024985_5	5.1|65139|38|NZ_CP024985|CRISPRCasFinder	65139-65176	38	NZ_CP024985.1	8626536-8626573	0	1.0
NZ_CP024985_28	28.1|8630573|38|NZ_CP024985|PILER-CR	8630573-8630610	38	NZ_CP024985.1	61111-61148	0	1.0
NZ_CP024985_28	28.2|8630647|39|NZ_CP024985|PILER-CR	8630647-8630685	39	NZ_CP024985.1	61036-61074	0	1.0
NZ_CP024985_17	17.2|4076706|18|NZ_CP024985|CRISPRCasFinder	4076706-4076723	18	NZ_CP024985.1	673918-673935	1	0.944
NZ_CP024985_17	17.2|4076706|18|NZ_CP024985|CRISPRCasFinder	4076706-4076723	18	NZ_CP024985.1	988792-988809	1	0.944
NZ_CP024985_17	17.2|4076706|18|NZ_CP024985|CRISPRCasFinder	4076706-4076723	18	NZ_CP024985.1	2420119-2420136	1	0.944
NZ_CP024985_17	17.2|4076706|18|NZ_CP024985|CRISPRCasFinder	4076706-4076723	18	NZ_CP024985.1	2910168-2910185	1	0.944
NZ_CP024985_17	17.2|4076706|18|NZ_CP024985|CRISPRCasFinder	4076706-4076723	18	NZ_CP024985.1	5863068-5863085	1	0.944
NZ_CP024985_17	17.2|4076706|18|NZ_CP024985|CRISPRCasFinder	4076706-4076723	18	NZ_CP024985.1	7792567-7792584	1	0.944
NZ_CP024985_4	4.17|62344|43|NZ_CP024985|CRT,CRISPRCasFinder	62344-62386	43	NZ_CP024985.1	65936-65978	2	0.953
NZ_CP024985_4	4.17|62344|43|NZ_CP024985|CRT,CRISPRCasFinder	62344-62386	43	NZ_CP024985.1	8625734-8625776	2	0.953
NZ_CP024985_7	7.1|990822|19|NZ_CP024985|CRISPRCasFinder	990822-990840	19	NZ_CP024985.1	7067762-7067780	2	0.895
NZ_CP024985_7	7.1|990822|19|NZ_CP024985|CRISPRCasFinder	990822-990840	19	NZ_CP024985.1	8129090-8129108	2	0.895
NZ_CP024985_23	23.4|5646431|21|NZ_CP024985|CRT	5646431-5646451	21	NZ_CP024985.1	6960695-6960715	2	0.905
NZ_CP024985_27	27.2|8629326|43|NZ_CP024985|CRISPRCasFinder	8629326-8629368	43	NZ_CP024985.1	65936-65978	2	0.953
NZ_CP024985_27	27.2|8629326|43|NZ_CP024985|CRISPRCasFinder	8629326-8629368	43	NZ_CP024985.1	8625734-8625776	2	0.953
NZ_CP024985_27	27.5|8629326|45|NZ_CP024985|CRT	8629326-8629370	45	NZ_CP024985.1	65934-65978	2	0.956
NZ_CP024985_27	27.5|8629326|45|NZ_CP024985|CRT	8629326-8629370	45	NZ_CP024985.1	8625734-8625778	2	0.956

1. spacer 4.1|61177|45|NZ_CP024985|CRISPRCasFinder matches to position: 8630491-8630535, mismatch: 0, identity: 1.0

aaccgccatccgccacggggccgcccgctgtacgttcggccagtc	CRISPR spacer
aaccgccatccgccacggggccgcccgctgtacgttcggccagtc	Protospacer
*********************************************

2. spacer 5.1|65139|38|NZ_CP024985|CRISPRCasFinder matches to position: 8626536-8626573, mismatch: 0, identity: 1.0

caccgcccctgccagggcggatcaccttggttcccgaa	CRISPR spacer
caccgcccctgccagggcggatcaccttggttcccgaa	Protospacer
**************************************

3. spacer 28.1|8630573|38|NZ_CP024985|PILER-CR matches to position: 61111-61148, mismatch: 0, identity: 1.0

ggccggccccacgagtcggccatcatctgggccgattg	CRISPR spacer
ggccggccccacgagtcggccatcatctgggccgattg	Protospacer
**************************************

4. spacer 28.2|8630647|39|NZ_CP024985|PILER-CR matches to position: 61036-61074, mismatch: 0, identity: 1.0

tccgcctcggaaagggcggtcacgacggtgccgaggtcg	CRISPR spacer
tccgcctcggaaagggcggtcacgacggtgccgaggtcg	Protospacer
***************************************

5. spacer 17.2|4076706|18|NZ_CP024985|CRISPRCasFinder matches to position: 673918-673935, mismatch: 1, identity: 0.944

ggcggcggcctccgtcac	CRISPR spacer
ggcggcggcctccatcac	Protospacer
*************.****

6. spacer 17.2|4076706|18|NZ_CP024985|CRISPRCasFinder matches to position: 988792-988809, mismatch: 1, identity: 0.944

ggcggcggcctccgtcac	CRISPR spacer
ggcggcggcccccgtcac	Protospacer
**********.*******

7. spacer 17.2|4076706|18|NZ_CP024985|CRISPRCasFinder matches to position: 2420119-2420136, mismatch: 1, identity: 0.944

ggcggcggcctccgtcac	CRISPR spacer
ggcggccgcctccgtcac	Protospacer
****** ***********

8. spacer 17.2|4076706|18|NZ_CP024985|CRISPRCasFinder matches to position: 2910168-2910185, mismatch: 1, identity: 0.944

ggcggcggcctccgtcac	CRISPR spacer
ggtggcggcctccgtcac	Protospacer
**.***************

9. spacer 17.2|4076706|18|NZ_CP024985|CRISPRCasFinder matches to position: 5863068-5863085, mismatch: 1, identity: 0.944

ggcggcggcctccgtcac	CRISPR spacer
ggcggcggcctccgtgac	Protospacer
*************** **

10. spacer 17.2|4076706|18|NZ_CP024985|CRISPRCasFinder matches to position: 7792567-7792584, mismatch: 1, identity: 0.944

ggcggcggcctccgtcac	CRISPR spacer
ggcggcggccgccgtcac	Protospacer
********** *******

11. spacer 4.17|62344|43|NZ_CP024985|CRT,CRISPRCasFinder matches to position: 65936-65978, mismatch: 2, identity: 0.953

accgccattccggctccgcggagcgatctccgcccaccccgag	CRISPR spacer
accgccatgccggctccgcagagcgatctccgcccaccccgag	Protospacer
******** **********.***********************

12. spacer 4.17|62344|43|NZ_CP024985|CRT,CRISPRCasFinder matches to position: 8625734-8625776, mismatch: 2, identity: 0.953

accgccattccggctccgcggagcgatctccgcccaccccgag	CRISPR spacer
accgccatgccggctccgcagagcgatctccgcccaccccgag	Protospacer
******** **********.***********************

13. spacer 7.1|990822|19|NZ_CP024985|CRISPRCasFinder matches to position: 7067762-7067780, mismatch: 2, identity: 0.895

ccccgacgcgaacgcgggg	CRISPR spacer
ccccggcgcgatcgcgggg	Protospacer
*****.***** *******

14. spacer 7.1|990822|19|NZ_CP024985|CRISPRCasFinder matches to position: 8129090-8129108, mismatch: 2, identity: 0.895

ccccgacgcgaacgcgggg	CRISPR spacer
cctcgacgagaacgcgggg	Protospacer
**.***** **********

15. spacer 23.4|5646431|21|NZ_CP024985|CRT matches to position: 6960695-6960715, mismatch: 2, identity: 0.905

cggccggagccgctgcgcgga	CRISPR spacer
cggccggagcccccgcgcgga	Protospacer
*********** *.*******

16. spacer 27.2|8629326|43|NZ_CP024985|CRISPRCasFinder matches to position: 65936-65978, mismatch: 2, identity: 0.953

ctcggggtgggcggagatcgctccgcggagccggaatggcggt	CRISPR spacer
ctcggggtgggcggagatcgctctgcggagccggcatggcggt	Protospacer
***********************.********** ********

17. spacer 27.2|8629326|43|NZ_CP024985|CRISPRCasFinder matches to position: 8625734-8625776, mismatch: 2, identity: 0.953

ctcggggtgggcggagatcgctccgcggagccggaatggcggt	CRISPR spacer
ctcggggtgggcggagatcgctctgcggagccggcatggcggt	Protospacer
***********************.********** ********

18. spacer 27.5|8629326|45|NZ_CP024985|CRT matches to position: 65934-65978, mismatch: 2, identity: 0.956

ctcggggtgggcggagatcgctccgcggagccggaatggcggttg	CRISPR spacer
ctcggggtgggcggagatcgctctgcggagccggcatggcggttg	Protospacer
***********************.********** **********

19. spacer 27.5|8629326|45|NZ_CP024985|CRT matches to position: 8625734-8625778, mismatch: 2, identity: 0.956

ctcggggtgggcggagatcgctccgcggagccggaatggcggttg	CRISPR spacer
ctcggggtgggcggagatcgctctgcggagccggcatggcggttg	Protospacer
***********************.********** **********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP024985_2	2.5|59301|37|NZ_CP024985|CRISPRCasFinder,PILER-CR	59301-59337	37	NC_004931	Streptomyces sp. EN27 plasmid pEN2701, complete sequence	9774-9810	2	0.946
NZ_CP024985_30	30.5|8632375|37|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR	8632375-8632411	37	NC_004931	Streptomyces sp. EN27 plasmid pEN2701, complete sequence	9774-9810	2	0.946
NZ_CP024985_4	4.19|61480|34|NZ_CP024985|PILER-CR	61480-61513	34	MT639641	Microbacterium phage Phinky, complete genome	38896-38929	4	0.882
NZ_CP024985_6	6.21|67478|36|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR	67478-67513	36	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	91152-91187	4	0.889
NZ_CP024985_16	16.1|4022375|25|NZ_CP024985|CRISPRCasFinder	4022375-4022399	25	NC_015951	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence	46956-46980	4	0.84
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1529748-1529774	4	0.852
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1529884-1529910	4	0.852
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	MT657335	Gordonia phage Mariokart, complete genome	7276-7302	4	0.852
NZ_CP024985_25	25.2|8624199|36|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624199-8624234	36	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	91152-91187	4	0.889
NZ_CP024985_4	4.19|61480|34|NZ_CP024985|PILER-CR	61480-61513	34	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	80051-80084	5	0.853
NZ_CP024985_5	5.3|65286|33|NZ_CP024985|CRISPRCasFinder	65286-65318	33	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	280960-280992	5	0.848
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP035511	Haematobacter massiliensis strain OT1 plasmid pOT1-1, complete sequence	243712-243738	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	157608-157634	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP020613	Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence	35862-35888	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	424943-424969	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP029211	Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence	122918-122944	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	481706-481732	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	MT711975	Streptomyces phage Alderaan, complete genome	14877-14903	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	MH825706	Streptomyces phage Microdon, complete genome	43701-43727	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4775105-4775131	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	180627-180653	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	394110-394136	5	0.815
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	MT521991	Streptomyces phage Eklok, complete genome	26949-26975	5	0.815
NZ_CP024985_20	20.1|5130922|28|NZ_CP024985|CRISPRCasFinder	5130922-5130949	28	NZ_CP034431	Bradyrhizobium sp. LCT2 plasmid pLCT2, complete sequence	162947-162974	5	0.821
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	753724-753753	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1393816-1393845	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1345166-1345195	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1089184-1089213	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1345173-1345202	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1592643-1592672	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1592585-1592614	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1271074-1271103	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1080191-1080220	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1217124-1217153	5	0.833
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	633889-633918	5	0.833
NZ_CP024985_26	26.8|8626394|33|NZ_CP024985|CRISPRCasFinder	8626394-8626426	33	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	280960-280992	5	0.848
NZ_CP024985_4	4.19|61480|34|NZ_CP024985|PILER-CR	61480-61513	34	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	323068-323101	6	0.824
NZ_CP024985_6	6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT	67042-67076	35	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	236716-236750	6	0.829
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	MT889376	Arthrobacter phage Phives, complete genome	28480-28510	6	0.806
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	MN908689	Arthrobacter phage DrSierra, complete genome	25172-25202	6	0.806
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NC_019408	Caulobacter phage CcrRogue, complete genome	123091-123121	6	0.806
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5309792-5309823	6	0.812
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	124637-124668	6	0.812
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	613759-613785	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	395235-395261	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	37894-37920	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	632718-632744	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	39129-39155	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	39129-39155	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	39129-39155	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	39129-39155	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	39129-39155	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1326658-1326684	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_LR134444	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 2, complete sequence	7484-7510	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	393359-393385	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1245057-1245083	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	JX182371	Streptomyces phage SV1, complete genome	8483-8509	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	568016-568042	6	0.778
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	315766-315792	6	0.778
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	605269-605298	6	0.8
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	335011-335040	6	0.8
NZ_CP024985_25	25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624636-8624670	35	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	236716-236750	6	0.829
NZ_CP024985_2	2.14|59290|48|NZ_CP024985|CRT	59290-59337	48	NC_004931	Streptomyces sp. EN27 plasmid pEN2701, complete sequence	9774-9821	7	0.854
NZ_CP024985_6	6.8|66528|37|NZ_CP024985|CRISPRCasFinder,CRT	66528-66564	37	MT711975	Streptomyces phage Alderaan, complete genome	16007-16043	7	0.811
NZ_CP024985_6	6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT	67042-67076	35	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	397398-397432	7	0.8
NZ_CP024985_6	6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT	67042-67076	35	MT498055	Arthrobacter phage Bumble, complete genome	33663-33697	7	0.8
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	549584-549614	7	0.774
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	63466-63496	7	0.774
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP041653	Streptomyces sp. RLB1-9 plasmid pRLB1-9.1, complete sequence	57749-57779	7	0.774
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NC_006462	Thermus thermophilus HB8 plasmid pTT27, complete sequence	183820-183850	7	0.774
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NC_005838	Thermus thermophilus HB27 plasmid pTT27, complete sequence	130148-130178	7	0.774
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	859569-859600	7	0.781
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	804640-804671	7	0.781
NZ_CP024985_14	14.1|3493220|31|NZ_CP024985|CRISPRCasFinder	3493220-3493250	31	NC_006462	Thermus thermophilus HB8 plasmid pTT27, complete sequence	13004-13034	7	0.774
NZ_CP024985_14	14.1|3493220|31|NZ_CP024985|CRISPRCasFinder	3493220-3493250	31	NZ_AP019802	Thermus thermophilus strain HC11 plasmid pHC11, complete sequence	15179-15209	7	0.774
NZ_CP024985_14	14.1|3493220|31|NZ_CP024985|CRISPRCasFinder	3493220-3493250	31	NC_017588	Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence	130885-130915	7	0.774
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	360148-360174	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	602562-602588	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1751881-1751907	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_17	17.1|4076655|27|NZ_CP024985|CRISPRCasFinder	4076655-4076681	27	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	38113-38139	7	0.741
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1585917-1585946	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	445644-445673	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	289953-289982	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	315137-315166	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	289962-289991	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1705142-1705171	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1705088-1705117	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	312799-312828	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP030273	Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence	35455-35484	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	CP047033	Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence	29135-29164	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_009040	Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence	112386-112415	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP047039	Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence	29116-29145	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP015213	Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence	72925-72954	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP051470	Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence	51244-51273	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_011960	Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence	720-749	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP015290	Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence	35615-35644	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	CP036421	Rhodobacter sphaeroides strain HJ plasmid unnamed1, complete sequence	60174-60203	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP016082	Streptomyces sp. SAT1 plasmid unnamed2, complete sequence	296333-296362	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1705449-1705478	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1705584-1705613	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	290016-290045	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP021084	Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence	214544-214573	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	222687-222716	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP015530	Rhodococcus sp. WB1 plasmid pWB1, complete sequence	25434-25463	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	482835-482864	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP033971	Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence	52010-52039	7	0.767
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP040764	Paracoccus sp. 2251 plasmid unnamed3, complete sequence	170043-170072	7	0.767
NZ_CP024985_25	25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624636-8624670	35	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	397398-397432	7	0.8
NZ_CP024985_25	25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624636-8624670	35	MT498055	Arthrobacter phage Bumble, complete genome	33663-33697	7	0.8
NZ_CP024985_25	25.15|8625148|37|NZ_CP024985|CRISPRCasFinder,CRT	8625148-8625184	37	MT711975	Streptomyces phage Alderaan, complete genome	16007-16043	7	0.811
NZ_CP024985_5	5.3|65286|33|NZ_CP024985|CRISPRCasFinder	65286-65318	33	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	926302-926334	8	0.758
NZ_CP024985_6	6.8|66528|37|NZ_CP024985|CRISPRCasFinder,CRT	66528-66564	37	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	409030-409066	8	0.784
NZ_CP024985_6	6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT	67042-67076	35	NZ_CP025615	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed3, complete sequence	139643-139677	8	0.771
NZ_CP024985_6	6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT	67042-67076	35	NZ_CP025614	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed2, complete sequence	148953-148987	8	0.771
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	253066-253096	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	169796-169826	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	244096-244126	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	225178-225208	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	245269-245299	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	220524-220554	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	227825-227855	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	225372-225402	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	225742-225772	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	239640-239670	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	225742-225772	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	228796-228826	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	225737-225767	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	245269-245299	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	239640-239670	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	225372-225402	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	231348-231378	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	267613-267643	8	0.742
NZ_CP024985_7	7.2|990864|31|NZ_CP024985|CRISPRCasFinder	990864-990894	31	NZ_CP035001	Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence	202883-202913	8	0.742
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	MF919537	Gordonia phage Toniann, complete genome	43290-43321	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	MK376959	Gordonia phage Aphelion, complete genome	43342-43373	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	KX557276	Gordonia phage Cucurbita, complete genome	44634-44665	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	448738-448769	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	7282-7313	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	565188-565219	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	228164-228195	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	68233-68264	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	18359-18390	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	81201-81232	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	574603-574634	8	0.75
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP016453	Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence	27457-27488	8	0.75
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	235789-235823	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1577469-1577503	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KX576645	Mycobacterium phage Derpp, complete genome	39140-39174	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MH513973	Mycobacterium phage Kwksand96, complete genome	39145-39179	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KY965066	Mycobacterium phage BlackStallion, complete genome	39580-39614	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MH051251	Mycobacterium phage DuchessDung, complete genome	38428-38462	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KX576646	Mycobacterium phage TyrionL, complete genome	39140-39174	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MG944223	Mycobacterium phage Trypo, complete genome	39577-39611	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	JX649096	Mycobacterium phage Serpentine, complete genome	39581-39615	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	JX649099	Mycobacterium phage Gyarad, complete genome	39579-39613	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MT897903	Mycobacterium phage DirtJuice, complete genome	39564-39598	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MH051264	Mycobacterium phage Cobra, complete genome	39582-39616	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KJ194579	Mycobacterium phage Swish, complete genome	39567-39601	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KY385382	Mycobacterium phage ImtiyazSitla, complete genome	39128-39162	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MK279891	Mycobacterium phage Wallhey, complete genome	39144-39178	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	JX649100	Mycobacterium phage Alex, complete genome	39607-39641	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	JF937109	Mycobacterium phage Yoshand, complete genome	39580-39614	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KM363597	Mycobacteriophage Zonia, complete genome	39594-39628	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KR816508	Mycobacterium phage Phamished, complete genome	39581-39615	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KR029086	Mycobacterium phage PDRPv, complete genome	39156-39190	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KY385380	Mycobacterium phage Ashraf, complete genome	39128-39162	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	NC_028803	Mycobacterium phage OSmaximus, complete genome	39617-39651	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MK279904	Mycobacterium phage RedMaple, complete genome	39583-39617	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KR029087	Mycobacterium phage PDRPxv, complete genome	39217-39251	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KX702319	Mycobacterium phage Pinkman, complete genome	39138-39172	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KP027209	Mycobacterium phage Sigman, complete genome	39566-39600	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KP027197	Mycobacterium phage FluffyNinja, complete genome	39580-39614	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MH651177	Mycobacterium phage KlimbOn, complete genome	39572-39606	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	JN698989	Mycobacterium phage JacAttac, complete genome	39566-39600	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MH479918	Mycobacterium phage Labeouficaum, complete genome	39140-39174	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MK279850	Mycobacterium phage Durga, complete genome	39594-39628	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MH479916	Mycobacterium phage GeneCoco, complete genome	39588-39622	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	KY385383	Mycobacterium phage Maskar, complete genome	39128-39162	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MK310139	Mycobacterium phage Emiris, complete genome	39562-39596	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MK279858	Mycobacterium phage JakeO, complete genome	39299-39333	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	JX649097	Mycobacterium phage Piglet, complete genome	39689-39723	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	NC_021310	Mycobacterium phage Newman, complete genome	39575-39609	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	JF704099	Mycobacterium phage KLucky39, complete sequence	39578-39612	8	0.771
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	NC_042099	Microbacterium phage Dismas, complete genome	14448-14482	8	0.771
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP022265	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plC, complete sequence	2035-2064	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP018857	Xanthomonas citri pv. citri strain LH276 plasmid pLH276.3, complete sequence	12044-12073	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP018476	Xanthomonas perforans strain LH3 plasmid pLH3.2, complete sequence	28606-28635	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP018853	Xanthomonas citri pv. citri strain LJ207-7 plasmid pLJ207-7.3, complete sequence	7176-7205	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1894714-1894743	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP024080	Xanthomonas citri pv. citri strain Xcc29-1 plasmid pXAC47, complete sequence	21088-21117	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_020798	Xanthomonas axonopodis Xac29-1 plasmid pXAC47, complete sequence	21090-21119	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP021084	Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence	200749-200778	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	284379-284408	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1528689-1528718	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	23155-23184	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	1028440-1028469	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	413378-413407	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP040822	Paraoceanicella profunda strain D4M1 plasmid pD4M1D, complete sequence	53215-53244	8	0.733
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	684686-684715	8	0.733
NZ_CP024985_25	25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624636-8624670	35	NZ_CP025615	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed3, complete sequence	139643-139677	8	0.771
NZ_CP024985_25	25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624636-8624670	35	NZ_CP025614	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed2, complete sequence	148953-148987	8	0.771
NZ_CP024985_25	25.15|8625148|37|NZ_CP024985|CRISPRCasFinder,CRT	8625148-8625184	37	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	409030-409066	8	0.784
NZ_CP024985_26	26.8|8626394|33|NZ_CP024985|CRISPRCasFinder	8626394-8626426	33	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	926302-926334	8	0.758
NZ_CP024985_2	2.1|59008|34|NZ_CP024985|CRISPRCasFinder	59008-59041	34	NZ_CP018225	Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL4, complete sequence	55952-55985	9	0.735
NZ_CP024985_2	2.1|59008|34|NZ_CP024985|CRISPRCasFinder	59008-59041	34	NZ_CP023450	Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p1, complete sequence	10568-10601	9	0.735
NZ_CP024985_2	2.3|59153|36|NZ_CP024985|CRISPRCasFinder,PILER-CR	59153-59188	36	MK511012	Pseudomonas phage BR153, partial genome	9437-9472	9	0.75
NZ_CP024985_5	5.5|65431|36|NZ_CP024985|CRISPRCasFinder	65431-65466	36	NZ_CP034812	Paracoccus sp. Arc7-R13 plasmid unnamed3, complete sequence	103468-103503	9	0.75
NZ_CP024985_6	6.1|66016|35|NZ_CP024985|CRISPRCasFinder	66016-66050	35	MT108731	Pseudomonas phage Epa43, complete genome	3837-3871	9	0.743
NZ_CP024985_6	6.14|66968|37|NZ_CP024985|CRISPRCasFinder,CRT	66968-67004	37	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	556330-556366	9	0.757
NZ_CP024985_6	6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT	67042-67076	35	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	151600-151634	9	0.743
NZ_CP024985_6	6.27|66528|38|NZ_CP024985|CRT	66528-66565	38	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	409029-409066	9	0.763
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	57354-57385	9	0.719
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP035002	Rhizobium acidisoli strain FH23 plasmid pRapFH23d, complete sequence	307730-307761	9	0.719
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NC_015314	Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence	160322-160353	9	0.719
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP024895	Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence	23815-23846	9	0.719
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	331010-331041	9	0.719
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP021119	Streptomyces sp. CLI2509 strain CLI2905 plasmid unnamed1, complete sequence	78886-78917	9	0.719
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	MH576954	Mycobacterium phage HSavage, complete genome	39583-39617	9	0.743
NZ_CP024985_23	23.2|5646347|30|NZ_CP024985|CRT	5646347-5646376	30	NC_008010	Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence	544960-544989	9	0.7
NZ_CP024985_25	25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624636-8624670	35	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	151600-151634	9	0.743
NZ_CP024985_25	25.9|8624708|37|NZ_CP024985|CRISPRCasFinder,CRT	8624708-8624744	37	NZ_CP020331	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence	556330-556366	9	0.757
NZ_CP024985_25	25.22|8625662|35|NZ_CP024985|CRISPRCasFinder	8625662-8625696	35	MT108731	Pseudomonas phage Epa43, complete genome	3837-3871	9	0.743
NZ_CP024985_26	26.6|8626246|36|NZ_CP024985|CRISPRCasFinder	8626246-8626281	36	NZ_CP034812	Paracoccus sp. Arc7-R13 plasmid unnamed3, complete sequence	103468-103503	9	0.75
NZ_CP024985_30	30.7|8632524|36|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR	8632524-8632559	36	MK511012	Pseudomonas phage BR153, partial genome	9437-9472	9	0.75
NZ_CP024985_30	30.9|8632671|34|NZ_CP024985|CRISPRCasFinder,CRT	8632671-8632704	34	NZ_CP018225	Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL4, complete sequence	55952-55985	9	0.735
NZ_CP024985_30	30.9|8632671|34|NZ_CP024985|CRISPRCasFinder,CRT	8632671-8632704	34	NZ_CP023450	Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p1, complete sequence	10568-10601	9	0.735
NZ_CP024985_4	4.24|61986|35|NZ_CP024985|PILER-CR	61986-62020	35	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1200083-1200117	10	0.714
NZ_CP024985_6	6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT	67042-67076	35	NZ_CP029836	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed6, complete sequence	71011-71045	10	0.714
NZ_CP024985_6	6.16|67114|35|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR	67114-67148	35	NC_017805	Deinococcus gobiensis I-0 plasmid P1, complete sequence	97409-97443	10	0.714
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	118289-118320	10	0.688
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	229532-229563	10	0.688
NZ_CP024985_13	13.1|3258555|35|NZ_CP024985|CRISPRCasFinder	3258555-3258589	35	NZ_AP020327	Mycobacterium avium subsp. hominissuis strain JP-H-1 plasmid p1-JPH1	81081-81115	10	0.714
NZ_CP024985_25	25.7|8624564|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624564-8624598	35	NC_017805	Deinococcus gobiensis I-0 plasmid P1, complete sequence	97409-97443	10	0.714
NZ_CP024985_25	25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT	8624636-8624670	35	NZ_CP029836	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed6, complete sequence	71011-71045	10	0.714
NZ_CP024985_27	27.23|8629693|35|NZ_CP024985|PILER-CR	8629693-8629727	35	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1200083-1200117	10	0.714
NZ_CP024985_11	11.1|2934426|32|NZ_CP024985|CRISPRCasFinder	2934426-2934457	32	CP054924	Verrucosispora sp. NA02020 plasmid unnamed, complete sequence	32460-32491	11	0.656
NZ_CP024985_20	20.1|5130922|28|NZ_CP024985|CRISPRCasFinder	5130922-5130949	28	NZ_KY887592	Citrobacter freundii strain Cf52 plasmid pCf52, complete sequence	35105-35132	13	0.536

1. spacer 2.5|59301|37|NZ_CP024985|CRISPRCasFinder,PILER-CR matches to NC_004931 (Streptomyces sp. EN27 plasmid pEN2701, complete sequence) position: , mismatch: 2, identity: 0.946

tcggcaagggagtcgacgtcaccgccgccaccaggga	CRISPR spacer
tcggcaagggcgtcgatgtcaccgccgccaccaggga	Protospacer
********** *****.********************

2. spacer 30.5|8632375|37|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR matches to NC_004931 (Streptomyces sp. EN27 plasmid pEN2701, complete sequence) position: , mismatch: 2, identity: 0.946

tccctggtggcggcggtgacgtcgactcccttgccga	CRISPR spacer
tccctggtggcggcggtgacatcgacgcccttgccga	Protospacer
********************.***** **********

3. spacer 4.19|61480|34|NZ_CP024985|PILER-CR matches to MT639641 (Microbacterium phage Phinky, complete genome) position: , mismatch: 4, identity: 0.882

-acgcacgcactcgtcggccgcgcgtgggtggagg	CRISPR spacer
aacgcccgca-tcgtcggccgcgcgtgggcggggg	Protospacer
 **** **** ******************.**.**

4. spacer 6.21|67478|36|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 4, identity: 0.889

cacgtacggcacgcaccaggccacggcgccgatggc	CRISPR spacer
cacgtacggcacgcaccaggccacggctccgacgag	Protospacer
*************************** ****.*. 

5. spacer 16.1|4022375|25|NZ_CP024985|CRISPRCasFinder matches to NC_015951 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence) position: , mismatch: 4, identity: 0.84

tccggggcggcgccccaggatcctt	CRISPR spacer
accggggcggcgccccaggctccga	Protospacer
 ****************** ***  

6. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgcgtccgcgtcgggggcgggcggcgc	Protospacer
***  ********************  

7. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgcgtccgcgtcgggggcgggcggcgc	Protospacer
***  ********************  

8. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to MT657335 (Gordonia phage Mariokart, complete genome) position: , mismatch: 4, identity: 0.852

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgccgccgcgtcggggtccggcggtag	Protospacer
**************** * *****. *

9. spacer 25.2|8624199|36|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 4, identity: 0.889

gccatcggcgccgtggcctggtgcgtgccgtacgtg	CRISPR spacer
ctcgtcggagccgtggcctggtgcgtgccgtacgtg	Protospacer
 .*.**** ***************************

10. spacer 4.19|61480|34|NZ_CP024985|PILER-CR matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.853

-acgcacgcactcgtcggccgcgcgtgggtggagg	CRISPR spacer
cgcgaacgca-tcgtcgcccgcgcgcgggtggagg	Protospacer
 .** ***** ****** *******.*********

11. spacer 5.3|65286|33|NZ_CP024985|CRISPRCasFinder matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 5, identity: 0.848

catcgtcgtacaggtccaccgcgcgcgctcgac	CRISPR spacer
cgtcgtcgtacaggtccaccgcgcgggcccggt	Protospacer
*.*********************** **.**..

12. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP035511 (Haematobacter massiliensis strain OT1 plasmid pOT1-1, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgccgccgcgccggaggcgggcggggt	Protospacer
**********.***.*********   

13. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcgggggcgagcagctt	Protospacer
  *****************.**.*** 

14. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP020613 (Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccccgtcgggggcggggggcag	Protospacer
  ***** ************* *** *

15. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
ctcgcccgcgtcgggggcgggccgctc	Protospacer
* *  ***************** *** 

16. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP029211 (Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgccgccgcgtcggtggcgagcgccac	Protospacer
************** ****.*** *  

17. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
ctcgcccgcgtcgggggcgggccgctc	Protospacer
* *  ***************** *** 

18. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to MT711975 (Streptomyces phage Alderaan, complete genome) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cacggccgcgtccggggcgggcggcat	Protospacer
*.* ******** ************  

19. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to MH825706 (Streptomyces phage Microdon, complete genome) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgccgccgcgtcgtaggcgggcgccca	Protospacer
************* .******** *..

20. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
aactgccgcgtcgggggcgggcgccgg	Protospacer
 .*.******************* * *

21. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgccgccgcatcgggggcggggatctc	Protospacer
*********.*********** . ** 

22. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
ctcgcccgcgtcgggggcgggccgctc	Protospacer
* *  ***************** *** 

23. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to MT521991 (Streptomyces phage Eklok, complete genome) position: , mismatch: 5, identity: 0.815

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
ggccgccgcgccgggggcgggccccgg	Protospacer
 *********.***********  * *

24. spacer 20.1|5130922|28|NZ_CP024985|CRISPRCasFinder matches to NZ_CP034431 (Bradyrhizobium sp. LCT2 plasmid pLCT2, complete sequence) position: , mismatch: 5, identity: 0.821

gcggagccccagggggctgcagc--ccggc	CRISPR spacer
gcggagcaccagtgggctgcagcaactg--	Protospacer
******* **** **********  *.*  

25. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

26. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggcggccgcggcgtggc	Protospacer
*************** * ********.*  

27. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

28. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

29. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

30. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

31. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

32. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

33. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

34. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtggcggtggccgcggcgtggc	Protospacer
*************** * ********.*  

35. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 5, identity: 0.833

cctgcgg-ggtggcggggcccgcggcgcgca	CRISPR spacer
-tggcggccgtggcggggcccgcggcgggca	Protospacer
 . ****  ****************** ***

36. spacer 26.8|8626394|33|NZ_CP024985|CRISPRCasFinder matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 5, identity: 0.848

gtcgagcgcgcgcggtggacctgtacgacgatg	CRISPR spacer
accgggcccgcgcggtggacctgtacgacgacg	Protospacer
..**.** ***********************.*

37. spacer 4.19|61480|34|NZ_CP024985|PILER-CR matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 6, identity: 0.824

-acgcacgcactcgtcggccgcgcgtgggtggagg	CRISPR spacer
cgcgaccgca-tcgtcgcccgcgcgcgggtggagg	Protospacer
 .**  **** ****** *******.*********

38. spacer 6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 6, identity: 0.829

agcacttcgtcggtgatccgggccagggccgcggc	CRISPR spacer
agggtttcggcggtcatccgggccagggccgcgcc	Protospacer
** ..**** **** ****************** *

39. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to MT889376 (Arthrobacter phage Phives, complete genome) position: , mismatch: 6, identity: 0.806

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
gccgccgcccgcttcggcgtctccctcgacg	Protospacer
 .**** .******************** * 

40. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to MN908689 (Arthrobacter phage DrSierra, complete genome) position: , mismatch: 6, identity: 0.806

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
gccgccgaccgcttcggcgtctccctcgacg	Protospacer
 .****  ******************** * 

41. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NC_019408 (Caulobacter phage CcrRogue, complete genome) position: , mismatch: 6, identity: 0.806

ctcgccctccgcttcggcgtctcc--ctcgcct	CRISPR spacer
atcgcccgccgcgtcggcgtctccaagtcgc--	Protospacer
 ****** **** ***********   ****  

42. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.812

ccggcgtcggcgggccgcacccgc---cgggcacg	CRISPR spacer
tcggcgtcgccgggccgcaccagcgcgcgggc---	Protospacer
.******** *********** **   *****   

43. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 6, identity: 0.812

-ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
gccagcg-aggcgagccgcaccagccgggcacc	Protospacer
 **.***  ****.******** ********* 

44. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

45. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

46. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

47. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

48. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

49. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

50. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

51. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

52. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcccgccgcgtcggcggcgggcggtcc	Protospacer
  ************ *********.. 

53. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
tgcgctcgcgtcgggggcgggcggcgc	Protospacer
.**  .*******************  

54. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_LR134444 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
caccgccgcgtcggggccgggcgcgaa	Protospacer
*.************** ******   .

55. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
cgccgccgcgtcggtgtcgggcgagga	Protospacer
************** * ******.  .

56. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcgcgacgcgtcggggccgggcggctc	Protospacer
   ** ********** ********* 

57. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to JX182371 (Streptomyces phage SV1, complete genome) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gaccgcctcgtcgggcgcgggcggcat	Protospacer
 .***** ******* *********  

58. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gcgcgacgcgtcggggccgggcggctc	Protospacer
   ** ********** ********* 

59. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 6, identity: 0.778

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
ggccgccacctcgggggcgggcggggt	Protospacer
 ******.* **************   

60. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tctgcggggcggcggggcccgcgggcgtca	Protospacer
.********.**************    **

61. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cgtggacggtgccggcgcccgcggcgcgca	Protospacer
* ** . **** *** **************

62. spacer 25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 6, identity: 0.829

gccgcggccctggcccggatcaccgacgaagtgct	CRISPR spacer
ggcgcggccctggcccggatgaccgccgaaaccct	Protospacer
* ****************** **** ****.. **

63. spacer 2.14|59290|48|NZ_CP024985|CRT matches to NC_004931 (Streptomyces sp. EN27 plasmid pEN2701, complete sequence) position: , mismatch: 7, identity: 0.854

--gcgaccgccactcggcaagggagtcgacgtcaccgccgccaccaggga	CRISPR spacer
cggcaagcgc--atcggcaagggcgtcgatgtcaccgccgccaccaggga	Protospacer
  **.* ***   ********** *****.********************

64. spacer 6.8|66528|37|NZ_CP024985|CRISPRCasFinder,CRT matches to MT711975 (Streptomyces phage Alderaan, complete genome) position: , mismatch: 7, identity: 0.811

gcccgcgccgccgagctgtacgacgagcaggaagcgg	CRISPR spacer
gagcgcgccgccgagctgtacgcggagcaggcgacgg	Protospacer
*  *******************  ******* ..***

65. spacer 6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 7, identity: 0.8

agcacttcgtcggtgatccgggccagggccgcggc	CRISPR spacer
agggtctcggcggtcatccgggccagggccgcgcc	Protospacer
** ...*** **** ****************** *

66. spacer 6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT matches to MT498055 (Arthrobacter phage Bumble, complete genome) position: , mismatch: 7, identity: 0.8

agcacttcgtcggtgatccgggccagggccgcggc	CRISPR spacer
atcccggcctcggcgatccgggcccgggccgcggc	Protospacer
* * *  * ****.********** **********

67. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 7, identity: 0.774

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
cgggtgctcctctccggcgtctccctcgccg	Protospacer
*  *. **** **.**************** 

68. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 7, identity: 0.774

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
atcgccgtccgcttcggcgtcttccagccgt	Protospacer
 ***** ***************.**   * *

69. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP041653 (Streptomyces sp. RLB1-9 plasmid pRLB1-9.1, complete sequence) position: , mismatch: 7, identity: 0.774

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
gtcaactgccgcttcggcgtcgccctcgccc	Protospacer
 **. *. ************* ********.

70. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NC_006462 (Thermus thermophilus HB8 plasmid pTT27, complete sequence) position: , mismatch: 7, identity: 0.774

ctcgccc---tccgcttcggcgtctccctcgcct	CRISPR spacer
---ggccgggcccgcttcggcctctcccacgcct	Protospacer
   * **   .********** ****** *****

71. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NC_005838 (Thermus thermophilus HB27 plasmid pTT27, complete sequence) position: , mismatch: 7, identity: 0.774

ctcgccc---tccgcttcggcgtctccctcgcct	CRISPR spacer
---ggccgggcccgcttcggcctctcccacgcct	Protospacer
   * **   .********** ****** *****

72. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

ccggcgtcggcgggccgcacccgccgggcacg---	CRISPR spacer
acggcgtcggcgggtcgctcccgc---gctcgccg	Protospacer
 *************.*** *****   ** **   

73. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
gcgaagtcggcgggccgcatcagccgggagcg	Protospacer
 **. **************.* ****** .**

74. spacer 14.1|3493220|31|NZ_CP024985|CRISPRCasFinder matches to NC_006462 (Thermus thermophilus HB8 plasmid pTT27, complete sequence) position: , mismatch: 7, identity: 0.774

cgagccccgctcccctcagcccctcagcccc	CRISPR spacer
ccagccccgctccccccagcgcctcggggac	Protospacer
* *************.**** ****.*   *

75. spacer 14.1|3493220|31|NZ_CP024985|CRISPRCasFinder matches to NZ_AP019802 (Thermus thermophilus strain HC11 plasmid pHC11, complete sequence) position: , mismatch: 7, identity: 0.774

cgagccccgctcccctcagcccctcagcccc	CRISPR spacer
ccagccccgctccccccagcgcctcggggac	Protospacer
* *************.**** ****.*   *

76. spacer 14.1|3493220|31|NZ_CP024985|CRISPRCasFinder matches to NC_017588 (Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence) position: , mismatch: 7, identity: 0.774

cgagccccgctcccctcagcccctcagcccc	CRISPR spacer
ccagccccgctccccccagcgcctcggggac	Protospacer
* *************.**** ****.*   *

77. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

78. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gaccgccgcgtcgggggccggcgaggc	Protospacer
 .**************** ****.   

79. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

80. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

81. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

82. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

83. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

84. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

85. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

86. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

87. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

88. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

89. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

90. spacer 17.1|4076655|27|NZ_CP024985|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.741

cgccgccgcgtcgggggcgggcggctg	CRISPR spacer
gctcgccgcgtcggcggcgggcggtcc	Protospacer
  .*********** *********.. 

91. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

92. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

93. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

94. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

95. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

96. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

97. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

98. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

99. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP030273 (Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

100. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to CP047033 (Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

101. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_009040 (Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

102. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP047039 (Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

103. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP015213 (Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

104. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP051470 (Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

105. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_011960 (Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

106. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP015290 (Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

107. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to CP036421 (Rhodobacter sphaeroides strain HJ plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tcacgaaggtggcgaggcccgcggcgcgca	Protospacer
.*   ..*******.***************

108. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP016082 (Streptomyces sp. SAT1 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
ggtacggggcggcggcgcccgcggcgcggc	Protospacer
  *.*****.***** ************  

109. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

110. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

111. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

112. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP021084 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
agtgcagggtggcggggcccgcggtggtga	Protospacer
  ***.******************.*   *

113. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tgcgcggggtggcgggggccgcgccgggta	Protospacer
. .************** ***** ** *.*

114. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP015530 (Rhodococcus sp. WB1 plasmid pWB1, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtgacagggcccgcgcgggcct	Protospacer
***********.*.*********  *  * 

115. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca-	CRISPR spacer
tgggcggggcggcggggccggcggcg-gcgt	Protospacer
.  ******.********* ****** **. 

116. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP033971 (Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcgtgatggcggggcccgcgtcatcga	Protospacer
****** *.************** *..  *

117. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP040764 (Paracoccus sp. 2251 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cctgcggggtgccggggcccgggcgctgcc	Protospacer
*********** ********* *   .** 

118. spacer 25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 7, identity: 0.8

gccgcggccctggcccggatcaccgacgaagtgct	CRISPR spacer
ggcgcggccctggcccggatgaccgccgagaccct	Protospacer
* ****************** **** ***... **

119. spacer 25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to MT498055 (Arthrobacter phage Bumble, complete genome) position: , mismatch: 7, identity: 0.8

gccgcggccctggcccggatcaccgacgaagtgct	CRISPR spacer
gccgcggcccgggcccggatcgccgaggccgggat	Protospacer
********** **********.**** *  * * *

120. spacer 25.15|8625148|37|NZ_CP024985|CRISPRCasFinder,CRT matches to MT711975 (Streptomyces phage Alderaan, complete genome) position: , mismatch: 7, identity: 0.811

ccgcttcctgctcgtcgtacagctcggcggcgcgggc	CRISPR spacer
ccgtcgcctgctccgcgtacagctcggcggcgcgctc	Protospacer
***.. *******  *******************  *

121. spacer 5.3|65286|33|NZ_CP024985|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 8, identity: 0.758

catcgtcgtacaggtccaccgcgcgcgctcgac	CRISPR spacer
cggggtcatacaggtacaccgcgcgcgcgggat	Protospacer
*.  ***.******* ************  **.

122. spacer 6.8|66528|37|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.784

gcccgcgccgccgagctgtacgacgagcaggaagcgg	CRISPR spacer
ccgcgcgccgccgaccagtacgacgagcagctggccg	Protospacer
 * *********** * *************  .** *

123. spacer 6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP025615 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.771

agcacttcgtcggtgatccgggccagggccgcggc	CRISPR spacer
cgatgcgcgtcgatgatccgggccagggccgccgc	Protospacer
 *   . *****.******************* **

124. spacer 6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP025614 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.771

agcacttcgtcggtgatccgggccagggccgcggc	CRISPR spacer
cgatgcgcgtcgatgatccgggccagggccgccgc	Protospacer
 *   . *****.******************* **

125. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
ctcgccagccgcttcggcgtctccgaacgca	Protospacer
******  ****************     * 

126. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
ctcgcccgccgcatcggcgtctccgtgcaga	Protospacer
******* **** *********** *     

127. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

128. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

129. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

130. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

131. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

132. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

133. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

134. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

135. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

136. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

137. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

138. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

139. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

140. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

141. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

142. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
ctcgcccgccgcatcggcgtctccgtgcaga	Protospacer
******* **** *********** *     

143. spacer 7.2|990864|31|NZ_CP024985|CRISPRCasFinder matches to NZ_CP035001 (Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence) position: , mismatch: 8, identity: 0.742

ctcgccctccgcttcggcgtctccctcgcct	CRISPR spacer
aaggaagtccgcttcggcgtcgccctctcct	Protospacer
   *   ************** ***** ***

144. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to MF919537 (Gordonia phage Toniann, complete genome) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
ctggcgtcagcgggccgaacccgccggctgga	Protospacer
*.******.******** ********* .. .

145. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to MK376959 (Gordonia phage Aphelion, complete genome) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
ctggcgtcagcgggccgaacccgccggctgga	Protospacer
*.******.******** ********* .. .

146. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to KX557276 (Gordonia phage Cucurbita, complete genome) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
ctggcgtcagcgggccgaacccgccggctgga	Protospacer
*.******.******** ********* .. .

147. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

148. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

149. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

150. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

151. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

152. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

153. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

154. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cagaggtcgccgggccgcgcccgccgggcgaa	Protospacer
* *. **** ********.**********. .

155. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP016453 (Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence) position: , mismatch: 8, identity: 0.75

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
ccggcgtcggcaggccggacccggccgatgag	Protospacer
***********.***** ***** * *... *

156. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
tcaccgaggccgccgccgaggaccccgggccggtg	Protospacer
********************* .**** *  * . 

157. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
tcaccgaggccgccgccgaggaccccgggccggtg	Protospacer
********************* .**** *  * . 

158. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KX576645 (Mycobacterium phage Derpp, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

159. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MH513973 (Mycobacterium phage Kwksand96, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

160. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KY965066 (Mycobacterium phage BlackStallion, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

161. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MH051251 (Mycobacterium phage DuchessDung, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

162. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KX576646 (Mycobacterium phage TyrionL, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

163. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MG944223 (Mycobacterium phage Trypo, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

164. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to JX649096 (Mycobacterium phage Serpentine, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

165. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to JX649099 (Mycobacterium phage Gyarad, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

166. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MT897903 (Mycobacterium phage DirtJuice, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

167. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MH051264 (Mycobacterium phage Cobra, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

168. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KJ194579 (Mycobacterium phage Swish, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

169. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KY385382 (Mycobacterium phage ImtiyazSitla, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

170. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MK279891 (Mycobacterium phage Wallhey, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

171. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to JX649100 (Mycobacterium phage Alex, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

172. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to JF937109 (Mycobacterium phage Yoshand, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

173. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KM363597 (Mycobacteriophage Zonia, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

174. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KR816508 (Mycobacterium phage Phamished, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

175. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KR029086 (Mycobacterium phage PDRPv, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

176. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KY385380 (Mycobacterium phage Ashraf, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

177. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to NC_028803 (Mycobacterium phage OSmaximus, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

178. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MK279904 (Mycobacterium phage RedMaple, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

179. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KR029087 (Mycobacterium phage PDRPxv, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

180. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KX702319 (Mycobacterium phage Pinkman, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

181. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KP027209 (Mycobacterium phage Sigman, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

182. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KP027197 (Mycobacterium phage FluffyNinja, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

183. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MH651177 (Mycobacterium phage KlimbOn, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

184. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to JN698989 (Mycobacterium phage JacAttac, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

185. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MH479918 (Mycobacterium phage Labeouficaum, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

186. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MK279850 (Mycobacterium phage Durga, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

187. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MH479916 (Mycobacterium phage GeneCoco, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

188. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to KY385383 (Mycobacterium phage Maskar, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

189. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MK310139 (Mycobacterium phage Emiris, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

190. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MK279858 (Mycobacterium phage JakeO, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

191. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to JX649097 (Mycobacterium phage Piglet, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

192. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to NC_021310 (Mycobacterium phage Newman, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

193. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to JF704099 (Mycobacterium phage KLucky39, complete sequence) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ccaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
.*******.************* ****. .** .*

194. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to NC_042099 (Microbacterium phage Dismas, complete genome) position: , mismatch: 8, identity: 0.771

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
cccccgaggccgccgccgaggccgccgcgtggggc	Protospacer
.* *******************. ***** .*  *

195. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP022265 (Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plC, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
ggcctcgggtggcggcgccagcggcgcgca	Protospacer
  . . ********* *** **********

196. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP018857 (Xanthomonas citri pv. citri strain LH276 plasmid pLH276.3, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
ggcctcgggtggcggcgccagcggcgcgca	Protospacer
  . . ********* *** **********

197. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP018476 (Xanthomonas perforans strain LH3 plasmid pLH3.2, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
ggcctcgggtggcggcgccagcggcgcgca	Protospacer
  . . ********* *** **********

198. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP018853 (Xanthomonas citri pv. citri strain LJ207-7 plasmid pLJ207-7.3, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
ggcctcgggtggcggcgccagcggcgcgca	Protospacer
  . . ********* *** **********

199. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
attcgggggcggcggggcccgcggcgccgg	Protospacer
 .*  ****.*****************  .

200. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP024080 (Xanthomonas citri pv. citri strain Xcc29-1 plasmid pXAC47, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
ggcctcgggtggcggcgccagcggcgcgca	Protospacer
  . . ********* *** **********

201. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_020798 (Xanthomonas axonopodis Xac29-1 plasmid pXAC47, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
ggcctcgggtggcggcgccagcggcgcgca	Protospacer
  . . ********* *** **********

202. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP021084 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cggtgagggtggcgtggcccgcggcgtgcg	Protospacer
*    .******** ***********.**.

203. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
agcgctgggtggcggcgcccgcggcgatcg	Protospacer
  .** ********* **********  *.

204. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
agcgctgggtggcggcgcccgcggcgatcg	Protospacer
  .** ********* **********  *.

205. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
agggcgaggtggcgggggccgcggcggacg	Protospacer
   ***.********** ******** .*.

206. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
agggcgaggtggcgggggccgcggcggacg	Protospacer
   ***.********** ******** .*.

207. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
cgggcggggtggcgggtgccgcggcgtcgg	Protospacer
*  *************  ********.  .

208. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP040822 (Paraoceanicella profunda strain D4M1 plasmid pD4M1D, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tgagcggcgtggcggtgcccgcggcgtcga	Protospacer
.  **** ******* **********.  *

209. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 8, identity: 0.733

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
agggcgaggtggcgggggccgcggcggacg	Protospacer
   ***.********** ******** .*.

210. spacer 25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025615 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.771

gccgcggccctggcccggatcaccgacgaagtgct	CRISPR spacer
gcggcggccctggcccggatcatcgacgcgcatcg	Protospacer
** *******************.***** .   * 

211. spacer 25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025614 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.771

gccgcggccctggcccggatcaccgacgaagtgct	CRISPR spacer
gcggcggccctggcccggatcatcgacgcgcatcg	Protospacer
** *******************.***** .   * 

212. spacer 25.15|8625148|37|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.784

ccgcttcctgctcgtcgtacagctcggcggcgcgggc	CRISPR spacer
cggccagctgctcgtcgtactggtcggcggcgcgcgg	Protospacer
* **.  ************* * *********** * 

213. spacer 26.8|8626394|33|NZ_CP024985|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 8, identity: 0.758

gtcgagcgcgcgcggtggacctgtacgacgatg	CRISPR spacer
atcccgcgcgcgcggtgtacctgtatgaccccg	Protospacer
.**  ************ *******.***  .*

214. spacer 2.1|59008|34|NZ_CP024985|CRISPRCasFinder matches to NZ_CP018225 (Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL4, complete sequence) position: , mismatch: 9, identity: 0.735

accgaccacccgcggattgccacagccgctcgcg	CRISPR spacer
gcccaaggagcgcggttcgccacagccgctcgcg	Protospacer
.** *  .  ***** *.****************

215. spacer 2.1|59008|34|NZ_CP024985|CRISPRCasFinder matches to NZ_CP023450 (Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

accgaccacccgcggattgccacagccgctcgcg	CRISPR spacer
gcccaaggagcgcggttcgccacagccgctcgcg	Protospacer
.** *  .  ***** *.****************

216. spacer 2.3|59153|36|NZ_CP024985|CRISPRCasFinder,PILER-CR matches to MK511012 (Pseudomonas phage BR153, partial genome) position: , mismatch: 9, identity: 0.75

ggtcgtcctggttctgctcgtcgccggtctcctctg	CRISPR spacer
actcgtcctggttctgctcgtcggtggtcagcttgt	Protospacer
. ********************* .****  **.  

217. spacer 5.5|65431|36|NZ_CP024985|CRISPRCasFinder matches to NZ_CP034812 (Paracoccus sp. Arc7-R13 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.75

ctgctcgtccaggccgagagcatcggcaatctggtt	CRISPR spacer
cgcctcgtccaagccgagagcatccgcaaaggcgct	Protospacer
*  ********.************ ****    *.*

218. spacer 6.1|66016|35|NZ_CP024985|CRISPRCasFinder matches to MT108731 (Pseudomonas phage Epa43, complete genome) position: , mismatch: 9, identity: 0.743

ccgcaccgggtcgcccgctgtacgttcggccagtc	CRISPR spacer
ttggaccgggtcgcccgctggaagttcggaggctc	Protospacer
..* **************** * ******  . **

219. spacer 6.14|66968|37|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 9, identity: 0.757

ccgcccggcgctgcccgcccctgcccacgcggaaggt	CRISPR spacer
ccgcccggcgcagcccgcccgtgcccgagggcaatcc	Protospacer
*********** ******** *****. * * **  .

220. spacer 6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 9, identity: 0.743

agcacttcgtcggtgatccgggccagggccgcggc	CRISPR spacer
tggtcgcggtcggtgatccgggccagagcggcgtc	Protospacer
 *  * . ******************.** *** *

221. spacer 6.27|66528|38|NZ_CP024985|CRT matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.763

gcccgcgccgccgagctgtacgacgagcaggaagcggg	CRISPR spacer
ccgcgcgccgccgaccagtacgacgagcagctggccga	Protospacer
 * *********** * *************  .** *.

222. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 9, identity: 0.719

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
tcggcgtcggctggccgcaccggccgaaggac	Protospacer
.********** ********* ****.. .  

223. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP035002 (Rhizobium acidisoli strain FH23 plasmid pRapFH23d, complete sequence) position: , mismatch: 9, identity: 0.719

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
tcggcgtcggctggccgcaccggccgaaggac	Protospacer
.********** ********* ****.. .  

224. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NC_015314 (Pseudonocardia dioxanivorans CB1190 plasmid pPSED01, complete sequence) position: , mismatch: 9, identity: 0.719

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
ccggtgtcggcgggccgcaaccgactacctgc	Protospacer
****.************** *** * . *   

225. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP024895 (Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
cgcactggggctggccgcacccgcagggcaca	Protospacer
*  .*   *** ************ ******.

226. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 9, identity: 0.719

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
ctggcgtcgccgggccgcccccgccaaaggag	Protospacer
*.******* ******** ******... . *

227. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP021119 (Streptomyces sp. CLI2509 strain CLI2905 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
aggtcgtcggcgggcagcgcccgccggtcttc	Protospacer
  * *********** **.******** * . 

228. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to MH576954 (Mycobacterium phage HSavage, complete genome) position: , mismatch: 9, identity: 0.743

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
ctaccgagaccgccgccgaggcacccgtcgaggtc	Protospacer
..******.************* ****. .** .*

229. spacer 23.2|5646347|30|NZ_CP024985|CRT matches to NC_008010 (Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence) position: , mismatch: 9, identity: 0.7

cctgcggggtggcggggcccgcggcgcgca	CRISPR spacer
tgggcggggtggcggggcacgcgggcctgt	Protospacer
.  *************** *****  *   

230. spacer 25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 9, identity: 0.743

gccgcggccctggcccggatcaccgacgaagtgct	CRISPR spacer
gacgccgctctggcccggatcaccgaccgcgacca	Protospacer
* *** **.****************** . *  * 

231. spacer 25.9|8624708|37|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP020331 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM593, complete sequence) position: , mismatch: 9, identity: 0.757

accttccgcgtgggcaggggcgggcagcgccgggcgg	CRISPR spacer
ggattgccctcgggcacgggcgggctgcgccgggcgg	Protospacer
.  ** * * .***** ******** ***********

232. spacer 25.22|8625662|35|NZ_CP024985|CRISPRCasFinder matches to MT108731 (Pseudomonas phage Epa43, complete genome) position: , mismatch: 9, identity: 0.743

gactggccgaacgtacagcgggcgacccggtgcgg	CRISPR spacer
gagcctccgaacttccagcgggcgacccggtccaa	Protospacer
** .  ****** * **************** *..

233. spacer 26.6|8626246|36|NZ_CP024985|CRISPRCasFinder matches to NZ_CP034812 (Paracoccus sp. Arc7-R13 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.75

aaccagattgccgatgctctcggcctggacgagcag	CRISPR spacer
agcgcctttgcggatgctctcggcttggacgaggcg	Protospacer
*.*    **** ************.********  *

234. spacer 30.7|8632524|36|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR matches to MK511012 (Pseudomonas phage BR153, partial genome) position: , mismatch: 9, identity: 0.75

cagaggagaccggcgacgagcagaaccaggacgacc	CRISPR spacer
acaagctgaccaccgacgagcagaaccaggacgagt	Protospacer
  .**  ****. ********************* .

235. spacer 30.9|8632671|34|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP018225 (Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL4, complete sequence) position: , mismatch: 9, identity: 0.735

cgcgagcggctgtggcaatccgcgggtggtcggt	CRISPR spacer
cgcgagcggctgtggcgaaccgcgctccttgggc	Protospacer
****************.* *****  .  * **.

236. spacer 30.9|8632671|34|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP023450 (Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

cgcgagcggctgtggcaatccgcgggtggtcggt	CRISPR spacer
cgcgagcggctgtggcgaaccgcgctccttgggc	Protospacer
****************.* *****  .  * **.

237. spacer 4.24|61986|35|NZ_CP024985|PILER-CR matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.714

ccggacggccccggcaaggttggcgccgttgtcag	CRISPR spacer
accgacgcccccggccaggttggcgccgccgatga	Protospacer
 * **** ******* ************..* ...

238. spacer 6.15|67042|35|NZ_CP024985|CRISPRCasFinder,CRT matches to NZ_CP029836 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed6, complete sequence) position: , mismatch: 10, identity: 0.714

agcacttcgtcggtgatccgggccagggccgcggc	CRISPR spacer
tggtgcgcgtcgatgatccgggccagggccgcttg	Protospacer
 *   . *****.*******************   

239. spacer 6.16|67114|35|NZ_CP024985|CRISPRCasFinder,CRT,PILER-CR matches to NC_017805 (Deinococcus gobiensis I-0 plasmid P1, complete sequence) position: , mismatch: 10, identity: 0.714

tcccgtccctgatggcggccgtgacctgctgggtt	CRISPR spacer
acaccgggctgatggcggtcgtgacctactggggc	Protospacer
 * *    **********.********.***** .

240. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 10, identity: 0.688

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
tcggcgtcggctggccgcaccggcccaaagac	Protospacer
.********** ********* *** .. .  

241. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
accatgtcggtgggccgcgcccgccgggtgtt	Protospacer
 * ..*****.*******.*********... 

242. spacer 13.1|3258555|35|NZ_CP024985|CRISPRCasFinder matches to NZ_AP020327 (Mycobacterium avium subsp. hominissuis strain JP-H-1 plasmid p1-JPH1) position: , mismatch: 10, identity: 0.714

tcaccgaggccgccgccgaggctcccgcgaagccc	CRISPR spacer
gcggcgcggccgccgccgaggctgccgcggcggtg	Protospacer
 *. ** **************** *****. * . 

243. spacer 25.7|8624564|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NC_017805 (Deinococcus gobiensis I-0 plasmid P1, complete sequence) position: , mismatch: 10, identity: 0.714

aacccagcaggtcacggccgccatcagggacggga	CRISPR spacer
gccccagtaggtcacgaccgccatcagcccggtgt	Protospacer
. *****.********.**********    * * 

244. spacer 25.8|8624636|35|NZ_CP024985|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029836 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed6, complete sequence) position: , mismatch: 10, identity: 0.714

gccgcggccctggcccggatcaccgacgaagtgct	CRISPR spacer
caagcggccctggcccggatcatcgacgcgcacca	Protospacer
   *******************.***** .   * 

245. spacer 27.23|8629693|35|NZ_CP024985|PILER-CR matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.714

ctgacaacggcgccaaccttgccggggccgtccgg	CRISPR spacer
tcatcggcggcgccaacctggccgggggcgtcggt	Protospacer
... *..************ ******* **** * 

246. spacer 11.1|2934426|32|NZ_CP024985|CRISPRCasFinder matches to CP054924 (Verrucosispora sp. NA02020 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.656

ccggcgtcggcgggccgcacccgccgggcacg	CRISPR spacer
attttcacggcgggacgctcccgccgggcaac	Protospacer
 .  .  ******* *** ***********  

247. spacer 20.1|5130922|28|NZ_CP024985|CRISPRCasFinder matches to NZ_KY887592 (Citrobacter freundii strain Cf52 plasmid pCf52, complete sequence) position: , mismatch: 13, identity: 0.536

gcggagccccagggggctgcagcccggc	CRISPR spacer
gccgggctgcaggccccaggggcgagcc	Protospacer
** *.**. ****   * * .**  * *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	143990 : 192902	35	Paenibacillus_phage(100.0%)	transposase	NA
DBSCAN-SWA_2	209435 : 263667	40	Cannes_8_virus(50.0%)	transposase	NA
DBSCAN-SWA_3	6389494 : 6396563	8	Streptomyces_phage(28.57%)	NA	NA
DBSCAN-SWA_4	8452510 : 8500516	37	Paenibacillus_phage(40.0%)	transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP024985|143990:192902|DBSCAN-SWA
GCTACCGCAGCAGGATCATCTTCCGGAGCAGGTGGAAGCCAGCTCGGCCGTAGAGCTGTCTCTTGATCTTCTTGATGCGGTTCACGGCTCCCTCGACGCTGCCCGAGCTCCAGTCCAGGGTGAGGCCGGCGATCACGGCGTCGAGGTCTCGCCGCAGGTGGAGCGCGAAGCCAGTGAGCCCGGGCAGCCGGCTGGCTTCGACTGCGTCGATCCAGGCAGGGAGCGTGGCGCCGAGGCGGTCGGTGAGCATCTCGCCGAAGTCGCGGACATGTCCGGCAGCCGTGTCCAGTTCCGGACAACGGGTCAAAAGGTCCTTGAGGCCGATGCGGTCCTCCTCACTCAGCGTGGCGGGGTGGCGGGTGAGCCAGCCGGTCACCTGCCGTACGGTCGCTGGCCGTGGCGGTGCGGCGGACGGGTCCCTGCGCAAGGTGGCGATGTGGGCTCGGACCATGCCGTAGGTGACGGGAGCCTGCTCGGCGACCAGTTCGCCGTGGAGTTGGGTGACGCTGGTGCATCCCTCGGTGAATCGTCGTTCGAGGTAGGGCTTGTAGGGATCGAGTCTGCTGGGCCGGGGTCGGTTCTCGCGGATGGTGTCCTGCCAGCGTGAGGCGTTCGCGTACCGGAGGACGGTGTTGAGGCCCCAGCCCAGATGCCGGGCGATCGCCCGGCGCGAGTGCCCCTGGGCGAGCATCTCGTCGACCAGGGCGTGTGCGGCCTTCTTTCGCGCGGCCCGCCGGCCGACGGGCTCCGCGTCGTCTTGCGATCCCCCTGAAGTCGGTCGGGTGGCCTCCGTCAGCGTGCCGCTGGGCGCCGGCGTGCGCAGACAGTCGCGGTGGGCAGCGACGCAGGTCTCCACGGCGCGGCCGAGGCCCTGCCACAGATGGAACCGGTCGGCGACCTGCAAAGCGTCGGGTGCACCGCGCCGCGCGCCCTCGGCGTAGGCACCCGCCCGGTCCCGGCAGATGATCTCCACGCCGGGATGGCAGTCCAGCCAAGCTGCCAGCGGCCCGGCTTCACGGGTCGGGAGCACGTCGACCACGCGATGGTCTTCGACGCTGGTCAAGACGGTGGAGTAGGTCTGGCCGCGACGGATCGCAAAGTCGTCCACGCCCAGCACGCGTGGAGTACTGAATCGCGGATCGGGCAACGCCATGACCCTGCGTAACAAGGTCATCCGTCCCGCACCGAAGCCGAGCTGGGCCGCCAGTCGAGCGCCGGCTCGTCCCGCCAAGGCGAGCCCCACCCGCTCCAGGGCGCGGTTCAGCCGCGTGGTGAACCGCGGGTACGGCGCGGCCAGCCGGGAGAACGGCTCGGCGAACGTTCGGCGCGGACAGTCCGCCGACCCGCAGATGAATCGCCGGACCATCAGCCGGATCACAAAGCCCTGCTCAGCGAGCGGAAGGTCCTTCAGCCTGCGCTGGTAACGGTCGTGGACCCGGTCCGCGAAGCGGCCGCAGTCCGGACACGCCGCCCCCGCCATGCGGCCTCTTGCTACCACCTCGACCGTGCCGAACGCGACCGTAACCGCCTCGACCCCCACATCGTCGATCCCGTCGAACACCAGCGAATCCCAGAACGGTGCATCGGTCTGCATGACCAGCACCATCACTGTTCACAGCCAGCCAGAGCAGCCAGCGGAATGCACCTGAGGGAGCGTCACTTCCGGCCTTCAGACGCCAAGGCGTGCGCCGTCTCGCACGAGTCAGTCACTCGCAATCGAACACCGAGGTCACGCTCCGCGATGGTTCCCCAAGATCGGTGTCAGAACCCGGTTCTCGTGAACAGAACCACCGGGCCATCGGGCTCAGGACCACTCCGACCGAAACCGCCTTCTCGACTACGTTCCGTGGTGCTCGTAGGCGCGCGGGAGATCGACTTTTAATGTGTCACGCTCCGCCCGCGAAACCGGGCTGAGGGCCCCTCCAGGCTCCGAGAAACGGACATACGGGGACGGATTCCAGGCAGCGTGACACTTTCCTGAGGGAGCGTGACAGCAGGTGTCACACTCACGGTCCGTCAGCGTGACACGGTCGGGCACAGCCGCGGCTGGTTGTTCAGGAGAGGCCCGCGTCAGTTGTCCCGACCCGGGCAGTTTGGTCCCCGTCTCAAGCGATCTGGTCCGATTCGCTTGGCGTCTCAGATGATCTGGTCTGGGCCAGCGGCGCCTGTCTGCCCCCGAGGCAGAGCCTGGTCCTCAGCGACGCTGCGGACTGGCATCAAGCTCTGCAACGGTGGGCTTCTGGCCCGGTTGTTCCGCCACTTCGCCAGGGCTGACCAGGACAGCTACTGGGGATCGGCCCAGGCGATACTTTCACCCATGATTGTCAGATGCTTGGAGATCATCCATCCCGACGGCGATTACCCCGTCGCAGAGTTTGATGGGATCCGGGTGGGCGGTGTCTACCCGGTTCTGGAGATGGTCACAGACGACGACCACTGCTACATCCGTGTGCTCGGCCCCGACTCACCCGACCCCGGACTGGAATGGGACCCCGTCTCCTTCGAGACAGTGGACACCCGGATACCGCCCGGCTGGACCCTCGCCATCGCCGGCGGCCGCACCCGCCTCGCGGATGCCCGCTGGCAGCGTCCCGGCTTCTGGACCGACTACTACCGCGGCGACCCGCAGGCCCGGGCCGACTACGACCACGTGAAGAGCGAACTCCTCGCAGCCGCCCCACCGCGCGAGAACTGACCCCCGCGCCCGGGTGCTCTCTCCCGTATCCAAACCATCAGGTCAGCAGCCCGACGGTCAGCGCGAAGAAGCCGGGAGAGCTCTCCAATCGCGGGGGGCCCAGGCCTGCCAGCGACGGACCAGATCAACTTAGAACCCGTTGTTGTTCCGAACTTGATGGCTGCGTTTTCGCTGGTGGGAGTGGGTGCTGTTCAGCCGAGGCAGGGATGAGGCGTCCTGTTTCTCGTTGAGCGTGCGGGGTGGCTGATGGTGTCGGTGCTGGGTCTTCTGGAGGCGAAGGAGTCGGCTGCGCGGGAGGTCATCGAGCGGCTGCGTGATGAGGCCGATCGGATCCTGGCTGAGCTCGTGGAGGCGGAAGGCAGTCTGGAGCGGCTGGTCATCGCGCGGGAGACGGTGGCAGAGGTTCTCAACGGCCCGGCCGTTGCGGCCAAGGAGGCTGCGGTGAAGGACGTGGATGAGGCCCCGGCTGGGGTGATGGTGGTGCCGCGTCGTCGTGAGGGCCTCTCGGTTCGTGTGCTGCCGGAGGAGTATCAGCGGGTCATGGCCGTGGTGGGGGCCAGGGACGGAGTGCGGGCCAGGGACCTGACCGTCGCCCTGGGGCGGGAGGCGGTGCCCGCGAAGATCGAGTGTGTGCGGTCGATGGCCAAGCGGCTGGTCGCGCGTGGGTGGGCGGTGGAGGAGACACCCGGCGTGTTCACCCCCGCAGCCGGGTCACGTGGGCCTGCCGCTGCCGGGTGACCCGGTCGCCGTGCGAGGCGGCGTCCCATGACCATGGTCATGGACCACATCACCATCGCCTCGTGGGTGGCGGGCAGGCGTTCGTAGTCCCGGACCAAGCGGCGGCGGTGCATCAGCCAGGCCAGTGTCCGCTCGACGACCCAACGGCGGGGCAGGACCACGAATCCCTTCTGGTCATCGCTTCGTTTGACGATCGTGAGCGCCAGGCCGAGAACGTCCCTGGCCCAGTCGACGAGCCAGCCTGCATAGCCTCCGTCGGCCCACGCGAGTGTGATCTTGCGGCGGAGTTCGCGGAGCCGGTTCAAGACCGGCACGGCCGCATCACGGTCCTGGACGGACGCCGGGGTGACGTGGACGACCAGGAGAAGGCCTGCAGTGTCCACCGCCAGGTGGCGCTTGCGGCCGCCGGCTTTCTTGCCTTTGTCCCAGCCGCGTGATCCGGCGGCGCCGGTGTCGGCCGCCCGCAGGGACTGCGAGTCCACGATCGCGGCCGTCGGCTCCGCTCTTCGTCCCTCCGTTTCCCGCACCCGGGCTCGGAGCCGGTGGTGGAACTCGGCGATCAGGCCCTGGAGGCGCCAGCGGCGGAAGAACGCATAGACACGGTCCCAGGCGGGGAAGTCGGCCGGGACCGCCCGCCACTTGACGCCGTTGTCGAGGAGGTAGCGGACTGCGTCGAGCATGACGCGGTGGCAGTAGCCTTCCGGCTGCCCCGCCCCGGCCCTCCAGCCAGGCCGGCACCGGCAGCAGCGGACGGACGGCCGCCCATTCCGCATCGGTCATGTCCGACGGATACCTGCGTGCTCGCTCGCCGTGATCGGCGGCATTGCCGTACGTGTGCGCGATGCAGTCACACGATGGGGCAGCGGGGTTGGACGCAGCGAGCTCGGACACGCAAAGCTGTGACAACAGGGTCTCCTGGAACTGCCCGAATAGGGTCGCACCCCCGAGCTGACCAAGAGGCCCTGTCTTCATGCCCGGACCACCGAAACATCACCCGACCCAGAACCCCGTTCGAACCCAAACGCTCCCACGATCGATAGAACAACGGGTTCTGATCCGGCCTGCTCGGCAAGGGCATGAGATCCCGGGCTCGCGGTAGTGGACTTTCGGCGGTGCCGCGGGGCGGCGGAGTTCCGTAGGGTCGTGTCCGTGAGAACGATGATCATCTCCCGGGTGCCGGCACCGGTACTGTCCGCAGGCCTCTTCATCGGCGCGATGGCGGCCGTTGGCACCGGTGTCGCCACCCTGTGGTGGGGCATACCTGCGGCGGTCTGCGCCTTCCTCGCGGGCTGGCAGCCGGGGCGGAACCGGAGCACGGGGGCTGCCTTGGTCGGAGTGCTCGCGGCCGCCGTGGTGGCTGTGCTCCTGGTGCCGGCGTGGCTGGGGTGGGCGAGCCAGTTCGTGGGGTTGCTGCTCGTGGCTGCGATGCTGCCGTGGTTCGCGGGCCGGTTCCTGCGCCAGTACCGCGAACTGGTCCGGGCCGGATGGGAGCGGGCCGCGCGGCTGGAGCGGGAACAGCATCTGGTCGCCGAACAGGCCCGGTTGCGCGAGCGGACCCGGATCGCGCAGGACATGCATGACCTCCTCGGCCACGACCTCAGCCTCATCGCCCTGTCCGCGGGGGCACTGAAGCTGGCCCCTGGTCTGTCCGAGGACCACCGGGCCACCGCCCGGGACATCCGCGCCAGGGCAGGAGCCGCCGTCGACCGGCTCGGCCAGGTGATCGGTGTCCTGCGCGAGCCGTCGGATCCGGCTCCGGGGTCCGAGCCCGGCGCCGGAATCACCGAACTCAAAGGCCTGGTGGACCGGGCGGCCGCGGCGGGGCTCGACGTCCGGTTGCGTGTGGAGGGCGAAGCGGCGGCCGGCGACGCGCTGCCGGTCATCGAGCGGGCCGTGCAGCGCGTCGTCCAGGAGGCGCTGACGAACGTTGCCAAGCACGCGCCCGGGCACCAGGCGACCGTCGTCGTCCGGCACGCGGAAGGACGGACCGAGGTCAGTGTGACGAACGAGCCGGTGCCCAGCGCGTCTGCGGCCCACCATGGCCGTGCCGCCCGTACCGCACCAGAGCCCCGCGCCTCGGCACCTGGCGACGGCCACCACTTCGGGCTCATCGGCCTGGACGAACGCGTACGACTGGCCGGTGGCACCTTCACATCGGGTCCCGAGGGCGACGGGTTCGCCGTCCGGGCCACGCTCCCGCACCGTCCCGGGTCCGTGCCCCCGCCACGTGGCGCCGAGCCCGGCGATCCAGGTGCCGTACTACCTCCTGAGCACCGCAGTGCCCGTCGCCGGCTGGGCCGTACCGCCGCTGCGGCCGTCCTGGTGCCGCTGTGCACCTCCGCGTTGCTCATCGGCGGGGTGCGGGTGTGGGACACCATGACGGCACGGCAGGCGGTACTCGCCCCGCAGGACTACGCCCGGCTGCACGTCGGTCAGCCACGCGCGGACATGGCGCGGTATCTGCCCGAGCGCCAGACCACGCGCCGCCCGGCCGCGCCCACGCCCGCACCGCAGGATGCGGCCTGCGAGTTCTACGTACAGACCGCCGACCCGTTCGACGACCGCTCGGGGGACATCTACCGTCTCTGCTTCCGGGCCGGACGCCTGGTCTCCACCGACAACTACACCGGGAAGGACGTCCGATGATCCGGATCCTGATCGCCGACGACGAGCCCATGATCCGCGCGGGTGTCCGCGCAGTCCTTGGCACCGATCCCGGCGTCACCGTCGTCGCCGAGGCGGCCGATGGCCACCAGGCGGTGGAACTCGTGCAGCGCCACCGCCCGCAGGTGGCCGTTCTCGACATCCGGATGCCCGGAACCGGCGGCATCGAGGCCGCCGCCGAGATACGAAGGACCGTCCCCGAAACGGGGGTTGTGATGCTGACGACCTTTGGCGAGGACGAGTACATCCTGCGCGCCCTGAGTGAAGGCGCCACCGGCTTCCTGATCAAGTCCGGTGAGCCGGAGGAACTGATCGCCGGTGTCCGGGCAGTTGCCGACGGTGCCGCCTATCTGTCACCGAAGGTCACGGCCCGCGTCGTCGCGCATCTCGCCTCTGGCGGTGTGGGAGCCCAAGCCAACCGCCGTTCCGCGGCCCGCGCCCGCGTCGAGGCCCTGACCGGGCGGGAGCGGGAGGTGCTCGGCTTCCTCGGCAGCGGGTTCTCCAACGGGCAGATCGCGCGCCGCCTGCGCCTGGCGGAGGGGACGGTGAAGGCCCACGTCAGCTCGATCCTCGCCCGCCTCGGCGTCGACAACCGGGCCGCGGCGGCGGTGGTCGCGCACGAGGCCGGCGTGGTCCCGGTGCCGTCCGACCGGCTGCCGTAGGTGGACGGCTGACACCGCCCGCAGGGCAATCGGCCGTACGAGGAGCCACACCGTCATCACGGCCGTCGCGCCGAGCGCCGCGCCCGCCAGGACGTCGTGCGGATAGTGCACCCCGACCAGCACCCGCAACAGAGCGGCCGCCCCGGCCACCGGCAAGGCCAGAGCCGCCAGCCGTGGCCGTATCAGGACCACACCGACGGCCAGCGCGACGGCGAGGGTGGCGTGGTTGCTGGGGAACGACCAGTCGCCTGGCGCGGGACACTGCGCAAGGGCCGCGACCCCTGGCAGGGCCCGGCACGGACGTTCCTCGTCGACGAGGAGTTTGAGCGCCTCACTGACGGCATAGGCGACGACGGTCCCGGCGGCGGCCACGGCCACCCCGGCCAGCACCGCCGCATCCCTGCGGCGCAGGGCGCGCCAGCCGACCCAGGCCAACAGCAGGCCCAGGAACAGCAAAGTGCCCTCACTCGCCCCTTCCAGGACGGTCTCAGCCCACGACGGCCCGTCCGCCACGCTCCCAGTCAGCGCCCGGTAGGCCCGCACCGAGAAACCCGCAGTGCCGTGCGCCGGCTCGTTCGTCCCCAGCACACCGCCGGGCGCCAGCCTGACCACGGCCGCTGCCCCTACCCCGGCCGACGCGACCGCCATCAATAGCCGTCGGCCCCATCCATATCGCTTGATCGAATCCATGCTGCCGACGGTAGGAACACTGCAGGCGGGGCGCCCTGGCCGAATGGCAGCCCGGTACCCCGACGATCGTCAGGGTTGACCGGTACAGGCTGAAGGGACGGGACTAGCCTCGGAGACCCATAGGCCCTCACGAGGACGTGATCGCCATGCGGCAGCGGCTGCCATGGGCGGTGGTTCGGCTGAGTAGCTCGCCTCCTCGCCCGTCGGAGGCGAGCCGTGTAGATGTCGGCAAGCTGCTGGCTGGAAACGCTGCCGTTCCATACGACGAACGCGCCTCCGTCGAGAGGCGCCGCTCTGGCGGGTTCGCAGGCCCTGCTCTGGCCTCCCAACATCCCGGCGAGTTCTGCCCGGTCCAACGGTCAAGACCACAAACGATCTCAAGGTGACAAGAACGACGCACCTTCGGTGACAGCAATCCTGCTCACGCCGCCTTGGAGGGCGGGGCAGTTGTCGGGTGACAAGTTCCGTGCTCAGGCACACCCTCCGGCCGACGCCTCGCCACTCCACGAAGTCGGGGTCGGTGAGGTCCACGTCGTCGGCGTTCTCCAGCCCGGCGGCCGCGAAGAAGACCCGGATGTCGGCCGGTCGGTGCGCGACCCCGATGGCGACGCCGTCGTAGCGCACCCGGCGCCAGCCCTGCTCGTCGGGCGGGTAGACGATCAGCTTCGCGGACATGCGCCCAGCCTGTTCCCGTCGCACCCCACCGGCACCCGGCCGCGCGCGAACGGGTGAGGTAGCAGAGCCTGGCCCCCTGCGGACAGCCCGCACCGGTGTCCTCGGCCCCGGAGTACGTTCGGATGTACGGGGTGCGGCCCTGGCCGCCGGGGCCGCGACCTGAGCCGGTTCCCCCGTGCGGGTGGACCCGGGGCCGCCGGCGAACCGGTCCGGTCCCACCGCCGTCGCAGGGCTCATGAAACCGAACGAGCAGCACATCGCGGAGCCCGGCCTGGTGGTCCTGAACATCACCGGCGGGGACGAGGACACCGTCCGGGCCGTCATGGCCGCGCTGGAAGAGCGCTGGGCCACATCAGGCGTCGGCCCGGTGCGCCGGGATCCCGGCGAGCCCGGCGTCCGGGCCCGGATCTACGCCGACGTCCTGCGCCCGGGACGGGAAGCCCCATAGCCACAGCCCCTGGGCAAGCCTCCTCGCGGGGGCTTGCCCAGGGTCGCCTGGGGCTTGCCCAGGTACTCAGGCTTGCCCGGCCGCCGGAGCCCACAGGGGGTGTCCGCGGCCGGTGCCGTGGCAGTGGGAGCACAGTCCGCGGCCGGGCGTGCTGTGCGCGTCGATGGTGGTGACGGCGTCGCGCAGGAGCTGGGTGAGGCCGTGGACGTGGGCTGGGTGCAGCGTGAGTTCGTCACGGGTGCCCACCACGATCTCCAGCGTCTCCCCGGGAAGCGCACGGCGCTCGTCCGTTTCCAGGGCGGCAGGGATCAGATTCGCTACCAGGTTGTACAGGTCGGCCATGGTCTCTCCGCCGGCCAGCTCCACCCGAACCCTCCAGAGGAGGTCCGACCGTGTGAGAGACAGCAGCACGTCCGGCGTCAGATGGGGAAGGATGCGGTCGGGCGGTTCGGGGTGGGATGCGTGAAGGCGGGTGAGGGCGTGCCACATGTCGTCCGGATCGTGGCGCTGGAGTCCGTCCATGTCCTCTTGCAGCGTGTTTCGTGTCATGGCTCCGGTCTACGGCCAGCGAGGGACGTCAGCCGGCTTCTAGCCGCCGCGTCCCGGGCGGTGGCGCCACGACCTCGGGAGCCGTCCCGTCACGTGGTCCGGACGCTGGGCAAGCCCTCCGTGGCGAGGGCTTGCCCAGCGGAAGCCGTGACCGATCGGCGGCCCGGGCGTGACCGCAACTCCAACCCGAGGCGGTGACCGCTCATCGGTCACCGTCATCAGCCGGGGCCTCACCGGAAGCCCTGGGATGCCCGTGACCGAATCCGGCTAGCGGGCCGAGGTGGGCAAGCCGGTGCTCGGGGGTGGATTGCCCAGGCTCCCCTTGGGCTTGCCCGGCGCCGGTCAGCGGCCGACGGCTTCGGGGTAGCGGGCGCGGCGCTCGTGCGGGTCGTCGACGCCGATCTCGTACCAGAGCTCGCCGCGCTGGAGCCGGGGCAGGGTGTTGGCCCACACCGCGATGGTGATGCCCTGCACGGCGGCGGTGAGCGCTTGGAGGCAGTTGTCGAGGAGGTGTTCGGCCTTGCCTGCCAGGACGACGTGCAGCCGGGGGAAGGTGGTGGAGCGGGTGTAGCGGTGGCGCTGCCAGAACGGTCGACCGGCGACGAGGGGCACCCGCAAACAGTAGACCTGTTGCTGGACCGTGGGGTGGACATCAACGCGGTGATGAAGCACAAGACCGCCCTGGACTGGGCGGTCGGGTTCGGGCAGGAAGAGATGGTGCACCGCCTGCTCGGCCGCAGTGCCATCCCCTCGGCCGCGACCCTGGCCGCCGCGCGTGAGTATCTCGTACGTCATCCGGAGTGTCGGCGGAAGACCGAACGCATCGCCGTCGCCCTCCTTGCTGTAGATGTCGTGCCGGGCACGGACCAGGAGCCCGGGACGGGCGCCGGGAATCTGGCGTAGCGATCGCCCAGGGGGCACCAACCCGGCCCAACTTCGCTGTCACAGAACCACCGGTCGTCCGACTTCAGTGGCAAACGAGCCAGCTTCGATGGCACGGGACAACCCCGTCATAGGTCAGCCGCGACCTCACCGGGAAGCCAGGAGTGGGCCGTGACCGACTCCGCCGGCCGACCGAGGTGGGCAAGCCGGTGGTCGGGGGCGGTTGCCCAGACTCCCCTTGGGCTTGCCCAGCGTGCGTTGTGGTCAGCTGCGACGGCGGAAGAAGCCGCGGTCGGGCCTGCCGGGCTCCCGAACCTCCTCCGGGGTCCACTTTGGTTGCGATTGGGCGTCTGCTGGGTTGTCACCCACTCCTGCTGGAATCATGGACATGACTAATCATTCTCCGGGGGGCACGTGCAATGAGCGGTTTAGAGGACCTCGCGTCCGGGGCGGTTGATCTGATGGCCGCTGCTTCCACGGCTGCTGCGACGGGCATGGGCAGCACGGCTGCGACTGCGGTCGCGGACATCGTCCGAAGCCGGCTCAGAGGAGCCGGGCATGACGCGACTGTGGCGCAGTTCGACGCGGCTCCTCAGGAGCCCGGGTCCCAGACCGCCCTCCGCTGCGCTCTCATGGCTATCCTCACGGCTGATCAGGCCTTGATCGTGCAGCTCACCGATGCCCTTTCGGCAGCGGCCGAGGCAACCGACACGGTTCCCCCGCCACCGGTGTACGTCGCCTCCGGTGGAGGAGTCACCGTGCAGGGGACGGGCAACAGGCTTCGGGGCGACTTCGCCGGCCGGGACCAGATCATCCACAACATCCGCCACGGCGACGCCAGGACCCTCGTGGTCCTGGCCGTGGTCGCCATCGTTCTCGCCTTCGCCGTGTACGGCGGCGTCCAGGCCGTCGGAGGCCTGAATTCCGGTGGGGCGAGCGGACAACCCGGAATCGGTGCGTCTCCCAGGGGTGCGACCGACCGGCAGGGCGGGACCGGCACATCGCCATCGGCTCCGAAGAACACCGTGCTGTGGACGGTCCCCAAGAGGCCGTGGCCCTTCTCCCCGCCCGTGGTCAGTGGCGGCAGGGTCTACTACCTCGTCTCCAACGAACCTGCTGGCATCGAACTCATGGTCGTCGACGCCTCAACAGGCGCGGTGGTGCCCGAGTTCACCGCGAGACTCGACCCCAACTCCCTACCCGGGCCCCTGACGGTCGCCGACGGGCGCTTCTACCTCGTCGACGACAACGGCGTTCTGTACGCCGGCGACGACAAGCGGATTCTGTGGAGATACTCCACAGGCGCCAAGATCCTGAGCCCCCCGAAGCCGACGGTCGCCGACGGCACGGTCTACTTCGGTGGAAGTGGAGTGAGCCACGAACTGCACGCAGTGGACGCCACCGCCGGAACGGAACGCTGGACGTTCACCGCGAAGTCACGCATCTCCACGGCGCCGGCCGTCAGCGGCGGAGTGGTCTATGCCGGAACCGACGACGGTGACCTCTACGCGCTGGACGCCGTGACCGGAAAGCCTCTGTGGACGTTCCCAGGAGGCGAAGGCTTCTTTCACGGCGCTCCCGTCGTAGCCGAGGACACGGTCTACATCGCTGGGGACAAGGGGACCATGTTCGCGGTGGACAAGACACGTGGCACGAAGGTCTGGACGTTCCACGCTGAGGGCGACGCAGAAGGTCTCTCAAGGTATCCCTTGATCTTCGGCAACACGGTCTACTTCGGTGGCGACAACAAAGTGTTCTATGCCCTCGCCGCGGACACCGGGACCAAACGCTGGTCGGTGACGACCGGCGGATCCCTTGCCCGGTCACCCGTCCTCGCTGACGGCATCGTCTACTTCGGCATGTGGTTCGGCAAGCTGTACGCCTTCGACGCGGTCACCGGCAAGGAAGTCTGGTCCCACACAACCGAGGGCGAGTTGCCGCAGGACCCCGCGATCGGCGAGGGCACCATCATCATCGCCACACGGAATGAGAACAAAACCGAGGGACACCTGTACGCCCTGCGCCGCTGAAACTGCGGAACCGGCAGACCCTGCGCCGCAGTCGCCTCTCGTGGTCGACGGTCGCGATACGTCCGGCCGGGAACGGATCAGGTCCACGGTGCGCTTGTCCGCGTCCGAGGGCAGCGCCCGGCCCCACCCGGCACAGCTTGTGCACCAGGTCGAACATCGTGCGGTCCAGTCGATGGACGATGCCCCCGGCATCGTCACCACAGCCAGGCGTTCGAGTGCCGCATCCGGGACAGGGCGCGGGCGTCGCGGCGGCCGGCGGCGCTGCCGATGCGGTTCTGTCGGGGCCGGGGCCGGCGCGCCTGGGCACCGTAGAACCGTCGGACACCGGCCGCCTTGAGCCGCTTGCGCTGCTTGGCCAGCTCCTCCTTCTTCGCCTTGATGGACTTCGGTTTCCGGGGCCGCTTCCAGATCGGCTGCCAGGCTGGCGGCGGCGCGTACGCCTCGGCGCGCTTCTGGGCGGCCTCCTTCAGCCGGGCAGCGACGGCTTCGATCCTCGGGTCCGCAGGCGGCGTGGTGGTCATGCGACTCCTCCGGTGGGTGGTGTCCGGCCCGGCGCGGGCTGGACAGGCTGCTGGGGGCGCGGCGGCGGGGCCGTCGCCGGGGCGGGCTGTGGTGCAGGGCGGCGGGCGGCGGCTCGCTCCCGGATCCCGGCCTGGAGCCGGGCGGTCATCTCGGCGGCGGCCTCCAGCGTCCGGCTGGTCTGCTCCACCGCGACGAGGTCCGTCATCGGCTCCAGGTCCCGGCTATCCCTTCGCCCCGGGCGCAAGCTCGGGCGAGGGCTCGGAGTGGTCGGCACGGTGACGGTGCGCGGCCGGGGCCGGGAATTCAGGCGGTCCGCGCGGCGTAGCGCGTGGACGCGGGCGGTCAGCGCCCCGGCGGCGAGACGGGCCCGCTCGTACGGGGCGGCGGACCGCTTGCGGGTCAGCGCGCGGAGCACGGCCTGGTCCTCGGTGTCGTGCGGGTACAGGGCGCGCAGGTCAGCGGTCAGCATCCGCCGGCTGGCCGGGCGGGTGTAGCCGTCGATGGCCGCCTGGACTATCTCCTCGTCCAGGCCGGACCGGTGAGGTCGGCCTCGCAAGACGTAGGCCAGGTGACGGCGGGCTTCGGCGAGGAGGTGGTGGTGCTTGAAGGCGCCGCGCATCACGTACACCACGGCGGCGACGTTGACCGCCGCCAGCGCGACGTCGACGACCGGGCGCACCCGCGCCCATATCGCCGCGGCCGCTGCTCGGGCGCGCTCCGCCAGCCCGGCGACGACGTCGGCTCCGTACGCCCGGCTCGCCGACTCCCGCCAGGCGGCGCGCAGCTGAGAGAGCGAGCGCAGTTCCTTGCGCTTGGGTGAGCGGGTCTGGTCGGCGGCCTGGCAGGCCAGCGCGTAGGCGGCTGCTCCCCCGGCGCATGCCCCTGCTGCTCCTCGTACTCGGCCGTGAGGAATGGCAGCGCGTCCTCGATCTGCTGGCGGCGGGTCGACTGCCAGCCGATGAGCCGCTGGTCGATCCCGACGATCTCCATGACCGGGCGGCGGTCGGGCGTCACCTCGCGCGGCTCCCACGCCCACCCGAGCCGGGCGGACACCTCCTCCATGAAGTACAGGGTGTAGAGGGTGTCGGCTTGTGCACGCTCGGTCATTGACCGGGTAGCTGTACGGTCCGCGGATGTTGAGACAAGGGGCCTGGTCAGTCCACTACAGCTCGCGGGATCTGCCGCAGCCTGAGCCGCAGCCCTGGCACCTGCAGCTTTCCCCGGATGACTGGGAGTTGCGGCTCGATGACCTGGGCATTCCTGACGGCACGCCGTACCTGTTGTCGCCGTGTTTCGTCTACGACACGGATCTGAACTCGTACTTCCATCAGGTGAATCTGATGGAGGGCCCGCTCTTGCCGGTCTACCTAGCCAGATAACCCGCACGCAGTCGTTGACATCTACTCTGCGCACCGCAGACGGCACCTCCGCGCTTCCACTGACACCCACGCTGCGCCTACCAGCAGAGCCACATGTTGCGACGCCATCAGTGCAGATGGGGACCTGTTTCCCGCCCCACTGTCGGGCGACACGAGAAGGTCAGTGGTCGGCGACATGGCGTGTGTCAGTGCTGTGCCGCTTCTGGATCTTCGTGCTGTCGCGAATGTGGTGCCGACCGTCCCCGCATGGCCCCTGCGGTGAGGGCGGGGCCGTATCCGCGCCCACGGCTGACAACCACGCTGGTAGTTACGCGATTACGAGCCAGGAGCCCGCTCATGCCTACGCCGTAGCCACGGAATCCGAATGCGTCGGCCCCACAGCAGTGGCTCTCCACCCGGCCGAGCGAGAACGCCACCGCGTCCTGGAGTTCCGCAAAACCACAACGTGGCGCTGTTCCCTACGAGGTGCCAGCGGAGGTTGAGAGCCACTACGGACTGCACGAAGACCAACCCGGAGTCAGATGGTCGGAGCTGCACCACTGGGCCTCCCATACCTGGCGCCAGGACGGTGACCGGGTACGACTGCCACGGCCAACGGCGCAGCCTGTAGCGCATGCGTACTGCGTTGAACACCCAGCACGCCCCGAACAGCAGCGCGCTGAGGCTCACGACCCAGAGACCGGCAATGACGGAGCCAACCCATTTCGCGCCCGCTTCGTCAGCGGTGATCCCGATCCACGGGCTAACGACGGTCCCGACCGCACCACCGCCCAGCCAAAGCCACGCAAAGCACCAGTACCGCTTAAAGCTCGTCCGCGTCTCCTCGTGCTTCCAGGCAACCGTCTCCATGCGGACTCCCCGGTCCCCCGAACTCGATGCCCTGTGCCGTCTGCTGCCCATTCCGTCCCCGGTCAGTGTGGCCCCGCCGCGGATCACTCGTACCACCTCAACGCAAACCGCGCAGGCGAACGATTCTGGTGACCATCGTCAAACTACACCGCGACGCGGGACATGATTTCTGGCAGGTGCATACAAGGTTGGCCAGAGGCTTCGTGAACACCCCGGCCATAGGGAAGGCAGGCTCTGCGTGATGAGGAAACAGGCGCGGACCGAGTGGTGGGAGCAGTTGCCGGTGGGGATCCGGGAAGAGATCGGCGGGTACGTCCTTTAGGACGCCATGTTCGCGACGGTCAGGCTCGTGGTCGACGTCGGCCTGGCCCGGGAGCGCCCGACGGGTACACCGCCGCCCCGCGGCTCGACATCCTCCGGCCCGACCAGGCCGGCGCCGTCACCGGCCGGACGAAGCCGCACGCATCCGTCCGCGGCCCGATCCAGCCCCTCGAAGCAGAGGTTCTCCTGCGGGTCTGGATCGGCGGCGGAATCGCCCCCGGCGACGCCGCCCAGCGGCAGGCCCTCGAAGACCTCGCCACCGCCGATATGGTCACGCGCGGCGACATCATCGACGTCCTGCCCGATCACGTCGCGTACAGCCTCCGGATGCTCTCCGAGCCGTCACCGACTACTGACGCACCTCATGTCGCCGACCACTGACATCTCGTGTCGTCTCTCGCTGACGTTCTGACGTCGTCCGACACACCCGACACCCGCCAATCTGGAGGTACCCTCATGGACCACAAGATCACAAATAGAAGTACTCCCGGTATCTCCGATACGTGATCATGGTTCGCTCGGCGGACGAACTACAGCAAAAGGGGGCGGGCCGGGGTGGGGTACGCGACGCCGATCCGCGCGCCTGAGCAGGTCGAGTACCGGCTCGCCGAGAACTGCGGCTGCGACCAGAGCGTCGATTCCCAGGTCGAGTACCGACTCGCCGCCGCGAACGACCTGCGTTGGATCGGCAGCTGGCGGCCGCGGCCTGGCCGGAGTCGGCGTCCTGGTCATCGACGAGGCCGCAATGGTCGACGACCCGTCTACCCGGCCACCGTCGTCAAGACCCTCGCCGACTACCGTGCCGCCCTGCCCGCGTTCCGGGAGCGCCTGGAGAAGGCCGACACCGAGCGGTGCGCGTACCTGACCCAGCAGGCCGAAGCCCAGCGCGGCAAGCAGGCCAAGGCCATGCAGAAGGCCAGCGGACTGCGCGAGGAAGCCGTCACGCGGTCCGGCCTCACCGACGCGCAGAAGGCCACCGAGATCAAGCAGCGCACCGACGCTGCCCGACAAGCCCGCGCCACCCAGGCCCAGGCCGCCGAGGCCGCCCGCCAGGCCCAGCGGTACGAGGACACGAACCGTGCCTACCACCCGCCGACACCCGACCAGGGACGCGGCAGCCGTTTCGGGCTCCGAACAGTCATCGCCACGGATGGAGGCCGGGAAGACAAAGAAGAGGTGCCGGGAGTCATGTCCCAGCACCTCGCAATATCGGAAAGAACCGCGATCGACCGTCACCTGCGCTGGCGCCACCGGAGTCGGAGGGACAGCAGGCAGATGCACCCGAGGCTCAGGCTGATCCCCGCACCCATCGCGATGCGCGTGAGAACGGACATGGGCATGTCGATCATCGCGGTGACGCCCGCTCCGACACCCGCCGTCAAGAGCAGGATGACCGCCACCTTGAACCCGTCAAAGCGGATCAGTGCGGCGATGGCCTTCATCGCTCGGACCGTCACGGGAGGGCGCTCAGTGAAGATCTGGTCGGCAAGGCGGGAGCCTTTCACGGCCAGGGACAGTGCGAAGGTGACGGCCTCCGCATACCTACGGAAACGCGACGCCCAGGTCGGCGTAGGCCCCTCCATGATCTTCTCCACGTCCGGACACCAGTCCTCGGTGTAGGACCGTTCCCAATCCTCGCGCTGCATGAAGAGTCGGGCTCCGTAGAGGATGAGCACCGGAAGGCGGCCGGCCTTCCGATAGGTTTTCGCCCTGATCCACTTAAAGACAATCCCGGCCACGAGGAGGGCGACGCCGACCACGACGGCGGCAACCCAGGCGGGCCGGTCCACGCCGAGGAGCGTGTCACTCATCTTCTCGACCATGGTCATCTGCGTGTGGGCCATGGAGGCGGAGGTGGGGGCCACCTCGGCATGGAACGGCACCATGTGTGTCTCCTTAGATGATCAGCCGGTTGCGCCGGCTGTGTATCCGGGGATCGGCGGGATCGCCGACGCCTTGCGCCGCTGGTCGGCACCGCGGAGAGCTGCCTCATGGCGCAGCTCCGTCATCGCGATCTGGGCTCCCCGGATCCCCTCCGGGGTGATCTTGAAGCTGCGGCGGCGGCTCCTTCCTGCCTTCTGCGGGTCGATCGGTTCCGGCGCCGCGGTCAACCACCCCGCACGCTCGAACCTGTAGATCACCGGGTACGTAGTCCCGGAGCTCAGGCCCGTGATCTTCATCAGTTCCAGGCCGTACCGCGGCCGCTCGGGGTCTTGGAGGAAGGCGTCGAGGATGGAGCATGCCTGGCTCGTGATCACAAAGCGGCTGCTTTCACCCTTAGGCGCCACGGATGCGACACCGACCGCGGGGGCCGTGCGGTGACGCTGCTTCTGGCTGGTCGTTTTAGTCATGTACGGGTCCTTTCGAATGGCTTAAGGTCGCTTGCGGTATCTATTGCGGGATACCCGGAAATCGACCTCTGTTTCGAAGTGTGCGCCGTGCATGCCTGTGGCGGAAGAGGAGGCTGAGGATGAGATTCCGGAACGGTAGGCGTTGACATCGCGGGTTTGGGCCTCTGGCATCGTCACCGACACACTCGGCCTTCTCCTCGCAGTGTTGGTCACCGCGGCGAGTGTGCAGGACTCCGTTGCCGGCACCTCACTGCTCGACCAGGTCGCCGCCGAACACCCCCGGATCCGCAAGGTGTGGGTCGACGGCGGTTACCGCCAGCACCTCGTTGAGCATGCCGCCAGACTCGGCATCGACATGGAGATCACCGCCCGCAAGCCCGGGACCAGGGGATTCAGCCCCATACCCAAACGGTGGGCGGTCGAGCGGACCTACGGCTGGCTCATGCTCCACCGCCGCCTGGCCCGCGACTACGAAACCCTGCCCACCCGCTCCGAAGCCGTCATCCACATTGCCATGACCGACCTCATGGCCCGCCGGCTCACCGGCGAGAACACCATCTCCTGGCGCGACCCGAAGAAGACCACAGAACACCCGATTCCGGGATGAAATATCGGGTGAAAACGACCTCTTAGCGCAAGGCGCGCCGCGAGTACGAGAACCGCGTCACCGAACGAGGGCGGCGGCGACCCTGGCCCGCAGGGGCAAGGAGTCGTCATTGAGGACCCGGCGGAGCATTGCGAGTTGGGGGTGCCGTCGAAGGGCTGGCAGCGTGCACGGTAGACCGCGGGCACGGCGCTACCGCGCAGCATGTAGCCCTGGACGCGTCATACGCTCACGCGCGGTCGATCGCTGTTCGGCTGTGCACCTTGAACTCCGCACGGGCCGACCTCCTGGGCCGCTGGGTGGCAGCTTCAGTGACAGAAGACATTGGCCAGCCGTCCGTCGATAGGAGCATTGCCTCGGGAAACGGCACTCTCTGCGAGAACGCAAAGCTGTGCGGGGGTGAGTCCCACCAGGTCGCGGAAGTCACGGTTCATGTGCGCCTGGTCGTAGTAGCCACACAGAGTCGCCCGGTCAGCCAGTGATCGGCAGGCTTCGGGCGGCAAGGTGAGCGCCCGTTGAAATCGCAGGATCCGGCTGACGGATTGCGGTGGCAGTCCGATCTGCTCGCGGAAGAGCACCTGCAGCCGCCGGCTGCCGCGGCCCGTGGTGGCAGCCAGATCTTTGGCCGAGAGCTGCCCGTGACAGGCGCGCAGCTGGCTCCATGCCTCGGCAACGACTGGCGAGGGCGGCGGAGCGTCCACCATCCGCCGCGCAAGGGCGTTCTCGATGACAGCCCAGCGCCCTTCCCAGTCCGGCGTCGCAATGAGCTGCTCAGTGAGCCTGGCTGACCAGCCGGTACCCAACACTTCATCCGGGTGTACGTGGTCGTTGGCCAGGTGGTGCAGCGGCAACCCCAGGCACATGTACGCGCCGAGCGGAGTGAATTCCACCTCAACCGCCTCCGCTACCCCCGGGTAGCCACCCTTCACGGACGAGGTCCGCAGACCGGCGAGCATCGCATGCCACGTCGCACGCGACTCCGGAGCGCTCCGGGCCTCGTGGAACAACTGCAGGGGATCTCCCCAGCCCAGGATCAACGTCACGGTGGCCGAGGGAAGAGTGAGCCTGACCGGTCCCCGCCCTGCAGTGCGATGACCTCTGTACATCACGACCTGAGCCCGTAATCGCTCCGAGGCGCGACGCTCCACATACTCGCCCCTGTTCGTCGACTCCATGGACGTTTCAACCTCCGTCTGCGACCAGTGCCGGTGCGCGCGTCAGTCGACTCTCTTGAAGGAGTGCGCCTTTGTACAAGGCCACCGCCCGAGCTCCAGAGCAATCTGGACACACGCCGCCCTCGCCGAGGGCACATGAAAGGAGCAGCTATGCGTATCGGACGTATCCTGGCTGGCACTGTCCTTGGGGCGATGCTTGCGGTTGGGACCGTGGCACCCGCCCAGGCGGTCACGACAAGTACGCCCAAGGCGGCATCCGCCAGCGTCATGGGCGAGATGGTGTTCTATGACGACTTCTGGACGCAGTCCGAGTGCGTGGCGGTGGGGAAGCAGGGGCAGTCGGCCAGGATGTGGAAGATATACAGCTGCCAGCCGTCGCTCTGGGACTGGGACCTGTACGTCGGGTACTAATCTCGATCTTTCGTGACGGGCCCGTCGGCATCCGGCGGGCCGTTGCGGTTCCGTATCACCGAGGCCAGGCACCTCCGGTCTGCAAGATCATCCCGTGGCGGGTTTCTGGCGTATCTGGGTCATGCCCCTACCGGAGGCGAGCCGAGCACCGACGGCGGAACCGGGGCACTGGGGAGCTGCGCGGGGACGGCTGGGTGCGCACCGAGGAAGACGAGCAGCTGCTCACCCCGGCCACGCGGTACAGCACGCTGACCTTCGGCAGGCGGCCACGGCATGCTGGCGCGGCCAGGTGGAGACCACCCGGACCCGGGCCCGGCTGATGACCGAGGCCGGACTGCTGCACCGCTCCGCGGAGGCCCCGTGGGCGGGCACCACCGTGTGGACCAGCGAGCACGGAGTCCGGCATGCCGCCACCACGCTGAGGGCGCCGCGCTGGCCCGGGGAGCGGCTGCTGCACCGCCTGGCCGTCGCGGACGTCGGGCTCGCCCTGGAGGCGAAGGGGCACACCGTGCTCACCGAGCGGGAGATCCGCAGCGCGGAGGCCGTTGACGGCGGCGCCCAGGAGCTCCTGGAGGACCTGGGCCTGCCCGTGGCCCCTGGACCCGGCGCGGGGAGACGTTCGCGGTGCCGGTCGGCCCCCGGGCGCTGCACTGGCCGGACCTGGTCCTGGTACTGCCCGGCGGCACCCTGGGCGCCGTCGAGGTGGAGCTCACCGCGAAGACCCCGAGCGCGATCCGGCGGATCCTGCGGGCGTACGGACAGGCGCGGCGCCGTGTGCTGTACCTGGGCACCGAGCCGGTCGTCCGCCAGCTGCAGGGCCGCCCCGGCCCGGACGGGCGATGGGCCGACGGCGTCGCCCAGGACGTCGGACTGCTCCCGCCTGGAGGACCCGACCCGGGCACCGGCGGACTCCTGCGCGTCCAGCCGTTCACCGCCGGCGACCCCGCCGTCGACCGCCAGGCCGCGCGATACGCGAAGCGCCGCTGACAACTCCGGCGGCGGCCGCTGGATATCGGGCGTTGCCAGGGTGGATACGGCAGTGGATACGCATATCCACCCGCAGGATCGGCGCTCGCAGAAGCCGAACAGCGGTGTGCGGGACGGATGACGGGCGGGCGGAGGGCAGCGGGCGAAGCGGGTACCCCGGGTACCCGATGTGATGATCGTTCTCCCCGGGAGACGGCTGTCCGGCCGCCGGTGGGACCTCCCGCGGCTGCTGAACCGCGTGTCCGGGAAGGGGTAGACCTGTTAGCCCCAACAGGGTCAACCGCTGCTGAGCGGCGTTCTCCGGGCCTGTGATCAGGACCCGGGACCGACTCCGAGGATGCATCGGGCAGACACGGCCCCGGGATCCGCAGGCGGAGCGGACCGCTGCTGGAGAGTCTCCTCAGCGGCCCGCTCAGCGGCGGTGCGCCCGCGGACCGCACGCTCCTCCTGGACGTCGTTGCGAGGGACCGGCCCGTGCCCGAGAGGGCGGCGCATGATGCTCATCGGCGCAGTCTCGCAGCACCCTCAGGCGAGGGCACGCCCGACGCCAGCGCTGAGATGGAGGCAAACTGGGGGCCGCCAGAAGTGGGGCCAGGTGCCCAGGGGAGCATCCCTGACCTACAGGAGATCCGCGCCTCCGGCCGCATCCCGAGTCAGCCCACCACCGGCTGACCGCTCCCGCTACTGGTCGTTCTGATCTTCCCCGTAGGGGGGAGAGACGAGCCTGATCGCATCAAGGAGTCGTCTGCCCCTCCGTCACGCCGGCCTTGCTGCACTGGCGGCCGACCGCGAACAGCTTCGGGTCCTGACGGTAGTAGGGAAGGGGGCCGCTGCAATAGATACCTCCCACGTAGAGCACCTGGTACTGCTCGTACGGAAGCCGGGATGTCACCTTGAACGGTCGGCCAGCGTCGTCCGCAGTAACGGTGGTCGTCTTCGTGCCTACGCGGACGTGGAAGAGGACTCTGAACTCGCAAGCCTGGTTCTTCGTGGTGGTCTCGATCACGAAGGTTTGCTGTTCGCCCTTCTTCAGTTTGTACTCCTTTTTTGCGAAGGCCTTCGGGGAGACGACGGGTTTGTCGAGGTCGAAACGGACATTGGGAATGGGGCTTCCCCCTCCTCCCCCGGGGCTCTCGAAGAGAGTGCCCCGTAGCGCCGGCTCGCAGTGCTTGTCGACTAGCTCCGCGCCGGTCACGCTCGCCTCGTTCTTCTCGTCGTAGCCGCCCAACGTGATCACGAGCGACTGGATGTCTGCCAAGCCGACCGCACCGGTCTCCTGTACCCACGACTTGAAGTTCTGTCGCTCCGACAGCTGGCTGATGGTTTCGGCAGACGGCGTCATCGCGCCTCTGAAAGCGACGCTCTTCGACTCATCCCCTGGTTGGACGTATGCATCGTCCAAGCGCACCGCCGGGCCCCGAGCGTTCTGCCAATCCTGATACCGATCGACTGCGATGAACCCCAGGAGAGCAATGCTCGGAACCTGTGGATCGGCGAGGGAACGCGAAGGGCGTACCTTCCCGAATGATCCTTTGATGGTCTCCGAATAGGCCCGCGTTGCAGCGCGGGTTGGGAAGGCACGCGCGTGCTCAGCGTAGTCACCGACGACGGCTCGACCCAGTCCGGCTCCCTGATCGACGAAATCGTCCGTGAGGGCGCCCGCCGGATGCTCGCCGCCGCGCTGGAGGAGGAAGTCAACCAGTACATAGCCGAGTTGGCTGCCGAGACCGATTCTGCCGGCCGACGTCTCGTGGTCCGCAACGGCCACCATCAGATCCGGACCGTGGTCACCGCGGCCGGCCCGGTCGCGGTCAGGGCACCGCGGGTGAACGACCGCCGCGTCGATGAAGTGACGGGCGAGCGCAAGCGGTTCTCCTCGAAGATCCTGGCTCCGTGGTGCCGCAAGTCGCCGAAGATCTCCGAGGTCCTGCCGCTGCTCTACCTGCACGGATTGTCGTCCGGGGACTTCGTGCCCGCTCTGGAGCAGTTTCTCGGCGGCACCGCCGGCCTGTCGCCCGCCACCGTGACACGGCTGACCAGGCAGTGGAGCGACGATCACGCCGCCTTCCAGGCCCGGGACCTGTCCGACCGCGACTTCGTCTACGTGTGGGCCGACGGCGTGCACCCCAAGGTCCGCCTCGGCCAGGCGCACTCGTGCGTCCTGGTCCTGCTCGGGGTCCGTTTGGACGGCACCAAGGAACTCATCGCCCTGGCCGAGGGCCTGCGGGAGTCCACCGAGTCGTGGGCCGACCTGCTGCGAGACTGCCGCCGACGCGGCATGCGTGACCCCGAGCTGGTGGTCGGCGACGGCGCGATGGGCCTGTGGCGGGCGCTCGCCGAAGTGTTCCCGGCCGCACGGCCGCAGAGGTGCTGGGTCCACAAATCCCGCAACGTCACGAACTGCCTGCCCAAGTCCGCGCAGCCCGGGGCGACGAAGGCGATGCAGGAGATCTACAACGCGGAGGACCGCGGCCACGCGGAGAAGGCGATCGAGGCGTTCGCGAAGACCTACGGCGCCAAGTTCCCCAAGGCCGTCGCGAAAATACCGGCGACCGGGAGGAACTCCTGGTGTTCTACGACTTCCCGGCCGAGCATTGGATCCACCTGCGGACTACGAACCCGATCGAGTCGACGTTCTCGACGGTCAAGCTCCGGACCAAGGTCACGCGAGGTGCGGGCAGCCCGGCGGCCGCGCTCGCGATGGTGTTCAAGCTGGTCGAGTCAGCTCAGGCTCGATGGCGTGCGATCACCGGTGCCCATCTGGTGCCCCTGGTCCGCGCCGGGGCACGGTTCGAGAACGGCGTCCTCGTCGAACGCGAGGAGCAGGCAGCCTGATTGGCTGAAGGAGCCACCAGCCGACCCATGGCTGAGCTGGCCTATCCTCAGTCAGGCTGATTTGGGGCGGCGAGAGCTTGGCGCGACTGGACTACCGCGCCCAGCGTCCCATGGCCGGCGCGGTGCCGATCAGGCACTCGATGTCGGCCGGGAAGCCGGCGAGGGCGTAGGCGGTCAGGCGCAGGTGGCCCTCAAGGCAGACCAGGTTGTCCTGCCTCTCTCCGACGAGGATGAGCGGAGGAAATCGTTCACCTCTGATGAACGCGTGGGCCGCGTCGACGAACGGTTCGTTGGGCACGTCGAACGCCCGTAGCCCTGCCTTGATGCGTGCGGCCGCGTCGGCCGGCCGGCGGCTGCCACCCGACAGTTCGACCCAGTAGGGATTGTCGAGGTACCGCACGTCGGCCGCCTCGTCGGTGGACAGGAGTGCCCTGGTCCACGTGACGTGAGCGGGGAAGTTCTCGAACAGGTCACGGTTCTCGCCGTATCCGCGCGTCGCGGCCAGCAGAGCGCGACGTGCGAAGTTCGCTCCAGCGTCGGAGAGGTCCGGATGCGTCAGCAACTGCTCTGCCTGCCCGGCTACCGCCAGATGGGACCGGAGGTTCTGGCCGAACCTCTGGCTAGACAGCTCGCCGCTCAAGAAGCAGGCGACCATCTCGTCCTCATTGCTCACACCCAGTACCTGCACGACCGTCAGCATAGGATCGAACTCGGTGGGTGCCGCAGCCTGCTCGCACGTCATCTCGTTCACAGGTCTTGACTATTGCTCTTTCTCCACCCTGCCCTACCGTCTGCCCGGCGTGAGTCCGTTCTCGTAGGCGATGATCGCCAGGTGGACGCGGTCCCGGGCCTCGAGCTTGGCGAACAGACGCGCGACATGGGTCTTCGCCGTCGCCGCGCTGATCACCAACCGCTCGGCTATCTCACCGTTCGACAGTCCCTGTCCGACCAGTGCCAGCACCTCGCGCTCCCGGTCGGTGATCCCAGCGACGAGACTTGAGTCCGCGGCGGGCTCGGTGGCCGGTGCGGGGGTGGCGGAGGTTCCGGCGAAGTCGGCGATCAGCCGTCGGGTGACGCTCGGCGCGAGCAACGCGTCACCGGCCGCCACCACGCGGATCGCGTCCAGGATCGCGTCCAGGGCCATGCTCTTGAGCAGGAATCCGCTGGCGCCGGCGCGCAGTGCGCCGTAGACGTACTCGTCGTCGTCGAAGGTCGTCAGCACCAGCACCTTGGGCGGGTCCGGCTCGGCGGTCGCCTGCCGGGTCGCCTCGATCCCGTCCATGCCCGGCATCCGGATGTCCATCACCACGACGTCCGGCCGCAGCTCGCGCACCAGGCGCACAGCCTCGACGCCGTCGCCGGCCTCCCCGACCACCTCCAGGTCGGCGGTGTCGCCGATCAGGATCCCGAGCCCGACCAGCATCAGCGGCTGGTCATCGACCAGCAGTACTCGCACGCTCATGCCGGGAGCCTCGCAGCCACCCGGAATCCGCCCTCCGGACGTCGGCCCGCGCTGAACTGGCCGGACAGCAACGTCACCCGCTCGCGCATGCCGAGCAGGCCGAAGCCGCTCCCGCCGGCCGTTGCCGAGGGCCTCGGACGGCCGGGCCCGGGACTGTCGTCCCCGTCGTCCACCACCTCGATCCTCAATCCTGTCGGCTCGTATCCCACCGCGACCCGGCACGTCCGCGCACCGGAATGCCGCACCACGTTCGTCACCGACTCCTGGACGATCCGAAACGCCGACAGCTCGATCTCCGGCGGCAGCGGACGCCGCTCGCCCCGCCAGGCCACGTGGACCCGCACCCCGGCGTCGGCCGTGCGTTCGGCGAGCCGCGGGATATCCGCCAGGCTGCCGGCCGGCGCCAGCGGAGCGGCCCCCGGCATGGCGTCGTCCGGCTCGGCGCGGCGTAGCGCTCCGAGCATGCGCTGCAGCTCGAGCAGCGTCTGGCGGCTGGTGGACTCGATGCCGGTCAGAGCCTGCCGCGTCTGCTCGGGCTTGGTCTCCACGACCCGAGCCGCCGCTCCCGACAGCACCGTGATGATCCCGATGCTGTGCGCGACGCTGTCGTGCAGTTCGCGGGCGATCCGCAGCCGCTCGGCCATGACGGCGCGGGCCGCCCTCTGCTCATGCAAGGCTCCGAGGTACTCACGGCGTTTGCGATACACCCCCCCGAAGACCCACGCGACCGCGAACCACAACGCGAACTGCCCGGCCCACTGGGCCGCGTCGCTGACGGTCTCCCCGGGGTAGACGTGGATGTTCTCGACGAACGCGGCCGCGACGGCCGCGACGGAGCCGACGGCGGCAGCCTTCGGCCGCCGGACGGCGAGGTGCCCGCCCAAGAAGACGAGCAGGACGAACACGATCAAGGGCCGCACGCCGAAGAGGTCGCCGAGGACCGATTCGCCCAGGATCGCCGCGAAGACCGCCGCCGGCAGACGGCGCATCAGCAGAACCGGAAGGGCGAGCACGACGCACAGACCCATCATCTGGAAGGGCCCGAGGCCGGGAAACCGGAACAGGCCGGGACCACGACGGATCGACCAGCAGAGCATCAGCGCGTAGAAGCAGGCGGTGGCCAGTACCACGGCCCGGTCCGTCAGCCAGGTCACGCGCTTCGATGTCGAGAGACGCTGGAGAAGCTCTTCCATACGGAGATCGTATTCAGCGGCGTCGGCTCCGCGCGTCGCCCCGGGGATGTACGCGGGGTACACCCCCGGGCCGACGGCCTGGGGAACGGTGACATCCACCGGCCGACGCGACGGAGGAGCTGCGGAACCTAGCGTCGATCCCATGAAACGCAATCGCCGTATCAGCGCTGTCGCGGCGCTGGCGCTCGCCGCCCTCGTCACCGGAACCGGCACCGGGTTCGCCGCCACGACCACACCGTCGGCCACACCGGTGGCCACGCACGCGTTCGACACCGCACCGGCCACGGCCACCGCGCCCACACGGTCCTTCCAAGGCACCCTCCCCGCGCCGACCGGCCCCTACGCCGCCGGCAAGGAGGTCATCCACCTCACCGACGCGAACCGTCCCGACCCGTGGGTGCCATCATCCGGCCCCCGCCAACTGACCGTCACGATGATCTACCCGGCCGTCCCCGGGACCGGGACTCCGGCCCCTTACATGACCCTCGGCGAGGCAGCCGGAATCCTCCAGCGCCAGAAGACGCCGGCGAGCTCCGGCGTCACCCCGCAGACCCTTTCCAGCGTCACCACCCACGCCTTCGACGGCGCGCGGCCGCAGAGGGGCAAGTATCCGCTGGTGGTCCTCTCAGCCGCGCACGAGAACCCGCGCATGACGCTCACCGCGCTCGCGACCGACCTGGCCAGCCACGGCTACGTCGTCGCGCTCGTCGGCCACACCAACGAGGACAGCGGCGAGACGCTGGCGAACGGCCAGACGCCGCCGTGCGCGATCTGCGACAACCCGGCGCTCAACCTCGACTCCGTCGTCGCCAGCCGCGCGACGGACGTGTCCTTCGTGATCGACCAGTTGACGCACGGCAATACCGCGTGGCGCCTGGCACACCTCATCGACAAGCACCAGATCGGCATGGCCGGACACTCCCTCGGCGGAGCGTCGGCCGCCGCCACGATGATCGCCGACCCGCGAGTACGGGCCGGAGTGAACATGGACGGCACCTTCCACCCGACCCCGATGCCAGGCCAGATCAACCGGCCGTTCCTCATGCTGGGCACGGCCGAAAACCACTCGGCCGGCGGCCACAACACCACGTGGGAGCAGGCATGGGCCGCCCTCGGCGGCTACAAGGAGTGGCTGACGGTCACCGACGCCGACCACTTCAACTTCAGCGACCTGGACCTGCTTAAGAAGCAGGCCGGGTTCCCGACGCAGGGCCTCTCCCCGGAACGCGGGCTGGTGATCACCCGCGAGTACGTGACAGCGTTCTTCGACCAGACGCTGAAGGGGATCCACAGTCCGCTGCTGGACGGCCCCTCGCCGAACAATCCGGAAGTACTCTTCCAGCACTAGGCAGTGTCTGATGGCTCTTTGGTGAGGTCGCGGAGCCAGATCACGATGGCTGCGGTGGCCAGGGTGCCGTGGAAGATGTAGTCGCGTTTGTCGTACCGAGTCGCGACGTCCCGGTGCTGTTTCAGCTTGCTGATGCAGCGTTCGACGGTGTTGCGCCGGCGGTACTGCTCACGGTCGAAGGCCGGTGGGCGGCCGCCGGCCCGACCAAGGCGGCGGCGGTTCGCACGCTGGTCGTCCGGCTGGGCGATGGTTGCTTTGATCCCGCGTTTGCGCAGGTAGACGCGGTTGGCGCGGCTTGAGTAGGCCTTGTCGCCGCGGGCCCGGTCCGGCCGGGTCCGCGGACGTCCTGGCCCGGTGCGGGCCACGTTCAGGGCCTGCATGAGCGGGATGAACATCGGGCTGTCCCCACGCTGACCGGGCGAGGTCAGCCAGGCCAGGGGCCGGCAGCGGTCATCCGTCAGCAGGTGGACCTTGCTGGTCAGCCCGCCCCGGGAGCGTCCCAGGGCCTCACGGCCATCTCCGTCCACACGCGCGCCACCCCCTTTTCAGGATGGTCGGCCGGAGGAGCGTGCCGGGCTCCGGCTGCGTGCTGGTGGGCCCGGCAGGTGGTGGAGTCGGCGTTGACTGCCCACGAGCCGTCCGCGTCCTGGGCGGTGGAGTCGGCGCTGGCCTGCAGAGCGCGCAGGATCTTCGACCAGGTGCCGTCGGCCGACCACCGGCGGTGGCGTTCGTAGACCGTCTGCCAGGTTCCGTAGCGTTCAGGCAGGTCACGCCACGGAATCCCTGTCCGCGTCCGGTAGAACACACCGTTGACCACGGTACGGTGATCAGCCCACCGCCCACCCGGGTTCCCGGTCTCCGGCAGCAGCGGAGCTATGCGCTCCCACTGAGCATTCGTCAGTTCATGCCGACGCACCATGCCAGACCCCTGCCCAGAACAGGGATAGATCCACCATCCCAGGCAAGAGCCATCAGACACTGCCTAGCCGGGGTCCACGCCATGGCCGGGCTCGCCGACGATTGGACCGAACGCCGACAAACCTGTATCGACGTTCTCTGCGCCTACCTGCGCATGCCCTACCCAGGAATCCTCGCAGAGGGCACACCAGCCGACGGAGATTCCAACGGCCAAGCCAACCGCGAAGTCCGCCTCACTGTCATCCGGACAATCCGTGACCACCTCCTAACCGCCACCCCACAAGAGACGTCCTGGAGCGGATACGACCTCGACTTCACCGGCGCCGTGTTCGATGGCGGCGACTTCTCCAACGCCACGTTCTCCGGTGACAAGGTGCGCTTCACCGGAGCCACTTTCTCCAGCGGCCTGGTGAGCTTCTACGGTGCCACCTTCTCCGGCGGTTCGCTGGGCTTCTACGGTTCCACGTTCTCCGGCAGCGAGGTGCTCTTCCGTGGAGCCACCTTCTCCGGCGGCTCGGTGAACTTCCGTGGAGCCACCTTCTCCGGCGGCTCGGTGAACTTCCGTGAAGCCACCTTCTCCAGCGACGTGGTGAACTTCGACCGCGCCAAGTTCTCCGGCAGCGAGGTGGGCTTCTACGGCGCCACGTTCTCCAGCGGGAAGGTGAGCTTCTACGGAGCCAAGTTCTCCAGCGGTACCGTGAACTTCGACCGCGCCAAGTTCTCCAGCGGCGCCGTGAACTTCGACCGCGCCAAGTTCTCCGGTGCCACGGTGACATTCCGTACGGCACAGTTCGATGGCGGTGTCGTCGACCTGAGAGACGCGGCAACCTGGTCGCGGCCTCCATCCCTCGACGACGGCCTCCTAACCGCCCTACCCGCAGGACTGCTCCTGCCGGGCCAGCTGCCCAGGCCGAATCCTTGAAGCCTGGTGACACGTTCGTTAATGGCACGCCTACTTCGGCAATCTCGGCATGTGGGAAGACAGACCCGGCGGCCGGCCGCAGCCACGGCGACACGTCCACCGCGAGCACCAGGCGCCCGTCGGCGGCCCGGGGCAACGGGACCCCGACCAAGGCACGGCGGAGTCGGGCGACGTCGATCCGGCCTTGGTTCAGCCCGGCGTAGAGGGCGCCGTGTCCCCGACGGTGCTCGGGTGCGAGGGCCAGGTCCACGAGCGTGCGGACCGGGCCGTCGGTGCACAACAGGGGATCGCACAGCTCGAAGAGGGCGTCCCCCCGGGCGAGAAGAGACGTGTACAGCTCGGTACGGAACGCTGTCACCGTCCTGAACGCGTCTCGTTGAACCTCGTGCTCGACCTGTTCCACGATGCGGCCTCCATGCCGCGCCGACCTCTCCTCGCAGGATCAGCCTCCAGCCCTGCGGACACGCCATGAACAGGGCAAACCCCGAACAAGTTCGAGCCCCGTTCGGGGGCGGACCAAAAACGTCAAGCTCAGAGGTAGGGCTCTTGCTGCGCGGTGAGCTTCCTGGCCTGCTTGGAGCGCGCGGAGTGGGGTTCGCCGGGTGTGAGGCACCAGGCGCCGGCCTCCTGACCGCAGTGGGGCAGGGCACGTCGTACGCCAGCCACACGGTCCGGACCGCCTCGTGCTTCTTCTGCTGTTCCTGGAGTTCGGCGATGACGGGCCGCAGCCGGTCGACGTGCGGTAGTTGCCGTACGCGGCCGGCATGCGGTCCCCCGTCGACCACGCACTGCTGGCCGCGGTCAGCCCCGCACTGGGAGCACGGCCTCGTGGTCCAGTACGCGCGGCCGACCTGCTGGTGCAGCGGCACACGTTCTTGCGGCTTGAACGGCTTGGCCAGCCGGGGCGGAAAGGGCAGACACCGAAGGCGCGTACTCCACAGGATGAGCTGAGTCTGCCGGTGCTCCCCGAGCTTGCCGGCCTCGGCGGCTACCTGGAGTAACTGCTCGACCTTGGACCGCAGACGCCGCGGATCCTCATTCGCCGGAAGACGGCTGATGTCCTCCAGGAGCGTGTCCAGGCGCGCGAGCTTGGCCGCCTCGAGCGCGGCCAGGTAGGCGGCGGCCTCGCGGACCGTGCGTTCTTCCTCCTCGGTTCGGCGGCCCCGGGTGCCCGCCTTGATCTCCGCCAGGAGCGCCTTGATGCTCCCGGTCTTCTGAGCGGCCACGGCCTGATTCAGACGGGCGAACAGCTCCCGACGGGCCTCCGTCTCCTTCTCCACCGAGGCCAGGGCGCTGCGCCGGGCGGCGTCCAGCCGGCGCTGAAGCTGCGGGCTCACCCCGGCCAACTCGGTGATCTCGCGGCACACCTCTTCCGTCAGGTCGGTGGACACGGTCCGGCGGGCGTACAGCAGCCGGCGCCTCGGCTCGTGCGCCTGCACGTCCTGCGCCGACTCCTCCTGCTTCTTGCCCGGAGTCCACCGGGTGGAAGGGGGCGCGCTCCTGGCCTGGACGATCCGCTCGACCGCCGGGGTGGACAGGCCCCGGTCGGTGATCTCGCATTCGTCCAGGGCGAACCACTCGGTGGGCCGGGCGAACGCCTCAGTGCCGATCCGGACCCGGCGGGCGGTGCCTTCGCTGTCCAAGCGGATGCGGTGCACATACCAGCGGTCAATCAGGGTGTCGGAGTCCACCGTGGCTTTGTTCATGAGAACGGGTTCTGGCTCAACTTCTGGGCTCTGTCGCTAATTTGGGGGAAGTTGGGCAACTATCCGATGTGACGGGTGGGGTTCAGGTCTCGGATCTTCTTCTGCCGGGTATCGCGGTGGAGGTCGACCAGCTGGTGATGACGGATGCGGAGGTCCGGGTCGCCGTGCGGTCAGGGGCCGTGGCCGCGGCCTGTTCCGGATGCGGGCGAAGATCTTCGAGAGTGCACTGCTACTACCAGCGGACTCTGGCAGATCGTCCGGTCGCTGGTCGGCGTGTGCGGATCGAGCTACGAGTGCGTCGACTCGTGTGCGGGAACGAGCACTGTCCCCGTCGGACGTTTGCCGAACAGATACCGGCCCTGACGCATCGCCATGCACGCCGCACGGACGCTCTCACCGCCCAGCTCACCGACGTGGCCCTGTTCCTGGGCGGCCGGCCAGGAACTCGCCTGGTCCAGCGCATGACCATCGACACCTGCAAGGACACTGTGCTCCGGCTGATCCGAGCTCTTCCGCTCCCCTCATCGGGACCAGTGCCGCATCTCGGCGTCGACGAGTTCGCCGTTCGAAGGGGACGGACCTACGCGACGATCCTCATCGACATGGCAACCCACCGCCCGATCGACGTCCTGGCCGACCGGGCCGCAGCCACCTTCGCGTCCTGGCTGCGCAACCATCCTGAGGTCCGGATCATCTGCCGCGACCGTGCCGGCTCCTACCGCGACGGGGCCCAGACCGGCGCCCCGCAGGCCAGGCAGGTAGCCGATGCCTGGCACCTCCTGAACAACCTGGCACAAGCAGTCGAACGCGTCATCGGGCGGCATCGCTCCGACCTGCGACAACCCCTCACCTCCCACGACGACCGGAGCGACGAGGGCCCGGCCTCTGAAGGCCGCGACCGCGCAGAGCTGGACATCCACGGACGGCCACGGCCTCTGGTCGCCCGCACCCGCGAACGCCACCAACAGATCCACGAACGCATCGAACGCGGCGACAGCCTTCGCGCCATCGCACGCGACCTCCAGCTCAGCCGCGGCACGGTCAACCGCTTCGCACGCACCGCAGAAGTAGATGAACTTCTCCTCGCAGCCATCCACCGACCCACCCTGATCGACGACTACCGCCTCTACCTGCACCATCGCTGGATGGAAGGCTGCACCAGCGCTTCCGCGCTCGCCCGGGAAATCCAGCGGCTGGGCTACCGCGGCGACGTCAACACCGTCCGCCGGCACCTGAAGCCCTACCGCAACGGCGCGATCCCGACCACCGCCCCCTTGCCCCACCTGACCGTCCGCAGGGTCACCGACTGGATCATGCGACGCCCCGAGCACCTCACCGATGCTGAGCGAAAGGGTCTCGACGAGCTGTGCGAGCGGAACCACGTGCTGGCGACGACCGTCGAGTACGCACGCCGCCTGGCACTCATGGTCCGCGACCGCCACAGCGAACACCTCGCCCTCGATGTCTGGATCGCCGATGTCCGCCTCGACGGGCAACAAGAGCTCCGAACTCTGGCCAACGGCATGCGACGCGACCGCGCGGCCATCCAGGCCGTCCTCACCACGACCTACACGTCCGGAGCAGTCGAGGGCAACGTCACCCGGATCAAGCTACTGAAGAGACAGATGTACGGCCGCGCCAACTTCGATCTCCTACGGCGCCGCATCCTGCTCTCACCATGATCAAGAGGCCGCTACCCCCAAATTAGCGACAGAGCCCAAAAGTTGAGCCAGAACCGCCACTTCGGGAGGCACCGCTGTCCGGCGCTGTTCGATCGGTACTGGCACCTGTCACTCCGCTAAAGGAGGCCGGTGCGCATGTGCTGCGTGAGGTTGTCGTGGATCTGGCGTAGCCACGGGGCGCGGACGGCCGGCAGCCGGGCCAGGGTTCGTTGGAAGACTCCCCAGTCGATCCGGAACATGTCATGGACGTTTGGCGTGGGCGGGTCGTCGCGAAGGACGCCGTCGGGTATTGGACCCGATGAGGGGACGGGCAGTTGCGGCTCGGGGAAGACCAGCCGGAGCCACACCCCGAACGGCAACGGGACCAAGCGCGCCGGAGTGGCAGGGGTCCATGCCTTCCCGGTCTGCGGGTGGGACGGCACGAGGAGGATGTCGGCGCCGTCGTGGGCCGGCTGTCCCGGTCCGGCCAGGACGGCGCGCCGCCTCGGCCCGCCGGCCGGCAGCAGGGTGTCGAGGGCGCGTTGGAACATCTTGGCGGTCAGGCCGTCCGGCACGGCTACCGCCCGGCCGTCGGAGGCCACCAGGAGGTGGGCGAGCGCCTGCCCGGCCGCCGCCACCCACTGGGGGCTCCAGTGCCATCGGTCGCTCGCCCGGAACGGCTCTCCCCACGGGGGGATTGGCTCGGACGGGGGCACGCCATCCCCCTCCGCGAGCAGGTCCGCCCAGGACAGCGGTCCGGGGTCGGCGCCTTCGACGGGAAGGCGGCGCACGGCGTTCGGGGCGAGCCACACGGCCTGCCAGAGCGAGCAGTCGTCGATCCTGCTCGCCACGGGAAGACTGCAGGCCGCGCAGGCCATGTTGGGGCCGTCACCCCCGTCGAAGCCGCAGCAGGCGCCGCCGCGCTTCTCCGGGATCAGCACGGCGCCGCGGGTGTCTCCCGGTGCGATGACAACCGCGCCGGACACGCCGTCGGACAGGGCGTGGACCGGCGCGTAGATGCCGCGGGCAGCCGCCTCGTCCGGATCGATCTCCTCCCACCTTCGCCACGGCGGCCCCCAGGGCTCCAGTTCCACGGCGAACGTCCCCGATTCCATGAGCACCGGGAGCTGAAGCCCGTTCCCGTACTTCTGGCGAGCGTGGGCCGGCAGGGCGACCTGGGACAACGGGGCGGTCAGCTTGGAGCCACACCGCACACACACGAAAACGAACAAACGTCCTCCCCTCGGGAAACAGGGGCATCGTCGCAGCTCCGTGGCAGACCGGCCAACGTGTTTTCAATTCGCTGTGGGGCCGAAGCACAGCCACGACGCTGAGCATCACCGTTCGAATCCTCGGCGCGCTCTAGGGTCCGTCTTCAAAAGATCGTTCGATGGTGGATCATGTTTTCGTGATTCGTCGCCATGAACTGACTGATGTCGAGTGGGAGTTGCTGGCTCCGCTGATACCGAGTGCGGGCAGGGGCCGGCCTCGGGCGGAGGACCGTCGGGTGATCAACGGGATGGTCTACAAGATCCGGACCGGGGTTTCCTGGCGTGACCTGCCGGAACGTTACGGCCCGTGGAAGTCGGTCTACACGCGCTTCCGCCGCTATGCCATCGACGGTGTGTTCACCCGGGCACTGCAGCAGATCCAGGCCCAGGCCGACGCAGCCGGTGACATCGATTGGCTGGTCCAGATCGACTCCACCATTGTCCGCGCCCACCAGCACGCCGCCGCCACCGGCCGAAAAAGGGGGAAGCACCGGACGGACGAACCGGACGATCACGCCCTCGGCCGATCCCGAGGAGGCCTGACTGCCGAAATCCCTCTCGCCTGCGACGGCCGCGGTCGGCCCCTGGCCGTCCTGCTGACCCCGGGGCAACGGCATGACGGCGTCTGCGTGAGGCCTCTGCCCGGACGCATCCGAGTACCCCGCACCGGCCCCGGCCGGCCCCGCTGCCGACCGGACCACGTCATCGCCGACAAGGCCTACAGCTCACGCGGCTTCCGCGCCTAACTGCGACGACGCGGCATCGGACACACCATCCCGGAGAAGAACGACCAGAAGATGCACCGCCGCAACCGAGGCCGCCGAGGTGGCCGACCGACAGCATTCGACAGCAGGATCCACCGCCGCCGCAACACCGTCGAACGCTGCTTCAGCCAACTCAAAGGCTTCCGCGGCATCGCCACCCGCTACGAGAAAACCGCCACCTCCTACGAAGCAGCGGTCACACTCGCATCACTTCTGCTCTGGGCAAGATCAATTTGAAGACGGACCCTAGTCCGCGGACAAAAGACGCGCCCTCCCGGGCTGCGATACGGATCGCGCATCCGAACATGAGCGCGGCGTTCTGGACGCCGTCCGACATCGCGGGCGCCGACTGTCTGCGGACAGAAACATCGGGCGGGCTGATCTCATCACGCCTGTACGGATGTCCGGTCACCGTGGGCGTTCCGTGACGTCAGTGGTGACGCTCTCTCACTCCTTGGCGGGTTCCTCTCCGGGACTCCCCCTGGTACTCGTCCTCCGCCAGTAGCTTCTCGGTCACCCCTACGCCTGTGAGGCGCTCTGCCAGAGCGAGGACCGCTGCCTCGGTATCGACGCCAGGATCTCCGTCCCTTAAGCCTGATGCCGATCCCGAATTTTGGCTCTGCCCGAAGTTTCGTGATTCCCAGGTCAGGGTTCGCGTGCGGGAACGTTTCGGCAGGGCATGTCTGGCTGGTGAGGGTCCGCTCGCTGGATGATGTGCTGTTCCCGGACGTCGATGTGCGCTCGGAGGCCGTGGAGTTCACGGCGGAGGCCTTGGTCGTGGTGGCAGCCGCGTACGGTCCGCCGCCCAGATGCCCGGAGTGCCGTGCCTGGGCCGGGAGGGTCCACTCCTGCTAGAGCGACGCCGCCGAGCGACCCTTGACGGGGAAGAAGCTGCTGGTCAGGCCGCGGGTCCGGCGGCTCTTGTGTGACCGGCCCACGTGTCGGCGGCGGACGTTCGTCGAGCAGGTCAGCGGGCTGAGCAAGCGGTATCGCCGTTCGAGCCTTGGGCTGAAGGGCTGGCTGCGGCAGGTCGGGGTTGAGCTCGGCGGCCGGGCTGGCGAACGGCTGTGCCGCCGGATGCACCTCGTCGCGGCCCGGACCCGGATGTTGGAACTCCTGGGTCCTGCGACGGCGCCGGAGCGGTCGCCGCGGGCCCTCGGTGTCGACGAGTTCGCCTTCCGCAAGGGCCGCACCTATGGAACTCTCCTGGTCAAGGCCGACCGGGCCGTGGACGTCCTGCCCGACCGGACCTCGGAGACCTTCGCCGCCTGCCTGCGTGAACGCGCTGACGAAGAGACCGCAGGGATATCCGAGGCGCCCACGCTGATGCAGCTCCCGCTGCATCAGCTGCCGCGGACACAGATCCTCGAACGGACCTGCCAACGCCACGCCGACGTGCACAAACTCGTCGCGGCCGGCTGGACGATCAGTGCGATCGCCCGTCGGCTGAACCTCGACCGCAAGACCGTCCGACGGTTCCGCGACACCGACCTCGACCAGCTCCTGGCTTCCGCCCACGAACGCCGCCCGGCAGGAGTGCTGGAGCCGTTCAAGCCGTACCTGAACACATGATTCACCGAGAGCCTCGGCCAGGTCAGCGGCAGTCGCCTCTTCCTGAAGATCCGTCAACGGGGTACCAAGGAAGCCGCCAAGTCGTCCGCAAACACCTCGCCGCCCTCCGCGTCGGCACCGCCGAACCCGTCCGAGCCGACATCCCCAGCCCACGCAGGATCACCAGCTGGATCATGCGACCACAGGGCTCCCGCACCCGTCCGCTCTCCTTGCGCGAGCACATGCTGGCCGCGGGACGCCGGGGCCGGGCCGTGACCTGGCGCAAGGGCTCCAGAGCGGCGATGAGCTCGCACTTCGTGCTGCTGCGGGTCCGCCTCGCGGGGCGGCGTCCCCAACCCGCCTGCGACGGCACGATCCCGCTGGTCTGGCTGATCGCGCAGTGGCCCGAAGACCAGGGAGAATACCGATTCGTTGTGCGGCCCGGGGCGGCGTAGCCCCGGCCTGGAAGCGGGTCAGGTACCGGGCGCCCGGAAGTCGACCGTCAGCCGGGCCGCCGTGTCGATCTGCTCTGGGGTGAGCAGCCGCACCACGCTGGACTGCAGGGCGCCGCTGGCCCGGACTGTCATCGAGACGCCCGCCATCGACTCATCGTCCGGCAGCTCGATCACGCAGTACAGGTCCGTCTCACCGAAGGCGAAAGCCAGCCACTCCAGAGTGCCACCACAGGAGGCGACCACCCTACGGACCGCCTCCACCCGGCCTGTGCCCCCGTCGGAGAGCAATCCCCCAGCGCCCTGAGCGGTGTAGCTGGCCTGGACCAGGTACTTCGGCATCTCGGTCTCCCGTCTTGCGAAAGCGTCGCGGGCACGGCGCCATCCCTACGATCTGGCAGCGCGCACCGCGCCGACCACCGGGAGACGCCCAAACGGCCGCACAGACCTGCCCTCGCCGGGCCGCACCACCCGCCTCGGAGTCCACGATCATCGCATACCGTCTCGACAGGCTGCCCCGCAAGCTGTGACTGCCGGCTACCAAGTGGCGGGTTTCTCGCGTATCTCCTCCGGCCTCCTCATTCATCGGATGGCACCGCCACGTCACCCTCGTCACCGCCACCCACCTGTTCCTGACCGAACAGCGGAGCTGCCAAAAAGCCCCTGTGGAAACACCGCGGCGGCGCTCGGGAGATGCCCGACAGCGTCATGGACTCGTGGAACCTGCGGCCGATCAGGGTTTTGATCCTGGCCAGCGTCCACCGCTGGTCCGGCCAGCCGTGCGCGACCGGGCCCTTGGCAAGCTCCTCCTCAAGCACGGCGAACAGGGTCTCGCTCAGCTTCGGCCGGGACGCCGGGCCTCGGGAACGAACCCCGTCCCGGCCGGCCGCCCTCCAGGCCTGCCGCCACCGCTGGACCGACCGGACGCTGACCCCTAACTCCTTTGCAACCTCGCCGCTGCCCCGCCCCGCGGCGAACATCGCGACCGCTTCCATCCGGACCCGCTCGCGGAACGCTTGCCTCTCCGCGGTCAGACCCCCACCCTGCGGATACCTCATACACCTGGCATACCGCGACGATCACCGATCGTCAGCCCCCCACGACAACCCGACTTCAAAGTCAGTAACAAAGCACTACTACTTGCTGTCCCACGCTTCCGCGAGCGGGACCACGTGGTCGATGTCCAGTGCCCCGGCCGGGGTCATCTCCCGCTCGCCGTAGTACGACCACCACACCCCGCCCGCCAGCGTGCACCCCGGACCGACCCCCGGCGTCACCACCGCCTCAGCGATCAGCACCTCGGCACGGGTGTTGCAGCCGTCCGTGGGGTTCGCGCCCACGTTCCAGTGCTTGAAGCTCGTACGCTGATAGCCCGTCCGGTCCTCAACAGCGAGCGGGAGCGCGCCGACCGCGACCCCTATCGGCAGCAACTGCGGCACCGCGGCCGGCTGTTCGACCGCGTACACAGCGGAGGCGGGAAACGAGAAGGCGAGAGCCGCGGCGGCCAAGGTCACAGCCCGCATCATGATCATCGCGAGGCCGGTTTTACCGACCCCCACCCACCAAGCGACAGGCCTCAGGCACGAGGTTCACCCGGACGGGAAGCGACATTCACTGGCGAAACGCCACTGCACACCATCACTGGCATGGGCTGGGTGTGCACCCACCGCGCTTTGCCCGGTGAGAAGTTCAGCAACAGGAAATCCAGCAGCCGAAGCAGGCCATGACCTCCTACCAAGATCCCGCACATCTGTCCGAATAAGCGTGGCCCAGCCACGTTAACCGTGGGTAGGGTGATCACCACATGGGTGGCAGCCCCAACCGGGATGCACCCTCGCGTGTGTCAGTGGCGGCCGGGGGGCCAGTGCCGCTATGGGGGACTGATTCGTTGTACGGCTGTGCCGATCATCGGGCGCGCGCCGGTTCGGTTTGCTGCCATCTGGGCCTCAGGTCCAGCGTGCTGACTCGGGCACCTCCTCGCGCCTCGTGCTTCCCGCTTCCGCCTTCATTCGTCCATGAAGGAAGGAAATCGTGCACTTAAAACATGGCGTTTTATCCAGAAGATCACGTAGATCCCGGCTCCTGACCCCTGCCGTGACATCCGTCGTCGCGATCGCGGTCCTGGGCGGTCTGGCCATCCAGCCGGCAGTGCTCGACCGTAGTGCAGCGTTGCGTGCTGATCCGGCGGCGGACGCGTACGACTGGCTTTACGACACCTCCGCGGAGCAGTGGCGCCAGGATCAGTGCCTGATGACCGATGTGCTGCGTCTGGGCGGTCCGTCCATGGCGCAGACGGCGCAGGACGCGCTCAACCAGCCTCAGGACAAGCTCCATGCGCTGGCTGACCGTGCCCGTTGGCAGCAGACTCCGCTCGCGACCGCGTACCAGAAGGACCGGGACGCGGCGTGGAGCTCGCTGCAGGCCATCAACTCTCTGAGGGACGGCTGGAAGAAGCCTCTGGAAGGGCTGACGAATCCCCCCGGAGGCATGAACACCGCCGACTTCCACTGGCCTCCGGGTTCGCCCGGCGATGGGAAGCAGGACTTCTACACGCAGACCGGGCTGAGCAAGTGGGTAGCCGAAAGGTTCTGGACTGAGGAAGGAAGCTTCTATCAGGACCCCACCCCCAAGGCCTATGACCAGGCCAAGGGGATGGTCAAGTACCTGGGGACTCCCCTCTACGGCAAGGACCCCGACGCTCACGCTCCCGGGGGCGACTGGAACCGTGACCTCGCGGAGCACGAGGCGTTCCAGCACCTGACGGACTGGTCCCCGGAGCCTATGGGCGCGGACAACGCCCGTCTGTTCATGGCCTCGGGAGGGTTCCCCCGCAGCGCTCCGCAGCCGGGGACGGCGGAGTACCGCATCGCGGTCGAGGACCTGAAAGCCCGGTTCGCCGGCTGCGCGTGGCGTGACCCGATCGACCCGAACAGGGTGCTCGACGGCATCACCACCACCGCGGCCGGCGAGTGGCAGCAGGAGATCGTCTCCCAGCAGGCGCAGCGCAACCAGATTCTCGCTGCGAATGCCGAGGCGACCACGGCGCTCGCGGCGGGGGCGAAGGCCTTGGGCGAGATGCTGGGGCACTCGTGGGTGGCCGACCACGCGACCCGCTGGCAGGACTACTGGTCGCCTGGCGGAATCGGCGCGGTCGGTGACAAGCCCGCGGTGATCGAGCTTCATGCCGTGGGAGGCAAGTGCCTTGATGTGGAGAACAGCGGCACCAACGACGGCGCGCCGGTCCAGGTCTACTGGTGCAACGGCACCTCCGCGCAGCAGTGGCAGATGTTCGGTGATGACCACGGCCTGCATCTGAGGAACGTGGTGTCGCAAAAGTGCCTGGATGTGTCGAACAACGACCCGGCCAACGGCACGCGGATTCAAATCTGGACGTGCAACAGTTCCCCGGCGCAGACCTGGGAGTACAACCTTCGGGCCACTACCGCCATCAAGAACGTCGGCACGGGCAAGTGCCTGGACCTGCACACCTACGAGCCCGGGTACGACTCCTGGCTGTGGGACTGCAACGGCACCGGCCCTCAGCAGTTCGACATCAAGCCGTCCGGCAACGGCGCCGTTCCGGCGCAGAGTGAGTTCACCAAAGCCAAGGCGGCCGTCACCGGAGCGCAGGCGGGCGCGAAGAAGCAGCTCGACGTCCTCAAGGTCCAGGCCGCAGCGGCCAAGAAGGCGTCGACGACGACCGACACCGCCGCGCAGGCCGCGTACACGATCGCGGACGCCAACGGTGCCCCGCGGGGCCGTGGCCTGCTGGTCGGCCAGCAGAAGGCCCAGGTCACCAAGGGTGCGGTGGCCGCGCTGGACGCGATGGTGAAGGCCGGCGAGACCGCCGAGGCAGCCACGCGTGCCTCGGGCGCGGACAGCGAGACCATCGCTCAGCGTGCTCTGGCGCAGGCCGCCCAGGCCAAGGCCGAGTTCCGCAGGGAGGCGGCCCACACGGCCGAGCTTCAGGCAAAGGCCTCCGCGGACGCGGCCAAGTCTCATCGGGACAACGCGAAGAAGGACGCGGAAACGGCAAAAGCCAAGCTCGGCGACGCGGTGAAGGTAGAGAGCGACGCCAAGGTAGCGGCAGCCACCGCTCACGCGAAGCGGCTGGCCGCCGAGGCGGAAGAGGCCAACGCGAAGAAGGAGAAGGGAACCGCGGCCGCCAAGCAGGCCGAGGCGGCCCAGCACCGCAACAACGCACAGGCCGAAGCCACGAAGGCGCAGGACGCCAGGACCAAAGCCGAAGCGGCCGAGACCGCTGCGGTCGACCGGAAGAACGACGCGGTCAAGGCACGCGACAACGCCAAGGCCAAGCGGGACGACGCCTGGGACGCTGAGCAGAAGGCCGAGGCCGAGCGTGCCAAGGCCAGTGCTAAAGCCGCTTACGCGGCTTCACTCGACGCTGGCACGGAAGCGGACGCGGCACGCACATCAGCCGATCAGGCTGATCAGAACGCCAAGGATGCCGAGACGGCCGCAGGCAGGGCACGGGGTGAGGCGAACGCCGCGACAACGGCGGCCGAGGAGGCGGACGCAGCGGCCACACGCGCCGAAGCTGCCGCCAAGCGCTCCCGCGCCGACGCGGACGGCGCTCAGGCCGCGAAGCTGAAGGCGGAGGCTGCGGTGAAGACGGCGACCAGTGCCGCCGCTGACGCCATCGCCGCTTCACAGCACGCCGCATCCGAAGCACGCAGCGCCGTCGCCATGGCCGACGAGGCAGACGGCCAGGCCAAGACGGCCAAGACCCAGGCTGACCTGGCGAACCAGGAAGCCCTCAAGGCGGTGACGGCCTCGGCCAAGGCAGCCGGCTTCGCCTACTGAGGTTTTTGGCGTGGTGTCGTCAGGGTCTGAGTCCGGTGGCAGCGAGGCAGCCGTCGACGATGTGGCTGCGGTACTGGATCTTCTTGAGGCCGGTCCTGAGGGCTCGGACAAGGTCCTCGGGAGTGGCGAAGACCGTGTTGGCATGGGCGGTGCGCCTGAGGACCGACCAGATGCCTTCGACCGGGTTGAGGTCAGGAGTGTAGGCGGGCAGGTGGTAGACGGTCAGCCAGTCGGTGACCTCGATGAACTCGCGCATGCCCTTGGTGCGGTGGGTGTTGAGGTTGTCCCAGATGAGGATGATCGGGGCGCCGAGACGGCCGTGGGCGTAGACCAGCAGCCAGCGGAAGTCCCTCCAGTCGTAGCTGCGACGCTCGCCCTTGGCAGGTCGCCGGTTGTGGACATGCAGTTTGTAGAACAGCCGTGAGCGTTCGCCGGGTTTGTAGCAGCACAGTCCGGCGAGGGTGACGCGGCAGCGGGTCCAGCCACGCATCCGGATCGTGGGGGTGAGGGCGCGACGGGCCCATGTTCCGCGGGACGGCGGCGTCATCGAGAAACCTGCCTCGTCCTCGAAGACGATCCAGGCCCCGAGCGCCGCCGCAGTCATTCCACGTGCGGCCACGTGTCCTTCATCCAGCTGGCCACCGCGGCATCGTCCCGTTCCAGGGCGCGCCTGGCCGGAGCCTGCCGGCTCCAGCCTCCACGCCGCATGGTCTGGTAGACCGCCGCGATGCTCAGGCTCACACGCAACCGGCGGCGGATGACCGCCTGGATCCTGGCCAGCGTCCAGGTCTGGTCCGGCCAGCCATGAGCGATGGGGCCTTTGTCGAGCTCTGCTTCCAGCACTGCGAACTGTTCGGGGCCGATCTTCGGCCGGCACATCGGCCCGCTCGAACGCAGTGCCCGGCGGCCGCCCTCACGCCAGGTCCGGCGCCAGCGCTGCACCGACCGCTCACTGACCCGTAATCGCTTCGCGATCACCTGATTCGTCAGCCCTTCAGCGAACCAGCCTGCCGCCTCCAGGCGAAGAGCCTCCCGGAAAGCCTGACGCTCCGACGTCAGACCCCCACCCTGCGGATACCTCATACAACCGGCATACCGCGACGATCAGCAGCCGTCAGCCCCCGACACAACGTAAAAATCCTCAGTATGTCACCGCGCAGGCCGCGGCCGATGCCGGCAGGTCTGCGTTTCGTGTATCCGATCCGGCGAACGACGCCATCCAGCTCGGCTCCCCGTACGTCACCACGGACTCGACCGCGACGCTGATCGTGCTCACCGGGCAGGCATCGAAGACAATCGCCGAACAGCAGAAGGCCATAGCCGAAGCACACGCCAAGAACGCCCAAGAAGAAGCCGCCAACGCCAAGGCCCTTGCCAACCAGGCGCAGGAAGACACCAAGGCCGCCTACCAGCACTCCGCCAACGCGGCCGGTTACGCCGCTGACGCCCGCGGCTACGCCAAGGAAGCCCTTGGCTACTCAGCCGAGGCCGCCACGTCCGCGTCCCTGGCCGCGGCCTCCCTGGCCCGCACCACCGAATTCGGCCGCCAGGCGGCAGAAGACGCCGTCGCAGCAGACCAGGCCGCAGACCGCTCCGAAGGCCACGCCAAGGACGCACGCAACTCCGCCGACCAGGCAGCCCTCGACGCCACCGCCGCCCGCAACGCGGCAGCCCAGGCCGAACAGGACGCCAAGGCAGCCCGCACAGCGGCCGACCGCGCCGCCACCGAAGCCGAACAAGCGGCGAAGGACGCCGACAAGTACGCCAAGGAAGCCCAGGAATCAGCCGACCGCGCCGAGAAGGCCGCCAAGGCGAAACAGATCAACGCCGGAACCGTCGTCGACCAGACCGGTGGCTCCATCGGCAACATGTTCTACGCCGTCAAGCGCATCGACAAAATCGGGGATCCCCAGACGGTAAAGAAGACCGAAGCCTGCGACAGCTGGATCGACAAGCTCGCCTACAGGGGCGGCTGCACCGTCACGGTGAAGATCCGGTACAAGGCACTCCTCGACCTGTACCTGTGTAACGCGCCGGTCCTGGACCCATCGAAGTCCACGTGTCCCGCTGATGCGACGACCTATCTGGGCGAGTACCCGACTGCGGAACTGTCCCAAGAGCTCACGCACACCATCACGATGGCCGAATACCAGGCGACCGTAGACCCAGTCGACATCCTCTTCGGCAGCTGGATCAAGTGCGTTCAGAAAATCGTACCCGGCGGCGAGAACGGAAGCTGGGGCGGATGCGCCTGGGCCGGGGTGGACGTCGCCCTCCTGTTCTCAGGGAAAATCCTCAGGCCGATCGCTGACGCCGTCAGGGCGGCTGATGCCGCCGCCAGGACCGGTATCGGCGTCGCGGACGCCTACAAGGCCCTGCGCACGCTTGGCCTGACCGAGACCGCTATCGAGGGTATCGGCGCCAGAGCACTGAGCGGATTCGCCGAAATGTGCGCCACCAAACCAAGGGCCAAGGCTCTTCGTGTGGCAGCCGCGCAGAGCGACGACCCTTGCATGGGGATGATTCCCTATTACAGCACGGAACTCAGCCGAATGGCATACACGGCCAGAAAAGCAGCAGGATTCACCTCTGGTCGCAATGTTGCGGTAGCGAGGGTTCCCGGCTGGAATAATCCGAAGACTGGCGATCTCGTGGTCGGCTTCAGTAAGGGGGATGGATATCACTCAGAGGATCACATCCTCGACCAGCTGAAGGCGAAGAACTTCAAGCCGTCTCAGATCACCGAGCTTTACAGCGAGCGGAGCCCCTGCCCCGAGTGCAAGCCCAAGTTGGCGGCAGTACTAGAGCCCGGGACCCCGATCTCGTGGTCCGTTCCCGACGGCGCAGGTTCAAGCGACTGGCTCTACGCCATGATCCAGGCGCTAGAGAGGCCGTCCTTCAAACAGTCCGCTGAACAATAAGATCAAGGTGCGGTGGGCCTCCCCGCCCTGCCGCCCACCACACCTGGCCACAAGAAGGAGGAAAAACTCTTGACAGAGTATGGGTTCATCCGCGCTTCCGATGAGGTTCTATCCATCCGAAATAAACTAGCGGACCAGGTCATCCAGGCTCTCCAGCGCGCCGGCTTGCCTGCTTTTCGTGAAGGAGAATCCGGATTCCAGGACCAGGCTGGCGCGGTGGTCCATGTCGAACCAGACGCCGAGACAATGTCAGCATCGGTATCCGTGGGATGGCGATGCAGCGCCGGTCAACTGCAGTCCGCTTTGGAGGATCTCACCTCGGGACTAACTGACACTCCTGCCACCCGCTACCCTGGCACGGTTGGTCTACATATGCAGATACCACTCATCAAGATTCTACTGTCGGCGGGGATCATCGCCACCCCCAATAATGACAATATGAATCCGAGTCATGTCCTAATTTTCGGGCGGACATCTGACCTACCACCCGAACTGAGGCCCACGTTCCTTCCACCAGGAACGTAACCAAAGGAAATTCCTGAACGGTCCGTCGGTTTCCATCGACGGGCCGTTCCGGCCGTCCCAGCCGAACCTCGGCATCTTCGCATCGGGAAGCCGCCATCACATGCGACAGCACACAGTCAGCGGCCCCCGCCGGCAGCACCATCGCAGGCTGCTCGGCCGCGTAGACAGCAGTGGCGGGAAGCGACAGAGTCAGAGCCGCGGCGGCCGTGGTCACGGCCCACATCATGAGGCCGCTCGTACCGTCCACTCACGCAACGGCCCTCTGGCGAACACAACCCTCACCCGGCTTGAGCCACCGGGCTCAGAACTTGGCAGCACCGGCTGGCGGCGAAAGCACAGCGACGGCGATAGACGGCTCTCGTACTGTCATGCGGCACTAACCTTGGTGCGCCGCAGTGATGTTCCAGGGGGGAGCTACCCACCGTGCAACCTTTGCAAGAGCAGGAACCCGAGCAGGTCGCCGACTACCGGCCTCTTGGCCGCCTAGGGTCTGCCGTCAAAGTGATCTTGCGTTGTGGATCATGGTCGGGTGATACGTCGCCATGAACTGTCGGACGCTGAGTGGGAACTCGTGCAGCCGTTGCTGCCGCAGCCTGCGCTGGGGCGGCCGCGGCTGGACGACCGGACGGTCCTGAACGGGATCGTGTGGAAGTTCCGGACCGGGGTCGCCTGGCGGGACGTGCCCGACCGGTACGGGTCGTGGGCCAGCCTCCACACCCGTTTCCGCCGGTGGGCGGCGGACGGAACATTCGAGCGGATGCTCCAGGCCGCGCAGGCGCAAGCGGACGCGGCAGGCGACATCGAGTGGCTGGTGTCGGTGGACTCCACCGTTGTCCGTGCCCACCAGCACGCGTCCGGGGCCCGAAAAGGTGCCTCTATGGCCTTCGTCAAGCCGTAGCCGGTATGGGCGGCTGGGTAGAAGGTGCCGTCTCGGAGCATGGCGAAGAGGACGTCGATGCGGCGTCGGGCGAGCGCGATGAGGGCTGCGATGTGGTGTTTTCCCTCGCGGCGTTTGCGGTCGTAGTAGGCGCGTGACTCCGGTTGGGACAAGGAGGCGAACGCGGCGAGGTAGAAGGCTCGTTTGAGCTGTTTGTTGCCTCGCCGGGAAGGATGTTCGCCGCGGATGGAGGAGCCGGAACTGCGGGTCACGGGTGCCAGGCCGGCGTAGGCGGCGAGGTGGCCGGCGGTGGCGAAACCGCTGCCGTCACCGACGTCGATCAGGATGCGGGCCGCGGTCCTGATCCCGATGCCGGGCATCGAGATCAGGACCTGGGAAAGAGGGTGGGCCTCCAGGAGTTCCTCGATCCGGGTGGCGAGGAGTTTTCGCTGGTCAAGGACGGATTGGAGGGAGCTGGCGAGGCTGGGGACGATCAGCGCGGCGGCGTCAGTGCCCGGGACGACGACGGTCTGTTCGTCGAGTGCGGTGAAGATGTCCTCGACCAGCTGCTCGGCCATCCGCGGTGCCTTGGGACGTATCAGGGTCGCCAGGCGGCGGCGTCCGGCCTTGCGGATCCGGGCCGGGGAGCCGAACTGGTCCAGCAGTTTCAGCACGGCCGGGTGCTGGATCCGCGGGCCCAGGACACGTTCCAGAGAGGGGTGGATCTGGGTGATCAGGCCGCGGAGCCGGTTGGCGATCCGGGTGGACTCGCCCGCGAGATCGTCGTCAAACCCGGCGATCATCGCGAGCTCGGCAACCGTTTCGTTCGCGAGATCGATCGTCCGCCGGGTGTGGGGCATCGCTCTGGCGGCGTCCGCGATGATGAACGCGTCGCGGGCGTCGGTTTTCGCCTCGCCAGGATAGAGATCGGCGATCCGCCGCATCGTCAGTCCCGGCAGATAGGCGACCTGGCAGCCTGTGTCCCGGGCGACCGCCAGCGGCAGGGCTCCGATGGAAGCAGGCTGGTCGACGACCACCAGCACCGTTCCGTGCTTGGCCTGGAGCTTGTCGAACAGCTCCCGCAGTTTCGGTTCGCTGTTGGGCAGAGGCTTGTCGAACACCCTCTTCCCCGCCCGGTTCAGGGCAGTGGCATGGTGATCGCCCTTGCCGACGTCCAGGCCCAGATAGACGTCGATGCCACTCTCGTGCGACATGCCCTTCGCTCCCGTGCTCGCCCGTTCCCCGGCCTCACCTGCGGCATCAGCGTGCCGGCATCCACGTTACGAAGAGATGCCTCGCCCATCCACGGGTCCGGCGCTCGTGCCTCTAATCAGCGGTCTGCCAATGCCTCCGACACCGGCGACACCACCTTTTCGATCATCATCGACTGGGGGCTCAAGTCATACCGGGGCCGAAGGCCGGGAGCCTCATTACGAGGCCACGAAGACGGTAACGGGGCTCCGCAGCCCGGCCCTCGGCCGGTCCCGCAGCGGGCTGACCAGCAAGATTCACCTGGCCCGCGACGGGACGGGCCGACCCCTCGCGTTCGTCCTGACCAGCGGGAACATCAACGACTGTACCCAGTTCACCGCCGTGATGGACGCGATACGGGTGCCCCGGATCGGGCCGGGCAGACCGCGCATCAGGCCCGACCACGTCATAGGCGACAAGGGCTACAGCTCGAAGGCCATCCGTTCTTGGCTGCGACGCCGCGGCATCACGCACACGATCCCGGAACGATCCGACCAGGTCCGCAACCGAACCCAGCGAGGCAGCCGGGGCGGCCGACCGCTGGCTTTCAACAAGCAGGTCTACAAGCACCGCAACGTCGTGGAACGGTGCTTCAACCGCCTCAAGCAATGGCGCGGCATCGCGACCAGGTACGACAAGACCGCCCAGTCCTACCAAGCAGCTGTCACCCTCGCGTCGCTCCTGATGTGGGCGTGACACTTTGACGACAACTCCTAGCCCGCACAGGTGATACGAAACAGGCAGTCAGAGGGCGTTTAGCTCATAATTTTGGTTTTTTGAGCCGGTATGGGCTTGCGGCCGGTCGGGGCTGCTGGGGTTGGTGTGGTTCATGGTGCGAAAGTGGCTGCCAGACGGGCTTCTTGGGCTGCCTCCTCCTGTTTCATCCCAAGCCGCCGGGTTTCACGCCGTGTGCTTCGGGCGCCGGTCCGCGCGCCTGGGCCACCTGGGTAGCCCGGAATCATGCCTGAACGCCGCCGATACCCAAGCGATCTGTCCGATGCCCGGTGGGAGCTGGTCGAGCCGGTCCTGACCGCCTGGCGGTCCGAGCGCCGCGGCCGAGGCCTGGACATCGGCCGGCCTCCGGACCACGATCTGCGGAGCCTGCTGGACGCAGTCCTCTACGTGAACCGGACGGGCATCCCGTGGCGCTACCTTCCGCACGACTACCCGCACTGGAACACCATCTACGCCTACTTCGCCCGCTGGCAGGAAGAGGGTGTCTTCGACCAGCTCAATACCCTCCTGCGACGTCAAGTCCGCAGGCAGGAGGGCCGCGAGGAGGAACCGACCGCCTGCGTCATCGACTCCCAGAGCATCAAAACCTCTACCAACGTGCCCGCCTGCGAGCAGGGCATCGACGCCGGAAAGAAGATTGTCGGACGCAAGCGGAGCATCGTCATCGACACCGTCGGACTCCTCCTGGCCGTCGTGGTCACCGCCGCGAGCGTGCAGGACTCAATCGCCGGGCAGACCCTCATCGAACGGGTCGCATCCGAGCATCCCACCATCCGCAAGACCTGGGTCGACGGCGGCTACCGCCAGCACCTCGTCGAGTACGCCGCCACCCTCGGCATCGACATGCACATCGTCCGCCGCGACCCCACCACCAGGGGATTTACCGTCCTGCCCCGCCGTTGGACCGTCGAAAGAACCCTCGGCTGGCTTATGAACCACCGCCGTCTCACGCGCGACTACGAAGCCTGCCCCCACCGCTCCGAAGCCATGATCCACCTCGCGATGATCAACCTCATGACCCGCAGACTCACCGTCGAATCCACCCCCACATGGCGCGGCGCATGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP024985|143990:192902|159600_160329_-|WP_158740950.1|DBSCAN-SWA
MTVDRGSFRYCEVLGHDSRHLFFVFPASIRGDDCSEPETAAASLVGCRRVVGTVRVLVPLGLAGGLGGLGLGGAGLSGSVGALLDLGGLLRVGEAGPRDGFLAQSAGLLHGLGLLAALGFGLLGQVRAPLGVGLLQALPERGQGGTVVGEGLDDGGRVDGSSTIAASSMTRTPTPARPRPPAADPTQVVRGGESVLDLGIDALVAAAVLGEPVLDLLRRADRRRVPHPGPPPFAVVRPPSEP
>NZ_CP024985|143990:192902|164258_164621_+|WP_030240054.1|DBSCAN-SWA
MPVGPRALHWPDLVLVLPGGTLGAVEVELTAKTPSAIRRILRAYGQARRRVLYLGTEPVVRQLQGRPGPDGRWADGVAQDVGLLPPGGPDPGTGGLLRVQPFTAGDPAVDRQAARYAKRR
>NZ_CP024985|143990:192902|154624_156022_+|WP_158740948.1|DBSCAN-SWA
MAILTADQALIVQLTDALSAAAEATDTVPPPPVYVASGGGVTVQGTGNRLRGDFAGRDQIIHNIRHGDARTLVVLAVVAIVLAFAVYGGVQAVGGLNSGGASGQPGIGASPRGATDRQGGTGTSPSAPKNTVLWTVPKRPWPFSPPVVSGGRVYYLVSNEPAGIELMVVDASTGAVVPEFTARLDPNSLPGPLTVADGRFYLVDDNGVLYAGDDKRILWRYSTGAKILSPPKPTVADGTVYFGGSGVSHELHAVDATAGTERWTFTAKSRISTAPAVSGGVVYAGTDDGDLYALDAVTGKPLWTFPGGEGFFHGAPVVAEDTVYIAGDKGTMFAVDKTRGTKVWTFHAEGDAEGLSRYPLIFGNTVYFGGDNKVFYALAADTGTKRWSVTTGGSLARSPVLADGIVYFGMWFGKLYAFDAVTGKEVWSHTTEGELPQDPAIGEGTIIIATRNENKTEGHLYALRR
>NZ_CP024985|143990:192902|175121_176687_+|WP_158741059.1|transposase|DBSCAN-SWA
MEVDQLVMTDAEVRVAVRSGAVAAACSGCGRRSSRVHCYYQRTLADRPVAGRRVRIELRVRRLVCGNEHCPRRTFAEQIPALTHRHARRTDALTAQLTDVALFLGGRPGTRLVQRMTIDTCKDTVLRLIRALPLPSSGPVPHLGVDEFAVRRGRTYATILIDMATHRPIDVLADRAAATFASWLRNHPEVRIICRDRAGSYRDGAQTGAPQARQVADAWHLLNNLAQAVERVIGRHRSDLRQPLTSHDDRSDEGPASEGRDRAELDIHGRPRPLVARTRERHQQIHERIERGDSLRAIARDLQLSRGTVNRFARTAEVDELLLAAIHRPTLIDDYRLYLHHRWMEGCTSASALAREIQRLGYRGDVNTVRRHLKPYRNGAIPTTAPLPHLTVRRVTDWIMRRPEHLTDAERKGLDELCERNHVLATTVEYARRLALMVRDRHSEHLALDVWIADVRLDGQQELRTLANGMRRDRAAIQAVLTTTYTSGAVEGNVTRIKLLKRQMYGRANFDLLRRRILLSP
>NZ_CP024985|143990:192902|160997_161444_-|WP_106979792.1|DBSCAN-SWA
MTKTTSQKQRHRTAPAVGVASVAPKGESSRFVITSQACSILDAFLQDPERPRYGLELMKITGLSSGTTYPVIYRFERAGWLTAAPEPIDPQKAGRSRRRSFKITPEGIRGAQIAMTELRHEAALRGADQRRKASAIPPIPGYTAGATG
>NZ_CP024985|143990:192902|168240_168918_-|WP_030240062.1|DBSCAN-SWA
MSVRVLLVDDQPLMLVGLGILIGDTADLEVVGEAGDGVEAVRLVRELRPDVVVMDIRMPGMDGIEATRQATAEPDPPKVLVLTTFDDDEYVYGALRAGASGFLLKSMALDAILDAIRVVAAGDALLAPSVTRRLIADFAGTSATPAPATEPAADSSLVAGITDREREVLALVGQGLSNGEIAERLVISAATAKTHVARLFAKLEARDRVHLAIIAYENGLTPGRR
>NZ_CP024985|143990:192902|163433_163634_+|WP_159038048.1|DBSCAN-SWA
MAPAQAVTTSTPKAASASVMGEMVFYDDFWTQSECVAVGKQGQSARMWKIYSCQPSLWDWDLYVGY
>NZ_CP024985|143990:192902|170253_171459_+|WP_030240065.1|DBSCAN-SWA
MKRNRRISAVAALALAALVTGTGTGFAATTTPSATPVATHAFDTAPATATAPTRSFQGTLPAPTGPYAAGKEVIHLTDANRPDPWVPSSGPRQLTVTMIYPAVPGTGTPAPYMTLGEAAGILQRQKTPASSGVTPQTLSSVTTHAFDGARPQRGKYPLVVLSAAHENPRMTLTALATDLASHGYVVALVGHTNEDSGETLANGQTPPCAICDNPALNLDSVVASRATDVSFVIDQLTHGNTAWRLAHLIDKHQIGMAGHSLGGASAAATMIADPRVRAGVNMDGTFHPTPMPGQINRPFLMLGTAENHSAGGHNTTWEQAWAALGGYKEWLTVTDADHFNFSDLDLLKKQAGFPTQGLSPERGLVITREYVTAFFDQTLKGIHSPLLDGPSPNNPEVLFQH
>NZ_CP024985|143990:192902|165354_166023_-|WP_158740956.1|DBSCAN-SWA
MDDAYVQPGDESKSVAFRGAMTPSAETISQLSERQNFKSWVQETGAVGLADIQSLVITLGGYDEKNEASVTGAELVDKHCEPALRGTLFESPGGGGGSPIPNVRFDLDKPVVSPKAFAKKEYKLKKGEQQTFVIETTTKNQACEFRVLFHVRVGTKTTTVTADDAGRPFKVTSRLPYEQYQVLYVGGIYCSGPLPYYRQDPKLFAVGRQCSKAGVTEGQTTP
>NZ_CP024985|143990:192902|191195_191798_+|WP_159038049.1|transposase|DBSCAN-SWA
MPPTPATPPFRSSSTGGSSHTGAEGREPHYEATKTVTGLRSPALGRSRSGLTSKIHLARDGTGRPLAFVLTSGNINDCTQFTAVMDAIRVPRIGPGRPRIRPDHVIGDKGYSSKAIRSWLRRRGITHTIPERSDQVRNRTQRGSRGGRPLAFNKQVYKHRNVVERCFNRLKQWRGIATRYDKTAQSYQAAVTLASLLMWA
>NZ_CP024985|143990:192902|182735_185528_+|WP_030242208.1|DBSCAN-SWA
MHLKHGVLSRRSRRSRLLTPAVTSVVAIAVLGGLAIQPAVLDRSAALRADPAADAYDWLYDTSAEQWRQDQCLMTDVLRLGGPSMAQTAQDALNQPQDKLHALADRARWQQTPLATAYQKDRDAAWSSLQAINSLRDGWKKPLEGLTNPPGGMNTADFHWPPGSPGDGKQDFYTQTGLSKWVAERFWTEEGSFYQDPTPKAYDQAKGMVKYLGTPLYGKDPDAHAPGGDWNRDLAEHEAFQHLTDWSPEPMGADNARLFMASGGFPRSAPQPGTAEYRIAVEDLKARFAGCAWRDPIDPNRVLDGITTTAAGEWQQEIVSQQAQRNQILAANAEATTALAAGAKALGEMLGHSWVADHATRWQDYWSPGGIGAVGDKPAVIELHAVGGKCLDVENSGTNDGAPVQVYWCNGTSAQQWQMFGDDHGLHLRNVVSQKCLDVSNNDPANGTRIQIWTCNSSPAQTWEYNLRATTAIKNVGTGKCLDLHTYEPGYDSWLWDCNGTGPQQFDIKPSGNGAVPAQSEFTKAKAAVTGAQAGAKKQLDVLKVQAAAAKKASTTTDTAAQAAYTIADANGAPRGRGLLVGQQKAQVTKGAVAALDAMVKAGETAEAATRASGADSETIAQRALAQAAQAKAEFRREAAHTAELQAKASADAAKSHRDNAKKDAETAKAKLGDAVKVESDAKVAAATAHAKRLAAEAEEANAKKEKGTAAAKQAEAAQHRNNAQAEATKAQDARTKAEAAETAAVDRKNDAVKARDNAKAKRDDAWDAEQKAEAERAKASAKAAYAASLDAGTEADAARTSADQADQNAKDAETAAGRARGEANAATTAAEEADAAATRAEAAAKRSRADADGAQAAKLKAEAAVKTATSAAADAIAASQHAASEARSAVAMADEADGQAKTAKTQADLANQEALKAVTASAKAAGFAY
>NZ_CP024985|143990:192902|156216_156543_-|WP_030240035.1|DBSCAN-SWA
MTTTPPADPRIEAVAARLKEAAQKRAEAYAPPPAWQPIWKRPRKPKSIKAKKEELAKQRKRLKAAGVRRFYGAQARRPRPRQNRIGSAAGRRDARALSRMRHSNAWLW
>NZ_CP024985|143990:192902|167547_168156_-|WP_030240059.1|DBSCAN-SWA
MLTVVQVLGVSNEDEMVACFLSGELSSQRFGQNLRSHLAVAGQAEQLLTHPDLSDAGANFARRALLAATRGYGENRDLFENFPAHVTWTRALLSTDEAADVRYLDNPYWVELSGGSRRPADAAARIKAGLRAFDVPNEPFVDAAHAFIRGERFPPLILVGERQDNLVCLEGHLRLTAYALAGFPADIECLIGTAPAMGRWAR
>NZ_CP024985|143990:192902|189488_189872_+|WP_100661220.1|transposase|DBSCAN-SWA
MDHGRVIRRHELSDAEWELVQPLLPQPALGRPRLDDRTVLNGIVWKFRTGVAWRDVPDRYGSWASLHTRFRRWAADGTFERMLQAAQAQADAAGDIEWLVSVDSTVVRAHQHASGARKGASMAFVKP
>NZ_CP024985|143990:192902|152627_153110_-|WP_037688841.1|DBSCAN-SWA
MTRNTLQEDMDGLQRHDPDDMWHALTRLHASHPEPPDRILPHLTPDVLLSLTRSDLLWRVRVELAGGETMADLYNLVANLIPAALETDERRALPGETLEIVVGTRDELTLHPAHVHGLTQLLRDAVTTIDAHSTPGRGLCSHCHGTGRGHPLWAPAAGQA
>NZ_CP024985|143990:192902|181840_182218_-|WP_158741081.1|DBSCAN-SWA
MTLAAAALAFSFPASAVYAVEQPAAVPQLLPIGVAVGALPLAVEDRTGYQRTSFKHWNVGANPTDGCNTRAEVLIAEAVVTPGVGPGCTLAGGVWWSYYGEREMTPAGALDIDHVVPLAEAWDSK
>NZ_CP024985|143990:192902|186796_188449_+|WP_167456779.1|DBSCAN-SWA
MLTGQASKTIAEQQKAIAEAHAKNAQEEAANAKALANQAQEDTKAAYQHSANAAGYAADARGYAKEALGYSAEAATSASLAAASLARTTEFGRQAAEDAVAADQAADRSEGHAKDARNSADQAALDATAARNAAAQAEQDAKAARTAADRAATEAEQAAKDADKYAKEAQESADRAEKAAKAKQINAGTVVDQTGGSIGNMFYAVKRIDKIGDPQTVKKTEACDSWIDKLAYRGGCTVTVKIRYKALLDLYLCNAPVLDPSKSTCPADATTYLGEYPTAELSQELTHTITMAEYQATVDPVDILFGSWIKCVQKIVPGGENGSWGGCAWAGVDVALLFSGKILRPIADAVRAADAAARTGIGVADAYKALRTLGLTETAIEGIGARALSGFAEMCATKPRAKALRVAAAQSDDPCMGMIPYYSTELSRMAYTARKAAGFTSGRNVAVARVPGWNNPKTGDLVVGFSKGDGYHSEDHILDQLKAKNFKPSQITELYSERSPCPECKPKLAAVLEPGTPISWSVPDGAGSSDWLYAMIQALERPSFKQSAEQ
>NZ_CP024985|143990:192902|148580_150068_+|WP_051841446.1|DBSCAN-SWA
MIISRVPAPVLSAGLFIGAMAAVGTGVATLWWGIPAAVCAFLAGWQPGRNRSTGAALVGVLAAAVVAVLLVPAWLGWASQFVGLLLVAAMLPWFAGRFLRQYRELVRAGWERAARLEREQHLVAEQARLRERTRIAQDMHDLLGHDLSLIALSAGALKLAPGLSEDHRATARDIRARAGAAVDRLGQVIGVLREPSDPAPGSEPGAGITELKGLVDRAAAAGLDVRLRVEGEAAAGDALPVIERAVQRVVQEALTNVAKHAPGHQATVVVRHAEGRTEVSVTNEPVPSASAAHHGRAARTAPEPRASAPGDGHHFGLIGLDERVRLAGGTFTSGPEGDGFAVRATLPHRPGSVPPPRGAEPGDPGAVLPPEHRSARRRLGRTAAAAVLVPLCTSALLIGGVRVWDTMTARQAVLAPQDYARLHVGQPRADMARYLPERQTTRRPAAPTPAPQDAACEFYVQTADPFDDRSGDIYRLCFRAGRLVSTDNYTGKDVR
>NZ_CP024985|143990:192902|152348_152561_+|WP_030240024.1|DBSCAN-SWA
MKPNEQHIAEPGLVVLNITGGDEDTVRAVMAALEERWATSGVGPVRRDPGEPGVRARIYADVLRPGREAP
>NZ_CP024985|143990:192902|172363_173299_+|WP_078950784.1|DBSCAN-SWA
MPTHHARPLPRTGIDPPSQARAIRHCLAGVHAMAGLADDWTERRQTCIDVLCAYLRMPYPGILAEGTPADGDSNGQANREVRLTVIRTIRDHLLTATPQETSWSGYDLDFTGAVFDGGDFSNATFSGDKVRFTGATFSSGLVSFYGATFSGGSLGFYGSTFSGSEVLFRGATFSGGSVNFRGATFSGGSVNFREATFSSDVVNFDRAKFSGSEVGFYGATFSSGKVSFYGAKFSSGTVNFDRAKFSSGAVNFDRAKFSGATVTFRTAQFDGGVVDLRDAATWSRPPSLDDGLLTALPAGLLLPGQLPRPNP
>NZ_CP024985|143990:192902|153599_154013_+|WP_100661221.1|DBSCAN-SWA
MEAVVEEVFGLACQDDVQPGEGGGAGVAVALPERSTGDEGHPQTVDLLLDRGVDINAVMKHKTALDWAVGFGQEEMVHRLLGRSAIPSAATLAAAREYLVRHPECRRKTERIAVALLAVDVVPGTDQEPGTGAGNLA
>NZ_CP024985|143990:192902|180725_181046_-|WP_030242206.1|DBSCAN-SWA
MPKYLVQASYTAQGAGGLLSDGGTGRVEAVRRVVASCGGTLEWLAFAFGETDLYCVIELPDDESMAGVSMTVRASGALQSSVVRLLTPEQIDTAARLTVDFRAPGT
>NZ_CP024985|143990:192902|186128_186611_-|WP_100660733.1|DBSCAN-SWA
MRYPQGGGLTSERQAFREALRLEAAGWFAEGLTNQVIAKRLRVSERSVQRWRRTWREGGRRALRSSGPMCRPKIGPEQFAVLEAELDKGPIAHGWPDQTWTLARIQAVIRRRLRVSLSIAAVYQTMRRGGWSRQAPARRALERDDAAVASWMKDTWPHVE
>NZ_CP024985|143990:192902|146405_146684_+|WP_158740946.1|DBSCAN-SWA
MVTDDDHCYIRVLGPDSPDPGLEWDPVSFETVDTRIPPGWTLAIAGGRTRLADARWQRPGFWTDYYRGDPQARADYDHVKSELLAAAPPREN
>NZ_CP024985|143990:192902|179577_180273_+|WP_158741079.1|DBSCAN-SWA
MTGKKLLVRPRVRRLLCDRPTCRRRTFVEQVSGLSKRYRRSSLGLKGWLRQVGVELGGRAGERLCRRMHLVAARTRMLELLGPATAPERSPRALGVDEFAFRKGRTYGTLLVKADRAVDVLPDRTSETFAACLRERADEETAGISEAPTLMQLPLHQLPRTQILERTCQRHADVHKLVAAGWTISAIARRLNLDRKTVRRFRDTDLDQLLASAHERRPAGVLEPFKPYLNT
>NZ_CP024985|143990:192902|160325_160979_-|WP_030240041.1|DBSCAN-SWA
MVPFHAEVAPTSASMAHTQMTMVEKMSDTLLGVDRPAWVAAVVVGVALLVAGIVFKWIRAKTYRKAGRLPVLILYGARLFMQREDWERSYTEDWCPDVEKIMEGPTPTWASRFRRYAEAVTFALSLAVKGSRLADQIFTERPPVTVRAMKAIAALIRFDGFKVAVILLLTAGVGAGVTAMIDMPMSVLTRIAMGAGISLSLGCICLLSLRLRWRQRR
>NZ_CP024985|143990:192902|161586_162051_+|WP_100660732.1|transposase|DBSCAN-SWA
MTSRVWASGIVTDTLGLLLAVLVTAASVQDSVAGTSLLDQVAAEHPRIRKVWVDGGYRQHLVEHAARLGIDMEITARKPGTRGFSPIPKRWAVERTYGWLMLHRRLARDYETLPTRSEAVIHIAMTDLMARRLTGENTISWRDPKKTTEHPIPG
>NZ_CP024985|143990:192902|185547_186132_-|WP_078950792.1|DBSCAN-SWA
MTAAALGAWIVFEDEAGFSMTPPSRGTWARRALTPTIRMRGWTRCRVTLAGLCCYKPGERSRLFYKLHVHNRRPAKGERRSYDWRDFRWLLVYAHGRLGAPIILIWDNLNTHRTKGMREFIEVTDWLTVYHLPAYTPDLNPVEGIWSVLRRTAHANTVFATPEDLVRALRTGLKKIQYRSHIVDGCLAATGLRP
>NZ_CP024985|143990:192902|159090_159402_-|WP_030240039.1|DBSCAN-SWA
MIGQDVDDVAARDHIGGGEVFEGLPLGGVAGGDSAADPDPQENLCFEGLDRAADGCVRLRPAGDGAGLVGPEDVEPRGGGVPVGRSRARPTSTTSLTVANMAS
>NZ_CP024985|143990:192902|150439_151438_-|WP_106979791.1|DBSCAN-SWA
MDSIKRYGWGRRLLMAVASAGVGAAAVVRLAPGGVLGTNEPAHGTAGFSVRAYRALTGSVADGPSWAETVLEGASEGTLLFLGLLLAWVGWRALRRRDAAVLAGVAVAAAGTVVAYAVSEALKLLVDEERPCRALPGVAALAQCPAPGDWSFPSNHATLAVALAVGVVLIRPRLAALALPVAGAAALLRVLVGVHYPHDVLAGAALGATAVMTVWLLVRPIALRAVSAVHLRQPVGRHRDHAGLVRDHRRRGPVVDAEAGEDRADVGLHRPLRQAQAARDLPVGEPAAEEAEHLPLPPGQGLDAGAGRGTAVGLGSHTARGEMRDDAGRDLR
>NZ_CP024985|143990:192902|192062_192902_+|WP_100660736.1|transposase|DBSCAN-SWA
MPERRRYPSDLSDARWELVEPVLTAWRSERRGRGLDIGRPPDHDLRSLLDAVLYVNRTGIPWRYLPHDYPHWNTIYAYFARWQEEGVFDQLNTLLRRQVRRQEGREEEPTACVIDSQSIKTSTNVPACEQGIDAGKKIVGRKRSIVIDTVGLLLAVVVTAASVQDSIAGQTLIERVASEHPTIRKTWVDGGYRQHLVEYAATLGIDMHIVRRDPTTRGFTVLPRRWTVERTLGWLMNHRRLTRDYEACPHRSEAMIHLAMINLMTRRLTVESTPTWRGA
>NZ_CP024985|143990:192902|162356_163091_-|WP_158740952.1|DBSCAN-SWA
MTLILGWGDPLQLFHEARSAPESRATWHAMLAGLRTSSVKGGYPGVAEAVEVEFTPLGAYMCLGLPLHHLANDHVHPDEVLGTGWSARLTEQLIATPDWEGRWAVIENALARRMVDAPPPSPVVAEAWSQLRACHGQLSAKDLAATTGRGSRRLQVLFREQIGLPPQSVSRILRFQRALTLPPEACRSLADRATLCGYYDQAHMNRDFRDLVGLTPAQLCVLAESAVSRGNAPIDGRLANVFCH
>NZ_CP024985|143990:192902|176803_177898_-|WP_030242091.1|DBSCAN-SWA
MFVFVCVRCGSKLTAPLSQVALPAHARQKYGNGLQLPVLMESGTFAVELEPWGPPWRRWEEIDPDEAAARGIYAPVHALSDGVSGAVVIAPGDTRGAVLIPEKRGGACCGFDGGDGPNMACAACSLPVASRIDDCSLWQAVWLAPNAVRRLPVEGADPGPLSWADLLAEGDGVPPSEPIPPWGEPFRASDRWHWSPQWVAAAGQALAHLLVASDGRAVAVPDGLTAKMFQRALDTLLPAGGPRRRAVLAGPGQPAHDGADILLVPSHPQTGKAWTPATPARLVPLPFGVWLRLVFPEPQLPVPSSGPIPDGVLRDDPPTPNVHDMFRIDWGVFQRTLARLPAVRAPWLRQIHDNLTQHMRTGLL
>NZ_CP024985|143990:192902|143990_145598_-|WP_030240015.1|transposase|DBSCAN-SWA
MMVLVMQTDAPFWDSLVFDGIDDVGVEAVTVAFGTVEVVARGRMAGAACPDCGRFADRVHDRYQRRLKDLPLAEQGFVIRLMVRRFICGSADCPRRTFAEPFSRLAAPYPRFTTRLNRALERVGLALAGRAGARLAAQLGFGAGRMTLLRRVMALPDPRFSTPRVLGVDDFAIRRGQTYSTVLTSVEDHRVVDVLPTREAGPLAAWLDCHPGVEIICRDRAGAYAEGARRGAPDALQVADRFHLWQGLGRAVETCVAAHRDCLRTPAPSGTLTEATRPTSGGSQDDAEPVGRRAARKKAAHALVDEMLAQGHSRRAIARHLGWGLNTVLRYANASRWQDTIRENRPRPSRLDPYKPYLERRFTEGCTSVTQLHGELVAEQAPVTYGMVRAHIATLRRDPSAAPPRPATVRQVTGWLTRHPATLSEEDRIGLKDLLTRCPELDTAAGHVRDFGEMLTDRLGATLPAWIDAVEASRLPGLTGFALHLRRDLDAVIAGLTLDWSSGSVEGAVNRIKKIKRQLYGRAGFHLLRKMILLR
>NZ_CP024985|143990:192902|168914_170072_-|WP_030240064.1|DBSCAN-SWA
MTWLTDRAVVLATACFYALMLCWSIRRGPGLFRFPGLGPFQMMGLCVVLALPVLLMRRLPAAVFAAILGESVLGDLFGVRPLIVFVLLVFLGGHLAVRRPKAAAVGSVAAVAAAFVENIHVYPGETVSDAAQWAGQFALWFAVAWVFGGVYRKRREYLGALHEQRAARAVMAERLRIARELHDSVAHSIGIITVLSGAAARVVETKPEQTRQALTGIESTSRQTLLELQRMLGALRRAEPDDAMPGAAPLAPAGSLADIPRLAERTADAGVRVHVAWRGERRPLPPEIELSAFRIVQESVTNVVRHSGARTCRVAVGYEPTGLRIEVVDDGDDSPGPGRPRPSATAGGSGFGLLGMRERVTLLSGQFSAGRRPEGGFRVAARLPA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_030240015.1|143990_145598_-|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_158740946.1|146405_146684_+	hypothetical protein	NA	NA	NA	NA
WP_051841446.1|148580_150068_+	two-component sensor histidine kinase	NA	NA	NA	NA
WP_106979791.1|150439_151438_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_030240024.1|152348_152561_+	hypothetical protein	NA	NA	NA	NA
WP_037688841.1|152627_153110_-	hypothetical protein	NA	NA	NA	NA
WP_100661221.1|153599_154013_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_158740948.1|154624_156022_+	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_030240035.1|156216_156543_-	hypothetical protein	NA	NA	NA	NA
WP_030240039.1|159090_159402_-	hypothetical protein	NA	NA	NA	NA
WP_158740950.1|159600_160329_-	hypothetical protein	NA	NA	NA	NA
WP_030240041.1|160325_160979_-	hypothetical protein	NA	NA	NA	NA
WP_106979792.1|160997_161444_-	hypothetical protein	NA	NA	NA	NA
WP_100660732.1|161586_162051_+|transposase	transposase	NA	NA	NA	NA
WP_158740952.1|162356_163091_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_159038048.1|163433_163634_+	hypothetical protein	NA	NA	NA	NA
WP_030240054.1|164258_164621_+	hypothetical protein	NA	NA	NA	NA
WP_158740956.1|165354_166023_-	hypothetical protein	NA	NA	NA	NA
WP_030240059.1|167547_168156_-	hypothetical protein	NA	NA	NA	NA
WP_030240062.1|168240_168918_-	response regulator transcription factor	NA	NA	NA	NA
WP_030240064.1|168914_170072_-	sensor histidine kinase	NA	NA	NA	NA
WP_030240065.1|170253_171459_+	acetylhydrolase	NA	NA	NA	NA
WP_078950784.1|172363_173299_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_158741059.1|175121_176687_+|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_030242091.1|176803_177898_-	hypothetical protein	NA	NA	NA	NA
WP_158741079.1|179577_180273_+	hypothetical protein	NA	NA	NA	NA
WP_030242206.1|180725_181046_-	GYD domain-containing protein	NA	NA	NA	NA
WP_158741081.1|181840_182218_-	hypothetical protein	NA	NA	NA	NA
WP_030242208.1|182735_185528_+	hypothetical protein	NA	NA	NA	NA
WP_078950792.1|185547_186132_-	DDE endonuclease	NA	NA	NA	NA
WP_100660733.1|186128_186611_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_167456779.1|186796_188449_+	hypothetical protein	NA	NA	NA	NA
WP_100661220.1|189488_189872_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.4e-21	40.2
WP_159038049.1|191195_191798_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_100660736.1|192062_192902_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.1e-10	38.0

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP024985|209435:263667|DBSCAN-SWA
TATGAGGTATCCGCAGGGTGGGGGTCTGACCGCGGAGAGGCAAGCATTCCGCGAGCGGGTCCGGATGGAAGCGGTCGCGATGTTCGCCGTCGGGCGGGGCAGTGGCGAGGTCGCGAAGGAGTTACGGGTCAGCGTCCGGTCGGTCCAGCGGTGGCGGCAGGCCTGGAGTGCGGCCGGTCAGGACGCGGTCCGTTCCCGCGGCCCGGCGTGTCGTCCCAAGCTGAGCGACGCGCTGTTCGCCGTGCTTGAGGAGGAGCTTGCCAAGGGCCCGGTCGCGCACGGCTGGCCGGACCAGCGGTGGACGCTGGCCAGGATCAAAACCCTGATCGGCCGCAGGTTCCACAAGTCCATGACGCTGTCGGGCATCTCCCAGATGCTGCGGCGGCACGGCTGGAGCCACCAGGTGCCGGCCCGTCGGGCCGTCGAGCGTGACGAGGCGGCGGTGGACGGCTGGGTGAAGGACGTGTGGCCGCACGTGGAAACACCGCGGCGGCGCTCGAAGTCTGGATCGTCTTCGAAGACGAAGCCGGATTCTCGATGACGCCGCCGACCTCACGCACCTGGAGCCGACGCGGCACCACACCCGTCATCCGGGTCCGCGGACGCTCCCAGCGCCGCTTCTCCAGCGCCGCCCTGTGCTGCCACAAACCCGGCGAACGCTCCCGCCTCATCTACCGGCTCAAACGGCATACCGATCACAAAAGCGGAGGCCGCAAGTGCTTCGCCTGGACCGAGTACCGCGACCTCCTCATCGCCGCCCACCAGCAACTCGGCGGACCAATCATCCTCATCTGGGACAACTTGAACGTCCACAAAGAGCGCCGAATGAAGGCCTTCATTGACGCGCAGGACTGGCTCACCGCCTACCACCTGCCGTCCTACGCACCCGACCTCAACCCCGTGGAAGGCATCTGGTCAATCCTCCGCCGCACCAGCCAGGCCAACACCGCTTTCACCGACCCGAGCCACCTCATGCGCCGACTCCGACACGGTCTCCGCCAGATCCAATACCGCAGCGACATCATCAACGGATGCCTCACCGCTACCGGCCTCATCCTCAGGTCCGGCTCCGACGGGCCATACTGCGAGCCGCCGCAGCATGCGCTCCTGTGAAGCCGCGCTCAAGGAACCGGATCTGGAACCCCGCTCATTGGCCGAGTACGCGCTCAGCCAGACCACGGGACCGAGGACCACACGCCGAACCACTGCTCGGCGTCGAACTCCTCGAACCGCTCCATCTCGGTGAACCCCAGTTTCTCCGCGACACGTACCGAGCGGTCGTTGGCCACCTGGGTGCAGAGCACCACCGGCTCACCGGGAAACACGTCGGCGAACCAGCCGAGCGCCGCCGAACATGCCTCAAGAGCGTACCCACGTCCCCACGCCTCCGGCAGGAGCATGTAGCTGAGCTCGGCCTCCCCGGCATCAGGACGGACGTGCCCCGGACGCTCCGCGCCCCGCCGGTCAAGCGTGACGATGCCGATCATCGCCCCGTCGTGATCGACCACGAATACGCCTGGGCGCCGCCCGGGCACTTCAGGCACTGCATTCTCAAGCTCAGCACGCGGTCGGGGGCCACCGAGGTACGTCCGCACCTCTGACGAAGCGAACAGGTCAACGAACGCCGCACGGTCTCGGGCCTCGGGCTCGCGGAGCACGAGCCGCTCGGTCCGCAACGGGGCGGGCGGCCAGACAACGGGTCCAAGCTCAGCCATGACAGGTAACCTACCGACTTTCCCCCATGGCGGGAGCACCAGGCCCCGACATCACGCCTTCAACCTCAGTAACCGACTCCATGCGGCGTGCTGTCGCCGTCGTGGCTGGGCAAGAGCCGGAACCGACGGCGGATGGGCGGGCGTCCAGTCCTAACAGCAGGCATGAAGGCTGCGAGCCCGTCCGGAAGCGGGCCGGAAAGCCGGCCCGCCAACCGTTCGATCACCGGCGCGTGTCGATCCGCACCGCCGTAAGGCGTTGGTATGCCTGCAAGTAGAGCCGGTCGTCCCGGTGGGTCAGGTCACTGGGCCCGTCGGGCATGCCGGCCGCCTGTGCCGACAGGGTCCACGAGGCGCGGCGCTGTGCCAGGTCCACCGCGACGACCGCCTGACCCCCGCCGCTGACCGCCGCGTACAGTTCGCCTCGAAAGGGCCCCGGGACGGCGATTCGCTGGAAGGAGGGGCCGGGCTCGTAGGTCCAGAGTTTCCTGCCGGTCGACTCCTCGAACGCCGTGAAGGCATGCGAGGCGATGTGGACGGTGCCCTGTACGCACACCGGGGAGGTCAACAGGGTCTGATCGCGTTCGGGTTTGAGCGTCCAGGTGGGGGCGCCGGTCAGCAGGTCGACAGCTGTGATGACCTGGCTGACGTCGAAGACGTGGTGTTCCGAGACGACCGGCGGATAGACGCCTCCGGATGCCCCCGGAGCGGCTGCTTCCGCGTCGCTGCGCAACCTGGTGACCCACAGGAAGCGGCCGTCACGAACGTCGACCGCGAAGACGCGGGTGGCGTCGGAGCCGATCAGGCGCCCGTTCGCGACGACGGCGCGGAAGTACAGCGCCTCCGTCCGATCGGTGTATCCCCATGCGACGCGGGTACGCCAGCGCAGCCGGTGCGCGGCCAAGTCGTAGGCCAGCAGCCATGGTTCCGCACGGTCCTTGTCGGCCTCGTAGTAGGCCCTGATGTAGAGGGTGTCCGCGTCGGCGTTCAGAACCTCGCTGTACAGGCTCAGAGCGCCCAGTTCGTGTGGGCCGGCCGCGTCCGGCATGAGGCGGCCGGAGAGCGGGTCGAGATACCCCGCTGCAGGCGTGAGCTCCTCGTCGAAGGCGAGGGCGGCGAGGCGGCGGCCCGAGGCGGCGACCCGCAGCCTCGTGCTCGGCACCTCCCAGAGCATGCCGCCGCTCGTCGGCGACAGGCCGCGTACCGTCTCCCCGGGGAGGAGGACCAGTTCCTCGGTGGCGACCGGCGGACCGTAGACGGCGGACACGGGAACCGACCACTGCTGACGGGGAGAGCCGCCGGGAAGACCGCCGCTCGGGGACGGTACCGGCCCCGGCGCCCCCGATCCCCCTCCGAAGCCCGGTGACCTGCCCGTCAACCACAGTGCCGAAGCGCCGCCGGCCGCCACGGCCGCGGCGCCGGCGAGCAGCACGCGACGGGAGGGGTACGAGGGGCGCAGGGGCGGGGAATCCTCCCGTAGGGGCGTCCCGCCCAGCGACGCCAGTTCGTCCACGCGCCGCGACATGTCGGCGAGGACCTCACCCGGTAGCGACTCGGAGAACCGGGCGGCCTCGTAGGGGCCCCAGTGCGCAGCCAGCTCGTCGAGGGTGGGGCGGTCTCGGGGATCGGGTGACAGAGCGGACCGGATCACCTCCCGCAACGTGTCCGGCACCCCCGTCAGTTCCGGGGGCGCCCCGTCGCGCAGCAGCCGCAAGGCGTCGCGGCCCGGCCCTCCGTCGTACGGACCGTGCCCCGAGGATGCGAACACCAGCACGGCGGCCAACGCGAAGACGTCCCCCGGCGGACCGTGTTCCTCCCCTCGGACCAGCTCCGGTGACATGTACGAGGGCGTGCCGGCCGGCTCGCCCGCCGCGGTGAGCGGAGGGCCGCCGAGCGCCCGGGCCAGACCGAAGTCGATCAGCTTCGGGCCCTGGGCAGATATCAGCAGGTTGGCCGGCTTGAGGTCGCGGTGGACGAGCCCGGCACGGTGCAGGGTGGTCAGGGTGTCCGCCACTGCTGCACCGAGCATGACCACGGCCGCGACCGGCAGGGGGCCGGCGACGGCGACCGCCTCCGACAACGACGGTCCGATGAGGTACCCCGTCGCCAGCCAGGGAAGGGAGGCCTCGGCGTCCACCGCGAGGAACGCGGCCGTGTGGGAGGAGCCGAGCAGCCGTACGGCTTCCGCTTCGAGCAGGAGACGGTCACGGAAGCCCGGCCTGTCCTTGAGTTCGGTGCGGACGGTCTTCACGGCGGCCAGGCGGCCGCTTCCCGTCCGTGCCAGATAGACCGTCCCCATGCCGCCACCGCCGACGCGGCCCATCAGCGTGTAGGTGCCCACCCGAGCGGGATCGTCGGGGAGGAGGGGGAGAACCAAGGGCACGGGGCACCATCACTTTCCTTGGGGGCTGCCATCGCTAGACAGCCGGCAGGGCGAAGACCACACTCGGCTGGGCGACGATCAGGACGTCCGGCGTCGCCAACAGCTGGAGGGGGCTGGGGTCCTCCCGGCCGACGAAGGCCATCTGCCACAGCCGTTCACCCGACCGCAGGTCCAGCGCCGCAAGCTGCCGTCTGGTGGGGACGAACAGGGTGCGGCCCGAAGCACTCGTCGCCATGGTCCCCAGCAGGAACCACTGAAGGGGCTCGTCCAGCCGTTGCTGCCACACCGTGCGTCCGGTGTCCCTGTCCAGGGCGACGACTCCGTTGACCGGATCCGTCTCGCACAGCAGGGTGCCGGTCAGCAGGAGCGGGCTGTGCTGGCCGCCGAAGCGCAGGGTGGACTCCCACAACTGACTCCCGGGGGTGGCGTCGTACGCGCGGGCCCGGCCGGTGGAGAGGACGTAGAACCGGCCCGTTTCGTCAACGGCGGAGGCCGGACCGCTGTACACGCCCTCGTACGTGCGCTGCCAGAGGGACCTGCCGGTGGTGCGGTCGAAGCAGGCCAGGGGCACTTTGCGCGTCCCATAGGGATCCCGGTGGGGGTCGACTTCGGGGAGCACTTCCACGAGGAGCCCGGCCGGCGTGGGCGTGAGGGACAGCTCGTAAACGAAGTCCGCGGGCAACTCGCTGCGCCAGAGCTCCCTGCGCGCCGCAAGATCGAACGCGGCGAGGGCGTGGGTCGTGGCGGAGGCGCCGGCGGCAGGACCCATGTGCAGCCAGACGGTGTCGCCTTCGACTGCGAGTAATTCCAGGACGGTCGTGTTCTGTGTGTGGAACGTTCGGTCGATCCAGTGCGTCCGGCCGTCGCCCAGCGAGCACAGCACGAGGGCGTCGCGGGTCTGCACCAGGATGCGGCCCCCGCCGACGAGGAGTACAGGGTTGGCACGGCCGAAGGCGATCGGCCGCTCCCAGACTTCCTTTCCGCTGCGGACCTCATGGGCATGGAGGGTCTCGCCCCGGGTGACGAGGTAGCGCCCGGCACCCGCCACCCGTAGCAGGGTGGTCCTCGCGGTCACGTCGTCGAAGCGCCAGAGTGCGGTGGGCGGCAGTCCTGGCAGCGGGGCCGTCGCGAGGGGGCGGTCCGGTAAGGACCGGTCGGCCGGCTCCCGGGTCGCCGTCCAGGCAAGGGACGTACCCGCGCCCAGTACGGCGCCCGCCACGCCCGTGGCCAGCCGGGACAGGAGCGCTCGCCGTGTGAGCGGGCCAGCTGGGGAAGTCTGTCCGGTGGCGGAGGAGCGCGTCGGACCGTCCGCGGCACGGTGGAGGGGCCGAGTCGCGACATCCGTCCGGCGCGGGAGATCGCGGTCCGCGCCCTCCCCGAGATCCGCCGTCTCCTGCGCCTGGGCCGCGAGTGCGATGATCACCTTCCCGGGGGCGGGACCGTCCGCCACCGGGGTCGTCCTTGTGAGAGCGGACGTCTGCGACAGCTCGGCTGCGGTGGGACGGTCGCCCGGCACGGGGGCCAGAGCGGCGGCCACGGCTTCCGCGAGATCCGCCGGGAGCCCGTGTAACTCGGCCTTCCCATGGGACGCCCGGTAGGCCAGGACCTCAGGTGGACCTTCACCGAACGGAAACCGTCCCGTCGTCGCGTGCGCCAGCAGCACGCCCAGGGCGTAGATGTCGGCGGCCTGCGACGACACCCGGCCGCCGACTGTCTCAGGTGCCATGAAAGGGGCTGGCAGGGCCGACGGGGGAACGATCTCCTCGTCGCGCCGCCCCCGTTCGGCAGTCGGGCTTGTCCGGCAGGAGGACAAGGCCATCAGCAGAGGGCGCCCCGTCGTGAGCCAGACACCCGAGGGGACCAATGCGCCGTAGCTGACACCCTGCTGGTGCAGACCGGCCAGGGTCTCGCAGAGTGCGCCGCCCAGTGCACGGATGCGGTCCGCCGGCTGCGGTTCGAGTGTTCCGGTCGTGGAGCCGGCGACGGCGGCGAGGGTGACGGCAGGTATGTGGGCCAGGGAGGCCCACGGCGGCTCGTCCGCGGTGTGAAGCTCCAGTACCTCGGGAACGCCTGGCACCGAAACGCCGGCCAGGAGCTCGGCCGCCGCGCATGCGGCGCGAGGAAGCATGCAGATCAGGGCGTGAACATGCGCGCGGTCACGGCCCAGGTACATGGCCGGCGATGTGGCGGGCCGGGATGGGCGACCGCGTGCGGCGGGCCCCTGTTCCGCTCTCGGCTCAGGCCCGGAGCGCGCCGCTCCCGGGCTCGGCCATCGGGCGAGCACCCGGTACGGTCCGACGGACCTCGGGTCGCCGTCGAGCAGCCTCTCCATTACCCGTCCCCCTCATCGGCGGCCCTCACGGGGCCGTTTCACATGGCCGGAATCGCACTGACGCTCGAACCGCGCTGCCAGACCACCCTGCCTGCGACCGCGGCCCCCTGCCAGGGGGCCGCGGAGGCGATCGCCGGAGCGAACACGTACTGGGCCGCTGCCCGTCCGGTATGCACGGCAAGGACGCCCAGTTCGGGATTGGCGAGGGCGGCGTGGACGCTGGCGCCAGCCACCAGCGGCCCCGGGCGCGGGGCGAGTTCGGCGCCCGCGGCCACCGTCCAGGCCGCCTTGCCCGTCACCGCGTCGACGGCCCTGAGCTGAGCCCCGTCCCGCACGTACAGCTTGTCGCCCGTCGCCGTCGGCTCCCCGAAGCCCGCTCGCTCGTCGGCGGCCAGCTGCCACAGGCGGCCTCCCCCTCTCGGCGCCAGGGCGGTGAGCGCGGCTCCGCCCCCCAGCACCACGGCCTCGCTGGACATGGCGGGCCGGCACGCTTCGGTGTCGGGCGCCGGCCTGTCGGCGCCGCTGATGTCATAGCGCCACATCCGTGCACCGTCCGCCGCGGACAGGGCTACCACGGCCCCCGTGGCGGACACCACGGTCACCAGACCGTGCCCGCCGGCCGCCGCGACCGGGCCGGGTACGGGCAGCTTGCCGTGCCAGCGCTGGGTACCGTCAGCCGACCGCAAGGCGCGTATCTCGCCCGAATGGTCCAGGACGTACACGGTTTCACGGTCGACCGCCAGCAGACGGTCGGCGTCTGCCTTGATCCTCTTGAGAACCGCACCGCTGGCCGCGGCCAGGAACAACACGGCCCCGTCGGTGTCCAGCGCGACGGGACGGCTCCCGCCCAGCACCTCTCGTACGGCGGGGCCGCGCCAACGCCGTCGGCCCGAGACGATGTCGTAGGCGGCGAGCCCGCCGCCGCGCTCCTCGAAGTACGCCGCGCCGCCGATGTCCCCCGGCGGATAGCGTGGCGTGACCGCCGCGCCTTCAAGCGACCACAGCACCGGCGGCACCTCGCCGGGCTCACCGGACCAGCGGGGCGCGGGATCGTGCCCGGACGGCGACTCCGAAGAAGACCGGCCCCAGACCAGAGCCCCTACGGACGCGCCCCCGAGGACGACGGTGGCCGCCCCTGCCGACAACACGTTGCGCCGAGTGATCAGCCCGGCGCGGCCGGCCAGCGCGGTCGCGGCTCGTTCGATCTCCGCGGCGTCGGCGACGACGCTGGGCGGGAGCCAGCGTTTCGCCGCGCCCGCGCCGACCCCTCTCGGGTCCAGTTCGGCCGCGATCTCTGAGGCGGTGGGCCGATCGGCAGGCCGTTTCTCCATGCAGCCGCGTACCACCCGGGCCAAGGTGCCCGGTACGTCTTTGAGATCGGGTTCCTCGTGGACGATCCGGAAGTCGGCTCCGGCCTGATCACCGTTGTAGAACGCGTGCCGTCCCGTCGCGGCGAAGACGAGCAGCGCTCCGGCGCAGAACACGTCGCTGGCCGGTCCGAGCTGTTCCTGCATCACCTGCTCCGGTGACATGTATCCCGCTGTCCCTGGACGCTGTCCGGCGCTGGTGAGGGTGTGGTCCCCTGCCATGCGCGCGATACCGAAATCAACCACTCTAGGGCGGTTCAGGGCCATCAATACATTGGACGGCTTGAGGTCCCGGTGGACGACGCCCGCTGATTCCAGCGCCGTCAGCGCTCGCCCCAGCGCTCCGGCCAGGGCGCACACCGCGGGCACGGACAGCGGCCCGTGACGGCGTACGGCCTGTTCGAGGGTGGACGCCGCGACGAACTCCGAAGCCAGCCATGGCACTGCGGCCAAAGGCGCGGAACGAAGCACGGCAGCCACATAACGACCGCGCACCGAGGCCGCGGCGGCCACTTCCCGGGCAAAGCGGTCTCGCAGCGCCTGGTCGTTCAGCAACTCGGGACGGATCGTCTTCAGAGCCGCCCGCCGGCCGTGGCCCTTGGCCAGATATACCGTCCCCATGCCGCCTGCGCCCAGGATTCCCAGAATCCTGTAGCCGCCGAGCTCCGCGGGCACTCCGCTGGGCAGTGAGGCGATCACTGGCGTCATGGTCCCGCATACTAGATGCCCTACTGGCGTGGGCACCAGGCAGGCGCAGCGGGGCACAGCCGGCAAGGGCCGTAGGCACGGGCCTGTGCCGGCAGCGCCGAAAGCTATACCCGACGTGCCCATGGCATCACGAGGAGCGGGGGTGGAGATCACCGAGATGTTCCAGCCCAGGCCGACGAAGGCCCCTGCATCGACGCCTACACCACCGGTGATCCGGTCCACGCCGGCGACCTGACCGCGCACGAGGACAACTGGCCCACCTTCGCCCCCCCTCGCCCTGGCCGCCGGCTACAGCGCGGCCCACAGCCTGCCCCTGCGAGTCCCGTGCCCAGCATCGGGCGCCCTCAACCTCCTCGCCCACAGCCCCACCCCGCCTCACCACGGACGACACCCGCCGGCACCCGCCCCGCCTACGGCTCCGTGCGGGCGCGCTTCTCGGAGCGGGGGGGAGCGGCCCTGGGCAGACGACGCCTACGGCTTCGTCTCCGGTGTCGAAGCCAGCGTCGTAAAAGTGCCGGGTCCGCGTATTGCCACGGCCCCCTCGACCACCCGCACCACCTGGGGCCACCGTCGGCTCTCCAGGTCGTGGCACCACATGGGGGGTAAATGGACATCAGCAGCTTCATATCCGAGGACTTCGGCTCGGTCGTGGCTGGGGGAGCGGCCTTGCTGGCGGTTCCCGGCGTCATCGTCGCGGGAGCCATTCAGGGCAAGCGGGCATTGCAGGGGGCGCAGGCGCAGGCCGAGGCCGCCCTGCGGGCCGCACATGAGCAGGCTGCGAAAGCACTTGAGGCCGCGCAGGCCCAAGCCCAGGCGACGCTTGAGACCGGGCGGCTCCAGGCACAGGCCACTTTGGAGGGAGTCCGGGAGATGTCCCGCGAAGCTCACGCCCAGTGGCAGCGCGACCGGTGCGAGGATATCTGGGCCGCGTTCGTCGCGGAGCTTGACCTGCTGAAGGCGAAGGAACAGGCAACGAGCCACGAGTCGGAGGTGGCCGACTTGTTGAAGGCCTACGCCATGGTGGAGCTGATGAGTCCGCCCGTCGTCTTGGAGCAAGCGAGCCGAGCGAGGAACAAGGCAATCGAAGTCGACCTCATGCTGTTCACCCTGCGTATGCAGGCCAGGGACATGGAGCAGCTGGAACTTGCCAAGCAGCGGCTGAGGTCGGACGTGACACAGGGGTCGGGCATCGCCGATACCCGTGGGCTACTGGCTGAGCTTGTACCCGGGCCGGACGGGGACGACATGGTCGATTCGCCGGGATCACCCGAAGAGTACGAGGACATGCGGGAGCGCTTCGAGAGATGCAGAGCAGCCAGTGATGCCCTCGAAGCCTTGGCGGCGGTCGAGCGTGCGCAGGGTGTCCAGGATGCCGGAGAACGGGCGCGTCAAACCCTTCTTGCTGCCGGGTTCAGGGAAACGCAGGCCAGCTCGCTCGTGTTCACCGCGCAGCTCGACCGGGACGAGCAGCAGCAGATCCTGGCTGCCGACAAGAGGGAGCTGACCCGGCTGCGCAACGTCTTCGTGAAGGAGGCCCGCAAGGAGCTGGACGCCCTCGGCGCATAGACCAGCACGCCCCCTCCTTTCACAACGGTGCGGGACGGTCAACGGTGGAGGCCACGGGGACCCGATACGGGTGGGTCGTCTCACCCTGGCTCCCCGGCGTGGTGCGTGGCCGGCACCACTGCGGCCATCGCTGCCCGCCGTGCTGCTCGGTGCTGCGCCAGGGGACCGGCCCCGAGATGCCGGCTCGCCGAGGGCGACGTCCGAACTGACCAATCCTCCGTTTCCACAGTGAGCGCAGAGACACCCTTCGGAACTCGCGCTGGTATCCGAGACGAAAGCGCGGCGGTCGCGGCGGCGCGAAGCGGACACACGCTGGAAAGCTTGAGGTTCGCTGCAACGCGAACAACCCATTCGTACGACACGGCCCGCGAAAGGATGCAAGTTCGTGGCTGCAGCAACAGCCGGGGCAAGTCGATCCGCTACTCTGCTGGGGCGGCAGCCCACGCCTGCCAGAATTCCGCCCGGATCAGCTCCCACGCCCCGGACACGGACAAGGGTCCCGGACTCGCGTTCAGTCGTTCAAGCCGTTGCCGGCCTTACTGCGGCATGGGCGTGGGCATGCGGCGTGAGGAAGACCATGACGCAGGACAAGAAGCGCAAGGCGGCCGCGCGTGCGATGCAGCAGGCGGCCGGTGTGCGGTACACGACGGCTCAGCGACTGGAGGCTGCCTCCAGGAACGCGAGCGGACACTCCGACAGGGATGAAACAACCATGCCCGCGGGCTTGGTCGCGGGACTCAACGCGAGCGCCTACGAAGCCGTCCGAGACCTGACCGATGCCTTGGAGTACAGCCAAAAACGGCAATCCCTTCAACGTCCCGCGGATGGTCCTCTACCGCTTGGGCGACGCCATCGACACCCTGTCCCAGATCACCCGGGTGGTCACGCAGGTCTACCGCGAGAACGGACGCGCCGAGCACGACCTCAACTCCTATCGCCAGCCGCTCCAGGAGCGCTCCCGTACAGACAGCCTCGACGACAGCGACCACCACTACCTCGCGGGACTCCTGGGACGTCCTCTTCCTGCGGACAACGGGTCGGCGACCGGGCTCTACGACTGGGGTCGTTCGGAGGCCGAGCACCCGGACCTCCCCGAGGTGGTCAACACCCGGGCGTGCCTGTACGCACTTCGCGCGAGCGGCTCGGAGGAACCTGAGACGGTCTTCGCCTCACTCAACGAACCCACCCGTGCCGTGGCACGAGCTGTGGCACAACATCTGCTGCCCCCATGCGACGATGACCTGCCCTAACGTCCACGCGGACGTCGGCAGGGGGGCCGGTGAGGGCGGCTACCTCGACCCTGCCGAGGCGGAGGAAGCAGGCGCGTTTCTGCAGTGAATCCCACCGCCCGCACGAGTGAGTTGTCCGCCGAGGGCCTGTCGGAGCGGGGGTCTGTACCGCTAGACCGCCTGTTCAGGGGAGGGTTTGTAGACGACGGTGGTGGGGCAGTCCGGGGCGAGCCACAGGAGTGCCCGGCCTGCCGCTCGGCCCCGCCGGGCGGGCGGCCGCACCCACAGGCCGCGCGTGCGTAGCCGGGACCTTCGTCCTCGGGGTGGTTGGGCGGCCCGGTGCTACTGCCACCAGAGCGCTCTGGTCACCGGGCCTCGCCCGCGCACGCCCTGTCGACGCGGACTGAACCGACCATAACCACACCCGGCCACCACCCGGCATCACAAGCACTGCGTTCGGCATCCCGCGTGACAAGCGGAGGCGAGAGTTGACGCCCGCCGCTGACACCGGCCACTCCCCCGCCGCAGCTCTCCATCTTCTCGCATCCCCGTACCGTCCACCGGCAAAGAGTCCGGATGCCGCAGCGGACGAGCCCCCGGCCGTCAGCCGGTCGAAAGTACGCCGGAGCCATGGCCCACCAGCGCGGAACCAGGCGGATCGCCAGCACCGCCCGTCTGCTCCCGGGCAGGCGGGCGGTGCTGGCATGCCCCCGCAGCCCACCGCGCAAGGGGCGCCCGCCGGCTGCAGCCACGCCGGAGTCCGCTGCATCGCGCCCCTGATCACGCCCTCCCCTCCGTCCGAGAGCAGGCGGACAGTATCGGCTTCCAGATCCGGCCAATGAAAGGGCAGAGCATGTCACCCTGCGGAGTCGTGAAGTGGTTCGACCCTGACCGGGGTACCGGTCTCATCAGCCAGGACGGGACCGGACCGGACATCCGGGCCGAAGCCCGGGCCATCCACGGAAAGGGCCCCTGTCTGCGACCCGGCGACAGAGTCCTCTTCGACCTCACCCACGACAGCGCCGGCCTGCGTGCCGACAACATCCACCGTCCGGAGGATGCCCTCAGCCAGGACGGACCAGGGCAACAGACGGACAGACGCGGCAATAGCCGGCTCTAGGCAGTGTCTGATGGCTCTTGCCTGGGATGGTGGATCTATCACTGTTCTGGGCAGGGGTCTGGCATGGTGCGTCGGCATGAACTGACGAATGCTCAGTGGGAGCGCATAGCTCCGCTGCTGCCGGAGACCGGGAACCCAGGTGGGCGGTGGGCTGATCACCGTACCGTGGTCAACGGTGTGTTCTACCGGACGCGGACAGGGATTCCGTGGCGTGACCTGCCTGAACGCTACGGAACCTGGCAGACGGTCTACGAACGCCACCGCCGGTGGTCGGCCGACGGCACCTGGTCGAAGATCCTGCGCGCTCTGCAGGCCAGCGCCGACTCCACCGCCCAGGACGCGGACGGCTCGTGGGCAGTCAACGCCGACTCCACCACCTGCCGGGCCCACCAGCACGCAGCCGGAGCCCGGCACGCTCCTCCGGCCGACCATCCTGAAAAGGGGGTGGCGCGCGTGTGGACGGAGATGGCCGTGAGGCCCTGGGACGCTCCCGGGGCGGGCTGACCAGCAAGGTCCACCTGCTGACGGATGACCGCTGCCGGCCCCTGGCCTGGCTGACCTCGCCCGGTCAGCGTGGGGACAGCCCGATGTTCATCCCGCTCATGCAGGCCCTGAACGTGGCCCGCACCGGGCCAGGACGTCCGCGGACCCGGCCGGACCGGGCCCGCGGCGACAAGGCCTACTCAAGCCGCGCCAACCGCGTCTACCTGCGCAAACGCGGGATCAAAGCAACCATCGCCCAGCCGGACGACCAGCGTGCGAACCGCCGCCGCCTTGGTCGGGCCGGCGGCCGCCCACCGGCCTTCGACCGTGAGCAGTACCGCCGGCGCAACACCGTCGAACGCTGCATCAGCAAGCTGAAACAGCACCGGGCCGTCGCGACTCGGTACGACAAACGCGACTACATCTTCCACGGCACCCTGGCCACCGCAGCCATCGTGATCTGGCTCCGCGACCTCACCAAAGAGCCATCAGACACTGCCTAGCCACGGCCACCTCGGGCTCCATGGGGCGTGCAGGATTCCGTCGGCCTACGGATATGCCGTCGAGCCGATCAATGGCCGAACCTCGCTGCTGTGCCGGGGCAGGTCAGTAGCGCTTGACCAGAACCGAGTTGGAGACCTTGCGTGCACCGTTCGGGAGTTTCAGGAGCGATCCGTCCGGGTTCCGGTTGTCGCTCAGCTGTCGGTAGGAAAAGTCGTCCGTGAGAACGACGTAGATCGTGCGGGCAGAACCGGGCACGGCCTGGGACAGGTGGACATCGAAGGTGTACGGGCCGGGCCGCCCCAGATCATCCTTGTGATAGTAGTTCGTGTGCGGCACGGGCTTGCCAACGCCGTCGATCTGCACTATCCAGCTCAGATGCAATCCGGCCCCGAGGGTGCAGTTGACTTCAGCGGTGAGGGACCCGTCCGATGCGACCGTCAGCTGCTTGGGCTCGACGGTCACATCCAGTCCCGGCTTGCCGCCGCAAGCGGGCAGGACCTGTCCCGGGCCGGCACCGCCGGAGGAAGGACCTGCCTGTGATGCCGAAGGGGCGGGTTTCGGATCGTCGCGGTCGTCCTTGCCGCTGAACACGCCAGACCACAGTCCCAGACACCCCACGATGATCGAGCCCGCCACAGTGAGGATCGCGGCCCTCATGGTCACAGGCTCACCAACTGCCGATCCAGCTCATACAGCCCCCTCGATCCCCCGGCACCGAAGCCCTCGCCTACCGCAGCGACTTCGGCGCACCCCCGCCACAGGCGGGACGATTTCTCTCCCCCTGAAGACGATAACAACTTTCTGTAATCGAGTAGATACAAGAATGTACTGGTCGGGGTCCAGAGCAGCACCCCTTTCGCCGCCCGCCCCTCCGCGAGCCCGCCGTACAGCAGCCCCCTGGACCGCAGCACCGAGATCCGCGAGTCCTGGGGCCCAGCCGAGGCGGACACCTCTCCCTTCGCAGTTCTGTCCAGCAGCCCGGCTTCAGCCGGTCGCGCAGGCCCTGCTCGCCTTCGGGGCCGCGGGCGACGTCGGCCATGCGGGCCGCGAACAGGGGCCAGGCCCGGGTACTGACCAACAAGGGCCGTCTCCCGCTCAGGGCCGATCCAGTCCTGCGCACTGGTCACCAGCCGGCTGTTCGTCGCCGCGCCGACGCCTAGCTGTTGAAGGGCGGCAGGCCGGTCGGACAGGTCCAGATCGTTGGGAACGCTCAACCTCTCGGTCAGCCGGCTCCCACATCGCGCGGGCGTCCGCCCGCCACCGTCCCCGGGGCCGGCCCCGGGGACGGGGCCGGATCAGGAACGGGAGCAGGAGCAGGACCAGAGGCGGCTTCTGGTGCGGCAGGCGCCGCGTACGGATCGGGATTCGGGGCGAGGGCGGACCGCGCGGCGGGCACCACGGCCGCGGGTCCGGCCTCTGGCACGGCGACGCCCGGCCCGGCAAGGAGGAAGGCGACGGCCTGGTCGACACCGACACAGCCGGGGAGCCCGGGGCCCTTCATTCCAAAATGGAGGCACTGGACAATGCCGTACAGGGTCCGGCGGTCACCGGGGACGGCGCAGCGGCGGCACGCGAGACCGTGTCCGAGGTACTCCCCCATCCGCTCACGTCCGGTCACCCGGGCACACGACGTCAGCATGCACAGGCACATCGTCCCAGACGCCCGAACCAGCACCCATCCACCTGACCAAAGAGATAGGGGCCCCCCCCGGGGGCCTTCGTCTTGCCCCAGGGGGTCTGCAGCCCCGTGTCGGTGACGCTGGGTCATCACTCCGGTGGCTGGTGAGGTTGCGGGTGCGGGAATCGGAAGTGAAGTTCTCGGTGAGAGAGCCGATCCGTGCCTCTCGTCTTCCGACTGATCCAGGAGCTTTCATGGAGCGATCGAGGCGATATGAGGGTCCGCGCTGGGCTCGTTCGGCACTCCGTTTGGCTGTGGCGGGCGTCGGGGTCGCTGCCGCGATCACGATGGTGGCTGCGGGGCCGGCCGCGCATGCGACGCCCGCCGGGGGTGCCGTGCCGCAAGTGGCTCCAAAGGCCGGGGAAACCCCGGCTCTGGACTGCTTCCACGTCGAAATCGGCAGCAACGCGACCTTTTTCGCGGTCCGGCCCCTGCTCGACGTGGTCGGGGTCGCCGGGCTCGAACTGCGGGAGCAGGGGAGTACCACCTGGACGCGGATGCGCGAGACGTGGGGCGACGTCTTCCGGCTTGACAGCAACCGTCCACTGCGGGCCCCGTTCAGTCTGCGCTTGACGAACGAACTCGGTGTGACCACCACCTACATCAACATCATCCCCGCGAACTGGACGCCCGAACAGTCCTACTGCGGCACCGGCACCTGACACACAGCCGTAGTGCGAGGGAGCGGCCGGCGTCTGGGTGCGCGGATCGCGCCCGGCTGGTCGTTTTGCCCCTCGTCCGCCAAGGCAGTCCCGGACTAGGGCGGCCAACTGGCCGGGGGCAAGCTGGCCGCGATTGCCCGGCCGGAAGTCGCAGCTGGGGCAGCGCTCGGCCATCTCCCGGACTCGGCCCGTAGAGGGATCCGCCACGGACCAGTGGTAGCCCGGCCCGACCGCGGGACAGCGCAGCGCGCCGTCAGAAGCCTTGGCAGAGCGCGCCCACCCCGCCCCCGCCCCCTTGGACCTTGGGGGCTGCCGGGCTGCCGCAGTCACCCCTGATGCGTGTCCGCAGTGTCCGGTTCAGTTGAGCTTGAGCAGGTTCAAGAGGCATGACCCGCGCCTTCTGCAGCCCCTTGCCCAGCGACCGACCCAGTCGCGAGCGCGCAGCAGAAACGTCCACCCACGCTGACTGGGGCGTGTCGGTCCGCGGGGAGAGCCGTTGTCATGGTGTGAGCGAATGCGACGACCTCGACGACGGGGAATGGGCCGTGATCCGCGCGCTGTTGCCGCGCTGCGGGCCGGGCGGGCCGGATTACCGGGCCGTCGTCAACGGCATCCTGTGGCAGCAGCGAGGCGGCCGGCGCTGGCACGACCTGCCCGCCCGCTACGGGCCCTGGCACCGCTGCGCCGAACGTCTGCGCCTGTGGCAGACGGACGGCACCTGGCACAACGTCCTCACCTCTCTCGCCGCCAGCCGCCCGCTCCCCCGCCGCACGGAGCAGACCCGCGACACGCCGAAATCTTCCCTCGCGCGGGAGGAGATCGACGACTGGAACAGCCCCTGGCTGCCATGACCGCCACCGTGATCAGGCCGCCGTTGGCTCTTCTCGCCGTGTCTGCGGTCAGCGCCGGCCCACCCTCACCACGTCCTCGTCGCGCTCCACCAGATGCCGCGGGCGCTCACCCTCGCGGCCCCGCCCGCACCGCACAGCCGCTCACGCAGCCGTATCAGGTGGGAAAGGCCCGCCACTTCCTTGAACCGGTCGAGAAGAAGGCCAATACGGCGGTCATCGCCCGCCCGCACGGCGACAGCAATGGCGTCGACAAGCTCATCGGGGTCCTCAGGCATGCGGAGAGTCTTCACCGATGCCAACCGATCCATCCCTGTCGCGACCAACAGACACCCGGCGCGCCCATGCAGGATGGCCCCCAGCGCACATCTTCCCCGCTATAGAGCCGCCCCATGGGGATTGCACCCACGCCACTCTAAAACGGCCCCGCACGCCCACAGAGCCAGCGGGCCGGTCTAGCAGGTGCCGTCGGCCGTGGCTGCGTGACGGCGACGTGTGACGGCGGCCGGTGCCCGGCCGACAGCACCCTAAAGGGGAAGAAGCCGACGCGGCGCCCTGCCCATCCCACCCGATCCGGCGTTCACGCACACGCCCGACCCGCCCCACGCCTCCCACAACCACCCGCACAGACCCCGATACCGCCCCCGGCGGGCCGGCACAGTGAGTGCAGAACCGCAGACCTGCCAAAACGGGGACACCAAAGCGTCCGGGCGCTGAATCAAAGGAAGGCCCGCTCCCCCGTTCAGCCGAGTGAGCCAGCAGGCATTCGGATGCGGGTACACACGTGCGGGCGATCCGGAGGAGCGCGGACAGGCGCACCCCGCATCGGGCGGTGTACGGCCGCCGGAGCAGCGAGGGCTCTGCCGGATCCTCGCCAGGTGCACCGAGCCGGACCACCCCGGCGCGTCGGAGGTGACCAACCTCGCCACCGCCGACTCGGTCGAGGAAGCCGCGGTGAAGGTGCGCCGACCGACACCGGCGCCGCGCCATGGACGGTGGTGATCAGCAGCGACACGCGGCGCGGCTGGCTGGAGGCGATCCGCAGCCTCAGTGGCACATCGACTACGACGGGAAGGACGAAGCGGTGGTGGGCCGCCCCGACCCCCTCATCGTTGGCGCCGCAGGACGCCTGCGCAAGTCATAGCTCGTCAGGAGCGGTCCGGCGGTGCCGTAAGGTGGGGTTCACCGACGCGGGGTGGAGCAGCTCGGTAGCTCGCTGGGCTCATAACCCAGAGGTCGCAGGTTCAAATCCTGTCCCCGCTACTGAAATGAGAAGGCCCCGGATCCTCAAGGATCCGGGGCCTTCTGCCTTGTCCGCCGTGGGTTGGATCAGCCGACACGGTGGAAGGTGAATGAGCGGAAGAAACCGCCGTCATCCGCCCATTCCACGTGGAGGGTGTTGCCCTGGGATTGCGTGACAAGGCGGGTGGGGGTCTGGGTGCAAAAGCGCTGTGGTTCGGACGACGTGACCGTCTCGGGGCTGAAGGTCAGAGCGTCGCCGATGGAAGCAAGTACGGAGAAGCCTTCGCAATGGTGGGCGTCGCCGTCCCAGACGAATTCGGCCCGGGCGTGGCCGGGTGTTCCTTGGTTGATTGTCATGCGCACGGATGAGGTGGTGTCGTTTCCGTCCTGGGCGCGCCATGTTCCGATGAAGGGGGCGGGGATCGTCTGGTTTTGTGGCGCGGTGCGGTGGAGGGTGGCTGTGGTTCCTTCTGATTTCCAGGTGAGGTCGGTGTCTCCTTGGCGTCGGAGGGTGATGTCTGCGTTGGTGGTGCAGAGATGGCTGGGGATTCCTGAGGTCGGGTTTGTTGTGAGGACGAGCAGTGTGCCGGCCGAGATGAGGGTTCCTTTTGACTGGCAGAGGGAGCTGGCGGTCGACGTCAGGATGTCCGCGGTCTCTGCGCCCACCGCGCCCTTGCGGATCTCGATGCGGCGCAAGGTAGGGGCTTTGTCTCCGGGCTTGGTGAATTCGCCTTGCCATGTGCCCAGGTAGTCGTCGGGGACCGCCGTCACACTGGTCTCAGTCGAGCGGGTCGGGTTCGGGGGCGAAGTTGGGTCGATCAGGTCCGGGCTCGGGGACGGCGTGGGCGATGCCGGAGGTGAAGGGCTCAATGTCGGGGGCGGCAGGGAAGCCGCAGGGGCCGGTGTGGGCCGGTTCGCCTGTTCCAGGGGGGGGTGCTGCCCGTTTCGCACGAGGGTGACGGCGGCCACCGCTGAGAGGGAGGCGGCGAGCGTCACGGCAACGGCCATCATGACGATCTGGCGTCGGCGGCGCGACCGGTCAGAGGGTGGCGAGACCGCGGTGGGGCTGCGGGGCGGGGAGGTGAGGGCCAGAGCTCCGCGGGGGGTGTTCTGTACAGCTGTCGGCTCGATGGCGTGCACACCCGCTGCCCGGGCGCTGAGTAGCCGGGCTGCGGCGTACTGCTCAACCAGTGCGGCGCGGGAGACGATCAGGATGGCGGAGGCTTCGCGTGAGGCTGCCGTGTAGGGCACAGGAAGATGTTCATCGTTACCGCTCCGGCCGGCGTCGTCGGCACGGGATGCGGCATCTGCTGCGCCGGATGGGTCGTCGTGTGCGGTGGCTTCGTCACGCACGCGGCGTACAGCGTCTTGGACCAGGCGGACTTGGTCCAGTCGGTGGTGTGCTTCACGTAGATCAGTGGCTGCCTGATCGGCGGCGGAAGCCAGTCCAGCCGCGTCGGCGCCCGGTGCCGTGCCGTGTTGTGAGGGCATCTGGAGGCCGGCGATGACGCCGAGGAGGATGTGGACCAGGCGCTCCGCGTCCTGCAGAGCCGCAGTTGCCTGCGCTGCCGCCTGTGCCGCCGTCACTCCCTCCATGGCGGTGTTCGGCTCGTCAGGGCCAAGAGGCTGCTGTGCGGTGGTTGCCTGCTCGTGGAGGCGCTGGGCCAGCGCCCATCTCGCGGCGCGCGCTCGCTCATCTCGCACCAGGTCATGCACGAGGCGTTTGAGCAGGTGCAGGTGGATCGTCTTGGTCCCGGAGCGGTACTCGCCCCAGCTCGTCTTGCTGATCTTGTACCGCTCCGCGAGCTCGCGGACCGTGAAGTCCTGGGTCAGATCTCGCAGGAACACCGCGAGCTCGTTGGCTTCATCGGTTTCCCCCTTGGGCCCGCCCTGTGGACGGCCGGCCTTCACCACAGCGGCACTCCCCCGGTTGGTTGTCCGCGTTGTCCGCTCTTCCGTGTCGCCTGAACTGCGTTAACGGACAACATCTATTGATGGACAATCAGACCAGGTCGGACCGTGGGGCTCCAGCACTTCCCAGACAAATTCCCTGGAGCGTCTCCTGTGGCCCACCTCCTTTCCCGTAACCGAACGAAGCCCGGACCCGGCACGCCACCGGCGCGCCTGCGGCGCATCGGTGTCCTGCTCGCCGGCGCGATCACGGCCGGCCTGCTCTCGGCCGCCCCCGCCTCCGCGGACCCCGCCCCGGCCGCCCCCATCACCCTGGTGTCGGTGACGGCGACCGCTGACGACCAGCTGTACGCGCTCGCCGCCGACCACACTGCCGTCTACCGCTGGAACGGAAAGGGCACCGACTGGACCAAGGTCGGCGGACCCGCCCAAGACCTCTACGTCGGCGGAGCGGGACTCTTCGCCACCAGCCTCGGCAGCGGAGCACTGAACAAGTACAACGGGCAGCCCGGCGACTGGTCTCAGATCGGCGGGGCGGGCGCCGACTTCGCCGTCACCGGCGACCACCTCTACGGCCTGAACCCCGACCGCAGCGCCGTCTACGAATGGAACGGCACCGGCACCGACTGGACCAGGATCGGCGGACCCGCCCAAGACCTCGAAGCCGGCGGAGCAGGGCTCTTCGCCACCAGCCCCGACGGCAAGCTGCACAAGTACAACGGGCAGCCGGACACCTGGAGCGAGATCGGCGGGGCGGGCGCCGACTTCGCCGTCACCAGCGACCACCTCTACGGCCTGAACCCCGACCGCACCGCCGTCTACGAATGGAACGGGAAGGGCACCGACTGGACCAAAGTCGGCGGACCCGCCCAAGATCTCCACGCCGGCGGAGCAGGGCTCTTCGCCACCAGCCCCGACGACAAACTCCACAAATACGACAGGCGGGCCGATACCTGGACCGAGATCGGAAACGCGGGCAAGGCGTTCGCCGTCGGCAGCACTCGCCTCTACGGTCTCGCATCCGATGGCAACAGCGTCCACCGATGGAGCGGCCAGGGCGCGGACTGGACGGCCCTCGGCGCGCCATCGGCCCCCGGCGCGCCGGTGCCTCAAGCGGCGGACCCCAGCCCGGAGCCGCAGTCTGCGCCGCCGGGAATGGGGTCAGAAGCGCAGGACGGAGCAGAGGCTGAATCCGTGCCGGAAGCGGGATCTCCAAGCTCCGTACGGGGGGCTCTATCTGACATCGCCGGTCCTGAACTGTCCGTGACAGCCAAGGGCGATCTCTACGCGCTCGCGCCTGATCACGGCAGCGTATGGAAGCACGAGGGTGACAACCACTGGACGAAGATCGGCGGACCCGCAGAGTCCGTGCACGCAGGGCGGCTCGGAGTCTTCGCTCGCCATCCTGATACCGGCGCCATCTATCGCTACGACGGCGAAATCGGCCGTTGGAGTCAGATCGGAGACGCCTCCGCCGATCTCGAGGTTACGGGTGATCACCTCTATCGCCTGTCCTCCGACCGCTCGGCGGTCTTCGAATGGAGCGGTCAAGGCACCGACTGGACGAAGATCGGCGGACCCGCCGATCAGCTGTACGCCGGCGGCGCCGGTCTGTTCGCCACCCGCCCCGACACCGGCCACCTCTACCAGTACAACGGCACACCCGACCACTGGACCGAGATCGGCACCCCCGGCGCCGCCTTCGCCGTCAGCGACGAACACCTCTACGGCCTGTCCCCCGACCGCTCGGCGGTCTTCGAATGGAGCGGTCAAGGCACCGACTGGACGAAGATCGGCGGACCCGCCGATCAGCTGTACGCCGGCGGAGCCGGTCTGTTCGCCACCCGCCCCGACACCGGCCACCTCTACCAGTACAACGGCACACCCGACCACTGGACCGAGATCGGCACCCCCGGCGCCGCCTTCGCCGTCAGCGGCGAACACCTCTACGGCCTGTCCCCCGACCGCTCGGCGGTCTTCGAACGGACCAGCGGAGACAACTGGCAGTACCGGGGCGGCCCGTCCGAGGCCCTGCAGGCGGTGAGGGACGAGGACACCCTGCGGGAGTTGCGCGGTGACGACTATGTTCGGCAATACCGTCAGGCCAGCATCCTGGCCGACACGAAGCTCATGGAATGGCTCGCGCAGAACGGGGCGGGAATCCTCCTCGAACTCCTCGGCGTCAAGGACATCGAAAAGTGCCTCAGCGCACCCGGAAAGGAAAAAATAAAGCCGTGCCTGCTGGCGGCCGCCAACTTCAGCACCGTCATCACTGCCGTTCGCAAGGCGGACAAGGTGCAAGACGCCATCAAGACGGTGGCCGTAGGTCTTCCCAGGTTTCGCAGCGAGGTCGTCGCCGCCCGCAACGTCGTGGTCCAGGCGCGTGAAATCTTGGACCGGAACGCGAAGGACCTGGCTGACGATTTCACGGTGAACAAGCCCGACCGGGCTGACTGCCGGCGAAACGGCGCAGGCTGGCTCGACCTCGGTACGCGCGACGTCGCACACGGATCCCGCGCCACGGCCATGAACGCCTGCCTCGACACGGCCTACCTGACGGCCCACGCGCAGCGGGGCAGCCCGACGACGGCAGCGGTCAGGCCTCCGGGCTACAACTGGGCAACGGCCACTGCCGGCTACCTTCGCATAAAGGACATTCCCCAGCGCATCAACAATTGCCACCTGCTCGGCAAGCAGCTCACCGGCAGTGGCGAAGATCTGGACAATCTAGTCACCTGCAGCCGAGCCGCCAATGCCCAGGTCAAGGGCGACGAAGGATTCGCCAACGACATGAAGGCCCTGGAAGGCGAGGTCAAGAAAGCCGTGGACGCCGGGCAGGTCGTGCGCTACCAGGTGACCCCCGTCTATTCGGGCCCCCGTACCGTCCCCGTGAAGCTGGAGATCTCCGCAGTCGGCATGTACCCGGACGGCCGCCCAGGCGGCGTTCTCATCAAGCGGGCCGTCGAGAACAAGCTCTTTCAACCGCAGACCCAGAAATGGCACAACCTCGGTCTGTGGGTCATGAACGGCAAAGCAGTCCCCACCGGCAACACGCCCTGAACTCAACCGGCCCCACCTTCCGCTTGCTGCTCATCGAGGACCTCCTGCGCGCGATGAACTCCAGCTTCAGCGGCGGGTCCACACACAGGGAGGCGGGAGGTGCGCGCGGCGAAGCCCACCTGCCGCTCCACATGCGGTGTCCCATCGCGATGCATCACGACGAGAACTACCGCAGTATGGGGACTGTGCAACTCCCTTGCAACTAAGTGAATTTGGGGAACACATGGCTCTGACCGCTCTTGTCTTTCTAGCTGTTCCGTGGCTGTTACTTGCCCTGATCCCCATGCGGAACCCGTCCGCGCGACGCCTTTGGCTCGGGATCGTGCTGTGCGTCTCGATCCTGACCGTCGCGTTCGCGGCCTACTACGGAGTACAGCACACGGGAGACTACGCATCGGATGACGAGCGGCCCTCAGGGGTCATGACAAGCGACGCCGCCGAGGCGTACAGGAACAATGATGCGATCTCACCTCGGTGGATGCCCGTCGTCTTTGCGGCTATGGCCGTGGGACCTGGGGCTGTCGCCGCCCTGCTGCGGCTGGCGCTGTCCAGGCCCGATCGAACGCCCCACTATCCGCCACCGCCGAGCTACCCCCCGGCCCCGTGACCGCATGACACAGCAAGCGTTTCCCCGCCCCCATGGCGCGAAAGACACGCAGGGCAGCCTGAAACGCCGCTCCAGTCCGCACCATCGGCACCACGACGTTCTGCGGCCGGAAAAGGCATCCGGCCACCTGGAGCGGGAAGGCGCCGGAATCCACCCTCAAGGGTCCTGCCAAGGGCCGAGCGGCGAGACAAGGCCGCAAAACGACGGAGGAAGTGAATGTTGTTTTCATTAAGCAAGCCGGGCGTGCCGTGGCGAACGGGGCTGCGCTCCGCCGCCGTGGTATCGCTGTTGGCCATGGGTGCCACCGCCTGTGGCGCAGGAGGATCATCGGACAATCCCCAAGCCGGACAGGCGCCGCAGTCCACCCAGGCAACCTCGACGCCGGACGGAAAGAAGACGCTGGACGCGCCAGTCGCCAAGGGCCTCGGCTCACTCACCAGCGGCAACCTCACCCTGCTGGCCTTCTACGATCCGTCGACGGGCAAGGAGACCTTCAGTACGACGCTGCCGCAGTACTCCGAGAAGAACCCGTGGAAGCGCTACAGCTTCTCGCCGGACTGGAAGCGGCACGCCTGGGTCAAGGACGGCGACCTGTTCGTGGGCAGCTTCACCGGCTCTACGATCACCTCTGCGTACGACGAGACCCCAGGCGTGAAGATCGGCGGCAAGCCCACCTTCAACGGCGGTAAGCGCGCCTACCGCCAGCCCCGCTTCAGTGCTGACGGCAAGAGGATCTTCGCCCTGGCCAATGACGAGAAGGTGTACTCGGCCGATCCCTCGTCACCCGACCAGCTCACCGAGGAAGCGACCCTGGACCAGGGAAGTTTCTTCGGCGGCAGAAGCGAACTCCTGTGGGACCTCACAGCCGACGGCAAGGTCGTCAAGCGGCCCGCCCCTGTGCACCCTGAGCGAGGCGGGCAGGCGACCAGCCCAGACGGAACCAAGACGCTGATCTACAACGGCAGCGGCTGGTTCCTCAAGGCGAACGGCGCAACCGGCGAACCGCAGCTCGCTTTCGAAACACTCACCGACGACACAGACAAGCCTGTGGGAAGCGGCCCGAACCCTGGCATGGACGTGGACATCATCGGCTGGTACTGAGCCGGCCACACACTACGGAAAGCCTCGCATCACGGGTCGATGATGCCAGCGCCCCTGCCGGAGCAGACACTGCCGCTCCGGCAGGGACGCGAGGCCAACGAGCGCCCTTCAACTACCAGCAACCGCCGCACTGCCACCGGCAGTGCACCGCACGGTCGGTGCCCAGCGTCCGCAGCAGGGTGCTCTGGGGTCTCAGCATCACGGTGCGCTCAGCGGCCAGCCTCTCGCCCGTGGTGCAGGCGGGGCTGATGGGGTTGATGCGCCCGCTGGTCATCCTCGCGCACCGGGTGCGGTGCGGGGGCTCCTCCTGGTGGGCGTACAGCTGTCTGAGCGCGCGGCCTCGATCGACCATCTCGGTGACGGAGTCCGTGAAGTGCCGCATCTGCTCGGCGGTGCAGCACCGGACCATCACTGTCTCTCCCACCGCGGTTCCGAACCCGAGAGACCGAACTTGGGTCTGGCCGCTGTGCGACAGGCCGTCGCCGCGTGGAGGCCAGCTCGCCGGGCACGGTGCGGCCGTGGCGCTGGTGGCCCGGCGCGAGACCGTCTGGACAGCACCGCCGCCGAGATCGAGAAGGCTGGCGGCACCGCGACGGTGGTGGAAGCCGACATCACCGACCGCATCCAAGCCGAGGCTGCAGTGGAGCAGACTGTCGAGCGCTTCGGCCGGCTGGACACTCCGGTGAACAATCCCGGCCTGATGCTGCTGGGTCCCGTCGTCGGCGCGGACGCCGAGGAGTGGGAGCGCATGATCGCCGTTAATGTCCAGGGCCTGCTCTACACCACCCGCGTCGCCCTCCCGCACCTGCTCAAGGCCGCGGAGGACGGGCCGCGCCGGGTCGCCGACATCAGCTGTGTCACTGGCCGCGTCGCGATGAACGGCCTCGGCGTCTAAAACCTCACCAAGTTCGGGGTGAACGGCTTCGCCGAGTCCCTGAGCCAGGAAGTCACCCAGCGGCACGTCCGCGTCGGTGTCCTGGAGCCCGGTGGTGTGCACACCGAACTGGCCCTGCACAACAGGCCCGTGATCCAGGACGAGATGATTACTCCTCTCCTCGGGGTGGTCGAGTTCCTCGCCCCCGAGGACATCGCCAACGGCGTCGCGTACAGGGTCACGCGGCCCCGCCACGCCTCCATCGGCGAGCTGTGGATCAGGCCCACCGAACAAGCCTGGTGGCCTCCGGCCCGCCCGATCCTCCCCGGTCGACCGCTCGGCCGGCCGCCGGAACGGGCACGACGCATCATCACCGCACACACCGAATGGACCACGGCACCTGAAAGGCACCCGCCCCGGCCCGACGTCCGCTCGCCCCGGCGGCCTCACCTTCTCAGACCCGGACCGCCATATCTGAGCGCTACCACCACGGGTTGCGCCACGTCCAGGACCAGCTCACCACCTAGCCCCACCGCCCGGTGTGCCAGCCCCTCCACCTGGACAGTGGTCGTAGCCGGCCCGACTCCCGCCTCGGATACCGTGTTCCACTACGGGGTGCCATAACGGATGTGACGCCCCCCACCGGAGGTAGTTACCGTATGAGTTCAAAGCGCAGCAAGAATCCAGCCCTGCCCGTACTTGACGACGCATTCCGACTCGCGTCGGTCAAGGACGCCGAAGAGTCCACCCGGGACTTGGCCGCGCGGCTGGCCACCACCGAGCTGCGCCGCGTTTCCCACCCGGGCCGGGTCACCTGGGAGCCCACCGATCAGGCCGAGCCCGTACCGGTCCCGCCGACTGTGGTCGACGGTGAAGGGGACCTGTGGCTGCGGGACCGGGGCACTGGCACCTGGACCATGCCCGAGTTCAACCCGAAGGAGTTCCCGGCCCGCTGTGGCGAGGTTCTGACGTGGAACCAGCTTGCCCGCGAGTTCGGCCCGCTGACCGCACTCGCCGACGACCGCCGCATCGGCGGCAGGCGGCGCTGACCGCGCAGCCTTCTGGGGTGACCGCGCCCCTGAAGCGCCCGTTATCAGGTAGCTGAGAGCTCCAGCCACCCGCCAAGCTCGACGATCGCGGCGAGCAGGTGAGCGTGAGCCGATGACTCTGCGGGGGGTTGCCGGCAATGGCCGCACGGAGTCCTCCGTGCGGCCATTGCCGTATCCGGGGTCAGGCGGGGGTGATGTTCTCCGCCTGGGGGCCCTTCTGGCCCTGGGTGACGTCGAACGTCACGGCCTGGCCCTCCTGCAGCTCGCGGAAGCCCGAGGAGTTGATCGCGGAATAGTGGGCGAAGACGTCGGGGCCGCCGCCGTCCTGGGCGATGAAGCCAAAGCCCTTCTCCGCGTTGAACCACTTCACAGTTCCCGTAGCCATGTCTCATGCCTTCCAGTCGATGAACGCCTTCCACGACATGCGGAAAGCGGAGGTGATCGCCCTGGTTCCTGCGGCACAGCACAGCAAAACGCCCACGCCGAGGCGTGGGCAAAGGGAACTTCCGAACCACGACAGCTGACGCAGACGGTACACGTCCGCACATGCTGTCACCACAGCAAAGCTGTACACGTCGCGGCTTGGCCAGTTGCGCGCATATCCGCTGAAGGCCGGAAGGCGCTCAGGCTGCGGCCGTCGGATTCGCTGATTCGGCGGCGCGGCGGTATCCGACGTTGAGGTGCTGGGCTTCTTCGAGCTGGTCTTCGAGGATGACGATGCGGCAGGCGGCCTCGACGGGGGTGCCCTGGTCGACGAGTTCCCGGGCGCGGGCGGCGATGCGCAGCTGGTAGCGGGAGTAGCGGCGGTGTCCGCCGGCGGATCGGAGCGGGGTGATGAGGCAGGCCTCTCCGATGGCGCGGAGGAAGCCTTGGGTGGTGCCGAGCATTTCTGCGGCCCGGCCCATGGTGTAGGCGGGGTAGTCGTCGTCATCGAGACGGCCGTACGTGTCGCTGCTGTCATTGCAGCTCTCTGTGGAACGCGTGGAGGGGCCCGGGTGCCGTACTGGCACCCGGGCCCCGAAGGAACTGCTACACCATCTGCCGGCCCTGATGCTGCGCCGGCCTTCTGTTTCCGCCTACCCGACCTGGATGCTGTCGGGGGTGCGGGGATCGCGGATGCGTGACCGGAGACCACCTCACTATCGATGTCCTGCGGTACCCGGGCTCCGTACTGCTCGCCCGGGCGATCCTGATGGCGCTCGGCTCCTCCGTTCTTCCCTCTGGATCAATCACTTACCAAACGGGAACTGCGTACTGCTGATACTGCGAACTGCTGGTACTGCCGCTACTGCGAACCGCTTTGTACTGCTGGTGGCCTCTCACAGCGCCACTTCGGCAGCCAGCCCCGTCGCCCATCCTGCATCTGCTCTGGCTTAGAACCCCACCGCCGAACCTCCCGGTGCGCGCGCCCGCAGCCGACGCCTTCACCGAGGTACCACTCACTGATCTCACTGCTGGGTACTGCCAACTGCACCTACTACGGGTACTGCAACTGCGGTACTGCTCACGGCGGCCCCTGATCACTGCGGGCCACCCGGTCCGGTCACCAGTCCCGTCGCCGTCCTGCAACAACCCTGGCTTCGAAACTCCGTCACCGCACCGTCCTGCGAACTGCAACTGCGTGTACTGCTGCCCGGCAGTTCGTCTCTGCCAGGCCCTGCGGTCCTTCTTGGCTACGGGAGAAACCATAACCACACCACCACCCAATGTCTACTCCGGCCGACACAGATTTCCATGCGCTCGCCGATCAGGTAATCGGCCTCGAACAACGACCCGGACAGGCGCCGTGGGGCCGTCACTGGATTACCCGCCACAGCCCAAGGCGCAAGCACCACGCGGGCTCCAGCGGGCATTGCCGATCCAGCCCGCAGACGCCGCGGATGTGCACCCCCGATCTGAACGGCGGCACCGGGGGTTTCGGCTGGCCCACGGTCAACCGCCTCGCCCGTGCCACGTCGGTCACCCGCTGGCCGTCCGGCGGCAAGACCATACGCGCCGTCCTGCCCCGGTGAGACCCGCCCAGCTTTCCCCCGCATGGCGGCATTGCCGCACTGAGCCGGCGTCGTTGAAACGGGCGTATCCCTCGCGAGGCCGTTCCCGAGCCGGCCCCGCCCCGGTCCTGGTTTCCCCCGAAGCCAGGACCAACTGCCCTCACACACCACCCGCGCAAGCCACCGAACGAACTAGGGTGCGTCTTCGAAAGATCGTTCGTTGGTGGATCATGTTTTCGTGATTCGTCGCCATGAACTGACTGATGTCGAGTGGGAGTTGCTGGCTCCGCTGATACCGAGTGCGGGCAGGGGCCGGCCTCGGGCGGAGGACCGTCGGGTGATCAACGGGATGGTCTACAAGATCCGGACCGGGGTTTCCTGGCGTGACCTGCCGGAACGTTACGGCCCGTGGAAGTCGGTCTACACGCGCTTCCGCCGCTATGCCATCGACGGTGTGTTCACCCGGGCACTGCAGCAGATCCAGGCCCAGGCCGACGCAGCCGGTGACATCGATTGGCTGGTCCAGATCGACTCCACCATTGTCCGCGCCCACCAGCACGCCGCCGCCACCGGCCGAAAAAGGGGGAAGCACCGGACGGACGAACCGGACGATCACGCCCTCGGCCGATCCCGAGGAGGCCTGACTGCCAAAATCCATCTCGCCTGCGACGGCCGCGGTCGGCCCCTGGCCGTCCTGCTGACCCCGGGGCAACGGCATGACGGCGTCTGCGCGAGGCCTCTGCCCGAACGCATCCGAGTACCCCGCACCGGCCCCCGCCGGCCCCGCTGCCGACCGGACCATGTCATAGCAAGATCTACCGCCGCCGCAACACCGTCGAACGCTGCTTCAACCAACTCAAAGGCTTCCGCGGCATCGCCACCCGCTACGAGAAAACCGCCGCCTCCTACGAAGCAGCGGTCACACTCGCATCACTTCTGCTCTGGGCAAGATCAATTTGAAGACGGACCCTAGTGCCGCGTCAGAGAATCTTTGCCCTGTTTGGTCGTCAGGCGGGGCAAGCTCCAGGGCACGGCGGCGCGGCGGGGAAGAGGTTTTCTAACGCGACGCTACTGTTATGAGGGTGGCGGGAATCAATGCCGACCGACGGTGGTCCGAGTCCATGCCGGCGGCCTATGAGCAGTACCTCGTGCCGGTGGTCTTCCAGCCTTTCGCCGGGGACCTGGCTGCCAGGGCGGCGGCACTCCGCCCTCGGCGAATCCTCGAACTGGCTGCAGGGACTGGAGTCTTTACGTCTGCCCTGCTCGTGGCGGCACCGTCCGCCAAGGTGACGGCCACCGACCTGAACGAGGCCATGGTCGCTTTCGGGTCGGCTCGATCACCGGGCGCAGTATGGCGGCAGGCCGACGCGCAGCGGCTGCCGTTCCCGGACGGGGGCTTTGACCTGGTGGCCTGCCAGTTTGGTGTGATGTTCTTTCCTGACCGCATCGGGGCCTTCGCCGAGGTCCGCCGGGTCCTCGCTCCGGGCGGCCGGTTCCTGTTCAACACCTGGGGCTCGCTTGGGGCGCACGCCTTCGAATTCGCGCTGCAGGCCGGGCTGGAGCGGGCCTTTCCGGTCGACCCACCGCAGTTCTTCCGGACGGTTCCGCACGGCTACGCCGACCCCGCTGTCGTGGCCGCTGATCTGGCAGCCGCCGGGTTCGCCGTCGAGGAGGAGCAGGAGCTGACACTTCAGGGCTGGGCCGCGTCGACCGCCGACCTCGCCACCGGATACCTCACCGGAACACCGGTGCGCGCGGCCGTCGAGGAACGCGGCGACGGACCGGCCGTCCGCGCCACCGTCACCGAGGAGATGACGGCCCGGCTGGGCCCGGGGCCGGTCACCGCCCCGATGACGGCGTTTGTCTTCCGCGCCGCGGCCTGAACCGCAGCCCGCGCCCTTGCAAAGGATGGGAGTGAGTCGTTCTCGACGGGGTGCGTCCCACCGAGGCCATGCTCATCAGGCGACGTTGGCCCTGGCCACGACATTGCGTAGCCGTTCATCGGCTGCATGCTTGCATCCGAATGGTGATCCCACGGATCGGCACGGACGATGATGCTCGAACCCTCTGAGCAGCGCCGGACCGCTTGGAACGGCGCGGGAGGGCGACACCGTACCGGTCTCAGTCACCATCGAAGCATCCGGAGCACCACGAATACCCTGCAGTCTCGGGAAGTGATCACATGAGCACTCCGCCCAAGTCCAGACCTGGCTCGCGCCTGCAGGTGCGACAGGTGAGGACTCCACCCAGGTCCGGAACCAGCTCACGCCTGCGGGCGCGACGGGTATCGAGGAGAACCCAGCAGTCACAGACCACCGCGGTATTGATCCTGCCGGTCCTCCTCCTGACGGCGTTCTACCTGGGTCTGTTCGGCTTCGAGGACCTCGACGAGGCCCTGACCTTCGTGGGTCGCATCACGGGCGCCGGCCTCATCGCGGCCTCGGCCATCTCACTCCTGGGCAGCGCCGCGGTCATGGACCACTGGTTCTGGAAGATCTTCCCCTACTCCGGAATGGTTGCGCTGGTCGGAACGGTCGCAGCATTGCTGACCAATGCCATGGTCCTATTCGAGATCTCGAACTCGGACTCTCTGTTCTACAAGACCCTGTTTGGCCTGCTCACGGCGGGCTCCGCATGGACCGTCTTCGCGGTGTGGCGGACATTGAGCAAGATCCCGGCTCCGAAGCGGGTGGCCACGGCAGTCATCGCCTCCTCCGTATTCGCGATCGCCAATTTCGGCTATCAAAACCTCTATCAGCCATCCCAGCACGGCGCCAGGCCTGCCATCAAGTTGACCATGGGGCAGCCCGAATTGAACATGGACGGCAAGTCATTCGCCGTACCGGTCGACATTACGCTCGAAAACCACAGCGAGGTGGGCTTCTACATCATGGGCGCCGAGTTCCACGCCATGGGGCAAAAGGTGAAGGTGATCGAGCATGACCGGCTCCGGCAGAAATGGCGTGATGACGCCCAGAAGTGGAAGGAGTACCAAGAGAGAAGCCCGCTCTCCCGCAGGGAAGAACATCAGGACGGCCAACTGTTGGCGGCGCAGCCCTGGATGGCCCCTGGAGGCTACATCGAGGCGAGCGACTCGGTCGCCATTCGAACGCTCGTGCGACTTCCTATCGACACGCAGTACGACCAAGTGGCCTTTTACGCCACCGCGAGCCTCGCGCGCAAAGATCGACTCGGCCTGGATTCAGTTGCTTTTAAAAGCTACTCCTGGAAGGGTGGCAACGTGCCCCAGTGGGTGAAGAGGCAGAAGGAATTCGACTCCCTCATTTACGTCGGCAGGGTGCATCAAAACAATTCAATCGACGAACGTACGATGGATCCCCGCTCCGTATCCATCTATTGGAAATTCGGCACGCACGGCGCAGAAGTGTCCGCATCCATCACAAAGAAGGGCGACGAAAATCGTGAACCCCGCGAAGCGGAAGTCCGCGCGGTAAGAGACCGATACGGCCTCGTCGATGCCCTGACGGGCCCGATCCAGCGATCACTGTGGGACATCAAGAGCAAGAGCCGTCAATGACCGGCGCACCGGGCGCGCGGGGGCGTGGGGCCGCCAATCCGTCCAGCCACGCCACCAGGGCAAGTGAGCTGTTCATGCGATCCCAGGATTCTGCGTTCCCCACGCCGAGCTGTGCCTCCCTCACTGCCCGGCACAGCACCTCGACGTCGAACATCTCCTCGACCAGCGGATGCCTCGCGGAGCGGCAGAGGTCGATGAGTTCATCGCCGTGTTTCCTCAAGCCGCGGGCGTAGAGCTGGTCGAAGGGCACCTTCACGGCTCGGTCGCGGATCCGGGAGGGGAGCAGATCTTCCATGGCCTCGCGCAGAACGGCCTTCGGACGGCCCGGATGGAACGTGGCTGCAACGGGGAGGCTGCGCATCGTGGCGGTGACCTCCCGGTCGAGGAAGGGGTGCGAGAGGAAGAATCCGTCCTGCCGTGCCCGGTGCCAGGACACGGAGTCGGGAGCGGCAAGGTAATTGGCCGCGTCGAGGAACGACTGTTCCGGCCTGCGTCCGAACACGAAGCGGCTCTCCGCGATACTTGCCTCACGGTAGCCGTGGGCCGCTGCGAATCCCGATCGCAGCCAACGGGGGCGGGCGAAGCTTCCGAGGCCACCCAGCACGGTTCCGCGGTGGACGAGTGCTGTGATTCGCTCCGCTGCCAGCGGGAGGGATGGCCGCATGACGTAGTCGTAGACGACGTCGCGCACGCCGCGCTCGGTTCCCGCGGCCCAGGCGCGTGCCTGCTTCGTCATCTGCCGGAGCTGCCCTGTGCGGGCCAGTTTGTGCAGGTGGAGGGGGTTGGCGTCCACGATCGGGTCGGCCCCGCAGCCGGTCATGAGGATGTCACAGCCGAGTTCCGCCGCGGCGCCGTGGAGCCTGCTCCAGAACGGGGCGCGAAAGGCGTGCGCATGAGGCTCGTCCGCGTCTCCGGCGTGGTGTTCGAAGTCGTCGAAGTCAGCCACGTCGCCGGCGTCCACCATCACCGGGCGGGCTGCAGGTGCATGACGGCGAATCTCCTTCATGGCCTCTTCGAGGTACGACCGCTCCCCGGCCAGCTCCCCTGTGTCGAAGCGCCCGGCCAACAGGGCGAGGTCCTCACCGCGGCCCTGCCCCCTACCCAGCAGGCGTGCTGCGAGCAACGCGATGCTGGTGGAGTCGGTGCCGCCCGAGACATGACATACCGTCATTCGGCCCACTCGCCGCCCGACGGCGCTCTCCAGTGCGAGGCGCAGGTTCTTCCCGGCCCCGCTGAGACGGAGCCCGTCCGCCGTCGATTCCCGCAGGGCGTCGGCTTCACCGACGCGTCCGCGCACCCGACCGCGCATCTGCCCCGTGACCGAAAGTTCCACGACCTCGCCGCCGAGAATCCGGTGCACACCGGAGAACGGGGTGAGTCCCGAATGCGGTTGCGCCAGGTTCCCGGTCAGGTACCGGCAGAAGTAGCCGTGTTCCAGCCTTTCGAAGTCGCCCAGACAGCGCGCCGACGTACTCACCGCGCTCACACGCCCACCGGACTCCCTGAAGAACAGGGGAATGCGCGCATGACAGTCGCGCATCAGCACGATGCGATCGGGGTACACCAGGACAGCCGCGTAGTCGCCGATCGGCAGACGGGGTGTGGCTCCCGGTCGCCCAACTGCGTCCAGGAGCCCGCGTGCGCCCGCCACACGGTCACGGGCCGAGCCGACCCAGCCGACGACCACGGCGGTGCCGGCCCGTGAGGAGACCGTCGTCACCAGTCCGTGCCGCGCCATGGCCTCGGCCGCCCGGAGCCTGGGTGCGCCCCCGGCCCAGTCAAGGCGGAGTGCTTGCATGTCACCGGCCGCCACAACTGATCGAGAGAACCGGCGTGAACCCGTGTCCGCGCGGATCTGCATCAGGGATGCACACGCCCGCCGAGGAGCTCCAGGCATGCAGGGCGAACGGGTGCTCGCGGACACCGACGTGAAGCACGGCATCGAGGCCGCACCGCCGCAGAAGGACGAACGCGGTCACGGCCTCGGCCTTGCAGTCGTCGTTGACGAACCAGCTTCTGCGGCCATGTGTGCGCAGTGCTCGTTTCAGCCGCGCCACCTCCTCCGCTGAAGGGAGGTCTGCACGTGCGCACACCGGGGCCGCCAAGGACAGGAGCCGAAGGACGCGCCCGAACCCGACGGTCCGGATCGAGAGATGCACTCCGCGCAGCCAGAGCCCGACCTCGGCGTCCGAGTACGCCTTTCGGCAAGCCGTCGCGCATCCGGTGCGGATGAGATCGGTGACGAGCTCGGCGCGCTCCTCAGCGCTTCCCACGATGAACTTCTCGACGTCCGTCGCCGTCATGCCGAGAAAACGCGTCCGCCGCCTCCAGTCGGAAATCAGAGCACCGTTGGACATCCCGGTGACACGGCAGTGCGGTGACAGCATCCGCGTCATGGCCTCCAGGGCATCGGTCTCTTCTGTCACCTCACACCCCAAACTCGGCCTGCCGCAGGTACTCTGCAGCAGGCCGAGTTCGACGTGGCGGGCTGTGTCAGGACTGGTACCCGTGACCGTCGTAGAGTTCCCCGCTGAAGCCTCGAATCAAGCGGCCGTTGCCAAACAAAACAAGCCGATGCGGTATACGGCGCCGCAGTCGTCGAAGGTACATCGCCTACCTCCAGAATCAAGCAGCGTTGAACACTTCCGACGCTACTCTGCACCGCATGCCTCGCAACCGGACTGCGGGGCAGGGCCGTGGGGAGCGCAGCCACAGGCGGGGACGGCGCGGCCACGGCGAGGAAACGGGCTCGGTACACCGGGCACCATCTTTCGATGACGGTAGACGTGGACTGCGGCCAGCGGAACACGGTCCGGGGGCGGAGCCGCGGCGACATCCCGCGGGAGCGGCCGGACGGCGCAGCGGATCAACACCCACGGCGCGCGGCTGTTCGGGCGCCCTCATGCAGGATGGCGGTCGTGGCCGCTGCCAGCGCTGCGCCCCTCACCGCACCTCGGCGGCGAGGTCGCGGTGAAGTGTCACGCCGTCGCCGGTAATTCAAGGACCGCGCCGGTCTCCGGGTCCGCGGGGAAGCGCGCGGAGTACCCGTATCGCTCGCACAGCTCCGGATCAGCCCACCGGGCGGTGCGCTGCGTCCGGTAGTTGAACCACAGCGTCGGGCCGTCCGGTGCGGACAATACGACGCGGGCGAGTGCCTCGTCATCGGGATGGTGGTAGGTGTCACCGTTGGTGGATACGAGGTAGTGCCGGGCAGGAGCGACTTCGAGCAGGGCCTCGGTCACGTTCCGCCGGCTGGCGTGGTGGGGAAGTTTGAAGGCGTCCACCTCCAAGGCCCGCAGGCCGCGGTGGTCGGCCACCCCTTTCAGGCCTCCCCCGAGCACGGCGCCGAACGCGTCGGCCCCGAGCACGGCGCGGGCGCCATGGTGCTCGATCAGCAGCGCGATGCTGCTCCCGTTCGGAGCCGTCGTGTCATCGGTCGTCTCGTGGGCGGCGACGGCGGCCAGATCACCGAGGGGCTCCAGGACGTCGGGCCTCATGTCGGCCTGCCAGCCACGCCGGGCATGGTCGATGGTTTCGGACCACTCGCGCTCCAGCATCACCAGGCGCTCGTTGGTCGGTGAGAGCACGGTGATGTGCGGCCCGTCCGGGACCGGCACCTCGATGAACCCGAACTCGTCCCCGGTGTCGATGGGACCGCCGCCGAACGCTCGGTTCCACGGGAGTACGGGGCCGGCGGATACCCCGAGCAACGCCGCCACCAGGCTCTCCCCCTGGGCAACGCTGCCCTCCACCCTGCCCTCTGCGGGCAGGTGCGGGGGGCCGTTGAACCAGTAGTCGCCGACGTCTTCGGCGTACTCGCTCCGCAGGAACGGGAGCATGCCGCCTATGTGGTCGCTGTCGATGTGGGTCACCACCGCGACGTCAATGTGCCGCTCGTCGGGTTCGAGCCGGCTCAGCCTCTTTTCGAGCCGGGGCCAGGTGCCCGGAGGGCCGCCGTCGACGAGCATGCGCCAAGGCGGCCCGCTGCCGCGCGCGCACTCCACGAGCAGACAGTCGCCCAATCGCGCGGGCAGTACCTCGATGCGGATGGCTGTGTCCATGGGATCGTCTCCCTCCAGCCGGGCGCACCACCAAATCTACGCTTGTCAGCCGGGCGCCGCAGCGCTGCGGGGAGGTACCGGCCCGTTCGTCGGCCGCAGGGCAGGCGGGTGAACATTGGGTGATTCGGTGTCCCGCCGGGGCGTGGTCGGGGGATAACGGCGAGGAGGATGAGCAGTCGGCAGGGCTGCCCCGGCTCGCCCAACGCCCACACCCCGGCCGCGCCGCTCCACACCGGAATCCAGAGGATGACCCATGCCGCTAAAAGGTTATGGTGTCCTGGCCGCCCGCGCCGTCGACCGGCGCCGGGAGGGATCCAGAGATACTCCGCACTACCAGATCCACCTCACCGACAACGCCGGCACCCACTACCGGGCCGCCGTCAACGTGGAGTCACAGCAGGCGCCCTCCGAGCTCCTGTACCTGGCCGACGACGATTTCCGCCATCCCGTGACCGAGCTGCTCCCGCCGGCAGGCAGCGGATGGACGGCCCTCGTGTCACAAGCGGGCAAGGCCAGCCTGGACTTCATCCGCGGCAACCTGTTCGACCCCGCCGCGATGCGCATGCTCCCGCCCGATGTCGAGGGCGCCGACAACGACCTGGCCGACCTGCTCGACCACTACGTGCAGCGTGCCATCGCCGACCCGACCGCCGCCGTCTACGTCTTCGGTCAGCGGTTCGGCCCCGAGAAGAACATCCCGGACAAGGTGTTCGGCTTCCGGCCCGGCAACGGCGTACACGACATCCACATGAACCAGGGCAACAGCGGCCGGTTCCACTCCGACAACGGCGTCTGGCAGGACGGCGCCTTGTTCGTGCACCTCCCCGCCGAAAACCGCTGGATCGCGATCTTCCTGGCCTTCCAGTCCCAGGCCTGGCACACCGCCGACCAAACCGGTCACCCCCTCGACACCGCACCGCTCCGCTCCGGCGACCGCGACGAGCCCCTGCGGATCATGGCCGCACTGGTCCATCCCTCCGGCCCCGCGCCCGAAGCCGTCACCGTGCTGAACGTCTCGCCGACGCCGGTCGACCTTCAAGGTTGGCGGCTCACCGACCTCAACCAGCACACCCTGCCGCTCCCCGCCGGCACGCTCCAGCCCGGCGGCACCCTCACCGTCCCAGGCGGCAACGGATTCCATCTCGACAACCAGGGCGGCACCATCACCCTCGTCAACCCGGACGGCATCAAAGTCCACGGCGTCGCCTACACCGCGAGAGAAGGCGCGCGCGAGGGACGGACCATCACGTTCTGAACACCACCCGCACCAGGCCCCACAGCACCCTCGTCGGCCGCCTGACCGGCAGGCGAGGGTGTTCTTGAGTACGGCCATGGGAGTGGATCTGCGGCTGCCGCCGGAATGGGGCGGCATGCCCGGGTACGTATGTGCACATTGGCTTTTGGTGCCACTGGAAGCATGACACCTTGTGGGAGCGGACTGGCCATGCCCGACCACGCACAACTGCGGCGGGCGACCGCCTGGATGAGCGGAACTGCCGTCGAGGAGGGCGACGCCGCCCGCGTCTCGGTTGCCTTGCCCGATTCATCCGGTCACTTCCCGCCGGAGCCTGACATCGCCGATGGCGCCTGCGGACCAGGTTCCACCGCGCTGGAGCCAGGCCGGCTGTACCGCAGGATCAGCGGCCGTGACGATCGGGCTCGGCCCGTCAGGGATGAGGAACTGGCGGAGTTGGGCGACCCGATGGCGGTTACGTTCTTCCGCGCGGGCAGGTTTCCGACCACCGTGCAGGAACTGCTGTCCGAACTCCCCGCCACGGCAGCCGCCTCACGCAAGGTGTACCTGGTCAGTGAGGCCGGGCAAATCTCACCGGGTGCCCTCGGCGAGCGCGACATGCGGTTCGCGATGACCACCGCCGTGGAAGGCAATCAGGTGGACCTTCTGGTCAGCACCCAGGCCGGCGGCGACCCCGAGCGAGGATTTCTCCAGGTCGCGGGGTGGGATTCCGCAGCAAAGGTCTTCAATTTCTATGCCCGTTTCGAATCGAGCTGGGTGTGGGCGGGCAACTCCTGGCACTCGCTGGAGCCCGACTCCCGGGGCAAGGGCTGCTTCGACAGCCATGTCAACGGCAGCGCCGTGATGAAGGAACTGAGGATCCCCTGGCTCAACTGGCAGTCGGAGCGGGCCACGATCCGGCTCGCCGAGGATGACCCTCTCCGCCAAGACCAGCTGTTCCAACAAGTCATCGGAGCCGAGCGGCTGGAACTCACCGTCCGGTTTCTCGTCACCCGGTGGACGGCTGCCCGCCTAGCCGCGGTGACCGCGAACGGCGTGGTGGACCACCCCGACCGGCTGCTGCGCCACCTGTTCACCAACACCACGGTCAACCTCACCAGTACAGACCGGCAGAGCAGCACCATCACTGCGGACAGTGGCGAGCTGACGCTGCCCTCGGGGTTCTGGCTGAACCAGGACCTCCTGTTCGACGACCTTCGACTGTTCACGCAGGCTGCTCCGCCCAGGGCACCGGCCGCCGCGTACCTGGCCGGCCTGACGCGGTTCGGTTTCGGGCTGGAGGAGAAGTTCAGCGGCTTCTCCCAGCCAGGTGACACGTTTTTCGCCTTCGTTGTCCCCGAGGCCGCCCACGAGGACAACGAGGTGGTCCGGCAGATGGTCCGCAAGGGACTCATCTCCGCCAGGTTCGCCGCCTGCGCGCTGATGGTGGACTTTCCCAACCCGGTCTTCAGTCCAGCCCGCAGTCTCCTCATGCGGTACGTGCCGACCACTCCCACCAAGGCCGCGGAGTTGGGTGAAGAGGTCACCCGGGCCATCTTGGACGCCGCGCGCACACGGAACCTGCCCGCCGACAGTCCCGAAGCCCGCTTCGCCGCGCACTGGCAAGTACCCGAAGACGCCTGGCCATCAGTGTTCGGACAACGGGTCGACGCCTATCTGCGCAAGGTCACCCAACGGGTCCAGACCGCATCCGGATTCGACGACTACGTCCGGTTGGCCGAGTCGCGGCGTCGGCAGTTTCGCCGCATGAAACTGCATGAGTTCGAGCTCACCATGCCGGTCACCAACATTCCCCCCGGTGCGCCACCACTGGCGATGCGCGAGGACGGCACCGTCACGGAGCTGACCTGAAGCCGCCCCGCCCCCATCAGCCGGAACGGCATCGGCTTCAGCGGCGCCAGCGACCGCATTGTTCCGCCCTTTCCGCCTTCACCAGCAAGGAGAACGAGCGCCATGGCCACACTCGATGCGTACGGGCCTCCCGGCAACCTCGACGATCTGGATGACTTCGGCCGCAAGGCCTGGAACAAGTTCATCTCCGACACGGTCGACGAGGCCATTCAGGGCCCCGATCCCCGTCAGGTACTGAACGACAGCCCGAGACCGCAGTTCTACAACCTGACCGGCACGGACACGGCCTCGGACGTGCAGCGCGTCTCCATCACGTGGACCTCCTTCCCCCGCATCATCAAGATCACTTCTGTTGGCGATCTCCAGCGATGGCAGCGCGCCGACGCCAGCCGCGACGTCCAGGACGAATACTGCGAGTGGAGCGTCACCCGCGACGGCTCGGGAAAGATCACCCGGGTGACGTTCACCTGTGAAGGCCCCGAGTATTGGGAAGTCCTGGCCCACACGAACCCGGACAAGGTGGTCGACCTCTACCGCGCCTTCATCAGTCCGGACGTGCGGAAGGAGGATCTGTTCTCGCCCAGCGGCAGGTACCAGCCGCGCAACAAGTGGAACGACTCCACGAGCCACGGCGCCATGCACCTGATTCAGGCGAACAACACTCTGGGCGCGGAGATCGAGCTGGCTGCCGCAGCCACCATCCGACGCGTCGTCAACGGCCAGGAGTTGAGCACGGAGCAGGAGCTCGTCAATTGCAGCAAGTACGGGGCCGCGGAGCGCAACAGTGATCCCCACATCGGCGCGGGAGTCAACGCCCTGGCCCGTCAGAGGGCCGACATCAGCCTCGCGGACCCGGTGGGACTGTACTTCGACGACCTGTCGACGGACGGCTGGGAGACCCCGGACGGCTCCGATCCCCGGAGCTACTGGACCTATGTGAGGGGCGACTCGGAACACCGTGTCCGCGCCGTCTACGAAGTGCCCCAGGACAAGGGTTTCGCCGTCGGGGACATCACCATCGGCGGGAGGCCGATCGAGTTCGGAGCCCAGATCGCGGACTTCATCACCATCAGGCTCACGGGCCTCGCCTGCCGGTTCGACGGTTCCACCGCCCAGCCGCAGACCGCCTGCAAGGAGTTCCCCGCCGTCGACGTGCGGCCGGAGGGGTTCGGCGCCTCCGCGTTCTCCACCTCCGGCCGCTTCTTGGATCCCCGGCCCACCCTCTCCTACCGCTCCTCCCGCGCCACCTGACCCGTTCCGCCGGGGAGCGGCCGGCGGGCCCGAACCCTGGACGGGATCTCGCCCGTCACCCGGCAGAAATCGCTTCCTTGGCCTGGGTGCCGATGTAGTGTCCAAGCTCCCGGTAGGCGTCGAACTGGGCATGGTCGAACCACTGGTCAAAGGTGGCCTGGCGGGGGAAGGCCTTCTCCCTGAGGGCGTAACTGAGCAGCTCGTACGGCATCTCGCGGGTCAGACTGGCCTTCACGAAGACGATCGTCCCCTTCGTGTCGGCGGGCGTGCCGGGCGAGAACTCGACCGGCTCGGGGTACTCGATCGTGCCGCGCACCACGCAGCTGGCGGAGAACCGGGCGTTCAGCGCGGCCATCGGCGTCTCGGGCGGAAGCGGTCTGGCGCTGCCGGGTACCAGGTCCAGCAGGTTCTGCCCCTCCTCCTCGAAAGTGATCTTCACTCCGAGGTCTTCGTAGGCGAGCGTGACCGCCTGCGCGAGGGTGGTGGCCAGCGGTGGCGTGTCCCCCGAGGAGTCGATGACGTAGATCGTCCGGCAGCGGAGCCGGAGCGTTTCGACCAGACCGAGATTGTCGAAGTGCCCGCCGTCCGTGCACAGGAGCAAGGGAGTGGTGTCCGAGTACCAGCCCACCAGTTCCTGGAGCTGGTAGCGCAGCCGGCGTACCCGTGGCAGTCGCGGCATGATCCGGCAGGGCCCGTACTTCGCCAGTTCCGCGAGGTAGAGCGGGTTGGGGACCCAGGTGCCCAGCCGCACGTTGGAAAGGGCGAGCAGCCGCTCCATGAACATCGTCTGAGTGCCCATCGCGGAGGCGAAGGCCGCTCCTGACACGGCGATGGCCGACTGCACGGTCAGATCGCGTCCGATCAGCGCGGGGGCCGTGTTCTGCAGGGTGTCGGTGCGGACCCAGCCCGTGTCGGGGCCGCCGCAGTAGTCGGAGGCGAAGGTGAAGGGCACGGCGGGGCGCCCGGGGGCGGTGCGGTTGCGCAGCGAAATCGCGGCCGAGGCGGCGAAGACGACCTGGGGGAAGCCCGCCACTCGCTGCGCGTAGGGGTGCAGCGGGGTCGGCTCGTGGTTGTAGTCGTACGGCAGGGCGCCCACCGAGCCGTCCTTCAACACCGCGCGCCGGACGGCGAAGGCACCCGCGAGCCGCTGTCGGTAGAAGGGGTGCAGGCTGAAGGTGGTCTGGTCGATCACGAACGCCAGCACGATCAGGGCGATGGGGATTCCGGCCTTCCACCAGATGTCCCAGCTGTCGGCGTACACGGCGGCCCAGGACATGAGGGCGAGGTAGAAGAACGCGACCAGGAGCAGCACCAGCCAGCACACCACGACCTTCATCCAGCCGGTGCCGACCTGAACGACGAGGGACGGCCCGCTCTTGCCGAACAAGCCGGCCTTTTCCCCGTCCGGCCTCACCTCCTTCACGGTCTTGTGGACGACGGTGAACCAGGTACCGACCGCAGTCGCCACCGCCGTGAGCGCGGCGAGCGCCGACAGTCCGCTGCCGTCGTTCTGCACCACCCCCTGTTCGAGCGCCAGCCAGGCGAAGAACCAGATCACCGCCGGAAGGACGACGGCGATGAGGGCGACCACCAGGGCCATGGCCACGATCGTGTTCACGATGCTGCGCAGCCAGGCGGGGCGGGACTTCATCGTCCCCGCCCCGACGAAGGCGGCCCCCACGGACACCAGGCCCGCCAGGCCGAACAGGGCGAGAACCGGGTGCCAGGCGTTCGGATACCACTCAAGGGACGGCAGGAACATCTGGGTGGACCCGGGACACTTCGGGACGTCCGGAACCTCACACGTCGGCGCGAACGCCTTCGCCTGCGGCATGAAGCGGCGCAGGTCGGTCAGCGGAAGGTGAGAGTAGAACACGTTCAGGAACTGGCCCGCCACGGCGAAGAGCAGCGCCAGCATGCCGAAGGAAACGGCCATGCCCCGCAGCACCGCCCCCACGGCGTGCATCCTCTCCTTGGGCGTGTCGGCCAGGTACTTGGCGTGGCGGCGGATGTGGTCCTCCTCCTGGCTGCCCGGCAAGAACGCGTCGGCGGGCTCCGCAAGACCGGGCCGCACCGAAGGGTTCCCGTCCGCGTCCCTGAGTCGGGCACCGGTCAGGGCCAGCTGAAGGGCGCCGGCCGTGTACCCACCGCCGGACACCGCCACCAGATAGTCCGCCTGGAGTAGCTGCCCGCGCAGCGCCTGGAGCGCGCCCAGGGTGATCGAGGCCGACCGGATACCGCCGCCGGAAACGCAGAAGCCAACCTCGGCAGGCTGTCGACCGGGCGGCTGGTAGGCACGCGTGCGCCAGCGGGTGGCCGTCTTGTCGGCGGGGTCCTGCGCCTGGGCCTGGTGCGGTTTTGCCGGGTCCGGGGCGGTCCACTCGGGTCGGGGCTCCCAGTCGTGGGGCGCGGCGGGCGGAAGGATCACGTCGGGGTGGCTGCGCTGGCTCTCCGTCTCGCCGGCGGGCCGATTGGTGTGGGCCACGACGGGGCGGGGATGGTCCTCCCGGCCGCTCTGCAGGAGGGAGGGGTCCTGCACACGGCGGCAGTAGAGGGTGACGACGACCACCGCGGCCGCCGCCACCAGCGGGATGACGAGTGCCCACTTCACCTGGGCGAAGTAGGTCGCCCACTGCAGATTCCGCTCCAGATCACGCTCCGAGGCCGTCGGCAGGACGCCGGCCCAGGGCAGTACGGGACCGTCCGGGTCGGCCTTGATCCGGTCCAGCGCCTTCCAGAGGAAGATGTTCTCCACGCAGTCCGCCGCCACCACCACAGGGGTGAGAAAGAGCGCGCGCCGGGCCCACAGGCGCGTGGACTTCCGGTAGAGGAACAGGTACCCGAGTCCGAAAGCCCCGGCGAGAGCCGCTCCGTACCCGGGAATGAACCAGCGCCAGTCCAGCACCAGGCCGTCCTGGAAGAGCTTGGACCCGCCTGCCTCCTTCACGATGGCGCGGGCCGTATCCGCGTTCGTCGGGAACTGCAGCAGCAGTTCGCCATCCTGCGAGGGTCTGGCGCGGAAGGGTGGATCCGCCGCATACCAGAGGATCATGAAGAGCCCGGCGGCAAGCCCGAACAGGCACAACCACACTGCCCAGCCCGGCACGTCTCGCAGCTTCACCCTCGCCTGAGCATTCGCCATGCAGGCAAAGTAGTCACCTGAACACGATTCGTAATGATGCGCGCCCTACACGAGGCTGCGCAGGACCCACTCAGCGCACCCGCCTTGGCCGCGGACCCACCGTTCCCAGCCTGAAGTGTGCCTATATGGCGATCACGTCACTGGATGCAGCGTGTTCCAGGGGGTGAAGGCGTTGTCCACGGCCCGCATGGGCGAGCGCAGTTCCGGAAAATGGCGCAGCATCACGCTGGTCATGCCGTTGTTCTCGATCCAGTCCAGGCCGGCCTGCGTGTACACCTGTGGTGTGTAGTCCCTCGTCAGGAACCGGTCGCTGTTGAGCCGGCGCGAGGCCATCAGGACGAAGATCCGGAAGGCCGTGTCGCTGAAGGCGAAGCCCTTGGGCCGGGGCTCTGCGTACATTCCCACCATCAGGTCGACACCTTCGATGTCGTCGTCGTAGATCCGGCGCATCTCCTCGGCCCAGACCGGGTTGTCCGTCAGTGTGGCGAAGTCGGCAGCGGGCTCCAGGTGGAGCCGGCGCCGGAACTCGTTGTACCTGGGCACGCCCATCTCGCGGATCCGCAGCACGTCGACGGCCGCCAGGTCCATGAGTTTCTCGTCCGGACGCTGGTACTCCTGGAGGAACTTCGGGTAGTTGTGCAAGGTCACCAGGCCGGGGTGCGAGGTACCGAAGGAGTAGAACAGGTCCGGCAGGCCGTGGTTGGCGAACACCTCGTACGCGCGCCGGCCGGTCAGCTCCCTGAAATTGGTCTCCTGAAGCAGCGAGTCGTCCGCGGCCGAGCGGAAGCTCCAGTCGTCGGGCACCAGCGGATGCATGCGGTAGACCGCCACGAACTCTTCGGTGAGGGAGTAAGGGACGCCGAAGTGCTCGGTGTTGCCGCCCACGATGCCGCTGAGCAGCTCGTTCCCGCTGATCCGGCCGAGTAGCCGTTGCACTCGTTCGCCGAGCAGGCCGTACCAGTTGGCGCGCAGTGCGGTGACGGTCGTCGGGTGGCTGATGACGGCGGGGGTCCACTCCACGGTGTGGATCTTGGCGATGAGCGCGGCGTTGATCAGGCGCGCCCGCTGAAAGAACTGTTCGTCCGACCAGGCGGGGAACTCACGGCTCAGCCGGTCGCAGATGGCGTTGTGCTCCAGGGCGAACACGTGGTGCATCATCAGCAGGCCCAGCCAGAAACCCGGAGTGTTCGCGGGATCCAGCTCCGGGGCGTCCGCGAACAGCATGCCGTCGCGGGGCGCTTTGAGTTTGCCCTTCTCGCCCGAGCGCATCCGCCGTTGGGTCGCGAGGTCGCTCCCGTAGAGCTGGGAGGCGTCCCACCAGTGCGAGTTCTCGTTGATGTACGTCGGCGGCAGGCCGTCCCCGTCTTCGGTGCGGGTGGTGTCAGGCAGGGTCCGGGGTACGAGCATCGGCTGGGTCGGCCAGGGGTCGCCGTCCTCCAGTTCGATCCGCCAGGGGTCGTCGATGGCACCCTGTCCGTGGCTGACCCAGTCGCGGATCATGAACTGGAGCCATGCGGCGACCAGGGCGTTGACGGACGTGGCCGGGATGAACTCGTCCCGGGTGAGGAGCGTACGGCTGACCTCACGCGGGCTCGGAGTGAGAATCTGCGGCTCCGGCTCGGGAAAGGTCACGTCCGGCGGGACGTTGCGGCCGAAGCGGGAGTGCGCCATGCCCATGCGCGGGTTGTCGAGGTCGTTGTAGGAGCCGTCGGCGGTGCGCTCGGTGAGGTGCCGCGCGGCCGGCGGCTCGATGTCGGGCACTCCCTGTGCGGGGTACCCGTTGGTGTCGTGCAGGTTCTTGCGGCGCAGGTTGTCGCGCAGGCCCATGAGGGTCAGCAGGCCGAGCGGCGTCGGCAGATGCTGCCAGCCGAGTTTGCGGTCGACGGCCAGCGCCACGTTGTCGTGCAGGCGTACGAACGGCGAGCAGGCGCCCTTGCCCTCGGCATGAGCCGAGGGGTGCGTGCGGGTCCGGGCATGGAAGGGGGCTTTTCGCATCGCGGAGTTCCTTTCGGCGCCACTCGGTCGAAGGGGTCAACCCGTGCCCCGCCGCGGCCAATCGGCCACCAGCGTGAGGGCGACGTTCACAGTGGAGATCGCCGTCGCGGTCGCCGCCGCCCGCGGCGCGAGCATGCCGCACCGGCCGGCTGCGGCGGCCGACAATGCGTCGCTGGTGTGGATGACCGTGCCGACGTGCAAGGCCCTGGCGATCCGGGCAGGGTCCTGGAGAAACAACAGTTCGGCGCCGATGAACGCGGTCCGCACACCGAACATCCGCAGGACGTGGGAGAGGGCCGGCTGCATACCGTCCGCCCCCAGCCGGCGGGCCACCACCTGCGGGGCCAGGAGCGCCGCCACACCGTTCACCAGCCGGATTCCGGCCAGGCTGTACCGCGCAAAGGAGCGCGCGTTCATGGCCATTACCCCTTCCAAGGAGATATAGGGGGAATAGACGGTGTGGGAGCTCGGGCGTCCTATACGATCATAGTGGGGATCGTATGTCTTCGCGCGCCGTGCGGCAGTCGTGCCGGGATCCGTGTGCCCGGGGGGTCCACGTCAGCCCTCGCAGAGGTAGCGCAGCGCCTGGAGGCCCGGCAGGAAGAAGTAGGCGCCGCCCCGGATGGAGACGAACTGCGGCAGGCCGCGGTAGCGGGTGCGGACGGGCACCGCTTGGACGGTGAACGTCGCATCATGGTTCTGGCGGGGCGCGACGACCGGGTCCGGACCGTCGTACAGCCCGTTGAAGTGGGCATTGTTCAGCCAGGTGTGCTGGACGAACTCGAACTGGCGGGAGATGTTCGCTCCCAAACACAGGAAGTGCAAGCCCGTCTCCCCGTCGCCGTCGGCCTCGCCGTCGCCGCCGTAGGCACGGCCGCGGCGCAGGAGCCGGTGGCGTCGGCCGATCGCGACCGACTGCGGCGAGCCGGGCTCGGGGTCCAGCGAGTCGCGGGGGTTGGCCCGGCGCACGTGGGCGCCGAGGGGGCACCTCAGGCCGTCCGGATCGGTGGCGAAGTAGCCGAAGTCGTTGTCCGAGCCGAGGCTGGGGTCGTCCCGCAACGGTGCGTGTACCAGTGGCGCGCCGCTGGGCCAGCGGCCCACCATACGTGCCCCGAGCGCCTCGCCGGCTTCGGGATCGGCGGAGCCGTCGGGGCGCCGCGTCGCCTCTTCGAGGTACCGGTGGAAGCCCGCCACGTTCTGACGGAGCTGCCGGAACACCAGGTAGCTTCCGTTGCGGCCGAAATCGGCGGCGCTGCCTGCGTCCGGCGCGCGGGGCAGCAGACCGGTGGTGTCGTACCCAGCGGGCAGCAGCGGCCGGTCGGTGAGCAGACCGTACTCGTTGGCGTAGCCGAGAACGAACTCCCCCGCCTTGACCGCGTCGTCGCCGACGGCGACCTTGGAGAGCCCCTCGACCAGGGGCTGGGAGATGCCGTCGCGGAAGCCGAAGGGTTCACGGTCGGTCAGCGGGGACGTGCCCAGACGGGCGGCCACGGTGAGCCAGCCGCCCCCGAGGGCGTCCTGGCGAACCTGCGCCTCCAGCCGGCCCAGGAGCTCTTCGTCCCGGGCGTACAACAGTGCCAGGGCGTCCACGGGCGGGCAGTCCGGACCACCCCAGTGCCAGCCGTTCGGCGCGTTCTCCCCCACGTCACCCAGCAGACGGGAGCGACTGGGGTCGGTCATGCCGGAGACGAACTCCTGTGAGAATCCGTCGAGTTCGCGGGTGTCCAGTCCGAGGCGGCGCAGACCGTCCGAGGTGAAGGCCAGGTTCAGGGCCGACTCGGGCGACTGTGCGCCGCCGTTCGTCACCAGCCGGGCCAGCCGCCCCAGTGCGGGGCGCGCGGCCGTCGGGTCCTCCACCGTGATCAGCAGGAAACAGGCCGACTTCAGGTCGTTGTAGCCGCGTATGACGAGGCCCTGGATGTCGTCCAGCTCCAAGGGCGCAGCAGTCTCCGCCATCACCGTCACACCCCTTCTCTAGAACAAGGCGAGCCAGGCCCTGGTCTCGGCCGGGCCGAGTTCCGCGAAGAGGCCCGCGCGGATGGAGGCGTTGGTTTCGAGGTTCCGGGTGGTCAGCGCGTCATACGCGGAGTACCACACCTGCGTCGGCAACTGGTGGCAGCGCAGGTAGTGCTTGAAGGCCAGTTCGTCCTCGGCGCCGTCCCACAGGAGCCACCTGGTGCGCGGATAGCCGTGGCCGTTGCTGAAGACGGCGTTGAGGCCCCAGGCGACCTTGTCGATGAAGTCGTCCATGTAGCTTTCGAGGCTGCCGTCGTAGTTGCTCGCGAAAATGACGCGCCGTTTGTCGTCCAGGAACAGCCAGCGGGCGAAGTGGATGGTCTTGACCCCGGCCAGGCTGCCCCGGTTGAAGAAGTGGCGCACGCCGTAGTCGACGGCGAACAGCACCCCGGTCAGCGTGGCCCGCCGGAACCGACCGGACTTGACGAGGCCCACCGCCGTGAACGGATTCTGCGTGGCGAAGTCCTCGCAGGCCGCCAGCCTGGCCACGTGGTCACGTGAGGGGTGCTCCTGGCTGGGGACGTCACCCCGCTCGCGCCAGCGCAGCACCACGGCCCAGACCGGCAGTGCGATCAGGATGACGGGCAGCAGCGCGAGCGCGATCAGCGGTACGCCCGCGAGGTGCACCGCCTCCCGGATCTGCCACCGCAGCGCGGGCGGGGTGGGGCCTGACCGCGCCCAGGCCAGGTCGGGGCGACCGGCGACGTACCGCTGGATGGCGGCCCGTACCTCCGCCGGATCCGCGGTGGCCTGCTCGGCGCCGCGCCGGTCCAGGAACTCCTGGATCGCCTCGCGCAGCCGGGCTTCCTGCTGGATCTGGTGCAGGCTCCGGCCGACCGTATTGACGTAGAAGGCGTCGCTGGACACGCAGTGGGCCCGCAGCCACGCAACCCGCGCGGCATCCGGTGCGCCGTCGGGTGGATAGTTGCGGCAGTGCCCGAACACCTTTCCCAGGCCGCTGCCTGCCTTGGCGACGAGGTCGGCGAGGTGCGCGTCCAGCGGTGCGTCGGCCTCGCTCATGTAGACGATGCTCGCCGGCATCGTCTGCCCGGTGTGGTCCGTCTCCTCGGGAACGAGGACCAGTCGCGCGAAGTGGACGCCCGCCATCTCGGCGAAGTGGATGAACTCGCCTCCGGCGTGGCGGCGGTTGGCCTCGGCCAATACCTCTTGCACTTCGGCCACCCGGTCCGGGGGCACGGTGGCCCGGACGGTGACGGCGATCTGCTGCGACGCGCGTCGAGACGAAGCTGATGCGGGCGAACCAGGAGAGGACAGGGCGAAATTGAGGATCTTGCGCCGCCCCCAATAGACGATGCCGAGATGGACGCCGGGCGCGACCTCCCGGATCTCGTCGCGGATCCAATGCGCGAGGGCGGACGTCCGGGAGTAGTCCAGCACGGTGCACTCCCCGCCGTCGAGCCGGCTGGCGCCGCGATACACCTTTGCCCGTATCGCGCGCACTCCGAACGGCGTGACTTTGTTGCGCAGTTCGCCCCGGTCGGCGTCGAACACCTTGCCCTTCCACGCGATGAGCCGCACCAGCCGGGCCACCACCGTCGACAGCGCCGCCCCACGCGCCACCAGCACGGTGCCGCGTTCATCCCCGACGGGTACCTCTCCTGGGGGGCTCGTACGGAACAACTCATCGAGAGCGGGGCGGGAAAGGGTTATCAGCCGAGCGACATCCGCCCCCTTGGCACGGCTCATCGCACACCTCCGTGTGCCATACCACCAGGGTGTTTCACCAGGCGTTACTGCTGCTCCAGGTATTCCTGCAGCCGTGCGAGCAACGCCGCGAACGCGGGGGTCATGGCGGCGTCCGACTGCTTGAGGACCGTCGATCGGCCGCCGTCCTCCACCGTTATGGTGTAGCTCATCGCGTCCCTGGCCCGGCTGGGCTGGTCCGCCACGGGCGATACGACGGCCGCCGCCACCAGCCGGGCCAGCTCCGAAGCGGCGTTCTCCGCCAGGGTGTCCGTATCCAGCACCTTGGGCGGGAGGCGGAGATTGACCGTCGCCGCCAGCCCGCCGTGTGTCGCCAGAGTCACCTTCATTGCGCGCACCCTCGTATCGGCGGCAATTCCTGGTGTCAGCCGGTCCCCTTCAACGCGGCCACGTCCTTGGCCAGTCTCGTCATCTGGGCGCTCAGTTCCCCGACCTGCCTGGTCAGGGCTGCGACGCCGTCCTGTCGGCTCAGGCCACCGTTCCCGTCGACGGTCCGGCTCCGCCCCCGGGCGACTCCGGCCGGGACGCCGCTGATGGGGATTTCCACCCCTTGCCACGCCGCCAGCACGGCCGACTGCTCGGCGCTGCCGACACCGAAGAGTTCCCCGGCCTTCTGGAACGTGGTGTCCGCGAAGTCCTGGAACTGGGTCTCGGAGCTGGACGCCTTCAGCGATTCGTACCAGATGGGCCCGGCACCCTCCCATGCGAATCCGCCGATGCCAACGGCCGCCAGGAAGAACGCCTTGTTCGGGATGCCCGAGTTGAAGTGCACCCCGCCGGAGTCCCCTTCCTCGGTGTCGGGAAGGTGAATGAACTTACTCATGCGGTCAGGCTGAGGGTCCTTTCCGAACAGTGCGTTGTCGTACGCGTGTCCCGGGGCCTTCATCGAACGCAGGGCGTCGGCATCGATCCCCGGAGTCCACACGTCGGCCCCTATCAGCCAGTCCGCCTCGTCGACCGACTGCTTCAGCGACCACTGCTTCACCAGCGACCCGAAAACATCCGACATCGACTCGTTCAGGGCCCCGGACTGGTTGTGGTACACGAGTCCGGCGGTGTGTTCGGTGACTCCGTGCGTCAACTCGTGCGCAATCACGTCGAGGGATCTGGTGAGGTCACCCAGCATCTTTCCGTCGCCGTCGCCGAAGACCATCTGGCGGCCGTCCCAGAACGCATTGTTGAACTTCACACTGAAGTGAACGTACCCGTCCAGGCGCATTCCGTGGCCGTCGATCGAGTCGCGCTGGAACACCTCCTTGTAGAAATCGCGTGTCAGGCCGAGTCCGCCGAACGCCCGGTTCGCGGACTCGTCCGCGGACTCCGGTCCGTCCTCGGACCTGGCCATGACAGCGGATGCGAGGAAGCTCCCTTGGTCGCAGTCGAAGACGGTGCGCCGACCGTTGCCGGTGGCGGTTGCGGCCGGGCCGGCGAAGGACGCCCGGACCGCTCGTTCGCCCCGCAGGCGAGCGGTGGTCAGCATGGTGTCCAAGGCGGCCTGGCGCACGTCGCTGTCCTGGCTCTCCAGAAGCCTCTTCAGAAGGTGCGGGGGGATGATGCAGTTGAGTCGGGAGGTCTTGCTCATGGGACACCTCCTGGGAAGGAAAAGCAACGGGCAAGCAGGCACCGGGGCGGGGAGGGTTTGCGGCGTTCGATGCGGCAGCACACAGCCTTGCCGCGCCTCTTGGAGAGGGTCTCGTGGACGAACTGCAAGATGGAGTGCAGGAGCCCACTGGGCGCGGCAACAGTGGAAGAAGCATCGGCGCCGGCCAGCCCGGTTTCCAGAGGCGGGGCCATGCTCATATCACCAGTCTCCGGCGCCCCCTGGCGACTGGCAAACGCAACCCGAGCGCACATGGGATGAACCCGGGCTCAGAGCCCCGGGGCGGGCCCCGGACGCGCGGGTGCCGCGGTTGCCTGCGGAAACGCGGCACCCGCCCGGCGGCACGGGCCGCCGGTCGTCAGCTCAGGAGCCGTCGCCCGGGGGCGGGTCCGTGCACGCGTACTGCGCGTCGATCTCCTGCGCCGTCCTGGGTCCCTTCCGGGTCCAGTACGTACCCGCGGGCAGCTGCGCCGCGGCCACCTCGGCGGTGTCTAAGACCTCGCCCCGTCCTCCGCGTTCGGCGCCCGCCACGGAGACCGCGGGCAGCTTCGGCCGCACGGCGGGCTGCTGCCCCCCGGTGGCCCTCCCGAACTGCTCCGGCCTCCTGCGCGTGACGTCGCCACGCACGCCCTCGGGCGTGAGCGGGCCGGTCGCCTGCCACAGCAGCTCCTCGGTCTGCGAGTCGTGCACCCGCACCTCGTCGGCCTTCATGTACGGGCACAGCGGCCCCTTGACTGTGAAGCTTCCCCTTGATCATGGGCACCTGGAGACTTGGACATTAGGCTCCAGAGGAAGTAGCACCCGGTGGTAAGCAAGTACACGAAGCGGTACTCGGTGGAGTACAAGCGGGACGCGATCGCGCTCGTCCACTCCTCCGGCAGGACTGTGACCGAGGTCGCCCGGGAGCTCGTGATCAGTTCGGAGTCCCTGCGGGGCTGGGTGAAGAAGGACCGTGCCGCCCAGGCGACGGCAGCTGGGTCGGTGCGGCCGGGGCAGCGGGGCGACGATCGGGACGAAGAGCTGAAGCGGCTGCGCAAGCTGACGGCCGAGCAGGCCAAGGCGATCGAGATCCTGAAAAAAGCGACGGCCCTCTTCGCGAAGGAGAGCGACCGGTGAGCACGATATGCCGGTTCATTCACGTGGAGAAGGCAAACTGCCCCGTCACGCTGCTGTGCAAGGCCATGAAGACTGCCCGGTCCACGTACTACGCCTGGGCGGCCGGCATCGAGGCCCGCGAGGCCAGGCGGCGGGCCGATAAGGCCCTGGCCCACGCGATCACGGTGATCCACCTCGCGTCCCGGCAGAACTACGGCGTCCCCCGCATCACGGCTGAACTGCGACGGCAGGGCCGGAGGGGCAACCACGAGCGCGTCGCGCGGATCATGCGCGAGCACGGCATCGCCGGAAACAGCCGACGCACCGGGCGCCGCAGCCTCACCAAGGCCGACAGCAAGGCAGCCCCATCGCCGGACCTGATCGGCCGGGACTTCACCGCTGCCCGCCCCGGCGCGAAGATCGTCGGGAACATCACCTACATCCCCACCGCCGGGGGCCGGCTCTACCTCGCCTCATGGCTGGACCTGGCCACCCGCGAAGTGATCGGCTACTCGATGGCCGACCACCACCGCGCTGACCTCGTCGTCGATGTCCTGGACATGGCCACCGCGCTGGGACGGCTGGAGCCCGGCTGCGTGATCCACAGCGATCGCGGCTCGGAAGGTGGATTCAACCGGCCGTCGCAACACCCTGACCTCGGAGGTGTGCGACGTGGCCACGGCGGACTGGAGTTTGAAGACCAGCGATGTTCCGGAGGGGCGGCGTCGGCAGTGGCGCGCTAGGTGTATTGACCCGCAGGGTTGTTTACGCGGCTGATGGGCGGGTGTCCGCCCAGGGCGGTGTGGCAGCGGTGGTGGTTGTAGGTGTGGAGGAAGTCTGCCAGGGCTGCTGTCCGCTCGTCGTTTGAGGTGTAGGGCCGCAGGTAGGCCCATTCGTCGAGCAGGGTGCGGTTGAAGCGTTCGACTTTGCCGTTGGTCTGGGGCCGGTAGGCGCGGGTGAGTTTGCCGCTCGCGCCGAGGTGGGCCAGGACGGTCTTCCAGGCCAGGCCCTTGCGGTAGGCCCAGGCGTTGTCGGTCAGGACCCGTTCGATGCGGGTGATGCCGTGGTGGTGGAAGAACGCGGCCGCGCGGGTGAGGAACCCCGCGCAGGTCGCGACCTTCTCGTCGGGGTGGATCTCGCTGTAGGCCAGGCGGGAGTGGTCGTCGACCGCGGAATGGACGTAGTCGAAGCCCATCCCGTTGCGGGTGGCACGGCCGGCCTGCCGGCCCAGGGCCTTGTGGCCGCCGCCGTCGGGGATCCGGCCGAGCTTCTTCACATCGACATGGATCAGCTCGCCGGGCTTCTCGCGTTCGTAGCGGCGGATCAGGGTGCCGGTGGGACGGTCCATGAACGAGAGCCGGTTCAGACCGTGCCGGGTCAGGATTCGGTGGACGGTCGAGGCGGGCAGGCCAAGGACCGGGCCGATCCGGGCGGGGCCCAGCTTGCGGGCCCGCCGCAGGTCGCAGACCCTCGCTTCGACCTCGGCCGAGGTCCGGTGCGGGGTCGTGCGAGGTCGGCTGGAGCGGTCGTGCAACCCGGCCGGGCCGTTGTCCCGCCACCGGCGCACCCACTTGTGTGCGGTGGCCCGAGATATGCCCATCTCGGCGGCCACGTGCGCGACCGGGCGGCCCGAAGCGACCCGCTCGACCAGCAGGCGCCTACCGAAGACGGTCAGCCGGGCATTACGGTGGGACACGAAGACCTCCGTTGTGCAATGGGTTCCTAGACAGCTCCCACCACACCGGAGGTCTTCGTCATGTTCAAGACCCACCGAGTGTCAACAACGCTCGTGATCAATACAGCTAGGCAGTGTCTGATGGCTCCTGCCCGGGTGGTGGATCTACCGCTGTTCTGGGCAAGAAGTCGTCATGGCGCGCTCGGCATGAACTGACGAATGCTCAGTGGGATCGCATAGCCCCGTTGCTGCCGGAGACCGGTAGCCCGGGTGGTCGGTGGGCCGATCACCGGACGGTGGTCAACAGGGTGTTCTACCGGACTCGGACGGGGATTCCCTGGCGTGACCTGCCCGAACGTTACGGATCCTGGCAGACCGTTTACGAACGTCACCGCCGCTGGTCGGCCGACGGCACCTGGTCGAGGATCCTGCGGGCGTTGCAGGCCGACGCCGATGCCACCGCCCCGGACGCGGACGGCTCGTGGGCGGTGAACGTCGACTCCACCACCTGCCGGGCCCATCAGCACGCGGCCGGAGCCCGGCACGCACCCCCGGCCGACCACCCCGAAAAGGCGCCTCTATGGCTTTCGTCAAGCTGTTAG

Protein sequences of DBSCAN-SWA_2

>NZ_CP024985|209435:263667|220278_220752_+|WP_158741016.1|DBSCAN-SWA
MPWSTAKNGNPFNVPRMVLYRLGDAIDTLSQITRVVTQVYRENGRAEHDLNSYRQPLQERSRTDSLDDSDHHYLAGLLGRPLPADNGSATGLYDWGRSEAEHPDLPEVVNTRACLYALRASGSEEPETVFASLNEPTRAVARAVAQHLLPPCDDDLP
>NZ_CP024985|209435:263667|255512_256910_-|WP_030241070.1|DBSCAN-SWA
MAETAAPLELDDIQGLVIRGYNDLKSACFLLITVEDPTAARPALGRLARLVTNGGAQSPESALNLAFTSDGLRRLGLDTRELDGFSQEFVSGMTDPSRSRLLGDVGENAPNGWHWGGPDCPPVDALALLYARDEELLGRLEAQVRQDALGGGWLTVAARLGTSPLTDREPFGFRDGISQPLVEGLSKVAVGDDAVKAGEFVLGYANEYGLLTDRPLLPAGYDTTGLLPRAPDAGSAADFGRNGSYLVFRQLRQNVAGFHRYLEEATRRPDGSADPEAGEALGARMVGRWPSGAPLVHAPLRDDPSLGSDNDFGYFATDPDGLRCPLGAHVRRANPRDSLDPEPGSPQSVAIGRRHRLLRRGRAYGGDGEADGDGETGLHFLCLGANISRQFEFVQHTWLNNAHFNGLYDGPDPVVAPRQNHDATFTVQAVPVRTRYRGLPQFVSIRGGAYFFLPGLQALRYLCEG
>NZ_CP024985|209435:263667|259059_260277_-|WP_030241062.1|DBSCAN-SWA
MSKTSRLNCIIPPHLLKRLLESQDSDVRQAALDTMLTTARLRGERAVRASFAGPAATATGNGRRTVFDCDQGSFLASAVMARSEDGPESADESANRAFGGLGLTRDFYKEVFQRDSIDGHGMRLDGYVHFSVKFNNAFWDGRQMVFGDGDGKMLGDLTRSLDVIAHELTHGVTEHTAGLVYHNQSGALNESMSDVFGSLVKQWSLKQSVDEADWLIGADVWTPGIDADALRSMKAPGHAYDNALFGKDPQPDRMSKFIHLPDTEEGDSGGVHFNSGIPNKAFFLAAVGIGGFAWEGAGPIWYESLKASSSETQFQDFADTTFQKAGELFGVGSAEQSAVLAAWQGVEIPISGVPAGVARGRSRTVDGNGGLSRQDGVAALTRQVGELSAQMTRLAKDVAALKGTG
>NZ_CP024985|209435:263667|215899_218158_-|WP_159038051.1|DBSCAN-SWA
MDRITGGVGVDAGAFVGLGWNISVISTPAPRDAMGTSGIAFGAAGTGPCLRPLPAVPRCACLVPTPVGHLVCGTMTPVIASLPSGVPAELGGYRILGILGAGGMGTVYLAKGHGRRAALKTIRPELLNDQALRDRFAREVAAAASVRGRYVAAVLRSAPLAAVPWLASEFVAASTLEQAVRRHGPLSVPAVCALAGALGRALTALESAGVVHRDLKPSNVLMALNRPRVVDFGIARMAGDHTLTSAGQRPGTAGYMSPEQVMQEQLGPASDVFCAGALLVFAATGRHAFYNGDQAGADFRIVHEEPDLKDVPGTLARVVRGCMEKRPADRPTASEIAAELDPRGVGAGAAKRWLPPSVVADAAEIERAATALAGRAGLITRRNVLSAGAATVVLGGASVGALVWGRSSSESPSGHDPAPRWSGEPGEVPPVLWSLEGAAVTPRYPPGDIGGAAYFEERGGGLAAYDIVSGRRRWRGPAVREVLGGSRPVALDTDGAVLFLAAASGAVLKRIKADADRLLAVDRETVYVLDHSGEIRALRSADGTQRWHGKLPVPGPVAAAGGHGLVTVVSATGAVVALSAADGARMWRYDISGADRPAPDTEACRPAMSSEAVVLGGGAALTALAPRGGGRLWQLAADERAGFGEPTATGDKLYVRDGAQLRAVDAVTGKAAWTVAAGAELAPRPGPLVAGASVHAALANPELGVLAVHTGRAAAQYVFAPAIASAAPWQGAAVAGRVVWQRGSSVSAIPAM
>NZ_CP024985|209435:263667|249872_252959_-|WP_078950731.1|DBSCAN-SWA
MANAQARVKLRDVPGWAVWLCLFGLAAGLFMILWYAADPPFRARPSQDGELLLQFPTNADTARAIVKEAGGSKLFQDGLVLDWRWFIPGYGAALAGAFGLGYLFLYRKSTRLWARRALFLTPVVVAADCVENIFLWKALDRIKADPDGPVLPWAGVLPTASERDLERNLQWATYFAQVKWALVIPLVAAAAVVVVTLYCRRVQDPSLLQSGREDHPRPVVAHTNRPAGETESQRSHPDVILPPAAPHDWEPRPEWTAPDPAKPHQAQAQDPADKTATRWRTRAYQPPGRQPAEVGFCVSGGGIRSASITLGALQALRGQLLQADYLVAVSGGGYTAGALQLALTGARLRDADGNPSVRPGLAEPADAFLPGSQEEDHIRRHAKYLADTPKERMHAVGAVLRGMAVSFGMLALLFAVAGQFLNVFYSHLPLTDLRRFMPQAKAFAPTCEVPDVPKCPGSTQMFLPSLEWYPNAWHPVLALFGLAGLVSVGAAFVGAGTMKSRPAWLRSIVNTIVAMALVVALIAVVLPAVIWFFAWLALEQGVVQNDGSGLSALAALTAVATAVGTWFTVVHKTVKEVRPDGEKAGLFGKSGPSLVVQVGTGWMKVVVCWLVLLLVAFFYLALMSWAAVYADSWDIWWKAGIPIALIVLAFVIDQTTFSLHPFYRQRLAGAFAVRRAVLKDGSVGALPYDYNHEPTPLHPYAQRVAGFPQVVFAASAAISLRNRTAPGRPAVPFTFASDYCGGPDTGWVRTDTLQNTAPALIGRDLTVQSAIAVSGAAFASAMGTQTMFMERLLALSNVRLGTWVPNPLYLAELAKYGPCRIMPRLPRVRRLRYQLQELVGWYSDTTPLLLCTDGGHFDNLGLVETLRLRCRTIYVIDSSGDTPPLATTLAQAVTLAYEDLGVKITFEEEGQNLLDLVPGSARPLPPETPMAALNARFSASCVVRGTIEYPEPVEFSPGTPADTKGTIVFVKASLTREMPYELLSYALREKAFPRQATFDQWFDHAQFDAYRELGHYIGTQAKEAISAG
>NZ_CP024985|209435:263667|240190_241399_+|WP_037689167.1|DBSCAN-SWA
MPVLLLTAFYLGLFGFEDLDEALTFVGRITGAGLIAASAISLLGSAAVMDHWFWKIFPYSGMVALVGTVAALLTNAMVLFEISNSDSLFYKTLFGLLTAGSAWTVFAVWRTLSKIPAPKRVATAVIASSVFAIANFGYQNLYQPSQHGARPAIKLTMGQPELNMDGKSFAVPVDITLENHSEVGFYIMGAEFHAMGQKVKVIEHDRLRQKWRDDAQKWKEYQERSPLSRREEHQDGQLLAAQPWMAPGGYIEASDSVAIRTLVRLPIDTQYDQVAFYATASLARKDRLGLDSVAFKSYSWKGGNVPQWVKRQKEFDSLIYVGRVHQNNSIDERTMDPRSVSIYWKFGTHGAEVSASITKKGDENREPREAEVRAVRDRYGLVDALTGPIQRSLWDIKSKSRQ
>NZ_CP024985|209435:263667|233062_233947_+|WP_158741069.1|DBSCAN-SWA
MLFSLSKPGVPWRTGLRSAAVVSLLAMGATACGAGGSSDNPQAGQAPQSTQATSTPDGKKTLDAPVAKGLGSLTSGNLTLLAFYDPSTGKETFSTTLPQYSEKNPWKRYSFSPDWKRHAWVKDGDLFVGSFTGSTITSAYDETPGVKIGGKPTFNGGKRAYRQPRFSADGKRIFALANDEKVYSADPSSPDQLTEEATLDQGSFFGGRSELLWDLTADGKVVKRPAPVHPERGGQATSPDGTKTLIYNGSGWFLKANGATGEPQLAFETLTDDTDKPVGSGPNPGMDVDIIGWY
>NZ_CP024985|209435:263667|234059_234371_-|WP_158741071.1|DBSCAN-SWA
MGETVMVRCCTAEQMRHFTDSVTEMVDRGRALRQLYAHQEEPPHRTRCARMTSGRINPISPACTTGERLAAERTVMLRPQSTLLRTLGTDRAVHCRWQCGGCW
>NZ_CP024985|209435:263667|236493_236775_-|WP_100660743.1|DBSCAN-SWA
MGRAAEMLGTTQGFLRAIGEACLITPLRSAGGHRRYSRYQLRIAARARELVDQGTPVEAACRIVILEDQLEEAQHLNVGYRRAAESANPTAAA
>NZ_CP024985|209435:263667|263199_263667_+|WP_100660746.1|transposase|DBSCAN-SWA
MSDGSCPGGGSTAVLGKKSSWRARHELTNAQWDRIAPLLPETGSPGGRWADHRTVVNRVFYRTRTGIPWRDLPERYGSWQTVYERHRRWSADGTWSRILRALQADADATAPDADGSWAVNVDSTTCRAHQHAAGARHAPPADHPEKAPLWLSSSC
>NZ_CP024985|209435:263667|224770_225178_+|WP_158741063.1|DBSCAN-SWA
MAGVGVAAAITMVAAGPAAHATPAGGAVPQVAPKAGETPALDCFHVEIGSNATFFAVRPLLDVVGVAGLELREQGSTTWTRMRETWGDVFRLDSNRPLRAPFSLRLTNELGVTTTYINIIPANWTPEQSYCGTGT
>NZ_CP024985|209435:263667|238982_239744_+|WP_030241098.1|DBSCAN-SWA
MPAAYEQYLVPVVFQPFAGDLAARAAALRPRRILELAAGTGVFTSALLVAAPSAKVTATDLNEAMVAFGSARSPGAVWRQADAQRLPFPDGGFDLVACQFGVMFFPDRIGAFAEVRRVLAPGGRFLFNTWGSLGAHAFEFALQAGLERAFPVDPPQFFRTVPHGYADPAVVAADLAAAGFAVEEEQELTLQGWAASTADLATGYLTGTPVRAAVEERGDGPAVRATVTEEMTARLGPGPVTAPMTAFVFRAAA
>NZ_CP024985|209435:263667|235480_235870_+|WP_030242126.1|DBSCAN-SWA
MSSKRSKNPALPVLDDAFRLASVKDAEESTRDLAARLATTELRRVSHPGRVTWEPTDQAEPVPVPPTVVDGEGDLWLRDRGTGTWTMPEFNPKEFPARCGEVLTWNQLAREFGPLTALADDRRIGGRRR
>NZ_CP024985|209435:263667|222940_223495_-|WP_158741061.1|DBSCAN-SWA
MRAAILTVAGSIIVGCLGLWSGVFSGKDDRDDPKPAPSASQAGPSSGGAGPGQVLPACGGKPGLDVTVEPKQLTVASDGSLTAEVNCTLGAGLHLSWIVQIDGVGKPVPHTNYYHKDDLGRPGPYTFDVHLSQAVPGSARTIYVVLTDDFSYRQLSDNRNPDGSLLKLPNGARKVSNSVLVKRY
>NZ_CP024985|209435:263667|226094_226304_-|WP_100661219.1|DBSCAN-SWA
MPEDPDELVDAIAVAVRAGDDRRIGLLLDRFKEVAGLSHLIRLRERLCGAGGAARVSARGIWWSATRTW
>NZ_CP024985|209435:263667|245713_246715_+|WP_030241086.1|DBSCAN-SWA
MPLKGYGVLAARAVDRRREGSRDTPHYQIHLTDNAGTHYRAAVNVESQQAPSELLYLADDDFRHPVTELLPPAGSGWTALVSQAGKASLDFIRGNLFDPAAMRMLPPDVEGADNDLADLLDHYVQRAIADPTAAVYVFGQRFGPEKNIPDKVFGFRPGNGVHDIHMNQGNSGRFHSDNGVWQDGALFVHLPAENRWIAIFLAFQSQAWHTADQTGHPLDTAPLRSGDRDEPLRIMAALVHPSGPAPEAVTVLNVSPTPVDLQGWRLTDLNQHTLPLPAGTLQPGGTLTVPGGNGFHLDNQGGTITLVNPDGIKVHGVAYTAREGAREGRTITF
>NZ_CP024985|209435:263667|221584_221851_+|WP_078950757.1|DBSCAN-SWA
MSPCGVVKWFDPDRGTGLISQDGTGPDIRAEARAIHGKGPCLRPGDRVLFDLTHDSAGLRADNIHRPEDALSQDGPGQQTDRRGNSRL
>NZ_CP024985|209435:263667|211369_213529_-|WP_158741022.1|DBSCAN-SWA
MPLVLPLLPDDPARVGTYTLMGRVGGGGMGTVYLARTGSGRLAAVKTVRTELKDRPGFRDRLLLEAEAVRLLGSSHTAAFLAVDAEASLPWLATGYLIGPSLSEAVAVAGPLPVAAVVMLGAAVADTLTTLHRAGLVHRDLKPANLLISAQGPKLIDFGLARALGGPPLTAAGEPAGTPSYMSPELVRGEEHGPPGDVFALAAVLVFASSGHGPYDGGPGRDALRLLRDGAPPELTGVPDTLREVIRSALSPDPRDRPTLDELAAHWGPYEAARFSESLPGEVLADMSRRVDELASLGGTPLREDSPPLRPSYPSRRVLLAGAAAVAAGGASALWLTGRSPGFGGGSGAPGPVPSPSGGLPGGSPRQQWSVPVSAVYGPPVATEELVLLPGETVRGLSPTSGGMLWEVPSTRLRVAASGRRLAALAFDEELTPAAGYLDPLSGRLMPDAAGPHELGALSLYSEVLNADADTLYIRAYYEADKDRAEPWLLAYDLAAHRLRWRTRVAWGYTDRTEALYFRAVVANGRLIGSDATRVFAVDVRDGRFLWVTRLRSDAEAAAPGASGGVYPPVVSEHHVFDVSQVITAVDLLTGAPTWTLKPERDQTLLTSPVCVQGTVHIASHAFTAFEESTGRKLWTYEPGPSFQRIAVPGPFRGELYAAVSGGGQAVVAVDLAQRRASWTLSAQAAGMPDGPSDLTHRDDRLYLQAYQRLTAVRIDTRR
>NZ_CP024985|209435:263667|209435_209975_+|WP_100660738.1|transposase|DBSCAN-SWA
MRYPQGGGLTAERQAFRERVRMEAVAMFAVGRGSGEVAKELRVSVRSVQRWRQAWSAAGQDAVRSRGPACRPKLSDALFAVLEEELAKGPVAHGWPDQRWTLARIKTLIGRRFHKSMTLSGISQMLRRHGWSHQVPARRAVERDEAAVDGWVKDVWPHVETPRRRSKSGSSSKTKPDSR
>NZ_CP024985|209435:263667|261099_261411_+|WP_030241047.1|transposase|DBSCAN-SWA
MVSKYTKRYSVEYKRDAIALVHSSGRTVTEVARELVISSESLRGWVKKDRAAQATAAGSVRPGQRGDDRDEELKRLRKLTAEQAKAIEILKKATALFAKESDR
>NZ_CP024985|209435:263667|253091_254954_-|WP_078950730.1|DBSCAN-SWA
MRKAPFHARTRTHPSAHAEGKGACSPFVRLHDNVALAVDRKLGWQHLPTPLGLLTLMGLRDNLRRKNLHDTNGYPAQGVPDIEPPAARHLTERTADGSYNDLDNPRMGMAHSRFGRNVPPDVTFPEPEPQILTPSPREVSRTLLTRDEFIPATSVNALVAAWLQFMIRDWVSHGQGAIDDPWRIELEDGDPWPTQPMLVPRTLPDTTRTEDGDGLPPTYINENSHWWDASQLYGSDLATQRRMRSGEKGKLKAPRDGMLFADAPELDPANTPGFWLGLLMMHHVFALEHNAICDRLSREFPAWSDEQFFQRARLINAALIAKIHTVEWTPAVISHPTTVTALRANWYGLLGERVQRLLGRISGNELLSGIVGGNTEHFGVPYSLTEEFVAVYRMHPLVPDDWSFRSAADDSLLQETNFRELTGRRAYEVFANHGLPDLFYSFGTSHPGLVTLHNYPKFLQEYQRPDEKLMDLAAVDVLRIREMGVPRYNEFRRRLHLEPAADFATLTDNPVWAEEMRRIYDDDIEGVDLMVGMYAEPRPKGFAFSDTAFRIFVLMASRRLNSDRFLTRDYTPQVYTQAGLDWIENNGMTSVMLRHFPELRSPMRAVDNAFTPWNTLHPVT
>NZ_CP024985|209435:263667|209899_210547_+|WP_158741024.1|transposase|DBSCAN-SWA
MAARGNTAAALEVWIVFEDEAGFSMTPPTSRTWSRRGTTPVIRVRGRSQRRFSSAALCCHKPGERSRLIYRLKRHTDHKSGGRKCFAWTEYRDLLIAAHQQLGGPIILIWDNLNVHKERRMKAFIDAQDWLTAYHLPSYAPDLNPVEGIWSILRRTSQANTAFTDPSHLMRRLRHGLRQIQYRSDIINGCLTATGLILRSGSDGPYCEPPQHALL
>NZ_CP024985|209435:263667|261434_262133_+|WP_158740998.1|transposase|DBSCAN-SWA
MEKANCPVTLLCKAMKTARSTYYAWAAGIEAREARRRADKALAHAITVIHLASRQNYGVPRITAELRRQGRRGNHERVARIMREHGIAGNSRRTGRRSLTKADSKAAPSPDLIGRDFTAARPGAKIVGNITYIPTAGGRLYLASWLDLATREVIGYSMADHHRADLVVDVLDMATALGRLEPGCVIHSDRGSEGGFNRPSQHPDLGGVRRGHGGLEFEDQRCSGGAASAVAR
>NZ_CP024985|209435:263667|236051_236255_-|WP_030242128.1|DBSCAN-SWA
MATGTVKWFNAEKGFGFIAQDGGGPDVFAHYSAINSSGFRELQEGQAVTFDVTQGQKGPQAENITPA
>NZ_CP024985|209435:263667|256928_258245_-|WP_051841516.1|DBSCAN-SWA
MSSPGSPASASSRRASQQIAVTVRATVPPDRVAEVQEVLAEANRRHAGGEFIHFAEMAGVHFARLVLVPEETDHTGQTMPASIVYMSEADAPLDAHLADLVAKAGSGLGKVFGHCRNYPPDGAPDAARVAWLRAHCVSSDAFYVNTVGRSLHQIQQEARLREAIQEFLDRRGAEQATADPAEVRAAIQRYVAGRPDLAWARSGPTPPALRWQIREAVHLAGVPLIALALLPVILIALPVWAVVLRWRERGDVPSQEHPSRDHVARLAACEDFATQNPFTAVGLVKSGRFRRATLTGVLFAVDYGVRHFFNRGSLAGVKTIHFARWLFLDDKRRVIFASNYDGSLESYMDDFIDKVAWGLNAVFSNGHGYPRTRWLLWDGAEDELAFKHYLRCHQLPTQVWYSAYDALTTRNLETNASIRAGLFAELGPAETRAWLALF
>NZ_CP024985|209435:263667|227355_229182_-|WP_158741067.1|DBSCAN-SWA
MVKAGRPQGGPKGETDEANELAVFLRDLTQDFTVRELAERYKISKTSWGEYRSGTKTIHLHLLKRLVHDLVRDERARAARWALAQRLHEQATTAQQPLGPDEPNTAMEGVTAAQAAAQATAALQDAERLVHILLGVIAGLQMPSQHGTAPGADAAGLASAADQAATDLREAHHRLDQVRLVQDAVRRVRDEATAHDDPSGAADAASRADDAGRSGNDEHLPVPYTAASREASAILIVSRAALVEQYAAARLLSARAAGVHAIEPTAVQNTPRGALALTSPPRSPTAVSPPSDRSRRRRQIVMMAVAVTLAASLSAVAAVTLVRNGQHPPLEQANRPTPAPAASLPPPTLSPSPPASPTPSPSPDLIDPTSPPNPTRSTETSVTAVPDDYLGTWQGEFTKPGDKAPTLRRIEIRKGAVGAETADILTSTASSLCQSKGTLISAGTLLVLTTNPTSGIPSHLCTTNADITLRRQGDTDLTWKSEGTTATLHRTAPQNQTIPAPFIGTWRAQDGNDTTSSVRMTINQGTPGHARAEFVWDGDAHHCEGFSVLASIGDALTFSPETVTSSEPQRFCTQTPTRLVTQSQGNTLHVEWADDGGFFRSFTFHRVG
>NZ_CP024985|209435:263667|241376_243197_-|WP_030241094.1|DBSCAN-SWA
MQALRLDWAGGAPRLRAAEAMARHGLVTTVSSRAGTAVVVGWVGSARDRVAGARGLLDAVGRPGATPRLPIGDYAAVLVYPDRIVLMRDCHARIPLFFRESGGRVSAVSTSARCLGDFERLEHGYFCRYLTGNLAQPHSGLTPFSGVHRILGGEVVELSVTGQMRGRVRGRVGEADALRESTADGLRLSGAGKNLRLALESAVGRRVGRMTVCHVSGGTDSTSIALLAARLLGRGQGRGEDLALLAGRFDTGELAGERSYLEEAMKEIRRHAPAARPVMVDAGDVADFDDFEHHAGDADEPHAHAFRAPFWSRLHGAAAELGCDILMTGCGADPIVDANPLHLHKLARTGQLRQMTKQARAWAAGTERGVRDVVYDYVMRPSLPLAAERITALVHRGTVLGGLGSFARPRWLRSGFAAAHGYREASIAESRFVFGRRPEQSFLDAANYLAAPDSVSWHRARQDGFFLSHPFLDREVTATMRSLPVAATFHPGRPKAVLREAMEDLLPSRIRDRAVKVPFDQLYARGLRKHGDELIDLCRSARHPLVEEMFDVEVLCRAVREAQLGVGNAESWDRMNSSLALVAWLDGLAAPRPRAPGAPVIDGSCS
>NZ_CP024985|209435:263667|218542_219502_+|WP_030241633.1|DBSCAN-SWA
MDISSFISEDFGSVVAGGAALLAVPGVIVAGAIQGKRALQGAQAQAEAALRAAHEQAAKALEAAQAQAQATLETGRLQAQATLEGVREMSREAHAQWQRDRCEDIWAAFVAELDLLKAKEQATSHESEVADLLKAYAMVELMSPPVVLEQASRARNKAIEVDLMLFTLRMQARDMEQLELAKQRLRSDVTQGSGIADTRGLLAELVPGPDGDDMVDSPGSPEEYEDMRERFERCRAASDALEALAAVERAQGVQDAGERARQTLLAAGFRETQASSLVFTAQLDRDEQQQILAADKRELTRLRNVFVKEARKELDALGA
>NZ_CP024985|209435:263667|243198_243795_-|WP_106979799.1|DBSCAN-SWA
MTRMLSPHCRVTGMSNGALISDWRRRTRFLGMTATDVEKFIVGSAEERAELVTDLIRTGCATACRKAYSDAEVGLWLRGVHLSIRTVGFGRVLRLLSLAAPVCARADLPSAEEVARLKRALRTHGRRSWFVNDDCKAEAVTAFVLLRRCGLDAVLHVGVREHPFALHAWSSSAGVCIPDADPRGHGFTPVLSISCGGR
>NZ_CP024985|209435:263667|210600_211149_-|WP_030241640.1|DBSCAN-SWA
MAELGPVVWPPAPLRTERLVLREPEARDRAAFVDLFASSEVRTYLGGPRPRAELENAVPEVPGRRPGVFVVDHDGAMIGIVTLDRRGAERPGHVRPDAGEAELSYMLLPEAWGRGYALEACSAALGWFADVFPGEPVVLCTQVANDRSVRVAEKLGFTEMERFEEFDAEQWFGVWSSVPWSG
>NZ_CP024985|209435:263667|260658_261006_-|WP_051841513.1|DBSCAN-SWA
MKADEVRVHDSQTEELLWQATGPLTPEGVRGDVTRRRPEQFGRATGGQQPAVRPKLPAVSVAGAERGGRGEVLDTAEVAAAQLPAGTYWTRKGPRTAQEIDAQYACTDPPPGDGS
>NZ_CP024985|209435:263667|244377_245460_-|WP_030241089.1|DBSCAN-SWA
MDTAIRIEVLPARLGDCLLVECARGSGPPWRMLVDGGPPGTWPRLEKRLSRLEPDERHIDVAVVTHIDSDHIGGMLPFLRSEYAEDVGDYWFNGPPHLPAEGRVEGSVAQGESLVAALLGVSAGPVLPWNRAFGGGPIDTGDEFGFIEVPVPDGPHITVLSPTNERLVMLEREWSETIDHARRGWQADMRPDVLEPLGDLAAVAAHETTDDTTAPNGSSIALLIEHHGARAVLGADAFGAVLGGGLKGVADHRGLRALEVDAFKLPHHASRRNVTEALLEVAPARHYLVSTNGDTYHHPDDEALARVVLSAPDGPTLWFNYRTQRTARWADPELCERYGYSARFPADPETGAVLELPATA
>NZ_CP024985|209435:263667|248668_249817_+|WP_030241080.1|DBSCAN-SWA
MATLDAYGPPGNLDDLDDFGRKAWNKFISDTVDEAIQGPDPRQVLNDSPRPQFYNLTGTDTASDVQRVSITWTSFPRIIKITSVGDLQRWQRADASRDVQDEYCEWSVTRDGSGKITRVTFTCEGPEYWEVLAHTNPDKVVDLYRAFISPDVRKEDLFSPSGRYQPRNKWNDSTSHGAMHLIQANNTLGAEIELAAAATIRRVVNGQELSTEQELVNCSKYGAAERNSDPHIGAGVNALARQRADISLADPVGLYFDDLSTDGWETPDGSDPRSYWTYVRGDSEHRVRAVYEVPQDKGFAVGDITIGGRPIEFGAQIADFITIRLTGLACRFDGSTAQPQTACKEFPAVDVRPEGFGASAFSTSGRFLDPRPTLSYRSSRAT
>NZ_CP024985|209435:263667|229332_232239_+|WP_100660740.1|DBSCAN-SWA
MAHLLSRNRTKPGPGTPPARLRRIGVLLAGAITAGLLSAAPASADPAPAAPITLVSVTATADDQLYALAADHTAVYRWNGKGTDWTKVGGPAQDLYVGGAGLFATSLGSGALNKYNGQPGDWSQIGGAGADFAVTGDHLYGLNPDRSAVYEWNGTGTDWTRIGGPAQDLEAGGAGLFATSPDGKLHKYNGQPDTWSEIGGAGADFAVTSDHLYGLNPDRTAVYEWNGKGTDWTKVGGPAQDLHAGGAGLFATSPDDKLHKYDRRADTWTEIGNAGKAFAVGSTRLYGLASDGNSVHRWSGQGADWTALGAPSAPGAPVPQAADPSPEPQSAPPGMGSEAQDGAEAESVPEAGSPSSVRGALSDIAGPELSVTAKGDLYALAPDHGSVWKHEGDNHWTKIGGPAESVHAGRLGVFARHPDTGAIYRYDGEIGRWSQIGDASADLEVTGDHLYRLSSDRSAVFEWSGQGTDWTKIGGPADQLYAGGAGLFATRPDTGHLYQYNGTPDHWTEIGTPGAAFAVSDEHLYGLSPDRSAVFEWSGQGTDWTKIGGPADQLYAGGAGLFATRPDTGHLYQYNGTPDHWTEIGTPGAAFAVSGEHLYGLSPDRSAVFERTSGDNWQYRGGPSEALQAVRDEDTLRELRGDDYVRQYRQASILADTKLMEWLAQNGAGILLELLGVKDIEKCLSAPGKEKIKPCLLAAANFSTVITAVRKADKVQDAIKTVAVGLPRFRSEVVAARNVVVQAREILDRNAKDLADDFTVNKPDRADCRRNGAGWLDLGTRDVAHGSRATAMNACLDTAYLTAHAQRGSPTTAAVRPPGYNWATATAGYLRIKDIPQRINNCHLLGKQLTGSGEDLDNLVTCSRAANAQVKGDEGFANDMKALEGEVKKAVDAGQVVRYQVTPVYSGPRTVPVKLEISAVGMYPDGRPGGVLIKRAVENKLFQPQTQKWHNLGLWVMNGKAVPTGNTP
>NZ_CP024985|209435:263667|262129_263086_-|WP_100660745.1|transposase|DBSCAN-SWA
MSHRNARLTVFGRRLLVERVASGRPVAHVAAEMGISRATAHKWVRRWRDNGPAGLHDRSSRPRTTPHRTSAEVEARVCDLRRARKLGPARIGPVLGLPASTVHRILTRHGLNRLSFMDRPTGTLIRRYEREKPGELIHVDVKKLGRIPDGGGHKALGRQAGRATRNGMGFDYVHSAVDDHSRLAYSEIHPDEKVATCAGFLTRAAAFFHHHGITRIERVLTDNAWAYRKGLAWKTVLAHLGASGKLTRAYRPQTNGKVERFNRTLLDEWAYLRPYTSNDERTAALADFLHTYNHHRCHTALGGHPPISRVNNPAGQYT
>NZ_CP024985|209435:263667|213563_215255_-|WP_159038050.1|DBSCAN-SWA
MAPETVGGRVSSQAADIYALGVLLAHATTGRFPFGEGPPEVLAYRASHGKAELHGLPADLAEAVAAALAPVPGDRPTAAELSQTSALTRTTPVADGPAPGKVIIALAAQAQETADLGEGADRDLPRRTDVATRPLHRAADGPTRSSATGQTSPAGPLTRRALLSRLATGVAGAVLGAGTSLAWTATREPADRSLPDRPLATAPLPGLPPTALWRFDDVTARTTLLRVAGAGRYLVTRGETLHAHEVRSGKEVWERPIAFGRANPVLLVGGGRILVQTRDALVLCSLGDGRTHWIDRTFHTQNTTVLELLAVEGDTVWLHMGPAAGASATTHALAAFDLAARRELWRSELPADFVYELSLTPTPAGLLVEVLPEVDPHRDPYGTRKVPLACFDRTTGRSLWQRTYEGVYSGPASAVDETGRFYVLSTGRARAYDATPGSQLWESTLRFGGQHSPLLLTGTLLCETDPVNGVVALDRDTGRTVWQQRLDEPLQWFLLGTMATSASGRTLFVPTRRQLAALDLRSGERLWQMAFVGREDPSPLQLLATPDVLIVAQPSVVFALPAV
>NZ_CP024985|209435:263667|225684_226029_+|WP_159038052.1|transposase|DBSCAN-SWA
MSECDDLDDGEWAVIRALLPRCGPGGPDYRAVVNGILWQQRGGRRWHDLPARYGPWHRCAERLRLWQTDGTWHNVLTSLAASRPLPRRTEQTRDTPKSSLAREEIDDWNSPWLP
>NZ_CP024985|209435:263667|254990_255371_-|WP_030241072.1|DBSCAN-SWA
MNARSFARYSLAGIRLVNGVAALLAPQVVARRLGADGMQPALSHVLRMFGVRTAFIGAELLFLQDPARIARALHVGTVIHTSDALSAAAAGRCGMLAPRAAATATAISTVNVALTLVADWPRRGTG
>NZ_CP024985|209435:263667|258721_259024_-|WP_030241064.1|DBSCAN-SWA
MKVTLATHGGLAATVNLRLPPKVLDTDTLAENAASELARLVAAAVVSPVADQPSRARDAMSYTITVEDGGRSTVLKQSDAAMTPAFAALLARLQEYLEQQ
>NZ_CP024985|209435:263667|246904_248566_+|WP_051841515.1|DBSCAN-SWA
MPDHAQLRRATAWMSGTAVEEGDAARVSVALPDSSGHFPPEPDIADGACGPGSTALEPGRLYRRISGRDDRARPVRDEELAELGDPMAVTFFRAGRFPTTVQELLSELPATAAASRKVYLVSEAGQISPGALGERDMRFAMTTAVEGNQVDLLVSTQAGGDPERGFLQVAGWDSAAKVFNFYARFESSWVWAGNSWHSLEPDSRGKGCFDSHVNGSAVMKELRIPWLNWQSERATIRLAEDDPLRQDQLFQQVIGAERLELTVRFLVTRWTAARLAAVTANGVVDHPDRLLRHLFTNTTVNLTSTDRQSSTITADSGELTLPSGFWLNQDLLFDDLRLFTQAAPPRAPAAAYLAGLTRFGFGLEEKFSGFSQPGDTFFAFVVPEAAHEDNEVVRQMVRKGLISARFAACALMVDFPNPVFSPARSLLMRYVPTTPTKAAELGEEVTRAILDAARTRNLPADSPEARFAAHWQVPEDAWPSVFGQRVDAYLRKVTQRVQTASGFDDYVRLAESRRRQFRRMKLHEFELTMPVTNIPPGAPPLAMREDGTVTELT

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100660738.1|209435_209975_+|transposase	transposase	NA	NA	NA	NA
WP_158741024.1|209899_210547_+|transposase	IS630 family transposase	NA	NA	NA	NA
WP_030241640.1|210600_211149_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_158741022.1|211369_213529_-	protein kinase	T2AWK4	Cannes_8_virus	3.9e-07	25.0
WP_159038050.1|213563_215255_-	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_159038051.1|215899_218158_-	PQQ-binding-like beta-propeller repeat protein	T2AWK4	Cannes_8_virus	4.3e-09	26.4
WP_030241633.1|218542_219502_+	hypothetical protein	NA	NA	NA	NA
WP_158741016.1|220278_220752_+	hypothetical protein	NA	NA	NA	NA
WP_078950757.1|221584_221851_+	cold-shock protein	NA	NA	NA	NA
WP_158741061.1|222940_223495_-	hypothetical protein	NA	NA	NA	NA
WP_158741063.1|224770_225178_+	hypothetical protein	NA	NA	NA	NA
WP_159038052.1|225684_226029_+|transposase	transposase	NA	NA	NA	NA
WP_100661219.1|226094_226304_-	hypothetical protein	NA	NA	NA	NA
WP_158741067.1|227355_229182_-	hypothetical protein	NA	NA	NA	NA
WP_100660740.1|229332_232239_+	hypothetical protein	NA	NA	NA	NA
WP_158741069.1|233062_233947_+	PQQ-like beta-propeller repeat protein	NA	NA	NA	NA
WP_158741071.1|234059_234371_-	hypothetical protein	NA	NA	NA	NA
WP_030242126.1|235480_235870_+	hypothetical protein	NA	NA	NA	NA
WP_030242128.1|236051_236255_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.6e-17	65.7
WP_100660743.1|236493_236775_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_030241098.1|238982_239744_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_037689167.1|240190_241399_+	hypothetical protein	NA	NA	NA	NA
WP_030241094.1|241376_243197_-	asparagine synthase	NA	NA	NA	NA
WP_106979799.1|243198_243795_-	lasso peptide biosynthesis B2 protein	NA	NA	NA	NA
WP_030241089.1|244377_245460_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_030241086.1|245713_246715_+	DUF2278 family protein	NA	NA	NA	NA
WP_051841515.1|246904_248566_+	hypothetical protein	NA	NA	NA	NA
WP_030241080.1|248668_249817_+	hypothetical protein	NA	NA	NA	NA
WP_078950731.1|249872_252959_-	hypothetical protein	NA	NA	NA	NA
WP_078950730.1|253091_254954_-	heme peroxidase	NA	NA	NA	NA
WP_030241072.1|254990_255371_-	hypothetical protein	NA	NA	NA	NA
WP_030241070.1|255512_256910_-	peroxidase	NA	NA	NA	NA
WP_051841516.1|256928_258245_-	hypothetical protein	NA	NA	NA	NA
WP_030241064.1|258721_259024_-	hypothetical protein	NA	NA	NA	NA
WP_030241062.1|259059_260277_-	M4 family metallopeptidase	NA	NA	NA	NA
WP_051841513.1|260658_261006_-	hypothetical protein	NA	NA	NA	NA
WP_030241047.1|261099_261411_+|transposase	transposase	NA	NA	NA	NA
WP_158740998.1|261434_262133_+|transposase	IS3 family transposase	NA	NA	NA	NA
WP_100660745.1|262129_263086_-|transposase	IS481 family transposase	NA	NA	NA	NA
WP_100660746.1|263199_263667_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	6.8e-18	41.9

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP024985|6389494:6396563|DBSCAN-SWA
AATGACGGCGCAGGAGCTGGACCTGAGGGGGGCCCTGGAGGCCGTCCTGATGGTGGTCGACGAGCCCGCGACGGTGGAGCACCTGGCCAAGGTGCTGGAGCGCGCCCCGCGCGAGGTCGCCTCGGCCCTCGCCGCCCTGGCCGACGAGTACACGGCGCAGCGGCGCGGGTTCGAATTGCGGGAGGTCGCCGGGGGCTGGCGCTTCTACACCCGGCCCGCCTACGCCGCCGCCGTCGAGGCCTTCGTCCTGGACGGCCAGCAGGCCCGTCTCACCCAGGCGGCCCTGGAGACCCTGGCGGTCGTCGCGTACCGCCAGCCGGTCAGCCGATCGCGGGTCTCGGCGGTCCGCGGGGTCAACTGCGACGGGGTCATGCGGACCCTCCTGCAGCGGGGTCTGGTGGCCGAGGCGGGCACGGAACCCGAAACAGGTGCGATCCTGTACAGGACGACGAACTACTTTCTGGAGCGGATGGGCCTGCGCGGCCTGGACGAGCTCCCGGAGCTCGCGCCCTTCCTCCCCGAGGCGGACGCGATCGAAGCAGAGACGCAAGAGGGTGTTCCGTCGTTCGATCCGGACGCACCGGATACCGATGAAGACGACAAGACGACGGAACTTTGATGCGAAGCAGCGGCAACGGCAACGGCGGCGGCAACAGGAACAGCGGCGGCGGTGGTGGCGGACGCGGTAACTCCCGCGGCGGCTCCTCCTCCGGCGGTGGCTACCGCGGCTCCTCCTCCCCTTCCCCCTCCGGCGGCGGCGGTAACTCCCGCGGTGGCTCCTCCTCCGGCGGGGGTGGCTACCGCGGCGGCTCGTCCTCCGGCGGTGGCGGCTACCGCGGTGGCTCCTCCTCCGGCGGCTCCCAGGGTGGCGGCTACGACCGCGACCGCGACCAGGCGCCCCAGCGCCCCCGCAACCCCCGCCCCGAGGAGCGCCGCTACGACGTCGGCCCCGAGGGCGAGCGCAGCGGCCGCAGCGGCCCCCGCGCGGGTGGCGGCGGCGCCCGTGGCGCGGCGGCCCGCGGCGGTGCCAAGGGCGGCCCCAAGACCTCCAAGACCCCGGGCATCGGCGGGGCCGGCGGCCCGCGCCGCGGCCCCGGCAGCCGCAGCGGCCAGTCCCGCCCCCGCGAGCTGGACGCGCGGATCGAGGAGCGCGTGCGCGACCGGTACGCCGACAAGCCCGTGATCAAGACCCCGAAGACCTTCCCGGGCGCCGAGCAGGAGGGCGAGCGCCTGCAGAAGGTGCTCGCCCGTGCCGGCATGGGCTCGCGCCGCGCCTGCGAGGAGCTCATCGAGCAGGCCCGCGTCGAGGTCAACGGCGAGATCGTGCTGGAGCAGGGCAAGCGCGTCCAGCCGAAGGACGAGATCAAGGTGGACGGCCTGACCGTCGCCACCCAGTCCTTCCTGTTCTTCGCGCTGAACAAGCCGGCCGGCGTCGTCTCCACCATGGAGGACCCGGACGGCCGCCAGTGCCTCGGCGACTACGTCACCAACCGGGAGACCCGCCTCTTCCACGTCGGCCGCCTCGACACCGAGACCGAGGGCATCATCCTGCTCACCAACCACGGTGAGCTGGCCCACCGCCTCACGCACCCGAAGTACGGCGTGAAGAAGACCTACGTCGCCGCGATCACGGGCCCGCTGCCGCGCGACATCGGCAAGAAGCTCAAGGACGGCATCGAGCTGGAGGACGGGTACGCCCGCGCCGACCACTTCCGCGTCGTCGACCAGGTCGGCAAGAACTACCTGGTCGAGGTGACCCTCCACGAGGGCCGCAAGCACATCGTCCGCCGCATGCTGGCCGAGGCCGGCTTCCCGGTGGAGAAGCTCGTGCGCACCTCGTTCGGCCCGATCGAGCTGGGCGACCAGAAGTCGGGCTGGCTGCGCCGCCTGACCAACACCGAGGTCGGCATGCTGATGCGCGAGGTCGGTCTGTAGGACCCCCGCAGCACACCGGCACCCCCGCAGCACACCGGAAGCCCGCGACGCCCCAAGGCGCCGCGGGCTTCCGTCTTGTCCGGGACCCCCGAACCTGTTTATAGTCAGAGTGACTATTAAAGGAAGTGGGGCTACAGCCATGGGGTGGAGTACCAGCTGGACCGAGGTGCTCGGCTTCGTCACCGGAGCCGTGTGCGTCGTTCTGGTGGCCCGTCAGCACATCGCCAACTGGCCGGTCGGCATCGCCAACAACGTCTTCTTCATCGTGCTCTTCGTGCAGTCCGGGCTCTACGCCGACGCCGGACTGCAGGTCGTCTTCATCGCCCTCGCCGCGTACGGCTGGTGGTCCTGGACCCACGGGGGTGGACCAGGAACCGCCGACGCCCTGCCGGTGCGCCGCACCACGGCCACCGAATGGGCCTGGCTGCTCGCGGCGGGGGCGGTGTCGGTCGCCGCGCTGACCCTGCTGCTCGGCGGGGTCAGCGACTCCACCGTCCCCTTCCCGGACGCCCTCACCACCGGGCTCTCGCTCATGGCCACCTACGGCCAGTGCCGCAAGCTCCTGGAGTCCTGGTGGCTGTGGATCGCCGCCGACCTCGTCTACATCCCGCTCTACGCCTACAAGGGCCTGTACCTGACCTCGGTCCTGTACGTCGGCTTCCTCGCCCTGTGCGTGGCCGGACTGCTCGGCTGGCGGCGCAGCCTCCCGGCGGCCGGCGCCCGTACGGCAGTGGGAGCGGCGGCATGAGCGGCGGCAAGCGCTACGGGCACGGGCTGGTCCTGGGCAAGTTCTACCCGCCGCACGCGGGCCACCACCACCTGGTGCGCACCGCCCAGGACCAGTGCGAGCGGCTCACCGTGCTGGTGTGCGCCGCCTCGGTGGAGTCGGTGCCGCTCGCCGACCGGGTGGCCTGGATGCGTGAGGCGCACCCCGGCGCCGAGGTGGTCGGCGCGGTGGACGACGTCCCCGTGGACCTGCACGACCCGGCGGTCTGGGAGGCGCACATGGCGATCTTCCGCGGCGCGGTGGGCCGGCGCGTGGACGCCGTCTTCACCTCCGAGGCCTACGGGACCGAGCTCGCGCGCCGGTTCGGCGCCGAGGAGGTCTGCGTGGACCCGGCGCGCACCCTGTTCCCGGTGTCGGGCACGGCGGTGCGCGCGGACCCGGCCGGAACCTGGGAGTTCCTGGGCCCGGCCGTACGGGCCGCCCTGACCCGGCGGGTCGTGGTCCTCGGCGCCGAGTCCACCGGGACCACCACCCTCTCCCGGGAGCTGGCCGCGCACTACCGGCGGCGCGGCGGGGTGTGGGCGAAGACCGGCTGGGTCGCCGAGTACGGGCGCGAGTACAGCGAGGAGAAGCTCGCCGCCGCCCGCGCGGCGGACCCGGCCGCCTCCTGGACGGACGTGGCCTTCACCTCGGAGGAGTTCCCGGTGATCGCCCGCCGCCAGGACGCGGCGGAGGAGCGGGCGGCCCGGCTGGGCTCGCCCGTGCTCTTCTGCGACACCGACTCCTTCGCGACCGGCATCTGGCACGAGCGGTACATGGGCGGGCGCAACCGGGAGGTCGAGAAGATCGCCGAGCTGACCCGCCGTGACCTGTACCTGCTGACGGACGACACCGGGGTGCCCTTCGAGGACGACGGGCTGCGCGACGGGCCGCAGCTGAGACCGTGGATGACCGCCCGCTTCCGGCGGGAACTCGCGCGCACCGGAAGGCGTTTCCTGGTCGTGAGCGGGGACCGGCGCCACCGGCTGGAGACGGCCGTCGCGGCGGTCGACGCCCTGCTGGAGGAGGGCTGGCAGTTCGCGGCCCCCCTCCCGGAGCGACGGTGAGCGCGGCCGCGGCGGGCCGCGGGGACGGCGGCGGTGATCCGGACGCCGCGCGCGCGGGCGGGACCGGGACCGGGCCCGCGCCCTACGACCCGTACGCCTTCGAGCCGTTCGCGGTGACCGTCGACCTCGCGGTCCTCACCGTGCGCGGCGGCGTCCTGCACGTCCTGCTGATCCGGCGCGGGCAGGAACCGTACGCGGGCGCCTGGGCCCTGCCCGGCGGCTTCGTCCTGCCGCGCGAGTCCGCCGAGACGGCGGCCCGCCGCGAACTCGCCGAGGAGACGGGCCTGGCCCCCTCCCTGGTCGACTCCCTCCACCTGGAACAGCTGCGCACCTACAGCGAACCCGACCGGGACCCCCGGATGCGGGTGGTCTCGGTGGCCTTCACCGCGCTCGTCCCCGACATGCCCGAACCGGCCGCGGAGGGCGGCGGGGACGCCGACCGGGCGCGCTGGGTCCCCGTCGGGGAGGTGACGCAGCCGGCCTTCGACCACGCGCGGATCCTGGCGGACGCGCGGGAGCGGGTGGGCTCCAAGCTGGAGTACACCTGCCTGGCCACCGCCTTCTGCCCGCCCGAGTTCACCCTCGGGGAGCTCCGGGCCGTGTACGAGACCGTCTGGGGCACCGCCCTGGACCGCCCCAACTTCCGCCGCAAGGTCCTCGCCACACCCGGCTTCGTCGAGGCCGTCCCCGGCGCCGCCCGGCTGACCGGCGGCCGCGGCAAACCCGCCGCGCTCTACCGGGCGGGACCGGCCACCGCCCTCCACCCGCCCCTGCTCCGCCCCACGGAAGGCCCCGCCCGATGACCACCCCGATGCCGGCGCGCCCGATAGCGGGCAAGCGCCCCGCCACCGGCGCCCTGATCGGCCTCGCCCTGGGCGACGCCCTCGGCTTCCCGACCGAGTTCAACGACGTGCCGTCCATCCTGGCCAAGACCGGGCCGTGGCGGCAGATGGCCCTGCCCCGCCCCGCCCTCGTCACCGACGACACCCAGATGACCCTGGCCCTGGCGCGCGGCATGCGCACCGCCGCCGAACGCGGCCCGGTCGGTCCGCTGCGGCTCGCCCGGCCGGTCCGCGAGGAGTTCGTCGACTGGTACCACTCCCCGGAGAACAACCGGGCCCCCGGCCGCACCTGCATGGTCGCCTGCCGCCTCCTCGACCACCCCGGGCGGGACTGGCGCGACGCCAGCCAGACCGGCTCCAAGGGCTGCGGCGCGAACATGCGCGTGGTGCCGGTGGGCCTGGTCCCCGGCTGGACGGAGGAGGAACGCGCGGGCGCCGCCCAGCTCCAGTCGGCCCTCACCCACGGCCACCCCACCGCCCTGGCCGCCTCCGACCTGACGGCCCGCGCGGTCCACCTGCTGGCCCGGGGCACCGAGGTGACGGGCCTGGTCGGACGGCTGCGCTCGTACGCCCTGGAGAACCGCACCCGCTACCACGAGCGCTGGCTCGGCGACCTCTGGCAGCGCACCGCCTCCGACGCTTCGCCGGAGTCGTTCATCGCCCGGGGCTGGGACGAGTGCCTGGCCGCCTTGGACCGCCTCGCGGCGGCGCTGCGCACCCCGTCCCCGGAGACCGACCCCTGCCTGGCCACCGGCGAGGGCTGGATCGCCGAGGAGGCCCTGGCCACCGCCCTGCACTGCTTCCTCCTCTTCCCGGACGAACCCCTCCTCGCCCTGCGCCGCGCCGCCTGCACGGCGGGCGACTCCGACTCGATCGCCTGCCTGGCCGGCGCCTTCGCGGGCGCCCACCTCGGCGCGGACGTCTGGCCCCGCGACTGGGAGGGCCGCATCGAGTACCGCGACGAGCTCCTCTCGTTCGGCACCCTCTGGGACGCGTGAGCCGTGCTCGACGCGATGACCCTCGACCTGACGCCCGTCGTGAGCCGTCAGCCCGACCCGCTGCTCTTCGCCACGGTCTCGGGCGCCCACCTCTACGGCTTCCCCTCCCGCGACTCGGACGTCGACCTGCGCGGCGCGCACCTGCTGCCGGCGGCCGCGCTGCTCGGCCTGCGCGAGCCGGAGGAGACCCGGACCCGGATGTGGGACCACGACGGGGTGGAGATGGACCTCGTCACGCACGACCTGCGCAAGTTCGTCCGCCTGATGCTCAAGCGCAACGGCTACGTACTGGAGCAGCTGCTCTCGCCGCTCGTGGTCCACACGACGCCCGAGCACGAGGAGCTGGTGGCGCTGGCGCCCGGCGTGCTCACCTCCCACCACGCCCACCACTACCGCGGGTTCGCCACCACCCAGTGGCGGCTCTTCGAGCGCGGCGGCGAACTGAAGCCGCTCCTCTACGCCTTCCGCGCCCTGCTCACCGGCATCCACCTGATGCGCTCGGGCGAGGTGCAGGCGCACCTGCCCACGCTGCTCGGGGAGGTGCCCGAGGCCCCCGCGTGGCTGGCCGGGCTGATCGAGGCCAAGGTGACCGCCGAGCACGGCGGGTACGACGGTCCCGCCGTGACGGCGCCCTACGAGGCGCTGCACGCGGTGCTCGACGCGGCGCAGGCGGCGACGGGACTGCCGGGGGAGGCGGGGGCGTACGGGGCGCTCGACGCGTTCGTGGTGCGGTGCCGGGAGCCGTTGGCGCGGTGACCGGCTAGCCCCTCGGAGCCGGGTCCAGGGCGGCCGAGGCGCGGCGGGTGCGCCGGAGGTAGTCCGCCACGCGCGGGAGGTCCGGTTCCGCGGGGAGCGGGGTCGTGGTGAGGGCGGCGTCGGTCTCCTCGGTGAGGCGGGCCATCCAGGCGTCGACCTCCTCCCAGGTCCGCTCGCCGCGCCTGACCGCGAGCAGGCCCTCGCGGTCCGGGCCCGCGTCGATCGTCAGGCGGCCCGTGCGCAGCAGGTCGCGGCAGGAGATCAGCAGCCGCAGCAGGTGCATGGCGTGCTTCCAGCGCGGGGCGCCGTGCAGGCGGACGTCCGCGAGGAGCTTGCCGTGCTGGGAGACGGCGTAGCGGCTGAAGCTGGTGTGGGCCCGGCGGGAGAGGAACGCCCCGCGCAGGGAGAGGAGTTCCTCGCCGGCCGGGGTGAGCCGTTCGACCAGGGGAGAGTGCAGGCACTCCAGGATGTTCGGGTTGGCGCGCAGGGCCAGTTCGCAGAAGCGTTCCAGCTCCCAGGAGAACTCCTCCTCCCGGGGCCCCTCCACGTGCGTCGGCGGCTTCTCGAACCGCCAGAACAGCGGGGTGGGGGCGAGGAAGACACCGCGCCGGTCGGTGTCGCTCGCCCGCGTCGCCAGCCCGAAGGCACGGGAGCCCATCACGCAGGCGTAGATCGTGTGGTCCCGTACCAGGGTGAGGTCGTCCAT

Protein sequences of DBSCAN-SWA_3

>NZ_CP024985|6389494:6396563|6394072_6395101_+|WP_030240233.1|DBSCAN-SWA
MPARPIAGKRPATGALIGLALGDALGFPTEFNDVPSILAKTGPWRQMALPRPALVTDDTQMTLALARGMRTAAERGPVGPLRLARPVREEFVDWYHSPENNRAPGRTCMVACRLLDHPGRDWRDASQTGSKGCGANMRVVPVGLVPGWTEEERAGAAQLQSALTHGHPTALAASDLTARAVHLLARGTEVTGLVGRLRSYALENRTRYHERWLGDLWQRTASDASPESFIARGWDECLAALDRLAAALRTPSPETDPCLATGEGWIAEEALATALHCFLLFPDEPLLALRRAACTAGDSDSIACLAGAFAGAHLGADVWPRDWEGRIEYRDELLSFGTLWDA
>NZ_CP024985|6389494:6396563|6393374_6394064_+|WP_051841467.1|DBSCAN-SWA
MTVDLAVLTVRGGVLHVLLIRRGQEPYAGAWALPGGFVLPRESAETAARRELAEETGLAPSLVDSLHLEQLRTYSEPDRDPRMRVVSVAFTALVPDMPEPAAEGGGDADRARWVPVGEVTQPAFDHARILADARERVGSKLEYTCLATAFCPPEFTLGELRAVYETVWGTALDRPNFRRKVLATPGFVEAVPGAARLTGGRGKPAALYRAGPATALHPPLLRPTEGPAR
>NZ_CP024985|6389494:6396563|6392172_6393261_+|WP_030240238.1|DBSCAN-SWA
MSGGKRYGHGLVLGKFYPPHAGHHHLVRTAQDQCERLTVLVCAASVESVPLADRVAWMREAHPGAEVVGAVDDVPVDLHDPAVWEAHMAIFRGAVGRRVDAVFTSEAYGTELARRFGAEEVCVDPARTLFPVSGTAVRADPAGTWEFLGPAVRAALTRRVVVLGAESTGTTTLSRELAAHYRRRGGVWAKTGWVAEYGREYSEEKLAAARAADPAASWTDVAFTSEEFPVIARRQDAAEERAARLGSPVLFCDTDSFATGIWHERYMGGRNREVEKIAELTRRDLYLLTDDTGVPFEDDGLRDGPQLRPWMTARFRRELARTGRRFLVVSGDRRHRLETAVAAVDALLEEGWQFAAPLPERR
>NZ_CP024985|6389494:6396563|6395104_6395857_+|WP_030240230.1|DBSCAN-SWA
MLDAMTLDLTPVVSRQPDPLLFATVSGAHLYGFPSRDSDVDLRGAHLLPAAALLGLREPEETRTRMWDHDGVEMDLVTHDLRKFVRLMLKRNGYVLEQLLSPLVVHTTPEHEELVALAPGVLTSHHAHHYRGFATTQWRLFERGGELKPLLYAFRALLTGIHLMRSGEVQAHLPTLLGEVPEAPAWLAGLIEAKVTAEHGGYDGPAVTAPYEALHAVLDAAQAATGLPGEAGAYGALDAFVVRCREPLAR
>NZ_CP024985|6389494:6396563|6391567_6392176_+|WP_051841465.1|DBSCAN-SWA
MGWSTSWTEVLGFVTGAVCVVLVARQHIANWPVGIANNVFFIVLFVQSGLYADAGLQVVFIALAAYGWWSWTHGGGPGTADALPVRRTTATEWAWLLAAGAVSVAALTLLLGGVSDSTVPFPDALTTGLSLMATYGQCRKLLESWWLWIAADLVYIPLYAYKGLYLTSVLYVGFLALCVAGLLGWRRSLPAAGARTAVGAAA
>NZ_CP024985|6389494:6396563|6390111_6391428_+|WP_030240244.1|DBSCAN-SWA
MRSSGNGNGGGNRNSGGGGGGRGNSRGGSSSGGGYRGSSSPSPSGGGGNSRGGSSSGGGGYRGGSSSGGGGYRGGSSSGGSQGGGYDRDRDQAPQRPRNPRPEERRYDVGPEGERSGRSGPRAGGGGARGAAARGGAKGGPKTSKTPGIGGAGGPRRGPGSRSGQSRPRELDARIEERVRDRYADKPVIKTPKTFPGAEQEGERLQKVLARAGMGSRRACEELIEQARVEVNGEIVLEQGKRVQPKDEIKVDGLTVATQSFLFFALNKPAGVVSTMEDPDGRQCLGDYVTNRETRLFHVGRLDTETEGIILLTNHGELAHRLTHPKYGVKKTYVAAITGPLPRDIGKKLKDGIELEDGYARADHFRVVDQVGKNYLVEVTLHEGRKHIVRRMLAEAGFPVEKLVRTSFGPIELGDQKSGWLRRLTNTEVGMLMREVGL
>NZ_CP024985|6389494:6396563|6389494_6390112_+|WP_030240245.1|DBSCAN-SWA
MTAQELDLRGALEAVLMVVDEPATVEHLAKVLERAPREVASALAALADEYTAQRRGFELREVAGGWRFYTRPAYAAAVEAFVLDGQQARLTQAALETLAVVAYRQPVSRSRVSAVRGVNCDGVMRTLLQRGLVAEAGTEPETGAILYRTTNYFLERMGLRGLDELPELAPFLPEADAIEAETQEGVPSFDPDAPDTDEDDKTTEL
>NZ_CP024985|6389494:6396563|6395861_6396563_-|WP_030240229.1|DBSCAN-SWA
MDDLTLVRDHTIYACVMGSRAFGLATRASDTDRRGVFLAPTPLFWRFEKPPTHVEGPREEEFSWELERFCELALRANPNILECLHSPLVERLTPAGEELLSLRGAFLSRRAHTSFSRYAVSQHGKLLADVRLHGAPRWKHAMHLLRLLISCRDLLRTGRLTIDAGPDREGLLAVRRGERTWEEVDAWMARLTEETDAALTTTPLPAEPDLPRVADYLRRTRRASAALDPAPRG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_030240245.1|6389494_6390112_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	7.7e-09	30.1
WP_030240244.1|6390111_6391428_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_051841465.1|6391567_6392176_+	nicotinamide mononucleotide transporter	A0A0F6YPU8	Sinorhizobium_phage	4.6e-14	32.3
WP_030240238.1|6392172_6393261_+	AAA family ATPase	A0A2K8HHU5	Bacteriophage	5.1e-32	31.9
WP_051841467.1|6393374_6394064_+	NUDIX hydrolase	A0A0E3JJF3	Streptomyces_phage	1.4e-19	46.3
WP_030240233.1|6394072_6395101_+	ADP-ribosylglycohydrolase family protein	G3M9X5	Bacillus_virus	7.7e-06	28.3
WP_030240230.1|6395104_6395857_+	nucleotidyltransferase	K4K696	Caulobacter_phage	6.7e-07	39.3
WP_030240229.1|6395861_6396563_-	nucleotidyltransferase	A0A1J0GW18	Streptomyces_phage	1.5e-13	38.7

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP024985|8452510:8500516|DBSCAN-SWA
GATGGTGGATCATGTTTTCGTGATTCGTCGCCATGAACTGACTGATGTCGAGTGGGAGTTGCTGGCTCCGCTGATACCGAGTGCGGGCAGGGGCCGGCCTCGGGCGGAGGACCGTCGGGTGATCAACGGGATGGTCTACAAGATCCGGACCGGGGTTTCCTGGCGTGACCTGCCGGAACGTTACGGCCCGTGGAAGTCGGTCTACACGCGCTTCCGCCGCTATGCCATCGACGGTGTGTTCACCCGGGCACTGCAGCAGATCCAGGCCCAGGCCGACGCAGCCGGTGACATCGATTGGCTGGTCCAGATCGACTCCACCATTGTCCGCGCCCACCAGCACGCCGCCGCCACCGGCCGAAAAAGGGGGAAGCACCGGACGGACGAACCGGACGATCACGCCCTCGGCCGATCCCGAGGAGGCCTGACTGCCGAAATCCCTCTCGCCTGCGACGGCCGCGGTCGGCCCCTGGCCGTCCTGCTGACCCCGGGGCAACGGCATGACGGCGTCTGCGTGAGGCCTCTGCCCGGACGCATCCGAGTACCCCGCACCGGCCGGCCCCGCTGCCGACCGGACCACGTCATCGCCGACAAGGCCTACAGCTCACGCGGCTTCCGCGCCTACCTGCGACGACGCGGCATCGGACACACCATCCCGGAGAAGAACGACCAGAAGATGCACCGCCGCAACCGAGGCCGCCGAGGTGGCCGACCGACAGCATTCGACAGCAGGATCTACCGCCGCCGCAACACCGTCGAACGCTGCTTCAGCCAACTCAAAGGCTTCCGCGGCATCGCCACCCGCTACGAGAAAACCGCCACCTCCTACGAAGCAGCGGTCACACTCGCATCACTTCTGCTCTGGGCAAGATCAATTTGAAGACGGACCCTAGTTCGATCGGTGGCTTGCGCGGGTGGTGTGTGAGGGCAGCTGGTCCTGGCTTCCGGGGAAACCAGGACCGGTGTGGGGCCGGCTCGGGAACGGCCTCGCGAGGGATGCGCCCGTTTCAACGACGCCGGCTCAGTGCGGCAATGCCGCCATGCGGGGGAAAGCTGGGCGGGTCTTACCGGGGCAGGACGGCGCGTATGGTCTTGCCGCCGGACGGCCAGCGGGTGACCGTCGTGGCGCGGGCGAGGCGGTTGACCATGGGCCGGCCGAGACCCCCGGTGCCGCCGTTCAGATCGGGGGTGCGCATCCGCGGCGTCTGCGGGCTGGTGTCGTGGACGGCCACCTCGATGCTGTCCGGGTGCGCGGTCAGAGCCAGGGCGAAGGTGCCGCCTGCATGGCGCAGGGCGTTGGTGACGAGTTCCGAGACGACCAGGACCACCGTGTCGGCGGTCTCAGCTGCGGGCGGGCGTACGAGACGGTCGAGGAAGTCCCGGGTGCCCCCGCGGGCGCCGGCGACGGAGGCAGCGGAGCGAGCGGTTGCGAGGTTGACGCTCGTGGTGTCCATGAGGTTCACCCTGGTCTCTGGATCGGCAATGCCCGCTGGAGCCCGCGTGGTGCTTGCGCCTTGGGCTGTGGCGGGTAATCCAGTGACGGCCCCACGGCGCCTGTCCGGGTCGTTGTTCGAGGCCGATTACCTGATCGGCGAGCGCATGGAAATCTGTGTCGGCCGGAGTAGACATTGGGTGGTGGTGTGGTTATGGTTTCTCCCGTAGCCAAGAAGGACCGCAGGGCCTGGCAGAGACGAACTGCCGGGCAGCAGTACACGCAGTTGCAGTTCGCAGGACGGTGCGGTGACGGAGTTTCGAAGCCAGGGTTGTTGCAGGACGGCGACGGGACTGGTGACCGGACCGGGTGGCCCGCAGTGATCAGGGGCCGCCGTGAGCAGTACCGCAGTTGCAGTACCCGTAGTAGGTGCAGTTGGCAGTACCCAGCAGTGAGATCAGTGAGTGGTACCTCGGTGAAGGCGTCGGCTGCGGGCGCGCGCACCGGGAGGTTCGGCGGTGGGGTTCTAAGCCAGAGCAGATGCAGGATGGGCGACGGGGCTGGCTGCCGAAGTGGCGCTGTGAGAGGCCACCAGCAGTACAAAGCGGTTCGCAGTAGAGGCAGTACCAGCAGTTCGCAGTATCAGCAGTACGCAGTTCCCGTTTGGTAAGTGATTGATCCAGAGGGAAGAACGGAGGAGCCGAGCGCCATCAGGATCGCCCGGGCGAGCAGTACGGAGCCCGGGTACCGCAGGACATCGATAGTGAGGTGGTCTCCGGTCACGCATCCGCGATCCCCGCACCCCCGACAGCATCCAGGTCGGGTAGGCGGAAACAGAAGGCCGGCGCAGCATCAGGGCCGGCAGATGGTGTAGCAGTTCCTTCGGGGCCCGGGTGCCAGTACGGCACCCGGGCCCCTCCACGCGTTCCACAGAGAGCTGCAATGACAGCAGCGACACGTACGGCCGTCTCGATGACGACGACTACCCCGCCTACACCATGGGCCGGGCCGCAGAAATGCTCGGCACCACCCAAGGCTTCCTCCGCGCCATCGGAGAGGCCTGCCTCATCACCCCGCTCCGATCCGCCGGCGGACACCGCCGCTACTCCCGCTACCAGCTGCGCATCGCCGCCCGCGCCCGGGAACTCGTCGACCAGGGCACCCCCGTCGAGGCCGCCTGCCGCATCGTCATCCTCGAAGACCAGCTCGAAGAAGCCCAGCACCTCAACGTCGGATACCGCCGCGCCGCCGAATCAGCGAATCCGACGGCCGCAGCCTGAGCGCCTTCCGGCCTTCAGCGGATATGCGCGCAACTGGCCAAGCCGCGACGTGTACAGCTTTGCTGTGGTGACAGCATGTGCGGACGTGTACCGTCTGCGTCAGCTGTCGTGGTTCGGAAGTTCCCTTTGCCCACGCCTCGGCGTGGGCGTTTTGCTGTGCTGTGCCGCAGGAACCAGGGCGATCACCTCCGCTTTCCGCATGTCGTGGAAGGCGTTCATCGACTGGAAGGCATGAGACATGGCTACGGGAACTGTGAAGTGGTTCAACGCGGAGAAGGGCTTTGGCTTCATCGCCCAGGACGGCGGCGGCCCCGACGTCTTCGCCCACTATTCCGCGATCAACTCCTCGGGCTTCCGCGAGCTGCAGGAGGGCCAGGCCGTGACGTTCGACGTCACCCAGGGCCAGAAGGGCCCCCAGGCGGAGAACATCACCCCCGCCTGACCCCGGATACGGCAATGGCCGCACGGAGGACTCCGTGCGGCCATTGCCGGCAACCCCCCGCAGAGTCATCGGCTCACGCTCACCTGCTCGCCGCGATCGTCGAGCTTGGCGGGTGGCTGGAGCTCTCAGCTACCTGATAACGGGCGCTTCAGGGGCGCGGTCACCCCAGAAGGCTGCGCGGTCAGCGCCGCCTGCCGCCGATGCGGCGGTCGTCGGCGAGTGCGGTCAGCGGGCCGAACTCGCGGGCAAGCTGGTTCCACGTCAGAACCTCGCCACAGCGGGCCGGGAACTCCTTCGGGTTGAACTCGGGCATGGTCCAGGTGCCAGTGCCCCGGTCCCGCAGCCACAGGTCCCCTTCACCGTCGACCACAGTCGGCGGGACCGGTACGGGCTCGGCCTGATCGGTGGGCTCCCAGGTGACCCGGCCCGGGTGGGAAACGCGGCGCAGCTCGGTGGTGGCCAGCCGCGCGGCCAAGTCCCGGGTGGACTCTTCGGCGTCCTTGACCGACGCGAGTCGGAATGCGTCGTCAAGTACGGGCAGGGCTGGATTCTTGCTGCGCTTTGAACTCATACGGTAACTACCTCCGGTGGGGGGCGTCACATCCGTTATGGCACCCCGTAGTGGAACACGGTATCCGAGGCGGGAGTCGGGCCGGCTACGACCACTGTCCAGGTGGAGGGGCTGGCACACCGGGCGGTGGGGCTAGGTGGTGAGCTGGTCCTGGACGTGGCGCAACCCGTGGTGGTAGCGCTCAGATATGGCGGTCCGGGTCTGAGAAGGTGAGGCCGCCGGGGCGAGCGGACGTCGGGCCGGGGCGGGTGCCTTTCAGGTGCCGTGGTCCATTCGGTGTGTGCGGTGATGATGCGTCGTGCCCGTTCCGGCGGCCGGCCGAGCGGTCGACCGGGGAGGATCGGGCGGGCCGGAGGCCACCAGGCTTGTTCGGTGGGCCTGATCCACAGCTCGCCGATGGAGGCGTGGCGGGGCCGCGTGACCCTGTACGCGACGCCGTTGGCGATGTCCTCGGGGGCGAGGAACTCGACCACCCCGAGGAGAGGAGTAATCATCTCGTCCTGGATCACGGGCCTGTTGTGCAGGGCCAGTTCGGTGTGCACACCACCGGGCTCCAGGACACCGACGCGGACGTGCCGCTGGGTGACTTCCTGGCTCAGGGACTCGGCGAAGCCGTTCACCCCGAACTTGGTGAGGTTTTAGACGCCGAGGCCGTTCATCGCGACGCGGCCAGTGACACAGCTGATGTCGGCGACCCGGCGCGGCCCGTCCTCCGCGGCCTTGAGCAGGTGCGGGAGGGCGACGCGGGTGGTGTAGAGCAGGCCCTGGACATTAACGGCGATCATGCGCTCCCACTCCTCGGCGTCCGCGCCGACGACGGGACCCAGCAGCATCAGGCCGGGATTGTTCACCGGAGTGTCCAGCCGGCCGAAGCGCTCGACAGTCTGCTCCACTGCAGCCTCGGCTTGGATGCGGTCGGTGATGTCGGCTTCCACCACCGTCGCGGTGCCGCCAGCCTTCTCGATCTCGGCGGCGGTGCTGTCCAGACGGTCTCGCGCCGGGCCACCAGCGCCACGGCCGCACCGTGCCCGGCGAGCTGGCCTCCACGCGGCGACGGCCTGTCGCACAGCGGCCAGACCCAAGTTCGGTCTCTCGGGTTCGGAACCGCGGTGGGAGAGACAGTGATGGTCCGGTGCTGCACCGCCGAGCAGATGCGGCACTTCACGGACTCCGTCACCGAGATGGTCGATCGAGGCCGCGCGCTCAGACAGCTGTACGCCCACCAGGAGGAGCCCCCGCACCGCACCCGGTGCGCGAGGATGACCAGCGGGCGCATCAACCCCATCAGCCCCGCCTGCACCACGGGCGAGAGGCTGGCCGCTGAGCGCACCGTGATGCTGAGACCCCAGAGCACCCTGCTGCGGACGCTGGGCACCGACCGTGCGGTGCACTGCCGGTGGCAGTGCGGCGGTTGCTGGTAGTTGAAGGGCGCTCGTTGGCCTCGCGTCCCTGCCGGAGCGGCAGTGTCTGCTCCGGCAGGGGCGCTGGCATCATCGACCCGTGATGCGAGGCTTTCCGTAGTGTGTGGCCGGCTCAGTACCAGCCGATGATGTCCACGTCCATGCCAGGGTTCGGGCCGCTTCCCACAGGCTTGTCTGTGTCGTCGGTGAGTGTTTCGAAAGCGAGCTGCGGTTCGCCGGTTGCGCCGTTCGCCTTGAGGAACCAGCCGCTGCCGTTGTAGATCAGCGTCTTGGTTCCGTCTGGGCTGGTCGCCTGCCCGCCTCGCTCAGGGTGCACAGGGGCGGGCCGCTTGACGACCTTGCCGTCGGCTGTGAGGTCCCACAGGAGTTCGCTTCTGCCGCCGAAGAAACTTCCCTGGTCCAGGGTCGCTTCCTCGGTGAGCTGGTCGGGTGACGAGGGATCGGCCGAGTACACCTTCTCGTCATTGGCCAGGGCGAAGATCCTCTTGCCGTCAGCACTGAAGCGGGGCTGGCGGTAGGCGCGCTTACCGCCGTTGAAGGTGGGCTTGCCGCCGATCTTCACGCCTGGGGTCTCGTCGTACGCAGAGGTGATCGTAGAGCCGGTGAAGCTGCCCACGAACAGGTCGCCGTCCTTGACCCAGGCGTGCCGCTTCCAGTCCGGCGAGAAGCTGTAGCGCTTCCACGGGTTCTTCTCGGAGTACTGCGGCAGCGTCGTACTGAAGGTCTCCTTGCCCGTCGACGGATCGTAGAAGGCCAGCAGGGTGAGGTTGCCGCTGGTGAGTGAGCCGAGGCCCTTGGCGACTGGCGCGTCCAGCGTCTTCTTTCCGTCCGGCGTCGAGGTTGCCTGGGTGGACTGCGGCGCCTGTCCGGCTTGGGGATTGTCCGATGATCCTCCTGCGCCACAGGCGGTGGCACCCATGGCCAACAGCGATACCACGGCGGCGGAGCGCAGCCCCGTTCGCCACGGCACGCCCGGCTTGCTTAATGAAAACAACATTCACTTCCTCCGTCGTTTTGCGGCCTTGTCTCGCCGCTCGGCCCTTGGCAGGACCCTTGAGGGTGGATTCCGGCGCCTTCCCGCTCCAGGTGGCCGGATGCCTTTTCCGGCCGCAGAACGTCGTGGTGCCGATGGTGCGGACTGGAGCGGCGTTTCAGGCTGCCCTGCGTGTCTTTCGCGCCATGGGGGCGGGGAAACGCTTGCTGTGTCATGCGGTCACGGGGCCGGGGGGTAGCTCGGCGGTGGCGGATAGTGGGGCGTTCGATCGGGCCTGGACAGCGCCAGCCGCAGCAGGGCGGCGACAGCCCCAGGTCCCACGGCCATAGCCGCAAAGACGACGGGCATCCACCGAGGTGAGATCGCATCATTGTTCCTGTACGCCTCGGCGGCGTCGCTTGTCATGACCCCTGAGGGCCGCTCGTCATCCGATGCGTAGTCTCCCGTGTGCTGTACTCCGTAGTAGGCCGCGAACGCGACGGTCAGGATCGAGACGCACAGCACGATCCCGAGCCAAAGGCGTCGCGCGGACGGGTTCCGCATGGGGATCAGGGCAAGTAACAGCCACGGAACAGCTAGAAAGACAAGAGCGGTCAGAGCCATGTGTTCCCCAAATTCACTTAGTTGCAAGGGAGTTGCACAGTCCCCATACTGCGGTAGTTCTCGTCGTGATGCATCGCGATGGGACACCGCATGTGGAGCGGCAGGTGGGCTTCGCCGCGCGCACCTCCCGCCTCCCTGTGTGTGGACCCGCCGCTGAAGCTGGAGTTCATCGCGCGCAGGAGGTCCTCGATGAGCAGCAAGCGGAAGGTGGGGCCGGTTGAGTTCAGGGCGTGTTGCCGGTGGGGACTGCTTTGCCGTTCATGACCCACAGACCGAGGTTGTGCCATTTCTGGGTCTGCGGTTGAAAGAGCTTGTTCTCGACGGCCCGCTTGATGAGAACGCCGCCTGGGCGGCCGTCCGGGTACATGCCGACTGCGGAGATCTCCAGCTTCACGGGGACGGTACGGGGGCCCGAATAGACGGGGGTCACCTGGTAGCGCACGACCTGCCCGGCGTCCACGGCTTTCTTGACCTCGCCTTCCAGGGCCTTCATGTCGTTGGCGAATCCTTCGTCGCCCTTGACCTGGGCATTGGCGGCTCGGCTGCAGGTGACTAGATTGTCCAGATCTTCGCCACTGCCGGTGAGCTGCTTGCCGAGCAGGTGGCAATTGTTGATGCGCTGGGGAATGTCCTTTATGCGAAGGTAGCCGGCAGTGGCCGTTGCCCAGTTGTAGCCCGGAGGCCTGACCGCTGCCGTCGTCGGGCTGCCCCGCTGCGCGTGGGCCGTCAGGTAGGCCGTGTCGAGGCAGGCGTTCATGGCCGTGGCGCGGGATCCGTGTGCGACGTCGCGCGTACCGAGGTCGAGCCAGCCTGCGCCGTTTCGCCGGCAGTCAGCCCGGTCGGGCTTGTTCACCGTGAAATCGTCAGCCAGGTCCTTCGCGTTCCGGTCCAAGATTTCACGCGCCTGGACCACGACGTTGCGGGCGGCGACGACCTCGCTGCGAAACCTGGGAAGACCTACGGCCACCGTCTTGATGGCGTCTTGCACCTTGTCCGCCTTGCGAACGGCAGTGATGACGGTGCTGAAGTTGGCGGCCGCCAGCAGGCACGGCTTTATTTTTTCCTTTCCGGGTGCGCTGAGGCACTTTTCGATGTCCTTGACGCCGAGGAGTTCGAGGAGGATTCCCGCCCCGTTCTGCGCGAGCCATTCCATGAGCTTCGTGTCGGCCAGGATGCTGGCCTGACGGTATTGCCGAACATAGTCGTCACCGCGCAACTCCCGCAGGGTGTCCTCGTCCCTCACCGCCTGCAGGGCCTCGGACGGGCCGCCCCGGTACTGCCAGTTGTCTCCGCTGGTCCGTTCGAAGACCGCCGAGCGGTCGGGGGACAGGCCGTAGAGGTGTTCGCCGCTGACGGCGAAGGCGGCGCCGGGGGTGCCGATCTCGGTCCAGTGGTCGGGTGTGCCGTTGTACTGGTAGAGGTGGCCGGTGTCGGGGCGGGTGGCGAACAGACCGGCTCCGCCGGCGTACAGCTGATCGGCGGGTCCGCCGATCTTCGTCCAGTCGGTGCCTTGACCGCTCCATTCGAAGACCGCCGAGCGGTCGGGGGACAGGCCGTAGAGGTGTTCGTCGCTGACGGCGAAGGCGGCGCCGGGGGTGCCGATCTCGGTCCAGTGGTCGGGTGTGCCGTTGTACTGGTAGAGGTGGCCGGTGTCGGGGCGGGTGGCGAACAGACCGGCGCCGCCGGCGTACAGCTGATCGGCGGGTCCGCCGATCTTCGTCCAGTCGGTGCCTTGACCGCTCCATTCGAAGACCGCCGAGCGGTCGGAGGACAGGCGATAGAGGTGATCACCCGTAACCTCGAGATCGGCGGAGGCGTCTCCGATCTGACTCCAACGGCCGATTTCGCCGTCGTAGCGATAGATGGCGCCGGTATCAGGATGGCGAGCGAAGACTCCGAGCCGCCCTGCGTGCACGGACTCTGCGGGTCCGCCGATCTTCGTCCAGTGGTTGTCACCCTCGTGCTTCCATACGCTGCCGTGATCAGGCGCGAGCGCGTAGAGATCGCCCTTGGCTGTCACGGACAGTTCAGGACCGGCGATGTCAGATAGAGCCCCCCGTACGGAGCTTGGAGATCCCGCTTCCGGCACGGATTCAGCCTCTGCTCCGTCCTGCGCTTCTGACCCCATTCCCGGCGGCGCAGACTGCGGCTCCGGGCTGGGGTCCGCCGCTTGAGGCACCGGCGCGCCGGGGGCCGATGGCGCGCCGAGGGCCGTCCAGTCCGCGCCCTGGCCGCTCCATCGGTGGACGCTGTTGCCATCGGATGCGAGACCGTAGAGGCGAGTGCTGCCGACGGCGAACGCCTTGCCCGCGTTTCCGATCTCGGTCCAGGTATCGGCCCGCCTGTCGTATTTGTGGAGTTTGTCGTCGGGGCTGGTGGCGAAGAGCCCTGCTCCGCCGGCGTGGAGATCTTGGGCGGGTCCGCCGACTTTGGTCCAGTCGGTGCCCTTCCCGTTCCATTCGTAGACGGCGGTGCGGTCGGGGTTCAGGCCGTAGAGGTGGTCGCTGGTGACGGCGAAGTCGGCGCCCGCCCCGCCGATCTCGCTCCAGGTGTCCGGCTGCCCGTTGTACTTGTGCAGCTTGCCGTCGGGGCTGGTGGCGAAGAGCCCTGCTCCGCCGGCTTCGAGGTCTTGGGCGGGTCCGCCGATCCTGGTCCAGTCGGTGCCGGTGCCGTTCCATTCGTAGACGGCGCTGCGGTCGGGGTTCAGGCCGTAGAGGTGGTCGCCGGTGACGGCGAAGTCGGCGCCCGCCCCGCCGATCTGAGACCAGTCGCCGGGCTGCCCGTTGTACTTGTTCAGTGCTCCGCTGCCGAGGCTGGTGGCGAAGAGTCCCGCTCCGCCGACGTAGAGGTCTTGGGCGGGTCCGCCGACCTTGGTCCAGTCGGTGCCCTTTCCGTTCCAGCGGTAGACGGCAGTGTGGTCGGCGGCGAGCGCGTACAGCTGGTCGTCAGCGGTCGCCGTCACCGACACCAGGGTGATGGGGGCGGCCGGGGCGGGGTCCGCGGAGGCGGGGGCGGCCGAGAGCAGGCCGGCCGTGATCGCGCCGGCGAGCAGGACACCGATGCGCCGCAGGCGCGCCGGTGGCGTGCCGGGTCCGGGCTTCGTTCGGTTACGGGAAAGGAGGTGGGCCACAGGAGACGCTCCAGGGAATTTGTCTGGGAAGTGCTGGAGCCCCACGGTCCGACCTGGTCTGATTGTCCATCAATAGATGTTGTCCGTTAACGCAGTTCAGGCGACACGGAAGAGCGGACAACGCGGACAACCAACCGGGGGAGTGCCGCTGTGGTGAAGGCCGGCCGTCCACAGGGCGGGCCCAAGGGGGAAACCGATGAAGCCAACGAGCTCGCGGTGTTCCTGCGAGATCTGACCCAGGACTTCACGGTCCGCGAGCTCGCGGAGCGGTACAAGATCAGCAAGACGAGCTGGGGCGAGTACCGCTCCGGGACCAAGACGATCCACCTGCACCTGCTCAAACGCCTCGTGCATGACCTGGTGCGAGATGAGCGAGCGCGCGCCGCGAGATGGGCGCTGGCCCAGCGCCTCCACGAGCAGGCAACCACCGCACAGCAGCCTCTTGGCCCTGACGAGCCGAACACCGCCATGGAGGGAGTGACGGCGGCACAGGCGGCAGCGCAGGCAACTGCGGCTCTGCAGGACGCGGAGCGCCTGGTCCACATCCTCCTCGGCGTCATCGCCGGCCTCCAGATGCCCTCACAACACGGCACGGCACCGGGCGCCGACGCGGCTGGACTGGCTTCCGCCGCCGATCAGGCAGCCACTGATCTACGTGAAGCACACCACCGACTGGACCAAGTCCGCCTGGTCCAAGACGCTGTACGCCGCGTGCGTGACGAAGCCACCGCACACGACGACCCATCCGGCGCAGCAGATGCCGCATCCCGTGCCGACGACGCCGGCCGGAGCGGTAACGATGAACATCTTCCTGTGCCCTACACGGCAGCCTCACGCGAAGCCTCCGCCATCCTGATCGTCTCCCGCGCCGCACTGGTTGAGCAGTACGCCGCAGCCCGGCTACTCAGCGCCCGGGCAGCGGGTGTGCACGCCATCGAGCCGACAGCTGTACAGAACACCCCCCGCGGAGCTCTGGCCCTCACCTCCCCGCCCCGCAGCCCCACCGCGGTCTCGCCACCCTCTGACCGGTCGCGCCGCCGACGCCAGATCGTCATGATGGCCGTTGCCGTGACGCTCGCCGCCTCCCTCTCAGCGGTGGCCGCCGTCACCCTCGTGCGAAACGGGCAGCACCCCCCCCTGGAACAGGCGAACCGGCCCACACCGGCCCCTGCGGCTTCCCTGCCGCCCCCGACATTGAGCCCTTCACCTCCGGCATCGCCCACGCCGTCCCCGAGCCCGGACCTGATCGACCCAACTTCGCCCCCGAACCCGACCCGCTCGACTGAGACCAGTGTGACGGCGGTCCCCGACGACTACCTGGGCACATGGCAAGGCGAATTCACCAAGCCCGGAGACAAAGCCCCTACCTTGCGCCGCATCGAGATCCGCAAGGGCGCGGTGGGCGCAGAGACCGCGGACATCCTGACGTCGACCGCCAGCTCCCTCTGCCAGTCAAAAGGAACCCTCATCTCGGCCGGCACACTGCTCGTCCTCACAACAAACCCGACCTCAGGAATCCCCAGCCATCTCTGCACCACCAACGCAGACATCACCCTCCGACGCCAAGGAGACACCGACCTCACCTGGAAATCAGAAGGAACCACAGCCACCCTCCACCGCACCGCGCCACAAAACCAGACGATCCCCGCCCCCTTCATCGGAACATGGCGCGCCCAGGACGGAAACGACACCACCTCATCCGTGCGCATGACAATCAACCAAGGAACACCCGGCCACGCCCGGGCCGAATTCGTCTGGGACGGCGACGCCCACCATTGCGAAGGCTTCTCCGTACTTGCTTCCATCGGCGACGCTCTGACCTTCAGCCCCGAGACGGTCACGTCGTCCGAACCACAGCGCTTTTGCACCCAGACCCCCACCCGCCTTGTCACGCAATCCCAGGGCAACACCCTCCACGTGGAATGGGCGGATGACGGCGGTTTCTTCCGCTCATTCACCTTCCACCGTGTCGGCTGATCCAACCCACGGCGGACAAGGCAGAAGGCCCCGGATCCTTGAGGATCCGGGGCCTTCTCATTTCAGTAGCGGGGACAGGATTTGAACCTGCGACCTCTGGGTTATGAGCCCAGCGAGCTACCGAGCTGCTCCACCCCGCGTCGGTGAACCCCACCTTACGGCACCGCCGGACCGCTCCTGACGAGCTATGACTTGCGCAGGCGTCCTGCGGCGCCAACGATGAGGGGGTCGGGGCGGCCCACCACCGCTTCGTCCTTCCCGTCGTAGTCGATGTGCCACTGAGGCTGCGGATCGCCTCCAGCCAGCCGCGCCGCGTGTCGCTGCTGATCACCACCGTCCATGGCGCGGCGCCGGTGTCGGTCGGCGCACCTTCACCGCGGCTTCCTCGACCGAGTCGGCGGTGGCGAGGTTGGTCACCTCCGACGCGCCGGGGTGGTCCGGCTCGGTGCACCTGGCGAGGATCCGGCAGAGCCCTCGCTGCTCCGGCGGCCGTACACCGCCCGATGCGGGGTGCGCCTGTCCGCGCTCCTCCGGATCGCCCGCACGTGTGTACCCGCATCCGAATGCCTGCTGGCTCACTCGGCTGAACGGGGGAGCGGGCCTTCCTTTGATTCAGCGCCCGGACGCTTTGGTGTCCCCGTTTTGGCAGGTCTGCGGTTCTGCACTCACTGTGCCGGCCCGCCGGGGGCGGTATCGGGGTCTGTGCGGGTGGTTGTGGGAGGCGTGGGGCGGGTCGGGCGTGTGCGTGAACGCCGGATCGGGTGGGATGGGCAGGGCGCCGCGTCGGCTTCTTCCCCTTTAGGGTGCTGTCGGCCGGGCACCGGCCGCCGTCACACGTCGCCGTCACGCAGCCACGGCCGACGGCACCTGCTAGACCGGCCCGCTGGCTCTGTGGGCGTGCGGGGCCGTTTTAGAGTGGCGTGGGTGCAATCCCCATGGGGCGGCTCTATAGCGGGGAAGATGTGCGCTGGGGGCCATCCTGCATGGGCGCGCCGGGTGTCTGTTGGTCGCGACAGGGATGGATCGGTTGGCATCGGTGAAGACTCTCCGCATGCCTGAGGACCCCGATGAGCTTGTCGACGCCATTGCTGTCGCCGTGCGGGCGGGCGATGACCGCCGTATTGGCCTTCTTCTCGACCGGTTCAAGGAAGTGGCGGGCCTTTCCCACCTGATACGGCTGCGTGAGCGGCTGTGCGGTGCGGGCGGGGCCGCGAGGGTGAGCGCCCGCGGCATCTGGTGGAGCGCGACGAGGACGTGGTGAGGGTGGGCCGGCGCTGACCGCAGACACGGCGAGAAGAGCCAACGGCGGCCTGATCACGGTGGCGGTCATGGCAGCCAGGGGCTGTTCCAGTCGTCGATCTCCTCCCGCGCGAGGGAAGATTTCGGCGTGTCGCGGGTCTGCTCCGTGCGGCGGGGGAGCGGGCGGCTGGCGGCGAGAGAGGTGAGGACGTTGTGCCAGGTGCCGTCCGTCTGCCACAGGCGCAGACGTTCGGCGCAGCGGTGCCAGGGCCCGTAGCGGGCGGGCAGGTCGTGCCAGCGCCGGCCGCCTCGCTGCTGCCACAGGATGCCGTTGACGACGGCCCGGTAATCCGGCCCGCCCGGCCCGCAGCGCGGCAACAGCGCGCGGATCACGGCCCATTCCCCGTCGTCGAGGTCGTCGCATTCGCTCACACCATGACAACGGCTCTCCCCGCGGACCGACACGCCCCAGTCAGCGTGGGTGGACGTTTCTGCTGCGCGCTCGCGACTGGGTCGGTCGCTGGGCAAGGGGCTGCAGAAGGCGCGGGTCATGCCTCTTGAACCTGCTCAAGCTCAACTGAACCGGACACTGCGGACACGCATCAGGGGTGACTGCGGCAGCCCGGCAGCCCCCAAGGTCCAAGGGGGCGGGGGCGGGGTGGGCGCGCTCTGCCAAGGCTTCTGACGGCGCGCTGCGCTGTCCCGCGGTCGGGCCGGGCTACCACTGGTCCGTGGCGGATCCCTCTACGGGCCGAGTCCGGGAGATGGCCGAGCGCTGCCCCAGCTGCGACTTCCGGCCGGGCAATCGCGGCCAGCTTGCCCCCGGCCAGTTGGCCGCCCTAGTCCGGGACTGCCTTGGCGGACGAGGGGCAAAACGACCAGCCGGGCGCGATCCGCGCACCCAGACGCCGGCCGCTCCCTCGCACTACGGCTGTGTGTCAGGTGCCGGTGCCGCAGTAGGACTGTTCGGGCGTCCAGTTCGCGGGGATGATGTTGATGTAGGTGGTGGTCACACCGAGTTCGTTCGTCAAGCGCAGACTGAACGGGGCCCGCAGTGGACGGTTGCTGTCAAGCCGGAAGACGTCGCCCCACGTCTCGCGCATCCGCGTCCAGGTGGTACTCCCCTGCTCCCGCAGTTCGAGCCCGGCGACCCCGACCACGTCGAGCAGGGGCCGGACCGCGAAAAAGGTCGCGTTGCTGCCGATTTCGACGTGGAAGCAGTCCAGAGCCGGGGTTTCCCCGGCCTTTGGAGCCACTTGCGGCACGGCACCCCCGGCGGGCGTCGCATGCGCGGCCGGCCCCGCAGCCACCATCGTGATCGCGGCAGCGACCCCGACGCCCGCCACAGCCAAACGGAGTGCCGAACGAGCCCAGCGCGGACCCTCATATCGCCTCGATCGCTCCATGAAAGCTCCTGGATCAGTCGGAAGACGAGAGGCACGGATCGGCTCTCTCACCGAGAACTTCACTTCCGATTCCCGCACCCGCAACCTCACCAGCCACCGGAGTGATGACCCAGCGTCACCGACACGGGGCTGCAGACCCCCTGGGGCAAGACGAAGGCCCCCGGGGGGGGCCCCTATCTCTTTGGTCAGGTGGATGGGTGCTGGTTCGGGCGTCTGGGACGATGTGCCTGTGCATGCTGACGTCGTGTGCCCGGGTGACCGGACGTGAGCGGATGGGGGAGTACCTCGGACACGGTCTCGCGTGCCGCCGCTGCGCCGTCCCCGGTGACCGCCGGACCCTGTACGGCATTGTCCAGTGCCTCCATTTTGGAATGAAGGGCCCCGGGCTCCCCGGCTGTGTCGGTGTCGACCAGGCCGTCGCCTTCCTCCTTGCCGGGCCGGGCGTCGCCGTGCCAGAGGCCGGACCCGCGGCCGTGGTGCCCGCCGCGCGGTCCGCCCTCGCCCCGAATCCCGATCCGTACGCGGCGCCTGCCGCACCAGAAGCCGCCTCTGGTCCTGCTCCTGCTCCCGTTCCTGATCCGGCCCCGTCCCCGGGGCCGGCCCCGGGGACGGTGGCGGGCGGACGCCCGCGCGATGTGGGAGCCGGCTGACCGAGAGGTTGAGCGTTCCCAACGATCTGGACCTGTCCGACCGGCCTGCCGCCCTTCAACAGCTAGGCGTCGGCGCGGCGACGAACAGCCGGCTGGTGACCAGTGCGCAGGACTGGATCGGCCCTGAGCGGGAGACGGCCCTTGTTGGTCAGTACCCGGGCCTGGCCCCTGTTCGCGGCCCGCATGGCCGACGTCGCCCGCGGCCCCGAAGGCGAGCAGGGCCTGCGCGACCGGCTGAAGCCGGGCTGCTGGACAGAACTGCGAAGGGAGAGGTGTCCGCCTCGGCTGGGCCCCAGGACTCGCGGATCTCGGTGCTGCGGTCCAGGGGGCTGCTGTACGGCGGGCTCGCGGAGGGGCGGGCGGCGAAAGGGGTGCTGCTCTGGACCCCGACCAGTACATTCTTGTATCTACTCGATTACAGAAAGTTGTTATCGTCTTCAGGGGGAGAGAAATCGTCCCGCCTGTGGCGGGGGTGCGCCGAAGTCGCTGCGGTAGGCGAGGGCTTCGGTGCCGGGGGATCGAGGGGGCTGTATGAGCTGGATCGGCAGTTGGTGAGCCTGTGACCATGAGGGCCGCGATCCTCACTGTGGCGGGCTCGATCATCGTGGGGTGTCTGGGACTGTGGTCTGGCGTGTTCAGCGGCAAGGACGACCGCGACGATCCGAAACCCGCCCCTTCGGCATCACAGGCAGGTCCTTCCTCCGGCGGTGCCGGCCCGGGACAGGTCCTGCCCGCTTGCGGCGGCAAGCCGGGACTGGATGTGACCGTCGAGCCCAAGCAGCTGACGGTCGCATCGGACGGGTCCCTCACCGCTGAAGTCAACTGCACCCTCGGGGCCGGATTGCATCTGAGCTGGATAGTGCAGATCGACGGCGTTGGCAAGCCCGTGCCGCACACGAACTACTATCACAAGGATGATCTGGGGCGGCCCGGCCCGTACACCTTCGATGTCCACCTGTCCCAGGCCGTGCCCGGTTCTGCCCGCACGATCTACGTCGTTCTCACGGACGACTTTTCCTACCGACAGCTGAGCGACAACCGGAACCCGGACGGATCGCTCCTGAAACTCCCGAACGGTGCACGCAAGGTCTCCAACTCGGTTCTGGTCAAGCGCTACTGACCTGCCCCGGCACAGCAGCGAGGTTCGGCCATTGATCGGCTCGACGGCATATCCGTAGGCCGACGGAATCCTGCACGCCCCATGGAGCCCGAGGTGGCCGTGGCTAGGCAGTGTCTGATGGCTCTTTGGTGAGGTCGCGGAGCCAGATCACGATGGCTGCGGTGGCCAGGGTGCCGTGGAAGATGTAGTCGCGTTTGTCGTACCGAGTCGCGACGGCCCGGTGCTGTTTCAGCTTGCTGATGCAGCGTTCGACGGTGTTGCGCCGGCGGTACTGCTCACGGTCGAAGGCCGGTGGGCGGCCGCCGGCCCGACCAAGGCGGCGGCGGTTCGCACGCTGGTCGTCCGGCTGGGCGATGGTTGCTTTGATCCCGCGTTTGCGCAGGTAGACGCGGTTGGCGCGGCTTGAGTAGGCCTTGTCGCCGCGGGCCCGGTCCGGCCGGGTCCGCGGACGTCCTGGCCCGGTGCGGGCCACGTTCAGGGCCTGCATGAGCGGGATGAACATCGGGCTGTCCCCACGCTGACCGGGCGAGGTCAGCCAGGCCAGGGGCCGGCAGCGGTCATCCGTCAGCAGGTGGACCTTGCTGGTCAGCCCGCCCCGGGAGCGTCCCAGGGCCTCACGGCCATCTCCGTCCACACGCGCGCCACCCCCTTTTCAGGATGGTCGGCCGGAGGAGCGTGCCGGGCTCCGGCTGCGTGCTGGTGGGCCCGGCAGGTGGTGGAGTCGGCGTTGACTGCCCACGAGCCGTCCGCGTCCTGGGCGGTGGAGTCGGCGCTGGCCTGCAGAGCGCGCAGGATCTTCGACCAGGTGCCGTCGGCCGACCACCGGCGGTGGCGTTCGTAGACCGTCTGCCAGGTTCCGTAGCGTTCAGGCAGGTCACGCCACGGAATCCCTGTCCGCGTCCGGTAGAACACACCGTTGACCACGGTACGGTGATCAGCCCACCGCCCACCTGGGTTCCCGGTCTCCGGCAGCAGCGGAGCTATGCGCTCCCACTGAGCATTCGTCAGTTCATGCCGACGCACCATGCCAGACCCCTGCCCAGAACAGTGATAGATCCACCATCCCAGGCAAGAGCCATCAGACACTGCCTAGAGCCGGCTATTGCCGCGTCTGTCCGTCTGTTGCCCTGGTCCGTCCTGGCTGAGGGCATCCTCCGGACGGTGGATGTTGTCGGCACGCAGGCCGGCGCTGTCGTGGGTGAGGTCGAAGAGGACTCTGTCGCCGGGTCGCAGACAGGGGCCCTTTCCGTGGATGGCCCGGGCTTCGGCCCGGATGTCCGGTCCGGTCCCGTCCTGGCTGATGAGACCGGTACCCCGGTCAGGGTCGAACCACTTCACGACTCCGCAGGGTGACATGCTCTGCCCTTTCATTGGCCGGATCTGGAAGCCGATACTGTCCGCCTGCTCTCGGACGGAGGGGAGGGCGTGATCAGGGGCGCGATGCAGCGGACTCCGGCGTGGCTGCAGCCGGCGGGCGCCCCTTGCGCGGTGGGCTGCGGGGGCATGCCAGCACCGCCCGCCTGCCCGGGAGCAGACGGGCGGTGCTGGCGATCCGCCTGGTTCCGCGCTGGTGGGCCATGGCTCCGGCGTACTTTCGACCGGCTGACGGCCGGGGGCTCGTCCGCTGCGGCATCCGGACTCTTTGCCGGTGGACGGTACGGGGATGCGAGAAGATGGAGAGCTGCGGCGGGGGAGTGGCCGGTGTCAGCGGCGGGCGTCAACTCTCGCCTCCGCTTGTCACGCGGGATGCCGAACGCAGTGCTTGTGATGCCGGGTGGTGGCCGGGTGTGGTTATGGTCGGTTCAGTCCGCGTCGACAGGGCGTGCGCGGGCGAGGCCCGGTGACCAGAGCGCTCTGGTGGCAGTAGCACCGGGCCGCCCAACCACCCCGAGGACGAAGGTCCCGGCTACGCACGCGCGGCCTGTGGGTGCGGCCGCCCGCCCGGCGGGGCCGAGCGGCAGGCCGGGCACTCCTGTGGCTCGCCCCGGACTGCCCCACCACCGTCGTCTACAAACCCTCCCCTGAACAGGCGGTCTAGCGGTACAGACCCCCGCTCCGACAGGCCCTCGGCGGACAACTCACTCGTGCGGGCGGTGGGATTCACTGCAGAAACGCGCCTGCTTCCTCCGCCTCGGCAGGGTCGAGGTAGCCGCCCTCACCGGCCCCCCTGCCGACGTCCGCGTGGACGTTAGGGCAGGTCATCGTCGCATGGGGGCAGCAGATGTTGTGCCACAGCTCGTGCCACGGCACGGGTGGGTTCGTTGAGTGAGGCGAAGACCGTCTCAGGTTCCTCCGAGCCGCTCGCGCGAAGTGCGTACAGGCACGCCCGGGTGTTGACCACCTCGGGGAGGTCCGGGTGCTCGGCCTCCGAACGACCCCAGTCGTAGAGCCCGGTCGCCGACCCGTTGTCCGCAGGAAGAGGACGTCCCAGGAGTCCCGCGAGGTAGTGGTGGTCGCTGTCGTCGAGGCTGTCTGTACGGGAGCGCTCCTGGAGCGGCTGGCGATAGGAGTTGAGGTCGTGCTCGGCGCGTCCGTTCTCGCGGTAGACCTGCGTGACCACCCGGGTGATCTGGGACAGGGTGTCGATGGCGTCGCCCAAGCGGTAGAGGACCATCCGCGGGACGTTGAAGGGATTGCCGTTTTTGGCTGTACTCCAAGGCATCGGTCAGGTCTCGGACGGCTTCGTAGGCGCTCGCGTTGAGTCCCGCGACCAAGCCCGCGGGCATGGTTGTTTCATCCCTGTCGGAGTGTCCGCTCGCGTTCCTGGAGGCAGCCTCCAGTCGCTGAGCCGTCGTGTACCGCACACCGGCCGCCTGCTGCATCGCACGCGCGGCCGCCTTGCGCTTCTTGTCCTGCGTCATGGTCTTCCTCACGCCGCATGCCCACGCCCATGCCGCAGTAAGGCCGGCAACGGCTTGAACGACTGAACGCGAGTCCGGGACCCTTGTCCGTGTCCGGGGCGTGGGAGCTGATCCGGGCGGAATTCTGGCAGGCGTGGGCTGCCGCCCCAGCAGAGTAGCGGATCGACTTGCCCCGGCTGTTGCTGCAGCCACGAACTTGCATCCTTTCGCGGGCCGTGTCGTACGAATGGGTTGTTCGCGTTGCAGCGAACCTCAAGCTTTCCAGCGTGTGTCCGCTTCGCGCCGCCGCGACCGCCGCGCTTTCGTCTCGGATACCAGCGCGAGTTCCGAAGGGTGTCTCTGCGCTCACTGTGGAAACGGAGGATTGGTCAGTTCGGACGTCGCCCTCGGCGAGCCGGCATCTCGGGGCCGGTCCCCTGGCGCAGCACCGAGCAGCACGGCGGGCAGCGATGGCCGCAGTGGTGCCGGCCACGCACCACGCCGGGGAGCCAGGGTGAGACGACCCACCCGTATCGGGTCCCCGTGGCCTCCACCGTTGACCGTCCCGCACCGTTGTGAAAGGAGGGGGCGTGCTGGTCTATGCGCCGAGGGCGTCCAGCTCCTTGCGGGCCTCCTTCACGAAGACGTTGCGCAGCCGGGTCAGCTCCCTCTTGTCGGCAGCCAGGATCTGCTGCTGCTCGTCCCGGTCGAGCTGCGCGGTGAACACGAGCGAGCTGGCCTGCGTTTCCCTGAACCCGGCAGCAAGAAGGGTTTGACGCGCCCGTTCTCCGGCATCCTGGACACCCTGCGCACGCTCGACCGCCGCCAAGGCTTCGAGGGCATCACTGGCTGCTCTGCATCTCTCGAAGCGCTCCCGCATGTCCTCGTACTCTTCGGGTGATCCCGGCGAATCGACCATGTCGTCCCCGTCCGGCCCGGGTACAAGCTCAGCCAGTAGCCCACGGGTATCGGCGATGCCCGACCCCTGTGTCACGTCCGACCTCAGCCGCTGCTTGGCAAGTTCCAGCTGCTCCATGTCCCTGGCCTGCATACGCAGGGTGAACAGCATGAGGTCGACTTCGATTGCCTTGTTCCTCGCTCGGCTCGCTTGCTCCAAGACGACGGGCGGACTCATCAGCTCCACCATGGCGTAGGCCTTCAACAAGTCGGCCACCTCCGACTCGTGGCTCGTTGCCTGTTCCTTCGCCTTCAGCAGGTCAAGCTCCGCGACGAACGCGGCCCAGATATCCTCGCACCGGTCGCGCTGCCACTGGGCGTGAGCTTCGCGGGACATCTCCCGGACTCCCTCCAAAGTGGCCTGTGCCTGGAGCCGCCCGGTCTCAAGCGTCGCCTGGGCTTGGGCCTGCGCGGCCTCAAGTGCTTTCGCAGCCTGCTCATGTGCGGCCCGCAGGGCGGCCTCGGCCTGCGCCTGCGCCCCCTGCAATGCCCGCTTGCCCTGAATGGCTCCCGCGACGATGACGCCGGGAACCGCCAGCAAGGCCGCTCCCCCAGCCACGACCGAGCCGAAGTCCTCGGATATGAAGCTGCTGATGTCCATTTACCCCCCATGTGGTGCCACGACCTGGAGAGCCGACGGTGGCCCCAGGTGGTGCGGGTGGTCGAGGGGGCCGTGGCAATACGCGGACCCGGCACTTTTACGACGCTGGCTTCGACACCGGAGACGAAGCCGTAGGCGTCGTCTGCCCAGGGCCGCTCCCCCCCGCTCCGAGAAGCGCGCCCGCACGGAGCCGTAGGCGGGGCGGGTGCCGGCGGGTGTCGTCCGTGGTGAGGCGGGGTGGGGCTGTGGGCGAGGAGGTTGAGGGCGCCCGATGCTGGGCACGGGACTCGCAGGGGCAGGCTGTGGGCCGCGCTGTAGCCGGCGGCCAGGGCGAGGGGGGGCGAAGGTGGGCCAGTTGTCCTCGTGCGCGGTCAGGTCGCCGGCGTGGACCGGATCACCGGTGGTGTAGGCGTCGATGCAGGGGCCTTCGTCGGCCTGGGCTGGAACATCTCGGTGATCTCCACCCCCGCTCCTCGTGATGCCATGGGCACGTCGGGTATAGCTTTCGGCGCTGCCGGCACAGGCCCGTGCCTACGGCCCTTGCCGGCTGTGCCCCGCTGCGCCTGCCTGGTGCCCACGCCAGTAGGGCATCTAGTATGCGGGACCATGACGCCAGTGATCGCCTCACTGCCCAGCGGAGTGCCCGCGGAGCTCGGCGGCTACAGGATTCTGGGAATCCTGGGCGCAGGCGGCATGGGGACGGTATATCTGGCCAAGGGCCACGGCCGGCGGGCGGCTCTGAAGACGATCCGTCCCGAGTTGCTGAACGACCAGGCGCTGCGAGACCGCTTTGCCCGGGAAGTGGCCGCCGCGGCCTCGGTGCGCGGTCGTTATGTGGCTGCCGTGCTTCGTTCCGCGCCTTTGGCCGCAGTGCCATGGCTGGCTTCGGAGTTCGTCGCGGCGTCCACCCTCGAACAGGCCGTACGCCGTCACGGGCCGCTGTCCGTGCCCGCGGTGTGCGCCCTGGCCGGAGCGCTGGGGCGAGCGCTGACGGCGCTGGAATCAGCGGGCGTCGTCCACCGGGACCTCAAGCCGTCCAATGTATTGATGGCCCTGAACCGCCCTAGAGTGGTTGATTTCGGTATCGCGCGCATGGCAGGGGACCACACCCTCACCAGCGCCGGACAGCGTCCAGGGACAGCGGGATACATGTCACCGGAGCAGGTGATGCAGGAACAGCTCGGACCGGCCAGCGACGTGTTCTGCGCCGGAGCGCTGCTCGTCTTCGCCGCGACGGGACGGCACGCGTTCTACAACGGTGATCAGGCCGGAGCCGACTTCCGGATCGTCCACGAGGAACCCGATCTCAAAGACGTACCGGGCACCTTGGCCCGGGTGGTACGCGGCTGCATGGAGAAACGGCCTGCCGATCGGCCCACCGCCTCAGAGATCGCGGCCGAACTGGACCCGAGAGGGGTCGGCGCGGGCGCGGCGAAACGCTGGCTCCCGCCCAGCGTCGTCGCCGACGCCGCGGAGATCGAACGAGCCGCGACCGCGCTGGCCGGCCGCGCCGGGCTGATCACTCGGCGCAACGTGTTGTCGGCAGGGGCGGCCACCGTCGTCCTCGGGGGCGCGTCCGTAGGGGCTCTGGTCTGGGGCCGGTCTTCTTCGGAGTCGCCGTCCGGGCACGATCCCGCGCCCCGCTGGTCCGGTGAGCCCGGCGAGGTGCCGCCGGTGCTGTGGTCGCTTGAAGGCGCGGCGGTCACGCCACGCTATCCGCCGGGGGACATCGGCGGCGCGGCGTACTTCGAGGAGCGCGGCGGCGGGCTCGCCGCCTACGACATCGTCTCGGGCCGACGGCGTTGGCGCGGCCCCGCCGTACGAGAGGTGCTGGGCGGGAGCCGTCCCGTCGCGCTGGACACCGACGGGGCCGTGTTGTTCCTGGCCGCGGCCAGCGGTGCGGTTCTCAAGAGGATCAAGGCAGACGCCGACCGTCTGCTGGCGGTCGACCGTGAAACCGTGTACGTCCTGGACCATTCGGGCGAGATACGCGCCTTGCGGTCGGCTGACGGTACCCAGCGCTGGCACGGCAAGCTGCCCGTACCCGGCCCGGTCGCGGCGGCCGGCGGGCACGGTCTGGTGACCGTGGTGTCCGCCACGGGGGCCGTGGTAGCCCTGTCCGCGGCGGACGGTGCACGGATGTGGCGCTATGACATCAGCGGCGCCGACAGGCCGGCGCCCGACACCGAAGCGTGCCGGCCCGCCATGTCCAGCGAGGCCGTGGTGCTGGGGGGCGGAGCCGCGCTCACCGCCCTGGCGCCGAGAGGGGGAGGCCGCCTGTGGCAGCTGGCCGCCGACGAGCGAGCGGGCTTCGGGGAGCCGACGGCGACGGGCGACAAGCTGTACGTGCGGGACGGGGCTCAGCTCAGGGCCGTCGACGCGGTGACGGGCAAGGCGGCCTGGACGGTGGCCGCGGGCGCCGAACTCGCCCCGCGCCCGGGGCCGCTGGTGGCTGGCGCCAGCGTCCACGCCGCCCTCGCCAATCCCGAACTGGGCGTCCTTGCCGTGCATACCGGACGGGCAGCGGCCCAGTACGTGTTCGCTCCGGCGATCGCCTCCGCGGCCCCCTGGCAGGGGGCCGCGGTCGCAGGCAGGGTGGTCTGGCAGCGCGGTTCGAGCGTCAGTGCGATTCCGGCCATGTGAAACGGCCCCGTGAGGGCCGCCGATGAGGGGGACGGGTAATGGAGAGGCTGCTCGACGGCGACCCGAGGTCCGTCGGACCGTACCGGGTGCTCGCCCGATGGCCGAGCCCGGGAGCGGCGCGCTCCGGGCCTGAGCCGAGAGCGGAACAGGGGCCCGCCGCACGCGGTCGCCCATCCCGGCCCGCCACATCGCCGGCCATGTACCTGGGCCGTGACCGCGCGCATGTTCACGCCCTGATCTGCATGCTTCCTCGCGCCGCATGCGCGGCGGCCGAGCTCCTGGCCGGCGTTTCGGTGCCAGGCGTTCCCGAGGTACTGGAGCTTCACACCGCGGACGAGCCGCCGTGGGCCTCCCTGGCCCACATACCTGCCGTCACCCTCGCCGCCGTCGCCGGCTCCACGACCGGAACACTCGAACCGCAGCCGGCGGACCGCATCCGTGCACTGGGCGGCGCACTCTGCGAGACCCTGGCCGGTCTGCACCAGCAGGGTGTCAGCTACGGCGCATTGGTCCCCTCGGGTGTCTGGCTCACGACGGGGCGCCCTCTGCTGATGGCCTTGTCCTCCTGCCGGACAAGCCCGACTGCCGAACGGGGGCGGCGCGACGAGGAGATCGTTCCCCCGTCGGCCCTGCCAGCCCCTTTCATGGCACCTGAGACAGTCGGCGGCCGGGTGTCGTCGCAGGCCGCCGACATCTACGCCCTGGGCGTGCTGCTGGCGCACGCGACGACGGGACGGTTTCCGTTCGGTGAAGGTCCACCTGAGGTCCTGGCCTACCGGGCGTCCCATGGGAAGGCCGAGTTACACGGGCTCCCGGCGGATCTCGCGGAAGCCGTGGCCGCCGCTCTGGCCCCCGTGCCGGGCGACCGTCCCACCGCAGCCGAGCTGTCGCAGACGTCCGCTCTCACAAGGACGACCCCGGTGGCGGACGGTCCCGCCCCCGGGAAGGTGATCATCGCACTCGCGGCCCAGGCGCAGGAGACGGCGGATCTCGGGGAGGGCGCGGACCGCGATCTCCCGCGCCGGACGGATGTCGCGACTCGGCCCCTCCACCGTGCCGCGGACGGTCCGACGCGCTCCTCCGCCACCGGACAGACTTCCCCAGCTGGCCCGCTCACACGGCGAGCGCTCCTGTCCCGGCTGGCCACGGGCGTGGCGGGCGCCGTACTGGGCGCGGGTACGTCCCTTGCCTGGACGGCGACCCGGGAGCCGGCCGACCGGTCCTTACCGGACCGCCCCCTCGCGACGGCCCCGCTGCCAGGACTGCCGCCCACCGCACTCTGGCGCTTCGACGACGTGACCGCGAGGACCACCCTGCTACGGGTGGCGGGTGCCGGGCGCTACCTCGTCACCCGGGGCGAGACCCTCCATGCCCATGAGGTCCGCAGCGGAAAGGAAGTCTGGGAGCGGCCGATCGCCTTCGGCCGTGCCAACCCTGTACTCCTCGTCGGCGGGGGCCGCATCCTGGTGCAGACCCGCGACGCCCTCGTGCTGTGCTCGCTGGGCGACGGCCGGACGCACTGGATCGACCGAACGTTCCACACACAGAACACGACCGTCCTGGAATTACTCGCAGTCGAAGGCGACACCGTCTGGCTGCACATGGGTCCTGCCGCCGGCGCCTCCGCCACGACCCACGCCCTCGCCGCGTTCGATCTTGCGGCGCGCAGGGAGCTCTGGCGCAGCGAGTTGCCCGCGGACTTCGTTTACGAGCTGTCCCTCACGCCCACGCCGGCCGGGCTCCTCGTGGAAGTGCTCCCCGAAGTCGACCCCCACCGGGATCCCTATGGGACGCGCAAAGTGCCCCTGGCCTGCTTCGACCGCACCACCGGCAGGTCCCTCTGGCAGCGCACGTACGAGGGCGTGTACAGCGGTCCGGCCTCCGCCGTTGACGAAACGGGCCGGTTCTACGTCCTCTCCACCGGCCGGGCCCGCGCGTACGACGCCACCCCCGGGAGTCAGTTGTGGGAGTCCACCCTGCGCTTCGGCGGCCAGCACAGCCCGCTCCTGCTGACCGGCACCCTGCTGTGCGAGACGGATCCGGTCAACGGAGTCGTCGCCCTGGACAGGGACACCGGACGCACGGTGTGGCAGCAACGGCTGGACGAGCCCCTTCAGTGGTTCCTGCTGGGGACCATGGCGACGAGTGCTTCGGGCCGCACCCTGTTCGTCCCCACCAGACGGCAGCTTGCGGCGCTGGACCTGCGGTCGGGTGAACGGCTGTGGCAGATGGCCTTCGTCGGCCGGGAGGACCCCAGCCCCCTCCAGCTGTTGGCGACGCCGGACGTCCTGATCGTCGCCCAGCCGAGTGTGGTCTTCGCCCTGCCGGCTGTCTAGCGATGGCAGCCCCCAAGGAAAGTGATGGTGCCCCGTGCCCTTGGTTCTCCCCCTCCTCCCCGACGATCCCGCTCGGGTGGGCACCTACACGCTGATGGGCCGCGTCGGCGGTGGCGGCATGGGGACGGTCTATCTGGCACGGACGGGAAGCGGCCGCCTGGCCGCCGTGAAGACCGTCCGCACCGAACTCAAGGACAGGCCGGGCTTCCGTGACCGTCTCCTGCTCGAAGCGGAAGCCGTACGGCTGCTCGGCTCCTCCCACACGGCCGCGTTCCTCGCGGTGGACGCCGAGGCCTCCCTTCCCTGGCTGGCGACGGGGTACCTCATCGGACCGTCGTTGTCGGAGGCGGTCGCCGTCGCCGGCCCCCTGCCGGTCGCGGCCGTGGTCATGCTCGGTGCAGCAGTGGCGGACACCCTGACCACCCTGCACCGTGCCGGGCTCGTCCACCGCGACCTCAAGCCGGCCAACCTGCTGATATCTGCCCAGGGCCCGAAGCTGATCGACTTCGGTCTGGCCCGGGCGCTCGGCGGCCCTCCGCTCACCGCGGCGGGCGAGCCGGCCGGCACGCCCTCGTACATGTCACCGGAGCTGGTCCGAGGGGAGGAACACGGTCCGCCGGGGGACGTCTTCGCGTTGGCCGCCGTGCTGGTGTTCGCATCCTCGGGGCACGGTCCGTACGACGGAGGGCCGGGCCGCGACGCCTTGCGGCTGCTGCGCGACGGGGCGCCCCCGGAACTGACGGGGGTGCCGGACACGTTGCGGGAGGTGATCCGGTCCGCTCTGTCACCCGATCCCCGAGACCGCCCCACCCTCGACGAGCTGGCTGCGCACTGGGGCCCCTACGAGGCCGCCCGGTTCTCCGAGTCGCTACCGGGTGAGGTCCTCGCCGACATGTCGCGGCGCGTGGACGAACTGGCGTCGCTGGGCGGGACGCCCCTACGGGAGGATTCCCCGCCCCTGCGCCCCTCGTACCCCTCCCGTCGCGTGCTGCTCGCCGGCGCCGCGGCCGTGGCGGCCGGCGGCGCTTCGGCACTGTGGTTGACGGGCAGGTCACCGGGCTTCGGAGGGGGATCGGGGGCGCCGGGGCCGGTACCGTCCCCGAGCGGCGGTCTTCCCGGCGGCTCTCCCCGTCAGCAGTGGTCGGTTCCCGTGTCCGCCGTCTACGGTCCGCCGGTCGCCACCGAGGAACTGGTCCTCCTCCCCGGGGAGACGGTACGCGGCCTGTCGCCGACGAGCGGCGGCATGCTCTGGGAGGTGCCGAGCACGAGGCTGCGGGTCGCCGCCTCGGGCCGCCGCCTCGCCGCCCTCGCCTTCGACGAGGAGCTCACGCCTGCAGCGGGGTATCTCGACCCGCTCTCCGGCCGCCTCATGCCGGACGCGGCCGGCCCACACGAACTGGGCGCTCTGAGCCTGTACAGCGAGGTTCTGAACGCCGACGCGGACACCCTCTACATCAGGGCCTACTACGAGGCCGACAAGGACCGTGCGGAACCATGGCTGCTGGCCTACGACTTGGCCGCGCACCGGCTGCGCTGGCGTACCCGCGTCGCATGGGGATACACCGATCGGACGGAGGCGCTGTACTTCCGCGCCGTCGTCGCGAACGGGCGCCTGATCGGCTCCGACGCCACCCGCGTCTTCGCGGTCGACGTTCGTGACGGCCGCTTCCTGTGGGTCACCAGGTTGCGCAGCGACGCGGAAGCAGCCGCTCCGGGGGCATCCGGAGGCGTCTATCCGCCGGTCGTCTCGGAACACCACGTCTTCGACGTCAGCCAGGTCATCACAGCTGTCGACCTGCTGACCGGCGCCCCCACCTGGACGCTCAAACCCGAACGCGATCAGACCCTGTTGACCTCCCCGGTGTGCGTACAGGGCACCGTCCACATCGCCTCGCATGCCTTCACGGCGTTCGAGGAGTCGACCGGCAGGAAACTCTGGACCTACGAGCCCGGCCCCTCCTTCCAGCGAATCGCCGTCCCGGGGCCCTTTCGAGGCGAACTGTACGCGGCGGTCAGCGGCGGGGGTCAGGCGGTCGTCGCGGTGGACCTGGCACAGCGCCGCGCCTCGTGGACCCTGTCGGCACAGGCGGCCGGCATGCCCGACGGGCCCAGTGACCTGACCCACCGGGACGACCGGCTCTACTTGCAGGCATACCAACGCCTTACGGCGGTGCGGATCGACACGCGCCGGTGATCGAACGGTTGGCGGGCCGGCTTTCCGGCCCGCTTCCGGACGGGCTCGCAGCCTTCATGCCTGCTGTTAGGACTGGACGCCCGCCCATCCGCCGTCGGTTCCGGCTCTTGCCCAGCCACGACGGCGACAGCACGCCGCATGGAGTCGGTTACTGAGGTTGAAGGCGTGATGTCGGGGCCTGGTGCTCCCGCCATGGGGGAAAGTCGGTAGGTTACCTGTCATGGCTGAGCTTGGACCCGTTGTCTGGCCGCCCGCCCCGTTGCGGACCGAGCGGCTCGTGCTCCGCGAGCCCGAGGCCCGAGACCGTGCGGCGTTCGTTGACCTGTTCGCTTCGTCAGAGGTGCGGACGTACCTCGGTGGCCCCCGACCGCGTGCTGAGCTTGAGAATGCAGTGCCTGAAGTGCCCGGGCGGCGCCCAGGCGTATTCGTGGTCGATCACGACGGGGCGATGATCGGCATCGTCACGCTTGACCGGCGGGGCGCGGAGCGTCCGGGGCACGTCCGTCCTGATGCCGGGGAGGCCGAGCTCAGCTACATGCTCCTGCCGGAGGCGTGGGGACGTGGGTACGCTCTTGAGGCATGTTCGGCGGCGCTCGGCTGGTTCGCCGACGTGTTTCCCGGTGAGCCGGTGGTGCTCTGCACCCAGGTGGCCAACGACCGCTCGGTACGTGTCGCGGAGAAACTGGGGTTCACCGAGATGGAGCGGTTCGAGGAGTTCGACGCCGAGCAGTGGTTCGGCGTGTGGTCCTCGGTCCCGTGGTCTGGCTGAGCGCGTACTCGGCCAATGAGCGGGGTTCCAGATCCGGTTCCTTGAGCGCGGCTTCACAGGAGCGCATGCTGCGGCGGCTCGCAGTATGGCCCGTCGGAGCCGGACCTGAGGATGAGGCCGGTAGCGGTGAGGCATCCGTTGATGATGTCGCTGCGGTATTGGATCTGGCGGAGACCGTGTCGGAGTCGGCGCATGAGGTGGCTCGGGTCGGTGAAAGCGGTGTTGGCCTGGCTGGTGCGGCGGAGGATTGACCAGATGCCTTCCACGGGGTTGAGGTCGGGTGCGTAGGACGGCAGGTGGTAGGCGGTGAGCCAGTCCTGCGCGTCAATGAAGGCCTTCATTCGGCGCTCTTTGTGGACGTTCAAGTTGTCCCAGATGAGGATGATTGGTCCGCCGAGTTGCTGGTGGGCGGCGATGAGGAGGTCGCGGTACTCGGTCCAGGCGAAGCACTTGCGGCCTCCGCTTTTGTGATCGGTATGCCGTTTGAGCCGGTAGATGAGGCGGGAGCGTTCGCCGGGTTTGTGGCAGCACAGGGCGGCGCTGGAGAAGCGGCGCTGGGAGCGTCCGCGGACCCGGATGACGGGTGTGGTGCCGCGTCGGCTCCAGGTGCGTGAGGTCGGCGGCGTCATCGAGAATCCGGCTTCGTCTTCGAAGACGATCCAGACTTCGAGCGCCGCCGCGGTGTTTCCACGTGCGGCCACACGTCCTTCACCCAGCCGTCCACCGCCGCCTCGTCACGCTCGACGGCCCGACGGGCCGGCACCTGGTGGCTCCAGCCGTGCCGCCGCAGCATCTGGGAGATGCCCGACAGCGTCATGGACTTGTGGAACCTGCGGCCGATCAGGGTTTTGATCCTGGCCAGCGTCCACCGCTGGTCCGGCCAGCCGTGCGCGACCGGGCCCTTGGCAAGCTCCTCCTCAAGCACGGCGAACAGCGCGTCGCTCAGCTTGGGACGACACGCCGGGCCGCGGGAACGGACCGCGTCCTGACCGGCCGCACTCCAGGCCTGCCGCCACCGCTGGACCGACCGGACGCTGACCCGTAACTCCTTCGCGACCTCGCCACTGCCCCGCCCGACGGCGAACATCGCGACCGCTTCCATCCGGACCCGCTCGCGGAATGCTTGCCTCTCCGCGGTCAGACCCCCACCCTGCGGATACCTCATACATCCGGCATACCGCGACGATCAGCAACCGTCAGCCCCTACGACAACCCGACTTCAAAGTCAGTATCTTCCAGCCCGCCCAAGCACATGAGAAGCGCCATTAACCTGCATCTCGCACCTCTCGAAGGAACGAGAGGCCCCGCCGGTGTGGTTGTGGTCCTCGAAGACCGGCGCCGCCCCGGCGGACGTGGACCTGTGGTGGCAGGTGTTCCTCAGGAGATTCGATCTGGAGCACACGTTCCGTTTCGGGAAACAGACGCTCGGCTGGACCACCCCGAAGGTTCGTACTCCCGAGGCGGCGGACCGCTGGACCTGGGTCCTGGTCGTCGCCCACACCCAACTTCGCCTCGCCCGGCCGCTGGCCACCGATCTGCGCCGGCCCTGGGAGAAGCCGGCCAAGCCCGACAGCCTCACCCCGGCCCGGGTCCGCCGCGGGTTCAGGAACATCCGCGCCCACCTGCTCTGCCCGGCCCGTGTTCCTCAACCGACCGGAACCGGGCCCGGACGCCCCCTCGGCTCGAAGAACCGGCGACCCGCCACCCGCTACGACGTCGGCAAAACCGTCAAACGCCCCGAGACCCTCAAAGCCATCGGTAAACCTGGCAGATCTTGGTAGATAAAGAACAAGCTTAGGTAGCACCCTCTACGGCGCCCTATGCCTCCGGGGGGTCTGTCAATCGAACGGTGTAACGAGGGTGGTTGGGGTTACTGCCGGGCTGCGGAGAGTCGGCCGTCGAAGGTGCTGTCGAAGGCGTTCAGTGCGGTCTTCCAGCGCATGGTCCAGCGGGCCTGACCTCGGCCGGTGGGGTCCAGGGACATGATCGCCATGTAGACGCACTTCAGGGCGGCGGTCTCGTTCGGGAAGTGCCCGCGGGCCTTGACCGCCCGCCGGATGCGGGCGTTCACTGACTCGATCGCGTTGGTGGAGCTTTGCGATCTTGTCCCAGTCCTGCCGGGCGGCATAGCGGAAGGAGTTCCGCAGCAGATGGACCACGCAGGTCTGGACGGTCGTGCGGGGCCAGACCGTCTCGACGGCGTCCGGCAGGCCCTTCAGGCCGTCGCAGACGAGCATGAGGACGTCGTTCACACCGCGGTTCTTGATCTCGGTGAGGATGTGCATCCAGTGCTTGGCCCCCTCACCGCCGTCGCCGGCCCACAGACCCAGGATGTCCCGCCGGCCCTCGACAGTGACGGCCAGGGCGACGTAGATCGGCCGGTTCGCGCCGGCGCCGTCGCGGATCTTCACGTGGATCGCGTCGATGAAGACCACCGGATAGACCGGGTCCAGGGGCCGGTTCTGCCACTCGGCCATCCCGTCCATGACCTTGTCGGTAATGGTCGAAATCGTCTGGCGGGAGACTTCGGCGCCATAGACCTCGGCCAGGTGGGCCTGGACCTCGCCGGTCGTCAGACCCTTCGCGGACAGCGAGATCACCGTCTCGTCCACCCCGGACAGGCGCTTCTGCCGCTTCTTGACGATCCTCGGCTCAAACGATCCGTCACGGTCCCGGGGCACGGATATCTCCACCGGACCGACGTCCGTCAGCACGGTCTTGCCTCGTGTTCCGTTACGGGAGTTGCCGCCGTTCTTCCCGGCCGGATCGTGCTTGTCATAGCCGAGGTGGTCGGTGATCTCGCCCTCCAGGGCGGACTCCAGCAGCCGCTTCGTCAGCTGCTGCAGCAGACCGCCCTCACCGGCCAGCTGCAAGCCCTCAGCCTGAGCCCGGGACACCAACTCGTCGATCAGCCGGTCATCCACCGCCTTCGACGGCTTCGGCTCAGACGGCTCGACGGTCTCGGCCTCGGTCACGTTCTCACTGGTCATCGATGCATCTTCCTTGATCGGGAGTTACATCGAACGATTTACAGTCCCACTGGCACCCGGGTTCCCTCGCCAGAGCGAATCCACCGAGGGGTGCAGAGCATCAGGAGCGTCACCGGCGGAAACTGCTCACGGACCCGGTGGCGTACGCCGAATCCGGCGGCACAGTGATGTAACAGCCGCACCTGAATTGGGACCCTGATGGCAGCGGCAGTACTAGCGTGGGGCGACAGGACTTCCTGGAGGACGATCATGAGCGCTCAGCCTGAGCACACGCCCATCCCGTCGTATGCGCCCTCGCCCGGTGCCCCGGCTGAACTCCTCGCCCAGCTGCGTGCCGACCGGCGTGCGCCGCAGTGGGTGCCGGCCTTCGAGCGGGAGTGGACGGCAGCGCTGGAGGAGTCGCGCCGGACGTTCTCCCTCGCCGGTCTGTACGAGGTCGTCCAGGACTGGCAGGGCCGCCTCGCCCATGCCCCGGCGGTCGACGCGTTCGTCGCCTCCGGCTACGACGACGGCGAGACGATTGACATGGCAGAGCTGCGGGGAAGGCGCCGGTGACCGGGCAACCGCACGCGGTCCGCTTCTCCGCGCCGGCTGCGAAGGTTCTCGACACCCTGCCCGAGCACGCAGAGGACACCGTGTGGGACGTCTTGGACGCCGCCGCGGTCAACCCATGGGGGTTCGGGCAGTGGAACGCCGACGACCCTGAAGGCGAGGACGTGCGCTACGCGTCGGTCGGCAGGCTGTCCCTCACCTACTGGGTCAACAGACCCCTGCACCGCCTGACCGTGCTGAACATCGTTTGGCTCGGATAGCCACCCGGTGACAACGCCTCGGCGCGGGCATCGCAACTGTCGGGGCTGGAGCGTTCTCCATCGTAGGCACGGCTTTATCAGCCGTGCCCTGCACGGCACCGTCCTGTAATGGCGATCTGCTCGTCCACGGCCGCCGCGCGCCTGCTGGCCGAGTCCCGGCTGACGGTCGTTACTCGTTCCCTGCCGGTGGCAGAGCGCCTGAGCGGGGCGGGCCGGGAGCTGGGTGACGTGGCTCCAGCCGCGGCCGTCAGTCGCCGTGTGCTTGGGAAGACCTGCCGGGGTTCCGGGTGGGGGCCGGGACCCCGGCAGGCCGGTCAAGGCCGCGGCGGCCGTAGTGGCATCAGTTGACGGTCCACTGCTGGAGCGTGGTGCCGGTGTCGGGCTGCTGGGTGACCAGTGCGCCATTGGCGGAGGAGGCGGTGGTCAGGAGCAGTCCGCTCCAGGCGGAGGCGACGGTGTGGGTGCCGTTCGCCTGTCGCGTGATGTTCCAGCGCTGGTTGGCGCCGTTGCTGCAGGTCCACTGGACGATCTTCGCGCCGGGGCTGGTGGAGCCTCCTTCGACGTCGGCGCAGAGGCCGGACTCGCTGTTCTTGAGCTGGTACGTGCCATCGGTCTGTTGAGTGAACGTCCAGCTCTGGTTGGCACCGCCGTTGGGTGACCAGGTGATGAGCTGGGTGCCGGGGGTAGTGCTGTGGCCTGGGTTGTCGAGTGCCTTGCCCCCGGCGGTGAGGGTGTGGACTCCGTCGAGGGAGGCTGTGACCGCCCAGGTGAACGTGGCCGTGCCCCCGGCGGTGCCGGAGGCTGCGGTGACCGTCACGGTCGAGGCGCCGGCGGCGGTGGGAGTGCCGGTGATCAGGCCGCTGGAGCTGATGCTCAACCCGGTCGGCAGGCCGGTCGCCGTGAAGGTCAGGGGCTTGCCGAGGGAGTCGGTTGCCACGGCCTGGAGGGAGACGGCCTTGTTCACGGTGCCGGCCTGGTTGCCCGGGTTGGTGACCATCACCGTTTCGGGGACTTGGGCGATCGGGATCAGTGTCAGGGTCTGCTCGCCGGCCGTGCGGGTGCCGCCGACCGCGTTGCCGGTGGTGTTGGTCCAGCTGCGGGTGGGGGTGGTTTCGGCAAGGCGGGTGGAGTCCGCGGAGAGGCCGATGACGAGGCCGCTGTACCGATTGACGATCTTGTACGTGCCGGTGGAGGCGCCATCGGCGGGCGAGGTGCCGCGTATGACGAACCACTGCTGGCCGACCGTGGGTCCGCCGGTTCCCGCCGCGGTGACGGTGGGCTTGGTGCCCCAGGCGCGGGTCGCCGTCGAGGCAGCGCCCACCCCGAGGAGCTGACCGGTGCCGGAGTTGGCGATGCGGTACGAGCCGTCGCCGTTCGAGGCGAAAGTCCACGACTCGAGGCCGGAGCCGGTGGCGGCGGCGCTCGACGTGGTGGCCGAGCTGCCGGAAACCTGGGCCAGGACCCGGCCGCCCGCGCTGCCGATGCGGTAGGCCTTGGAGGTGTCGACCGGCGCGGCGGGCTCGGTCGTGTCGATCGCGAGGTTGACGTACTCGCTACTGGCTCCGTTGGAGCAGCCGAAGGAGCAGTACGAGCGGAAGTTCTTGCCCACGATGGTGGAGCTGGTCTTGTTGCCGCTGTCGAGGAACCAGCGGTACCAGGAGGCGTTCTTGTAGCTGCCCGTGTCGCCGAGACGGAACCACTTCTGGGTGGTCAAGTCAGCGGTGGCGTAGATCTCCTGGGAGGCGTTGCCGCTCTGGTCGACCGCCTGGGGCTGGCCGATGTACAGGCCGAGGTGGGCGTTGTAGGTGATGTCCATGACGAACAGCGGGGACGTCGGGGGCATCAGGCCGGCGGCGACCTGCTGGCTCACGGAGCCGCTGTTGGCCGGGTCGTACTCCTTCGACGGCGGGGTGTATCCGGTCGCGCTGCCGGAGCCGACGGGCACCATGTTGCTCTCGCGGCCGCCCAGGCCGGGCTCGGACCAGGCGCCGTCGTACCACTTCTGCCAGGAGCCGGGCGCCAGCTTCGCCGATATCGGAGCGCGGGCGACGTGCCCGTAGAACGCGGCCCAGCCGCCGCCCTTGTTCACGATCCGGGAGCCGTAGAAGGCGTAGAAGTAACCGGACCCGGTGTCGACGAACAGCCGCTGGTCACCGGTGCCGTAGTGGAAGGTCTGCTGCGGGAAGGCGGCGTCGTCCCCGCGCTCGGTGCTGTAGTGCGAGGTGATGACGTGGTCCTTGATGGTCCACGTGCGGCCCTGGTCCTTGGAGACCGCGTAGTCGATGCCGTCGTAGTGCAGGCCGTCGGTGAACGGCTGTGGGGTGAACTCGTTGTGCACGAGTCCGTACCAGTCGCCGGTGTCCGGGTCGACCCAGACGCCGGCGAGGTCACAGTAGTTCCGGTGTGCGTAGCTCGAACCCGCCGGGGCGGGTGTCGCTTCGAGCCCGGTGGGGCTGTTGTTGCAGCGCCAGGTGGTGTCGTTGTTGCGGTCGTTGGAGTTGGCCGGGTTGACCGCGTCGCTGATGGCGACGGACCGGGTGGCGGTGTCCAGGTTCGTCCCGGTGAAGAACGTCCACTTGCGGGGATCGTCGGCGCCGTAGAGCGCGTGGGCCTGCTGGAAGTAGAACGTGCCGTCCTTGTCGACGTAGGTGCCGGCGGGGGTGTCGTCAGGGTGTGTCCAGGAGCCCTTGGCGCCAACGGTGACGGAGTAGGTGGCGGGGGCGGGGACAGGGGCGGTCGACGCTGCGGATGCCGAGGGCATCATCAGCGTGCTGCCGCCGGAGATGACCAGCGCGGCGGCGGCGAGTGCGCCGGCCAGTCTGCTTCGAGGAGTGATCACGGGTACTCCCTGATGGGAGGAGCCTAGTGGGGCGGCTCCCTTGACGGTCCGTCGTCCTTGGGGACGGCGGTTGTGCTCGGGACTGCTGCGAGGCGGCCCGAGTGGGGTGCTCCGCGCCCCGGGGCAGGACGACACGGGGCGCGGAGCAGTGTGGGGGGCGGGTCCTCAGACGCCCGCCAGAACGTTCAGGAGGCGCGCGACTTCCGCCGCGACCTCCTCACGGGCCGGGCCGAGGTACTTGCGGGAGTCGCTGACCGCGGGCTGACGGTGGAGTTCCCGCCGGACGGTCGCGGAGAAGATGCCGTTGAGGTGGGTGGAGATGTTGACCTTCGTCATCCCCGCCGACACGGCTTTGGCGAGGTCCGCGTCCGAGACGCCCGACGAACCGTGGAGGACCAGCGGCACGCGGGTGGCGCTGCGCAGCCGCGCGATCAGGTCGAAGTCCAGTACGGCGTCGCGAGTGGCCATCGCGTGGGAGCTGCCGACCGCCACTGCCAGGCAGTCCACCGCGGTCGCCGCGGCGAACTCCCGGGCCTCCGCGGGGTCGGTGCGGACACCGGGGGCGTGGGCGCCGTTCTTGCCGCCTACCTCGCCCAGCTCCGCCTCGACGAGAACGTCGGCCCGGTGCCCGTACTCGGTGACCGCCCGGGTGGCCGCGACGTTCTGCCCGTACGGCAGCTTGGAGGCGTCGAACATCACGGAGGTGAAGCCGAGCCGAACGGCTTCGTGCACCAGGTCCTCGGACTCGGCGTGGTCCAGATGCACGGCCACGGGCACCGTCGCCTGCTCGGCCAGGGCGAGTGCGGCGCGGCCGATCGGTGCGAGGGAGCCGTGGTAGCGGATGGTGTTCTCGCTGATCTGGAGGATCACGGGCAGGTTCGCCCGGTGTGCTCCGTCCACGATGGCCTCGGCGTGCTCGAGCTGGACGACGTTGAACGCTCCGACCCCCCGGTTCAGGGCGTACGCGGGGCCGATGATGTCGTCAGTGGCTGTCAGCGGCATGGGGCCTCTCCACACTCACGGTTGCGGTCGTACGGAACTGGTCGTAGAGGTCGCGGCGGAAGTCGCCCGCGAGGGGTGCCGAGACGGCGGCCGCGGACAGCGCGACGGCGTCCCGCAGGAGGTCCGGCCAGGGCAGGCCCGTCGCGAGACCGGCTGCGAGCGCGGCGACGCAGGCGTCACCCGCGCCGGTCGGGTTGCCGCGCAGCTGGGCGGGCGGAAGGGTGCGGTAGCGCCCCTCCGGGGTGACGGCGTGCAGGCCCTGGGGGCCGTCGGAGGCGACGACCGTCCGAGCGCCGCGCGCCTGGAGTTCCGCGGCCGCGTCGGCGACATCGGACCGTCCGGTGACTTCGCGGATCTCCGCCGCGTTCGGCTTGATCACGTCCGGGCCGGCGTCCAGCGCGGCGAGCAGGGCGGCGCCGCTGGTGTCGAGGACGGTCACGGCCCCGGCGTCACGGGCCGTCGCCAGCAGTCCGGCGTAACTGTCGCACGGCAGACCCGGCGGGAGGCTGCCGGCAAGAACGACGACGTCGGCCCGGGCGGCGAGTTCGGCGAACCGCCGTGTGAAGGCCCGCCATGACTGCGGGTCGACGTGCGGCCCGGGCGGGTTGAACACGGTGGCGTCCCCGTTGCGTTCGGAGACGACGGTGATGGTCTTGCGGGATTCACCCCGTACGGGGACCAGTGCGTCCTTGAGGCCGGACGCCCGCAGGTCCTCGCGGAGGATCCGGCCGGTCGTCCCTCCCACCAGACCCGTGGCGAGCACCGGGTGGCGCAGTGCCGCCAGGACCCGCGTCACGTTGATGCCCTTGCCGCCGGCCCGCTCGACGGGCTGCGTGACGCGGTGGGAGGCATGGGGGGTCACCTCGTCGACGAAGTAGGTGACGTCCAGGGCGGCGTTCAGGGTGACCGTGAGGATCACAGTGCTCCTCCGGCCGGGTCGGCCACCAGCTCGACCGGCCTGCCGGCCGCTGGGTCGGCGTCGGCGGCTTCCCAGCCGAGCAGGCCGGCTCCGAGGCAGCCGGCCTGCTCCCCGAGAGCCGCCCGGACCAGCTTCGGTCGCCGGTGACAGCTCAGGCGGCGGTCGAGCGCGATGCGCAGGGGGTCGATCAGGAGGCCGCCGGCCTGGGACAGGCCCCCGCCGACCACGATCACTTCCGGAGCGAGGACCGCGGCGCACGCGGCGAATGCTTCCGCCAGCGCCTCGACGGCGCGCTCCCACACACGGCACGCCACCGGATCGGCACGCGCCACGAGAGCCGCGACCTCCTCGGCCCCCTCGACCTCATGCCCAGACCGGGCGGCGTAGACGGCGGCGATCGCGCGGGCCGAGGCCACCGCCTCCAGGCAGCCCCTCATGCCGCACGCGCACTGCTCGGCTCCGGGGGCGACCGTCAGGTGTCCGATTTCTCCGGCGTATCCGCACGCACGGAGCGGACGGCCTTCGACCAGGAGGGCGGCGGAGATTCCCGTGCCGATGGCCACGAAGAGGGCGTCGTCGAAGCCGCGGGCTGCGCCGAGCCTGCTCTCCGCCGTGCCGCCGGCGCGGACGTCGTGGCCGATCCGGACCGGGAGTCCCGTCGCGTCCGTGAGTACCGCGGCCAGGGGCAGGTCGTACCAGCCGAGGTTGACCGAGTGCACCGCGCGCTGCGTGGGCTCGTCGACGATGCCCGGGACCACGATGCCCGCGGCGACGGGTTCCACGCCGATGCCGACCGCCGCCCCCGCCAGGTCGCGCAGCAACCAGGTGATCGCGTCCACCGTGGCTTCATGGCCTTGGCGCCGCGGGGTCGAGCTGCGCAGGGTCGCCAGCGGCCGCATGGTGCGGTCGAGGAGCGCGCCCTTCATCGACGTGCCGCCGACGTCCAGAGCGATCACGCAGGTGCGGCTGCCGGCATGCTCAGGCATGCGCGCCGGCCAGCACCACGGAGCGGCTCAGAGCACGGGGCCGGTCCGGGTCGAGCCCCCGTGCGCCGGCCAGGTGGACGGCCAGGCGCTGGGCTCGTACGAGGTCGGACAGCGGGTCCAGATCGCCGGCCGCGTCGCCGGATTCGGCGACGTAGGCGACGCCGGTACGGGCGACGTCGTCCGCGAGGCCGTGCGGTGCGGGGCCGAAGACCCAGGTGCCGCGGCCGGGGCGGGCGATGCTGATGGGGCCGTGGCGGTACTCCATCGCCGGGTATGCCTCCGTCCAGGCGCCGGCCGCCTCCCGCATCTTCAGCCCCGCCTCCAGCGCAAGGCCGTAGGCCCAGCCATCGCCCAGGAAGGTGATCTGCTCCGCTGCGCACATCACCTCGGGCAGCGGTGCGGCCACGGCCCGTTCGGCGTCCGCGGCGGCCTGCGCGATCGTACGCACTCCCCGGGGCAGCGGGCCGCCGCTCTCCAGGTGGGCACGCAGAAGGACGAATGTCGTCGTGGCGAACCTGGTCTGCACGACCGACTTCTCGTCGGCGTAGGCGAGTTCGATGACGCCGTCGGCAACGTCGGCCACCGGGGTGCCTGCGTCGGCGGTGACGGCGGTGACCGGCGCCTGCCCGCGCAGCCTGGCCAGGAGGTCCAGGACTTCGGTGGTGGTGCCCGAGCGGGTCAGCGCCACGATGCGGTCGTAGCGGCGGCCCGCGGGGAACCGGGAGGCGGCGAAGGAGTCCGTCTCGCCTTGACCGGCCCGCTCGCGCAGTTCGGCGTAGGCCAGGGCCATGAACCAGGAGGTTCCGCAGCCGACGACGGCCACGCGCTCACCGAGCCGGGGCAGGACGTCCTGGTGGTCGGTGACCGAGGCGGCCGCCATGCGCCAGCAGTCCGGCTGGGAGGCGATCTCGCGTGAGGTGTGGGAGGTGTGCGCGGAGCCCGGGGGAGTGGACATCGGTGCTGGATTCCTTCGAGGTGTTGCGCGGTTGCTGAATCGACCGTGCGAGGGGTGTGGGGGAGCGGCGTCGGCGCTCAGTCGAACGTCTCGATGTACTCCTCGCAGGGCCCGAGGTCGGGCGCGTCCACGAGGTCGACATGGTGGCCGAAGCGGTCGAGTTCCAGGATCGTCAGGAGGTTGTCCCCCGTGCGCAGCAGCGGACGGGGAAGGTACAGGGTCGTCTGCGGGCCCACGTCCCAGTAGCGGCCGAGCAGGGTGTCGTTGACCCAGACGAAGCCCTTGCCGAAGCCGGGCAGGCTCAGGAAGGTGTCGGCGGGCTCATCGACGTGCAGGCGTGCGGTGGCGATGCCGCGGCTGTCGGCGGACTCGGCGGCCGTGCCGGCGCGCGTGAGTTCCTCGGCGGTCCACTCGTCGAGCGGCAGGGGGCACATGGACCATCCGTGGACGAGCCGCCGCTCCACGCGGACCCCGCCCAGAATGCCCTTCCCCTGTCCCAGCAGGGGGCCGTAGTTGATGCGTCCCTGGTTCTCCACCAGCAGGTCGAGTTGGATCGCCGCGCCCGTGCCGGTGACGCCGAAGGACGCTGTCGGCCGGTCCAGGACGGTGACGAGGGAGCCGTCGACGAAGACCTGTGCGCGGTCGTGGAGGCCGGTGACCGTCACCTCGTGGGTGCCGGGCGGTACGACCGGGTGCGCGGTGTAGAGCACGAGGCCGGAAGCTTGGCCGAGCTCCTCGAAACTCAGCGGGTTGGCGGCGTGCACGGGCGTCGACACCGACCTCAGTGCAGCCGGCAGCGCGGATCCGCGGTGTACGGGGAGGGTGGCGGGCTCCAACAGGGGCGGGTCGTCCGGCGGCTCGGGGACGGGCCGTGTGCTGTGGGGGGCGAGCTTGTCGCGCAGCGCGTAGAACTTGCTGGTGAGCGCGCCGTGTTCGGCCACTGGGGCGTCGGAGTCGTAGCTGGTGATGGTCGGCTGGAGGGCCGTGCCGTCGTGGTTCGCGCCGGCCCACAGCCCGAAGTTGGTGCCGCCGTGTGCCATGTACAGGCTCAGCGACCCGCCTTGGGCCAGGATGCCGTCGACGTCGTCGGCGGCGTTCGAAGGGGATCGGACGTGGTGCTTCTCGCCCCAGTGGTCGAACCAGCCGTTCCAGAACTCGGCGCAGAGGAAGGGCTCGTCGGCGCGGCGTGAACGCAGCAGCCCGGCAGCCTGGTCGGGGCGTGACCCGAACGTGGCGGCCGCGAGTTCGCCGGGAAGGGTGCCGCCGTCGAGCATCAGCGGTGTGGGCCCGTCCGCGGTGAACAGGAGCTCGCGGACGCCGCGTGTTGCCAGGGCGTCGCGCAGCCAGCGCATGTAGGTGTGGTCGTCGCCGTAGCTGCCGTACTCGTTCTCGATCTGCACGGCCACGACCGGGCCGTCGTGTGCCGCCTGGTGGTCGGCGACGAGCGGGATCAATGCGTCGAACCAGCGTCCGACCTCGTCGAGGAACTCGCGGTGGCTGCTCCTGGGCCGCATGCCGGGCCGTCCGGTCAGCCAGGCGGGCAGGCCGCCGTTGTCCCATTCGGCGCAGATGTACGGGCCGGGGCGGACGATGACGTCGAGGCCGGTTTCCTCGGCGAGCCGGAGGAACCGCGGCAGGTCACGCCAGCCGTCGAAGCGGATGTCACCGCGTCTGCGCTCGTGGAAGTTCCACGGCACGTAGGTGTCCACGGTGTTGAGGCCGAGTGCGGCGACGCGCCGGAGGCGGTCGGCCCATTGCTGCGGGTGGACGCGGAAGTAGTGCAGGGAGCCGGACAGGACCCGGTGGGGCTGCCCGTGGCGCAGGAAGGCGCCGTCGGCCCAGCTCAGCACGGGCTGCGTGACGAGCGCGTCGGTGACGGGGGCGGGGCGGGCGGTGCCGGCGGACTCGGTGGTGAGGGCGGGAGGGGTCATTTGACGGCTCCGGCGGTCATGCCCGCGCGCCAGAAGCGCTGGAGCGCGAGGAAGGCGATCAGAAGCGGGGTGATGGAGACCAGGGACCCGATGACGACGAGGGGCGGTGGTACGGCGACGTGGCTGGCGTTCCAGGCGACGAGACCGACCGTGACCGGCTGCAGCCGGTCGTCTCCCAGGACCATGGCGGGCAGCAGGTAGTTGTTCCAGATCTCGACGAACTGGAACAGGAAGATCGTGACGAGGGCAGGGAGCATCATCCGCACCCCGATCGTGCGGAAGATGCGGAATTCACCCGCGCCGTCGAGACGGCCGGCTTCGAGGACCTCGTCGGGCACGCTCTGCTCGGCGAAGACGCGCGCCAGGTAGACGCCGAAAGGGCTGATGACGCTCGGCAGCAGGACCGCCAGAGGGTTGTCGATCAGGTGAACGCCCGAGAACATCAGGTACAGCGGCAGAGTGAACAGCACCTTGGGCACGAGGACGGCTGCCAGGACCAGGGAGAACAGAGTTCCGCGGCCGGGGAAGTCGTACTTGGCCAGGGCGTACCCGGTCAGGGCGGAGAAGACGGTGCCGATGAGCGCGCCGACGCCGCAGTACAGAACGCTGTTGAGCATCCAGCGCCAGAAGATGCCGTCGTCCTGGCTGCTGAGCCGGGCGACGTTGTCGAACAGGCCGAAGCCGTCGAACCACAGGCCGCTGCCACTGAACTGCTCCCCGAAGGGTTTGGTCGCAGACACCAGCAGCCACCACAGCGGGAAGAGGAAGTAGAACGCGGACAGTCCCAGCAGGGCGAGTACGGTGACGCGGCCGGCCGGGCGCGTCTCGCGGCGGGGTCCGATCCGCTTGGGCGCCGGCGAGGGGGCGGGAACGGGGGCAGGGATCACCGTGGTCATGCCTGGTCTCCTCGGCGGGTCAGCTTGAAGAAGATGAGTGACACCAGGCCCACGGCGACCGCGAGCAGGACCGACTGGGCTGCCGCGTACGGGTAGTTGCCCGCTGCGACCGCGCTCTGTGCCGACATCAGAGGCGTGAAGGCGGAGGAGATCGAACCGCCGGAGACCGGCTGCAGCACGGTCGGCTCGTTGAACAGCTGGGCCGATCCGATGATCGAGAACACCGTGGTGAGCACCAGCGCGCCCCGTACCGCGGGGATCTTGATGCTCCAGGCGATCCGCAGGGCGGAGGCTCCGTCCATCCGGGCGGCTTCCAGGACCTCGGCGGGGATGGACTGCAGGGCCGCATAGATGATGATCATGTTGTAGCCGGCCCAGCTCCAGGTGACGATGTTGGCCACCGACCACAGCACGATGTCGTCGTCGAAGAACGGGATGGTGACGGAGAACGGTTCGAGCAGCCGGTTGAGCGGGCTGGACGTCGAGGAGTACATGAACGACCACACGAGTGCGGCACTGACGCCGGGGATCGCGTAGGGGATGAAGCTCGTCAGTCGGAAGAAGCCCCGGCCCCGCGCCGACTTGGAGTCGATGAGCAGGGCCAGCACCAGTGCCACTGCCAGCATGAGCGGCACCTGTACGACGCCGAACAGGGCCACGCGGCCGAGCGAGGCCGTGAACGATCCGTCGTGCACGGCGCGCACGTAGTTGTCCAGAGGGGCGAAGACCTCCGTCGGGGCGGTCAGGCCCAGACCCGACCGGCGGACGGTGAAAAGACTGTTGTAGGCCGCGTACAGGATCGGTGCGATGTACATGGCCACGAACAGGGCGACGAACGGGGCGCAGAAGAGCAACGGGCTCAGAGGCCGCGGGCGCCCGGAGAGGGCTCCGCGTGCGGGCCGGGACGGAGCGGCGGCCGCCGGGCGCCGTCCGGTTGCGCGTACCGAAGGGGAGGCTTGGGTCACGAACGGGGTCCTCACTGTGGTTCGCCCCGCCGGCCGGCGAGTCAACGGCGGGGCGACTGCTTGCACTTGCTGATGGCGCGGCGGGGGCGAGAAGGATCCCTGTCGCGTCCCCGCCCCGGCGACAGTGCTACTGCGCGACCGCCAGGCCCTGCTTGCGCATTTCGGCCAGGGTCGAGTCCTGAGCGTGGCCCAGGGCCTGCGCGATGGTTCCCTTTCCGGTCCACGCCTTGCCGAGGCCGTCATTGAGGTCCGCGACCGTGGAGGTCATCAGCGGGCCCCAGGTCCACCCGGGGTCGACGTCGGGCGCGGCCGCGGCGAAGACGTCGTAGATCTGCTGGCCGCCGAAGTAGGGGTCGGCCTTCAGCTGCGGCAGGTGGAGCAGATCGTTCGCTGCGGGATAGAGCGAAGCCTTCTCGACCAGCGTGCCGAACGCCTGCTTGTCGGTTCCCAGCCAGTGGGCGAACTCCCATGCAGCCGCGGTGTTCTCGCAGCCCTTGAGCACGGCCGTGGCCGATCCGCCCGCGTTGCCGACCTTCTTGTCGCCCTCCTGCCACTGCGGCATGGGGGCGACGGCCCACTGCCCGTCCCCGTCCTTGGCGCCGCCCTTGATGACTCCCGCCTGCCACACCGCCCCCACGACCGTGGCGATGTCGCCGTTGCCCAGCCCCGTGTACCACGCCTGGTCGTACATGGGGGCGCTGCTGATCAGGCCGTCGTTCGCGAGGCCCTGCCAGTAGTCCGCGACCTTCTTGTTCTCCGCGGAGGCCATGTTGACCTTCCAGGCGTCCTTGTCGACGCCGAACCAGTCGGCGCCGGCCTGCCAGGCGAGCCCGGCGTAGTCGTAGTCGAGGTAGGGCGAGGAGATGAACCGCTTGGGGTCGGAGGCGTGGATCTTCTCCCCCGCGGCGCGATACTCGGCCCAGGTGGTCGGGGGCTTCAGACCGAGCGAGTCGAACAGCTTCTTGTTGTAGAAGAGGGCCATGGGGCCGGTGTCCACCGGAGCTCCGTAGACGGCCTTGCCGAGACTCACCGCGTTCCAGGCGGCGCTCTGGTACTCCTGCTTGGCGGAGCCGGCGTGCTTCGACACGTTCTGGAGGGCGCCCTGGGCGGCGAAGCTGGGCATCGTCTCGTACCCCACCTGGGCCAGGCAGGGTGCGTTGCCCGCCTTCACGGCGTTCAGCATCTTCTGGTAGCCACCCTTCGCCCCGGGCTGCACCGTTTGGTAGGTGACCTTGATGTCCGGGTGGCCTGCGTTGAAGGCGTTGACGGCGTCCTCGTAGCCGGGAGCCCATCCCCAGAATGTTATCGATGCCTTTCCGGGGGTCGATGGGGTGCCGGACGCCGACCCCGAGCAGCCGGTGGCCGCAAAGGCGAGGGTGAGGACTCCCGCCGCTCCCACAAAACGGATGAAACTACGCTTCACAGCTCCTCCTGAGTGCCGTGGCAGGCAACGGAGACGTCCTGCACGGGGGCCGCCTGTCCGACGGGGCACACCGACGGTGTCGTCCGCCCGGTGTGCTGGCCGAAACTATGGCAGAGAATGTTATCGATGCCAATAGGTGGTAGCGGTTGGTGTCCTGGCCAGTGAAACTGCACGTGAACAGCCATGCGAGCGATATCATTGACCAGGTCGGACAGAAGAAAGGGATCCCATGGCGAAGAGCGGTGACACCCACAGCGGAGCGCGCCCCCCGGGCATGGTGGACGTTGCCCGGGTTGCGGGCGTGTCCGCGCAGACCGTCTCGCGCGCGCTCGCCGGCCACCCCAACGTGCAGGAGAAGACGCGCGCGAAGGTCTTGGCGGCGGTCGACCAGCTCGGCTACCGCCGCAACAACGCCGCGCGGATGCTCTCGTCGGGCCGGAGCCGGAGCATCGGCGTCGTGACCCTCCAGACGAGCTTCTACTCCAGGGCAGCCGTAACCTCCGGCATCGAGAAGGCTGCCCATGAGGCCGGCTACGCCGTCAGCGCCGCCACCACCGCCTCGCTGGACACCTCCGCCATCGAGAACGCGCTCTCCCGGCTCGCTGACCAGGACGTCGAAGGGATCATCCTCTCGGTGCCGCTCATTCATACCAGCAGCAGGATCGAGCAGCTCACCCGCTCCACGCCCACCGTCACCATCGACGGCTCGCGCACCGACGCGACCGAGGTCCTCGCGATCGACCAGGTCCAGGCCGCTCGCATCGCCACCCAGCACCTGCTGGACCTCGGACACGAGACGGTGTGGCACATCACCGGCCCCGTGGAGTGGCTGGAATCAGCCCACCGCCGCGACGGCTGGCAATCCGCCCTCGAAAGCGCGGGCTGTGCGGTGCCGCCACCGCTGGAGGGGGACTGGTCACCCGCCTCGGGCTACCGGAACGGCCTGGTGCTCGCGCGGATCCCGGACGTCACCGCCGTTTTCGTCGCGAGCGACGAGATGGCCTTCGGGGTGATCAGGGCCCTGCACGAGGCGGGGCGGCGCGTACCGGACGACATCTCGGTTGTCGGATTCGACGACATCGAGCTCGCCGAGTACTGCTCACCCTCCCTCACCACCATCGCCCAGCCGTTCCAGCACATGGGCGCCCTCGCGGTGACCCATCTGCTCCGCCAGATCGACGCCCCCGGCCCCGTCCCCGAGCCGCGCTCGGTCGAACCGCGCCTCGTCGTACGTTCCAGCACGACGACCGCGCCCGGTCGCTGAGCCCTGATGCCTTGAGGGTGCGGACGCCGGGCTGCCGGGCGTTGAAGTCGTCGGACACGGGTGCAGGTGCAGGCGGAGGGAGCCGGCTCACGGCGTGATCTCGAGTGGTGGAGCGGTGCACAACGCGGCACTGTGCGCCGGGCACATGCGCCACGCCGGTGACTGTGCCCACAGCACGGTTCTGGTCGTGGTGTCCTGTTCATGGCGCCTCGGCCACCGCGTGCCACGAGGTCGCCCTCGGGCTGTCCGGCCGGGGCCCGGAGCCCTCCGACGCCCCGTGCACCGCCGCCGCGGCGGACTTCGAGGCCCACCGCATCGACTTGCCGGTGCCGGGTACGAGCAGCGCGGCCGTGGTGCGCGGTGGCGCGATCGTCCTGGACATCGCGCACACCGGGACCCTCGTGGTCACTGCGGCGCGGATCGTGCTCGGCGCGCCCGTGCCCGCGGACACGACGTCGCCTGCGGATCGGCCGGGCCTGTTCCGGTACGCAGGGCGGCCCGCGCTCTCGCTGTACGCGCGCCGCGTGCCGGCCCATCTCACGCCGCGGTCGGTGTACTTCCAGAACGCCGTCCGGATGCCGCTGGCCCTGGCGGCCAGCCGGATGATCGAGGGCGTGCTCGATCTGTCCCACGGCGTGTGGACGCTGTTGGCCACCCCACCGTGAGAGGGCGTTTCCTCCTGTTGTTTCATCCCGGATTGCCGGGTTGATAGTGGTTCATGCGCCGCGCCATGTGGGGGTGGATTCGACGGTGAGTCTGCGGGTCATGAGGTTGATCATCGCGAGGTGGATCATGGCTTCGGAGCGGTGGGGGCAGGCTTCGTAGTCGCGCGTGAGACGGCGGTGGTTCATAAGCCAGCCGAGGGTTCTTTCGACGGTCCAACGGCGGGGCAGGACGGTAAATCCCCTGGTGGTGGGGTCGCGGCGGACGATGTGCATGTCGATGCCGAGGGTGGCGGCGTACTCGACGAGGTGCTGGCGGTAGCCGCCGTCGACCCAGGTCTTGCGGATGGTGGGATGCTCGGATGCGACCCGTTCGATGAGGGTCTGCCCGGCGATTGAGTCCTGCACGCTCGCGGCGGTGACCACGACGGCCAGGAGGAGTCCGACGGTGTCGATGACGATGCTCCGCTTGCGTCCGACAATCTTCTTTCCGGCGTCGATGCCCTGCTCGCAGGCGGGCACGTTGGTAGAGGTTTTGATGCTCTGGGAGTCGATGACGCAGGCGGTCGGTTCCTCCTCGCGGCCCTCCTGCCTGCGGACTTGACGTCGCAGGAGGGTATTGAGCTGGTCGAAGACACCCTCTTCCTGCCAGCGGGCGAAGTAGGCGTAGATGGTGTTCCAGTGCGGGTAGTCGTGCGGAAGGTAGCGCCACGGGATGCCCGTCCGGTTCACGTAGAGGACTGCGTCCAGCAGGCTCCGCAGATCGTGGTCCGGAGGCCGGCCGATGTCCAGGCCTCGGCCGCGGCGCTCGGACCGCCAGGCGGTCAGGACCGGCTCGACCAGCTCCCACCGGGCATCGGACAGATCGCTTGGGTATCGGCGGCGTTCAGGCATGATTCCGGGCTACCCAGGTGGCCCAGGCGCGCGGACCGGCGCCCGAAGCACACGGCGTGAAACCCGGCGGCTTGGGATGAAACAGGAGGAGGCAGCCCAAGAAGCCCGTCTGGCAGCCACTTTCGCACCATGAACCACACCAACCCCAGCAGCCCCGACCGGCCGCAAGCCCATACCGGCTCAAAAAACCAAAATTATGAGCTAAACGCCCTCTGACTGCCTGTTTCGTATCACCTGTGCGGGCTAGGAGTTGTCGTCAAAGTGTCACGCCCACATCAGGAGCGACGCGAGGGTGACAGCTGCTTGGTAGGACTGGGCGGTCTTGTCGTACCTGGTCGCGATGCCGCGCCATTGCTTGAGGCGGTTGAAGCACCGTTCCACGACGTTGCGGTGCTTGTAGACCTGCTTGTTGAAAGCCAGCGGTCGGCCGCCCCGGCTGCCTCGCTGGGTTCGGTTGCGGACCTGGTCGGATCGTTCCGGGATCGTGTGCGTGATGCCGCGGCGTCGCAGCCAAGAACGGATGGCCTTCGAGCTGTAGCCCTTGTCGCCTATGACGTGGTCGGGCCTGATGCGCGGTCTGCCCGGCCCGATCCGGGGCACCCGTATCGCGTCCATCACGGCGGTGAACTGGGTACAGTCGTTGATGTTCCCGCTGGTCAGGACGAACGCGAGGGGTCGGCCCGTCCCGTCGCGGGCCAGGTGAATCTTGCTGGTCAGCCCGCTGCGGGACCGGCCGAGGGCCGGGCTGCGGAGCCCCGTTACCGTCTTCGTGGCCTCGTAATGAGGCTCCCGGCCTTCGGCCCCGGTATGACTTGAGCCCCCAGTCGATGATGATCGAAAAGGTGGTGTCGCCGGTGTCGGAGGCAT

Protein sequences of DBSCAN-SWA_4

>NZ_CP024985|8452510:8500516|8490651_8491614_-|WP_030241673.1|DBSCAN-SWA
MSTPPGSAHTSHTSREIASQPDCWRMAAASVTDHQDVLPRLGERVAVVGCGTSWFMALAYAELRERAGQGETDSFAASRFPAGRRYDRIVALTRSGTTTEVLDLLARLRGQAPVTAVTADAGTPVADVADGVIELAYADEKSVVQTRFATTTFVLLRAHLESGGPLPRGVRTIAQAAADAERAVAAPLPEVMCAAEQITFLGDGWAYGLALEAGLKMREAAGAWTEAYPAMEYRHGPISIARPGRGTWVFGPAPHGLADDVARTGVAYVAESGDAAGDLDPLSDLVRAQRLAVHLAGARGLDPDRPRALSRSVVLAGAHA
>NZ_CP024985|8452510:8500516|8457340_8457652_+|WP_158741071.1|DBSCAN-SWA
MGETVMVRCCTAEQMRHFTDSVTEMVDRGRALRQLYAHQEEPPHRTRCARMTSGRINPISPACTTGERLAAERTVMLRPQSTLLRTLGTDRAVHCRWQCGGCW
>NZ_CP024985|8452510:8500516|8478182_8480342_+|WP_158741022.1|DBSCAN-SWA
MPLVLPLLPDDPARVGTYTLMGRVGGGGMGTVYLARTGSGRLAAVKTVRTELKDRPGFRDRLLLEAEAVRLLGSSHTAAFLAVDAEASLPWLATGYLIGPSLSEAVAVAGPLPVAAVVMLGAAVADTLTTLHRAGLVHRDLKPANLLISAQGPKLIDFGLARALGGPPLTAAGEPAGTPSYMSPELVRGEEHGPPGDVFALAAVLVFASSGHGPYDGGPGRDALRLLRDGAPPELTGVPDTLREVIRSALSPDPRDRPTLDELAAHWGPYEAARFSESLPGEVLADMSRRVDELASLGGTPLREDSPPLRPSYPSRRVLLAGAAAVAAGGASALWLTGRSPGFGGGSGAPGPVPSPSGGLPGGSPRQQWSVPVSAVYGPPVATEELVLLPGETVRGLSPTSGGMLWEVPSTRLRVAASGRRLAALAFDEELTPAAGYLDPLSGRLMPDAAGPHELGALSLYSEVLNADADTLYIRAYYEADKDRAEPWLLAYDLAAHRLRWRTRVAWGYTDRTEALYFRAVVANGRLIGSDATRVFAVDVRDGRFLWVTRLRSDAEAAAPGASGGVYPPVVSEHHVFDVSQVITAVDLLTGAPTWTLKPERDQTLLTSPVCVQGTVHIASHAFTAFEESTGRKLWTYEPGPSFQRIAVPGPFRGELYAAVSGGGQAVVAVDLAQRRASWTLSAQAAGMPDGPSDLTHRDDRLYLQAYQRLTAVRIDTRR
>NZ_CP024985|8452510:8500516|8466533_8466941_-|WP_158741063.1|DBSCAN-SWA
MAGVGVAAAITMVAAGPAAHATPAGGAVPQVAPKAGETPALDCFHVEIGSNATFFAVRPLLDVVGVAGLELREQGSTTWTRMRETWGDVFRLDSNRPLRAPFSLRLTNELGVTTTYINIIPANWTPEQSYCGTGT
>NZ_CP024985|8452510:8500516|8498809_8499649_-|WP_100660736.1|transposase|DBSCAN-SWA
MPERRRYPSDLSDARWELVEPVLTAWRSERRGRGLDIGRPPDHDLRSLLDAVLYVNRTGIPWRYLPHDYPHWNTIYAYFARWQEEGVFDQLNTLLRRQVRRQEGREEEPTACVIDSQSIKTSTNVPACEQGIDAGKKIVGRKRSIVIDTVGLLLAVVVTAASVQDSIAGQTLIERVASEHPTIRKTWVDGGYRQHLVEYAATLGIDMHIVRRDPTTRGFTVLPRRWTVERTLGWLMNHRRLTRDYEACPHRSEAMIHLAMINLMTRRLTVESTPTWRGA
>NZ_CP024985|8452510:8500516|8459472_8462379_-|WP_100660740.1|DBSCAN-SWA
MAHLLSRNRTKPGPGTPPARLRRIGVLLAGAITAGLLSAAPASADPAPAAPITLVSVTATADDQLYALAADHTAVYRWNGKGTDWTKVGGPAQDLYVGGAGLFATSLGSGALNKYNGQPGDWSQIGGAGADFAVTGDHLYGLNPDRSAVYEWNGTGTDWTRIGGPAQDLEAGGAGLFATSPDGKLHKYNGQPDTWSEIGGAGADFAVTSDHLYGLNPDRTAVYEWNGKGTDWTKVGGPAQDLHAGGAGLFATSPDDKLHKYDRRADTWTEIGNAGKAFAVGSTRLYGLASDGNSVHRWSGQGADWTALGAPSAPGAPVPQAADPSPEPQSAPPGMGSEAQDGAEAESVPEAGSPSSVRGALSDIAGPELSVTAKGDLYALAPDHGSVWKHEGDNHWTKIGGPAESVHAGRLGVFARHPDTGAIYRYDGEIGRWSQIGDASADLEVTGDHLYRLSSDRSAVFEWSGQGTDWTKIGGPADQLYAGGAGLFATRPDTGHLYQYNGTPDHWTEIGTPGAAFAVSDEHLYGLSPDRSAVFEWSGQGTDWTKIGGPADQLYAGGAGLFATRPDTGHLYQYNGTPDHWTEIGTPGAAFAVSGEHLYGLSPDRSAVFERTSGDNWQYRGGPSEALQAVRDEDTLRELRGDDYVRQYRQASILADTKLMEWLAQNGAGILLELLGVKDIEKCLSAPGKEKIKPCLLAAANFSTVITAVRKADKVQDAIKTVAVGLPRFRSEVVAARNVVVQAREILDRNAKDLADDFTVNKPDRADCRRNGAGWLDLGTRDVAHGSRATAMNACLDTAYLTAHAQRGSPTTAAVRPPGYNWATATAGYLRIKDIPQRINNCHLLGKQLTGSGEDLDNLVTCSRAANAQVKGDEGFANDMKALEGEVKKAVDAGQVVRYQVTPVYSGPRTVPVKLEISAVGMYPDGRPGGVLIKRAVENKLFQPQTQKWHNLGLWVMNGKAVPTGNTP
>NZ_CP024985|8452510:8500516|8470959_8471433_-|WP_158741016.1|DBSCAN-SWA
MPWSTAKNGNPFNVPRMVLYRLGDAIDTLSQITRVVTQVYRENGRAEHDLNSYRQPLQERSRTDSLDDSDHHYLAGLLGRPLPADNGSATGLYDWGRSEAEHPDLPEVVNTRACLYALRASGSEEPETVFASLNEPTRAVARAVAQHLLPPCDDDLP
>NZ_CP024985|8452510:8500516|8488734_8489673_-|WP_030241670.1|DBSCAN-SWA
MILTVTLNAALDVTYFVDEVTPHASHRVTQPVERAGGKGINVTRVLAALRHPVLATGLVGGTTGRILREDLRASGLKDALVPVRGESRKTITVVSERNGDATVFNPPGPHVDPQSWRAFTRRFAELAARADVVVLAGSLPPGLPCDSYAGLLATARDAGAVTVLDTSGAALLAALDAGPDVIKPNAAEIREVTGRSDVADAAAELQARGARTVVASDGPQGLHAVTPEGRYRTLPPAQLRGNPTGAGDACVAALAAGLATGLPWPDLLRDAVALSAAAVSAPLAGDFRRDLYDQFRTTATVSVERPHAADSH
>NZ_CP024985|8452510:8500516|8455841_8456231_-|WP_030242126.1|DBSCAN-SWA
MSSKRSKNPALPVLDDAFRLASVKDAEESTRDLAARLATTELRRVSHPGRVTWEPTDQAEPVPVPPTVVDGEGDLWLRDRGTGTWTMPEFNPKEFPARCGEVLTWNQLAREFGPLTALADDRRIGGRRR
>NZ_CP024985|8452510:8500516|8495533_8496829_-|WP_037689285.1|DBSCAN-SWA
MKRSFIRFVGAAGVLTLAFAATGCSGSASGTPSTPGKASITFWGWAPGYEDAVNAFNAGHPDIKVTYQTVQPGAKGGYQKMLNAVKAGNAPCLAQVGYETMPSFAAQGALQNVSKHAGSAKQEYQSAAWNAVSLGKAVYGAPVDTGPMALFYNKKLFDSLGLKPPTTWAEYRAAGEKIHASDPKRFISSPYLDYDYAGLAWQAGADWFGVDKDAWKVNMASAENKKVADYWQGLANDGLISSAPMYDQAWYTGLGNGDIATVVGAVWQAGVIKGGAKDGDGQWAVAPMPQWQEGDKKVGNAGGSATAVLKGCENTAAAWEFAHWLGTDKQAFGTLVEKASLYPAANDLLHLPQLKADPYFGGQQIYDVFAAAAPDVDPGWTWGPLMTSTVADLNDGLGKAWTGKGTIAQALGHAQDSTLAEMRKQGLAVAQ
>NZ_CP024985|8452510:8500516|8485253_8487752_-|WP_030241660.1|DBSCAN-SWA
MITPRSRLAGALAAAALVISGGSTLMMPSASAASTAPVPAPATYSVTVGAKGSWTHPDDTPAGTYVDKDGTFYFQQAHALYGADDPRKWTFFTGTNLDTATRSVAISDAVNPANSNDRNNDTTWRCNNSPTGLEATPAPAGSSYAHRNYCDLAGVWVDPDTGDWYGLVHNEFTPQPFTDGLHYDGIDYAVSKDQGRTWTIKDHVITSHYSTERGDDAAFPQQTFHYGTGDQRLFVDTGSGYFYAFYGSRIVNKGGGWAAFYGHVARAPISAKLAPGSWQKWYDGAWSEPGLGGRESNMVPVGSGSATGYTPPSKEYDPANSGSVSQQVAAGLMPPTSPLFVMDITYNAHLGLYIGQPQAVDQSGNASQEIYATADLTTQKWFRLGDTGSYKNASWYRWFLDSGNKTSSTIVGKNFRSYCSFGCSNGASSEYVNLAIDTTEPAAPVDTSKAYRIGSAGGRVLAQVSGSSATTSSAAATGSGLESWTFASNGDGSYRIANSGTGQLLGVGAASTATRAWGTKPTVTAAGTGGPTVGQQWFVIRGTSPADGASTGTYKIVNRYSGLVIGLSADSTRLAETTPTRSWTNTTGNAVGGTRTAGEQTLTLIPIAQVPETVMVTNPGNQAGTVNKAVSLQAVATDSLGKPLTFTATGLPTGLSISSSGLITGTPTAAGASTVTVTAASGTAGGTATFTWAVTASLDGVHTLTAGGKALDNPGHSTTPGTQLITWSPNGGANQSWTFTQQTDGTYQLKNSESGLCADVEGGSTSPGAKIVQWTCSNGANQRWNITRQANGTHTVASAWSGLLLTTASSANGALVTQQPDTGTTLQQWTVN
>NZ_CP024985|8452510:8500516|8481736_8482276_-|WP_100660738.1|transposase|DBSCAN-SWA
MRYPQGGGLTAERQAFRERVRMEAVAMFAVGRGSGEVAKELRVSVRSVQRWRQAWSAAGQDAVRSRGPACRPKLSDALFAVLEEELAKGPVAHGWPDQRWTLARIKTLIGRRFHKSMTLSGISQMLRRHGWSHQVPARRAVERDEAAVDGWVKDVWPHVETPRRRSKSGSSSKTKPDSR
>NZ_CP024985|8452510:8500516|8498257_8498758_+|WP_100660737.1|DBSCAN-SWA
MPTARFWSWCPVHGASATACHEVALGLSGRGPEPSDAPCTAAAADFEAHRIDLPVPGTSSAAVVRGGAIVLDIAHTGTLVVTAARIVLGAPVPADTTSPADRPGLFRYAGRPALSLYARRVPAHLTPRSVYFQNAVRMPLALAASRMIEGVLDLSHGVWTLLATPP
>NZ_CP024985|8452510:8500516|8484652_8484913_+|WP_030241655.1|DBSCAN-SWA
MTGQPHAVRFSAPAAKVLDTLPEHAEDTVWDVLDAAAVNPWGFGQWNADDPEGEDVRYASVGRLSLTYWVNRPLHRLTVLNIVWLG
>NZ_CP024985|8452510:8500516|8455456_8455660_+|WP_030242128.1|DBSCAN-SWA
MATGTVKWFNAEKGFGFIAQDGGGPDVFAHYSAINSSGFRELQEGQAVTFDVTQGQKGPQAENITPA
>NZ_CP024985|8452510:8500516|8462529_8464356_+|WP_158741067.1|DBSCAN-SWA
MVKAGRPQGGPKGETDEANELAVFLRDLTQDFTVRELAERYKISKTSWGEYRSGTKTIHLHLLKRLVHDLVRDERARAARWALAQRLHEQATTAQQPLGPDEPNTAMEGVTAAQAAAQATAALQDAERLVHILLGVIAGLQMPSQHGTAPGADAAGLASAADQAATDLREAHHRLDQVRLVQDAVRRVRDEATAHDDPSGAADAASRADDAGRSGNDEHLPVPYTAASREASAILIVSRAALVEQYAAARLLSARAAGVHAIEPTAVQNTPRGALALTSPPRSPTAVSPPSDRSRRRRQIVMMAVAVTLAASLSAVAAVTLVRNGQHPPLEQANRPTPAPAASLPPPTLSPSPPASPTPSPSPDLIDPTSPPNPTRSTETSVTAVPDDYLGTWQGEFTKPGDKAPTLRRIEIRKGAVGAETADILTSTASSLCQSKGTLISAGTLLVLTTNPTSGIPSHLCTTNADITLRRQGDTDLTWKSEGTTATLHRTAPQNQTIPAPFIGTWRAQDGNDTTSSVRMTINQGTPGHARAEFVWDGDAHHCEGFSVLASIGDALTFSPETVTSSEPQRFCTQTPTRLVTQSQGNTLHVEWADDGGFFRSFTFHRVG
>NZ_CP024985|8452510:8500516|8454936_8455218_+|WP_100660743.1|DBSCAN-SWA
MGRAAEMLGTTQGFLRAIGEACLITPLRSAGGHRRYSRYQLRIAARARELVDQGTPVEAACRIVILEDQLEEAQHLNVGYRRAAESANPTAAA
>NZ_CP024985|8452510:8500516|8452510_8453386_+|WP_100661214.1|transposase|DBSCAN-SWA
MVDHVFVIRRHELTDVEWELLAPLIPSAGRGRPRAEDRRVINGMVYKIRTGVSWRDLPERYGPWKSVYTRFRRYAIDGVFTRALQQIQAQADAAGDIDWLVQIDSTIVRAHQHAAATGRKRGKHRTDEPDDHALGRSRGGLTAEIPLACDGRGRPLAVLLTPGQRHDGVCVRPLPGRIRVPRTGRPRCRPDHVIADKAYSSRGFRAYLRRRGIGHTIPEKNDQKMHRRNRGRRGGRPTAFDSRIYRRRNTVERCFSQLKGFRGIATRYEKTATSYEAAVTLASLLLWARSI
>NZ_CP024985|8452510:8500516|8491691_8493545_-|WP_078950761.1|DBSCAN-SWA
MTPPALTTESAGTARPAPVTDALVTQPVLSWADGAFLRHGQPHRVLSGSLHYFRVHPQQWADRLRRVAALGLNTVDTYVPWNFHERRRGDIRFDGWRDLPRFLRLAEETGLDVIVRPGPYICAEWDNGGLPAWLTGRPGMRPRSSHREFLDEVGRWFDALIPLVADHQAAHDGPVVAVQIENEYGSYGDDHTYMRWLRDALATRGVRELLFTADGPTPLMLDGGTLPGELAAATFGSRPDQAAGLLRSRRADEPFLCAEFWNGWFDHWGEKHHVRSPSNAADDVDGILAQGGSLSLYMAHGGTNFGLWAGANHDGTALQPTITSYDSDAPVAEHGALTSKFYALRDKLAPHSTRPVPEPPDDPPLLEPATLPVHRGSALPAALRSVSTPVHAANPLSFEELGQASGLVLYTAHPVVPPGTHEVTVTGLHDRAQVFVDGSLVTVLDRPTASFGVTGTGAAIQLDLLVENQGRINYGPLLGQGKGILGGVRVERRLVHGWSMCPLPLDEWTAEELTRAGTAAESADSRGIATARLHVDEPADTFLSLPGFGKGFVWVNDTLLGRYWDVGPQTTLYLPRPLLRTGDNLLTILELDRFGHHVDLVDAPDLGPCEEYIETFD
>NZ_CP024985|8452510:8500516|8497058_8498093_+|WP_030241684.1|DBSCAN-SWA
MAKSGDTHSGARPPGMVDVARVAGVSAQTVSRALAGHPNVQEKTRAKVLAAVDQLGYRRNNAARMLSSGRSRSIGVVTLQTSFYSRAAVTSGIEKAAHEAGYAVSAATTASLDTSAIENALSRLADQDVEGIILSVPLIHTSSRIEQLTRSTPTVTIDGSRTDATEVLAIDQVQAARIATQHLLDLGHETVWHITGPVEWLESAHRRDGWQSALESAGCAVPPPLEGDWSPASGYRNGLVLARIPDVTAVFVASDEMAFGVIRALHEAGRRVPDDISVVGFDDIELAEYCSPSLTTIAQPFQHMGALAVTHLLRQIDAPGPVPEPRSVEPRLVVRSSTTTAPGR
>NZ_CP024985|8452510:8500516|8465407_8465617_+|WP_100661219.1|DBSCAN-SWA
MPEDPDELVDAIAVAVRAGDDRRIGLLLDRFKEVAGLSHLIRLRERLCGAGGAARVSARGIWWSATRTW
>NZ_CP024985|8452510:8500516|8468216_8468771_+|WP_158741061.1|DBSCAN-SWA
MRAAILTVAGSIIVGCLGLWSGVFSGKDDRDDPKPAPSASQAGPSSGGAGPGQVLPACGGKPGLDVTVEPKQLTVASDGSLTAEVNCTLGAGLHLSWIVQIDGVGKPVPHTNYYHKDDLGRPGPYTFDVHLSQAVPGSARTIYVVLTDDFSYRQLSDNRNPDGSLLKLPNGARKVSNSVLVKRY
>NZ_CP024985|8452510:8500516|8469860_8470127_-|WP_078950757.1|DBSCAN-SWA
MSPCGVVKWFDPDRGTGLISQDGTGPDIRAEARAIHGKGPCLRPGDRVLFDLTHDSAGLRADNIHRPEDALSQDGPGQQTDRRGNSRL
>NZ_CP024985|8452510:8500516|8465682_8466027_-|WP_159038052.1|transposase|DBSCAN-SWA
MSECDDLDDGEWAVIRALLPRCGPGGPDYRAVVNGILWQQRGGRRWHDLPARYGPWHRCAERLRLWQTDGTWHNVLTSLAASRPLPRRTEQTRDTPKSSLAREEIDDWNSPWLP
>NZ_CP024985|8452510:8500516|8484350_8484656_+|WP_030241652.1|DBSCAN-SWA
MSAQPEHTPIPSYAPSPGAPAELLAQLRADRRAPQWVPAFEREWTAALEESRRTFSLAGLYEVVQDWQGRLAHAPAVDAFVASGYDDGETIDMAELRGRRR
>NZ_CP024985|8452510:8500516|8472209_8473169_-|WP_030241633.1|DBSCAN-SWA
MDISSFISEDFGSVVAGGAALLAVPGVIVAGAIQGKRALQGAQAQAEAALRAAHEQAAKALEAAQAQAQATLETGRLQAQATLEGVREMSREAHAQWQRDRCEDIWAAFVAELDLLKAKEQATSHESEVADLLKAYAMVELMSPPVVLEQASRARNKAIEVDLMLFTLRMQARDMEQLELAKQRLRSDVTQGSGIADTRGLLAELVPGPDGDDMVDSPGSPEEYEDMRERFERCRAASDALEALAAVERAQGVQDAGERARQTLLAAGFRETQASSLVFTAQLDRDEQQQILAADKRELTRLRNVFVKEARKELDALGA
>NZ_CP024985|8452510:8500516|8457764_8458649_-|WP_158741069.1|DBSCAN-SWA
MLFSLSKPGVPWRTGLRSAAVVSLLAMGATACGAGGSSDNPQAGQAPQSTQATSTPDGKKTLDAPVAKGLGSLTSGNLTLLAFYDPSTGKETFSTTLPQYSEKNPWKRYSFSPDWKRHAWVKDGDLFVGSFTGSTITSAYDETPGVKIGGKPTFNGGKRAYRQPRFSADGKRIFALANDEKVYSADPSSPDQLTEEATLDQGSFFGGRSELLWDLTADGKVVKRPAPVHPERGGQATSPDGTKTLIYNGSGWFLKANGATGEPQLAFETLTDDTDKPVGSGPNPGMDVDIIGWY
>NZ_CP024985|8452510:8500516|8481164_8481812_-|WP_158741024.1|transposase|DBSCAN-SWA
MAARGNTAAALEVWIVFEDEAGFSMTPPTSRTWSRRGTTPVIRVRGRSQRRFSSAALCCHKPGERSRLIYRLKRHTDHKSGGRKCFAWTEYRDLLIAAHQQLGGPIILIWDNLNVHKERRMKAFIDAQDWLTAYHLPSYAPDLNPVEGIWSILRRTSQANTAFTDPSHLMRRLRHGLRQIQYRSDIINGCLTATGLILRSGSDGPYCEPPQHALL
>NZ_CP024985|8452510:8500516|8476456_8478148_+|WP_159038050.1|DBSCAN-SWA
MAPETVGGRVSSQAADIYALGVLLAHATTGRFPFGEGPPEVLAYRASHGKAELHGLPADLAEAVAAALAPVPGDRPTAAELSQTSALTRTTPVADGPAPGKVIIALAAQAQETADLGEGADRDLPRRTDVATRPLHRAADGPTRSSATGQTSPAGPLTRRALLSRLATGVAGAVLGAGTSLAWTATREPADRSLPDRPLATAPLPGLPPTALWRFDDVTARTTLLRVAGAGRYLVTRGETLHAHEVRSGKEVWERPIAFGRANPVLLVGGGRILVQTRDALVLCSLGDGRTHWIDRTFHTQNTTVLELLAVEGDTVWLHMGPAAGASATTHALAAFDLAARRELWRSELPADFVYELSLTPTPAGLLVEVLPEVDPHRDPYGTRKVPLACFDRTTGRSLWQRTYEGVYSGPASAVDETGRFYVLSTGRARAYDATPGSQLWESTLRFGGQHSPLLLTGTLLCETDPVNGVVALDRDTGRTVWQQRLDEPLQWFLLGTMATSASGRTLFVPTRRQLAALDLRSGERLWQMAFVGREDPSPLQLLATPDVLIVAQPSVVFALPAV
>NZ_CP024985|8452510:8500516|8480562_8481111_+|WP_030241640.1|DBSCAN-SWA
MAELGPVVWPPAPLRTERLVLREPEARDRAAFVDLFASSEVRTYLGGPRPRAELENAVPEVPGRRPGVFVVDHDGAMIGIVTLDRRGAERPGHVRPDAGEAELSYMLLPEAWGRGYALEACSAALGWFADVFPGEPVVLCTQVANDRSVRVAEKLGFTEMERFEEFDAEQWFGVWSSVPWSG
>NZ_CP024985|8452510:8500516|8473553_8475812_+|WP_159038051.1|DBSCAN-SWA
MDRITGGVGVDAGAFVGLGWNISVISTPAPRDAMGTSGIAFGAAGTGPCLRPLPAVPRCACLVPTPVGHLVCGTMTPVIASLPSGVPAELGGYRILGILGAGGMGTVYLAKGHGRRAALKTIRPELLNDQALRDRFAREVAAAASVRGRYVAAVLRSAPLAAVPWLASEFVAASTLEQAVRRHGPLSVPAVCALAGALGRALTALESAGVVHRDLKPSNVLMALNRPRVVDFGIARMAGDHTLTSAGQRPGTAGYMSPEQVMQEQLGPASDVFCAGALLVFAATGRHAFYNGDQAGADFRIVHEEPDLKDVPGTLARVVRGCMEKRPADRPTASEIAAELDPRGVGAGAAKRWLPPSVVADAAEIERAATALAGRAGLITRRNVLSAGAATVVLGGASVGALVWGRSSSESPSGHDPAPRWSGEPGEVPPVLWSLEGAAVTPRYPPGDIGGAAYFEERGGGLAAYDIVSGRRRWRGPAVREVLGGSRPVALDTDGAVLFLAAASGAVLKRIKADADRLLAVDRETVYVLDHSGEIRALRSADGTQRWHGKLPVPGPVAAAGGHGLVTVVSATGAVVALSAADGARMWRYDISGADRPAPDTEACRPAMSSEAVVLGGGAALTALAPRGGGRLWQLAADERAGFGEPTATGDKLYVRDGAQLRAVDAVTGKAAWTVAAGAELAPRPGPLVAGASVHAALANPELGVLAVHTGRAAAQYVFAPAIASAAPWQGAAVAGRVVWQRGSSVSAIPAM
>NZ_CP024985|8452510:8500516|8489669_8490659_-|WP_051841548.1|DBSCAN-SWA
MPEHAGSRTCVIALDVGGTSMKGALLDRTMRPLATLRSSTPRRQGHEATVDAITWLLRDLAGAAVGIGVEPVAAGIVVPGIVDEPTQRAVHSVNLGWYDLPLAAVLTDATGLPVRIGHDVRAGGTAESRLGAARGFDDALFVAIGTGISAALLVEGRPLRACGYAGEIGHLTVAPGAEQCACGMRGCLEAVASARAIAAVYAARSGHEVEGAEEVAALVARADPVACRVWERAVEALAEAFAACAAVLAPEVIVVGGGLSQAGGLLIDPLRIALDRRLSCHRRPKLVRAALGEQAGCLGAGLLGWEAADADPAAGRPVELVADPAGGAL
>NZ_CP024985|8452510:8500516|8499913_8500516_-|WP_159038049.1|transposase|DBSCAN-SWA
MPPTPATPPFRSSSTGGSSHTGAEGREPHYEATKTVTGLRSPALGRSRSGLTSKIHLARDGTGRPLAFVLTSGNINDCTQFTAVMDAIRVPRIGPGRPRIRPDHVIGDKGYSSKAIRSWLRRRGITHTIPERSDQVRNRTQRGSRGGRPLAFNKQVYKHRNVVERCFNRLKQWRGIATRYDKTAQSYQAAVTLASLLMWA
>NZ_CP024985|8452510:8500516|8493541_8494441_-|WP_051841549.1|DBSCAN-SWA
MTTVIPAPVPAPSPAPKRIGPRRETRPAGRVTVLALLGLSAFYFLFPLWWLLVSATKPFGEQFSGSGLWFDGFGLFDNVARLSSQDDGIFWRWMLNSVLYCGVGALIGTVFSALTGYALAKYDFPGRGTLFSLVLAAVLVPKVLFTLPLYLMFSGVHLIDNPLAVLLPSVISPFGVYLARVFAEQSVPDEVLEAGRLDGAGEFRIFRTIGVRMMLPALVTIFLFQFVEIWNNYLLPAMVLGDDRLQPVTVGLVAWNASHVAVPPPLVVIGSLVSITPLLIAFLALQRFWRAGMTAGAVK
>NZ_CP024985|8452510:8500516|8487917_8488754_-|WP_030241667.1|DBSCAN-SWA
MPLTATDDIIGPAYALNRGVGAFNVVQLEHAEAIVDGAHRANLPVILQISENTIRYHGSLAPIGRAALALAEQATVPVAVHLDHAESEDLVHEAVRLGFTSVMFDASKLPYGQNVAATRAVTEYGHRADVLVEAELGEVGGKNGAHAPGVRTDPAEAREFAAATAVDCLAVAVGSSHAMATRDAVLDFDLIARLRSATRVPLVLHGSSGVSDADLAKAVSAGMTKVNISTHLNGIFSATVRRELHRQPAVSDSRKYLGPAREEVAAEVARLLNVLAGV
>NZ_CP024985|8452510:8500516|8494437_8495256_-|WP_100661228.1|DBSCAN-SWA
MYIAPILYAAYNSLFTVRRSGLGLTAPTEVFAPLDNYVRAVHDGSFTASLGRVALFGVVQVPLMLAVALVLALLIDSKSARGRGFFRLTSFIPYAIPGVSAALVWSFMYSSTSSPLNRLLEPFSVTIPFFDDDIVLWSVANIVTWSWAGYNMIIIYAALQSIPAEVLEAARMDGASALRIAWSIKIPAVRGALVLTTVFSIIGSAQLFNEPTVLQPVSGGSISSAFTPLMSAQSAVAAGNYPYAAAQSVLLAVAVGLVSLIFFKLTRRGDQA
>NZ_CP024985|8452510:8500516|8453570_8453960_-|WP_030242579.1|DBSCAN-SWA
MDTTSVNLATARSAASVAGARGGTRDFLDRLVRPPAAETADTVVLVVSELVTNALRHAGGTFALALTAHPDSIEVAVHDTSPQTPRMRTPDLNGGTGGLGRPMVNRLARATTVTRWPSGGKTIRAVLPR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100661214.1|8452510_8453386_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	5.6e-21	43.7
WP_030242579.1|8453570_8453960_-	ATP-binding protein	NA	NA	NA	NA
WP_100660743.1|8454936_8455218_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_030242128.1|8455456_8455660_+	cold-shock protein	Q9AZD3	Lactococcus_phage	5.6e-17	65.7
WP_030242126.1|8455841_8456231_-	hypothetical protein	NA	NA	NA	NA
WP_158741071.1|8457340_8457652_+	hypothetical protein	NA	NA	NA	NA
WP_158741069.1|8457764_8458649_-	PQQ-like beta-propeller repeat protein	NA	NA	NA	NA
WP_100660740.1|8459472_8462379_-	hypothetical protein	NA	NA	NA	NA
WP_158741067.1|8462529_8464356_+	hypothetical protein	NA	NA	NA	NA
WP_100661219.1|8465407_8465617_+	hypothetical protein	NA	NA	NA	NA
WP_159038052.1|8465682_8466027_-|transposase	transposase	NA	NA	NA	NA
WP_158741063.1|8466533_8466941_-	hypothetical protein	NA	NA	NA	NA
WP_158741061.1|8468216_8468771_+	hypothetical protein	NA	NA	NA	NA
WP_078950757.1|8469860_8470127_-	cold-shock protein	NA	NA	NA	NA
WP_158741016.1|8470959_8471433_-	hypothetical protein	NA	NA	NA	NA
WP_030241633.1|8472209_8473169_-	hypothetical protein	NA	NA	NA	NA
WP_159038051.1|8473553_8475812_+	PQQ-binding-like beta-propeller repeat protein	T2AWK4	Cannes_8_virus	4.3e-09	26.4
WP_159038050.1|8476456_8478148_+	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_158741022.1|8478182_8480342_+	protein kinase	T2AWK4	Cannes_8_virus	3.9e-07	25.0
WP_030241640.1|8480562_8481111_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_158741024.1|8481164_8481812_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_100660738.1|8481736_8482276_-|transposase	transposase	NA	NA	NA	NA
WP_030241652.1|8484350_8484656_+	hypothetical protein	NA	NA	NA	NA
WP_030241655.1|8484652_8484913_+	hypothetical protein	NA	NA	NA	NA
WP_030241660.1|8485253_8487752_-	hypothetical protein	NA	NA	NA	NA
WP_030241667.1|8487917_8488754_-	class II fructose-bisphosphate aldolase family protein	NA	NA	NA	NA
WP_030241670.1|8488734_8489673_-	hexose kinase	NA	NA	NA	NA
WP_051841548.1|8489669_8490659_-	ROK family protein	NA	NA	NA	NA
WP_030241673.1|8490651_8491614_-	sugar isomerase	NA	NA	NA	NA
WP_078950761.1|8491691_8493545_-	beta-galactosidase	NA	NA	NA	NA
WP_051841549.1|8493541_8494441_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_100661228.1|8494437_8495256_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_037689285.1|8495533_8496829_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_030241684.1|8497058_8498093_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_100660737.1|8498257_8498758_+	hypothetical protein	NA	NA	NA	NA
WP_100660736.1|8498809_8499649_-|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.1e-10	38.0
WP_159038049.1|8499913_8500516_-|transposase	IS5 family transposase	NA	NA	NA	NA