CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP025009	Klebsiella pneumoniae strain AUSMDU00008119 plasmid pAUSMDU8119-1, complete sequence	0 crisprs	csa3,RT	0	1
NZ_CP025008	Klebsiella pneumoniae strain AUSMDU00008119 chromosome, complete genome	2 crisprs	csa3,cas3,DEDDh,RT,DinG,WYL	1	11
NZ_CP025010	Klebsiella pneumoniae strain AUSMDU00008119 plasmid pAUSMDU8119-2, complete sequence	0 crisprs	NA	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1777 : 103174

Escherichia_phage(25.0%)

protease,lysis,transposase,integrase

attL 1038:1051|attR 103833:103847

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1038:1051	attL	NA	NA	NA	NA
WP_001515717.1\|1777_2518_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	5.4e-25	58.6
1038:1051	attL	NA	NA	NA	NA
WP_004152065.1\|3661_4609_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	1.8e-12	30.6
WP_071527918.1\|4635_4947_-	EAL domain-containing protein	NA	NA	NA	NA
WP_004152067.1\|5011_5935_+\|transposase	IS5 family transposase	Q9MCT5	Escherichia_phage	2.1e-175	98.4
WP_004197688.1\|6607_6865_-	hypothetical protein	NA	NA	NA	NA
WP_020444838.1\|7466_8921_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004152070.1\|9903_11181_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_004178088.1\|11243_13241_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	9.7e-21	25.9
WP_085955172.1\|14280_15488_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	1.7e-100	63.2
WP_004178091.1\|16916_17348_-	silver-binding protein SilE	NA	NA	NA	NA
WP_003032875.1\|17598_19074_-	copper/silver sensor histidine kinase SilS	W8CYF6	Bacillus_phage	1.0e-27	30.1
WP_001572351.1\|19066_19747_-	copper/silver response regulator transcription factor SilR	W8CYM9	Bacillus_phage	2.1e-31	35.6
WP_000475512.1\|19936_21322_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA	NA	NA
WP_001246153.1\|21350_21704_+	cation efflux system protein CusF	NA	NA	NA	NA
WP_004152079.1\|21817_23110_+	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA	NA	NA
WP_004098958.1\|23120_26267_+	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	S5VTK5	Leptospira_phage	4.0e-61	22.5
WP_000758228.1\|26353_26794_+	hypothetical protein	NA	NA	NA	NA
WP_004098955.1\|26920_29368_+	Ag(+)-translocating P-type ATPase SilP	A0A218MNH6	uncultured_virus	7.6e-84	35.8
WP_000843497.1\|29408_29606_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_004118669.1\|29639_30377_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4JAF5	uncultured_Caudovirales_phage	1.2e-11	32.5
WP_001023257.1\|30665_31115_-	copper resistance protein	NA	NA	NA	NA
WP_004152083.1\|31348_33166_+	multicopper oxidase PcoA	NA	NA	NA	NA
WP_001242438.1\|33165_34062_+	copper resistance outer membrane transporter PcoB	NA	NA	NA	NA
WP_000025662.1\|34101_34482_+	copper resistance system metallochaperone PcoC	NA	NA	NA	NA
WP_004118344.1\|34486_35416_+	copper resistance inner membrane protein PcoD	NA	NA	NA	NA
WP_001188930.1\|35470_36151_+	copper response regulator transcription factor PcoR	W8CYM9	Bacillus_phage	8.7e-30	34.4
WP_004152084.1\|36147_37548_+	copper resistance membrane spanning protein PcoS	W8CYF6	Bacillus_phage	4.1e-18	26.3
WP_004152085.1\|37764_38199_+	copper resistance system metallochaperone PcoE	NA	NA	NA	NA
WP_004152086.1\|38430_38610_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_031944101.1\|40352_40862_+	major intrinsic protein MIP	NA	NA	NA	NA
WP_004152091.1\|40911_41409_-	N-acetyltransferase	NA	NA	NA	NA
WP_004152092.1\|41740_42067_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085903505.1\|42066_42777_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	2.9e-92	77.0
WP_004182005.1\|42785_43331_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004152095.1\|43406_43769_+	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
43465:43478	attR	NA	NA	NA	NA
WP_004152096.1\|45665_46202_+	N-acetyltransferase	NA	NA	NA	NA
43465:43478	attR	NA	NA	NA	NA
WP_004152097.1\|46234_46660_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.3e-52	72.9
WP_004152098.1\|46672_47962_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4J144	uncultured_Caudovirales_phage	1.9e-171	74.0
WP_004152099.1\|48009_49761_-	arsenite efflux transporter ATPase subunit ArsA	NA	NA	NA	NA
WP_004152100.1\|49778_50141_-	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_004152101.1\|50190_50541_-	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	1.4e-23	50.9
WP_004152102.1\|50898_51168_+	hypothetical protein	NA	NA	NA	NA
WP_004152103.1\|51155_51731_+	hypothetical protein	NA	NA	NA	NA
WP_004152104.1\|51761_52256_+	DNA-binding protein	NA	NA	NA	NA
WP_004152105.1\|52299_52668_+	hypothetical protein	NA	NA	NA	NA
WP_004152106.1\|52701_52905_+	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_004152107.1\|52953_53211_+	hypothetical protein	NA	NA	NA	NA
WP_004152108.1\|53286_53541_+	hypothetical protein	NA	NA	NA	NA
WP_003026799.1\|53716_53983_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_003026803.1\|53970_54453_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020314316.1\|54664_56011_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_004152113.1\|57853_58816_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_009483782.1\|58802_59552_-	diguanylate cyclase	NA	NA	NA	NA
WP_004152115.1\|59789_59987_-	hypothetical protein	NA	NA	NA	NA
WP_004152116.1\|59986_62782_-	heat shock survival AAA family ATPase ClpK	K4FB40	Cronobacter_phage	5.2e-129	41.0
WP_004152117.1\|62896_63466_-	small heat shock protein sHSP20	NA	NA	NA	NA
WP_004152118.1\|63500_63782_-	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	5.2e-05	38.2
WP_004118208.1\|64025_64289_-	hypothetical protein	NA	NA	NA	NA
WP_004118209.1\|64303_64567_+\|transposase	transposase	NA	NA	NA	NA
WP_000019473.1\|65768_66749_+\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_004152692.1\|67957_68827_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004152693.1\|68820_69831_-	phosphonate dehydrogenase PtxD	A0A1V0SBV6	Catovirus	1.4e-15	25.1
WP_004152694.1\|69839_70667_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_004152695.1\|70675_71539_-	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004153729.1\|71535_72363_-	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-20	37.6
WP_004217321.1\|73218_73923_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_044117068.1\|75226_75895_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.9e-130	99.5
WP_000018329.1\|76084_76900_-	aminoglycoside O-phosphotransferase APH(3')-Ia	A0A193DTG4	Autographa_californica_nuclear_polyhedrosis_virus	6.1e-163	100.0
WP_001067855.1\|77050_77755_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004199321.1\|78095_78917_+	cytotoxic family protein	NA	NA	NA	NA
WP_004152553.1\|78926_79184_+	cloacin	NA	NA	NA	NA
WP_004152552.1\|79268_79418_+\|lysis	lysis protein	NA	NA	NA	NA
WP_004178196.1\|80898_82863_+	TraM recognition domain-containing protein	NA	NA	NA	NA
WP_004152551.1\|82862_83594_+	hypothetical protein	NA	NA	NA	NA
WP_004153058.1\|83600_84131_+	hypothetical protein	NA	NA	NA	NA
WP_000165971.1\|84158_84338_-	Rop family plasmid primer RNA-binding protein	NA	NA	NA	NA
WP_000312627.1\|84406_84784_+	hypothetical protein	NA	NA	NA	NA
WP_001146176.1\|84845_85145_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000072676.1\|85134_85398_-	hypothetical protein	NA	NA	NA	NA
WP_001143775.1\|86028_89034_-\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	99.3
WP_001217881.1\|89195_89753_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
WP_063840280.1\|89986_90541_+	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
WP_001067855.1\|90891_91596_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004152398.1\|92212_93397_+\|transposase	ISAs1-like element ISKpn31 family transposase	NA	NA	NA	NA
WP_004152397.1\|93673_94993_+\|transposase	IS1182-like element ISKpn6 family transposase	Q9MBP7	Staphylococcus_prophage	1.9e-12	24.2
WP_004199234.1\|95242_96124_-	carbapenem-hydrolyzing class A beta-lactamase KPC-2	A0A1B0VBP7	Salmonella_phage	2.2e-73	52.2
WP_004152394.1\|96411_97191_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
WP_004199214.1\|97187_98213_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
WP_004152392.1\|98319_101349_-\|transposase	IS3-like element Tn4401 family transposase	NA	NA	NA	NA
WP_004152391.1\|101458_103174_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
103833:103847	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP025008

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP025008_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025008_1

4115240-4115335

Orphan

Consensus_repeat	Method
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025008_1

>merge|NZ_CP025008|1|4115240-4115335|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAACCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGTTGGCACTTTGTTGGCATTCTGTTGGCACAA

>NZ_CP025008|1|1|4115240-4115335|CRISPRCasFinder
TGGCACTTTGTTGGCATTCTGTTGGCACAA	CCTCGCCGGTACGCAGCGTGGTTACTGGGTTTGCGT
TGGCACTTTGTTGGCATTCTGTTGGCACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025008.1\|WP_004151303.1\|4117931_4118126_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025008.1\|WP_004151291.1\|4110844_4111492_-\|DUF551-domain-containing-protein	unknown	unknown	gnl\|CDD\|367946
NZ_CP025008.1\|WP_004151305.1\|4118514_4119360_+\|phage-recombination-protein-Bet	unknown	unknown	gnl\|CDD\|273871
NZ_CP025008.1\|WP_004151308.1\|4120033_4120192_+\|DUF1317-family-protein	unknown	unknown	gnl\|CDD\|284449
NZ_CP025008.1\|WP_001548453.1\|4115953_4116175_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|336083
NZ_CP025008.1\|WP_004151287.1\|4109718_4109889_-\|NinE-family-protein	unknown	unknown	gnl\|CDD\|182029
NZ_CP025008.1\|WP_004151300.1\|4116576_4117266_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP025008.1\|WP_004151285.1\|4108956_4109094_-\|YlcG-family-protein	unknown	unknown	unknown
NZ_CP025008.1\|WP_004151288.1\|4109888_4110344_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182057
NZ_CP025008.1\|WP_004151301.1\|4117616_4117832_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025008.1\|WP_004151299.1\|4116215_4116449_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NZ_CP025008.1\|WP_004151306.1\|4119356_4120037_+\|YqaJ-viral-recombinase-family-protein	unknown	unknown	gnl\|CDD\|378216
NZ_CP025008.1\|WP_004151294.1\|4112613_4113120_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025008.1\|WP_004151295.1\|4113116_4113410_-\|protein-ren	unknown	unknown	gnl\|CDD\|238042
NZ_CP025008.1\|WP_004151286.1\|4109090_4109726_-\|protein-ninG	unknown	unknown	gnl\|CDD\|368603
NZ_CP025008.1\|WP_004151284.1\|4108433_4108964_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|379158
NZ_CP025008.1\|WP_004151293.1\|4111664_4112507_-\|translation-repressor-RelE	unknown	unknown	gnl\|CDD\|379401
NZ_CP025008.1\|WP_004151304.1\|4118214_4118499_+\|host-nuclease-inhibitor-GamL	unknown	unknown	unknown
NZ_CP025008.1\|WP_004151310.1\|4120188_4120845_+\|DNA-methyltransferase	unknown	unknown	gnl\|CDD\|227069
NZ_CP025008.1\|WP_004151296.1\|4113409_4114840_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672

Protein	Function_ID	Function_description	E-value
NZ_CP025008.1\|WP_004151291.1\|4110844_4111492_-\|DUF551-domain-containing-protein	gnl\|CDD\|367946	pfam04448, DUF551, Protein of unknown function (DUF551). This family represents the carboxy terminus of a protein of unknown function, found in dsDNA viruses with no RNA stage, including bacteriophages lambda and P22, and also in some Escherichia coli prophages.	8.71432e-11
NZ_CP025008.1\|WP_004151305.1\|4118514_4119360_+\|phage-recombination-protein-Bet	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	3.75286e-34
NZ_CP025008.1\|WP_004151308.1\|4120033_4120192_+\|DUF1317-family-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	3.35548e-20
NZ_CP025008.1\|WP_001548453.1\|4115953_4116175_-\|hypothetical-protein	gnl\|CDD\|336083	pfam05269, Phage_CII, Bacteriophage CII protein. This family consists of several phage CII regulatory proteins. CII plays a key role in the lysis-lysogeny decision in bacteriophage lambda and related phages.	1.55058e-09
NZ_CP025008.1\|WP_004151287.1\|4109718_4109889_-\|NinE-family-protein	gnl\|CDD\|182029	PRK09689, PRK09689, prophage protein NinE; Provisional.	1.47696e-19
NZ_CP025008.1\|WP_004151300.1\|4116576_4117266_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	1.58097e-27
NZ_CP025008.1\|WP_004151306.1\|4119356_4120037_+\|YqaJ-viral-recombinase-family-protein	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	1.68114e-32
NZ_CP025008.1\|WP_004151288.1\|4109888_4110344_-\|hypothetical-protein	gnl\|CDD\|182057	PRK09741, PRK09741, hypothetical protein; Provisional.	1.50704e-78
NZ_CP025008.1\|WP_004151299.1\|4116215_4116449_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	9.32854e-22
NZ_CP025008.1\|WP_004151295.1\|4113116_4113410_-\|protein-ren	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	0.000668668
NZ_CP025008.1\|WP_004151286.1\|4109090_4109726_-\|protein-ninG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	9.44908e-60
NZ_CP025008.1\|WP_004151284.1\|4108433_4108964_-\|HNH-endonuclease	gnl\|CDD\|379158	pfam13392, HNH_3, HNH endonuclease. This is a zinc-binding loop of Fold group 7 as found in endo-deoxy-ribonucleases and HNH nucleases.	8.84074e-15
NZ_CP025008.1\|WP_004151293.1\|4111664_4112507_-\|translation-repressor-RelE	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	0.000117969
NZ_CP025008.1\|WP_004151310.1\|4120188_4120845_+\|DNA-methyltransferase	gnl\|CDD\|227069	COG4725, IME4, Transcriptional activator, adenine-specific DNA methyltransferase [Signal transduction mechanisms / Transcription].	6.42213e-22
NZ_CP025008.1\|WP_004151296.1\|4113409_4114840_-\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	7.87266e-159

>NZ_CP025008.1|WP_004151296.1|4113409_4114840_-|AAA-family-ATPase
MTSDFMTPPHSIEAEQSVLGGLLLDDDNSERTQKVLSILKPESFYARPHQVIFAEMRQMYRDHKPVDLLTLFDALESKGLTETVGGFAYLAEMSKNTPSAANIVAYAMRVRETAMERYGIEKTTKAIELLYARNGMTAEQKFDAIQGLFTEITEHVKTGRRTGLRTFYDAVTDWSAEFDERLKPDGRSRGLSTGIRSLDELLGVKRIVRGSLFVIGARPKMGKTTLYTQMGINCATVENEPALMFSLEMPEGQMVEKITAQKGRISPNLFYPDMTKDDYGYRGDWNSDLQKATGVMGALIETNNLLIDDTPGISLAHVMAESRRIKRERGKVGMILVDYLTLMTADKAERNDLAYGLITKGLKILAKELDCVVVLLTQLNRDLEKRTNKRPLPSDSRDTGQIEQDCDYWLAIYREGAYDENANQSDTELLLRLNRHGETGVVYCEQRHGAIYDCDQEAASQRRREKEQKPTKRGGF
>NZ_CP025008.1|WP_004151295.1|4113116_4113410_-|protein-ren
MTGKDAILNYLKTHKTCSSPDVAAASGMTHTCINQAANILAKQGVLVAEARVWRTVYYRLATEEEIAGRKSTNQIFNECRQSPAMKRVLAVYGRTSA
>NZ_CP025008.1|WP_004151294.1|4112613_4113120_-|hypothetical-protein
MTITLQAVNKLIASMESAGELSIREQKFLKLAKEFRICSASLDAAIKTGNMLADQNAQLAAENVALKDINAWCKTDAFKNMYREFKTAEALGCSDADCMHDAMLVAIMHAPATPATDRIVAGIKADGVEEFAAKLRIPGDDQFFDALAKGIALAADDFAKQLREGADK
>NZ_CP025008.1|WP_004151293.1|4111664_4112507_-|translation-repressor-RelE
MTDITELAQSLKAAAEKASNGDWVKESGDGWEACCSANDQANGGFIIAHFVGPDAAENCEFVQAANPANVLALVEALEYYKSREERVTSLVRDNSKSWDELYRQVEAKGKRNVELVEALESEKRICATWRKTAESTSEKLEKAQAAERRWHRVASRVHEQACESDVKIDELEAIRAAAEKLVRCKGRYHSEQNYRALAALFGVNTPDLPPLEHENVHYADAAEMEIEALRQRIAELESRTVKLPPRVDSSNVPFAGNAWNCCLDEVEKRLTAAGIKMEAE
>NZ_CP025008.1|WP_004151291.1|4110844_4111492_-|DUF551-domain-containing-protein
MTNNQLAENSVIQLLNSVKLARDNAELADNRVDHSFYYALTIALEELQERRKAAMDSEPVLWAWHHLDMWHVTSHDGRARDLWLSGFKVIPLYRHAQPVLVIPDEMTAEQAYEIGYYYGDPVDVFARGANWMRQHIIDSTLAAAPQSPGSDPATVPGKWISVSERMPENDGAYLCWDNRYVTTYAFIFGAWQANQFIAKNITHWMPLPAGPQEVR
>NZ_CP025008.1|WP_004151288.1|4109888_4110344_-|hypothetical-protein
MNIPQCGIKLHNGNFSAIGKILQEQLSDGKCLRLQVKEWREKRSLSQNALSHMWYAEISEYLINSGRTDATPEWVKRNLKKTYLGCEEVTYTDFITGEKTTTWEPRHTSDLDTGEMHIFLTKVEAWCAQFGLALTIPHGCEYQQLQQKQEA
>NZ_CP025008.1|WP_004151287.1|4109718_4109889_-|NinE-family-protein
MSSLLAKVIERGIFRVPARRKRKVEDKPSDIPTLKDYTARLVDKKWLRLRARRPHA
>NZ_CP025008.1|WP_004151286.1|4109090_4109726_-|protein-ninG
MRKPARRKCAHCREWFHPAREGQVVCSFECASAIGKKQTAKAREAAKARAVKRQRESEKEGRQRRKARLAELRPNGYYKAQAQKAFNAYIRARDAALPCISCGETNPPDLHGGQWDCGHFKTVGAYPELRFEERNAHKQCKSCNAGAGKYTAKELTVAQQYEAGLVARYGQEYVDWLNGPHEMTNYRREDFIRIRDEYRAKLKALKQREAA
>NZ_CP025008.1|WP_004151285.1|4108956_4109094_-|YlcG-family-protein
MNHDIIERIRDRWKKLRLLRSRGTVLVDYLILRNFIASLSRGSYE
>NZ_CP025008.1|WP_004151284.1|4108433_4108964_-|HNH-endonuclease
MSKSEKSITQELLRTLLEYDPQTGIFRWKIKASSSAHPGDIAGCIDGQGYRVIRIYGKNRKAHRLAWLYVYGDEPEVIDHIDRNRSNNAIENLRAVTFSQNSANRAAKSKNKSGFTGVYWNELGKKWQASIVANGRTHYVGLFATAQEAAKARTEYARQLYANFYIPSFHDQEAAK
>NZ_CP025008.1|WP_001548453.1|4115953_4116175_-|hypothetical-protein
MESSTTRNKVEARRIESWLHSQIAELGTTNIAKVAGVNKSTVSRWRESLLPNMSLLLAILISNRPGEKGDFEA
>NZ_CP025008.1|WP_004151299.1|4116215_4116449_-|helix-turn-helix-domain-containing-protein
MKNPAVEKAISIAGSQKELAKRCGKAQSTICDWLNGKKRISPVHVPDLVAAVNGEIKAYEFRPDLPSIFPPPNNSAA
>NZ_CP025008.1|WP_004151300.1|4116576_4117266_+|helix-turn-helix-transcriptional-regulator
MDFSERLARAMSLAGYTQGRLAKEVGMAQSSVNKLLNGANGSRKTVEIASVLGVRPEWLSTGAGEMLADSIQITQMQTPVTPQNGIYRVDVLDVKASAGPGALITNDFIETIRAIEYTSEQARSLFGNRPAHHIKVITVTGDSMDTTISPGDEIFVDISSTHFDSDGVYVFVFGKTLHVKRLQMQRDRLAVISDNPIYEKWYVEPGDEDQFYVMARVLLRQSIEYKRFA
>NZ_CP025008.1|WP_004151301.1|4117616_4117832_+|hypothetical-protein
MSKENNGGPAYPTQGYEGLTVRDYFAAKAMQGWLAGYPAGINHPARSEEGFTVAELSYLMADAMLKAREEV
>NZ_CP025008.1|WP_004151303.1|4117931_4118126_+|hypothetical-protein
MANSIPNNGRAVMMRNRRTGAAWLVSFDYRDGSYWHEPQGNLRHIRRPYASRSIEPNLVPAGTH
>NZ_CP025008.1|WP_004151304.1|4118214_4118499_+|host-nuclease-inhibitor-GamL
MNAYRAYDVIEERKWAEQTLTEEKQKWIEDRAKEVFDSLPEDPYAALRQSVSSKSFPYEGLRSDKAGEVYNDLRTAIAYAQAEYDWDHRTGCPF
>NZ_CP025008.1|WP_004151305.1|4118514_4119360_+|phage-recombination-protein-Bet
MANELVITASSLAERGIDGATWSALKNSIYPGAKDESVMMALDYCRARNLDPLLKPVHLVPMSVKDSKSGKSEWRDVVMPGIGLYRIQADRSGDYAGAKEPEFGPDVTLTLTGIEVTVPQWCKYTVSKRMPSGEIVEFSAKEYWVENYATAGRDTTAPNAMWKKRPYGQLAKCAEAQALRKAWPEIGQQPTAEEMEGKTLEVDARDVTPRSTPEAPPLVASEETLQAITDLLTSLNKDWEQDFLPLCSNIFKRDIFQASQLTEEEAQKGFSFLQKKAQVAA
>NZ_CP025008.1|WP_004151306.1|4119356_4120037_+|YqaJ-viral-recombinase-family-protein
MTPEIILERTGIDVTRVEQGDESWHRLRLGVITASEVHNVISKPKSGKKWTDMKMSYFLTLLAEVCTGVAPEVNAKALAWGKQYEADARTLFEFTTDVKVTESPILFRDEGMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQFSMWVTGKDAWYFANYDPRMKREGIHHVVVERDDKYMSDFNEMVPEFISKMDESLAEIGFTFGEQWK
>NZ_CP025008.1|WP_004151308.1|4120033_4120192_+|DUF1317-family-protein
MKHYRDAITVGKVKCMYSVLHRGWLMPSGEVVRNPLKAQRLAEELDTKRGAR
>NZ_CP025008.1|WP_004151310.1|4120188_4120845_+|DNA-methyltransferase
MKRYSLIYADPAWSYGNTISNGAAVDHYPTMSLLDMKRLPVWELAADNAVLAMWYTGTHNQEAIELAEAWGFTVRTMKGFTWVKLNQLAELRITKALAEGDVTDFYDFLALLNAETRMNGGNHTRANTEDVLIATRGAGLERKHAGIKQVVYSPLGAHSEKPWEVRHRLELLYGDVPRIELFSRSAAPGWSHWGNQCATASVELIPGCAIDVVKTEAA

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Crispr_ID: NZ_CP025008_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025008_2

4599193-4599287

Orphan

Consensus_repeat	Method
ACTATGGTTTTTATGGTTTTTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025008_2

>merge|NZ_CP025008|2|4599193-4599287|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATGGTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATGACTGTGGTTTTTATGGTTTTTATT

>NZ_CP025008|2|2|4599193-4599287|CRISPRCasFinder
TTAATGGTCACTATGGTTTTTATG	GTTTTTATTCGCTGAACTGCCCGGGAGTGATATATCTCTGATTTATG
ACTGTGGTTTTTATGGTTTTTATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025008.1\|WP_002888340.1\|4599428_4601054_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP025008.1\|WP_002888337.1\|4601043_4601742_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP025008.1\|WP_002888347.1\|4597020_4597560_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP025008.1\|WP_002888323.1\|4608350_4608728_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP025008.1\|WP_002888320.1\|4609836_4610316_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP025008.1\|WP_002888353.1\|4589951_4590647_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP025008.1\|WP_002888327.1\|4606540_4607530_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP025008.1\|WP_002888329.1\|4605248_4606535_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP025008.1\|WP_002888368.1\|4586591_4588301_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP025008.1\|WP_002888348.1\|4596286_4596946_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP025008.1\|WP_002888357.1\|4588311_4589814_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP025008.1\|WP_002888332.1\|4601774_4602602_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP025008.1\|WP_004147026.1\|4602845_4605194_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP025008.1\|WP_004151368.1\|4593367_4596274_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP025008.1\|WP_002888321.1\|4608732_4609581_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP025008.1\|WP_002888349.1\|4590822_4593180_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP025008.1\|WP_002888370.1\|4585408_4586254_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP025008.1\|WP_002888324.1\|4607526_4608348_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP025008.1\|WP_002888373.1\|4584512_4585280_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP025008.1\|WP_002888345.1\|4597739_4599104_-\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030

Protein	Function_ID	Function_description	E-value
NZ_CP025008.1\|WP_002888340.1\|4599428_4601054_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	6.55037e-173
NZ_CP025008.1\|WP_002888337.1\|4601043_4601742_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	5.03078e-66
NZ_CP025008.1\|WP_002888347.1\|4597020_4597560_-\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
NZ_CP025008.1\|WP_002888323.1\|4608350_4608728_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74
NZ_CP025008.1\|WP_002888320.1\|4609836_4610316_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
NZ_CP025008.1\|WP_002888353.1\|4589951_4590647_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP025008.1\|WP_002888327.1\|4606540_4607530_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP025008.1\|WP_002888329.1\|4605248_4606535_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP025008.1\|WP_002888368.1\|4586591_4588301_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP025008.1\|WP_002888348.1\|4596286_4596946_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	2.4454e-161
NZ_CP025008.1\|WP_002888357.1\|4588311_4589814_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP025008.1\|WP_002888332.1\|4601774_4602602_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
NZ_CP025008.1\|WP_004147026.1\|4602845_4605194_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP025008.1\|WP_004151368.1\|4593367_4596274_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP025008.1\|WP_002888321.1\|4608732_4609581_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP025008.1\|WP_002888349.1\|4590822_4593180_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP025008.1\|WP_002888370.1\|4585408_4586254_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP025008.1\|WP_002888324.1\|4607526_4608348_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
NZ_CP025008.1\|WP_002888373.1\|4584512_4585280_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP025008.1\|WP_002888345.1\|4597739_4599104_-\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169

>NZ_CP025008.1|WP_002888345.1|4597739_4599104_-|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP025008.1|WP_002888347.1|4597020_4597560_-|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>NZ_CP025008.1|WP_002888348.1|4596286_4596946_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPKQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP025008.1|WP_004151368.1|4593367_4596274_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESIDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAGIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP025008.1|WP_002888349.1|4590822_4593180_+|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPNPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLIEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSHVNAWWAQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP025008.1|WP_002888353.1|4589951_4590647_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP025008.1|WP_002888357.1|4588311_4589814_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATVEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP025008.1|WP_002888368.1|4586591_4588301_+|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSKAALTH
>NZ_CP025008.1|WP_002888370.1|4585408_4586254_-|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVREACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP025008.1|WP_002888373.1|4584512_4585280_-|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR
>NZ_CP025008.1|WP_002888340.1|4599428_4601054_+|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEAHDAS
>NZ_CP025008.1|WP_002888337.1|4601043_4601742_+|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSDREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP025008.1|WP_002888332.1|4601774_4602602_-|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP025008.1|WP_004147026.1|4602845_4605194_+|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP025008.1|WP_002888329.1|4605248_4606535_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP025008.1|WP_002888327.1|4606540_4607530_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP025008.1|WP_002888324.1|4607526_4608348_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP025008.1|WP_002888323.1|4608350_4608728_+|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP025008.1|WP_002888321.1|4608732_4609581_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP025008.1|WP_002888320.1|4609836_4610316_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP025008_1	1.1\|4115270\|36\|NZ_CP025008\|CRISPRCasFinder	4115270-4115305	36	MK448233	Klebsiella phage ST11-VIM1phi8.1, complete genome	8447-8482	1.0
NZ_CP025008_1	1.1\|4115270\|36\|NZ_CP025008\|CRISPRCasFinder	4115270-4115305	36	MK448235	Klebsiella phage ST512-KPC3phi13.1, complete genome	8447-8482	1.0
NZ_CP025008_1	1.1\|4115270\|36\|NZ_CP025008\|CRISPRCasFinder	4115270-4115305	36	MK448231	Klebsiella phage ST101-KPC2phi6.1, complete genome	11383-11418	1.0

1. spacer 1.1|4115270|36|NZ_CP025008|CRISPRCasFinder matches to MK448233 (Klebsiella phage ST11-VIM1phi8.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

2. spacer 1.1|4115270|36|NZ_CP025008|CRISPRCasFinder matches to MK448235 (Klebsiella phage ST512-KPC3phi13.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

3. spacer 1.1|4115270|36|NZ_CP025008|CRISPRCasFinder matches to MK448231 (Klebsiella phage ST101-KPC2phi6.1, complete genome) position: , mismatch: 0, identity: 1.0

cctcgccggtacgcagcgtggttactgggtttgcgt	CRISPR spacer
cctcgccggtacgcagcgtggttactgggtttgcgt	Protospacer
************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

446326 : 479583

uncultured_Caudovirales_phage(73.33%)

portal,tail,integrase,protease,terminase,capsid,tRNA,head

attL 463933:463950|attR 479928:479945

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002919147.1\|446326_447274_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	2.2e-07	37.2
WP_002919144.1\|447288_447798_-	peptide deformylase	E3SLL2	Synechococcus_phage	2.6e-18	40.3
WP_002919139.1\|447926_449051_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_002919137.1\|449022_449496_+	DUF494 domain-containing protein	NA	NA	NA	NA
WP_004145330.1\|449521_450064_+	hypothetical protein	NA	NA	NA	NA
WP_002919132.1\|450068_450641_+	L-threonylcarbamoyladenylate synthase type 1 TsaC	NA	NA	NA	NA
WP_002919126.1\|450644_451463_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_002919125.1\|451459_451717_+	DUF1488 domain-containing protein	NA	NA	NA	NA
WP_002919123.1\|451692_452247_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_002919103.1\|458041_458263_-	membrane protein	NA	NA	NA	NA
WP_002919102.1\|458556_461667_-	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_002919101.1\|461679_462819_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004150972.1\|463197_463848_+	acrEF/envCD operon transcriptional regulator	NA	NA	NA	NA
463933:463950	attL	NA	NA	NA	NA
WP_004150971.1\|464123_465350_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.8e-150	62.2
WP_004150970.1\|465442_466384_+	hypothetical protein	NA	NA	NA	NA
WP_001547839.1\|466565_466850_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_004150969.1\|466860_467640_+	hypothetical protein	Q8HA02	Enterobacteria_phage	6.2e-40	51.5
WP_106918304.1\|468091_468361_+	host cell division inhibitor Icd-like protein	A0A2H4JGW3	uncultured_Caudovirales_phage	2.4e-44	94.4
WP_001549752.1\|468353_468542_+	hypothetical protein	NA	NA	NA	NA
WP_004150967.1\|468534_468849_+	hypothetical protein	NA	NA	NA	NA
WP_004150966.1\|468845_469214_+	hypothetical protein	A0A2H4JCX7	uncultured_Caudovirales_phage	3.7e-51	81.1
WP_001549749.1\|469210_469576_+	hypothetical protein	NA	NA	NA	NA
WP_004150965.1\|469575_471711_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	3.4e-205	62.4
WP_004150964.1\|472053_472389_+	hypothetical protein	NA	NA	NA	NA
WP_004150963.1\|472437_472950_-	hypothetical protein	NA	NA	NA	NA
WP_001549743.1\|473213_474380_+\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	9.8e-207	95.9
WP_001547826.1\|474431_474992_+\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.2e-98	95.7
WP_004150962.1\|474993_476235_+\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	1.0e-230	96.5
WP_004150961.1\|476231_476567_+\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	3.7e-26	57.8
WP_001547824.1\|476563_476863_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	3.4e-39	80.8
WP_004150959.1\|476862_477306_+	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	2.8e-77	91.8
WP_000113647.1\|477581_477938_+\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	5.5e-60	99.2
WP_004150955.1\|477921_479583_+\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	0.0e+00	98.0
479928:479945	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1342912 : 1396480

Salmonella_phage(41.67%)

tail,integrase,terminase,capsid,tRNA,holin

attL 1331657:1331672|attR 1399408:1399423

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1331657:1331672	attL	NA	NA	NA	NA
WP_004149335.1\|1342912_1344187_+\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_002913890.1\|1344221_1344842_+	YfgM family protein	NA	NA	NA	NA
WP_002913889.1\|1344852_1346031_+	outer membrane protein assembly factor BamB	NA	NA	NA	NA
WP_002913888.1\|1346144_1347623_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_004151982.1\|1347740_1348820_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_004144303.1\|1348869_1349088_+	hypothetical protein	NA	NA	NA	NA
WP_004151981.1\|1349071_1350463_-	exodeoxyribonuclease VII large subunit	A0A2H4UVM9	Bodo_saltans_virus	6.3e-35	33.0
WP_004151980.1\|1350621_1352088_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	1.2e-87	38.7
WP_004151979.1\|1352155_1353733_+	glutamine-hydrolyzing GMP synthase	NA	NA	NA	NA
WP_004243821.1\|1353924_1355175_+\|integrase	tyrosine-type recombinase/integrase	A0A1X9TCT6	Enterobacter_phage	1.8e-206	85.1
WP_004243823.1\|1355191_1355383_-	hypothetical protein	NA	NA	NA	NA
WP_004243826.1\|1355379_1355973_-	adenine methylase	T1SA14	Salmonella_phage	2.1e-109	91.9
WP_004243831.1\|1355969_1356719_-	hypothetical protein	R9VWB9	Serratia_phage	3.1e-73	56.1
WP_004243833.1\|1356715_1356874_-	DUF1317 family protein	T1SAR0	Salmonella_phage	2.5e-17	80.4
WP_004243834.1\|1356866_1357160_-	PerC family transcriptional regulator	T1S9J5	Salmonella_phage	1.2e-31	70.1
WP_004144294.1\|1357269_1357518_-	AlpA family phage regulatory protein	A0A0F6TJ45	Escherichia_coli_O157_typing_phage	2.8e-31	78.0
WP_004243835.1\|1357566_1358448_-	recombinase RecT	T1SBJ5	Salmonella_phage	1.7e-131	82.3
WP_004243836.1\|1358444_1359266_-	exonuclease VIII/RecE-like protein	A0A193GYK2	Enterobacter_phage	8.1e-131	80.2
WP_004243838.1\|1359262_1359562_-	hypothetical protein	A0A0F6R7M4	Escherichia_coli_O157_typing_phage	1.8e-19	53.5
WP_042651015.1\|1359569_1360472_-	hypothetical protein	A0A059VK18	Pseudomonas_phage	2.8e-36	51.6
WP_004152539.1\|1360884_1361466_-	helix-turn-helix transcriptional regulator	Q858D7	Salmonella_phage	1.9e-65	64.8
WP_004152538.1\|1361619_1361853_+	hypothetical protein	T1SAR5	Salmonella_phage	9.2e-24	66.2
WP_004152537.1\|1361999_1362209_+	hypothetical protein	A0A193GYW4	Enterobacter_phage	1.8e-26	78.3
WP_004207253.1\|1362208_1362976_+	hypothetical protein	A0A193GZ86	Enterobacter_phage	8.9e-140	91.4
WP_004152535.1\|1362972_1363758_+	replication protein	A0A193GYX1	Enterobacter_phage	8.2e-133	87.4
WP_004152534.1\|1363877_1364225_+	DUF1064 domain-containing protein	A0A0F6R8N5	Escherichia_coli_O157_typing_phage	5.0e-50	82.6
WP_004152532.1\|1364417_1364828_+	hypothetical protein	A0A2P1MXC5	Escherichia_phage	3.1e-14	42.2
WP_004152531.1\|1364811_1365003_+	hypothetical protein	NA	NA	NA	NA
WP_004152530.1\|1364999_1365425_+	hypothetical protein	NA	NA	NA	NA
WP_004152529.1\|1365421_1366165_+	hypothetical protein	A6N3G8	Burkholderia_virus	1.5e-19	59.5
WP_004141386.1\|1366335_1366548_+	hypothetical protein	A0A0F6TJE4	Escherichia_coli_O157_typing_phage	8.1e-11	45.5
WP_004152527.1\|1366544_1367213_+	DUF551 domain-containing protein	Q6UAT8	Klebsiella_phage	1.5e-05	52.5
WP_004152526.1\|1367205_1367445_+	hypothetical protein	G8C7S3	Escherichia_phage	4.6e-10	48.0
WP_004152525.1\|1367444_1367783_+	hypothetical protein	A0A193GYX4	Enterobacter_phage	4.7e-45	80.0
WP_004152524.1\|1367857_1368115_+	hypothetical protein	NA	NA	NA	NA
WP_004152523.1\|1368192_1368777_+\|terminase	terminase small subunit	T1SBI8	Salmonella_phage	2.4e-89	88.1
WP_020314691.1\|1368773_1370249_+	hypothetical protein	Q858H3	Salmonella_phage	3.2e-279	92.7
WP_004152473.1\|1370292_1370814_-	DUF2829 domain-containing protein	A0A1B0VMG3	Pseudomonas_phage	7.8e-47	55.2
WP_004152472.1\|1371519_1371723_+	hypothetical protein	NA	NA	NA	NA
WP_004152471.1\|1371726_1373406_+\|tail	tail protein	T1S9Z7	Salmonella_phage	3.4e-192	58.9
WP_004152470.1\|1373402_1373708_+	hypothetical protein	Q2A090	Sodalis_phage	1.1e-16	51.3
WP_004152468.1\|1373989_1374388_+	peptidase	T1SAP9	Salmonella_phage	5.6e-37	59.5
WP_004152467.1\|1374400_1375408_+\|capsid	phage capsid protein	T1S9H9	Salmonella_phage	2.7e-181	92.5
WP_004152466.1\|1375417_1375810_+	hypothetical protein	T1SA71	Salmonella_phage	1.5e-55	89.9
WP_004152465.1\|1375802_1376081_+	hypothetical protein	T1SA01	Salmonella_phage	6.7e-21	58.9
WP_004153043.1\|1376129_1376741_+	hypothetical protein	T1SAQ2	Salmonella_phage	1.2e-46	48.8
WP_004152463.1\|1376740_1379218_+	hypothetical protein	G9L6D0	Escherichia_phage	3.6e-267	56.5
WP_004243848.1\|1379219_1379690_+	hypothetical protein	Q858G2	Salmonella_phage	5.0e-45	55.9
WP_004243851.1\|1379682_1380180_+	hypothetical protein	A0A0F6TJ56	Escherichia_coli_O157_typing_phage	7.5e-23	41.7
WP_004243852.1\|1380192_1382937_+	hypothetical protein	A0A193GYI3	Enterobacter_phage	1.2e-93	39.2
WP_004243853.1\|1382936_1386326_+	hypothetical protein	G9L6D4	Escherichia_phage	6.3e-121	42.0
WP_004152458.1\|1386335_1386950_+	hypothetical protein	NA	NA	NA	NA
WP_004152457.1\|1387224_1387623_-	hypothetical protein	NA	NA	NA	NA
WP_004152456.1\|1387627_1387810_-	hypothetical protein	NA	NA	NA	NA
WP_004152455.1\|1388000_1388696_-	hypothetical protein	A0A193GYJ9	Enterobacter_phage	4.4e-61	52.7
WP_004152454.1\|1389076_1389274_-	type II toxin-antitoxin system HicA family toxin	A0A0M4RCZ9	Salmonella_phage	2.0e-19	69.8
WP_004152453.1\|1389277_1389535_-	DUF1902 domain-containing protein	A0A0M4R2Z9	Salmonella_phage	2.3e-12	54.1
WP_002913857.1\|1390073_1392335_+\|tail	tail fiber protein	A0A0A8J9V7	Klebsiella_phage	3.7e-69	35.8
WP_004146394.1\|1392597_1393002_+	membrane protein	T1SA79	Salmonella_phage	9.3e-56	84.1
WP_002913854.1\|1392988_1393294_+\|holin	phage holin family protein	A0A193GYK3	Enterobacter_phage	1.6e-39	82.4
WP_002913853.1\|1393283_1393913_+	glycoside hydrolase family 19 protein	Q858F0	Salmonella_phage	1.8e-90	76.9
WP_002913851.1\|1393909_1394392_+	DUF2514 domain-containing protein	Q858E9	Salmonella_phage	2.8e-59	76.9
WP_004152009.1\|1394611_1396480_-	sulfatase-like hydrolase/transferase	A0A2P0VMN7	Tetraselmis_virus	2.6e-07	22.6
1399408:1399423	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1725204 : 1732111

Planktothrix_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004175147.1\|1725204_1726068_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5
WP_002912638.1\|1726078_1726852_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-25	36.3
WP_002912636.1\|1727094_1727988_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
WP_002912635.1\|1728233_1729595_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	2.5e-206	94.5
WP_002912634.1\|1729913_1730636_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	6.4e-31	33.2
WP_004151135.1\|1730632_1732111_-	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	1.1e-29	28.3

DBSCAN-SWA_4

2074201 : 2130687

Staphylococcus_phage(16.67%)

protease,plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002910830.1\|2074201_2074948_+\|protease	proteasome-type protease	NA	NA	NA	NA
WP_004199384.1\|2075359_2076373_+	fatty acid desaturase	NA	NA	NA	NA
WP_004151439.1\|2076365_2077166_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_002910767.1\|2077152_2077326_-	hypothetical protein	NA	NA	NA	NA
WP_002910764.1\|2077943_2078885_+	transcriptional regulator TdcA	NA	NA	NA	NA
WP_002910762.1\|2078978_2079968_+	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA	NA	NA	NA
WP_004145486.1\|2079993_2081325_+	threonine/serine transporter TdcC	NA	NA	NA	NA
WP_002910759.1\|2081352_2082561_+	propionate kinase	NA	NA	NA	NA
WP_004152312.1\|2082589_2084884_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	2.3e-159	41.8
WP_004219578.1\|2085314_2086430_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002910727.1\|2086539_2087454_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_002910725.1\|2087463_2088741_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_002910722.1\|2088737_2089613_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	9.5e-05	41.5
WP_002910721.1\|2089609_2090329_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.5e-11	26.0
WP_002910720.1\|2090334_2091228_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002910719.1\|2091511_2093155_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	9.8e-136	50.4
WP_002910717.1\|2093204_2093681_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002910715.1\|2093779_2094706_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004152313.1\|2095009_2096305_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.3e-61	36.8
WP_004152314.1\|2096319_2097126_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004152315.1\|2097100_2098000_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002910657.1\|2098109_2098592_-	cold shock domain-containing protein	NA	NA	NA	NA
WP_002910654.1\|2098782_2099481_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	2.6e-05	27.2
WP_004899028.1\|2099506_2100091_-	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_002910650.1\|2100160_2100490_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_002910647.1\|2100576_2100822_+	hypothetical protein	NA	NA	NA	NA
WP_002910645.1\|2101058_2102399_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004152316.1\|2102395_2103049_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004152317.1\|2103052_2104750_+	OmpA family protein	NA	NA	NA	NA
WP_004152319.1\|2107713_2109069_+	hypothetical protein	NA	NA	NA	NA
WP_002910593.1\|2109069_2109579_+	hypothetical protein	NA	NA	NA	NA
WP_002910591.1\|2109575_2110082_+	hypothetical protein	NA	NA	NA	NA
WP_002910586.1\|2110318_2110828_+	hypothetical protein	NA	NA	NA	NA
WP_004153456.1\|2112478_2113402_+\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	1.6e-172	97.1
WP_004199326.1\|2113543_2113726_+	hypothetical protein	NA	NA	NA	NA
WP_004153085.1\|2113722_2114052_+	hypothetical protein	NA	NA	NA	NA
WP_002910551.1\|2114048_2114555_+	hypothetical protein	NA	NA	NA	NA
WP_002910549.1\|2114600_2114831_+	hypothetical protein	NA	NA	NA	NA
WP_004155011.1\|2114936_2116046_+	hypothetical protein	NA	NA	NA	NA
WP_002910547.1\|2116069_2116375_+	hypothetical protein	NA	NA	NA	NA
WP_002910544.1\|2116396_2117290_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7H6	Microcystis_virus	6.7e-14	30.5
WP_004152633.1\|2117473_2118367_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	1.7e-12	27.3
WP_002910539.1\|2118542_2119436_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A075BSL8	Microcystis_phage	2.8e-12	27.1
WP_004152632.1\|2119611_2120502_+	SUMF1/EgtB/PvdO family nonheme iron enzyme	A0A7H6	Microcystis_virus	4.1e-11	29.8
WP_000019473.1\|2120838_2121819_+\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_029779706.1\|2121942_2122179_+	hypothetical protein	NA	NA	NA	NA
WP_004227463.1\|2122367_2122625_+	hypothetical protein	NA	NA	NA	NA
WP_002910497.1\|2122922_2123189_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_004198077.1\|2123192_2124350_+	hypothetical protein	NA	NA	NA	NA
WP_004152262.1\|2124333_2127744_+	type VI secretion protein VasK	NA	NA	NA	NA
WP_002910495.1\|2127877_2129641_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002910494.1\|2129640_2130687_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_5

2795539 : 2806413

Escherichia_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004151613.1\|2795539_2798647_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6
WP_004151612.1\|2798701_2799967_+	MFS transporter	NA	NA	NA	NA
WP_001620097.1\|2799997_2801086_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	8.0e-211	100.0
WP_002904006.1\|2801172_2801433_-	hypothetical protein	A0A077SK33	Escherichia_phage	3.5e-40	97.7
WP_004176269.1\|2801730_2802591_+	class A broad-spectrum beta-lactamase SHV-11	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_002210513.1\|2802611_2803373_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_004151610.1\|2803633_2804536_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	7.7e-159	99.3
WP_002210516.1\|2805792_2806413_+	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0

DBSCAN-SWA_6

3033909 : 3073681

uncultured_Caudovirales_phage(35.42%)

transposase,terminase,integrase

attL 3064794:3064808|attR 3070803:3070817

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152576.1\|3033909_3034776_-	hypothetical protein	A0A2H4IYR0	uncultured_Caudovirales_phage	1.9e-34	64.5
WP_004152575.1\|3034775_3035549_-	DUF2612 domain-containing protein	A0A2H4J1A9	uncultured_Caudovirales_phage	2.8e-77	54.4
WP_004152574.1\|3035545_3036742_-	hypothetical protein	A0A0M4RD32	Salmonella_phage	3.9e-158	72.9
WP_004152573.1\|3036741_3037095_-	hypothetical protein	A0A2H4J629	uncultured_Caudovirales_phage	2.3e-50	80.3
WP_004152572.1\|3037096_3037750_-	hypothetical protein	A0A2H4J8H6	uncultured_Caudovirales_phage	1.0e-59	63.5
WP_004152571.1\|3037803_3038370_-	hypothetical protein	NA	NA	NA	NA
WP_004199301.1\|3038412_3038595_-	hypothetical protein	NA	NA	NA	NA
WP_004152570.1\|3038644_3038986_-	hypothetical protein	A0A2H4J1A5	uncultured_Caudovirales_phage	1.8e-23	46.6
WP_004152569.1\|3038985_3040008_-	hypothetical protein	A0A2H4J1B2	uncultured_Caudovirales_phage	9.2e-100	54.2
WP_004152568.1\|3040010_3040313_-	hypothetical protein	A0A2H4J495	uncultured_Caudovirales_phage	2.0e-26	55.2
WP_004152567.1\|3040313_3040913_-	hypothetical protein	A0A2H4J1B3	uncultured_Caudovirales_phage	9.9e-54	57.6
WP_004152566.1\|3040912_3042916_-	lytic transglycosylase domain-containing protein	A0A2H4J9N7	uncultured_Caudovirales_phage	1.2e-247	63.6
WP_004152565.1\|3042905_3043058_-	hypothetical protein	A0A2H4J1A2	uncultured_Caudovirales_phage	7.6e-19	88.0
WP_004152564.1\|3043093_3043519_-	hypothetical protein	A0A2H4J2V6	uncultured_Caudovirales_phage	2.6e-40	63.4
WP_085955245.1\|3043845_3045037_+\|transposase	IS3-like element ISKpn18 family transposase	U5P429	Shigella_phage	3.5e-50	43.5
WP_004152178.1\|3044978_3045269_-	DUF3277 family protein	A0A2H4J619	uncultured_Caudovirales_phage	2.6e-23	85.5
WP_004152177.1\|3045279_3046425_-	DUF3383 domain-containing protein	A0A2H4J8G4	uncultured_Caudovirales_phage	6.3e-166	76.9
WP_004152176.1\|3046428_3046869_-	hypothetical protein	A0A2H4J1A0	uncultured_Caudovirales_phage	1.6e-40	51.7
WP_001116156.1\|3046963_3047350_-	hypothetical protein	A0A2H4J1A4	uncultured_Caudovirales_phage	1.1e-48	78.2
WP_000834982.1\|3047349_3047856_-	hypothetical protein	NA	NA	NA	NA
WP_000113538.1\|3047852_3048272_-	DUF4054 domain-containing protein	A0A0M5M3S2	Salmonella_phage	3.3e-40	60.7
WP_000725700.1\|3048240_3048522_-	hypothetical protein	NA	NA	NA	NA
WP_001132269.1\|3048561_3049503_-	DUF2184 domain-containing protein	A0A2H4J191	uncultured_Caudovirales_phage	1.7e-137	77.1
WP_000528476.1\|3049514_3050009_-	hypothetical protein	A0A2H4JHM9	uncultured_Caudovirales_phage	4.2e-50	62.7
WP_004199270.1\|3050012_3051215_-	DUF2213 domain-containing protein	A0A0M4R5A6	Salmonella_phage	2.6e-106	54.1
WP_004152174.1\|3051266_3051815_-	hypothetical protein	A0A0M4REK0	Salmonella_phage	3.0e-49	56.3
WP_004152173.1\|3051870_3053322_-	DUF1073 domain-containing protein	A0A0M4S6U1	Salmonella_phage	3.8e-192	68.8
WP_004152172.1\|3053559_3054960_-\|terminase	PBSX family phage terminase large subunit	A0A077KAW0	Edwardsiella_phage	9.4e-188	69.0
WP_004152171.1\|3054910_3055663_-	hypothetical protein	A0A077KBY7	Edwardsiella_phage	4.0e-12	66.0
WP_004152170.1\|3055764_3056085_-	hypothetical protein	NA	NA	NA	NA
WP_004153952.1\|3056319_3056709_-	lipase chaperone	A0A192Y6H8	Salmonella_phage	9.4e-21	49.2
WP_004152169.1\|3056705_3057236_-	lysozyme	K7PLY1	Enterobacteria_phage	2.7e-79	77.1
WP_004146526.1\|3057238_3057487_-	hypothetical protein	NA	NA	NA	NA
WP_004152167.1\|3057892_3058675_-	antitermination protein	F1C595	Cronobacter_phage	7.2e-113	76.8
WP_004198239.1\|3058671_3059148_-	hypothetical protein	A0A286N2Q1	Klebsiella_phage	1.8e-90	100.0
WP_004198233.1\|3059144_3060107_-	zinc-binding domain of primase-helicase family protein	A0A286N2Q0	Klebsiella_phage	4.8e-183	99.4
WP_004198228.1\|3060108_3061767_-	DEAD/DEAH box helicase	A0A286N2P9	Klebsiella_phage	0.0e+00	96.0
WP_004152162.1\|3062343_3062565_-	helix-turn-helix transcriptional regulator	A0A286S2C1	Klebsiella_phage	3.0e-32	100.0
WP_004152161.1\|3062662_3063331_+	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	2.4e-125	99.5
WP_004152160.1\|3063501_3063816_+	hypothetical protein	A0A286S1T9	Klebsiella_phage	1.0e-49	100.0
WP_004152159.1\|3063808_3063997_+	hypothetical protein	A0A286S1P8	Klebsiella_phage	4.6e-26	100.0
WP_004152158.1\|3064166_3064532_+	hypothetical protein	A0A286S1Q6	Klebsiella_phage	6.9e-58	99.2
WP_004152157.1\|3064524_3064779_+	hypothetical protein	A0A286SGR4	Klebsiella_phage	3.1e-41	97.6
WP_004177208.1\|3064750_3064969_+	hypothetical protein	A0A286S1P6	Klebsiella_phage	6.6e-32	98.6
3064794:3064808	attL	NA	NA	NA	NA
WP_004152156.1\|3064965_3065391_+	hypothetical protein	A0A286S1S2	Klebsiella_phage	3.5e-53	77.9
WP_004152155.1\|3065387_3065582_+	hypothetical protein	NA	NA	NA	NA
WP_004152154.1\|3065578_3066406_+	hypothetical protein	Q8W654	Enterobacteria_phage	5.5e-111	84.0
WP_004152153.1\|3066510_3067029_+	hypothetical protein	A0A286S1S7	Klebsiella_phage	1.7e-94	98.8
WP_004154298.1\|3067034_3067745_+	DNA-binding protein	A0A286S260	Klebsiella_phage	2.1e-111	88.3
WP_004152151.1\|3067734_3067959_+	hypothetical protein	A0A286S2B3	Klebsiella_phage	3.1e-29	89.2
WP_004152150.1\|3067955_3068168_+	hypothetical protein	A0A286S2B6	Klebsiella_phage	3.4e-33	98.6
WP_004152149.1\|3068164_3068644_+	hypothetical protein	NA	NA	NA	NA
WP_004152148.1\|3068822_3069065_+	hypothetical protein	A0A0M4RTZ2	Salmonella_phage	2.2e-20	73.8
WP_004152147.1\|3069045_3070227_-\|integrase	site-specific integrase	A0A0M4QX09	Salmonella_phage	5.6e-202	84.2
WP_016197745.1\|3070423_3070972_+	DJ-1/PfpI family protein	NA	NA	NA	NA
3070803:3070817	attR	NA	NA	NA	NA
WP_004152145.1\|3071170_3072703_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	1.1e-21	30.0
WP_004152144.1\|3072919_3073681_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-20	32.5

DBSCAN-SWA_7

3106614 : 3166731

Enterobacteria_phage(20.0%)

transposase,tail,integrase,terminase,holin

attL 3106396:3106411|attR 3164037:3164052

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3106396:3106411	attL	NA	NA	NA	NA
WP_002901815.1\|3106614_3107286_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	4.5e-79	59.6
WP_071531199.1\|3107472_3108300_+	FRG domain-containing protein	A0A1S6KZX9	Salmonella_phage	8.4e-19	30.2
WP_002901813.1\|3108375_3109641_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	9.6e-208	82.7
WP_002901812.1\|3109642_3110062_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	1.4e-35	57.5
WP_004152765.1\|3110141_3111626_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004152776.1\|3112523_3112946_-	hypothetical protein	K7P834	Enterobacteria_phage	3.6e-26	45.3
WP_001067855.1\|3113538_3114243_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004152703.1\|3114491_3116435_+	hypothetical protein	A0A286S1P0	Klebsiella_phage	1.1e-37	69.8
WP_004152702.1\|3116676_3117276_+	hypothetical protein	NA	NA	NA	NA
WP_004152700.1\|3117500_3118232_-	hypothetical protein	NA	NA	NA	NA
WP_022644627.1\|3118235_3121190_-	hypothetical protein	A0A286S1P0	Klebsiella_phage	4.2e-44	68.3
WP_004152652.1\|3121266_3124335_-	hypothetical protein	A0A286S259	Klebsiella_phage	0.0e+00	97.5
WP_004152651.1\|3124331_3124712_-	hypothetical protein	A0A286S2A6	Klebsiella_phage	1.8e-72	99.2
WP_004152650.1\|3124721_3125204_-	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	1.7e-80	94.4
WP_004152649.1\|3125384_3125849_-	hypothetical protein	A0A286S298	Klebsiella_phage	6.7e-58	67.8
WP_004152648.1\|3126163_3126499_-	hypothetical protein	NA	NA	NA	NA
WP_000019473.1\|3126689_3127670_-\|transposase	IS5-like element ISKpn26 family transposase	Q38213	Escherichia_phage	8.9e-185	99.1
WP_004217331.1\|3127782_3130680_-\|tail	tail protein	A0A2H4J107	uncultured_Caudovirales_phage	1.6e-104	32.7
WP_099119318.1\|3130941_3131133_-	hypothetical protein	S4TR42	Salmonella_phage	7.8e-05	78.3
WP_004217333.1\|3131357_3131714_-	hypothetical protein	A0A1V0E5P9	Salmonella_phage	1.1e-44	75.0
WP_016831940.1\|3131790_3131997_-	hypothetical protein	NA	NA	NA	NA
WP_004226994.1\|3132134_3132617_-	hypothetical protein	NA	NA	NA	NA
WP_004217341.1\|3132670_3133843_-	Ig domain-containing protein	A0A0D4DBN5	Acinetobacter_phage	1.2e-23	27.0
WP_004190640.1\|3133866_3134259_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_004217343.1\|3134255_3134807_-	hypothetical protein	G8C7Q1	Escherichia_phage	1.3e-28	39.9
WP_004217344.1\|3134808_3135192_-	hypothetical protein	A0A0S2SYG4	Pseudomonas_phage	7.1e-21	45.2
WP_004190646.1\|3135178_3135412_-	hypothetical protein	A0A2H4J0Y9	uncultured_Caudovirales_phage	5.8e-10	47.1
WP_004217346.1\|3135421_3135676_-	hypothetical protein	J9Q7U0	Salmonella_phage	1.0e-20	52.4
WP_004217348.1\|3135677_3136073_-	hypothetical protein	A0A1B1P9F2	Acinetobacter_phage	4.3e-13	38.5
WP_004190653.1\|3136394_3137348_-	Ig domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	5.0e-132	74.4
WP_004217351.1\|3137358_3138144_-	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	1.0e-66	63.9
WP_019405022.1\|3138674_3139787_-	hypothetical protein	I6PD76	Cronobacter_phage	5.6e-111	55.1
WP_004218551.1\|3139770_3141171_-	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	1.1e-127	53.5
WP_004190663.1\|3141170_3142478_-\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	3.6e-149	58.9
WP_004218556.1\|3142455_3143460_-\|terminase	terminase small subunit	Q5QF76	Pseudomonas_virus	1.5e-38	45.5
WP_004218558.1\|3144322_3144568_-	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	4.6e-34	96.3
WP_004190672.1\|3145526_3145802_-	hypothetical protein	A0A286N2Q8	Klebsiella_phage	2.2e-08	72.5
WP_004190674.1\|3145798_3146143_-	hypothetical protein	A0A286N2Q7	Klebsiella_phage	2.0e-38	80.7
WP_004218565.1\|3146139_3146679_-	glycoside hydrolase family 108 protein	A0A286N2Q6	Klebsiella_phage	3.3e-101	98.9
WP_024940884.1\|3146675_3146975_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	4.5e-47	100.0
WP_022644626.1\|3147453_3148500_-\|transposase	IS481-like element ISKpn28 family transposase	A0A0M3LR35	Mannheimia_phage	1.3e-05	21.9
WP_004232548.1\|3148725_3149415_-	antiterminator-like protein	I6PDF8	Cronobacter_phage	2.1e-55	53.1
WP_004218534.1\|3149414_3149555_-	YlcG family protein	NA	NA	NA	NA
WP_004218533.1\|3149551_3150190_-	hypothetical protein	H6WRY9	Salmonella_phage	3.2e-74	69.8
WP_004218532.1\|3150182_3150851_-	serine/threonine protein phosphatase	K7P6H8	Enterobacteria_phage	1.4e-104	78.7
WP_004243010.1\|3150847_3151015_-	NinE family protein	K7P7K0	Enterobacteria_phage	4.6e-09	62.5
WP_004218531.1\|3150995_3151463_-	recombination protein NinB	Q8VNP6	Enterobacteria_phage	3.4e-33	45.8
WP_004218530.1\|3151983_3153012_+	hypothetical protein	NA	NA	NA	NA
WP_004196831.1\|3153219_3153465_-	hypothetical protein	NA	NA	NA	NA
WP_004218528.1\|3153520_3153823_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004201118.1\|3153819_3154668_-	ATP-binding protein	K7PLU3	Enterobacteria_phage	5.1e-88	60.1
WP_004201117.1\|3154664_3155525_-	replication protein	K7PGT1	Enterobacteria_phage	1.0e-59	53.3
WP_001548453.1\|3155610_3155832_-	hypothetical protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_004201115.1\|3155872_3156100_-	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	1.4e-24	77.1
WP_004201113.1\|3156211_3156910_+	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	3.7e-108	84.1
WP_019405077.1\|3156932_3157052_+	hypothetical protein	NA	NA	NA	NA
WP_004201109.1\|3157197_3158274_+	ParA family protein	H2BD62	Pseudomonas_phage	9.1e-58	37.9
WP_004201108.1\|3158355_3158559_-	hypothetical protein	A0A192Y6Q5	Salmonella_phage	3.9e-18	71.6
WP_004135674.1\|3158987_3159182_+	hypothetical protein	NA	NA	NA	NA
WP_004201105.1\|3159270_3159555_+	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	1.1e-39	79.8
WP_004201103.1\|3159570_3160416_+	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	1.8e-69	59.2
WP_088224434.1\|3160412_3160700_+	hypothetical protein	NA	NA	NA	NA
WP_004201102.1\|3160701_3161382_+	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	8.2e-121	91.2
WP_004151898.1\|3161378_3161807_+	hypothetical protein	M9NYX4	Enterobacteria_phage	7.5e-64	80.3
WP_004151899.1\|3161803_3162466_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-105	84.6
WP_004153574.1\|3162673_3163861_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	1.1e-120	52.4
WP_004151901.1\|3164037_3164928_+	peptide ABC transporter permease SapC	NA	NA	NA	NA
3164037:3164052	attR	NA	NA	NA	NA
WP_004140266.1\|3164927_3165920_+	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	3.0e-07	27.2
WP_004140269.1\|3165921_3166731_+	peptide ABC transporter ATP-binding protein SapF	A0A2H4PQG7	Staphylococcus_phage	2.1e-14	28.9

DBSCAN-SWA_8

3543025 : 3635976

Salmonella_phage(56.9%)

tail,plate,portal,integrase,protease,lysis,terminase,capsid,tRNA,head

attL 3598551:3598569|attR 3636051:3636069

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002898139.1\|3543025_3544318_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	7.3e-94	44.7
WP_002898137.1\|3544408_3545752_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	7.3e-81	40.8
WP_002898132.1\|3545760_3546372_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_004150846.1\|3546494_3550748_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	5.2e-88	49.2
WP_000228469.1\|3550883_3551378_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_004141839.1\|3551883_3552879_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	3.3e-62	44.0
WP_002898017.1\|3552993_3554760_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	2.3e-21	25.9
WP_004150847.1\|3554760_3556482_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3
WP_002898014.1\|3556526_3557228_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3557581_3557800_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002896522.1\|3557920_3560200_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_002896520.1\|3560230_3560548_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|3560873_3561095_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_004150848.1\|3561171_3563112_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_002896440.1\|3563108_3564224_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_002896437.1\|3564370_3566029_-	ATP-dependent endonuclease	NA	NA	NA	NA
WP_002896434.1\|3566448_3567144_+	aquaporin Z	NA	NA	NA	NA
WP_004147773.1\|3567259_3568159_+	lysine exporter LysO family protein	NA	NA	NA	NA
WP_002896412.1\|3568302_3569955_+	hydroxylamine reductase	NA	NA	NA	NA
WP_002896410.1\|3569965_3570934_+	NADH oxidoreductase	NA	NA	NA	NA
WP_002896408.1\|3571145_3571580_-	DoxX family protein	NA	NA	NA	NA
WP_002896406.1\|3571731_3573450_+	ubiquinone-dependent pyruvate dehydrogenase	NA	NA	NA	NA
WP_002896404.1\|3573488_3574490_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_002896401.1\|3574500_3575943_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002896399.1\|3576030_3577044_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_002896397.1\|3577040_3577871_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	4.1e-05	31.6
WP_004150851.1\|3577902_3579042_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_002896394.1\|3579919_3580435_+	lipoprotein	NA	NA	NA	NA
WP_002896392.1\|3580661_3581390_+	arginine ABC transporter ATP-binding protein ArtP	G9BWD6	Planktothrix_phage	1.2e-29	37.1
WP_002896390.1\|3581410_3582142_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896386.1\|3582148_3582865_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_004150852.1\|3582864_3583533_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_002896384.1\|3583716_3584448_+	arginine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002896382.1\|3584490_3585963_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	7.9e-28	31.8
WP_002896380.1\|3585959_3586676_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.1e-34	36.9
WP_002896378.1\|3586754_3587882_-	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	A0A2K5B251	Erysipelothrix_phage	1.3e-19	25.6
WP_002896376.1\|3587923_3588412_-	DUF2593 family protein	NA	NA	NA	NA
WP_002896372.1\|3588469_3589315_-	putrescine ABC transporter permease PotI	NA	NA	NA	NA
WP_002896371.1\|3589311_3590265_-	putrescine ABC transporter permease PotH	NA	NA	NA	NA
WP_002896370.1\|3590275_3591409_-	putrescine ABC transporter ATP-binding subunit PotG	G3M9Y6	Bacillus_virus	2.2e-30	34.9
WP_002896368.1\|3591572_3592685_-	spermidine/putrescine ABC transporter substrate-binding protein PotF	NA	NA	NA	NA
WP_002896365.1\|3593033_3593513_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_002896363.1\|3593601_3594504_-	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	2.0e-34	35.3
WP_002896354.1\|3595325_3595613_-	YbjC family protein	NA	NA	NA	NA
WP_002896352.1\|3595815_3596079_+	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	1.6e-27	73.1
WP_002896351.1\|3596085_3596469_-	membrane protein	NA	NA	NA	NA
WP_004179131.1\|3596735_3598421_+	aspartate:alanine antiporter	NA	NA	NA	NA
3598551:3598569	attL	NA	NA	NA	NA
WP_000972391.1\|3598640_3598859_-	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	7.5e-20	69.0
WP_002896225.1\|3598950_3600051_-	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	4.9e-176	87.4
WP_002896224.1\|3600047_3600533_-\|tail	phage tail protein	E5G6Q2	Salmonella_phage	7.2e-63	75.6
WP_002896222.1\|3600529_3603157_-\|tail	phage tail tape measure protein	E5FFG5	Burkholderia_phage	5.6e-117	42.0
WP_002896220.1\|3603149_3603269_-\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.2e-13	87.2
WP_002896204.1\|3603283_3603583_-\|tail	phage tail assembly protein	E5G6P9	Salmonella_phage	3.7e-33	79.0
WP_002896201.1\|3603635_3604151_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	1.3e-81	85.4
WP_002896193.1\|3604160_3605333_-\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.9e-210	93.3
WP_002896191.1\|3605471_3606548_-\|tail	phage tail protein	Q37842	Escherichia_phage	1.2e-25	44.8
WP_002896188.1\|3606577_3606781_-	hypothetical protein	NA	NA	NA	NA
WP_002896186.1\|3606777_3607509_-	hypothetical protein	NA	NA	NA	NA
WP_004152882.1\|3607512_3610464_-	hypothetical protein	A0A2H4N7A3	Pectobacterium_phage	1.2e-06	50.9
WP_004150856.1\|3610465_3611065_-\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	1.3e-58	60.5
WP_002896182.1\|3611057_3611966_-\|plate	baseplate assembly protein	E5G6N8	Salmonella_phage	7.6e-106	66.9
WP_002896179.1\|3611952_3612315_-\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	5.8e-49	84.7
WP_002896177.1\|3612311_3612884_-\|plate	phage baseplate assembly protein V	E5G6N6	Salmonella_phage	4.7e-77	72.3
WP_004150857.1\|3612978_3613671_+	hypothetical protein	NA	NA	NA	NA
WP_002896175.1\|3613667_3614114_-	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.2e-50	71.2
WP_002896172.1\|3614106_3614538_-\|tail	phage tail protein	A0A1S6KZY0	Salmonella_phage	9.9e-64	82.5
WP_002896168.1\|3614633_3615062_-\|lysis	LysB family phage lysis regulatory protein	A0A1S6KZX8	Salmonella_phage	9.6e-51	77.9
WP_002896163.1\|3615058_3615442_-	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	2.1e-17	42.0
WP_002896161.1\|3615446_3615956_-	lysozyme	E5G6N1	Salmonella_phage	2.1e-81	83.4
WP_002896158.1\|3615936_3616152_-	hypothetical protein	E5G6N0	Salmonella_phage	3.6e-30	90.1
WP_002896155.1\|3616155_3616359_-\|tail	tail protein X	A0A1S6KZY4	Salmonella_phage	1.3e-29	88.1
WP_002896151.1\|3616358_3616823_-\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	8.4e-77	89.0
WP_000059191.1\|3616918_3617569_-\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
WP_002895972.1\|3617572_3618631_-\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	1.1e-180	93.1
WP_002895967.1\|3618647_3619481_-\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	6.3e-123	88.8
WP_004150858.1\|3619623_3621390_+\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.0
WP_002895959.1\|3621389_3622415_+\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	7.6e-171	86.7
WP_004199124.1\|3622476_3624219_-	AIPR family protein	NA	NA	NA	NA
WP_000700647.1\|3624494_3625172_-	hypothetical protein	NA	NA	NA	NA
WP_001217575.1\|3625286_3625520_-	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_001154434.1\|3625530_3625719_-	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_004150862.1\|3625872_3628287_-	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.5
WP_004150863.1\|3628283_3629141_-	DNA adenine methylase	E5G6L8	Salmonella_phage	2.0e-156	95.4
WP_000752622.1\|3629137_3629365_-	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	6.0e-36	98.7
WP_004150864.1\|3629364_3629598_-	DUF2732 family protein	E5G6L6	Salmonella_phage	4.1e-32	96.1
WP_000963473.1\|3629665_3630007_-	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	4.6e-56	99.1
WP_000956179.1\|3629970_3630171_-	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	1.6e-32	97.0
WP_000460893.1\|3630178_3630688_-	phage regulatory CII family protein	E5G6L3	Salmonella_phage	5.8e-87	98.8
WP_000188448.1\|3630720_3630942_-	hypothetical protein	NA	NA	NA	NA
WP_004152885.1\|3631087_3631966_+	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.7e-30	39.9
WP_004150866.1\|3631977_3632922_+	hypothetical protein	NA	NA	NA	NA
WP_004152765.1\|3633020_3634505_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-31	35.5
WP_004151720.1\|3634923_3635976_+\|integrase	tyrosine-type recombinase/integrase	A0A218M4I3	Erwinia_phage	1.0e-106	57.0
3636051:3636069	attR	NA	NA	NA	NA

DBSCAN-SWA_9

4081085 : 4126360

Escherichia_phage(26.42%)

lysis,tRNA,integrase,head

attL 4074298:4074344|attR 4123432:4123478

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4074298:4074344	attL	NA	NA	NA	NA
WP_004151249.1\|4081085_4083563_-	MoaD/ThiS family protein	F1C5A7	Cronobacter_phage	2.7e-198	45.6
WP_004151250.1\|4083549_4083945_-	hypothetical protein	F1C5F2	Cronobacter_phage	8.0e-36	54.0
WP_004199076.1\|4083941_4084412_-	hypothetical protein	R9TPR6	Aeromonas_phage	2.5e-28	41.0
WP_004165520.1\|4084411_4084831_-	hypothetical protein	A0A2P1MXB5	Escherichia_phage	1.8e-30	48.5
WP_004151253.1\|4084930_4088377_-	tape measure protein	Q5G8W8	Enterobacteria_phage	1.4e-163	48.6
WP_004151254.1\|4088469_4088973_-	hypothetical protein	NA	NA	NA	NA
WP_004151255.1\|4089100_4089886_-	phage repressor protein	A0A2L1IV39	Escherichia_phage	1.9e-84	59.7
WP_004151256.1\|4089951_4090665_-	hypothetical protein	H6WRU8	Salmonella_phage	3.9e-49	50.2
WP_004151257.1\|4090654_4090825_-	Arc family DNA-binding protein	I6R9A8	Salmonella_phage	6.1e-17	87.0
WP_004151258.1\|4090924_4091284_+	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.8e-16	47.5
WP_004151259.1\|4091300_4091771_-	hypothetical protein	NA	NA	NA	NA
WP_004151260.1\|4092064_4092319_-	hypothetical protein	K7PM89	Enterobacteria_phage	6.7e-20	73.0
WP_004151261.1\|4092321_4093077_-	DNA-binding protein	K7PGT4	Enterobacteria_phage	2.4e-60	51.0
WP_004151262.1\|4093252_4093930_-	hypothetical protein	F1C5E8	Cronobacter_phage	4.8e-73	57.9
WP_004151263.1\|4093982_4094735_-	Ig domain-containing protein	G0ZNE6	Cronobacter_phage	5.8e-43	42.1
WP_004151264.1\|4094803_4095196_-	hypothetical protein	G0ZNE4	Cronobacter_phage	5.1e-35	52.7
WP_004151265.1\|4095192_4095618_-	hypothetical protein	R9TPP7	Aeromonas_phage	5.1e-28	47.9
WP_004151266.1\|4095620_4095983_-	hypothetical protein	A0A173GCE0	Salmonella_phage	1.8e-18	45.0
WP_004151267.1\|4095982_4096156_-	hypothetical protein	I6R0P9	Salmonella_phage	1.4e-13	56.1
WP_004151268.1\|4096155_4096536_-	hypothetical protein	F1C5E2	Cronobacter_phage	5.3e-29	55.3
WP_004151269.1\|4096538_4096778_-	hypothetical protein	NA	NA	NA	NA
WP_004151270.1\|4096788_4097883_-	hypothetical protein	F1C5E1	Cronobacter_phage	1.7e-123	62.8
WP_004151271.1\|4097894_4098323_-	hypothetical protein	F1C5E0	Cronobacter_phage	1.6e-42	60.8
WP_004151272.1\|4098326_4099712_-	DUF2213 domain-containing protein	F1C5D9	Cronobacter_phage	2.3e-154	60.0
WP_004151273.1\|4099784_4100261_-	hypothetical protein	NA	NA	NA	NA
WP_004151274.1\|4100302_4101307_-\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	9.0e-116	69.7
WP_004151275.1\|4101281_4102703_-	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	9.6e-148	57.1
WP_004151276.1\|4102715_4104188_-	hypothetical protein	A0A1W6JNY3	Morganella_phage	1.3e-248	82.5
WP_004151277.1\|4104187_4104790_-	hypothetical protein	G8C7P2	Escherichia_phage	5.4e-76	80.9
WP_004151279.1\|4105160_4105490_+	hypothetical protein	NA	NA	NA	NA
WP_004151280.1\|4105595_4106060_-\|lysis	lysis protein	Q76H63	Enterobacteria_phage	2.4e-55	73.2
WP_004151281.1\|4106056_4106587_-	lysozyme	G9L6J6	Escherichia_phage	6.0e-79	78.5
WP_004151282.1\|4106589_4106838_-	hypothetical protein	NA	NA	NA	NA
WP_004151283.1\|4107747_4108437_-	antitermination protein	I6PDF8	Cronobacter_phage	1.4e-56	54.5
WP_004151284.1\|4108433_4108964_-	HNH endonuclease	A0A193GYW9	Enterobacter_phage	5.2e-30	43.1
WP_004151285.1\|4108956_4109094_-	YlcG family protein	NA	NA	NA	NA
WP_004151286.1\|4109090_4109726_-	protein ninG	M9NYX8	Enterobacteria_phage	2.7e-81	77.9
WP_004151287.1\|4109718_4109889_-	NinE family protein	G8C7V4	Escherichia_phage	1.3e-14	73.2
WP_004151288.1\|4109888_4110344_-	hypothetical protein	K7P7B8	Enterobacteria_phage	8.0e-56	69.5
WP_004151291.1\|4110844_4111492_-	DUF551 domain-containing protein	A5LH60	Enterobacteria_phage	4.5e-12	32.6
WP_004151293.1\|4111664_4112507_-	translation repressor RelE	A0A2H4FRZ0	Salmonella_phage	1.8e-29	60.8
WP_004151294.1\|4112613_4113120_-	hypothetical protein	A0A0A6Z565	Enterobacter_phage	3.0e-27	59.6
WP_004151295.1\|4113116_4113410_-	protein ren	O48423	Enterobacteria_phage	3.3e-26	65.6
WP_004151296.1\|4113409_4114840_-	AAA family ATPase	Q9MCT4	Escherichia_phage	2.6e-185	66.7
WP_004151297.1\|4114829_4115729_-	hypothetical protein	F1C5C3	Cronobacter_phage	5.4e-88	54.9
WP_001548453.1\|4115953_4116175_-	hypothetical protein	G8EYH8	Enterobacteria_phage	6.9e-05	41.7
WP_004151299.1\|4116215_4116449_-	helix-turn-helix domain-containing protein	G8C7U2	Escherichia_phage	4.3e-13	50.7
WP_004151300.1\|4116576_4117266_+	helix-turn-helix transcriptional regulator	G8C7U1	Escherichia_phage	4.3e-61	52.2
WP_004151301.1\|4117616_4117832_+	hypothetical protein	B5WZV1	Pseudomonas_phage	1.6e-09	48.6
WP_004151303.1\|4117931_4118126_+	hypothetical protein	NA	NA	NA	NA
WP_004151304.1\|4118214_4118499_+	host nuclease inhibitor GamL	G8C7T1	Escherichia_phage	8.0e-30	62.8
WP_004151305.1\|4118514_4119360_+	phage recombination protein Bet	A0A1I9KF88	Aeromonas_phage	6.9e-69	59.2
WP_004151306.1\|4119356_4120037_+	YqaJ viral recombinase family protein	A0A0M3ULE0	Salmonella_phage	7.9e-124	93.4
WP_004151308.1\|4120033_4120192_+	DUF1317 family protein	A0A0N7CHV0	Escherichia_phage	3.0e-10	60.8
WP_004151310.1\|4120188_4120845_+	DNA methyltransferase	G8C7S6	Escherichia_phage	2.7e-113	87.5
WP_004151312.1\|4120841_4121609_+	hypothetical protein	D5LH17	Escherichia_phage	1.7e-66	53.4
WP_004151314.1\|4121605_4121824_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.2e-09	47.2
WP_004151316.1\|4121825_4122041_+	TraR/DksA family transcriptional regulator	A0A0K2FI84	Escherichia_phage	4.0e-13	52.9
WP_004151317.1\|4122042_4122378_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_004151318.1\|4122254_4123418_+\|integrase	site-specific integrase	G8C7S0	Escherichia_phage	3.3e-202	87.3
WP_004143017.1\|4123848_4124715_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-30	34.8
4123432:4123478	attR	NA	NA	NA	NA
WP_004143016.1\|4124716_4124929_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_004143010.1\|4124974_4126360_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.5e-46	35.4

DBSCAN-SWA_10

4335897 : 4347551

Enterobacteria_phage(70.0%)

integrase

attL 4336347:4336361|attR 4359404:4359418

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004144574.1\|4335897_4337001_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.8e-62	40.5
4336347:4336361	attL	NA	NA	NA	NA
WP_002889940.1\|4337011_4338265_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	8.9e-89	44.9
WP_002889938.1\|4338617_4339808_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	6.4e-145	62.7
WP_004152029.1\|4339795_4340746_+	cobyrinic acid a,c-diamide synthase	A0A1X9IGI7	Lactococcus_phage	1.2e-13	27.1
WP_004152979.1\|4340745_4341171_+	hypothetical protein	NA	NA	NA	NA
WP_002889930.1\|4341739_4342306_-	phage polarity suppression protein	Q7M2A1	Enterobacteria_phage	1.5e-59	64.3
WP_002889919.1\|4342323_4342569_-	hypothetical protein	Q7M294	Enterobacteria_phage	1.9e-19	58.0
WP_002889917.1\|4342565_4343303_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	9.0e-73	60.7
WP_002889915.1\|4343844_4344111_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	2.6e-30	71.6
WP_024940872.1\|4344107_4344665_+	ash family protein	Q7M2A7	Enterobacteria_phage	1.8e-33	70.4
WP_002889911.1\|4344661_4344889_+	hypothetical protein	NA	NA	NA	NA
WP_002889897.1\|4344885_4345206_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_002889890.1\|4345217_4347551_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	82.2
4359404:4359418	attR	NA	NA	NA	NA

DBSCAN-SWA_11

4815796 : 4823887

Enterobacteria_phage(83.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152207.1\|4815796_4818130_-	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	83.9
WP_004152206.1\|4818144_4818465_-	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_004152205.1\|4818461_4818689_-	hypothetical protein	NA	NA	NA	NA
WP_004153681.1\|4818685_4819234_-	ash family protein	Q7M2A7	Enterobacteria_phage	1.1e-30	69.4
WP_004152204.1\|4820057_4820795_+	hypothetical protein	Q7M2A2	Enterobacteria_phage	1.1e-70	59.4
WP_004152203.1\|4820791_4821037_+	hypothetical protein	Q7M294	Enterobacteria_phage	5.5e-19	56.8
WP_004152202.1\|4821054_4821621_+	phage polarity suppression protein	Q7M2A1	Enterobacteria_phage	9.7e-59	63.8
WP_085956494.1\|4822682_4823887_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	4.8e-100	62.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP025010

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

11308 : 49757

Escherichia_phage(28.57%)

transposase,integrase

attL 47618:47631|attR 50080:50093

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004152342.1\|11308_12577_+\|transposase	ISL3-like element ISKpn25 family transposase	Q6V7R1	Burkholderia_virus	5.2e-60	34.7
WP_004152341.1\|12696_13170_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_011977773.1\|13261_13492_+	hypothetical protein	NA	NA	NA	NA
WP_004152340.1\|14383_15166_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.6e-51	90.2
WP_004152339.1\|15165_15498_-	hypothetical protein	NA	NA	NA	NA
WP_004152338.1\|15504_15861_-	hypothetical protein	NA	NA	NA	NA
WP_004152337.1\|15928_16258_-	hypothetical protein	NA	NA	NA	NA
WP_004152336.1\|16285_16594_-	hypothetical protein	NA	NA	NA	NA
WP_004153649.1\|16639_16846_-	hypothetical protein	NA	NA	NA	NA
WP_001261282.1\|17498_17729_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_001044770.1\|17725_18142_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_004152334.1\|18215_18926_+	AAA family ATPase	NA	NA	NA	NA
WP_072093211.1\|19657_19783_+	mercury transporter	NA	NA	NA	NA
WP_001340589.1\|19818_20241_+	organomercurial transporter MerC	NA	NA	NA	NA
WP_000105636.1\|20292_21987_+	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	8.8e-39	27.6
WP_001277456.1\|22004_22367_+	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_000993386.1\|22363_22600_+	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_000204520.1\|22596_23304_+	EAL domain-containing protein	NA	NA	NA	NA
WP_000935452.1\|23342_24647_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_000027057.1\|25214_26075_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
WP_001067855.1\|27818_28523_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004152403.1\|28595_31493_+\|transposase	Tn3-like element Tn5403 family transposase	A0A1B0V7H9	Salmonella_phage	2.7e-181	37.7
WP_004152402.1\|31581_32202_+	recombinase family protein	A0A219Y912	Aeromonas_phage	2.0e-09	31.5
WP_001143775.1\|32611_35617_-\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	99.3
WP_001217881.1\|35778_36336_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	2.0e-93	98.4
WP_063840280.1\|36569_37124_+	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NA	NA	NA	NA
WP_001067855.1\|37474_38179_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_004152398.1\|38795_39980_+\|transposase	ISAs1-like element ISKpn31 family transposase	NA	NA	NA	NA
WP_004152397.1\|40256_41576_+\|transposase	IS1182-like element ISKpn6 family transposase	Q9MBP7	Staphylococcus_prophage	1.9e-12	24.2
WP_004199234.1\|41825_42707_-	carbapenem-hydrolyzing class A beta-lactamase KPC-2	A0A1B0VBP7	Salmonella_phage	2.2e-73	52.2
WP_004152394.1\|42994_43774_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.5e-89	61.8
WP_004199214.1\|43770_44796_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.4e-87	50.3
WP_004152392.1\|44902_47932_-\|transposase	IS3-like element Tn4401 family transposase	NA	NA	NA	NA
47618:47631	attL	NA	NA	NA	NA
WP_004152391.1\|48041_49757_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_004152391.1\|48041_49757_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
50080:50093	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP025009

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP025008

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP025010

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection