CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018838	Streptococcus pneumoniae strain 11A chromosome, complete genome	3 crisprs	DinG,DEDDh,cas3	0	1	12	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018838_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018838_1

1168178-1168261

Orphan

Consensus_repeat	Method
CTTTTTTGAAACGTTTCATTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018838_1

>merge|NZ_CP018838|1|1168178-1168261|CRISPRCasFinder
CTTTTTTGAAACGTTTCATTTTTTTCTAGAAAAGATAGCGCTTGGCGCTGTCTTTTTATTTCTTTTTTGAAACGTTTCATTTTT

>NZ_CP018838|1|1|1168178-1168261|CRISPRCasFinder
CTTTTTTGAAACGTTTCATTTTT	TTCTAGAAAAGATAGCGCTTGGCGCTGTCTTTTTATTT
CTTTTTTGAAACGTTTCATTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018838.1\|WP_000109957.1\|1173238_1173442_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP018838.1\|WP_000230204.1\|1168317_1169319_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP018838.1\|WP_000502554.1\|1163375_1164695_-\|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl\|CDD\|224536
NZ_CP018838.1\|WP_000064115.1\|1172599_1173208_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP018838.1\|WP_000782431.1\|1175483_1176332_-\|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl\|CDD\|335469
NZ_CP018838.1\|WP_001205280.1\|1169680_1171162_-\|aspartate-aminotransferase	unknown	unknown	gnl\|CDD\|285470
NZ_CP018838.1\|WP_001812322.1\|1174133_1174421_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP018838.1\|WP_000818079.1\|1161051_1161291_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000257097.1\|1159141_1159612_-\|DUF3013-family-protein	unknown	unknown	gnl\|CDD\|337951
NZ_CP018838.1\|WP_000669745.1\|1164704_1166321_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270299
NZ_CP018838.1\|WP_001113216.1\|1161560_1162832_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP018838.1\|WP_000229332.1\|1174698_1175469_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP018838.1\|WP_001844946.1\|1160391_1160598_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP018838.1\|WP_000030213.1\|1171812_1172379_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	unknown	unknown	gnl\|CDD\|380217
NZ_CP018838.1\|WP_000797961.1\|1166349_1167240_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP018838.1\|WP_000961810.1\|1159902_1160355_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NZ_CP018838.1\|WP_001809002.1\|1171564_1171729_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP018838.1\|WP_001809903.1\|1160707_1160887_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_001084979.1\|1167250_1168168_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NZ_CP018838.1\|WP_000455066.1\|1172390_1172561_+\|DUF2273-domain-containing-protein	unknown	unknown	gnl\|CDD\|227834

Protein	Function_ID	Function_description	E-value
NZ_CP018838.1\|WP_000109957.1\|1173238_1173442_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	1.20386e-07
NZ_CP018838.1\|WP_000230204.1\|1168317_1169319_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.86275e-99
NZ_CP018838.1\|WP_000502554.1\|1163375_1164695_-\|glycoside-hydrolase-family-32-protein	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	6.65864e-177
NZ_CP018838.1\|WP_000064115.1\|1172599_1173208_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	1.35166e-33
NZ_CP018838.1\|WP_000782431.1\|1175483_1176332_-\|formylglycine-generating-enzyme-family-protein	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	2.99285e-66
NZ_CP018838.1\|WP_001205280.1\|1169680_1171162_-\|aspartate-aminotransferase	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	1.09342e-73
NZ_CP018838.1\|WP_001812322.1\|1174133_1174421_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.91273e-14
NZ_CP018838.1\|WP_000257097.1\|1159141_1159612_-\|DUF3013-family-protein	gnl\|CDD\|337951	pfam11217, DUF3013, Protein of unknown function (DUF3013). This bacterial family of proteins with unknown function appear to be restricted to Firmicutes.	1.46969e-66
NZ_CP018838.1\|WP_000669745.1\|1164704_1166321_-\|extracellular-solute-binding-protein	gnl\|CDD\|270299	cd13581, PBP2_AlgQ_like_2, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	0
NZ_CP018838.1\|WP_001113216.1\|1161560_1162832_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP018838.1\|WP_000229332.1\|1174698_1175469_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	4.67193e-17
NZ_CP018838.1\|WP_001844946.1\|1160391_1160598_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	8.85545e-09
NZ_CP018838.1\|WP_000030213.1\|1171812_1172379_+\|alkaline-shock-response-membrane-anchor-protein-AmaP	gnl\|CDD\|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	7.65552e-46
NZ_CP018838.1\|WP_000797961.1\|1166349_1167240_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.20755e-67
NZ_CP018838.1\|WP_000961810.1\|1159902_1160355_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.2282e-11
NZ_CP018838.1\|WP_001809002.1\|1171564_1171729_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	6.92661e-06
NZ_CP018838.1\|WP_001084979.1\|1167250_1168168_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	1.73729e-138
NZ_CP018838.1\|WP_000455066.1\|1172390_1172561_+\|DUF2273-domain-containing-protein	gnl\|CDD\|227834	COG5547, COG5547, Small integral membrane protein [Function unknown].	9.45975e-16

>NZ_CP018838.1|WP_001084979.1|1167250_1168168_-|sugar-ABC-transporter-permease
MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLIAFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAIMLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLTNPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPALKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTAVGLFNAVINVVLLVAVNQIVKRMNNGEGI
>NZ_CP018838.1|WP_000797961.1|1166349_1167240_-|carbohydrate-ABC-transporter-permease
MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDPKVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPLSKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILARAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIVMYPFFQKYFDKGIMAGSLKG
>NZ_CP018838.1|WP_000669745.1|1164704_1166321_-|extracellular-solute-binding-protein
MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQEKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDLPDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHIYSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNGNGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVKFIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAGPSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQQNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLDLIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWDDYKKELEKYGLSDYLAIKQKYYDQYQANKN
>NZ_CP018838.1|WP_000502554.1|1163375_1164695_-|glycoside-hydrolase-family-32-protein
MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNGFVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSGSAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIAADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGREHQGFMWECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDHGQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQFPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTSRRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID
>NZ_CP018838.1|WP_001113216.1|1161560_1162832_+|replication-associated-recombination-protein-A
MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMILYGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHRLDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQIALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITLDIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLARRLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYVAMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKIRNHHYFQAEDTGKYERALAQRKEAIDRLRKI
>NZ_CP018838.1|WP_000818079.1|1161051_1161291_-|hypothetical-protein
MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK
>NZ_CP018838.1|WP_001809903.1|1160707_1160887_-|hypothetical-protein
MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDYTDDELLDKEAVFTTH
>NZ_CP018838.1|WP_001844946.1|1160391_1160598_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MVLSGGKSAIPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELNKYTERGIGKQAGL
>NZ_CP018838.1|WP_000961810.1|1159902_1160355_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAMGSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSVDVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA
>NZ_CP018838.1|WP_000257097.1|1159141_1159612_-|DUF3013-family-protein
MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNAAGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYFALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY
>NZ_CP018838.1|WP_000230204.1|1168317_1169319_-|LacI-family-transcriptional-regulator
MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQAIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCSINGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSDNDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDETVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKMAGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS
>NZ_CP018838.1|WP_001205280.1|1169680_1171162_-|aspartate-aminotransferase
MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSEKYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFMEVDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHLVINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSPYDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE
>NZ_CP018838.1|WP_001809002.1|1171564_1171729_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVITVVSFFTGRK
>NZ_CP018838.1|WP_000030213.1|1171812_1172379_+|alkaline-shock-response-membrane-anchor-protein-AmaP
MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNSVVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFVRSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFGIERQVKLEVAVKNYQPKPQNKKTVSRVK
>NZ_CP018838.1|WP_000455066.1|1172390_1172561_+|DUF2273-domain-containing-protein
MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVAAGLYIEKNYIDK
>NZ_CP018838.1|WP_000064115.1|1172599_1173208_+|Asp23/Gls24-family-envelope-stress-response-protein
MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLENVSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSEIREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQFEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN
>NZ_CP018838.1|WP_000109957.1|1173238_1173442_+|CsbD-family-protein
MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVAEDAKDAVEGAVEGVKNMLSGDDK
>NZ_CP018838.1|WP_001812322.1|1174133_1174421_+|IS30-family-transposase
MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF
>NZ_CP018838.1|WP_000229332.1|1174698_1175469_-|sulfite-exporter-TauE/SafE-family-protein
MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIAFYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVRLVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNVSLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGGVLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL
>NZ_CP018838.1|WP_000782431.1|1175483_1176332_-|formylglycine-generating-enzyme-family-protein
MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPVTNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGTPWWLQVPNACWKHPYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDTLLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRYTLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLGFRCLKE

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Crispr_ID: NZ_CP018838_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018838_2

1628110-1628211

Unclear

Consensus_repeat	Method
GTTGTTTCTTATACAGTTTTTCTTG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP018838_2

>merge|NZ_CP018838|2|1628110-1628211|CRISPRCasFinder
GTTGTTTCTTATACAGTTTTTCTTGCCTACAGCCTCATGCTCTCGGTCGCCAAACTTCTGAGCGTGGGGCTTTTTGAGTTGTTTCTTATACAGTTTTTTCTT

>NZ_CP018838|2|2|1628110-1628211|CRISPRCasFinder
GTTGTTTCTTATACAGTTTTTCTTG	CCTACAGCCTCATGCTCTCGGTCGCCAAACTTCTGAGCGTGGGGCTTTTTGA
GTTGTTTCTTATACAGTTTTTTCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018838.1\|WP_000131181.1\|1630653_1631658_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_001812970.1\|1627538_1627934_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000171245.1\|1627341_1627542_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000122653.1\|1626834_1627128_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000492143.1\|1626244_1626520_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000187312.1\|1620934_1621345_-\|DUF1492-domain-containing-protein	unknown	unknown	gnl\|CDD\|311366
NZ_CP018838.1\|WP_000424667.1\|1628442_1629069_-\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226172
NZ_CP018838.1\|WP_000163932.1\|1634677_1635247_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|223271
NZ_CP018838.1\|WP_001003747.1\|1627124_1627340_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000058847.1\|1626512_1626854_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000158204.1\|1625244_1626105_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214926
NZ_CP018838.1\|WP_000438800.1\|1629158_1629392_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540
NZ_CP018838.1\|WP_001218707.1\|1633491_1634607_+\|redox-regulated-ATPase-YchF	unknown	unknown	gnl\|CDD\|236583
NZ_CP018838.1\|WP_000258140.1\|1635247_1638772_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NZ_CP018838.1\|WP_000704684.1\|1632205_1633372_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP018838.1\|WP_000434362.1\|1623722_1625192_-\|DNA-primase	unknown	unknown	gnl\|CDD\|273716
NZ_CP018838.1\|WP_000417889.1\|1620386_1620779_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_001107586.1\|1629548_1630505_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP018838.1\|WP_000357940.1\|1631657_1632110_+\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	unknown	unknown	gnl\|CDD\|226180
NZ_CP018838.1\|WP_001234978.1\|1638839_1639106_+\|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl\|CDD\|224109

Protein	Function_ID	Function_description	E-value
NZ_CP018838.1\|WP_000438800.1\|1629158_1629392_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	1.78307e-08
NZ_CP018838.1\|WP_000258140.1\|1635247_1638772_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_CP018838.1\|WP_001107586.1\|1629548_1630505_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.10008e-08
NZ_CP018838.1\|WP_000704684.1\|1632205_1633372_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.91623e-44
NZ_CP018838.1\|WP_000163932.1\|1634677_1635247_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|223271	COG0193, Pth, Peptidyl-tRNA hydrolase [Translation, ribosomal structure and biogenesis].	3.56215e-98
NZ_CP018838.1\|WP_000424667.1\|1628442_1629069_-\|Rha-family-transcriptional-regulator	gnl\|CDD\|226172	COG3646, COG3646, Uncharacterized phage-encoded protein [Function unknown].	3.14309e-37
NZ_CP018838.1\|WP_000158204.1\|1625244_1626105_-\|hypothetical-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	2.9188e-17
NZ_CP018838.1\|WP_000357940.1\|1631657_1632110_+\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	gnl\|CDD\|226180	COG3654, Doc, Prophage maintenance system killer protein [General function prediction only].	3.22826e-08
NZ_CP018838.1\|WP_000434362.1\|1623722_1625192_-\|DNA-primase	gnl\|CDD\|273716	TIGR01613, putative_primase, phage/plasmid primase, P4 family, C-terminal domain. This model represents a clade within a larger family of proteins from viruses of bacteria and animals. Members of this family are found in phage and plasmids of bacteria and archaea only. The model describes a domain of about 300 residues, found generally toward the protein C-terminus. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	4.85429e-65
NZ_CP018838.1\|WP_000187312.1\|1620934_1621345_-\|DUF1492-domain-containing-protein	gnl\|CDD\|311366	pfam07374, DUF1492, Protein of unknown function (DUF1492). This family consists of several hypothetical, highly conserved Streptococcal and related phage proteins of around 100 residues in length. The function of this family is unknown. It appears to be distantly related to pfam08281.	1.18881e-07
NZ_CP018838.1\|WP_001218707.1\|1633491_1634607_+\|redox-regulated-ATPase-YchF	gnl\|CDD\|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NZ_CP018838.1\|WP_001234978.1\|1638839_1639106_+\|RNA-binding-S4-domain-containing-protein	gnl\|CDD\|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	4.06015e-32

>NZ_CP018838.1|WP_001812970.1|1627538_1627934_-|hypothetical-protein
MQEIGEKNGLSRLSLLASQTKFIKEELSRLLWIELPELNDSHKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEAEQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ
>NZ_CP018838.1|WP_000171245.1|1627341_1627542_-|hypothetical-protein
MTLDLDNMTQAEFDKQMAEIKERNPNIFQLISDFLDRKVTPEEVDEFLKMERAEQVEYIKNYQARV
>NZ_CP018838.1|WP_001003747.1|1627124_1627340_-|hypothetical-protein
MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTIKTPSEDLNPDYGRYIQLAGVNVWGGME
>NZ_CP018838.1|WP_000122653.1|1626834_1627128_-|hypothetical-protein
MSYTMNLYPDIEKIPDETYFTKEIFLATCLNNTIRIAVARGVLTSQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFVNKSKGEEGLDESIRE
>NZ_CP018838.1|WP_000058847.1|1626512_1626854_-|hypothetical-protein
MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKRLVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESYKETLKEVGGYV
>NZ_CP018838.1|WP_000492143.1|1626244_1626520_-|hypothetical-protein
MFSLSRESEQDLAHGILEVVERYLEAREKVPPRLTKLINRVELKEELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG
>NZ_CP018838.1|WP_000158204.1|1625244_1626105_-|hypothetical-protein
MTIYEARGFQSNLVYPFDKMEPFQYIERFKPLVVPESADPEEYKRTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGYSYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQGLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLFNGFGDEGGRNVAVTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSSIARAEYRKRG
>NZ_CP018838.1|WP_000434362.1|1623722_1625192_-|DNA-primase
MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVTEKVAMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDVRIKPREWPQIKLMVRTLAKIRKPLESANLVPVKNGIIDLRTKELLPFSPKYVITSKISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYGDGNNGKGTFQRFLINLIGESNISALKPAQFGEKHNLETLVGKVCNIGDEAPNEYLKNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNADFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYLLSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTPNRYSLRKKRVPSEDFEKLEAWDVDKIKMRTPQHSITKQE
>NZ_CP018838.1|WP_000187312.1|1620934_1621345_-|DUF1492-domain-containing-protein
MTPEQVKEKLEGVKWINKEIEGLYLELAALESGIIKKQELSNTRVQTSRVNTTENNPISVLKLKEDTLQRIERLNEERMEISRLIDKLANPLERSVLRLFYLNVLDAWQVAEEIDKSKTAVYIIRQKAIEHLANVG
>NZ_CP018838.1|WP_000417889.1|1620386_1620779_-|hypothetical-protein
MELDKFKTMMNVRERMTYFLRFQRMAGSENQVTIDEEAWKLVLPYRWDLSGEHEKAIREGLEIFAQDINSIENKRARKYFIIHYCYMRKKTMSECVEMAATSSTSYHRYKQIAVLNFARIHQNGELEVYK
>NZ_CP018838.1|WP_000424667.1|1628442_1629069_-|Rha-family-transcriptional-regulator
MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESFGKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELSKFRMQRALEKPKRKTLHDSIKTWEAKPKHAHSTMNNLLLKAVTDMNAKQLVKSRGGYNGIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSV
>NZ_CP018838.1|WP_000438800.1|1629158_1629392_-|helix-turn-helix-transcriptional-regulator
MEQWTLKACRVNAGYTLRQVAKKVNKNFQTVSKYEKDSTYIPFELLKELSAIYQVKLDNIFLGDSTKKIELNKRELQ
>NZ_CP018838.1|WP_001107586.1|1629548_1630505_+|helix-turn-helix-transcriptional-regulator
MAKNSPQDLENREYFSKRLNLLMEQKGVRQIDLHNALDIPKSTITGYVKGKSLPTAGNLQKIADFLNVKKSFLDLRFIDTVSTSTLKELLDNNQREKVFEMFFNKIKEILSFKKDYMNMEYIRGKIAFDQGVLGRVLQSSIINPGIVEIFNGLDLSDISKNNEALLLSKQREAREYAYNNVLTMITNEYITRLINVIEREQALNTSYVHSEISNLINSLNNKIDSYGAVVFEVNEIIEKIGIQDRKILGYCLQRKISSVQNEINDLVHNNTNNSFCVTKNKIFTEKSDIIDTIEFDYYKGIQNRLNDLAEEIREHFSD
>NZ_CP018838.1|WP_000131181.1|1630653_1631658_+|hypothetical-protein
MTDLTTSQIERQNILNNSLALQKAEEILKVPGFYFEDTFYFTNSQLATFFEVDIRTIERLVEAHKTELTENGYHTLRGEKLAKFKENAFATDTNVGSKVTQLSISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTALEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNARATMYSEVLIVIASFEKGVAYEIEQKSKSSNQKLTNTDVIEIIQRLANHPMQEPHLMHAREKMASRDLSFRNAKHEKLAEYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
>NZ_CP018838.1|WP_000357940.1|1631657_1632110_+|type-II-toxin-antitoxin-system-death-on-curing-family-toxin
MDKINYFSAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQNDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGIKFLTINHLDYLIPFFIETMENIVLWVAMGLIDFNFLKEIISSILYYEELTEKVKEKLVQIALAEENNK
>NZ_CP018838.1|WP_000704684.1|1632205_1633372_+|site-specific-integrase
MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELKAKALQAQIDFEKGGATVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLLPAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIPFNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATGLRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLYKARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHASILLNAGLPYKEIQIRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS
>NZ_CP018838.1|WP_001218707.1|1633491_1634607_+|redox-regulated-ATPase-YchF
MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMVEVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVHVVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKDKESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVVSEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDKLTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYEDLVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV
>NZ_CP018838.1|WP_000163932.1|1634677_1635247_+|aminoacyl-tRNA-hydrolase
MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIFQADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKIRLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGILQSVDKVDDSVNYYLQEKNFEKTMQRYNG
>NZ_CP018838.1|WP_000258140.1|1635247_1638772_+|transcription-repair-coupling-factor
MVTLLDLLSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASSLEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRVEALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENGYRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKTELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRKFLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDMQYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIERYKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHFVDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGIETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAKQKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEIKRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFKERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMIIDEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGRMSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGRVGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLGKSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQRHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRVERKDNKRKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEILEGLLIFGESLLEIKEFKEENSI
>NZ_CP018838.1|WP_001234978.1|1638839_1639106_+|RNA-binding-S4-domain-containing-protein
MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVNDQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV

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Crispr_ID: NZ_CP018838_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018838_3

1729834-1729929

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018838_3

>merge|NZ_CP018838|3|1729834-1729929|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>NZ_CP018838|3|3|1729834-1729929|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018838.1\|WP_000200890.1\|1734533_1735166_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319798
NZ_CP018838.1\|WP_000198687.1\|1728909_1729503_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
NZ_CP018838.1\|WP_000273864.1\|1729489_1729816_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP018838.1\|WP_020902660.1\|1736979_1737630_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NZ_CP018838.1\|WP_001030032.1\|1724733_1725720_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
NZ_CP018838.1\|WP_100910943.1\|1737681_1738545_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP018838.1\|WP_000838912.1\|1736068_1736740_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NZ_CP018838.1\|WP_001233691.1\|1728005_1728917_-\|DUF4097-domain-containing-protein	unknown	unknown	gnl\|CDD\|372574
NZ_CP018838.1\|WP_001035696.1\|1732377_1734228_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP018838.1\|WP_001108834.1\|1738878_1739466_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_000808471.1\|1726879_1727944_-\|membrane-protein	unknown	unknown	gnl\|CDD\|374284
NZ_CP018838.1\|WP_001075102.1\|1721805_1722729_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP018838.1\|WP_000714582.1\|1720862_1721792_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NZ_CP018838.1\|WP_000500040.1\|1735187_1736060_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP018838.1\|WP_000096188.1\|1731178_1732336_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
NZ_CP018838.1\|WP_000800431.1\|1722986_1724462_+\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
NZ_CP018838.1\|WP_100910944.1\|1739709_1740582_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP018838.1\|WP_000744908.1\|1729954_1731121_-\|CynX/NimT-family-MFS-transporter	unknown	unknown	gnl\|CDD\|225365
NZ_CP018838.1\|WP_153229735.1\|1722802_1722943_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018838.1\|WP_001844757.1\|1725688_1726702_+\|DUF4299-domain-containing-protein	unknown	unknown	gnl\|CDD\|339103

Protein	Function_ID	Function_description	E-value
NZ_CP018838.1\|WP_000200890.1\|1734533_1735166_-\|HAD-family-hydrolase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	8.29103e-98
NZ_CP018838.1\|WP_000198687.1\|1728909_1729503_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	2.84602e-63
NZ_CP018838.1\|WP_000273864.1\|1729489_1729816_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.12912e-19
NZ_CP018838.1\|WP_020902660.1\|1736979_1737630_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	6.24547e-15
NZ_CP018838.1\|WP_001030032.1\|1724733_1725720_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
NZ_CP018838.1\|WP_100910943.1\|1737681_1738545_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.15823e-10
NZ_CP018838.1\|WP_000838912.1\|1736068_1736740_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.1908e-89
NZ_CP018838.1\|WP_001233691.1\|1728005_1728917_-\|DUF4097-domain-containing-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	1.41713e-39
NZ_CP018838.1\|WP_001035696.1\|1732377_1734228_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP018838.1\|WP_000808471.1\|1726879_1727944_-\|membrane-protein	gnl\|CDD\|374284	pfam16001, DUF4775, Domain of unknown function (DUF4775). This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 308 and 484 amino acids in length.	0.000306874
NZ_CP018838.1\|WP_001075102.1\|1721805_1722729_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.04007e-69
NZ_CP018838.1\|WP_000714582.1\|1720862_1721792_+\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	3.01638e-143
NZ_CP018838.1\|WP_000500040.1\|1735187_1736060_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.44295e-105
NZ_CP018838.1\|WP_000096188.1\|1731178_1732336_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	4.05815e-108
NZ_CP018838.1\|WP_000800431.1\|1722986_1724462_+\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.04957e-44
NZ_CP018838.1\|WP_100910944.1\|1739709_1740582_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.58242e-11
NZ_CP018838.1\|WP_000744908.1\|1729954_1731121_-\|CynX/NimT-family-MFS-transporter	gnl\|CDD\|225365	COG2807, CynX, Cyanate permease [Inorganic ion transport and metabolism].	1.76726e-125
NZ_CP018838.1\|WP_001844757.1\|1725688_1726702_+\|DUF4299-domain-containing-protein	gnl\|CDD\|339103	pfam14132, DUF4299, Domain of unknown function (DUF4299). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 275 and 313 amino acids in length. There are two conserved sequence motifs: RGF and DAY. There are two completely conserved residues (P and D) that may be functionally important.	1.9299e-120

>NZ_CP018838.1|WP_000273864.1|1729489_1729816_-|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN
>NZ_CP018838.1|WP_000198687.1|1728909_1729503_-|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEELIASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA
>NZ_CP018838.1|WP_001233691.1|1728005_1728917_-|DUF4097-domain-containing-protein
MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVYDSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDFITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAENIQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR
>NZ_CP018838.1|WP_000808471.1|1726879_1727944_-|membrane-protein
MKQEWFESNDFVKTTSKNKPEEQAQEVSDKAEETIADFDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLTLFSIVSILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>NZ_CP018838.1|WP_001844757.1|1725688_1726702_+|DUF4299-domain-containing-protein
MKAWIKQLLYKIKQSSGAVFLCFVLKNLKFVSVSFRKIRYTVCKRFQRSPVMAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQPLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYTGTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLAQFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLVDKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILDKDFKALAQEE
>NZ_CP018838.1|WP_001030032.1|1724733_1725720_+|rhodanese-related-sulfurtransferase
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
>NZ_CP018838.1|WP_000800431.1|1722986_1724462_+|DUF3502-domain-containing-protein
MKNWKKYAFTSASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK
>NZ_CP018838.1|WP_153229735.1|1722802_1722943_-|hypothetical-protein
MILYSMKIKEQTRKLAAGCSKHCFEVVDKTDEVSYIYLRQGDVDTV
>NZ_CP018838.1|WP_001075102.1|1721805_1722729_+|carbohydrate-ABC-transporter-permease
MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVFVIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE
>NZ_CP018838.1|WP_000714582.1|1720862_1721792_+|sugar-ABC-transporter-permease
MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF
>NZ_CP018838.1|WP_000744908.1|1729954_1731121_-|CynX/NimT-family-MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL
>NZ_CP018838.1|WP_000096188.1|1731178_1732336_+|glycosyltransferase-family-2-protein
MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRPTIIEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML
>NZ_CP018838.1|WP_001035696.1|1732377_1734228_+|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQEIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>NZ_CP018838.1|WP_000200890.1|1734533_1735166_-|HAD-family-hydrolase
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>NZ_CP018838.1|WP_000500040.1|1735187_1736060_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>NZ_CP018838.1|WP_000838912.1|1736068_1736740_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>NZ_CP018838.1|WP_020902660.1|1736979_1737630_+|LysM-peptidoglycan-binding-domain-containing-protein
MKSTTKKIKTTLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHMIYVGQELVIDGPVAPAATPAPTTYAAPAAQDETVSAPAAETTEVAEEAAPVASTPAAEETVATAETSAPAATVSGSEAEAKEWIAQKESGGSYTATNGQYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWSAAKNFWLNNGWY
>NZ_CP018838.1|WP_100910943.1|1737681_1738545_-|helix-turn-helix-transcriptional-regulator
MRYDFGKVYKEIRESKGLTQEEVCGDVLSRTSLSKIESGKVTPKYENMEFLLRQINMSFEEFDYICHIYQPSQRTEIMQTYLNMNSIIGGSGLVHFFETCQNYLKTHHDLPIEEIRDMLEVVIHIRQHGTEQLSDQVKQTVKKLWEKIEKQDTWYESDLKILNTILFSFPIEHLHLITGKILQRLEVYKNYQHLYDLRMAILLNLSTIYLYHQDKNMCQQICYTLLEDAKNKKSYDMLAICYVRIGICRDDAKLIQKGLSLLELTDETSILAYLKKEVEIYYQPKER
>NZ_CP018838.1|WP_001108834.1|1738878_1739466_+|hypothetical-protein
MNYNVKYLLSGIFIIVFIGFLVWMRYFNQKKEEEHSDVSFEARLDSEVKTLYKQLGLGEEPHYFLAYRYLHPWFNLAILPPTVEIFLTKIALVMVTPDELLIRNLGNGMTFTSEHHRDLRQGLIRIPKSEMKEFEIRNWKRVFIFGDFLTIKTSQHSYYLQVRDDGLQKGSLSTKHFSDLKRQDFLGLLTDKRTF
>NZ_CP018838.1|WP_100910944.1|1739709_1740582_+|helix-turn-helix-transcriptional-regulator
MHALLATRLKNKRKELGWSQKELAEGICQQTQISRMEQGKYMPGADLLYKLSEKMGLNMDYFFSGEISKEFLGLSAFKRLSKTLLENQDYASLKYAFEGERKQQTSLSFDEKIYLDWIDAILTYQCEHQLKLVISKIEDILSRISIDKVDYLYILNTLLIFLGYDEDKEKFEQLYDQVSVALSKIDTSVREQIELYIKIKYNYCYHLWKQEEMDKSRALLLEIIEFCNKYHSSFRLADLYCLLGNVTENLDISVAKDYYMKAKVLYLIENNEVMALKVEQYLMDKKSENV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448629	Streptococcus satellite phage Javan742, complete genome	5187-5238	0	1.0
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448646	Streptococcus satellite phage Javan758, complete genome	5186-5237	0	1.0
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448432	Streptococcus satellite phage Javan327, complete genome	4489-4540	1	0.981
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448612	Streptococcus satellite phage Javan725, complete genome	3457-3508	3	0.942
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448495	Streptococcus satellite phage Javan434, complete genome	5542-5593	3	0.942
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448410	Streptococcus satellite phage Javan298, complete genome	3649-3700	3	0.942
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448614	Streptococcus satellite phage Javan727, complete genome	7482-7533	4	0.923
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448623	Streptococcus satellite phage Javan736, complete genome	6059-6110	4	0.923
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448630	Streptococcus satellite phage Javan743, complete genome	7931-7982	4	0.923
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448647	Streptococcus satellite phage Javan759, complete genome	10291-10342	5	0.904
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448643	Streptococcus satellite phage Javan755, complete genome	6646-6697	5	0.904
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448649	Streptococcus satellite phage Javan760, complete genome	4331-4382	5	0.904
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448616	Streptococcus satellite phage Javan729, complete genome	8547-8598	5	0.904
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448627	Streptococcus satellite phage Javan740, complete genome	7031-7082	5	0.904
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	KT337367	Streptococcus phage phiARI0826b, partial genome	32391-32442	7	0.865
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	KT337369	Streptococcus phage phiARI0831b, partial genome	29445-29496	7	0.865
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	FR671407	Streptococcus phage 34117	36073-36124	7	0.865
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	NC_024361	Streptococcus phage DCC1738, complete sequence	36829-36880	7	0.865
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	NC_024357	Streptococcus phage K13, complete sequence	37797-37848	7	0.865
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448640	Streptococcus satellite phage Javan752, complete genome	3884-3935	7	0.865
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448634	Streptococcus satellite phage Javan747, complete genome	2570-2621	7	0.865
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448986	Streptococcus phage Javan570, complete genome	1517-1568	8	0.846
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448455	Streptococcus satellite phage Javan364, complete genome	3323-3374	8	0.846
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448445	Streptococcus satellite phage Javan344, complete genome	5150-5201	9	0.827
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448555	Streptococcus satellite phage Javan592, complete genome	3565-3616	11	0.788
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448547	Streptococcus satellite phage Javan572, complete genome	3566-3617	11	0.788
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448535	Streptococcus satellite phage Javan550, complete genome	3566-3617	11	0.788
NZ_CP018838_2	2.1\|1628135\|52\|NZ_CP018838\|CRISPRCasFinder	1628135-1628186	52	MK448544	Streptococcus satellite phage Javan564, complete genome	2943-2994	11	0.788

1. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448629 (Streptococcus satellite phage Javan742, complete genome) position: , mismatch: 0, identity: 1.0

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
****************************************************

2. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448646 (Streptococcus satellite phage Javan758, complete genome) position: , mismatch: 0, identity: 1.0

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
****************************************************

3. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448432 (Streptococcus satellite phage Javan327, complete genome) position: , mismatch: 1, identity: 0.981

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcacgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
************.***************************************

4. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448612 (Streptococcus satellite phage Javan725, complete genome) position: , mismatch: 3, identity: 0.942

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tctacagcctcatgctctcggtcgccaaatttctgaacgtggggctttttga	Protospacer
.****************************.******.***************

5. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448495 (Streptococcus satellite phage Javan434, complete genome) position: , mismatch: 3, identity: 0.942

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaatttctgagcatggggctttttaa	Protospacer
*****************************.********.***********.*

6. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448410 (Streptococcus satellite phage Javan298, complete genome) position: , mismatch: 3, identity: 0.942

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
cctacagcctcatgctctcggtcgccaaatttctgagcatggggctttttaa	Protospacer
*****************************.********.***********.*

7. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448614 (Streptococcus satellite phage Javan727, complete genome) position: , mismatch: 4, identity: 0.923

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcacgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
 ..*** ******.***************************************

8. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448623 (Streptococcus satellite phage Javan736, complete genome) position: , mismatch: 4, identity: 0.923

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaacttctgagcgtgggtctttttga	Protospacer
 ..*** ************************************* ********

9. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448630 (Streptococcus satellite phage Javan743, complete genome) position: , mismatch: 4, identity: 0.923

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcacgctctcggtcgccaaacttctgagcgtggggctttttga	Protospacer
 ..*** ******.***************************************

10. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448647 (Streptococcus satellite phage Javan759, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
 ..*** ******************************************** .

11. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448643 (Streptococcus satellite phage Javan755, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
 ..*** ***********************.************* ********

12. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448649 (Streptococcus satellite phage Javan760, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-ccacatgcctcacgctctcggtcgccaaacttctgagcgtggggctttttac	Protospacer
 *.*** ******.*************************************.

13. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448616 (Streptococcus satellite phage Javan729, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
 ..*** ***********************.************* ********

14. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448627 (Streptococcus satellite phage Javan740, complete genome) position: , mismatch: 5, identity: 0.904

cctaca-gcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
-tcacatgcctcacgctctcggtcgccaaacttctgagcgtgggtctttttga	Protospacer
 ..*** ******.****************************** ********

15. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to KT337367 (Streptococcus phage phiARI0826b, partial genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtactagcctcatgctctcggtcgccaaacttctgagcgtggggcttttttt	Protospacer
 .  .*********************************************

16. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to KT337369 (Streptococcus phage phiARI0831b, partial genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtactagcctcatgctctcggtcgccaaacttctgagcgtggggcttttttt	Protospacer
 .  .*********************************************

17. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to FR671407 (Streptococcus phage 34117) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
ctcctagcctcacgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
*.. .*******.************************************* .

18. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to NC_024361 (Streptococcus phage DCC1738, complete sequence) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
ctcctagcctcacgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
*.. .*******.************************************* .

19. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to NC_024357 (Streptococcus phage K13, complete sequence) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
ctcctagcctcacgctctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
*.. .*******.************************************* .

20. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448640 (Streptococcus satellite phage Javan752, complete genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tcgcatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
.*    ***********************.************* ********

21. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448634 (Streptococcus satellite phage Javan747, complete genome) position: , mismatch: 7, identity: 0.865

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tcgcatgcctcatgctctcggtcgccaaatttctgagcgtgggtctttttga	Protospacer
.*    ***********************.************* ********

22. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448986 (Streptococcus phage Javan570, complete genome) position: , mismatch: 8, identity: 0.846

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tagcttgcctcacgctctcggtcgccaaacttctgagcgtggggctttttta	Protospacer
.   . ******.************************************* *

23. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448455 (Streptococcus satellite phage Javan364, complete genome) position: , mismatch: 8, identity: 0.846

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
tgaagttcctcacgctctcggtcgccaaatttctgagcgtggggctttttga	Protospacer
.  *   *****.****************.**********************

24. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448445 (Streptococcus satellite phage Javan344, complete genome) position: , mismatch: 9, identity: 0.827

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
aggatatcctcacactctcggtcgccaaacttctgagcgtggggcttttttg	Protospacer
   *.* *****..************************************ .

25. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448555 (Streptococcus satellite phage Javan592, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

26. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448547 (Streptococcus satellite phage Javan572, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

27. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448535 (Streptococcus satellite phage Javan550, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

28. spacer 2.1|1628135|52|NZ_CP018838|CRISPRCasFinder matches to MK448544 (Streptococcus satellite phage Javan564, complete genome) position: , mismatch: 11, identity: 0.788

cctacagcctcatgctctcggtcgccaaacttctgagcgtggggctttttga	CRISPR spacer
gtaattgcctcatgctctcggtcgcctaatttctgagcgtggggctttggtt	Protospacer
 . *. ******************** **.******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8839 : 47398

Streptococcus_phage(25.0%)

tRNA,bacteriocin,protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000530080.1\|8839_10096_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.0e-233	96.9
WP_001808898.1\|10304_10424_-	hypothetical protein	NA	NA	NA	NA
WP_000410533.1\|10388_10538_+	hypothetical protein	NA	NA	NA	NA
WP_061760599.1\|11234_12272_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000651177.1\|12328_13126_+	tyrosine-type DNA invertase PsrA	A0A0H4TI16	Erysipelothrix_phage	1.3e-21	28.7
WP_001813510.1\|13136_13742_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000029046.1\|15259_16723_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_000229097.1\|16735_19069_-	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	2.0e-25	26.5
WP_001242576.1\|19438_19639_+	hypothetical protein	NA	NA	NA	NA
WP_001088694.1\|19673_20183_+	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_000255770.1\|20346_21381_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_000046031.1\|21407_21932_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_000034662.1\|22420_24244_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.3e-133	47.2
WP_000114433.1\|24245_24602_+	hypothetical protein	NA	NA	NA	NA
WP_001810236.1\|25003_26140_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	3.1e-24	31.3
WP_000777760.1\|26874_27162_-	hypothetical protein	NA	NA	NA	NA
WP_001278300.1\|27171_27582_-	HIT family protein	B5LJ12	Mycobacterium_phage	3.4e-05	31.6
WP_000889925.1\|27649_28381_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.3e-25	28.6
WP_000653767.1\|28377_29427_+	multidrug ABC transporter permease	NA	NA	NA	NA
WP_000132572.1\|29594_29924_-	hypothetical protein	NA	NA	NA	NA
WP_000682135.1\|30200_30539_+	response regulator transcription factor	NA	NA	NA	NA
WP_001219120.1\|30543_31281_+	response regulator transcription factor	NA	NA	NA	NA
WP_001017638.1\|31294_32635_+	sensor histidine kinase	NA	NA	NA	NA
WP_000358817.1\|32676_32832_-	quorum-sensing system pheromone BlpC	NA	NA	NA	NA
WP_001069091.1\|32888_34250_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_001093259.1\|36699_36897_+\|bacteriocin	bacteriocin-like peptide BlpI	NA	NA	NA	NA
WP_001093248.1\|37363_37633_+\|bacteriocin	bacteriocin-like peptide BlpJ	NA	NA	NA	NA
WP_000379964.1\|37701_37932_+\|bacteriocin	bacteriocin-like peptide BlpU	NA	NA	NA	NA
WP_000346298.1\|37934_38054_+	hypothetical protein	NA	NA	NA	NA
WP_000727118.1\|38350_38515_+	hypothetical protein	NA	NA	NA	NA
WP_000846944.1\|38511_38916_+	hypothetical protein	NA	NA	NA	NA
WP_000379879.1\|40067_40322_+\|bacteriocin	two-peptide bacteriocin subunit BlpM	NA	NA	NA	NA
WP_001099492.1\|40337_40541_+\|bacteriocin	two-peptide bacteriocin subunit BlpN	NA	NA	NA	NA
WP_001809846.1\|40784_40934_+\|bacteriocin	bacteriocin-like peptide BlpO	NA	NA	NA	NA
WP_000346296.1\|41037_41157_+	hypothetical protein	NA	NA	NA	NA
WP_078139298.1\|41927_42362_+	immunity protein	NA	NA	NA	NA
WP_000760521.1\|42376_43066_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000276498.1\|43107_43341_+	hypothetical protein	NA	NA	NA	NA
WP_001838554.1\|43671_45018_+\|transposase	IS1380-like element ISSpn5 family transposase	A0A1X9I6F6	Streptococcus_phage	2.6e-78	40.2
WP_000638370.1\|45199_45811_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000363002.1\|45971_46766_+	phosphotransferase family protein	NA	NA	NA	NA
WP_001266083.1\|46762_47398_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA

DBSCAN-SWA_2

349064 : 410117

Streptococcus_phage(52.38%)

protease,transposase,integrase,tRNA,bacteriocin

attL 352674:352714|attR 405735:405775

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001200062.1\|349064_350279_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_001076703.1\|350413_351238_+	esterase family protein	NA	NA	NA	NA
WP_001108634.1\|351250_352417_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
352674:352714	attL	NA	NA	NA	NA
WP_100910876.1\|352924_354418_+	SAM-dependent DNA methyltransferase	A0A2H4UVB0	Bodo_saltans_virus	1.5e-26	31.5
WP_001826876.1\|354430_354973_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000756129.1\|354969_356025_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000260605.1\|356084_356321_+	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_000158366.1\|356317_356731_+	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_000444456.1\|356848_357814_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	1.8e-33	29.6
WP_061378071.1\|357779_358355_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000526341.1\|358384_361735_+	DEAD/DEAH box helicase family protein	A0A2H4P9W3	Gordonia_phage	2.4e-11	24.8
WP_054386074.1\|362240_362711_-	arginine repressor	NA	NA	NA	NA
WP_001212037.1\|362727_365001_-	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
WP_010963257.1\|365320_368449_+	DNA polymerase III subunit alpha	A0A291AWR1	Streptomyces_phage	9.0e-114	32.8
WP_000820852.1\|368530_369538_+	ATP-dependent 6-phosphofructokinase	NA	NA	NA	NA
WP_001042809.1\|369596_371102_+	pyruvate kinase	NA	NA	NA	NA
WP_001167984.1\|371376_371625_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5S8R9	Streptococcus_phage	1.7e-12	52.1
WP_000536835.1\|372174_372429_-	phage repressor protein	B3GVX0	Streptococcus_phage	3.3e-19	61.2
WP_000749605.1\|372864_373737_+	DUF4300 family protein	NA	NA	NA	NA
WP_000420566.1\|374369_374681_+	hypothetical protein	NA	NA	NA	NA
WP_000759775.1\|374684_375401_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_100910877.1\|375523_376780_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.8e-233	96.9
WP_000617843.1\|376952_377768_-	TIGR03943 family protein	NA	NA	NA	NA
WP_000123614.1\|377764_378670_-	permease	NA	NA	NA	NA
WP_000268689.1\|378670_378802_-	hypothetical protein	NA	NA	NA	NA
WP_000359149.1\|379126_381256_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_000778587.1\|381242_381692_+	SprT family protein	NA	NA	NA	NA
WP_001844074.1\|381720_382023_+	PspC domain-containing protein	NA	NA	NA	NA
WP_000680767.1\|382376_382568_-	hypothetical protein	NA	NA	NA	NA
WP_000173358.1\|382995_383754_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-27	36.3
WP_000489386.1\|383755_385744_+	ABC transporter permease	NA	NA	NA	NA
WP_001153880.1\|386454_387450_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	1.5e-35	35.4
WP_074186901.1\|387682_387865_-	hypothetical protein	NA	NA	NA	NA
WP_000661000.1\|388156_389632_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000366713.1\|390567_391428_+	polyamine aminopropyltransferase	NA	NA	NA	NA
WP_000088783.1\|391424_392684_+	saccharopine dehydrogenase family protein	NA	NA	NA	NA
WP_000764369.1\|392683_393811_+	carboxynorspermidine decarboxylase	NA	NA	NA	NA
WP_000969445.1\|393807_394893_+	agmatine deiminase	M1HES8	Acanthocystis_turfacea_Chlorella_virus	1.6e-89	47.5
WP_001246753.1\|394902_395778_+	N-carbamoylputrescine amidase	M1H5W0	Paramecium_bursaria_Chlorella_virus	1.9e-77	50.0
WP_000593568.1\|395958_396768_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000602449.1\|397039_397261_+\|bacteriocin	SP_0924 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000745380.1\|397314_397986_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001025709.1\|398227_399136_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	3.1e-06	27.7
WP_000745389.1\|399132_399594_+	signal peptidase II	NA	NA	NA	NA
WP_000403193.1\|399583_400471_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000728291.1\|400473_402357_+	MBL fold metallo-hydrolase	Q332B9	Clostridium_botulinum_C_phage	9.5e-10	22.9
WP_075218898.1\|402436_403567_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-114	58.4
WP_000254687.1\|403576_404839_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-140	64.8
WP_000689700.1\|404842_405640_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.1e-60	50.9
WP_000033389.1\|405861_406500_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.7e-75	68.1
405735:405775	attR	NA	NA	NA	NA
WP_000806716.1\|406496_407387_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.4e-72	51.4
WP_000358228.1\|407426_407744_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
WP_001166872.1\|407746_408616_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	75.7
WP_001261452.1\|408842_409361_+	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
WP_000345254.1\|409469_410117_+	replication initiator protein A	A0A2P0VK56	Streptococcus_phage	7.0e-13	33.7

DBSCAN-SWA_3

630599 : 640195

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050197910.1\|630599_633068_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	4.6e-105	35.5
WP_000204727.1\|633261_634248_+	L-lactate dehydrogenase	NA	NA	NA	NA
WP_000731137.1\|634584_635280_-	potassium channel family protein	A0A1B0Y2S3	Lactobacillus_phage	5.4e-19	44.0
WP_001061866.1\|635326_635590_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000134770.1\|635582_635885_-	hypothetical protein	NA	NA	NA	NA
WP_000530078.1\|636018_637275_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	6.6e-233	96.7
WP_001289493.1\|637337_638147_-	MBL fold metallo-hydrolase	A0A0C5AFC1	Paenibacillus_phage	1.8e-34	39.0
WP_100910888.1\|638148_639498_-	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	5.2e-34	34.0
WP_000722076.1\|639490_640195_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.8e-39	39.8

DBSCAN-SWA_4

718897 : 747710

Streptococcus_phage(88.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000420682.1\|718897_719212_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|719227_719614_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|719642_721028_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|721030_721183_+	hypothetical protein	NA	NA	NA	NA
WP_001815707.1\|721205_722624_+	helix-turn-helix domain-containing protein	A0A1S5SEX3	Streptococcus_phage	1.5e-233	100.0
WP_001860874.1\|722672_722756_+	23S rRNA methyltransferase attenuator leader peptide ErmL	NA	NA	NA	NA
WP_001038795.1\|722880_723618_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.1e-134	99.2
WP_000085862.1\|723622_723754_+	hypothetical protein	E4ZFP9	Streptococcus_phage	7.9e-17	100.0
WP_000019067.1\|723874_725122_-\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	3.9e-12	23.9
WP_001009056.1\|725301_725523_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|725639_726137_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|726111_726618_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|726601_729049_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_100910889.1\|729051_731229_+	hypothetical protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	99.9
WP_000769868.1\|731225_732227_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_100910890.1\|732223_733111_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.4e-157	93.9
WP_012386611.1\|733385_733472_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691744.1\|733487_735407_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.3
WP_011058338.1\|735507_735693_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
WP_001814874.1\|736306_736390_+	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_001038790.1\|736514_737252_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_000085855.1\|737256_737388_+	hypothetical protein	E4ZFP9	Streptococcus_phage	8.2e-14	90.7
WP_000576156.1\|737606_738161_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
WP_001240982.1\|738164_741083_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
WP_013670292.1\|741582_741654_+	hypothetical protein	NA	NA	NA	NA
WP_000804885.1\|741882_742305_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|742301_742532_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_001845478.1\|742757_743009_-	hypothetical protein	NA	NA	NA	NA
WP_000814511.1\|742992_743196_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|743277_744495_+\|transposase	transposase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000821309.1\|744709_745297_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000840776.1\|745299_745533_-	hypothetical protein	NA	NA	NA	NA
WP_000566524.1\|745545_745926_-	hypothetical protein	NA	NA	NA	NA
WP_000645887.1\|745918_746368_-	hypothetical protein	NA	NA	NA	NA
WP_001210966.1\|746351_747710_-	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	3.9e-130	56.3

DBSCAN-SWA_5

832294 : 873787

Streptococcus_phage(23.08%)

tRNA,holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000245766.1\|832294_832744_-\|transposase	transposase	NA	NA	NA	NA
WP_075218957.1\|833038_833407_-\|transposase	transposase	NA	NA	NA	NA
WP_000691853.1\|833330_833525_-\|transposase	transposase	NA	NA	NA	NA
WP_001812990.1\|833721_834045_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_001136122.1\|834025_834211_-	hypothetical protein	NA	NA	NA	NA
WP_100910896.1\|834514_836077_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.9e-19	32.8
WP_100910897.1\|836217_836916_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000071672.1\|836958_837855_-	EamA family transporter	NA	NA	NA	NA
WP_000872215.1\|837863_838799_-	serine hydrolase	NA	NA	NA	NA
WP_001102211.1\|838795_839521_-	proteinase	NA	NA	NA	NA
WP_000290657.1\|839604_840240_-\|holin	1-alkyl-2-acetylglycerophosphocholine esterase	A0A2K9L661	Tupanvirus	8.7e-08	28.7
WP_000972931.1\|840241_841069_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000526284.1\|841090_841426_-	hypothetical protein	NA	NA	NA	NA
WP_001272961.1\|842667_843279_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
WP_000855753.1\|843323_844052_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000272294.1\|844090_845002_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	5.9e-90	51.5
WP_001206968.1\|845067_845304_-	DUF4059 family protein	NA	NA	NA	NA
WP_000590970.1\|845369_846113_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-29	40.5
WP_001103449.1\|846112_846913_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000889093.1\|847070_847427_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
WP_001170346.1\|847439_847952_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.3e-46	55.6
WP_000405832.1\|847951_848446_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.9e-42	52.1
WP_000858730.1\|848580_849027_+	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_001097993.1\|849023_849671_+	hemolysin III family protein	NA	NA	NA	NA
WP_000689945.1\|849691_850273_-	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA	NA	NA	NA
WP_000138517.1\|850273_851149_-	pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA	NA	NA	NA
WP_000036789.1\|851300_852680_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_000175407.1\|852973_853897_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_000915944.1\|853956_854562_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	5.9e-54	54.2
WP_000673678.1\|854579_855824_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	3.8e-55	52.7
WP_000371287.1\|855919_856177_-	DUF896 family protein	NA	NA	NA	NA
WP_000164771.1\|856218_858255_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_000038736.1\|858466_859384_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_000369583.1\|859751_860513_-	hypothetical protein	NA	NA	NA	NA
WP_001099675.1\|860785_861628_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.7e-51	40.2
WP_001852192.1\|861741_863133_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_001810003.1\|863367_863745_-	hypothetical protein	NA	NA	NA	NA
WP_078139260.1\|863911_864973_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_000850564.1\|864969_866052_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.4e-36	31.0
WP_001040724.1\|867534_868731_-	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	7.3e-32	29.6
WP_000348122.1\|869652_870522_-	aquaporin family protein	NA	NA	NA	NA
WP_000248996.1\|870744_871266_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_001810000.1\|871237_872329_-	MucBP domain-containing protein	NA	NA	NA	NA
WP_000935663.1\|872439_872694_-	hypothetical protein	NA	NA	NA	NA
WP_000284543.1\|872687_872930_-	hypothetical protein	NA	NA	NA	NA
WP_000200307.1\|873051_873585_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_001809998.1\|873571_873787_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

911946 : 985487

Streptococcus_phage(86.15%)

terminase,head,protease,integrase,tRNA,portal,tail,holin

attL 919441:919473|attR 992522:992554

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000390783.1\|911946_912696_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_000689596.1\|912749_913109_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_000339025.1\|913110_914511_-	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	2.0e-25	44.6
WP_000068664.1\|914805_915045_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_000609600.1\|915076_915547_-	single-stranded DNA-binding protein	A0A286QQM5	Streptococcus_phage	9.2e-55	71.2
WP_001151785.1\|915558_915849_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_000167151.1\|916001_917345_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	6.3e-56	31.2
WP_000565218.1\|917363_917729_-	VOC family protein	NA	NA	NA	NA
WP_000777773.1\|917721_918909_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000153791.1\|918905_919337_-	hypothetical protein	NA	NA	NA	NA
919441:919473	attL	NA	NA	NA	NA
WP_000039617.1\|919714_920263_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_000697785.1\|920540_921269_-	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	2.0e-40	39.0
WP_001856244.1\|921347_921527_-	YczI family protein	NA	NA	NA	NA
WP_000822873.1\|921678_923274_-	hypothetical protein	NA	NA	NA	NA
WP_000412218.1\|923285_923696_-	peptide deformylase	A0A2I7R224	Vibrio_phage	1.3e-09	33.1
WP_001277411.1\|923811_924603_-	glutathione-dependent disulfide-bond oxidoreductase	NA	NA	NA	NA
WP_000032467.1\|924615_927312_-	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	3.1e-70	28.5
WP_000813916.1\|927615_928800_+	CDF family manganese efflux transporter MntE	NA	NA	NA	NA
WP_001279153.1\|928942_930814_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.1e-55	31.1
WP_001858603.1\|930810_932010_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	6.9e-38	32.6
WP_000027897.1\|932006_932774_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_000762061.1\|933039_933888_-	DegV family protein	NA	NA	NA	NA
WP_001808399.1\|933889_934276_-	DUF1149 family protein	NA	NA	NA	NA
WP_000521418.1\|934337_935690_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_000742290.1\|935713_936493_-	YbbR-like domain-containing protein	NA	NA	NA	NA
WP_001011058.1\|936479_937337_-	TIGR00159 family protein	NA	NA	NA	NA
WP_000081003.1\|937471_938440_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	2.8e-66	100.0
WP_000350525.1\|938692_939649_-	N-acetylmuramoyl-L-alanine amidase family protein	A0A1S5SBM2	Streptococcus_phage	1.5e-144	99.4
WP_001186239.1\|939648_939984_-\|holin	phage holin	A0A126GGL9	Streptococcus_phage	3.4e-51	99.1
WP_001810279.1\|939987_940287_-	hypothetical protein	A0A1S5SC89	Streptococcus_phage	1.4e-45	100.0
WP_000852249.1\|940296_940647_-	hypothetical protein	A0A060QMT7	Streptococcus_phage	4.7e-64	100.0
WP_001091119.1\|940649_940853_-	hypothetical protein	X2KU40	Streptococcus_phage	1.1e-25	100.0
WP_000068023.1\|947394_947745_-	hypothetical protein	A0A141E0R8	Streptococcus_phage	9.8e-62	99.1
WP_000212166.1\|947753_951347_-	hypothetical protein	A0A141E0R9	Streptococcus_phage	0.0e+00	98.6
WP_000478007.1\|951333_951684_-	hypothetical protein	A0A060QN56	Streptococcus_phage	2.1e-56	100.0
WP_001185631.1\|951722_952103_-	hypothetical protein	A0A1S5SF40	Streptococcus_phage	9.3e-66	100.0
WP_000880665.1\|952107_952521_-\|tail	tail protein	A0A1S5SF61	Streptococcus_phage	3.3e-72	99.3
WP_000608235.1\|952523_952892_-	hypothetical protein	A0A1S5SFB8	Streptococcus_phage	1.2e-65	100.0
WP_000015940.1\|952888_953404_-	HK97 gp10 family phage protein	A0A141E0I0	Streptococcus_phage	9.3e-93	100.0
WP_001812940.1\|953378_953681_-	hypothetical protein	X2KU30	Streptococcus_phage	2.0e-42	100.0
WP_000021218.1\|953697_954009_-	hypothetical protein	A0A1S5S8S7	Streptococcus_phage	7.2e-48	99.0
WP_000669348.1\|954010_954199_-	hypothetical protein	A0A141DZN7	Streptococcus_phage	1.4e-27	100.0
WP_000863393.1\|954208_955234_-	sugar-binding protein	A0A1S5S8Q2	Streptococcus_phage	7.3e-190	99.7
WP_001288018.1\|955256_955781_-	DUF4355 domain-containing protein	E8ZDV2	Streptococcus_phage	1.7e-73	98.9
WP_000565273.1\|956262_956676_-	HD domain-containing protein	A0A1S5SBR9	Streptococcus_phage	5.4e-67	100.0
WP_000651746.1\|956672_956882_-	hypothetical protein	A0A1S5SB88	Streptococcus_phage	3.3e-33	100.0
WP_000356287.1\|956883_958467_-\|head	head morphogenesis protein	A0A1S5SDJ1	Streptococcus_phage	5.1e-299	99.2
WP_000285392.1\|958429_959899_-\|portal	phage portal protein	A0A1S5SBD1	Streptococcus_phage	1.5e-276	99.2
WP_000084412.1\|959910_961209_-\|terminase	PBSX family phage terminase large subunit	A0A141E1F1	Streptococcus_phage	7.2e-259	99.3
WP_000863690.1\|961186_961699_-\|terminase	terminase small subunit	A0A060QNR7	Streptococcus_phage	1.5e-87	99.4
WP_001030244.1\|962968_963391_-	DUF1492 domain-containing protein	A0A141E1Y4	Streptococcus_phage	6.3e-71	100.0
WP_001268499.1\|963508_963826_-	hypothetical protein	A0A1S5SDY8	Streptococcus_phage	1.4e-51	98.1
WP_001041163.1\|963887_964415_-	DUF1642 domain-containing protein	A0A1S5SE80	Streptococcus_phage	2.4e-96	96.0
WP_000391853.1\|964416_964731_-	hypothetical protein	A0A1S5SDB3	Streptococcus_phage	1.5e-56	98.1
WP_000119453.1\|964881_965220_-	hypothetical protein	A0A1S5SDI1	Streptococcus_phage	5.6e-62	100.0
WP_000580029.1\|965664_967008_-	hypothetical protein	A0A1S5SAS5	Streptococcus_phage	7.7e-256	99.3
WP_000097191.1\|967010_967832_-	hypothetical protein	A0A1S5SDK7	Streptococcus_phage	6.5e-157	99.3
WP_000054337.1\|968004_968508_-	hypothetical protein	A0A126GGP3	Streptococcus_phage	2.9e-91	98.8
WP_000885998.1\|968527_969304_-	AAA family ATPase	A0A141DZQ7	Streptococcus_phage	8.7e-143	100.0
WP_001044592.1\|969303_969621_-	hypothetical protein	X2KPG0	Streptococcus_phage	2.0e-53	100.0
WP_100910900.1\|969639_970833_-	type III restriction endonuclease subunit R	X2KU10	Streptococcus_phage	5.3e-232	99.7
WP_000696057.1\|970795_971281_-	hypothetical protein	X2KUD4	Streptococcus_phage	1.4e-87	98.8
WP_000422308.1\|971280_971640_-	hypothetical protein	A0A1S5SB89	Streptococcus_phage	2.3e-58	99.2
WP_000157805.1\|971639_972122_-	siphovirus Gp157 family protein	A0A1S5S7W2	Streptococcus_phage	1.4e-79	100.0
WP_000544342.1\|972114_972837_-	HNH endonuclease	A0A141E0V1	Streptococcus_phage	3.3e-136	98.8
WP_000252078.1\|972850_973081_-	hypothetical protein	X2KU06	Streptococcus_phage	2.2e-33	100.0
WP_000189400.1\|973081_973423_-	hypothetical protein	A0A1S5S7X8	Streptococcus_phage	1.4e-57	100.0
WP_000970850.1\|973434_973626_-	hypothetical protein	A0A1S5SDN5	Streptococcus_phage	2.3e-28	100.0
WP_001050924.1\|973622_973817_-	hypothetical protein	X2KSX0	Streptococcus_phage	1.8e-09	100.0
WP_000454230.1\|973813_974086_-	hypothetical protein	A0A1S5SDW9	Streptococcus_phage	8.8e-42	100.0
WP_000834564.1\|974426_974618_+	hypothetical protein	X2KSW6	Streptococcus_phage	1.5e-27	98.4
WP_001826935.1\|974571_974778_-	hypothetical protein	A0A141E1R6	Streptococcus_phage	4.0e-31	100.0
WP_001112859.1\|974800_974992_-	DNA-binding protein	A0A141DZR9	Streptococcus_phage	3.0e-28	100.0
WP_000142893.1\|975056_975296_+	hypothetical protein	A0A141DZS0	Streptococcus_phage	4.7e-39	100.0
WP_001810072.1\|975519_975609_+	hypothetical protein	NA	NA	NA	NA
WP_000970295.1\|975831_975924_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_000493111.1\|976321_976675_+	helix-turn-helix transcriptional regulator	A0A1S5SEQ8	Streptococcus_phage	7.1e-60	99.1
WP_000156313.1\|976676_977771_+	hypothetical protein	A0A1S5SFA1	Streptococcus_phage	3.5e-206	100.0
WP_000151192.1\|977993_978374_+	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	1.1e-66	99.2
WP_000266847.1\|978515_979643_+\|integrase	site-specific integrase	A0A1S5SEM0	Streptococcus_phage	4.5e-209	100.0
WP_000011306.1\|979730_980642_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.5e-154	99.7
WP_001231086.1\|980638_981616_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
WP_000163035.1\|981612_982503_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	6.7e-06	29.8
WP_001140412.1\|982554_982935_-	RidA family protein	NA	NA	NA	NA
WP_000422599.1\|982945_983533_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_024478652.1\|983541_984774_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-131	59.0
WP_000442260.1\|984810_984981_-	hypothetical protein	NA	NA	NA	NA
WP_000162467.1\|984980_985487_-	dihydrofolate reductase	A0A1B2IBQ4	Erwinia_phage	3.0e-19	37.4
992522:992554	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1237699 : 1245031

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000167830.1\|1237699_1238401_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.2e-34	36.5
WP_077141275.1\|1238808_1239783_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	5.4e-57	40.5
WP_001193668.1\|1239772_1240729_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_000764303.1\|1240725_1241478_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.6e-14	28.1
WP_000858263.1\|1241573_1242539_+	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000821640.1\|1242763_1243006_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.3e-17	59.4
WP_100910914.1\|1243005_1243728_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000105310.1\|1243714_1244284_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
WP_000351907.1\|1244302_1245031_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	5.3e-09	22.3

DBSCAN-SWA_8

1593503 : 1602256

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000510412.1\|1593503_1594343_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	1.1e-15	32.6
WP_000835713.1\|1594327_1595155_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	2.1e-22	32.9
WP_000712132.1\|1595151_1595697_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_001844398.1\|1595707_1596538_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000170191.1\|1596570_1597854_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	8.4e-18	30.0
WP_000424269.1\|1597850_1599101_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	8.6e-92	42.1
WP_000455898.1\|1599259_1599628_+	hypothetical protein	A0A1X9I5V8	Streptococcus_phage	4.5e-17	56.0
WP_100910936.1\|1599630_1600728_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_100910937.1\|1600777_1602256_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	4.9e-94	40.5

DBSCAN-SWA_9

1625244 : 1633372

Streptococcus_phage(71.43%)

integrase

attL 1619776:1619790|attR 1633438:1633452

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1619776:1619790	attL	NA	NA	NA	NA
WP_000158204.1\|1625244_1626105_-	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	6.5e-123	74.5
WP_000492143.1\|1626244_1626520_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	5.6e-20	56.8
WP_000058847.1\|1626512_1626854_-	hypothetical protein	NA	NA	NA	NA
WP_000122653.1\|1626834_1627128_-	hypothetical protein	NA	NA	NA	NA
WP_001003747.1\|1627124_1627340_-	hypothetical protein	NA	NA	NA	NA
WP_000171245.1\|1627341_1627542_-	hypothetical protein	NA	NA	NA	NA
WP_001812970.1\|1627538_1627934_-	hypothetical protein	NA	NA	NA	NA
WP_000424667.1\|1628442_1629069_-	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	6.1e-30	40.8
WP_000438800.1\|1629158_1629392_-	helix-turn-helix transcriptional regulator	X2KUC2	Streptococcus_phage	6.4e-09	43.9
WP_001107586.1\|1629548_1630505_+	helix-turn-helix transcriptional regulator	A0A060QNS7	Streptococcus_phage	5.5e-14	41.0
WP_000131181.1\|1630653_1631658_+	hypothetical protein	A0A0S2SXZ1	Bacillus_phage	1.2e-11	29.1
WP_000357940.1\|1631657_1632110_+	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_000704684.1\|1632205_1633372_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	5.9e-103	51.5
1633438:1633452	attR	NA	NA	NA	NA

DBSCAN-SWA_10

1675547 : 1687003

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000668299.1\|1675547_1677701_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	4.2e-46	28.2
WP_000801603.1\|1677713_1679063_+	HlyD family secretion protein	NA	NA	NA	NA
WP_001843991.1\|1679190_1679940_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	1.4e-41	39.2
WP_050167432.1\|1679941_1680085_+	hypothetical protein	NA	NA	NA	NA
WP_000361164.1\|1680141_1683867_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.6e-37	25.6
WP_000220632.1\|1683959_1685402_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.7e-55	35.1
WP_000182575.1\|1685438_1686461_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	1.2e-64	43.9
WP_000717506.1\|1686457_1687003_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.4e-24	35.0

DBSCAN-SWA_11

1741090 : 1773005

Planktothrix_phage(33.33%)

tRNA,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100910945.1\|1741090_1741375_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_100910946.1\|1741429_1743538_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000571330.1\|1743534_1744176_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.3e-23	34.8
WP_001038484.1\|1744382_1745189_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_001810177.1\|1745205_1746402_+	argininosuccinate synthase	NA	NA	NA	NA
WP_001268171.1\|1747538_1748402_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001818085.1\|1748867_1751087_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	5.2e-39	25.9
WP_001096141.1\|1751079_1751547_+	hypothetical protein	NA	NA	NA	NA
WP_000781019.1\|1751543_1752896_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_000420335.1\|1753043_1753349_+\|bacteriocin	SPAR17_0115 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000424408.1\|1753682_1754036_+	hypothetical protein	NA	NA	NA	NA
WP_078158541.1\|1754002_1754761_+	hypothetical protein	NA	NA	NA	NA
WP_000989850.1\|1754914_1755127_+	hypothetical protein	NA	NA	NA	NA
WP_000513492.1\|1755605_1755851_+	hypothetical protein	NA	NA	NA	NA
WP_001810284.1\|1756007_1757066_+	hypothetical protein	NA	NA	NA	NA
WP_001810285.1\|1757380_1758358_+	hypothetical protein	NA	NA	NA	NA
WP_000424473.1\|1758734_1759109_+\|bacteriocin	SPH_0224 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000511666.1\|1759115_1759298_+	hypothetical protein	NA	NA	NA	NA
WP_000619777.1\|1759316_1760219_+	hypothetical protein	NA	NA	NA	NA
WP_078135349.1\|1760241_1760628_+	argininosuccinate lyase	NA	NA	NA	NA
WP_000539710.1\|1760594_1761353_+	hypothetical protein	NA	NA	NA	NA
WP_000680086.1\|1761831_1762029_+	hypothetical protein	NA	NA	NA	NA
WP_078102794.1\|1762425_1762725_+	hypothetical protein	NA	NA	NA	NA
WP_001810010.1\|1762709_1762988_+	hypothetical protein	M1Q0Z8	Streptococcus_phage	1.1e-20	50.5
WP_001035351.1\|1763273_1765514_+	hypothetical protein	NA	NA	NA	NA
WP_001282967.1\|1765914_1767036_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_078140550.1\|1767149_1767632_+	NUDIX hydrolase	NA	NA	NA	NA
WP_000220946.1\|1767641_1769555_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_000331980.1\|1769933_1771613_-	ribonuclease J	NA	NA	NA	NA
WP_000639577.1\|1771614_1771848_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_001844323.1\|1772474_1772672_-	hypothetical protein	NA	NA	NA	NA
WP_000977347.1\|1772665_1772818_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibB	NA	NA	NA	NA
WP_000180803.1\|1772819_1773005_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibA	NA	NA	NA	NA

DBSCAN-SWA_12

1864232 : 1933498

Streptococcus_phage(33.33%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000900660.1\|1864232_1865492_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_000814073.1\|1865504_1867358_+\|tRNA	proline--tRNA ligase	A0A2K9L297	Tupanvirus	9.7e-07	26.8
WP_000943506.1\|1867456_1868836_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_000334247.1\|1869027_1870836_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	1.2e-99	38.7
WP_000229754.1\|1870955_1872005_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_000530078.1\|1872183_1873440_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	6.6e-233	96.7
WP_001232833.1\|1873527_1877370_-	LPXTG-anchored pullulanase SpuA	NA	NA	NA	NA
WP_001808847.1\|1877707_1877800_+	hypothetical protein	NA	NA	NA	NA
WP_001142332.1\|1877786_1878200_+	30S ribosomal protein S12	NA	NA	NA	NA
WP_000087873.1\|1878219_1878690_+	30S ribosomal protein S7	NA	NA	NA	NA
WP_000090347.1\|1879114_1881196_+	elongation factor G	E4ZFJ7	Streptococcus_phage	1.7e-63	29.0
WP_000530078.1\|1881288_1882545_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	6.6e-233	96.7
WP_000071430.1\|1882722_1887114_+	PolC-type DNA polymerase III	A0A0K2SUJ2	Clostridium_phage	2.1e-20	38.5
WP_000041497.1\|1887215_1887479_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_000913054.1\|1887471_1887750_+	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_000776632.1\|1887770_1887923_+	hypothetical protein	NA	NA	NA	NA
WP_000243919.1\|1887944_1889186_+	aminopeptidase	NA	NA	NA	NA
WP_000901567.1\|1889195_1889426_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_001234893.1\|1889648_1890371_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000991674.1\|1890482_1891817_+	aminopeptidase C	NA	NA	NA	NA
WP_000136861.1\|1891872_1892784_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_000022715.1\|1892807_1893611_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_000021975.1\|1893638_1894628_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_000649163.1\|1894861_1895881_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	7.9e-27	25.6
WP_000162352.1\|1896219_1897032_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000359279.1\|1897221_1898640_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	5.8e-44	31.2
WP_061823262.1\|1898744_1899452_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_078158432.1\|1899576_1900527_+	dihydropteroate synthase	NA	NA	NA	NA
WP_000658398.1\|1900528_1901851_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000380924.1\|1901831_1902386_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	3.7e-39	43.8
WP_000372532.1\|1902428_1903265_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_000530081.1\|1903271_1904528_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.5e-234	97.1
WP_000886031.1\|1904812_1905130_-	DUF960 domain-containing protein	NA	NA	NA	NA
WP_001044624.1\|1905486_1905933_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_000075973.1\|1905951_1906344_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_100910976.1\|1906690_1906834_-	hypothetical protein	NA	NA	NA	NA
WP_078139270.1\|1908287_1909538_+	glycoside hydrolase family 31 protein	NA	NA	NA	NA
WP_000203063.1\|1909759_1910236_-	glutathione peroxidase	NA	NA	NA	NA
WP_075271548.1\|1910425_1913662_+	LPXTG-anchored hyaluronate lyase	NA	NA	NA	NA
WP_000167295.1\|1914805_1915435_-	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_000161480.1\|1915444_1916446_-	sugar kinase	NA	NA	NA	NA
WP_000684786.1\|1916476_1917118_-	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_000185874.1\|1917136_1917952_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_000706826.1\|1918223_1918658_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_000592943.1\|1918669_1919860_+	unsaturated chondroitin disaccharide hydrolase	NA	NA	NA	NA
WP_000178622.1\|1919870_1920362_+	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_000026610.1\|1920376_1921156_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_000148012.1\|1921142_1921961_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_000381739.1\|1921960_1922254_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_000657078.1\|1922275_1924177_+	alginate lyase family protein	NA	NA	NA	NA
WP_001844476.1\|1924170_1925238_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000838117.1\|1925347_1925683_-	hypothetical protein	NA	NA	NA	NA
WP_000711739.1\|1925693_1925936_-	hypothetical protein	NA	NA	NA	NA
WP_001082474.1\|1925951_1926146_-	helix-turn-helix transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	7.2e-06	42.6
WP_000159418.1\|1926311_1927262_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_000818547.1\|1927273_1927591_+	cell division protein FtsL	NA	NA	NA	NA
WP_100910957.1\|1927594_1929847_+	PASTA domain-containing protein	NA	NA	NA	NA
WP_100910958.1\|1929848_1930829_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_054376650.1\|1931392_1933498_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.0e-116	37.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018838

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection