CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP025096	Spirosoma pollinicola strain Ha7 chromosome, complete genome	15 crisprs	csa3,WYL,PD-DExK,cas5,cas8b4,cas7b,cas3,cas4,cas1,cas2,Cas9_archaeal,DEDDh,cas7,cas6,RT	0	16	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP025096_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_1

1045999-1046101

Orphan

Consensus_repeat	Method
TCCTGGGGTATTGGGTCATGTGGTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025096_1

>merge|NZ_CP025096|1|1045999-1046101|CRISPRCasFinder
TCCTGGGGTATTGGGTCATGTGGTGTCCTGGGTCATGTGGTGTCCTGGGTCATGTGGTGTCCTGGGTCATGTGGATGTCCTGGGGTATTGGGTCATGTGGTGT

>NZ_CP025096|1|1|1045999-1046101|CRISPRCasFinder
TCCTGGGGTATTGGGTCATGTGGTGT	CCTGGGTCATGTGGTGTCCTGGGTCATGTGGTGTCCTGGGTCATGTGGATG
TCCTGGGGTATTGGGTCATGTGGTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100986650.1\|1055382_1056066_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP025096.1\|WP_100993731.1\|1048577_1048895_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
NZ_CP025096.1\|WP_100986637.1\|1048030_1048486_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100986615.1\|1032628_1033207_-\|thioredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|372611
NZ_CP025096.1\|WP_100986627.1\|1042006_1042519_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP025096.1\|WP_100986646.1\|1051513_1053853_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NZ_CP025096.1\|WP_100986641.1\|1050650_1050869_+\|cysteine-rich-CWC-family-protein	unknown	unknown	gnl\|CDD\|379586
NZ_CP025096.1\|WP_100986623.1\|1039199_1041467_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|226434
NZ_CP025096.1\|WP_100986648.1\|1053968_1055180_+\|exo-alpha-sialidase	unknown	unknown	gnl\|CDD\|271234
NZ_CP025096.1\|WP_100993732.1\|1050145_1050670_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|237426
NZ_CP025096.1\|WP_100986619.1\|1034113_1036504_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|226434
NZ_CP025096.1\|WP_100986631.1\|1044785_1045295_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP025096.1\|WP_100986617.1\|1033265_1033739_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100986625.1\|1041546_1041954_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379154
NZ_CP025096.1\|WP_100986643.1\|1051004_1051382_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_170069403.1\|1046146_1047970_-\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350096
NZ_CP025096.1\|WP_100986621.1\|1036593_1039128_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|226434
NZ_CP025096.1\|WP_100986639.1\|1048961_1049891_-\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_CP025096.1\|WP_100986629.1\|1043509_1044730_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340888
NZ_CP025096.1\|WP_100986633.1\|1045374_1045821_-\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993731.1\|1048577_1048895_+\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	3.9289e-18
NZ_CP025096.1\|WP_100986650.1\|1055382_1056066_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.09388e-80
NZ_CP025096.1\|WP_100986615.1\|1032628_1033207_-\|thioredoxin-domain-containing-protein	gnl\|CDD\|372611	pfam13462, Thioredoxin_4, Thioredoxin.	4.79387e-23
NZ_CP025096.1\|WP_100986627.1\|1042006_1042519_+\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	6.00941e-36
NZ_CP025096.1\|WP_100986646.1\|1051513_1053853_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	9.55202e-43
NZ_CP025096.1\|WP_100986641.1\|1050650_1050869_+\|cysteine-rich-CWC-family-protein	gnl\|CDD\|379586	pfam14375, Cys_rich_CWC, Cysteine-rich CWC. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 74 and 102 amino acids in length. It contains eight conserved cysteines, including a conserved CWC sequence motif.	3.55691e-05
NZ_CP025096.1\|WP_100986623.1\|1039199_1041467_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|226434	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms].	1.07999e-57
NZ_CP025096.1\|WP_100986648.1\|1053968_1055180_+\|exo-alpha-sialidase	gnl\|CDD\|271234	cd15482, Sialidase_non-viral, Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.	8.85989e-07
NZ_CP025096.1\|WP_100993732.1\|1050145_1050670_+\|PAS-domain-containing-protein	gnl\|CDD\|237426	PRK13558, PRK13558, bacterio-opsin activator; Provisional.	3.31613e-23
NZ_CP025096.1\|WP_100986619.1\|1034113_1036504_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|226434	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms].	2.13347e-50
NZ_CP025096.1\|WP_100986631.1\|1044785_1045295_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.000210298
NZ_CP025096.1\|WP_100986625.1\|1041546_1041954_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379154	pfam13384, HTH_23, Homeodomain-like domain.	6.37219e-09
NZ_CP025096.1\|WP_170069403.1\|1046146_1047970_-\|family-43-glycosylhydrolase	gnl\|CDD\|350096	cd08982, GH43-like, Glycosyl hydrolase family 43 protein; uncharacterized. This glycosyl hydrolase family 43 (GH43)-like subfamily includes uncharacterized enzymes similar to those with beta-1,4-xylosidase (xylan 1,4-beta-xylosidase; EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanase and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	1.12932e-155
NZ_CP025096.1\|WP_100986621.1\|1036593_1039128_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|226434	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms].	3.16439e-53
NZ_CP025096.1\|WP_100986639.1\|1048961_1049891_-\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.1646e-83
NZ_CP025096.1\|WP_100986629.1\|1043509_1044730_-\|MFS-transporter	gnl\|CDD\|340888	cd17330, MFS_SLC46_TetA_like, Eukaryotic Solute carrier 46 (SLC46) family, Bacterial Tetracycline resistance proteins, and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of the eukaryotic proteins MFSD9, MFSD10, MFSD14, and SLC46 family proteins, as well as bacterial multidrug resistance (MDR) transporters such as tetracycline resistance protein TetA and multidrug resistance protein MdtG. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. TetA proteins confer resistance to tetracycline while MdtG confers resistance to fosfomycin and deoxycholate. The Solute carrier 46 (SLC46) family is composed of three vertebrate members (SLC46A1, SLC46A2, and SLC46A3), the best-studied of which is SLC46A1, which functions both as an intestinal proton-coupled high-affinity folate transporter involved in the absorption of folates and as an intestinal heme transporter which mediates heme uptake. MFSD10 facilitates the uptake of organic anions such as some non-steroidal anti-inflammatory drugs (NSAIDs) and confers resistance to such NSAIDs. The SLC46/TetA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.60529e-25
NZ_CP025096.1\|WP_100986633.1\|1045374_1045821_-\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.56046e-25

>NZ_CP025096.1|WP_100986633.1|1045374_1045821_-|IS200/IS605-family-transposase
MSYRQILYHIVFGTKRRNPTIDDAYCSELYQYIWGVIKNKNCKLFRINGVEDHIHILSDLHPSVALADFVKDIKVASSLWMKSSGLFPEFEGWAEGYGAFTYSVKERDRVINYIKKQKEHHQKVTFNDEYKSLLDEHEITYDEKYLFI
>NZ_CP025096.1|WP_100986631.1|1044785_1045295_-|GNAT-family-N-acetyltransferase
MQFTFRNDQPDTALTLLREVGQWLVDNDRGLWNVDTLTPENLIDEYTKDNLFVMYADRGDGTDPEPAAVFILQWEDPLYWPDVEANTSGFIHKLAIRRLFSGQNLFAAIIDFSREECLKRGIKTLQLETDATRPKLMQFYERYGFQPTYQRDMQEFGQSFTCQFYVMTF
>NZ_CP025096.1|WP_100986629.1|1043509_1044730_-|MFS-transporter
MPTHRPARDYRLYQIYAIIFIDVIVGSAVGPILPEFVKGLDRPQLWLAVGTALFLGMQLFSAPLLGKLSDGYGRRPIFIISAIGTFLADCLLLPVRVGYYFANRISDGTTNGMYATVRSAITDISPKENLFKNLGIEGAIVSLGFVIGPAASGLLLTTFDVVQGDQARVVAIMAVSLSSLNMILSWTLRETHPNPPGVEPAALKMELAQSLDVHTLWRRLLAKDNQYKGLKKLVLMQLALTLGLGYYFYFVTFVSFGALQLDARGISYFFMYFGALSVVISYVFYAYIADRINQRRGIFWLALLGVPILGGYGLVGTSMLWLYILVTIDCLTFSLIQGLIEGLMAQLTTDEDRGEIFGINQALQGVASFITTVVFGCLSLLDLRLPFGWFAACLAVVAWLAWERQP
>NZ_CP025096.1|WP_100986627.1|1042006_1042519_+|IS630-family-transposase
MYADKYERWKLLLTLWLLGYIELYFGDESGFTMQPYVPYAWQKKGLTQRRFARRQNNRLNVFGLMSLSGQLTVYHSEANLDGAFIKNCLDDFARKVHPKPYVIVLDNGPIHHAKVVKTEFDTWESQGLSIFYLPTYSPHLNPIEILWRFCKYKWLNKTHYKSWSTLKLAS
>NZ_CP025096.1|WP_100986625.1|1041546_1041954_+|helix-turn-helix-domain-containing-protein
MSRKEKHIDLNESEQITLREGAKYHPKPEFREKCRALLLNQTGVTIKQIATHLDVNHNTVGTWINTWETAGIVGLNRKLGQGRNPILSVTNPRHIGHLDKAVDTHAQNVKAIQAELVKELNTPMSSDTVKRFLKK
>NZ_CP025096.1|WP_100986623.1|1039199_1041467_+|tetratricopeptide-repeat-protein
MINRMQLISLSVWCLFTLQVQAQLSAPQLDSVRNQLKGSLNDTTRVKLLLELGTFKLDLATQTKTNQDSTVLLFQQALTLSNQLGQQKWKDESLYQLGTYYLRNNKLAKGKAYFTRVIKAYQQAGNKAQESRAWFRMGTGILRIGENYAEILSAFGHALALANQLGDRQQEATIRSAMGDMHSIMGEFNEAEKEYLRVLTIQKAIGDKRIYKTYFSLSNIGFYRGDFNSALSYALKMIKAVETSGNTGELDYAYFRLGNVYFELGQIDKSVEAYRKSLAISKQKGQVIVDVALAKKLSRALLKQGRAQEALHFLTTIDRKNLPLIIDDKMTMAESFGECYAALKQYKRAEAYYLESIAWSKKTASWVALVANMGIGRFYVATSQYAKASPYLQKLLSAPQGQVPANILMEVHLMQFKVDSAAGRYVVAIAQFQQYKALNDSIFNAGKSRQINELEIQYETEKKEQQIQLLTEKEQRQQSELKRAQTTRYGFIAGAILLAGLLGMSYNRYRLKQRSHQLLEAQQQEINLKNDSLRQILTEKDQLLEEKEWMLKEIHHRVKNNLQIISSLLHSQSVFLTDPTAQSAIRESQNRVHAMALIHQKLYQSDRLANVDLSEYIEEIVDYLITSFDRQDTILKQIAVSPVGLDITLAVPLGLLINEAVTNSLKHAFPSEQAGFIAVELTKPDRKTYRLTIRDNGIGLPVDVNPDQSQTLGMSLIRGLSKQLKGTLQIDQNDGVQISLLFMTEQVDHETFINS
>NZ_CP025096.1|WP_100986621.1|1036593_1039128_+|tetratricopeptide-repeat-protein
MKLIAKSDNRQSSKGLPEVVLSDRAMHWLLFKYLCNCFVGFYPTPTPPLEIRGGAQAYHFFSPSPYFKGRGWGGVNYRNTYGDFLKRLVPCFGLLAGLVLTGLSSWGQNINRQMVNQYLTQLASNPNDTSRINALIALGKFHVLKYGEVKPDLDSAKGYLNQAKALSTKLHLTSKRHAAETMLVVAHMELRDTTVGNLLFTELINDCKRTNDRNGQADALSRFGACSVFTTKNFPVVLACYAQAASLYHSLGNYEAEIYILREIAAFHTNQGKLDVGNNEFINVLNRYKAIQYPKLHYTYSWLSYINRLKGNYGKALGYSFLCLESMNRTQDTLLAATFYGDVAQIYWELGKQQQAISWYKKALQKWRQEKHADLPMYNVASIIARDMTAHYKAPEAINLLNTLVREIPPINKVQKGCIAQSLANSYKALHQPELAERYYLEAIDWYEKSHQNTEMSQKVQAEVGQFYLEQQDSRKAGLFLEKSLAFIPQKHALSTVKDIHYMLFKVDSAQGKYLSAIHHFRLHKTLNDSLFNETKAKQIAQLEIQYETKENKHNISLLRKESNLQATELKQARTIRNTILICSILLLCLLGLSYNRYRLKQKSNQLLETKQREINQKNQALETLLSAQQQLLTEKEWMLKEIHHRVKNNLQIITSLLHSQGVFLTDQAAQSAIRESQNRVHAMALIHQKLYQSDQLTAIPMAGYVTEIVDYLIQSFDREDTVRKQISLAPIDLDVTLAVPLGLIINEIVTNSLKHAFPFNQSGIIGVDLIKLDSQTYQLTVSDNGIGLPADINPNHSQTLGMSLIWGLSKQLGGRLQINHDDGVQISLTFTEEKIVKEMVGRD
>NZ_CP025096.1|WP_100986619.1|1034113_1036504_+|tetratricopeptide-repeat-protein
MTASVYFFPFVQARIKPIGSGRSIQFIRSSILRWSCPFIWVNVCLLFSLLTSHLSAQGQNINRQMANQLLAQLPKSQADTGRVRILFELGKYQLFKPGNVPADLERSLSYLNQAKHLSDSLHLLTWQHEIDAVRVANYLEGANSKAAYALFDQLIADCRRTGDRASEANARFRLGFCISFTTKKYPEIFDNYNQAIAIYRSLHNQKQELLILHEIAGLHTSLGQLDLAQKEFLTILKRYKAIGYPKLHYTYNWLSTISRLKGDFNKSLFYSLQCIESMNRTGDTVSAASFYGNLAQMYFELGRYRQSNDWYRKTLAKWRQEGLPNYGMYSAANIIVRDLIEQHKPQEALKLINDLVTQIPTINFIQKGSVAQSFAYSYDALKNDKLAEKYYLEAMRWYIEANHDFEMSRKAQLEVGRFYVERNQFKKGNFYVRPLLVDSTKKNSLSLLKDIHFMLFKIDSAVGDYKSAIAHFRIHKALNDSIFNETKNNQFDQLEVQYETQKNRQNIVLLEKQKTLQDGELKQARLVRNGILGGSVLLLCLLALSYNRYRLKRRSNQLLETKQHEINRKNQTLETLLSEQQQLLTEKEWMLKEIHHRVKNNLQIITSLLHSQGVFLKDEAAQSAIRESQNRVHAMALIHQKLYQSDRLAAIPMTGYVAEIIDYLIKSFDREGTIRKKINVIPLELDVTLAVPLGLILNEAVTNSLKYAFIAGNPGLICVELTAQENHYLLVVSDNGRGFPADFNPQMSQTLGMSLMHGLSKQIGGSLQIGSSDDKGVEVRLEFSDEVVGKESINAL
>NZ_CP025096.1|WP_100986617.1|1033265_1033739_-|hypothetical-protein
MKRFIIFFRWLVGPSMTTLIEELHVRLLNDWILTQDPAFIHPQCTWKLADGHVCSGTHLGRDFFRNYQRQLDRTYPDWYEVVSEVIGSSIGGIIIGTYQFQRETNGLWYSAPFTHFYRIQRGQIVSAYYYMGEVSTHLDRFQSTTYFPTYAAFPSLN
>NZ_CP025096.1|WP_100986615.1|1032628_1033207_-|thioredoxin-domain-containing-protein
MNSIATNFPADMGGPAPTIELTEFGDFTCGQCRRSRSLLSSVVSAFDGRVRYTYRHFPNERSDASRMAALAAEAARRQEQFWPMYQALFTLPTITRTTLSMLAISLGLQYHQFLTDLDDEDLHHRIEADRRDGHQLGVMTTPALFVDGHRFYGKMTLSRLAPLIQSHLSRHAQPVLSKVDVARGMIYWGRGE
>NZ_CP025096.1|WP_170069403.1|1046146_1047970_-|family-43-glycosylhydrolase
MRFLILLFLTICSLENIAQVQKKTYCNPMDISYRYNFEQLNEKISYRSGADPVIINHKKEYYLFVTIQGGWWHSKDLINWNYIVPDKWPMEDMCAPAALSVRDTMYLFQSTFEQRPIFYSTEPEKGKLKFLNRWMPRLPKDIGPWDPALFHDDDTDKWYMYWGSSNVYPLFGAELDKKRNLTYAGNNPAEAYKAMLWLDPYKHGWERFGPNHSDPFKPFTEGAWMTKYKGKYYLQYGAPGTEYNVYGNGTYVSKDPLGPFEYAPYNPVAYKPGGFATGCGHGNTFQDNFGNYWNTGTTWIGYNWGMERRIVMNPAGFDKDDQLFANTRFGDFPHYLATKAVPSQNGMETDELFTGWMLLSYRKPAVASSTLKASPTDTLSADRTTDEDPRTFWVANQNKPGETLTLDLGAERDVRAVQVDYIDYKQTVYDSDSTVYTQFKILTSTDNKKWTVAADLTKEPKRDRACAYVELDPRGDGKPVRARYVRYEHVYVAGSHLAINAFRVFGNGQGKVPATPATLTAKRQKDQRNADLSWSKVPGAVGYNIRWGIAPDKLYQNYQFWNDQPNTFELRALNVGVPYYFAIEAFDENGVSVLSKVVDDGSGLGKK
>NZ_CP025096.1|WP_100986637.1|1048030_1048486_+|hypothetical-protein
MTNINKTILQSLGSGLAGACALTALHETARQFISDAPRADILGMRAIKKVMEVADEEPPADDELHDWALGGDIVSNALYYSLIGLAKPKDALVTGAALGLAAGVGAVGLPGPMGLGTAPSSRTTATAAMTIGWYLLGGLVTAGAYTWLKRK
>NZ_CP025096.1|WP_100993731.1|1048577_1048895_+|antibiotic-biosynthesis-monooxygenase
MIATTPTPPYYAVIFTSIRTDYNDGYSDMATRMVEMAHLQPGFLGVESARTELGITVSYWESPESIRVWKEKAEHLIAQQIGRERWYESYKIRVCKVERDYGFEL
>NZ_CP025096.1|WP_100986639.1|1048961_1049891_-|cation-transporter
MAHEHNHEEHAGHHHGPTVLTSVNRALIIGAILNTVYVIVEFGMGFYYHSLALAADAGHNLSDVASLLLSLLAFRLARVRQTPGFTYGYRKSTVLASLTNAVILLITIGAILWESISRFRHPEPVAGGAVAWVAGLGILVNAASAMLFFRNKEHDLNAKGAYLHLVVDALVSLGVVVAGVLITYTGWTWLDPLIGILVAIIIMGSTWRLLTDSLRLSMDGIPADIDLPDVLADLRAVAGVQDVHHVHVWAMSTTENALTAHLVLAPNLSVAAVNKLKADARHRLEHRKISHATLETEIGAGDDCGSEVC
>NZ_CP025096.1|WP_100993732.1|1050145_1050670_+|PAS-domain-containing-protein
MNFCGPYDKKLAEQYQPVLHTPIAAGWEFRQKPLLLAGSAGWRSLAKLQDWALTASVRHELLSDKWTIVITDQHQIIQYVNPHFEKMTGYSNYEAIGRRPSFLQSEETSKLSRLRIRQAIEQQKSVSELMLNFRKDQTPYWCQVTIRPISNRQKEVVNYIAFEQEVPFDESSLS
>NZ_CP025096.1|WP_100986641.1|1050650_1050869_+|cysteine-rich-CWC-family-protein
MNPALVNKHQNVDCPRCQRPFTCRAGTISVCQCSTLVLTDAQHRYINFLYQGCLCANCLFDLQSEYTQKTGS
>NZ_CP025096.1|WP_100986643.1|1051004_1051382_+|hypothetical-protein
MKGALVYILLIATLLPTVSPWGTIAYYHVNKDYIARVLCENRDKPQLHCDGKCYLAKQLKAQQDRQDKETTERVQNTPLLQLFCQANLPFQFRSVLTVLASVEFSAYTFPSYVAPMSGPFHPPQV
>NZ_CP025096.1|WP_100986646.1|1051513_1053853_+|TonB-dependent-receptor
MNMYKLFIALGLWTMTACVALAQSATKGLVFDAQTKEPIPGVTLVFPDGKGTITDANGQFVLTANSTKVIISAVGYRKQEVTLIPNQSVRVALEPAVEDLQTVVVTGNREAALRTETPIAISKLSAKLINETKPTSIFEVINKTPGVLMVNLNNEQHMMAIRQPMTTNAYFLYMEDGVPIRPMGVFNHNALLEMNQFTVSSIEVVKGPVSSIYGPEAVGGAVNFITQRPTAVPTARVGIQFDQWGYKRLQFGAGARQGKFGIYLGGFVSKQRNSWMASSNYDKSSYFTRLEYAFTPKTRLTGTLSYNDYTSQTSGSVDSTAFFSRQYASTTDFTYRKTFSFRSRLTLEHDWKDGSASFVTAFVRNNSVGQNPAYSIRWVSGAATATGQINSNDFKSYGVIAQHTQKLNFLNSKLIVGTTLDLSPNSYYAYQTDLTTELRADKKSVIKYTQVKERPDIQLANYQADIHNVATYVQYDFDPLPKLRVSAGVRYDRMAFDYTNALDKSSGDKAYSQATPKIGATYDLSNGKGIYLNYAKGFSPPALTAIFLKRTNPTVTGDLFYYNLQPARFTNMEIGGWASLLNNKIYVDAALYQMNGTNELLNIRQPDNSTDYQSAGQTLHRGVEFSLTYRPSKQVFFRFGGTHAVHQFVEFTLSQKVSDVVQNVNGKDMPSAPRTFWNTEISYYPVWLKNFRSSVEWQHVGAWYQNQTNTIKYGGYDFANVRVGYQWKGIELFSNILNATNVLFATNATRGNNATDRTTYTPAAPRTFVFGVQYSFSGK
>NZ_CP025096.1|WP_100986648.1|1053968_1055180_+|exo-alpha-sialidase
MKSLLITLLLFCLMAAKSVNETPVSNPQFVGGVPRFTTDATGSPLLSWVEKISEKEAAFYFAISSDGQTFGEKIRVKAPPNISVHAEGMPKVAVKADGTLLAVFEVPNPTPESRFAGDLLYTMSTDNGKSWTEPVPVHQNVKPGTSHSFSDITRLPNGEIGVVFLDEKLPGREGRPVVFAQTIKGKGFGTAVLVDDNACQCCRTNVFVDAKENIHLTYRDLLPSGKTDVPASRDISTAVSTDGGKTFGKPQVVFADHWQVNACPHAGPVVAQLGNDILMTWFSGKEDAVGLRLARLGSDKLASSVLSNRAKHPQIATAGNQLVWVWDEAVSKDGSNQMGSFVQRIGMCTFAGGESSSTTYLTPETVDATYPAVLATKQGVLVAYEQTKDKGKPVIVVRQLAAQ
>NZ_CP025096.1|WP_100986650.1|1055382_1056066_+|response-regulator-transcription-factor
MRVLIVEDEWEVASLIKAGLEEYDFVPDIAGNAMEAQKQLADHEYEAIILDVNLPVISGFDLCRMIRNRFDTLPILILTAFGSTDSKVNGFDAGADDYLVKPFEFRELVARLRALNRRSGAMAQEAVVLKIADLELNQQSKTVKRDNQKLILTARELALLEFFLKNQNRALTRNEITEHVWDINFDTGTNLVDVYVNYLRKKIDKDFSPKLIHTISGIGYIMQAGDE

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Crispr_ID: NZ_CP025096_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_2

2327801-2332861

Unclear

Consensus_repeat	Method
GTCTCAATCGCACCTTCGGGTATTGAAAG	PILER-CR
GTCTCAATCGCACCTTCGGGTATTGAAAG	CRISPRCasFinder
GTCTCAATCGCACCTTCGGGTATTGAAAG	CRT

77 spacers

cas2,cas1,cas4,cas3,cas7b,cas8b4,cas5,WYL,PD-DExK

The CRISPR arrays of NZ_CP025096_2

>merge|NZ_CP025096|2|2327801-2332861|PILER-CR,CRISPRCasFinder,CRT
GTCTCAATCGCACCTTCGGGTATTGAAAGGTACTTGGGTCGAGTTCACCACTCAGTACAACATCCGGTCTCAATCGCACCTTCGGGTATTGAAAGCAAGACGCGCTGAGCAATGGCCGCGCTGGTTGCTGAGTCTCAATCGCACCTTCGGGTATTGAAAGGATAACTGCTTCGGCAACTTTCTGACCCAGATAGTGTCTCAATCGCACCTTCGGGTATTGAAAGCATCCGAATCTGGATCGGGCAAGGGTGAAGCGGGTCTCAATCGCACCTTCGGGTATTGAAAGCCATCGGGATTCGTTGTGGCAAACGTGCTGGCTGGAGTCTCAATCGCACCTTCGGGTATTGAAAGTTGTACTGGCGGGCAAACGCTGCCCATTTTTGGCCGGTCTCAATCGCACCTTCGGGTATTGAAAGGCGCTTAATATCTCGGTACAAATTGAATTGAATCGAGTCTCAATCGCACCTTCGGGTATTGAAAGCTATTAATACCGGCTGTGCCCCCTTCTCTCCCAGGTCTCAATCGCACCTTCGGGTATTGAAAGTGGGTTTTTCTTCGCCTCCAACCGGGAAGTGTCGAGTCTCAATCGCACCTTCGGGTATTGAAAGGTATGTAGGTATTGGTAACGTAGTTGAAGTTGTTGCGTCTCAATCGCACCTTCGGGTATTGAAAGTCCTATGGTAGTTGATGATCGCTTTGTAATAGCGAAGTCTCAATCGCACCTTCGGGTATTGAAAGTTATTCAAACGCGACTCGGTCGGCAAGGCCAGCGGTGGTCTCAATCGCACCTTCGGGTATTGAAAGTCCGGTGCCTGCGTGGTCGTATAGTCACTTCTGGCCCGTCTCAATCGCACCTTCGGGTATTGAAAGGCGTTTGAGGGTGAACTATCGGGCAGACTGCCAGCTGGTCTCAATCGCACCTTCGGGTATTGAAAGGCAAAAACAGGTGCATGTGCCCATTGGGGCCATTAAGTCTCAATCGCACCTTCGGGTATTGAAAGCTACGCATCGCTGGCAGGCATGGCGGGCGTTTTCCTGTCTCAATCGCACCTTCGGGTATTGAAAGGCGATAAGGCCCCCGATGAGGTTGCCCATACCCTCGGTCTCAATCGCACCTTCGGGTATTGAAAGACGAAAGCGTAACCCGGCTGTATCTGGATACCAAGGGTCTCAATCGCACCTTCGGGTATTGAAAGGCAATGAGGGCTTTACCAATGGCGGCATAATAATTGGGTCTCAATCGCACCTTCGGGTATTGAAAGGCAATGAGGGCTTTACCAATGGCGGCATAATAATTGGGTCTCAATCGCACCTTCGGGTATTGAAAGCAGCGGATTGAATTGCGCTGGCGGTATCGGTCTTTGTCTCAATCGCACCTTCGGGTATTGAAAGTTATTGAGGGGAAGGTTGGTTACAGGCAACTGGAAAAAGTCTCAATCGCACCTTCGGGTATTGAAAGGTATTTTAAAAATGCCGGAATCAAAAAAGGTTGTGGTCTCAATCGCACCTTCGGGTATTGAAAGCTGGCTGTATCGCCTATAGCCGTGACTTCACAGACGAGTCTCAATCGCACCTTCGGGTATTGAAAGCTGGAAAGAAAAAAGCGCCGGATAGTTTTATTGAGCGTCTCAATCGCACCTTCGGGTATTGAAAGTTGAGAATGATTGTATCGTCAATAAAATGTCCGACATAACGTCTCAATCGCACCTTCGGGTATTGAAAGGGTTAAGCCATGACCGCTACGGAGTGACTTATCATTCAGTCTCAATCGCACCTTCGGGTATTGAAAGTGTAGGTGGTAAAGCCCGTCAGTACCACATTGGAAAGTCTCAATCGCACCTTCGGGTATTGAAAGCTGTTCCGGTTGCCGCTGTTCCGGTCGCCGCTGTTCGTCTCAATCGCACCTTCGGGTATTGAAAGTAAAGGCTGTATCAGCAAAGAAGATAACCGGCTCATGTCTCAATCGCACCTTCGGGTATTGAAAGGGCAATGTTTTTACCGTTGTACCAGGACCGGAACGTGGTCTCAATCGCACCTTCGGGTATTGAAAGGTACAGATACACCCGACTAGACACGGCATCACTGAGGTCTCAATCGCACCTTCGGGTATTGAAAGAAGTCGTAAACGGCAACGTGCGGCCTGTCTATAAATAGTCTCAATCGCACCTTCGGGTATTGAAAGGACTCCCAAAACGCGATCCCTGTTCAAGCTGTAGAAGTCTCAATCGCACCTTCGGGTATTGAAAGTTAATGTCCTTGCTTGGTTTTGGGAGGAGGGAGCCGTCTCAATCGCACCTTCGGGTATTGAAAGGCCACGTGCTGGTCAAAGTCGCTATCGACAATAACGTCTCAATCGCACCTTCGGGTATTGAAAGTAATAAACAGCGGTGTCGTTGGGTCCTTGGCTACGCCGTCTCAATCGCACCTTCGGGTATTGAAAGAATTTTTAGGGGTAATGGGCCGCTCGCAAATGCTAAGTCTCAATCGCACCTTCGGGTATTGAAAGGGAAGATAAGTGGGATTGCGATGCCAATTTAGTCATGTCTCAATCGCACCTTCGGGTATTGAAAGGTAAGCCGGACGCGCTGGCCAGGGGTGAACGCGGGGGGTCTCAATCGCACCTTCGGGTATTGAAAGATGGGTTTTGAGTCGCACAAGTTGCGGAATGGCGTTGTCTCAATCGCACCTTCGGGTATTGAAAGGTTGGTGCTATACGTACTAGCTGGCAACGCTGCGTTGGTCTCAATCGCACCTTCGGGTATTGAAAGGGTGTATCAAAACCAGCAAAAGCATCTACCATGTACTGTCTCAATCGCACCTTCGGGTATTGAAAGCTGTGCCCTGCGTCGTGGCCGGGTAATCGATCATGGGTCTCAATCGCACCTTCGGGTATTGAAAGTAGAAGATGACACCGCTAAGCTGTGCGGCAAAAACAGTCTCAATCGCACCTTCGGGTATTGAAAGGTGTTTACCGATGAGGAAGCGAACCGAAAGTATCTGGGTCTCAATCGCACCTTCGGGTATTGAAAGAGGGGTTGAGCGATACGTCTTTGCTGATCATTACGCGTCTCAATCGCACCTTCGGGTATTGAAAGCTGACAATACCGCCTGCTCTGATGTCCCGAATGGGTCTCAATCGCACCTTCGGGTATTGAAAGGCGATATGATTGCGTTTAGCCGGGAATACGTGCTACGTCTCAATCGCACCTTCGGGTATTGAAAGCCGTCGATGAGGATGATGCTGTGCTGACGCTCGAGCTGGGTCTCAATCGCACCTTCGGGTATTGAAAGTTAATGTTTCGGCGCTGCTGACCCAGCCTTCGGTCAGTCTCAATCGCACCTTCGGGTATTGAAAGGGGCGAAATGCCCTTGAGAAAATACGCATGCAGGGCGTCTCAATCGCACCTTCGGGTATTGAAAGGCGAAATTCAGCACCAGTGCGCCCAGCCGGGTGTCGTCTCAATCGCACCTTCGGGTATTGAAAGCACGTACTCAGTAGGTGGTACCTTCCAAGGTCAGCCGTCTCAATCGCACCTTCGGGTATTGAAAGTTACTTTAGTTGGTATTGTAAGATTTGACATCTTGTGTCTCAATCGCACCTTCGGGTATTGAAAGGAATTGTTAAACGTTCCAGGTTTCGCAGGTATACGACGTCTCAATCGCACCTTCGGGTATTGAAAGCTGACAATACCGCCTGCTCTGATGTCCCGAATGGGTCTCAATCGCACCTTCGGGTATTGAAAGGTAACGACAAGTCGAATGCTGGGCCACCTATTCGTGTCTCAATCGCACCTTCGGGTATTGAAAGTTTTCCAACCTGTATCACTCCATCCATTACCGGATAACATAAGTCTCAATCGCACCTTCGGGTATTGAAAGCCTAGAAAGCACGATGCCTAATGGGAAGGTGATTGAGTCTCAATCGCACCTTCGGGTATTGAAAGAACGGCGTGGGGCTTAAGGGCGAAATGTACGTGGGGTCTCAATCGCACCTTCGGGTATTGAAAGCATAGCTTTTCCTAGCAACAATTTGATTTATCGTCGGTCTCAATCGCACCTTCGGGTATTGAAAGGTGATAAAGCGGGTCTGACCAGCGCCTGTACCCGACGTCTCAATCGCACCTTCGGGTATTGAAAGGGCAACTAGAGCAGGGGGCGACTTCTGGCAGATAATGGTCTCAATCGCACCTTCGGGTATTGAAAGGTAGCCGACCAGGTTGGACTCATATCTGCGTTTACTGTCTCAATCGCACCTTCGGGTATTGAAAGCTACATACGACCGGTGCTTAATCCCGTTTTAATTTTAGTCTCAATCGCACCTTCGGGTATTGAAAGACGAATTACGTAAGCCTCCTCCGATAAGTTTAACTCGTCTCAATCGCACCTTCGGGTATTGAAAGCAAAGTTGCTTAAGGGCGTAACGTTCGTTAATCGGACGGTCTCAATCGCACCTTCGGGTATTGAAAGTAAGCGGTTGCCTCTGCTGCTACGAAAGGCAAAACAGGTCTCAATCGCACCTTCGGGTATTGAAAGGCGTTCACCCCAGGGCGAATAAAATCATCTATACCTCGTCTCAATCGCACCTTCGGGTATTGAAAGCCCTGATGGGGTGCCCGTGCCAAAGTGCATATATAGCGTCTCAATCGCACCTTCGGGTATTGAAAGGCTATGAGCTTTCTGCTGGATGAACGCTGCGTGCTGTGTCTCAATCGCACCTTCGGGTATTGAAAGTTCGTCTCCTTTGTTGAGTATAAATTTACAGCCTACCGTCTCAATCGCACCTTCGGGTATTGAAAGTACTGGTTATTGATCCCCATGTATTCGATTCGGTTATGTCTCAATCGCACCTTCGGGTATTGAAAGGAGTGCCTTAACCAGCTTACGGGGTAAGTTTACTCAGGTCTCAATCGCACCTTCGGGTATTGAAAGGCGGTTTAGATTCATCATTCGTTGAGTTTTCCTTTCCAGTCTCAATCGCACCTTCGGGTATTGAAAGGACGTAGGCCGGCACCTCGGGCGGCTCATAGCCAACGTCTCAATCGCACCTTCGGGTATTGAAAG

>NZ_CP025096|2|1|2327801-2332861|PILER-CR
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTACTTGGGTCGAGTTCACCACTCAGTACAACATCCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAAGACGCGCTGAGCAATGGCCGCGCTGGTTGCTGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GATAACTGCTTCGGCAACTTTCTGACCCAGATAGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CATCCGAATCTGGATCGGGCAAGGGTGAAGCGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCATCGGGATTCGTTGTGGCAAACGTGCTGGCTGGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTGTACTGGCGGGCAAACGCTGCCCATTTTTGGCCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGCTTAATATCTCGGTACAAATTGAATTGAATCGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTATTAATACCGGCTGTGCCCCCTTCTCTCCCAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TGGGTTTTTCTTCGCCTCCAACCGGGAAGTGTCGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTATGTAGGTATTGGTAACGTAGTTGAAGTTGTTGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TCCTATGGTAGTTGATGATCGCTTTGTAATAGCGAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTATTCAAACGCGACTCGGTCGGCAAGGCCAGCGGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TCCGGTGCCTGCGTGGTCGTATAGTCACTTCTGGCCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGTTTGAGGGTGAACTATCGGGCAGACTGCCAGCTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAAAAACAGGTGCATGTGCCCATTGGGGCCATTAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTACGCATCGCTGGCAGGCATGGCGGGCGTTTTCCT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGATAAGGCCCCCGATGAGGTTGCCCATACCCTCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	ACGAAAGCGTAACCCGGCTGTATCTGGATACCAAGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAATGAGGGCTTTACCAATGGCGGCATAATAATTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAATGAGGGCTTTACCAATGGCGGCATAATAATTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAGCGGATTGAATTGCGCTGGCGGTATCGGTCTTT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTATTGAGGGGAAGGTTGGTTACAGGCAACTGGAAAAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTATTTTAAAAATGCCGGAATCAAAAAAGGTTGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGGCTGTATCGCCTATAGCCGTGACTTCACAGACGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGGAAAGAAAAAAGCGCCGGATAGTTTTATTGAGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTGAGAATGATTGTATCGTCAATAAAATGTCCGACATAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGTTAAGCCATGACCGCTACGGAGTGACTTATCATTCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TGTAGGTGGTAAAGCCCGTCAGTACCACATTGGAAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGTTCCGGTTGCCGCTGTTCCGGTCGCCGCTGTTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAAAGGCTGTATCAGCAAAGAAGATAACCGGCTCAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGCAATGTTTTTACCGTTGTACCAGGACCGGAACGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTACAGATACACCCGACTAGACACGGCATCACTGAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	AAGTCGTAAACGGCAACGTGCGGCCTGTCTATAAATA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GACTCCCAAAACGCGATCCCTGTTCAAGCTGTAGAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTAATGTCCTTGCTTGGTTTTGGGAGGAGGGAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCCACGTGCTGGTCAAAGTCGCTATCGACAATAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAATAAACAGCGGTGTCGTTGGGTCCTTGGCTACGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	AATTTTTAGGGGTAATGGGCCGCTCGCAAATGCTAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGAAGATAAGTGGGATTGCGATGCCAATTTAGTCAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAAGCCGGACGCGCTGGCCAGGGGTGAACGCGGGGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	ATGGGTTTTGAGTCGCACAAGTTGCGGAATGGCGTT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTTGGTGCTATACGTACTAGCTGGCAACGCTGCGTTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGTGTATCAAAACCAGCAAAAGCATCTACCATGTACT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGTGCCCTGCGTCGTGGCCGGGTAATCGATCATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAGAAGATGACACCGCTAAGCTGTGCGGCAAAAACA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTGTTTACCGATGAGGAAGCGAACCGAAAGTATCTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	AGGGGTTGAGCGATACGTCTTTGCTGATCATTACGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGACAATACCGCCTGCTCTGATGTCCCGAATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGATATGATTGCGTTTAGCCGGGAATACGTGCTAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCGTCGATGAGGATGATGCTGTGCTGACGCTCGAGCTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTAATGTTTCGGCGCTGCTGACCCAGCCTTCGGTCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGGCGAAATGCCCTTGAGAAAATACGCATGCAGGGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGAAATTCAGCACCAGTGCGCCCAGCCGGGTGTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CACGTACTCAGTAGGTGGTACCTTCCAAGGTCAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTACTTTAGTTGGTATTGTAAGATTTGACATCTTGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GAATTGTTAAACGTTCCAGGTTTCGCAGGTATACGAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGACAATACCGCCTGCTCTGATGTCCCGAATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAACGACAAGTCGAATGCTGGGCCACCTATTCGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTTTCCAACCTGTATCACTCCATCCATTACCGGATAACATAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCTAGAAAGCACGATGCCTAATGGGAAGGTGATTGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	AACGGCGTGGGGCTTAAGGGCGAAATGTACGTGGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CATAGCTTTTCCTAGCAACAATTTGATTTATCGTCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTGATAAAGCGGGTCTGACCAGCGCCTGTACCCGAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGCAACTAGAGCAGGGGGCGACTTCTGGCAGATAATG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAGCCGACCAGGTTGGACTCATATCTGCGTTTACT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTACATACGACCGGTGCTTAATCCCGTTTTAATTTTA
GTCTCAATCGCACCTTCGGGTATTGAAAG	ACGAATTACGTAAGCCTCCTCCGATAAGTTTAACTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAAAGTTGCTTAAGGGCGTAACGTTCGTTAATCGGACG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAAGCGGTTGCCTCTGCTGCTACGAAAGGCAAAACAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGTTCACCCCAGGGCGAATAAAATCATCTATACCTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCCTGATGGGGTGCCCGTGCCAAAGTGCATATATAGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCTATGAGCTTTCTGCTGGATGAACGCTGCGTGCTGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTCGTCTCCTTTGTTGAGTATAAATTTACAGCCTACC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TACTGGTTATTGATCCCCATGTATTCGATTCGGTTAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GAGTGCCTTAACCAGCTTACGGGGTAAGTTTACTCAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGGTTTAGATTCATCATTCGTTGAGTTTTCCTTTCCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GACGTAGGCCGGCACCTCGGGCGGCTCATAGCCAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG

>NZ_CP025096|2|2|2327801-2332861|CRISPRCasFinder
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTACTTGGGTCGAGTTCACCACTCAGTACAACATCCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAAGACGCGCTGAGCAATGGCCGCGCTGGTTGCTGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GATAACTGCTTCGGCAACTTTCTGACCCAGATAGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CATCCGAATCTGGATCGGGCAAGGGTGAAGCGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCATCGGGATTCGTTGTGGCAAACGTGCTGGCTGGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTGTACTGGCGGGCAAACGCTGCCCATTTTTGGCCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGCTTAATATCTCGGTACAAATTGAATTGAATCGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTATTAATACCGGCTGTGCCCCCTTCTCTCCCAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TGGGTTTTTCTTCGCCTCCAACCGGGAAGTGTCGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTATGTAGGTATTGGTAACGTAGTTGAAGTTGTTGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TCCTATGGTAGTTGATGATCGCTTTGTAATAGCGAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTATTCAAACGCGACTCGGTCGGCAAGGCCAGCGGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TCCGGTGCCTGCGTGGTCGTATAGTCACTTCTGGCCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGTTTGAGGGTGAACTATCGGGCAGACTGCCAGCTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAAAAACAGGTGCATGTGCCCATTGGGGCCATTAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTACGCATCGCTGGCAGGCATGGCGGGCGTTTTCCT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGATAAGGCCCCCGATGAGGTTGCCCATACCCTCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	ACGAAAGCGTAACCCGGCTGTATCTGGATACCAAGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAATGAGGGCTTTACCAATGGCGGCATAATAATTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAATGAGGGCTTTACCAATGGCGGCATAATAATTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAGCGGATTGAATTGCGCTGGCGGTATCGGTCTTT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTATTGAGGGGAAGGTTGGTTACAGGCAACTGGAAAAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTATTTTAAAAATGCCGGAATCAAAAAAGGTTGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGGCTGTATCGCCTATAGCCGTGACTTCACAGACGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGGAAAGAAAAAAGCGCCGGATAGTTTTATTGAGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTGAGAATGATTGTATCGTCAATAAAATGTCCGACATAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGTTAAGCCATGACCGCTACGGAGTGACTTATCATTCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TGTAGGTGGTAAAGCCCGTCAGTACCACATTGGAAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGTTCCGGTTGCCGCTGTTCCGGTCGCCGCTGTTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAAAGGCTGTATCAGCAAAGAAGATAACCGGCTCAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGCAATGTTTTTACCGTTGTACCAGGACCGGAACGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTACAGATACACCCGACTAGACACGGCATCACTGAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	AAGTCGTAAACGGCAACGTGCGGCCTGTCTATAAATA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GACTCCCAAAACGCGATCCCTGTTCAAGCTGTAGAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTAATGTCCTTGCTTGGTTTTGGGAGGAGGGAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCCACGTGCTGGTCAAAGTCGCTATCGACAATAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAATAAACAGCGGTGTCGTTGGGTCCTTGGCTACGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	AATTTTTAGGGGTAATGGGCCGCTCGCAAATGCTAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGAAGATAAGTGGGATTGCGATGCCAATTTAGTCAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAAGCCGGACGCGCTGGCCAGGGGTGAACGCGGGGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	ATGGGTTTTGAGTCGCACAAGTTGCGGAATGGCGTT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTTGGTGCTATACGTACTAGCTGGCAACGCTGCGTTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGTGTATCAAAACCAGCAAAAGCATCTACCATGTACT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGTGCCCTGCGTCGTGGCCGGGTAATCGATCATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAGAAGATGACACCGCTAAGCTGTGCGGCAAAAACA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTGTTTACCGATGAGGAAGCGAACCGAAAGTATCTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	AGGGGTTGAGCGATACGTCTTTGCTGATCATTACGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGACAATACCGCCTGCTCTGATGTCCCGAATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGATATGATTGCGTTTAGCCGGGAATACGTGCTAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCGTCGATGAGGATGATGCTGTGCTGACGCTCGAGCTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTAATGTTTCGGCGCTGCTGACCCAGCCTTCGGTCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGGCGAAATGCCCTTGAGAAAATACGCATGCAGGGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGAAATTCAGCACCAGTGCGCCCAGCCGGGTGTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CACGTACTCAGTAGGTGGTACCTTCCAAGGTCAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTACTTTAGTTGGTATTGTAAGATTTGACATCTTGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GAATTGTTAAACGTTCCAGGTTTCGCAGGTATACGAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGACAATACCGCCTGCTCTGATGTCCCGAATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAACGACAAGTCGAATGCTGGGCCACCTATTCGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTTTCCAACCTGTATCACTCCATCCATTACCGGATAACATAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCTAGAAAGCACGATGCCTAATGGGAAGGTGATTGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	AACGGCGTGGGGCTTAAGGGCGAAATGTACGTGGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CATAGCTTTTCCTAGCAACAATTTGATTTATCGTCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTGATAAAGCGGGTCTGACCAGCGCCTGTACCCGAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGCAACTAGAGCAGGGGGCGACTTCTGGCAGATAATG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAGCCGACCAGGTTGGACTCATATCTGCGTTTACT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTACATACGACCGGTGCTTAATCCCGTTTTAATTTTA
GTCTCAATCGCACCTTCGGGTATTGAAAG	ACGAATTACGTAAGCCTCCTCCGATAAGTTTAACTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAAAGTTGCTTAAGGGCGTAACGTTCGTTAATCGGACG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAAGCGGTTGCCTCTGCTGCTACGAAAGGCAAAACAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGTTCACCCCAGGGCGAATAAAATCATCTATACCTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCCTGATGGGGTGCCCGTGCCAAAGTGCATATATAGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCTATGAGCTTTCTGCTGGATGAACGCTGCGTGCTGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTCGTCTCCTTTGTTGAGTATAAATTTACAGCCTACC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TACTGGTTATTGATCCCCATGTATTCGATTCGGTTAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GAGTGCCTTAACCAGCTTACGGGGTAAGTTTACTCAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGGTTTAGATTCATCATTCGTTGAGTTTTCCTTTCCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GACGTAGGCCGGCACCTCGGGCGGCTCATAGCCAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG

>NZ_CP025096|2|1|2327801-2332861|CRT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTACTTGGGTCGAGTTCACCACTCAGTACAACATCCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAAGACGCGCTGAGCAATGGCCGCGCTGGTTGCTGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GATAACTGCTTCGGCAACTTTCTGACCCAGATAGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CATCCGAATCTGGATCGGGCAAGGGTGAAGCGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCATCGGGATTCGTTGTGGCAAACGTGCTGGCTGGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTGTACTGGCGGGCAAACGCTGCCCATTTTTGGCCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGCTTAATATCTCGGTACAAATTGAATTGAATCGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTATTAATACCGGCTGTGCCCCCTTCTCTCCCAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TGGGTTTTTCTTCGCCTCCAACCGGGAAGTGTCGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTATGTAGGTATTGGTAACGTAGTTGAAGTTGTTGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TCCTATGGTAGTTGATGATCGCTTTGTAATAGCGAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTATTCAAACGCGACTCGGTCGGCAAGGCCAGCGGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TCCGGTGCCTGCGTGGTCGTATAGTCACTTCTGGCCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGTTTGAGGGTGAACTATCGGGCAGACTGCCAGCTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAAAAACAGGTGCATGTGCCCATTGGGGCCATTAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTACGCATCGCTGGCAGGCATGGCGGGCGTTTTCCT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGATAAGGCCCCCGATGAGGTTGCCCATACCCTCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	ACGAAAGCGTAACCCGGCTGTATCTGGATACCAAGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAATGAGGGCTTTACCAATGGCGGCATAATAATTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCAATGAGGGCTTTACCAATGGCGGCATAATAATTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAGCGGATTGAATTGCGCTGGCGGTATCGGTCTTT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTATTGAGGGGAAGGTTGGTTACAGGCAACTGGAAAAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTATTTTAAAAATGCCGGAATCAAAAAAGGTTGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGGCTGTATCGCCTATAGCCGTGACTTCACAGACGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGGAAAGAAAAAAGCGCCGGATAGTTTTATTGAGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTGAGAATGATTGTATCGTCAATAAAATGTCCGACATAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGTTAAGCCATGACCGCTACGGAGTGACTTATCATTCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TGTAGGTGGTAAAGCCCGTCAGTACCACATTGGAAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGTTCCGGTTGCCGCTGTTCCGGTCGCCGCTGTTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAAAGGCTGTATCAGCAAAGAAGATAACCGGCTCAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGCAATGTTTTTACCGTTGTACCAGGACCGGAACGTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTACAGATACACCCGACTAGACACGGCATCACTGAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	AAGTCGTAAACGGCAACGTGCGGCCTGTCTATAAATA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GACTCCCAAAACGCGATCCCTGTTCAAGCTGTAGAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTAATGTCCTTGCTTGGTTTTGGGAGGAGGGAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCCACGTGCTGGTCAAAGTCGCTATCGACAATAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAATAAACAGCGGTGTCGTTGGGTCCTTGGCTACGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	AATTTTTAGGGGTAATGGGCCGCTCGCAAATGCTAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGAAGATAAGTGGGATTGCGATGCCAATTTAGTCAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAAGCCGGACGCGCTGGCCAGGGGTGAACGCGGGGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	ATGGGTTTTGAGTCGCACAAGTTGCGGAATGGCGTT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTTGGTGCTATACGTACTAGCTGGCAACGCTGCGTTG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGTGTATCAAAACCAGCAAAAGCATCTACCATGTACT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGTGCCCTGCGTCGTGGCCGGGTAATCGATCATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAGAAGATGACACCGCTAAGCTGTGCGGCAAAAACA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTGTTTACCGATGAGGAAGCGAACCGAAAGTATCTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	AGGGGTTGAGCGATACGTCTTTGCTGATCATTACGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGACAATACCGCCTGCTCTGATGTCCCGAATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGATATGATTGCGTTTAGCCGGGAATACGTGCTAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCGTCGATGAGGATGATGCTGTGCTGACGCTCGAGCTGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTAATGTTTCGGCGCTGCTGACCCAGCCTTCGGTCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGGCGAAATGCCCTTGAGAAAATACGCATGCAGGGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGAAATTCAGCACCAGTGCGCCCAGCCGGGTGTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CACGTACTCAGTAGGTGGTACCTTCCAAGGTCAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTACTTTAGTTGGTATTGTAAGATTTGACATCTTGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GAATTGTTAAACGTTCCAGGTTTCGCAGGTATACGAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTGACAATACCGCCTGCTCTGATGTCCCGAATGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAACGACAAGTCGAATGCTGGGCCACCTATTCGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTTTCCAACCTGTATCACTCCATCCATTACCGGATAACATAA
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCTAGAAAGCACGATGCCTAATGGGAAGGTGATTGA
GTCTCAATCGCACCTTCGGGTATTGAAAG	AACGGCGTGGGGCTTAAGGGCGAAATGTACGTGGG
GTCTCAATCGCACCTTCGGGTATTGAAAG	CATAGCTTTTCCTAGCAACAATTTGATTTATCGTCG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTGATAAAGCGGGTCTGACCAGCGCCTGTACCCGAC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GGCAACTAGAGCAGGGGGCGACTTCTGGCAGATAATG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GTAGCCGACCAGGTTGGACTCATATCTGCGTTTACT
GTCTCAATCGCACCTTCGGGTATTGAAAG	CTACATACGACCGGTGCTTAATCCCGTTTTAATTTTA
GTCTCAATCGCACCTTCGGGTATTGAAAG	ACGAATTACGTAAGCCTCCTCCGATAAGTTTAACTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CAAAGTTGCTTAAGGGCGTAACGTTCGTTAATCGGACG
GTCTCAATCGCACCTTCGGGTATTGAAAG	TAAGCGGTTGCCTCTGCTGCTACGAAAGGCAAAACAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGTTCACCCCAGGGCGAATAAAATCATCTATACCTC
GTCTCAATCGCACCTTCGGGTATTGAAAG	CCCTGATGGGGTGCCCGTGCCAAAGTGCATATATAGC
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCTATGAGCTTTCTGCTGGATGAACGCTGCGTGCTGT
GTCTCAATCGCACCTTCGGGTATTGAAAG	TTCGTCTCCTTTGTTGAGTATAAATTTACAGCCTACC
GTCTCAATCGCACCTTCGGGTATTGAAAG	TACTGGTTATTGATCCCCATGTATTCGATTCGGTTAT
GTCTCAATCGCACCTTCGGGTATTGAAAG	GAGTGCCTTAACCAGCTTACGGGGTAAGTTTACTCAG
GTCTCAATCGCACCTTCGGGTATTGAAAG	GCGGTTTAGATTCATCATTCGTTGAGTTTTCCTTTCCA
GTCTCAATCGCACCTTCGGGTATTGAAAG	GACGTAGGCCGGCACCTCGGGCGGCTCATAGCCAAC
GTCTCAATCGCACCTTCGGGTATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100987821.1\|2322230_2323151_+\|type-I-PGING-CRISPR-associated-protein-Cas7/Csp1	cas7b	cd09717_cas7b_CAS-I-B	gnl\|CDD\|132528
NZ_CP025096.1\|WP_100987832.1\|2338649_2338892_-\|TraR/DksA-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|224648
NZ_CP025096.1\|WP_100987817.1\|2318011_2318929_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP025096.1\|WP_100987822.1\|2323152_2325612_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NZ_CP025096.1\|WP_100987833.1\|2339867_2342390_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226702
NZ_CP025096.1\|WP_100987828.1\|2335539_2336067_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100987824.1\|2326203_2327289_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP025096.1\|WP_097124292.1\|2333476_2333668_-\|cold-shock-domain-containing-protein	unknown	unknown	gnl\|CDD\|239905
NZ_CP025096.1\|WP_100987826.1\|2334053_2334329_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235351
NZ_CP025096.1\|WP_100987831.1\|2337860_2338583_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|365969
NZ_CP025096.1\|WP_100987816.1\|2316800_2317799_+\|DUF1016-domain-containing-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl\|CDD\|377634
NZ_CP025096.1\|WP_100987825.1\|2327318_2327582_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP025096.1\|WP_100987830.1\|2337499_2337883_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100987829.1\|2336166_2336760_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100987834.1\|2342765_2345156_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|274576
NZ_CP025096.1\|WP_100987818.1\|2319070_2319736_+\|CRISPR-associated-protein-Cas6	unknown	unknown	gnl\|CDD\|224499
NZ_CP025096.1\|WP_100987820.1\|2320565_2322218_+\|hypothetical-protein	cas8b4	cd09715_cas8b4_CAS-I-B	gnl\|CDD\|187846
NZ_CP025096.1\|WP_100987827.1\|2334896_2335451_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100987823.1\|2325598_2326156_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP025096.1\|WP_100987819.1\|2319747_2320569_+\|hypothetical-protein	cas5	cd09716_cas5_CAS-I-B	gnl\|CDD\|132527

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100987821.1\|2322230_2323151_+\|type-I-PGING-CRISPR-associated-protein-Cas7/Csp1	gnl\|CDD\|132528	TIGR03489, cas_csp1, CRISPR-associated protein Cas7/Csp1, subtype PGING. Members of this protein family are Csp1, a CRISPR-associated (cas) gene marker for the Pging subtype of CRISPR/cas system, as found in Porphyromonas gingivalis W83 and Bacteroides forsythus ATCC 43037. This protein belongs to the family of DevR (TIGR01875), a regulator of development in Myxococcus xanthus located in a cas gene region. A different branch of the DevR family, Cst2 (TIGR02585), is a marker for the Tneap subtype of CRISPR/cas system.	4.07866e-111
NZ_CP025096.1\|WP_100987832.1\|2338649_2338892_-\|TraR/DksA-C4-type-zinc-finger-protein	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.73243e-08
NZ_CP025096.1\|WP_100987817.1\|2318011_2318929_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	5.71968e-29
NZ_CP025096.1\|WP_100987822.1\|2323152_2325612_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	1.60757e-76
NZ_CP025096.1\|WP_100987833.1\|2339867_2342390_-\|PAS-domain-containing-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	1.00818e-58
NZ_CP025096.1\|WP_100987824.1\|2326203_2327289_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	8.49284e-151
NZ_CP025096.1\|WP_097124292.1\|2333476_2333668_-\|cold-shock-domain-containing-protein	gnl\|CDD\|239905	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription.	1.85556e-25
NZ_CP025096.1\|WP_100987826.1\|2334053_2334329_+\|hypothetical-protein	gnl\|CDD\|235351	PRK05137, tolB, Tol-Pal system protein TolB.	0.00169239
NZ_CP025096.1\|WP_100987831.1\|2337860_2338583_+\|recombinase-family-protein	gnl\|CDD\|365969	pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.	2.2175e-22
NZ_CP025096.1\|WP_100987816.1\|2316800_2317799_+\|DUF1016-domain-containing-protein	gnl\|CDD\|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	7.28137e-75
NZ_CP025096.1\|WP_100987825.1\|2327318_2327582_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.46278e-23
NZ_CP025096.1\|WP_100987834.1\|2342765_2345156_+\|ABC-transporter-permease	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	2.31878e-67
NZ_CP025096.1\|WP_100987818.1\|2319070_2319736_+\|CRISPR-associated-protein-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	3.34891e-06
NZ_CP025096.1\|WP_100987820.1\|2320565_2322218_+\|hypothetical-protein	gnl\|CDD\|187846	cd09715, Csp2_I-U, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Predicted Cas8 ortholog.	2.71487e-72
NZ_CP025096.1\|WP_100987823.1\|2325598_2326156_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	4.75731e-50
NZ_CP025096.1\|WP_100987819.1\|2319747_2320569_+\|hypothetical-protein	gnl\|CDD\|132527	TIGR03488, cas_Cas5p, CRISPR-associated protein Cas5, subtype PGING. CC Members of this protein family are cas, or CRISPR-associated, proteins. The two sequences in the alignment seed are found within cas gene clusters that are adjacent to CRISPR DNA repeats in two members of the order Bacteroidales, Porphyromonas gingivalis W83 and Bacteroides forsythus ATCC 43037. This cas protein family is unique to the Pgingi (Porphyromonas gingivalis) subtype, but shows some sequence similarity to genes of the Cas5 type (see TIGR02593).	9.74291e-21

>NZ_CP025096.1|WP_100987825.1|2327318_2327582_+|CRISPR-associated-endonuclease-Cas2
MPFCIAVYDVNQKRTGKMLKLFRRYLTWVQNSVFEGDLTPAQLKHLQQEADVLLQDNDGVVFYQLRDERYVERIALGVDITNRSRFL
>NZ_CP025096.1|WP_100987824.1|2326203_2327289_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKPHYLFSSGRLRRQHNTLALERATGERSPDDDPTDEGLPSVTPDGKNHPFPVETVDSLYIFGEVDINTKLITFLGQQGIPAFFYDYYGYYTATLYPRESQLSGRLRVDQARHYLSPKRRLVLARAFVESALFNIERVIKYYQPRLSGDEQLTVQKALLDLKRDRDALPLTVDIPTLMAVEGRIRDRYYRLWPYFLGTDVVARFPFNKRERRPPSNELNALISFGNSLCYTTVLRQIYRTALDPTVAFLHEPGDRRFSLALDLAEVFKPLLVDRMIFRLLKTAELTPKHFEKHLGGCYLSEAGRKIVVGHWDERLSQTVQHRTMNKRVSYERLIRLECYKLVRHLCDPVGEAYQGFHMWW
>NZ_CP025096.1|WP_100987823.1|2325598_2326156_+|CRISPR-associated-protein-Cas4
MTTTNSSKLRIGGMLVGYYRLCPRKAWLSMRGIWMEQESDTVALGRLLDEHSYDRSDKHIEINAEAPDGTPLVGKIDRANLKNGVLHETKKSRSCEDAHVWQVRFYLWLLTRNGVTRSDGSPFRGQLDYPLLRRTECITLEPEHTDELVATVSTIRALASQETPPARLLKRTFCTKCAFDELCYG
>NZ_CP025096.1|WP_100987822.1|2323152_2325612_+|CRISPR-associated-helicase-Cas3'
MVALAKPSGITLRDHVSHVQKHAIAILTVWPFLAEKYARLTNGKSLKDAVEKAIKWHDEGKRIDNWQAACQKDYAQYQEWLKTKNLDPLRIDATLYQQYEWEMKQQNKATGKHLRDAKFRHEFGSLKLAADKKAGLSVEEQTAIAAHHGKLGKRHLKRWESDGGGAFLIYWSKFINQERDQAKYDLDRWGKLLLARYEIAAVRSLLQLADTRASREESEGELAPLTEFDYEFPHGKGNERGVQKAAMELADQWCSILRAPTGSGKTDAALLWGQQQIENKRADRLIIAMPTRFTSNALALNIEKNVRNTGLYHSSARFTQTAKVQKDGKKISFEQKQYLNEQQRLAQLLATPVTVCTVDHLLISLTGAAEHHHSSFFFLANSAVVFDEADFYDPFVQANLTVLLKALRILHVPVLIMSATVPDSACALYDVPQGIKEPILNEEPPKRALAWAGKPTTVQVGETEYSDLPVTEKAKDVADVLQKMVDARHGIIYANTVERALMYYDWFNENAPNQEIILYHSRFTEPDKGLIEDRLLKTLGKDIWTKPNPTPLAIAILTQIGEMSVNISASIMLSDLCPWDRLTQRLGRLNRFGKPAEAVAYLTIPYKKEAVYVAPYGELIDRKWVPAPAFINTLASVVGMIPNGGLRPIKPAELVDVVNALYPDLPAFPEKAADNRDQLYNLMNQNWLIVPDRRLDEEAGTVSTAWRSRDIDEHRTILTRSPYDFKNYEEYQAFVLEFGVSCPVWMVEKEERRKENSRITVVEVLIDDEPEKLRYTDEYESWTEQDEGRIEGYVKPNKPKRGMAFLYDKKDTTPNDDDD
>NZ_CP025096.1|WP_100987821.1|2322230_2323151_+|type-I-PGING-CRISPR-associated-protein-Cas7/Csp1
MTIKSITVTLIAPMSDHAANRGEKLLGNASSIKRRPDGRVYISGQMQRHALFSAVERLNDDDPNGTYVANGDGPSTKIEIDLRSDLGGYLDTNKGEYSGRRTAPLTATPAVAITRSDIGRDLLVRLKQNADAESEQKQALATNEFSQRDDMVMSFHLDIGAVGVRKRYSYEKEQHIETQYDNFIKDDEHRRRVKLFLEATRSITDYANQARQATSGEPQKVLIVLDTKMSRKAARYFAPETSPEVQANIRAELTAREAQYFLGDDTQKPDEAKGHYSVDMAYEKATDALMAGTLYRPASMISKMPA
>NZ_CP025096.1|WP_100987820.1|2320565_2322218_+|hypothetical-protein
MINPNNWHPYPRYGLATAMVMLDNQLADFTDPIMLLKLGAKALRKGINAYSLRTLGDPKSDTKLSFTYLSGEDVNPGSANNQSSKFGYFLAPHILTSNNAAEAIKEIRQLLQLLDGTDVNPAKSYELKRSFAPMIAKLNNGNASMANPRVGLLEATFTAIATLTDLKPSVYAPHKKDEFCNFGIIPDLPLWDEQKPSHLPLIEFVEVFKDLTDTYAREPGEDKYIATVKPDKKAYARPSVFSGNYPGAAKGGTLGAISLVAAIGRWARQENTLLLGKPNNELARIVLIQLATRPLYIVSYEGIRQESFGHHLVDLALNSDLSDINQAFNKVRLLGIDEREKFKSTNWQNFRMMSDRFLRLYTPASFQDFLAFRAEYPASLKPLIEHYMTQQSDKLSPEIIKSARAYGESLNNAAFSAATEEMEDDARRQNKPKPTSEIKKTLDYRTKRNQYKDRILTQFESTVGSAKSSAALLSQLGTIAGRLTHREIKPEAGEFMEAVLTGDISIDDAKNLITAFMRLSTFKAATSEALGVVHEDDELETAETKTITED
>NZ_CP025096.1|WP_100987819.1|2319747_2320569_+|hypothetical-protein
MENIDLSFFLEPPVLDTAALLTIEALYPLSMVPAQPGAYYRSQAHPTDPMIFGMLENALGWHFGEKERSEFLKDLRKTASKKHNKQAKWKDSDWLSGRSSGSGSGFTSLLMYHMHVDTHWLPQVMEYDDLWSQHLHDVGANFMGGSKHYDGDLESLINRSKTPDTTKPINPKTKKYPPLIEFGESTTHQKLTREDATILPSGAVHFKSVRDGYPLYYVSPKRRGYVVPQSPYRYRIMTTLTLANLIQIALNDPASPLYLGSNDGWVDVNWEQL
>NZ_CP025096.1|WP_100987818.1|2319070_2319736_+|CRISPR-associated-protein-Cas6
MRLQLQLTPNTQPVPFDHLHQLTGALHKWLGQNNIHDGLSLYSFGWLRGGKPIGRNLYFLENATWSISFHDDSQAWQLARGILKDPMFAFGMKVEKATEMPLQTGFTQISFKVDGMVVARRKRPDGSKEYLLWDNPAADEVLTGIFRQKLTAAGFGPEHLSATVQFDRNFANARTKIATIKSIKHKGSECPVIVTGTPEAVHFVQLVGVGDLTGSGFGALL
>NZ_CP025096.1|WP_100987817.1|2318011_2318929_+|WYL-domain-containing-protein
MNDSAKLRRQLHLIRCLDKPYTYPSLIQVHKYLLDHDIEQTSLATVERDINDIRTDYDISIIYDRRRHGYFLDLPTDDEDISNFREFVRLLERRERLELLTRSGRSVAQYIQLEQHNGFRGLDLMAPLWNALQRKLVITFSYQAYKDKPAEKRWVEPGLLFEYRNRWYLDGFDLDRNGERTFGLDRIIDLTLTPQSILPSRQTDYRAARRHVIGVTAPPGSSIEHVILRFRRPEAEYILSLPLHNSQQTLAETPTYVDIEIQVVLNHELEREILAYGEEVEVLAPACLRETMARRYSNVMKHYDS
>NZ_CP025096.1|WP_100987816.1|2316800_2317799_+|DUF1016-domain-containing-protein
MDQLVSEIRQIISQSRESAARSINHALALMYWHIGRVIVEDEQQGQERATYGKALIKNLSIQLVAEYGENFSSRNLQLSRQFYLTFPIVNSVSSQLTWTHYKVLVRLDDTSKRAFYMAETEKNAWTVRQLERQINSLLYERLLMSQDKESVLAIAQSEAKPTHPHQVIKDPIVLEFLGLKPQASYYEQDIEAAIITHIQEFLLELGNGFSFVARQKRIIIESDEFKIDLVFYNRLLQCFVLLDLKMDKITHQDLGQLQMYVNYYDRDIKESYENPTIGVLLCADKNDAVVRYTLPANNTQLFASKYQLHLPTEQQLINEIRKELPNDQTDQR
>NZ_CP025096.1|WP_097124292.1|2333476_2333668_-|cold-shock-domain-containing-protein
MPTGSVKFFNESKGFGFIKPDDGGEDVFVHISATSEELRENDKVTYNVEQGKKGLNAVNVKRT
>NZ_CP025096.1|WP_100987826.1|2334053_2334329_+|hypothetical-protein
MEKELGAKNLVQFRLTGTPDGNLLVSFYQLDVFNEKAVNWHIAGLLVENKLGARVLYEGNLSNNTAYQTAVHNLLERVNVYVNCVRIEIVK
>NZ_CP025096.1|WP_100987827.1|2334896_2335451_-|hypothetical-protein
MKCKCILWIGLVASVMTSCGKNETQLQPQVGGRNQHDQLIDQQFTGTWKLSSIKTSEPIDANLDGVASTDLMIEIPDHAYVIAQLKVNWLTQKRVFSDGYIRTYPATQANGNTAQYVVNGRTLFFDVNENRTQISLTDESQTKAYPLTYTNADEFRIDGVERTYNTKSGWKTIPTISTYQRVKQ
>NZ_CP025096.1|WP_100987828.1|2335539_2336067_-|hypothetical-protein
MAIRRKPISTDTIIAIAATFTSICALIVTLYQTKLTREQQLNSVWPYLIANEIVDENGLSSITIANSGIGPAIIDSVQVFYKGRLYRSPTAVVQALSEEQQRGRDGMSWYQTALEKGFVISQGQSLNWITVNGQTDNALFRKALPNIRAIIFYHSIYDEHWHSTFNGKGDVVVKD
>NZ_CP025096.1|WP_100987829.1|2336166_2336760_-|hypothetical-protein
MTPKQTQRLIKKIADIKRALAAEKRTFGGYDDSRGLRYLPTRYYIQLADYKGGLVYTRWFAKTFPDDIVFPDFLFEWAVLLFKAGKFAEAKAKIWQTFCANTYLFDKYFGHPIQPLPIYEWSNLAQAGFTDYFTYSHQQSELLDFSQWLEEFMVSEPFTTRKARYLILHQQLKMEDDLERRDYLRQEADQLENAIKF
>NZ_CP025096.1|WP_100987830.1|2337499_2337883_+|hypothetical-protein
MDAEVAKRVVYQLAFNWVQLNLPTDRLTYTDYINAIGGLQVITDDPTRTKAIFSAILDQANELGYSSEWVEVELKFEAQAEAVGDRAKWLRLDVAAREASDESLDLYNLRVSRFISKPGSNGKESND
>NZ_CP025096.1|WP_100987831.1|2337860_2338583_+|recombinase-family-protein
MAKKATIDNRPLEQDVHKKYVLYFRVSTKKQGESGLGLEAQRAYIDYFYKDKRILAEFTEIRSGKTIHKRPELQKAIALCKREGATLVVAKIDRLSRNTENALHIYKELGERLESCDIPNLDKFTLTLFMAIADRERVLISIRTQQAVEARRVRVGEWRVGGANAKKAAAGLRGAQLSRELAEENENSRRASAFINMLRSTGKTYEQIAEQLNLAGFRTPRGSNFHKMQVQRLIKRIESN
>NZ_CP025096.1|WP_100987832.1|2338649_2338892_-|TraR/DksA-C4-type-zinc-finger-protein
MYCIKCGNSIPEARLKALPTAKTCVHCSAAQRVAGFPLITGKTEYSALQIVSQADAQQLHKMGARRGTGASTYMKREKRN
>NZ_CP025096.1|WP_100987833.1|2339867_2342390_-|PAS-domain-containing-protein
MLSKATTPVNAYPFLSGGGELGELTRQYDWQTTSLGTPDGWPQSLRATLSILLNTKSPMFLWWGSDLIQFYNDAYRPSLGDKGKHPTALGQQGADCWPEIWPTIKPLIDQVLGGGEAIWNEDQLIPIYRNGQLEDVYWTFGYSAVKDESGQAAGVLVICTETTGAVLDRNKLKTSENRFRSIVEQAPVAVALFSGPAFVITLANERVLQFWGRSRQQVINKPLFEALPEASGQGFEELLHGVYTTGERFVASELPVTLERNGRMEQTFINFVYDPYYESDGTISGIIVLCVEITQQVTARKAIEESEAKFRSLVEEAPVATCLFVGRDLKIEVANEIMLGYWGKDSSVLGQPLAKAIPELAGQPFLAILDEVFTSGKAYESRGTRAELEVDGLLGAYYFDFSYKPLLNASGEIYAIMQMAVDVTEQVLAEQQSKASESRFRSIVEQAPMAIGLFSGREMVIEIGNDLIFEVWDKDPSIIGLPVIEALPEIKGQGYIELLEGVYDSGEPFSGANLLVELNRRGQLEDVYFDLLYTPLRDSFGIITGVMVLANEVTERVLSRQRLEQSESRYRLLSTELEQQVHQRTQQLQASVHDLERSNTNLQQFAYIASHDLQEPLRKIQSFGDLLKSQYGVELGDGVDYLQRMQTAASRMSILIRDLLTYSRIATGQESSQPVWLTDVLKRTLADLDLLIEETGASVRVDSLPTVWGNSSQLNQLFQNLLSNALKFNRVGVLPQIRISCQSVAAIDLPSSVKPTRRAAAYYRIDVSDNGIGFEEQYLDRIFQVFQRLNGKSQYAGTGIGLAICEKVMANHGGAITARSQPGQGATFCVYFPDQIISAG
>NZ_CP025096.1|WP_100987834.1|2342765_2345156_+|ABC-transporter-permease
MLRNYLKTAWRSLRYQRRYTTLNVLGLTIGMTGGLLIFLFVRHHLSTDRHQAKFDRIYRIVYDQHLPDGSVEYAAEAPWPMANALRSSLASGQQAAFLSMNRELTLSLNVPGQGVKQFLMHAGSAFVEPEWFNVFDYRWLTGNPKTALSQPNTIVFTQSWASRYFGSSNPIGQRVRLNDKVDVTVTGVLADPTGVTDLDLGIFISAATLPTLKPEYNVDDWSVLNSTDRVFVVFTDARSLSGLQTTLARITTQNYGLKPMVNFQAQPLADVHFDVKRRGGVIRSSMLWSLAVVGLLLVFTACINFINLATAQALRRGKEVGVRKTLGSSQRQLATQFLIETGIITLGSLLLAGLLTALLLPLFSSWTKTPVHVYLDAQTSLFLMALISSVILLAGGYPALVLSRLKPILALRGKLTAQAVGGLSLRQLLVGVQFVIGQLLLIGAIIVTAQMHYIQQADIGFQKENIVLVNLPTGQPSTQQAFKNELRNYPTVKEVSIGFLPPSTPGMYGGPFKFGNRAQEEKFPIRERFADADYLNTYGLTLIAGRNLTPSDTIKEYVVNEALVRKLGIRDPQRIIGQTMQYYMSGVALPIVGVVKDFHLQSLHEAVQPCFIAARADLYRQAGIRLAGQDVPQSLRQIEQSWQKFYPNQVFDPTFLDGTLAQYYEMETLISRLVDTASLVAILIGCLGLYGLVTFVVIQRTKEIGVRKVLGASVTSLVALLAKDFLKLVLVAFVIAVPLGWYLMNQWLQGFAYKTRVEWWYFGLAGLAMLGVALVTVSFHSIKAALVNPVQSLKSE

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Crispr_ID: NZ_CP025096_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_3

4674584-4674656

Unclear

Consensus_repeat	Method
CCCCCTCCTAAAACAGGAGGGGG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP025096_3

>merge|NZ_CP025096|3|4674584-4674656|CRISPRCasFinder
CCCCCTCCTAAAACAGGAGGGGGCTTAAAAAAGGGTAGCCCGTTAAGGAGCCCCCTCCTAAAACAGGAGGGGG

>NZ_CP025096|3|3|4674584-4674656|CRISPRCasFinder
CCCCCTCCTAAAACAGGAGGGGG	CTTAAAAAAGGGTAGCCCGTTAAGGAG
CCCCCTCCTAAAACAGGAGGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100989904.1\|4681264_4681744_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NZ_CP025096.1\|WP_100989899.1\|4669550_4672808_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP025096.1\|WP_100989910.1\|4687124_4688201_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100989902.1\|4677761_4678847_+\|gluconolactonase	unknown	unknown	gnl\|CDD\|308585
NZ_CP025096.1\|WP_100989908.1\|4684306_4686409_+\|TonB-dependent-receptor-plug-domain-containing-protein	unknown	unknown	gnl\|CDD\|238657
NZ_CP025096.1\|WP_100989893.1\|4658671_4661140_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|350795
NZ_CP025096.1\|WP_100989900.1\|4672847_4674530_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|185760
NZ_CP025096.1\|WP_100989898.1\|4666522_4667677_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274824
NZ_CP025096.1\|WP_100989901.1\|4676539_4677589_-\|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl\|CDD\|225921
NZ_CP025096.1\|WP_100989894.1\|4661168_4661396_+\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|225291
NZ_CP025096.1\|WP_100989905.1\|4681967_4682834_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
NZ_CP025096.1\|WP_100989896.1\|4662727_4664623_-\|heparinase-II/III-family-protein	unknown	unknown	gnl\|CDD\|377945
NZ_CP025096.1\|WP_100993956.1\|4661929_4662700_+\|DUF2490-domain-containing-protein	unknown	unknown	gnl\|CDD\|378471
NZ_CP025096.1\|WP_100989897.1\|4664796_4666494_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993957.1\|4667770_4668439_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238872
NZ_CP025096.1\|WP_100989895.1\|4661395_4661731_+\|DUF5615-family-PIN-like-protein	unknown	unknown	gnl\|CDD\|375906
NZ_CP025096.1\|WP_100993958.1\|4674819_4676358_-\|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|223587
NZ_CP025096.1\|WP_100989906.1\|4683035_4684019_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381304
NZ_CP025096.1\|WP_100989903.1\|4679001_4681254_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NZ_CP025096.1\|WP_100989909.1\|4686480_4687116_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100989904.1\|4681264_4681744_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	4.63435e-79
NZ_CP025096.1\|WP_100989899.1\|4669550_4672808_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	8.67513e-140
NZ_CP025096.1\|WP_100989902.1\|4677761_4678847_+\|gluconolactonase	gnl\|CDD\|308585	pfam03022, MRJP, Major royal jelly protein. Royal jelly is the food of queen bee larvae, and is responsible for the high reproductive ability of the queen. Major royal jelly proteins make up around 90% of larval jelly proteins. This family also the sequence-related yellow protein of drosophila which controls pigmentation of the adult cuticle and larval mouth parts.	1.1677e-14
NZ_CP025096.1\|WP_100989908.1\|4684306_4686409_+\|TonB-dependent-receptor-plug-domain-containing-protein	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.0159e-38
NZ_CP025096.1\|WP_100989893.1\|4658671_4661140_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|350795	cd18037, DEXSc_Pif1_like, DEAD-box helicase domain of Pif1. Pif1 and other members of this family are RecD-like helicases involved in maintaining genome stability through unwinding double-stranded DNAs (dsDNAs), DNA/RNA hybrids, and G quadruplex (G4) structures. The members of Pif1 helicase subfamily studied so far all appear to contribute to telomere maintenance. Pif1 is a member of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	4.19311e-48
NZ_CP025096.1\|WP_100989900.1\|4672847_4674530_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	3.0793e-10
NZ_CP025096.1\|WP_100989898.1\|4666522_4667677_-\|hypothetical-protein	gnl\|CDD\|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	5.16792e-12
NZ_CP025096.1\|WP_100989901.1\|4676539_4677589_-\|SMP-30/gluconolactonase/LRE-family-protein	gnl\|CDD\|225921	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism].	3.89796e-49
NZ_CP025096.1\|WP_100989894.1\|4661168_4661396_+\|DUF433-domain-containing-protein	gnl\|CDD\|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	2.62128e-24
NZ_CP025096.1\|WP_100989905.1\|4681967_4682834_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	8.89288e-14
NZ_CP025096.1\|WP_100989896.1\|4662727_4664623_-\|heparinase-II/III-family-protein	gnl\|CDD\|377945	pfam07940, Hepar_II_III, Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.	4.21295e-08
NZ_CP025096.1\|WP_100993956.1\|4661929_4662700_+\|DUF2490-domain-containing-protein	gnl\|CDD\|378471	pfam10677, DUF2490, Protein of unknown function (DUF2490). This is a bacterial family of uncharacterized proteins. They appear to belong to the outer membrane beta barrel superfamily.	1.05673e-38
NZ_CP025096.1\|WP_100993957.1\|4667770_4668439_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238872	cd01834, SGNH_hydrolase_like_2, SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.29163e-39
NZ_CP025096.1\|WP_100989895.1\|4661395_4661731_+\|DUF5615-family-PIN-like-protein	gnl\|CDD\|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	3.60292e-29
NZ_CP025096.1\|WP_100993958.1\|4674819_4676358_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	8.77513e-129
NZ_CP025096.1\|WP_100989906.1\|4683035_4684019_+\|aldo/keto-reductase	gnl\|CDD\|381304	cd19078, AKR_AKR13C1_2, AKR13C family of aldo-keto reductase (AKR). The AKR13C family includes Helicobacter pyroli aldehyde reductase (AKR13C1) and Thermotoga maritima aldo-keto reductase (AKR13C2). Aldehyde reductase (EC 1.1.1.21), also called aldose reductase, is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides.	0
NZ_CP025096.1\|WP_100989903.1\|4679001_4681254_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	1.12035e-65
NZ_CP025096.1\|WP_100989909.1\|4686480_4687116_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.03069e-38

>NZ_CP025096.1|WP_100989900.1|4672847_4674530_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKLINPNKFLSTALFATLMLAGVSCKEQLDVGNPNQPTVTANVNTETGLIAFAQGGVYINGFLNGDGWLGNSYFSLPIGYSELMADNVGADASNNQVTTIGVPDYIILDDGTKVTNPAPQVGIIRSYNTRAATGAGNNAIYYQWLNMYALNNVCNQTLDLVSTISFAGDATSRANTIKAWAYWWKGYAYASIGSMYYAGLIEDKTGVTNGDYVTHDAIINQSNTYFNLAATTLTAITSATDYTEVMTQLIPSFNQVGNGGVPTVDMWKRNINTMLARNILVNKLAPFVNGNPAATISKSSTTAMTAADWTSVLTLATNGIKNGDVVFTGRSTASNAFFSPSGGTVASLATGVNTSTTFKISERFIQSFNTGDKRLSNNFNTATTYKNNYTFTTRYSITANGNGTPGVYVYGSKDVGAYEVYMAGSYEENTLMLAEANMRLGNIDTGLGFVDAVRTYQGAGVAAVKGAGLTLAGALTELTKERRVSLFGRGLSFYDNRRWGWTYDISVGGGSYGNTIVTTAGVVNTKATINYNFMDYWDVPADETVLNPPTSSVATRNPNY
>NZ_CP025096.1|WP_100989899.1|4669550_4672808_+|SusC/RagA-family-TonB-linked-outer-membrane-protein
MRKFICMSMLLICALSITAWAQDRRIIGKVTSAEDGSSLPGVSVVLKGTSKGTTTDAGGIFDISVPSAKGITLVFSFVGVATQEVPVGNQSEVNVSLVSDSRLLTEVVVTGSGVATSKAKLGIAVESVSAKDLPQTPTASIDQALIGKIPGAQISSTSGNPGDPVNILLRGINSVQGGTKPLIMVDGVQIASTDINSLDLSNVDRVEVVQGAASASIYGAQGANGVIQVFTKKGKKGRTAVNFSSSYSANEFLNTGNVHKADLHPYLTDANNNIIDTQGNILDYTQYGAIEGISYKYGGATRYAIQDIRNDANTPYSGNLKYYDHFKQVFKTGSTTNNNINVSGASEKSDFNIAAANNHTSSPILTKENGYIDRSNLSANIGTELFKGFTIRSTTQLVYTKNTLKPGLGAAYGPFNGGNGNVGSVYNFLNTSPFFDLTRKLADGTYPVYPTADFLSVNAGNPYYQASYTDAINNKIDVLQNFNANYKINKFLELDAKYGINYRNETARWTYFNQSQNTSSEYYQSWTANYAPDNKGEIDNFQYNNTFQNFLGTAFIRTDFQDDFHIKLPIQTSTQISFDYRKNRSTQYDTYGVGLSTAPPFNVAATSSQAVANDIVTPFITYGYLVNQKVDFGDYGGITAGFRTDWSSAFGAGSTPFTFPHFDGHIAPLSFFKNSSLSNTLPYFKLRAAYGEAGIQPGAFDRYPVLSQRNLGSGLVYTVPTTTQNPNLKVEVSKELEIGTDFTIGGNSNRAWLSSLSGSFTYWKRSSANVIYTVSVPPSLGSTGQLTNAIDMSSNGVQFSLSLPIYRSKDLKWDFTTNFGHQVSKIDAISGGADIILTSNAGSTALVLTPGQPIGQVYGYKTLTSLDFKNQEGVPYITDANRGNYTMVGNYVVDKTTYQPQFTNETYPLMNPNPKFNASFINGVSFKNFVTLNFQFDWVYGSHLYNQTKEWMYRDGISGDFSKPVTIDGKTGAYTAYWSGAYYGLWGSTRGAGNNATKDFFVEDASFVRLRNISLAFDIAKVVKLPYLNKAQIVFTGRNLMTFTKYTGYDPEISSGTSNSSFDRGVDHSTLPNIKSYQVGLNIGF
>NZ_CP025096.1|WP_100993957.1|4667770_4668439_-|SGNH/GDSL-hydrolase-family-protein
MTTIIRSLLFLLTVGLLAMSAAKPTRVVFFGDSITQAGVGPGGYIDRLKKMLPSDQFELIGAGIGGNKIYDLFLRMDDDVLAKQPDVVIVWVGVNDVWHKASFGTGTDPDKFVKFYEALVKKLKAANARVMLCTPAAIGEKTDFSNQQDGDLNQYSQLIRDLAKRQNIPLIDLRKAFLEYNMKNNPENKEKGILTTDRVHLNEAGNILVAEQMQKALTEAVK
>NZ_CP025096.1|WP_100989898.1|4666522_4667677_-|hypothetical-protein
MKKSIVLALICGVFLVSTTGWISFSDSNESGFGKPAPKVQRYLYVVTPGVRNYLGYGGHGIQVFDIDNNHRFVKFIKTAGLSKNGKPSNVKGVDVSLATNCLYISTLEALQCIDLTTEKLLWERQYDGGVDRISISPDGKIIYMPSLEKEFWTVVDAKTGDVLKKIVTNSGAHNTIYGPDGNFVYLAGLKSTMLNVADTKTHSVTKQVGPFGADIRPFTINGAQTLVYVNVNGLLGFEVGDLVTGKFLHRVVVEGFNIGEVKRHNCPSHGIGLTPDEKELWVCDGANNRLHVFDNTVMPPVQKTSILLKDMPGWITFSLDGKYAYPSTGDVIDVKTRKISTSLEDQNFNDVQSEKMVEIHFSGGKAVAAGDQFGLGQVRKAGRN
>NZ_CP025096.1|WP_100989897.1|4664796_4666494_+|hypothetical-protein
MDRRQFVAKATTSLCLLPSLTLFENPAPAIKPPWLLELLKLNDQQLTTIRTTRITAPDNPALGGLKDGDDIPNPQSTADFIRRAACAIASPESQYYRSTELLEEVRMAVAYLLAVQHSDGTLDLPATNFHSTPDTGFIVKRLAPAYSLLADSKTPGLDSVLPTYKTFLLRAGEALTVGGIHTPNHRWVVSAALVRLHALWPDARYVARVEQWLSEHIDMDKDGQYNERSTLIYSPLTNRLLITIAKGLNKPYLLDYVRRNLLMTLYYIHPNGEVVSEASGRQDKALTGTMEGYWYAYRYMALHDKNGEMAEMSRNIEKTALAKAVYYLDYFLEDPSLWRELPDSKPLPTNYQKTFTNSGLVRIRRNNRDSTILSASPVFLTFHKGEAVLQGLRIAASFFGKGQFQTETIVQEGTSWILTQSLDGPYYQPYPTKAIPADGDWEKMPRANRKQSEVQHLKTRIILRETPGGMEAQIQMTGTTGVPVSMELIFRPGGTFAGVTKHPTRANAYLLSDSGTYTVKGDTITFRPGKALHKAVQLRGALPAMDAPTVYLTGFTPFEHTLKLS
>NZ_CP025096.1|WP_100989896.1|4662727_4664623_-|heparinase-II/III-family-protein
MVYLRSFAGILAVSLFFQLAIQAQSNQLNATAKLPDHPRLLLLKGEEETIKRTINADKTWAQLHQAILAECDAMLPSVPLERIQIGRRLLDKSREALRRVFYLSYAWRMTHQTKYLQRAEKELLAVSAFSDWNPSHFLDVAEMTMAVSIGYDWLYNDLSAPSRALIKAAILTKGIATSMDPKNNSWLTSSNNWNQVCNAGITYGAIAIYEDQPEASKALINRALQSVILPMGDYKPDGAYPEGYSYWGYGTSFNVLLISALDKLFGSDFGLSEQPGFLKSAGYLENMTGPSGKAFNYSDSGLGGELQPAMFWFAKKLNNPSLLWVERSRLMNSDVKKYVRDRILPAALLWSNGVKLDQMTEPTSLMWVGAGKTPVALMRSSWSDPSAIYVAMKGGSPSTNHAHMDAGSFVVEADGVRWAMDFGMQEYESLEAKGVDLWNMKQNSQRWQILRYNNFAHNTLTVNGQLQRVEGVAPLTGYASTPMFMNATADLTSLYKESVLKANRGVALINKAYVVVRDEIETLPAETTVRWTMLSPASAKLIGANKVELTKDGKTLTLQVMEPATVTMKTWPTDPIHEYDAPNPGTILVGFEVKLPASTKTAITVTLTPGSSAGQKQMVIQPIAQWPRHTD
>NZ_CP025096.1|WP_100993956.1|4661929_4662700_+|DUF2490-domain-containing-protein
MTFRYFLFLLLFSTTGFSQQNRVIDRNAIGWFTYNGDHKLNKRWELHTEYQWRRVELIQSWQQSLARLGLAFTLTDQVKLGGGYTFFTTYPYGDYPVADAGVPTIENRTQQDIQFSATAGIVKLSHRFRLEQRWLGSGADSNPRHIEGWEYQNRARYQIAGTIPLQGATIDDGEWYVNFFDELFIGFGRNVEQNVFNQNRISGGLGYQFRESFSIELNYLNQISQHPELEPITRKPVFEINNGFRLNVKYDLDFSK
>NZ_CP025096.1|WP_100989895.1|4661395_4661731_+|DUF5615-family-PIN-like-protein
MKLVLDANLSYRLVKKITSEFPDCVHITRTGLPIPAEDVAIWQWAKINSCIIVTNDDDYYNLANTYGFPPKVVLLRMGNQSSTGVMNTLLKHRDEIQQLDQSNEVGLLELF
>NZ_CP025096.1|WP_100989894.1|4661168_4661396_+|DUF433-domain-containing-protein
MSNYAEFIRLNPNIRFGKPCIIGTRIAVQDILGWLASGMSNVDILEDFPELSLEHILAALAFAADSERRTRLIAA
>NZ_CP025096.1|WP_100989893.1|4658671_4661140_+|helix-turn-helix-domain-containing-protein
MTVSVNEKLDLAHNFVLHTNQNIFLTGKAGTGKTTFLQQIKQLSAKRLVVVAPTGVAAINAGGVTIHSLFQLPFGPLTPGTTQREGKKFNKEKINLLRTLDLLVIDEISMVRSDVLDGIDEVLRRYRTSSAPFGGVQLLLIGDMQQLPPVIKDDDWALLKPYYETGYFFGSKALRQTSYVPIELTHIYRQTDERFISLLNSIREKTVTRAQLDNLNQRYIPDFSPGDDEGYITLATHNTAAQQINIQKLLALKGKPRTFTATVEGDFPAHTYPTDASLELKVGAQVMFIKNDISRDKLYYNGKIGRITDMDDSAIYVKSQQDGEDIVVYPVDWTNIKYTLDPATKEIKSEPIGTFRQMPLKLAWAITVHKSQGLTFEKAILDVSSAFAHGQVYVALSRCKTLDGLVLRSPIPAHSIKSELELEDFHQQVQLQTPNEQHLHQAKLTNQQHLLRELFSFERANSLLYRCRRVINEHASSLDAESSPILTQLTTSLREKASDVSGRFQQQLPSYFASDNLPEHNPALQDRVRKAGTYFKSLIGTELLPLLHSFPTDCDNKKVRDLLLETLDELEKELFSKQRSFESCQDGFNALSYLQARNRAELDFQPERKKHEPKAAEPTPSDGSARGGLYGALMKWRNDMAGEHNTSGFMVLPQKTIVELARVRPTNEAELLAVKGFGKTKVRQIGAEILRIVQENPSGRAASAGAPKTKVAKAPKEPKELSPAITLAFFQSGKTIAEIATERSLAVSTVESHLVRYVGTGELAVEALLPAQKLASIRAYIETYPSETLNQVRQSLGNDVSFSEIRFVQYALRAEAGGGGEE
>NZ_CP025096.1|WP_100993958.1|4674819_4676358_-|DEAD/DEAH-box-helicase
MNYLKATPVQEMAIPVILAGKDLIASAQTGTGKTAAYLIPLLDKISHTDHDHTSTLILVPTRELAKQIDEQVEGFGYFVQANSIAIYGGGKGDDWDKQRKALETGADIIIATPGRLIAHMQLGYVKFDKIDYLVLDEADKMLDMGFSDDIMNIVEKIPVKRQTLLFSATMPNKIREFSKKLLTEPEEIRLAVSKPAAGIDQQFYLAFDNQKLPLLAHLIKNSTKPVQSMVLFTSRKSEVNSIVRALSKLGYDSRGISSDLEQDDREVVLRDFKNKVFPILVATDVLSRGIDIDNLTHVVNYDIPRDAEDYVHRIGRTARAATTGTAITFISDQDQNRIVNIEKLIEREVDKQSITEELGMGKSPVFDPKRFSGLRGKGGSRGSGGSGRSGRDGGGRGDGGRGNGSRGDGRHSDGKRGDSPRGDNRGQRRDGQTAPAPVERLPSTEAKNGSLETPVNGASETLAQVRPAVDGQLSDKPKRRKKRRRGPKGEVPGDAASQPKQQADSVPVSDEK
>NZ_CP025096.1|WP_100989901.1|4676539_4677589_-|SMP-30/gluconolactonase/LRE-family-protein
MYQRIAFKTLCLGWFLSGAALAQTEQTYATIGEVVRNDAKLNQLIPPDAKIEIIAAGFGHLEGPVWVKSRVADSSGYLLVNDTKAQTTYKWSPQTGLSKYIEHTGYTGHLPYSEEPGSNGMTIDRQGRLIVCDHGDRRIAALPLAGKGGKRTLTDAYQGKRYNSPNDVVAHPNGSLYFTDPPYGLPLKDKDPTRETTVNGVYRLEPNGTVTLLIRDITYPNGLSFSPGKGNLLYVVQSDSLNQKIMTYPVKDDGTVEKGRLFFDASTLPKFRPKEVIDGIKVDSEGNCWVAGPGGVLVISPASKLLGRIDTGEVISNLAWGDDGTTLYLASSMFLCRIKTNVKGILAGK
>NZ_CP025096.1|WP_100989902.1|4677761_4678847_+|gluconolactonase
MKIAYLIGFMTLTNLSLNAQSGQSPDLETVAEFGKHQPIGVGVSQEKRIFITFPKNRENYDYGLAEIVAGKRVPYPNAEWNKWDSLNPQNRFINVQALFVDQTNALWVLDPANPADEPPISAGIKLMKINLATNQVETIYRFDDLPRERTGLNDIQVDTRRQVAYLSDPKRSAIVVLDLKTGKSRTVLEGDKSTKADPEFKLKIDGQEVKDDKGKPFSSNVNGIALTRDFTYLYFRAINQTRLYRIATEFLNNLALSPAEVSSHVETMAETGVSHGMVADKAGNVYLTDSPTKAVRYLTPGRELKTLVRDSRLLWPDSFAVGTDGYLYLTAAQIHRTKRYNNGQDKVDYPFRLYRMKLPNQ
>NZ_CP025096.1|WP_100989903.1|4679001_4681254_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MTTNKSTYNRRSFLKASLLSGGGMMLSVSWLSRVKAADKLQTLNLPEQWTELNGYIQITANNVVKLICPNPEFGQNVMTSLPMMVAEELDAEWKNVVVDMGPHDNAKLGPQFTGGSNSVRMYWKPLREAGAAARQMLCEAAAQSWGVSVAEVTTKAGMLHHASGKSAKYGEMASKAATLPVPKGVKLKAPKEFTIVRKPTRNVEGKKIVTGKPLFGLDYRTEGMLIAMIQHPPAFGMKLKSFDASQTLKMPGIKDVFTLKLYEDGFEQGGFDTRTFNELLVVVGKSTWEVMNARKKLKVDWEPAGDTKDTMAGRDGKRAVIVPGELESTSAQLEKFQEYAKKPAQLLRKDGDPETAFKNAAQIIERTYNAPFLAHNTMEPMNFFAHVTDEKALLVGPLQAPGWVEPTLSKILKLPADKIEIQMTRMGGGFGRRAYAHYMSEAALISRKVKAPIKLIYTREDDMTYGIYRPMYTATYRAALDANKNLIGFHVKGGGIPEHAIHANRFPAGAVDNYLAEGWEIPSNITIGAFRAPRSNFNAAAEQSFLDEVAEAMGKDPIEFRLELLKRAKENPVGKNNEYDADRYAGVLTLVRDKSGWNKPNNEKYHRGVAAYFCHNSYAAHVVDMVTRDGGPYVERVFSAMDCGIVVNPESATNMVQGAVVDGIGNAFYGALTHKNGAAEQSNFNNYRLIRHNEAPKKIEVHFVENDLDPTGLGEPPFPPVFGAVANALYKTNGKRQYNQPFNSQLDKRI
>NZ_CP025096.1|WP_100989904.1|4681264_4681744_-|(2Fe-2S)-binding-protein
MAKYSLKINGKIRQLDVDPSTPMLWVLRDHLDMPGTKYGCGIAQCGACTVHLNGTAVRSCQLPISAVGKEAITTIEGLSATGEHLVQKAWLEHDVAQCGYCQSGQIMSAASLLKTNPKPTDEDIDLAMSGNICRCGTYLRIKEAIKSAAKEGVASSTRK
>NZ_CP025096.1|WP_100989905.1|4681967_4682834_-|AraC-family-transcriptional-regulator
MDTLLRFETINDYNVFNNNETLHPLVSVVDLSKAAPRQGSRMYFGFYAIFLKDVNCGDLVYGRHTYDYQEGTLVFMAPGQVVGVNNNGETYLPKGYALVFHPDLIHGTSLGRHIQEYTFFGYQSYEALHLSNRERQIVLDCFSKIEYELEHAIDKHSKKLIVATLELFLGYCTRFYDRQFITRENVHKSALERFETLLNDYFLTDKPQAIGLPTVTYCAGELNLSANYFGDLVKKATGKTAQEYIQAKVIDLAKERIFDQSKSVSQIAYDLGFKYPQHFMRLFKQRVG
>NZ_CP025096.1|WP_100989906.1|4683035_4684019_+|aldo/keto-reductase
METRTLGKSGLQVSALGLGCMGLSYGYDPATDKQDAIQLLRAAFDKGVTFFDTAEAYGPFANEELLGEALQPFRNEIVIATKFGFVNGDSTKGLDSRPERIRQVAEEALKRLRTDRIDLFYQHRVDPNVPMEDVAGTVKELILEGKVKHFGLSEAGAASIRKAHAVQPVAALQSEYSLWWREPEKEILPTLKELGIGFVPFSPLGKGFLTGKIDENTQFDKTDFRNVVPRFSEENRKANQKLVDLLGDIARQKEDTPAQIALAWLLAQKPWIVPIPGTTKLHRLEENVGAAAITLSADDINQIDTAFAAIPVQGDRYPAHLLKRVGN
>NZ_CP025096.1|WP_100989908.1|4684306_4686409_+|TonB-dependent-receptor-plug-domain-containing-protein
MLNRLLPTVLFLGFLSPAILFAQTSTPSLEDTLQLNEVVVRGYATNRRLLETPASVGLLTRRDLNQRFGTPTLVPALNTLPGVRADERSPGSYRLAIRGSAIRSPFGVRNIKTYWNELPLTDAGGNTPLNALDVRALGRIEVIKGPSGSLYGAGTGGTILFSGLGVPAGKTSVEVSALGGSYGLYGNGIAIQTGKNNSAISLNYNHLQSDGYRDQSAVVRDNLSLIGSFSVSPKRTISVLALYSDLHYQTPGGLNEAQFKANPRASRLATATLPSSAAQQAGIYQKVGYLGFSHEYRWNDRIQNTTVIYGSTTDFANPFITNYEKRADQGLGGRTITQIRFPNGPLPTVVTVGAEYLRNFTVDRNFGNRGGTADTIQTDEELTARQSTVFLQTETELPAHFRLTAGLSRNDVRYGFTRFPTRAAGALPATLLARDFAPVWLPRVALLRTFGQNVSAFVSISTGYSAPSSQEVRPSAGGFNTTLNPERGTSYEVGVRGSALHSRLRFDVAVYQFQLRETIVRRSDAAGAEFFVNAGRTDQRGLEAQFSYDFVLPSSRSTVSLLRLWNSLTLTNYRFRDYLQGTVDLSNNKVPGVAPTTNVTGIDAETNVGLYAHVTYSFLKEFPLNDANTFLSDPTQLLQATLGFRHALGKNWAIDVYASGDNLLNRTYSLGYDLNAVGNRYFNAAPARNGVGGVRLSVKW
>NZ_CP025096.1|WP_100989909.1|4686480_4687116_+|ABC-transporter-ATP-binding-protein
MLTVSSLTKAYNGHVVLTVPEMHLSPGIHYFQGGNGSGKTTFFRTVGGLLPFSGTILLEDQFEINRDPVAYRFRVNYAEAEPLYPSFLTARDLAGFVGKAKKAPAGQVQKLAELLGVDTFWTQPTGQFSSGMLKKLSLLLAFLGTPRLLLLDEPLTTLDVATAARLFDYIRQLRAEQDVSFLLTSHQDISLTGLPLTAMWQVGNGLITPAT
>NZ_CP025096.1|WP_100989910.1|4687124_4688201_+|hypothetical-protein
MLTLLNRIFVSSFYTKNAGTFLVIILLAFGFLSAVEHKALITAALGSPLVLAIVFGLWGLYLLKTVSFIWQELTAPEHLFFQTFWLIPTPTRLLLWVAVQTAMLLPILAYAQWMIQIAYQYQRWDSLSAIVIINLLYIGIGSLAADYRLRHPNPNAWHLPHVSLKLPYEFFFPTYWLRQEPLSLVLTKVFSGLLLAGVCRLYPTDDYDQRLLLIGLLLAILGHAQVGGQVSAFEQKYLLSLPNLPMSRIQRFGRYALMYGFLWLPELVILLHNCPVGIPLDYIIWLWLTGLGALLLLHSLAYGHEINPERWLSGVFASFIGGLLAIMFGLPVGAWLVLVWTGALGYWSWSFALREMTP

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Crispr_ID: NZ_CP025096_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_4

6008500-6008587

Orphan

Consensus_repeat	Method
ATGTCGGAACCGCCCCCGGCTTGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025096_4

>merge|NZ_CP025096|4|6008500-6008587|CRISPRCasFinder
ATGTCGGAACCGCCCCCGGCTTGCAGGTTCAGGTCGTCAAATGTTAGCATACCCTGGCCAAAAATGTCGGAGCCGCCCCCGGCTTGCA

>NZ_CP025096|4|4|6008500-6008587|CRISPRCasFinder
ATGTCGGAACCGCCCCCGGCTTGCA	GGTTCAGGTCGTCAAATGTTAGCATACCCTGGCCAAAA
ATGTCGGAGCCGCCCCCGGCTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100991079.1\|6004528_6004897_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|227786
NZ_CP025096.1\|WP_100991101.1\|6015284_6015872_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP025096.1\|WP_100991105.1\|6017065_6017347_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100994045.1\|6006965_6008102_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP025096.1\|WP_100991083.1\|6005268_6005961_-\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|224299
NZ_CP025096.1\|WP_100991103.1\|6015939_6016953_+\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379142
NZ_CP025096.1\|WP_100991085.1\|6006048_6006885_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|226479
NZ_CP025096.1\|WP_100991075.1\|6001810_6003571_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_CP025096.1\|WP_100991097.1\|6013840_6014845_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223318
NZ_CP025096.1\|WP_100991095.1\|6012344_6013760_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP025096.1\|WP_100991099.1\|6014935_6015178_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100991069.1\|5999194_5999617_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100991093.1\|6010760_6012251_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP025096.1\|WP_100991077.1\|6003745_6004477_+\|LPS-export-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213185
NZ_CP025096.1\|WP_100991091.1\|6009845_6010679_-\|aminotransferase-class-IV	unknown	unknown	gnl\|CDD\|376449
NZ_CP025096.1\|WP_100991073.1\|6001335_6001770_-\|DUF2141-domain-containing-protein	unknown	unknown	gnl\|CDD\|378303
NZ_CP025096.1\|WP_100991089.1\|6009182_6009866_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP025096.1\|WP_100991107.1\|6017495_6017744_+\|MoaD/ThiS-family-protein	unknown	unknown	gnl\|CDD\|340452
NZ_CP025096.1\|WP_100991071.1\|5999713_6001186_-\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|376340
NZ_CP025096.1\|WP_100991081.1\|6004909_6005206_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	unknown	unknown	gnl\|CDD\|378301

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100991079.1\|6004528_6004897_-\|transcriptional-regulator	gnl\|CDD\|227786	COG5499, COG5499, Predicted transcription regulator containing HTH domain [Transcription].	6.49475e-32
NZ_CP025096.1\|WP_100991101.1\|6015284_6015872_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	8.6974e-20
NZ_CP025096.1\|WP_100994045.1\|6006965_6008102_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	3.70711e-136
NZ_CP025096.1\|WP_100991083.1\|6005268_6005961_-\|DNA-repair-protein-RecO	gnl\|CDD\|224299	COG1381, RecO, Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair].	1.12397e-18
NZ_CP025096.1\|WP_100991103.1\|6015939_6016953_+\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	4.65366e-30
NZ_CP025096.1\|WP_100991085.1\|6006048_6006885_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|226479	COG3970, COG3970, Fumarylacetoacetate (FAA) hydrolase family protein [General function prediction only].	1.91132e-48
NZ_CP025096.1\|WP_100991075.1\|6001810_6003571_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	1.45463e-173
NZ_CP025096.1\|WP_100991097.1\|6013840_6014845_+\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|223318	COG0240, GpsA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	8.75715e-92
NZ_CP025096.1\|WP_100991095.1\|6012344_6013760_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.09697e-44
NZ_CP025096.1\|WP_100991093.1\|6010760_6012251_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	7.83339e-32
NZ_CP025096.1\|WP_100991077.1\|6003745_6004477_+\|LPS-export-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213185	cd03218, ABC_YhbG, ATP-binding cassette component of YhbG transport system. The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.	1.88601e-148
NZ_CP025096.1\|WP_100991091.1\|6009845_6010679_-\|aminotransferase-class-IV	gnl\|CDD\|376449	pfam01063, Aminotran_4, Amino-transferase class IV. The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.	3.75744e-46
NZ_CP025096.1\|WP_100991073.1\|6001335_6001770_-\|DUF2141-domain-containing-protein	gnl\|CDD\|378303	pfam09912, DUF2141, Uncharacterized protein conserved in bacteria (DUF2141). This domain, found in various hypothetical prokaryotic proteins, has no known function.	5.18803e-37
NZ_CP025096.1\|WP_100991089.1\|6009182_6009866_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	6.29254e-106
NZ_CP025096.1\|WP_100991107.1\|6017495_6017744_+\|MoaD/ThiS-family-protein	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.25646e-23
NZ_CP025096.1\|WP_100991071.1\|5999713_6001186_-\|IMP-dehydrogenase	gnl\|CDD\|376340	pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain. This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains pfam00571 are inserted in the TIM barrel. This family is a member of the common phosphate binding site TIM barrel family.	0
NZ_CP025096.1\|WP_100991081.1\|6004909_6005206_-\|type-II-toxin-antitoxin-system-HigB-family-toxin	gnl\|CDD\|378301	pfam09907, HigB_toxin, HigB_toxin, RelE-like toxic component of a toxin-antitoxin system. HigB_toxin is a family of RelE-like prokaryotic proteins that function as mRNA interferases. HigB cleaves translated mRNA only, and cleavage depended on translation of the target RNAs. HigB belongs to the RelE super-family of RNases. The toxin-antitoxin gene-pair is induced by environmental stress factors.	5.31178e-36

>NZ_CP025096.1|WP_100994045.1|6006965_6008102_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MTPTIGILGGGQLGLMLLQASIDWNLRVHILDADAEAPCRHLCTKFTQGSLTDYDTVYQFGQAVDVLTIEIERVNVEALEALEREGKKVFPQPSVIRIIQDKRLQKQFYLDNNLPTADFILTENRADVALLEIHQPDFLPAFHKLGRDGYDGRGVQRIASVADVGKAFDAPGVLEKAVDFEKELAVIVARNERGEMQTFPTVEMVFHPELNLVEYLFAPAEISEAVNQQAQDIARRTTEAFGIVGLLAVELFLDKQGNVLINEVAPRPHNSGHQTMRANVTSQFEQHWRAILNYPLGDTTAYQPAAMVNLLGEDGHTGPAVYEGLQELLAMPGVFPFFYGKAITKPFRKMGHVTVMDDSLEALREKVAVVQRGIRVIA
>NZ_CP025096.1|WP_100991085.1|6006048_6006885_+|fumarylacetoacetate-hydrolase-family-protein
MKLYKTRFGIVVDYQNQFYSVPDADWDELVNRDDLHDFLITLTALATPSDEYQSWTETGSLAPIGRQEVWASGVTYLRSRNARMEESKKSGGDNFYDRVYDADRPELFFKSTPERVVGPGANVRIRADSTWNVPEPELTLFITSSGKIVAYTCGNDMSSRSIEGENPLYLPQAKTYDGSAALGPCLYVPETPIAPETQIKLEIIRDKQAVFTNSIAINQMKRQHTELVEFLYRECSFTYGCFLMTGTGIVPPDNFTLQAGDEVRITIEGIGTLENVVS
>NZ_CP025096.1|WP_100991083.1|6005268_6005961_-|DNA-repair-protein-RecO
MLQKTRGIALSYIRYRETSIIARVYTEEFGLQSYVVNSVRTAKSKNNRIALFQPLTLLDMVVYHKPDRDLTRLSEVKTSCPFQSLPFDVGKSTIAMFVTEMLNKVLKEEASSPVLFRFLAESILFLEEATINYENFHLIFLLKLSFFLGFGPENAREFESQLRENAYPFLPDDEMDTALNSMLRLPFGTPIKLSRSARNELADALVTYYHIHIDSLGEVKSLPVLREVFG
>NZ_CP025096.1|WP_100991081.1|6004909_6005206_-|type-II-toxin-antitoxin-system-HigB-family-toxin
MKRIIAKRTLKEFWEKHSDAEQYLKTWYETAKQAEWKSPNDVKKTYANASIIAGNRVVFNIKGNDYRLIVKFNYQQQWAFIRFIGTHSLYDRVDATTV
>NZ_CP025096.1|WP_100991079.1|6004528_6004897_-|transcriptional-regulator
MIIRPLKNEADYDLALERLNEIFDASANTPEGDEAELLILLIDSYENEHYAIEAPDPIEAIKIRLEEMELKQQDLVGIIGGKSRVSEVLNRKRKLTVDMIRKLTEALHLSAATLIGEYQLVK
>NZ_CP025096.1|WP_100991077.1|6003745_6004477_+|LPS-export-ABC-transporter-ATP-binding-protein
MILRTENLVKKYGSRLVNDNVSYQVETGEIVGLLGPNGAGKTTSFYMAVGLVKPNSGKVFIDDKDVTDLPMYKRARLGLGYLAQEASVFRDLTVEENVLAVLEMSSLPKKDQKQKVEELLEEFSLTHVRKSKGKVLSGGERRRTEIARALAVDPKFILLDEPFAGVDPIAVEDIQSIVAKLKHRNIGILITDHNVNETLSITDRAYLLFEGKILKQGTAEELANDEQVRRVYLGQHFELKRKV
>NZ_CP025096.1|WP_100991075.1|6001810_6003571_+|single-stranded-DNA-specific-exonuclease-RecJ
MIAQPPPPSKRWITRSFPNSKEQQGAIETLTNSLGVSPFLSALLVQRGVQTYEEARTFFRPEIGHLHNPFEMKDMNKAITRLQMAMLPERQEKILIYGDYDVDGTTSVALVYSFLKNYHTAIDFYIPDRYKEGYGISSQGIQWAADNGFSLIIALDCGIKSIERVAEAKALGVDFIICDHHRPGDIVPDAAAVLDPKQEDCLYPYKELSGCGVGFKLMHAFCLHKSIPLDELYPLLDLVAVSIASDIVPITGENRVLAYYGLKQINASPRTGLKALIKIAGFSLGRELDITNLVFGLGPRINAAGRIQHAKAAVQLLLAESEEEADEFAMAINKHNNSRREFDSSITDQALAMIRENESLIHAKSTVLYDATWHKGVIGIVASRCIEHFHRPTIILTQSNDKAAGSARSVPGFDVYEAIEECADLLEQFGGHTFAAGMTMAVSNIEAFQKKFEEVVARSIKEEHLTPLIDIDLPLDFSEINDKLYRIVRQMGPFGPHNLQPTFMTEDVYLVSEPIIMKEKHLKLNVRQVDKASGRASQTLTAIGFGFAHIADQLRSGKPFSICYQVEQNHYNGNTTLQLMLKDVKV
>NZ_CP025096.1|WP_100991073.1|6001335_6001770_-|DUF2141-domain-containing-protein
MLYLLSIFSFFLANVPNPDAPKKTNLTVEVHNVRVFTGAVYVAIFKPGKDFPEGKPIEGKKVDASHERVQIAFSVEPGEYAIAVYHDENSNGKMDKRIFGIPKEPFGFSNDFRPKLSAPKFSDCEVKVGDSGKTVRIKLEKMSG
>NZ_CP025096.1|WP_100991071.1|5999713_6001186_-|IMP-dehydrogenase
MSLDTSKFLYEALTYDDVLLLPAYSEVLPRDTKTVTQLTRNIQLNIPLISAAMDTVTESALAIAMAQEGGIGIIHKNMSIEAQADQVRKVKRSESGMIIDPITLLETATLADALKIMREFKIGGIPVVDENNKLVGILTNRDLRFQNDTSLPVTGIMTQKNLITAREGLTLEEAESILQQYRIEKLPIVNNDYQLVGLITYKDILKKKSHPNACKDELGRLRVGAAVGVTPDLIQRIEALVKAGVDVISVDTAHGHSKGVLDAVRTIKEKFPKLQVMAGNVATGEGAKALADAGADAVKVGVGPGSICTTRIIAGIGMPQLTAVYEAANALQGTGVPIVADGGIRFSGDITKALAGGASTVMIGSLLAGTEEAPGEVVLYEGRRFKTYRGMGSVEAMEEGSKDRYFQDAEDDIKKLVPEGIVGRVPIKGRLSEIVYQMVGGLKAGMGYCGAIDIPTLQQAKFVKITSAGVRESHPHDISIQKEAPNYSAR
>NZ_CP025096.1|WP_100991069.1|5999194_5999617_+|hypothetical-protein
MVTPHTTLCPSATAQEGALLLGVVGPDKSVRFLPEPEPMTTQLTESVTAIDNPEQHFRFANKCAKSGCNQWQSGRCGVIDLVMSVNQHLEAPVSLPPCAIRAQCRWHKQSGPTACTVCLFIITDSSKTSEERLEYIDANF
>NZ_CP025096.1|WP_100991089.1|6009182_6009866_+|ABC-transporter-ATP-binding-protein
MIQLNNVSKYYPAGFGRVYVLRNITLDIAQGEFVSIMGPSGSGKSTLLHILGLLEEPSEGEYLLDDHPVQKLSEKRRTELHRTQIGFVFQAYHLIDELTVYENIETPLLYKGLSGSERKSRVAELLDRFNIVARKDLFPAQLSGGQQQLVGIARALAAHPSVIFADEPTGNLHSDQARDIMEIFRELNQKDGVTIVQVTHSEVNAEYGSRIIRLKDGWLEPSVQNVI
>NZ_CP025096.1|WP_100991091.1|6009845_6010679_-|aminotransferase-class-IV
MFLVYNSDILPEDDFRLSVNDRAFQYGDGLFETIRYETNQIWFWSDHFDRLSAGMSAIQFTPPDNFTAETVHAAILQLLSTNKLLNQPARIKIQVWRQLGGLYTPTTNKANVLITARPGNSFSITEKAKTEIYDAFRLSPSPISAFKTLNSLPYVLAGLHKNQSFLDDVILLDTEGNVAECLASNLFWFANEALYTPSLQTGCINGIVRRQLIRLAPTQGITLCEGLYKPDVLARAEAIFCANVMGVQWLNEVNKNVVRPAEEAKQQLNGLLNHILD
>NZ_CP025096.1|WP_100991093.1|6010760_6012251_+|TolC-family-protein
MQVAWKQMRVVAALILTANLSATYAQTTAVVSPGNGASASNRLNLQQCIDVAQQNNIQIRQGQLTVANSNLQLHQSRLNLLPTTNFQANQGLNGGRSINPQSNGFVQQSIVSGNYQLNASATVYNGMTLRNTIKQNDLILQASEQELSATKNNVSLTVAQNYLNVLIGTEQLAVAQRQADVTRAQLDRTQKLVNAGSAPEANLFELRATLASNEVDIITAQNTLDLAKVSLLQAMNVPINQDFEVEQISVPDPGLDPYTASVQQLFDVASGNLPEVKGADLRVKSAALGVQVAKGALYPVLTLNGNLSSLYSSAANQQNIPNGTTRQQISGFFTDANGSPVPVYTNISGSDIVNVTYFDQLQNNFNRSASLFLRVPIFQGNLSRNRITTAKIQQQNAELTAQNTRLTLRQQIETAYTSMRAAANKFKATQVQVASLEKAFQVAESRLNAGAINATDYSIAKTNLDRARNSLVQTKYDYVFRTKILDYYQNKPLSFN
>NZ_CP025096.1|WP_100991095.1|6012344_6013760_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKKSNRIWWILGGLVVLLVGGLVAAKQAGMLGKPKSTEVDFASVKRLDITERVSASGRVQPQVEVKISPDVSGEIIGLYVNEGDPVKAGQLLCRIRPDNYESLLARARAAVNQSRAQLEQSKASVAQSNARLIRAKADYERNRKLFADKVVSSADLETSEANYNVAKQEVEAANANVNASKFNIQSAEASLRDANENLRKTTIYCPVNGTVSKLNIELGERVVGTSQMAGTEIMRIANLQNMEVRVNVNENDIVRVNLGDTADIEVDSYTTAGRKFKGVVYEIANTANGLTSSSGAAASLSADAVTEFEIKVKILNSSYADLLAIKDKKGYPFKPGMTASVEIITDRKAGVLAVPIAAVTTRAADSSAIDTGKAKEISNGTVNEQPADVAEKKDKPKEIVFVNVGGKATQREVKTGISDFENIEILSGLKPGEQIISGPFIAVSKKLKNGELVVKRDPNKVKKKDEEKEE
>NZ_CP025096.1|WP_100991097.1|6013840_6014845_+|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MKVNQPIRLTMVGGGSWATALVKILSENNVSVKWWLRKKSDADQIKKFGHNPSYLSDVQINTRKVKVCTKIRDSFKDSDYIILAVPAAFVSDALIGLKPADFGGKSVVSAIKGMIPGANQLVTDWVSEQYQVPVERMAVIAGPCHAEEVALEKHSYLTIASQSPDCAKDVADLLRCRFVQTTPVDDIYGIEYSAVMKNIIALACGITRGLGYGDNFQAVLVSNAMQEIKRFVDAIYPKHRDLSGSAYLGDLLVTAYSPFSRNRTFGTLIGRGYTIQSAQAEMNMIAEGYYAVKSIYEVNSRFNVNMPITNAVYNILYDRAAPTGEMNLLKELLM
>NZ_CP025096.1|WP_100991099.1|6014935_6015178_+|hypothetical-protein
MCLSKNYFALSADIVEAESVAIVESVAIVEAESAVVVVVVSVVSVFFELQDVARAIIAMKKKADFVIAFIFLGMFLFSDK
>NZ_CP025096.1|WP_100991101.1|6015284_6015872_+|sigma-70-family-RNA-polymerase-sigma-factor
MKESRSPILTDEELLMGLADGSDDALTQLYRRYFPMVLHFVTSNSGNEDDAKDIYQEALIVLYEKVRSGSLELHCQLKTYLYSVGRRLWLKQLAQRSRYMVRDVEMPATDEFVAGQIDDDLTDHEERDRQFDLMAESLTRLGEPCRTLLDDFYIQHLSMQDITEKFGYTNADNAKTQKYKCLMRLKRLFFSEYKA
>NZ_CP025096.1|WP_100991103.1|6015939_6016953_+|trypsin-like-peptidase-domain-containing-protein
METNEEKNIENALQAYGERIRFKQQLEAVQARTDMTVMRHDAETYRSEPAAQVRSLWHMYRTTLAVAASAAIITTFGSIFLYRSYQQSHQQEQQYSQLSKEIQAVKSSQRKLLNDYNGRGRGLSNNPAQVAGSGFLLTGDGYLVTNNHIVRDADSVYVQSTKGEVYKARVVYTDKAHDLAFLQLCDDSAFRSMPPVPYSFDARPSDLGERVYTLGYPREEIVYGEGYLSSGTGYRGDSTAYQVAIGVNPGNSGGPLLDEKGNVIGIISGKQTTSEGVSFAVKTNYLLEALNNIPADSLKGQPLRLNRKNVLANLSRKQQIKRMQEYVYQVKVFKHKD
>NZ_CP025096.1|WP_100991105.1|6017065_6017347_+|hypothetical-protein
MKKLMMLATAFLFSVAIVSAQDTKQNAKETAHQAKETTKAAGRKVGREADKAGDKISDAAKNTKEDVKDGTNKALNKADRKMKKAERKIDNSK
>NZ_CP025096.1|WP_100991107.1|6017495_6017744_+|MoaD/ThiS-family-protein
MDSSVSVLLFGITRDLTGQSTVSVPLSEGASVGDLLSQLHQNYPPLAEIRSLLIAVNGEYAEPEQLLAHHDEIALIPPVSGG

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Crispr_ID: NZ_CP025096_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_5

6827214-6827434

Orphan

Consensus_repeat	Method
TATGCCGATTTTAAATACACGAA	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP025096_5

>merge|NZ_CP025096|5|6827214-6827434|CRISPRCasFinder
TATGCCGATTTTAAATACACGAAGTTCGATGAATCGTCGTCCTTTCAGAAAGCAGCTTTTGAGCAGTATGCCGATTTCAAATACACGAAATACGACGAACGGGTTGATTTCGGTCAGGCTCGCTTTAACCGCAACGCCGACTTTAAATACACCCATTTTCCCCGTGGTACAAATTTCGACGATACCCGTTTCGAAGGCTCTACCGACTTCAAATACACCAC

>NZ_CP025096|5|5|6827214-6827434|CRISPRCasFinder
TATGCCGATTTTAAATACACGAA	GTTCGATGAATCGTCGTCCTTTCAGAAAGCAGCTTTTGAGCAG
TATGCCGATTTCAAATACACGAA	ATACGACGAACGGGTTGATTTCGGTCAGGCTCGCTTTAACCGC
AACGCCGACTTTAAATACACCCA	TTTTCCCCGTGGTACAAATTTCGACGATACCCGTTTCGAAGGC
TCTACCGACTTCAAATACACCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100992040.1\|6829713_6830316_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP025096.1\|WP_100992029.1\|6822072_6823068_-\|GHMP-kinase	unknown	unknown	gnl\|CDD\|224493
NZ_CP025096.1\|WP_100992033.1\|6824633_6825287_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992042.1\|6830924_6831593_+\|porin-family-protein	unknown	unknown	gnl\|CDD\|379226
NZ_CP025096.1\|WP_100992034.1\|6825323_6826112_+\|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl\|CDD\|378917
NZ_CP025096.1\|WP_100992043.1\|6834703_6835171_+\|damage-inducible-protein-DinB	unknown	unknown	gnl\|CDD\|225200
NZ_CP025096.1\|WP_100992037.1\|6827586_6828780_+\|DUF748-domain-containing-protein	unknown	unknown	gnl\|CDD\|377502
NZ_CP025096.1\|WP_100992027.1\|6818145_6821034_+\|DUF11-domain-containing-protein	unknown	unknown	gnl\|CDD\|377084
NZ_CP025096.1\|WP_100992026.1\|6816326_6817853_-\|sulfatase	unknown	unknown	gnl\|CDD\|293751
NZ_CP025096.1\|WP_100992041.1\|6830369_6830786_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992035.1\|6826229_6826577_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992044.1\|6836153_6836915_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|237252
NZ_CP025096.1\|WP_100994097.1\|6831695_6834707_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|366376
NZ_CP025096.1\|WP_100992030.1\|6823242_6823725_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100994098.1\|6835567_6836038_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992025.1\|6814383_6816168_+\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP025096.1\|WP_100992028.1\|6821119_6821983_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP025096.1\|WP_100992038.1\|6828896_6829223_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992032.1\|6823936_6824311_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP025096.1\|WP_100992039.1\|6829252_6829528_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100992040.1\|6829713_6830316_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.25761e-29
NZ_CP025096.1\|WP_100992029.1\|6822072_6823068_-\|GHMP-kinase	gnl\|CDD\|224493	COG1577, ERG12, Mevalonate kinase [Lipid metabolism].	2.26236e-19
NZ_CP025096.1\|WP_100992043.1\|6834703_6835171_+\|damage-inducible-protein-DinB	gnl\|CDD\|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	2.33793e-10
NZ_CP025096.1\|WP_100992028.1\|6821119_6821983_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	1.62387e-161
NZ_CP025096.1\|WP_100992034.1\|6825323_6826112_+\|PD-(D/E)XK-nuclease-family-protein	gnl\|CDD\|378917	pfam12684, DUF3799, PDDEXK-like domain of unknown function (DUF3799). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 265 and 420 amino acids in length. It appears that these proteins are distantly related to the PDDEXK superfamily and so these domains are likely to be nucleases. This family has a C-terminal cysteine cluster similar to that found in pfam01930.	8.36415e-15
NZ_CP025096.1\|WP_100992037.1\|6827586_6828780_+\|DUF748-domain-containing-protein	gnl\|CDD\|377502	pfam05359, DUF748, Domain of Unknown Function (DUF748).	7.46837e-11
NZ_CP025096.1\|WP_100992027.1\|6818145_6821034_+\|DUF11-domain-containing-protein	gnl\|CDD\|377084	pfam03629, SASA, Carbohydrate esterase, sialic acid-specific acetylesterase. The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665.	3.02861e-12
NZ_CP025096.1\|WP_100992026.1\|6816326_6817853_-\|sulfatase	gnl\|CDD\|293751	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase). N-sulfoglucosamine sulfohydrolase (SGSH) belongs to the sulfatase family and catalyses the cleavage of N-linked sulfate groups from the GAGs heparin sulfate and heparin. The active site is characterized by the amino-acid sequence motif C(X)PSR that is highly conserved among most sulfatases. The cysteine residue is post-translationally converted to a formylglycine (FGly) residue, which is crucial for the catalytic process. Loss of function of SGSH results a disease called mucopolysaccharidosis type IIIA (Sanfilippo A syndrome), a fatal childhood-onset neurodegenerative disease with mild facial, visceral and skeletal abnormalities.	3.46285e-152
NZ_CP025096.1\|WP_100992044.1\|6836153_6836915_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|237252	PRK12896, PRK12896, methionine aminopeptidase; Reviewed.	4.29787e-106
NZ_CP025096.1\|WP_100994097.1\|6831695_6834707_+\|serine-hydrolase	gnl\|CDD\|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	4.8016e-76
NZ_CP025096.1\|WP_100992025.1\|6814383_6816168_+\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP025096.1\|WP_100992042.1\|6830924_6831593_+\|porin-family-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.44385e-17
NZ_CP025096.1\|WP_100992032.1\|6823936_6824311_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00227173

>NZ_CP025096.1|WP_100992035.1|6826229_6826577_+|hypothetical-protein
MNASIITLTPTELHFDWGTDGLVLWIEELDGADSLAGQMSEVMDRIAFAIELQTGWDHRTDGNTLHPLYGYRLLLRDASGLWNAVQTDETGHFAGLTPLEEMDYEVAYDKVMWLD
>NZ_CP025096.1|WP_100992034.1|6825323_6826112_+|PD-(D/E)XK-nuclease-family-protein
MVSQLLTSSRQPIYTTGDDYRALSRVSNSDLTRLKEEHLGYWSVPSARFIPEKTKAFGRAFHQHLLEPETVGTVLSQFLPDMMEPTINTDALAPAQTKQLATLMRTIRQDAFCRRYLRLSERERIVLSTEPTTGIACKARLDMVYTSPKRRNTMVIDLKTTSARTQAQFLESCYTYDYDRQAAFYIDSLRNADGREWGTTKQFRFVFIGIMKQSPHRLFAVDATSIPGFIDYGRKKYRFWLRKWHDEQTTDQLVAPAWSMSA
>NZ_CP025096.1|WP_100992033.1|6824633_6825287_+|hypothetical-protein
MNTQSNSQIETIQSGNELKPNQKINELTGEVVNSGLARRYKYLEGHPRQYRFDAKEGVFNINGNEKLGRTLTFQPIAWRIFTDNILNMGTKNWAELFFIDEKNCVSAVLFHGYSVDNIFRLIEPLYYDDLTLADVVITAVAEKKENNKIQPKGVYYIANFTYKMADAEKTKELKQFAQEVKVFRQETLTDIANIKTAMNYYNPFANPVDEPALLAVG
>NZ_CP025096.1|WP_100992032.1|6823936_6824311_-|helix-turn-helix-transcriptional-regulator
MTINLRLQQLIDSLDISVLEFSRKLGEHRGEKVYHILHGRLKPRYDTLEKILVAYPQVNGDWLLRGEGLMFKVLNSPSAAITTEERLRNMEFLLFQLNERVALLQQTNDQLLEEIRGMGSGGVV
>NZ_CP025096.1|WP_100992030.1|6823242_6823725_-|hypothetical-protein
MATTSPFDPDKLDPEFYSHDPNQHGDSDYGRESEGVGTNQMGATSGMDMDSENRNMTHDTREENTGEGRSGNPKGESLGGNQEWDVNADAISEAPKGRMMSDEAAKKLSEIAENPSDDALLHRADATYLEEGDSPGEGYDPHHVGYDEKDKTDVSKDDTK
>NZ_CP025096.1|WP_100992029.1|6822072_6823068_-|GHMP-kinase
MLIETRAYARAGLLGNPSDGFFGKTIAISVRNFGASVTLYPSPELHIEPQLQDTNVFRSLYHLRDSVSTLGYHGGVPLLKAAIKKFSEYCENEHIRLPNQNFSIRYNTSIPRQVGLSGSSAIIVATFRALMQFYGVDIPQPILPNLVLATEAEELGITAGLQDRVIQCYEGCVYMDFDRETMERQGYGQYEPLDSRLLPKLYIAYNTDLGKQSGQVHNDIRTRWLKGEPVVVDTMSAIADVAREGRDAVLRQDTKSLNELVNRNFDLRAQIYNITDRNRSLIEKARSCGASASFTGSGGSIIGLYRDDAMLNRLFVELKKINARVIKPYVV
>NZ_CP025096.1|WP_100992028.1|6821119_6821983_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MIKKAVIPAAGLGTRFLPATKAQPKEMLPIIDRPTIQYVVQEAVDSGIEDILIITGKGKRAIEDHFDRNFELEMRLEEKEDQLLLDEMRRLSDMANLHYVRQRELNGLGDAIRYARHHVGNEPFAVLLGDTIMDSVIPVTQQLIDTFEQFGGSVIAVEEVPHDKVNRYGIVGGKSLSERIFELDTLIEKPSISEAPSNMAIAGRYILTPEIFAMLEQTPVGKNNEIQLTDALLLLLKRENLYAHRIEGKRHDIGNKLDFLKTTVEFALKRPEFADQFRAFLEEIVKK
>NZ_CP025096.1|WP_100992027.1|6818145_6821034_+|DUF11-domain-containing-protein
MVFQRDLDNQATILVTGMAPPAATSIEARVVPLAIGQGSVSSWTTLNRINGSTTFRGTITAQAGWYRLDVRAKTGTTLIAQTQVNRVGIGEVFIVAGQSNAAGGFQRPPNSVEDRVMTLDFRQDSLSEQLLPLRFSNTSYGANIGPSQPPHIWGPLGDKLVQRLNVPVLFLGAALGGTTSSEWQQSAAGNIGTSVNLAVYRRLGVVLLHYALRTGVRAVLWHQGEGDISSTTQQYFNNVKYVIEKSRQQVGNRPLPWVVSRVSYTQGQTNPLVIAAQNQLISNVPNVFAGPATDFLTGYDNRGGDDVHFRGAGFFRFIDTWDQSLTTAFFQQAPPLMPTDSTALITSGYTLPLTRRPGETVAVASLRSDAHEPDNQYIAQIVRVSDGNVVFESAPSTDNPILITLPFTLTNGQYQLRTKATHPVLAGSLGEPFMVQQDATPSPAFTIYRTPISGGTADSSILRFGYGYDMPSHGLLAMVQATAPVEVRVQRIDGGSFADSGWGVAPPSSQAPDSDWNSDFNYIRYYPAQNAGIDGVIPGARYRISVRKQGDTSAGLWYETVFLQRRNILYYPMEPTGPIPPVLTLNEPVASACLSGTVNVVVDVTDNVVNRGNMFSVRLSDVNGSFTNETTIGSGSTSPISLTLSPSLPAGTNYRIRIVASNPAVASAPSQPLSICAGGADLSLNMSVSNRTPTTSQPVTITMVLANAGPFAATNVRAQSILPAGMAFVDSPSGNVSASANTVTIQAGSLPVGSRQPFVFRVRASQSGSYATSAQITASGQFDADSQPNSGTGDGQDDEATVDMRTPDASGPQIRSPNSNQAAPPIVQSNQPPTDSAKADLSLNLSASKLVVSSGEVMSVTLVCSNRGGATASNVSLQTLLPTGWRLNVTTGLTINGQTITVPIGTIPAGGSKAMVLQVRVSGSGTIRSQVLSATPIDSDSTPGNGLNKGEDDEASLSLRVR
>NZ_CP025096.1|WP_100992026.1|6816326_6817853_-|sulfatase
MSFAFNRFLIGLYIVGGLLGKFAWKNHLKSREYFRYQTDTRPNIVLIVADDHGREALGCYGNLNPTGTLPVKPTIRTPHIDQLAADGARFSNAFCTTASCSPSRSVLLTGQHNHANGMYGLEHQEHHFSSFDTVQSLPVLLEKAGYRTARIGKLHVAPEKVYHFQQVLKAGGVNDPASIGRSPVEMARQCYSFLDDKSADASHPFFLYFATDDPHRSNTVAPDGSPVFDGSKPNLFGNRPGGYPQVGDHFYQPRDVRVPAYLPDTKACRAELAQYYESIGRLDAGVGRLIDYLKDTGHYDNTLIIYLSDNGAPFPGAKTTLYEPGMRLPCIIKLPKPQKPGFVQDAMISWVDITPTLLDFANAWPGNTHKQGRSFKSIIEQERVQGWDDVYASHSLHEVTMYYPMRVLRERRYKLIVNLAHQLPYPMALDLYNSFTWQDILRTKQTHFGKRTVTAYLQRPRLELYDLQTDPDEVKNLAANPHYRDVLTRMQTKLNQFQKQTRDPWVDK
>NZ_CP025096.1|WP_100992025.1|6814383_6816168_+|aspartate--tRNA-ligase
MLRTHTCGELRLTDHNTTATLCGWVQTIRDKGGVLWIDLRDRYGITQLLLEDGQTAPELFTMARSLGREFVMKATGTVIERKSKNPNIPTGEVELKVTALEILNPAKLPPFLIEDETDGGDDLRMKYRYLDLRRNPVRRSLELRHRMAQQTRVYMDGQDFIEVETPVLIKSTPEGARDFVVPSRMNPGEFYALPQSPQTFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDILNMFEGLIRHLFKAVKGIDMAEVPRMTYAEAMKRYGSDKPDTRFGMEFVELKGTFDTVDMTSGKGFGVFDSAEMVVGINVPGCAHYTRKQLDELTDWIKRPQIGAKGLIYVRYNEDRDGEPGTLKSSVDKFYSEADLKAWAAHFGAKPGDLMLILSGDCAKARKQLNELRLEMGSRLGLRDPNVFSTLWVLDFPLLEYGEEENRWFAMHHPFTSPKPEDIPLLDTDLGAVRANAYDLVINGTEVGGGSIRIFNRDLQARMFSILGFSDEEAKAQFGFLMDAFEFGAPPHGGLAFGFDRLCSLFGGVDSIRDFIAFPKNNSGRDVMIDSPSPISQAQLNELKIATIAK
>NZ_CP025096.1|WP_100992037.1|6827586_6828780_+|DUF748-domain-containing-protein
MKRATKIFLALVVLLIIARLLLPYFVLRYVNKTLADMGGGYTGHVEDIDIQLIRGAYQIDDLRIRKISGKVKEPFIYIPKTDLSVEWKSLFKGKLVSEVETYEPEINFAFSESEASSQTGADVDWTAYLKKLLPISINRFAIVNGKVNLISLVTHPRADLSIQKFQGEIRNIRNVEDKNKKLPSPVVASGDVPGYGGTMNFSANMNFLKIVPDFDYNLRFSDLQLVKLNPLAKEYANIDFERGTVSVYSEMAMLDSKLNGYLKPLTKGMQIFKLNEHEGRSVGKFFTELLAQGGTAILKNQKHDQVATRIPLNGTIDNIETFVWPTIFGVLRNAYIEAFQGKFDNNITLKDALKSVKEDFKEKRIERKAERKEKRAERKAERKKKRAERKAKKKNKD
>NZ_CP025096.1|WP_100992038.1|6828896_6829223_-|hypothetical-protein
MIKLMLGVALMTTTALAQTTPSSNKASEPKSMTAGVNNPKSKSAVTARSNKPIPPPSQKDNLESKDNAIPSYKQEKDAGVRKGKNRYAPRRTASGARADTLLYRKPKQ
>NZ_CP025096.1|WP_100992039.1|6829252_6829528_-|hypothetical-protein
MKRFMFGMLGIILSVSAFGQSGQTPTMQQSTSTTDTRQANPARPKMKTNRQERMKMEAGLDTTLPKNRKQKRLPPDSLRRGGATKVDSVRR
>NZ_CP025096.1|WP_100992040.1|6829713_6830316_+|sigma-70-family-RNA-polymerase-sigma-factor
MFLKLFRKPRPSTDRSRSDPADYIATYRATGDLAVLGELYEQHMDLVYAVCFNYLRDEDEAKDAVMSLFEQLVTDLKKHDVQQFGPWLHSVARNYCLMQLRKNQAHPKTALVTGTGADLDDEPVMRIAEDDSDLLDLEEDLTTMEACLQTLPPEQKTCLTLFYLEKKTYTEVADLTGYDLKQVKSYLQNGRRKLKICMSK
>NZ_CP025096.1|WP_100992041.1|6830369_6830786_+|hypothetical-protein
MIDQLTFDDLRAYQSGQLSGPARYRVERLLLENPFYADALAGLEAMQQTAANTSAHPTTEQLAELRDALHERIHASATKKRLWPLWIATTTAAILFMLAVAIYLIFFAPKQPVKSIPKPTPAVTSSVFSNTVFGAVTA
>NZ_CP025096.1|WP_100992042.1|6830924_6831593_+|porin-family-protein
MFRANSLRITLLSFLFLTGCLSGSFAQQRFSAGPRVGLNLSTFGMDAKGYTLRPGVTAGAFLMYSSLNHFGISGDVLYSQMGGKYNQSNDSFKQRINYLEIPVALRYFLTLNGNFRPNVFFGPSLGFKLNAKRTNYINQGVVKQDFDNSAQFRSMDLGLVAGFQLNFKGLAERQRFLIDARYRYGLSDITLDDNQNVNNSTITLTLGYGFGVGPEYRSRYRK
>NZ_CP025096.1|WP_100994097.1|6831695_6834707_+|serine-hydrolase
MPFCRFAFFGFLSVLLSLTTFAQTTSPTFLKLNPRQACWVDSVFTNMKPEDRIAQLIMVAGYSNRKPGYEDSLITLVRTNKLGGVVMFQGGPVRQARLTNRLQASSPVPLLIAMDAEWGIAMRLDSTVRYPYQMTLGAMQGAGSDSLIYQMGANLAKQARRLGMHVNFAPSVDVNNNPNNPVINFRSFGENKYEVARKALAYMRGMQDNQLLTSLKHFPGHGDTGTDSHYDLPLIAKSRAQLDSLELYPFQQLIKAGAAGVMIAHLSIPALDTTRNRPSTLSPAIVTNLLKNELGFQGLVFSDAMNMKGVTKYFPSGKADELGIEAGMDVLEFTEDVPAALAQIKQAIVDGRISQASIDARCLKVLKAKAWVGLDQYKPIEMENLVSDLNPVQDELLNRKFTESSLTVLKNDKGLLPLQRLDTLRIASVAVESDKITAFQQMASNYTQVDHFNLTSRTPDSTLAMIRDSLKNYNLILVDVHLNNIRPAVKYGLQAKTAGLVGELVATGKAIVTVFGNVYALDKLTFPMDTVQPSRNIEQARAIIMPYQLTNYTEELSAQLIFGAIGASGKLPVTVNQRFRLGDGLPVKSIGRLKYTIPEEVGINGKFLAQQVDSLVNVGISQGAFPGCVVQMAKDGKVIFRKAYGKHTYDASLGAEPLPVQLDDLYDMASVTKVSTSTPALMHLVDDGKFNLNGKMADYLPGFKKSNKADLLWRDVLTHQARLKAWIPFWMDTKNPDGTWKPKTFKAERSGRYPIEVTDSLYEFKNYPKTIFEQIKDSPLNAKKEYVYSDLSFILYPQIVKRLTGIDFEDYLKTTFYKPLGATTLTFLPRRYYSLSRIVPTEYDSLFRKTLIWGRVHDEGAAMLNGLSGHAGLFGNANDLMKVYEMYRQKGSYGGQQFISAKTIAEFTRYQFPELGNRRGLGFDKPSFTYTGNAPKSATKASYGHSGYTGTFVWVEPDPAYKLTYIFLCNRVYPTRNNPKLGNLNTRTNIVEALYQATKRGLQ
>NZ_CP025096.1|WP_100992043.1|6834703_6835171_+|damage-inducible-protein-DinB
MKDHLIQLLDYELWANQRIIESLDTLNSPPARAIAVMGHILSAQHVWFGRVMHATTFVTIWEDIPVSWMIETAERQHRQIVSHVHALNDSELFELVEYVNTKDMRYKSSLLDILTHLSHHAAYHRGQVVQLIRPMLNEAPVTDFIVFTRENQRVK
>NZ_CP025096.1|WP_100994098.1|6835567_6836038_+|hypothetical-protein
MAQLLLSLFILNMSVALGAGLYEVRMIVHLWFPGSIKSGFQINSRAIRDIDSGRKFWAFVTTGPLTLLTIANLVLAWQSQLPGCEWWLTAALLILIERISTFSFFIPVAIKLQAPNPPPPERVNRLAALWIGFNYVRNSLTLLAWVFALRAFAFVV
>NZ_CP025096.1|WP_100992044.1|6836153_6836915_-|type-I-methionyl-aminopeptidase
MSLKSEEDLAGMQQISQVVGSTLKRMQEYARPGMSTLELDQYGGKLLELHGARSAPKLTYGFPGWTCISLNEEVCHGIPSAKRFLREGDLVNIDVSAELNGYWSDNGGSFVLGQDIHQHSDLVETSKRILAKAISHIRGGVKIAEIGRLIDNEARRSGYRVIKNLAGHGIGRSLHEEPLEILCYYDRSNKARFRTNSVVAIETFLSTRATYAQEKGDGWTLVAKDSFAVQHEQTIVITDKQPIILTAANRLWE

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Crispr_ID: NZ_CP025096_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_6

7325678-7329270

Unclear

NA:I-A,II-B,III-A

Consensus_repeat	Method
ATTTCAATTCCACTCTGGTACGATTAAAAG	CRISPRCasFinder
ATTTCAATTCCACTCTGGTACGATTA	CRT
ATTTCAATTCCACTCTGGTACGATTAAAAG	PILER-CR

54 spacers

cas2,cas1,cas4,PD-DExK,cas3,cas7,cas6,WYL

The CRISPR arrays of NZ_CP025096_6

>merge|NZ_CP025096|6|7325678-7329270|CRISPRCasFinder,CRT,PILER-CR
GTTGCAAGTCCACTCTGGTACGATTAGAAGCGGGATCAATGCCACAGACATAGTTCGTCTTTAACTATTTCAATTCCACTCTGGTACGATTAGAAGTTCCCACGGCACCACTTGCAATCCTACTGCCTGTCCGAATTTCAATTCCACTCTGGTACGATTAGAAGTCTTTCCCCGCAACAATTACAACAGATCTAACTAAAATTTCAATTCCACTCTGGTACGATTAGAAGGCAATTATTCCGTACCCCAACCCGGTCCCAAACCCATATTTCAATTCCACTCTGGTACGATTAGAAGGATTACGGCCAATTGTGATTTTATGATCCATTTGCCTATTTCAATTCCACTCTGGTACGATTAGAAGACATACAGGCTTAAGTTCGCTCAATCCTTTTACCCATTTCAATTCCACTCTGGTACGATTAGAAGATTGTTTATACGTCCTCCGTACCCCTTTTTCTCCCATATTTCAATTCCACTCTGGTACGATTAGAAGCAAAAAGAATAAAGAAATTGACCGCTTGCAGTCCATATTTCAATTCCACTCTGGTACGATTAGAAGTCAACGCAAACCCGACCAATTATATAAAATTCAAATTTCAATTCCACTCTGGTACGATTAGAAGGCACTCGCTACGGCCACAGCTACAGCCGTAAATATATTTCAATTCCACTCTGGTACGATTAGAAGCTTGCAAGGCTTGTAGTGAACCGCCAACGGCATACGTATTTCAATTCCACTCTGGTACGATTAGAAGCGGATTAAATTTTCCGCTCCTTTGAGTTTAGTCAAATTTCAATTCCACTCTGGTACGATTAGAAGGCACTAATGATGCTTGTCTTTACTGCCGGAAACTTCATTTCAATTCCACTCTGGTACGATTAGAAGCGCTTACCAGTGACTCAAGCTATACCGGTATTGGTAATTTCAATTCCACTCTGGTACGATTAGAAGGGCTGAATTAGAAATGATAAACGTTTTCCTGTCGGTATTTCAATTCCACTCTGGTACGATTAGAAGGATTCAATCCGCAGCGGATTCAGGTCTGAACTTAAATTTCAATTCCACTCTGGTACGATTAGAAGTTGGCCACTCCGAACGGGTTGCCCCCGTTGTCCGAATTTCAATTCCACTCTGGTACGATTAGAAGGAGTTCCATGCGCCGACGTGGGCGTATAGGTTTATATTTCAATTCCACTCTGGTACGATTAGAAGCAAGGCATCAAGACTAGCCGGGGGCTTTATTGCCAGATTTCAATTCCACTCTGGTACGATTAGAAGCACTTCCCTTTGAGGGGGCTATCATTGTTCATCCAGAATTTCAATTCCACTCTGGTACGATTAGAAGAGGATTTAGTATCCATTAGAATGCTCTATAGCCACATATTTCAATTCCACTCTGGTACGATTAGAAGGGACGCCTTCCCGCACCGGCATCTGATCGGGTATTATTTCAATTCCACTCTGGTACGATTAGAAGGGAGTATCTGGGCAATATCTCATTGATTCTGAAGAATTTCAATTCCACTCTGGTACGATTAGAAGAAGGATTGGAAGGGCTTGAGGAAGCGTTTAAAGAAATTTCAATTCCACTCTGGTACGATTAGAAGACGGCTGTTTCGGAAGACGATAAGCTGAATTATCTGAATTTCAATTCCACTCTGGTACGATTAGAAGTCCTGATTCGACAACTCATCCAGCCCGGCCTGTGAAATTTCAATTCCACTCTGGTACGATTAAAAGTGCAAATCTTCCTCGAACGATTCAACGATGCTTTCGAATTTCAATTCCACTCTGGTACGATTAAAAGTCATGCTGATGCACTTGGAGCGGGTGGTAATGTTGTATTTCAATTCCACTCTGGTACGATTAAAAGACAACCGGGGCGAAGCCGGTAAGTGCATCTGGTACAATTTCAATTCCACTCTGGTACGATTAAAAGATTCGGGCTTGACCAGCAGGGCCCGCAACGGGGCGAAATTTCAATTCCACTCTGGTACGATTAAAAGCAATCACAAACCTACCCGCACCGGTGCCAGTGCCATATTTCAATTCCACTCTGGTACGATTAAAAGAAGCGTTCTTTTGATTGCCTCTGGCTGGTAGGGTTATTTCAATTCCACTCTGGTACGATTAAAAGCAAGTAGGATACCGTAAAGAAGCCGTTCCCGGTTCTAATTTCAATTCCACTCTGGTACGATTAAAAGCTAACAGCAGCAGCCAATCCAAACTAGATACTGGAACATTTCAATTCCACTCTGGTACGATTAAAAGCCGGCGGCTAACACGGTACTCGCGGGTACTTTATGAATTTCAATTCCACTCTGGTACGATTAAAAGTAGAAATGGTAAACCAAAACACCCACGGGCATTTTATTTCAATTCCACTCTGGTACGATTAAAAGGAAGTTGTCGGCCACGACGCGGGTGTTCTGTACGATATTTCAATTCCACTCTGGTACGATTAAAAGTTAAGGTGATCTGGTTGTTGTCGCCCAGTGAGATAAATTTCAATTCCACTCTGGTACGATTAAAAGGTGCGGGCTCGGCAACATTCCGGTTAAAGATTGCCAAATTTCAATTCCACTCTGGTACGATTAAAAGTGTGTTCAGGCCCGCGTGATACCCCAGAAATACGTATTTCAATTCCACTCTGGTACGATTAAAAGTGTCTTGGCGGCTTCGCCCTGCTCTTTCTGTCGGTATTTCAATTCCACTCTGGTACGATTAAAAGTACGTCAAAATCCTCCAAATCGTTAAGCATCGGAAAATTTCAATTCCACTCTGGTACGATTAAAAGTCAAAAACGGCGTGATGAATCTATCCGGTCAGATATTTCAATTCCACTCTGGTACGATTAAAAGTAAAGGCGGACGACGTGATTGACTCCCTGGTTAAGGATTTCAATTCCACTCTGGTACGATTAAAAGCCAAGTGCGTCAGGGGGAAGCACACTCTCTACGTTATTTCAATTCCACTCTGGTACGATTAAAAGAACGGCGGCCTGTCCGGAAACACCACTTTCACGATATTTCAATTCCACTCTGGTACGATTAAAAGTAAAGCCTGCATTCGTGTTTCTGATTCGTTCCTGAAATTTCAATTCCACTCTGGTACGATTAAAAGATCGTTTAGCACAAGACATTAGGTTCTACCTGTATGGATTTCAATTCCACTCTGGTACGATTAAAAGTGCCGACGTTTTAGTGCCGGTCGTGCCCATCAACAAATTTCAATTCCACTCTGGTACGATTAAAAGGTGATCGCTTCACGTTCCGGGTGCCGCCCATCACGATATTTCAATTCCACTCTGGTACGATTAAAAGGCCCCACTTTTCATCCCGCAGCGGGTGTTCCTCGTTCATTTCAATTCCACTCTGGTACGATTAAAAGAACAATTGAGGTTAAAACGTCGGTTCTTGCTCCCGAATTTCAATTCCACTCTGGTACGATTAAAAGGCTTCGGCATTGGCCGGGCGCTCGGCGGGGCCATCAAAATTTCAATTCCACTCTGGTACGATTAAAAGTGTGTCGCAGGAAAAGCCTGTTAATCCTGAGCGTAATTTCAATTCCACTCTGGTACGATTAAAAG

>NZ_CP025096|6|6|7325678-7329270|CRISPRCasFinder
GTTGCAAGTCCACTCTGGTACGATTAGAAG	CGGGATCAATGCCACAGACATAGTTCGTCTTTAACT
ATTTCAATTCCACTCTGGTACGATTAGAAG	TTCCCACGGCACCACTTGCAATCCTACTGCCTGTCCGA
ATTTCAATTCCACTCTGGTACGATTAGAAG	TCTTTCCCCGCAACAATTACAACAGATCTAACTAAA
ATTTCAATTCCACTCTGGTACGATTAGAAG	GCAATTATTCCGTACCCCAACCCGGTCCCAAACCCAT
ATTTCAATTCCACTCTGGTACGATTAGAAG	GATTACGGCCAATTGTGATTTTATGATCCATTTGCCT
ATTTCAATTCCACTCTGGTACGATTAGAAG	ACATACAGGCTTAAGTTCGCTCAATCCTTTTACCC
ATTTCAATTCCACTCTGGTACGATTAGAAG	ATTGTTTATACGTCCTCCGTACCCCTTTTTCTCCCAT
ATTTCAATTCCACTCTGGTACGATTAGAAG	CAAAAAGAATAAAGAAATTGACCGCTTGCAGTCCAT
ATTTCAATTCCACTCTGGTACGATTAGAAG	TCAACGCAAACCCGACCAATTATATAAAATTCAA
ATTTCAATTCCACTCTGGTACGATTAGAAG	GCACTCGCTACGGCCACAGCTACAGCCGTAAATAT
ATTTCAATTCCACTCTGGTACGATTAGAAG	CTTGCAAGGCTTGTAGTGAACCGCCAACGGCATACGT
ATTTCAATTCCACTCTGGTACGATTAGAAG	CGGATTAAATTTTCCGCTCCTTTGAGTTTAGTCAA
ATTTCAATTCCACTCTGGTACGATTAGAAG	GCACTAATGATGCTTGTCTTTACTGCCGGAAACTTC
ATTTCAATTCCACTCTGGTACGATTAGAAG	CGCTTACCAGTGACTCAAGCTATACCGGTATTGGTA
ATTTCAATTCCACTCTGGTACGATTAGAAG	GGCTGAATTAGAAATGATAAACGTTTTCCTGTCGGT
ATTTCAATTCCACTCTGGTACGATTAGAAG	GATTCAATCCGCAGCGGATTCAGGTCTGAACTTAA
ATTTCAATTCCACTCTGGTACGATTAGAAG	TTGGCCACTCCGAACGGGTTGCCCCCGTTGTCCGA
ATTTCAATTCCACTCTGGTACGATTAGAAG	GAGTTCCATGCGCCGACGTGGGCGTATAGGTTTAT
ATTTCAATTCCACTCTGGTACGATTAGAAG	CAAGGCATCAAGACTAGCCGGGGGCTTTATTGCCAG
ATTTCAATTCCACTCTGGTACGATTAGAAG	CACTTCCCTTTGAGGGGGCTATCATTGTTCATCCAGA
ATTTCAATTCCACTCTGGTACGATTAGAAG	AGGATTTAGTATCCATTAGAATGCTCTATAGCCACAT
ATTTCAATTCCACTCTGGTACGATTAGAAG	GGACGCCTTCCCGCACCGGCATCTGATCGGGTATT
ATTTCAATTCCACTCTGGTACGATTAGAAG	GGAGTATCTGGGCAATATCTCATTGATTCTGAAGA
ATTTCAATTCCACTCTGGTACGATTAGAAG	AAGGATTGGAAGGGCTTGAGGAAGCGTTTAAAGAA
ATTTCAATTCCACTCTGGTACGATTAGAAG	ACGGCTGTTTCGGAAGACGATAAGCTGAATTATCTGA
ATTTCAATTCCACTCTGGTACGATTAGAAG	TCCTGATTCGACAACTCATCCAGCCCGGCCTGTGAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	TGCAAATCTTCCTCGAACGATTCAACGATGCTTTCGA
ATTTCAATTCCACTCTGGTACGATTAAAAG	TCATGCTGATGCACTTGGAGCGGGTGGTAATGTTGT
ATTTCAATTCCACTCTGGTACGATTAAAAG	ACAACCGGGGCGAAGCCGGTAAGTGCATCTGGTACA
ATTTCAATTCCACTCTGGTACGATTAAAAG	ATTCGGGCTTGACCAGCAGGGCCCGCAACGGGGCGAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	CAATCACAAACCTACCCGCACCGGTGCCAGTGCCAT
ATTTCAATTCCACTCTGGTACGATTAAAAG	AAGCGTTCTTTTGATTGCCTCTGGCTGGTAGGGTT
ATTTCAATTCCACTCTGGTACGATTAAAAG	CAAGTAGGATACCGTAAAGAAGCCGTTCCCGGTTCTA
ATTTCAATTCCACTCTGGTACGATTAAAAG	CTAACAGCAGCAGCCAATCCAAACTAGATACTGGAAC
ATTTCAATTCCACTCTGGTACGATTAAAAG	CCGGCGGCTAACACGGTACTCGCGGGTACTTTATGA
ATTTCAATTCCACTCTGGTACGATTAAAAG	TAGAAATGGTAAACCAAAACACCCACGGGCATTTT
ATTTCAATTCCACTCTGGTACGATTAAAAG	GAAGTTGTCGGCCACGACGCGGGTGTTCTGTACGAT
ATTTCAATTCCACTCTGGTACGATTAAAAG	TTAAGGTGATCTGGTTGTTGTCGCCCAGTGAGATAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	GTGCGGGCTCGGCAACATTCCGGTTAAAGATTGCCAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	TGTGTTCAGGCCCGCGTGATACCCCAGAAATACGT
ATTTCAATTCCACTCTGGTACGATTAAAAG	TGTCTTGGCGGCTTCGCCCTGCTCTTTCTGTCGGT
ATTTCAATTCCACTCTGGTACGATTAAAAG	TACGTCAAAATCCTCCAAATCGTTAAGCATCGGAAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	TCAAAAACGGCGTGATGAATCTATCCGGTCAGAT
ATTTCAATTCCACTCTGGTACGATTAAAAG	TAAAGGCGGACGACGTGATTGACTCCCTGGTTAAGG
ATTTCAATTCCACTCTGGTACGATTAAAAG	CCAAGTGCGTCAGGGGGAAGCACACTCTCTACGTT
ATTTCAATTCCACTCTGGTACGATTAAAAG	AACGGCGGCCTGTCCGGAAACACCACTTTCACGAT
ATTTCAATTCCACTCTGGTACGATTAAAAG	TAAAGCCTGCATTCGTGTTTCTGATTCGTTCCTGAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	ATCGTTTAGCACAAGACATTAGGTTCTACCTGTATGG
ATTTCAATTCCACTCTGGTACGATTAAAAG	TGCCGACGTTTTAGTGCCGGTCGTGCCCATCAACAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	GTGATCGCTTCACGTTCCGGGTGCCGCCCATCACGAT
ATTTCAATTCCACTCTGGTACGATTAAAAG	GCCCCACTTTTCATCCCGCAGCGGGTGTTCCTCGTTC
ATTTCAATTCCACTCTGGTACGATTAAAAG	AACAATTGAGGTTAAAACGTCGGTTCTTGCTCCCGA
ATTTCAATTCCACTCTGGTACGATTAAAAG	GCTTCGGCATTGGCCGGGCGCTCGGCGGGGCCATCAAA
ATTTCAATTCCACTCTGGTACGATTAAAAG	TGTGTCGCAGGAAAAGCCTGTTAATCCTGAGCGTA
ATTTCAATTCCACTCTGGTACGATTAAAAG

>NZ_CP025096|6|2|7325678-7329266|CRT
GTTGCAAGTCCACTCTGGTACGATTA	GAAGCGGGATCAATGCCACAGACATAGTTCGTCTTTAACT
ATTTCAATTCCACTCTGGTACGATTA	GAAGTTCCCACGGCACCACTTGCAATCCTACTGCCTGTCCGA
ATTTCAATTCCACTCTGGTACGATTA	GAAGTCTTTCCCCGCAACAATTACAACAGATCTAACTAAA
ATTTCAATTCCACTCTGGTACGATTA	GAAGGCAATTATTCCGTACCCCAACCCGGTCCCAAACCCAT
ATTTCAATTCCACTCTGGTACGATTA	GAAGGATTACGGCCAATTGTGATTTTATGATCCATTTGCCT
ATTTCAATTCCACTCTGGTACGATTA	GAAGACATACAGGCTTAAGTTCGCTCAATCCTTTTACCC
ATTTCAATTCCACTCTGGTACGATTA	GAAGATTGTTTATACGTCCTCCGTACCCCTTTTTCTCCCAT
ATTTCAATTCCACTCTGGTACGATTA	GAAGCAAAAAGAATAAAGAAATTGACCGCTTGCAGTCCAT
ATTTCAATTCCACTCTGGTACGATTA	GAAGTCAACGCAAACCCGACCAATTATATAAAATTCAA
ATTTCAATTCCACTCTGGTACGATTA	GAAGGCACTCGCTACGGCCACAGCTACAGCCGTAAATAT
ATTTCAATTCCACTCTGGTACGATTA	GAAGCTTGCAAGGCTTGTAGTGAACCGCCAACGGCATACGT
ATTTCAATTCCACTCTGGTACGATTA	GAAGCGGATTAAATTTTCCGCTCCTTTGAGTTTAGTCAA
ATTTCAATTCCACTCTGGTACGATTA	GAAGGCACTAATGATGCTTGTCTTTACTGCCGGAAACTTC
ATTTCAATTCCACTCTGGTACGATTA	GAAGCGCTTACCAGTGACTCAAGCTATACCGGTATTGGTA
ATTTCAATTCCACTCTGGTACGATTA	GAAGGGCTGAATTAGAAATGATAAACGTTTTCCTGTCGGT
ATTTCAATTCCACTCTGGTACGATTA	GAAGGATTCAATCCGCAGCGGATTCAGGTCTGAACTTAA
ATTTCAATTCCACTCTGGTACGATTA	GAAGTTGGCCACTCCGAACGGGTTGCCCCCGTTGTCCGA
ATTTCAATTCCACTCTGGTACGATTA	GAAGGAGTTCCATGCGCCGACGTGGGCGTATAGGTTTAT
ATTTCAATTCCACTCTGGTACGATTA	GAAGCAAGGCATCAAGACTAGCCGGGGGCTTTATTGCCAG
ATTTCAATTCCACTCTGGTACGATTA	GAAGCACTTCCCTTTGAGGGGGCTATCATTGTTCATCCAGA
ATTTCAATTCCACTCTGGTACGATTA	GAAGAGGATTTAGTATCCATTAGAATGCTCTATAGCCACAT
ATTTCAATTCCACTCTGGTACGATTA	GAAGGGACGCCTTCCCGCACCGGCATCTGATCGGGTATT
ATTTCAATTCCACTCTGGTACGATTA	GAAGGGAGTATCTGGGCAATATCTCATTGATTCTGAAGA
ATTTCAATTCCACTCTGGTACGATTA	GAAGAAGGATTGGAAGGGCTTGAGGAAGCGTTTAAAGAA
ATTTCAATTCCACTCTGGTACGATTA	GAAGACGGCTGTTTCGGAAGACGATAAGCTGAATTATCTGA
ATTTCAATTCCACTCTGGTACGATTA	GAAGTCCTGATTCGACAACTCATCCAGCCCGGCCTGTGAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGTGCAAATCTTCCTCGAACGATTCAACGATGCTTTCGA
ATTTCAATTCCACTCTGGTACGATTA	AAAGTCATGCTGATGCACTTGGAGCGGGTGGTAATGTTGT
ATTTCAATTCCACTCTGGTACGATTA	AAAGACAACCGGGGCGAAGCCGGTAAGTGCATCTGGTACA
ATTTCAATTCCACTCTGGTACGATTA	AAAGATTCGGGCTTGACCAGCAGGGCCCGCAACGGGGCGAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGCAATCACAAACCTACCCGCACCGGTGCCAGTGCCAT
ATTTCAATTCCACTCTGGTACGATTA	AAAGAAGCGTTCTTTTGATTGCCTCTGGCTGGTAGGGTT
ATTTCAATTCCACTCTGGTACGATTA	AAAGCAAGTAGGATACCGTAAAGAAGCCGTTCCCGGTTCTA
ATTTCAATTCCACTCTGGTACGATTA	AAAGCTAACAGCAGCAGCCAATCCAAACTAGATACTGGAAC
ATTTCAATTCCACTCTGGTACGATTA	AAAGCCGGCGGCTAACACGGTACTCGCGGGTACTTTATGA
ATTTCAATTCCACTCTGGTACGATTA	AAAGTAGAAATGGTAAACCAAAACACCCACGGGCATTTT
ATTTCAATTCCACTCTGGTACGATTA	AAAGGAAGTTGTCGGCCACGACGCGGGTGTTCTGTACGAT
ATTTCAATTCCACTCTGGTACGATTA	AAAGTTAAGGTGATCTGGTTGTTGTCGCCCAGTGAGATAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGGTGCGGGCTCGGCAACATTCCGGTTAAAGATTGCCAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGTGTGTTCAGGCCCGCGTGATACCCCAGAAATACGT
ATTTCAATTCCACTCTGGTACGATTA	AAAGTGTCTTGGCGGCTTCGCCCTGCTCTTTCTGTCGGT
ATTTCAATTCCACTCTGGTACGATTA	AAAGTACGTCAAAATCCTCCAAATCGTTAAGCATCGGAAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGTCAAAAACGGCGTGATGAATCTATCCGGTCAGAT
ATTTCAATTCCACTCTGGTACGATTA	AAAGTAAAGGCGGACGACGTGATTGACTCCCTGGTTAAGG
ATTTCAATTCCACTCTGGTACGATTA	AAAGCCAAGTGCGTCAGGGGGAAGCACACTCTCTACGTT
ATTTCAATTCCACTCTGGTACGATTA	AAAGAACGGCGGCCTGTCCGGAAACACCACTTTCACGAT
ATTTCAATTCCACTCTGGTACGATTA	AAAGTAAAGCCTGCATTCGTGTTTCTGATTCGTTCCTGAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGATCGTTTAGCACAAGACATTAGGTTCTACCTGTATGG
ATTTCAATTCCACTCTGGTACGATTA	AAAGTGCCGACGTTTTAGTGCCGGTCGTGCCCATCAACAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGGTGATCGCTTCACGTTCCGGGTGCCGCCCATCACGAT
ATTTCAATTCCACTCTGGTACGATTA	AAAGGCCCCACTTTTCATCCCGCAGCGGGTGTTCCTCGTTC
ATTTCAATTCCACTCTGGTACGATTA	AAAGAACAATTGAGGTTAAAACGTCGGTTCTTGCTCCCGA
ATTTCAATTCCACTCTGGTACGATTA	AAAGGCTTCGGCATTGGCCGGGCGCTCGGCGGGGCCATCAAA
ATTTCAATTCCACTCTGGTACGATTA	AAAGTGTGTCGCAGGAAAAGCCTGTTAATCCTGAGCGTA
ATTTCAATTCCACTCTGGTACGATTA

>NZ_CP025096|6|2|7325679-7329270|PILER-CR
TTGCAAGTCCACTCTGGTACGATTAGAAGC	GGGATCAATGCCACAGACATAGTTCGTCTTTAACTA
TTTCAATTCCACTCTGGTACGATTAGAAGT	TCCCACGGCACCACTTGCAATCCTACTGCCTGTCCGAA
TTTCAATTCCACTCTGGTACGATTAGAAGT	CTTTCCCCGCAACAATTACAACAGATCTAACTAAAA
TTTCAATTCCACTCTGGTACGATTAGAAGG	CAATTATTCCGTACCCCAACCCGGTCCCAAACCCATA
TTTCAATTCCACTCTGGTACGATTAGAAGG	ATTACGGCCAATTGTGATTTTATGATCCATTTGCCTA
TTTCAATTCCACTCTGGTACGATTAGAAGA	CATACAGGCTTAAGTTCGCTCAATCCTTTTACCCA
TTTCAATTCCACTCTGGTACGATTAGAAGA	TTGTTTATACGTCCTCCGTACCCCTTTTTCTCCCATA
TTTCAATTCCACTCTGGTACGATTAGAAGC	AAAAAGAATAAAGAAATTGACCGCTTGCAGTCCATA
TTTCAATTCCACTCTGGTACGATTAGAAGT	CAACGCAAACCCGACCAATTATATAAAATTCAAA
TTTCAATTCCACTCTGGTACGATTAGAAGG	CACTCGCTACGGCCACAGCTACAGCCGTAAATATA
TTTCAATTCCACTCTGGTACGATTAGAAGC	TTGCAAGGCTTGTAGTGAACCGCCAACGGCATACGTA
TTTCAATTCCACTCTGGTACGATTAGAAGC	GGATTAAATTTTCCGCTCCTTTGAGTTTAGTCAAA
TTTCAATTCCACTCTGGTACGATTAGAAGG	CACTAATGATGCTTGTCTTTACTGCCGGAAACTTCA
TTTCAATTCCACTCTGGTACGATTAGAAGC	GCTTACCAGTGACTCAAGCTATACCGGTATTGGTAA
TTTCAATTCCACTCTGGTACGATTAGAAGG	GCTGAATTAGAAATGATAAACGTTTTCCTGTCGGTA
TTTCAATTCCACTCTGGTACGATTAGAAGG	ATTCAATCCGCAGCGGATTCAGGTCTGAACTTAAA
TTTCAATTCCACTCTGGTACGATTAGAAGT	TGGCCACTCCGAACGGGTTGCCCCCGTTGTCCGAA
TTTCAATTCCACTCTGGTACGATTAGAAGG	AGTTCCATGCGCCGACGTGGGCGTATAGGTTTATA
TTTCAATTCCACTCTGGTACGATTAGAAGC	AAGGCATCAAGACTAGCCGGGGGCTTTATTGCCAGA
TTTCAATTCCACTCTGGTACGATTAGAAGC	ACTTCCCTTTGAGGGGGCTATCATTGTTCATCCAGAA
TTTCAATTCCACTCTGGTACGATTAGAAGA	GGATTTAGTATCCATTAGAATGCTCTATAGCCACATA
TTTCAATTCCACTCTGGTACGATTAGAAGG	GACGCCTTCCCGCACCGGCATCTGATCGGGTATTA
TTTCAATTCCACTCTGGTACGATTAGAAGG	GAGTATCTGGGCAATATCTCATTGATTCTGAAGAA
TTTCAATTCCACTCTGGTACGATTAGAAGA	AGGATTGGAAGGGCTTGAGGAAGCGTTTAAAGAAA
TTTCAATTCCACTCTGGTACGATTAGAAGA	CGGCTGTTTCGGAAGACGATAAGCTGAATTATCTGAA
TTTCAATTCCACTCTGGTACGATTAGAAGT	CCTGATTCGACAACTCATCCAGCCCGGCCTGTGAAA
TTTCAATTCCACTCTGGTACGATTAAAAGT	GCAAATCTTCCTCGAACGATTCAACGATGCTTTCGAA
TTTCAATTCCACTCTGGTACGATTAAAAGT	CATGCTGATGCACTTGGAGCGGGTGGTAATGTTGTA
TTTCAATTCCACTCTGGTACGATTAAAAGA	CAACCGGGGCGAAGCCGGTAAGTGCATCTGGTACAA
TTTCAATTCCACTCTGGTACGATTAAAAGA	TTCGGGCTTGACCAGCAGGGCCCGCAACGGGGCGAAA
TTTCAATTCCACTCTGGTACGATTAAAAGC	AATCACAAACCTACCCGCACCGGTGCCAGTGCCATA
TTTCAATTCCACTCTGGTACGATTAAAAGA	AGCGTTCTTTTGATTGCCTCTGGCTGGTAGGGTTA
TTTCAATTCCACTCTGGTACGATTAAAAGC	AAGTAGGATACCGTAAAGAAGCCGTTCCCGGTTCTAA
TTTCAATTCCACTCTGGTACGATTAAAAGC	TAACAGCAGCAGCCAATCCAAACTAGATACTGGAACA
TTTCAATTCCACTCTGGTACGATTAAAAGC	CGGCGGCTAACACGGTACTCGCGGGTACTTTATGAA
TTTCAATTCCACTCTGGTACGATTAAAAGT	AGAAATGGTAAACCAAAACACCCACGGGCATTTTA
TTTCAATTCCACTCTGGTACGATTAAAAGG	AAGTTGTCGGCCACGACGCGGGTGTTCTGTACGATA
TTTCAATTCCACTCTGGTACGATTAAAAGT	TAAGGTGATCTGGTTGTTGTCGCCCAGTGAGATAAA
TTTCAATTCCACTCTGGTACGATTAAAAGG	TGCGGGCTCGGCAACATTCCGGTTAAAGATTGCCAAA
TTTCAATTCCACTCTGGTACGATTAAAAGT	GTGTTCAGGCCCGCGTGATACCCCAGAAATACGTA
TTTCAATTCCACTCTGGTACGATTAAAAGT	GTCTTGGCGGCTTCGCCCTGCTCTTTCTGTCGGTA
TTTCAATTCCACTCTGGTACGATTAAAAGT	ACGTCAAAATCCTCCAAATCGTTAAGCATCGGAAAA
TTTCAATTCCACTCTGGTACGATTAAAAGT	CAAAAACGGCGTGATGAATCTATCCGGTCAGATA
TTTCAATTCCACTCTGGTACGATTAAAAGT	AAAGGCGGACGACGTGATTGACTCCCTGGTTAAGGA
TTTCAATTCCACTCTGGTACGATTAAAAGC	CAAGTGCGTCAGGGGGAAGCACACTCTCTACGTTA
TTTCAATTCCACTCTGGTACGATTAAAAGA	ACGGCGGCCTGTCCGGAAACACCACTTTCACGATA
TTTCAATTCCACTCTGGTACGATTAAAAGT	AAAGCCTGCATTCGTGTTTCTGATTCGTTCCTGAAA
TTTCAATTCCACTCTGGTACGATTAAAAGA	TCGTTTAGCACAAGACATTAGGTTCTACCTGTATGGA
TTTCAATTCCACTCTGGTACGATTAAAAGT	GCCGACGTTTTAGTGCCGGTCGTGCCCATCAACAAA
TTTCAATTCCACTCTGGTACGATTAAAAGG	TGATCGCTTCACGTTCCGGGTGCCGCCCATCACGATA
TTTCAATTCCACTCTGGTACGATTAAAAGG	CCCCACTTTTCATCCCGCAGCGGGTGTTCCTCGTTCA
TTTCAATTCCACTCTGGTACGATTAAAAGA	ACAATTGAGGTTAAAACGTCGGTTCTTGCTCCCGAA
TTTCAATTCCACTCTGGTACGATTAAAAGG	CTTCGGCATTGGCCGGGCGCTCGGCGGGGCCATCAAAA
TTTCAATTCCACTCTGGTACGATTAAAAGT	GTGTCGCAGGAAAAGCCTGTTAATCCTGAGCGTAA
TTTCAATTCCACTCTGGTACGATTAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100992406.1\|7331338_7332349_-\|DUF1016-domain-containing-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl\|CDD\|377634
NZ_CP025096.1\|WP_100992397.1\|7318316_7319909_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|225100
NZ_CP025096.1\|WP_100994134.1\|7312279_7315363_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238634
NZ_CP025096.1\|WP_100992401.1\|7324264_7324969_+\|DsbA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|239322
NZ_CP025096.1\|WP_100992407.1\|7332352_7334629_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP025096.1\|WP_100992411.1\|7338568_7339387_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889
NZ_CP025096.1\|WP_100990299.1\|7325129_7325393_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992400.1\|7323719_7324253_+\|YceI-family-protein	unknown	unknown	gnl\|CDD\|377274
NZ_CP025096.1\|WP_100992410.1\|7336416_7338429_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992408.1\|7334635_7335340_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273860
NZ_CP025096.1\|WP_100992395.1\|7317073_7317637_+\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NZ_CP025096.1\|WP_100992412.1\|7339530_7340511_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP025096.1\|WP_100992405.1\|7330821_7331334_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP025096.1\|WP_100992398.1\|7320046_7322686_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|350684
NZ_CP025096.1\|WP_100992403.1\|7329486_7329750_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP025096.1\|WP_100992409.1\|7335332_7336430_-\|DevR-family-CRISPR-associated-autoregulator	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NZ_CP025096.1\|WP_100992402.1\|7325429_7325660_+\|transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP025096.1\|WP_100992404.1\|7329762_7330776_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_CP025096.1\|WP_100992394.1\|7315710_7316949_+\|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|366466
NZ_CP025096.1\|WP_100992399.1\|7322979_7323582_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100992406.1\|7331338_7332349_-\|DUF1016-domain-containing-protein	gnl\|CDD\|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	3.80076e-78
NZ_CP025096.1\|WP_100992397.1\|7318316_7319909_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	5.59396e-37
NZ_CP025096.1\|WP_100994134.1\|7312279_7315363_-\|amidohydrolase-family-protein	gnl\|CDD\|238634	cd01309, Met_dep_hydrolase_C, Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	5.25892e-115
NZ_CP025096.1\|WP_100992401.1\|7324264_7324969_+\|DsbA-family-oxidoreductase	gnl\|CDD\|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	3.34887e-93
NZ_CP025096.1\|WP_100992407.1\|7332352_7334629_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.59932e-60
NZ_CP025096.1\|WP_100992411.1\|7338568_7339387_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.91017e-24
NZ_CP025096.1\|WP_100992400.1\|7323719_7324253_+\|YceI-family-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	1.75074e-54
NZ_CP025096.1\|WP_100992412.1\|7339530_7340511_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	6.88073e-24
NZ_CP025096.1\|WP_100992408.1\|7334635_7335340_-\|hypothetical-protein	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	3.91831e-11
NZ_CP025096.1\|WP_100992395.1\|7317073_7317637_+\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.01482e-09
NZ_CP025096.1\|WP_100992405.1\|7330821_7331334_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	4.96954e-55
NZ_CP025096.1\|WP_100992398.1\|7320046_7322686_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|350684	cd17926, DEXHc_RE, DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins. This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	6.43942e-05
NZ_CP025096.1\|WP_100992403.1\|7329486_7329750_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.97926e-28
NZ_CP025096.1\|WP_100992409.1\|7335332_7336430_-\|DevR-family-CRISPR-associated-autoregulator	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	1.6334e-35
NZ_CP025096.1\|WP_100992402.1\|7325429_7325660_+\|transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.11997e-18
NZ_CP025096.1\|WP_100992399.1\|7322979_7323582_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.44178e-15
NZ_CP025096.1\|WP_100992394.1\|7315710_7316949_+\|BamA/TamA-family-outer-membrane-protein	gnl\|CDD\|366466	pfam01103, Bac_surface_Ag, Surface antigen. This entry includes the following surface antigens; D15 antigen from H.influenzae, OMA87 from P.multocida, OMP85 from N.meningitidis and N.gonorrhoeae. The family also includes a number of eukaryotic proteins that are members of the UPF0140 family. There also appears to be a relationship to pfam03865 (personal obs: C Yeats). In eukaryotes, it appears that these proteins are not surface antigens; S. cerevisiae YNL026W (SAM50) is an essential component of the Sorting and Assembly Machinery (SAM) of the mitochondrial outer membrane. The protein was localized to the mitochondria.	8.61367e-08
NZ_CP025096.1\|WP_100992404.1\|7329762_7330776_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.76833e-169

>NZ_CP025096.1|WP_100992402.1|7325429_7325660_+|transposase
MSRKGNCWDNAVAESFFKTLKCEMVNHTYFATRAAARLATFEYIEGWYNRRRKHSVLNYRTPSQQESYFYTSSMAA
>NZ_CP025096.1|WP_100990299.1|7325129_7325393_+|hypothetical-protein
MQTTLDLYTDYLLSSFGQTTATGLSRLTDGAVGHDAVTDLLNRLQGDNRTLWQHVKPLIRQIQEPDGLLLTDDSIAHKPHSDENLAS
>NZ_CP025096.1|WP_100992401.1|7324264_7324969_+|DsbA-family-oxidoreductase
MDVEIWSDIMCPFCYIGKRKFEHALSQFPHKDQVNIVWKSFQLNPDMQTEPGKNINQYLSEIKGWSLDEAKQMNDRVTAMAQEVGLSYDFDKAVVANSFDAHRLIQLAKQNGLGDAIEERLFKAYFTEGRDTSDHDTLVELGTEIGLDATVIQQMLAGTEFTEAVHGDVYEAQQVGARGVPFFVLNRRYAVSGAQQPETFLGALDTAWAEWAKTNPVIPQLTADGPTCTPGEIC
>NZ_CP025096.1|WP_100992400.1|7323719_7324253_+|YceI-family-protein
MATTNWVVDPMHSEVQFKIKHLVISTVTGTFRNFEGGATTESDDFDNAEIHFSLHVDSVDTNQEMRDAHLKGADFFDAETFPKIAFKSTSFKKIDDDEYALNGDLTMKGVTKPVTLKAEYGGTAKDAYGNQKLGFEVTGKVNRKEFGLTYNALTETGGLALGEDIKLSANIQLAKAA
>NZ_CP025096.1|WP_100992399.1|7322979_7323582_+|TetR/AcrR-family-transcriptional-regulator
MGILERRLRQKVEVKTSILQAAWQLVLEEGWQALSIRKIADAIEYSVPVIYSHFENKDAILQEFTREGFQLLTEEVIWQRDTKIEASQQLEAIAQGYWDFAFTHKEFYQLMFGLGIPRCEQVNQVAEIKQFSGVLIGVIQEVISSSKQPKVDAFLKFHTYWSILHGLVSIQMIDSNSTANPWSQLVLKDAIDGYIKALNG
>NZ_CP025096.1|WP_100992398.1|7320046_7322686_+|DEAD/DEAH-box-helicase-family-protein
MELKPYQAGVIRDLDRYLHYVQQEQRYDVAYNRYWQDEVGDYDPLNNTGMRPYQNNVPGTPHVCVKVPTAGGKTFIAVNALHTLFNAFATDKPKAVVWLVPWSNLLDQTVRNLSNPAHPYRQKLNSLFNHRVAVYQKKDLLQGANFSPAVVQQQLSIFVLSFGSLRAKKKEDRKIFEENGALATFASQFESDDHLLADTDQTALINVIRSLTPVVVVDESHNAESDLSVDMLRDLNPSFVLDLTATPKKNANIVSFVSAIELKKEQMVKLPVIAYNHKEKSQVVESALNLQRQLERLAKVEQKAGGRYIRPIVLFQAQPKTGDDNTTFEKLKQQLLKLKIPEEQIKIKTADINELKDIDLMSPKCPVRYIITVNALKEGWDCPFAYILASLADRSSAVDIEQILGRVLRQPYVMRHQNDLLNVSYVLTASAKFTETLQSIIRGLESAGFSRNDYRSSDEQPVDAAPQTTAQALQGFLFPESSESASDEIEPEKIQFDPGDIADETPVEVLPTLAAITQIAVTKNQEFEQQINQQASDVPSPLFQELGDKVKKISINQDFAALAQQLALPQFYLAVPQTGLFSQGERVLLNQEVLLNGFRLADEDIKIDWNTVETDLYKIDIERTQGNQYRPVFLQLDNIQIKEAFVEYILTKPKAGQIKDLAHRMLQLIGNMYPIPDQQIKLYLERILSSFDAERLKDLLAREYTYRDKIKKKIRALADLHAEGQFEKLLVVGKISVEPNFTFRKTIVPGLLGKSLGKSLYAHEGSMNGFEERIISELAALPNVLFWHRNLGRGKGFAINGFKSNHYPDFIVYTQSGTLILLETKGDDRDNSDSAAKNRLGRTWAEQAGRQYKYFMVFDTHRLADTYTIAEVKELVKQL
>NZ_CP025096.1|WP_100992397.1|7318316_7319909_+|site-specific-DNA-methyltransferase
MPTLTWIGKDKVINHHHDVPFRILDPQYSYGTPSPDLGEGRAEGNRIIHGDNLEALKALLPYYEGRIKCIYIDPPYNTGNEGWVYNDNVSDPKLKRWLGKVVGKESEDLSRHDKWLCMMYPRLQLLHRLLADDGAIFVSIDDNEQASLKLVMDEIWGPGNFVSSIVWQKNFAPKNDAKHFSTDTESIIAYAKSLTLLKIYRLKRSEKNLQNYKNPDNDIRGLWASSDLLRMEHRDNSVYTITSPSGRQWAPEPGTSWRHPEPELIELVKNNRIWFGLDGNTKPRRKRFLSEIKEGVIPQTLWKHEEVGNTQEAKKEVNSIFKGTNERFPTPKPTRLIERILQIATGPNDIILDSFAGSGTTAHAVLNLNKQDGGNRQFILVEMEDYAETITAERVRRVIDGYGGKDGTGGEFTYYELGPALFTENGLLNEDLPLNRIREYIWYSETRLPFLSTPKTENETPHFLGKLFETAYYFYYQPNELTTLDYDFLSTVQTPAEQYVIYADNCLISPDWLQQRHIIFKKIPRDISRF
>NZ_CP025096.1|WP_100992395.1|7317073_7317637_+|pentapeptide-repeat-containing-protein
MDFCDQLFDQSTSPVDQWARQNFEQCTFKNLDLSKVVFANTSFINCRFDYCNLSAALFEGTKLDDVVFVDCKLNSVNFGQCSAFGFHVDFQTCQLDYVSFFGRNLKKTRFVDCSLLEGRFINCDLSGALFKNCNLELTLFATNVLTQTDFSSSYNLTLDPDGNKLKKTKFSVHSLRGLLTKYDIVVS
>NZ_CP025096.1|WP_100992394.1|7315710_7316949_+|BamA/TamA-family-outer-membrane-protein
MKLILGLFVSFLVVCSSALTPAVAQMPLADTIATNTTAIRHVPPQHDVADLVKRWYPRLPITQHDSSTLHEGKRFVLVIPQIGYTLQTRGLVAVLVNTPFRMANANMSSMTGQVAYTQNNQIIFTSTSSIWTRDNRFLWTNDWRLMHYPQATYGLGMYTSTDRVINMDYAYFRFHQSLLRRLAPNLYAGMGYHLDLHWNIDSYNSRREVTRISRYTNGVVGRSVSSGPTVHLLYDNRQNAINPAGGFLVNATLRANMRVLGSDDTYQSALVEVRKYVHVPANSDNILAFWSYNALTLSGNPPFLDLPSTGWDYSGNVGRGFIQGRFRGKNLLYAETEYRFHLTADRLLGGVVFANAQTVTEQNSGQFEKIVPAVGAGLRIKMNKLSRTNLSVDYGVGFDGSKGLFFNLGEVF
>NZ_CP025096.1|WP_100994134.1|7312279_7315363_-|amidohydrolase-family-protein
MTKHYLTALLAAGLAYSSVAQTTFPRNGVYDERPGLYAFTNATIVVDPQTTLQNATLLIRNGRVETVGTAVSIPAGTVITDLKGKRIYPGLVDIDSDYGMPEITRGPAGGRGGVPQYESNKKGAYYWNQAIQPENDASVLFKADTKKADELRKLGFGAVLTHPHDGIARGTGSLVILADDRENTLVLKPNVTAHYSFSKGTSGQQYPNSMMGIVALLRQAFYDADWYKRSGSKEQANMSLEALNRTQNLPAIFEANDKLGILRADKIGDEFGVQYIIRSSGDEYQRLDEVKATGASLIVPLNYPQPYDIEDAWDADNVALAELKHWEMAPMNAGRLAKANVQFALTTAGLKNKADFWANLRKAIENGLPEQKALEALTTIPAKLIRAEDELGTLKKGQIANFIITSGNLFSADNVIYENWMRGKQYIVNSKDAADLRGVWTLTVGSQSNLKLNITGKSPEKPEYQIVADTLKLTPKVAFSGDIISIQVQLDKKKPGTTRLTGYRTTPTNLKGDGESPDGKAITWSAVRTGDAPVSTTATSTSATSSTTAMASATSPASNTAATVLYPFVGMGNAQKPKAETILIRNATVWTNEKDGVLTNTDVLVTGGKISKVGKGLTAAADVKVVDGTGKHLTNGIIDEHSHIALLSINEGAQSSSAEVRMADVINPDDINIYRQLAGGVTTSQLLHGSANAIGGQSAIVKLKWGESADGMLIKGADGFIKFALGENVKQSNYPNPNVLTRFPQSRMGVEQVFVDHFTRAKEYAKGWAAYNKLSTKEKATAIAPRRDIELDALAEILANKRFITCHSYVQSEINMLLKVADSLGFKVNTFTHILEGYKLADKMAKHGAGGSSFADWWAYKMEVHDAIPYNAAIMHRQGVTVSINSDDAEMARRLNQEAAKTIEYGGMTEEDAWKMVTLNPAKLLHLDSKLGSVRAGKDADLVLWNANPLAIYARPEFTMIDGAIYFSLKDEDQKRDQMQAERARLIQKMLTAKAGGASTVRPMPKRARMWHCEDIEGVMAEGEAGK
>NZ_CP025096.1|WP_100992403.1|7329486_7329750_-|CRISPR-associated-endonuclease-Cas2
MYVILVYDMGQKRVGKMLKLCRRYMNWIQNSVFEGELTEVQLRELLHEAKRIMNEEEDSLILFKNRDLKWLDKQIVGVERQSTDNFL
>NZ_CP025096.1|WP_100992404.1|7329762_7330776_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKQPKYLFNAGRMSRKDNTLKFTPVDEAGVEEQPRYLPIEQVGDLYVFGSLDANSALYNFLGQEGIAVHFFNYYEHYTGSFMPREYLLAGKMQVDQTKHYMTAKKRIEIARRFVEGAANNILRVLKYYNNRDKVKDLTEAIVSIERLLVSVPTTTDVPMLMGIEGNIRQTYYGCFDAIVGQTFCMDGRSKRPPQNELNALISFGNMLCYTACLSTIYHTQLNPTISFLHEPGARRYSLALDLSEVFKPILVDRLIFRMINKRQLQPSDFRSEVGGCVLKDAARKRFVQGFDEQLKETIKHRALGRSVSYRHLMKLECYKLQKHLLGVEEYRPFKAWW
>NZ_CP025096.1|WP_100992405.1|7330821_7331334_-|CRISPR-associated-protein-Cas4
MFPTATLVNYLHLCHRKLWLHANHIRMEHTSEAVAEGKQLHEHAYPQRTERYREITLDGSVIDFYDPYNKVVHEMKKSDKMEHSHIAQVQFYLYLLQKNGVEGATGLIEYPKLRQTQQVSLTEEDVPMVEGWIRVIEQLVDSEKCPGRIAKSKCRSCSYFDFCYVEELPE
>NZ_CP025096.1|WP_100992406.1|7331338_7332349_-|DUF1016-domain-containing-protein
MQPNYTNFLSTIKTRIRQAQYDALRVVNQQLIKLYWDMGQLIVEKQETDGWGKSVVDQLSADLQTEFPGISGFSARNIWNMRLFYLTYKDDLILQPLVAEIAWSHNLLIVEKCKDTLQREFYLKMTRKFGWTKNVLANQLAGQAYEKYLLNQTNFDQTLPDVYQQQAKLAVKDEYTFGFLELAEEHSEAELETAIVQNIRKFLLEMGGYYTFVGNQFRMEVGGQEYFIDLLLYHRKLRCLVALELKIGEFKPEYAGKMQFYLAVLNDTVKLPDEQASIGIIVCQNKNRTIVEYALKTSDQPIGVSAYSIREELPQEFKHLLPSADEIQERLQHLNL
>NZ_CP025096.1|WP_100992407.1|7332352_7334629_-|CRISPR-associated-helicase/endonuclease-Cas3
MDFSVYKAKSDDPTHALCMTLEEHTRRVIRAATELVNRLPFTQTERTEWLEKAIRCAVWHDLGKIHPSFQLNLRKGTTVVSIRHELISLWFCEQFLTLPIDELFAIATHHKGIVSDGFKRLSFEEIGTDLSYHLTEDSKSVNNAEEIVKAWAILFDDTSPVLNNLSPATIYSHEISNLLMKDRQRNQPVDWLQLARMRGLLMAADHIGSAKTECDLPVWKRLELTDLYPTISTESKQLVRTAFRPFQIRMQEFKGDVILHAPTGSGKTEAALSWVYANQTENVRLFYILPYTASINAMVRRLKGVYGKERVTALHSKALDFFYEEAINETNNFQRSEQIARNKRSASRELFYPVKVATLHQVLKHALHGKGWDMSLFDYHNALFIVDEFHTYDAHLTGMMLATLKWLKHFCNAKILLMSATIPKFLLDRIITELFDGDKLRIVRPKAKEPADAEILKRIRHKLVCHPQQMISNSLSQITTILEESKKTVLIIVNNVKSCQELAKAFAKYEPKLLHGGFHREERSEIEKAITASDKSKRPRLLIATQAVEVSLDIDYDIAFIENAPMDALIQRFGRVNRAGKRKKPSEIHLFEQSIGNTKRIYDEAIVKETWRVLSTLDSQELSEQNLVDACDEVYVNGYTDEQERNFQIGFTHDRIANFETSFFAGDWSDWVEDVIEKSNLKIDILCHNLRCEFEKRRAEGRYIEASQLFVQVYPWECPKEYQNKLEDKQNTLVATNLKYDSGIGYQRIERSPDFNFL
>NZ_CP025096.1|WP_100992408.1|7334635_7335340_-|hypothetical-protein
MNEVLEVKFDGWTTTPRLPFVLSGNALCMTVPSYSSLLGLIGCCLGRIVSHTEVQFGFHYQYSTTGNDLETRQRLEFDGRMVKPHAKGTDAYKREFHVVSTTDSAGDLQPCLTLWLNRIDWIDYFRYPIGTPALGRSQDLLHIRFDSVKIMSVEPVSTTNVGGCALPFKSGMQVAGQLVQLADAYEEYERIGAGRKPINPRVFINLSHETNQEVTMANLFRTSEGQSFYLHNWQ
>NZ_CP025096.1|WP_100992409.1|7335332_7336430_-|DevR-family-CRISPR-associated-autoregulator
MATLNNITGALVIDGTAAFLNGAGLGAGEDRNKVVPKVFEEMINGRREKVPYVSAQAWRRWLRNTSNEENSWTPSDLQAIGVSKKGTTNKISTLLDPIAYPEDDLFGYMRSGGNDKSAASDEDEEDEAPTKTKAESVQRTSPFKCSILKGIRGKRVLNVDEGFVHLKENTPLPYSTQFYAAHLEGFFNLEYYRLGQFDNLGSKQELASETVKQYADHLTGQPLGSKGTFRRFTLKDAEQSRKERAAGLLRGLAFLRGGAKQAAFGTDVSPKVLILAGLECANPVFNNLFEGSGEMPSLKIKALQQIMDDYRNKLATPVYIGIREGYLQNEADVKALADGTNVVVGSPISVAQSFIKAHLITTPNE
>NZ_CP025096.1|WP_100992410.1|7336416_7338429_-|hypothetical-protein
MILFKDYTGNAMLNNALQTIEALAGQGISNIDADTLLKLFNNPYRDGLHTLTGLNKRLKSYTMFFSKNGPLFNDKEFGEAIYKHLITSILSNVENEGPYTCELSGLRFKTTFEVFYEQTLRKVGYPAIKINGKDKTVNRCWFPLLGGLGSDAQALPQAKFALTVHPVCLAILQFLPLSAVLYKSNLLLVDASNEDLSKRLIADHVSLIKSKATAGAATSSVENIKDYTKGHYLLRALNILASKERDDTITAFNLWCFTNSGTGASCEIDRIPSQLINDLRSLYKNPSLRPTVEGILKNSKIQSDFLDNLEGHLDFYGLYPNKNSDGVSIHFYEAYQRLIGNGERLGYAKYVAHLLSKEEWNKNQHKFLSKTDAPTSDYALYKSMVYKALVGAASRKEWHWAHHVSILNSPDKIPIDSTISRMYRMVHFYYSALSAEDDVVMPAIPDVSNQLIGQAVNVFFQVMGEDKRNYSSRWLGSRYQEVNPLPLLVREGSRFYDLDVVYALLFDLENRQIAYGLRDILRVYLNYHHNSSLPQLDVQPTNLLPIPDSEQMAYLNKLRDFANEYVAYYRDGRNKGKLDEAKFRQHVLLPMRQDNFQISQWLNNVTENMAGEINKLSGQSFASALSSEELLYDYTGRYNPAFARFALEYLLNQFYHQLTLTLTTVYYGNA
>NZ_CP025096.1|WP_100992411.1|7338568_7339387_-|CRISPR-associated-endoribonuclease-Cas6
MQFKLTLRPTASQTLVPFNYAYRLSGFIYSVIADADAQYARFLHEKGYLATSTRRFKLFTFSDLIMPNARLDARAGGMWVNSPYIEWVVSFYIDSAAQHFIMGLFQDQRCVIATPRHRAEFIIEHVEAVPVEITSQSVLLRTLSPVVIAEKDTRGMDQYLHPADAQFGPFLVSNLLAKYDSIQKTLAAGGNLDDDPDPVSIIYELLPNPGRSAAQPKSRLVTIKEGSREETKVRGYYGFTFELSGPSELLELAVLAGVGRYNAEGFGAVGVK
>NZ_CP025096.1|WP_100992412.1|7339530_7340511_+|WYL-domain-containing-protein
MPVSQSQRFQRINDQLRRGAAIPTAELMQVCGVAERTLKEDINQMRDRYRAPIKFSRRLGGYHYYESFDLKTIEIELTNQDVAALKNAVTTLNQFRDLAVFADFRGAVEKIEQAVRFRISQPSTSQAYIAFEAVPPGQGNELLDELLVACMNRQVIEFKYQKYDDAAPRLRTVFPHLMKEHRNRWYIIGYELYPPQLRVFGLDRVIADSLKSTALSIDPPPFDAEAYFRPALGVAVYDDPAEDVILSFTQKAGLHFRAQPFYPFRKEDILVDSKDEFRVKLCIIINQELVFELARFGNSVKIMAPDSLVQKLITFLQSTLNQYQLY

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Crispr_ID: NZ_CP025096_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_7

7627359-7627438

Orphan

Consensus_repeat	Method
CAAAGTGACATCGTGTCACTTTG	CRISPRCasFinder

1 spacers

PD-DExK

The CRISPR arrays of NZ_CP025096_7

>merge|NZ_CP025096|7|7627359-7627438|CRISPRCasFinder
CAAAGTGACATCGTGTCACTTTGCTCCGCCCCGAGCGCTTAATAGAACTGCTTAGACCAAAGTGACATCGTGTCACTTTG

>NZ_CP025096|7|7|7627359-7627438|CRISPRCasFinder
CAAAGTGACATCGTGTCACTTTG	CTCCGCCCCGAGCGCTTAATAGAACTGCTTAGAC
CAAAGTGACATCGTGTCACTTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100992402.1\|7623000_7623231_+\|transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP025096.1\|WP_170069514.1\|7625667_7626864_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271194
NZ_CP025096.1\|WP_100992643.1\|7620598_7621066_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP025096.1\|WP_157816118.1\|7637278_7638304_-\|DUF3500-domain-containing-protein	unknown	unknown	gnl\|CDD\|378789
NZ_CP025096.1\|WP_100992642.1\|7619436_7620327_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187578
NZ_CP025096.1\|WP_100992649.1\|7624939_7625530_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP025096.1\|WP_100992652.1\|7628301_7629246_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NZ_CP025096.1\|WP_157816116.1\|7633286_7633460_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992658.1\|7635306_7636641_-\|HupE/UreJ-family-protein	unknown	unknown	gnl\|CDD\|379373
NZ_CP025096.1\|WP_100992647.1\|7623372_7623684_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992654.1\|7631614_7632544_-\|DUF1016-family-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl\|CDD\|380007
NZ_CP025096.1\|WP_100992648.1\|7623813_7624095_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992657.1\|7634436_7634706_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992653.1\|7629362_7630739_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP025096.1\|WP_157816115.1\|7632841_7633000_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100992656.1\|7634028_7634433_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237177
NZ_CP025096.1\|WP_100992646.1\|7622726_7622954_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP025096.1\|WP_157816113.1\|7621624_7622593_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816117.1\|7636716_7637325_-\|DUF3500-domain-containing-protein	unknown	unknown	gnl\|CDD\|378789
NZ_CP025096.1\|WP_100992644.1\|7621293_7621560_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100992402.1\|7623000_7623231_+\|transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.11997e-18
NZ_CP025096.1\|WP_170069514.1\|7625667_7626864_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271194	cd01194, INT_C_like_4, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	1.02843e-30
NZ_CP025096.1\|WP_157816118.1\|7637278_7638304_-\|DUF3500-domain-containing-protein	gnl\|CDD\|378789	pfam12006, DUF3500, Protein of unknown function (DUF3500). This family of proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 335 to 438 amino acids in length. This protein has a conserved GHH sequence motif. This protein has two completely conserved G residues that may be functionally important.	2.47312e-21
NZ_CP025096.1\|WP_100992642.1\|7619436_7620327_+\|SDR-family-oxidoreductase	gnl\|CDD\|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.26488e-71
NZ_CP025096.1\|WP_100992649.1\|7624939_7625530_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	6.39627e-56
NZ_CP025096.1\|WP_100992652.1\|7628301_7629246_-\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	1.12437e-56
NZ_CP025096.1\|WP_100992643.1\|7620598_7621066_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.39687e-18
NZ_CP025096.1\|WP_100992654.1\|7631614_7632544_-\|DUF1016-family-protein	gnl\|CDD\|380007	pfam17761, DUF1016_N, DUF1016 N-terminal domain. This family may include an HTH domain.	3.27754e-36
NZ_CP025096.1\|WP_100992656.1\|7634028_7634433_-\|hypothetical-protein	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0.0024379
NZ_CP025096.1\|WP_100992658.1\|7635306_7636641_-\|HupE/UreJ-family-protein	gnl\|CDD\|379373	pfam13795, HupE_UreJ_2, HupE / UreJ protein. These proteins contain many conserved histidines that may be involved in nickel binding.	2.28206e-51
NZ_CP025096.1\|WP_100992646.1\|7622726_7622954_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	1.58995e-09
NZ_CP025096.1\|WP_157816117.1\|7636716_7637325_-\|DUF3500-domain-containing-protein	gnl\|CDD\|378789	pfam12006, DUF3500, Protein of unknown function (DUF3500). This family of proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 335 to 438 amino acids in length. This protein has a conserved GHH sequence motif. This protein has two completely conserved G residues that may be functionally important.	2.0905e-37
NZ_CP025096.1\|WP_100992653.1\|7629362_7630739_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	8.11145e-39

>NZ_CP025096.1|WP_170069514.1|7625667_7626864_+|tyrosine-type-recombinase/integrase
MAQTPDPDNRQQAIGKTITRYTLSQLIRYFAANLPKSSNYPRHARSYVEFCLKHQFGIDGFSFTRYTAELPPNRVSPIRKFLLFYQTIGSPVILVDPKTTKIPPAANELVLRFIREAKSLRGDRSKETYTKALNAFFVYLDQQLALGQPASLGGLTVSDFVQQLKDQQYSAFTINLYLSAVKQLAAWSIRRRTDLQLNEDQLNALRDIHDVRGLAIERTFYKDSLEVDERQLVLGDVESSRDRAVLALLGLEGLRTVEVTRLKLGDLDFNRQQLLVLGKGKGTKKAIKFFASCRHILQTYLEETSRWPIANDQRSEYLFETLKTYQIRYIVDKQLKKHGLKRTGMSAHSLRHTAGQLLLDEGVSLEHVQQHLRHETLETTQFYTKKKTLKTYFQQMPD
>NZ_CP025096.1|WP_100992649.1|7624939_7625530_+|recombinase-family-protein
MKLGYARVSTTDQNLFLQLDALKLAGCEKVYQEKTSGSRVERPELNKLLALIREGDTLVIWKLDRLGRSLTHLIDLVTDLEQRHIGLLSINDPVDTTTAQGRLVFRIFASLAEFEREVIRERTLAGLASARRRGKLLGRPKGLSKSAEQKARIAESLYKEATYSVEQIAAELNISKTTLYKYLRLRGIPIAGLPSL
>NZ_CP025096.1|WP_100992648.1|7623813_7624095_+|hypothetical-protein
MDAICGGLIAFLLGYLLCLVLASLDAQLGAKGEDNLGELYKQQLEQQASIQKQNQLIDQLVKDKIKLTNSEKRLSNQLNELRKQHERTLSALN
>NZ_CP025096.1|WP_100992647.1|7623372_7623684_-|hypothetical-protein
MDTPLTDTHINHDGELDPSRVLTRWCEAITGLFMYFNALHVRLTTHSTTDAYIGQCPVYQLVQLAKTMHEELARLEQDLDQPPRDTPATSQPAFNRLAAQPQS
>NZ_CP025096.1|WP_100992402.1|7623000_7623231_+|transposase
MSRKGNCWDNAVAESFFKTLKCEMVNHTYFATRAAARLATFEYIEGWYNRRRKHSVLNYRTPSQQESYFYTSSMAA
>NZ_CP025096.1|WP_100992646.1|7622726_7622954_+|transposase
MVKRRVFDEAFKEMAIELSYAKGSIQDAARELDIDPGRIRKWRQRHKKNDQMLPANTTLTDEQQQIRRLQRELKD
>NZ_CP025096.1|WP_157816113.1|7621624_7622593_-|hypothetical-protein
MRYGMCFDGSVVRGRGDDGRPLHFSNTWATGHKDQMEDNYRWGRQMGLTLFRDTVLWDESKHCPDYAWLDRLQNTSNGQIELALNHYGLPEWINEAMFWDGQAAELMYQQAYQIAHRYQGAFRSYNIGVELGIWTDWIAAPNNRQWPFGGRPWWEVYRQTSAITIAIARGLKAGDPACLTAMSEPWGWGDMPYPDQARPFATVLGQVDEVARQNNCLTWQQGQMGLLDIIGLNIYFEHDIAHMLVAARHLFAGKKIVVAETANIYRPDCHPPALWWAKFEALQEADLEVSWNPGFSMLTHELGEAMAGNLLSADGTQHWQKR
>NZ_CP025096.1|WP_100992644.1|7621293_7621560_+|hypothetical-protein
MALLNLPAINPRLQATKLLDYTAKSSFLKKGLWLLHNLGVVRILVGKASSWSTFRVYGSLKRIFQYIYNAELPFMASCATATLVFMNN
>NZ_CP025096.1|WP_100992643.1|7620598_7621066_+|MarR-family-transcriptional-regulator
MHLEIDFHFKSPADSPGYQLGQLTMLWQRKQKRVLDPLDLTQTQLVLLAALGWLSRTSDAVTQVDIATQSNADRMMVSKVLRTLEDKGFIHRKEHPTDTRAKTITLTDSGAVVLQQALREIEQADVAFFLLPETALTGFNQTMALLIDQNKDANQ
>NZ_CP025096.1|WP_100992642.1|7619436_7620327_+|SDR-family-oxidoreductase
MNDKLLITGASGDLGRRVVNRLKGKIALENLTVLVRDENSELAQQYQHAGIEVKMGDYAKPASLLNAFEGIDVLYFVSAGDDDQRAQLHQNVVKAAKQARIKHIIYTSAVWKNETDSSPLATLVDSHRQTENTIKASGLPYTLLKHNLYAEVIQMLIGDRSQLLKTKTIYLPTANGVTSFVAKDDLAEAETTILLNHQQYANRTLAFDGSEALTFAAIAQQVGAILNEPIAYSSPDVATFENQMSQLGLPHPVIELLKTFSIAIAQGEFDQQSTDLATVLGRPTRPLADFLAEAYR
>NZ_CP025096.1|WP_100992652.1|7628301_7629246_-|ParA-family-protein
MITQEKLVRFLRAKPALNLSQIEKEAGIPSKTLHKALSEQKGIPAKHLPALDEAVRRYGYSETLFDKAKVISVVNHKGGVGKTTTTINVGKALSLLGNRVLLVDMDSQGNLSQCFGIHVPDEQVIDALLGGTPLPMIEIANNLFLTPSDIRMAYRESELANAVGADRRLSLKLEEARDKFDYILIDCPPSLGICTTCSLVASNYCVVPIQPEASAYHGVESLFNRIAEVRTYINPTLTVKGIVFTMVHKNQSVHKSMMAHIRDTFHNFHIYEAIIEVSTVIKQSQVAKEDLFTYSAKSPSWQQYHHLATEIMTI
>NZ_CP025096.1|WP_100992653.1|7629362_7630739_-|replication-initiation-protein
MAKETKVRKRSDIGERTIARMKAGRNGIIEATYRMDVVEFRVFFTMLTMISPDDVTFCEYELRVADIIRLFSLNRDGRSYETIKEAAERLVNKTMIIYHTKEDGNRYRTVIPFLTSASSQIGDVKMESIRVTFHPELKPFLLQLRSEYLEFDVRNLARVQSQYSIRLYMMLRHQMNLKKSSIRYTVERLREVFEIGDKDYPLYGNFKQKVLVRACIDLNTTTNIRIDKMEEERSNRKVVAVVFHMSSQDLPLADQDNAIPTAKITSPEISTSKKTSTIVEVDDSTTSLLIDDIHKLVEKYVGREAVRKWLHQSSEAQVRVAIDYTLKQLKQGVSIKNVGGYLQKMVNTSLPLSFEKQTSTGTSVKNTTEQKAKAEAEQFSEETRLKALTDHKYQTALQELSMHPEWKESVTAHMQSGLFGKFYNQNISLLENIKNPVMYGPFFQSIERLKPDVFAGIE
>NZ_CP025096.1|WP_100992654.1|7631614_7632544_-|DUF1016-family-protein
MDTSSTTHLELFRYLRTLVDTVNQGRETYPKFALVEAYWHIGRIVVETEQAGTERADYGIHLIEQLSERLTVTFGPGYSLPNIWRFKQFYLAFPILSTNGRELPNLQQHLRIELCWSHYRTLMKLKNLQERAFYLNQAADQGWTVKLTQKLIRARYYFQTALGQDQLLENPKKISAAPPPLKEVATLSLRTRLASIKKTLLERHVGYAFVAQRQFISLDGKDNWIELVFFHIILQRFVLVQPGEVGPTSSAAMTRLLDAYFTKQPSAITKPPVGLVIDLQGRVNLHTASFETGLALEEQVLIPLVISYI
>NZ_CP025096.1|WP_157816115.1|7632841_7633000_+|hypothetical-protein
MPAGSNQFQPDSNEFQSGCMDTDTGLGGSMGLNPRAGSKKPTPRPRWRDPQG
>NZ_CP025096.1|WP_157816116.1|7633286_7633460_-|hypothetical-protein
MRTQHLAALARPRSSPSSMPQRLMRNARLQTMSCLHQYIISIRLISPPSREDSGLPR
>NZ_CP025096.1|WP_100992656.1|7634028_7634433_-|hypothetical-protein
MTQLQQDQQLALEKERVQREKLMKTAGEWQRHSTILQEAKTDLEQTIKTQQQTLARQQVDLAQLKAKNDVQTIENQKLQRESNAIKAELAALRQQALDVLEKLTALHDESPINYIPRQFWPLLDEFKASVEAKL
>NZ_CP025096.1|WP_100992657.1|7634436_7634706_-|hypothetical-protein
MATNATKTIAVRIPYDEYLRRLRDATEAKLSMSEYLHLKLSDGDRVVQAEAQLVALSQLVKQLKLEAQEQANLAHEQACQADQQRIDLR
>NZ_CP025096.1|WP_100992658.1|7635306_7636641_-|HupE/UreJ-family-protein
MINTFFPNSRLFSRWRLFLFFIMGAMVALGPDVFAHQTPSTIVILDVSPTKVAVELQLPLGELELAFGHDVYKNPDNLVARVGPQLAEYLLAHIHPMVAKDQPWLVDVTDMHVEAAEQTYSGPYQEITVHLIMTPPTGASTRKFIFDYDVIMHQLVTHSALVSIRNDWERGKTDDQPAEVGVIRVDTKTTLIYPLLINLDQGSLWQGFRGMVSLGIEHIAEGTDHLLFLLVLLLPAPLLAEKKRWTGFGGWRYSLIRLLKVVTAFTLGHSLTLLLGALGWVNVPVQPVEILIAFSILVSAIHAWRPLFPGRETYIAASFGLVHGLAFASTLANLNLAPGQMALSILGFNIGIELMQLLVVALTVPWLMLLSQTRVYPFVRTAGAVLAGVAALAWLSERTFGQSNFLTALITKGAGYAPWLIIVLVSASLLLFWRERRQRKMITE
>NZ_CP025096.1|WP_157816117.1|7636716_7637325_-|DUF3500-domain-containing-protein
MLQFGGHHYAQSVTYEAGAVVSTTPSHQGIEPKSWTSGGVTYAPLAQEVAGMAAMLALFTTAELASAKISSTFSDVTMVPGSTTNTFPTTKLGVKVSTLSATAQANVIAAMAPWLNDLDDATAATFKALYANELANTYVTYASNTSGKSGDASSFFTTNTDYVRIDGPSVWIEFICQTGVVYRDQIHYHSVYRDHTRDYIGL
>NZ_CP025096.1|WP_157816118.1|7637278_7638304_-|DUF3500-domain-containing-protein
MKNRINNLVVLVGCFLLLVVSCKKTDDSVTTIAPTISSFSPTTGVVGATVTIIGTNFSTTAASNTVKFNGVAATVTAATATALTVTVPTGATTGTIIVTVDGQTATSSTSFTVTTTSTTTSPTITTFSPTSGAVGTAVVITGTNFSTTPASNTVTFNGVAATVSTATGTSLTVAVPAGATTGKLVVTVGTNTVASTSDFTVSTTGTTATPAQVVALANAFLATLSTTQQATVVLALNLTNAKKWSNLPCGVSCRNGLAFSTLSATQLAAAKAVIQAASGTVANEGYSEFIQIDAADDVLATTGGSGYSSGNYIIAFFGNAQFNGQMDATIWRAPLCPKCYL

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Crispr_ID: NZ_CP025096_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_8

8200927-8201034

Orphan

Consensus_repeat	Method
TCTAAAACCGTACAAAAACCTCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025096_8

>merge|NZ_CP025096|8|8200927-8201034|CRISPRCasFinder
TCTAAAACCGTACAAAAACCTCGTTATTTTTGTAAATAAACTTATAAATAAATGGCCAACTAACTGTTTAATAGATAGTTAACTCTAAAACCGTACAAAAACCTCGTG

>NZ_CP025096|8|8|8200927-8201034|CRISPRCasFinder
TCTAAAACCGTACAAAAACCTCGT	TATTTTTGTAAATAAACTTATAAATAAATGGCCAACTAACTGTTTAATAGATAGTTAAC
TCTAAAACCGTACAAAAACCTCGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100993102.1\|8204303_8207210_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226702
NZ_CP025096.1\|WP_100993108.1\|8211969_8212425_-\|arsenate-reductase-ArsC	unknown	unknown	gnl\|CDD\|319973
NZ_CP025096.1\|WP_100993101.1\|8202987_8203716_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993109.1\|8212446_8213310_-\|arsenite-methyltransferase	unknown	unknown	gnl\|CDD\|237007
NZ_CP025096.1\|WP_100993107.1\|8211516_8211966_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224167
NZ_CP025096.1\|WP_100993095.1\|8196712_8197267_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993106.1\|8210455_8211520_-\|ACR3-family-arsenite-efflux-transporter	unknown	unknown	gnl\|CDD\|213563
NZ_CP025096.1\|WP_100993098.1\|8199078_8199336_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379154
NZ_CP025096.1\|WP_157816155.1\|8201474_8202332_+\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP025096.1\|WP_100993091.1\|8191629_8192619_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|274884
NZ_CP025096.1\|WP_100993093.1\|8193971_8195222_+\|metabolite-traffic-protein-EboE	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993096.1\|8197412_8197925_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993103.1\|8207656_8208769_+\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP025096.1\|WP_100993092.1\|8192754_8193936_+\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|235740
NZ_CP025096.1\|WP_100993099.1\|8199409_8200363_+\|gliding-motility-associated-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|372639
NZ_CP025096.1\|WP_100993090.1\|8190558_8191311_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187604
NZ_CP025096.1\|WP_100993104.1\|8209011_8209620_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993094.1\|8195284_8196673_+\|alkaline-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366747
NZ_CP025096.1\|WP_100993097.1\|8198172_8198490_+\|LytTR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197918
NZ_CP025096.1\|WP_100993105.1\|8209655_8210459_-\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|378975

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993108.1\|8211969_8212425_-\|arsenate-reductase-ArsC	gnl\|CDD\|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	1.82091e-71
NZ_CP025096.1\|WP_100993109.1\|8212446_8213310_-\|arsenite-methyltransferase	gnl\|CDD\|237007	PRK11873, arsM, arsenite methyltransferase.	3.29047e-136
NZ_CP025096.1\|WP_100993107.1\|8211516_8211966_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224167	COG1246, ArgA, N-acetylglutamate synthase and related acetyltransferases [Amino acid transport and metabolism].	1.24212e-20
NZ_CP025096.1\|WP_100993092.1\|8192754_8193936_+\|3-dehydroquinate-synthase	gnl\|CDD\|235740	PRK06203, aroB, 3-dehydroquinate synthase; Reviewed.	0
NZ_CP025096.1\|WP_100993106.1\|8210455_8211520_-\|ACR3-family-arsenite-efflux-transporter	gnl\|CDD\|213563	TIGR00832, Uncharacterized_transporter_slr0944, arsenical-resistance protein. The Arsenical Resistance-3 (ACR3) Family (TC 2.A.59) The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport. [Cellular processes, Detoxification, Transport and binding proteins, Anions].	2.29611e-148
NZ_CP025096.1\|WP_100993098.1\|8199078_8199336_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379154	pfam13384, HTH_23, Homeodomain-like domain.	2.51203e-09
NZ_CP025096.1\|WP_157816155.1\|8201474_8202332_+\|RepB-family-plasmid-replication-initiator-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	1.45765e-42
NZ_CP025096.1\|WP_100993091.1\|8191629_8192619_+\|glycosyltransferase	gnl\|CDD\|274884	TIGR03965, glycosyltransferase_Rv0696_family, mycofactocin system glycosyltransferase. Members of this protein family are putative glycosyltransferases, members of pfam00535 (glycosyl transferase family 2). Members appear mostly in the Actinobacteria, where they appear to be part of a system for converting a precursor peptide (TIGR03969) into a novel redox carrier designated mycofactocin. A radical SAM enzyme, TIGR03962, is a proposed to be a key maturase for mycofactocin.	1.1698e-30
NZ_CP025096.1\|WP_100993103.1\|8207656_8208769_+\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	8.02916e-26
NZ_CP025096.1\|WP_100993102.1\|8204303_8207210_+\|PAS-domain-containing-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	7.46483e-56
NZ_CP025096.1\|WP_100993099.1\|8199409_8200363_+\|gliding-motility-associated-C-terminal-domain-containing-protein	gnl\|CDD\|372639	pfam13585, CHU_C, C-terminal domain of CHU protein family. The function of this C-terminal domain is not known; there are several conserved tryptophan and asparagine residues.	2.26459e-20
NZ_CP025096.1\|WP_100993090.1\|8190558_8191311_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187604	cd05346, SDR_c5, classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.95863e-114
NZ_CP025096.1\|WP_100993094.1\|8195284_8196673_+\|alkaline-phosphatase-family-protein	gnl\|CDD\|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	4.33527e-59
NZ_CP025096.1\|WP_100993097.1\|8198172_8198490_+\|LytTR-family-transcriptional-regulator	gnl\|CDD\|197918	smart00850, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.	2.42014e-08
NZ_CP025096.1\|WP_100993105.1\|8209655_8210459_-\|metallophosphoesterase-family-protein	gnl\|CDD\|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	4.80894e-17

>NZ_CP025096.1|WP_100993099.1|8199409_8200363_+|gliding-motility-associated-C-terminal-domain-containing-protein
MVTGRNPVCDKTNGALTIVARSNSEPLAYSIDGIHFRSTPDFEELQAGDYLVQVRDVNNCLVTSKVTLVQLSSPVIQNVEVLATTCGQANGSLTITALGTTNPLLYSIDSLTFQENPAFTNLKASTYRIYIKDGNGCTVDRNAQVLASSAPRIDQLLSESAACGANTGRLTVVADGQGTLTYSLNGGVFQEQPLFYDLSKGEYEVEVRDGQQCLQRQAVTISEECESEVYVPDAFSPNYDGVNDTWEIKSRVLEDIIINIYNKWGEKIFYSKQGQRQYWDGTYKGDLVSPGVYTYQMEWHAQNGIRNIKKGILVLIR
>NZ_CP025096.1|WP_100993098.1|8199078_8199336_-|helix-turn-helix-domain-containing-protein
MSRKEKHIDLNESEQITLREGAKYHPKPEFREKCRALLLNQAGVTIKQIATHLDVNHNTVGTWINTWETAGIVGLNRKLGQGRNP
>NZ_CP025096.1|WP_100993097.1|8198172_8198490_+|LytTR-family-transcriptional-regulator
MRHSALGNQAGRITHLIGEGNYTRIYFTDAPTLLISRTLSYCTAQLPHFVRLHRMCAANPDYINEIRPIPNKRGEALIAGAWLPVSNRRLPDAIRQLKAIKSKAV
>NZ_CP025096.1|WP_100993096.1|8197412_8197925_+|hypothetical-protein
MPLFALLKRYYRTPLFIAIGLFFSLLALAQTNLKYRLLNGYLLHADAPVNKGKPTLFVFEQAATFSQIFDPATNGSFRKRDAPNFDKEMAIGIVLSSTKTPPKLSVSRVFVQDSTLTVRYIRLADTTVTKSPLPEATQPMLVFTIPKQTVLKTRLVENGKVVQTLKKRDD
>NZ_CP025096.1|WP_100993095.1|8196712_8197267_+|hypothetical-protein
MKALVALFLLASACATHRTPVGNAPADGAEYYLPNQPVTAVLPRLYPDPQGGLGHSQDPDIRVTDIRLTASYTVLYITFGKDKNARDNNYFGTSNISFNPKAILTSSDGKRTYALLKTEGIPMSPDTREIKNEEKVPFILYFERLEKGVESFDLFECKSDNQNSCFNVAGMTVQNPQNSEAKQP
>NZ_CP025096.1|WP_100993094.1|8195284_8196673_+|alkaline-phosphatase-family-protein
MKKTVVLDVVGLSYSLIGEHTPFLKQWFASKHQATIDPMLPALTTSVQSTYVTGKWPSETGIVGNGWYDRTDSEVKFWKQSNKLVAGEKIWERAKQIDPAFTVSKMFWWYNMYSSADYSATPRPQYPSDGMKIADCYTQPADLRDRLQQELGTFPLFQFWGPATTIKSSRWIADASMLVDKWHNPTLTLIYLPHLDYCLQKSGQDFSKIANDLREIDDVCRDLIQYYEKQGAEVIVLSEYGITSVSKPIHINRILREAGMIRYREERGLEVFDAGASPAFATPDHQIAHVYINDASVFDKVRALLEKTPGIELVLDKEQQKKYHIDHERSGDLVVVADADSWFTYYYWLDDARAPDYARLVAIHQKPGYDPAEMFMDQTNPLIKLKAGYKLGRKLLGFRYLMNVISLDATLVKGSHGRLGAAPEYHPVFVSSQNVGKTLSAIDVYDKIWETLSIEIPAKQTS
>NZ_CP025096.1|WP_100993093.1|8193971_8195222_+|metabolite-traffic-protein-EboE
MKTLIGHLGYCTNIHPGETWTDHFAALQQAVPELKQRLSPNQAFGLGLRLSNIASEELEIPENLIAFQHWLAQNDCYVFTMNGFPFGGFHDTVVKDQVHTPDWTTEARVEYTKRLFRILSVLLPVDELGNPIQGGVSTSPLSYRHWFEWEQPAARDYILSQTTQNILEVVADLIRLHHQTDRLMHLDLEPEPDGVIETADEFISWFTDYLLPMGIEQLTEEFRLTDEEAEAAICEHVRLCYDVCHFAVDYERPAEVLDKLKNYGLRVGKIQISAALKAEFPTDPEERETVRQAFEEFNEPTYLHQVVARTNYGELLRFPDLPEALAALNDTHAEWRAHFHVPLFVSDYGVLKSTQDDIREVLRLQSDRMFTNQLEVETYTWGVLPNELKKELVDSIEREMKWVQQFSSNTTSETDS
>NZ_CP025096.1|WP_100993092.1|8192754_8193936_+|3-dehydroquinate-synthase
MDHLHQTFSVRFTYSVYFTEQLFDSTNSLLADFFSQQATAETRKKLLVVIDSGVVSTHPNLPATITSYFSQHADSVELVTDFLILPGGEIAKNDPDSVEKIVDAVDRHGIDRHSYVAAIGGGSVLDLVGYAAAISHRGIRHIRIPTTVLSQNDSGVGVKNGVNYKGKKNFLGTFVPPVAVFNDSQFLTTLDERDWRAGVSEAVKVALIKDKAFFEWIEQNAEALAARDMTAMQYLVHRCADMHLQHIAGGDPFEMGSSRPLDFGHWSAHKLEQLTNFEIRHGEAVAIGIAMDSLYSQQLGWLSETDTNRILTTLRTLGFVLYQPMLDADNSAGVLKGLSEFREHLGGQLTIMLLKDLGRGVEVHEMDADRIRQAIATLREQESLTLQPALSGQ
>NZ_CP025096.1|WP_100993091.1|8191629_8192619_+|glycosyltransferase
MLPAFSVVIPTYKQPALLLKCLDALGRQRLAHDQFEIIVVDEGNSPETEAAVLLFAKQIARDSARIEVRYLGQPERRGSAAARNRGWRAARGHLIAFTDDDCLPEPTWLSSALTCFQRGAQVLSGQLRVLLPNQPTPLDRTATFLKRAEFIASNCFCRKATLERVGGFEEAFDIDWREDSDLQFKFIQAGIPIGKCPEAIVVYPIRPYPWYGLLQDERNNSYDALLYKRHPGLFRERIPSYRRQILRYYASVISIVIALIGGFTGQVNIAITGLLIWAILSADLVVHRLPNSPLTWLTLKHAVLMALATPFLSVYWRLYGAIKYRVLYL
>NZ_CP025096.1|WP_100993090.1|8190558_8191311_-|SDR-family-NAD(P)-dependent-oxidoreductase
MSRIALITGATSGIGRATAKAFADLSYRLILCGRRQDRLSELTDELGGQTTVTTLNFDVRDWADVNDAISTLPDEWKAIDILVNSAGNAHGMSAIQDGEPADWDQMIDGNVQGLLYVSKAVMPGMVSRQRGHIVNLSSVAGKQTYANGAVYCASKAAVEALSTGMRLDLTQHGIKVTNIAPGAVETEFSVVRFKGDTERAAKVYEGFAPLTADDIADSIVYAVTAPANVTIADMTILASAQSAATTINRK
>NZ_CP025096.1|WP_157816155.1|8201474_8202332_+|RepB-family-plasmid-replication-initiator-protein
MSEILFQSNALTTAQYEMTALQKNIFYTVQSQLGADDLPGKEYLVRVRDIMSVTNTKNPYEDLRKATENMMQKIMTIAVPNGFIQVAPFSSVQYNTNEGTIAICIDSKLRPYLFNLENRITIFGYNEAMNIPGKYSKRLYEMLSQWKSMGLMKGTIVNLRAALKLEDKYPDWDNLKRRVLEPAVAEVNKHSDLFVKFYPERENRRIVLLKWTIKQKETHIITPTPSELEQKLISEFKLRPDQAKFVIENYEIVFIHRKLHEIVVKNASRRIQSMGAYTAKVFNVI
>NZ_CP025096.1|WP_100993101.1|8202987_8203716_+|hypothetical-protein
MAKKPTKREDEAPLAALRTVLKTQAIQLSPGINQISNPPPPDQHLEYYFIPMQFMTQYQAYNRPGKPLKNLKLVNYDKPAISLSFFYKHKYSIERQVIHGDVLQHIKNYRDDLLNRSLMEQLSVGQLKELRETDELLRRVRQEPDAYQACFSNYHHKYYYWYCTYRYFDDLASMKTTTSSEHLLKHTERVGHQVHERLNIIFIDPEYINESVPHDHKLIDRELKNYPIHLRQGITTLYLRER
>NZ_CP025096.1|WP_100993102.1|8204303_8207210_+|PAS-domain-containing-protein
MTGDQRPLDRSKQLTERLDINLALQAADLGVWEIDLPTNQVLLDQRCCQLFGITSHQLSFSDTLHHIHPDDVEGVNQAMQWALNPQSDGNYQVSYRSIGQDGRTHWIRSTGRRYLDQRGQPIRLAGVSQELTQQVEAQQQEAAALQQSEDRFRVLIEEAPVATCLFVGRQLVIEVANQAMIQVWGKGPDVIGLPLAEALPELKDQHFLTTLDELFTTGKTYQAKGGRADLVIEGQLQTFYFNYDFKPLRTPGGEVYAILETAQDVTEQVLAQQRVEQSQQQLLTLFEQSPVGLATISASDELVFQWANSFYGELVARPPQDIVGKPLLDALPELTGQGFDEILKNVIATGNPFVAPEVAVGILRDGQLTTIYVDLTYQPQKGALGAVEAILVVATDVTQQVVTRKQIEESESKLRAIVATAPAGIGVFVGRDLVIENPNQTFIDIVGKGPHIAGLPLREVMPELLTEVQPFLQILDDVFTTGNSFISPSSLVKIVQNGVLTDNYYNISYSPIRNAAGEVYAILDIAIDVTEAVIAQQQLKVSEAFAQNLLYNSPVANVVLLGEDMLIHSINEGMLAMLGRDNSIIGMPFIAAMPELEPTPLLGRLRQVLTTGEAFQQPEERFELVRYGQPHTGYYQYIYTALRDALDQPTGVVITAIEVTTQVLARQQVEASEARYRTLSEDLEQQVLQRTQELAATNEELAANNEELEASNEEYAALNEELEEANSLLIRSNDNLQTFAYVASHDLQEPLRKIQQFGDLLRQRSGSTLGDGLPYLERMQAAASRMSALIRDLLTFSRISTQRDTSGPVALPAVIQVVLTDLELVIDETGARIEVDDLPTLEGDRSQLEQLFQNLISNALKFRKPGVVPLVQIRSRWLAAEHLPPTIKPARRAVAYHQLEVIDNGIGFDEKYLDRIFQVFQRLHGKSEYAGTGIGLAICAKVVTNHGGAISARSQPGQGAAFTIYLPV
>NZ_CP025096.1|WP_100993103.1|8207656_8208769_+|acyltransferase
MNNNPFGTKPHYQLLDGLRGVAAMIVVCFHLTEPLASSHLDNIVNHGYLAVDFFFLLSGFVIGYAYDDRWGQLTIGGFLRRRFERLQPLVVLGMTLGALGFYFTDSTIWPLIHTVPVWKLIVVWLIGCTLVPIPLSMDIRGWQEMHPLNSVGWSLFFEYIANILYGLGLRKLSTKALTCFVVLTGAVLLHFAVTNLNGDVTGGWTLNGEHMRVGLTRTLFPFFAGLLLSRVARPVYINHAFVWCSGLVMAVLLMPRLGGADHLWVNGLYEAFCIILVFPLIVYIGASGVVHNQREAKICQFLGNLSYPLYMTHYVLVYFYVAWVSNHKGITLWQVWPYALLTFSGAIVLAYASLKWYDEPVRAWLRTKLK
>NZ_CP025096.1|WP_100993104.1|8209011_8209620_-|hypothetical-protein
MRKILCWFAIAGMLYFMAAPGLAQSSSHFLIDNTREGAWRYTSVRETPYQSNGRVIQHQLTTLGKKLNHLSVVDAPAYSQLQGELHGYLQRLENDSPDYGRVEVYHAVLLRLMQFEESIKEILVENRQRDSHLLAPDAIKPDEGQQAAVLPYALLFRRQDHRSKLVHIVTNEKVTVLKHGPTYCLVRCGPYEGYLHKGMIVR
>NZ_CP025096.1|WP_100993105.1|8209655_8210459_-|metallophosphoesterase-family-protein
MKIALFSDIHANLPALDAVLADIDSRQPDAVYCLGDLVGYNIWPNEVIRTIRKRGIPTIAGNYDYGIGRGSDDCGCAYKEEQEKANGKVSIAYTNAQVGNDERQYLRTLPTHSRVEFELGNDPEHLWQQQTPFTLLLVHGSPRRVNEYLFEDRGDRSLGRVIEGAGADVMCFGHTHKPFHKVVSAEAEGQETYWRHAINIGSVGKPKDGDPRAGYVLLTIDETARPGSREGVAVEFVRVAYDVEKAAQAVEQSELPDAYAEALRIAR
>NZ_CP025096.1|WP_100993106.1|8210455_8211520_-|ACR3-family-arsenite-efflux-transporter
MSVPRLSFLDRYLTLWIFLAMLIGVGIGYFFPQSQGFINQFNSGSTNIPLAIGLVLMMYPPLAKVRYSELPKVFANTKILGLSLFQNWIVGPLLMFGLAVVFLPDKPEYMTGLIMIGIARCIAMVIVWNDLAKGDRLYAAGLVAFNSIFQVLFYSVYAYVFITVLPPLFGLKGYTVNITIGEVAKSVFIYLGVPFLLGLFSRIILTRLFSRQWYEERFLPAISPITLIALLFTIVVMFSLKGQLIVSIPLDVVRIAIPLTIYFAIMFFSAFYLSKRAGADYGKSTSLAFTAAGNNFELGIAVAIAVFGINSGAAFAAVVGPLIEVPVLILMVNFALKQEKKFAPHYTKAFQKHA
>NZ_CP025096.1|WP_100993107.1|8211516_8211966_-|GNAT-family-N-acetyltransferase
MALYIEPAQLADKAAIIALLEQGHLLTEDLPTRLADFVIAKEEGRPIGVAGLERFGLVGLLRSVAVDPQYQGQQIAAQLVSRLMETAQASSLENVYLITNTADRYFERYGFQIVNRQEVPAAIQQTQQFSELCPSSAIVMKRALTQDQS
>NZ_CP025096.1|WP_100993108.1|8211969_8212425_-|arsenate-reductase-ArsC
MKKILVLCTGNSARSQMAEGYLQHFSGDRAQVYSAGVAPHCVNPLAIQVMAEDGIDISHHTSNHADEYVQIPFDYVITVCDNAREQCPYFPTAGEMIHHSFPDPGHTASAGTPERDRPGEDKLTSFRRVRDLIKTYSQEFIKSRLGEPVPQ
>NZ_CP025096.1|WP_100993109.1|8212446_8213310_-|arsenite-methyltransferase
METAEQIKEVVRQKYGAIAEQPEENSCCGPTSCCGPETVANVPIDMTVGYDELKGYVAEADLGLGCGLPTQFAQIKPGDTVVDLGSGAGNDCFVARAETGETGRVIGLDMTPAMIDRARKNTKTLGFTNVEFVYGDIEDMPLPSNLADVVVSNCVMNLVPDKQKAVAETFRILKPGGHFSISDIVLKGELPAGLQQDAELYVGCVSGAIQKADYLQLVQESGFTNITVRKEREISLPDDVLKNYLSVEEIADYRQQDKGIYSVTVFAQKPADAPTATASCCGPDCCN

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Crispr_ID: NZ_CP025096_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_9

8201236-8201369

Orphan

Consensus_repeat	Method
TCTAAAACCGTACAAAAACCTCGT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP025096_9

>merge|NZ_CP025096|9|8201236-8201369|CRISPRCasFinder
GGTATCCCCGTACAAAAACCTCGTCACTCCCGTACAAAAACCTCGCTATCTCCGTACAAAAACCTCGTAACATTTTGTCTCAAGTCCGTACACTAACCTAGTAGCCAATTTTTTATCCCGTACAAAAACCTCGT

>NZ_CP025096|9|9|8201236-8201369|CRISPRCasFinder
GGTATCCCCGTACAAAAACCTCGT	CACTCCCGTACAAAAACCTC
GCTATCTCCGTACAAAAACCTCGT	AACATTTTGTCTCAAGTCCGTACACTAACCTAGTAGCCAATT
TTTTATCCCGTACAAAAACCTCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100993102.1\|8204303_8207210_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226702
NZ_CP025096.1\|WP_100993108.1\|8211969_8212425_-\|arsenate-reductase-ArsC	unknown	unknown	gnl\|CDD\|319973
NZ_CP025096.1\|WP_100993101.1\|8202987_8203716_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993109.1\|8212446_8213310_-\|arsenite-methyltransferase	unknown	unknown	gnl\|CDD\|237007
NZ_CP025096.1\|WP_100993107.1\|8211516_8211966_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224167
NZ_CP025096.1\|WP_100993095.1\|8196712_8197267_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993106.1\|8210455_8211520_-\|ACR3-family-arsenite-efflux-transporter	unknown	unknown	gnl\|CDD\|213563
NZ_CP025096.1\|WP_100993098.1\|8199078_8199336_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379154
NZ_CP025096.1\|WP_157816155.1\|8201474_8202332_+\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP025096.1\|WP_100993091.1\|8191629_8192619_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|274884
NZ_CP025096.1\|WP_100993093.1\|8193971_8195222_+\|metabolite-traffic-protein-EboE	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993096.1\|8197412_8197925_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993103.1\|8207656_8208769_+\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP025096.1\|WP_100993092.1\|8192754_8193936_+\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|235740
NZ_CP025096.1\|WP_100993099.1\|8199409_8200363_+\|gliding-motility-associated-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|372639
NZ_CP025096.1\|WP_100993090.1\|8190558_8191311_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187604
NZ_CP025096.1\|WP_100993104.1\|8209011_8209620_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993094.1\|8195284_8196673_+\|alkaline-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366747
NZ_CP025096.1\|WP_100993097.1\|8198172_8198490_+\|LytTR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197918
NZ_CP025096.1\|WP_100993105.1\|8209655_8210459_-\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|378975

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993108.1\|8211969_8212425_-\|arsenate-reductase-ArsC	gnl\|CDD\|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	1.82091e-71
NZ_CP025096.1\|WP_100993109.1\|8212446_8213310_-\|arsenite-methyltransferase	gnl\|CDD\|237007	PRK11873, arsM, arsenite methyltransferase.	3.29047e-136
NZ_CP025096.1\|WP_100993107.1\|8211516_8211966_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224167	COG1246, ArgA, N-acetylglutamate synthase and related acetyltransferases [Amino acid transport and metabolism].	1.24212e-20
NZ_CP025096.1\|WP_100993092.1\|8192754_8193936_+\|3-dehydroquinate-synthase	gnl\|CDD\|235740	PRK06203, aroB, 3-dehydroquinate synthase; Reviewed.	0
NZ_CP025096.1\|WP_100993106.1\|8210455_8211520_-\|ACR3-family-arsenite-efflux-transporter	gnl\|CDD\|213563	TIGR00832, Uncharacterized_transporter_slr0944, arsenical-resistance protein. The Arsenical Resistance-3 (ACR3) Family (TC 2.A.59) The first protein of the ACR3 family functionally characterized was the ACR3 protein of Saccharomyces cerevisiae. It is present in the yeast plasma membrane and pumps arsenite out of the cell in response to the pmf. Similar proteins are found in bacteria, often as part of a four gene operon with an regulatory protein ArsR, a protein of unknown function ArsH, and an arsenate reductase that converts arsenate to arsenite to facilitate transport. [Cellular processes, Detoxification, Transport and binding proteins, Anions].	2.29611e-148
NZ_CP025096.1\|WP_100993098.1\|8199078_8199336_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379154	pfam13384, HTH_23, Homeodomain-like domain.	2.51203e-09
NZ_CP025096.1\|WP_157816155.1\|8201474_8202332_+\|RepB-family-plasmid-replication-initiator-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	1.45765e-42
NZ_CP025096.1\|WP_100993091.1\|8191629_8192619_+\|glycosyltransferase	gnl\|CDD\|274884	TIGR03965, glycosyltransferase_Rv0696_family, mycofactocin system glycosyltransferase. Members of this protein family are putative glycosyltransferases, members of pfam00535 (glycosyl transferase family 2). Members appear mostly in the Actinobacteria, where they appear to be part of a system for converting a precursor peptide (TIGR03969) into a novel redox carrier designated mycofactocin. A radical SAM enzyme, TIGR03962, is a proposed to be a key maturase for mycofactocin.	1.1698e-30
NZ_CP025096.1\|WP_100993103.1\|8207656_8208769_+\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	8.02916e-26
NZ_CP025096.1\|WP_100993102.1\|8204303_8207210_+\|PAS-domain-containing-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	7.46483e-56
NZ_CP025096.1\|WP_100993099.1\|8199409_8200363_+\|gliding-motility-associated-C-terminal-domain-containing-protein	gnl\|CDD\|372639	pfam13585, CHU_C, C-terminal domain of CHU protein family. The function of this C-terminal domain is not known; there are several conserved tryptophan and asparagine residues.	2.26459e-20
NZ_CP025096.1\|WP_100993090.1\|8190558_8191311_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187604	cd05346, SDR_c5, classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.95863e-114
NZ_CP025096.1\|WP_100993094.1\|8195284_8196673_+\|alkaline-phosphatase-family-protein	gnl\|CDD\|366747	pfam01663, Phosphodiest, Type I phosphodiesterase / nucleotide pyrophosphatase. This family consists of phosphodiesterases, including human plasma-cell membrane glycoprotein PC-1 / alkaline phosphodiesterase i / nucleotide pyrophosphatase (nppase). These enzymes catalyze the cleavage of phosphodiester and phosphosulfate bonds in NAD, deoxynucleotides and nucleotide sugars. Also in this family is ATX an autotaxin, tumor cell motility-stimulating protein which exhibits type I phosphodiesterases activity. The alignment encompasses the active site. Also present with in this family is 60-kDa Ca2+-ATPase form F. odoratum.	4.33527e-59
NZ_CP025096.1\|WP_100993097.1\|8198172_8198490_+\|LytTR-family-transcriptional-regulator	gnl\|CDD\|197918	smart00850, LytTR, LytTr DNA-binding domain. This domain is found in a variety of bacterial transcriptional regulators. The domain binds to a specific DNA sequence pattern.	2.42014e-08
NZ_CP025096.1\|WP_100993105.1\|8209655_8210459_-\|metallophosphoesterase-family-protein	gnl\|CDD\|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	4.80894e-17

>NZ_CP025096.1|WP_100993099.1|8199409_8200363_+|gliding-motility-associated-C-terminal-domain-containing-protein
MVTGRNPVCDKTNGALTIVARSNSEPLAYSIDGIHFRSTPDFEELQAGDYLVQVRDVNNCLVTSKVTLVQLSSPVIQNVEVLATTCGQANGSLTITALGTTNPLLYSIDSLTFQENPAFTNLKASTYRIYIKDGNGCTVDRNAQVLASSAPRIDQLLSESAACGANTGRLTVVADGQGTLTYSLNGGVFQEQPLFYDLSKGEYEVEVRDGQQCLQRQAVTISEECESEVYVPDAFSPNYDGVNDTWEIKSRVLEDIIINIYNKWGEKIFYSKQGQRQYWDGTYKGDLVSPGVYTYQMEWHAQNGIRNIKKGILVLIR
>NZ_CP025096.1|WP_100993098.1|8199078_8199336_-|helix-turn-helix-domain-containing-protein
MSRKEKHIDLNESEQITLREGAKYHPKPEFREKCRALLLNQAGVTIKQIATHLDVNHNTVGTWINTWETAGIVGLNRKLGQGRNP
>NZ_CP025096.1|WP_100993097.1|8198172_8198490_+|LytTR-family-transcriptional-regulator
MRHSALGNQAGRITHLIGEGNYTRIYFTDAPTLLISRTLSYCTAQLPHFVRLHRMCAANPDYINEIRPIPNKRGEALIAGAWLPVSNRRLPDAIRQLKAIKSKAV
>NZ_CP025096.1|WP_100993096.1|8197412_8197925_+|hypothetical-protein
MPLFALLKRYYRTPLFIAIGLFFSLLALAQTNLKYRLLNGYLLHADAPVNKGKPTLFVFEQAATFSQIFDPATNGSFRKRDAPNFDKEMAIGIVLSSTKTPPKLSVSRVFVQDSTLTVRYIRLADTTVTKSPLPEATQPMLVFTIPKQTVLKTRLVENGKVVQTLKKRDD
>NZ_CP025096.1|WP_100993095.1|8196712_8197267_+|hypothetical-protein
MKALVALFLLASACATHRTPVGNAPADGAEYYLPNQPVTAVLPRLYPDPQGGLGHSQDPDIRVTDIRLTASYTVLYITFGKDKNARDNNYFGTSNISFNPKAILTSSDGKRTYALLKTEGIPMSPDTREIKNEEKVPFILYFERLEKGVESFDLFECKSDNQNSCFNVAGMTVQNPQNSEAKQP
>NZ_CP025096.1|WP_100993094.1|8195284_8196673_+|alkaline-phosphatase-family-protein
MKKTVVLDVVGLSYSLIGEHTPFLKQWFASKHQATIDPMLPALTTSVQSTYVTGKWPSETGIVGNGWYDRTDSEVKFWKQSNKLVAGEKIWERAKQIDPAFTVSKMFWWYNMYSSADYSATPRPQYPSDGMKIADCYTQPADLRDRLQQELGTFPLFQFWGPATTIKSSRWIADASMLVDKWHNPTLTLIYLPHLDYCLQKSGQDFSKIANDLREIDDVCRDLIQYYEKQGAEVIVLSEYGITSVSKPIHINRILREAGMIRYREERGLEVFDAGASPAFATPDHQIAHVYINDASVFDKVRALLEKTPGIELVLDKEQQKKYHIDHERSGDLVVVADADSWFTYYYWLDDARAPDYARLVAIHQKPGYDPAEMFMDQTNPLIKLKAGYKLGRKLLGFRYLMNVISLDATLVKGSHGRLGAAPEYHPVFVSSQNVGKTLSAIDVYDKIWETLSIEIPAKQTS
>NZ_CP025096.1|WP_100993093.1|8193971_8195222_+|metabolite-traffic-protein-EboE
MKTLIGHLGYCTNIHPGETWTDHFAALQQAVPELKQRLSPNQAFGLGLRLSNIASEELEIPENLIAFQHWLAQNDCYVFTMNGFPFGGFHDTVVKDQVHTPDWTTEARVEYTKRLFRILSVLLPVDELGNPIQGGVSTSPLSYRHWFEWEQPAARDYILSQTTQNILEVVADLIRLHHQTDRLMHLDLEPEPDGVIETADEFISWFTDYLLPMGIEQLTEEFRLTDEEAEAAICEHVRLCYDVCHFAVDYERPAEVLDKLKNYGLRVGKIQISAALKAEFPTDPEERETVRQAFEEFNEPTYLHQVVARTNYGELLRFPDLPEALAALNDTHAEWRAHFHVPLFVSDYGVLKSTQDDIREVLRLQSDRMFTNQLEVETYTWGVLPNELKKELVDSIEREMKWVQQFSSNTTSETDS
>NZ_CP025096.1|WP_100993092.1|8192754_8193936_+|3-dehydroquinate-synthase
MDHLHQTFSVRFTYSVYFTEQLFDSTNSLLADFFSQQATAETRKKLLVVIDSGVVSTHPNLPATITSYFSQHADSVELVTDFLILPGGEIAKNDPDSVEKIVDAVDRHGIDRHSYVAAIGGGSVLDLVGYAAAISHRGIRHIRIPTTVLSQNDSGVGVKNGVNYKGKKNFLGTFVPPVAVFNDSQFLTTLDERDWRAGVSEAVKVALIKDKAFFEWIEQNAEALAARDMTAMQYLVHRCADMHLQHIAGGDPFEMGSSRPLDFGHWSAHKLEQLTNFEIRHGEAVAIGIAMDSLYSQQLGWLSETDTNRILTTLRTLGFVLYQPMLDADNSAGVLKGLSEFREHLGGQLTIMLLKDLGRGVEVHEMDADRIRQAIATLREQESLTLQPALSGQ
>NZ_CP025096.1|WP_100993091.1|8191629_8192619_+|glycosyltransferase
MLPAFSVVIPTYKQPALLLKCLDALGRQRLAHDQFEIIVVDEGNSPETEAAVLLFAKQIARDSARIEVRYLGQPERRGSAAARNRGWRAARGHLIAFTDDDCLPEPTWLSSALTCFQRGAQVLSGQLRVLLPNQPTPLDRTATFLKRAEFIASNCFCRKATLERVGGFEEAFDIDWREDSDLQFKFIQAGIPIGKCPEAIVVYPIRPYPWYGLLQDERNNSYDALLYKRHPGLFRERIPSYRRQILRYYASVISIVIALIGGFTGQVNIAITGLLIWAILSADLVVHRLPNSPLTWLTLKHAVLMALATPFLSVYWRLYGAIKYRVLYL
>NZ_CP025096.1|WP_100993090.1|8190558_8191311_-|SDR-family-NAD(P)-dependent-oxidoreductase
MSRIALITGATSGIGRATAKAFADLSYRLILCGRRQDRLSELTDELGGQTTVTTLNFDVRDWADVNDAISTLPDEWKAIDILVNSAGNAHGMSAIQDGEPADWDQMIDGNVQGLLYVSKAVMPGMVSRQRGHIVNLSSVAGKQTYANGAVYCASKAAVEALSTGMRLDLTQHGIKVTNIAPGAVETEFSVVRFKGDTERAAKVYEGFAPLTADDIADSIVYAVTAPANVTIADMTILASAQSAATTINRK
>NZ_CP025096.1|WP_157816155.1|8201474_8202332_+|RepB-family-plasmid-replication-initiator-protein
MSEILFQSNALTTAQYEMTALQKNIFYTVQSQLGADDLPGKEYLVRVRDIMSVTNTKNPYEDLRKATENMMQKIMTIAVPNGFIQVAPFSSVQYNTNEGTIAICIDSKLRPYLFNLENRITIFGYNEAMNIPGKYSKRLYEMLSQWKSMGLMKGTIVNLRAALKLEDKYPDWDNLKRRVLEPAVAEVNKHSDLFVKFYPERENRRIVLLKWTIKQKETHIITPTPSELEQKLISEFKLRPDQAKFVIENYEIVFIHRKLHEIVVKNASRRIQSMGAYTAKVFNVI
>NZ_CP025096.1|WP_100993101.1|8202987_8203716_+|hypothetical-protein
MAKKPTKREDEAPLAALRTVLKTQAIQLSPGINQISNPPPPDQHLEYYFIPMQFMTQYQAYNRPGKPLKNLKLVNYDKPAISLSFFYKHKYSIERQVIHGDVLQHIKNYRDDLLNRSLMEQLSVGQLKELRETDELLRRVRQEPDAYQACFSNYHHKYYYWYCTYRYFDDLASMKTTTSSEHLLKHTERVGHQVHERLNIIFIDPEYINESVPHDHKLIDRELKNYPIHLRQGITTLYLRER
>NZ_CP025096.1|WP_100993102.1|8204303_8207210_+|PAS-domain-containing-protein
MTGDQRPLDRSKQLTERLDINLALQAADLGVWEIDLPTNQVLLDQRCCQLFGITSHQLSFSDTLHHIHPDDVEGVNQAMQWALNPQSDGNYQVSYRSIGQDGRTHWIRSTGRRYLDQRGQPIRLAGVSQELTQQVEAQQQEAAALQQSEDRFRVLIEEAPVATCLFVGRQLVIEVANQAMIQVWGKGPDVIGLPLAEALPELKDQHFLTTLDELFTTGKTYQAKGGRADLVIEGQLQTFYFNYDFKPLRTPGGEVYAILETAQDVTEQVLAQQRVEQSQQQLLTLFEQSPVGLATISASDELVFQWANSFYGELVARPPQDIVGKPLLDALPELTGQGFDEILKNVIATGNPFVAPEVAVGILRDGQLTTIYVDLTYQPQKGALGAVEAILVVATDVTQQVVTRKQIEESESKLRAIVATAPAGIGVFVGRDLVIENPNQTFIDIVGKGPHIAGLPLREVMPELLTEVQPFLQILDDVFTTGNSFISPSSLVKIVQNGVLTDNYYNISYSPIRNAAGEVYAILDIAIDVTEAVIAQQQLKVSEAFAQNLLYNSPVANVVLLGEDMLIHSINEGMLAMLGRDNSIIGMPFIAAMPELEPTPLLGRLRQVLTTGEAFQQPEERFELVRYGQPHTGYYQYIYTALRDALDQPTGVVITAIEVTTQVLARQQVEASEARYRTLSEDLEQQVLQRTQELAATNEELAANNEELEASNEEYAALNEELEEANSLLIRSNDNLQTFAYVASHDLQEPLRKIQQFGDLLRQRSGSTLGDGLPYLERMQAAASRMSALIRDLLTFSRISTQRDTSGPVALPAVIQVVLTDLELVIDETGARIEVDDLPTLEGDRSQLEQLFQNLISNALKFRKPGVVPLVQIRSRWLAAEHLPPTIKPARRAVAYHQLEVIDNGIGFDEKYLDRIFQVFQRLHGKSEYAGTGIGLAICAKVVTNHGGAISARSQPGQGAAFTIYLPV
>NZ_CP025096.1|WP_100993103.1|8207656_8208769_+|acyltransferase
MNNNPFGTKPHYQLLDGLRGVAAMIVVCFHLTEPLASSHLDNIVNHGYLAVDFFFLLSGFVIGYAYDDRWGQLTIGGFLRRRFERLQPLVVLGMTLGALGFYFTDSTIWPLIHTVPVWKLIVVWLIGCTLVPIPLSMDIRGWQEMHPLNSVGWSLFFEYIANILYGLGLRKLSTKALTCFVVLTGAVLLHFAVTNLNGDVTGGWTLNGEHMRVGLTRTLFPFFAGLLLSRVARPVYINHAFVWCSGLVMAVLLMPRLGGADHLWVNGLYEAFCIILVFPLIVYIGASGVVHNQREAKICQFLGNLSYPLYMTHYVLVYFYVAWVSNHKGITLWQVWPYALLTFSGAIVLAYASLKWYDEPVRAWLRTKLK
>NZ_CP025096.1|WP_100993104.1|8209011_8209620_-|hypothetical-protein
MRKILCWFAIAGMLYFMAAPGLAQSSSHFLIDNTREGAWRYTSVRETPYQSNGRVIQHQLTTLGKKLNHLSVVDAPAYSQLQGELHGYLQRLENDSPDYGRVEVYHAVLLRLMQFEESIKEILVENRQRDSHLLAPDAIKPDEGQQAAVLPYALLFRRQDHRSKLVHIVTNEKVTVLKHGPTYCLVRCGPYEGYLHKGMIVR
>NZ_CP025096.1|WP_100993105.1|8209655_8210459_-|metallophosphoesterase-family-protein
MKIALFSDIHANLPALDAVLADIDSRQPDAVYCLGDLVGYNIWPNEVIRTIRKRGIPTIAGNYDYGIGRGSDDCGCAYKEEQEKANGKVSIAYTNAQVGNDERQYLRTLPTHSRVEFELGNDPEHLWQQQTPFTLLLVHGSPRRVNEYLFEDRGDRSLGRVIEGAGADVMCFGHTHKPFHKVVSAEAEGQETYWRHAINIGSVGKPKDGDPRAGYVLLTIDETARPGSREGVAVEFVRVAYDVEKAAQAVEQSELPDAYAEALRIAR
>NZ_CP025096.1|WP_100993106.1|8210455_8211520_-|ACR3-family-arsenite-efflux-transporter
MSVPRLSFLDRYLTLWIFLAMLIGVGIGYFFPQSQGFINQFNSGSTNIPLAIGLVLMMYPPLAKVRYSELPKVFANTKILGLSLFQNWIVGPLLMFGLAVVFLPDKPEYMTGLIMIGIARCIAMVIVWNDLAKGDRLYAAGLVAFNSIFQVLFYSVYAYVFITVLPPLFGLKGYTVNITIGEVAKSVFIYLGVPFLLGLFSRIILTRLFSRQWYEERFLPAISPITLIALLFTIVVMFSLKGQLIVSIPLDVVRIAIPLTIYFAIMFFSAFYLSKRAGADYGKSTSLAFTAAGNNFELGIAVAIAVFGINSGAAFAAVVGPLIEVPVLILMVNFALKQEKKFAPHYTKAFQKHA
>NZ_CP025096.1|WP_100993107.1|8211516_8211966_-|GNAT-family-N-acetyltransferase
MALYIEPAQLADKAAIIALLEQGHLLTEDLPTRLADFVIAKEEGRPIGVAGLERFGLVGLLRSVAVDPQYQGQQIAAQLVSRLMETAQASSLENVYLITNTADRYFERYGFQIVNRQEVPAAIQQTQQFSELCPSSAIVMKRALTQDQS
>NZ_CP025096.1|WP_100993108.1|8211969_8212425_-|arsenate-reductase-ArsC
MKKILVLCTGNSARSQMAEGYLQHFSGDRAQVYSAGVAPHCVNPLAIQVMAEDGIDISHHTSNHADEYVQIPFDYVITVCDNAREQCPYFPTAGEMIHHSFPDPGHTASAGTPERDRPGEDKLTSFRRVRDLIKTYSQEFIKSRLGEPVPQ
>NZ_CP025096.1|WP_100993109.1|8212446_8213310_-|arsenite-methyltransferase
METAEQIKEVVRQKYGAIAEQPEENSCCGPTSCCGPETVANVPIDMTVGYDELKGYVAEADLGLGCGLPTQFAQIKPGDTVVDLGSGAGNDCFVARAETGETGRVIGLDMTPAMIDRARKNTKTLGFTNVEFVYGDIEDMPLPSNLADVVVSNCVMNLVPDKQKAVAETFRILKPGGHFSISDIVLKGELPAGLQQDAELYVGCVSGAIQKADYLQLVQESGFTNITVRKEREISLPDDVLKNYLSVEEIADYRQQDKGIYSVTVFAQKPADAPTATASCCGPDCCN

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Crispr_ID: NZ_CP025096_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_10

8412620-8415253

Unclear

Consensus_repeat	Method
GTCTCAATCGCACCTTCGGGTATTGAAAT	PILER-CR
GTCTCAATCGCACCTTCGGGTATTGAAAT	CRISPRCasFinder
GTCTCAATCGCACCTTCGGGTATTGAAAT	CRT

40 spacers

cas2,cas4,cas3,cas7b,cas8b4,cas5,cas6,WYL,PD-DExK

The CRISPR arrays of NZ_CP025096_10

>merge|NZ_CP025096|10|8412620-8415253|PILER-CR,CRISPRCasFinder,CRT
GTCTCAATCGCACCTTCGGGTATTGAAATTTTGTGAGATACACTGCCCACGTTGCGTAACACATGTCTCAATCGCACCTTCGGGTATTGAAATCCGATGGCGTCTATCTGCTCCTGATAGTACATTACCGTCTCAATCGCACCTTCGGGTATTGAAATGCAAATAGGTGATATGGGCTATCCCATGGTGGATATGTCTCAATCGCACCTTCGGGTATTGAAATTTATCCTGCGCCACGCCTGGCACACTGGCCACCAGTGTCTCAATCGCACCTTCGGGTATTGAAATATTGTTTATGCCCATCAAAAGGAAGCGGAGTGGTCGGTCTCAATCGCACCTTCGGGTATTGAAATTTACTCTCCACACTCGTTACAGCCCAAATCGTTGCCGTCTCAATCGCACCTTCGGGTATTGAAATCCGGTCGTGTCCATTATGTTTTGCTGAGTTTATCGAACGTCTCAATCGCACCTTCGGGTATTGAAATTTAATGGTGATCAGGGCTTGCTTGCGATCCTGACCAGGTCTCAATCGCACCTTCGGGTATTGAAATTTGGCGACGTAATAGTCACCATCCGGCAGATACACGGGTCTCAATCGCACCTTCGGGTATTGAAATGTTCTGACATTCCATACACTACGGCTAACGGCACGGTCTCAATCGCACCTTCGGGTATTGAAATTTCCCATCGGTCCACCCAGCAGCGTGCCGCCAATCGGTCTCAATCGCACCTTCGGGTATTGAAATATGGGCTGGATTTGCATCTCCTGCGACGTGTACGACTGTCTCAATCGCACCTTCGGGTATTGAAATTTCTTATTGACAAAAAAAGATGAAATGTACCCACTACGTCTCAATCGCACCTTCGGGTATTGAAATTTCCGGATTCTGGAGGGGTCGACTGTGGCCGCTGTGTCTCAATCGCACCTTCGGGTATTGAAATCAAGTGTTCAGCTTTGTATTGATCGTACCAATACACGTCTCAATCGCACCTTCGGGTATTGAAATTTGCATCACACGCTCATTGGTCGAGTTATAGCGGTCAGGTCTCAATCGCACCTTCGGGTATTGAAATTTATACCTGCCAGCGTCCAGGCGTGATCGAAGCGCGAGTCTCAATCGCACCTTCGGGTATTGAAATTTGACACCATCAAGGATAAAACGCAGCTCACGGCCAAGTCTCAATCGCACCTTCGGGTATTGAAATTCTTATGTCTGCGCGAACTTCATCGGGCAAATAGACAGTCTCAATCGCACCTTCGGGTATTGAAATGTGATCTTGTCCTGCAGGCGGTTGGCCTGTACACTGAAGTCTCAATCGCACCTTCGGGTATTGAAATCATGAGCTTCAAGGATGATGCTGATTTCGAGGGCTGTCTCAATCGCACCTTCGGGTATTGAAATGAACTGGTGGTGTAGTCGGTAATGGTCGGCGGTGTGTCTCAATCGCACCTTCGGGTATTGAAATTTCGTAGATGGCCACCGGGTAGTCGGTAGGGAAGGGCGTCTCAATCGCACCTTCGGGTATTGAAATAAAGTGTCTTCGGATGGGGTATGATGCTGACCATATGTCTCAATCGCACCTTCGGGTATTGAAATAAAGTGTCTTCGGATGGGGTATGATGCTGACCATATGTCTCAATCGCACCTTCGGGTATTGAAATAAGTCTCCCCATTGCCTATACCCTCGACGCTGATTGGTCTCAATCGCACCTTCGGGTATTGAAATCAGGCTATATCCCCTTTGATGAACGCACTCGTTACGTCTCAATCGCACCTTCGGGTATTGAAATATGATTGATACAACGCTTGAGAGAACCGGCAAATACTGTCTCAATCGCACCTTCGGGTATTGAAATTTGGGCGTTTTTCTGATACGAAAACAATTATGCTTGCGTCTCAATCGCACCTTCGGGTATTGAAATTAATATGGACATTACCGGCAAGCACATTGACTCGGGTCTCAATCGCACCTTCGGGTATTGAAATGCTTTGGGATATGGTCTGGCGGGACGTGTACAAAACGTCTCAATCGCACCTTCGGGTATTGAAATTAACGGCAGATCAATACAAAACCTCTACTCCTCCGCGTCTCAATCGCACCTTCGGGTATTGAAATGAGAATGGCGGTATGGCCTTGATTGCTCCTACAGCCGTCTCAATCGCACCTTCGGGTATTGAAATCAAGGTTGAGCAGATTGACGCGGCTACGCTTCTCAGTCTCAATCGCACCTTCGGGTATTGAAATTTTCTGACGGGCGCTACACTGGAACTGCTGCAACAGTCTCAATCGCACCTTCGGGTATTGAAATTTCTTCATTCGCCTTTCTAATAGTCCGTCTCCTTTGGTCTCAATCGCACCTTCGGGTATTGAAATCTATTCAAAACTCAAGCAATCGGGCTATTGATGATAGTCTCAATCGCACCTTCGGGTATTGAAATAAACAGAATAATATATGGCTTTTGTCTTGATCTCAGAGTCTCAATCGCACCTTCGGGTATTGAAATGCGATCGAGTTACTAAACTCAGTTTTCAATCGAGTCTCAATCGCACCTTCGGGTATTGAAATTATCGGGCATGATACGCCAATTAAGGGAATTCTCAAGTCTCAATCGCACCTTCGGGTATTGAAAT

>NZ_CP025096|10|3|8412620-8415253|PILER-CR
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTTGTGAGATACACTGCCCACGTTGCGTAACACAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	CCGATGGCGTCTATCTGCTCCTGATAGTACATTACC
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCAAATAGGTGATATGGGCTATCCCATGGTGGATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTATCCTGCGCCACGCCTGGCACACTGGCCACCAGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATTGTTTATGCCCATCAAAAGGAAGCGGAGTGGTCG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTACTCTCCACACTCGTTACAGCCCAAATCGTTGCC
GTCTCAATCGCACCTTCGGGTATTGAAAT	CCGGTCGTGTCCATTATGTTTTGCTGAGTTTATCGAAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTAATGGTGATCAGGGCTTGCTTGCGATCCTGACCAG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGGCGACGTAATAGTCACCATCCGGCAGATACACGG
GTCTCAATCGCACCTTCGGGTATTGAAAT	GTTCTGACATTCCATACACTACGGCTAACGGCACG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCCCATCGGTCCACCCAGCAGCGTGCCGCCAATCG
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATGGGCTGGATTTGCATCTCCTGCGACGTGTACGACT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCTTATTGACAAAAAAAGATGAAATGTACCCACTAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCCGGATTCTGGAGGGGTCGACTGTGGCCGCTGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAAGTGTTCAGCTTTGTATTGATCGTACCAATACAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGCATCACACGCTCATTGGTCGAGTTATAGCGGTCAG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTATACCTGCCAGCGTCCAGGCGTGATCGAAGCGCGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGACACCATCAAGGATAAAACGCAGCTCACGGCCAA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TCTTATGTCTGCGCGAACTTCATCGGGCAAATAGACA
GTCTCAATCGCACCTTCGGGTATTGAAAT	GTGATCTTGTCCTGCAGGCGGTTGGCCTGTACACTGAA
GTCTCAATCGCACCTTCGGGTATTGAAAT	CATGAGCTTCAAGGATGATGCTGATTTCGAGGGCT
GTCTCAATCGCACCTTCGGGTATTGAAAT	GAACTGGTGGTGTAGTCGGTAATGGTCGGCGGTGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCGTAGATGGCCACCGGGTAGTCGGTAGGGAAGGGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAAGTGTCTTCGGATGGGGTATGATGCTGACCATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAAGTGTCTTCGGATGGGGTATGATGCTGACCATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAGTCTCCCCATTGCCTATACCCTCGACGCTGATTG
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAGGCTATATCCCCTTTGATGAACGCACTCGTTAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATGATTGATACAACGCTTGAGAGAACCGGCAAATACT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGGGCGTTTTTCTGATACGAAAACAATTATGCTTGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TAATATGGACATTACCGGCAAGCACATTGACTCGG
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCTTTGGGATATGGTCTGGCGGGACGTGTACAAAAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TAACGGCAGATCAATACAAAACCTCTACTCCTCCGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	GAGAATGGCGGTATGGCCTTGATTGCTCCTACAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAAGGTTGAGCAGATTGACGCGGCTACGCTTCTCA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTTCTGACGGGCGCTACACTGGAACTGCTGCAACA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCTTCATTCGCCTTTCTAATAGTCCGTCTCCTTTG
GTCTCAATCGCACCTTCGGGTATTGAAAT	CTATTCAAAACTCAAGCAATCGGGCTATTGATGATA
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAACAGAATAATATATGGCTTTTGTCTTGATCTCAGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCGATCGAGTTACTAAACTCAGTTTTCAATCGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TATCGGGCATGATACGCCAATTAAGGGAATTCTCAA
GTCTCAATCGCACCTTCGGGTATTGAAAT

>NZ_CP025096|10|10|8412620-8415253|CRISPRCasFinder
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTTGTGAGATACACTGCCCACGTTGCGTAACACAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	CCGATGGCGTCTATCTGCTCCTGATAGTACATTACC
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCAAATAGGTGATATGGGCTATCCCATGGTGGATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTATCCTGCGCCACGCCTGGCACACTGGCCACCAGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATTGTTTATGCCCATCAAAAGGAAGCGGAGTGGTCG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTACTCTCCACACTCGTTACAGCCCAAATCGTTGCC
GTCTCAATCGCACCTTCGGGTATTGAAAT	CCGGTCGTGTCCATTATGTTTTGCTGAGTTTATCGAAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTAATGGTGATCAGGGCTTGCTTGCGATCCTGACCAG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGGCGACGTAATAGTCACCATCCGGCAGATACACGG
GTCTCAATCGCACCTTCGGGTATTGAAAT	GTTCTGACATTCCATACACTACGGCTAACGGCACG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCCCATCGGTCCACCCAGCAGCGTGCCGCCAATCG
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATGGGCTGGATTTGCATCTCCTGCGACGTGTACGACT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCTTATTGACAAAAAAAGATGAAATGTACCCACTAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCCGGATTCTGGAGGGGTCGACTGTGGCCGCTGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAAGTGTTCAGCTTTGTATTGATCGTACCAATACAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGCATCACACGCTCATTGGTCGAGTTATAGCGGTCAG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTATACCTGCCAGCGTCCAGGCGTGATCGAAGCGCGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGACACCATCAAGGATAAAACGCAGCTCACGGCCAA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TCTTATGTCTGCGCGAACTTCATCGGGCAAATAGACA
GTCTCAATCGCACCTTCGGGTATTGAAAT	GTGATCTTGTCCTGCAGGCGGTTGGCCTGTACACTGAA
GTCTCAATCGCACCTTCGGGTATTGAAAT	CATGAGCTTCAAGGATGATGCTGATTTCGAGGGCT
GTCTCAATCGCACCTTCGGGTATTGAAAT	GAACTGGTGGTGTAGTCGGTAATGGTCGGCGGTGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCGTAGATGGCCACCGGGTAGTCGGTAGGGAAGGGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAAGTGTCTTCGGATGGGGTATGATGCTGACCATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAAGTGTCTTCGGATGGGGTATGATGCTGACCATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAGTCTCCCCATTGCCTATACCCTCGACGCTGATTG
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAGGCTATATCCCCTTTGATGAACGCACTCGTTAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATGATTGATACAACGCTTGAGAGAACCGGCAAATACT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGGGCGTTTTTCTGATACGAAAACAATTATGCTTGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TAATATGGACATTACCGGCAAGCACATTGACTCGG
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCTTTGGGATATGGTCTGGCGGGACGTGTACAAAAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TAACGGCAGATCAATACAAAACCTCTACTCCTCCGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	GAGAATGGCGGTATGGCCTTGATTGCTCCTACAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAAGGTTGAGCAGATTGACGCGGCTACGCTTCTCA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTTCTGACGGGCGCTACACTGGAACTGCTGCAACA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCTTCATTCGCCTTTCTAATAGTCCGTCTCCTTTG
GTCTCAATCGCACCTTCGGGTATTGAAAT	CTATTCAAAACTCAAGCAATCGGGCTATTGATGATA
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAACAGAATAATATATGGCTTTTGTCTTGATCTCAGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCGATCGAGTTACTAAACTCAGTTTTCAATCGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TATCGGGCATGATACGCCAATTAAGGGAATTCTCAA
GTCTCAATCGCACCTTCGGGTATTGAAAT

>NZ_CP025096|10|3|8412620-8415253|CRT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTTGTGAGATACACTGCCCACGTTGCGTAACACAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	CCGATGGCGTCTATCTGCTCCTGATAGTACATTACC
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCAAATAGGTGATATGGGCTATCCCATGGTGGATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTATCCTGCGCCACGCCTGGCACACTGGCCACCAGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATTGTTTATGCCCATCAAAAGGAAGCGGAGTGGTCG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTACTCTCCACACTCGTTACAGCCCAAATCGTTGCC
GTCTCAATCGCACCTTCGGGTATTGAAAT	CCGGTCGTGTCCATTATGTTTTGCTGAGTTTATCGAAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTAATGGTGATCAGGGCTTGCTTGCGATCCTGACCAG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGGCGACGTAATAGTCACCATCCGGCAGATACACGG
GTCTCAATCGCACCTTCGGGTATTGAAAT	GTTCTGACATTCCATACACTACGGCTAACGGCACG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCCCATCGGTCCACCCAGCAGCGTGCCGCCAATCG
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATGGGCTGGATTTGCATCTCCTGCGACGTGTACGACT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCTTATTGACAAAAAAAGATGAAATGTACCCACTAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCCGGATTCTGGAGGGGTCGACTGTGGCCGCTGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAAGTGTTCAGCTTTGTATTGATCGTACCAATACAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGCATCACACGCTCATTGGTCGAGTTATAGCGGTCAG
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTATACCTGCCAGCGTCCAGGCGTGATCGAAGCGCGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGACACCATCAAGGATAAAACGCAGCTCACGGCCAA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TCTTATGTCTGCGCGAACTTCATCGGGCAAATAGACA
GTCTCAATCGCACCTTCGGGTATTGAAAT	GTGATCTTGTCCTGCAGGCGGTTGGCCTGTACACTGAA
GTCTCAATCGCACCTTCGGGTATTGAAAT	CATGAGCTTCAAGGATGATGCTGATTTCGAGGGCT
GTCTCAATCGCACCTTCGGGTATTGAAAT	GAACTGGTGGTGTAGTCGGTAATGGTCGGCGGTGT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCGTAGATGGCCACCGGGTAGTCGGTAGGGAAGGGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAAGTGTCTTCGGATGGGGTATGATGCTGACCATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAAGTGTCTTCGGATGGGGTATGATGCTGACCATAT
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAGTCTCCCCATTGCCTATACCCTCGACGCTGATTG
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAGGCTATATCCCCTTTGATGAACGCACTCGTTAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	ATGATTGATACAACGCTTGAGAGAACCGGCAAATACT
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTGGGCGTTTTTCTGATACGAAAACAATTATGCTTGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TAATATGGACATTACCGGCAAGCACATTGACTCGG
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCTTTGGGATATGGTCTGGCGGGACGTGTACAAAAC
GTCTCAATCGCACCTTCGGGTATTGAAAT	TAACGGCAGATCAATACAAAACCTCTACTCCTCCGC
GTCTCAATCGCACCTTCGGGTATTGAAAT	GAGAATGGCGGTATGGCCTTGATTGCTCCTACAGCC
GTCTCAATCGCACCTTCGGGTATTGAAAT	CAAGGTTGAGCAGATTGACGCGGCTACGCTTCTCA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTTCTGACGGGCGCTACACTGGAACTGCTGCAACA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TTCTTCATTCGCCTTTCTAATAGTCCGTCTCCTTTG
GTCTCAATCGCACCTTCGGGTATTGAAAT	CTATTCAAAACTCAAGCAATCGGGCTATTGATGATA
GTCTCAATCGCACCTTCGGGTATTGAAAT	AAACAGAATAATATATGGCTTTTGTCTTGATCTCAGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	GCGATCGAGTTACTAAACTCAGTTTTCAATCGA
GTCTCAATCGCACCTTCGGGTATTGAAAT	TATCGGGCATGATACGCCAATTAAGGGAATTCTCAA
GTCTCAATCGCACCTTCGGGTATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100993273.1\|8420458_8420884_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993267.1\|8412139_8412403_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP025096.1\|WP_100993265.1\|8407947_8410434_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NZ_CP025096.1\|WP_100993260.1\|8402489_8403404_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP025096.1\|WP_100993270.1\|8416519_8416702_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP025096.1\|WP_100993272.1\|8419371_8419692_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993271.1\|8418574_8418799_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993259.1\|8401279_8402275_+\|DUF1016-domain-containing-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl\|CDD\|377634
NZ_CP025096.1\|WP_100993262.1\|8404592_8405378_+\|hypothetical-protein	cas5	cd09716_cas5_CAS-I-B	gnl\|CDD\|132527
NZ_CP025096.1\|WP_100994179.1\|8417252_8417690_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816171.1\|8416913_8417069_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993266.1\|8410430_8410982_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP025096.1\|WP_100993261.1\|8403904_8404573_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NZ_CP025096.1\|WP_100993258.1\|8400485_8400893_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993263.1\|8405374_8407009_+\|hypothetical-protein	cas8b4	cd09715_cas8b4_CAS-I-B	gnl\|CDD\|187846
NZ_CP025096.1\|WP_100993269.1\|8415739_8415985_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993264.1\|8407044_8407941_+\|type-I-PGING-CRISPR-associated-protein-Cas7/Csp1	cas7b	cd09717_cas7b_CAS-I-B	gnl\|CDD\|132528
NZ_CP025096.1\|WP_100993274.1\|8421090_8421510_-\|response-regulator	unknown	unknown	gnl\|CDD\|333815
NZ_CP025096.1\|WP_100993268.1\|8415308_8415746_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993275.1\|8421684_8422098_+\|response-regulator	unknown	unknown	gnl\|CDD\|381108

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993267.1\|8412139_8412403_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.37172e-23
NZ_CP025096.1\|WP_100993265.1\|8407947_8410434_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.24407e-72
NZ_CP025096.1\|WP_100993260.1\|8402489_8403404_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	8.78728e-28
NZ_CP025096.1\|WP_100993270.1\|8416519_8416702_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	6.41035e-05
NZ_CP025096.1\|WP_100993275.1\|8421684_8422098_+\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.75454e-40
NZ_CP025096.1\|WP_100993259.1\|8401279_8402275_+\|DUF1016-domain-containing-protein	gnl\|CDD\|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	1.00881e-74
NZ_CP025096.1\|WP_100993262.1\|8404592_8405378_+\|hypothetical-protein	gnl\|CDD\|132527	TIGR03488, cas_Cas5p, CRISPR-associated protein Cas5, subtype PGING. CC Members of this protein family are cas, or CRISPR-associated, proteins. The two sequences in the alignment seed are found within cas gene clusters that are adjacent to CRISPR DNA repeats in two members of the order Bacteroidales, Porphyromonas gingivalis W83 and Bacteroides forsythus ATCC 43037. This cas protein family is unique to the Pgingi (Porphyromonas gingivalis) subtype, but shows some sequence similarity to genes of the Cas5 type (see TIGR02593).	1.0565e-29
NZ_CP025096.1\|WP_100993266.1\|8410430_8410982_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	4.24314e-51
NZ_CP025096.1\|WP_100993261.1\|8403904_8404573_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.85093e-14
NZ_CP025096.1\|WP_100993263.1\|8405374_8407009_+\|hypothetical-protein	gnl\|CDD\|187846	cd09715, Csp2_I-U, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Predicted Cas8 ortholog.	8.30268e-69
NZ_CP025096.1\|WP_100993264.1\|8407044_8407941_+\|type-I-PGING-CRISPR-associated-protein-Cas7/Csp1	gnl\|CDD\|132528	TIGR03489, cas_csp1, CRISPR-associated protein Cas7/Csp1, subtype PGING. Members of this protein family are Csp1, a CRISPR-associated (cas) gene marker for the Pging subtype of CRISPR/cas system, as found in Porphyromonas gingivalis W83 and Bacteroides forsythus ATCC 43037. This protein belongs to the family of DevR (TIGR01875), a regulator of development in Myxococcus xanthus located in a cas gene region. A different branch of the DevR family, Cst2 (TIGR02585), is a marker for the Tneap subtype of CRISPR/cas system.	1.41129e-111
NZ_CP025096.1\|WP_100993274.1\|8421090_8421510_-\|response-regulator	gnl\|CDD\|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	0.000151043

>NZ_CP025096.1|WP_100993267.1|8412139_8412403_+|CRISPR-associated-endonuclease-Cas2
MPFCIAVYDVNQKRTGKMLKLFRRYLTWVQNSVFEGDLTPAQLKQLQQEADMLLQDNDGIVFYQLRDERYVERIALGVDITNRSRFL
>NZ_CP025096.1|WP_100993266.1|8410430_8410982_+|CRISPR-associated-protein-Cas4
MNITSKLRIGGMLVGYYRLCPRKAWLSMRGIWMEQESDTVALGRLLDEYSYDRSDKHIEINAEAPDGTPLVGKIDRATLKNGVLHETKKSRSCEDAHLWQVRFYLWLLTRNGVTRSDGSPFRGQLDYPLLRRTEWVTLEPEHIDELVATVSAIRELATQDVPPTRLLKRTFCTKCAFDELCYG
>NZ_CP025096.1|WP_100993265.1|8407947_8410434_+|CRISPR-associated-helicase-Cas3'
MEPLAKPSGITLRDHRQHVYDEALALLDAHPFWEKKYKELTGDDLRYRLKRVAWWHDAGKAHPTWRDACRSDYNLYRSWRQKNGMIIEEPDPSQNAVDFKKYEAAMRKAKKNSSPNLQNAGLRHEFDSLAQALNQLRGDDTITLTEQVAIAAHHGKLNHRHINRWQQDGKSQKDDTKGPYWSLWAKLNNESDLIGRTGKSSRSRDDWQLRVLERYRIAAVRSLLQLADTRASRRESGGITPDLEPFHYHFPDNWTKRDVQEAVLTGADQPICILRAKTGSGKTDASLLWAKHQIVGNQKPVVDEEKPEWAQKADRLTIAMPTRFTSNALAISVDKNVSSTGLYHSSAWYTRYGNVSDKERDDAKELHKLARGLATPVTVCTIDHLLLCLTGTKEDQHTSFFFLANSAVVFDEADFYDPFVQANLIVLLDTLRLLKVPVLIMSATVPDSLRVRYNIPDAIVDVKAGAQTAKCPIVWRGAVEGPKDVEGILKGMVRRGTGIVYANTVDRAYAYYQWFAEQFKKGGPKPILYHSRYTEPDKKAIEDELIAMLGKDAWTEHKNAEGIAILTQIGEMSINISAPIMLSDACPWDRLAQRAGRLDRFGLDPMGGILYVVEPLRDGTSYPAPYGELPKGGKGWIPAEAFTQTVQELASEFDEIPTPVSSASFVERVNNLYREQPTFTSKIEQNRDRLKDLMKLNWMIVSNQHADEEQITVSGEWKSRDIPPQQTVFISLPEFDATEDEEGVYVFKNWDTYRGYELEAGISCPDYLVRMGNERKQLYPFVFRVGEDKDPHTVLILVDGIYTSETGLALLGKGEKTDRAKGVIESNS
>NZ_CP025096.1|WP_100993264.1|8407044_8407941_+|type-I-PGING-CRISPR-associated-protein-Cas7/Csp1
MKIKSITVTLLAPMSDHAANRGEKLLGNASSIKRRPDGRVYISGQMQRHALFSAIDRLNEDHPQRNGTYVANGDGPSTNVAKDLRSDLGGYLDTNKDDYSGRRTAPATATPGVAQATSQIGRDLLVRLRMDESKDSGRKQALATNEYSQNDLMQMSFHLDVGAVGVTKEYKYETEAHVATTYKNHLEGQDGEHARRVRLFLDATRSITDYANQARNATTAEPQKVLIVLDTKMSRKAVRYFAPGTNATEKTRILAELDNRDAIYFLGDDTNPDTLSVDEAYQQALAALDTNDLYTPVA
>NZ_CP025096.1|WP_100993263.1|8405374_8407009_+|hypothetical-protein
MIDLDFLHPYPRYGVAAALVEQNAFLDGLTTWQHVAELAWKAIDRALLRYTLFTSDDPLLETTEVLRFDYLDEKVLDPGKKSGQIAAKGYYLPPYVITTDGSSAATVAEARTIRDLLKKATEEDLIKTQKLKRSFAPLTSKVNNGRSSMAEPKSTLLEAAFTVVATLTEFKPAAQVSVGKGMANTTIIPDLPLVDGEFEPLIDFVQVFADLRVRKQNYQVKNDDMLLAKVDPKDRKYRRPQLFRGNYPNAPRDGSLGAISLVAAIGAWAREGGRFSHKQKDGTSREEPRAEFAERVLDQLAEKPLYILSYEGVGQEKYGHHLVDMALHYDLPAIVRAAHRAMPFGVEKLDDPKFKLYKRFFDRFLQQLDRPTFRDFMAARNEYPFELAPIFIKYMETEHHLSPELIASARAYGQSLNYAAYVTAESERQDDIKNKRRERPLSEYKNRILVQFESTILSAKTPTALLSQMGIIVGRLTGREMDSKAGFFMETAAGWPDSQLSLAQELITAFMRLSSYRPKEVTGDNAIPPEETIIDNPANDPMPA
>NZ_CP025096.1|WP_100993262.1|8404592_8405378_+|hypothetical-protein
MEQIDLSFFIEPPELTVTAMLQIDALAPLSMVAAQPGAYYRSQPAPTEFMLYGLLENALGWHLSATPRKQVMDDLKKSAKKSAKKNVAWAKSPWITGKPTGSPEIGFVSLLQYHVAFEGLEKPVQVDTFDDLWSQQLRDTGRSFFGGSRHYDASLSDLMTRERRGDVEFGDRAEHEVLRDESLLLAADGAKIQYKSVRSKFPHYYVSPTVREYVIPRSPYLFRLLTTPSVSALLKDAFNDPSAPLYIGSNDGWVDVSYEEL
>NZ_CP025096.1|WP_100993261.1|8403904_8404573_+|CRISPR-associated-endoribonuclease-Cas6
MRLQLNLTSNTQPVPFTYLYNLVGSLHKWIGENNLLHDGMSLYSFGRLTGAEKIGKHLYFPNGSTLSISFQNSDHAWAMAKGILKDDSLAFGMRVIEANEMPIPSFENRVRLATDGEIVVRTKRPDGSRQYLLWSDEAANEKMTQLMRKKLQAAGYNESHQTINIRFDRDYPKARTRLMDVKGIKHRGSICPVIIEGTPEAIEFAWLVGVGELTGSGFGALV
>NZ_CP025096.1|WP_100993260.1|8402489_8403404_+|WYL-domain-containing-protein
MNDSAKLRRQLHLIRCLDKPYTYPSLIQLHKYLLDHDIEQTSLATVERDINDIRTDYDISITYDRRQHGYFLDLPTDDEDISNFREFVRLLERRERLELLTQSGRSVAQYIQLEQHNGFRGLDLMAPLWNALQRRLVVTFNYQAYKDQPAEKRWVEPGLLFEYRNRWYLDGFDLDRNGERTFGLDRIVDLTMTPQSILPSRQTDYRAARRHVIGVTAPPGSPIERVCLRFRRPEAEYVLSLPLHNSQQTVAETPTHVDIELHVVLNHELEREIMAYGEEVEVLEPVTLRYIIINRIKSLSKIYI
>NZ_CP025096.1|WP_100993259.1|8401279_8402275_+|DUF1016-domain-containing-protein
MDQLVSDIRQIISQSRESAARSINHALALMYWHIGRVIVEDEQQGQQRATYGKALIKNLSAQLVAEFGENFSSRNLQLSRQFFLTYPIVNSLSSQLTWTHYKILVRLEETSKRAFYMAEAEKNAWTVRQLERQINSLLYERLLMSQDKESVLAIAQSQAKPTKPHQVIKDPIVLEFLGLKPQASYYEQDIEHAIITHIQEFLLELGNGFSFVAREKRIIIDSDEFKIDLVFYNRLLQCFVLLDLKMDKITHQDVGQLQMYVNYYDRDIKESYENPTIGVLLCADKNDAVVRYTLPENNTQLFASKYQLHLPTEQQLVEEIRKELTDDTKQL
>NZ_CP025096.1|WP_100993258.1|8400485_8400893_+|hypothetical-protein
MPFGAVEEQIIDAAKNYSTVLHKATELVSQATDDLFSGTPATIYLKKMGHRQLTSEELKNIITALGSAEDKQIVQDFQQAQLELSQRLQNTKNIGLLLKQAKIPYQQAYARFSRSDLWKPEQMIQIMEVLRRLQL
>NZ_CP025096.1|WP_100993268.1|8415308_8415746_+|hypothetical-protein
MLTINSQFMDRLVKLRMKQPKRIMREMVAAVLLDQLNIDQAAERYKVNRLTVLRWMRKVEEEAKASKQTTPIASDQPSPPTRKSTRRSAPEDEVKQLRTKLQSMEKELETANFKALYYSTLVRVAKHELGVDVEKKSVTKPSGLC
>NZ_CP025096.1|WP_100993269.1|8415739_8415985_+|hypothetical-protein
MLTNHPNISIRQLEGVLGFSRQGYYQYWQRQADQVNHDDDILKLVKKVRQDHPRIGGRKLYWLLQNAFLERAGPPFRFVAW
>NZ_CP025096.1|WP_100993270.1|8416519_8416702_-|transposase
MVKRRVFDEAFKEMAVELSYVKGSIQEAARELDIDPGRISKWRQRHKKKRSNVACQYHTY
>NZ_CP025096.1|WP_157816171.1|8416913_8417069_-|hypothetical-protein
MFPFLVMAYFSLLRMNDLPIGALQELDKRSSMLCWRSFLIHHELPRGLCSA
>NZ_CP025096.1|WP_100994179.1|8417252_8417690_+|hypothetical-protein
MFETIMNLVQQHAGQSVVNNPAIPNDQNDNVLQTVTGSIMNGLGQQAQGGGLGSLKGMATGQGDSSTLADHPATQGVQQTVQQDLMSKLGISPQVAMSVAGSLVPMVLSKLMHKADDPNDSSVDAGSLMSSLGGQGGGLGGLFGK
>NZ_CP025096.1|WP_100993271.1|8418574_8418799_+|hypothetical-protein
MVELIGTINRNPDNVDLIRNRNFGVVGVWEFREALYKAAKEVATYRQHQINHKPDEVLAQAVKTKGIDLENNRK
>NZ_CP025096.1|WP_100993272.1|8419371_8419692_-|hypothetical-protein
MKVNLLNTFILICLTACSSAPLDQRYSEAIGLGPLLEVMPPIGKTELGWIMLAKKANDENSVSNEGKTFRELSKQGLNMVKATKAQSFVDSINYKVEVDQRLKSNF
>NZ_CP025096.1|WP_100993273.1|8420458_8420884_+|hypothetical-protein
MKEKDKWYKGGRPEMKPEERAEKVVQVRFTQAEYNQLLARKATVKTQTVSSYVRAICLNKPLRLKPERSTYQDILLSLIQETRSDVLRIRVNINQAARRINSTTDYQDLQQEVTRMASDMVRFDAQLREVIAAVLKGGGEM
>NZ_CP025096.1|WP_100993274.1|8421090_8421510_-|response-regulator
MDTLKPWVALLDEDVDDYIFWQHGFRRWAQHLDLYWFSSVTEFLSATSLGHDKPVALVMDGVVPDGEEMKWLSTLLLHPSCQQACLIMLSAEVTQPQREAYLRLGASDHLQKPVRLQELQEIVSTVSTHIARKSELSGL
>NZ_CP025096.1|WP_100993275.1|8421684_8422098_+|response-regulator
MDQHTYPCVFIADDDEDDRYLLNLAFARHSPQCRLVFAHDGLDLLDALARYETSPELIILDMNMPRLNGFEALQALRQHSSYQRTPIVILTTSAAETDRQRAEQLGANEFITKPLKAELLGQIVTRLRVEWLEGNCC

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Crispr_ID: NZ_CP025096_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_11

8469694-8469787

Orphan

Consensus_repeat	Method
CTCGTTTTTGGGGGATCAAAACTCGTTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025096_11

>merge|NZ_CP025096|11|8469694-8469787|CRISPRCasFinder
CTCGTTTTTGGGGGATCAAAACTCGTTTTTCGAGGGATCAAAACTCGTTTTTGGGGGATCAAAACTCGTTTTTGGGGGATCAAAACTCGTTTTT

>NZ_CP025096|11|11|8469694-8469787|CRISPRCasFinder
CTCGTTTTTGGGGGATCAAAACTCGTTTTT	CGAGGGATCAAAACTCGTTTTTGGGGGATCAAAA
CTCGTTTTTGGGGGATCAAAACTCGTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100993336.1\|8480900_8481419_+\|damage-inducible-protein-DinB	unknown	unknown	gnl\|CDD\|368313
NZ_CP025096.1\|WP_100993330.1\|8474003_8474333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993323.1\|8466714_8467608_+\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NZ_CP025096.1\|WP_100993337.1\|8481497_8482112_+\|cytoplasmic-protein	unknown	unknown	gnl\|CDD\|128789
NZ_CP025096.1\|WP_100993325.1\|8468377_8468677_-\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|225481
NZ_CP025096.1\|WP_100993326.1\|8468669_8469626_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP025096.1\|WP_100993332.1\|8475410_8475617_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993317.1\|8463847_8464306_+\|response-regulator	unknown	unknown	gnl\|CDD\|381108
NZ_CP025096.1\|WP_100993319.1\|8465032_8465293_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993328.1\|8470899_8472015_+\|AhpC/TSA-family-protein	unknown	unknown	gnl\|CDD\|239264
NZ_CP025096.1\|WP_157816181.1\|8467591_8468233_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816180.1\|8464548_8464971_-\|BLUF-domain-containing-protein	unknown	unknown	gnl\|CDD\|377423
NZ_CP025096.1\|WP_100993334.1\|8476414_8477080_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|365969
NZ_CP025096.1\|WP_100993335.1\|8477298_8478336_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380801
NZ_CP025096.1\|WP_100993331.1\|8474329_8474572_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP025096.1\|WP_100993333.1\|8475671_8476160_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993321.1\|8465872_8466193_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993329.1\|8472302_8473031_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993320.1\|8465543_8465876_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993322.1\|8466361_8466718_+\|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl\|CDD\|368576

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993336.1\|8480900_8481419_+\|damage-inducible-protein-DinB	gnl\|CDD\|368313	pfam05163, DinB, DinB family. DNA damage-inducible (din) genes in Bacillus subtilis are coordinately regulated and together compose a global regulatory network that has been termed the SOS-like or SOB regulon. This family includes DinB from B. subtilis.	4.06345e-13
NZ_CP025096.1\|WP_100993323.1\|8466714_8467608_+\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	2.32151e-15
NZ_CP025096.1\|WP_100993337.1\|8481497_8482112_+\|cytoplasmic-protein	gnl\|CDD\|128789	smart00513, SAP, Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation.	0.00409611
NZ_CP025096.1\|WP_100993325.1\|8468377_8468677_-\|BrnT-family-toxin	gnl\|CDD\|225481	COG2929, COG2929, Uncharacterized protein conserved in bacteria [Function unknown].	6.79877e-12
NZ_CP025096.1\|WP_100993326.1\|8468669_8469626_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	7.04162e-47
NZ_CP025096.1\|WP_100993317.1\|8463847_8464306_+\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.06824e-21
NZ_CP025096.1\|WP_100993328.1\|8470899_8472015_+\|AhpC/TSA-family-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.33151e-37
NZ_CP025096.1\|WP_157816180.1\|8464548_8464971_-\|BLUF-domain-containing-protein	gnl\|CDD\|377423	pfam04940, BLUF, Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein. AppA is involved in the repression of photosynthesis genes in response to blue-light.	1.60626e-41
NZ_CP025096.1\|WP_100993334.1\|8476414_8477080_+\|recombinase-family-protein	gnl\|CDD\|365969	pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.	4.6508e-22
NZ_CP025096.1\|WP_100993335.1\|8477298_8478336_-\|hypothetical-protein	gnl\|CDD\|380801	cd20231, PFM_jacalin-like, pore-forming module of uncharacterized proteins which have an N-terminal jacalin-like lectin domain, and similar aerolysin-type beta-barrel pore-forming proteins. Jacalin-like lectins are sugar-binding protein domains. Proteins having these lectin domains may bind mono- or oligosaccharides with high specificity. Generally, pore-forming proteins (PFPs) are secreted as water-soluble monomers, which upon binding to target lipid membranes, oligomerize and form transmembrane pores detrimental to cells. Beta-PFPs form pores by transmembrane beta-barrels. Aerolysin-type beta-PFPs are believed to use an amphipathic beta-hairpin to form the beta-barrel. Many of this family are bacterial toxins. A significant portion of the monomeric subunit structure is re-organized to form the pore. Oligomers formed by members of the aerolysin family include: hepta- (aerolysin), octa- (Dln1), and nonameric oligomers (lysenin and monalysin).	4.8375e-33
NZ_CP025096.1\|WP_100993331.1\|8474329_8474572_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	5.43858e-08
NZ_CP025096.1\|WP_100993322.1\|8466361_8466718_+\|plasmid-mobilization-relaxosome-protein-MobC	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	1.92401e-05

>NZ_CP025096.1|WP_100993326.1|8468669_8469626_-|replication-initiation-protein
MNQAVEIRQHNAITTARYEYSELQLDIFLYLLSMLKRDKKDEIYEIVVKDLSTMTGKEYKYGYLRKATEEMGSRMFEISTSKSYEQIWMFQRVKYVIGEGRIEVRFSDDIKPYLFDLKDNFTSFELYAALRLGSKYAKRIYAICSQWKDKRQTQTFSLNEFKKMLFLLDDKGNEQFERLSDFKRYVLDASVKQINQRTDLEISYTLGKRGRSFDSVTFDVKAQPLAVVLPTKEEAAKTQTTLGGVSDAQYQNVRLLLENWNIKRADVISQIMNSAELIKEVNKFAYELQTGKVKVEKNVAGYLLTRLGLKQPKGVKNG
>NZ_CP025096.1|WP_100993325.1|8468377_8468677_-|BrnT-family-toxin
MAEFQWDSANIKHVIQDYPERANTTEEVESLFDDPKFNPLPDRVDSRGEQQYSGVGRSNQNRLLFVAFSVRNGQIRPISCRPAGRKARDSYAQDQEKTD
>NZ_CP025096.1|WP_157816181.1|8467591_8468233_+|hypothetical-protein
MAAVCKMDESQLITELLKGLTKDIEELKTRVGKLPTQTSADYGASLDGLTKAVQALQQQVKQAPAAVDLSAITSRLDRIEQLSRQHPDRKASQYVQVGALASGLMAVLLGIVTWLALSWRSERSAFEVSDWKWRNLRQVDPVYVRKIDSTYAVASQVKDGKDLADFHQWIIQQEQADATREAAHQAAEQAKAMNTQADELEQKASTKRRKKAN
>NZ_CP025096.1|WP_100993323.1|8466714_8467608_+|relaxase/mobilization-nuclease-domain-containing-protein
MIGKTSIGRSFKGCCGYNMEKVEKGKGEVILSQGVRDYEQKAMVADFVRQARLNPDLSRSVWHTAISFDPQDEARLRANPQLMQSVASDYLKGMGLDQSQYAVIEHRDTGHSHFHIIANRVANDGQTVSDSHNFSRSETLLRQIEQKYGLTPMNEQAQRKSLENLPERDRSRIEIRDQVRESLSHSTSDQELREELARHNISMIVNRDKAGQPRGISFEQVKVDQNGEEIRVAFKGSKLHQNLGMGQIQEQLGLNAQLRQKQALEIEQAKERAKAQEAEKSPQIDDKSPKRGYGRSM
>NZ_CP025096.1|WP_100993322.1|8466361_8466718_+|plasmid-mobilization-relaxosome-protein-MobC
MVENEPVKKKGGRPPSVKKRDKKINLYVTGLEELAIKKRAERAGLNLSDYCRQIVLTGQAQVRLTPEENATLNEVAKVGNNLNQIAHKANADGIRSIAFEASRLLQQLSQLLNKPSDL
>NZ_CP025096.1|WP_100993321.1|8465872_8466193_-|hypothetical-protein
MRTIIEAIDHPDWVLKDWKIKFLLSERMLHEVKKLARVGHWYDDPLVTDIWRDRLTICYDSIYGFYETFGIPPQIGDRLFDEDSGVIIQNRSIDGRLKTITFTISI
>NZ_CP025096.1|WP_100993320.1|8465543_8465876_+|hypothetical-protein
MEAENPVPTSDTKIDSPSKTNGPVTWSIRGVERDTRSVIEKAAERAGKTMGQYVNEDIRSLVQGQLSQSQLPAAPVDLQNQMDHLTKMVEALTNRMPEQGKKSFWQRLFS
>NZ_CP025096.1|WP_100993319.1|8465032_8465293_-|hypothetical-protein
MVILLLTAIDSAGEFREFACQLPDIDSGFALLTTIASLGHTLVKVRLLEESSWSYLPHEAFDEMPVLPIIKELEKDWQQLLTESPQ
>NZ_CP025096.1|WP_157816180.1|8464548_8464971_-|BLUF-domain-containing-protein
MTHCIIYFSTSSWSFTSEDIQDILQQSRSRNAQVGITGVLLYMHGHIIQVLEGDKPAVDDLFERIKKDTRHKQVICVLNQSIKAHLFSQWSMGYETLTTQQFDEIRTIIDLDKPKPVSETENESAIVKTLRGFYKINHQL
>NZ_CP025096.1|WP_100993317.1|8463847_8464306_+|response-regulator
MLPDYLSSRRNKSVPVLVIEDNTDHQLLIGYSLKAKVPRANPIFAQTAQEALRHLQSTCTDLGTFPQLVLLDLFLPDLAKGWALLTDLKKGYPLLPIVVFSSSKDIGIVRQAYELGAHSFLSKPSSLDDWESTFQTLNEYWFNIASLPSRSY
>NZ_CP025096.1|WP_100993328.1|8470899_8472015_+|AhpC/TSA-family-protein
MKSFLLIFLLLIPTLLWGQSNVYKIEGNIAKVKPGTIAYVRYAVEVEKKVYSDSAQIHNGKFSITGTVDQPHLARLFIDQNSIRFYLEPGAISIISLDSVQDAVVSRSPMNIDNQKLKKILKPTDEQMTMLQREYKAATPEQKKEKGFDERFEKRSDAISAQQGKLKAQFIQANPTSMLSLYVLKDYTDWFTPEFSEVELMFSQFSEAIKTSKPGKAYAQTLAVLQTTSVGATAPEFAQPDTSGKTISLSSFRGKYVLVDFWASWCVPCRAENPNLVKNFQQYKDKNFTVLGVSLDRPNAKEAWLKAIRKDGLDWTHVSDLKHWDSEVVKQYAIRLIPQNFLIGPDGKILAKNIRGEALGVKLAELFRNKP
>NZ_CP025096.1|WP_100993329.1|8472302_8473031_-|hypothetical-protein
MERWLSRVVLSSLAIALLSPSYGQLGTGGVVSQDQKGNVFTTFLVSTTYTGKAISTIRYLGSPFLGTNVWHQGSLQFRNGHQLAGKLSYNLITGTIFFQTSDSLETYPVVPDEFILEGRKFIGISHNDLGIWQMAYYQVVYDGQTKLLRRYQERLQPISRSVYPMRMPSDEKFDGRYIISEEFYVKRVSNSPKLIQLTQESLRKALPDAPSDLLTSETTTDLTQAKLIALITAYDSRKLANY
>NZ_CP025096.1|WP_100993330.1|8474003_8474333_+|hypothetical-protein
MEAENPAPTSDTKIDSPSKTNGPVTWSIRGVERDTRSVIEKAAERAGKTMGQYVNEDIRSLVQGQLSQSQLPAAPVDLQNQMDHLTKMVEALTNRMPEQGKKSFWQLAS
>NZ_CP025096.1|WP_100993331.1|8474329_8474572_-|transposase
MVKRRVFDEAFKEMAVELSYVKGSIQEAARELDIDPGRISKWRQRHKKNDQTLPANTTLTDEQQQIRRLQRELRESFEKL
>NZ_CP025096.1|WP_100993332.1|8475410_8475617_-|hypothetical-protein
MKKNHEFKLNDLVTLINPKAAQALEAANGAIDWPVPVISQYGQRVHCWNSQRREFTITLSATEIKKVD
>NZ_CP025096.1|WP_100993333.1|8475671_8476160_+|hypothetical-protein
MKAINIHFFSPTENQQPTAKAEKAAKPAKLLLTGYISSVGKLVLPAKTVAHLGVDLSKTGFKVGMDEGKRKAKSLYLVPSSSDAETFTFEKAAKSYTLALPFILTKSGVDFAKTKYDFTIRLFEFEGTTAFALQLAPEAAAVKVPYTGKPRGRKPRQASDAE
>NZ_CP025096.1|WP_100993334.1|8476414_8477080_+|recombinase-family-protein
MVKYVAYYRVSTQKQGRSGLGLDAQKAGIHAFCGEQLIGDFIEIESGGKTSRKELAKAIELCQKENAKLIAYRLDRVLRNLEILVALRLNKVMFTALDCLNDSDMIINIKAALAEDELRKISERTRAALHQKKARGFTLGKPDNFCAEGRQKGTGVGKHAARNHPANQQAAELIRLYQRDKMTLRAIAQQLNNTGFRTRTGKLFQAESVRRLMSKALVRQQ
>NZ_CP025096.1|WP_100993335.1|8477298_8478336_-|hypothetical-protein
METISQPIPAELFTRANPGETNDWPDYPSGPYYTPEYVVGGFGGSKFLSSEALNGLLVKRVEVWYDSKALKGVRLTYTDDSSTQAGQQKNEYAKLDINPGEIITSLKLWGNGVGTRTGRVEMTTNTGKTLAAGKDVSGQNTYVAPTGSGILVGYTGRGGQEIDMLGFIFFDNVSSVQLGDVHYSGAPEKGSAAGINVVALQQASFGPFNTETNWRFANAVTRTSSQSWTKSSTVKYYALVTVKADIFGIGGEATAGWERTTGSESSTEVTTEISLSWDTGGVLPAEYLVNALATVSQGQLDLPYSGQLTISFNSGNQVSVPVKGLYTNVVYGRSQAKGTLIPPSN
>NZ_CP025096.1|WP_100993336.1|8480900_8481419_+|damage-inducible-protein-DinB
MENTVQLSQTMVPIVLSPQQLLAHWQGHRGLTRRLIEAYPEEHFFSYSLGGMRPCSALIDEVLQMADQSMQGVVSGIWPSFGQGSEAPPKATTKEQVLAQWDRVTETINAHWPQIPSTRFQEVDKAFGLYEGPIYWFLFYLIDNEIHHRGQAYVYLRTLGVEPPAFWDRPQV
>NZ_CP025096.1|WP_100993337.1|8481497_8482112_+|cytoplasmic-protein
MNADKRPLLTRAIPVTDFSDYYWLKKELVDFCTRQGLKTSGSKLEITERIAHFLQTGRPPTDLARPSKSSNSADGPPLVVMMDAPITKNYTSGEHIRGFFKSVIGPHFHFTVGLMKFCKENPTKTFGDAVQYWQEEYHRKSDKSYQPEIGPQFEYNQYIRDFMAANAGASLKEAIRHWKQKRSARGDNKYSRDDLAYESSETNE

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP025096_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_12

8474623-8475115

Orphan

I-A,II-B,III-A

Consensus_repeat	Method
CTTCTAATCGTACCAGAGTGGAATTGAAAT	CRT
ATTTCAATTCCACTCTGGTACGATTAGAAG	PILER-CR
CTTCTAATCGTACCAGAGTGGAATTGAAAT	CRISPRCasFinder

7 spacers

The CRISPR arrays of NZ_CP025096_12

>merge|NZ_CP025096|12|8474623-8475115|CRT,PILER-CR,CRISPRCasFinder
AATGTAGCAAGTTCAGAGTGGAATTGAAATTCACTAACCCACACCCGGTACTGATCGAATTTAAGTCCTTCTAATCGTACCAGAGTGGAATTGAAATACCAAACTCGTCATTGATGTCTCCCAGGTCAATGAGCTTCTAATCGTACCAGAGTGGAATTGAAAGGTAGTAAACTTGGGGTCATTGCGGCCAATAGTGTTGACTTCTAATCGTACCAGAGTGGAATTGAAATATTAAAAGTTCCCATGACCATGCGTGATATGCTGCTCTTCTAATCGTACCAGAGTGGAATTGAAATCTGCTTAACGAAATGGTATAGGTGGGCTTACCGTGTCTTCTAATCGTACCAGAGTGGAATTGAAATTCCGGATATCGCGCTCGGTGTAGGACTGTACCGTGCTTCTAATCGTACCAGAGTGGAATTGAAATTAATAATGCCGGATAGGATACCCGCGCCGGTATTAACTTCTAATCGTACCAGAGTGGCATTAAAAC

>NZ_CP025096|12|4|8474623-8475115|CRT
AATGTAGCAAGTTCAGAGTGGAATTGAAAT	TCACTAACCCACACCCGGTACTGATCGAATTTAAGTC
CTTCTAATCGTACCAGAGTGGAATTGAAAT	ACCAAACTCGTCATTGATGTCTCCCAGGTCAATGAG
CTTCTAATCGTACCAGAGTGGAATTGAAAG	GTAGTAAACTTGGGGTCATTGCGGCCAATAGTGTTGA
CTTCTAATCGTACCAGAGTGGAATTGAAAT	ATTAAAAGTTCCCATGACCATGCGTGATATGCTGCT
CTTCTAATCGTACCAGAGTGGAATTGAAAT	CTGCTTAACGAAATGGTATAGGTGGGCTTACCGTGT
CTTCTAATCGTACCAGAGTGGAATTGAAAT	TCCGGATATCGCGCTCGGTGTAGGACTGTACCGTG
CTTCTAATCGTACCAGAGTGGAATTGAAAT	TAATAATGCCGGATAGGATACCCGCGCCGGTATTAA
CTTCTAATCGTACCAGAGTGGCATTAAAAC

>NZ_CP025096|12|4|8474690-8475049|PILER-CR
CTTCTAATCGTACCAGAGTGGAATTGAAAT	ACCAAACTCGTCATTGATGTCTCCCAGGTCAATGAG
CTTCTAATCGTACCAGAGTGGAATTGAAAG	GTAGTAAACTTGGGGTCATTGCGGCCAATAGTGTTGA
CTTCTAATCGTACCAGAGTGGAATTGAAAT	ATTAAAAGTTCCCATGACCATGCGTGATATGCTGCT
CTTCTAATCGTACCAGAGTGGAATTGAAAT	CTGCTTAACGAAATGGTATAGGTGGGCTTACCGTGT
CTTCTAATCGTACCAGAGTGGAATTGAAAT	TCCGGATATCGCGCTCGGTGTAGGACTGTACCGTG
CTTCTAATCGTACCAGAGTGGAATTGAAAT

>NZ_CP025096|12|12|8474690-8475115|CRISPRCasFinder
CTTCTAATCGTACCAGAGTGGAATTGAAAT	ACCAAACTCGTCATTGATGTCTCCCAGGTCAATGAG
CTTCTAATCGTACCAGAGTGGAATTGAAAG	GTAGTAAACTTGGGGTCATTGCGGCCAATAGTGTTGA
CTTCTAATCGTACCAGAGTGGAATTGAAAT	ATTAAAAGTTCCCATGACCATGCGTGATATGCTGCT
CTTCTAATCGTACCAGAGTGGAATTGAAAT	CTGCTTAACGAAATGGTATAGGTGGGCTTACCGTGT
CTTCTAATCGTACCAGAGTGGAATTGAAAT	TCCGGATATCGCGCTCGGTGTAGGACTGTACCGTG
CTTCTAATCGTACCAGAGTGGAATTGAAAT	TAATAATGCCGGATAGGATACCCGCGCCGGTATTAA
CTTCTAATCGTACCAGAGTGGCATTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100993336.1\|8480900_8481419_+\|damage-inducible-protein-DinB	unknown	unknown	gnl\|CDD\|368313
NZ_CP025096.1\|WP_100993341.1\|8486165_8487455_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP025096.1\|WP_100993330.1\|8474003_8474333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993323.1\|8466714_8467608_+\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NZ_CP025096.1\|WP_100993337.1\|8481497_8482112_+\|cytoplasmic-protein	unknown	unknown	gnl\|CDD\|128789
NZ_CP025096.1\|WP_100993325.1\|8468377_8468677_-\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|225481
NZ_CP025096.1\|WP_100993326.1\|8468669_8469626_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP025096.1\|WP_100993332.1\|8475410_8475617_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993339.1\|8483674_8485099_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368908
NZ_CP025096.1\|WP_100993328.1\|8470899_8472015_+\|AhpC/TSA-family-protein	unknown	unknown	gnl\|CDD\|239264
NZ_CP025096.1\|WP_157816181.1\|8467591_8468233_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993334.1\|8476414_8477080_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|365969
NZ_CP025096.1\|WP_100993335.1\|8477298_8478336_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380801
NZ_CP025096.1\|WP_100993338.1\|8482172_8483552_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993333.1\|8475671_8476160_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993340.1\|8485378_8485780_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993321.1\|8465872_8466193_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993329.1\|8472302_8473031_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993331.1\|8474329_8474572_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP025096.1\|WP_100993322.1\|8466361_8466718_+\|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl\|CDD\|368576

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993336.1\|8480900_8481419_+\|damage-inducible-protein-DinB	gnl\|CDD\|368313	pfam05163, DinB, DinB family. DNA damage-inducible (din) genes in Bacillus subtilis are coordinately regulated and together compose a global regulatory network that has been termed the SOS-like or SOB regulon. This family includes DinB from B. subtilis.	4.06345e-13
NZ_CP025096.1\|WP_100993323.1\|8466714_8467608_+\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	2.32151e-15
NZ_CP025096.1\|WP_100993337.1\|8481497_8482112_+\|cytoplasmic-protein	gnl\|CDD\|128789	smart00513, SAP, Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation.	0.00409611
NZ_CP025096.1\|WP_100993325.1\|8468377_8468677_-\|BrnT-family-toxin	gnl\|CDD\|225481	COG2929, COG2929, Uncharacterized protein conserved in bacteria [Function unknown].	6.79877e-12
NZ_CP025096.1\|WP_100993326.1\|8468669_8469626_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	7.04162e-47
NZ_CP025096.1\|WP_100993339.1\|8483674_8485099_+\|hypothetical-protein	gnl\|CDD\|368908	pfam06439, DUF1080, Domain of Unknown Function (DUF1080). This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. However, the structure surrounding the active site differs from that of the endo-1,3-1,4-beta glucanase.	8.39325e-06
NZ_CP025096.1\|WP_100993328.1\|8470899_8472015_+\|AhpC/TSA-family-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.33151e-37
NZ_CP025096.1\|WP_100993334.1\|8476414_8477080_+\|recombinase-family-protein	gnl\|CDD\|365969	pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.	4.6508e-22
NZ_CP025096.1\|WP_100993335.1\|8477298_8478336_-\|hypothetical-protein	gnl\|CDD\|380801	cd20231, PFM_jacalin-like, pore-forming module of uncharacterized proteins which have an N-terminal jacalin-like lectin domain, and similar aerolysin-type beta-barrel pore-forming proteins. Jacalin-like lectins are sugar-binding protein domains. Proteins having these lectin domains may bind mono- or oligosaccharides with high specificity. Generally, pore-forming proteins (PFPs) are secreted as water-soluble monomers, which upon binding to target lipid membranes, oligomerize and form transmembrane pores detrimental to cells. Beta-PFPs form pores by transmembrane beta-barrels. Aerolysin-type beta-PFPs are believed to use an amphipathic beta-hairpin to form the beta-barrel. Many of this family are bacterial toxins. A significant portion of the monomeric subunit structure is re-organized to form the pore. Oligomers formed by members of the aerolysin family include: hepta- (aerolysin), octa- (Dln1), and nonameric oligomers (lysenin and monalysin).	4.8375e-33
NZ_CP025096.1\|WP_100993341.1\|8486165_8487455_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.51538e-48
NZ_CP025096.1\|WP_100993331.1\|8474329_8474572_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	5.43858e-08
NZ_CP025096.1\|WP_100993322.1\|8466361_8466718_+\|plasmid-mobilization-relaxosome-protein-MobC	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	1.92401e-05

>NZ_CP025096.1|WP_100993331.1|8474329_8474572_-|transposase
MVKRRVFDEAFKEMAVELSYVKGSIQEAARELDIDPGRISKWRQRHKKNDQTLPANTTLTDEQQQIRRLQRELRESFEKL
>NZ_CP025096.1|WP_100993330.1|8474003_8474333_+|hypothetical-protein
MEAENPAPTSDTKIDSPSKTNGPVTWSIRGVERDTRSVIEKAAERAGKTMGQYVNEDIRSLVQGQLSQSQLPAAPVDLQNQMDHLTKMVEALTNRMPEQGKKSFWQLAS
>NZ_CP025096.1|WP_100993329.1|8472302_8473031_-|hypothetical-protein
MERWLSRVVLSSLAIALLSPSYGQLGTGGVVSQDQKGNVFTTFLVSTTYTGKAISTIRYLGSPFLGTNVWHQGSLQFRNGHQLAGKLSYNLITGTIFFQTSDSLETYPVVPDEFILEGRKFIGISHNDLGIWQMAYYQVVYDGQTKLLRRYQERLQPISRSVYPMRMPSDEKFDGRYIISEEFYVKRVSNSPKLIQLTQESLRKALPDAPSDLLTSETTTDLTQAKLIALITAYDSRKLANY
>NZ_CP025096.1|WP_100993328.1|8470899_8472015_+|AhpC/TSA-family-protein
MKSFLLIFLLLIPTLLWGQSNVYKIEGNIAKVKPGTIAYVRYAVEVEKKVYSDSAQIHNGKFSITGTVDQPHLARLFIDQNSIRFYLEPGAISIISLDSVQDAVVSRSPMNIDNQKLKKILKPTDEQMTMLQREYKAATPEQKKEKGFDERFEKRSDAISAQQGKLKAQFIQANPTSMLSLYVLKDYTDWFTPEFSEVELMFSQFSEAIKTSKPGKAYAQTLAVLQTTSVGATAPEFAQPDTSGKTISLSSFRGKYVLVDFWASWCVPCRAENPNLVKNFQQYKDKNFTVLGVSLDRPNAKEAWLKAIRKDGLDWTHVSDLKHWDSEVVKQYAIRLIPQNFLIGPDGKILAKNIRGEALGVKLAELFRNKP
>NZ_CP025096.1|WP_100993326.1|8468669_8469626_-|replication-initiation-protein
MNQAVEIRQHNAITTARYEYSELQLDIFLYLLSMLKRDKKDEIYEIVVKDLSTMTGKEYKYGYLRKATEEMGSRMFEISTSKSYEQIWMFQRVKYVIGEGRIEVRFSDDIKPYLFDLKDNFTSFELYAALRLGSKYAKRIYAICSQWKDKRQTQTFSLNEFKKMLFLLDDKGNEQFERLSDFKRYVLDASVKQINQRTDLEISYTLGKRGRSFDSVTFDVKAQPLAVVLPTKEEAAKTQTTLGGVSDAQYQNVRLLLENWNIKRADVISQIMNSAELIKEVNKFAYELQTGKVKVEKNVAGYLLTRLGLKQPKGVKNG
>NZ_CP025096.1|WP_100993325.1|8468377_8468677_-|BrnT-family-toxin
MAEFQWDSANIKHVIQDYPERANTTEEVESLFDDPKFNPLPDRVDSRGEQQYSGVGRSNQNRLLFVAFSVRNGQIRPISCRPAGRKARDSYAQDQEKTD
>NZ_CP025096.1|WP_157816181.1|8467591_8468233_+|hypothetical-protein
MAAVCKMDESQLITELLKGLTKDIEELKTRVGKLPTQTSADYGASLDGLTKAVQALQQQVKQAPAAVDLSAITSRLDRIEQLSRQHPDRKASQYVQVGALASGLMAVLLGIVTWLALSWRSERSAFEVSDWKWRNLRQVDPVYVRKIDSTYAVASQVKDGKDLADFHQWIIQQEQADATREAAHQAAEQAKAMNTQADELEQKASTKRRKKAN
>NZ_CP025096.1|WP_100993323.1|8466714_8467608_+|relaxase/mobilization-nuclease-domain-containing-protein
MIGKTSIGRSFKGCCGYNMEKVEKGKGEVILSQGVRDYEQKAMVADFVRQARLNPDLSRSVWHTAISFDPQDEARLRANPQLMQSVASDYLKGMGLDQSQYAVIEHRDTGHSHFHIIANRVANDGQTVSDSHNFSRSETLLRQIEQKYGLTPMNEQAQRKSLENLPERDRSRIEIRDQVRESLSHSTSDQELREELARHNISMIVNRDKAGQPRGISFEQVKVDQNGEEIRVAFKGSKLHQNLGMGQIQEQLGLNAQLRQKQALEIEQAKERAKAQEAEKSPQIDDKSPKRGYGRSM
>NZ_CP025096.1|WP_100993322.1|8466361_8466718_+|plasmid-mobilization-relaxosome-protein-MobC
MVENEPVKKKGGRPPSVKKRDKKINLYVTGLEELAIKKRAERAGLNLSDYCRQIVLTGQAQVRLTPEENATLNEVAKVGNNLNQIAHKANADGIRSIAFEASRLLQQLSQLLNKPSDL
>NZ_CP025096.1|WP_100993321.1|8465872_8466193_-|hypothetical-protein
MRTIIEAIDHPDWVLKDWKIKFLLSERMLHEVKKLARVGHWYDDPLVTDIWRDRLTICYDSIYGFYETFGIPPQIGDRLFDEDSGVIIQNRSIDGRLKTITFTISI
>NZ_CP025096.1|WP_100993332.1|8475410_8475617_-|hypothetical-protein
MKKNHEFKLNDLVTLINPKAAQALEAANGAIDWPVPVISQYGQRVHCWNSQRREFTITLSATEIKKVD
>NZ_CP025096.1|WP_100993333.1|8475671_8476160_+|hypothetical-protein
MKAINIHFFSPTENQQPTAKAEKAAKPAKLLLTGYISSVGKLVLPAKTVAHLGVDLSKTGFKVGMDEGKRKAKSLYLVPSSSDAETFTFEKAAKSYTLALPFILTKSGVDFAKTKYDFTIRLFEFEGTTAFALQLAPEAAAVKVPYTGKPRGRKPRQASDAE
>NZ_CP025096.1|WP_100993334.1|8476414_8477080_+|recombinase-family-protein
MVKYVAYYRVSTQKQGRSGLGLDAQKAGIHAFCGEQLIGDFIEIESGGKTSRKELAKAIELCQKENAKLIAYRLDRVLRNLEILVALRLNKVMFTALDCLNDSDMIINIKAALAEDELRKISERTRAALHQKKARGFTLGKPDNFCAEGRQKGTGVGKHAARNHPANQQAAELIRLYQRDKMTLRAIAQQLNNTGFRTRTGKLFQAESVRRLMSKALVRQQ
>NZ_CP025096.1|WP_100993335.1|8477298_8478336_-|hypothetical-protein
METISQPIPAELFTRANPGETNDWPDYPSGPYYTPEYVVGGFGGSKFLSSEALNGLLVKRVEVWYDSKALKGVRLTYTDDSSTQAGQQKNEYAKLDINPGEIITSLKLWGNGVGTRTGRVEMTTNTGKTLAAGKDVSGQNTYVAPTGSGILVGYTGRGGQEIDMLGFIFFDNVSSVQLGDVHYSGAPEKGSAAGINVVALQQASFGPFNTETNWRFANAVTRTSSQSWTKSSTVKYYALVTVKADIFGIGGEATAGWERTTGSESSTEVTTEISLSWDTGGVLPAEYLVNALATVSQGQLDLPYSGQLTISFNSGNQVSVPVKGLYTNVVYGRSQAKGTLIPPSN
>NZ_CP025096.1|WP_100993336.1|8480900_8481419_+|damage-inducible-protein-DinB
MENTVQLSQTMVPIVLSPQQLLAHWQGHRGLTRRLIEAYPEEHFFSYSLGGMRPCSALIDEVLQMADQSMQGVVSGIWPSFGQGSEAPPKATTKEQVLAQWDRVTETINAHWPQIPSTRFQEVDKAFGLYEGPIYWFLFYLIDNEIHHRGQAYVYLRTLGVEPPAFWDRPQV
>NZ_CP025096.1|WP_100993337.1|8481497_8482112_+|cytoplasmic-protein
MNADKRPLLTRAIPVTDFSDYYWLKKELVDFCTRQGLKTSGSKLEITERIAHFLQTGRPPTDLARPSKSSNSADGPPLVVMMDAPITKNYTSGEHIRGFFKSVIGPHFHFTVGLMKFCKENPTKTFGDAVQYWQEEYHRKSDKSYQPEIGPQFEYNQYIRDFMAANAGASLKEAIRHWKQKRSARGDNKYSRDDLAYESSETNE
>NZ_CP025096.1|WP_100993338.1|8482172_8483552_-|hypothetical-protein
MSSPPIPIAIAKLKVQLETQLGWGSSETWSNYDVERLSEHIGQQTGVSLSVSTLKRVLGKVDSKSTPSLTTLNTLAQFLGYTDWRDFQLKTAETAAIPVEQPVPVSLVKKPQWIIPWLVLALLGIFLLGLVSFLLRREPPYSPTDFRFSSSTIRTRGLPNSVVFSYDATKARDDDSVFISQSWDTRRKVLVHKNDHHYSAIYYYPGFYRAKLMVGGQVLREHDLQINTDGWLGLVEADWGQEPLYLNPSDIISAQTVHITGELLEKHGVKRNSSSPKIILVNQQTIKGIRTDAFEFETEVKSLNEAGTDACQRVEVVLHAKNDLLVVPLVEPGCVGDIYVAAYGYYASSRKADLSGFGCHPTQWNQLRVSCRSGLVTFFLNQRAVYQARIKNRPAEIIGVQVRFNGPGAVRNTWLQGATDKVIFEGKSDISPFINGISSNARFSKQTYTISVVSSRRVC
>NZ_CP025096.1|WP_100993339.1|8483674_8485099_+|hypothetical-protein
MKKVFLMMFVLLATQGLAQKNNLSLASKRLDYAVPLTASQWSFQAGKVDFVDYKGQKAMRLAQNAGPVVLNEVIFQDGTIEFDLEPIRPESAQSIYFHRHDSNDQEIVYLRTNSTLNPLANDGIQYSPYVRGVNLWDLYPEYQAPALLKPGEWNHLKLIVSGNRLQVFLNQAPQAVLDIPQLESNSRQGSIAFEGASHIANLHVKPTIVEGVSPLASPDLTNHDANYLRTWAVSTPQELPDGHELSVRQLPTPEQFNDSIGAERRGLLNLTRKYGASKTRRVVWLQTTLVAQEAVSTNLQLGFSDEVWVFLNHQMVLVDKNVYQYNMRKYPDGRISTQNATAPLTLKTGQNDLLIGVANDFYGWGLMARLESTTHIQATGQVARILSLANELSSLDVSVYEGTYRNADVQFTLRFFKKGKRLQLQLSGPDPIDLQALGHHSFLYTASSATFDFDLGHKKVILRQGSDTRAFVKE
>NZ_CP025096.1|WP_100993340.1|8485378_8485780_-|hypothetical-protein
MKRRRPDSPKTQPSLSEKEPEHHRLDLLIHDLRNCISAIGFAQYFLNDKLDLSPHEQAAYQAILRSNLSQATGLMDQFLQAAPVLSKQANATAPNWTALLKHLSSQLPQAVAAESADQLAHLKKLVEIGLQSG
>NZ_CP025096.1|WP_100993341.1|8486165_8487455_-|serine-hydrolase
MIRVVIFFSLWLPPLFTSAQLTTSGLDSLFNRLAANQLAKGSIAITQNGELRYQRSVGSDQLAQTQFRVGSITKIFTAVLVYQLIEAHQLRLTDKLSRFFPDLANAHTITIAQLVGHRSGLASFTNNTDYDTWKDQPKTHAELLTMIKTQKPDFEPDARADYNNSNYLLLSYILEQLYRKPYKAIVTEKIIQPLALKHTYYGDHAGFQAQEAVSYKYVNQAWKADRAAYLDNFSGAGAILSTPGDLCQFITSLFSGRLISQQSLDTMKQMQDGYGKGLFPYGDALHPGYGHNGKTEGFAASLQYYPQSHLAIAYCTNGEVYPKAQILQHVFKACFGMADTLPTFKPIALTSPQLEPFTGRYGASSGMEVSNRLDSGKLLLSLKGQDFELTPIATNEFWNKAYGFFFRFANGGQQLMIHDVDAIYELTKR

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Crispr_ID: NZ_CP025096_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_13

8657438-8657538

Orphan

Consensus_repeat	Method
GCCCACGCGTCGAACTATCATTAAGCTGCTTTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025096_13

>merge|NZ_CP025096|13|8657438-8657538|CRISPRCasFinder
GCCCACGCGTCGAACTATCATTAAGCTGCTTTAAAGTGATGCGTGGGCGTAATCTGCACGACGAACGGCCCACGCGTCGAACTATCATTAAGCTGCTTTAA

>NZ_CP025096|13|13|8657438-8657538|CRISPRCasFinder
GCCCACGCGTCGAACTATCATTAAGCTGCTTTAA	AGTGATGCGTGGGCGTAATCTGCACGACGAACG
GCCCACGCGTCGAACTATCATTAAGCTGCTTTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100993485.1\|8658819_8659002_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993488.1\|8660948_8661236_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|193584
NZ_CP025096.1\|WP_100993483.1\|8655842_8656268_-\|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl\|CDD\|368576
NZ_CP025096.1\|WP_157816209.1\|8665000_8665546_-\|DUF4468-domain-containing-protein	unknown	unknown	gnl\|CDD\|213397
NZ_CP025096.1\|WP_170069485.1\|8645712_8649756_+\|tandem-95-repeat-protein	unknown	unknown	gnl\|CDD\|333740
NZ_CP025096.1\|WP_100993490.1\|8662421_8662691_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226202
NZ_CP025096.1\|WP_100993484.1\|8657103_8657424_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993487.1\|8660255_8660924_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|274396
NZ_CP025096.1\|WP_100990054.1\|8644779_8645007_-\|transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP025096.1\|WP_100993480.1\|8653369_8654109_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP025096.1\|WP_100993161.1\|8662711_8662903_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NZ_CP025096.1\|WP_100993489.1\|8661305_8662124_+\|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl\|CDD\|377136
NZ_CP025096.1\|WP_100993479.1\|8649715_8652346_+\|Ig-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|380078
NZ_CP025096.1\|WP_100993482.1\|8655221_8655647_+\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NZ_CP025096.1\|WP_100993486.1\|8659023_8660178_+\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP025096.1\|WP_100993491.1\|8663815_8664580_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|376885
NZ_CP025096.1\|WP_157816210.1\|8666451_8666760_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993476.1\|8644090_8644648_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367272
NZ_CP025096.1\|WP_100993481.1\|8654634_8655048_-\|response-regulator	unknown	unknown	gnl\|CDD\|381108
NZ_CP025096.1\|WP_157816208.1\|8645088_8645634_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993488.1\|8660948_8661236_+\|hypothetical-protein	gnl\|CDD\|193584	cd09895, NGN_SP_UpxY, N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), UpxY. The N-Utilization Substance G (NusG) proteins are involved in transcription elongation and termination. NusG is essential in Escherichia coli and is associated with RNA polymerase elongation and Rho-termination. Paralogs of eubacterial NusG, NusG SP (Specialized Paralog of NusG), are more diverse and often found as the first ORF in operons encoding secreted proteins and LPS (lipopolysaccharide) biosynthesis genes. NusG SP family members are operon-specific transcriptional antitermination factors. UpxY proteins, UpxY proteins, where the x is replaced by the letter designation of the specific polysaccharide (UpaY to UphY), are a family of NusG SP factors that act specifically in transcriptional antitermination of operons from which they are encoded. UpxYs are necessary and specific for transcription regulation of the polysaccharide biosynthesis operon. Orthologs of the NusG gene exist in all bacteria, but their functions and requirements are different. The NusG N-terminal (NGN) domain is similar in all NusG orthologs, but its C-terminal domain and the linker that separate these two domains are different. The domain organization of NusG and its orthologs suggests that the common properties of NusG and its orthologs and paralogs are due to their similar NGN domains.	2.89839e-25
NZ_CP025096.1\|WP_100993483.1\|8655842_8656268_-\|plasmid-mobilization-relaxosome-protein-MobC	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.000340578
NZ_CP025096.1\|WP_157816209.1\|8665000_8665546_-\|DUF4468-domain-containing-protein	gnl\|CDD\|213397	cd12190, Bacova_04320_like, Uncharacterized proteins similar to Bacteroides ovatus 4320. This model characterized a family of proteins conserved in Bacteroidetes, similar to B. ovatus ATCC 8483 reading frame 04320. Structurally, the protein resembles members of the SRPBCC domain superfamily (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC).	0.000519109
NZ_CP025096.1\|WP_170069485.1\|8645712_8649756_+\|tandem-95-repeat-protein	gnl\|CDD\|333740	NF012211, tand_rpt_95, tandem-95 repeat protein. This 95-amino acid repeat occurs in tandem in proteins that may be several thousand amino acids long.	2.72225e-15
NZ_CP025096.1\|WP_100993490.1\|8662421_8662691_+\|hypothetical-protein	gnl\|CDD\|226202	COG3677, COG3677, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.6679e-16
NZ_CP025096.1\|WP_100993487.1\|8660255_8660924_+\|sugar-transferase	gnl\|CDD\|274396	TIGR03023, Sugar_transferase., Undecaprenyl-phosphate glucose phosphotransferase. This family of proteins encompasses the E. coli WcaJ protein involved in colanic acid biosynthesis, the Methylobacillus EpsB protein involved in methanolan biosynthesis, as well as the GumD protein involved in the biosynthesis of xanthan. All of these are closely related to the well-characterized WbaP (formerly RfbP) protein, which is the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose (NOTE: not glucose) to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. Colanic acid biosynthesis utilizes a glucose-undecaprenyl carrier, knockout of EpsB abolishes incorporation of UDP-glucose into the lipid phase, and the C-terminal portion of GumD has been shown to be responsible for the glucosyl-1-transferase activity.	4.75232e-85
NZ_CP025096.1\|WP_100990054.1\|8644779_8645007_-\|transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.33491e-20
NZ_CP025096.1\|WP_100993480.1\|8653369_8654109_+\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	8.40394e-31
NZ_CP025096.1\|WP_100993161.1\|8662711_8662903_+\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	2.29403e-16
NZ_CP025096.1\|WP_100993489.1\|8661305_8662124_+\|WecB/TagA/CpsF-family-glycosyltransferase	gnl\|CDD\|377136	pfam03808, Glyco_tran_WecB, Glycosyl transferase WecB/TagA/CpsF family.	4.44526e-70
NZ_CP025096.1\|WP_100993479.1\|8649715_8652346_+\|Ig-like-domain-containing-protein	gnl\|CDD\|380078	pfam17963, Big_9, Bacterial Ig domain. This entry represents a wide variety of bacterial Ig domains.	1.15827e-11
NZ_CP025096.1\|WP_100993482.1\|8655221_8655647_+\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	0.000796261
NZ_CP025096.1\|WP_100993486.1\|8659023_8660178_+\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	5.1435e-63
NZ_CP025096.1\|WP_100993491.1\|8663815_8664580_-\|Fic-family-protein	gnl\|CDD\|376885	pfam02661, Fic, Fic/DOC family. This family consists of the Fic (filamentation induced by cAMP) protein and doc (death on curing). The Fic protein is involved in cell division and is suggested to be involved in the synthesis of PAB or folate, indicating that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism. This family contains a central conserved motif HPFXXGNG in most members. The exact molecular function of these proteins is uncertain. P1 lysogens of Escherichia coli carry the prophage as a stable low copy number plasmid. The frequency with which viable cells cured of prophage are produced is about 10(-5) per cell per generation. A significant part of this remarkable stability can be attributed to a plasmid-encoded mechanism that causes death of cells that have lost P1. In other words, the lysogenic cells appear to be addicted to the presence of the prophage. The plasmid withdrawal response depends on a gene named doc (death on curing) that is represented by this family. Doc induces a reversible growth arrest of E. coli cells by targetting the protein synthesis machinery. Doc hosts the C-terminal domain of its antitoxin partner Phd (prevents host death) through fold complementation, a domain that is intrinsically disordered in solution but that folds into an alpha-helix on binding to Doc.This domain forms complexes with Phd antitoxins containing pfam02604.	5.1149e-07
NZ_CP025096.1\|WP_100993476.1\|8644090_8644648_+\|hypothetical-protein	gnl\|CDD\|367272	pfam02956, TT_ORF1, TT viral orf 1. TT virus (TTV), isolated initially from a Japanese patient with hepatitis of unknown aetiology, has since been found to infect both healthy and diseased individuals and numerous prevalence studies have raised questions about its role in unexplained hepatitis. ORF1 is a large 750 residue protein. The N-terminal half of this protein corresponds to the capsid protein.	0.00837581
NZ_CP025096.1\|WP_100993481.1\|8654634_8655048_-\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.26041e-39

>NZ_CP025096.1|WP_100993484.1|8657103_8657424_+|hypothetical-protein
MKVVLLNTFILFCLTACSFDPLDQKYTEAIGLGPLLEVMPPISKTELGWIIMAKKANDEKKISNEGKTFRELSKQGHDITEAARAQSFVDSLNYKAQVEQRLKRRF
>NZ_CP025096.1|WP_100993483.1|8655842_8656268_-|plasmid-mobilization-relaxosome-protein-MobC
MKEKDKWYKGGRPEMKPEERATRVVQVRFTQAEYDQLLARKATVRTLTVSTYVRAVCLNKPLRLKPERSTYQDILLSLLRDTRSDVLRIGININQAARRINSTTDYQDLPREVTRMVSDMARFDAQLQEVMAAISKGSGEV
>NZ_CP025096.1|WP_100993482.1|8655221_8655647_+|response-regulator
MDTLKPWVALLDEDEDDYIFWQHGFRQWAQHLDLYWFSSVTEFLSATSLGKDKPVALVMDGVIPDGEEMKWLSTLLLHPSCRQACLLMLSAEVAEPQRADFLRLGASDHLQKPIRLDELQLVVSTVSSHVARKVGLPPSEL
>NZ_CP025096.1|WP_100993481.1|8654634_8655048_-|response-regulator
MHQNTYPCVFIADDDEDDRFLLNLAFARHSPRCRLVFAHDGLALLDALSSSKTTPELIILDLNMPRLNGLEALKVLRHQPLYQTTPIVMLTTSEADYDRQQAEQLGANEFITKPMNSELLGQLVTQLRVNWLEGNCC
>NZ_CP025096.1|WP_100993480.1|8653369_8654109_+|IS5-family-transposase
MRRYEITDQQWSKIALFLPGKVGDVGRSTVDNRLFVNAVLWIARSGAPWRDLPERFGPWNSVYRRFRRWAKADIWKNVFEELQEPDLDWLMIDSTIVRAHQHAAGPKKSDPASECLGQSVGGWSTKIDALGNPLRILLSVGQRADITQAEPLLTDYQTRAVLADRGYDADSFITYLHVHQTEVVIPAKKNRLEPRSIDENLYKDRNKVERYFNKLKQYRRVATRYEKTANSFAGFVYLASTMILLL
>NZ_CP025096.1|WP_100993479.1|8649715_8652346_+|Ig-like-domain-containing-protein
MISGLTASTSYTVSYSKNGAAAQTVVLTSTAAGAVTVTGLGQGSYQLTSLGTSNCTSAQTLPAVVLVDPAGPALAQNQVSGTNPTACNATTGSITLSGLTASTSYTVSYSKNGGSTVAIVQNSTAGGLFTISGLGQGNYTISNLGTNNCTSMLSLSAITLSDPAAPILSAASLVGTNPTTCGTATGSFSVTGLNANVSYTLSYEKDGGVVAPVSLISNALGVISVTGLATGSYGNFVLTNNLGCSTAPLVGPFNLSNPSLPTPTVATLTSVNASCGGNDGKLQLSGLTAGQTFVFHYQLGSIAQAKVAPVNASGILSVTGLSPGVYSDFYVTQGACISGTYPGPITLNANCLPPVVTPDIASTSPGKPVTGNVLTNDTDPNTSPTTGGQLTASLINQPAVGSVVLNPDGSYTYTPPTGFTGVTSFCYLATNTAGLSASTCVSIHVNPDPSPLANDAPIANNDNTQTTMGVAVTINAAANDTDPDSATSLNGQLNTPTILAQPSVGVASVVNGKFVYTPPANFTGVVSFPYSICDKATPALCATAVVTINVQPTPPVGTTLSPVAVDDALLTTKNTSATGTVAANDSDPNSPALPLTFTSGQPAHGTVVMGPNGTYAYIPVTGYSGPDSFTYLACNTAGKCDVATVTIDVQVPANLPPVLVGEPIVTDQGKPVTVCLPIVDGDVTDTHSVTVCGQPGNGVVTAQVNNTTHQVCLTYTPTPGFTGSTSVCITVCDAAGSCTTVLVPITVIPTSQTIALPQPPVVVVVPIVTPKDSTAQVCMTIVDPNMGDVQSVTLCSSPTKGSVTATVNNTTNQVCVLYKPTPGSVGPDAVCLLVCDQSGLCTQVTVPVTIVDPTPPGTTPVAPVVTPTPIVVTAAS
>NZ_CP025096.1|WP_170069485.1|8645712_8649756_+|tandem-95-repeat-protein
MKNHYAMVRYLAWLLSLSWLLLNSSAVNAQQSTNTIKYRVTYDASTQLYTAWVVPDYATPNSNNGGANELVSTAQVTLKVPMGFVIQNITDASGTQSWEKAPAKLGPNLSLTATNGTVFLQDYSPAVLDPAYAYYVIGKTPSESNLGTFVIGTPVALFTFKGNGCFGAIQPLPPGDPFIQASLDAYSFNVPNSFYSSSGQPQGGNQDPLEQFINISGAPANCFQPPIATPDIANTTVDKPATGNVLTNDTDPNAGPATGGPLTASLISQPSSGTVTLAPNGSYTYTPPTGFTGVVSFCYSVSNTAGLSASACVTVNVAPNPILAYNNPPVASNDNTQTTMGAAVTINAAANDTDPDNATSLNGQLSAPTILAQPSVGVASVVNGQFVYTPPANFTGVVSFPYSICDKATPALCATAVVTINVLATPPVGTTLSPVAIDDALLTTKNTSATGTVAANDSDPNSPALPLTYTSGQPTHGTVVMASNGTYTYTPTTGYSGPDSFTYLACNTASKCDVATVTINVLAPTVLPPVATPDIASTSPGKPVTGNVLTNDSDPQGLPLTASLLSPPTSGTVTLNPDGTYTYTPPTGFTGPASFCYSVSNTAGMSSSACVTVNVTPDPSVFANDPPVANNDNTQTTMGTSVTINVAANDTDPDSATSLNGQLNIPTILAQPSVGTASLLNGQFLYTPPANFTGVVSFPYSICDKATPALCATAVVTITVLPTPPVGTTLSPVAVDDALLTNVNTPKTGTVAANDSDPNSPALPLTYTSGQPVHGTVVMASNGTYTYTPTTGYSGPDSFTYLACNTASKCDVATVVIDVQAPMSAPPVVTPDIANTNMNTPVAGNVLTNDTDPQGGPLTASVTVQPTAGTVTMTPDGAYTYTPPTGFTGVVSFCYSTTNTAGLSAGTCVTINVNPDPSLTQNNKPIANNDNTQTTMGVAVTVNVAANDTDPDSTTSLNGQLNTPTILAQPAVGVASVVNGQFVYTPPANFTGVVTFPYSICDKATPALCATAVVAVNVQPTPPVGTTLSPVAIDDAVLTHTNTPVTATVAGNDTDPAGLPLTYTSGQPVHGTVVMASNGTYTYTPTTGYTGPDSFTYAVCNSAGKCDVATVSVDVQNSCLLPALATYDVNPFAPSACGGSDGYILLTSLPLSTSVTISYQKNGIVQTYAGLSDANGTLTIPNLLPATYGQFSFQTSSCISGVYSGTVAINEGAAPAAITASNLTKTNPTACASATGSITVGGLTASTSYTLTYSKNGGATQTVVATSNASGQISLTALTAGNYSVFTYQKTAGCPSTPSSSTLVLTDPAAPTIAQNQLTVGYEPNQLWNGNGNAVDQRPDGFDQLHG
>NZ_CP025096.1|WP_157816208.1|8645088_8645634_+|hypothetical-protein
MDSRPALVQRDGDIVEIDGTSAVAFSAVQGSYYVSVKHRNHLGVMTASAVPLSVTGTSVDFRTSATGTYRVTTSAINQSQVTVAQGVALWGGNVVYDKSVIYQGTTNDVSAIANQVKGPLNLTGAANYILNGYYTGDVNLDGRTIYQGNSNDVNYIYLNVTKNHPGNATGQNFFVIKEQLP
>NZ_CP025096.1|WP_100990054.1|8644779_8645007_-|transposase
MAKWHEKVRQAGFKTFNTVARSIQNHYETILNYFDNRSTNASAESFNAKIKAFRSQFRGVRNIEFFLYRLTQLYA
>NZ_CP025096.1|WP_100993476.1|8644090_8644648_+|hypothetical-protein
MTYPAKPFLVLGLITLLAGACSKDEQNVAPTNDNEAITTATLTLTNKATPTEIITATIDNLNTTADFSKATLLLKANTTYTGTISLLDKTQTPTLDATEEIREKTNEHLFVYTPSTGLGLTITLTDKDTNPSPGPYPVGLTTEMKTGAAGTGKLKVVLRHQPNVKNGTATPGSSDLDVDFSLMIQ
>NZ_CP025096.1|WP_100993485.1|8658819_8659002_+|hypothetical-protein
MASKSDKTLLLDTSQPETRKQVFEAIRALEGLYTTDLTRKRWRVGNGQRGYYWGYMVTAS
>NZ_CP025096.1|WP_100993486.1|8659023_8660178_+|polysaccharide-biosynthesis-tyrosine-autokinase
MKNTNAAISENIETIRQQLISNRNQLVANNQRMEGMIRTVPGKERALLNITRQQGIKNNLYTYLLQKREETALSAASRVSDSRIVDPAHTTSQPVKPVKLMIFALFAVVGLVIPIGVITAKDTVNNHVLRRSDVEEVTQIPIIGEVIKERQLGTESFVFKSRMHSVIGEQIRALRTNLLFLNGDAQKNQVILFTSSISGDGKSFMSLNLGASLALVNRKTVIVDMDMRKPKLHKSLHIENKLGLSNYLTGEADLDNLLHPIIGHENYYIITAGSLPLNPSELLSSPRLANLLQELKERFEYILVDSPPIGLVTDSQVIAPYADATIFVVRHDHTPKNYIKMVDALYKEQRFQKLSIVLNGVGKGESLSYSYNYGDYMDLTKKFD
>NZ_CP025096.1|WP_100993487.1|8660255_8660924_+|sugar-transferase
MLSLDSHYKTLYVYSELRANHNDFTYHQAGKRVFDICIASFVAITILSWLTPLLGLLIWIESPGPILYIQKRTGYRGSWFRCLKFRTMTHTPQATFKQAVKDDKRITRIGGFLRRTNLDEMPQFINVLMGDMSIVGPRPHALQHSAQFWNTMPNYRKRYRVKPGITGLAQIRGCRGETDQLIKMQHRVRYDRFYNRKRSIAFDIWICWSTAKSMVEGNVNVW
>NZ_CP025096.1|WP_100993488.1|8660948_8661236_+|hypothetical-protein
MPWYVLYTKSRNEKIVAEKLLEQGINVYCPLIKTKRKWSDRIKLVEESHYRSYCFVDLEEKKRATVFGIIGIVRYLFWQNKPAVVCDFEIEAIKD
>NZ_CP025096.1|WP_100993489.1|8661305_8662124_+|WecB/TagA/CpsF-family-glycosyltransferase
MFTNLLPQPHNKTKINFPDKYDISSKYSTVISLNIRRGSSKQIQEEVIVAAQQRRSSTVCFANVHMTIEATRDKEYANIVNGSDWVLADGAPIKWAIQAIHKHKQERITGYSFMQNILLQSAEDGLSVFFYGGTQEMLSATISMCNKMYPSLTVAGVYSPPFRSLTIVEEDEIIERIKLSGAQLIFVALGCPRQEIWINRMRHQIPAVLLAVGGALPVFAGQFSQAPHWVQLSGFEWLFRLCQEPSRLFRRYMITNTLFVIYLFRVLFKKRH
>NZ_CP025096.1|WP_100993490.1|8662421_8662691_+|hypothetical-protein
MVLEAVSCKHCGQTKHVKRYGTTRAGTQRYRCYDCGRTFVQTYTHKARDPLVKEQITQMVLNGAGIRDTARVLGVNRNTVSAQFKKLAS
>NZ_CP025096.1|WP_100993161.1|8662711_8662903_+|ATP-binding-protein
MEDRYGRHSTIITSQLPVAQWYDYLAEPTIADAFLDRLLHQAHRIELKGESQRKQGKGEEKSV
>NZ_CP025096.1|WP_100993491.1|8663815_8664580_-|Fic-family-protein
MKANLPLATLPQLIDRFQAAAINTNGQTLDPLILLAYHSTAIDGAGLTLPQTKTLIQTGNLLDDHRQTDQLMIIDYHYTLGQILTMATHHEPLSQLTCQQLAANLMRQTGGPLHSLLSTIDTRKGELRIDNALAGRGGLVGAHKLPVALAELLKDINTRINQLKTPRQLYDLSFQAHFHLLSLHPFGAGNGRMARLLMSYIQQYHGVPLSFVYADQSRLYFDAIEASWRQKTSVPIVSFLHSQLSRYLEEVIER
>NZ_CP025096.1|WP_157816209.1|8665000_8665546_-|DUF4468-domain-containing-protein
MIQGPVNLYAQAQTYQSFIYQLVPIDGESGDIVYLAVVPVRGASRTQLYNRAHHFMTHTLRTGSLLPMAHGAKHHINRCGIITLQHAQAGSTTPQDYRVTVELRVKAGRYRYRLSQFRAQRDSVGHGLPIRELYQCDKKTYAYDESTAQQLRTWDRSVKAYLGQLHKYMTDSQETDYYRPL
>NZ_CP025096.1|WP_157816210.1|8666451_8666760_+|hypothetical-protein
MANQTPEQVFKGKDRSTNRVKITNNKQFRYSIKWSGLRGAVCEDVQRWPTLHWLNTVKGNFKMLLEFLSSIFQQVQTLATRVSVLALQNVKTICASVNIILS

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Crispr_ID: NZ_CP025096_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_14

8693432-8693519

Orphan

Consensus_repeat	Method
GCACCTTCGGGTATTGAAATTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025096_14

>merge|NZ_CP025096|14|8693432-8693519|CRISPRCasFinder
GCACCTTCGGGTATTGAAATTATCGGGCATGATACGCCAATTAAGGGAATTCTCAAGTCTCAATCGCACCTTCGGGTATTGAAATGTA

>NZ_CP025096|14|14|8693432-8693519|CRISPRCasFinder
GCACCTTCGGGTATTGAAATTAT	CGGGCATGATACGCCAATTAAGGGAATTCTCAAGTCTCAATC
GCACCTTCGGGTATTGAAATGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_157816215.1\|8693280_8693430_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816214.1\|8689408_8689969_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816216.1\|8698875_8699073_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816217.1\|8703633_8703936_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993517.1\|8704275_8705295_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379352
NZ_CP025096.1\|WP_100993512.1\|8700986_8701412_+\|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl\|CDD\|368576
NZ_CP025096.1\|WP_001802007.1\|8686640_8686733_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816213.1\|8687563_8687713_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993514.1\|8702185_8702599_+\|response-regulator	unknown	unknown	gnl\|CDD\|381108
NZ_CP025096.1\|WP_100993503.1\|8684836_8686150_+\|plasmid-recombination-protein	unknown	unknown	gnl\|CDD\|366451
NZ_CP025096.1\|WP_100993502.1\|8684005_8684620_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993515.1\|8703070_8703382_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993511.1\|8699565_8700219_+\|antA/AntB-antirepressor-family-protein	unknown	unknown	gnl\|CDD\|226091
NZ_CP025096.1\|WP_100993507.1\|8690759_8691176_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993510.1\|8693711_8693993_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379154
NZ_CP025096.1\|WP_170069486.1\|8698031_8698769_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197912
NZ_CP025096.1\|WP_100993504.1\|8688181_8688760_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993506.1\|8690195_8690648_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993513.1\|8701581_8702007_-\|response-regulator	unknown	unknown	gnl\|CDD\|333815
NZ_CP025096.1\|WP_100993508.1\|8692928_8693255_-\|transposase	unknown	unknown	gnl\|CDD\|315923

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993514.1\|8702185_8702599_+\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	5.0939e-39
NZ_CP025096.1\|WP_100993511.1\|8699565_8700219_+\|antA/AntB-antirepressor-family-protein	gnl\|CDD\|226091	COG3561, COG3561, Phage anti-repressor protein [Transcription].	8.31273e-08
NZ_CP025096.1\|WP_100993503.1\|8684836_8686150_+\|plasmid-recombination-protein	gnl\|CDD\|366451	pfam01076, Mob_Pre, Plasmid recombination enzyme. With some plasmids, recombination can occur in a site specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre. Pre is a plasmid recombination enzyme. This protein is also known as Mob (conjugative mobilisation).	4.107e-31
NZ_CP025096.1\|WP_100993517.1\|8704275_8705295_-\|hypothetical-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	0.00847734
NZ_CP025096.1\|WP_100993510.1\|8693711_8693993_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379154	pfam13384, HTH_23, Homeodomain-like domain.	4.9542e-05
NZ_CP025096.1\|WP_170069486.1\|8698031_8698769_+\|hypothetical-protein	gnl\|CDD\|197912	smart00844, GA, GA module. The protein G-related albumin-binding (GA) module is composed of three alpha helices. This module is found in a range of bacterial cell surface proteins. The GA module from the Peptostreptococcus magnus albumin-binding protein (PAB) shows a strong affinity for albumin.	1.07467e-08
NZ_CP025096.1\|WP_100993512.1\|8700986_8701412_+\|plasmid-mobilization-relaxosome-protein-MobC	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.00128805
NZ_CP025096.1\|WP_100993513.1\|8701581_8702007_-\|response-regulator	gnl\|CDD\|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	0.000136536
NZ_CP025096.1\|WP_100993508.1\|8692928_8693255_-\|transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.64569e-10

>NZ_CP025096.1|WP_157816215.1|8693280_8693430_-|hypothetical-protein
MRQKGQGRKPILNLTNSLHQQALSRAVTAHYQDAERIKADLQTALGLAS
>NZ_CP025096.1|WP_100993508.1|8692928_8693255_-|transposase
MYLFFLPTYSPHLNPIEILWRFLKYRWLQKLHYSSWSRLKKAVFAIIRLFGQEYRICFDGLVNRNKVKGSNLNQIAHKAHADGIRSIALEAHRLLQQLSQLLDKPADV
>NZ_CP025096.1|WP_100993507.1|8690759_8691176_+|hypothetical-protein
MIINEPNSDQNPLKVGQTKTPESPTPLKTGRPTRDTLEPARWTIRGIETDTRLTIEKAAERSGKTLGQFFNIELREAAANVLKKEHQPPARGEDLASDLFEKIKTELRESQAAELQSIREAIERRPASLREWLFGKRS
>NZ_CP025096.1|WP_100993506.1|8690195_8690648_+|hypothetical-protein
MRLLLLLLCISFGVLACDPPTDTKLKLINASDKPVLIIYNTEGKNHDINGLSGDYNPFHEIHRADSTRGYQIGLMKDNPNYILPGDTIAAQLGVGKWENHIGNGKLWVYVFKPETVLDNDWDGIRMGQKWDKVYSLTLDQVKAKNWVINL
>NZ_CP025096.1|WP_157816214.1|8689408_8689969_+|hypothetical-protein
MNLTTTRAIFRPIWHVPYFLLTTMAVFLTFFLHGFAHWLVGKYLGEEITINFNPAHTIDQAYGQEGNQLPIILAGPVFTLLQAIYFFYVMKRGRDTILYPFLLAPVMMRVLAGIMNFVNPNDEGLVSLSVGLGLFTLPVLTCIFLLYLVFKTSVSYQMEIKFNLQIIALVLVISLFLILLNQYSVR
>NZ_CP025096.1|WP_100993504.1|8688181_8688760_+|hypothetical-protein
MKSTYRKVNEHGLNKVNPFLDDTVQHIEKGEKTLLFGQKNPDLIIDSDSQVKGHSLFARKVTVDKAKFMKVFMSGLSNWFDLSKAGIKMFAYVANQVTPNKDTFDVDFDECKAFTGYKGTSTILSALAELMENKFIARGPNPYKYYINPTIFFNGDRLTFIEQYEVESKEENSLEIGKTPQESFNELAKTLA
>NZ_CP025096.1|WP_157816213.1|8687563_8687713_+|hypothetical-protein
MRRSRLNYEKVKPPNSNPFEKLLKEDRPAYGNGCSANAHNVPAQSSLIE
>NZ_CP025096.1|WP_001802007.1|8686640_8686733_-|hypothetical-protein
MENIFKIELMNGICRSENMNMKKKNKGEKI
>NZ_CP025096.1|WP_100993503.1|8684836_8686150_+|plasmid-recombination-protein
MKAVCRVAKVKGAGSIGGKSDHNYRQGHVPNADAERRHLNHEYVLNYENLAKAIEAKLHHAGLDHVRKDAVKGMEFILTASPEAFKRDQTGQFTGDYRESDWVKANLEFMKQQYGSNLVAFTLHQDEKTPHIHAIVVPITPDKRLCAKELFTPKTLRQLQTDYAAAMKPFGLERGIEGSRAQHVDMKHIYGLQQQERQTIEKNLQPIQTINAPLAIDKPGPLDLLNLERWKQQQEAKINAELNRRLEEIKQAAEKALKAAVANATAKEQEKVLAQRLTTSEGLKQTNFEKAKKTGEELATTTSKINQIAVLLDEKRLNPKWSEGLAGHLRSKVLPQMEADILECLKERLTDGNDLNPRLEKKGYKIVKDAKGTFYLTDPKTEVRLNLITAQIKGEFLSELVHETVQRGIKEAQQEKEKKAQKSEVKNNQDQGYKFRR
>NZ_CP025096.1|WP_100993502.1|8684005_8684620_-|hypothetical-protein
MSLLSRLFGEENKNIVPINFTKYPEIGSLTSLELSHYNKMIQMLNNSLDDYKIFHKTEFKKEPSRAKLLEMTAFTWALTEPIFQQNGLSQKAGFSLYHSVREAFINLSKEIVDAGNQDYDTFFQNRVGFYTDRIEELFKKGRSNYGTYGSLNDLITVRPLLFIPNNDPLKIYTLIVGVDVVMRFTKFITDSIIKQTSNVRSALA
>NZ_CP025096.1|WP_100993510.1|8693711_8693993_+|helix-turn-helix-domain-containing-protein
MSDTEKLTLQEAIKNHPKYEFRRACQALLWSHKGFSAKEVAGHTEVSQHSVGKWLSAWQELGLVGLMRQKGQGRKPILNLTNSLHQQALSRAS
>NZ_CP025096.1|WP_170069486.1|8698031_8698769_+|hypothetical-protein
MHSLQNGINDETQTKQTQKYLDAEPSKKSAYDQAVNAAKAILTKASGQNVDKAEVEQALQNVNSTKTALNGDAKLNEAKAAAKQTLGTLTHINNAQRNALDNEITQATNVEGVNTVKAKAQQLDGAMGQLETSIRDKDTTLQSQNYXDADDAKRTAYSQAVNAAATILNKTAGGNTPKADVERAMQAVTQANTALNGIQNLERAKQAANTAITNASDLNTKQKEALKAQVTSAGRVSAANGVEPS
>NZ_CP025096.1|WP_157816216.1|8698875_8699073_+|hypothetical-protein
MKAGIERTVNQKGLPSLAAPVNPIQLRPAYLHDHSDIKSKPEHPEHYESPWQQLHLYLLMWRLKC
>NZ_CP025096.1|WP_100993511.1|8699565_8700219_+|antA/AntB-antirepressor-family-protein
MYEVCTTLAHWSKKNIVNNQFDQENVDWIILDIMSSSNNGSMTTDYELTFDFAERLSMVAQTDKGEEIRRWFQSLKKKVEALPASQDDLILMLAQRNVETAKRLSVIEERLDRFEQIQQTAATELLALPAPTEPMAEIPTESQIIRLVNSYSQAKSVAQPEVWRKLYTELLYRYRISVNAYKRPPGESKIQMLKRVGHLDKLYVVATNVLQMPQANA
>NZ_CP025096.1|WP_100993512.1|8700986_8701412_+|plasmid-mobilization-relaxosome-protein-MobC
MKEKDKWYKGGRPEMKPEERATRVVQVRFTQAEYDQLLARKATVKTQTVSTYVRAVCLNKPFRLKPERSTYQNILLSLIQETRSDVLRIGVNVNQAARRINSTTDYQDLQREVTKMASDMARFDAQLREVMATILQQGGET
>NZ_CP025096.1|WP_100993513.1|8701581_8702007_-|response-regulator
MEILKPWVALLDEDEDDYIYWQHGFRNWAQHLDLYWFSSVTEFLSATSLGKDKPVALVMDGVVPDGEEMKWLSTLLLHPSCQQACLIMLSTEVTEPQREAYLRLGASDHLQKPVHLDELRIVVSTVSGHITRKSGLQRSEL
>NZ_CP025096.1|WP_100993514.1|8702185_8702599_+|response-regulator
MNQHTYPCVFIADDDEDDRYLLNLAFTRHSPQCRLVFTYDGLDLLDALARYETSPELIILDMNMPRLNGFEALQALRQQPSYQSTPIVILTTSEAETDRQRAEQLGANEFITKPLKGELLGQIVARLRVDWLEGNCC
>NZ_CP025096.1|WP_100993515.1|8703070_8703382_+|hypothetical-protein
MQPDDVKTSLTYQIKEFLTYTADTDNDTIMAQYTLIEGLVDRSVIGDHLKFDVYNMGFGQENNADYAYFLHVNTVSSQPVERKGFALEGLQERMRRLLKELLA
>NZ_CP025096.1|WP_157816217.1|8703633_8703936_-|hypothetical-protein
MSTIRMNKEQRARLTAELKEFDQLDSGSQVQSITDAYNALLSTIQGIMLNSENPDGHDRAWSLLKDDAFKDLAAIQEGKLDALKDLKTKINRIGQLLLKP
>NZ_CP025096.1|WP_100993517.1|8704275_8705295_-|hypothetical-protein
MSDTTNVQKNKLTKEQKKLIYDSLATNIVRFQEYRLSSNKEPEINPETGQPRKRDSLKPDGAIFFEYLCYNSFKLYIEEQTSNGYFYHSYERIEDEYGIGKERVQKITNYLKSLGIVETKVCGFPKNTHYRVRFDNLAKIEVLIHLFRTKPDRTNEIAAHFASIAKIVKLRIETDQEAIEKQYVAEMSWFNHLKKIFYDERAKFNKTVPANAAIKKIQPKPRENTLRNINSGTYLVYYDPEGKERSEQEVDEYQKDFINGFRLYCAIYFLFTCEQSSTNRNLLALAEGDYISTLVNYASGIRDPIAYFFANSEGDLNFIMIDMIDGARQLDMTKGYFSN

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Crispr_ID: NZ_CP025096_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025096_15

8771346-8771438

Orphan

Consensus_repeat	Method
TGTTTTTTCGCTTATCAAACCTGTTTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025096_15

>merge|NZ_CP025096|15|8771346-8771438|CRISPRCasFinder
TGTTTTTTCGCTTATCAAACCTGTTTTTTCAACTTATCAAACCTGTTTTTTAGCTTATCAAACCTGTTTTTTAGCTTATCAAACCTGTTTTTT

>NZ_CP025096|15|15|8771346-8771438|CRISPRCasFinder
TGTTTTTTCGCTTATCAAACCTGTTTTTT	CAACTTATCAAACCTGTTTTTTAGCTTATCAAACC
TGTTTTTTAGCTTATCAAACCTGTTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025096.1\|WP_100993646.1\|8777351_8778002_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|222854
NZ_CP025096.1\|WP_157816228.1\|8776116_8776410_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993636.1\|8769152_8769779_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993641.1\|8771869_8772172_+\|integration-host-factor-subunit-beta	unknown	unknown	gnl\|CDD\|259858
NZ_CP025096.1\|WP_100994193.1\|8774907_8775018_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|349956
NZ_CP025096.1\|WP_100993637.1\|8769831_8770044_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993638.1\|8770015_8770315_-\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|367913
NZ_CP025096.1\|WP_100993642.1\|8772381_8773584_-\|DUF4249-domain-containing-protein	unknown	unknown	gnl\|CDD\|379442
NZ_CP025096.1\|WP_157816227.1\|8774603_8774768_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993631.1\|8766201_8766618_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993645.1\|8776623_8777268_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NZ_CP025096.1\|WP_100993644.1\|8775022_8775952_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993630.1\|8765424_8766012_-\|outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|372635
NZ_CP025096.1\|WP_100993647.1\|8778007_8778328_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993639.1\|8770307_8771264_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP025096.1\|WP_157816226.1\|8768072_8768270_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993643.1\|8773916_8774183_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_157816225.1\|8765018_8765378_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025096.1\|WP_100993635.1\|8768266_8769151_+\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NZ_CP025096.1\|WP_100993633.1\|8767626_8767983_+\|plasmid-mobilization-relaxosome-protein-MobC	unknown	unknown	gnl\|CDD\|368576

Protein	Function_ID	Function_description	E-value
NZ_CP025096.1\|WP_100993646.1\|8777351_8778002_+\|AAA-family-ATPase	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	2.92554e-45
NZ_CP025096.1\|WP_100993630.1\|8765424_8766012_-\|outer-membrane-beta-barrel-protein	gnl\|CDD\|372635	pfam13568, OMP_b-brl_2, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	0.000969232
NZ_CP025096.1\|WP_100994193.1\|8774907_8775018_-\|hypothetical-protein	gnl\|CDD\|349956	cd18083, aTrm56-like, archaeal tRNA (cytidine(56)-2'-O)-methyltransferase Trm56. Archaeal tRNA (cytidine(56)-2'-O)-methyltransferase Trm56 catalyzes the 2'-O-ribose methylation of cytidine at position 56 in tRNAs. Trm56 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	0.00339953
NZ_CP025096.1\|WP_100993639.1\|8770307_8771264_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	7.77061e-48
NZ_CP025096.1\|WP_100993638.1\|8770015_8770315_-\|BrnT-family-toxin	gnl\|CDD\|367913	pfam04365, BrnT_toxin, Ribonuclease toxin, BrnT, of type II toxin-antitoxin system. BrnT is a ribonuclease toxin of a type II toxin-antitoxin system that exhibits a RelE-like fold. The antitoxin that neutralizes this toxin is pfam14384. BrnT is found in bacteria, archaea, bacteriophage, and plasmids. BrnT-BrnA forms a 2:2 tetrameric complex and autoregulates its own expression, which is induced by a number of different environmental stresses. Expression of BrnT alone results in cessation of bacterial growth which can be rescued after subsequent expression of BrnA.	1.47977e-15
NZ_CP025096.1\|WP_100993645.1\|8776623_8777268_+\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	2.35864e-37
NZ_CP025096.1\|WP_100993641.1\|8771869_8772172_+\|integration-host-factor-subunit-beta	gnl\|CDD\|259858	cd13836, IHF_B, Beta subunit of integration host factor (IHFB). This subfamily consists of the beta subunit of integration host factor (IHF) and IHF-like domains. IHF is a nucleoid-associated protein (NAP) that binds and sharply bends many DNA targets in a sequence specific manner. It is a heterodimeric protein composed of two highly homologous subunits IHFA (IHF-alpha) and IHFB (IHF-beta). It is known to act as a transcription factor at many gene regulatory regions in E. coli. IHF is an essential cofactor in phage lambda site-specific recombination, having an architectural role during assembly of specialized nucleoprotein structures (snups). IHF is also involved in formation as well as maintenance of bacterial biofilms since it is found in complex with extracellular DNA (eDNA) within the extracellular polymeric substances (EPS) matrix of many biofilms.	2.42854e-26
NZ_CP025096.1\|WP_100993642.1\|8772381_8773584_-\|DUF4249-domain-containing-protein	gnl\|CDD\|379442	pfam14054, DUF4249, Domain of unknown function (DUF4249). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 279 and 365 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	1.22614e-30
NZ_CP025096.1\|WP_100993635.1\|8768266_8769151_+\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	2.43791e-15
NZ_CP025096.1\|WP_100993633.1\|8767626_8767983_+\|plasmid-mobilization-relaxosome-protein-MobC	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	0.00496887

>NZ_CP025096.1|WP_100993639.1|8770307_8771264_-|replication-initiation-protein
MNQAVEVRQHNAITNARYEYSEMQLDIFLYLLAKLRKDKSDGIYEVSVIEMGKLTGKKYNYQQLRIATEGMGSRMFEVSTPKSYIQLWMFQRIEYVHGTGIIEVEFANPIKPYLFDLKDNFTSFQLYAALRLSSKFAKRIYTICSQWKDKGQTQTFSLDELKKMLSLLDDKGNEQYRQIGQLKQFVLDESVKQINQHTDLKIGYTLEKKGRSFKNITFTVKAQPLAVVLPVENGAVKTGANLTGVSDAQYQNVRLLLEKWNIKRADVVNQIMNSADLIQEVNKFAYELQTGKVKVEKNVAGYLLTRLGLKQPKGIKND
>NZ_CP025096.1|WP_100993638.1|8770015_8770315_-|BrnT-family-toxin
MIEFQWDMGNENHIIDHYPLRANTIEEVESLFYDPAPLALRDPQHSDQEERFKLVARSNQNRILLVVYVIRNGQIRPISCRPANQKEREHYAQIAQKPQ
>NZ_CP025096.1|WP_100993637.1|8769831_8770044_-|hypothetical-protein
MLKSLKNPNKRTASEAAPKLIAVIKNGMTEQEMNESGEHWVNHKGPYMTVAETLAYAAERDKILAGKKQP
>NZ_CP025096.1|WP_100993636.1|8769152_8769779_+|hypothetical-protein
METKKAQSSDELVSELLQGVLDDIKGLKQSVNQLATKDEPDYREELKTLARAVESLKHQPGPASSESNQVFERFSRLEQLIRQKPDYKVSQYVRYGGYVFGLMVMLVAGLTWLALDWKGERDRFRDAYWTADWRVRYVKQADPTFYSHVEGVFTKDPAGVSKWIVEQEQADEKRALAVQAAEQAKALSRQANELEGKQMTKGKKKESQ
>NZ_CP025096.1|WP_100993635.1|8768266_8769151_+|relaxase/mobilization-nuclease-domain-containing-protein
MIAKTSIGRSFKGCCAYNMQKVEMGQGQVLLSQGVRDYELRAMVADFTRQAKMNPELTRSVWHTAISFDPQDEARLQLKPELMNQVASEYLKGMGLDQSQYVVIQHQDTAHSHFHIIANRVASNGQSISDSHNYNRSEKLLREIEQKHSLTLMKEQGYRLSLEHLPERDRHRLEMRNEVRQSLERSTTSAELKADLAQRGIEVIVNRDQAGKARGLSFERVSQTDNGEEIKVAFKGSKLHQSLSLCHIQEQLLENGHKRALELSQQRELAKAQELTISLQNEEKRLKKGRGLSM
>NZ_CP025096.1|WP_157816226.1|8768072_8768270_+|hypothetical-protein
MLNFLNPIPILEHREYNLLKAGDRIEFDALFEAWEMIDELEFYRAYKRATASDFRLYVNGKPLPL
>NZ_CP025096.1|WP_100993633.1|8767626_8767983_+|plasmid-mobilization-relaxosome-protein-MobC
MNPTEPLKKKGGRPPSTQKRDQQMTVLLTKLEKLAIQKRAEKAGLNLSDYGRQIILTGKAQARLSPEENATLNQVARLGSNLNQIAHKAHADGIRSIALEAHRLLQQLSQLLDKPADV
>NZ_CP025096.1|WP_100993631.1|8766201_8766618_+|hypothetical-protein
MLNEERTDTAKLFYFVLFVAVNGLSCLIIPFFLDYAHIYLNGFLIPDSLRWDDNNRLRANPIGWFTAQVLIVLIEFVGSLWLLYRFNWRNTPVWLARQPIRIIQGVSGLVVAVVTVVSLFGRGGFLIWLVKHYVKTVV
>NZ_CP025096.1|WP_100993630.1|8765424_8766012_-|outer-membrane-beta-barrel-protein
MRYLLFLIAIVFGNSYQSSAQSKNQFNIGAGYSYSNTIVSIENTALIGLAPIKAKPGFYVSLAYDHQLSRLFTTQIELNLQQKGHRYENPIEQQLVPVRYTYIGIRPTIGVKPVKKLSFLIGPELNWLISKSASWSNSKPIEIGLTGRGRYQFSRVGITGGYFRALTFYDLSGSGTYSFTNQNWQVGLFYQLSPR
>NZ_CP025096.1|WP_157816225.1|8765018_8765378_+|hypothetical-protein
MKTYCHAPKVTIRAVENDSLPSESYRVGVKFVFETYFKDTVSIYVDELCVAKKHLKSSSNGFAAAIDVRVHPSQEILLKTDRGECTQFILKRGYKYLYIGRSDNNNWTLAYSNYLWGYY
>NZ_CP025096.1|WP_100993641.1|8771869_8772172_+|integration-host-factor-subunit-beta
MTKQDVINQVSEKTGVDPLLTRSVIESFFTVVKESLVEGEPIYIRTFGSFILKQRAQKTARNISQNTAVTIPTQIIPSFKPGSEFTNQVRAQPMPAKIKK
>NZ_CP025096.1|WP_100993642.1|8772381_8773584_-|DUF4249-domain-containing-protein
MRLTFTLIIGCLAVLFLPLACVDPEDILLHGTVNVLVVDGTITNLAEPQMIRINRSKADPLTGRFGTTPITKAQVQVVVDSTQMIDCHETQDGTYQLPSDFKGQIGHAYQLRFTLSDGTRYQSTTEVMASVPPFDHLSAQFNPNSLEPAQRLAGNYAAAHDFYLDTQDPVETRNYYRWSWVLWEKQDWCRTCENAVYLIWDPSDTYLYENCYDVSQLIRGQYFVYDYACRTQCWDIFYSPDINVFSDQLTNGGPILHRRVAQIPFYDHNGALVEIRQTGLTQSAYTYFKLFQDQTQNTGGLADTPAAAPIGNVHNVANRQEAVVGYFTAGAVFAQRYWLDRKDSEGIPPGLFELVHGRVPQPEPVPSLVYIYSKYYVRPPTAVCVSSDSRTPSKPVGWQD
>NZ_CP025096.1|WP_100993643.1|8773916_8774183_+|hypothetical-protein
MYIKRLQRNKKNRNSLIFKRRIVEVYRAEIAQPADIQRYLHISLTELRQLNRWYFRHRLAPYLYPHKAYKAMKKHNQDAYVKALERRF
>NZ_CP025096.1|WP_157816227.1|8774603_8774768_+|hypothetical-protein
MTTPSKIQIRQFEILLDPNSPVLFGAGIVDHSFGLDALLHIADVTFPVFIGVDN
>NZ_CP025096.1|WP_100994193.1|8774907_8775018_-|hypothetical-protein
MQNNTQNFNIVLTKKVDLQIYKRCDFNVCIGNRPMI
>NZ_CP025096.1|WP_100993644.1|8775022_8775952_-|hypothetical-protein
MSDIIQFPNSSKKLYKDIKRAEQDQNYDLMYEYIVQYERQFELTEVIAMMKCRMLYETGSFLELREETIVLLKTGIQQYDALMIYYVKSLIGLGQYFEAVEVIHQIIDEVKDHKKRMALHPLKEFAKSKLIEDEKRLTQSLTDFDTLSMREQTHLILKLIDNGHFQFQETVLYILKSNTYSYNLISLMIEYLRFANCTQELTIEKYGMDVTFVPANLNGLEHTTLKEKVIPNVMETLNDGALHIAEEAHHIMNNHSIMIYPIDIETLFETNKWINAYECYFKNMLGLKCELQSIDAFNFIQQLDLNNNS
>NZ_CP025096.1|WP_157816228.1|8776116_8776410_+|hypothetical-protein
MPTDWVEIVNAREFDNNAYPGITADIVAEFSSILVELHKLTFRDYFHRNLSFKQLFSHFELHLNKEISKIILRDNTSIHNRKLADLLYLVKCELSLL
>NZ_CP025096.1|WP_100993645.1|8776623_8777268_+|recombinase-family-protein
MKKAIAYYRVSTDRQGKSGLGLEAQAEAVSNFAEREGYEVVAIFTETESGKKSQRPELLAALAQCRKERATLVIAKLDRLSRNVAFISNLMESRVDFKAVDNPHANRLMVHLLAAFAEHEREQISTRTKDALAAAKRRGVQLGKHGKEILSQVNATAAVEFATRLRPTIEHLQATGFTTVRAIRDELNRQQIPTYRAGSKWHIPNVYAVLKRLE
>NZ_CP025096.1|WP_100993646.1|8777351_8778002_+|AAA-family-ATPase
MIFTVGGIKGGTGKTTISTNLAVWLSQRGADVLLVDADEQESASDFTAWREETRKGQLGYTLVQLNGPTVRRQIEQLRPKYDHIVIDTGGRDTASQRAALFVSDIYLIPFAPRSYEIWTLSKVQALLSEIQGSRSIPLQVYSFLNKADTRGADNNEATEVLRENEELNFVDYPVINRKAFATAASKGLSVFEMMPIDEKAVTEVEALFSHVTGIKK
>NZ_CP025096.1|WP_100993647.1|8778007_8778328_+|hypothetical-protein
MAVSPPPKKVAPAKVDVQQTTKGQEKKIEDIINRGSTTVGQAEPQDQIKNFNIKIMSSQLTEVDQLRAKRPRKPTSPKLGVSLQDWIIEAIEEKIQREKKKYSAGE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP025096_3	3.1\|4674607\|27\|NZ_CP025096\|CRISPRCasFinder	4674607-4674633	27	NZ_CP033579	Vibrio mediterranei strain 117-T6 plasmid unnamed, complete sequence	33637-33663	6	0.778
NZ_CP025096_3	3.1\|4674607\|27\|NZ_CP025096\|CRISPRCasFinder	4674607-4674633	27	MK249133	Blackfly microvirus SF02 isolate 017, complete genome	4318-4344	6	0.778
NZ_CP025096_6	6.24\|7327224\|35\|NZ_CP025096\|CRISPRCasFinder	7327224-7327258	35	NZ_CP022220	Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence	19519-19553	8	0.771
NZ_CP025096_6	6.24\|7327224\|35\|NZ_CP025096\|CRISPRCasFinder	7327224-7327258	35	NZ_CP030052	Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence	611554-611588	8	0.771
NZ_CP025096_6	6.24\|7327224\|35\|NZ_CP025096\|CRISPRCasFinder	7327224-7327258	35	NZ_CP030054	Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence	791147-791181	8	0.771
NZ_CP025096_6	6.132\|7327225\|35\|NZ_CP025096\|PILER-CR	7327225-7327259	35	NZ_CP022220	Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence	19519-19553	8	0.771
NZ_CP025096_6	6.132\|7327225\|35\|NZ_CP025096\|PILER-CR	7327225-7327259	35	NZ_CP030052	Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence	611554-611588	8	0.771
NZ_CP025096_6	6.132\|7327225\|35\|NZ_CP025096\|PILER-CR	7327225-7327259	35	NZ_CP030054	Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence	791147-791181	8	0.771
NZ_CP025096_2	2.36\|2330112\|35\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2330112-2330146	35	NC_048068	Microbacterium phage OneinaGillian, complete genome	59228-59262	9	0.743
NZ_CP025096_6	6.6\|7326042\|35\|NZ_CP025096\|CRISPRCasFinder	7326042-7326076	35	NZ_CP024036	Bacillus aryabhattai strain K13 plasmid unnamed1	5989-6023	9	0.743
NZ_CP025096_6	6.17\|7326764\|35\|NZ_CP025096\|CRISPRCasFinder	7326764-7326798	35	NZ_CP042276	Agrobacterium tumefaciens strain 186 plasmid pAt, complete sequence	268170-268204	9	0.743
NZ_CP025096_6	6.114\|7326043\|35\|NZ_CP025096\|PILER-CR	7326043-7326077	35	NZ_CP024036	Bacillus aryabhattai strain K13 plasmid unnamed1	5989-6023	9	0.743
NZ_CP025096_6	6.125\|7326765\|35\|NZ_CP025096\|PILER-CR	7326765-7326799	35	NZ_CP042276	Agrobacterium tumefaciens strain 186 plasmid pAt, complete sequence	268170-268204	9	0.743
NZ_CP025096_10	10.9\|8413171\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8413171-8413207	37	MK962634	Achromobacter phage vB_AxyS_19-32_Axy16, complete genome	21598-21634	9	0.757
NZ_CP025096_10	10.22\|8414023\|35\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8414023-8414057	35	JX469828	Uncultured bacterium plasmid pRSB223, complete sequence	1086-1120	9	0.743
NZ_CP025096_2	2.23\|2329260\|35\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2329260-2329294	35	MN693765	Marine virus AFVG_250M576, complete genome	33065-33099	10	0.714
NZ_CP025096_6	6.16\|7326699\|35\|NZ_CP025096\|CRISPRCasFinder	7326699-7326733	35	HQ317391	Cyanophage S-SSM6a genomic sequence	83051-83085	10	0.714
NZ_CP025096_6	6.16\|7326699\|35\|NZ_CP025096\|CRISPRCasFinder	7326699-7326733	35	GU071098	Synechococcus phage S-SSM7, complete genome	194901-194935	10	0.714
NZ_CP025096_6	6.124\|7326700\|35\|NZ_CP025096\|PILER-CR	7326700-7326734	35	HQ317391	Cyanophage S-SSM6a genomic sequence	83051-83085	10	0.714
NZ_CP025096_6	6.124\|7326700\|35\|NZ_CP025096\|PILER-CR	7326700-7326734	35	GU071098	Synechococcus phage S-SSM7, complete genome	194901-194935	10	0.714
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1070559-1070594	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	976326-976361	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1039527-1039562	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	975423-975458	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	976318-976353	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	975674-975709	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	976309-976344	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1070657-1070692	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1070652-1070687	10	0.722
NZ_CP025096_10	10.4\|8412843\|36\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	8412843-8412878	36	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1070636-1070671	10	0.722
NZ_CP025096_13	13.1\|8657472\|33\|NZ_CP025096\|CRISPRCasFinder	8657472-8657504	33	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	315730-315762	10	0.697
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510993	Pseudomonas phage BR201, partial genome	6019-6055	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510962	Pseudomonas phage CF3, partial genome	17172-17208	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510987	Pseudomonas phage BR233, partial genome	24656-24692	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510984	Pseudomonas phage BR200, partial genome	9288-9324	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510974	Pseudomonas phage CF140, partial genome	24626-24662	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	NC_007805	Pseudomonas phage F10, complete genome	23001-23037	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510978	Pseudomonas phage CF208, partial genome	24766-24802	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510988	Pseudomonas phage BR299, partial genome	24846-24882	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510976	Pseudomonas phage CF165, partial genome	4588-4624	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	KY707339	Pseudomonas phage JBD68, complete genome	24865-24901	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510992	Pseudomonas phage BR144, partial genome	9636-9672	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510975	Pseudomonas phage CF145, partial genome	24942-24978	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	MK510986	Pseudomonas phage BR213, partial genome	24650-24686	11	0.703
NZ_CP025096_2	2.1\|2327830\|37\|NZ_CP025096\|PILER-CR,CRISPRCasFinder,CRT	2327830-2327866	37	DQ163912	Bacteriophage F10, complete genome	23001-23037	11	0.703

1. spacer 3.1|4674607|27|NZ_CP025096|CRISPRCasFinder matches to NZ_CP033579 (Vibrio mediterranei strain 117-T6 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.778

cttaaaaaagggtagcccgttaaggag	CRISPR spacer
aaaaaaaaaggatagcccgttaaggct	Protospacer
   ********.*************

2. spacer 3.1|4674607|27|NZ_CP025096|CRISPRCasFinder matches to MK249133 (Blackfly microvirus SF02 isolate 017, complete genome) position: , mismatch: 6, identity: 0.778

cttaaaaaagggtagcccgttaaggag	CRISPR spacer
aattaaaaagggtagcccattaagggc	Protospacer
  * **************.******.

3. spacer 6.24|7327224|35|NZ_CP025096|CRISPRCasFinder matches to NZ_CP022220 (Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence) position: , mismatch: 8, identity: 0.771

aaggattggaagggcttgaggaagcgtttaaagaa	CRISPR spacer
aaggattggaagggattgaggaagcttctgacctc	Protospacer
************** ********** *.*.*

4. spacer 6.24|7327224|35|NZ_CP025096|CRISPRCasFinder matches to NZ_CP030052 (Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.771

aaggattggaagggcttgaggaagcgtttaaagaa	CRISPR spacer
aaggattggaagggattgaggaagcttctgacctc	Protospacer
************** ********** *.*.*

5. spacer 6.24|7327224|35|NZ_CP025096|CRISPRCasFinder matches to NZ_CP030054 (Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

aaggattggaagggcttgaggaagcgtttaaagaa	CRISPR spacer
aaggattggaagggattgaggaagcttctgacctc	Protospacer
************** ********** *.*.*

6. spacer 6.132|7327225|35|NZ_CP025096|PILER-CR matches to NZ_CP022220 (Bradyrhizobium guangxiense strain CCBAU 53363 plasmid p53363, complete sequence) position: , mismatch: 8, identity: 0.771

aaggattggaagggcttgaggaagcgtttaaagaa	CRISPR spacer
aaggattggaagggattgaggaagcttctgacctc	Protospacer
************** ********** *.*.*

7. spacer 6.132|7327225|35|NZ_CP025096|PILER-CR matches to NZ_CP030052 (Bradyrhizobium guangdongense strain CCBAU 51649 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.771

aaggattggaagggcttgaggaagcgtttaaagaa	CRISPR spacer
aaggattggaagggattgaggaagcttctgacctc	Protospacer
************** ********** *.*.*

8. spacer 6.132|7327225|35|NZ_CP025096|PILER-CR matches to NZ_CP030054 (Bradyrhizobium guangzhouense strain CCBAU 51670 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

aaggattggaagggcttgaggaagcgtttaaagaa	CRISPR spacer
aaggattggaagggattgaggaagcttctgacctc	Protospacer
************** ********** *.*.*

9. spacer 2.36|2330112|35|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NC_048068 (Microbacterium phage OneinaGillian, complete genome) position: , mismatch: 9, identity: 0.743

gccacgtgctggtcaaagtcgctatcgacaataac	CRISPR spacer
tacacgtgctggtcgaagtcgcaatcgaacttgcc	Protospacer
  ************.******* *****   *. *

10. spacer 6.6|7326042|35|NZ_CP025096|CRISPRCasFinder matches to NZ_CP024036 (Bacillus aryabhattai strain K13 plasmid unnamed1) position: , mismatch: 9, identity: 0.743

acatacaggcttaagttcgctcaatccttttaccc	CRISPR spacer
gaaaccctgtttatgttcgctcaatcgttttaccc	Protospacer
. *  *  *.*** ************ ********

11. spacer 6.17|7326764|35|NZ_CP025096|CRISPRCasFinder matches to NZ_CP042276 (Agrobacterium tumefaciens strain 186 plasmid pAt, complete sequence) position: , mismatch: 9, identity: 0.743

ttggccactccgaacgggttgcccccgt---tgtccga	CRISPR spacer
gccgccactccgatcgggttgccgccgtacgtgcc---	Protospacer
 . ********** ********* ****   **.*

12. spacer 6.114|7326043|35|NZ_CP025096|PILER-CR matches to NZ_CP024036 (Bacillus aryabhattai strain K13 plasmid unnamed1) position: , mismatch: 9, identity: 0.743

acatacaggcttaagttcgctcaatccttttaccc	CRISPR spacer
gaaaccctgtttatgttcgctcaatcgttttaccc	Protospacer
. *  *  *.*** ************ ********

13. spacer 6.125|7326765|35|NZ_CP025096|PILER-CR matches to NZ_CP042276 (Agrobacterium tumefaciens strain 186 plasmid pAt, complete sequence) position: , mismatch: 9, identity: 0.743

ttggccactccgaacgggttgcccccgt---tgtccga	CRISPR spacer
gccgccactccgatcgggttgccgccgtacgtgcc---	Protospacer
 . ********** ********* ****   **.*

14. spacer 10.9|8413171|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK962634 (Achromobacter phage vB_AxyS_19-32_Axy16, complete genome) position: , mismatch: 9, identity: 0.757

ttggcgacgtaatagtcaccatccggcagatacacgg	CRISPR spacer
tcgttcatgtaataggcaccacccggcagatacaggt	Protospacer
*.* . *.******* *****.************ *

15. spacer 10.22|8414023|35|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to JX469828 (Uncultured bacterium plasmid pRSB223, complete sequence) position: , mismatch: 9, identity: 0.743

gaactggtggtgtagtcggtaatggtcggcggtgt	CRISPR spacer
caagggtgggtgtggtcggtgatggtcggcggtca	Protospacer
 **  *  *****.******.************

16. spacer 2.23|2329260|35|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MN693765 (Marine virus AFVG_250M576, complete genome) position: , mismatch: 10, identity: 0.714

gtattttaaaaatgccggaatcaaaaaaggttgtg	CRISPR spacer
ttattttataaatgccgcaatcaaaacacacgcag	Protospacer
 ******* ******** ******** * ..   *

17. spacer 6.16|7326699|35|NZ_CP025096|CRISPRCasFinder matches to HQ317391 (Cyanophage S-SSM6a genomic sequence) position: , mismatch: 10, identity: 0.714

gattcaatccgcagcggattcaggtctgaacttaa	CRISPR spacer
aaagtcttccgcagcagatacaggtctgaactcag	Protospacer
.*  .  ********.*** ************.*.

18. spacer 6.16|7326699|35|NZ_CP025096|CRISPRCasFinder matches to GU071098 (Synechococcus phage S-SSM7, complete genome) position: , mismatch: 10, identity: 0.714

gattcaatccgcagcggattcaggtctgaacttaa	CRISPR spacer
aaagtcttccgcagcagatacaggtctgaactcag	Protospacer
.*  .  ********.*** ************.*.

19. spacer 6.124|7326700|35|NZ_CP025096|PILER-CR matches to HQ317391 (Cyanophage S-SSM6a genomic sequence) position: , mismatch: 10, identity: 0.714

gattcaatccgcagcggattcaggtctgaacttaa	CRISPR spacer
aaagtcttccgcagcagatacaggtctgaactcag	Protospacer
.*  .  ********.*** ************.*.

20. spacer 6.124|7326700|35|NZ_CP025096|PILER-CR matches to GU071098 (Synechococcus phage S-SSM7, complete genome) position: , mismatch: 10, identity: 0.714

gattcaatccgcagcggattcaggtctgaacttaa	CRISPR spacer
aaagtcttccgcagcagatacaggtctgaactcag	Protospacer
.*  .  ********.*** ************.*.

21. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

22. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

23. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

24. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

25. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

26. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

27. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

28. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

29. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

30. spacer 10.4|8412843|36|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

ttatcctgcgccacgcctggcacactggccaccagt	CRISPR spacer
ccctcctgcgccacgccgggcaccctggcgccagga	Protospacer
.. ************** ***** *****  * .*

31. spacer 13.1|8657472|33|NZ_CP025096|CRISPRCasFinder matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 10, identity: 0.697

agtgatgcgtgggcgtaatctgcacgacgaacg	CRISPR spacer
caccgcagctgggcgtaatctgctcgacgaacg	Protospacer
 .. ...  ************** *********

32. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510993 (Pseudomonas phage BR201, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

33. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510962 (Pseudomonas phage CF3, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

34. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510987 (Pseudomonas phage BR233, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

35. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510984 (Pseudomonas phage BR200, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

36. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510974 (Pseudomonas phage CF140, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

37. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to NC_007805 (Pseudomonas phage F10, complete genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

38. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510978 (Pseudomonas phage CF208, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

39. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510988 (Pseudomonas phage BR299, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

40. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510976 (Pseudomonas phage CF165, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

41. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to KY707339 (Pseudomonas phage JBD68, complete genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

42. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510992 (Pseudomonas phage BR144, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

43. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510975 (Pseudomonas phage CF145, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

44. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to MK510986 (Pseudomonas phage BR213, partial genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

45. spacer 2.1|2327830|37|NZ_CP025096|PILER-CR,CRISPRCasFinder,CRT matches to DQ163912 (Bacteriophage F10, complete genome) position: , mismatch: 11, identity: 0.703

gtacttgggtcgagttcaccactcagtacaacatccg	CRISPR spacer
atggaggggtcgagttcgccactcagcacaacggctt	Protospacer
.*.   ***********.********.*****. *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4150332 : 4189178

Escherichia_phage(37.5%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100989506.1\|4150332_4151340_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_157815981.1\|4151353_4151728_+	hypothetical protein	A0A0U2RK18	Escherichia_phage	2.2e-19	42.7
WP_100989508.1\|4152178_4152505_+	hypothetical protein	NA	NA	NA	NA
WP_100989509.1\|4152662_4153121_+	response regulator	NA	NA	NA	NA
WP_100989510.1\|4153181_4154162_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_170069503.1\|4154357_4155053_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.0e-21	29.8
WP_100989512.1\|4156832_4157042_-	hypothetical protein	NA	NA	NA	NA
WP_100989513.1\|4157553_4157814_-	hypothetical protein	NA	NA	NA	NA
WP_100989514.1\|4158015_4158219_+	hypothetical protein	NA	NA	NA	NA
WP_100993920.1\|4158578_4159394_-	hypothetical protein	NA	NA	NA	NA
WP_100989515.1\|4161024_4162431_+	serine hydrolase	NA	NA	NA	NA
WP_100989516.1\|4163153_4163558_-	energy transducer TonB	NA	NA	NA	NA
WP_100989517.1\|4163678_4164746_-	AhpC/TSA family protein	NA	NA	NA	NA
WP_100989518.1\|4165143_4165695_-	dihydrofolate reductase family protein	NA	NA	NA	NA
WP_100989519.1\|4165819_4166011_-	hypothetical protein	NA	NA	NA	NA
WP_100989520.1\|4166243_4167227_-	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_100989521.1\|4167410_4168097_-	recombinase family protein	A0A1B1IWV2	uncultured_Mediterranean_phage	2.2e-33	48.0
WP_170069434.1\|4168385_4169273_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_100989522.1\|4169411_4169834_+	response regulator	NA	NA	NA	NA
WP_100989523.1\|4170329_4170464_-	DUF1376 domain-containing protein	NA	NA	NA	NA
WP_100989525.1\|4170658_4170961_-	hypothetical protein	NA	NA	NA	NA
WP_100989526.1\|4171253_4171481_+	hypothetical protein	NA	NA	NA	NA
WP_100989527.1\|4171477_4171885_-\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	5.5e-24	44.9
WP_100989528.1\|4171914_4172211_-	hypothetical protein	A0A0U2RK18	Escherichia_phage	4.9e-14	50.6
WP_100989529.1\|4172339_4172723_-	reactive intermediate/imine deaminase	NA	NA	NA	NA
WP_100989530.1\|4173128_4173551_-	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_100989531.1\|4173813_4174818_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_100989532.1\|4175281_4176823_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	1.2e-82	38.1
WP_100993922.1\|4176871_4177615_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.1e-45	43.5
WP_100989533.1\|4177682_4178888_-	HNH endonuclease	NA	NA	NA	NA
WP_100989534.1\|4179158_4179557_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_100989535.1\|4179556_4179772_-	DUF2281 domain-containing protein	NA	NA	NA	NA
WP_100989536.1\|4184428_4184614_+	hypothetical protein	NA	NA	NA	NA
WP_100989537.1\|4184890_4187488_-	response regulator	A0A1V0SGX0	Hokovirus	1.9e-48	33.9
WP_157815985.1\|4188104_4188284_+\|transposase	transposase	NA	NA	NA	NA
WP_100989539.1\|4188288_4188666_+	hypothetical protein	NA	NA	NA	NA
WP_157815986.1\|4188746_4189178_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

4219189 : 4258522

Acinetobacter_phage(20.0%)

integrase,tRNA,transposase

attL 4248756:4248770|attR 4256339:4256353

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100989571.1\|4219189_4220017_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.9e-18	32.7
WP_100989572.1\|4220006_4220216_+	hypothetical protein	NA	NA	NA	NA
WP_100989574.1\|4220924_4222559_+	PAS domain-containing protein	NA	NA	NA	NA
WP_100989575.1\|4222775_4223477_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_100989576.1\|4224016_4224562_+	hypothetical protein	NA	NA	NA	NA
WP_100989577.1\|4224688_4225792_+	alpha/beta hydrolase	A0A2K9L3Q5	Tupanvirus	7.5e-15	27.3
WP_100989579.1\|4226690_4227323_-	recombinase family protein	A0A0F7L6S1	uncultured_marine_virus	2.5e-23	40.7
WP_100989580.1\|4227329_4227512_-	hypothetical protein	NA	NA	NA	NA
WP_100989581.1\|4227523_4227880_-	hypothetical protein	NA	NA	NA	NA
WP_100989582.1\|4227882_4228074_-	hypothetical protein	NA	NA	NA	NA
WP_100989583.1\|4228404_4228998_+	hypothetical protein	NA	NA	NA	NA
WP_100989584.1\|4229098_4229281_+	hypothetical protein	NA	NA	NA	NA
WP_100989585.1\|4229352_4229574_+	hypothetical protein	NA	NA	NA	NA
WP_157815866.1\|4230314_4230407_+	hypothetical protein	NA	NA	NA	NA
WP_100989586.1\|4230805_4231951_-	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_100989587.1\|4232002_4233061_-	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_100989588.1\|4233233_4237931_-	translocation/assembly module TamB	NA	NA	NA	NA
WP_100989589.1\|4238065_4239064_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.6e-75	44.6
WP_100989590.1\|4239111_4239996_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_100989591.1\|4240021_4240864_+	hypothetical protein	NA	NA	NA	NA
WP_100989592.1\|4240995_4241391_+	VOC family protein	NA	NA	NA	NA
WP_100989593.1\|4241400_4242369_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_100989594.1\|4242620_4245182_-	transglycosylase domain-containing protein	NA	NA	NA	NA
WP_100989595.1\|4245434_4245902_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_100989596.1\|4246257_4247076_-	anti-sigma factor	NA	NA	NA	NA
WP_100993925.1\|4247072_4247627_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_100989597.1\|4247770_4248763_-	fasciclin domain-containing protein	NA	NA	NA	NA
4248756:4248770	attL	NA	NA	NA	NA
WP_100989598.1\|4248902_4250447_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_100989599.1\|4250572_4250815_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_100989600.1\|4250882_4251455_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_100989601.1\|4251554_4252742_+\|integrase	site-specific integrase	S5W9T9	Leptospira_phage	4.9e-36	34.3
WP_100993926.1\|4252716_4252974_-	hypothetical protein	NA	NA	NA	NA
WP_100989602.1\|4253310_4253787_+	hypothetical protein	NA	NA	NA	NA
WP_100989603.1\|4253969_4254467_+	hypothetical protein	NA	NA	NA	NA
WP_157815991.1\|4254872_4255247_+	RDD family protein	NA	NA	NA	NA
WP_170069435.1\|4255271_4255538_+	hypothetical protein	NA	NA	NA	NA
WP_100989605.1\|4255591_4255870_+	hypothetical protein	NA	NA	NA	NA
WP_100989606.1\|4255944_4256781_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
4256339:4256353	attR	NA	NA	NA	NA
WP_157815993.1\|4256873_4257248_-	hypothetical protein	NA	NA	NA	NA
WP_100989607.1\|4257384_4257753_-\|transposase	transposase	NA	NA	NA	NA
WP_100989608.1\|4257700_4258282_-\|transposase	transposase	NA	NA	NA	NA
WP_100989609.1\|4258282_4258522_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

6055222 : 6067909

Vibrio_phage(33.33%)

tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100991149.1\|6055222_6056233_-\|tail	tail fiber domain-containing protein	A0A2I7S7V8	Vibrio_phage	2.1e-08	32.1
WP_100991151.1\|6056263_6059533_-\|plate	baseplate J/gp47 family protein	NA	NA	NA	NA
WP_100991153.1\|6059596_6060007_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_100991155.1\|6060175_6060466_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_100991157.1\|6060475_6062224_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_100991159.1\|6062230_6063019_-	hypothetical protein	NA	NA	NA	NA
WP_170069450.1\|6063042_6063219_-	hypothetical protein	NA	NA	NA	NA
WP_100991161.1\|6063231_6063741_-\|tail	phage tail protein	NA	NA	NA	NA
WP_100991163.1\|6063744_6064179_-\|tail	phage tail protein	A0A059XP41	uncultured_phage	2.0e-24	46.7
WP_100994047.1\|6064306_6065809_-\|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.4e-27	40.7
WP_100991165.1\|6066493_6067909_-\|tail	phage tail sheath family protein	NA	NA	NA	NA

DBSCAN-SWA_4

7494900 : 7622954

117

Escherichia_phage(25.0%)

protease,integrase,transposase

attL 7498722:7498738|attR 7542697:7542713

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100992540.1\|7494900_7495647_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_100992541.1\|7496056_7496962_-	DUF3667 domain-containing protein	NA	NA	NA	NA
WP_170069467.1\|7497262_7498198_-	hypothetical protein	NA	NA	NA	NA
WP_100992543.1\|7498262_7500653_-	ABC transporter permease	NA	NA	NA	NA
7498722:7498738	attL	NA	NA	NA	NA
WP_100992544.1\|7501209_7501536_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_100992545.1\|7501539_7504194_+	ABC transporter permease	NA	NA	NA	NA
WP_100992546.1\|7504550_7505849_+	hypothetical protein	NA	NA	NA	NA
WP_157816101.1\|7506059_7506608_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_100992548.1\|7507232_7508378_-	histidine kinase	Q9EYF3	Enterobacteria_phage	4.4e-18	32.1
WP_100992549.1\|7508559_7510947_+	TonB-dependent receptor	NA	NA	NA	NA
WP_100992550.1\|7510961_7511750_-	response regulator transcription factor	NA	NA	NA	NA
WP_100992551.1\|7512180_7512633_-	cupin domain-containing protein	NA	NA	NA	NA
WP_100994142.1\|7512875_7513118_+	hypothetical protein	NA	NA	NA	NA
WP_100992552.1\|7513164_7513428_+	hypothetical protein	A0A0U2RK18	Escherichia_phage	5.7e-14	49.4
WP_100992553.1\|7513523_7513898_+	hypothetical protein	A0A0U2RK18	Escherichia_phage	1.7e-19	41.2
WP_100992554.1\|7513970_7515542_-	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	5.2e-86	36.6
WP_100992555.1\|7516588_7516930_+	hypothetical protein	NA	NA	NA	NA
WP_157816102.1\|7517328_7518654_+	hypothetical protein	NA	NA	NA	NA
WP_100992557.1\|7518666_7519086_+	hypothetical protein	NA	NA	NA	NA
WP_100992558.1\|7519184_7520723_+	hypothetical protein	NA	NA	NA	NA
WP_100992559.1\|7520725_7524256_+	hypothetical protein	NA	NA	NA	NA
WP_100992560.1\|7524267_7525491_+	hypothetical protein	NA	NA	NA	NA
WP_100992561.1\|7525519_7527247_+	hypothetical protein	NA	NA	NA	NA
WP_100992562.1\|7527268_7529140_+	hypothetical protein	NA	NA	NA	NA
WP_100992563.1\|7529141_7529744_+	OmpA family protein	NA	NA	NA	NA
WP_100992564.1\|7529946_7530201_-	hypothetical protein	A0A0U2RK18	Escherichia_phage	3.5e-08	43.3
WP_100992565.1\|7531999_7532191_-	hypothetical protein	NA	NA	NA	NA
WP_100992566.1\|7533399_7534527_+	replication initiation protein	NA	NA	NA	NA
WP_100992567.1\|7534690_7535179_+	hypothetical protein	NA	NA	NA	NA
WP_157816103.1\|7535250_7535508_+	hypothetical protein	NA	NA	NA	NA
WP_100992569.1\|7536068_7536260_-	hypothetical protein	NA	NA	NA	NA
WP_100992570.1\|7536372_7536990_+	hypothetical protein	NA	NA	NA	NA
WP_143100761.1\|7537001_7537196_+	hypothetical protein	NA	NA	NA	NA
WP_100992572.1\|7537228_7538905_+	hypothetical protein	NA	NA	NA	NA
WP_100992573.1\|7538948_7539275_+	hypothetical protein	NA	NA	NA	NA
WP_100992574.1\|7539374_7540163_+	hypothetical protein	NA	NA	NA	NA
WP_100992575.1\|7540253_7540787_+	hypothetical protein	NA	NA	NA	NA
WP_100992576.1\|7540987_7541965_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_100992577.1\|7542023_7542221_-	hypothetical protein	NA	NA	NA	NA
WP_157816104.1\|7542638_7543283_-	hypothetical protein	NA	NA	NA	NA
7542697:7542713	attR	NA	NA	NA	NA
WP_100992579.1\|7543461_7543962_-	hypothetical protein	NA	NA	NA	NA
WP_157816105.1\|7544028_7544418_-	hypothetical protein	NA	NA	NA	NA
WP_100992581.1\|7544719_7545877_+	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	9.3e-16	26.3
WP_100992582.1\|7545949_7546270_+	hypothetical protein	NA	NA	NA	NA
WP_100992583.1\|7546460_7548002_-	serine hydrolase	NA	NA	NA	NA
WP_100992584.1\|7548084_7550571_-	TonB-dependent receptor	NA	NA	NA	NA
WP_157816106.1\|7550858_7551878_+	histidine kinase	NA	NA	NA	NA
WP_100992586.1\|7551882_7552650_+	response regulator transcription factor	NA	NA	NA	NA
WP_157627111.1\|7553034_7553175_+	hypothetical protein	NA	NA	NA	NA
WP_100992587.1\|7553255_7556372_+	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	1.5e-15	21.6
WP_100992588.1\|7556662_7557136_+	hypothetical protein	NA	NA	NA	NA
WP_100992589.1\|7559197_7560289_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_100992590.1\|7560878_7561112_-\|transposase	transposase	U5P429	Shigella_phage	2.4e-08	40.9
WP_100992591.1\|7562015_7562294_+	hypothetical protein	NA	NA	NA	NA
WP_100992592.1\|7562259_7562604_+\|transposase	transposase	NA	NA	NA	NA
WP_100994143.1\|7562807_7564331_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.3e-45	32.5
WP_157816107.1\|7564922_7565279_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_100992594.1\|7565341_7565641_-\|transposase	transposase	NA	NA	NA	NA
WP_100992595.1\|7565883_7566696_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_100992596.1\|7566886_7567366_-	DUF892 family protein	NA	NA	NA	NA
WP_100992597.1\|7568253_7568697_-	hypothetical protein	NA	NA	NA	NA
WP_100992598.1\|7568799_7569267_+	low affinity iron permease family protein	A0A1C9EHA1	Mycobacterium_phage	1.3e-08	34.0
WP_100994144.1\|7571639_7573121_+	arabinose isomerase	NA	NA	NA	NA
WP_100994145.1\|7573169_7574084_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_100992599.1\|7574351_7577528_+	TonB-dependent receptor	NA	NA	NA	NA
WP_100992600.1\|7577533_7579027_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_100994146.1\|7579183_7580770_+	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_100992601.1\|7580990_7581839_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_100992602.1\|7581924_7582215_+	hypothetical protein	NA	NA	NA	NA
WP_100992603.1\|7582390_7582927_+	hypothetical protein	NA	NA	NA	NA
WP_100992604.1\|7583067_7583808_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_100992605.1\|7583935_7584226_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_100992606.1\|7584285_7584879_+	hypothetical protein	NA	NA	NA	NA
WP_100992607.1\|7584932_7585262_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_100992608.1\|7585245_7585668_+	EVE domain-containing protein	NA	NA	NA	NA
WP_100992609.1\|7585767_7586199_+	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_100992610.1\|7586425_7587280_+	SDR family NAD(P)-dependent oxidoreductase	A0A0M4JSW6	Mollivirus	1.4e-05	38.0
WP_100992612.1\|7588743_7589148_-	VOC family protein	NA	NA	NA	NA
WP_100992613.1\|7589234_7589936_-	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	7.6e-29	36.2
WP_100992614.1\|7590175_7590826_-	hypothetical protein	NA	NA	NA	NA
WP_100992615.1\|7591204_7591732_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_100992616.1\|7591780_7592614_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_100992617.1\|7592688_7593090_+	ester cyclase	NA	NA	NA	NA
WP_100992618.1\|7595481_7595904_-	BLUF domain-containing protein	NA	NA	NA	NA
WP_100992619.1\|7595958_7596219_-	hypothetical protein	NA	NA	NA	NA
WP_100992620.1\|7596473_7596839_-	response regulator	NA	NA	NA	NA
WP_100992621.1\|7597494_7597812_-	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_100992622.1\|7598550_7599288_+	hypothetical protein	NA	NA	NA	NA
WP_100992623.1\|7599823_7600345_-	hypothetical protein	NA	NA	NA	NA
WP_100992624.1\|7600407_7600986_-	hypothetical protein	NA	NA	NA	NA
WP_100992625.1\|7601377_7601944_+	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_100994147.1\|7603077_7603371_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_100992626.1\|7604016_7604436_+\|transposase	transposase	NA	NA	NA	NA
WP_100992627.1\|7604467_7605040_+\|transposase	transposase	NA	NA	NA	NA
WP_157816108.1\|7605068_7605185_+	hypothetical protein	NA	NA	NA	NA
WP_157816109.1\|7605156_7605339_+\|transposase	transposase	NA	NA	NA	NA
WP_157816110.1\|7605367_7605871_+	hypothetical protein	NA	NA	NA	NA
WP_157816241.1\|7606062_7606422_+\|transposase	transposase	NA	NA	NA	NA
WP_100992628.1\|7606746_7607784_+	aldehyde reductase	NA	NA	NA	NA
WP_157816111.1\|7607867_7608275_+	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_100992630.1\|7608290_7609091_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_100992631.1\|7609217_7610060_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_100992632.1\|7610196_7611078_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_100992634.1\|7611474_7612347_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_100992635.1\|7612445_7613378_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_100992636.1\|7613551_7614142_+	HD domain-containing protein	NA	NA	NA	NA
WP_100992637.1\|7614802_7615231_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_100992638.1\|7616063_7616294_+	hypothetical protein	NA	NA	NA	NA
WP_100992639.1\|7616383_7617187_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_157816112.1\|7617520_7617676_-	hypothetical protein	NA	NA	NA	NA
WP_100992640.1\|7617704_7618460_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_100992641.1\|7619039_7619399_+	VOC family protein	NA	NA	NA	NA
WP_100992642.1\|7619436_7620327_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_100992643.1\|7620598_7621066_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_100992644.1\|7621293_7621560_+	hypothetical protein	NA	NA	NA	NA
WP_157816113.1\|7621624_7622593_-	hypothetical protein	NA	NA	NA	NA
WP_100992646.1\|7622726_7622954_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

7670969 : 7708531

Leptospira_phage(66.67%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157816242.1\|7670969_7671716_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_100992692.1\|7671708_7671999_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_100992693.1\|7672170_7672755_+	hypothetical protein	NA	NA	NA	NA
WP_100992694.1\|7673073_7673850_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_100992695.1\|7675097_7675616_+	heme-degrading domain-containing protein	NA	NA	NA	NA
WP_100992696.1\|7675922_7676336_+	hypothetical protein	NA	NA	NA	NA
WP_100992697.1\|7676357_7676864_+\|transposase	transposase	NA	NA	NA	NA
WP_100994148.1\|7677144_7678449_-	DUF4434 domain-containing protein	NA	NA	NA	NA
WP_100992698.1\|7678644_7679016_-	DoxX family protein	NA	NA	NA	NA
WP_100992699.1\|7679207_7679996_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_100992700.1\|7680011_7680437_-	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_100992701.1\|7680433_7681471_-	aldehyde reductase	NA	NA	NA	NA
WP_100992702.1\|7682065_7683127_+	histidine kinase	NA	NA	NA	NA
WP_100992703.1\|7683139_7684636_+	redoxin family protein	NA	NA	NA	NA
WP_100992704.1\|7684632_7685355_+	response regulator transcription factor	NA	NA	NA	NA
WP_100992705.1\|7685709_7686294_+	hypothetical protein	NA	NA	NA	NA
WP_100992706.1\|7686543_7687329_+	DUF4239 domain-containing protein	NA	NA	NA	NA
WP_100992707.1\|7687777_7689541_+\|tRNA	arginine--tRNA ligase	A0A2K9L2F0	Tupanvirus	8.2e-56	27.6
WP_100992708.1\|7689655_7690624_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_100994149.1\|7690721_7691885_+	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_157816122.1\|7692102_7692774_-	YdcF family protein	NA	NA	NA	NA
WP_100994150.1\|7693047_7693980_-	nucleoside hydrolase	NA	NA	NA	NA
WP_100992710.1\|7694063_7694726_+	NUDIX hydrolase	NA	NA	NA	NA
WP_100992711.1\|7694832_7695465_-	HD domain-containing protein	NA	NA	NA	NA
WP_100992712.1\|7695544_7696822_-	putative sulfate exporter family transporter	NA	NA	NA	NA
WP_100992713.1\|7696844_7697252_-	hypothetical protein	NA	NA	NA	NA
WP_100992715.1\|7699116_7699545_+	response regulator	NA	NA	NA	NA
WP_100992716.1\|7699844_7700696_+	PAS domain-containing protein	NA	NA	NA	NA
WP_100992717.1\|7700711_7701746_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_157816123.1\|7702015_7702237_-	hypothetical protein	NA	NA	NA	NA
WP_100992719.1\|7703304_7704300_+	hypothetical protein	NA	NA	NA	NA
WP_157816124.1\|7704734_7705136_-\|transposase	transposase	S5WIU1	Leptospira_phage	2.0e-26	42.3
WP_170069468.1\|7705077_7705467_-\|transposase	transposase	S5WIU1	Leptospira_phage	6.5e-14	50.0
WP_100992722.1\|7707042_7707306_-\|transposase	transposase	NA	NA	NA	NA
WP_100994151.1\|7707842_7708085_+	hypothetical protein	NA	NA	NA	NA
WP_100986298.1\|7708243_7708531_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

7851218 : 7906675

Acinetobacter_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100992819.1\|7851218_7851896_-\|transposase	transposase	NA	NA	NA	NA
WP_157816128.1\|7851867_7852680_-\|transposase	transposase	NA	NA	NA	NA
WP_100992821.1\|7852907_7854176_+	MFS transporter	NA	NA	NA	NA
WP_100992822.1\|7854390_7855887_+	L-fucose/L-arabinose isomerase family protein	NA	NA	NA	NA
WP_100992823.1\|7855923_7859121_+	TonB-dependent receptor	NA	NA	NA	NA
WP_100994157.1\|7859153_7860590_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_100992824.1\|7860609_7861269_+	hypothetical protein	NA	NA	NA	NA
WP_100992825.1\|7863897_7864605_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_100992826.1\|7864618_7865419_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_100992827.1\|7866039_7867203_-	AI-2E family transporter	NA	NA	NA	NA
WP_100992828.1\|7868445_7868682_+	YtxH domain-containing protein	NA	NA	NA	NA
WP_100994158.1\|7868795_7869224_+	YsnF/AvaK domain-containing protein	NA	NA	NA	NA
WP_100992829.1\|7869260_7870166_+	YsnF/AvaK domain-containing protein	NA	NA	NA	NA
WP_100994159.1\|7870343_7871291_+	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_157816129.1\|7871449_7871824_+	hypothetical protein	NA	NA	NA	NA
WP_157816130.1\|7873088_7873250_+	hypothetical protein	NA	NA	NA	NA
WP_157816131.1\|7873586_7873856_+	hypothetical protein	NA	NA	NA	NA
WP_100992832.1\|7874352_7874799_+	hypothetical protein	NA	NA	NA	NA
WP_100992833.1\|7875693_7876335_-	hypothetical protein	NA	NA	NA	NA
WP_100992834.1\|7876726_7878364_+	AAA family ATPase	A0A075DXT4	Acinetobacter_phage	1.9e-30	27.7
WP_100992835.1\|7878384_7878657_+	hypothetical protein	NA	NA	NA	NA
WP_100992836.1\|7878871_7879684_+	ParA family protein	B0ZSI1	Halomonas_phage	2.2e-11	25.9
WP_100992837.1\|7879697_7880768_+	hypothetical protein	NA	NA	NA	NA
WP_100992838.1\|7881037_7881748_+	hypothetical protein	NA	NA	NA	NA
WP_018622869.1\|7881801_7882044_+	hypothetical protein	NA	NA	NA	NA
WP_100992840.1\|7883066_7883351_+	hypothetical protein	NA	NA	NA	NA
WP_100992841.1\|7883760_7884015_+	hypothetical protein	NA	NA	NA	NA
WP_100992842.1\|7884016_7884265_+	hypothetical protein	NA	NA	NA	NA
WP_157816132.1\|7885573_7886293_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_100992844.1\|7886541_7887027_+	hypothetical protein	NA	NA	NA	NA
WP_100992845.1\|7887140_7887464_+	hypothetical protein	NA	NA	NA	NA
WP_018622878.1\|7887656_7887878_+	hypothetical protein	Q8LT81	Vibrio_virus	3.1e-05	37.9
WP_100992846.1\|7887927_7888533_+	PRTRC system protein E	NA	NA	NA	NA
WP_018622880.1\|7888544_7888763_+	PRTRC system protein C	NA	NA	NA	NA
WP_100992847.1\|7888820_7889942_+	hypothetical protein	NA	NA	NA	NA
WP_100992848.1\|7889925_7890639_+	PRTRC system protein B	NA	NA	NA	NA
WP_018622883.1\|7890640_7891453_+	PRTRC system ThiF family protein	NA	NA	NA	NA
WP_157816133.1\|7891670_7891850_+	hypothetical protein	NA	NA	NA	NA
WP_157816134.1\|7891884_7892304_+	hypothetical protein	NA	NA	NA	NA
WP_100992850.1\|7892514_7892907_+	hypothetical protein	NA	NA	NA	NA
WP_100992851.1\|7893076_7893721_+	hypothetical protein	NA	NA	NA	NA
WP_100992852.1\|7893809_7894391_+	hypothetical protein	NA	NA	NA	NA
WP_100992853.1\|7894454_7895216_+\|transposase	transposase	NA	NA	NA	NA
WP_157816135.1\|7895161_7895497_+\|transposase	transposase	NA	NA	NA	NA
WP_100992854.1\|7895713_7896370_+	HAD family hydrolase	NA	NA	NA	NA
WP_100992855.1\|7896376_7896688_-	isochorismate lyase	NA	NA	NA	NA
WP_100994151.1\|7897174_7897417_+	hypothetical protein	NA	NA	NA	NA
WP_100992856.1\|7897413_7897827_+	putative toxin-antitoxin system toxin component, PIN family	NA	NA	NA	NA
WP_100992857.1\|7898397_7899840_+	mannitol dehydrogenase family protein	E5EQS6	Micromonas_sp._RCC1109_virus	2.9e-51	31.1
WP_100992858.1\|7899873_7901196_+	MFS transporter	NA	NA	NA	NA
WP_100992859.1\|7901743_7902013_+	hypothetical protein	NA	NA	NA	NA
WP_100992860.1\|7902072_7902501_+	response regulator	NA	NA	NA	NA
WP_157816136.1\|7902528_7902801_-	hypothetical protein	NA	NA	NA	NA
WP_100992862.1\|7903269_7903722_-	hypothetical protein	NA	NA	NA	NA
WP_100992863.1\|7904349_7904580_-\|transposase	transposase	U5P429	Shigella_phage	5.2e-11	47.1
WP_100994160.1\|7904622_7905276_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_157816137.1\|7906261_7906675_-\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	6.6e-25	49.2

DBSCAN-SWA_7

8435014 : 8561551

114

Shigella_phage(17.65%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100993293.1\|8435014_8435332_+\|transposase	transposase	NA	NA	NA	NA
WP_157816245.1\|8435259_8435985_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.1e-25	38.3
WP_100993295.1\|8437025_8437217_-	hypothetical protein	NA	NA	NA	NA
WP_100993296.1\|8437413_8437605_-	cold shock domain-containing protein	A0A2H4N7Y6	Lake_Baikal_phage	1.9e-11	53.0
WP_100993297.1\|8437874_8439410_+	hypothetical protein	NA	NA	NA	NA
WP_100993298.1\|8439719_8441162_+	amidohydrolase family protein	NA	NA	NA	NA
WP_100993299.1\|8441759_8442164_+	hypothetical protein	NA	NA	NA	NA
WP_100993300.1\|8443842_8444841_-	acyltransferase	NA	NA	NA	NA
WP_157816174.1\|8445188_8445341_+	hypothetical protein	NA	NA	NA	NA
WP_157816175.1\|8445356_8445593_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_100993302.1\|8445987_8447547_-	hypothetical protein	NA	NA	NA	NA
WP_100993303.1\|8447563_8448361_-	hypothetical protein	NA	NA	NA	NA
WP_100993304.1\|8448434_8453030_-	CHAT domain-containing protein	NA	NA	NA	NA
WP_100993305.1\|8454107_8455772_+	hypothetical protein	NA	NA	NA	NA
WP_157816176.1\|8455967_8456486_+	helix-turn-helix domain-containing protein	K4I413	Acidithiobacillus_phage	2.6e-10	26.6
WP_157816177.1\|8456478_8456646_-	hypothetical protein	NA	NA	NA	NA
WP_100993307.1\|8456927_8457284_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_100993308.1\|8457280_8458165_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_157816178.1\|8458148_8458769_+	hypothetical protein	NA	NA	NA	NA
WP_100993310.1\|8458799_8459774_-	replication initiation protein	NA	NA	NA	NA
WP_100993311.1\|8460355_8460658_+	integration host factor subunit beta	A0A1P8CWT5	Bacillus_phage	1.6e-07	34.1
WP_100993312.1\|8460861_8461176_+	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_100993313.1\|8461798_8462071_+	hypothetical protein	NA	NA	NA	NA
WP_100993314.1\|8462099_8462531_-	response regulator	NA	NA	NA	NA
WP_157816179.1\|8462591_8462861_-	hypothetical protein	NA	NA	NA	NA
WP_100993316.1\|8463171_8463576_+	VOC family protein	NA	NA	NA	NA
WP_100993317.1\|8463847_8464306_+	response regulator	NA	NA	NA	NA
WP_157816180.1\|8464548_8464971_-	BLUF domain-containing protein	NA	NA	NA	NA
WP_100993319.1\|8465032_8465293_-	hypothetical protein	NA	NA	NA	NA
WP_100993320.1\|8465543_8465876_+	hypothetical protein	NA	NA	NA	NA
WP_100993321.1\|8465872_8466193_-	hypothetical protein	NA	NA	NA	NA
WP_100993322.1\|8466361_8466718_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_100993323.1\|8466714_8467608_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_157816181.1\|8467591_8468233_+	hypothetical protein	NA	NA	NA	NA
WP_100993325.1\|8468377_8468677_-	BrnT family toxin	NA	NA	NA	NA
WP_100993326.1\|8468669_8469626_-	replication initiation protein	A0A218MNI2	uncultured_virus	1.0e-12	28.0
WP_100993328.1\|8470899_8472015_+	AhpC/TSA family protein	NA	NA	NA	NA
WP_100993329.1\|8472302_8473031_-	hypothetical protein	NA	NA	NA	NA
WP_100993330.1\|8474003_8474333_+	hypothetical protein	NA	NA	NA	NA
WP_100993331.1\|8474329_8474572_-\|transposase	transposase	NA	NA	NA	NA
WP_100993332.1\|8475410_8475617_-	hypothetical protein	NA	NA	NA	NA
WP_100993333.1\|8475671_8476160_+	hypothetical protein	NA	NA	NA	NA
WP_100993334.1\|8476414_8477080_+	recombinase family protein	A0A2I7REZ1	Vibrio_phage	7.2e-21	33.8
WP_100993335.1\|8477298_8478336_-	hypothetical protein	NA	NA	NA	NA
WP_100993336.1\|8480900_8481419_+	damage-inducible protein DinB	NA	NA	NA	NA
WP_100993337.1\|8481497_8482112_+	cytoplasmic protein	NA	NA	NA	NA
WP_100993338.1\|8482172_8483552_-	hypothetical protein	NA	NA	NA	NA
WP_100993339.1\|8483674_8485099_+	hypothetical protein	NA	NA	NA	NA
WP_100993340.1\|8485378_8485780_-	hypothetical protein	NA	NA	NA	NA
WP_100993341.1\|8486165_8487455_-	serine hydrolase	S5Z991	Mycobacterium_phage	6.9e-20	26.8
WP_157816246.1\|8487829_8488750_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.1e-47	39.9
WP_100993343.1\|8488692_8488995_-\|transposase	transposase	NA	NA	NA	NA
WP_100993344.1\|8489009_8489360_+	hypothetical protein	NA	NA	NA	NA
WP_170069483.1\|8489520_8490927_-	DUF4932 domain-containing protein	NA	NA	NA	NA
WP_100993346.1\|8491685_8491892_+\|transposase	transposase	NA	NA	NA	NA
WP_100993347.1\|8491892_8492117_-\|transposase	transposase	NA	NA	NA	NA
WP_100993350.1\|8492662_8492977_-	hypothetical protein	NA	NA	NA	NA
WP_157816182.1\|8493858_8494248_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_157816183.1\|8494496_8494922_-	response regulator	NA	NA	NA	NA
WP_100993353.1\|8495126_8495510_+	response regulator	NA	NA	NA	NA
WP_100993354.1\|8496095_8496293_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157816184.1\|8496395_8496743_-\|transposase	transposase	NA	NA	NA	NA
WP_100993356.1\|8497014_8497392_-	hypothetical protein	NA	NA	NA	NA
WP_100993358.1\|8498014_8498602_+	hypothetical protein	NA	NA	NA	NA
WP_100993359.1\|8499075_8500179_+	alpha/beta hydrolase	A0A2K9L3Q5	Tupanvirus	3.2e-13	25.6
WP_100993360.1\|8500323_8500893_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_100993361.1\|8501241_8501676_-	hypothetical protein	NA	NA	NA	NA
WP_100993362.1\|8501851_8502247_+	hypothetical protein	NA	NA	NA	NA
WP_100993363.1\|8502547_8503774_-	OmpA family protein	NA	NA	NA	NA
WP_100993364.1\|8503847_8504099_-	hypothetical protein	NA	NA	NA	NA
WP_100993365.1\|8504186_8505059_-	YsnF/AvaK domain-containing protein	NA	NA	NA	NA
WP_100993366.1\|8505127_8505580_-	YsnF/AvaK domain-containing protein	NA	NA	NA	NA
WP_157816185.1\|8505656_8506028_-	hypothetical protein	NA	NA	NA	NA
WP_100993368.1\|8506155_8507196_-	YrzE family protein	NA	NA	NA	NA
WP_100993369.1\|8507467_8507713_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_100993370.1\|8508120_8508444_+	hypothetical protein	NA	NA	NA	NA
WP_100993371.1\|8508660_8509293_-	DUF4468 domain-containing protein	NA	NA	NA	NA
WP_100992402.1\|8509471_8509702_+\|transposase	transposase	U5P429	Shigella_phage	4.0e-11	47.1
WP_100993372.1\|8509820_8510303_+	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_100993373.1\|8510324_8510612_+	hypothetical protein	NA	NA	NA	NA
WP_100993375.1\|8511584_8512142_+	DinB family protein	NA	NA	NA	NA
WP_100993376.1\|8512377_8512722_-	hypothetical protein	NA	NA	NA	NA
WP_100993377.1\|8513948_8514857_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_100993379.1\|8516019_8516496_+	response regulator	NA	NA	NA	NA
WP_100993380.1\|8516588_8517155_-	hypothetical protein	NA	NA	NA	NA
WP_100994180.1\|8517493_8517949_+	response regulator	NA	NA	NA	NA
WP_100993381.1\|8518183_8519287_+	alpha/beta hydrolase	A0A2K9L3Q5	Tupanvirus	3.2e-13	27.2
WP_100993382.1\|8519431_8520022_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_100993383.1\|8520155_8522693_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	2.8e-12	26.2
WP_100993384.1\|8522801_8523515_-	recombinase family protein	A0A0F7L6S1	uncultured_marine_virus	4.2e-27	40.7
WP_100993385.1\|8523715_8524000_-	hypothetical protein	NA	NA	NA	NA
WP_100993386.1\|8524074_8524302_-	hypothetical protein	NA	NA	NA	NA
WP_100993387.1\|8524507_8525974_-	hypothetical protein	NA	NA	NA	NA
WP_100993388.1\|8526951_8527188_-\|transposase	transposase	NA	NA	NA	NA
WP_157816186.1\|8527406_8527925_+	hypothetical protein	NA	NA	NA	NA
WP_100993390.1\|8528173_8528542_+	hypothetical protein	NA	NA	NA	NA
WP_100993391.1\|8528732_8529404_+	DUF4468 domain-containing protein	NA	NA	NA	NA
WP_100994181.1\|8530567_8532460_+	histidine kinase	NA	NA	NA	NA
WP_100994182.1\|8533180_8537101_+	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	3.9e-58	32.1
WP_100993392.1\|8537343_8538201_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_100993393.1\|8538432_8538810_+	hypothetical protein	NA	NA	NA	NA
WP_100994183.1\|8539558_8539957_-	response regulator	Q56AR1	Bacillus_thuringiensis_phage	4.6e-07	31.0
WP_100993394.1\|8540103_8542698_-	PAS domain-containing protein	NA	NA	NA	NA
WP_100990055.1\|8543861_8544128_-\|transposase	transposase	NA	NA	NA	NA
WP_100993395.1\|8546077_8547184_+	FecR family protein	NA	NA	NA	NA
WP_100993396.1\|8547221_8550593_+	TonB-dependent receptor	NA	NA	NA	NA
WP_100993397.1\|8550614_8552072_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_100993398.1\|8552253_8554716_+	glycoside hydrolase family 2 protein	L0N6M2	Herpes_simplex_virus	1.6e-28	30.5
WP_100993399.1\|8554754_8557124_+	family 78 glycoside hydrolase catalytic domain	NA	NA	NA	NA
WP_157816187.1\|8557312_8557822_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_100993401.1\|8558231_8558612_+	hypothetical protein	NA	NA	NA	NA
WP_157816188.1\|8558737_8558905_+	hypothetical protein	NA	NA	NA	NA
WP_100993402.1\|8559095_8559680_+	recombinase family protein	E5FFF9	Burkholderia_phage	6.7e-39	49.2
WP_100993403.1\|8561260_8561551_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_8

8566509 : 8616506

Staphylococcus_phage(20.0%)

protease,integrase,transposase

attL 8602314:8602329|attR 8618529:8618544

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100993406.1\|8566509_8566959_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_157816191.1\|8566969_8567281_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_100993408.1\|8567311_8567626_-	hypothetical protein	NA	NA	NA	NA
WP_100993409.1\|8567624_8568335_+	hypothetical protein	NA	NA	NA	NA
WP_100994185.1\|8569202_8569553_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_100993410.1\|8569795_8570668_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_100993411.1\|8571334_8571649_-	hypothetical protein	NA	NA	NA	NA
WP_100994186.1\|8572328_8575421_+	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	3.5e-33	21.5
WP_100993412.1\|8575585_8575774_+	hypothetical protein	NA	NA	NA	NA
WP_100993413.1\|8575987_8576722_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_100993056.1\|8576900_8577173_-\|transposase	transposase	NA	NA	NA	NA
WP_157816192.1\|8577444_8578224_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_100993415.1\|8578271_8578559_-\|transposase	transposase	NA	NA	NA	NA
WP_100993417.1\|8578848_8579049_+	hypothetical protein	NA	NA	NA	NA
WP_100993418.1\|8579370_8579754_-	YceI family protein	NA	NA	NA	NA
WP_100993419.1\|8579790_8579985_-	hypothetical protein	NA	NA	NA	NA
WP_100993420.1\|8580488_8581484_-	glycosyltransferase	NA	NA	NA	NA
WP_100993421.1\|8582317_8582536_-	glycosyltransferase	NA	NA	NA	NA
WP_100993422.1\|8582636_8584088_-	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_157816193.1\|8584056_8584812_-	O-antigen ligase family protein	NA	NA	NA	NA
WP_100993425.1\|8586075_8586300_-	hypothetical protein	NA	NA	NA	NA
WP_100994187.1\|8586437_8586548_-	hypothetical protein	NA	NA	NA	NA
WP_100993426.1\|8586641_8586845_-	hypothetical protein	NA	NA	NA	NA
WP_100993427.1\|8586847_8587171_-	hypothetical protein	A0A0U2RK18	Escherichia_phage	2.0e-13	49.4
WP_100993428.1\|8587301_8589611_-	polysaccharide biosynthesis tyrosine autokinase	NA	NA	NA	NA
WP_100994188.1\|8590932_8591466_+	hypothetical protein	NA	NA	NA	NA
WP_100993429.1\|8591471_8595017_-	carboxypeptidase-like regulatory domain-containing protein	NA	NA	NA	NA
WP_100993430.1\|8595081_8595381_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_100993431.1\|8595533_8597606_+	glycoside hydrolase family 97 protein	NA	NA	NA	NA
WP_100993432.1\|8597885_8598281_+	GxxExxY protein	A9YW17	Ostreococcus_tauri_virus	6.6e-06	32.3
WP_100993433.1\|8598379_8599351_+	aldo/keto reductase	NA	NA	NA	NA
WP_100993434.1\|8599422_8600106_+	response regulator transcription factor	A0A1J0GWE0	Alteromonas_phage	9.7e-05	22.2
WP_100993435.1\|8600102_8601365_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_100993436.1\|8601427_8603632_+	TonB-dependent receptor	NA	NA	NA	NA
8602314:8602329	attL	NA	NA	NA	NA
WP_100993437.1\|8604739_8606509_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.3e-89	35.8
WP_100993438.1\|8606643_8607468_+\|transposase	transposase	NA	NA	NA	NA
WP_100993439.1\|8607400_8607664_+\|transposase	transposase	NA	NA	NA	NA
WP_157816194.1\|8607792_8608017_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_157816195.1\|8608038_8608557_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_100993441.1\|8609051_8609324_+	hypothetical protein	NA	NA	NA	NA
WP_157816196.1\|8609902_8610184_-	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_100993443.1\|8610843_8611416_-	hypothetical protein	NA	NA	NA	NA
WP_100993444.1\|8611652_8611949_-	hypothetical protein	NA	NA	NA	NA
WP_157816197.1\|8612439_8612658_+	hypothetical protein	NA	NA	NA	NA
WP_100993446.1\|8612805_8613051_-	hypothetical protein	NA	NA	NA	NA
WP_100993447.1\|8613415_8613637_+	hypothetical protein	NA	NA	NA	NA
WP_157816198.1\|8614779_8615289_+	hypothetical protein	NA	NA	NA	NA
WP_100993449.1\|8615418_8615967_+	N-acetyltransferase	NA	NA	NA	NA
WP_100993450.1\|8615997_8616213_+\|transposase	transposase	NA	NA	NA	NA
WP_100990055.1\|8616239_8616506_+\|transposase	transposase	NA	NA	NA	NA
8618529:8618544	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP025096

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection