CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021640	Streptococcus pyogenes strain JS12 chromosome, complete genome	3 crisprs	DinG,csm6,cas9,cas1,cas2,csn2,RT,cas3,DEDDh,csa3	0	2	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021640_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021640_1

785431-785598

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	CRISPRCasFinder

2 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP021640_1

>merge|NZ_CP021640|1|785431-785598|CRISPRCasFinder
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAACTCAAGAGTGAGTCCAGAACCACCAGCGAATGTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAACCACTAGACATCTCAACATCTGGAACGGGATGTTTTAGAGCTATGCTATTTTGAATGGTCTCCATTC

>NZ_CP021640|1|1|785431-785598|CRISPRCasFinder
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	TCAAGAGTGAGTCCAGAACCACCAGCGAAT
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	CACTAGACATCTCAACATCTGGAACGGGAT
GTTTTAGAGCTATGCTATTTTGAATGGTCTCCATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021640.1\|WP_002989934.1\|792233_792725_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_CP021640.1\|WP_002989935.1\|791789_792215_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_CP021640.1\|WP_023080002.1\|775598_776729_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP021640.1\|WP_023080006.1\|774894_775536_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021640.1\|WP_002989953.1\|783468_784338_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP021640.1\|WP_101248367.1\|794510_796160_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_CP021640.1\|WP_002984844.1\|792741_793551_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_CP021640.1\|WP_011106808.1\|773415_774771_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP021640.1\|WP_002989931.1\|793547_794375_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_CP021640.1\|WP_002989951.1\|784334_784676_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP021640.1\|WP_101248360.1\|777490_778255_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP021640.1\|WP_101248366.1\|790563_791583_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_CP021640.1\|WP_014635437.1\|778254_778887_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_CP021640.1\|WP_002984836.1\|796163_796952_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_CP021640.1\|WP_002989943.1\|786241_788074_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP021640.1\|WP_101248365.1\|788260_789811_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
NZ_CP021640.1\|WP_101248362.1\|784665_785328_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP021640.1\|WP_023611147.1\|789996_790434_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP021640.1\|WP_038431305.1\|776738_777491_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_CP021640.1\|WP_101248361.1\|779365_783469_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044

Protein	Function_ID	Function_description	E-value
NZ_CP021640.1\|WP_002989934.1\|792233_792725_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	8.80769e-55
NZ_CP021640.1\|WP_002989935.1\|791789_792215_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	3.64459e-31
NZ_CP021640.1\|WP_023080002.1\|775598_776729_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP021640.1\|WP_002989953.1\|783468_784338_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.48912e-131
NZ_CP021640.1\|WP_101248367.1\|794510_796160_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	9.83896e-77
NZ_CP021640.1\|WP_002984844.1\|792741_793551_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76
NZ_CP021640.1\|WP_011106808.1\|773415_774771_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP021640.1\|WP_002989931.1\|793547_794375_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_CP021640.1\|WP_002989951.1\|784334_784676_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.79e-58
NZ_CP021640.1\|WP_101248360.1\|777490_778255_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.34211e-127
NZ_CP021640.1\|WP_101248366.1\|790563_791583_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	2.98698e-104
NZ_CP021640.1\|WP_014635437.1\|778254_778887_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.90272e-87
NZ_CP021640.1\|WP_002984836.1\|796163_796952_+\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	5.79862e-82
NZ_CP021640.1\|WP_002989943.1\|786241_788074_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP021640.1\|WP_101248365.1\|788260_789811_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	5.33177e-12
NZ_CP021640.1\|WP_101248362.1\|784665_785328_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.70435e-122
NZ_CP021640.1\|WP_023611147.1\|789996_790434_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.28024e-84
NZ_CP021640.1\|WP_038431305.1\|776738_777491_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	1.00613e-107
NZ_CP021640.1\|WP_101248361.1\|779365_783469_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0

>NZ_CP021640.1|WP_101248362.1|784665_785328_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYGEDSELKFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKNMV
>NZ_CP021640.1|WP_002989951.1|784334_784676_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>NZ_CP021640.1|WP_002989953.1|783468_784338_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVKSQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTLFGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKALNNEGKGVPEFRI
>NZ_CP021640.1|WP_101248361.1|779365_783469_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSKSRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDATLLSDILRVNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGVSQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDSYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLINDDSLTFKEAIQKAQVSGQGHSLHEQIANLAGSPAIKKGILQTVKIVDELVKVMGHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAKNIIHLFTLTNLGAPAAFKYFDTTIERNRYKSIKEVLDATLIHQSITGLYETRIDLSQLGGD
>NZ_CP021640.1|WP_014635437.1|778254_778887_+|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHKVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>NZ_CP021640.1|WP_101248360.1|777490_778255_+|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNTLLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_CP021640.1|WP_038431305.1|776738_777491_+|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGCLLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLNSYHQITSDGQLNAQAMIEWRAIKQTESEID
>NZ_CP021640.1|WP_023080002.1|775598_776729_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFYSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTITNLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_CP021640.1|WP_023080006.1|774894_775536_+|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_CP021640.1|WP_011106808.1|773415_774771_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>NZ_CP021640.1|WP_002989943.1|786241_788074_+|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
>NZ_CP021640.1|WP_101248365.1|788260_789811_+|LPXTG-cell-wall-anchor-domain-containing-protein
MNKTKQNKTKQNKTKQNKTKHSLLCRYGLTSAAALLLTFGGASAVRADNESIADTQRKLSELRSRFPKVDDKFKDNNLWDNSPIYQHLKSLEDSLDKYLSELDKNLHHLKGDKGEPGLAGPRGPEGLPGKDGKPGETGPAGPMGPRGEQGAPGAQGPRGEAGKDGAKGDRGETGPAGPMGPRGEKGDAGEQGAPGAQGPRGEAGKDGAKGDRGETGPAGPMGPRGEKGDAGEQGAPGAQGPRGEAGKDGAKGDRGETGPAGPMGPRGEKGDAGEQGAPGAQGPRGEAGKDGAKGDRGETGPAGPVGPRGDKGEKGEQGLPGKDGERGPVGPAGKDGQDGKDGIPGKDGKDGQDGKDGLPGKDGKDGQDGKDGLPGKDGKDGQDGKDGLPGKDGKDGQDGKDGLPGKDGKDGQPGKPAPQTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>NZ_CP021640.1|WP_023611147.1|789996_790434_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSDELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRIEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>NZ_CP021640.1|WP_101248366.1|790563_791583_+|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALPAWCLGHLFPIIGAPVFAILLGMLLALFYGHRDKTEEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIVSTIATALLVAYGLQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVSADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_CP021640.1|WP_002989935.1|791789_792215_+|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_CP021640.1|WP_002989934.1|792233_792725_+|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_CP021640.1|WP_002984844.1|792741_793551_+|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>NZ_CP021640.1|WP_002989931.1|793547_794375_+|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_CP021640.1|WP_101248367.1|794510_796160_+|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPNQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTVTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_CP021640.1|WP_002984836.1|796163_796952_+|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC

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Crispr_ID: NZ_CP021640_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021640_2

1654126-1654375

Orphan

Consensus_repeat	Method
CTTGGTGGTCAGCCTCTAATTTTTGGTGCTTCGCTTCTAG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP021640_2

>merge|NZ_CP021640|2|1654126-1654375|CRISPRCasFinder
CTTGGTGGTCAGCCTCTAATTTTTGGTGCTTCGCTTCTAGGGCTTGGTGATCAGCCTCTAATTTTTGGTGCTTCGCTTCTAGGGCTTGGTGATCAGCCTCTAATTTTTGGTGCTTCGCTTCTAGTTCTTTTTTAGCTGCTCGAGAAGCTTCTAAGTCGTTACTTAGACCTTTACGACTAGCTTCTGAAACCTTATTGGCTTCTGTTAGTTTTTGGTTTTCTGCTTCTAATTGTTGTTGTTTTTGTTGTTG

>NZ_CP021640|2|2|1654126-1654375|CRISPRCasFinder
CTTGGTGGTCAGCCTCTAATTTTTGGTGCTTCGCTTCTAG	GGCTTGGTGATCAGCCTCTAATTTTTGGTGCTTCGCTTCTAGGG
CTTGGTGATCAGCCTCTAATTTTTGGTGCTTCGCTTCTAG	TTCTTTTTTAGCTGCTCGAGAAGCTTCTAAGTCGTTACTTAGACCTTTACGACTAGCTTCTGAAACCTTATTGGCTTCTGTTAGTT
TTTGGTTTTCTGCTTCTAATTGTTGTTGTTTTTGTTGTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021640.1\|WP_101248474.1\|1657900_1659502_-\|M-protein-trans-acting-positive-regulator	unknown	unknown	gnl\|CDD\|285470
NZ_CP021640.1\|WP_011529050.1\|1641218_1642196_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP021640.1\|WP_101248473.1\|1656546_1657713_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP021640.1\|WP_101248469.1\|1648545_1649748_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	unknown	unknown	gnl\|CDD\|223021
NZ_CP021640.1\|WP_000715197.1\|1647373_1648294_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NZ_CP021640.1\|WP_003059481.1\|1643025_1643829_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_CP021640.1\|WP_002982520.1\|1642192_1643014_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_CP021640.1\|WP_002993552.1\|1664367_1665585_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|182528
NZ_CP021640.1\|WP_032465277.1\|1660506_1662135_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP021640.1\|WP_101248475.1\|1665597_1666272_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP021640.1\|WP_101248468.1\|1644889_1647361_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NZ_CP021640.1\|WP_023605323.1\|1644520_1644721_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP021640.1\|WP_101248472.1\|1655021_1656323_-\|M-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP021640.1\|WP_010922707.1\|1639477_1641106_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NZ_CP021640.1\|WP_101248470.1\|1649844_1653339_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801
NZ_CP021640.1\|WP_011285226.1\|1666258_1667527_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914
NZ_CP021640.1\|WP_020837818.1\|1662235_1663624_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP021640.1\|WP_002991237.1\|1663620_1664274_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP021640.1\|WP_002982472.1\|1660177_1660429_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021640.1\|WP_002993600.1\|1643812_1644439_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049

Protein	Function_ID	Function_description	E-value
NZ_CP021640.1\|WP_101248474.1\|1657900_1659502_-\|M-protein-trans-acting-positive-regulator	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	7.87852e-53
NZ_CP021640.1\|WP_011529050.1\|1641218_1642196_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.36961e-107
NZ_CP021640.1\|WP_101248473.1\|1656546_1657713_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	7.01284e-18
NZ_CP021640.1\|WP_101248469.1\|1648545_1649748_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	3.02502e-12
NZ_CP021640.1\|WP_000715197.1\|1647373_1648294_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	3.74951e-122
NZ_CP021640.1\|WP_003059481.1\|1643025_1643829_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85753e-80
NZ_CP021640.1\|WP_002982520.1\|1642192_1643014_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.11383e-69
NZ_CP021640.1\|WP_002993552.1\|1664367_1665585_-\|FtsX-like-permease-family-protein	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.49497e-52
NZ_CP021640.1\|WP_032465277.1\|1660506_1662135_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.47679e-58
NZ_CP021640.1\|WP_101248475.1\|1665597_1666272_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	5.17191e-116
NZ_CP021640.1\|WP_101248468.1\|1644889_1647361_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NZ_CP021640.1\|WP_023605323.1\|1644520_1644721_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	6.24723e-06
NZ_CP021640.1\|WP_101248472.1\|1655021_1656323_-\|M-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	6.92086e-11
NZ_CP021640.1\|WP_010922707.1\|1639477_1641106_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP021640.1\|WP_101248470.1\|1649844_1653339_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.90512e-75
NZ_CP021640.1\|WP_011285226.1\|1666258_1667527_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	3.9346e-22
NZ_CP021640.1\|WP_020837818.1\|1662235_1663624_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.41647e-30
NZ_CP021640.1\|WP_002991237.1\|1663620_1664274_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NZ_CP021640.1\|WP_002993600.1\|1643812_1644439_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.07805e-91

>NZ_CP021640.1|WP_101248470.1|1649844_1653339_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVETPQPTAVSEEAPSSKETKTPQTPDDAEETIADDANDLAPQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIIDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENPPKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLAAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSAEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQVPDKKPETKPEQDGSGQAPDKKPEAKPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTKDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED
>NZ_CP021640.1|WP_101248469.1|1648545_1649748_-|LPXTG-anchored-fibronectin-binding-protein-FbpA
MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDSMQPISSTQGNTASAPQKWHHINDKGFIPLGISLEDAKKDFKEEVEESRLSKEQKEFYNQKIDAETDKDKLLLTYHSEYSEDIKKHSASTEPTTQLVEASVQETQASASDSMVTDDSTSVTADSPKESPVAPASSPESEDSSVASSEETSSPETPVAPALSEAPAQPAESEEPSVAAPSEETPTPSTPEEPAAPAPSPESEEPSVAAPSEETPSPETPAAPETPEEPAAPETPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVMGHESGKYLPSTGEKAQPLFIATMTLMSLLGSLLVTKRQKETKK
>NZ_CP021640.1|WP_000715197.1|1647373_1648294_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>NZ_CP021640.1|WP_101248468.1|1644889_1647361_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNPGQGHQPDNGGYHPAPPRPNDASQNRHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSEHSKPSNKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYIMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NZ_CP021640.1|WP_023605323.1|1644520_1644721_-|CsbD-family-protein
MSEEKLKSKIDQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NZ_CP021640.1|WP_002993600.1|1643812_1644439_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIVISHDFDMLEKLCDACYMIEENRTQLFKHT
>NZ_CP021640.1|WP_003059481.1|1643025_1643829_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NZ_CP021640.1|WP_002982520.1|1642192_1643014_+|ABC-transporter-permease
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NZ_CP021640.1|WP_011529050.1|1641218_1642196_+|ABC-transporter-permease
MKRTTIIIIWKIIRCITLIFGVSVLTFVLLKQSPVDPVMASVNYDTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGASFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV
>NZ_CP021640.1|WP_010922707.1|1639477_1641106_+|ABC-transporter-substrate-binding-protein
MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELVVSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFKKWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKKGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK
>NZ_CP021640.1|WP_101248472.1|1655021_1656323_-|M-protein
MVRKDTNRHYSLRKLKTGTASVAVALSVLGAGLAVNQTEVSAKSVTRSTAQDPDKSRQAITEYEVENHKLTQEKNALTNRNQELTDENGELKTANEALRQRGDTLFNQRVKLEKQVQEKEHNNKTLKIENGELKTENGDLTKKLDETRQELANKQQESKENEKTLNELLEKTVKDKIAKEQENKETIGTLKKLLDETVKDKIAKEQKSKQDFGALKQELAKKEEQNKISDASRQGLRRDLNASREAKKQVEKDLANLTAELDKVKEEKQVSDASRQGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGEAANPFFTAAALTVMATAGVAAVVKRKKEN
>NZ_CP021640.1|WP_101248473.1|1656546_1657713_-|YSIRK-type-signal-peptide-containing-protein
MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAESRGYQVPPRVLLPGKEANKVFEERKALEKQARELGDTINHMSQTISEQSRKIAALKSEAELKNQQALEALNNKNEQIAKLTNENAQLKEAIEGYVQTIQNASREIAANQQELAAAKSQLEAKNAEIEALKQQDASKTEEIAKLQSEAATLENLLGSAKRELTDLQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQAKLDAANAEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEELAKLKADKASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEETTNPFFTAAALTVIASAGVLALKRKEEN
>NZ_CP021640.1|WP_101248474.1|1657900_1659502_-|M-protein-trans-acting-positive-regulator
MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISMLTLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFRDFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLKYFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYKGYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLEIGRAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDITANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVGKELINQLTYCFFITWENSFLKVNQKDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIEKQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKPLEAHSSSKSHSDKEVQKPEKPDNSVKQATSS
>NZ_CP021640.1|WP_002982472.1|1660177_1660429_-|hypothetical-protein
MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NZ_CP021640.1|WP_032465277.1|1660506_1662135_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDESETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPNKDKNDTNQPESSDQSTPSPKDQSSQKESQNKDGRSTPSPDQQKDQTPDKTPEKSADKTPEKGPEKAAEKTPEPNRDAPKPIQPPLAAAAPVFIPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKVTSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>NZ_CP021640.1|WP_020837818.1|1662235_1663624_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLHDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLMFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYERASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NZ_CP021640.1|WP_002991237.1|1663620_1664274_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NZ_CP021640.1|WP_002993552.1|1664367_1665585_-|FtsX-like-permease-family-protein
MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE
>NZ_CP021640.1|WP_101248475.1|1665597_1666272_-|ABC-transporter-ATP-binding-protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEHSYIE
>NZ_CP021640.1|WP_011285226.1|1666258_1667527_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQDKIAQPLPGMKDGMEVGSIVKP

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Crispr_ID: NZ_CP021640_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021640_3

1655713-1655812

Orphan

Consensus_repeat	Method
TTCGCAATTTTATCTTTTACTGTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021640_3

>merge|NZ_CP021640|3|1655713-1655812|CRISPRCasFinder
TTCGCAATTTTATCTTTTACTGTCTCATCCAAGAGTTTTTTAAGGGTGCCAATGGTTTCTTTATTTTCTTGCTCCTTAGCAATTTTATCTTTTACTGTCT

>NZ_CP021640|3|3|1655713-1655812|CRISPRCasFinder
TTCGCAATTTTATCTTTTACTGTCT	CATCCAAGAGTTTTTTAAGGGTGCCAATGGTTTCTTTATTTTCTTGCTCC
TTAGCAATTTTATCTTTTACTGTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021640.1\|WP_101248474.1\|1657900_1659502_-\|M-protein-trans-acting-positive-regulator	unknown	unknown	gnl\|CDD\|285470
NZ_CP021640.1\|WP_011529050.1\|1641218_1642196_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP021640.1\|WP_002982442.1\|1667950_1668235_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021640.1\|WP_101248473.1\|1656546_1657713_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP021640.1\|WP_101248469.1\|1648545_1649748_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	unknown	unknown	gnl\|CDD\|223021
NZ_CP021640.1\|WP_000715197.1\|1647373_1648294_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NZ_CP021640.1\|WP_003059481.1\|1643025_1643829_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_CP021640.1\|WP_002982520.1\|1642192_1643014_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_CP021640.1\|WP_002993552.1\|1664367_1665585_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|182528
NZ_CP021640.1\|WP_032465277.1\|1660506_1662135_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP021640.1\|WP_101248475.1\|1665597_1666272_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP021640.1\|WP_101248468.1\|1644889_1647361_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NZ_CP021640.1\|WP_023605323.1\|1644520_1644721_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP021640.1\|WP_002982472.1\|1660177_1660429_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021640.1\|WP_101248471.1\|1653673_1654813_-\|M-related-protein-Enn	unknown	unknown	gnl\|CDD\|274008
NZ_CP021640.1\|WP_101248470.1\|1649844_1653339_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801
NZ_CP021640.1\|WP_011285226.1\|1666258_1667527_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914
NZ_CP021640.1\|WP_020837818.1\|1662235_1663624_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP021640.1\|WP_002991237.1\|1663620_1664274_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP021640.1\|WP_002993600.1\|1643812_1644439_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049

Protein	Function_ID	Function_description	E-value
NZ_CP021640.1\|WP_101248474.1\|1657900_1659502_-\|M-protein-trans-acting-positive-regulator	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	7.87852e-53
NZ_CP021640.1\|WP_011529050.1\|1641218_1642196_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.36961e-107
NZ_CP021640.1\|WP_101248473.1\|1656546_1657713_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	7.01284e-18
NZ_CP021640.1\|WP_101248469.1\|1648545_1649748_-\|LPXTG-anchored-fibronectin-binding-protein-FbpA	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	3.02502e-12
NZ_CP021640.1\|WP_000715197.1\|1647373_1648294_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	3.74951e-122
NZ_CP021640.1\|WP_003059481.1\|1643025_1643829_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85753e-80
NZ_CP021640.1\|WP_002982520.1\|1642192_1643014_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.11383e-69
NZ_CP021640.1\|WP_002993552.1\|1664367_1665585_-\|FtsX-like-permease-family-protein	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	5.49497e-52
NZ_CP021640.1\|WP_032465277.1\|1660506_1662135_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.47679e-58
NZ_CP021640.1\|WP_101248475.1\|1665597_1666272_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	5.17191e-116
NZ_CP021640.1\|WP_101248468.1\|1644889_1647361_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NZ_CP021640.1\|WP_023605323.1\|1644520_1644721_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	6.24723e-06
NZ_CP021640.1\|WP_101248471.1\|1653673_1654813_-\|M-related-protein-Enn	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	5.24857e-13
NZ_CP021640.1\|WP_101248470.1\|1649844_1653339_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.90512e-75
NZ_CP021640.1\|WP_011285226.1\|1666258_1667527_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	3.9346e-22
NZ_CP021640.1\|WP_020837818.1\|1662235_1663624_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.41647e-30
NZ_CP021640.1\|WP_002991237.1\|1663620_1664274_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NZ_CP021640.1\|WP_002993600.1\|1643812_1644439_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.07805e-91

>NZ_CP021640.1|WP_101248471.1|1653673_1654813_-|M-related-protein-Enn
MTRQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVKADNNNSVSVKNEKNEAKLEAKLYELYDEITNLEEERGKHLDRIEELEAKEKSSEDVERHYLRELDKEYKEHQKEKQQQQQEQEERQKNQEQLERKYQREVEKRYQEQQQKQQQLEAENQKLTEANKVSEASRKGLSNDLEASRAAKKELEAKHQKLEADHQALEAKHQKLEADHQALEAKHQKLEADHQVSEASRKGLNRDLEASREANKKVTSELTQAKAQLSALEESKKLSEKEKAELQAKLDAQGKALKEQLAKQAEELAKLRAEKAAGSKTPATKPANKERSGRAAQTATRPIQNKGMRSQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN
>NZ_CP021640.1|WP_101248470.1|1649844_1653339_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVETPQPTAVSEEAPSSKETKTPQTPDDAEETIADDANDLAPQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIIDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKENPPKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLAAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSAEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQVPDKKPETKPEQDGSGQAPDKKPEAKPEQDGSGQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTKDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED
>NZ_CP021640.1|WP_101248469.1|1648545_1649748_-|LPXTG-anchored-fibronectin-binding-protein-FbpA
MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDSMQPISSTQGNTASAPQKWHHINDKGFIPLGISLEDAKKDFKEEVEESRLSKEQKEFYNQKIDAETDKDKLLLTYHSEYSEDIKKHSASTEPTTQLVEASVQETQASASDSMVTDDSTSVTADSPKESPVAPASSPESEDSSVASSEETSSPETPVAPALSEAPAQPAESEEPSVAAPSEETPTPSTPEEPAAPAPSPESEEPSVAAPSEETPSPETPAAPETPEEPAAPETPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVMGHESGKYLPSTGEKAQPLFIATMTLMSLLGSLLVTKRQKETKK
>NZ_CP021640.1|WP_000715197.1|1647373_1648294_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>NZ_CP021640.1|WP_101248468.1|1644889_1647361_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNPGQGHQPDNGGYHPAPPRPNDASQNRHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSEHSKPSNKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYIMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NZ_CP021640.1|WP_023605323.1|1644520_1644721_-|CsbD-family-protein
MSEEKLKSKIDQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NZ_CP021640.1|WP_002993600.1|1643812_1644439_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIVISHDFDMLEKLCDACYMIEENRTQLFKHT
>NZ_CP021640.1|WP_003059481.1|1643025_1643829_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NZ_CP021640.1|WP_002982520.1|1642192_1643014_+|ABC-transporter-permease
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NZ_CP021640.1|WP_011529050.1|1641218_1642196_+|ABC-transporter-permease
MKRTTIIIIWKIIRCITLIFGVSVLTFVLLKQSPVDPVMASVNYDTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGASFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV
>NZ_CP021640.1|WP_101248473.1|1656546_1657713_-|YSIRK-type-signal-peptide-containing-protein
MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAESRGYQVPPRVLLPGKEANKVFEERKALEKQARELGDTINHMSQTISEQSRKIAALKSEAELKNQQALEALNNKNEQIAKLTNENAQLKEAIEGYVQTIQNASREIAANQQELAAAKSQLEAKNAEIEALKQQDASKTEEIAKLQSEAATLENLLGSAKRELTDLQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQAKLDAANAEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEELAKLKADKASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEETTNPFFTAAALTVIASAGVLALKRKEEN
>NZ_CP021640.1|WP_101248474.1|1657900_1659502_-|M-protein-trans-acting-positive-regulator
MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISMLTLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFRDFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLKYFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYKGYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLEIGRAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDITANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVGKELINQLTYCFFITWENSFLKVNQKDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIEKQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKPLEAHSSSKSHSDKEVQKPEKPDNSVKQATSS
>NZ_CP021640.1|WP_002982472.1|1660177_1660429_-|hypothetical-protein
MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NZ_CP021640.1|WP_032465277.1|1660506_1662135_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDESETPKKDKKSKETASQHDTQKDHKPSHTHPTPPSNDTKQTDQASSEATDKPNKDKNDTNQPESSDQSTPSPKDQSSQKESQNKDGRSTPSPDQQKDQTPDKTPEKSADKTPEKGPEKAAEKTPEPNRDAPKPIQPPLAAAAPVFIPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKVTSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>NZ_CP021640.1|WP_020837818.1|1662235_1663624_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLHDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLMFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYERASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NZ_CP021640.1|WP_002991237.1|1663620_1664274_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NZ_CP021640.1|WP_002993552.1|1664367_1665585_-|FtsX-like-permease-family-protein
MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE
>NZ_CP021640.1|WP_101248475.1|1665597_1666272_-|ABC-transporter-ATP-binding-protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEHSYIE
>NZ_CP021640.1|WP_011285226.1|1666258_1667527_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQDKIAQPLPGMKDGMEVGSIVKP
>NZ_CP021640.1|WP_002982442.1|1667950_1668235_-|hypothetical-protein
MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKDDAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MK448972	Streptococcus phage Javan520, complete genome	12869-12898	0	1.0
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MK448763	Streptococcus phage Javan451, complete genome	13647-13676	0	1.0
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MK448777	Streptococcus phage Javan491, complete genome	13529-13558	0	1.0
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448944	Streptococcus phage Javan452, complete genome	12352-12381	1	0.967
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448672	Streptococcus phage Javan117, complete genome	7933-7962	1	0.967
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448849	Streptococcus phage Javan128, complete genome	7837-7866	1	0.967
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448850	Streptococcus phage Javan132, complete genome	12662-12691	1	0.967
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MK448845	Streptococcus phage Javan118, complete genome	14951-14980	2	0.933
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448675	Streptococcus phage Javan129, complete genome	12142-12171	2	0.933
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448673	Streptococcus phage Javan119, complete genome	11438-11467	2	0.933
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448845	Streptococcus phage Javan118, complete genome	9816-9845	3	0.9
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448771	Streptococcus phage Javan481, complete genome	8088-8117	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448973	Streptococcus phage Javan522, complete genome	9993-10022	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448775	Streptococcus phage Javan489, complete genome	11977-12006	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448969	Streptococcus phage Javan514, complete genome	10959-10988	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448794	Streptococcus phage Javan525, complete genome	10172-10201	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448972	Streptococcus phage Javan520, complete genome	8013-8042	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448763	Streptococcus phage Javan451, complete genome	9206-9235	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448774	Streptococcus phage Javan487, complete genome	8073-8102	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448778	Streptococcus phage Javan493, complete genome	10008-10037	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448773	Streptococcus phage Javan485, complete genome	10959-10988	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448958	Streptococcus phage Javan486, complete genome	10313-10342	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448777	Streptococcus phage Javan491, complete genome	8304-8333	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448765	Streptococcus phage Javan459, complete genome	10172-10201	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK449010	Streptococcus phage Javan90, complete genome	10522-10551	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	MK448833	Streptococcus phage Javan87, complete genome	10522-10551	4	0.867
NZ_CP021640_1	1.2\|785533\|30\|NZ_CP021640\|CRISPRCasFinder	785533-785562	30	NZ_CP010870	Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6001, complete sequence	108515-108544	6	0.8
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	291729-291758	8	0.733
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	JQ692107	Vibrio vulnificus phage SSP002, complete genome	39080-39109	8	0.733
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MN215888	Vibrio phage vB_VpaS_HCMJ, complete genome	39192-39221	8	0.733
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MF754116	Vibrio phage vB_VpaS_KF6, complete genome	37281-37310	8	0.733
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MF754115	Vibrio phage vB_VpaS_KF5, complete genome	39198-39227	8	0.733
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MG602476	Vibrio phage VVP001, complete genome	35844-35873	8	0.733
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	MH925090	UNVERIFIED: Vibrio phage ValLY_3, complete genome	32119-32148	8	0.733
NZ_CP021640_1	1.1\|785467\|30\|NZ_CP021640\|CRISPRCasFinder	785467-785496	30	NZ_LN868946	Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence	116915-116944	10	0.667

1. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagtccagaaccaccagcgaat	Protospacer
******************************

2. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 0, identity: 1.0

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagtccagaaccaccagcgaat	Protospacer
******************************

3. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 0, identity: 1.0

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagtccagaaccaccagcgaat	Protospacer
******************************

4. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

5. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

6. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

7. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

8. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 2, identity: 0.933

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagaccagaaccaccagcaaat	Protospacer
*********** **************.***

9. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 2, identity: 0.933

cactagacatctcaacatctggaacgggat	CRISPR spacer
cactagacatctcaacatctggaacaggtt	Protospacer
*************************.** *

10. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 2, identity: 0.933

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatttcaacatctggaacgggat	Protospacer
*.********.*******************

11. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 3, identity: 0.9

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatttcaacatctggaacgggtt	Protospacer
*.********.***************** *

12. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

13. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

14. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

15. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

16. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

17. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

18. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

19. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

20. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

21. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

22. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

23. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacaggtt	Protospacer
*..**********************.** *

24. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

25. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggtacaggtt	Protospacer
*.******************** **.** *

26. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggtacaggtt	Protospacer
*.******************** **.** *

27. spacer 1.2|785533|30|NZ_CP021640|CRISPRCasFinder matches to NZ_CP010870 (Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6001, complete sequence) position: , mismatch: 6, identity: 0.8

cactaga----catctcaacatctggaacgggat	CRISPR spacer
----agagttccatctcaagatctggcacgggat	Protospacer
    ***    ******** ****** *******

28. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtcattccagaaccaccaaatgcc	Protospacer
******** * *************.  . .

29. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to JQ692107 (Vibrio vulnificus phage SSP002, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

30. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MN215888 (Vibrio phage vB_VpaS_HCMJ, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

31. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MF754116 (Vibrio phage vB_VpaS_KF6, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

32. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MF754115 (Vibrio phage vB_VpaS_KF5, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

33. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MG602476 (Vibrio phage VVP001, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

34. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to MH925090 (UNVERIFIED: Vibrio phage ValLY_3, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

35. spacer 1.1|785467|30|NZ_CP021640|CRISPRCasFinder matches to NZ_LN868946 (Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence) position: , mismatch: 10, identity: 0.667

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gttcagccgaatccagaaccaccagcgaag	Protospacer
 .  .. .**.******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36840 : 49153

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101248257.1\|36840_40566_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.0e-39	27.7
WP_023080049.1\|40726_42181_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.7e-54	32.9
WP_101248258.1\|42208_43231_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FC27	Synechococcus_phage	1.5e-62	42.0
WP_002986700.1\|43398_43953_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_002987711.1\|44136_45684_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	3.4e-45	52.4
WP_101248259.1\|45741_46866_-	CHAP domain-containing protein	F8HGP2	Streptococcus_phage	1.0e-06	28.6
WP_101248260.1\|47118_48384_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002987716.1\|48661_49153_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

323569 : 420498

Streptococcus_phage(20.0%)

transposase,tRNA,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985850.1\|323569_324160_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7
WP_002985847.1\|324651_324927_+	YlbG family protein	NA	NA	NA	NA
WP_010921930.1\|325175_325811_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4
WP_101248292.1\|325828_326704_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.8e-64	44.5
WP_020833285.1\|326722_326962_+	tpl protein	NA	NA	NA	NA
WP_002985838.1\|327366_327690_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_002985836.1\|327694_328558_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
WP_002985833.1\|328584_328977_+	hypothetical protein	NA	NA	NA	NA
WP_011528296.1\|329023_329653_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_101248293.1\|329952_330309_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	3.7e-40	65.8
WP_021340916.1\|330382_331210_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	79.9
WP_012560476.1\|331443_332625_+	L-lactate oxidase	NA	NA	NA	NA
WP_038432823.1\|332890_337834_+\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_002985820.1\|338604_339312_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_162292728.1\|339554_341552_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	5.1e-86	34.9
WP_032460815.1\|342046_343060_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	4.2e-97	53.0
WP_023610055.1\|343063_343552_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_101248295.1\|343518_345699_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.6e-170	43.2
WP_101248296.1\|345860_346613_-	ADP-ribosyltransferase	NA	NA	NA	NA
WP_162292724.1\|347070_347643_+	hypothetical protein	NA	NA	NA	NA
WP_101248298.1\|349531_350020_+	hypothetical protein	NA	NA	NA	NA
WP_011017435.1\|350714_350966_+	hypothetical protein	NA	NA	NA	NA
WP_002990844.1\|352018_352255_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_101248299.1\|352247_352946_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	1.2e-10	25.2
WP_101248300.1\|353021_353981_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002993065.1\|354313_355651_+	MFS transporter	NA	NA	NA	NA
WP_101248301.1\|355824_357207_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	6.5e-32	36.0
WP_011184238.1\|357237_357792_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002990826.1\|357791_358043_+	hypothetical protein	NA	NA	NA	NA
WP_101248302.1\|358062_358758_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_032464850.1\|358908_359250_+	hypothetical protein	NA	NA	NA	NA
WP_032464851.1\|359348_359996_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_004218965.1\|360141_361074_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985780.1\|361137_361863_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_002990814.1\|361863_362718_+	metal ABC transporter permease	NA	NA	NA	NA
WP_002990808.1\|362865_363672_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_101248303.1\|363888_366294_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_010921962.1\|366363_366717_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002990800.1\|366960_367386_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002985768.1\|367491_368181_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002985765.1\|368506_369235_+	UMP kinase	NA	NA	NA	NA
WP_002985763.1\|369263_369821_+	ribosome recycling factor	NA	NA	NA	NA
WP_011284569.1\|369929_370787_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_101248304.1\|370859_371369_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_002985757.1\|371365_371581_+	YozE family protein	NA	NA	NA	NA
WP_101248305.1\|371736_372918_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.6e-16	40.5
WP_101248306.1\|373231_375004_+	oleate hydratase	NA	NA	NA	NA
WP_010921967.1\|375162_376215_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_101248307.1\|376260_376836_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_002985748.1\|376994_377492_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002985746.1\|377472_377880_+	diacylglycerol kinase	NA	NA	NA	NA
WP_002985743.1\|377999_378896_+	GTPase Era	NA	NA	NA	NA
WP_002993018.1\|378916_379393_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_014407373.1\|379698_379953_-	hypothetical protein	NA	NA	NA	NA
WP_101248308.1\|380554_381001_-	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	4.1e-12	36.0
WP_011528336.1\|381223_381934_-\|bacteriocin	bacteriocin ABC transporter	NA	NA	NA	NA
WP_002994577.1\|382038_382275_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_002994580.1\|382572_382797_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_072135613.1\|383194_383557_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_028797129.1\|384167_384395_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002994587.1\|384443_384761_+	hypothetical protein	NA	NA	NA	NA
WP_020833317.1\|384826_385108_+\|transposase	transposase	NA	NA	NA	NA
WP_111694349.1\|385140_385596_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.4e-14	34.8
WP_002987929.1\|385750_385966_+\|transposase	transposase	U5P429	Shigella_phage	7.0e-10	45.5
WP_002992578.1\|387908_388658_+	response regulator transcription factor	A0A1V0E029	Clostridioides_phage	2.1e-21	28.0
WP_014635339.1\|388658_389993_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_011017462.1\|390140_390266_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_101248309.1\|390342_391707_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_032464223.1\|391717_393871_-	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	1.7e-42	28.1
WP_030126106.1\|394147_394372_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_030126105.1\|394448_394667_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_032466306.1\|395192_395594_+	hypothetical protein	NA	NA	NA	NA
WP_011054254.1\|397006_397405_+	hypothetical protein	NA	NA	NA	NA
WP_023605037.1\|397752_398022_-	quorum-sensing system protein StcA	NA	NA	NA	NA
WP_002985713.1\|398543_398786_-	hypothetical protein	NA	NA	NA	NA
WP_128650799.1\|398935_399004_-	peptide pheromone SHP2	NA	NA	NA	NA
WP_023611572.1\|399092_399959_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_002990742.1\|400130_400958_+	DNA-formamidopyrimidine glycosylase	A0A127AWE5	Bacillus_phage	5.1e-16	27.5
WP_101248494.1\|400954_401548_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_101248310.1\|401737_403240_+	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	1.0e-75	41.9
WP_076634293.1\|403361_404555_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_002990729.1\|404551_404698_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_002985700.1\|404743_404980_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_162292737.1\|405076_407407_+	ribonuclease R	Q0GXV6	Lactococcus_phage	8.8e-90	39.8
WP_002994152.1\|407409_407877_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	5.7e-41	57.0
WP_010921981.1\|407882_408602_+	glutaminyl-peptide cyclotransferase	NA	NA	NA	NA
WP_002994169.1\|408718_409366_-	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_011184272.1\|409415_410342_-	DUF979 family protein	NA	NA	NA	NA
WP_012560521.1\|410341_411025_-	DUF969 domain-containing protein	NA	NA	NA	NA
WP_002994177.1\|411234_412161_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	2.6e-77	47.5
WP_020904973.1\|412305_412683_-	lactoylglutathione lyase	NA	NA	NA	NA
WP_002985684.1\|412693_413359_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_101248312.1\|413407_414493_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_002985680.1\|414666_415668_+	catabolite control protein A	C6ZCU4	Enterobacteria_phage	6.1e-24	28.5
WP_002985678.1\|415798_416797_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_023078780.1\|416798_418133_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_002985672.1\|418554_420498_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.0e-120	38.7

DBSCAN-SWA_3

629081 : 639685

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101248340.1\|629081_631292_-	LTA synthase family protein	W6LM83	Streptococcus_phage	5.0e-268	69.1
WP_023609837.1\|631399_632563_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	7.6e-143	64.9
WP_002985140.1\|632559_633246_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_101248341.1\|633339_634506_+	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-34	32.8
WP_002992643.1\|634566_634908_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	41.1
WP_002992646.1\|635128_636481_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	23.8
WP_002992648.1\|636560_637838_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_014407485.1\|637867_638308_-	membrane protein	NA	NA	NA	NA
WP_002985123.1\|638542_639685_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	4.1e-24	27.0

DBSCAN-SWA_4

967684 : 1095206

134

Streptococcus_phage(49.43%)

portal,transposase,terminase,integrase,holin,head,capsid,tail

attL 965988:966005|attR 1101878:1101895

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
965988:966005	attL	NA	NA	NA	NA
WP_101248385.1\|967684_970795_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	8.3e-120	29.8
WP_002989617.1\|970979_971351_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002984437.1\|971350_972049_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_002984433.1\|972058_972844_+	hypothetical protein	NA	NA	NA	NA
WP_002989607.1\|972970_973585_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
WP_011054546.1\|974175_974364_-	hypothetical protein	A3F673	Streptococcus_phage	1.2e-21	84.7
WP_021340779.1\|974478_975267_-	streptococcal pyrogenic exotoxin SpeL	Q938J1	Temperate_phage	9.1e-47	41.4
WP_014635497.1\|975548_976262_-	streptococcal pyrogenic exotoxin SpeM	Q938J1	Temperate_phage	9.0e-78	59.5
WP_011054729.1\|976564_977431_-	DUF334 domain-containing protein	Q938J2	Temperate_phage	3.7e-134	100.0
WP_011017840.1\|977418_977943_-	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_101248386.1\|978098_978743_-	CHAP domain-containing protein	Q938J4	Temperate_phage	5.2e-93	77.7
WP_002994484.1\|978852_979545_-	AP2 domain-containing protein	A0A2H4J2S8	uncultured_Caudovirales_phage	1.5e-32	34.2
WP_002994486.1\|979777_980335_-	glycoside hydrolase family 73 protein	Q938J4	Temperate_phage	2.8e-95	88.1
WP_002993358.1\|980450_980678_-\|holin	phage holin	A7J2B3	Streptococcus_phage	1.7e-30	97.3
WP_002987582.1\|980674_980950_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_030126654.1\|980965_981598_-	hypothetical protein	Q938J7	Temperate_phage	8.0e-46	51.0
WP_002983467.1\|981600_982032_-	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_002991755.1\|982043_984062_-	hypothetical protein	Q938J9	Temperate_phage	5.7e-170	71.5
WP_030126653.1\|984077_985187_-	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.6e-110	66.7
WP_030126652.1\|985186_987298_-	hypothetical protein	A3F656	Streptococcus_phage	1.3e-124	41.5
WP_002992603.1\|987294_988065_-\|tail	tail protein	A1EAB1	Streptococcus_phage	4.0e-55	44.7
WP_101248387.1\|988064_990812_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	5.4e-54	36.2
WP_002992600.1\|990812_991130_-	hypothetical protein	A0A1B1SDV4	Weissella_phage	5.9e-05	47.3
WP_002992599.1\|991150_991519_-	hypothetical protein	A0A1W6JNQ1	Staphylococcus_phage	5.2e-05	28.7
WP_002992598.1\|991567_992098_-\|tail	phage major tail protein, TP901-1 family	A1EAF4	Streptococcus_phage	3.3e-45	56.6
WP_002992597.1\|992085_992484_-	hypothetical protein	A1EAF3	Streptococcus_phage	6.4e-25	43.8
WP_002992596.1\|992480_992837_-	hypothetical protein	K4I1Q2	Lactobacillus_virus	7.5e-09	34.3
WP_002992595.1\|992836_993133_-	hypothetical protein	A0A1P8BKV3	Lactococcus_phage	3.7e-09	34.7
WP_002992594.1\|993129_993483_-	hypothetical protein	A0A2H4J002	uncultured_Caudovirales_phage	4.6e-27	53.8
WP_002992593.1\|993496_993739_-	hypothetical protein	NA	NA	NA	NA
WP_002992592.1\|993748_994825_-	hypothetical protein	A0A2H4J022	uncultured_Caudovirales_phage	1.4e-103	55.7
WP_002992591.1\|994824_995229_-\|head	head decoration protein	A0A0K2CNR0	Brevibacillus_phage	5.0e-09	36.6
WP_002992590.1\|995238_995772_-	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	1.8e-14	82.5
WP_002992589.1\|995914_996181_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	5.6e-33	83.0
WP_101248499.1\|996196_997063_-\|capsid	minor capsid protein	A1EAE3	Streptococcus_phage	3.2e-69	50.4
WP_002992587.1\|997091_998582_-\|portal	phage portal protein	C9W9H5	Streptococcus_virus	8.3e-142	53.8
WP_002992586.1\|998593_999838_-\|terminase	PBSX family phage terminase large subunit	M1PG09	Streptococcus_phage	8.7e-153	65.1
WP_032459833.1\|1000333_1000711_-	ASCH domain-containing protein	Q938L5	Temperate_phage	6.4e-67	99.2
WP_157821760.1\|1000771_1001155_-	GNAT family N-acetyltransferase	B5SP24	Lactococcus_phage	3.9e-35	58.5
WP_002995455.1\|1001163_1001841_-	hypothetical protein	Q938L6	Temperate_phage	5.6e-130	99.6
WP_030126646.1\|1001819_1002338_-	ParB N-terminal domain-containing protein	Q938L7	Temperate_phage	1.5e-87	97.7
WP_002990048.1\|1002563_1002776_+	hypothetical protein	NA	NA	NA	NA
WP_011284864.1\|1002865_1003780_-	hypothetical protein	NA	NA	NA	NA
WP_014411867.1\|1004390_1004831_-	ArpU family transcriptional regulator	Q938L8	Temperate_phage	1.9e-78	99.3
WP_030126645.1\|1005103_1005739_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.6e-89	69.4
WP_011284869.1\|1005740_1006025_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.6e-36	86.2
WP_002995955.1\|1006188_1006425_-	DUF3310 domain-containing protein	A0A097PAQ7	Streptococcus_pyogenes_phage	2.4e-40	100.0
WP_030126643.1\|1006666_1007023_-	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	6.5e-61	99.2
WP_002995960.1\|1007006_1007327_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	2.0e-53	100.0
WP_020905118.1\|1007571_1009053_-	DNA primase	A0A1P8VVM0	Streptococcus_phage	1.3e-296	100.0
WP_030126642.1\|1009042_1009855_-	hypothetical protein	A0A1P8VVM6	Streptococcus_phage	5.5e-156	99.6
WP_002995969.1\|1009857_1010316_-	DUF669 domain-containing protein	A0A1P8VVN0	Streptococcus_phage	3.8e-82	100.0
WP_030126641.1\|1010331_1011561_-	DEAD/DEAH box helicase	A0A1P8VVM2	Streptococcus_phage	1.3e-236	99.8
WP_002995975.1\|1011662_1012343_-	AAA family ATPase	A0A1P8VVS4	Streptococcus_phage	1.6e-129	100.0
WP_002995979.1\|1012343_1012826_-	siphovirus Gp157 family protein	A0A1P8VVS5	Streptococcus_phage	5.1e-77	98.1
WP_002995982.1\|1013052_1013367_-	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	1.1e-51	98.1
WP_002995988.1\|1013513_1013810_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	4.4e-47	95.9
WP_002995990.1\|1013887_1014064_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002992762.1\|1014207_1014429_+	hypothetical protein	NA	NA	NA	NA
WP_030126640.1\|1014386_1014728_-	hypothetical protein	NA	NA	NA	NA
WP_030126639.1\|1014744_1015200_-	antirepressor	A3F617	Streptococcus_phage	5.8e-14	37.9
WP_030126638.1\|1015196_1016120_-	hypothetical protein	J7KDG2	Streptococcus_phage	4.3e-48	61.3
WP_002992770.1\|1016148_1016349_-	helix-turn-helix transcriptional regulator	A0A141E205	Streptococcus_phage	2.7e-08	59.6
WP_002992773.1\|1016442_1016985_+	hypothetical protein	NA	NA	NA	NA
WP_030126637.1\|1017333_1018152_+	helix-turn-helix transcriptional regulator	A0A097PBE5	Streptococcus_pyogenes_phage	9.2e-135	94.5
WP_002990092.1\|1018186_1018867_+	hypothetical protein	A0A097PAS7	Streptococcus_pyogenes_phage	4.7e-76	88.3
WP_002984265.1\|1018999_1020088_+\|integrase	site-specific integrase	A0A097PAS9	Streptococcus_pyogenes_phage	4.2e-204	99.4
WP_101248388.1\|1020450_1021071_+	DUF3862 domain-containing protein	NA	NA	NA	NA
WP_101248389.1\|1021327_1023592_-	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
WP_101248390.1\|1023626_1025120_-	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_002992583.1\|1025234_1026254_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	5.7e-17	27.8
WP_002984246.1\|1026496_1027744_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_010922383.1\|1028017_1029379_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002984240.1\|1029378_1030215_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_101248391.1\|1031689_1032673_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_002984219.1\|1032703_1033954_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_002984216.1\|1033946_1034186_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_002994626.1\|1034203_1035460_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	NA	NA	NA	NA
WP_002989572.1\|1035456_1036995_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	6.5e-41	28.2
WP_002984200.1\|1037006_1037150_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_002989569.1\|1037413_1039405_-	excinuclease ABC subunit B	NA	NA	NA	NA
WP_063632511.1\|1039597_1041772_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_002984187.1\|1041771_1042512_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-35	42.1
WP_101248392.1\|1042808_1044188_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_003060495.1\|1044365_1044815_-	DUF3284 domain-containing protein	NA	NA	NA	NA
WP_002989549.1\|1044811_1045147_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_014635542.1\|1045149_1045461_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_063632512.1\|1045483_1047478_-	BglG family transcription antiterminator	NA	NA	NA	NA
WP_010922396.1\|1047583_1048678_-	DUF871 domain-containing protein	NA	NA	NA	NA
WP_021775403.1\|1048686_1050087_-	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_011285592.1\|1050311_1051007_+	nicotinamide riboside transporter PnuC	NA	NA	NA	NA
WP_023609807.1\|1051238_1052552_-	GTPase ObgE	NA	NA	NA	NA
WP_002984145.1\|1052608_1052737_-	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_101248500.1\|1053089_1054320_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.8e-63	49.4
WP_002992869.1\|1054620_1055493_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_101248393.1\|1055716_1057027_+	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
WP_136287598.1\|1057104_1057398_+\|transposase	transposase	NA	NA	NA	NA
WP_136127639.1\|1057346_1057886_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.8e-15	35.5
WP_136104835.1\|1057920_1058154_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	2.4e-11	47.1
WP_011017915.1\|1058170_1058902_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_011017916.1\|1059016_1059382_+	thioesterase family protein	NA	NA	NA	NA
WP_014407647.1\|1059501_1060722_-	MFS transporter	NA	NA	NA	NA
WP_002995506.1\|1061095_1062580_+	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_002984115.1\|1062684_1063086_-	PaaI family thioesterase	NA	NA	NA	NA
WP_101248394.1\|1064100_1065780_-	recombinase family protein	A0A2I4R675	Erysipelothrix_phage	6.7e-31	26.4
WP_030127072.1\|1066515_1066926_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_030127073.1\|1067193_1069713_-	ABC transporter permease	NA	NA	NA	NA
WP_078136843.1\|1069705_1070161_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.0e-23	40.0
WP_001291561.1\|1070320_1071538_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|1071619_1071823_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|1072283_1072514_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_024052573.1\|1072510_1072933_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	1.3e-71	99.3
WP_101248396.1\|1073437_1073821_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.8e-24	100.0
WP_101248397.1\|1073869_1075243_-	tetracycline efflux MFS transporter Tet(L)	NA	NA	NA	NA
WP_000336323.1\|1075414_1075582_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_101248398.1\|1075700_1077620_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	98.9
WP_001791010.1\|1077635_1077752_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224319.1\|1077996_1078929_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
WP_000769868.1\|1078925_1079927_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|1079923_1082101_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000331160.1\|1082103_1084551_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|1084534_1085041_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|1085015_1085513_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|1085629_1085851_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|1085893_1087099_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|1087121_1087274_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|1087276_1088662_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|1088690_1089077_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|1089092_1089407_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_030127077.1\|1090079_1090931_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	1.1e-08	24.6
WP_101248399.1\|1090934_1091591_-	response regulator transcription factor	NA	NA	NA	NA
WP_030127079.1\|1091611_1091839_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_030127080.1\|1092133_1092490_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_101248400.1\|1093328_1095206_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	9.4e-26	28.3
1101878:1101895	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP021640

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection