CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018867	Lactobacillus alimentarius DSM 20249 chromosome, complete genome	1 crisprs	DEDDh,csa3,DinG,cas14j,cas3,RT	0	0	4	0
NZ_CP018868	Lactobacillus alimentarius DSM 20249 plasmid pLDW-11, complete sequence	0 crisprs	NA	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018867_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018867_1

803074-803221

Orphan

Consensus_repeat	Method
AGAATCATCCCTATATACATAGGGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP018867_1

>merge|NZ_CP018867|1|803074-803221|CRISPRCasFinder
GGAATCATCCCTATACACATAGGGAAACACGCAACTAGGGAACGTCATAGACATCTGTGGCGAGAATCATCCCTATATACATAGGGAACACCCGGAGAACGTCATGGAAAAGATTTACCCCATAGAATCATCCCTATATACATAGGGA

>NZ_CP018867|1|1|803074-803221|CRISPRCasFinder
GGAATCATCCCTATACACATAGGGA	AACACGCAACTAGGGAACGTCATAGACATCTGTGGCG
AGAATCATCCCTATATACATAGGGA	ACACCCGGAGAACGTCATGGAAAAGATTTACCCCAT
AGAATCATCCCTATATACATAGGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018867.1\|WP_057740167.1\|812386_813094_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|181800
NZ_CP018867.1\|WP_057740199.1\|798387_799119_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NZ_CP018867.1\|WP_057740191.1\|800229_801036_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP018867.1\|WP_057740188.1\|801159_801444_-\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198403
NZ_CP018867.1\|WP_057740172.1\|811456_812131_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NZ_CP018867.1\|WP_057740203.1\|797085_797829_-\|isoprenyl-transferase	unknown	unknown	gnl\|CDD\|184840
NZ_CP018867.1\|WP_057740174.1\|809237_811457_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP018867.1\|WP_057740182.1\|804705_806250_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP018867.1\|WP_057740207.1\|794994_796257_-\|RIP-metalloprotease-RseP	unknown	unknown	gnl\|CDD\|272878
NZ_CP018867.1\|WP_057740205.1\|796276_797071_-\|phosphatidate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|366491
NZ_CP018867.1\|WP_057740193.1\|799288_800164_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP018867.1\|WP_057740163.1\|814220_814706_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|376377
NZ_CP018867.1\|WP_057740178.1\|806823_807843_-\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP018867.1\|WP_057740165.1\|813097_814228_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP018867.1\|WP_057740184.1\|802224_802854_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|223282
NZ_CP018867.1\|WP_057740186.1\|801433_802162_-\|tRNA1(Val)-(adenine(37)-N6)-methyltransferase	unknown	unknown	gnl\|CDD\|226608
NZ_CP018867.1\|WP_057740170.1\|812131_812377_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl\|CDD\|376904
NZ_CP018867.1\|WP_057740180.1\|806227_806827_-\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|187714
NZ_CP018867.1\|WP_057740176.1\|807855_809262_-\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NZ_CP018867.1\|WP_057740201.1\|797837_798395_-\|ribosome-recycling-factor	unknown	unknown	gnl\|CDD\|178850

Protein	Function_ID	Function_description	E-value
NZ_CP018867.1\|WP_057740167.1\|812386_813094_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|181800	PRK09362, PRK09362, phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed.	2.17289e-129
NZ_CP018867.1\|WP_057740199.1\|798387_799119_-\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	1.69013e-151
NZ_CP018867.1\|WP_057740191.1\|800229_801036_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	6.92364e-168
NZ_CP018867.1\|WP_057740188.1\|801159_801444_-\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198403	cd10456, GIY-YIG_UPF0213, The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1. This family contains a group of uncharacterized proteins found mainly in bacteria and several in dsDNA viruses. Although their function roles have not been recognized, these proteins show significant sequence similarities with the N-terminal GIY-YIG endonuclease domain of structure-specific endonuclease subunit SLX1, which binds another structure-specific endonuclease subunit SLX4 to form an active heterodimeric SLX1-SLX4 complex. This complex functions as a 5' flap endonuclease in yeast, and has also been identified as a Holliday junction resolvase in human.	9.47623e-36
NZ_CP018867.1\|WP_057740172.1\|811456_812131_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	8.37981e-146
NZ_CP018867.1\|WP_057740203.1\|797085_797829_-\|isoprenyl-transferase	gnl\|CDD\|184840	PRK14830, PRK14830, undecaprenyl pyrophosphate synthase; Provisional.	6.67149e-149
NZ_CP018867.1\|WP_057740174.1\|809237_811457_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP018867.1\|WP_057740182.1\|804705_806250_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP018867.1\|WP_057740207.1\|794994_796257_-\|RIP-metalloprotease-RseP	gnl\|CDD\|272878	TIGR00054, Putative_zinc_metalloprotease_slr1821, RIP metalloprotease RseP. Members of this nearly universal bacterial protein family are regulated intramembrane proteolysis (RIP) proteases. Older and synonymous gene symbols include yaeL in E. coli, mmpA in Caulobacter crescentus, etc. This family includes a region that hits the PDZ domain, found in a number of proteins targeted to the membrane by binding to a peptide ligand. The N-terminal region of this family contains a perfectly conserved motif HEXGH as found in a number of metalloproteinases, where the Glu is the active site and the His residues coordinate the metal cation. Membership in this family is determined by a match to the full length of the seed alignment; the model also detects fragments as well matches a number of members of the PEPTIDASE FAMILY S2C. The region of match appears not to overlap the active site domain. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.56274e-83
NZ_CP018867.1\|WP_057740205.1\|796276_797071_-\|phosphatidate-cytidylyltransferase	gnl\|CDD\|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	7.00815e-63
NZ_CP018867.1\|WP_057740193.1\|799288_800164_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.31327e-153
NZ_CP018867.1\|WP_057740163.1\|814220_814706_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	1.85231e-81
NZ_CP018867.1\|WP_057740178.1\|806823_807843_-\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	1.41374e-166
NZ_CP018867.1\|WP_057740165.1\|813097_814228_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	1.80063e-178
NZ_CP018867.1\|WP_057740184.1\|802224_802854_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|223282	COG0204, PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism].	1.58433e-38
NZ_CP018867.1\|WP_057740186.1\|801433_802162_-\|tRNA1(Val)-(adenine(37)-N6)-methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	6.33644e-77
NZ_CP018867.1\|WP_057740170.1\|812131_812377_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl\|CDD\|376904	pfam02700, PurS, Phosphoribosylformylglycinamidine (FGAM) synthase. This family forms a component of the de novo purine biosynthesis pathway.	1.02965e-28
NZ_CP018867.1\|WP_057740180.1\|806227_806827_-\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|187714	cd08645, FMT_core_GART, Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART). Phosphoribosylglycinamide formyltransferase, also known as GAR transformylase or GART, is an essential enzyme that catalyzes the third step in de novo purine biosynthesis. This enzyme uses formyl tetrahydrofolate as a formyl group donor to produce 5'-phosphoribosyl-N-formylglycinamide. In prokaryotes, GART is a single domain protein but in most eukaryotes it is the C-terminal portion of a large multifunctional protein which also contains GAR synthetase and aminoimidazole ribonucleotide synthetase activities.	1.75354e-84
NZ_CP018867.1\|WP_057740176.1\|807855_809262_-\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NZ_CP018867.1\|WP_057740201.1\|797837_798395_-\|ribosome-recycling-factor	gnl\|CDD\|178850	PRK00083, frr, ribosome recycling factor; Reviewed.	3.53731e-97

>NZ_CP018867.1|WP_057740184.1|802224_802854_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MFYKFIRVIARGIVFILNGRYKVVGKENLPDKPFILVAPHRTWWEPIFFALVISPREATFMAKKELFKNPILRFILVHAHAFPVDRAHPGPSVIKTPVKALKKEDKVLIMFPSGTRYSEQLKGGASLIAKLSKAPLVPFVYQGPLSFSDLMKHKQITIGVGPEIDFDFKAKLDEKQTKQINDDMEKAWDKIDDEIDPSFEYIPPKKKNK
>NZ_CP018867.1|WP_057740186.1|801433_802162_-|tRNA1(Val)-(adenine(37)-N6)-methyltransferase
MSIYSQDIISHSGIIINQDKKLYSFNLDTILLYNFAKTVKKGKIVDLCSGNGAIGLSLASKTKAQIYLVEIQKKLAELSQKSIVDNNLEQQVHLINDDLKNVQKHIDHDTVDMLVCNPPYFKVSDQTPLKENPVLAIARHELKANLEDILYSIKVLLKENSHAYLVYRPERLSELLSLMLQQRLQPKRIRFVRTSTQKDANFVLLDVIKTVKEASLRVEPDLIIYDEKHHLTKEANQIINGN
>NZ_CP018867.1|WP_057740188.1|801159_801444_-|GIY-YIG-nuclease-family-protein
METSKYYVYILLCNDKTFYTGTSNNVKKRVATHNAGKGAKYTKTRRPVKLMYTEELENKSQALKREIAIKKLSRLQKENLLKSNGINWRDYLIS
>NZ_CP018867.1|WP_057740191.1|800229_801036_-|30S-ribosomal-protein-S2
MSVISMKQLLEAGVHFGHQTRRWNPKMKPFIFTQRNGIYIIDLQKTVRMIDDAYNYMKAVAGDDGIFLFVGTKKQAQDSIAEEATRAGQYYVNHRWLGGTLTNWNTIQKRIKRLKDIKAMSQDGTFDRLPKKEVALLEKQQAKLEKFLGGIEDMPRIPDVMFIVDPHKENIAVNEAKKLNIPIVAMVDTNTDPDPIDVIIPSNDDAIRAVRLITSKMADAIVEGKQGEEAVTDADFAKDDKKDENSDAADAKSIEDLAEAKNNNEDNK
>NZ_CP018867.1|WP_057740193.1|799288_800164_-|elongation-factor-Ts
MAKITAAQVKELRDKTSVGMMDAKKALVAADGNMQEAIDKLREKGIAKAAKKSGNIAAEGLAHIEISGNKAAIIEVNSETDFVSSNDKFINLVNEIGKVIVTNEPKDMDEALALKIGDQTVNDAITGLTAVIGEKISLRRFQVLDKTDSQVFGSYLHNGGLIGAIVTLEGKDEDAAKDVAMHVAAINPEYMDRDQVPADRLEHEKAIFTEETKAEGKPEKIIPRIVEGRVNKYLSEISLADQEFVKDSDMTVQQFVESKNSKLVSFVRYEVGEGIEKKQEDFAEEVKNQMK
>NZ_CP018867.1|WP_057740199.1|798387_799119_-|UMP-kinase
MPDIKYKRVILKVSGEALAGEKGFGINPPVIKQIAEQIKSVHDLGVQVAIVCGGGNIWRGETGAEMGMDRAQADYMGMMATVMNGLALQDGLEHIGVPTRVQTSIEMRQVAEPYIRRKAIRHLEKGRVVIFAGGTGNPYFSTDTTSVLRAAEIEADVILMAKNNVDGVYSADPKKDPNAKKYAELTQLDIINKNLGVMDTTASSLSMDNDIPLIVFNLNKPENIKKVVQGENIGTIIKGGNDD
>NZ_CP018867.1|WP_057740201.1|797837_798395_-|ribosome-recycling-factor
MTNKAVSKAKENMSKSIDVLRKELANIRAGKANASILSNVKVSYYGTDVPLNQVASINIPEARVLMITPYDKSSLDDIEHAINSSDLGLNPANDGSVIRLVIPQLTGERRKEIAKQVGKEAEESRIAVRNVRREAMDDLKKQLKANEVTEDEFHDVEDQVQKVTDSAIADVDKLAAAKEKEITEG
>NZ_CP018867.1|WP_057740203.1|797085_797829_-|isoprenyl-transferase
MTDDSKRQLDPDILVPKHIAIIMDGNGRWAKRKGQPRIAGHKQGMNNVKTIATAASHLGVKVLSLYAFSTENWSRPSKEVNFLMKLPVDFFGTFMPDLIKENIQVFVTGFTDHLPEKTRKVVLKAVEDTKDNTGMILNFAFNYGGRAEIVNAAKNLAIEAASGSIDPNEIDDSMFSDHLLTNQLKDLADPDLLIRTSGEERISNFMLWQLAYTEMIFDDSYWPDFSVADLVEDIKEFDRRDRRFGSV
>NZ_CP018867.1|WP_057740205.1|796276_797071_-|phosphatidate-cytidylyltransferase
MKQRVITAVIALAIFIPILLAGGVWLEVAAAALAAVGVFEIYIMRKRIIVSFDFLVTILGTLALVVPNGFYQGWFPKSISRLDLFYVFAVILLIITVLTKNKFNFEDAGVSIVAMLYIGTGFHYLAAVRNSQPGLGLLMYALIVVWSTDIFAYTFGRKIGKHKLWPAISPNKTWEGTIAGIIMALILSGIYMIFVPQEYSMTTMLIIAFVLSIMGQMGDLIESAYKRYYKVKDSGNILPGHGGILDRFDSMLIVLPLLHIFGLV
>NZ_CP018867.1|WP_057740207.1|794994_796257_-|RIP-metalloprotease-RseP
MTAIITFIIVFGILVIVHEFGHYYAAKKSGILVREFSVGMGPKIVAYRKNHTTYTLRLLPLGGYVRMAGAQEDDSDIQPGTMASLVLNNQNKVTKIITSSKVYDANAVPVQISKSDLVDDLEIEGYENGDESVVKKYSVDHDATIVEEDGTEVQIAPRDVQLQSVSVWKRMITNFAGPFNNFILAVLAAILAAFMMNGVATNQLGHIEKNSIAQQAGLKVNDTILSVNGKSTGSWTALSTNIQNNPGKRVSLKVKSSDKVRTVKLTPKSVKSQGQSFGFIGIMPKRDSSIGAKIKYGFSYSWGTTVAVFHALGKMVSGGFNINQLSGPVGIYSMTSQVASQGLVNIILFTSMLSMNLGIVNLIPIPALDGGKILLNIVEAIRRKPIPEQYETVITLIGVGILVLLMIAVTWNDIQRFFIK
>NZ_CP018867.1|WP_057740182.1|804705_806250_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MMKRALISVSDKTGVVEFAKGLINNGFEIVSTGGTYKKLQENDVKVIEIDEITKFPEILDGRVKTLHPMVHAGLLAKRDNAEHMKTLEKLNIQMIDLVCVNLYPFKETISKENVTPEQAIEQIDIGGPSMIRSASKNFKSVYVVIDNNDYQTVLNSIENNSDDLALRQKLAAKAFRHTAEYDSIIAHYLSDLNGEEFPDVEVLGYDFHQELRYGENSHQKAAFYQSAMPSDYSIASAKQLHGKELSFNNIKDADAALRIVADFDKPCVAALKHMNPCGIGVDDESIYQAWRKAYTADTMSIFGGIVAVNREVTKEIAEEMHKIFLEIVIAPSFTAEALEILEAKKNIRLMTLDFSKAQEADKHEYVSVMGGLLVQERDTTVDKIDEFKVVTKKAPTKEEMKALLFGQQVVKHVKSNAIVITTTDKTLGVGAGQMNRIGSVKIAIEQEELADEHAPLIMASDAFFPMDDCVQYAAEHGITAIIQPGGSIKDQDSIDMADKFGIAMVFTGRRHFKH
>NZ_CP018867.1|WP_057740180.1|806227_806827_-|phosphoribosylglycinamide-formyltransferase
MKVAIFASGNGSNFESIASSEELKKLGLEIEILVCDQPQAQVLQRAKNHHIKTFVNKLSDYNNRSEYEKAIVEKLKPLEVEYILLAGYMRVVTKTLLSNYPNRIINIHPSLLPKYSGLEAIHRAFLANEPVTGVTIHYIDEGVDTGPIIKQSKVVRLQDDTETRLESRIHQTEHQMYRAVVRDLLIKNNGVVNNEKSIN
>NZ_CP018867.1|WP_057740178.1|806823_807843_-|phosphoribosylformylglycinamidine-cyclo-ligase
MTNPYQDAGVNVESGYKISKFVKQNTHSKSIGNFGGVYEIPMGFKHPVLVSSDDGVGTKLLLTNELRKWDTIGIDCVAMCVNDILAQGAIPQYFLDYISTGKVNQKVEMILKGVIAGCKQADAALIGGETAEMPGVYGENDYDIAGFAVGICEKDELLTKKRVELGDVLIGITSSGIHSNGYSLVRKIFFQEHDFNVETRLPEFPNQKLGDILLEPTKIYTQELVPLLKQRLVKGIAHITGGGFYENVPRILPDDLGAEINVDIWPELPIFQALQKYGQLQLSDMYHIFNMGLGIVLAVDPKNEIEVLNQLNQSETLAYTIGSVVKRKTDSLILKGEKL
>NZ_CP018867.1|WP_057740176.1|807855_809262_-|amidophosphoribosyltransferase
MFDEVKSLNEECGIFGVWGAKDANYLTYLGLHSLQHRGQEGAGIVANDGQKLRAYRNLGLLTQVFSKPEYLNSLLGNSAIGHVRYSTAGENKIENVQPLLFDFTDSQLALAHNGNLTNADTLKKELEKDGHIFKSSSDSEVLVHLIKQSQKSTFHEQIVEALNKIQGGFAYLLLTKNELIVALDSHGFRPVSIGKLKTGGYVVASETCALDAVGATFYRDVKPGELITINDKGVKIDHWTTKTQLAICSMEYVYFARPDSNILGINVHSARKRMGAILAKEFPAPGDIVVGVPNSSLSAASGYAEASGLPYEMGLIKNQYMGREFIQPTQELREKSVRQKLAAVKGVVSGKRVILVDDSIVRGTTCAYIVQMLKEAGALEVHLRIASPRFMHPCFYGIDIQEKSELIAAHKSVEEMNQIFGSDSLQFLSEKGLISAIGLKADAPYSGLDMSYFNGDYPTYLYDYESKK
>NZ_CP018867.1|WP_057740174.1|809237_811457_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MIEPTAKEIKDSKLYQKWGLSDTEYQLICEKILNRLPNYTETGLYSVMWSEHCSYKNSKKVLRKMPNKSDRVLAGPGEDAGILDIGDGQAVVFKAESHNHPSAVEPYQGAATGVGGIIRDIFSMGAEPIALLNSLKFGPLDNGKTKHLVDEVVAGIGGYGNCIGLPTVGGEISFEKCYENNPLVNAMCVGLLNKTDFKHGTASGEGNLIVYVGAKTGRDGIHGATFASDEFTDTKNKQRSAVQVGNPFIEKLLMDACVEIIEQHPEWVLGIQDMGAAGLVSSTAEMASKAGSGLVLKLDDVPQRETEMSAYEMMLSESQERMVLCIKPQFKTKVLDFFKHFELDAVVIGHVTADKQYKIYHHEKLVTDIPVESLTEDVPEYDRPEIEPKRIKENQSYHFQPQIESLENTWQEMLQRPNIASKRHFYQTYDAQVKANTLITPGSDAGVIRIRGTKKAIAMTNDSNSKYVYLNPYVGGQIAVMEAARNIVASGGQPIGITDCLNYGNPENPEVFWELDKSVEGIASACREIDTPVISGNVSLYNEYNDEAIYPSPMIGMVGLIDDLQKVTTIAFKNATDLIYLVGKTTDDYNGSEIQLQQTGSIKGDLSPLDLNKEKLHQDLIHQAITRNLVASCHDLSEGGLAVALSESAFENKLGFEIKTSLTNAQMFSETQSRFLVSIRPENKQAFEDLIQQDFELLGQVTNETDFKVATSDTSVSINGMEALNNWKGAISCLMKSKA
>NZ_CP018867.1|WP_057740172.1|811456_812131_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKFAVVNFPGSNCDMDLYYAIKDGINEEAELVDYRQKSLNGFDGVLIPGGFSYGDYLRSGAIAVHAPIISEIIRFANEGKIVLGICNGFQILTELHLLPGALIQNEKSRFICETTTLIVENNRTAFTNQYEKDQRLQIPVAHGEGRYFCDEKTLKSLQENEQIVFRYDKNINGSVQQIAGVTNKRKNVLGMMPHPERAMEQILGSDDGLKLFQSIINYQVRVNN
>NZ_CP018867.1|WP_057740170.1|812131_812377_-|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MKLVKVYVTLKTSVLDAQGEAIKSAIQTMGYDHVSQVSMGKYFELRFDDYSQLDQDVDAICDELLTNPNIETYRYEIVEEK
>NZ_CP018867.1|WP_057740167.1|812386_813094_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MAENKLLYEGKAKNVYQTENDDELLMVYKDQATAFNGKKKEELPGKGVLDCQISALVFDYLIKNGIETHLIKNLSDHEQLVKSSEVFPLEVVLRNITSGSLVKKFQVESGLRLSDPIIEFYYKSDALDDPFINDSQVKALRIANDEEIAFIKQMTLKINQLLVPFFSKSGFDLVDFKLEFGKVNGKIILVDEFSPDNCRLWDKKSHDSMDKDVFRKHEGDLVKTYLEVLKRLAMR
>NZ_CP018867.1|WP_057740165.1|813097_814228_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MNKAILPGSTIGIIGGGQLGQMMALSAKEMGYKVIILDPTANCPAAQVSDDQIVANYDDLEKLIALAKRCDVLTYEFENVDAETIAEVKKYTQVPQGTKALSITQNRILEKNFIEENDFRTVPHVVIKNIFEYHRAIEKLQAPVIIKTITGGYDGKGQILVTDPENVCFAEIEHLLMQGPCLVEKKINLKKEVSVVVSANSQGQTSVFPVIENIHRDNILHLSNCPAAISSKASQLIYQIGEKLAQNLELVGTMCIEFFISTDDEVFVNEIAPRPHNSGHLTIEACNVSQFEAHIRGVCNLAMPKVELLKSAVMVNLLGQHLLKAKEELPDHAGWHFHDYGKAEIKNNRKMGHITILTEKIEQEKQAIDKNLIWDV
>NZ_CP018867.1|WP_057740163.1|814220_814706_-|5-(carboxyamino)imidazole-ribonucleotide-mutase
MNDVAVVMGSISDLKIMQNTLDVLKELQVSYEVKVISAHRMPQEMLNFANNAENNGFKVIVAGAGGAAHLPGMIASSTSLPVIGVPVPSKYLKGMDSLLSIVQMPAGVPVATVSIGEAGAKNAAILATKICALNNRQYAISLEDYVQAMHDQSLESGKNLE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

409268 : 414550

Staphylococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057739374.1\|409268_409997_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A2P9FI75	Pseudomonas_phage	5.0e-07	28.3
WP_101836857.1\|410340_411372_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	3.7e-40	34.6
WP_057739375.1\|411372_411972_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	7.9e-19	36.8
WP_057739376.1\|411961_413164_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	8.3e-92	47.2
WP_057739377.1\|413165_413636_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.2e-27	44.3
WP_083477952.1\|413704_414550_-	aldo/keto reductase	A0A1V0SDE7	Indivirus	3.9e-11	25.0

DBSCAN-SWA_2

804705 : 814706

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057740182.1\|804705_806250_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.1e-71	47.1
WP_057740180.1\|806227_806827_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.3e-25	35.9
WP_057740178.1\|806823_807843_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FC27	Synechococcus_phage	2.0e-62	41.6
WP_057740176.1\|807855_809262_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	5.4e-50	30.7
WP_057740174.1\|809237_811457_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	7.2e-142	40.5
WP_057740172.1\|811456_812131_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_057740170.1\|812131_812377_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_057740167.1\|812386_813094_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
WP_057740165.1\|813097_814228_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_057740163.1\|814220_814706_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.1e-22	47.3

DBSCAN-SWA_3

1782613 : 1790689

Enterococcus_phage(42.86%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101836852.1\|1782613_1783513_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.0e-38	34.2
WP_101836851.1\|1783509_1784043_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_057738117.1\|1784120_1785146_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	9.4e-121	66.5
WP_057738115.1\|1785161_1787327_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.2e-250	59.7
WP_057738113.1\|1787313_1787688_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	1.2e-12	35.8
WP_057738111.1\|1787693_1787924_-	glutaredoxin-like protein NrdH	A0A249XUR7	Enterococcus_phage	4.7e-12	47.3
WP_057738109.1\|1788201_1788828_+	hypothetical protein	NA	NA	NA	NA
WP_057738107.1\|1788886_1789093_-	hypothetical protein	NA	NA	NA	NA
WP_057738105.1\|1789178_1789736_+	guanylate kinase	A0A1W6JK60	Lactococcus_phage	2.2e-15	28.6
WP_057738102.1\|1789948_1790689_+	C40 family peptidase	A0A0A8WIF2	Clostridium_phage	1.3e-15	41.3

DBSCAN-SWA_4

2007149 : 2018083

Bacillus_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057738972.1\|2007149_2008667_+	AMP-binding protein	Q75ZG1	Hepacivirus	4.6e-31	29.9
WP_057738971.1\|2008663_2009641_+	aliphatic sulfonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_057738970.1\|2009767_2010181_-	hypothetical protein	NA	NA	NA	NA
WP_057738969.1\|2010177_2010432_-	hypothetical protein	NA	NA	NA	NA
WP_057738968.1\|2010504_2011011_+	helix-turn-helix transcriptional regulator	X2CXD8	Lactobacillus_phage	2.9e-06	36.1
WP_057738967.1\|2011243_2011972_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.4e-31	39.4
WP_057738966.1\|2011971_2012781_-	ABC transporter permease subunit	G3M9Y4	Bacillus_virus	1.3e-19	26.7
WP_057738965.1\|2012784_2014287_-	AMP-binding protein	A0A1V0SBX8	Catovirus	4.9e-17	23.9
WP_101836855.1\|2014483_2015383_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.9e-38	34.2
WP_101836880.1\|2015379_2015913_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_057739023.1\|2016005_2017394_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.1e-26	29.8
WP_057739022.1\|2017390_2018083_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.9e-33	34.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP018868

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

10753 : 62342

Staphylococcus_phage(35.71%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057738193.1\|10753_12025_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	9.2e-41	31.4
WP_057738164.1\|12307_13483_+\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	2.6e-26	28.8
WP_101836923.1\|15476_16263_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_057738140.1\|16250_16610_-	hypothetical protein	NA	NA	NA	NA
WP_056945266.1\|16788_18039_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	7.9e-45	32.5
WP_057738138.1\|18188_19247_-	hypothetical protein	NA	NA	NA	NA
WP_057738135.1\|19343_19673_-	hypothetical protein	NA	NA	NA	NA
WP_057738133.1\|19933_20689_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	4.3e-139	98.8
WP_014081540.1\|20742_20994_-\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	6.0e-37	95.2
WP_101836925.1\|21066_21186_-	hypothetical protein	NA	NA	NA	NA
WP_057738131.1\|21203_21446_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_057738128.1\|23049_24390_+	amino acid permease	NA	NA	NA	NA
WP_057738125.1\|24706_27421_-	hypothetical protein	NA	NA	NA	NA
WP_101836926.1\|27848_31016_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.5e-20	22.9
WP_057738192.1\|31029_32652_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	4.3e-128	50.5
WP_057738191.1\|32641_33874_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	6.6e-12	32.7
WP_083477899.1\|33924_34104_-	hypothetical protein	NA	NA	NA	NA
WP_057738190.1\|34020_34209_+	hypothetical protein	NA	NA	NA	NA
WP_057738189.1\|34305_35430_-	hypothetical protein	NA	NA	NA	NA
WP_003679901.1\|35433_35649_-	hypothetical protein	NA	NA	NA	NA
WP_057738188.1\|35770_37906_-	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	2.0e-109	47.0
WP_003660151.1\|37912_38323_-	hypothetical protein	NA	NA	NA	NA
WP_057738187.1\|38337_39177_-	hypothetical protein	NA	NA	NA	NA
WP_057738186.1\|39195_39585_-	hypothetical protein	NA	NA	NA	NA
WP_057738184.1\|39596_41150_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_057738183.1\|41165_41555_-	hypothetical protein	NA	NA	NA	NA
WP_057738182.1\|41551_42037_-	hypothetical protein	NA	NA	NA	NA
WP_057738181.1\|42037_42406_-	thioredoxin family protein	NA	NA	NA	NA
WP_057738180.1\|42392_43010_-	hypothetical protein	NA	NA	NA	NA
WP_057738179.1\|43023_44178_-	CHAP domain-containing protein	A0A1X9I9Q1	Staphylococcus_phage	1.3e-14	38.1
WP_057738178.1\|44178_45597_-	conjugal transfer protein	NA	NA	NA	NA
WP_057738176.1\|45589_47605_-	DUF87 domain-containing protein	NA	NA	NA	NA
WP_016381866.1\|47616_48276_-	hypothetical protein	NA	NA	NA	NA
WP_057738174.1\|48244_48607_-	hypothetical protein	NA	NA	NA	NA
WP_057738172.1\|48627_48963_-	conjugal transfer protein	NA	NA	NA	NA
WP_020967646.1\|48964_49579_-	hypothetical protein	NA	NA	NA	NA
WP_082272744.1\|49617_49926_-	hypothetical protein	NA	NA	NA	NA
WP_057738170.1\|50009_52070_-	MobA/MobL family protein	NA	NA	NA	NA
WP_057738168.1\|52339_52549_+	hypothetical protein	NA	NA	NA	NA
WP_041095822.1\|52571_52850_+	hypothetical protein	NA	NA	NA	NA
WP_010012556.1\|52839_53520_-	AAA family ATPase	NA	NA	NA	NA
WP_010620892.1\|53516_53702_-	hypothetical protein	NA	NA	NA	NA
WP_010014831.1\|53748_54030_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_010014830.1\|54256_55336_-	replication initiator protein A	NA	NA	NA	NA
WP_002825834.1\|55942_56191_-	hypothetical protein	NA	NA	NA	NA
WP_010010267.1\|56204_57011_-	ParA family protein	A0A1V0DZZ0	Clostridioides_phage	2.3e-21	30.1
WP_034528490.1\|57107_57701_-	recombinase family protein	M4QQC6	Vibrio_phage	4.6e-19	42.4
WP_057738166.1\|58122_59328_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_057738193.1\|59612_60884_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	9.2e-41	31.4
WP_057738164.1\|61166_62342_+\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	2.6e-26	28.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018867

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP018868

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection