CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018039	Bordetella pertussis strain J294 chromosome, complete genome	5 crisprs	csa3,cas3,DinG,DEDDh	0	0	24	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018039_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018039_1

250584-250668

Orphan

Consensus_repeat	Method
GGTGCCTGTCCCCGCGGGGACAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018039_1

>merge|NZ_CP018039|1|250584-250668|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAGATACCGTCTTGGCCGTCAAGCGTTCATGGCGTATGACAGGGTGCCTGTCCCCGCGGGGACAG

>NZ_CP018039|1|1|250584-250668|CRISPRCasFinder
GGTGCCTGTCCCCGCGGGGACAG	ATACCGTCTTGGCCGTCAAGCGTTCATGGCGTATGACAG
GGTGCCTGTCCCCGCGGGGACAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018039.1\|WP_010929701.1\|246030_246522_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|172582
NZ_CP018039.1\|WP_010929705.1\|251616_253506_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630
NZ_CP018039.1\|WP_010929709.1\|259949_260849_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176107
NZ_CP018039.1\|WP_003814358.1\|239541_240285_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP018039.1\|WP_003814356.1\|240328_241372_-\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270320
NZ_CP018039.1\|WP_010929707.1\|256377_257769_+\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NZ_CP018039.1\|WP_010929708.1\|257785_258766_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NZ_CP018039.1\|WP_010929704.1\|248569_249271_-\|DnaA-regulatory-inactivator-Hda	unknown	unknown	gnl\|CDD\|236347
NZ_CP018039.1\|WP_010929703.1\|247874_248573_-\|HAD-IB-family-hydrolase	unknown	unknown	gnl\|CDD\|319796
NZ_CP018039.1\|WP_003814332.1\|253592_254231_+\|membrane-protein	unknown	unknown	gnl\|CDD\|182775
NZ_CP018039.1\|WP_019247543.1\|254373_255759_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|182376
NZ_CP018039.1\|WP_003814351.1\|245055_246012_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270296
NZ_CP018039.1\|WP_003814321.1\|260955_262710_+\|gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|223482
NZ_CP018039.1\|WP_003814339.1\|249523_250573_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP018039.1\|WP_003814363.1\|238109_238520_+\|4-carboxymuconolactone-decarboxylase	unknown	unknown	gnl\|CDD\|131478
NZ_CP018039.1\|WP_010929706.1\|255689_256226_-\|bifunctional-alanine-racemase/tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl\|CDD\|223873
NZ_CP018039.1\|WP_003814337.1\|250678_251620_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NZ_CP018039.1\|WP_010929702.1\|246518_247874_-\|polynucleotide-adenylyltransferase-PcnB	unknown	unknown	gnl\|CDD\|130997
NZ_CP018039.1\|WP_003814324.1\|258901_259885_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein-BugE	unknown	unknown	gnl\|CDD\|270295
NZ_CP018039.1\|WP_003814355.1\|241542_243645_+\|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl\|CDD\|129868

Protein	Function_ID	Function_description	E-value
NZ_CP018039.1\|WP_010929701.1\|246030_246522_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|172582	PRK14092, PRK14092, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.	2.78166e-87
NZ_CP018039.1\|WP_010929705.1\|251616_253506_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
NZ_CP018039.1\|WP_010929709.1\|259949_260849_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176107	cd08415, PBP2_LysR_opines_like, The C-terminal substrate-domain of LysR-type transcriptional regulators involved in the catabolism of opines and that of related regulators, contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate-domain of LysR-type transcriptional regulators, OccR and NocR, involved in the catabolism of opines and that of LysR for lysine biosynthesis which clustered together in phylogenetic trees. Opines, such as octopine and nopaline, are low molecular weight compounds found in plant crown gall tumors that are produced by the parasitic bacterium Agrobacterium. There are at least 30 different opines identified so far. Opines are utilized by tumor-colonizing bacteria as a source of carbon, nitrogen, and energy. NocR and OccR belong to the family of LysR-type transcriptional regulators that positively regulates the catabolism of nopaline and octopine, respectively. Both nopaline and octopalin are arginine derivatives. In Agrobacterium tumefaciens, NocR regulates expression of the divergently transcribed nocB and nocR genes of the nopaline catabolism (noc) region. OccR protein activates the occQ operon of the Ti plasmid in response to octopine. This operon encodes proteins required for the uptake and catabolism of octopine. The occ operon also encodes the TraR protein, which is a quorum-sensing transcriptional regulator of the Ti plasmid tra regulon. LysR is the transcriptional activator of lysA gene encoding diaminopimelate decarboxylase, an enzyme that catalyses the decarboxylation of diaminopimelate to produce lysine. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.62875e-38
NZ_CP018039.1\|WP_003814358.1\|239541_240285_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	5.58304e-45
NZ_CP018039.1\|WP_003814356.1\|240328_241372_-\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270320	cd13602, PBP2_TRAP_BpDctp6_7, Substrate-binding domain of a pyroglutamic acid binding DctP subfamily of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold. DctP6 and DctP7 groups of the TRAP transporters that involved in pyroglutamic acid transport. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.99378e-85
NZ_CP018039.1\|WP_010929707.1\|256377_257769_+\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP018039.1\|WP_010929708.1\|257785_258766_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	1.13912e-41
NZ_CP018039.1\|WP_010929704.1\|248569_249271_-\|DnaA-regulatory-inactivator-Hda	gnl\|CDD\|236347	PRK08903, PRK08903, DnaA regulatory inactivator Hda; Validated.	2.81236e-100
NZ_CP018039.1\|WP_010929703.1\|247874_248573_-\|HAD-IB-family-hydrolase	gnl\|CDD\|319796	cd02612, HAD_PGPPase, phosphatidylglycerol-phosphate phosphatase, similar to Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C. This family includes Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C, PgpC (previously named yfhB) which catalyzes the dephosphorylation of phosphatidylglycerol-phosphate (PGP) to phosphatidylglycerol (PG). This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.91431e-64
NZ_CP018039.1\|WP_003814332.1\|253592_254231_+\|membrane-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	1.10927e-69
NZ_CP018039.1\|WP_019247543.1\|254373_255759_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|182376	PRK10319, PRK10319, N-acetylmuramoyl-L-alanine amidase AmiA.	1.25625e-84
NZ_CP018039.1\|WP_003814351.1\|245055_246012_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	6.01101e-118
NZ_CP018039.1\|WP_003814321.1\|260955_262710_+\|gamma-glutamyltransferase	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	0
NZ_CP018039.1\|WP_003814339.1\|249523_250573_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP018039.1\|WP_003814363.1\|238109_238520_+\|4-carboxymuconolactone-decarboxylase	gnl\|CDD\|131478	TIGR02425, putative_gamma-carboxymuconolactone_decarboxylase, 4-carboxymuconolactone decarboxylase. Members of this family are 4-carboxymuconolactone decarboxylase, which catalyzes the third step in the catabolism of protocatechuate (and therefore the fourth step in the catabolism of para-hydroxybenzoate, of 3-hydroxybenzoate, of vanillate, etc.). Most members of this family are encoded within protocatechuate catabolism operons. This protein is sometimes found as a fusion protein with other enzymes of the pathway, as in Rhodococcus opacus, Streptomyces avermitilis, and Caulobacter crescentus. [Energy metabolism, Other].	1.36265e-47
NZ_CP018039.1\|WP_010929706.1\|255689_256226_-\|bifunctional-alanine-racemase/tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl\|CDD\|223873	COG0802, COG0802, Predicted ATPase or kinase [General function prediction only].	2.28113e-54
NZ_CP018039.1\|WP_003814337.1\|250678_251620_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	4.17279e-156
NZ_CP018039.1\|WP_010929702.1\|246518_247874_-\|polynucleotide-adenylyltransferase-PcnB	gnl\|CDD\|130997	TIGR01942, pcnB, poly(A) polymerase. This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).	4.58369e-147
NZ_CP018039.1\|WP_003814324.1\|258901_259885_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein-BugE	gnl\|CDD\|270295	cd13577, PBP2_BugE_Glu, Glutamate transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	4.35876e-158
NZ_CP018039.1\|WP_003814355.1\|241542_243645_+\|TRAP-transporter-large-permease-subunit	gnl\|CDD\|129868	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit. The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive force-dependent uptake of dicarboxylates into R. capsulatus. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	2.77055e-96

>NZ_CP018039.1|WP_003814339.1|249523_250573_+|phosphoribosylformylglycinamidine-cyclo-ligase
MTNQHSAPLTYRDAGVDIDAGDALVDRIKPLAARTMRPGVLAGIGGFGALFEVPKKFREPVLVSGTDGVGTKLRLAFDWNRHDTVGIDLVAMSVNDILVQGAEPLYFLDYFACGKLSVDTAAAVVGGIARGCELAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVDKSAIIDGKSIQPGDVVLGLASSGAHSNGYSLVRKILERAGARPDQDFHGQPLVDVVMAPTRIYVKQVLAALDRHGPAIKGLAHITGGGLLDNVPRILQPGMAAQLQRDGWEMPKLFQWLQQQGSVADAEMHRVFNCGIGMVLVVAADQADAVAATLREQGEIVNRIGEIVPQQDGMAQTVVV
>NZ_CP018039.1|WP_010929704.1|248569_249271_-|DnaA-regulatory-inactivator-Hda
MNRQLLLDVLPAPAPALNNYIAGPNGQALAAAHALTAGRAIYLWGPAGCGRTHLLRGLSARPEAIYIDAARAAQSLRELAEADSTAPMPRLVAVDDVHRMDDARQAGLFALYNRWRESAATGRAFALAVSGDRAPMSLPLREDLRTRLGWDLVFRLDPLSDADKLAALTAQAAERGLQLAPEVINWMLTHHERDIRKLAALLDALDRYSLATGRPITIPLLRAMLADPHSQAT
>NZ_CP018039.1|WP_010929703.1|247874_248573_-|HAD-IB-family-hydrolase
MTTRRLALFDLDHTLLPLDSDYQWADFLARTGRAGDPAEARRRNDDLMERYNRGELTAEQAAEFMLGLLAAHSPVELAAWHEEFMRDVIRPSLTVQAVDVVRGHLAAGDLCALVTATNSFVTAPIARAFGVQHLIATDPEYRDGRYTGRIEGTPSFREGKVVRVNQWLAGMGLALGDFAESYFYSDSVNDVPLLEAVTRPIAANPSPGLREIAQARGWQVIDLFDHLEDAKS
>NZ_CP018039.1|WP_010929702.1|246518_247874_-|polynucleotide-adenylyltransferase-PcnB
MITETIRKFVGRLFAPALRGPQRIGAERHGIDRRNVSRHAIKVCDVLRQHGYEAYIVGGAVRDLIVGLEPKDFDVATNATPEQIRPLFRRARIIGRRFQLVHVVFGQEIIETSTFRAPASDDQETDEHGRILRDNVFGSQEEDAARRDFTMNALYYDPHTEEVIDYHQGVQDLKKRQVRIIGDPVKRYREDPVRMLRAVRFAAKLNGSIDTATRQPIRTMASLIENVPASRLFDEMLKLLTCGHAMDCLRQLRNDGLHHGLLPLLDVVLEQPGGENFVELALERTDARVRAGKTISPSFLFAALLWQLVDVRWKQLRAQGEHNIPALVQAADSVLDEQTEKLAIQRRFSSDMREIWFMQPRFERRAGKTIYRMLEQPRFRAACDFLQLRAAAGEFDSVLAQWWMDLANGDDATRAEMIEETAHLPRETGDAPAQKRRRPRRRPSNRPREPQ
>NZ_CP018039.1|WP_010929701.1|246030_246522_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MNGSPASTLAYVGLGASLGDAAATLRSVLAELAAAPGILACKASRLYRTAPVEAQGPDFVNAVAALDTTLAPLDLLDLLQALEQRHGRERPYRNAPRTLDLDLLLYGEQAIDHPRLSVPHPRMHERAFVLAPLCELVPALRLAQGDCAALLAALEDQAIEPLR
>NZ_CP018039.1|WP_003814351.1|245055_246012_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKKRIWGTLLAAAMTVGSGAAHAGYPDKAVRIVVPFAAGGGVDALARPFAKELGDILGQSIVVENKPSNTGQIGATDVARAAADGYTLLLSSAAFATTPAFYPQVPYDPVKDFSPVMIMAAAPQVLVASNRFKAASLPDVLAQARQSDRINFALSASTGIQALATAMLAGQGGVTFMTIPYKGAGAAFMDLISGEVDLMIDNPASSLVHVRAGKLRVLATTGSKRMAILPDVPTVAETLPGFEARNWFVLAAPQGTPPAVIQKLNEASARALNTPAMRQMLERDGIDLVADSPAHAAAFLQDEIAKWGKVVKEGNLQP
>NZ_CP018039.1|WP_003814355.1|241542_243645_+|TRAP-transporter-large-permease-subunit
MSSIEMPAPVMPIEPAELAGASPYPLAIDQDFCLIRWMAAISRACGALATVALLLMALSMCYEIFSRYLFNAPTAWATEISGYLLVATVFFGLAAAQASNSHVQVELWIDRLSAPVRLRVELLCQWLALLFCVVLGWQMASFNVREYLNDTRDWGLLSTPQWMPELAVSVGMVVFCMSILVDIYRLSPPAQAWRRWLTPALLALLAAALVALGANAVPMAAGGRFDWGMALIVAALLACAWAWSGVRTLAHVVLVVGGCAVLYGLARGQSLGWVAFLLVASMMLLLFLGVRIGVALGLVGLFGVYFLLSRPQLSLLAERAWSSTNTFTLTAVPMFIFMGGLLLRSGITAGMFDALVRWFGRAPGGLAHASAGASAVFAAVSGSSLATAATLGKVACPDMIERGYSPRLTYGVAAAGATLGILIPPSIPMIIYGTTVGASVTHLFLAGMLPGLLLMACFMLGALVWALAVPGSAPVARAYTLREKLSASRGMVPFVAIIGAVLGSMYTGVATPTEAAAIGAVSAFVLCLVRRQLSWRALFEIAHDSAKVTALLLLIVVGAGIFSWVFDYLRLPREVVNLIQGADLSPALIVAAMVLAYLVLGMFVESIAMMLMTLPVTYPIAMSLGLDPIWFGVFLVLMIELGLITPPVGMVLFVLRSMNEKARFTDIIRGALPFVLIILLFLCLIYIYPQIVMWLPQQVK
>NZ_CP018039.1|WP_003814356.1|240328_241372_-|TRAP-transporter-substrate-binding-protein
MSQRFPLPRGFQAALAAAALCTASWSGAAAAQTYDLTMAVITSPGDGYSILTASVPERVAKATDGKVKVTVSDSLVPPAQIATAVREGRVDMSAALHTYLAADEPRMGIFNLPGLINNIQEYKQVCDAFWCEDTRKIWKDKWNAIVLAEGAWCTQQLFSKDPIHKVEDFKGKRLRVHNPQTAEVVNALGGKPVAMPTTEIFPALERGVIDGLFISTCVGGSLEFWRIAKNVQNWSLGPINGWAILANPDSWQKLPADVQKQVQGAMDALQQEAFGNYDTFVSNAQQEMMKKGVTFWVAPEEERAKLMQQQYIGPSYEAWNKRAKQVGFDGPAYLDRVRTTLGKSASN
>NZ_CP018039.1|WP_003814358.1|239541_240285_-|GntR-family-transcriptional-regulator
MPFPFCNTNRMTSPAAPEGEFKVQRVASVLRHSVTESIRNAILVGRFRPGERLPERELCEMTGVSRTLVREALRQLESEGLIVVIPHRGPVVERLSPEQARGIYQVREELEGLACQLFAEHATEPQLAALQEAFQALKRALTRGTPLEQIAAKNAFYQQLLDGAGNEALTTTLRLLNSRVMLLRSTSMQAPGRAKHSVAELSNLLQALVARDGKAARKAGSLHVRNAASVAIAILQDSLADAAATAE
>NZ_CP018039.1|WP_003814363.1|238109_238520_+|4-carboxymuconolactone-decarboxylase
MALRPEFQTEQFQKGLAVRRAVVGDAYVDKSLNSADDLTASLQKLVTEYCWGEVWTRPGLERKTRSFLNLAMLIALNRPNELRLHLRGAINNGVTKDEIVEVVLQAAIYCGVPAALDAMKAVREVVETMEKEGAFA
>NZ_CP018039.1|WP_003814337.1|250678_251620_-|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MTPRAIICLAGPTAAGKSASTLALAQRWPLEIINVDSATIYRGMDIGTAKPSAAERAQVPQHLLDIRDPAQSYSAAEFRADALRLIAEIHARGRIPLLAGGTMLYYKALREGLDDLPQADPALRAELEARAARLGWPALHAELALLDPATAARLSPNDSQRIQRALEICRLAGQPMSALLQGERRGDAPSPYRYVTLSLEPSERAALHARIAQRFDAMLAAGLVEEVRGLHARPDLHPGLPSVRCVGYRQMWSYLDGDIDLDTAREQGVAATRQLAKRQLTWLRAQPERVIIDCLAGDAVARTVDAMARALPD
>NZ_CP018039.1|WP_010929705.1|251616_253506_-|DNA-mismatch-repair-endonuclease-MutL
MSDRRPIATLPDLLISQIAAGEVIERPASVLKEILENAIDAGARAIEVRLEGGGIRRIAVTDDGSGIPPEELPLALTRHATSKIRSLDELESVASMGFRGEALASIASVADLTIISRTRGAEHAWQIDGGSLQVSPASGPPGTTIDVRQLFDRVPARRKFLRSEATEFGHCVDAMERIALAHPEVAFRLFHHDRAQRQWLPADHGQRIRDVLGAEFVGHVLPVLAAAGAIALMGMVTRPTAARARADRQYLYVNGRFVRDRTVSHALRSAYADVLHGDRQPAYVLYLDIDPGAVDVNVHPAKHEVRFRDSGAVHRFVSQVVGQTLAQTGGAEAVPAGVPDGAAPDTAYAGEPAAAAPGLAEPRAPYPAAYPSPGQSPYQGSPARPHTQVPFRLHGEPAGIPATDWQSLYRPLPGDAAPAATALRAAPATPLPTADEHPLGQALAQLHGIYILAQNSRGLVLVDMHAAHERVVYEQLKRALDDRALPRQDLLVPVVFHAAEKDVALVEEHETQLNELGFEMRPSGPASIAVRSVPALLARGDIESLARAVLRDLGAVGVSRLLTEQRNELLSTMACHGSVRANRRLTLEEMNALLRQMEITERADQCNHGRPTWVQWSVNDLDKLFLRGQ
>NZ_CP018039.1|WP_003814332.1|253592_254231_+|membrane-protein
MLDFFNMVLHIDQTLGIWVEQYGVWVYLVLFLIVFAETGLVVLPFLPGDSLLFIAGAFGATGHMDPVLTAALLIVAAISGNTVNYTIGRYIGPRVFSMNLRFLDRNALMRTHAFYEKHGGKTIVMSRFIPVIRTFAPFVAGVADMRLARFQLFNIGGALLWVISLVAAGYFFGNIPLVREHLNTIVLIGLGAAIVPVVIGALVRLLQVRRGQ
>NZ_CP018039.1|WP_019247543.1|254373_255759_-|N-acetylmuramoyl-L-alanine-amidase
MVERDCPPAHGALSPRAAARRRLISVAATLLVLPVVPRLAHAATILAVRTWPADEYTRVTLELDSELKAEHFTLENPHRLVVDIEGLSVNAALNDLVSKVRHDDPYIQGLRVAQNRPNVVRLVFDLKQSVAPQVFTLKPVADYQYRLVLDLYPKVAQDPLMAILNKQSGPDVDDPLARVLDEIARNQPAPDQPAAPLARGQEPAPALPAPPIKPLPAPGRSASRKRMLTIALDPGHGGEDPGAIGRSGLREKDVVLRIARRLKTLIDAQPYMRAYLTRDDDYFVPLHVRVQKARRVRADLFVSIHADAFIKPTANGSSVFALSERGASSTQARWLADKENAADLIGGVNLGSHDRQVAKVLLDLSTTAQINDSLKVGSAFLDEIKKINRLHKNRVEQAGFAVLKAPDIPSILVETAFISNPKEEALLRSAAHQEKLAQAMMTGIDRYFTANPPLARVGDVS
>NZ_CP018039.1|WP_010929706.1|255689_256226_-|bifunctional-alanine-racemase/tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MSAPPTTLCLHLPDEAATENLARQLAPLVDGRRGGQPGGQIHLQGDLGAGKTAFTRALLRECGIQGRIKSPSYALLESYKVSNLYFYHLDFYRFSDSREWLDAGFRDLLRDDAVVLIEWPERAAGLLPPPDLLISLAYADQGRDASLTAHTARGQTWLNAIVPPPTARSLPAPPPADA
>NZ_CP018039.1|WP_010929707.1|256377_257769_+|class-II-fumarate-hydratase
MKTRTEKDTFGPIEVPEQHLWGAQTQRSLHFFAISTEKMPVPLVAAMARLKRAAAKVNAELGELDPQVADAIMRAADEVIAGKWPDEFPLSVWQTGSGTQSNMNMNEVLANRASELLGGERGEGRKVHPNDHVNRGQSSNDTFPTAMHVAAAVEVEHRVLPALKALRGTLAAKSAAFYDIVKIGRTHLQDATPLTLGQEISGYVAQLDLAEQQIRATLAGLHQLAIGGTAVGTGLNAHPQFSAKVSAELAHDTGSAFVSAPNKFQALASHEALLFAHGALKTLAAGLMKIANDVRWLASGPRSGLGEISIPENEPGSSIMPGKVNPTQCEAVTMLAAQVMGNDVAINVGGASGNFELNVFKPLVIHNFLQSVRLLADGMVSFDKHCAAGIEPNRERITELVERSLMLVTALNPHIGYDKAAQIAKKAHKENLSLKEAALALGHLTEAQFAEWVVPGDMTNARR
>NZ_CP018039.1|WP_010929708.1|257785_258766_-|AEC-family-transporter
MSENSSLRRDAEAPLLSIFLPGSMSVALLVLPDFMLVALGWALRHKLGFSREFFAGTERMVYFVLFPALLFQSILRTPISAGHAMQLLQATAALMACGVALAWLAGPVLRPAPVALASAAQCGYRFNTYIGLALAASLAGGPGQTIMALIVGFAVPMANVAAVYGLARHSGNGLLRELARNPLLVSTLLSLACNLAGLSLPGPIDTVMARLGAAALALGIMCVGASLAWEGGKGHGRLIGWMLAVKLAAMPSAALGIAWALGLPALETRMLVLFSALPTASAAYVLAMRMGGDGRMVAVLISLGTLASAATIPLWLTAAAGLGAPN
>NZ_CP018039.1|WP_003814324.1|258901_259885_+|tripartite-tricarboxylate-transporter-substrate-binding-protein-BugE
MNKVRTLVQAIAVATGLVAAAGAQAADAYPSKAIRVIVPFAPGGSTDIIARLVTQRMSQELGQPMVVENKGGAGGAIGASEAARAEPDGYTLSIATVSTMAVNPACRPKDLPYDPIKDFQPVTNFANTANVVAVNPKFPAKDFKGFLEELKKNPGKYSYGSSGTCGVLHLMGESFKMATGTDIVHVPYKGSGPAVADAVGGQIELIFDNLPSSMPQIQAGKLRAMAIAWPTRIDAIKDVPTFADAGFPVLNQPVWYGLLAPKGTPMDVVNKLRDAAVVALKDPKVIKALDDQGSAPSGNTPEEFAKEIKEQYDWAQDVVKKQNIKLD
>NZ_CP018039.1|WP_010929709.1|259949_260849_-|LysR-family-transcriptional-regulator
MRLRHIEIFEAIRRTGSLTEAAAALHISQPAASKLLAHAEAQLGFKLFERVKGRLVATREAEILAPEVARLNQDLGSVRRLAASLRDRPHGHLRLGCAPALGLGLLPGVVRASRDAQPGITFDIHTHHSAELVQGLLAHELDLAITFDANNHPGLTRTSLGHTELVHLSRLPGAGTTRLQELGGETLIVLDARDASGSLLQMALDAQGLAPRVAIQVQTHYVACALAEAGCGDAVVDAITARAMLRPGMALRRLEPALRVPISVMTRSQDALSTLHHDFIERLRQACSVLQAQPAPQPE
>NZ_CP018039.1|WP_003814321.1|260955_262710_+|gamma-glutamyltransferase
MPLRTLLAALCAAAICQAPAWAREAPGVAREDVNPEIASARSERAQAHAQRYMIATANPLASEAGYRILRAGGSATDAIIAAQLVLNLVEPQSSGIGGGAFMVHYDRGAGELRVYDSRETAPAAARPDRFLREGKPLSYAESVNNGRAVGTPGLLRGLELAHRQHGKLPWQALFEPAIAMAEQGFAVSPRLHESIAGDKALAAQPAAARYFYGPDGQAWPVGHRLRNPEFAATLRSIAREGADAFYRGPIARDIVAAVRAHPTPGDLAEADLAGYRAVVREPVCGLYRGYRLCGAPPPSSGPLAVLQMLGELEQYPLARMRPGSVEAVHYFSEAGRLAFADRDFYVADPAFVDVPVRALLDPAYLRQRGALIRPDRSMKTALPGDPQGLLAERARDDAIEVPSTSHLVAVDAAGNVVSMTSTIEAAFGSKIFVRGFLLNNEMTDFSSSYRDPEGRLVANRVEPGKRPRSSMAPMIVFRAGKPVLALGSPGGSAIINYVAKTLVGVLDWKLDVQQAIALPNLGSRNKETELERGTALEALAPALRRMGHEVRITDFPSGIQGIVIGPHGLAGGADPRREGLALGD

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Crispr_ID: NZ_CP018039_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018039_2

432024-432117

Orphan

Consensus_repeat	Method
GTGCCTGTCCCCGCCGGGACAGGCAC	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP018039_2

>merge|NZ_CP018039|2|432024-432117|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCACCCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGCGTGCCTGTCCCCGCCGGGACAGGCAC

>NZ_CP018039|2|2|432024-432117|CRISPRCasFinder
GTGCCTGTCCCCGCCGGGACAGGCAC	CCGGGCCCAGGAAAACCCCCACGCTGCGCCCGCTGTGCGGGC
GTGCCTGTCCCCGCCGGGACAGGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018039.1\|WP_003814685.1\|440052_441024_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270234
NZ_CP018039.1\|WP_003814720.1\|419363_420422_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NZ_CP018039.1\|WP_003814730.1\|427133_427868_-\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235574
NZ_CP018039.1\|WP_033446199.1\|420551_421046_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP018039.1\|WP_003814728.1\|426544_426724_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377342
NZ_CP018039.1\|WP_003814694.1\|437024_437780_+\|TerC-family-protein	unknown	unknown	gnl\|CDD\|223930
NZ_CP018039.1\|WP_003814726.1\|425040_426354_-\|short-chain-fatty-acid-transporter	unknown	unknown	gnl\|CDD\|224942
NZ_CP018039.1\|WP_010929789.1\|436395_436914_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
NZ_CP018039.1\|WP_003820700.1\|432762_433107_-\|TIGR01244-family-phosphatase	unknown	unknown	gnl\|CDD\|225984
NZ_CP018039.1\|WP_010929577.1\|430312_431263_+\|IS481-like-element-IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018039.1\|WP_010929786.1\|423513_425025_+\|TAXI-family-TRAP-transporter-solute-binding-subunit	unknown	unknown	gnl\|CDD\|270238
NZ_CP018039.1\|WP_003814681.1\|441034_442012_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176106
NZ_CP018039.1\|WP_019247419.1\|442137_443310_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173841
NZ_CP018039.1\|WP_019247421.1\|431394_431793_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|234569
NZ_CP018039.1\|WP_003814701.1\|432203_432674_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP018039.1\|WP_010929791.1\|439200_439986_+\|crotonase/enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl\|CDD\|181723
NZ_CP018039.1\|WP_010929785.1\|422311_423517_+\|sodium/glutamate-symporter	unknown	unknown	gnl\|CDD\|129314
NZ_CP018039.1\|WP_010929788.1\|433206_434607_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP018039.1\|WP_022997984.1\|421138_422116_+\|IS481-like-element-IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018039.1\|WP_003814691.1\|437975_439208_+\|CoA-transferase	unknown	unknown	gnl\|CDD\|367110

Protein	Function_ID	Function_description	E-value
NZ_CP018039.1\|WP_003814685.1\|440052_441024_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	2.06741e-117
NZ_CP018039.1\|WP_003814720.1\|419363_420422_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	4.18053e-89
NZ_CP018039.1\|WP_003814730.1\|427133_427868_-\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|235574	PRK05711, PRK05711, DNA polymerase III subunit epsilon; Provisional.	2.40573e-142
NZ_CP018039.1\|WP_033446199.1\|420551_421046_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.34959e-07
NZ_CP018039.1\|WP_003814728.1\|426544_426724_-\|hypothetical-protein	gnl\|CDD\|377342	pfam04391, DUF533, Protein of unknown function (DUF533). Some family members may be secreted or integral membrane proteins.	0.00323203
NZ_CP018039.1\|WP_003814694.1\|437024_437780_+\|TerC-family-protein	gnl\|CDD\|223930	COG0861, TerC, Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism].	1.14565e-78
NZ_CP018039.1\|WP_003814726.1\|425040_426354_-\|short-chain-fatty-acid-transporter	gnl\|CDD\|224942	COG2031, AtoE, Short chain fatty acids transporter [Lipid metabolism].	6.57351e-166
NZ_CP018039.1\|WP_010929789.1\|436395_436914_-\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	1.12064e-44
NZ_CP018039.1\|WP_003820700.1\|432762_433107_-\|TIGR01244-family-phosphatase	gnl\|CDD\|225984	COG3453, COG3453, Uncharacterized protein conserved in bacteria [Function unknown].	3.40043e-35
NZ_CP018039.1\|WP_010929577.1\|430312_431263_+\|IS481-like-element-IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	9.02206e-23
NZ_CP018039.1\|WP_010929786.1\|423513_425025_+\|TAXI-family-TRAP-transporter-solute-binding-subunit	gnl\|CDD\|270238	cd13520, PBP2_TAXI_TRAP, Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold. This group includes Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family and closely related proteins. TRAP transporters are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an SBP (substrate-binding protein) of the DctP or TAXI families and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function. The substrate-binding domain of TAXI proteins belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and tworeceptor cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.13066e-82
NZ_CP018039.1\|WP_003814681.1\|441034_442012_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.33368e-60
NZ_CP018039.1\|WP_019247419.1\|442137_443310_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	4.27565e-82
NZ_CP018039.1\|WP_019247421.1\|431394_431793_-\|GTP-binding-protein	gnl\|CDD\|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	1.37761e-90
NZ_CP018039.1\|WP_003814701.1\|432203_432674_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.38587e-30
NZ_CP018039.1\|WP_010929791.1\|439200_439986_+\|crotonase/enoyl-CoA-hydratase-family-protein	gnl\|CDD\|181723	PRK09245, PRK09245, crotonase/enoyl-CoA hydratase family protein.	5.15941e-155
NZ_CP018039.1\|WP_010929785.1\|422311_423517_+\|sodium/glutamate-symporter	gnl\|CDD\|129314	TIGR00210, Sodium/glutamate_symport_carrier_protein, sodium--glutamate symport carrier (gltS). [Transport and binding proteins, Amino acids, peptides and amines].	1.2444e-106
NZ_CP018039.1\|WP_010929788.1\|433206_434607_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	3.43796e-109
NZ_CP018039.1\|WP_022997984.1\|421138_422116_+\|IS481-like-element-IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	9.0826e-23
NZ_CP018039.1\|WP_003814691.1\|437975_439208_+\|CoA-transferase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	8.36236e-118

>NZ_CP018039.1|WP_019247421.1|431394_431793_-|GTP-binding-protein
MTRRTSIERYRNIGISAHIDAGKATTTERILFYTGITHKLGEVHEGAATMDWMEQEQGRGITITSAATTAFWRGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYDSVGGVQEVATVMVVLPGQ
>NZ_CP018039.1|WP_010929577.1|430312_431263_+|IS481-like-element-IS481-family-transposase
MNTHKHARLTFLRRLEMVQQLIAHQVCVPEAARAYGVTAPTVRKWLGRFLAQGQAGLADASSRPTVSPRAIAPAKALAIVELRRKRLTQARIAQALGVSASTVSRVLARAGLSHLADLEPAEPVVRYEHQAPGDLLHIDIKKLGRIQRPGHRVTGNRRDTVEGAGWDFVFVAIDDHARVAFTDIHPDERFPSAVQFLKDAVAYYQRLGVTIQRLLTDNGSAFRSRAFAALCHELGIKHRFTRPYRPQTNGKAERFIQSALREWAYAHTYQNSQHRADAMKSWLHHYNWHRPHQGIGRAVPISRLNLDKYNLLTVHS
>NZ_CP018039.1|WP_003814730.1|427133_427868_-|DNA-polymerase-III-subunit-epsilon
MRQIIFDTETTGLDPAQGHRIVEIGCVEIVNRMVTGNNLHLYLNPDRDSDPEALAVHGLTTEFLADKPRFAEVAEQFLAFIADAELIAHNAAFDVKFFNAELQRIGRDPLNTHCENIVDSLLHARSLHPGKRNSLDALCDRYGISNAHRTLHGALLDSQLLAEVWLAMTRGQDALLIDVDDQGANANGALVLGKFDASVLTVLAASEAELAEHAAYLQALDKAVGGACAWRAIEPLPAESGQPG
>NZ_CP018039.1|WP_003814728.1|426544_426724_-|hypothetical-protein
MHPDTNTMLIIIAAAVALMIVGFGLRDRNLGLGLLGIGLIAALATIAYKAYITFNSFYY
>NZ_CP018039.1|WP_003814726.1|425040_426354_-|short-chain-fatty-acid-transporter
MFKLMSRSAVKMVERYLPDPYVFVVLLTLVAAGAAMIIEGQTPMAVVRWWGNGFWGLLTFAMQMLLVLVTGYMLASTPLVKRMLARLASLATSAGGAIILVSVVSLAASWINWGFGLVVGALFAKQIARQVRVDYRLLVASAYSGFIIWHGGLAGSIPLTIATEGHFSADKIGIIPTGDTIFAVFNLVIVVAMFILVPLVNRLMLPDEKESVYVDPARLEEASVPASDDDKRPAARLENSRLLAWLIAAGGLAYMFDYYVVRGAGLNLNVINFSFLILAILLHGTPRRLLASLDEAIKGGAGIVIQFPFYAGIMAIMMDSGLAATLSEWFVSIASAATLPFWTFISAGIVNIFIPSGGGQWAVQSPIVISAAQALGADMPRVAMAVAWGDAWTNMLQPFWALPVLAIAGLKAKDIMGYCIIQLLVTGVIISVGLSFF
>NZ_CP018039.1|WP_010929786.1|423513_425025_+|TAXI-family-TRAP-transporter-solute-binding-subunit
MTMFIRWLILSACLLLAACSRAPDTEILQRDVGQTLAATYGPDLFDIVALRRMGSATDSTAPPGQTRRVVYYDVVLGLKKDLTLGAWDQPGAAALVSLLGAGPRSISGVKSSGNAAGDQIVAHASAIYQRDAEQWVHVAPASFTATEAPSLDTGAPPPVTRQLLQTLEQITRSVPYSASSTAQHVVQQELERSVARINGRLARLQKGYPLATGPDKGEYLAFGQALAAIGRNEQVRVIPLITGGSADNMAMLRSGAAVAALSQADIAQLAYEGKGPFESQGPFSGLRALGSLYPELVHIVVRQGDGIATVGALRGKKIALGPSGSAVRTTLETVLAAHGLQPGRDYAVIDTPAAAALPQLSEGRVDAVAQVIGTPAAPLRAALTQARLALLPLDRAAIDKLVQADPTLMALDIPANTYPSQAAAIPTVGMAALLVTTADLTRDEAAHMVDVVYRAGQDLLAAGSAQGAQVSAANAGRGLSIPLHDGAVEAFEKLGAPPLPEGR
>NZ_CP018039.1|WP_010929785.1|422311_423517_+|sodium/glutamate-symporter
MISLTPVQSLLACCLVLVAGRILTTRIGVLSRYSIPDPIVGGLLFAVLATALDTWGGIQISLETNIKPTLLLIFFGCIGLTADLKLLARGGPRLIAFLLALIPFLVLQNAVGLGLAWLLDMHPLMGLIGGTITLVGGHGTGAAYAARFADINNIQDVMALAMTAATIGLVLGGIIGGPVAEWLIRRHKLDPRMAGKDANQVLPEVETTAEAPTATSFITSLTAVFVTVVVGTYLAGLVEDAPISLPNFLWCLATGAIIRNFGGYVGIRLDDRVSEIIGSISLSLFLGLTMMTLDLSSVVRLAGPLALMLVAQALVCALYAGWAVFRMLKRDYEAAVMAAAFCGFAMGATATAIANMQALTRRHGPAPESFIVVPVTGAFLVDILNVIVLTSLIALPFVGGM
>NZ_CP018039.1|WP_022997984.1|421138_422116_+|IS481-like-element-IS481-family-transposase
MNTHKHARLTFLRRLEMVQQLIAHQVCVPEAARAYGVTAPTVRKWLGRFLAQGQAGLADASSRPTVSPRAIAPAKALAIVELRRKRLTQARIAQALGVSASTVSRVLARAGLSHLADLEPAEPVVRYEHQAPGDLLHIDIKKLGRIQRPGHRVTGNRRDTVEGAGWDFVFVAIDDHARVAFTDIHPDERFPSAVQFLKDAVAYYQRLGVTIQRLLTDNGSAFRSRAFAALCHELGIKHRFTRPYRPQTNGKAERFIQSALREWAYAHTYQNSQHRADAMKSWLHHYNWHRPHQGIGRAVPISRLNLDEYNLLTVHSYMVRADLAG
>NZ_CP018039.1|WP_033446199.1|420551_421046_+|GNAT-family-N-acetyltransferase
MPQSYIVRTMRPADVEAVLRVQAAVYPASLLESAALFQNRIEIAPATCQVALDGQDLIGYLIAYPWDAGLPPALDRSLERLPGAADTWFVHDCAVLPAAQGGGVAAALLAGGRAQARRLGLRRASLVALAQAVGYWLRHGYQPLADSDALRAKLAGYGDGARYM
>NZ_CP018039.1|WP_003814720.1|419363_420422_-|glycosyltransferase-family-2-protein
MFMYTEFRSQLLAGAGTSAAGQSARMAVLAGDGATGVQVSCVVPGLNEAANLRVLVPALRACLEQWCASWEIIVVDDGSTDDTAELMAQWSAVEGIRYVQLSRNFGKEAALTAGLEAADGDAVICLDADMQHPPELIGDMLAAWRNGADMVYAVRRQRDDEPWFKRVGARAFYRLLSTARGVEVPPHAGDFRLMDRRVVEALVALPERTRFMKGLYAWVGFKSQAVPYTPQARRHGASHFSAWKLFRLACDGLTAFTTWPLRLVSLIGVLFALLSLSYGGYLVADYLISGNAVSGWTTIVTALLFFAGINLISLGVVGEYVARIFDEVKGRPLFIARQRRGRAKRAAKARSQ
>NZ_CP018039.1|WP_003814701.1|432203_432674_-|universal-stress-protein
MFKKILIPTDGSPLSAQAANAGICFARSTGAEVVALHVTQPFAATIGFDGMAAAYAITDEDYEKASAEQAEKYLKLILDRAETAGVKAESRAVSNFNVADGIVQAAGEAGCDLIFIGSHGRSGLSRLLLGSVTAKVLSLAHTAVLVYRVKEDKDKK
>NZ_CP018039.1|WP_003820700.1|432762_433107_-|TIGR01244-family-phosphatase
MSAAIKPLTENFAVAPQLGPADMADVAAAGYKSVIINRPDFEGGPDQPTAADVSQAAQALGLQVEYQPVVGSAMTAADVARFAELLRTMPGPVLAYCRTGTRCTNLFAAAQQLG
>NZ_CP018039.1|WP_010929788.1|433206_434607_-|PLP-dependent-aminotransferase-family-protein
MRQADATLVTQLADDLARRIDEHGLRPGTRLPSIRRMAEQSGVSRFTVVEAYDRLVARGLVQSRHGAGFFVRARSASLTALASARVPQAAPETPVRVDVSWLLRNMFRETAAGMPGGAGLLPPEWLDPDMVAAAVRAVGRTVRGNLVSYGSPQGYAPLRQQLASMLQADGVPAHPERNLLTTNGVTHGLDIVARHLIKPGDTVLVEDPAWFVIFGRLAAFGARPVGVPRGPDGPDLAMLDRLAAEHKPRLYIINGAVHNPIGHTLSAGAAYDILRLAERHDFMVVEDDTYADLHPGGAMKLAALDRLERVILVGGFSKMLAASLRVGYIAAGAETLQRLTDLKMLAGLTSPELGERVVHRVLVEGQYQRHIERVRARVNEARLRSIQALQQLGLSVPHEPHAGMFVWADCGRDSEPVARNAAERGMLLAPGTLFSPSGAPSTMLRFSVAMVDTPGIWQSIAAVMAQ
>NZ_CP018039.1|WP_010929789.1|436395_436914_-|MgtC/SapB-family-protein
MDTVWMEIWTTVRNEFADIPDVAEATRIVLRLGMAVALGGLLGYERERSGKAAGLRTHMLVALGAALFVLVPLQGGMEVGDLSRVLQGVIAGIGFLGAGVIIKLGNEGEIRGLTTSAGIWLTAAIGVAAGMGREATALASTLIALFVLAALRRLEKRIAARDDKRVVAQPPP
>NZ_CP018039.1|WP_003814694.1|437024_437780_+|TerC-family-protein
MDYLVSLAQQPAAWAALATLIAMEVVLGIDNLIFISILTNKLPPQHQTKARRIGIGMALILRLALLGTVAFIVQLTQPVFELFGHGFSWRDVILVAGGLFLVWKATKEIHHHVDPNPGDDMFGGKAATLGFAAAVAQILMLDLVFSIDSIITAVGMTEHIPIMFVAVIVAVAVMLLAAEPLARFIERNPTVVMLALAFLMMIGMTLIAEGFGAHVPKGYIYAAMAFSALVEGLNMMARRAREGRGAGAAGG
>NZ_CP018039.1|WP_003814691.1|437975_439208_+|CoA-transferase
MSGPLEGVRILDVTTVLMGPYATQILGDLGADVIKVEPPAGDNVRGIGPGRHADMGGIFLHANRSKRSIALDLKNPAGREALLKVAATCDVLVYNVRPQAMARLGLSYAEVAQANPSILYVGMYGYDQRGPYAARAAYDDLIQGAVGIPSLSVEAGSDIPRYAPSAMVDRIVGISAANAVTAGLYHRARTGQGQAIDVPMFETMAHLILGDHMMGQTFEPPLGPPGYPRILNADRRPYATRNGHICVLLYADKHWKAFFELIGQPGRDAADPRFRDIGTRTQHIHAIYRLVSDAIASRTTEEWLAAFEAADIPAMPVHTMASLLRDPHLEAIGFFGMVDHPSEGAVRMMAVPSRWSGTPPQPRGHAPRLGEHSVDVLKEAGYDDEAIAALVRNGAAIAAARQLPEGTDHD
>NZ_CP018039.1|WP_010929791.1|439200_439986_+|crotonase/enoyl-CoA-hydratase-family-protein
MTDFLRHERHGGVLLLTMDRERTRNALSDADAVEALVQACARIGADLSVRAVVLTGSHGVFSSGGNLKTLSDTVGAGLGEPVHSLQAYRSGIQRIPLALYNLEVPTIAAVNGPAIGAGCDLACMCDIRLAARQASFAESFVKLGLTPGDGGAWLLPRIVGMSRACELAFTGRSIDAARARELGLVSEVFDADALLPAALALAQEIAQHSGHALRLTKRLLREGQHTRLDTLLELSAGFQALAHHTQEHAGALDAHLSRKRG
>NZ_CP018039.1|WP_003814685.1|440052_441024_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MHSRTLALALLSVAALAQGGSARAASDYPAHPVKIIVSLPPGSGADTTARFLSKHLAERFKQPFVVENRPGGNSFIAAQAVATAPPDGYTLFVASNSPMTTNAAVFKNLPYDAVKDFAPVAPIARFPMALVVPANSPYRSVADLVAAARAAPGQLNFASGTATYQVVLELFHEQNGIKATHVPYKGTSAALADVAGGVVQYSVADVSAALPLIRGGKLRPLAVTSTRRIKDLPDVPTMQESGNKGFEAYAWTAAFFPAKVDPAIVARVSDAVQALVRSQEGKAFMEQLGGEPFVGGPDTLAAFQRDELASMRRIAKLANIQQE
>NZ_CP018039.1|WP_003814681.1|441034_442012_-|LysR-family-transcriptional-regulator
MWTGQYIVHIASPAHHWRRAVELRQLKQLLVLSETLNFHRAAERLHMAQPPLSTAIKKLEQELGVQLFERLPAGLQPTPAAEVVLRYARATLFYADEIQRAAQEGASGKQGMLKVGFVGSSIYSLMPQLLSAFRKDYPRVDLVIEESTTVDLLRRLDAHTLDVALVRFPVLEPSTARITLLQADHLMLAVPAGSRYAQRDDVALDELADEPFIGYSRTHVPGMHALIMYAFQQYGVVPHIAQEAIQVQTILSLVESGLGLAIVPKVACRQAGSGVRLVNVPQLAETIKVGIALAVHPDNATPTTANFVDMACRLMQTEPAAGQAR
>NZ_CP018039.1|WP_019247419.1|442137_443310_+|acyl-CoA-dehydrogenase
MGAILGTIIEALQLAAIPAHDEALRPAVRAFLDEALREMPADRRARSWMGHDAEFSRALARQGWLGLTLPVEYGGAGRSNFARFVLSEELLAVGAPVSAHWVADRQTAPLILRFGSPAQRAFYLPRIIRGEAFFAIGMSEPDTGSDLASVRTRATPVADGWLLNGRKIWTTNAHRSHYMCALVRTSGAPEDRHRGLSQMIFDLALPGIEIRPIRDIAGDAHFCEVLFDNVLLPHDALVGEEGSGWRQVMAELALERSGPERIYSSMVLLDGWLAHLRCDAAPQRAQVCLAGRLAARLAVLRSMSLAVSQRLEQGADASLAAVLVKDLGTEFEQAVPELIGQALHASPQPAPDDVLMRTLAYLTLINPTFSLRGGTRHILRGIIARELGLR

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Crispr_ID: NZ_CP018039_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018039_3

996336-996430

Orphan

Consensus_repeat	Method
TAAAAGGGCACCCGCAAGGGTGTCCTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018039_3

>merge|NZ_CP018039|3|996336-996430|CRISPRCasFinder
TAAAAGGGCACCCGCAAGGGTGTCCTTTTATTGCGAAAAGATATCTGGAAGAAAGCCTTTTCAGAGTAAAAGGGCACCCGCAAGGGTGCCTTTTT

>NZ_CP018039|3|3|996336-996430|CRISPRCasFinder
TAAAAGGGCACCCGCAAGGGTGTCCTTTT	ATTGCGAAAAGATATCTGGAAGAAAGCCTTTTCAGAG
TAAAAGGGCACCCGCAAGGGTGCCTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018039.1\|WP_014905652.1\|994710_995583_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|274527
NZ_CP018039.1\|WP_010930112.1\|988636_989701_+\|sulfate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213263
NZ_CP018039.1\|WP_005012067.1\|997300_998251_-\|IS481-like-element-IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018039.1\|WP_010926548.1\|1002067_1002640_-\|chorismate-lyase	unknown	unknown	gnl\|CDD\|225703
NZ_CP018039.1\|WP_029443805.1\|1003482_1004400_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP018039.1\|WP_010930118.1\|998355_999405_+\|NADP(H)-dependent-aldo-keto-reductase	unknown	unknown	gnl\|CDD\|381320
NZ_CP018039.1\|WP_023852693.1\|992894_994169_+\|PA0069-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|275263
NZ_CP018039.1\|WP_003821527.1\|983025_984852_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173842
NZ_CP018039.1\|WP_003821528.1\|985765_986800_+\|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224529
NZ_CP018039.1\|WP_010930111.1\|981852_982782_+\|electron-transfer-flavoprotein-subunit-alpha	unknown	unknown	gnl\|CDD\|224936
NZ_CP018039.1\|WP_003813314.1\|996479_997205_+\|CoA-pyrophosphatase	unknown	unknown	gnl\|CDD\|239518
NZ_CP018039.1\|WP_010929632.1\|999542_1000559_-\|IS110-like-element-IS1663-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP018039.1\|WP_010930119.1\|1002699_1003431_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP018039.1\|WP_010930113.1\|990498_991407_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP018039.1\|WP_010930123.1\|1009835_1010087_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP018039.1\|WP_010930121.1\|1005207_1008387_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|273335
NZ_CP018039.1\|WP_023852686.1\|994322_994703_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018039.1\|WP_003813333.1\|984934_985576_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|239314
NZ_CP018039.1\|WP_003813315.1\|995888_996269_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_CP018039.1\|WP_014486063.1\|1008383_1009766_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|273830

Protein	Function_ID	Function_description	E-value
NZ_CP018039.1\|WP_014905652.1\|994710_995583_-\|EamA-family-transporter	gnl\|CDD\|274527	TIGR03340, phn_DUF6, phosphonate utilization associated putative membrane protein. This family of hydrophobic proteins has some homology to families of integral membrane proteins such as (pfam00892) and may be a permease. It occurs in the vicinity of various types of operons for the catabolism of phosphonates in Vibrio, Pseudomonas, Polaromonas and Thiomicrospira.	3.74356e-26
NZ_CP018039.1\|WP_010930112.1\|988636_989701_+\|sulfate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213263	cd03296, ABC_CysA_sulfate_importer, ATP-binding cassette domain of the sulfate transporter. Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	3.07125e-165
NZ_CP018039.1\|WP_010930113.1\|990498_991407_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP018039.1\|WP_010926548.1\|1002067_1002640_-\|chorismate-lyase	gnl\|CDD\|225703	COG3161, UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) [Coenzyme metabolism].	1.05194e-17
NZ_CP018039.1\|WP_029443805.1\|1003482_1004400_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.56316e-67
NZ_CP018039.1\|WP_010930118.1\|998355_999405_+\|NADP(H)-dependent-aldo-keto-reductase	gnl\|CDD\|381320	cd19094, AKR_Tas-like, Escherichia coli Tas protein and similar proteins. Escherichia coli Tas protein is the prototype of this family. It is an NADP(H)-dependent aldo-keto reductase that catalyzes the reversible reduction of ketones to the respective alcohols using NADP(H) as a hydride donor.	0
NZ_CP018039.1\|WP_023852693.1\|992894_994169_+\|PA0069-family-radical-SAM-protein	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	4.71758e-24
NZ_CP018039.1\|WP_003821527.1\|983025_984852_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	6.94362e-153
NZ_CP018039.1\|WP_003821528.1\|985765_986800_+\|sulfate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224529	COG1613, Sbp, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	0
NZ_CP018039.1\|WP_010930111.1\|981852_982782_+\|electron-transfer-flavoprotein-subunit-alpha	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	1.05379e-120
NZ_CP018039.1\|WP_003813314.1\|996479_997205_+\|CoA-pyrophosphatase	gnl\|CDD\|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	5.50907e-72
NZ_CP018039.1\|WP_010929632.1\|999542_1000559_-\|IS110-like-element-IS1663-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.74666e-23
NZ_CP018039.1\|WP_010930119.1\|1002699_1003431_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	7.73356e-72
NZ_CP018039.1\|WP_005012067.1\|997300_998251_-\|IS481-like-element-IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	8.66858e-23
NZ_CP018039.1\|WP_010930121.1\|1005207_1008387_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NZ_CP018039.1\|WP_010930123.1\|1009835_1010087_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	2.42408e-12
NZ_CP018039.1\|WP_003813333.1\|984934_985576_+\|peroxiredoxin	gnl\|CDD\|239314	cd03016, PRX_1cys, Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by reducing and detoxifying hydrogen peroxide, peroxynitrite, and organic hydroperoxides. As with all other PRXs, a cysteine sulfenic acid intermediate is formed upon reaction of 1-cys PRX with its substrates. Having no resolving cysteine, the oxidized enzyme is resolved by an external small-molecule or protein reductant such as thioredoxin or glutaredoxin. Similar to typical 2-cys PRX, 1-cys PRX forms a functional dimeric unit with a B-type interface, as well as a decameric structure which is stabilized in the reduced form of the enzyme. Other oligomeric forms, tetramers and hexamers, have also been reported. Mammalian 1-cys PRX is localized cellularly in the cytosol and is expressed at high levels in brain, eye, testes and lung. The seed-specific plant 1-cys PRXs protect tissues from reactive oxygen species during desiccation and are also called rehydrins.	3.35179e-132
NZ_CP018039.1\|WP_003813315.1\|995888_996269_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	1.34063e-62
NZ_CP018039.1\|WP_014486063.1\|1008383_1009766_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|273830	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. Members of this model comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined. [Cellular processes, Detoxification, Transport and binding proteins, Porins].	9.9815e-102

>NZ_CP018039.1|WP_003813315.1|995888_996269_+|50S-ribosomal-protein-L19
MNLIAILEQEEIARLTGGNAVTEFAPGDTVVVSVNVVEGTRKRVQAFEGVVIAKRNRGLNSSFIVRKISSGEAVERTFQLYSPQIAGIEVKRRGDVRRAKLYYLRSRSGKSARIKEKLVLKKAKSA
>NZ_CP018039.1|WP_014905652.1|994710_995583_-|EamA-family-transporter
MSYTSLILVVLAAMAHAAWNLLAKRAAMVGPMFVFAYGLAATILYAPWVIWVLAHDGMVWSWPVVLCILASSMLHLGYSLCLQRGYQVADLSVVYPIARGTGPLLSTMGAFTLLSEPATTTGIAGMLCVVGGVLLIATQGRLGMFRQAQAWIGVRWGVVIGLFIAAYTVVDAYGVKILLIMPVLFDWFTCATRTLMMTPHVLRRRAQYWPAMRGYWHLAIAVGVLSPLGYILVLYALRNGAPLSLVAPAREMSMMLGTLAGMFLLREKVGIGRLAGCLAILAGVVLLGSS
>NZ_CP018039.1|WP_023852686.1|994322_994703_+|hypothetical-protein
MTIATTLDAATSLPTAVPGRTLGALRRLARAWAGAAVPQRKWPFPPTPPGQAQPCTPCTDSQPRSVQAVQPAQARALHAQAELSGAATQAATQVLSTKAKIIDVLLVAVWGAMIPALMWLGAAGGF
>NZ_CP018039.1|WP_023852693.1|992894_994169_+|PA0069-family-radical-SAM-protein
MASTEHSFSAGFGSPAAAPAALRGRGAVTNVPHRFQQADRVRVDDGWANPDYTAGSDAAALPSVAEALGQGGRRAIPIAVEGADASPNTCAQAPAPRTIVQAEEARKMLSRNDSPDIPFDVAANPYRGCEHGCVYCYARPTHAYLGYSPGLDFETRLVAKANAVAALRAELARPGYRASPINIGSATDAYQPIERTWRLTRGMLELLLQTRHPLTVVTKNALVERDLDLLQDLARQKLVTVFVSITTLDAAMARTLEPRASAPYRRLQTVRTLAQAGVPVGVLVAPVIPFINDESLEHILQEASAAGACYASYTVLRLPWEVKEVFETWLQAHFPDRAQRVLHRIEDLRNGRRNDTAFGSRMRGTGIWADLLRQRFALATRKLDLNRHRPELDTHRFVPPLEPGLPPARGRREARAQPGQLALF
>NZ_CP018039.1|WP_010930113.1|990498_991407_+|sulfate-adenylyltransferase-subunit-CysD
MSAVMTRSHLDWLESEAIFILREVAAECARPALLFSGGKDSVVLLRLAEKAFRPGRFPFPLLHIDTGHNYDEVISFRDARAAELGETLLVRSVEDSIARGSVALRRETDSRNAAQAVTLLEAIEELGLDACIGGARRDEEKARAKERIFSFRDEFGQWDPKAQRPELWNLFNTRVHRGENMWVFPISNWTELDVWQYIQRERLALPSIYYSHTREVVRRKGLLVPVTRLTPPAEGETVEQLAVRFRTVGDISCTCPVASDAADPAAIIAETAVTDITERGATRMDDQTSEASMERRKREGYF
>NZ_CP018039.1|WP_010930112.1|988636_989701_+|sulfate-ABC-transporter-ATP-binding-protein
MSIEVRGLSKRFGAFRALDEVSLHIETGELVALLGPSGCGKTTLLRIIAGLESADAGSVLFAGEDATEVDVRQRQVGFVFQHYALFKHMTVFENVAFGLRVRHRSQRPSEARIRAKVLDLLGLVQLDWLADRYPAQLSGGQRQRIALARALAVEPRVLLLDEPFGALDAKVRKELRRWLRRLHDELHVASVFVTHDQEEALEVTDRVVLMNAGRIEQVGSPREVWERPATPFVYGFLGDVNQLHGHATRGVWRLGEVALPAPDLPEADNQRAIAYVRPHDIDLARAGTAAPGIPVRLNHVYLAGPSAYLELARQDDQAIIEAQVPEPLFRSLGLKEGEALLAQPRRARVFAVQP
>NZ_CP018039.1|WP_003821528.1|985765_986800_+|sulfate-ABC-transporter-substrate-binding-protein
MPRNTAGIRGAIVALATVFSLGLPWAVQAQDKQTLLNVSYDPTRELYRAVDEAFIKEYQARAGVDLTVRQSHGGSGRQARSVIDGLDADVVTLALAYDIDAIADRGLLPQDWQKRLPRNSSPYTSTIVFLVRKGNPRQIHDWDDLVKDGVQVITPNPKTSGGARWNYLAAWAYALARNEGSEAKAREFVGQLLSHVPVLDTGARGSTTTFVERGVGDVLLAWENEAFLAREELGPDKFDIVVPSLSILAEPPVAVVDKVVDRKGTRAAAQAYLEYLYTPAAQEIIARNFYRPTDAGVAAKYASRFPKLKLVTIDDPIFGGWRKAQKDHFSDGGTFDQVYQPQRK
>NZ_CP018039.1|WP_003813333.1|984934_985576_+|peroxiredoxin
MGQLRLGDTAPDFEQKSSIGPLRLYDYLGDSWGVLFSHPADFTPVCTTELGYTAKLAGEFAKRNVKVLALSVDPVDSHTKWIDDINDTQSTTVNFPILADDDRKVSELYDMIHPNANATLTVRSVFVIDPAKKVRLTITYPASTGRNFDEILRVIDSLQLTDSHSVATPVNWKDGEDVIIVPSLKDEAVIKEKFPKGYKALRPYLRITPQPNK
>NZ_CP018039.1|WP_003821527.1|983025_984852_+|acyl-CoA-dehydrogenase
MTYATPLQDFRFALNELAGLEEILKLPGFEEVTPDLVDAILEENARFVQQAIAPLNVAGDTKPPVWNDGQVTTTPGFSQGFADYTAGGWQGLQHPQKWGGQGLPKVVAAPAGENIQAASLAFSLCPMLTDGVIEALLTVGSEAQRQTYVPKLIGGQWTGTMNLTEPQAGSDLAQVATRAVRQDDGSYRLSGQKIFITYGEHDLAENIIHLVLARTPDAPAGVKGISLFIVPKYLVNEDGSRGKRNDVWCASLEHKLGIHGSPTAVLLYGAGKGEVGEGAVGYLVGEANRGLEYMFIMMNAARYSVGQQGIGVSERAYQHAQAYARERVQGRAIEGSAAPVTIAHHPDVQRMLLTMRALTEAARAVSYVAAAAHDKGTHHPDAEVRARNRAFYEYLVPIVKGFSTESAVEVASLGIQVHGGMGFIEETGAAQHYRDARILPIYEGTTAIQANDLVGRKTLRDGGATAHASIAAMRDTLKAVAAEAQRADTADHTALRVLRDNFDQAIQSYEGAVEFILAHAASNVRAVYSSSVPYLMLAGVVHGGWQMARAALACRRHLAAGSGDAFHRHKLGTALFYGAHILPRALALAAAVRAGDVADSCGSMADIA
>NZ_CP018039.1|WP_010930111.1|981852_982782_+|electron-transfer-flavoprotein-subunit-alpha
MTTLVIAEHDNAQLKGATLNTIAAASRLGGEVHVLVAGSGAQAVAEQAAQAARVSKVLLADAPQLAEGLAENLAAQVLAVAGGYSHILFAATASGKNVAPRVAAKLDVAQISDIIGVESADTFQRPIYAGNAIATVQSGDAVKVITVRTTGFDAVAAQGGSAAVEALDAVADSGLSRFVGREVAKSDRPELAGARVVVSGGRGLGSAENFKILDPLADKLGAALGASRAAVDAGYAPNDWQVGQTGKIVAPQLYVAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFGVADYGLVGDLFQVVPELTGAL
>NZ_CP018039.1|WP_003813314.1|996479_997205_+|CoA-pyrophosphatase
MSDSAPSRPRRTPVRPLFDPMAQPWETANQGLARVDERLLTPPELRSSLRPADHWRLDPLCAAEPRAPGREGSLVAAAVLIPLVMRADGVRVMLTQRAAHLHDHAGQVSFPGGRIEVSDATPVAAALREAQEETGLPVQQVEVLGSMPQYFTATGFAITPVVSLVQPDFELAPDAFEVAEVFEVPLSFLMDPANHRLYRAALPDGYVRQYYAMPWQRYFIWGATAGMLRNLYQTVREALPG
>NZ_CP018039.1|WP_005012067.1|997300_998251_-|IS481-like-element-IS481-family-transposase
MNTHKHARLTFLRRLEMVQQLIAHQVCVPEAARAYGVTAPTVRKWLGRFLAQGQAGLADASSRPTVSPRAIAPAKALAIVELRRKRLTQARIAQALGVSASTVSRVLARAGLSHLADLEPAEPVVRYEHQAPGDLLHIDIKKLGRIQRPGHRVTGNRRDTVEGAGWDFVFVAIDDHARVAFTDIHPDERFPSAVQFLKDAVAYYQRLGVTIQRLLTDNGSAFRSRAFAALCHELGIKHRFTRPYRPQTNGKAERFIQSALREWAYAHTYQNSQHRADAMKSWLHHYNWHRPHQGIGRAVPISRLNLDEYNLLTVHS
>NZ_CP018039.1|WP_010930118.1|998355_999405_+|NADP(H)-dependent-aldo-keto-reductase
MKYRKLGHTDLDVSLIGLGTMTWGEQNTEAQAHEQLDYALAHGINLVDAAEMYPVPPKPETQGRTESCIGSWLARTGRRHEVVLASKAAGPVRDAKRPSHIRDGKTFLDRKNLTQALDASLKRLQTDYLDLYQLHWPDRTTNTFGKLAYPWVDDAHTVPIEETLEVLQDFVRAGKVRHVGLSNETPWGVARFLQAAEKHGLPKVATIQNPYNLLNRIFEIGLAEFSHREGVGLLAYSPLAMGILSGKYLDGARPEGSRLALFTRFTRYSNPQAEAAARDYVMLARDHGLAPAQMALAWVNQRPFVSSNLMGATTLAQLKENIESVEVTLSDEVLQGIEAIHARQPNPAP
>NZ_CP018039.1|WP_010929632.1|999542_1000559_-|IS110-like-element-IS1663-family-transposase
MADSSLLSAGGQVHVFIGIDVSKAKLDCTLLTAEADKCKTKVVVNTAAGVQALLAWCAKHGAQPAQLHAILEPTGLYHEQAATALPQVRVSLVNPAQARDFAKALALRSKNDALDSYVLARYGQTLSPALWHPAPLHARQLRALLTRREALSKDLLRELNRKEKSQFSPSAPLVDGSIDKAIAFLREQIKQIERAIDQHIDNHPDLKQDCELLNSIPAIGPQAGNAILAVMHNRHIDSAQSLAAYLGVVPVQRQSGSSLNSCARLSKAGPSQVRATLYMAALVGTRHNPHIRALYQRLLKAGKSKKAALGAAMRKLVHLCFGVLKNRIPYQPNYAMNG
>NZ_CP018039.1|WP_010926548.1|1002067_1002640_-|chorismate-lyase
MTTPIPLARGWLPAAPSTLDPLRKYWLFRPGALTAGLRQLGHVRLRVLAEYPTGAPRDEADGMRIAAQSPVWVREVLMSIDGVDSVVARSLTPLRASHGVWQGMRRLLTRPLADMLYHDPGIHRSVFVCRRLAAGVPFHATAIARAPAGGPEPALWARRSAFWRAGQPLLVAECFLPAFWSLARAPVAPR
>NZ_CP018039.1|WP_010930119.1|1002699_1003431_+|rRNA-pseudouridine-synthase
MEKVRISKLMSERGLCSRREADSYIERGWVRVDGVVVSELGARALPDQVITLERAAAARQTARVTILLHKPVGYVSGQAEKGYTPAVALIDARSRYAGDRAPQRFERGQLQGLAVAGRLDIDSQGLLVLTQDGRIAKKLIGEDSEVDKEYLVRVQGRLSEAGLALLNHGLSLDGKPLRPAQVRWQNADQLRFVLREGKKRQIRRMCELVGLRVVGLKRVRIGRVSLGDLPAGQWRYLRADERF
>NZ_CP018039.1|WP_029443805.1|1003482_1004400_-|LysR-family-transcriptional-regulator
MELFVEVARTLSFGRAAENLAIPKSTLSRQVAELERSVGLRLLSRTTRRVELTEAGQLYFERCQRIVAEARIAHEELQNLVETPSGPLRVNMPADFGTDFLSEAFTEFSRRYPEVTFYLDLASPEHAERVFQTCDVSIEIGDLPDSTHIARLLGVLPAHLYASPDYLARHGEPQHPDDLPRHECIQFRAGTGRVTRWPLNSGERHVEITPGNRFSVNSVSMVRNLATLGAGIAILAPMGNVREDIESGRLKRILPDWLAGPFPVYAVTDTRMLPAKTRIFVEFLMERLSNKTLAGQNNPAFLNLR
>NZ_CP018039.1|WP_010930121.1|1005207_1008387_+|efflux-RND-transporter-permease-subunit
MAKFFIDRPVFAWVIAIVLMMAGALSILSLPVAQYPNIAPPAISINVTYPGASAQTVQDTVVQVIEQQMNGIDNLQYISSESNSDGSMSITLTFSQGTNPDTAQVQVQNKLAVAQPLLPLEVQQQGIRVTKATKNFLIVAGFVSTDGTMDKSDLADYVASYIQDPISRTPGVGNFQLFGAPYAMRIWISPEKLVNFGLTASDVTTAIREQNVQVSSGQLGGQPAVRGQQLNATVIGPSRLQTPEAFGRILLKVNRDGSQVRLKDVASIELGAQTYAIDSYYNGKPASGLAIKLASGANALDTAQAVRETINGLKPYFPPGMDVVYPYDTTPFVSLSIEGVVKTLFEAVLLVFLVMYLFLQNVRATLIPTLAVPVVLLGTFGVLAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLSPRQATRKSMGQITGALIGIAMVLAAVFVPMAFFGGSTGVIYRQFSITIVSSMVLSVVVAIVFTPALCATMLKPIPKGHHGSKKGFFGWFNRTFERSSQAYANNVARSMGRTKRLLLIYVVILLGMAWMFMRIPTAFLPDEDQGILFAQVQAPAGATSERTQATIDAAVKYLLEDEKESVASVFAVNGFSFGGRGQNAAILFIKLRDWNERKGAEHRAAAVAARANAKFRAELRDAQAAVFAPPAVMELGNATGFDFQLQDRAGVGHEKLLAARNQLLQEAGASPMLVAVRPNGIEDAPQYQLDIDREKARALGVSITEINNTLATAWGSSYVNDFIDRGRVKKVFVQGEASSRMLPQDLDKWYVRNNAGDMVPFSAFSSAQWTFGPQKLNRYNGVPSYNIQGQAAPGYSSGDAMAEMERLADKLPLGIGYDWTGLSFEERLSGAQAPALYAISLIVVFLCLAALYESWSIPTAVMLVVPLGVVGALLATMTRGLSNDVYFQVGLLTTIGLAAKNAILIVEFAKEHYEEGASLTEAAVHAARQRLRPILMTSLAFILGVVPLAISTGAGSGSQNAIGTGVIGGMLTGTFLAIFFVPLFFVLTLRLFKVKRASENREDDDPHGGAQPATHGGQPQ
>NZ_CP018039.1|WP_014486063.1|1008383_1009766_+|efflux-transporter-outer-membrane-subunit
MKPVVMRTLLSLAVATALAGCSLAPTYERPQAPVDAAYPSGPAYGAPGQAAAGAPAAADVGWRDFFGDPLLQELLALSLANNRDLRVAALNVEAARLNPSGQAGISRSYQVGASLSTWELDLFGRIRSLSEQALQLYLAQDETRLATQLTLVAETANAYLTLRADQELLALTRQTLAAQQESYKLTRQSYDLGVATELDLSQAEISLRTAERNLSQYTRMAAQDRNALVLLVGQPLPAGIGAQLDQAVALPDGVVLADLPAGLPSDLLARRPDIRAAEHQLQAANASIGAARAAFFPRISLTGSAGTASASLGGLFDAGSGAWSFAPQISVPIFAGGALRASLDLAKIQKDIGIARYEQAIQSGFREVSDALAGRGTLQEQIRSQELLVQANQRAYDLSQQRYQQGIDNYLSVLDSQRSLYTAQQTLVETRLARLSNLIQLYKALGGGWSERTVAAAQAG
>NZ_CP018039.1|WP_010930123.1|1009835_1010087_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MNIIIMIIVGFVVGLITRAIMPGDQNMGYIMTTILGIIGSVVAGFLGQQLGWYAPGEPAGWIGSVVGAIIVLFVVGLVAKKRA

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Crispr_ID: NZ_CP018039_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018039_4

1819234-1819361

Orphan

Consensus_repeat	Method
AAAAAGCCCCCTCGGGGGGCAGCAAGCCCGCATAGCGGGCGCAGCG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP018039_4

>merge|NZ_CP018039|4|1819234-1819361|CRISPRCasFinder
AAAAAGCCCCCTCGGGGGGCAGCAAGCCCGCATAGCGGGCGCAGCGTGGGGGCACTACTTTGCCGCTGGGCCGCCCCAAGGCAAAAAGCCCCCTCGGGGGGCAGCAAGCCCGCGTAGCGGGCGCAGCG

>NZ_CP018039|4|4|1819234-1819361|CRISPRCasFinder
AAAAAGCCCCCTCGGGGGGCAGCAAGCCCGCATAGCGGGCGCAGCG	TGGGGGCACTACTTTGCCGCTGGGCCGCCCCAAGGC
AAAAAGCCCCCTCGGGGGGCAGCAAGCCCGCGTAGCGGGCGCAGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018039.1\|WP_010930571.1\|1827598_1829461_+\|Fe-S-protein-assembly-chaperone-HscA	unknown	unknown	gnl\|CDD\|235360
NZ_CP018039.1\|WP_003820159.1\|1816023_1816509_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP018039.1\|WP_003812456.1\|1826956_1827469_+\|Fe-S-protein-assembly-co-chaperone-HscB	unknown	unknown	gnl\|CDD\|235133
NZ_CP018039.1\|WP_010930568.1\|1821443_1823480_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP018039.1\|WP_010930570.1\|1824969_1826181_+\|IscS-subfamily-cysteine-desulfurase	unknown	unknown	gnl\|CDD\|184450
NZ_CP018039.1\|WP_003812460.1\|1826218_1826629_+\|Fe-S-cluster-assembly-scaffold-IscU	unknown	unknown	gnl\|CDD\|183087
NZ_CP018039.1\|WP_019247244.1\|1820163_1821366_-\|aspartate/tyrosine/aromatic-aminotransferase	unknown	unknown	gnl\|CDD\|181731
NZ_CP018039.1\|WP_010930651.1\|1813248_1815234_-\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	unknown	unknown	gnl\|CDD\|274868
NZ_CP018039.1\|WP_003812458.1\|1826630_1826954_+\|iron-sulfur-cluster-assembly-protein-IscA	unknown	unknown	gnl\|CDD\|213674
NZ_CP018039.1\|WP_010930652.1\|1815442_1815679_+\|membrane-protein	unknown	unknown	unknown
NZ_CP018039.1\|WP_003820151.1\|1807786_1808086_+\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|223713
NZ_CP018039.1\|WP_003812472.1\|1819384_1820113_-\|transcriptional-repressor-LexA	unknown	unknown	gnl\|CDD\|234688
NZ_CP018039.1\|WP_005012067.1\|1816876_1817827_+\|IS481-like-element-IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018039.1\|WP_015041299.1\|1809255_1809894_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372868
NZ_CP018039.1\|WP_003820153.1\|1809874_1811134_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|236882
NZ_CP018039.1\|WP_010930569.1\|1823732_1824224_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP018039.1\|WP_003812463.1\|1824439_1824952_+\|Fe-S-cluster-assembly-transcriptional-regulator-IscR	unknown	unknown	gnl\|CDD\|273927
NZ_CP018039.1\|WP_010930650.1\|1811137_1813243_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	unknown	unknown	gnl\|CDD\|274867
NZ_CP018039.1\|WP_153302780.1\|1816719_1816890_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018039.1\|WP_010930648.1\|1808138_1809251_+\|alkene-reductase	unknown	unknown	gnl\|CDD\|239243

Protein	Function_ID	Function_description	E-value
NZ_CP018039.1\|WP_010930571.1\|1827598_1829461_+\|Fe-S-protein-assembly-chaperone-HscA	gnl\|CDD\|235360	PRK05183, hscA, chaperone protein HscA; Provisional.	0
NZ_CP018039.1\|WP_003820159.1\|1816023_1816509_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	7.77331e-19
NZ_CP018039.1\|WP_003812456.1\|1826956_1827469_+\|Fe-S-protein-assembly-co-chaperone-HscB	gnl\|CDD\|235133	PRK03578, hscB, Fe-S protein assembly co-chaperone HscB.	2.55481e-79
NZ_CP018039.1\|WP_010930568.1\|1821443_1823480_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP018039.1\|WP_010930570.1\|1824969_1826181_+\|IscS-subfamily-cysteine-desulfurase	gnl\|CDD\|184450	PRK14012, PRK14012, IscS subfamily cysteine desulfurase.	0
NZ_CP018039.1\|WP_003812460.1\|1826218_1826629_+\|Fe-S-cluster-assembly-scaffold-IscU	gnl\|CDD\|183087	PRK11325, PRK11325, scaffold protein; Provisional.	5.84746e-99
NZ_CP018039.1\|WP_019247244.1\|1820163_1821366_-\|aspartate/tyrosine/aromatic-aminotransferase	gnl\|CDD\|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
NZ_CP018039.1\|WP_010930651.1\|1813248_1815234_-\|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA	gnl\|CDD\|274868	TIGR03939, PGA_TPR_OMP, poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats.	1.10027e-119
NZ_CP018039.1\|WP_003812458.1\|1826630_1826954_+\|iron-sulfur-cluster-assembly-protein-IscA	gnl\|CDD\|213674	TIGR02011, Protein_yfhF., iron-sulfur cluster assembly protein IscA. This model represents the IscA component of the ISC system for iron-sulfur cluster assembly. The ISC system consists of IscRASU, HscAB and an Isc-specific ferredoxin. IscA previously was believed to act as a scaffold and now is seen as an iron donor protein. This clade is limited to the proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	4.04388e-54
NZ_CP018039.1\|WP_003820151.1\|1807786_1808086_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	1.67046e-14
NZ_CP018039.1\|WP_003812472.1\|1819384_1820113_-\|transcriptional-repressor-LexA	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	1.30999e-106
NZ_CP018039.1\|WP_005012067.1\|1816876_1817827_+\|IS481-like-element-IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	8.66858e-23
NZ_CP018039.1\|WP_015041299.1\|1809255_1809894_-\|hypothetical-protein	gnl\|CDD\|372868	pfam13994, PgaD, PgaD-like protein. This family includes the PgaD protein from E. coli. The homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (beta-1,6-GlcNAc; PGA) serves as an adhesin for the maintenance of biofilm structural stability in eubacteria. The pgaABCD operon is required for its synthesis and export. It has been shown that PgaD is essential for this process.	0.00341018
NZ_CP018039.1\|WP_003820153.1\|1809874_1811134_-\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	0
NZ_CP018039.1\|WP_010930569.1\|1823732_1824224_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	1.04407e-74
NZ_CP018039.1\|WP_003812463.1\|1824439_1824952_+\|Fe-S-cluster-assembly-transcriptional-regulator-IscR	gnl\|CDD\|273927	TIGR02010, Putative_HTH-type_transcriptional_regulator, iron-sulfur cluster assembly transcription factor IscR. This model describes IscR, an iron-sulfur binding transcription factor of the ISC iron-sulfur cluster assembly system. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Regulatory functions, DNA interactions].	1.00126e-77
NZ_CP018039.1\|WP_010930650.1\|1811137_1813243_-\|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB	gnl\|CDD\|274867	TIGR03938, hypothetical_protein_Pcar_2791, poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB. Two well-characterized systems produce polysaccharide based on N-acetyl-D-glucosamine in straight chains with beta-1,6 linkages. These are encoded by the icaADBC operon in Staphylococcus species, where the system is designated polysaccharide intercellular adhesin (PIA), and the pgaABCD operon in Gram-negative bacteria such as E. coli. Both systems include a putative polysaccharide deacetylase. The PgaB protein, described here, contains an additional domain lacking from its Gram-positive counterpart IcaB (TIGR03933). Deacetylation by this protein appears necessary to allow export through the porin PgaA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP018039.1\|WP_010930648.1\|1808138_1809251_+\|alkene-reductase	gnl\|CDD\|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	0

>NZ_CP018039.1|WP_005012067.1|1816876_1817827_+|IS481-like-element-IS481-family-transposase
MNTHKHARLTFLRRLEMVQQLIAHQVCVPEAARAYGVTAPTVRKWLGRFLAQGQAGLADASSRPTVSPRAIAPAKALAIVELRRKRLTQARIAQALGVSASTVSRVLARAGLSHLADLEPAEPVVRYEHQAPGDLLHIDIKKLGRIQRPGHRVTGNRRDTVEGAGWDFVFVAIDDHARVAFTDIHPDERFPSAVQFLKDAVAYYQRLGVTIQRLLTDNGSAFRSRAFAALCHELGIKHRFTRPYRPQTNGKAERFIQSALREWAYAHTYQNSQHRADAMKSWLHHYNWHRPHQGIGRAVPISRLNLDEYNLLTVHS
>NZ_CP018039.1|WP_153302780.1|1816719_1816890_+|hypothetical-protein
MQNSSVYALSYPARPGLQASCEDSIGCMHGSSEPDLRNWKSPPPQFTQGARPDEHP
>NZ_CP018039.1|WP_003820159.1|1816023_1816509_+|winged-helix-turn-helix-transcriptional-regulator
MPASQDKPDVPPGPYHFSEQVGHLLRRAYQRHVAIFQQTIPDSKLTAAQFVVLCALRDQGACSLVDVVKATAIDQATVRGVIERLKARKLLAVSHDPADRRKVLVTLTPDGRALVEEMVPFAEQITQSTFGGLNPAERVAIVYLLRKMSDADDLVGRQSES
>NZ_CP018039.1|WP_010930652.1|1815442_1815679_+|membrane-protein
MRRAAKWWGPAATWTLAALLVLLVGHGVVPEAARVSDAPLLHAMAGHAYLLNWAAGLMALIGWGDSLVLYRRTRRRAV
>NZ_CP018039.1|WP_010930651.1|1813248_1815234_-|poly-beta-1,6-N-acetyl-D-glucosamine-export-porin-PgaA
MNNDQTRRTRPASVRGLRRTRLLVAGLAFVGAAAAAAPSVRDQVQEASRSGAANLALDLATEHRALFTPLEYAQLQHAAIAQRLRWSRAETWNLTGPERFATLDAALADGWQLLDSLPLAPEYASLRTAVISDMIYGLGLRGRYADAIKLYEGLRATNTPVHPYVLVSAGNAYAYEERYDEAIVCYEEALAKAGPGDIDRVPTQESLFFAYMDRGRYEDAEQLLQRIEKTSPQYVENAPVAERPNEDYATAQRLRAQYLMYSGETEAGTLAIDALQHDAPFSSGLRNAAASARLGDARPREAKAAFTTALAERPDDIQAMTGLARASMALREYPEAEAIVTTLSERFPESSSVRNLQRDYEVYQSPLLTMDFGGDIGHGGDNSNNDNSTIANREWSLNTMLYTSPISHNYRLFFHQFTGYADLGDGHKSRVRNGAGLEYRRGSIEASTELHQSTGPSGRFGASANVAWLPSDGWRLAANFDSDSNDLPWKAYRAGIHGWSSGVSARYQPTERTYYDVAYQLQHYSDSNTRQTIGATWFQNLWTVPRHSVSTWTSVAYSNNSKTDTECFSPDHDLTAQVTAMYEWRPWRDGQYAFRQRVYATGGVYNQAEHGNSALWQLRLEQVWDLPRQTSITYGVGYGRHSYDGDPENRTLFYLTLNIPF
>NZ_CP018039.1|WP_010930650.1|1811137_1813243_-|poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase-PgaB
MTAMHRTLLKWFACCALGLLMLPARAYKVDMLPPPDPDDGLTFRVLCMHDVRDNLRASFADMPDQFAIETRTLTDLFEWIRVKGFNLISMQQIIDSRAGVRPLPPRPILLTFDDGYASTYTKVFPLLKKFNYPAVVAVVTSWTDAPAGTKIRLSPKIEVPHDFFMTWAQLREMAQSGLVELASHSHNLHRGVLANPQGNEQPAASSRQYLPASGRYENDAEYRARVRQDLKTSADLIREHTGVTIRSIVWPYGAHNRDTDQVAAEVGLNIGLTLQPGPNTPDVSLTQIRRSLVDYEVNVATVARAMREPVSYHGQVRPIERIVQVDLDYIYDPDPEQQNRNLGQLIDRMKDLAPSAVYLQAFAYPKGDGDITEVYFPNRHLPMRADLFNRVAWQLKTRAGVMVYAWLPVLTFSVPPGNPAYGKVVQSTTRKPGERGLGSPTRLSPFHPDAHRVISEIYEDLAKAAHFDGLLFHDDAVLDDTEDSSPEALATYQGWGLPPDIAAIRADPKLAQQWSKGKIRYLIDFTMHLRHIVSGYQNDRDMVVARNLYAQPVLDPVSEAWYGQSLPEFLKSYDFVALMAMPNMEGAARPEQWMRQLVAAVARQKGLDRTIFELQARDWRVGKPIDTEILRKQMVQLRSLGAINYGYYPDDFIANHPDAEVLRDVMSLKSTLEKRRLTKAQELSRQTTLYGSASQAEPTQR
>NZ_CP018039.1|WP_003820153.1|1809874_1811134_-|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MNDSVKSVLSSFVFYYPFFMSYFWIVGGLLHFFLFEQGRKHRATLLPRVPRVAIVVPCYNEGENVAEVIAHLDRMHYPNYRIIAVNDGSRDNTGALLNELAEQYPRLLVVHQSRNEGKAIGLNTAAQLSDAEFLLCIDGDSLPHPDSITYMLTHFLHAGHVGAVTGNPRIRNRSTVLGRMQVGEFSSIVGLIKRTQQLYGKLMTVSGVMTMFRKQALHQVGYWSPDMQTEDIDISWKLQLAGWTLRYEPRALTWILMPETFRGLFKQRYRWARGGIETALKYAPRMLNPRQILMWPIFLEFSLSVLWAYAMLFLICMAVLGQFVALPPAWQFEIFPRWHGTLLFLTCLAQLFAGCIVDRAYDYRIFRYFADAVWYPIAFWIIGMITTVFALPRVLFRRAQSRARWVSPDRGIKHESVDH
>NZ_CP018039.1|WP_015041299.1|1809255_1809894_-|hypothetical-protein
MKALIIDISASPLREYVHQHGVADGLLYGCWYRIVRPLLVILTWVAFSLYIHHSLVTVGGTAAQIAELLVYITVVATMAAALTAWMIVCRFHGWIRARDNEEVGVGLDPEYALPPRWPLPEGANRLLVDHDEAGAIVQVSAWYVPAAIEPVVAAAMASAVMPEAAPLSEPAPVAAALPDEADELAAWSGPPMQRQPDGRIEPTLHDGRALTL
>NZ_CP018039.1|WP_010930648.1|1808138_1809251_+|alkene-reductase
MSTLFQPLNAGKLRLANRIVMAPLTRNRSPNAVPPPLTATYYAQRASAGLIITEATAISHQGQGYADVPGLYAPEQLAGWRRVTDAVHAAGGTIVVQLWHVGRISHTTLQPGQGAPVAPSAIRAQARTYLVDAQGKGQFADTSEPRALALDELPGIVEDYRRAARAAIDHGFDGVELHAANGYLLDQFLRSGSNHRDDAYGGSIENRARLLLRALDAVCAEVGADRVGIRLSPVTPANDAHDDQPQPLFEYVLRELARRGLAYVHVIEGATGGDRAYQQGPAPFDYAALKAAYRAAGGAGAWMVNNGYDISLAEQKLSSGQADLVAFGKPFIANPDLVARLRQGAALNEGDRDTFYGGGERGYTDYPALA
>NZ_CP018039.1|WP_003820151.1|1807786_1808086_+|helix-turn-helix-transcriptional-regulator
MAINTEDILKALAHPARRNILAWLKEPQRHFPQQEHPLELGVCAGQFERCGLSQSTVSTHLAILQRAGLIHSRRVGQWVFYQRNEACIAEFLQTMQAEL
>NZ_CP018039.1|WP_003812472.1|1819384_1820113_-|transcriptional-repressor-LexA
MRLAFFPWVLQNGAVYPYSPQKRVIAMATKLTERQQEILDLIRQTVARTGFPPTRAEIAQALGFRSPNAAEDHLKALARKGAIELTAGASRGIRLKVPDSATPSAQLTHPLLAQLVLPLVGRVAAGSPILASEHVEREVGVDPGLFAQTPDYLLKVRGMSMRDAGILEGDLLAVKRAAEARNGQIVVARLGDEVTVKRLQRQNGRIELLPENPDFAPIVVANTDEFALEGIAVGLIRTQPLH
>NZ_CP018039.1|WP_019247244.1|1820163_1821366_-|aspartate/tyrosine/aromatic-aminotransferase
MSTLFASVELAPRDPILGLNEQYNADTRPGKVNLGVGVYYDDEGRIPLLQAVRKAEVARIEAAAARGYLPIEGIAGYNKGAQALLLGADSPLAAEGRVLTAQALGGTGALKIGADFLRQLLPQSKVLISDPSWENHRALFERAGFPVETYAYYDAATHGLNFEAMLAALQAAPEQTIVVLHACCHNPTGVDPTPQQWEQIAAVVKARNLVPFLDIAYQGFGEGLEQDAAVVRMFAELDLTMFISSSFSKSFSLYGERVGALTVVAGSKDEAARVLSQLKRVIRTNYSNPPTHGGTVVSTVLNTPELFALWENELAGMRDRIRLMRKELVEKIKTQGVAQDFSFVLAQRGMFSYSGLTAAQVDRLREEHGIYAVSSGRICVAALNSRNIDAVAAGIAAVLK
>NZ_CP018039.1|WP_010930568.1|1821443_1823480_+|excinuclease-ABC-subunit-UvrB
MTAPGFVEFPDSPFHLYQPYPPAGDQPGAIDALTEGVSDGLMFQTLLGVTGSGKTYTMANMIARLGRPALVLAPNKTLAAQLYAEMREFFPRNAVEYFVSYYDYYQPEAYVPTRDLFIEKDSSINEHIEQMRLSATKSLLERRDTVIVGTVSCIYGIGNPGDYHAMVLILRTGDRISRREVLARLVAMQYTRNDADFTRGVFRVRCETIDIFPAESPELALRLTLFDDEIESLELFDPLTGRVRQKLPRFTVYPGSHYVTPRETVLRAIETIKEELRERLAQLIADGKLVEAQRLEQRTRFDLEMLQELGFCKGIENYSRHLSGAAPGEPPPTLIDYLPADALMFIDESHVTIGQLGGMYRGDRSRKETLVQYGFRLPSALDNRPLRLEEFEARMRQCVFVSATPAAYEQEHADNVVEQVVRPTGLVDPIVEVRPAHTQVDDLLGEIHKRAALQERVLVTTLTKRMAEDLTDFLSEHGVRVRYLHSDIDTVERVEIIRDLRLGVFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGRAILYADRITDSMRRAIDETERRRAKQIQHNTDHGITARGVSKAVRELIDGVVAPAGHDALESAVPAEVLTDEKAMAREIRRLEKLMMDHARNLEFEQAAAARDALNALKSRLLLDGVGWSG
>NZ_CP018039.1|WP_010930569.1|1823732_1824224_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MMTKVLFVCMGNICRSPSAEGVFRYLVNDAGMGDVVRVDSAGTHAFHIGEAPDARAQAAARKRGYDLTHCAARQVTADDFREFDLILAMDWDNLAALQQQCPKAYQHKLMLLMRFANEFEEATVPDPYYGGPEGFGKVLDYLEDACQGVLELVRKRATQYQAA
>NZ_CP018039.1|WP_003812463.1|1824439_1824952_+|Fe-S-cluster-assembly-transcriptional-regulator-IscR
MRLTTKGRFAVTAMIDLAMRQHSGPVTLAAISQRQNISLSYLEQLFGKLRRHELVDSVRGPGGGYSLARLARNVTVADIIFAVDEPLDATSCGGKRDCTSGNDGKPGKCMTHELWTTLNRKMVDYLDSVSLQDLVDQQRVRQLQEAANQAQGCSAVRVNRSTPVAANATA
>NZ_CP018039.1|WP_010930570.1|1824969_1826181_+|IscS-subfamily-cysteine-desulfurase
MSNRPIYLDYSATTPVDPSVVEKMIPWLYESFGNPASRSHAFGWEAEDAVEKAREEVAKLVNADPREIVWTSGATESDNLAIKGAANFYAERGKHIITVKTEHKAVLDTCRELERQGFEVTYLDVQDDGLLSLDAFKAALRPDTILVSVMMVNNEIGVIQDIAALGEICREKGIIFHVDAAQATGKVEIDLQKLKVDLMSFSAHKTYGPKGIGALYVRRKPRVRIEAQMHGGGHERGFRSGTLATHQIVGMGEAFRLAREEMGTENERVRMLRDRLLAGLTQIEEVYVNGSMEHRVPHNLNISFNYVEGESLIMAIKELAVSSGSACTSASLEPSYVLRALGRNDELAHSSIRFTLGRFTTEQEIDFTIELIKSRVGKLRDMSPLWEMAQEGIDLNSVQWAAH
>NZ_CP018039.1|WP_003812460.1|1826218_1826629_+|Fe-S-cluster-assembly-scaffold-IscU
MAYSSKVLDHYENPRNVGSFDKGDDSVGTGMVGAPACGDVMKLQIKVNEAGVIEDARFKTYGCGSAIASSSLVTEWVKGKTLDEAMNIRNTQIAEELALPPVKIHCSILAEDAIKAAVQDYKTKHGAETPEAVAAN
>NZ_CP018039.1|WP_003812458.1|1826630_1826954_+|iron-sulfur-cluster-assembly-protein-IscA
MAVTLTQSAANHVGRYLQKRGKGIGLRLGVRTTGCSGMAYKLEYVDEQAADDVVFDSFGVKVFIDPKSLAYLDGTELDYAREGLNEGFRFSNPNEKATCGCGESFTV
>NZ_CP018039.1|WP_003812456.1|1826956_1827469_+|Fe-S-protein-assembly-co-chaperone-HscB
MAADDHFSLFGLPTRFALDPVQLEQAWRAVAARVHPDRYATASAAERRVAMQWAARANEAYRQLRDPMLRARYLCEQAGVDLQTESNTAMDPAFLMQQMEWREMLDDARRDPAAFAALRAELEQARLRMQQTLSELIDERGDYQQAGTKVREWMFVEKLAQELSAAQPMQ
>NZ_CP018039.1|WP_010930571.1|1827598_1829461_+|Fe-S-protein-assembly-chaperone-HscA
MALLQISEPGDSPAPHQRKLAVGIDLGTTNSLVAAVRSSVPEVLADAQGQVLLPSAVRYLDGGAVRIGREALLEQARDPLNTIVSVKRFMGRSAADAAASGAPYEFVDAPGMVRLRTVQGDLSPVEVSAQILAVLRQRAEDVLGDDLVGAVITVPAYFDDAQRQATRDAARLAGLNVLRLLNEPTAAAIAYGLDQAAEGIYAVYDLGGGTFDISILRLTQGVFEVIATGGDTALGGDDFDSAIVAHACAGEDVAALPVADRRALLVAARAAREALTDQAQAPFEVTLRDGRAIQATLTRAQFEQLAEPLVGRTLDSARRALRDAGLAVGDVRGVVMVGGATRMPVVRQQVGALFGTEPLTNLDPDQVVALGAALQANLLAGNRALGEDWLLLDVIPLSLGLETMGGLVERIIPRNSTIPVARAQEFTTFKDGQTAMSVHVVQGERDLVSDCRSLARFELRGIPPMVAGAARIRVTFQVDADGLLSVTAREQSTGVEAAVAVKPSYGLSDDEIARMLADSVTQADSDARARMLREQQVEARQLVESVGAALAADGDLLDPAERATVDQRLQAAAQAQSLDDVEAVRAAVQALSDATEEFAARRMDRSIRSALAGRKLDELA

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Crispr_ID: NZ_CP018039_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018039_5

3433971-3434080

Orphan

Consensus_repeat	Method
TTGACTGCCAAGACGGTATCTGTCCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018039_5

>merge|NZ_CP018039|5|3433971-3434080|CRISPRCasFinder
TTGACTGCCAAGACGGTATCTGTCCCCGCAGGGAGGGTGCCTGTCCCCGCCGGGACAGGCACACTGCTGTACGCCATCGACGCTTGACGGCCAAGACGGTATCTGTCCCC

>NZ_CP018039|5|5|3433971-3434080|CRISPRCasFinder
TTGACTGCCAAGACGGTATCTGTCCCC	GCAGGGAGGGTGCCTGTCCCCGCCGGGACAGGCACACTGCTGTACGCCATCGACGC
TTGACGGCCAAGACGGTATCTGTCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018039.1\|WP_003814739.1\|3431932_3432718_+\|enoyl-ACP-reductase-FabI	unknown	unknown	gnl\|CDD\|180789
NZ_CP018039.1\|WP_019247959.1\|3420637_3423616_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375438
NZ_CP018039.1\|WP_003818344.1\|3424542_3425421_+\|fatty-acid-desaturase	unknown	unknown	gnl\|CDD\|366126
NZ_CP018039.1\|WP_080501793.1\|3420270_3420684_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018039.1\|WP_005013747.1\|3427369_3428320_+\|IS481-like-element-IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018039.1\|WP_010931353.1\|3418249_3419338_+\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187652
NZ_CP018039.1\|WP_010927090.1\|3429617_3430418_+\|hydroxyacylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|274569
NZ_CP018039.1\|WP_010931358.1\|3435296_3436295_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270296
NZ_CP018039.1\|WP_003814239.1\|3438818_3439520_+\|response-regulator	unknown	unknown	gnl\|CDD\|181883
NZ_CP018039.1\|WP_003814742.1\|3434081_3434474_-\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|224679
NZ_CP018039.1\|WP_010931355.1\|3428826_3429597_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|369777
NZ_CP018039.1\|WP_010931357.1\|3434611_3435292_+\|tellurite-resistance-TerB-family-protein	unknown	unknown	gnl\|CDD\|377342
NZ_CP018039.1\|WP_010931362.1\|3445343_3446222_+\|septum-site-determining-protein-MinC	unknown	unknown	gnl\|CDD\|178806
NZ_CP018039.1\|WP_010931361.1\|3442012_3443353_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP018039.1\|WP_010931360.1\|3440960_3442016_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP018039.1\|WP_010927010.1\|3439519_3440944_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236531
NZ_CP018039.1\|WP_010930179.1\|3436363_3437314_-\|IS481-like-element-IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP018039.1\|WP_003820957.1\|3443468_3445232_+\|glutamine--tRNA-ligase/YqeY-domain-fusion-protein	unknown	unknown	gnl\|CDD\|235424
NZ_CP018039.1\|WP_010931356.1\|3430428_3431838_+\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|182727
NZ_CP018039.1\|WP_010931354.1\|3428316_3428784_-\|ribonuclease-HI	unknown	unknown	gnl\|CDD\|178927

Protein	Function_ID	Function_description	E-value
NZ_CP018039.1\|WP_003814739.1\|3431932_3432718_+\|enoyl-ACP-reductase-FabI	gnl\|CDD\|180789	PRK06997, PRK06997, enoyl-[acyl-carrier-protein] reductase FabI.	1.22848e-177
NZ_CP018039.1\|WP_019247959.1\|3420637_3423616_+\|hypothetical-protein	gnl\|CDD\|375438	pfam17936, Big_6, Bacterial Ig domain. This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.	1.32844e-07
NZ_CP018039.1\|WP_003818344.1\|3424542_3425421_+\|fatty-acid-desaturase	gnl\|CDD\|366126	pfam00487, FA_desaturase, Fatty acid desaturase.	2.20669e-12
NZ_CP018039.1\|WP_010931360.1\|3440960_3442016_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	1.57809e-49
NZ_CP018039.1\|WP_005013747.1\|3427369_3428320_+\|IS481-like-element-IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	9.05216e-23
NZ_CP018039.1\|WP_010931357.1\|3434611_3435292_+\|tellurite-resistance-TerB-family-protein	gnl\|CDD\|377342	pfam04391, DUF533, Protein of unknown function (DUF533). Some family members may be secreted or integral membrane proteins.	5.6465e-62
NZ_CP018039.1\|WP_010927090.1\|3429617_3430418_+\|hydroxyacylglutathione-hydrolase	gnl\|CDD\|274569	TIGR03413, GSH_gloB, hydroxyacylglutathione hydrolase. Members of this protein family are hydroxyacylglutathione hydrolase, a detoxification enzyme known as glyoxalase II. It follows lactoylglutathione lyase, or glyoxalase I, and acts to remove the toxic metabolite methylglyoxal and related compounds. This protein belongs to the broader metallo-beta-lactamase family (pfam00753). [Cellular processes, Detoxification].	2.85848e-146
NZ_CP018039.1\|WP_010931358.1\|3435296_3436295_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	7.76869e-129
NZ_CP018039.1\|WP_003814239.1\|3438818_3439520_+\|response-regulator	gnl\|CDD\|181883	PRK09468, ompR, osmolarity response regulator; Provisional.	4.05363e-90
NZ_CP018039.1\|WP_003814742.1\|3434081_3434474_-\|OsmC-family-protein	gnl\|CDD\|224679	COG1765, COG1765, Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones].	4.86152e-16
NZ_CP018039.1\|WP_010931355.1\|3428826_3429597_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	9.0439e-10
NZ_CP018039.1\|WP_010931353.1\|3418249_3419338_+\|NAD(P)H-binding-protein	gnl\|CDD\|187652	cd08948, 5beta-POR_like_SDR_a, progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs. 5beta-POR catalyzes the reduction of progesterone to 5beta-pregnane-3,20-dione in Digitalis plants. This subgroup of atypical-extended SDRs, shares the structure of an extended SDR, but has a different glycine-rich nucleotide binding motif (GXXGXXG) and lacks the YXXXK active site motif of classical and extended SDRs. Tyr-179 and Lys 147 are present in the active site, but not in the usual SDR configuration. Given these differences, it has been proposed that this subfamily represents a new SDR class. Other atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.76863e-97
NZ_CP018039.1\|WP_010931361.1\|3442012_3443353_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.21087e-123
NZ_CP018039.1\|WP_010931362.1\|3445343_3446222_+\|septum-site-determining-protein-MinC	gnl\|CDD\|178806	PRK00030, minC, septum site-determining protein MinC.	3.47756e-166
NZ_CP018039.1\|WP_010927010.1\|3439519_3440944_+\|HAMP-domain-containing-protein	gnl\|CDD\|236531	PRK09467, envZ, osmolarity sensor protein; Provisional.	3.78414e-42
NZ_CP018039.1\|WP_010930179.1\|3436363_3437314_-\|IS481-like-element-IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.3142e-23
NZ_CP018039.1\|WP_003820957.1\|3443468_3445232_+\|glutamine--tRNA-ligase/YqeY-domain-fusion-protein	gnl\|CDD\|235424	PRK05347, PRK05347, glutaminyl-tRNA synthetase; Provisional.	0
NZ_CP018039.1\|WP_010931356.1\|3430428_3431838_+\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|182727	PRK10783, mltD, membrane-bound lytic murein transglycosylase D; Provisional.	5.28635e-76
NZ_CP018039.1\|WP_010931354.1\|3428316_3428784_-\|ribonuclease-HI	gnl\|CDD\|178927	PRK00203, rnhA, ribonuclease H; Reviewed.	4.07937e-102

>NZ_CP018039.1|WP_003814739.1|3431932_3432718_+|enoyl-ACP-reductase-FabI
MGFLAGKRILMTGVLSNRSIAYGIARACRDQGADLAFTYVGDRFKERITEFAASFGSDIVLPCDVAEDSQIDAAFAELGKRWDGLDGLVHAIGFAPREAIAGDFLDGLSRENFRIAHDISAYSFPAMAKAALPLMEGRKGSVLTLSYLGSERVVANYNTMGLAKASLEASVRYLATALGPRGIRANAISAGPIKTLAASGIKDFSSILKFVEANAPLRRNVTIEDVGNVAAFMLSDLAAGITGEITHVDAGFSTVVPGMEN
>NZ_CP018039.1|WP_010931356.1|3430428_3431838_+|transglycosylase-SLT-domain-containing-protein
MRFLRLLLPLFLAVLAGCAGTAKQNQAAGPSSNRYIAQDTSRTVDLTSPPSDAWDRIRRGFAIPNLNTDLAQEWTDYYASHPESVQRMAERAGKYLYFIVDEINRRGLPTELALLPFVESAYNPTALSRSQASGLWQFIPTTGQHFNLKQDWWRDERRDPIASTYAALDYLEKLFEMQGDWYLALASYNWGEGSVQRAMAKNEAAGLSTDYLSLNMPDETRNYVPKLQAIKNIIANPRKFAVVLPPVENTPYFVAVQKNRDIDIELAARLAEMPLDEFKALNPAFNRPLIRGEHAPTLLLPADRADRFNANLQNYKGDLSSWKVYHTRRGESYAAIAKRFGISEAKLRASNDIGSKRKVAADQALLIPGVPSGDGAANIQLASLSPPVGALDNVGEPRAAAAPRGKAPARVASARPNVRTHKVSSGDTLFGLARKYGTSVGALRALNNLKGNNLKLGSQLRIPGTGTRG
>NZ_CP018039.1|WP_010927090.1|3429617_3430418_+|hydroxyacylglutathione-hydrolase
MQTAPPLSAVVPLPAFSDNYIWALAHEGQAAVVDPGDAAPVLRWLRATGATLRAILLTHHHPDHVGGVLELVQATGATVYGPAGETLPHCDVRLAEGDRVTLPELALALEVLDVPGHTAGHIAYTGRAAGVERVLFCGDTLFAGGCGRLFEGTPAQMLDSLEKLSALPADTQVCCAHEYTLANLRWALAVEPANRTLQQWYQRAQELRNEGTPTLPSTIGQERETNPFLRTPHAAVAHAAAVWSGRSLATPVEVFAALRQWKNNFK
>NZ_CP018039.1|WP_010931355.1|3428826_3429597_-|methyltransferase-domain-containing-protein
MAEETPPIVELAEWFQTPPGQYVLAWEQAQFDEAVADIFGYYAWQVGLAEPNLLRANRMPFKAWVGAGVPPPELAQGWQACVAAAPEALPFESQSVDLLVLPHAFECAEAPHLVLREVERVLVPEGRVVISGFNPWSLWGARNLMPGMEAWLPLPLSAQVALPRLKDWFKLLSFEVERGRFGCYAPACRTDKWLRRWRFMERYGQRWWGLGGAVYVVTATKKVAAMRLIGPAWKTRRKRAQAASVVVNRQADDPGR
>NZ_CP018039.1|WP_010931354.1|3428316_3428784_-|ribonuclease-HI
MQNLEGSGDGQQVEMWTDGACKGNPGPGGWGVLMRAGQHEKTMHGGERQTTNNRMELMAVIEGLRALKRPCRVTIHTDSQYVMKGMTEWLANWKRRGWRTADKKPVKNVELWQALDEQVGRHQVQWRWVRGHAGDPGNERADALANQGMEAARGR
>NZ_CP018039.1|WP_005013747.1|3427369_3428320_+|IS481-like-element-IS481-family-transposase
MNTHKHARLTFLRRLEMVQQLIAHQVCVPEAARAYGVTAPTVRKWLGRFLAQGQAGLADASSRPTVSPRAIAPAKALAIVELRRKRLTQARIAQALGVSASTVSRVLARAGLSHLADLEPAEPVVRYEHQAPGDLLHIDIKKLGRIQRPGHRVTGNRRDTVEGAGWDFVFVAIDDHARVAFTDIHPDERFPSAVQFLKDAVAYYQRLGVTIQRLLTDNGSAFRSRAFAALCHELGIKHRFTRPYRPQTNGKAERFIQSALREWAYAHTYQNSQHRADAMKSWLHHYNWHRPHQGIGRAVPISRLNLDEYNLLTVHT
>NZ_CP018039.1|WP_003818344.1|3424542_3425421_+|fatty-acid-desaturase
MVRPAEWLRHRRDWQSVLYLAALPALAAWQWVHGWHWALYAPMLFLTLGVGVIHHNHAHRRMWRPRWLNRLTDFWLTLLQGHPTFVFHAAHNANHHRYKHGPRDVARTYRFGGDTNHLAGYLLHPLQAVVVLYPLFLASLRRLRSRRPGVWRYCLRQYAAWLGLWGGLLALDPGKAFWLVIVPQLHGLHWLLATNYLQHAHADGGPGRHAALSYARNFEGWVNPLLFNIGLHTAHHENPRAHWSELRALHWQHYRDRVPSRLNERGLAPYMARVFVLGLFSRRCRTHTLMRP
>NZ_CP018039.1|WP_019247959.1|3420637_3423616_+|hypothetical-protein
MQLWLPDGTATSVRANAAGGFEASSAGDMTSGLIRARATDRYGDTSQEVTYAYTDTVDKTAPVLSIAGVATDEATGRVTVTGRSEPDAQVTIRFPGGGRKTVRADANGAYRVRSDGDLPAGVIVVQAADAAGNSTQAQQAYQDTVDRTAPEPVQIALDTDAATGRLTVSGQAEPGGSVTVTWPDGTTQTVRVDADGGFRVTSAGDAAQGDVVVVVADQAGNRAAPVRAHYADPVDRTAPMTPTVRHATDAQTGRVTVMGRTEAGALVTVQFPDGSSKTVRAQNDGGYAATSDTDMVSGPIVVSAGDADGNRTPAQQVMYTDTLDKTAPASPSLTVREDAASGRATVTGQAEPGAAVRVVFPNGEAQTVTAGSDGAYSVTSTADMVAGEITVVAADASGNQSAPARTVFADAVDKTAPAAPTLALSEAADSGRLTVSGRTEPGASVRVTFPDGETVTVTAKADGTYTATSRADMIGGNVTVVATDTAGNAAAPVRAAYADTVDRTPPVLDTPVLNVASDSGRVTVTGVTEPGARVQVAIPGESLQTVTADSAGRYRAVSPGDVLQSGTVRVIATDAHGNASAPRDVPYQDAVDRTAPPLTIEAAVEQARTGVVNVSGKTEPNLMVSATFPDGQTAQARADGQGRYQLASPADVARSGRIAVSASDAAGNRAAARAEFTDQVDKTAPAVTIRAVTEQAGTGVATVSGATEPGATVSVTFPDGQVARATADRSGAYTVHSARDVTARGNISVIATDAAGNASPSVSRQFSNTVADTVPPSLTIAMVTTDPGNGRITVSGVTEAGARVHVVFPGGASDTVTADSKGGYRATSAGDVGSGAVTAQATDASANRSPLKTYAYTDAWQPRQLSAKDFSQSRYFVPLTTRGGTDNEPLLRITTNQQIPTAELRVALKPYKTEDRAGRLVREAITLKWGNAPGVGGDARALHFYVPDSAKAKLRKELTEVERSNDYKFWIEFTDTRFGGVARLYIKVISTL
>NZ_CP018039.1|WP_080501793.1|3420270_3420684_-|hypothetical-protein
MARTLVAVPSGSQSCMHVGQGLGDAVHGNAPGGRVGANLGNAQRQDDFLAPRIEHDAVLAPDEILQACAPVEWRGRVLRAAAQLPRQGLAQIQPHAQLDASCEDSIGCMHGSSEPDLRNWKSPPPQFTQGARPDEHP
>NZ_CP018039.1|WP_010931353.1|3418249_3419338_+|NAD(P)H-binding-protein
MTGSTAGKVLVVGALGVVGRAALEHFGQRPGLARVGLSRHAPDFAPEASWVSADLRDAQATRAALAAHGDATHVVYAALNEQPDLLKGWRDSGNVDLNTGMLRNTLDALREAPLRHVTLLQGTKAYGVHTGRPMPVPARETDAVRDHANFYFDQQDLLAERAAAQGFGWTIFRPQIVLGVALGSAMNPVATLGAYAALSREAGQPLRYPGHPHLLTECTDARLIARAIAWAWDEPRAHGEAFNIANGDVVLWQPVFERLAALFGMPLGEPVDTRMREAMPQLAERWRAIAERERLAVPELRDLIGLSWQYADATWAARHPLPVPPLVSTIKLRQAGFGDCIDTQDCIVEHLREMQRLRYLPR
>NZ_CP018039.1|WP_003814742.1|3434081_3434474_-|OsmC-family-protein
MTIQVRANTPGGLQYTATAEGHELPLAMPQPQGEGPDPHDYFDTALGGCKALTLMVYAQRKGLPLQAVDVDVVRDASEERKGIYRLTAKLKLHGDLDDAQIDELLKVADKCPLHKLMTATDIQVSTIVVE
>NZ_CP018039.1|WP_010931357.1|3434611_3435292_+|tellurite-resistance-TerB-family-protein
MSARQLLDQLLQSGQSLMQGAGAQAQQATQGGKGTFLAGLGGGALGAGALGLLLGSKKARKIGGKVAMYGGMAALGALAYRAYDQYQRNQAGGAAAPAPQTLDRLPPAPAEQHSNAVLVAMIGAAKADGHIGPDERQLLETELAKLSGDAGDRAWLEAELARPLDPAVIAQQARTPEMGAEMYLASLLVADEQSFMERAYLDELARQLKLPAELKQQLEAQVPAAA
>NZ_CP018039.1|WP_010931358.1|3435296_3436295_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MRPVAPMTTMKSQVSILLAGCLLGAGAAAAQAPATYPDHAITIVVTFPPGGGTDLLARKLGAAMQQRLGQPVVVENRPGASGNIGARAVAEARPDGYTLLMVNSSFAVNPGVFRNLDFSPTRDFTAVINVAYVPSVIVTAEPAGDAGLPERLRQADTQSRTLAFASCGNGTPQHLAGEMLRQASGAWLQHVPYRGCGPALTDVLSRQVPLGIVTASSAAPFIHAGKLRALAVTSAQRSPLLPDVPTVAEQGAPGYELDQWHGLLAPAGTPPAVIQRLYEALSAIVAEPAMRRELESLGFNPVSEGPERFEALVQADIARFAALTARMGLRAD
>NZ_CP018039.1|WP_010930179.1|3436363_3437314_-|IS481-like-element-IS481-family-transposase
MNTHKHARLTFLRRLEMVQQLIAHQVCVPEAARAYGVTAPTVRKWLGRFLAQGQAGLADASSRPTVSPRAIAPAKALAIVELRRKRLTQARIAQALGVSASTVSRVLARAGLSHLADLEPAEPVVRYEHQAPGDLLHIDIKKLGRIQRPGHRVTGNRRDTVEGAGWDFVFVAIDDHARVAFTDIHPDERFPSAVQFLKDAVAYYQRLGVTIQRLLTDNGSAFRSRAFAALCHELGIKHRFTRPYRPQTNGKAERFIQSALREWAYAHTYQNSQHRADAMKSWLHHYNWQRPHQGIGRAVPISRLNLDEYNLLTVHS
>NZ_CP018039.1|WP_003814239.1|3438818_3439520_+|response-regulator
MDNPHTKLLVVDDDPALRQLLADYLNRHGYDTLLAPDASDLAARITRYAPDLLVLDRMLPGGDGADACRRLRDQGEDIPVILLTARDEAVDRIIGLEAGADDYLGKPFDPRELLARIEAVLRRKRGPSALTKDAPVSFGPFVFDPATRQLLRDDTPVKLTGGEINLLEALVRNAGKPLSRERLLALARDDDGGERNDRAIDIAILRLRRAIEEDPKQPRWIQTVWGIGYRFSP
>NZ_CP018039.1|WP_010927010.1|3439519_3440944_+|HAMP-domain-containing-protein
MKLLRLPAPRSLRMRLILLVLGSVLLAQAATLATVSYFRHKFMEDVAIDYIATTIRTLRASLSQVPTDERAEFVRQASGNQWRLWSRSLPADARLQRWHRGPQEDEAERERMRREYERRHPPPDDIRRDLRGLVSELNERLSDGTRVALSRGPRPEIFISLAPSPSPDDAPPLREWLVIPLERLDPPVATPLIAFWVGGIGLVLLLAAWFSWHITRPLTRLADAADQLAAGQPQRVEPSGPHETRVLGERFNAMLDALAESDSVRRTLLSGLPHDLKGPLSRMWLRIEMADDPTLKEGLRKDLQDMQHMVDQFIGFVRGTDPAAYRYAPLALGEWLAERVGAWQGAGTDIRLQAPDNGALGIQADAVALGRLLDNLIGNALHHGAPPVEVSLRRDADMAVLEVSDHGPGIAPERRTEALRPFARLDDARTRTGNVGLGLALAEAIARAHGGGLELRQAPSGGLLVRITLPLAKA
>NZ_CP018039.1|WP_010931360.1|3440960_3442016_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MIATLAASLGLSPDDPSFWMPLVFVGLLLLLMAAGIVLDGFDIGVGLLLQLAPSEERGRMMGLLSPWRDANEFWPLLGLGLFVSAFPFAWGGVLGKLFGPLTVMALGMVLRSVSFEFRIRARTEIKPRWIFGFWVGSLLTALGQGMVLGRIATDYQADSGYGWFAFFVGLCVMAAYALLGACWLVMRVDGELQRRAAGWARHSIRWTAAGMVAIAVTLGLANAGIFYKWSNTAHLGVAAMVWALMLLGFVAAEMLLARLPGKADGFSWLPFVLCVMLFVLMLCGLAYSFFPYLILDDMTIWDGSGALDSMRLVLAGTVIGVPVVLVFNILAYRSVFGKERRPVPLLPPPGA
>NZ_CP018039.1|WP_010931361.1|3442012_3443353_-|cytochrome-ubiquinol-oxidase-subunit-I
MNIPPLLLARAQFTASLGFLALFLAISLALAWLLLFFKLRARWSGQSGWTAAYRFWVRIFALAFVLALACAVPVLIQLGSLWSGLMDKIGNLAGPLLGYGVLSIFIVKSCFLGVMLFGQRRVSDAAHTLAVLMVAIGQLVAVGWVLALFSWLQTPDGAVLIDGRYQVYDWRAVVLNPSFGWRLGLTVLGAFLTAGFLMLGVTAMQALRRPLDDGERHAFRAGLTVALLASLLLGPVAAGMGEVTARLQPAKAAAAAGFWHSGAEPELVVFGWPSARAQANLAAVSLAGAGGRWLHRDASLGYLGLDKFSGMQPPVAFTFWSLRLALGLGLLMLAASCATLALTCRRGFDPVALPRWWLRVLSLLMFAGALGVVATWCYDLAGMQPYAVNRAVTQSEVLGPVTTPALLYSLAGHIALYAVLLAAFVGMLFHAARYGVVPVRKTGGSS
>NZ_CP018039.1|WP_003820957.1|3443468_3445232_+|glutamine--tRNA-ligase/YqeY-domain-fusion-protein
MTHAPTPPAASNFLRPIIEDDLQANRFQGKLWAGKPGPAALQAQGQPDPARIRTRFPPEPNGYLHIGHAKSICVNFGLARDYGGVCHLRFDDTNPEKEEQEYVDAIIEAVHWLGFDWQADGNDNLYFASDYFEFMYEFAEALVQAGHAYVDEQSAEEIRASRGTLTEPGTDSPWRDRPADESLLRLREMRDGKHPDGSLVLRARIDMASPNINLRDPVMYRVRHATHHRTGNAWCIYPMYSWAHPVEDALEGITHSICTLEFEDQRPFYDWILARLAELGKLARPLPHQYEFARLNLTYVVTSKRKLLQLVREGYVDGWDDPRMPTLFGLRRRGYTPSSIRLFCDRTAVSKSDSRIDYSLLEQAVRDDLDPVAPRSVAVLDPLKLVITNYPEGRSETCSAPRNPHDPQAGVREFPFTRELWIEQDDFREEPPKKYFRLFPGNTVRLKYGYVVRCTGFTKDESGKVVEVQAEYLPDTKSGTPGADSVKVKGNITWVSAAHAVPAQVHLYDRLFADAHPDGGDKDFLACLNPNSKQTVQAWLEPGIEAVPGATWQFERLGYFTVDSKDSRPEAPVLNRIVTLRDSWQAA
>NZ_CP018039.1|WP_010931362.1|3445343_3446222_+|septum-site-determining-protein-MinC
MNTESLALDFKSATLYAIRVVLHDADTTRLRAALDKRMADAGSFFENEPVVIDATRVDAPVDWPALLQALADHNLPPIGVVAEGANLQGARDAGLVPVELSTSVARAPQVIDTAPPNDVATPVPSVPEATAEATAKAGPQDDEADGEQADEAPAHNPESVPTRAARETTEANRPTATPPQSSSALVITKPLRSGQRVYARHTDLIVIGMVSQGAEVIADGNVHVYGPLRGKAMAGARGDTSARIFTTQLDAELLAVAGVYRVVEDKLDRALHNQPALVRLDGDTLRIEALKG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

27282 : 70036

Synechococcus_phage(50.0%)

transposase,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010929577.1\|27282_28233_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_023995007.1\|28314_28650_-	CoA transferase	NA	NA	NA	NA
WP_010929578.1\|28674_29109_-	hypothetical protein	NA	NA	NA	NA
WP_010929579.1\|29141_30368_-	thiolase family protein	NA	NA	NA	NA
WP_010929580.1\|30364_30862_-	MaoC family dehydratase	NA	NA	NA	NA
WP_010929581.1\|31069_31978_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_023995008.1\|32163_33006_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_010929583.1\|33048_34470_+	MmgE/PrpD family protein	NA	NA	NA	NA
WP_010929584.1\|34625_35576_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_077108685.1\|35572_36763_-	MFS transporter	NA	NA	NA	NA
WP_003814400.1\|36949_37924_+\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_010929586.1\|37925_40064_+\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003814404.1\|40060_40600_+	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase	NA	NA	NA	NA
WP_003814405.1\|40603_41332_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_010929587.1\|41318_42212_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_019247766.1\|42282_42678_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_003814412.1\|42687_43218_+	peptide deformylase	E3SLL2	Synechococcus_phage	3.7e-12	35.4
WP_023852754.1\|43346_43646_-	DUF1974 domain-containing protein	NA	NA	NA	NA
WP_010929588.1\|43663_44614_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003815267.1\|45113_45749_+	hypothetical protein	NA	NA	NA	NA
WP_003815265.1\|45720_45957_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003815255.1\|46084_46978_+	membrane protein	NA	NA	NA	NA
WP_010929590.1\|48147_49395_+	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_003817748.1\|49391_50006_+	methionine biosynthesis protein MetW	NA	NA	NA	NA
WP_010929591.1\|50141_51092_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_029443813.1\|51134_52391_+	muropeptide transporter	NA	NA	NA	NA
WP_010929592.1\|53622_54357_-	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_019247224.1\|54362_54953_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.2e-20	33.6
WP_003817737.1\|54977_55667_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_023852650.1\|55663_56425_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_010929594.1\|56504_57404_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005012808.1\|57497_58448_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010929595.1\|59248_60475_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_010929596.1\|60474_60894_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010929597.1\|61077_62019_-	hypothetical protein	NA	NA	NA	NA
WP_010929598.1\|62442_63279_-	hypothetical protein	NA	NA	NA	NA
WP_010929599.1\|63473_64055_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_019248465.1\|64067_64385_-	Rieske 2Fe-2S domain-containing protein	NA	NA	NA	NA
WP_029443770.1\|64488_65547_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_019247832.1\|65581_66853_-	TRAP transporter large permease	NA	NA	NA	NA
WP_010929603.1\|67482_68664_-	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_005012808.1\|69085_70036_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

107426 : 175248

Bacillus_phage(22.22%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010929626.1\|107426_108377_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_010929627.1\|109276_110470_+	cystathionine beta-lyase	NA	NA	NA	NA
WP_010929628.1\|110551_111181_-	thiol:disulfide interchange protein DsbA/DsbL	NA	NA	NA	NA
WP_010927242.1\|111242_111926_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_023853376.1\|111935_113618_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_003815933.1\|113905_114253_+	DUF1840 domain-containing protein	NA	NA	NA	NA
WP_003815930.1\|114343_114661_+	hypothetical protein	NA	NA	NA	NA
WP_010931363.1\|114943_115960_+\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_003815929.1\|116035_116836_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_003815927.1\|116832_117708_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_010929633.1\|117718_119011_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010929634.1\|119053_120094_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.0e-22	33.7
WP_010929635.1\|120199_121021_-	phosphodiesterase	NA	NA	NA	NA
WP_005012067.1\|121121_122072_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_014905488.1\|122169_123075_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.8e-21	31.7
WP_003815918.1\|123071_123905_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_010929637.1\|124741_125752_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_019247800.1\|125748_126138_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_010929638.1\|127031_128285_+	amidase	NA	NA	NA	NA
WP_010929639.1\|128375_130076_-	2-isopropylmalate synthase	NA	NA	NA	NA
WP_010929640.1\|130502_131150_-	hypothetical protein	NA	NA	NA	NA
WP_023853393.1\|131148_132588_+	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_003815905.1\|132680_132983_+	bacterioferritin-associated ferredoxin	NA	NA	NA	NA
WP_010929512.1\|133010_133889_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005012067.1\|135155_136106_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_155120810.1\|136092_136236_-	hypothetical protein	NA	NA	NA	NA
WP_003815155.1\|136524_138033_-	threonine ammonia-lyase, biosynthetic	NA	NA	NA	NA
WP_019247146.1\|138779_142742_+	FAD/FMN-binding oxidoreductase	NA	NA	NA	NA
WP_010929644.1\|142794_143577_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010929645.1\|143664_144888_-	CoA transferase	NA	NA	NA	NA
WP_010929646.1\|144871_145804_-	alpha/beta hydrolase fold domain-containing protein	NA	NA	NA	NA
WP_003817676.1\|145809_146622_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_033446330.1\|147934_148858_-	hypothetical protein	NA	NA	NA	NA
WP_003815135.1\|149024_149807_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_010929648.1\|150573_151554_-	biotin-dependent carboxyltransferase	NA	NA	NA	NA
WP_010929649.1\|151550_152279_-	5-oxoprolinase subunit PxpB	NA	NA	NA	NA
WP_003815126.1\|152303_152735_-	VOC family protein	NA	NA	NA	NA
WP_010929650.1\|152836_153712_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010929651.1\|153762_154983_-	phosphoglycerate dehydrogenase	A0A1V0SBV6	Catovirus	3.2e-91	42.6
WP_010929652.1\|155065_155527_-	DUF411 domain-containing protein	NA	NA	NA	NA
WP_010929653.1\|155632_157030_-	heavy metal sensor histidine kinase	NA	NA	NA	NA
WP_010929654.1\|157026_157704_-	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	1.5e-29	35.2
WP_010929655.1\|157759_159070_-	phosphate regulon sensor histidine kinase PhoR	A0A1V0SGX0	Hokovirus	6.2e-16	25.5
WP_003815113.1\|159081_159780_-	phosphate regulon transcriptional regulatory protein PhoB	W8CYM9	Bacillus_phage	8.6e-33	37.1
WP_003815111.1\|159943_160720_+	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_010929656.1\|160885_161908_+	Tim44 domain-containing protein	NA	NA	NA	NA
WP_023853232.1\|162136_162772_+	SCP-2 sterol transfer family protein	NA	NA	NA	NA
WP_010929658.1\|162768_164331_+	ubiquinone biosynthesis regulatory protein kinase UbiB	A0A2N9QVT9	Dishui_lake_phycodnavirus	1.0e-33	28.7
WP_005015810.1\|164889_165840_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010929659.1\|167283_168186_-	YgcG family protein	NA	NA	NA	NA
WP_003815889.1\|168163_168793_-	LemA family protein	NA	NA	NA	NA
WP_029443820.1\|169123_170506_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.3e-42	29.5
WP_010929661.1\|170539_171169_+	LysE family transporter	NA	NA	NA	NA
WP_003815895.1\|171217_172825_+	peptide chain release factor 3	A0A2K9L6L3	Tupanvirus	9.3e-14	37.8
WP_010929663.1\|172849_173533_+	hypothetical protein	NA	NA	NA	NA
WP_003815898.1\|173614_174091_-	bacterioferritin	NA	NA	NA	NA
WP_077068973.1\|174131_174311_+	hypothetical protein	NA	NA	NA	NA
WP_010929591.1\|174297_175248_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

215658 : 266517

uncultured_Caudovirales_phage(33.33%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033455792.1\|215658_218454_-\|protease	serine protease autotransporter SphB1	NA	NA	NA	NA
WP_010929690.1\|219047_221990_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_010929689.1\|222061_222781_+	7-cyano-7-deazaguanine synthase QueC	A0A0A0RPC6	Escherichia_phage	8.0e-50	43.9
WP_010929688.1\|222819_223368_-	N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	1.2e-21	41.7
WP_010929687.1\|223522_224422_+	virginiamycin B lyase	NA	NA	NA	NA
WP_005012808.1\|224446_225397_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_127013037.1\|225383_225584_-	hypothetical protein	NA	NA	NA	NA
WP_003818947.1\|225615_226311_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_019247308.1\|226327_227740_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_010929684.1\|227852_229283_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_010929683.1\|229324_231238_-	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_010929682.1\|231556_232123_+	preprotein translocase subunit SecD	NA	NA	NA	NA
WP_010929681.1\|232213_233215_+	HindIII family type II restriction endonuclease	NA	NA	NA	NA
WP_005012067.1\|233329_234280_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010927663.1\|234366_235317_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_010930742.1\|235313_236264_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_153302767.1\|236250_236424_-	hypothetical protein	NA	NA	NA	NA
WP_010929700.1\|236362_237160_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_003814363.1\|238109_238520_+	4-carboxymuconolactone decarboxylase	NA	NA	NA	NA
WP_003814358.1\|239541_240285_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003814356.1\|240328_241372_-	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_003814355.1\|241542_243645_+	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_003814351.1\|245055_246012_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010929701.1\|246030_246522_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_010929702.1\|246518_247874_-	polynucleotide adenylyltransferase PcnB	A0A1B1IVF3	uncultured_Mediterranean_phage	3.4e-25	36.8
WP_010929703.1\|247874_248573_-	HAD-IB family hydrolase	NA	NA	NA	NA
WP_010929704.1\|248569_249271_-	DnaA regulatory inactivator Hda	NA	NA	NA	NA
WP_003814339.1\|249523_250573_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	5.6e-68	43.6
WP_003814337.1\|250678_251620_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_010929705.1\|251616_253506_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	3.3e-79	32.8
WP_003814332.1\|253592_254231_+	membrane protein	NA	NA	NA	NA
WP_019247543.1\|254373_255759_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4JCM7	uncultured_Caudovirales_phage	4.5e-17	30.3
WP_010929706.1\|255689_256226_-\|tRNA	bifunctional alanine racemase/tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_010929707.1\|256377_257769_+	class II fumarate hydratase	NA	NA	NA	NA
WP_010929708.1\|257785_258766_-	AEC family transporter	NA	NA	NA	NA
WP_003814324.1\|258901_259885_+	tripartite tricarboxylate transporter substrate binding protein BugE	NA	NA	NA	NA
WP_010929709.1\|259949_260849_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003814321.1\|260955_262710_+	gamma-glutamyltransferase	NA	NA	NA	NA
WP_010929710.1\|262717_263842_-	CoA transferase	NA	NA	NA	NA
WP_010929711.1\|263855_264836_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_005012067.1\|265566_266517_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

277133 : 303012

Pithovirus(33.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|277133_278084_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010929718.1\|278360_278522_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_010929719.1\|278529_278670_+	hypothetical protein	NA	NA	NA	NA
WP_003815821.1\|279188_279638_-\|protease	ClpXP protease specificity-enhancing factor	NA	NA	NA	NA
WP_003815819.1\|279647_280259_-	stringent starvation protein A	NA	NA	NA	NA
WP_019247426.1\|280417_281272_-	cytochrome c1	NA	NA	NA	NA
WP_003815816.1\|281291_282674_-	cytochrome bc complex cytochrome b subunit	NA	NA	NA	NA
WP_003815815.1\|282738_283380_-	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_010929721.1\|283519_283978_+	large conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_010927226.1\|284002_284779_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_014906092.1\|284832_285969_+\|protease	trypsin-like serine protease	W5SAB9	Pithovirus	1.2e-07	31.2
WP_005015810.1\|285965_286916_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003807705.1\|287013_287640_-	FMN-binding negative transcriptional regulator	NA	NA	NA	NA
WP_003807706.1\|287662_288589_-	glyoxylate/hydroxypyruvate reductase A	NA	NA	NA	NA
WP_003819100.1\|288597_290184_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010929723.1\|290180_291185_-	alpha/beta hydrolase	A0A2L2DMU8	Acanthamoeba_polyphaga_mimivirus	7.5e-30	31.5
WP_003807710.1\|291384_292245_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010929724.1\|292276_293278_-	2-isopropylmalate synthase	NA	NA	NA	NA
WP_003819104.1\|293348_294158_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003819105.1\|294235_296095_+	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_010929725.1\|296223_297426_-	MFS transporter	NA	NA	NA	NA
WP_004566082.1\|297539_298421_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004566083.1\|299923_300484_-	5'-3'-deoxyribonucleotidase	A0A1E1EUN3	Acanthamoeba_castellanii_mimivirus	3.2e-14	30.8
WP_005013747.1\|300543_301494_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_154299516.1\|301480_301639_-	hypothetical protein	NA	NA	NA	NA
WP_111735998.1\|301685_301973_-	hypothetical protein	NA	NA	NA	NA
WP_010929591.1\|302061_303012_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

390847 : 448356

Orpheovirus(14.29%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|390847_391798_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_154219862.1\|391784_391952_-	hypothetical protein	NA	NA	NA	NA
WP_010927231.1\|391934_392852_+	reductase	NA	NA	NA	NA
WP_003815842.1\|392848_393097_+	glutaredoxin family protein	NA	NA	NA	NA
WP_003815840.1\|393093_394299_+	CoA transferase	NA	NA	NA	NA
WP_014486045.1\|394371_395367_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_014486046.1\|395389_396610_-	CoA transferase	NA	NA	NA	NA
WP_014486047.1\|396606_397251_-	hypothetical protein	NA	NA	NA	NA
WP_019248476.1\|398981_399791_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_014906040.1\|400008_401049_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	6.1e-59	42.5
WP_023994705.1\|401017_401161_+	hypothetical protein	NA	NA	NA	NA
WP_014486049.1\|401147_402131_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_014486050.1\|402057_402759_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_014486051.1\|402807_403578_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_003819219.1\|403574_404816_-	CoA transferase	NA	NA	NA	NA
WP_014486052.1\|404920_406627_-	thiamine pyrophosphate-requiring protein	NA	NA	NA	NA
WP_014486053.1\|406623_407520_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_014486054.1\|407560_409150_-	sulfurtransferase	NA	NA	NA	NA
WP_003807867.1\|409199_410192_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003807865.1\|410260_410860_-	hypothetical protein	NA	NA	NA	NA
WP_076879611.1\|411320_412298_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010929577.1\|412376_413327_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_047122777.1\|413415_414330_+	DMT family transporter	NA	NA	NA	NA
WP_010929782.1\|414326_414986_+	LysE family translocator	NA	NA	NA	NA
WP_003814709.1\|415075_415999_+	alpha/beta fold hydrolase	A0A1C9C5K3	Heterosigma_akashiwo_virus	4.8e-07	27.2
WP_010929783.1\|416004_416460_-	multidrug/biocide efflux PACE transporter	NA	NA	NA	NA
WP_010929784.1\|416456_417560_-	ChbG/HpnK family deacetylase	NA	NA	NA	NA
WP_157734664.1\|417515_417788_+	hypothetical protein	NA	NA	NA	NA
WP_010927086.1\|417747_419367_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_003814720.1\|419363_420422_-	glycosyltransferase family 2 protein	I1TED8	Salmonella_phage	2.8e-59	40.5
WP_033446199.1\|420551_421046_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_022997984.1\|421138_422116_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010929785.1\|422311_423517_+	sodium/glutamate symporter	NA	NA	NA	NA
WP_010929786.1\|423513_425025_+	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_003814726.1\|425040_426354_-	short-chain fatty acid transporter	NA	NA	NA	NA
WP_003814728.1\|426544_426724_-	hypothetical protein	NA	NA	NA	NA
WP_003814730.1\|427133_427868_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.4e-41	43.8
WP_010929577.1\|430312_431263_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_019247421.1\|431394_431793_-	GTP-binding protein	E4ZFJ7	Streptococcus_phage	9.0e-19	44.3
WP_003814701.1\|432203_432674_-	universal stress protein	NA	NA	NA	NA
WP_003820700.1\|432762_433107_-	TIGR01244 family phosphatase	NA	NA	NA	NA
WP_010929788.1\|433206_434607_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_010929789.1\|436395_436914_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	2.1e-12	38.9
WP_003814694.1\|437024_437780_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	2.9e-42	40.8
WP_003814691.1\|437975_439208_+	CoA transferase	NA	NA	NA	NA
WP_010929791.1\|439200_439986_+	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_003814685.1\|440052_441024_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003814681.1\|441034_442012_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_019247419.1\|442137_443310_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_010929793.1\|443336_444365_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_003814674.1\|444430_445624_+	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
WP_005012067.1\|447405_448356_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

590408 : 651600

uncultured_Mediterranean_phage(40.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005013747.1\|590408_591359_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_033446133.1\|591834_592725_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_010931496.1\|592721_593543_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_019247235.1\|593743_594235_+	CYTH domain-containing protein	NA	NA	NA	NA
WP_019247236.1\|594253_595327_+	CHAD domain-containing protein	NA	NA	NA	NA
WP_023853086.1\|595373_596477_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_003808577.1\|596552_597173_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_003808574.1\|597193_597703_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	1.2e-28	42.1
WP_003808570.1\|597757_598009_+	YfhL family 4Fe-4S dicluster ferredoxin	A0A1B1IWY9	uncultured_Mediterranean_phage	1.6e-18	53.4
WP_010931494.1\|598072_599206_+	benzoate/H(+) symporter BenE family transporter	NA	NA	NA	NA
WP_003808567.1\|599213_599600_-	hypothetical protein	NA	NA	NA	NA
WP_010931493.1\|599596_602116_-	AsmA family protein	NA	NA	NA	NA
WP_003808563.1\|602544_602883_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003808562.1\|602879_603386_+	SRPBCC family protein	NA	NA	NA	NA
WP_010931492.1\|603447_604248_-	hypothetical protein	NA	NA	NA	NA
WP_010931491.1\|604358_605300_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010931490.1\|605393_606929_-	M81 family metallopeptidase	NA	NA	NA	NA
WP_010931489.1\|608608_610459_-	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-17	29.2
WP_003808549.1\|610462_611296_-	ABC transporter permease	NA	NA	NA	NA
WP_010931488.1\|611295_612237_-	ABC transporter permease	NA	NA	NA	NA
WP_003808546.1\|612488_613484_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010931486.1\|613601_615890_+	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_003808542.1\|616196_617105_+	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_010931485.1\|617159_618125_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_062810229.1\|618199_619861_+	thiamine pyrophosphate-binding protein	NA	NA	NA	NA
WP_023853074.1\|619857_620643_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_005012067.1\|620791_621742_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003814152.1\|622440_622824_+	membrane protein	NA	NA	NA	NA
WP_010927005.1\|622881_623484_+	DUF2946 family protein	NA	NA	NA	NA
WP_003820995.1\|623501_623903_-	DoxX family protein	NA	NA	NA	NA
WP_003814158.1\|624036_624930_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010931481.1\|624926_625508_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003814165.1\|626302_627037_+	arginyltransferase	NA	NA	NA	NA
WP_010931480.1\|627077_628127_+	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_003814172.1\|628274_628853_-	TIGR01841 family phasin	NA	NA	NA	NA
WP_010931479.1\|629239_630217_+	tripartite tricarboxylate transporter substrate binding protein BugD	NA	NA	NA	NA
WP_010931478.1\|630310_634705_-	dermonecrotic toxin	NA	NA	NA	NA
WP_003814178.1\|634905_635754_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_010931477.1\|635912_636725_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_005015810.1\|636780_637731_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_154219861.1\|637717_637882_-	hypothetical protein	NA	NA	NA	NA
WP_010931453.1\|637829_638630_-	EI24 domain-containing protein	NA	NA	NA	NA
WP_003814185.1\|638691_639075_+	thioredoxin family protein	NA	NA	NA	NA
WP_010931454.1\|639086_640520_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.5e-52	34.4
WP_003814188.1\|640726_641056_-	AzlD domain-containing protein	NA	NA	NA	NA
WP_003814191.1\|641058_641727_-	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_010931456.1\|641990_642911_+	branched-chain amino acid transaminase	NA	NA	NA	NA
WP_003814195.1\|642957_643170_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_010931457.1\|643192_643615_+	hypothetical protein	NA	NA	NA	NA
WP_010931458.1\|643631_644732_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_010931459.1\|644828_646346_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_003814203.1\|646421_647261_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.1e-66	48.9
WP_003814205.1\|647282_648164_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_003814206.1\|648245_649340_-	porin	NA	NA	NA	NA
WP_076879617.1\|649633_650584_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_041166340.1\|650658_651600_+\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

656918 : 703114

uncultured_Caudovirales_phage(17.39%)

terminase,transposase,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003814219.1\|656918_657950_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_003814221.1\|657990_658230_+	DNA-binding protein	NA	NA	NA	NA
WP_010931464.1\|658299_659889_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	8.7e-65	47.2
WP_010931465.1\|659888_660437_+	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
WP_003814226.1\|660517_661090_+	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_010927008.1\|661108_662020_-	complex I NDUFA9 subunit family protein	NA	NA	NA	NA
WP_003814230.1\|662093_663062_-	threo-3-hydroxy-L-aspartate ammonia-lyase	NA	NA	NA	NA
WP_010931466.1\|663184_664258_+	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	2.3e-08	25.7
WP_010931467.1\|664262_666083_-	DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	3.1e-74	35.3
WP_033446132.1\|667197_667533_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_003819076.1\|667666_668317_+	carbonic anhydrase	NA	NA	NA	NA
WP_010931468.1\|668338_669757_-	amidase	NA	NA	NA	NA
WP_019248554.1\|669826_670582_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_019247734.1\|670550_671309_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_010931471.1\|671319_672201_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_010931472.1\|672217_672925_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	8.2e-07	25.4
WP_010931473.1\|672927_673686_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	4.4e-14	24.4
WP_010931474.1\|673895_675638_+	nitrite/sulfite reductase	NA	NA	NA	NA
WP_010925795.1\|675630_676155_+	DUF934 domain-containing protein	NA	NA	NA	NA
WP_010931475.1\|676194_676989_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_019248926.1\|677156_678230_+	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|678328_679279_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931452.1\|679530_679743_-	hypothetical protein	NA	NA	NA	NA
WP_010931451.1\|679808_680420_-	S24 family peptidase	NA	NA	NA	NA
WP_010931450.1\|680899_681220_-	hypothetical protein	NA	NA	NA	NA
WP_010931449.1\|681212_681911_-	membrane protein	NA	NA	NA	NA
WP_023853183.1\|681925_682147_-	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|682164_683115_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931448.1\|683790_684240_+\|terminase	terminase	C7U0W1	Enterobacteria_phage	5.2e-39	61.5
WP_010931447.1\|684226_685504_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	2.4e-150	64.7
WP_010931446.1\|685506_686925_+	DUF4055 domain-containing protein	R9TF43	Synechococcus_phage	2.2e-99	42.1
WP_010931445.1\|686953_688009_+	hypothetical protein	A0A0H5BBX3	Pseudomonas_phage	2.6e-97	50.6
WP_010931444.1\|688014_688257_+	hypothetical protein	A0A0H5AUE5	Pseudomonas_phage	5.6e-16	53.2
WP_010931443.1\|688379_688982_+	hypothetical protein	R9TF81	Synechococcus_phage	7.9e-27	43.6
WP_005012808.1\|689410_690361_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_023853024.1\|690378_691026_+	hypothetical protein	R9TJ64	Synechococcus_phage	2.7e-65	71.1
WP_010931442.1\|691035_691287_+	hypothetical protein	NA	NA	NA	NA
WP_019247789.1\|691349_691832_+	hypothetical protein	A0A2H4JE38	uncultured_Caudovirales_phage	1.8e-13	37.1
WP_010931440.1\|691833_692034_+	hypothetical protein	NA	NA	NA	NA
WP_010931439.1\|692033_692429_+	hypothetical protein	A0A2D2W284	Stenotrophomonas_phage	7.8e-07	35.0
WP_010931438.1\|692425_692824_+	hypothetical protein	I6PCW1	Cronobacter_phage	4.2e-16	38.0
WP_010931437.1\|692820_693243_+	DUF4128 domain-containing protein	NA	NA	NA	NA
WP_010931436.1\|693250_693751_+	HNH endonuclease	A0A1I9SEX5	Klebsiella_phage	4.4e-31	45.1
WP_010931435.1\|694005_694524_+	hypothetical protein	A0A1S5R1H0	Pseudomonas_phage	5.4e-24	38.3
WP_003813412.1\|694533_694863_+	hypothetical protein	A0A2H4J121	uncultured_Caudovirales_phage	2.9e-15	44.0
WP_010931434.1\|694880_695171_+	DUF1799 domain-containing protein	A0A2H4JBP7	uncultured_Caudovirales_phage	3.7e-14	45.2
WP_010931433.1\|695196_697809_+\|tail	phage tail tape measure protein	A0A2H4J107	uncultured_Caudovirales_phage	4.9e-105	38.6
WP_010931432.1\|697818_698178_+	hypothetical protein	NA	NA	NA	NA
WP_010931431.1\|698245_698779_+	DUF1833 family protein	A5A3Q9	Burkholderia_phage	1.1e-40	46.9
WP_010931430.1\|698775_699165_+	C40 family peptidase	A0A0G3EYJ9	Achromobacter_phage	3.0e-35	50.0
WP_010931429.1\|699157_703114_+	DUF1983 domain-containing protein	A0A0B5A1N2	Achromobacter_phage	3.9e-215	40.8

DBSCAN-SWA_8

720303 : 779355

Streptococcus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012808.1\|720303_721254_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003814416.1\|723532_724621_+	spore maturation protein	NA	NA	NA	NA
WP_003814419.1\|724623_726066_-	pyruvate kinase	NA	NA	NA	NA
WP_010931414.1\|726170_727316_+	glycerate kinase	W6LM47	Streptococcus_phage	1.7e-41	42.2
WP_010931413.1\|727347_728145_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_010931412.1\|728169_729729_-	chaperone SurA	NA	NA	NA	NA
WP_010931411.1\|729725_732098_-	LPS-assembly protein LptD	NA	NA	NA	NA
WP_010931410.1\|732207_733311_+	phosphotransferase	NA	NA	NA	NA
WP_010931409.1\|733310_734003_+	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_003814436.1\|734146_734848_+	membrane protein	NA	NA	NA	NA
WP_003814437.1\|734832_735210_-	4a-hydroxytetrahydrobiopterin dehydratase	NA	NA	NA	NA
WP_005012067.1\|735941_736892_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_023852750.1\|736878_737022_-	hypothetical protein	NA	NA	NA	NA
WP_003814441.1\|737051_737924_-	oxaloacetate decarboxylase	NA	NA	NA	NA
WP_003814443.1\|738264_738483_+	DUF1059 domain-containing protein	NA	NA	NA	NA
WP_019247242.1\|738522_739902_-	aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_010929976.1\|739943_741341_-	amidase family protein	NA	NA	NA	NA
WP_010927038.1\|741380_743033_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.0e-16	30.8
WP_010929977.1\|743036_743921_-	ABC transporter permease	NA	NA	NA	NA
WP_010929978.1\|743920_744862_-	ABC transporter permease	NA	NA	NA	NA
WP_010929979.1\|744940_746560_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010929980.1\|746726_747542_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_003814459.1\|747609_748179_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_005013747.1\|748179_749130_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003814461.1\|749784_750882_+	carboxynorspermidine decarboxylase	NA	NA	NA	NA
WP_003814462.1\|750915_752181_+	saccharopine dehydrogenase family protein	NA	NA	NA	NA
WP_010929982.1\|753531_754122_+	polyisoprenoid-binding protein	NA	NA	NA	NA
WP_010929983.1\|754137_756582_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_003814467.1\|756701_757673_-	FecR family protein	NA	NA	NA	NA
WP_023852739.1\|757804_758329_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_005012067.1\|758288_759239_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010929984.1\|759459_761655_-	DUF1156 domain-containing protein	NA	NA	NA	NA
WP_020699729.1\|761727_762135_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_077068980.1\|762082_762271_+	hypothetical protein	NA	NA	NA	NA
WP_005012808.1\|762257_763208_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003807452.1\|763323_763767_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010925762.1\|763829_764624_+	response regulator transcription factor	NA	NA	NA	NA
WP_003807457.1\|764789_765926_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	5.8e-63	44.8
WP_003807459.1\|765996_767130_-	GTPase ObgE	NA	NA	NA	NA
WP_003807460.1\|767279_767540_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_003807462.1\|767573_767885_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_010929987.1\|768309_769458_+	fumarylacetoacetate hydrolase	NA	NA	NA	NA
WP_010929988.1\|769572_770538_+	octaprenyl diphosphate synthase	NA	NA	NA	NA
WP_010929989.1\|770806_771673_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010929990.1\|771803_773852_+	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
WP_010929991.1\|773869_775867_+	hydantoinase B/oxoprolinase family protein	NA	NA	NA	NA
WP_010929992.1\|775901_777239_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_023853308.1\|777501_779355_+\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

885795 : 953771

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023994644.1\|885795_886812_-\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_003813988.1\|887008_887992_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010930019.1\|889590_890979_-	MmgE/PrpD family protein	NA	NA	NA	NA
WP_003813991.1\|891009_891999_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003813992.1\|892109_893342_-	methylaspartate ammonia-lyase	NA	NA	NA	NA
WP_003813993.1\|893623_894424_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_010930018.1\|894446_896678_-	BCCT family transporter	NA	NA	NA	NA
WP_010930017.1\|897465_897912_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_003813996.1\|897933_898680_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_003813997.1\|898823_899801_-	NAD(P)H-quinone oxidoreductase	NA	NA	NA	NA
WP_010930016.1\|900434_901046_+	PIN domain-containing protein	K4HZX4	Acidithiobacillus_phage	3.3e-12	32.5
WP_003813999.1\|901039_902257_-	threonine ammonia-lyase	NA	NA	NA	NA
WP_005013747.1\|902397_903348_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003814000.1\|903344_904064_-	lipoprotein	NA	NA	NA	NA
WP_003821234.1\|904184_906344_-	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_003814002.1\|906434_906704_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_005019401.1\|906792_906999_-	hypothetical protein	NA	NA	NA	NA
WP_003814003.1\|906997_907525_+	lipoprotein	NA	NA	NA	NA
WP_003814004.1\|907543_908323_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_010930015.1\|908490_909507_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_003814006.1\|909579_910071_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_003814007.1\|910081_911797_-	acetolactate synthase 3 catalytic subunit	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	3.1e-60	30.3
WP_005012067.1\|912960_913911_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_019248601.1\|913907_915758_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.3e-27	26.4
WP_010930052.1\|916138_916798_+	thiopurine S-methyltransferase	NA	NA	NA	NA
WP_010930053.1\|916885_917038_+	vir-repressed protein	NA	NA	NA	NA
WP_003809770.1\|917146_917314_+	hypothetical protein	NA	NA	NA	NA
WP_010930054.1\|917325_918006_-	DUF3313 domain-containing protein	NA	NA	NA	NA
WP_010930055.1\|918287_919004_+	flagellar brake protein	NA	NA	NA	NA
WP_010930056.1\|919018_920320_-	phospholipase	NA	NA	NA	NA
WP_029444137.1\|922464_925353_+	HD domain-containing protein	NA	NA	NA	NA
WP_010930057.1\|925576_926929_+	MmgE/PrpD family protein	NA	NA	NA	NA
WP_004568140.1\|926957_927479_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_003819989.1\|927475_928930_+	carboxylase	NA	NA	NA	NA
WP_023852826.1\|928964_929213_+	hypothetical protein	NA	NA	NA	NA
WP_019247557.1\|929318_930194_+	amidohydrolase	NA	NA	NA	NA
WP_010930060.1\|930219_931275_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930061.1\|931287_932079_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010930062.1\|932111_933482_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_023995501.1\|934534_934672_+	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|934658_935609_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930064.1\|935661_935883_+	hypothetical protein	NA	NA	NA	NA
WP_003810832.1\|936042_936255_+	hypothetical protein	NA	NA	NA	NA
WP_003810835.1\|936374_937493_+	mannose-6-phosphate isomerase	NA	NA	NA	NA
WP_003810837.1\|937589_937805_+	hypothetical protein	NA	NA	NA	NA
WP_003810839.1\|937998_938250_+	hypothetical protein	NA	NA	NA	NA
WP_010930066.1\|938362_939313_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003810840.1\|939309_939693_-	Rieske 2Fe-2S domain-containing protein	NA	NA	NA	NA
WP_010930067.1\|939747_941565_-	ABC transporter ATP-binding protein/permease	W8CYL7	Bacillus_phage	5.7e-44	27.9
WP_010930068.1\|941711_942539_+	oxidoreductase	A0A2H4PQR8	Staphylococcus_phage	1.7e-67	47.4
WP_010930069.1\|942584_943565_+	aldo/keto reductase	NA	NA	NA	NA
WP_003810850.1\|943561_943774_-	hypothetical protein	NA	NA	NA	NA
WP_003810851.1\|943770_944952_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_019248496.1\|945115_945850_+	serine/threonine protein phosphatase	A0A2H4J0P0	uncultured_Caudovirales_phage	1.9e-62	49.2
WP_010930071.1\|945851_948464_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_003810859.1\|948599_950513_-	S9 family peptidase	NA	NA	NA	NA
WP_010930072.1\|951128_951539_-	PaaI family thioesterase	NA	NA	NA	NA
WP_003810865.1\|951636_952722_+	DNA polymerase IV	NA	NA	NA	NA
WP_005012067.1\|952820_953771_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_10

976949 : 1047216

Streptococcus_phage(14.29%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|976949_977900_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_014486062.1\|977980_978892_+	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	8.0e-47	38.8
WP_010930108.1\|978952_980098_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_003821521.1\|980117_981032_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	9.8e-45	34.7
WP_010930110.1\|981103_981853_+	electron transfer flavoprotein subunit beta/FixA family protein	NA	NA	NA	NA
WP_010930111.1\|981852_982782_+	electron transfer flavoprotein subunit alpha	NA	NA	NA	NA
WP_003821527.1\|983025_984852_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_003813333.1\|984934_985576_+	peroxiredoxin	NA	NA	NA	NA
WP_003821528.1\|985765_986800_+	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010930112.1\|988636_989701_+	sulfate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.8e-24	30.3
WP_010930113.1\|990498_991407_+	sulfate adenylyltransferase subunit CysD	NA	NA	NA	NA
WP_023852693.1\|992894_994169_+	PA0069 family radical SAM protein	NA	NA	NA	NA
WP_023852686.1\|994322_994703_+	hypothetical protein	NA	NA	NA	NA
WP_014905652.1\|994710_995583_-	EamA family transporter	NA	NA	NA	NA
WP_003813315.1\|995888_996269_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_003813314.1\|996479_997205_+	CoA pyrophosphatase	NA	NA	NA	NA
WP_005012067.1\|997300_998251_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930118.1\|998355_999405_+	NADP(H)-dependent aldo-keto reductase	NA	NA	NA	NA
WP_010929632.1\|999542_1000559_-\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_010926548.1\|1002067_1002640_-	chorismate lyase	NA	NA	NA	NA
WP_010930119.1\|1002699_1003431_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_029443805.1\|1003482_1004400_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010930121.1\|1005207_1008387_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_014486063.1\|1008383_1009766_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_010930123.1\|1009835_1010087_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_023853098.1\|1010232_1010883_-	SCO family protein	NA	NA	NA	NA
WP_019248379.1\|1011033_1013148_-	M3 family metallopeptidase	NA	NA	NA	NA
WP_003811948.1\|1013223_1014075_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.1e-33	39.8
WP_010930126.1\|1014071_1014698_-	response regulator transcription factor	NA	NA	NA	NA
WP_003817147.1\|1014694_1016449_-	PAS domain S-box protein	NA	NA	NA	NA
WP_010930127.1\|1016741_1019447_+	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_010930128.1\|1019459_1021121_+	dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_010930129.1\|1021133_1022924_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.4e-39	25.2
WP_003817151.1\|1023145_1024321_-	FliC/FljB family flagellin	NA	NA	NA	NA
WP_010929584.1\|1024363_1025314_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_010930130.1\|1025412_1026153_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_010930131.1\|1026347_1028384_+	transketolase	NA	NA	NA	NA
WP_010930132.1\|1028401_1029412_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_010930133.1\|1029529_1030723_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_010930134.1\|1030752_1031526_-	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_010930135.1\|1031522_1032713_-	acetate kinase	NA	NA	NA	NA
WP_003809454.1\|1032738_1033677_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_010930136.1\|1033673_1036022_-	DUF3141 domain-containing protein	NA	NA	NA	NA
WP_029443834.1\|1036176_1036884_-	glutathione transferase	NA	NA	NA	NA
WP_023853531.1\|1036921_1038055_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_023994624.1\|1038147_1038300_-	hypothetical protein	NA	NA	NA	NA
WP_010930138.1\|1038331_1038880_-	diguanylate cyclase	NA	NA	NA	NA
WP_003819814.1\|1038898_1039384_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_010930139.1\|1039561_1040500_+	DnaJ domain-containing protein	A0A0P0YMJ9	Yellowstone_lake_phycodnavirus	5.6e-11	24.1
WP_003809467.1\|1040502_1040820_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_019247197.1\|1040865_1041810_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_010930141.1\|1043490_1044141_+	molybdopterin adenylyltransferase	NA	NA	NA	NA
WP_003809479.1\|1044194_1044530_+	hypothetical protein	NA	NA	NA	NA
WP_010930142.1\|1044526_1045387_+	M23 family metallopeptidase	A0A292GJG6	Xanthomonas_phage	2.6e-15	36.1
WP_003819817.1\|1045403_1045685_-	hypothetical protein	NA	NA	NA	NA
WP_003809486.1\|1045758_1046022_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_005012067.1\|1046265_1047216_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

1059434 : 1116917

uncultured_Mediterranean_phage(37.5%)

holin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010931363.1\|1059434_1060451_-\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_003819773.1\|1061281_1062289_+	aldo/keto reductase	NA	NA	NA	NA
WP_014486064.1\|1062285_1063929_-	apolipoprotein N-acyltransferase	NA	NA	NA	NA
WP_023995116.1\|1063925_1064828_-	CBS domain-containing protein	NA	NA	NA	NA
WP_003809396.1\|1064953_1065427_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_010930151.1\|1065416_1066439_-	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	8.7e-50	45.4
WP_015041211.1\|1066435_1067863_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_010931363.1\|1068800_1069817_-\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_003809411.1\|1070149_1071085_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	3.0e-41	35.5
WP_010930154.1\|1071134_1073015_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_003809416.1\|1073081_1073426_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	1.0e-10	40.4
WP_010930155.1\|1073570_1074707_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.9e-85	44.4
WP_023853534.1\|1074703_1075777_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_003809423.1\|1075934_1077371_+	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
WP_010930157.1\|1077461_1078103_+	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_077068988.1\|1081330_1081510_+	hypothetical protein	NA	NA	NA	NA
WP_005012808.1\|1081496_1082447_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930160.1\|1083649_1085071_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_003809431.1\|1085334_1086051_+	hypothetical protein	NA	NA	NA	NA
WP_003809432.1\|1086135_1086453_+	DUF883 domain-containing protein	NA	NA	NA	NA
WP_003819794.1\|1086493_1086907_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_010930161.1\|1086908_1087268_+	hypothetical protein	NA	NA	NA	NA
WP_023853525.1\|1087310_1088855_-	4-hydroxy-3-polyprenylbenzoate decarboxylase	NA	NA	NA	NA
WP_010930163.1\|1088938_1089769_+	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_010930164.1\|1089803_1090958_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_010930165.1\|1091000_1091873_+	hypothetical protein	NA	NA	NA	NA
WP_014486065.1\|1091989_1094278_+	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_003809441.1\|1095484_1095949_+	barstar family protein	NA	NA	NA	NA
WP_005013747.1\|1095975_1096926_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930167.1\|1097293_1098070_-	phosphate ABC transporter ATP-binding protein PstB	G9BWD6	Planktothrix_phage	4.3e-17	28.7
WP_003809638.1\|1098114_1098972_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_010930169.1\|1098993_1100010_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_014486066.1\|1100144_1101185_-	phosphate ABC transporter substrate-binding protein PstS	M4QHS4	Cyanophage	2.1e-51	40.2
WP_010930171.1\|1101379_1103461_-	polyphosphate kinase 1	NA	NA	NA	NA
WP_010930172.1\|1103696_1105190_+	exopolyphosphatase	NA	NA	NA	NA
WP_003809629.1\|1105420_1106215_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003819875.1\|1106435_1107794_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_010930173.1\|1107790_1108633_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	3.2e-26	32.5
WP_010930174.1\|1108651_1110538_-	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	M4QMW8	Micromonas_pusilla_virus	1.4e-109	41.5
WP_010930175.1\|1110775_1111408_-	RlmE family RNA methyltransferase	NA	NA	NA	NA
WP_003809618.1\|1111426_1112029_+	YhbY family RNA-binding protein	NA	NA	NA	NA
WP_023995509.1\|1112032_1112194_+	hypothetical protein	NA	NA	NA	NA
WP_010929591.1\|1112180_1113131_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930177.1\|1113933_1114734_-	hypothetical protein	NA	NA	NA	NA
WP_003812707.1\|1114777_1115764_-	homoserine kinase	NA	NA	NA	NA
WP_010930178.1\|1115903_1116917_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA

DBSCAN-SWA_12

1153214 : 1218783

Erysipelothrix_phage(33.33%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023853221.1\|1153214_1155011_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_019248398.1\|1155010_1155979_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003816844.1\|1156048_1156894_+	PHP domain-containing protein	NA	NA	NA	NA
WP_003812405.1\|1156961_1157516_+	transcription elongation factor GreB	NA	NA	NA	NA
WP_010930198.1\|1157562_1158513_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930199.1\|1158611_1159244_-	fimbrial protein	NA	NA	NA	NA
WP_010930200.1\|1159408_1161691_-	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_010930201.1\|1161845_1164542_-	alpha-ketoglutarate dehydrogenase	NA	NA	NA	NA
WP_010930202.1\|1164667_1165156_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_003813631.1\|1167566_1170437_+	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_010930204.1\|1170482_1171697_+	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_003813626.1\|1171926_1173354_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.1e-41	28.1
WP_019248962.1\|1173394_1174543_+	cell division protein ZapE	NA	NA	NA	NA
WP_010930206.1\|1174555_1175314_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_003813621.1\|1175401_1176304_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005012067.1\|1176300_1177251_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930207.1\|1177380_1178364_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003813618.1\|1178418_1179141_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930211.1\|1180617_1181973_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_010930212.1\|1182053_1184429_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_010930213.1\|1184593_1186669_+	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	2.4e-75	30.0
WP_003813594.1\|1186730_1187531_-	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_010930214.1\|1187632_1188595_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_019247742.1\|1188582_1189338_+	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_010930216.1\|1189445_1191083_+	class I poly(R)-hydroxyalkanoic acid synthase	NA	NA	NA	NA
WP_003813586.1\|1191150_1191888_+	acetoacetyl-CoA reductase	NA	NA	NA	NA
WP_003813585.1\|1191990_1192566_+	polyhydroxyalkanoate synthesis repressor PhaR	NA	NA	NA	NA
WP_010930217.1\|1192738_1193275_+	membrane protein	NA	NA	NA	NA
WP_003813580.1\|1193277_1193622_+	cupredoxin domain-containing protein	NA	NA	NA	NA
WP_010930218.1\|1193637_1194483_+	membrane protein	NA	NA	NA	NA
WP_003821443.1\|1194521_1195901_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_003813574.1\|1195978_1196860_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_010929956.1\|1196957_1197908_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_003811632.1\|1197904_1198315_-	VOC family protein	NA	NA	NA	NA
WP_010930219.1\|1198422_1199277_-	amidohydrolase family protein	NA	NA	NA	NA
WP_003811636.1\|1199269_1200232_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010930220.1\|1200277_1201402_-	mandelate racemase/muconate lactonizing enzyme family protein	Q6A202	Oenococcus_phage	1.5e-31	28.3
WP_010930221.1\|1201513_1202386_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010930222.1\|1202510_1203290_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930223.1\|1203443_1204865_+	MFS transporter	NA	NA	NA	NA
WP_010930224.1\|1205299_1206997_+	sodium:solute symporter family protein	NA	NA	NA	NA
WP_003811651.1\|1207025_1207148_+	membrane protein	NA	NA	NA	NA
WP_010930225.1\|1207223_1208165_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_010930226.1\|1208491_1209238_+	aldolase	NA	NA	NA	NA
WP_033446252.1\|1209245_1210172_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010930228.1\|1210293_1211211_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_003811660.1\|1211250_1212204_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003811662.1\|1212228_1212807_+	amino acid synthesis family protein	NA	NA	NA	NA
WP_010930229.1\|1214480_1215089_+	hypothetical protein	NA	NA	NA	NA
WP_010930230.1\|1215166_1215520_-	NirD/YgiW/YdeI family stress tolerance protein	NA	NA	NA	NA
WP_010930231.1\|1215603_1216593_-	succinylglutamate desuccinylase	NA	NA	NA	NA
WP_076879566.1\|1216795_1217746_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010927663.1\|1217832_1218783_+\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_13

1417552 : 1469705

Salmonella_phage(25.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005013747.1\|1417552_1418503_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_154219858.1\|1418489_1418657_-	hypothetical protein	NA	NA	NA	NA
WP_003814065.1\|1418669_1419023_+	cytochrome c	NA	NA	NA	NA
WP_003814063.1\|1419035_1419398_+	cytochrome c	NA	NA	NA	NA
WP_003814061.1\|1419439_1419865_-	DUF1841 family protein	NA	NA	NA	NA
WP_003814059.1\|1420067_1421324_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.2e-11	64.8
WP_003814057.1\|1421522_1422503_+	hypothetical protein	NA	NA	NA	NA
WP_005015028.1\|1422652_1423894_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_005013747.1\|1423992_1424943_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003814052.1\|1424951_1425647_-	two-component system response regulator KdpE	NA	NA	NA	NA
WP_003814050.1\|1428468_1429068_-	potassium-transporting ATPase subunit KdpC	NA	NA	NA	NA
WP_010930950.1\|1429078_1431244_-	potassium-transporting ATPase subunit KdpB	M1HBF8	Paramecium_bursaria_Chlorella_virus	1.2e-24	27.1
WP_010930949.1\|1431267_1433052_-	potassium-transporting ATPase subunit KdpA	NA	NA	NA	NA
WP_017685545.1\|1433051_1433141_-	K(+)-transporting ATPase subunit F	NA	NA	NA	NA
WP_003814042.1\|1433835_1434108_+	DUF4212 domain-containing protein	NA	NA	NA	NA
WP_003814040.1\|1434107_1436174_+	cation acetate symporter	NA	NA	NA	NA
WP_010929577.1\|1436170_1437121_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_005012067.1\|1437219_1438170_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_005015014.1\|1438285_1438618_-	multidrug transporter	NA	NA	NA	NA
WP_010929073.1\|1438614_1439301_-	hypothetical protein	NA	NA	NA	NA
WP_010930948.1\|1439287_1440247_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	3.1e-57	40.2
WP_003814032.1\|1440288_1442649_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	7.6e-81	48.0
WP_010930946.1\|1442648_1443281_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_003814028.1\|1443343_1444723_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.6e-75	38.9
WP_010930944.1\|1444769_1446125_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.6e-83	47.5
WP_003814025.1\|1446403_1446652_+	hypothetical protein	NA	NA	NA	NA
WP_003814024.1\|1446839_1447157_-	virulence factor	NA	NA	NA	NA
WP_003814023.1\|1447429_1447945_-	hypothetical protein	T1SAR8	Salmonella_phage	5.1e-06	44.6
WP_003814022.1\|1448038_1448200_+	hypothetical protein	NA	NA	NA	NA
WP_003814021.1\|1448215_1448971_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_019247690.1\|1449309_1449516_+	hypothetical protein	NA	NA	NA	NA
WP_003814020.1\|1449523_1450183_-	NAAT family transporter	NA	NA	NA	NA
WP_010930941.1\|1450477_1452682_-	TonB-dependent alcaligin siderophore receptor FauA	NA	NA	NA	NA
WP_010930940.1\|1452792_1454016_-	alcaligin siderophore export MFS transporter Bcr	S4TR35	Salmonella_phage	9.8e-24	29.4
WP_003814017.1\|1454138_1455113_-	alcaligin siderophore biosynthesis transcriptional regulator AlcR	NA	NA	NA	NA
WP_005013753.1\|1455180_1456374_-	alcaligin siderophore biosynthesis protein AlcE	NA	NA	NA	NA
WP_003814016.1\|1456388_1457189_-	alcaligin siderophore biosynthesis protein AlcD	NA	NA	NA	NA
WP_010930939.1\|1457185_1459042_-	alcaligin siderophore biosynthesis protein AlcC	NA	NA	NA	NA
WP_003814014.1\|1459038_1459644_-	alcaligin siderophore biosynthesis protein AlcB	NA	NA	NA	NA
WP_003814013.1\|1459662_1461048_-	alcaligin siderophore biosynthesis protein AlcA	NA	NA	NA	NA
WP_003814012.1\|1461773_1463000_+	transporter	NA	NA	NA	NA
WP_003814011.1\|1463088_1463871_+	3-hydroxybutyrate dehydrogenase	NA	NA	NA	NA
WP_005012067.1\|1463969_1464920_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003814010.1\|1464946_1465720_+	peroxide stress protein YaaA	NA	NA	NA	NA
WP_003814009.1\|1465731_1466973_+	MFS transporter	NA	NA	NA	NA
WP_076879548.1\|1468754_1469705_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_14

1515387 : 1581714

Streptococcus_virus(11.11%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|1515387_1516338_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_023994932.1\|1516344_1517457_-	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_010930419.1\|1518143_1519346_+	MFS transporter	NA	NA	NA	NA
WP_010930420.1\|1519549_1522210_+	hypothetical protein	NA	NA	NA	NA
WP_010930421.1\|1522222_1525627_+	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_023995689.1\|1526294_1528520_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	1.2e-43	38.5
WP_010930423.1\|1528566_1528893_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_010930424.1\|1528943_1529552_+	recombination protein RecR	NA	NA	NA	NA
WP_005013747.1\|1529649_1530600_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930425.1\|1530669_1531434_-	hypothetical protein	NA	NA	NA	NA
WP_010930426.1\|1531430_1532030_-	hypothetical protein	NA	NA	NA	NA
WP_003820094.1\|1532133_1532979_-	putative membrane protein	A0A1I9SA48	Rhodococcus_phage	7.0e-37	35.3
WP_010928449.1\|1533044_1533671_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_005012067.1\|1533667_1534618_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_077068977.1\|1534604_1534793_-	hypothetical protein	NA	NA	NA	NA
WP_010930428.1\|1534716_1535838_-	DUF1513 domain-containing protein	NA	NA	NA	NA
WP_019248041.1\|1535818_1536820_-	imelysin family protein	NA	NA	NA	NA
WP_019247498.1\|1536925_1538437_-	c-type cytochrome	NA	NA	NA	NA
WP_023853587.1\|1538433_1539738_-	imelysin	NA	NA	NA	NA
WP_010930431.1\|1539849_1540410_-	membrane protein	NA	NA	NA	NA
WP_010930432.1\|1540677_1541232_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.7e-15	32.0
WP_010930433.1\|1541687_1541903_-	dodecin domain-containing protein	NA	NA	NA	NA
WP_033446228.1\|1542157_1544755_+	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	1.5e-21	22.6
WP_010930435.1\|1544751_1545939_+	cupin	NA	NA	NA	NA
WP_010930436.1\|1546596_1547211_+	serotype 3 fimbrial subunit	NA	NA	NA	NA
WP_010930437.1\|1547299_1548427_-	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_033446216.1\|1548438_1549344_-	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_023994753.1\|1550094_1550250_+	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|1550236_1551187_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930439.1\|1551368_1552121_+	glutamine ABC transporter substrate-binding protein GlnH	NA	NA	NA	NA
WP_003811112.1\|1552189_1552849_+	glutamine ABC transporter permease GlnP	NA	NA	NA	NA
WP_003811113.1\|1552845_1553574_+	glutamine ABC transporter ATP-binding protein GlnQ	G9BWD6	Planktothrix_phage	3.3e-35	39.3
WP_010930440.1\|1553586_1555866_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	5.9e-06	32.1
WP_010930441.1\|1555890_1556094_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_003811129.1\|1556135_1556783_-	guanylate kinase	A0A218KC48	Bacillus_phage	3.1e-13	33.9
WP_010930443.1\|1556903_1557821_-	c-type cytochrome	NA	NA	NA	NA
WP_010930444.1\|1557817_1558531_-	c-type cytochrome	NA	NA	NA	NA
WP_003811135.1\|1558768_1559539_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_003811137.1\|1559543_1560143_-	C40 family peptidase	A0A0A8WF62	Clostridium_phage	1.4e-20	41.6
WP_003811138.1\|1560387_1561878_+	AMP nucleosidase	NA	NA	NA	NA
WP_010926696.1\|1561936_1562221_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010928840.1\|1562217_1562346_-	hypothetical protein	NA	NA	NA	NA
WP_010930445.1\|1562358_1562514_-	hypothetical protein	NA	NA	NA	NA
WP_003811148.1\|1562786_1563713_-	YicC family protein	NA	NA	NA	NA
WP_003811149.1\|1563849_1564590_+	ribonuclease PH	NA	NA	NA	NA
WP_010930446.1\|1564756_1566133_-	MmgE/PrpD family protein	NA	NA	NA	NA
WP_003811152.1\|1566314_1567220_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010930448.1\|1568871_1570674_-	EAL domain-containing protein	NA	NA	NA	NA
WP_003811159.1\|1570791_1571442_+	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	NA	NA	NA	NA
WP_005012808.1\|1571540_1572491_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930450.1\|1572512_1573733_+	oxygen-independent coproporphyrinogen III oxidase-like protein	NA	NA	NA	NA
WP_003811164.1\|1573918_1575331_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_003811167.1\|1575394_1576462_+	PAS domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	1.1e-05	23.5
WP_003811170.1\|1576458_1577949_+	nitrogen regulation protein NR(I)	NA	NA	NA	NA
WP_010930452.1\|1577958_1578903_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003811176.1\|1579062_1579761_+	pirin family protein	NA	NA	NA	NA
WP_010930453.1\|1579838_1580744_+	pirin family protein	NA	NA	NA	NA
WP_005012067.1\|1580763_1581714_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_15

1617663 : 1673254

Brazilian_cedratvirus(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005013747.1\|1617663_1618614_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930486.1\|1618672_1619446_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_014486074.1\|1619438_1620995_+	LTA synthase family protein	NA	NA	NA	NA
WP_005013747.1\|1620991_1621942_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_154219857.1\|1621928_1622084_-	hypothetical protein	NA	NA	NA	NA
WP_003810741.1\|1623268_1623871_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003810743.1\|1624110_1624812_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_003816696.1\|1624805_1625588_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	2.0e-09	25.8
WP_005012808.1\|1625772_1626723_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_153302777.1\|1626709_1626871_-	hypothetical protein	NA	NA	NA	NA
WP_010930483.1\|1626821_1627559_-	TerC family protein	A0A0S4KZH7	Pseudomonas_phage	4.1e-41	46.6
WP_010926609.1\|1627748_1628507_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930482.1\|1628553_1629543_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010930481.1\|1629720_1630689_-	transporter	NA	NA	NA	NA
WP_010930480.1\|1632228_1633197_+	AAA family ATPase	NA	NA	NA	NA
WP_010930479.1\|1633205_1634147_+	DUF58 domain-containing protein	NA	NA	NA	NA
WP_010930478.1\|1634620_1635631_+	VWA domain-containing protein	NA	NA	NA	NA
WP_010930477.1\|1635621_1637136_+	VWA domain-containing protein	NA	NA	NA	NA
WP_010930476.1\|1637132_1638479_+	hypothetical protein	NA	NA	NA	NA
WP_010930475.1\|1638481_1639516_+	haloacid dehalogenase-like hydrolase	NA	NA	NA	NA
WP_023852967.1\|1639565_1641191_+	arylsulfatase	A0A2P0VMN7	Tetraselmis_virus	2.0e-149	52.2
WP_005012067.1\|1641743_1642694_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930487.1\|1642798_1643746_+	hypothetical protein	NA	NA	NA	NA
WP_019247865.1\|1643799_1645614_-	sensor histidine kinase	NA	NA	NA	NA
WP_010930489.1\|1645606_1646281_-	response regulator transcription factor	NA	NA	NA	NA
WP_023995112.1\|1646410_1649485_+	autotransporter SphB2	NA	NA	NA	NA
WP_019247905.1\|1649498_1649798_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010930492.1\|1650112_1650736_-	glutathione S-transferase	NA	NA	NA	NA
WP_010930493.1\|1650979_1651849_+	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_010930494.1\|1651826_1652771_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010930495.1\|1652856_1653828_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010930496.1\|1653895_1654669_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930497.1\|1654665_1655862_-	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_010930498.1\|1655892_1656843_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_010930499.1\|1657064_1657754_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930500.1\|1657818_1658574_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930501.1\|1658625_1659618_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010930502.1\|1659627_1660581_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003811538.1\|1660696_1661659_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_019249376.1\|1663060_1663489_+	hypothetical protein	NA	NA	NA	NA
WP_005013747.1\|1663485_1664436_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930503.1\|1664729_1665452_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	1.3e-87	68.2
WP_010930504.1\|1665890_1667078_-	MFS transporter	NA	NA	NA	NA
WP_019249653.1\|1667081_1667462_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010930506.1\|1669181_1670153_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010930507.1\|1670166_1670880_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_010930508.1\|1670884_1671802_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003811452.1\|1671908_1672205_+	hypothetical protein	NA	NA	NA	NA
WP_010929588.1\|1672303_1673254_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_16

1831020 : 1890290

Klosneuvirus(40.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005013747.1\|1831020_1831971_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930573.1\|1832095_1832905_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_153302779.1\|1832960_1833119_+	hypothetical protein	NA	NA	NA	NA
WP_010929577.1\|1833105_1834056_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930574.1\|1835329_1836547_+	four-carbon acid sugar kinase family protein	NA	NA	NA	NA
WP_003818670.1\|1837603_1838506_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_010930576.1\|1838582_1839455_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_003818672.1\|1839585_1839954_+	aspartate 1-decarboxylase	NA	NA	NA	NA
WP_010930577.1\|1840011_1841058_+	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_010930578.1\|1841253_1842510_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_003810623.1\|1842514_1843852_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_003818676.1\|1844001_1844958_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_019247555.1\|1845060_1845993_-	acyclic terpene utilization AtuA family protein	NA	NA	NA	NA
WP_019247554.1\|1846108_1846429_+	hypothetical protein	NA	NA	NA	NA
WP_010930580.1\|1846430_1846781_+	hypothetical protein	NA	NA	NA	NA
WP_010930581.1\|1846828_1848403_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003810637.1\|1848455_1849400_+	ABC transporter permease	NA	NA	NA	NA
WP_010930582.1\|1849417_1850248_+	ABC transporter permease	NA	NA	NA	NA
WP_010930583.1\|1850240_1851875_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.2e-18	32.7
WP_010930584.1\|1851871_1853227_+	amidase	NA	NA	NA	NA
WP_010930585.1\|1854133_1855711_+	lipoprotein	NA	NA	NA	NA
WP_010930586.1\|1855714_1856989_+	type 4b pilus protein PilO2	NA	NA	NA	NA
WP_010930587.1\|1857086_1857461_+	hypothetical protein	NA	NA	NA	NA
WP_010930588.1\|1859176_1860310_+	general secretion pathway protein	NA	NA	NA	NA
WP_003810661.1\|1860347_1860953_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_010930589.1\|1860949_1861768_+	hypothetical protein	NA	NA	NA	NA
WP_010930590.1\|1861839_1864464_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.7e-81	39.4
WP_004568544.1\|1864450_1864705_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_010930591.1\|1864771_1865353_-	hypothetical protein	NA	NA	NA	NA
WP_010926757.1\|1865656_1865917_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_014905757.1\|1866082_1866706_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_003816734.1\|1866705_1867479_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_010930593.1\|1867475_1868684_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_010930594.1\|1868709_1869183_-	RidA family protein	NA	NA	NA	NA
WP_010930048.1\|1869256_1870207_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_076879566.1\|1870305_1871256_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930796.1\|1871354_1872704_-	two-component sensor histidine kinase	NA	NA	NA	NA
WP_023852900.1\|1873469_1874225_+	MipA/OmpV family protein	NA	NA	NA	NA
WP_010930794.1\|1874317_1877200_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	3.7e-138	37.1
WP_003810689.1\|1877522_1877948_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.1e-21	43.2
WP_004568542.1\|1877975_1879124_+	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_003810693.1\|1879120_1879627_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010930793.1\|1879633_1880929_+	flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
WP_010930792.1\|1880969_1882274_+\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_010930791.1\|1882275_1882914_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_003810701.1\|1882916_1884077_+	outer membrane protein assembly factor BamB	NA	NA	NA	NA
WP_003810703.1\|1884103_1885459_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_010930790.1\|1885462_1886533_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	2.5e-15	25.7
WP_003810707.1\|1886671_1886908_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_010930789.1\|1886995_1888102_+	GTPase HflX	NA	NA	NA	NA
WP_010930788.1\|1888067_1889372_+\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_010930787.1\|1889390_1890290_+\|protease	protease modulator HflC	NA	NA	NA	NA

DBSCAN-SWA_17

1900530 : 1944852

Staphylococcus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005013747.1\|1900530_1901481_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_005013747.1\|1901579_1902530_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_076879573.1\|1902516_1902717_-	hypothetical protein	NA	NA	NA	NA
WP_010930782.1\|1902729_1903815_+	AI-2E family transporter	NA	NA	NA	NA
WP_003810400.1\|1903830_1904592_-	ABC transporter permease	NA	NA	NA	NA
WP_010930781.1\|1904588_1905512_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-23	33.6
WP_019248115.1\|1905610_1906135_-	N-acetyltransferase	NA	NA	NA	NA
WP_010930779.1\|1906143_1906887_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_010930778.1\|1906982_1907222_-	membrane protein	NA	NA	NA	NA
WP_010930777.1\|1907235_1907388_-	lipoprotein	NA	NA	NA	NA
WP_010930776.1\|1907473_1908964_-	cytochrome c oxidase accessory protein CcoG	NA	NA	NA	NA
WP_010930775.1\|1909055_1909994_-	cytochrome-c oxidase, cbb3-type subunit III	NA	NA	NA	NA
WP_003818560.1\|1909990_1910167_-	cytochrome oxidase	NA	NA	NA	NA
WP_003810383.1\|1910169_1910832_-	cytochrome-c oxidase, cbb3-type subunit II	NA	NA	NA	NA
WP_003810379.1\|1912453_1912597_-	cbb3-type cytochrome oxidase assembly protein CcoS	NA	NA	NA	NA
WP_010930774.1\|1912593_1913568_-	membrane protein	NA	NA	NA	NA
WP_153302783.1\|1913604_1913748_+	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|1913734_1914685_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930773.1\|1914681_1915956_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	9.6e-14	28.9
WP_076879572.1\|1916053_1917253_+	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_010930771.1\|1917249_1917903_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_010930770.1\|1917899_1919336_+	dethiobiotin synthase	NA	NA	NA	NA
WP_010930769.1\|1919323_1919683_+	CidA/LrgA family protein	NA	NA	NA	NA
WP_005012067.1\|1920655_1921606_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930768.1\|1922650_1924516_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_010930767.1\|1924773_1926294_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_003816959.1\|1926381_1927032_-	flavodoxin family protein	NA	NA	NA	NA
WP_010930766.1\|1927980_1929276_+	DUF445 domain-containing protein	NA	NA	NA	NA
WP_010930765.1\|1929297_1930182_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010930764.1\|1930280_1931156_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_003816964.1\|1931145_1931502_-	DUF1428 domain-containing protein	NA	NA	NA	NA
WP_076879571.1\|1931575_1932607_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003812228.1\|1932736_1932916_-	DUF3008 family protein	NA	NA	NA	NA
WP_029443822.1\|1933013_1933538_+	DUF302 domain-containing protein	NA	NA	NA	NA
WP_010930761.1\|1933548_1934385_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003816971.1\|1934497_1934869_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010930760.1\|1934865_1935417_+	SRPBCC family protein	NA	NA	NA	NA
WP_003816975.1\|1935432_1937124_-	STAS domain-containing protein	A0A2H4J153	uncultured_Caudovirales_phage	5.0e-42	27.3
WP_003816977.1\|1937172_1937853_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_014905663.1\|1938100_1938565_-	hypothetical protein	NA	NA	NA	NA
WP_010930758.1\|1938734_1939664_+	ZIP family metal transporter	NA	NA	NA	NA
WP_019247659.1\|1939676_1940324_-	hypothetical protein	NA	NA	NA	NA
WP_023997035.1\|1940397_1942215_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.3e-37	27.4
WP_005012067.1\|1942298_1943249_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_154299520.1\|1943753_1943915_+	hypothetical protein	NA	NA	NA	NA
WP_010929577.1\|1943901_1944852_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_18

2170524 : 2220176

Synechococcus_phage(14.29%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|2170524_2171475_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_076879626.1\|2171573_2173568_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.4e-21	33.3
WP_010930543.1\|2173627_2174593_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_010930542.1\|2174582_2177444_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	1.0e-71	25.5
WP_010930541.1\|2177446_2177953_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_010930540.1\|2178057_2179266_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	3.8e-36	30.0
WP_033446178.1\|2179267_2180206_-	membrane protein	NA	NA	NA	NA
WP_010930538.1\|2180367_2180841_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_005012808.1\|2180837_2181788_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_076879558.1\|2181774_2181954_-	hypothetical protein	NA	NA	NA	NA
WP_004566334.1\|2181898_2182339_-	DUF937 domain-containing protein	NA	NA	NA	NA
WP_010930537.1\|2182467_2183697_-	lytic murein transglycosylase	NA	NA	NA	NA
WP_004566336.1\|2183735_2184557_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_029443743.1\|2184610_2185762_+	N-acetyltransferase	NA	NA	NA	NA
WP_010930535.1\|2185853_2186342_-	DUF1854 domain-containing protein	NA	NA	NA	NA
WP_010930534.1\|2188868_2191442_+	cyanophycin synthetase	NA	NA	NA	NA
WP_010930533.1\|2191512_2194086_+	cyanophycin synthetase	NA	NA	NA	NA
WP_003813568.1\|2194351_2194552_+	CsbD family protein	NA	NA	NA	NA
WP_003813570.1\|2194583_2194745_+	DUF1328 domain-containing protein	NA	NA	NA	NA
WP_003813572.1\|2194802_2195141_+	BON domain-containing protein	NA	NA	NA	NA
WP_005012067.1\|2195289_2196240_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_077274081.1\|2196337_2197057_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.4e-22	36.6
WP_029443816.1\|2197133_2197682_+	arylesterase	NA	NA	NA	NA
WP_019247881.1\|2197663_2199679_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_004568486.1\|2199861_2200611_+	glycerophosphodiester phosphodiesterase	A0A2H4PGQ5	Escherichia_phage	1.5e-14	27.8
WP_003816518.1\|2200623_2201487_+	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_003816520.1\|2201490_2202906_-	dihydrolipoyl dehydrogenase	NA	NA	NA	NA
WP_010930530.1\|2203039_2203768_-	redoxin family protein	A0A1D8KSL1	Synechococcus_phage	9.6e-43	56.8
WP_003811035.1\|2203906_2204107_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_003816523.1\|2204282_2204681_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_003816525.1\|2204704_2206105_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	7.3e-31	26.5
WP_010930529.1\|2206223_2206976_-	hypothetical protein	NA	NA	NA	NA
WP_003816527.1\|2207264_2207942_-	hypothetical protein	NA	NA	NA	NA
WP_019248494.1\|2207968_2208748_-	3'-5' exonuclease	NA	NA	NA	NA
WP_003811022.1\|2208744_2209629_-	peptidoglycan DD-metalloendopeptidase family protein	A0A292GJG6	Xanthomonas_phage	4.6e-15	49.5
WP_077274094.1\|2209646_2210336_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.2e-32	46.9
WP_010930526.1\|2210410_2211169_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.4e-68	51.2
WP_003811015.1\|2211294_2211942_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_010929632.1\|2212209_2213226_+\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_010930524.1\|2213323_2214364_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	6.1e-91	51.3
WP_003811011.1\|2214498_2215791_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	1.7e-66	36.0
WP_003811007.1\|2217150_2217534_+	thioredoxin family protein	V9SJ74	Achromobacter_phage	8.1e-09	25.8
WP_010930523.1\|2217551_2218139_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	4.7e-16	35.8
WP_005012067.1\|2218176_2219127_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930048.1\|2219225_2220176_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_19

2638437 : 2709019

Planktothrix_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010930208.1\|2638437_2639388_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930310.1\|2640295_2641441_+	DUF3182 family protein	NA	NA	NA	NA
WP_010930309.1\|2641460_2642183_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_003811361.1\|2642299_2642479_+	hypothetical protein	NA	NA	NA	NA
WP_153302775.1\|2643480_2643636_-	hypothetical protein	NA	NA	NA	NA
WP_010930308.1\|2646296_2649638_+	maltose alpha-D-glucosyltransferase	NA	NA	NA	NA
WP_010930307.1\|2649634_2651830_+	1,4-alpha-glucan branching protein GlgB	NA	NA	NA	NA
WP_010930306.1\|2651834_2653955_+	glycogen debranching protein GlgX	NA	NA	NA	NA
WP_010930305.1\|2653951_2655706_+	malto-oligosyltrehalose trehalohydrolase	NA	NA	NA	NA
WP_010930304.1\|2657072_2659616_+	malto-oligosyltrehalose synthase	NA	NA	NA	NA
WP_010930303.1\|2662678_2663533_-	pyridoxine/pyridoxal/pyridoxamine kinase	NA	NA	NA	NA
WP_003811326.1\|2663529_2664345_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_010930302.1\|2664404_2665736_+	transcriptional regulator PtsJ	NA	NA	NA	NA
WP_003811324.1\|2665774_2666281_+	hypothetical protein	NA	NA	NA	NA
WP_019247534.1\|2666520_2666874_+	hypothetical protein	NA	NA	NA	NA
WP_003811322.1\|2666945_2667371_+	universal stress protein	NA	NA	NA	NA
WP_019247533.1\|2667403_2668291_+	aldo/keto reductase	NA	NA	NA	NA
WP_010930301.1\|2668293_2668617_-	hypothetical protein	NA	NA	NA	NA
WP_010930300.1\|2669853_2670258_+	DoxX family protein	NA	NA	NA	NA
WP_019247530.1\|2670439_2670871_+	BcpO-related WXXGXW repeat protein	NA	NA	NA	NA
WP_076879575.1\|2671140_2671623_+	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|2671609_2672560_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_005012067.1\|2672658_2673609_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003811316.1\|2673701_2674241_+	peroxiredoxin	NA	NA	NA	NA
WP_023852799.1\|2674347_2674692_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	3.0e-31	58.4
WP_010930298.1\|2674749_2676198_-	CoA transferase	NA	NA	NA	NA
WP_003811313.1\|2676385_2676721_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_010930297.1\|2678348_2679527_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_003811310.1\|2679609_2680110_+	glutathione peroxidase	Q6VZR0	Canarypox_virus	4.7e-25	38.4
WP_077274085.1\|2680135_2680921_+	thiol:disulfide oxidoreductase	NA	NA	NA	NA
WP_010930295.1\|2680932_2681397_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003811307.1\|2681393_2681687_+	hypothetical protein	NA	NA	NA	NA
WP_003811306.1\|2681683_2682460_+	lipoate--protein ligase family protein	NA	NA	NA	NA
WP_010930294.1\|2682488_2683316_+	DUF3298 domain-containing protein	NA	NA	NA	NA
WP_010930293.1\|2683441_2683912_+	hypothetical protein	NA	NA	NA	NA
WP_003811301.1\|2684038_2684932_+	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_010930292.1\|2684979_2686161_+	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_003811298.1\|2686173_2686989_-	exported protein	NA	NA	NA	NA
WP_010930291.1\|2687122_2687650_-	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_003811295.1\|2687646_2688144_-	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_003811293.1\|2688291_2688669_+	DUF423 domain-containing protein	NA	NA	NA	NA
WP_003811244.1\|2689938_2690550_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_010930290.1\|2690784_2691912_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010930289.1\|2692022_2693111_-	sn-glycerol-3-phosphate import ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	2.2e-19	31.2
WP_003811259.1\|2693163_2694015_-	sn-glycerol-3-phosphate ABC transporter permease UgpE	NA	NA	NA	NA
WP_003811262.1\|2694034_2694916_-	sn-glycerol-3-phosphate ABC transporter permease UgpA	NA	NA	NA	NA
WP_010930288.1\|2695092_2696406_-	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	NA	NA	NA	NA
WP_003811267.1\|2696616_2697450_+	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_010930287.1\|2697446_2698028_+	queuosine precursor transporter	A0A2I7SAW6	Vibrio_phage	9.4e-17	37.3
WP_124740682.1\|2698152_2698395_+	hypothetical protein	NA	NA	NA	NA
WP_005015810.1\|2698381_2699332_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010930286.1\|2699347_2700463_+	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003811272.1\|2700565_2701492_+	high-affinity branched-chain amino acid ABC transporter permease LivH	NA	NA	NA	NA
WP_010930285.1\|2701491_2702730_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_003811277.1\|2702726_2703494_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-14	26.4
WP_010930284.1\|2703494_2704196_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-17	30.4
WP_019247793.1\|2704277_2704724_-	glutamate racemase	NA	NA	NA	NA
WP_010930283.1\|2705613_2706252_+	glutathione S-transferase	NA	NA	NA	NA
WP_005012808.1\|2707019_2707970_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_005012808.1\|2708068_2709019_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_20

2839355 : 2912366

uncultured_Mediterranean_phage(22.22%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|2839355_2840306_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931085.1\|2840440_2841547_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_010931086.1\|2841557_2842655_+	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_010931087.1\|2842799_2844005_-	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_010931088.1\|2844011_2844533_-	molybdenum cofactor biosynthesis protein B	NA	NA	NA	NA
WP_010931089.1\|2844529_2845021_-	molybdenum cofactor biosynthesis protein MoaE	NA	NA	NA	NA
WP_003819740.1\|2845017_2845269_-	MoaD/ThiS family protein	NA	NA	NA	NA
WP_003819741.1\|2845249_2845735_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_010931090.1\|2845870_2849332_+	DUF748 domain-containing protein	NA	NA	NA	NA
WP_076879578.1\|2849328_2850234_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_010931092.1\|2850243_2850675_-	lipoprotein	NA	NA	NA	NA
WP_003809348.1\|2850921_2851425_+	peroxiredoxin	M1I839	Pelagibacter_phage	1.8e-24	44.1
WP_023995849.1\|2851436_2852903_+	MFS transporter	NA	NA	NA	NA
WP_010931095.1\|2852977_2853853_-	membrane protein	NA	NA	NA	NA
WP_023853546.1\|2853849_2854857_-	biotin synthase BioB	NA	NA	NA	NA
WP_010931097.1\|2855324_2855630_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_003819753.1\|2855720_2856311_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_010930525.1\|2856501_2857518_-\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_010931098.1\|2857709_2860046_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.2e-124	42.8
WP_003812014.1\|2860128_2860563_+	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_010931099.1\|2862654_2863449_-	N-formylglutamate deformylase	NA	NA	NA	NA
WP_010931100.1\|2863480_2864185_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_010931101.1\|2864259_2865060_-	SURF1 family protein	NA	NA	NA	NA
WP_003809276.1\|2865056_2865464_-	cytochrome o ubiquinol oxidase subunit IV	NA	NA	NA	NA
WP_003819722.1\|2865460_2866102_-	cytochrome o ubiquinol oxidase subunit III	NA	NA	NA	NA
WP_019247695.1\|2866094_2868116_-	cytochrome o ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_010931103.1\|2869355_2870687_+	MFS transporter	NA	NA	NA	NA
WP_005012067.1\|2870683_2871634_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931105.1\|2873339_2873606_-	accessory factor UbiK family protein	NA	NA	NA	NA
WP_003812839.1\|2874313_2874652_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_010931107.1\|2879204_2879807_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_010931108.1\|2879903_2881193_+	MFS transporter	NA	NA	NA	NA
WP_003812846.1\|2881250_2881982_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-12	31.0
WP_010931109.1\|2881978_2882782_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.9e-14	23.5
WP_003812851.1\|2882778_2883867_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_003820410.1\|2883863_2884793_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_003812857.1\|2884941_2886087_-	branched-chain amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010931110.1\|2887388_2891210_-	trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_010931111.1\|2891366_2892035_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_014905522.1\|2892039_2893713_-	MCE family protein	NA	NA	NA	NA
WP_003820402.1\|2893731_2895051_-	PqiA/YebS family transporter subunit	NA	NA	NA	NA
WP_023995053.1\|2895055_2897407_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	4.2e-164	41.9
WP_010931115.1\|2897426_2899595_-	penicillin-binding protein 1C	NA	NA	NA	NA
WP_010931116.1\|2899591_2904781_-	alpha-2-macroglobulin family protein	NA	NA	NA	NA
WP_003820400.1\|2904870_2905185_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.2e-10	43.8
WP_003812875.1\|2905412_2905658_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-20	76.6
WP_003820399.1\|2905752_2906271_+	hypothetical protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.1e-14	42.2
WP_010931117.1\|2906370_2907576_-	3-oxoadipyl-CoA thiolase	NA	NA	NA	NA
WP_019247560.1\|2907691_2909089_-	chloride channel protein	NA	NA	NA	NA
WP_010931119.1\|2909205_2909784_-	superoxide dismutase [Fe]	NA	NA	NA	NA
WP_010931120.1\|2909856_2911248_-	exodeoxyribonuclease VII large subunit	A0A1V0SD82	Indivirus	1.4e-29	32.0
WP_005012067.1\|2911415_2912366_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_21

2922012 : 2981762

Vibrio_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|2922012_2922963_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931130.1\|2925346_2926459_-	Ldh family oxidoreductase	NA	NA	NA	NA
WP_005012808.1\|2926515_2927466_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003813070.1\|2927673_2927895_-	YgdI/YgdR family lipoprotein	NA	NA	NA	NA
WP_010931131.1\|2928108_2929515_-	threonine synthase	NA	NA	NA	NA
WP_003813074.1\|2929511_2930816_-	homoserine dehydrogenase	NA	NA	NA	NA
WP_003813076.1\|2930812_2932120_-	alanine transaminase	NA	NA	NA	NA
WP_003813077.1\|2932216_2932669_+	Xcc1710-like domain-containing protein	NA	NA	NA	NA
WP_003813079.1\|2932671_2933136_+	peroxiredoxin	NA	NA	NA	NA
WP_023853657.1\|2933215_2934895_+	PhoH family protein	A0A2I7SAD7	Vibrio_phage	7.3e-70	36.7
WP_003813085.1\|2934999_2935977_+	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_010931134.1\|2936056_2937025_+	bile acid:sodium symporter	NA	NA	NA	NA
WP_003813089.1\|2937045_2938419_-	replicative DNA helicase	C7BGG1	Burkholderia_phage	4.0e-135	58.2
WP_003813091.1\|2938415_2939252_-	hypothetical protein	NA	NA	NA	NA
WP_010931135.1\|2939368_2939824_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_003813094.1\|2939839_2940112_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_003813095.1\|2940204_2940528_-	primosomal replication protein N	NA	NA	NA	NA
WP_010926331.1\|2940575_2940956_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_003813103.1\|2941175_2941973_-	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_010931136.1\|2942129_2943992_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_003820295.1\|2944041_2944953_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_003813109.1\|2944957_2945224_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_033446289.1\|2945310_2946141_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_010931138.1\|2946315_2947281_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003813114.1\|2947451_2948462_+	acyltransferase family protein	A0A0F6TJ51	Escherichia_coli_O157_typing_phage	3.6e-16	24.6
WP_076879579.1\|2948468_2949761_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_023996438.1\|2950694_2950853_-	hypothetical protein	NA	NA	NA	NA
WP_003814555.1\|2950903_2952376_-	magnesium transporter	NA	NA	NA	NA
WP_003814554.1\|2952386_2952797_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_010929220.1\|2952860_2953907_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_003814552.1\|2954013_2954892_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010931140.1\|2954905_2956102_-	amidohydrolase	NA	NA	NA	NA
WP_010931141.1\|2956163_2957855_+	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	9.4e-33	28.1
WP_005012067.1\|2957851_2958802_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_076879632.1\|2958788_2959034_-	hypothetical protein	NA	NA	NA	NA
WP_023852715.1\|2958922_2959819_-	inositol monophosphatase	NA	NA	NA	NA
WP_003814547.1\|2962096_2964322_+	glycoside hydrolase family 31 protein	NA	NA	NA	NA
WP_003814544.1\|2964486_2965575_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.7e-32	36.4
WP_019247918.1\|2965531_2966185_+	ABC transporter permease	NA	NA	NA	NA
WP_010931144.1\|2966232_2967030_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010930176.1\|2967561_2968512_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_023994659.1\|2968592_2969741_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_005012067.1\|2969797_2970748_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_076879633.1\|2970734_2970953_-	hypothetical protein	NA	NA	NA	NA
WP_003814535.1\|2970846_2971152_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003820797.1\|2971180_2971615_-	DUF126 domain-containing protein	NA	NA	NA	NA
WP_010931147.1\|2971616_2972861_-	DUF521 domain-containing protein	NA	NA	NA	NA
WP_003820799.1\|2972857_2973568_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_033446288.1\|2973582_2974494_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010931149.1\|2974856_2975261_+	hypothetical protein	NA	NA	NA	NA
WP_019247890.1\|2975257_2975716_+	hypothetical protein	NA	NA	NA	NA
WP_019247891.1\|2975722_2976631_+	hypothetical protein	NA	NA	NA	NA
WP_010931150.1\|2976627_2977494_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_003814524.1\|2977480_2978308_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_003820806.1\|2978318_2979446_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-23	32.3
WP_023852748.1\|2980523_2981762_+\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_22

2987742 : 3033129

Ostreococcus_lucimarinus_virus(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023852714.1\|2987742_2988693_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_010931155.1\|2988796_2989417_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003820818.1\|2989520_2990261_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_019248356.1\|2991395_2992520_-	hypothetical protein	NA	NA	NA	NA
WP_019247402.1\|2992565_2992934_-	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|2993175_2994126_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_019247492.1\|2995161_2995704_-	hypothetical protein	NA	NA	NA	NA
WP_124740747.1\|2995896_2996103_+	hypothetical protein	NA	NA	NA	NA
WP_005012067.1\|2996089_2997040_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_023997028.1\|2997036_2998002_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003815281.1\|2998071_2998908_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0P0BXC9	Ostreococcus_lucimarinus_virus	1.6e-33	33.3
WP_076879583.1\|2999384_3000530_+	porin	NA	NA	NA	NA
WP_005012067.1\|3000591_3001542_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931159.1\|3001734_3002517_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_010931160.1\|3002530_3003280_-	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	1.2e-11	26.4
WP_010931161.1\|3003307_3004654_-	MFS transporter	NA	NA	NA	NA
WP_010931162.1\|3004679_3005609_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003819549.1\|3005724_3006630_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010931163.1\|3006647_3007847_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_010931164.1\|3007919_3008612_-	HD domain-containing protein	A0A1D6Y7U0	Golden_Marseillevirus	4.7e-07	29.9
WP_010931165.1\|3008660_3011087_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.2e-86	33.8
WP_023853143.1\|3011131_3012082_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003809026.1\|3012298_3012667_-	DUF861 domain-containing protein	NA	NA	NA	NA
WP_003809025.1\|3012953_3013880_+	VOC family protein	NA	NA	NA	NA
WP_010931167.1\|3013923_3014934_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_010931168.1\|3014930_3015365_+	PaaI family thioesterase	NA	NA	NA	NA
WP_010931169.1\|3016490_3017279_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-33	40.0
WP_010931170.1\|3017288_3018071_+	ABC transporter permease	NA	NA	NA	NA
WP_010931171.1\|3018074_3019166_-	DUF2817 domain-containing protein	NA	NA	NA	NA
WP_010931172.1\|3019271_3020747_+	acyl--CoA ligase	Q75ZG1	Hepacivirus	3.0e-35	25.6
WP_010931173.1\|3020888_3021437_+	hypothetical protein	NA	NA	NA	NA
WP_003809010.1\|3021452_3021914_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_010931174.1\|3022014_3023004_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010931175.1\|3023302_3024004_+	riboflavin synthase	NA	NA	NA	NA
WP_010931176.1\|3024042_3025416_-	amidase	NA	NA	NA	NA
WP_023997744.1\|3025454_3026741_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_010931177.1\|3027627_3028530_+	transcriptional regulator GcvA	NA	NA	NA	NA
WP_010931178.1\|3028477_3029698_-	MFS transporter	NA	NA	NA	NA
WP_010931179.1\|3029694_3030204_-	nucleoside deaminase	NA	NA	NA	NA
WP_010926062.1\|3030193_3030889_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_010931181.1\|3030959_3031829_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_010930208.1\|3032178_3033129_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_23

3403436 : 3467267

Staphylococcus_phage(12.5%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005012067.1\|3403436_3404387_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_153302791.1\|3404373_3404550_-	hypothetical protein	NA	NA	NA	NA
WP_010931344.1\|3405153_3406248_-	CoA transferase	NA	NA	NA	NA
WP_019247312.1\|3406240_3407575_-	AMP-binding protein	NA	NA	NA	NA
WP_003808193.1\|3407528_3408212_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_024000003.1\|3408237_3409401_-	acyl-CoA dehydrogenase C-terminal domain protein	NA	NA	NA	NA
WP_004566224.1\|3409397_3410399_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_010931346.1\|3410398_3411271_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_010931347.1\|3411267_3412017_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.9e-09	27.8
WP_010931348.1\|3412013_3412805_-	ATP-binding cassette domain-containing protein	A0A1M7XV31	Cedratvirus	1.7e-08	29.4
WP_010931349.1\|3412801_3413941_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_033446332.1\|3414249_3415002_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_014486103.1\|3415035_3415818_+	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_010931351.1\|3415821_3416211_+	hypothetical protein	NA	NA	NA	NA
WP_010931352.1\|3417350_3418214_+	3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase	NA	NA	NA	NA
WP_010931353.1\|3418249_3419338_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_080501793.1\|3420270_3420684_-	hypothetical protein	NA	NA	NA	NA
WP_019247959.1\|3420637_3423616_+	hypothetical protein	NA	NA	NA	NA
WP_003818344.1\|3424542_3425421_+	fatty acid desaturase	NA	NA	NA	NA
WP_005013747.1\|3427369_3428320_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931354.1\|3428316_3428784_-	ribonuclease HI	J9Q745	Salmonella_phage	5.6e-36	50.7
WP_010931355.1\|3428826_3429597_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_010927090.1\|3429617_3430418_+	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_010931356.1\|3430428_3431838_+	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_003814739.1\|3431932_3432718_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_010931561.1\|3432957_3433974_+\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_003814742.1\|3434081_3434474_-	OsmC family protein	NA	NA	NA	NA
WP_010931357.1\|3434611_3435292_+	tellurite resistance TerB family protein	NA	NA	NA	NA
WP_010931358.1\|3435296_3436295_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_010930179.1\|3436363_3437314_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_003814239.1\|3438818_3439520_+	response regulator	W8CYM9	Bacillus_phage	5.6e-32	36.6
WP_010927010.1\|3439519_3440944_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_010931360.1\|3440960_3442016_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_010931361.1\|3442012_3443353_-	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_003820957.1\|3443468_3445232_+\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	5.0e-162	50.0
WP_010931362.1\|3445343_3446222_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_003814250.1\|3446334_3447150_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_003814252.1\|3447153_3447405_+	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_010929632.1\|3447489_3448506_-\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA
WP_003814254.1\|3448836_3449058_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_019247693.1\|3451418_3452336_-	DMT family transporter	NA	NA	NA	NA
WP_019247692.1\|3452833_3454042_-	ABC transporter permease	NA	NA	NA	NA
WP_010931365.1\|3454121_3455693_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003814275.1\|3455810_3456746_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_003814277.1\|3456934_3457879_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	8.4e-07	23.2
WP_003814281.1\|3457947_3458163_-	hypothetical protein	NA	NA	NA	NA
WP_003814283.1\|3458446_3464164_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.0e-195	39.5
WP_010931367.1\|3464169_3465297_+	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	3.8e-38	37.8
WP_003814287.1\|3465352_3465979_+	hypothetical protein	NA	NA	NA	NA
WP_010931363.1\|3466250_3467267_+\|transposase	IS110-like element IS1663 family transposase	NA	NA	NA	NA

DBSCAN-SWA_24

3471681 : 3590623

102

Acinetobacter_phage(22.22%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019247745.1\|3471681_3472554_-\|tRNA	tRNA threonylcarbamoyladenosine dehydratase	NA	NA	NA	NA
WP_003814298.1\|3472822_3474043_+	MFS transporter	NA	NA	NA	NA
WP_003814300.1\|3474039_3474699_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_003814302.1\|3474770_3475403_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_010931372.1\|3475432_3475951_+	flavin reductase family protein	NA	NA	NA	NA
WP_010931373.1\|3475961_3477071_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_003814312.1\|3477117_3477972_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_010931374.1\|3477973_3478876_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005012067.1\|3480098_3481049_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_023997720.1\|3482803_3483793_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931375.1\|3483968_3484757_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	5.1e-66	53.0
WP_003817833.1\|3484753_3485785_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	7.4e-73	42.7
WP_003815390.1\|3485803_3486367_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.1e-65	62.1
WP_010931376.1\|3486422_3487943_-	anthranilate synthase component I	S4VT78	Pandoravirus	9.0e-43	32.1
WP_010931377.1\|3488206_3488911_-	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_003815384.1\|3488918_3489656_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_003815381.1\|3489761_3490136_+	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_003815379.1\|3490178_3491468_+	murein transglycosylase A	NA	NA	NA	NA
WP_010931378.1\|3491464_3492634_+	UbiH/UbiF family hydroxylase	NA	NA	NA	NA
WP_010931379.1\|3492630_3493470_+	thiol:disulfide interchange protein DsbC	NA	NA	NA	NA
WP_010931380.1\|3493529_3494465_+	D-2-hydroxyacid dehydrogenase family protein	A0A1J0F959	Only_Syngen_Nebraska_virus	6.4e-15	27.7
WP_005012067.1\|3494477_3495428_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931381.1\|3495526_3496489_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	4.6e-93	64.5
WP_003817821.1\|3496520_3496880_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_010931382.1\|3497004_3497907_+	NAD(P)/FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	1.9e-08	24.0
WP_010931383.1\|3497908_3499681_-	M61 family metallopeptidase	NA	NA	NA	NA
WP_003815367.1\|3499715_3500492_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_023852617.1\|3501815_3502766_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_003815365.1\|3503617_3503938_+	ABC transporter permease	NA	NA	NA	NA
WP_003815364.1\|3504010_3504892_+	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_003815363.1\|3505008_3505251_+	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_010931385.1\|3505388_3505859_+	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_003815348.1\|3505871_3506411_+	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_010931386.1\|3506445_3507987_+	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_003817813.1\|3508085_3508991_+	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_010931387.1\|3509033_3510434_+	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_003815341.1\|3510443_3510866_+	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_010931388.1\|3511048_3511933_+	hypothetical protein	NA	NA	NA	NA
WP_010931389.1\|3512008_3513085_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_019247688.1\|3513391_3515494_+	primosomal protein N'	NA	NA	NA	NA
WP_010931391.1\|3515536_3517606_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	2.6e-101	37.3
WP_005012808.1\|3517704_3518655_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_010931392.1\|3518783_3519917_-	M20 family metallopeptidase	NA	NA	NA	NA
WP_010931393.1\|3519960_3520866_-	hydrolase	NA	NA	NA	NA
WP_023852622.1\|3520868_3522569_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-15	32.7
WP_010931394.1\|3522565_3523486_-	ABC transporter permease	NA	NA	NA	NA
WP_003817805.1\|3523493_3524471_-	ABC transporter permease	NA	NA	NA	NA
WP_010931395.1\|3524529_3525564_-	hypothetical protein	NA	NA	NA	NA
WP_003815317.1\|3527538_3527775_-	hypothetical protein	NA	NA	NA	NA
WP_023995266.1\|3527901_3528765_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_003815315.1\|3528853_3529675_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_003815313.1\|3529754_3530492_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_010931397.1\|3530488_3531481_-	nitronate monooxygenase	NA	NA	NA	NA
WP_003817794.1\|3531594_3532257_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_010931399.1\|3532301_3533450_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_010931400.1\|3535773_3536724_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_005013747.1\|3537199_3538150_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_101558015.1\|3538122_3539064_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_005013747.1\|3539162_3540113_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_029443756.1\|3540409_3540907_+	cupredoxin family protein	NA	NA	NA	NA
WP_010931403.1\|3540949_3542725_+	copper resistance system multicopper oxidase	NA	NA	NA	NA
WP_076879643.1\|3542771_3543599_+	copper resistance protein B	NA	NA	NA	NA
WP_019249391.1\|3543605_3544340_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_010931406.1\|3545509_3546304_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_003815296.1\|3546593_3547184_+	cysteine dioxygenase	NA	NA	NA	NA
WP_010931407.1\|3547217_3548546_-	amidase	NA	NA	NA	NA
WP_010931408.1\|3548620_3549766_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014905478.1\|3549877_3550876_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_033446233.1\|3550838_3551273_+	carbon monoxide dehydrogenase	NA	NA	NA	NA
WP_010929974.1\|3552789_3553674_+	DMT family transporter	NA	NA	NA	NA
WP_010929973.1\|3553670_3554876_-	cardiolipin synthase ClsB	NA	NA	NA	NA
WP_010929972.1\|3554872_3555733_-	endonuclease	NA	NA	NA	NA
WP_003807038.1\|3555845_3557636_-\|tRNA	aspartate--tRNA ligase	A0A1V0SAC0	Catovirus	6.5e-08	25.5
WP_003807035.1\|3557676_3558342_-	DUF502 domain-containing protein	A0A2I7S9X1	Vibrio_phage	6.7e-11	28.4
WP_010929971.1\|3558342_3558651_-	FmdB family transcriptional regulator	NA	NA	NA	NA
WP_010929970.1\|3558816_3560103_-	membrane protein	NA	NA	NA	NA
WP_077108686.1\|3561536_3562487_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_010929968.1\|3564438_3565653_-	formate-dependent phosphoribosylglycinamide formyltransferase	NA	NA	NA	NA
WP_003815171.1\|3565758_3566748_+	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	4.3e-38	37.7
WP_003815172.1\|3566744_3567353_+	HAD-IIIA family hydrolase	E3T535	Cafeteria_roenbergensis_virus	5.2e-10	26.1
WP_010929967.1\|3567365_3567995_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_003815175.1\|3567991_3568612_+	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_003815177.1\|3568643_3569435_+	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.5e-20	27.4
WP_003815179.1\|3570277_3570742_+	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_010929965.1\|3570760_3571687_+	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_010929964.1\|3571740_3573027_-	cytochrome c	NA	NA	NA	NA
WP_003815183.1\|3573957_3574830_+	RNase adapter RapZ	A0A1P8D5W0	Corynebacterium_phage	2.4e-08	34.5
WP_010929963.1\|3574826_3575777_+	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	6.9e-17	47.2
WP_005012067.1\|3575875_3576826_+\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA
WP_020699695.1\|3576930_3577161_-	hypothetical protein	NA	NA	NA	NA
WP_019247263.1\|3577287_3577677_-	SRPBCC family protein	NA	NA	NA	NA
WP_010929962.1\|3577693_3580075_-	xanthine dehydrogenase family protein molybdopterin-binding subunit	NA	NA	NA	NA
WP_023853194.1\|3580067_3581444_-	FAD binding domain in molybdopterin dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	2.4e-18	37.3
WP_010929960.1\|3581459_3582455_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003819054.1\|3582473_3583466_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_003807624.1\|3583706_3584267_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_010929959.1\|3584271_3584598_-	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_010929958.1\|3584634_3585447_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_003807618.1\|3585457_3586540_-	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	3.3e-07	40.7
WP_010929957.1\|3586626_3587901_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_010929956.1\|3588623_3589574_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_005012067.1\|3589672_3590623_-\|transposase	IS481-like element IS481 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018039

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection