CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP013845	Clostridium botulinum strain A634 chromosome, complete genome	2 crisprs	DEDDh,csa3,DinG,WYL,cas3	0	2	6	1
NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	3 crisprs	cas8b1,cas7b,cas5,cas3,DEDDh,c2c4_V-U1,cas14j	1	14	3	0
NZ_CP013846	Clostridium botulinum strain A634 plasmid pRSJ19_1, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP013845_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013845_1

2324566-2324730

Orphan

III-B

Consensus_repeat	Method
GAATTTAAATACATCCTATGTTATTGTTCAAC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP013845_1

>merge|NZ_CP013845|1|2324566-2324730|CRISPRCasFinder
ATGCTCAAATACATCTCATGTTATTGTTCAACTAGTAACGCTCTTTTTGCAGCAGAAATGAGTTTTAAATTTAAATACATCTTATGTTATTGTTCAACAAAGAATATAAATATTGAACATTATGAAATCTATGCATTTAAATACATCTCATGTTGTTGTTCAATC

>NZ_CP013845|1|1|2324566-2324730|CRISPRCasFinder
ATGCTCAAATACATCTCATGTTATTGTTCAAC	TAGTAACGCTCTTTTTGCAGCAGAAATGAGTTTT
AAATTTAAATACATCTTATGTTATTGTTCAAC	AAAGAATATAAATATTGAACATTATGAAATCTAT
GCATTTAAATACATCTCATGTTGTTGTTCAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013845.1\|WP_024931534.1\|2327531_2328329_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
NZ_CP013845.1\|WP_045904293.1\|2319527_2319791_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238518
NZ_CP013845.1\|WP_061323491.1\|2329431_2329848_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP013845.1\|WP_021135895.1\|2337905_2338289_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NZ_CP013845.1\|WP_164076805.1\|2319114_2319288_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013845.1\|WP_021135892.1\|2335063_2335630_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380313
NZ_CP013845.1\|WP_045904387.1\|2332593_2334087_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP013845.1\|WP_021135889.1\|2330305_2330974_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP013845.1\|WP_021135890.1\|2331348_2332269_-\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NZ_CP013845.1\|WP_003361920.1\|2316695_2317133_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP013845.1\|WP_061323489.1\|2325437_2327435_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239241
NZ_CP013845.1\|WP_024931528.1\|2319880_2320324_+\|M24-family-metallopeptidase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379789
NZ_CP013845.1\|WP_024931531.1\|2322631_2323522_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP013845.1\|WP_024931530.1\|2321884_2322625_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP013845.1\|WP_024931532.1\|2323822_2324344_+\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
NZ_CP013845.1\|WP_012721052.1\|2320374_2321781_+\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|340904
NZ_CP013845.1\|WP_061323554.1\|2328376_2328670_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013845.1\|WP_003361921.1\|2317156_2317873_-\|transaldolase	unknown	unknown	gnl\|CDD\|183481
NZ_CP013845.1\|WP_061323493.1\|2336408_2337872_+\|lipase	unknown	unknown	gnl\|CDD\|335313
NZ_CP013845.1\|WP_061323487.1\|2318262_2318931_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274303

Protein	Function_ID	Function_description	E-value
NZ_CP013845.1\|WP_024931534.1\|2327531_2328329_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.60332e-15
NZ_CP013845.1\|WP_045904293.1\|2319527_2319791_+\|hypothetical-protein	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	2.4431e-12
NZ_CP013845.1\|WP_061323491.1\|2329431_2329848_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	5.00027e-14
NZ_CP013845.1\|WP_021135895.1\|2337905_2338289_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.38068e-33
NZ_CP013845.1\|WP_061323493.1\|2336408_2337872_+\|lipase	gnl\|CDD\|335313	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II. Platelet-activating factor acetylhydrolase (PAF-AH) is a subfamily of phospholipases A2, responsible for inactivation of platelet-activating factor through cleavage of an acetyl group. Three known PAF-AHs are the brain heterotrimeric PAF-AH Ib, whose catalytic beta and gamma subunits are aligned in pfam02266, the extracellular, plasma PAF-AH (pPAF-AH), and the intracellular PAF-AH isoform II (PAF-AH II). This family aligns pPAF-AH and PAF-AH II, whose similarity was previously noted.	1.18287e-17
NZ_CP013845.1\|WP_021135892.1\|2335063_2335630_-\|nitroreductase	gnl\|CDD\|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	5.54517e-37
NZ_CP013845.1\|WP_045904387.1\|2332593_2334087_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	5.8598e-120
NZ_CP013845.1\|WP_021135889.1\|2330305_2330974_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.01281e-22
NZ_CP013845.1\|WP_021135890.1\|2331348_2332269_-\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.03068e-89
NZ_CP013845.1\|WP_003361920.1\|2316695_2317133_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	5.7325e-38
NZ_CP013845.1\|WP_061323489.1\|2325437_2327435_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
NZ_CP013845.1\|WP_024931528.1\|2319880_2320324_+\|M24-family-metallopeptidase-C-terminal-domain-containing-protein	gnl\|CDD\|379789	pfam16188, Peptidase_M24_C, C-terminal region of peptidase_M24. This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.	2.88107e-29
NZ_CP013845.1\|WP_024931531.1\|2322631_2323522_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.85308e-29
NZ_CP013845.1\|WP_024931530.1\|2321884_2322625_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.76105e-12
NZ_CP013845.1\|WP_024931532.1\|2323822_2324344_+\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	1.35086e-25
NZ_CP013845.1\|WP_012721052.1\|2320374_2321781_+\|peptide-MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.35095e-120
NZ_CP013845.1\|WP_003361921.1\|2317156_2317873_-\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.16561e-157
NZ_CP013845.1\|WP_061323487.1\|2318262_2318931_-\|hypothetical-protein	gnl\|CDD\|274303	TIGR02794, Protein_TolA, TolA protein. TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	4.45496e-07

>NZ_CP013845.1|WP_024931532.1|2323822_2324344_+|DUF4825-domain-containing-protein
MKNKFKILVPLVLILSLNLIGCGINSEKSSKENVKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANEYSAGFSLQTSKKPYEITVNYKANENLGEENYNKFWKDNKVEKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKSLEQKYGNLKNLFKDNDSLNKFLNN
>NZ_CP013845.1|WP_024931531.1|2322631_2323522_-|AraC-family-transcriptional-regulator
MNYRKDIENCIDYIEEHIKEPLTLKEITQEIGYSSYHFCRVFSFLKGMPLMEYVRKRRLSLSTIDLLEGKKIIDVAFKWGFETPSSFARAFRKEFGCSPSQYIKKMKFYYKSENNLILSKFMNDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYNGENLESKLYKILSPLKHGEVGLCIPCSDSGDITYLLGVIVEDFSKVTSDMITVEVPKAQYAVFTTNPVNTVDSKDQREFAKIIKESWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>NZ_CP013845.1|WP_024931530.1|2321884_2322625_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPGDELQFYLQYAKKEMKILEPLCGSGRFLIPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEEFSPKEKYDYIFITSGSFSLFLDEDIAFNVMVKMKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDNLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NZ_CP013845.1|WP_012721052.1|2320374_2321781_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEVGKYPVSKDKKNSTESVSTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NZ_CP013845.1|WP_024931528.1|2319880_2320324_+|M24-family-metallopeptidase-C-terminal-domain-containing-protein
MDILARASFWNRNLNFSHDTGHGVRYLMSIHEAPTGFRWQYRANETHPFEEEMVITDESDIYIAGSHGVRIENELLVCKEEKNEYGQFMYFEPISYVPIDLDAINPDLMTEEEKTWLNEYHKSAYEKISPYLNDKEKQWLKEYTREI
>NZ_CP013845.1|WP_045904293.1|2319527_2319791_+|hypothetical-protein
MNEVHLFINENKLSHEIKSSLKKNGALFIHPYNKIYKEVITEISASNKLDEFRAEQGGFICPSFEPISSFGEHVAIVYTTLQPLKQM
>NZ_CP013845.1|WP_164076805.1|2319114_2319288_-|hypothetical-protein
MKNKVANNLNFVAAILLGIVAMLNFFQHKTLLGITYICSAICFCTLEFSKKKNANHK
>NZ_CP013845.1|WP_061323487.1|2318262_2318931_-|hypothetical-protein
MDKFRNMKKSHIALLVVMYMVLMGSFPRFTGWATIFSAIAVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMGEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEENKIKVENEQAQAAFAQSTGKGNSNDQSNESENVDNNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEGLSPCSVCNP
>NZ_CP013845.1|WP_003361921.1|2317156_2317873_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVKIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NZ_CP013845.1|WP_003361920.1|2316695_2317133_-|PTS-sugar-transporter-subunit-IIA
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPETGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NZ_CP013845.1|WP_061323489.1|2325437_2327435_-|FAD-dependent-oxidoreductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNKRGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGSKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKILVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKKVVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMAAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKEFGADEVLLATGSSPRTLTIEGADKVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLVDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYNQVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>NZ_CP013845.1|WP_024931534.1|2327531_2328329_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEKRETMYQLEALKRAQYYMNLADAIEEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQKIIHQWVKAMPTVQLGVFDSRMGMSNFGYLVKTKKREELELPLGLHAKEIKSTSCIHTIVMADEDFTQQPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NZ_CP013845.1|WP_061323554.1|2328376_2328670_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPILNLLLLIKGIVNYFNRAAG
>NZ_CP013845.1|WP_061323491.1|2329431_2329848_+|carboxymuconolactone-decarboxylase-family-protein
MAKITFSQEGLTPFQQLLGHNKYIMEKWTSLEECFFNSNTFTHELKEEVRRTLAFNNGCQYCMSKGKPSNEITDSKILIATKIADIISKNQLIDNEYFNRLKNEFTDNEVSELLALICFITASQKFGALLDLQPSCSI
>NZ_CP013845.1|WP_021135889.1|2330305_2330974_-|class-I-SAM-dependent-methyltransferase
MEDYNIVKNDFNEISQLDELTWNHNNCYFEHLIKLIPNNVETCLEIGCGKGELSFMLSKKSQKVIAVDLADKMIESAKVLHPNNNIGYICENILDMKFEDNSFDVIITTATAHHLPYDWLLCFAKNKLKKGGKLIILDLVKAKSLSDYIIWGSAIIPNIVMNLIKNGRLQKDDAHSKEVWERHGKHDRYMTINEIKSLAQKHIPTAKVRRKLFWRYLLVWQK
>NZ_CP013845.1|WP_021135890.1|2331348_2332269_-|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNLSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGMNKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVARGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NZ_CP013845.1|WP_045904387.1|2332593_2334087_+|PLP-dependent-aminotransferase-family-protein
MNIKIDKNSLITITQQLVHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERNSAVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRLKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIARYNDILIVEDDPWNEISYKREKIKTIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NZ_CP013845.1|WP_021135892.1|2335063_2335630_-|nitroreductase
METINAIKERRSIRKFQDKMIAKETIQELLELSIKAPSGKNRQPWRFVVLQGKKKDELVNLMTNVAKILKEKGTNIGSFEISINSINEAPVVILVFNGFSNFEEDYNHYRLLTDTQSIGASIQTMILAAQDLGLGSLWICDIFYSQKEICSWLNRKDELVAAVAIGYVNQSPYPRPRKPWREVTEWMS
>NZ_CP013845.1|WP_061323493.1|2336408_2337872_+|lipase
MRMLEVILFLVILTTTGGILFVKPNRRLDIVFLLSVVLVMLLHGTINHFRIQMLPSYAVALVLIIVLIHRLINSNSKHKSQSIPKSLLKKSFVSILVLIFIGTSAYLSFLLPVFTMPKPTGNYGIGTVSAHLTDESRAETLSTSPDDKREIMVNVWYPVDQKDIKGKTVEHYPSELGEAISLVFNIPKQLFTHLSQVPTHVVQGAKISTAEPKYPVLLFSPGVRSTRFQSLTTIEELVSHGYIVVGLDHPYTSAKVTFPDGRSIFYKPDTKSMTASELYKHNIGNVGIRVADVRFLLDTLTKWNKKDPNALLQGKLDLERIGMFGHSYGGATTAEALAQDNRLKAGVSLEGGFWGSVSQKGLKQPFMYLMSGGTAASFDPSTIKKDKVFYEEFIPDLQSVMNKSTNNTYYLTVDHFIHQSFTDISIISPLLFAKDIDPVHNIDITRSYVRTFFDQYLKGNHSILLDGPSSKYPEVKFSDIYTKKRLN
>NZ_CP013845.1|WP_021135895.1|2337905_2338289_+|MerR-family-transcriptional-regulator
MDKMTRGELAKQTGISTSTIRYYEDSGILPAPKRIANGYRIYTDDYLVKIKFIKDAKSLGYSLKEIKEILQILSQEMDGENLKGLVKNKICEIEDRIKTLHSIQRMLTDLLNTSEEDIQNYLQSFRI

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Crispr_ID: NZ_CP013845_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013845_2

2324982-2325145

Orphan

III-B

Consensus_repeat	Method
GAATTTAAATACATCCTATGTTATTGTTCAAC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP013845_2

>merge|NZ_CP013845|2|2324982-2325145|CRISPRCasFinder
CTGCTTAAATACATCTCATGTTAATGTTCAACAGGTGGAGTATTAGAAGATATGCATCTATATAAAGAATTTAAATACATCCTATGTTATTGTTCAACTACAATATATAATGATAAAATAAATCAATTGAATGAATTTAAATACATCCTATGTTATTGTTCAAC

>NZ_CP013845|2|2|2324982-2325145|CRISPRCasFinder
CTGCTTAAATACATCTCATGTTAATGTTCAAC	AGGTGGAGTATTAGAAGATATGCATCTATATAAA
GAATTTAAATACATCCTATGTTATTGTTCAAC	TACAATATATAATGATAAAATAAATCAATTGAAT
GAATTTAAATACATCCTATGTTATTGTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013845.1\|WP_024931534.1\|2327531_2328329_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
NZ_CP013845.1\|WP_045904293.1\|2319527_2319791_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238518
NZ_CP013845.1\|WP_061323491.1\|2329431_2329848_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP013845.1\|WP_021135895.1\|2337905_2338289_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NZ_CP013845.1\|WP_164076805.1\|2319114_2319288_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013845.1\|WP_021135892.1\|2335063_2335630_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380313
NZ_CP013845.1\|WP_045904387.1\|2332593_2334087_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP013845.1\|WP_021135889.1\|2330305_2330974_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP013845.1\|WP_021135890.1\|2331348_2332269_-\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NZ_CP013845.1\|WP_003361920.1\|2316695_2317133_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP013845.1\|WP_061323489.1\|2325437_2327435_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239241
NZ_CP013845.1\|WP_024931528.1\|2319880_2320324_+\|M24-family-metallopeptidase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379789
NZ_CP013845.1\|WP_024931531.1\|2322631_2323522_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP013845.1\|WP_024931530.1\|2321884_2322625_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP013845.1\|WP_024931532.1\|2323822_2324344_+\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
NZ_CP013845.1\|WP_012721052.1\|2320374_2321781_+\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|340904
NZ_CP013845.1\|WP_061323554.1\|2328376_2328670_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013845.1\|WP_003361921.1\|2317156_2317873_-\|transaldolase	unknown	unknown	gnl\|CDD\|183481
NZ_CP013845.1\|WP_061323493.1\|2336408_2337872_+\|lipase	unknown	unknown	gnl\|CDD\|335313
NZ_CP013845.1\|WP_061323487.1\|2318262_2318931_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274303

Protein	Function_ID	Function_description	E-value
NZ_CP013845.1\|WP_024931534.1\|2327531_2328329_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.60332e-15
NZ_CP013845.1\|WP_045904293.1\|2319527_2319791_+\|hypothetical-protein	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	2.4431e-12
NZ_CP013845.1\|WP_061323491.1\|2329431_2329848_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	5.00027e-14
NZ_CP013845.1\|WP_021135895.1\|2337905_2338289_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.38068e-33
NZ_CP013845.1\|WP_061323493.1\|2336408_2337872_+\|lipase	gnl\|CDD\|335313	pfam03403, PAF-AH_p_II, Platelet-activating factor acetylhydrolase, isoform II. Platelet-activating factor acetylhydrolase (PAF-AH) is a subfamily of phospholipases A2, responsible for inactivation of platelet-activating factor through cleavage of an acetyl group. Three known PAF-AHs are the brain heterotrimeric PAF-AH Ib, whose catalytic beta and gamma subunits are aligned in pfam02266, the extracellular, plasma PAF-AH (pPAF-AH), and the intracellular PAF-AH isoform II (PAF-AH II). This family aligns pPAF-AH and PAF-AH II, whose similarity was previously noted.	1.18287e-17
NZ_CP013845.1\|WP_021135892.1\|2335063_2335630_-\|nitroreductase	gnl\|CDD\|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	5.54517e-37
NZ_CP013845.1\|WP_045904387.1\|2332593_2334087_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	5.8598e-120
NZ_CP013845.1\|WP_021135889.1\|2330305_2330974_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.01281e-22
NZ_CP013845.1\|WP_021135890.1\|2331348_2332269_-\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.03068e-89
NZ_CP013845.1\|WP_003361920.1\|2316695_2317133_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	5.7325e-38
NZ_CP013845.1\|WP_061323489.1\|2325437_2327435_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
NZ_CP013845.1\|WP_024931528.1\|2319880_2320324_+\|M24-family-metallopeptidase-C-terminal-domain-containing-protein	gnl\|CDD\|379789	pfam16188, Peptidase_M24_C, C-terminal region of peptidase_M24. This is a short region at the C-terminus of a number of metallo-peptidases of the M24 family.	2.88107e-29
NZ_CP013845.1\|WP_024931531.1\|2322631_2323522_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.85308e-29
NZ_CP013845.1\|WP_024931530.1\|2321884_2322625_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.76105e-12
NZ_CP013845.1\|WP_024931532.1\|2323822_2324344_+\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	1.35086e-25
NZ_CP013845.1\|WP_012721052.1\|2320374_2321781_+\|peptide-MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.35095e-120
NZ_CP013845.1\|WP_003361921.1\|2317156_2317873_-\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.16561e-157
NZ_CP013845.1\|WP_061323487.1\|2318262_2318931_-\|hypothetical-protein	gnl\|CDD\|274303	TIGR02794, Protein_TolA, TolA protein. TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	4.45496e-07

>NZ_CP013845.1|WP_024931532.1|2323822_2324344_+|DUF4825-domain-containing-protein
MKNKFKILVPLVLILSLNLIGCGINSEKSSKENVKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANEYSAGFSLQTSKKPYEITVNYKANENLGEENYNKFWKDNKVEKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKSLEQKYGNLKNLFKDNDSLNKFLNN
>NZ_CP013845.1|WP_024931531.1|2322631_2323522_-|AraC-family-transcriptional-regulator
MNYRKDIENCIDYIEEHIKEPLTLKEITQEIGYSSYHFCRVFSFLKGMPLMEYVRKRRLSLSTIDLLEGKKIIDVAFKWGFETPSSFARAFRKEFGCSPSQYIKKMKFYYKSENNLILSKFMNDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYNGENLESKLYKILSPLKHGEVGLCIPCSDSGDITYLLGVIVEDFSKVTSDMITVEVPKAQYAVFTTNPVNTVDSKDQREFAKIIKESWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>NZ_CP013845.1|WP_024931530.1|2321884_2322625_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPGDELQFYLQYAKKEMKILEPLCGSGRFLIPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEEFSPKEKYDYIFITSGSFSLFLDEDIAFNVMVKMKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDNLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NZ_CP013845.1|WP_012721052.1|2320374_2321781_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEVGKYPVSKDKKNSTESVSTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NZ_CP013845.1|WP_024931528.1|2319880_2320324_+|M24-family-metallopeptidase-C-terminal-domain-containing-protein
MDILARASFWNRNLNFSHDTGHGVRYLMSIHEAPTGFRWQYRANETHPFEEEMVITDESDIYIAGSHGVRIENELLVCKEEKNEYGQFMYFEPISYVPIDLDAINPDLMTEEEKTWLNEYHKSAYEKISPYLNDKEKQWLKEYTREI
>NZ_CP013845.1|WP_045904293.1|2319527_2319791_+|hypothetical-protein
MNEVHLFINENKLSHEIKSSLKKNGALFIHPYNKIYKEVITEISASNKLDEFRAEQGGFICPSFEPISSFGEHVAIVYTTLQPLKQM
>NZ_CP013845.1|WP_164076805.1|2319114_2319288_-|hypothetical-protein
MKNKVANNLNFVAAILLGIVAMLNFFQHKTLLGITYICSAICFCTLEFSKKKNANHK
>NZ_CP013845.1|WP_061323487.1|2318262_2318931_-|hypothetical-protein
MDKFRNMKKSHIALLVVMYMVLMGSFPRFTGWATIFSAIAVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMGEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEENKIKVENEQAQAAFAQSTGKGNSNDQSNESENVDNNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEGLSPCSVCNP
>NZ_CP013845.1|WP_003361921.1|2317156_2317873_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVKIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NZ_CP013845.1|WP_003361920.1|2316695_2317133_-|PTS-sugar-transporter-subunit-IIA
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPETGAKNIRIGLLKLKNPVNFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NZ_CP013845.1|WP_061323489.1|2325437_2327435_-|FAD-dependent-oxidoreductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNKRGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGSKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGGSLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKILVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKKVVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMAAARVAAIRGHKVTLIEKNGYLGGNIVPGGVPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKEFGADEVLLATGSSPRTLTIEGADKVYSAEDVLMERKNVGEKVIIIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLVDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYNQVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>NZ_CP013845.1|WP_024931534.1|2327531_2328329_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEKRETMYQLEALKRAQYYMNLADAIEEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQKIIHQWVKAMPTVQLGVFDSRMGMSNFGYLVKTKKREELELPLGLHAKEIKSTSCIHTIVMADEDFTQQPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NZ_CP013845.1|WP_061323554.1|2328376_2328670_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPILNLLLLIKGIVNYFNRAAG
>NZ_CP013845.1|WP_061323491.1|2329431_2329848_+|carboxymuconolactone-decarboxylase-family-protein
MAKITFSQEGLTPFQQLLGHNKYIMEKWTSLEECFFNSNTFTHELKEEVRRTLAFNNGCQYCMSKGKPSNEITDSKILIATKIADIISKNQLIDNEYFNRLKNEFTDNEVSELLALICFITASQKFGALLDLQPSCSI
>NZ_CP013845.1|WP_021135889.1|2330305_2330974_-|class-I-SAM-dependent-methyltransferase
MEDYNIVKNDFNEISQLDELTWNHNNCYFEHLIKLIPNNVETCLEIGCGKGELSFMLSKKSQKVIAVDLADKMIESAKVLHPNNNIGYICENILDMKFEDNSFDVIITTATAHHLPYDWLLCFAKNKLKKGGKLIILDLVKAKSLSDYIIWGSAIIPNIVMNLIKNGRLQKDDAHSKEVWERHGKHDRYMTINEIKSLAQKHIPTAKVRRKLFWRYLLVWQK
>NZ_CP013845.1|WP_021135890.1|2331348_2332269_-|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNLSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGMNKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIADIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVARGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NZ_CP013845.1|WP_045904387.1|2332593_2334087_+|PLP-dependent-aminotransferase-family-protein
MNIKIDKNSLITITQQLVHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERNSAVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRLKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIARYNDILIVEDDPWNEISYKREKIKTIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NZ_CP013845.1|WP_021135892.1|2335063_2335630_-|nitroreductase
METINAIKERRSIRKFQDKMIAKETIQELLELSIKAPSGKNRQPWRFVVLQGKKKDELVNLMTNVAKILKEKGTNIGSFEISINSINEAPVVILVFNGFSNFEEDYNHYRLLTDTQSIGASIQTMILAAQDLGLGSLWICDIFYSQKEICSWLNRKDELVAAVAIGYVNQSPYPRPRKPWREVTEWMS
>NZ_CP013845.1|WP_061323493.1|2336408_2337872_+|lipase
MRMLEVILFLVILTTTGGILFVKPNRRLDIVFLLSVVLVMLLHGTINHFRIQMLPSYAVALVLIIVLIHRLINSNSKHKSQSIPKSLLKKSFVSILVLIFIGTSAYLSFLLPVFTMPKPTGNYGIGTVSAHLTDESRAETLSTSPDDKREIMVNVWYPVDQKDIKGKTVEHYPSELGEAISLVFNIPKQLFTHLSQVPTHVVQGAKISTAEPKYPVLLFSPGVRSTRFQSLTTIEELVSHGYIVVGLDHPYTSAKVTFPDGRSIFYKPDTKSMTASELYKHNIGNVGIRVADVRFLLDTLTKWNKKDPNALLQGKLDLERIGMFGHSYGGATTAEALAQDNRLKAGVSLEGGFWGSVSQKGLKQPFMYLMSGGTAASFDPSTIKKDKVFYEEFIPDLQSVMNKSTNNTYYLTVDHFIHQSFTDISIISPLLFAKDIDPVHNIDITRSYVRTFFDQYLKGNHSILLDGPSSKYPEVKFSDIYTKKRLN
>NZ_CP013845.1|WP_021135895.1|2337905_2338289_+|MerR-family-transcriptional-regulator
MDKMTRGELAKQTGISTSTIRYYEDSGILPAPKRIANGYRIYTDDYLVKIKFIKDAKSLGYSLKEIKEILQILSQEMDGENLKGLVKNKICEIEDRIKTLHSIQRMLTDLLNTSEEDIQNYLQSFRI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	1269-1302	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	56713-56746	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	177272-177305	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	192981-193014	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	33299-33332	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	107476-107509	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	248506-248539	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	229227-229260	1	0.971
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	134176-134209	2	0.941
NZ_CP013845_2	2.2\|2325080\|34\|NZ_CP013845\|CRISPRCasFinder	2325080-2325113	34	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	247974-248007	2	0.941
NZ_CP013845_1	1.2\|2324664\|34\|NZ_CP013845\|CRISPRCasFinder	2324664-2324697	34	MT774405	CrAssphage cr115_1, complete genome	77868-77901	8	0.765
NZ_CP013845_1	1.2\|2324664\|34\|NZ_CP013845\|CRISPRCasFinder	2324664-2324697	34	JX415535	Escherichia phage ECBP1, complete genome	3653-3686	8	0.765
NZ_CP013845_1	1.2\|2324664\|34\|NZ_CP013845\|CRISPRCasFinder	2324664-2324697	34	MH669274	Escherichia phage PD38, complete genome	2767-2800	8	0.765
NZ_CP013845_1	1.2\|2324664\|34\|NZ_CP013845\|CRISPRCasFinder	2324664-2324697	34	KJ135004	Enterobacteria phage Bp4, complete genome	69783-69816	8	0.765
NZ_CP013845_1	1.2\|2324664\|34\|NZ_CP013845\|CRISPRCasFinder	2324664-2324697	34	NC_010180	Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence	132080-132113	9	0.735
NZ_CP013845_1	1.2\|2324664\|34\|NZ_CP013845\|CRISPRCasFinder	2324664-2324697	34	MN694536	Marine virus AFVG_250M991, complete genome	5402-5435	9	0.735
NZ_CP013845_1	1.2\|2324664\|34\|NZ_CP013845\|CRISPRCasFinder	2324664-2324697	34	NZ_CP035189	Bacillus licheniformis strain SRCM103914 plasmid unnamed1, complete sequence	141895-141928	10	0.706

1. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatataatgataagataaatcaattgaat	Protospacer
******************.***************

2. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatacaatgataaaataaatcaattgaat	Protospacer
*********.************************

3. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatacaatgataaaataaatcaattgaat	Protospacer
*********.************************

4. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatataatgataagataaatcaattgaat	Protospacer
******************.***************

5. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatataatgataagataaatcaattgaat	Protospacer
******************.***************

6. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatacaatgataaaataaatcaattgaat	Protospacer
*********.************************

7. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatataatgataagataaatcaattgaat	Protospacer
******************.***************

8. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 1, identity: 0.971

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatacaatgataaaataaatcaattgaat	Protospacer
*********.************************

9. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 2, identity: 0.941

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatataatgacaagataaatcaattgaat	Protospacer
***************.**.***************

10. spacer 2.2|2325080|34|NZ_CP013845|CRISPRCasFinder matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 2, identity: 0.941

tacaatatataatgataaaataaatcaattgaat	CRISPR spacer
tacaatatataatgacaagataaatcaattgaat	Protospacer
***************.**.***************

11. spacer 1.2|2324664|34|NZ_CP013845|CRISPRCasFinder matches to MT774405 (CrAssphage cr115_1, complete genome) position: , mismatch: 8, identity: 0.765

aaagaatataaatattgaacattatgaaatctat	CRISPR spacer
gcatcatataaatattgaatattatcaaatacat	Protospacer
. *  **************.***** **** .**

12. spacer 1.2|2324664|34|NZ_CP013845|CRISPRCasFinder matches to JX415535 (Escherichia phage ECBP1, complete genome) position: , mismatch: 8, identity: 0.765

aaagaatataaatattgaacattatgaaatctat	CRISPR spacer
aagtagcatgaatattgaaaattatgaaatcact	Protospacer
**. *..**.********* ***********  *

13. spacer 1.2|2324664|34|NZ_CP013845|CRISPRCasFinder matches to MH669274 (Escherichia phage PD38, complete genome) position: , mismatch: 8, identity: 0.765

aaagaatataaatattgaacattatgaaatctat	CRISPR spacer
aagtagcatgaatattgaaaattatgaaatcact	Protospacer
**. *..**.********* ***********  *

14. spacer 1.2|2324664|34|NZ_CP013845|CRISPRCasFinder matches to KJ135004 (Enterobacteria phage Bp4, complete genome) position: , mismatch: 8, identity: 0.765

aaagaatataaatattgaacattatgaaatctat	CRISPR spacer
aagtagcatgaatattgaaaattatgaaatcact	Protospacer
**. *..**.********* ***********  *

15. spacer 1.2|2324664|34|NZ_CP013845|CRISPRCasFinder matches to NC_010180 (Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence) position: , mismatch: 9, identity: 0.735

aaagaatataaatattgaacattatgaaatctat	CRISPR spacer
taggaatataaatatagaccattatgaaagaatc	Protospacer
 *.************ ** **********    .

16. spacer 1.2|2324664|34|NZ_CP013845|CRISPRCasFinder matches to MN694536 (Marine virus AFVG_250M991, complete genome) position: , mismatch: 9, identity: 0.735

aaagaatataaatattgaacattatgaaatctat	CRISPR spacer
taaagatttaaatattaaacattatgaaaccata	Protospacer
 **..** ********.************.*

17. spacer 1.2|2324664|34|NZ_CP013845|CRISPRCasFinder matches to NZ_CP035189 (Bacillus licheniformis strain SRCM103914 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

aaagaatataaatattgaacattatgaaatctat	CRISPR spacer
acaagatataaataatgaacagtatgaaagaata	Protospacer
* *..********* ****** *******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

573634 : 580890

Clostridium_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061323679.1\|573634_574456_+	C40 family peptidase	A0A0A8WF62	Clostridium_phage	1.0e-21	46.1
WP_061323683.1\|575312_575660_+	hypothetical protein	A0A0A7RTL9	Clostridium_phage	1.7e-29	60.5
WP_061323685.1\|575678_575828_-	hypothetical protein	NA	NA	NA	NA
WP_061323687.1\|575928_576198_+	hypothetical protein	A0A0A7RTH0	Clostridium_phage	1.3e-13	47.2
WP_061323689.1\|576345_577155_+	DUF2935 domain-containing protein	A0A2I2L551	Orpheovirus	6.7e-45	41.0
WP_012720988.1\|578059_579436_+	PhoH family protein	A0A141HS37	Bacillus_phage	2.3e-106	44.3
WP_061323691.1\|579885_580890_+	phosphodiester glycosidase family protein	A0A1P8CWN9	Bacillus_phage	5.6e-09	30.7

DBSCAN-SWA_2

1420884 : 1433147

Bacillus_phage(60.0%)

transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003359768.1\|1420884_1421190_+\|transposase	transposase	NA	NA	NA	NA
WP_003359767.1\|1421189_1422065_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.9e-39	38.2
WP_061324403.1\|1422373_1424746_+	cation-translocating P-type ATPase	M1HM40	Paramecium_bursaria_Chlorella_virus	2.8e-35	24.8
WP_003359767.1\|1424876_1425752_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.9e-39	38.2
WP_003359768.1\|1425751_1426057_-\|transposase	transposase	NA	NA	NA	NA
WP_004442306.1\|1426473_1428192_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.4e-63	32.9
WP_004442305.1\|1428483_1429278_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_004442303.1\|1429441_1429798_+	diguanylate cyclase	NA	NA	NA	NA
WP_012720543.1\|1430228_1431122_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	8.2e-12	29.9
WP_004442299.1\|1431158_1431623_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_003402696.1\|1431935_1432151_+	hypothetical protein	NA	NA	NA	NA
WP_004442155.1\|1432188_1432617_+	HIT family protein	NA	NA	NA	NA
WP_004442152.1\|1432772_1433147_-\|holin	phage holin family protein	NA	NA	NA	NA

DBSCAN-SWA_3

1993693 : 2059443

uncultured_Caudovirales_phage(40.54%)

integrase,plate,tRNA,capsid,portal,transposase,tail

attL 2036855:2036871|attR 2049595:2049611

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061323058.1\|1993693_1995667_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012720776.1\|1995666_1996797_-\|integrase	tyrosine-type recombinase/integrase	H7BW99	unidentified_phage	5.5e-05	25.3
WP_003363123.1\|1996949_1997954_-	type II secretion system F family protein	NA	NA	NA	NA
WP_061323065.1\|1999080_1999323_-	hypothetical protein	NA	NA	NA	NA
WP_061323066.1\|1999507_2000278_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	9.3e-89	64.8
WP_003356211.1\|2000321_2000516_-	hypothetical protein	NA	NA	NA	NA
WP_012100300.1\|2000529_2000784_-	hemolysin XhlA family protein	NA	NA	NA	NA
WP_061323069.1\|2000854_2001001_-	XkdX family protein	A0A0A7RTH5	Clostridium_phage	1.8e-09	64.4
WP_061323072.1\|2001000_2001201_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_061323074.1\|2001211_2003917_-	exo-alpha-sialidase	I1TJW8	Clostridium_phage	4.3e-80	36.7
WP_061323077.1\|2003916_2005281_-\|plate	BppU family phage baseplate upper protein	A0A0A7S181	Clostridium_phage	4.5e-86	78.5
WP_061323080.1\|2005296_2006964_-\|tail	phage tail protein	A0A0A7RUI9	Clostridium_phage	1.6e-77	42.3
WP_061323083.1\|2006963_2007641_-\|tail	phage tail protein	A0A0A7RWN1	Clostridium_phage	5.8e-42	41.1
WP_061323086.1\|2007640_2010238_-\|tail	phage tail tape measure protein	A0A0A7RU22	Clostridium_phage	3.4e-82	62.6
WP_101514344.1\|2010290_2010467_-	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_061323088.1\|2010490_2011030_-	hypothetical protein	NA	NA	NA	NA
WP_061323091.1\|2011090_2011684_-	hypothetical protein	A0A1J1J8Y5	Escherichia_phage	2.3e-63	60.4
WP_061323094.1\|2011683_2012028_-	hypothetical protein	NA	NA	NA	NA
WP_061323096.1\|2012027_2012537_-	hypothetical protein	NA	NA	NA	NA
WP_061323099.1\|2012537_2012969_-	hypothetical protein	A0A0A8WJ92	Clostridium_phage	1.3e-39	56.6
WP_061323102.1\|2012965_2013310_-\|capsid	capsid protein	F6K8R4	Clostridium_phage	1.0e-15	42.5
WP_061323104.1\|2013309_2013720_-	hypothetical protein	NA	NA	NA	NA
WP_061323107.1\|2013721_2013985_-	hypothetical protein	NA	NA	NA	NA
WP_061323109.1\|2013985_2014168_-	hypothetical protein	NA	NA	NA	NA
WP_061323112.1\|2014213_2015104_-\|capsid	phage major capsid protein	A0A0H3U2U7	Staphylococcus_phage	1.4e-56	42.4
WP_061323115.1\|2015121_2015715_-	DUF4355 domain-containing protein	A0A2H4J4P4	uncultured_Caudovirales_phage	3.0e-18	29.0
WP_061293671.1\|2015811_2016468_-	hypothetical protein	NA	NA	NA	NA
WP_061323118.1\|2016617_2017346_-\|capsid	minor capsid protein	NA	NA	NA	NA
WP_021106712.1\|2017335_2018610_-\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	8.7e-116	52.6
WP_021106711.1\|2018613_2020347_-	hypothetical protein	A0A1V0DZW7	Clostridioides_phage	5.1e-252	72.4
WP_021106710.1\|2020363_2021068_-	DUF4145 domain-containing protein	A0A1L2JZ52	Aeribacillus_phage	4.9e-44	41.8
WP_061323120.1\|2021136_2021328_-	hypothetical protein	NA	NA	NA	NA
WP_061323123.1\|2021591_2022008_-	helix-turn-helix domain-containing protein	A0A2H4J863	uncultured_Caudovirales_phage	2.4e-43	68.9
WP_061323126.1\|2022127_2022559_-	RNA polymerase subunit sigma	A0A2H4J015	uncultured_Caudovirales_phage	4.5e-48	72.7
WP_061323128.1\|2022937_2024803_-	DNA primase	A0A2H4J1M0	uncultured_Caudovirales_phage	0.0e+00	87.4
WP_158644387.1\|2025008_2025161_+	hypothetical protein	NA	NA	NA	NA
WP_061323131.1\|2025355_2025685_-	nucleoside triphosphate pyrophosphohydrolase family protein	A0A2H4J7H8	uncultured_Caudovirales_phage	8.7e-44	79.4
WP_061323197.1\|2025681_2025948_-	DUF1599 domain-containing protein	A0A2H4J4N1	uncultured_Caudovirales_phage	1.0e-31	81.6
WP_158644388.1\|2026217_2026355_-	hypothetical protein	NA	NA	NA	NA
WP_170015855.1\|2026365_2026515_-	hypothetical protein	NA	NA	NA	NA
WP_061323133.1\|2026707_2027265_-	DUF4145 domain-containing protein	C7BGG4	Burkholderia_phage	8.7e-12	31.4
WP_061323136.1\|2027448_2029143_-	hypothetical protein	A0A2H4J041	uncultured_Caudovirales_phage	1.7e-292	84.6
WP_154695698.1\|2029142_2029307_-	hypothetical protein	NA	NA	NA	NA
WP_061323139.1\|2029359_2029818_-	DUF669 domain-containing protein	A0A2H4J1S8	uncultured_Caudovirales_phage	5.1e-58	68.2
WP_061323142.1\|2029820_2030102_-	hypothetical protein	NA	NA	NA	NA
WP_061323144.1\|2030101_2031892_-	AAA family ATPase	A0A2H4J7Q2	uncultured_Caudovirales_phage	2.7e-232	80.0
WP_014521350.1\|2031896_2032064_-	hypothetical protein	NA	NA	NA	NA
WP_061323147.1\|2032069_2032873_-	hypothetical protein	A0A2H4J786	uncultured_Caudovirales_phage	1.4e-132	84.3
WP_061323150.1\|2032865_2033195_-	hypothetical protein	NA	NA	NA	NA
WP_061323152.1\|2033199_2033496_-	VRR-NUC domain-containing protein	A0A2H4J095	uncultured_Caudovirales_phage	5.1e-43	85.6
WP_061323154.1\|2033495_2034311_-	DUF1351 domain-containing protein	A0A2H4J082	uncultured_Caudovirales_phage	5.6e-116	78.9
WP_061323200.1\|2034311_2035604_-	helicase SNF2	A0A2H4J064	uncultured_Caudovirales_phage	3.1e-193	77.0
WP_003355976.1\|2035618_2035789_-	hypothetical protein	NA	NA	NA	NA
WP_061323157.1\|2035802_2036096_-	hypothetical protein	NA	NA	NA	NA
WP_061323166.1\|2036834_2037164_-	hypothetical protein	NA	NA	NA	NA
2036855:2036871	attL	NA	NA	NA	NA
WP_061323169.1\|2037164_2037368_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_061323174.1\|2037575_2038088_+	helix-turn-helix domain-containing protein	A0A0A7RTK4	Clostridium_phage	4.7e-12	29.5
WP_061323176.1\|2038137_2038554_+	ImmA/IrrE family metallo-endopeptidase	I3VYZ2	Thermoanaerobacterium_phage	1.8e-06	30.1
WP_061323179.1\|2039112_2040183_+\|integrase	site-specific integrase	B3GVW7	Streptococcus_phage	4.2e-31	32.1
WP_024932288.1\|2041648_2042722_-	hypothetical protein	NA	NA	NA	NA
WP_021136124.1\|2042722_2043544_-	diaminopimelate epimerase	NA	NA	NA	NA
WP_024932287.1\|2043797_2045528_+	fibronectin/fibrinogen-binding protein	NA	NA	NA	NA
WP_003362855.1\|2045596_2046337_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_003362858.1\|2046888_2047266_-	HIT family protein	D7NW73	Streptomyces_phage	7.4e-15	46.2
WP_061323183.1\|2047778_2049182_+	glutamate decarboxylase	NA	NA	NA	NA
WP_003362860.1\|2049493_2049835_-	hypothetical protein	NA	NA	NA	NA
2049595:2049611	attR	NA	NA	NA	NA
WP_024932335.1\|2050339_2052049_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.3e-10	32.0
WP_021136603.1\|2052518_2054093_-	clostripain	NA	NA	NA	NA
WP_003362863.1\|2054572_2055226_+	hypothetical protein	NA	NA	NA	NA
WP_061323185.1\|2055231_2055933_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.6e-34	34.4
WP_039774291.1\|2055922_2057833_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.0e-19	24.4
WP_003359768.1\|2058262_2058568_+\|transposase	transposase	NA	NA	NA	NA
WP_003359767.1\|2058567_2059443_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.9e-39	38.2

DBSCAN-SWA_4

2649762 : 2742528

Clostridium_phage(50.0%)

integrase,bacteriocin,tRNA,protease,terminase,capsid,portal,head,tail

attL 2674854:2674872|attR 2750375:2750393

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004441622.1\|2649762_2652402_-\|tRNA	alanine--tRNA ligase	A0A2K9L3D8	Tupanvirus	1.8e-62	32.8
WP_004441624.1\|2652897_2653926_-	AI-2E family transporter	NA	NA	NA	NA
WP_004441628.1\|2653938_2654427_-	PRC-barrel domain-containing protein	NA	NA	NA	NA
WP_004441630.1\|2654607_2655036_-	Fe-S cluster assembly scaffold protein NifU	A0A2H4N7M4	Lake_Baikal_phage	4.2e-30	54.5
WP_004441634.1\|2655037_2656231_-	cysteine desulfurase NifS	H7BUW1	unidentified_phage	1.1e-43	42.1
WP_004441637.1\|2656223_2656670_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_004441638.1\|2656890_2658141_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	3.7e-87	42.5
WP_061323305.1\|2658308_2659076_-	histidinol phosphate phosphatase	NA	NA	NA	NA
WP_012721171.1\|2659210_2660119_-	AEC family transporter	NA	NA	NA	NA
WP_004441647.1\|2660226_2661093_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	7.4e-10	32.6
WP_004441658.1\|2661420_2662005_+	sulfurtransferase-like selenium metabolism protein YedF	NA	NA	NA	NA
WP_004440593.1\|2662191_2663181_-	ornithine cyclodeaminase family protein	A0A1V0SL93	Klosneuvirus	1.0e-15	26.3
WP_004441662.1\|2663302_2664670_-	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_012721374.1\|2665384_2666719_-	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_004441667.1\|2667095_2667749_+	DUF4397 domain-containing protein	NA	NA	NA	NA
WP_004441670.1\|2667886_2668363_-	copper amine oxidase N-terminal domain-containing protein	NA	NA	NA	NA
WP_004441673.1\|2668725_2672487_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.8e-28	23.4
WP_004441677.1\|2672692_2674033_-	MATE family efflux transporter	NA	NA	NA	NA
WP_012721096.1\|2674029_2676507_-	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	8.9e-48	38.6
2674854:2674872	attL	NA	NA	NA	NA
WP_004441682.1\|2676511_2676787_-	acyl carrier protein	NA	NA	NA	NA
WP_004441686.1\|2676792_2678331_-	acyl--CoA ligase	NA	NA	NA	NA
WP_004441689.1\|2678347_2679358_-	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_004441691.1\|2679341_2680223_-	bact protein	NA	NA	NA	NA
WP_004441694.1\|2680263_2682093_-	AMP-binding protein	A0A2K9L3I8	Tupanvirus	1.2e-54	29.5
WP_004441697.1\|2682133_2682646_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004441698.1\|2682649_2682898_-	acyl carrier protein	NA	NA	NA	NA
WP_004441700.1\|2682906_2683923_-	phosphoadenosine phosphosulfate reductase family protein	NA	NA	NA	NA
WP_004441702.1\|2683919_2685113_-	hypothetical protein	NA	NA	NA	NA
WP_012720386.1\|2685131_2685872_-	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_004441706.1\|2686337_2687339_-	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_004441708.1\|2687433_2688378_-	carbamate kinase	NA	NA	NA	NA
WP_004441711.1\|2688941_2690183_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	4.7e-98	52.1
WP_004441714.1\|2690356_2691127_+	threonine/serine exporter family protein	NA	NA	NA	NA
WP_004441721.1\|2691123_2691597_+	threonine/serine exporter family protein	NA	NA	NA	NA
WP_011986911.1\|2691677_2691947_-	metal-sensitive transcriptional regulator	NA	NA	NA	NA
WP_012721080.1\|2692145_2692970_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_012721307.1\|2693083_2693560_+	DUF4883 family protein	NA	NA	NA	NA
WP_012720607.1\|2693971_2698837_+	hypothetical protein	NA	NA	NA	NA
WP_012721259.1\|2698911_2700135_+	hypothetical protein	NA	NA	NA	NA
WP_024932087.1\|2700288_2701344_+	flavodoxin family protein	NA	NA	NA	NA
WP_039774087.1\|2701535_2702375_+	PHP domain-containing protein	NA	NA	NA	NA
WP_012704273.1\|2702904_2703138_-	hypothetical protein	NA	NA	NA	NA
WP_025776228.1\|2703325_2703913_-	DUF4352 domain-containing protein	A0A0A7RUM7	Clostridium_phage	1.1e-09	31.6
WP_025776229.1\|2704039_2704801_-	N-acetylmuramoyl-L-alanine amidase	I1TJX3	Clostridium_phage	3.4e-51	56.5
WP_012703930.1\|2704842_2705016_-	hypothetical protein	NA	NA	NA	NA
WP_012704941.1\|2705017_2705221_-\|bacteriocin	bacteriocin UviB	NA	NA	NA	NA
WP_012704381.1\|2705318_2705480_-	hypothetical protein	A0A0A8WJT8	Clostridium_phage	3.1e-10	60.0
WP_012703739.1\|2705479_2705776_-	hypothetical protein	J9QEB9	Clostridium_phage	1.3e-14	46.5
WP_012704885.1\|2707055_2708213_-	hypothetical protein	A0A0C5AMZ5	Paenibacillus_phage	2.0e-63	33.9
WP_061322224.1\|2708216_2709086_-\|tail	phage tail family protein	E2ELJ6	Clostridium_phage	4.3e-50	42.1
WP_061323309.1\|2709101_2713028_-\|tail	phage tail tape measure protein	M1PKM6	Streptococcus_phage	1.2e-91	52.0
WP_170015863.1\|2713084_2713297_-	hypothetical protein	A0A0A7RUE3	Clostridium_phage	9.6e-20	69.5
WP_012703788.1\|2713317_2713710_-	hypothetical protein	A0A0A7RUF5	Clostridium_phage	1.6e-36	64.6
WP_012705314.1\|2713767_2714349_-\|tail	tail protein	A0A0A7RUI3	Clostridium_phage	3.0e-79	73.2
WP_012704967.1\|2714412_2714769_-	hypothetical protein	A0A0A7S158	Clostridium_phage	3.3e-49	82.8
WP_012704313.1\|2714784_2715144_-	hypothetical protein	A0A0A7RUF1	Clostridium_phage	1.7e-48	84.7
WP_012704550.1\|2715144_2715513_-\|head	phage head closure protein	A0A0A7RUH8	Clostridium_phage	6.3e-35	63.8
WP_012705070.1\|2715502_2715796_-\|head,tail	phage gp6-like head-tail connector protein	A0A0A7RWM0	Clostridium_phage	2.9e-14	43.5
WP_012704630.1\|2715880_2717113_-\|capsid	phage major capsid protein	Q0SPK4	Clostridium_phage	4.1e-94	49.7
WP_012704826.1\|2717186_2717912_-\|protease	Clp protease ClpP	A0A0A7RUD3	Clostridium_phage	3.7e-103	86.6
WP_012705308.1\|2717904_2719155_-\|portal	phage portal protein	A0A0A7RUE7	Clostridium_phage	4.7e-183	79.5
WP_012703819.1\|2719198_2719381_-	hypothetical protein	A0A0A7RUH2	Clostridium_phage	1.7e-12	70.4
WP_012704014.1\|2719404_2721162_-\|terminase	terminase large subunit	A6M948	Geobacillus_virus	3.1e-119	43.2
WP_012704479.1\|2721162_2721648_-\|terminase	phage terminase small subunit P27 family	A6M947	Geobacillus_virus	8.9e-21	42.0
WP_012705231.1\|2721794_2722262_-	HNH endonuclease	Q0SPJ9	Clostridium_phage	8.0e-27	45.4
WP_012705667.1\|2722362_2724156_-	DUF2326 domain-containing protein	NA	NA	NA	NA
WP_041173639.1\|2724142_2724394_-	hypothetical protein	NA	NA	NA	NA
WP_012703787.1\|2724374_2724968_-	hypothetical protein	NA	NA	NA	NA
WP_012099883.1\|2724989_2725187_-	hypothetical protein	NA	NA	NA	NA
WP_012704448.1\|2725216_2725462_-	hypothetical protein	A0A2H4J8H2	uncultured_Caudovirales_phage	2.3e-09	45.7
WP_012342305.1\|2725586_2725769_-	hypothetical protein	NA	NA	NA	NA
WP_012705708.1\|2725837_2726050_-	hypothetical protein	NA	NA	NA	NA
WP_012705255.1\|2726126_2726447_-	hypothetical protein	NA	NA	NA	NA
WP_041173674.1\|2726477_2726666_-	hypothetical protein	NA	NA	NA	NA
WP_041173640.1\|2726672_2726927_-	hypothetical protein	NA	NA	NA	NA
WP_012705444.1\|2726968_2727556_-	hypothetical protein	NA	NA	NA	NA
WP_012704791.1\|2727851_2728307_-	hypothetical protein	NA	NA	NA	NA
WP_012704465.1\|2728334_2728631_-	hypothetical protein	NA	NA	NA	NA
WP_061323312.1\|2728930_2731825_-	hypothetical protein	NA	NA	NA	NA
WP_012703777.1\|2731981_2732146_-	hypothetical protein	NA	NA	NA	NA
WP_012704216.1\|2732504_2733641_-	hypothetical protein	NA	NA	NA	NA
WP_012704930.1\|2733686_2734640_-	hypothetical protein	NA	NA	NA	NA
WP_025775505.1\|2734716_2735145_-	hypothetical protein	NA	NA	NA	NA
WP_012704003.1\|2735563_2735722_-	hypothetical protein	NA	NA	NA	NA
WP_012704590.1\|2735785_2736205_-	hypothetical protein	NA	NA	NA	NA
WP_012705315.1\|2736640_2737297_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012705768.1\|2737428_2737569_-	hypothetical protein	NA	NA	NA	NA
WP_012704696.1\|2737579_2737909_-	hypothetical protein	NA	NA	NA	NA
WP_041173641.1\|2738134_2738338_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012704679.1\|2738548_2738758_-	hypothetical protein	NA	NA	NA	NA
WP_050760355.1\|2738900_2739446_+	restriction endonuclease	NA	NA	NA	NA
WP_012704818.1\|2739564_2740248_-	metallophosphoesterase	NA	NA	NA	NA
WP_012704210.1\|2740313_2740544_-	hypothetical protein	Q331U1	Clostridium_botulinum_C_phage	1.9e-13	54.3
WP_033045323.1\|2740557_2740893_-	hypothetical protein	NA	NA	NA	NA
WP_012705571.1\|2741595_2742528_-\|integrase	site-specific integrase	A7J266	Streptococcus_phage	2.6e-08	28.4
2750375:2750393	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3055782 : 3065227

Synechococcus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061323473.1\|3055782_3057282_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	5.5e-69	47.2
WP_003359899.1\|3057507_3058125_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.9e-26	39.3
WP_061323476.1\|3058251_3059247_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	4.5e-67	44.0
WP_050413611.1\|3059307_3060750_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	3.9e-56	32.1
WP_003359903.1\|3060847_3061552_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SLB8	Cyanophage	3.9e-41	43.7
WP_003359904.1\|3061551_3062031_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	5.7e-28	49.4
WP_024931859.1\|3062671_3065227_-	selenium-dependent xanthine dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	2.4e-11	33.1

DBSCAN-SWA_6

3202099 : 3234111

Clostridium_phage(77.78%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003360039.1\|3202099_3204727_-	DNA polymerase I	F8WQ35	Bacillus_phage	7.9e-63	34.7
WP_061323942.1\|3204744_3205869_-	chorismate synthase	A0A291AU41	Pandoravirus	6.9e-32	30.3
WP_024931547.1\|3206267_3207047_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	2.7e-88	63.4
WP_003360043.1\|3207193_3207388_-	hypothetical protein	NA	NA	NA	NA
WP_003358009.1\|3207406_3207661_-	hemolysin XhlA family protein	A0A0A7RTX0	Clostridium_phage	4.8e-26	70.9
WP_003360044.1\|3207821_3208610_-	hypothetical protein	A0A0A7RU33	Clostridium_phage	4.7e-27	34.2
WP_003360045.1\|3208642_3209467_-	discoidin domain-containing protein	A0A0A7RU33	Clostridium_phage	5.6e-15	28.4
WP_003360047.1\|3210351_3211131_-	discoidin domain-containing protein	NA	NA	NA	NA
WP_003360048.1\|3211133_3212051_-	hypothetical protein	NA	NA	NA	NA
WP_024931548.1\|3212083_3213169_-	hypothetical protein	A0A0A7RU66	Clostridium_phage	3.0e-141	70.4
WP_061323944.1\|3213180_3214179_-	hypothetical protein	A0A0A7RW91	Clostridium_phage	4.4e-139	72.0
WP_003360052.1\|3214190_3214445_-	hypothetical protein	A0A0A7S0T0	Clostridium_phage	1.1e-33	81.0
WP_003360053.1\|3214450_3216346_-	hypothetical protein	A0A0A7RU09	Clostridium_phage	4.3e-119	52.6
WP_061323946.1\|3216360_3217599_-	hypothetical protein	A0A0A7RU28	Clostridium_phage	4.8e-196	81.1
WP_024931550.1\|3217621_3218602_-	hypothetical protein	A0A0A7RU61	Clostridium_phage	1.0e-111	61.3
WP_024931551.1\|3218603_3219953_-	caspase family protein	A0A0A7RW86	Clostridium_phage	6.0e-75	74.1
WP_024931552.1\|3219967_3220309_-	hypothetical protein	A0A0A7S0S4	Clostridium_phage	2.1e-16	55.7
WP_061316639.1\|3220321_3221407_-	hypothetical protein	NA	NA	NA	NA
WP_021135630.1\|3221393_3221828_-	hypothetical protein	NA	NA	NA	NA
WP_021135631.1\|3221840_3223382_-	hypothetical protein	A0A0A7RU22	Clostridium_phage	5.8e-05	43.5
WP_003483832.1\|3223545_3223788_-	hypothetical protein	A0A0A7RW80	Clostridium_phage	4.4e-21	67.6
WP_003357967.1\|3223747_3224164_-	hypothetical protein	A0A0A7S0S0	Clostridium_phage	9.0e-46	71.2
WP_021135633.1\|3224178_3225066_-	hypothetical protein	A0A0A7RTZ9	Clostridium_phage	8.2e-121	75.2
WP_024931553.1\|3225070_3225490_-	hypothetical protein	A0A0A7RU17	Clostridium_phage	1.8e-57	71.9
WP_061323948.1\|3225495_3225843_-	hypothetical protein	A0A0A7RU51	Clostridium_phage	4.3e-33	60.6
WP_021135635.1\|3225847_3226213_-	hypothetical protein	A0A0A7RW73	Clostridium_phage	2.9e-32	54.5
WP_024931555.1\|3226212_3226497_-	hypothetical protein	A0A0A7S0R4	Clostridium_phage	2.0e-25	61.2
WP_024931556.1\|3227183_3227705_-	hypothetical protein	A0A0A7RVS1	Clostridium_phage	1.4e-35	50.0
WP_061323950.1\|3227819_3228140_-	hypothetical protein	NA	NA	NA	NA
WP_061323977.1\|3228196_3228997_-	ATP-binding protein	S5W9L4	Leptospira_phage	2.8e-19	33.0
WP_045904639.1\|3228986_3229892_-	phage replisome organizer N-terminal domain-containing protein	A8ASN4	Listeria_phage	1.9e-40	39.5
WP_003358080.1\|3229985_3230198_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003357707.1\|3230259_3230469_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_021135437.1\|3230659_3231070_+	helix-turn-helix domain-containing protein	A0A0A7RUJ5	Clostridium_phage	1.0e-09	56.2
WP_003357837.1\|3231371_3231521_+	hypothetical protein	NA	NA	NA	NA
WP_061323953.1\|3232623_3234111_+	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	7.4e-66	38.1

Anti-CRISPR protein detection

Acr_ID: NZ_CP013845.1|WP_012704003.1|2735563_2735722_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP013845.1|WP_012704003.1|2735563_2735722_-|hypothetical-protein

2735563_2735722_-

52 aa aa

2649762-2742528

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP013844_1	TypeI-B	1.2\|33196\|36\|NZ_CP013844\|PILER-CR	33196-33231	36	2737020-2737055	0

1. spacer 1.2|33196|36|NZ_CP013844|PILER-CR matches to NZ_CP013845 position: 2737020-2737055, mismatch: 0

cgtctaattggatcaaaaactctattaactttttga	CRISPR spacer
cgtctaattggatcaaaaactctattaactttttga	Protospacer
************************************

2. NZ_CP013844

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP013844_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013844_1

33100-33654

TypeI-B

Consensus_repeat	Method
GTCATCCAACAATATAAGATATTTTTAAAT	PILER-CR
ATCCAACAATATAAGATATTTTTAAAT	CRISPRCasFinder
ATNNNANAANATAAGATNTTTTTAAAT	CRT
ATCCAACAATATAAGATATTTTTAAAT	CRISPRCasFinder

8 spacers

cas5,cas7b,cas8b1,cas3

The CRISPR arrays of NZ_CP013844_1

>merge|NZ_CP013844|1|33100-33654|PILER-CR,CRISPRCasFinder,CRT,CRISPRCasFinder
GTCATCCAACAATATAAGATATTTTTAAATAATTACTCAAGGAAAAATACTGCTTTAGAAAACTTCGTCATCCAACAATATAAGATATTTTTAAATCGTCTAATTGGATCAAAAACTCTATTAACTTTTTGAGTTATCCAACAATATAAGATATTTTTAAATTAATTATTTGTTGCAATCTATATATAATAAATATGAGTTATCCAACAATATAAGATATTTTTAAATATGAATGACAATCGCTATACATGTAGAACAATAGAGTTATCAAATAATATAAGATGTTTTTAAACTCGTATAGTTTTTCTGTTAAAGGAATTTTTCTTTTGTTATGAATATAGCATATGATGTTTTTAAATTACGATGCTGACGCCTCTGAAATTGAAATAGTTACAGTTATTAAATAATATAAGATATTTTTAAATTAGAATATGGAATAAGACATTCTTTAAAGATGATGAGTTATAATAAAACATTATATGTTTTTAAATTTTAATAGAATAATAAGTTTTCAAGCCTTTAAGAGTTATAATACAACATTGTGTGTTTTTAAAT

>NZ_CP013844|1|1|33100-33327|PILER-CR
GTCATCCAACAATATAAGATATTTTTAAAT	AATTACTCAAGGAAAAATACTGCTTTAGAAAACTTC
GTCATCCAACAATATAAGATATTTTTAAAT	CGTCTAATTGGATCAAAAACTCTATTAACTTTTTGA
GTTATCCAACAATATAAGATATTTTTAAAT	TAATTATTTGTTGCAATCTATATATAATAAATATGA
GTTATCCAACAATATAAGATATTTTTAAAT

>NZ_CP013844|1|1|33103-33393|CRISPRCasFinder
ATCCAACAATATAAGATATTTTTAAAT	AATTACTCAAGGAAAAATACTGCTTTAGAAAACTTCGTC
ATCCAACAATATAAGATATTTTTAAAT	CGTCTAATTGGATCAAAAACTCTATTAACTTTTTGAGTT
ATCCAACAATATAAGATATTTTTAAAT	TAATTATTTGTTGCAATCTATATATAATAAATATGAGTT
ATCCAACAATATAAGATATTTTTAAAT	ATGAATGACAATCGCTATACATGTAGAACAATAGAGTT
ATCAAATAATATAAGATGTTTTTAAACTCGTATAGTTTTTCTGTTAAAGGAATTTTTCTTTTGTTATGAATATAGCATATGATGTTTTTAAATTACGATGCTGACGCCTCTGAAATTGAAATAGTTACAGTTATTAAATAATATAAGATATTTTTAAAT	TAGAATATGGAATAAGACATTCTTTAAAGATGATGAGTT


>NZ_CP013844|1|1|33103-33654|CRT
ATCCAACAATATAAGATATTTTTAAAT	AATTACTCAAGGAAAAATACTGCTTTAGAAAACTTCGTC
ATCCAACAATATAAGATATTTTTAAAT	CGTCTAATTGGATCAAAAACTCTATTAACTTTTTGAGTT
ATCCAACAATATAAGATATTTTTAAAT	TAATTATTTGTTGCAATCTATATATAATAAATATGAGTT
ATCCAACAATATAAGATATTTTTAAAT	ATGAATGACAATCGCTATACATGTAGAACAATAGAGTT
ATCAAATAATATAAGATGTTTTTAAAC	TCGTATAGTTTTTCTGTTAAAGGAATTTTTCTTTTGTTA
TGAATATAGCATATGATGTTTTTAAAT	TACGATGCTGACGCCTCTGAAATTGAAATAGTTACAGTT
ATTAAATAATATAAGATATTTTTAAAT	TAGAATATGGAATAAGACATTCTTTAAAGATGATGAGTT
ATAATAAAACATTATATGTTTTTAAAT	TTTAATAGAATAATAAGTTTTCAAGCCTTTAAGAGTT
ATAATACAACATTGTGTGTTTTTAAAT

>NZ_CP013844|1|2|33498-33590|CRISPRCasFinder
	AATTACTCAAGGAAAAATACTGCTTTAGAAAACTTCGTC
ATCCAACAATATAAGATATTTTTAAAT	CGTCTAATTGGATCAAAAACTCTATTAACTTTTTGAGTT
ATCCAACAATATAAGATATTTTTAAAT	TAATTATTTGTTGCAATCTATATATAATAAATATGAGTT
ATCCAACAATATAAGATATTTTTAAAT	ATGAATGACAATCGCTATACATGTAGAACAATAGAGTT
ATCAAATAATATAAGATGTTTTTAAACTCGTATAGTTTTTCTGTTAAAGGAATTTTTCTTTTGTTATGAATATAGCATATGATGTTTTTAAATTACGATGCTGACGCCTCTGAAATTGAAATAGTTACAGTTATTAAATAATATAAGATATTTTTAAAT	TAGAATATGGAATAAGACATTCTTTAAAGATGATGAGTT
ATAATAAAACATTATATGTTTTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013844.1\|WP_051498540.1\|36972_37560_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP013844.1\|WP_024931653.1\|37585_38086_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|372510
NZ_CP013844.1\|WP_024931657.1\|31255_32185_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP013844.1\|WP_024932251.1\|40167_41229_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061328810.1\|28293_28530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932253.1\|42042_43329_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222893
NZ_CP013844.1\|WP_024931656.1\|32186_32936_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP013844.1\|WP_024931655.1\|33770_36236_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP013844.1\|WP_024931665.1\|24753_25029_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931662.1\|26663_27455_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931661.1\|27658_28111_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_154695167.1\|36705_36882_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061328811.1\|38714_40184_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932249.1\|38132_38585_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931658.1\|29480_31253_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NZ_CP013844.1\|WP_024932252.1\|41616_41898_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061332053.1\|25549_26491_+\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378235
NZ_CP013844.1\|WP_024931664.1\|25212_25407_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931659.1\|28720_29467_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273848
NZ_CP013844.1\|WP_061328812.1\|43708_44893_+\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|370826

Protein	Function_ID	Function_description	E-value
NZ_CP013844.1\|WP_051498540.1\|36972_37560_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.85927e-26
NZ_CP013844.1\|WP_024931653.1\|37585_38086_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|372510	pfam13176, TPR_7, Tetratricopeptide repeat.	0.00142647
NZ_CP013844.1\|WP_024931657.1\|31255_32185_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.65004e-17
NZ_CP013844.1\|WP_061328812.1\|43708_44893_+\|replication-initiator-protein-A	gnl\|CDD\|370826	pfam10134, RPA, Replication initiator protein A. Members of this family of bacterial proteins are single-stranded DNA binding proteins that are involved in DNA replication, repair and recombination.	9.56918e-06
NZ_CP013844.1\|WP_024931656.1\|32186_32936_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	8.29076e-27
NZ_CP013844.1\|WP_024931659.1\|28720_29467_+\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.46554e-07
NZ_CP013844.1\|WP_061332053.1\|25549_26491_+\|Rha-family-transcriptional-regulator	gnl\|CDD\|378235	pfam09669, Phage_pRha, Phage regulatory protein Rha (Phage_pRha). Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.	3.67602e-07
NZ_CP013844.1\|WP_024931655.1\|33770_36236_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	6.31332e-26
NZ_CP013844.1\|WP_024932253.1\|42042_43329_+\|hypothetical-protein	gnl\|CDD\|222893	PHA02587, 30, DNA ligase; Provisional.	1.84323e-49

>NZ_CP013844.1|WP_024931656.1|32186_32936_+|type-I-B-CRISPR-associated-protein-Cas5
MECLKFDLGGKTAFFKKPEINDVNFTFSNIHKIATLGMIGAIIGLNGRQQSKENGKIKFYETLKSIELSIVPFSPYFSKTYTIFNNATGFANKSASKHGATQNIKQQWLTNPKWTIYLKQGALDNTIWGKIKKYFLQGNYVYEPYLGGRPHIANITNVNLIDIDNIKNKEDIYKVDSLVKYNEIIDIDSQVYENCEDEYSYCLKEYTPIKLDDRGLYITEKMLHTNYEIYEVKNTNNFYKYNNNILYFI
>NZ_CP013844.1|WP_024931657.1|31255_32185_+|type-I-CRISPR-associated-protein-Cas7
MKMNNRVYGVTGIGVRNNNFNAGFDKTPKTLSNGTIFGAHQALKYPNRVFWDKLGEKVFYLKSYTEDGNVKKINERFQELFQMEDKDIQAVKSNLFKCVDVMNHGAAYTGNVSVDIRGAVQINNGDNKYELTTIDIFNILSPFGNKNSEKDTKQSSLGDTVVTDEAHYVYSINVNPFEYDKYIGTIEGFEGYTREAYDLFKEASLIAVSDYNSASKTGCQNEFTIFVELKDEMQGKFNLNELGQYIKVYNSENSNKRIYDLTILTEILNSGNISKDIKSIEIYYNPYTLELLENIENAKRFNIITREEI
>NZ_CP013844.1|WP_024931658.1|29480_31253_+|hypothetical-protein
MFKELIDEIGYNNILEYCENANLQNGIYIKINKDGNIEDKNIIEIENDKKDIENIELINWFKQRNCYSNYIDSNKAIVQRGKGVKTPKIVTSCNCYSVFFNVATILKNSKKMEMSLDKYCKNMITEYFDALINNIMNDKNGLSSIFKSNNIKSYMKKNKTTITKMIKKFFMNEYLLAQDKHRKKCINETKEILIQNIFVLINKLSNVKNIDKKKIKIFIDSEVDDYKKEYLLYLKPRIFLNNENNLILDDKIYGLSSELFTINSKKPLLKTNANLTDIPCLISIKGAIKYRNLIVYLKGNLSKTRELGYDLIFDKDGINVFDIIPFNKKDKLELKPLIIKDYLNKSFDTVEINNKKSLENSFNYFLDGNLYSNKINDNSKAKSFVVMYRDIISNYVYKDIDRDFLYALPKILNQLLNANLNPKKNVFDIMKCFNFRLSLLEYFKNNEKGEVIMKLNNDLKERLRDINTFTINSREEFIYICGQLGYYLNSRSKASPENKKMMLVNTYINCNNIELLKRKLQQDISKYSYDIQLNNDRFKKIIEQISLFKFDNNSISSSEKDYLLAGLFGNNLVYYEKKNNNKNNNNMEGK
>NZ_CP013844.1|WP_024931659.1|28720_29467_+|hypothetical-protein
MLNKNYELRIKIYLLRDIPLEDANEILSKAIDYTMLLNKNLRPIHTNKGFKHYSFSTPYPVESDRVYKKDRIYSFMIRDYSKQKIKDFQSVFSKLRLNEFVVLTTEIKEYHKKRISHIYTITPTVLTLLEEEVPDKLKTIKTKQKCWVKGCNHLLLIDRIENNLIKKYKDLTQKDIVVNNDIIESVEITNKVPIKINYKDSAIIGNKFKITFAQNELTQEIANLSVVEGILEKNSSLGCGFVKPAFVE
>NZ_CP013844.1|WP_061328810.1|28293_28530_+|hypothetical-protein
MTNSLKNTIDTDKNREAVNRAKKAIKQYELELKSLDIQMTKNNIILDKYINSDEYKDNLKEIQELEDRERELDKESKK
>NZ_CP013844.1|WP_024931661.1|27658_28111_+|hypothetical-protein
MEKIKFIYIDVEEETKEIKQLLDKGLIKYFYGKDSNEPDFIFLSENEDIIKSSITSEYRISNILRQLIIMFDGSNINIRNLWGDEINLDYKTLLNLMKENLNSYLSEDTQELIYQAEIPADKLTNIINQNGKEQLQMQIEDLLMESKKVI
>NZ_CP013844.1|WP_024931662.1|26663_27455_+|hypothetical-protein
MEIKNIQQLIELKKLKWSNPYTQRDFEVNSIDEFKYLLENYLNKFAFGVTYNTFKYTIFKEDDYIYIRNNDTYKFKNGYTGNITEEYTLKENSIDNIIDFIISSPDKNDKRRTRIKFIYIDVDDITDEMKQLLDKGLMKYFYGKNSCEPEFIYLAENEHIIKNTLTAEYCILDFASKLSEIFDCTDMTVRNIWNDEISFYHGRIEDLISDNLYGYIPESKQKEIFNTENPSNKLRTIFNEIGREQLRIQIKDLLKEINRAEFI
>NZ_CP013844.1|WP_061332053.1|25549_26491_+|Rha-family-transcriptional-regulator
MKNKEFLEKLNMKEMISTQINSWELMLKKKGLKDKTIERKLNNLIYFYMHLTALRKDKERIKIDNISNIAFEYVRDGYFSEDNIDNEGCYGYRRNIYCNLREGFNFIYQGYFKNKIEVINDLIEEQKEVLEDVSKNKWFNVVGIKDDRETIQTKIIEELGLKVYFDKENNPYVLSHETAELIGKKHKDVTKAIRLILDRFTRAKKIALVENVDISMIEDHYTYNTNNGGTKDVITYRLSKDLVINYILGMSGDKYFDFKIKYQSAFNYIEREYKKLLEEHSTLKDSFLKMYNNIRKRNRDLLIKEHNKKAKSK
>NZ_CP013844.1|WP_024931664.1|25212_25407_+|hypothetical-protein
MNKTLKLKQFNNKIYLYNRKNPVTVGKEIKIIFHDAIVFSGQVTKENISEIQKMITYSDNYIIN
>NZ_CP013844.1|WP_024931665.1|24753_25029_+|hypothetical-protein
MEILSHNSDGKKDIKGIERCKKVYNSTISNKSYIKVNVLGKTWRVKKEAQNKWLKVAKVEDLIRDNLNDVLGALSVGITGVLIYFIMAMYY
>NZ_CP013844.1|WP_024931655.1|33770_36236_+|CRISPR-associated-helicase/endonuclease-Cas3
MDKYLSRPNEDLIIHLNLTINNYNNYCKTNNLDKIIKNIISKLLQENNIKNEEASKQVYEMFINSIWLHDIGKINPYFQAYISNPNFKDYEFNNENKKHSILSSLIYLNIYYGKIKDVIYSKNRRENKNIKILLYDLLISFAYCISKHHTSLKDFDSIIFFNKLDNTVIQNNLLINNLNIDKEFIKKLKQINYKDVVYTNEFTKYILIKLCYSSIVTCDFLAVYNFYNKKQFHTNAINKNKLKQFNDKYNNLDIIKSIRNYPYNKDKLGKLNKMRTEMFLESESNLMKCISDNIFYLEAPTGSGKSNTSLNLALNILNNSKQFNKIISVNPYNAISEQTYNNTRNSLLIDDKDVVLINSQTEIIESDIEDETHYSKDFLDNQLLNYPVSIISHVKLFKALFSNNRIDNLMLFNIINSVIIIDEVQSYKNNLWIHIINSFKQFSDLLNFKIIIMSATLPKMDCLLEDKTYISNLIHNKNYYYNYFKNRVSLNFNLLNIKQFNKNILCDKINIEIKNNKRILVEFIKNKTANEIYNYYKQKFKSADYLVFNITSNCNSLYKQNVLKLINEKDDKNNFVNQKILVICTQTIEAGVDIDMDVGFKDISLLDSDEQFCGRINRNFKREGVVYFFHLDKITDVYKDDYRCERNLLNEQWQHLLITKQFNKFYELNYKRLLEEEKLNKDYYTYKNNLRTIQFEEIDKTMTLIDEQNCNLYLYCKLKLKDITIDSKNMFNKYIELKKDCNMDYSKKMIKLSKLKKWLGLFTYKFKVFNKNKPSIYNDYIDNYYILENPNEYIDIKEGFINEFSLFNMNKYIEDCNGLFL
>NZ_CP013844.1|WP_154695167.1|36705_36882_-|hypothetical-protein
MIERIQCQQILLNYFKLFCDTQHIVLDLLEMYICCGQDTIKEGFYIKLFEVKTLYVIL
>NZ_CP013844.1|WP_051498540.1|36972_37560_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MLNNKIFMKRRGDIVYVDLGNPKGTNQGGKRPCIIVPNNKCTEHSTSIQIIPITSKLNKKRLPTHIFIKKDELNGLNEDSLILVEQTDLISTSQILSVVGRASDEIMRKVNAKLKIQFDLDKPDVNRIKAKIKTLKEMESYILKHNENSEELLNILKFQVSDFRDYCQEYNLNCSQYYVSKFNIINRYFQRNIAA
>NZ_CP013844.1|WP_024931653.1|37585_38086_+|tetratricopeptide-repeat-protein
MVYTLLKMKIREMYLEKKYEECNKKLTDLYRELIRDNQITLAEQNQLIWYYYFYKSNIFKNQNNLKDSLSFCLKSFRYITFKDKFNTEYKGTLFLLANIYKELNKKQKAIKTYEYLLRITKDKQYEMIFENINNLRQNSNVITFTNKQNKKYDSNKENNFKFCCYF
>NZ_CP013844.1|WP_024932249.1|38132_38585_+|hypothetical-protein
MKNKIRFIHDNQIKTGYIKTNLNKFKKEFILVEKGKNRYRIPIENLITTENELEINKKLLKHQIDNYISKYNLTIQWVNDTLKVSSILDEWFIEPSKNNLLILQHINKKNKDAKGKFHKQGIFYNYFSALRHIAEHDKTKLGIDFSNKSA
>NZ_CP013844.1|WP_061328811.1|38714_40184_+|hypothetical-protein
MIENKDYNYDRLIREITGCLSLKQFLMKKPFVIKELENKVNEERINNLFNQDIQIDMLDTRELYLITETFYKMLLDEEFISKLNEFQQQLQKDLNPELYFTEDEIRQYKNSVLPVEEEQDFKTVVFKNVKFMKEGIYSTVDDFNYILDLREKGILFYNINCQRETEKYEWRGTYVEKAKVFSKSIKEISESMYQDKYIPTYIAINVPSNGEEDFHVIDKENGLYDIIIKINKNTSLNLIDGNHRTTGGSLARNMCRRKGKEFLLNMGIQIMNLDPSSARQYIFQESKKNPLDETLTKAMEKTIENEIADYMNKGESPLAGKLGRELKDVKTLNKLTPLYVFAEGLKHFELDELDLIRKNKVKRFLKDFFNCILSFHKDKRRDRELSIEDMLKNKKLKEKKSEEEGYELNMNMFRGYLYIAAKLFNDPNWIEKIDTILKKIDYKKGGALEDMHLFKNEMSKTNIKKLEEYLENILSEVEESGENENVRKN
>NZ_CP013844.1|WP_024932251.1|40167_41229_+|hypothetical-protein
MSEKIRDFTSLNKLYFRELDERKKEYINFLKNEQDLQDITVDNYTNQIYKIRAFEEIIDRDRTIEYFTLDEISKLLENMTFSSESSAIAYKNRILDYLKFCTEHYGIQKDIGLLNTISQKEFIQGLVNKRLKYLKYVTEGTLYEAVQDLVNPQDRLMALLIYEGVKGTNHADLINIKKEQYDKENKILEYIEQDTGKTKQLRCNEFLSDEIEKTILSDTYYFKNGKGTGRHDMSDIVNSPYLVAPTAQLNARMNNYSGQQVYGQTIQSRILKIFKHFLDINGQHITVQSLYHSGIVNRMVKLTEEKYAGQKLKKVDFVKYIEQNEKLKLQAGYRLYDIYENLYNLFKNDIISF
>NZ_CP013844.1|WP_024932252.1|41616_41898_+|hypothetical-protein
MEVKLMNYLKGNKGYGITISEIGGDEKFLEDMCYKHNTNLKRIEILGKNEFLEMDKYIIKMENIVNIEEDISNISIFTESETENKEIIIENWD
>NZ_CP013844.1|WP_024932253.1|42042_43329_+|hypothetical-protein
MKNNLKECLEILKSIGNDSSRIAKETILKENKDNQLLKDILFFLYNPYIVTGISTKKLNKKVKLEVDNKLNTIIDVMDFLKTNNTGTDEHIKVIQNWINNQDLQYQDILKQLVTKSLKIGITSKTINKIHKNFIPEFNVMLAEKYHENINRVKGKFIITTKLDGNRMVLVKENGAIKTFSRQGQLIEGLIDIIEDAKQLQDNMVYDGEILLKNDKNLDSKQLFQETQKIIRKKDIKKTNLIFNIFDMMPLDEFKQGVSINDTLTRKNQLHDILESLETNWVKEVPMLYVGEDINKIDELLNIAVQNGEEGIMINLVDSKYQCKRTKDLLKVKIMNSSDCKIIGYEEGTGRNEGVLGAFIIDYKGHNVKVGSGYTDEDRKMFWENKDAFIEKIIEVQYFEETKNQNGGISLRFPVYKCIRNDKIEPSYF
>NZ_CP013844.1|WP_061328812.1|43708_44893_+|replication-initiator-protein-A
MDKKEEEQEVETISLKSNQSINESNLMVIPFISMKKTKVKVLERYWISNGVRRGIKVVGSGEHGCPTIAELDVLLALFRILIKNVGFKYEYNRTTGKVSLPKTIHFTYQELSKELGYKTYGGALKKKLENSVKCLNEATIYSDLGLRDVEAGDYIYDFEGEDSFRILEDYKSFSYTKRKKKGEKIGDAKQVKSMQSVTISDFFFKNICNNYFKIYNYNQYLMLTKGVAKKLYLLLNQWSRGYEKYLTYIKLYDMLSLDVAKNENNEEIDKKKAYYYNRIIKDALDELTTVKFIQDYDIRTNDGINLIFNINKRNKNRFLDKYNDEKEIINRLQEIGLTLKEWTKYYRLDNQEYVKALLRYVDYKIENKNDIRDVLKFTIDGLKSENYDVKEFIG

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Crispr_ID: NZ_CP013844_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013844_2

36376-36474

TypeI-B

Consensus_repeat	Method
ATTATCACATAACATATAATGTTTTTAAATTAT	CRISPRCasFinder

1 spacers

cas3,cas5,cas7b,cas8b1

The CRISPR arrays of NZ_CP013844_2

>merge|NZ_CP013844|2|36376-36474|CRISPRCasFinder
ATTATCACATAACATATAATGTTTTTAAATTATAAAGCAATAGCACTTTCAATGTCTTTTTGCTTATTATCATATAACATATAATGTTTTTAAATTATG

>NZ_CP013844|2|3|36376-36474|CRISPRCasFinder
ATTATCACATAACATATAATGTTTTTAAATTAT	AAAGCAATAGCACTTTCAATGTCTTTTTGCTT
ATTATCATATAACATATAATGTTTTTAAATTATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013844.1\|WP_051498540.1\|36972_37560_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP013844.1\|WP_024931653.1\|37585_38086_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|372510
NZ_CP013844.1\|WP_024931657.1\|31255_32185_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP013844.1\|WP_024932310.1\|45200_45554_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932251.1\|40167_41229_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061328810.1\|28293_28530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932253.1\|42042_43329_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222893
NZ_CP013844.1\|WP_024931656.1\|32186_32936_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP013844.1\|WP_024931655.1\|33770_36236_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP013844.1\|WP_024931662.1\|26663_27455_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931661.1\|27658_28111_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_154695167.1\|36705_36882_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061328811.1\|38714_40184_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932249.1\|38132_38585_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931658.1\|29480_31253_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NZ_CP013844.1\|WP_024932252.1\|41616_41898_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061332053.1\|25549_26491_+\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378235
NZ_CP013844.1\|WP_024931664.1\|25212_25407_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931659.1\|28720_29467_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273848
NZ_CP013844.1\|WP_061328812.1\|43708_44893_+\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|370826

Protein	Function_ID	Function_description	E-value
NZ_CP013844.1\|WP_051498540.1\|36972_37560_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.85927e-26
NZ_CP013844.1\|WP_024931653.1\|37585_38086_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|372510	pfam13176, TPR_7, Tetratricopeptide repeat.	0.00142647
NZ_CP013844.1\|WP_024931657.1\|31255_32185_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.65004e-17
NZ_CP013844.1\|WP_061328812.1\|43708_44893_+\|replication-initiator-protein-A	gnl\|CDD\|370826	pfam10134, RPA, Replication initiator protein A. Members of this family of bacterial proteins are single-stranded DNA binding proteins that are involved in DNA replication, repair and recombination.	9.56918e-06
NZ_CP013844.1\|WP_024931656.1\|32186_32936_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	8.29076e-27
NZ_CP013844.1\|WP_024931655.1\|33770_36236_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	6.31332e-26
NZ_CP013844.1\|WP_061332053.1\|25549_26491_+\|Rha-family-transcriptional-regulator	gnl\|CDD\|378235	pfam09669, Phage_pRha, Phage regulatory protein Rha (Phage_pRha). Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.	3.67602e-07
NZ_CP013844.1\|WP_024931659.1\|28720_29467_+\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.46554e-07
NZ_CP013844.1\|WP_024932253.1\|42042_43329_+\|hypothetical-protein	gnl\|CDD\|222893	PHA02587, 30, DNA ligase; Provisional.	1.84323e-49

>NZ_CP013844.1|WP_024931655.1|33770_36236_+|CRISPR-associated-helicase/endonuclease-Cas3
MDKYLSRPNEDLIIHLNLTINNYNNYCKTNNLDKIIKNIISKLLQENNIKNEEASKQVYEMFINSIWLHDIGKINPYFQAYISNPNFKDYEFNNENKKHSILSSLIYLNIYYGKIKDVIYSKNRRENKNIKILLYDLLISFAYCISKHHTSLKDFDSIIFFNKLDNTVIQNNLLINNLNIDKEFIKKLKQINYKDVVYTNEFTKYILIKLCYSSIVTCDFLAVYNFYNKKQFHTNAINKNKLKQFNDKYNNLDIIKSIRNYPYNKDKLGKLNKMRTEMFLESESNLMKCISDNIFYLEAPTGSGKSNTSLNLALNILNNSKQFNKIISVNPYNAISEQTYNNTRNSLLIDDKDVVLINSQTEIIESDIEDETHYSKDFLDNQLLNYPVSIISHVKLFKALFSNNRIDNLMLFNIINSVIIIDEVQSYKNNLWIHIINSFKQFSDLLNFKIIIMSATLPKMDCLLEDKTYISNLIHNKNYYYNYFKNRVSLNFNLLNIKQFNKNILCDKINIEIKNNKRILVEFIKNKTANEIYNYYKQKFKSADYLVFNITSNCNSLYKQNVLKLINEKDDKNNFVNQKILVICTQTIEAGVDIDMDVGFKDISLLDSDEQFCGRINRNFKREGVVYFFHLDKITDVYKDDYRCERNLLNEQWQHLLITKQFNKFYELNYKRLLEEEKLNKDYYTYKNNLRTIQFEEIDKTMTLIDEQNCNLYLYCKLKLKDITIDSKNMFNKYIELKKDCNMDYSKKMIKLSKLKKWLGLFTYKFKVFNKNKPSIYNDYIDNYYILENPNEYIDIKEGFINEFSLFNMNKYIEDCNGLFL
>NZ_CP013844.1|WP_024931656.1|32186_32936_+|type-I-B-CRISPR-associated-protein-Cas5
MECLKFDLGGKTAFFKKPEINDVNFTFSNIHKIATLGMIGAIIGLNGRQQSKENGKIKFYETLKSIELSIVPFSPYFSKTYTIFNNATGFANKSASKHGATQNIKQQWLTNPKWTIYLKQGALDNTIWGKIKKYFLQGNYVYEPYLGGRPHIANITNVNLIDIDNIKNKEDIYKVDSLVKYNEIIDIDSQVYENCEDEYSYCLKEYTPIKLDDRGLYITEKMLHTNYEIYEVKNTNNFYKYNNNILYFI
>NZ_CP013844.1|WP_024931657.1|31255_32185_+|type-I-CRISPR-associated-protein-Cas7
MKMNNRVYGVTGIGVRNNNFNAGFDKTPKTLSNGTIFGAHQALKYPNRVFWDKLGEKVFYLKSYTEDGNVKKINERFQELFQMEDKDIQAVKSNLFKCVDVMNHGAAYTGNVSVDIRGAVQINNGDNKYELTTIDIFNILSPFGNKNSEKDTKQSSLGDTVVTDEAHYVYSINVNPFEYDKYIGTIEGFEGYTREAYDLFKEASLIAVSDYNSASKTGCQNEFTIFVELKDEMQGKFNLNELGQYIKVYNSENSNKRIYDLTILTEILNSGNISKDIKSIEIYYNPYTLELLENIENAKRFNIITREEI
>NZ_CP013844.1|WP_024931658.1|29480_31253_+|hypothetical-protein
MFKELIDEIGYNNILEYCENANLQNGIYIKINKDGNIEDKNIIEIENDKKDIENIELINWFKQRNCYSNYIDSNKAIVQRGKGVKTPKIVTSCNCYSVFFNVATILKNSKKMEMSLDKYCKNMITEYFDALINNIMNDKNGLSSIFKSNNIKSYMKKNKTTITKMIKKFFMNEYLLAQDKHRKKCINETKEILIQNIFVLINKLSNVKNIDKKKIKIFIDSEVDDYKKEYLLYLKPRIFLNNENNLILDDKIYGLSSELFTINSKKPLLKTNANLTDIPCLISIKGAIKYRNLIVYLKGNLSKTRELGYDLIFDKDGINVFDIIPFNKKDKLELKPLIIKDYLNKSFDTVEINNKKSLENSFNYFLDGNLYSNKINDNSKAKSFVVMYRDIISNYVYKDIDRDFLYALPKILNQLLNANLNPKKNVFDIMKCFNFRLSLLEYFKNNEKGEVIMKLNNDLKERLRDINTFTINSREEFIYICGQLGYYLNSRSKASPENKKMMLVNTYINCNNIELLKRKLQQDISKYSYDIQLNNDRFKKIIEQISLFKFDNNSISSSEKDYLLAGLFGNNLVYYEKKNNNKNNNNMEGK
>NZ_CP013844.1|WP_024931659.1|28720_29467_+|hypothetical-protein
MLNKNYELRIKIYLLRDIPLEDANEILSKAIDYTMLLNKNLRPIHTNKGFKHYSFSTPYPVESDRVYKKDRIYSFMIRDYSKQKIKDFQSVFSKLRLNEFVVLTTEIKEYHKKRISHIYTITPTVLTLLEEEVPDKLKTIKTKQKCWVKGCNHLLLIDRIENNLIKKYKDLTQKDIVVNNDIIESVEITNKVPIKINYKDSAIIGNKFKITFAQNELTQEIANLSVVEGILEKNSSLGCGFVKPAFVE
>NZ_CP013844.1|WP_061328810.1|28293_28530_+|hypothetical-protein
MTNSLKNTIDTDKNREAVNRAKKAIKQYELELKSLDIQMTKNNIILDKYINSDEYKDNLKEIQELEDRERELDKESKK
>NZ_CP013844.1|WP_024931661.1|27658_28111_+|hypothetical-protein
MEKIKFIYIDVEEETKEIKQLLDKGLIKYFYGKDSNEPDFIFLSENEDIIKSSITSEYRISNILRQLIIMFDGSNINIRNLWGDEINLDYKTLLNLMKENLNSYLSEDTQELIYQAEIPADKLTNIINQNGKEQLQMQIEDLLMESKKVI
>NZ_CP013844.1|WP_024931662.1|26663_27455_+|hypothetical-protein
MEIKNIQQLIELKKLKWSNPYTQRDFEVNSIDEFKYLLENYLNKFAFGVTYNTFKYTIFKEDDYIYIRNNDTYKFKNGYTGNITEEYTLKENSIDNIIDFIISSPDKNDKRRTRIKFIYIDVDDITDEMKQLLDKGLMKYFYGKNSCEPEFIYLAENEHIIKNTLTAEYCILDFASKLSEIFDCTDMTVRNIWNDEISFYHGRIEDLISDNLYGYIPESKQKEIFNTENPSNKLRTIFNEIGREQLRIQIKDLLKEINRAEFI
>NZ_CP013844.1|WP_061332053.1|25549_26491_+|Rha-family-transcriptional-regulator
MKNKEFLEKLNMKEMISTQINSWELMLKKKGLKDKTIERKLNNLIYFYMHLTALRKDKERIKIDNISNIAFEYVRDGYFSEDNIDNEGCYGYRRNIYCNLREGFNFIYQGYFKNKIEVINDLIEEQKEVLEDVSKNKWFNVVGIKDDRETIQTKIIEELGLKVYFDKENNPYVLSHETAELIGKKHKDVTKAIRLILDRFTRAKKIALVENVDISMIEDHYTYNTNNGGTKDVITYRLSKDLVINYILGMSGDKYFDFKIKYQSAFNYIEREYKKLLEEHSTLKDSFLKMYNNIRKRNRDLLIKEHNKKAKSK
>NZ_CP013844.1|WP_024931664.1|25212_25407_+|hypothetical-protein
MNKTLKLKQFNNKIYLYNRKNPVTVGKEIKIIFHDAIVFSGQVTKENISEIQKMITYSDNYIIN
>NZ_CP013844.1|WP_154695167.1|36705_36882_-|hypothetical-protein
MIERIQCQQILLNYFKLFCDTQHIVLDLLEMYICCGQDTIKEGFYIKLFEVKTLYVIL
>NZ_CP013844.1|WP_051498540.1|36972_37560_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MLNNKIFMKRRGDIVYVDLGNPKGTNQGGKRPCIIVPNNKCTEHSTSIQIIPITSKLNKKRLPTHIFIKKDELNGLNEDSLILVEQTDLISTSQILSVVGRASDEIMRKVNAKLKIQFDLDKPDVNRIKAKIKTLKEMESYILKHNENSEELLNILKFQVSDFRDYCQEYNLNCSQYYVSKFNIINRYFQRNIAA
>NZ_CP013844.1|WP_024931653.1|37585_38086_+|tetratricopeptide-repeat-protein
MVYTLLKMKIREMYLEKKYEECNKKLTDLYRELIRDNQITLAEQNQLIWYYYFYKSNIFKNQNNLKDSLSFCLKSFRYITFKDKFNTEYKGTLFLLANIYKELNKKQKAIKTYEYLLRITKDKQYEMIFENINNLRQNSNVITFTNKQNKKYDSNKENNFKFCCYF
>NZ_CP013844.1|WP_024932249.1|38132_38585_+|hypothetical-protein
MKNKIRFIHDNQIKTGYIKTNLNKFKKEFILVEKGKNRYRIPIENLITTENELEINKKLLKHQIDNYISKYNLTIQWVNDTLKVSSILDEWFIEPSKNNLLILQHINKKNKDAKGKFHKQGIFYNYFSALRHIAEHDKTKLGIDFSNKSA
>NZ_CP013844.1|WP_061328811.1|38714_40184_+|hypothetical-protein
MIENKDYNYDRLIREITGCLSLKQFLMKKPFVIKELENKVNEERINNLFNQDIQIDMLDTRELYLITETFYKMLLDEEFISKLNEFQQQLQKDLNPELYFTEDEIRQYKNSVLPVEEEQDFKTVVFKNVKFMKEGIYSTVDDFNYILDLREKGILFYNINCQRETEKYEWRGTYVEKAKVFSKSIKEISESMYQDKYIPTYIAINVPSNGEEDFHVIDKENGLYDIIIKINKNTSLNLIDGNHRTTGGSLARNMCRRKGKEFLLNMGIQIMNLDPSSARQYIFQESKKNPLDETLTKAMEKTIENEIADYMNKGESPLAGKLGRELKDVKTLNKLTPLYVFAEGLKHFELDELDLIRKNKVKRFLKDFFNCILSFHKDKRRDRELSIEDMLKNKKLKEKKSEEEGYELNMNMFRGYLYIAAKLFNDPNWIEKIDTILKKIDYKKGGALEDMHLFKNEMSKTNIKKLEEYLENILSEVEESGENENVRKN
>NZ_CP013844.1|WP_024932251.1|40167_41229_+|hypothetical-protein
MSEKIRDFTSLNKLYFRELDERKKEYINFLKNEQDLQDITVDNYTNQIYKIRAFEEIIDRDRTIEYFTLDEISKLLENMTFSSESSAIAYKNRILDYLKFCTEHYGIQKDIGLLNTISQKEFIQGLVNKRLKYLKYVTEGTLYEAVQDLVNPQDRLMALLIYEGVKGTNHADLINIKKEQYDKENKILEYIEQDTGKTKQLRCNEFLSDEIEKTILSDTYYFKNGKGTGRHDMSDIVNSPYLVAPTAQLNARMNNYSGQQVYGQTIQSRILKIFKHFLDINGQHITVQSLYHSGIVNRMVKLTEEKYAGQKLKKVDFVKYIEQNEKLKLQAGYRLYDIYENLYNLFKNDIISF
>NZ_CP013844.1|WP_024932252.1|41616_41898_+|hypothetical-protein
MEVKLMNYLKGNKGYGITISEIGGDEKFLEDMCYKHNTNLKRIEILGKNEFLEMDKYIIKMENIVNIEEDISNISIFTESETENKEIIIENWD
>NZ_CP013844.1|WP_024932253.1|42042_43329_+|hypothetical-protein
MKNNLKECLEILKSIGNDSSRIAKETILKENKDNQLLKDILFFLYNPYIVTGISTKKLNKKVKLEVDNKLNTIIDVMDFLKTNNTGTDEHIKVIQNWINNQDLQYQDILKQLVTKSLKIGITSKTINKIHKNFIPEFNVMLAEKYHENINRVKGKFIITTKLDGNRMVLVKENGAIKTFSRQGQLIEGLIDIIEDAKQLQDNMVYDGEILLKNDKNLDSKQLFQETQKIIRKKDIKKTNLIFNIFDMMPLDEFKQGVSINDTLTRKNQLHDILESLETNWVKEVPMLYVGEDINKIDELLNIAVQNGEEGIMINLVDSKYQCKRTKDLLKVKIMNSSDCKIIGYEEGTGRNEGVLGAFIIDYKGHNVKVGSGYTDEDRKMFWENKDAFIEKIIEVQYFEETKNQNGGISLRFPVYKCIRNDKIEPSYF
>NZ_CP013844.1|WP_061328812.1|43708_44893_+|replication-initiator-protein-A
MDKKEEEQEVETISLKSNQSINESNLMVIPFISMKKTKVKVLERYWISNGVRRGIKVVGSGEHGCPTIAELDVLLALFRILIKNVGFKYEYNRTTGKVSLPKTIHFTYQELSKELGYKTYGGALKKKLENSVKCLNEATIYSDLGLRDVEAGDYIYDFEGEDSFRILEDYKSFSYTKRKKKGEKIGDAKQVKSMQSVTISDFFFKNICNNYFKIYNYNQYLMLTKGVAKKLYLLLNQWSRGYEKYLTYIKLYDMLSLDVAKNENNEEIDKKKAYYYNRIIKDALDELTTVKFIQDYDIRTNDGINLIFNINKRNKNRFLDKYNDEKEIINRLQEIGLTLKEWTKYYRLDNQEYVKALLRYVDYKIENKNDIRDVLKFTIDGLKSENYDVKEFIG
>NZ_CP013844.1|WP_024932310.1|45200_45554_+|hypothetical-protein
MDIINGIEIYSISKEAYKTYKEQAKQGRNASSEIIRRKLTALVINAVERKRIFKNKFTCRFGGFVMVVNEDTKMIEVLFWDNFKTHKSTAPRKSVDNLLETYKKLGLSKSGDELLVA

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Crispr_ID: NZ_CP013844_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013844_3

36572-36737

TypeI-B

Consensus_repeat	Method
ATTATCACATAACATATAATGTTTTTAAATTAT	CRISPRCasFinder

2 spacers

cas3,cas5,cas7b,cas8b1

The CRISPR arrays of NZ_CP013844_3

>merge|NZ_CP013844|3|36572-36737|CRISPRCasFinder
GTTATAAGACAACATCGTATGTTTTTAAATTATGTATAAAATAGTTGATTTGATAGTTTACTAAAAGTTATAATATAACATCATATGTTTTTAAATTAATGTAGCATATAAAATATTTCTTATCAAATAGCAAGTTATAATATAACATATAATGTTTTAACTTCAA

>NZ_CP013844|3|4|36572-36737|CRISPRCasFinder
GTTATAAGACAACATCGTATGTTTTTAAATTAT	GTATAAAATAGTTGATTTGATAGTTTACTAAAA
GTTATAATATAACATCATATGTTTTTAAATTAA	TGTAGCATATAAAATATTTCTTATCAAATAGCAA
GTTATAATATAACATATAATGTTTTAACTTCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013844.1\|WP_024931653.1\|37585_38086_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|372510
NZ_CP013844.1\|WP_051498540.1\|36972_37560_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP013844.1\|WP_024932310.1\|45200_45554_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932251.1\|40167_41229_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061328810.1\|28293_28530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932253.1\|42042_43329_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222893
NZ_CP013844.1\|WP_024931656.1\|32186_32936_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_CP013844.1\|WP_024931655.1\|33770_36236_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP013844.1\|WP_024931662.1\|26663_27455_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931661.1\|27658_28111_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931657.1\|31255_32185_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_CP013844.1\|WP_061328811.1\|38714_40184_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024932249.1\|38132_38585_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931658.1\|29480_31253_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NZ_CP013844.1\|WP_024932252.1\|41616_41898_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061332053.1\|25549_26491_+\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378235
NZ_CP013844.1\|WP_024931664.1\|25212_25407_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_024931659.1\|28720_29467_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273848
NZ_CP013844.1\|WP_154695545.1\|45595_45739_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013844.1\|WP_061328812.1\|43708_44893_+\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|370826

Protein	Function_ID	Function_description	E-value
NZ_CP013844.1\|WP_051498540.1\|36972_37560_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.85927e-26
NZ_CP013844.1\|WP_024931653.1\|37585_38086_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|372510	pfam13176, TPR_7, Tetratricopeptide repeat.	0.00142647
NZ_CP013844.1\|WP_024931657.1\|31255_32185_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.65004e-17
NZ_CP013844.1\|WP_061328812.1\|43708_44893_+\|replication-initiator-protein-A	gnl\|CDD\|370826	pfam10134, RPA, Replication initiator protein A. Members of this family of bacterial proteins are single-stranded DNA binding proteins that are involved in DNA replication, repair and recombination.	9.56918e-06
NZ_CP013844.1\|WP_024931656.1\|32186_32936_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	8.29076e-27
NZ_CP013844.1\|WP_024931655.1\|33770_36236_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	6.31332e-26
NZ_CP013844.1\|WP_061332053.1\|25549_26491_+\|Rha-family-transcriptional-regulator	gnl\|CDD\|378235	pfam09669, Phage_pRha, Phage regulatory protein Rha (Phage_pRha). Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.	3.67602e-07
NZ_CP013844.1\|WP_024931659.1\|28720_29467_+\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.46554e-07
NZ_CP013844.1\|WP_024932253.1\|42042_43329_+\|hypothetical-protein	gnl\|CDD\|222893	PHA02587, 30, DNA ligase; Provisional.	1.84323e-49

>NZ_CP013844.1|WP_024931655.1|33770_36236_+|CRISPR-associated-helicase/endonuclease-Cas3
MDKYLSRPNEDLIIHLNLTINNYNNYCKTNNLDKIIKNIISKLLQENNIKNEEASKQVYEMFINSIWLHDIGKINPYFQAYISNPNFKDYEFNNENKKHSILSSLIYLNIYYGKIKDVIYSKNRRENKNIKILLYDLLISFAYCISKHHTSLKDFDSIIFFNKLDNTVIQNNLLINNLNIDKEFIKKLKQINYKDVVYTNEFTKYILIKLCYSSIVTCDFLAVYNFYNKKQFHTNAINKNKLKQFNDKYNNLDIIKSIRNYPYNKDKLGKLNKMRTEMFLESESNLMKCISDNIFYLEAPTGSGKSNTSLNLALNILNNSKQFNKIISVNPYNAISEQTYNNTRNSLLIDDKDVVLINSQTEIIESDIEDETHYSKDFLDNQLLNYPVSIISHVKLFKALFSNNRIDNLMLFNIINSVIIIDEVQSYKNNLWIHIINSFKQFSDLLNFKIIIMSATLPKMDCLLEDKTYISNLIHNKNYYYNYFKNRVSLNFNLLNIKQFNKNILCDKINIEIKNNKRILVEFIKNKTANEIYNYYKQKFKSADYLVFNITSNCNSLYKQNVLKLINEKDDKNNFVNQKILVICTQTIEAGVDIDMDVGFKDISLLDSDEQFCGRINRNFKREGVVYFFHLDKITDVYKDDYRCERNLLNEQWQHLLITKQFNKFYELNYKRLLEEEKLNKDYYTYKNNLRTIQFEEIDKTMTLIDEQNCNLYLYCKLKLKDITIDSKNMFNKYIELKKDCNMDYSKKMIKLSKLKKWLGLFTYKFKVFNKNKPSIYNDYIDNYYILENPNEYIDIKEGFINEFSLFNMNKYIEDCNGLFL
>NZ_CP013844.1|WP_024931656.1|32186_32936_+|type-I-B-CRISPR-associated-protein-Cas5
MECLKFDLGGKTAFFKKPEINDVNFTFSNIHKIATLGMIGAIIGLNGRQQSKENGKIKFYETLKSIELSIVPFSPYFSKTYTIFNNATGFANKSASKHGATQNIKQQWLTNPKWTIYLKQGALDNTIWGKIKKYFLQGNYVYEPYLGGRPHIANITNVNLIDIDNIKNKEDIYKVDSLVKYNEIIDIDSQVYENCEDEYSYCLKEYTPIKLDDRGLYITEKMLHTNYEIYEVKNTNNFYKYNNNILYFI
>NZ_CP013844.1|WP_024931657.1|31255_32185_+|type-I-CRISPR-associated-protein-Cas7
MKMNNRVYGVTGIGVRNNNFNAGFDKTPKTLSNGTIFGAHQALKYPNRVFWDKLGEKVFYLKSYTEDGNVKKINERFQELFQMEDKDIQAVKSNLFKCVDVMNHGAAYTGNVSVDIRGAVQINNGDNKYELTTIDIFNILSPFGNKNSEKDTKQSSLGDTVVTDEAHYVYSINVNPFEYDKYIGTIEGFEGYTREAYDLFKEASLIAVSDYNSASKTGCQNEFTIFVELKDEMQGKFNLNELGQYIKVYNSENSNKRIYDLTILTEILNSGNISKDIKSIEIYYNPYTLELLENIENAKRFNIITREEI
>NZ_CP013844.1|WP_024931658.1|29480_31253_+|hypothetical-protein
MFKELIDEIGYNNILEYCENANLQNGIYIKINKDGNIEDKNIIEIENDKKDIENIELINWFKQRNCYSNYIDSNKAIVQRGKGVKTPKIVTSCNCYSVFFNVATILKNSKKMEMSLDKYCKNMITEYFDALINNIMNDKNGLSSIFKSNNIKSYMKKNKTTITKMIKKFFMNEYLLAQDKHRKKCINETKEILIQNIFVLINKLSNVKNIDKKKIKIFIDSEVDDYKKEYLLYLKPRIFLNNENNLILDDKIYGLSSELFTINSKKPLLKTNANLTDIPCLISIKGAIKYRNLIVYLKGNLSKTRELGYDLIFDKDGINVFDIIPFNKKDKLELKPLIIKDYLNKSFDTVEINNKKSLENSFNYFLDGNLYSNKINDNSKAKSFVVMYRDIISNYVYKDIDRDFLYALPKILNQLLNANLNPKKNVFDIMKCFNFRLSLLEYFKNNEKGEVIMKLNNDLKERLRDINTFTINSREEFIYICGQLGYYLNSRSKASPENKKMMLVNTYINCNNIELLKRKLQQDISKYSYDIQLNNDRFKKIIEQISLFKFDNNSISSSEKDYLLAGLFGNNLVYYEKKNNNKNNNNMEGK
>NZ_CP013844.1|WP_024931659.1|28720_29467_+|hypothetical-protein
MLNKNYELRIKIYLLRDIPLEDANEILSKAIDYTMLLNKNLRPIHTNKGFKHYSFSTPYPVESDRVYKKDRIYSFMIRDYSKQKIKDFQSVFSKLRLNEFVVLTTEIKEYHKKRISHIYTITPTVLTLLEEEVPDKLKTIKTKQKCWVKGCNHLLLIDRIENNLIKKYKDLTQKDIVVNNDIIESVEITNKVPIKINYKDSAIIGNKFKITFAQNELTQEIANLSVVEGILEKNSSLGCGFVKPAFVE
>NZ_CP013844.1|WP_061328810.1|28293_28530_+|hypothetical-protein
MTNSLKNTIDTDKNREAVNRAKKAIKQYELELKSLDIQMTKNNIILDKYINSDEYKDNLKEIQELEDRERELDKESKK
>NZ_CP013844.1|WP_024931661.1|27658_28111_+|hypothetical-protein
MEKIKFIYIDVEEETKEIKQLLDKGLIKYFYGKDSNEPDFIFLSENEDIIKSSITSEYRISNILRQLIIMFDGSNINIRNLWGDEINLDYKTLLNLMKENLNSYLSEDTQELIYQAEIPADKLTNIINQNGKEQLQMQIEDLLMESKKVI
>NZ_CP013844.1|WP_024931662.1|26663_27455_+|hypothetical-protein
MEIKNIQQLIELKKLKWSNPYTQRDFEVNSIDEFKYLLENYLNKFAFGVTYNTFKYTIFKEDDYIYIRNNDTYKFKNGYTGNITEEYTLKENSIDNIIDFIISSPDKNDKRRTRIKFIYIDVDDITDEMKQLLDKGLMKYFYGKNSCEPEFIYLAENEHIIKNTLTAEYCILDFASKLSEIFDCTDMTVRNIWNDEISFYHGRIEDLISDNLYGYIPESKQKEIFNTENPSNKLRTIFNEIGREQLRIQIKDLLKEINRAEFI
>NZ_CP013844.1|WP_061332053.1|25549_26491_+|Rha-family-transcriptional-regulator
MKNKEFLEKLNMKEMISTQINSWELMLKKKGLKDKTIERKLNNLIYFYMHLTALRKDKERIKIDNISNIAFEYVRDGYFSEDNIDNEGCYGYRRNIYCNLREGFNFIYQGYFKNKIEVINDLIEEQKEVLEDVSKNKWFNVVGIKDDRETIQTKIIEELGLKVYFDKENNPYVLSHETAELIGKKHKDVTKAIRLILDRFTRAKKIALVENVDISMIEDHYTYNTNNGGTKDVITYRLSKDLVINYILGMSGDKYFDFKIKYQSAFNYIEREYKKLLEEHSTLKDSFLKMYNNIRKRNRDLLIKEHNKKAKSK
>NZ_CP013844.1|WP_024931664.1|25212_25407_+|hypothetical-protein
MNKTLKLKQFNNKIYLYNRKNPVTVGKEIKIIFHDAIVFSGQVTKENISEIQKMITYSDNYIIN
>NZ_CP013844.1|WP_051498540.1|36972_37560_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MLNNKIFMKRRGDIVYVDLGNPKGTNQGGKRPCIIVPNNKCTEHSTSIQIIPITSKLNKKRLPTHIFIKKDELNGLNEDSLILVEQTDLISTSQILSVVGRASDEIMRKVNAKLKIQFDLDKPDVNRIKAKIKTLKEMESYILKHNENSEELLNILKFQVSDFRDYCQEYNLNCSQYYVSKFNIINRYFQRNIAA
>NZ_CP013844.1|WP_024931653.1|37585_38086_+|tetratricopeptide-repeat-protein
MVYTLLKMKIREMYLEKKYEECNKKLTDLYRELIRDNQITLAEQNQLIWYYYFYKSNIFKNQNNLKDSLSFCLKSFRYITFKDKFNTEYKGTLFLLANIYKELNKKQKAIKTYEYLLRITKDKQYEMIFENINNLRQNSNVITFTNKQNKKYDSNKENNFKFCCYF
>NZ_CP013844.1|WP_024932249.1|38132_38585_+|hypothetical-protein
MKNKIRFIHDNQIKTGYIKTNLNKFKKEFILVEKGKNRYRIPIENLITTENELEINKKLLKHQIDNYISKYNLTIQWVNDTLKVSSILDEWFIEPSKNNLLILQHINKKNKDAKGKFHKQGIFYNYFSALRHIAEHDKTKLGIDFSNKSA
>NZ_CP013844.1|WP_061328811.1|38714_40184_+|hypothetical-protein
MIENKDYNYDRLIREITGCLSLKQFLMKKPFVIKELENKVNEERINNLFNQDIQIDMLDTRELYLITETFYKMLLDEEFISKLNEFQQQLQKDLNPELYFTEDEIRQYKNSVLPVEEEQDFKTVVFKNVKFMKEGIYSTVDDFNYILDLREKGILFYNINCQRETEKYEWRGTYVEKAKVFSKSIKEISESMYQDKYIPTYIAINVPSNGEEDFHVIDKENGLYDIIIKINKNTSLNLIDGNHRTTGGSLARNMCRRKGKEFLLNMGIQIMNLDPSSARQYIFQESKKNPLDETLTKAMEKTIENEIADYMNKGESPLAGKLGRELKDVKTLNKLTPLYVFAEGLKHFELDELDLIRKNKVKRFLKDFFNCILSFHKDKRRDRELSIEDMLKNKKLKEKKSEEEGYELNMNMFRGYLYIAAKLFNDPNWIEKIDTILKKIDYKKGGALEDMHLFKNEMSKTNIKKLEEYLENILSEVEESGENENVRKN
>NZ_CP013844.1|WP_024932251.1|40167_41229_+|hypothetical-protein
MSEKIRDFTSLNKLYFRELDERKKEYINFLKNEQDLQDITVDNYTNQIYKIRAFEEIIDRDRTIEYFTLDEISKLLENMTFSSESSAIAYKNRILDYLKFCTEHYGIQKDIGLLNTISQKEFIQGLVNKRLKYLKYVTEGTLYEAVQDLVNPQDRLMALLIYEGVKGTNHADLINIKKEQYDKENKILEYIEQDTGKTKQLRCNEFLSDEIEKTILSDTYYFKNGKGTGRHDMSDIVNSPYLVAPTAQLNARMNNYSGQQVYGQTIQSRILKIFKHFLDINGQHITVQSLYHSGIVNRMVKLTEEKYAGQKLKKVDFVKYIEQNEKLKLQAGYRLYDIYENLYNLFKNDIISF
>NZ_CP013844.1|WP_024932252.1|41616_41898_+|hypothetical-protein
MEVKLMNYLKGNKGYGITISEIGGDEKFLEDMCYKHNTNLKRIEILGKNEFLEMDKYIIKMENIVNIEEDISNISIFTESETENKEIIIENWD
>NZ_CP013844.1|WP_024932253.1|42042_43329_+|hypothetical-protein
MKNNLKECLEILKSIGNDSSRIAKETILKENKDNQLLKDILFFLYNPYIVTGISTKKLNKKVKLEVDNKLNTIIDVMDFLKTNNTGTDEHIKVIQNWINNQDLQYQDILKQLVTKSLKIGITSKTINKIHKNFIPEFNVMLAEKYHENINRVKGKFIITTKLDGNRMVLVKENGAIKTFSRQGQLIEGLIDIIEDAKQLQDNMVYDGEILLKNDKNLDSKQLFQETQKIIRKKDIKKTNLIFNIFDMMPLDEFKQGVSINDTLTRKNQLHDILESLETNWVKEVPMLYVGEDINKIDELLNIAVQNGEEGIMINLVDSKYQCKRTKDLLKVKIMNSSDCKIIGYEEGTGRNEGVLGAFIIDYKGHNVKVGSGYTDEDRKMFWENKDAFIEKIIEVQYFEETKNQNGGISLRFPVYKCIRNDKIEPSYF
>NZ_CP013844.1|WP_061328812.1|43708_44893_+|replication-initiator-protein-A
MDKKEEEQEVETISLKSNQSINESNLMVIPFISMKKTKVKVLERYWISNGVRRGIKVVGSGEHGCPTIAELDVLLALFRILIKNVGFKYEYNRTTGKVSLPKTIHFTYQELSKELGYKTYGGALKKKLENSVKCLNEATIYSDLGLRDVEAGDYIYDFEGEDSFRILEDYKSFSYTKRKKKGEKIGDAKQVKSMQSVTISDFFFKNICNNYFKIYNYNQYLMLTKGVAKKLYLLLNQWSRGYEKYLTYIKLYDMLSLDVAKNENNEEIDKKKAYYYNRIIKDALDELTTVKFIQDYDIRTNDGINLIFNINKRNKNRFLDKYNDEKEIINRLQEIGLTLKEWTKYYRLDNQEYVKALLRYVDYKIENKNDIRDVLKFTIDGLKSENYDVKEFIG
>NZ_CP013844.1|WP_024932310.1|45200_45554_+|hypothetical-protein
MDIINGIEIYSISKEAYKTYKEQAKQGRNASSEIIRRKLTALVINAVERKRIFKNKFTCRFGGFVMVVNEDTKMIEVLFWDNFKTHKSTAPRKSVDNLLETYKKLGLSKSGDELLVA
>NZ_CP013844.1|WP_154695545.1|45595_45739_+|hypothetical-protein
MRYDVSEREIELEVVISESLDLIEQGETEKLKKLLEKEHSKIERNYN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP013844_1	1.2\|33196\|36\|NZ_CP013844\|PILER-CR	33196-33231	36	NZ_CP013845.1	2737020-2737055	0	1.0

1. spacer 1.2|33196|36|NZ_CP013844|PILER-CR matches to position: 2737020-2737055, mismatch: 0, identity: 1.0

cgtctaattggatcaaaaactctattaactttttga	CRISPR spacer
cgtctaattggatcaaaaactctattaactttttga	Protospacer
************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP013844_1	1.1\|33130\|36\|NZ_CP013844\|PILER-CR	33130-33165	36	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202684-202719	0	1.0
NZ_CP013844_1	1.1\|33130\|36\|NZ_CP013844\|PILER-CR	33130-33165	36	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33130-33165	0	1.0
NZ_CP013844_1	1.2\|33196\|36\|NZ_CP013844\|PILER-CR	33196-33231	36	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202750-202785	0	1.0
NZ_CP013844_1	1.2\|33196\|36\|NZ_CP013844\|PILER-CR	33196-33231	36	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33196-33231	0	1.0
NZ_CP013844_1	1.3\|33262\|36\|NZ_CP013844\|PILER-CR	33262-33297	36	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202816-202851	0	1.0
NZ_CP013844_1	1.3\|33262\|36\|NZ_CP013844\|PILER-CR	33262-33297	36	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33262-33297	0	1.0
NZ_CP013844_1	1.4\|33130\|39\|NZ_CP013844\|CRISPRCasFinder,CRT	33130-33168	39	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202684-202722	0	1.0
NZ_CP013844_1	1.4\|33130\|39\|NZ_CP013844\|CRISPRCasFinder,CRT	33130-33168	39	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33130-33168	0	1.0
NZ_CP013844_1	1.5\|33196\|39\|NZ_CP013844\|CRISPRCasFinder,CRT	33196-33234	39	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202750-202788	0	1.0
NZ_CP013844_1	1.5\|33196\|39\|NZ_CP013844\|CRISPRCasFinder,CRT	33196-33234	39	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33196-33234	0	1.0
NZ_CP013844_1	1.6\|33262\|39\|NZ_CP013844\|CRISPRCasFinder,CRT	33262-33300	39	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202816-202854	0	1.0
NZ_CP013844_1	1.6\|33262\|39\|NZ_CP013844\|CRISPRCasFinder,CRT	33262-33300	39	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33262-33300	0	1.0
NZ_CP013844_1	1.7\|33328\|38\|NZ_CP013844\|CRISPRCasFinder,CRT	33328-33365	38	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202882-202919	0	1.0
NZ_CP013844_1	1.7\|33328\|38\|NZ_CP013844\|CRISPRCasFinder,CRT	33328-33365	38	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33328-33365	0	1.0
NZ_CP013844_1	1.8\|33393\|39\|NZ_CP013844\|CRT	33393-33431	39	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	202947-202985	0	1.0
NZ_CP013844_1	1.8\|33393\|39\|NZ_CP013844\|CRT	33393-33431	39	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33393-33431	0	1.0
NZ_CP013844_1	1.9\|33459\|39\|NZ_CP013844\|CRT	33459-33497	39	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	203013-203051	0	1.0
NZ_CP013844_1	1.9\|33459\|39\|NZ_CP013844\|CRT	33459-33497	39	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33459-33497	0	1.0
NZ_CP013844_1	1.10\|33525\|39\|NZ_CP013844\|CRT,CRISPRCasFinder	33525-33563	39	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	203079-203117	0	1.0
NZ_CP013844_1	1.10\|33525\|39\|NZ_CP013844\|CRT,CRISPRCasFinder	33525-33563	39	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33525-33563	0	1.0
NZ_CP013844_1	1.11\|33591\|37\|NZ_CP013844\|CRT	33591-33627	37	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	203145-203181	0	1.0
NZ_CP013844_1	1.11\|33591\|37\|NZ_CP013844\|CRT	33591-33627	37	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	33591-33627	0	1.0
NZ_CP013844_2	2.1\|36409\|32\|NZ_CP013844\|CRISPRCasFinder	36409-36440	32	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	245-276	0	1.0
NZ_CP013844_2	2.1\|36409\|32\|NZ_CP013844\|CRISPRCasFinder	36409-36440	32	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	36409-36440	0	1.0
NZ_CP013844_3	3.1\|36605\|33\|NZ_CP013844\|CRISPRCasFinder	36605-36637	33	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	441-473	0	1.0
NZ_CP013844_3	3.1\|36605\|33\|NZ_CP013844\|CRISPRCasFinder	36605-36637	33	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	36605-36637	0	1.0
NZ_CP013844_3	3.2\|36671\|34\|NZ_CP013844\|CRISPRCasFinder	36671-36704	34	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	507-540	0	1.0
NZ_CP013844_3	3.2\|36671\|34\|NZ_CP013844\|CRISPRCasFinder	36671-36704	34	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	36671-36704	0	1.0
NZ_CP013844_3	3.2\|36671\|34\|NZ_CP013844\|CRISPRCasFinder	36671-36704	34	MH920640	Synechoccus phage S-E7, complete genome	124090-124123	7	0.794
NZ_CP013844_3	3.2\|36671\|34\|NZ_CP013844\|CRISPRCasFinder	36671-36704	34	MH920639	Synechoccus phage S-P4, partial genome	134518-134551	7	0.794
NZ_CP013844_3	3.2\|36671\|34\|NZ_CP013844\|CRISPRCasFinder	36671-36704	34	HQ634189	Cyanophage Syn30 genomic sequence	66079-66112	7	0.794
NZ_CP013844_1	1.2\|33196\|36\|NZ_CP013844\|PILER-CR	33196-33231	36	AP014127	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C44-MedDCM-OCT-S31-C46, * SEQUENCING IN PROGRESS *	4729-4764	10	0.722
NZ_CP013844_3	3.2\|36671\|34\|NZ_CP013844\|CRISPRCasFinder	36671-36704	34	CP024685	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence	207820-207853	10	0.706
NZ_CP013844_3	3.2\|36671\|34\|NZ_CP013844\|CRISPRCasFinder	36671-36704	34	NZ_MF477836	Macrococcus canis strain KM0218 plasmid pKM0218, complete sequence	5973-6006	11	0.676

1. spacer 1.1|33130|36|NZ_CP013844|PILER-CR matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

aattactcaaggaaaaatactgctttagaaaacttc	CRISPR spacer
aattactcaaggaaaaatactgctttagaaaacttc	Protospacer
************************************

2. spacer 1.1|33130|36|NZ_CP013844|PILER-CR matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

aattactcaaggaaaaatactgctttagaaaacttc	CRISPR spacer
aattactcaaggaaaaatactgctttagaaaacttc	Protospacer
************************************

3. spacer 1.2|33196|36|NZ_CP013844|PILER-CR matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

cgtctaattggatcaaaaactctattaactttttga	CRISPR spacer
cgtctaattggatcaaaaactctattaactttttga	Protospacer
************************************

4. spacer 1.2|33196|36|NZ_CP013844|PILER-CR matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

cgtctaattggatcaaaaactctattaactttttga	CRISPR spacer
cgtctaattggatcaaaaactctattaactttttga	Protospacer
************************************

5. spacer 1.3|33262|36|NZ_CP013844|PILER-CR matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

taattatttgttgcaatctatatataataaatatga	CRISPR spacer
taattatttgttgcaatctatatataataaatatga	Protospacer
************************************

6. spacer 1.3|33262|36|NZ_CP013844|PILER-CR matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

taattatttgttgcaatctatatataataaatatga	CRISPR spacer
taattatttgttgcaatctatatataataaatatga	Protospacer
************************************

7. spacer 1.4|33130|39|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

aattactcaaggaaaaatactgctttagaaaacttcgtc	CRISPR spacer
aattactcaaggaaaaatactgctttagaaaacttcgtc	Protospacer
***************************************

8. spacer 1.4|33130|39|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

aattactcaaggaaaaatactgctttagaaaacttcgtc	CRISPR spacer
aattactcaaggaaaaatactgctttagaaaacttcgtc	Protospacer
***************************************

9. spacer 1.5|33196|39|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

cgtctaattggatcaaaaactctattaactttttgagtt	CRISPR spacer
cgtctaattggatcaaaaactctattaactttttgagtt	Protospacer
***************************************

10. spacer 1.5|33196|39|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

cgtctaattggatcaaaaactctattaactttttgagtt	CRISPR spacer
cgtctaattggatcaaaaactctattaactttttgagtt	Protospacer
***************************************

11. spacer 1.6|33262|39|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

taattatttgttgcaatctatatataataaatatgagtt	CRISPR spacer
taattatttgttgcaatctatatataataaatatgagtt	Protospacer
***************************************

12. spacer 1.6|33262|39|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

taattatttgttgcaatctatatataataaatatgagtt	CRISPR spacer
taattatttgttgcaatctatatataataaatatgagtt	Protospacer
***************************************

13. spacer 1.7|33328|38|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

atgaatgacaatcgctatacatgtagaacaatagagtt	CRISPR spacer
atgaatgacaatcgctatacatgtagaacaatagagtt	Protospacer
**************************************

14. spacer 1.7|33328|38|NZ_CP013844|CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

atgaatgacaatcgctatacatgtagaacaatagagtt	CRISPR spacer
atgaatgacaatcgctatacatgtagaacaatagagtt	Protospacer
**************************************

15. spacer 1.8|33393|39|NZ_CP013844|CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

tcgtatagtttttctgttaaaggaatttttcttttgtta	CRISPR spacer
tcgtatagtttttctgttaaaggaatttttcttttgtta	Protospacer
***************************************

16. spacer 1.8|33393|39|NZ_CP013844|CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

tcgtatagtttttctgttaaaggaatttttcttttgtta	CRISPR spacer
tcgtatagtttttctgttaaaggaatttttcttttgtta	Protospacer
***************************************

17. spacer 1.9|33459|39|NZ_CP013844|CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

tacgatgctgacgcctctgaaattgaaatagttacagtt	CRISPR spacer
tacgatgctgacgcctctgaaattgaaatagttacagtt	Protospacer
***************************************

18. spacer 1.9|33459|39|NZ_CP013844|CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

tacgatgctgacgcctctgaaattgaaatagttacagtt	CRISPR spacer
tacgatgctgacgcctctgaaattgaaatagttacagtt	Protospacer
***************************************

19. spacer 1.10|33525|39|NZ_CP013844|CRT,CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

tagaatatggaataagacattctttaaagatgatgagtt	CRISPR spacer
tagaatatggaataagacattctttaaagatgatgagtt	Protospacer
***************************************

20. spacer 1.10|33525|39|NZ_CP013844|CRT,CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

tagaatatggaataagacattctttaaagatgatgagtt	CRISPR spacer
tagaatatggaataagacattctttaaagatgatgagtt	Protospacer
***************************************

21. spacer 1.11|33591|37|NZ_CP013844|CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

tttaatagaataataagttttcaagcctttaagagtt	CRISPR spacer
tttaatagaataataagttttcaagcctttaagagtt	Protospacer
*************************************

22. spacer 1.11|33591|37|NZ_CP013844|CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

tttaatagaataataagttttcaagcctttaagagtt	CRISPR spacer
tttaatagaataataagttttcaagcctttaagagtt	Protospacer
*************************************

23. spacer 2.1|36409|32|NZ_CP013844|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

aaagcaatagcactttcaatgtctttttgctt	CRISPR spacer
aaagcaatagcactttcaatgtctttttgctt	Protospacer
********************************

24. spacer 2.1|36409|32|NZ_CP013844|CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

aaagcaatagcactttcaatgtctttttgctt	CRISPR spacer
aaagcaatagcactttcaatgtctttttgctt	Protospacer
********************************

25. spacer 3.1|36605|33|NZ_CP013844|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

gtataaaatagttgatttgatagtttactaaaa	CRISPR spacer
gtataaaatagttgatttgatagtttactaaaa	Protospacer
*********************************

26. spacer 3.1|36605|33|NZ_CP013844|CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

gtataaaatagttgatttgatagtttactaaaa	CRISPR spacer
gtataaaatagttgatttgatagtttactaaaa	Protospacer
*********************************

27. spacer 3.2|36671|34|NZ_CP013844|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 0, identity: 1.0

tgtagcatataaaatatttcttatcaaatagcaa	CRISPR spacer
tgtagcatataaaatatttcttatcaaatagcaa	Protospacer
**********************************

28. spacer 3.2|36671|34|NZ_CP013844|CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 0, identity: 1.0

tgtagcatataaaatatttcttatcaaatagcaa	CRISPR spacer
tgtagcatataaaatatttcttatcaaatagcaa	Protospacer
**********************************

29. spacer 3.2|36671|34|NZ_CP013844|CRISPRCasFinder matches to MH920640 (Synechoccus phage S-E7, complete genome) position: , mismatch: 7, identity: 0.794

tgtagcatataaaatatttcttatcaaatagcaa	CRISPR spacer
tcaaaccaataaaatttttcttatcaaatggcaa	Protospacer
*  *.*  ******* *************.****

30. spacer 3.2|36671|34|NZ_CP013844|CRISPRCasFinder matches to MH920639 (Synechoccus phage S-P4, partial genome) position: , mismatch: 7, identity: 0.794

tgtagcatataaaatatttcttatcaaatagcaa	CRISPR spacer
tcaaaccaataaaatttttcttatcaaatggcaa	Protospacer
*  *.*  ******* *************.****

31. spacer 3.2|36671|34|NZ_CP013844|CRISPRCasFinder matches to HQ634189 (Cyanophage Syn30 genomic sequence) position: , mismatch: 7, identity: 0.794

tgtagcatataaaatatttcttatcaaatagcaa	CRISPR spacer
tcaaaccaataaaatttttcttatcaaatggcaa	Protospacer
*  *.*  ******* *************.****

32. spacer 1.2|33196|36|NZ_CP013844|PILER-CR matches to AP014127 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C44-MedDCM-OCT-S31-C46, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 10, identity: 0.722

cgtctaattggatcaaaaactctattaactttttga	CRISPR spacer
tttaaatctgtatcaaaaaatctattaactttttct	Protospacer
. *  * .** ******** **************

33. spacer 3.2|36671|34|NZ_CP013844|CRISPRCasFinder matches to CP024685 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence) position: , mismatch: 10, identity: 0.706

tgtagcatataaaatatttcttatcaaatagcaa	CRISPR spacer
ttccttatataaaatacttcttatcagatatcgc	Protospacer
* .  .**********.*********.*** *.

34. spacer 3.2|36671|34|NZ_CP013844|CRISPRCasFinder matches to NZ_MF477836 (Macrococcus canis strain KM0218 plasmid pKM0218, complete sequence) position: , mismatch: 11, identity: 0.676

tgtagcatataaaatatttcttatcaaatagcaa	CRISPR spacer
aatcaaatttaaaatctttcttatcaaatatatt	Protospacer
 .* . ** ****** **************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

84844 : 95394

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061328829.1\|84844_86671_+	DHH family phosphoesterase	A0A1P8CX07	Bacillus_phage	2.9e-104	38.0
WP_024931748.1\|86716_88231_+	PHP domain-containing protein	A0A1P8CX14	Bacillus_phage	9.0e-120	46.4
WP_024931749.1\|88457_89273_+	GIY-YIG nuclease family protein	G3MA71	Bacillus_virus	1.9e-15	40.4
WP_024931999.1\|89482_92116_+	hypothetical protein	A0A1P8CX14	Bacillus_phage	2.1e-217	45.4
WP_024931998.1\|92121_94419_+	AAA family ATPase	A0A0K2FLP8	Brevibacillus_phage	1.5e-86	32.9
WP_024931997.1\|94519_94777_+	hypothetical protein	NA	NA	NA	NA
WP_061329097.1\|94827_95394_+	hypothetical protein	Q332D2	Clostridium_botulinum_C_phage	3.3e-43	48.9

DBSCAN-SWA_2

138351 : 174372

Bacillus_phage(33.33%)

transposase,tail,integrase

attL 136701:136715|attR 146416:146430

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
136701:136715	attL	NA	NA	NA	NA
WP_024932065.1\|138351_139311_-\|integrase	tyrosine-type recombinase/integrase	Q332C2	Clostridium_botulinum_C_phage	5.2e-105	60.8
WP_061329076.1\|139336_140926_-	hypothetical protein	Q332I6	Clostridium_botulinum_C_phage	4.1e-22	61.4
WP_024932068.1\|141003_141189_-	hypothetical protein	NA	NA	NA	NA
WP_061329075.1\|141502_142315_-\|integrase	tyrosine-type recombinase/integrase	S5M872	Bacillus_phage	4.7e-14	26.9
WP_024932070.1\|142715_143726_-	hypothetical protein	A0A0A7RU33	Clostridium_phage	1.8e-23	44.7
WP_024932071.1\|143791_144721_-	hypothetical protein	NA	NA	NA	NA
WP_024932072.1\|144723_145659_-	hypothetical protein	NA	NA	NA	NA
WP_024932073.1\|145812_147093_-	hypothetical protein	NA	NA	NA	NA
146416:146430	attR	NA	NA	NA	NA
WP_024932074.1\|147105_148122_-	hypothetical protein	NA	NA	NA	NA
WP_024932075.1\|148150_148456_-	hypothetical protein	NA	NA	NA	NA
WP_024932076.1\|148527_148950_-	hypothetical protein	NA	NA	NA	NA
WP_061329074.1\|148988_150584_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	3.9e-20	30.7
WP_061329073.1\|150604_150979_-	hypothetical protein	NA	NA	NA	NA
WP_154694974.1\|151253_151427_-	hypothetical protein	NA	NA	NA	NA
WP_024932472.1\|151428_151845_-	hypothetical protein	NA	NA	NA	NA
WP_061328754.1\|151878_155145_-	hypothetical protein	A0A0K2FMC4	Brevibacillus_phage	1.2e-12	32.1
WP_024932059.1\|155174_155408_-	hypothetical protein	NA	NA	NA	NA
WP_024932060.1\|155411_155660_-	hypothetical protein	NA	NA	NA	NA
WP_061328755.1\|155693_158393_-	hypothetical protein	A0A218KC90	Bacillus_phage	1.7e-68	28.8
WP_061329072.1\|158424_159051_-	hypothetical protein	NA	NA	NA	NA
WP_024932002.1\|159407_160520_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	3.6e-89	47.8
WP_075144826.1\|160629_160791_+	ribbon-helix-helix domain-containing protein	B5LPT4	Bacillus_virus	2.0e-06	66.7
WP_061329071.1\|161267_163502_-\|tail	phage tail family protein	A0A1P8CWP8	Bacillus_phage	2.5e-25	34.4
WP_024932519.1\|163552_164143_-	hypothetical protein	NA	NA	NA	NA
WP_024932518.1\|164362_165526_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	6.2e-76	43.0
WP_024932517.1\|165712_165913_+	helix-turn-helix domain-containing protein	A0A0C5ABM0	Bacteriophage	5.7e-14	55.4
WP_075144827.1\|166393_170839_-	C40 family peptidase	A0A0H3V0Q1	Geobacillus_virus	1.9e-37	32.7
WP_061329069.1\|171225_171852_-\|tail	phage tail tape measure protein	A0A1P8CWQ1	Bacillus_phage	2.3e-08	28.7
WP_024931615.1\|172162_173659_-	DUF1729 domain-containing protein	NA	NA	NA	NA
WP_024931614.1\|173823_174372_-	GNAT family N-acetyltransferase	Q8HA62	Vibrio_phage	3.5e-05	27.3

DBSCAN-SWA_3

184412 : 208128

Clostridium_botulinum_C_phage(58.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024931600.1\|184412_184931_-	hypothetical protein	Q331W6	Clostridium_botulinum_C_phage	1.0e-06	25.3
WP_024931599.1\|185033_186257_-	hypothetical protein	Q331W5	Clostridium_botulinum_C_phage	1.8e-41	29.2
WP_024931598.1\|186274_186685_-	hypothetical protein	Q331W4	Clostridium_botulinum_C_phage	2.3e-33	53.8
WP_024931597.1\|186705_187236_-	hypothetical protein	Q331W3	Clostridium_botulinum_C_phage	1.4e-59	61.8
WP_024931596.1\|187304_188360_-	hypothetical protein	Q331W2	Clostridium_botulinum_C_phage	9.4e-132	67.8
WP_061329067.1\|188388_188922_-	hypothetical protein	Q331W1	Clostridium_botulinum_C_phage	3.1e-59	63.5
WP_061329066.1\|188957_190403_-	hypothetical protein	Q331W0	Clostridium_botulinum_C_phage	9.3e-98	51.6
WP_164076814.1\|190435_190585_-	hypothetical protein	NA	NA	NA	NA
WP_024932198.1\|190603_192175_-	hypothetical protein	Q331V9	Clostridium_botulinum_C_phage	1.3e-182	62.0
WP_043013779.1\|192203_193016_-	hypothetical protein	V9VGI9	Lactococcus_phage	2.1e-14	27.9
WP_101514322.1\|193960_194983_-	hypothetical protein	NA	NA	NA	NA
WP_024932329.1\|195144_195783_-	hypothetical protein	NA	NA	NA	NA
WP_024932330.1\|195779_197054_-	hypothetical protein	A0A0H3V0M6	Geobacillus_virus	4.7e-61	37.0
WP_154695084.1\|197106_197262_-	hypothetical protein	NA	NA	NA	NA
WP_101514326.1\|197305_198028_-	antA/AntB antirepressor family protein	A0A0A7RUT3	Clostridium_phage	1.8e-17	40.6
WP_024932332.1\|198487_198793_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_024932333.1\|198818_199064_-	hypothetical protein	NA	NA	NA	NA
WP_024932334.1\|199125_199320_-	hypothetical protein	NA	NA	NA	NA
WP_024931723.1\|199371_200595_-	PhoH family protein	A0A0K2FL36	Brevibacillus_phage	1.5e-64	39.1
WP_024931722.1\|200695_200983_-	HU family DNA-binding protein	A4JWM7	Burkholderia_virus	9.0e-05	40.0
WP_061329065.1\|201079_201805_-	C40 family peptidase	A0A0A8WIF2	Clostridium_phage	8.4e-23	45.7
WP_101514323.1\|201889_202768_-	hypothetical protein	NA	NA	NA	NA
WP_024931719.1\|202951_203146_-	hypothetical protein	NA	NA	NA	NA
WP_024931718.1\|203502_204303_-	hypothetical protein	Q331U9	Clostridium_botulinum_C_phage	3.3e-52	44.6
WP_080443265.1\|204305_207134_-	hypothetical protein	Q331U7	Clostridium_botulinum_C_phage	4.8e-199	59.9
WP_024931717.1\|207174_208128_-	hypothetical protein	A0A1B0WLE1	Flavobacterium_phage	2.1e-05	38.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP013845

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

2. NZ_CP013844

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection