CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP025753	Escherichia coli strain CV839-06 chromosome, complete genome	10 crisprs	DinG,DEDDh,cas3,RT,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,c2c9_V-U4,WYL	22	10
NZ_CP025752	Escherichia coli strain CV839-06 plasmid pCV839-06-p2, complete sequence	0 crisprs	NA	0	1
NZ_CP025751	Escherichia coli strain CV839-06 plasmid pCV839-06-p1, complete sequence	0 crisprs	csa3	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP025753_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_1

145784-145875

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025753_1

>merge|NZ_CP025753|1|145784-145875|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP025753|1|1|145784-145875|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_001307708.1\|141317_142010_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP025753.1\|WP_001297178.1\|144341_145670_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP025753.1\|WP_000024560.1\|151152_151458_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP025753.1\|WP_001323677.1\|154692_155865_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992
NZ_CP025753.1\|WP_000209869.1\|151550_152150_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP025753.1\|WP_001120112.1\|155994_156687_+\|two-component-system-response-regulator-TorR	unknown	unknown	gnl\|CDD\|182711
NZ_CP025753.1\|WP_001384404.1\|142415_143216_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP025753.1\|WP_001044313.1\|147180_148422_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP025753.1\|WP_000420629.1\|150232_151153_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP025753.1\|WP_001126780.1\|142021_142408_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP025753.1\|WP_000191701.1\|139300_139939_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP025753.1\|WP_001352489.1\|140226_141318_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP025753.1\|WP_001018486.1\|133369_134878_-\|sodium/proline-symporter-PutP	unknown	unknown	gnl\|CDD\|185317
NZ_CP025753.1\|WP_001001171.1\|143225_143816_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP025753.1\|WP_001143120.1\|146915_147143_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP025753.1\|WP_001151437.1\|146298_146895_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP025753.1\|WP_000097602.1\|148713_149973_-\|YccE-family-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP025753.1\|WP_001028096.1\|143826_144321_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NZ_CP025753.1\|WP_001062101.1\|152146_154693_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP025753.1\|WP_001299828.1\|135298_139261_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_001307708.1\|141317_142010_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	5.84226e-169
NZ_CP025753.1\|WP_001297178.1\|144341_145670_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP025753.1\|WP_000024560.1\|151152_151458_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	5.75956e-65
NZ_CP025753.1\|WP_001323677.1\|154692_155865_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0
NZ_CP025753.1\|WP_000209869.1\|151550_152150_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	5.28244e-84
NZ_CP025753.1\|WP_001120112.1\|155994_156687_+\|two-component-system-response-regulator-TorR	gnl\|CDD\|182711	PRK10766, PRK10766, two-component system response regulator TorR.	5.89892e-138
NZ_CP025753.1\|WP_001384404.1\|142415_143216_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	8.05337e-142
NZ_CP025753.1\|WP_001044313.1\|147180_148422_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP025753.1\|WP_000420629.1\|150232_151153_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP025753.1\|WP_001126780.1\|142021_142408_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	5.99808e-85
NZ_CP025753.1\|WP_000191701.1\|139300_139939_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	1.3356e-153
NZ_CP025753.1\|WP_001352489.1\|140226_141318_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP025753.1\|WP_001018486.1\|133369_134878_-\|sodium/proline-symporter-PutP	gnl\|CDD\|185317	PRK15419, PRK15419, sodium/proline symporter PutP.	0
NZ_CP025753.1\|WP_001001171.1\|143225_143816_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	1.00331e-130
NZ_CP025753.1\|WP_001143120.1\|146915_147143_+\|hypothetical-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP025753.1\|WP_001151437.1\|146298_146895_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	8.51484e-133
NZ_CP025753.1\|WP_000097602.1\|148713_149973_-\|YccE-family-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP025753.1\|WP_001028096.1\|143826_144321_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	8.28716e-106
NZ_CP025753.1\|WP_001062101.1\|152146_154693_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP025753.1\|WP_001299828.1\|135298_139261_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0

>NZ_CP025753.1|WP_001297178.1|144341_145670_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNLLGLGKAVDFTLVSHAAWFGLPHFSTPAFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>NZ_CP025753.1|WP_001028096.1|143826_144321_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
>NZ_CP025753.1|WP_001001171.1|143225_143816_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
>NZ_CP025753.1|WP_001384404.1|142415_143216_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARVPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP025753.1|WP_001126780.1|142021_142408_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP025753.1|WP_001307708.1|141317_142010_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>NZ_CP025753.1|WP_001352489.1|140226_141318_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAVRMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP025753.1|WP_000191701.1|139300_139939_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
>NZ_CP025753.1|WP_001299828.1|135298_139261_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP025753.1|WP_001018486.1|133369_134878_-|sodium/proline-symporter-PutP
MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSYETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWLGLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQES
>NZ_CP025753.1|WP_001151437.1|146298_146895_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP025753.1|WP_001143120.1|146915_147143_+|hypothetical-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP025753.1|WP_001044313.1|147180_148422_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAATVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAQQGMVKSGECPPPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDANGFCPMDKFDSVLNEAVK
>NZ_CP025753.1|WP_000097602.1|148713_149973_-|YccE-family-protein
MSSNIHGISCTANNYLKQAWNNIKNEHEKNQKYSITLFENTLVCFMRLYKEIRRQKAEDYIPCLECDSLEKEFEEMQNDNDLSLFLRTLRTNDTETYSGVSEGITYTIQYVRDIDIVRVSLPGRGSESITDFKGYYWYGFMEYIENINACDDVFSEYCLDDENMSIQPEWINTPGISDLDTGIDLSGISFIQSEINKTYGLKYAPVDGDGYCLLRAILVLKEHEYSWALGSHKTQKQVYEEFIKIVDKQTIEALVDTAFNDLREDVKTLFGVNLQSDNKIQGQGGFLSWSFLSFKKEFIDSCLNDKKCILHLPEFIFNDNKARLVLDTDPEQKVNEVKNFLTALSDSICSLFIVNSNVASISLGNESFSTDDDLEYGYLINTGNHYDVYLPPELFAQAYELNNKERNAQIDFLTRYAIY
>NZ_CP025753.1|WP_000420629.1|150232_151153_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHSDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGHDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP025753.1|WP_000024560.1|151152_151458_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
>NZ_CP025753.1|WP_000209869.1|151550_152150_-|molecular-chaperone-TorD
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVVRCRQYDSFGFYAALSQLLLVLVESDHQNR
>NZ_CP025753.1|WP_001062101.1|152146_154693_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS
>NZ_CP025753.1|WP_001323677.1|154692_155865_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDMPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>NZ_CP025753.1|WP_001120112.1|155994_156687_+|two-component-system-response-regulator-TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC

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Crispr_ID: NZ_CP025753_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_2

408848-408992

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025753_2

>merge|NZ_CP025753|2|408848-408992|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>NZ_CP025753|2|2|408848-408992|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_001036475.1\|411459_412893_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP025753.1\|WP_001091569.1\|407498_408782_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP025753.1\|WP_000213425.1\|416348_417167_+\|pyridoxal-phosphatase	unknown	unknown	gnl\|CDD\|182523
NZ_CP025753.1\|WP_000951213.1\|404395_405436_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|185063
NZ_CP025753.1\|WP_000044868.1\|401832_402510_-\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
NZ_CP025753.1\|WP_000815449.1\|415198_416194_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NZ_CP025753.1\|WP_000891692.1\|417167_418226_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP025753.1\|WP_000118858.1\|403244_404399_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_CP025753.1\|WP_001295302.1\|398132_399041_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689
NZ_CP025753.1\|WP_001295301.1\|396746_397736_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP025753.1\|WP_000679972.1\|414204_415158_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP025753.1\|WP_000101993.1\|418917_419691_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NZ_CP025753.1\|WP_001356070.1\|405522_406812_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189
NZ_CP025753.1\|WP_000246761.1\|402502_403258_-\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340
NZ_CP025753.1\|WP_000604034.1\|418228_418918_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_CP025753.1\|WP_000593945.1\|409015_411277_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NZ_CP025753.1\|WP_000891515.1\|419857_420007_-\|multidrug-efflux-pump-accessory-protein-AcrZ	unknown	unknown	gnl\|CDD\|371231
NZ_CP025753.1\|WP_000042533.1\|399232_401254_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_CP025753.1\|WP_000767389.1\|406870_407347_+\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
NZ_CP025753.1\|WP_000723652.1\|412968_414021_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_001036475.1\|411459_412893_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NZ_CP025753.1\|WP_001091569.1\|407498_408782_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP025753.1\|WP_000213425.1\|416348_417167_+\|pyridoxal-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
NZ_CP025753.1\|WP_000951213.1\|404395_405436_-\|biotin-synthase-BioB	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
NZ_CP025753.1\|WP_000044868.1\|401832_402510_-\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	7.09172e-110
NZ_CP025753.1\|WP_000815449.1\|415198_416194_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NZ_CP025753.1\|WP_000891692.1\|417167_418226_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP025753.1\|WP_000118858.1\|403244_404399_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
NZ_CP025753.1\|WP_001295302.1\|398132_399041_+\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.22556e-139
NZ_CP025753.1\|WP_001295301.1\|396746_397736_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	0
NZ_CP025753.1\|WP_000679972.1\|414204_415158_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
NZ_CP025753.1\|WP_000101993.1\|418917_419691_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
NZ_CP025753.1\|WP_001356070.1\|405522_406812_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
NZ_CP025753.1\|WP_000246761.1\|402502_403258_-\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	7.9121e-172
NZ_CP025753.1\|WP_000604034.1\|418228_418918_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
NZ_CP025753.1\|WP_000593945.1\|409015_411277_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NZ_CP025753.1\|WP_000891515.1\|419857_420007_-\|multidrug-efflux-pump-accessory-protein-AcrZ	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
NZ_CP025753.1\|WP_000042533.1\|399232_401254_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP025753.1\|WP_000767389.1\|406870_407347_+\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	1.08182e-118
NZ_CP025753.1\|WP_000723652.1\|412968_414021_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0

>NZ_CP025753.1|WP_001091569.1|407498_408782_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NZ_CP025753.1|WP_000767389.1|406870_407347_+|kinase-inhibitor
MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTGYDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS
>NZ_CP025753.1|WP_001356070.1|405522_406812_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGKRLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAGGMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEYAEIAPDILCLGKALTGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAIIESGEWQQQVAAIEVQLREQLAPARDAEMVADVRVLGAIGVVETTRPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ
>NZ_CP025753.1|WP_000951213.1|404395_405436_-|biotin-synthase-BioB
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
>NZ_CP025753.1|WP_000118858.1|403244_404399_-|8-amino-7-oxononanoate-synthase
MSWQEKINAALDARRTADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>NZ_CP025753.1|WP_000246761.1|402502_403258_-|malonyl-ACP-O-methyltransferase-BioC
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERPHANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE
>NZ_CP025753.1|WP_000044868.1|401832_402510_-|ATP-dependent-dethiobiotin-synthetase-BioD
MSKRYFVTGTDTEVGKTVASCALLQAAKAVGYRTAGYKPVASGSEKTPEGLRNSDALALQHNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGKYINLALL
>NZ_CP025753.1|WP_000042533.1|399232_401254_-|excinuclease-ABC-subunit-B
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>NZ_CP025753.1|WP_001295302.1|398132_399041_+|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTPIQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQLLHNALEKALQALG
>NZ_CP025753.1|WP_001295301.1|396746_397736_-|GTP-3',8-cyclase-MoaA
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
>NZ_CP025753.1|WP_000593945.1|409015_411277_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYKIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NZ_CP025753.1|WP_001036475.1|411459_412893_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NZ_CP025753.1|WP_000723652.1|412968_414021_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NZ_CP025753.1|WP_000679972.1|414204_415158_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>NZ_CP025753.1|WP_000815449.1|415198_416194_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYSIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NZ_CP025753.1|WP_000213425.1|416348_417167_+|pyridoxal-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NZ_CP025753.1|WP_000891692.1|417167_418226_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMSKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>NZ_CP025753.1|WP_000604034.1|418228_418918_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NZ_CP025753.1|WP_000101993.1|418917_419691_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVAIFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>NZ_CP025753.1|WP_000891515.1|419857_420007_-|multidrug-efflux-pump-accessory-protein-AcrZ
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: NZ_CP025753_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_3

908923-909076

Orphan

Consensus_repeat	Method
CGCCTTATCCGGCCTACCGATCCAGCACAGGTTTGTAGGCATGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025753_3

>merge|NZ_CP025753|3|908923-909076|CRISPRCasFinder
CGCCTTATCCGGCCTACCGATCCAGCACAGGTTTGTAGGCATGATAAGACGCGTCAGCGTCGCATCAGGCATCTGCGCATAACCGCCGGATGCGGCGTAAACGCCTTATCCGGCCTACCGATCCGGCACAGGTTTGTAGGCATGATAAGACGCG

>NZ_CP025753|3|3|908923-909076|CRISPRCasFinder
CGCCTTATCCGGCCTACCGATCCAGCACAGGTTTGTAGGCATGATAAGACGCG	TCAGCGTCGCATCAGGCATCTGCGCATAACCGCCGGATGCGGCGTAAA
CGCCTTATCCGGCCTACCGATCCGGCACAGGTTTGTAGGCATGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_001323598.1\|907048_908788_+\|flagellar-type-III-secretion-system-protein-FlhA	unknown	unknown	gnl\|CDD\|224217
NZ_CP025753.1\|WP_000006256.1\|909105_909603_-\|REP-associated-tyrosine-transposase-RayT	unknown	unknown	gnl\|CDD\|224854
NZ_CP025753.1\|WP_001368474.1\|906318_907089_-\|putative-lateral-flagellar-export/assembly-protein-LafU	unknown	unknown	gnl\|CDD\|235860
NZ_CP025753.1\|WP_001118055.1\|916444_917215_+\|2-oxoglutaramate-amidase	unknown	unknown	gnl\|CDD\|182461
NZ_CP025753.1\|WP_001295202.1\|904170_904437_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181972
NZ_CP025753.1\|WP_000973093.1\|913330_915775_+\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236528
NZ_CP025753.1\|WP_000333380.1\|911539_912307_-\|class-II-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|372525
NZ_CP025753.1\|WP_000284050.1\|912512_913091_-\|D-sedoheptulose-7-phosphate-isomerase	unknown	unknown	gnl\|CDD\|179012
NZ_CP025753.1\|WP_001293003.1\|902356_903814_+\|cytosol-nonspecific-dipeptidase	unknown	unknown	gnl\|CDD\|184986
NZ_CP025753.1\|WP_001225679.1\|910828_911569_+\|murein-L,D-transpeptidase	unknown	unknown	gnl\|CDD\|225577
NZ_CP025753.1\|WP_000749881.1\|898748_899804_+\|phosphoporin-PhoE	unknown	unknown	gnl\|CDD\|182275
NZ_CP025753.1\|WP_001226155.1\|905192_906248_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP025753.1\|WP_042634233.1\|900301_901546_-\|esterase-FrsA	unknown	unknown	gnl\|CDD\|235337
NZ_CP025753.1\|WP_001291992.1\|901637_902096_-\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236395
NZ_CP025753.1\|WP_000532698.1\|915817_916291_-\|C-lysozyme-inhibitor	unknown	unknown	gnl\|CDD\|182187
NZ_CP025753.1\|WP_001059874.1\|904743_905196_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182099
NZ_CP025753.1\|WP_103042674.1\|919114_923368_-\|RHS-repeat-protein	unknown	unknown	gnl\|CDD\|225750
NZ_CP025753.1\|WP_000174677.1\|899842_900244_-\|sigma-factor-binding-protein-Crl	unknown	unknown	gnl\|CDD\|182882
NZ_CP025753.1\|WP_000009291.1\|909778_910537_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|223862
NZ_CP025753.1\|WP_000978828.1\|918653_919103_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_001323598.1\|907048_908788_+\|flagellar-type-III-secretion-system-protein-FlhA	gnl\|CDD\|224217	COG1298, FlhA, Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP025753.1\|WP_000006256.1\|909105_909603_-\|REP-associated-tyrosine-transposase-RayT	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.32036e-43
NZ_CP025753.1\|WP_001368474.1\|906318_907089_-\|putative-lateral-flagellar-export/assembly-protein-LafU	gnl\|CDD\|235860	PRK06778, PRK06778, hypothetical protein; Validated.	2.23907e-171
NZ_CP025753.1\|WP_001118055.1\|916444_917215_+\|2-oxoglutaramate-amidase	gnl\|CDD\|182461	PRK10438, PRK10438, C-N hydrolase family amidase; Provisional.	0
NZ_CP025753.1\|WP_001295202.1\|904170_904437_-\|hypothetical-protein	gnl\|CDD\|181972	PRK09588, PRK09588, hypothetical protein; Reviewed.	1.93527e-42
NZ_CP025753.1\|WP_000973093.1\|913330_915775_+\|acyl-CoA-dehydrogenase	gnl\|CDD\|236528	PRK09463, fadE, acyl-CoA dehydrogenase; Reviewed.	0
NZ_CP025753.1\|WP_000333380.1\|911539_912307_-\|class-II-glutamine-amidotransferase	gnl\|CDD\|372525	pfam13230, GATase_4, Glutamine amidotransferases class-II. This family captures members that are not found in pfam00310.	8.29603e-146
NZ_CP025753.1\|WP_000284050.1\|912512_913091_-\|D-sedoheptulose-7-phosphate-isomerase	gnl\|CDD\|179012	PRK00414, gmhA, D-sedoheptulose 7-phosphate isomerase.	1.61173e-142
NZ_CP025753.1\|WP_001293003.1\|902356_903814_+\|cytosol-nonspecific-dipeptidase	gnl\|CDD\|184986	PRK15026, PRK15026, aminoacyl-histidine dipeptidase; Provisional.	0
NZ_CP025753.1\|WP_001225679.1\|910828_911569_+\|murein-L,D-transpeptidase	gnl\|CDD\|225577	COG3034, COG3034, Uncharacterized protein conserved in bacteria [Function unknown].	1.07529e-116
NZ_CP025753.1\|WP_000749881.1\|898748_899804_+\|phosphoporin-PhoE	gnl\|CDD\|182275	PRK10159, PRK10159, phosphoporin PhoE.	0
NZ_CP025753.1\|WP_001226155.1\|905192_906248_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP025753.1\|WP_042634233.1\|900301_901546_-\|esterase-FrsA	gnl\|CDD\|235337	PRK05077, frsA, esterase FrsA.	0
NZ_CP025753.1\|WP_001291992.1\|901637_902096_-\|xanthine-phosphoribosyltransferase	gnl\|CDD\|236395	PRK09177, PRK09177, xanthine-guanine phosphoribosyltransferase; Validated.	5.05624e-113
NZ_CP025753.1\|WP_000532698.1\|915817_916291_-\|C-lysozyme-inhibitor	gnl\|CDD\|182187	PRK09993, PRK09993, C-lysozyme inhibitor; Provisional.	9.39999e-93
NZ_CP025753.1\|WP_001059874.1\|904743_905196_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182099	PRK09831, PRK09831, GNAT family N-acetyltransferase.	4.77997e-103
NZ_CP025753.1\|WP_103042674.1\|919114_923368_-\|RHS-repeat-protein	gnl\|CDD\|225750	COG3209, RhsA, Rhs family protein [Cell envelope biogenesis, outer membrane].	6.11164e-135
NZ_CP025753.1\|WP_000174677.1\|899842_900244_-\|sigma-factor-binding-protein-Crl	gnl\|CDD\|182882	PRK10984, PRK10984, sigma factor-binding protein Crl.	1.11584e-87
NZ_CP025753.1\|WP_000009291.1\|909778_910537_-\|C40-family-peptidase	gnl\|CDD\|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	3.3314e-41

>NZ_CP025753.1|WP_001323598.1|907048_908788_+|flagellar-type-III-secretion-system-protein-FlhA
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVCIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRISDNGDITHDVRHQLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKRPQAAEAEEKSLETLTRTITETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLSSMAPRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYNEVPDELELKIMGALM
>NZ_CP025753.1|WP_001368474.1|906318_907089_-|putative-lateral-flagellar-export/assembly-protein-LafU
MIVNSVSKSERESIIAALHGQSIFSGGGLSPLNKISPSHPPKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRMR
>NZ_CP025753.1|WP_001226155.1|905192_906248_-|DNA-polymerase-IV
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELHLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVILLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
>NZ_CP025753.1|WP_001059874.1|904743_905196_-|GNAT-family-N-acetyltransferase
MNNIQIRNYQPGDFQQLCAIFIRAVMMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFISRIERHIDMLFVDPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQIVKQQHVECRGAWFTNFYMRYKPQH
>NZ_CP025753.1|WP_001295202.1|904170_904437_-|hypothetical-protein
MEWYMGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVGMPDLHPGRGYPIGAAFFSVGRFYPARRRGNGAGNRNGPLL
>NZ_CP025753.1|WP_001293003.1|902356_903814_+|cytosol-nonspecific-dipeptidase
MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKGFHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDGEWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWLQADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGGEIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDALKSLVNTYQDILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRNSDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEAKGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIGPTITGPHSPDEQVHIKSVGHYWTLLTELLKEIPAK
>NZ_CP025753.1|WP_001291992.1|901637_902096_-|xanthine-phosphoribosyltransferase
MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDNYVVDIPQDTWIEQPWDMGVVFVPPISGR
>NZ_CP025753.1|WP_042634233.1|900301_901546_-|esterase-FrsA
MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLQGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDDALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITGWIEKRLC
>NZ_CP025753.1|WP_000174677.1|899842_900244_-|sigma-factor-binding-protein-Crl
MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADDFRDEPVKLTA
>NZ_CP025753.1|WP_000749881.1|898748_899804_+|phosphoporin-PhoE
MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYMSDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFGVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQFDFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNKLNINNDDIVAVGMTYQF
>NZ_CP025753.1|WP_000006256.1|909105_909603_-|REP-associated-tyrosine-transposase-RayT
MSEYRRYYIKGGTWFFTVNLRNRRSQLLTTQYQMLRHAIIKVKRDRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHAIRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAGDVTDINAGERIIL
>NZ_CP025753.1|WP_000009291.1|909778_910537_-|C40-family-peptidase
MSFMSSFLLGRFLHPGVFSLCVLLPLFASATTSHISFSYAARQRMQNRARLLKQYQTHLKKQASYIVEGNAESRRALRQHNREQIKQHPEWFPAPLKASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDQGFDCSGLVFYAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRTGENIRVSRLAEPFWQDHFLGARRILTEETIL
>NZ_CP025753.1|WP_001225679.1|910828_911569_+|murein-L,D-transpeptidase
MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPVYIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQLKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTGALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVNGRYVVSKPLSHEVVQPQLASNYTLPEAK
>NZ_CP025753.1|WP_000333380.1|911539_912307_-|class-II-glutamine-amidotransferase
MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGKGCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRNWTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIASLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTTPNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV
>NZ_CP025753.1|WP_000284050.1|912512_913091_-|D-sedoheptulose-7-phosphate-isomerase
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
>NZ_CP025753.1|WP_000973093.1|913330_915775_+|acyl-CoA-dehydrogenase
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLKEHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVPFQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLCSINVDDFDPEELATKPVKLPEKVRKVEAA
>NZ_CP025753.1|WP_000532698.1|915817_916291_-|C-lysozyme-inhibitor
MGRISSGGMMFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK
>NZ_CP025753.1|WP_001118055.1|916444_917215_+|2-oxoglutaramate-amidase
MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMFTSGFAMEAAASSLAQNDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTVHFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAIYVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIATADAHQATRIDAELSMVALREYREKFPAWQDADEFRLR
>NZ_CP025753.1|WP_000978828.1|918653_919103_-|hypothetical-protein
MMKYLMVLLSLFSGSVLGMGRVNELCGIDSVKTIEIINLPSYVTTLVPLSKEGLNEIYRYKVVVNEISDLYAGKIIDLLQMKYFRKEKYNNIRWGVSIISKGNNKCEIYFDAFGECGSVNGINVCFEKNEMIGWIKKEIPLLSQKIGGL
>NZ_CP025753.1|WP_103042674.1|919114_923368_-|RHS-repeat-protein
MGGKPAARQGDMTRKGLDIVQGSAGVLIGAPTGVACSVCPGGITYANPVNPLLGAKVLPGETDLALPGPLPFILSRAYSSYRTRTPAPVGVFGPGWKAPFDIRLQIRDEGLILNDSGGRSIHFEPLFPGEISYSRSESLWLARGGVAAQHSSQPLSALWQVLPEDVRLSPHVYLATNSLQGPWWILSWPERVPGADEVLPPEPPAYRVLTGVVDGFGRTLAFHRAAEGDVAGAVTGVTDGAGRRFHLVLTTQAQRAEVFRKQRATSLSSPAGPRSASSSLVFPDTLPAGTGYGTDNGIRLEAVWLTHDPAYPDEQPTAPLARYTYTAGGELRAVYDRSGTQVRGFTYDAEHAGRMVAHHYAGRPESCYRYDDTGRVTEQVNPEGLDYRFEYGESRVIITDSLNRREVLYTEGEGGLKRVVKKEHADGSITRSEYDEAGRLKAQTDAAGRRTEYSLHMASGAVTAVTGPDGRTVRYGYNSQRQVTSVTYPDGLRSSREYDEKGRLTAETSRSGETTRYSYDDPASELPTGIQDATGSTKQMAWSRYGQLLAFTDCSGYTTRYEYDRYGQQIAVHREEGISTYSSYNPRGQLVSQKDAQGREIRYEYSAAGDLTATISPDGKRSTIEYDKRGRPVSVTEGGLTRSMGYDAAGRITVLTNENGSQSTFRYDPVDRLTEQRGFDGRTQRYHYDLTGKLTQSEDEGLITLWHYDASDRITHRTVNGDPAEQWQYDEHGWLTTLSHTCEGHRVSVHYGYDDKGRLTGERQTVENPETGEMLWEHETGHAYSEQGLATRQEPDGLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETARSFGGAGSTAGYEQATAYSLTGQLQSRHLNLPQLDCDYTWNDNGQLVRISGPQECREYRYSGTGRLTGVHTTAANLDIDIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRYDEYGRLAEKTDRIPEGVIRMHDERTHHYHYDSQHRLVFYTRIQHGEPQVESRYLYDPLGRRTGKRVWRRERDLTGWMSLSRKPEETWYGWDGDRLTTVQTQQTRIQTVYQPGSFTPLLRIETENGEQAKARHRSLAEVLQEDTGVTLPAELAVMLGRLERELRQGSVSEESQQWLAQCGLTAEQMAAQLEAEYIPERKLHLYHCDHRGLPLALISPEGETAWQGEYDEWGNLLGEESAQHLQQSLRLPGQQYDEESGLYYNRNRYYDPLQGRYITQDPIGLRGEWNLYKYPLNPVRFIDSLGLKFHVNGDPSDFNQAVEYLKQDSQMKETIDFLSSSEETINIEYIEGTNVRFNSNNMAIYWNSRASLFCSTELNSKSQSPALGLGHEFAHAQYYLLDKENFMALLSRTDKKYENKEEARVITIIESRAAKTLGECTRGAHSGLPFYRVDGPLQTMKITGTPE

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Crispr_ID: NZ_CP025753_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_4

1118792-1118907

Orphan

Consensus_repeat	Method
AACGCCTGATGCGACGCTGACGCGTCTTATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025753_4

>merge|NZ_CP025753|4|1118792-1118907|CRISPRCasFinder
AACGCCTGATGCGACGCTGACGCGTCTTATCTGGCCTACGCGCTGTGTTTTTGTAGGCCGGATAAGCAAAGCGCATCCGGCATTCAACGCCTGATGCGACGCTGGCGCGTCTTATC

>NZ_CP025753|4|4|1118792-1118907|CRISPRCasFinder
AACGCCTGATGCGACGCTGACGCGTCTTATC	TGGCCTACGCGCTGTGTTTTTGTAGGCCGGATAAGCAAAGCGCATCCGGCATTC
AACGCCTGATGCGACGCTGGCGCGTCTTATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_000637846.1\|1106807_1107986_-\|sugar-efflux-transporter-SetA	unknown	unknown	gnl\|CDD\|129977
NZ_CP025753.1\|WP_000151734.1\|1117269_1118772_+\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP025753.1\|WP_001248770.1\|1108087_1108219_-\|glucose-uptake-inhibitor-SgrT	unknown	unknown	gnl\|CDD\|374203
NZ_CP025753.1\|WP_000951786.1\|1115558_1117259_+\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP025753.1\|WP_001295536.1\|1110126_1111110_+\|thiamine-ABC-transporter-substrate-binding-subunit	unknown	unknown	gnl\|CDD\|236883
NZ_CP025753.1\|WP_001200579.1\|1125951_1126767_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP025753.1\|WP_000916291.1\|1112679_1113378_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	unknown	unknown	gnl\|CDD\|182716
NZ_CP025753.1\|WP_001300811.1\|1114341_1115220_-\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP025753.1\|WP_001297366.1\|1108307_1109963_+\|HTH-type-transcriptional-regulator-SgrR	unknown	unknown	gnl\|CDD\|184188
NZ_CP025753.1\|WP_000525176.1\|1125175_1125835_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP025753.1\|WP_000610901.1\|1132524_1132902_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP025753.1\|WP_001117011.1\|1122257_1125164_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP025753.1\|WP_001065381.1\|1131700_1132522_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP025753.1\|WP_000888642.1\|1118971_1119667_+\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP025753.1\|WP_000241271.1\|1130714_1131704_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP025753.1\|WP_000800453.1\|1129428_1130715_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP025753.1\|WP_000035637.1\|1119741_1122093_+\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP025753.1\|WP_000235700.1\|1111085_1112696_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	unknown	unknown	gnl\|CDD\|181853
NZ_CP025753.1\|WP_001148419.1\|1113491_1114256_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP025753.1\|WP_000746150.1\|1127021_1129376_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_000637846.1\|1106807_1107986_-\|sugar-efflux-transporter-SetA	gnl\|CDD\|129977	TIGR00899, Sugar_efflux_transporter_A, sugar efflux transporter. This family of proteins is an efflux system for lactose, glucose, aromatic glucosides and galactosides, cellobiose, maltose, a-methyl glucoside and other sugar compounds. They are found in both gram-negative and gram-postitive bacteria. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP025753.1\|WP_000151734.1\|1117269_1118772_+\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP025753.1\|WP_001248770.1\|1108087_1108219_-\|glucose-uptake-inhibitor-SgrT	gnl\|CDD\|374203	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT.	0.00206924
NZ_CP025753.1\|WP_000951786.1\|1115558_1117259_+\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP025753.1\|WP_001295536.1\|1110126_1111110_+\|thiamine-ABC-transporter-substrate-binding-subunit	gnl\|CDD\|236883	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional.	0
NZ_CP025753.1\|WP_001200579.1\|1125951_1126767_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.49529e-169
NZ_CP025753.1\|WP_000916291.1\|1112679_1113378_+\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	gnl\|CDD\|182716	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ.	1.49788e-164
NZ_CP025753.1\|WP_001300811.1\|1114341_1115220_-\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP025753.1\|WP_001297366.1\|1108307_1109963_+\|HTH-type-transcriptional-regulator-SgrR	gnl\|CDD\|184188	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR.	0
NZ_CP025753.1\|WP_000525176.1\|1125175_1125835_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	1.37214e-159
NZ_CP025753.1\|WP_000610901.1\|1132524_1132902_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	3.63315e-76
NZ_CP025753.1\|WP_001117011.1\|1122257_1125164_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP025753.1\|WP_001065381.1\|1131700_1132522_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.76119e-148
NZ_CP025753.1\|WP_000888642.1\|1118971_1119667_+\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	1.31794e-177
NZ_CP025753.1\|WP_000241271.1\|1130714_1131704_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP025753.1\|WP_000800453.1\|1129428_1130715_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP025753.1\|WP_000035637.1\|1119741_1122093_+\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP025753.1\|WP_000235700.1\|1111085_1112696_+\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	gnl\|CDD\|181853	PRK09433, thiP, thiamine transporter membrane protein; Reviewed.	0
NZ_CP025753.1\|WP_001148419.1\|1113491_1114256_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.77639e-49
NZ_CP025753.1\|WP_000746150.1\|1127021_1129376_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0

>NZ_CP025753.1|WP_000151734.1|1117269_1118772_+|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
>NZ_CP025753.1|WP_000951786.1|1115558_1117259_+|ribulokinase
MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDTTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
>NZ_CP025753.1|WP_001300811.1|1114341_1115220_-|arabinose-operon-transcriptional-regulator-AraC
MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>NZ_CP025753.1|WP_001148419.1|1113491_1114256_-|DedA-family-protein
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGSVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGG
>NZ_CP025753.1|WP_000916291.1|1112679_1113378_+|thiamine-ABC-transporter-ATP-binding-protein-ThiQ
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTNELLSGKASASALLGITG
>NZ_CP025753.1|WP_000235700.1|1111085_1112696_+|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGNWVAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFTVIEKLPGRNVKTD
>NZ_CP025753.1|WP_001295536.1|1110126_1111110_+|thiamine-ABC-transporter-substrate-binding-subunit
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPKIKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
>NZ_CP025753.1|WP_001297366.1|1108307_1109963_+|HTH-type-transcriptional-regulator-SgrR
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
>NZ_CP025753.1|WP_001248770.1|1108087_1108219_-|glucose-uptake-inhibitor-SgrT
MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES
>NZ_CP025753.1|WP_000637846.1|1106807_1107986_-|sugar-efflux-transporter-SetA
MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREVGAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRHYLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPLAFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVRMLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVKRYGKRRMMVIAVAAGVLFYTGLIFFHSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMPGRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
>NZ_CP025753.1|WP_000888642.1|1118971_1119667_+|L-ribulose-5-phosphate-4-epimerase
MLEDLKRLVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIATGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP025753.1|WP_000035637.1|1119741_1122093_+|DNA-polymerase-II
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDIRNGAIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYIRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>NZ_CP025753.1|WP_001117011.1|1122257_1125164_+|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
>NZ_CP025753.1|WP_000525176.1|1125175_1125835_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
>NZ_CP025753.1|WP_001200579.1|1125951_1126767_-|co-chaperone-DjlA
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
>NZ_CP025753.1|WP_000746150.1|1127021_1129376_+|LPS-assembly-protein-LptD
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNSL
>NZ_CP025753.1|WP_000800453.1|1129428_1130715_+|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATADIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
>NZ_CP025753.1|WP_000241271.1|1130714_1131704_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRTYSPNSPAQPQTAGTLTLLPVALRESVTAGQLAVENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPLLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
>NZ_CP025753.1|WP_001065381.1|1131700_1132522_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
>NZ_CP025753.1|WP_000610901.1|1132524_1132902_+|Co2+/Mg2+-efflux-protein-ApaG
MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH

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Crispr_ID: NZ_CP025753_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_5

1141820-1141952

Orphan

Consensus_repeat	Method
ATCACCAATATTGAAAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP025753_5

>merge|NZ_CP025753|5|1141820-1141952|PILER-CR
ATCACCAATATTGAAAATGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTCCTCACCAATATTGAAAACATGGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGGATCACCAATATTGAAAG

>NZ_CP025753|5|1|1141820-1141952|PILER-CR
ATCACCAATATTGAAAA	TGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTC
CTCACCAATATTGAAAA	CATGGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGG
ATCACCAATATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_000597260.1\|1153333_1154482_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP025753.1\|WP_000543605.1\|1154937_1155759_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|223366
NZ_CP025753.1\|WP_001183198.1\|1136992_1138324_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP025753.1\|WP_001126376.1\|1150094_1153316_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_CP025753.1\|WP_000351348.1\|1146309_1147863_+\|crotonobetaine/carnitine-CoA-ligase	unknown	unknown	gnl\|CDD\|181195
NZ_CP025753.1\|WP_001287715.1\|1138665_1139952_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182273
NZ_CP025753.1\|WP_000004404.1\|1147971_1148757_+\|crotonobetainyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|179599
NZ_CP025753.1\|WP_000333120.1\|1149438_1149834_-\|carnitine-metabolism-transcriptional-regulator-CaiF	unknown	unknown	gnl\|CDD\|183154
NZ_CP025753.1\|WP_000600725.1\|1136354_1136885_-\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	unknown	unknown	gnl\|CDD\|234852
NZ_CP025753.1\|WP_000257192.1\|1132908_1133751_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP025753.1\|WP_000787103.1\|1142202_1143717_+\|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter	unknown	unknown	gnl\|CDD\|179568
NZ_CP025753.1\|WP_000203747.1\|1138381_1138669_-\|ferredoxin-like-protein-FixX	unknown	unknown	gnl\|CDD\|185346
NZ_CP025753.1\|WP_000610901.1\|1132524_1132902_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP025753.1\|WP_000349926.1\|1145018_1146236_+\|L-carnitine-CoA-transferase	unknown	unknown	gnl\|CDD\|179589
NZ_CP025753.1\|WP_000624375.1\|1133828_1134308_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP025753.1\|WP_000377129.1\|1134499_1136362_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	unknown	unknown	gnl\|CDD\|235131
NZ_CP025753.1\|WP_000122876.1\|1148762_1149353_+\|carnitine-operon-protein-CaiE	unknown	unknown	gnl\|CDD\|184189
NZ_CP025753.1\|WP_001091499.1\|1140002_1140944_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|235120
NZ_CP025753.1\|WP_000347117.1\|1143747_1144890_+\|crotonobetainyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|179566
NZ_CP025753.1\|WP_000692204.1\|1140958_1141729_-\|electron-transfer-flavoprotein-FixA	unknown	unknown	gnl\|CDD\|179569

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_000597260.1\|1153333_1154482_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP025753.1\|WP_000543605.1\|1154937_1155759_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|223366	COG0289, DapB, Dihydrodipicolinate reductase [Amino acid transport and metabolism].	1.09638e-141
NZ_CP025753.1\|WP_001183198.1\|1136992_1138324_-\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.4298e-59
NZ_CP025753.1\|WP_001126376.1\|1150094_1153316_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP025753.1\|WP_000351348.1\|1146309_1147863_+\|crotonobetaine/carnitine-CoA-ligase	gnl\|CDD\|181195	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated.	0
NZ_CP025753.1\|WP_001287715.1\|1138665_1139952_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182273	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional.	0
NZ_CP025753.1\|WP_000004404.1\|1147971_1148757_+\|crotonobetainyl-CoA-hydratase	gnl\|CDD\|179599	PRK03580, PRK03580, crotonobetainyl-CoA hydratase.	1.76707e-178
NZ_CP025753.1\|WP_000333120.1\|1149438_1149834_-\|carnitine-metabolism-transcriptional-regulator-CaiF	gnl\|CDD\|183154	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF.	2.96175e-74
NZ_CP025753.1\|WP_000600725.1\|1136354_1136885_-\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	gnl\|CDD\|234852	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF.	2.99389e-133
NZ_CP025753.1\|WP_000257192.1\|1132908_1133751_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP025753.1\|WP_000787103.1\|1142202_1143717_+\|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter	gnl\|CDD\|179568	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter.	0
NZ_CP025753.1\|WP_000203747.1\|1138381_1138669_-\|ferredoxin-like-protein-FixX	gnl\|CDD\|185346	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional.	2.23442e-69
NZ_CP025753.1\|WP_000610901.1\|1132524_1132902_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	3.63315e-76
NZ_CP025753.1\|WP_000349926.1\|1145018_1146236_+\|L-carnitine-CoA-transferase	gnl\|CDD\|179589	PRK03525, PRK03525, L-carnitine CoA-transferase.	0
NZ_CP025753.1\|WP_000624375.1\|1133828_1134308_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.07206e-127
NZ_CP025753.1\|WP_000377129.1\|1134499_1136362_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
NZ_CP025753.1\|WP_000122876.1\|1148762_1149353_+\|carnitine-operon-protein-CaiE	gnl\|CDD\|184189	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional.	2.12106e-142
NZ_CP025753.1\|WP_001091499.1\|1140002_1140944_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|235120	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein.	0
NZ_CP025753.1\|WP_000347117.1\|1143747_1144890_+\|crotonobetainyl-CoA-dehydrogenase	gnl\|CDD\|179566	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated.	0
NZ_CP025753.1\|WP_000692204.1\|1140958_1141729_-\|electron-transfer-flavoprotein-FixA	gnl\|CDD\|179569	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed.	6.8619e-170

>NZ_CP025753.1|WP_000692204.1|1140958_1141729_-|electron-transfer-flavoprotein-FixA
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
>NZ_CP025753.1|WP_001091499.1|1140002_1140944_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
>NZ_CP025753.1|WP_001287715.1|1138665_1139952_-|FAD-dependent-oxidoreductase
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILADGVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTDGLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYSAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSAMKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFTIDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL
>NZ_CP025753.1|WP_000203747.1|1138381_1138669_-|ferredoxin-like-protein-FixX
MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQVLELLVKACPAGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG
>NZ_CP025753.1|WP_001183198.1|1136992_1138324_-|MFS-transporter
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>NZ_CP025753.1|WP_000600725.1|1136354_1136885_-|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF
MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
>NZ_CP025753.1|WP_000377129.1|1134499_1136362_-|glutathione-regulated-potassium-efflux-system-protein-KefC
MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
>NZ_CP025753.1|WP_000624375.1|1133828_1134308_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
>NZ_CP025753.1|WP_000257192.1|1132908_1133751_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGEAAAS
>NZ_CP025753.1|WP_000610901.1|1132524_1132902_+|Co2+/Mg2+-efflux-protein-ApaG
MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
>NZ_CP025753.1|WP_000787103.1|1142202_1143717_+|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter
MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
>NZ_CP025753.1|WP_000347117.1|1143747_1144890_+|crotonobetainyl-CoA-dehydrogenase
MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
>NZ_CP025753.1|WP_000349926.1|1145018_1146236_+|L-carnitine-CoA-transferase
MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKARETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLSTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
>NZ_CP025753.1|WP_000351348.1|1146309_1147863_+|crotonobetaine/carnitine-CoA-ligase
MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLLTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
>NZ_CP025753.1|WP_000004404.1|1147971_1148757_+|crotonobetainyl-CoA-hydratase
MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGTEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEEAYRYIRSGVLKHYPSVLHSEDAVEGPLAFAEKRDPVWKGR
>NZ_CP025753.1|WP_000122876.1|1148762_1149353_+|carnitine-operon-protein-CaiE
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>NZ_CP025753.1|WP_000333120.1|1149438_1149834_-|carnitine-metabolism-transcriptional-regulator-CaiF
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVAEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
>NZ_CP025753.1|WP_001126376.1|1150094_1153316_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
>NZ_CP025753.1|WP_000597260.1|1153333_1154482_-|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK
>NZ_CP025753.1|WP_000543605.1|1154937_1155759_-|4-hydroxy-tetrahydrodipicolinate-reductase
MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNSL

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Crispr_ID: NZ_CP025753_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_6

2581042-2581181

Orphan

Consensus_repeat	Method
TTTGTATCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025753_6

>merge|NZ_CP025753|6|2581042-2581181|CRISPRCasFinder
TTTGTATCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCAACAGCAGTCGGATGCGGCGTAAACACCTTATCTGACCTACGTTTTGTGTCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA

>NZ_CP025753|6|5|2581042-2581181|CRISPRCasFinder
TTTGTATCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA	ACAGCAGTCGGATGCGGCGTAAACACCTTATCTGACCTACGT
TTTGTGTCGTTGTAGGCCTGATAAGACGCGGCAAGCGTCGCATCAGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_001295551.1\|2579241_2579877_+\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187560
NZ_CP025753.1\|WP_001045434.1\|2591505_2592090_-\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP025753.1\|WP_000044770.1\|2590730_2591426_-\|molecular-chaperone	unknown	unknown	gnl\|CDD\|225663
NZ_CP025753.1\|WP_001301318.1\|2574720_2575599_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|237968
NZ_CP025753.1\|WP_000147576.1\|2579949_2580990_+\|permease	unknown	unknown	gnl\|CDD\|223773
NZ_CP025753.1\|WP_000037608.1\|2578595_2579114_-\|protein/nucleic-acid-deglycase	unknown	unknown	gnl\|CDD\|153228
NZ_CP025753.1\|WP_000249137.1\|2582742_2584779_-\|penicillin-binding-protein-activator	unknown	unknown	gnl\|CDD\|225649
NZ_CP025753.1\|WP_001295552.1\|2576811_2577336_+\|SCP2-domain-containing-protein	unknown	unknown	gnl\|CDD\|225696
NZ_CP025753.1\|WP_000449030.1\|2578172_2578616_+\|YhbP-family-protein	unknown	unknown	gnl\|CDD\|235127
NZ_CP025753.1\|WP_000246837.1\|2582389_2582785_-\|YraN-family-protein	unknown	unknown	gnl\|CDD\|129354
NZ_CP025753.1\|WP_000189314.1\|2577819_2578122_-\|DNA-damage-response-exodeoxyribonuclease-YhbQ	unknown	unknown	gnl\|CDD\|178979
NZ_CP025753.1\|WP_085949199.1\|2588107_2589381_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|181829
NZ_CP025753.1\|WP_000421305.1\|2575607_2576603_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NZ_CP025753.1\|WP_000646033.1\|2581194_2581770_-\|divisome-associated-lipoprotein-YraP	unknown	unknown	gnl\|CDD\|182907
NZ_CP025753.1\|WP_000130392.1\|2573507_2574515_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182505
NZ_CP025753.1\|WP_000816988.1\|2585746_2586838_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|366088
NZ_CP025753.1\|WP_001158034.1\|2581779_2582370_-\|DnaA-initiator-associating-protein-DiaA	unknown	unknown	gnl\|CDD\|182811
NZ_CP025753.1\|WP_074152315.1\|2592490_2593246_-\|galactosamine-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|182064
NZ_CP025753.1\|WP_000809262.1\|2584843_2585704_+\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|184956
NZ_CP025753.1\|WP_000908569.1\|2577329_2577833_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|225695

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_001295551.1\|2579241_2579877_+\|NAD(P)H-binding-protein	gnl\|CDD\|187560	cd05250, CC3_like_SDR_a, CC3(TIP30)-like, atypical (a) SDRs. Atypical SDRs in this subgroup include CC3 (also known as TIP30) which is implicated in tumor suppression. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine rich NAD(P)-binding motif that resembles the extended SDRs, and have an active site triad of the SDRs (YXXXK and upstream Ser), although the upstream Asn of the usual SDR active site is substituted with Asp. For CC3, the Tyr of the triad is displaced compared to the usual SDRs and the protein is monomeric, both these observations suggest that the usual SDR catalytic activity is not present. NADP appears to serve an important role as a ligand, and may be important in the interaction with other macromolecules. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89133e-65
NZ_CP025753.1\|WP_001045434.1\|2591505_2592090_-\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	1.76746e-31
NZ_CP025753.1\|WP_000044770.1\|2590730_2591426_-\|molecular-chaperone	gnl\|CDD\|225663	COG3121, FimC, P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion].	9.16141e-79
NZ_CP025753.1\|WP_001301318.1\|2574720_2575599_-\|U32-family-peptidase	gnl\|CDD\|237968	PRK15447, PRK15447, putative protease; Provisional.	0
NZ_CP025753.1\|WP_000147576.1\|2579949_2580990_+\|permease	gnl\|CDD\|223773	COG0701, COG0701, Predicted permeases [General function prediction only].	4.38189e-63
NZ_CP025753.1\|WP_000037608.1\|2578595_2579114_-\|protein/nucleic-acid-deglycase	gnl\|CDD\|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	6.06977e-86
NZ_CP025753.1\|WP_000249137.1\|2582742_2584779_-\|penicillin-binding-protein-activator	gnl\|CDD\|225649	COG3107, LppC, Putative lipoprotein [General function prediction only].	6.74472e-141
NZ_CP025753.1\|WP_001295552.1\|2576811_2577336_+\|SCP2-domain-containing-protein	gnl\|CDD\|225696	COG3154, COG3154, Putative lipid carrier protein [Lipid metabolism].	6.78212e-85
NZ_CP025753.1\|WP_000449030.1\|2578172_2578616_+\|YhbP-family-protein	gnl\|CDD\|235127	PRK03467, PRK03467, hypothetical protein; Provisional.	2.19601e-100
NZ_CP025753.1\|WP_000246837.1\|2582389_2582785_-\|YraN-family-protein	gnl\|CDD\|129354	TIGR00252, UPF0102_protein_HI_1656, TIGR00252 family protein. the scores for Mycobacterium tuberculosis and Treponema pallidum are low considering the alignment [Hypothetical proteins, Conserved].	3.92681e-63
NZ_CP025753.1\|WP_000189314.1\|2577819_2578122_-\|DNA-damage-response-exodeoxyribonuclease-YhbQ	gnl\|CDD\|178979	PRK00329, PRK00329, GIY-YIG nuclease superfamily protein; Validated.	3.58629e-45
NZ_CP025753.1\|WP_085949199.1\|2588107_2589381_-\|IS3-family-transposase	gnl\|CDD\|181829	PRK09409, PRK09409, IS2 transposase TnpB; Reviewed.	0
NZ_CP025753.1\|WP_000421305.1\|2575607_2576603_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.87234e-118
NZ_CP025753.1\|WP_000646033.1\|2581194_2581770_-\|divisome-associated-lipoprotein-YraP	gnl\|CDD\|182907	PRK11023, PRK11023, divisome-associated lipoprotein YraP.	1.97056e-117
NZ_CP025753.1\|WP_000130392.1\|2573507_2574515_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|182505	PRK10508, PRK10508, luciferase-like monooxygenase.	0
NZ_CP025753.1\|WP_000816988.1\|2585746_2586838_-\|fimbrial-protein	gnl\|CDD\|366088	pfam00419, Fimbrial, Fimbrial protein.	3.34626e-21
NZ_CP025753.1\|WP_001158034.1\|2581779_2582370_-\|DnaA-initiator-associating-protein-DiaA	gnl\|CDD\|182811	PRK10886, PRK10886, DnaA initiator-associating protein DiaA; Provisional.	5.61903e-143
NZ_CP025753.1\|WP_074152315.1\|2592490_2593246_-\|galactosamine-6-phosphate-isomerase	gnl\|CDD\|182064	PRK09762, PRK09762, galactosamine-6-phosphate isomerase; Provisional.	1.69565e-147
NZ_CP025753.1\|WP_000809262.1\|2584843_2585704_+\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl\|CDD\|184956	PRK14994, PRK14994, SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional.	0
NZ_CP025753.1\|WP_000908569.1\|2577329_2577833_+\|N-acetyltransferase	gnl\|CDD\|225695	COG3153, COG3153, Predicted acetyltransferase [General function prediction only].	5.65062e-64

>NZ_CP025753.1|WP_000147576.1|2579949_2580990_+|permease
MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWEPYYGKAFTAAETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLRTLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPATLVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFSRWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGTVDNSLMWVVAMAVAGCLFVIPTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAVSGVIVGGLALLF
>NZ_CP025753.1|WP_001295551.1|2579241_2579877_+|NAD(P)H-binding-protein
MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNETLFAPLFRLLPGNWKSIDARDVARVMLAESMRPEHEGVTILSSSELRKRAE
>NZ_CP025753.1|WP_000037608.1|2578595_2579114_-|protein/nucleic-acid-deglycase
MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA
>NZ_CP025753.1|WP_000449030.1|2578172_2578616_+|YhbP-family-protein
METLIAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA
>NZ_CP025753.1|WP_000189314.1|2577819_2578122_-|DNA-damage-response-exodeoxyribonuclease-YhbQ
MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPEIKSD
>NZ_CP025753.1|WP_000908569.1|2577329_2577833_+|N-acetyltransferase
MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDSFLTLGLVATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNEFGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEYHEHFNRF
>NZ_CP025753.1|WP_001295552.1|2576811_2577336_+|SCP2-domain-containing-protein
MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQALDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAARKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMKTAPETKQTSVGEPC
>NZ_CP025753.1|WP_000421305.1|2575607_2576603_-|U32-family-peptidase
MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTEKKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEYAAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPLEVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLIDRYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQRSPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQTTLGAYHRKWQ
>NZ_CP025753.1|WP_001301318.1|2574720_2575599_-|U32-family-peptidase
MKYSLGPVLWYWPKETLEEFYQQAATSSADVIYLGEAVCSKRRATKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNMCAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRNQFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLNGIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANSDCNGYWRRLAGLELQA
>NZ_CP025753.1|WP_000130392.1|2573507_2574515_-|LLM-class-flavin-dependent-oxidoreductase
MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRYWLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLYPGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPNVRPVPGYGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKPYAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGVQQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELLG
>NZ_CP025753.1|WP_000646033.1|2581194_2581770_-|divisome-associated-lipoprotein-YraP
MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQVDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVDGANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMGLVTEREAKAAADIASRVSGVKRVTTAFTFIK
>NZ_CP025753.1|WP_001158034.1|2581779_2582370_-|DnaA-initiator-associating-protein-DiaA
MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
>NZ_CP025753.1|WP_000246837.1|2582389_2582785_-|YraN-family-protein
MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
>NZ_CP025753.1|WP_000249137.1|2582742_2584779_-|penicillin-binding-protein-activator
MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDSQRREKTLLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIAQELLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDPDMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTIQQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQPVPVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNVEELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIPRSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATLYASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMGVDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS
>NZ_CP025753.1|WP_000809262.1|2584843_2585704_+|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNALYKYALEQQG
>NZ_CP025753.1|WP_000816988.1|2585746_2586838_-|fimbrial-protein
MKRAPLITGLLLISTSCAYASSGGCGADSTSGATNYSSVVDDVTVNQTDNVTGREFTSATLSSTNWQYACSCSAGKAVKLVYMVSPVLTTTGHQAGYYKLNDSLDIKTTLKANDIPGLVTDQTVSVNTRFTQIKSNTVYSAATQTGVCQGDTSRYGPVNIGANTTFTLYVTKPFLGSMTIPKTDIAVIKGAWVDGMGSPSTGDFHDLVKLSIQGNLTAPQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTSKIKNSLQMRIDGTTGVVDQYNLVARRRSSDNAPDVGIRIENLGGGVANIPFQNGILPVDPSGHGTVNMRAWPVNLVGGELETGKFQGTATITVIVR
>NZ_CP025753.1|WP_085949199.1|2588107_2589381_-|IS3-family-transposase
MIVLILVFRLVIGEQMIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVEYGRGKKVDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWKDGRRSRHSDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRIYRIMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHWAVTTGGFNSETVQDVMLGAVERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISVMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQQASNGLSDNRCLEI
>NZ_CP025753.1|WP_000044770.1|2590730_2591426_-|molecular-chaperone
MSKRTFAVIITLLCSFCIGQALAGGIVLQRTRVIYDASRKEAALPVANKGAETPYLLQSWVDNIDGTSRAPFIITPPLFRLEAGDDSSLRIIKTADNLPENKESLFYINVRAIPAKKKSDNVNANELTLVFKTRIKMFYRPAHLKGRVNDAWKSLEFKRSDHSLNIYNPTEYYVVFAGLAVDKTDLTSKIEYIAPGEHKQLPLPASGGKNVKWAAINDYGGSSGTETRPLQ
>NZ_CP025753.1|WP_001045434.1|2591505_2592090_-|type-1-fimbrial-protein
MNKVTKTAIAGLLALFAGNAAATDGEIVFDGEILKSACEINDSDKKIEVALGHYNAEQFRSVGDRSPKIPFTIPLVNCPVTGWEHDNGNVEASFRLWLETRDNGTVPNFPNLAKVGSFAGTAATGVGIRIDDAESGNLMPLNAMGNDNTVYQIPADSAGIVNVDLIAYYVSTVEASEITPGEADAVVNVTLDYR
>NZ_CP025753.1|WP_074152315.1|2592490_2593246_-|galactosamine-6-phosphate-isomerase
MERGTASGSASLLKEFHPVQTLQQVENYTALSERASEYLLAVIRSKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETFLQQHIVQPLGLREDQLISFRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLNEPGESLQPACHISQLDARTQQHEMLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGKQDATERFLTAKVSTAIPASFLWLHSNFICLINT

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Crispr_ID: NZ_CP025753_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_7

2626396-2626513

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025753_7

>merge|NZ_CP025753|7|2626396-2626513|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>NZ_CP025753|7|6|2626396-2626513|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_000531214.1\|2629782_2630769_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223512
NZ_CP025753.1\|WP_001297155.1\|2630838_2631321_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP025753.1\|WP_000104211.1\|2614650_2615589_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP025753.1\|WP_001295544.1\|2626586_2626751_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025753.1\|WP_000031415.1\|2632112_2632418_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP025753.1\|WP_000622115.1\|2622066_2623431_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP025753.1\|WP_000861734.1\|2619297_2621592_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NZ_CP025753.1\|WP_000384145.1\|2629124_2629490_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP025753.1\|WP_000401598.1\|2623705_2625037_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP025753.1\|WP_001041010.1\|2627579_2628476_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
NZ_CP025753.1\|WP_000719990.1\|2621605_2621995_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP025753.1\|WP_000633577.1\|2626773_2627475_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP025753.1\|WP_000096086.1\|2631416_2631716_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP025753.1\|WP_001352528.1\|2618055_2619264_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP025753.1\|WP_000785722.1\|2631705_2632110_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP025753.1\|WP_000145840.1\|2614117_2614462_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP025753.1\|WP_000107723.1\|2616698_2618030_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP025753.1\|WP_000548347.1\|2615687_2616677_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP025753.1\|WP_001198780.1\|2628526_2628883_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP025753.1\|WP_000460519.1\|2625064_2626375_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_000622115.1\|2622066_2623431_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP025753.1\|WP_000531214.1\|2629782_2630769_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP025753.1\|WP_000104211.1\|2614650_2615589_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP025753.1\|WP_001297155.1\|2630838_2631321_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.8408e-29
NZ_CP025753.1\|WP_000031415.1\|2632112_2632418_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP025753.1\|WP_000633577.1\|2626773_2627475_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.02982e-67
NZ_CP025753.1\|WP_000861734.1\|2619297_2621592_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP025753.1\|WP_000384145.1\|2629124_2629490_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
NZ_CP025753.1\|WP_000401598.1\|2623705_2625037_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53913e-167
NZ_CP025753.1\|WP_001041010.1\|2627579_2628476_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
NZ_CP025753.1\|WP_000719990.1\|2621605_2621995_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP025753.1\|WP_000096086.1\|2631416_2631716_-\|hypothetical-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP025753.1\|WP_001352528.1\|2618055_2619264_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP025753.1\|WP_000785722.1\|2631705_2632110_-\|hypothetical-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP025753.1\|WP_000145840.1\|2614117_2614462_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	8.0507e-67
NZ_CP025753.1\|WP_000107723.1\|2616698_2618030_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP025753.1\|WP_000548347.1\|2615687_2616677_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP025753.1\|WP_001198780.1\|2628526_2628883_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35
NZ_CP025753.1\|WP_000460519.1\|2625064_2626375_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0

>NZ_CP025753.1|WP_000460519.1|2625064_2626375_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP025753.1|WP_000401598.1|2623705_2625037_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP025753.1|WP_000622115.1|2622066_2623431_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP025753.1|WP_000719990.1|2621605_2621995_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP025753.1|WP_000861734.1|2619297_2621592_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP025753.1|WP_001352528.1|2618055_2619264_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVVIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP025753.1|WP_000107723.1|2616698_2618030_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP025753.1|WP_000548347.1|2615687_2616677_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP025753.1|WP_000104211.1|2614650_2615589_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP025753.1|WP_000145840.1|2614117_2614462_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSVINNAACHIFSRYLLENKHLFYQYFKISNTCIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP025753.1|WP_001295544.1|2626586_2626751_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP025753.1|WP_000633577.1|2626773_2627475_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>NZ_CP025753.1|WP_001041010.1|2627579_2628476_+|LysR-family-transcriptional-regulator
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>NZ_CP025753.1|WP_001198780.1|2628526_2628883_-|DUF805-domain-containing-protein
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>NZ_CP025753.1|WP_000384145.1|2629124_2629490_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP025753.1|WP_000531214.1|2629782_2630769_-|glutathione-S-transferase-family-protein
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDTLGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP025753.1|WP_001297155.1|2630838_2631321_-|DoxX-family-protein
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP025753.1|WP_000096086.1|2631416_2631716_-|hypothetical-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP025753.1|WP_000785722.1|2631705_2632110_-|hypothetical-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP025753.1|WP_000031415.1|2632112_2632418_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: NZ_CP025753_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_8

3055500-3055955

Orphan

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

7 spacers

The CRISPR arrays of NZ_CP025753_8

>merge|NZ_CP025753|8|3055500-3055955|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCGTCCACGCTGTAACGGCCATCATTAAGTTTAGTGAGTTCCCCGCGCCAGCGGGGATAAACCGGCTGATGGTCTGGGAGTGTCCATCGGGCAACTGAGTTCCCCGCGCCAGCGGGGATAAACCGGAAGTAGGCCTGACAGTGATTGAACGCATACTGAGTTCCCCGCGCCAGCGGGGATAAACCGAGTTGGGGCGGCGCAATAACGAGACGATACGCGAGTTCCCCGCGCCAGCGGGGATAAACCGGGGAGTGGCACTTCTGGGGTAGCGGCGGCCCTGAGTTCCCCGCGCCAGCGGGGATAAACCGTCAACGCGCTCAGACGTTGCGTGAGTGAACCAGAGTTCCCCGCGCCAGCGGGGATAAACCGCCCGGAATGCATTCTGAAGGTTTGCTGTATATGAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP025753|8|2|3055500-3055955|PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCCACGCTGTAACGGCCATCATTAAGTTTAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCTGATGGTCTGGGAGTGTCCATCGGGCAACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAAGTAGGCCTGACAGTGATTGAACGCATACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTGGGGCGGCGCAATAACGAGACGATACGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGAGTGGCACTTCTGGGGTAGCGGCGGCCCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAACGCGCTCAGACGTTGCGTGAGTGAACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGGAATGCATTCTGAAGGTTTGCTGTATAT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP025753|8|7|3055500-3055955|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCCACGCTGTAACGGCCATCATTAAGTTTAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCTGATGGTCTGGGAGTGTCCATCGGGCAACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAAGTAGGCCTGACAGTGATTGAACGCATACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTGGGGCGGCGCAATAACGAGACGATACGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGAGTGGCACTTCTGGGGTAGCGGCGGCCCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAACGCGCTCAGACGTTGCGTGAGTGAACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGGAATGCATTCTGAAGGTTTGCTGTATAT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP025753|8|1|3055500-3055955|CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCCACGCTGTAACGGCCATCATTAAGTTTAGT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GCTGATGGTCTGGGAGTGTCCATCGGGCAACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAAGTAGGCCTGACAGTGATTGAACGCATACT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTGGGGCGGCGCAATAACGAGACGATACGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGGAGTGGCACTTCTGGGGTAGCGGCGGCCCT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCAACGCGCTCAGACGTTGCGTGAGTGAACCA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGGAATGCATTCTGAAGGTTTGCTGTATAT
GAGTTCCCCGCGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_000039684.1\|3056592_3058071_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP025753.1\|WP_000254738.1\|3048815_3049151_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP025753.1\|WP_001098105.1\|3062096_3063434_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP025753.1\|WP_000226815.1\|3046255_3048490_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP025753.1\|WP_001199979.1\|3054488_3055160_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP025753.1\|WP_001164578.1\|3058097_3059375_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP025753.1\|WP_001071648.1\|3049221_3050013_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP025753.1\|WP_001288227.1\|3054209_3054350_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025753.1\|WP_000109532.1\|3065787_3066048_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP025753.1\|WP_000581937.1\|3048567_3048816_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP025753.1\|WP_000046812.1\|3044906_3046208_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP025753.1\|WP_000210878.1\|3050240_3051878_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP025753.1\|WP_001384738.1\|3064187_3065048_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP025753.1\|WP_000021330.1\|3059693_3060479_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP025753.1\|WP_001130266.1\|3065195_3065771_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP025753.1\|WP_001268446.1\|3053323_3054196_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP025753.1\|WP_000036723.1\|3051965_3053264_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP025753.1\|WP_001324445.1\|3063411_3064191_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP025753.1\|WP_000059312.1\|3060548_3062003_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP025753.1\|WP_001295150.1\|3066038_3067310_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_000039684.1\|3056592_3058071_-\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.13296e-107
NZ_CP025753.1\|WP_000254738.1\|3048815_3049151_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP025753.1\|WP_000226815.1\|3046255_3048490_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP025753.1\|WP_001199979.1\|3054488_3055160_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.23739e-155
NZ_CP025753.1\|WP_001098105.1\|3062096_3063434_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
NZ_CP025753.1\|WP_001268446.1\|3053323_3054196_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	5.56011e-100
NZ_CP025753.1\|WP_001164578.1\|3058097_3059375_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.84544e-29
NZ_CP025753.1\|WP_000109532.1\|3065787_3066048_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	3.6328e-41
NZ_CP025753.1\|WP_000581937.1\|3048567_3048816_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP025753.1\|WP_000046812.1\|3044906_3046208_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP025753.1\|WP_000210878.1\|3050240_3051878_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP025753.1\|WP_001384738.1\|3064187_3065048_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	6.38228e-89
NZ_CP025753.1\|WP_000021330.1\|3059693_3060479_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.14687e-138
NZ_CP025753.1\|WP_001130266.1\|3065195_3065771_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP025753.1\|WP_001071648.1\|3049221_3050013_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP025753.1\|WP_000036723.1\|3051965_3053264_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP025753.1\|WP_001324445.1\|3063411_3064191_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	7.46503e-62
NZ_CP025753.1\|WP_000059312.1\|3060548_3062003_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.25325e-82
NZ_CP025753.1\|WP_001295150.1\|3066038_3067310_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	2.82789e-125

>NZ_CP025753.1|WP_001199979.1|3054488_3055160_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVISRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP025753.1|WP_001288227.1|3054209_3054350_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNESKITDAAVNLFIQI
>NZ_CP025753.1|WP_001268446.1|3053323_3054196_-|YgcG-family-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIKVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVCISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASGRW
>NZ_CP025753.1|WP_000036723.1|3051965_3053264_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP025753.1|WP_000210878.1|3050240_3051878_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP025753.1|WP_001071648.1|3049221_3050013_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP025753.1|WP_000254738.1|3048815_3049151_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP025753.1|WP_000581937.1|3048567_3048816_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP025753.1|WP_000226815.1|3046255_3048490_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP025753.1|WP_000046812.1|3044906_3046208_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP025753.1|WP_000039684.1|3056592_3058071_-|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNYFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFMPVESNAKRYDAMNKGIFKDLTRHTDVILKKSYEVMHGELGNADSIQSWSNA
>NZ_CP025753.1|WP_001164578.1|3058097_3059375_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALGMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP025753.1|WP_000021330.1|3059693_3060479_+|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAASCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP025753.1|WP_000059312.1|3060548_3062003_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP025753.1|WP_001098105.1|3062096_3063434_+|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP025753.1|WP_001324445.1|3063411_3064191_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWRDYLRQRMQP
>NZ_CP025753.1|WP_001384738.1|3064187_3065048_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLIIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPKVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP025753.1|WP_001130266.1|3065195_3065771_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP025753.1|WP_000109532.1|3065787_3066048_-|ferredoxin-family-protein
MSVARNLWRVADAPHIVPADSVERQTAERLISACPAGLFSLTPEGDLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP025753.1|WP_001295150.1|3066038_3067310_-|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERCITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: NZ_CP025753_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_9

3083002-3083885

TypeI-E

I-E

Consensus_repeat	Method
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

14 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP025753_9

>merge|NZ_CP025753|9|3083002-3083885|CRISPRCasFinder,PILER-CR,CRT
TGTGTTCCCCGCGCCAGCGGGGATAAACCGTTGCCCGCGCAATTCCGGGAGCATCCGCAATTGTGTTCCCCGCGCCAGCGGGGATAAACCGACGGACAAAATATATATTGATTTGCGAATTATGTGTTCCCCGCGCCAGCGGGGATAAACCGGTAAAGAAACTGCCGACAAATCCCTGTTCGTTGTGTTCCCCGCGCCAGCGGGGATAAACCGCCCGTCACCGACGCGCAGTGGCGCTACCGTGAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCTACGAACAATTCCTCTGAACCGCCCGCACTGTGTTCCCCGCGCCAGCGGGGATAAACCGGGATCTAACGCGCTGTAAAAATTCCGTGCTTTGTGTTCCCCGCGCCAGCGGGGATAAACCGCTAACGCCACATTGGCGGAATTGGCTGCTGATGTGTTCCCCGCGCCAGCGGGGATAAACCATGCGGATTACCGGCAAAACATGGGAGCAAACCGTGTTCCCCGCGCCAGCGGGGATAAACCGCCGAACGGCTGGCGAAGCAGGTGGCTGGCGTAGTGTTCCCCGCGCCAGCGGGGATAAACCGGTTTACCGCCCCGCAGAGGCGCTGGCAGATCCGTGTTCCCCGCGCCAGCGGGGATAAACCGGGATGACCTGTCGCTAAAACTCGCCGCGTACAGTGTTCCCCGCGCCAGCGGGGATAAACCGTCCGTTTGGTCCACCAAATGTTTGATGCTTCAGTGTTCCCCGCGCCAGCGGGGATAAACCGTTCAGGGTGTGATTCCGCATACCAAGCAGTAAGAGTTCCCCGCGCCAGCGGGGATAAACCGGGCGCACTGGATGCGATGATGGATATCACTTAGAATTCCCCGCCCCTGCGGTAGAACACCC

>NZ_CP025753|9|8|3083002-3083824|CRISPRCasFinder
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCCCGCGCAATTCCGGGAGCATCCGCAAT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGACAAAATATATATTGATTTGCGAATTA
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAAAGAAACTGCCGACAAATCCCTGTTCGT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTCACCGACGCGCAGTGGCGCTACCGTG
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	CCTACGAACAATTCCTCTGAACCGCCCGCAC
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATCTAACGCGCTGTAAAAATTCCGTGCTT
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	CTAACGCCACATTGGCGGAATTGGCTGCTGA
TGTGTTCCCCGCGCCAGCGGGGATAAACCA	TGCGGATTACCGGCAAAACATGGGAGCAAAC
CGTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAACGGCTGGCGAAGCAGGTGGCTGGCGT
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTTACCGCCCCGCAGAGGCGCTGGCAGATC
CGTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATGACCTGTCGCTAAAACTCGCCGCGTAC
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	TCCGTTTGGTCCACCAAATGTTTGATGCTTC
AGTGTTCCCCGCGCCAGCGGGGATAAACCG	TTCAGGGTGTGATTCCGCATACCAAGCAGTA
AGAGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP025753|9|3|3083003-3083824|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCCCGCGCAATTCCGGGAGCATCCGCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGACAAAATATATATTGATTTGCGAATTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAAAGAAACTGCCGACAAATCCCTGTTCGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTCACCGACGCGCAGTGGCGCTACCGTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCTACGAACAATTCCTCTGAACCGCCCGCACT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATCTAACGCGCTGTAAAAATTCCGTGCTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTAACGCCACATTGGCGGAATTGGCTGCTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCA	TGCGGATTACCGGCAAAACATGGGAGCAAACC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAACGGCTGGCGAAGCAGGTGGCTGGCGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTTACCGCCCCGCAGAGGCGCTGGCAGATCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATGACCTGTCGCTAAAACTCGCCGCGTACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCCGTTTGGTCCACCAAATGTTTGATGCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTCAGGGTGTGATTCCGCATACCAAGCAGTAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP025753|9|2|3083003-3083885|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTGCCCGCGCAATTCCGGGAGCATCCGCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGACAAAATATATATTGATTTGCGAATTAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTAAAGAAACTGCCGACAAATCCCTGTTCGTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCCGTCACCGACGCGCAGTGGCGCTACCGTGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCTACGAACAATTCCTCTGAACCGCCCGCACT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATCTAACGCGCTGTAAAAATTCCGTGCTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTAACGCCACATTGGCGGAATTGGCTGCTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCA	TGCGGATTACCGGCAAAACATGGGAGCAAACC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAACGGCTGGCGAAGCAGGTGGCTGGCGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTTTACCGCCCCGCAGAGGCGCTGGCAGATCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGATGACCTGTCGCTAAAACTCGCCGCGTACA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCCGTTTGGTCCACCAAATGTTTGATGCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTCAGGGTGTGATTCCGCATACCAAGCAGTAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGCGCACTGGATGCGATGATGGATATCACTTA
GAATTCCCCGCCCCTGCGGTAGAACACCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_001233970.1\|3074347_3077047_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP025753.1\|WP_000281446.1\|3081045_3081696_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP025753.1\|WP_001219242.1\|3089743_3090223_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP025753.1\|WP_000144861.1\|3081692_3082616_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP025753.1\|WP_000029329.1\|3078703_3079240_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP025753.1\|WP_000372108.1\|3085194_3086103_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP025753.1\|WP_001090387.1\|3086104_3087532_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP025753.1\|WP_001246104.1\|3088186_3088510_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP025753.1\|WP_001173673.1\|3087531_3088137_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP025753.1\|WP_000568943.1\|3090219_3091269_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP025753.1\|WP_001300563.1\|3072997_3074110_-\|IS4-like-element-IS421-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP025753.1\|WP_000206443.1\|3079251_3080307_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP025753.1\|WP_001084084.1\|3077144_3078707_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP025753.1\|WP_000490426.1\|3083905_3084943_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP025753.1\|WP_000956458.1\|3072652_3072805_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP025753.1\|WP_001295182.1\|3091249_3092011_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP025753.1\|WP_000517476.1\|3088703_3089015_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP025753.1\|WP_000063176.1\|3082612_3082906_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP025753.1\|WP_000246138.1\|3089033_3089744_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP025753.1\|WP_000085051.1\|3080317_3081064_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_001233970.1\|3074347_3077047_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.23832e-176
NZ_CP025753.1\|WP_000281446.1\|3081045_3081696_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.0289e-91
NZ_CP025753.1\|WP_001219242.1\|3089743_3090223_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP025753.1\|WP_000144861.1\|3081692_3082616_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	6.67486e-158
NZ_CP025753.1\|WP_000029329.1\|3078703_3079240_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	1.12087e-29
NZ_CP025753.1\|WP_000372108.1\|3085194_3086103_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP025753.1\|WP_001090387.1\|3086104_3087532_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP025753.1\|WP_001246104.1\|3088186_3088510_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP025753.1\|WP_001173673.1\|3087531_3088137_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP025753.1\|WP_000568943.1\|3090219_3091269_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP025753.1\|WP_001300563.1\|3072997_3074110_-\|IS4-like-element-IS421-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.16058e-15
NZ_CP025753.1\|WP_000206443.1\|3079251_3080307_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	5.21697e-155
NZ_CP025753.1\|WP_001084084.1\|3077144_3078707_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP025753.1\|WP_000490426.1\|3083905_3084943_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP025753.1\|WP_000956458.1\|3072652_3072805_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP025753.1\|WP_001295182.1\|3091249_3092011_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP025753.1\|WP_000517476.1\|3088703_3089015_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP025753.1\|WP_000063176.1\|3082612_3082906_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP025753.1\|WP_000246138.1\|3089033_3089744_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP025753.1\|WP_000085051.1\|3080317_3081064_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	5.83917e-49

>NZ_CP025753.1|WP_000063176.1|3082612_3082906_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP025753.1|WP_000144861.1|3081692_3082616_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP025753.1|WP_000281446.1|3081045_3081696_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELRTGQQLCFNLRANPTICKSGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP025753.1|WP_000085051.1|3080317_3081064_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTIQMPKEVRKARYFSRREELSDPDLLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>NZ_CP025753.1|WP_000206443.1|3079251_3080307_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWAMAEKGTEQPRSLAAAFYEPINGTRQLEVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP025753.1|WP_000029329.1|3078703_3079240_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP025753.1|WP_001084084.1|3077144_3078707_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKDHRRWDDIWEDGLEVEKLREALLSLEHAFQFGPDSPSFMQDFEALTGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEYLCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKMWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQNDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRFVRQIEEGQDADELLSKWNKEIWLFARQDFDERVFTNPYEPVNLERIMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP025753.1|WP_001233970.1|3074347_3077047_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKEGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGRPPDRMDELDNFLPEDKAAARDFLLAIKALFPRIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAQAMDIKHYWQKALVQAQNALTVFPPKAETAPFTGINTLFPFIENPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGAEGQQEAPLLGKDDYPWLTHVTKTDVHSHRVATRKEVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKEDGSQRAGKVLICTQVLEQSVDCDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHSARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRARAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGDAFRQWCIEQRQDPEMANVILVTDDESCGYSAMEGLTGKVG
>NZ_CP025753.1|WP_001300563.1|3072997_3074110_-|IS4-like-element-IS421-family-transposase
MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLLRLGLAYGPGGMSLREVTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAVTGCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFAQTADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGLDCGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQAETLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPELAKAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN
>NZ_CP025753.1|WP_000956458.1|3072652_3072805_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP025753.1|WP_000490426.1|3083905_3084943_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP025753.1|WP_000372108.1|3085194_3086103_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP025753.1|WP_001090387.1|3086104_3087532_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEKTFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMAWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFINRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP025753.1|WP_001173673.1|3087531_3088137_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP025753.1|WP_001246104.1|3088186_3088510_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP025753.1|WP_000517476.1|3088703_3089015_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP025753.1|WP_000246138.1|3089033_3089744_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP025753.1|WP_001219242.1|3089743_3090223_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP025753.1|WP_000568943.1|3090219_3091269_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP025753.1|WP_001295182.1|3091249_3092011_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP025753_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025753_10

3610644-3610785

Orphan

Consensus_repeat	Method
CGCGTCTTATCAGGCCTACAAATCCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025753_10

>merge|NZ_CP025753|10|3610644-3610785|CRISPRCasFinder
CGCGTCTTATCAGGCCTACAAATCCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAATCCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>NZ_CP025753|10|9|3610644-3610785|CRISPRCasFinder
CGCGTCTTATCAGGCCTACAAATCCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGATGCGACGCTGG
CGCGTCTTATCAGGCCTACAAATCCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025753.1\|WP_000786527.1\|3630661_3631846_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
NZ_CP025753.1\|WP_000012285.1\|3621310_3622999_+\|DUF2138-domain-containing-protein	unknown	unknown	gnl\|CDD\|227030
NZ_CP025753.1\|WP_001209922.1\|3600716_3601976_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	unknown	unknown	gnl\|CDD\|225617
NZ_CP025753.1\|WP_000140570.1\|3598433_3599336_-\|ISNCY-family-transposase	unknown	unknown	gnl\|CDD\|182167
NZ_CP025753.1\|WP_001323797.1\|3622995_3623619_+\|DUF1175-domain-containing-protein	unknown	unknown	gnl\|CDD\|225774
NZ_CP025753.1\|WP_001104509.1\|3628157_3629807_+\|DUF2300-domain-containing-protein	unknown	unknown	gnl\|CDD\|227732
NZ_CP025753.1\|WP_000301049.1\|3608481_3609132_+\|lipopolysaccharide-kinase-InaA	unknown	unknown	gnl\|CDD\|182136
NZ_CP025753.1\|WP_000948732.1\|3603866_3605225_+\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
NZ_CP025753.1\|WP_001000358.1\|3599529_3600720_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
NZ_CP025753.1\|WP_001774571.1\|3623762_3628157_+\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NZ_CP025753.1\|WP_000990753.1\|3617665_3618388_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	unknown	unknown	gnl\|CDD\|235350
NZ_CP025753.1\|WP_001281242.1\|3618534_3621162_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	unknown	unknown	gnl\|CDD\|235502
NZ_CP025753.1\|WP_001134031.1\|3606524_3607595_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025753.1\|WP_001220072.1\|3613785_3617538_+\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	unknown	unknown	gnl\|CDD\|182059
NZ_CP025753.1\|WP_001225888.1\|3629811_3630588_+\|YfaP-family-protein	unknown	unknown	gnl\|CDD\|227021
NZ_CP025753.1\|WP_000779091.1\|3605229_3606306_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
NZ_CP025753.1\|WP_000135040.1\|3609185_3609440_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	unknown	unknown	gnl\|CDD\|182668
NZ_CP025753.1\|WP_000332036.1\|3609439_3610570_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|181647
NZ_CP025753.1\|WP_001075172.1\|3610804_3613090_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181649
NZ_CP025753.1\|WP_000857257.1\|3601965_3603594_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847

Protein	Function_ID	Function_description	E-value
NZ_CP025753.1\|WP_000786527.1\|3630661_3631846_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NZ_CP025753.1\|WP_000012285.1\|3621310_3622999_+\|DUF2138-domain-containing-protein	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_CP025753.1\|WP_001209922.1\|3600716_3601976_-\|glycerol-3-phosphate-dehydrogenase-subunit-GlpB	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
NZ_CP025753.1\|WP_000140570.1\|3598433_3599336_-\|ISNCY-family-transposase	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	0
NZ_CP025753.1\|WP_001323797.1\|3622995_3623619_+\|DUF1175-domain-containing-protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	1.22167e-137
NZ_CP025753.1\|WP_001104509.1\|3628157_3629807_+\|DUF2300-domain-containing-protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	2.34326e-127
NZ_CP025753.1\|WP_000301049.1\|3608481_3609132_+\|lipopolysaccharide-kinase-InaA	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	1.43283e-158
NZ_CP025753.1\|WP_000948732.1\|3603866_3605225_+\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
NZ_CP025753.1\|WP_001000358.1\|3599529_3600720_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
NZ_CP025753.1\|WP_001774571.1\|3623762_3628157_+\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NZ_CP025753.1\|WP_000990753.1\|3617665_3618388_-\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	1.58484e-171
NZ_CP025753.1\|WP_001281242.1\|3618534_3621162_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NZ_CP025753.1\|WP_001220072.1\|3613785_3617538_+\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
NZ_CP025753.1\|WP_001225888.1\|3629811_3630588_+\|YfaP-family-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	6.03617e-152
NZ_CP025753.1\|WP_000779091.1\|3605229_3606306_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
NZ_CP025753.1\|WP_000135040.1\|3609185_3609440_-\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
NZ_CP025753.1\|WP_000332036.1\|3609439_3610570_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
NZ_CP025753.1\|WP_001075172.1\|3610804_3613090_-\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
NZ_CP025753.1\|WP_000857257.1\|3601965_3603594_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0

>NZ_CP025753.1|WP_000332036.1|3609439_3610570_-|ribonucleotide-diphosphate-reductase-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL
>NZ_CP025753.1|WP_000135040.1|3609185_3609440_-|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>NZ_CP025753.1|WP_000301049.1|3608481_3609132_+|lipopolysaccharide-kinase-InaA
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYVKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>NZ_CP025753.1|WP_001134031.1|3606524_3607595_-|hypothetical-protein
MPNTSIHLSRCNILQNNKLQPEEVYKESQQTAKLEIFCDEFLKISQSRYGLSTSADSIANLLTFFTKASDAIDRIKTQKIDVHSYGFVPIRHFVEHVITYKNEFAADYEPYTLTFTRGENNEGVLSIESKEGSISQRTINLNEYETAINIINEHVTKENIHNTVQSLTEKDISKINSSDKHHKISSEESIKSQLYSDQKKYADLLLHSEKNTEWYKYASSEERYDKFKNSSKEIKNTYKQIVLAQKKLNQMKYINKLGGELIDIADKKLAPLINDSFSYTRDFFAYSKQENNIFTFDNSKFVDPKEKEGLMIQHSNGQLVITGKYCPEGVQTAFTQEQYDKLIRHINIFFTFPKCE
>NZ_CP025753.1|WP_000779091.1|3605229_3606306_+|glycerophosphodiester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMELNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>NZ_CP025753.1|WP_000948732.1|3603866_3605225_+|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRNGG
>NZ_CP025753.1|WP_000857257.1|3601965_3603594_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>NZ_CP025753.1|WP_001209922.1|3600716_3601976_-|glycerol-3-phosphate-dehydrogenase-subunit-GlpB
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRATWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDQTLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>NZ_CP025753.1|WP_001000358.1|3599529_3600720_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVITDCETCKWQIEMSTSLRCEHPITLLAQALA
>NZ_CP025753.1|WP_000140570.1|3598433_3599336_-|ISNCY-family-transposase
MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAAMQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDITIVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQCGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLEQGIDRDQVLAATQLSEADLAANNH
>NZ_CP025753.1|WP_001075172.1|3610804_3613090_-|ribonucleoside-diphosphate-reductase-subunit-alpha
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>NZ_CP025753.1|WP_001220072.1|3613785_3617538_+|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC
MRIIFLRKEYLSLLPSMIASLFSANGVAAVTDSCQGYDVKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIVNNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQNQAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADILHYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFSNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>NZ_CP025753.1|WP_000990753.1|3617665_3618388_-|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>NZ_CP025753.1|WP_001281242.1|3618534_3621162_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>NZ_CP025753.1|WP_000012285.1|3621310_3622999_+|DUF2138-domain-containing-protein
MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETIPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIASDLLSGKKRWQASFGLEERAAEKTPVRQRIVASARLLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGIAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>NZ_CP025753.1|WP_001323797.1|3622995_3623619_+|DUF1175-domain-containing-protein
MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANEALKVHDSKWLKSNGIASQYLPPEMTLKPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWILNDSNPNFIGIYRLNFLAR
>NZ_CP025753.1|WP_001774571.1|3623762_3628157_+|alpha-2-macroglobulin-family-protein
MRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQAKPFEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGKELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVIGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVTLNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVRVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQAIGVTQQPEYWQHMLDSYAEQADNVPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDPSDINDSLIFDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYARDKAANSNQPLAHTVVLLNSGGDATQTAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>NZ_CP025753.1|WP_001104509.1|3628157_3629807_+|DUF2300-domain-containing-protein
MNWRRIVWLLALVTLPTLAEETPLQLALRGAQHDQLYQLSSSGVTKVSALPDTLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTAVKPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMAAWTQDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKKKPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>NZ_CP025753.1|WP_001225888.1|3629811_3630588_+|YfaP-family-protein
MRKIFLPLLLVALSPVVHSEGVQEVEIDAPLSGWHPVEGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>NZ_CP025753.1|WP_000786527.1|3630661_3631846_-|acetyl-CoA-C-acetyltransferase
MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSLHIDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKTLGFDPEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP025753_1	1.1\|145810\|40\|NZ_CP025753\|CRISPRCasFinder	145810-145849	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
NZ_CP025753_5	5.1\|1141837\|42\|NZ_CP025753\|PILER-CR	1141837-1141878	42	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141085-141126	0	1.0
NZ_CP025753_5	5.2\|1141896\|40\|NZ_CP025753\|PILER-CR	1141896-1141935	40	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141028-141067	1	0.975
NZ_CP025753_3	3.1\|908976\|48\|NZ_CP025753\|CRISPRCasFinder	908976-909023	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4089-4136	3	0.938
NZ_CP025753_3	3.1\|908976\|48\|NZ_CP025753\|CRISPRCasFinder	908976-909023	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4088-4135	3	0.938
NZ_CP025753_3	3.1\|908976\|48\|NZ_CP025753\|CRISPRCasFinder	908976-909023	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4088-4135	3	0.938
NZ_CP025753_3	3.1\|908976\|48\|NZ_CP025753\|CRISPRCasFinder	908976-909023	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4088-4135	3	0.938
NZ_CP025753_9	9.27\|3083825\|32\|NZ_CP025753\|CRT	3083825-3083856	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	3	0.906
NZ_CP025753_6	6.1\|2581091\|42\|NZ_CP025753\|CRISPRCasFinder	2581091-2581132	42	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30214-30255	7	0.833
NZ_CP025753_9	9.1\|3083032\|31\|NZ_CP025753\|CRISPRCasFinder	3083032-3083062	31	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	62682-62712	7	0.774
NZ_CP025753_9	9.1\|3083032\|31\|NZ_CP025753\|CRISPRCasFinder	3083032-3083062	31	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1222106-1222136	7	0.774
NZ_CP025753_9	9.1\|3083032\|31\|NZ_CP025753\|CRISPRCasFinder	3083032-3083062	31	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	2467672-2467702	7	0.774
NZ_CP025753_9	9.4\|3083215\|31\|NZ_CP025753\|CRISPRCasFinder	3083215-3083245	31	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	17977-18007	7	0.774
NZ_CP025753_9	9.9\|3083520\|31\|NZ_CP025753\|CRISPRCasFinder	3083520-3083550	31	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	530641-530671	7	0.774
NZ_CP025753_9	9.27\|3083825\|32\|NZ_CP025753\|CRT	3083825-3083856	32	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	112768-112799	7	0.781
NZ_CP025753_6	6.1\|2581091\|42\|NZ_CP025753\|CRISPRCasFinder	2581091-2581132	42	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	24899-24940	8	0.81
NZ_CP025753_8	8.6\|3055834\|32\|NZ_CP025753\|PILER-CR,CRISPRCasFinder,CRT	3055834-3055865	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1417960-1417991	8	0.75
NZ_CP025753_9	9.4\|3083215\|31\|NZ_CP025753\|CRISPRCasFinder	3083215-3083245	31	NZ_CP017753	Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence	97498-97528	8	0.742
NZ_CP025753_9	9.7\|3083398\|31\|NZ_CP025753\|CRISPRCasFinder	3083398-3083428	31	NZ_CP044456	Acinetobacter indicus strain B18 plasmid pB18-1, complete sequence	83495-83525	8	0.742
NZ_CP025753_9	9.7\|3083398\|31\|NZ_CP025753\|CRISPRCasFinder	3083398-3083428	31	NZ_CP039144	Acinetobacter sp. 10FS3-1 plasmid p10FS3-1-1, complete sequence	301179-301209	8	0.742
NZ_CP025753_9	9.9\|3083520\|31\|NZ_CP025753\|CRISPRCasFinder	3083520-3083550	31	NZ_CP036297	Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence	14953-14983	8	0.742
NZ_CP025753_9	9.9\|3083520\|31\|NZ_CP025753\|CRISPRCasFinder	3083520-3083550	31	NZ_CP036288	Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence	14983-15013	8	0.742
NZ_CP025753_9	9.9\|3083520\|31\|NZ_CP025753\|CRISPRCasFinder	3083520-3083550	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	3454-3484	8	0.742
NZ_CP025753_9	9.9\|3083520\|31\|NZ_CP025753\|CRISPRCasFinder	3083520-3083550	31	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	148992-149022	8	0.742
NZ_CP025753_9	9.14\|3083032\|32\|NZ_CP025753\|PILER-CR,CRT	3083032-3083063	32	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	62682-62713	8	0.75
NZ_CP025753_9	9.14\|3083032\|32\|NZ_CP025753\|PILER-CR,CRT	3083032-3083063	32	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1222106-1222137	8	0.75
NZ_CP025753_9	9.14\|3083032\|32\|NZ_CP025753\|PILER-CR,CRT	3083032-3083063	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	2467671-2467702	8	0.75
NZ_CP025753_9	9.14\|3083032\|32\|NZ_CP025753\|PILER-CR,CRT	3083032-3083063	32	NC_008759	Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence	12670-12701	8	0.75
NZ_CP025753_9	9.17\|3083215\|32\|NZ_CP025753\|PILER-CR,CRT	3083215-3083246	32	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	17977-18008	8	0.75
NZ_CP025753_9	9.17\|3083215\|32\|NZ_CP025753\|PILER-CR,CRT	3083215-3083246	32	NZ_CP017753	Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence	97497-97528	8	0.75
NZ_CP025753_9	9.20\|3083398\|32\|NZ_CP025753\|PILER-CR,CRT	3083398-3083429	32	NZ_CP044456	Acinetobacter indicus strain B18 plasmid pB18-1, complete sequence	83495-83526	8	0.75
NZ_CP025753_9	9.20\|3083398\|32\|NZ_CP025753\|PILER-CR,CRT	3083398-3083429	32	NZ_CP039144	Acinetobacter sp. 10FS3-1 plasmid p10FS3-1-1, complete sequence	301179-301210	8	0.75
NZ_CP025753_9	9.22\|3083520\|32\|NZ_CP025753\|PILER-CR,CRT	3083520-3083551	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	148991-149022	8	0.75
NZ_CP025753_9	9.22\|3083520\|32\|NZ_CP025753\|PILER-CR,CRT	3083520-3083551	32	NC_007336	Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence	530640-530671	8	0.75
NZ_CP025753_9	9.23\|3083581\|32\|NZ_CP025753\|PILER-CR,CRT	3083581-3083612	32	NZ_CP006991	Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence	532343-532374	8	0.75
NZ_CP025753_9	9.25\|3083703\|32\|NZ_CP025753\|PILER-CR,CRT	3083703-3083734	32	MK448454	Streptococcus satellite phage Javan361, complete genome	9192-9223	8	0.75
NZ_CP025753_9	9.27\|3083825\|32\|NZ_CP025753\|CRT	3083825-3083856	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1428097-1428128	8	0.75
NZ_CP025753_6	6.1\|2581091\|42\|NZ_CP025753\|CRISPRCasFinder	2581091-2581132	42	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	24786-24827	9	0.786
NZ_CP025753_9	9.1\|3083032\|31\|NZ_CP025753\|CRISPRCasFinder	3083032-3083062	31	NC_011987	Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence	86182-86212	9	0.71
NZ_CP025753_9	9.2\|3083093\|31\|NZ_CP025753\|CRISPRCasFinder	3083093-3083123	31	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	244686-244716	9	0.71
NZ_CP025753_9	9.2\|3083093\|31\|NZ_CP025753\|CRISPRCasFinder	3083093-3083123	31	GU075905	Prochlorococcus phage P-HM2, complete genome	78536-78566	9	0.71
NZ_CP025753_9	9.4\|3083215\|31\|NZ_CP025753\|CRISPRCasFinder	3083215-3083245	31	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	405875-405905	9	0.71
NZ_CP025753_9	9.4\|3083215\|31\|NZ_CP025753\|CRISPRCasFinder	3083215-3083245	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2248363-2248393	9	0.71
NZ_CP025753_9	9.10\|3083581\|31\|NZ_CP025753\|CRISPRCasFinder	3083581-3083611	31	NZ_CP040723	Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence	35740-35770	9	0.71
NZ_CP025753_9	9.17\|3083215\|32\|NZ_CP025753\|PILER-CR,CRT	3083215-3083246	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	405875-405906	9	0.719
NZ_CP025753_9	9.22\|3083520\|32\|NZ_CP025753\|PILER-CR,CRT	3083520-3083551	32	NZ_CP036297	Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence	14953-14984	9	0.719
NZ_CP025753_9	9.22\|3083520\|32\|NZ_CP025753\|PILER-CR,CRT	3083520-3083551	32	NZ_CP036288	Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence	14983-15014	9	0.719
NZ_CP025753_9	9.22\|3083520\|32\|NZ_CP025753\|PILER-CR,CRT	3083520-3083551	32	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	3454-3485	9	0.719
NZ_CP025753_9	9.23\|3083581\|32\|NZ_CP025753\|PILER-CR,CRT	3083581-3083612	32	NZ_CP040723	Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence	35740-35771	9	0.719
NZ_CP025753_9	9.27\|3083825\|32\|NZ_CP025753\|CRT	3083825-3083856	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	141278-141309	9	0.719
NZ_CP025753_10	10.1\|3610698\|34\|NZ_CP025753\|CRISPRCasFinder	3610698-3610731	34	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15030-15063	9	0.735
NZ_CP025753_8	8.1\|3055529\|32\|NZ_CP025753\|PILER-CR,CRISPRCasFinder,CRT	3055529-3055560	32	NZ_CP030933	Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence	51062-51093	10	0.688
NZ_CP025753_9	9.14\|3083032\|32\|NZ_CP025753\|PILER-CR,CRT	3083032-3083063	32	NC_011987	Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence	86181-86212	10	0.688
NZ_CP025753_9	9.15\|3083093\|32\|NZ_CP025753\|PILER-CR,CRT	3083093-3083124	32	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	244686-244717	10	0.688
NZ_CP025753_9	9.15\|3083093\|32\|NZ_CP025753\|PILER-CR,CRT	3083093-3083124	32	GU075905	Prochlorococcus phage P-HM2, complete genome	78536-78567	10	0.688
NZ_CP025753_9	9.17\|3083215\|32\|NZ_CP025753\|PILER-CR,CRT	3083215-3083246	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2248362-2248393	10	0.688
NZ_CP025753_10	10.1\|3610698\|34\|NZ_CP025753\|CRISPRCasFinder	3610698-3610731	34	NZ_CP010859	Marinovum algicola DG 898 plasmid pMaD4, complete sequence	3636-3669	10	0.706

1. spacer 1.1|145810|40|NZ_CP025753|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 5.1|1141837|42|NZ_CP025753|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 0, identity: 1.0

tgtcacacgcagataaatccaactttcaatattgttaagttc	CRISPR spacer
tgtcacacgcagataaatccaactttcaatattgttaagttc	Protospacer
******************************************

3. spacer 5.2|1141896|40|NZ_CP025753|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 1, identity: 0.975

catggcgtagcaaaaagaaattttcaatattgctttatgg	CRISPR spacer
catggcgtagaaaaaagaaattttcaatattgctttatgg	Protospacer
********** *****************************

4. spacer 3.1|908976|48|NZ_CP025753|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

5. spacer 3.1|908976|48|NZ_CP025753|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

6. spacer 3.1|908976|48|NZ_CP025753|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

7. spacer 3.1|908976|48|NZ_CP025753|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 3, identity: 0.938

tcagcgtcgcatcaggcatctgcgcataaccgccggatgcggcgtaaa	CRISPR spacer
ccagcgtcgcatcaggcatctgcgcataactgccggatgcggcataaa	Protospacer
.*****************************.************.****

8. spacer 9.27|3083825|32|NZ_CP025753|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 3, identity: 0.906

ggcgcactggatgcgatgatggatatcactta	CRISPR spacer
gacgcactggatgcgatgatggacatcacttg	Protospacer
*.*********************.*******.

9. spacer 6.1|2581091|42|NZ_CP025753|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.833

acagcagtcggatgcggcgtaaacaccttatctgacctacgt	CRISPR spacer
acaaatgccggatgcggcgtaaacgccttatctggcctacgc	Protospacer
***.  *.****************.*********.******.

10. spacer 9.1|3083032|31|NZ_CP025753|CRISPRCasFinder matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
tccctatcgcaatgccggcagcatccgcaat	Protospacer
*. *.  ****** **** ************

11. spacer 9.1|3083032|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.774

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatc	Protospacer
**** ************ ***** *  ** .

12. spacer 9.1|3083032|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.774

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatc	Protospacer
**** ************ ***** *  ** .

13. spacer 9.4|3083215|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
agcgtcaccgacgcgcagggccgctaccaac	Protospacer
  **************** * *******.

14. spacer 9.9|3083520|31|NZ_CP025753|CRISPRCasFinder matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
ccgaacaggtggcgaagcaggtgatgggcca	Protospacer
******.* **************.. ***

15. spacer 9.27|3083825|32|NZ_CP025753|CRT matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 7, identity: 0.781

ggcgcactggatgcgatgatggat-atcactta	CRISPR spacer
ggcgcactggctgcgatgaaggacgatcaacc-	Protospacer
********** ******** ***. **** ..

16. spacer 6.1|2581091|42|NZ_CP025753|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 8, identity: 0.81

acagcagtcggatgcggcgtaaacaccttatctgacctacgt	CRISPR spacer
attgatgtcggatgcggcgtaaacgccttatccgacctacaa	Protospacer
*. *  ******************.*******.*******.

17. spacer 8.6|3055834|32|NZ_CP025753|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

tcaacgcgctcagacgttgcgtgagtgaacca	CRISPR spacer
acaacgcggtcggacgttgcgtgattaccccg	Protospacer
 ******* **.************ *.  **.

18. spacer 9.4|3083215|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP017753 (Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
gacgtcaccgacgcgcagtcgcgcttcttca	Protospacer
  ***************** ***** *. ..

19. spacer 9.7|3083398|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP044456 (Acinetobacter indicus strain B18 plasmid pB18-1, complete sequence) position: , mismatch: 8, identity: 0.742

ctaacgccacattggcggaattggctgctga	CRISPR spacer
ttgacgcgacattggctgaattggcttacta	Protospacer
.*.**** ******** *********  . *

20. spacer 9.7|3083398|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP039144 (Acinetobacter sp. 10FS3-1 plasmid p10FS3-1-1, complete sequence) position: , mismatch: 8, identity: 0.742

ctaacgccacattggcggaattggctgctga	CRISPR spacer
ttgacgcgacattggctgaattggcttacta	Protospacer
.*.**** ******** *********  . *

21. spacer 9.9|3083520|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP036297 (Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgt	Protospacer
   ..*.******** ********** ****

22. spacer 9.9|3083520|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP036288 (Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgt	Protospacer
   ..*.******** ********** ****

23. spacer 9.9|3083520|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
ttgcgcagctggcgcagcaggtggctgccga	Protospacer
..* .*.******* ************ **

24. spacer 9.9|3083520|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

ccgaacggctggcgaagcaggtggctggcgt	CRISPR spacer
gggtacggctggcgaaggaggcggctgcgga	Protospacer
  * ************* ***.*****  *

25. spacer 9.14|3083032|32|NZ_CP025753|PILER-CR,CRT matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
tccctatcgcaatgccggcagcatccgcaatc	Protospacer
*. *.  ****** **** ************.

26. spacer 9.14|3083032|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatca	Protospacer
**** ************ ***** *  ** .

27. spacer 9.14|3083032|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
ttgcgcgcgcaattccgtgagcagcgccatca	Protospacer
**** ************ ***** *  ** .

28. spacer 9.14|3083032|32|NZ_CP025753|PILER-CR,CRT matches to NC_008759 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcccgcg-----caattccgggagcatccgcaatt	CRISPR spacer
-----cgtgaaactcatttccgggagcatccgcattt	Protospacer
     **.*     ** ***************** **

29. spacer 9.17|3083215|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
agcgtcaccgacgcgcagggccgctaccaact	Protospacer
  **************** * *******.

30. spacer 9.17|3083215|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP017753 (Cupriavidus sp. USMAHM13 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
gacgtcaccgacgcgcagtcgcgcttcttcaa	Protospacer
  ***************** ***** *. ..*

31. spacer 9.20|3083398|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP044456 (Acinetobacter indicus strain B18 plasmid pB18-1, complete sequence) position: , mismatch: 8, identity: 0.75

ctaacgccacattggcggaattggctgctgat	CRISPR spacer
ttgacgcgacattggctgaattggcttactat	Protospacer
.*.**** ******** *********  . **

32. spacer 9.20|3083398|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP039144 (Acinetobacter sp. 10FS3-1 plasmid p10FS3-1-1, complete sequence) position: , mismatch: 8, identity: 0.75

ctaacgccacattggcggaattggctgctgat	CRISPR spacer
ttgacgcgacattggctgaattggcttactat	Protospacer
.*.**** ******** *********  . **

33. spacer 9.22|3083520|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
gggtacggctggcgaaggaggcggctgcggaa	Protospacer
  * ************* ***.*****  * *

34. spacer 9.22|3083520|32|NZ_CP025753|PILER-CR,CRT matches to NC_007336 (Cupriavidus pinatubonensis JMP134 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
ccgaacaggtggcgaagcaggtgatgggccag	Protospacer
******.* **************.. ***  .

35. spacer 9.23|3083581|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP006991 (Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence) position: , mismatch: 8, identity: 0.75

gtttaccgccccgcagaggcgctggcagatcc	CRISPR spacer
catcatcctcccgcagatgcgctggccgatcc	Protospacer
  *.*.* .******** ******** *****

36. spacer 9.25|3083703|32|NZ_CP025753|PILER-CR,CRT matches to MK448454 (Streptococcus satellite phage Javan361, complete genome) position: , mismatch: 8, identity: 0.75

tccgtttggtccaccaaatgtttgatgcttca	CRISPR spacer
tcttatcaatccaccaaatttttgattcttca	Protospacer
**.  *...********** ****** *****

37. spacer 9.27|3083825|32|NZ_CP025753|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

ggcgcactggatgcgatgatggata---tcactta	CRISPR spacer
ggcgcactggaagcggtgatggaggggcgcac---	Protospacer
*********** ***.******* .    ***

38. spacer 6.1|2581091|42|NZ_CP025753|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 9, identity: 0.786

acagcagtcggatgcggcgtaaacaccttatctgacctacgt	CRISPR spacer
gttgatgtcggatgcggcgtaaacgccttatccgacctacaa	Protospacer
.. *  ******************.*******.*******.

39. spacer 9.1|3083032|31|NZ_CP025753|CRISPRCasFinder matches to NC_011987 (Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence) position: , mismatch: 9, identity: 0.71

ttgcccgcgcaattccgggagcatccgcaat	CRISPR spacer
gctaccgcgcaattcgaggagcatccgctgg	Protospacer
 .  *********** .*********** .

40. spacer 9.2|3083093|31|NZ_CP025753|CRISPRCasFinder matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

acggacaaaatatatattgatttgcgaatta	CRISPR spacer
tgaggcaaaatatagattgatttccgaaaat	Protospacer
  .*.********* ******** ****

41. spacer 9.2|3083093|31|NZ_CP025753|CRISPRCasFinder matches to GU075905 (Prochlorococcus phage P-HM2, complete genome) position: , mismatch: 9, identity: 0.71

acggacaaaatatatattgatttgcgaatta	CRISPR spacer
acggaaaaattatatattgattttacttctg	Protospacer
***** *** *************     .*.

42. spacer 9.4|3083215|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
gacgtcactgacgcgcagtcgcgcttcttca	Protospacer
  ******.********** ***** *. ..

43. spacer 9.4|3083215|31|NZ_CP025753|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.71

cccgtcaccgacgcgcagtggcgctaccgtg	CRISPR spacer
gacatcaccgacgcccagtggcgcgacgtcc	Protospacer
  *.********** ********* **  .

44. spacer 9.10|3083581|31|NZ_CP025753|CRISPRCasFinder matches to NZ_CP040723 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.71

gtttaccgccccgcagaggcgctggcagatc	CRISPR spacer
cgagaccgcctcgccgaggcgctggcagcga	Protospacer
    ******.*** *************

45. spacer 9.17|3083215|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
gacgtcactgacgcgcagtcgcgcttcttcaa	Protospacer
  ******.********** ***** *. ..*

46. spacer 9.22|3083520|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP036297 (Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence) position: , mismatch: 9, identity: 0.719

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgtg	Protospacer
   ..*.******** ********** ****.

47. spacer 9.22|3083520|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP036288 (Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence) position: , mismatch: 9, identity: 0.719

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
agcggcagctggcgatgcaggtggcttgcgtg	Protospacer
   ..*.******** ********** ****.

48. spacer 9.22|3083520|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 9, identity: 0.719

ccgaacggctggcgaagcaggtggctggcgta	CRISPR spacer
ttgcgcagctggcgcagcaggtggctgccgag	Protospacer
..* .*.******* ************ ** .

49. spacer 9.23|3083581|32|NZ_CP025753|PILER-CR,CRT matches to NZ_CP040723 (Rhodococcus pyridinivorans strain YF3 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

gtttaccgccccgcagaggcgctggcagatcc	CRISPR spacer
cgagaccgcctcgccgaggcgctggcagcgac	Protospacer
    ******.*** *************   *

50. spacer 9.27|3083825|32|NZ_CP025753|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgcactggatgcgatgatggatatcactta	CRISPR spacer
ggcgcactggaaccgatgatggatgcgatgag	Protospacer
***********  ***********.. *.  .

51. spacer 10.1|3610698|34|NZ_CP025753|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 9, identity: 0.735

tgcatccggcacccggagcctgatgcgacgctgg	CRISPR spacer
atcaacaattaccaggtgcctgatgcgacgctgg	Protospacer
  ** * . .*** ** *****************

52. spacer 8.1|3055529|32|NZ_CP025753|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030933 (Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence) position: , mismatch: 10, identity: 0.688

tccacgctgtaacggccatcattaagtttagt	CRISPR spacer
ccgctgctgtgacgcccatcattaagttactc	Protospacer
.*  .*****.*** *************   .

53. spacer 9.14|3083032|32|NZ_CP025753|PILER-CR,CRT matches to NC_011987 (Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence) position: , mismatch: 10, identity: 0.688

ttgcccgcgcaattccgggagcatccgcaatt	CRISPR spacer
gctaccgcgcaattcgaggagcatccgctggg	Protospacer
 .  *********** .*********** .

54. spacer 9.15|3083093|32|NZ_CP025753|PILER-CR,CRT matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

acggacaaaatatatattgatttgcgaattat	CRISPR spacer
tgaggcaaaatatagattgatttccgaaaata	Protospacer
  .*.********* ******** ****

55. spacer 9.15|3083093|32|NZ_CP025753|PILER-CR,CRT matches to GU075905 (Prochlorococcus phage P-HM2, complete genome) position: , mismatch: 10, identity: 0.688

acggacaaaatatatattgatttgcgaattat	CRISPR spacer
acggaaaaattatatattgattttacttctgg	Protospacer
***** *** *************     .*.

56. spacer 9.17|3083215|32|NZ_CP025753|PILER-CR,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

cccgtcaccgacgcgcagtggcgctaccgtga	CRISPR spacer
gacatcaccgacgcccagtggcgcgacgtccc	Protospacer
  *.********** ********* **  .

57. spacer 10.1|3610698|34|NZ_CP025753|CRISPRCasFinder matches to NZ_CP010859 (Marinovum algicola DG 898 plasmid pMaD4, complete sequence) position: , mismatch: 10, identity: 0.706

tgcatccggcacccggagcctgatgcgacgctgg	CRISPR spacer
tgtcgaaggcacccgcaccctgatgcgacgcgcc	Protospacer
**.    ******** * *************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2861 : 30239

Escherichia_phage(52.94%)

portal,lysis,capsid,head,holin,tail,protease,integrase,terminase

attL 12428:12443|attR 31935:31950

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063101268.1\|2861_3122_-	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	7.1e-41	98.8
WP_001312914.1\|3163_3550_-\|tail	tail assembly protein	A0A1B5FP91	Escherichia_phage	6.8e-64	100.0
WP_000097533.1\|3549_4254_-	hypothetical protein	A0A1B5FP82	Escherichia_phage	1.5e-117	96.2
WP_001209399.1\|4313_4658_-	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	4.2e-57	100.0
WP_001312916.1\|4654_5104_-	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	7.9e-64	80.5
WP_001147820.1\|5100_5439_-\|head	phage head closure protein	A0A1B5FP90	Escherichia_phage	1.6e-56	99.1
WP_000983037.1\|5447_5753_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B5FP86	Escherichia_phage	9.2e-40	100.0
WP_000601355.1\|5764_5953_-	hypothetical protein	A0A1B5FP98	Escherichia_phage	7.2e-27	100.0
WP_000257489.1\|6004_7210_-\|capsid	phage major capsid protein	U5P0G9	Shigella_phage	1.3e-222	99.0
WP_001193631.1\|7224_7875_-\|head,protease	HK97 family phage prohead protease	U5P4H2	Shigella_phage	2.5e-119	100.0
WP_000466247.1\|7852_9094_-\|portal	phage portal protein	U5P411	Shigella_phage	5.9e-242	99.5
WP_000478567.1\|9093_9276_-	hypothetical protein	A0A1B5FP99	Escherichia_phage	1.1e-24	96.7
WP_021562585.1\|9287_11045_-\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	0.0e+00	99.7
WP_021558836.1\|11044_11527_-\|terminase	phage terminase small subunit P27 family	A0A1B5FPA0	Escherichia_phage	3.5e-86	99.4
WP_032191482.1\|11675_12026_-	HNH endonuclease	A0A1B5FP94	Escherichia_phage	2.1e-64	97.4
WP_032191479.1\|12265_12643_-	M15 family metallopeptidase	Q9MBZ3	Enterobacteria_phage	9.6e-63	96.0
12428:12443	attL	NA	NA	NA	NA
WP_032191664.1\|12645_12921_-\|holin	phage holin family protein	Q9MBZ4	Enterobacteria_phage	5.5e-44	96.7
WP_032191478.1\|12910_13303_-\|holin	holin	Q9MBZ5	Enterobacteria_phage	5.9e-55	96.2
WP_032191476.1\|13391_13544_-	DUF3927 family protein	NA	NA	NA	NA
WP_021558737.1\|13540_13966_-	tellurite resistance TerB family protein	Q71TK7	Escherichia_phage	2.3e-60	87.2
WP_134876106.1\|14518_14773_+	hypothetical protein	NA	NA	NA	NA
WP_032084568.1\|15583_16273_-	antiterminator	I6PDF8	Cronobacter_phage	9.6e-61	51.1
WP_000140004.1\|16269_16635_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	3.2e-39	67.5
WP_032191473.1\|16635_17691_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	7.0e-87	47.6
WP_032191662.1\|17692_17965_-	hypothetical protein	A0A077KB22	Edwardsiella_phage	1.3e-05	37.5
WP_001260977.1\|18100_18358_+	type II toxin-antitoxin system ParD family antitoxin	A0A0N7C055	Escherichia_phage	1.5e-30	86.7
WP_000220600.1\|18363_18663_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2R2Z2Y1	Escherichia_phage	3.9e-51	99.0
WP_032191472.1\|19878_20235_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	3.0e-58	98.3
WP_032191471.1\|20292_20715_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	8.8e-65	90.6
WP_032191469.1\|20755_21826_-	phage replisome organizer	A0A088CD36	Shigella_phage	3.2e-63	65.2
WP_000693850.1\|21897_22323_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_032191468.1\|22319_22535_-	transcriptional regulator	NA	NA	NA	NA
WP_000103684.1\|22584_23301_+	helix-turn-helix domain-containing protein	H9C160	Pectobacterium_phage	5.9e-53	42.4
WP_000379575.1\|23573_23729_+	DUF1391 family protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_001171942.1\|23888_24107_+	hypothetical protein	NA	NA	NA	NA
WP_000394519.1\|24129_24537_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	1.0e-09	40.9
WP_000920491.1\|24514_24748_-	hypothetical protein	NA	NA	NA	NA
WP_001605305.1\|24741_24909_-	hypothetical protein	NA	NA	NA	NA
WP_000854559.1\|25308_25497_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001083273.1\|25493_25685_+\|lysis	lysis protein YdfD	NA	NA	NA	NA
WP_032191466.1\|25778_28250_+	exonuclease	K7PLW7	Enterobacteria_phage	3.8e-59	60.9
WP_000003742.1\|28311_28581_+	excisionase	NA	NA	NA	NA
WP_032166781.1\|28549_29668_+\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	7.7e-84	44.2
WP_001113313.1\|29771_30239_-	DUF2335 domain-containing protein	A0A1B0YZW3	Pseudomonas_phage	2.4e-07	29.5
31935:31950	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1292280 : 1329328

Stx2-converting_phage(35.71%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085949199.1\|1292280_1293554_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	6.6e-172	96.0
WP_001424073.1\|1294168_1295782_-\|transposase	IS66-like element ISEc43 family transposase	A0A0P0ZEB3	Stx2-converting_phage	5.4e-171	61.2
WP_000624688.1\|1295812_1296163_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	6.2e-40	63.8
WP_001309734.1\|1296159_1296594_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-19	60.3
WP_000221545.1\|1297373_1297943_+	inovirus Gp2 family protein	NA	NA	NA	NA
WP_000270962.1\|1298202_1298604_+	hypothetical protein	NA	NA	NA	NA
WP_001221615.1\|1298591_1299026_+	hypothetical protein	NA	NA	NA	NA
WP_001171523.1\|1299380_1299761_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_000612633.1\|1299757_1301290_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.2e-239	81.4
WP_000823243.1\|1301528_1302887_-	esterase-like activity of phytase family protein	NA	NA	NA	NA
WP_000937736.1\|1303265_1303457_+	hypothetical protein	A0A0N7BTS3	Escherichia_phage	2.4e-06	96.2
WP_000555341.1\|1303619_1303877_-	hypothetical protein	NA	NA	NA	NA
WP_001283626.1\|1305627_1306149_+	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_001068910.1\|1306145_1307099_+	fec operon regulator FecR	NA	NA	NA	NA
WP_000188280.1\|1307185_1309510_+	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_000879152.1\|1309554_1310457_+	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_000125187.1\|1310453_1311452_+	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_000684856.1\|1311448_1312405_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
WP_000175457.1\|1312405_1313173_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
WP_000177059.1\|1313730_1313988_-	hypothetical protein	NA	NA	NA	NA
WP_001424070.1\|1315473_1316295_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_014639406.1\|1316297_1317386_+	putative hexosyltransferase CapU	NA	NA	NA	NA
WP_001424779.1\|1318405_1319350_+	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_000088350.1\|1319530_1320670_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.7e-68	45.1
WP_001293435.1\|1320823_1322821_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	7.4e-21	25.9
WP_001409274.1\|1322883_1324254_+	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_000145479.1\|1324407_1324626_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_001300609.1\|1324676_1325459_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.0e-139	100.0
WP_001424065.1\|1325455_1326478_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	7.8e-200	99.4
WP_000251886.1\|1326649_1327024_+	transcriptional regulator	NA	NA	NA	NA
WP_001422798.1\|1327204_1327333_-	alcohol dehydrogenase	NA	NA	NA	NA
WP_000080195.1\|1327714_1329328_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6

DBSCAN-SWA_3

2057134 : 2064410

Sodalis_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042634289.1\|2057134_2058454_-	hypothetical protein	B6SCW4	Bacteriophage	1.2e-35	43.2
WP_000909176.1\|2058453_2059131_-	hypothetical protein	Q2A0B2	Sodalis_phage	7.0e-56	71.6
WP_042634290.1\|2059124_2059586_-	DUF2824 family protein	Q2A0B3	Sodalis_phage	2.9e-61	71.5
WP_042634291.1\|2060348_2063105_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	1.5e-298	57.1
WP_001208878.1\|2063091_2063463_-	hypothetical protein	NA	NA	NA	NA
WP_000628966.1\|2063455_2063797_-	hypothetical protein	A0A1B5FPL8	Escherichia_phage	2.5e-33	61.5
WP_001058743.1\|2063807_2064410_-	hypothetical protein	A0A286S1S7	Klebsiella_phage	2.0e-25	36.3

DBSCAN-SWA_4

3097291 : 3104431

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001278994.1\|3097291_3097930_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590392.1\|3097926_3099189_-	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_000847985.1\|3099185_3100094_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_001297141.1\|3100289_3101057_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_001141340.1\|3101107_3101764_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	8.0e-49	46.3
WP_001272924.1\|3101869_3104431_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6

DBSCAN-SWA_5

3141328 : 3256823

114

Salmonella_phage(68.52%)

portal,lysis,capsid,plate,head,tail,integrase,tRNA,terminase

attL 3183866:3183903|attR 3218466:3218503

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000047176.1\|3141328_3143959_+\|tRNA	alanine--tRNA ligase	A0A2K9L1X7	Tupanvirus	5.5e-80	38.6
WP_000906486.1\|3144193_3144379_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	4.9e-12	66.7
WP_042634227.1\|3145561_3146128_+	fructose-1-phosphate/6-phosphogluconate phosphatase	NA	NA	NA	NA
WP_001287457.1\|3146124_3146553_+	DedA family protein	NA	NA	NA	NA
WP_000611802.1\|3146625_3148182_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_001130207.1\|3148331_3148847_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_001295176.1\|3148910_3150449_-	multidrug efflux MFS transporter permease subunit EmrB	NA	NA	NA	NA
WP_001295175.1\|3150465_3151638_-	multidrug efflux MFS transporter periplasmic adaptor subunit EmrA	NA	NA	NA	NA
WP_000378442.1\|3151764_3152295_-	multidrug efflux transporter EmrAB transcriptional repressor EmrR	NA	NA	NA	NA
WP_000119750.1\|3152385_3152721_-	L-valine transporter subunit YgaH	NA	NA	NA	NA
WP_000445658.1\|3152710_3153448_-	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_000165699.1\|3153571_3154756_-	MFS transporter	NA	NA	NA	NA
WP_001216521.1\|3155047_3156040_-	glycine betaine/L-proline ABC transporter substrate-binding protein ProX	NA	NA	NA	NA
WP_000774978.1\|3156097_3157162_-	glycine betaine/L-proline ABC transporter permease ProW	NA	NA	NA	NA
WP_000985494.1\|3157154_3158357_-	glycine betaine/L-proline ABC transporter ATP-binding protein ProV	G3M9Y6	Bacillus_virus	4.9e-28	39.4
WP_042634226.1\|3158711_3159671_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	4.5e-133	71.8
WP_000246537.1\|3159680_3161825_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	6.4e-196	48.5
WP_000080944.1\|3161797_3162208_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	2.7e-18	44.4
WP_001223227.1\|3162204_3162450_-	glutaredoxin-like protein NrdH	Q5K5J3	Oenococcus_phage	1.8e-06	35.3
WP_001295174.1\|3162697_3163027_-	DUF883 domain-containing protein	NA	NA	NA	NA
WP_000281320.1\|3163178_3163523_+	YgaC family protein	NA	NA	NA	NA
WP_000492656.1\|3163559_3164009_-	L-alanine exporter AlaE	NA	NA	NA	NA
WP_000115383.1\|3164676_3165081_+	DNA-binding protein StpA	NA	NA	NA	NA
WP_001229444.1\|3165127_3165652_-	thiosulfate sulfurtransferase YgaP	NA	NA	NA	NA
WP_000137280.1\|3165661_3165961_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000508177.1\|3166143_3166302_+	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_000522415.1\|3166385_3166835_+	potassium binding protein Kbp	A0A090DBR9	Clostridium_phage	2.0e-06	39.5
WP_000156811.1\|3166835_3167498_-	DNA-binding transcriptional regulator CsiR	NA	NA	NA	NA
WP_001295173.1\|3167518_3168919_-	GABA permease	NA	NA	NA	NA
WP_000097660.1\|3169156_3170437_-	4-aminobutyrate--2-oxoglutarate transaminase	A0A1V0SKB7	Klosneuvirus	1.4e-33	30.1
WP_000772854.1\|3170450_3171899_-	NADP-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000271984.1\|3171921_3173190_-	L-2-hydroxyglutarate oxidase	NA	NA	NA	NA
WP_001315804.1\|3173209_3174187_-	carbon starvation induced protein CsiD	NA	NA	NA	NA
WP_000961357.1\|3178161_3179535_+	DUF5507 domain-containing protein	NA	NA	NA	NA
WP_072161517.1\|3179920_3180109_+	DNA invertase	A0A1S6L009	Salmonella_phage	9.1e-06	69.2
WP_000927517.1\|3180263_3180383_+	hypothetical protein	NA	NA	NA	NA
3183866:3183903	attL	NA	NA	NA	NA
WP_000660070.1\|3184098_3185832_+	deoxycytidylate deaminase	NA	NA	NA	NA
WP_000218398.1\|3186211_3187228_-\|integrase	site-specific integrase	E5G6L0	Salmonella_phage	6.1e-189	93.5
WP_000932270.1\|3187230_3187863_-	phage repressor protein CI	A0A1S6KZZ7	Salmonella_phage	1.1e-58	51.9
WP_000102105.1\|3187984_3188227_+	Rha family transcriptional regulator	A0A1S6KZZ6	Salmonella_phage	6.8e-38	97.5
WP_000460865.1\|3188259_3188769_+	phage regulatory CII family protein	E5G6L3	Salmonella_phage	6.6e-83	94.7
WP_000956186.1\|3188776_3189073_+	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	1.1e-21	93.9
WP_000996711.1\|3189190_3189532_+	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	1.9e-54	96.5
WP_001244211.1\|3189599_3189833_+	DUF2732 family protein	E5G6L6	Salmonella_phage	4.6e-31	94.8
WP_000752613.1\|3189832_3190060_+	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	2.7e-36	100.0
WP_000104161.1\|3190056_3190914_+	DNA adenine methylase	E5G6L8	Salmonella_phage	1.8e-157	94.7
WP_000017515.1\|3190910_3193325_+	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	97.9
WP_001154434.1\|3193478_3193667_+	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_001217575.1\|3193677_3193911_+	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_032235580.1\|3194281_3194977_+	hypothetical protein	NA	NA	NA	NA
WP_001384725.1\|3195376_3195634_+	hypothetical protein	NA	NA	NA	NA
WP_001384724.1\|3195750_3196155_+	hypothetical protein	NA	NA	NA	NA
WP_000520371.1\|3196185_3197211_-\|portal	phage portal protein	E5G6M3	Salmonella_phage	6.9e-172	88.5
WP_001098447.1\|3197210_3198977_-\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.3
WP_000216261.1\|3199119_3199953_+\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	1.5e-121	91.7
WP_000742510.1\|3199969_3201028_+\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	3.8e-181	93.4
WP_000059211.1\|3201031_3201682_+\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	1.9e-111	95.8
WP_000673529.1\|3201777_3202242_+\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	8.4e-77	89.6
WP_000868175.1\|3202241_3202445_+\|tail	tail protein X	E5G6M9	Salmonella_phage	1.4e-31	92.5
WP_000171568.1\|3202448_3202664_+	hypothetical protein	E5G6N0	Salmonella_phage	1.8e-26	80.3
WP_085959187.1\|3202683_3203157_+	lysozyme	E5G6N1	Salmonella_phage	3.7e-80	91.0
WP_000730950.1\|3203158_3203536_+	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	1.1e-15	39.2
WP_001384723.1\|3203532_3203961_+\|lysis	LysB family phage lysis regulatory protein	E5G6N2	Salmonella_phage	3.8e-47	77.3
WP_001039945.1\|3204056_3204488_+\|tail	phage tail protein	E5G6N3	Salmonella_phage	4.4e-72	94.4
WP_000829119.1\|3204480_3204927_+	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	2.3e-63	86.3
WP_000993744.1\|3204995_3205574_+\|plate	phage baseplate assembly protein V	A0A1S6KZX7	Salmonella_phage	9.4e-94	86.5
WP_000177580.1\|3205570_3205930_+\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	3.2e-52	87.4
WP_000268289.1\|3205916_3206825_+\|plate	baseplate assembly protein	A0A1S6KZY6	Salmonella_phage	2.7e-143	90.4
WP_001086842.1\|3206817_3207423_+\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	7.5e-110	92.0
WP_000104774.1\|3207419_3209507_+\|tail	tail fiber protein	A0A0F7LDR4	Escherichia_phage	3.6e-74	42.7
WP_001098219.1\|3209506_3209920_+\|tail	tail fiber assembly protein	U5P0S4	Shigella_phage	5.8e-21	73.0
WP_000046128.1\|3210026_3211199_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.0e-203	90.3
WP_001207660.1\|3211208_3211724_+\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	2.1e-89	95.3
WP_001281009.1\|3211778_3212081_+\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	5.3e-40	89.0
WP_000763311.1\|3212095_3212215_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.8e-13	87.2
WP_001282739.1\|3212207_3215285_+\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	69.3
WP_000980384.1\|3215281_3215767_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	1.8e-66	80.6
WP_001011766.1\|3215763_3216864_+	phage late control D family protein	E5G6Q3	Salmonella_phage	3.4e-177	85.5
WP_000972389.1\|3216954_3217173_+	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	1.9e-18	71.9
WP_000151541.1\|3217576_3218350_+	reverse transcriptase	NA	NA	NA	NA
WP_000162574.1\|3219035_3219518_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
3218466:3218503	attR	NA	NA	NA	NA
WP_000600189.1\|3219649_3220126_+	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_001117846.1\|3220115_3220406_+	RnfH family protein	NA	NA	NA	NA
WP_001203437.1\|3220467_3220809_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_000880910.1\|3220957_3222619_-	DNA repair protein RecN	NA	NA	NA	NA
WP_001059169.1\|3222704_3223583_-	NAD(+) kinase	NA	NA	NA	NA
WP_001296310.1\|3223705_3224299_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_010723175.1\|3224353_3225640_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001338897.1\|3225660_3226452_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_000460035.1\|3226618_3227980_+	signal recognition particle protein	NA	NA	NA	NA
WP_000256450.1\|3228116_3228365_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_000043335.1\|3228383_3228932_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000264777.1\|3228962_3229730_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000065253.1\|3229771_3230119_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_000589828.1\|3230194_3230677_-	OmpA family protein	NA	NA	NA	NA
WP_000969010.1\|3230692_3231919_-	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_001212391.1\|3231908_3232427_-	YfiR family protein	NA	NA	NA	NA
WP_000976004.1\|3232576_3232942_-	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_001168045.1\|3233151_3234222_+	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	4.0e-90	51.2
WP_000225221.1\|3234232_3235354_+	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_000200101.1\|3235396_3236557_-	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_001700969.1\|3236655_3236703_-	hypothetical protein	NA	NA	NA	NA
WP_000178456.1\|3236806_3237148_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_000197686.1\|3237418_3238156_-	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000079100.1\|3238290_3239271_+	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000040129.1\|3239267_3239999_+	polyphenol oxidase	NA	NA	NA	NA
WP_001235102.1\|3240128_3242702_+	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000841103.1\|3248567_3249866_+	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	1.3e-45	32.2
WP_001300818.1\|3249862_3250186_-	YfiM family lipoprotein	NA	NA	NA	NA
WP_000949265.1\|3250231_3251587_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_000082969.1\|3251700_3254361_-	protein lysine acetyltransferase	NA	NA	NA	NA
WP_000138184.1\|3254392_3255091_-	DTW domain-containing protein	NA	NA	NA	NA
WP_001098726.1\|3255159_3255579_-	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_000997403.1\|3255785_3256823_+\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA

DBSCAN-SWA_6

3747169 : 3756610

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569358.1\|3747169_3748096_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	1.7e-23	30.8
WP_000783120.1\|3748100_3748832_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|3748812_3748920_-	protein YohO	NA	NA	NA	NA
WP_001240401.1\|3748979_3749711_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|3749932_3751618_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|3751614_3752334_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000950409.1\|3752380_3752851_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	5.2e-82	100.0
WP_001295429.1\|3752890_3753352_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_103042683.1\|3753476_3755477_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.0
WP_001292774.1\|3755473_3756610_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7

DBSCAN-SWA_7

3849418 : 3856957

Enterobacteria_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001116049.1\|3849418_3850813_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	2.8e-19	31.9
WP_000999466.1\|3850970_3851966_+	SDR family oxidoreductase	A0A1V0QG29	Shearwaterpox_virus	1.9e-09	26.3
WP_000183060.1\|3852208_3853102_+	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_000699430.1\|3853474_3854560_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.1e-100	53.9
WP_001023629.1\|3854559_3855462_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	4.4e-29	35.2
WP_000857541.1\|3855516_3856395_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	6.6e-107	64.1
WP_001100798.1\|3856399_3856957_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	3.9e-52	58.8

DBSCAN-SWA_8

3923196 : 4055034

132

Enterobacteria_phage(33.33%)

portal,lysis,capsid,head,holin,tail,transposase,protease,integrase,tRNA,terminase

attL 3923186:3923245|attR 4030331:4031661

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3923186:3923245	attL	NA	NA	NA	NA
WP_085949199.1\|3923196_3924470_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	6.6e-172	96.0
WP_001323489.1\|3926006_3926717_-	inverse autotransporter beta-barrel domain-containing protein	NA	NA	NA	NA
WP_000784549.1\|3927408_3929430_-	siderophore yersiniabactin receptor FyuA	NA	NA	NA	NA
WP_001088826.1\|3929560_3931138_-	yersiniabactin biosynthesis salycil-AMP ligase YbtE	NA	NA	NA	NA
WP_000194282.1\|3931141_3931945_-	yersiniabactin biosynthesis thioesterase YbtT	NA	NA	NA	NA
WP_000982866.1\|3931941_3933042_-	yersiniabactin biosynthesis oxidoreductase YbtU	NA	NA	NA	NA
WP_000369518.1\|3933038_3942530_-	yersiniabactin polyketide synthase HMWP1	D0R7J2	Paenibacillus_phage	1.6e-49	36.8
WP_000623064.1\|3942617_3948725_-	yersiniabactin non-ribosomal peptide synthetase HMWP2	A0A2K9L3I8	Tupanvirus	4.0e-33	27.3
WP_000970688.1\|3948915_3949875_-	yersiniabactin transcriptional regulator YbtA	NA	NA	NA	NA
WP_000098398.1\|3950041_3951844_+	yersiniabactin ABC transporter ATP-binding/permease protein YbtP	W8CYL7	Bacillus_phage	1.4e-31	27.6
WP_001334858.1\|3951830_3953633_+	yersiniabactin ABC transporter ATP-binding/permease protein YbtQ	W8CYL7	Bacillus_phage	6.1e-22	26.5
WP_001286287.1\|3953625_3954906_+	yersiniabactin-associated zinc MFS transporter YbtX	NA	NA	NA	NA
WP_000703039.1\|3954933_3956238_+	yersiniabactin biosynthesis salicylate synthase YbtS	NA	NA	NA	NA
WP_001300801.1\|3957684_3958482_-	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_000533615.1\|3958717_3959743_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	3.4e-102	57.9
WP_000096344.1\|3959742_3959946_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_103042684.1\|3960004_3962446_-	exonuclease	V5UQJ3	Shigella_phage	1.0e-112	47.0
WP_001070256.1\|3962539_3962731_-	DUF1482 family protein	NA	NA	NA	NA
WP_000854558.1\|3962727_3962916_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001296188.1\|3963315_3963480_+	hypothetical protein	NA	NA	NA	NA
WP_001171946.1\|3963483_3963702_-	hypothetical protein	NA	NA	NA	NA
WP_001384640.1\|3963861_3964017_-	DUF1391 family protein	M4QQ57	Salicola_phage	3.4e-06	48.9
WP_000233320.1\|3964314_3964734_-	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	4.2e-19	47.5
WP_001072337.1\|3964813_3965068_+	hypothetical protein	A0A2I6PIE5	Escherichia_phage	2.8e-18	60.3
WP_000693850.1\|3965064_3965490_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001262376.1\|3965561_3966638_+	hypothetical protein	A0A088CD36	Shigella_phage	1.5e-63	65.7
WP_001151223.1\|3966678_3967089_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.2e-63	91.2
WP_042634476.1\|3967158_3967515_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	6.7e-58	97.5
WP_000797277.1\|3967639_3967822_+	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	6.1e-23	92.6
WP_001384637.1\|3967818_3968010_+	hypothetical protein	A0A0F6R8N3	Escherichia_coli_O157_typing_phage	3.3e-27	93.7
WP_000951709.1\|3968011_3968227_+	hypothetical protein	A0A1I9LJM3	Stx_converting_phage	5.7e-36	97.2
WP_001142589.1\|3968228_3968447_+	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	5.2e-29	88.9
WP_000224213.1\|3968448_3968712_+	hypothetical protein	A0A2P0P958	Salmonella_phage	1.5e-30	71.3
WP_000206831.1\|3968722_3969067_+	hypothetical protein	A0A2R2Z2X8	Escherichia_phage	7.4e-54	92.1
WP_000673136.1\|3969266_3969557_+	hypothetical protein	NA	NA	NA	NA
WP_000018425.1\|3970696_3970909_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	2.0e-17	68.6
WP_000737636.1\|3971052_3971445_+	hypothetical protein	NA	NA	NA	NA
WP_032173433.1\|3971741_3972020_+	hypothetical protein	NA	NA	NA	NA
WP_015675170.1\|3972021_3973071_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	2.1e-107	54.0
WP_001217424.1\|3973083_3973443_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	8.3e-40	67.5
WP_001064900.1\|3973439_3974129_+	antiterminator	I6PDF8	Cronobacter_phage	5.8e-58	49.8
WP_001384627.1\|3975290_3975683_+\|holin	holin	Q9MBZ5	Enterobacteria_phage	3.4e-55	90.0
WP_000950569.1\|3975672_3975948_+\|holin	phage holin family protein	Q9MBZ4	Enterobacteria_phage	7.2e-44	96.7
WP_000014549.1\|3975950_3976328_+	M15 family metallopeptidase	Q9MBZ3	Enterobacteria_phage	1.3e-64	98.4
WP_134267542.1\|3976342_3976522_+	hypothetical protein	NA	NA	NA	NA
WP_042634360.1\|3976760_3976970_-	hypothetical protein	NA	NA	NA	NA
WP_001140107.1\|3977391_3977742_+	HNH endonuclease	A0A1B5FP94	Escherichia_phage	6.2e-64	97.4
WP_001317918.1\|3977890_3978373_+\|terminase	phage terminase small subunit P27 family	A0A1B5FPA0	Escherichia_phage	5.7e-84	97.5
WP_021562585.1\|3978372_3980130_+\|terminase	terminase large subunit	A0A1B5FP96	Escherichia_phage	0.0e+00	99.7
WP_000478567.1\|3980141_3980324_+	hypothetical protein	A0A1B5FP99	Escherichia_phage	1.1e-24	96.7
WP_000466247.1\|3980323_3981565_+\|portal	phage portal protein	U5P411	Shigella_phage	5.9e-242	99.5
WP_001193631.1\|3981542_3982193_+\|head,protease	HK97 family phage prohead protease	U5P4H2	Shigella_phage	2.5e-119	100.0
WP_000257489.1\|3982207_3983413_+\|capsid	phage major capsid protein	U5P0G9	Shigella_phage	1.3e-222	99.0
WP_032191505.1\|3983464_3983653_+	hypothetical protein	A0A1B5FP98	Escherichia_phage	2.7e-26	98.4
WP_001605322.1\|3983664_3983970_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B5FP86	Escherichia_phage	1.7e-38	80.2
WP_001605323.1\|3983978_3984317_+\|head	phage head closure protein	A0A1B5FP90	Escherichia_phage	3.5e-56	98.2
WP_032159263.1\|3984313_3984763_+	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	6.1e-64	81.2
WP_001605325.1\|3984759_3985104_+	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	1.2e-56	99.1
WP_001605326.1\|3985164_3985869_+	hypothetical protein	A0A1B5FP82	Escherichia_phage	2.8e-116	94.9
WP_001312914.1\|3985868_3986255_+\|tail	tail assembly protein	A0A1B5FP91	Escherichia_phage	6.8e-64	100.0
WP_077763502.1\|3986296_3986557_+	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	3.5e-40	97.7
WP_077763495.1\|3989802_3990159_+\|tail	phage tail protein	A0A0P0ZDL9	Stx2-converting_phage	5.3e-39	65.8
WP_032191512.1\|3990158_3990857_+\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	2.8e-132	97.8
WP_064752038.1\|3990861_3991605_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	8.6e-148	97.6
WP_042634545.1\|3991541_3992144_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.2e-88	85.6
WP_103042685.1\|3992204_3995684_+	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	89.4
WP_032191516.1\|3995751_3996351_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	3.5e-107	96.5
WP_000799406.1\|3999245_4000109_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000531601.1\|4000092_4001229_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	9.4e-29	39.8
WP_000359457.1\|4001478_4002705_+	peptidase T	NA	NA	NA	NA
WP_001295435.1\|4002753_4003875_-	cupin domain-containing protein	NA	NA	NA	NA
WP_000735412.1\|4003950_4005411_-	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_001265471.1\|4005410_4006082_-	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000423742.1\|4006250_4007621_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.2e-107	44.9
WP_001297479.1\|4007624_4008266_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_001297484.1\|4008301_4009408_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000476093.1\|4009461_4009923_-	phosphatase NudJ	NA	NA	NA	NA
WP_001248691.1\|4009932_4010586_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000444487.1\|4010757_4012008_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_000741338.1\|4012121_4013264_-\|integrase	tyrosine-type recombinase/integrase	O21929	Phage_21	6.2e-206	100.0
WP_000088653.1\|4013253_4013490_-	excisionase	NA	NA	NA	NA
WP_000488406.1\|4013629_4013869_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	3.9e-38	94.9
WP_000763387.1\|4013916_4014135_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	1.7e-35	98.6
WP_001386642.1\|4014233_4014515_-	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	5.5e-47	98.9
WP_000129285.1\|4014525_4015083_-	phage N-6-adenine-methyltransferase	E5AGF8	Erwinia_phage	2.0e-61	62.3
WP_000682314.1\|4015075_4015237_-	DUF1317 family protein	A0A0P0ZAS9	Stx2-converting_phage	1.2e-22	98.0
WP_000186763.1\|4015233_4015914_-	YqaJ viral recombinase family protein	A0A0N6WET1	Escherichia_phage	3.0e-131	99.6
WP_000100847.1\|4015910_4016696_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995419.1\|4016701_4016998_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	6.8e-48	98.0
WP_000233576.1\|4017074_4017281_-	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000581650.1\|4017759_4018272_-	DUF4411 family protein	NA	NA	NA	NA
WP_000741702.1\|4018268_4019408_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_001295669.1\|4019537_4020230_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.5e-109	86.1
WP_000184665.1\|4020340_4020568_+	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	3.8e-22	69.0
WP_001182885.1\|4020598_4021138_+	hypothetical protein	M9NZI6	Enterobacteria_phage	6.8e-62	66.7
WP_001384422.1\|4021224_4022154_+	replication protein	A0A0M5M7Y1	Salmonella_phage	3.6e-111	63.8
WP_000788783.1\|4022150_4022864_+	hypothetical protein	G8C7U6	Escherichia_phage	1.7e-108	83.4
WP_000608370.1\|4022942_4023371_-	hypothetical protein	NA	NA	NA	NA
WP_157905615.1\|4024372_4024522_-	hypothetical protein	NA	NA	NA	NA
WP_000174718.1\|4024786_4025242_+	hypothetical protein	I6PD71	Cronobacter_phage	2.7e-59	66.2
WP_000224916.1\|4025241_4025412_+	hypothetical protein	K7P7K0	Enterobacteria_phage	1.5e-12	67.9
WP_000774480.1\|4025404_4025695_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	3.0e-48	95.8
WP_001099700.1\|4025691_4026054_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	7.3e-60	96.5
WP_000971068.1\|4026050_4026191_+	YlcG family protein	K7PHH3	Enterobacteria_phage	5.5e-08	67.4
WP_001204791.1\|4026276_4026660_+	antitermination protein QuuD	A0A088CD47	Shigella_phage	4.4e-55	83.3
WP_000737275.1\|4026848_4027931_-	porin OmpD	Q1MVN1	Enterobacteria_phage	8.9e-154	76.3
WP_000839596.1\|4028504_4028720_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_001135275.1\|4028719_4029109_+	glycoside hydrolase family protein	A0A291AWW2	Escherichia_phage	1.2e-57	97.3
WP_085949199.1\|4029105_4030378_+\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	6.6e-172	96.0
WP_077628513.1\|4030769_4030952_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.5e-16	96.7
WP_000738423.1\|4031042_4031336_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
WP_001307652.1\|4031698_4031893_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
4030331:4031661	attR	NA	NA	NA	NA
WP_000453580.1\|4032281_4032827_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.8e-95	100.0
WP_001027268.1\|4032801_4034727_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.7
WP_000198149.1\|4034723_4034930_+\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001356819.1\|4034926_4036528_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.1e-309	99.2
WP_000123313.1\|4036508_4037828_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	4.5e-232	98.2
WP_001299443.1\|4037837_4038170_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.7e-55	100.0
WP_000063241.1\|4038225_4039251_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.7e-191	99.1
WP_000158875.1\|4039292_4039688_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	1.1e-58	95.5
WP_000753000.1\|4039699_4040053_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	1.2e-62	99.1
WP_000975068.1\|4040064_4040643_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	7.8e-80	99.0
WP_000683105.1\|4040639_4041035_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_001380324.1\|4041042_4041783_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	9.5e-131	98.4
WP_000479172.1\|4041798_4042221_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.8e-68	94.3
WP_000459457.1\|4042202_4042637_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000847350.1\|4045205_4045535_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	4.7e-58	98.2
WP_001152505.1\|4045534_4046233_+\|tail	phage minor tail protein L	A5LH40	Enterobacteria_phage	1.1e-128	96.1
WP_000140737.1\|4046237_4046981_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.9e-147	96.8
WP_000090892.1\|4046917_4047550_+\|tail	tail assembly protein	C6ZCZ4	Enterobacteria_phage	2.7e-94	98.1
WP_001233178.1\|4051094_4051694_+	Ail/Lom family outer membrane beta-barrel protein	K7PJP9	Enterobacteria_phage	6.7e-111	99.5
WP_000268788.1\|4051758_4055034_+\|tail	phage tail protein	K7PGT9	Enterobacteria_phage	1.3e-309	72.2

DBSCAN-SWA_9

4463123 : 4505491

Enterobacteria_phage(52.38%)

portal,lysis,tail,protease,transposase,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_122985608.1\|4463123_4463237_+	hypothetical protein	A0A1C9IHU6	Salmonella_phage	2.9e-07	83.3
WP_000836768.1\|4463305_4463539_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
WP_000086527.1\|4463856_4464447_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-24	38.8
WP_000885587.1\|4464544_4465120_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.0e-104	96.9
WP_024183964.1\|4465119_4468143_-\|tail	tail protein	U5N099	Enterobacteria_phage	2.1e-67	81.4
WP_001230352.1\|4468207_4468807_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	1.3e-109	97.5
WP_000515631.1\|4468873_4472272_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	88.6
WP_023277304.1\|4472332_4472980_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	4.7e-110	94.9
WP_000194816.1\|4472877_4473621_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	3.5e-149	97.6
WP_001152385.1\|4473626_4474325_-\|tail	phage minor tail protein L	A5LH40	Enterobacteria_phage	6.0e-135	100.0
WP_000447253.1\|4474334_4474664_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	1.7e-60	100.0
WP_000372058.1\|4474663_4477729_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	0.0e+00	99.1
WP_001161009.1\|4477700_4478030_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.6e-56	100.0
WP_001384509.1\|4478038_4478425_-\|tail	phage minor tail protein G	A0A291AWW5	Escherichia_phage	2.2e-62	96.9
WP_000211131.1\|4478485_4479229_-\|tail	phage tail protein	A0A291AWU6	Escherichia_phage	3.6e-130	97.6
WP_001079398.1\|4479239_4479641_-\|tail	tail protein	A0A291AWY2	Escherichia_phage	8.3e-73	100.0
WP_000677102.1\|4479637_4480216_-\|tail	phage tail protein	A5LH33	Enterobacteria_phage	1.2e-101	99.5
WP_001283152.1\|4480227_4480503_-	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	8.6e-45	98.9
WP_001097052.1\|4480495_4480819_-	DUF2190 family protein	K7PLV6	Enterobacteria_phage	9.4e-51	99.1
WP_001136599.1\|4480905_4482933_-\|protease	Clp protease ClpP	A5LH30	Enterobacteria_phage	0.0e+00	99.4
WP_077631397.1\|4482910_4484458_-\|portal	phage portal protein	K7PJP3	Enterobacteria_phage	8.5e-283	99.6
WP_001072975.1\|4484385_4484598_-	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_000507032.1\|4484594_4486694_-\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	0.0e+00	98.6
WP_000421825.1\|4486702_4487242_-	DUF1441 family protein	A5LH26	Enterobacteria_phage	1.8e-94	100.0
WP_001031431.1\|4487810_4488017_-	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	6.7e-26	91.2
WP_000035574.1\|4488317_4488728_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	2.1e-63	89.0
WP_001019606.1\|4488879_4489053_-	addiction module toxin, GnsA/GnsB family	NA	NA	NA	NA
WP_001309517.1\|4489224_4489380_-	hypothetical protein	NA	NA	NA	NA
WP_122134696.1\|4489459_4489525_-	hypothetical protein	NA	NA	NA	NA
WP_071524604.1\|4489527_4489716_-	cold-shock protein	NA	NA	NA	NA
WP_000066495.1\|4489726_4489939_-	cold shock protein CspI	A0A1W6JNX5	Morganella_phage	1.2e-22	74.3
WP_001071769.1\|4490302_4490800_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	2.9e-06	29.5
WP_001092971.1\|4490796_4491330_-	lysozyme	K7PLY1	Enterobacteria_phage	6.4e-97	93.2
WP_000189915.1\|4491326_4491638_-	YdfR family protein	K7PGU6	Enterobacteria_phage	2.0e-26	64.6
WP_000839590.1\|4491642_4491858_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	1.1e-31	94.4
WP_000066484.1\|4492611_4492827_-	cold shock-like protein CspB	A0A1W6JNX5	Morganella_phage	3.4e-25	76.5
WP_000087756.1\|4493127_4493340_+	cold shock-like protein CspF	NA	NA	NA	NA
WP_120795389.1\|4493394_4493484_+	Qin prophage; protein YnfS	NA	NA	NA	NA
WP_001047135.1\|4493761_4494514_-	antitermination protein	A0A192Y5X6	Salmonella_phage	7.1e-134	92.8
WP_001265198.1\|4494527_4495577_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.3e-112	57.3
WP_012304870.1\|4495578_4495857_-	hypothetical protein	NA	NA	NA	NA
WP_000980994.1\|4495923_4496175_-	hypothetical protein	NA	NA	NA	NA
WP_000813254.1\|4496391_4496547_-	type I toxin-antitoxin system toxin HokD	A0A0U2QV81	Escherichia_phage	1.5e-17	96.1
WP_000323025.1\|4496618_4496906_-	type II toxin-antitoxin system mRNA interferase RelE	A0A2H4JBF4	uncultured_Caudovirales_phage	1.4e-29	66.0
WP_000534858.1\|4496905_4497145_-	type II toxin-antitoxin system antitoxin RelB	A0A2H4JBG1	uncultured_Caudovirales_phage	1.6e-18	54.4
WP_001326990.1\|4497169_4497475_+	hypothetical protein	NA	NA	NA	NA
WP_001317460.1\|4497677_4498010_+	protein flxA	NA	NA	NA	NA
WP_000589012.1\|4498446_4499787_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_001151195.1\|4499820_4500240_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.3e-55	93.4
WP_000054506.1\|4500280_4501246_-	hypothetical protein	U5P0A0	Shigella_phage	1.7e-55	61.2
WP_000705349.1\|4501226_4501748_-	hypothetical protein	NA	NA	NA	NA
WP_000476993.1\|4501731_4501959_-	transcriptional regulator	NA	NA	NA	NA
WP_001003381.1\|4502036_4502444_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	2.5e-24	46.2
WP_000379589.1\|4502635_4502791_+	DUF1391 family protein	M4QQ57	Salicola_phage	8.8e-07	51.1
WP_000344954.1\|4502792_4503368_+	hypothetical protein	NA	NA	NA	NA
WP_000854559.1\|4503854_4504043_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_085949199.1\|4504217_4505491_-\|transposase	IS3 family transposase	Q9ZXG3	Shigella_phage	6.6e-172	96.0

DBSCAN-SWA_10

4915473 : 4930959

Escherichia_phage(50.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_074152286.1\|4915473_4915599_-\|tail	phage tail protein	K7PMH7	Enterobacteria_phage	2.3e-13	87.5
WP_000268786.1\|4915653_4918929_-	hypothetical protein	K7PGT9	Enterobacteria_phage	4.6e-302	71.0
WP_001230299.1\|4918993_4919593_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	4.8e-109	97.0
WP_000515626.1\|4919661_4923057_-	host specificity protein J	A0A0K2FI38	Escherichia_phage	0.0e+00	89.9
WP_012311734.1\|4923117_4923765_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.8e-110	96.3
WP_001423886.1\|4923662_4924406_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	6.4e-143	93.1
WP_001152456.1\|4924410_4925109_-\|tail	phage minor tail protein L	A0A1B5FP81	Escherichia_phage	4.4e-130	96.6
WP_040079256.1\|4925108_4925465_-\|tail	tail protein	A0A0P0ZDL9	Stx2-converting_phage	1.4e-39	65.8
WP_042634620.1\|4925442_4928670_-\|tail	phage tail tape measure protein	A0A1B5FPE2	Escherichia_phage	0.0e+00	95.7
WP_077763502.1\|4928715_4928976_-	DUF4035 domain-containing protein	A0A1B5FP87	Escherichia_phage	3.5e-40	97.7
WP_001312914.1\|4929017_4929404_-\|tail	tail assembly protein	A0A1B5FP91	Escherichia_phage	6.8e-64	100.0
WP_001605326.1\|4929403_4930108_-	hypothetical protein	A0A1B5FP82	Escherichia_phage	2.8e-116	94.9
WP_001605325.1\|4930168_4930513_-	DUF3168 domain-containing protein	A0A1B5FP84	Escherichia_phage	1.2e-56	99.1
WP_032159263.1\|4930509_4930959_-	HK97 gp10 family phage protein	S4TR46	Salmonella_phage	6.1e-64	81.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP025752

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1095 : 12260

Escherichia_phage(42.86%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_094392493.1\|1095_1329_-	hypothetical protein	A0A222YWI5	Escherichia_phage	2.0e-10	50.0
WP_000080195.1\|1457_3071_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000624722.1\|3101_3452_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|3448_3874_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_077632055.1\|5119_5902_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.2e-138	99.2
WP_000255956.1\|5898_6921_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-199	99.1
WP_001384779.1\|8168_12260_+	autotransporter outer membrane beta-barrel domain-containing protein	Q9LA58	Enterobacterial_phage	2.4e-284	42.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP025751

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

20064 : 60400

Sodalis_phage(12.5%)

integrase,transposase

attL 38854:38868|attR 53098:53112

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001352368.1\|20064_21273_+\|transposase	IS4-like element ISVsa5 family transposase	A0A0F7LAS3	uncultured_marine_virus	1.8e-235	100.0
WP_000599533.1\|21638_22844_-	sodium/glutamate symporter	NA	NA	NA	NA
WP_000562370.1\|23287_23608_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_000460651.1\|23600_23987_+	hypothetical protein	NA	NA	NA	NA
WP_001284954.1\|23994_24681_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001322387.1\|24658_25285_-	tetracycline resistance transcriptional repressor TetR(B)	NA	NA	NA	NA
WP_001089072.1\|25363_26569_+	tetracycline efflux MFS transporter Tet(B)	NA	NA	NA	NA
WP_000428546.1\|26681_27275_-	tetracyline resistance-associated transcriptional repressor TetC	NA	NA	NA	NA
WP_001339197.1\|27788_28997_-\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0
WP_085967404.1\|29066_30196_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	8.7e-51	40.1
WP_000904897.1\|30226_30850_-	recombinase family protein	E5FFF9	Burkholderia_phage	2.3e-37	48.6
WP_001138082.1\|30975_33861_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-190	39.9
WP_001044768.1\|33921_34338_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_001261287.1\|34334_34565_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_000111771.1\|34860_35151_+	hypothetical protein	NA	NA	NA	NA
WP_000963206.1\|35140_36040_+	nucleotide-binding protein	NA	NA	NA	NA
WP_000698737.1\|36089_38315_-	phage T7 exclusion protein	NA	NA	NA	NA
WP_000952217.1\|38316_39405_-	transcriptional repressor PifC	NA	NA	NA	NA
38854:38868	attL	NA	NA	NA	NA
WP_000465036.1\|39956_40370_+	hypothetical protein	NA	NA	NA	NA
WP_001164198.1\|40371_41151_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	4.0e-55	95.6
WP_001144036.1\|41329_41974_+	ParA family protein	NA	NA	NA	NA
WP_000030199.1\|42060_42369_+	hypothetical protein	NA	NA	NA	NA
WP_000688514.1\|42782_43763_+	recombinase	A0A0A7NPX4	Enterobacteria_phage	1.7e-79	51.4
WP_001278818.1\|43755_44172_+	recombinase	NA	NA	NA	NA
WP_000457492.1\|44173_45448_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	1.7e-143	60.2
WP_000109071.1\|45447_45885_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.3e-26	48.4
WP_000618110.1\|45881_46130_-	DinI-like family protein	Q2A098	Sodalis_phage	1.9e-14	48.0
WP_000273918.1\|46547_47450_+	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_000086178.1\|47834_48518_+	DNA methylase	A0A2I7RE86	Vibrio_phage	1.0e-30	37.4
WP_001104887.1\|48518_48740_+	hypothetical protein	NA	NA	NA	NA
WP_000274403.1\|48751_49186_+	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_015059345.1\|49879_50452_+	YubH family protein	NA	NA	NA	NA
WP_072132163.1\|50547_50850_+	antirestriction protein	NA	NA	NA	NA
WP_000271729.1\|50896_51319_+	DUF1380 family protein	NA	NA	NA	NA
WP_001027500.1\|51315_51507_+	hypothetical protein	NA	NA	NA	NA
WP_001276110.1\|52276_52804_+	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	1.6e-47	73.5
WP_000006014.1\|52861_53095_+	DUF905 domain-containing protein	NA	NA	NA	NA
WP_001145453.1\|53153_55112_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	3.6e-20	28.9
53098:53112	attR	NA	NA	NA	NA
WP_000845897.1\|55166_55601_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_001276261.1\|55597_56317_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_000978012.1\|56313_56910_+	hypothetical protein	A0A0N7KZV3	Escherichia_phage	3.1e-15	61.9
WP_000117609.1\|57372_57873_+	antirestriction protein ArdA	G9FHQ1	Rhodococcus_virus	9.3e-05	26.9
WP_000218863.1\|58601_59036_+	hypothetical protein	NA	NA	NA	NA
WP_001247862.1\|59127_59394_+	hypothetical protein	NA	NA	NA	NA
WP_039023393.1\|59458_60400_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	2.7e-61	51.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP025753

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP025752

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP025751

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection