CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP026316	Vibrio campbellii strain BoB-90 chromosome 2, complete sequence	1 crisprs	csa3,cas3	0	4
NZ_CP026315	Vibrio campbellii strain BoB-90 chromosome 1, complete sequence	0 crisprs	cas3,csx1,DinG,csa3,DEDDh	0	8
NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	2 crisprs	cas5,cas7,cas6e,cse2gr11,cas8e	10	1
NZ_CP026319	Vibrio campbellii strain BoB-90 plasmid unnamed 3, complete sequence	0 crisprs	RT	0	0
NZ_CP026320	Vibrio campbellii strain BoB-90 plasmid unnamed 4, complete sequence	0 crisprs	NA	0	1
NZ_CP026318	Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence	1 crisprs	NA	4	3

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

6187 : 31789

Staphylococcus_phage(28.57%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103410392.1\|6187_7231_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_103412350.1\|7300_7885_-	hypothetical protein	NA	NA	NA	NA
WP_079400830.1\|7923_8055_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412351.1\|8018_8444_+	hypothetical protein	NA	NA	NA	NA
WP_158652735.1\|8594_8810_-	hypothetical protein	NA	NA	NA	NA
WP_103410833.1\|8750_9719_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	3.3e-43	37.5
WP_017821410.1\|10258_10390_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412353.1\|10878_11004_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412354.1\|11256_11751_+	hypothetical protein	NA	NA	NA	NA
WP_103412355.1\|11909_12452_-	hypothetical protein	NA	NA	NA	NA
WP_103412376.1\|12484_12607_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412377.1\|12615_13203_-	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_103412356.1\|13363_13867_-	hypothetical protein	NA	NA	NA	NA
WP_080338381.1\|13893_14025_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412357.1\|14111_14462_+	hypothetical protein	NA	NA	NA	NA
WP_103412378.1\|14513_14690_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412358.1\|14720_15689_+\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	3.3e-43	37.5
WP_103412359.1\|15721_16483_-	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|16584_17381_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_103412379.1\|17411_17510_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412362.1\|17998_18121_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412363.1\|18117_18417_-	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|19619_20416_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_103412364.1\|20457_20859_-	hydrolase	NA	NA	NA	NA
WP_103412380.1\|21002_21500_-	HNH endonuclease	NA	NA	NA	NA
WP_103410827.1\|21877_22729_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.8e-56	44.7
WP_103412365.1\|23777_24407_-	hypothetical protein	NA	NA	NA	NA
WP_103412366.1\|24434_24566_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103412367.1\|24652_24916_+	hypothetical protein	NA	NA	NA	NA
WP_103412368.1\|25179_25971_-	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_079855550.1\|26003_26135_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_080765011.1\|26622_26715_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_158652736.1\|26729_27134_-	hypothetical protein	NA	NA	NA	NA
WP_158652737.1\|27279_27855_-	AAA family ATPase	A0A2H4JFX6	uncultured_Caudovirales_phage	1.2e-45	51.6
WP_005398409.1\|27964_28249_+	DNA-damage-inducible protein J	NA	NA	NA	NA
WP_017035198.1\|28245_28524_+	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	NA	NA	NA	NA
WP_103412371.1\|28552_28684_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410392.1\|29068_30112_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_103410819.1\|30259_31789_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	3.0e-70	34.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP026316

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP026316_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026316_1

1287663-1288234

Orphan

Consensus_repeat	Method
ACATTAGATGTATCCCAGTGACCTATATCTTG	CRISPRCasFinder

7 spacers

The CRISPR arrays of NZ_CP026316_1

>merge|NZ_CP026316|1|1287663-1288234|CRISPRCasFinder
ACATTAGATGTATCCCAGTAACCTATATCTTGGTCAAAGGCATCTGCACTATAGAACATGCTGCTCATTAACCTGACTTGAGATGTATCCCAGCGACCTATATCTTGATTAAAGGCATCAGCAGTAGTAAACATGCCTTGCATATACTTTACATTTGATGTGTCCCAATAACCTATATCTTGGTTGAAAACTTTGGCTCCTCTGAACATATCACTCATATCCGATACATTTGATGTGTCCCAATAACCTACATCTTGGTTGAATTTGAAAGCACTATAAAACATGCCTTTCATACTCCGTACATTAGATGTATCCCAGTGACCTATATCTTGATTGAAGTTGTAAGCCCCCCTAAACATGCCAATCATCTCCGTCACATTCGATGTATCCCAGTGACCTATATCTTGGTTAAATTTTATCTTATTGAACGAGTTAAATTTACCGAACATATAAAGCATTGAGGTGACTTTTGACGTGTCCCAGTGACCAATATCCTGGTTAAATTCATACGCTCCACTAAACATATGAGCCATATTTATTACATTCGATGTATCCCAATCGCTAATATCAGC

>NZ_CP026316|1|1|1287663-1288234|CRISPRCasFinder
ACATTAGATGTATCCCAGTAACCTATATCTTG	GTCAAAGGCATCTGCACTATAGAACATGCTGCTCATTAACCTG
ACTTGAGATGTATCCCAGCGACCTATATCTTG	ATTAAAGGCATCAGCAGTAGTAAACATGCCTTGCATATACTTT
ACATTTGATGTGTCCCAATAACCTATATCTTG	GTTGAAAACTTTGGCTCCTCTGAACATATCACTCATATCCGAT
ACATTTGATGTGTCCCAATAACCTACATCTTG	GTTGAATTTGAAAGCACTATAAAACATGCCTTTCATACTCCGT
ACATTAGATGTATCCCAGTGACCTATATCTTG	ATTGAAGTTGTAAGCCCCCCTAAACATGCCAATCATCTCCGTC
ACATTCGATGTATCCCAGTGACCTATATCTTG	GTTAAATTTTATCTTATTGAACGAGTTAAATTTACCGAACATATAAAGCATTGAGGTG
ACTTTTGACGTGTCCCAGTGACCAATATCCTG	GTTAAATTCATACGCTCCACTAAACATATGAGCCATATTTATT
ACATTCGATGTATCCCAATCGCTAATATCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026316.1\|WP_050919066.1\|1294205_1295114_-\|aldo/keto-reductase-family-oxidoreductase	unknown	unknown	gnl\|CDD\|227322
NZ_CP026316.1\|WP_005425931.1\|1278598_1279870_-\|CpaF-family-protein	unknown	unknown	gnl\|CDD\|227297
NZ_CP026316.1\|WP_005425883.1\|1284379_1284586_-\|Flp-family-type-IVb-pilin	unknown	unknown	gnl\|CDD\|368212
NZ_CP026316.1\|WP_103411693.1\|1298511_1299477_+\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_CP026316.1\|WP_103411689.1\|1289297_1290341_-\|GMP-reductase	unknown	unknown	gnl\|CDD\|235343
NZ_CP026316.1\|WP_005425987.1\|1292879_1293884_-\|response-regulator	unknown	unknown	gnl\|CDD\|381124
NZ_CP026316.1\|WP_038888437.1\|1296862_1298269_+\|H(+)/Cl(-)-exchange-transporter-ClcA	unknown	unknown	gnl\|CDD\|235385
NZ_CP026316.1\|WP_103411685.1\|1276855_1277698_-\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|224975
NZ_CP026316.1\|WP_005425953.1\|1285052_1285943_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP026316.1\|WP_047476122.1\|1282953_1283778_-\|pilus-assembly-protein-CpaB	unknown	unknown	gnl\|CDD\|274472
NZ_CP026316.1\|WP_103412078.1\|1295641_1296079_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026316.1\|WP_079401317.1\|1281583_1282954_-\|pilus-assembly-protein-CpaC	unknown	unknown	gnl\|CDD\|227299
NZ_CP026316.1\|WP_103411686.1\|1283799_1284237_-\|peptidase	unknown	unknown	gnl\|CDD\|227295
NZ_CP026316.1\|WP_103411691.1\|1292439_1292880_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|366402
NZ_CP026316.1\|WP_005425857.1\|1281110_1281587_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026316.1\|WP_005425870.1\|1277694_1278597_-\|type-II-secretion-system-protein-F	unknown	unknown	gnl\|CDD\|227300
NZ_CP026316.1\|WP_045379884.1\|1279866_1281108_-\|chromosome-partitioning-protein-ParA	unknown	unknown	gnl\|CDD\|366743
NZ_CP026316.1\|WP_103411688.1\|1288524_1288962_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP026316.1\|WP_103411690.1\|1290790_1292329_-\|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl\|CDD\|182554
NZ_CP026316.1\|WP_103411692.1\|1295210_1295630_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045

Protein	Function_ID	Function_description	E-value
NZ_CP026316.1\|WP_050919066.1\|1294205_1295114_-\|aldo/keto-reductase-family-oxidoreductase	gnl\|CDD\|227322	COG4989, COG4989, Predicted oxidoreductase [General function prediction only].	6.94642e-174
NZ_CP026316.1\|WP_005425931.1\|1278598_1279870_-\|CpaF-family-protein	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	1.72395e-148
NZ_CP026316.1\|WP_005425883.1\|1284379_1284586_-\|Flp-family-type-IVb-pilin	gnl\|CDD\|368212	pfam04964, Flp_Fap, Flp/Fap pilin component.	1.129e-07
NZ_CP026316.1\|WP_103411693.1\|1298511_1299477_+\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	3.87473e-84
NZ_CP026316.1\|WP_103411689.1\|1289297_1290341_-\|GMP-reductase	gnl\|CDD\|235343	PRK05096, PRK05096, guanosine 5'-monophosphate oxidoreductase; Provisional.	0
NZ_CP026316.1\|WP_005425987.1\|1292879_1293884_-\|response-regulator	gnl\|CDD\|381124	cd17593, REC_CheC-like, phosphoacceptor receiver (REC) domain of uncharacterized response regulators containing a CheC domain. This subfamily is composed of uncharacterized proteins containing an N-terminal REC domain and a C-terminal CheC domain that may function as the output/effector domain of a response regulator. CheC is a CheY-P phosphatase, affecting the level of phosphorylated CheY which controls the sense of flagella rotation and determine swimming behavior of chemotactic bacteria. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.8751e-59
NZ_CP026316.1\|WP_038888437.1\|1296862_1298269_+\|H(+)/Cl(-)-exchange-transporter-ClcA	gnl\|CDD\|235385	PRK05277, PRK05277, H(+)/Cl(-) exchange transporter ClcA.	0
NZ_CP026316.1\|WP_103411685.1\|1276855_1277698_-\|type-II-secretion-system-F-family-protein	gnl\|CDD\|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	9.0693e-15
NZ_CP026316.1\|WP_005425953.1\|1285052_1285943_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.39218e-35
NZ_CP026316.1\|WP_047476122.1\|1282953_1283778_-\|pilus-assembly-protein-CpaB	gnl\|CDD\|274472	TIGR03177, pilus_cpaB, Flp pilus assembly protein CpaB. Members of this protein family are the CpaB protein of Flp-type pilus assembly. Similar proteins include the FlgA protein of bacterial flagellum biosynthesis.	2.57856e-13
NZ_CP026316.1\|WP_079401317.1\|1281583_1282954_-\|pilus-assembly-protein-CpaC	gnl\|CDD\|227299	COG4964, CpaC, Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion].	3.68089e-75
NZ_CP026316.1\|WP_103411686.1\|1283799_1284237_-\|peptidase	gnl\|CDD\|227295	COG4960, CpaA, Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	1.20833e-08
NZ_CP026316.1\|WP_103411691.1\|1292439_1292880_-\|PAS-domain-containing-protein	gnl\|CDD\|366402	pfam00989, PAS, PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.	0.000112642
NZ_CP026316.1\|WP_005425870.1\|1277694_1278597_-\|type-II-secretion-system-protein-F	gnl\|CDD\|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	4.63689e-39
NZ_CP026316.1\|WP_045379884.1\|1279866_1281108_-\|chromosome-partitioning-protein-ParA	gnl\|CDD\|366743	pfam01656, CbiA, CobQ/CobB/MinD/ParA nucleotide binding domain. This family consists of various cobyrinic acid a,c-diamide synthases. These include CbiA and CbiP from S.typhimurium, and CobQ from R. capsulatus. These amidases catalyze amidations to various side chains of hydrogenobyrinic acid or cobyrinic acid a,c-diamide in the biosynthesis of cobalamin (vitamin B12) from uroporphyrinogen III. Vitamin B12 is an important cofactor and an essential nutrient for many plants and animals and is primarily produced by bacteria. The family also contains dethiobiotin synthetases as well as the plasmid partitioning proteins of the MinD/ParA family.	3.98077e-08
NZ_CP026316.1\|WP_103411688.1\|1288524_1288962_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.13686e-20
NZ_CP026316.1\|WP_103411690.1\|1290790_1292329_-\|NAD(P)H-hydrate-dehydratase	gnl\|CDD\|182554	PRK10565, PRK10565, putative carbohydrate kinase; Provisional.	2.66676e-160
NZ_CP026316.1\|WP_103411692.1\|1295210_1295630_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00778124

>NZ_CP026316.1|WP_005425953.1|1285052_1285943_+|LysR-family-transcriptional-regulator
MKLQFENIVSFVAVVEEGSFSSAARKLGKSQSTVSTAVQNLESDLGFNLFNRQYSKVWLTEKGKRLFHLSAPVVSKYRELMTTAQQMNISEQIVYRVGIDPLVFNKEVKKTLLDFSEAFPNVDLLVVTKPSFVLGNYINEGKIDLALGNPYHKTGNDFNIDELFYVNCWWVAHEALTNIDSNPSQRVLLMDGSEELLNLSNIAAYNLWRLDDLGTILDLCKAQKGIAFLPEFLIEENEKESKLRRINDHPDLFGKRVTASLFWPTHSDFSLFNQWIKGELRSSVAPQPKFMADLAQ
>NZ_CP026316.1|WP_005425883.1|1284379_1284586_-|Flp-family-type-IVb-pilin
MITKLYVQTSLFLSKFKNDERGVTAIEYGLIAVAMAVLVTTAVGSDGFIGKLEGAFDQVAGAIDTASK
>NZ_CP026316.1|WP_103411686.1|1283799_1284237_-|peptidase
MSYELYLLVLFIVCLYVSIVDLLHRKIHNHTLFILLFFQCFLSPLDLQFITFLLMLGSGLILYALIWVGAGDIKYAAVLSLVIPLKDLPWSLVMTAFAGGFLAIIYLVSRKLVTNTSNTQEGIPYGIAISIGFYLIILTQNTPHI
>NZ_CP026316.1|WP_047476122.1|1282953_1283778_-|pilus-assembly-protein-CpaB
MRSRLVLLVAIVALIVGALGVIDLFKSDPQPIAAAAVVENTNEEYVAVWMTTEAYEKGHAISAQGVVKQQLPLNEALALGVREDAQISFSPSILLNRSLDLGDVVLPEYQVSPGQPGYIDLLVTEGMTLYPLEVSDQNLINDYIRPGSFIDILTVSSPNDNLAQNIDKPKRFKGVKASMFLKHVKVLNIGDDAKGDSSVTARSPSKENGLTTVVIEVKPDDLAKLALAQRTMHIEIYRSQTYNKPEYAEVRNVIDNYTGIEELRGNVIDRREAL
>NZ_CP026316.1|WP_079401317.1|1281583_1282954_-|pilus-assembly-protein-CpaC
MVIQPRISQSLSIFIASLFFCLFFVTKTHAADRSITLNDGQHISVKQPIGKVFISNPDVADYKVINDTTLVVFANGIGQSRLIVYGIDEDVLLSDRIIVDLDLTEIRRQLKFHFPDAKVTVQSVGEQVAVGGVVDSEETRDEIYRLVATLLGREKTEKWDKTYKFEFKSDYAQYEEPEGMIFARNMTWKGIVERIQVATTQQVNVKISVAQVTESFGKTVGVDWSSVGSSVGEFVFDQFDAANLSTLITALGNDQVAEVLAEPNLTVLSGESASFLVGGEVPVIVSTNNNVNISFKEFGIKLDLTAKVLSQDKIRMQLAPEVSEIESYVEAAGVKVPQLASRRALTTVELADGDSFILGGLMSSADLEKMQKIPFVGDIPILGAAFRKATTERKRTELIIVATVNLVEPIKPKDVQLPYIKKTSTLARWLNIESNKDSIASSDATIRLLSEGGFIQ
>NZ_CP026316.1|WP_005425857.1|1281110_1281587_-|hypothetical-protein
MKNLVFIALLTSSLLGCANERYFGGNGAEAIVYKENHSFEFAIKKRTETAKKIEQLIRDIESMDKGATYVVEYKSTRAKTMLEPIFKQYPAHIIAPQRVEYRSRPSLSSDLNIHVTLTRLKTQQCLPAKFQARIGQPDCFVESMRLKQVSDKSRLIGE
>NZ_CP026316.1|WP_045379884.1|1279866_1281108_-|chromosome-partitioning-protein-ParA
MFDLTKALTTKAKPAPSTTTGVAGCTLFYQSQECLNLVQEVFRFEGWNDPECVKANSGSTKLTEQQSSHIVILELNESRSVVEDAKAFASKVPTHKGVVVIGKEDAISTLRSLKEMGFYYVFWPVNKQEFADFLNHVNKNLKTFSGVSQKRKAKRVAVVGSKGGVGASFITTELSSLLSTQGSDTILVDHQYADTNIDVLLGLKDFKSRAIDEFTAPLHEMDEEGALSYLFNARKNLRVLAIDGDMSQNDILNYNQTLCDLLARNTNFIIEDFSGGVDFKVEPQLLVENFDVVVLVLDASVSSTRSAKRLFEKMANLQLTLSSRTRVITVVNYHRPENAYVLQKPDLPKYLGASVDLEVDYCKSLSHIIIDGKRAHKHDRNISRSMEQLVKLINGQPVTQKGMGSWLKRVRVK
>NZ_CP026316.1|WP_005425931.1|1278598_1279870_-|CpaF-family-protein
MSSNKDLYLAFRGQIFEALDAEAVQKMSRRDLESQIQAAVDLLANNYQRPITSMMKSGLVKSLIDELFGLGPLQPLVEDQSISDIMVNGPNNIFFERHGKVQKSEVSFVNEEQLLAIAKRIASRVGRRVDELSPTVDARLEDGSRVNIVIPPIALDGTSISIRKFREQNIGFEDLIGFGSMSPDMARVLMIASRCRMNVLISGGTGSGKTTLLNALSQYIAEDERIVTIEDAAELRLQQPNLVRLETRTSSVEQTGAVNQRDLVINALRMRPDRIILGECRGSEAFEMLQAMNTGHDGSMSTLHANTPRDAIARVESMVMMANLNQPLDAIRRTIVSAVQMIVQVNRLRDGSRKITSISEIVGLEGDSVVMEEIYRFRYDDTHFGETVKGDFVTSGIMQRSELVKKAQFFGLYDELMASFKGI
>NZ_CP026316.1|WP_005425870.1|1277694_1278597_-|type-II-secretion-system-protein-F
MLWLSLILFAFVLLLVRDSKVKKVDQFFNIEEVEAENFNAINVKSLVRKQSWQKFKESISPTLKVLGPRSSLYIALYITGSLIVSWYFVVKLLLMSSIWLTLGLSVLLTLFGYRYLVTRRRRDFENTFPDALNILMSAVTAGDSLMQAISYVGDVMDNSIGREFKLMGDRLKLGESPEVVLQRSCKNYPYPEFLFFTVTLRANIARGGQLKGVLARLIRVLVDARTLEKKKMAMTSEARISAKIVAAIPLIFMIILNYVNPDNVNFVLYDPSGRLVLFYVLGSEFFGLFIVWLLVRGVRA
>NZ_CP026316.1|WP_103411685.1|1276855_1277698_-|type-II-secretion-system-F-family-protein
MMLLTALIVLFVSLLFLIFDSLRTEQRRKKIALYIGGNAHRSPSRVNRFFVRFGKEHRQELEQKMIEAGYYNTEWAKFYFPAKLLVLGLVSGFVLLSDMTQSNQLIVITFTLIAVIVGPDSLLQMRRKILIRKTSAQLPYLLDMMSVCVQTGMTIEAALVYLGKELAEFDSDLCYQIKRTSDSAKIHGLEKALNDLSERIPTPPIRSFVLTIIQNLQYGTSVAQVLSDLAEDMRKVQILTVEEKVGKLSAKMSVPLILFIMFPIVILILAPGIMQMTLNI
>NZ_CP026316.1|WP_103411688.1|1288524_1288962_-|BspA-family-leucine-rich-repeat-surface-protein
MKLRSIISACLLLSCSQTFANESETVTCESNKPGTVMVQEDELFVVVNDMLIRNSDYWQNFLDGNILLCTSHVTDMSDLFAKDQYFNQDISRWDTSRVTNMDRMFSGAKRFDQDLTYWNVKRVSRHTDFAKDSGLSEDNLPTFTQ
>NZ_CP026316.1|WP_103411689.1|1289297_1290341_-|GMP-reductase
MRIEQELKLGFKDVLFRPKRSTLKSRSQVNLTRDFTFKHSGRQWSGVPVIAANMDSVGSFAMAKALAEHGVMTAVHKHYTVEDWAEFAKTADKATLNNVMVSTGTSEADFQKTKDIMATSDEFIFICIDIANGYSEHLVEYVQRVRAAFPDKVISAGNVVTGDMCEELILAGADIVKVGIGPGSVCTTRVKTGVGYPQLSAIIECGDAAHGLGGMIIGDGGCSCAGDVAKAFGGGADFVMLGGMLAGHEESGGEVIEQDGKKFMKFYGMSSKSAMDKHSGGVAGYRAAEGKTVLLPFRGSVHGTIQDILGGVRSTCTYVGAAKLKELTKRTTFIRVQEQENNVFGKE
>NZ_CP026316.1|WP_103411690.1|1290790_1292329_-|NAD(P)H-hydrate-dehydratase
MDFNLALKLYTAEQVRNGEVIAAQMAGVSMYSLMQRAGMAVYERFLHLYPKARTVLVVCGKGNNGGDGYVFATLAKQAQLNVRVFQLGDTTALKGDALRAFEDWQSVDGENSSWDDWHTALLEVDVIIDAMLGTGLSGEVRHEYRRYIDQVNQIHCPVISIDIPSGLSSDTGSVLGDAIQANHTVTFIGVKQGLCTGQARDYVGKLHFSGLGVNVEFESIEEESALGIDHLIIRRLLPERKATAHKGHNGKLLCIGGNQGMSGAIRLCASAAVRTGAGLTAALTHPSSLLPLQVGSPEVMSQAITFDELKEQDNELIKRTRWADALAFGPGFGEDEWAHQAYQLLSQQHKPKVVDADGLNILAMLNQRNDVVVLRDEQRVMTPHPGEAARLLNVSTKEIEQDRFAAARQLHERYGGVVVLKGAGTLIFDGGRMYVCLAGNPGMASGGMGDVLSGVIAALLAKGLPIAVAARLGVMLHSHAADINVQQKGEIGLLASDVIESLRDAINLKNDY
>NZ_CP026316.1|WP_103411691.1|1292439_1292880_-|PAS-domain-containing-protein
MLNLPAEFEQFHWMVDMVQNVDMGLVVIDKDYNVQVWNGFMTHHSGLQSHEAIGRSIFDIFPEIPQEWFKLKTKPVYDLGCRSFITWRQRPYLFRCRNVRPVTQQAEFMYQNVTLNPMRTPIGKINSLFLSIQDATAEALMSQQQT
>NZ_CP026316.1|WP_005425987.1|1292879_1293884_-|response-regulator
MSFPVLICDDSALARKQMARSLPATLNADVTFAIHGKNALEELAQKEFKLMFLDLTMPEMDGFETLENMKRLGIQTPVVVVSGDIQPKAKERVFALGAKAFIQKPIGKDELKATLKELIEPNDRPQVITPTTIELPILRRRDIYMEVANVSIGRAADALARHFDVFVQLPLPNVNIFEVSELHMALRDLASHDNVSGVCQGFCGEGIAGEALVILSDSSVSDLKKLMKVPADSEELEELELLMDISNILVGSFLNGLGEQSEVRFFQSSPVLLGQHISIDSIIESTTGAFSRTMTFEVSYNIEGTSIRCDLLFMFVDESLPLLDNKLSYLMEDF
>NZ_CP026316.1|WP_050919066.1|1294205_1295114_-|aldo/keto-reductase-family-oxidoreductase
MVAKVVTAPNGPEFSELVQGYWRAVDWGMTAQERLSFLKQHIELGITTVDHADIYGNYECEALFGEALALDKSIREQIQIVTKCDINLCGDKTPERKINHYDTSAAHIYQSVNNSLERLKVDEIDVLLIHRPDVLMDADEVAEAFSELHKVGKVKHFGVSNFTPRQFELLQSRLSKPLVTNQVEINPLNFEVAHDGTLDLLQTHRVRPMAWSCLGGGSIFTGDTEQAVRVRNELEAIREEVGANSIDEVIYAWVRRLPSKPMPIIGSGKIERVQAAVNALNIELTREQWYRVWVASKGHGVP
>NZ_CP026316.1|WP_103411692.1|1295210_1295630_+|helix-turn-helix-transcriptional-regulator
MSFAQRLATLIGEESISGFARRVDVSEALIRKYLKGSEPSLTKANQIAMRANCSLEWLATGCGYLYRQAEVVDMGAYKLAFQHVMSGTISQVEEAQHRKLIAGYQYLRAHKKSDGFLDESAMATFLALHHENKTETSES
>NZ_CP026316.1|WP_103412078.1|1295641_1296079_-|hypothetical-protein
MQEGGEWYTCEAQESTDAFCLDDFHYYQQHLYGEANAEAKAIRLIFLTEYQPQNLSELILNLRKDGLVMKRIAIQGEQYDVAAALKHNSPEAVDKALVLFINRYPQQVPRRIDWVLAQEFGSPAPRLNVTLNSDGEMIELEVIRF
>NZ_CP026316.1|WP_038888437.1|1296862_1298269_+|H(+)/Cl(-)-exchange-transporter-ClcA
MTKRERIVKSVLAHVPKDAINQFVSRGSTPTSFSVLFMAAIVGTLAGLVGTYFEIAVHFVSETRTEWLKSEIGSVLPLWLAAILISGALAFIGYYLVHRFAPEASGSGIPEIEGAMDNIRPVRWWRVIPVKFFGGMGALGSGMVLGREGPTVQMGGAVGRMVTDIFRVKDDDTRHSLLASGAAGGLAAAFNAPLAGIMFVVEEMRPQFRYSLISIRAVIISAIMANIVFRAINGQEAVITMPQYQSPELQSLWLFLLLGSLFGVFGVVFNKLITIAQDSFVALHKNDRKRYLITGTILGGVFGLLLLYVPQLTGGGIGLIPDITNGNYSISILVMLFVGRVITTLLCFGSGAPGGIFAPMLALGTLFGYAFGASADMLLPSLTIEPGVFAIAGMGALFAATVRAPITGILLVIEMTNNYYLILPLIITSLGAVIVAQLLGGQPIYSQLLHRTLKNDKLRQQDLPENQA
>NZ_CP026316.1|WP_103411693.1|1298511_1299477_+|TDT-family-transporter
MNWRRLVQFYSVPPSQAALALGMIGLGQAWALYIPEIGEPIRPFLAALGALFLTPVLLKYATSPRLFMADIKHPLSGSLMAPMSMALLMLCDYLAAVAPIIAYPLWFMAVLLHFTMMVLFFGFQIMNFKMSNIVPSWFLYPVGLISSSLAGSQFGHNVFSETLAMMCIGIYFFMLPLVLYRLVFFGSLPRRARPTLAIMAAPVNLSLAAYLVNFGEPDPILTGALAGIAITMTLLIYLCYFRLMRLKFQPSIAAVTFPSVISAIAMHRLTTFFAESYPQWHWLHDFGFLELSVATVLVVWVSAGYVKMYWPELIRTPSKQI

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

861558 : 868262

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103411510.1\|861558_861927_-	hypothetical protein	Q9MCC3	Vibrio_phage	3.6e-46	79.3
WP_051116825.1\|862122_862524_+	hypothetical protein	NA	NA	NA	NA
WP_005531344.1\|862527_862743_+	hypothetical protein	A0A1W6UGD1	Vibrio_phage	7.2e-31	87.3
WP_103411511.1\|862726_863872_+	phage replication protein	A0A1W6UG38	Vibrio_phage	9.0e-213	92.1
WP_045373564.1\|863875_864229_+	DUF1293 family protein	Q783U4	Vibrio_phage	3.9e-58	96.5
WP_103411512.1\|864237_864468_+	transcriptional regulator	R9TMT7	Vibrio_phage	2.5e-05	38.2
WP_042605493.1\|864481_864712_+	hypothetical protein	Q783U2	Vibrio_phage	1.7e-06	50.7
WP_103411513.1\|864839_866513_+	hypothetical protein	NA	NA	NA	NA
WP_045373574.1\|866514_866859_+	hypothetical protein	NA	NA	NA	NA
WP_103411514.1\|866861_868262_+	zonular occludens toxin	Q783T9	Vibrio_phage	5.7e-84	40.4

DBSCAN-SWA_2

956785 : 1010538

Sulfolobus_monocaudavirus(16.67%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086028371.1\|956785_957581_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_086028371.1\|959746_960542_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_103411555.1\|960634_962341_-	D-lactate dehydrogenase	NA	NA	NA	NA
WP_103411556.1\|962789_963692_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_103411557.1\|963858_967146_-	glycoside hydrolase family 3 protein	NA	NA	NA	NA
WP_103411559.1\|968018_969473_-	ATPase RavA stimulator ViaA	NA	NA	NA	NA
WP_045417366.1\|969482_971144_-	DUF3763 domain-containing protein	A0A0N9PBE1	Sulfolobus_monocaudavirus	1.9e-17	22.3
WP_103411560.1\|971415_971931_+	NUDIX hydrolase	NA	NA	NA	NA
WP_103411561.1\|971955_972960_+	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_047481918.1\|973041_973368_+	cytochrome c	NA	NA	NA	NA
WP_080992052.1\|973586_975119_+	putative basic amino acid antiporter YfcC	NA	NA	NA	NA
WP_103411562.1\|975264_976260_+	succinylglutamate desuccinylase/aspartoacylase family protein	NA	NA	NA	NA
WP_103411563.1\|976373_977495_-	multidrug effflux MFS transporter	NA	NA	NA	NA
WP_103412070.1\|977631_978411_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005444070.1\|978428_978950_-	hypothetical protein	A0A1W6JNX6	Morganella_phage	7.1e-40	46.2
WP_103411564.1\|979006_979534_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_103411565.1\|979976_980630_-	amino-acid racemase	NA	NA	NA	NA
WP_038891249.1\|980700_980946_-	hypothetical protein	NA	NA	NA	NA
WP_103411566.1\|981063_981606_-	adenylate kinase	NA	NA	NA	NA
WP_103411567.1\|982060_983743_-	DUF5011 domain-containing protein	NA	NA	NA	NA
WP_038891246.1\|984116_984497_+	pyruvate dehydrogenase	NA	NA	NA	NA
WP_103411568.1\|984583_987640_-	SMC family ATPase	E3SMW4	Prochlorococcus_phage	4.6e-06	22.4
WP_103411569.1\|987649_988789_-	exonuclease SbcCD subunit D	G3MA97	Bacillus_virus	8.3e-09	22.0
WP_050904609.1\|989153_989480_-	hypothetical protein	NA	NA	NA	NA
WP_103411570.1\|993863_994694_-	NAD/NADP transhydrogenase beta subunit	NA	NA	NA	NA
WP_032802378.1\|994694_994985_-	type VI secretion protein	NA	NA	NA	NA
WP_103411571.1\|994997_996833_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.2e-26	26.7
WP_005426862.1\|996883_997363_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_103411572.1\|997570_1000135_-	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	1.2e-87	28.8
WP_103411573.1\|1000145_1001108_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_045401266.1\|1001104_1002928_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_103411574.1\|1002924_1003389_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_045372117.1\|1003397_1004195_-	protein of avirulence locus	NA	NA	NA	NA
WP_045417400.1\|1004204_1005716_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_103411575.1\|1005797_1007291_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_005426987.1\|1007290_1007821_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_103411576.1\|1007836_1008976_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_103411577.1\|1008968_1009757_-	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_086028371.1\|1009741_1010538_-\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1219646 : 1261267

Hokovirus(22.22%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086028371.1\|1219646_1220442_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_005431784.1\|1220526_1221534_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_012129637.1\|1221551_1222469_-	ribokinase	NA	NA	NA	NA
WP_005431772.1\|1222671_1223550_-	ribose ABC transporter substrate-binding protein RbsB	C6ZCU4	Enterobacteria_phage	7.3e-05	22.7
WP_005431792.1\|1223641_1224625_-	ribose ABC transporter permease	NA	NA	NA	NA
WP_045370858.1\|1224621_1226127_-	ribose ABC transporter ATP-binding protein RbsA	A0A2H4PQG7	Staphylococcus_phage	2.6e-18	28.2
WP_038888346.1\|1226151_1226571_-	D-ribose pyranase	NA	NA	NA	NA
WP_103411663.1\|1227111_1229448_+	EAL domain-containing protein	NA	NA	NA	NA
WP_103411664.1\|1229541_1230297_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_103411665.1\|1230642_1231353_-	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_045403186.1\|1231361_1231979_-	NUDIX hydrolase	NA	NA	NA	NA
WP_045403188.1\|1232167_1232578_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_038888350.1\|1233152_1233794_+	murein L,D-transpeptidase catalytic domain family protein	NA	NA	NA	NA
WP_155399346.1\|1233879_1234095_-	hypothetical protein	NA	NA	NA	NA
WP_050910282.1\|1234506_1234824_+	hypothetical protein	NA	NA	NA	NA
WP_005431873.1\|1234909_1235587_-	DedA family protein	NA	NA	NA	NA
WP_050904471.1\|1235637_1236045_-	hypothetical protein	NA	NA	NA	NA
WP_103411666.1\|1236182_1236701_-	DUF4136 domain-containing protein	NA	NA	NA	NA
WP_045403205.1\|1237284_1237692_-	hypothetical protein	NA	NA	NA	NA
WP_005452272.1\|1237795_1238653_-	sterol desaturase family protein	NA	NA	NA	NA
WP_103411667.1\|1238662_1239673_-	DUF2804 domain-containing protein	NA	NA	NA	NA
WP_077262950.1\|1239896_1240364_-	peroxiredoxin	NA	NA	NA	NA
WP_050914137.1\|1240483_1242847_-	response regulator	A0A1V0SGX0	Hokovirus	2.6e-57	35.6
WP_103411668.1\|1242839_1243811_-	c-type cytochrome	NA	NA	NA	NA
WP_103411669.1\|1244067_1247670_+	transporter substrate-binding domain-containing protein	A0A1V0SGX0	Hokovirus	3.1e-33	26.2
WP_045403217.1\|1247670_1248813_+	EAL domain-containing response regulator	NA	NA	NA	NA
WP_103411670.1\|1248873_1250541_+	response regulator	NA	NA	NA	NA
WP_103410153.1\|1250918_1251230_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_103410154.1\|1251226_1251580_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	9.1e-15	44.6
WP_103410155.1\|1251639_1253172_+\|transposase	IS66 family transposase	S5VTP8	Leptospira_phage	1.3e-25	39.5
WP_103411671.1\|1253316_1254684_+	nodulation protein NfeD	NA	NA	NA	NA
WP_005425980.1\|1254693_1255485_+	slipin family protein	J3IZE5	Acanthamoeba_polyphaga_lentillevirus	5.4e-23	28.1
WP_103411672.1\|1255704_1256361_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_103411673.1\|1256507_1257692_-\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.6e-26	35.8
WP_005425967.1\|1257693_1258536_-\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_005425881.1\|1258598_1259537_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_103411674.1\|1259566_1261267_-\|holin	choline dehydrogenase	A0A1V0S9J5	Catovirus	2.3e-47	28.6

DBSCAN-SWA_4

1947986 : 2008400

Enterobacteria_phage(15.38%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103411034.1\|1947986_1949231_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103411975.1\|1950003_1951458_+	PTS N-acetylmuramic acid transporter subunit IIBC	NA	NA	NA	NA
WP_103411976.1\|1951610_1952669_+	porin	NA	NA	NA	NA
WP_020197822.1\|1952893_1953142_+	hypothetical protein	NA	NA	NA	NA
WP_103411977.1\|1953138_1954041_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_103411978.1\|1954133_1954787_+	CatB-related O-acetyltransferase	A0A1V0SJ47	Klosneuvirus	4.7e-17	36.7
WP_103411979.1\|1954852_1956532_-	DUF342 domain-containing protein	NA	NA	NA	NA
WP_103411980.1\|1956979_1958998_-\|tRNA	tRNA(Met) cytidine acetyltransferase	NA	NA	NA	NA
WP_045383028.1\|1959113_1960088_-	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	4.0e-12	32.2
WP_103411981.1\|1960095_1961313_-	ParA family protein	Q1MVJ3	Enterobacteria_phage	2.9e-36	29.2
WP_103411983.1\|1962554_1964525_+	DUF3346 domain-containing protein	NA	NA	NA	NA
WP_012130353.1\|1964849_1965317_-	hypothetical protein	NA	NA	NA	NA
WP_039986455.1\|1965316_1966249_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-15	33.5
WP_103411984.1\|1966245_1967100_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.6e-17	30.5
WP_005428900.1\|1967461_1967659_+	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|1968491_1969288_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_103411985.1\|1969823_1970579_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_103411986.1\|1970647_1972573_+	response regulator	A0A1V0SGX0	Hokovirus	2.5e-58	36.7
WP_010644452.1\|1972667_1972877_+	DUF3283 family protein	NA	NA	NA	NA
WP_005428886.1\|1973012_1973729_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_005428884.1\|1973811_1974894_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_103411987.1\|1975210_1976221_-	DUF2955 domain-containing protein	NA	NA	NA	NA
WP_053050141.1\|1976231_1977281_-	HlyD family secretion protein	NA	NA	NA	NA
WP_103411988.1\|1977400_1978321_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_103411989.1\|1978405_1979074_+	hypothetical protein	NA	NA	NA	NA
WP_005448872.1\|1979082_1979781_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-41	42.2
WP_103411990.1\|1979768_1981037_+	ABC transporter permease	NA	NA	NA	NA
WP_005448874.1\|1981029_1981815_+	outer membrane lipoprotein-sorting protein	NA	NA	NA	NA
WP_103411991.1\|1981860_1983207_+	hypothetical protein	NA	NA	NA	NA
WP_103411992.1\|1983207_1984230_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	3.2e-20	30.7
WP_103411993.1\|1984246_1985038_+	response regulator transcription factor	NA	NA	NA	NA
WP_103411994.1\|1985106_1985742_+	hypothetical protein	NA	NA	NA	NA
WP_020195057.1\|1986141_1986636_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_103411995.1\|1986758_1988420_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	6.0e-16	64.5
WP_103412089.1\|1988595_1988982_-	DUF393 domain-containing protein	NA	NA	NA	NA
WP_005428854.1\|1989844_1991080_+	sodium/glutamate symporter	NA	NA	NA	NA
WP_005531275.1\|1991361_1992132_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	4.4e-06	25.1
WP_038869862.1\|1992233_1992779_+	OsmC family protein	NA	NA	NA	NA
WP_103411996.1\|1992875_1993403_-	RNA methyltransferase	A0A2D1A6G0	Rhodococcus_phage	6.1e-07	31.8
WP_103411997.1\|1993622_1994720_-	NAD(P)-binding protein	NA	NA	NA	NA
WP_005428849.1\|1994855_1995425_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_103411998.1\|1995499_1996861_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_086371233.1\|1996957_1997791_-	hypothetical protein	NA	NA	NA	NA
WP_038888606.1\|1997787_1998645_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-12	27.5
WP_005428840.1\|1998641_1999013_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_005428834.1\|1999460_2000687_+	sodium/glutamate symporter	NA	NA	NA	NA
WP_045371210.1\|2000931_2001687_+	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|2002369_2003166_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_045383074.1\|2003917_2004727_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_103410392.1\|2005139_2006183_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_086028371.1\|2006405_2007201_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_103412000.1\|2007419_2008400_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	1.3e-39	33.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP026315

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

679564 : 686255

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005440184.1\|679564_680035_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.7e-32	49.3
WP_038891655.1\|680204_681314_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	3.0e-64	39.8
WP_005424876.1\|681473_682127_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.3e-34	38.0
WP_103410186.1\|682138_683263_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	35.1
WP_005424846.1\|683270_683720_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_103410187.1\|683847_685098_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.6e-99	47.9
WP_005424865.1\|685115_686255_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.9e-62	41.4

DBSCAN-SWA_2

770305 : 777377

Megavirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005532589.1\|770305_770731_-	nucleoside-diphosphate kinase	L7Y4C4	Megavirus	2.1e-21	40.6
WP_103410215.1\|770831_772130_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	9.1e-36	34.7
WP_005424887.1\|772302_772497_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_005424889.1\|772546_772885_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_045455382.1\|772898_774752_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	9.4e-111	40.4
WP_005424897.1\|774773_775289_-	co-chaperone HscB	NA	NA	NA	NA
WP_005424893.1\|775344_775668_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	1.0e-25	51.4
WP_005424883.1\|775741_776125_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_038890722.1\|776162_777377_-	IscS subfamily cysteine desulfurase	A0A1X7C038	Faustovirus	7.4e-32	30.2

DBSCAN-SWA_3

967652 : 976878

uncultured_Mediterranean_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005528743.1\|967652_969020_+	Do family serine endopeptidase	A0A1B1IRD3	uncultured_Mediterranean_phage	4.5e-09	32.9
WP_103410253.1\|969224_970280_+	outer membrane-stress sensor serine endopeptidase DegS	A0A1B1IRD3	uncultured_Mediterranean_phage	3.7e-11	33.8
WP_103410153.1\|970356_970668_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_103410154.1\|970664_971018_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	9.1e-15	44.6
WP_103410155.1\|971077_972610_+\|transposase	IS66 family transposase	S5VTP8	Leptospira_phage	1.3e-25	39.5
WP_038890837.1\|972705_974994_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	2.0e-86	36.0
WP_010445819.1\|974997_976878_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	3.0e-96	35.7

DBSCAN-SWA_4

1822540 : 1881778

Leptospira_phage(22.22%)

tRNA,integrase,transposase

attL 1849191:1849205|attR 1870507:1870521

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103410480.1\|1822540_1823521_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_045369295.1\|1823684_1823900_+	envelope stress response protein PspG	NA	NA	NA	NA
WP_005536440.1\|1824000_1824666_+	TIGR04219 family outer membrane beta-barrel protein	NA	NA	NA	NA
WP_005451530.1\|1824819_1825050_+	hypothetical protein	NA	NA	NA	NA
WP_103410481.1\|1825167_1827042_+	assimilatory sulfite reductase (NADPH) flavoprotein subunit	NA	NA	NA	NA
WP_103410482.1\|1827041_1828778_+	assimilatory sulfite reductase (NADPH) hemoprotein subunit	NA	NA	NA	NA
WP_005536432.1\|1828770_1829550_+	phosphoadenylyl-sulfate reductase	NA	NA	NA	NA
WP_103410483.1\|1842292_1844107_+	hypothetical protein	NA	NA	NA	NA
WP_103410155.1\|1845162_1846695_-\|transposase	IS66 family transposase	S5VTP8	Leptospira_phage	1.3e-25	39.5
WP_103410154.1\|1846754_1847108_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	9.1e-15	44.6
WP_103410153.1\|1847104_1847416_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_045421043.1\|1848157_1849483_-	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	3.1e-39	37.6
1849191:1849205	attL	NA	NA	NA	NA
WP_103410484.1\|1849672_1853353_+	methionine synthase	A0A140XBC7	Dickeya_phage	1.1e-20	74.6
WP_029789692.1\|1853419_1854772_-	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_086028371.1\|1856343_1857139_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_103410485.1\|1857336_1859121_-	ligase	NA	NA	NA	NA
WP_103410486.1\|1859188_1862011_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	56.8
WP_005432802.1\|1862149_1863022_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.2e-62	46.0
WP_103410487.1\|1863186_1863831_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005432828.1\|1864124_1864661_+	single-stranded DNA-binding protein	A0A2I7RHA9	Vibrio_phage	4.5e-58	89.2
WP_103410488.1\|1864835_1866161_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_103410489.1\|1866172_1867726_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_103410490.1\|1867718_1870100_+\|integrase	integrase	NA	NA	NA	NA
WP_103410491.1\|1870105_1870522_+	hypothetical protein	NA	NA	NA	NA
1870507:1870521	attR	NA	NA	NA	NA
WP_103410492.1\|1870527_1871013_+	hypothetical protein	NA	NA	NA	NA
WP_158652667.1\|1871051_1873196_+	AAA family ATPase	A0A0N9S864	Staphylococcus_phage	4.0e-20	27.8
WP_050917706.1\|1873750_1874005_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_050917705.1\|1874139_1874394_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_103410495.1\|1874562_1874844_+	hypothetical protein	NA	NA	NA	NA
WP_158652668.1\|1875124_1875454_+	hypothetical protein	NA	NA	NA	NA
WP_103410497.1\|1875415_1875628_-	hypothetical protein	NA	NA	NA	NA
WP_102350401.1\|1875759_1876881_-	hypothetical protein	NA	NA	NA	NA
WP_103410498.1\|1876873_1877782_-	hypothetical protein	NA	NA	NA	NA
WP_103410499.1\|1878423_1879176_+	hypothetical protein	NA	NA	NA	NA
WP_103410500.1\|1879289_1880354_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_103410501.1\|1880539_1881778_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	4.7e-90	46.2

DBSCAN-SWA_5

2044755 : 2062225

uncultured_Mediterranean_phage(18.18%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005531665.1\|2044755_2046396_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.6e-154	52.1
WP_005425372.1\|2046474_2047776_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	3.5e-136	60.3
WP_005452106.1\|2048369_2048651_+	cell division protein FtsB	NA	NA	NA	NA
WP_103410536.1\|2048652_2049363_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	A0A2H4UTB4	Bodo_saltans_virus	2.4e-06	24.0
WP_103410537.1\|2049377_2049854_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_086368978.1\|2049899_2050943_+\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_080765350.1\|2050942_2051719_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.2e-67	53.7
WP_012128909.1\|2051718_2052345_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.8e-37	53.9
WP_038891105.1\|2052359_2053283_+	peptidoglycan DD-metalloendopeptidase family protein	D7RWE0	Brochothrix_phage	2.4e-06	36.4
WP_005425361.1\|2053363_2054350_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.9e-36	35.2
WP_038891104.1\|2054438_2057000_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	1.7e-33	22.7
WP_050919027.1\|2057085_2057568_+	nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	2.4e-26	47.5
WP_005436413.1\|2057768_2058812_+	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	3.1e-111	60.4
WP_005425358.1\|2059017_2059485_+	recombination regulator RecX	NA	NA	NA	NA
WP_103410538.1\|2059627_2062225_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	7.3e-77	37.5

DBSCAN-SWA_6

2684058 : 2753662

Bacillus_phage(20.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086028371.1\|2684058_2684854_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_103410061.1\|2685311_2686466_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_158652649.1\|2686474_2688550_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	3.5e-13	22.5
WP_103410059.1\|2688542_2689379_+	hypothetical protein	NA	NA	NA	NA
WP_103410058.1\|2689874_2691404_-\|transposase	IS66 family transposase	S5VTP8	Leptospira_phage	1.3e-25	39.5
WP_103410057.1\|2691463_2691817_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.0e-14	44.6
WP_103410056.1\|2691813_2692131_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|2692745_2693541_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_158652673.1\|2693602_2694109_+	hypothetical protein	NA	NA	NA	NA
WP_012128435.1\|2694071_2694602_+	hypothetical protein	NA	NA	NA	NA
WP_103410737.1\|2694696_2696139_-	pyruvate kinase	NA	NA	NA	NA
WP_005425684.1\|2696458_2697676_+	ROK family protein	NA	NA	NA	NA
WP_005425659.1\|2697912_2698854_+	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	2.0e-29	30.6
WP_103410738.1\|2699202_2702277_-	DNA polymerase III subunit alpha	A0A0K1Y9G6	Streptomyces_phage	2.9e-80	25.8
WP_103410739.1\|2702304_2703708_-	DNA polymerase Y family protein	NA	NA	NA	NA
WP_103410740.1\|2703712_2704405_-	translesion DNA synthesis-associated protein ImuA	NA	NA	NA	NA
WP_005425666.1\|2704536_2705283_-	YciK family oxidoreductase	NA	NA	NA	NA
WP_045372748.1\|2705561_2706623_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	2.6e-20	34.8
WP_005533590.1\|2706833_2707514_+	(d)CMP kinase	NA	NA	NA	NA
WP_005533588.1\|2707624_2709295_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_005431133.1\|2709508_2709793_+	integration host factor subunit beta	A0A0H3UZA0	Geobacillus_virus	3.2e-10	36.7
WP_005431104.1\|2709933_2710227_+	DUF1049 domain-containing protein	NA	NA	NA	NA
WP_005431114.1\|2710245_2711421_+	lipopolysaccharide assembly protein LapB	NA	NA	NA	NA
WP_005431048.1\|2711503_2712205_+	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_005431040.1\|2712629_2714477_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005431118.1\|2714555_2714795_-	hypothetical protein	NA	NA	NA	NA
WP_103410741.1\|2714943_2715426_-	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_103411138.1\|2715510_2716290_-	hypothetical protein	NA	NA	NA	NA
WP_103410742.1\|2716492_2717062_-	hypothetical protein	NA	NA	NA	NA
WP_005431034.1\|2717061_2718708_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_103410743.1\|2718700_2720032_-	paraquat-inducible protein A	NA	NA	NA	NA
WP_038890032.1\|2720165_2721170_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_103410744.1\|2721360_2724453_-	beta-galactosidase	L0N6M2	Herpes_simplex_virus	2.1e-309	52.4
WP_103410745.1\|2724543_2725419_-	hypothetical protein	NA	NA	NA	NA
WP_103410746.1\|2725488_2726730_-	carbohydrate porin	NA	NA	NA	NA
WP_103410748.1\|2727568_2729686_+	alpha-galactosidase	NA	NA	NA	NA
WP_103410749.1\|2730081_2731461_+	melibiose:sodium transporter MelB	NA	NA	NA	NA
WP_103410750.1\|2731562_2732462_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045400825.1\|2732691_2733000_+	hypothetical protein	NA	NA	NA	NA
WP_103410751.1\|2733062_2735174_+	cytochrome C biogenesis protein	NA	NA	NA	NA
WP_038889907.1\|2735170_2735683_+	protein disulfide oxidoreductase	NA	NA	NA	NA
WP_038889908.1\|2735788_2736418_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_155400314.1\|2736775_2736940_+	hypothetical protein	NA	NA	NA	NA
WP_103410752.1\|2736981_2737962_+	hypothetical protein	NA	NA	NA	NA
WP_103410753.1\|2737954_2738551_+	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|2738592_2739388_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_144421229.1\|2740224_2740626_+	hypothetical protein	NA	NA	NA	NA
WP_103410754.1\|2740633_2742253_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.2e-37	27.0
WP_103410755.1\|2742276_2742711_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_086369131.1\|2742785_2743556_+	phospholipase	NA	NA	NA	NA
WP_103410756.1\|2743601_2744126_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_103410757.1\|2744419_2745553_+	toxin	NA	NA	NA	NA
WP_103410758.1\|2745763_2746612_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_103410759.1\|2746779_2747916_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_103410760.1\|2747908_2749180_+	TolC family protein	NA	NA	NA	NA
WP_103410761.1\|2749176_2750421_+	ABC transporter permease	NA	NA	NA	NA
WP_103410762.1\|2750423_2751707_+	ABC transporter permease	NA	NA	NA	NA
WP_103410763.1\|2751699_2752419_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-41	43.2
WP_077200484.1\|2752678_2753662_+\|protease	YopT-type cysteine protease domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_7

2913061 : 2939689

Leptospira_phage(57.14%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103410819.1\|2913061_2914591_-\|transposase	IS66 family transposase	S5VTP8	Leptospira_phage	1.9e-24	38.9
WP_103410057.1\|2914650_2915004_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.0e-14	44.6
WP_103410056.1\|2915000_2915318_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_103410820.1\|2916244_2917129_+	hypothetical protein	NA	NA	NA	NA
WP_103410821.1\|2917262_2917751_+	hypothetical protein	NA	NA	NA	NA
WP_017821970.1\|2917777_2917870_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_004401149.1\|2917916_2918231_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_103411141.1\|2918268_2918379_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_071236632.1\|2918359_2918977_+	YdcF family protein	NA	NA	NA	NA
WP_077200621.1\|2918967_2919084_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103411143.1\|2919116_2919491_+	hypothetical protein	NA	NA	NA	NA
WP_103411142.1\|2919487_2919598_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410822.1\|2919629_2920088_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_158652674.1\|2920315_2920477_+	hypothetical protein	NA	NA	NA	NA
WP_072606010.1\|2920723_2920813_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410823.1\|2920840_2921308_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_103410824.1\|2921282_2921423_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410825.1\|2921999_2922482_+	DUF2314 domain-containing protein	NA	NA	NA	NA
WP_103410826.1\|2922749_2922953_+	hypothetical protein	NA	NA	NA	NA
WP_080335512.1\|2923121_2923211_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410827.1\|2923597_2924449_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.8e-56	44.7
WP_045409117.1\|2924611_2925127_+	hypothetical protein	NA	NA	NA	NA
WP_103410830.1\|2925821_2925932_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410827.1\|2926318_2927170_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.8e-56	44.7
WP_017191348.1\|2927223_2927565_+	hypothetical protein	NA	NA	NA	NA
WP_103410826.1\|2927841_2928045_+	hypothetical protein	NA	NA	NA	NA
WP_080335512.1\|2928213_2928303_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410831.1\|2928332_2929028_+	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_103410832.1\|2929036_2929147_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410833.1\|2929645_2930614_-\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	3.3e-43	37.5
WP_103411144.1\|2930644_2930821_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_077200588.1\|2931239_2931368_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_038140554.1\|2931375_2931693_-	CcdB family protein	NA	NA	NA	NA
WP_038140558.1\|2931692_2931938_-	type II toxin-antitoxin system CcdA family antitoxin	NA	NA	NA	NA
WP_077200589.1\|2931979_2932105_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_031850888.1\|2932141_2932453_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_079763879.1\|2932949_2933078_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_038892264.1\|2933104_2933512_+	hypothetical protein	NA	NA	NA	NA
WP_077201259.1\|2933540_2933630_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_038892273.1\|2933658_2934123_+	hypothetical protein	NA	NA	NA	NA
WP_152442079.1\|2934113_2934230_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_011080392.1\|2934263_2934761_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013571703.1\|2934757_2935030_-	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_077201260.1\|2935070_2935232_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_077200592.1\|2935325_2935745_+	hypothetical protein	NA	NA	NA	NA
WP_103410834.1\|2935756_2935909_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410819.1\|2935898_2937428_-\|transposase	IS66 family transposase	S5VTP8	Leptospira_phage	1.9e-24	38.9
WP_103410057.1\|2937487_2937841_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.0e-14	44.6
WP_103410056.1\|2937837_2938155_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_103410835.1\|2938412_2938868_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_086028371.1\|2938893_2939689_+\|transposase	IS5 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2944182 : 2975879

Leptospira_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103410827.1\|2944182_2945034_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.8e-56	44.7
WP_077200613.1\|2945084_2945597_+	hypothetical protein	NA	NA	NA	NA
WP_086371216.1\|2945578_2945704_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_077200615.1\|2945735_2946362_+	hypothetical protein	NA	NA	NA	NA
WP_079856868.1\|2946376_2946469_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_077200617.1\|2946505_2946931_+	riboflavin-specific deaminase	A0A2I2L4R9	Orpheovirus	1.3e-20	41.3
WP_103410838.1\|2947067_2947427_+	hypothetical protein	NA	NA	NA	NA
WP_079400279.1\|2947348_2947543_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410839.1\|2947570_2948035_+	hypothetical protein	NA	NA	NA	NA
WP_103411146.1\|2948537_2948654_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410819.1\|2949226_2950756_-\|transposase	IS66 family transposase	S5VTP8	Leptospira_phage	1.9e-24	38.9
WP_103410057.1\|2950815_2951169_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.0e-14	44.6
WP_103410056.1\|2951165_2951483_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_005445737.1\|2951811_2952138_+	hypothetical protein	NA	NA	NA	NA
WP_155487390.1\|2952306_2952630_+	hypothetical protein	NA	NA	NA	NA
WP_103410840.1\|2952780_2953377_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_045396921.1\|2953514_2953814_+	hypothetical protein	NA	NA	NA	NA
WP_103410056.1\|2953973_2954291_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_103410057.1\|2954287_2954641_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.0e-14	44.6
WP_103410501.1\|2954941_2956180_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	4.7e-90	46.2
WP_038892789.1\|2957717_2958302_+	hypothetical protein	NA	NA	NA	NA
WP_158652676.1\|2958328_2958430_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410501.1\|2958419_2959658_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	4.7e-90	46.2
WP_103410841.1\|2959840_2960512_+	hypothetical protein	NA	NA	NA	NA
WP_077200622.1\|2960532_2960646_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_015296889.1\|2960709_2961009_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_005442033.1\|2961016_2961259_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_077201264.1\|2961333_2961462_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410842.1\|2961501_2962284_+	hypothetical protein	NA	NA	NA	NA
WP_158652677.1\|2962447_2963413_+	hypothetical protein	NA	NA	NA	NA
WP_103410833.1\|2963438_2964407_-\|transposase	IS30-like element ISVa6 family transposase	W5R8L2	Staphylococcus_phage	3.3e-43	37.5
WP_080540787.1\|2964871_2965486_+	HNH endonuclease	NA	NA	NA	NA
WP_103410844.1\|2965454_2965592_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410845.1\|2965618_2965921_+	hypothetical protein	NA	NA	NA	NA
WP_103410846.1\|2965917_2966028_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410847.1\|2966624_2967119_+	hypothetical protein	NA	NA	NA	NA
WP_077200625.1\|2967840_2968329_+	hypothetical protein	NA	NA	NA	NA
WP_103410848.1\|2968315_2968447_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410392.1\|2968702_2969746_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_077201266.1\|2970444_2970561_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_103410850.1\|2970671_2971190_+	hypothetical protein	NA	NA	NA	NA
WP_103410851.1\|2971182_2971599_+	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|2971624_2972420_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_077200630.1\|2972623_2973034_+	hypothetical protein	NA	NA	NA	NA
WP_158652678.1\|2973806_2974298_+	hypothetical protein	NA	NA	NA	NA
WP_045419322.1\|2974664_2974937_+	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|2975083_2975879_+\|transposase	IS5 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP026317

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP026317_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026317_1

27529-28091

TypeI-E

Consensus_repeat	Method
AGAAACATCCACGATTACGTGGAAAATAC	CRISPRCasFinder

9 spacers

cas5,cas7,cas6e,cse2gr11,cas8e

The CRISPR arrays of NZ_CP026317_1

>merge|NZ_CP026317|1|27529-28091|CRISPRCasFinder
GTAAACATCCACGCTAGTGTGGAAAAGACTCATTCAGCAACCAACTTCATTACGTCTGAAGAAACATCCACGCTTGCGTGGAAAATACAGAATACACATCTCTTTTATCATACCACTATTGGAAACATCCACGATTTCCGTGGAAAATAATTTGCTGCGTAACATTGAACTGTCTTGTAGGAAGAAACATCCACGCTTGCGTGGAAAAGACTAATTTTTAATCTGGAATGTCTTTAACCTTGAGAAACATCCACGGTTACGTGGAAAAGACTCTCGGCAATAACAATGTTAGAAACATCCACGATTACGTGGAAAATACAATGCTGAGGTTGGTAAATTGCCATTTCAATCAGAAACATCCACGACTACGTGGAAAATACGTGGTTGTAACGAATCTGAACCTTTTGATTCTGGAAACATCCACGCGAGCGTGGGAAATACCATGAGTCTACGTGACCGATTTGCATCCACTGAGAAACATCCACGACTACGTGGGAAATACCTCTGTCCGTTGAGCATCCACTGCAGTCTTCCAGAAACATCCACGATTACGTGGGAAATAC

>NZ_CP026317|1|1|27529-28091|CRISPRCasFinder
GTAAACATCCACGCTAGTGTGGAAAAGAC	TCATTCAGCAACCAACTTCATTACGTCTGA
AGAAACATCCACGCTTGCGTGGAAAATAC	AGAATACACATCTCTTTTATCATACCACTATT
GGAAACATCCACGATTTCCGTGGAAAATA	ATTTGCTGCGTAACATTGAACTGTCTTGTAGGA
AGAAACATCCACGCTTGCGTGGAAAAGAC	TAATTTTTAATCTGGAATGTCTTTAACCTTG
AGAAACATCCACGGTTACGTGGAAAAGAC	TCTCGGCAATAACAATGTT
AGAAACATCCACGATTACGTGGAAAATAC	AATGCTGAGGTTGGTAAATTGCCATTTCAATC
AGAAACATCCACGACTACGTGGAAAATAC	GTGGTTGTAACGAATCTGAACCTTTTGATTCT
GGAAACATCCACGCGAGCGTGGGAAATAC	CATGAGTCTACGTGACCGATTTGCATCCACTG
AGAAACATCCACGACTACGTGGGAAATAC	CTCTGTCCGTTGAGCATCCACTGCAGTCTTCC
AGAAACATCCACGATTACGTGGGAAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026317.1\|WP_103412102.1\|17469_18000_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|349760
NZ_CP026317.1\|WP_103412112.1\|33048_34080_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP026317.1\|WP_103410819.1\|20948_22478_+\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP026317.1\|WP_103412113.1\|34091_34721_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|187858
NZ_CP026317.1\|WP_158652715.1\|31327_31741_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_158652709.1\|18050_18311_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412109.1\|30944_31331_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_158652717.1\|34720_35245_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP026317.1\|WP_158652713.1\|27108_27498_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214947
NZ_CP026317.1\|WP_103411034.1\|19024_20269_+\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NZ_CP026317.1\|WP_158652711.1\|26665_26962_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131433
NZ_CP026317.1\|WP_103411034.1\|29288_30533_+\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NZ_CP026317.1\|WP_103412104.1\|22847_23864_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP026317.1\|WP_103410057.1\|20535_20889_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NZ_CP026317.1\|WP_103412111.1\|32350_33052_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|273842
NZ_CP026317.1\|WP_103412115.1\|35231_36767_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
NZ_CP026317.1\|WP_103411033.1\|18700_19006_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412108.1\|28434_28821_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412105.1\|23860_25237_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP026317.1\|WP_103411033.1\|28964_29270_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP026317.1\|WP_103412102.1\|17469_18000_-\|AAA-family-ATPase	gnl\|CDD\|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	1.83027e-06
NZ_CP026317.1\|WP_158652717.1\|34720_35245_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	3.70668e-16
NZ_CP026317.1\|WP_103410819.1\|20948_22478_+\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.07949e-123
NZ_CP026317.1\|WP_103412105.1\|23860_25237_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	9.69758e-100
NZ_CP026317.1\|WP_103412112.1\|33048_34080_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	3.45604e-108
NZ_CP026317.1\|WP_158652713.1\|27108_27498_+\|hypothetical-protein	gnl\|CDD\|214947	smart00974, T5orf172, This entry represents the putative helicase A859L.	0.000683315
NZ_CP026317.1\|WP_103411034.1\|19024_20269_+\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	1.28051e-62
NZ_CP026317.1\|WP_158652711.1\|26665_26962_+\|hypothetical-protein	gnl\|CDD\|131433	TIGR02380, ECA_wecA, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. Members of this family are the WecA enzyme of enterobacterial common antigen biosynthesis, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. This family represents one narrow clade, and closely related sequences outside this clade may represent enzymes that catalyze the same specific reaction, but in the context of different pathways. A His-rich motif in a cytosolic loop of this integral membrane protein, shown critical to enzymatic activity for WecA is variously present or absent in the clade that includes Bacillus subtilis TagO teichoic acid biosynthesis enzyme, which may catalyze the same reaction as WecA. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	6.1496e-05
NZ_CP026317.1\|WP_103412104.1\|22847_23864_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	2.4007e-62
NZ_CP026317.1\|WP_103410057.1\|20535_20889_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	3.27798e-38
NZ_CP026317.1\|WP_103412111.1\|32350_33052_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	1.04668e-51
NZ_CP026317.1\|WP_103412115.1\|35231_36767_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	5.60145e-49
NZ_CP026317.1\|WP_103411034.1\|29288_30533_+\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	1.28051e-62
NZ_CP026317.1\|WP_103412113.1\|34091_34721_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	8.25609e-44

>NZ_CP026317.1|WP_158652713.1|27108_27498_+|hypothetical-protein
MYKESIISFGVLVFCMILLVKSRRKKFKKPEGKIYVIYPKSNKWICKVGLTKRDAHRRVAELNDQCYFGKSDWNVYKTYEVSDIKQAEDDCHSILLRHQLIGKKNEKEVFSLHPFIAVMKIRNTLKIYR
>NZ_CP026317.1|WP_158652711.1|26665_26962_+|hypothetical-protein
MKPSTIYWLVPIPLFDFSCTLLKRFLDNTDKDNIIVSLKKFGFSDHVSGVILGVMSLVYMSVGVIGDSVDADPTLMGLALCIAFMVHWCVVDDLRLKD
>NZ_CP026317.1|WP_103412105.1|23860_25237_-|HlyC/CorC-family-transporter
MIEPLLTFLFGILLILAIIAANGYFVAQEFAYMAVDRTRLVTFAASGDAAAKRALSVTNRTSFMLSGAQLGITVTGLVLGFVAEPLVGRSIGVLLQNFGIELEIGIAIGTVATLVIAMVVQMILGELYPKNLAIANAEPMSRMLSRSTLIYMSVFGWFISFFDKSANLLLRAVRIEPVHDLDVSASEGDLHHIIANSRNSGDLPVELSFMMDRILDFPERDVEHAMVPRSQVDWVVPETTLTELLSLMAQAHTRYPVINDDDAPVGVVHLADVLKKIETGHADATVSSVMRPATVLPTLMRLPDALDQLVTSTNQLACVIDEYGGFAGVLTIEDLAMEIVGEITDEHDMDNSNAVVAESDKVWLMTGDVHLDEVKRAIGYDLPRRDVETIAGMLIAEKGALPTNGEMITVALPIDPSELASGEPLLRHLEVSVLRIERHVPTEVRVKLVEKSILEKKK
>NZ_CP026317.1|WP_103412104.1|22847_23864_-|HlyC/CorC-family-transporter
MNDPLIVFIITFALIVLSGIFVIIEFALLGARRHRLEEIAVESRSARAALRGMNDLTLMLAGAQLGITFCTFALGAVTKPAVDQWVGPVFISMGMSEWLADGASFGFALFVVTFLHLVVGEMAPKSWSIAHPEKSALAIGIVARAYVWPLRPLLNWINSIANRLVKASGVEPVESAAVGGQDIDTIRHLVEHSGKVGTLQPKIQKQLSGLIDLSSIQIDSLVTEGQVMAHVDKNATVADVRAAAMESGHLRILVFGKSGLKPLVVHVRDTLLEPSERPAREVARNAYVLDSKTPVYEALVRMREASVQLAVVSKDEKMVGIVTLADILKRVLPPTSLN
>NZ_CP026317.1|WP_103410819.1|20948_22478_+|IS66-family-transposase
MKKTPNINPESQDIAELQAMVKALMASENRLKQERQSLLEQLKLAFERQFAKRSEALKPYDESQGDLFNEVECEATKEEEVEVTTTTTTKKRGKRKPLPKTLPREVIELDLDDHEKQCACCKHSLHKIGEDRSEKLEFSPAVLKVLEYVRPKYACRQCEQTEDKNRIVQKPAPQSIIPKSFATESLLANIILGKYQYAMPLYRQESLFTQSGIELSRTTMARWVIQVSEKFKPLYAALKEHLLQQVVVQADETPLNVLKEDKQCYMWLYCSGADSPDAALPDVKNIALYDYQNSRARACPVAFLGDYSGYLQTDGYGAYDGLHQVTNVGCLAHARRKFMEAKKLQGKGKSGKADKALAKIQKLYGIESRLKGATVETRKAERQLHAKPILDELHEWMTTQKVISSSPLGKAIKYTLGQWPKLIRYIDDGHLSIDNNRAERAIKPLVIGRKNWLFSNTPNGADASAMLYSIVETAKANGLILYDYMVKCMKELAKAEPDVDALLPWNFKH
>NZ_CP026317.1|WP_103410057.1|20535_20889_+|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MKRMLSAPEIYLYRESVDFRKSINGLAAIIESDTDLLLGSGALFLFTNKQRDKIKVLYWDKTGFALWYKRLEKAKYKWPTKEKNEVFTLTQFELDRLLSGFTIIGHKPVRINDFTMT
>NZ_CP026317.1|WP_103411034.1|19024_20269_+|IS91-family-transposase
MVQYSSRRRRHTPNEFVPRATKLLFEKDNAWEKVLWKHAQTFSLWQITCVERMLACGSNMMGAKHYDCGTPNCPHTKVICQSCKTKACSSCGTKSTEQWISTQLDVMPDCEHQHITFTMPSELWPIFEANPKLLNDLFSLAADTLLKWAKKYGLEVGIFGALHTYGRGLNWHPHIHLSVTRGGLDKHNIWRPIYFKKKHVEYHWRRCLIGLLRRKYSELNLSTLSTNHIQDSRQWHFFLERQYQRYWNIHFAQKTQELKQTVNYLGRYLKRPPISASRLRHYSGGTVVFKYLDHRDGKYKTKTLTQEEMILRYVSHLPQHHFKMVRYYGFLSNRKRGRLLPLVYLALGEKSPKQAEPLTYAKQYKGFTGNDPYQCVLCGSRMVFTGFRAGSKNRELLDNRRMSMRESRRLGVPA
>NZ_CP026317.1|WP_103411033.1|18700_19006_+|hypothetical-protein
MKKVKLGFYDVKFGSVALCHGVSLVVTHDKSTLRELAPVNKGHVYQTVYLHHVLDGLALGAEYDFDTPAFNVLKEHIELNEFSHHALDEAEPTFHRVKLAN
>NZ_CP026317.1|WP_158652709.1|18050_18311_-|hypothetical-protein
MDSVSEPSDFKSLKIRTSTGVYVMCKFDNSLTVGHDKTISESIDYAMVTFDPDLLKEVVVDVDLSFVSESIIKMLHKTHPATLKIT
>NZ_CP026317.1|WP_103412102.1|17469_18000_-|AAA-family-ATPase
MKVICLIGSKGGVGKSTLVNYIAWVLRTVYKKKVSVCNLDFQNHVQVVNHDDADFLIFDTVGAYAERTTNLLNKLKNDPNATVICPMGTGINDRKEYRFTVDQMMKYGLLDKTTFVMNKARQGSKSLADSRSLLKEMDVKVSVASVSILEDYAQERYTSRTKNEISRVLNEILGRL
>NZ_CP026317.1|WP_103412108.1|28434_28821_-|hypothetical-protein
MKSNFAFRNTPPEPTVDVPLGSGKIEIETQKIYQIKVEPTMVSHLGNKAITDEIRWHATNEEMTTNFLMTTGAGTLETYRIAPDSDNLTSVRFYPRIYTSSVNSVSDVLNAYGSVRSEIDLTVTCIPE
>NZ_CP026317.1|WP_103411033.1|28964_29270_+|hypothetical-protein
MKKVKLGFYDVKFGSVALCHGVSLVVTHDKSTLRELAPVNKGHVYQTVYLHHVLDGLALGAEYDFDTPAFNVLKEHIELNEFSHHALDEAEPTFHRVKLAN
>NZ_CP026317.1|WP_103411034.1|29288_30533_+|IS91-family-transposase
MVQYSSRRRRHTPNEFVPRATKLLFEKDNAWEKVLWKHAQTFSLWQITCVERMLACGSNMMGAKHYDCGTPNCPHTKVICQSCKTKACSSCGTKSTEQWISTQLDVMPDCEHQHITFTMPSELWPIFEANPKLLNDLFSLAADTLLKWAKKYGLEVGIFGALHTYGRGLNWHPHIHLSVTRGGLDKHNIWRPIYFKKKHVEYHWRRCLIGLLRRKYSELNLSTLSTNHIQDSRQWHFFLERQYQRYWNIHFAQKTQELKQTVNYLGRYLKRPPISASRLRHYSGGTVVFKYLDHRDGKYKTKTLTQEEMILRYVSHLPQHHFKMVRYYGFLSNRKRGRLLPLVYLALGEKSPKQAEPLTYAKQYKGFTGNDPYQCVLCGSRMVFTGFRAGSKNRELLDNRRMSMRESRRLGVPA
>NZ_CP026317.1|WP_103412109.1|30944_31331_-|hypothetical-protein
MKRLVLISLLLSANAFAGINQSVRSNDLDCFVDVDDPFEMYVEGVNSQYNSDNDDHNNYWNNNYRDDKQVRIGIKYKFGSGIKPIDCDSLFQVELRKKEIELERLRSALENMKALDSLQSLGNELPAL
>NZ_CP026317.1|WP_158652715.1|31327_31741_-|hypothetical-protein
MNKTLLTTISSSLVVFSGAGFSHGHHPSIHKEYLTSTHGILKITLLNGYENRMCYQFEQDGKELTPLQVCLDGKEQRELDFDVIVEPDVKKEFTFCSLSGFIGDSSRVRSRMCTEVSMLYAKTLIEKRQKQLEELRK
>NZ_CP026317.1|WP_103412111.1|32350_33052_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSNPYVLMWLESPIQSWGYDSRFGRRDTLLFPTKSGVLGIICNALGREGEQSDFLSEFIELDIQVYAFPRSVDGMIKNLPMLKDFHMVGSGYDDKDPWELLHIPKTSEGKKVVGGGSKMTYRYYLQDMAFAVLLEIPSKRVSEIIESLQFPVYDLCLGRKCCVPTEFVYQGVFDVADEGVSVATKLATSKSRKLHFVVTEGGGEGEQLTISDVPIRFGSYKQYQDRIVTIRYE
>NZ_CP026317.1|WP_103412112.1|33048_34080_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MKTTRIEFHILQSFPVTCLNRDDIGSPKSAIVGGVPRARVSSQCWKRQVRMSMRDFGIKIGTRTKKIEKLMNGACLSLDAEIKEAQLCADVIAKELSSETLVFISDTECKAFAEYAKSLNFDHTKIKSKELGKISKKVINPAIDALDIALFGRMVAKSSEMDVQAACSFNHAISTHKAVNEIEFFTALDDIRMDGEQGSGHMGSIEFNSATYYRYISLDIGRLAASMNPNDVKTAIEAFTKALFVAVPNARQTTQSGASPWEYAKVLVRKGQGLQVPFEVPVQCENGSYLKPSIDAMNKYLDDKEALFGSIFGKLGCYEWGVDTSYNIDSLINDLKTHVTYNL
>NZ_CP026317.1|WP_103412113.1|34091_34721_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MQLYASVLKIDRKSFKELRIKDTYSLHRVVYNLFECVDNETSRCIQWVDMGGDFHSRDVLIFSDKIPRSSIDGAGTVVTKEIPLQFLGYDFYRFEIVVNPSYRPMKRGSELNGNRTKIVPIKGRENIEKWFIEKSVKCGFECSAIQVESVVVDKFNAKSSVTIQKVKIVGQLKVTDRDQFIKTVASGIGRAKGFGCGLLQVTPIIESLF
>NZ_CP026317.1|WP_158652717.1|34720_35245_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTKYERCYSFVDYVKLNCRTNKRFASSLNHADYQSGTESNIWDLLCRFDVDIENDNERIPFILIGAAIARGDNHNIHTLPLGRAIYKSFPNGDEQGSARLRRLISCDTTEEVCNVLRPLLGLLQSKIKISINYAELLCQLIEYSNNPESVRMIWTNDFYRFRPEEESSSQKGEA
>NZ_CP026317.1|WP_103412115.1|35231_36767_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNHFNLIEESWIPVAGVGLVSLRDVFNDHTLKSLGGTPIEKIALTKLLVAIAQSAYTPEDFCEWSSLGSSGLSSKCLSYLEYNKNRFYLYGDNPFLQFHEVKDIARYSTKGKKEKLLPYGALIPEVATGNTTRLTGYNIERSLTDGQKALILITQLSMCFSGKKADNSIVLTEGYEGKSNDKGKPSTPRSGTGIAHMGLLHSFAHGSSLQETIWLNVFTNQDIQETNMFQLGVGVAPWEQMPKGEDCAVARRLKSTLMGRLVPMCRFMYLEKNGVYITEGIHHLTHKDHMFDPSITVKPTCKTRSELKVVWTDPDRKPWRQLPSMLGFLSGSPDMCYQLKFAFDKAKRANRLISVWSGGAQVSANAGEQYLSGGNDTVETIMSIPYESHNHMGFIKYTNEIKELDAISKRLYGCVLGYASEFNKDGKDIALNATMMFWEACGHNAQLLIDSCFDETSESYEKIYQLRKVFFDNVQTIYDILCANHSSRQMQAWSKCRPNAWKYLERSYDEI

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Crispr_ID: NZ_CP026317_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026317_2

107107-107217

Orphan

Consensus_repeat	Method
AAAACAAGATTTTACACGAGACATGGAAAAACTGGGGTTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP026317_2

>merge|NZ_CP026317|2|107107-107217|CRISPRCasFinder
AAAACAAGATTTTACACGAGACATGGAAAAACTGGGGTTTGGCTAGGTTCGTTACTATCCTTTGACTGAAAAACAGGATTTTACACGAGACATGGAAAAACTGGGGTTTGG

>NZ_CP026317|2|2|107107-107217|CRISPRCasFinder
AAAACAAGATTTTACACGAGACATGGAAAAACTGGGGTTTGG	CTAGGTTCGTTACTATCCTTTGACTGA
AAAACAGGATTTTACACGAGACATGGAAAAACTGGGGTTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026317.1\|WP_086028371.1\|120326_121123_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP026317.1\|WP_103412151.1\|101897_102866_-\|ParM/StbA-family-protein	unknown	unknown	gnl\|CDD\|212669
NZ_CP026317.1\|WP_103411033.1\|100440_100746_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412148.1\|100820_101030_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412156.1\|110125_110389_-\|Txe/YoeB-family-addiction-module-toxin	unknown	unknown	gnl\|CDD\|284238
NZ_CP026317.1\|WP_103411034.1\|105405_106650_-\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NZ_CP026317.1\|WP_086028371.1\|124260_125057_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP026317.1\|WP_103412157.1\|110381_110636_-\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	unknown	unknown	gnl\|CDD\|171099
NZ_CP026317.1\|WP_103412155.1\|109473_110082_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103411033.1\|106668_106974_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412161.1\|122122_123361_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP026317.1\|WP_103410155.1\|103679_105212_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP026317.1\|WP_103412184.1\|107510_108491_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|290455
NZ_CP026317.1\|WP_103412152.1\|103201_103627_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103411034.1\|99177_100422_-\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NZ_CP026317.1\|WP_103412160.1\|114731_119501_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412150.1\|101483_101894_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026317.1\|WP_103412153.1\|108510_108879_-\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|276807
NZ_CP026317.1\|WP_103412184.1\|112351_113332_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|290455
NZ_CP026317.1\|WP_103412147.1\|97837_98764_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP026317.1\|WP_086028371.1\|120326_121123_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.96956e-25
NZ_CP026317.1\|WP_103412151.1\|101897_102866_-\|ParM/StbA-family-protein	gnl\|CDD\|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	2.8487e-34
NZ_CP026317.1\|WP_103412184.1\|112351_113332_+\|IS5-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	2.75258e-24
NZ_CP026317.1\|WP_103412156.1\|110125_110389_-\|Txe/YoeB-family-addiction-module-toxin	gnl\|CDD\|284238	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system. YoeB_toxin is a family of bacterial toxins that forms one component of the type II toxin-antitoxin system in E. coli whose antitoxin is represented by YefM, found in pfam02604. The plasmid encoded Axe-Txe proteins in Enterococcus faecium act as an antitoxin-toxin pair. When the plasmid is lost, the antitoxin is degraded relatively quickly by host enzymes. This allows the toxin to interact with its intracellular target, thus killing the cell or impeding cell growth. These toxins are highly potent protein synthesis inhibitors, specifically blocking the initiation of translation. In the case of YoeB, it binds to the 50 S ribosomal subunit in 70 S ribosomes and interacts with the A site leading to mRNA cleavage at this site. As a result, the 3'-end portion of the mRNA is released from ribosomes, and translation initiation is effectively inhibited.	5.21832e-48
NZ_CP026317.1\|WP_103411034.1\|105405_106650_-\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	1.28051e-62
NZ_CP026317.1\|WP_086028371.1\|124260_125057_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.96956e-25
NZ_CP026317.1\|WP_103412157.1\|110381_110636_-\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	gnl\|CDD\|171099	PRK11409, PRK11409, YoeB-YefM toxin-antitoxin system antitoxin YefM.	7.235e-22
NZ_CP026317.1\|WP_103412161.1\|122122_123361_-\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	5.32618e-68
NZ_CP026317.1\|WP_103410155.1\|103679_105212_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	2.18958e-124
NZ_CP026317.1\|WP_103412184.1\|107510_108491_+\|IS5-family-transposase	gnl\|CDD\|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	2.75258e-24
NZ_CP026317.1\|WP_103411034.1\|99177_100422_-\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	1.28051e-62
NZ_CP026317.1\|WP_103412153.1\|108510_108879_-\|sel1-repeat-family-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	7.61585e-20

>NZ_CP026317.1|WP_103411033.1|106668_106974_-|hypothetical-protein
MKKVKLGFYDVKFGSVALCHGVSLVVTHDKSTLRELAPVNKGHVYQTVYLHHVLDGLALGAEYDFDTPAFNVLKEHIELNEFSHHALDEAEPTFHRVKLAN
>NZ_CP026317.1|WP_103411034.1|105405_106650_-|IS91-family-transposase
MVQYSSRRRRHTPNEFVPRATKLLFEKDNAWEKVLWKHAQTFSLWQITCVERMLACGSNMMGAKHYDCGTPNCPHTKVICQSCKTKACSSCGTKSTEQWISTQLDVMPDCEHQHITFTMPSELWPIFEANPKLLNDLFSLAADTLLKWAKKYGLEVGIFGALHTYGRGLNWHPHIHLSVTRGGLDKHNIWRPIYFKKKHVEYHWRRCLIGLLRRKYSELNLSTLSTNHIQDSRQWHFFLERQYQRYWNIHFAQKTQELKQTVNYLGRYLKRPPISASRLRHYSGGTVVFKYLDHRDGKYKTKTLTQEEMILRYVSHLPQHHFKMVRYYGFLSNRKRGRLLPLVYLALGEKSPKQAEPLTYAKQYKGFTGNDPYQCVLCGSRMVFTGFRAGSKNRELLDNRRMSMRESRRLGVPA
>NZ_CP026317.1|WP_103410155.1|103679_105212_-|IS66-family-transposase
MKKTPVINPESQDVAELQAMVKTLLASESQWKQERQSLLEQLKLAFDRQFAKRSEALKPYDESQGDLFNEVECEAAKEEEVEVVTTTTTTKKRGKRKPLPKTLPREVIELDLDDHEKQCACCQHSLHKIGEDRSEKLEFSPAVLKVLEYVRPKYACRQCEQTEDKSHIVQKPAPQSIIPKSFATESLLANIILGKYQYAMPLYRQESLFTQSGIELSRSTMARWVIQVSEKFKPLYAALKEHLLQQVVVQADETPLNVLKEDKQCYMWLYCSGADSPDAALPNVKNIALYDYQNSRARACPVAFLGDYSGYLQTDGYGAYDGLHHVTNVGCLAHARRKFMDAKKLQGKGKSGKADKALAKIQKLYGIESRLKGATVETRKAERQQHAKPILDELHDWMTSQQVISSSPLGKALKYTLGQWPKLIRYIDDGHLSIDNNRAERAIKPLVIGRKNWLFSNTPNGADASAMLYSIVETAKANGLILYDYMVKCMKELAKAEPDIDALLPWNFKH
>NZ_CP026317.1|WP_103412152.1|103201_103627_+|hypothetical-protein
MSVKCIKNYGFEHQGLSQVIPFFIVDDVIVNYAFVCDDKSFKTPVGKIKKACLMSILNAEYVSVFVPNGSFDDMKKTIRDEFTKTHKGGVAKLAILFEIQSTGAASDSTFYEGLGIVPNEAEYITFEQSGLKSSGHPFRCF
>NZ_CP026317.1|WP_103412151.1|101897_102866_-|ParM/StbA-family-protein
MNHLNVEVIDKASIDDGSSAIKAAFDKGDGVKTHSFESRVIRNALPDNKTVTGFSASSYEINGEKYAVVEDSDGIVPTTTVTYQTSEVNRVLVHHMLKQIGMTGKVSVLVTLPVDQFLNSDGSRNQQLIEAKIANIKGEITYLDGTKPAEIVSVIVVPEGVPAYQYACSELSLGGESNIGRYFVIDIGGTTTDILDIKNGQIVSSGSLPIGALEMIESFKGVIKNRLGFRSVPDSDALEGILTGRTLHNDFSSEAKIEIEKFNKRLSDHVLTDGQYVKYTNVIYSGGGANLVEPEMHNAVKTSNPRFDNALGGLQILQSIGD
>NZ_CP026317.1|WP_103412150.1|101483_101894_-|hypothetical-protein
MANAKSVQIRLREDFPLEKKIIEYLAKIGGRSGLEKQIFVRAMTEHMAENPLDDDIGYAPKNKTKDEKVFKVKPEESKEVVSVEERREPLQEQSSSEGYSSYFGDTQVNPEKVDTQPTPKITPKLTDVASFMYAKG
>NZ_CP026317.1|WP_103412148.1|100820_101030_-|hypothetical-protein
MYSADKIEFNKVIYDYTVLVESGATPYVHSKLTKQHLTGLLSNNLALESIYIALMFSKIAILRIEQGRY
>NZ_CP026317.1|WP_103411033.1|100440_100746_-|hypothetical-protein
MKKVKLGFYDVKFGSVALCHGVSLVVTHDKSTLRELAPVNKGHVYQTVYLHHVLDGLALGAEYDFDTPAFNVLKEHIELNEFSHHALDEAEPTFHRVKLAN
>NZ_CP026317.1|WP_103411034.1|99177_100422_-|IS91-family-transposase
MVQYSSRRRRHTPNEFVPRATKLLFEKDNAWEKVLWKHAQTFSLWQITCVERMLACGSNMMGAKHYDCGTPNCPHTKVICQSCKTKACSSCGTKSTEQWISTQLDVMPDCEHQHITFTMPSELWPIFEANPKLLNDLFSLAADTLLKWAKKYGLEVGIFGALHTYGRGLNWHPHIHLSVTRGGLDKHNIWRPIYFKKKHVEYHWRRCLIGLLRRKYSELNLSTLSTNHIQDSRQWHFFLERQYQRYWNIHFAQKTQELKQTVNYLGRYLKRPPISASRLRHYSGGTVVFKYLDHRDGKYKTKTLTQEEMILRYVSHLPQHHFKMVRYYGFLSNRKRGRLLPLVYLALGEKSPKQAEPLTYAKQYKGFTGNDPYQCVLCGSRMVFTGFRAGSKNRELLDNRRMSMRESRRLGVPA
>NZ_CP026317.1|WP_103412147.1|97837_98764_-|hypothetical-protein
MKHSILAITVLSTIAFGISAKEKINVELLGETAYGFEYSDKAQGVKDISKLDFGVSVSYDNAYAMVFGESGTMTSKGYGHGVDGYGIIMNRVFMGYNINNNVSVQIGSMDSALDLVKDYGNKTVEYSHNATTVEDVRLAVGAFGTVSSIDYGLTVNSEKSGYDGYQAGWNDASALSAYAKTKLGQNTSILGGFEYRMGDETSAVMMGAIDFGLVGANIYHDTKTDATGGSLSIGTKVLKSVYAATGYNFETGSNVVDSMTKLPVEDLSYINAGILWQQTDHFVLKADAKFDLSNQDDHKFWVRQTYTF
>NZ_CP026317.1|WP_103412184.1|107510_108491_+|IS5-family-transposase
MPNKYNQRKRRHFSKPKFRTRNWRQYNQSLKDRGSIDIWLSKEILDEWQFDKRHYDGTGSTVKYPDKTIEACHHLRMVFKQPLRQAQGFIGSLLKMLGRKNLQCPDYSVLSRRLGDLGLVTPRFKQLDIIDKDIVAIAIDSTGLKLYGKDEWHQEKHNIDAKRSWKKAHFVVRNNHIIESAVMTGKDVMDDQVVGDLCQQIIADVKHITADKMYDTNAVYSTLEECFPNADIVIPPKDNSFADEHHNKKRMQNLVSCTALGVMGWQKKRDYGRRNVSETAMQRYKKIIGNRLYSRKSSNQAQEMLIGCSILNRFTQLGMPNSYRVA
>NZ_CP026317.1|WP_103412153.1|108510_108879_-|sel1-repeat-family-protein
MMIPDEIIKKAESGDVESQYNLAWLYDEENNIDEAKKWFEAASNNGHKESQYNLGLLFEELDQLPEAKKWFLEAANQNCSDAQFKLGCLAELEADIESAKNWYKLSAGQGDFDAERLCCNTK
>NZ_CP026317.1|WP_103412155.1|109473_110082_-|hypothetical-protein
MIKITEYFEDFDSAMFHLKSQLNGVVNRGVDTNGNECFVWTGEVDIYYLASKIRSLLSSRDPITEQDKMRFANIGISTLSKPKVSKSGITYLQCNDIISKNIDEAQYKVKRYNQLGLHGDGWRIPTFREIQELDLVFGTWWCTDEHEEVNVYTLDREYGVAFDVETKAVVAIKFQDSKHINGTSNFEGGGYNYSPRVILVRN
>NZ_CP026317.1|WP_103412156.1|110125_110389_-|Txe/YoeB-family-addiction-module-toxin
MSSRLLSWTNEAWDDYLYWQSQDKKTLKRVNKLISDAKRSPFEGIGKPEPLRENLSGFWSRRIDDVNRLVYAVNDESLTIISCRYHY
>NZ_CP026317.1|WP_103412157.1|110381_110636_-|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin
MRIVSFTEARNNLKTILDTVVDDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPNNAEHLNRSIEQYRSGHTTARDLIDE
>NZ_CP026317.1|WP_103412184.1|112351_113332_+|IS5-family-transposase
MPNKYNQRKRRHFSKPKFRTRNWRQYNQSLKDRGSIDIWLSKEILDEWQFDKRHYDGTGSTVKYPDKTIEACHHLRMVFKQPLRQAQGFIGSLLKMLGRKNLQCPDYSVLSRRLGDLGLVTPRFKQLDIIDKDIVAIAIDSTGLKLYGKDEWHQEKHNIDAKRSWKKAHFVVRNNHIIESAVMTGKDVMDDQVVGDLCQQIIADVKHITADKMYDTNAVYSTLEECFPNADIVIPPKDNSFADEHHNKKRMQNLVSCTALGVMGWQKKRDYGRRNVSETAMQRYKKIIGNRLYSRKSSNQAQEMLIGCSILNRFTQLGMPNSYRVA
>NZ_CP026317.1|WP_103412160.1|114731_119501_-|hypothetical-protein
MKRLLLPLCLSIAGCNDYEEYITENNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVSNPSWVSIQDNIISIAPSSANAGNHVFKVKVSDGVLTAEVDAALVVNLPMTPVDPDLVNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVSNPSWVSIQDNIISIAPSSANAGNHVFKVKVSDGVLTAEVDAALVVNLPMTPVDPDLVNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVSNPSWVSIQDNIISIAPSSANAGNHVFKVKVSDGVLTAEVDAALVVNLPMTPVDPDLVNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVNNPSWVSIQDNIISIAPSSANAGNHVFKVKVSDGVLTAEVDAALVVNLPMTPVDPDLVNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVSNPSWVSIQDNIISIAPSSANAGNHVFKVKVSDGVLTAEVDAALVVNLPMTPVDPDLVNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVNNPSWVSIQDNIISIAPSSANAGNHVFKVKVSDGVLTAEVDAALVVNLPMTPVDPDLVNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVNNPSWVSIQDNIISIAPSSANAGNHVFKVKVSDGVLTAEVDAALVVNLPMTPVDPDLVNHAPTIEALSTIKAVAGKTTKVSVTASDKDGDTLTYSLVNNPSWVSIQDNIISMTPSPLDEGVAEFLVIVSDGMLSTRRKVIVDVFVETIVLSATKNSENKRNVELAWEAKPRKHEYQIYRNETLIDKVSSESYDDVMPLSTTSYSYKIKACDADNHCEIESNVKQLRAEPDKIFVKVQGLDTTVESNKAVLQFYYRSTSKLWVSANFSFNKNETRHIIDLGFDTRYMKRMSLQPINGQICSTDKLNVAQFSNGNDVHAVYSCQTAATLVAEMTTVTIQKGSINQVGSPLILSRQSDGANMTSNDYIYESSNPSVVNVNKQGLLSGVSVGESTITVTANPDNYGEQASTSYKVIVDESTHYIMNKMDFGQQLLLPQNNEHQVITAGVEFLVRGFPVALDISNTKKPNLTFIAEVDGIIREYQVFCPEQLPLSISDDTNYTLSDSCYAYIQPDAVSKGGSYYFKDLDSDAKFFISPSINKPSHLKLVIVPLVVNEVAPIIPDLELIKARILETMPIKSVDISIRAPYVYSEPMATHDLGAFLSTVNNIRQREDNSGTHYMGILTGVCGVNGLAYIGSWHSAVIKDERCGGVNAINVSLIHELGHNLSLKHAPCGGASGADSFWTKDPQPWVGARNGAMSDAPIFSLKAQEILIPGSLTTKADIMGYCGGWHFSEYNHRKMALYIENNDVYNIKPDIGMVRSNSKNLVTIVSGKIVNGVVYFDPTSVSTSTRPQEIYQGEYELIVSSDYRYKFDVVKDSNEDILHFNVEIPYTETISSLAIEKNSISYGTKVNVYQRHQMLVNAEVNVSAGHLFVKWDNTDYPWLTAMISNESGSNMLLEEKNTRGYLDAEIPKYFDDNVVTLIFSNGLDTNIQQYCRKDLKYEECN
>NZ_CP026317.1|WP_086028371.1|120326_121123_-|IS5-family-transposase
MSSTQYLISDALWAKIEPLLPIHKTNHPLGTHRKRVDNRDAMNGILFVLRTGCQWNALNATGICTSSSAHRRFQEWRDAGVFERFWQNGLIYEGVDWRSISMDGCQTKAPLAGKKTGKNPTDRAKQGVKRSLLTDANGLPLAVVSDGANVHDIKLVLQTLNALECYRPPLKVPLYLDKGYTGQWLHDELVALNYIPHVQSRAEEAASLKQSDDFKAHRWVVERTHSWLNRYRRLLVRWEKKIENYEAMLHFACGLIVWNKSLLG
>NZ_CP026317.1|WP_103412161.1|122122_123361_-|IS256-family-transposase
MTDNTVVSLNTTQDPLTELIRQGARDLIAQAVEAELQQLLAQYQNTMADGKQAIVRNGFLPERTLQTGIGDVEVQIPKVRDRSGNGVKFNSSLIPPYLKRTKSVETLLPLLYLKGISTGDMLPALESLLGRDAKGLSASSVSRLKEQWSTEYEQWRKRDLGRRRYVYVWADGVYCHVRMDDKLCLLVIIGVDDTGRKEVLGVLDGHRESEASWTELIEQLRVQGLQLAPKLAIGDGALGFWKAVAKCWPQTAQQRCWVHKTTNVLNKVPKSVQPRMKEALQDIWMAETRDDAYHAFSTFQKRFEAKYPKATDCLVKDKAEMLAFYDYPAEHWVHIRTTNPIESMFATVRLRTNKTKNCGNRKTTLMMAYKLMRSAETKWRRLRGFALLADVVKDVRFIDGVKEMETHQQATA
>NZ_CP026317.1|WP_086028371.1|124260_125057_-|IS5-family-transposase
MSSTQYLISDALWAKIEPLLPIHKTNHPLGTHRKRVDNRDAMNGILFVLRTGCQWNALNATGICTSSSAHRRFQEWRDAGVFERFWQNGLIYEGVDWRSISMDGCQTKAPLAGKKTGKNPTDRAKQGVKRSLLTDANGLPLAVVSDGANVHDIKLVLQTLNALECYRPPLKVPLYLDKGYTGQWLHDELVALNYIPHVQSRAEEAASLKQSDDFKAHRWVVERTHSWLNRYRRLLVRWEKKIENYEAMLHFACGLIVWNKSLLG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP026317_1	1.1\|27558\|30\|NZ_CP026317\|CRISPRCasFinder	27558-27587	30	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27558-27587	0	1.0
NZ_CP026317_1	1.2\|27617\|32\|NZ_CP026317\|CRISPRCasFinder	27617-27648	32	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27617-27648	0	1.0
NZ_CP026317_1	1.3\|27678\|33\|NZ_CP026317\|CRISPRCasFinder	27678-27710	33	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27678-27710	0	1.0
NZ_CP026317_1	1.4\|27740\|31\|NZ_CP026317\|CRISPRCasFinder	27740-27770	31	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27740-27770	0	1.0
NZ_CP026317_1	1.5\|27800\|19\|NZ_CP026317\|CRISPRCasFinder	27800-27818	19	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27800-27818	0	1.0
NZ_CP026317_1	1.6\|27848\|32\|NZ_CP026317\|CRISPRCasFinder	27848-27879	32	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27848-27879	0	1.0
NZ_CP026317_1	1.7\|27909\|32\|NZ_CP026317\|CRISPRCasFinder	27909-27940	32	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27909-27940	0	1.0
NZ_CP026317_1	1.8\|27970\|32\|NZ_CP026317\|CRISPRCasFinder	27970-28001	32	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	27970-28001	0	1.0
NZ_CP026317_1	1.9\|28031\|32\|NZ_CP026317\|CRISPRCasFinder	28031-28062	32	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	28031-28062	0	1.0
NZ_CP026317_2	2.1\|107149\|27\|NZ_CP026317\|CRISPRCasFinder	107149-107175	27	NZ_CP026317	Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence	107149-107175	0	1.0
NZ_CP026317_1	1.4\|27740\|31\|NZ_CP026317\|CRISPRCasFinder	27740-27770	31	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	289611-289641	6	0.806
NZ_CP026317_1	1.7\|27909\|32\|NZ_CP026317\|CRISPRCasFinder	27909-27940	32	NZ_CP016481	Synechococcus sp. PCC 7117 plasmid unnamed4, complete sequence	37105-37136	8	0.75
NZ_CP026317_1	1.2\|27617\|32\|NZ_CP026317\|CRISPRCasFinder	27617-27648	32	NZ_CP040241	Campylobacter coli strain S9 plasmid pCcS9_2, complete sequence	1220-1251	9	0.719
NZ_CP026317_1	1.8\|27970\|32\|NZ_CP026317\|CRISPRCasFinder	27970-28001	32	NZ_CP017589	Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ08, complete sequence	3257-3288	9	0.719

1. spacer 1.1|27558|30|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

tcattcagcaaccaacttcattacgtctga	CRISPR spacer
tcattcagcaaccaacttcattacgtctga	Protospacer
******************************

2. spacer 1.2|27617|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

agaatacacatctcttttatcataccactatt	CRISPR spacer
agaatacacatctcttttatcataccactatt	Protospacer
********************************

3. spacer 1.3|27678|33|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

atttgctgcgtaacattgaactgtcttgtagga	CRISPR spacer
atttgctgcgtaacattgaactgtcttgtagga	Protospacer
*********************************

4. spacer 1.4|27740|31|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

taatttttaatctggaatgtctttaaccttg	CRISPR spacer
taatttttaatctggaatgtctttaaccttg	Protospacer
*******************************

5. spacer 1.5|27800|19|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

tctcggcaataacaatgtt	CRISPR spacer
tctcggcaataacaatgtt	Protospacer
*******************

6. spacer 1.6|27848|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

aatgctgaggttggtaaattgccatttcaatc	CRISPR spacer
aatgctgaggttggtaaattgccatttcaatc	Protospacer
********************************

7. spacer 1.7|27909|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

gtggttgtaacgaatctgaaccttttgattct	CRISPR spacer
gtggttgtaacgaatctgaaccttttgattct	Protospacer
********************************

8. spacer 1.8|27970|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

catgagtctacgtgaccgatttgcatccactg	CRISPR spacer
catgagtctacgtgaccgatttgcatccactg	Protospacer
********************************

9. spacer 1.9|28031|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

ctctgtccgttgagcatccactgcagtcttcc	CRISPR spacer
ctctgtccgttgagcatccactgcagtcttcc	Protospacer
********************************

10. spacer 2.1|107149|27|NZ_CP026317|CRISPRCasFinder matches to NZ_CP026317 (Vibrio campbellii strain BoB-90 plasmid unnamed 1, complete sequence) position: , mismatch: 0, identity: 1.0

ctaggttcgttactatcctttgactga	CRISPR spacer
ctaggttcgttactatcctttgactga	Protospacer
***************************

11. spacer 1.4|27740|31|NZ_CP026317|CRISPRCasFinder matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 6, identity: 0.806

taatttttaatctggaatgtctt-taaccttg	CRISPR spacer
taattttgaatcgggaatgtcttattatttt-	Protospacer
******* **** ********** * *..**

12. spacer 1.7|27909|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP016481 (Synechococcus sp. PCC 7117 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

gtggttgtaacgaatctgaaccttttgattct	CRISPR spacer
atattattaacgaatctgaagctttagattcg	Protospacer
.*. *  ************* **** *****

13. spacer 1.2|27617|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP040241 (Campylobacter coli strain S9 plasmid pCcS9_2, complete sequence) position: , mismatch: 9, identity: 0.719

agaatacacatctcttttatcataccactatt	CRISPR spacer
gaattcagtatcttttttatcataccacaatt	Protospacer
..* *  ..****.************** ***

14. spacer 1.8|27970|32|NZ_CP026317|CRISPRCasFinder matches to NZ_CP017589 (Pantoea stewartii subsp. stewartii DC283 plasmid pDSJ08, complete sequence) position: , mismatch: 9, identity: 0.719

catgagtctacgtgaccgatttgcatccactg	CRISPR spacer
ttaaagtctacgtgacggatttgtatccagaa	Protospacer
.  .************ ******.*****  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2205 : 145229

114

Mycobacterium_phage(39.13%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158652704.1\|2205_8352_-\|protease	SslE/AcfD family lipoprotein zinc metalloprotease	NA	NA	NA	NA
WP_103412095.1\|8564_9374_-	hypothetical protein	NA	NA	NA	NA
WP_103412097.1\|9729_12372_-	glycoside hydrolase	A0A097P8Z3	Sucra_jujuba_nucleopolyhedrovirus	1.5e-199	59.5
WP_158652706.1\|13506_14190_+	N-6 DNA methylase	H7BVT3	unidentified_phage	1.8e-11	31.6
WP_086028371.1\|15073_15869_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_158652707.1\|15806_16406_-	hypothetical protein	NA	NA	NA	NA
WP_103412101.1\|17098_17470_-	hypothetical protein	NA	NA	NA	NA
WP_103412102.1\|17469_18000_-	AAA family ATPase	NA	NA	NA	NA
WP_158652709.1\|18050_18311_-	hypothetical protein	NA	NA	NA	NA
WP_103411033.1\|18700_19006_+	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|19024_20269_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103410057.1\|20535_20889_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_103410819.1\|20948_22478_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	3.0e-70	34.2
WP_103412104.1\|22847_23864_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_103412105.1\|23860_25237_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_158652711.1\|26665_26962_+	hypothetical protein	NA	NA	NA	NA
WP_158652713.1\|27108_27498_+	hypothetical protein	NA	NA	NA	NA
WP_103412108.1\|28434_28821_-	hypothetical protein	NA	NA	NA	NA
WP_103411033.1\|28964_29270_+	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|29288_30533_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103412109.1\|30944_31331_-	hypothetical protein	NA	NA	NA	NA
WP_158652715.1\|31327_31741_-	hypothetical protein	NA	NA	NA	NA
WP_103412111.1\|32350_33052_-	type I-E CRISPR-associated protein Cas5/CasD	NA	NA	NA	NA
WP_103412112.1\|33048_34080_-	type I-E CRISPR-associated protein Cas7/Cse4/CasC	NA	NA	NA	NA
WP_103412113.1\|34091_34721_-	type I-E CRISPR-associated protein Cas6/Cse3/CasE	NA	NA	NA	NA
WP_158652717.1\|34720_35245_-	type I-E CRISPR-associated protein Cse2/CasB	NA	NA	NA	NA
WP_103412115.1\|35231_36767_-	type I-E CRISPR-associated protein Cse1/CasA	NA	NA	NA	NA
WP_158652719.1\|37161_37770_-	hypothetical protein	NA	NA	NA	NA
WP_103412116.1\|37790_38297_-	hypothetical protein	NA	NA	NA	NA
WP_103410819.1\|38415_39945_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	3.0e-70	34.2
WP_103410057.1\|40004_40358_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_103410056.1\|40354_40672_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_158652721.1\|40729_40885_+	hypothetical protein	NA	NA	NA	NA
WP_158652723.1\|41384_44288_-	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|44854_46099_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103410153.1\|48857_49169_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_103410154.1\|49165_49519_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_103411033.1\|49881_50187_+	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|50205_51450_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103412118.1\|51687_52947_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103412119.1\|53385_54114_-	hypothetical protein	NA	NA	NA	NA
WP_103412120.1\|54091_54385_-	hypothetical protein	NA	NA	NA	NA
WP_103412121.1\|54446_58325_-	beta/gamma crystallin family protein	NA	NA	NA	NA
WP_103411033.1\|59270_59576_+	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|59594_60839_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103410056.1\|61022_61340_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_103410057.1\|61336_61690_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_103410819.1\|61749_63279_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	3.0e-70	34.2
WP_158652724.1\|63386_63881_+	hypothetical protein	NA	NA	NA	NA
WP_103412123.1\|63922_64561_-	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_103412124.1\|64572_65478_-	DUF979 domain-containing protein	NA	NA	NA	NA
WP_103412125.1\|65471_66152_-	DUF969 domain-containing protein	NA	NA	NA	NA
WP_103412127.1\|66793_67207_-	hypothetical protein	NA	NA	NA	NA
WP_103412129.1\|67998_68274_-	hypothetical protein	NA	NA	NA	NA
WP_103412130.1\|68595_69609_+	porin	NA	NA	NA	NA
WP_103412131.1\|69824_70094_-	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|70633_71430_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_103412132.1\|71493_72228_+	OmpA family protein	NA	NA	NA	NA
WP_103412133.1\|72261_72780_-	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|73869_74665_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_103412135.1\|74741_75668_-	sel1 repeat family protein	NA	NA	NA	NA
WP_086028371.1\|75771_76567_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_103412136.1\|76897_77212_-	hypothetical protein	Q858Q3	Vibrio_phage	3.3e-16	48.2
WP_103411033.1\|77453_77759_+	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|77777_79022_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103412138.1\|79968_80721_-	hypothetical protein	NA	NA	NA	NA
WP_103412139.1\|80766_81213_-	hypothetical protein	NA	NA	NA	NA
WP_103411033.1\|81362_81668_+	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|81686_82931_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103412140.1\|83079_83970_-	hypothetical protein	NA	NA	NA	NA
WP_103412141.1\|84121_86167_-	HTH domain-containing protein	NA	NA	NA	NA
WP_103411034.1\|86903_88148_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103411033.1\|88166_88472_-	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|88742_89987_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103411033.1\|90005_90311_-	hypothetical protein	NA	NA	NA	NA
WP_158652725.1\|90648_91068_+	hypothetical protein	NA	NA	NA	NA
WP_103412143.1\|91276_91711_+	hypothetical protein	NA	NA	NA	NA
WP_103412144.1\|92351_92951_-	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|93487_94732_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103412145.1\|94750_95056_-	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|95326_96571_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103411033.1\|96589_96895_-	hypothetical protein	NA	NA	NA	NA
WP_103412147.1\|97837_98764_-	hypothetical protein	NA	NA	NA	NA
WP_103411034.1\|99177_100422_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103411033.1\|100440_100746_-	hypothetical protein	NA	NA	NA	NA
WP_103412148.1\|100820_101030_-	hypothetical protein	NA	NA	NA	NA
WP_103412150.1\|101483_101894_-	hypothetical protein	NA	NA	NA	NA
WP_103412151.1\|101897_102866_-	ParM/StbA family protein	NA	NA	NA	NA
WP_103412152.1\|103201_103627_+	hypothetical protein	NA	NA	NA	NA
WP_103410155.1\|103679_105212_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	2.3e-70	34.6
WP_103411034.1\|105405_106650_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_103411033.1\|106668_106974_-	hypothetical protein	NA	NA	NA	NA
WP_103412184.1\|107510_108491_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	6.0e-40	33.5
WP_103412153.1\|108510_108879_-	sel1 repeat family protein	NA	NA	NA	NA
WP_103412155.1\|109473_110082_-	hypothetical protein	NA	NA	NA	NA
WP_103412156.1\|110125_110389_-	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_103412157.1\|110381_110636_-	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_103412184.1\|112351_113332_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	6.0e-40	33.5
WP_103412160.1\|114731_119501_-	hypothetical protein	NA	NA	NA	NA
WP_086028371.1\|120326_121123_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_103412161.1\|122122_123361_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	1.2e-90	46.5
WP_086028371.1\|124260_125057_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_086028371.1\|125162_125959_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	5.4e-31	36.9
WP_103412184.1\|126374_127355_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	6.0e-40	33.5
WP_103412162.1\|129014_129755_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.6e-45	42.3
WP_158652726.1\|131969_132161_+	hypothetical protein	NA	NA	NA	NA
WP_103412164.1\|133444_133693_-	hypothetical protein	NA	NA	NA	NA
WP_103412165.1\|134310_134922_+	recombinase family protein	NA	NA	NA	NA
WP_103412166.1\|135021_135576_+	hypothetical protein	NA	NA	NA	NA
WP_103412169.1\|136321_136642_-	hypothetical protein	NA	NA	NA	NA
WP_103412170.1\|136658_137423_-	ParA family protein	Q8JL10	Natrialba_phage	1.6e-16	34.2
WP_103412171.1\|137735_138668_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	9.0e-70	50.8
WP_103410501.1\|140389_141628_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	4.7e-90	46.2
WP_103412172.1\|142223_145229_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	68.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP026318

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP026318_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP026318_1

26901-27189

Orphan

Consensus_repeat	Method
TAACTATTACCTTTTACTCCGGCTT	CRISPRCasFinder

5 spacers

The CRISPR arrays of NZ_CP026318_1

>merge|NZ_CP026318|1|26901-27189|CRISPRCasFinder
AAACTATTACCTTTTGCTCCGGTAACTAGATCACTTTACTCCGGTAACTATTACCTTTTACTCCGCTAGATAGATCGTTTTACTCCGGTAACTATTACCTTTTACTCCGGCTTGAGGTGTAAGTTTGTTGATAAATGGCTATTTATGTCCTTGATTCGTTGATTTTTTCTATAACTATTACCTTTTACTCCGCTTTGGCGCTCAAAACTCTCTATAAAACCTTTACTATTACTTCTTACTCCGGTATTAAAGGCAATAAATCACAATAAATGACTTCTTACTCCGGCAT

>NZ_CP026318|1|1|26901-27189|CRISPRCasFinder
AAACTATTACCTTTTGCTCCGGTAA	CTAGATCACTTTACTCCGG
TAACTATTACCTTTTACTCCGCTAG	ATAGATCGTTTTACTCCGG
TAACTATTACCTTTTACTCCGGCTT	GAGGTGTAAGTTTGTTGATAAATGGCTATTTATGTCCTTGATTCGTTGATTTTTTCTA
TAACTATTACCTTTTACTCCGCTTT	GGCGCTCAAAACTCTCTATAAAACCT
TTACTATTACTTCTTACTCCGGTAT	TAAAGGCAATAAATCAC
AATAAATGACTTCTTACTCCGGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP026318.1\|WP_103412212.1\|11656_13423_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412222.1\|29360_29621_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412226.1\|31031_31448_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412275.1\|13464_13704_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412216.1\|22824_24489_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222857
NZ_CP026318.1\|WP_103412228.1\|32377_33166_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|115680
NZ_CP026318.1\|WP_103412211.1\|11370_11682_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412227.1\|31475_32387_+\|recombination-associated-protein-RdgC	unknown	unknown	gnl\|CDD\|234726
NZ_CP026318.1\|WP_103412225.1\|30561_30843_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235239
NZ_CP026318.1\|WP_158652730.1\|15242_22175_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|376242
NZ_CP026318.1\|WP_103412220.1\|27275_28322_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP026318.1\|WP_103412224.1\|29990_30356_-\|DUF4406-domain-containing-protein	unknown	unknown	gnl\|CDD\|379581
NZ_CP026318.1\|WP_103412215.1\|22262_22679_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412217.1\|24481_25513_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184696
NZ_CP026318.1\|WP_103412221.1\|28516_29359_-\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	unknown	unknown	gnl\|CDD\|273146
NZ_CP026318.1\|WP_103412223.1\|29638_30001_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412213.1\|14180_14933_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312075
NZ_CP026318.1\|WP_103412230.1\|34260_34800_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_103412218.1\|25632_25968_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP026318.1\|WP_158652731.1\|25960_26620_-\|cobyrinic-acid-ac-diamide-synthase	unknown	unknown	gnl\|CDD\|222854

Protein	Function_ID	Function_description	E-value
NZ_CP026318.1\|WP_158652730.1\|15242_22175_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|376242	pfam18823, InPase, Inorganic Pyrophosphatase. A type I Inorganic Pyrophosphatase family domain that is found in polyvalent proteins.	1.51823e-42
NZ_CP026318.1\|WP_103412220.1\|27275_28322_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	3.01786e-23
NZ_CP026318.1\|WP_103412224.1\|29990_30356_-\|DUF4406-domain-containing-protein	gnl\|CDD\|379581	pfam14359, DUF4406, Domain of unknown function (DUF4406). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 98 and 145 amino acids in length.	6.53667e-23
NZ_CP026318.1\|WP_103412225.1\|30561_30843_+\|hypothetical-protein	gnl\|CDD\|235239	PRK04172, pheS, phenylalanine--tRNA ligase subunit alpha.	0.000182236
NZ_CP026318.1\|WP_103412217.1\|24481_25513_+\|hypothetical-protein	gnl\|CDD\|184696	PRK14474, PRK14474, F0F1 ATP synthase subunit B; Provisional.	0.00362565
NZ_CP026318.1\|WP_103412213.1\|14180_14933_-\|hypothetical-protein	gnl\|CDD\|312075	pfam08448, PAS_4, PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.	2.0286e-05
NZ_CP026318.1\|WP_103412216.1\|22824_24489_+\|hypothetical-protein	gnl\|CDD\|222857	PHA02531, 20, portal vertex protein; Provisional.	8.45602e-07
NZ_CP026318.1\|WP_103412228.1\|32377_33166_+\|hypothetical-protein	gnl\|CDD\|115680	pfam07042, TrfA, TrfA protein. This family consists of several bacterial TrfA proteins. The trfA operon of broad-host-range IncP plasmids is essential to activate the origin of vegetative replication in diverse species. The trfA operon encodes two ORFs. The first ORF is highly conserved and encodes a putative single-stranded DNA binding protein (Ssb). The second, trfA, contains two translational starts as in the IncP alpha plasmids, generating related polypeptides of 406 (TrfA1) and 282 (TrfA2) amino acids. TrfA2 is very similar to the IncP alpha product, whereas the N-terminal region of TrfA1 shows very little similarity to the equivalent region of IncP alpha TrfA1. This region has been implicated in the ability of IncP alpha plasmids to replicate efficiently in Pseudomonas aeruginosa.	3.22344e-17
NZ_CP026318.1\|WP_103412221.1\|28516_29359_-\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	gnl\|CDD\|273146	TIGR00571, DNA_adenine_methylase, DNA adenine methylase (dam). All proteins in this family for which functions are known are DNA-adenine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). The DNA adenine methylase (dam) of E. coli and related species is instrumental in distinguishing the newly synthesized strand during DNA replication for methylation-directed mismatch repair. This family includes several phage methylases and a number of different restriction enzyme chromosomal site-specific modification systems. [DNA metabolism, DNA replication, recombination, and repair].	4.92876e-42
NZ_CP026318.1\|WP_103412227.1\|31475_32387_+\|recombination-associated-protein-RdgC	gnl\|CDD\|234726	PRK00321, rdgC, recombination associated protein; Reviewed.	1.56729e-157
NZ_CP026318.1\|WP_158652731.1\|25960_26620_-\|cobyrinic-acid-ac-diamide-synthase	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	5.65296e-33

>NZ_CP026318.1|WP_158652731.1|25960_26620_-|cobyrinic-acid-ac-diamide-synthase
MIILVFGQRGGAMKSICSQNLAVELAHRHNSVCLVDADPGGTTANFGAYREEEGIEPPIFCVQKRGKITKTLQELDTKYDYVIVDVQGNIDPTRTQEMRSGLLAADIALAPFRPTQDHRDSILEVQDLIDTAKDFNSKLKTFCMISIAPTHTAREQDIIFTKSTLKEYSSMEVLETVAYNRVVYSDAYAIGRGVREMSDAKAKAEMNNLVNELLEKANG
>NZ_CP026318.1|WP_103412218.1|25632_25968_-|hypothetical-protein
MADNTKRFRQPIRKNQTPEKNADAFINGDVDSQQDEVSQEWYKALESTDKTKSSEKPVHINLNEYYREWGTKLAELDPQFANRKHLCQVLIAEGMNKLIEKTLKEQKKKEA
>NZ_CP026318.1|WP_103412217.1|24481_25513_+|hypothetical-protein
MSKKILQSITCTFNIFDTGRKYTGKQRGYILDNVKSVLTAPEVEERLRLRELVGYVSHGLREMAGKLTLGETLPVHLPNGQMTVVNAIPACVTVGLSIDDDGNLTHTQEVLDNDEGRKLLGLHNSRIGGFSWACGGGKVGGNTLINGFYGFDYVHNPLFAGNRGYVLDSASAEDEFDRQAVLDNLTSAGVPEDEREMVLDSFNASMAFESAHFKGMLLDAQQVIADQDEKAQELQQLLDSATEETETLKSEKTNREQFFKQLQERSHVAITDQVLDALINADSEESMETIMQMIMDTANISTQHLPIAGHKKTFVKQSTETDERGDKNDPFSINASMDAGFYD
>NZ_CP026318.1|WP_103412216.1|22824_24489_+|hypothetical-protein
MAEKKKRWWQQLSQMFQGQQDDDHSGHLELAESGFDYEDAGKLDDLLGKEGANSESETEKLIEPFPRNRRAGYLRYEEMAVDPTIDSALKMHVANALSAKTDTQEILFIASTKEGEGDKIVKDLRNTIGRWLNENAEAIAFQAAKYGLSYVRPYIEPQKGITHIRFDHYTHPAHIRCYERAGLLCGYTSKYQRSLEKKGLVELMEPWKFIQFKIPKWDGHGSTLIEPVRLNPLAFDINDDDYLNEEPVETQDYGSSLLRSAYDPWVDLNEAILSLNSARKNAAKRDRFITIQTGKKNPTLAAQYYNTILGALKRKLNLSAKRSAKRGHISTIDNHILPVTADGSGQVNIQTEQSDVNISHIEDVNFHVNRLCSALGVDKSLVGFTEDMSGGLGEGGWWTQSMVAAIKANLIRRAIKAGAEKLCEIHVLMKWGKVYTETDKPWRIEFNSLNNVLEREEATARESRINFATSVVTLMQMLDPELNKFNFKQTSNWLFTDVLRVSEETFKQLIEAAKDGDQDEVDKVLDSVSDPDSHNQLKTMIYSCIAELMGEENV
>NZ_CP026318.1|WP_103412215.1|22262_22679_+|hypothetical-protein
MKIKIPTQAELQPLYDEATEGQTEEQWMETFLSAVAKMLRKNPLWYRAYGIYWWGIKQMLIERELVSSDFIDAEWLEKIHYEKPAYLLLAGFAYHDERQDIGALEDDTHVIEFEDGAIDSYILIDEDFELVAVANAIA
>NZ_CP026318.1|WP_158652730.1|15242_22175_+|DEAD/DEAH-box-helicase-family-protein
MIKNFIRFHGMTPDGRIAQLPEMAPMSAHYSFTTKAAIEQGFSIAFIEGEQKPYPHRDVVFDSAEDEEPSFTTKPQSFKLQDRYQFQGLPISIENKAGTKRSGVDPDGSEWAVSMHYDYGYIRSTKGTDQEGIDCYVGPNRKADHVYIVKQHAIEKIKQWSSKYCPQCKEHVQDCACPEFFDEDKVMLGFDNKEQARAAYLKQYDSDLFLGPISTMRIEDFKKAIAEADGEELDLPLQFVHDHAVLDSATDEQVQALLAAKDINELEATFNQIFQPVAFAGDREFGLKASGVKTREAINNKVKAIVDRIKASNWDTSTLTAEDYDLLVQYSGRGGLSENSQYEYYTPTYIAEGCWELLSANGFDNGNVLEPSAGAGVFNATKHQGVKMTATEIDPISSAVNKILHPEDNVFNQSFEKMAVESPDNHFDSVIGNIPFGSARGASAHDDPDHKSEKLIERYFINRLIDKVKPSGLLVLVVPVNIVRERGKAWQKWRAKISKKAEFLGAHKLPSKTFGKQGTGVVTDIIVLRKHSKNAAEKIAQLPMEQLQAANVLWDTFLEGKWWERDGKPFIHGKFVPKDASKVRDDDKVIRDASVTDVALKRKLAAKFHSRIDWEALDTAEPAIKNYVEGDRRVIDERTYEFTRGNWEPVDALQTTTDIDESKYGVASLEALHGLLESNHGLMSLSVKQAFAAMKAWGHLFSKPQKQAIEFAMTQPSDEYREQIFRGSLIGADLARFQNDTNQGNWNATEQMRLQELVANEINKYGHPKQNRGLILAGERSRYFGVFSNAMDENGDYSTLLTGEVSTKGLAFDDTNPHAIVEHLYLREGMMHITLEDIQQLYKGKTPIQSLSDLADDKNLAIHPDGLVMPMSRFCSGDVYQKVLTLSHALNVETDPKLKAKYQQQLEEIEQRRYKTQPENIAFSMRHKWIDRQYVLEFMHEKGYSNLDYLVDKKQVATDDDTGGSFVENVKVRDTSSPFGEFVGYEDNQGFNKQLNSWLNGGNVTSSKQEYIEEYKERVARLDEEFRLWMQQHKDIDDLAELYNQKFNSYIPFEHSDADLGLEGVSAMVKPHGYQCSAVRRLSEDGSGILGFDVGLGKTFSALALAAYNKQMGRANKTLIVVPNSVLANWYHEAKMFHGNLDNALFVGFKPKLDKDGQIQREAVKDEKGNPKKNKHTGDVEYQDILIKESAEEVFDKMHQIPQTSKSLVVMTFEKYKEIQMRPVNKHKYADKWVEKSLISDQMAASTVAGDDFSLGKGKDKISYKEAVRREALQQRFLEDGGHKKGEYPYFEDMGFQSVIIDEAHAFKNSFKAGDKTANIAYLPNPTESQRAIDMAMKMAYLRDQNEGRGPVLLSATPVTNSPLEIFNMLSLVLPVEEFEKFGVYTADDFVRVFGKVETVEKMTVKGEIVQKDGLVGFQNLDGLRNLFHRYTLMRNAEDVSLALPDAPETHESVDMTADQESAYESLREEAKEASKPARQRSANARALFAVMRDMDKVTTDMDLFNQTMTFTFPASKAKAVDQLIAALPASIEAERIEQTEDGEEVKRKVSIELDYQRKDESDSIVLVVPDVYEQAVLDRLNDAAIKPADVSHPLTPKYAKLVANLKAELEVKGKQIIFTEEKTQHHKLKRIIVNQLGLDEKQIGIINGSDAAGAKLQRIADAYNAGDIKIVICNKKAEVGVNLQKGTSAIHHLTLPWTPASIQQRNGRGVRQGNTASKVSLYYYLGKGSFDGYRLDLLNKKKSWMRDLFNGTESEAVNGNAIDNDDYLDMFEADPEAAKAKRMERLAQKQAERKRKSDLKCAVDLSQVIGLRSQLASWEADKAEDYNRLVERKDKAQASLSRIKEKGEDSSKAEQALARINKSLQDHDAKWEEDKAKLESRLSQRMTFLKQKASAGELPFDSTIIENPENAIVARDGSVLTVGTYFETDFGAILRIEQVEQSSRSVHYSVPVGDVSYYWWGRRNGEFMKADLDSMPDGLKHVSLSDDEVRVKQILSITYTYNTLSKLKKDQFVKYRDDIKLQGYGNFLFRVNGELTLASADQHPTEMLVYPDVSDNALKREIALHYLKLRREDKPMYAWREVVKPFFGDFYDQEIAEYGQKASQADVLAACDKAWMDYQPTLLEGIQLSSSLKGLPAAVAKHQAYRLARQDFQESAEDKAAELGDNRMEINRWVREFISGLESKLLDEAETAKRQAADAELEELKKNPAFKELPAEVKKGFEDIGVTARYNYKDVSIPRNGRYRARSLSAFQYFFLKDENGKAGKLFAAKDILKNRFGAKFCTAEGDWDGSWWYFPVSVDVKEVFEIIT
>NZ_CP026318.1|WP_103412213.1|14180_14933_-|hypothetical-protein
MTANKYKDCLKKNKHLCQRCYPRKDTSIHYGIHAGQFVLCDCLIAELMRYPGPAGIKGLNSEFLIMNCHYRELVDLPCGYSFYGKRLEEMPSCVRHETAKSYDMQDRLIMEERQAMIFADCDYFFGDSIKLHTVETQKYPLIDLSGNLIGIAFLINDFFRPMDSRHVKLPDFADLSTPLSMAESRLVFCKKMGLSDKESAERLGITPSTVRSLKARIRDKTGYSVSELRTLLSSHSSFRLITKSDSFRIR
>NZ_CP026318.1|WP_103412275.1|13464_13704_-|hypothetical-protein
MYERAVHQGYSTPPVELFQPYVLDFFTQADLPVLHSEAKVLPTAKELAEESLEKAKLELSLARIRLSVVEGMTRILGCE
>NZ_CP026318.1|WP_103412212.1|11656_13423_+|hypothetical-protein
MSKKDSQPKKKAVISAIQASSEIDGLSAVFLAAFGEMISAQTHQAKALKQKLIDTEDDLEKFQVWRDIVSLQVELSRYNDNRLELISEQGADLNSLRQAYIVPDDLDERQRQFWQQHGEQFLSKVIEPKKAQLLKDVAHNINELLRSNPDINKKIERLENEYISPLAEKARGVIGQIHEQGQSEALMSEFEMIRSAIESAHRTQIDPVLMASSEELDQTARLQLQALQDQKKRIGTELMSSVYDSLLAHSSVSQEEADLWATHQEISASAIARMRKSGYPESEVRRDMATYYRLLNGRLDNVRLVTTGSKRASAIINTATIDIDHDFDRRTLFHEMSHLLEADESVKLANQRFIQKRASGSPQRLSELTNNRSYKSDEIAIPDNFYSPYVGKVYESGATEVASMGIQQFSSLESMYALYDSDEEMFTLMVGMMTGVNDTLIQRQKKQLEKQVHGTSFANAVKKVIATLSWQDGHRMASDEAWQQALTGKGKTNAHNKKWGWTRTLGTCQLFPAKAPRQRKQIYGVTVMSGKQDQTRHFFRERVQAEIFMYLHELSARGIKPLPQSAFYLACNNQAPDWYQSDTELPLI
>NZ_CP026318.1|WP_103412211.1|11370_11682_+|hypothetical-protein
MLSGVEKLKLAKEIRQLRVQIKSASIKGIEKLKIAKQIKAIRAQIVGGAKKLASRLDELISGKFDHLEPVKFIAIVREISEESGEFESVKQPVVNYVEKRLPA
>NZ_CP026318.1|WP_103412220.1|27275_28322_+|replication-initiation-protein
MNDNDAPEQKLPKERTITSAVSADIHSDFFKKSHALVFSRLSLSPVEHDIFALLLSRLHKDQWEDFMAGKTPISPSYEFKSKVLCDWFCVEKEDLYNILYKPSERLAGKKIGVIQEGDSFDFIPLFKRVKYKHGTLTIKPNDELITEYLGISQGHAQIPHKSFRQIKTEHGKRLYTMLCRFKSPNTELHPQTIEDLHGFFGLLDRQGTLLKKTYAVNANFIKRIIKPAIQEIDEKESHIRFLIDDKTGNYGFSYIKEGRKVVGIKFLFQWQLPEKEVGVKVEKNLTYEDALKTFADVVDKRCIPSIEEINNLKEHLVRIGTEGHDFGSGFFSKLRESEEAAQEIEEKA
>NZ_CP026318.1|WP_103412221.1|28516_29359_-|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase
MKPLIKWAGGKTWLAKRAERIVNDIAPERVVEPFAGSAAFSLFYEFNNVTLNDANPALINLYKQLSNGYEIDPNDFLLEEEFFYSAREELNNSLLSGQELGEREAALFWYLCKHSFNGLVRQSKREGKFNMPFGDYKGIATPPDTKEFMRVAKNWTFSCGCFSSVDISDAQMVLMDPPYEKTFNGYTKDKNENLQDRIVSMLSGYDGAVIATNTLLPELTHIYREEGFTVYKTPVRRSISCKGSGRGKTFEMIALRGFSKKQFRRYMDGLQPYYPKPVNV
>NZ_CP026318.1|WP_103412222.1|29360_29621_-|hypothetical-protein
MSNHQQRYTRWQRIKTLGFHDLLIRFSSPYKLHFLAGLHAISINHGANITKEVTSLKSAFSDLDTEKAATAIIFHPQFGKTSNKKG
>NZ_CP026318.1|WP_103412223.1|29638_30001_-|hypothetical-protein
MKSKRSLVDAAIELANNQVEHTPEVCSHSSGKGETKGLFSAKWECLHCDGLGYTGDPVAIAKWFKSALIQRTEKIQQLGSHCGRLNDENDVLKVIYPDWEQKLKEHYEQETHDKCRSRFD
>NZ_CP026318.1|WP_103412224.1|29990_30356_-|DUF4406-domain-containing-protein
MSPEMAHVTCRAELTLESLKQLRKDAGKLTIYISGPMTGHRHFNHPEFFRIEEMIQDAGHIPLNPARNPKGLTYDQYMKLSFSDLFVSNAVVRLKGWMESKGALAEVFAAHSLGLMLIDEE
>NZ_CP026318.1|WP_103412225.1|30561_30843_+|hypothetical-protein
MLKNAEVRVLVILKKEKKNTIAMTDLTRRLNVNAGIKAAEKNQILESLKEQGLVAVERKQIPAMRRTPTLITLTEKGKQVLKGVESGDIEFET
>NZ_CP026318.1|WP_103412226.1|31031_31448_+|hypothetical-protein
MDKTETNQEREISLRKEEKIACAILKGAKTADVAAVNGMKYAACREILHKYCRRVNPQAYESINIDAANKDCHSPFLEQLRENKHQFISQTAPRDPEQLRREIEQQSERLTSAQITLRSERTILSQLEAELAAATQKK
>NZ_CP026318.1|WP_103412227.1|31475_32387_+|recombination-associated-protein-RdgC
MKPKNIMAYRFSRTVQLTPDQLSEQLSEFAFVPCGEQDKRKFGWAPVMGKHSDQLLHVGADWILLAARLQEKMLPASVIKEEVNERIDALEAAEGRPLKKKEKDNIKDDVVIDLLPRAFKRTNTTYVWICPKKELLFVDASSFKKAEDVLALLRKTIGSLPVVPVTFASAIEVTLTDWLKTGEVPSGFSLLEEAELKSVLEDGGQIRCKQQELTSEEIQSHIEADKVVTKLAVNWQDRVDFILSDDGSLKRLKFSDELTDQNDDIAREDVAQRFDADMVLFAGEFDAFLPQLFDALGGVATCQ
>NZ_CP026318.1|WP_103412228.1|32377_33166_+|hypothetical-protein
MSVKLIEKPWAKAVRCLPNELARYALFTVGTSQERRYYTKPILLGLLDGSHTPMELQFVGPELRQDDLDVYLELLHYARNADLSGKLKFKRAELMKSLGWARTPFYYERLLQCMRRLSQSNIEGLITRREEGDLIQHRFNFNLVDSFEYKDVNGAMARFWHYRLPVELVKFFTSSGFARIDLKRRQVLKNNNIAKWLQFYFASHKANNKYAVSVEKVMHSCGSKASDLKTFRQKLKTALKLLKAAGIVDAYIDKESDRILRK
>NZ_CP026318.1|WP_103412230.1|34260_34800_+|hypothetical-protein
MSKPFQVYWSEDSHITNKANWLHCVETDDPVRAEQMYFKLCKKMLGKQGYVFLQSSDPDVVPYGRFNTSVGISWNVDREEQEIRRWVAWAMPQEIPYKRWKAPTTYMVKGLKAAILLRSGEKIGCEISGEMIGRVLGRSSRGVRYWIAEDGESRSIDYANWRCLLEMAGFKNKPIETYL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP026318_1	1.1\|26926\|19\|NZ_CP026318\|CRISPRCasFinder	26926-26944	19	NZ_CP026318	Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence	26926-26944	1.0
NZ_CP026318_1	1.1\|26926\|19\|NZ_CP026318\|CRISPRCasFinder	26926-26944	19	NC_010113	Vibrio sp. 0908 plasmid p0908, complete sequence	12939-12957	1.0
NZ_CP026318_1	1.1\|26926\|19\|NZ_CP026318\|CRISPRCasFinder	26926-26944	19	NC_010113	Vibrio sp. 0908 plasmid p0908, complete sequence	12983-13001	1.0
NZ_CP026318_1	1.2\|26970\|19\|NZ_CP026318\|CRISPRCasFinder	26970-26988	19	NZ_CP026318	Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence	26970-26988	1.0
NZ_CP026318_1	1.3\|27014\|58\|NZ_CP026318\|CRISPRCasFinder	27014-27071	58	NZ_CP026318	Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence	27014-27071	1.0
NZ_CP026318_1	1.4\|27097\|26\|NZ_CP026318\|CRISPRCasFinder	27097-27122	26	NZ_CP026318	Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence	27097-27122	1.0

1. spacer 1.1|26926|19|NZ_CP026318|CRISPRCasFinder matches to NZ_CP026318 (Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence) position: , mismatch: 0, identity: 1.0

ctagatcactttactccgg	CRISPR spacer
ctagatcactttactccgg	Protospacer
*******************

2. spacer 1.1|26926|19|NZ_CP026318|CRISPRCasFinder matches to NC_010113 (Vibrio sp. 0908 plasmid p0908, complete sequence) position: , mismatch: 0, identity: 1.0

ctagatcactttactccgg	CRISPR spacer
ctagatcactttactccgg	Protospacer
*******************

3. spacer 1.1|26926|19|NZ_CP026318|CRISPRCasFinder matches to NC_010113 (Vibrio sp. 0908 plasmid p0908, complete sequence) position: , mismatch: 0, identity: 1.0

ctagatcactttactccgg	CRISPR spacer
ctagatcactttactccgg	Protospacer
*******************

4. spacer 1.2|26970|19|NZ_CP026318|CRISPRCasFinder matches to NZ_CP026318 (Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence) position: , mismatch: 0, identity: 1.0

atagatcgttttactccgg	CRISPR spacer
atagatcgttttactccgg	Protospacer
*******************

5. spacer 1.3|27014|58|NZ_CP026318|CRISPRCasFinder matches to NZ_CP026318 (Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence) position: , mismatch: 0, identity: 1.0

gaggtgtaagtttgttgataaatggctatttatgtccttgattcgttgattttttcta	CRISPR spacer
gaggtgtaagtttgttgataaatggctatttatgtccttgattcgttgattttttcta	Protospacer
**********************************************************

6. spacer 1.4|27097|26|NZ_CP026318|CRISPRCasFinder matches to NZ_CP026318 (Vibrio campbellii strain BoB-90 plasmid unnamed 2, complete sequence) position: , mismatch: 0, identity: 1.0

ggcgctcaaaactctctataaaacct	CRISPR spacer
ggcgctcaaaactctctataaaacct	Protospacer
**************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 2007

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103412200.1\|351_708_+	hypothetical protein	NA	NA	NA	NA
WP_103412201.1\|697_1207_+	hypothetical protein	A0A222YY05	Escherichia_phage	7.7e-15	32.0
WP_103412202.1\|1209_2007_+	hypothetical protein	Q71TC9	Escherichia_phage	1.1e-23	32.2

DBSCAN-SWA_2

5201 : 50035

Vibrio_phage(40.91%)

integrase

attL 11598:11613|attR 57142:57157

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_103412205.1\|5201_6626_+	lipopolysaccharide biosynthesis protein BplA	A0A222YWB2	Escherichia_phage	2.1e-57	33.6
WP_103412206.1\|6737_8141_+	hypothetical protein	NA	NA	NA	NA
WP_103412207.1\|8145_8583_+	hypothetical protein	NA	NA	NA	NA
WP_103412208.1\|8586_9141_+	hypothetical protein	NA	NA	NA	NA
WP_103412209.1\|9254_9857_+	hypothetical protein	O21969	Escherichia_phage	1.5e-09	34.5
WP_103412210.1\|9853_11365_+	hypothetical protein	Q1MVM7	Enterobacteria_phage	7.9e-15	28.0
WP_103412211.1\|11370_11682_+	hypothetical protein	NA	NA	NA	NA
11598:11613	attL	NA	NA	NA	NA
WP_103412212.1\|11656_13423_+	hypothetical protein	A0A077SK08	Escherichia_phage	3.0e-05	23.8
WP_103412275.1\|13464_13704_-	hypothetical protein	NA	NA	NA	NA
WP_103412213.1\|14180_14933_-	hypothetical protein	NA	NA	NA	NA
WP_158652730.1\|15242_22175_+	DEAD/DEAH box helicase family protein	Q1MVN7	Enterobacteria_phage	4.1e-284	35.2
WP_103412215.1\|22262_22679_+	hypothetical protein	NA	NA	NA	NA
WP_103412216.1\|22824_24489_+	hypothetical protein	A0A222YXQ7	Escherichia_phage	3.0e-76	33.9
WP_103412217.1\|24481_25513_+	hypothetical protein	A0A1B0V7I1	Salmonella_phage	3.6e-27	31.6
WP_103412218.1\|25632_25968_-	hypothetical protein	NA	NA	NA	NA
WP_158652731.1\|25960_26620_-	cobyrinic acid ac-diamide synthase	Q2A085	Sodalis_phage	5.8e-23	35.1
WP_103412220.1\|27275_28322_+	replication initiation protein	NA	NA	NA	NA
WP_103412221.1\|28516_29359_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	Q1MVI4	Enterobacteria_phage	3.0e-24	30.1
WP_103412222.1\|29360_29621_-	hypothetical protein	NA	NA	NA	NA
WP_103412223.1\|29638_30001_-	hypothetical protein	NA	NA	NA	NA
WP_103412224.1\|29990_30356_-	DUF4406 domain-containing protein	A0A0K1LK36	Vibrio_phage	1.2e-14	45.6
WP_103412225.1\|30561_30843_+	hypothetical protein	NA	NA	NA	NA
WP_103412226.1\|31031_31448_+	hypothetical protein	NA	NA	NA	NA
WP_103412227.1\|31475_32387_+	recombination-associated protein RdgC	A0A2I7RNT5	Vibrio_phage	1.4e-99	58.7
WP_103412228.1\|32377_33166_+	hypothetical protein	NA	NA	NA	NA
WP_103412230.1\|34260_34800_+	hypothetical protein	NA	NA	NA	NA
WP_103412276.1\|34989_35343_+	hypothetical protein	R9TNL4	Vibrio_phage	1.4e-15	40.4
WP_103412231.1\|35390_35636_-	hypothetical protein	NA	NA	NA	NA
WP_103412232.1\|35693_36017_-	hypothetical protein	Q6V7U0	Burkholderia_virus	1.1e-06	30.5
WP_103412233.1\|36076_36895_-	3'-5' exoribonuclease	A0A1I9KF44	Aeromonas_phage	4.7e-30	41.0
WP_103412234.1\|36905_37502_-	hypothetical protein	NA	NA	NA	NA
WP_103412235.1\|37550_38741_-	hypothetical protein	NA	NA	NA	NA
WP_103412236.1\|38792_38990_-	hypothetical protein	NA	NA	NA	NA
WP_103412237.1\|39066_39291_-	hypothetical protein	NA	NA	NA	NA
WP_103412238.1\|39462_40638_+\|integrase	site-specific integrase	A0A067ZJC5	Vibrio_phage	1.9e-69	38.7
WP_103412239.1\|40733_41246_+	PadR family transcriptional regulator	A0A2I7RSZ7	Vibrio_phage	5.9e-07	32.1
WP_103412240.1\|41295_42303_+	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	2.3e-127	67.2
WP_103412277.1\|42341_42668_+	hypothetical protein	A0A2I7QIG7	Vibrio_phage	4.0e-17	58.0
WP_103412242.1\|42928_43237_-	hypothetical protein	NA	NA	NA	NA
WP_103412243.1\|43550_43799_+	hypothetical protein	NA	NA	NA	NA
WP_103412244.1\|43866_44298_+	transglycosylase SLT domain-containing protein	K7RVN3	Vibrio_phage	1.4e-30	53.3
WP_103412245.1\|44294_44693_+	hypothetical protein	NA	NA	NA	NA
WP_103412246.1\|44679_44889_+	hypothetical protein	NA	NA	NA	NA
WP_103412247.1\|44875_45307_+	hypothetical protein	NA	NA	NA	NA
WP_103412278.1\|45766_46486_+	hypothetical protein	NA	NA	NA	NA
WP_103412248.1\|46475_48194_+	protein PacB	Q71T61	Escherichia_phage	1.9e-94	39.9
WP_103412249.1\|48824_49379_+	hypothetical protein	A0A2I7R6M5	Vibrio_phage	4.9e-23	36.9
WP_103412250.1\|49444_50035_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4J6I5	uncultured_Caudovirales_phage	5.6e-25	39.7
57142:57157	attR	NA	NA	NA	NA

DBSCAN-SWA_3

55414 : 74019

Escherichia_phage(54.55%)

integrase

attL 47958:47972|attR 72346:72360

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
47958:47972	attL	NA	NA	NA	NA
WP_103412256.1\|55414_56554_+\|integrase	tyrosine-type recombinase/integrase	A0A2I7QY74	Vibrio_phage	4.2e-37	33.9
WP_103412257.1\|56652_57066_+	hypothetical protein	A0A2I7RNG1	Vibrio_phage	3.6e-23	43.6
WP_103412258.1\|57393_57681_+	hypothetical protein	NA	NA	NA	NA
WP_103412260.1\|57983_58331_+	hypothetical protein	NA	NA	NA	NA
WP_103412261.1\|58346_59681_-	replicative DNA helicase	O80281	Escherichia_phage	1.3e-141	59.8
WP_103412262.1\|59695_60025_-	PemK family transcriptional regulator	Q708N9	Streptococcus_phage	6.9e-09	47.7
WP_103412263.1\|60024_60282_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_031847632.1\|60551_61178_+	hypothetical protein	NA	NA	NA	NA
WP_031847633.1\|61174_61489_+	hypothetical protein	NA	NA	NA	NA
WP_103412264.1\|61485_62664_+	hypothetical protein	A0A222YXT1	Escherichia_phage	8.8e-38	34.5
WP_031847635.1\|62663_63404_+	hypothetical protein	NA	NA	NA	NA
WP_103412265.1\|63400_64324_+	chemotaxis protein	NA	NA	NA	NA
WP_103412266.1\|64326_64524_+	hypothetical protein	NA	NA	NA	NA
WP_103412267.1\|64553_65234_+	hypothetical protein	NA	NA	NA	NA
WP_103412279.1\|65250_65436_+	hypothetical protein	M4QRN4	Micromonas_pusilla_virus	8.7e-09	46.7
WP_103412268.1\|65508_66240_+	hypothetical protein	NA	NA	NA	NA
WP_046376515.1\|66236_67235_+	hypothetical protein	A0A222YXZ0	Escherichia_phage	1.3e-26	27.1
WP_031847564.1\|68029_68239_+	hypothetical protein	NA	NA	NA	NA
WP_103412269.1\|68492_70094_+	hypothetical protein	A0A222YWC7	Escherichia_phage	3.6e-66	29.2
WP_103412270.1\|70157_70619_+	hypothetical protein	NA	NA	NA	NA
WP_103412271.1\|70625_72179_+	hypothetical protein	A0A1B0V7E4	Salmonella_phage	3.4e-61	33.0
WP_103412272.1\|72189_72861_+	hypothetical protein	NA	NA	NA	NA
72346:72360	attR	NA	NA	NA	NA
WP_103412273.1\|72860_73505_+	hypothetical protein	A0A222YY02	Escherichia_phage	5.5e-26	36.9
WP_103412274.1\|73518_74019_+	hypothetical protein	A0A222YWE4	Escherichia_phage	2.6e-15	32.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage