CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP025394	Kitasatospora sp. MMS16-BH015 chromosome, complete genome	16 crisprs	DEDDh,csa3,WYL,cas4,PD-DExK,casR,cas3,DinG,cas14j	0	4	4	0

1. NZ_CP025394

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP025394_1

• CRISPR_ID: NZ_CP025394_1
• CRISPR_location: 383511-383591
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_1

Consensus_repeat	Method
CCCCGGTTGGTCTCCTCCAACTCCTCG	CRISPRCasFinder

spacers of NZ_CP025394_1

>1.1|383538|27|NZ_CP025394|CRISPRCasFinder
GACAGCTCGGCGTAGAGCGCGACCACG

CRISPR arrays and Neighbor proteins around NZ_CP025394_1

CRISPR arrays

The CRISPR arrays of NZ_CP025394_1

>merge|NZ_CP025394|1|383511-383591|CRISPRCasFinder
CCCCGGTTGGTCTCCTCCAACTCCTCGGACAGCTCGGCGTAGAGCGCGACCACGCCCCGGTTGGTCTCCGCCAACTCCTCG

>NZ_CP025394|1|1|383511-383591|CRISPRCasFinder
CCCCGGTTGGTCTCCTCCAACTCCTCG	GACAGCTCGGCGTAGAGCGCGACCACG
CCCCGGTTGGTCTCCGCCAACTCCTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104814405.1|366228_367416_+|ionic-transporter-y4hA	unknown	unknown	gnl|CDD|223464
NZ_CP025394.1|WP_104814409.1|377178_378201_-|YdcF-family-protein	unknown	unknown	gnl|CDD|99750
NZ_CP025394.1|WP_174805614.1|367769_370274_+|DUF3516-domain-containing-protein	unknown	unknown	gnl|CDD|378795
NZ_CP025394.1|WP_104814414.1|386103_386946_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NZ_CP025394.1|WP_104814417.1|388272_389931_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP025394.1|WP_104814415.1|387146_387542_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NZ_CP025394.1|WP_158701968.1|378197_379244_-|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|224214
NZ_CP025394.1|WP_104814410.1|380660_382304_-|fused-response-regulator/phosphatase	unknown	unknown	gnl|CDD|369272
NZ_CP025394.1|WP_158701965.1|367515_367692_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104814411.1|384117_385329_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340411
NZ_CP025394.1|WP_104814407.1|370783_371287_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_158701966.1|370547_370757_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104814412.1|385316_385733_-|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|340411
NZ_CP025394.1|WP_158701971.1|391658_392393_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104814413.1|385729_386107_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NZ_CP025394.1|WP_104820572.1|389954_391064_+|cobalamin-B12-binding-domain-containing-protein	unknown	unknown	gnl|CDD|227345
NZ_CP025394.1|WP_158701967.1|371390_377150_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_158701970.1|387661_388051_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP025394.1|WP_158701969.1|380280_380631_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_CP025394.1|WP_104814418.1|391060_391414_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104814405.1|366228_367416_+|ionic-transporter-y4hA	gnl|CDD|223464	COG0387, ChaA, Ca2+/H+ antiporter [Inorganic ion transport and metabolism].	2.94684e-72
NZ_CP025394.1|WP_104814409.1|377178_378201_-|YdcF-family-protein	gnl|CDD|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	5.66411e-41
NZ_CP025394.1|WP_174805614.1|367769_370274_+|DUF3516-domain-containing-protein	gnl|CDD|378795	pfam12029, DUF3516, Domain of unknown function (DUF3516). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is typically between 460 to 473 amino acids in length. This domain is found associated with pfam00270, pfam00271.	0
NZ_CP025394.1|WP_104814417.1|388272_389931_+|serine/threonine-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	5.90607e-41
NZ_CP025394.1|WP_104814415.1|387146_387542_-|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	2.76785e-12
NZ_CP025394.1|WP_158701968.1|378197_379244_-|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	1.98771e-27
NZ_CP025394.1|WP_158701970.1|387661_388051_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	4.76714e-19
NZ_CP025394.1|WP_104814411.1|384117_385329_-|ATP-binding-protein	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	1.22638e-32
NZ_CP025394.1|WP_104814410.1|380660_382304_-|fused-response-regulator/phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	2.62909e-38
NZ_CP025394.1|WP_104814412.1|385316_385733_-|anti-sigma-regulatory-factor	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	1.66741e-36
NZ_CP025394.1|WP_104814413.1|385729_386107_-|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	7.5354e-30
NZ_CP025394.1|WP_104820572.1|389954_391064_+|cobalamin-B12-binding-domain-containing-protein	gnl|CDD|227345	COG5012, COG5012, Predicted cobalamin binding protein [General function prediction only].	9.9653e-13
NZ_CP025394.1|WP_104814414.1|386103_386946_-|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	4.10169e-42
NZ_CP025394.1|WP_158701969.1|380280_380631_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	7.18836e-18
NZ_CP025394.1|WP_104814418.1|391060_391414_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.12767e-16

Protein sequences

>NZ_CP025394.1|WP_104814410.1|380660_382304_-|fused-response-regulator/phosphatase
MTGAVPDAGPATVLVLDDNPTTRYIVGSWLRRAGHQVVEAVDGAEALALLAEAPAHRLPELALVDVRLPDMTGFEVCERIKKQPHTADLPVVHISATAIEASDRTQGLHRGADAYLTEPIDPAELQATVTAVLRYTRARRRAELLADRVAALHRSTLALYGATDAETMVTAAALGAIELGATTATAVLLGPHRETLHLAHCHPHPAAEPGPAVRLVTGSPALLDALAHHTLGDATGIDTVRLDAGQWQAALAENVPPGHGLPREDVTLVVARTKPGRPLVALVVDPPASAALDERRLLSQLTQATALALEALRSQAEEHALTLTLQRSFLPDRLPAPHGVDLAVRYEPASEQSEIGGDFYEAIETPAGLLLAIGDVAGHSLEAAMVMGELRHALRAYAIEGHHPHTLLERLDALLVQLRPGSTATVCLVLIEPGRRRIHLANAGHLPPLLRMPGGTTRFLTEHGILLGLNLPQPPATTYDTPPGSTLLLVTDGLVEVPGENLETGLEALRSSFAQGPADLDEAGDLLLHAFSSGQADDVALLLARLH
>NZ_CP025394.1|WP_158701969.1|380280_380631_-|STAS-domain-containing-protein
MPDYTLTIDVRTHETGATVVVLSGELDHYTAPRLRRTLERTPAGLLLVLDLTELRFCDSIGIAELVFASRRTPVPGARLPVVGAPADLRHLLALTGVESLLSHHEDVDRAVDASAP
>NZ_CP025394.1|WP_158701968.1|378197_379244_-|YihY/virulence-factor-BrkB-family-protein
MPARAFGLIGRIDDYQRRHRPLGLAVAVAHKFLDDQGGYLAALITYYGFLSLFPMLLLLVTALGFALHGNPHLQEEVLHSALRQFPVVGDQVAHDIRTFQGSGLALAVGIAGTLYGALGVAQAVQNAFDTVWAVPRHRRRSAVAARLRGLPLLGLLGAAAGVSSLPAAVSARLHGEPGWVGWTVGAAAVPVSIAVNGALLLAALKLLTDRELRMRLLWPEALGAAVAWQLLLSVGTYYVGHALRGATAYGLFGVVLGLLAWIYLAALTLVACAESGAVRLRRLWPRSLRSLFAEDAPMTGADERAQASYVSAAACTRRAEVTVVFRSVSLDVDPAVPRPSSAPVGEAR
>NZ_CP025394.1|WP_104814409.1|377178_378201_-|YdcF-family-protein
MTFLHLRYLLAAAVVVLSVAFLRRFLGDRRRLGNGVLLGLGALCLAGGALLEFHRLFRPAAGVVAGAVLAGAVLTAVVAAGFLLVNGVRMVRREGHRNPANLLSLLAGAGILLLLVLLAVAARAGGGPMRACAGGVLLVAGYLSFLLVCFAGYALLYQRVAVRRPVDFVVVLGAGLIEGSTVPPVLASRLDRALSLHRHQRARGRDPLLLVSGGKGDDEQVSEAEAMARYLTARGVPAAKVVQEPHSTNTEENLRFSRDLMERLRPGGRCVIVTNDFHALRAAITARRVGVRGEAAAAPTAAYYWPSATLREYAAILVAYPVTNSVVCGVLAATGALAGW
>NZ_CP025394.1|WP_158701967.1|371390_377150_+|hypothetical-protein
MTITQVDWIGRAPMVSSLTPHRTVRAAAVTAVLALAATLLGVPPAAAAGPVMSLTKAVEGAPNPLVPGSTFSYKLTLSCSSLSVSCVNAVLEDVLPAEFDQTSLPPTTPNQLVAYDPATRKLRVEFRSPLASPPNPAGSVGLPAGTTADVSIGMRVPENGPLEDGDSVTNTAVAKADNATEVLGTVTQTVTVPKNLDAKATKSWQPGSDVAQSDGESTVTLGTANTSAAVAGVSLLRIEDDTAAVYENFDLVSLGPVGRMPKGADQVTVRVCTKPPASPHPCAEGDWVNAPATPGPDLTLPPGVTAGQVTGVRFEFSNSTGAALPYDAEGATVPVKLKLRRTERTSGAAINPATRKTVHNCAEPSVKDAASRFTIIGLQACADHDILPNIATVDLDKRFFPDNRGDFTQNGTAVRGENSGVTAQLNATNSSPFAVSELTITEPSDSASAAHEFDKVDAAKLKLDFPAGATTAVLTVTCRDGSTVAPVTLANPPASQTRPSTGCPAGSPPKRISVTYRGEQNGAGTIKPGATGKLSVNGTLNSKVTAQDTKDGVRDCADASAANPANGSGSAAITACADLKVQERNPDGNGFKSASWTEIPPGQNLDFSLGYTNTGNVTQPNVRVTDPADPLAPGNPFDQLEIVGVQTDGSPRSLHIGLELYDPTVKTWVAYVPPDSALLARAKGVRITEPDGIPPQGFMRATVTVRLRPGVTSGTLRNCAVVSVNGVENGNPSCSPALEVKPPKAAASLQKTLVPATVLRPVTGVSPQDVTVRLTAVNTGNLGLKRLVVTDLDPGFFDAVTVSALSGVTFPNGADRVQVDVCTTGCRSVPPVFVNGTPTGSTKPGFPAGVAPADIQGLRVTFTSAKGGYDILPATGAPNWGDCPNSSVCLTVRPRTGLRSAPGTPIPDTVPDTAQAAGESTLQNPGTTFPIPDATATLSVREGTNKIRVEKEPAQTVLSPGAVAPFNLHVKNTGTAPVPDLVVVDEVPAGLRFDDAFQGDQGRPYTIRYQLPTGATQPAQVTFEPDRDASGRITKLRWRFTGWTFYPGSEVTLGYQVKLNGGVAAGTTITNEFGAGSDTVSKLNCDPSSPRLGTRQDDPRYGTGTFCTSTAQITTRSGVSFDAAKWVTGDRGLGYLDATGKPVPAGDPRCPELTVAGTTYTRYPCVALTLAGQDFSYLIRVENSGTEPARSLQLLDVLPAPKDTGVLLGDEQRGTQWDTVPALSGPVGYDGPGSAALTYTTTGNPCGRKVETPKRKCATASWNGATDRATAFEADVTFPAGLAPGAAVTFTVPLQAPTDLTMAEYPSVAWNSFAHTETVSVNGSLTRLPVTEPPKAGIGLLFGNIRIVKTVLDPPPGVPVGPFKLAYSCLVTTGSGAVVEVRSGEAEFGRDRPFDLTGVPVGAVCRFWETESAGAQSSNQGPGRAIVLTVVPAPDRATHQTGDISNQYPRKDLVIAKRVTGEAGQAVGQGPFKITVDCSFNGTRLPDFPQQLVFTGDDSQALTDLPEGARCQVDETDNGGATQVHYQLVSSARIDATTGRGTLDSVASVGPVATVIVTNEFATGSLRIAKKLTGPGGALATGPFRFAVDCEFNGRTGVVTHTLDLTGPDHLTGQLDGLPVGALCTVTETEAGGADQPAPPVRSVLIKEGLTDLATAELTNGFHAARLTLAKQLTGPLAQAGYLREAVFQLHVICRRDGLGVLDRTVTLRPGQPVTLPELLLTGTRCWAAELPGGATTVTVSHPDEQHAAEVTADSTGLTITATNDYRPTTLALLKHLAGPGAAAVGDREFTVELSCTLTTAPGTQPLVLVDRRRYQLRAGAPRQVDDLPAPLPAGSRCWLTEPDPAGADATTIEHDSPANALTLALDPATLDLTNRYDRTNPPPLPETGTDPHPWLTTSLALLLLGAVARTAAAARRRR
>NZ_CP025394.1|WP_104814407.1|370783_371287_+|hypothetical-protein
MDVEDVLDTPAEAAPLWCPSGHGREAESVVLGVRSQDDGGLTYLAEPMPAAEALALVPAGIEPTRVLRFASHCESGCAHRAGPECTLITKLRTLPPKAADAPLPHCHLRHHCKWWNQAGADACGRCPAVATTILSTETTVSRAADPSVTPEQLRAWIEANPTGPPGC
>NZ_CP025394.1|WP_158701966.1|370547_370757_+|hypothetical-protein
MISARRLTATAVVAAGLVAAGAATASAATPKPARIVTAADFRAHLAKAVAVEAANEGNTFDAQTPGKPA
>NZ_CP025394.1|WP_174805614.1|367769_370274_+|DUF3516-domain-containing-protein
MPKPATPDSLFETFAEWAMERGISLYPAQEEALIELVSGNNVILATPTGSGKSLVAAGAHFAALAEGKRTFYTAPIKALVSEKFFDLVKIFGTEQVGMMTGDASVNPTAPIICCTAEVLANIALRDGDRADIGQVVMDEFHFYAEPDRGWAWQIPILELPQVQFLLMSATLGDVRRFEEDLTRRTGRPTTVVRSATRPVPLFYEYRRTTLHDTLEELLKTGQAPVYVVHFTQKEAVERAQSLMSINMCSKEEKEAIADLIGRFRFTTKFGRNLSRYVRHGIGVHHAGMLPKYRRLVERLAQAGLLKVICGTDTLGVGVNVPIRTVLFTALSKYDGIRVRTLRAREFHQIAGRAGRAGFDTVGQVVAQAPEHVIENEKAVAKAGDDPKKKRKVVRKKAPEGFVGWTEEGFEKLIAADPEPLVSRFKVSHAMLLSVIGRPGNAFEAMRKLLTDNHEDRNAQRRHIRSAIAIYRSLLAGGVVERLAEPDAEGRIVRLTVDLQENFALNQPLSTFALAAFELLDRESPSYAMDVVSVVEATLDDPRQILASQQNKARGEAIGEMKRDGIEYEERMERLQEITYPKPLEELLNHAYEVYRQAHPWIGDHALAPKSVVRDLYERAMTFSDYVGHYDLARTEGIVLRYLAGAFKALEQTVPDDMKTDDLKDVIAWLGELVRQVDSSLLDEWEQLANPTDDQAPEISLDERPAPVTANERAFRVLVRNEMFRRVELAALEHYGTLGELDGEYGWDADRWADAMDAYWDEHDDLGTGPDARGPKMLLIDTSDAEEEYSWRVRQIFDDPAGDHDWGISAEVDLVGSNEEGRAMLRVTAVDRLDG
>NZ_CP025394.1|WP_158701965.1|367515_367692_+|hypothetical-protein
MARPVRWLGVISATVLLLGAAVAAPATTADRPGPIGWFAYAPLPAPGAGVPGPAPQSR
>NZ_CP025394.1|WP_104814405.1|366228_367416_+|ionic-transporter-y4hA
MIAELRKWTTLVPVLAFVLLALTWGRSLPGGLVALVAVFLAGAVLAAVHHAEVIAHRVGEPFGSLVLAVAVTIIEVALIVTLMADGSEKNATLARDTVFAAVMITCNGIVGISILVTALKHRVAVFNSEGTGAAFGAIATLAVLSLVLPTFTTSTPGPQFSPTQLVFAATASLIVYLLFVATLTVRHRDYFLAPSRQPARATADATATAVPAVSPGSPTPTQTPTPAPAPAPAPADEEHAAPPTSREAWLSLSLLGVALVSVVGLAKGVSPTIERTVADAGLPASVVGVVIAMLVLLPETISAIRSAARDRMQTSLNLAHGSALASIGLTIPAVAVASTWLSGPLVLGLDPTHMVLLALSIAVGTLTVMPGRATPLQGGVHLAVMAAYLVLAVSP
>NZ_CP025394.1|WP_104814411.1|384117_385329_-|ATP-binding-protein
MGTLTVPLMECEDAAWFRDSESLAAAARSGARSLAQRAALLPERVAEVALAVSEAATNLRRHAKDGSLLLRVVRTDSEAALECVTLDHGPGMPDIARALTDGVSSGGTLGIGLGAISRLADTFDVHSLPGRGTVMTARFWNRTPGGRLAAAGGEAVVTGITRPMSGQELCGDAWAARTLPSSHPPAPVPSRPYRSPGTLDWSVLTGTAGRPGPTRSDRWAPVPAGASTAPPPEESGAFLVMFCDGLGHGPLAAKAALDAVAAFRHTTATTPDGVLADIHHALRSGRGGAVAVGLVEPAERRVGVCGVGNISTFTVDPATGARRSLPSAPGIVGHQLPALRTVRQQLAPGSAVVMHSDGLTDRWQAAALPGMCAQLPVTAAALLLREAGVRRDDAGVLVAKGLW
>NZ_CP025394.1|WP_104814412.1|385316_385733_-|anti-sigma-regulatory-factor
MTRSAEDVAQTVPIVSNDDVVRARQLVRTLAQQCGLSLVDQTKLVTAASELARNTLVYGGGGAMRCATVQRDGRRGVHAVFEDTGPGIPDLDLALTDGWTSGGGLGLGLSGARRLVDDFELESRTGIGTKVSVTKWAR
>NZ_CP025394.1|WP_104814413.1|385729_386107_-|STAS-domain-containing-protein
MTDRVPVLKLGNVLLVSIQIDLEDQTVLDLQDDLAERIVATGAIGVVIDITALEIVDSFVGRMLANTAAISRMLDAETVVVGMRPAVAITLVELGLSLGGVRTALTLEKGLALLERDRVAGADRG
>NZ_CP025394.1|WP_104814414.1|386103_386946_-|STAS-domain-containing-protein
MAAEESSDRLVELLTRDGEVLDRWVEAVAAILRGRISRAELERELTDLYQALVQALRDGGPDWRAEGYSEVRALLVELSRNRAQHGFTPTETATSVFACKDVLEPTTATSAEDIAAYLQLARLLDALGLFTIEAYARTREEIISAQAEQLLELSTPVVKLWEGVVAVPLVGTLDSARTQIVMEKLLQSLVDSESEHAIIDITGVPAVDTEVAQHLLKTVVAARLMGAECTISGIRPQIAQTLVALGVQFGDIVTKASLADALRYVLQRIGTAAALTGGLK
>NZ_CP025394.1|WP_104814415.1|387146_387542_-|ATP-binding-protein
MPEPSTRFDLPVTTAGQARSAITTLLDRVPGDTRAVRVDAHLVATELVTNALRHGGGVTGFRTWLTADATVLCIEVQDAADRRPQEPAPEDRGPDRLGGRGWTIVLSLAATCVVRPLPARGKCIAVTLPVR
>NZ_CP025394.1|WP_158701970.1|387661_388051_-|STAS-domain-containing-protein
MTETTDPNGHGARAADDHPSVLARGELDWENADEFARRIRAACGRSPRLLTVDLSAVTFADSSVLHTLFEAHRQLAATGGRLLIAGPLHPSVQRLFEVSATIGHFHFAPPVEQAADAPAGKTPSTSNGR
>NZ_CP025394.1|WP_104814417.1|388272_389931_+|serine/threonine-protein-phosphatase
MTFPQTETSIAPGETEPSFLAAAPYPVLVLATDGTVRDASDAAWELLGRPAGRDAAAVPWLLEAHLRLLATASGRADGAAPAATVHGRVAGGEVEAHPSVRPDGSVVWWLVDRADHRLTAEQDRWELLAELSGLLLSSLNVDRCLETTAQQAAAHLADAAVVVSPTGGRVLRFVSCVRGGRPQHGRARVDPADVPGLAEALRGFPPVPSRWIDPATAPDWLRPEGMTAVGAVSVTPLPGHGVPAGALVLLRGPGEGAFTQAEEVFARLFAARAGAAVSAAVMYSEQAAVTDLLMRDLLPPRLEHLDGADFAGGYRASEDRARIGGDFYDVHPAADPGGETLAVLGDVCGKGLEAAVLTGKIRNTLHALLPLADDHPRLLAMLNRALLTSHHTRFATMVLASVRRRSDRVTVRLSAAGHPAPLIVRADGRVEASPTCGSLVGVLPETTVESDTVELAPGEACVLYSDGVTEARGGPLGEAMFGEERLRRELGQCARMPAEAIVERVLMLASQWVGGGRHDDMAVLVVAAPQEGRLTPSDGHRAAVTGPQGCAA
>NZ_CP025394.1|WP_104820572.1|389954_391064_+|cobalamin-B12-binding-domain-containing-protein
MSVSAAGATDPTEWAEQLWEAVETGREAAAAAVVFGALTAGVDPEAVLLDVIATVQARIGHAWAADRMTVAQEHAATAVNDRVVAALAHHPAVLDATPRTTRGRVTVSCVDGEWHAFPARLLSQVLTLRGWEVDHLGAQVPTPHLITWLHRTGPAAVALSASLAPRLPAAHAAITAAQAAGFPVLAGGAAFGPGGRYARLLDADAWAGDARGAADRLAEGLSAPAPVHQPVDDLPHLADQEYTLVRQSAQRLVRAVVSGLTERSPVVRAYTELQVQHTAEDVAHLVDFLAAALYVDDPDLFGGFLAWTADVLDARAVPAASLVPTLDILRRELRDLPRAVAQLDHGRDVLERRPGPPPTVPHQHFRART
>NZ_CP025394.1|WP_104814418.1|391060_391414_+|STAS-domain-containing-protein
MTAPRDPSAIPAPDAPGPQSSTVTVRVEGDLDYETCDALLAAVAEAVAARPTATALRLDCAAMTLCDSMGLSALLQLRRQTEGTGQRLLIDRRPPHLDRLLQLTGTHDYLLGPSDPS
>NZ_CP025394.1|WP_158701971.1|391658_392393_-|hypothetical-protein
MTIQGERAPRPAGGPEAPVPATVHRSRRTPSRRILVGAVLAVLAAGAGWIVTRPHPGDWIPGLGPTSAESAKSAPTAAAVAAPTQTSVFTPESFTADRYFPAARAVDLDDFKGRRTAGRQGGDCAESLADRAHNLFVNTGCQGYVSVGFARTDQQLLGSVTVLRFGDAGAAAKMSQTLDAAAFAFTTEPELPVPAGRPSTRIEAVGQYVTVTTVRSTDTHAARPDLDAAARALSYTAGASFGWM

Crispr_ID: NZ_CP025394_2

• CRISPR_ID: NZ_CP025394_2
• CRISPR_location: 474315-474397
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_2

Consensus_repeat	Method
CCGGTCACCGGACGCTCCACTCGA	CRISPRCasFinder

spacers of NZ_CP025394_2

>2.1|474339|35|NZ_CP025394|CRISPRCasFinder
AGTGGCCGGCCAGGGACGGGACGAGGGACAGGTAC

CRISPR arrays and Neighbor proteins around NZ_CP025394_2

CRISPR arrays

The CRISPR arrays of NZ_CP025394_2

>merge|NZ_CP025394|2|474315-474397|CRISPRCasFinder
CCGGTCACCGGACGCTCCACTCGAAGTGGCCGGCCAGGGACGGGACGAGGGACAGGTACCCGGTCACCGGACGCTCCACTCGA

>NZ_CP025394|2|2|474315-474397|CRISPRCasFinder
CCGGTCACCGGACGCTCCACTCGA	AGTGGCCGGCCAGGGACGGGACGAGGGACAGGTAC
CCGGTCACCGGACGCTCCACTCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104814477.1|467778_468573_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP025394.1|WP_104814488.1|491253_492219_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_CP025394.1|WP_104814479.1|469332_470238_+|isopenicillin-N-synthase-family-oxygenase	unknown	unknown	gnl|CDD|226022
NZ_CP025394.1|WP_104814480.1|470508_470850_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104820583.1|463368_464379_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NZ_CP025394.1|WP_104814475.1|464403_466113_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173871
NZ_CP025394.1|WP_104820585.1|475541_480287_-|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|238429
NZ_CP025394.1|WP_104814489.1|492220_493528_-|protocatechuate-4,5-dioxygenase-subunit-alpha	unknown	unknown	gnl|CDD|106330
NZ_CP025394.1|WP_104814482.1|472013_473141_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|372616
NZ_CP025394.1|WP_104814486.1|487547_488561_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NZ_CP025394.1|WP_174805615.1|462382_463318_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223674
NZ_CP025394.1|WP_104814487.1|488771_489749_+|glycoside-hydrolase-family-6-protein	unknown	unknown	gnl|CDD|376532
NZ_CP025394.1|WP_104814485.1|480295_487237_-|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|274311
NZ_CP025394.1|WP_104820584.1|475218_475518_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|180033
NZ_CP025394.1|WP_174805617.1|490054_491116_+|glycoside-hydrolase-family-6-protein	unknown	unknown	gnl|CDD|376532
NZ_CP025394.1|WP_174805616.1|468589_469336_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224051
NZ_CP025394.1|WP_104814491.1|494478_495168_-|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	unknown	unknown	gnl|CDD|181735
NZ_CP025394.1|WP_104814476.1|466835_467714_+|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270248
NZ_CP025394.1|WP_104814490.1|493555_494476_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|238636
NZ_CP025394.1|WP_104814481.1|471008_471926_+|glutaminase	unknown	unknown	gnl|CDD|234880

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104814477.1|467778_468573_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.00773e-61
NZ_CP025394.1|WP_104814488.1|491253_492219_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.60145e-47
NZ_CP025394.1|WP_104814479.1|469332_470238_+|isopenicillin-N-synthase-family-oxygenase	gnl|CDD|226022	COG3491, PcbC, Isopenicillin N synthase and related dioxygenases [General function prediction only].	9.75874e-73
NZ_CP025394.1|WP_104814481.1|471008_471926_+|glutaminase	gnl|CDD|234880	PRK00971, PRK00971, glutaminase; Provisional.	3.26868e-162
NZ_CP025394.1|WP_104820583.1|463368_464379_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.11876e-75
NZ_CP025394.1|WP_104814475.1|464403_466113_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	6.01347e-165
NZ_CP025394.1|WP_104820585.1|475541_480287_-|type-I-polyketide-synthase	gnl|CDD|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	3.39467e-140
NZ_CP025394.1|WP_104814491.1|494478_495168_-|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase	gnl|CDD|181735	PRK09262, PRK09262, hypothetical protein; Provisional.	1.24315e-137
NZ_CP025394.1|WP_104814482.1|472013_473141_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.32635e-25
NZ_CP025394.1|WP_104814486.1|487547_488561_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.05503e-102
NZ_CP025394.1|WP_174805615.1|462382_463318_-|ABC-transporter-permease-subunit	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.4909e-93
NZ_CP025394.1|WP_104814487.1|488771_489749_+|glycoside-hydrolase-family-6-protein	gnl|CDD|376532	pfam01341, Glyco_hydro_6, Glycosyl hydrolases family 6.	1.97529e-64
NZ_CP025394.1|WP_104814485.1|480295_487237_-|type-I-polyketide-synthase	gnl|CDD|274311	TIGR02813, omega-3_polyunsaturated_fatty_acid_synthase_PfaA, polyketide-type polyunsaturated fatty acid synthase PfaA. Members of the seed for this alignment are involved in omega-3 polyunsaturated fatty acid biosynthesis, such as the protein PfaA from the eicosapentaenoic acid biosynthesis operon in Photobacterium profundum strain SS9. PfaA is encoded together with PfaB, PfaC, and PfaD, and the functions of the individual polypeptides have not yet been described. More distant homologs of PfaA, also included with the reach of this model, appear to be involved in polyketide-like biosynthetic mechanisms of polyunsaturated fatty acid biosynthesis, an alternative to the more familiar iterated mechanism of chain extension and desaturation, and in most cases are encoded near genes for homologs of PfaB, PfaC, and/or PfaD.	2.11574e-171
NZ_CP025394.1|WP_104820584.1|475218_475518_-|acyl-carrier-protein	gnl|CDD|180033	PRK05350, PRK05350, acyl carrier protein; Provisional.	4.75344e-08
NZ_CP025394.1|WP_174805617.1|490054_491116_+|glycoside-hydrolase-family-6-protein	gnl|CDD|376532	pfam01341, Glyco_hydro_6, Glycosyl hydrolases family 6.	9.04652e-37
NZ_CP025394.1|WP_174805616.1|468589_469336_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	9.57872e-135
NZ_CP025394.1|WP_104814476.1|466835_467714_+|amino-acid-ABC-transporter-substrate-binding-protein	gnl|CDD|270248	cd13530, PBP2_peptides_like, Peptide-binding protein and related homologs; type 2 periplasmic binding protein fold. This domain is found in solute binding proteins that serve as initial receptors in the ABC transport, signal transduction and channel gating. The PBP2 proteins share the same architecture as periplasmic binding proteins type 1, but have a different topology. They are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the family includes ionotropic glutamate receptors and unorthodox sensor proteins involved in signal transduction.	8.39888e-61
NZ_CP025394.1|WP_104814490.1|493555_494476_-|amidohydrolase-family-protein	gnl|CDD|238636	cd01311, PDC_hydrolase, 2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM). This reaction is part of the protocatechuate (PCA) 4,5-cleavage pathway. PCA is one of the most important intermediate metabolites in the bacterial pathways for various phenolic compounds, including lignin, which is the most abundant aromatic material in nature.	2.06966e-101
NZ_CP025394.1|WP_104814489.1|492220_493528_-|protocatechuate-4,5-dioxygenase-subunit-alpha	gnl|CDD|106330	PRK13372, pcmA, protocatechuate 4,5-dioxygenase subunit alpha/beta.	0

Protein sequences

>NZ_CP025394.1|WP_104814482.1|472013_473141_-|class-I-SAM-dependent-methyltransferase
MTTTEPPSAPASGPAPAPAAAGKAALRARQVAARRPAYRAELADGTERFFEARRADCPWCGSDRLRIRLRTTDLLQHKPGRFVLDECQDCAHVFQNPRLTGEGLEFYYRDFYDGLGEQRLGGVFGTRTAAYRGRARSVAPFAAAPVSWLDVGTGHGHFCETAREVFPDTAFDGLDLSEGAELAEHSGRLAHGFRGSLPELAPGLAGRYEVVSMFHYLEHSTDPVRELAAAHRVLRPGGLLLIEVPDPQSRYARLLGRWWLPWLQPQHLNLMPAANLRRRLGELGFSVVLEQHREPHDPVDLLAACWLLLDAAAPREDAPWLPGTPPGRLRRTLRGAVFLAGAPVLLLASLLDRLAARSAGRTGLSNAYRLLARRE
>NZ_CP025394.1|WP_104814481.1|471008_471926_+|glutaminase
MDDRDLFECITRAVQPVLAQGRVASYIPALAAVDPHRFGLAIADTDSRTVPRGTGDWQVPFSIQSLSKVFTLALVLAADGETLWSRVGKEPSGAAFNSLAQLEREQGIPRNPFVNAGALVVTDRLLTLTGDARGTLRNFLRAESGNPRIDFDAEVAWSESRHGHRNAALAHLLADHGRLDNPVPDVLDHYFWQCSLAMNCRDLALAAGFLARHGLRADSSRLLTGSEAKRVNAVMLIGGTYDAAGEFAHRVGLPAKSGVGGGIIAVIPGRCTLCTWGPALDAHGNSIAGITALDTLTTVTGWSIF
>NZ_CP025394.1|WP_104814480.1|470508_470850_-|hypothetical-protein
MLKHLLPAREPAGAPSPGPASSSIEVTPRPVDIKCMGRRYRATGADGTLTITDVTDITRPVRLGTAHPDGAGTWQVRTARRSCRTPARDLADAIALLHEIAWPTRPLWPQGPS
>NZ_CP025394.1|WP_104814479.1|469332_470238_+|isopenicillin-N-synthase-family-oxygenase
MSWRDAIHVAAHLHSSDRPSALDRHALHRAARDVGFIDNLNSPHFRGYTRIGNERTQGLRDWRDQLDISNERPAHVPGPDEPPYWWLEGPNQWPDALPELRGITLAWMNSLSAVAHRLLHELLTAIGGPEDFYDDAFVGKARNHLKLVRYPGRAREGEDQGVGVHKDYGFLTLLLTDEVPGLQVEAPGGAGYIDVPHLPGAFVVNLGELLEVATNGYLKATNHRVVSPLGARERFSAPFFYNPRLDARVAPLPFPGAAEATGVTRDPDNPLFAEFGWNELKGWARAHPEVVKKHHRELRFG
>NZ_CP025394.1|WP_174805616.1|468589_469336_+|ATP-binding-cassette-domain-containing-protein
MPASAAFAPVSLATRDLHLSLGGNPVLRGVDLDVPRGETLCVIGPSGSGKSTLLRTINRLLEPDRGDVLLDGESVLHRDPDLLRRQVGMVFQQFNLFPHMSVLHNLTLPLRKLRGLSREEAEEAAHHQLDQVGLRHKAGERPGRLSGGQQQRVAIARALVMAPQVILFDEATSALDPELVKGVLTLMADLGRAGMTMVVVTHEMGFAREVADRVAFMDRGAVVESGAPDSLFGAPQSPRLRQFLSDVL
>NZ_CP025394.1|WP_104814477.1|467778_468573_+|amino-acid-ABC-transporter-permease
MDQFSTLVDTFFNWGSMRSAVSDLLTTGVPNTLLLSVTSAAIGTVLGLLLAVAGIARARWLRWPARVYTDVFRGLPAAVTILLIGVGLAPEGLTLWGPDPFPLGILALSLIAAAYFGEIFRSGIQSVEPGQLEAARALGFSYASAMRLVIVPLGVRRVLPAWVNQLIALIKDSSLIYFLGLTAGQRDLFRIGQDSAANTGNESALVLAGLFYLVLTVPLTHLVNVIDRQLRDGRRVVEQSTAPAEAEPRPEPVPRTASEGPTHV
>NZ_CP025394.1|WP_104814476.1|466835_467714_+|amino-acid-ABC-transporter-substrate-binding-protein
MRPRRVLVTALTTLVSLASLTACSSTSSGSKASDNPYQLAEPGTIHVGTLSDAPPNVYLKDGRFTGFDNDLFTAVAAKAGLKVQFAATDFSSLLSQVANHKFDVGSSSITITEARKKTVAFSNGYDFGYFGLDVPAGSPVKTFDDLTGKRVVVVQGTVQDDYATKHHLDPVRVPDYNSALNQLKTGTAQAWISPAEIGEKSAADSGGKVVLAQKQLSPAPTAFAVAQDRPQLLAALDKALDEVIADGTWTRLQEQYYPGRAVPEGFKPGGGSVSYPPVTAGGGSPTAASATP
>NZ_CP025394.1|WP_104814475.1|464403_466113_-|ABC-transporter-substrate-binding-protein
MIKSRAAVAAVAIALLTGLTAACGAGGGQGATAGAAFDPNACQGGTLTVLNHRGQGNFDPAELYTSGGGKVPTLTFRTLTTRNHITDGPDSAKVVPDLATNTGEPNQDATVWTYHLRPGLKFEDGTPIRSADIKYGLERSFAPELPGGPPYLRDWLVGGETYQGPYKGGDLASIETPDDSTIVFKLRKPEGDFPFLATATQFAPVPKSKDTGTDYQKHPVSSGPYKVVSNDGGKTITLDRNPSWSRSVDDQRLACPDRIQVLSGLDKSVINQRLAAGTGDDAHAVTTDSNVDASVLAKLNSDSALKSRVVTGYFGETQYLAFNPKVKPFDDVRVRQAIAYAIDRQSVVNAVGGSAVAKPATTFLPDQAAFGHTPYDYFPAGQSGDPAKAKELLAQAGYAGGLTITLDHSTVTGDGSGPEVAAAVQQALGKAGITVKLEGTADDDYQTKYQKPATEPGLFLTSWGADWPSGGPFLAPVFDGRQILADGGNYNSFQLNDPQVNAEIDAANKLTDPAQAAKAWGALDAELGKQAYLVPLYHPVYERLFGKGVKNAYVSQWNGVYDLSRISVK
>NZ_CP025394.1|WP_104820583.1|463368_464379_-|ABC-transporter-permease
MTGPQLPVGAPEQQGAGRSRPERHQTWRRLRADRAATVALVAVTLLVLTAVAAPLISAAEGQDPTTYHNDLVDSATGGVPIGSFGGAGAQHWLGVEPGTGRDVLARLVYGAQISLAVSIGATAVQLTLGVLIGLAAGLGNRAADTVLSRTMDLAIAFPSLVFAVALMAVVPSGFPRPLLLMLVIGVLGWGTTARIVRGQVLTLRGLDYVSAARLAGSTRWRVARREILPALAGPVITYGVLQLPVNVSLEAGLSFLGVGVRPPTSSWGQMLSSATDWFQADPAYVLLPAGLLFVTILSFTVLGDGVRTALDPRARSRLRAGIDPRRGKAGPREAAS
>NZ_CP025394.1|WP_174805615.1|462382_463318_-|ABC-transporter-permease-subunit
MSAVVYVIFYAAPHDPAVLVCGKGCDGTRLAVVRHKLGTDRPLWEQYGQFLRALVAGRSFDTGTGTVRCAAPCLGYSFQSDQPVLELITQRVPVDFSLTLGAMVVWLVLGVGTGLLSALRRGRFSERALTTLTLAGQSTPVFLVGLMAIMLFCSTLQWLPFPSYTAFTADPAQWAANLVLPWVSLALVLSAAYARMTRTSLLETMAEDHIRTNRAYGLTERRIVLGHALRGALVPVVTMLAIDVGGLLGGAMLTESVFGFDGLGRLLVTAVGQTDLPVVVGVTLFAGFFTVAANAAADVLYALADPRVSLA
>NZ_CP025394.1|WP_104820584.1|475218_475518_-|acyl-carrier-protein
MQPPTEQEVLTEITAMLAAVLEEYGLDDAEVTMESRFTEDLELESIDLVTLAGQLQERWGDRINFAEFLAGMELDEIIGLTVGRLVRHVVDRLQTAGRS
>NZ_CP025394.1|WP_104820585.1|475541_480287_-|type-I-polyketide-synthase
MQRAATPVAVVGMAVLLPGAPDLAAYWRNLVDGVDAVTDVPAGRWDTDYYDPGGATGTAAPDRIYCRRGGFVDGLAEVQPTRFGLMPSSVAATEPDQLIALQVAAAAIADAGGPERLPDRDRIGVVLGRGGYLTPGLVRLDQRVRSAHQVVRTLAELLPDLTDSQLEKVRAAFTDRLGPDQPESAIGLVPNLAASRLANRLDLRGPAYTVDAACASSLVAVDQAVGELAGGRCDLVLAGGVHHCHDVTLWSVFAQLRALSPSQRIRPFHRGADGLLVGEGTGVVALKRLADAERDGDRVYAVIRGTGVASDGRTAALASPDPGGQTRAVRAAWRAAGLDPAAPGVLGLLEAHGTATPAGDAAELATLAEVFGPADGAERAVLGSVKSMIGHTMPAAGVAGLVKAALAVHHGVLLPTLHCEDPHPALAGTRFRTISAAQPWETDPAGPPRRAGVNAFGFGGINAHVVLEQAPGRTGPTRAVRRAALSVAEPERVLRLAADGPERLADQLAAEDSALLAAAAAEPGAGAPSCRLAIADPTPKRLALARRAVARGRAWRGRGDVWFTPQPLLAAGGRIAFLFPGLEGEFTPRVDEVADHFGLPRPLPADAAQVGDIGRHGVGVVAVGRLLDTALRRIGVRPDAVAGHSVGEWTAMIAGGLYSGASVDSFLTAFDPDSLRVPGLAFAALGAPADRVLDALATVEGMSEVVLSHDNAPQQSIVCGPEQPVTELVHWFRARGVLGQVLPFQSGFHTPMLAPYLDPIRQAADLFELHRPTVPVWSGTTASPFPPTEAAVRALFVRHLLEPVRFRPLIEAMYAAGFRAFVQVGTGQLASLVGDTLGERAHLAIPANSPHRDGLAQLRRVAAALWVDGAEPDPAALRPAAVRAAAPLRSHPAVPLPGSPAPVDGSGQRPHPAVPLDLGGALVSLDPVALGALRADLASARRTGPDLASLADRSPVAAELNALLRETERAAAELIGAGRPSAVPVVPGGAAAALAGSVAPAAPVVPTAPAVAVGPAAPAVPTVATAPAAPAAAAAPRQALVSRLRVSLDTMPYLLDHCFFRQRPGWPDPLDRWPVVPATTIVQHLADAAERAVPGRLATGLSELRFGQWVPAANPLEVDITLEHAGSGRLAAAFGGFARGVVELTDHHALPPAPWPVDPSAERAPELTAAGLYEQRWMFHGPAFQGLTELTALGPSHVRGVITAPAAPGALLDNVGQLLGYWIMATHTERTVVFPVGIRQLRFYGPPPRPGAELQCHIRITGLTDTVLEADVQLLSGGTVWAEVQGWQDRRFDSHPETRPVERFVERNTLSSPQPGGWVLLHERWPDLASRDLIMRNHLGTAERARYERQPPRGRRAWLLGRIAAKDAVRRLLWQQGEAAVFPAEIEVLNEDSGRPRLAGVHGRTLPELEVSLAHRAEAAVALVRPRRPGGGPGAGIDLEEVVERPAETLRVALGEAELALLAQCRRAHGGSEALWFARFWAAKEAAAKSAGTGLQGRPRDFAVVAAEPSVLTVLAAGPAGPRTHRLRCTGVDSPAGLPERSYVVAWTPADDGPDGPDRDHSDHSDHSESGRDRDERTAAK
>NZ_CP025394.1|WP_104814485.1|480295_487237_-|type-I-polyketide-synthase
MRSAAQSTIAPTALLTDLVIGLTPFQQPDAGLAEAVCRAGALGVLDLGVGDRRAREELATLRGRFTGRFGVRVGPDCRLDPAELRSPGGAGPDTVVLAEGAPGWDAAELAGGYRLLVEVTDLAQALAAVRAGAHGLIARGSESGGPVGELSTFVLLQHLLAVPEIEVPVWACGGIGLHTAAAAVAGGAAGVVLDSQLALLAESAAPQEIAAAVRGMDGSETAVVDGRRVLQRASGGSPGQELMVGQDGFLAARFAERWRTVGAAVRAVRDAVLDVLRAAAEPGAASALLGPGAPMSRALGTGLPVVQGPMTRVSDQPAFAAAVAEADGLPVVALALAGAGQTRELLAQTGAALGKRPWGVGVLGFAPEEVRSAQLAEVLAARPSHAVIAGGRPSQARVLEEAGIRTFLHVPSPGLLKQFLEDGARRFVFEGSECGGHVGPRHSFPLWEAQLAVVEDFLAAARDSPQLELLFAGGVHDERSAAMVAALAAPLADRGVAAGVLMGTAYLFTEEAVAHGAVQPQFQRQVLAARGTELLQTAPGHATRCVASPFTAEFEQARERLRAEGVPEREVWEQLERLNVGRLRIASKGLDRVAGALEEVDEQGQLERGMFMAGQVAVLRSATTTLAGLHIAVGTGAAGFLAARAADLVERLGPAPEPAAEPESAPLEIAVIGMAGMFPGAPDLPAFWANVVGGVDAVTEVPAERWDPALYHSADGGPGTTPSKWGGFLPRIPFDPLAYGIPPTALGSIEPVQLLALEAARRALLDAGYDGGGAEGGREFDRSRTSVVFGAEAGSDLSNAGVLGAVLPAYLGKVPDAIAEQLPKLTEDSFPGMLSNVISGRIANRLDLGGANFTVDAACASSLAALDVACKELASGASDLALCGGADLHNGINDFLLFASVHALSPTGRSRPFDASADGIALGEGVGCLVLKRLADAERDGDRVYAVVQGVGSASDGRSLGLTAPRPEGQRLALERAYRSAGTSPARVGLVEAHGTGTVVGDRTELAVLTEVFAEDGATPGSCALGSVKSQIGHTKCAAGLAGLIKASLALHTGIKPPTLHLERPNAAWEAGGSPFVFHAEACPWAAAPAERVAGVSAFGFGGTNFHAVLRGYDGPTPVHGLQEWPAELFLFRGTDRERALRGVADLLRWADADGSPWRLRDLALAASRRAESGRGPVQIAVVASDVAELVRLLRAAEAGADVDGLYLAEEADEQPGEVAFLFPGQGSQRPGMFAELFAAFPGVQRHLRLGAAYADTLYPPLAFTPEAREAQRTAITDTRVAQPVLGMAGLAAFELLALAGVSPQLAGGHSYGELVALCAAGALAAEDLPSLGADRARAILGAVGAGGDPGSMAAVAAGAEEVERVLAAGGLAGRVVAANHNAPRQTVVSGATPELATAIGLLREAGYGVKKLPVACAFHSPLVAGAGECFAEALAARTVRAPEFPVFANRTAAAYPADPAGVRAELEAQIGAPVRFVAQVEAMYEAGARVFVEAGPGSVLTRLVSAVLGDRSHRAVPLEGRRRGLPGFLDALAALAVAGVPVRTDRLYRGRDAVDAGRARPPRPPGWTVDGQLVRTAAGELLPGALAPARPVPEALMTAQAPNPNGDALVSEFLRSSRELIAAQRDVLMTYLGGTGQALAPIASVPPVAVQLPVATAVPVPELPAIAARPEPVVVAPVTAVVPVAAVAGPVGEEDVLRAVVEVIGERTGYPADMIEPGLDLEADLSIDSIKRTEIIGQLARRLGDAQGLGALGGLADEQVEELSRARTAADITAWLTTRLGAPAPEPASAPVPAPEPLAASVPIAAPEARHLDAGTPVTEPPVTGHEPVRLVFEAVPLAEPARTPESLLGRRFALLGEDGHGVGPALAARLAAAGAQLTVLPTGHELSSADGPLDGVLLLDPLAEHGAPVLPGTVPVLQAALALAPRWLYAVRPASRPGPGRADGLRGLFRTLAREYPDSSVRLVELDPADPARAADLLLADLVAEDREPVVLHGPAGRQGLALVERGLGLLGSTGAGPAGEGVAEAAALRLDQEAVVLLVGGARGITARFAATLASASRCRLELLGRTAPPEGLEDPATAAARDRSALRAALARQGVPLPEVDAAASRLLAGREVAATLDELSALGSQARYRAVDAADPAALRQAVKEVYAEYGRLDGVVYAAGVIEDRVLAEKDPESFRRVFATKADGARALLDALAELPAGPGFTVLFGSIAAALGNRGQADYAAANDALEELAARWSDQTGRRALTVHWGPWAPAGAHGGMVSEELARDYVRRGVKLIDPEAGTLALLRELAWGERSERAVVYTASGW
>NZ_CP025394.1|WP_104814486.1|487547_488561_-|LacI-family-DNA-binding-transcriptional-regulator
MTDEPTRRRPTLDEVAERAGVSRSAASRALNNGPNVSRAKREAVLRAIKELGYVPNPTARALATQQAGAVALIISGEDPAVLADPFYGQVIAGASTVLEETDLHLMLCLATSARGQVRVKQLLQARAVDGVMLMSLRGDDPLARLALEADVPVVFGGKPLHGQVPFYVDVDNAHGARQATDHLISLDRTRIATLTGPLDTDVGLARRRGYLEALTLAGLPWRAEEAGDFTERGGIAAMEALLARHPDLDAVFAANDNMAAGALRVLARAGRAVPAEVAVVGFDGLAISEITEPPLTTVHQPILNIGREMTRMLLALIAGERPSPLILPTTLVRRESA
>NZ_CP025394.1|WP_104814487.1|488771_489749_+|glycoside-hydrolase-family-6-protein
MRRSRRSTALLIAPALTALLVAVHPGTAYAADPTTMTNGFYTDPNSTPQQWVNANRGDGRAAAVQASIANVPAARWFGNWSGTIGTATGAYVGAAAASGKLPILVAYDIPSRDICAGQSGGGAGSVADYNTWIAAFASGIGNRPALVVLEPDALGHESCMTPAQISDRNGMLRNAVAQFTAKAPNTWVYLDAGNPGWLSATAMAKLLADAGVAGAHGFSTNVSNFFTTAQNTTYGNAVSAALKSSYGYAKPYVVDSSRNGNGSDGTWCNPAGRRLGTPTSRAGGGPEMLLWIKTPGESDGNCGTGAGTTAGQFVPEIAYKLIYGY
>NZ_CP025394.1|WP_174805617.1|490054_491116_+|glycoside-hydrolase-family-6-protein
MAGGRLVHRRHPRPGGGPGPHAGAPRRPHRHRPGHRGLRRPAAGLLPVLQRRCAVRRRLPGLDLGARPGHRPAAGRDRPRAGRPGQPARRLLPDHRPHRRAHGRPAGRLADLRHGIDALEQQPNTVVYLDAGNSHWQSVGNAAKRLLDAGVEHAQGFSLNVSNFFATGPSDRYGTWVSDCLWFATKGPDYARGHTDYCASQYYSPAAPNDGQPGDSVDADDPSTWHWTDDWFRQNVGTPPLDQLTHFVVDTGRNGQGAWTPPPGKYGGDPQIWCNPPGRGIGDRPTAATGVPLVDAYLWIKTVGQSDGACNRNIPGGTVDPEYGTVDPAAGTWWPAQAMTLVQNANPPLTPPH
>NZ_CP025394.1|WP_104814488.1|491253_492219_-|Gfo/Idh/MocA-family-oxidoreductase
MTKDRTVRIALAGGGAFGAKHAAALRRIEGVEVTAVVSSSLDSARKFAAEQGVGRGVATLEEALALEEVDAVILATPTPMHAAQTLACLEAGKHVQVEIPLAASLGDAEACLAAQQRTGLVAMVGHTRRFNPSHQWVRRRIEAEQFRIQQMDVQTYFFRRENLNALGQQRSWTDHLLWHHAAHTVDLFAHQTGSPIVQAHAIQGPIHPELGIAMDMSIQLRASSGAICTLSLSFNNDGPLGTFFRYIGDTGTYLARYDDLFTGKDEPIDVSGVDVSMDGIELQDREFVAAIREGREPNSSIAQVISCYRTLASLEAQLATA
>NZ_CP025394.1|WP_104814489.1|492220_493528_-|protocatechuate-4,5-dioxygenase-subunit-alpha
MSLDKSYKLVPGTTVFDAEQSAKGYHLNQFCMSLMTAENRQSYLADERAYLDAWPLREEQKQALLDRDLNAAIREGGNIYFLAKWGATLGLSFQQMAGSMTGMTEQDYREMMVAGGRSITGNRIDHAVLEAAHADRTPPAEHATITGAVFTSHVPAIGAAMDHHKTEEPYWQPVFGGYAYSRQWVRDNPPDVVVLVYNDHATAFDQSVVPTFVLGTGAVYPTADEGYGPRPVPGVQGHPELAAHIAHSLIRDDFDLTLVNEMSVDHGLTVPLSLMFGEVEAWPCRVIPFHVNVVQYPVPSGDRCFRLGQALRRAIESYDRPLNVQVWGTGGMSHQLQGPRAGLINRAWDNAFLDRLVEDPAGLARVPHLEYVEEAGSEGIELVMWLIARGAMSDIDGSGETELKHRFYHVPASNTAVGHLILENHPRAAVPAAKE
>NZ_CP025394.1|WP_104814490.1|493555_494476_-|amidohydrolase-family-protein
MTTSFEKTPGWLDWYAGPSRPAYQLPPGAVDAHCHVFGPGAEFPYAPERKYTPCDASKEQLFALRDHLGFARTVVVQATCHGADNSAMVDALRASGGLARGVATVRPEVTDAQLRELHEAGVRGVRFNFVKRLVDAAPRQDLREVVERIRPYGWHVVVYFEAADLAGLREFLLSIPVPLVVDHMGRPDVAKDPDGPEFEAFLSFLRARPDIWCKVTCPERLSVSGPPALDGERAAYRDVVPFARRVVEEFPDRVLWGTDWPHPNLTDHMPDDGLLVDFLPRIAPTPQLRQRLLVDNPMRLYWPDPH
>NZ_CP025394.1|WP_104814491.1|494478_495168_-|4-carboxy-4-hydroxy-2-oxoadipate-aldolase/oxaloacetate-decarboxylase
MEHTEIGVVHTSVTRAAPEAVAALSAFGVATIHEAMGRVGLMRPYLRPVYPTARLCGTAVTVLLQPGDNWMLHVAAEQIREGDVVVAACTTESEDGFFGDLLATSFRSRGCRGLVIDGGVRDVADLAEMDFPVFARAVNARGTVKATLGSVNVPVVCGNALVRPGDVVVADADGVVVVPRERAAEVAAAAAAREAAEAGKRARFHAGELGLDIYDMRGPLGALGLRYED

Crispr_ID: NZ_CP025394_3

• CRISPR_ID: NZ_CP025394_3
• CRISPR_location: 1319401-1319558
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_3

Consensus_repeat	Method
CCCTCACCGGGGAGGCCAGCGCATGAGATGGCTACTGCTGTACGCCCGCTC	CRISPRCasFinder

spacers of NZ_CP025394_3

>3.1|1319452|56|NZ_CP025394|CRISPRCasFinder
CCGCCAGGTGCCCGCCTCGGCCACCGCGAACCTGCTGCCCGCCCCGGCCACCTGCA

CRISPR arrays and Neighbor proteins around NZ_CP025394_3

CRISPR arrays

The CRISPR arrays of NZ_CP025394_3

>merge|NZ_CP025394|3|1319401-1319558|CRISPRCasFinder
CCCTCACCGGGGAGGCCAGCGCATGAGATGGCTACTGCTGTACGCCCGCTCCCGCCAGGTGCCCGCCTCGGCCACCGCGAACCTGCTGCCCGCCCCGGCCACCTGCACCCTCACCGGGGAGGCGAGCGCATGAGATGGCTACTGCTGTACGCCCGCTC

>NZ_CP025394|3|3|1319401-1319558|CRISPRCasFinder
CCCTCACCGGGGAGGCCAGCGCATGAGATGGCTACTGCTGTACGCCCGCTC	CCGCCAGGTGCCCGCCTCGGCCACCGCGAACCTGCTGCCCGCCCCGGCCACCTGCA
CCCTCACCGGGGAGGCGAGCGCATGAGATGGCTACTGCTGTACGCCCGCTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104815051.1|1320656_1322141_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224983
NZ_CP025394.1|WP_104820677.1|1324796_1325699_-|C1-family-peptidase	unknown	unknown	gnl|CDD|239110
NZ_CP025394.1|WP_104815044.1|1309952_1311161_-|acetylornithine-transaminase	unknown	unknown	gnl|CDD|235112
NZ_CP025394.1|WP_104815054.1|1326735_1327107_+|hypothetical-protein	unknown	unknown	gnl|CDD|378915
NZ_CP025394.1|WP_104820678.1|1327319_1328546_+|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl|CDD|274452
NZ_CP025394.1|WP_104815055.1|1328550_1329141_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379240
NZ_CP025394.1|WP_104815045.1|1312111_1313290_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl|CDD|235441
NZ_CP025394.1|WP_104815048.1|1315353_1315554_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104815043.1|1306496_1307690_-|argininosuccinate-synthase	unknown	unknown	gnl|CDD|234785
NZ_CP025394.1|WP_104820672.1|1307852_1309157_-|MFS-transporter	unknown	unknown	gnl|CDD|340883
NZ_CP025394.1|WP_158702049.1|1322298_1324032_+|AMP-binding-protein	unknown	unknown	gnl|CDD|171961
NZ_CP025394.1|WP_104815049.1|1315949_1316747_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NZ_CP025394.1|WP_104815056.1|1329291_1329918_+|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319790
NZ_CP025394.1|WP_158702048.1|1314702_1315032_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP025394.1|WP_104820675.1|1319617_1320538_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378890
NZ_CP025394.1|WP_104820673.1|1309370_1309871_-|arginine-repressor	unknown	unknown	gnl|CDD|235116
NZ_CP025394.1|WP_104815046.1|1313286_1314315_-|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl|CDD|234761
NZ_CP025394.1|WP_104820676.1|1324100_1324643_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP025394.1|WP_104815053.1|1326157_1326739_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP025394.1|WP_104820674.1|1311157_1312033_-|acetylglutamate-kinase	unknown	unknown	gnl|CDD|234869

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104815051.1|1320656_1322141_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	8.09079e-120
NZ_CP025394.1|WP_104820677.1|1324796_1325699_-|C1-family-peptidase	gnl|CDD|239110	cd02619, Peptidase_C1, C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some exceptions like cathepsins B, C, H and X, which are exopeptidases. Papain-like CPs have different functions in various organisms. Plant CPs are used to mobilize storage proteins in seeds while mammalian CPs are primarily lysosomal enzymes responsible for protein degradation in the lysosome. Papain-like CPs are synthesized as inactive proenzymes with N-terminal propeptide regions, which are removed upon activation. Bleomycin hydrolase (BH) is a CP that detoxifies bleomycin by hydrolysis of an amide group. It acts as a carboxypeptidase on its C-terminus to convert itself into an aminopeptidase and peptide ligase. BH is found in all tissues in mammals as well as in many other eukaryotes. It forms a hexameric ring barrel structure with the active sites imbedded in the central channel. Some members of the C1 family are proteins classified as non-peptidase homologs which lack peptidase activity or have missing active site residues.	2.20375e-23
NZ_CP025394.1|WP_104815044.1|1309952_1311161_-|acetylornithine-transaminase	gnl|CDD|235112	PRK03244, argD, acetylornithine transaminase.	0
NZ_CP025394.1|WP_104815054.1|1326735_1327107_+|hypothetical-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.0016767
NZ_CP025394.1|WP_104820678.1|1327319_1328546_+|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl|CDD|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NZ_CP025394.1|WP_104815055.1|1328550_1329141_-|GNAT-family-N-acetyltransferase	gnl|CDD|379240	pfam13527, Acetyltransf_9, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.93066e-08
NZ_CP025394.1|WP_104815045.1|1312111_1313290_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl|CDD|235441	PRK05388, argJ, bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ.	0
NZ_CP025394.1|WP_104815043.1|1306496_1307690_-|argininosuccinate-synthase	gnl|CDD|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_CP025394.1|WP_104820672.1|1307852_1309157_-|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.07039e-16
NZ_CP025394.1|WP_158702049.1|1322298_1324032_+|AMP-binding-protein	gnl|CDD|171961	PRK13295, PRK13295, cyclohexanecarboxylate-CoA ligase; Reviewed.	5.53873e-104
NZ_CP025394.1|WP_104815049.1|1315949_1316747_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	7.75935e-17
NZ_CP025394.1|WP_104815056.1|1329291_1329918_+|HAD-IA-family-hydrolase	gnl|CDD|319790	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive. This family includes the N-terminal phosphatase domain of human soluble epoxide hydrolase (sEH). sEH is a bifunctional enzyme with two distinct enzyme activities, the C-terminal domain has epoxide hydrolysis activity and the N-terminal domain (Ntermphos), which belongs to this family, has lipid phosphatase activity. The latter prefers mono-phosphate esters, and lysophosphatidic acids (LPAs) are the best natural substrates found to date. In addition this family includes Gallus gallus sEH and Xenopus sEH which appears to lack phosphatase activity, and Escherichia coli YihX/HAD4 which selectively hydrolyzes alpha-Glucose-1-P, phosphatase, has significant phosphatase activity against pyridoxal phosphate, and has low beta phosphoglucomutase activity. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.68576e-26
NZ_CP025394.1|WP_104820674.1|1311157_1312033_-|acetylglutamate-kinase	gnl|CDD|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	3.47498e-150
NZ_CP025394.1|WP_104820675.1|1319617_1320538_-|AraC-family-transcriptional-regulator	gnl|CDD|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	1.03976e-31
NZ_CP025394.1|WP_104820673.1|1309370_1309871_-|arginine-repressor	gnl|CDD|235116	PRK03341, PRK03341, arginine repressor; Provisional.	1.99398e-79
NZ_CP025394.1|WP_104815046.1|1313286_1314315_-|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl|CDD|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	1.36735e-180
NZ_CP025394.1|WP_104820676.1|1324100_1324643_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.82557e-18
NZ_CP025394.1|WP_104815053.1|1326157_1326739_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.49948e-19
NZ_CP025394.1|WP_158702048.1|1314702_1315032_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.00377e-09

Protein sequences

>NZ_CP025394.1|WP_104815049.1|1315949_1316747_+|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MQKTLELPDLLRLIDERSTAFRAAVAAAPSLDVQVPTCPEWTLFDLAEHLGGGDRFWAAIVSAGPADAPPAEATAARAALEVPREREALLGWLATSTQQLLSALREAGPESGCWTWWPASQSPQNSGGVARHRVQETAVHTYDAQVTAGTPQPLPAEVALDGVEEFLFTCCATASAWPHKPTSFDFHAAEGRSWRLTVDGDGARSTRIPAPGATTSEGSDAVGISIHGTASELVLFCYDRIPTDSLHVDGDAGLIDLLRAWEPGQ
>NZ_CP025394.1|WP_104815048.1|1315353_1315554_+|hypothetical-protein
MAIPLSQATVGPLSAAIGVRTTLFGAAVVVLGCVGAMLAVRDVRALRITTASPAARPVSTPAPAAA
>NZ_CP025394.1|WP_158702048.1|1314702_1315032_+|MFS-transporter
MVAVRSLFDVAFVLFDVAFVLFGGVLAGRLPRRLVPVGPSVLSTAGQGAPAALVLIHHATIPWILALSVCDGTFAAFAMPASSALLPQTVPDELRLQANALNRTARTAR
>NZ_CP025394.1|WP_104815046.1|1313286_1314315_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MALRVAVAGASGYAGGEALRLLLGHPEAEIGVLTGGSNAGARFGELQPHLLPLADRVLEPTTPEVLAGHDVVFLGLPHGQSAAVAEALGEDVLVVDCGADFRLKDAAVWEKFYGSPHAGTWPYGLPELPGHREALRGTKRIAVPGCYPTAVTLALFPAYAERLVEPEAVIVAASGTSGAGKAAKPHLLGSEVMGSMSPYGVGGGHRHTPEMAQNLLPVAGEPVTVSFTPTLAPMPRGILATCSAKAKPGVSYEAVRAAYEKAYSGEPFVRLLPEGQWPQTSSVYGSNAALVQVALDEHAGRVIVVSAIDNLVKGTAGGAVQSMNIALGLPEELGLPLNGVAP
>NZ_CP025394.1|WP_104815045.1|1312111_1313290_-|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MSTESSSNVGVTAAKGFRAAGVTAGLKASGLPDLALVVNDGPSYAAAGVFTSNRVKAAPVLWSEQVLKGGQVAAVVLNSGGANACTGPLGFQDTHATAEKVAEELKISAGEVAVASTGLIGVRLPMDLLLPGVEQAAQGLSETGGEQAAIAIKTTDTVHKTAQVTSPAGWTVGGMAKGAGMLAPGLATMLVVLTTDAALLAEDLDAALRAATRTTFDRADSDGCMSTNDTVLLLSSAASAVVPDTAEFAAAVETVCADLARQLIGDAEGASKDIRIDVTGAATEDEAVDVGRTIARNNLLKCALHGEDPNWGRVLAAIGTTKAAFDPDQLDVAINGVWVCRNGSVGEDRDLVDMKGREIVITADLKAGQAEATVWTNDLTADYVHENSAYST
>NZ_CP025394.1|WP_104820674.1|1311157_1312033_-|acetylglutamate-kinase
MTLIEALPWLERFHGKTVVIKFGGNAMVDEELKAAFAQDVVFLRYAGLHPVVVHGGGPQISKQLEKLGLESSFTNGLRVTTPETMDVVRMVLAGQVQRELVGLLNSHGPFAVGMTGEDAHTMTAVKRYAVVDGEQVDIGLVGDIVNVEAGAVKALIADGRIPVISSIARGGDGHVYNINADTAASALAVALGAEMLVVLTDVEGLYADWPNSDDVISQLSADELDELLPTLASGMLPKMEGCLNAVRSGVGTARVLDGRVPHSLLLEIFTDEGIGTMVVPDTDTIVTRGLA
>NZ_CP025394.1|WP_104815044.1|1309952_1311161_-|acetylornithine-transaminase
MTTNEQATQRWQHALMNNYGTPRLPLARGAGSTVWDEDGKPYLDLVCGIAVNALGHAHPAVVEAVSRQIGELGHVSNLFQAEPTVRLAERLLALDERPARVFFCNSGAEANEAAFKISRLTGRTHLVSLEGAFHGRTMGSLALTAQPAKQTPFLPLPGEVTHVPFGDIEALRAAVTTETAAVFLEPIQGENGAIPLPEGYLKAAREITRATGTLLVLDEVQTGIGRTGHWFAHQAYEGVEPDVITLAKGLGGGLPIGAVIAYGAAAELLQPGHHGTTFGGNPVVAAAALAVLDTIEGEGLLAQVRKTGELLRSGIEAIGSPLVSHVRGAGLLLGIVLTQPLAGQVQAAAQEAGFLVNAAVPDAVRLVPPLVLTEAEADRFLAALPGILRAALDAAPDAKPRG
>NZ_CP025394.1|WP_104820673.1|1309370_1309871_-|arginine-repressor
MPQTRTARHRRIVDLLTRQPVRSQSQLAKLLADDGLVVTQATLSRDLDELGAVKIRNRDGALIYAVPAEGGDRTPRAPMGESASEGRMARLAGELMVSATASGNLVVLRTPPGAAQFLASAIDQAEVFEIIGTIAGDDTVLLISRDPAGGQALADHLMQLAQAKAQ
>NZ_CP025394.1|WP_104820672.1|1307852_1309157_-|MFS-transporter
MLLIGFAGLAVVPTLPTAARELDGVALFPVVAGCFVAANLFGGVLGGHWADRAGAGRPLAVGMLLSVLALLVAGTSGTIWQLAAGRLVDGLAAGLVSVSVTTAIGRRYPERLRAGMLALLAAAWILPSLIGPPLAALVAAWSSWRTVFLGLAALTALPALALIAVLRRTGEQEPPAEPRADAEPEVSPKDDRVPVGAAAGLSAGAAVCQYGASGWSTGQLVALVVGGGLLGWFGPKVLPGGVGRAVRGLPVTVLLRGLSAGAFFTVEALVPLVLVTERQVPALVTGVGFTGAAVLWTVASWAQSKLRAAGHRPVVAGAGVLAVAVGLASAACLPGVSPLLGVAALPVAAVGMGFLTPALTVLSLRHGTRHGYATGAMQTAQNLGQAALLALASLVLNAVAALGGSALPGYAAAVALLLVPVALVAALAGRAKAV
>NZ_CP025394.1|WP_104815043.1|1306496_1307690_-|argininosuccinate-synthase
MAERVVLAYSGGLDTSVCIGWIAEETGAEVIAVAVDVGQGGEDLSAIRQRALDCGAVEAEVADAREEFADEYCLPALKANALYQGQYPLVSALSRPAIVKHLVAAAKKHGATTVAHGCTGKGNDQVRFEVGIQSLAPELKCIAPVRDYAMTRDKAIAFAEAKNLPIVTTKKNPYSIDQNVFGRAVETGFLEDIWNAPIEDVYEYTQNPATPREADEVVITFEAGVPVAIDGRKVTVLQAIEELNKRAGAQGIGRLDMVEDRLVGIKSREIYEAPGAIALITAHQALENVTVERELARYKRQVEQRWAELVYDGLWFSPLKRALDGFVNEANQAVSGDIRMVLHGGRAVVNGRKSDQSLYDFNLATYDTGDTFDQSMSKGFIEIFGMSSKIAARRDLA
>NZ_CP025394.1|WP_104820675.1|1319617_1320538_-|AraC-family-transcriptional-regulator
MGSLIRATNLHGYGALVRELGGDPGPLLRRYGIRPGVELVEDAFVSYGPFARLLETTAEELDCPDFGLRLSAWQGLGILGPVAVIARNSATVLGAFAEIGRYLHVHSPALRLSVAGPGESGYRAGSTTFHFAIEERGLPYVAQSYELSLANGARIGRLLAGHEMRPRVVAFRHGRCGPLAAYEELFGAPVLFEQDWCGIELGDTDAHRPVDNADPATRRIVARYLETTHRAGEELAPLVAELTRRLLPTGTCSAEAIAGHLGLHPRTMQRRLAEEATTFAAILDHERAQQAGRRWSRPGSRRRRPA
>NZ_CP025394.1|WP_104815051.1|1320656_1322141_+|NAD(P)/FAD-dependent-oxidoreductase
MTSNHTNVLVIGAGISGIGVACRLRRELPGREFAILERREAIGGTWDLFRYPGVRSDSDMFSFGYEFRPWNELKVLADGRSIREYVAATAREYGVDKSIHYGLKVVAADWSSERQRWTVTALREATGETETWTCSFLVTCTGYYDYDRGYRPEFPGADRFEGELIHPQHWPAGFDHAGKRVVVIGSGATAVTLVPAMAETAEHVTMLQRSPSYVFSLPSVDRITATLKKFLPADLVHRMTRRRNIVVQQAMFKAARRFPGPVRKLLLAGVRRGVGPEFDLSHFSPKYAPWDERLCAIPDGDLFTALRTGRASVVTETIDTFTPTGIRLASGRELPADVIVTATGLNLQALGGAAVSVDGVPRDLHEVCTYKSVLLEGLPNLAWVFGYTNASWTLKVDLAAGYLVRLLGHLDRTGQAVATPVDHAANATTEGVVDELSSGYIQRAKGIMPRQGRDFPWRMVMDYRHDRKALLSDPIADGILEFTPATTPSPATSA
>NZ_CP025394.1|WP_158702049.1|1322298_1324032_+|AMP-binding-protein
MKELAELRPAQDAVREHLATGVWRTTGPLADLRHWRDETPDAPAVIAHSATGRHELTYRQFADQVQGFAAALAELGVRAGEAVLVQLPNVWQVGALMLACMRLGAVVAPVMMTLGPRELERVLARLGAGVCITTGEWAGARHAEAVAEMTPRLTELRHRVVLDPAGAPAGSVDFTAFFEDPDRTSALGGTTAELLEDAPAEDPDRVAMVLFTSGTSGEPRGVLHTANTLYAGCSVVASAEGFGPTDRFYATQAVTHLFGGMYSILLPLLVGGTSVLVDRWEPAAVLDLLGESRPTVLAGAPPFVAALLAEAEQRGSAAPKLPLRMVLSGATTVPAQLVAGVPHCWGVPLRTVWGMTEVPGHTWTRHDDPPLWGSRSDGRPGAALELDFRTEDGAVPTAEQPARLFVRGGGLCLATFGRDGGELRVLADQDGGWYDTGDLAVPDGRGGLRLFGRAADRIGGSFMIPVADVETELLAHPGVGDVALVGYRPREDEELACAVVVPSPGAGAGAGSGAGAGGALTLAELRSFLTGRGMTDWYQPSRLELVSELPRNAIGKVRKDLLRAQLAAGEVANSLAE
>NZ_CP025394.1|WP_104820676.1|1324100_1324643_+|GNAT-family-N-acetyltransferase
MELDLAAAAGPTPEVIRTDRLDLLPLTVGHAEEMAAVLDDPSLHTYIGGKPATVATLRSRYERMTAGSGDPAVGWLNWVVRLRAEHRLTGTVQATVTTTPATATAPVTRSAELAWVVGTPWQGRGIATEAALGLADWLRTHGVPDLAAHIHPEHRASAAVAAAIGLTPTDTWQDGERRWH
>NZ_CP025394.1|WP_104820677.1|1324796_1325699_-|C1-family-peptidase
MALGLTAALALSGSLVFTTTATAVTAAPAGHHVRHHHYATGLNLAALKSHKAAVRPAAAAATSRALAALAPHARPGYAPASADLTNYALSPGDQGQVGACVTWATGYTGYGILMNEQGISGAPMAPMYIYAQIAQGNDQGTYASVALPMEQQQGIDTQSDYWQGTSDYTTQPDANEVANAANYKLSGFVQLPNSGGSARSAIEDAISQGEPVPIGFEVQQSFMDLNSQTASDYSYTPGDSGSDPVVGGHEITIVAYNEQGVTIENSWGSSWGNGGFANLPWSFFDAGVVDEVNAMGKLAS
>NZ_CP025394.1|WP_104815053.1|1326157_1326739_+|MarR-family-transcriptional-regulator
MKGVHKSDEGLATDANGLRFDPGVRSAMAGFAVDGDTAALETAAAVRAAAQSMDKLRGQGAGGRGLSAGAMDVLVRLTSLHQPEIGLHIGELARAGGVSSRNVTGLVDTLERDGLVRREPDPHDRRSVRVVATPAGTAWLAAFREPTRRAMSAVFRGFTHAELDTFRDFCLRLVENQRRLDHHLAHRPEGKTP
>NZ_CP025394.1|WP_104815054.1|1326735_1327107_+|hypothetical-protein
MTTRQTVRAYHEARFRGDVTAAAALTGAGFTFRSPFVTSDSPTGHLDGIDGLLSIVTGVELRSELYGEDEAVLVYDVHTASPVGTQRTAEHFRLRDGRITAIELIFDGAPWQALMAAAGPTTT
>NZ_CP025394.1|WP_104820678.1|1327319_1328546_+|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MQEQAKVVVTGLGATTPLGGNVADTWAGLLAGRSGISAIEEEWAAGLPVRIAGQLAVEPSTQLDRVLARRLDRCEQVALVAAREAWADAGAPEVVPERLAVVIGTGTGGVLTLLGQDDVLEAAGSRRVSPHTVPMLMANGPAAWVAIELGAQGGAHTPVSACASGAEAIALGLDLIRLGRADVVVAGGAETSICPITLAGFAQAKAHSTRNEDPTRASRPFDVDRDGFVIGEGAALLVLERAEHAAARGARAHATLAGAAVTSDAHHITAPHPDGQIRAIRRALAEARLSPAEVSLVQAHATSTPPGDLTEARSITAAIGTHPAVTATKSMTGHLLGAAGAVGALATVLALRDGVIPPTANLDTLDPEVDLDIVTGTARRARLTAAVSNSFGFGSHNATLVLTPSPSV
>NZ_CP025394.1|WP_104815055.1|1328550_1329141_-|GNAT-family-N-acetyltransferase
MPDHTTIRAYRPADERSWLHCRVLSFLDTAYFDNVLRERPPVVPPGRGLVAVDPDGAVLALLDVSVTGSLATIESVAVRPEHRRRGLATALLAAWLAEVPAGVDTLDAWTRDDPGTLDWYRAAGFAESEHFLHVYADLRSHPEEPDRAIGARRPGLRPITLFLSAPLAEAARLRGEFGRVHVCRRFSRPLTRSVAG
>NZ_CP025394.1|WP_104815056.1|1329291_1329918_+|HAD-IA-family-hydrolase
MVTGQGASRPFDAVLCDLDGVVRFFDHREVARLERAAGLPAGAAFRAAFRPGVGDRLVLGALDRVTWTAALADGLAPLDAERAGELARAFAHSPAWADETAVALLRRARAHVPVLLVTNATVWLEEDLAALGLTDLADQVVNSARVGLAKPDPALYHLAADRVGLAPDRCLFVDDSPKNVAAAAGLGMRAVLHRTPADLATALADLWS

Crispr_ID: NZ_CP025394_4

• CRISPR_ID: NZ_CP025394_4
• CRISPR_location: 1767061-1767255
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP025394_4

Consensus_repeat	Method
GGCGTCGCCGCCGACCGCACCGGC	CRISPRCasFinder

spacers of NZ_CP025394_4

>4.1|1767085|18|NZ_CP025394|CRISPRCasFinder
GTCCATGCCGCCGCCAGC
>4.2|1767127|18|NZ_CP025394|CRISPRCasFinder
GTCGCCGCACATCGACTC
>4.3|1767169|21|NZ_CP025394|CRISPRCasFinder
CCAGCCGTCACCGTCGGCGGT
>4.4|1767214|18|NZ_CP025394|CRISPRCasFinder
GTTCTGGGTCATCGACTC

CRISPR arrays and Neighbor proteins around NZ_CP025394_4

CRISPR arrays

The CRISPR arrays of NZ_CP025394_4

>merge|NZ_CP025394|4|1767061-1767255|CRISPRCasFinder
GGCGTCGCCGCCGACCGCACCGGCGTCCATGCCGCCGCCAGCCGCGTCGCCGCCGACCGCGAAGGCGTCGCCGCACATCGACTCGGCGTCGCCGCCGACCGCAGCGGCCCAGCCGTCACCGTCGGCGGTGGCGTCGCCGCCCACGGCACCGGCGTTCTGGGTCATCGACTCGGCGTCGCCGCCGACGGTGTAGGC

>NZ_CP025394|4|4|1767061-1767255|CRISPRCasFinder
GGCGTCGCCGCCGACCGCACCGGC	GTCCATGCCGCCGCCAGC
CGCGTCGCCGCCGACCGCGAAGGC	GTCGCCGCACATCGACTC
GGCGTCGCCGCCGACCGCAGCGGC	CCAGCCGTCACCGTCGGCGGT
GGCGTCGCCGCCCACGGCACCGGC	GTTCTGGGTCATCGACTC
GGCGTCGCCGCCGACGGTGTAGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_158702082.1|1764643_1766425_+|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379258
NZ_CP025394.1|WP_104815373.1|1781145_1781691_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
NZ_CP025394.1|WP_104815368.1|1770666_1771389_-|HD-domain-containing-protein	unknown	unknown	gnl|CDD|213552
NZ_CP025394.1|WP_158702081.1|1763872_1764328_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|376300
NZ_CP025394.1|WP_104815363.1|1766485_1766962_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP025394.1|WP_104815372.1|1780339_1781026_+|Type-1-glutamine-amidotransferase-like-domain-containing-protein	unknown	unknown	gnl|CDD|153240
NZ_CP025394.1|WP_104815355.1|1754796_1755417_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|172294
NZ_CP025394.1|WP_104815359.1|1760415_1761828_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224169
NZ_CP025394.1|WP_158702083.1|1783172_1784762_+|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl|CDD|259922
NZ_CP025394.1|WP_104815360.1|1761973_1763062_+|exo-alpha-sialidase	unknown	unknown	gnl|CDD|374209
NZ_CP025394.1|WP_104815371.1|1778519_1779188_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104815374.1|1781763_1783074_-|MFS-transporter	unknown	unknown	gnl|CDD|340887
NZ_CP025394.1|WP_104815361.1|1763351_1763768_+|TOBE-domain-containing-protein	unknown	unknown	gnl|CDD|182640
NZ_CP025394.1|WP_104815369.1|1771514_1772276_-|pirin-family-protein	unknown	unknown	gnl|CDD|380375
NZ_CP025394.1|WP_104815358.1|1758265_1760266_+|S8/S53-family-peptidase	unknown	unknown	gnl|CDD|173788
NZ_CP025394.1|WP_104815370.1|1772354_1775786_-|error-prone-DNA-polymerase	unknown	unknown	gnl|CDD|235553
NZ_CP025394.1|WP_104815356.1|1755582_1757094_+|amino-acid-permease	unknown	unknown	gnl|CDD|132469
NZ_CP025394.1|WP_104815366.1|1769251_1770028_+|TIGR03084-family-protein	unknown	unknown	gnl|CDD|274423
NZ_CP025394.1|WP_104815365.1|1767598_1769134_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341283
NZ_CP025394.1|WP_104815357.1|1757196_1758099_+|septum-formation-family-protein	unknown	unknown	gnl|CDD|379393

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_158702082.1|1764643_1766425_+|PucR-family-transcriptional-regulator	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	1.65732e-20
NZ_CP025394.1|WP_104815373.1|1781145_1781691_+|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.31853e-11
NZ_CP025394.1|WP_104815368.1|1770666_1771389_-|HD-domain-containing-protein	gnl|CDD|213552	TIGR00691, PppGpp_synthetase., (p)ppGpp synthetase, RelA/SpoT family. The functions of E. coli RelA and SpoT differ somewhat. RelA (EC 2.7.6.5) produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT (EC 3.1.7.2) degrades ppGpp, but may also act as a secondary ppGpp synthetase. The two proteins are strongly similar. In many species, a single homolog to SpoT and RelA appears reponsible for both ppGpp synthesis and ppGpp degradation. (p)ppGpp is a regulatory metabolite of the stringent response, but appears also to be involved in antibiotic biosynthesis in some species. [Cellular processes, Adaptations to atypical conditions].	1.58534e-18
NZ_CP025394.1|WP_158702081.1|1763872_1764328_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|376300	pfam00174, Oxidored_molyb, Oxidoreductase molybdopterin binding domain. This domain is found in a variety of oxidoreductases. This domain binds to a molybdopterin cofactor. Xanthine dehydrogenases, that also bind molybdopterin, have essentially no similarity.	8.61965e-08
NZ_CP025394.1|WP_104815363.1|1766485_1766962_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.96583e-16
NZ_CP025394.1|WP_104815372.1|1780339_1781026_+|Type-1-glutamine-amidotransferase-like-domain-containing-protein	gnl|CDD|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	3.11541e-32
NZ_CP025394.1|WP_104815355.1|1754796_1755417_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|172294	PRK13756, PRK13756, TetR family transcriptional regulator.	2.31609e-15
NZ_CP025394.1|WP_104815359.1|1760415_1761828_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	8.56256e-112
NZ_CP025394.1|WP_158702083.1|1783172_1784762_+|multicopper-oxidase-domain-containing-protein	gnl|CDD|259922	cd13853, CuRO_1_Tth-MCO_like, The first cupredoxin domain of the bacterial laccases similar to Tth-MCO from Thermus Thermophilus. The subfamily of bacterial laccases includes Tth-MCO and similar proteins. Tth-MCO is a hyperthermophilic multicopper oxidase (MCO) from thermus thermophilus HB27. Laccase is a blue multi-copper enzyme that catalyzes the oxidation of a variety aromatic - notably phenolic and inorganic substances coupled to the reduction of molecular oxygen to water. It has been implicated in a wide spectrum of biological activities and, in particular, plays a key role in morphogenesis, development and lignin metabolism in fungi and plants. Although MCOs have diverse functions, majority of them have three cupredoxin domain repeats that include one mononuclear and one trinuclear copper center. The copper ions are bound in several sites: Type 1, Type 2, and/or Type 3. The ensemble of types 2 and 3 copper is called a trinuclear cluster. MCOs oxidize their substrate by accepting electrons at a mononuclear copper center and transferring them to the active site trinuclear copper center. The cupredoxin domain 1 of 3-domain MCOs contains part the trinuclear copper binding site, which is located at the interface of domains 1 and 3.	3.38597e-57
NZ_CP025394.1|WP_104815360.1|1761973_1763062_+|exo-alpha-sialidase	gnl|CDD|374209	pfam15902, Sortilin-Vps10, Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1.	1.41845e-08
NZ_CP025394.1|WP_104815374.1|1781763_1783074_-|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.03918e-29
NZ_CP025394.1|WP_104815361.1|1763351_1763768_+|TOBE-domain-containing-protein	gnl|CDD|182640	PRK10676, PRK10676, DNA-binding transcriptional regulator ModE; Provisional.	6.68014e-16
NZ_CP025394.1|WP_104815369.1|1771514_1772276_-|pirin-family-protein	gnl|CDD|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	2.41841e-65
NZ_CP025394.1|WP_104815358.1|1758265_1760266_+|S8/S53-family-peptidase	gnl|CDD|173788	cd04056, Peptidases_S53, Peptidase domain in the S53 family. Members of the peptidases S53 (sedolisin) family include endopeptidases and exopeptidases sedolisin, kumamolysin, and (PSCP) Pepstatin-insensitive Carboxyl Proteinase. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of Asn in subtilisin. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values. Characterized sedolisins include Kumamolisin, an extracellular calcium-dependent thermostable endopeptidase from Bacillus. The enzyme is synthesized with a 188 amino acid N-terminal preprotein region which is cleaved after the extraction into the extracellular space with low pH. One kumamolysin paralog, kumamolisin-As, is believed to be a collagenase. TPP1 is a serine protease that functions as a tripeptidyl exopeptidase as well as an endopeptidase. Less is known about PSCP from Pseudomonas which is thought to be an aspartic proteinase.	1.96831e-66
NZ_CP025394.1|WP_104815370.1|1772354_1775786_-|error-prone-DNA-polymerase	gnl|CDD|235553	PRK05672, dnaE2, error-prone DNA polymerase; Validated.	0
NZ_CP025394.1|WP_104815356.1|1755582_1757094_+|amino-acid-permease	gnl|CDD|132469	TIGR03428, ureacarb_perm, permease, urea carboxylase system. A number of bacteria obtain nitrogen by biotin- and ATP-dependent urea degradation system distinct from urease. The two characterized proteins of this system are the enzymes urea carboxylase and allophanate hydrolase, but other, uncharacterized proteins co-occur as genes encoded nearby in multiple organisms. This family includes predicted permeases of the amino acid permease family, likely to transport either urea or a compound from which urea is derived. It is found so far only Actinobacteria, whereas a number of other species with the urea carboxylase have an adjacent ABC transporter operon.	2.22981e-52
NZ_CP025394.1|WP_104815366.1|1769251_1770028_+|TIGR03084-family-protein	gnl|CDD|274423	TIGR03084, conserved_hypothetical_protein, TIGR03084 family protein. This family, like pfam07398, belongs to the larger set of probable enzymes modeled by TIGRFAMs family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized. [Hypothetical proteins, Conserved].	1.13086e-106
NZ_CP025394.1|WP_104815365.1|1767598_1769134_+|AMP-binding-protein	gnl|CDD|341283	cd12118, ttLC_FACS_AEE21_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles and Arabidopsis. This family includes fatty acyl-CoA synthetases that can activate medium to long-chain fatty acids. These enzymes catalyze the ATP-dependent acylation of fatty acids in a two-step reaction. The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. Fatty acyl-CoA synthetases are responsible for fatty acid degradation as well as physiological regulation of cellular functions via the production of fatty acyl-CoA esters. The fatty acyl-CoA synthetase from Thermus thermophiles in this family has been shown to catalyze the long-chain fatty acid, myristoyl acid. Also included in this family are acyl activating enzymes from Arabidopsis, which contains a large number of proteins from this family with up to 63 different genes, many of which are uncharacterized.	4.39269e-171
NZ_CP025394.1|WP_104815357.1|1757196_1758099_+|septum-formation-family-protein	gnl|CDD|379393	pfam13845, Septum_form, Septum formation. This domain is found in a protein which is predicted to play a role in septum formation during cell division.	0.000889904

Protein sequences

>NZ_CP025394.1|WP_104815363.1|1766485_1766962_-|MarR-family-transcriptional-regulator
MDGPKDAPRWLDEDEMAAWRGFVAASNLINRRLEQQLKEHAGLSHTQYEVLVHLSAAPDGSLRMTDLADRLVTSKSGLTYQITQLEKAGLVRRRSCASDVRGVFAELTAEGLAALEAAAPGHVATVREVLIDVLSREQLAVLAESLGQVSARLRATGG
>NZ_CP025394.1|WP_158702082.1|1764643_1766425_+|PucR-family-transcriptional-regulator
MIVGDLLELDGLHIGLAWGTSDLLGRQVTGVTSTDLQDPARYLQPGKLVLSGLVWWQPEESSAALRFATSLRSAGVAALLAGEGTHGRVPDSLVAACRTHAIPLLSVPPGTSFRTVTDRVHLRLWGGLHGGTEEVSPLPEAARRELLALLHEDGPLETVLTTALTHAVTTLGLPDCSVHTGSGRLLATSSPPDAAEATPRTATLGTATGTRGAAHRLDPAPRRGSGGPAERLAIGPTGETPFDGWLLRPHTDPGPAAATVLGALAELLAPLAARARTGAAAQRQSAARLLRLLAEDGPGLAEALASCGLPTDVPLIPVTARIDGPNGAPADPASAVAALAEALHQLGLPFAVGPDAAGGATALVAAPRVTAPLATAHPGPAAGHGKPAASRAVTFSESSRVSGKSTASGNALPSRTGTPADKAAAPAVLTARLRLLWPALQGRLPQRRVLRAGVGPAVAPNGRELRAALVEAGYALAAGGTGGGKAGTAVGSSGELSSLAALLRGLPGEVTRTFHARLLAPLTAHDRENAVSLLGTLDTFLDHDGSWARTAEALHIHVNTVHYRIRRIEELTGRSLSLLEDRVDLRAALLCAP
>NZ_CP025394.1|WP_158702081.1|1763872_1764328_-|molybdopterin-dependent-oxidoreductase
MDTTVTAGAVLLHGRFEEPVELTMAHLRALPEHRAEVSFDCLSAGPQRHVFEGALLWDVLRAARPLVDFKGRKQRLRHLVAVTGADGHLVVVSWAEFDPDFGAQPILLATTMDGRPLDAEGPQLVVPTDVCGARYVSGITAVRLAEAAACA
>NZ_CP025394.1|WP_104815361.1|1763351_1763768_+|TOBE-domain-containing-protein
MAMSIRNQLPGTVTTVTTGEVMATVKVWLTGGLELTAAVTVDAVKELGLHAGSAVHALVKSTEVALATGPVPGLSIRNQLPGTVTEVTTGGAMAGVKVTVDAGELTAAITAEAADELGLAAGTPVVALIKSTEVSLSA
>NZ_CP025394.1|WP_104815360.1|1761973_1763062_+|exo-alpha-sialidase
MSEVLLAVGTQKGLFLARSTDREKWELTGPHFPMNAIYSVAVDRRGERPRLLVGADSSHWGPSVWLSDDLGETWEEPTTPAVRFPEHTGTSLERVWQLHPAGPEAPGVVYAGTQPAALFRSTDGGRHFTLDETLWAHPQRAEWAAGFGGQGLHTILTDPRDASAVTVAVSTGGVYRTTDGGGSWHPVNTGIRAGFLPDEYPEFGQCVHKVAADATDPSRLYLQNHGGVYRSDDDGAHWQDIGADLPATFGFGLATHPRRGGTAYLFPLDADYARLPVERRCRIFRTQDAGATWHPLSTGLPAEDHYGVVLRDALCTDDADPAGVYFGNRNGEVYGSRDDGDSWQLITSHLPDVLCVRAAELG
>NZ_CP025394.1|WP_104815359.1|1760415_1761828_+|NAD(P)/FAD-dependent-oxidoreductase
MESQTYDVVVLGAGPTGENLADRTKAAGLSTVVVESQLVGGECSYWACMPSKALLRPAAALAHARALPGAKQAAAGELDVAAVLARRDEFTSHWHDEGQVSWLDSVGIDLVRGHGRLAGEKAVLVDGERLLTARHAVAVCTGSRAALPHTPGLAEAHPWTSRDATSAAEVPPRLAVVGGGVVAVEMATAWNALGSRVTLLVRGSALLDRMEPFAGELVAAGLAEAGVELRFGVSVEALHRDGGPVTLTLSDGGTLEADQVLYATGRAPRTDDIGLETVGLTPGSWLEVDESCAVTGVAGGWLYAAGDVNHRALLTHQGKYQARIAGAAIGARAAGTPLDTARWGRHAASADPAGPPQVVFTEPEATAVGLSLAEAERAGLRVRAVDHDLGQVAGASLYGDHYRGRARLVVDLDREVLVGATFVGPGVAELLHSATVAVVGEVPIARLWHAVPAYPTVSEVWLRLLETLRG
>NZ_CP025394.1|WP_104815358.1|1758265_1760266_+|S8/S53-family-peptidase
MTPRRRLLAAAASPLLALALAAPVGAAPSPQHRVVVPGTHPAWAQASADLGPVGANAPVTVRIYLAGQDEAELTAFAQAVSDPHSTHYRHFLTPQQVRERFGPSPEQTASVHRWLSSAGLTISRQTDHYLVAEGTAEQAQRAFAVQLHSFRREAHTYQAPVGEASVPAEVASAVLAVHGLNTAPHQVHHGSGANRPAAARSVPQDTLPGPAPAFVNSGPFSSYYGEKPATGTPEAYGQVQPYVIQGYDGARLRSAYGASATGLTGQGVTVAIVDAYDSPTLDQDTATYAAAHGDAPYAPGQLMHDDPAEWTHTQAPTDADPTGCGAQGWYGEQTLDVEAVHAVAPEAGIQYVGAASCQDPDMIDALRRVVDGHLADIVSNSWGEAENASDPALDPVYQQIFHCGAAEGIGFYFSSGDDGDDLASTGTKQTDMPASLDSVTAVGGTALGLDQDGAYSFETGWGTLKAPLSSDGTSWTNFPGAFTSGAGGGTSGRVKQPSYQRKVVPRSLSGANGGRNRVVPDIAAVADPNTGFLVGQTQTFPNGEARYSEYRIGGTSLAAPVISGLQALAQQASGKPIGFANPAIYQRYGSSAFHDVTDQPFGPDHDLAEVRVDFVNGVDASQGTVTSLRSLGKDSSLHAVEGYDDVTGVGTPTADYLTSYAEAPKH
>NZ_CP025394.1|WP_104815357.1|1757196_1758099_+|septum-formation-family-protein
MRSGAAAAVGAGLVAAALTGCTQHTAGPARPSPTATASPSASATPARVLAAGLVAGDCFTTRGKGYLDVQRVDCAQPHDGEVFGRARFETTEFPSADLPPEQELHSTAAVECADAFGQFAVDSWALPDTVRLVYAYPDRPGWHEWSSRQAACVLTDTNGPRTGSLREDPSRFTQDQLTFLETENGLDGVLRQTAQDKDLAQNPTWGRLLRQAAASTATSLEEWPWPAAAAPAVKALSARLREAEGHLTAAANMRSPEARKQETDAALDQLTHAPVGPVRAALGLTTEPRSTDVPAALGDT
>NZ_CP025394.1|WP_104815356.1|1755582_1757094_+|amino-acid-permease
MAHTPPETRPQGDADRLAALGYRQELRRSLGILGNISMGFAVVSPVVGLYTVAQLGLGVFGGAWVWALPVCLLGQLLVVCVYSELASQWPLAGGAYQWTRRLTGPTFAWLSGWMWQFAVMFANTTVAYLAAPWFFALFGVTPTPAELVLTAAAFLIGCTLVNAYGINLLRWFVSLGIAAEAVASVLVTLALLLFFRAHGFGLLLDTLGAPATTGTGGFSAFLAVVAVGGWAFIGFDACVSTAEETKDAARQVPRAMRWALLSVGTAVILSAVSITLAHPDPSAVSQGTDLDPVTTAVTTGLGGWADKPFVVVVLISFAACLMASQGGAARGLYSLARDGVFPWSAQVRRVNRHQAPIGGLVAATLVSCAALPLGLKTAAMGSLITFGTAATFLPFFLLSLAALIARLRGSWQPAGLVSFGRWGTVLNLLATLWTGLEVVNICWPRTILAPPGAPWYQVWAALLGVGLVTLAGCGYLLARRPQRLMRGPAAERPDTEGLAPAVI
>NZ_CP025394.1|WP_104815355.1|1754796_1755417_-|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MGRPSRAVLSRQNIARAALDLVDEQGSDGLTMRAVAERLGVKAASLYNHVSGREDILDGLAELVNAEIDLGALAADSPLPWREGLAVYARGYRAAFLRHPHTIALLARRRVGAERQLLGYETLLAALARAGLTPADAAEAAAALDYLVLGSALETFTAGFTLPPADYAPAYPALATALEASTARPGTLDDRGFDLALRLLLAGLGR
>NZ_CP025394.1|WP_104815365.1|1767598_1769134_+|AMP-binding-protein
MQTPLTLMDFLDRAELVYGDRIGVIDEPDQPAASWGELTYRQLAARARAQAAGLDRLGVGPGERVAIVSHNSARLLTALYGVSGHGRVLVPVNFRLKAEEVAYIVEQSGATVLLIDPELADALAGVPCRHRFVLGAESDAELYDYENEPVRYEIAESDTATINYTSGTTARPKGVQLTHRNLWLNAVLMGLHFGANDRDVYLHTLPMFHANGWGMPFSLTGLGAQHVVLRKVDGAEILRRVERHGVTFLCGAPAVVASILDAAADWDGPVPGRDKVRMIVAGAPPPTTLVQRMEAELGWEFMQIYGLTETSPIATVNRTRAEWDDLPAAERAEHLVRAGFPALGSQVKVDGQGEVLIRSNTVLDGYWERPDETSAALKDGWFHTGDGGAFDQDGALGISDRKKDVIITGGENVSSIEVEDCLYSHPAVAEVAVIGVPDAKWGETIKALVVLKEGQQADEAGLIAHCKARLAGYKAPTSVEFRDVLARTTTGKLQKFRLREPYWTGHTRAVN
>NZ_CP025394.1|WP_104815366.1|1769251_1770028_+|TIGR03084-family-protein
MTDLTALLDDLRAESAELDGLVAGLDAAGLTTATPAPGWTIAHQLAHLAWTDRWALLAARDAEGFAKATAAAFAAGGDPVEAGAAEGVGEAPAELLGRWRAGRADLAEALAEAAAADRKLPWFGPPMKAGTMATARLMETWAHGQDVADALGATRAPAARIRHVAHLGVRTMGFAFTLHGQPAPTDPVRVELTGPDGELWTWGPEEATDRVSGPALDFCLLVTQRRSRAELALQAEGPTATAWLPIAQAFAGPPGKGR
>NZ_CP025394.1|WP_104815368.1|1770666_1771389_-|HD-domain-containing-protein
MTQLSVAEVDALAEAAHRGQADKTGAPYIGHVRAVAAGLAPLGAELEMAGLLHDVIEDTEWTAERLLAAGVPAAVVETVEVVTKRPGVPYEEMIRAVAAHPAARLVKIADNAHNSLAHRAARLPFEQRERLAAKYAAARRLLWPAVDRQHLETVLWRVNPALLAELPDSSRESGGSGGGLPTERTAAGVTALPPPGRDHSLRSTPSTGCWRRCRPTAAGGWCPCPAGSGCSTRRCRRPGS
>NZ_CP025394.1|WP_104815369.1|1771514_1772276_-|pirin-family-protein
MASVLDIRRADDRFHTRTSWLDSRHSFSFSRHWDPANTHFGLLLVSNDDVVAPGTGFDTHPHRDMEIITWVLEGGLVHQDSEGHNGVIYPGLAQRMSAGAGILHSEKNDSWTLTGEPEHEQPVRFIQMWTIPDTAGIQPGYEQLDINEELARGGWVTLASGMPEHASQRAIGIRQKHAALHVARVRAGETLRLPDAPFAHLFVAKGSVELEGAGPLGTGDAGRITGSEGQRLTAGPDGAEVLAWEMTAAVMVG
>NZ_CP025394.1|WP_104815370.1|1772354_1775786_-|error-prone-DNA-polymerase
MGFTNHPSLSWQELNRRLSGAPAAPLPEPETPDPIAPSRSNGPSRPNGPSGPYRQDPAAAWAELHVHSAFSFLDGTSDPEALATEAARLGVETLGLTDHDGLYGVVRLAKAAKELGLSTVAGAELTLGPEEHLLVLARGPEGYRRLSAAISAAQLAGGVKGRPVYEFAELAAAHGGHWAVLTGCRKGRVPAALSTTGGERALHGGKFLHDGQSLLSGQLHPDGQLRPDGRSPLGGRPLPDGRPLPGEPAAPNARAAAGRARAERELRVLAEAFGSENVYVELIDRRLPGDDLRNDRLAALAARVGLTTVASNNVHQAGPAQARLAQGLAALHGRRTLQEAAGWTDAAGAAHLRSGAEMARRLARFPGVQRATVELGRDCAFEFTSLAPALPGFPVSEGESEIGHLRALVVEGGPRRFGAENAAARKQLAVELDVIEQLGLAGYFLIVHDIVEYCRREDIWCQGRGSAANSAVCYALGITAVDPIRYRLLFERFLSVARDGPPDIDLDIEHRRREEVIQYLYRRYGREHAAQVANVITYRPRLALRDAARVLGYPRAQVDAFSRQSDFRAQPTADALIPADVLGLAQELHGLPRHLGIHSGGMVLTERPIGEICPTEWARMPGRSVLQWDKESVAGAELVKIDLLGLGMLSALHDTCDLIAEHHGLRYDLASIPKEAAEVYEMLGRADTVGVFQVESRAQMATLPRLKPTRFYDLVVEVALIRPGPIQGGSVHPYLRRRAGLEPSTCPHPSMENALGKTLGVPLFQEQMMQLAIDCAGFSPAEADRLRQAMGAKRSHQRVAELRERLLAGMAARGIPAETAEDVYGKIEAFSNYGFPESHAISFAYLVYASAWLKHHYPAAFTCALLANQPMGFYSPLSLTADARRHGVRVRGVDVNSSAPAPSLEPDEGAPAPAPMGRSPHPQPAVRLGLTAVRGLGAAAAEAVAAGRPYADLEDFARRTGLATPVLEALATAGAFGCFGLSRRQALWAAGAYAGSAGVLPGTAPGTEAPGLPPMTPVEETIADLWSTGTSATSHPLQHLRASLAHGGALSAAELARTPHGTPVVVGGLVTHRQRPPTAGGVLFLSLEDETGLINVVCNRAVWEPQRRTALDRAGLLVHGHVERREGAVNLVASRLTALRIGV
>NZ_CP025394.1|WP_104815371.1|1778519_1779188_-|hypothetical-protein
MLPVLPALAALLPEGGLRRGAAVSVAGDTGLLLALAAGASGLGEAGGAGVDVSATAGGEWVAAVGLPELGLGAAAGYGLDLRRLLLVDDPGGQWPEVVATLAPAVGVILLRPDGPVSPQLATRLTAVLRRGGCALLVAGPWPGAVLQLRLAAARWYGLGAGHGQLQGRQVEITAQGRGGAARPRAARLWLPDEYGAARPFEPSDEFAPGFERAAPSGRLAAV
>NZ_CP025394.1|WP_104815372.1|1780339_1781026_+|Type-1-glutamine-amidotransferase-like-domain-containing-protein
MKLLLTDSGVNNPSIQAALVDLLGKPIAEADALCIPTAGYASPNGSPFGPWRFISGNSHCPMTGLGWKSVGVLELTALPSIDRELWTGWVRAADVLLVNGGDALYLAHWMRESGLADLFPSLTETVYVGFSAGSMVLTPRIGAEFVGWQQPGGDDRTLGLVDFSIFPHLDSPACPENTTADAERWATTMTGPAYAIDPETAIKVVDGRVEIVSEGHWKLFDQPLDATV
>NZ_CP025394.1|WP_104815373.1|1781145_1781691_+|GNAT-family-N-acetyltransferase
MSHLIRAVTAEDWPRVKELRLAALLDPVADIAFLETYENAAAQPDEFWQQRAAGARGEMIARQFVAERPDGGWDGSVSVLIERAGRPDVLGRPNEFDQAHLVGVFVRPEQRGTGLARELFDAAVAFARELEEPAVERIRLFVHEKNTHAEAFYRKIGFARSGNTFPVPGDESSIEHELVLG
>NZ_CP025394.1|WP_104815374.1|1781763_1783074_-|MFS-transporter
MTSGGTATGTEQRISETAAAGPQRALITAHFISRVGNGLFNTAAILYFTFVVGLHPAQVGAGLTIAGLAGLAAGLPAGNLADRYGPRTVWLTTLTLQAVTMAAFVFIDGWLAFTLVATLDRLAATAAGAAGGALVARVGGERPAAFRARLRTFVNLGVVLGTLGAGFAIQLGTRAAYTGLILANAASFALAALVVLLGVPGYRPLPKPAGHRRWSVLADRPYVSFVALYSAMGLQYQTAALLLPLWLTAHTDAPRWTVALVNATSSGVCVLLQRRLGAKVETPTQGGRAFRRAGLLFLLSCPLMALTADVPAWVAPALAFLAVCVHSIGEVWESSAAFALGYGLAPDHAQGQYHGLFGIGFDTGQALAPLVLTGAVLALGQPGWLLLGVLFAALGAAGPPVAAWAERTRRPLAEPTGPSPSPSPIPIPAAAAETVG
>NZ_CP025394.1|WP_158702083.1|1783172_1784762_+|multicopper-oxidase-domain-containing-protein
MGESVGISRRSVLKAAAAAGLGVAVDQVAAGRAAAAASPAAAAFPQSAEAGRRVVAQTLDVRYAEVEVPGYGTVTTRAYNGTVPGPTLRVRGGDLLRLTQVNGLPPNPPHEGGPHTPHHPNSFNLHTHGMHVSPAGEADNVLREFAPRTAEEVAAGAPEPRYTTVIEVPADHPAGTYWYHPHLHGATAEQLAGGLAGVIVVEGDVDEVPEIRAADELVLCINELKLKDGKVPPFSSGGWMSGVPSVFTVNGAVNPTLGLRPGEVQRWRLVAATAFTALNIELTSSASNLTLHQIAQDGVTFAAPVARARLELAMGNRADVLVLGGQPGRYELRADGVAEPLLTVEVAGEAVEPPMRLPELLPPGRPLIEEQELTDPAAEREVLFHVDPNVFPGDFPNAYRVLGSHPTPAVDPDGDLGHDPAYGLFDPCYTNHTLRLGTVERWTVRTGETSPFLNHPFHLHTNQFLVTHRNGERLDPPVWHDTVGLAGGQPGESVTFLVRYQDFTGRTIAHCHHLHHEDLGMMQTVDYVR

Crispr_ID: NZ_CP025394_5

• CRISPR_ID: NZ_CP025394_5
• CRISPR_location: 1935371-1935456
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_5

Consensus_repeat	Method
GCCGAGTCGAACCACTCGTCCAC	CRISPRCasFinder

spacers of NZ_CP025394_5

>5.1|1935394|40|NZ_CP025394|CRISPRCasFinder
CGTGGGCTCCGGCCGCCGCTGGGCGCCGATCATGCCTGCG

CRISPR arrays and Neighbor proteins around NZ_CP025394_5

CRISPR arrays

The CRISPR arrays of NZ_CP025394_5

>merge|NZ_CP025394|5|1935371-1935456|CRISPRCasFinder
GCCGAGTCGAACCACTCGTCCACCGTGGGCTCCGGCCGCCGCTGGGCGCCGATCATGCCTGCGGCCGAGTCGAACCAGTCGTCCAC

>NZ_CP025394|5|5|1935371-1935456|CRISPRCasFinder
GCCGAGTCGAACCACTCGTCCAC	CGTGGGCTCCGGCCGCCGCTGGGCGCCGATCATGCCTGCG
GCCGAGTCGAACCAGTCGTCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104814759.1|1938002_1939136_+|IS630-family-transposase	unknown	unknown	gnl|CDD|379267
NZ_CP025394.1|WP_104815492.1|1941783_1943376_-|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl|CDD|225080
NZ_CP025394.1|WP_104815483.1|1931858_1932764_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP025394.1|WP_104815488.1|1937240_1937921_+|DUF305-domain-containing-protein	unknown	unknown	gnl|CDD|367619
NZ_CP025394.1|WP_104815491.1|1941253_1941787_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl|CDD|223427
NZ_CP025394.1|WP_104815487.1|1936563_1937244_+|DUF3105-domain-containing-protein	unknown	unknown	gnl|CDD|378632
NZ_CP025394.1|WP_104815494.1|1943957_1944398_+|ASCH-domain-containing-protein	unknown	unknown	gnl|CDD|119345
NZ_CP025394.1|WP_104815482.1|1931043_1931862_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP025394.1|WP_104815484.1|1932989_1933604_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|132427
NZ_CP025394.1|WP_104815477.1|1925624_1926335_+|urease-subunit-gamma	unknown	unknown	gnl|CDD|183886
NZ_CP025394.1|WP_104815493.1|1943403_1943883_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP025394.1|WP_104815481.1|1929605_1931021_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270451
NZ_CP025394.1|WP_104815489.1|1939060_1940572_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP025394.1|WP_158702091.1|1924363_1925338_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176189
NZ_CP025394.1|WP_104815479.1|1928112_1929156_+|agmatine-deiminase-family-protein	unknown	unknown	gnl|CDD|377332
NZ_CP025394.1|WP_104815480.1|1929232_1929502_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104815478.1|1926366_1928085_+|urease-subunit-alpha	unknown	unknown	gnl|CDD|237305
NZ_CP025394.1|WP_104815475.1|1923787_1924246_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP025394.1|WP_104815486.1|1935906_1936452_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104815490.1|1940707_1941238_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224759

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104814759.1|1938002_1939136_+|IS630-family-transposase	gnl|CDD|379267	pfam13565, HTH_32, Homeodomain-like domain.	3.92471e-09
NZ_CP025394.1|WP_104815492.1|1941783_1943376_-|DNA-3-methyladenine-glycosylase-2-family-protein	gnl|CDD|225080	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism].	1.70698e-59
NZ_CP025394.1|WP_104815488.1|1937240_1937921_+|DUF305-domain-containing-protein	gnl|CDD|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	2.08313e-52
NZ_CP025394.1|WP_104815493.1|1943403_1943883_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.17669e-12
NZ_CP025394.1|WP_104815491.1|1941253_1941787_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl|CDD|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	6.70713e-50
NZ_CP025394.1|WP_104815477.1|1925624_1926335_+|urease-subunit-gamma	gnl|CDD|183886	PRK13192, PRK13192, bifunctional urease subunit gamma/beta; Reviewed.	5.00393e-99
NZ_CP025394.1|WP_104815487.1|1936563_1937244_+|DUF3105-domain-containing-protein	gnl|CDD|378632	pfam11303, DUF3105, Protein of unknown function (DUF3105). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.59613e-59
NZ_CP025394.1|WP_104815483.1|1931858_1932764_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	6.80884e-80
NZ_CP025394.1|WP_104815484.1|1932989_1933604_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|132427	TIGR03384, betaine_BetI, transcriptional repressor BetI. BetI is a DNA-binding transcriptional repressor of the bet (betaine) regulon. In sequence, it is related to TetR (pfam00440). Choline, through BetI, induces the expression of the betaine biosynthesis genes betA and betB by derepression. The choline porter gene betT is also part of this regulon in Escherichia coli. Note that a different transcriptional regulator, ArcA, controls the expression of bet regulon genes in response to oxygen, as BetA is an oxygen-dependent enzyme. [Regulatory functions, DNA interactions].	5.88334e-11
NZ_CP025394.1|WP_104815475.1|1923787_1924246_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.4132e-13
NZ_CP025394.1|WP_104815481.1|1929605_1931021_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.49401e-109
NZ_CP025394.1|WP_104815489.1|1939060_1940572_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.57566e-36
NZ_CP025394.1|WP_158702091.1|1924363_1925338_-|zinc-binding-dehydrogenase	gnl|CDD|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.13791e-62
NZ_CP025394.1|WP_104815479.1|1928112_1929156_+|agmatine-deiminase-family-protein	gnl|CDD|377332	pfam04371, PAD_porph, Porphyromonas-type peptidyl-arginine deiminase. Peptidyl-arginine deiminase (PAD) enzymes catalyze the deimination of the guanidino group from carboxy-terminal arginine residues of various peptides to produce ammonia. PAD from Porphyromonas gingivalis (PPAD) appears to be evolutionarily unrelated to mammalian PAD (pfam03068), which is a metalloenzyme. PPAD is thought to belong to the same superfamily as aminotransferase and arginine deiminase, and to form an alpha/beta propeller structure. This family has previously been named PPADH (Porphyromonas peptidyl-arginine deiminase homologs). The predicted catalytic residues in PPAD are Asp130, Asp187, His236, Asp238 and Cys351. These are absolutely conserved with the exception of Asp187 which is absent in two family members. PPAD is also able to catalyze the deimination of free L-arginine, but has primarily peptidyl-arginine specificity. It may have a FMN cofactor.	5.80314e-152
NZ_CP025394.1|WP_104815478.1|1926366_1928085_+|urease-subunit-alpha	gnl|CDD|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
NZ_CP025394.1|WP_104815494.1|1943957_1944398_+|ASCH-domain-containing-protein	gnl|CDD|119345	cd06553, ASCH_Ef3133_like, ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation, RNA-processing and the regulation of prokaryotic translation.	2.74942e-34
NZ_CP025394.1|WP_104815482.1|1931043_1931862_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.02981e-80
NZ_CP025394.1|WP_104815490.1|1940707_1941238_+|MarR-family-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	6.65759e-15

Protein sequences

>NZ_CP025394.1|WP_104815484.1|1932989_1933604_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MAEPRTRRAARPREEVYATARAAIAEHGLAKLTMAALGKQLQMSAGHLLYYFGSKDQLLLETLRWSEEQLGERRRAALSRAAGDGWRQLAAYADLYLPEGPGDPRWILWLEVWGRSPASAEIRQGQLDIEAPWHADLVAVLEAGYASGEFTPAAPGASPDDRAVQLRALLDGFAVPVAIGLPAATREQAATQVAAVSRGLLGRG
>NZ_CP025394.1|WP_104815483.1|1931858_1932764_-|sugar-ABC-transporter-permease
MPTAPPTRPRRWGERSLAWAFLLPSLAVFALFLGWPLVRTFYLSTHANDLFGAPSRYVGFKHYTDLLGSAEFHRTLLTTALFVLLTVVPGVLGALAVVLLLESRIRGVRAFRSAFALPFAFSVASASVVFSVFYNPAGGVLNGLLGQLGAGPVGWLTDSRYALLSVALTSVWMSLGYNILVLSAGLGSISPEITEAARLDGAGGWRLARSVTVPLLGPHLFFLVVVSTITALQSFGQIHILTRGGPDGATRTLVYSVYERAFAYGSSDFGTASAQAVVLLVVVLACAAAQFGVLDRKVHYA
>NZ_CP025394.1|WP_104815482.1|1931043_1931862_-|carbohydrate-ABC-transporter-permease
MSRALSRILTYAVLVVAVLAVLFPVYYVIAGSFMTPGELIGYPPSLLPHQLTGHNFAAAFHAVPLGRQYLNSAVTAGIITVAQLLTSILAAYAFVFLPLRRRGLVFGVFLATLMVPWEAVIIPNYLTLSGWGLADTYAGLVLPFLASGFGTFMLRQSFRQFPAELRDAARIDGAGHWRFLWRVLVPLNKPSLAAIAVYVFLSAWNQYFWPLIITRTAQMQTIQIGLTSLRDAEVADPGLTLAGVVLSLLPTLLLVVFGQRFIVRGLTAGAVR
>NZ_CP025394.1|WP_104815481.1|1929605_1931021_-|ABC-transporter-substrate-binding-protein
MRRRTVVTSRAWALRLAATVAAAGLALTACSSSGSSDGSSGDAAAPAASVLDQAKGVTTVTFWHSMTGQNATVLNSLVSSFNAAHQGRIEVKALFQGTYDDVVTKYKASVQQKATPSLVQVYDVGTRFMIDSRQTVPVQAFVDRDKYSLDDLEPNIRNYYTVGGKLASMPFNSSVPLLYLNADAFKAAGLDPAQPPRTLAEIADLAKKLTVKDASGQTTRYGFGAAIYGWFVEELLAESGSLYCDQGNGRDGKAAKVGYDSAQGAQVLQTWADLVKGGYAVNTGRTTADAQAAFKAGRVAIHLESTGVLRGYNESAKFTVATAPFPKLAAGDQGGPVIGGASLWIDGPGHSDAEKRASWEFAKYLDEPAQQAVWHTGTGYFPVNRKALDDPKDQAWVAKYPQFKTAIDVLHSTKPTPATAGCLLGVMPQARKGVETALEQVISGSKAADQALADAAKELQPAIDGYNSSVG
>NZ_CP025394.1|WP_104815480.1|1929232_1929502_-|hypothetical-protein
MTTEDETRDAVHRILGDVHLELTEFPGGNISLTVSDDHHSATVDGHPVSGYGWTVDPGEDDGFTGHDQISPTLEDALEAVRAEFGLDED
>NZ_CP025394.1|WP_104815479.1|1928112_1929156_+|agmatine-deiminase-family-protein
MTETPAALGYRMPAEWHPHERTWMAFPTDNPTFDSPEHLHSSRLAWARVADTIVRYEPVTLIVNTGETETARGYVSPEVEIVERPLDDAWMRDIGPSFLLGPDGELAATDWIFNGWGAQGWARWDKDQHIAEEIAGLTGVRRFASRLINEGGGIHVDGEGTVLVTDTVQLGEGRNSDWTREEVEAELNAFLGTTKVIWVPRGLTRDYDEFGTRGHIDIVASFVRPGVVVAHTQPDPAHPDHEVCQEIVALLRAATDAAGRTLEVIELPAPTVLLDEDGEPVDYSYINHYVANDAVILCAFDDPRDTEAQAILAKAYPTRTVELVDAREIFANGGGIHCITQQQPKAG
>NZ_CP025394.1|WP_104815478.1|1926366_1928085_+|urease-subunit-alpha
MSAITPHDYISVHGPRAGDRIRLGDSGLIVRVESDSQAPGDEFLAGFGKTARDGLHLKAAAVRDTCDVVISNVLVIDAIQGIRKTSIGLIDGRIAAIGRAGNPDTLDGVEVVVGTGTTIVSGEGMIATAGAIDTHVHLLSPRIMEASLASGVTTIIGQEFGPVWGVGVNSPWALRHAFNAFDAWPVNIGFLGRGSSSDAAPLVEALVEGGASGFKVHEDMGAHTRALDTALRVAEEHDVQVALHTDGLNECLSVEDTLAVLEGRTIHAFHVEGCGGGHVPNVLKMAGVENVIGSSTNPTLPFGRDALGEHFGMIVSAHDLKVDLPGDAAMARDRIRAGTMGAEDVLHDLGVIGITSSDAQGMGRAGETVRRTFAMAGKMKAELGPLDGGFGTTESGDDNERVLRYIAKLTINPAIAHGLAHEVGSIEVGKLADIVLWRPDHFGAKPQLVLKAGFPAYGVVGDPNASTDRCEPLVLGPQFGAHGATAADLSVAFVAQAAADGSYLDRAADQLPTRRRRVGVRGTRGIGPRDMVRNARIGHVQVEADTGLVSLDGEPLRSEPADSVSLSRLYFL
>NZ_CP025394.1|WP_104815477.1|1925624_1926335_+|urease-subunit-gamma
MRLTPTERDRLLIFTAAELARARRARGVRLNVPEATALIADTVCEAARDGRRLAEAIEAGRSVLTAAEVLPGVPDIVTTVQVEAVFEDGTRLAVINDPFRGAGSLGEQAPGGALIGSGAGYDPVEETVVLPVHNTSAVPISVTSHFHFFEANPRLAFDRSAAYGTHLAVPAGSSVRFDPGATVEVGLVPIGGERVAIGFAGLVDGPLDAPGAREAALAKARATGYLTSFDDAEIES
>NZ_CP025394.1|WP_158702091.1|1924363_1925338_-|zinc-binding-dehydrogenase
MRAIRYTRTGGPEVLEVADGLPLPEPGPGEVAIEVSHAGVHFADVMFRRGQFPLPLPAVPGLEVAGTVAALGEGVTGLRVGEPVVAVPTGFGGNAERVIAGAVATVPLAGELAGLDPRLAAATACNAVTAVGTLRSAARVGEGDRVLVLGAAGALGALLGPLARHYGAALVVGAAGTPERAAAAGGYDQVLSYDEIANRVGELTQGQGFDVVIDSVGGEPRGQVRGWLAVFGRHVVIGNAADRDLTLAANEVWYESFALTGYNMGGLLGRRPELFRAHLEEGLRLVADGTLKTSVEEVDWAGVAEAHRRLEGRTAETKYVLRVR
>NZ_CP025394.1|WP_104815475.1|1923787_1924246_-|MarR-family-transcriptional-regulator
MTTDPAELLAGPQGVPHRLGLQIKQAEQAMMAAKAEALRALDLTVPQYAVLLQLTERAGMSGAQLARGAAVTPQTMAGLLANLEAKGLVEREPSELHGKVLVTRLSPAGRVLVAAADARAVEVESVLWTAFEEGERELFRGFLQRATAALRK
>NZ_CP025394.1|WP_104815486.1|1935906_1936452_+|hypothetical-protein
MTVPGAKTPQLGRALHAARPAARLWALVLVGLLALLPCAGRAQAVTAGPAAEQAAQTAQAAPVTRTAQAAPTTQVAKSAPRHQLKAGHLASLLADAGLLTGHGVPQTLCVAGDQPPHPGDGCSNHPFCGSESQLPNAPPQADAPVPALLVPAAVPACPALGASKPGAVPAPDLHELQVHRI
>NZ_CP025394.1|WP_104815487.1|1936563_1937244_+|DUF3105-domain-containing-protein
MGSASKQSNKAAKPGSRQAEQNDRRARIAALRAEEQRRERRNKFLAFGIAGVLIAGMAGTGIYLALDAKDKHDAKVSAAKAPIEGVKTWDKLSRNHVQTPVTYPQTPPVGGDHNPVWLNCMGTVYDKPQQNENAVHSLEHGAVWVTYNAKATPDDIKTLSARVQKTPYSLMSPYPTEPGTITLTAWGTQLIVDKADDPRVAQFFTKYVQGPQTQEPGASCSTGAMG
>NZ_CP025394.1|WP_104815488.1|1937240_1937921_+|DUF305-domain-containing-protein
MTSDHDEPTAEAAPVRSRRRVWWPAALAAAVALGLGVPALVASGSSASGSSVSVPANDSPEAGFARDMATHHQQAIDMSFIVRDRTTNEEVRNLAFDIINTQANQRGMMMGWLDQWGLPQSNGVTPMAWMKMEPYQAHDGSLMPGMATNADLAKLRTLSGKDAEIFYLQLMIRHHTGGVEMAQGYVDLSSNPVEKRLAESMVNGQRSEIDLITQMLAERGAKPLPN
>NZ_CP025394.1|WP_104814759.1|1938002_1939136_+|IS630-family-transposase
MAERVQVREIDDDEGRRLLRIVRRGTGSVVTWRRAQMVLLSAQRMPVAKIAEVTFTSADRVRDVIHNFNADGFDSLYPKYRGGRPRTFTLPERREIKKTAKSKPAEHGLPFSTWSLAKLADFLVAEGVVDDISHEGLRVLLREEGVSFQRVKTWKTSRDPDYAAKKARVEHLYAIADGEVVPEDGEPEVVFCLDEFGPLNLQPHPGKQWAERGGRHKDPDREPRPRRRATYTRPHGVRHLFAAYDLAKDQLYGHVKKTKNRSRFLEFCRYLRSLHPADVRIAIVCDNYSPHLTTKRCQRVGTWAAANNVEIAYTPTNSSWLNRIEAQFTALRYFALDGTDHPSHKAQGSMIRRYIIWRNKHAQDERLRKVVTRANVA
>NZ_CP025394.1|WP_104815489.1|1939060_1940572_-|MFS-transporter
MRSALLTDLLAERPRPRVVARRPYAHWLAVGTVCLGAFLGQLDASIASLTFPALQREFDAGFAAVEWVSLVYLLVLVALLAPVGRLSDLVGRKTVYLGGFGVFALASLGAGSAGSLGLLIACRGVQAVGAAMLQANSVALVARGVPARAMRTALGIQAAAQALGLALGPTLGGLLVAHASWRWVYWVNVPIGLLGILAGWYLLPRTQGCPALEAPAAGHRRFDLLGLVLLAGAGTSLLLGLSAASGLPLPGWAVAALLLLAAALTVALARQEQRADRPIIAPGLVNTPGIRAGLGVALVGYLLLFCPLVLGPVLLTGAGLSVATAGLVITALPTAFAVAATVGGLLLPRSWADAARCQLGAGVAALGIGLLAVLPVGAWEWVPALAVAGYGLGLLLPANNAMVMRAIPGGSSAVGGGMVSMARSLGTALGIALPVLGVHLGGQAAGGRGVLVLLVGVAAGAARLVAQFPAPLVADLVPHQATFALVTTLRRRSSWACLFRQMM
>NZ_CP025394.1|WP_104815490.1|1940707_1941238_+|MarR-family-transcriptional-regulator
MPSQPLPGTPHLPAATPTTPVGDTAVERAQQLTDVITRLRRALRSSIRTDYPWESLPMAQVELLQTLAVAPLRVGELAARQRLAPNTVSGLVGKLLEAGFVDRQPDPGDRRTARIALTPAGHQQLRDWQGAHERRLADALESLTPTNREAVMNALPGLEQLAKALAATTPIPTEER
>NZ_CP025394.1|WP_104815491.1|1941253_1941787_-|methylated-DNA--[protein]-cysteine-S-methyltransferase
MSTTVFTTMASPLGTLLLSGVLAEGASTAALAAVTAPGQKGARAEPAEDWVPDADALAPAVEQLTAYFAGERKEFDLELAPVGTEFRQRIWAALDEIPYGSTLTYSELAAVAGQPPRSVRAVGGAVGANPLLVVRPCHRVLGSNGALTGFAAGVPAKRWLLELEGALPSGEEEGLLF
>NZ_CP025394.1|WP_104815492.1|1941783_1943376_-|DNA-3-methyladenine-glycosylase-2-family-protein
MSDFRQSLGAGWRRLEGVIDDETRYRAVDSRDARFDGVFFTGVRTTGIYCRPSCPAVTPKRVNCTFYPTAAAAQGAGFRACRRCRPDAVPGSPEWNHRADLVGRAMRLIGDGVVDREGVGGLAGRLGYSARQVQRQLTAELGAGPIALARAQRAQTARLLLQTTDLPVTEVAFAAGFASVRQFNETVREVYDRTPSGLRAEGAAGRRLATPAGPLSLRLAYRGALDSDHLIDFLALRAVPGVEEVVPGPRGARTYRRTLALPYGHGIAEVDGLGPRDRADRGWLDCRLHLADLRDLTTAVHRLRALFDLDADPAAVDSVLGASPVLAAAVRARPGLRSPGHVDPHELAVRAVLGQQITVVAARTLAARLTERYGVPLAETSGGLTRLFPTTAVLAEAADEDLAMPEARRRALRGLCAALAEGTVRLDGGVDREEASAELLALPGIGPWTVGYLRMRALADPDVFLPGDVAVRHGLRALGRPGDPKGATAEAAAWAPWRSYAVHRLWAGPVAADPGSGTDFENSAESGEQR
>NZ_CP025394.1|WP_104815493.1|1943403_1943883_-|GNAT-family-N-acetyltransferase
MTIIRVATVERDLASLVRLNGQVHAEHARQRPDLFVVEQPTEELAVLLAARLAEPDATCFVAEAPDGTVVGYAFAKVISREANAIVRAARAVMLDQIGVDPAAARAGVGAALLEAVRELGRSAGCGRLVTQVWDFNEGARAFYQAAGLRPMTTMLDQRL
>NZ_CP025394.1|WP_104815494.1|1943957_1944398_+|ASCH-domain-containing-protein
MTTPEHSSLPKAEFAFPGPLRDQLVAAILDGSKTSTTGLVIDFEVCGDELPTVGSRAAVVDSDEQPVGVIEYTEVRTAPLAEVDLQHAIDEGEGFTTVAAWRADHTSYWEGPEVRGAIGIPDFTVDDTTPLVLMRFRLLTPEEAAS

Crispr_ID: NZ_CP025394_6

• CRISPR_ID: NZ_CP025394_6
• CRISPR_location: 2810742-2810903
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP025394_6

Consensus_repeat	Method
GGTCCGCCCGGGCGGGGTCCGCTCGGG	CRT

spacers of NZ_CP025394_6

>6.1|2810769|18|NZ_CP025394|CRT
TCCGGTCCGCTCGGGTGG
>6.2|2810814|18|NZ_CP025394|CRT
TGGGGGTCGCCTGGGTCC
>6.3|2810859|18|NZ_CP025394|CRT
CCAGGGTCCTTTGGCTCC

CRISPR arrays and Neighbor proteins around NZ_CP025394_6

CRISPR arrays

The CRISPR arrays of NZ_CP025394_6

>merge|NZ_CP025394|6|2810742-2810903|CRT
GGGCCGCCCGGGTCCGGTCCGGCCGGGTCCGGTCCGCTCGGGTGGGGTCCGCCCGGGCGGGGTCCGCTCGGGTGGGGGTCGCCTGGGTCCGGTCCGCCCGGGCGGGGTCTGCTCGGGCCAGGGTCCTTTGGCTCCGGTCCGCCCGGGCGGGGGTCGCTCAGG

>NZ_CP025394|6|1|2810742-2810903|CRT
GGGCCGCCCGGGTCCGGTCCGGCCGGG	TCCGGTCCGCTCGGGTGG
GGTCCGCCCGGGCGGGGTCCGCTCGGG	TGGGGGTCGCCTGGGTCC
GGTCCGCCCGGGCGGGGTCTGCTCGGG	CCAGGGTCCTTTGGCTCC
GGTCCGCCCGGGCGGGGGTCGCTCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104816116.1|2799533_2802143_+|aminopeptidase-N	unknown	unknown	gnl|CDD|274121
NZ_CP025394.1|WP_104816129.1|2825560_2825992_-|fic-family-toxin-antitoxin-system,-toxin-component	unknown	unknown	unknown
NZ_CP025394.1|WP_104816125.1|2819284_2820274_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-succinyltransferase	unknown	unknown	gnl|CDD|274635
NZ_CP025394.1|WP_104816127.1|2822891_2824181_-|biotin-transporter-BioY	unknown	unknown	gnl|CDD|308206
NZ_CP025394.1|WP_104816128.1|2824529_2825354_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|236841
NZ_CP025394.1|WP_104820816.1|2811775_2812186_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350221
NZ_CP025394.1|WP_104816115.1|2798713_2799415_-|DsbA-family-protein	unknown	unknown	gnl|CDD|376526
NZ_CP025394.1|WP_104816119.1|2804037_2805432_-|carbohydrate-ABC-transporter,-N-acetylglucosamine/diacetylchitobiose-binding-protein	unknown	unknown	gnl|CDD|274816
NZ_CP025394.1|WP_104816113.1|2796327_2796927_-|biotin-transporter-BioY	unknown	unknown	gnl|CDD|376871
NZ_CP025394.1|WP_104816117.1|2802215_2803091_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP025394.1|WP_104816121.1|2806995_2807619_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	unknown	unknown	gnl|CDD|274422
NZ_CP025394.1|WP_168219594.1|2817185_2819036_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1	unknown	unknown	gnl|CDD|378889
NZ_CP025394.1|WP_104816120.1|2805585_2806887_-|glycoside-hydrolase-family-18-protein	unknown	unknown	gnl|CDD|119365
NZ_CP025394.1|WP_158702147.1|2820703_2821915_-|hypothetical-protein	unknown	unknown	gnl|CDD|380149
NZ_CP025394.1|WP_104816114.1|2797205_2798609_+|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NZ_CP025394.1|WP_104816124.1|2813168_2814170_-|ornithine-carbamoyltransferase	unknown	unknown	gnl|CDD|179366
NZ_CP025394.1|WP_174805635.1|2814429_2816985_-|polynucleotide-kinase-phosphatase	unknown	unknown	gnl|CDD|274963
NZ_CP025394.1|WP_104816122.1|2807691_2810352_-|aconitate-hydratase-AcnA	unknown	unknown	gnl|CDD|236445
NZ_CP025394.1|WP_104816118.1|2803090_2804023_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP025394.1|WP_104816123.1|2812537_2813074_+|superoxide-dismutase	unknown	unknown	gnl|CDD|376292

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104816116.1|2799533_2802143_+|aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
NZ_CP025394.1|WP_104816125.1|2819284_2820274_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-succinyltransferase	gnl|CDD|274635	TIGR03535, DapD_actino, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. This model represents a clade of the enzyme specific to Actinobacteria. Alternate name: tetrahydrodipicolinate N-succinyltransferase.	1.59136e-170
NZ_CP025394.1|WP_104816127.1|2822891_2824181_-|biotin-transporter-BioY	gnl|CDD|308206	pfam02463, SMC_N, RecF/RecN/SMC N terminal domain. This domain is found at the N-terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.	5.38011e-08
NZ_CP025394.1|WP_104816128.1|2824529_2825354_-|methyltransferase-domain-containing-protein	gnl|CDD|236841	PRK11088, rrmA, 23S rRNA methyltransferase A; Provisional.	4.40306e-46
NZ_CP025394.1|WP_104820816.1|2811775_2812186_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350221	cd09873, PIN_Pae0151-like, VapC-like PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Pyrobaculum aerophilum proteins, Pae0151 and Pae2754, and homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	6.45502e-19
NZ_CP025394.1|WP_104816115.1|2798713_2799415_-|DsbA-family-protein	gnl|CDD|376526	pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyze one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways. This family also contains members with functions other than HCCA isomerisation, such as Kappa family GSTs, whose similarity to HCCA isomerases was not previously recognized. Some members have been annotated as dioxygenases, dehydrogenases, or putative glycerol-3-phosphate transfer proteins, but are most likely HCCA isomerase enzymes.	1.39167e-09
NZ_CP025394.1|WP_104816119.1|2804037_2805432_-|carbohydrate-ABC-transporter,-N-acetylglucosamine/diacetylchitobiose-binding-protein	gnl|CDD|274816	TIGR03851, chitin_NgcE, carbohydrate ABC transporter, N-acetylglucosamine/diacetylchitobiose-binding protein. Members of this protein family are the substrate-binding protein, a lipid-anchored protein of Gram-positive bacteria in all examples found so far, that include NgcE of the chitin-degrader, Streptomyces olivaceoviridis, and close homologs from other species likely to share the same function. NgcE binds both N-acetylglucosamine and the chitin dimer, N,N'-diacetylchitobiose. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	4.79804e-177
NZ_CP025394.1|WP_104816113.1|2796327_2796927_-|biotin-transporter-BioY	gnl|CDD|376871	pfam02632, BioY, BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes.	1.53827e-29
NZ_CP025394.1|WP_104816117.1|2802215_2803091_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.87647e-70
NZ_CP025394.1|WP_104816121.1|2806995_2807619_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme	gnl|CDD|274422	TIGR03083, TIGR03083, uncharacterized Actinobacterial protein TIGR03083. This protein family pulls together several groups of proteins, each very different from the others. They share in common three conserved regions. The first is a region of about 38 amino acids, nearly always at the N-terminus of a protein. This region has a bulky hydrophobic residue, usually Trp, at position 29, and a His residue at position 37 that is invariant, so far, in over 150 instances. The second conserved region has a motif [DE]xxxHxxD. The third conserved region contains a hydrophobic patch and a well-conserved Arg residue. Most examples are found in the Actinobacteria, including the genera Mycobacterium, Corynebacterium, Streptomyces, Nocardia, Frankia, etc. The pattern of near-invariant residues against a backdrop of extreme sequence divergence suggests enzymatic activity and conservation of active site residues.	9.19093e-19
NZ_CP025394.1|WP_168219594.1|2817185_2819036_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1	gnl|CDD|378889	pfam12623, Hen1_L, RNA repair, ligase-Pnkp-associating, region of Hen1. This domain is the N-terminal region of the bacterial Hen1 protein. This protein forms stable hetero-tetramer with Pnkp. The hetero-tetramer was able to repair transfer RNAs cleaved by ribotoxins in vitro. This domain provides the ligase activity of the hetero-tetramer.	6.91597e-149
NZ_CP025394.1|WP_104816120.1|2805585_2806887_-|glycoside-hydrolase-family-18-protein	gnl|CDD|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	1.20714e-131
NZ_CP025394.1|WP_158702147.1|2820703_2821915_-|hypothetical-protein	gnl|CDD|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	0.00556886
NZ_CP025394.1|WP_104816114.1|2797205_2798609_+|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	8.79022e-153
NZ_CP025394.1|WP_104816124.1|2813168_2814170_-|ornithine-carbamoyltransferase	gnl|CDD|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	0
NZ_CP025394.1|WP_174805635.1|2814429_2816985_-|polynucleotide-kinase-phosphatase	gnl|CDD|274963	TIGR04075, Ser/Thr_phosphatase_family_protein, polynucleotide kinase-phosphatase. Members of this protein family are the bacterial polynucleotide kinase-phosphatase (Pnkp) whose genes occur paired with genes for the 3' terminal RNA ribose 2'-O-methyltransferase Hen1. All members of the seed alignment belong to a cassette with the Hen1. The pair acts in bacterial RNA repair. This enzyme performs end-healing reactions on broken RNA, preparing from the RNA ligase to close the break. The working hypothesis is that the combination of Pnkp (RNA repair) and Hen1 (RNA modification) serves to first repair RNA damage from ribotoxins and then perform a modification that prevents the damage from recurring. [Transcription, RNA processing].	0
NZ_CP025394.1|WP_104816122.1|2807691_2810352_-|aconitate-hydratase-AcnA	gnl|CDD|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
NZ_CP025394.1|WP_104816118.1|2803090_2804023_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.62034e-68
NZ_CP025394.1|WP_104816123.1|2812537_2813074_+|superoxide-dismutase	gnl|CDD|376292	pfam00080, Sod_Cu, Copper/zinc superoxide dismutase (SODC). superoxide dismutases (SODs) catalyze the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD1 gene cause familial amyotrophic lateral sclerosis (Lou Gehrig's disease). Structure is an eight-stranded beta sandwich, similar to the immunoglobulin fold.	0.00412584

Protein sequences

>NZ_CP025394.1|WP_104816122.1|2807691_2810352_-|aconitate-hydratase-AcnA
MSANSFDARSSLQVGDESYEIFKLSAVEGSERLPYSLKVLLENLLRTEDGANITADHIRALGNWDASAEPSEEIQFTPARVIMQDFTGVPCVVDLATMREAVKELGGDPAKINPLAPAELVIDHSVIADKFGTKDAFTQNVEIEYGRNKERYQFLRWGQTAFDEFKVVPPGTGIVHQVNIEHLARTVMVRNGQAYPDTCVGTDSHTTMVNGLGVLGWGVGGIEAEAAMLGQPVSMLIPRVVGFKLNGQLPAGTTATDLVLTITEMLRKHGVVGKFVEFYGEGVTSIPLANRATIGNMSPEFGSTCAIFPIDAETINYLKLTGRDEQQLALVEAYAKEQGLWHDPSVEPVYSEYLELDVSTVVPSISGPKRPQDRVVLAEAAAKFAEALPTYSAEASKPTAVTAPDGSSYEIDNGAVVIASITSCTNTSNPSVMLGAALLAKKAVEKGLHVKPWVKTTLAPGSKVVMDYYEKAGLLPYMEKLGFNLVGYGCVTCIGNSGPLPEEVSAAVNASDLAVVSVLSGNRNFEGRINPDVKMNYLASPPLVVAYALAGNMNIDITRDALGQDADGNDVFLADIWPSEQEVADTVAGSIDEAMFDKGYQDVFAGDQRWQSLPVPTGNTFEWDTESTYVRKPPYFEGMAKTPSPVTDIAGARVLAKLGDSVTTDHISPAGNIKPGTPAAQYLTEHGVEKRDFNSYGSRRGNHEVMIRGTFANIRLRNQIAPGTEGGYTRDFTQADAPVSFIYDASQNYQAAGIPLVVLAGKEYGSGSSRDWAAKGTALLGVKAVIAESYERIHRSNLIGMGVLPLQFPAGQNADSLGLTGEETFEFTGVTELNEGRTPKTVKVKAVGPAGTSTEFDAVVRIDTPGEADYYRNGGILQYVLRSLIG
>NZ_CP025394.1|WP_104816121.1|2806995_2807619_-|maleylpyruvate-isomerase-family-mycothiol-dependent-enzyme
MSTDPWALIHAERRALLADVEQLTPEQWRTPSLCAGRSVRDTLAHLAATARMTPPGFFVKLARAGFRFEVMTGREIAELTAGTIDQTVDAFAAQLNSTTHPPGPDDSWLGETVVHGEDIRRPLGIVHAYPEEALTRCADFYRRSNLLIGGKRRVEGLTLRATDARWWAGEGPEVSGPMLELLLAVTGRPAGLAELSGEGLPTLAARM
>NZ_CP025394.1|WP_104816120.1|2805585_2806887_-|glycoside-hydrolase-family-18-protein
MPRRTSALLAAATLAALIVAPATSAQAHDGQGHRGLQGQRVGYFTQWGIYSGFSAKKVQTSGQAGKLTVINYAFGNVSSDGTCFEASGAGVGDPWADYQRPVGAEESVDGVADADAQQVKGNFNQLRKLKAANPQLKSVISLGGWTWSKYFSDAAATDASRKKFVASCLDLYLLGNLPGVTPGAGAGVFDGIDIDWEYPGGGGDPGNVVRPEDGHNYTLLMQEFRRQLDALGRSAHRHYLLTAAVPANETKADRLEIPQVARQVDWLNLMTYDLHGTWESSTDHNANLYSDSADPAVDNRSYSADRVVRHYLAKGLPPHKAVLGVPFYGYGWTGVPAGDKFGLYQTSTGPARGGNLPYNQIKDLPGTVHYDRQHGATWKYDGTEFWSYDTPELLTRKAQYADWHGLAGVMAWALDNDDAQGSLVAALDKGLSG
>NZ_CP025394.1|WP_104816119.1|2804037_2805432_-|carbohydrate-ABC-transporter,-N-acetylglucosamine/diacetylchitobiose-binding-protein
MSTGAGYNRRELLRRAAGLTALAVTGGPLLAACAGGGGGTTGGATAVASSATNPLGVDGSAPLEVVIFKGGFGDDYAKAFEGLYAKTYSAAKITHTPTQDITGLLQPRFNGGSPPDVVDDSGAKQIKLDVLHKAGQLADLTALLDAPYLDDPSRKVRDVLQPGTVEHGSFDGKMYSLNYVYSVSGLWYSGKLFKEKGWTAPKTWAEFITLCGTIKAAGVAPFCHQGKYPYYINVAIMDLLARQGGREIITRVDQLDTTVWDGPEAKAAISAIYQLVDQDYLLPGTNGMTHTEAQTAWNQYKAAFVPCGSWLENEQLKLTPDDFEMTFLPMPSLPGDKLPPTSLRAGADEPFIVPAKAKNVAGGMEFLRMMLTKAGAGQFAQQANAVTVLKDGIGPEVKLRPGTKSAVAALGAAGTEVFNYDYPNTQSAFDIELGNASTELMANRIKPEEWLKRAKAAAEKAKKA
>NZ_CP025394.1|WP_104816118.1|2803090_2804023_-|sugar-ABC-transporter-permease
MRHRRYPFIIGFLVVPVLLYAALVIWPYLQTFGYSLTDWNGQSQQMHFVGLDNYTKLAHDEVFLGALGHNLLLLAVLPVATVLLALFFAFMLNVGGRGGTARVQGVRGAGGYKVLFFLPQVLSVAILAVLWEAVYRPDGGGLFNGVLLKLGLESPGHPVEWLADPDLVLWCILGVLVWAGTGFYLVLFSAAMQSVPRDVYESALLDGAGRPQTFFRITLPLLWDTVQTAWVYLAIAAMDVFALVSTMTVGASYGGGPDHRSEIVATYLMRNFLFFGKAGYACAMGVVIFFFTLVLSVVALRVTRRERIEY
>NZ_CP025394.1|WP_104816117.1|2802215_2803091_-|carbohydrate-ABC-transporter-permease
MAARRERTGPLNVFSHGFLLLWAVLIVLPLLWVVLGSFKNDAEIDGSAWSWPSHWGFAAFGRAWSKGGIGGFFLNTVIVLAGSLTLTMLLGAMAAYVLARYEFPGNRVVYYFFVAGAMFPVYLALVPLFFMVRRLGTISPLLGLNSYLGLILVYVAYSLPFTVFFLHAFLRTLPTAVHEAAMLDGCSHTRAFFQVMLPMARPGLVSVGIFNLLGQWNQYILPVTLMQPTSGTDANRSMLAQGLVNLALQQGYAGDPAALFAGMTIAMLPVLVVYLSFQRQVQVGLTAGTLK
>NZ_CP025394.1|WP_104816116.1|2799533_2802143_+|aminopeptidase-N
MPGKNLTREEAQQRADILTLDSYRVHLDVSAATDPAVATFGSTTTLSFRCSTPGADTFVDLLAPAVRSVTLNGRALDPAEVFDGVRVSVPGLAEQNELVIEADCAYSRTGEGLHRFVDPVDGETYLYTHFEPADSRRVFANFEQPDLKAPFSFTVTAPAAWDVYANAVDERVTAEGAVKVWEFAPTKPISTYLTAVVAGPYHVVRDHYSRKLADGTTLEIPLAATCRKSLARYFDADEILTVTKQGLDYFHEEFDYPYPFGKYDQCFVPEYNIGAMENPGCVTFREEFVFRSKVTDAAYEGRANVILHEMAHMWFGDLVTMKWWDDLWLKESFADFMGSFSQIEATRYQAAWITFANRRKAWAYRQDQFPTTHPITADIRDLEDAKLNFDGITYAKGASVLKQLVAYVGRDAFFEGVRHYFKRHAFGNTVLGDLLEALEATSGRDLTAWAAAWLQTSGVNLLTPQLTCDAEGRITEFAVLQESGTLRPHRLAVGCYDRAEDGTLVRTQRVELDVTGARTVVPELAGRVRPDLVLLNDDDLTYCKIRFDDHSLATLRSSLGDLSDPPSLPADGQEGPSRPGGLARALTWSAVWNLTRDGLMPARDYVDLVLRFAGTESDIGVLQSLHGQAKAALDLYAAPEWRAEGAGLLAECALRELRAAAPGSDHQLAWARFLSQNAGGSEHLQLIRGLLAGTARIDGLEIDQELRWDLWLTLAAASEAQEAELRGELERDNTASGKQHLTHCLAARPTAEAKAAAWAAVVDSDELPNALVEASIAGFNLAGQRELTAGYLEPYFELLETVWAQRSIEIAMRIVGGFFPRYQTTEATLAATDAWLASHPQAAPALRRLVLEGRDDLARALRAQACDQG
>NZ_CP025394.1|WP_104816115.1|2798713_2799415_-|DsbA-family-protein
MPGGPPVLGSVPSTSSERRTPSVTTADSRKIADFWFDPVCPWAWMTSRWMLEVEKLRPVDTRWHVMSLAVLNEHNENLPEQYREAIKKAWGPVRVVIAAAQAHGEKVIGPLYTELGTRFHNQALPNERATIEAALVAAGLPAELADAAESDAYDEALRASHQEGISLVGQDVGTPVIAVDGPDGDRVAFFGPVVTPTPRGEAAARLWDGTVLVASTPGFYEIKRTRTAGPSFE
>NZ_CP025394.1|WP_104816114.1|2797205_2798609_+|amino-acid-permease
MATPTPRPTLAPEGQTTGSGAAGGQLGHGLKPRHLSMIALGGVIGAGLFVGSGAGIAAAGPAIVLAFALSGVLVMLVMRMLGEMSAAHPASGSFSVHAEREIGPWAGLTAGWMYWTLLCVGVAAEAIGASHVMAGWIPAVPSWLWVAVFMAFFCGTNLAAVKNFGEFEFWFAAVKITAIAAFLVICVLAIAGVLPGTSAPGTGNLTGQGGFLPNGTGGLITGLLASVFAYGGLETVTIAAAESEDPRRNVASAVRTAMWRIAVFYIGSMAVIVTLVPWNDPAVVKDGPYVAVLDSLGIPGAGQLMNVVVLIALLSAMNANIYGSSRMAYSLVRRGQGPQALAKVSGGVPRRAVLASCAFGFLAVLFNYWWPTTVFHWLLNMVGAAVLVVWGFIAVAQLRMRRRLEREAPEQLTVRMWLYPYLTWAALAGIAAVLALMTLDADNRVQLYFTAGLAVVLAVIGKVRSGR
>NZ_CP025394.1|WP_104816113.1|2796327_2796927_-|biotin-transporter-BioY
MAIAAVPARTPVLADLLPKAATRLGAQARELTLVGGGAVLTGLAAQLSVHVPGSPVPVTGQTFAALLVGTALGARRGIASLGLYLLAGAAGLPWFAGASSGWAMASFGYVIGFVLAAGLTGALARRGADRSPLRTAGVMVLGNLAVYAVGVPYLALALHVPLARAAELGLYPYLVGDALKALLAMGALPLAWKLIGRRG
>NZ_CP025394.1|WP_104820816.1|2811775_2812186_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MIVVDASALVLSLADHGARGDAARAALAADQDWAAPEHLLIEVMQSLRGRYLAKENTAEEVATIAATLPNLVFHKVALGPLLPRVWELKDNLTPDDAAYVAVAESLGAPLITADLRLARASGPRCEIRGLVRPATA
>NZ_CP025394.1|WP_104816123.1|2812537_2813074_+|superoxide-dismutase
MALPLSVPAALLPLALLPSLAAPATTVDAVFEPASAFLPATAISYAQDLVPYGSRVHVRVVRVDGHTAVALQLSGVAPGRVFPVHAHTGRCGAAPADSGPHYQDQADPVQPSTDPAYANGSNEVRLAVSTDAQGTGSADTTVAWTFRDGGAHSLVLHAGTPSGDHAAADRVACVNVGF
>NZ_CP025394.1|WP_104816124.1|2813168_2814170_-|ornithine-carbamoyltransferase
MAFNLRNRHFLKELDFTPQEFRFLLGLSAQLKAAKYAGTEQPRLRGKNIALIFEKTSTRTRCAFEVAAHDQGATTTYLDPAGSQMGHKESIKDTARVLGRMFDGIEYRGHGQEVVEELAAYAGVPVWNGLTDEWHPTQMLADVLTIQEHSAKPLGEVSLAYLGDARCNTGNSLLVTGALLGMDIRIVAPKQLWPTEDVQKAARALAETTGARITLTEDVAAGVAGADFLYTDVWVSMGEPKEVWAERIDLLKPYQISMETIRATGNPAVKFLHCLPAFHDLGTAIGRQMYEATGMSELEVTDEVFESAHSVVFDQAENRLHTIKAVLVATLGA
>NZ_CP025394.1|WP_174805635.1|2814429_2816985_-|polynucleotide-kinase-phosphatase
MLAVTDISLVVLIGTTGAGKSSFARAHFKPTEVVSSDFCRGLVADDENDQSASADAFDVLHYILGKRLAAGRLTVVDATNVQPEARKQLIRIAREHDVLPIAIVLDIPPAVCAERNRHRLDRQLPPHVIPRQQRELRRSIKGLEREGFRKVHILRGEAEVAAAEVVLEKRFNDLRHLTGPFDIVGDIHGCRAELETLLTRLGYTLGRDEQGRPIDAVPPQGRTAVFVGDLVDRGPDSPGVLRLVMGMVAAGHAVCVPGNHENKLGRWLDGRKVTVSYGLQETIDQLAGESEEFRRQVREFIRGLVSHYLLDGGRLVVCHAGLPEKYHGRASGRVRSHALYGDTTGETDEYGLPVRYPWAEEYRGRALVVYGHTPVPSASFLNNTICLDTGCVFGGSLTALRYPERELVSVEAEQEWYAPVRPLHSDAPGSREGRPLDLADVAGRRVVDTTLHGRISVREENAAAALEVMSRFALDPRLLTYLPPTMAPSATSRREGYLEHPEEAFAAYREDGVRQVVCEEKHMGSRAVVLVARDPAALEKRFGVAGPGAIWTRTGRAFLNDEELTDAVLERVRAAAERAGLFEELATGWLLLDAELMPWSLKAVELLRRQYASVGAAAGAALPTVLTALDQAVARGLDLGELTERQRRRAADAEAFTAAYRRYCWPTEGLNGIRLAPFQVLAAEGANLAVRPHDEHLAWIDRLVEADDPAAPILQTTGRLLVDTSDEESVRAGVAWWEGLTTAGGEGMVVKPLGSLVRGATGKGGQGGLVQPGIKVRGREYLRIIYGPDYTRYLDQLRQRFLGHKRSLALREYALGLEALDRLAAGEPLWRVHEAVFAVLALESEPVDPRL
>NZ_CP025394.1|WP_168219594.1|2817185_2819036_-|3'-terminal-RNA-ribose-2'-O-methyltransferase-Hen1
MFISISTTGTAERPATDLGFLLHKHPDRVQRFDTSHGEAHVFYPEATETACTAALLLDIDPIALVRRGRGKGRGGSPDFALAQYVNDRPYAASSLLAVALRTVFRTAMKGVCEHRPGLAEQPLPLRVSLPAVPVKAAGEGAEVQADGSPAALVRRLFEPLGWQVTAEPVPLDEAFPEWGPSRYVRVELQGTVRLAEALQQLYVLLPVLDGSKHYWVAPDEVDKLLAAGGGWLGEHPELALITRRYLARRWSLTRTAMARLELARLAEADDREAEEFDNAVAESLADEDLADLAAESLRAAGAAAAPDGDGDGVGDEGRTPSTARSGAASATTDDRGEEVREEMTAMATEPDTSDATDPRLDGKPESLTAQRRRAILVALAETGAGRVLDLGCGQGELVEALLKETRVTEVLGVDVSVKALTVAARRLRLDRMPERMAARVKLVQGALTYTDSRLKGYDAAVLSEVIEHVDLPRLPALEYAVFGSAAPTTVVVTTPNVEYNVRWESLPAGQVRHADHRFEWDRATFRAWAERVGRSYGYTVTLRPVGPHDEEVGAPTQLALFRKGVAESRAAIAAPQAAVTVAGAVAVTTTESTIESAAAPAGSTTASAVTEGSVTR
>NZ_CP025394.1|WP_104816125.1|2819284_2820274_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-succinyltransferase
MTAETSTLASGAVASGLATIAADGTVLDTWYPAPKLVAEPGPAGTVRLTAAEADADLGQGASEALRADARRGVEVVAVRTTIASLDEKPIDAHDAYLRLHLLSHRLVRPHGQSLDGLFGLLANVAWTSIGPVPVDQVERARLAVRAQGGQLAVYGIDKFPRMTDYVAPSGVRIAHADRVRLGAHLAVGTTVMHEGFVNFNAGTLGTSMVEGRISAGVVVGDHSDIGGGASIMGTLSGGGKQVVSVGERCLLGANAGIGISLGSDCVVEAGLYVTAGTRVTTPDGKIAKAVELSGQDNLLFRRNSQSGAVEVIARSGSWGGLNAELHAHN
>NZ_CP025394.1|WP_158702147.1|2820703_2821915_-|hypothetical-protein
MEALRLIKTGRHALAQARSVGDVLTEAWQTGMLTELIGARIAEAEEGELGALGQLLCEAGAHAVSSVDQPTMAVADDAEPEPDWHRADWSGQGRAGRMTELGELAPVLAELERLLHEVADSLVVLACGAEGEGLYWRCIDGVDAGSECKDLVAELMRAVRRGQPDETAAAALYGRSELGLDELDLDDLVDLDSIEDLSRSRGLDDLGGQEAETTDVGKTRTGARAADPEPDSDSELAPDLEQDADSTPEAEVASSSASASESGSDSLVDDDEATVVAAGRGPGPGRSRPGPVVERGAEGGVPILLVTLSPPVKGRGYQPEVAGPAELSACPRPSTALVPEDCRSASSPARSALTELSRSCICSSRLLGAAVGAGRTPGVSRGTAGVSDQGSDMRGPLQLGSAV
>NZ_CP025394.1|WP_104816127.1|2822891_2824181_-|biotin-transporter-BioY
MTSEASPGLRSGETQPPATRPVFRPAVEELRLTSFKSYRRTSLPLSPLTVLYGPSGVGKSNAMDSLTVLSRLALGEPIAPSLDGVGGTSGPLATPVRGGLVGCVPHGRNAIILGCTVRSPAGPIRLELVVRTDGPVRVAREWLTCDGRTLMETGEQDVARGRINVTWHNDTRQGDIRAPFPSCSLITSQIPLRVAGSSAGERMVLAASEHLLTALREVFPLHPEPAQMRGWVEHENDARLLGTAANISPVLARLKGECTRRYGKLLKAVQAAAPHPLLGLDVARRGPEARQQLMAVFDEGVLGRTTADQASDGMLRLLAFAAVLLTGAGVLDVDPAVEVPAAHRQLTVLAEDLGAGLAADQVAALLRVAREVCDREDVRLLGALQEPTAAREVGGIELVECRRDPATGHSVLRPETPRVPAQAAGVVGS
>NZ_CP025394.1|WP_104816128.1|2824529_2825354_-|methyltransferase-domain-containing-protein
MLQDIERYLACPHCTQRLALDGRTLRCAAGHSFDQAKQGYVSLLPGDAHTGTGDTAEMVAARSDFLAAGHYQPIVAALAGAAGGPVDGLVADLGAGTGHYLAHVLEHTGGVGAALDISKFALRRAAKAHPRIGAVVCDAWRPLPLQDGCADLVLNVFAPRNGPEIQRILRPGGRLLVVSPTSRHLAELVSALGLLSVDEDKDRRIDEKLGPWLTRTEQVEVDFRLALSQAEAAAVVAMGPNAWHTDAGRLAAALAELGEPVSVTGAVRVTTYTR
>NZ_CP025394.1|WP_104816129.1|2825560_2825992_-|fic-family-toxin-antitoxin-system,-toxin-component
MKLEVDLSWLLMTAEQYTPGDPQVTDYGSLLAAVARHQADIFDIAVYPEPHDRAAALMHQLIRVPALERNNELFATAVAYAYLSASGCSVATTAREVRSLARAIREGKLGVGGVAERLAAWVVDDPEDEEVSGEDDGEEGDAD

Crispr_ID: NZ_CP025394_7

• CRISPR_ID: NZ_CP025394_7
• CRISPR_location: 2876817-2876915
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_7

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGAAC	CRISPRCasFinder

spacers of NZ_CP025394_7

>7.1|2876841|51|NZ_CP025394|CRISPRCasFinder
ACGGAAGAAGCGGCCGGAAATCGCTCCGCAGTGAGCCAGTTGCACACGAAA

CRISPR arrays and Neighbor proteins around NZ_CP025394_7

CRISPR arrays

The CRISPR arrays of NZ_CP025394_7

>merge|NZ_CP025394|7|2876817-2876915|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGAACACGGAAGAAGCGGCCGGAAATCGCTCCGCAGTGAGCCAGTTGCACACGAAAAGGGGCGCGGGGAACTGCGCGACT

>NZ_CP025394|7|6|2876817-2876915|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGAAC	ACGGAAGAAGCGGCCGGAAATCGCTCCGCAGTGAGCCAGTTGCACACGAAA
AGGGGCGCGGGGAACTGCGCGACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104820823.1|2883387_2883678_-|YlxR-family-protein	unknown	unknown	gnl|CDD|377288
NZ_CP025394.1|WP_104816159.1|2876986_2877892_-|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl|CDD|235113
NZ_CP025394.1|WP_104816157.1|2873278_2873662_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104816165.1|2884814_2885369_-|ribosome-maturation-factor-RimP	unknown	unknown	gnl|CDD|234627
NZ_CP025394.1|WP_104816156.1|2872271_2873213_-|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl|CDD|235536
NZ_CP025394.1|WP_104816150.1|2864994_2865288_-|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|227179
NZ_CP025394.1|WP_104816162.1|2879584_2879881_-|DUF503-domain-containing-protein	unknown	unknown	gnl|CDD|377364
NZ_CP025394.1|WP_104816149.1|2863590_2864883_-|type-VII-secretion-associated-serine-protease-mycosin	unknown	unknown	gnl|CDD|274856
NZ_CP025394.1|WP_104816154.1|2869036_2869801_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104816160.1|2877881_2878994_-|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	unknown	unknown	gnl|CDD|223691
NZ_CP025394.1|WP_104816152.1|2865862_2867434_-|type-VII-secretion-protein-EccB	unknown	unknown	gnl|CDD|368288
NZ_CP025394.1|WP_104816167.1|2886833_2887577_+|kinase	unknown	unknown	gnl|CDD|309685
NZ_CP025394.1|WP_104816153.1|2867654_2869037_+|type-VII-secretion-protein-EccE	unknown	unknown	gnl|CDD|274857
NZ_CP025394.1|WP_104816158.1|2873655_2876694_-|serine-protease	unknown	unknown	unknown
NZ_CP025394.1|WP_104816163.1|2880014_2883179_-|translation-initiation-factor-IF-2	unknown	unknown	gnl|CDD|235401
NZ_CP025394.1|WP_104816151.1|2865374_2865680_-|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|274862
NZ_CP025394.1|WP_104816161.1|2878996_2879434_-|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl|CDD|234787
NZ_CP025394.1|WP_104816155.1|2870027_2872112_+|MinD/ParA-family-protein	unknown	unknown	gnl|CDD|223531
NZ_CP025394.1|WP_104816164.1|2883748_2884762_-|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl|CDD|237061
NZ_CP025394.1|WP_104816166.1|2885625_2886633_+|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|373114

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104820823.1|2883387_2883678_-|YlxR-family-protein	gnl|CDD|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	2.09565e-24
NZ_CP025394.1|WP_104816159.1|2876986_2877892_-|tRNA-pseudouridine(55)-synthase-TruB	gnl|CDD|235113	PRK03287, truB, tRNA pseudouridine synthase B; Provisional.	2.4615e-165
NZ_CP025394.1|WP_104816165.1|2884814_2885369_-|ribosome-maturation-factor-RimP	gnl|CDD|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	3.86868e-42
NZ_CP025394.1|WP_104816156.1|2872271_2873213_-|bifunctional-riboflavin-kinase/FAD-synthetase	gnl|CDD|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	1.37522e-146
NZ_CP025394.1|WP_104816150.1|2864994_2865288_-|WXG100-family-type-VII-secretion-target	gnl|CDD|227179	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown].	5.0775e-14
NZ_CP025394.1|WP_104816163.1|2880014_2883179_-|translation-initiation-factor-IF-2	gnl|CDD|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_CP025394.1|WP_104816149.1|2863590_2864883_-|type-VII-secretion-associated-serine-protease-mycosin	gnl|CDD|274856	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin. Members of this family are subtilisin-related serine proteases, found strictly in the Actinobacteria and associated with type VII secretion operons. The designation mycosin is used for members from Mycobacterium. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair].	2.99351e-81
NZ_CP025394.1|WP_104816162.1|2879584_2879881_-|DUF503-domain-containing-protein	gnl|CDD|377364	pfam04456, DUF503, Protein of unknown function (DUF503). Family of hypothetical bacterial proteins.	2.9317e-36
NZ_CP025394.1|WP_104816160.1|2877881_2878994_-|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	gnl|CDD|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	8.27972e-53
NZ_CP025394.1|WP_104816152.1|2865862_2867434_-|type-VII-secretion-protein-EccB	gnl|CDD|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	7.4551e-63
NZ_CP025394.1|WP_104816167.1|2886833_2887577_+|kinase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	3.99811e-35
NZ_CP025394.1|WP_104816153.1|2867654_2869037_+|type-VII-secretion-protein-EccE	gnl|CDD|274857	TIGR03923, T7SS_EccE, type VII secretion protein EccE. This model represents the transmembrane protein EccB of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccE1, EccE2, etc. This model represents a conserved core region, and many members have 200 or more additional C-terminal residues. [Protein fate, Protein and peptide secretion and trafficking].	8.51144e-26
NZ_CP025394.1|WP_104816161.1|2878996_2879434_-|30S-ribosome-binding-factor-RbfA	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	1.48456e-48
NZ_CP025394.1|WP_104816164.1|2883748_2884762_-|transcription-termination/antitermination-protein-NusA	gnl|CDD|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	0
NZ_CP025394.1|WP_104816151.1|2865374_2865680_-|WXG100-family-type-VII-secretion-target	gnl|CDD|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	2.40052e-13
NZ_CP025394.1|WP_104816155.1|2870027_2872112_+|MinD/ParA-family-protein	gnl|CDD|223531	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility].	3.92581e-46
NZ_CP025394.1|WP_104816166.1|2885625_2886633_+|ferritin-like-domain-containing-protein	gnl|CDD|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	2.70966e-23

Protein sequences

>NZ_CP025394.1|WP_104816158.1|2873655_2876694_-|serine-protease
MGLAVVRVCDPDGRVRGLGFVADLSGTVVTAHEVVAGLERVVLHVPGGQTRVLGEGRVEPWPEYGLAVLRTDGVGGLPVPPLAVVGAGGPLVAVPYLRAEAEEPALSQGGVLAGGAAVYPWQGVFHLVEGALLLDLPQLGAPPTAGAPVLDAGTGAVLAVVAPGLRSGHQQGVPAVPLRGAGVAELLARNAATVPAYGRALNLAGVLQLASVQLGSAVAGPGRIADLAADRVDRPDGLTGEEPQCAVTALVGAAGSGRTTELAALTVRRAGGRQPLPTLWLRGADLASGDGSPVPAVARALARAAELLEVAAPEPDEVARICGAAGRPLLVVLDAPEEAQAALTERWFTTCRDWLAEVGARLLLACGPQEWERLAPALPEARPHGLGPLPAEAADRAARRYGLPSGWLGPAEAPHPLALRLAGGLQSEGVRGPAPGRGELFAGHFDLCCLRVARRLAAGTQVRPPGAHRRGAVRPAAERPGQVRRLAAVVAGRLHESARLMLAVGHGGLSRAAFEGLFPEEGGWAAAVLAEGVFVPAGSGYRLAHEEFAEWLQGLHLDLDGALRLLLAEREEPDRAGSPAGADGVGHAWGVPGAGGARSHGVPRHRVGPVVAALRRVAGEPRALDWWLRRLWRALEGAEPGSEGQWWAGRLLAVVLAGLPEPGEHLELLGLLAERGERGGEFGPAFWAGLPLGLADRLGLLRRLVRSDGPEQSFRAATAELLVADPAGVLPLLCGWFEDDSRPAERPGATVADIAHDLLYAHRRLALDNLTECLVDAAHPRADALLSLLAVEEPSALCRAVDRWSHDPRPERHVAAAVHGLRAAPYASGSGGGLLRFAAATLLAREGEPALHGAALALLLRYPESRPRHLARALAAYRADDPFVTAQALAPALAAEPEPVLAALRERLAEPGGAVAEALGLLAEAQDPATVRQGLLLAAELLADHPERADRLAAYADRLLARGHRVTPLLAPLRGQPPAVRRAFAARLARPGPAPGRARWTVCWRGSATRWC
>NZ_CP025394.1|WP_104816157.1|2873278_2873662_-|hypothetical-protein
MLTAVLERTAETCEEHEPRRVRELVRRLAVGGLPLDAALVRSAGRSAAFARLLAEWPAEEPEPGGGPLLARMRELVAEGRDPQYAAAEAERGADGGAAGPAGPLPAQRPPRAAGLPVPKPGRAHGTL
>NZ_CP025394.1|WP_104816156.1|2872271_2873213_-|bifunctional-riboflavin-kinase/FAD-synthetase
MQRWLGLEEIPGDWGRSVVTIGSFDGVHRGHQLIIRRVVERARELGAKAVVVTFDPHPSEVVRPGSHPALLAPQPRRAELMAELGVDAVLVIPFTRELSQQSPEEFVQQVLVDALEARLVIEGPNFRFGHKAAGNVGLLAELGRAADFEVEVIDLKVRGAAGGGEPFSSTLVRRLIAEGDVAAAAEVLGRPHRVEGEVVRGAQRGRELGFPTANVDSVAHSAVPADGVYAGWLTAAGERMPAAISVGTNPTFDGTARTVEAYAIDRVGLDLYGLHVAVDFLAYLRGMEKFDSIEALLDRMADDVKQARDLTGA
>NZ_CP025394.1|WP_104816155.1|2870027_2872112_+|MinD/ParA-family-protein
MSSDRDGVYVGDNAAEDDDDWSDTPDYSPPSWYTQSSTPPAQQAPAAPAPAPAPAPAPDPVAPAAGTPVPGSPVTPAAGTPLWPAPGEAPAPAAPAPGPVETQAPAAPAAPTHLETAGAAAPAAPVGGTPAAGTPSPATPAAGTPVWPAPGEAPAAPVTPAAPAPTAPAAPAAPQPAAPQPAAPQAAQQPPAQGAAPAQPYQQQTPPAPWPPQAGQPGAPLPGGVGPTGVVPVPPVSGAQQLPPQAVPQPGPQQGQPVDPRQGGWPQAPQPGAYPPPQQGGGYPQQAMPQAPQAFQQQGGPQQQVAHGAALGYTAAVELSSDRLLRGQPKQQKESRFKFGGKAAEADRARKLEIIRTPVLSCYRIAVISLKGGVGKTTTTTSLGATLATERQDKVIAIDANPDAGTLGRRVKRQTGATIRDLVTAIPHLRSYMDVRQFTSQDLHSGLEILANDVDPAVSTTFNDSDYRQVIQVLGQHYPIILTDSGTGLLYSAMRGVLDLADQLIIVSTPSVDGASSASTTLDWLSAHGYADLVQRSITVVSGVRETSKMIKVEDIVAHFQTRCRGVVVVPFDESLAAGAEVNLAMMRPKVRDAYFELATLVGEDIARAQHAAGGGWQQQPQQGGYPGYPGQPQQGYPGYPQQGGYPQQGAPWGQQPPQQQYPPQQQGQALPQEWSQQGQQQQPGYGYPPTQQQ
>NZ_CP025394.1|WP_104816154.1|2869036_2869801_+|hypothetical-protein
MAYQTYPTHAPEPGTEPGRTPLLRPGFGLRGPRRERHVLAREDLAALSFPVGDDGVVIGVDPQQQPAVLGLFRPNPYELVLVGGMWTAQIIALRAAATGARIAVETGRPQAWAPMAQAAGGGQPCVTIHQAGRLGAQGASVASPVLVVRDLGARPPRSRLSAAPWQTTLTVLPYLGPNANRVLGAADLVGIQRVSPQEAELLARLLSLGDQEVAALPTLGDNITLWATRMRRQFVMTNPGEAEAQVLGLARRMD
>NZ_CP025394.1|WP_104816153.1|2867654_2869037_+|type-VII-secretion-protein-EccE
MPSQTAPERRSTGHGRRGGHSGGSGRRAQPAQGSPTAPVQVKLHPRPGLLGSRLQLQQLVLLEVAVALVAAGWAISPAVAAICVVPAVLLLVMALLPLGGRSLPEALRVRAEYNARRKRSAANVPPPGTDPALAPVLEVEPALRTCTHATETDLGGGRPMRRETGMVGDGTFLTSVLLVQAKDQPLRPHRTALPLPLDVICSALEVDDITLASVQLVQHTQPAPAPHLPEQSLAARAYHQLPDGLATPGLRLTWVALRLDPERSATAVLARGGGEEGARKALQRVTDQLAGRLNGAGFTANALDERELIAALSISTCANPIAVAGRQGTGGGGGTTRRTQESRKFWRIDDRWHGTYWISKWPQLGRPGGAPGRIAAPDLVNLVTGTPALASTFSLTATAGTGGSLAIQGHVRVTGRSESEVDQVGRLVESRAQHAGAGLTRLDLEQAPGLLATLPLGGTS
>NZ_CP025394.1|WP_104816152.1|2865862_2867434_-|type-VII-secretion-protein-EccB
MASRRDELNAYTFARKRMVGAFLQPSGGGNDEDAPRPVKAVLPSVVVAAVLVAGFGMLGVVSPTAPQGWDDTKNIIQGRDSTTRYVVLVDPVTKEKQLHQVLNMASARLVTPANAKIVIVADNVLDAYKNHGPTIGIPYAPDKLPTPDVAAAAKKWSVCDKAGSDNTQATINQSVFVTVDKEAAQLEKPGKKLAAGEWLFVAEPDTTANRGAWYLVDSGGFKHAIGRVDTSAGDRLALAGAVFGAAKPQQVTKEWLDTLKDGERIDYPVVPGYTGRKVASSLKLTNPDDQYVGRVLTYQGTSFYAVGKDQLFEISPFQAYMIGKSPAAAVLYGDVPEVKPAQLSQTDYGKYASQVDSQTMLKPKGDLPREKPSGHPVNVLADGQGRTVLCSTFESMDDSGNTAQSVFADAQYPAEVASGSSSAHVSPGAGLVFRASEGGQNGSGSNFLLTETGLRYQLKANTADGAKSTGTTGQQQAPQQGDGAQARLGYDKIQPVMVPNAWAALVPAGPVLDVNAAAKPQNY
>NZ_CP025394.1|WP_104816151.1|2865374_2865680_-|WXG100-family-type-VII-secretion-target
MAGQFKTTAEEMNAFANRIGEVNAQVQGEIQRLNTLVDEIKSGWQGAAATAYGQLQARFNEDATALNKVLDEIKQAIEATTKLYAATEQEQQSSMSHAGGF
>NZ_CP025394.1|WP_104816150.1|2864994_2865288_-|WXG100-family-type-VII-secretion-target
MSDSHILVSFSTIQNAAGEVRQTASRIQQQLDELKAGVTRIAASWEGAAQEGYQARQAQWDAKAADLQQALGQIASSLDNAAQSYQATEQKNAGLWG
>NZ_CP025394.1|WP_104816149.1|2863590_2864883_-|type-VII-secretion-associated-serine-protease-mycosin
MGGYRRSGAALVALGVVGGLAAGPAYADDSAKSTARWTPLVVSAAAECAVPSLDVQGVPWSLQRVLLNQLWLPDTSLPVNERKPIDGTNVKVAVIDTGVDNANPQLAGAGKVIDGGAYIKKDGKEDNGSGIGDPVGHGTKVAGIIAASPFAQTGFVGLAPGAQIIAIRQNDAEGNGDVPHLVQAINRAVALGAGVINISQDVRGTDSSGKLFDGKDDLEYALKKAEAAGVVVVASSGNDGLEGETYPAAFSTVLAVGASDRNNERASFSQYGSFVGVAAPGVDMLSTARVHGQCVDNGTSFSSPYVAGVAALLKQKYPKWTPRQIRTRIEQTAERNGRDRNDYTGWGVVDPVKAVQSTAEPADEPTPDAAVQIDSARIVAMPLGLAETQQDRDRRTALYVVAVGLLTVAGLGGGSVVLRDRRKTRSGEGG
>NZ_CP025394.1|WP_104816159.1|2876986_2877892_-|tRNA-pseudouridine(55)-synthase-TruB
MKRKGTGPDGLVIVDKPEGITSHGVVAKLRWLAGTRKVGHAGTLDPMATGVLVIGVERATRLLGHLMLTAKTYEATVRLGQDTVTDDREGEVTSSTDASGVSREAIEAGIAKLTGEIMQVPSKVSAIKIDGKRSYSRVREGEEFEIPARPTTIHSFTVHDQRSAVAEDGTPVIDLDVTVECSSGTYIRALARDLGADLGVGGHLTALRRTKVGPYEVQSARTLEELEEKLEVLPIAEAAAAAFPRWDIDAEQAKLLSNGMRLPAPGLGADGPVAVFGPDGTFLALIEESGGKAKPVAVFVG
>NZ_CP025394.1|WP_104816160.1|2877881_2878994_-|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA
MTAEPVRTGQGAPTTDTVEGALAVLPGPRTEPPSGLELEWQRVVALIGSAASIDLICHISPDGDALGSALAAGLALRSLGHEVRVSFGDDPQIVPESLGFLPGQELLVPAAEVPDAPELALCFDVAAESRLGLLHAKAFAAKAMVVFDHHASNPGFGTHRLIDPGAPATAVLVDELLRRLGVPLDQALATCLYTGVATDTGSFKYAATTPATHELAGRLLATGIRHDLISRRLWDTSSFGYLKVLAAALDRAVYEPEAAGGRGLVWTWVPYQDLALFGVTVEEIEGLIDVLRRPAEAEVALVLKQDPDGTLRGSCRAKGAVDVAAACAELGGGGHRFAAGFAVREEVPAVVRRFRTALLSHICTESTDEA
>NZ_CP025394.1|WP_104816161.1|2878996_2879434_-|30S-ribosome-binding-factor-RbfA
MTDTARARKLADRIKVVVAETLQRRVKDPRLGYVTITDTRVTGDLREATVFYTVYGDELEREASAAALESAKGVLRSEVGRQTGVRFTPTLTFVADALPDNAKNIDDLLDKARLSDAAVRTAAAGASYAGDADPYRTPKADDEDE
>NZ_CP025394.1|WP_104816162.1|2879584_2879881_-|DUF503-domain-containing-protein
MFVGTLTFDLLLGDVHSLKEKRSIVRPIVAELQRKYSVCAAETGNQDLHRRAEIGLAVVSGEAGYVTEVLDSCERLVAGRPEVQLLSARRRYHGDDDD
>NZ_CP025394.1|WP_104816163.1|2880014_2883179_-|translation-initiation-factor-IF-2
MAKVRVYELAKELGLESKAVMAKLTELGEFVRSASSTIEAPVVRKLTDALGVAPTGGSAAKPGPRKPAAPQPAGGASAPKPGAPTPGPRPAATPGPRPTPAPAAPAAAAPAAPAAPAAPKPAVTPGPRPAARPAAPAAPAAEFSSPAPAGEAPARPATPPARPAAAAPGSGARPGPRPAGPRPGNNPFTSGSATGMGRPGDRRPAAPGDRPRPAGAPGAAGERPRPGGDRPRPAGAPGADRGAPRPGGDRGPRPDGTAGARPGADRGAPRPGGDRPRPAAGPGGAPRPGGPGAPRPDGMPRPAGPRPGGPSPSGMPRPNPGMMPQRPAPGAGPRPGPGGRGPGGPGGRPGGPGAGGARPGFQGRPAGPGSRPAGGGGFGGPRPGGAGGGGGFGGPRPGGFGGRPGGPGARGGTQGAFGRGPGGRPARGRKSKRQRRQEYEAMQAPSVGGVMLPRGNGQTVRLSRGASLMDFAEKINANPAALVSVMFNLGEMVTATQSVSDATLELLAGEMGFVLEIVSRDDEDRELLESFDIDFGADEGDEEMLVARPPVVTVMGHVDHGKTRLLDAIRKSNVVAGEAGGITQHIGAYQVSAVVNGEERPITFLDTPGHEAFSAMRARGAKSTDIAILVVAANDGVMPQTVEALNHAKAAGVPIVVAVNKIDVEGADPTKVRGQLTEFGLVAEEYGGDTMFVDISARQGLHIDQLLEAVVLTADASLDLRANPEQDAQGIAIEAHLDKGRGAMATVLVQRGTLRVGDSIVVGDAYGRVRAMLDENGNNLEEAGPSRPVLLLGLTSVPRAGDSFIVVDEDRTARQIAEKRSARDRNAAFAQRRVRISLEDLDKAIAAGSIEQLNLIIKGDVSGSVEALEDALVKLDVGEEVELRVLHRGVGAITESDVDLAMGSDAIIIGFNVRAEGRARTAAEKEGVDVRYYSVIYQAIEEIEAALKGLLKPEYEEVRLGSAEIREVFRSSKFGNIAGVIVREGLLRRNAKARLIRDGKVITENLTIEGLRRFKDDATEVREGFEAGVTLGSFNDIKVEDVIETYEMREKPRS
>NZ_CP025394.1|WP_104820823.1|2883387_2883678_-|YlxR-family-protein
MSGRTHVRACPERTCVGCRKRAAKHQLLRVVAIEGECVPDGRGALPGRGAHLHPDLACLDLAVRRRAFPRAFRLQGALGTDVLRAYVEQAGGTSAF
>NZ_CP025394.1|WP_104816164.1|2883748_2884762_-|transcription-termination/antitermination-protein-NusA
MDIDMSALRGLVTEKNIPFELLVESIESALLIAYHRTEGSRRRARVELNRKSGHVTVWALEDAAELEEGVEPKEFDDTPSGFGRIAASTAKQVILQRLRDAADDQTFGEYAGKEGDIVTGVVQQGNDPKNILVDIGKLEAILPPQEQVPGEDYRHGTRLRCYVVAVRRGVRGASVTLSRTHPNLVKKLFALEVPEIADGSVEIASIAREAGHRTKIAVWSRRQGLNAKGACIGPMGGRVRNVMAELHGEKIDIVDWSEDPAEMVAAALSPARVTKVEIVDYAQRSARVIVPDYQLSLAIGKEGQNARLAARLTGWRIDIRPDTEPADGGPVEGSADA
>NZ_CP025394.1|WP_104816165.1|2884814_2885369_-|ribosome-maturation-factor-RimP
MSTNPTDRLRELLEPLAAAAGLDLEDVKVTQQGSRRQVQVDVDADGGVDLDAVADFSHLVSQALDDSNLMGDAPYVLEVGSPGAERPLALPRHWARAEGRLAKIHLVDGGEIVARVLESDEDGALVEVQPVKGRGKPKERRLEFAEVARARVQVEFNRKEDEHVLQAVESAEDTVDDASDEDDE
>NZ_CP025394.1|WP_104816166.1|2885625_2886633_+|ferritin-like-domain-containing-protein
MLSPNRRTFLALGVLTGALVVSGCSGGSGGGGGGGHKADPDLPLRARAVAATDTLLAGYDAVLAGPGAAQAEQLKALRTEVAAHRTALATGLPAPSGTAAASPSALPAATGTGTAPGSVAALAALEHSTAESRLADLDAASPALAKLLAAVATSDALHAATLGDQSPVTAPKADAPTAGPAASASAAATTSAKAAPKPSAEATALQTALAAEHAAVYGYGVIGGHLPAGAQREDGHASYAAHQAQRDAWQRLLADGGATPTAAAAGYRLPTAVTSPATAADLAVHIEAQLTAVYADLVAATTGPLRQTAAEALRNTAFRARHWGGALPALPGVIG
>NZ_CP025394.1|WP_104816167.1|2886833_2887577_+|kinase
MLDEWLVRWQLTLDRVCVPGHRGGVTALVRQADGTPAVLKLGPAEHEAAALRRWNGQGAVLLLKAEPGALLLERLHADIPLRSLAEPKAVLEATSLLRHLWVEPDGEHVFPELAEHLGPLVEEARETAEELLAGQAERLLLHGALDHGHVLAADRAPWLAISPDPVIGERAYDLAWLALDRLETLIGSPGPKGAARRRITRLAEAVEVDPDRLRGWTLYRATATGLRHLGADQDRLGELYLEFASWL

Crispr_ID: NZ_CP025394_8

• CRISPR_ID: NZ_CP025394_8
• CRISPR_location: 2882371-2882444
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_8

Consensus_repeat	Method
CGCGGGGCGCCACGGTCGGCACCCGG	CRISPRCasFinder

spacers of NZ_CP025394_8

>8.1|2882397|22|NZ_CP025394|CRISPRCasFinder
CCGTGCACCGGCGGTCCCATCG

CRISPR arrays and Neighbor proteins around NZ_CP025394_8

CRISPR arrays

The CRISPR arrays of NZ_CP025394_8

>merge|NZ_CP025394|8|2882371-2882444|CRISPRCasFinder
CGCGGGGCGCCACGGTCGGCACCCGGCCGTGCACCGGCGGTCCCATCGGGACGGGGGCCGCGGTCGCCACCGGG

>NZ_CP025394|8|7|2882371-2882444|CRISPRCasFinder
CGCGGGGCGCCACGGTCGGCACCCGG	CCGTGCACCGGCGGTCCCATCG
GGACGGGGGCCGCGGTCGCCACCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104820823.1|2883387_2883678_-|YlxR-family-protein	unknown	unknown	gnl|CDD|377288
NZ_CP025394.1|WP_104816159.1|2876986_2877892_-|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl|CDD|235113
NZ_CP025394.1|WP_104816157.1|2873278_2873662_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104816156.1|2872271_2873213_-|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl|CDD|235536
NZ_CP025394.1|WP_104816165.1|2884814_2885369_-|ribosome-maturation-factor-RimP	unknown	unknown	gnl|CDD|234627
NZ_CP025394.1|WP_104816164.1|2883748_2884762_-|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl|CDD|237061
NZ_CP025394.1|WP_104816171.1|2890573_2891881_-|site-2-protease-family-protein	unknown	unknown	gnl|CDD|308008
NZ_CP025394.1|WP_104816154.1|2869036_2869801_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104816162.1|2879584_2879881_-|DUF503-domain-containing-protein	unknown	unknown	gnl|CDD|377364
NZ_CP025394.1|WP_104816169.1|2888268_2889144_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379120
NZ_CP025394.1|WP_104816167.1|2886833_2887577_+|kinase	unknown	unknown	gnl|CDD|309685
NZ_CP025394.1|WP_104816153.1|2867654_2869037_+|type-VII-secretion-protein-EccE	unknown	unknown	gnl|CDD|274857
NZ_CP025394.1|WP_104816158.1|2873655_2876694_-|serine-protease	unknown	unknown	unknown
NZ_CP025394.1|WP_104820824.1|2891917_2893147_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl|CDD|235472
NZ_CP025394.1|WP_104816168.1|2887549_2888134_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP025394.1|WP_104816161.1|2878996_2879434_-|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl|CDD|234787
NZ_CP025394.1|WP_104816155.1|2870027_2872112_+|MinD/ParA-family-protein	unknown	unknown	gnl|CDD|223531
NZ_CP025394.1|WP_104816170.1|2889268_2890429_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl|CDD|234737
NZ_CP025394.1|WP_104816166.1|2885625_2886633_+|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|373114
NZ_CP025394.1|WP_104816160.1|2877881_2878994_-|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	unknown	unknown	gnl|CDD|223691

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104820823.1|2883387_2883678_-|YlxR-family-protein	gnl|CDD|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	2.09565e-24
NZ_CP025394.1|WP_104816159.1|2876986_2877892_-|tRNA-pseudouridine(55)-synthase-TruB	gnl|CDD|235113	PRK03287, truB, tRNA pseudouridine synthase B; Provisional.	2.4615e-165
NZ_CP025394.1|WP_104816156.1|2872271_2873213_-|bifunctional-riboflavin-kinase/FAD-synthetase	gnl|CDD|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	1.37522e-146
NZ_CP025394.1|WP_104816164.1|2883748_2884762_-|transcription-termination/antitermination-protein-NusA	gnl|CDD|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	0
NZ_CP025394.1|WP_104816171.1|2890573_2891881_-|site-2-protease-family-protein	gnl|CDD|308008	pfam02163, Peptidase_M50, Peptidase family M50.	8.13955e-47
NZ_CP025394.1|WP_104816165.1|2884814_2885369_-|ribosome-maturation-factor-RimP	gnl|CDD|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	3.86868e-42
NZ_CP025394.1|WP_104816162.1|2879584_2879881_-|DUF503-domain-containing-protein	gnl|CDD|377364	pfam04456, DUF503, Protein of unknown function (DUF503). Family of hypothetical bacterial proteins.	2.9317e-36
NZ_CP025394.1|WP_104816167.1|2886833_2887577_+|kinase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	3.99811e-35
NZ_CP025394.1|WP_104816153.1|2867654_2869037_+|type-VII-secretion-protein-EccE	gnl|CDD|274857	TIGR03923, T7SS_EccE, type VII secretion protein EccE. This model represents the transmembrane protein EccB of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccE1, EccE2, etc. This model represents a conserved core region, and many members have 200 or more additional C-terminal residues. [Protein fate, Protein and peptide secretion and trafficking].	8.51144e-26
NZ_CP025394.1|WP_104816161.1|2878996_2879434_-|30S-ribosome-binding-factor-RbfA	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	1.48456e-48
NZ_CP025394.1|WP_104820824.1|2891917_2893147_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl|CDD|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
NZ_CP025394.1|WP_104816168.1|2887549_2888134_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.06393e-07
NZ_CP025394.1|WP_104816169.1|2888268_2889144_-|GNAT-family-N-acetyltransferase	gnl|CDD|379120	pfam13312, DUF4081, Domain of unknown function (DUF4081). This domain is often found N-terminal to the GNAT acetyltransferase domain, pfam00583 and FR47, pfam08445.	6.44447e-47
NZ_CP025394.1|WP_104816155.1|2870027_2872112_+|MinD/ParA-family-protein	gnl|CDD|223531	COG0455, flhG, Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility].	3.92581e-46
NZ_CP025394.1|WP_104816170.1|2889268_2890429_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl|CDD|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
NZ_CP025394.1|WP_104816166.1|2885625_2886633_+|ferritin-like-domain-containing-protein	gnl|CDD|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	2.70966e-23
NZ_CP025394.1|WP_104816160.1|2877881_2878994_-|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA	gnl|CDD|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	8.27972e-53

Protein sequences

>NZ_CP025394.1|WP_104816162.1|2879584_2879881_-|DUF503-domain-containing-protein
MFVGTLTFDLLLGDVHSLKEKRSIVRPIVAELQRKYSVCAAETGNQDLHRRAEIGLAVVSGEAGYVTEVLDSCERLVAGRPEVQLLSARRRYHGDDDD
>NZ_CP025394.1|WP_104816161.1|2878996_2879434_-|30S-ribosome-binding-factor-RbfA
MTDTARARKLADRIKVVVAETLQRRVKDPRLGYVTITDTRVTGDLREATVFYTVYGDELEREASAAALESAKGVLRSEVGRQTGVRFTPTLTFVADALPDNAKNIDDLLDKARLSDAAVRTAAAGASYAGDADPYRTPKADDEDE
>NZ_CP025394.1|WP_104816160.1|2877881_2878994_-|bifunctional-oligoribonuclease/PAP-phosphatase-NrnA
MTAEPVRTGQGAPTTDTVEGALAVLPGPRTEPPSGLELEWQRVVALIGSAASIDLICHISPDGDALGSALAAGLALRSLGHEVRVSFGDDPQIVPESLGFLPGQELLVPAAEVPDAPELALCFDVAAESRLGLLHAKAFAAKAMVVFDHHASNPGFGTHRLIDPGAPATAVLVDELLRRLGVPLDQALATCLYTGVATDTGSFKYAATTPATHELAGRLLATGIRHDLISRRLWDTSSFGYLKVLAAALDRAVYEPEAAGGRGLVWTWVPYQDLALFGVTVEEIEGLIDVLRRPAEAEVALVLKQDPDGTLRGSCRAKGAVDVAAACAELGGGGHRFAAGFAVREEVPAVVRRFRTALLSHICTESTDEA
>NZ_CP025394.1|WP_104816159.1|2876986_2877892_-|tRNA-pseudouridine(55)-synthase-TruB
MKRKGTGPDGLVIVDKPEGITSHGVVAKLRWLAGTRKVGHAGTLDPMATGVLVIGVERATRLLGHLMLTAKTYEATVRLGQDTVTDDREGEVTSSTDASGVSREAIEAGIAKLTGEIMQVPSKVSAIKIDGKRSYSRVREGEEFEIPARPTTIHSFTVHDQRSAVAEDGTPVIDLDVTVECSSGTYIRALARDLGADLGVGGHLTALRRTKVGPYEVQSARTLEELEEKLEVLPIAEAAAAAFPRWDIDAEQAKLLSNGMRLPAPGLGADGPVAVFGPDGTFLALIEESGGKAKPVAVFVG
>NZ_CP025394.1|WP_104816158.1|2873655_2876694_-|serine-protease
MGLAVVRVCDPDGRVRGLGFVADLSGTVVTAHEVVAGLERVVLHVPGGQTRVLGEGRVEPWPEYGLAVLRTDGVGGLPVPPLAVVGAGGPLVAVPYLRAEAEEPALSQGGVLAGGAAVYPWQGVFHLVEGALLLDLPQLGAPPTAGAPVLDAGTGAVLAVVAPGLRSGHQQGVPAVPLRGAGVAELLARNAATVPAYGRALNLAGVLQLASVQLGSAVAGPGRIADLAADRVDRPDGLTGEEPQCAVTALVGAAGSGRTTELAALTVRRAGGRQPLPTLWLRGADLASGDGSPVPAVARALARAAELLEVAAPEPDEVARICGAAGRPLLVVLDAPEEAQAALTERWFTTCRDWLAEVGARLLLACGPQEWERLAPALPEARPHGLGPLPAEAADRAARRYGLPSGWLGPAEAPHPLALRLAGGLQSEGVRGPAPGRGELFAGHFDLCCLRVARRLAAGTQVRPPGAHRRGAVRPAAERPGQVRRLAAVVAGRLHESARLMLAVGHGGLSRAAFEGLFPEEGGWAAAVLAEGVFVPAGSGYRLAHEEFAEWLQGLHLDLDGALRLLLAEREEPDRAGSPAGADGVGHAWGVPGAGGARSHGVPRHRVGPVVAALRRVAGEPRALDWWLRRLWRALEGAEPGSEGQWWAGRLLAVVLAGLPEPGEHLELLGLLAERGERGGEFGPAFWAGLPLGLADRLGLLRRLVRSDGPEQSFRAATAELLVADPAGVLPLLCGWFEDDSRPAERPGATVADIAHDLLYAHRRLALDNLTECLVDAAHPRADALLSLLAVEEPSALCRAVDRWSHDPRPERHVAAAVHGLRAAPYASGSGGGLLRFAAATLLAREGEPALHGAALALLLRYPESRPRHLARALAAYRADDPFVTAQALAPALAAEPEPVLAALRERLAEPGGAVAEALGLLAEAQDPATVRQGLLLAAELLADHPERADRLAAYADRLLARGHRVTPLLAPLRGQPPAVRRAFAARLARPGPAPGRARWTVCWRGSATRWC
>NZ_CP025394.1|WP_104816157.1|2873278_2873662_-|hypothetical-protein
MLTAVLERTAETCEEHEPRRVRELVRRLAVGGLPLDAALVRSAGRSAAFARLLAEWPAEEPEPGGGPLLARMRELVAEGRDPQYAAAEAERGADGGAAGPAGPLPAQRPPRAAGLPVPKPGRAHGTL
>NZ_CP025394.1|WP_104816156.1|2872271_2873213_-|bifunctional-riboflavin-kinase/FAD-synthetase
MQRWLGLEEIPGDWGRSVVTIGSFDGVHRGHQLIIRRVVERARELGAKAVVVTFDPHPSEVVRPGSHPALLAPQPRRAELMAELGVDAVLVIPFTRELSQQSPEEFVQQVLVDALEARLVIEGPNFRFGHKAAGNVGLLAELGRAADFEVEVIDLKVRGAAGGGEPFSSTLVRRLIAEGDVAAAAEVLGRPHRVEGEVVRGAQRGRELGFPTANVDSVAHSAVPADGVYAGWLTAAGERMPAAISVGTNPTFDGTARTVEAYAIDRVGLDLYGLHVAVDFLAYLRGMEKFDSIEALLDRMADDVKQARDLTGA
>NZ_CP025394.1|WP_104816155.1|2870027_2872112_+|MinD/ParA-family-protein
MSSDRDGVYVGDNAAEDDDDWSDTPDYSPPSWYTQSSTPPAQQAPAAPAPAPAPAPAPDPVAPAAGTPVPGSPVTPAAGTPLWPAPGEAPAPAAPAPGPVETQAPAAPAAPTHLETAGAAAPAAPVGGTPAAGTPSPATPAAGTPVWPAPGEAPAAPVTPAAPAPTAPAAPAAPQPAAPQPAAPQAAQQPPAQGAAPAQPYQQQTPPAPWPPQAGQPGAPLPGGVGPTGVVPVPPVSGAQQLPPQAVPQPGPQQGQPVDPRQGGWPQAPQPGAYPPPQQGGGYPQQAMPQAPQAFQQQGGPQQQVAHGAALGYTAAVELSSDRLLRGQPKQQKESRFKFGGKAAEADRARKLEIIRTPVLSCYRIAVISLKGGVGKTTTTTSLGATLATERQDKVIAIDANPDAGTLGRRVKRQTGATIRDLVTAIPHLRSYMDVRQFTSQDLHSGLEILANDVDPAVSTTFNDSDYRQVIQVLGQHYPIILTDSGTGLLYSAMRGVLDLADQLIIVSTPSVDGASSASTTLDWLSAHGYADLVQRSITVVSGVRETSKMIKVEDIVAHFQTRCRGVVVVPFDESLAAGAEVNLAMMRPKVRDAYFELATLVGEDIARAQHAAGGGWQQQPQQGGYPGYPGQPQQGYPGYPQQGGYPQQGAPWGQQPPQQQYPPQQQGQALPQEWSQQGQQQQPGYGYPPTQQQ
>NZ_CP025394.1|WP_104816154.1|2869036_2869801_+|hypothetical-protein
MAYQTYPTHAPEPGTEPGRTPLLRPGFGLRGPRRERHVLAREDLAALSFPVGDDGVVIGVDPQQQPAVLGLFRPNPYELVLVGGMWTAQIIALRAAATGARIAVETGRPQAWAPMAQAAGGGQPCVTIHQAGRLGAQGASVASPVLVVRDLGARPPRSRLSAAPWQTTLTVLPYLGPNANRVLGAADLVGIQRVSPQEAELLARLLSLGDQEVAALPTLGDNITLWATRMRRQFVMTNPGEAEAQVLGLARRMD
>NZ_CP025394.1|WP_104816153.1|2867654_2869037_+|type-VII-secretion-protein-EccE
MPSQTAPERRSTGHGRRGGHSGGSGRRAQPAQGSPTAPVQVKLHPRPGLLGSRLQLQQLVLLEVAVALVAAGWAISPAVAAICVVPAVLLLVMALLPLGGRSLPEALRVRAEYNARRKRSAANVPPPGTDPALAPVLEVEPALRTCTHATETDLGGGRPMRRETGMVGDGTFLTSVLLVQAKDQPLRPHRTALPLPLDVICSALEVDDITLASVQLVQHTQPAPAPHLPEQSLAARAYHQLPDGLATPGLRLTWVALRLDPERSATAVLARGGGEEGARKALQRVTDQLAGRLNGAGFTANALDERELIAALSISTCANPIAVAGRQGTGGGGGTTRRTQESRKFWRIDDRWHGTYWISKWPQLGRPGGAPGRIAAPDLVNLVTGTPALASTFSLTATAGTGGSLAIQGHVRVTGRSESEVDQVGRLVESRAQHAGAGLTRLDLEQAPGLLATLPLGGTS
>NZ_CP025394.1|WP_104820823.1|2883387_2883678_-|YlxR-family-protein
MSGRTHVRACPERTCVGCRKRAAKHQLLRVVAIEGECVPDGRGALPGRGAHLHPDLACLDLAVRRRAFPRAFRLQGALGTDVLRAYVEQAGGTSAF
>NZ_CP025394.1|WP_104816164.1|2883748_2884762_-|transcription-termination/antitermination-protein-NusA
MDIDMSALRGLVTEKNIPFELLVESIESALLIAYHRTEGSRRRARVELNRKSGHVTVWALEDAAELEEGVEPKEFDDTPSGFGRIAASTAKQVILQRLRDAADDQTFGEYAGKEGDIVTGVVQQGNDPKNILVDIGKLEAILPPQEQVPGEDYRHGTRLRCYVVAVRRGVRGASVTLSRTHPNLVKKLFALEVPEIADGSVEIASIAREAGHRTKIAVWSRRQGLNAKGACIGPMGGRVRNVMAELHGEKIDIVDWSEDPAEMVAAALSPARVTKVEIVDYAQRSARVIVPDYQLSLAIGKEGQNARLAARLTGWRIDIRPDTEPADGGPVEGSADA
>NZ_CP025394.1|WP_104816165.1|2884814_2885369_-|ribosome-maturation-factor-RimP
MSTNPTDRLRELLEPLAAAAGLDLEDVKVTQQGSRRQVQVDVDADGGVDLDAVADFSHLVSQALDDSNLMGDAPYVLEVGSPGAERPLALPRHWARAEGRLAKIHLVDGGEIVARVLESDEDGALVEVQPVKGRGKPKERRLEFAEVARARVQVEFNRKEDEHVLQAVESAEDTVDDASDEDDE
>NZ_CP025394.1|WP_104816166.1|2885625_2886633_+|ferritin-like-domain-containing-protein
MLSPNRRTFLALGVLTGALVVSGCSGGSGGGGGGGHKADPDLPLRARAVAATDTLLAGYDAVLAGPGAAQAEQLKALRTEVAAHRTALATGLPAPSGTAAASPSALPAATGTGTAPGSVAALAALEHSTAESRLADLDAASPALAKLLAAVATSDALHAATLGDQSPVTAPKADAPTAGPAASASAAATTSAKAAPKPSAEATALQTALAAEHAAVYGYGVIGGHLPAGAQREDGHASYAAHQAQRDAWQRLLADGGATPTAAAAGYRLPTAVTSPATAADLAVHIEAQLTAVYADLVAATTGPLRQTAAEALRNTAFRARHWGGALPALPGVIG
>NZ_CP025394.1|WP_104816167.1|2886833_2887577_+|kinase
MLDEWLVRWQLTLDRVCVPGHRGGVTALVRQADGTPAVLKLGPAEHEAAALRRWNGQGAVLLLKAEPGALLLERLHADIPLRSLAEPKAVLEATSLLRHLWVEPDGEHVFPELAEHLGPLVEEARETAEELLAGQAERLLLHGALDHGHVLAADRAPWLAISPDPVIGERAYDLAWLALDRLETLIGSPGPKGAARRRITRLAEAVEVDPDRLRGWTLYRATATGLRHLGADQDRLGELYLEFASWL
>NZ_CP025394.1|WP_104816168.1|2887549_2888134_-|GNAT-family-N-acetyltransferase
MEQLTEVTIEAIDLAAWAPYALDVQAIAFGLTPEEVAVRLQIVGRHALQPGVRALGALSEGRLVGFGYGMPNQREHWWSTVIQPHLEAQGHGDWLDDVFAVTELHVLPEYQGRGLGTRLIRSLCEGSGQPRSILSAIDAETPARRLYRSLGYRDLARPVRFPNTVRPYAVMGARLPLLGAPSGAAPQSQDANSR
>NZ_CP025394.1|WP_104816169.1|2888268_2889144_-|GNAT-family-N-acetyltransferase
MLPGPFQVARALATTRVLDAADLVDTLEVLHRDPVANAFVATRVEAVGLDPWRLGGEMWGWFDADGRLESLCYAGANLVLVGAGPEAVRAFAERARRQGRRCSSIVGPAEPTAALWALLERSWGPAREVRAHQPLMATSSRSTEVAPDPLVRRVRRGEVEAVMPACVAMFTEEVGISPLAGDGGLLYQARVAELVGAGRSFARFDEAGQVVFKAEIGAVTAGACQIQGVWVAPEHRGQRISEGGMAAVLDFALADVAPVASLYVNDFNVRARAAYRRVGFHEVGAFMSVLF
>NZ_CP025394.1|WP_104816170.1|2889268_2890429_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MTAISLGIPSLPLKPLATRRVSRQIKVGNVLVGGDAPVSVQSMTTTVTADINATLQQIAQLTASGCQIVRVAVPTQDDADALPVIAKKSGIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIKQFDDKVGEIAKAAKDAGVPIRIGVNAGSLDKRLLEKYGRATPEALVESALWECSLFEEHDFRDIKISVKHNDPVVMINAYRQLAAACDYPLHLGVTEAGPAFQGTIKSAVAFGALLAEGIGDTIRVSLSAPPAEEIKVGIQILESLNLRQRGLEIVSCPSCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIEEALKLAEAMQAEGVESGEPTVIAAG
>NZ_CP025394.1|WP_104816171.1|2890573_2891881_-|site-2-protease-family-protein
MAMVMWVLGILLFLVGLLFSIAWHELGHLSTAKLFGIRVPQYMVGFGKTIWSRKKGDTEYGIKAIPLGGYIRMIGMFPPGADGRITKRSSSPWRSMIEDAREASYEELQPGDEHRLFYTRKPWKRVIVMFAGPFMNLVLSVALYLAWFMGIGYQTTVPTVSTVSQCVVPAATARTDVCPADAPKSPANAAGLRAGDRIVSFDGDAISTYTQLQADIRKSPGKQVTIVIERGGQQQSLTAGITSNTVAAVDKDGRPIDGKTVTAGFLGFSPAIGVRHLSLGESATQMTDMAKHGITSLAALPGKIPGLWHAIVGHDPRPADSPMGMVGAARLGGDVFAMDLPATQQLAFMVQLLAGINLSLFLFNMLPLLPLDGGHIAGALWESLRRHAAKLFRRSDPGPFDVAKLMPLAYVVAGIFICFTALVMVADIVNPVKIN
>NZ_CP025394.1|WP_104820824.1|2891917_2893147_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MNELAHPHTRFTPKVADPSGPRELVILGSTGSIGTQAIDVVLRNPDRFKVVALSAAGGRVELLAEQALALGVHTVAVADEAALPALREALVAKAGGRALPTLLAGPEAATELAGLECHSVLNGITGSIGLGPTLAALRAGRVLVLANKESLIVGGPLVKAVARPGQIVPVDSEHAALFQALAGGTRAEVRKLVVTASGGPFRGRTKSELAAVTVEDALAHPTWAMGPVVTVNSATLVNKGLEVIEAHLLYDIPFDRIEVVVHPQSVVHSMVEFTDGSTLAQASPPDMRMPIALGLGWPERVPDAAPGCDWTKAATWEFFPLDEEAFPAVALAREVGTLGGTAPAVFNAANEECVDAFLKGRLAFTAIVDTVAKVVAEHGAPASGTSLTVEDVLHAEGWARARARQLAAG

Crispr_ID: NZ_CP025394_9

• CRISPR_ID: NZ_CP025394_9
• CRISPR_location: 3015872-3015970
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_9

Consensus_repeat	Method
CGCGCCGGTGATGCCCAGGTCGTC	CRISPRCasFinder

spacers of NZ_CP025394_9

>9.1|3015896|51|NZ_CP025394|CRISPRCasFinder
GAGGAGCAGGTCCTCGAGGTCCTGGTCGAGCCGGTCCAGGTCGCGCGGGAC

CRISPR arrays and Neighbor proteins around NZ_CP025394_9

CRISPR arrays

The CRISPR arrays of NZ_CP025394_9

>merge|NZ_CP025394|9|3015872-3015970|CRISPRCasFinder
CGCGCCGGTGATGCCCAGGTCGTCGAGGAGCAGGTCCTCGAGGTCCTGGTCGAGCCGGTCCAGGTCGCGCGGGACCCGGCCGGTGATGCCCAGGTCGTC

>NZ_CP025394|9|8|3015872-3015970|CRISPRCasFinder
CGCGCCGGTGATGCCCAGGTCGTC	GAGGAGCAGGTCCTCGAGGTCCTGGTCGAGCCGGTCCAGGTCGCGCGGGAC
CCGGCCGGTGATGCCCAGGTCGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104816239.1|3011351_3012020_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP025394.1|WP_104816237.1|3009817_3010600_+|hypothetical-protein	unknown	unknown	gnl|CDD|226951
NZ_CP025394.1|WP_104816243.1|3017186_3017918_-|DUF998-domain-containing-protein	unknown	unknown	gnl|CDD|377627
NZ_CP025394.1|WP_104816234.1|3005267_3006623_-|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NZ_CP025394.1|WP_104816248.1|3025758_3026103_-|chorismate-mutase	unknown	unknown	gnl|CDD|181719
NZ_CP025394.1|WP_104816246.1|3024035_3024995_-|signal-peptidase-I	unknown	unknown	gnl|CDD|274044
NZ_CP025394.1|WP_104816232.1|3003179_3003551_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104816250.1|3029526_3030726_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274646
NZ_CP025394.1|WP_104816244.1|3020643_3022839_+|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NZ_CP025394.1|WP_104816241.1|3013367_3015692_-|TOMM-precursor-leader-peptide-binding-protein	unknown	unknown	gnl|CDD|376866
NZ_CP025394.1|WP_104816245.1|3022939_3023977_+|EamA-family-transporter	unknown	unknown	gnl|CDD|273359
NZ_CP025394.1|WP_158702608.1|3006944_3008327_-|nitroreductase-family-protein	unknown	unknown	gnl|CDD|188352
NZ_CP025394.1|WP_104816238.1|3010618_3011224_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP025394.1|WP_104816233.1|3003604_3005023_+|NarK-family-nitrate/nitrite-MFS-transporter	unknown	unknown	gnl|CDD|184994
NZ_CP025394.1|WP_104816249.1|3026400_3026826_+|OsmC-family-protein	unknown	unknown	gnl|CDD|274650
NZ_CP025394.1|WP_104820841.1|3027281_3029408_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NZ_CP025394.1|WP_104816240.1|3012019_3013246_-|hypothetical-protein	unknown	unknown	gnl|CDD|226951
NZ_CP025394.1|WP_104820840.1|3016338_3017160_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP025394.1|WP_104816247.1|3025125_3025476_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104816235.1|3006603_3006948_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104816239.1|3011351_3012020_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.74307e-57
NZ_CP025394.1|WP_104816237.1|3009817_3010600_+|hypothetical-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	4.88974e-11
NZ_CP025394.1|WP_104816234.1|3005267_3006623_-|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	4.55675e-07
NZ_CP025394.1|WP_104816248.1|3025758_3026103_-|chorismate-mutase	gnl|CDD|181719	PRK09239, PRK09239, chorismate mutase; Provisional.	2.45105e-46
NZ_CP025394.1|WP_104816246.1|3024035_3024995_-|signal-peptidase-I	gnl|CDD|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	6.05953e-39
NZ_CP025394.1|WP_104816250.1|3029526_3030726_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	2.65643e-167
NZ_CP025394.1|WP_104816244.1|3020643_3022839_+|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	1.08095e-148
NZ_CP025394.1|WP_104816241.1|3013367_3015692_-|TOMM-precursor-leader-peptide-binding-protein	gnl|CDD|376866	pfam02624, YcaO, YcaO cyclodehydratase, ATP-ad Mg2+-binding. YcaO is an ATP- an Mg2+-binding protein involved in the peptidic biosynthesis of azoline. There three motifs involved in the binding are, in UniProtKB:P75838, 71-79: Sx3ExxER, 184-203: Sx6Ex3Qx3ExxER, and 286-290: RxxxE. Three slightly different functional families are represented in this family, proteins involved in TOMM (thiazole/oxazole-modified microcin) biogenesis, non-TOMM proteins such as UniProtKB:P75838, and TfuA-associated non-TOMM proteins involved in trifolitoxin biosynthesis. UniProtKB:P75838 hydrolyzes ATP to AMP and pyrophosphate.	3.19437e-106
NZ_CP025394.1|WP_104816245.1|3022939_3023977_+|EamA-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	8.21591e-22
NZ_CP025394.1|WP_158702608.1|3006944_3008327_-|nitroreductase-family-protein	gnl|CDD|188352	TIGR03605, antibiot_sagB, SagB-type dehydrogenase domain. SagB of Sterptococcus pyogenes participates in the maturation of streptolysin S from a ribosomally produced precursor polypeptide. Chemically similar systems operate on highly diverse sets of bacteriocin precursors in numerous other bacteria. This model describes a domain within SgaB and homologous regions from other proteins, many of which appear to be involved in biosynthesis of secondary metabolites. While some substrates may be intermediates in non-ribosomal peptide syntheses, others are involved in heterocycle-containing bacteriocin biosynthesis, and can be found near SgaC-like (see TIGR03603, cyclodehydratase) and SgaD-like (see TIGR03604, "docking") proteins. Members of this domain family are heterogeneous in length, as many have a partial second copy of the domain represented here. The incomplete second domain scores below the cutoffs to this model in most cases.	2.92299e-15
NZ_CP025394.1|WP_104816238.1|3010618_3011224_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.9353e-55
NZ_CP025394.1|WP_104816233.1|3003604_3005023_+|NarK-family-nitrate/nitrite-MFS-transporter	gnl|CDD|184994	PRK15034, PRK15034, nitrate/nitrite transport protein NarU; Provisional.	2.53126e-134
NZ_CP025394.1|WP_104816249.1|3026400_3026826_+|OsmC-family-protein	gnl|CDD|274650	TIGR03562, osmo_induc_OsmC, peroxiredoxin, OsmC subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein OsmC, or osmotically induced protein C. The member from Thermus thermophilus was shown to have hydroperoxide peroxidase activity. In many species, this protein is induced by stress and helps resist oxidative stress. [Cellular processes, Detoxification].	3.72522e-63
NZ_CP025394.1|WP_104820841.1|3027281_3029408_+|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.23816e-102
NZ_CP025394.1|WP_104816243.1|3017186_3017918_-|DUF998-domain-containing-protein	gnl|CDD|377627	pfam06197, DUF998, Protein of unknown function (DUF998). Family of conserved archaeal proteins.	7.73714e-07
NZ_CP025394.1|WP_104820840.1|3016338_3017160_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.05775e-14
NZ_CP025394.1|WP_104816240.1|3012019_3013246_-|hypothetical-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.77934e-35

Protein sequences

>NZ_CP025394.1|WP_104816241.1|3013367_3015692_-|TOMM-precursor-leader-peptide-binding-protein
MTAVGAGAAGEARLGFKAHLRVRVVPGEATYLVSPRSVTALRGPEVEILAPFLDGTRTGVEILAAVAGRLSADQAIKGLRALVETGLVRTRTDTVDPAAEAYWDLAGLNGGQAAADLARDGIRVVTLGGIDQEAVEQACRDSGLRLVQGRSAALTLMLCNDYLDPALAEIDARQRAARRPWLLARPTGPDPWIGPIFRPGESACWHCLANRLRGHRRSELPLLHADLRQPPVAPASPPGAGGAPLPRAEASLAAGRAIGVQTAVLEAAKWLSGLRYEGQDAVYALDTLTLAGSSHPVTRRPQCTECGDGALVARLVRRPVVLTSRPKAPGAANGHRALTPGQMLAAYGHLVDPITGVVRELRRDPRSPEFAHSYLSGHNLALAPGTLGGLRSGLRSLSGGKGLTDEEARVSALCEAVERYSGSWHGDEPVVRASYRELGKSAVHPARIQLFHDRQHSGRAQWNAEHADSSFQQVPEPFDEQRVVDWTPVWSLTAGERRLVPSSLLYYSATAPDEGLPVADSNGNAAGASLEDAVLQGFLELVERDAVALWWYNRTRQPAVDLDAFAATESWLPAMRAGHRGMGREVWVLDLTADLGIPVMAALSRRTDQPAEDVIFGFGAHLDPAVALRRALTELNQLLPAVADATARDGGYAVQDRTAVAWWRTATVARQPYLRSDEGVPARGPEAWECRRTTDLKDDVEGAIQLLSRHGLELLVLDQTRPDIGLPVVRVIVPGLRHFWARFAPGRLYDVPLALGRVKSATPFEELNPIPLFV
>NZ_CP025394.1|WP_104816240.1|3012019_3013246_-|hypothetical-protein
MRDGQPAQPPQRLADTAEVLAPKLARGMLYAVLVAYLVITYLNILTFIRDIPTIIAGMVGVLVIFMLQLLHSNPRMRQATVRVKTLSLGSQALLTFLPLIVFHRGWGGMGSFLAGSFLLILPARWAWTLYGLTGLSMMVYGGIAGMSVVDTVYMGQSTWLSGLVVYGISRLAELVTVLHETRGELARMAVSNERLRFARDLHDLLGYSLSAISLKSELIRRLLPASPDRAREEVSEVLDISRQALADVRLVASGYREMSLVQECASAREVLRAAEVDAALTVSVGELPPAVDTVLATVLREGMTNLLRHSRVRSCTIEAVQEDNTVQLSVVNDGVDPGVATVDPHGGSGLGNLTLRVRAMGGTLSAGLRPDGRFHLVATVPVEAAPEAVGLDIQPLRALRRLSRKVAV
>NZ_CP025394.1|WP_104816239.1|3011351_3012020_-|response-regulator-transcription-factor
MVRPGSAVPETAAAPEAEGRKLRVLLAEDAHMVRGALIALLQLEPDIEVVVDVDRGDAILPAALEHRPDVAVLDVDLPGMDGLAAAAQLAEQLPSCRALMLTSLGRPGTLRRALDAQVSGYLLKDALPEQLAAAVRSVAAGQRVIDPQLAMSVWESRESPLTAREGEVLQLASPGAEVGEIARALHLSEGTVRNYLTSIVVKVGGRNRIDAIRIAREAGWIS
>NZ_CP025394.1|WP_104816238.1|3010618_3011224_+|response-regulator-transcription-factor
MITVVLADDQRIIADALGQLLAQEDDIEVLAVVGDGDQALAAIRQHRPAVALLDIDMPKQDGLTVTAQVKQELPQIKVVILTSFGQPGYLTRALNAQADGFLAKNSQVEEIIDTVRQVAAGRRVIDPALAVTALTAAPNPLTGREREVLEAAEHGAPLSDVASRLHLAHGTIRNHLSAAMAKTGTRTRVEAAKAARERGWL
>NZ_CP025394.1|WP_104816237.1|3009817_3010600_+|hypothetical-protein
MARYALWPFRPAPSAALAGAAASGVTAGGVTAGGVSTATSPSLAGKLDQTDRRLSALSTRLREVQAAGEHAQLFSLEHELRAALHEVRFTAPGYRPVSLSAALVRAADTLRAVGIELDIAAALETASAWVAGAPGWSPQACDALGWVLRECTANILRHSTAHRAWISLSPTADGLRLAIGNNGVPRRRGGPERSGFGEERSGSRHRPLGPGSGSGIPSMLAQVSVMGGTLRVDRSDSRFELVAVVPTTPRSGVRATAGSV
>NZ_CP025394.1|WP_158702608.1|3006944_3008327_-|nitroreductase-family-protein
MLANRLGVSVADESFLTWLAGLTLSGSLTSFDQPIGPALPGVRTARATGEFLKAVKVHRESLGESLGARPHRSAPEHTAHAHAEGEPAGPAVSGPTISGPALDRPLVDGPARAGHPQDRADTARRAADIAHGAAGTAHRSAGTAHRAADTAHRQTDSAFPPRPVHRPADPARRPVFDHTVFEWPVFDHPVVAGRRSYAPVPPAAGESDHTYAAGEHFTPVPLHAVPRPAHRSAPPRLRPVPLPAVDVALMGAPALPELLALLGGAGQGGPGGEADGEPGVCTGELDPARLATLLGLAAGAVSGPAAPGPERSGVGATTHPLLLDVVVRRVSGIPAGSYRYLPGEHLLSPRPAVDTAALLSTAPYAAPRPAWHRPTAAEQAPVLLMLGTETGVSTLRYGPRGARSALLEAGRLTQSLLLTAAALELRAVTVCGGYDELALASGGGGRPTQPLCLVALGAAA
>NZ_CP025394.1|WP_104816235.1|3006603_3006948_-|hypothetical-protein
MITIRPTARPTATVVVPNPDLRALLVERAAGHCFVDRERRAEARHAVVERAGWLLAGDVALVEEAAPVPTGALPHHAAVVAGLLRRLTGAPGEWYAFDLDGLSLRGGHGVPDLR
>NZ_CP025394.1|WP_104816234.1|3005267_3006623_-|hypothetical-protein
MSLISADHLTAAGAATTTAPAATPVKPAPAQPAVTKPAVTKSAVSKPTVSKPTAQPSAARSAAKPGGAAPGSAKPAAPGASGTKTISTTGGAARCDTTPPAALRAVSGPHRTRFAEPSQARPAQPGSAERPGSGAPSATVPPRLTPSVPAPRWPSVLPLPPEEEAEPAAEEFSPAVQGRPSAGLGVQYDSSGSVVVGGPRTWRFSGEAGTRLGEILLGQREAEAAEAELLHTLGLWETADPELAAAQRTAFVDTDVTAGALRFCGRWAPTTRRHGSGAESLAAWRQLRPVVVGDSPLARALVRELALGWPATEEGAEQLLVLVDGAAPPVADRSEGLEAENGAAGRAAGRAVGARLPVLSWGGTVSIGPWTPEGELECVVCHADRRGRSACVAGAPGLASSTVDMDLLAALVVAELVHTGAGIGRGARPGLIVEHTPAAGRTKAYSCHHAD
>NZ_CP025394.1|WP_104816233.1|3003604_3005023_+|NarK-family-nitrate/nitrite-MFS-transporter
MSTTEEKAPDHRRENYGPGRTISTWEPEDPGFWAATGSKVANRNLWVSVPALLLAFVVWQVWSVTVVQLSKVGFTFSESQKFWLTAIPGLTGGTFRLVYTFVGPVVGQRRWTTFSTIILIGPLLWLGFAVQDTSTPYWVMVVIAALCGIGGANFASSMVNIGFFYPKARKGNANGINGGLGNLGVSVVQLVAPIVITAGILGPPAGGPQKQKDGTEVWLQNGAFLWIPLLVVMTLAAWFLMNDLKVAAAPFSRQKIIFQRKHNWLMTVLYVGTFGSFIGFASALPNLINNTFTPINSAYSATKYAWVGPFIGALTRWLGGWLGDKVGGARCTMISFVGMAASIIVVINALPSGGDNGNFWVFYAGFLCAFLFSGIGNGSTFRQIPVIFLNQHRTAAGPDPQAQEEARHQAEMEAGAVTGFSSAIAAYGFFFIPAMFALFPVTSSLWVFVAFYVVCLGVCWWFYARPGAEAPS
>NZ_CP025394.1|WP_104816232.1|3003179_3003551_+|hypothetical-protein
MTTPDPVHFPPDYHPGSDEPRLNRPLSDRYPQIRSTSGYGDPRIRHTGPGLGAGGEHEPERSAVLTARVLLVITIVIGQLWALTVATNAWMKGDTSTAWWCTGFSAASFLVVLLAWWISPRDR
>NZ_CP025394.1|WP_104820840.1|3016338_3017160_-|alpha/beta-hydrolase
MDGRALHVRAEGSGPVCVLSAGLGMAWFDWEPVVPLLAPHRTVVRFDRPGYGLSAPGRAAPTAAGEADRIARLLTALGLPGRCTVVGHSLAGFHAEAFARLYPDRTAGLVLVDASAEPCPRPRPAPAARDLAARAAAATAGALALPYLLGPPGRRLVAALSTVGRTAPAPAALVRRSYRPTRALRAALRENAGYLDVAAELAALRTHAPLPAVPVTVLAADRGRGTRAAARWLTRQRELADLLGAAFRVAAPAGHLVMYDRPDLVARAVLDGS
>NZ_CP025394.1|WP_104816243.1|3017186_3017918_-|DUF998-domain-containing-protein
MRRAAASPQSRVIAVLLSVSALAYTAWVLEVVIGTGLDPVQAYVSELAAEDQPLGGLFRATDLVAGAAVLVAAVLALVGLERRAWATTGWSALALFGAATVADSRLPLSCKPTLDPECAARETAGLVPATHTAHAVSSTLAMIGALAALTALTIAARRYGWWPRFARLGPWLLGAELLATGWSLAAIAAFQAGRGTWSLGAGQRLQVLLVAVSLAVLAPAVGSARGDAAARSPRSAGTVRSTR
>NZ_CP025394.1|WP_104816244.1|3020643_3022839_+|penicillin-binding-protein
MTLGGLVTAVLLGMTLFGLGIAFVQVPDAHAAAVAQSNTWLYRDGSVLARTGETDRQIVPIDRISPAAREAALAAEDRNFYHEGAVNLKGLARAAFTTATGGGTQGGSTITQQYVKNTYLTQKQTVTRKVQELFISLKVDATKSKDEILAGYLNTSYYGRGAYGIQAAAQAYFGVDAARLDAAQGAYLAALLNAPSAYDVSTATAAGRQNALDRWNHVLDAMVKEGWLPAGDRAAAAFPQVREPQSPPGLSGQAGYLVRAATDYLTSHGIVNEAALAQGGYTVRLTVDPQREQQLETAVKAQLTDRLDPAQRRKDADAQAGAVSVDPSTGEVLALYGGTDATKHWIDNATRRDYQAGSTFKAIALAAALDSGAKTQGGQRITPSTVYDGTSGRPVRGGTGTPYAPPNEGGRSYGPVTLRQATDWSVNSAFAQLAQDTGLEKVRQTAVDLGLPASTPGLTADPAIPLGVSTPSVLDLAGVYATLDHGGRRIEPRLVAEVRHGGEGLRLPQPATTRAVSERTAAEVTDLLRGVVDDPGGTGYRAKELGRPSAGKTGTTDDSRSVWYAGYTPELVTVVGLFGQDPKTGAQVTLDDVGGTGSAAGGRYPAQIWTAYMKAALDGQPVTPFPKAPADPAASSPSPTADPSATGATPSRGPSPSSSATASSPAGTGTGRPATPPAPSATPTGDRPTPTPTPSSSPSSSPPPPPSPSPSPSGSPSPGPSPSGDPDRARG
>NZ_CP025394.1|WP_104816245.1|3022939_3023977_+|EamA-family-transporter
MHSSPSRPRGQVRALGLPLALVSAFAFGGSGTAAKPLIEAGLSPLHVVWLRVTGAAVVLLPLAYRHRAVVKQRPWLLLGFGLLAVAGVQACYFAAISRIPVGVALLLEYFGPLLLLGYIKFVQRRPITRAAAIGTGVAVAGLACVVEVWHGLNFDPLGVLFGLGAACCQVGYFVLADAGREGEHPVDPLALSAYGLLTGAVVLTVLTRPWEADWGLLAGRAVMNGHSLPALIPAAWMVLIATVLAYLTGVVSVRHLSPQVAAVVANLEAVVAAVSAWFLLGEHLGTAQVIGGFLVLLGAFAAQTSKPAATTADAASATGGVGTASVAEDGGALDAVAGSGSARRD
>NZ_CP025394.1|WP_104816246.1|3024035_3024995_-|signal-peptidase-I
MGYERVGHELVGQGRAAQGSADQERQDRQDRPGQQDPPDGGWVGPTGTAPGAHHGGAARQEYESAPSEQAGRAEPGHVQGGHGEPGAARRSVRGFWRARAARRSGQGGRRRWPWWAEFPVMVTAGLAAALLIKTCLFQVFTIPSGSMENTLRIGDRVAVNKLAPLFGWEPKAGEPVVFKDPGGWLPPQAGGSSGPVGEALSFIGLLPPSGDNYLVKRVIATGGETVQCNAKTLRVDGHPVAEPYLHVGDDSCAGLDFGPVKVPQGYVWVEGDHRSDSADSRYHREGPAGGAVPVTDVVGPVSAVVWPLNHLDWFGATGR
>NZ_CP025394.1|WP_104816247.1|3025125_3025476_-|hypothetical-protein
MARKQQRSSTRQNGRVTGGRTGGPRRAGGAVLGAAAVAAGAAGLAGFAGHSPVAEVSAGVSRLAAVGESVPFAVADWDAAGTGAALAALAGGVGSVVVIRRRQPARDAVRSGSQAA
>NZ_CP025394.1|WP_104816248.1|3025758_3026103_-|chorismate-mutase
MTDQPTNSAAAAHTSLDEVAPDVRDELRCLRESIDNFDAAVVHLLAERFKATQRVGKLKAEHKLPPADPERERDQIRRLRELAAGAHLDPVFAEKFLNFIIAEVIRHHEAMARS
>NZ_CP025394.1|WP_104816249.1|3026400_3026826_+|OsmC-family-protein
MATTRTARTAWEGNLVDGNGLVTFASSGIGEYPVSWPSRAEAANGKTSPEELIAAAHSACFSMALSHGLAGAGTPPTKLDTQADVTFQPGTGITGIHLTVTGQVPGLDEAGFVKAAEDAKANCPVSQALTGTTITLTAQLA
>NZ_CP025394.1|WP_104820841.1|3027281_3029408_+|EAL-domain-containing-protein
MDGSADSPADSSADGHEREPAEPGTVGGREHHAHPTLDRHPATEPLGRSAAGATEAATTAEPAAPAGPARQHPGHPGPVPGAFTGLSDLPDSVCPLCSAPTESGTEQLLAALRASESRFRAAFADAGIGMLLVGPDDLIIEANPAFAAMIGHEVPDLVRTHIHEIIDPEDTPRRLYRELVRGERDRIRVEKRLKHREGREIWSNVTISLIRDGSGRPLYTLAMVEDVTEQRMLGDRLAYQAIHDPLTRLPNRALFFEQLNAAFARTADESSIPPGAATPGTLPTTNGDSSNPRRVGLCYVDLDGFAAINETLGHHVGDQLLVAVAARLERGFARGEGRLVARLGGDEFAVLVPDSDGHDQLTSLAAELIKALEQPFDIAGQQLVVTASIGVVERPVLDTTPTDLLKDADATLYWSKADGRARWTLYDPDRGAHQLTRQRLATALRPALERGEFTVEYQPLVGLADGAVHGAEALVRWRHPRYGTLSPDRFIPLAEESGAIVPLGKWVLEESCRQAQRWLTESPAAEAFVSVNLAARQIWDSDVVADVAEVLERTGLPPRLLQLELTESAVLGPGGRPVQALQALADMGIRIAIDDFGTGYSNLAYLSRLPVHVLKLDGSFVEGFRDPVPGGRPDGRFRRADADEQIVGAMVQLAHALGLTVTAEGIENAAQAERLRQTGCDTAQGWYFARPGPAEAVAAMLRNHHNPA
>NZ_CP025394.1|WP_104816250.1|3029526_3030726_-|LLM-class-flavin-dependent-oxidoreductase
MSTSDAPQRADQGPEGSGATPATGPASAATPGPASADTADSGSVHASSALVVDPIRGVARGTAPAPLSILDLATIGAGYTPAQALAATTALAQSAERWGYHRFWVAEHHGMPGVASSNPAVLIAHLGANTTTLRLGSGGVMLPNHAPLVIAEQFGLLEALNPGRIDLGLGRAPGTDQATARALRRGRTDGAEDFPEQLSELTHFLDGSFPANHPYARLTAVPKGEGRPPIWLLGSSGFSAQLAGRLGLPFAFAHHFSAANTEPALELYRSSFRPSAVLDTPYALIGVGAVATEEEKQAHRHARTAALGMLRLRLGTPGPIPTLAEAEAYPYNAAEADFVESWIGNLVLGTPGEVADGLEALRNRTGADELMVTSHVHGHEVRHRSYGLIAEAYGLTAAS

Crispr_ID: NZ_CP025394_10

• CRISPR_ID: NZ_CP025394_10
• CRISPR_location: 4584278-4584376
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_10

Consensus_repeat	Method
ATTCAGGGGCGCGGGGAACTGCGCG	CRISPRCasFinder

spacers of NZ_CP025394_10

>10.1|4584303|49|NZ_CP025394|CRISPRCasFinder
ATCTCGGAAGAAGCCGACCGGATTCTCGCCGCAGAGGACCAGTTGCACT

CRISPR arrays and Neighbor proteins around NZ_CP025394_10

CRISPR arrays

The CRISPR arrays of NZ_CP025394_10

>merge|NZ_CP025394|10|4584278-4584376|CRISPRCasFinder
ATTCAGGGGCGCGGGGAACTGCGCGATCTCGGAAGAAGCCGACCGGATTCTCGCCGCAGAGGACCAGTTGCACTATCCAGGGGCGCGGGGAACTGCGCG

>NZ_CP025394|10|9|4584278-4584376|CRISPRCasFinder
ATTCAGGGGCGCGGGGAACTGCGCG	ATCTCGGAAGAAGCCGACCGGATTCTCGCCGCAGAGGACCAGTTGCACT
ATCCAGGGGCGCGGGGAACTGCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104817429.1|4597781_4598081_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_168219616.1|4588009_4588852_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|223635
NZ_CP025394.1|WP_104817423.1|4588923_4589853_-|hypothetical-protein	unknown	unknown	gnl|CDD|273649
NZ_CP025394.1|WP_104817412.1|4572562_4573966_+|biotin/lipoyl-binding-protein	unknown	unknown	gnl|CDD|273776
NZ_CP025394.1|WP_104817418.1|4580094_4581636_+|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl|CDD|376587
NZ_CP025394.1|WP_104817421.1|4586234_4588007_+|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|226951
NZ_CP025394.1|WP_104817427.1|4594926_4595196_+|RNA-binding-protein	unknown	unknown	gnl|CDD|273232
NZ_CP025394.1|WP_104817413.1|4573980_4574769_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_CP025394.1|WP_158702265.1|4595561_4595708_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104820995.1|4576751_4577414_+|hypothetical-protein	unknown	unknown	gnl|CDD|234704
NZ_CP025394.1|WP_104817416.1|4577598_4578366_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_CP025394.1|WP_104817426.1|4591165_4594930_+|RHS-repeat-protein	unknown	unknown	gnl|CDD|225750
NZ_CP025394.1|WP_104817417.1|4578367_4579864_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP025394.1|WP_104817419.1|4581648_4582662_+|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl|CDD|376764
NZ_CP025394.1|WP_104817424.1|4589929_4590328_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_158702263.1|4575980_4576610_+|hypothetical-protein	unknown	unknown	gnl|CDD|240291
NZ_CP025394.1|WP_104817414.1|4574765_4575968_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|182528
NZ_CP025394.1|WP_104817428.1|4596819_4597707_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274648
NZ_CP025394.1|WP_158702264.1|4590427_4591009_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_158702262.1|4572181_4572418_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_168219616.1|4588009_4588852_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.10713e-62
NZ_CP025394.1|WP_104817423.1|4588923_4589853_-|hypothetical-protein	gnl|CDD|273649	TIGR01480, unnamed_protein_product, copper-resistance protein, CopA family. This model represents the CopA copper resistance protein family. CopA is related to laccase (benzenediol:oxygen oxidoreductase) and L-ascorbate oxidase, both copper-containing enzymes. Most members have a typical TAT (twin-arginine translocation) signal sequence with an Arg-Arg pair. Twin-arginine translocation is observed for a large number of periplasmic proteins that cross the inner membrane with metal-containing cofactors already bound. The combination of copper-binding sites and TAT translocation motif suggests a mechansism of resistance by packaging and export. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0.00527096
NZ_CP025394.1|WP_104817412.1|4572562_4573966_+|biotin/lipoyl-binding-protein	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	2.64533e-30
NZ_CP025394.1|WP_104817418.1|4580094_4581636_+|cytochrome-ubiquinol-oxidase-subunit-I	gnl|CDD|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_CP025394.1|WP_104817421.1|4586234_4588007_+|GAF-domain-containing-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.22464e-24
NZ_CP025394.1|WP_104817427.1|4594926_4595196_+|RNA-binding-protein	gnl|CDD|273232	TIGR00717, 30S_ribosomal_protein_S1, ribosomal protein S1. This model describes ribosomal protein S1, RpsA. This protein is found in most bacterial genomes in a single copy, but is not present in the Mycoplasmas. It is heterogeneous with respect to the number of repeats of the S1 RNA binding domain described by pfam00575: six repeats in E. coli and most other bacteria, four in Bacillus subtilis and some other species. rpsA is an essential gene in E. coli but not in B. subtilis. It is associated with the cytidylate kinase gene cmk in many species, and fused to it in Treponema pallidum. RpsA is proposed (Medline:97323001) to assist in mRNA degradation. This model provides trusted hits to most long form (6 repeat) examples of RpsA. Among homologs with only four repeats are some to which other (perhaps secondary) functions have been assigned. [Protein synthesis, Ribosomal proteins: synthesis and modification].	4.99143e-05
NZ_CP025394.1|WP_104817413.1|4573980_4574769_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.5469e-107
NZ_CP025394.1|WP_104820995.1|4576751_4577414_+|hypothetical-protein	gnl|CDD|234704	PRK00259, PRK00259, intracellular septation protein A; Reviewed.	0.00108281
NZ_CP025394.1|WP_104817416.1|4577598_4578366_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.09864e-92
NZ_CP025394.1|WP_104817426.1|4591165_4594930_+|RHS-repeat-protein	gnl|CDD|225750	COG3209, RhsA, Rhs family protein [Cell envelope biogenesis, outer membrane].	1.66641e-37
NZ_CP025394.1|WP_104817417.1|4578367_4579864_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.06914e-61
NZ_CP025394.1|WP_104817419.1|4581648_4582662_+|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl|CDD|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	3.587e-113
NZ_CP025394.1|WP_158702263.1|4575980_4576610_+|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.000736331
NZ_CP025394.1|WP_104817428.1|4596819_4597707_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274648	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes one such subfamily, exemplified by Rv1855c from Mycobacterium tuberculosis. [Unknown function, Enzymes of unknown specificity].	2.15529e-41
NZ_CP025394.1|WP_104817414.1|4574765_4575968_+|ABC-transporter-permease	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	4.13907e-64

Protein sequences

>NZ_CP025394.1|WP_104817419.1|4581648_4582662_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MQLHDLWFVLIAVLWIGYFFLEGFDFGIGVLTKLLARDTAERRVLINTIGPVWDGNEVWLLTAGGATFAAFPDWYATLFSGFYLPLLIILVCLIVRGVAFEYRAKRDGARWQRNWEEAIFWTSLLPAFLWGVAFANIVHGVDIDAQKNYVGSFWDLLNPYAILGGLVTLALFTFHGAVFASLKTNGDIRLRARTVARQLGLVTAVLALVFLSWTQAHQGDGWSLAAMIVAVLALVGALVANQLGREGWSFGLSGLTIAAAVAMLFLALFPDVMPSTLNEDWSLTAANAASSPYTLKLMTIVAAVFTPIVLLYQGWTYWVFRRRIGVQNIPATPTQAH
>NZ_CP025394.1|WP_104817418.1|4580094_4581636_+|cytochrome-ubiquinol-oxidase-subunit-I
MELAVAHETIARWQFGITTVYHFLFVPLTISLAAIVAGLETAWVRTGKEKYFHATKFWGKLFLINIAMGVVTGIVQEFQFGMNWSDYSRFVGDVFGAPLAMEALIAFFFESTFIGLWIFGWDRLPKKIHCACIWMVAIGTVLSAYFILAANSWMQHPVGYSIDPATKKAQLTDIGAVLFQNTTLVQVFHTLTASFLTGAAFMVGIASLHLWRAKRHGEPDRKKTASMLTSLRVGLAIAGIAGLGVAISGDTLGKVMFEQQPMKMAAAEALWDTSSPAPFSIFAVGDVNKGHNSVELEIPGILSFLAHSDFSSAVPGINDTAAAEAAKYGGQPTDYIPSIFVTYWGFRLMIGFGMTSFVAALVGLWTTRRKFWLAPEHRAGEDGIPKLMLTKNREMSIFFTKWSWRIGILTMGFPLIANSFGWIFTEMGRQPWAVFGLMKTSSAVSPNVGITTQVIALTTFTTLYAILAVIEVRLLAKYANAGPNTAEQPPAKDPTLRGPSSDEDADKPLAFAY
>NZ_CP025394.1|WP_104817417.1|4578367_4579864_+|HAMP-domain-containing-histidine-kinase
MRRHLLSRLSPARLSLRARLLVLALALVTIGLGVSDVVVLGTVRSQLVDQADGQLKRFAVQLGRRAPGASRTPGQGPNVRRLGQMLPSQYLVDYLDVDGRVQQTLRQPAEADPGPDLDELSPAQLVAKVGAGFTLPNERHDGHWRVVVLPLQRSDFSVSGVPSYLLAAVSLDDVDSTVAELSNAFLVIGGVVLVLIAGLGFFAVRAGLRPLARIGQDAELIAAGRLSHRMPELAPRTEVGRLSASLNEMLTQIEAAFAARAESEARMRRFVADASHELRTPLAGIRGFAELYRMGALAGPTEVQRTMQRIESEAVRMGGLVEDLLTLARLDEERPLDLAPMDLRTLAADALHDLTALDPGRPVALTGPLGSGAPQAAPVLGDEARLRQVVTNLVGNAVKHTPPGTAVRIGVGAGPGGCLLEVADSGPGLTPDQAARVFDRFYRVDPSRSRHEGGGAGLGLAIAAALAHAHGGSLTLDSTPGQGAAFRLLIPKARRPLS
>NZ_CP025394.1|WP_104817416.1|4577598_4578366_+|response-regulator-transcription-factor
MLSGGPQAAGGAASGASGGEAYLLVVDDEPNIRELLAASLRFSGFRVASAATGEEALASVAAERPDLVVLDVMLPDLDGFTVVERLREQTQWPQAAEHVPVLLLTAKDGTGDKVQGLAAGADDYVTKPFSLEELIARIRAILRRAGGPAEDGRLVVADLTLDPLAHEVTRAEKPVALSPTEFKLLHYLMANVGRVVSKAQILDHVWAYDFGGDLSIVESYISYLRRKLDSGPAHGPKLIHTVRGIGYALRRPPQG
>NZ_CP025394.1|WP_104820995.1|4576751_4577414_+|hypothetical-protein
MPARRSGGSAALGWALTIVCNVIAPVVTYGQLTDHGYGEFTALLASAVWPVIDLLIYLAWHRKVDEFAVISLVFLVLTIVVSLAGPHDAHLLLVKDSFVTGLFGVVCLATLAAPRPLMFYFGRKFATDGTKEGAERWNALWQYPTFRAVQRNLTLGWGLAYLAEAALRIALSYTLSTSAMVTLNSVLSYGVTGLLVLWTVLYAKRARAKGAAATAAAAAA
>NZ_CP025394.1|WP_158702263.1|4575980_4576610_+|hypothetical-protein
MSAEHDPKKLELLATAPDARDITAELAAPPRRKLPWLTLALAGAVLVTVSFAGGVWYEQGNGKGSTTTRAAGQGRQGFGGGGQGGYGQGGTRRQGGGTGGGQGGGFTRGTVKSVDGTTVYLTDANGNTVKVTTGDQTKVQLNKEGKVTDLQPGQSVTVIGTPDSSGGYSATQLMEGASGGFGGGFGGGRGGGGTGGNGGGGNGGGAPQG
>NZ_CP025394.1|WP_104817414.1|4574765_4575968_+|ABC-transporter-permease
MILWQMLRFALGGLAANKVRSALTMLGVLIGVASVILLLAVGNGSSTAVKNSITSLGTNSLTVSSSSLRGTGGVAKKLTVADAKALATDTQGNAIKSVAPVVTTSATALYGNISYTPGQVVGTYPAYFETANQKVAKGDYFSNDDVLNSRKVAVIGSTTASQLFDTEDPVGRKIVLGGTPFTVVGVLQTKGSTGFNDPDDVVIAPLPTVQNAFTGFGSVNQILVQATSADTTTAAQSDITRVLMGTHAIADPTKLDFRVSNQASLLTARESTTKTFTVLLGAVAAISLLVGGIGITNIMLVTVTERTREIGIRKALGAPKGVILGQFLTESTLLSVIGAGLGVLAGIAGSHFSIVGIKPVVIPESVLGAFAIAVAIGLFFGSYPANRAASLRPIEALRHE
>NZ_CP025394.1|WP_104817413.1|4573980_4574769_+|ABC-transporter-ATP-binding-protein
MSQKQPPVIQIRQVTKAYGHGDATVHALRGPADPATGAPLGVSLDIEQGDFVAVMGSSGSGKSTLMNILGCLDVPTAGRYLLDGIDVGHLDEGQLSLVRNRKIGFIFQSFNLVPRTTALAQVELPLAYAGVRAAERRERALAALDLVGLADRAGHKPNELSGGQQQRVAVARALVTAPAMLLADEPTGNLDSRSTEEVLSIIDRLNATGRTVVLITHEDEVARHAKRVIRLVDGAIVQDLRQAPVQGPPPALRAHDLDGVRT
>NZ_CP025394.1|WP_104817412.1|4572562_4573966_+|biotin/lipoyl-binding-protein
MKVFPRRRGAVLVNSALGVALLAAAALAYTTLDSGTSSAAGKTQTRTATVAKGTVLATVSGSGTLTSPSDSSQDFVTGGRLTSVKVAVGDTVKKGQVLATVDTTEAQQQVAAAQSALNTADANLTKAQAGVTTTTTSQLPGTGSGGSGGGSGSGGRGGQQTPTPQTTTVTTTKVDDAQVAQAQQQVDSAKTQLANAQTALTGTTLYASADGTVASIAGKVGDTVGSTGGTPSSGSGNSKSSSGSSSSSSSSGTPSGFIVLTNPSGMQVSAAFSELDSLKLKKGEAATVTLNAQSDTVLNATVLSVSSLPTTSGGSAGSSGAVQYGALLQISGDTSKLRTGLSATISVTTGEADNALSVPTAALQGTGSSRTATLVHEDGSTERVDVTVGIEGDATVQVVSGLQAGDKVQLTATTAGTGNGFPGGGFPGLTGGAGGFGGGTGRGGAGGTGGGGGRSGGGTGGGGGGRG
>NZ_CP025394.1|WP_158702262.1|4572181_4572418_+|hypothetical-protein
MILGFAPVIVAGVALTVRAVLRRSWADAGAAVLTPTGMVLGWLCFQRHLVWAGAGAAVCGLALLVLIQKRSGSAGNSL
>NZ_CP025394.1|WP_104817421.1|4586234_4588007_+|GAF-domain-containing-protein
MEISQDQPPHRVPEIASLGLDTLVTEVSERLQSAAAVTDRMQRLLEAVVSVGAGLDLHATLQRIAHAAAELVDARYAAIGVISPHTDGLSDFIHIGVDDETAARIGELPAGRGILGVLIDHPEALRLADLAADPRSSGFPPHHPPMKSFLGEPIRIRDEVFGNIYLTEKQTGGPFTPEDEQVVHALAAAAGVAIENSRLYEEGLRRERWIAGAAAVTTALLSTDEAQVALTVAAEQVRELAGAALGMILLPTGDGQMRVAHASGEAAEFVTGELMPRSGFAAKLLEGESAYLDDMSTDPTVVLRLARSFGPSMAVPMIAAGRVLGGLVVWRAKGAAPFMEAEKQLAETFASQSALALRLAEGQRDQQRLAVFQDRDRIARDLHDLVIQRLFATGMMMESAARRAVVPEVRTGIAKAVDELDATIQEVRTTIYALQHDDTGNEPDTLRTRVLREGSQAAAALGFKPSMTFTGPVESLVGEKTGRQLLAALREMLSNTARHARASRVGVDVDATVHLDADGHPVPGDPESIDRAGRPGVLLTVTDDGVGIPDGGRRSGLLNLTRRAEALGGDAWHEPGPYGKGTRVRWSARL
>NZ_CP025394.1|WP_168219616.1|4588009_4588852_-|Cof-type-HAD-IIB-family-hydrolase
MREDGRVTTSSPRTRLIATDLDGTLLCAGGTVSDRTAAALAAAEAAGIQVVFVTGRPPRWMQQVSPHIGGHGVAICSNGGAIVDVRRGELLESFPLTAGAVLAIVTAMRAELPGVSFAFEHPQGWAREPEYELRMWGDDVEHEVAPAEELIADGRVAGLFKVLAKHPTLDPDTFLAEARRAAGHLAEITRSAPVAMVEISALGVTKASTLESWCREQGIDRTEVVAFGDMPNDLEMLAWAGHSYAVANAHPEVLAAVSRHTVSNDKDGVAAVVEQLLAEL
>NZ_CP025394.1|WP_104817423.1|4588923_4589853_-|hypothetical-protein
MRKPVRRTLTSLAATTALALTLAACGSGGSGSGSGDSKADMGGMPGMSTSSGASNSATHDMSAMGGNATDGDGLAAEQAGYRLDPIGGLPAAGTPGAFTFRITAPGGAPLTAFTAEQTKDLHFYAVRSDLSGFQHLHPTMAADGTWTAPLAALRPGAWRVYTQLTPAEGPGKGTMMVLSRPLTVPGQAADTPLPAAAESTTVDGYTVTVAGKPVAGQAVPLTVTVSKDGRPVTDLQPYLDTYAHLTAFHAGDQAFAHLHPQTPVGTGTGTGGPSLPFHAELPKAGDWRLFLQFQTAGTLHTAALTLKVS
>NZ_CP025394.1|WP_104817424.1|4589929_4590328_-|hypothetical-protein
MARERRALTRLYVLCAVLAGLFLMHGSPASAASGCHRTSAETVRSMPHHAMVADRSTEGPEAAPGEGGHGHAGEVCLATPGRDGQPVATPGPAPITVPAALPALGGGAVVDGAEGSRAPPEDLLLKVCVART
>NZ_CP025394.1|WP_158702264.1|4590427_4591009_-|hypothetical-protein
MARRGMAVAAGVLLAAVGVVGCGPEKGSSQAGPAPVATVTVTAAPTAPAVPTATGTPAPVPGKSQAAGDAPGVSCTEPTVKAGDKVVIPGARPKQAIMFAKVAQFACDPGGGHFVGDKAPETFQFAAGAKAQLVLDDGTYRDVLVGDLWVHIGDCLDGGANVQPPLSCSNFPAYEITQNAKGEITAIKELWHS
>NZ_CP025394.1|WP_104817426.1|4591165_4594930_+|RHS-repeat-protein
MSNQIVKALEHAAEKIGTAIAKDAGKAVKDLYHSAGQNLKKVAANVREVEEKHAKDLAKTFEHDTKGVPHPRSGGGTGPKGHDHPKGRGRDQVKDPRTEGRDHTSRKCPGEPVDIATGRMFIDQTDASLPGSLPLHFTRSFESGLRTGRWMGTKWLCPFDERLELDEAGVVHIRPDRITQAYPHPEPGDPVLASAGSRHQLDRTDDTFTVTDPATGLVKEFTPTPDGTEALLTTVRDRHGRHYTLTYDPDGTPLAITHSGGYRLNVTVEHTRITALRLATPDGDVMLMRYGYTDGHLTAVYNSSGKPMRFANDTAGRILSWTDRNNSQYRYTYDPFDRVTDEGGTTGALRFTFTYADPDPATGLRTHTETNALGHTTTYLINHHAQVTAVTDALGHTTSYERDDYDRLLSETDPLGRTTRYTYDGAGDLITITRPDGEQATATYLDHLSLPTEITEPGGATWHQTYDENGLRTALTNPLGATTHYTYDDHGHLATVTDALGHTTRIRCNPAGLPVEITDPTGSVTRYQRDAFGRTTAVVDPMGATTKLGWTSEGRLSSRTTADGATETWAYDGEGNMIAHTDQLGRVAAYEYTHFETLAARTTPDGARYTFAHDAHMQLTTVTDPLGRQWTYDYDRAGRLVGETDFDGRAVSYQLDAAGQAVARTNALGEQIRYTYDALGRASTKESDGRTTLYRYDATGNLIGAVDPDTELIRTLDVLGNLLSESVNGRTITFGRDVLGRRTSRRTPTGHRTSWTYDAAGRPSSLGTSGGDIGFTYDEAGREHERTIANHLTLTSVWDDRHRLTGQTLSTPSTVLQQRGYTYRADGNLVGVDDLLAGPRVFELDPADRITAVRAADWSETYAYDPVGNLTEADWPATRGTRASLGARTYLGTRLTTAGRIRYEHDAAGRTTLRQVTRLSRKPDSWHYSWDGENRLAGVTTPDGTRWRYRYDPLGRRIAKQRMGADGATVEEQTDFTWDGANLAEETTRAPHLPGPYTLSWDHDGLRPLAQTETLTTATVTEDGQSEVERRFFAIVTDLIGTPTELVDPATGVIAWRATSTVWGHTTWPTDSTTYTPLRFPGQYFDPETRLHYNVHRYYDPETARYTSPDPLGLFPAPNPDTYVTNPHLRSDPLGLSPHDHATDGDVVRLFKAPQKGTGEQQYRNGYQKDDFPGGPHDPYMDGKAYFAKEERGLADKYAKHYGEGVMEIQIPVAEYNRLFQQYEAKYEGGPLIEVPIPNTALEELNKFPRFWHR
>NZ_CP025394.1|WP_104817427.1|4594926_4595196_+|RNA-binding-protein
MTDTAEWEAAKRDFPIGHPVTGRIAAVRPFGMFVALPGRPEVIAVLDAISYHPDQDPIPPEQWPGVGEEIGAVVSSHAEHNHQIKLRVG
>NZ_CP025394.1|WP_158702265.1|4595561_4595708_+|hypothetical-protein
MEALFDGDPQARSLLERIRAGTSHTAGDRARRAVLRTRIDELAADLYD
>NZ_CP025394.1|WP_104817428.1|4596819_4597707_-|LLM-class-flavin-dependent-oxidoreductase
MRLSTVILPIHRWSEGQKIWQRAEDLGFHAAYTYDHLSWRSFRDEPWFGSVPTLTAAACATERIRLGTLVTSPNFRHPVTLAKELITLDDVSGGRVTLGIGAGGTGFDATAMGQEAWSPRERADRFAEFLPLLDELLTTDATTREGTHYSAVEARNIPGCVQTPRLPFYVAATGPRGLKLAAEHGQGWVTYGDPRGPADVPVEQAPEVIAAQLAKLTTACEAVGRDVAGLEKVLLQGSTAEKPLQSLDAFVDWAGRYQEIGITELVIHWPVPDSIFANDLAVFEQIATEGLAQLA
>NZ_CP025394.1|WP_104817429.1|4597781_4598081_+|hypothetical-protein
MYYTSAMDTPRPGKTRVTSVSLQAETLEAIRARAGRQGVSSYIEEAVQRHLQREVIDEYIAASEAEHGPVDAAEVAAKAERIRAHHAAHRGDAAPADAA

Crispr_ID: NZ_CP025394_11

• CRISPR_ID: NZ_CP025394_11
• CRISPR_location: 5615988-5616084
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_11

Consensus_repeat	Method
CCAGGGGCGCGGGGAACTGCGCG	CRISPRCasFinder

spacers of NZ_CP025394_11

>11.1|5616011|51|NZ_CP025394|CRISPRCasFinder
AGGTCGGAAGAAGCGGGCCGTACGCCGACCGGAGGGCGCCAGTTGCACTGT

CRISPR arrays and Neighbor proteins around NZ_CP025394_11

CRISPR arrays

The CRISPR arrays of NZ_CP025394_11

>merge|NZ_CP025394|11|5615988-5616084|CRISPRCasFinder
CCAGGGGCGCGGGGAACTGCGCGAGGTCGGAAGAAGCGGGCCGTACGCCGACCGGAGGGCGCCAGTTGCACTGTCCAGGGGCGCGAGGAACTGCGCG

>NZ_CP025394|11|10|5615988-5616084|CRISPRCasFinder
CCAGGGGCGCGGGGAACTGCGCG	AGGTCGGAAGAAGCGGGCCGTACGCCGACCGGAGGGCGCCAGTTGCACTGT
CCAGGGGCGCGAGGAACTGCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104818181.1|5607398_5608109_+|RNA-polymerase-sigma-factor-SigE	unknown	unknown	gnl|CDD|236606
NZ_CP025394.1|WP_104818190.1|5617822_5618938_-|magnesium/cobalt-transporter-CorA	unknown	unknown	gnl|CDD|213364
NZ_CP025394.1|WP_104821084.1|5613042_5613594_-|DUF1003-domain-containing-protein	unknown	unknown	gnl|CDD|377629
NZ_CP025394.1|WP_104818192.1|5619995_5620592_-|MarC-family-protein	unknown	unknown	gnl|CDD|225006
NZ_CP025394.1|WP_104818188.1|5615089_5615917_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133382
NZ_CP025394.1|WP_104818194.1|5621792_5622431_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818185.1|5611257_5611719_+|redox-sensitive-transcriptional-activator-SoxR	unknown	unknown	gnl|CDD|133385
NZ_CP025394.1|WP_104818195.1|5623176_5624076_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_CP025394.1|WP_104818193.1|5620767_5621628_-|PHP-domain-containing-protein	unknown	unknown	gnl|CDD|223686
NZ_CP025394.1|WP_104818191.1|5619327_5619978_+|suppressor-of-fused-domain-protein	unknown	unknown	gnl|CDD|377450
NZ_CP025394.1|WP_104818196.1|5624273_5626910_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NZ_CP025394.1|WP_168219625.1|5622717_5622864_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104821083.1|5606461_5607121_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|226607
NZ_CP025394.1|WP_104818184.1|5610838_5611162_-|ferredoxin-family-protein	unknown	unknown	gnl|CDD|224069
NZ_CP025394.1|WP_104818189.1|5616141_5616705_-|hypothetical-protein	unknown	unknown	gnl|CDD|274679
NZ_CP025394.1|WP_168219624.1|5616842_5617802_+|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NZ_CP025394.1|WP_104818182.1|5609486_5609906_+|Sec-independent-protein-translocase-subunit-TatB	unknown	unknown	gnl|CDD|179287
NZ_CP025394.1|WP_104818186.1|5611802_5612963_-|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl|CDD|378455
NZ_CP025394.1|WP_104818187.1|5613682_5614987_-|magnesium-transporter	unknown	unknown	gnl|CDD|225148
NZ_CP025394.1|WP_104818183.1|5610178_5610811_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104818181.1|5607398_5608109_+|RNA-polymerase-sigma-factor-SigE	gnl|CDD|236606	PRK09647, PRK09647, RNA polymerase sigma factor SigE; Reviewed.	4.40961e-117
NZ_CP025394.1|WP_104821084.1|5613042_5613594_-|DUF1003-domain-containing-protein	gnl|CDD|377629	pfam06210, DUF1003, Protein of unknown function (DUF1003). This family consists of several hypothetical bacterial proteins of unknown function.	2.51455e-45
NZ_CP025394.1|WP_104818192.1|5619995_5620592_-|MarC-family-protein	gnl|CDD|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	1.01365e-42
NZ_CP025394.1|WP_104818188.1|5615089_5615917_-|MerR-family-transcriptional-regulator	gnl|CDD|133382	cd01107, HTH_BmrR, Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BmrR and YdfL of Bacillus subtilis, and related proteins; N-terminal domain. Bmr is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. BmrR is comprised of two distinct domains that harbor a regulatory (effector-binding) site and an active (DNA-binding) site. The conserved N-terminal domain contains a winged HTH motif that mediates DNA binding, while the C-terminal domain binds coactivating, toxic compounds. BmrR shares the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	1.59366e-41
NZ_CP025394.1|WP_104818185.1|5611257_5611719_+|redox-sensitive-transcriptional-activator-SoxR	gnl|CDD|133385	cd01110, HTH_SoxR, Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator. Helix-turn-helix (HTH) transcriptional regulator SoxR. The global regulator, SoxR, up-regulates gene expression of another transcription activator, SoxS, which directly stimulates the oxidative stress regulon genes in E. coli. The soxRS response renders the bacterial cell resistant to superoxide-generating agents, macrophage-generated nitric oxide, organic solvents, and antibiotics. The SoxR proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the unusually long spacer between the -35 and -10 promoter elements. They also harbor a regulatory C-terminal domain containing an iron-sulfur center.	6.48682e-69
NZ_CP025394.1|WP_104818195.1|5623176_5624076_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.52962e-15
NZ_CP025394.1|WP_104818193.1|5620767_5621628_-|PHP-domain-containing-protein	gnl|CDD|223686	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only].	1.26458e-42
NZ_CP025394.1|WP_104818191.1|5619327_5619978_+|suppressor-of-fused-domain-protein	gnl|CDD|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	3.82645e-28
NZ_CP025394.1|WP_104818196.1|5624273_5626910_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	2.36848e-132
NZ_CP025394.1|WP_104821083.1|5606461_5607121_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	7.95208e-44
NZ_CP025394.1|WP_104818184.1|5610838_5611162_-|ferredoxin-family-protein	gnl|CDD|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	3.63909e-11
NZ_CP025394.1|WP_104818189.1|5616141_5616705_-|hypothetical-protein	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	0.00240136
NZ_CP025394.1|WP_168219624.1|5616842_5617802_+|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	5.08923e-10
NZ_CP025394.1|WP_104818182.1|5609486_5609906_+|Sec-independent-protein-translocase-subunit-TatB	gnl|CDD|179287	PRK01371, PRK01371, Sec-independent protein translocase protein TatB.	3.04814e-43
NZ_CP025394.1|WP_104818186.1|5611802_5612963_-|Mrp/NBP35-family-ATP-binding-protein	gnl|CDD|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	1.51212e-129
NZ_CP025394.1|WP_104818187.1|5613682_5614987_-|magnesium-transporter	gnl|CDD|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	6.72296e-47
NZ_CP025394.1|WP_104818190.1|5617822_5618938_-|magnesium/cobalt-transporter-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.86433e-166

Protein sequences

>NZ_CP025394.1|WP_104818188.1|5615089_5615917_-|MerR-family-transcriptional-regulator
MFTIGDFAKHGRVSVRMLRHYDAIGLLRPARVDPHTGYRGYEAGQLAELNRVIALKDLGFTLEQVGAILGDLVGAEELRGMLRLRQAELAALVAETTTRLTRVEARLRTIESEGQMPTNDVVLKQIPAVRVAELSATAASYQPGDITPVISLLFPELCRLVAAAGLTPAGASLAYYVDGPDGTVEVHAALPVAAGVTGAGAGHGFAVVDLPAIESAATAVHHGSMDGVLATEQALVRWIEETGHRATGHSRELYLECEGAPETWVTELQTPVVMR
>NZ_CP025394.1|WP_104818187.1|5613682_5614987_-|magnesium-transporter
MAGPGSRVFISHLSGVAVFDPNGDQVGRVRDVVVSLRIGGRPPRVLGLVVEVVARRRIFLPMTRVTSLESGQVLTTGVINMRRFEQRPSETLVLAELLDRTVTRTKTHEEVTVLDVAMVQTRVREWEITKVFVQTGKLSRLRKAKGETLTLDWSAVTGFALAEEGQGAANLLATFEQLRPADLANVMHHLSSKRRAEVAAALDDDRLADVLEELPEDDQVEIIGKLQEERAADVLEAMDPDDAADLLSDLPEEDAERLLRLMEPEDAAEMRRLLSYEEDTAGGLMTTEPIVLEPDATVAEALARVRISDNKPALAAQVYVCRPPNETPTGKYLGTVHFQRLLREPPFTLVGSLVDDDLDPLPPDTPLPLITSYLATYNMVAAPVVDEADHLLGAVTVDDVLDHLLPDDWREAALHGLNGSDLEHGHESEDIRGR
>NZ_CP025394.1|WP_104821084.1|5613042_5613594_-|DUF1003-domain-containing-protein
MRELRVREGSSTRTEQPSSSAARARLDQPRTSRPGLLTLPTYDPESFAKLSERIARFLGTGRFIVWMSVVILCWVAWNVFLPPAVRFDEYPFIFLTLALSLQASYAAPLILLAQNRQDNRDRVNMEQDRARSDRNIADTEYLTREVAALRQGLGEVATRDFIRSELQSLLKEIDERRDASEML
>NZ_CP025394.1|WP_104818186.1|5611802_5612963_-|Mrp/NBP35-family-ATP-binding-protein
MANETEVAVGVTEESVRAALATVNDPEINRPITEIGMVKSVEIGDGGAVRVGVYLTVSGCPMRETITSRVTEAVGAVAGVTGVEVELDVMSEEQRKELSQLLRGGAPEREIPFAKPGTLTRVYAVASGKGGVGKSSVTVNLAAALAAQGQKVAVVDADIYGHSVPRMLGVEGRPTQVQDMIMPPSAHGVKVISIGMFTPGNAPVVWRGPMLHRALQQFLADVYWGDLDVLLLDLPPGTGDIAISVAQLVPNAEILLVTTPQQAAAEVAERAGTIALQTHQKIVGVIENMAGMPCPHCDEIVDVFGTGGGQTVADALTRSVGATVPVLGSIPIDVRLREGGDDGTPVVLAAPDSPAGTALHAIAAKLGNRQRGLSGLSLGLTPKNKF
>NZ_CP025394.1|WP_104818185.1|5611257_5611719_+|redox-sensitive-transcriptional-activator-SoxR
MTQQPGEARATPDDRLAIGEVSARTGAAVSALRFYEELGLIASERDGRNQRRYPRHMLRRIALISVAKRIGIPLQDLRETFADVPLDRPPSHQEWQRASRGWKARLEERRQTIERLEAELTGCIGCGCLSMKACALLNPGDTLAEDGAGPRRL
>NZ_CP025394.1|WP_104818184.1|5610838_5611162_-|ferredoxin-family-protein
MTFVIAVPCVDVKDKACLDECPVDCIYEGERMLYIHPDECIDCGACEPVCPVEAIYYEDDTPEPWREFNRANVEFFDDLGSPGGSAKLGLIPKDHPIVAALPLRDTV
>NZ_CP025394.1|WP_104818183.1|5610178_5610811_+|hypothetical-protein
MVGAQAGPPADPLAPYLAADFPWYGLDEGWTGRRWLMQAGAGQTARGAQRGSVDYGTLGHGDEPARQYEPRDMRRFAVVVTMARRDVRRSADNTGTLEATSASSAAWLAGSGLLAATWPGQLDRALRQDWLDQQTALAWDLADDLDGPGWSTLTLPVNGLPQPFRYRESEYGWVLAGEAPGVLLGAYGRGVSAYGAGFSAVQDLTNYDGR
>NZ_CP025394.1|WP_104818182.1|5609486_5609906_+|Sec-independent-protein-translocase-subunit-TatB
MFADIGPLEVVTLVIMAVVIFGPDKLPKLIQDTMGFIRKIRSFADSAKEDIRAELGPEFKDFDFEDLHPKTFVRKQLLGGNEDPLGFKEIRDGLDFKSVLNDEPTKPAPPAPNLVKPAAPDTGTPLAKGERPPYDLDAT
>NZ_CP025394.1|WP_104818181.1|5607398_5608109_+|RNA-polymerase-sigma-factor-SigE
MNKSAQIPMDEPAATEGPEAAAPAPRAAFDADAQTWTPPSWEEIVEAHSARVYRLAYRLTGNQHDAEDLTQEVFVRVFRSLSTYTPGTFEGWLHRITTNLFLDMVRRRQRIRFDALADDAAERLASREPSPAQHFSDTHFDADVQQALDTLAPEFRAAVVLCDIEGLSYEEIAATLGVKLGTVRSRIHRGRSHLRAALKHRAPGTAPGRVRRGGQGEPVAVGAEAGPSGGGERGRS
>NZ_CP025394.1|WP_104821083.1|5606461_5607121_-|class-I-SAM-dependent-methyltransferase
MRSTTGEAAITEFGSAQVALADTYVGEDAVLTYARALAARVGVRPIGPSGGACLRLLAAALDAKAVAEIGTGTGVSGVYLLRGMRPDGVLTTVDSEPVHQQYARAAYQAAGFAANRSRVIPGQALDVLPRLADGQYDLVLCDGDPAESSSYLAESLRLLRPGGMVCFEGVFHQGRLAEPNHRDPGTHALRELVQEVRESDALLPALLPVSDGLLCAVKR
>NZ_CP025394.1|WP_104818189.1|5616141_5616705_-|hypothetical-protein
MEPTTPATAAAATATAAIEERALLEEAAKKSGLLWVRADGQPQARALWHAWHDGAVVVVGDGIEQPLHGLTAGAGAEVTVRSKDKWGRLTAWPARVSELAPRSEGWLGAVEELKGKRLNAPDTDTIDERWARECRVLRLEPAGPLTEQPGAMPEASHAAVPMASPATTRKPIPAGLPKLVAKGKLGR
>NZ_CP025394.1|WP_168219624.1|5616842_5617802_+|DMT-family-transporter
MPTVARPDAAAQTPAPSLRPGGPPAASAARPALPKLDLLLLAVSIGGISLSAPLISATAAPALAIAFWRNVMSVGVLGPYALLRHRAELRGIGRRALLLATAAGVLLAVHFALWMPSLRMTSVASATAMVTTTPLWTILLMRLLGHRAPRLVRIGMCVAFLGVLTLTGVDLSLSPQALAGDALALGAGLAAAGYMLLGAEVRKTVSTTAYTLVCYATTAVVLLGICLVTGTGLSGWSAGAWWQIALLMVAAQLLGHSLSNRVVRTLGPSVTSTAILLETPGAALIAALWLGQWPPAGAYPAVAVILLGLVLVARGSREG
>NZ_CP025394.1|WP_104818190.1|5617822_5618938_-|magnesium/cobalt-transporter-CorA
MSMMNNLRAVVRPQRRRPDATFDPLHPGHGVSAVVDCAVYQAGKRHGETCSPREAVQRVRNARQQSAESFSWIGLHEPTEAEFEGIAQRFGLHPLAVEDAVHAHQRPKVERYDEVLFAVFKTIRYVEHDQLTPTSEVVETGELMVFVGADFVITVRHGGHGSLKDLRRRLEGDHDGTGLLCKGPAAVLHAIADQVVDDYLLVADRLQTDVDEIEFDVFANRGGRGADVGRVYQLKREVLEFKRAVAPLLRPMQLLSEAEKAPIGPEMRKYFRDVADHLARVTEQVHGFDELLNSLLQANLAQVSVAQNEDMRKITAWAAIFAVPTMITGVYGMNFDYMPELHHRYGYPIVLGVITVICIGMYKGFRRNGWL
>NZ_CP025394.1|WP_104818191.1|5619327_5619978_+|suppressor-of-fused-domain-protein
MAHDFPLFGDFSDNSAAGPDEHTREAVLAAVEARLLSTFGEPSGRAGVTFLGADRIEVLRFGPDAEGLVRYATLGMAAAPMNDPSAMLADPVRGPRVELVLTVRGGRDEVLRTLATFAATPQVEGLIVAPGASLDLGQPLWPGAPFTSVLTAEPGGLVPDLALAAPADPVRFLPLLPMTPNEAAFKRVQGAAALEERWLKHGTDLRDPERKGVALG
>NZ_CP025394.1|WP_104818192.1|5619995_5620592_-|MarC-family-protein
MKTFGSLFVTLFVIMDPPGTIPIFLALTSGRAARTQRKMAWQAALVALGVITCFGLFGQQILDYLHVSIPALQISGGILLLLIALDLLTGKIDEPTQTKDVNVALVPLGTPLLAGPGAIVAVILAVQGADGATEELAVWTAIVAMHVVMWLTMRFSLVIIRIIKEGGVVLITRLSGLLLSAIAVQLVASGVFGFIDTR
>NZ_CP025394.1|WP_104818193.1|5620767_5621628_-|PHP-domain-containing-protein
MRIDLHAHSNASDGTDSPAELVANAVAAGLDVVALTDHDTVAGHAEAAEAVRALPPGSGLTLVPGAELSCVVGGISMHLLAYLFDPAEPEFAAERELVRTDRFRRGRAIVERCRELGAPITWEQVQRIAGEGSVGRPHIASALVEAGVVATVSDAFTPEWLVNGGRADVRKHETDPVAAVRLVRAAGGVPVFAHPGAAKRGRTVSDQVIADLAAAGLGGLEVDHMDHDEGARTHLTGLAAELGLFTTGSSDYHGTRKTVRLGEYTTSPESYEALLAQATGAKPITA
>NZ_CP025394.1|WP_104818194.1|5621792_5622431_-|hypothetical-protein
MRGEPSCPRCAGRVRAPGLFSDTWQCDQHGAVHPMQPVLPPSVEALGVAVARSQVPVWLPWPLPVGWLYTGIAHAGDDLSGARATAVACSGPAPLGGFGELVLVAEELGVGLGARYAGLPGPDPGPSVSLYKPADAKLMAAGRPTPMFHVPDAPADRAVFVGEARGLWLWAIVWPEQSALLMYDELVLTDLRDAGAELELLTCGALSPRLLT
>NZ_CP025394.1|WP_168219625.1|5622717_5622864_-|hypothetical-protein
MRFEILRLDDAQGTATDSLIADAATVRELVEAAARTGERLLIRPCKAA
>NZ_CP025394.1|WP_104818195.1|5623176_5624076_-|alpha/beta-hydrolase
MSTPPFLNLPGCARALRLATPRGEFAAHLAEPAGAVRGTALLVPGFTGSKEDFIALLAPLAEAGYRVVTVDQRGQYESGGPADPAAYAVAELAQDVLAMTGALTETATGLAGDGPLHLLGHSFGGQVVREAVLAAAAGAREGAEAALPWRSLTLLATGPGAIEPGEAARTKLLVDALGSMDLESIWQVMQQMEEGSGATRPRAEIAAFLHRRWLANVPTALAAMGAHLIAAPDRVAELAAVPLPKLVLSGVRDYAWPVEEQTAMAERLGAARVTVPDAGHSPNAEQPAATAAALAAFWA
>NZ_CP025394.1|WP_104818196.1|5624273_5626910_-|DEAD/DEAH-box-helicase
MTLPVALTGHDVIGQAKTGTGKTLGFGLPLIERVVVRADIDAGRATEDQLSDHPQALIVVPTRELCTQVTNDLQTAGKVRNVRVLAIYGGRAYEPQVEALQKGVDIIVGTPGRLLDLAGQRKLNLSKVRALVLDEADEMLDLGFLPDVEKIITMLPAKRQTLLFSATMPGQVISLARRYMSQPTHIRAAAPDDTGHTVANIEQHVFRAHSLDKVEMVARILQAEGRGLAMIFCRTKRTAADVADQLTQRGFAAGAVHGDLGQGAREQALRAFRSGKVDVLVCTDVAARGIDVEGVTHVVNYQCTEDEKTYLHRIGRTGRAGASGTAVTLVDWDDIPRWQLINKALELNFNEPEETYSTSPHFYELLKIAPGTKGVLPRSERTRAGLGAETLEDLGETGGRGGRGGRDRDRDRGGRGGERGGRGEAGPGARTAEQRPARPPRERRRTRGGSSAANPAVEAPATEAPLTGPAAEGEAAPRRRRRRNRGGSAAAAAANQAVEAPATTEAPAPAPAMEAPAAGEAAPSRRSRSRRGRSAGQPTAAVETATAAPVAPVETAPAAPAAAPVAVAAAVVETVEVPAPAKRTRTRKAAAAATTTAPVETEAAVVAEVPAPRSRKAAAPKTAAPKAEVLEVVAEAVVEAPVKKTAARKTAAKKVAEAVVAEATEAAPAKRTRKAAAPKAEVVEVVAEVVVEAPVKKTAARKTAAKKVAEATVEIPAPAKRTRKAAAPKAEVVEAVAEVIVEAPVKKTAARKTAAKKAAEAVVAEATEAAPVKRTRKAAAPKAEAVAEVVEAPAKKTTTRKTAAKKAAEAVVAEATVEIPAPAKRTRKAAAPKAETAEVTEAPAKAPRARKAAATAPAEAPVKKTAARKTAAKAPAKS

Crispr_ID: NZ_CP025394_12

• CRISPR_ID: NZ_CP025394_12
• CRISPR_location: 5925049-5925146
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_12

Consensus_repeat	Method
CTCGCGCAGTTCCCCGCGCCCCTG	CRISPRCasFinder

spacers of NZ_CP025394_12

>12.1|5925073|50|NZ_CP025394|CRISPRCasFinder
GATAGTGCAACTGGCTCGGAGAAGTAGGCAAGATGACCGTTTCTTCCGTA

CRISPR arrays and Neighbor proteins around NZ_CP025394_12

CRISPR arrays

The CRISPR arrays of NZ_CP025394_12

>merge|NZ_CP025394|12|5925049-5925146|CRISPRCasFinder
CTCGCGCAGTTCCCCGCGCCCCTGGATAGTGCAACTGGCTCGGAGAAGTAGGCAAGATGACCGTTTCTTCCGTACTCGCGCAGTTCCCCGCGCCCCTG

>NZ_CP025394|12|11|5925049-5925146|CRISPRCasFinder
CTCGCGCAGTTCCCCGCGCCCCTG	GATAGTGCAACTGGCTCGGAGAAGTAGGCAAGATGACCGTTTCTTCCGTA
CTCGCGCAGTTCCCCGCGCCCCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104818400.1|5921154_5922405_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|226984
NZ_CP025394.1|WP_104818401.1|5922405_5923038_+|DUF4276-family-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818397.1|5919053_5919350_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl|CDD|178810
NZ_CP025394.1|WP_104818403.1|5924786_5924969_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818409.1|5937679_5938585_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP025394.1|WP_104818396.1|5917231_5918845_+|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl|CDD|238923
NZ_CP025394.1|WP_104818412.1|5943154_5943658_-|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NZ_CP025394.1|WP_104818399.1|5920847_5921087_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818406.1|5933813_5934338_+|acetolactate-synthase-small-subunit	unknown	unknown	gnl|CDD|183365
NZ_CP025394.1|WP_104818410.1|5939045_5939723_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP025394.1|WP_104818402.1|5923034_5924543_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl|CDD|235489
NZ_CP025394.1|WP_104818398.1|5919357_5920851_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl|CDD|234572
NZ_CP025394.1|WP_104821115.1|5914614_5916927_+|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NZ_CP025394.1|WP_104821117.1|5928819_5931654_+|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|236645
NZ_CP025394.1|WP_104818407.1|5934442_5935441_+|ketol-acid-reductoisomerase	unknown	unknown	gnl|CDD|235491
NZ_CP025394.1|WP_104821116.1|5913601_5914600_+|methionine-synthase	unknown	unknown	gnl|CDD|239426
NZ_CP025394.1|WP_158702358.1|5937501_5937657_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818405.1|5931923_5933777_+|acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|236098
NZ_CP025394.1|WP_104818404.1|5925195_5928291_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|226415
NZ_CP025394.1|WP_104818408.1|5935663_5937244_+|phosphoglycerate-dehydrogenase	unknown	unknown	gnl|CDD|237436

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104818400.1|5921154_5922405_+|AAA-family-ATPase	gnl|CDD|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	1.33227e-25
NZ_CP025394.1|WP_104818397.1|5919053_5919350_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl|CDD|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	2.4485e-36
NZ_CP025394.1|WP_104818402.1|5923034_5924543_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl|CDD|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_CP025394.1|WP_104818409.1|5937679_5938585_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.24737e-39
NZ_CP025394.1|WP_104818396.1|5917231_5918845_+|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	2.84658e-99
NZ_CP025394.1|WP_104818412.1|5943154_5943658_-|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	7.01754e-18
NZ_CP025394.1|WP_104818410.1|5939045_5939723_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.4858e-30
NZ_CP025394.1|WP_104818405.1|5931923_5933777_+|acetolactate-synthase-large-subunit	gnl|CDD|236098	PRK07789, PRK07789, acetolactate synthase 1 catalytic subunit; Validated.	0
NZ_CP025394.1|WP_104818398.1|5919357_5920851_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl|CDD|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_CP025394.1|WP_104821115.1|5914614_5916927_+|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP025394.1|WP_104821116.1|5913601_5914600_+|methionine-synthase	gnl|CDD|239426	cd03310, CIMS_like, CIMS - Cobalamine-independent methonine synthase, or MetE. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme catalyses the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to L-homocysteine without using an intermediate methyl carrier. The active enzyme has a dual (beta-alpha)8-barrel structure, and this model covers both the N-and C-terminal barrel, and some single-barrel sequences, mostly from Archaea. It is assumed that the homologous N-terminal barrel has evolved from the C-terminus via gene duplication and has subsequently lost binding sites, and it seems as if the two barrels forming the active enzyme may sometimes reside on different polypeptides. The C-terminal domain incorporates the Zinc ion, which binds and activates homocysteine. Side chains from both barrels contribute to the binding of the folate substrate.	5.10771e-67
NZ_CP025394.1|WP_104818407.1|5934442_5935441_+|ketol-acid-reductoisomerase	gnl|CDD|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
NZ_CP025394.1|WP_104821117.1|5928819_5931654_+|EAL-domain-containing-protein	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	3.65885e-65
NZ_CP025394.1|WP_104818406.1|5933813_5934338_+|acetolactate-synthase-small-subunit	gnl|CDD|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	2.40443e-94
NZ_CP025394.1|WP_104818404.1|5925195_5928291_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	1.27991e-36
NZ_CP025394.1|WP_104818408.1|5935663_5937244_+|phosphoglycerate-dehydrogenase	gnl|CDD|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0

Protein sequences

>NZ_CP025394.1|WP_104818403.1|5924786_5924969_+|hypothetical-protein
MIEYELIQQRNAELQRVARDYVLAREARSGARSFRETLRSRFARRASVAPAVTTARLGEC
>NZ_CP025394.1|WP_104818402.1|5923034_5924543_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MSTMNLVSYDDALASYDPVMGLEVHVELGTKTKMFCGCSTELGAEPNTQVCPTCLGLPGSLPVVNAIGVESAIKIGLALNCEIAEWCRFARKNYFYPDMPKNFQTSQYDEPIAFNGYLDVQLEDGSTFRVEIERAHMEEDTGKSSHVGGATGRIHGATHSLLDYNRAGIPLIEIVTKPIEGAGERAPEVAKAYVRELREVILSLGVSEARMDKGQMRCDVNLSLRPNGTEKFGTRSETKNVNSLRSVERAARFEIMRHATVLTDGGTIVQETRHFHEEDGSTTSGRIKDNAEDYRYFPEPDLVPIAPARDWVEELRAALPELPRVRRARLQGEWGLSDKDMQSVLNAGAVGPILETIAAGAPADQARKWWMGELARRANETGTELAEQPITPAQVARVCALVAEGKLNDKLARQVIEAVLAGEGEPDAVVEARGLAVVSDDSALGAAVDQAIAENGAIADKIRDGKVAAVGALVGAVMKATRGQADAARVKDLILAKLGVEG
>NZ_CP025394.1|WP_104818401.1|5922405_5923038_+|DUF4276-family-protein
MGDRPLVPALVAEGPSDEPFLATLIVRQLEELLIAKAPRRVQVFACEVSPVRITGSGGAQAVIETAWELAQDCDLIFAHSDEKERDTAEKLVAELHARAQQAKAAVPVVLVPIRMTESWMLADRQAIARCVAGADLGAYPYKTPADVEKAHNSPGHPAYAKQVWQAIAGCGHESTDLLAQHIDLRLLSQLPSYQRWLADTEEALKAKGFL
>NZ_CP025394.1|WP_104818400.1|5921154_5922405_+|AAA-family-ATPase
MITQIRIDGFKSFVGFQLDVHPVTVLLGVNGAGKSNLFDALRLVSGIIHRGVRDTLSGDRRLAAHTLFHRGEGAPARDLEVMVGAVTETEDGPLPITIRVALRGGSKPFLDVYRSRVRLSGLRQTDWTDRLGYSAACRAELVAARQAFLARTPSGPEHTWLHTDQMPEPGADYFHEGLYEVAQQECATWFPYALEPTALRELGRPEDDGPLRPDGRNLAVVLDRISRESPERFTRLVADLAAIVPGARGIRTETIRTRGELDFEVEFQHTGWISPASLSDGTLRALALLAASWDQANPGTLLVEEVENGMHLTQVAELVRRLSRNVGLAADARGQSARQLILTTHSPALLAALRGDLSGSLVFLEQANRVDPESGAVSRVTAARPLRERGATDDPGESISPQAVTRLLRRLGQEVS
>NZ_CP025394.1|WP_104818399.1|5920847_5921087_+|hypothetical-protein
MSKIAKAKGFKHSKPGLLLSIGTSAFGAISLYKDIKKARGEQDTLLLANAVVGALALVTGTALLLRELKQLGDDDILLG
>NZ_CP025394.1|WP_104818398.1|5919357_5920851_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MSELIRYTAAQTANAIATGEVSAVEVAQAHLDRIGAVDEKVHAFLHVDTEGALSAARAVDAKRAAGEELGPLAGVPLALKDVFTTKGVPTTCGSKMLEGWVPPYDATLTTRLKDAGVVILGKTNMDEFAMGSSTENSAYGPTGNPWDLSRIPGGSGGGSAAALAAFEAPLAIGTDTGGSIRQPGAVTGTVGVKPTYGAVSRYGLVAFSSSLDQGGPCARTVLDAALLHEAIAGYDPMDSTSIDAPVPAVVEAARMRDVRGMRIGVVKEFAGEGYQAGVMQRFNESVELLRELGAEVVEVSCPSFTLALPAYYLIAPSEASSNLARFDAMRYGLRVGDNGERSAEQVTALTREAGFGDEVKRRIILGTYALSSGYYDAYYGSAQKVRTLISRDFDAAFAGVDVLVSPTTPTTAFPIGERADDPMAMYLADLCTIPSNLAGNAAMSLPVGLAPEDNLPVGLQIIAPAMADDRLYRVGGAVEAALNDKWGHTLLEEAPAL
>NZ_CP025394.1|WP_104818397.1|5919053_5919350_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MPGITREEVAHLARLSRLELAAEELDHFAEQLDVIIGAVARVSEVAGQDVPPTSHPLPLTNVMRADEVRPSLTPEQALAGAPAAEEQRFRVPQILGED
>NZ_CP025394.1|WP_104818396.1|5917231_5918845_+|bifunctional-diguanylate-cyclase/phosphodiesterase
MDRSTGGAPTRPPQGVAGAVLLLGVLLAGAAPLIPLAVLVYRHEPELLPLFAVPLAVLVAAWRIARDRARDQLTDPLTDLPNRHALLLAAQEAIADHEEDEGYSVGLILLDLDRFRSLNDALGHTAGDRLLVHISRRLHRALRSGPHNPTRSDPDEVFAQLPDSQGRPVVARMGGDEFAVLLPGVGCPDTLERMANALIAELAAPIRLDGLLLVLEASAGVCVYPRHAQDAEALLRRADVAMGHAQRRRSGVEQYDEARDIDTPYRIGLLGDLRRALETGEVQLHYQPKVAFDGRVVGLEALLRWERPGRGKVSPDEFIGLAESSGLMPRLTDYVLEAAVGQLSDWRRQGLEVQVAVNVSPRDVLNPGFAGRVAGHLARHGVPAHALQLEITERLLLDDSRLAADTLAELRRSGVGMSLDDFGTGHSSLVRLRSLPVGELKIDRSFVSRMVADHHDAAVVRCSVELAHSLGLTVVAEGVEDDETWERLHGLGVDAVQGWLVSAALPAEQATAWLMVHRTTAPKVEWLTPRPALPPTP
>NZ_CP025394.1|WP_104821115.1|5914614_5916927_+|NAD-dependent-DNA-ligase-LigA
MAAVEGWEDVPAEVRKRAAELAVELEEHRVRYYEQDAPTVSDAEFDALMRELEAIEAEHPVLVTPDSPTQKVGGGATDAFAKVEHRERLLSLDNAMDDEELSAWAERVAKELDGLEYHYLCELKVDGLAVNLTYERGQLVLAATRGTGRVGEDITTNVRTIKEIPHQLKGDHIPELVEIRGEVFLPTEAFAELNASFAAENDRRRAENEERAKEGKRPHALVKLFANPRNAAAGSLRQKDPLVTASRPLHMVVHGIGARVGFEIDNQSHAYQLLHDWGLPTAKHNRVVSSLEEVRAFIKQYGEQRHSVEHEIDGVVVKVDEIALQGRLGATSKSPRWAIAWKYPPEEVNGKLARIQVGIGRTGRATPFAVLAEPVKVAGSMVQYATLHNQEIVKAKGVLLGDTVVLRKAGDVIPEILGPVEDLRDGTETEFVMPTHCHECGTELRPMSEGDIDVRCPNAQHCPAQVRERLAYLGGRESLDIEGLGYVAATALTQPLEPAEAPVANEGDIFALTLEQLLPIKVKVRDQKTGLPKLDDKSGKEKVATFFANLKGEPKKTATLLLENLDKAKDRPLWRYVNGLSIRHVGPVAAQALAREFRDLDRIFAATEEELAAAEGVGPTIARSIKEWYEEEWHREIIEKWRAAGVVFVEEAAEAEGDRPLEGLTVVVTGTLAGHTRDGAKEALTSRGAKVTGSVSKKTDFVVAGDNPGSKYDKAVQLGLAVLDDAGFTVLLEQGPVAARALLGIEEAAPEESPGAAAETPEAEAEPTNG
>NZ_CP025394.1|WP_104821116.1|5913601_5914600_+|methionine-synthase
MEFPEIAGAATGVGSLPGTDAREAAKTAVGALEFLPHLPELPARGPGADMIGRSAGLLVELFAHVEPSGWRFSDRPGRDTRRAHSWLGEDLDALEEFTQGYEGPLKVQAVGPWTLAAAIELRNGERAVKDLGACRSIAESLTEGLLRHLADVRRRVPGAQLVLQLDEPSLPAVLAGSLKTASGFSRLRAVDRQLAEEVLRGVIGKVGAPTIVHCCAPGTPIPLLRRAGVAGVSVDFSLLTERDDDDLGEAVEAGTRILAGVVPSTDSGMSDAAGSVQGVRTLWRRLGLSPELLGRRVLVTPTCGLAGASPAYARKALSLSAQAARSLVDNPE
>NZ_CP025394.1|WP_104818404.1|5925195_5928291_+|helix-turn-helix-transcriptional-regulator
MLSRVEQLSVSPVFVGRGTETTALAQALERAGRGEPVAVLIGGEAGVGKTRLIEEFLDSAASETVVTTLGACLEVGAEGLPFAPMATALRRLHRQLGAELERAAEGMEGHLARLLPDFGEADAEPNDEFSRVRLFEHTARLFERLSAHRTLVLAVEDLHWSDRSTRELLAYLIRTLHRSRVLIVATYRADDLHRRHPLRPFLAELDRLRTVQRLELARFQRREVAAQLAGILGTKQLDRELVDRIHRRSEGNPFFVEELATAHREGSPAGMTDSLRDILLVRVEALPDETQRVLRIAAEGGSYVEHALLAAVLDEGDGEPVEECLLEALRTAVGANVLRPDTDGEGYRFRHALVREAVSDDLLPGERYRINRRYAAVLEADEALVCAADRPARLANYWYHAHDPARALPSALDAARAARRRNAFAEQLRMLERALGLWEEVSEEVQATTLRPYDWAETYPPCTCDPGTHDEGCDRLRLVDVLAEAVVAARRSGDPERGLSLSKRALKLVDETEHPERAAWFRMHRARLLGQLLRGGQDEEIEHAQRLVARRRPSAVQAEVFALAASHAMMMHPTETDIALAERAVQIAREVGAGTVEQHARMTLGTFRALQGDPEAGIALISDAVERARGLCAPDLHCRGLNNLASLLLGLGRAAEAEALAREGLALAGRTGLLGNTGALLIGNLGEALFALGRPAEAARVLVEWESEQCGGSYYEFLDRLSGELALERGESATAAACLHRARSAGRVVRLQHQVPAVRLAMRLAARDGRPLDARAELHAMLDFRAEHAARHPGLLPEGGCGWLLPALAEAAAVEADSRGLPAAAPGRAEALARIAGAAATLRPSAPLHIGWLRLLEGELARAEGCDDPAHWAAAVEVLREVEPGQPLLLALYRQAQATAAAGRREAAAELLREAAGLAAAREDTRLAREITHLAERAGLSLDGRRSEPEPPAEGAEALGLTPRERDVLRLLAQGRTNRQIAEELYISPKTASVHVSNILAKLAVGSRGEAAAVAHRLRLFPEAALLTAPA
>NZ_CP025394.1|WP_104821117.1|5928819_5931654_+|EAL-domain-containing-protein
MGDFGLAGAALAAALSCLLRGCTIGGPARPAWLLFGLSSTVVAFGNGVWGWYEVVLRTDPPPGSPAQYAFLLFAPLAITGLLVLAQRPRAATGWLCLLLDGWLVAGSLFTLAWSLALGRVAAGEGDDPLRVSLGLAYPVLDILLVSLVVGLRFRGRDGNRAAVHTAMVGLAVTVVCDALFTSPEVHSTYHSGELLDAGWFAGSVLLAWAPWSAPRRSEREQHPSAGGPRRRVSTLFSAVTPYVAAAVCTSGILYTTLGGRPLDRVVLTAASTVGLALILRQAIVLLDNLKLAQALAAKEAHFRSLVQGSSDVIMIAGPNAVLSYVSPAAIGVYGRDPEELVGGNLLNLVHPEDVDRMLAEVRRLLGEPPEQAGEPSARVECRIRSGGGEWLHVESTVNRHRDGLILNCRDVTERVRLQAQLQHNAFHDPLTDLPNRALFTQRVRAALTEPSVPTQPCPQDGTQSVYAEAARDCEGTVAVLFLDLDGFKAVNDTAGHQVGDELLVQAARRLQGAVRSGDTVARFGGDEFAALVRGRLGRTQVQELAERVRAALSEPYWIGGAELGVAASIGIAFAARGPQADPKAAGDELMRNADLAMYQAKSQGKGRVVLYSGDMRAELDRRSELEGRLRVAVREGGFTLLHQPVVDLRNGVVAAVEAQARWRSAQGLLLTPAEFLRATEHGDAATRFARWLLQEAVGAAATRQAVALPQAVPVPVSVRLTAERLCAPGMYETVVAVLRESGLPAGLLVLELARTGQDSGADELGRRLAALRRLGVSTAVAGFGAGSGSLGALARLPFDALKLDRTLVQDLADSAVTRALAGHAVRLARELGLVAQAEGVDHARQVAALQELGCRHGQGLAFAQPLDEYRLRRALARRVYPLPRPLGTLSGRRAYLAADTRSGGRPDLSQPRPTHHHAAPDLPERRAPAGPLVGPHGETSVPPA
>NZ_CP025394.1|WP_104818405.1|5931923_5933777_+|acetolactate-synthase-large-subunit
MTEHAATPRRGDNPAAHAPGSTTVVETMTGAQSLIRSLEAVGADTVFGIPGGAILPAYDPLMDSVKVRHILVRHEQGAGHAATGYAQATGRVGVCMATSGPGATNLVTPIADAYMDSVPIVAITGQVASKAIGTDAFQEADICGITMPITKHNFLVTDAAEIPRVIAEAFHIAGTGRPGPVLVDIAKDALQATTTFRWPVETNLPGYRPVTKPHAKQIREAAKMLVSAKKPVLYVGGGVLKAQASAELRILAELTGAPVVTTLMALGVFPDSHPQHLGMPGMHGSVPAVTALQKSDLLFTLGARFDDRVTGKLDSFAPYAKVVHADIDPAEIGKNRPADVPIVGDAREVLADLIVAVQAEFDAGHKADYADWWVKLNEWKKTFPVGYEPAPEGELSPQQVIERIGQKVGSDAIYAAGVGQHQMWASQFINYEKPATWLNSGGAGTMGYAVPAAMGAKAGKPDTVVWAIDGDGCFQMTNQELVTCALNNIPIKVAVINNGSLGMVRQWQTLFYNQRYSNTVLHSGPEHDGKEPPAQGTRIPDFVMLSEAMGCVGLRCERPEDLDAVIEQAMAINDRPVVIDFIVHQDAMVWPMVAAGTSNDEILAARDVRPDFGDDLD
>NZ_CP025394.1|WP_104818406.1|5933813_5934338_+|acetolactate-synthase-small-subunit
MSKHTLSVLVENKPGVLARIAALFSRRGFNIDSLAVGPTEHPDISRMTIVVNVEDLPLEQVTKQLNKLVNVIKIVELDQSAAIQRELVLVKVRADAETRSQVVEIVQLFRAKTVDVSPDAVTIEATGSSDKLEAMLKMLEPYGIKELVQSGLVAIGRGARSITDRSLRALDRSA
>NZ_CP025394.1|WP_104818407.1|5934442_5935441_+|ketol-acid-reductoisomerase
MAELFYEDDADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLLEGSKSRAKAEEAGLKVTDPATAAAEADVIMILVPDPIQADVYKESIEPNLKAGDALFFGHGLNIRFGFIQPPADVDVCMVAPKGPGHLVRRQYQEGRGVPCIVAVEQDATGKGFELALSYAKGIGGTKAGVIKTTFTEETETDLFGEQAVLCGGTAALVKAGFETLVEAGYQPEIAYFECLHELKLIVDLMYEGGLEKMRWSVSETAEWGDYVTGPRIITADTKAEMKKVLAEIQDGTFANTWIAEYKAGLPKYNAYKNADSEHLLETTGKKLRKLMSWVDEEA
>NZ_CP025394.1|WP_104818408.1|5935663_5937244_+|phosphoglycerate-dehydrogenase
MSKSVVLIAEELSPATVDALGPDFEIRQCNGADRTELLTAIADVDAILIRSATKVDAEALAAAKKLKVVARAGVGLDNVDVSAATKAGVMVVNAPTSNIVTAAELACGLLISVARNIAPANAALKQGEWKRNKYTGVELSEKTLGVVGLGRIGVLVAQRMSAFGMKIVAYDPYIQAARAAQMGVKLVTLEELLEVADFITVHLPKTPETIGLIGDEALHKVKPTVRIVNAARGGIVDEAALASALRDGRVAGAGLDVYAKEPCTDSPLFGFDNVVATPHLGASTDEAQEKAGIAVAKSVRLALAGELVPDAVNVQGGVIAEDVKPGLPLAEKLGRIFTALAAEVAVRLDVEVRGEITQHDVKVLELSALKGVFEDVVAETVSYVNAPLFAQERGVEVRLTTSSESPEHKNVVTVRGTLADGGEVAVSGTLSGPKQTQKIVGVDAFEVDVALTDHMAFFKYEDRPGVVGTLGRILGDAGINIAGMQVARDGGLALASITVDTEVSQEVLAEIASAIGARFSRSVNLG
>NZ_CP025394.1|WP_158702358.1|5937501_5937657_+|hypothetical-protein
MPTVADRHAATPATQTRVPRRRHARTECDAHAAQALQRALDRRDNGGATGH
>NZ_CP025394.1|WP_104818409.1|5937679_5938585_-|LysR-family-transcriptional-regulator
MKISQCSAFVAIADTGSFTNAAKTLRVSQSAVSHSIAGLEATLGVALMQRDRGGVRLTEAGRRVLAHARAVLLHAEQMRRVATGSAAESAGVLRIGAAGDVAARLLPRLGAEYRAKMPGGELTLRAGGDRQISDWLRSGAVDLGILGSPRAELPTLPLLREELVLVLPGGHPLAGAAGLGVRQLLAEKFVLPVDGVEPALRTAFRALGREPAVSLRLPDLDELLGLVGRGHGVTVVSAPALPGELPGTLRAVPFAPRLHRSLVLGLRPSVRHTPAVTAFLAAARGLPTAGRMLTAAGPARR
>NZ_CP025394.1|WP_104818410.1|5939045_5939723_+|response-regulator-transcription-factor
MAPQLGEWRVGPPETDPRVLLADADPLSRHVLTDVLGRSGQLRSVTGVDLAAPLRRWPLAEVDVAVLNLAEGQERGRAVRELTAQGVKVLVVAGGWTKARLAAALAAGAAGCLARDARVGRLVPAVRAVAAGHAVLSPELLALDHRPPATEPAPTEEQARQLLRTLTEREHEVLVLLAGGSSTPEVAAALGVAPATVKSHITHALGKLGARNRLEAVLLVQRESA
>NZ_CP025394.1|WP_104818412.1|5943154_5943658_-|GtrA-family-protein
MKPQFWQFVRFGLVGGVNTANSFLLFWLFDHVLPYFAAFTLSFALAMVGSFFLNCHFTYRTKPTWKKFALFPIPNVTNYLVQSGGLVALVGWWHLDHLLALLLVSLVAIPVTFVLSKIILIGRSPQVEDLGAGAVGVEVVEQEQPGRVALGAADLQHGARAGRGEQG

Crispr_ID: NZ_CP025394_13

• CRISPR_ID: NZ_CP025394_13
• CRISPR_location: 6254579-6254665
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_13

Consensus_repeat	Method
GGCGGCGGGTACCCGTACCCGGCCGGC	CRISPRCasFinder

spacers of NZ_CP025394_13

>13.1|6254606|33|NZ_CP025394|CRISPRCasFinder
GGGGCGGGGGCGGCCGGCGGCGGGAAGGGCGCG

CRISPR arrays and Neighbor proteins around NZ_CP025394_13

CRISPR arrays

The CRISPR arrays of NZ_CP025394_13

>merge|NZ_CP025394|13|6254579-6254665|CRISPRCasFinder
GGCGGCGGGTACCCGTACCCGGCCGGCGGGGCGGGGGCGGCCGGCGGCGGGAAGGGCGCGGGCGGCGGGTAGCCGTACCCGGCCGGC

>NZ_CP025394|13|12|6254579-6254665|CRISPRCasFinder
GGCGGCGGGTACCCGTACCCGGCCGGC	GGGGCGGGGGCGGCCGGCGGCGGGAAGGGCGCG
GGCGGCGGGTAGCCGTACCCGGCCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_158702365.1|6246258_6247104_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|239942
NZ_CP025394.1|WP_104818610.1|6249786_6250245_+|acyl-CoA-thioesterase	unknown	unknown	gnl|CDD|223894
NZ_CP025394.1|WP_104818607.1|6243945_6244509_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NZ_CP025394.1|WP_104818618.1|6257550_6260127_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|319004
NZ_CP025394.1|WP_104818616.1|6255130_6256438_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238119
NZ_CP025394.1|WP_104818624.1|6266374_6267445_-|ATPase	unknown	unknown	gnl|CDD|225518
NZ_CP025394.1|WP_104818623.1|6264688_6265282_-|cysteine-hydrolase	unknown	unknown	gnl|CDD|238496
NZ_CP025394.1|WP_104821151.1|6245013_6245361_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379409
NZ_CP025394.1|WP_104821152.1|6265362_6266325_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|181818
NZ_CP025394.1|WP_104818619.1|6260133_6261423_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818609.1|6247958_6249623_+|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NZ_CP025394.1|WP_104818622.1|6264104_6264680_+|nucleoside-phosphorylase	unknown	unknown	gnl|CDD|235538
NZ_CP025394.1|WP_104818606.1|6243390_6243810_-|RidA-family-protein	unknown	unknown	gnl|CDD|223329
NZ_CP025394.1|WP_104818614.1|6252907_6253825_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NZ_CP025394.1|WP_158702366.1|6262422_6263823_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818617.1|6256519_6257545_-|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|223704
NZ_CP025394.1|WP_104818612.1|6251261_6251666_-|globin	unknown	unknown	gnl|CDD|381280
NZ_CP025394.1|WP_104818611.1|6250423_6251134_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104818613.1|6251768_6252911_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NZ_CP025394.1|WP_104818620.1|6261475_6262408_-|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_158702365.1|6246258_6247104_+|single-stranded-DNA-binding-protein	gnl|CDD|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	1.76518e-27
NZ_CP025394.1|WP_104818610.1|6249786_6250245_+|acyl-CoA-thioesterase	gnl|CDD|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	8.68306e-31
NZ_CP025394.1|WP_104818607.1|6243945_6244509_-|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	9.77855e-25
NZ_CP025394.1|WP_104818618.1|6257550_6260127_-|serine/threonine-protein-kinase	gnl|CDD|319004	pfam16918, PknG_TPR, Protein kinase G tetratricopeptide repeat. This domain is found at the C-terminus of protein kinase G and contains a tetratricopeptide repeat (TPR).	1.77377e-87
NZ_CP025394.1|WP_104818616.1|6255130_6256438_-|VWA-domain-containing-protein	gnl|CDD|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	1.27978e-15
NZ_CP025394.1|WP_104818624.1|6266374_6267445_-|ATPase	gnl|CDD|225518	COG2971, COG2971, Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism].	6.51757e-25
NZ_CP025394.1|WP_104818623.1|6264688_6265282_-|cysteine-hydrolase	gnl|CDD|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	1.04096e-46
NZ_CP025394.1|WP_104821151.1|6245013_6245361_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl|CDD|379409	pfam13977, TetR_C_6, BetI-type transcriptional repressor, C-terminal. This family comprises the C-terminal portion of proteins that belong to the TetR family of transcriptional regulators. The C-terminus represents the regulatory region, and does not include the DNA binding helix-turn-helix domain. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. One of the target proteins is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	1.23035e-10
NZ_CP025394.1|WP_104821152.1|6265362_6266325_+|helix-turn-helix-domain-containing-protein	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	5.54358e-94
NZ_CP025394.1|WP_104818609.1|6247958_6249623_+|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP025394.1|WP_104818622.1|6264104_6264680_+|nucleoside-phosphorylase	gnl|CDD|235538	PRK05634, PRK05634, nucleosidase; Provisional.	8.94501e-71
NZ_CP025394.1|WP_104818606.1|6243390_6243810_-|RidA-family-protein	gnl|CDD|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	9.91998e-17
NZ_CP025394.1|WP_104818614.1|6252907_6253825_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.52625e-99
NZ_CP025394.1|WP_104818617.1|6256519_6257545_-|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.78372e-37
NZ_CP025394.1|WP_104818612.1|6251261_6251666_-|globin	gnl|CDD|381280	cd14771, TrHb2_Mt-trHbO-like_O, Truncated hemoglobins, group 2 (O); Mycobacterium tuberculosis hemoglobin O like. The M- and S families exhibit the canonical secondary structure of hemoglobins, a 3-over-3 alpha-helical sandwich structure (3/3 Mb-fold), built by eight alpha-helical segments. Truncated hemoglobins (TrHbs, 2/2Hb, or 2/2 globins) or the T family globins adopt a 2-on-2 alpha-helical sandwich structure, resulting from extensive and complex modifications of the canonical 3-on-3 alpha-helical sandwich that are distributed throughout the whole protein molecule. TrHbs are classified into three main groups based on their structural properties and named after Mycobacterium sp. genes glbN, glbO, and glbP: TrHb1s (N), TrHb2s (O) and TrHb3s (P). This group includes a Mycobacterium tuberculosis TrHb2, Mt-trHbO, encoded by the Mycobacterium tuberculosis glbO gene, which is expressed throughout the Mycobacterium growth phase. It also includes a TrHb2 from the thermophilic Thermobifida fusca ( Tf-trHb) which has a high thermostability and at the optimal growth temperature for Thermobifida fusca (between 55 and 60 degrees C ), it is capable of efficient O2 binding and release. Tf-trHb shares a relatively slow rate of oxygen binding with Mt-trHbO.	2.36614e-65
NZ_CP025394.1|WP_104818613.1|6251768_6252911_-|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	7.18131e-25
NZ_CP025394.1|WP_104818620.1|6261475_6262408_-|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.79561e-82

Protein sequences

>NZ_CP025394.1|WP_104818614.1|6252907_6253825_-|ABC-transporter-ATP-binding-protein
MTAAISADGIRKRYGDVQAVDGVSLTVEPGEFYGILGPNGAGKTTTLEILEGIREPDEGRIELLGMAPWPRNPKLLPRIGVQFQASAFFVKLTARETIRTFASFYGVGPKRADAMLERVGLTDSASVLTDKMSGGQAQRLSIACALAHDPELVFLDEPTTGLDPQARRNLWDLLRDINAEGRTVVLTTHYLDEAEVLCDRVSVMDHGKVLKTGAPQALVREIDDTVRVSVESGLLTTEAADSLLTAAGADFANLEDNGVSLALSTRAPGPVLSVLADNNALRGLEVRGATLEDVFLQLTGREYRA
>NZ_CP025394.1|WP_104818613.1|6251768_6252911_-|ABC-transporter-permease
MSAATESPATGPKGSAPRDAESSERASSFVSLSRVMMLGFVRDRTALFFTLAMPLMFLLLFGALFKSAGASHVKFGEVGQVQVLDGLPADARAKLDKSIAVTKYTDADAALAKLRKGDLDGVIEQDADGRITVRYSASDQVKSGVVQTIAGDLVNGANLAATGQAPKYALSLAQVEDESLKPIQYLTPGLLGWAIATGAVFGTSFTLVNWRKKRVLRRLRLAPVSIGAVVAARVTVSVAVSLAQTAIFLVVATTPFFGLKLTGNWPLVIPVVVCSTIAFMSIGLLTGSIAKSEEAANGINQVIVLPMSFLAGAFFPLDGAPTWLQDVSRVLPLRYLVTSAQSVLTKGGGVMDILPSMGGLLLFAAVLTAISWKFFRWDDA
>NZ_CP025394.1|WP_104818612.1|6251261_6251666_-|globin
MTEIRRGTLPEETFYDAVGGEPTFRRLVHRFYQGVAEDELLRPMYPEEDLGPAEERLALFLMQYWGGPRTYSDHRGHPRLRMRHAPFRVDQAAHDAWLKHMRVAVDELRLPAEAEEQLWDYLTYAAASMVNTAG
>NZ_CP025394.1|WP_104818611.1|6250423_6251134_+|hypothetical-protein
MTTNTSLPLADSGEAADLVAFLTRLLRFDRAAAVRLQAVAGGGGADPVGADGVVAVFGRLPLGSTGALAIRTARLARFDSAVDLTVSAGQLLEGVDTEAAELRLPAPVTGPSWAGLLPPRAGWELVGEPAALAVAPEVTAAVREFRERSEAVPEHHRTRTVLDGLADEIWARPLAAQPELPLRAAHAAYVIGFLTPQSTLTVHRAGAWRRLSCPAGSIAVRSTAALGAGLGLTPLR
>NZ_CP025394.1|WP_104818610.1|6249786_6250245_+|acyl-CoA-thioesterase
MARHIYACPLRWSDMDAFGHVNNVVFLRYLEEARIDFMFTQAAAAGAGEFAGGSVVARHEIDYKRPLVHRPAPVTIETWVTKIGGASLTVSYEIKDTAEDGTETVYVRASTVVVPYDLAEGRPRRISAVEREFLGRFMDAAEDAVEPQAVAA
>NZ_CP025394.1|WP_104818609.1|6247958_6249623_+|energy-dependent-translational-throttle-protein-EttA
MAEYIYTMRKVRKAHGDKVILDDVFLSFLPGAKIGVVGPNGAGKSTVLKMMAGLDQPSNGEAFLSPGYTVGMLLQEPPLDESKTVLENVQDGVKETKGKLDRFNEIAELMATDYSDALLEEMGKLQEDLDHAEAWDLDAQLEQAMDALGCPPGDWPVTSLSGGERRRVALCKLLLEAPDLLLLDEPTNHLDAESVNWLEQHLAKYKGTVVAVTHDRYFLDHVAEWILELDRGRAYPYEGNYSTYLETKQTRLKVEGQKDAKRAKRLKEELEWVRSNAKGRQAKSKARLARYEEMAAEADKMRKLDFEEIQIPPGPRLGSIVVEVDKLNKAFGEKVLIEDLSFTLPRNGIVGVIGPNGAGKTTLFKMLQDLETPDSGTVKVGETVKISYVDQSRANIDPKKTLWEVVSDGLDWINVGQVEMPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKQGGNLLLLDEPTNDLDVETLSSLENALLEFPGCAVVISHDRWFLDRVATHILAYEGESKWFWFEGNFESYEKNKVDRLGADAARPHRATYKKLTRG
>NZ_CP025394.1|WP_158702365.1|6246258_6247104_+|single-stranded-DNA-binding-protein
MNETSVTMVGNVASGVSYKQTPAGVPVANFRMATTERRFDRSAGDWIDGETIWVTVVAWRWLATNVVSSLNKGDPVVVSGRLRVREWGEEEKKHTAIEIDARVVGHDLGRGTSAFRWAVQARPELVAGRAGPEEQPVLAASVSTAASVPVPAAAAVGVPPGEVVPPPVVAVPAPAARAAPLAAAPAAPAPAPLPGGAEPVEDALPAWIVAAVEGRRAEGVVIGGSGISSGISSGAGDALGGGTDPEVRAAGAVVQAAEEVIGAAREDADGDIACTDRVPVG
>NZ_CP025394.1|WP_104821151.1|6245013_6245361_+|TetR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MLRAVLLDVLPLEPESAASNRIWVGSWDTALADPELAAEHAERYRRSRARMAVHVAAAQAAGELPDGVPAADLAAAAQGFVLGLVVQALFAPAEYPAERQVALLDGYLDGLRARR
>NZ_CP025394.1|WP_104818607.1|6243945_6244509_-|GNAT-family-N-acetyltransferase
MYAIPLAPGAELRPLEPWQAAEFLAHIDRGRATIDPWIPWASRSTDLDSARATLQGYADRQATDTGRIYGIWLEGTLVGGVMFVSFNAPSGNCEIGVWTEPAGEGKGLISAAVRHLIDYAFLERGLHRIEWWNTTDNLRSRAVAERMGMHLDGVLREYYLHNGVRHDEELWSLLRHEWPLKTADAQG
>NZ_CP025394.1|WP_104818606.1|6243390_6243810_-|RidA-family-protein
MARHSVVPALFPPPGYAHTALVAAGEQLAFLAGGVPLDPAGALVGPGDHVAQARQVLANLAVALAHVGSGLEHVVASTVYVVADAPGPLSEVWEVVLESGLSAGPHTSTLLGVSTLGYTGQLVEITVTAVVPSTAAVEG
>NZ_CP025394.1|WP_104818616.1|6255130_6256438_-|VWA-domain-containing-protein
MPHPSFAVDIFQNEYLAVGAREVNAIVTVTASGAALPAQRQGTPAADSAVVLMIDCSGSMDYPATKLRAAREATAAAIDTLRDGVAFAVVAGTHEAREVFPGGGGLAVSSPATRGQAKESLRKLTASGGTAIGTWLTLADRLFRSRPQAGLRHAILLTDGKNEHETPEELERVLAEVSGRFTADCRGVGTKWEVKELRKIATALLGTADIVAEPDGLAEDFRAMTAGALNKAVADVRLRVWTPANAVVKYVKQVAPEVVDLTGRRSEAGPRAGDYPTGSWGEESRDYHVCVEVPAAAVGSEMLAARISLVLAGPDGSPEVLSQGLVRAVWTDDLASSTRISPQVAHYTGQAELAASIQEGLEAHRAGDLDRATAKLGAAVRIAHATGNDGTFKLLQKVVDVVDPKEGTVRFRSHVSAADSMTLETRSTKTVRVKK
>NZ_CP025394.1|WP_104818617.1|6256519_6257545_-|protein-phosphatase-2C-domain-containing-protein
MPQQTVCPSCAEPWDEEDAFCGACGRSLRPPGPAAVPCVHCGAAEVAADGYCEACGGSQPKPRDHQEQALTGADGVATVAGVSDRGRRHHRNEDAFTLASAILPGGEPAVFAVVCDGVSSSARPDEASEAAVTAAATALRGSLARGAEPGSAMRAAIHEAAEAVTALAHDGKTDGRQSAGRSLNAPACTYVSAVSTAGAVTIGWVGDTRAYWVPDDRAGAEPYRLTEDDSWAARVVAAGLVGEAEAYADPRAHAITGWLGADAEDLEPHTVAFTPHVPGVLLICSDGLWNYAEAATDLAEVVRTDARAEPLAAARELVEYALAAGGHDNITVAVLPIDPAG
>NZ_CP025394.1|WP_104818618.1|6257550_6260127_-|serine/threonine-protein-kinase
MPDDPCAQPACPGTIDPDGYCTECGLAAARPTGTASGTLSGTASGTLSGTASGIGTGLGVGTGRPSGAAGTGTASGPSTGVGSGAGGPGDPCGRDCGGTIDPDGYCDECGLAPLALAPATTGSAVSTGTEPYTPSGRSAASRSSRSGRSGRSGRSGRSRSGRTGSGSGPSVRVPASRSTPTARRGNLGAGLVTVPPVPPADPAAAVLVDPSVPERKRYCSSCELPVGREKNGRPGRPDGFCTKCGTPYSFTPKLRAGDLVGGQYAVLGCLAHGGLGWIYLAQDRRVSDRWVVLKGLLDTGDRDALAVAIAERRFLAEVDHPNIVRIINFVEYPDPRTGTVDGYIVMEYVGGKSLKDIASERRTPDGLRDPLPVEQAIAYALEALPALGYLHARGLVYCDFKIDNVIQSEDSLKIIDMGAVRRFDDDGPIYGTVGYQAPEIAAEGPSPASDLYTVARTLAVLTFDFQGYNSTYRYELPAQAEVPVLAEYESYYRFLVRATDPDPARRFGSAEEMADQLTGVLREVLSRRDGQARPAVSKLFGPELRVVDTELTGAPLDPAAATTALPLPRVDTDDPNAGLLAGLAGPPAEVLTALAAALTGAAGPSVELSLRALRARLELGDPAGAADGLAELEREHPEDWRVVWYRGLVALAAGRAEEAAESFDAVYDAFPGEPAPKLALAVCAELLGDWAEAAECYRLVAAVDRGYVGAAFGLARVRLADGDRAGAVAALEAVPESSAHYTAARIGAVRARLRGRPGSDPLGPDLTRCSAQLAALALDARRREELAVEVLDTALAWVLADPAQRSGTVEVLGHRGGERELRFALEQSYRVLARLSDRAEYRIEMVERANRARPRTWV
>NZ_CP025394.1|WP_104818619.1|6260133_6261423_-|hypothetical-protein
MSREEVDRALARLSAERDAVEAALLTLQDHPGRRLLDGAALTGRTQERWALAEQGLGLLWSLFDRYSEALASARAVRSRRAKPGGAELAELSELLGGPAVNVPGSRLPGPDGPAPARLVEQVSLAELVERMNGWYATVLEVVGAADAVWSALPTRIELLLAELGRVRMLAGSVGVRPGAHPMADDLAELEGELTALRAEVRADPLALWRPARVPEQGGGLGRPAAGGAVDTERFDRAGRALDGIRVELEGLLRLRDEAHERLLSVGDLVQRADATLAEARRARGEVLAKIAATEVPAVPGPASVLRERIALAVELQQSGQWHRLAPLLDTLEDAAAKELSRARHSLTEVAAPLAARAELRGRLEAYKAMAARLDVAEDPEVVERFEKARWLLWSAPCDLRAAADAVARFQQALRPAATARPDTQDEQGA
>NZ_CP025394.1|WP_104818620.1|6261475_6262408_-|glutamate-ABC-transporter-substrate-binding-protein
MRGVRNKALVAVVAAAAGLLGAGSSQGAPTGVVTAAPAAAPAEVPAAAAGCDTRSSLPASRDESGAAVQRIKKAGTLVVGVDQNSYHWGYRDPQTGQIEGFDIDLAHAVAKALLGDPAKVTFKTVPTAQRIQAIQEHKVDLIARTMTITCDRLQQVAFSVPYFSSGQRLVVPRSAHVDKLEDGVRGKRVCAAKQSSSQTELQQNPRGAAAVTLVDNQLDCLVLMQLGQVDATLTDTTLAAAQTAQDPTVEMAGEQIVPAYMGIAMNQKDTDLVARVNQVLADYRAGGGWQASYQRWLAASMGADPAQYLP
>NZ_CP025394.1|WP_158702366.1|6262422_6263823_-|hypothetical-protein
MPAQAGAAAQTGPATPAVVTPPAAPYRAPWRRVGLRLRRATRTAPGRLRLAVLLLLGLLLVSGAATAWQAVSRGLATDRVVSHSEPLSQDAAEIYRSLADADTTAAANFLLAGNATAAGRQRYQDDLAKAADLLARAAARTDTSSDAQHAIATLNQQLPQYSALVATAVANDRQGLPLGGAYLRYASGLMQGSMLGSAKQLVQAEGGQLDADYRAALGFPVVAAVLGVLVLAALVRCQVLLLRRTNRVFNLGLLGATAAVLVTLGWLATAATTAQSGLDRSRAHAALPLRQLDQLRLTALQARTAEYLDLVARGASDTYTTQWDQDSAALAGKPGAGGSAPAGALLDLAGRNAPAGVDGELAAAAAAFRSWDTAHKSAADANHNGDYDTALRTTVDATAASSSATAFATMDTHLARAATIEQAEFRAAAQGVGGWWYALAGGAAVLTVLGAAGVVLGLGRRLAEYR
>NZ_CP025394.1|WP_104818622.1|6264104_6264680_+|nucleoside-phosphorylase
MRLLGTISPTRPLLVVAVEEEAAHLGDALPVLLTGIGKVNAASALATVLARGDRPAGIVNLGTAGALRPGLAGTHEIATVIQHDLDTAVLHQLTGRTYGAPVTLHEGPGLTLATGDLFVSDEDARERLARSADLVDMEGYAVATVAQRAGVPVRLVKHVSDEAGAGADRTWREAVDGCAKLLAEWVADADL
>NZ_CP025394.1|WP_104818623.1|6264688_6265282_-|cysteine-hydrolase
MTNTSAFDAPLQLAEDAVLIVIDVQQGFEDRAYFGPRDNPSADERMASVIAAWQRTGRPIVTVQHRSASGPLAPGTPGYELKPYVAAVAADLHVTKTVNSSFYGTPDLHEWLQRRGATQLVTIGILTNVCNETTARMGGNLGYDVVFPIDAMHTVDMATPDGTVVPAAELARATAAALHSMRFAKVVTTEALLAAAA
>NZ_CP025394.1|WP_104821152.1|6265362_6266325_+|helix-turn-helix-domain-containing-protein
MGCLVFDGVRAFDYAVINEVWAGSEFDLRVCGPVGARVRLGGGLELAPAHGLDGLLGCDLVVVPGVADPAAARPEPVLAALRAARARGVPVAGLCAGAFVLAEAGLLAGRTATTHWRLAAELAARHPTVTVDPEVLFTGDGEVWTSAGVAAGIDLCLHLVRAAHGQSAAAGIARSMVTAPFRAGGQAQFIPSPVPATQDRADPLAEARSAVLDALDKPWSVGELARIALMSERTFARRFTEAVGVPPLRWLLEQRVLAAQRLLEETELGVGQIAARCGFGTAVAFRAAFVKRVGVVPSDYRRTFGRQGRGELREVGRSGQ
>NZ_CP025394.1|WP_104818624.1|6266374_6267445_-|ATPase
MDHRPTDEQLPGVLAIDAGNSKTDVALVSAAGEVLATARGGGFQPQRVGADTAVAGLTPLVEAVAAQASLTLGGRPLTTHVSACLANADLPVEEQALQTAVAARPWGVSSSVVNDTFGLLRAGTEGPLGVAVVCGAGINCVGLLPDGRTARFPALGALTGDWGGGHGLATESLWHAHRAEDGRGRPTGLAPAIAAHFGLPTAAAVAEAIHLGRIADTRLHELVPVLFHEAAAGDAVALELVDRQADEITRLAVVALTRLDLLDTPAPVVFGGGVLSSRHPLLIDNIQTRLAAAAPLAAPRIVVAPPVLGAALLGLDALGASPAAQERLRLHYESAAPSRGAGNGAASPNQARSLTV

Crispr_ID: NZ_CP025394_14

• CRISPR_ID: NZ_CP025394_14
• CRISPR_location: 6325007-6325112
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_14

Consensus_repeat	Method
CTTCCGACTTCGCGCAGTTCCCCGCGCCCCT	CRISPRCasFinder

spacers of NZ_CP025394_14

>14.1|6325038|44|NZ_CP025394|CRISPRCasFinder
GGATAGTGCAACCGGATCGAAGCGGGAGCCGATCAGGTCCGCTT

CRISPR arrays and Neighbor proteins around NZ_CP025394_14

CRISPR arrays

The CRISPR arrays of NZ_CP025394_14

>merge|NZ_CP025394|14|6325007-6325112|CRISPRCasFinder
CTTCCGACTTCGCGCAGTTCCCCGCGCCCCTGGATAGTGCAACCGGATCGAAGCGGGAGCCGATCAGGTCCGCTTCTTCCGACCTCGCGCAGTTCCCCGCGCCCCT

>NZ_CP025394|14|13|6325007-6325112|CRISPRCasFinder
CTTCCGACTTCGCGCAGTTCCCCGCGCCCCT	GGATAGTGCAACCGGATCGAAGCGGGAGCCGATCAGGTCCGCTT
CTTCCGACCTCGCGCAGTTCCCCGCGCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104821157.1|6331641_6332517_-|RNA-polymerase-sigma-70-factor	unknown	unknown	gnl|CDD|132002
NZ_CP025394.1|WP_104818653.1|6315281_6316190_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP025394.1|WP_104818662.1|6326589_6327297_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP025394.1|WP_104818669.1|6334575_6335313_+|chlorite-dismutase-family-protein	unknown	unknown	gnl|CDD|377705
NZ_CP025394.1|WP_104818654.1|6316186_6316954_+|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224051
NZ_CP025394.1|WP_104818655.1|6317124_6318147_+|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|270225
NZ_CP025394.1|WP_104818652.1|6313415_6314633_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274819
NZ_CP025394.1|WP_158702369.1|6335339_6336335_-|glycosyltransferase	unknown	unknown	gnl|CDD|366154
NZ_CP025394.1|WP_104818663.1|6327694_6328345_-|DUF3000-domain-containing-protein	unknown	unknown	gnl|CDD|378665
NZ_CP025394.1|WP_104818660.1|6323587_6324805_-|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|273881
NZ_CP025394.1|WP_104818658.1|6319918_6320860_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270225
NZ_CP025394.1|WP_104818656.1|6318173_6319022_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|117022
NZ_CP025394.1|WP_104818664.1|6328571_6329657_+|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
NZ_CP025394.1|WP_104818659.1|6320867_6321356_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|223532
NZ_CP025394.1|WP_104818657.1|6319018_6319897_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP025394.1|WP_104818667.1|6332560_6333145_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NZ_CP025394.1|WP_104818668.1|6333178_6334579_+|protoporphyrinogen-oxidase	unknown	unknown	gnl|CDD|237009
NZ_CP025394.1|WP_104818666.1|6330786_6331563_-|NAD(P)H-binding-protein	unknown	unknown	gnl|CDD|187554
NZ_CP025394.1|WP_104821156.1|6321464_6323576_-|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|236864
NZ_CP025394.1|WP_158702368.1|6329666_6330686_-|DUF4349-domain-containing-protein	unknown	unknown	gnl|CDD|379526

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104821157.1|6331641_6332517_-|RNA-polymerase-sigma-70-factor	gnl|CDD|132002	TIGR02957, putative_sigma_factor, RNA polymerase sigma-70 factor, TIGR02957 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.	8.24491e-110
NZ_CP025394.1|WP_104818653.1|6315281_6316190_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	6.50639e-65
NZ_CP025394.1|WP_104818662.1|6326589_6327297_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.45242e-23
NZ_CP025394.1|WP_104818669.1|6334575_6335313_+|chlorite-dismutase-family-protein	gnl|CDD|377705	pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyzes the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.	9.91827e-104
NZ_CP025394.1|WP_104818654.1|6316186_6316954_+|amino-acid-ABC-transporter-ATP-binding-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.18721e-142
NZ_CP025394.1|WP_104818655.1|6317124_6318147_+|transporter-substrate-binding-domain-containing-protein	gnl|CDD|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.20802e-58
NZ_CP025394.1|WP_104818652.1|6313415_6314633_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	1.01703e-74
NZ_CP025394.1|WP_158702369.1|6335339_6336335_-|glycosyltransferase	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	2.68663e-16
NZ_CP025394.1|WP_104818663.1|6327694_6328345_-|DUF3000-domain-containing-protein	gnl|CDD|378665	pfam11452, DUF3000, Protein of unknown function (DUF3000). This is a bacterial family of uncharacterized proteins.	2.39802e-81
NZ_CP025394.1|WP_104818660.1|6323587_6324805_-|acetyl-CoA-C-acyltransferase	gnl|CDD|273881	TIGR01930, 3-ketoacyl-CoA_thiolase, acetyl-CoA acetyltransferases. This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other].	2.50306e-156
NZ_CP025394.1|WP_104818658.1|6319918_6320860_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.82688e-59
NZ_CP025394.1|WP_104818656.1|6318173_6319022_+|GNAT-family-N-acetyltransferase	gnl|CDD|117022	pfam08445, FR47, FR47-like protein. The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.	2.12008e-26
NZ_CP025394.1|WP_104818664.1|6328571_6329657_+|uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_CP025394.1|WP_104818659.1|6320867_6321356_-|GNAT-family-N-acetyltransferase	gnl|CDD|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	4.74809e-12
NZ_CP025394.1|WP_104818657.1|6319018_6319897_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.69294e-65
NZ_CP025394.1|WP_104818667.1|6332560_6333145_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	3.07029e-22
NZ_CP025394.1|WP_104818668.1|6333178_6334579_+|protoporphyrinogen-oxidase	gnl|CDD|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	1.68225e-141
NZ_CP025394.1|WP_104818666.1|6330786_6331563_-|NAD(P)H-binding-protein	gnl|CDD|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.05696e-24
NZ_CP025394.1|WP_104821156.1|6321464_6323576_-|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	1.81634e-112
NZ_CP025394.1|WP_158702368.1|6329666_6330686_-|DUF4349-domain-containing-protein	gnl|CDD|379526	pfam14257, DUF4349, Domain of unknown function (DUF4349). This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important.	2.60538e-56

Protein sequences

>NZ_CP025394.1|WP_104818660.1|6323587_6324805_-|acetyl-CoA-C-acyltransferase
MPRTARDVVFVDGVRTPFGKAGPKGIYHETRADDLVVKCIRELVRRNPNLPVERIDEVAIAATTQIGDQGLTIGRTAALLAGLPKSVPGYAIDRMCAGALTAVTTTAGGIAFGAYDIVVAGGVEHMGRHPMGEGVDPNPRFVSEKLVDESALFMGMTAENLHDRFPHITKERCDAYAVRSQEKAAKAYANGDIQPDLVPISIRNTNPEAGETGWGLATSDEPMRPGTTMESLAGLKTPFRPHGNITAGNSAGLNDGATASLLAAEDVAEELGLPVKMRLVSYAFVGVEPEVMGIGPVPATEKALAKAGLTIDDIQAFEINEAFAVQVLAMLDHFGIADDDERVNPYGGAIAFGHPLASSGVRLMNQLARRFEQRPDVRYGLTAMCIGFGMGATVIWENPHFEGTK
>NZ_CP025394.1|WP_104821156.1|6321464_6323576_-|enoyl-CoA-hydratase/isomerase-family-protein
MLKRAAELFPGEVVTTAHVRHLDLPLQAGKLAMITLDNGFDHTKPTTFGPGSLAKLSEALDQVEAEAAEGKIVAVAITGKPFIFAVGADLKGVEVLKEHSDALAIGKGGHDVFKRIAALPVPTFAFYNGAAMGGGVEVGLHATYRTVSSGVPAFSLPEVFLGLVPGWGGCTILPNLIGPAKAVKVIIENSMSQNKQLKGKEVFELGIADAIFEPADFLEQSILWAAKVLKGEVTVEREEHDRGKAWDDAVTWGRWVADAKVHGAAPAAYKALDIIQQVKDGDLQAGFDAEDAALAELIMSGELRSGIYAFNLVQRRAKRPFGAPDKSLARPVSKVGVVGAGLMASQLALLFARRMEIPVVLTDIDQERIDKGVGYVHGEIDKLLAKGRIGNDKANKLKGLVSGHLDKAVAFGDADFVIEAVFEEMGVKQSVLAELEAVVSPTTILATNTSSLSVSEMASKLEHPERVVGFHFFNPVAILPLLEIVRAEKTDDGSLATAFAVAKKLKKTAVLTKDAPAFVVNRILTRFMGEIQNIIDEGTSFETVEKAVEPLGLPMSPIALLELVGPAIALHVSETLHGAFPERFTVSENLARVVEARKRGFYIWEDGKQVLDPEVLAILTFGDKALSEEQVRARALDAVAQEIGLMLDEGVVGEAQDIDLCMITGAGWPFHLGGITPYLDREGVSERVNGKRFLPPGVASIPA
>NZ_CP025394.1|WP_104818659.1|6320867_6321356_-|GNAT-family-N-acetyltransferase
MMIREATEDDWAAIWPFFQRIVAAGDTFTYPVDLGEEEGRGWWLLAAPNRTVVAVDEAGVVVGTAKMNTNQAGNGSHVASASYMVDPAYAGRGVGRALCEYSLAWAKAAGYRAMQFNAVVETNAYAVKLYRSLGFEVVGTVPGAFAHPEHGYVGLHVMHRAL
>NZ_CP025394.1|WP_104818658.1|6319918_6320860_+|ABC-transporter-substrate-binding-protein
MNRPPLARLAAASALLALLTACGSTTTPTAVRATAADATALPTQDVVSHLKADPALAAQLPEAVRSRGTLLLGTTQAVGSSSLPHGGQDPSGKEVGLDIDLREAVAKLLGVRWDVQYGTFPTVIPGVQNGKYDVGQDNFGVTKAREQVVDFATYLEDGQSFLGAKDLDLASVATLADLCGHTVATSPGTTFQQILTQGAALCAAAGKKPYTVQYFAETAPIFLGLANGKVDIYFGPTLSLKYDAAHLPGTKYLGQLSSTPVGFVTAKGSPVGKALAAAVNKLIADGDYDRIFAKWGVAGTGVKQSLLNPPAAL
>NZ_CP025394.1|WP_104818657.1|6319018_6319897_+|amino-acid-ABC-transporter-permease
MTAPTREPATRAAEPTAERSTLVLPLRRPGRWASAVLLLVPAVMLVHTLFTNQRFRWAVVGSYLFDGSILRGLELTLWLTAAVMVVGYLLGIVIAALRLSGNPVVGGLCFGFVWLVRSVPLLVQLLFWYELASLFPKLSLGIPFGPEFAVFRTAHLFGGLTAAFVALTLDVAAFSSEIVRGGLLSVDRGQTEAAQALGLGRRWILRRIVLPQAMPAIVPASGNLLIGMLKATSIVSVIAVQDLLNSAQLIYNQNFEIVPLLLVATLWYVLLTTLLSVGQHFLERHFARSQTR
>NZ_CP025394.1|WP_104818656.1|6318173_6319022_+|GNAT-family-N-acetyltransferase
MSATIRSATRTTSPPHLLDNPVWAALAGPHAHLAERHGRAARYPAEVSPFAALADPADPQAWADLAELVGPGGLAALTGLLDPPPGWRLEDTIPGVQLVATALRTEPLPGATALRTEPLPGATGFGPEPALEAVRLGPADVPEMLDLIKRTQPGPFLPRTVELGGYLGLRVAGRLVAMAGQRLHPPGWTEISAVCTDPAHRGRGLATRLVRAVAHGIRERGDTPFLHTSAANTTAIRLYESIGFTLRRRPDFLLLRAPGTAPDRPGTAPDRPGTAAEQERAR
>NZ_CP025394.1|WP_104818655.1|6317124_6318147_+|transporter-substrate-binding-domain-containing-protein
MPAIRSRLRRALSAGTAAATLTLGLAACGSSATPAASGTSGAGTGAIAIAAKSNGAGTPAELKVDPVAEIRAELPAEVAKRGKLVIGVGALPAGSPPLNFIGDDQRTLTGAEPDFGRLIAAVLGLEPVVQNSTWENLFVGIDSGKTDVGFSNITDTEERKKKYDFASYRQDNLAFEVAGTSGWTFTGDYRVLAGKTVAVGSGTNQEKILLEWQAKLKAAGQQLTVKYFPDNNAVHLALVGGKIDAYFGPNPAVAYQVAKDAGSPTPTRNAGTYSGAGESLQGLIAATTKKDSGLAKPVADAVNHLIKNGQYAQWLTAWHLANEAVPTSLVNPPGLPSTNS
>NZ_CP025394.1|WP_104818654.1|6316186_6316954_+|amino-acid-ABC-transporter-ATP-binding-protein
MSAPAAVELHDVHKSYGSRAVLAGIDLTVRAGEVVAVIGPSGSGKSTLLRVVNHLERPERGHVSLHGELIGVRRHRGRLRELADRQILVQRRKIGFVFQGFNLFPHLTVLDNVAAAPVATGLLAKPEAREAARALLARVGLADRAEAYPRQLSGGQQQRVAIARALALRPEVILFDEPTSALDPELVGEVLSVIRDLAASGTTLVIVTHEIGFAREVADRVVFLDGGRVLEQGPPAQVLDHPQHPRTREFLAKVL
>NZ_CP025394.1|WP_104818653.1|6315281_6316190_+|amino-acid-ABC-transporter-permease
MSESLTPVIPETPAAPEARPRPDGAERVLPLRHPGRWLVGALVLVLLAQVAHGLATNPFYQWDRFRYWFLRPVITDGLAVTLEVTAWSAVLGLAGGVLLALARLSRNPVLRVVSWGYVWLFRSVPLIVVLLFLYNFSALYRTVSLGVPFGPALWSFDESRLATDLVVAVVGLSLNEAAYAAEVVRAGLLSVDQGQHEAAAALGLPGRYRFTRIVLPQALRAIVPAYVNQLIGLVKSTSLVFYVSLLDLFGSAQSLGSTYPGDIVPLLLVATAWYVLLTSLVSAAQYYVERRYSRGVRKETAR
>NZ_CP025394.1|WP_104818652.1|6313415_6314633_-|LLM-class-flavin-dependent-oxidoreductase
MSVHPPTPPLHLAVALDGAGWHPAAWREPEARPGELFTAAYWAELVAEAEAGLLDLVTFEDSLSLQSTLPFDPDDRTDQVRGRLDAVLTAARIAPLTRHIGLLPTAITTHTEPFHLSKAIATLDYVSSGRAGLRVKVSGRADEAAHVGRRPITRVEPEALDSPAGRELLHELFTEAEEYVEVLRRLWDSWEDGAEIRDVATGRFVDTAKLHHIDFTGSRFAVRGPSITPRPPQGQPPVAALAHRAEPYRLIGRSADLGFVTPQDAAEAEAVVAEIRAAQAAAGRAAETVHVFADLVVLLDEKAGAAAARLDRLDALAGAPYRSDAYVYTGTPAELADLLEDWQRAGLTGFRLRPATLPYDLGQITRLLVPELQRRGLFRTGYEASTLRGLLGLPRPANRYASAAL
>NZ_CP025394.1|WP_104818662.1|6326589_6327297_-|response-regulator-transcription-factor
MSVLLEHPANVAAYRPTKPTAMVVIADPRVRNTVTRHLWALGVRDVIEVSSIAEARPRVTTPRDICIADVHLPDGSGLTILAETRAAGWPNGLALSAADDIGAVRSALAGGVKGYVVTGTRTNVAMPGRPGLPIGAGGLAGRMRRPGLPGAVGAPGAPGAPGAPGAQPQAYRELSGREVEVLRLVAEGQSNKAIGVAMGLSALTVKSHLARIARKLGTGDRAGMVAVALRTGIIH
>NZ_CP025394.1|WP_104818663.1|6327694_6328345_-|DUF3000-domain-containing-protein
MAAVGGHPAQGGGTGKESAPIGFRTAVEALAAARLRPELQLSVAPAPRRLAPYAHALTATVEVDGEELADGRFVLLHDPAGQEPWHGDFRVVTLTRAELEPEMAGDPMLAEVGWAWLTDALQAHGAGHAEPGGTVTHAASHYFGALAEREPSTEIEIRASWTPADGRFERHLAAWGDLLCICAGLPPTVPAPVPLPDTASLGGVVPMPARRRPRSH
>NZ_CP025394.1|WP_104818664.1|6328571_6329657_+|uroporphyrinogen-decarboxylase
MSETSAAQPGQPDARRGAAYDSAFLRAARREPVPHTPVWFMRQAGRSLPEYLKVREGVPMLESCMRPELVKEITLQPVRRHKVDAAIFFSDIVVPLKAVGIDVDIKPGVGPVIADPIRSLADLERLRPLEPDDMPYITEAVGMLVEELGATPLIGFAGAPFTLASYLVEGGPSKSHEKTKAMMYGEPELWAALVDRLAEITAAFLKIQIEAGASAVQLFDSWVGALAPDDYRRSVMPASVKVFDAVAGYGVPRIHFGVGTGELLGLMGQAGADVVGVDWRVPLNVAAERVGPGKALQGNLDPAVLYAPTHVVETKAREVLHAAQSLGGSGHIFNLGHGVMPSMDPDALTRLVDFVHRSTES
>NZ_CP025394.1|WP_158702368.1|6329666_6330686_-|DUF4349-domain-containing-protein
MRRQRVGVRRRTGTAVAGAALAAAALLAGCSSASDHSSAGLAARAPAAQAPADAAGHQPAAGQPTGGARPNTGPTVSAAARQLAYTAQLELRVADLAKAVRTAEQLTQPDGYVAEEQVQEATPGSAGTARLTLKLPTAGYHQALEQLAGLGQVIGEHRQAEDLTQQLVDLDSRLKSQQASIERVRALMNSASSIADVVSLESELGHREADLESLQHQRQELAGQVALSTVTVSLSTAAALVPPAPHPARTGFWHAVGSALDGGWQVLLTVLRGIVLVLAALAPFVLVLSPLGWAAWLVRRRRTARRAELALLETEEHRAAAEEDGEEREPAEEAGRPAP
>NZ_CP025394.1|WP_104818666.1|6330786_6331563_-|NAD(P)H-binding-protein
MENVILVTGATGVLGREVVARAVRAGVPVRALSRRSGLPSTPGVSWCTGDLVSGAGLAAAFAGVRTVIHCATDARRYRNDLPAFEQLITAARAAGVAHVVNVSIVGVDLVPFPYYRVKLEGERLLAASGLGWTNLRATQFPTLLDSALGVLAKSPVVPMVSGTGCQPVDPGEVADRLLELALGEPAGQVEESAGPRVYEAVALTRSWLKAKGRRRLVLPVRLPGRLGAALRAGGLTNPGRAVGRRSWEEYLAANVAKP
>NZ_CP025394.1|WP_104821157.1|6331641_6332517_-|RNA-polymerase-sigma-70-factor
MDIAAEFEAQRPRLFSIAYRMLGSAAEAEDAVQDAYLRWHGALHEEIGAPGAWLAKVLTNLCLNRLTSARVRREQYVGPWLPEPVRTDGGALGPLETAEQREAVSLAVLVLMERLTPAERACVVLRDAFEYGHREIAEVLDVSEASARQTYRRAKQHLAEQRPRFDSAPAPQQHLLHGFLAAAAEGSLAKLEALLAAEVTAWADGGGKVRSATRPVHGRDKVGRFLIGLLTRFTEGVDLEFAEVNGAAAVLGREQGTLIVVATVEGADGLITGVRILRNPEKLAFLESQLA
>NZ_CP025394.1|WP_104818667.1|6332560_6333145_+|Uma2-family-endonuclease
MSSLPDWMYPPREEGWYAEDLDRLTEAPRHTELIDGALVFMMSPQRSWHSRVVSALTFALEAQAPEELEVEREMTIRLDRRNRPEPDLVVAKAEYRPNRTWFDPSEVLLVVEVVSPESEHRDRTMKPRKYAEAGIPSYWRIEHEVEQVVAYVHELDDAVGAYGSPQVYQRRLERKVPFPLTLELDQLERRRRGN
>NZ_CP025394.1|WP_104818668.1|6333178_6334579_+|protoporphyrinogen-oxidase
MAEVRHVVVIGGGVAGLTAAWAARGQRVTLLEASGRVGGKLRGGEVGGVRVDLGAESMLARRPEAVELAREVGLGGELEPPSTAKAAIWSRDALRPLPGGQLMGVPGDLAALAASRVLSPEGLARAEDERATEAFEDDVAIGAYVADRLGREVVDRLVEPLLGGVYAGHADEISLRASVPALLPIARAGKPLVEGVRELTSRPSAAGPVFQGLRGGLGTLPEALAAACRAAGVDLRTDSPVQELSRTPEGWRVVVNGEVLHADAVVLAVPAPAAARLLRAEVPAAASELDGIEYAGMALVTMAFRRAELPGLTGSGFLVPPVDGRAIKASTFSSNKWGWLAESAPDSFLLRTSLGRHREEAALDLDDEELVARSLADLAEAVGLRARPYDAAVTRWRGGLPQYPVGHLDRVGRIRAAVAAAGGLAVCGAAYDGVGIPACIASARRAVNEVLTPGTGARGTEGTMGA
>NZ_CP025394.1|WP_104818669.1|6334575_6335313_+|chlorite-dismutase-family-protein
MTENVAAQAAEQQAEQPAKKKARDLNQVIRYTMWSVFRLKGELPEDRTALAAEVDALFEQLAEKDVTVRGTYDVSGLRADADLMVWWHAENSDDLQEAYNRFRRTGLGRALEPVWSNMALHRPAEFNKSHIPAFLADEHPREYVCVYPFVRSYEWYLLPDEERRAMLAEHGRMARGYPDVRANTVASFALGDYEWLLAFEADELHRIVDLMRDLRPSRARLHVREEVPFYTGRRKPVAELLNGLV
>NZ_CP025394.1|WP_158702369.1|6335339_6336335_-|glycosyltransferase
MSASPLISVILAAHDPNGSLDDCLQSILNQSFTEVEVILVRDQAAECPADQVDAWARREDRVSVVRLDGLASIGRIRNAGAERATGDYLLFLDADHLLLSSTLQAMADRLDEAYRPDVLLFGHTRLHQGKSWPGAAADLLARQRSQPFAPVQQPELFGAPAYSWDRLFRRAYWTAQRLAFPDGLHEEVATVHRAMLGAEQIAVLKWDCVQLRRRLTQHPAGSPEGSQFDVFDRYEESFGLLAEHVQLDGVKPYLFTRMVRQYLFLLNLSGAVPRGDRSRFFQRASEHYGRYLPEGYERPEGREGVKFQLVGGGKYAAFEAAKLPALFSRGR

Crispr_ID: NZ_CP025394_15

• CRISPR_ID: NZ_CP025394_15
• CRISPR_location: 7049543-7049628
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_15

Consensus_repeat	Method
GTCGGGTGGTCGGTGAGGAGGGCG	CRISPRCasFinder

spacers of NZ_CP025394_15

>15.1|7049567|38|NZ_CP025394|CRISPRCasFinder
TGGCAGGCCGGGGCGGGCTTCACCGGGGCTCCGCCGGG

CRISPR arrays and Neighbor proteins around NZ_CP025394_15

CRISPR arrays

The CRISPR arrays of NZ_CP025394_15

>merge|NZ_CP025394|15|7049543-7049628|CRISPRCasFinder
GTCGGGTGGTCGGTGAGGAGGGCGTGGCAGGCCGGGGCGGGCTTCACCGGGGCTCCGCCGGGGTCGGGTGGTCGGTGAAGAGGGCG

>NZ_CP025394|15|14|7049543-7049628|CRISPRCasFinder
GTCGGGTGGTCGGTGAGGAGGGCG	TGGCAGGCCGGGGCGGGCTTCACCGGGGCTCCGCCGGG
GTCGGGTGGTCGGTGAAGAGGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104819126.1|7061341_7062139_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NZ_CP025394.1|WP_104819127.1|7062193_7062841_-|fasciclin-domain-containing-protein	unknown	unknown	gnl|CDD|367095
NZ_CP025394.1|WP_104819121.1|7051692_7054239_-|class-III-lanthionine-synthetase-LanKC	unknown	unknown	gnl|CDD|271199
NZ_CP025394.1|WP_104821220.1|7062927_7064463_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239028
NZ_CP025394.1|WP_104821219.1|7037903_7040441_-|discoidin-domain-containing-protein	unknown	unknown	gnl|CDD|366285
NZ_CP025394.1|WP_168219639.1|7035606_7036941_+|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|223727
NZ_CP025394.1|WP_104819115.1|7043309_7044236_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_CP025394.1|WP_104819128.1|7064613_7066119_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187556
NZ_CP025394.1|WP_104819111.1|7034914_7035526_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP025394.1|WP_104819118.1|7047562_7049524_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP025394.1|WP_104819120.1|7051474_7051594_-|SapB/AmfS-family-lanthipeptide	unknown	unknown	gnl|CDD|380211
NZ_CP025394.1|WP_104819125.1|7058819_7061186_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|379262
NZ_CP025394.1|WP_104819122.1|7054752_7055415_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP025394.1|WP_158702429.1|7055700_7056426_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_CP025394.1|WP_104819116.1|7044232_7045075_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_CP025394.1|WP_104819112.1|7036950_7037808_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_CP025394.1|WP_104819124.1|7056457_7057687_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl|CDD|99740
NZ_CP025394.1|WP_104819113.1|7040631_7041849_-|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NZ_CP025394.1|WP_104819117.1|7045104_7046454_+|beta-glucosidase	unknown	unknown	gnl|CDD|274539
NZ_CP025394.1|WP_104819114.1|7041991_7043308_+|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270303

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104819126.1|7061341_7062139_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	4.03856e-06
NZ_CP025394.1|WP_104819127.1|7062193_7062841_-|fasciclin-domain-containing-protein	gnl|CDD|367095	pfam02469, Fasciclin, Fasciclin domain. This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.	7.8248e-39
NZ_CP025394.1|WP_104819121.1|7051692_7054239_-|class-III-lanthionine-synthetase-LanKC	gnl|CDD|271199	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.	2.81395e-86
NZ_CP025394.1|WP_104821220.1|7062927_7064463_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|239028	cd02110, SO_family_Moco_dimer, Subgroup of sulfite oxidase (SO) family molybdopterin binding domains that contains conserved dimerization domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). .	1.11041e-75
NZ_CP025394.1|WP_104821219.1|7037903_7040441_-|discoidin-domain-containing-protein	gnl|CDD|366285	pfam00754, F5_F8_type_C, F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.	2.8075e-26
NZ_CP025394.1|WP_168219639.1|7035606_7036941_+|FAD-dependent-monooxygenase	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	2.75249e-12
NZ_CP025394.1|WP_104819115.1|7043309_7044236_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.94117e-59
NZ_CP025394.1|WP_104819128.1|7064613_7066119_-|SDR-family-oxidoreductase	gnl|CDD|187556	cd05245, SDR_a2, atypical (a) SDRs, subgroup 2. This subgroup contains atypical SDRs, one member is identified as Escherichia coli protein ybjT, function unknown. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif consensus that generally matches the extended SDRs, TGXXGXXG, but lacks the characteristic active site residues of the SDRs. This subgroup has basic residues (HXXXR) in place of the active site motif YXXXK, these may have a catalytic role. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.92764e-143
NZ_CP025394.1|WP_104819111.1|7034914_7035526_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.17253e-13
NZ_CP025394.1|WP_104819118.1|7047562_7049524_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.96414e-68
NZ_CP025394.1|WP_104819120.1|7051474_7051594_-|SapB/AmfS-family-lanthipeptide	gnl|CDD|380211	NF033212, SapB_AmfS_lanti, SapB/AmfS family lantipeptide. Members of this family are class III lantipeptide precursors. These typically are short peptides, encoded next to the gene for the lantipeptide synthetase that creates the characteristic lanthionine (or beta-methyl lanthionine) bridges for which these natural products are named. Members of this family include SapB and AmfS, which are considered morphogens rather than antibiotics. Members also include labionin-containing peptides such labyrinthopeptins A1 and A2.	3.8783e-06
NZ_CP025394.1|WP_104819125.1|7058819_7061186_-|tetratricopeptide-repeat-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.91809e-08
NZ_CP025394.1|WP_104819122.1|7054752_7055415_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.75263e-35
NZ_CP025394.1|WP_158702429.1|7055700_7056426_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	6.1967e-41
NZ_CP025394.1|WP_104819116.1|7044232_7045075_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.03912e-79
NZ_CP025394.1|WP_104819112.1|7036950_7037808_-|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.5834e-26
NZ_CP025394.1|WP_104819124.1|7056457_7057687_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	9.54954e-122
NZ_CP025394.1|WP_104819113.1|7040631_7041849_-|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.79252e-60
NZ_CP025394.1|WP_104819117.1|7045104_7046454_+|beta-glucosidase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	0
NZ_CP025394.1|WP_104819114.1|7041991_7043308_+|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.1387e-69

Protein sequences

>NZ_CP025394.1|WP_104819118.1|7047562_7049524_-|ABC-transporter-ATP-binding-protein
MKPHRPSTTAAGTTAPGPPALDGPPALDSPSEDTARKAPVLGPPPAQRPRHPGRRLLLDLLRPHRAPLTRLAAWTVIELLPAAFSGRLLAGALDQGFLAGRPLAGCLRLLAFGLLSIVAAYGSRQVYPQLADVVEPARHALTRRVVTAELHRPADRARRPDPAAVARLTRQVEAVRDSLAGQLLIIRQFAVTLVFVLLGAASLSPRLLPLIGGPLALALLAFLLLLPRLTARQREVLTAEEEFTRLATTTFGGLRDVLACGATTRAEAELAEALDALTEARRRAAAFGALRRLTVAVGAHLPAALILLTAPALVRQHSLTPGEVVGALGYLTVSLEPALHVLVQGLGASGLRLAVTAERLATTTESALPAPAPPRTHGPVALRAVTFRYAPGADPVLDGLSLTLGPSEHLAVVGPSGVGKSTLADLLAGLAAPESGVVRPGRTATPAADRVLIPQEAYVFAGTLRANLALLAPTAPDRRLHEVGRLFGLEKLLAEGLSSHLDPMRLSPAERQLLTLARSYLSPAPLAILDEATSLLDPAAEARAEEAFRARPGPLVVIAHRIASARRADRVLLLDRTGPALGSHEQLLRDCPGYARLVDAGTAGASLTDHVGSAGVVGVRASAVPRRESMRSIGDRREAVEVRAPAADARRDP
>NZ_CP025394.1|WP_104819117.1|7045104_7046454_+|beta-glucosidase
MDFLSDLPAGFRWGAATAAYQIEGAATEDGRAPSIWDTFSHTPGKVAAGDTGDVACDHYHRWPEDLALMGRLGLDSYRFSIAWPRVVPQADGRVNPAGLDFYDRLVDGLLAAGITPFPTLYHWDLPQAQQDRGGWPERSTAERFGEYAAVVGERLGDRVTHWATLNEPLCSAWIGHLDGAMAPGLTDLTAAVRASCHLHLAHGLAVQALRATVPGAQLGIVNNLSTIEPAGDSEADLAAARRADGHVNRWWLDPVLGRGYPADMVELYGVEIPLKDADLATIAAPLDWLGLNYYFRQIVTDDPTGPAPYARQVTGPGPEFTAMPWEVHAPGLEQLLLRLTHEYGARRIYVTENGSAYEDTPAADGSVQDPERTAYLELHLAACARAVAQGAPLAGYFAWSLLDNFEWAYGYAKRFGLVHVDYPTQRRTVKASGHRYAELIRAHRSGRSA
>NZ_CP025394.1|WP_104819116.1|7044232_7045075_+|carbohydrate-ABC-transporter-permease
MTKPPASFRWTRRIVLTLLTAFALTPVLVMLSSSLKPLRDVQGPFRWIPSTLTVRPYLDIWRTVPLGRYLVNSALVSAGSTVVSVLVAVLAAYAVSRYRFRGRRAFTVTVLATQMFPGILFLLPLFLLLVDIGNSTGLPLYGSRGGLVLTYLTFSLPFSIWLLVGYFDGIPRDLDEAAAVDGCGPVRTLLRVVVPAAIPGIVAVAVYAFMTAWGEVLFASVLTNDTTRTLAVGLQGYATQTDVYWNQVMAASLVVSVPVVAGFLLLQRYLVAGLTTGAVK
>NZ_CP025394.1|WP_104819115.1|7043309_7044236_+|sugar-ABC-transporter-permease
MRLPSARARRRATPYLLLLPALLLELLIHLLPMVTGVLMSLRRLTQFFIRDWTAAPWAGLANFRTAVDFNAPVGKALLHSFWVTCGFTLLSVGLSWLIGTAAAVLTQDAFRGRGLLRALFLVPYALPVYAAVITWSFMFQRDTGLVNHLLHDQLHLTSGRPFWLIGDNSFTALLTVSVWRSWPFAFLTLTAGLQNIPRELYEAAALDGAGIWQQIRRITLPSLRPVNQVLVLVLFLWTFNDFTTPFVLFGRAAPVAADLISVHIYQASFVTWNFGAGSAMSVLLLLFLLLVTAVYLFATTLPERRSRR
>NZ_CP025394.1|WP_104819114.1|7041991_7043308_+|sugar-ABC-transporter-substrate-binding-protein
MRASRTVHPLAATALTAALALAATGCGGGTSGSASGSPTTLTYWASNQGTSLENDKQVLEPELKKFEQQTGIKVSLEVIPWSDLLNRILAATASGQGPDVLNIGNTWSASLQATGALLPFDADAFGRIGGKDRFLPATLASAGAAGQDPAAVPLYSMAYGLYYNKKLFQAAGLDHPPATWEELVADGKKLTTGGHYGIAVEGGNVSENVHHAFTLGQQHGAEFFDASGRPQFDSPAAVTAVKTYVDLIAGDRIAAPGNAEYANNQSVTDFASGKAAMLMWQAAGANLKSHGMAAEDYGVAPVPAPAGATGAAQTSSMVAGINLAVFKNTHNKDGALKFVQFMTSAAEQTQLNKSYGSIPPVSDAQGDPAFATPELKTLSEVLAHRARPLPQVAAESQFETLVGTAVKNLFAAAAAGQPVTEATVKAELAKAQQQMPAS
>NZ_CP025394.1|WP_104819113.1|7040631_7041849_-|ROK-family-transcriptional-regulator
MTAPGKQTVRDLRRGSRAILLRRVYFDGPISRQELGPATGLSAGSISNVTAELLADGLLEECGSVESEGGRPRILLRVPPGAAHLIGVDVGETQVRVALFDLALTELAASDHPLTDCGHDVAHVVELVLGGVAEVLHRTGADPASVLGVGVGVPGIVEQGAPVDDGLGITVHSQTIGWDAVPLGKLLRAGTALPLYVDNGAKTLGQAEMWYGAGRGARHAVIALFGSGVGACVIVDGARFRGATSSAGEWGHTRVHVGGRRCRCGSRGCLEAYVGAEALLERWGRAPAGASEKAGLAALLAAAEAGDPATGELLDEAAEYFGSAIADLVNLFNPERIVIGGWAGLLLGPRLLPGIRRAAADYALHFPHAQTTITLGTLGPDAVTVGAATLPLSHFLDSGGDPRPR
>NZ_CP025394.1|WP_104821219.1|7037903_7040441_-|discoidin-domain-containing-protein
MATLLGVAALSLGGLTLPQVSAQAATDALLSQGKAATASSAENATTAAAEAVDGDTGTRWSSTFSDAQWLQVDLGASAAIDKVVLNWEAAYGKSYQIQTSPDGATWTTIYSTTTGTGGTETLNVNGTGRYVRMNGTARGTAYGYSLWEFQVYGTPAAATCGTANAAQGKAATASSAENANTPASAAVDGDTATRWSSAFGDPQWLQVDLGSSRQLCQVVLNWEAAYGKSYQIQTSSDGATWTTIYSTTTGTGGTETLNVNGTGRYVRMNGTARGTAYGYSLWEFAVHTTDGGVPPVQGGGDLGPNVLVFDPSMTDIQSKVDAVFAKQETNQFGTDRYALLFKPGTYNGGLNAQIGFYTSVAGLGLNPDDTLINGDLTVDAGWFNGNATQNFWRSAENLALNPVSGTDRWAVAQAAPLRRMHIKGGLNLAPNGYGWASGGYIADSKVDGQVGNYSQQQWYTRDSAIGGFSNGVWNQTFSGVQGAPAQSFPNPPYTTLPSTPVSREKPYLYLDPAGNYRVFVPAKRTDAVGTSWANGATPGSSLPLSQFYVVKPGATAATINAALAQGLNLLFTPGVYHVDQTIDVTRPDTVVLGLGLATIVPDNGVTALRTEDVDGVRLAGLLIDAGPVKSPVLLQLGPAGSTADHAADPTSMQDVFVRVGGAGAGVAGTAVEVNANSTIVDHTWIWRADHGTGVGWTVNPADYGMVVHGNDVLATGLFVEHFEKYDVEWSGERGRTIFFQNEIAYDAPNQAAEQNGATKGWAAYKVDDTVRTHEGWGLGSYCYFNVDPTIHVDHGFEAPNTAGVKFHDLLVVSLGGNGQYDHVINSTGGATSGTSTTPSTVVSYP
>NZ_CP025394.1|WP_104819112.1|7036950_7037808_-|alpha/beta-hydrolase
MTDSWDTAVTPFELRLGDHAFQAYSAGPRTGELVLLLHGFPEFADSWGPALPALGAAGYHAVAVDQRGYSPGARPEPVAAYAVPELVADVLGFAEALGAERFHLLAHDWGGLVAWALAARHPERLRTLAVLSTPHPAALHEALGLANDQAERSRYVQLFRAPDHAAERVLLAEEAAALRGAYRGHLPEEQVTRNVERLVAGALTGGLNWYRAVEGTLRVEAGPVTVPTLYVWGTEDQALGRDAAELTAKYVEGPYRFLALDGASHWLPECDHDRYLPAVLAHLAT
>NZ_CP025394.1|WP_168219639.1|7035606_7036941_+|FAD-dependent-monooxygenase
MVDQGTVSGRGTAVVIGGGHAGLLAAWALRGYADEVVVVERDRYPAETDFRAGVPQGRHAHLLLEAGHRALEEQMPGIRAELVAAGAVWIHMAEELRWLSPAGWMAKHESDLRLLSGTRPVLERAVLERVRTEPSIRIEEGTEVVGLLGSPGTVTGVRVRERGEGGEVREIPAELVVDASGRSTSVPGWLAELGVPPVPEERVDPGVKYASRLYQRPAGAEFDFEALYVQAKAPDVPQVGVLLPVENDRWIVSLGGMRGGHPEAGEAGFLRHLDLLRDSPMREAVLAATPVTEVRGFLPGPGVFRHYERSAPDGLVVLGDASCTFNPVYGQGLTVAAFGAGALRAAVAQYGGISHPAARAARKAVALVSKEPWVMSSGEDVRFAATTGGPSGVLVKVQHRFLDRVLQRATKDPHIAAVFYEVMSLVTPSQVLFRPANLASVLRG
>NZ_CP025394.1|WP_104819111.1|7034914_7035526_+|TetR/AcrR-family-transcriptional-regulator
MQSAAPAMGRRERNKQKVQERLYDSALGLITERGYDGTSIEDIAERADVARGTFFNYFQRKEDLIVEWGQRRRARLAAGMLEEGAPGQGAVAQLEHCMTVLGVLSESERAVTIAMLTAWVKAGRPVLEEPYVAETFARIVALGVAGGEFQPGVSAEQVGHVLRDLYLGTLYRWCRQGEPGEPGALVAELHAVLRMVIEGIGAR
>NZ_CP025394.1|WP_104819120.1|7051474_7051594_-|SapB/AmfS-family-lanthipeptide
MEILELQSLETPVEDTTANASTLSVVNCGVSTVSTILCL
>NZ_CP025394.1|WP_104819121.1|7051692_7054239_-|class-III-lanthionine-synthetase-LanKC
MDARYEAYSFADPHYYDSPVTWGAPEEFTETGEPAPEGWERRDRGTWAGLHPVGVRFPDQGWKIHVSAGLANAEQVLATVHAYCLRERLPFKFLRGLPVLQLQNAKYAPRSGSGKFCTLYPLDEAQLTRCLEELGTALDGEPGPYVLSDLRWRQGPLYLRYGAFVERWLRSPSGVPELAFADPDGTLVPDVRAPVFELPAWAPVPEVLRETLESRRTAKGTGLPYRVERALHFSNAGGIYLARDPETDTRLVLKEARPYAGLDQRGTDAVARLHHEAEMLRRLDGVPEVPRLIAELTSWEHEFIAQEYVEGETLNAWLAGRYPLVHPDCTEAEVAAYAAEALELLAKVEAGLARIHERGLVFGDLHPHNLLVRPDGRIAFIDFELASPADTFVAPALGAAGFAVPGLTGREVDLRALAALRLWLFLPLQQLLAHDPGKARQLTEAAAARFPLPPDYAETTRRGLVQPAATAAPLPEEEHRLLLGRLDGVEPDWPGLRAALATSIRASATPDRTDRLFPGDIAQFEVDALSLAYGAAGVLYALHVTGAGTDPAHARWLIEAERRRAPRPGLYTGGHGVAYTLDLLGQREEARELLDRLLDLPLEAQGGDLAGGLPGTLLTLLHFARQAPELLDRAEAAAEALTRWQDKLAAPEQAPLGLLLGGAGQALALLRTFEATGRTELLDRAEQTLAAELDRCVTVPDGTLQVPDGTRVLPYLAEGGTGIGLVLGELLRHRPHSPLAGHSVALQRSAETEFVVQPSLFNGRAGLLLHLDRLRPRPAAVIDRHRRALALHAVPHKGGLAFPGEQLIRLSSDLATGTAGVLLALGAALAGTPGLPFTDPLPPAGDAA
>NZ_CP025394.1|WP_104819122.1|7054752_7055415_-|response-regulator-transcription-factor
MSGAVRVVVADRRRTVAEVLATGLHQVGLTTHAVTALAEARALAAAGRADLVVADIGLLTAGPTAAGPSWGRDLPVPLVVLSDGSRDAELVTAAVRAGVRGWVPKDSALQHLLVVIRGVLRGETWLPPVLLTTVVDELVALRSAQDEGAERLATLTAREREVLGCLCAGLSRPEIGRRLFLSTNTVRTHVQNMMLKLDVHSSVAAVALANRVGPPPLPEP
>NZ_CP025394.1|WP_158702429.1|7055700_7056426_+|response-regulator-transcription-factor
MVETPAGPGHGAGAGRTAAGVGAGAGRSGGGLALVVADAERLLADALALALTGRGYRVRATATTRNGLLRAVLHHRPDACLLDLHLSDGRALDVIEAIHRAVPTTRILALSREADPGVVEIAIEAGAAGYLSKDRGVEALDRALRRITAGELFVEANLTLEARQGRPAPGGRSLRWLTHRELEVLRRLTEGDGTVEIARALDMTTNTARTHVQNVLDKLGVHSRLEAVALANRLKTEQRSS
>NZ_CP025394.1|WP_104819124.1|7056457_7057687_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MSMSTSVPRSVTTVRLPVADDLSVPYTRTEICAEAREAARVVLESGWVTSGPQTQLFEGEFAGLVGARHAVAVSSGTAALELVLRDLRLPPGGLVLVPDLTFCGAAQAVLHAGLRPLLVDVEPATGMPTAATVRRAVRAFGRPEALMALHYAGAPAPLRELGEAAGLPPHRVVEDAAHALGTFLGGRPVGALSRAACFSFAAGATLPIGEGGMITTEDDDLAAGCRRARLHGMSTDDWRRHQPGGAWQYAVEEPGLKANLTDLQAAIGRAQLRHLAGWQRRRAVLAARYTARLSGVPGLTTPRPPTAGLHSWQLYVLRVGPEYPLRRNRLVARLAEHGIGSSVHFIPLHRLGYLRRAALRPPEGLPGADALFPELLSLPLHPGLTESQVDRVCAVIAEAEADPGPGVRP
>NZ_CP025394.1|WP_104819125.1|7058819_7061186_-|tetratricopeptide-repeat-protein
MQTDPPAAEPPALGPLLRGLRTRAGLSQEELSHRSGISVRAVADLERGRARGPQRRTVQALAQGLGLDEAGARQLEQAASPGRSRPHTARPAATTESGAPGRPVRTAEPRTALLLPRAVADFVGRDRELAEVSAVLDRADAAHAPVVLVCGQPGLGKTAFAVHAAYRLAERFPDGQYSIDLLGMAEEPTSPHEALGRVLSALGVPAGGIPAGTEARSGLFRTVVRDLRAVFVLDNAADEEQIRPLLPGAGRCLTIVTGRRTLAGLEAVHRIELALLQPGEAVELLGRILGPQRVGEEQQAAHRLAELCGQLPLAVRIAGQRLAGRADERLGKMAVQLAREDRRLDLLQAGTLRVRNAFELSYRQLSPPAQVVLRRAALTAGVDFSLESAARLARLPLREAALHADELVDAGLLQPHASAERYRFHDLLKVFAGERLAAQEQPSEREAALDSFAQWLLARTRAAASHFDAKRRHDGSAPDPDPATAPTDRESAKEWLEAEQAEWQAALHRLLAIGRYQEVIATADAVHWFAELNQHWDVWAEVFRCAAKAAEALGRHDDQSTQLTNLAWSLNVSGDDPGLALAAADAASAVARSIEDPQAVCSALAHGATALHRLGRVSEAMERLRQAAELLAPLPESGARLAELFTLNTLGRYLREAGRAEEALEVHRRSDAICRAGVPGKPPELMALYRAATSLHLGNDLVALARWPEAEPWLREALAGFEPADMPTWTAPSRLALGRVLARTGRPEEARRLLRAAHTSLAALRSPQEAEAAAELAALDRPDAEPAS
>NZ_CP025394.1|WP_104819126.1|7061341_7062139_-|nucleotidyltransferase-domain-containing-protein
MSVEISAPPVTGLDPDGFLAREGSIDLVPDLFAPVVAAAWEGIAAAFGPELLHSAYLYGSIPRGTARPGSSDLDLLLALHRPPTPADRAAAKDQEAFLDDSFPQIDGVGILLYDTATLLSELERYDLGWFLACLCTPLLGPDLAEQLPRYRPTPLLARETNGDLHLAVPRWQAQRDTADPQRLTRIVSRRLLRSALTLVMPRWGGWTSDLARSAEIAAHYYPERAEQLRRAATATPADLPMLLDELAPWLAAEYLAVHGPKAPRP
>NZ_CP025394.1|WP_104819127.1|7062193_7062841_-|fasciclin-domain-containing-protein
MFTLRSKTVAALLAAGALATGLTACSSGSSSNSASSSASSPASSTSTGSTGSSAAAMTDQPFGAACAAVPKDGAGSFSGMAKDPVATAASNNPLLSTLVTAVKTAGLVDTLNSAQNVTVFAPTNDAFAKLPKDTLAAVLADKAKLTKILTYHVSPTRLAPTALAGTHKTLEGSDLSVTGSGEDFTVNTNAKVLCGNVQTANATVYIVDTVLMPTS
>NZ_CP025394.1|WP_104821220.1|7062927_7064463_-|molybdopterin-dependent-oxidoreductase
MGAAVTGLAAAAAAVGAGELAAALTGPDSAPVIAVGSAAIDLTPTPLKEYAVRTFGTHDKPVLLTGIYLTMAALAALAGLIAARHRRTGAALFLLFGALGTWAALSRPTATASHALPSLAAAAVGAATLLFLTSRLPAAAPEIDPSPVSPAEPPRPARRTFLLATTGTFAIAAVAGYGGRRLADSRSDVSAARAAIRLPAPPVPARPIPASAHPAVPGLPGFRTATDDFYRVDTALTLPRIDPREWTLRVRGLVDHPLLLSFDELLRRPLTELDHTLSCVSNEVGGPYVSTTRWLGASLPDLLRQAGVRAGADQLVGRSSEGMSIGTPLAAVLDGRTALLAVAMDGEPLPLAHGFPCRTVVPGLYGYTSATKWLVDLEVTTFAAYDPYWVRRGWDRTGLVRTASRIDVPAPFARVPAGEVTVAGTAWATHRGIAAVEVRVDGGPWAEATLAADAGPDLWRQWSYQWSNARPGTHRLEVRATDATGAVQPEARAAPFPSGATGWHSTVVTVT
>NZ_CP025394.1|WP_104819128.1|7064613_7066119_-|SDR-family-oxidoreductase
MPSTPPPAPAAPQRCLVTGATGYLGGRLVPELLEAGHRVHCLVRDPARLRDHPWRAEVTVVTGDVTRPDTLAGAFEGIDVAYYLVHSLGTGPGFEQTDREAARAFGEAAAKAGCRRIVYLGGLVPRGVPEAELSPHLRSRAETGRALRAGGVPVVELRAAVVLGSGSVSFEMLRHLTERLPMMVTPSWVDTRIQPIAVRDVLRYLAACADPGALPPDTDRVFDIGGPEVLTYREMMRRYARIAGLPRRVIVPVPVLTPRLSSHWVGLVTPVPNALARPLVESLRHEVVCGEHDIARWVPDPPEGLLGFDRAVRLALKRIQDAEVTTRWSSASLPGAPSDPLPTDPAWAGGSLYEDLRERTVTTPPETVWRTIEGIGGSNGWYSLPLAWSVRGRLDRLVGGVGLRRGRRDQQRLRVGDALDFWRVEEIEPGRLLRLRAEMRLPGLAWLELTVTPTPTGGTHYHQRALFHPHGLAGHAYWWSVAPFHSLVFNAMADNITGNHP

Crispr_ID: NZ_CP025394_16

• CRISPR_ID: NZ_CP025394_16
• CRISPR_location: 7449015-7449107
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP025394_16

Consensus_repeat	Method
CACCCGGATGTTCACGCTCACACC	CRISPRCasFinder

spacers of NZ_CP025394_16

>16.1|7449039|45|NZ_CP025394|CRISPRCasFinder
GCCATCTGCAGCCGCTGCCGCATCGGATCGTCCTCCACCATCAGA

CRISPR arrays and Neighbor proteins around NZ_CP025394_16

CRISPR arrays

The CRISPR arrays of NZ_CP025394_16

>merge|NZ_CP025394|16|7449015-7449107|CRISPRCasFinder
CACCCGGATGTTCACGCTCACACCGCCATCTGCAGCCGCTGCCGCATCGGATCGTCCTCCACCATCAGACACCCGGATGTTCACGCTCCCACC

>NZ_CP025394|16|15|7449015-7449107|CRISPRCasFinder
CACCCGGATGTTCACGCTCACACC	GCCATCTGCAGCCGCTGCCGCATCGGATCGTCCTCCACCATCAGA
CACCCGGATGTTCACGCTCCCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025394.1|WP_104819428.1|7436361_7437228_+|TIM-barrel-protein	unknown	unknown	gnl|CDD|163190
NZ_CP025394.1|WP_104819440.1|7452787_7453696_+|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|225088
NZ_CP025394.1|WP_104821272.1|7457250_7457832_-|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_CP025394.1|WP_158702456.1|7455572_7456232_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104819429.1|7437258_7438155_+|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl|CDD|130569
NZ_CP025394.1|WP_104819435.1|7445053_7445413_+|VOC-family-protein	unknown	unknown	gnl|CDD|380093
NZ_CP025394.1|WP_104819432.1|7441217_7442477_+|allantoicase	unknown	unknown	gnl|CDD|237319
NZ_CP025394.1|WP_104819447.1|7460249_7461095_+|aminopeptidase-P-family-protein	unknown	unknown	gnl|CDD|376349
NZ_CP025394.1|WP_174805590.1|7459167_7460238_+|oxidoreductase	unknown	unknown	gnl|CDD|99782
NZ_CP025394.1|WP_104819439.1|7450801_7452280_+|cation:dicarboxylase-symporter-family-transporter	unknown	unknown	gnl|CDD|234968
NZ_CP025394.1|WP_104819431.1|7439863_7441204_+|allantoinase-AllB	unknown	unknown	gnl|CDD|238640
NZ_CP025394.1|WP_104819436.1|7446400_7447297_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104819441.1|7453957_7455181_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NZ_CP025394.1|WP_104819430.1|7438559_7439702_+|glycerate-kinase	unknown	unknown	gnl|CDD|376844
NZ_CP025394.1|WP_104819437.1|7447339_7448200_+|metallophosphoesterase	unknown	unknown	gnl|CDD|277368
NZ_CP025394.1|WP_104819442.1|7455342_7455603_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104819444.1|7456402_7457068_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP025394.1|WP_104819434.1|7444224_7445004_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|224332
NZ_CP025394.1|WP_104819433.1|7442519_7443977_+|catalase	unknown	unknown	gnl|CDD|163712
NZ_CP025394.1|WP_104819445.1|7458056_7458947_+|metal-dependent-hydrolase	unknown	unknown	gnl|CDD|378401

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP025394.1|WP_104819428.1|7436361_7437228_+|TIM-barrel-protein	gnl|CDD|163190	TIGR03234, OH-pyruv-isom, hydroxypyruvate isomerase. This enzyme interconverts tartronate semi-aldehyde (TSA, aka 2-hydroxy 3-oxopropionate) and hydroxypyruvate. The E. coli enzyme has been characterized and found to be specific for TSA, contain no cofactors, and have a rather high Km for hydroxypyruvate of 12.5 mM. The gene is ofter found in association with glyoxalate carboligase (which produces TSA), but has been shown to have no effect on growth on glyoxalate when knocked out. This is consistent with the fact that the gene for tartronate semialdehyde reductase (glxR) is also associated and may have primary responsibility for the catabolism of TSA.	1.51165e-95
NZ_CP025394.1|WP_104819440.1|7452787_7453696_+|FtsX-like-permease-family-protein	gnl|CDD|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	1.06316e-37
NZ_CP025394.1|WP_104821272.1|7457250_7457832_-|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	6.18173e-43
NZ_CP025394.1|WP_104819429.1|7437258_7438155_+|2-hydroxy-3-oxopropionate-reductase	gnl|CDD|130569	TIGR01505, 2-hydroxy-3-oxopropionate_reductase, 2-hydroxy-3-oxopropionate reductase. This model represents 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60), also called tartronate semialdehyde reductase. It follows glyoxylate carboligase and precedes glycerate kinase in D-glycerate pathway of glyoxylate degradation. The eventual product, 3-phosphoglycerate, is an intermediate of glycolysis and is readily metabolized. Tartronic semialdehyde, the substrate of this enzyme, may also come from other pathways, such as D-glucarate catabolism.	7.57883e-125
NZ_CP025394.1|WP_104819435.1|7445053_7445413_+|VOC-family-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	7.13405e-20
NZ_CP025394.1|WP_104819432.1|7441217_7442477_+|allantoicase	gnl|CDD|237319	PRK13257, PRK13257, allantoicase; Provisional.	8.03926e-161
NZ_CP025394.1|WP_174805590.1|7459167_7460238_+|oxidoreductase	gnl|CDD|99782	cd06185, PDR_like, Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur [2Fe-2S] cluster domain. Although structurally homologous to FNR, PDR binds FMN rather than FAD in it's FNR-like domain. Electron transfer between pyrimidines and iron-sulfur clusters (Rieske center [2Fe-2S]) or heme groups is mediated by flavins in respiration, photosynthesis, and oxygenase systems. Type I dioxygenase systems, including the hydroxylate phthalate system, have 2 components, a monomeric reductase consisting of a flavin and a 2Fe-2S center and a multimeric oxygenase. In contrast to other Rieske dioxygenases the ferredoxin like domain is C-, not N-terminal.	8.25749e-79
NZ_CP025394.1|WP_104819439.1|7450801_7452280_+|cation:dicarboxylase-symporter-family-transporter	gnl|CDD|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	3.25023e-167
NZ_CP025394.1|WP_104819431.1|7439863_7441204_+|allantoinase-AllB	gnl|CDD|238640	cd01315, L-HYD_ALN, L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in biotechnology). But L-HYDs differ by having an L-enantio specificity and by lacking activity on possible natural substrates such as dihydropyrimidines. Allantoinase catalyzes the hydrolytic cleavage of the five-member ring of allantoin (5-ureidohydantoin) to form allantoic acid.	0
NZ_CP025394.1|WP_104819441.1|7453957_7455181_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.78616e-25
NZ_CP025394.1|WP_104819430.1|7438559_7439702_+|glycerate-kinase	gnl|CDD|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	6.04103e-157
NZ_CP025394.1|WP_104819437.1|7447339_7448200_+|metallophosphoesterase	gnl|CDD|277368	cd07425, MPP_Shelphs, Shewanella-like phosphatases, metallophosphatase domain. This family includes bacterial, eukaryotic, and archeal proteins orthologous to the Shewanella cold-active protein-tyrosine phosphatase, CAPTPase. CAPTPase is an uncharacterized protein that belongs to the Shelph (Shewanella-like phosphatase) family of PPP (phosphoprotein phosphatases). The PPP family is one of two known protein phosphatase families specific for serine and threonine. In addition to Shelps, the PPP family also includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, PrpA/PrpB, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.43229e-16
NZ_CP025394.1|WP_104819447.1|7460249_7461095_+|aminopeptidase-P-family-protein	gnl|CDD|376349	pfam00557, Peptidase_M24, Metallopeptidase family M24. This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.	4.10206e-22
NZ_CP025394.1|WP_104819434.1|7444224_7445004_+|helix-turn-helix-domain-containing-protein	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.82839e-24
NZ_CP025394.1|WP_104819433.1|7442519_7443977_+|catalase	gnl|CDD|163712	cd08156, catalase_clade_3, Clade 3 of the heme-binding enzyme catalase. Catalase is a ubiquitous enzyme found in both prokaryotes and eukaryotes, which is involved in the protection of cells from the toxic effects of peroxides. It catalyzes the conversion of hydrogen peroxide to water and molecular oxygen. Catalases also utilize hydrogen peroxide to oxidize various substrates such as alcohol or phenols. Clade 3 catalases are the most abundant subfamily and are found in all three kingdoms of life; they have a relatively small subunit size of 43 to 75 kDa, and bind a protoheme IX (heme b) group buried deep inside the structure. Clade 3 catalases also bind NADPH as a second redox-active cofactor. They form tetramers, and in eukaryotic cells, catalases are located in peroxisomes.	0
NZ_CP025394.1|WP_104819445.1|7458056_7458947_+|metal-dependent-hydrolase	gnl|CDD|378401	pfam10118, Metal_hydrol, Predicted metal-dependent hydrolase. Members of this family of proteins comprise various bacterial transition metal-dependent hydrolases.	3.98724e-95

Protein sequences

>NZ_CP025394.1|WP_104819437.1|7447339_7448200_+|metallophosphoesterase
MAPMEEVSPASGACYVISDVHGHLADLLAGLRGHGLLDEGGHWSGGEARLWFLGDLTDRGPDGLGVIDLVRRLGTEAAADGGRCEVLLGNHEVLLLGARHFGDRPFQGRTGVATSFLGLWLRNGGRPSDLAGLDQDRIDWLSGLPAMAREGGHLLVHADSTAYLEYGRTVEAVNDAVRTVLAAADIHAWRDCFSRLTRRFAFRGEEGPQQVGEVLAVFGGDRLVHGHSPIPVLLDRFGPADLDGQREPELGGALVYAAGLALAVDGGRGTEDAEGRLLIVRLPEPV
>NZ_CP025394.1|WP_104819436.1|7446400_7447297_+|hypothetical-protein
MSRRVVLGGGVAAAAWAGLGRGAAAQGVAAVDRSLVLAVDQGSRRVLVADANELPWQGERPGLWGWSADDVPGLGGDAWWAVSEAKHRRWRGQRWLVVCATGGLAALVSFPEGRVHWSARPGGNPHSVELLPDGRPVVASADGFLTLYGADATPVRHAFAGAHGLQWDARRRLLWALGDTALTAFTVGARLEAVRSVPLPTPGGHDLALVAADPDLLWVTTNRHVYRYAIPTGTFLAAPADGPGVKSVGDDPRSGQLLTVHPEPGNPSPWCTATLTFTRPDGTARLARASLYKARWLA
>NZ_CP025394.1|WP_104819435.1|7445053_7445413_+|VOC-family-protein
MWWGPALEAPDPAELARFYHQLLEWPIVHEEPGTSVLGAPGGAFLVCQQAAGYQRPVWPPVPGAQRPMMHFDFQVGDLAEATAEALALGATLAEHQPQDHVRVLLDPAGHPFCLCLDQG
>NZ_CP025394.1|WP_104819434.1|7444224_7445004_+|helix-turn-helix-domain-containing-protein
MSAQRRGSRATLAPGGRGPYAVLQRALRLLEAVDRHPAGVSLGALARELSLPLTTVQELAEVLETEGYLGYQDGEWVLGGTFSLLGRQNREDLLRSRLERQLLDLRDELGAAVYFSRYHEGELSVEAVAASEEAPAVHEWVDFRATAHASAIGKCLLSQLDHDGRRDHLARHPIARLTARTITDPEQLMHRLERQPSTVPVLDLQEYSLGTVCAAVPVTAGSTVGCLATSLPVSQVHRLRAAAELLADRAAPLMVAMAV
>NZ_CP025394.1|WP_104819433.1|7442519_7443977_+|catalase
MSKILTTESGAPIADNQNSASAGEYGPLLIQDQQLIEKLARFNRERIPERVVHARGSGAYGYFEVTDEVSQYTKADFLSAVGKRTEVFLRFSTVAGALGSSDAVRDPRGFALKFYTAQGNYDLVGNNTPVFFIKDPIKFPDFIHSQKRDPFTGVQEADNVWDFWAHSPASTHQITWLFGDRGIPASYRHMNGYGSHTYQWVNEAGEAFWVKYHFKTNQGIRSLDGSQSAEVLGADADSHQRDLHQAIERGVFPSWTLYVQLMPVAEAATYRFNPFDLTKVWPHADYPLVKVGRLVLNKNPDNVFAEVEQSAFSPNNFVPGIGASPDKMLQGRLFAYADAQRYRLGVNHTQLAVNAPRATSADNYGQDGFSAVNNGRRKNYEPNSYDGPTQTDEALAAPTRLDGYTGTYTTPAHSKDDDFFQAGELYRLMSEGEQERLINNIAGFLSRVSREDVIEKNLAHFHAADPTYGARLAAAVAKLRAGDEG
>NZ_CP025394.1|WP_104819432.1|7441217_7442477_+|allantoicase
MSTSQNPSAPFTELVDLASRLLGAGVVATNEDTFADAENLLVAKPAEFRPHTFGHKGQIMDGWESKRRRGVSAEQPHPTDEDHDWAIVRLGVPGVIRGVIVDTAHFTGNYPETGSVQGASIPGIPSVEELAAADWVDLVPRTALQGNTAHEFAVADETRYTHVRLNIWPDGGVARLRVHGEVLPDPRDLDGLTFDLAAQEYGGVAEAASDRYFSSPHNLNAPGRASVMGEGWETRRRRDKANDWVQIALAGGGEVLAAEVDTTHFVANAPGWADLVGFDASDGADPAEGEWFELLPRTRLQPDTRHRLRLAGGRPVTHVRINVYPDGGLARLRLTGRLTEAGRAALALRWFNALPAAEASTALVEAGLLQAEAAALTAARPLADAAATTTAVAALHPADGPDGEHTSRRRSAVWRLLGV
>NZ_CP025394.1|WP_104819431.1|7439863_7441204_+|allantoinase-AllB
MSPSQVVRSRRVVLPEGERPADVLIRDGKIAAVGEYGSLSADTVTELGDTALLPGLVDTHVHVNEPGRTEWEGFATATKAAAAGGVTTIIDMPLNSVPPTTTVDGLAAKRKTAEGQAWVDLGFWGGAIPGNVPDLAPLHEAGVFGFKSFLAPSGVDEFPHVEQADLELALAEQARIGALAIIHAEDPAVLEAAPQTPGVHYRDFLASRPDDAEAAAVARLLDTARRTGARVHILHVSSAAVLPLLRQAREDGVQVTAETCPHYLTLAAEEVPDGDTAFKCCPPIRDESNRDRLWAALAAGEFIAVVSDHSPSTPDLKLLQRYGGSGDFAAAWGGIASLQLGLPAIWTEARRRGHSLAEVVRWMSSGPASLVGLTGTKGAIAVGCDADLVAFDPDADFAVHAEELHHRNPVTPYAGKTLSGAVRTTWLRGRVVDVAAAPFGRQITRS
>NZ_CP025394.1|WP_104819430.1|7438559_7439702_+|glycerate-kinase
MPATPTQGHVVVAPDKFKGTLEGAEVAAHLAAGIRRVLPGVEIRELPVADGGEGTLAAALAAGFRRVPVKVAGPTGLPVDAAIAVRDEIAVVELAQASGLARLPGGRTSPLGAGSYGVGQLIARAVAQGAKTVVIGLGGSACTDGGAGMVQALGVGLYDAEGVELGPGGGALRRLDRLDLGSLADGLAGVEVVVACDVDNPLLGPRGAAAVYGPQKGADEEDLVVLEEGLTRFADVVREVTGRDVREAPGAGAAGGVGFAALALLGATMRPGIELLLELLGFDEAVRGARLVVTGEGCLDAQTLHGKAPAGVAAAATRAGVRVAAVAGRLELSESQWRAAGFTAAYALTDLAEQPGDSMTRAGELAEVAGERLATDLLKP
>NZ_CP025394.1|WP_104819429.1|7437258_7438155_+|2-hydroxy-3-oxopropionate-reductase
MSDSRKIAFIGLGIMGSPMAANLVKAGHHVTGFNLQQAAIDALVAAGGHGATSIADAVKDAEVVITMVPADPQVEQVILGEGGVLENAKPGTLVIDMSSITPQTSIKVAKAAKEKGIRTVDAPVSGGEAGAVEAVLSIMVGADDAADFAEAKPLFDALGTTVIHVGPAGAGQTVKAANQLIVAVNIQVLAEAVVFLENAGVDLPAALDVLGGGLAGSTVLNRKKANMIDRQFAPGFRIDLHHKDMGIVTDAARAVGAALPVGAVVAQLVASARANGDGSLDHSALLRGVERLSGREVK
>NZ_CP025394.1|WP_104819428.1|7436361_7437228_+|TIM-barrel-protein
MTHVSAASQHSYTVNLSILFSELPLLERPAAAAAAGFTAAELWWPFGENHTPSQAELDELRKAFTDAGVQLTGLNFLDDLSKGQRGTVSVPSQRERFRENIAVTVSLAESLGTKALNALYGNRVAGVDPAEQDELALENLTLAAQAAHSIGAILLVEALNRPESPDYPLVSAAAAVEVVDRVNAATGLGNAKFLCDLYHLSMNGEDLAAVIDTYADRFGHVQIADNPGRNEPGTGSLDFEDLFARLTAAGYGKAGGSAAGGRIGLEYRPAGGVSADSFEWLPRDLRAN
>NZ_CP025394.1|WP_104819439.1|7450801_7452280_+|cation:dicarboxylase-symporter-family-transporter
MNASVTRLTPLAIVGRPHPVPTQSPPGAPVSFPLTSDEPSGAAQDRPARPPRHDRTQRLYLAVLLAVLAGILVGLAAPDFAVQLKPVGTGFVNLIKMMISPVIFCTIVLGIGSVSKAAKVGRVGGLALGYFLLMSTVALALGLVVGNLIEPGSGLHLTQALAKSGHAQAAAGGSQGTADFLLGMIPTSFFSALTEGKVLQTLLVALLAGFALQALGPAGAPVLRGVEHLQKLVFKVMSMIMWVAPVGAFGAMAALVGATGTAALKSLAVVMLGFYLACALFVVVVLGLLLRLVAGVNVFALLRYLGREFLLILSTSSSESALPRLIAKMEHLGVSRPVVGITVPTGYSFNLDGTAIYLTMASIFVSQAMDKPMDFGQQLSLLLFMIIASKGAAGVTGAGLATLAGGLQSHRPELVDGVGLIVGIDRFMSEARALTNFAGNAVATVLIGHWTKELDHDRLHLVLAGGAPFEEAPATPAIPAQQAAGHDLAETP
>NZ_CP025394.1|WP_104819440.1|7452787_7453696_+|FtsX-like-permease-family-protein
MRAQFALSEIGVGLRRNLTMTVAVVISVAVALALAGASLLVRAQVDSMKGYWYDRAEVDIYFCTRADALYTPQCVAGAATDRQIAEVKAELDKMAVVRSSTFLSATEGYRRWKAMNPDNQLAAVVGPEAIQQAWQVRLTDPAKYDLIRSAFTGQPGVHSVADQRSVMENVFLLLNALQTAALLLTGLMLSIALLLIVNTVRVSAHSRRRETGIMRLVGASNFYVQIPFVAEAVFAALLGAALASGLLLAGHYVISHLIGSRIAFIHLIGISAVWSVIPLLVLAGTGMAAGAALVTLRKHLKV
>NZ_CP025394.1|WP_104819441.1|7453957_7455181_-|MFS-transporter
MQTLDPPRIEAPPWRDRRFRVFALGNFVNNLGESAYKVGLPLYLYQLTGSLAVISWTAALAPAVLLVSPWVGALVDRWGARPFVVPGLLVQVIGAVGLNLCLLGGRVSLGVLFPLAALVQFGGELYRCGWITGVRGMFPANPGRSRAVLSSLFTASNIAGPLLVAGGLGLVGYQGLLWFDAATFLAPIAVWLLGVHPPAKAGAAAATRPGLGRELLDGWRVIRAEREVLHAELASVPLQFVSGVGLLAFLVWYLRSELGASTGTVSLTQGLANLGALAGSAYVAGRAGLRPQRVLAVAAVVMTAAPLLMAFAPTPVLALCLTAFLAARSALTATTAALTTGRLPAEVLGRAEGLFNLVTGLPLLLAPLLIPLAQQRFGPTAVFLLLGGTAALALPLVARRRPEARSQ
>NZ_CP025394.1|WP_104819442.1|7455342_7455603_+|hypothetical-protein
MTLLLILVSGVSCAIGTLRLIADPPARLTAPLLCAAIALVTVVGADGLDHLGAGIAARTEARYAYALDSDCQYPRPSYDETPGWFF
>NZ_CP025394.1|WP_158702456.1|7455572_7456232_-|hypothetical-protein
MRFAIGLVMLDSAARHQLRVRRRCGVWRYRELMGHAFVLPRARRRVFQWGLRRCARRARVADLVELLDYGWRERLVAGWLIAAGGRNELRPRLAQELSDPEPQAQLDSYCVALACLGTEQDARILRDHLVKSLALAVEGREEHRRCRAAAMGALLYLDQRLGTDYSGPLLTEGGPWARWPGSSGTSVEEEKQEIATAVAFACGADPAPRSQKNQPGVSS
>NZ_CP025394.1|WP_104819444.1|7456402_7457068_-|hypothetical-protein
MELLPDEDPLGGLRPLLEGSGAALGYEPQEGFADRCWVLHAVTVQSRRARWDEVVAHAGRRLADWQYTPSFRVFEGLDLPEGLEGPELGEIDRGSLDSLIAVLARHSPDGLRTDCYWTQAWIEDVGSPIPARRGRLDEALAHHDASTGPARTISTQFPAHWWPVAGSWFVLTNWGLSATEVFGPAALIADLLADDGLDAVRHPSIAEVEGGSARWRDAPTG
>NZ_CP025394.1|WP_104821272.1|7457250_7457832_-|DinB-family-protein
MIDEFAKDNLHGRLRRDREALLWKLDGLSEYDVRRPLTATGTNLLGLVKHVATVEARYFGEVFDRPSPEPLCRWQDSNGSDLWATEDETRNQIIGFYRRTWEHADATISALPLNAPGHVPWWAEPAPNTNLFAVMVHVLSESVRHAGHADILREGLDGRTGLRAEHENQIDEEARAAYCAKIEQAARSAAPII
>NZ_CP025394.1|WP_104819445.1|7458056_7458947_+|metal-dependent-hydrolase
MSQSVEPTRVHESLVLEPRDVHFDWGQLPLHWIPDEPMATHTINVLHLLLPEGERWFVRLFKQALPMVTDEQLREEVLGFIGQEAIHAEAHQEVLDHLLGQGLDPRPYIAQVSWLFHRVLGDRPELSPLQQREHVIERVAAVAAIEHFTAFLGNWILNSPGLDRAKADPTMLDLLRWHGAEEVEHRSVAFDLMRHLDPGYLRRMRGMAIAGPVLFHLWVRGVRFLMAADPSLRGREKPTWREAQAVARRGLLPEPGRMARSALRYFRPGYHPTHEGSSSQALSYLATSPAARAAAH
>NZ_CP025394.1|WP_174805590.1|7459167_7460238_+|oxidoreductase
MDLQSPPPDLYGRPRADRFIQRLTAFSDWYNPLVARRAVPRPTAVQGATAVQLVVVRHEVVADGVVELRLASPYGEVLPAWQPGGRVQLILPSGRKRHYSLCGDPADRHGYRIAVRRIEGGGGGSVEVHDELFVGARLAARPPRNGFAFCGEGAVLLLAGGIGITPLLPMAYEARRRGLDWQLVHTGRDAASMPFAAELKALDPRRVVLLNDAEHGVPEAAELIAAGPKGAAVYCCGPAPMLAAVRAATPGDRPLHFERFGAAPITDGHPFTVQLGEEGPMAEVPADRSALDVLRELRPDLPYSCHQGFCGTCEVRVKAGTPEHRDRRLTAEDRAAGLLLPCVSRAAEGETLVLDL
>NZ_CP025394.1|WP_104819447.1|7460249_7461095_+|aminopeptidase-P-family-protein
MSKSFAFDEHDLDRFRETQQLAYACAEQVAAWIEPGVTERQATAKLRSCLVAAGVQDFFHVPFAWFGDRTAFRHFHTPLQFFAGGKVLEEGMPYVLDCAPVVDGYTADIGYGGKVGENRIWDRLAADLQVYRELILREVKARKPLNEVYAAVDAQIAAHGYDNRHQVYPGRVIGHQVTRNTARGPAGVNLFGFGVRTLQTLGRELISERLHGRSPLWADGKSSRHAPTPGLWAVEPHIGFREVGIKFEELLVVTEDDAFWLDDDLPHVRRWAAQPIEELTR

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP025394_4	4.3|1767169|21|NZ_CP025394|CRISPRCasFinder	1767169-1767189	21	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5159291-5159311	2	0.905
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1166725-1166751	4	0.852
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	965654-965680	4	0.852
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3402564-3402590	4	0.852
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NZ_LR594691	Variovorax sp. WDL1 plasmid 3	205997-206023	5	0.815
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	853779-853805	5	0.815
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	MN234174	Mycobacterium phage Efra2, complete genome	56045-56071	5	0.815
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	MN234165	Mycobacterium phage Yunkel11, complete genome	55727-55753	5	0.815
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	MF140416	Mycobacterium phage LastHope, complete genome	55838-55864	5	0.815
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NZ_CP022193	Yangia pacifica strain YSBP01 plasmid unnamed3, complete sequence	53318-53344	5	0.815
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1363516-1363542	5	0.815
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	256600-256632	5	0.848
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NZ_LR134468	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence	80648-80674	6	0.778
NZ_CP025394_1	1.1|383538|27|NZ_CP025394|CRISPRCasFinder	383538-383564	27	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	742719-742745	6	0.778
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	196479-196511	7	0.788
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1071231-1071263	7	0.788
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NC_008759	Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence	145880-145912	8	0.758
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP021216	Sinorhizobium meliloti RU11/001 plasmid pSmeRU11d, complete sequence	76874-76906	8	0.758
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP051470	Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence	28215-28247	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP015290	Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence	12586-12618	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP030273	Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence	58481-58513	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	CP047033	Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence	52152-52184	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP047039	Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence	52136-52168	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP015213	Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence	95951-95983	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_LR134460	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 18, complete sequence	11243-11275	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NC_011960	Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence	81313-81345	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	CP036421	Rhodobacter sphaeroides strain HJ plasmid unnamed1, complete sequence	36907-36939	9	0.727
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NC_009040	Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence	12807-12839	9	0.727
NZ_CP025394_2	2.1|474339|35|NZ_CP025394|CRISPRCasFinder	474339-474373	35	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	210692-210726	10	0.714
NZ_CP025394_13	13.1|6254606|33|NZ_CP025394|CRISPRCasFinder	6254606-6254638	33	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	208189-208221	10	0.697

1. spacer 4.3|1767169|21|NZ_CP025394|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 2, identity: 0.905

ccagccgtcaccgtcggcggt	CRISPR spacer
gcagccgtcaccgtcggcggc	Protospacer
 *******************.

2. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.852

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
accagctcggcgaacagcgcgaccacg	Protospacer
. ********** * ************

3. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 4, identity: 0.852

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
accagctcggcgaacagcgcgaccacg	Protospacer
. ********** * ************

4. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.852

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
gcctgctcggcgtagagcgcggcctcg	Protospacer
* * *****************.** **

5. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NZ_LR594691 (Variovorax sp. WDL1 plasmid 3) position: , mismatch: 5, identity: 0.815

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
acctgctcggcgtagagcgcgcccagg	Protospacer
. * ***************** *** *

6. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 5, identity: 0.815

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
ggcaggtcggcgaagagcgcgaccatc	Protospacer
*.*** ****** ************. 

7. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to MN234174 (Mycobacterium phage Efra2, complete genome) position: , mismatch: 5, identity: 0.815

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
cgcagctcggcgtcgaccgcgaccaag	Protospacer
 .*********** ** ******** *

8. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to MN234165 (Mycobacterium phage Yunkel11, complete genome) position: , mismatch: 5, identity: 0.815

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
cgcagctcggcgtcgaccgcgaccaag	Protospacer
 .*********** ** ******** *

9. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to MF140416 (Mycobacterium phage LastHope, complete genome) position: , mismatch: 5, identity: 0.815

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
cgcagctcggcgtcgaccgcgaccaag	Protospacer
 .*********** ** ******** *

10. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NZ_CP022193 (Yangia pacifica strain YSBP01 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.815

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
gccagcgcggcgtagagcgcggccaga	Protospacer
* **** **************.*** .

11. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 5, identity: 0.815

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
aacagcgcggcgtagagcgcgatcgca	Protospacer
.***** ***************.*.*.

12. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.848

ggggcgggggcggccggcggcgggaagggcgcg-	CRISPR spacer
gtggcgggggcggccggcggcagg-acggcgctc	Protospacer
* *******************.** * *****  

13. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NZ_LR134468 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence) position: , mismatch: 6, identity: 0.778

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
ccgcgctcggcgaagaccgcgaccacg	Protospacer
    ******** *** **********

14. spacer 1.1|383538|27|NZ_CP025394|CRISPRCasFinder matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 6, identity: 0.778

gacagctcggcgtagagcgcgaccacg	CRISPR spacer
agcagcgcggcgtagagcgcgatcagc	Protospacer
..**** ***************.**  

15. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 7, identity: 0.788

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
ccggcggggccggccggcgccgggaaggtgacg	Protospacer
  ******* ********* ********  .**

16. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 7, identity: 0.788

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
ggggcgggggtgtccggcggcggggcctccgcg	Protospacer
**********.* ***********.    ****

17. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NC_008759 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence) position: , mismatch: 8, identity: 0.758

ggggcgggggcggccggcggcgg-----gaagggcgcg	CRISPR spacer
ggtgcggcggcggccggcggcgggccatgaagt-----	Protospacer
** **** ***************     ****      

18. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP021216 (Sinorhizobium meliloti RU11/001 plasmid pSmeRU11d, complete sequence) position: , mismatch: 8, identity: 0.758

ggggcggg---ggcggccggcggcgggaagggcgcg	CRISPR spacer
---tcaggtttggcggacggcggcgggatgggcgcc	Protospacer
    *.**   ***** *********** ****** 

19. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP051470 (Rhodobacter sphaeroides strain CH10 plasmid pRspCH10A, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

20. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP015290 (Rhodobacter sphaeroides strain MBTLJ-20 plasmid b, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

21. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP030273 (Rhodobacter sphaeroides 2.4.1 plasmid pA, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

22. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to CP047033 (Rhodobacter sphaeroides strain DSM 158 plasmid pEA, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

23. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP047039 (Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pEA, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

24. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP015213 (Rhodobacter sphaeroides strain MBTLJ-13 plasmid b, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

25. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_LR134460 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 18, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gtcacacgggcggccggcggcgggaacgccgaa	Protospacer
*  .*. ******************* * ** .

26. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NC_011960 (Rhodobacter sphaeroides KD131 plasmid pRSKD131B, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

27. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to CP036421 (Rhodobacter sphaeroides strain HJ plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

28. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NC_009040 (Rhodobacter sphaeroides ATCC 17029 plasmid pRSPH01, complete sequence) position: , mismatch: 9, identity: 0.727

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
gaccgccgcgcggtcggcggcgggcagggcgcg	Protospacer
*.     * ****.********** ********

29. spacer 2.1|474339|35|NZ_CP025394|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.714

agtggccggccagggacgggacgagggacaggtac	CRISPR spacer
tcaggccggcgaggaacgggacgagggacaacagg	Protospacer
   ******* ***.***************.  . 

30. spacer 13.1|6254606|33|NZ_CP025394|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.697

ggggcgggggcggccggcggcgggaagggcgcg	CRISPR spacer
ctcggcagggcggccggcggcgtgcagggcgtt	Protospacer
   *  .*************** * ******. 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	884712 : 1006869	89	Klosneuvirus(10.53%)	protease,transposase,bacteriocin	NA
DBSCAN-SWA_2	1353930 : 1416764	50	Bacillus_phage(22.22%)	transposase,tRNA	NA
DBSCAN-SWA_3	3814792 : 3823699	14	Streptomyces_phage(50.0%)	NA	NA
DBSCAN-SWA_4	8433009 : 8474425	35	Thermobifida_phage(25.0%)	transposase,integrase	attL 8452440:8452457|attR 8474910:8474927

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP025394|884712:1006869|DBSCAN-SWA
CGTGGCTGAACGCGTGCAGGTTCGTGAGATCGATGACGACGAGGGCAGACGGCTGCTACGGATCGTCCGCCGGGGCACCGGGTCGGTGGTGACCTGGCGCCGGGCCCAGATGGTGCTGCTGTCCGCCCAGCGCATGCCCGTGGCGAAGATCGCGGAGGTGACGTTCACCAGCGCTGACCGGGTCCGCGACGTGATCCACAACTTCAACGCCGACGGCTTCGACTCGCTCTACCCGAAGTACCGGGGCGGACGGCCGAGGACGTTCACGCTGCCCGAGCGGCGCGAGATCAAGAAGACCGCCAAGTCGAAGCCGGCCGAGCACGGCCTGCCCTTCTCGACTTGGAGCCTGGCCAAGCTGGCCGACTTCCTGGTCGCAGAGGGGGTGGTCGACGACATCAGCCACGAGGGCCTTCGGGTCCTGCTCCGCGAGGAGGGCGTCTCGTTTCAACGCGTGAAGACCTGGAAGACCTCCCGCGATCCCGACTACGCGGCCAAGAAGGCTCGGGTCGAGCACCTCTACGCTATCGCCGACGGCGAGGTCGTACCCGAGGATGGCGAGCCCGAAGTCGTGTTCTGCCTGGACGAGTTCGGGCCGCTCAACCTCCAGCCCCATCCCGGGAAGCAGTGGGCCGAGCGCGGAGGCCGGCACAAGGATCCTGACCGCGAGCCGCGGCCGAGGCGGCGGGCGACCTACACCCGCCCGCACGGGGTCCGGCATCTGTTCGCCGCCTACGACCTCGCCAAGGATCAGCTCTACGGGCACGTCAAGAAGACGAAGAATCGGTCGAGGTTCCTGGAGTTCTGTCGCTACCTGCGCTCGCTGCACCCGGCGGACGTGCGGATCGCGATCGTCTGCGACAACTACTCGCCGCACCTGACGACGAAGCGGTGCCAGCGGGTCGGGACGTGGGCGGCGGCGAACAACGTGGAGATCGCCTATACCCCGACCAACAGCTCCTGGCTCAACCGGATCGAGGCCCAGTTCACCGCCCTGCGCTACTTCGCCCTCGACGGCACCGACCACCCCAGCCACAAAGCCCAGGGCAGCATGATCCGCCGCTACATCATCTGGCGGAACAAGCACGCCCAGGACGAGCGCCTACGCAAAGTCGTCACCAGGGCGAACGTTGCCTGATGCGGCACTAGGGCACGTATCGGGTTGTGATCACTTTGTGGGTTTCGCCCTCGCGCTCGTGCCTGATCCGGTAGATCGTGTTGTGTGACGCGTGTGCAACTGACCGATGCCGAGTGGGAGTTCATCGAGCCGTACCTGCCGATCGGCGAGTACGGCCCGTACCCCGAGCGGCTGCGCCGCCAGTTCGAGGGCGTGATCTGGCGGTTTCGGACGGGCGGCCAGTGGCGGGAGATGCCGAGCGAGTTCGGCGCCTGGTCGACCGTCCACAACCGCTTCCGGCAGTGGAGGGACGCCAGGGTGTTCGAGGCCCTGCTGGAGGGCGCGATCACGGAAGCCGCCAGACGGGGCGAGGTGGACCTCTCGCTGGTCAGCGTGGATTCCACCACCATCCGGGCCCACCACGACGCCGCCGGGATGCACCTTGACCCCGACACGCTCGCCGACCTGGAGAAGGCCGCCGAGGAGGCGGAGAAGGCCCGGCAAAAAGGGGCGGCCCGCAGGGACAAGACGGACAGGACACCGCACACGACCCGGAACGGGACGAGCTCCGACGCGTCCGACGCAGGCGAAGGCTCCGCCTGAAGGCCGCCCTGCTCGGACGCTCCAGAGGCGGACAGACCAGCAAGGTCCACGTCGCCGGCGAGCGCAGGTGCCGCCCGCTGGCGTTCATTCTGACCGAGGGGCAGGCCGCCGACAGCCCGCAGTTCATCCCCGTCCTGGAGAAGGTGCGGGTCCGCGGGCCCGTCGGCCGCCCCCGCACCCGGCCCGACGCGGTCGCCGGGGACAAGGCCTACTCCTCCCGCGCCAACCGCGCCCACCTGCGCGGTCGCCGTATCAAGGCGGTCATCCCCGAGAAGAAGGACCAGGCCGCCAACCGGAAGAAGAAAGGCAGCAAGGGCGGCCGGCCCGTCAGCCACGACACCGACCTCTACAGGGAGCGGAACACCGTCGAGCGCCTGATCAACAAGCTGAAGGCCTGGCGAGGCATCGCCACGCGATACGACAAGACCCCCGGCAGCTACCTCGCCGGCCTCCACCTCCGCGGCGCGATGATCTGGATCAAAGACCTCACCAAAACCGCCCCGTGATCACAACCGAATACGTGCCCTAGGTCACCCTCCGTCAGCCCGGCCAACCGTTAAAAACCGCCGAACCCCTAAAGCTGCGGCAGCTCCGGCCGTTCCAGCCAGGCCTCGAAGAGCGGCCCGAGCGGGGTGGCGGTGTACCGGGCGGCGTGCGCCACCAGGTCGGCCGTGCCGACCACCCCGTGCCGGTTGAGCTCGGCCCAGCCGCGCAGCATGGCGAAGAAGGGCTGCTCGCCGAGCGCCAGCCGCAGCGCGTGCACGGCCAGGCCGCCGCGCTGGTAGAGCCGGTCGTCGAACATCAGCTTGCGGCCCGGGTCGGCGAGCACCAGGTCCTGCGGCAGCCCCGCGAGCAGGCGGTGCGCGGCAAGGGCGTGGCTGGCCGCCACCGGGCCGCCGGCGTGCTCGGACCAGAGCCACTCCGCGTACTTGGCGAAGCCCTCGTTCAGCCAGATGTGCCGCCAGTCGGCGATGGTCACGCTGTTGCCGAACCACTGGTGGGCCAGCTCGTGGGCGATCAGCCGCTCGCGCTCCCAGCCGCCGCCGAGGTGGTTGGTGCCGAAGGTGGCCACGCCCTGGGCCTCGACGGGGACGTCGAGCTCCTCGTCGGCGATCACCACGGCGTACTCGCCGAACGGGTAGGGGCCGAAGACCTCGCCGAAGTAGGCCATCATCTCCGGCTGCCGGGCGAAGTCCCGGGTGAAGGCGGGCACCAGCCGGTCGGGCACGTAGCCGGTCTGCGGCACGGCCGGGCGGGCGGCCACCGGCACCGGGCGGTAGTGGCCGATCGAGACGGTGACCAGGTAGGGCGAGGTCGGCGCGCTCTGCTCGTAGACCCAGGTGGTGCTGGAGGCGCGGGTGGTGCGGGTGAGCAGCCGGCCGCCCGCGAGCACGGTGAACGGGGAGGGGGTGGTGACCTCGATCTGGTAGGTGGCCTTGTCGGCCGGGCGGTCGTTGCAGGGGAACCAGGACGGCGCGCCGATCGGCTGGCTGGCCACCAGCGCGCCCTCGGTCAGCTCCTCCCAGCCCAGGCCGCCCCACGGGCTGCGCACCGGACGCGGGTTGCCGGCGTAGTGCACCTCGACGGTGAAGGCCGCACCGGCCGCGAGCGCCTTGGCCGGGCGGATCCGCAGCTTGCCGCCCCGGTGGGTGTAGCGGGCGGCGGCCTTGCCGTCCACCAGCACCCGCCCGATCCGGAACTCGGCCAGGTCGAGCGCGAACTCCTCCAGCGCCGCGTTGGCCACCGCGCTCAGCCGGGCCTTGCCGCCGAGCCGGTTCGGGCCGGGCTGGTAGTCCAGGGTGAGCTCGTAGCGGTGCACCCGGTAGCGGTGGTCGCCGCTGGTCGGGAAGTACGGGTCCGGGGTGCCGGCGGCCGCCGGGGCGTGCTTGGACTTCACGGGGGCGGGGGCTTCCTGCGGGCCGGGGTCGGTGGTCGTCACGTGGTCTGCCAGGCCTCGATGGGGTTGCCCAGCCACCGCGTGTCCGCGGGGACGGACTCGGCTCCCATCACCAGCGAGGCCGGGCCCAGCGTGCTGCGCTCGCCCACCGTGCTGCCGGGCAGCACGATCCCGCCCGGGCCCAGGGTGGCGCCCTCGCGGAGGACCACAGTATCCATCCTCATGATCCGGTCGTGGAAGAGGTGGGTCTGCACCACGCAGCCGCGGTTGATGCTGACCCCGTCGCCCAGGGTCACCAGGTCGGCCTCGGGCAGCCAGTAGCTCTCGCACCAGACGCCCCGGCCGACCCGGGCGCCCAGCGCGCGCAGCCAGAGGTTCAGCACCGGCGTGCCCGGCACCGCGCCGACCAGCCACGGCACCGCGAGCACCTCCACGAAGGTGTCGGCCAGCTCGTTGCGCCAGACGAACCCGCTCCAGAGCGGGTGCTCCACCGCGCGGAACCGCCCGACCAGCACCCACTTGGCCACCACCGCGACCAGGCAGGCCACCGTGCCCGCCGCCAGCAGCACCAGCCCGGAGACCAGCGCGGCGACCAGCGGCGACCAGGCGGCGCAGACCCGGGCCAGCACGGCGGCGGTCACCAGGCCGAGCGCGCCGGAGGCCAGCACCGGCAGCAGCCGGCCGACCTCCACCAGCCCGCGGGCCCAGAGCAGCCGGGCCGGCGGCTCGTAGGTGAGGCTCTGGTCGGCCCGGTCGGCCGCGCGCGGCAGCTTCATCGGCGGCATGCCCAGGTACGAGCTGCCCTTCTTGGCCTTCTCCGGCGTGGCCGAGAGCACGCCCACCAGGCCCCGCTTGGGCACCGAGCGGCCGGGCGCGGTCATCCCCGAGTTGCCCAGGAAGGCCCGCTCGCCCACCTTCGCCTCGCCGAGCCGCACCCAGCCGCCGCCCAGCTCGTACGGGGCCATCAGGGTGTCGTCGGCCAGGAAGGCGCCGTCGCCCACCGTGGTCAGGCTGGGCAGCGCGAGCACCGTGGAGACCTCGGCGCCCCGGCCCACCTTCATGCCCAGCGCCCGCAGCCAGTACGGGGTGACCAGGCCCGCGTACAGCGGGAAGAGCACCTCGCGGGCCTGGTCCATCAGCTGGGTGACCGTCCAGGCCTGCCAGCCGACCCGGCCGTGCACCGGGTGCACGCCGGTGACCAGGCCGAGGCTCAGCACCCGCACCAGGGCCACCAGCTGCGCCGCGTACACCGCGCCGAAGGCCAGCGTGGCGGGCAGCAGGCCGAGCAGCGCGCCGCCGAGCGCCTCGCCGAGCGGGGCGCCCTGCGGGACGACCAGCGCGAGCACCGCGAGCGCGGCCAGGCCGGGCAGCACCGGCAGCAGGCTGAGCAGGGCGCCGCCCGCGCCGTACAGCGCGGCCCAGCCGGCCCGGCGCGGCGCGCGGGCCTTGGGCCAGAACCGCTCGGCCCGGCCCAGCTTCACGGCCGGGGCGCCGCCCCAGCGCTGACCGGTGGGCACCTGGCCGGTGACGCTGGAGCCGGCCACCACTTGGGCGTTCTTGCCGACCTTGGCGCCGGGCTGGAGCGCTGAGCGGGTGCCGACGGTGGCGCCGGAGCCGACCTTGAGCGGGCCGACCTCCAAGCGGTCGCCGTCCAGCCAGTAGCCGGAGAGGTCCACCTCGGCCTCCACCGCGCAGCCCCGGCCCAGCTTGAGCATGCCGGTGACCGGCGGCAGCGAGTGCAGGTCGACCTCGGGGGCCACCTTGGCGCCCAGTGCCCGGGCGTAGCGCACCAGCCAGGAGCCGGAGAGCGCGGTCGCCCCGGTCACCTCGGCGAGGCGCTCGGCCGTCCAGAGCCGCAGGTGCACGCTGCCGCCGCGCGGGTAGCTGCCGGGGCGCAGGCCGCGCAGCAGCAGCCGGGCACCGCCGGCCGCGAGGGCCAGGCGGCCGGGCGGGGAGTACAGCGCCAGCGCGCCGGCGCCGACCGCCCACCAGGAGGCGGTGGGCGCCCAGGGGAAGTCGCCGAGGTGGGTCAGCAGGTTGCCGGCGGCCAGCAGGGCCACCGTCCAGCGCAGGCCGACCACGGTGAAGAGCGGGATCAGCAGCAGCAGCTGGAGCAGCTTGGCCTTGGCGGGCACCAGGGCCACCGTCCGGGCCTCGCCGCTCTCGGCGCCGGAGCCCTCCAGGTGCCGGGCCAGCTTGCGCAGGGTGGGCTGCTGGTAGATGTCGAGCACCGCGACGTTGGGGTAGCGGGTGCGCAGCAGGGTGGTGAGCCGGGCGGCGGCCAGGCTGCCGCCGCCGATGGCGAAGAAGTCCTCGCGCGGGCCGCTCACCTGGACGCCGAGGATCTCGGCCCACTGCTCGGCCAGCCAGGCCTCGGTGCCGTAGAGCTGCTCGCTCGGCCCGGCGGTCTCCAGCTCGGGCAGCGGCCAGGGCAGGGCGCCCCGGTCCACCTTGCCGGAGGTCCGGGTCGGCAGGGTCTCCACGGGGGCCAGCAGCGGCACCAGCGCGGCGGGCAGCTCGGCCCGCAGCCGCTCCACGGCCTGCTCGCGGTCGAAGCCGTCCTGGATCACCAGGTAGCCGACCAGCAGCTGGTTGCCGCCGCGCGCCGTCCGCACGGCCGCCGCCGCCCCGGCCACGCCGGGCAGGGCCTGCAGGGCCGCGTCCACCTCGCCGAGCTCGATCCGGCGCCCGCCGAGCTTGATCTGCTCGTCGGTGCGGCCTAGGAAGAGCAGCCCGGCCGGGTCGGCCTGCACCAGGTCGCCGCTGCGGTAGGCGCGCCGCCAGCCGAGCGAGTCCAGGGGGGCGTACTTCTCGGCGTCCTTCTCCGGGTCCAGGTAGCGGGCCAGGCCGACCCCGCCGATCACCAGCTGGCCGGCCTCGCCCAGGGCCACCGGCTCGCCCGCCTCGTCCACCACGGCCAGGTCCCAGCCGTCCAGCGGCAGGCCGATCCGCACCGGGCCGTCGCCGGTGAGCAGCGCGGCGCAGGCCACCACGGTGGCCTCGGTGGGGCCGTAGGTGTTCCAGACCTCGCGGCCTTCGGTGACCAGGCGCTGCACCAGCTCGGGCGGGCAGGCCTCGCCGCCGAAGATCAGCAGCCGGACCTCGTTGAGCGCCTCGGCCGGCCAGAGCGCGGCCAGGGTGGGCACGGTGGAGACCACGGTGATCTCCTGCTCGGCCAGCCACGGGCCGAGGTCGGCGCCGCTGCGCACCTGCGAGCGGGGCACCGGCACCAGGCAGGCGCCGTGCCGCCAGGCCAGCCACATCTCCTCGCAGGAGGCGTCGAAGGCCACCGAGAGCCCGGCCATCACCCGGTCGCCGGGCCCGATCGGCTCCTCCTGGAGGAAGAGCGCGGCCTCGGCGTCCACGAAGGCGGCGGCGTTGCCGTGCGTGACGGCCACGCCCTTGGGCTTCCCGGTGGAGCCGGAGGTGAAGATGATCCAGGCGTCGTCCGCCACACCGGGACGGCGGGCTTCGGCGGCCGGGCGCTGTGCCGTGACCTCGAGCGAGCGCTCGGCCCCGAGCACGGCGGCCACCTCGGCCTCGCCGAACACCAGCTGGGCCCGCTCTTCCGGGTCCTCGGCGTCCACCGGCACGTACGCGGCCCCGGCCGCCAGCACCGCCAGGATCGACACGTAGAGGTCGTTGGTCCCCGAGGGCACCCGCACCCCGACCCGGTCGCCCGCGCCGATCCCGGCCGCCGCCAGCCGCCGCCGCAGCTGCTCCACCTCGGCGGCCAGCGCCCGGTAGGTCAGCACGGAGCGCCCGTCGTCCAGCGCCGGCTCGCCCGGGTGGTCACGGACGGTGGCCTCCAGCAGGTCGACCAGGGTGCGCGGTACGGCGGCCGGGCGGCCCGGGAAGAGCGCACGCTGCGGCAGGTTCGGTTCGGCTGTCATGGCGCCCATCTGCTCCTCGCTTCGGACAACCCGACCGATGCTAGCCCGGGCCCGAGCGGCCCGCCCAGGCTCCGTCAGCACCCAACTGGCCGATGGACCGTCGAATCTGACGATCAGTCAACCCACAATGCCCCTTGCGGCACGTACATCTGACGGACCGTCAATCGTTTTGACGGTCCGTCAGATCGAATCGGGAAAAGTGATCCACGCCACAGCGATCGCTGCTCCTTACGGGCGGTGCCCGCCCGCAGGGCCCGTCACCAGCCGTACCTCGGCCACCTGGGGCCATCCCGAGGGCCACACCCCGCGGACGGCGCGGCGCCAGGCCCGCAGGTCCGTGCCCGCCGTCTCCAGGGTCACCGTGGCCCGCAGCGCCCCGGCCTCACCGGTCAGCCCGACGGCGGCCGAGCGGACGCCCGGCAGGCCCGCCAGCGCGGCCTCCGCCTCGGCCAGGTCGAGCCGCCGGCCCATCCAGTCCCGCAGCTGCCCGGCCGTCCCGAGCAGCCGCACCCGACCGGCCGAGTCGATCCAGGCGCGCCGGCGGCCCACCCGCCCGTCCCCCGCGAAGGCCAGCAGCCCCGGCACCCCCTGCGGCAGCCCTCGTCCCTCGGCCGTGACCACCCGGTACCGCCGCCCGGCCACCCCGCCGACCAGCACCTCCTCCCCGCCCACCCGCAGGCCGTACCCGAGCACCCCCAGCACCTCGTCCCGCACCGCCACACCCGCCACGCCCGCCGGCACGACCACCTCCGGCCCGGCCTCGAACAGCTCCGCCACCGGCCGCCCCGGCTCCGCCGTGAGCGCCGCCAGCAGCCGTGCGTACCCCGCCGTGAACCGCCCGGCGGCGGCGCCGTCCAGCGCGAGGGTCGAGTGGTCCAGCCGCCCGTACGCCGCCCCGCCCTCCCGCCGCAGCTGCAGGGTCAGGTCGAAGGACTGGGTCGAGTTCGGCGCGAAGAAGTCCCACTCGCATGCCAGGCCCGGCACCTCGCCGAGCTCCCGCACCACCCTCGGGTACGACACCCCCACCCCGTCGAAGGCGCCCCGGGTCACGTCCACCCCGTGCCGCTGCCGGAGTTGCCGCAGCACCCAGCCGAACGGCACCCGCCGGTACCGCTGCACCAGGGCCAGTGCCCGCCCGCTCACGGCCAGCAGATCGGTGAAGCTCGCCCCGGCCGGGATGTCCAGCAGGCAGGGCACCACGTTCACCTGGAGACCGATCTGCTCCCGGGTGCCCGGCTCGCTGGTGTCAGCCGGGATGCCGAGCACGAAGCGGGTGTTCCCGTACTCGTGCAGCCGCGCCGCCACCCCGGCCACCAGCCCGGTGAAGAAGCTGACCCCGGCGGCCCCGGTCAGCGCGGCCAGCCGGGCGCAGGTCTCGGCGGGCAGCTCGAACCGGGGCGTCGGCTCCACCACCCGGCCGCCCGCCGGCAGCGGGCTCTCGCGGCGCGGCAGCACCAGGCCGGGCAGGTGCGGCAGGTCGGCGGCCAGCCAGTGCTCGACCACGGCCGCCGCCTCGGCGTCGATCGACGGGTGCTCGGGCAGCGCCACCGGCTCCCGCTCCCGCAGCCCCGCCGGCGAGCGGAGCTCGCCGAGCGCCTGCAGGAAGCGGCGGGCGAAGACGAACTTCGACCGGCCGTCGAAGGCGATGTGGTGCACGGCGACCACCAGGGTGCGCCGCTGCCCGCCGTGGTCGAGCAGGGCGAAGGCGATCGGCGGCTGCTCGGTCAGCCGCCAGGGCCGCAGCCGGTGCGTGCGGTGCCACTGCCTGGCGACCGTCAGTTCCGCCCCCGGCGGGGCCGGCACCGCCACCGTCTCGAAACGGAGCACCCGCTCGGCCGGGTGCACGGCGATCCGCGCCGGGCCGCCACCCTCCCCCGGCACCACCAGTCCGCGCAGCTGCGGGCTCTGCGCACAGACCGCCAGGCAGGCGGCCCGCAGCTGCCCTGCCGTCACCGGACCCCGGACCAGCACCGAGAAGATCCCGCCGTTGACGCTCTCGGGGTGCAGCAGTTGGTCCAGCCACATCGACTCCTGCGCGGGCGAGAGCCCCACCAGCACCGGCTCGGATGAAGACTCGGGCTCAGCGGATGGGGGTCCCGGTGCCGTCGAGTTCACGTCGCGCCACCTTCCCGCTGGCCAGCAGCGGCAGCTCGGCCACCCGCAGGAAGCGGGCGGGGATCATGTACTCGGGCAGCTCGGCCGCGCAGGCGGCCCGCAGCGCGGCGGCGTCCGGGCCGGCCGCGGCCGGATCGAGCACCAGGTAGCCGTGCAGCGTGGTCGACCCGGCCCGGCTGCGGCCCACCACGGCCGCCCGCCGCACCCCGGGCAGCCGGCTCAGCACGGCCTCCACCTCCCCGGGCTCCACCCGGTAGCCCCGCACCTTCAGCTGGTCGTCGCCGCGCCCGAGGAAGTGCAGCAGACCGTCGGCCAGCCGCACCCGGTCGCCGGTGGCGTACACCCGCCGCACCACCCCGTCCCAGCCCGCCACCTCGCGGAACCGCTCCGCCGTCAGCCGCTCGTCCCCCAGGTAGCCGAGCGCCAAGCACCGCCCCGCGACCAGCAGTTCGGCCTCCTCGCCCTCGGCGAACGGCCGCACCAGCCCGCCGTCCTCACGCAGCAGCTCCGCGCCGACGGCCGGGCCGCCGAGCGCGGGGTGTGCCGGCCAGCCGGCCGGGTCGCCGCTCAGCCGGTGCTCGGTCACCAGGTGGGTCTCGCTCGGGCCGTAGTGGTTGACCAACTCCGCGTCCAGCGTGGCGAACAGCGCCCGCACCTCGGCGTTGACCACCAGCCGCTCGCCGGCCACCACCACCTCGCGCAGGGCGGGCAGCCGCCGGCCGGTGGCGGCGCAGGCCACGGCCAGCGCGTGCAGGCCGGTGACCGGCAGGAAGCTGCGCACCACCCCGTGCCGGTGCAGCAGCTCGGCCAGCAGGAAGGGGTCGCGCCGCTGCTCCTCGTCGGCCACCACCAGGGCCGCCCCGGCCACCCAGGTGGCCACCAACTCCTGGTAGCCCACGTCGAATCCGACCGAGGCGGCATGGCTGGTCCGGGGCAGCTCGGCGCTGCGCCAGCCCGCGCAGTGCCACTCGGCGAGATCGGCCAGCACCACCGTGGGCACCGCCACGCACTTGGGGTCACCGGTCGAGCCGGAGGTGGTCACCACGTACCCGAGCGGTCCCTCCTCGGTCAACTGCGCACCACGCAGCAGCACTTCGCCGATCTCGACCTCCGGCACGCCGTACCCGCCCGGCGCCACCCCCGGCCCGCGCAGCACCAGCGCCGTGCCGGAGAGCTCCACCACCCGGGCCGCCCTGGCCGCCGGCTGGGCCGGATCCAGCGAGTTGACGGCCGCCCCGGCCCGCCAGATGCCCAGCACGGCCGCACAGCGCCACCACCCGCGCGGCGCCAGCAGCCCGACCGCCTGCCCCGGCCGGACCCCGCGCGCGGCCAGCCCGGCCGCGATCTCCCCGGAGAGCCGGTCGAGTTGCCAGTAGCTGTACGCCGCCTCCCCCTCCACCACCGCGACCCGCGCGGGGTGGGCCGCACAGGTGGCCACCAGCACGTCCACCAACGACCAGGCCGGCCGCACCTCCACGCTCCCCGTAGCCACGGCCACCACCGCCCCTTCCGCGCTCACCGCGCTCCCGGCACTCACAGCGCCACCGTCACGCCCGAGGAGAGCCAGTGGTGCAGCTGGATCGCCGCCTCCACGCTCATCCGGGTCACCCCGGCCCGCAGCCCGAACGTCGGGTCCTCCAGCGCGGCTTCGACCCGCCCCGCGTCCAGCAGCTCGTTCACCGGTGCGTCCTTCTCGGCCCGGATCGCCCGCAACTGCTCGCGCAGCGCGACCCGGTAGGCCGGGTCCTGCACGGTCGGGTACGGCGACTTCTTCCGTTCGAGCACCGCCGTCGGCAGCAAGTCCCGTACGGCGGCCCGCAGCAGGCTCTTCTCCCGCCCGTCCGCGACCTTCATCGCCCAGGGCACGTTGTAGACGTACTCGGCGAGCTCGTGGTCGCAGAACGGCACCCGGCCCTCCACCGAGGCGGCCATCCCGAGCCGGTCCTTGCGGTCGAGCACCACGCGCAGGTAGCGGGTCATGTTGAGGTAGGTGAGCTCGCGCATCCGCCGCTCCGCCGGGCCCTCCTCCCCGGTCAGCGGCACCTCGGCCAACGCCTCGCGGTAGCGGGCCCGTTCGTGGCCGGGGAAGTCCAGCGCGGCGTACAGCCTGCGGTCGAGCAGCCCGGAGAGGAACTCCATCCGGTGCGAGGCGCCGAGCCAGGGGAAGGTCTCGGCCCGCACGTAGAACGGGTCGTGGAACCAGACGTAGCCGCCGAAGAGTTCGTCGGAGCCGTCGCCGGTGAGGGTGACGGTGGAGTGCCGGCGCACCTCCTGGGAGAGCCGGTACAGCGAGACGTACATGTCCAGGCCGGCCGCCGGTCGGTCCATCGCGCGGACCACCTCGGCCTGCGCCTCCGGGTCGGTGAGCTGGGCCTGGTCGACCAGCAACTCCCGGTGCTCGCTGCCCAGATGGGCCGCCATCCGGGCCACGTACGGGGCGTCGGCCGAGTCGTGCACCTCGTCGGGGCGGAAGTGGTCGAGGTGGTAGGCGAACTCCATCGAGAAGGTGCGCAGCGGCCCGCCGACCACCTGCCGGGCCAGCGCGCAGACGGCCGAGGAGTCCAGGCCGCCGGAGAGCATCGAGGAGATCGGCACGTCGGCGGCCACCTGCCGGTCGACGATGTCCTCGAGCAGCGCGCGGACCCGGCGCTCGGTGGTGGGCAGGTCGTCGGTGTGCCGGGCCGGGGTGAACTGCCAGTACCGGGCGCGGTGCAGGCCGCCCCGGCCGTAGCGGACCAGCTCGCCGGGCACCACCTCGCGCATGCCGCGGAAGACGGCGGCGCCGGGGGTGGGGGTGAAGGAGAGCGCCTCGAGCAAACCGGCGCCGTCCACCACGGGGGCGATCAGCCCGGTGGTGAACAGCGCCTTGGGCTCGGAGCCGAAGGCCAGGCCGTCCGGGGTCTCGGCGTAGTACAGCGGGTAGATGCCGAACCGGTCGCGGACCAGCAGCAGTTCTTCGCGCCGCACGTCCCAGACCGCGAAGGCGAACATCCCGCGCAGCCGCTCGGCGCAGCCCGCGCCCCACTCCTGGTAGGCCCGCAGCACCACCTCGGTGTCACTGCGATCGCGGAACTCGTGGCCCCGGCGCCGCAGTTCCTCGCGCAGCTCGACGAAGTTGAAGACCTCGCCGGTGTAGCCGAGCACCACCGTCTCGCGGCCCTCGGCGTCGGTGGCCACGGCCGGCTGGTGGCCACCCTCCAGGTCGACCACCGCCAGCCGGCGCGGGACGAACCGGGCCCGGGGCGAGCTCCACTCGCCCACCGCATCGGGCCCGCGCAGGGCGAGCGCCCCGCGCATCGCGGCGCCGAGCTCCGGGCGTTGGGCGAGGTCCGTGGTGAAGGAGACCAGACCGACGATGCCGCACATGGCGCGAGCTCCCTACCGCCGTGACGCAACGTCACGAACCTTGACCGGCCGGTTGATCGGTGACCGATTGAACAATTCACCCGCAACCCCGTCAAGGCATGCCGAAGGCCACCGGGCGTCAACAACCTGCCATCGCGGCCGGGCCGGCCGGGCGCGGATGGAGCAGGCCGATGGTGACGGCCGCGACGGCGGAGACGGTGCCGCCTAGGGCGAGGGCAGCGCGCGGCCCGGCGTCCTGGGCGATCCAGCCGATGACGGGGGCGACCAGCGGGGTGGTGCCCAGGGTGGCGAGCAGGTAGAGGCTGGTGACCCGTCCACGCATGCCCTCGCCGGCCTCCAGCTGGAGGCGGGCTTTGGCGGCGGTGAGGAACACGAGCATGGCGGTGCCCGTCGGCACCAGCAGCACGAGGAACCCGATGCACCCGGGCATCAGGGCGCACCCGGCCTCCAGCGTCCCGAAGGCCAGCGCGGCGGCGGCCAACTGCCGCCCGCCGGTGCGGGGGTGGCGGATGGCCAGGAGGGAGCCGATCACCGAACCGGCGGCCAGGGCGGTGTTGCCGAGCCCGAACACGGCGGCCGGGGCCCGGTAGACCTGGGTGATCATCAGCGCGGTGGTGATCTGGAAATTCATGCCGAACGCGGCGACGACCGCGACCAGTACCAGGGTGAGCATGATCGGGCGGTGGCCCCGGACGTACGCCAGGCCTTCCCGTACCTGCCGCTTCGCGCGGGCCACCGCCGGCGCCGGACGGACGGCCCCGGGGTCCGCGCGCAGCAGGCAGGCGATGACGACCAGGTAGGAGAGGGCATTGGCGAGGAAGGCGGGGCCGGGACCGAACGCGAGGATGAGCGGACCTGCCAAGGCCGGACCGGCCATCCGGGCCAGGTTGAGGACCGCGCTGTTGACGGCGAGGGCGCTGACCAGCTGCCCGGGGGCGACGGACTCCGCGAGGTACGCCTGCAGGGCCGGCTTGTCGACCGTCATGGTCAGCCCGAGGGCCAGGGCCAGCCCGTAGACCGCGTCCAGCCGGGCCGTGCCGGTCGCGACGAGCAGAGCGGGGATGAGGGCGAGGGCGGCCATCACCGCCTGGGAGAGCAGCAGGATGCGCCGGGTGCAGTACCGGTCGACCAGGACTCCGCCGTAGGGCCCGAGCAGCAGCAGCGGCAGGAACTGCAGCGCGGTGATGATGCCCAGGACGGTGCCGCTGCCGTGCGACAGGTGGAGAGCCAGCCAGTCCTGGGCCACCTTCTGCATCCAAGTCCCGGTGTTGGAGACCGTCTGCCCCAGGGCGAAGAGCCGGAACCTCGGGCTGCTCGGCGGCCGCCTACGACTCGGCGGACGTGGGATGCGCACGGACTGGCTCCTCGGGTCGCCGACTGGCCGGCAGCGGGCCCCCGGTGCTCCTCAGGCGGGCCCGGAAGGCGGCCACCAGCGCGGCGGGCACCCCCGCCAGCTCGGGCCGGCAGCTGACGTTGGCGTTGACCTCGCAGACCACGAACCCGCCACCGGGGGCGAACAACAGGTCGACCCCCGCGACGGCGAGCCCCATCGCGGCGGCGGCCCGGACGGCGAGCTCCTCCCCCTCGGGGTAGCGGCCCGGACAGGGCGCAAGAGTGCCTCCCAGTGCCAGATTGGAGCGGAACTCCCCCTCGGCGGCGGTCCGTACGCCCGCTGCGGCGGCGTGGCCGTCGACCACCACCACCCGCAGGTCCCGGCCGTGCGAGTGCCCGATGTACTCCTGGAGCAGGGAGGCGGTGTCCTCACCGAACCGGCCGTGCAGGGCCCGCAGCGCCGCCGGATCGGGTGCCAGGAACACCTGCTCGCCACGGTGGCCCCGCACCGCCTTCACCACGCACGGCGTCCCCAGGCTCGCAGCAGTCACCTCGTGGAGGGGAGTCCCCCCGCCCATCCGGCTCTCGGGCACCGCGAGCCCGGCCGCAACGAGCCGCTGCAGTTGCCAGAACTTGTCCTGGCAGGCCAGCACCGCGTCCGCCGGATTCAGCACCAGGCTGCCCATCGACTCCAAGTGCCGCAGCAGCGCGATCTCCCGGCCCGCACCCGCTCCGGGAGTCCGCACCCGCCCGTAGACCACCTGTGGCGCCGTCACCTCTCCGCCGTCCGAGCCGTGCAGCGAAAGCCCGCCGCGCCCGGCCCCCATCACCAGCTCCGCGCTGCGCACCACCGCGAACCGATCGCCGAACTCCCCGGCCAGCGCGGCCGTGATCCGCCGGGTGAACGGCCCCGACAGACCTGCCCCCAGCAGCAGCCACAGATCGGCCTCGCGCCTCGTCGGCACCGGACAGTCCTCACCACTGTCGGCCACGGACACCCCGACTCCTCCAGATCGACCCGGCGGGCGGACACGCCCCCGCCCCGACGATCCCCTGCCGAGCCGGGCTGCGGTGCGCGAAACGCCGTGGGCATCCCCCGGACGGCTCCCCCGTCAGGAGCCCGGCTGCTCAGTAGTAGTGCCGCAGTTGGGGCCAGAGCTGCGACCACGGCCGCGACGGACCGGCGCAGAGCACCACGGCCGCGTGCTGCTCCTGGTTGGCCACGCCCTGCCCGGTGTCCACTTCGCCCACCGGTCGACAGTCGGTGAACTGCCGTTCCACGGCGCCGAATCCGGCCGGGTGCACCAGCAGCACCGGGCCGGCCTGCCGGTCGGCGGGCGGCCCCCAGTCGGCCAGGCTCATGTGGCCCGAGTACGGCCCGGGCAGCCCGAGCCCCGGCCCGTACCGGGCCAGCGCGCCCGCCTCGCCGTAGTTGGCGGCGAACAGCACTGCGGTGTCCCGCTGTTCGGGCGGGATCTGCGCCCAGCCCCGGGCCGCCGCCGAGGCCAGCTGCGGCCAGCCGACCTGCTCGGCCGCCTCCGGGTAGATCCAGCCGACCGCCACCAGCGCCTTCGGCGGCAGCACCGGCAGCGTGATCACCACATTGACCAGCGCGCCCACCAGCAGCCCGGCCGTCACCACCCGGCCGGTGCCGCGCGGCTTGGCGCAGCCGGCCGCCATGAGCACCAGCAGCAGCGGCACCGCGTAGTACGCCTTGCCGCCGAAGCGGCTCAGCAGCCAGAGCAGCAGCGGGTAGGCGAGCGGGTAGGCCCGGGCCCAGCTCAGCTCCGGCTCCCGGCGCAGCCTTCGCGCGCCCCGCAGGACGAGCGGGACCACGGCCGGGGAGAGCAGCACGAGCTGTAGCGGGAGCAGCAGCCAGCGGTTCTGTTCGCCGTCCTTGTCGGTGATGCCGTTCGCCACCGTGAGCTGGGGCCAGCCGTGGGCCGCCTCCCAGAGCAGGTTGGGCAGCGCGACGAGCACGGCCAGCGCCAGGCCGGCCGGCAGCCACCGGCTGAGCAGTGCGCGCCGGGGCCCGGAGACGAGCACGGCGGCGAGCAGCGCGAGCCCGATCAGCAGCACCAGGTCCTTGTTCAGCAGGGCGAGCCCGGTGGCCGCCCCGAGCGGCAGCCACCAGCGGCCGTCCCCGGTGCGCAGCAGCCGCAGGCCGAGCAGCAGCACGCCGAGCGAGGCCGGCAGATCGGCCGAGCTGGTCAGCAGCAGGTGCCCGGTGGCCAGCACGAAGGCGGAGCCGGCCGTGGCCCAGGCCGCGAGCAGCTGCCCGCGCCGCTCGCCGCCGAACTCCCTGGCCAGCAGCGCGACCAGCACCACGTCCACGCCCGCGAGCAGCGCGGGCAGCACCCGCAGCGCGAGCGGGCTGTCGCCGAGGGCCAGCTCCGAGAGCCGCGCCAGCCAGGGCGTCAGCGGCGGCTGGTCCACGTACCCCCAGGCCAGGTGCCGCCCGGCCAGCAGGAAGTACAGCTCGTCCCGGTGGTACCCGTACCGCCCCGCCAGTGCGAGCAGCAGCACCACCACCCCGGCGGCCACGCCGGCCACCGGCCGCCACCCGAATCCCGGCAGCTCAATCGGCCCGGCCCTCGGCGGTATCGGCTCCGGAGCCGCAGCCGCACCGCCCTCCGTGCTCTTCCCCCGTGTGTTCATCCCGGGAGTCTCGCACCGCTCCCACCTGCACGGAAGCCCCTCGTTCGGAAACCTCCGGACGCCCGGTACCGCCCCACCGCCCCTCGTGGGAAGCTGACCCCAGCCCAGGAGGTTAACCAGATGACCACACCAATCGAGCTGACGGTCGACCAGGTGGTCGACCGCCTGGCCGCGCTGGACGGCTCCCTGCCGGCGGCCGACGGCGTCCGGGTCTTCAACGACATGTACCTCACCGTCACCAGGCTGGTCCGTGACCACCTGCCCGGCGCCTACTTCGCCGACCCGGCCGGGATGGCCCGGCTGGACGCGATCTTCGCCGCCCGCTTCCTGGCCGCCGTGGACGCCGTCGCCGCCGGGGCCGACCCGAGCCCCTGCTGGCGCCCGCTGTTCGAGCTGCGCTCGCACCCCGGCATCGAGCCCATCCAGTACGCGCTGGCGGGCATGAACGCCCACATCGAGTACGACCTCCCGGCCGCGGTGCTCGCCTACTGCCAGGCCGCCGGCCACACCCCGACCCAGGTCGAGGCCGACTACCACCGGATCAACGACCTGCTCGCCCAGGTCGAGGCCCAGGTCCGCCGACAACTCGAGCCCACCGCCCTCCGCCCGGCCGACCCCCTCCTCCACGTGATCGGCGTCTGGTCCGTCGACCGCGCCCGCGAGGCCGCCTGGGCCAGCGTCCTGAGCCTCTGGGAGCTCCGCCGCATCCCCCCGGCCGCCCGCGCCGTCCAGACCGCCCTCGCCCAGTCGGTCGGCATGGTCAGCCGCGCCCTCCTCACCCCGCTGGGCTGACCCCGCCGGCCCGGGACGCCGAACGGCCCGGCCGGGGAGTTCCCCGGCCGGGCCGTTCGGTACGAGCAGAGGCGTTACGCCCAGCTGGAGTGCAGCGGCTTGCCCTCGGCGTAGCCGGCCGCGCTCTGGATGCCCACGATGGCCTTCCGGTGGAAGTCCTCGAGGTTCTCCGCGCCCGCGTAGGTGCAGGAGCTGCGGACGCCCGCGATGACCGAGTCGATCAGGTCCTCGACGCCCGGGCGGGCCGGGTCGAGGAACATCCGGGAGTGCGAGATGCCCTCCTCGAAGAGGGCCTTGCGGGCCCGGTCGTAGGCCGACTCGGCGGAGGTCCGGTTGCTCACGGCCCGCTTGGAGGCCATGCCGAAGCTCTCCTTGTACTGGCGGCCGTCGGCGGTGGACTGCAGGTCGCCGGGCGACTCGTAGGTGCCGGCGAACCAGGAGCCGATCATCACGTTGGAGGCACCGGCGGCCAGCGCCATCGCCACGTCACGCGGGTGACGGACACCGCCGTCGGCCCAGACGTGCTTGCCGAGCTCGCGCGCGGCGGCGGCGCACTCCAGCACGGCGGAGAACTGCGGCCGGCCCACGCCGGTCATCATCCGGGTGGTGCACATGGCGCCGGGGCCCACCCCGACCTTGAGGATGTCGGCGCCCGCCTCGACCAGGTCGCGGACACCGGCGGCGGAGACCACGTTGCCGGCCACGATCGGGATCTGCGGGTCGAGCGAGCGCACCGCGCGCAGCGCGCTGATCATCGACTCCTGGTGGCCGTGCGCGGTGTCCACCACCAGCACGTCCGCCCCGGCCCCGATCAGCGCCGCGGCCTTGCCGGCCACGTCGCCGTTGATGCCGACGGTGGCGGCGATCCGGAGCCTGCCGTTGGCGTCCACGGCGGGGGTGTACAGGGTGGCGCGCAGCGCGTTCTTGCGGGTCAGGATGCCGACCAGCTTGCCGTGGGCGTCCACCACGGGGGCGAGCTTGCGGTGCGCCTCGTTCAGCTTGTCGAAGGCGACCCGCGGGTCGATGCCCTCCTCGAGCAGCAGCAGGTCGCGCGACATCACGTCGGCCAGGCTGGTGAACCGGTCCACGCCCTGGCAGTCGGAGTCGGTGACCACGCCGACCGGCTTGCCGGCCGCGTCGACCACCACGAGCGCGTTGTGCGCGCGCTTGGGCAGCAGGGAGAGGGCGTCGGCGACGGTGTCGCCGGGGGTGAGGGTCAGCGCGGTGTCGTGCACCAGGTGGCGCTGCTTCACCCAACCGATCACCTCGGTGATCACCTCGGTGGGGATGTCCTGCGGAATGGCCACCAGGCCACCGCGGCGGGCGACGGTCTCGGCCATCCGACGGCCGGCGATCGCGGTCATGTTGGCCACGACCAGCGGGATGGTGGTGCCCGTCCCGTCGTTCGACGACAGGTCCACGCCCTGCCGGGAGCCCACGGCGGAACGGCTGGGGACCATGAAGACGTCGTCGTACGTGAGGTCGTACGGTCCCGAATAACGGTCGTCAATAGTGCCGGTCTGAGGATTCAAGAAACGCATGAAGAAGGCTCTCTGACTTCGGGAGGGTAGACCTCGGGTGCAGTTAGGTCCGGCCGACCGAGCGCACTCGGGCGCCCCGCACCCAACCGTCAATGCTTGCCGATACCCAGGCCGAAAGCCAGTTCACACGCAATCCTTGAAGATCCATACAGAGATCACCAATCCGTACACAGGATGGCTTGTAGGAACATACAAGAACAACGCCTGAGGCATCTTTCGGCGCAGCTTGCAAGGAGGTCGACTGCCGACCCGGGACAGCCTCCGCCTCACGCAAGGTGCTCATCACGGTCGAGACGCAGGGCTAGGGGCACCGTGCCCGGCTGCAACGGCCCCACCCGCCGGCTGACCACGGGCAACTCGCCTCTGACACATACCGTCGGACACCAACCAGACGGAGAACGGCACCAAACCACCGAACCCCGGCGTCGCCAGAAGGCGAGGGCGGCGGCGCCCTGCACACCGACGAAGCCCCAGCGGCGAATCCAAGATCGCGCCCGGCCAGCCGACCGAATGCTCCTGGGCCCCCTGCGTGCACACACCTAGCAGGACAGGAAGCCCACCAAGATCTCCCATGCGCTGGAGCGTTCCTCGGGCGCTATCTCCAACGCGCTGACCACTTTGGCACCCTGGATGAGGCTGATGTGGACTGCGCCCAGCTCCGCCGCTGCCCAGAGGTCCAGCCCGGCTTCTCTCCCGACCGCCGAGCCCGGCAGCTGATGGACCCTGCGAGCCTCGGAAGGCAGCTCTCCATCGCGGGCATCCCCACTCTCGACGGCCGAACCGCGACTCTGCAGCAGTTGGCCCTTCAGGCGCCACCATCCGGCGTCGCTGAAATGCTCGGCTACCACACCGTCCACACCGGGGTCGTCGGCTGACAAGCCCGTGGAACCTGGAAGAAGTACGCTCGCGGCGACCAAACTCGCTGAAATTGACGACCCTCTCAATGAGTAAGACTTCGACGACTCTAAACGCTGAGTCAGTCCGAATCGACGGCCCCTATCACCTATTCGGACGATAGACGATCTCGACTCCTGGCCGATGACCATACGTTGGCCATGCGGGGCGATCCAGCACGGATAACGAGAGCTGAGTGTTCAAGCACAAGAAGACACACGATGAAGTGAAACTGCAGGCCAGTGCACAACTGATGACTTGGCACTGGTATTCCCAGGACCAAGTACTCGCAGCTGCGATGTTCTCTCGGAAATGCGGGGAAATGGAGGCTAACCGGGCCACCCCCACTGACGACGAGAAGCGCCGGGGACTCACCTGGGCTGAGGCGGAGCAGACGGAACACCGCTCCTACGTCGTGGCCTCGGTCCTCGCCTCGGTTGCCTTAGTGGAGGCGTCGCTCAACGAGCTCTTCGCCTCCGCACCTCACGAGAACCTGGAGGTCGGAGGGGGCCGCGGAGCCCTCTCAGCGGGTGAGCGGCGATCTCTCACCGACTTGACAGGGATGTTGGACCGGAACGACTTCTCGACGAGCAATAGTCAAGAGTTGTGGGTGGGGCCTTCCGGCGCGGCGATCTCGGCTGCCGCGAGCCGGGCGTCTTCACGCATCTGCGGGTCGAGGTGGTGGAGGAACGGCTCGATCAGCGGCAGGGCCCGTGGGTCGTGGGTGGCGCCGAGGATATAGAGGGCGTGTTCGAGGAGCTCGGGCTCCATCGTCGTCATGGCGGTCGCCAGCGGTTCGACGAGGTCCAGGGGCAGGCGGTGGTGGTTGAAGGCCTCGCTAATCGAGTTCAGGGCAGACTCACGGACCTTGGTCTCCGGTTCGTTGACGGCCAGGCTTACCAGGCGTCCGACGACCAGGTGGGCGGCGTCCGTGTCGAGTGCGGTGCCGCGCAGGAGATCCCCGAGGCTGTCGGCGGCGACATCCCGACGGTTCGGCTCGCGGTCGGTCAGTGCTTCAAGCGCCTTGATCATGTCGTTCATGCTGCCACCTCGGACCGCTCGGCCAGGACGCCGTTTTCGAAGCGTGCGCCGGCACGGACCAGGGACACCAGGTGGGCGCCGGTGATCGCGCGCCATCGGGCCTGGGCGGACTCGACCAGTTTGAACACCATCGCGAGCGCGGCCGTCGGGCTGCCGGCGCCGCGGGTGACCTTGGTGCGGAGCTTGACCGTGGAGAAGGTCGACTCGATGGGGTTGGTGGTGCGCAAGTGGATCCAGTGCTCGGCGGGGAAGGCGTAGAACGCGAGGAGTTCGTCCCGGTCGTCGGTGATCTTCGCGACGGCCTTGGGGAACTTGGCGCCGTAGGTCTTCGCGAACGCCTCGATGGCCTTCTCGGCATGGGCGCGGGACTCGGCGTTGTAGATCTCCTGCATCGCCTTCGTCGCCCCGGGCTGCGCGGACTTGGGCAGGCAGTTGGTGACGTTGCGGGGTTTGTGAACCCAGCACCTCTGCGGCCGTGCGGCCGGGAACACCTCGGCCAGTGCCCGCCAAAGGCCCATGGCGCCGTCGCCGACGACCAGCTCGGGGGCGCGCATGCCTCGGCGGCGGCAGTCGCGCAACAGGTCGGCCCAGGACTCGGTCGACTCCCGCAGGCCCTCGGCAATCGCGATCAGCTCCTTGGTGCCGTCCAGGCGGACGCCGAGCAGGACCAGGACGCACGAGTGGGCCTGGCCAAGCCGGACCTTCGGGTGCACGCCGTCAGCCCAGACGTAGACGAAATCGCGGTCGGACAGGTCCCGGTCCTGGAAGGCGGCGTGGTCCTCGCTCCACTGCTTTGTCAGCCGGGTGACGGTGGCCGGGGAGAGGCCGGCCGTACCGCCGAGGAACTGCTCCAGCGCCGGAACGAAGTCGCCGGATGACAGGCCATGCAGGTAGAGCAGCGGCAGCACCTCGGAGATCTTCGGGAACTTGCGGCACCACGGCGCCAGGATCTTCGAGGAGAACCGCTTGCGCTCGCCGGTCTCGTGGTCGACGCGCCGGTCGTTCACCCGCGGGGCCCTCACCTCGACCGGTCCGGCGGCGGTGACCACTGTCCGGGGCCGGTGGTGGCCGTTGCGGACCACCAGGCGGCGCCCGCGCCCGTCGGTCTCGGCCGCCAACTCGGCTATGTACTGGTTGACTTCCGCCTCCAGCGCGGCGGCCAGCATCCGCCGAGCTCCCTCCCGGACGATCTCGTCGATCAGGGAGCCGGACTGCGTGGAGCCGTCGTCGGTGACTACGCTGAGCACGGGCGTGCCTTCCCGACCCGCGCTGCAACGCGGGCCTACTCGGAGACCATCAAAGGATCATTCGGGAAGGTACGCCTTCCGCGTGCCTGTCGGCACTGATCCACAGGTCTCCAGCATTGCTCGGGCTTCGCGGGACGTGACGCTCGTGTACGCGGGAAACCAGTACGACCGCGACGACGCTTTCGACCGCTTCTTCGCGCCGGCTGCCGCCCACGTCGACCACCAGGTCGTCGGCAAGTGGACCGACACCGCCCGGTGGCCCCACGTCCGCTTCACCGGTCGCAAACCGTTCCCTGAAATCGCTCGCCTGCACGGCCGCGCCTTGGCCACGGTGCTGCTCCTGCCCGACCGATACGCGGCGGTCGGGCAGCTGACCCAGCGGCTGTTCGAGGCGGTTCTGGCCGGGTGCCTACCGCTGGCTCCCGACACCATCCGCGACGTCCACCGGTTCGTACCGCCGCAGCTCATCGTCCGCGACGGCACTCAGGTCACCCGCGTTCTCCGGGAGCTGCGTGAGCAGTCCGGCACGGCCCAGCACGCCCGTCTTCTCGCCGACTGTCTGGAGCGTCTCAACCTGTTCCGGCTCAGCGCCCAGATCGAGCGGCTGGAGCTGGCGATCGACGCCGCTGCCGGGGCCACGCGGAACAGGTCGGTGGCCTGATGCGCATTTCCCTCCTGCCCGCTGCGGCACCCATGGCATCCAGAAGTCGGCCTGCGCATTCCGGGCTCCCCGCTCCCTCTACTGTGGAGAACCATGAAGAAGGTCGCCGTCGTCGGCTGCTCCGGCAGCGGCAAGTCGCATGTCGCCCGGGCGTTGGGCGGCATCCTGGACGCGCCGGTGACACACCTGGATGCCGTCTTCTACGACGAGGACTGGAACGAGCTGCCGAAGAACACGTTCGCCCAGGCTCAGCGGGACCTGGTGGCCCAGCCGCGCTGGGTGATCGACGGGAACTACAACTCCACTCTGCCGATCCGGCTGGAAGCCTGCGACACCGTGGTCTTCGTGGACGTGTCCACCCTCGCCTGTCTGTGGGGCCTGCTCTCCCGGCAGCTCCGGCACGGCAGCGGCCAGAAGGGCAACGGCGTTCACAACCGAGTCCATTGGGGACTGCTCAGGTACGTGGCCGGCTACCGGCGCACGATGCGCCCGCGCGTGCTCGCCAAGATCGACGAGTACGCCGTCCACGCCGAGGTCGTCCGCCTTTCCAGTCGGCGCCGCACCCGCCGATGGCTGCGCGAGGTGCAGCGAAGCACCTGAAGACCCACCCGGGACCGAGCGGCTCGGCGCCTGACGGTCGGCGGGGAGGCGCGGAGTGATCGTCTCCCCGCGTCACCACACCAAGCACTACTCCGACCCGGCCCGGTGCGCTGCGGCGCGCCGCCACTACGCCTGGCTCGCCGAGTACGCTCCCACCCTGCGCCAACCGCCACTGATCGCCGCTACCCCGACCAGTCTGAGTGGCTGTTGTCTTTCCTGACTTGAGAGCTGTGTTTCCGCTGGTCAGGCATAGGGGCGGTGGTCTCGGGGAGTGGTGACGTGTCGTGTCGTCGCTCTGGTGGAGGTCAAGGATGCCGTCGGTCGTGGGGCTGCTGGAACAGCGTGAGCTGACCGCTCGCCGTCGTGTGGATGAGCTGCGGGAGGAGGCGGACCGTATCCAGGCCGAGCTGGTCGCGGCCGAGCGGGAGTGGAGCGAGTGGGTCATCGCCCGTTCACGCGTCGGCGAGGTGCTGTCCCCGGGCGAAGGAGACATCGCCGGCCCGGACGCCGTCGAGAAGCCGTCGGATCGCGGTGAACCGCCGGCGCTGCCTGCATCTTCGGCAGCGGCGAAGCCGAAGTCGGTGGTGCCGATGTGGCGTGCGGGTCTGGCCCGGTCGGCACTGTCGGCGGACTACCAGCGCATCGTGCAGGCTCTCGCGGACCGAGGCCGTCTCGGTCAAGGCCCGCTGACCTGCCAGGAGATGGCCGCCTGCTTCGGCCTGGACCCGGTGCCCGCGAAGATCGAGGCGTTGCGGTCGAAGGCGAAGCGGCTGACAGCGCGCGGGTGGCTGGTCGAGCCGGAGCCGGGCCGGTTCACGCTCGCGATGGCCTTGGCCGGGCCAGGCGGCGGGTCATGAGCATCGTCGCCGACCAGTAGACCATCGCCTCCGCGCTGCCGGTGGACCGTTCGAAGTCCCGCACGAGGCGGCGGCTTCGCATCAGGTGGGCGAAGAACCGCTCCACGATCCACCGCTTGGGCAGCACGACGAAGCCGCGCATGTCGTCACTGCGTTTGACGATGGCCAGGACCAGGGCGAGGACGGTGAAGCCGTACTCGACGAGGCTGCCCGTGTAGCCGCCGTCGGCCCAGACCAGCGCCAGCCGGTGGTGTGCGGCGGCCACCTGGGCGAGCAGAACCTGCGCGGCGGCGCGGTCGCCGATGTCCGCTGCGGTGACCATCACCGCGAGGAGCAGGCCGAGGGTGTCGACCACGGCGTGCCGCTTGCGGCCATTGATCAGCTTGCCGCCGTCGAAGCCGCGGCTGTCACGGCCGACGACGGCGTCCGCCTTGACCGACTGGGAGTCGATCACGCCCGCGCTCGGCTCCGGGTCCCGCCCGGCCTGCTCGCGGGCCTTACGGCGGAGCCGGTCGTGCAACTCCCGGACCAGACCGTGGTCACGCCAGCGCCGGAAGAACGCGTAGACCCGGTCCCACGGCGGGAAGTCAGCCGGCATGGCCCGCCACTTCGTTCCGTTGTCGACGAGGTAGCGGATCGCGTCCAGTATCGTGCGGTGGCAGTACGCCTCCGGCTGCCCGCCCCGCCCGCGCAGCCAGCCCGGCACCGGCAGCAGCGGCCGCACCACCGCCCACTCCGCATCGGACATGTCGGTGGGGTAGCGGCGCACACGGACCCCGTGGTCGACGGCGTTCCCGAACCGGTGTGCCAGGCAGTCACACGCGAGAGTGACCGAAGTGGACCCCGGTCCCGCGATGCCGTAGAAGTGGGACAACAGGGCCTCCTGGACCGCTCTTTGGCGTAGACACCCTTCGAGCTACCAAGAGGCCCTGCTTTCATGCGCGGCGGCCGCTGCGCTCACCCGATCGAGACCCCCGTTCGACCCGCGCCCCTCAAGATCGAAACGACAACAGCCACTGACGTTCGGCCGTATCGAGGGACGGCACGGCGAACCGCGTGACCTGCTCCCGCTGGCCACCATGCTCGGCGACGCCCATGGGACCGCCTGGACGTACGACTTGCGCGGCGCCCGCCTCGACCGACCACGTGCGCTCGCCGACGGCGCCGGCCTCCCCGACTACGTCTCCCCGCGCCGCCGAGCGTTGGAGCGTCGCCTCCTCCAGGGCTTCATTTCGGACCGTGAAGCGCTCGACCTTCTTCTCGGTGTTCTCGGGCGCACTGCCGACGGCCCGGCCGCGTTCTACAAGGACGCCAACCCGCGCAACGTCCTGATCACCGCGAGCACCGTGTACACCGTGGACGTCGACGACCTCACCCTGGCACCCTTCGGCTACGACCTCGCCAAGCTCATCCATACCCTCGCTCTGAGCCACGGCCCCCTGCCGCCGCAGGCCGTCCGCGACGCCGTACAGCACTACAACACCGCCGCAGGTCGCCACCACCGGCAACTCGGCTACCTCACCACCACCCAGCTGGACGACTTCCTCCTCCTGCACCGCGCCCTGACCGCCCCGTACACCGACCGCGACCACTACCGCAACGGCCGTCCCCAGCCCCTCACCCAGGAGGCGCAGTGATCACCAGCGAAATCGTGCTCCTGCGGCACGGCCAGGCCCACTGCAACGCTGCCGGCCTGGTCGGCGGCCCGGCCACCTGCACCGGCCTGACCGACCTCGGCCGCCACCAGGTCGAACAGGCCGCCGAACTCCTCGCCGCCGAACACGCCGCTTCGCCGTTCACCGCCCTGTACGCCGGTCCCCGGCTCCGCCTCCAGCAGACCGGGCAGATCCTCGCCCTCGCCATGGGCCTCCAGCTGCTCACCGACCCCGGCTTCGACGGCCCCGAGCACGGCGACGCCGACGGCCGACCCTGGCGCGAGGTCAAGGACTCATTCGGCGGCGCGCCACACACCCGCCCCGATACCCCGTGGGCCCGAGGCTCCGACACCTGGAACGGCTACCTTCAGCGGGCCGGAGCCCACCTGCGCAAACTCCTGACCCGCCATCAGACTGGTCGGCTCCTCCTCGCCGCGCACGGAGAGACCGTCATAGCAGCCCACGTTCTGCTCCTCGGCCTCCCACTGGGCTCCGTCAACGGATTCTCCGTGGACCACGCCTCACTCACCCGCTGGCAGCATCACCGCAACCAGCGTGGCCAACAGCGCTGGCTCCTGCACAGCCACAACAACACCGCCCACCTGGCTCCTCCACCGGAGCAGCCGTGATCACCCGCACTGACGACCCGCGTCTGGTCCTCGCCCGCAGGAGCGTCGGCCCGGTCACCATCATCGCCGAACCCGGTCTACCCGACCGCGTCCTCCACCTGGCCGACAGCCGAGGCACCCGCTACTTCGCCAAGCAGCACCACCAACCAGCCCGCTTCACTCAGGAGGTCAACGCCTACGCGGGCTGGGCCCGTCATCTCGCCGCACGAACACCCGATCTGGTTGCCCAGCACCATGCCGACCTGGTCCTGCTCATCACCGCCGTTCCCGGCCGCCGCGCCAACACCCTGCCACCAGGCTCGGACGCCGAACAGCTCGCCCACCGCGCTGCCGGAGCCGCCCTGCGCGCGCTCCACACCGCTACCGCCATCACTGACCCAGACCTGTGCAGCAAGATCAGCAGCCGTCTTCGCACCTGGATCGCCAAGGCACACCAGGCAGAACTCCTATCCGCTCGGGAGCACCAGACCCTGAGCGAGGCTGCCGACCAACTCACCCACCAGCGCATGGAAGCCGCCGTCTGCCACCTCGACTACCAGCCCCGGAACTGGTGCGTCGGTAAAACCCTCGCCGTTGTCGACTTCGAGCACAGCCGCCCTGACGCCCGCATCCGCGACCTGGCCCGGCTCGCCTTCCGGCACTGGCCTCGTTCCCCGCACCTGCGCCAGGCCTTCCTCAGCGGCTACGGATGCCTCACCAGCGTGGAGGAGAACCTCCTCCACCTCTTCGCCGCTTACGAGGCCGTCACCGCCCTGGTCCGCGGCCACGAAAACGCCGACCGCGACCTCTCCGCCCACGGACGCGCCACCCTCGCCCGCCTCCTGCCTTAACTACTCCCGCCACCTCGGAGCCCCGCCATGTCCCAAGCCCAACCCCATGCCCCGCAGCGCGCCGTCATCACCGGTGCGGCCGGATTCATCGGCTCCCACCTCGCAGAAGCGCTCCTGGCCGCCGGCACGACCGTCATCGGCGTCGACCGTCGCGACCACAACGACCCGCGCGCCGCGGCCAACCTGGCCCGGATCCTCGACCACCCCGCCTACATCCACGTCACCGCCGACCTTCTCACCTGCGCGGTCGAACCCCTGCTCCTCGACGCCGACGCGGTCTTCCACCTCGCTGGCATCCCCGGCGTCCGACCCTCCTGAGGACCGGAGTTCAGCGACTACGTCAGCTCCAACATCCTGGCCACCCAGCGCGTCATGACCGCCGCCACGACCATGCGCGTCCCCCGCCTCGTGGTCGCCTCCTCCTCCAGCGTCTACGGCCCCACCGACGGCACCCCCAGCGCCGAGAACGACCCCACCCGCCCGGCGTCCCCCTACGCGGTCACCAAACTCGCCGAGGAACAACTCTGCCTCGCCCACGCCACCCGGCCGGGCTCCCCCACCACCGTCGTCGCCCTGCGCTACTTCACCGTCTACGGGCCACGCCAGCGCCCCGACATGTTCATCCACCGCGCGCTGAACGCCGCCCTCGCCCGCACCCCGCTCCGGCTCTACGGAGACGGCCACCAGCAGCGCGACTTCACGTACATCGACGACGTCGTCACCGCCACCATCGCCGCCGCCTCCCCTCAGGCCCCCGGCGGAGTCGTCAACGTCGGCGGCGGTACCAGCGCGACGCTGCGCGACATCATCCGCTCTGCTCAGGAACTGTCCGGCCGACCCATCGAGATCCAGGCCCACACCACCCGCAATGGCGACGTCCCAGTCACCCGGGCCGACCTCGCCCGTGCGCGCCGGCTCCTCGGATACAAGCCGACCGTTGACCTTTCGACCGGCATGAGCCACCAACTCGCAGCCCTCACCCACGTCACTGCTGCCATCTCATCCTGATCCGCCATCCGAGGCGTCGCCTCGGCCCCGCTGCTCTCACTCGCCCCAGCACCAAGCCACGGAGAACCGATGCCGTCCACGGAGACACAGCTGCCCACGCCCAACACCAACCGCCACATCGCCGTCATCCCCTGTCGTTGGGGAGCAAGCCGCTTCCCCGGCAAACCGATCGCCGACCTGGCCGGAAAGCCGCTCCTCTGGCACGTCTACCAGCGCTGTCTGCAGGCCACCACCATCACGCACACGGTCGTCGCGACCGACGATCAGCGAATCACCACCGTATGCGAGGACCACGGCATCCCCTGGATCATGACCGGCATCCACCCCACCGGCACCGACCGCGTCGCCGAGTGCGCCGAACGCCTCGACGCCGACGCTTACATCAACGTCCAAGGCGACGAGCCGTTCATCGAGCCCGCCGCCATCGACTCCGTCTCCACCGCGCTGGCCAGCCTTCCCCCGGGAGTCCTCGCGGTCAAGGCGTGCTCACGGCTCACCGACCCGGCCACAGTCCAGGACCACAACGTCGTCAAGGTCGTCACCGGCAACGACCACCGCGCCCTGATGTTCTCCCGCCTGCCCATCCCCTACCCGAAGAGCGATCGACCGACCTACCTACGCCAACTCGGTCTGTACGGCTTCACACCAGCCGGGCTCGGCATCTTCCGGGCCCTACCTCAAGGCTCGCTCGAACGCGCCGAGGGTGTCGAGATGCTGCGATTCCTCGAACACTCCCACCCGGTCCAGATGGTGCTCACTCACGACTCGGGCACGGCCGTCGACACGCCAGAAGATCTCGAACGGGCCGAGGCCCAACTGCTCAGTCAGCGGTAGATCTCGATCGCGGTCTGACCCGCCCTCACGACTCACAAGCGACTCCCAAAGCGGACGTAGCTTCAGGCTTTCGCTGTTCGGGCATGTAGTCGCCGCAAGACCCACCTTGGGTTCTAGGAGTCGTTGCAACACCCCAGTTCAGGGGATGCGATGGACTTCGAGATCCGTGGCAACCGCAGACCGCAGGGTCGGCGGAAGCTGCTGCGGGAGCGGGCGGCATACTCCCGGCTCGTGCAGCAGGGCGTGAGCAACACCGAGGCATGCCGGATCGTCGGCGTCGACCGCAGGACCGGCCAGAAGTGGCGTAACGGGCGCAAGCCGACCGGCACCCAGCGCACGGCGCCGGCTCCCCTCGACCTCGACGGGAAGCCGGCGCCGCCGACCGGGCCGGCAGGGCGGTCACGGTTCCTGACCGAGGCGGAACGGATCCACATCGCCGACCGGCTGCGGGAGAAGGCCACCGTCCGGGCAATCGCCGCGGAACTCGGCCGCAGCCCGTCCACCGTCAGCCGGGAGATCACCCGCAACGCCCACCCGGTCAGCGGCGCCTACCGCCCGCACGCGGCCCAGGCCCGCGCGAACGCCCGCCGGCCCCGCCCCAAACCGCGCAAGATCGGGCAGACTCCCGAGCTGCGGGACTTCATCCAGCACCTCCTGGACCTGAGGTGGAGCCCGGAGCAGATCTGCCAGGCTCTACGGGAAACCTTCCCCGACCGGCCGGAGATGCACGTGGCTGTCGAAACCGTCTACCAGACCCTCTACCTCCAGGGCCGGGGCGAGTTGCGCCGCGAGGTCGCCGCCGCCCTGCGCACCGGCCGGGCCCGGCGGATCCCGCACCGGCAGGCCGCCACCCGCCGCCCCCGCTTCGCCCACCCCATGGTCATGATCAGCGAACGCCCCGCGGAGGCGGACGACCGGGCCGTCCCCGGCCACTGGGAGGGCGACCTGATCATCGGCAAGGACGGCGCCTCGGCGATCGGCACCCTGGTCGAGCGCGCCACCCGCTACGTCATGCTCCTGCACCTCCCGGCCGGCCGCGGCGCCGAACAGGTCCGCGACGCCCTCGTGGCGACCGTCCAGACCCTGCCCGCCCACCTCAGGCGGTCCCTGGCCTGGGACCAGGGCGCCGAGATGGCCCGGCACGCCGACTTCACGATCGCCACCGACGTCCCGGTCTACTTCTGCGACCCCGCCAGCCCCTGGCAGCGCGGCTCCAACGAGAACACCAACGGCCTGCTCCGCCAGTACTTCCCCAAGGGCACCGACCTGTCCGTCCACAGCCCCGAACACCTGGCCGCCGTCGCCGCCCAACTCAACGGCCGCCCACGCAAAACGCTCGACTGGGACACCCCAGCCGAGCGCCTGCATAAACTCCACACGGCCTAGACAACCAACCACGTGTTGCAACGACCGCTAGAAACCACCCACCGACCCGGGCACGGTGGCCGGGACACCCGTCCGCGGTAACGACGCAGGCCCGGCCTCGAGAGACCGCGAAGCGTCGCGAACACGGAGCCGCTCGCGGCCAATCCGGAAGCTCGGGCGGAGGTCGCTGGGCCGGACGACGGCGACCTGCTCATCGGATGCCCCCGGTACGAACCGGGTCAGGGGAGTGGCAACGGTACGGCCGTAGAAGAGGCACCCGATCGGCGGCAGTTCGCCAGGCCGAGCAGCACTCTGGCGCTTGCGGCCGAGGTCAACCGTGGCGGCCAACAATTGCCGGTCTCTCTGCCTGGCCCTATCGCCGATGCTCCGTCACTCTTGGCCGAGTACGTGTACATGCGGACCTGTGCGGCGTTCCCAGTCGCATCGGCGGAGAAGTGAAGTGGGGGCGGGAATGAGGTACCTGATCGAATTACCGGTCGGTAGCAGCATCGGATCGCAGGAGTCGGTGCGAGTGGAGGTCGAGTCGCCGGACGACGGGCTGGTGCCGGTCTCCCGGCCCGGCCAGGTGGCCGCACGCGCCGCACGGTCGCTGGGCGAGATGCTGACCGGAATCCGGCCGGTCGCGGAGGCCTTCGTCGAGGGCCTGGGGGGGAATGGCCCACACACCGGACGAGGTGTCCCTCGAATTCGGGCTCTCGATGTCCGCCGAGGCCGACCTCGTGATCTCCAGCACCACCGCGCAAGCCCACTTCAAGGTCTCCCTGACCTGGCATCCCCACCCTGCGGCGGAGGCCGCGGAGTGACCGGGGTCGACGCGGCCGCCTTAGCCGTCCCGGAGGCTCTGGAAGCTGCCCTGGTGCGAATCTACGGCCAGTCCGGTGCTCCGGTCGGCGTGGGCTTCCTGATCTCCGACCGGCTGGTCCTGACCTGCGCGCACGTGGTCAGCACCGCCCTTGGCCTACCGATCGCGCAGGTCCCGCCGCCGGACGCCTGGCTCGCCCTGGACGCGCCGATGGCCGGGGGCCCGGAGTCGCCCGAGCGCGAGCGGGGGAGCGTCCGAGTGTGGGGACCGGCCCAGCCCGTCGGCGCCGACCTGGCCGTCCTAGACCTGGAGCATGCACCGGTCGGTACCCGGCCGGCCTGGCTGGTGGACACCCAGGGGCAGCAGCTATGGGGTCACGAGGCGCGGGTCTTCGGGCTTCCGCAAGGCCGGTCCGCGGGGGTGTGGCACCAAGGCGTTCTACGGGCCCGGCAGGCTGACGGCTGGACCCAGATCGATCTTGCCGGGGAGGGCTACCGGGTTTCGCCGGGCTTCAGCGGCAGCGCCGTCTGGGATCAGGAGCTGGGCGGCGTGGTGGGCTTGATGGCCGCGGCCGAGACGGGGAATCCCCCGGTCAGCTACATGCTGCCCGCTTCACTGCTGTTCTCCTGCTGGCCGGAGCTGCGCTCGCATTCCCTGCCGCCGTCGCCGTTTCGCGGGCTTTCCCCGTTTCTGGAAGGTGACGCGGGGTTGTTCTTCGGCCGGGACGGCGACGCAGACACACTGGCGTCGGTCACGGTTGCCGAACGCTGGACGACTGTGGTCGGACCGTCCGGCTGCGGCAAGTCGTCGCTGGCGATGGCGGGGGTGGGCCCGCGTCGGCGCCGGGCCGGTGATTGCACCGTCGTCGTCCGTTTCGCCTGGTACGACTCGCCTCTGCGCGCACTGGCCGCTGCACTGCTGCCGCTGCTGGGAGCCGAACCCGGCGACGAAGCAGAACGGTTCGACCGGATCACCGACCTCGCTGCGCACCTCGGCGCTCACGGGGTCCGCGAGAGTGTCTTCCGGATCCTGGAACGGCATGGGGCCTCCAGACTGCTGGTGATCGTCGACCAATTGGAGGAGCTCCTCACCCACGACGACGACGGCATCGGGCAGCTCGCCGAGGTGCTGTGCGGACCGGCCACTCCGGCCGAGCTCGCGGTACTGGCCACCCTGCGCGCCGACCTGCTCGACACCGCCCTCACCCATCCCGTGCTAGGGCCGGTTGTCAGCCGCCGCGTCCACGCGCTCGAACCGATGCGCCCCGAGCAGCTGAGCGAGGTTGTCTCCAGACCGGTCGACACCGTACCCGGCGTGTTCTACGAGGAAGCCCTCGCTGAGCGCATCCTGGCCGATGCCGGCGCTGATCCCGGTGTCCTGCCGCTGCTCGGCTTCACCCTCGACCTTCTGTGGCGCCGACGAGACGGCTGGCTGATCACCCACCAGAAGTACGCCCGGCTCGGCGGAGTGGCCGGCGCCCTCGGTCGCTATGCGGATGAAGTCTGGGAAGCCGTGGTGCCCGCTAGGGAGGCCGACGTGGCCGAGCGGTTGCTGACCCGCCTCGTGCGGATGCCGCTCGGCGCGGCAGCTCCCGTGCGCAGGGCCGTCCACCGCTCCGAGGTCGACGCTGCGGAGTGGGCCGTCGCCGAACGCCTTGCCCAGCGGAGGCTCCTGGTGATCCAGGGGCGGGGAGGTACCGAGACCGCCGAGCTGGCTCACGAAGCGCTGATCACCGCCTGGGCCCGGACGCGGGACCTGACCACCGCCGACCGCGCTTTCCTGGCCTGGCGTGAGAGTGCGCAGACCGACCTCGACCGCTGGGAGCACGCGAAGCGCCCGGCCGATCTGCTGCCGACCCGTACAGCCCTCGCCGCCGCCCGTCAGTGGCTCCCCGCCCGCTCGGGCGAACTGAGCGCGGCGCTGCGCGACTTCCTCGACCGTGGCAGGCGACGCAACCGCCGCCGACGCGGCACGCTCACCAGTGTGGTAGCCGCCGTGTGCGCCCTCCTGCTGGCCGCTGCCGCCCTCGGGGTGAGTGCCCAGCGCAATCACCGCGACGCCGCGCATAACGCCGCGATCAACCGGGCAAACACCCTGGCCACCGACGCGGCGGCTCTCGCCTCCTCCGACCCCGGCTTGGCCGCCCAACTCGCGGTCGCGGCGTTTCGCTCCGCGCCCACACAGGCCGCCGTCGACCAGCTCTACGCCTCCATAGCCGGACCGCTTGACCAGGTGCTGGCCAGCACCGGCAGCCCTGTCGTGCAAGTGGTTGCACAGGCGCACGGTCCGCTGGTCGCGGCCTCTAGCGAGAGCGGTTCGGTCCGGGTCTGGGACACAGGCCACCTCGACACCCCCCACCTCGTGTCAACACTGCCTTCCACGAAGGGAGGGGCGATCGCCCTGGCACCGCGCGCTCCTCAGCTCGCGGCCTTGTGCCCGGACCAGGACGGTCTGTGCCTGATCTCCCTCAGTGATCCGCAGCACCCGGCCCGGCTCGGCCAACTGCCTACACCCCACCCGTGGCCCAGCGGCGAACTGACACTCACCTCGCTGGCCTTCAACCCGGACGGAACGCTACTGGCCGGCGCCACCGACGCCGGTTCCAGCCTGCTCTGGTCGACGACCGACCCGACACACCCCAGCCTGCTGTCCACCCTGCCCGGCAAGGGCTCCGGCAAGAAGATCGGGGCCGTGGCCTTCTCTCCCGACGGCCGCACCCTGGCCGCCACCAACCAAGACGGCACCACCCAGCTGTGGAACCTCACCACCCCCGCCAAGCCCGCCCCCGCGGCCGCGATCCCGACCGGATACCAGTCACTGGCCTTCAGCCCGGACGGTGCCTGGCTGGCCGGCGCAGGCGACCTGCGGCTGGACCTCTGGAAGACCAGCGACCCGTCCACACCCATCGAGGCGGACCCTCTGCGCACGGTAGGCGATCTGATGAGCGTGAGCTTCAGTCCCAACGGCGGCCGCATCGCTTGGGGAGGCACGGGCATCAACGACTCGAACAGCGCGATGTGCCTGACCAGCGTCCAGTACATCAGCCCGGATAAGAGCTCCCGTTCTGCGCCAAGACCAGCTTCGACAGCCACACCCTCGCGTACACCTCCGGCGGTGCGATCCTCACCGGCGGAACCGACGGAACCGTACGCCTCTGGCGTGACCCCACGCCCCAGGCGGAGGGCATGTCAATATTTGACAGCCGCGACCAGTGGGACATCGGCCCCGACGGCCACCTGGTGGCAGCCCAGATGTCCATGAAACTACATCCCGGCAGCCCAAGCCGGGTGGGACTCTGGACCATCGACGACACCGCCGGTGCGCGGCCCGTAGGCACGATCGATCTCCCGGACACGCTGCAGCAGGTTACGTTCGTCAACGCGATCACCCTGCTGACCGTCGACCACAGCGGCCGCCCACAGCTGTGGAACATCAGCGATCCGAGCCATCCGATAGCCGGCACCGCGCTCACCACAGCCGATTTCACCACCTACCCCACCGGCTTGGGCGACTTCATCATTTCCACAGCGGTCACCGTCGACAAGGACCTGGCCACCGTGCAGGGCGGTGGGAAGCTCCAACTCTGGCGAGTGAACGGGAGCAGCGCCACCGAAGCCGGTTCACTCCCCGCCCCAGACCCGGCAGACGTGGCCGGCCTGCTCAACAACCATCAGGCCGTCGTCGCCGCCAAGGACGGCTTCACGTGGTGGGATGTCACCGACCCGGACCACCCGGTCCATGTGGCCGACACCCCTCTGGGAGGCGGCAACAAGGGCAACGTCCACGGCTCTGGCAGCGTGGTCGCCGCTGTCCTCGGCTTTCCCGCCGTGAAGAACACGCTCTTTCTCCTCAAATTCCCTGACAGCAAATCAGGTACCGCGGTTCAGCTCACCGACAATGCCGGCGGTGAGGTCGCGCTCAGCGACGACCAGCACTTTCTCGCCTCGGACGGCTCCGGCGCGAACACTGTAAATCTCTGGGACGTCCGCGATCCGGCCCATCCCCGGGCAACGGCAGCTGTCACCACCAAGCCCGGTGTCCAGGGCATGGCCTTCAACGCGGGCGACACACTCATGGCGACGTGGAGTGCGGCGGGCGTTCAACTGTGGAGCCTCCGCGACTCTTCGTCGCCCGCCTTGATCGTGAGCATCCCCACGTCGTACTCAGGAACGCCCATCACCACGTTCACGCCGAACTCGGCTTGGCTCGCCGTCGACACCTCCTCATCCATCAGATTCATCGACACCAACCCAAACGCACTGGCCACCCGACTCTGCTCCTACACGGGCAAGGCAATGACCCCCCAACAATGGGCACACGCAACCCAGGGGCTTCCCTACCAACCCGTATGTAATGCGTAGCTCAGTGGTCATGACCTCTGGGGCCCGTGGTCGGGCGGTCTACCCGCGAGCCCGGCAGGCAGACCCCATCAAGCCGCGCCTCAGCGCAACGACGGCCGCGGCCTGGGCTTCTGCCGTCCTCGCTCCGCCCTTTCTGGCTCCTGGAATCCGGTGACAAGCTCGTCGACCGTGACGGACGCGCGTGAAGGTTCGACGCCCCTTGGTGCTGGACCCCGTTCGACGGCGGCCAGCCGAGCACTCCGTCCTGGCCGCCTGCCCGGCTCCCACAACGGTGAGCCGACGCCTGAGAAAGTGTTGGGTAAGCGGGTGGCTACTCGTTCTTGAGGTCGTCGGCGAGGCGGCGGGCTGCTTCGGTCTCGATGGGGCCGCGTGGTTCGACCTCCTCGCCGGCGAGGCGGGCGGCCATCAGGCGGATCATGGCGACCTTGATCATCGCTTCGGCGTGCGCGGTCTTGCGCTCGTAGTCCCGTGCCAACCGTCTGCACCGCCCCAGCCAGGAGAATGTCCGCTCGACCACCCACCTGCGGGGCAGCACCTGGAAGCCTTTCACATCCGCGTTGCGCGGCACCGCCACCACCGTCAGGTCCTCGTGCGCGGCAGCCCAGCCGACCAGACCGGCATCGATCGCGTTGACGTAGCCGCCGTCGACCCAGACCAGCCCGACCCGCGGGAACAGACCACGGATGCCGGCCAGGACCAGCTTCGCGCCCGCCCGCTCCTGGACGGACGCGGAGTGCACGACCGCCTTCAGGACCAGTCCACAGCTGTCCACCAGCAGGTGCCGCTTGCGGCCCCGGACACGCTTGCCCGCGTCGTAGCCGATCGCCTCGCCGCCCTGGTGACTGCGTACGGACTGGGAGTCCGGCACCGCCGCCGACGGCTGCGGATCCCGACCGTCCGCGACCCTCACCCGGTCACGCAACACGTCGTGGACCCGGTCCCACGTCCCGTCGGCGCTCCACGCACGAAACCACCGGTAGGCCGCGTCCCACGGCGCCAGGTCGTGCGGCACCAGCCGCCAGGCACAACCACTGACCAGGACGTACAGAACCGTGTCGACGACCAGGCGGCGAGGGAACTTCAGCGGCCGGCCGCCCCTGCGCGGATCCCGCCCCGGCAGCAGCGGCTCGATCATCGCCCACTGAGCATCCGTCAACGACGAGTCGTACGAAGGCTTGCACGAACAGACACACATACCGGTGATCCTCGCGGGCTCCTCGACCACGAAGATCACCGGCCGCACATCACACCAAGCAGTCGATCAATTACCCAACACTTTCTGAGGCTGTCGCGGGGGCGACAGCCTCAGGCGGCCACCCCGACGAAGTGAACCGGTGGGTGGGAGTCACCCGCCCGGAGCGGATCACAGCCGCCTGACCTGCCTCGGACGTCGGCACCGCGTGTACCTGGTGTCGGTCAGCGTCCCCATGGGGACTCGTGACCACGAGGGTGGGGAATTGCGCCGAAACGAAACCGCAGTTTGTGGGGAATTGCGTGACCGCCGACGCGCTGTCCACCGCACCTCCGTGGACTATCGCGATCGACCCCACCCGGTCACCGGCTGCGACCGGTACTGCAACCCGAACCGGCCCTTCTGCCGATCAACCGAGCAAGATCTCTTCCGGTCTCCGGTTGAGAACTTCGAGTGGACGGCTGTTAAGCAGGTGCTCGACGCAACCGGAGAGATCGCCCCCGTGATCCTCCAGCGCGATCTCGCGGAGTTCCTTCACCAGGTCCTGCCCGTTGATGAGGACCACGGGGTACTGGTCCTCCACCATCTCGAGCTGAGCCGGTTCCGAGTACGAACCGGTGGTCACGTACACCCCGATCCACCCGCGACGGAGTCTGGCGACGACCCTGGCGATCTGCTCGGCGGAGACCAGACTGTCGGGCTTGATGCACTTCGCCTGCCCGAGGACGACGAGCTTCGTGCCGGCCAGCCCGCTGCCCAGGTCCAGCCGGCCTACGAAGTCCGCCCCACCGTCGCCCGACCGTCGGGTGAGCCACCCCTCGGTGTAGCTGTGTCCGGACGCGCGCATCACCCGGGCTGCAACCGCGGACGCCAGGGCCTCGAACGCGTGCTTGTCCCCGTCGAAGCGCCGATACACCGCCTCGAGATCCGTCTCCGCCGTGCTGCCGCTCGCCGGGCGCTGGTCCCGCACCTTGATCACCCTGCTTCGGGCCACCCGGCGGCGCACCCGCGGTAGCACCGAGTGTCCGCGCTTGACCCACTCCCGCCACGCAGTGGGGGCCAGCTCCAGCACCTCGGCGTCGGACCGACTGGCCACGCGTCGGGCCGTGATCCACTCCCAGTCCAGCTTGTCACCCTCTGCGGCGAGATCGATCACCGCAAGGTCGAAGACGTAGTTGGTGAAGGTGGTGCGGGCCCTTCCCGCCCACTGGACCACCCGCTCCGCCCGCTCGATCAGACCGACACCGCAGAACTCGACGTGGCCCTTGACCTTCCCGTTCCGTGACACCGAGCGGAACAGCAGGAGCGGTGCCGCGGCGGCCCGGCCCGCGGCCGTCGGAGCCTGATGTCCGTCGAACACCTCGAGCAGGGCCGCATTGCCGGTGGTACTTCCGAGCGGCTTCGCAGTGTCGAACTTGTGGTCGCCGAAGTAGCGCACATGCCCGTTGTCGAGATCGAACACGTCGTGCCACGGAGTCTGCTCCGAACCGGCCTTCCATGGACTGGACCTGATCATCACGGCGGGCCGCCGCACCCCGGCCGCGGCCGTGATCTTCGCCATCGGATTGATCCCGGCTTCGAGCAACGCACGCTTCTAGCCTGGACTGTCCGTCACAAAGTAGAAGTTGCTGAAGCCGTCGACGGTGGCCGGCCCGCTGTCCTTCGCACTCGTGTACCGAAGCGTCTCGCCCATACCCAGCACGCGCCCCACGGTTCCCCCTCCAGCAAGCGATCACGGACTATGCCGATCCTGCCACCCGGGTCCGAAAGGTCGCCGCTTCACCGGCAGCGTCCGTAGCCTGCGGGCGGGCAGGCGCATCGAGTGTTCGAGCGGATGAGCCGCGCGCCAGAACGACGATCGACCCTCAGTAGTCGAACTGGAGCTTGAGTGCGGACTCCAGATCCTCGCGCTTGATCCCGAGTGCGGCGGCAAGGACGTGCATACCGAGCCTCGGCGGTACCGCGTTGCCGATCTGCTGAGCGATGACGCTACGCACGCCCGGGGCGTCGACGCCCTCGACATCGTCGCCGTTCCGACGTCGCCACGGATAGTCCCGGCTGAAGGTCTGGAGCATCCCGAGCTCGGGCAGAGAGAAGGTTCCGAGGTGCTGCTCTCCCCAAACCAGCTTGTTACGAGAAGCCTTGCCGGTCACGGTCGCCGACGGCTCGTCGTGCCGTCGTCGCCCCCGCGCCCTGGGGTCGCCCCCCGTGCCGTAGTTCGACACCACCTCGAAACAGTCCGTGCGCCCCAGGGCCTCCTGCATGGTCGCCCAGGGAAGGCGGGACGAATCCCCCTGGTGTCGGTGGATCCCCTTGCGGTAACACCGATGGGACGGCTCGGGGAGCTTCGGATCCGCCTGGAACCGAGCGCCGTCACCCGCCCAACGGGCGATCAGGATCGCACGGCGGCGGGTCTGGGGAACCCCGAACTCCTCGGTGTGGAGGACCTCCGGTTCGGCCACCTTGTAGCCCTTGCTCTCCAGGATCTCGCCGAACGCCCGCCAGACCGGAAGCACCGCGGGAACCTGCTCGAGGACGATCACCTGGTAGGGCTTTCCCCCGGCAAGCGCCTCGAGCGCCCACCTCAGCGGCTCCAAGACCAACCCGGTGCGCTCGTCGCTGAGTTGCCCGAGATCTTCCCGGATCGCGGCGAACTCCTCGGCCTGTCGGTCCAGCTGTACCGCGGCGTAGCGCTTCGCGAACTCGAGAACCTGCTCCAGCGCCGCCCGGCCCTCGCCGTTCCCGGCGACGGTGAAGGTCTGGCAGGGCGGTCCGCCGACAAGCACGTCGGCTTCCGGGAACTGCGACGGATTGTACTTTCGTACGTCTCCGGTCTCCGTCGGCAGGCCGGCCGCTCGACGCGTGGTGCAGGCGTCCTCGTCCCACTCGATGCCCATGACCACGGGAATGTCCAACGCCTTCGCCGCCATGTCCAGCCCCCCGGGGCCGGCGAACAAATCGATGATCTTGAAGGGCGTGGACACGCGGTTCCTTGCAGGATGGTAGGAGGGGGAGCGCCGGGTTCCCTCCGGTCTCCCTCGTCACGAACTGGAGCGGCCCCTATCGTAGCCGGCGAGATGGGGTCCTCGGACCAGGTGGCCGACATGCGCGAGCCGGTCGGGGTCCGCCTCGCCCACGCCGAGGGCGTGGGCGAGTGCTCGGCCTACGGCCTCGGCCAGCGGCGGCGGCAGCGCGTGGCCCACCTGGCGGTATTCAGAGGTCTTGCCGCCGGCCAGGGACCAGTCGTCGGGGATCGCCTGGATCGTGGCCGCCTGCCGCACGGTGAGCTTGGGGTGTGCGGCCACCGGGAAACCGACGCTCGGAGGCTCGTCGGCGAGGCTGTTGCCGTCGACCCCCAGCGCAGCCCATGCTCGCTTGCTCCCGGTCGGCCCCAGGTCCGCCCCGCCCCGGTTCTCGGAGCCACCCACCAGTGCCGGTGCCGGGCGGTCGGCTCGCGCGGACCAGGCTTCGGCACCGTCCCACCCGTTGGCGGCCATGGAGTCTCGGAGTACTTCGCCGACGGTGGGAGCCGGATCGCCGGTCGGTTGCGGCCACGAAAAGGCGAGATCGTAGGCGCCGGGGAGCGCGACGAGGAATCCGCTTCTCCGGTTCTGGGGCACTCCGAAATCGACGGCGTCGAGGACCGCCCAGTGAGACCGATAGCCGGCCCGGGCGAGCTCGGACTCGATCCAGGCTCGGTCGGTGGCGAAATCCCTAACGTCGACGATGTCGGCGAGGTTCTCCAACAGGAGGGCCTTGGGTCGGACAAGGGTGACCAGACGTAGAGCGGCCGTGAGCACCTGCCGTGCTTCGGTGTCATCGGTCCGACGCACCGCACCTGCCGACTTGATCCGGGGCAGCCCCCCGGTGAGCAGGTCCACGTGCAGCGCCCCAGGGTGCTTCAAGGGGTCGAAGTCGACGATGTCGAGGCACCGCACGTCCCAGCCGGGACGGTTGAGGCGAATGGTCGCGCAGGCCTTCGGGTTGCGGTCGATCAGCATGACCGGGTCGAACCCGGCGCGCTCGAGGCCGAGGGCCTGGGCACCGGCTCCCGCGCAGATCTCCAACGAGGTGAACCGCCGCATTCCCTCACGCCGAGCCTCGCTCGCGTCATCGCCGGTGGACGACGCACACGCCGAGGGCTGTAGGACCGCTGGTTCGGACGCCGTGTGCGGCAGGGGCTCCGGCTCGCCGTCCTCCCCGGAGCCCGCCTGCTTCAGTGCGGTCACCGACTCCTCTGCCACGGCTCGAAGCTCGGCGTCGAGCGCCCACTCCTCGATGCCGTCGAACAGGACGAACGGGGCGAGACGGAGGAGCCTCTTGAGGAAGTCACGGAGGGCCTCCCGCTCGTTGAGTTTCGCGAGGTCGAGATCCTTCCAGACCCGGAGAATGGCCCTGACCAGGTGCGGGCTTCCACCGAGGGCGGCACGGCGTGCGTAGATCTGGTCGAAGGCGGCCTCGCCGAGGATCTTGAGCGCACCGTACGGTTCCGGGTCGTCGGAGGAGCGTACGAGTTGGGCCCGCCACCACAGTCGGCCGAAGACGTGTCGGGTGAGGTCCGTGCCGAGGACACGGTCCTTGGGCGGCTGGGGGTAGCGCCAGAAGGCGACGTCCGGGAGCACTACGAGTGCGAGGAACGCCCAGACGTCCCGGGAGGCGGCCTCGGCGGGCACCATGCCCGTCTCGGCGTGCAGCAGCGCGGCGAGTCGGAGGTCGAACTCGGCGTTTCGTGCCCGGTCGGATTCGTCGGGGAAGCCGGCGTTCTTGGCGAGGTCAACGACACCGGCACGAAGTTCCCGGAGTCGGTCGGCGGGGACCCGGTCACCGCCGGTCGCCACGTAGACCGCCGACTCGTGGGAAAAGGCGGCAGCGCCGGTCAGCTCGGCGATCGTCAGGCGCCGATATTCCTCGAACAACGGTGCGGCCTGCTCGGCGAGCAGCCGCGGGTAGAGGAAGCTCATCGTCACACCTCGAAGATCTTGACGGCCGCCTGCAGGTCGGAGGCGAACAGTGCGGGCGACTGCCGTTGGCGCAGACGGACGTCGGTGATCGACTGGTCCGGGAACAGCCGGTCGAACAGGCTCTGCAGCGTGGCGCCCAGAGAGCCGTCGGGGAAGTCGGCGTCCTCGGTGAAGTCGTCGTTGCCGAGCGCGTGCTCGATCATGATCCGTGCGGCGTCGGCGTAGACCGCCGAGAGCACGACCCGATCGACCTGACGCGGCTTGCCCGCGTTCTCGAACGCCGCGGTGGTGACCGTGTTCCGCTCGTTGACGAGCAGGAGGAGGGAACCCATGGTGGCGCTCTCCAGACCTCCGCTGATCCGAAGGTGCCAGGCCGCCTCGTCCGGGAAGGAGGTCCGGGAGAAGTCGATCACGGCCATGGGGAACTGCGGCGCGTCGCCCTGGAGGCGGAGCGACTCCCGGTCGCTCCACAGTACGGAGCCGGCCCGGCGGGGTGAGGAGGGACGACCATCGGTCCGGCGCTCGGCCAGGACGAGAGCGGTGTCGAGGAGTAGCAGGCCCCCCAGGTCGGCACCGCGGAGAAAGACGTCGATTTCCGCCGTGATCGTGCCGCCGTCGGCCAGACGCAGGCGACTCGCGGGCCCGCTGAGGTTGGAGCCGGTGGCCGTCCACACGGCGGCGAGGGTGAGGGCCGCGTCGGCCGGAAGGCCCGACTGCGACCGCGCTCGGGCCAGGTCGATCCGAACCGTCCTACGCAGGTGCAGGTCCATGTGATAGTCCCAGTCCGGCAGTGCCTCGGGCATGGGGACCTCGCCGTCCTCGGTCACCAGCGACCACGGCTCGACGGTGACGACGTCCTCGGACGGTATGCGATAGGGGAGGACGCGCCGAGTCACCGGGCCTTCACCGCCTCGACCTTGACGTCGATCTCGGTCATCGTGTCCGGGGCCGGGCGCACGAGGGCGCGCCAGACGGACTCGCCGCCCTCGACCACGCACGCATCGCCGGTGTGCAGGCGGCCGTCGCCGTCCTCCCAGCCCAGGAGCACGGGCATGCTCGCACCGACAGGCGGATCCGTCTCGCGGCCCCCGCTGCCGGGGAGTGTCACGGCCAGATCGATCCGTACCCGCTGCGGTCCGGGCACGGGCAGGCGGAACTCCTGGACGAGCACCGAGTCGTCACCTCGGTCGTCGTAGTACGGATCGCCGACGTACTGCACGCGCGGCCTACGGCGCATCGCGGCTCCCGCACCGTACGGCTGGGCATCGGCAAGCGCCTGTTGCCCGGGTCGGGGGTCTCCCGGCGTTCCCACTCCGTAGGGGCCCGGCGTGGCCGTGTCGGAGGGTGCCTCGTGAGGAACGGATCCCGGGTCGAATCCACTCCTCTCCTCCCCGTCCACCTTCCGTTTGAAGGCACGCACCGCCGTGCTGCCCGGTTTGGAGAAGGCGGTGGCGCCACCAATGCCCCAGGCACCCCCCACCAGCCCGGAGAACCGGGAGCTGGCCGCGCCCAGCGCGACATGGCTGGCACCGGGGCGGGTGACGCCTCCGAGGGAGAGCAGGCCTTCCAACGATTCGTTGATGCGCCGGAAGGTCGTCTGTACGAAGGTGCTCTCGGGTCTGTCGAGCGACTGCGGGTTCCACGCATCGTGCGTCGGCGGCTCGGCCTTTGCGTAGACCTCGTCCATGGCCTCGTCGGCCCGGAAGACGCCGGCGTAGCCCTGATTCGCGCTCGGCGGCTTGGGCCCGCGTCGATAGGTGACCACGAGTTCCGCGGGTCGCATCAGACACACGTGGTGCACGAGGTCCTCGATGTCGAGCATGCGTGAGGCGCGGGTCGGCTCCACGGGCGGCATGATCCTCTTGACCAGCCCCAGGCGCCCGAGATGCCGCTTGGGGCTCTTGCACTCCAGGTCGGTGCCGTCCGGGCCGATCATCGCCTCGTAGGCGGCGACGAACATGTTGAGCGGACGGGTCTCCCTCGGATCCGGTACGGGGAACTCGACGCCGTCGCAGGTGACGGAGAACCGCATCGCCGCAGGCCTGCCGGGGGTGGAGATCATCTTGGGCCAGAGGTGCCACGCGATGGTGTCGGCCAGGTACTCGGCCGCGGCGGCGGGCTCGAGCCCGTCCAGGTTCGGGTCAATGACGACGATGGTCGTCCCGGTCTCCTCCGGCCCGAACGGCCTGAGCCCCAGGCGCTGGGCGGTGGCTTCCGCAACCGGTCCCACCAGCGGCTCTACGACGTCTCCCGAGGTGTCGCCCCACCAGTGCCGACCGGTGTACTCGCGGCCCTCGGACCCGGCGGCCACGTAGCTCTTCCACAGGGTGCAGCCGATGAGCCGGGTCTCGTACCCGCCCTTCGGGGTGCGGCAGCGGGAGTGCACGAGGATCGTTCCGGCCCTGGACACCAGGTAGAAGATGCCCTTGCCGAACCCGTACGTGCCCCCGCCCAGCGCGGTGTCCCGCGGCGCACCTACGTTGCGGATGAACGAGACGAAATCCCGGTCGGGCCCTACGGGATCGTCGGCGCGAGTGGGTCCCCCGAGTCCTCGGGTGCCTCGATCGGAGACGACCAGGACGCGGGCCGCCCCTCGCCTCAGCGTATCTCGCAGCGGGAAGTCCTCCGCTCCGGCGGGCGCACCGTCGAGCAGGAGCTCTCGCCACGCGCCGGAGTGCGCCGGGCCGACCGTCCACATGTCGATCCGATAGTCGACCGGCGCGGGCGAAGGGATGAGGCGAGCGTCCCAACTGTTCTGGGCGGACTCACGCACCAGGATGGTGAGCAGATCGAGTTCCGGCCGTCCGAGTTGGTTGCGGATGCCTTCGGCCGCGGGCCCGCCCAACGGCGGATAGGGCTGGGAGAACCACCGGGGCGCCGTCACTCGGACTCCTGGATCATGTGGTCGATCGTCAGGGCGATCTGGTCGGCCGTCAGGGGGTTCGGAACTTCGCCGGACAGGTCGATGGTGTACTCGACGTCCAGAACCGAGACCGGTACGCCGGCCGCGATGAGTGTCCGGCCTGTCAGCGCGGGGAAACCGCCGTCGACGCCGTACCACCTCTCCTCGGCCACCGCGAAGGTCACGTCGCGGTAGCGCTCCGCGTCGGGCCGGTGGTAACCGGCTCTTGCAAGCAGGTCGAGCAGTGCGGTCTCGTCGTCACAGAGTCGAAGTGCCTCTTCCACCACCTCTGTGAACGCGGTGCCGACACCGTTCGCGCCGGTGCGCTGCAGCCGGAACCAGGCAAGACGGAGCGAGCCGTTCTCCGGCGGTTCGAGCTGGTCGAGCCCGTGGATCCGCGGCCTTCGTCCCTCACTGCTCGTACTCGCCTTCACCTCGACGGCCGTGCTCCCGCCAAGGAAGTCGTGGCAGTGGCCCTCGGGGCCGCGCCAAAGGCGATGTGCGCTCGGGTCCTTGGTCAGCAGCCGGTTGAGCACCGTCAATTCGCCGAAGAGGCCCGCCAACTCCTCCGGCCCCAGCGGAGCCGACTGTGTGAGGAAGAGAGCCTTCCACCGGTCGATTACACGGTAGAGCGCCTTTACGGGGTTCTCGGGCGACTCCCGCACCGCGTCGAGCACGTCGACACACAGTTCCGTGAACAGGTCGTCGAGGTCGTCGCGCAGGCAGGCGAGATCGACATACGTCTGGTAGGTCTCCGCGTCTTCCAGCGGTAGCTTGCGCAGCCGAAGGACGGGCCCGTCCAGACCCGAACGGACCTTGCGGTGCGTGTGTATCGGCACAAGGACGTGGCGGTGCCCGTCATGGTCGACGGCCACCGCCAACGGCCCGCTCTCGACCACGACGGGCAGCTCGGCGACCCGCAGCCGACGGTCCCCCGTCGGCTGCTCGGCCTCCAGCTCCGACCACAACCGCTCGACGAGACCGTGGAGCTCGTCGTCGCTCATGCGTCCTCGTCGTCGAGGACGCTGTAGTCCTCGTCCTCGATCCGAACATTGGACAGGTTCGCGGATACGTAGCTCTCGACCGTGCTGTCACCATGACGCGGCTCGGGGAAGACCAGGCCGACACCGATGACGTGGTCCTCCGCGTTCAGAGGCACACGCAGCCTCTTGGCCGGGAGCGGCTCCGACACCTTGTCGATCGGGTACAGGACGAGCAGACCGGTGTCGGGAAGCTGCCTCCGGCGCTCCTCCATGATGCCCTTCTCGGTCAGTTTCCCGGTGTCGCCGGCCAGGTCCACCGCGGCGTCCCGACGGCTCATCAGCGTCTTGATGTCGGCGAAGTCCGGTACGGGGTTAGGGAGATCGAGACGGGCACGGTTGTTGCGCCCGACGCTCACGCCGGGGGCGAACGCGAAGTCCTCCCCCTTGGGATTACCGACGATCGCAACGTTCCACCGGCCCAACGATCCGGCCTTGGAGACTCGCTTCCGGATGTAGTCGATGATCAGATCGGCGTCGTTCTCCGGGGACTTCTCGTGGAACCGGTAGGTCGACAGGAAGTCGATCACGAGGTCGTGCGGCACGTCACGGAAGACGTACCGGCCCTCTGCCGGGCGCTCTTCCGCCCTGACCGCGTTCGCGACCGAGGCCTTGATCAGAGCGCGCGCGGCGTCCGCGTTCCGACCCAGCCAGCCGGCGTTGGTGTGGAAGTAATGGGTCTGCACCCGCTTCCCGCCGTAGGAGGAAGCCGCCGTGACCGCGTCGCGCATCTTGGCGGCCGCGGTCACCCGCAGGGCCGGGTGCGTGCGCAGGCGGACGGCGAAGGTGAGCGGGGTCTCGTCCTCGGTCATGTAGATGTCGATGTCCCGGCGCATCTCGGTCTCGACGGTGGCCAGGTGTCGGAACCACTCGGCCAACTCATCGGTCATCCAGATCCGCGGCAGGTCAGCGTATCCCTTCCGGAAGCCGAACCAACGGCCCATCTGCAGCAGCGTGTCGTACGCCGACACGGAACGGACGAAGTAGCTGACTGACAGACCGTAAAGCGTCAATCCCCGCGAGAGGGTGTTGCCGCCCACCGCGATCGCCACGACCGGGCCGTTCTCGTAGTCGAGGCGGTCCTCGCTGCTGGAGTTGTCCATGATGACGCGGCAACTCTCGAGAACTCCCGACAGTTCGGGCAGCAGCCGCTCGAACGGCACCTTCGTCTCGCCGAAGTCCTCGGCCGGCACACGCTCGGTCTCCGACTCCCACAGATCACTCAGCCGCGCGAGGAAGTCGGCGTCGCCCGCGGACAGGGAGCGCTCGAACCGGTCACGCAGATGCTCCAACGGCCTCTTGAAGCTGTTGTGAACCGCGGTGTTGACGCTGGTGTGGATCAGCATCGTGTTGTGTGGATCGCCGGTACCACGAACGCGTCGGGCGGCGGTGACCAGCCAGAAGTACTCGACCGCCCGACGAAGGGTGTCGGTGATGAAGGGCTCGAAGCCCTCCACGTCGGCCCGGGTCTCCGGACGCACGGCCGCCACGTCGTCATCGGGGACCGAGCGGATCATGTCGTAGCCGTCGTCGACCTGCTCCGGGTCCTCGCCGTCGAGGGCGTATCGGCCGAAGAGGACCTCGGTGCCGAAGTGCCCCTCCGGCTTGGGGAGGTTGACGACGAAGTCCTTCGGATAGAGGTCCGCCGCACTCGGGTCGATCAGCAGGTTCGCGAACGGCGATGCCGTGTACCCGACGTAGGCGGACCTCGGCAGGGAACTCATGATCCCCAGGATCAGAGGGTTGATCGACTTCGTGGCCACGGTGGCCTGGTCGGCCTCGTCGTCGATGATCAGCGCGGGGCAGTCCTCGAGGTAGTCCGACGCCTTCTCGAGCCACGCGGCCAACTTGCGCAGCACCGTCGCATTCTTCTTCACGACGCACAGCACGTGCGTCCTGTTGTTCCGCCCGAAGTACGACGCAGGGTTCTCCCCCGGCGTGAAGTCCTTGTCGAGCCCGGTCAGCTGGGACCACAGCGAGGGGTTCGGCTCCACCAACTGCTGCACGAGTCGAGCCTGGGTCTGACGCCGGAGCCCGTTGTGGATTCCCGCCAACACGATGAACAGCTTGTAGCCGCGATCGGCCGCCTTGGCGACGACCGATGTGAAGTTGGTGGTCTTGCCGGACTGCACGTAGCCGACGACGAGACCCCGTGTGGAGAAGGCCTTCTGCTTCGGGTGGTTCAACAACGAGACGACGCGGGTGGAGGAGTCGTCGAGACTCCGGATCGCGGGCTCCGGAGGCCAATCGTCCTTGCGAAGCAGGTCCGTGATCGCCGGCCAGCACTTGTCCTTGGGCTGCGGACCCGTGTACCACGTGTCGCGGTTGCCCAGGATCACCGCGTGGGGTTCCTCGAGCTCCCTGATGCGGACCGTCTGCTGCTCATGCCGCTCCCGGATCCGCTCCACGATGTCCGGGCTGATACCGAGGCGCTCCAGTCGCTTGACAGCCTCCGAAGGGGGGAACGAGTCCAGAAGCGCCTTGAACGTGTCGTACATCTCGTCGAATTCATCGGTCATCAGGTTCGACCGCTCTCCGTTCCCGTTCGATCCAGCCAGCTCTGCAGCCGCGCGTCGAGGCCTCGCGACACACGTCTCGTGGAGACTACGCACCCCTCCAGGCGCATCCTCGCCACATCGCAGGTACACGTTAGTGGTCGCACAGAGGTCCGGGTCGTGATTAGCGAGGTTTCGTCAGTGCCGCTCACCGCCGGGTATGTGCGCGCATCTACAGCGAGAAGGAGACCAGCACTTGGGAGACCCGCCCACTCACCGACACGGCATGACCCCGCCAATAACGTCGGTGAGACCGGATGGCAGTGGAGATCGCCTACGAGACGCACTCCACCACCGCCGACAACGAGGCTGGCATCGCCACCGGCCGGCTCGCAGATGAGCTCTCGGAACTGGGCCGCCGCCAGGCTCGGGAACTCGGCGCCCGCCGACCAGGCCACGGCTTCGCGGCCGCTTTCGTCTCTGACCCGCACCGCGCCGTCCAGACGGCCCGGATCGCGTTCCGCGACGGCCCACCCCTCTCGATCAGGACAAGCGGCTGCACGACTGCAACCACGGTGATCCCAACGGAAGCCCACTCCCCCACGTCTCCGCTCAACCAGCCCGGCACATCGACGAACGGTTCCCCGGCGGCCAGGGTTACCGCCAGGTCGTCGGGGCCACCAACGCCTTCCGCCACGACCTCGTTTCCGGGTGGGAGGGCAGCAGAATCCTGGCAATCGCCCGCTCGGCCTTCCGGTGGCACCCTTCCCCCCGGACGGCCGTCGAACGACATGCTCGACACACCGCCCGCCTGGCGCCCGGACTGGCCGGATACGCTGCTGGCCGACTGGACCGACTCAGCCGGTTGCACCTGGACGGAGCCGCTCCAAGACTGGATCGTGCCGGCCGCGCTTTCCTCCCGTTCCGGCAGCGGCCCCGTGATGGGCTGCTGCAACGACCCCGAGGCCCGTATCGTCGGTGCCGGAACGCATTCTCGGCAGTGGGGACAGGCGAGTGGCAGTGAAGCGCGAGGGCGGGCCGTCGAATAGATCCGTCCCCGATCGTTCGTGGCGTCGCAAGCCCGGGCTTGACAGGGCACAGCAGTCTCGGGAGCAGAACCGGGCCGCCGGCGGTGCGGAGCGCAGGCTGGTGGATGCTGGCGAAGGGCTTCTCCAGCCAGCGACCGTAGTGCTGAACGCATCCCCCCGAACCGGACGGGTCAGGGCCGTTCTTCGCTGGTATGTCGACGGCCGATCGACCACGGCGGTGCTGGGCGACGTCGACCGCCCCACCCGAGCGGGAAACCTACGCGAAGGGTGGCGGCTGGCCGAAGAGGCCGGCTTGCTCTCGAGCGCGCCGGTCCCGGAGAGCTCATGGGCGTCGTCTCCCGCGACGCGGAAGTCGATGCGCGCGAACAGGGCCAAAGACACCAAGCCCGAGCTGCGACTTCGGTCGCTACTGCACCGCGACGGGCTCCGGTACCGCGTCTCGGTACGCCCGGTACCAACCCTCCGTCGCACAGCGGACGTGGTGTTCACGAAGGCGAAGGTGGCGGTCTTCGTGGACGGCTGCTACTGGCACGGCTGCCCGGAACACGGAAGCCTACCGGCAACCAACCGCGGCTTCTGGACGGAGAAGATCAAGGGCAACAAGGCCAGAGACGCGGAGACGGTCCGTCTACTGGAACAGGCCGGTTGGAAGGTCCTTCGAATCTGGGAACACGTCCCTCCGGAGGAGGGGGCTCGCCTCGTAGCCGAGACGGTGTCCGCGGCCCGCCAGGAGGCCCGCGCGGCGCGGGGATCAGAGAAGGCGGCCGTTGAGTAGGTCGTCAAGGGCGTCGGCCTCTCGACGCAGAACGATTCTGCCGTCACCGTCACTGTAGGCAAGTAGCTGTGCACCGATCGAAATCCCGGCTTCGGCGAGGACGCTCAGGGGGAGTTCAATCAGACCACCCTCTCGAACAACGACTTCAGCAGGTTCCCGAATCATGACGCCCAGTCTGTCACGGTCATAAAGCCCGACAGCCGCTACGACGTCGGCAAGCTCGGTGGTTGCCGTCTACCGCGGCATCAGTCGACCGCCGCCCGAAGCCGGAAGGACCCGCCCACCTGCGCGGCCTGGCCGTGGACGGTGATGACGCTCCCTGAAACTGGCTCTGACCGGAGTTCCGGATGCTGTTGGTGATCTTCATGAGTGACGGGTTCGAGTCCCGCCACTCAGTTGTTGGCACAGTTGCTGGAGGCGGGTGGTCGAACCTGTTCGATGGCCCGCCGCTCCACCATCGTCACGGTGCTGGCTGAGAAAGTGTTGGGTAATTGATCGACTGCTTGGTGTGATGTGCGGCCGGTGATCTTCGTGGTCGAGGAGCCCGCGAGGATCACCGGTATGTGTGTCTGTTCGTGCAAGCCTTCGTACGACTCGTCGTTGACGGATGCTCAGTGGGCGATGATCGAGCCGCTGCTGCCGGGGCGGGATCCGCGCAGGGGCGGCCGGCCGCTGAAGTTCCCTCGCCGCCTGGTCGTCGACACGGTTCTGTACGTCCTGGTCAGTGGTTGTGCCTGGCGGCTGGTGCCGCACGACCTGGCGCCGTGGGACGCGGCCTACCGGTGGTTTCGTGCGTGGAGCGCCGACGGGACGTGGGACCGGGTCCACGACGTGTTGCGTGACCGGGTGAGGGTCGCGGACGGTCGGGATCCGCAGCCGTCGGCGGCGGTGCCGGACTCCCAGTCCGTACGCAGTCACCAGGGCGGCGAGGCGATCGGCTACGACGCGGGCAAGCGTGTCCGGGGCCGCAAGCGGCACCTGCTGGTGGACAGCTGTGGACTGGTCCTGAAGGCGGTCGTGCACTCCGCGTCCGTCCAGGAGCGGGCGGGCGCGAAGCTGGTCCTGGCCGGCATCCGTGGTCTGTTCCCGCGGGTCGGGCTGGTCTGGGTCGACGGCGGCTACGTCAACGCGATCGATGCCGGTCTGGTCGGCTGGGCTGCCGCGCACGAGGACCTGACGGTGGTGGCGGTGCCGCGCAACGCGGATGTGAAAGGCTTCCAGGTGCTGCCCCGCAGGTGGGTGGTCGAGCGGACATTCTCCTGGCTGGGGCGGTGCAGACGGTTGGCACGGGACTACGAGCGCAAGACCGCGCACGCCGAAGCGATGATCAAGGTCGCCATGATCCGCCTGATGGCCGCCCGCCTCGCCGGCGAGGAGGTCGAACCACGCGGCCCCATCGAGACCGAAGCAGCCCGCCGCCTCGCCGATGACCTCAAGAACGAGTAGTCACCCGCTTACCCAACACTTTCTGAGGCGGATGATGTTGGTCCCGGCCGCGGTGAGGACATGCTGGACGTGGGTCTTCGCGGCGCCGCGGTAACGGCAGTTGCGCAGGCCGTTGGCGTGGACGGTCTCGGAGACGGTGGCTTCGCAGCCTGCCCGCATCGCGGGTCCCCTGCTCTTTCCTGACACGGTTCTGGATCTCCTGCAGGGGCTGCGGCAGCAGCAGGAGGTGGCGACCCTTGCCGTCGACGTTCCCGGTGCACCTGGGGCGGTCGTCGCAGGCCCGGCAGACGGCCCGGGGGAAGAGCACGGACAGGCGCGGCTGGCCGTCGGCGAGTGTCGCCTTCCAAGGTGGGCTGGTAGCGCCGTTGGGGCAAGTGAGCGTCCGTTCTTCCCAGTTGGGGAGGAAGTCTTCCTTGTTGAAGCCCGGCAGGGCTCGTGTCCTGGGCGGGAGCCGGACCGGGCCGACCAGGTCGATCCCGTACTCGGTCCTGGCCCGGTGGATGGTGGCCGGGCTGGTGTAGCCGCCGTCGACCAGGTGCTCGGCAGGCGCCAAGTCGCGTGCGGCGAGGTCGGAGTGGATCTGTTCCAGGGTGTCGATGTCCTGCTCGGGTGCCGGGGTGGTGGCGACGTGCACGATCACGTTCGGCAGGCCGGTGTCGCAGGTCTCGGCCTGGTGGTCCTTGTAGCCGACCCACTCGGCCTTGCCGGGTTTGTGGCTGAAGCGGGCCTGCGGGTCGTGGGGAGAAACGATCTCCACCGACGACCACGGAACCCGGGCCGAGGCGGGGTCGGGCCGCCCGTCGGAGGCTTCTGCGGCCATCGACCGCCGAGGACTGTGGCGCCGGCTCAACCGGTCGCGGGTCTGCTTGGGCCCGCGCCAGCCCAATCGTCCTTCCTCGTCGTACCAGTACTGCTGGACCCAGACCTGCCGCAGGACCTCCATCTGCGGCAATGCCCGCAGCCGGGCCGGGGCACCTGCCCGAGGACGGCTCGCAGCAGCCGCATTCCGTCCTCGCCGACCGTCAGGGCGTACCGCTCCCGCTCCTTACTGGGCGTTTCGTCTCCAAGTGCACTGATTGATACCGGTATGCGATGTGCCTGACTGGCTGTTCCGCCGGTACGCCATGTGCTGCTGTTCTGGGAGTGCTGCCTGCATACGAATGCCCGCCGGAACTGCGCAGTACGTCCTGTCTCATCCCAAAAAGCCGGGCTGGAGCACGTTCGTCCCGCGGTTCCGACGGCCTCTGGCCAGAAGCGAGGTTCCGCAGTATGCCGTCATCATGACGGATCGTCGACCGTATCCCAGCGACCTGTCCGACGCCCGCTGGGCCTTGGTCGAACCCACCCTCTCCGCCTGGCGCCGCGCCAGGACCGAACGTGCCCTGGCGTTCGGCCGGCCACCCGAGCACGAACTGCGGGATCTACTGGACGCGATCCTCTACGTCGACCGCACCGGCATCCCCTGGCGCTACCTCCCGCACGACTACCCGCCCTGGGAGACCGTCTACGCCTACTTCGCCCGGTGGCAGAAGGAAGGCGTGTTCGAGCAGCTCAACGGCCTTCTCCGACGTCTGGTCCGCGCCGCCGAAGGCCGTGATCCGGAGCCGACGGCGTGCATCATCGACTCCCAGAGCGTGAAGACCTCCACGAACGTTCCCGCCGCCACGCAGGGCATCGACGTCGGGAAGAAGATCGCGGGCAGGAAGCGCAACATCGTCACCGACACGATCGGCCTGCTGCTGATGGTGCTGGTCACCGCCGCGAGCGTGCAGGACGGTACTGCCGGCCGGCAACTGCTGACCGTGGTCGCCACCAACCACCCCACAGTCCACAAGGCCTGGGCCGATATGGGCTACAAGAACGCCGTCGTCGAGCACGGAGCAACCTTGGGCATCGACGTCGAGATCGTCCGCCGTGACCCCGCCACCAGGGGATTCGTCGTCCAGCCCCGACGCTGGGTCGTCGAACGCACCCTGGGCTGGCTCATGAACCACCGCCGCCTGGCCCGCGATTACGAAGCCCTCCCCGCTCGCTCCGAAGCCATGATCCACGTCGCAATGATCAACCTCATGACCCGCCGACTCACCGGCGAGAGCACCCCGACCTGGCGAGGAACGTGAGCCTCGGAACCAGGGACAAAACGCTCAGTTACTGGGCGTTTCGTCTCCAAGTGCACTGATTGATACCGGTATGCGATGTGCCTGACTGGCTGTTCCGCCGGTACGCCATGTGCTGCTGTTCTGGGAGTGCTGCCTGCATACGAATGCCCGCCGGAACTGCGCAGTACGTCCTGTCTCATCCCAAAAAGCCGGGCTGGAGCACGTTCGTCCCGCGGTTCCGACGGCCTCTGGCCAGAAGCGAGGTTCCGCAGTATGCCGTCATCATGACGGATCGTCGACCGTATCCCAGCGACCTGTCCGACGCCCGCTGGGCCTTGGTCGAACCCACCCTCTCCGCCTGGCGCCGCGCCAGGACCGAACGTGCCCTGGCGTTCGGCCGGCCACCCGAGCACGAACTGCGGGATCTACTGGACGCGATCCTCTACGTCGACCGCACCGGCATCCCCTGGCGCTACCTCCCGCACGACTACCCGCCCTGGGAGACCGTCTACGCCTACTTCGCCCGGTGGCAGAAGGAAGGCGTGTTCGAGCAGCTCAACGGCCTTCTCCGACGTCTGGTCCGCGCCGCCGAAGGCCGTGATCCGGAGCCGACGGCGTGCATCATCGACTCCCAGAGCGTGAAGACCTCCACGAACGTTCCCGCCGCCACGCAGGGCATCGACGTCGGGAAGAAGATCGCGGGCAGGAAGCGCAACATCGTCACCGACACGATCGGCCTGCTGCTGATGGTGCTGGTCACCGCCGCGAGCGTGCAGGACGGTACTGCCGGCCGGCAACTGCTGACCGTGGTCGCCACCAACCACCCCACAGTCCACAAGGCCTGGGCCGATATGGGCTACAAGAACGCCGTCGTCGAGCACGGAGCAACCTTGGGCATCGACGTCGAGATCGTCCGCCGTGACCCCGCCACCAGGGGATTCGTCGTCCAGCCCCGACGCTGGGTCGTCGAACGCACCCTGGGCTGGCTCATGAACCACCGCCGCCTGGCCCGCGATTACGAAGCCCTCCCCGCTCGCTCCGAAGCCATGATCCACGTCGCAATGATCAACCTCATGACCCGCCGACTCACCGGCGAGAGCACCCCGACCTGGCGAGGAACGTGAGCCTCGGAACCAGGGACAAAACGCTCAGTTAGTCTCCCTGGGCAGCCGGTCATAGCGCACCGGCCGCCCGTAACGGCGGGCCCACTCGTCCGCGAGCAGGATGGACAGCCATTCCCCGTCAGCGCGTGCCAGCTCTTCGAGGGCAGCGCGCAGGCTCTCGCCGACCAGCTCGATGCGGTCCAGGCTCCGCACCGCCGCCAGGACGTGGGTGGAGTCGGTGCGCTGACGCCCGCGGCGCTTGACCAGGCCCGCGTCGACCAGCCGGTCCACCATCACCGTCAGCAGCCGGTCCGCTCGGTCGCCCTCGGCCATCCGGTCGCGGAACTCACTGAGCACCGAGAAATCGAACCCGGGATCGTCCAACTCCAGCCCCAAGCAGTAACTTCCAGTCCAGACGGCACCGGACCGCTTCTGCGGCCTGCCGGTCCGTCAGGTTCTCGGCGTACTGCAGTACGGACACCAACGCGAGCCGCGCCGGCGACAGCCCAGGCCGCCCGTCGACCGGGTACCACTCGGCAAAGTCCTCATCGACGAACAGCCCGTCCAGGCGGTCCCGCACCCACATCGCCGCAGTCCCCCGAGGATTGCTCGCCCGCGCCATCCGCACGGTCAACGGCGGAATCTCTCGCCCCGGCCACGAGCCCGTCGCCACCGTAACCAGCCCCCTTCAACCTGCTCGGACCTCCCGTTCAGGACAGCAGGTGGACAAGGCCAGTGACGGGCAAAGCCCTCAGCCTCACTCTCGCCAGTGAAGATCACCAACAGCATCCGCAAACGCGGTCAGAGCCAAATCGCGGATTCTCATCAACGGCAAGAGCCTGCGCGGCGCGGCCAGGGCGAAGAGCCGCAGGATCCACCTGCTCGCCGCGGTGGAACACACCACCGGCCTGGTCCTGGCCCAGCTGGACGTCGCCGAGAAGACGAACGAGATCACCTGCTTCCAGCCGCTGCTGGACACGATCGCCGACCTCGCCGGGACCGTGGTCACCAGCGACGCGCTGCACACCCAGCGAGAGCACGCCGCCGACCTCCTGGGCCAAGGCGCCCACTACATCGTGATCGTCTAGGGCAACCAGAAGCACCTGCGCAAGCAGCTCAAGTCGCTCCCCTGGAAGCAGATCCCGCTCCAGGGCCGCACCGGGAGCAAGGGCCACGGCCGCTCCGAGATCCGCCGGATCAAGGCAGCCGCTTTGAACAGTCTGCTGTTCCCCGGCGCCCGGCAGGCCATCCAGATCAAACGCCACCGCACCTGCCGCAAGACCGGCAGGACCACCGTCAAGACGATCCACGCCGTCACCAGCCTGACCACCGAGCAGGCCACGCCTGCCGGGCTCGCCCGGCTGGTCCGCGACCACTGGGGCATCGCGGCCCTGCACCACATCCGCGACACCACCTTCGCCGAGGACGCTTCCCAACTGCGGACCGGCAACGCACCCTGTGCGATGGCCACCTGGCGCAACCTCGCCGTCGGTTCCATGAAGCTGACCGGTATCACCAACATCGCCGCAGGACTGCGGCGCAACGCTCGCGACCCCCGACGACCACTCGCCCTCCTCGGCCTCGTGTGATCAAACCGGACGTCATCCGACTACGCCGAAGCCCTGCTGGCCTACCCGGTTCAGCGTGACGACGACGTGGCCCTCAAAGAGGTGAAGGCTGCGCTAGCCAGACACTAAGGTAGGAGGCTCCGTAGCTTGCAAGGACAGCATGAGACACGAGGTGTGAGCTGGTGGCTAACTTTCGCACGTCCGCGCGCACCGTCGACATGCTTGGCAGGCAACAGATCGCGGGGATCCCGACCGCAATCAATGAGCTCTTCAAGAACTCTTATGATGCGTATGCCACCACAGTGGTCGTGGATTGGCTGAGGGACCGTGAATTTTTGGTGGTTCGGGACGATGGCATCGGGATGAGTCATCGAGATTTCTTGGAACGCTGGCTGACCATCGGCACTGACAGCAAGACAGCTGGCGGGAGACTTGAGGCCCTCCCGATCCCGCCGGATGCCCGTCGACGACCAGTGATGGGGGAAAAGGGAATCGGTCGCCTGGCGATTGCAGCGCTAGGAGCCCAGACCCTCGTTCTCTCTCGGCGCCGTGAGGATCCTGGCCAGACCAGTGGCGAGGCCCCTGTGGTTGCGGCACTGATTCCATGGAAACTGTTTGAGATGCCCGGGATCACCCTGGATGACATCGAAATCCCAGTACTCAAAGTGGCGCCCCCAGACGCGCTCTCGAACGAGACGATCAATCGCCTAACTTCAGCCCTGGGTGACACGCTTCATCGTCTGCACGGCATGGCTGATCAAGAATTCCTGGATGTCATCCAAGCCGATCTCACGCGTCTTCGCGAGTTCGACTTGAGCTCACTGCGTCGACTTCCCGGTCCACAGATTGGCGCTCCGGGCAGCCATGGAACAGTCTTCATCGTGAGCCCAACCGATGAATCTCTCCCCATTGAAGTTGATGGAGATAGAGGTCGACCACCGGGAGAGCAGGCCAGCCAGCTGGTCAAATTGCTCACAGGCTTTTCGGACACGATGTCCCGAGGACACCGAGAGCCTGAGATGCGCACATCCTTCGTCGTGCGTCGAGATTCGGGTGAGGCAATTGACCTGATCGACGGTGACGAGTTCTTCACGGATCGCGACTTCCGAGAATCTGACCATGAGTTCGTGGGAGAGTTCGATGAGTATGGAACTTTCCGCGGCGAAGTCTCGATCTATCAGCAGAACCCAGTCGAGCATGTAGTGCCATGGCCGGCTGGCAAAGGATCACAGACGCAGTGCGGCCCGTTCAAGATCCGCTTCGGTTATGTCCATGCCGAACTTCGCCACTCCAGCCTTTCTCCCGACGTGCACGCGCAGATTAACCGAAAGCTGAACAAGGTGGCAGGCCTCTACGTCTATCGCGATGGGGTTCGAATTCTGCCCTATGGCAGCAGTGACATTGACTACCTTGGCATCGAAGAGCGCAGAAGCCGGAATGCCGGATACTACTTCTTCTCGTATCGTCGAATGTTTGGCGCGATTGAAATTTCGGCCACCGCCAACGCCAGGCTGCAGGAAAAAGCTGGGCGCGAAGGGTTTCGCGAGAACGTAGCCTACCGTCAATTCCAAGCGATCTTGATCAACTTTATTACGCAGCTTGCTGCGGACTTTTTCAGGTCAAGCTCAGATATGGGGCAAGAATTTCTTTCCAAGAGGGACGTGCTGGAGCGCACTGAGCAGATTCGGCGTAAGCGCGACAAGGTGGCCGGATCAGAGCGCGAAGCGTTTCGCCATGCGCTGCAGAAGGTGTTGGGTGAGTTCGCCGAAAACGAGCCTCAAAATCGGGCGCTTGACATCGTTCGTTCCGTAGGGCTCCAACTGTCGGATCTTGATCCATCGAGCCCGTCGACGCTGGATGAGGCCCTGGCTATTGAAAAGTCCGCCGAGTTGGAATTTCGAAAGATCGGCGAACGCTACACCGTCGAACGCCCGCGAGGTATTGGGTTGGATCGGGAAACCAGTAGGGACTGGTCCACCTATGAGCGCGAGCTTCAGTTTTTTGAGCGTGGTTTCCTGGCGTCGGCCGCTTCGGATGTCCGTGGAAAAGTTGCCGCAACGACGAGCGCAGCGGTCCCCTTGAATGTGCTGAACCAACGGGTCCGTCAGCAAGGCCAGAGGATGCTCGACGGCAACTTGAACGTGTGGATCCAGGGCGTGCAGGAGCTTCCACGGGACGCCGATGCTGTCGCACTCCAAGTGTTGGAAAGAGTTCGAGCGGCTGTAAATTCGGCGTCACGTCGGGCCAAGGATCTGGCAGACGAAATGAGCGCAGTCGCAGACAGCTTGGATCAGGTTGAGATCTTCGAGTTGCGTCAGCGAATGCTCGATGAACTGGATGCTGAACTTGATCGCCAGCAAAAGTCTCTCGCCCCAATTCGCGCGTACCTTAGCAGCTTCGAGGCATTGCTCAGCGGAAACGATGAGTTGGGCGATCAAATGGAAGCTGTAGAGGAAGAGGTGCTCGCGCTTCGAAATCAGGTCGACACGGACCTGGAGTTGACGCAGCTGGGTCGAGCCATCGAGCTAATCAATCACGAGTTCGCTTCGAGCATCAAGGCGGTCCGCCGCAACCTTCGGGCGCTGAGGCCGTGGGGAAATCGCAACCCTAAGCTTGGAGAGATCGAACGGGAGCTGGCTGCTGCATTCGAGCATCTTGACAACTACTTGGCCCTCTTCACTCCGCTACAGAGAAGGCTGTATCGGAAGCCGACACAAATCAGAGGCGCGCAGATTGAGCAGTTCTTGATGGATCTGTTTGGTGAGCGCCTCCGCCGGCATGACGTTGTCCTCACTGCGACAGATGCCTTCTCTCGGTTTGCGTTCTCCGGATATCCATCAACGTTTTATCCAGTTTTTGTCAACTTGGTGGATAATGCCATCTTCTGGCTATCGGACAGGCCGCAGCCACGGATCATCGAATTGGACGAGACCGCCGGAACATTGAAGGTCTCAGATAATGGTCCGGGTATCTCCATGCGTGACCGCGAAGCTGTCTTCGAGCACGGCTTCTCTCGCAAGCCCGGCGGGCGGGGCCTTGGTCTCAAGATCAGCAAGGATGTATTGCAGCGTTCGGGGTGGTCTTTGCGCGTTGATCCCACAGGGGGGCTCCCGTGGCCGCCTAGTGGCCTGCATGACGCGGTTGGGCCGGGTGGGGGGAGAGGTGCAGAATTCCTGATCATTCCTCCCGGCGACGAAGAAGATTAGTGGGCGACGTTAAGGTGGGGACACCAATGACTTTCAGTAAGGAATCCGAGCAAGTAGCACTGCAGTACCTGCAAACGGTCGTGGTGATCGACGATGGCCTCCTGCTCGGCGTTGAGGACGCATCTGGCGAAGCGGAGGTTGTGGATCCCGTCGACCCTCTGGAAGTTGATCCCGCGGAGGGCGAGGGAGAGACGAAGACTCAAGGGTCGGCCGGCCAGGACCTTGATGGCGCTCCCGACGATTTGCTGCGGGGTGAACAGCTAATTCGCGGCTTTGCGGAGAAGGGTCTGGTTTGCGGCCTCCTGAAGCCGTCCAGTGGTCAAGAGTTGGAAGATATCAAGTCCGGGCAGTACCAGCGCCTTTTTGCTCGTGCGGACGTCATGGTCTTGGACTGGTCTCTTGCTAGAGATGAAGGTGCCACAACCCGCAAGTTGATCTTGGACTTGGTGGGGAAGTCAGAAGAAAGAGTCAAGCGCCTGCGCTTGATCTGCATCTATACAAATAGTCCGAACTTGGCGAGCATCCAGGAAAGTATTGCCTTGGATCTCAGGGCGGATGGGATCAATAGCTTCGTCGGCGGCGAAATGGAGCGCGACTGGTTTGTGCAGGGCGGCGACTTTCGAATTGCAATCCTTGGCAAGACTGGAGTCAGTCGACTGCCGCATTTTTCGGAGGCCGAGGTCCCGGAGGGAGAACTGCCGAGCAGAATCGTTACTGAATTCACTCGGCTCGCCCATGGACTTATGCCAGCCCTGGCGCTGAACAGCTTGGCCATCTTGCGCGACAACGCACCTATGCTCCTACAGCGCTTTAACGGCAATTTGGATCCGGCCTTTGTAAGCCACGAGCTGCTCACAGGGCAAGGTAGGCGCTTTGCGGTTCAGCTTATTTCCCGGGAGATTCAGTCGATCCTCGAAGCTGCCGATGCGGGTTCCGTTCTTTCTCACCAAAACGTCAAGGCATGGGCGGCCACCAAACTTGAAGCGGTATCGTCCGACGAACTTGAAGTGAAGATGGGCAATAGTCGGCGAAAGTTCAAGAAACTGGATGTATTGACAGCGATTTCGCAAGAGGAATTTTCTCTTCAAACTTTTCGTGAACTTAAGACCACGGATGGACTCAAGCTTGGCGCGGCGAAGCTCGCCTCGCTCAGCTCGCTCTTTTCGCCGGATCCGGATGCTCTTGACTCAGACGAGCAGTTGGGGCTTCTCTCTTGTTTGAGTCGTGATCTTCACGGCAGGTACGACGGCACTCGGATGCCGACGCTTCAGCTTGGTTCCATCGTTGCGCAGCGTGAGCAGGATTCTTCGGGCGAAGTTCGGTATTGGCTTTGCTTGCAGGCGCTTTGTGATTCAGAGCGCGTGACCGGACCCAGAGGGTTTCCTCTGATTCCACTTCGTCCGGCTAGCAATGGAGCCGAATTTGACTTCCTGATTATGGACCATAGTGGCGTCAGGGTGCAGCTTTCCGGCTCATCGCGCCCATTTGAGATGAAGGTAGTCGAGTTCTCCCCGGAGCAGGGTGATGATGTTATTCGGGCTACGCGGCGAGATGGCGAACTTGTCTTCCAGGACTGCGGGCATGGAAGCTGGTACTGGGTCGCAGAGCTGAGGCCCGAGCATGCGCTTCGAGTTTCTCATCAGATGGCGAGCCAGATCAGCCGAATTGGCCTTGATGAATCCGAATGGCTCCGACTGAGCGGAAATAATAAGAAGAGCTGATCGGCTAATCTTTCCCATGGGGCCTGAATATCCCTCAGCTGGCAAGAATTGGCGACGTTGTCGGCAATGCTTTGCGAGCATCTGCCTCGGTGCGGCCGTAGAGGGCTGCTCTGGGGGACATGCGGATTTCGGGTAATCGACGGAAGCGCCCAGCCCGTGCGAGTAATCCATGTCAGGCACGGGCCAGGGCTTCGACAAAGTCGCCTGGCGTCTGGTTCGTGACGGTCCGTCGGTGATCCGAGTGGAAGACCGTGCCTGCCTGCGCATCATCGCCGATATCGCCCGCTCTTGACCAGCTTCGCGGGGCGCCGTTGCTGCCCTGCGAGGCGCCGCGCCTGCTGGAACGTCTCACCGAGGTGCCGGACCCGCGTGATCCGCGCGGAGTGAGCCACCCGCTGGCCGTCGTCCTCGCCCTAGCCGCATGCGCGGTCCTGGTCGGGGCTGCCTCCCAGGTCGGCGTCCGCCCCGATCCGATACTCCCTGCCCGGCAACGGCCCTCCGCAGCCAACTGCGACGGTTCTGCGACCAGGGCTGGAGATTCGCTGAAGGAGCGGTCACGTTCACGGGCGCATCCAGCATCACGATCGTTCGCTACCGATACCGCGGAGCACGCATCCCGGCTCCGTCCCTGGACCATCGAATCGGTAGCCCTCACAGGCTGACCGGCGGGCTAGACACGTGGAGAGCCGGATGCGGTGAAGTCGCATGTCCGGTTCGGACGGGCGGCTCAGGGAAACGGATCAGCGGTTACGCTGCCACCGCGCCCTGTGCCGACCGCACAGGGTCACGACAGGTCGCCAGCCGCGCTGCGCTGGCGTCCAGTGCAGCGCCGGTGCCTGACGGCCCGTCGGCCAGTAACCATGGCCGTCTGTGACGGGCGCAAATGCCTCCCCCAACATCCCGCACGCTCTGGCTGCAGGGGCTGCGGCTCGTTGGGCTTCCCGCAGGCGACCTGGAAACCGGACCGTGCGATGTCAATGCCAGCTGGAGCGACTGTTCTCGGGCCCGTAGGGGCTCCAACCGTTGAGGAAGGGCTTGAGTTCTTGCAGTTCGACCTTGCCGGGCCTGGGCATCGTGGGCAGGGTGTCGAGCGGGTCGATGGTGCGTACGTACTCGCGGGCCCAGGCGAGCCAGGTCCTTGCGGAGGCTCGGTCAGCCGCATCGTCGACGGCTTGGGAGGAGGCGAGCCGTTCCTCCAGGGCGTCGCAGTAGGTGCGCAGTTCAGTGCTCTCGCGCCACTGGTGTGCCTGCTGGCGCAACTGCTTGGCGTACTGCTCCTGGAGGGCTTGCTCCTTGGCCGCCGCCATCGCGGTCTCCCAGCCGACTCGGCGCTCCGCTTTCGCACGCTCCTCGTCGATGGCGCCCTGTCGGTCGTCAACGGCGCGCTGCTGGAGCTCTTCGAGGATAGTCGGCAGGAGCTCCTCCAGGCTCCAGCTCTTGCGGTCGTGCCAGGTGCACTGCCGCGTCGCCCGGTAGTGAGGGAGCTCGAGGGAGAGGCGCTCGGCTTTCTCCGGGTCGGTGGCCTGGGGAGCTTCCTGCTGGATGGTGACCGTGTAGGCGAAGCCGTCGATCACGATGTCGAGTTCGCCCTCGCGGCGAGAGTAACTCGATGGATGGCTGCGGCCGTTGTAGTAGTACGCGCGGCTGCGATGGCGTTCGGCCACGGGCTTCTCGCGCACCTGGTGGCCGCGCCGAACGGCTTCTGCTGCAAGGGCCTCGAACAGCAGTAGCGCCACGGCCCGGCCCCGGATCGCCGAGGAACTCGGCATCACGCCGAAGGAACTGGCGGGCATGCACCGCAGGTTCGAGGTCATCCCGGGCGCCCAGGCCCAGGTGGACTGGGGTGACGAGGGAAAGATCCTCGACCATATGGGCATCCCGAAGGTCTATTCCTTCCACATGACGCTGTCGTACTCGCGTGACCCGTTCTGCTGCTTCACCACCAGCCAGGACCTGCAGACGTTCTTCGACTGCCACCGCCGGGCCTTCGCCCACTTCGGCGGGGCGCCGATGACGATCGTCTACGACCGCACCAAGACCGTCGTCCGCCGGCACGTCGCCCCCGGCGAAGCAGTACCGCTGCATCCGGAGGCGGTCGGCTTCGCCGGCCACTACGACTTCGACATCGACGTGCTGGCCGCCTACCGGCCCCAGGGCAAGGGCAGGGTCGAGCGGCAGGTGCTGATCGTCCGTGACCACGTCCTGTCCGGCCGCTCCTTCTCCTCCGTCGAGGAGATCGACGCCGCGTTCGCCGCCTGGGTGCCGCAACGACGCGCCCAGATCCACAAGACGCACCGGGAGGTCATCGCCGAGCGGGCGGCCCGCGACCACGCGGCCCTCAAAGCCCTGCCGCCGACCCCCTACCTGGTGGCCGAACGACAGCTGCGGCACGTCGGCAAGGACTGCCTGGTCGCCTTCGACGGCAACCTCTACTCGGTGCCCGCCCGCCGGGTCAGCCCCCGGCAGCTGGTCGAGATCCGGGCTACGAAGTCCCAGGTCATGCTTCACTCCACCTCCGCGGACAGCGACGGCGGCACGCTGCTGGCCGCGCACTCCCGGGCGGTCGGCCGTGGTGCCCGCATCGTCGACGAGAGGCACTGGGACGGGCTCCCCACCGGGCAGGGACGCCGGACCACAACCGGCGACCTCCCCCTCCAGCCCCGCCATGAACGGCCCCTCGGCCAGGAAGCCGGCCCGTTGCAGGCCCTGCTGCACCGGGCCGCAGCGACGCGGGTCGAGGTCGGCCGCCGTCCGCTGTCGGTCTATGACGAACTGACCGGTACCCGCCCCTTCACCACGAACCGAGCGACGAAGGAATCCTCTTGAGCGAGCTGACCGGCAACCGCATCCGCACCACGGCCGGCAAGCTCGGCCTGTCCCATCTGGCAGAGACCATCAACGAGTTCACCCGCCGAGCGGACGAGGCGAAGATGGGGTACGTGGACTTCCTCGACCTGGTGCTGTCCGAGGAACTGGCCGTCCGCGACGACCGCCGCTTCCGCCAGGGCCTTCGGCTGTCCCGGCTGCCGCACCACAAGACGCTGGACGAGTACGACTTCTCGTTCCAGCCCGACCTCGACCCGCGCAAGGTCAAGGACCTGGTCACCCTGTCCTTCGTCGAGACCAAGGCGAACGCCGCCCTGCTGGGGCCGCCCGGGGTCGGCAAGACGCATATCGCCGTCGCTCTCGCGGTCGCGGCCTGCCGGGCCGGCTACTCGATCTACTTCACCAGCCTCGACGACATGGTCCGCAACCTCAAGGCCGCCGAGGCGGCAGGACGGCTGACCAACAAGCTCGGCACCTACCTGCGGCCGAGCGTTCTCGTGGTCGACGAGGTGGGCTACCAGCCGCTGGAACGAGCGGAGGCGAACCTGGTGTTCCAGGTCATCTCCAAGCGTTACGAGAAGGGCTCGATCATCCTGACCTCCAACAAGACCTTCAGTGAGTGGGGCCAGGTCTTCGGCGACGAAGTTCTCGCCACCGCCATCCTCGACCGGCTCCTCCACCACTGCGAAGTGATCGCCATCAACGGTCCCAGCTACCGGCTCAAGAACCGCCTCAAGGCCATCGCACGAGAGACCGAAGTGGCCTAGCTAGTGCTGCTCCGCGGAAGTTCGTGGAGGGTGTTGATCAGGCGGCTTTGAGCGGGGTGCCTTCGTAGGTCCACCGGTAGGGCCTTGCGGTGTCGTTGTGCCCGATTACGTAGGCCTGCAGCTTATCGATCAGGTCGTCGCGGCTGGAGAAATCGCCGTGCCGCACGACCCGGCGGGTCAGGGCGGAGAAGAACAGTTCGACCTGGTTGAGCCACGAGGCGTGCGGCGGGGTCCACCGGACGTGCCAGCGCGGGCGGGCCGCCAGCCACGCTCTGGTGTGTCTGGCCGTGTGAGAGGAACCGTTGTCGAGCACGACGTGGATCTCCTTGCCTGGGGCGATCGCCCGGTCGAGTTGCTCCAGGAACGCGGTGAAGGTCACCGCGTCGTTACGGGTGATCACCTCGGTGAGCACCTCACCGGTGCAAACATCGAGCGCGGCCACGAGGGAAGCCGTGCCGTGGCGCCGGTACTCGAACTCCTGCCTGACCGGCTCGCCGGGCCGCGCGGGACGCCCAGGACAGCGGCGCGAGCGGGCGGCGATCGCGGTCTTCTCGTCGATCGAGAGCACCACCGCTCCCTCGGGCGGATCCAGGTAGAGGGCGCACACCTCGGCGGCCCGCTGCCAGAAGTCCGGGGTGTCCCGCCGGGTGAGCCAGCCTCGCACCTTGTGCGGCTTCAGGTCTAGGCCGGCCAGGATCCGGCCGACCTGGGAGGCGGAAACCGGCGCGAAGCACGTGCCGGCCACCCGCCGGGCGATGGCCCGGTGCGACCAGGTCGACTCCGGATACGGCGGCGCGCTGGTCGCGGTGGCCACGATCGCCACGCGGACCTCGGGCCCGTACGATCGCGGCCGGCCCGAGCGTTCGGCGTCCCGCAGGCCGCCCAGACCCAGGGCTGCGAACCGCCCCCGCCACTTGCGCACCGTGTTCACGCTGACGTCCAGCTCCCGGGCGATCGCGCCGTTGGCGAGTCCGTCCGCCGCCGCGAGTACGATCCGGGCCCGCAGCACCACCCGCACCTCGGACTTCGCCGAAGCCACCGTCCTCACCAGCCGCTCACGGGCCTTGGCCTCCAGCACCACCGCAACCGCCGTCCCCGCCCGTCGCCCACCATGCACGGCCAACGATCATGGCGGGCCGCCGCCGCACCCGGCAGGATGGGCCCGTGCCGAAGAATCCGCCGGAATCTATGCAGCACCACCTACGCCAGCGCCTGAACCGCCACGCCCGCGAACGCTGGCCGCACGTGGACGCCATCGGGGTCCGCTTTCGCGCCGGATTCGCCTACCTGGCAGCCGAGTTGCCCGGTGGACAGAGCCTGCCGCTGTGTCGCCTGCGCTTCACCGGCGTGCTGCACACCTGGGGCTTCGCCCTCTACCTGGCCAGCAGCGACAGCTACAAGGACAACATCCTGCCCAGCGAACTACCGGCCGGCTCCCCCGAGGAAGCCCTCGACTGCGCGGGCGACCTCTACCTCAGCGGACTGGCTATCTGATCAACACCCCTCCACGAACTTCCGCGGAGCAGCACTAGAGCTGGTGTTGCGGCGGTTGAGCCACGACATCTCCAACTCCGACAGCGGAGGGTCAGGCGTAGGGCCGACATTGTTGTAGACGGCCACGGGATCGTCGGGCGCCGACCACGAGCCGACCGCCCACAGTCGATACACGTGCTCACCGCCCCCCTCCAGCGGCACGGTGATGCTCGCGGGCGCCGGAGGGCCGGGAACGCACCGGCCGACGTCATCTCCGTAAGGCCCGCCCCCGAAGACGGCATGCATCCAGCCGTGCGGTGGCGCCCCGCTCAGATCGAACACGTCGTCCATCGCCCACCACCTCCCAGTCGCGAAGATCGTAGTGCAGACGGTGAAGACCACCGCGATCGCCCGGACAGTGCCGCATCAGATGGGGACGTTCAACCGTACGCAGCTGAGGAGCTAGGGCACGTATTCGGTTGTGATCACGGGGCGGTTTTGGTGAGGTCTTTGATCCAGATCATCGCGCCGCGGAGGTGGAGGCCGGCGAGGTAGCTGCCGGGGGTCTTGTCGTATCGCGTGGCGATGCCTCGCCAGGCCTTCAGCTTGTTGATCAGGCGCTCGACGGTGTTCCGCTCCCTGTAGAGGTCGGTGTCGTGGCTGACGGGCCGGCCGCCCTTGCTGCCTTTCTTCTTCCGGTTGGCGGCCTGGTCCTTCTTCTCGGGGATGACCGCCTTGATACGGCGACCGCGCAGGTGGGCGCGGTTGGCGCGGGAGGAGTAGGCCTTGTCCCCGGCGACCGCGTCGGGCCGGGTGCGGGGGCGGCCGACGGGCCCGCGGACCCGCACCTTCTCCAGGACGGGGATGAACTGCGGGCTGTCGGCGGCCTGCCCCTCGGTCAGAATGAACGCCAGCGGGCGGCACCTGCGCTCGCCGGCGACGTGGACCTTGCTGGTCTGTCCGCCTCTGGAGCGTCCGAGCAGGGCGGCCTTCAGGCGGAGCCTTCGCCTGCGTCGGACGCGTCGGAGCTCGTCCCGTTCCGGGTCGTGTGCGGTGTCCTGTCCGTCTTGTCCCTGCGGGCCGCCCCTTTTTGCCGGGCCTTCTCCGCCTCCTCGGCGGCCTTCTCCAGGTCGGCGAGCGTGTCGGGGTCAAGGTGCATCCCGGCGGCGTCGTGGTGGGCCCGGATGGTGGTGGAATCCACGCTGACCAGCGAGAGGTCCACCTCGCCCCGTCTGGCGGCTTCCGTGATCGCGCCCTCCAGCAGGGCCTCGAACACCCTGGCGTCCCTCCACTGCCGGAAGCGGTTGTGGACGGTCGACCAGGCGCCGAACTCGCTCGGCATCTCCCGCCACTGGCCGCCCGTCCGAAACCGCCAGATCACGCCCTCGAACTGGCGGCGCAGCCGCTCGGGGTACGGGCCGTACTCGCCGATCGGCAGGTACGGCTCGATGAACTCCCACTCGGCATCGGTCAGTTGCACACGCGTCACACAACACGATCTACCGGATCAGGCACGAGCGCGAGGGCGAAACCCACAAAGTGATCACAACCCGATACGTGCCCTAAGGCCGTACGCCGACAGACGTAGACGAAATCGCGGTCGGACAGGTCCCGGTCCTGGAAGGCGGCGTGGTCCTCGCTCCACTGCTTTGTCAGCCGGGTGACGGTGGCCGGGGAGAGGCCGGCCGTACCGCCGAGGAACTGCTCCAGCGCCGGAACGAAGTCGCCGGATGACAGGCCATGCAGGTAGAGCAGCGGCAGCACCTCGGAGATCTTCGGGAACTTGCGGCACCACGGCGCCAGGATCTTCGAGGAGAACCGCTTGCGCTCGCCGGTCTCGTGGTCGACGCGCCGGTCGTTCACCCGCGGGGCCCTCACCTCGACCGGTCCGGCGGCGGTGACCACTGTCCGGGGCCGGTGGTGGCCGTTGCGGACCACCAGGCGGTGCCCGCGCCCGTCGGTCTCGGCCGCCAACTCGGCTATGTACTGGTTGACTTCCGCCTCCAGCGCGGCGGCCAGCATCCGCCGAGCTCCCTCCCGGACGATCTCGTCGATCAGGGAGCCGGACTGCGTGGAGCCGTCGTCGGTGACTACGCTGAGCACGGGCGTGCCTTCCCGACCCGCGCTGCAACGCGGGCCTACTCGGAGACCATCAAAGGATCATTCGGGAAGGTACGCCTTCCGCGTGCCTGTCGGCACTGATCCACAGGTCTCCAGCATTGCTCGTGTCATCGCGAAGGGCAGCGACCACTCGGTTCGGTGCGCGGAGCTGACTGGGAACCGGCACCGGGGCGAGGTCGGGCTGGGGCCCCTGGCGACGGCTTTCCGTGGCACCGTCAACGAGGCGGATCTCGAAGTCCCTGCCAGCGTTCCAGTGCCGTTGCGTCTCGATCCGCTTCCCTACGGGGAGGAGTTGGTGCCGCTTGGCGTACTCGATGAGGCGGCGCCAGGTTGCTATCGCCTCGTCCGACGGTGCGGTGACGATGACCTTGTTCTCGGCGACGAGGCGTGCCACCAGCTCGGTCGCTTCCGCCTTTCGGCGGGCGGGCAGCCGGATCTGGGAGGGGCCACTGCGCGCCGGGTTCTTGGGCTTCACTGTTGGCGGCTTGGGTGCAGCGGCTGCAGCGCCCTGGGTCGCGGAACCGGACGCTTTTTGCGGGGCTGCGGGGTGGGAGTCCGCCAGCCGGGCGGGGTGGTCCGGGTGCTGGCCGTGTTCGAGGTAGTAGCGGCCAGCGTCGGTGATCTGGGCTACCCAGCGACCGCCTCGGCGGTCGATGGCGACCAGTCCGAGGTTGCGCAGCGCGTAGCCGGTGGTGCGCGACTTCGAGTCGCTGGGCGAGTCGAGTGCGTCTCCGGACGCGATCCGTTGGAGCAGAGCGAGCTGGCCGGGGTTCAGCGGGTCCCAACGATGCATGACAGCTGCTTACACTCCTCCTGCACGGCTGTGCAACGCACGGCCCGGCGGCGCCCAGGGGCTCGATAGTTCAACGCCGCGCCTTTCTCAGCGGCGGCCGGTTCTGGTCCTGCCGGCGCTGGGGCGGTAGGCGTCCTTGACGATCTGCTCGAGGTCTTCTTCGCTGAACATGCGGTGACTGCCGATCTGCCGGTACGGGACGCGGCCCCGGACGGACTCCGTTCGCAGCCAGGATGCCGCGACGCCGAGGCGCTCGGCCGCCTCCGCCATGGAGTAGAGCAGAGGTCCTGCCCGCTTGCCGGTCGCAGCGGGGCTGGCGCTTTTGTCAGGTTTCGTCACGGGGAGGCCGAGCACGGCCGCGTCGGCCGCGGCGAGCAGCACGCCGAGGCCGCGCAGTCGGGCGACGTCTCCGACGCCGTCGTTGGGTCCGGGGAGACCCAGGGCACGGCGCCCTTGGGTCGCCGGATCGGGCGAGGGGAGCAGCAGGGCGGCGAGGCGGTAGTCCTCCTCGGTGAGCGTGGCCCCCGCGTCGAGTTCACGGCTCAGGCGCAGCCGCTCGCTCTGCAGGGCACGCTTGTCCATCGTCCAGAACCGTTCGCGCAGTTCTTCCCAGCTCGGGTGGGCCTGCACTACGGCCAGGGCGTCGGCTGCCGCGTCCGACCCAGGGTGCCCGCCGGCCTTGCGGTGGAGGGCGCACAGCGTCCCGCCCACCTCAATGGGGAGTTTGCAGGGAAAGCCGAAGAACGACGTCACCGGTGCCGGGCAGCGCGGCCTGTCCAGGGCAAAGGTAGCGTGCGACCCGTTACGGATCCGCTCGATCTGATCGGCCGCGTTCCGGATCATGTGCTTGGGGACGCCCCACTCTTTGGCCGCGTCACGAGGGGTGAGATGGTCGAGTGCCCGGATCCGTTCCATAGGCGTGCCCTTGCCATCCACCGCGCGCTCCCCTCGTCTGCAGTCGCCGAGAAAGTATCTTGGTGGCACTCGGCACAGGACAGTGTCATCTGACCGAGCTTGACGGAGAACTGTGATGATATTGACCGCTATCGATTGAATCTGACCGGCTGTCGGCGCCGGGCGCCCCGTCTCACTGCGTCCACAGTCAGCCGCCAAGGAGGCTACGGTCGACCGCTATCGCTCAGATCGGCAGTCGCAGGTCACGTCCCACGAAGTTCCAGCACCGCAGACCCCCACTCCAGGTTGGCCAGTGGTTCAAGTCCCCCCTCCGTATTGAACCCCTACACTCGCCTGGCCCGCTGTCAGCCAGACCTGCCCTCTTGCGGCACCGTTGAGAGTCTCCTCTCACAGTCGGGTCAGGGCACTGTCGCACCGCCGGCGGCGGAACACCCCGCAGGGCCTTCGACTCTGAGCCCGCGCGAACGCCGCGTTCAGCAGACGCCTTCCGCGTACGCGATTGCGGCCAGCGCGTCCTCCGCAGGTGCGGACGGCCCGAACTGGGCACGCGAGTTGATGGGCGTGTTCTTCGCCTTGGTAGGAGCGGGGTCAACCCACAGTGCAAGCCCGTACTCGATCATCAGGGCGCCCCGCCGTTCGTCCGAGAGACCGGACCACACCTCGGCAAGAGATCGTCCGGTGCGGTGCTCCTCCCAGTGGGGCTCGACCTGAGGGACCGTCTGAAGAACCTTCCGGCGCTCTACCAGGCGGGCCATCCGTTCCCGATAGTCGTCCTCGTCGTCGTCGAAGAGGCCTATGTCCCGGTCGTCACGTAGGCGCCTGATCGCAGCCCGAACCTCCGACAGCTCGCGGGAGGTATCACTTCCGGGGACCCATCGCCGTTCCACCTCCGGCAAGATGCCGTAGACGACGGGGAACTGCTCTCGCACCCAGTCCGCTACCAGGTCCGCCGGAACATAGACCGACGGGCTGTGCGCTGCAGTCTCCCGGCCTCTGCACGTGAACGCCCGCAATCCCGTCCCCGAGACCCATTGCTTGAGATTTCCGCCGCACACCGAGCACTTCAGGCAACCGGACAGCCAGTGCGAGGCGGCCGGTGCCTTGCGTGGGCCCTGCTCGAGTTCGGCCAGACATGTTTGCAGAGCGTCCCACTCATCACGGCTGAAGACTGGGTCCCAGACGAGCACGGGAAGCCCGTCGCCATTCGTCTGAACTTTGCCACCGGGAAGCAGGCGACAGCCGAGCATCGTGGGTGAAGCGAGAATCCGCTTCAGCGAGACTCCTCGCCACTGTGCGGCCTCAGCCTTCGCCAACCCCTTGAGTACGGCGCCACGCTGTCGGCTCGTCGGTTCTTTACGGTCGTTCAGCCGCCGGGCACACTCCGCCATGGTCGCTCCTTCGAGAACCCAGAGCAGCACCTCCCGAAGTACCCCGACCGCGTGAGTGTCCCGCACCAGCACCCGACCCTTGCCGCTCGGGTGGTCGGCCACAGTGAGGCCGTAAGGGATACGCCCGCCGTGGAAGCGGTTCTCCTCCTTCGCCTTCCGCATCGAGTCTGCGACCCGCGCCTTGATCATCTCGCGTTCCAACTCAGCGAAGACTGCGATCATCTGAGCCATCGCTCGACCGGTCGGGCCCGTCATGTCGATGGGCTCGGTCGCCGACACCAAGGCGACTCCGTGCTTGTCCAACTCCTTGACGATCTCGGCGAAGCCCAGGAAGGACCGGGCGATCCGGTCGATCTTCCAGACCATCACCGCGTCCATCCCTGAGAGTTGCTGGAGCAGCTCCTTCATCGCGGGGCGGTCCATCGGCGGGAGTGCCCCGGAGACACCCTCGTCGACGAAGGCGCCAACCACTCGCCCGCCGCGGCGCTTCACTTCCGCCCGGGCGGCTTCGTCCCGACGCTCGATCGACGTGCTCGCCTCGGTGGCTCGCGAGAGCCGCTCGTACAACCCGTACCTGTCCAACGTTCGAACCCCCAGCCTCACGTGACTGTCAATTAGAATTCTACGTCAGGTCGTACGCGGGCTTGAGGTCGTTCAGGAAGCGCATGAAAAGGGCTCTCTGGCTGGGAGAGAGGTACACCTCGGGCGCGGTTGCGGCGGTGCCGCGGGGCGCTCTCGGGCGCCCCGCACCCAACCGTCAATCCTTACGGATACCCGGGTCGAAAGCCAGTTCACGCCCCAAGCTTGAAGATCCACACAACGGCCCCGCGATCACCGCCGTTCAGTCCTGTAGGAATATCCAAACGACCGGCGCCTCTGGTCGATTCCCGGTCGATTCCCGGTCTTCCGTCCTCGACCGACGGCTCGCTCCGGATGATGGGAGGACCACGGCGATCTGGGGGCGGCCATGAGTGAGGACGGCAGCGGGGGAGTCCGCGCACTGCGGATGTGGGCGCGGGACGCCATCGAGCGCGCCGACCGGGTGATCCCGTTCACCGAGGTCGAATGGTTCAGCAGGATGCAGGCCTTCGCCGAGCCCGGCTTCATCGACCGAACGATCGAGGAGTTGACCCACCTCGAACCGCTGCTGCCGGCCCCGGACGACCCGCGCAACGCCGTGCTGACCCGCCTGGGTGTGCTGCTCGCCCTGCGCTACGCCGGCCCGGAGGGCGGCTCGGCCGAAGACCGCACGCGCGGGCTGGCCTACCTCGGGCAGGTGCGGTCGGCCGAGCCCCGAGCCACCGACTGGGAGCGGCAGGGGGCCGCCTTCGGCCTGCTGGCGCTGCGCAACCCCCGCCCCGAGCTGGGCCGGCGCGACGGCCGGCCGGCCGATCACGCGGCGCTGATGGACTGGTACATCAAGGACGGCGGTGCCTTCCAGGCCGACGACCTCCCGGAACTCTTCGCCGACGCGAGGGCCCTCCCGTTGCCCACCGAGCTCCGGCAGCAGCTCGACCAGGCTGGCGCCGGGGCGGCCCTGCTGTCGCACCTGCTGCGTCCGGGCGGCCCGACCGCGACCGCCGAGGAGGTCATCGATGCCTTCCCGGCCGACTTCCCCCTCCTCTCCGAGCTGCGCGCGATGCTGAACCTGCGAGACCGGCTGAACCACAGGGAGCCGGCCACGGAGACGTCCACGACGCCGGAGCCGACCACGGAGCCGGACGCCGGCCCGGCCCGGGGCCGGGCCCGCGTCCTGTCCCACCTGGAGTCCGTCCTGCCCGGCGCGCTCAGCGCGGACCTGCTCCGCGAGATGCAGGAGGAACTCGCCCGGGGTGCGGCCGATCCCGCGCTCGATCCGGAGGACCGGGCGACGGATGCCGTCGTCGCCCTCCTGCCCGATGCGATGAACGCCCTGCGCGGGAACGACCCGGCGCTGCTCCACTCGGTCCTCGGTCGGCTGGCCGAGGTCGCCGACATACTGCCGGAAGGGCACCGGCTGGCCCCTGTGCTGACCTTCCTACGGGCGGCCTACCTCGGCGTCGCGGACCGGATCGGCGGGAACCGCCAGGACGCCGAACTCGGCGCACGCCTGCTCGAAGCCGTCGAGGAGAGGTTCACGGAGGGCGGCGTCTCGCCCGTCCTCACCCCCATCGTCCGCTTGCTGTCCCTCGAATCCCGGTTCAGCCGGGCGGAGCAGGCAGCGGATCCGGCCGCGCTGGACGGGGTCATCGACGAGCTGCTGAGCTTGCGGGAGAGCGTGGCGACGGACCCGGACCTCCACTACCTGACCGTCGTGGAGCTGGCCCTCGCCCAGCTGGCGCGCGGCGACCTGCTGGGCGACGCCGAGGAACGACACCGGGCGCTGGCGCTCCTCGAGGAGGCCGAGCGGCAGGCCGGCAACCTGCACCCGGTCCTGCAGGAGGCGGCGGCGCAGCTGGCCGGCGTCCGGAAGCTCGGCCGGGGGCCGGACGAAGACCCCGCGCTGATCGACGAGGTGCTGTCCGTCCCGCGCCCCAGGGCGACCGGCGCCGGTGATTGGGAGCTCCAGCAGGCCACCGCCCGGCTCGCCCGGCACACCCGCACCGGCGACCGCGCCGACCTCGACGCCGCCATCGCCGCGCTCGAAGGGCTCCGCGAACGCACCCGGGAGGGCCGGGGCACCACCATCGCGGTGGAGACCTACTGGCGCCTCGCGGAGGCCTACGCCGACCGCGCCGACCTCACGGAGGACCCGGAGGACCAGCGGGCCGCCGTCGCCAGCGCCGTGGAGTCGCTGCGCGCGCACAGCGCCGACGTCCTCCTGGAGGCCGGCGCCGAGGACGGCCTGCTCGCCGCCCGCCGGGCCAGCGAGCGGGGTCTGCTGGTCGCCCGCTGGGCGGCGGTGTCCGATCTCCTGCCGGAGGCGGTCGAGGCCCTGGAGCTCGGCCGGGCGATGGTGCTCCAGGCCGCCGCGGACACTGCCGACCTGCCCGAGCGGCTCGCGGCCCGCGGCGCCCAGGAGCTCGCGGAGGCCTGGCGGGCGGCCGCCGCCGGGGCTCCGGCCGGAGCCGGGCTCCCCAGCGACCTGCGCCGCCGCGCGCTGGAGGCCCTGGGCTACCGCCAGGGGGTGTCCGGCACCCCGACCCTCGACGAGCTCTGCGCCGCGCTCGACACCGCCGACACCGACCTGCTGGTCTACCTGGTGCCCGGCGACGGGGAGCAGCCGGGGCTGGGGATCGTGCTCGGGCCGGCCTTCGGTGTGCAGGCGTTCCTGGCCCCCGCCCTGTCCGATGCGCAGAGCGGCCCGCTGCACGCGTACCTGGACGCGGCGGCGGCCCGCTCCGGGCAGCAGGACGCCGAAGCCGACCGCGCCTGGCAGGAGGCCCTCGCCGGCCTGTGCGACTGGGCCTGGCTCGGGGTGATGGGCCCGCTCCACGAGCTGGGCACGACGCTCCGGGCGGCCGACCCCGCCGACCCCGCCCCGCCCCGGGTCGTGCTGGTGCCGTGCGGCAGGCTGGGCGTGGTGCCCTGGCACGCCGCCCGGGTGTACGAGGGGGGCAGGTACCGCTACGCGTGCGAGCGGCTCCTGCTGAGCTACGCCGCCTCCGGGCGCCAGCTGCTCCGCGCGGTGGAGCGCCGCCCGATCCCGGTCGAATCCGCCCCGGTACTGCTCGCCGACCCCCGGCTCGACCTGCTCCACGCGGAGCGCGAGGTGGCCGCCCTGCACGCCGACTGCTACCCGAACGCCCGGCTGTTCGGCGAGTACTACGACCCGCCGGCCCCACCCAGCGCTGCCGGTACTCCGGCCGAAGTCCTGGCGCTGCTGACGACCGGCCAGAAGGCGGTCTCCCTCCTGCACGTGGCCTCGCACGGGTCGGCCGGGCCGCGCCCGACCGAGTCGGCACTCGTCCTGGCGCGCCCGGTCGGCACCGCCCCGGGACCGACCGTGGCCTCCGCACCGGACGCCGGGCTGCTGACGGTGGCGCAGCTCCTCGACGGCGAGGGCCTCACGGCCCGGCCCGCCGGGCCGCTCGTGGTGCTGAGCGCCTGCGAGACCGACCTGAGCACCCGTGACCACGACGAGGCACTGACCCTGACCACGGCCTTCCTGGCCCGGGGCGCCCGGAACGTGGTGGGGTCGCGGTGGACCACCGCCGACGGCGCCTCGGCGGTGATGATGGCGGTCTTCCACCACCACCTGACGGTGGCCCGGCTCGATCCGGCCCATGCCCTCCAGGCGACCCAGCGCTGGATGCTGGACCCGAAGCGCCGGCTGCCCACCGAGGTGCGCGGCCTGCCCGCGTCCTACGGGCAACTGCCGGGCCTGCACCGGCCGGAGGTCTGGGCCGCCTTCATCCACCAGGGCCACCCGGGCCCGGCGCCGGTCAGTCTCCTGTCACCCCCAGACTGAACCGCAGCTTGGGCTTCGCCACCGCCCCGAGCCGCTCGTAGAACCGCACCGCCCCCTCGTTCCACTCCGGCGTCTGCCACTGCACCTCACCGAAGCCGAGCGCCCGGGCCTCGGCCACCACCGCCTCGACCAGCCGCGCCCCGACACCCCCGCCGCGCACGCCCGCGCGGACGTACAGGCAGTCCAGGTGCAGGTACTCCCGCCCCTCCCAGGTGGAGAGCTCCGGCGCGCAGCTCGCGTACCCGACCAGCCCGCCGTCCAGCTCGGCCACCAGCACCCGCAGCCGGGCCGGCCCCGGCCCGAACAGCAGCCCGTGCAGCCGCTCCGCGAGGTCTGCGGCGGGCGCGCCGGCCCGCTCGTACGCCGCGTGCTCGGCCGCCAGCACGGCCACCGCCGCCAACTCCTCGGGCCGCACCGGCCGTACCGACACCGCCCCACCGTCCTGAATGATCATCACCCCATCATGCCGCGCCGCCGCTCTGCGCTGTGATCGCCCCTGTGATCCGCCTCTCACCGAACCGGACCCCCCCCCACCAGCGGGTTCCGGCTAGCGTCGGGGCATGCCTGCCAAGATCACCGTTGCCGAGCGCGAGCGCCTCCGGGCGGCCTTCGCGGACCCGGGCGAATTCGCCACCTCGCCGCTCTACCGGGCGCTCTGCCAGGTGGTGGCCACGGACGACGCGCTGCTGGAGCTGGCCGGCCGGGGGCGCCCGGGCCAGTACCCGACCTTCCTCTTCCTCGGCGCCGTGCACCAGCTGCTGCTGGAGGGCACCGAGCACCCGCTCGCCGGCTACTTCCCCTCGGTCACCACGGACCCGGCGCCGGCCGCCGAGGCCGGGCCGGCCCTCCGGGACTTCTGCGCCGTGCACGAGGGCCGCCTCGCCGAGCTGATCTCCACCCGGCTCGTGCAGACCAACCAGGTGCAGCGCGCGCTGGGCCTGCGGATCGGCCTGGCCACCGTCGCGGAGCGCACCGCGCAGCCGGTGCACCTGATCGAGGTCGGCACCAGCGCCGGGCTCAACCTGCGCTTCGACCGCTACGGCTACCACCTGGGCGGCCGCAGCTACGGCGACCCGGGCTCGCCCGTCCAGCTCCGCGCCGAGCTGCACGGCACCGGCAAGCTCCCCGACCTGGACGCCCTCCCGGCACTGGCGAGCGTGCTCGGCGTGGACCTGGCCCCCGTCGACCTGACCGACCCGGCGGCCCGGGCCTGGCTGCGGGCGCTGATCTGGCCCGAGCACCACGACCAGCGGGCGCTGCTCACCGCCTCCCTCGACCTGGTGGCCGCCGACCCGCCGGCGGTGCTGGCCGGCGACGCGATCGACCTGCTGCCCGGGCTGGCCCGCACCCTGCCGCCGGGCGAGCCCCGGGTGGTCTACCACTCGGCCACCCGGATGCACGTGCCGGAGGCGCGGCTGGCCGCCTTCGACGCCGCGATCGCCGCGCTCGGCGAGACCGGCCCGCTCTGGTGGCTCCAGGTGGAGGACGCCCCCGACCCGGACCCGCGCCCTGCGCCGGTCCTGCGCCACGGCGCCGCCCTCCGCCTGCGCACCCCCGAGGGCACGGCCGAGACCCTCGCCGTGGTCGAGGGCCACCTCCGCTGGGTCGAGACAATCAGCTGACGCCCCCGCGCGCCCGCACCGCCGGGCGCGCCCCGCACCACCGCGAAGGAGCACGACCATGCAGGACACCCGGGTGGACGAGTACCTGGCCCGGATCGGCGCCGCCCGCCCGGCCCGCCCCGACCTCGACGGGCTGCGCCGGCTCCAGGAGGCGCACCTGCTGGCCGTCCCGTTCGAGAACCTGAGCATCCACCTGGGCGAGCCCGTCTCCCTGGACGAGGACGCGCTGCTCGCCAAGATCGTCGACCGCCGCCGGGGCGGGTTCTGCTACGAGCTCAACGGCGCCTTCGCCGCCCTGCTCACCGCCCTCGGCTACCGGGTCGACCTGCTCAGCGCCCGGGTGTTCGGCGCGGCCGGGCTCACCACGCCCTTCGACCACCTCGCCCTGCGGGTCCAGCTCGACGGGCCCTGGCTGGTCGACGTCGGCTTCGGCCGCTTCGCCCGGCAGCCGCTGCGCCTGGACACCCGCGAACCCCAGCCCGACCCGGCCGGCACCTTCACCGTCGAGGCGACCCCCGAGGGCGACCTGGACGTGACCATGGCCGGCGAGGCCCAGTACCGGCTCGACCAACGCCCTTACGCCCTCACCGACTTCGCCCCCACCTGCTGGTACCAGACCACCTCGCCGGCCTCGCACTTCACCGTCTCCTCCACCTGCTCCCGCCCCACCCCCGCCGGCGGCCGCGTCACCCTGGCCGGCACCCGCCTGATCACCACCACCCCGGACGGCACCCGCACCGAAGCCGACCTCACTCCCGCCGAGGCCCTCACCGCCTACCGCGACCACTTCGGCATCACCCTCGACCGCCTGCCCGGCCTGCCCGGCCGGCCCTGAGCGCCTCCCCGCTCAGCCGAGCTGGCCGGCGGGGCGCACCACGAGGTGGCTGAGGTCCACGCCCTCGGGCTGGTTGACGGCGTAGAGGATCGTCGCGGCGACCTGCTCGGGGGTCAGGGTCTGGGCCGGGTCGGGGCAGCCGCCGCGCTCGTCCCAGAACGGGGTGTCCACCACGCCCGGGGCGACCAGGGTCACGCCGATGCCGTCCTTGGCCACCAGCAGGCGGACGTTCTCGACCAGGGCGTGCGCGGCCCACTTGGTGACCGAGTACATGTTGCCGGGCGTGTTCCTGATGCCCGCGATCGAACCGACCACCACGATCCGGCCCTTGGACCGGCGCAGGTGCGGCAGCGTCTGCTGCACCAGCAGGGCCGGGCCGAGCACGTTGGTGAGCACCATGGCGCGCATGGCCTCGGCCTCGTGGTCCTCCAGGGTGCCGGGCAGGGAGAACCCGGCGTTGGCGATCACCGTGTCCAACCGGCCCCAGGAGTCGACGACCCGGCCCACGGCGGCGGCGACGTGGTGCTCGTCGGCGGCGTCCCCGCCGATGGTCAGCAGCCGCTCCCCCGCACCGGCGGAGGCCGCGAAGGCGGCCAGCCGGTCGGCGTCGCGGCCGGTGACCGCCACCCGGTGCCCCTGCTCGAGCAGGCCGCGGGCGGTGGCCGCCCCGATGCCGCTCGAACCGCCGGTGATCAATGTGACAGGTCCCATGGGATGCCCCTCCGCACCGATGGCGGCACCGGCGCCCCGCCGGACCTCCGGCCCCGGTGACCGTGCGCCGCCAGTGATCAACTTCTGTCGCGGGCCGAGATGCTACTCCCCCGACGGACGCGTGCGGTCCACGGCTCACCGTGCCGGACCGGCCCGGCAGGGTCCGGAGGCGACCGATGGGGTGTGCGCGATGCCGCTCGAAGGCGAGTACCAGCCGAGTCCGATGCAGTGGATCCGCGAGCAGGTCGAGCTGTACGAGAGCTCGGGCGGCACACAGGGCACCACGCTCCGGGACACCGGGCTGCCGGTGGTGATGGTCACCGTGCGCGGCGCGCGCAGCGGCCGGCTGCACAAGGTCCCGCTGATGCGGGTAGAGCACGGGGGCTGCTACGCGGCGGTGGCCTCGAAGGGCGGCTTCCCGCGCCACCCGGACTGGTACTTCAACCTCCGGGCCCACCCGGAGGTGGACCTCCAGGACGGCCCCGCGCTCCGGGCCATGACCGCCCGCGAGCTGGCCGGCGAGGAGCGGGCCCGGTGGTGGGAGCGGGCGGTGGCCGCCTACCCGCCGTACGCCGAGTACCAGGCGAAGACGGCCCGGGTGATCCCGGTCTTCCTGCTGGAACCCGAGCGCTGAGTACTCCGGATCCCCGAGGGCTTGGAACTTCTCACAGAATGATCGAGGACGCTGCCGGGTGGAGGACTTGGGGTCAGAAGAGGTCCGCCAGCCGCTTGCCGATGTCCCATGCCTCGTCGACGGTGCAGGCAGCCAGATCAGTGGCTTGTTCCGCGGCGGCTTCGGCGAGCTGGGTTGTGGCGTAGAAGTTGACGCGGTTGCAGAAGACCTCGCGGATGTCGGCGCCGGTAGCCGGGGCGATGGTGACGGCGGCGGTGGCGGGAGCCGGGCCGCGGACGCCGTCCGGCGTGACGGTGAGGGTGCCAGGCCGAGGAAGGCTTCGTGGATGTCGTCGCGGATCTCCCAGCGGATACGCAGGCGGCGGAACCAGTGCAGATGGGCAAAGGCTCGCTCGACAACCCAACGTTGAGTGCCCAGTCCAGAGCCGTGCTTCGTGCCGCGTCTGGCGATCACTGGCTTCACGCCGAGGGCACGGACGAGGCGTCGGTACTTGTCGTGGCCGTAGCCACGGTCACCGAGCACCACGTCGGGCCGGTGCCGGGGCCGCCCTCGCTCGCCTCGCACCGGCGGAACCCCGTCAAGCAGCGGGATGAGCTGGGTGACATCGCTACGGTTGCCGCCGGTCAGCGTGACCGCGAGCGGGATACCGGTGGCATCAGTGATCAAATGATGCTTACTGCCTGCCCTGCCCCGGTCCACAGGGCTTCGTCCCGCTTTGGAGCCCCCTTTAACGCCCGGATGCGGGAGCCGTCGACCGCCACCCGGGGGAAGTCCGGCGCACCCGCACTGCGGAGCCTGGCCAGCAGGACCGCGTGGAGCCGGGGGCCACACACCGGCCTCGCTCCATTCGGCCAGGCGACGCCAGCACGTCATCCCGGAGCCGAAGCCGAGCTCCTGCAGCAGCGGCTCGACCACCGCTCACGGGCGTTCGTCCCAGTGGCGAGTCGCCCATGCCTGCCGGATCAGACTACGCACAGTGATGATTATGTCGGCGCGGTCGGAGAATGCCTCGATGACGGCGGCGTGCCGCTCGTAGCGGCGAGCGAGAAGACTGCTCCGGCAACCAGGATTACGAGGTGTGCTCGTAATCCTGAAGAAGAGAATCCTCGGTGGACGATGTCCGCAGCTGATCCGGCAGATGCTCAAGGCCGAGTATGCGGAGGACCGGCGGGCGAACGCCACGCTCAGCGGTGCACCACAGGGAGGCCTGGCCTCTATCTGGCCCACCGCGCTCACTGCTTCCTGACGGACCGCCCTCCCGCCCTGCCCGTCCTCAGTTGACCTCCCGCACTCTCGCAGCAGTCCGCTCGGCGAGCTCGCGGATGCCGTTCGCGGCGTTCTCCGAGAGCTCGCCGAGTATGGCGTCGGCGGCCGTGAGGAGGACACGAGCTTCCTCGGGGCGGCCCGCGGCGGCCAAGGCGAGGGTGAGCCGGTAATGCTCCTCGGCGATGAAGCGGCCGAGGTTGACCTGCTGCCAGCAGCGCAGTGAGCCGTCGCCCGGGGCGGCCAGGGCGTCACGCACGGCGGCCAGGCTGTCCGCCGCCTGCGACAACCGGCCCGCCTCCCGCTCCAGGCGGGCCAAGGTGCGCCGAGCCGAGGCCTGGTCCCATGCCGTCTCCTGGAGGGCTGCGTACAGGTGCTGGGCACGCAGCGCCTGGGGAAGATCGCCGAGCTCCTCGAAGTCCCGGGCGAGCCCGCTCAGCGGAGCCGTCGTCAGGGTGCGGGGCGCCTCGGGGCGGCGGAGTCTGCTCTGGTCCAGGAAGATGTCGTCGAGTTCGCGGATCAGCGCCACCCGCGCGAGGTCCGTCATCCCCTGATCCCGCGCCAGGTCGGTCCATGTGGAGACCGGCTCGCCCATCGGGTCCGTCCCGAACATCGACTCGTCGAGCGCCCGCGCCCACTGTTTCAAGTCGTCCGCGCTCGCACCCGGTTCCGGTATACCGCCCAGGCCGCACGCCGTATCGAAGTCCGTCTCCCGGACCTCAAGCAGCAGCGGCAGATCTGCGGTGTCCCCGCGCAGCCCCACCAGCACGGCCGCGAGCCGCAGTTCGTCCGTCATCGATGACCGTGTCTCGTGCCGCAGCAGATGCCGAAGCAGCTCCAGATCTCCCTCAGCGCGGTCGAACTGCGCGGCCCGCAGGGTGATCCGGCGCCGCACCGGGTCCTCGGCGACTTCACGCCATGCCGTGCGGTCGCCCTCCCGCAGCCGGGCGAGATCGGCGCGGCCCGCCGCGAGCACTGGCTCCCACAGCGGGGGACCGGCCGGGCCTATCCGGTCGTACGCGCACCCCTCATCCGCGTTGAGCAGTACGAATTCAGGCTCGGTGCGCAGCAGCGCGGCACGCAGCCTGCCCACCAGCTCGACCGGGGAGCGTTTCGGGAAGCCCAGCGCCGCACGGAGCTCGGCACGCTCCTCGTCGATTCCGTAGTACTCACGGATCTCGTCCTCGGTCTCCGCGACGCACGCCAGGATCTTCTCCTCACCGTCGTCTGGCGACAGACGTGTGTAGCCGCGCCAGCCGGGCAAGCCGATCACGAGCTCCAGGGCCTCGTCGACGCTCGAGCCGATGATCCCCGCAGCACCCTCGGAGTCGGCGTAGAGCACCGAGCCGTCCGCGCACACGAAGTACGTACCGCCGGTATCGTCCCCGGCTACCGTCTCCAGCGACCCGCCCGAGGCGAGGCGGACCTCCTCGACATGGCCGTGGGCGGCACGGTCCAGGTCGAAGTCGAAGGGGAAGGCGGCCAGTTCGGCCAGGCGGCGGTCCTGCCGCAGCAGCCATAGCGCGTGATCGGTCATGTCACAGAACGTAACACCGTCCACCGACAGTGATAGTCGTAACCGGGTCTCCGGTGGTTGTGGCTCTGCCACTGACTGATGCCCTGCTGGGCTGTCCTCCGGTTGTTCTGTCCAGCTGCCGGGCCCCGCTTTTCAACGGCCCTGGCCGGGTGGAGCATGACCTCACAGCGGCGGTCGCCTTCGTCACCGCCCACGGCACCGTGGCCGCGATCGGGGTGGAAGGCACCTCCTCCTACGGCTCGGGCTTCACCCGCACCGCCCGCCAAGCCGGACTGGCGGTGGTCGAGGTAGACCGACCGGACTGGGCCGAACGCCGTCGGGGCGGCAAGTCCGACCCCATCGACGCCTACGCCGCCGCCCGGGCCGCCCTTTCCGGCCGGGCCTCCAGCGCCCAAGGACGACACGATCACCGGCATCCGGGCCCTCGGCGCCCCCGAGGACATCCGCGCGAAGCACAGCACTCTGCGGGGCGACAAACGCACTGAGGCCCTCGCCCGCCTGGGCCCCGCCCGCAATGGCGTCCGCATCGCGGTGCTGACCGCGCTCAAGACCCTCGCCAAACGCGTCCAGGCCCTCACCGCCGCACCGCCGCCCTTGACTCCCTGGTCACAGAGCTCAACCCCGGCCTGCGCGCCGCCTACGGCGTCGGCCTCGACTCCGCCGCCCAGCTGCTGATCACCGCGGGCGGTAACCCCGACAGGCTTAGAACCGAGGCGTCCTTCGCGGCCCTGTGCGGCGTCGCCCCCGTCCCCGCCTCCAGCGGCAGGACCAACCCGCCACCGCCTGTCCCGCGGCGGCGACCGCGCCGCCAACGCCGCCCTCTACCGGATAGCCCTGTGCCGGATGTCCAGCGACCCGCGCACCCGCGACTACGTCGCCCGCCAGACCGCGGCCGGCCGAACGAAGAAGGAGATCATCCGCCTCCTCAAGCGCGCCCTCGTCCGGGAGATCTTCCGCTGCCCCACCACGACCGTCGCGGTCCCCGAGACCGCCGACCTCCGCCCGGCACGCCAGGCCAAGAACATCCCCCTCGCCGCCGTCGCCCACCACTTCGGCGTCTGGCCCGCCGTCATCTCCACATCGAACGCGGCACCCGCCGCGACGACTTCCTCGCAGCCGCCTACTGCGACTGGCTCACCGCCGATCAACGACCGGCCTCGACATAACCGGGATGCCTCACCGGCGGAGATTGAGGAACACTCTGCGGGTGATCGTGATGCAGCCCGTCCTCGAGATTTACGCCCCTGACGACTTCGCACTCTGGCCCATCGCCGCGTGGAAGCAGTTCGAGTACCTGACACTCAACGGTGGACTCGACCCCGCCGAGGTCGGGATCGCGATCATGCGCATCGCCGAGTGCAACGACCTTGACCCCGATCCCGAGAACGGCGATGACCGGCCGCCCCGGCCGGCTGACCCGACCGAGTCTTTCCTCCACGGACTGCTGACCTTCGACAGCCTTCACGTCACCGGTGGCCTGCGAGTTACCGACACCTCCACCGGGATCACCTTCGTGCCCGGCTGCTGCGGCGGGCTGGAAGACTGGCGCGACTGGTCCTCGGTCACCGACGGCACCGGCGCTGCCATGTTCGGCCACGACCCCGTCGCTCTTGCCGAGCGCGACGGCGACACCGTTCGGCTGACCGTCGACCGCGAGCAGAGCGACAGCCCCGTGATCGAGTTGCCCGTCACCGACCTCCGCCACCTGCTGGCCGGCGCAGAACGCGACCTCACCGACTTCCACCAACTCGCAGCCAACTGGATCGCCCAACACCTCCCCGATCAGGCCATCCGCGTCACCGCCGCCGTCGCCGACGCTCTTGATCTGCTCCAACCGAACGCGGCGCCATAGAAACCACCCAAGCAACGGCCCACATCAACGCTTACACGCCCTGTCGCCCATGCCTGTCGAATCGGGCTACGTACGGTGATGATCGTGTCGGCGGGGTCGAAGAAGGCGTCGATGACGGTGGTACGCCACTCGTAGCAGCGGGCGGGCCGGTAGAAGGCGTTCTGACAGGCGCGGGTGCGTTCGACATGCCAACGCTGACTGGCCTGGACGGGCGCATTCTCCCCCTTGTGCGCGACGCGTCCGCGCAGGCAGCGTTCGCTGAGTAGCGCGCGGGTCTTGTCCGACTCGTAGCCGGCGTCCAGGTGCACGGTGATGTCGTCGGGCACCGGCCCCAGGTCCTCCAGACGGTCCAGGGTCGGAGCGAGCAACGGGGAGTCGTGGCGGTTTGCACCGGCCAGGACACGGCCCAGTGGAATGCCGTACCCGTCCGTCGTGCCCGAGCGTTTGCGCCCTGTCTGCCGCGGTCGACCGGTGGGCGGCCGGCGACCTCGCCGCGTCCGGGCGCCTTGGTGATGGAGCCGTCCACGGCGATCTGATCGAGGACCAGGCCGACGGTCCGGTCGTAGGAGTCCAGTGCGATCTGCTTGAGCCGGGCGAACACGCCGAGTCGGATCCACTCGTCGCGGCGGCTGCGGATCGTGGCAGCCGAGTGGGTCATGGCGGCGATCGCCTCGCAGCAGGACCACGAATTGATCCCAGAGCGGTTCGATGAGCCACGATGGAAGCGCGGGCACAGGCCTCCCAGGCGATCGCCTATCAGCGCGACCTTCTTAGGTAGGGCTTATCCCGGCGGGGTAGGTGGCAGGGTGGAGGTGAGTGACCATGAGGCACTTCCACCAGTTCGGCCCCCACCACGGCGGGTGGGTCTGGGTGCTGTCGGGCATCACGATGATCCTGCTCTGCCTGGTGCTGATCGCGGTGCTGGTCACCCTGGTGCGGTTCTGGTCGCACCGGTCCGGCCCCGGCGCCCAGCGCCACTACGGCGGCCCCAAGGGCCCCGGCTGGCAGCAGCACGGCGGCGCACCCGGCTGGCAGCCGCCCGCCCCGCCGCAGGACCCGGCCAAGCTGCTCGCGGACCGGCTCGCCCGGGGCGAGATCGACCCGGAGGACTACCGTCAGCGGCTCGCCGCGCTCCAGCAACCGCCGCCGGGCGCACCGGGTCTGTAAGGGATCTCTCACCGTCACCCGACCGAGGGAGGTTTGGCCCGCCGCCCGGCACTCCGTACAGTTCGTCTTTGGACCAGGCACGGTGCCGGGCCGGGCGGACGAGGAAGCAGCGGCGAGCATGACGGAGCAGGACACCCCGGAGGAGCAGATCGAGTATGGCCCGGGCATCGCGCCCGAGCGGCTGGAGCTCTTCCTCGCCGTGCTCGCCGAGCTGGACGAGCTGGAGGTCGACCACCCGGACGCGATCAAGGTCCGGATGGCCGTGGGCGGCATCTTCCGCACGCTCAAGCAGCGCCGCCGCCAGGAGACCCGGGCCCGCAAGACGGCCAACGACCGCGCCGTCACGGCGGCCACGGCCACCGGCGCCCCCGGCCGGATCGACGACGAGACCGCCGGGGCCTTCGGCCTGACCACCGCCACCACCACCGAGATCGCCGGGATCCTGGAGCGGCCCCGCTCCTGCTACACCTGCAAGACCCGGTACGTGCAGGTGGACGCGTTCTACCACCAGCTCTGCCCGCCCTGCGCCAAGGACAACCGCAGCCGCCGGGACGCCTCCGTCGACCTCAGCGGACGCCGCGCGCTGCTCACCGGCGGCCGGGCCAAGATCGGGATGTACATCGCGCTGCGGCTGCTGCGCGACGGCGCCCACACCACCATCACCACCCGCTTCCCCAAGGACGCGATCCGCCGCTTCAAGGCGATGCCGGACAGCGCCGAGTGGCTGCACCGCCTGAAGATCGTCGGCATCGACCTGCGCGACCCGGCCCAGGTGGTCGCGCTCGCCGACTCGGTGGCCGCCGAGGGCCCGCTGGACATCCTGATCAACAACGCCGCGCAGACCGTGCGCCGCTCGCCGCAGGCGTACAGCGAGCTGGTCGCGGGCGAGCAGGCCCCGCTGCCCGCCGGCGAGCTGCCCGTCTCCGAGGTGTTCGGCAGCTTCGGCAGCGGCAGCGTCGAGCGCCCGATGCTGCCCGGCCAGCCCTCCGGCACCCACGAGGCGCTGACCGCCGACGACGTGGCCGCGCTCGCCCTGGTCACCGGCTCGGCCTCGCCGGCCCGGATCGAGGCCGGCACCGCGATCGACGCCGGCGGCCTGGTGCCCGACCTGCACGACACCAACACCTGGGTGCAGACCGTCGGCGAGGTCGACCCGGTCGAGCTGCTGGAGGTGCAGCTCTGCAACGTCACCGCGCCGTTCGTGCTGGTCAGCCGCCTGCGCCCGGCGATGGCGGCCTCCACGGCCCGCCGCAAGTACGTGGTGAACGTCTCCGCGATGGAGGGCCAGTTCAGCCGCGCGTACAAGGGCGCCGGCCACCCGCACACCAACATGGCCAAGGCCGCGCTCAACATGCTCACCCGCACCTCCGCCAAGGAGATGCTGGAGACCGACGGCATCCTGATGACCGCCGTGGACACCGGCTGGATCACCGACGAGCGCCCGCACCCGGACAAGATGCGCCTCGCCGAGGAGGGCTTCCACGCCCCGCTCGACCTGGTCGACGGCGCGGCCCGGGTCTACGACCCGATCGTCCAGGGCGAGTTGGGCCAGGACCTCTACGGCTGCTTCCTCAAGGACTTCAAGCCCTCCGCCTGGTAGCACCCCCGCTGGTAGCCTCCGGTGACAACTGCTCACCGGAGGCCACCACCATGCCCACTCCCCCGCTGCTCGGTGCCGGCGTGATCGTCCCGAGCACCGACGGCCGCCACGTCCTGATCGGCCGTCGCACCACCCCCGGCGAGCCACCCACCTGGAGCCTGCCCGGCGGCAAGGTCGACCAGCCCGGCGAGTCCTTCGAGCAGGCCGCCGCCCGCGAGCTGGCCGAGGAGACCGGCCTCCAGCTGCCCGCCGCGGAGATGCGGGTGCTCGCCATGCTGCTCGACCACGCCACCGGCCGGGCCCGGCTCACCGCCGCCGTGCTGGCCCCGCCCTCCGACGCCCCGGCGCGGAATCTGGAGCCGCACAACTGCGCGGGGTGGGAGCGCGTCCCGGTCGGCGCGCTGCCCACCCCGATGTTCCTGCCCTCCGGCCTGGTGCTGGCCTCCTGGCTCCCGTCCGCGCCCTTCCCGCTGGACGGCGCCTTCCGCTACCCGGTCGGCTGAGCCCGACCCGCCGACCCCCCGGCCGAGCCCGACCAGCCGACCCCGCCCGGCCGAGCCCGACCCGCTGCCGTTGCCCGGCCGAGCCCGGTCACTCCACCCGCGCCGCGCTCCGCCCCGCCGCGAACCGGCCCGCCGCCGTGATGCTCGCCGCAGCCGCCGCCCCGGCCTGCTCGTCCGGCTGCTCCCCCTCCGCGCCCCGGCGGTGGCGCAGCGTCAGTTCACGGCTGCCGTCGGGCCGGGCGGTGAGCCGGTAGTCCCAGCCCTGTGCGGCCCCGGGCGGGCTGGCCAGCCGGACGGAGACCTCGCTCGGCCGGGTGCCCGGCTTCAGGTAGGTGGACTGCTCGATGCTGCGGATCTGCTCCACCGGATCGCCGCTCAGCTCGAACTCCTGCCGCAGCGGCAGGTCCGGGCCCTCGCCGGAGACGGTCAAGTGGAGCCGCCCGACCGTGGGCAGCCCGCTCTGGAGCAGTGGGCGGGCCGCGTCCGAGGCAGTGGCCATCGCGGCGGTGACCAGCTCGTTGGCCGGGCCGTGGTCCGTCCACGCCTCGCGGTGCACCTGGTACGGATCCTGCTCGGGCCAGCCGTCCTGCGCCCCGGCGACCAGGTCGTCCAGGGTGACCGGCCCCTCGGCCTGCTTGCGCTCCACGTAGTCGAGCACCTGGCGCACCTCCTCGCCCTTGAGCGGGGTGCCCGCCGGCTTGCCGAGCAGGTCGCCCAGCAGGGCGGAGGTGGCGGTCGAGGAGCCGCCGGAGAGTTCGACCAGTCGGTGCGCCGCCTGGATGTGGGCCTCACCGGCCGCCGTCCCGGCGGTGAACCCGCTGCCGTAGGCCGCCCGGCCGACCCGGGCGGTGCCCATCAGCTGCTCGCGCTCGGCGGGCGTGGCGGTGGCCTGGTCGAACGGGTGGCCGCCCCCGCTCACCACCTGGTGGACGTCCTCCAGTAGCCCGGCCCCCTCGCCGGAGCGCAGCTCACCGCTGTGGTGGTCCTCGGTGAAGGCCAGGTAGTGGTCACCCGGCAGGTCCACCGCAGTGGTCTCGGACAGCGGGATGTCCACCGTGAAGGGCACCACGCCCTTCTCCTTGACCGGGTTGCGGTTGCCGTCGAAGAGGGTCACCTCCACCTCGGCGTGACCGCTGTAACGAGCCATCGGGGTGGGGTACTTGGCGTTGTTGACCACCTGGCCCGAATCGCCGTGCGTGCCGCCCTCGCGCCACAGCCGCTGGGTCCCGCCGGTGATCGCCGGGTTGTGGCTGGTGATCCCGGCGGTGACCCTGGCGCCGACCTGGCCCTGCGCCCCCGCGTTCTTCGAGACCAGTTCCGCATGGGTGGTCCCGGAGGAGGTGTTGTTGGACGGACTCAGCTCGACCGCCTTGTCGGTGTCCCCATGCTCCAGGGAGACGATCTTGACGCCGACCTCCACCCCCTTGCCGCCGGCCAGCGTCACCCGCTTGCTCGGGATGCTCGCCGCCACCTCCGAGCCCTGGGTCGCGGTGCCGAACAGCGCCGACAGGTGGCTGTGCGAGGTGACGGACCCGACCAGCGGCTGCATCTCCTCCCAGGTCTTCTTGCCGAAGTACTCCGGCCCCCGCAGCCGCACCAGGTCCTGGACCCCGCCGACGTCGCCGAGGTGGCGCAGCACGTCGGTGTCACGCAGCCCGGTGTCCCAGACCCGCTCCGGCGGCACCTGGACGCTGACCCGCTCGGGCGCCTCGGCCGGGAGGGTCCGCGGCGGCCGCTCCGGGCCCGCCGTCTCAGCGGAAGGCTTCGGCGCCTCGGCGGAGGGCTTCGACGGCACCGGCCGGGTCTCGCTCGTCTCGACGATGGTCTCGAAGCCGATCGCCGCGGTGCGCCGCTGGTGGACGGACGGGCCGACCAGGGGCCGCCGGGTGATCGTGAACTGCAGCTCCGCCTCGCCCCGGTAGGCGCTGCCGGGCACCTTGGCCTTGGTGGCGGAGCCGGCGCCGGTGCCGGTGTTCCGGACGTCCACGTGGTCGTGGCCCCGGCCACCGGTACCGGTCAGGCCGGCCGTCACCGACACGGGTGCGCCCGGCACGGGGACGGCTGCCGTCGCGCCGAAGACGCCCTGGTGGCTGTTGCCGGTGCCCTCGGTGTCCGCGAAGGACCGCTGGACGTCCGTGCCGGTGTTGAACTCGGTGGTACCCGAGTCGCCCAGGTGCTCCATCCGGTCGCGCAGCACCGCGCCGACCCTGACGGTGGTGCGCCCGTGCCGCACCACGATCTCGTCCCCGGCCGTCATGCCCTTCAGCCGGGACTGCAGCCGGTCCGGGGTGAGCTCCGCCTCCAGCTTGCGGTGGATGCCCGCCCAGTCGCTGCTGAACGGATTGCGCTCCGTCGGCGAAGGACCGGAGGTCCGGCGCGAGGCGGCGGGCTTCCACCCGGCCTCCACCTGGGAGAGCACGGACTCCCCCAGCGTCCGCCGCGGCCCGGGCGGGATCTCCGCCTTGCCGTCCGCCGTACCCTCGACCTTGCCGTGCCCAGCTTCCGGCAGCGCGTGGATGTCGGTGACGATCGCCGAGGAGTCCAGCCTGCGCCCCTCCACGAACCCCTTCGGCTGTGTCGTCGTAGTCCGCTCCACCGGCCCGCCGACCGGCTCTGCGTCGCGCATCGGCACGGCCACCCTGGCCACCGTGTCCACCTGCTGGGTGTGCGAGCCGTCGTCCACCCCCAGGCGCTTGAACGTGACCTTCACGTCGTACGCGGCGCCCACGTCGAAGATCACGGCCGGCTCCACGTGCTTGCCCCGGTTGGAGGCCGAGCCGACGGTCTCCACGCCGTTGGCGTAGGTGCGGTCGATCCGGTGGCTGTAGCCGCCCCCGACGGTGACGAACGGGGCCCGCACATTGAACCGGCCGCCGGCGTCGAGGCGCTCGCGCCGGTCCCGCACATTGCCCTGGCCCCGGGAGGAGCGGGTGCCGGACTCGAACTCGTACTTCTCCGCCGTGGAGTGGTAGGCGCTGTCCGTCACCCTGGCGGTGACGGTGACCTCGGCCTTCCAGGTGGTGCCGGAGACGGTCTCGGTGATCTTCCCGCCCCGGGTGAGCTGGGAGAGCTGGGCCTTGAGCGCGACCCGGTCGAAGGTGGCCCCGATCCGCTGGCGCACCTCCTCCGAGGGCTCGCCGTACTTGGACCGGACGGCGTCCTCCACCGTGGTGCGCACCTTGTCCGCGCCACTCAGGGTGTGCACCACGTACGAGGCGTTCAGCTCCTGCTGTTCCCGCATCCGGCGCGGCGCGGTGTGGGTGGCCGCCGGCCGGTCGAGCTCCACGGCCTCCCGGCCGGCCCCGTCCGGACGGCCGCCCGCTGCGGGCTCGGTCGACTCGGCCGACTCGGTCGGCGGCTTGAACGCGATCGCGCCGTCCTCGCCGACCGGCGCCTCGGTCTTGACGGTGTCCCGGGCGTCCAGGCCCACCTCGACATGCAGCGGCGCCGAGACCTCGGACTTGCCCTCCGGCTTCTCGCCGGGCCGTCCGAAGTGCACGTCCACGGCCAGGTGAGCACCGTAGATCACCTGCGGCGCGCTGTACTTTCCGTTGGCGTACACCCGGTCGGCCTGCCGACCCTGCCCGCCGACCCGTTCGCGCTGCTGGCCGGTGGTGACGGCACCCAGGTCGGCGCCGGGCGTGCCCTTGGCGACGGTGCCACTGAACTGGCCGGTCGCCGCCACGGTACGCGACTCCAGGCGGCGGTCCACGCTGAACGTGCTGGTCTCGCTCACCGTGTTGAGCTCGGCCTTGCCGTCCTCGCGGCGGAAGGTCATCGACTCGACCCGGGCCGTCGCCGTGACGACCAGGCTCTCCTTGCCGGGGACCTTCACCTCCAGCGGCTCACCCCGGGTCATCCCGGTCAGCCGGGCGGCCAGGTTCGGCTGGCTGAAGCCGCGCAGCACCTCACCCCGGACGGCGTCCCAGTCGTCGCCGAAACGTTCCCGCCCCTTGGCGTCCACGGCCGCCCGCAGCGCGGCGGTGGTCTCCACATCGCGCACCACGACGGTCTCACCCAGGCCGCCCCGGTCGTCGCCGCCGTGCCAGACCGAATCCGGCGGCCCGGCGACCTCCTGGGTCTTCGGCGGGGCGGTCCCCTCGGTCTCGACAGTCTTGGCGGTCTCGGTCGCCTTGCCCGCCTCGGCGGTCTCGGTCGCCTTGCCCGCCTCGGCGGCCTTCGGGGTGGTGTCGGCGCGGTCCACCAGCAGCCGGACGTCGGCCGTGCCCGCCGGGTGCGTGTCGGGCTTGCCGTTGAACGAGAGCTCGAAGTGCACCGGGCCCTCGTACCGGACGCCGGGCACCTTGGACTTGCTGGTCAGCTGAGCCGCCCGGCTGTCGCCCGAGATCTCGATCCGGTCCCGGCCGAGCCGCCCGGCGCCGCCGACGCCCATCGAGACGGGAGCCGGGCGCAGGGTGTTCGCCAGGCCGAGCTGCCCCGCGTTTCCACGGCTCTTCGCGCTGCTGCGCACCTGCTGGACGCTGGTGCCGATGTTGAACTCGGTCTCCTTGGTGGTGCCGGTCTGGTGCAGGTCGCCGACCCGCGCACTGATCTCGACCGAGCCGATGGTCCGGCCGCGCCGGTCGGTCAGCGCGACCGTGACCGGCTCACCGGCCGTCATGCTCTTCAAATCCCGCTGGAGCCGGGGGAAGTCCACCTCGGCGAGCACCTTCTCGCGCAGCGCGGGCCAGTCCTTGCCGAACTCCTTCCTGGCCGCCTCGTCCACGTGGTCGAGCAGCCCCTCCACCGGGCGGTGGCCCTCGGACCCGCCGTGCGGCGACAGGTCCAGCACGATCTCCTGCCCGCCGACCCGGCCGTCCCGCAGGCGCTGCGGGGGTGTCCGCAGCTCGCCGACCGCATCGCCCTCGGCCCGGACCGGGCGGGCCACGGTCATTCCGAGGTCCACCGTCTCGGTGTGCCCGCCGGAGCCGGTGCTCACCGGGGTGTGGTCGTGGCGCAGGTCGCCGAAGTCGAGCTCCAGCCGCATCGTCGACTTGAACACGTCGGCGGGCTCGGAGGTCTTCGACCGCGCCACCATGCCGCCGAGATCCAGGTTGACCTCGCCGTGCCCACGGTCGTGGTGGTAGGCCGCCAACTCCGCCGGCTCGGCGCCGGCCACCGTCTGCCGGGCCTGGATGCCGATGTTGGACTGCCACTGCACGTCGTGCTGGCTTCCGGTCGACACCGTCCGGTCGGCGCCGTTCTCGAACTCGATCTTCTCGGTACGCAGGTGCGTCGACTCGGTGAGCTCGCCACGCAGCTTGACGCTGCCACTCCAGCCGTTGCCCTCCAACTTGGCCGTCCACGTCTCGCCCCGGGAGAGGGCGCTGACCATCGGGCGCAGCGTCGCCGGGCCGAAGTGCGCGTCAGCGAAGGCCCGAGCAGCCGCCCGGTCCCCCGGCACGGCCCGTTCGAGGACGGCCAAGACCTTGTCCCGGACAGCCGTCTCGTGCTCGGTCAGCCCGACCACCAGGTCGGACCCCTCGATCCGCTTGGGCCCGGCGGGCGGCTTCGGCCCGCCCCCACCCTCACCCTCCGGCTTCGGCGTCTCGGGCGCGGGCGGCTTCGCCGGCTGCTCACTGCTCTCCGCCTCCGCCGGGTCCTTCGGTACAGTCGGCTCCGCGCCGGCCTTCTCTTCCGTGGTCTTCTTCTCGGTCGCCTTCTGCTGGGCGGGGTCGTTCGTGTGCTGGTGCGCGGCAGGGGTGGCCGGCGGGTGGGGGTCCTGCGGCGCGCGCGGGGGCGGCTCGCTGCCGTCGTAGTGGTTGCCCCGGTGGTAGACCGTCACCGGCCGCCCGTCCGCCGGACCGAAGACGGCCCGTGGCACCCCGTCATGCCCGAGCACCCGCAGCCGCAGGCCCAGCGCATGGGCTGCCGCCGCCGGCAGCATCTCACCCTCGGTGGTGAGCCAACGCCGCTCCCAGTCCCGGGCGGTCCGGAGCAGGGCGGCCCGCTCGCGCGCCGAGGGCGGCGGAGCGTTGTGGGTCAGGTGTTCGCCGACGATCTCCCGCAGGTCCCGGAGCGGGAGCCGCTCGTACCCCGGCCGGACATCCGCCGGGAGGTAGTCGAGCAGCTCGCTCCGGGTCAGGTCGCCCCGGGCCACCAGATTCCCTCGGTAGTTGGCCACCACCTCGGTGGGCCAGTGCTCCGGCGGCAGGTCACGGAAGTGGTCCTCGACCGCCGACTGCAACCGCCGCGCCGCGCCGGCGCCCCCCGTACCGCCGTGCCCCACCAGCTCGGGCGAGCTCACGGCGAGCGAGTGCAGCAGGCAGAGCCCGTCCCCCGCCACCGGCACCCGCCGCCCGGCAGGCGGGAAGTCGGTCTCGGTAACGGCCCGACGCGAGGGCTCCGGAACGTTCCCCTCCCCCTCCGGCGGCAGCCCCTCACCCGCCGGGTGCTCGACCGACTTCTCCGTACCGGCTTCACCTGGGATCTCCGAAGACGGCGGAGCACCATGCGTCGACCCCTCGACGTGCGACTCCTGCTGCTCCTGCCGGCCATGCTCCTGACCCGCCAGGTGCTCGGCCGACATCCCCCCGCCGCCCTCGCCCTTGCTCCCGCCCAGGGTCTCCGAGGACGGCGGAGCACCATGCGTCGACCCCTCGACGTGCGACTCCTGCTGCTCCTGCCGGCCATGCTCCTGACCCGCCAGGTGCACGGCCGACTTCTCCCCACCGCCCTCGCCCTTGCTCCCGCCCAGGGTCTCCGAGGACGGCGGAGCACCATGCGTGGATGCCTCTACGTGCGGTTCCTGCTGCCCGTGCTCCTGGCCCGCCGGCGGCAGACCTCCCTCCGCCTGGTACTCCGGCAGGTGACTCCCGGCGCCGTCCACCCCGTCCATGAACTCCCGGAAACCCTCGTACACCCGGTCATCCGCCGCAGCCTGCCGCTCGGGCTGCGGCACGGCGTCCTGCTTCGGCCTCTCCTGCCGAGTGGGCGAGGCGGACCGGTCGGTACGGCTCCGGACGGGACCCGGCCGGAGTGTGCCGGCGGGGCTGTCGGGCCGGGTGTTCCGAACCTCCGACGGCTTCGGCGTACTCGGTGTCGGCGAGGCGGGTCGGCTGCTGCTCCCGTGGCCGCCACCACCGCCCGCCACCGGGCCGGGCACGAAGCCGCCGCCCACCGGCGGGATCGCGGTCTGGTTCTGGGCACCGGACGCCAGCGCCGGGTCGGCTTCGCCCGGCACCGGGACAGCCTGCTCCGAGCCCGGACGGGGCTGGGTCTCAGCGCCGGAAACCCGGGCCCCACCGGCAAGGCTCGTGTTGTCCCCACCCCCGGACGGGTGAGCAACACCGCTGAGCACCCGACCCAGATCGGGCACCGTCGCCGCACCACTCCGCTGCAACGGGACGGCAGACGACTCCGTCCCGACCTCCTCAGCCCGCAACGTGTGCTGCTCGACCGGAGCTTCCGCCACCACCGCCCGCTGCTCGTGCGCGGGCGCCACCGGCTCGGTCACTGCCGCACGCTGCTGGGCCGGGGCCTCCGCGACCACCGCTTGCTGCTCGTGTACGGGCGCCACCGGCTCGGTTACCACCGCCTGCCGCTCGTGTACGGGCGCCACCGGCTCGGTCACCACAGCGCGCTGCTCGCCCGGTACCTCAGCCACCACGCCCTGCTCACGGACAGGGGCAGTCTCCGGCACCACCGCCCGCTGCTCACCCGGTACCTCAGCCACCGGGTTCTGCTCATGCGCCGGCGACTCCGCCACCACCGCCCGCTGCTCACCCGGCACCTCAGCCACCGGGCTCTGCTCGTGCATCGGGACGGACACCCCGGCGCCTTCGCGCTCGACGGGGTGCTCGACCAGCGGCGCACCGGCAGGCCCGGGCTGCTCGGCGAGCGGCTCGCGCAGGGGCTCCGCCTGCTGCGGCAGCTCCTCGCGGCCGACCTCCGACCGGATCGCGGGCTCCTCCGCCGCCCGGTGCTGGCTCGTCGCCGACGGTGCCGGCGAGAGATCGTCGCCGCCGCGCGCCAACGCAGGCTCGCCGACCTCCTGACGAGGCATCGGTTCCTGGAGCGTTGCCGTCGGCATCTCCTGGCGGGTCGCCACCGCCTCCTGGGCCGGCACCGCCGGCTCCTGTTCGACGCGCTGCGCCGACGGGCTGTCGCCCCGCGACTCCTGCGGGGCTGCCGCTTCGCGCAGCGTCGCCGGTTCCCGCTGCGCGACCTGCTCGCGTGCGGTCATCGGTTCTTGCTGCGCGACCTGCTCGCGTGCGGTCATCGGTTCGCCGGCAACGGACGACTGCTCCGGGCGGCCGACCGAGGCCACGTCGCGGAGCTGCGTCTCCGGGGTGACCGAGGACACGTCGTGAAGCTGCGCCTCGGGAGTGGCCGAAGCCGAACGGTCCGGCACGCCTTCCATCGACCGGTCCACCGAACGAGCCGACACCGCGCCCAACGACCGGTCCACCGAACGAGCCGACACCGCGCCCAACGACCGGTCCGGCGCACCCTCCATCGACCGATCCAGCGAACGAGCCGACACCGCGTCCACGGACGGGGTCCGGGCCGAGGCCGAAGCCGAGGGAGACCCGAACGGCACCAGTCCGTTCACCCGCGACTCGTCCGCACCGGCCCCCGGGCCATTCCCGGCTCCCTCGTCGCCGCTGCCGCTACCGAGAGAGCGACTGGCCGGCCCCTGGTAGGTGTTGTCCCCGGCGGAGCGGGTGGAGGTCGAGAAGGTCGGCGGGCCGTCGGGGCCGCTGCGGGTGCCGGCGCCGGCCGAGTCCAGGTGGGGGGCCTCGGCGAGCTTGGGGGCATCGGGGTGACCCTTGAGCGCGGCAGCACCGGCGTGCAGGCCGGCGCCGGCGCCGCCGGAGAGGCCGGAGCCGAGCAGGGAGTTGGGGTCGACCTTGCCGGTGGTGATGAGCTGGGTGGAGACATCGGCGCCGACGCCGACCACTGCGCCGGTGGCCATCTTCCCGGCGGTGGAGTTGAGCGCGCCCTCGGCGCCCAGCTTCTTGCCGGCCGCGCCGATGCCCTTGCCGATCAGGTGGGCGGAGGCGCCGCCCACCGCGCCACCCAGGGCGTTCTGGCCGACTTCCTTCATGTCGATGCTCTTGCGGTGGCCCTGGGCGAGCTCGATGCCCTGGGCGAGCAGGTTGATCGCGGCCATCTGGGCGGCCTGCTTGGCCGCCATCGTGATCATCTCCTTGAGCAGGGTCTTCAGGAGGGTGGAGACCACCGCCTTGCTGACCCCGATCATCGCCGGGACTTCGAGCAGCGAGGCACCGGCGGTGAACGGCGCCTCGGCCTCGGCGGTGGCGATCTCGAAGGCGAGGATGCCGAGTTGGGCGATGATCTGGATCTTCGCGGTCTCGGCGGAGTTGGCCATCTGCTCCAGCATGTCGCCCATGCCGTCGAGCGCGTTGATCGCGCCGGGCAGGTAGCCGGGGTCCTCCGGCGTGCCCTTGCCGGTGCTGTACTTGGCCCAGTACGTGGTGAGCGCCTGCGCCGCCGCGCCCCGCTGCCCGTCCAGCGCGCGCTTGATCGCGGCGTCGGAGCTCTGGGTGGCGTCCTTCAGCTCCGTCGCGGCCTTGCGGCAGTGGTCGGCCATCTCCCGGAGCTGGTCCTCGTCCGCCTCCGGCCAGCGGCAGCCGGCGAGCAGCAGGAGCACCCACTGGAGCGGCTCCGGGAGTTCCACGGCCATCTGTTCAGTGCCTTCCGCTCTGGGTGATCCGCGGGGTCATCGGGACGTGCACGGGGGCGTCCGGCATGGACGGCGGCGCGGGCAGCGGGGCGGCGCCGGTGTCGATGCCGTCGAGCTCGGCGACGACGTCCTGGTCCGCGCCCTGGTATCCCTCGGCCATCGCCTTGAGGCCGTCGGAGATGCCCTTGAGCGCGTCGGGCAGGCCCTTCAGCACGTCCAGGGTGTCCTTGCTGTACTTCAGGTAGCCCTTGTCGCCCTCGGCGAACTGCTTGCCCGACTCGTCGTTGCCCCAGGGGTTCTGCGCCTCCAGGGCGGGCAGGAACGCGCTCAGCGAGGTGTACACCGAACGGATCTGCTCGGAGGCGGCGAGCAGCGGTGACACCTCCGCCTGGTACTGCTCCGGTACGACCTGGAACCCGTCCTCGCTCATGGCACCCTCCGATTCGAGGAGGAGATTAGGGCGCTGACATGACCGCCACATGGCCGGTCGGAGGCCGCGCGGTGATGAGGACTTGACGACAACTCAGGAAGCCCGGGCCCGCAACGCAGAAGTCCCCGGGCTCCAGCGGGAGCCCGGGGACTTCGTCAACGCATCAGCGCATCAGCACATCACTGCGTCAGCGCGTTCAGGCCAGGGTGGCCAGCGCCTCGTTCAGCGTGGCGGACGGCCGCATGACGGCCGAGGCCTTCTCGACGTTCGGCTGGTAGTAGCCACCGATCTCGACCGGGGAGCCCTGGACGGCGATGAGCTCGGCGACGATCGTCTGCTCCTGCTCGGTCAGGGTCTTGGCGAGCGCGGTGAACGCCTCGGCCAGCTCGGCGTCGGCGGTCTGGGCGGCCAGCTCCTGGGCCCAGTACATGGCCAGGTAGAAGTGGCTGCCGCGGTTGTCGATGCCGCCGAGCTTGCGGCTGGGCGACTTGTCCTCGTTGAGGAAGGTGCCGGTGGCGCGGTCCAGCGTGTCGGCCAGCACCTGGGCGCGGGCGTTGCCGGTGGTGGTGGCCAGGTGCTCGAAGGAGGCGGCCAGCGCGAAGAACTCGCCCAGGCTGTCCCAGCGGAGGTAGTTCTCCTTGACCAGCTGCTGCACGTGCTTGGGGGCCGAGCCGCCCGCGCCCGTCTCGAAGAGGCCGCCGCCGTTCATCAGCGGGACGACCGAGAGCATCTTGGCGCTGGTGCCCAGCTCCAGGATCGGGAACAGGTCGGTCAGGTAGTCGCGCAGCACGTTGCCGGTCACCGAGATGGTGTCCTCGCCGCGGCGGATGCGCTCCAGCGAGAAGGCGGTGGCCTTCTCCGGGGACATGATCTCGATCTGCAGGCCCTCGGTGTCGTGCTCCGGGAGGTACTGCTTGACCTTCTCGATCAGCACGGCGTCGTGCGCACGGCTCTCGTCCAGCCAGAAGACGGCCGGGACGCCGGTGGCGCGGGCGCGGGTGACGGCCAGCTTGACCCAGTCGCGGATCGGCGCGTCCTTGGTCTGGCAGGCGCGGAAGATGTCACCGGCGGCCACGGGCTGCTCGATGAGCGCGGTGCCCGAGGCGTCGACCACGCGGACGGTGCCGTCGACCGGGATCTCGAAGGTCTTGTCGTGGCTGCCGTACTCCTCGGCGGCCTGGGCCATCAGGCCGACGTTCGGCACCGAGCCCATGGTGGCCGGGTCGAAGGCGCCGTGCGCGCGGCAGTCGTCGATGACGACCTGGTAGACCCCGGCGTAGCTGCTGTCCGGGATGACGGCCAGCGTGTCGGCCTCCTTGCCGTCCGGGCCCCACATGTGGCCGGAGGTGCGGATCATGGCCGGCATCGAGGCGTCGACGATGACGTCGGACGGCACGTGCAGGTTGGTGATGCCCTTGTCGGAGTCGACCATGGCCAGCGCCGGGCCCTCGGCCAGCTCGGCCTCGAAGGAGGCCTGCACGGCGGCGGCGTCGGCCAGCTTCTCCAGGCCGCCCAGGATGCCGCCGAGGCCGTTGTTCGGGTTGAGGCCGGCGGCGGCCAGCTCGGCGCCGTACTGCGCGAAGGTCTTCGGGAAGAAGGCCTTGACGACGTGGCCGAAGAGGATCGGGTCGGAGACCTTCATCATGGTGGCCTTGAGGTGCACCGAGAACAGCACGCCCTCGGCCTTGGCCCGGGCGACCTGGGCGGTGAGGAACTCGCGCAGCGCGGCGACGTGCATCACCGAGGCGTCGACGACCTCACCGGCGAGCACCGGCACCGACTCGCGCAGCACGGTGGTGGTGCCGTCGGCGGCGACCAGCTCGATCTTGAGCTTGCCGGCCTCGGTGACGACCACGGACTTCTCGGTGGAGCGGAAGTCGTTCTCGCCCATGGTTGCGACGTTGGTCTTGGAATCCGAGACCCAGGCACCCATGCGGTGCGGGTGGGTCTTGGCGTAGTTCTTGACCGAGAGCGGCGCGCGGCGGTCGGAGTTGCCCTCGCGCAGCACCGGGTTGACGGCGCTGCCCTTGACCTTGTCGTAGCGGGCCTTGACGTCGCGGTCCTCGTCCGACTGCGGCTCGTCCGGGTAGTCCGGCAGGGCGTAGCCCTGGGCCTGGAGCTCGGCGATGGCCGCCTTCAGCTGCGGGATGGAGGCCGAGATGTTCGGCAGCTTGATGATGTTGGCGCCGGGGGTCTTGGCGAGCTCCCCGAGCTCGGCGAGGGCGTCCGCGATCCGCTGGCCCTCCTCCAGACGCTCCGGGAAGCTGGCGATGATGCGCCCGGCCAGGGAGATGTCACGGGTCTCCACACCGACACCCGCGGTCGCGGCGTACGCCTGCACCACCGGCAGGAACGAATACGTCGCCAGGGCCGGAGCCTCGTCGGTGTGCGTGTAAATGATGGTCGAGTCAGTCACCGGTACTCCGCCTTCACGTCTACAACGTCTTGATATCAAGATATCTCGTGATCGCCCCTGCTCGACACCACCCCCCGCTCCTGAACCACTGAACTCTCCGGATCAGTCAGGTCCGGGCGCACCGGTCAGGTCAGGCTCACGGCCGCCTCGGGCGAGTGCAGGCCGAAGGTGAGCGACTGCTGGAGGTAGAGCTGCACGGTGCGCTCGTCGTGCGCCAGGTAGCCGATGGACAGGTCCTGCCCGAGGTGCAGCTCGAAGTCCCCGCCCCGGGTGGAGAGCACCACGCCCCCGCTGAGCGCCGGCGCCCAGACGATCGGCCCGTCCAGCACCCGGGCGATGTGCTGCCGAACGGGGTACCCGTGGTCGGAGGTCTCGTTGACGGCGGTGTACGCGTCGGCGCCGAGCAGCAGCGCGTACGGGCCGTCCACCCCGGCCAGCCGCAGCGCGGTGAGCGCGCGGCTGACAGCGTCCGGGTAGTCGGCCACCTCGGGCGGCAGCGGGATCGCCTCGTTGTCCGAGGCCGTCCGGATGCCCTCCACCGCCGCGTCCGGCCAGCCCTCGAAGATGATCCGGTCCTCGGTCAGCGCCATCGTCCGGGCGGCCGCCTTGGCGGGCTCCCAGTCGCTGTCCGCCGAGCCGCGCTCCACGTCGTCCACCGCCTCCCGGCCCAGCGTGAACGGCACCCGCAGCTCGACCACCGGGCGCACCCGGTGCGCCCGGGTCAGGACCTCCGGCTGCGGCGAGGGCACCGGCCGCAGGTGCCCCGTCCCGACGGCGGCGAAGTCCGGCCCCTCCGGCCCGGCGGTGTCCACCACGTGCCGGCCGGCGCAGTGCAGCTTGAAGGTCCGGCGGGTCTCCTCCTCGATCTCCGCCCAGGCGGCGGTGCTGATCGGGGCGAGGTGACGGTGCAGGTTGTCCACGGTTCAGAACGCCTTCGTCTCGATGGGAGCCTCGGTGGGAGTCTCGGTGGGAGCGGGGTGCAGCAAGTGCTTCAGGCCGCCGATGCCGAGCGAACCGTCACCGGTGGCGGCCTCGAGGCTCGCCCCGGCGGGGTCGGGCGGGTCGGCCAGGAAGTCGGCGTCGGGCACGAAGAAGAGCGAGCCGGTGACGGCGATGGAGAAGTCCAGGATCCGGTCGTGCGCGGCCTCGGCGGTGCCGAGGAACATCCGTCGCAGCATCTCCTCGGTCACCTCGGGCGTGCGGCAGTACCCGGCGAAGTACGTGCCGTACTCGCCCCGGCCGACGCTACCGAAGGCCATGTTCGCCCGCAGGATCTGCTGCTCCTCGCCGTCCGGCCCCTCGACCTGGTTGAGCGCCACGTGCGAGTCGGCGGCCTGGTCGGCCAGCTCCACGTCGGCGAGCTTGGTGCGGCCGATCACCCGCTCCTGCTGCTCGACCGTGAGCGCGTCCCAACTACCCAGGTCGTGCAGGTACTTCTGCACGACGAGGTAGCTGCCGCCGGCGTACTGCGGGTCCTCCGCCCCGACGTAGACCGCCCGCGCGGCCTTGGCGCCGACGGGGTTCTCGGTGCCGTCCACGAAGCCGAGCAGATCGCGCTGGTCGAAGTAGGCGAAGCCGTGCGTCTCGTCCACCACCCGGGCCGCGCCGGCCAGGCCGCGGGTGCAGCGGGTGGCCAGTTCGAAGCAGAGGTCCATCCGGGTGGCCCGGACGTGCAGCACCACGTCACCGGGGGTGGACGGCGCCAGGTGGCGCGGCCCGCGCAGCTCCCGGAAGGGGTGCAGCCCGGCCGGCCGCGGGCCGCCGTACAGCTCGTCCCAGACCGCCGCCCCCACCCCGGCCACACAGCTCAGCCGCGCCTCGGGCGCCCGCAGCCCGAGCGACCGCACCAACCCGCCCAACCCGGCCAGCCACTCCCGCACGGCCCGGTGCCCGCCCGGCTCCACCGCCAGCACCAGGAACACCGCCGCCCGGCTCGGCGGAGCCGGCACCACCTGCGGGTCCGGCTCACCCTGCACCTGTTCCAACCGCCCACTCCCCTCACTCGCACACGTCCGCAGGACCCTCCCCACCCGTGCCCCCGCCGATCACCACCCGCCCGCATCTCTCCCCCGTACGGCCCACCACTGCTCTGGTCGGCCGCACCGCTCCGACGCCCTGTCAGTGCGGCTGGCTAGCTTGAGTCCGTGCCCTCCCACCCGCCCGCCCGGCACCTGCTCCGGGCCAAGGACCTCGTCGACGCGCGGTACGCCGACCCGCTCACCGTCGCCGATCTCGCGGCCGCCGCCGGGCTCTCCCCGGCGCACTTCAGCCGGGCCTTCCGCCAGGCCTTCGGCGAATCCCCGCACGCGTACCTGCTCACCCGCCGGCTCGAACGGGCCGCCGCCCTGCTGCGGCACACCGACCGGCCGATCGCCACGGTCTGCCTGGACGTGGGGCTGAACAGCCTCGGCTCCTTCACCACCAGCTTCACCCGGATGTACGGCCTGGCCCCGGCCGCCTACCGCGCGGCCTGCCCGCCGGCGGCCGACCACGCCGTGGTGCCGAGCTGCGTCCGCCGCGCCTACGGCCGCCCGCAACACCGCACGTTTCGAGAAGACGGCGCCGATCCGCCGGGCATAGCGTGATCTTCGTCGAACCAACCGAACCAACCGAACCAACCGAGCCAGACCGCCGGTTCCGCCGGCTCCACCCGCGCTGCTTCCCTGGGAGACTTCCATGATCAAGATCGCCACCGCCCAGCTCTGGGTCCACGACCAGGAGGAGGCCCTCGCCTTCTACACCCAGCAGGTCGGCATGGAGGTCCGCTCCGACGTCAGCCTCCCCGAGATGGGCGGCTTCCGCTGGCTCACCGTCGGCCCGACCGGCCAGCCCGACGTCGCGATCGTGCTGATGGCCATCCCCGGCCCGCCGATCCTCGACGCCGAGACGGCCGCCCAGGTCCGCGAGCTCACCGCCAAGGGCGCGGCCGGCACCATCTTCCTGACCACGGAGGACTGCGACGGCACCTACGCCGAACTCTCCGCCCGGGGCGTGGAGTTCAACGAGAAGCCGACCGACCAGCCGTACGGCCGCGACTGTTCCTTCCGCGACCCCTCGGGCAACAACATCCGCCTCGCCCAGCTCTCCCCGATGTAGCCCGCACCACCCCCGGCCCTCGCTAGGATCACGCGGGCGACCGCCGCCACCCGGCGCGGCGGCACCATCTTCCGGGGGCCGGCCGGTGCAGGACAACGACGACACACCGCAGCCCGACGGCGGCGACGGTCAGCGCGGCACCCCCGCGCCCGACCGTCGCCGCCGTCGTGTTCTGCTCCTGGCCGGTGCCATCGGCGCCCTGCTCCTCGCCGGCGCCACCACCCTGGCCTTGGTGGCCCGCGACCAACCCGTCGCCACGGCCACCCCCACCGCACCGCCTCGCAGCTCCACCTCCCCCACCCCGACCCTCACGCCCGCCCTACCGGCCGCACCACCACCGCCGTCGCCGACCCCCACCGCCACGCCCAGCGAGCCACCGACGACCACCCCGCCGCCGCCCGAGCCCCCTGCACCCACCCGCACCCACACACCCACCACCACCCCGAGGCCCACCCACCCGGCCTCGAACCCTTCCCCGATCAACCCCCGCCCCACCATCACCTACACCGGCCCGACCAGCTGCCCGCCCGGCTACCAACTCGTCCACTTCCCCACCGGCGCCGAGTGCATCACCGTCCAACAGGGCACCCCCATCCCACCCCCGGGCGCCTCCGTCCCCCCGACCGGCTGACCCCGGGCCCCGCGTCCGCGCCTCAGGAGCCGCCGGGCCCGGCGGCTCGGCGGTGCCATTCCTCGGCCGCGGCGGCCTCGCCCCGGAGCTCCAGGATCGAGGCCACCGCGGCGGCGGCCTCCGTGTCGCCCCGTTCGGCGCAGGTGTGGAACCACCGCTGGGCCTCGGCCAGTTCACCGCGCTCGGCCAGGCTGACGGCCAGTCGGTACATCGCCGCGTGGTCGCCCTGCTCCGCGCCGGCCCGGTGGGTGGCCTCGGTGCCGGCGGCGATTTCGGGGCGGTCGGGCTCGCGGTGGGAGTTGGCGTTCTCGGTCATCGGGCGGTCCGGGTGGAAGATCCGCCAGCCGGTCTCGGCCGTGGTCCGGATCGGGTAACCGCGCCAGACCGGGTCTCCCCCGGTGCTCACCTCCACCCCGAGCTGCCACTCCACGTCGTGCTCGCGGGTGTGCGCGGTCAGTCGGTACACCCGGCTCTCCCCGGCCGGGACGGTGTCGGGCAGGCTCAGCGGCACCGGGCCCGGGGTCATCTGGTCGGGCTCGTCCAGCCAGACCCGGATCTGCGGCATGGGGATGTTGACCGTCCCGGTCACGAGGACGGAGACCTTCCCGGGCGCGGTGCCCAGCGGCCGACGGCCCATCACCCGGAAGGCGATGCCGTGCACCACCGCCGGCCCGCTCGCCGGCGCGCTCACCCGGACCTCGACGCCGTGCCCGCTCACCTGGAGCTGCACGGGCCGCGGACCGGTCACCGAGCTCGGCGTGTGGACCAGCCGGAGCTTGCCGATGCAGGACACTTCAACGACGGCCCCGTCCACGGAACCACCCCCCCGATCTTCGATGACGACGACGGTGCTGCGGTGAAACGGAACGGCTCGCCGGCGAGGTCGGCCACGCTCGTCCCCGTCCGGCCGCCGCAGATCCAGTCCACCTCGGCCCGCCACTCGACCTCGAACCGCTCGCACCGGACGCTCAGTTCGAAGACCTCGGGGTCGTCCGGGGTGACCGTGTAGAGGAATTCCGGGCCTGCCAGGCGGGGCGGGTCACGGTCGAGGTCCACGGTGTACCTCCGGACCTCCGGGACCCCCGCCGTCGGCAGCTCCACCCCCTCCACTGGCGGCCGCCGGGCCACCACCACGATCCGCAGTGCGCGCAGCAGCACCGCCCGGTCCTCGCAGGCCTCCGCGTGGATCCGGACGGCGCCGCCGCTGCACGGCACCGCCTCGTCCCAGCCGCCCGGCGTCACGTACTCCGTGGCCACCACCACGCTGGTGAGCGCCAGCGGGCTCGCAGCCGGCGGCAGCCGGGGCGGCGAGGAGTGGACGTGCAGCTCGCCGATGCTGCCGGCCTGCACCACCTCCCGGGCCACGCCCGAGAACTCGTTCCGGACCAGCCACTCGCCCGCGGGCCGCCGGTCGTTCGAGCCGTCCAGGCCGCCGGTCTCTCCGTGCACAGCCACCCCCCGGTGTCAGGCCTCACCGGGGGCGCGGCGCTGCTCGCCGTGCCCCCGGCCAGCGATCGTACGGTCAGCGCGTGGCGGCCGCCAGGGCCGCGCGGAGGGTGGCGGCGTCGGCCGGGTGGCCCGGGTCGGCGGCGAAGTTGACGGCGTCGGACGGGTCCTTGAGGTAGGGGAGGCCGTAGGCCGGGGTGTCGGGCTGGAAGCGCCAGCTGTCGGCGAGGGAGCCGGCGTCCACCGCGTCGTAGCCGAGGGCGTCGAGCAGGGCCGTGGCCTCGGTGCGGGCGGTGGGGTCGTCGGTGGCGATCAGGAGGCCCGAGCGGTCGGGGGCGCCGGCCGGGCGGGCCAGGGAGAGCAGGTGGCCGAAGAAGATGTTGTTGAACGCCTTCACCACGCGGGCGCCGGCCAGGTGCTCCTGGACCAGCTCGCTGCTGGTGGCCTCGCCCGAATCGAGGCGGGCGATCTGCCCGTCCCGCTGGGGGTAGTAGTTGGTGGTGTCGAGCACCGTCTTGCCCACCAGGGCGGCGGCCGGCGTCTGGGCGTACGCCTTCAGCGGGACCGTCACCACCACCCAGTCGCCCGCCCGGGCCGCCTCCTCGGGCGTGGCCGCCCGGGCCCGGGGGCCGAGCTCCGCGACCAGGTCGGCGAGCGTCTCCGGCCCGCGCGAATTGCTGAGCACCACGTCGATCCCGGCCGCCACCGCGAGCCGGGCCAGGGTGCCGCCGATGTTTCCACTGCCGATGAGTCCGAGAGTAGCCATGTCTGACACAGTGTCGGCAGCCCTTCCGGTATTCCCGCCCCGCCCGAGGATCATCCTCTGGGAGGAGCGCGCGGCCAGGGTGCGGAGGGGTGCTCAGGGAGCCAGGTCGCGCCGTTCCAGCAGCAGGAAGGCCGTCACCAGCCCGGCCAGCCCCACCCCCACCAGGACCGCGAACGACCCCCACGGCACCGCGCCGTGGGCCAGGGCGTCGCCCGGCACGTAGTAGTGGAACGGGCTGACGAACCGCAGCGGCGCCGCCTTCGACCAGGCCAGGGCGGCGAAGTTGACGGCGAAGCCCACCGCGCCGAGGGCGATCGTCACCCCCACCACCTGGGCCCGCCGCCGCCCCACGGCCGAGACGGCCAGCGCGGGGCCGGTCAGCGCGAGGGTGAAGGCGAAGCCCAGCAGCCCGGCGGCGAACACCCCGCTCAGCGGCACCGCCGCGTGCAGCCGCGCCGAACTGCCCACCCCGACGGCGATCACCGCCGTCGCGGCGGCGTTGAGCACCAGCGAGACCAGCAGCAGTGCGGCCGTCCGCTCGGCGAGCAGCCGGCGCCGCGTCACCGGGCGGGTGACGAGCAGCTCGATGGTGCCCTGCTCCACGTCGGCCGCCACGGCCGCCGCCGCGAGCGAGGCCACCGCGGTGAGCTGGAGCGCGATCCAGAACGGGTGCACCAGCCCGGCGCCGAGCAGGCCCGGGTAGCTGGCGATCGACACGTCCCCGGTCGACCCGCTGAACGCCTTGAACGCACCGGGCGGCGTCCGCCCGCCCCCGCCGAACACCTGGCCGGGCGGCACCGCCGTGGCCACCGCCACGATCACCGCCTCGAACACCACCATCGCCAGCAGCAGCGCGACCAGCATCCGGCGCCGCCGGTGCAGCGCCAGCCAGAGCAGTGGGAACCGACTCCTCACGACGCCTCCTCGGGCTCGACGCCCTGCTGCTCCGGCCCCGGGCCCGTCGGCTCCGCATCGGCCCGGTAGAGGTCGAGGAAGGCCTCGTCCAGCCCGGCCTCCTCCACCGTCACGTCCGCGACCGGCAGCGCGAGCAGGCCGCGCAGCGCGGCCACCACCTCGTCCGGCGGGATCAGCAGCACCACCTGGTCGCCCTGCCAGCGCGGCGACCACGCCTCGGCGGCGCCGAGCGGCCGGGCGCCGAGCCCGTCGGCGAAGCCGAGCCGGACCCGCCGGGCCCGGGCCTCGCGCAGCGCGGCCACCGTCTGCACGGTGACCAGCCGGCCGCCCCGGATGATCGCCACCCGCTCGCAGCAGCGCTGCACCTCGGGCAGCACGTGGCTGGAGAGCAGCACCGTCCGCCCGGCGGCGGTGGCCTCGGCCAGCAGCTCGTAGAAGGTCTCCTGAACCAGGGGGTCGAGGCCCTCGGTGGGCTCGTCCAGCACCACCAGCTCGGGGTCGTGCTGGAGCGCCTGGACCAGGCCGAGCTTCTGCTTCATGCCCCGGGAGTACTCGCGGACCGGCCGGTCGAGGTCGGTGGGCCGCAGGCCCAGCCGCTCGCACAGGCCCTCCCGCCGGGGCGAGGGCGCGCCCTGGAGGTCGCCGAGCAGCCGGAGCGTCTGGCGGCCGGTCAGCTCGGGGTAGAGCCGCAGCTCGCCGGGGAGGTAGCCGAGCGAGGGGGCGAGCGCCCGGTGGTCGGCCACCGGGTCGAGCCCGAGCACCCGGACCCGCCCGGCGGTGGGGCTGAGCAGGCCGACCAGGCAGCGGATCGTGGTGGTCTTCCCGGCGCCGTTGGGCCCGAGGAACCCGAAGACCTCCCCGGCCCGCACGGTGACGTCCAGCCCGTCCACCCCGACCGTGCGGCCGTACCGCTTGGTCACCCCGCTGAGTTCGATCACGGCCCGCGCCCCGGCCGGGGCCGTACCCGCAGCAGCCATCCCGCCTCCTCCCGACCACGCCCACCGGCCGCCACCCACCGGCTACTCCATCCTCCTCCCCTCCCCCGCCTCCCGGCCAGCAGCCTGCACGGCCTGGTCGGCCGCCGGTCGGCTCACCGGTTCTCGACGTACTTCTTCAACGCCTCGTTCAGCGCGGTGAAGTCCTCCTTGGTCCGCTCGATCGCCCCGCCGGTGACCGGCACCAGCACGCCGGAGAAGTTCTCCGACTGCACCAGCAGGGTGCCGCCGGTGCCGGTCGGGCTGAGCCGGAAGCCGTGCTCGCCGTCGAACAGGCCGGGCAGCAACAGCTTGCCGAACCACCGGAGTTCGACCCCGCGCTCGGCGGCCAGCACCTTGGGCTTGAAGGTGATCGGGCGGCCGTGGGCCGGGTGCATCCGCAGCACCAGGGTCTCGCCCACCGCCACGGTGCCGCTCGCCTCGCGGATGAAGGGGTTCCAGTCGGGGTAGGCCGGCAGGTCCGCCAGCGCCGCCCAGACCTCCTCGGCCGGGGCGTCGATCTCGATCTCGGCGAAGATGGTCTTCGTCATCGTGCTGCCTGTTCTGTGCTGTGCCGTCCCGCGCCGTGCCCCGGAGGTACGCCGTGCGGTACGCCGTGCCGATCGCTTGCCGTTCACTTGCCAGTCGGACCGTGCCCGTACGCATCCGGTCCGACACCATCAGTTACCACACCCCGAGGGCGGATCGGCCATCCGACGGAGCGCGCGACCCCCACCGCACGCCCTCCCGCACGCCGGGTACCGTGCAGTCCGGGGACGGCGACCGGGCCGCCCGACGGCGCCGGCCCAGCCGGGCCGCCACGCGAAGGGGAGACCGCCATCAGCACGCCCAGCCCGTCCGAGGTCCTGCGCCGAGTCGCTTCGGTGGGGCCGTACTTCGCCGTCGGTCTCGGCGCCCCGGGCGAGCCCGCGCCCGGCGGCTTCACCCCGATCCGCGAACTGTACGCACCCGGAGGGCCGTTGACCGTCCGGGTGGCCGCCGCGACCGGGCAGCTGCGCACCTCGGAGACCCGGGTCGCGGTCTCCGTCCTGCACCTGGGCCTGGCCGCCCGGCTCTGGTCGGTGGCCCTGGGCGCCGCGGCCCTCGGCCCGGGCCTGCCCGAGCTCGGCCCGGACACCCTGCACCACCGCTGGCCCGCCGACGGCCCGCTCGAGCTCTGGCTCCCGGCACCGGAACCGGAACCGGCCGCCGGCCATGCCCCGGACCTGGCAACCGCCGTGCACCGCACGGTGATAGGCGGTCACCTCACCCCCCTGCACGACACCCTGCGCGCGATCACTCCGATCGCCCCCCGCCTGCTCTGGGGCAACGCCGCCTCCGCCCTCACCGGCTCGCTGCAGATCCTGCACACCCGGATCGCCCCCACCCACCCGGCGGCGGCCGCCACCGCGCTGCGCGTCACCCAGCAGCTGCTCGCCGCGACTCCGCTGCTCGGCACCGGCGTTCTCGCCCCTGACGAGTTCTCCCCGCCCTCCGCCCCGCAGCGCTTCCGCCGCTCCACCTGCTGCCTCTACTACCGGCTGCCCGCCGGCGGCACCTGCGGCGACTGCGTGTTCGGCACCCGACCGCCCCGGCCGCGGAGTGCTACGCCCACGATCTGACGCCCCGTCAAGTGATTGACCGTCAGTCAGGCGGATGGCAGCATCGGGCCATGACGAAGCCTGGTGCCCCGATGCTCCGCGTCCGCACCAGCCTTCCGCAGCGGGCCGTGCTGACCACGGTGGCGGCCGTGCTCGCCCTGCTCGGCCTCGGCGGGGTGCTGGCCGGTACGGCGGGTGCGGCGGTCGGCGGCGGGTCGGCGCTCCTGGTCGCGGCCGTACTCGCGCTGCGCTCGCTCCGCTCGGGCATCGAGGCCGATCTGGACGGCATCACCAGCCGCACCGTCGAGCGGACGCAACGGCTCCGCTGGTGCGAGATCAGCTCGATCCAGCCGGGCGACGCCCGCTCGGCCTCCCCCGTCCCGGCCACCGCCCTGGTGGCCACCACCACGGCCGGGCGCCGACTCGTCCTCGGCGGCCTGGTCGGCCCGGCCACCCGGCGCAACTCCGTCCGGCTGCAACTCCTGCGCGCCGAACTCGACCGGCTCGCCGCCCGCCACCACCGCGAGTGCGCCACCTGCTCCGCCACCCCCTCCTGACCTCGGCCGCCCGCTGCGGCGGAACCGTCCACCCCCCTCCCCGCGTATCGGCAGGCGAAGCCCGCCCCACCCGGACGGAGGACCGAGGATGCCCCGCACCGCCGCCACCCTGACCTGGCGACTGCTCGCCCTGCTGCTCCTGTTCACGGCGGCGGTGGCCGGCGCGCTCGCCGTCTGGTCCCTCGCCGCCCCGGTGCCGAGCCTGCCGCTCGCCCCGCCCCTGCTCACCGGGCTGGCCGCCCTGGTGCTCGGCACCTTCTGCGCCCTGATCGGCTGGCCGCAGGACGGCTGGCAGGTCGTGCTGGTCTCGCTCCCGCTGATGGCGCTGCTCTGGATCGCCGCCCTCACGGCCGACTTCGCCTACACCTCCGTCCACAACTGGGACCGCACCCCCCTCGCCGTCACCGCCACCCTCACCGACTGCCGGGTCGACGCCGTCCACGGCGACGGCGACTCCGGCCGCACCGAGAAGGACAGCTGCGTCTACCACTACACCGTCCTCGGCCGGACCCACACCGAACGCCACGACTCCCCGGGGGCCGAGCACGACGGCAACCAGCTGCAGATCTGGCTCAACCCCACCACCGGCGAGATCGGCGAACACTCCCTCACCAACGTCGTGTTGATCTCCGCCCTCGCCCTCCTCGCCGCCACCCTCGCCCTCCTCGGCGCCTGGACCGCCGCCCGCGCGGCCCTCGGCCACCCCGAGGAGGAGGCCGGCTGACCGGTCATTCACCCCTTCCGGACCGGCCATCGCTGACCGGCCAGGAGCTCGGCGGAGCGCCGTTTCCGCAGGTCAGCGACCCGAACAGGCAGCCGGAGCGGGCGATCGGCAGGGCTTCCCGGGCATCGCGGGCGAGCGTAGCGTCCCCCGGCACCAGGGCAGTTACCTAGCAACGGGGGAATCGTGGCGCTCGAACTACCGGCCGAACTGGAACCGGTCCTCGGCCTGTTGGGGGTCGAATGGCCGCAGGTGAACGAGGACGAGCTCAATCGGTTCGCGGACGAGCTGCGCAAGTTCGCCTCGGCGATCGACTCGACGCAGATGGCGGCCGACAAGGCGGTCAGTGCGCTCGGGCAGGTCTACCACGGGGCCTCGGCCGACCAGTTGGCGCAGGCCTGGTCGGCGATCTCGAAGTTCTCCGAGCTCGTGGTGCAGGGGTGCGGGCTGGTGGCCAACGCGGTCAGTGCCGCCGCGATCGTGGTCGAGATGTGCAAGGGCGGGGCGATCGCCCAACTCGCGGTGACCAGTGGCGGGCTGGCCACCGCCGCGGCCACCGCGCCGTGGACCACGCCGGCCGTGCTCGCGACCGGTAAGCAGATCGTCTCGCAGATCCTGGAGTCGGCCGTCACCGAGCTCGGGCACGCGCTCGCCCAGCCGGTGGCCGATCTGGTGGACACCGCCGTGAAGGCGGTGACCGGCGGCGCCTCGGCCGGTGCGGGCGGCTCGGCCGGGCAGGGCTTCGGGGTGGACCTGGCCAAACTCGCCTCCACCGCCCTCCAACTGCGCGGCCACGCCGACGACGTGAACAGCAGCGGCAGCGCCTTCCTGCAGATCTTCGACTCCATGGACCTCGGCCAGCCCGGCGAGATCATCGGCAAGGTGGTGACCGAGGCGGCCGAGCAGATCGCCACCACGGTCGGCACCGAGGTGCTCAAGCGGCTGCTCAGCTCCTTCACCGGCACCGCCGACAACATGGACCAGATCGGCAAGAACCTCAGCCAGAACGAGGACGAACACTCCCGCCTGATGAGCAACCTGCTCTCCGCCCCGACCCCGGTCGCCGCGCTGACGCCCGGCCGGCTCGCCGGCACCAGCACCCTCTCCACCGACTCGGCGGCCGGCCCCTCGGCCTCGCACACCGGCATCGACAGCCTGCGCCCCCGCCTGGGCACCACCAACGCGGGCGGCTACGACGGCACGGACGGCGGCACCGACGGCGGCGACGGCACGGTGAACGCCGGTCAGCCCGGCACCCAGCCCAGCGTGGTGCTCCAGCAGAGCGAGTCGCCGACCTCGCACTCCCTGCCGACCGCGCCGGTCCAGTCGGGTACCACCAACCCGGGCTCCACCGGCACCCGCAGCTCGGCCGACGCCCCCGGCGAGGAGCACCCGACCGCCACCACCGCCGGCTCACCCGCGGCCGGCGCCGCCAACAACACGTACGGCCGCACCGGAAAGAGCAACGGCAGGAGCACCAACACGGGCACCACCGGGACCGGCACCGGCACCGGCAGCCGCCCGATCCAGGATCTCGGCGTCCAGGGCCGGGCCAAGCGGGCGAAGGCCGAGGAGGACGAGGAGCGCGCGCGGGCGGAGCACCGCCCGGCCGAGCTCCCGGACGGGCTGCCCGCCGAGCTCCCGACCGAGGAGGCGGTGGAGGCCGGCCGCTGACCCGGGGACGGGAACGCGGGCAGGGCCCCCGTCGCTCGGGGGCCCTGCCCGCCCTCTCCGGCACTGCGGTGCGCACTCCGTGCGCGCACCTCAGGCCCGCTCCGGCTCCCGCTCGTACAGGCGCCGCGACCAGACGTAGGAGACCGCCGCGACCCCGACGCACCAGGCGAGGGTGATGACCAGGTTGTCACCGATCGCCGTGCCGGTCAGCAGTCCGCGCAGCGTCTCCGTGACCGGAGTGAACGGCTGGTACTCGGCGAACCAGCGCAGGCCGGTGGGCAGCGAGTCGGTGGGCACGAAGCCGCTGCCGAGGAAGGGCAGCAGGATCAGGAACATCGGCGAATTGCTGGCCGTCTCCACGCTCTTGGCCGAGAGGCCCAGGCCCACGCAGAGCCAGGTCACCGCGAAGGTGAGCAGCAGCACCACCCCGAAGGCGGCCAGCCACTCGGCCGGGTTGGCGTGCGGGCGGAAGCCGACGCCGATCGCCGCCAGGGTGACCACCACGACCCCGGTCATGGTCTGCACGGTGGCGGCCACCACGTGGCCGGTCAGCACCGAGGAGCGGGCCACGGCCATGGTGCGGAAGCGGGCGATGATGCCCTCGGTCATGTCCTGGGCGACGGCGATCGCGGTGCCCTGGGCGGCGGCGGCCACCGCCATCAGGATGATCGCCGGGGCCACGTAGGCGGCGTAGGCGGCCCGGCCGCCGTGCACCCCGGCCGGGGTGCCGGCGCCGAGGCCCGAGCCGAGCGTCCCGCCGAAGACGTAGACGAAGAGCAGCAGGAAGACGATGGGCATCAGGGTGACCATCAGGGTCAGCGAGGGGTAGCGCTGGAGGTGCCGGAGGTTGCGGCGCAGCATGACCTTGGCGTGGGTCAGCACGTGCGAGCCGCCAGTGGTGGCTGTTGCGGTGCTCATGATCTATCAGGGTCCCTTCCTGATGATTCCTGCTCAGTTCCTGCTGGTCAGGGCGAAGAAGACGTCGTCCAGGTCCGGGGTGTGCACGGTGAGCGCCTCGACCTCGATCGCGGCCTCCTCCAGGCGTCGCAGCACCGCCCGAAGGGTGACCACCCGTCCGTCGCCCGCCAGTTGGAGGGTGAGCGCGTCCTCGTCCCGGCCGGTCGGCTGCAGCAGCGCGGCGGCGGCCACCAGCGCGGCCCGGTCGGCGAAGGTGAGTTCGAGGTGGCCGCCGGGGATCCGGGCCTTGAGCTCGGCGGGGGTGCCCTCGGCCACGATCCGGCCGCCGTCGAGCACCGCGACCCGGTGCGCGAGCTGGTCGGCCTCCTCCAGGTACTGGGTGGTGAGCAGGATCGTGGTGCCCTCGGCGACCAGGCCCCGGATGATCTCCCACATGGTGCGCCGGCTGCGCGGGTCGAGCCCGGTGGTCGGCTCGTCCAGGAAGATCACCGCGGGCCGACCGACCAGGGTCATCGCCAGGTCGAGCTTGCGCTTCATCCCGCCGGAGTAGGTGGAGGCGGGCTTGTCGGCGGCCTCGGCGAGTTCGAACCGGGCGAGCAACTCCTCGGCCCGGCGACGCCCTTCGGCCTTCGGCAGCAGGTGCAGGTCGGCCATCAGCAGCAGGTTCTCCCGGCCGGTGAGGTAGCCGTCAACGGCGGAGAACTGCCCGGTGACGCCGATCGAGCGGCGCACCGCCTGCGCGTCCCGCGCCGGGTCCTGGTCGGCGATCCGGATCTCGCCCGCGTCGGGGCGCAGGTAGGTGGTCAGCAGGTGGACGGCGGTGGTCTTGCCCGCGCCGTTCGGCCCGAGCAGGGCCAGCACGGTGCCTTGGCGGACCGTCAGGTCGATCCCGTCCAGCACGGTCTTCTCGCCGAAGGACTTGCGCAGCCCCCGGGCCGATATCGCGGTATCGGTCAGCGTGGCGGTGGCGCTCATGCCTGCTCCTCCAGTCGGGCCGTGCGGCGGATGACGATGTCGCCGAGCTTGGTCTCGGCGTGCACCTCGACCTTGTCCACCGGCTCGCCCGCCTCGGGCGCCTCGGCGGCGGCCAGGTCGTTGTAGACCCGGCCCACCTTGGTGTCCAACTCCAGCCAGGCGGCGCTGCCGTCGCGCACGCCCACGTCCACCCGGCCGTTCTTCGAGGCGGCCACCACCTTGCCGCGGACCACCTCGCCGATCCGCACCTCGCCGTTGGAGTTGGTGGCGGTGATGTCGGAGAGCGCCCGGTCGACCGAGACCGCACCGTTGGAGACCTTCACCTTGGCGGTGCCGGTGACCACCCCGATCCGGACCGTCCCGTTGCCCGAGGAGACGTCGGCGCCGCCGTCCACCACCCCGATCCGCACCTCCCCCGCGCTGCTGTGCACCTGGGCCGAGCCGCTGACCCCGTCCACGCTGACCTCGCCGATCGAGGTACGGACCGTCAGGTCGCCGGTCTCGCCCAGCCGGACGGCGCCGAGGCCGCTCTTGAGCTGCACGCTGCCGAGCACCCCCTCGGCCAGGTAGTCGCCGAGCTCGACCTCGCCCCGCACGTCGGAGTCGCTGGGCAGGGTCAGCACCACGTCGATCGACTCGGGGCGCTTGCTGAAGTTGACGAAGCGGTTGCGCGGCTTGCGGGTGACCACGGTGAGCGTGCGGGTCACCTCGTCGTACTCGACCCGGGTGGCCTCGGCGGCCTTGACGTCACTGGGCTTGGCCGGGTCGGTCGGGCTGACCTCGACCACGGTGTCGGCGCCGTCGGTGGCGCGGATCCGCACGTCGGCGACGTAGAGGTCGAGGAGGACGACGATCGGGGACGAGGTGCTGAACGTCGAGCGGGACATCTCGGTTTCCTTACCGGGTTGATGGGTTGGCGGTGCGGGGCGGTGCCACGCCGGGCCGGGTCAGCGGGCCCAGCCGGTCCAGTTCTGGCCGACCCGGCCGGACTGCTCGGCCGTCCTGGTCGGGGCGGGGGCGGACCGGCGGCCCTCCTGGGCGAGGCCGGCGGCCGCGGCCCGGACGATCCAGGCGTTGGTGGAGAGCCCGCCGGCGGCCGCGGCGTCCTCGATCTGGCCCTTGAGACCGGCCGGCAGCCGGAGGTTGATCCGCACCATCGCGGCGTCCTCCCCCTCCACCACGGGCACCCTCACCTCGGCCGGCGCCGGCCCGGCCGGCTCCCCCACCCCGGGCGGCGGCGTCACCACGAAGGCCGCCTCGCCGCCCCGCAGCCGCACGTCCACGGCCCCGGGCGCCAGCTCGGCCGAGATCTCCTCGGCCGCCGCCGACAGCGCCTCCAACAGGGTCAGCCGCATCGCCGCGTCGAGCGGCAGCAGCAACCGGTCGGCGAGCGCACGGGCGTCCTCGCCGCCGACCCCCGCCGCCACGGTCAGCTCGCGGCGGAGGTTCTCGACGTACTGGGTGAGTTCCATGGCTCCTATAGTGGCACCACTATGGCACCACGGCAAGCCCATTCGGTGCCACGAAACATCACCGCAGCTCAGCGCCTACTCACCGGCATGTCACGACCCCAACACGACACCACCGCACCACCCCTTGGCACCACTCGCCCACCCACATGGCACCACTCCTGGCACCTCACTCCGGCAGCCGCAGATGGGAGCGGCCGCCCTCGTGGTCGAGGATGGCCAACAGCTCGGCGGGGCCGCCGTGGGCGCCGAAGGCGTGCGGGATCATGGTGGAGAACTCGGCGGCCTGGCCGGTCTCGACCAGGATCCGGCGGTCGCCGAGGGCCAGCTCGACGGTGCCGGAGAGCACGGTGAACCAGTCGCGGCCCGGGTGCACCTTGAGCAGGCTGGTGCCGGTCGGCGCCGGGCGGGTGAGCCGGAGCTTGGCCACCGTGGTGGACGGGTCGCGGCCGAGCATCCAGCGGGTGATGCCCCGGGCCTCGTCGCGCTGGGGCCGGATCACCACGTCGCTGTCGTCGGCCGGCTCCACCAGGTGGTCGATGGTGGTGTCCAGCGCCCGGGCGATCGCCGCCAGCTGGTCGAGGCCGATCCGCCGGTGGCCGGTCTCGATCCGGCTCAGCGTGGAGGGGCTGAGGAAGCAGCGGGCCGCGAGGTCGTCCAGCGAGAGGCCCATCGCCACCCGCAGGCCCCGGATCCGCTTGCGCACCAGCGTGTCGAGTTCGCCGTCTTCTTGCTTCATACGCAAGATGCTATGCGATTCGCGCAAGGCTCTCGTAGCCTCGAACCATGACCCACCACACCGCACACCGCCCCCACCAGCACGGCCACCCGGGCCCCGGCCACGCGCATGATCACGATCACGCCGCCCCCTCCGACGCCGAGCTCGCCCCGCTGCTCGACCTCGACGCCGAGGTGCTGCACGAGCACTACACCGAGCTGACCGACTGGCTGGCCGGGCACACCACCCAGGGCCCGACCGTCCGCCGGGTGCTCGACCTCGGCGCCGGCACGGGCACCGGCACCTTCGGTCTGCTCCGCCGCTTCCCGGCGGCGACCGTCACCGCCGTGGACAGCTCCCCGGTGCTGCTGGCCCGCCTGGCCGAACGGGCCGAACAGCTCGGCCTCGCCGACCGCGTCACTACCGTCGTGGCCGACCTCGACGCCCCCTGGCCCACCTTCGACGGCGAGGGCGGCGCGGACCTGATCTGGGCCTCCGCCTCCCTGCACCACCTCGCCGACCCAGCCCGGGCGCTGCGCCGCGCGTACGCCGCGCTGCGCCCCGGCGGCCTGCTCGCGGTGGCCGAGCTCTCCGGCTTCCCGCACTTCCTCCCCGACGACATCGGCCTGGGCACCCCGGGCCTGGAGGACCGCTGCTCGGCGGCCCTGGCCGCGCAGCACGCCGCCGGCCTCCCGCACCTGGGCGACGACTGGGGTCCGCTGCTCACCGGCGCCGGCTTCGAGCTCGCGGCCGAGCGGCACTTCGCGATCCACCTCACCGCGCCGCTGCCGGCCGCCACCGGTCGCTACGCCCTGGCCCGGCTCAGCCGCGTCCGCACCGGGCTGGCCGACCGCCTCTCCGCCGAGGACGCCGCCACCCTCGACCGGCTGACCGCCACCGAGGGCCCGGCGAGCGTGCTGCACCGCACCGACCTCACCGTCCGCACCGAGCGCGACGCCTGGCTGGCCCGATGCCCCGCCAACTGACCCATCCGTGAAGCGAGTTCACCCCGCCGGTGGCGCAACCGTGGTCGCCGCCCGGTACAGCGCCCGGGTGGCGGCTCCGAAGTAGGCGCTGTAGGAGATCTGCGGGGTGTCGCCGCCGGTGTGGTAGCCGCCGATCACCCCGACCACCGCCGTACCGCCCTGCCAGGCCACCAGCATCGGCCCGCCCGAGGTGCCGCCCACGAAGCCGTCGCAGGCGATCCGCTCGAAGGTACCCGGCTCCGCCGGGTCCTCGGGCGCCCAGGCGGTGGTCGCACTCGTGCAGTCCAGCGGCTTCGCCGCCCCGGCCGGGTACCCGATCAGCCGCACCGGCGCGTGGGCGTACCCACTGCCGGTGAGCAGCCCGACGGCGCCGACCACGTCCTCCAGCTGCCGCCCGGCCGGATCGGGCCCGGTCACCGCGAAGGCGAAGTCGTAAGCGGCACCGGCCTGTTCACCCCGGTCGTAGTACTCCTGCGGGACGTACACGCCGTCCGTCACCACCGGGAAGACGCCGAACGGCTTGAGCCCGTCGTGGTACTGCGGCACGAAGGCCAGGTGCCGCTCGGCCTCGGCCCCGGCGTAGCCCTTGAGGCAGTGGCCCGCGCTGAGCGCCAGGCCGCGGCCGGGGCTGTGCACCACCGACCCGCTGCAGGTGCGGCCCGTCCCGCCGGCGTCGGCCCAGAAGAAGGTGCCCACCTGCGGGATGCCGTCGAAGCTCCGGCTGGGCGGCACGATCTCCCCCGGCGCCGGCCCGTCCACCGGCACCCCACGCCCGGCCCGCCCGGCACCGGCCGCTCCCGCTCGCGCCTCCGCCGGTACCGCCGCCGCCATCCGCGCCGCGGTCCAGTACGCGGCGAGCCGAGCCGCCTCGGCGCCGCCCGGCACCGCCCCGCTCGCCCCCGGCGCCACCCCCGCCCCCACCAGCACGGCGGCCGCAGCCACCGTCACCCCCTTCACCAGACCCTTCCCGGCCACCACCGACCACCCTTCCGCCACCTGCACCGGTCGCACCCCCCATCCATCCCCCGCCTCCGCCCGAACAGTCCGGACGCTCCCGAACCCCCCTGCCGCCGCAGCGTCGATTCACCCTCCCGGCCCCCACCCGGACGGATAGACGAGTACACGAACGACTTGCTAAGGTCGCCCGTCATCTCCGCCGCCCCACCCCCAGGACAGCCCCATGATCGCCGCCTACCTCCCCACCGGCTCCTGGTGGGCCATCGCCGCGGCGACCACGGTCTTCTGGGTGGCGGTCATGCTGCCCGCCGCACCCACCCGGGCCTACCGGCTCCGTTACCTGGGCCTGCCCGTACTCCTCGGTGCGCTCCTGGCCCTCCGGAGCCACGGCAAGCACTTCACCCAGCAGGAGCTGCTGAGCTGCTACGCGCTGTTCACCTTCGCGTTCCCGCTCTTCGTGATCGGACGCTGGGAGGAGATGCGCGAGTACACCCTCGACCGGGAGGCCCAGAAGGCCGGGAAGGACGTCACTCCGACGCTGTCCCGGGGCGCCCGCGTCCAGATGTACGTGGTCACCGCGCTGCTGGTCGTGGGCACCGTCGCCATCCTGCTACCCGGGTAGCCCCTGGGCTGCGGCCCGTCGCCGTTCGTGGCTCCATGGGTACGTCCCGTGTGCGACCAGCGACCATGAGGTGACCCCGCGTGTCGATGTCCTACTTCGGGCCGAACGATCCGTTCGGCGACCTGTTCAACCGGTTCTTCGGGATGAGCCCGACGGCCTCCCCGCCCGCCGTGCAGCGGGTGCCGATCGGGCGGCTGCTCAGCGACTCGGCCCGGGGGCTGATCGAGGCGGCCTCCCAGCGGGCCGCCGAGGACAGCATCTCGGACCTGGACACCGACCACCTGCTCTGGGCCGCCACCCAGGTGGACTCCTCCCGGCGGATGCTGGAGCGGGCCGGGCTCGACCCGGACGCGCTCGCCGCCGACCTGCGCAGGTCGCTGCCCACCGCGGCCAGCGGCACCGGCGAGGAGCCGGCGCTCACCCCGGCCGCCAAGCGCGCCCTGCTCGGCGCGCACGCCCGCTCCCAGGCGGCCGGCGCCGACTACATCGGGCCCGAGCACATCCTCGGCGCCCTGCTCGACGGCGACCGCTCCGGCGCCGCCCAGGCCCTGCGACACGCCGCCCCCTCCCAGGAGGCGATGCGCAGCGTGCTGGACGGCTACGGCACCGGCGGCGACCGCAGCTCCACCGGCGCCCACCCGAGCGATACCCCGACCCTGGACGAGTACGGCCGCGACCTCACCCAGGAGGCCCTGGCCGGCAGGCTCGACCCGGTGGTCGGCCGGGCCGAGGAGATCGAGCAGACCGTCGAGATCCTCTCCCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGGGTCGGCAAGACGGCCATCGTCGAGGGACTGGCCCAGCGGATCGTCGCGGGCGACGTGCCGCAGAGCATCAAGGACAAGCGGGTGGTCACCCTCGACCTGACCGGTCTGGTGGCCGGCTCCAAGTACCGGGGTGAGTTCGAGGAGCGGCTGAAGAAGGTGATCGACGAGGTCATCGCCGCCGAGCAGAGCGTGATCCTCTTCCTGGACGAGCTGCACACCGTGGTCGGCGCCGGAGCCGGCGGCGAGGGCTCGATGGACGCCGGCAACATCCTCAAACCGGCCCTGGCCCGGGGCGAGTTGAGCGTGGTCGGGGCCACCACTCTGGACGAGTACCGCAAGCACATCGAGAAGGACCCGGCCCTGGAGCGCCGGTTCCAGCCGGTGCTGGTGCCCGAGCCGAGCGTGGACGAGACGGTGGAGATCCTGCGCGGGCTGCGCGACTCCTACGAGGCGCACCACCAAGTCCGGTTCACCGACGCCGCGTTGGAAGCCGCCGCCACCCTATCCGACCGGTACGTGAGCGACCGCTTCCTGCCCGACAAGGCGATCGACCTGCTCGACCAGGCCGGCGCCCGGGTGCGGCTGCGCGAGCTCGGCTCCAGCGGCGAGCACCGGCAGACCGGCGACCGGATCACCACGCTGCGCCGGGAGTTGAGCGAGGCCGTCGCGGACGAGGAGTTCGGCCGGGCCGCCGAGCTCAAGCAGCAGCTGCGCGCGGCCGAGGACGAGCGGGCCGCCGTGACCGAGCAGCGCGAGGGCGTGGCCAGCGTGACGGCCGAGGACATCGCCGAGGTGCTCTCCCGCCGCACCGGCATCCCGATCGCCCAGCTCACCGAGACCGAGAAGGAGCGGCTGCTCAAGCTGGAGGACACGCTGCACCACAAGGTGGTCGGCCAGGAGGACGCCGTCACCGCGATCGCCCAGGCCGTCCGCCGCTCCAGGGCCGGCATGGGCGACCCGGGCCGCCCGACCGGCTCCTTCCTCTTCCTCGGCCCGACCGGCGTCGGCAAGACCGAACTCGCGAAGGCGCTGGCCGAGTTGCTCTTCGGCGACGCCGACCGGATGGTCCGCTTCGACATGAGCGAGTTCCAGGAGAAGCACACCGTCTCCCGCCTGGTCGGCTCGCCGCCCGGGTACGTCGGCTACGACGAGGCCGGCCAGCTCACCGAGGCCGTCCGCCGCCGGCCGTACAGCGTGCTGCTCTTCGACGAGGTGGAGAAGGCCCACCCGGACGTGTTCAACCTGCTGCTCCAGGTGCTGGACGACGGCCGGCTGACCGACGCCCAGGGCCGCACCGTCGACTTCCGCAACACCGTGGTCATCATGACCAGCAACATCGGCTCCCGCCGGATCCTCGACCACCACGGCGAGGTCGCCGGCATCCGGGACGAGCTGATGAAGGACCTCGGCCAGCACTTCCGCCCCGAATTCCTCAACCGGATCGACGAGGTGATCGTCTTCCACGCACTCACCCGGGCCGACCTGCTCAAGATCGTCGACCTGCTGCTCCGCCGCAGCGAACAGCGCCTCAAGGCCCAGGGCATCACCCTCACCGTCACCGACGCCGCCAAGGAGTGGCTGGCGAACAAGGGCTACCAGCCCGAGTTCGGCGCCCGCCCGCTGCGCCGCACCATCCAGAGCGAGCTCGACAACCGGGTGGCCAACCTGCTCCTGGACGGCTCCGTCCAGAAGGGCGACGAGATCCTCGCCGACGTCGTGGACGGACAGTTGGTCTGCTCACTGGCCCGCCCGGCCGAGGCGTAG

Protein sequences of DBSCAN-SWA_1

>NZ_CP025394|884712:1006869|990525_991215_-|WP_104814821.1|DBSCAN-SWA
MATLGLIGSGNIGGTLARLAVAAGIDVVLSNSRGPETLADLVAELGPRARAATPEEAARAGDWVVVTVPLKAYAQTPAAALVGKTVLDTTNYYPQRDGQIARLDSGEATSSELVQEHLAGARVVKAFNNIFFGHLLSLARPAGAPDRSGLLIATDDPTARTEATALLDALGYDAVDAGSLADSWRFQPDTPAYGLPYLKDPSDAVNFAADPGHPADAATLRAALAAATR
>NZ_CP025394|884712:1006869|910955_911606_+|WP_104814774.1|DBSCAN-SWA
MITSEIVLLRHGQAHCNAAGLVGGPATCTGLTDLGRHQVEQAAELLAAEHAASPFTALYAGPRLRLQQTGQILALAMGLQLLTDPGFDGPEHGDADGRPWREVKDSFGGAPHTRPDTPWARGSDTWNGYLQRAGAHLRKLLTRHQTGRLLLAAHGETVIAAHVLLLGLPLGSVNGFSVDHASLTRWQHHRNQRGQQRWLLHSHNNTAHLAPPPEQP
>NZ_CP025394|884712:1006869|962737_963514_+|WP_104814802.1|DBSCAN-SWA
MQDTRVDEYLARIGAARPARPDLDGLRRLQEAHLLAVPFENLSIHLGEPVSLDEDALLAKIVDRRRGGFCYELNGAFAALLTALGYRVDLLSARVFGAAGLTTPFDHLALRVQLDGPWLVDVGFGRFARQPLRLDTREPQPDPAGTFTVEATPEGDLDVTMAGEAQYRLDQRPYALTDFAPTCWYQTTSPASHFTVSSTCSRPTPAGGRVTLAGTRLITTTPDGTRTEADLTPAEALTAYRDHFGITLDRLPGLPGRP
>NZ_CP025394|884712:1006869|950014_951094_-|WP_158702018.1|transposase|DBSCAN-SWA
MHGGRRAGTAVAVVLEAKARERLVRTVASAKSEVRVVLRARIVLAAADGLANGAIARELDVSVNTVRKWRGRFAALGLGGLRDAERSGRPRSYGPEVRVAIVATATSAPPYPESTWSHRAIARRVAGTCFAPVSASQVGRILAGLDLKPHKVRGWLTRRDTPDFWQRAAEVCALYLDPPEGAVVLSIDEKTAIAARSRRCPGRPARPGEPVRQEFEYRRHGTASLVAALDVCTGEVLTEVITRNDAVTFTAFLEQLDRAIAPGKEIHVVLDNGSSHTARHTRAWLAARPRWHVRWTPPHASWLNQVELFFSALTRRVVRHGDFSSRDDLIDKLQAYVIGHNDTARPYRWTYEGTPLKAA
>NZ_CP025394|884712:1006869|939070_939910_+|WP_104814788.1|transposase|DBSCAN-SWA
MTDRRPYPSDLSDARWALVEPTLSAWRRARTERALAFGRPPEHELRDLLDAILYVDRTGIPWRYLPHDYPPWETVYAYFARWQKEGVFEQLNGLLRRLVRAAEGRDPEPTACIIDSQSVKTSTNVPAATQGIDVGKKIAGRKRNIVTDTIGLLLMVLVTAASVQDGTAGRQLLTVVATNHPTVHKAWADMGYKNAVVEHGATLGIDVEIVRRDPATRGFVVQPRRWVVERTLGWLMNHRRLARDYEALPARSEAMIHVAMINLMTRRLTGESTPTWRGT
>NZ_CP025394|884712:1006869|908776_909322_+|WP_104814471.1|DBSCAN-SWA
MPSVVGLLEQRELTARRRVDELREEADRIQAELVAAEREWSEWVIARSRVGEVLSPGEGDIAGPDAVEKPSDRGEPPALPASSAAAKPKSVVPMWRAGLARSALSADYQRIVQALADRGRLGQGPLTCQEMAACFGLDPVPAKIEALRSKAKRLTARGWLVEPEPGRFTLAMALAGPGGGS
>NZ_CP025394|884712:1006869|914545_915664_+|WP_174805623.1|transposase|DBSCAN-SWA
MVGVDRRTGQKWRNGRKPTGTQRTAPAPLDLDGKPAPPTGPAGRSRFLTEAERIHIADRLREKATVRAIAAELGRSPSTVSREITRNAHPVSGAYRPHAAQARANARRPRPKPRKIGQTPELRDFIQHLLDLRWSPEQICQALRETFPDRPEMHVAVETVYQTLYLQGRGELRREVAAALRTGRARRIPHRQAATRRPRFAHPMVMISERPAEADDRAVPGHWEGDLIIGKDGASAIGTLVERATRYVMLLHLPAGRGAEQVRDALVATVQTLPAHLRRSLAWDQGAEMARHADFTIATDVPVYFCDPASPWQRGSNENTNGLLRQYFPKGTDLSVHSPEHLAAVAAQLNGRPRKTLDWDTPAERLHKLHTA
>NZ_CP025394|884712:1006869|1004382_1006869_+|WP_104814834.1|protease|DBSCAN-SWA
MSMSYFGPNDPFGDLFNRFFGMSPTASPPAVQRVPIGRLLSDSARGLIEAASQRAAEDSISDLDTDHLLWAATQVDSSRRMLERAGLDPDALAADLRRSLPTAASGTGEEPALTPAAKRALLGAHARSQAAGADYIGPEHILGALLDGDRSGAAQALRHAAPSQEAMRSVLDGYGTGGDRSSTGAHPSDTPTLDEYGRDLTQEALAGRLDPVVGRAEEIEQTVEILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPQSIKDKRVVTLDLTGLVAGSKYRGEFEERLKKVIDEVIAAEQSVILFLDELHTVVGAGAGGEGSMDAGNILKPALARGELSVVGATTLDEYRKHIEKDPALERRFQPVLVPEPSVDETVEILRGLRDSYEAHHQVRFTDAALEAAATLSDRYVSDRFLPDKAIDLLDQAGARVRLRELGSSGEHRQTGDRITTLRRELSEAVADEEFGRAAELKQQLRAAEDERAAVTEQREGVASVTAEDIAEVLSRRTGIPIAQLTETEKERLLKLEDTLHHKVVGQEDAVTAIAQAVRRSRAGMGDPGRPTGSFLFLGPTGVGKTELAKALAELLFGDADRMVRFDMSEFQEKHTVSRLVGSPPGYVGYDEAGQLTEAVRRRPYSVLLFDEVEKAHPDVFNLLLQVLDDGRLTDAQGRTVDFRNTVVIMTSNIGSRRILDHHGEVAGIRDELMKDLGQHFRPEFLNRIDEVIVFHALTRADLLKIVDLLLRRSEQRLKAQGITLTVTDAAKEWLANKGYQPEFGARPLRRTIQSELDNRVANLLLDGSVQKGDEILADVVDGQLVCSLARPAEA
>NZ_CP025394|884712:1006869|1001805_1002723_+|WP_104814832.1|DBSCAN-SWA
MTHHTAHRPHQHGHPGPGHAHDHDHAAPSDAELAPLLDLDAEVLHEHYTELTDWLAGHTTQGPTVRRVLDLGAGTGTGTFGLLRRFPAATVTAVDSSPVLLARLAERAEQLGLADRVTTVVADLDAPWPTFDGEGGADLIWASASLHHLADPARALRRAYAALRPGGLLAVAELSGFPHFLPDDIGLGTPGLEDRCSAALAAQHAAGLPHLGDDWGPLLTGAGFELAAERHFAIHLTAPLPAATGRYALARLSRVRTGLADRLSAEDAATLDRLTATEGPASVLHRTDLTVRTERDAWLARCPAN
>NZ_CP025394|884712:1006869|935802_936687_+|WP_104820641.1|transposase|DBSCAN-SWA
MCVCSCKPSYDSSLTDAQWAMIEPLLPGRDPRRGGRPLKFPRRLVVDTVLYVLVSGCAWRLVPHDLAPWDAAYRWFRAWSADGTWDRVHDVLRDRVRVADGRDPQPSAAVPDSQSVRSHQGGEAIGYDAGKRVRGRKRHLLVDSCGLVLKAVVHSASVQERAGAKLVLAGIRGLFPRVGLVWVDGGYVNAIDAGLVGWAAAHEDLTVVAVPRNADVKGFQVLPRRWVVERTFSWLGRCRRLARDYERKTAHAEAMIKVAMIRLMAARLAGEEVEPRGPIETEAARRLADDLKNE
>NZ_CP025394|884712:1006869|957634_961057_+|WP_158702021.1|DBSCAN-SWA
MSEDGSGGVRALRMWARDAIERADRVIPFTEVEWFSRMQAFAEPGFIDRTIEELTHLEPLLPAPDDPRNAVLTRLGVLLALRYAGPEGGSAEDRTRGLAYLGQVRSAEPRATDWERQGAAFGLLALRNPRPELGRRDGRPADHAALMDWYIKDGGAFQADDLPELFADARALPLPTELRQQLDQAGAGAALLSHLLRPGGPTATAEEVIDAFPADFPLLSELRAMLNLRDRLNHREPATETSTTPEPTTEPDAGPARGRARVLSHLESVLPGALSADLLREMQEELARGAADPALDPEDRATDAVVALLPDAMNALRGNDPALLHSVLGRLAEVADILPEGHRLAPVLTFLRAAYLGVADRIGGNRQDAELGARLLEAVEERFTEGGVSPVLTPIVRLLSLESRFSRAEQAADPAALDGVIDELLSLRESVATDPDLHYLTVVELALAQLARGDLLGDAEERHRALALLEEAERQAGNLHPVLQEAAAQLAGVRKLGRGPDEDPALIDEVLSVPRPRATGAGDWELQQATARLARHTRTGDRADLDAAIAALEGLRERTREGRGTTIAVETYWRLAEAYADRADLTEDPEDQRAAVASAVESLRAHSADVLLEAGAEDGLLAARRASERGLLVARWAAVSDLLPEAVEALELGRAMVLQAAADTADLPERLAARGAQELAEAWRAAAAGAPAGAGLPSDLRRRALEALGYRQGVSGTPTLDELCAALDTADTDLLVYLVPGDGEQPGLGIVLGPAFGVQAFLAPALSDAQSGPLHAYLDAAAARSGQQDAEADRAWQEALAGLCDWAWLGVMGPLHELGTTLRAADPADPAPPRVVLVPCGRLGVVPWHAARVYEGGRYRYACERLLLSYAASGRQLLRAVERRPIPVESAPVLLADPRLDLLHAEREVAALHADCYPNARLFGEYYDPPAPPSAAGTPAEVLALLTTGQKAVSLLHVASHGSAGPRPTESALVLARPVGTAPGPTVASAPDAGLLTVAQLLDGEGLTARPAGPLVVLSACETDLSTRDHDEALTLTTAFLARGARNVVGSRWTTADGASAVMMAVFHHHLTVARLDPAHALQATQRWMLDPKRRLPTEVRGLPASYGQLPGLHRPEVWAAFIHQGHPGPAPVSLLSPPD
>NZ_CP025394|884712:1006869|992126_993107_-|WP_104814823.1|DBSCAN-SWA
MAAAGTAPAGARAVIELSGVTKRYGRTVGVDGLDVTVRAGEVFGFLGPNGAGKTTTIRCLVGLLSPTAGRVRVLGLDPVADHRALAPSLGYLPGELRLYPELTGRQTLRLLGDLQGAPSPRREGLCERLGLRPTDLDRPVREYSRGMKQKLGLVQALQHDPELVVLDEPTEGLDPLVQETFYELLAEATAAGRTVLLSSHVLPEVQRCCERVAIIRGGRLVTVQTVAALREARARRVRLGFADGLGARPLGAAEAWSPRWQGDQVVLLIPPDEVVAALRGLLALPVADVTVEEAGLDEAFLDLYRADAEPTGPGPEQQGVEPEEAS
>NZ_CP025394|884712:1006869|951141_951471_+|WP_104814794.1|DBSCAN-SWA
MPKNPPESMQHHLRQRLNRHARERWPHVDAIGVRFRAGFAYLAAELPGGQSLPLCRLRFTGVLHTWGFALYLASSDSYKDNILPSELPAGSPEEALDCAGDLYLSGLAI
>NZ_CP025394|884712:1006869|944689_946384_+|WP_158702017.1|DBSCAN-SWA
MTFSKESEQVALQYLQTVVVIDDGLLLGVEDASGEAEVVDPVDPLEVDPAEGEGETKTQGSAGQDLDGAPDDLLRGEQLIRGFAEKGLVCGLLKPSSGQELEDIKSGQYQRLFARADVMVLDWSLARDEGATTRKLILDLVGKSEERVKRLRLICIYTNSPNLASIQESIALDLRADGINSFVGGEMERDWFVQGGDFRIAILGKTGVSRLPHFSEAEVPEGELPSRIVTEFTRLAHGLMPALALNSLAILRDNAPMLLQRFNGNLDPAFVSHELLTGQGRRFAVQLISREIQSILEAADAGSVLSHQNVKAWAATKLEAVSSDELEVKMGNSRRKFKKLDVLTAISQEEFSLQTFRELKTTDGLKLGAAKLASLSSLFSPDPDALDSDEQLGLLSCLSRDLHGRYDGTRMPTLQLGSIVAQREQDSSGEVRYWLCLQALCDSERVTGPRGFPLIPLRPASNGAEFDFLIMDHSGVRVQLSGSSRPFEMKVVEFSPEQGDDVIRATRRDGELVFQDCGHGSWYWVAELRPEHALRVSHQMASQISRIGLDESEWLRLSGNNKKS
>NZ_CP025394|884712:1006869|934566_935241_+|WP_104814785.1|DBSCAN-SWA
MDAGEGLLQPATVVLNASPRTGRVRAVLRWYVDGRSTTAVLGDVDRPTRAGNLREGWRLAEEAGLLSSAPVPESSWASSPATRKSMRANRAKDTKPELRLRSLLHRDGLRYRVSVRPVPTLRRTADVVFTKAKVAVFVDGCYWHGCPEHGSLPATNRGFWTEKIKGNKARDAETVRLLEQAGWKVLRIWEHVPPEEGARLVAETVSAARQEARAARGSEKAAVE
>NZ_CP025394|884712:1006869|993220_993655_-|WP_104814824.1|DBSCAN-SWA
MTKTIFAEIEIDAPAEEVWAALADLPAYPDWNPFIREASGTVAVGETLVLRMHPAHGRPITFKPKVLAAERGVELRWFGKLLLPGLFDGEHGFRLSPTGTGGTLLVQSENFSGVLVPVTGGAIERTKEDFTALNEALKKYVENR
>NZ_CP025394|884712:1006869|961031_961511_-|WP_104814800.1|DBSCAN-SWA
MIIQDGGAVSVRPVRPEELAAVAVLAAEHAAYERAGAPAADLAERLHGLLFGPGPARLRVLVAELDGGLVGYASCAPELSTWEGREYLHLDCLYVRAGVRGGGVGARLVEAVVAEARALGFGEVQWQTPEWNEGAVRFYERLGAVAKPKLRFSLGVTGD
>NZ_CP025394|884712:1006869|983056_985276_-|WP_104814813.1|DBSCAN-SWA
MTDSTIIYTHTDEAPALATYSFLPVVQAYAATAGVGVETRDISLAGRIIASFPERLEEGQRIADALAELGELAKTPGANIIKLPNISASIPQLKAAIAELQAQGYALPDYPDEPQSDEDRDVKARYDKVKGSAVNPVLREGNSDRRAPLSVKNYAKTHPHRMGAWVSDSKTNVATMGENDFRSTEKSVVVTEAGKLKIELVAADGTTTVLRESVPVLAGEVVDASVMHVAALREFLTAQVARAKAEGVLFSVHLKATMMKVSDPILFGHVVKAFFPKTFAQYGAELAAAGLNPNNGLGGILGGLEKLADAAAVQASFEAELAEGPALAMVDSDKGITNLHVPSDVIVDASMPAMIRTSGHMWGPDGKEADTLAVIPDSSYAGVYQVVIDDCRAHGAFDPATMGSVPNVGLMAQAAEEYGSHDKTFEIPVDGTVRVVDASGTALIEQPVAAGDIFRACQTKDAPIRDWVKLAVTRARATGVPAVFWLDESRAHDAVLIEKVKQYLPEHDTEGLQIEIMSPEKATAFSLERIRRGEDTISVTGNVLRDYLTDLFPILELGTSAKMLSVVPLMNGGGLFETGAGGSAPKHVQQLVKENYLRWDSLGEFFALAASFEHLATTTGNARAQVLADTLDRATGTFLNEDKSPSRKLGGIDNRGSHFYLAMYWAQELAAQTADAELAEAFTALAKTLTEQEQTIVAELIAVQGSPVEIGGYYQPNVEKASAVMRPSATLNEALATLA
>NZ_CP025394|884712:1006869|907340_907865_+|WP_158702012.1|DBSCAN-SWA
MTLVYAGNQYDRDDAFDRFFAPAAAHVDHQVVGKWTDTARWPHVRFTGRKPFPEIARLHGRALATVLLLPDRYAAVGQLTQRLFEAVLAGCLPLAPDTIRDVHRFVPPQLIVRDGTQVTRVLRELREQSGTAQHARLLADCLERLNLFRLSAQIERLELAIDAAAGATRNRSVA
>NZ_CP025394|884712:1006869|933734_934466_+|WP_104814784.1|DBSCAN-SWA
MAVEIAYETHSTTADNEAGIATGRLADELSELGRRQARELGARRPGHGFAAAFVSDPHRAVQTARIAFRDGPPLSIRTSGCTTATTVIPTEAHSPTSPLNQPGTSTNGSPAARVTARSSGPPTPSATTSFPGGRAAESWQSPARPSGGTLPPGRPSNDMLDTPPAWRPDWPDTLLADWTDSAGCTWTEPLQDWIVPAALSSRSGSGPVMGCCNDPEARIVGAGTHSRQWGQASGSEARGRAVE
>NZ_CP025394|884712:1006869|929860_930886_-|WP_104814782.1|DBSCAN-SWA
MSDDELHGLVERLWSELEAEQPTGDRRLRVAELPVVVESGPLAVAVDHDGHRHVLVPIHTHRKVRSGLDGPVLRLRKLPLEDAETYQTYVDLACLRDDLDDLFTELCVDVLDAVRESPENPVKALYRVIDRWKALFLTQSAPLGPEELAGLFGELTVLNRLLTKDPSAHRLWRGPEGHCHDFLGGSTAVEVKASTSSEGRRPRIHGLDQLEPPENGSLRLAWFRLQRTGANGVGTAFTEVVEEALRLCDDETALLDLLARAGYHRPDAERYRDVTFAVAEERWYGVDGGFPALTGRTLIAAGVPVSVLDVEYTIDLSGEVPNPLTADQIALTIDHMIQESE
>NZ_CP025394|884712:1006869|1003903_1004302_+|WP_104814833.1|DBSCAN-SWA
MIAAYLPTGSWWAIAAATTVFWVAVMLPAAPTRAYRLRYLGLPVLLGALLALRSHGKHFTQQELLSCYALFTFAFPLFVIGRWEEMREYTLDREAQKAGKDVTPTLSRGARVQMYVVTALLVVGTVAILLPG
>NZ_CP025394|884712:1006869|1002741_1003683_-|WP_104820647.1|DBSCAN-SWA
MVKGVTVAAAAVLVGAGVAPGASGAVPGGAEAARLAAYWTAARMAAAVPAEARAGAAGAGRAGRGVPVDGPAPGEIVPPSRSFDGIPQVGTFFWADAGGTGRTCSGSVVHSPGRGLALSAGHCLKGYAGAEAERHLAFVPQYHDGLKPFGVFPVVTDGVYVPQEYYDRGEQAGAAYDFAFAVTGPDPAGRQLEDVVGAVGLLTGSGYAHAPVRLIGYPAGAAKPLDCTSATTAWAPEDPAEPGTFERIACDGFVGGTSGGPMLVAWQGGTAVVGVIGGYHTGGDTPQISYSAYFGAATRALYRAATTVAPPAG
>NZ_CP025394|884712:1006869|909278_910070_-|WP_104820582.1|transposase|DBSCAN-SWA
MSDAEWAVVRPLLPVPGWLRGRGGQPEAYCHRTILDAIRYLVDNGTKWRAMPADFPPWDRVYAFFRRWRDHGLVRELHDRLRRKAREQAGRDPEPSAGVIDSQSVKADAVVGRDSRGFDGGKLINGRKRHAVVDTLGLLLAVMVTAADIGDRAAAQVLLAQVAAAHHRLALVWADGGYTGSLVEYGFTVLALVLAIVKRSDDMRGFVVLPKRWIVERFFAHLMRSRRLVRDFERSTGSAEAMVYWSATMLMTRRLARPRPSRA
>NZ_CP025394|884712:1006869|954451_955300_-|WP_104814797.1|DBSCAN-SWA
MDGKGTPMERIRALDHLTPRDAAKEWGVPKHMIRNAADQIERIRNGSHATFALDRPRCPAPVTSFFGFPCKLPIEVGGTLCALHRKAGGHPGSDAAADALAVVQAHPSWEELRERFWTMDKRALQSERLRLSRELDAGATLTEEDYRLAALLLPSPDPATQGRRALGLPGPNDGVGDVARLRGLGVLLAAADAAVLGLPVTKPDKSASPAATGKRAGPLLYSMAEAAERLGVAASWLRTESVRGRVPYRQIGSHRMFSEEDLEQIVKDAYRPSAGRTRTGRR
>NZ_CP025394|884712:1006869|972869_982430_-|WP_104814811.1|DBSCAN-SWA
MAVELPEPLQWVLLLLAGCRWPEADEDQLREMADHCRKAATELKDATQSSDAAIKRALDGQRGAAAQALTTYWAKYSTGKGTPEDPGYLPGAINALDGMGDMLEQMANSAETAKIQIIAQLGILAFEIATAEAEAPFTAGASLLEVPAMIGVSKAVVSTLLKTLLKEMITMAAKQAAQMAAINLLAQGIELAQGHRKSIDMKEVGQNALGGAVGGASAHLIGKGIGAAGKKLGAEGALNSTAGKMATGAVVGVGADVSTQLITTGKVDPNSLLGSGLSGGAGAGLHAGAAALKGHPDAPKLAEAPHLDSAGAGTRSGPDGPPTFSTSTRSAGDNTYQGPASRSLGSGSGDEGAGNGPGAGADESRVNGLVPFGSPSASASARTPSVDAVSARSLDRSMEGAPDRSLGAVSARSVDRSLGAVSARSVDRSMEGVPDRSASATPEAQLHDVSSVTPETQLRDVASVGRPEQSSVAGEPMTAREQVAQQEPMTAREQVAQREPATLREAAAPQESRGDSPSAQRVEQEPAVPAQEAVATRQEMPTATLQEPMPRQEVGEPALARGGDDLSPAPSATSQHRAAEEPAIRSEVGREELPQQAEPLREPLAEQPGPAGAPLVEHPVEREGAGVSVPMHEQSPVAEVPGEQRAVVAESPAHEQNPVAEVPGEQRAVVPETAPVREQGVVAEVPGEQRAVVTEPVAPVHERQAVVTEPVAPVHEQQAVVAEAPAQQRAAVTEPVAPAHEQRAVVAEAPVEQHTLRAEEVGTESSAVPLQRSGAATVPDLGRVLSGVAHPSGGGDNTSLAGGARVSGAETQPRPGSEQAVPVPGEADPALASGAQNQTAIPPVGGGFVPGPVAGGGGGHGSSSRPASPTPSTPKPSEVRNTRPDSPAGTLRPGPVRSRTDRSASPTRQERPKQDAVPQPERQAAADDRVYEGFREFMDGVDGAGSHLPEYQAEGGLPPAGQEHGQQEPHVEASTHGAPPSSETLGGSKGEGGGEKSAVHLAGQEHGRQEQQESHVEGSTHGAPPSSETLGGSKGEGGGGMSAEHLAGQEHGRQEQQESHVEGSTHGAPPSSEIPGEAGTEKSVEHPAGEGLPPEGEGNVPEPSRRAVTETDFPPAGRRVPVAGDGLCLLHSLAVSSPELVGHGGTGGAGAARRLQSAVEDHFRDLPPEHWPTEVVANYRGNLVARGDLTRSELLDYLPADVRPGYERLPLRDLREIVGEHLTHNAPPPSARERAALLRTARDWERRWLTTEGEMLPAAAAHALGLRLRVLGHDGVPRAVFGPADGRPVTVYHRGNHYDGSEPPPRAPQDPHPPATPAAHQHTNDPAQQKATEKKTTEEKAGAEPTVPKDPAEAESSEQPAKPPAPETPKPEGEGGGGPKPPAGPKRIEGSDLVVGLTEHETAVRDKVLAVLERAVPGDRAAARAFADAHFGPATLRPMVSALSRGETWTAKLEGNGWSGSVKLRGELTESTHLRTEKIEFENGADRTVSTGSQHDVQWQSNIGIQARQTVAGAEPAELAAYHHDRGHGEVNLDLGGMVARSKTSEPADVFKSTMRLELDFGDLRHDHTPVSTGSGGHTETVDLGMTVARPVRAEGDAVGELRTPPQRLRDGRVGGQEIVLDLSPHGGSEGHRPVEGLLDHVDEAARKEFGKDWPALREKVLAEVDFPRLQRDLKSMTAGEPVTVALTDRRGRTIGSVEISARVGDLHQTGTTKETEFNIGTSVQQVRSSAKSRGNAGQLGLANTLRPAPVSMGVGGAGRLGRDRIEISGDSRAAQLTSKSKVPGVRYEGPVHFELSFNGKPDTHPAGTADVRLLVDRADTTPKAAEAGKATETAEAGKATETAKTVETEGTAPPKTQEVAGPPDSVWHGGDDRGGLGETVVVRDVETTAALRAAVDAKGRERFGDDWDAVRGEVLRGFSQPNLAARLTGMTRGEPLEVKVPGKESLVVTATARVESMTFRREDGKAELNTVSETSTFSVDRRLESRTVAATGQFSGTVAKGTPGADLGAVTTGQQRERVGGQGRQADRVYANGKYSAPQVIYGAHLAVDVHFGRPGEKPEGKSEVSAPLHVEVGLDARDTVKTEAPVGEDGAIAFKPPTESAESTEPAAGGRPDGAGREAVELDRPAATHTAPRRMREQQELNASYVVHTLSGADKVRTTVEDAVRSKYGEPSEEVRQRIGATFDRVALKAQLSQLTRGGKITETVSGTTWKAEVTVTARVTDSAYHSTAEKYEFESGTRSSRGQGNVRDRRERLDAGGRFNVRAPFVTVGGGYSHRIDRTYANGVETVGSASNRGKHVEPAVIFDVGAAYDVKVTFKRLGVDDGSHTQQVDTVARVAVPMRDAEPVGGPVERTTTTQPKGFVEGRRLDSSAIVTDIHALPEAGHGKVEGTADGKAEIPPGPRRTLGESVLSQVEAGWKPAASRRTSGPSPTERNPFSSDWAGIHRKLEAELTPDRLQSRLKGMTAGDEIVVRHGRTTVRVGAVLRDRMEHLGDSGTTEFNTGTDVQRSFADTEGTGNSHQGVFGATAAVPVPGAPVSVTAGLTGTGGRGHDHVDVRNTGTGAGSATKAKVPGSAYRGEAELQFTITRRPLVGPSVHQRRTAAIGFETIVETSETRPVPSKPSAEAPKPSAETAGPERPPRTLPAEAPERVSVQVPPERVWDTGLRDTDVLRHLGDVGGVQDLVRLRGPEYFGKKTWEEMQPLVGSVTSHSHLSALFGTATQGSEVAASIPSKRVTLAGGKGVEVGVKIVSLEHGDTDKAVELSPSNNTSSGTTHAELVSKNAGAQGQVGARVTAGITSHNPAITGGTQRLWREGGTHGDSGQVVNNAKYPTPMARYSGHAEVEVTLFDGNRNPVKEKGVVPFTVDIPLSETTAVDLPGDHYLAFTEDHHSGELRSGEGAGLLEDVHQVVSGGGHPFDQATATPAEREQLMGTARVGRAAYGSGFTAGTAAGEAHIQAAHRLVELSGGSSTATSALLGDLLGKPAGTPLKGEEVRQVLDYVERKQAEGPVTLDDLVAGAQDGWPEQDPYQVHREAWTDHGPANELVTAAMATASDAARPLLQSGLPTVGRLHLTVSGEGPDLPLRQEFELSGDPVEQIRSIEQSTYLKPGTRPSEVSVRLASPPGAAQGWDYRLTARPDGSRELTLRHRRGAEGEQPDEQAGAAAAASITAAGRFAAGRSAARVE
>NZ_CP025394|884712:1006869|923884_924949_-|WP_104820642.1|DBSCAN-SWA
MAAKALDIPVVMGIEWDEDACTTRRAAGLPTETGDVRKYNPSQFPEADVLVGGPPCQTFTVAGNGEGRAALEQVLEFAKRYAAVQLDRQAEEFAAIREDLGQLSDERTGLVLEPLRWALEALAGGKPYQVIVLEQVPAVLPVWRAFGEILESKGYKVAEPEVLHTEEFGVPQTRRRAILIARWAGDGARFQADPKLPEPSHRCYRKGIHRHQGDSSRLPWATMQEALGRTDCFEVVSNYGTGGDPRARGRRRHDEPSATVTGKASRNKLVWGEQHLGTFSLPELGMLQTFSRDYPWRRRNGDDVEGVDAPGVRSVIAQQIGNAVPPRLGMHVLAAALGIKREDLESALKLQFDY
>NZ_CP025394|884712:1006869|987420_987861_+|WP_104814816.1|DBSCAN-SWA
MPSHPPARHLLRAKDLVDARYADPLTVADLAAAAGLSPAHFSRAFRQAFGESPHAYLLTRRLERAAALLRHTDRPIATVCLDVGLNSLGSFTTSFTRMYGLAPAAYRAACPPAADHAVVPSCVRRAYGRPQHRTFREDGADPPGIA
>NZ_CP025394|884712:1006869|901809_902481_+|WP_104814767.1|DBSCAN-SWA
MTTPIELTVDQVVDRLAALDGSLPAADGVRVFNDMYLTVTRLVRDHLPGAYFADPAGMARLDAIFAARFLAAVDAVAAGADPSPCWRPLFELRSHPGIEPIQYALAGMNAHIEYDLPAAVLAYCQAAGHTPTQVEADYHRINDLLAQVEAQVRRQLEPTALRPADPLLHVIGVWSVDRAREAAWASVLSLWELRRIPPAARAVQTALAQSVGMVSRALLTPLG
>NZ_CP025394|884712:1006869|997747_998575_-|WP_104814827.1|DBSCAN-SWA
MSTATATTGGSHVLTHAKVMLRRNLRHLQRYPSLTLMVTLMPIVFLLLFVYVFGGTLGSGLGAGTPAGVHGGRAAYAAYVAPAIILMAVAAAAQGTAIAVAQDMTEGIIARFRTMAVARSSVLTGHVVAATVQTMTGVVVVTLAAIGVGFRPHANPAEWLAAFGVVLLLTFAVTWLCVGLGLSAKSVETASNSPMFLILLPFLGSGFVPTDSLPTGLRWFAEYQPFTPVTETLRGLLTGTAIGDNLVITLAWCVGVAAVSYVWSRRLYEREPERA
>NZ_CP025394|884712:1006869|905513_905957_-|WP_104814769.1|DBSCAN-SWA
MNDMIKALEALTDREPNRRDVAADSLGDLLRGTALDTDAAHLVVGRLVSLAVNEPETKVRESALNSISEAFNHHRLPLDLVEPLATAMTTMEPELLEHALYILGATHDPRALPLIEPFLHHLDPQMREDARLAAAEIAAPEGPTHNS
>NZ_CP025394|884712:1006869|947358_948177_-|WP_104814791.1|DBSCAN-SWA
MPASSFGVMPSSSAIRGRAVALLLFEALAAEAVRRGHQVREKPVAERHRSRAYYYNGRSHPSSYSRREGELDIVIDGFAYTVTIQQEAPQATDPEKAERLSLELPHYRATRQCTWHDRKSWSLEELLPTILEELQQRAVDDRQGAIDEERAKAERRVGWETAMAAAKEQALQEQYAKQLRQQAHQWRESTELRTYCDALEERLASSQAVDDAADRASARTWLAWAREYVRTIDPLDTLPTMPRPGKVELQELKPFLNGWSPYGPENSRSSWH
>NZ_CP025394|884712:1006869|970333_970678_+|WP_104814808.1|DBSCAN-SWA
MRHFHQFGPHHGGWVWVLSGITMILLCLVLIAVLVTLVRFWSHRSGPGAQRHYGGPKGPGWQQHGGAPGWQPPAPPQDPAKLLADRLARGEIDPEDYRQRLAALQQPPPGAPGL
>NZ_CP025394|884712:1006869|994776_995262_+|WP_158702024.1|DBSCAN-SWA
MTKPGAPMLRVRTSLPQRAVLTTVAAVLALLGLGGVLAGTAGAAVGGGSALLVAAVLALRSLRSGIEADLDGITSRTVERTQRLRWCEISSIQPGDARSASPVPATALVATTTAGRRLVLGGLVGPATRRNSVRLQLLRAELDRLAARHHRECATCSATPS
>NZ_CP025394|884712:1006869|1001188_1001758_-|WP_104814831.1|DBSCAN-SWA
MKQEDGELDTLVRKRIRGLRVAMGLSLDDLAARCFLSPSTLSRIETGHRRIGLDQLAAIARALDTTIDHLVEPADDSDVVIRPQRDEARGITRWMLGRDPSTTVAKLRLTRPAPTGTSLLKVHPGRDWFTVLSGTVELALGDRRILVETGQAAEFSTMIPHAFGAHGGPAELLAILDHEGGRSHLRLPE
>NZ_CP025394|884712:1006869|925060_926104_-|WP_104820643.1|DBSCAN-SWA
MRRFTSLEICAGAGAQALGLERAGFDPVMLIDRNPKACATIRLNRPGWDVRCLDIVDFDPLKHPGALHVDLLTGGLPRIKSAGAVRRTDDTEARQVLTAALRLVTLVRPKALLLENLADIVDVRDFATDRAWIESELARAGYRSHWAVLDAVDFGVPQNRRSGFLVALPGAYDLAFSWPQPTGDPAPTVGEVLRDSMAANGWDGAEAWSARADRPAPALVGGSENRGGADLGPTGSKRAWAALGVDGNSLADEPPSVGFPVAAHPKLTVRQAATIQAIPDDWSLAGGKTSEYRQVGHALPPPLAEAVGRALAHALGVGEADPDRLAHVGHLVRGPHLAGYDRGRSSS
>NZ_CP025394|884712:1006869|995350_995986_+|WP_158702025.1|DBSCAN-SWA
MPRTAATLTWRLLALLLLFTAAVAGALAVWSLAAPVPSLPLAPPLLTGLAALVLGTFCALIGWPQDGWQVVLVSLPLMALLWIAALTADFAYTSVHNWDRTPLAVTATLTDCRVDAVHGDGDSGRTEKDSCVYHYTVLGRTHTERHDSPGAEHDGNQLQIWLNPTTGEIGEHSLTNVVLISALALLAATLALLGAWTAARAALGHPEEEAG
>NZ_CP025394|884712:1006869|919651_920827_+|WP_158702015.1|DBSCAN-SWA
MSIFDSRDQWDIGPDGHLVAAQMSMKLHPGSPSRVGLWTIDDTAGARPVGTIDLPDTLQQVTFVNAITLLTVDHSGRPQLWNISDPSHPIAGTALTTADFTTYPTGLGDFIISTAVTVDKDLATVQGGGKLQLWRVNGSSATEAGSLPAPDPADVAGLLNNHQAVVAAKDGFTWWDVTDPDHPVHVADTPLGGGNKGNVHGSGSVVAAVLGFPAVKNTLFLLKFPDSKSGTAVQLTDNAGGEVALSDDQHFLASDGSGANTVNLWDVRDPAHPRATAAVTTKPGVQGMAFNAGDTLMATWSAAGVQLWSLRDSSSPALIVSIPTSYSGTPITTFTPNSAWLAVDTSSSIRFIDTNPNALATRLCSYTGKAMTPQQWAHATQGLPYQPVCNA
>NZ_CP025394|884712:1006869|953602_954364_-|WP_104814796.1|DBSCAN-SWA
MHRWDPLNPGQLALLQRIASGDALDSPSDSKSRTTGYALRNLGLVAIDRRGGRWVAQITDAGRYYLEHGQHPDHPARLADSHPAAPQKASGSATQGAAAAAPKPPTVKPKNPARSGPSQIRLPARRKAEATELVARLVAENKVIVTAPSDEAIATWRRLIEYAKRHQLLPVGKRIETQRHWNAGRDFEIRLVDGATESRRQGPQPDLAPVPVPSQLRAPNRVVAALRDDTSNAGDLWISADRHAEGVPSRMIL
>NZ_CP025394|884712:1006869|899024_899996_-|WP_158702010.1|DBSCAN-SWA
MPTRREADLWLLLGAGLSGPFTRRITAALAGEFGDRFAVVRSAELVMGAGRGGLSLHGSDGGEVTAPQVVYGRVRTPGAGAGREIALLRHLESMGSLVLNPADAVLACQDKFWQLQRLVAAGLAVPESRMGGGTPLHEVTAASLGTPCVVKAVRGHRGEQVFLAPDPAALRALHGRFGEDTASLLQEYIGHSHGRDLRVVVVDGHAAAAGVRTAAEGEFRSNLALGGTLAPCPGRYPEGEELAVRAAAAMGLAVAGVDLLFAPGGGFVVCEVNANVSCRPELAGVPAALVAAFRARLRSTGGPLPASRRPEEPVRAHPTSAES
>NZ_CP025394|884712:1006869|998608_999550_-|WP_104814828.1|DBSCAN-SWA
MSATATLTDTAISARGLRKSFGEKTVLDGIDLTVRQGTVLALLGPNGAGKTTAVHLLTTYLRPDAGEIRIADQDPARDAQAVRRSIGVTGQFSAVDGYLTGRENLLLMADLHLLPKAEGRRRAEELLARFELAEAADKPASTYSGGMKRKLDLAMTLVGRPAVIFLDEPTTGLDPRSRRTMWEIIRGLVAEGTTILLTTQYLEEADQLAHRVAVLDGGRIVAEGTPAELKARIPGGHLELTFADRAALVAAAALLQPTGRDEDALTLQLAGDGRVVTLRAVLRRLEEAAIEVEALTVHTPDLDDVFFALTSRN
>NZ_CP025394|884712:1006869|989025_989751_-|WP_158702023.1|DBSCAN-SWA
MTGPRPVQLQVSGHGVEVRVSAPASGPAVVHGIAFRVMGRRPLGTAPGKVSVLVTGTVNIPMPQIRVWLDEPDQMTPGPVPLSLPDTVPAGESRVYRLTAHTREHDVEWQLGVEVSTGGDPVWRGYPIRTTAETGWRIFHPDRPMTENANSHREPDRPEIAAGTEATHRAGAEQGDHAAMYRLAVSLAERGELAEAQRWFHTCAERGDTEAAAAVASILELRGEAAAAEEWHRRAAGPGGS
>NZ_CP025394|884712:1006869|993943_994726_+|WP_104820646.1|DBSCAN-SWA
MSTPSPSEVLRRVASVGPYFAVGLGAPGEPAPGGFTPIRELYAPGGPLTVRVAAATGQLRTSETRVAVSVLHLGLAARLWSVALGAAALGPGLPELGPDTLHHRWPADGPLELWLPAPEPEPAAGHAPDLATAVHRTVIGGHLTPLHDTLRAITPIAPRLLWGNAASALTGSLQILHTRIAPTHPAAAATALRVTQQLLAATPLLGTGVLAPDEFSPPSAPQRFRRSTCCLYYRLPAGGTCGDCVFGTRPPRPRSATPTI
>NZ_CP025394|884712:1006869|916463_919727_+|WP_158702014.1|DBSCAN-SWA
MTGVDAAALAVPEALEAALVRIYGQSGAPVGVGFLISDRLVLTCAHVVSTALGLPIAQVPPPDAWLALDAPMAGGPESPERERGSVRVWGPAQPVGADLAVLDLEHAPVGTRPAWLVDTQGQQLWGHEARVFGLPQGRSAGVWHQGVLRARQADGWTQIDLAGEGYRVSPGFSGSAVWDQELGGVVGLMAAAETGNPPVSYMLPASLLFSCWPELRSHSLPPSPFRGLSPFLEGDAGLFFGRDGDADTLASVTVAERWTTVVGPSGCGKSSLAMAGVGPRRRRAGDCTVVVRFAWYDSPLRALAAALLPLLGAEPGDEAERFDRITDLAAHLGAHGVRESVFRILERHGASRLLVIVDQLEELLTHDDDGIGQLAEVLCGPATPAELAVLATLRADLLDTALTHPVLGPVVSRRVHALEPMRPEQLSEVVSRPVDTVPGVFYEEALAERILADAGADPGVLPLLGFTLDLLWRRRDGWLITHQKYARLGGVAGALGRYADEVWEAVVPAREADVAERLLTRLVRMPLGAAAPVRRAVHRSEVDAAEWAVAERLAQRRLLVIQGRGGTETAELAHEALITAWARTRDLTTADRAFLAWRESAQTDLDRWEHAKRPADLLPTRTALAAARQWLPARSGELSAALRDFLDRGRRRNRRRRGTLTSVVAAVCALLLAAAALGVSAQRNHRDAAHNAAINRANTLATDAAALASSDPGLAAQLAVAAFRSAPTQAAVDQLYASIAGPLDQVLASTGSPVVQVVAQAHGPLVAASSESGSVRVWDTGHLDTPHLVSTLPSTKGGAIALAPRAPQLAALCPDQDGLCLISLSDPQHPARLGQLPTPHPWPSGELTLTSLAFNPDGTLLAGATDAGSSLLWSTTDPTHPSLLSTLPGKGSGKKIGAVAFSPDGRTLAATNQDGTTQLWNLTTPAKPAPAAAIPTGYQSLAFSPDGAWLAGAGDLRLDLWKTSDPSTPIEADPLRTVGDLMSVSFSPNGGRIAWGGTGINDSNSAMCLTSVQYISPDKSSRSAPRPASTATPSRTPPAVRSSPAEPTEPYASGVTPRPRRRACQYLTAATSGTSAPTATWWQPRCP
>NZ_CP025394|884712:1006869|897817_899053_-|WP_104814764.1|DBSCAN-SWA
MRIPRPPSRRRPPSSPRFRLFALGQTVSNTGTWMQKVAQDWLALHLSHGSGTVLGIITALQFLPLLLLGPYGGVLVDRYCTRRILLLSQAVMAALALIPALLVATGTARLDAVYGLALALGLTMTVDKPALQAYLAESVAPGQLVSALAVNSAVLNLARMAGPALAGPLILAFGPGPAFLANALSYLVVIACLLRADPGAVRPAPAVARAKRQVREGLAYVRGHRPIMLTLVLVAVVAAFGMNFQITTALMITQVYRAPAAVFGLGNTALAAGSVIGSLLAIRHPRTGGRQLAAAALAFGTLEAGCALMPGCIGFLVLLVPTGTAMLVFLTAAKARLQLEAGEGMRGRVTSLYLLATLGTTPLVAPVIGWIAQDAGPRAALALGGTVSAVAAVTIGLLHPRPAGPAAMAGC
>NZ_CP025394|884712:1006869|892446_894276_-|WP_158702009.1|DBSCAN-SWA
MLVGLSPAQESMWLDQLLHPESVNGGIFSVLVRGPVTAGQLRAACLAVCAQSPQLRGLVVPGEGGGPARIAVHPAERVLRFETVAVPAPPGAELTVARQWHRTHRLRPWRLTEQPPIAFALLDHGGQRRTLVVAVHHIAFDGRSKFVFARRFLQALGELRSPAGLREREPVALPEHPSIDAEAAAVVEHWLAADLPHLPGLVLPRRESPLPAGGRVVEPTPRFELPAETCARLAALTGAAGVSFFTGLVAGVAARLHEYGNTRFVLGIPADTSEPGTREQIGLQVNVVPCLLDIPAGASFTDLLAVSGRALALVQRYRRVPFGWVLRQLRQRHGVDVTRGAFDGVGVSYPRVVRELGEVPGLACEWDFFAPNSTQSFDLTLQLRREGGAAYGRLDHSTLALDGAAAGRFTAGYARLLAALTAEPGRPVAELFEAGPEVVVPAGVAGVAVRDEVLGVLGYGLRVGGEEVLVGGVAGRRYRVVTAEGRGLPQGVPGLLAFAGDGRVGRRRAWIDSAGRVRLLGTAGQLRDWMGRRLDLAEAEAALAGLPGVRSAAVGLTGEAGALRATVTLETAGTDLRAWRRAVRGVWPSGWPQVAEVRLVTGPAGGHRP
>NZ_CP025394|884712:1006869|999546_1000437_-|WP_104814829.1|DBSCAN-SWA
MSRSTFSTSSPIVVLLDLYVADVRIRATDGADTVVEVSPTDPAKPSDVKAAEATRVEYDEVTRTLTVVTRKPRNRFVNFSKRPESIDVVLTLPSDSDVRGEVELGDYLAEGVLGSVQLKSGLGAVRLGETGDLTVRTSIGEVSVDGVSGSAQVHSSAGEVRIGVVDGGADVSSGNGTVRIGVVTGTAKVKVSNGAVSVDRALSDITATNSNGEVRIGEVVRGKVVAASKNGRVDVGVRDGSAAWLELDTKVGRVYNDLAAAEAPEAGEPVDKVEVHAETKLGDIVIRRTARLEEQA
>NZ_CP025394|884712:1006869|985401_986196_-|WP_104814814.1|bacteriocin|DBSCAN-SWA
MDNLHRHLAPISTAAWAEIEEETRRTFKLHCAGRHVVDTAGPEGPDFAAVGTGHLRPVPSPQPEVLTRAHRVRPVVELRVPFTLGREAVDDVERGSADSDWEPAKAAARTMALTEDRIIFEGWPDAAVEGIRTASDNEAIPLPPEVADYPDAVSRALTALRLAGVDGPYALLLGADAYTAVNETSDHGYPVRQHIARVLDGPIVWAPALSGGVVLSTRGGDFELHLGQDLSIGYLAHDERTVQLYLQQSLTFGLHSPEAAVSLT
>NZ_CP025394|884712:1006869|949206_949977_+|WP_104814792.1|DBSCAN-SWA
MSELTGNRIRTTAGKLGLSHLAETINEFTRRADEAKMGYVDFLDLVLSEELAVRDDRRFRQGLRLSRLPHHKTLDEYDFSFQPDLDPRKVKDLVTLSFVETKANAALLGPPGVGKTHIAVALAVAACRAGYSIYFTSLDDMVRNLKAAEAAGRLTNKLGTYLRPSVLVVDEVGYQPLERAEANLVFQVISKRYEKGSIILTSNKTFSEWGQVFGDEVLATAILDRLLHHCEVIAINGPSYRLKNRLKAIARETEVA
>NZ_CP025394|884712:1006869|937967_938807_+|WP_104814788.1|transposase|DBSCAN-SWA
MTDRRPYPSDLSDARWALVEPTLSAWRRARTERALAFGRPPEHELRDLLDAILYVDRTGIPWRYLPHDYPPWETVYAYFARWQKEGVFEQLNGLLRRLVRAAEGRDPEPTACIIDSQSVKTSTNVPAATQGIDVGKKIAGRKRNIVTDTIGLLLMVLVTAASVQDGTAGRQLLTVVATNHPTVHKAWADMGYKNAVVEHGATLGIDVEIVRRDPATRGFVVQPRRWVVERTLGWLMNHRRLARDYEALPARSEAMIHVAMINLMTRRLTGESTPTWRGT
>NZ_CP025394|884712:1006869|922428_923580_-|WP_104814780.1|DBSCAN-SWA
MAKITAAAGVRRPAVMIRSSPWKAGSEQTPWHDVFDLDNGHVRYFGDHKFDTAKPLGSTTGNAALLEVFDGHQAPTAAGRAAAAPLLLFRSVSRNGKVKGHVEFCGVGLIERAERVVQWAGRARTTFTNYVFDLAVIDLAAEGDKLDWEWITARRVASRSDAEVLELAPTAWREWVKRGHSVLPRVRRRVARSRVIKVRDQRPASGSTAETDLEAVYRRFDGDKHAFEALASAVAARVMRASGHSYTEGWLTRRSGDGGADFVGRLDLGSGLAGTKLVVLGQAKCIKPDSLVSAEQIARVVARLRRGWIGVYVTTGSYSEPAQLEMVEDQYPVVLINGQDLVKELREIALEDHGGDLSGCVEHLLNSRPLEVLNRRPEEILLG
>NZ_CP025394|884712:1006869|905953_907204_-|WP_104814770.1|transposase|DBSCAN-SWA
MLSVVTDDGSTQSGSLIDEIVREGARRMLAAALEAEVNQYIAELAAETDGRGRRLVVRNGHHRPRTVVTAAGPVEVRAPRVNDRRVDHETGERKRFSSKILAPWCRKFPKISEVLPLLYLHGLSSGDFVPALEQFLGGTAGLSPATVTRLTKQWSEDHAAFQDRDLSDRDFVYVWADGVHPKVRLGQAHSCVLVLLGVRLDGTKELIAIAEGLRESTESWADLLRDCRRRGMRAPELVVGDGAMGLWRALAEVFPAARPQRCWVHKPRNVTNCLPKSAQPGATKAMQEIYNAESRAHAEKAIEAFAKTYGAKFPKAVAKITDDRDELLAFYAFPAEHWIHLRTTNPIESTFSTVKLRTKVTRGAGSPTAALAMVFKLVESAQARWRAITGAHLVSLVRAGARFENGVLAERSEVAA
>NZ_CP025394|884712:1006869|989747_990452_-|WP_104814820.1|DBSCAN-SWA
MHGETGGLDGSNDRRPAGEWLVRNEFSGVAREVVQAGSIGELHVHSSPPRLPPAASPLALTSVVVATEYVTPGGWDEAVPCSGGAVRIHAEACEDRAVLLRALRIVVVARRPPVEGVELPTAGVPEVRRYTVDLDRDPPRLAGPEFLYTVTPDDPEVFELSVRCERFEVEWRAEVDWICGGRTGTSVADLAGEPFRFTAAPSSSSKIGGVVPWTGPSLKCPASASSGWSTRRAR
>NZ_CP025394|884712:1006869|988457_989003_+|WP_104814818.1|DBSCAN-SWA
MQDNDDTPQPDGGDGQRGTPAPDRRRRRVLLLAGAIGALLLAGATTLALVARDQPVATATPTAPPRSSTSPTPTLTPALPAAPPPPSPTPTATPSEPPTTTPPPPEPPAPTRTHTPTTTPRPTHPASNPSPINPRPTITYTGPTSCPPGYQLVHFPTGAECITVQQGTPIPPPGASVPPTG
>NZ_CP025394|884712:1006869|910401_910959_+|WP_158702013.1|DBSCAN-SWA
MLGDAHGTAWTYDLRGARLDRPRALADGAGLPDYVSPRRRALERRLLQGFISDREALDLLLGVLGRTADGPAAFYKDANPRNVLITASTVYTVDVDDLTLAPFGYDLAKLIHTLALSHGPLPPQAVRDAVQHYNTAAGRHHRQLGYLTTTQLDDFLLLHRALTAPYTDRDHYRNGRPQPLTQEAQ
>NZ_CP025394|884712:1006869|970796_972278_+|WP_104814809.1|DBSCAN-SWA
MTEQDTPEEQIEYGPGIAPERLELFLAVLAELDELEVDHPDAIKVRMAVGGIFRTLKQRRRQETRARKTANDRAVTAATATGAPGRIDDETAGAFGLTTATTTEIAGILERPRSCYTCKTRYVQVDAFYHQLCPPCAKDNRSRRDASVDLSGRRALLTGGRAKIGMYIALRLLRDGAHTTITTRFPKDAIRRFKAMPDSAEWLHRLKIVGIDLRDPAQVVALADSVAAEGPLDILINNAAQTVRRSPQAYSELVAGEQAPLPAGELPVSEVFGSFGSGSVERPMLPGQPSGTHEALTADDVAALALVTGSASPARIEAGTAIDAGGLVPDLHDTNTWVQTVGEVDPVELLEVQLCNVTAPFVLVSRLRPAMAASTARRKYVVNVSAMEGQFSRAYKGAGHPHTNMAKAALNMLTRTSAKEMLETDGILMTAVDTGWITDERPHPDKMRLAEEGFHAPLDLVDGAARVYDPIVQGELGQDLYGCFLKDFKPSAW
>NZ_CP025394|884712:1006869|972328_972781_+|WP_104814810.1|DBSCAN-SWA
MPTPPLLGAGVIVPSTDGRHVLIGRRTTPGEPPTWSLPGGKVDQPGESFEQAAARELAEETGLQLPAAEMRVLAMLLDHATGRARLTAAVLAPPSDAPARNLEPHNCAGWERVPVGALPTPMFLPSGLVLASWLPSAPFPLDGAFRYPVG
>NZ_CP025394|884712:1006869|887002_888325_-|WP_104820640.1|DBSCAN-SWA
MKSKHAPAAAGTPDPYFPTSGDHRYRVHRYELTLDYQPGPNRLGGKARLSAVANAALEEFALDLAEFRIGRVLVDGKAAARYTHRGGKLRIRPAKALAAGAAFTVEVHYAGNPRPVRSPWGGLGWEELTEGALVASQPIGAPSWFPCNDRPADKATYQIEVTTPSPFTVLAGGRLLTRTTRASSTTWVYEQSAPTSPYLVTVSIGHYRPVPVAARPAVPQTGYVPDRLVPAFTRDFARQPEMMAYFGEVFGPYPFGEYAVVIADEELDVPVEAQGVATFGTNHLGGGWERERLIAHELAHQWFGNSVTIADWRHIWLNEGFAKYAEWLWSEHAGGPVAASHALAAHRLLAGLPQDLVLADPGRKLMFDDRLYQRGGLAVHALRLALGEQPFFAMLRGWAELNRHGVVGTADLVAHAARYTATPLGPLFEAWLERPELPQL
>NZ_CP025394|884712:1006869|987952_988372_+|WP_104814817.1|DBSCAN-SWA
MIKIATAQLWVHDQEEALAFYTQQVGMEVRSDVSLPEMGGFRWLTVGPTGQPDVAIVLMAIPGPPILDAETAAQVRELTAKGAAGTIFLTTEDCDGTYAELSARGVEFNEKPTDQPYGRDCSFRDPSGNNIRLAQLSPM
>NZ_CP025394|884712:1006869|907958_908465_+|WP_104814772.1|DBSCAN-SWA
MKKVAVVGCSGSGKSHVARALGGILDAPVTHLDAVFYDEDWNELPKNTFAQAQRDLVAQPRWVIDGNYNSTLPIRLEACDTVVFVDVSTLACLWGLLSRQLRHGSGQKGNGVHNRVHWGLLRYVAGYRRTMRPRVLAKIDEYAVHAEVVRLSSRRRTRRWLREVQRST
>NZ_CP025394|884712:1006869|961617_962679_+|WP_104814801.1|DBSCAN-SWA
MPAKITVAERERLRAAFADPGEFATSPLYRALCQVVATDDALLELAGRGRPGQYPTFLFLGAVHQLLLEGTEHPLAGYFPSVTTDPAPAAEAGPALRDFCAVHEGRLAELISTRLVQTNQVQRALGLRIGLATVAERTAQPVHLIEVGTSAGLNLRFDRYGYHLGGRSYGDPGSPVQLRAELHGTGKLPDLDALPALASVLGVDLAPVDLTDPAARAWLRALIWPEHHDQRALLTASLDLVAADPPAVLAGDAIDLLPGLARTLPPGEPRVVYHSATRMHVPEARLAAFDAAIAALGETGPLWWLQVEDAPDPDPRPAPVLRHGAALRLRTPEGTAETLAVVEGHLRWVETIS
>NZ_CP025394|884712:1006869|964415_964859_+|WP_104814804.1|DBSCAN-SWA
MPLEGEYQPSPMQWIREQVELYESSGGTQGTTLRDTGLPVVMVTVRGARSGRLHKVPLMRVEHGGCYAAVASKGGFPRHPDWYFNLRAHPEVDLQDGPALRAMTARELAGEERARWWERAVAAYPPYAEYQAKTARVIPVFLLEPER
>NZ_CP025394|884712:1006869|902555_904022_-|WP_104814768.1|DBSCAN-SWA
MRFLNPQTGTIDDRYSGPYDLTYDDVFMVPSRSAVGSRQGVDLSSNDGTGTTIPLVVANMTAIAGRRMAETVARRGGLVAIPQDIPTEVITEVIGWVKQRHLVHDTALTLTPGDTVADALSLLPKRAHNALVVVDAAGKPVGVVTDSDCQGVDRFTSLADVMSRDLLLLEEGIDPRVAFDKLNEAHRKLAPVVDAHGKLVGILTRKNALRATLYTPAVDANGRLRIAATVGINGDVAGKAAALIGAGADVLVVDTAHGHQESMISALRAVRSLDPQIPIVAGNVVSAAGVRDLVEAGADILKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAAARELGKHVWADGGVRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLQSTADGRQYKESFGMASKRAVSNRTSAESAYDRARKALFEEGISHSRMFLDPARPGVEDLIDSVIAGVRSSCTYAGAENLEDFHRKAIVGIQSAAGYAEGKPLHSSWA
>NZ_CP025394|884712:1006869|963526_964225_-|WP_104814803.1|DBSCAN-SWA
MGPVTLITGGSSGIGAATARGLLEQGHRVAVTGRDADRLAAFAASAGAGERLLTIGGDAADEHHVAAAVGRVVDSWGRLDTVIANAGFSLPGTLEDHEAEAMRAMVLTNVLGPALLVQQTLPHLRRSKGRIVVVGSIAGIRNTPGNMYSVTKWAAHALVENVRLLVAKDGIGVTLVAPGVVDTPFWDERGGCPDPAQTLTPEQVAATILYAVNQPEGVDLSHLVVRPAGQLG
>NZ_CP025394|884712:1006869|926982_927399_-|WP_104820644.1|DBSCAN-SWA
MAVIDFSRTSFPDEAAWHLRISGGLESATMGSLLLLVNERNTVTTAAFENAGKPRQVDRVVLSAVYADAARIMIEHALGNDDFTEDADFPDGSLGATLQSLFDRLFPDQSITDVRLRQRQSPALFASDLQAAVKIFEV
>NZ_CP025394|884712:1006869|927872_929864_-|WP_104814781.1|DBSCAN-SWA
MTAPRWFSQPYPPLGGPAAEGIRNQLGRPELDLLTILVRESAQNSWDARLIPSPAPVDYRIDMWTVGPAHSGAWRELLLDGAPAGAEDFPLRDTLRRGAARVLVVSDRGTRGLGGPTRADDPVGPDRDFVSFIRNVGAPRDTALGGGTYGFGKGIFYLVSRAGTILVHSRCRTPKGGYETRLIGCTLWKSYVAAGSEGREYTGRHWWGDTSGDVVEPLVGPVAEATAQRLGLRPFGPEETGTTIVVIDPNLDGLEPAAAAEYLADTIAWHLWPKMISTPGRPAAMRFSVTCDGVEFPVPDPRETRPLNMFVAAYEAMIGPDGTDLECKSPKRHLGRLGLVKRIMPPVEPTRASRMLDIEDLVHHVCLMRPAELVVTYRRGPKPPSANQGYAGVFRADEAMDEVYAKAEPPTHDAWNPQSLDRPESTFVQTTFRRINESLEGLLSLGGVTRPGASHVALGAASSRFSGLVGGAWGIGGATAFSKPGSTAVRAFKRKVDGEERSGFDPGSVPHEAPSDTATPGPYGVGTPGDPRPGQQALADAQPYGAGAAMRRRPRVQYVGDPYYDDRGDDSVLVQEFRLPVPGPQRVRIDLAVTLPGSGGRETDPPVGASMPVLLGWEDGDGRLHTGDACVVEGGESVWRALVRPAPDTMTEIDVKVEAVKAR
>NZ_CP025394|884712:1006869|968502_968907_+|WP_158702022.1|DBSCAN-SWA
MSSDPRTRDYVARQTAAGRTKKEIIRLLKRALVREIFRCPTTTVAVPETADLRPARQAKNIPLAAVAHHFGVWPAVISTSNAAPAATTSSQPPTATGSPPINDRPRHNRDASPAEIEEHSAGDRDAARPRDLRP
>NZ_CP025394|884712:1006869|913513_914278_+|WP_104814776.1|DBSCAN-SWA
MPSTETQLPTPNTNRHIAVIPCRWGASRFPGKPIADLAGKPLLWHVYQRCLQATTITHTVVATDDQRITTVCEDHGIPWIMTGIHPTGTDRVAECAERLDADAYINVQGDEPFIEPAAIDSVSTALASLPPGVLAVKACSRLTDPATVQDHNVVKVVTGNDHRALMFSRLPIPYPKSDRPTYLRQLGLYGFTPAGLGIFRALPQGSLERAEGVEMLRFLEHSHPVQMVLTHDSGTAVDTPEDLERAEAQLLSQR
>NZ_CP025394|884712:1006869|921137_922022_-|WP_104820641.1|transposase|DBSCAN-SWA
MCVCSCKPSYDSSLTDAQWAMIEPLLPGRDPRRGGRPLKFPRRLVVDTVLYVLVSGCAWRLVPHDLAPWDAAYRWFRAWSADGTWDRVHDVLRDRVRVADGRDPQPSAAVPDSQSVRSHQGGEAIGYDAGKRVRGRKRHLLVDSCGLVLKAVVHSASVQERAGAKLVLAGIRGLFPRVGLVWVDGGYVNAIDAGLVGWAAAHEDLTVVAVPRNADVKGFQVLPRRWVVERTFSWLGRCRRLARDYERKTAHAEAMIKVAMIRLMAARLAGEEVEPRGPIETEAARRLADDLKNE
>NZ_CP025394|884712:1006869|991308_992130_-|WP_104814822.1|DBSCAN-SWA
MRSRFPLLWLALHRRRRMLVALLLAMVVFEAVIVAVATAVPPGQVFGGGGRTPPGAFKAFSGSTGDVSIASYPGLLGAGLVHPFWIALQLTAVASLAAAAVAADVEQGTIELLVTRPVTRRRLLAERTAALLLVSLVLNAAATAVIAVGVGSSARLHAAVPLSGVFAAGLLGFAFTLALTGPALAVSAVGRRRAQVVGVTIALGAVGFAVNFAALAWSKAAPLRFVSPFHYYVPGDALAHGAVPWGSFAVLVGVGLAGLVTAFLLLERRDLAP
>NZ_CP025394|884712:1006869|941639_944663_+|WP_104814789.1|DBSCAN-SWA
MANFRTSARTVDMLGRQQIAGIPTAINELFKNSYDAYATTVVVDWLRDREFLVVRDDGIGMSHRDFLERWLTIGTDSKTAGGRLEALPIPPDARRRPVMGEKGIGRLAIAALGAQTLVLSRRREDPGQTSGEAPVVAALIPWKLFEMPGITLDDIEIPVLKVAPPDALSNETINRLTSALGDTLHRLHGMADQEFLDVIQADLTRLREFDLSSLRRLPGPQIGAPGSHGTVFIVSPTDESLPIEVDGDRGRPPGEQASQLVKLLTGFSDTMSRGHREPEMRTSFVVRRDSGEAIDLIDGDEFFTDRDFRESDHEFVGEFDEYGTFRGEVSIYQQNPVEHVVPWPAGKGSQTQCGPFKIRFGYVHAELRHSSLSPDVHAQINRKLNKVAGLYVYRDGVRILPYGSSDIDYLGIEERRSRNAGYYFFSYRRMFGAIEISATANARLQEKAGREGFRENVAYRQFQAILINFITQLAADFFRSSSDMGQEFLSKRDVLERTEQIRRKRDKVAGSEREAFRHALQKVLGEFAENEPQNRALDIVRSVGLQLSDLDPSSPSTLDEALAIEKSAELEFRKIGERYTVERPRGIGLDRETSRDWSTYERELQFFERGFLASAASDVRGKVAATTSAAVPLNVLNQRVRQQGQRMLDGNLNVWIQGVQELPRDADAVALQVLERVRAAVNSASRRAKDLADEMSAVADSLDQVEIFELRQRMLDELDAELDRQQKSLAPIRAYLSSFEALLSGNDELGDQMEAVEEEVLALRNQVDTDLELTQLGRAIELINHEFASSIKAVRRNLRALRPWGNRNPKLGEIERELAAAFEHLDNYLALFTPLQRRLYRKPTQIRGAQIEQFLMDLFGERLRRHDVVLTATDAFSRFAFSGYPSTFYPVFVNLVDNAIFWLSDRPQPRIIELDETAGTLKVSDNGPGISMRDREAVFEHGFSRKPGGRGLGLKISKDVLQRSGWSLRVDPTGGLPWPPSGLHDAVGPGGGRGAEFLIIPPGDEED
>NZ_CP025394|884712:1006869|986199_987261_-|WP_104814815.1|DBSCAN-SWA
MEQVQGEPDPQVVPAPPSRAAVFLVLAVEPGGHRAVREWLAGLGGLVRSLGLRAPEARLSCVAGVGAAVWDELYGGPRPAGLHPFRELRGPRHLAPSTPGDVVLHVRATRMDLCFELATRCTRGLAGAARVVDETHGFAYFDQRDLLGFVDGTENPVGAKAARAVYVGAEDPQYAGGSYLVVQKYLHDLGSWDALTVEQQERVIGRTKLADVELADQAADSHVALNQVEGPDGEEQQILRANMAFGSVGRGEYGTYFAGYCRTPEVTEEMLRRMFLGTAEAAHDRILDFSIAVTGSLFFVPDADFLADPPDPAGASLEAATGDGSLGIGGLKHLLHPAPTETPTEAPIETKAF
>NZ_CP025394|884712:1006869|900159_901689_-|WP_104814766.1|DBSCAN-SWA
MNTRGKSTEGGAAAAPEPIPPRAGPIELPGFGWRPVAGVAAGVVVLLLALAGRYGYHRDELYFLLAGRHLAWGYVDQPPLTPWLARLSELALGDSPLALRVLPALLAGVDVVLVALLAREFGGERRGQLLAAWATAGSAFVLATGHLLLTSSADLPASLGVLLLGLRLLRTGDGRWWLPLGAATGLALLNKDLVLLIGLALLAAVLVSGPRRALLSRWLPAGLALAVLVALPNLLWEAAHGWPQLTVANGITDKDGEQNRWLLLPLQLVLLSPAVVPLVLRGARRLRREPELSWARAYPLAYPLLLWLLSRFGGKAYYAVPLLLVLMAAGCAKPRGTGRVVTAGLLVGALVNVVITLPVLPPKALVAVGWIYPEAAEQVGWPQLASAAARGWAQIPPEQRDTAVLFAANYGEAGALARYGPGLGLPGPYSGHMSLADWGPPADRQAGPVLLVHPAGFGAVERQFTDCRPVGEVDTGQGVANQEQHAAVVLCAGPSRPWSQLWPQLRHYY
>NZ_CP025394|884712:1006869|968866_969511_+|WP_104814807.1|DBSCAN-SWA
MIVMQPVLEIYAPDDFALWPIAAWKQFEYLTLNGGLDPAEVGIAIMRIAECNDLDPDPENGDDRPPRPADPTESFLHGLLTFDSLHVTGGLRVTDTSTGITFVPGCCGGLEDWRDWSSVTDGTGAAMFGHDPVALAERDGDTVRLTVDREQSDSPVIELPVTDLRHLLAGAERDLTDFHQLAANWIAQHLPDQAIRVTAAVADALDLLQPNAAP
>NZ_CP025394|884712:1006869|1000497_1001022_-|WP_104814830.1|DBSCAN-SWA
MELTQYVENLRRELTVAAGVGGEDARALADRLLLPLDAAMRLTLLEALSAAAEEISAELAPGAVDVRLRGGEAAFVVTPPPGVGEPAGPAPAEVRVPVVEGEDAAMVRINLRLPAGLKGQIEDAAAAGGLSTNAWIVRAAAAGLAQEGRRSAPAPTRTAEQSGRVGQNWTGWAR
>NZ_CP025394|884712:1006869|966132_967659_-|WP_104820645.1|DBSCAN-SWA
MTDHALWLLRQDRRLAELAAFPFDFDLDRAAHGHVEEVRLASGGSLETVAGDDTGGTYFVCADGSVLYADSEGAAGIIGSSVDEALELVIGLPGWRGYTRLSPDDGEEKILACVAETEDEIREYYGIDEERAELRAALGFPKRSPVELVGRLRAALLRTEPEFVLLNADEGCAYDRIGPAGPPLWEPVLAAGRADLARLREGDRTAWREVAEDPVRRRITLRAAQFDRAEGDLELLRHLLRHETRSSMTDELRLAAVLVGLRGDTADLPLLLEVRETDFDTACGLGGIPEPGASADDLKQWARALDESMFGTDPMGEPVSTWTDLARDQGMTDLARVALIRELDDIFLDQSRLRRPEAPRTLTTAPLSGLARDFEELGDLPQALRAQHLYAALQETAWDQASARRTLARLEREAGRLSQAADSLAAVRDALAAPGDGSLRCWQQVNLGRFIAEEHYRLTLALAAAGRPEEARVLLTAADAILGELSENAANGIRELAERTAARVREVN
>NZ_CP025394|884712:1006869|888363_892227_-|WP_104814760.1|DBSCAN-SWA
MGAMTAEPNLPQRALFPGRPAAVPRTLVDLLEATVRDHPGEPALDDGRSVLTYRALAAEVEQLRRRLAAAGIGAGDRVGVRVPSGTNDLYVSILAVLAAGAAYVPVDAEDPEERAQLVFGEAEVAAVLGAERSLEVTAQRPAAEARRPGVADDAWIIFTSGSTGKPKGVAVTHGNAAAFVDAEAALFLQEEPIGPGDRVMAGLSVAFDASCEEMWLAWRHGACLVPVPRSQVRSGADLGPWLAEQEITVVSTVPTLAALWPAEALNEVRLLIFGGEACPPELVQRLVTEGREVWNTYGPTEATVVACAALLTGDGPVRIGLPLDGWDLAVVDEAGEPVALGEAGQLVIGGVGLARYLDPEKDAEKYAPLDSLGWRRAYRSGDLVQADPAGLLFLGRTDEQIKLGGRRIELGEVDAALQALPGVAGAAAAVRTARGGNQLLVGYLVIQDGFDREQAVERLRAELPAALVPLLAPVETLPTRTSGKVDRGALPWPLPELETAGPSEQLYGTEAWLAEQWAEILGVQVSGPREDFFAIGGGSLAAARLTTLLRTRYPNVAVLDIYQQPTLRKLARHLEGSGAESGEARTVALVPAKAKLLQLLLLIPLFTVVGLRWTVALLAAGNLLTHLGDFPWAPTASWWAVGAGALALYSPPGRLALAAGGARLLLRGLRPGSYPRGGSVHLRLWTAERLAEVTGATALSGSWLVRYARALGAKVAPEVDLHSLPPVTGMLKLGRGCAVEAEVDLSGYWLDGDRLEVGPLKVGSGATVGTRSALQPGAKVGKNAQVVAGSSVTGQVPTGQRWGGAPAVKLGRAERFWPKARAPRRAGWAALYGAGGALLSLLPVLPGLAALAVLALVVPQGAPLGEALGGALLGLLPATLAFGAVYAAQLVALVRVLSLGLVTGVHPVHGRVGWQAWTVTQLMDQAREVLFPLYAGLVTPYWLRALGMKVGRGAEVSTVLALPSLTTVGDGAFLADDTLMAPYELGGGWVRLGEAKVGERAFLGNSGMTAPGRSVPKRGLVGVLSATPEKAKKGSSYLGMPPMKLPRAADRADQSLTYEPPARLLWARGLVEVGRLLPVLASGALGLVTAAVLARVCAAWSPLVAALVSGLVLLAAGTVACLVAVVAKWVLVGRFRAVEHPLWSGFVWRNELADTFVEVLAVPWLVGAVPGTPVLNLWLRALGARVGRGVWCESYWLPEADLVTLGDGVSINRGCVVQTHLFHDRIMRMDTVVLREGATLGPGGIVLPGSTVGERSTLGPASLVMGAESVPADTRWLGNPIEAWQTT
>NZ_CP025394|884712:1006869|951471_951801_-|WP_158702019.1|DBSCAN-SWA
MDDVFDLSGAPPHGWMHAVFGGGPYGDDVGRCVPGPPAPASITVPLEGGGEHVYRLWAVGSWSAPDDPVAVYNNVGPTPDPPLSELEMSWLNRRNTSSSAAPRKFVEGC
>NZ_CP025394|884712:1006869|964932_965262_-|WP_104814805.1|DBSCAN-SWA
MGCRASLCPSALVPPPAYPLGDPRRHPRSLPRPGTLTVTPDGVRGPAPATAAVTIAPATGADIREVFCNRVNFYATTQLAEAAAEQATDLAACTVDEAWDIGKRLADLF
>NZ_CP025394|884712:1006869|955752_957249_-|WP_158702020.1|DBSCAN-SWA
MDRYGLYERLSRATEASTSIERRDEAARAEVKRRGGRVVGAFVDEGVSGALPPMDRPAMKELLQQLSGMDAVMVWKIDRIARSFLGFAEIVKELDKHGVALVSATEPIDMTGPTGRAMAQMIAVFAELEREMIKARVADSMRKAKEENRFHGGRIPYGLTVADHPSGKGRVLVRDTHAVGVLREVLLWVLEGATMAECARRLNDRKEPTSRQRGAVLKGLAKAEAAQWRGVSLKRILASPTMLGCRLLPGGKVQTNGDGLPVLVWDPVFSRDEWDALQTCLAELEQGPRKAPAASHWLSGCLKCSVCGGNLKQWVSGTGLRAFTCRGRETAAHSPSVYVPADLVADWVREQFPVVYGILPEVERRWVPGSDTSRELSEVRAAIRRLRDDRDIGLFDDDEDDYRERMARLVERRKVLQTVPQVEPHWEEHRTGRSLAEVWSGLSDERRGALMIEYGLALWVDPAPTKAKNTPINSRAQFGPSAPAEDALAAIAYAEGVC
>NZ_CP025394|884712:1006869|895866_897699_-|WP_104814763.1|DBSCAN-SWA
MCGIVGLVSFTTDLAQRPELGAAMRGALALRGPDAVGEWSSPRARFVPRRLAVVDLEGGHQPAVATDAEGRETVVLGYTGEVFNFVELREELRRRGHEFRDRSDTEVVLRAYQEWGAGCAERLRGMFAFAVWDVRREELLLVRDRFGIYPLYYAETPDGLAFGSEPKALFTTGLIAPVVDGAGLLEALSFTPTPGAAVFRGMREVVPGELVRYGRGGLHRARYWQFTPARHTDDLPTTERRVRALLEDIVDRQVAADVPISSMLSGGLDSSAVCALARQVVGGPLRTFSMEFAYHLDHFRPDEVHDSADAPYVARMAAHLGSEHRELLVDQAQLTDPEAQAEVVRAMDRPAAGLDMYVSLYRLSQEVRRHSTVTLTGDGSDELFGGYVWFHDPFYVRAETFPWLGASHRMEFLSGLLDRRLYAALDFPGHERARYREALAEVPLTGEEGPAERRMRELTYLNMTRYLRVVLDRKDRLGMAASVEGRVPFCDHELAEYVYNVPWAMKVADGREKSLLRAAVRDLLPTAVLERKKSPYPTVQDPAYRVALREQLRAIRAEKDAPVNELLDAGRVEAALEDPTFGLRAGVTRMSVEAAIQLHHWLSSGVTVAL
>NZ_CP025394|884712:1006869|911602_912436_+|WP_104814775.1|DBSCAN-SWA
MITRTDDPRLVLARRSVGPVTIIAEPGLPDRVLHLADSRGTRYFAKQHHQPARFTQEVNAYAGWARHLAARTPDLVAQHHADLVLLITAVPGRRANTLPPGSDAEQLAHRAAGAALRALHTATAITDPDLCSKISSRLRTWIAKAHQAELLSAREHQTLSEAADQLTHQRMEAAVCHLDYQPRNWCVGKTLAVVDFEHSRPDARIRDLARLAFRHWPRSPHLRQAFLSGYGCLTSVEENLLHLFAAYEAVTALVRGHENADRDLSAHGRATLARLLP
>NZ_CP025394|884712:1006869|982434_982860_-|WP_104814812.1|DBSCAN-SWA
MSEDGFQVVPEQYQAEVSPLLAASEQIRSVYTSLSAFLPALEAQNPWGNDESGKQFAEGDKGYLKYSKDTLDVLKGLPDALKGISDGLKAMAEGYQGADQDVVAELDGIDTGAAPLPAPPSMPDAPVHVPMTPRITQSGRH
>NZ_CP025394|884712:1006869|936673_937639_-|WP_158702016.1|transposase|DBSCAN-SWA
MPQMEVLRQVWVQQYWYDEEGRLGWRGPKQTRDRLSRRHSPRRSMAAEASDGRPDPASARVPWSSVEIVSPHDPQARFSHKPGKAEWVGYKDHQAETCDTGLPNVIVHVATTPAPEQDIDTLEQIHSDLAARDLAPAEHLVDGGYTSPATIHRARTEYGIDLVGPVRLPPRTRALPGFNKEDFLPNWEERTLTCPNGATSPPWKATLADGQPRLSVLFPRAVCRACDDRPRCTGNVDGKGRHLLLLPQPLQEIQNRVRKEQGTRDAGRLRSHRLRDRPRQRPAQLPLPRRREDPRPACPHRGRDQHHPPQKVLGKRVTTRS
>NZ_CP025394|884712:1006869|884712_885846_+|WP_104814759.1|transposase|DBSCAN-SWA
MAERVQVREIDDDEGRRLLRIVRRGTGSVVTWRRAQMVLLSAQRMPVAKIAEVTFTSADRVRDVIHNFNADGFDSLYPKYRGGRPRTFTLPERREIKKTAKSKPAEHGLPFSTWSLAKLADFLVAEGVVDDISHEGLRVLLREEGVSFQRVKTWKTSRDPDYAAKKARVEHLYAIADGEVVPEDGEPEVVFCLDEFGPLNLQPHPGKQWAERGGRHKDPDREPRPRRRATYTRPHGVRHLFAAYDLAKDQLYGHVKKTKNRSRFLEFCRYLRSLHPADVRIAIVCDNYSPHLTTKRCQRVGTWAAANNVEIAYTPTNSSWLNRIEAQFTALRYFALDGTDHPSHKAQGSMIRRYIIWRNKHAQDERLRKVVTRANVA
>NZ_CP025394|884712:1006869|904561_904900_-|WP_158702011.1|DBSCAN-SWA
MSADDPGVDGVVAEHFSDAGWWRLKGQLLQSRGSAVESGDARDGELPSEARRVHQLPGSAVGREAGLDLWAAAELGAVHISLIQGAKVVSALEIAPEERSSAWEILVGFLSC
>NZ_CP025394|884712:1006869|996169_997657_+|WP_104814826.1|DBSCAN-SWA
MALELPAELEPVLGLLGVEWPQVNEDELNRFADELRKFASAIDSTQMAADKAVSALGQVYHGASADQLAQAWSAISKFSELVVQGCGLVANAVSAAAIVVEMCKGGAIAQLAVTSGGLATAAATAPWTTPAVLATGKQIVSQILESAVTELGHALAQPVADLVDTAVKAVTGGASAGAGGSAGQGFGVDLAKLASTALQLRGHADDVNSSGSAFLQIFDSMDLGQPGEIIGKVVTEAAEQIATTVGTEVLKRLLSSFTGTADNMDQIGKNLSQNEDEHSRLMSNLLSAPTPVAALTPGRLAGTSTLSTDSAAGPSASHTGIDSLRPRLGTTNAGGYDGTDGGTDGGDGTVNAGQPGTQPSVVLQQSESPTSHSLPTAPVQSGTTNPGSTGTRSSADAPGEEHPTATTAGSPAAGAANNTYGRTGKSNGRSTNTGTTGTGTGTGSRPIQDLGVQGRAKRAKAEEDEERARAEHRPAELPDGLPAELPTEEAVEAGR
>NZ_CP025394|884712:1006869|930882_933441_-|WP_104814783.1|DBSCAN-SWA
MTDEFDEMYDTFKALLDSFPPSEAVKRLERLGISPDIVERIRERHEQQTVRIRELEEPHAVILGNRDTWYTGPQPKDKCWPAITDLLRKDDWPPEPAIRSLDDSSTRVVSLLNHPKQKAFSTRGLVVGYVQSGKTTNFTSVVAKAADRGYKLFIVLAGIHNGLRRQTQARLVQQLVEPNPSLWSQLTGLDKDFTPGENPASYFGRNNRTHVLCVVKKNATVLRKLAAWLEKASDYLEDCPALIIDDEADQATVATKSINPLILGIMSSLPRSAYVGYTASPFANLLIDPSAADLYPKDFVVNLPKPEGHFGTEVLFGRYALDGEDPEQVDDGYDMIRSVPDDDVAAVRPETRADVEGFEPFITDTLRRAVEYFWLVTAARRVRGTGDPHNTMLIHTSVNTAVHNSFKRPLEHLRDRFERSLSAGDADFLARLSDLWESETERVPAEDFGETKVPFERLLPELSGVLESCRVIMDNSSSEDRLDYENGPVVAIAVGGNTLSRGLTLYGLSVSYFVRSVSAYDTLLQMGRWFGFRKGYADLPRIWMTDELAEWFRHLATVETEMRRDIDIYMTEDETPLTFAVRLRTHPALRVTAAAKMRDAVTAASSYGGKRVQTHYFHTNAGWLGRNADAARALIKASVANAVRAEERPAEGRYVFRDVPHDLVIDFLSTYRFHEKSPENDADLIIDYIRKRVSKAGSLGRWNVAIVGNPKGEDFAFAPGVSVGRNNRARLDLPNPVPDFADIKTLMSRRDAAVDLAGDTGKLTEKGIMEERRRQLPDTGLLVLYPIDKVSEPLPAKRLRVPLNAEDHVIGVGLVFPEPRHGDSTVESYVSANLSNVRIEDEDYSVLDDEDA
>NZ_CP025394|884712:1006869|894298_895804_-|WP_174805622.1|DBSCAN-SWA
MRPAWSLVDVLVATCAAHPARVAVVEGEAAYSYWQLDRLSGEIAAGLAARGVRPGQAVGLLAPRGWWRCAAVLGIWRAGAAVNSLDPAQPAARAARVVELSGTALVLRGPGVAPGGYGVPEVEIGEVLLRGAQLTEEGPLGYVVTTSGSTGDPKCVAVPTVVLADLAEWHCAGWRSAELPRTSHAASVGFDVGYQELVATWVAGAALVVADEEQRRDPFLLAELLHRHGVVRSFLPVTGLHALAVACAATGRRLPALREVVVAGERLVVNAEVRALFATLDAELVNHYGPSETHLVTEHRLSGDPAGWPAHPALGGPAVGAELLREDGGLVRPFAEGEEAELLVAGRCLALGYLGDERLTAERFREVAGWDGVVRRVYATGDRVRLADGLLHFLGRGDDQLKVRGYRVEPGEVEAVLSRLPGVRRAAVVGRSRAGSTTLHGYLVLDPAAAGPDAAALRAACAAELPEYMIPARFLRVAELPLLASGKVARRELDGTGTPIR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_104814759.1|884712_885846_+|transposase	IS630 family transposase	NA	NA	NA	NA
WP_104820640.1|887002_888325_-	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	1.9e-12	23.4
WP_104814760.1|888363_892227_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.8e-34	25.6
WP_158702009.1|892446_894276_-	hypothetical protein	NA	NA	NA	NA
WP_174805622.1|894298_895804_-	AMP-binding protein	NA	NA	NA	NA
WP_104814763.1|895866_897699_-	asparagine synthase (glutamine-hydrolyzing)	F2Y1H0	Organic_Lake_phycodnavirus	3.3e-23	27.7
WP_104814764.1|897817_899053_-	MFS transporter	NA	NA	NA	NA
WP_158702010.1|899024_899996_-	RimK family alpha-L-glutamate ligase	A0A1D7S9D1	Synechococcus_phage	6.4e-26	34.0
WP_104814766.1|900159_901689_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_104814767.1|901809_902481_+	hypothetical protein	NA	NA	NA	NA
WP_104814768.1|902555_904022_-	GuaB1 family IMP dehydrogenase-related protein	A0A1V0SHK8	Klosneuvirus	3.1e-48	29.7
WP_158702011.1|904561_904900_-	hypothetical protein	NA	NA	NA	NA
WP_104814769.1|905513_905957_-	hypothetical protein	NA	NA	NA	NA
WP_104814770.1|905953_907204_-|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	6.3e-151	65.0
WP_158702012.1|907340_907865_+	hypothetical protein	NA	NA	NA	NA
WP_104814772.1|907958_908465_+	topology modulation protein	NA	NA	NA	NA
WP_104814471.1|908776_909322_+	hypothetical protein	NA	NA	NA	NA
WP_104820582.1|909278_910070_-|transposase	IS5 family transposase	NA	NA	NA	NA
WP_158702013.1|910401_910959_+	phosphotransferase	NA	NA	NA	NA
WP_104814774.1|910955_911606_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_104814775.1|911602_912436_+	aminoglycoside phosphotransferase	NA	NA	NA	NA
WP_104814776.1|913513_914278_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_174805623.1|914545_915664_+|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.1e-37	34.3
WP_158702014.1|916463_919727_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_158702015.1|919651_920827_+	hypothetical protein	NA	NA	NA	NA
WP_104820641.1|921137_922022_-|transposase	IS5 family transposase	NA	NA	NA	NA
WP_104814780.1|922428_923580_-	restriction endonuclease	NA	NA	NA	NA
WP_104820642.1|923884_924949_-	DNA cytosine methyltransferase	A0A0U4IHB6	Streptomyces_phage	7.3e-76	51.7
WP_104820643.1|925060_926104_-	DNA cytosine methyltransferase	G9BWB3	Planktothrix_phage	7.3e-12	24.1
WP_104820644.1|926982_927399_-	hypothetical protein	NA	NA	NA	NA
WP_104814781.1|927872_929864_-	hypothetical protein	NA	NA	NA	NA
WP_104814782.1|929860_930886_-	PD-(D/E)XK motif protein	NA	NA	NA	NA
WP_104814783.1|930882_933441_-	endonuclease	NA	NA	NA	NA
WP_104814784.1|933734_934466_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_104814785.1|934566_935241_+	very short patch repair endonuclease	E5E3X5	Burkholderia_phage	1.1e-16	42.5
WP_104820641.1|935802_936687_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_158702016.1|936673_937639_-|transposase	transposase	NA	NA	NA	NA
WP_104814788.1|937967_938807_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.5e-10	30.1
WP_104814788.1|939070_939910_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.5e-10	30.1
WP_104814789.1|941639_944663_+	ATP-binding protein	A0A1B5FPD5	Escherichia_phage	1.1e-39	25.7
WP_158702017.1|944689_946384_+	hypothetical protein	NA	NA	NA	NA
WP_104814791.1|947358_948177_-	hypothetical protein	NA	NA	NA	NA
WP_104814792.1|949206_949977_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	6.1e-56	45.0
WP_158702018.1|950014_951094_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_104814794.1|951141_951471_+	hypothetical protein	NA	NA	NA	NA
WP_158702019.1|951471_951801_-	hypothetical protein	NA	NA	NA	NA
WP_104814796.1|953602_954364_-	hypothetical protein	NA	NA	NA	NA
WP_104814797.1|954451_955300_-	hypothetical protein	NA	NA	NA	NA
WP_158702020.1|955752_957249_-	recombinase family protein	H7BV64	unidentified_phage	8.3e-17	29.5
WP_158702021.1|957634_961057_+	CHAT domain-containing protein	NA	NA	NA	NA
WP_104814800.1|961031_961511_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_104814801.1|961617_962679_+	DUF2332 domain-containing protein	NA	NA	NA	NA
WP_104814802.1|962737_963514_+	arylamine N-acetyltransferase	NA	NA	NA	NA
WP_104814803.1|963526_964225_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_104814804.1|964415_964859_+	nitroreductase family deazaflavin-dependent oxidoreductase	NA	NA	NA	NA
WP_104814805.1|964932_965262_-	hypothetical protein	NA	NA	NA	NA
WP_104820645.1|966132_967659_-	hypothetical protein	NA	NA	NA	NA
WP_158702022.1|968502_968907_+	hypothetical protein	NA	NA	NA	NA
WP_104814807.1|968866_969511_+	hypothetical protein	NA	NA	NA	NA
WP_104814808.1|970333_970678_+	SHOCT domain-containing protein	NA	NA	NA	NA
WP_104814809.1|970796_972278_+	SDR family oxidoreductase	A0A1V0SKJ3	Klosneuvirus	1.1e-32	28.8
WP_104814810.1|972328_972781_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_104814811.1|972869_982430_-	hypothetical protein	NA	NA	NA	NA
WP_104814812.1|982434_982860_-	hypothetical protein	NA	NA	NA	NA
WP_104814813.1|983056_985276_-	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_104814814.1|985401_986196_-|bacteriocin	bacteriocin family protein	NA	NA	NA	NA
WP_104814815.1|986199_987261_-	Dyp-type peroxidase	NA	NA	NA	NA
WP_104814816.1|987420_987861_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_104814817.1|987952_988372_+	VOC family protein	NA	NA	NA	NA
WP_104814818.1|988457_989003_+	hypothetical protein	NA	NA	NA	NA
WP_158702023.1|989025_989751_-	hypothetical protein	NA	NA	NA	NA
WP_104814820.1|989747_990452_-	hypothetical protein	NA	NA	NA	NA
WP_104814821.1|990525_991215_-	NADPH-dependent F420 reductase	NA	NA	NA	NA
WP_104814822.1|991308_992130_-	ABC transporter permease	NA	NA	NA	NA
WP_104814823.1|992126_993107_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.6e-21	31.2
WP_104814824.1|993220_993655_-	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_104820646.1|993943_994726_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_158702024.1|994776_995262_+	hypothetical protein	NA	NA	NA	NA
WP_158702025.1|995350_995986_+	hypothetical protein	NA	NA	NA	NA
WP_104814826.1|996169_997657_+	hypothetical protein	NA	NA	NA	NA
WP_104814827.1|997747_998575_-	ABC transporter permease	NA	NA	NA	NA
WP_104814828.1|998608_999550_-	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	1.2e-18	29.4
WP_104814829.1|999546_1000437_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_104814830.1|1000497_1001022_-	hypothetical protein	NA	NA	NA	NA
WP_104814831.1|1001188_1001758_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_104814832.1|1001805_1002723_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_104820647.1|1002741_1003683_-	hypothetical protein	NA	NA	NA	NA
WP_104814833.1|1003903_1004302_+	hypothetical protein	NA	NA	NA	NA
WP_104814834.1|1004382_1006869_+|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.6e-134	40.9

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP025394|1353930:1416764|DBSCAN-SWA
GTTACGCGCCGCGCAGCACCGCGCCCGTGCGGGCGTTCGCCTCGGCGACGGCGGCGGCGCGGGCGGCCGACGCCTCCTCGGCGGTCAGGGTGCGGTCGGTGGCGCGGAAGCGCAGGGAGTAGGCCAGCGACTTCTTGCCCTCGCCCGCCTGCTCGCCGGTGAAGACGTCGAACAGGCGGATGGCCTCCAGGAGTTCGCCCGCGCCCGAGCGCAGGGCGGTCTCCACCTCGGCGGCCGGCACAGCGGAGTCGACGATCAGCGCGACGTCCTGGGTGGCCACCGGGTAGCCGGAGACCGTCGGGCCGCTGACCCGCTGCTCGCCGCCGGCGAAGAGCAGGTCGAGGTCGATCTCCATCGCGCTGGTGCGCTCCGGCAGGTTGAGCGCCTTGATCACCCGCGGGTGCAGCTCACCGGCGTGGCCGACCACGGTCTCGCCGACCAGCAGCTCGGCGCAGCGGCCCGGGTGCCACGGGGCGGTGCGGCCCTGGCGGACCGTCAGCTCGACCCCGGCGGCCGAGGCGACGGTACGGGCCGCCTCGATCGCGTCGGCCCAGCCGGCCGGAGCGCCCTTGCCCCACCAGCCGGACGGCAGCCGCTCGCCCGCGAGGGCCACGGCCACCCGGCGCGGCTGGTGCGGCAGCGCCGCGTTGAGCGTGGCCAGCTCCTCCTCGGTCGGACGGCGGTCCACCGGCAGGCGGGGAGCCACGCGCAGCTCCGCCTTGGGGAGGAAGACGGTGCCGGCCTCGAAGATCGCCAGGTCGGTGTTGCCCCGGCCGATGTTGCGCCGCAGCGCACCGAGCAGGCCCGGCAGCAGCGTGGTGCGCAGCGCCGGCTCCTCGTCGTTCAGCGGGTTGACCAGCTTCACCGTGCGGCGGCGCTCGTCGTCCTTCTCCAGGCCGAGCGCGTCGAACGCGGCCTCACCCAGGAAGGGGTAGTTGTTGACCTCGACGTAGCCCGCGCCCGCGAGCGCCACGCCGGTGCGGCGGTGGAAGCGCTGCGCCTCGGTCAGGCCGCGGCCCGGCGGCACGGTGGGCATCCGGGCGGGCACGTTGTCGTAGCCCTCCAGGCGGATGACCTCCTCCGCGAGGTCGTACGGGTCGGTCAGGTCGGGGCGCCAGCTCGGCGGGGTGACCTCGAGGATGTCGGCGCCCGCGACGGTGCAGCCGATCTCCTGCAGGCGCCGGGTGACGGTCTCGCGGCCGTACTCGGTGCCCGCCACGCGATCCGGCAGGTCGGCGTCGATCGCGATGGTCCGCAGCGGGTGCGGGGCCGCGATGTCGGTGACCCCGGCCTCGGCGGTGCCGCCGGCGATCAGGACCAGCAGGTCCACGGCGCGCTGCGCGGCGGCCCGGGCGGCCTCCGGGTCGACCCCGCGCTCGAAGCGCTTGGAGGCCTCGGAGGGCAGCTTGTGCCGCTTGGCGGCGCGCGCGATGGTGACCGGCTCGAAGTGCGCGGCCTCGATGATGATCTCGGTCGAGCCGGTGACCTCGCCGGTCTCCGGGTCGGTGACCGGGTCGAGGATCTCGGTCGAGGCGCCGCCCATGACACCCGCCAGGCCGATCGGCCCGGAGTTGTCGCAGATCAGCAGGTCCTCGGCGGAGAGCTTGCGCTTGGTGCCGTCCAGCGTGGTCAGCACCTCGCCCTCGACGGCGCGGCGGACCTGGATCGGGCCGTCCACCCGCTCGCGGTCGTAGGCGTGCAGCGGCTGGCCGACCTCGAGCATCACGTAGTTGGTGATGTCCACGGTCAGCGAGATCGGGCGGATGCCCGACTTCTGCAGCCGGCGCTGGAGCCAGATCGGCGACTTCGCGGCCGGGTCGACCCCGGTGACGGTGCGCGCCACGAAGCGGTCGCAGCCGGTCGGGTCGGCGACCTTGACCATGTACCCGTAGGAGTTGGCCGGCGGCACGTCCAGCAGCGCCGGGTCGGCCAGCGGCAGCCCGTAGGCGGCGGCGGCCTCGCGGGCCACGCCGCGCATGGAGAGGCAGTAGCCGCGGTCCGGGGTGACGGCGATGTCCAGCACCTCGTCGACCAGCTGGAGCAGCTCGATCGCGTCGGTGCCCACCTCGTACTCCGGCGGGAGCACGATGATGCCGTCGTGGTCGTCGCCCATGCCGAGCTCGCGGGCGGAGCAGATCATGCCGGCCGAGGTCTGGCCGTAGGTCTGCCGCGCGGCGATCGGGAAGGGGCCGGGCAGCACGGCGCCCGGGAGCACCACGACGACCTTGTCGCCCACGGCGAAGTTCCGCGCGCCGCAGACGATCTCCTGCGGCTCGCCGGTGCCGTTGGCGTCGCCGACGTTGACGAAGCAGTGGCGGATCGGCTTCTTGAAGCCGGTCAGCTCCTCGATGGAGAGCACCTGGCCGACCACCAGCGGGCCCTTGAGGTCGGTGCCGATCTGCTCGACCGTCTCGACCTCCAGGCCGGCCCGGACGAGGCGGGCGGCGACGTCGCGGCCGGTCTCGCCCGCCGGCAGGTCGACGTACTCACGCAGCCAGGAAAGCGGGACGCGCATCAGATCTCCATCCCGAACGGGAGGGTGAAGCGGACGTCACCCTCGACCATGTCGCGCATGTCGGCGACGTTGTGTCGGTTCATCAGGATCCGCTCCAGGCCCAGGCCGAAGGCGAACCCGCTGTAGCGGTTGGGGTCCACGCCGCAGGCGACCAGCACCCGGGGGTTGACGACGCCGCAGCCACCGAGCTCGATCCAGCCCTCGGAGGAGCAGGTGCGGCAGGGCTTGTCCGGGTTGCCGATGCTCTCGCCCCGGCAGACGAAGCACTGCAGGTCGATCTCGGCGCTCGGCTCGGTGAACGGGAAGTACGAGGGCCGCCAGCGCAGCTCCAGGCCGTCGCCGATGAGCTTGGAGACCAGCAGCTCGATGGTGCCCTTGAGGTCGGCGAAGGTGATGCCCTCGTCCACCGCGAGGCCCTCGACCTGGCGGAAGACCGGGGTGTGGGTCGCGTCCAGCTCGTCGGTCCGGTAGACCCGGCCGGGGCAGACCACGTAGACCGGCGGCTCGCGGTCGAGCAGGGTGCGGGCCTGGACCGGGGAGGTCTGGGTGCGCAGCACCACACCGGAGTCGGCGGAGCCGTCCGGGGCCTGCACGAAGAAGGTGTCCTGCATCGAGCGGGCCGGGTGGTCCTCACCCAGGTTGAGCGCGTCGAAGTTCAGCCACTCGGCCTCGACCTCGGGGCCCTCGGCCACCTCGTAGCCCATGGCCACGAAGGTGTCCTCGATCCGCTCGGCCAGGGTGGTCAGCGGGTGCCGGGCGCCGCGCGGGGTGCGGTCGTACGGCAGCGTGACGTCCACCGCCTCCTCGACCAGCACTCGGGCGTCCCGCTCCGCCTCCAGCTCGACCTGGCGCTTGGCCAGCGCCTGGTTGACGGCGCCACGGGCCTGGCCGATCAGCTTGCCGGCCGCGGCCTTGGCCTGCGGCGGCAGCGCGCCGATCTCGCGGTTGGCCAGCGACAGCGCCGAGCGGTCGCCGGTGTGGGCGACCTTGGCCGCCTTCAGCTCCTCCAGCGTGGCGGCGGCGGCGAAGGCCGCGACGGCCTCGTCCCGGGCGCGCTCGACCTCTTCGGGCTTCAATGCCTCGACCTCTACCGGGTCGTAGGACTTGTTGGGTGCGGACATCTCTATCTTTCCCGTGCTCCTGCTCGTGTTGTGCCGAGGTATGGGCTCGCGCCTCCCGCGGCCACGCCGCGCCAGGGCGTCGCGCAACGCCAAAGGACGAGTGTAGTCGCAGCCCGCGTAACGCCCGTTCGCCCGATTACTCAGAGCATGCTCTCCGTGCTCGTCAGAGCATGAAGTCGGGGACGCCCGCGGGCAGGATAAATCGGAACTGGGCCCCCCGCCGGGCGCGCGGCTGATCCGGATGGTGCCGCAGTGCGCCTCGACGATGCCCTTCACGATGTAGAGGCCGAGGCCCGTGCCGCCGCGCTTGGAACCGCGCCAGAACCGGGTGAAGACGCGCGGCATCGACTCCTCGGGGATGCCGGTGCCTTCGTCGCTCACGGTGACCGACGTCCCTTCCATGACCTTGGGCGGAGTGCCGGGGCGCTCCCAGACGGCCGCCTCGACCACTTCCTTGGCGGGGGCCACCTCGATGGTGACAGTTCCCTCGCCGTGCCGCACCGCGTTTTCCAGCAGGTTGGCGAGCACCTGGTCGATCTTGTCCGGGTCGGCCCAGAGCTGGGTGAGCGGCTCGGTGATCCGGATGTCGAACCGCTCGGCCGGGCAGCCGGCGGCCACCTTGCCGTCCACGTGCCGGCGCACCGCCGCGGCCAGGTCGACCACCTGCTTGCGCAGCTCCAGCCGGCCGGCGTCGATCCGGGAGATGTCGAGCAGCTCGGCGATCAGCCGGGTCACCCGGTCGGCGTCGGCGTCCACGCTCTCCAGCATCCAGCGCTTCTGCTCGTCGGTGAACCGCTCCCACTTGGCCAGCAGGGTCTTGGTGAAGCCCTTGACGCTGGTGAGCGGCGAGCGCAGCTCGTGCGCGACGGTGGCGATCAGCTCGGCGTGTCCGCGCTCGGTGCGGCGGCGGGCCTCGGTGCCGCGCAGCGCCACCACCACCCGCTCCACCGGCCCCTGCGCCCGCTCCCGGACGTACCGGGCGGAGACCAGCACCTCGCGCCCGCCGGGCAGCAGCAGGTTGCGCTCTGGCTGCCCGGTGCGCACGGCCAGGCCGCCGTACGGGTCGGTCAGGGGCCACCAGCGCCGACCGTCCAGGTCCTCCAGCGGCAGCGCCTGCTCCAGCGGGGTGCCCAGCGCGGTGGCCGCGCGGATGCCGGTGAGCCGGGCGGCGGCGGCGTTGAAGCAGACCACGGTGCCGGTGCGGTCGGCGATCACCAGACCGTCCGGCAGGTCGTCCGGGTGCCACTCGGACCCGCTGCCGACCATGGGCGCCCTCCCCAGTAACCCACTACCCACTGTGTGCGTCCCCCCACTGTCCGAACCCTAGCGCCCCGATCACGTCCAGGCGAGATCCAGCACGGTCACGTCCGGCAGCCGCCCGGGGAGCGCTGGGCGCGCGCCGAGGCGTAGAGGCAGACGGCGGCGGCGGTGGCCAGGTTGAGGCTCTCGGCGTGGCCGTGGATCGGCACCTTCACCACCTCGTCGGCCAGCGCCCTGGTCTCCTCCGGCAGGCCCCAGGCCTCGTTGCCGAAGACCCAGGCGCCGGGCGCGCCGAGGGTGCCCTCGTCCAGCTCCTGGTCCAGGTCGCGCTGCCCCGCACCGTCGGCGGCCAGCACCCGCACCCCGGCCGCGCGCAGCCGCCCGACCGCCTCCTCCACCGGCACCCCCACCGCGAACGGCAGGTGGAACAGGCTGCCCACCGAGGCCCGGACGGCCTTGGGGTTGTACGGGTCCACCGAGGCGTCGGTGAGGATCACGGCGTCGGCCCCGGCGGCGTCGGCGGTGCGCAGCACGGTGCCCGCGTTCCCGGGGTCGCGGACGTGGGCGAGGATCGCCACCAGCTTCGGGCGGGCCGCGAGGACGTCCTCGAACGGCGTGTCCAGGAAGCGGCAGAGCGCCACGATGCCCTGCGGGGTCACCGTGTCGCAGATCTCGGCGATCACCTCGTCGGTGGCGGTGAGCACCGGCAGCCCGGCCGTCAGCGCGGCCTCGACGATGTCGGCGTGCCGCTCGGCCGCCTCGGGGGTGAGGTAGACCTCGACCACCACGTGCTCGCTCGACCCGGCCGGCCGCCCGTACGCGACCGCCTCGCGGACGGCCTGCGGGCCCTCCGCCAGGAAGCGCCGCTCCTTGCTCCGCTGGTTGCGCCGGGCCAGCTTGCGGGCGGCGATGACGCGGGGCGAGCGCAGGGAGGTGAGCAGGGGGGTGTCGGTGCTCTGCATGCTCTCGATCTCTGTGGACGGGCCAGGCGATCTGGGTGGACGGGCCGGGCGGAAATGCACTCGGCCCCGCAGACGGAGCGCCTGCGGGGCCGAGGAAAGCTTGGTGCCTCAGCGGGCACCGAATCCGTGCCGTCCGCCCGTCACCGGGCGGTCAGGGGCGGATTCAGGCGGCGACGGCGGCCTTGGGGGCGTTGACGTCGGCCGGGAGCGCCTTCTGGGCGACCTCGACGAGCGAGGCGAAGGTGGCCGGGTCGTTCACGGCGAGGTCGGCCAGCATCTTGCGGTCGATCTCGACGTTCGCGATCTTCAGACCCTGCACGAAGCGGTTGTAGGTGATGCCGTTGGCACGGGCCGCAGCGTTGATGCGCTGGATCCAGAGCTGGCGGAAGTCACCCTTGCGCTTCTTGCGGTCGTTGTAGTTGTAAACGAGCGAGTGGGTGACCTGCTCCTTGGCCTTGCGGTACAGGCGCGAGCGCTGGCCACGGTAACCGCTGGCGCGCTCGAGGATGACCCGGCGCTTCTTGTGGGCGTTGACTGCCCGCTTGACGCGTGCCACTTCATTACTCCTTGGGTTGGACCACGGACTACTTCACGTGGTCCGTCAATCGAATGGGTCGGGAAGGATCAGCTGCCCCGCGAGCACCTTGCGGGCCGCGGGAGGGCGATCACAGCCCGAGAAGCTTCTTGATCTTCTTGGCGTCGCCGGGGGCCATCTCGGCGTTGCCGGCCAGCTTGCGGGTCAGCGTGGAGGGCTTGTGCTCAAGGTAGTGGCGACGGCCGGCGCGCTCACGCAGCACCTTGCCCGAGCCCGTGATCTTGAAGCGCTTGCTCGAGCCGCTGTGGGTCTTCTGCTTCGGCATATCGCCGTTTCTCCTCGTCGGTCCGTCCCCGCCCCTGCATCGCTGCGGGGGCGGGAACTGGATGGATCCTCGGTGCCCGGGCGGGACGCCCCGGTACCGTCGTGGCCGATCCACCCGGACTGCGCGGAACCCCGGAGGGCTCAGGCGTCCTGAGTGGCCTCGGCCGGCTTCTCGACCTCGGCGGCGTCCTCGGCAGCCTCGGTGACCTCGGCGGTCTCCTCGGCGTCCTCGACGTCGTCGATCTCGTCGGCCTCCGCCTCGGCGGCGGCGTTCTCGGCCTCGAGCGCCGCGTCGTCAGCCGCAGCCTGGTCGTCGGCGCCGCTGTTGCGGCCCTGACGCTCGGCCTTGCGGGCGTCCGCGATCGCACGGGCCTCGGCCATCGCCTCGGTCTTCTTCTTGTGCGGGCCAAGCACCATGATCATGTTACGGCCGTCCTGCTTGGCCGAGGACTCCACGAAGCCCAGGTCCTGGACGTCGTTGGCGAGCCGCTGGAGCAGTCGGAAGCCCAGCTCGGGGCGGGACTGCTCACGACCACGGAACATGATCGTGATCTTGACCTTGTCACCCTGCTTGAGGAACCGGACGACGTGACCCTTCTTGGTGTCATAGTCGTGCGGGTCGATCTTCGGCCGGAGCTTCATCTCCTTGATGACCGTGTGCGCCTGGTTCTTGCGCGCCTCACGGGCCTTCATGGCCGACTCGTACTTGAACTTGCCGTAGTCCATGAGCTTGCACACCGGCGGCCGGGCGGTCGCCGCGACCTCGACCAGGTCGAGGTCGTACTCCTGCGCGAGCTCCAGCGCCTTGGCAAGCGGCACGATGCCGACCTGCTCGCCGCTGGGACCGACGAGTCGCACCTCGGGGACGCGAATCCGGTCGTTGATGCGGGGCTCGGTGCTGATGGGGCCTCCTTGGTTGCACCTTCTGCGCCGCGGCCGTCCGACGGCCGCGGGTAGTGGACTCGACCACTGGGCGGGGCTTCATTCGTGCTGCGCTGCCTTGCGGCTGCATGCACCGCGACACGAAAAAAGCCCCGCTCGGTACAGGCGGGGCTCCACACAACCGGAGGCTGCGCCCCTTGTCTCTGGGACGCTGCTGGCGACTCCCTGCGCCCTTGCGGGCCGGTGTCGCGGACCGGAGACCCGTCGACCGCGAGGTCGATCAGGTGGGAGACTTTCGTGGTTGCCCTCTCGGGCCTCCTGAGTGGAGCCTCCACTTGCTGGCCTGGTGCCCATGAGAGCTCCTGGCCGGTCAGTCTCGAAGCTTACGCTACTGATGCCGGTATTGAAAATGCGGGCTTGTACGCTGGGTGGCGTACTTCTGCCAGCCCCGACGGAGTGAGCCACCTTGAGCGCCCAGCCCACCGACCCGACCGACCTCGCCGAGGACCAGATCGGCTTCGACGACCTCACCCGTGACATCGCGGAGGTCCCGGCCGTCGAGGTGATCACCACCGTCGCGGTGCACCTGATGAGCGCGGCGGCCGTCAAGTGCGGCCTCGCCGAGGGCGGCGAGGCCGACAAGGACCTCGACGAGGCCCGCAAGCTGATCACCGCCCTGGCCGGGCTGGTCACCGCCGGCGCCCCTGAGATCAGCAACTTCCACGCCGCCCCGCTGCGGGACGGCCTGAAGTCCCTCCAGCTCGCCTTCCGCGAGGCTTCGCTGGTGCCGGACGCTCCGGGCGCCGGGCCCGGCGAGAAGTTCACGGGCCCCGTGTACAGCTAGTTGCACCATTCAGGGGCGCGGGGAACTGCGCGGATGCGGAAGGTGGCCGACCTGTTGCCTTCCGGATCCGCGCGGTTCCCCGCGCCCCTTTCTTTTGGCGCGCGCCCCAGTGAGGTTCACGCCCCCAGCAGGGCCAGGTCGAGGCCCCGCGTCAGGCGGACCCGCAGGATCGGGTCGGCGGCGAGGGCAGCGGCCAGGCGGCCGGCCAGGGCGCGGATCTCCTCCTCCGGGAGGTCCTCGGCCAGGGCCAGGGCCAGCACGGCGTCGGTCTCGGTGCCGGGGCGCAGCTCGGCGCGGCGGACGGCCGGCTCGACGGCCAGCACCGCGCGGACGGCGGCCTCCACCTCCGGGTCCTTCAGCGGCGGGAGGTAGGGGCGGTTCTCCGCCACGGCCCGCATCGGGGCGCCGGTCAGCTCGTAGGTGACCGGGCCGGCCGGGTCGATCAGGAGCGAGCCGGCCCGCTCGGAGTAGGCCGTCACGGCGGCCTGCGGGGCGGCCACCGGGGCCGGGCGGGCGTCGGCCCGCCAGCGGGCCAGGGTCTCCAGCGAGGTGAAGGCCGGCAGCGCGCGGCGCCCGTCCGGGGCCTCGATCACCGGTACGGCCATGTCGCTGGTCTTCTCGTGCTTGTGCCCGTTGGCGTCCACCTCGACCTCGCCGAGCAGGGCCACGATCGGGACCATCAGCCGGCTGGGCGTCAATGCGGTGAGCAGCGCCCGCTCGGTCTCGGCCGTACGGTCCGCCGCCCAGGCGGCGAGGGCGGCGGTGAGCCGGGGGTCGGCGGTGCCGTCGTCCTCGGCGAATCCGGGGTTCGGGATGTTCTTGCGGTCCACCCGGTGAGCCTATGCCACCTAGGCCTCTCATCCGGCGGTGCCCGTTCGTGCCGAGCCCTACCCATCAGTACGGGTGGTGTGACAGTCTGCGGGCCATGGCGATGCCGACTGCCTCCGACCGGGCCCGCTACGACCGGGCCACCGCGCACCTCGACGCCCCCCTGGCGATCGTCGACCTGGCGGCCTTCGACGCCAACGCCGCCGATCTGGTCCGCCGGGCGGCGGGCAAGCCCGTCCGGGTGGCCAGCAAGTCCGTCCGCTGCCGGGCCCTGCTGGAGCGGGTGCTGGCGATGGACGGCTTCGCCGGCGTCATGAGCTTCACCCTGGCCGAGTCGCTCTGGCTGGCCAGCGAGGGCTTCGAGGACGTGCTGCTCGCCTACCCCTCGGCGGACCGCACCGCCTTCGCCGAGCTGACGGCGGATCCGAAGCTGGCCGCCGCCGTCACCGTGCTGGTGGACGACCCCCGGCAGCTGGACCTGATCGACGCCGCGCGCGGCGGCAGTGAGGAGGTCCGGGTCTGCCTGGAGCTCGACACCGCGCTGCACCTGCTCGGCGGCCGGGTCCGGATCGGCGCGCGGCGCTCGCCGCTGCGCACCCCGGAGGACCTGGCCGACCTGGCCGAGCTCATCCAGCGCCGGCCGGGCTTCCGGGTGGTCGGGCTGATGGCGTACGAGGGCCATGTCGCCGGGGTCGGTGACCGGTTGGCCGGGCGGCCGGTGCGGTCGCGGATGATCCAGCTGATGCAGGCCAAGGCGCGGGCCGAGCTGGCCGACCGGCGCTCGGCGGTGGTCCGCCGCGTCCGGCAGGTGGCCGACCTGGAGTTCGTCAACGGCGGCGGCACCGGCAGCGTGGAGAGCACCGTCGCCGAGGCGGCCGTCACCGAGGTGGCGGCCGGCTCCGGCCTGTACGTGCCCCGGCTCTTCGACAACTACCGCTCGTTCCAGGGCCGCCCCGCCGCCCTCTTCGCTCAGCCGGTGGTCCGGCGCCCCGGCCTCGGCGTGGTCACCGTGCTCGGCGGCGGCTACCCCGCCTCCGGCGCGGCGGGCCCGGACCGCTCGCCAGTGCCGTACCTGCCCGAGGGCCTGCGGTACGACCCGCAGGAGGGCGCGGGCGAGGTGCAGACCCCGCTGCTCGGCTCCGCCGCCGACGACCTGCTGATCGGCGACCGGGTCTGGTTCCGCCACGCCAAGGCCGGCGAGCTCTGCGAGCGCTTCGCCGAGCTCCACCTGATCGAGGGCGACCGGGTGACGGCCACCGTCCCGACCTACCGCGGCGAGGGCCGCACGTTCCTCTGACGGACCGGCAGGCGCTGCCCTAGGCTGGCGTCCTGCCGCATTCGCACGTGTCGGACTGGGGGACGGTATGGAAGCCGAACTGGTGGCGCTGGCCACCTCGGGCGCGACCACGATGGTGAACCTGATGGCCACCAACCTGTGGACCACGGCCCAGGGGCGGTTCGCCGCGCTCTTCGGCCACCGGGCCGAGGCCGTGGCGGAGGAGCTGGAGGAGGTCCGCGAGGCCGGCGGCGAGGCGGAGGATCTGATCGCCGAGTGGCGGCCCCGGCTCCAGCGCCTGCTGGCGGCCGACCCGGCGGCGGCCGCCGCGCTGCGGGCACTGGTCGAGGAGTACGCCCCGCCCGCCGAGGCGCACGGCGGCGGCGTGCAGAACACCATCTCCGGCGGAGAGTTCCACCAGGCCGTCATCCAGACCGGCCACATCGGCAGCGTCAAGCTCTGAACGCGGCGGTGGCCGCCCACCGAAGTGGGCAGCCACCGACTGTGACTGACTGACCGTCAGGTCTTGGTGGTGCCGTCGGCGCCGCCGAGCGGGCCGCCCGAGTAGTCGGTGATGCTGGTGACGATGGCGTCCATCTGGTCCACCGAGGGGGCCTTGTCGGCGATGTCGAAGCCGAGGTGGATGGAGACCAGCGCCGTGTTGTTGGCGTTGGGGAAGACCACCGTCTGCACGTAGCCGTCGTTGCCCTGGGGGGCGTCGACCTTCCAGCGGATCAGGTAGCCGTCGCGGCCGTCGACCTTCACGGCCTGGTTCTTGAGCTCCTGGTGGCCCTTGATGTCGCCGTAGGAGTCCTTGGCGGCGGCGGCGATGTCCGTCTGGGCGGCCGCCTTGGCGTCGGTGCCCTTGAGGCTCTGGGTGGTCACGCCGCCGAGCGAGCAGGTGCCGGAGCCGCCACCCGGGCACTTGTAGCTGCCGACGCTGAGCGCGGCGAAGCCGGTGGCGGTGGTGCCGCCCGTCCAACCGGTCGGGACGGGGATGGAGATCCCGTTGATCGCGTCGATCGCCGGGCCGTCCGAGGAGCCGCCGCCCCGGCCGAGGCTGCCGCCCCCACCGGAGCCGTTCCCCGAACCGTTCCCGCCCCCGAGGCCACCGCCCCCGCCATTGCCGCCGCCGTTGCCCAGGCCGCCACCGGAGCCGTTACCGCCGCCGAAGCCGAACCCGTTGCCCCCGCCGTTGCCGTTGCCGTTGCCGGAGCCGCCGCCATTGCCCGAGCCGCCGTTGCCGAAGCCCGGGAAGCTGTCGCCCCCGTTGCCGTGGCCACCGCCGTTCCCGTTCCCGTTGCCGTAACCGCCGCCGCCGCCGCCGAAGTGGGAGCCGGACTTGCCGGCCGCCCGGGGTGCCGCCTTGGTGTCGGAGCGGCCGTCCATGGCGAGGAAGGTGATGCCGGAGCCGACCACCAGGCCGGCCAGGGCCGCGACGGTGGCGGCGAGGGCGACCGGGCGGGAGAGCTTGCTCCGCTTGCGGGCCGGCTGCATCGCGAGGACCTCGGGCAGCTCGGGGTAGCGGACCGTCGGTCCGCCGTCGAGCACCTCGCCCTCCAGCGCGATGCTCGGCCCGGGCCGGGTGGTGGCCGTCCAGCCCTGCCCGTCCCACCAGCGCTCGGGCCGGGGGCTGCTGTCGGTGTCCTGGGGGTCCGGGTACCACCCGGCGGGAATCTGCTCGCTCACGCCAGAGAATCTAAACGGATTTGGATAAGCGCGATATCAGCACACCGCCGTATCCGCCCTATTTCGGATGAGATTCCGGTGAGAACCGGGAACCCGCAGGTCAGAGCGGCCCCGCGATGATCTTGCCGGAGGCGTCGTCCGCCACGAACTCGGTCGGCGCGAGGAAGGCCGAGCCCGGCCCGGCCAGGAAGGCGACGGCCGCCACGGCCGGCTCGAGGGCGGCGCCCGGCCGCAGCCCGTACACCCGGATGCCCTCCCGGCCGTAGCTTCGGGCCAGCTCGGCGGAGAGCTCCCGGTCGGCCGGGTCGGCGGTGAGGTTCACGATCACGCCGTGGCCGTGCCGCCGCAGGTAGGGCAGCGCCGCCCGGCTGGCCGGCCCCGGTGCGACCGGGTGGACCGCGAGGTCCACTCCCCCGCAGGTCTCGTACGCCTCGTCGTAGAGCGCCTCGACCATGTCCGCGTCGCGGGGGTCGGTGTGCACGAACAGCCCGCCCACCGACCGGGCCACCGCCCGGCCGGCCGGTTCGTCCGCCTCGGCGCAGACCACCCGCAGGCCGTCCGCCGCGAGCCGCTCGGCCACCGCGCGTCCGAGGCCGCTGCCCGCGCCCGTCACCACCGCCACCCGACCACCCGGCCGCCGCACCACCCGAGACTCCCTCCGCCCGTCCGACCCGGCCGACCGTACGCCGAGCGGCGCCCGACCTGTCGGAGAGACGCGCGGAGTTTCGCAATCGGCCCACATTGACGGCGGCTCAGCTGACGTAGGGGGAGAATCCGGACATGACGACCAGACCGGTGATCGGCATCAGCACGCACCTCACCGACGCGACGTGGGACCACTGGTCCGCGCAGCGCGCCGTCCTGCTCCACGAGCGCTACCCCCGGCAGGTGCAGGCCGCCGGGGGCGTCGCGGTGCTGCTGCCGCCCGACGCCCCCGAGCACGCGCCCGAGGCGGTCGCCCGGTTGGACGCCCTGGTGATCGCGGGCGGCCCGGACGTGAACCCCGCCCTGTACGGCGCCCAGCCGCACCCCAGGACGGTGGCCAACGCCCCCGAGCGCGACCGCTGGGAGGCCGCCCTGCTGCGCGCCGCCCTCGCGGCCGGGCTGCCGCTGCTCGGCATCTGCCGGGGCATGCAGCTGCTCAACGTGGTGCGCGGCGGCTCGCTCATCCAGCATCTGCACGAGCCCGGCCCGCACCTGGGCAGCCCGGAGGGCTACGGGCGGCACGCCGTCCGCCCGGTGGCGGGCACGCTGCTGGCCGGGCTGCTGCCGGAGGACTCGGTCTCGGTGCCCACCTATCACCACCAGGCCGTGGAGCGGCTCGGTGTCGGGCTGAGCGTCTCCGCCCTCGCCGAGGACGGCACCGTCGAGGCGATCGAGGCCGCCGAGGGCTTCACCGTGGGGGTCCAGTGGCACCCCGAACAGGGCGCCGACCTGCGGCTGATGCAGGCCCTGGTGCGGGCCGCCCGCAGGCCCGTACCGGCAACGACAACGGTCACCAGTGCAGCCTTTGGATCTTCGTCCGAATTGGGGTTCACTTCCGGTGCGGGGCGGCTGCGGCCCGCGACGGAACGCTGACGCCCGGTACGAAGAGAGGACGGCGATGTCCGACCACGAGCACGACCACACCGACCACTCCGAGCATGCCCAGCACTCCCAGCACTCCCATGACGAGCACGGTGACCACTCCGGCCACTCGCACGGCGGCCATGGTGGTCACGGCGGTCACGGCGGCCATTCGCACGGGGTCGCGGCCGACGCGGACCGGCGCTGGCTGGTCAGCGCGCTGACGCTGATCGTGGCCTTCATGGCCGGCGAGGTCGTGGTCGGCTTCGCCGCCCGGTCGCTGGCGCTGATCTCCGACGCGGCGCACATGCTGACCGACGCCGCCTCGATCGTGCTCGCGCTGATCGCCATGCGGCTCTCGGCCCGGCCGGCCAAGGGCGGCTACACCTACGGGCTGAAGCGGGCCGAGATCCTCTCGGCCCAGGCCAACGGGGTGACCCTGCTGGTGCTCTCCGCCTGGCTCGGGTACGAGGCGATCACCCGGCTGCTCGACCCGCCGGAGGTCGAGGGCTCGCTGGTGCTGATCACCGCGCTGGTCGGGATCGTGGTCAACATCGGCGCCACCTGGTGCATGTCCAAGGCCAACCGGTCCTCGCTCAACGTCGAGGGCGCCTTCCAGCACGTGCTCACCGACCTCTACGCCTTCATCGCCACCGCCGTCGCCGGCCTGATCGTGGTCCTCACCGGGTTCACCCGGGCGGATGCGATCGCCTCGCTGATCGTGGTCGCGCTGATGCTCAAGGCCGGGATCGGGCTGGTCCGCGACTCGGGCCGGATCTTCCTGGAGGCCGCGCCCGCCGGGATCGACCCGGACGCCCTGGCCGACCGCCTGGTCGCCACCCCCGAGGTGGTCGAGATCCACGACCTGCACGTCTGGGAGATCACCTCCGGCCAGCCCGCCCTCTCCGCGCACATCCTGGTCGCCCCCGGCGGCGACTGCCACGCCGTCCGGCGCGGCCTCCAGCGCCGGCTGGCCACCGACTACCGGATCACCCACGCCACCCTCCAGGTCGACCACGTGGGCGAGGACGAGGACCAGCACCTGCTCCAGATCACCCCGGCCGGCGCCGCCACCGGCCCCGACCACTGCGCCGACTCCCACGGCCCGGTCCACCGGCCGGGCCCGCACGACCACTGAGGGCTCCCGTCGGCCGGTGTCTCCCGGTCGGCGGCGCCCGGTTGTCGGTGCGGTGCGGCATGATCTGAGGGGTGACCGCACCCCGCTTGATGCTCCTCGACTCGGCCAGTCTCTACTTCCGGGCGTACTTCGGTGTGCCGGAGTCCCTGCGGGCTCCGGACGGGCAGCCGGTGAACGCCGTCCGGGGGCTGCTGGACTTCATCTCCCGGCTGGTGGAGGACCACCGGCCGGAGCAGCTGGTGGCCTGCATGGACGCCGACTGGCGCCCGCAGTGGCGGGTCGACCTGATCCCCACCTACAAGACCCACCGGGTGGCCGAGGCCGCCGTCGAGGGCGAGGAGGAGATCCCGGACACGCTCGCCCCGCAGGTGCCGGTGATCGAGCAGGTGCTGGACGCCCTCGGGATCGCCCGTGTCGGCGTGCCCGGCTACGAGGCCGACGACGTGATCGGCACCCTGGCCACCAAGGCCACCGGCCCGGTCCGGATCGTCACCGGCGACCGGGAGACTGCAGATTACCAACCCGCGCGCGTCCTGATCGTGACAGGGGACAGAGACCTCTTCCAGCTCGTCGACGACGCCCGCGGCGTCCAGGTCATCTACCCGGTCAAGGGCGTCGGCAACGCCGAGGTCATCACCGAGGCCGCCCTCCTCGACAAGTACGGCGTCACCGGCGCCGAGTACGCCGACATGGCCGCCCTGCGCGGCGACCCCAGCGACGGCCTGCCCGGCGTCAAGGGCATCGGCGAGAAGACCGCCACCCAACTCATCCGCGAGTACGGCGACCTGGCCGGCATCCGCGCCGCGGCCGCCGACCCGGCCTCCAGGCTCACCCCCGCCCGCCGCAAGAACATCCTCGAAGCCGCCCCCTACCTCGACGTCGCGCCAACGGTCGTCCGCGTCGCCACCAACGTCCCCCTCCCCGCCTTCGACCCCACCCTCCCCCGCGAACCCCTCGACCCCATGGCCTTGGAAGAGCTCTCCGCCCGCTGGGGCCTCGGCACCTCCCTCACCCGCCTCCTCGACACCCTCGCCCACGCAGGGACAGGAGTAGCGTCTTGACATCGAAAACGACGTGCTGCGCGCATGGTTGAAGGAGATCCGGGTGAGTGGCTGTTGTCGTTTCGATCTTGAGGGGCGCGGGTCGAACGGGGGTCTCGATCGGGTGAGCGCAGCGGCCGCCGCGCATGAAAGCAGGGCCTCTTGGTAGCTCGAAGGGTGTCTACGCCAAAGAGCGGTCCAGGAGGCCCTGTTGTCCCACTTCTACGGCATCGCGGGACCGGGGTCCACTTCGGTCACTCTCGCGTGTGACTGCCTGGCACACCGGTTCGGGAACGCCGTCGACCACGGGGTCCGTGTGCGCCGCTACCCCACCGACATGTCCGATGCGGAGTGGGCGGTGGTGCGGCCGCTGCTGCCGGTGCCGGGCTGGCTGCGCGGGCGGGGCGGGCAGCCGGAGGCGTACTGCCACCGCACGATACTGGACGCGATCCGCTACCTCGTCGACAACGGAACGAAGTGGCGGGCCATGCCGGCTGACTTCCCGCCGTGGGACCGGGTCTACGCGTTCTTCCGGCGCTGGCGTGACCACGGTCTGGTCCGGGAGTTGCACGACCGGCTCCGCCGTAAGGCCCGCGAGCAGGCCGGGCGGGACCCGGAGCCGAGCGCGGGCGTGATCGACTCCCAGTCGGTCAAGGCGGACGCCGTCGTCGGCCGTGACAGCCGCGGCTTCGACGGCGGCAAGCTGATCAATGGCCGCAAGCGGCACGCCGTGGTCGACACCCTCGGCCTGCTCCTCGCGGTGATGGTCACCGCAGCGGACATCGGCGACCGCGCCGCCGCGCAGGTTCTGCTCGCCCAGGTGGCCGCCGCACACCACCGGCTGGCGCTGGTCTGGGCCGACGGCGGCTACACGGGCAGCCTCGTCGAGTACGGCTTCACCGTCCTCGCCCTGGTCCTGGCCATCGTCAAACGCAGTGACGACATGCGCGGCTTCGTCGTGCTGCCCAAGCGGTGGATCGTGGAGCGGTTCTTCGCCCACCTGATGCGAAGCCGCCGCCTCGTGCGGGACTTCGAACGGTCCACCGGCAGCGCGGAGGCGATGGTCTACTGGTCGGCGACGATGCTCATGACCCGCCGCCTGGCCCGGCCAAGGCCATCGCGAGCGTGAACCGGCCCGGCTCCGGCTCGACCAGCCACCCGCGCGCTGTCAGCCGCTTCGCCTTCGACCGCAACGCCTCGATCTTCGCGGGCACCGGGTCCAGGCCGAAGCAGGCGGCCATCTCCTGGCAGGTCAGCGGGCCTTGACCGAGACGGCCTCGGTCCGCGAGAGCCTGCACGATGCGCTGGTAGTCCGCCGACAGTGCCGACCGGGCCAGACCCGCACGCCACATCGGCACCACCGACTTCGGCTTCGCCGCTGCCGAAGATGCAGGCAGCGCCGGCGGTTCACCGCGATCCGACGGCTTCTCGACGGCGTCCGGGCCGGCGATGTCTCCTTCGCCCGGGGACAGCACCTCGCCGACGCGTGAACGGGCGATGACCCACTCGCTCCACTCCCGCTCGGCCGCGACCAGCTCGGCCTGGATACGGTCCGCCTCCTCCCGCAGCTCATCCACACGACGGCGAGCGGTCAGCTCACGCTGTTCCAGCAGCCCCACGACCGACGGCATCCTTGACCTCCACCAGAGCGACGACACGACACGTCACCACTCCCCGAGACCACCGCCCCTATGCCTGACCAGCGGAAACACAGCTCTCAAGTCAGGAAAGACAACAGCCACTGAGTTCAGCTGATACCCCAACTCCTACCGGGATGAGCCCGTATGCGACCGGCGGTGGCGGCGTCACCTTCGAGCGCAAGGTCGCCGTCCAGTACCTCGCTCATCTACTCCTCGGGGATGGCGCGGCTGAGCTGGGCGACAGTCGGTCTGTCGTAGGTGTGGACTTCCAGAAAGCGCCGGACCACTCCGCCGACGACCTTGTTATCCACGCGGCCCGCGCTGACGAATCCGGGCCGTCCCTGGTGCTCGCTATCGCCGTACGGCGAGCGCCCGACCTCGTGCAGAGCAACGAGCTGAGCAAGAAGCTCATCTGCACGCTTGTGCAGGAGGTCGTCAACGCGCCCAACGACGGGATTGAATACCGGGCGGCTCTGGTCGTCGCAGGTCGGCAGGACCACGCGGAGCAGCTCGCGGTCCTCGCCGACGAGGCCGTCAAGCAAAGAGACGCACCCAACTTCTTCGGGCTCGTCCGTACCCCCCGGAAGTTCCCCGTCGGCGTTCGAACGCGCCTCACTCACATCGAAGAGCTCGTCAAACACGCACTGACTACGCTCAGGGCCACCGAGCCCAGCCCACAGCTCGTCGAGCAGCACACCTGGGAGCTGCTGTCGCGGCTCACTGTGCTCATGCCGCGACTCGAAACTCCAGACGACTTGGACTGGGCTCCAGTAACGAACTCCTTGATCCCTGTAGCCCGCGGCGCTGACCTCTACGGGGCTACGCGGTTGCTGGAACGGCTCATCGCCCTAGCTGACGAGTACCAGCCGAAGGCGGCCACCGTCGACCTGAGTCTTCTACGTCGCGATGCACACCAGGTCCTCGACTCGACCACGCGTCGCCATCGGCAGGGGTGGGGGGCGCTCGGCCACCTTCATGAGCGTGCGCTTGCGTCCGTGCGCGACGAGATCGCTGCCGAGGACGGCAGTCGCACGGTTCGCCTTGATCGGAGCGATACGGCAGCTCAGCTGCTCCAGCTTGTGACGCCCTCTGCGGCAGTGGTCGCCAGCGGTGAGTCCGGCGTGGGTAAGAGCGCCTTGGTCGTCCGCACTCTGGCCGCTGCCGCACAGGACGCCGACTCCGTGCAGGTGGCGTGCATCAACCTAAGGCATCTCCCCGGCACCACCGTCGAGTTGGAGGCTGTACTCGGCACCTCGCTCACTGCGCTTCTCGGCGAGCTAAGCGCCCCTCAGCGTCTGCTTGTCATCGACGGCGCGGATGCGCTCGCCGAGGGCAAGCAGGAACTCTTCCGCTACCTAATCGACGCGGCTGGTCAGGCCGACGTCAAGGTTGTCGCCATCACGGCGAACGATGCCCGGCAAGTCGTCCATGACACCATCAGTGATCGCCGCGTTGGGGAGGTCGCCGGCTTCGAGGTACCACTACTGACTGACGCCCAGGTGACCGAGGTCGCGTCAGTATTCGACGAGTTGTCGGCTCTCGCAGCGGACCTTCGGTCACGCGAGCTGTTGCGCAGACCCGTGGTGGTAGACCTGCTCGTACGAGGGGGTGTAAAGGCCACACCTCTCAGTGACGCCGACGCCATGCAACATGTGTGGTCGCGGCTGGTGCGGCGCCAGGGCTATCCCGAACGTGGCATCCCTGATGCCCGGGACATTGCGCTCCTCCGCCTGGCCGCCCTCGAACTCGGCCACGGAGACGCTCTGGAGGTCGTGGGAGCGATCGATCCCACCGCGCTCGCCGGCCTGCGCCAGGACGGCCTGCTTCGTACGGACGCGGACGACCCATTCGCCATCGGCCCGCAATTCGCACACGACGAGGTACGCCGGTACGCGATAGCCCGACTCTTCCTCTCGGCGGGCCACCCCACTACGAAATTGGTGGAAGCCGGTGTGCCGCGCTGGGCGCTCGGTGCCGCACGGCTTGCCTGCCAAGCACTACTGGCTGGCCCCGACACCCCGAAGTCCCCTCTGCGCGGCAGGTTCGCCCGCTTGCAGCAGGCATTCGATGACCTGGTCGCGGCAGGCCACGGCGACCGCTGGGGGGACGTACCCGGTGAAGCGCTCCTGACGCTCGGAGCGCCCGACCCGGTACTGCGCGAAGCGTGGCCGATGCTGCGCGCTGAACCTAGCGCTGGCCTGCGGCGACTCATTCGTCTCGTGGACCAGCGGCTGCACGATGAAGCAGGCCTGGTGCGGATCATCGCGGTCGAGCCGCTCATCGCCCTGCTACTCGACGACGAGGAGCCCTGGCGGCAAGGCAAGCACGTGCAGGACATCCTGCGGGACTGGCTCCACGCAGTCATCATCGCGGGCACACCTGCTGGTTATCCGCTGCGGGTGAGGCTGCACGACCGTCTGGTCGCCGCCTGCGCGGCAGCCGATCGCCGGCTCAGCGACGAGCAGGCAGCTACGGCTGCGGCGCAGGCGGCATTGCCGCCGGAGGAACTCGAAGCCGAGCGCCAGTTCCTAGAGAAGCAGATGCTGCGGTTCACGGGAGGCAGCCGTCGGCACACCCAGCGTAGTGCGCGCCATGAGCTTCCCCGTGAGATCACCGACGAGCTCATGGTCGAACTGCTGGCGCTGCTCGGCCCGGATCTCGGCGAGGACGGCGAAGCTGTCCTGCGTCGAGTTGCGCACGATGCGCCGGCATGGGTCGGTCCCGCTGTCGACGAGGTGCTGACTGGCCGGGCGCTCGCGATGTATCGGCGCGGTTTCCTCGCTGAGTTGAGTGTGGCCTACTACCTCAACGAGGACGAAGACGGGACAGGATTCCACCAGGATGGCATCCGACGTCATCACGCTCGCGGGCTCGGCGTGACCCCTCTTGCAGCCTGGTACCGCGGTCCGTTCATGTCGTTGTTCCAGACGGACTTCCGCAACGGCGTCTCGGTGCTGAACCGAATGCTTAACCACGCCGCACTGGCGCGTGCACGCACCCTTGCTGGTCTACAGCGTCAGTACGGCGCCCCGATCGAGGATCACGCCCTCGACGACTACCGCGAAGAGCTCGACGTCGCAGGGGTTCGCCGGACGTACGTCGGGGATGAGCATGTCTGGCTCTGGTACCGCGGGACCGGCGTCGGTCCTCATCCCTGTATGAGCGCGCTGCAAGCGCTGGAGCAGGTGTGCGACCAACTGGTCGAGGCGGACATCCCCCTGGCCACACTGGTCGCCATCTTGCTCGAGGACTGCGCGAACCTCGCGATGGTCGGCTTGGTTGTCGGCCTGCTCGTTCGCCACTTGGAGCGCGCTGACCGTCTGCTGGATCGCTATCTCACCGAGCCGGTGATCTGGCATCTGGAGTTCGGACGTGTCGTCCATGAAGCGAGCGGCTTGGGGGCATCCTCCGATGGCTTGACGGCTCCCGAGCGCCGACGCTGGTCGCTGCGGGAAACGGCCACGATGATGGTGCTCCGCGCTGACGACCAGCGCGCGGACGAGTTGCGACTTCTCGGGAGTGGGCTCATCGCAAACGCCAGGCGACTCTTCGAGGAAGAGTTCGGCGAGAGCGCTGAGAGCACGGTCCAAGAACAGCTTGCCACTGTGCGTGCCTGGGCCAGTGGCCTCGACCGCGGTACCTACCAGGCGCAGCAAGTGGAAGGGGGCCTGGAGATCCAGAGCACGCCCCCCAGTGACGTCGTTGAAGCGTTGCAGGCCAGGAACGTCGAAACGGCACGCGCTCGGGAGGCAATGCGGCTTAACGTCCGCTACTACGTCAATCCCAAAACCGGCAAGGCCGAAGCCATCGACTCGGACGAATTGGTCGCCGACCTGGCTGCGGCCCGCGAACTTCTGGAGAACCCGCCCGACCTAGGCCCCAGCAGCCAGTGGGACGCACCTGCCGCAGTGGCCGCGACGGCGCTCACAGCAAACGTCGTGGATGGCGTCGACCTGCCCGTCGATGCCCTGCGCTTCGCCGTCGACACACTCCTGCGCATCGGGGAGGACGCAACATCACCGCGTCAATTCGACTCCGAGGAAGCTTACTTCGAACAGGGGGCGGACCGCTTTGCTGCACGGACGCTACCACTGCTTCTTACACCCGCCGCTACGCCGCTCCGCGCCCAGATTGACGGCAAGGACGGCTCCACGACGTACCGTCAGGCCGCTGCCGCGGCAAGCAAGCTGGCGCGTTCCCTCCCCAACGAGGTTCGTGTGAACCTGGCTCGCGGCCTGGACCATGTCTGGCAGGCTGCCTGCACAGCCGGAAACCGCAGTTGCCACCACGAAACAGCATTCGAGCTGGCGGTCGAGACGATGCGTGACTGCACCTTCGGTGACTGGGACCCGGACAGCGGCCGGCGAAAGGTCACCGCTCTCGAAGATCCCATCGCGCACTCTCTGGCCAGAGCGGCCGCCGACTGCATCTACGAAGCCCGCCTCGATGGGGCGATCAGGGCCCTCGGCCCGGCAGCGGCAGCGTCGATCTGCGTCTCGGCCTCCGCTCGCGAACTCCTCGCCGTACTCCTCGCAACGCACCGCCGCTCGTTGCTTGCCTCCGAGGACGATATGGACAGTCGCGGCACCCACGCCCTGATCGCGGCGCGGGCACTGCTCGCTCTGGCGAGCACGGGCGAGGACGCACCCGTCTTCGAGCACATCGACGCCTACGCCGACAACCCGACGCTGCTCGGCAGCTTCCTGGGCGCGCTGTCTTCCGCTGCCGAGGAGTCCGCGGACAGGGCGGCCACCGCACGGCGGATGTGGCCGACCGTGGTCGCCCATGTGATCGCCCTGCAGGCCTCCGGACACACGCCCTTCGAAGGGCGGCACGAGTACCGCTCCTCCCTAGCGTCACTCCTGCCCAACCCTGCCGCCGAAGTCGCCTACCTCTACCGGGAAGTTCAGAGCAAGCCCATCGTCTGGTGGGAGCCACTGGCCTGGCAGGACACCGTCGCCCAGTGGTTGCCCATGGCCCGGGGCCACGCCGCATGCGTGGATCAGCTCATCGGCTTCATCAAGCCCCTGCCAGCCGAGAACCAGGTCCACGTCGGGCTTCCGTGGGTGGCGGACCTTGTCCTCGCCGACCCCAGCCGAGTAGCGAAACGTACCTATCTACTCCCGTCATGGCTGATCGAACTACGCCAAGCCGTCGCCGACGCAGGTATGACGGCCGACTGGCAGCGCGTTGTCGATGCGCTCGTAGTTGCTGGGGTCTCCCGGCTCGCGCCGTACTCCGAGTAACCCTGCGGGATTCAACCAAAGTAGGCCTTCACTCGTCTGATACAGCTGTGCTCTGCGGGCATTGTCGCGCCCAAACCCGGACTGCGGGCATCTGGTCGCCCGCAGTGGAGCGAGCGGGCAGCCTCGGGGTGTCGCGCGTCAGACTTTGTGGCAGGGCTCGTTTCTTGCGGGTCCTGCTGCTTGAAGGAGTCTGATCGATCATGATGAGTGAACCGTTCCGGGTTCGGTAGAGGCTCGATTTCGTGTAAGGATTCGAGTCATGGCACGTCCCTCGTCCTACCCGCCTGAGCTGCGCCGTCGTGCGGTGCGCATGGTCGCCGAGGTCCTTGGCGACTACCCGAACGAGTCGGCCGCACTGCGGGCCGTCGCGGAGAAACTCGGCATCGGCTCCGCCGAGACGTTGCGCAACTGGGTTCGGCGCGACCAGGTCGACTCCGGGCAGCGCCCCGGCACGACCACGGAGGAGTCCGCGCAGATCAAGGCGATGAAGAAGGAGATCGCCGAACTCAAGCGCGCCAACGACATCCTGAAGGCCGCGGCGAGTTTCTTCGCGGCCGAGCTCGACCGGCCACATCTTCGCTCGTAGCGTTCGTCGACGAGCACCGGAACCGCTTCGGCGGCGTCGAGCCGATCTGCCGAGTGCTCACCGAGCACGGCTGCAGCATCGCCCCCTCCACCTACTACGCCTTCAACAACCGCACCCCTCGGCCCGTTCGGTCCGAGACACGGCCCTGAAGGAGCTGATCAAGGAAGTCCACGACACCAACTACCGCGTCTACGGCGCCCGGAAGATCTGGCGGGAACTCGGCCGCCAGGGCCACCAAGTCGCCCATTGCACCATCGAGCGCCTGATACGCGAACTCGGCATCACCGGCGCCGTGCGCGGAAGGAAGGTCGTCACCACCATCCCCGACCCCACCGCCGAACGCGCCCCGGACCTGGTGGACCGTCAGTTCGTCGCCGACGCGCCGAACCGCTGCTGGGTCGCCGACTTCACCCACGTGAAGACCTGGTCCGGCGTCGTCTACATCGCCTTCGTCGTGGACACCTTCTCCCGGCGCATCGTCGGCTGGTCCGCCGCGACGACGAAGGAGACCCGGCTCGTCCTGGACGCTCTGGACATGGCCCTTTGGCAACGCGACCGCGACGGATTCCCCCACCGGAAAGGCGAGTTGATACATCACTCGGACGCCGGATCGCAGTACACGAGCTTCCGGCTCGCCGAGCACCTGGACACCGCCGGCATCGCGGCCTCGATCGGATCCGTCGGCGACGCCTACGACAACGCCCTGATGGAATCCACCATCGGCCTCTACAAAACGGAACTGATCAAACCCGGCCCACCCTGGAAGACCCTCGCCCAGGTCGAGCTCGCCACCGCCGAGTGGACCGACTGGTACTGCCACCGCAGACTCCACGGTGAGATAGGCCACGTCCCGCCCACCGAATACGAGACCACCTACTACCACACAACCACAAAACCCCAGCTCACAACCACAACCTGAGCCCTCTACCGAACCCGGAACGGTTCAGTATGCCGTGAAACGGGACTGCAGACGAGCAAGGGCACACTCCGCTGAAGTTCCCCCGTGATCCTGGAAACTCGTTCTCATGCTGCGAGGGTGTGTCGTTGTCGGGTCTCGTGTGGGGTGAGGTAGCTCCAGATGGGGTGTTTGCGTAGTCGTCGGCGGTTGTAGAAGGTCTCGACGAAGGCGAAGACGTCGGCGCGTGCGGTGGCCCTGTCGGGCCAAGTTCGGGTGCCGATCTCGGCTTTCAGTACTGCCCAGAAGCTCTCGGCCGCGGCGTTGTCCTAGCACGAGCCGGTGCGTCCGGTGCTCGCTCTGTCCCCAACTCTGATGCTGTGGTGCGGAATTGGGTGGAGGTATACTCGCTGCCGCGGTCGCTGTGCGCGATGCAGCCCGCCTCCAGGCGGCCTCGCGCGTGGGCCATGCGCAGGGCGTCGACGACCAGGTCGGTGCACTGGTGGCCGGCCATCGCGTAGCCGACTACCTCGCGGGAGGCGAGATCCAGCCAGCAGGCAAGGTAGAGCCGGCCCTCACCGGTGGGCAGGTAGGTGATGTCGCCGACCAGGCGGGTTCCTGGTCGGGTGGCGGTGAAGTCACGGCCGATCAGGTCCGGTGCGGGGCAGGCCTGTTTGTCCGGGCGGGTCAGCGAGCGGCGCCGGCGGCGGATGATTCCCGCGATGCCGCGTTCGCGCATCAGCCGCTCGATCCGCTTGTGGTTCACCACGTGTCCCTGGCGCCGGAGTTCGGCGTGCACGCGCGGCACGCCGTAGGCGCCCTTGGAAGCGAGGTGGACCGCGGTGATCTCGTCGACGAGAGCGTCGTCGGCCCGCACGCGGGCCCGCCGTGCTTCCTGGCCGCCGGCCCAGGCGTAGTACGAGGAGCGGGGGACGCCCAGGACGCGGCAGAGCAGGGTGACCGGGTAGGTGGCCTTCTCCGCCGCGATGAACCGGTAGGCCTCGCTCGCCGGTCGCTCTCTCACGCGAAGAAGGCCGTGGCGCACTCAACCCGTCAGCGCGACAGAGGCTCCAGCCTATCGGCCGGCGTGTCGAAGTCGAGGGTCTTTCGGGGCCGTGTGTTCAACTTCAAGGCGATCTCGTCGAGGTCGACCTGGTCTCGCTTGACCCAGCTCCGCAGGCCCTCGGGGCTGCCCCCAAGTCCCTGGCCACCTCCGTGACCGTCTTACTGGACGAGCGGGCCAGCCTCACGGCGTCCCGCTTGAACTCCTCCGAATACCGCTTGCCCTGTTTGTTGCTCACCTGGCTCTACTTCCTCTGGAACCTCACGTCCCAGTCTCCAGGTATCCAGGTCCACGGGGTAGCTTCAGAGCACCGGTTTCTCCCACGACCCATACAGTCGGCCGCAGGACTGGGGCTCTGAAGGCTTCTTGACATGCAGTCGGTGGGCGCCTCGTACGCCATGCAACTTGCTACGCCTTCGGTCCAGCCTCAGGGACTAGGGCACGTATTCGGTTGTGATCACGGGGCGGTTTTGGTGAGGTCTTTGATCCAGATCATCGCGCCGCGGAGGTGGAGGCCGGCGAGGTAGCTGCCGGGGGTCTTGTCGTATCGCGTGGCGATGCCTCGCCAGGCCTTCAGCTTGTTGATCAGGCGCTCGACGGTGTTCCGCTCCCTGTAGAGGTCGGTGTCGTGGCTGACGGGCCGGCCGCCCTTGCTGCCTTTCTTCTTCCGGTTGGCGGCCTGGTCCTTCTTCTCGGGGATGACCGCCTTGATACGGCGACCGCGCAGGTGGGCGCGGTTGGCGCGGGAGGAGTAGGCCTTGTCCCCGGCGACCGCGTCGGGCCGGGTGCGGGGGCGGCCGACGGGCCCGCGGACCCGCACCTTCTCCAGGACGGGGATGAACTGCGGGCTGTCGGCGGCCTGCCCCTCGGTCAGAATGAACGCCAGCGGGCGGCACCTGCGCTCGCCGGCGACGTGGACCTTGCTGGTCTGTCCGCCTCTGGAGCGTCCGAGCAGGGCGGCCTTCAGGCGGAGCCTTCGCCTGCGTCGGACGCGTCGGAGCTCGTCCCGTTCCGGGTCGTGTGCGGTGTCCTGTCCGTCTTGTCCCTGCGGGCCGCCCCTTTTTGCCGGGCCTTCTCCGCCTCCTCGGCGGCCTTCTCCAGGTCGGCGAGCGTGTCGGGGTCAAGGTGCATCCCGGCGGCGTCGTGGTGGGCCCGGATGGTGGTGGAATCCACGCTGACCAGCGAGAGGTCCACCTCGCCCCGTCTGGCGGCTTCCGTGATCGCGCCCTCCAGCAGGGCCTCGAACACCCTGGCGTCCCTCCACTGCCGGAAGCGGTTGTGGACGGTCGACCAGGCGCCGAACTCGCTCGGCATCTCCCGCCACTGGCCGCCCGTCCGAAACCGCCAGATCACGCCCTCGAACTGGCGGCGCAGCCGCTCGGGGTACGGGCCGTACTCGCCGATCGGCAGGTACGGCTCGATGAACTCCCACTCGGCATCGGTCAGTTGCACACGCGTCACACAACACGATCTACCGGATCAGGCACGAGCGCGAGGGCGAAACCCACAAAGTGATCACAACCCGATACGTGCCCTAGTCGGTCGGTGTCCGACAGGGTGAGTGCGACGTGCACTCCAGGGATGGGTGGCGGGTCGTTGTCGACGACGACGATCTGCAGGTCTTCCCCGCTCTGCTGAGCAGCGGCCAGCAGGGTGGCGTACATCTTCTTCAGCCTTGTGAGATCGATGCCTTCATGGCCGACGTTGCTGCTCACGCCGTCGATGATCAGTAGGTTGGGCAGGATGCTCTCGGGGTGTGCCAGCGCGACGAGTTGGTGTGCCAGGGCATGGGCAACGTTGACCATCACCTCGACGCCTTGTGAGCTGAGTTCGGAGAAGGAGCGTCCGTCGACGATGGGCAGGTAGTTCTTGCGGCTGATGTAGGAGCCGGGGCGGGGCTCGACGCGCGGGGCGTCGAAGGACAGCAATGTGTTCTCGAAGGCGCGGTCAAGGTCGGCCATGCGCCCTTCCGCCACTGGGTTGCGGTGGCGGGCGGCGTCCAGACGGCCGATCAGGTCTTCGCGCTCCCGCTCGAGTTCGGCGACCCGGCTGCCCTGGTTCTGCAGGCGCTGATGAAGCGCGAGGGCTTCCCCGATGCGCAGGAGCTGCTCTTCGAGCCGGGCCTGGTCGGCGCCGAACCGGCGGATGCGATCGACCTGATCGGTCAGGAATCCCTGCGTCAGGCGGTCCAGTTGAGCACCGAGCTCGGCCCGCAGGGCGGCCTTCGCCTCGCGGGTCTGCTGAAGCAGTAGGAGGCGTTCCCGACTGCGGGCGATCAGCTGGTCTGTCTCGGCGACCTGTTCGATCACCCGGTCCTGCTCGGAGACCAGCGCAGTGGTGGGGATCACTGCCGGAGGGTTTTGCAGGCAGAGTCGGCAGGTGTCCTCTCCTCCGCGCTCCGGCACGTCGGATCCGCACCGAGGGCAGGTGTGGAACTCGAAGTCGCTTAGCAGGCGTTCGGCGACGAGCGCCCGGGTGATCCTCCGGCTCTGCGCGACCAGTTGGTCTCGCAGGCCGACGAGACGGGCAACCGTCGCCGTCTCGGAATGCAGAGCGGTGTCGGCCTCCTGAAGGTCAACCTCGGATGCCGCGATCTGAGCGCGCAGGCTGACGGTGGCCGGCTCGTCGAGGGTCCGGTTCAGAGTCTGCTCCGCCTCCCGGGAGCGGGCGAGCTGCTCGATCGCCTGGGACTGCTGCACCTGGAGCTGCGCGGAGGAGGAGAAGGAGCTGGCCTCCAGCACTCTCTCCAGCATCTTCGCGTCAGCGGTCAGTGTTTTCAGCTCGACGGACACCTTCCTCAAGTGCTCGCGCAGTTCGATCGCCTTGGGACTGAAGATGCCGTAGTAGATCTCGAAGACGAACTTCCGCTTGATGTCCTTGTGGTAGTTGTCCGGGGTCCCGAAGACCGACGAGTCGATCTGGTCCTGGCGCAGAACGCAGTACATCAGGTAGTCGTTGATGGTCACAGGGACCAGGGGGCTGGTCTCGTCGGTCGGGGCGCGCGGCACGAGGACCTTGGGCAGCCCGAGCATCTGCAAGTACCAGTCACGGAAGGTCAGGTTGTAGCCGGGTTCCAGGCGTGCGGCCGGCAGACGCCAGGCCTGCTCCGCGCCACCGATCTCAGCGACATCGATCTTCGCGGTGTCGGTGGTGACCAGCGGGCGCACGATGCGAAACCGGCGATTGCCGATCAGCACGGTGCCGGCGGTGGTCCTGCCTTTGAGTTCGGGGACCACGTTCACGTCGCCACCGAGCAGGGCCCGGAGGCAGCTGATGGTCGCGGTCTTGCCTCCGCTCATGGCACCTGTGATGGCATTGAGGCCGGGCGTGAAGTGCACGGTGCGGGTCGTGCCGCTGATCGTCAGCTCTTCGATACGCAGTCTCACAGGTGGGCTCCCCAGCTCGTGTTGACGATGTCGGGGAATGTCTCGTAGATCAGGTCTTTCAAGGATGTTCCCGTGAGGTTGAAGTAACGTCGCAGCAAACGTGCCCGCTCTCGTACGGCTTCCCAGCTGTCGGTTGCCGCCAGTGCGGCGGCGAGCTGGTGTCCGTCGGGGGTCACGGCGTAGGCGGCTACGCTTCCCTGTTGCTGTGTCGTGATAAGCCCCTTGCCGATCAGCGCTCCCAAGAGGCCGTAGTAGGCGGGGTCCCACGGGCCGTAGCGGTAGCGAATCATTCCCTGCTCGATGGCCCCGGTCAGCCAGGGGTTCTCACCCGCGGCGATGCCAGGTGCACGCAGTTCCATCAGCGTGGTGAAGCGGTCGGGGTACCGCAGCAGGAAATCCAACTTGGCCAGCTTCATCCGACCCTCGACCCCAGCCTTGCCAAAAGCATCGATCAAGATCAGCAGGCGGGCCTGCGCGTCCACCGAAGGTGCGCTGCCAGCCGTCGTTGACAGAGTGTCAGCCGTCACTGGTCGCCACCCCCCAGCCGAAGTGGCACTCGTCCGACACCGAGCAGGCCCGGCCCATGAGGAGCAACGGGTCCTTGGCGTAGAGCGGCCGGCGGTCGAGCTCGCTGGCGGTCGAGTTGATCTCCTGCATCAGGTCGTCCCAGATGTGGTCCGCGGGCCGGTGGCCCCGGTCTTGGTGTCGGCGGGCGATACGGGTGGCAGTGATCAACAAGCGGGTGTCCAGATCCTGCTCGACGCGGGGATCCTCCGGCCAAGCGCCAAGGGCCAAGTCGCTCAACCGCCGCCCGTCCGCCTCGGAACGCAGGAACTGCGCCTCGTGGATCATCTCCTCCGAGGCACCGCCACGACGCAATTTCCGGACAAGGTTGGTCTCGACCGCGTCGATACGCTCCGAGTAGGCAGCCAGCAGCACGTGATCCGGGCGCCGCAGGCGCTGTCCAAGGTCGTACACCGAGCTGGGTGCCAGCCGCTTGCGCAGCAGAGCCTCGCTCGGGGGTTCGACTCCCAGCTTCTCCTTCCAGCTGGCGCCAGCCTGTCCCTGCATGGCCTCATGGACCCGATTCAAGACCTCCAGGTATACGGCCCGCTGCTCGCCGACACTCACGGCAGGTGCCAGCTCGGTCAGACTCGCCAGGCTCTGATCGTCGATGTGCTCACGGCGTGGCATCGTTCGCACTCTGACGAACGATAGACATGCGGAAACATCCGCTTCTTGCGCTTTGAGGTGCTTCGAGACGCGAGCCAGGCACTTCGGGTGGTCCGCGCCAGCTCCTCGTGCAAGGGCCGTGAGCGCATCGTCCGCTGGGTCGAGAAACCCCTCGACGGCCACGGTCAGCAGGTACTCAAGCCCACGGGCACGGACTGCCAAGTAGGTCCGCCACAGGCTCTTCAGGGCACCCTTGGCGATGATGTCAGACAGGCCCCAGGGAGTTGGATCGTCCTTCGTCTTCACCTGGAGGAAGTCCCACAGCACATCAGAGCGATTCGCGGGGTGGTCAGTTGCGATGACGACGTCCTCGATGTGCTCGCACGTGACGTGGTGAATGCTGCCCCCGTCGCCCAGCATGGCGATCACGTACCTTGCGGCCACCTTCTCCTGGTAGGTGAACCGGCGCAGGGTGACGGTGCCGGTGTTGTCGGGCGCCGGGATGTCGAGCGGGTCCGTCACGCGCCCCCAATGGGTCTGAAATCAGGAACCTCAGGCTAGAACCGGAGGGGAGGGCCGTCGATGCTTGTGATGAAACCGTAAACGATCAGCGGCACCCAGTCGCCGCCCGAGCCCCGATCGCCGTCACTGTCGGCTCCATCTGGGACAGTCTGCAGCAAGCCTGTGACCGCGACGAAGGCCAGACTGGCTTCAGGTAGCGGCAGCTGGGTTCCGTCCTCTTTGACCGCGATGAGGATCGTCTCCGGACCGTGGGCCGTCGACCAGCTGCACGATCGCCTCTGGGCAGGAGTGGCACTGCCCTGCCCGACATGCTCCTGCACCCCACCCCAGACGAAGGACACGAACCGCACCCGGCCGCAGGGTGGCGGCCGTCGGCGTCACGGGGACCGGGAAGTGCTGGCCGCGATCGTGTTCGTGGCCACCTCGGGGTGCACGTGGGCCCAACTGCCGCCCTGCTGCGGGCCGTCCGGTCCGACCGCGCACCGCCGTTTCACTGAGTGGTTGCGACCGCCGAACGTGCTACAGCGGGATGAAACCCCAGACTCCCGCACAGATGCCTGACGGTAGAGTGAGATCCATTCTGTAGTGGATTCAGCGGCATCGCAGTACAGGTAGGGAGGCTGGCGTGGCTCAGGAGTCGAGCGAGCTCGAAAGCCGGTTCCCGGACCTGGCTCTCGCGTCAGCCAATTTCGGATTCCTGCTTCCCTATGAGCCGCTACTTGTTCTCCACGGTGCTGCATGTGAGGCGCGTGCATCGGCTGCCCCCGCCGACTCAGTGGCGGCGGCACGTCAGTTCGGAGAGGTTCTCGCCGTCAAGCTCGGCCAGTTGACCGGGGTGCGGCTGCCCGTGGGCGACCAGTCGGCCCGCCTGCAGACCCTAGCCCGCGCCGGGGTGCTCACCGCGCAGGTTCTGGCCGCGTTTAAGGATCTTCACGGCTTCGACGGCGGCGAACTCGACGAGGAAGAGACAGCGGCGCACCTACTCGACTGCTGCTTTACGCTGGCCGTCTGGTTCTTCCGTGCCCTGACAGGCGACGCGGAGCCGATGGCCTTCGTCCATACCGAAGCGTCCGATCTGCGCGTTCTGGCGCAGCAGGTCGCAGTGCTGGAAGCGGCCCTGCCCCGTTTGCGCCGCGAGTTCGACCGCGTCGCGCCGGCGTCCCTGTCCGCCGCCGAGCGTGAGCAACTGATCGTCAGCGCGCGCGATGCCTCCTACGAGCCGCTGCGGGAAGCCGACATTGCCTCGGGAGTGCAGCGCAGGCTCGCCAAGGCGGGATGGGACGTCCTGGGCGCAGGTGCGGAAGATGAACTCAACCGCTCCCTCGGCTGCGTCCTGGTAGGACCCCGCCTGGCCGGAGGACACCGCGCCGACATGCTGCTGACGGTCGGCGGCCAGGTGGTCGGGATCATCGAGTGCAAAAGGGACGGCACCGATCTCACCGACGCCATGGAGCAGGCGGGCGCACTGGCCGAGGCCGCCACCGGCTCCTCGCCGTGGCCTGTCTGGCGCTCGCCGCTGCCGTACCGGTATGTGAGCGATGGCCGACGCCTGCTGTTCTGCGACGCCAATGAACCCGAACCCCACCCTCGCCTCGTCAGCGGCTTCCACCAGCCCCGCACGCTGGCCCGCTGGCAGCGCGAAGCGGAGGCGGACGGTGCGGCGCCGACCTACCGGGCCCGCCAGGCCGCCTACCTGCAGCGGCAGGACGAGGGGTTCGACCAACTGCGCATTGCCCAGCGCCGGGCGGTGCGGGCCATCGAGCAGGCCCTCGCGGCCGGTCAGCGGCGCGCACTGGTGCAGATGGCCACCGGCTCCGGGGCGAGCTTCACCGGGGTATTCACCGCCTACCGGCAGCTCCACTACGCGCGCGCGGGCCGGATCCTGTTCGTGACCGACCGCAAGCTCGCCGTGCACCAACTGATCGCTCAGCTAAGCCAGTTCAGCATGCCGGACGGAGGGCGCCCTCTCGATGACGTGTACCACGTCCAGGAACTGACCGCGCACGGCCTGGCCCCGTCGGCTTCGGTGGCCGTGGCCACGGTGCAGCGTCTGTCGGCCATGCTCGCCGACACGCCAGCACCCGAGGACGGATCCGAGAGCGTGGCGGCGTACGAGACCGCCGAACGGCAGGCGCATTCCGATGCCACGCCCCTGGAAGTGTCCTACTGCGAGGCGCTGCCGCCCGACGCGTTCGATCTCATCATCGTCGACGACTGCCACCGCGCGCTGTACGGACAGCGGCGCGCCCTTCTTGAATACTTCGACGCTCCCGTCGTCGGATTCAGCGCGACGCCGACCGCTACCGTGCTGGGATTCTTCAAGGGCAACCTGGTCGAGTCCTACAGCTACGAACAGGCCGTCGCCGACGGCGTCGCCGTGGACTACTCCCTCTACCAGATCCAGGTCGATGGCGACCGGCAGCCGGCGTTTGCCACCCCCGTCGACGCGGTCGGTGTGCAAGCCCGCAGCTCGCGCCGCGCCCGCTACGAGGACCTGGACGACGAGCTGGCCTTCACCGCGGGGCAGGGCCCGGCAAGGGCTGTCCCCTCTGAGCGCCTGGCCAAGGTGGTGACGGCTTTCCGTAACGCGCTGCCGACCCTGTTCCCCGACCGAATGCAGCACGGCAGCGGGCTCCTCGCGGTCCCCAAGACCATGGTGCTGGCGCAGGACGGACTCCATGCGGACGAGGTCGTGGAGCGCGTCCGCGACGTATTCGGCGCCGGGGACGTCTTCTGCCAGCGGATCACGCCGCGCGACGCTTATGCGGCGGAGCTGCTGCGGGAGTTCCGCACGACACCGCAGTTCCGGATCGCGGTCGTGACGGATCTGATCTCTGGGAACAGTGACATGCGGGTGATGGAGTGCCTGCTGATCCTGCGCGAGGTGCGCTCCGCCGCCTACTACGAGCAGCTACTGGCCATGGGAACGCAGACCATCTCGTCCGCGGAGTTGCGCGCCGTCACCCCGGGAGCGGATGCCAAGGCGCAGCTCGTTGTCGTCGACGCGGCGGGCGCTTCGCGTCACCTCCAGCCGCTGGTCAACGTGACGGATGCATCCGGGCAGAGGGGACGGGACGCCTTGGAGCGCCTGCTGCACCGAGCCACTGATGGCCGGGCAACGCCACAGGAGACAGCCGAACTCGCCGTCCGGCTCGCCCGGCTCATCCCCGCGCTCAGTGACGCCGACGGCGCCGAGATCCGCAAGCTGGCGGGCCGGCCTCTGCAGGAGCTGGTGACCCGTCTCCTCGACTCGGTCAACTCGGATCACCTGGCATCGCTGCGCCGGGCGGGAGGCAAGAGAGCCGTCGAGGATGAGCGGCGCGAGGCCCTCAACCCGCTCACCGAGGACCTCCAACTCCAAGAGGTGCTGCTCGACCTGTACGACCGGCCGACCCCTGCTCCGGGAACGACATCCGGCAGCCGGGGTCGCCGTCAAGACACGACGGTGGGCCGGCGCCTGGACGAGTTCGTCGAGCGGTCCGGACCCTTTAACTCCGCCCAGCTGTGGTGGATCGAGAAGATCGCGGATGTGGTGGCCACCGAGACGCGCTTCGACCCGGCGTATCTCGACAGCGTCCCCTTCTCGGCGCGCGGCGGCACGGACGGCTTCCTTGACGCCTTCGGGCCCGACGCCGCTATCTGCCTCCTGGACGAACTGCGCAGGGCCCTGGCGTGATGAATGAGGTGCCTGTCGGCTGGAGGATCGTCCGGCTGGCCGATGTGCTGAGTGAACCGCTGGTCAACGGCCGGTCCCCGCGCCCCGGCGAGGGCGGATTGCCCGTACTGCGTATGCCGGCGCTGCGGGCAGTCACCGTGGACTTCACCCAGTCCAAGAGCAGCGACCGCGTTGACAACGGCCACGCGATACTGCTGGCCGAACACGGGGATGTGCTGGTCGGCCGGGTCAACGGCTCACACTCCCTGGTCGGCGAGGGCGCGCTGGTCGACGGCCCCCCGGCCCCGACGGCCATCCCTGACACCATGATCCGAGTACGGGTACGCCCCGATGTCCTCGATCCGCGCTACCTCGCAAACCTGTGGAAGTCGCCCGTCATGCGGCGCCAGATCGAGGCACGCGCCCGCCAGGGCGCCGCAGCGATCTGGCGGATCAACCAGCGTGATCTGGCCGATGTCCTGCTGCCGCTGCCCCCTGTGGGGGAACAGCGCCGGATTGTCGGCCTGTTGCGGGACCAACTCACCCGCATCGACGCCACCACGATCCGCACCCACAGCGCCCTCGACCAGGCCGACGTCCTTAGCCGCACCCTGACCGCGCGGGCAGTGCGTGGCGGTCTCACCGATACCGCTCGGGTCCCCGCGGACCTGCCCCGGGTTGCCGGTGCAGGGGACGGGGCACTGCCCGACCTGCCTGAACGCTGGCGGTGGACCCGCCTGCACGATGTCGCCGAGGTCACCCGCGGTATCACCCCACCCGGCACGCAGGAGTGGAATCCCGCCGATACGGACGTCTCCTCCCTGCGGGTCGCCAACGTGCAGCGCGGCCACCTCGTCCTAGACGACGTCCGCACGATCCGGCTGCCCCCATCACGGGCCGAGGCAGCCCGACTGCGGGCGGGTGATGTGCTGCTGACCGGCGGCGGATCGATCGACAGCCTGGGCCGCGGCTGGATCTGGGAGGACCAGCTGCCCCACTGCGTCCCCCACAGCCACGTGTTCCGTGCCCGGATCACCACCCATCAGCTCCACCCCGTCCTGCTGGCCTGGCACGCCAACGGCCTCGGCCGCGAGTGGTGCCACCGCAACGCCACCCAGAGCGCGGGGCCAGCATCCATAAGCCTGGCCAGGATCCGGCTCATGCCGGTGCCGGTTGCTCCCGTAGACGAGCAGCACCATCTGGTCGCGGTGGTCCAGGCACACACCGCGGCCCTGAACGCGGCTTGCGCTGCAGCCGAACGCGCTCTCGAGGTGGCCGGACGGCTACGGCGTAACCTCCTGGAACGCGCTTTCACTGGTCATCTGTCCCCTCCGCTCTCCCCGTCCGGGCAACAGGAGTTTGTGCTGTGAACCCCACCGTCTCCTCCCGCCCCGGACACGACCAGGCCCTGGTGGACCGGCTGTGGAACTACGCCAACGTGCTGCGCGACAACGGCACCTCGGGCCTAGAGCTCATCGAGCAGCTCTCCAGCCTGATCGTCCTCAAGCGCGCCAATGAGCAACGCCAACGCCCCCTCAACGGGCGCGACATCCTCGGCTTCGACGCATGGGAGCAGCTCACCTCGACCGAGCGCGACTACCTCATCCCTGCGTACGAGCAGATCCTGAAGCAGCTCGCCGCCCGGCCCGGAACGCTCGGGCTGCTCTTTCGGCGGGCACAAAACCGCATCCCGGACCCTGCCCTCCTACACCGCTTGATCGTCGACGTGGTGGACCGCTACCAGTGGTCCTCAGCCGACATCGGCGCTGTCTTCGAGGCGCTGCTGGCCCGCATGAGCACGGACACGAAGACCGGCGCCGGTCAGTACTTCACACCCCGGCCGCTGATCGAGGCGATCGTGCAGTGCGTGCAACCCGGCATCGACGACACGGTCTCCGACCCGGCCTGCGGCACCGGTGGCTTCCTGATCAAAGCCTTCGACTACCTGGTCGACCACTTTCCTTCAGGTGTCACCGCGGCTCAGCGTAAGCGGCTCGACCAAGGGGCCTTCTTCGGCACCGAACTCGTCGATGCCACCGCGCGGCTGGCCACGACGAACCTCATCCTGCACGGCGTCACCCGGGCCGACGAGATCCACCCGTGCATCACCGTCGGGGACGCGCTGGTCCGCCCACCGGTGCGGCGGGCGACGCTGGTGCTCACCAACCCTCCGTTCGGGCGCCGCTCCACCAGCGAGGAGCCCTACCGGGAGGACTTCTGGACCCTCACCACCAGCCGGCAGCTCAACTTCCTCCAGCACATCCACAGCCTGCTGGAGACCGACGGCCGCGCTGCTGCCGTGGTGCCCGACAGTGTGCTGTTCGAAGGCGGGCCGGGTGAGCTGATCCGGCAGCGCCTGCTGTCCGCGTGCGACGTCCACACCCTGCTGCGGCTTCCCACGGGCGTCTTCTACGCCGGCGGTCTCAAGGCCAGCGTCCTGTTCTTCGACAAGCCCGAACCGCGCCCCGACGGCAGCCCGTCCACGACACGGTTGTGGGTGTACGACCTGCGCTCCCCGCACACGTCGACGGCCAAGTCCATGACACCAGCCGGTCCCGACTACAGCGACTTCGTGTCCGCCTACCGGCCCGGCCGACCCCGCAGCGAACGAGTCGAGACCCCCCTTTTCCGATCCTTCGCCGTCCAGGACCTGCTCGCCCGGCACGGCGTCAACCTGGACCTTCAGGTTGCTGAACCCCCGCCCGGGCCCTTCGCACTGGAAGAGCCCGAGGCCGACCTGCACCGCATGGCCCAGGAGATCACCGCTGCACTGGGCACCGCCCTAGCCGAATTCGCCTCCCTGACTGAAGCACTGCGCCCCTATGGTGTGCACGCGGACGGCCCGGATCGTGAGGCGGAGCGGTGACGGCGACTGGGAACACCTTGACCGGGGGGATGCCGTGCGGCTGCTGCGACTGAGACTTCCCTCCTACCAGGGCCTGCGTCACTTCGAGCTGGACCTCACCGGCGCCCTCGATGGCGGCCATGCCATTGCCACCCTGATCGGCCCCAACGGCGGCGGCAAGTCCCGGGCCCTGCACGCGCTCGCCGAGATCTTCGGCGCCCTACACCGGCCAGGCCGCCGTGCGGCCTTCGCCTTCGAACTCGACTACGAGGTCCACGACAGGACGGTCCGGGTCGTTCAAACCTCCCCCGACACCTCACCCGAGCTAACCGTGGACACCTCCCTGGGCCGACCGATACGCGCGGCCCGCGAAGTGTGGGCGCAGCATCTGCCCGATCACGTCTTCGGCTACCAGGCGCACGCCCAGGCTCCCTGGAGCAGCGAGTTCGACCAGCACCGCCTCTTCGCCGCCCGCCTCGTCGGCCAATGGCGCCGACAGTGGATGACGGACTTCGACCAGTGGCGCGCACACCACGCCCCGAACGAAGGCGAGCTGTGGACAGAGCAGCTCACCCTGCCCATCAACTGCCCCCTGTACACGCCGGTGTTCCTGTGTACGCCCGCGCACCTGCCGCTGCTGCTCCTCGCGCAGACCACCCACTGGTCCGACTCGTTCGGCACCTATCTGCGCCGCCACTCCTACCTCCAGCGTGTGACCTCTGCGGTCCTGCGGATCCGCGCGCCACGCGCCGCACGCGCCCCGCACCTGGCCGCCCTCCCGTACTGGGGCCTGGGCGGGCCCGCCCGCACCCTGTTCGCGGCCGCCGCCGAATCGGGGCGGTTCGGTCTAATCCCCGATGCCGACCCGGTGGACGGAGCCGGCAGCCCCGCCGACGGGTTCCAGATCGTCCTGGGCACCGCAGAAGATGTTCGCGCCTTCCGTAACCTCTTCGACAGCGATCTGTCGATGTTCGGCCTGCTCGCCACCTTGCTGGATGCCGGCTACCTCACCGTCGACGTCCGCCTGGAAAAACCCGGCGCGCTCACCGTCGGCCTGAACGACCTGAGCTCGGGGGAGCAGCAACTCCTGACCATTTTGGGCCTGCTGAGGCTCCAGCGGGCACATGAGTCGCTGTTCCTGCTGGACGAACCCGACTCCCACTTCCACCCCGAGTGGAGTCGGCGCTGGTACTCCTCCGTACGCAGCGTGCTGGGACCGCATCAGCACTCGCAGTTCCTCACCGCCACCCACGAACCGCTCCTGGTGTCCAACATGACCCGCGAGCAGATCCGCGTCGTCACCACCGACGAGGAGGGCTGGGCCACCGCAGTGCTGCCCCGGGCCAACCCGCGGGGACAAGGCGCCGGCGGTCTGCTGACCACCGACCTGTTCGGCCTGCCCACCCAACTGGATGAACACACCCAGGAACTGATCGACCGCCAGTACGCGCTGCTCCCTGAGGCGGACGGCGACCCGGTCAAACAGGCTGCATTGCGCGACGTTACCGCCCAGCTCGACGCCATGGACTTTCCCACCTCCGACCGCGATCCGCTCGTGGCGGCCCTCCTCGCCGAGCTCCACCGCAGACGCCTCGCACTCCTCGAGGCCGCGCAGGGACCCAACCCGCCCTCGCCCGAACAACTGCAGACCCTGGTCGCCGAACTGTTCCACGAGCGTTTCTCGTCGGTGATCTGACGCCGATGAGACACGTCAACATGAAAGGGCTCACCGCCCCGCCGGCCTGGACGGCCAAGGCTAAAGGCACCCTGGACGCGGTCAGGGCCGCGATGGCCGCCAACTCCGAGCGCGTTTTCACCGCGCACTGGACCGAGGACGCCGTACGCGACCTGCTCCTCGAACTTGTCGGCGTCAAGTGCTGGTACTGCGAGACCCTCATCGTGCGCGCGGACGTCAACGTCGACCACTTCCGGCCGAAGTCCGAGGTCCTCGACGTGCCCGGCCACCCGGGCTACTGGTGGCTGGCCTACGACGTGTCGAACTACCGCATCGCCTGCAAGCACTGCAACAGCGGCGGAGCCCGGTACAACGGTGTCCCGGAAGGCCGCGCCAAGGGCAGCCAGTTCCCGCTCCTGGCCGGACCCCGCGCCCGCACATCACTCGACGACCTGGAACGCGAACAGCCGCTGCTCCTCGACCCGGCCCACCACGGCGACCCTGACCTACTCGGCTTCGACACCGCCGGCTACGCCCGACGTAGCAACACCCCCTACTCTTCGGCCGAAGCAGACAGCGGCCTGTGCCGCGCCGACGAAACCATACGGATCCTGGCACTCAACGACTCCCGGATCGTCCCGCTCCGCAGCCGCCTCATGCAGGAGGTCGGCGTACTCGCTCGCTTCGGGGACGCACCCGAAATTCAGGCGTTGATCGACGCGAAGGTAGAGCCCCAAGCTCAATGGAGCGCGGCAGCTGCCACCGCCCTGGCCCTGCAGCGCGCCTGCAATCGGCCCATCGCCGCGCCTGCCCAGCCCGCAACGACGCCCGTCGTTACACCGGTCCTCGATCCGAGGCGTTCGAGGGTCGACCTGCGAGACCTCCTGGAATATCTAGATCCGGACGACCTGAAGGCCGGGATCACGCTGACTGGCCGGTACAACAGGACGGTGTACCAGGCGACCCTGAAAAGCGACGGTGAACTCGATGTCTTGGGCCGTCTGTGGCGTACTCCGACCACCGCAGCCAGGGTTGCGACGGGCAGCCGCCAGATCGACGGTTGGGATTTCTGGCGGCTGACCATCGCCGGGGTGGAGCAGACCCTCGCCGAGTTCCGCGCCAAGCACTTCCCGCCTGCCACTCGACCCTGAAACGGCTGAGGTAGGGCCTCCGGTCCGGACGGAGTGAACCGTTCCGGGTTCGGTAGAGGCTCGATTTCGTGTAAGGATTCGAGTCATGGCACGTCCCTCGTCCTACCCGCCTGAGCTGCGCCGTCGTGCGGTGCGCATGGTCGCCGAGGTCCTTGGCGACTACCCGAACGAGTCGGCCGCACTGCGGGCCGTCGCGGAGAAACTCGGCATCGGCTCCGCCGAGACGTTGCGCAACTGGGTTCGGCGCGACCAGGTCGACTCCGGGCAGCGCCCCGGCACGACCACGGAGGAGTCCGCGCAGATCAAGGCGATGAAGAAGGAGATCGCCGAACTCAAGCGCGCCAACGACATCCTGAAGGCCGCGGCGGTGAACTCAACCGGTCAGCGCAACACCCGAGGTGGTGAAGGGTGTGGTGTATGGCGAGAATGGGTCGTCCGGGCATGTCGGACGCGCAGAAGCGGGAGTTGTGGGACCGCTGGAAGGCCGGCGAGTCGATCAGTGAGATCTCCCGTGCCCTCGGCAGGCCACCGGGGTCAATCTTCACGATCGTCAAGGCCAACGGCGGATACGTTCCACCTGTCCGACGCCGTCGGCCTGGCTCGCTGACCTTCGCCGAACGGGAGTCGATCTCCCGTGGTCTGGCCCGGGGCGACTCGATCCGCAAGATAGCCCGCACCCTGGAACGTGCCGTCTCGACCGTCAGCAGGGAGGTCGCCCGCAACAAGGGAGCCAAGCACTACCGGGCTGTGGATGCGGAGGACCGCGCCTGGGATCGCACCCGACGCCCCAAGCCATGCCTCCTTGCCACCAATGAGCCCCTGCGCGCACTGGTCGCCGAGAAACTGACCGAGGACTGGTCGTCCCAGCAGATAGCCGGCCACCTGGCCAAGACCCAGGCGGTCGGCACGGGCATACGGATCAGCCACGAGACGATCTACAAATCGTTGTTCATCCAGGCCCGGGGAGTGTTGGCCAAGGCCCTGCAGAAGCACCTCAGATCGGGACGACCGACCCGACGCAATATCCACAACACCGTTACTGGTCAATGGCGTTCACAGATCAAGGACACGATCCCCATCCACGAACGCCCCGCCGAGGCGGACGACCGCGCAGTGCCCGGACATTGGGAAGGAGATCTCATCATGGGCAGCGGCGTCACCCAGGTCGCGACCCTCGTCGAGCGCACCACCCGCTTCACCATGCTGGTCCAGCTCGACGCACGCGACACAGCCACCGTCACGGCCAGAGTCTCGACTCAGATGCTCCAACTTCCCGACCAGCTTAGGAAGTCACTGACCTGGGACCGCGGAATGGAGCTGGCCGCCCACAAGAGCGTCACCGCCGCGACCGGCATGGCCGTCTACTTCGCCGACCCCCAGAGCCCATGGCAGCGCGGCACCAATGAGAACACCAACCGCCTCCTGCGCCAGTACCTACCCAAGCGCACTGGACTGGGTCACCTCACCCAAGCCGACCTGGACACCATCGCCCGGCGGTTGAATACGCGCCCCCGGCAGACCCTCGACTTCGACACCCCAGCCGATAGGCTGGAGGCCCTGTTGCGCTGACCGATTGAGTCCACCGCGAGTTTCTTCGCGGCCGAGCTCGACCGGCCACATCTTCGCTCGTAGCGTTCGTCGACGAGCACCGGGACCGCTTCGGCGGCGTCGAGCCGATCTGCCGAGTGCTCACCGAGCACGGCTGCAGCATCGCCCCCTCCACCTACTACACCTTCAACAACCGCACCCCTCGGCCCGTTCGGTCCGCGACACGGAGCTGAAGGAACTGATCACCGCAGCCTACGAGGACAACTTCCGGGTCTACGGGGCCCGCAAGATCTGGCGCGAGCTGAACCGCCGCGGCCACGCGGTGGCCCGCTGCACCATCGAGCGGCTGATGCGCGACCTGGGCATCACCGGAGCCGTCCGCGGCAAGCGCGTGGTCACCACAGTCCCCGACCCGTCCGCCGAACGGGCCCCCGACCTGGTCGACCGCGACTTCGTCGCGTCGGCACCGAACCGGTGCTGGGTCGCGGACTTCACACACGTGGCAGCATTCGCCGGCGTCGTCTACGTCGCGTTCGTCGTGGACACCTTCTCCCGCCGCATCGTCGGCTGGTCCGCCGCGACCACGAAGCAGACCAGGATCGTCCTGGACGCCCTGGAGATGGCCTTGTGGCAGCGTGACCGCGACGGATACCCGCCCAGACGGGGAGAGTTGATACATCACAGCGACGCAGGCAGTCAGCACACGTCTTTCCGCCTGGCCGAGCACCTCGACGCCGCCGGCATCGCCGCCTCCATCGGATCCGTCGGCGACGCCCACGACAACGCCCTCGTGGAGAGCACGATCGGGCTGTTCAAGACCGAGCTGATCAAACCCCGGCGGCCCTGGCCGACCCTCTCGCAAGTCGAGCTCGCCACCGCCGAGTGGGTCGATTGGTACAACCACCGCCGACTCCACGGTGAGATAGGCCACGTCCCACCCACCGAATACGAGACCACCTACCACCTCACAACCGCAAAACCACAGGTCACAACCACAAGCTGAGGTCTCTATCCAACCCGGTGCGGTTCACTTTGCCGACTCGGAATGGGGCGGCACGTACGGTGGGTCATGACGGTCTCCGATCAAGGGACGAGTCCGCCGCCCCTGCACCGCTGTTCTTGGCCGGACACGGTGCAGGGCACGGCTGGTGATGACCACCACCCTCCCGGCTGAGAGCTGCCGAGTGCAGCTCACCAGCCCCGGATCTGGATGTAAGTTCGGTGCCATGGACGAGGACCGGACCGCCACCTGGGCTGAAGGCACGTCGGCCGATTTGGTCGCCGACGCGCATGCCCTCGGGGTGAGCTCGGTCAGCACCCGTATGGTGACCGCCTGGGTGGAGGAGGGGCTGCTCGCCAGCCCCGAGCCGCGCAAGACCACCGCGCACGGTAGCGACCCGCGCGTCTTCCCGCCCGAGCAGCGCGAGCTGTTCACCAAGCTGCTAGAGGCTCGGGAACGGTCCCCGCTGGGGCGCGTTCCCCAGCGCTCGATCGTCCGCGTTGTGCTGTACCTGTGGCTGATCGACGACAGCGTGGTGCTCACCCCGCAGGCGCGCCGTGCTTGGCGCACTCACGCTCGGGCCACTGGTAAGCAGACCGCCGCCAGGCGCAGCGAAACCGCCCGTGCGATCGTCGCGTCGCTCGCTCATCCGTCAGCGACCATCCCACAGCGGCGCGCAGCCCAGCTCGTAATCGAGGAGGGCGAGCGGACGGGCCGGATCGACCTGCCGCGGCTGACATCCGTTCTGACCGAGCTGTGCTCGCCGTGGCCGGCCCAGCCGGGCGCACCGCGAATCGAGCGTGCCATCCCGGGACCGTTCGGACCGGTCACGGTCCAGCACCACATCGCCATGTGGTACGCCAGGCACCAGGCGGTCCGGCAGCTCCGCAACGAGGAAGTCAACGAGGCTGCCTTGATCGGGTGCGCGCCATCCACCGCCCCGAATGGGCCGACTACCAAGCCCGTCGGTCGGCTCTGGCTGCCCAGGCCGGAGCGTTCCCCACGGCTTTCGCCGAGCCCGAGACTCTGGAGGGCCGCGCGATCGAGGCGGTCGACGCCTTCGTAGGCACGCTGGCCGGCGAGCTCGGGCTCATCGAGGCCGCGTTCAACACCGCCGAGACGCTCCGCAACAGGGCGCGTTGGCCGTGATACCAGGACGCCAGCCGCACAGAGAGTCGCTCACTCCTGGTTGACTTCAGAAGGCTCCTCCGTGGCCTCGGAGTCGTCCTCATCCGAGCGTCGCGCTGCGGCCTGGCCGGTGACGAACACGGTGACAATGGCAGCAATGTCTAGCGCTGCCACGACTGCCGCCAGTCCGCCTTCGCCCAGATATGCCAGGTAGGCGGCCAGTGCTCCCAGGAGGAGTACTGCGGCGAGACCACAACCCTGACCGATCCTCGCAAGCCGGAACGGCTGCGTGACGATGCGCTCTTCCATGTCATGTCGATGACGCTGCTCGCGCTCCGCCATGCTGAGGATTCGGTTGGCGGCGCCGGGATGCACCTGCTCGTAGCTCTGGAGCTCCCTTGCATCAGGTAACGGGCCGGAACGGCTCACCGTGACTTGGCGGATCTCATGAAGCTCAGTCTTCATCCCCTGGAGGATCGCCTCGATGATCAAGGCATGTTCCTCTGTGGGTTTAGCCCCGTCACGTTTCAAGCTCACTGGCATTTGCTGCGCTGGAGGCTTGTCTACTTCGCGGCTTTGCTCCGGTCGGTCTCTTCCAAGGCCATCGCCGTGCGAAGGTCCCTGGCCACTGCCTGCCAATCCGACCCCCGGTAAACCCGGGCAGGACTCGGCTGGGCCCTGCGCATGGCTCGATAGGTCCCAAGCCCCGCAACGTCGATAGTCGAGCTGAGGCCCACGACCGTAGGCGAGAGAGCCCGTTTGCGCGGCGATCTCATCGTCGTCTCCTTGTTGGTGGTGCGGCCCACCACCGTAACCTCTGCGGTGTTTGACCGGAATAAGTCCGGTATTCCCGTCCTCTGATCGTATAGCCCTGATACGAGGGCAGCCTGTCGGTCAGGACTCCTCGCCCTATCCACCGTTGCCGTGCCGGAACCGGGACCGAGTCCTCTTGGAGCTTGGCGATCTTACGGATCGACTCAGCCGCAACGTCCTCGGCGAGCACGGTTGGCGACCGCTCAAGATCCTCGGGCCTGGTGCTCGGCTCAGCGCAAGTGGGGGCCCGGCTGGTCTTGCTGCACCTGCTGCGGGCGCAGTTGAAGCGGCTGTCGCTGCTCGGCTGGGCGCTGGGCCGAAGCCTGGACTTGCCGCTGATCGGCGGGCTCGACACGACGGTTCGACGCGCGCCGGGCGGTCCGCGTTGGCTGGCCACTCCCCTGCTGGAGCTGGTCGCGGTGGGCTTGGCGCTCGGCCTGGCGGCCGGCGCGGCGGCGTTCGGCGAGGGTCGGCTGGTGGTGTTCCTCGGTCTGCCGCTGCTCGGGCCGGGCGGCCTCGGCCGTCAGTTGGCCGCGCTCGGCGAGCACCGCGCCGACGGTCTCGGCGACGTGCTGCTGGGCCAGGGCTGCGTCGTCCAGGCGGGGGCGGCCGGTGAGCCAGGTGGCGCCAGTGCGGGCGGCGACGGTGCGCAGGATCTCGGTCTGGTCGGCGTCGGGCAGGGTGCGGTAGACGTCGGCGGCGAGTCGGCGCAGGGCCTGCTGGTCGCTGTCCGCGGTGGCGGGCGCCGGGGTGTTCGGGGTGGTGGCGATGCGGCGGGCGGTGATGGCGGCTTCGGTGGCCGTCCAGTAGGTGTGGTGGCCGGTGCGGCCTTCCTCGATGTAGGGGCCGGCGGGCTGGGCGGCGGTGTCGTCGGTGACGCGGTACTGGTCGCGGTAGGCGGCGACGAAGGCGAGCTGCTGCTGCCAGCGGGCGCGCTGGGTGGGGTCGGTGGGGGCTTCGCCGAGGGTGCGGCTCCACTCCGGGCGCATCTCCGCGGTGCGGTCGCCAAGGGCCGAGACGCGACCCGCGATCAGGGCGGTGCTCTCGGTGAGGTAGTCGTGGTGGCGCTCGTTGGCCGCGGTGGAGTGCGGCACGCCGCTGATCCAGGCGGGGAGGTCGGCGCGGCCGGAGGCGGCGCGGGTGTGGGCGAGGGCTTGCTGCTGGGCGTGCTGGAGGAGTTCGGGCAGCGCGGTGCGGCCGGTCGCCCCGGTGAGGGCGGTCTCGGCGGGGGTGCCGGTGTTCTCGATGGTCTTGAGGGTCCAGGCGAGGGTGCGCCACAGCTCCGCCTCGGCGCCATCGCCCTGCTGGGCGGCGGCGGCCGGGGCGTCGGCGGCGAGGTGGCGGCCGATGCGCCAGGCCAGGACCTGGCTGAGGCTGTCGGTGCCGGTAAGCGGGTACTGCTCGGCGACCTGCCGCAGCAGGGTGGCGGGTTCGTGGCCGGCGGTCTCGGCGCGGCGAAGGGCGGCGGTGAGGGCGGGCCAGGTGCTCTCGCCCAGCGCGCGGGTGGCGTGCTGGGCGCCGAGGACGTCGGCGGTGAGGGCCTGGTGGCGGAGGGTTTCGGGGGTCTGCTGGTGGTGTTCGGGGATGCCGTCGGTGGCCAGGGTGGTGCGGGCGGCGCGGGTCAGGGCGGTGACCGGGTCGCTCGCGCCGGTGGTCTGGGTGGCGGCGGTAGTGAGCAGGGTGGTGGTGTCGCGGCCGGTGCACTCGGCGGCGGCCAGGGCACCGGCGAGGTGGGGCCACTGCGGGTGGGCGGTGACCGTGTCGGTGGTGGTGTTGAGCGCGGTGGCGGCGGTGGCGTAGCGGGTCAGGGTGTCGGCGGGAACGTGCGGGTGCGCGTCGGGGGCCTGGGCGGCGGCGGGCGCGATGTGCAGGGCGACCGGCTGTTCGGTGGCGGTCTCGGGGTCGAGGCGGTGGGCGGGCAGGCCGGTGAGCTGCGCGACGAGGGTGGCGTAGCGGGTGGTGTCGGCGGTGGTGGGGGCGTTGAGGTGGGCGGGGGCGGGGCGGTCGTCGGTGATGGTGTTCAGGCGCCAGGCGAGGGCCTGGGCCGGGGAGTCGGCGGGGTTGAGGTCGCCGCGCCAGGTGGCGGCGGCGAGCAGTCGCTCGGGCTGCCAGCCGACCGTTTCGGCGGCGCGCAGGGCGCGGGTGACGGCGGTCATCGCGTCGTCGGTGGTGATCTGCTCGGCGAGGGCGGGGCCGAACAGGCGGTGGATCAGCTGGTGGTAGTAGGGGGTGGTCAGGGTTTCGACGGCGTGCTGGTGGCGGGGCGCGAGGGTGGCCAGGGAGGCGGCGTCCTCCTGGGCGCCGCGGATGGTCTCGGTGGCGGAGAGCTGGGCGCCTTCGCGGGCAAGGACGCGCTCCAGCACCTCGCGGGCGGCGAAGGAGTCGGGGTCGTTCTTGGGCTTGTCGAGCTGCTCGTCGGTGTCGAACGGCAGCAGCTCGTGGGTGGCGGTGTAGAGGGTGGTGGTGTGGCGGGCGCGGGTGAGCTGGACGTACAGCTCCTCGCGGGTGGTGTCGTCGGTGACCAGGGGGTGGGCGGTGTCGACGGTGCCGCCCTGGGAGCGGGTGATGGTGGAGGCGTAGAGCAGCTGGACGTGGGCGGCGACGTACTCGGCGGGCAGGGTGAGGCGTCCGCGGTGCTCCAGGTGGCGGACCTTGAGCGAGCCGTCGTCGTAGCGCTTGAGGACCTGCCAGGCGTCGCCGTTCTTGACGAAGTCCGCGCCCCGGTTGGTGGTGATCTTGCGGTTGTTGTCGCGGGTGACGATCCAGTCGCCGCGGCCCGCGCGGTTGCCGTCGCGCAGCAGCACGCCGTCGGTCTCGACCTGGCCGGCGGCCACACGCTCGTCGCGGGCCCGGGCGGACAGGGCGGTGACGTCGGTGCCGGTGCGGGCGCTGATCAGGGTGGTGCGGCCGGCGAGCATGTCGGCCTTCCAGCCCTCGTACGCGGCCTCGACCATGGCGGTGCGCGAGCCGCCGACCACCCGCTGGTTGGCGAAGTAGAAGTCCAGACCGGAGCTGTTGCCGGTGCGGATCTTGAGGGTGGCGGCGGCCTCGTCCTTGTTGCTGAACCGGTGGAGCGTGGTGAGTTCGACTGCGCCGGCTTCGGCGGCGATCAGCCGCAGCGCGCCGCCCGCCTCGACGGAGCCGAGCTGGCGGTAGTCGCCGAGCAGGCGCACGCTCGCGCCGCGCTCGGCGGCGATGCGGGTGAGGCGGTCCAGGTTGAAGGTGCCGGCCATACCGGCCTCGTCCACCAGGACCACGTCGCCCGGGTTCAGCACGAAGCCGGCCCGGTTCGACGGCACGTTCTGGCCGCTGCCGAGCTGGGCGGCGTAGGTGCCGCCGGTGTGCTCCCAGAGGAACTTGTGGAGGTTCTCGGCGGGCTGCTTGAGGTCCTTGGCGAGGACGGCCGCGGAGGCCGCGGAGGTGGCGAGCGGGACGACGCGCTGGCCGGCCTGGTTGGCGACCTGGACGTACGCCTGCATCGCGGTGGTCTTGCCCGAGCTGGCCGGGCCGAGGCCGAGGGAGACCAGCCGGGTGTCGGTGGCGAACGCGGTGACGAGGACGCGCTGGCCCTCGTCCAGGGCGCGGTGGCGGGCCTCGAAGCCGTCGATCGCGGCGCCGACGAAGGCCGGGTTCAGGCCCTCGTTGACGGGGGTGAGGGCGGCGGCGACCAGGCGGCGCTCGGCGTCCAGGATGGCGGTGCTGGTGTAGCGGTCGGAGGCGTGCTGGACGAACACGGAGTCGCCGTTGGCGCGGCGCAGTTCCTCGGGCTCGTCAAGCAGGGCGGGGGCGTCGACACGGACGCTGTGGGCCGGTGAGACGGCCTCGGTGACGATCGCCTCGACCAGTTGCCGGTGCTCGGTGGTGCTGGTGGTGGAGTGCTCCGAGCGGGCCAGGCGCTCGGCGTGAGCGCGCAGGTTCCACACCGTCCACACCGCGCGCTCCTCACCGACGGCGGTGATCACGGCGGCGGCCAGGGTGGGGATCTCGACCGGCTTCGGCTCCTCCTGCCGGGCAGTGGCCGGGATGCTTTCGGGCGCGGGGACGGCCGCCATCACGCGCTGGACGACGTCCTGGCCGTGAGCGGTGGTGACGGTGCTGGTCCAGTCGGCGCGCATCTCCTCCAGGGAGCGGGCGGCCTTCTTGCCCTCGCGGGTGTCGAGGTTGGCCTGGCGGGCGAGCTGGTGGGTCATGCCGCGGGAGGGGTCGTGCCCGTGGTCGCGCCGGTACTCCCGAAGCAGCTGCTCGTAGCGGGCCTCGATCTCGGTCCGGCGGGAGGAGAAGTGGGTGATCGCCTCCAGCGGGACGCCGACGATCTCGCGCACCGGCTGGCGCTTGGCCACCGCGTCCTCGCGAGCCTCGAAGGTCACACCGAGCCGGGCGGTCAGCTCGGTCTCGAACCGCGAGTTGTAGAACTCGGAGGTCGCCACGGTCATCGCCAGCAGGCCCCGGGCGTCCAGCGAACGCCACTTCCCGTCGACGCCCTGGATCTTGTTGGCGACGACGACGTGGGTGTGCAGGTTGGGGTCGCCGGCCCGGCTGTCGTAGTGGTCGAACGCCACGGCGACCAGGCCCTTGGTGTCGATCTGGGCCTGACCAGTGCTGCCGGTGCGGGTGTGCGCGGCATGCTCCTCCAACAGCTCCAGCGCGGCGTCGCGGGCGGCCTCGTGGGCCTCGCGGACAGCGGCGCGGACCCCCGGGCGCTCGTCCAGCGCCCACAGCACCGCAGCCGACTTCACCGGGGCGAAGACCAGGTCGAAGCCCGCGACGGCGGCGCGCTGACGGCGAGACTCCTCCTGCTGGACCTTCTTGACCTCGGCGCTGGTGGGGGTGCGCCGGGTCTCCTTCCGGATGACGGCCAGGCGCCGCTGAACACGCTTGGCGAACGGATCGAGAGGCTCGTACTCGGGGTACTTGCGGCCGAGGGTGGCGGCCTTGATCGCGGCGGCCTGGACCGCCTTGAGCTGGTCCCCGTCCATGTCGGCACGCACGCCTGCGGCCAGGTGCTCGGCGATGATCCGTTCGGCGTCCGGGTGCTGCCCCAGGCCGAACAGGTGCTTCATCTGCTGCTCGGTGACGCTGGTCCCGTCGAGTCCAAGCAGGGGCGCGCCGCGGCCGAGCCAGACGCCGGCCGGGTTGCCCTTCTGGGTGTAGTACTCCTCGGCGGACTGACCCCGCTGACGCTGTACATCGCCGCCCGCGACCTGGCGCGTCAGGTAGGTGTAGCCGTTGCCGGCGGTGAGCTTGTGGATGGTCATCAACGCGACCACCCCCAGCTTTCCGAAACCCGGGCGAGGGTAGGCGCGGCAGCTATTCGAGCCGCCGTTCCACCTGCCTCACCAATTGCCATACGGGTACTTTAGCCCCGCACAGCGGACCATGCTCAGAATATCTGCAAGAGGTGTCTGGATGGCTTACGAGCGAAGCAGAAGGTGATGCCAGGCGGTCTCGACTCATTGCTCCTGAACTGCAGAGTTGATGAATCGAGACCGCGAGGTGACGATTTTCCCGTCATTTATCTATCAATATTTATCGTCGCTTCTTAGGGCTTCTCAGCCGCCAAAACAAGGGGTTTCCGAGCTGGGCTTTTGTAGTTAGAGTCACGATCAGAAAGGGCCACTCGCTCCTTCTGATCCGATTTGCCTCCGGCCACTGCGGAGCAACGGATCCGATCCCCATCGACTCCCTGGGATGCCGCCCCTGTGACGAACCGTGAACCTCGTACTGCTCACGCCGACGCGCCGCTCGCGCAACTGCTCCGCTCGCGCCCCGGATATGTGCCGCCGACGGTCGGCGAGCGGGTGGTTGTCGTCGCAGACCTGCTGGCACCCAGCCGCCATCCGCGCGCCGTGATGAACCTGCTCCGGTTCGTTGGCGACTGGCAGCCGGACCGTGTAGTTGTCATGAGCGCCCGCCAACACGGTTCGACTCACAAGGGCTCCGAATGCGCCACGAGCACCCTCGGTCGCCTGCGCGCTATCTACTCAGGAGACATCGTCATCCAAGCCGGGGTTGGGGCTGGCAGAGACGCCCTGACTGTCGGCTCGTGTTCGTGCTGGCACCCGGTCATCTCTGATCTAGGTCTTGCGGTCACCGCCGGAATCCAACCGGTCGCACCGGGGTGGCTGAGCCTCAGCGCGACCGGCCCCGGTGCCAGCCGCTATCCGGGCGCGCTCGCCATCCTGCTCGCTCGCGGGTTCGGACACTCCATCATCTGCAGCGGAACCAGCGGCCTCGCACTGATCGGAGAGATCCCGACCGACGACCCGACGGCCGACACTCTCTGGGGCTTCGAGATCGGAACGCTTCGCCGCACTGCACCGTCGACAGCCTCGTCATTCCGTCCGGCAATGGGCTTCGGAGTGGTCGACTCAACGACCGGCATCGCCGAGCCCACCGCCGTCGCAATCTCGCGCAGTGGGGCATTCACGTTCGACGGGGTCACCTACGCCGCATAGCGGCTTTCCCGCACAGCGGCGAGCGGGGCACGGCAGCATGCGACGTACGCTCGCAGGCCGTCGGTACCAGCTCAACAGTTCCCTGTGGCGGCGTCTGACTACATGGCTGCATCTAGATACACCTGCACCGGCTCGAACAGACCGTACGGAACGAACTCGGGGATCTGCTCGCGGGTGATCCACGCCAGCGCACCCAGCTCCTCGGTGTCGACCACCGTGGCCGTGCCGCTCACCACCTCGCAGGCGGTGTACGACATCTGCCGACCGGTCTTCGGGTGAACGCGCTCGCCGAGCGGGTGGACGGCCTTGACCATCAGGCCGACCTCCTCGGCGGTCTCGCGGACAGCAGCTGCTTCCGGCGATTCGCCGACCTCGACCTCACCGGCCGGGAACTGCCACGACAGCTCACCCTCCTTGACCCGCCGCTGGACCATCAGGACGCGGCCGTCCTGGACCACGATGGCAGCGGCGATACCCGGCTTGGTGCTGGTCGGCTCAGTCATTCTGGGACTCCTCCAGGGCAGCCAGGATGGGCGGGAAGATCGTATCGACGGGGATGAACCGGGGCACCGCGTTTCGCGGAACCCACATCACGTCGGCGTTCTCGATCTTGTCCTGGTTCTGAGCCTCGCCCACCAGGTACTCGGCGAGGAAGTACTCGCACCACACACCGGTGGACGGGTGGAGCCGGCCGCCGAGGTCTTGGCGCACGGCGCAGTGGACGCCGGTCTCGGCCAGCGTCTCGCGGACGGCAGCTGAGGCTGGACTGCCACCCGGCTTGATCACCCCGGCTGGGAACTGCCAGCGGATGCCGGCGGACTCGTCGTCCCGGCGGCAGACGAGCAGCACGTCCGTACCGCGGACCACCACCGCGACGGCCACCCGCAAGGCTTGGGCGGCCTGGCTGCCGGTGGACTCGGTGAGCAGCAGCGCAAACCGCTTCTGCGCGGCGGGCGCCGCTGCTTCCAGTGCTTGGTCGAGGAGCTGGTGCATCTCGGTGCGCGGGACGAGTTCCGGGCTCTTGTGCCAGCTGGCCACCGTGCGGACCGCGATGCCGAGCCGGGCGGCGAACGCCTCGTTGGTGTCGCGCAGCGCCTCCTGGAGCCAGCAGGCGGATCTGCCTGTCCAGCTGACCACCACGTCCACCTGCTGCCCCTCCCCGAGCTTCGAGCTGACTGGTTGGCTACGCCTTGCTCTTGGCTTCGAGCACCGGGCGCAGCAGCCGCAGCGGGGTAATCCAGTCGTACTGGTCACGGCCACCGCCGGCCTTCGGCTTGTGCGGCACGTAGTCGCCGAACAGCACGCCCATGGCCTTCAGCCGCTCGACGTTGGCCGCGTAGGCCGGGTGGGCGGCCTGGGCAGAGTTGACGTACGGCTGGGCGACCACGGGGATACCCAGGCCATACGACTCGGTGAGTATGCCGAGCAGCAGGGTGTCCGCGTGGCCGTCGGCCCACTTGTTGATCGTGTTGAAGGTGGCGGGCGCGACGGCGATGGCGTCGGCCGGCGGCAGTGAGGCCGGTACGTCAGGCGTGCGCCAGGCCGAGCGGATCGGGTAGCCGGTCTGCTGCTCGATGGCGGCCTGGTCGATGAACCCCATGGCGTTCGGGGTGGCCACCACGCCGACTCGCCACCCTTCCTCTTGAGCCGCGGTGATCAGCTGGCTCACGTCGTCGGCGATGCCGGAGGCGCAGACGGCGACGTACAGAAAGGGCTGGTTGCTCAAGGTCGGACTCCCAACTCGCGGCTGAACTGACGTAGCTCCGGCAAGGCACCGCGACGGTCGCGTGCCGTCATGTCGGCCACCAGCTCCCGGATGTCCGGGCGACGCCTGATGTCCTCAGCAGCGTGCCGTTCGGCGATGCGCAAGGCGCGGTAGCCCTCGGACAGTTTGCCCTGCTGGTTGAACGCCCTGGCAAGGTCCACCCACAAGGCGGCTTGTCGTTCCGGGGCTGGGATGCGACGGCGCAGTAGTGGCCTGGCCGCCTCGACGGCGGCACCGGCGTCGCCCAAGGCCACCGCGGCCGACACCCGATGCAGCGCCACGTTGGTTGGACTGAAGTTCGCCCAGGCGTCCGGGTGATCGCGGTCGACGTACCGGGCCACTTCGTCTGCCTGGTCCAGCAGCTCCGTGGTGGTGGAGCGGTCGCCGCCGGTGCTTGCAGCGGTCACCCCACGCAGCAGCATCAGGCCGAACGCGGCGAGGTCTCCGGGTTCGCGCTGGTCGTAGTGGCTGCCGAGCTGGTCGGCGGTGTGCTGGACCATCGTGACGGCCGGTGCGGTGTGGCGTTCGCGGGCCATCAGGTGGGTCTGGACCCGGACACTGGAGGCCAGGACTATCGGGTTGCCGCTGCGCTCGGCCTCGCTCATCGCCCGCCCCACCGCGAGCCAGGCGTTGCCGGTGTCGCCGAGCTTGATCAACATGCTGACGGTGGTCTGGTAGGCGGTGGCGGCCATGCTGGCCAGCATCAGGCTGTCGGGCGCGTCGTGCTGAGCACGGCGAAGGGCGGTGAGCAGTGCGGGCAGCAGGGCTTCGAGTTCGGTGTAGCGGCAGCCGTAGAGCAGCCGGCGAGCCTTCGACAGCTCCTGACGAAGAGTGGCCTCGGCGAGCAGCTGCCGGTCGGCGAGGCCACTCGCCGTGGGCAGGAGGGCTTGGACCAGCTCCAGGCTGGCGGTGTGAGGGCGGGCAGCTGGGACCGCGAGAGCTACCACGCTGGCTGCCAGGAAGCCTCGACGCTGCATGTCGTCGGTCCTGAGATCCGTGCTGCTGGGGGAGGCGGTCAGGCCCAGGCTTTCCAAGGGAATATCGAGTTCCGCCGCGACGGCTCGCAAGATCCGTACGTCGTCGGTGCCGGCGCCCTTCTCCAGCCGACTCAGCTTCGACTGGTGGTAGCCCAGCTTGGAAGCCACATCGTGTTGCGACCGGGCAGCGATCACCCGGGCGCGACGGATCACCGATCCGATCTGGCGTGCGTCGATGGCCGCGGGGACCGCCTCCGACATGACTCCTCCTGCCACCCTCAGCCTGCCTGGCGAAGGCCGCGCCGGCCGATCTGGATCAAGATGCTATGCACGATCTGCATAGCTCATGCAGAACATGCGACAAGGCGGACCAGCCTGCTACCTCGTGGAGTTGACTTGGCCTCAGCCACGCCAGCCCTGAGAGGAGCAGCTCATGCCACCGAACCGTCGCCCGCCGCCCGCCGGTCGGCTTGCTGCACCGCGAGTGCACCGTCGCCGCACTGTGACGGCATGGTGCGAAGTGGGTGGCAGTTCCAGACTTAGGGCCGAAGCAAGACCCGCACCTGCACGGACAGTTGCAAGGCCAGTACTGGCTGAAGTCTAGGTCAGCACCGGTCTTCATAGTGAGTGATCAGCAGGAACGCTGTTCGACTCCTCTGCGGGTCTGCCCGGCGTACCGAAAACCGCTTCACTCTCGCAGGTAATCTCGGTGCCAGACGTGTTTGATGCACCGTCAAATCGCCACTCTGGCAAGGGAAAGGGAACAAATGACCGAGGAGACCCAGGGCCAGGTCGAGCGCACGCTTGTCCTGCTCAAGCCCGACGCGGTGGCCCGTGGTCTGTCCGGCCGGGTTCTGCAGCGGTTCGAGGACGCCGCGCTCAAGATCGTCGGCACGAAGATGAAGTGGATGGACGCCGAGTTCACCCGCAGGCACTACGCGGACCTGGAGGAGCGTCTCGGCTCCGAGGTCTACAACCTGACCGCGACGTTCATGCAGCAGGGCCCGGTGATCGCCCTGGTGCTGGAGGGCTACGACGCCATCGCCACGGTGCGCAAGATCGTTGGCAGCACCTACCCGGACCAGGCGCCGGCGGGCACCATCCGCGGCGACTTCTCGCACATGAGCCGGGGCGCCAGCGTGGCCGTCGGCAAGGCGGTCGCCAACCTGATCCACGCCTCCGGCAACCGCGAGGAGGCCGCTCAGGAAGTCGACCTCTGGTTCGCCAAGGACGAGCTGTTCGACTACAAGACGCTGGCCGAGACGTACATCTACTGATTCGGCGGCCTCCTGGGCGTCACCCCGGTGACGTCAGCCAAGTTCACCACCACGAGAACGACTGGCACGACACGAGGAGAAGAGCCGATGACGAGCACGACCCGTCTGGCCTCGCCGGCCGAGCTGGAGGCCGCCTTCCAGCAAGAGCTGGCGACGGACCGCTGGGCCGCCGCCGAGACGGCGTACGCCCTGGCGCTGCGCCTGCGCGACGCCGGTGAGTGGGACACCTCTCGCGAGTGGGTGAAGCAGTGCCTCCAGCTGCTGGAGGGCTTCCCCACCGAGACGGAGGACCAGGTGGCCACCAAGCGCACCGCCGTCGGCGGCGTGCCGCTGCCGAACTACCTGCACGCGGGCGTCGTCCGTGAGCGGTTCGGCGAGCTGGCCTGACGTAGGAACGGCCGGTGGTGCGGTCAGAGGAGCAGTAGCCAGCCGCACCACCGGCGACCAACCGAATACAAGATCATCTGTACCGGCCAGGGGTACCTCGGCGCCGGTGCGGCCCCATCCGCCACGCCCAAATCAGGAGAGGACGACCGCGATGGCCGTCGAGATCGAGATGCGCGCCCGGTTCGACAAGGACACCCACGACGCCCTGGTGGAGCGCCTGGTCCGTGACGGCGAGGACCTGGGCCAGGATAACAAGCTGATCCACTTCTTCGTCCTGCCGGACCAACTGCTCAAGGTCACCGACAACCAGTCCGCCGGCACTGCCAAGATCACGCTCAAGGACAGCCGGATCGGCCAGGGCGCCGCCTTCGGCGAGACCGAGTTCGCCATCGCCAAGGAGGACGTCGCCAAGGCCGTCCAGCTCTTCGGCGCGCTCGGCTTCGAGGACACCCGGCACGAGGCGTTCAACTTCCGCCGCAACTTCCGCTTCGCCGGCGTGGAGATCGCCGTCAAGTGGAGCGAGGCGTGGAGCTACCACGCCGAGTTCGAGGTGCTGCTGCCCGACGACGCCACGGACACCGCCCGCGATGAAGCCGCCGCCCAGATCCTCGACGCCGCCGCCGAACTGGGCATCGCCGTCATGACCGAGCAGGAGTTGGCCGAGTTCACCGCCGAGTTCGAGGCCAAGGAGGCCGCGCGCAAGGCTGCTGCCCGGAACGCCGAGATCCGGTAGGGCCTCCAACCCTCAAGACCACCGAGGGGGTGGGCCGCACCATGAGCACAACCCGCACGGACAGCCTGGTCGAGTTGGCTGCCCGCAAGGAACTGCCGCTCCACCAGTTCACCGACGCCGCCACCGTCGAATGGATCAAGGCCAACCGACCGGACTTCCCGCCGGCCTGGCCGCCGCCGCTGCGCCCCACCACGCAGACCCTCATCGAGCAGGCCGCCGTCCCCACCCGGTGGCTCGCCGAACCCCAGCTCGCCGACTCCATCCACGGCCACCGGCACGGCCTGCGCACGGCGGTCCTCGCCGCGCTGCTGGCCGACTGGTACGGCTTGAACGAGTCCGACACGGCCACCGCGGTCATCGCGGCGGCCGTCCACGACTCCCAGCGCCACCACGACAAGGACGACCAAGGCCACGGCAACCGCGCCGCGATCTGGCTGGCCGCCAACGCCGAGCTGGTCTGGACGCACTTCCGCCGCACGCCCCGCCCGAGCGAGGTCATCCGGGCCGCCACCGCCGTCCGGCTGCACGAGCTGCCGTACGAGACGTTCACGGCCGACGACCGTGCCGACCACGCTCGGGCCGAGCAGATCTGCGACCTGGTGAAGGTCGCCGACGCCCTCGACCGCTACCGGCTGCCGAAGCGCTCCTGGTGGCCCAACGCCAAGTTCGTCCGTGAGCCGGCCTTCGACCAGCTGCTGCCGCTGGCCTACGACCTGGTGGTCACCTCCGAAGAGGCCTTCCTCTCCAGCGCGTCCAGCGTGGCCGCCGTCCGCTACGCCCTCGCCGAGAAGGGGTTGGTGTAGCCGTGGACTTCCTCGACGCCTACGAGAGCTGGGCCGACGCGCACGCCTTCTTCGGCGCCAGCCTGGTGCCCACGATGCCCAACGCCGACGACCCGCTCGGCGTGCAGAAGGCCGCCTGGGTCGACCGGCTGTCCCTCGGCACGCCCAACGGCCAGCTGCTCCGCCGCAACGCGCTGTTCGACTCGCTGGCCAGCGGCGGCAAGCTCCACCTGCTGCACGTCACCCACGCCCTGGAGAAGATCAACCAGGACGGCGTGCTCTACCCCTCCGGCGGCTGCCTGGTCGGCAGCATCTACTGCGCGCCGCTCACCGCGACGGGCAGCGGCTTCCGCCCGCACAACCTCGGCTCCTACGTGCTCACCCGCGAAGCACCGGCCTTCCTGGCGAAGATCGGGCGAGCAGATCACCAGCCCACCCCGCTGATCTTCGAGCTGGACCTGCCGTCGCAGGCGTACCAGGGGCTGGCCGGCGTCGACTACCTCCGCCTCGGCGCGATTCACCTGGCCATCTACACCCAGCTCGAATACCTGCTGTCGAAGGCCGAGCGGCACCAGCTGCGCGAGACGGTGGTCAGCCGGGTGAAGAACTCGACCGCCTTCCTGGCGCTGGCCGCCGCCATCGCCTACCAGGGCGCCATCGTCGCGCCCACGGACTTCCTGCGGCAGCTCGACGCCACGATCCCGCGGCTGCCGATCCTCGGCTACCTGTTCTTTGAGGCGCTGTCCGAGTACGTCATGCTGCACTCGACCAGTTCACGTACGCGCCGACTCGCCGAGCTGGGGGAGCTGAACAACTGGCTCTACAAGGAGCTGCTGTTCGCCGTGCCGGGGATGATCGGCCGATTCGACCTCGCCAAGTTCCACGTGCCCGACCTCGCCGCCACCTTGGCCAAGGTCGACCGCACGCTCGACCCAGGCGCCGCTGCCGTGTTCCTCACCGACCGCATCAGCCACTTGGTCGCCGCGCGCCTGTTCACCCCGGGGCAGGCGCCGGACCGCTGGCGCCACACCAAGTGGGAGTTCGACAGCCTGGCCGCCCAGCTCGGTCCGCTGCTCGGCCACCTGATCCACCGCGAGCTACGGACGTTCGGCCGGTCGCCGGACTTCTACTTCTACTTCGACCAGGTGAAGGCGCTCCAGGCCTGGAACTACTGGAACCACCTCGACATCCCGGTGCCCTTCAACGGCACCATCCCCAAGGGCGAGATCGGCATCAACCCGGCCTACCCGGATCTCCAGTACCGGGTCTGGCGCGCCGACGCCGACGAGGCCGGCAACCTCCACCCGACCGAGCAGCTGGACCTCACCCTCACCCCGCGCCTGGTCGACCTCCGCTCCACTCTGATGCGCAACAACCAGTGGGCCACGGCCCCCGCGGTCGCCTGACCACTCGGCACCGCCCAGCTGGCCAACGCCAGCCCCTCCACCTCTCACCACGCCTACGAGGAGACGCCTGCCATGCCCACGGACATTTCTGGCAATCCGCCCATCGACCTACTCGGCAAGCAGATCACCGAGCTGCTGGCCCACCCGAACATCGGCCACGGCCTCGCTCGCACGCTGCGCGCCGCCGCCAAGGAGATCGAGGTCGGCCGATACCACCGAGCCACCCAGCGCGCCTTTCCCAACGGCCCCGACGAGCAGCCGACCAAGGTCCAGATCGGCGGCGGCAACCACCAGCTCGACGGCTTCTTCAACATCGACCTGGTGCCGCCGGCCGACTTCCTCTGGGACGTGCGCGAGGGCATCCCACTGGAGACCGGCACCGTCGAGCTGCTGTTCACCGAACACTTCCTGGAGCACATCGACTACCCGCGCTCCGCCAAGGGCTTCGCCCGCGAGGCCTTCCGCGTGCTCAGCCCCGGCGGACAGATCATCACCGGCGTGCCCGACGCCGCCCACGTGCTCAGCCGCTACCCGGCGGCACCCGTCGAAGCCGAAGAGATGATCGGACGCTGGTACGCCAAGCGCACCTGCCGCGAGGACATCAACACCTACCTCGACCTGATCAACTACGTCTTCCGTGACCAGGACGACGACCCGAGCTACACCCCGCACCTCTGGGCCTACGACGCCGAGAAGCTGAGCCAGCTGTTCACCGAAGCCGGGTTCACCACCGTCGAGCCCTGGACCTTCGACGCCACCCTGGCCAACCCGAAGCGCGAGTGGGCCAGCGTCTACGTCATCGCCACCAAGTAGGAGTTCGGCCCAACCAGAGCGGTGGCCCAGCTCCAACCGGGTCACCGCCTCGCCGGGAGGCGTCCGCAATGTCGCAAGTCCCCACCGCGCACAACCACCTGCTGCTGGCCGACACCCCCAACGCGGCCAGCTGGGCAAGGCGTCACACCCGTGACGTGCTGGGCCGCTGGCAGATGCCTCCCGACCTGATCGACACCGCGCTGCTGATCGTCTCGGAGCTGATCGGCAACGCCGTCCAGCACCCGGGCGACGCCAAGCAGCCCGAGTGGCTGACCTCCGCCGAGCTGGCCAAGGTGAAGGTGATCGGCCTCGACCTCCAGCTGCGCGGCCAGGCCGTGCTGGTGCAGGTCGCCGACCACGACAAGCGACCGCCCGTGCCGCAGAACGTCGACACCGACGCCGAGGGCGGACGAGGCCTGTTCCTGGTCGAGCACATGAGCAGCCAGTGGGGCTACTACCACCCGCCGACCGGCGGCAAGATCGTCTGGGCCGAAGTGCGCCCGAGCAGCCCGCGGAAGCCGCAGCCGGCGACCGCAGAGCCGCCGCCATCCAACCGCGCAGCCCGTTCCCGGCCGTTCAAGCCCATGACCAACGAACAACTCCCCGTTAGCGACCCGAACTTGATGGGTCGAGTGTTGGTGGGGCTCCGCAGGATCTGATGGGCAGTCGGCGTCGGCCCTGTACGAGTCCTGGGTCTACGAGGCCATCCACAGTCAGCAACCTTCACTCGACTCGCCCCGGCTCACTGCCATGATCCGCCCATTCGCCCGCCCGACCCTGATGAGGACTACCCGAAACTCTGCACTCCGCGGTCCTGGAGGGACCGGAACCGCTCCGGTCCCTCCAACGGCAAGAGCGCAGAGGCACGAGCTCAGCGCTCTCAGCCGGACGTGTCGACCCTCTCAGCTCGGGAGGAAGGCAGTCCGCCGTCCTCATACGGAATCAATCCACTCCGAGTAACCGCATCCCTGAGGAGTGCTGCCAGATCCTCCGGAACCTCGACCCGGGCTTGGAGGGCAGGTCCGGGCTTGACTATCAGCCTGATTCCGCTGTCCAGGAGAAGCTGCCGACGCCCTGCGGTGTCCCGGGCCTGCCAAGCCGTCGCGTACGTTTCGTCGGAGTCCTCCAGAATCCACTGCGCCGGCCGCTGCGGCAGGGCTTCGAGCTCCTCTCGCCGGTGGAGCAGCGCCCGCATGCGTTCCTTCCACTCGTCCTCGTCCTCGCGACCGACGATCAGGCCTTCGTCCTTCTCCTCGCGAAGGCCCTTGATCGCCCGCTTGACCACAGCCAGATCCTCCGAGTGGTCCTCCCCCGGGATGTACCGGCGCACTGGAACGTACTTGTCGCCGACCTTCGCGATGAAGGTCTCCTCGATCAGGTCCTCCAGCTGCTGGGAGGGCTGAGACGTTCCGCAGTTCGCCCTCCCCTTCGCGCTCCCGCTCGGGCAGTGGTAGTAGCTGTAGACCTTGCCGCTCGACTTCTTCGGAGCGTTCTTCTGATAGAGCGGTCCGTTGCACGCGTCGCAGAATGCGACACCGAGCAATGCGGACGTGGAGAAGGTCCGCGTCTTCTTCGTGGATCTGGCCGCGAGCGCGGGCTCCAGTCTGGCCCACAGCTCTCGGTCGAAGACCGGGTCGGCGATCCTGATCGGCAGCCCGTCGGCGCCGCGGGTCTCCTTGCCACGGTGGAGTTTGTACCCGCGCAGCGACGGGGTCCTGAGCAGGTCGGCGACGACGCTGGTGGCCCACTCGATCCCGTCGACACTCTTCCCCTTCGAGGTCTCGGTCTTCCCCTGGGCCCTCAGATGGCGCACCAGGTTCGTCGGCTCGTTGCGGCGATTCAGCTCCCCGGCGATTTCACGGAACGACCAGCCAGCGATGTACCACTCGGCCATCTCGCGCGCCACCCCCGCCGTGTGCGGCTCCAGGCTCAGGGTCTTTCCGCCTTCCGGGTGATCCACCACCTCATAGCCGTACGGTGCATACCCGCCTGGCCAGCGCACCGTCTTCCGCAGGAATCGGTGCGCACCGAGGACTCGGTCCCTCGTCCGCTTGAGTTCCATCTCCGCGAAGAGCGAGGCGAGCATCAGGAAGACCTTGCTCATCATTGCCGACATCGAGTCCTTGCCCTCGTCCCGGAAGTTCAGGACGATGCCGTCGTCCGAGAAGACGAGGATCTTGCGGTTGGCCTCCGCCCAGTGCGCCACGTCCGCGCAGTCCTTCGCCGAGCGGAAGACGCGGTCCACCTTCGAGAAGATCATCGCGTCCCACAGGCTTGCCTTCTCCCCCAGCCACGGGCCGAGGTCGGGGCGGTCGAACGGACGGACCTCGGCCGACACGTCCAGGTCCTGGAAGTAGCCGACGACTTCCCAGCCCGACCGGTCGGCGTAGCGTTGGCCGGCTTCCTTCTGCACCAAGTGCGAGACCTTCTCGGCCCCTTTGACCACGCTGACGCGTGCACCGACAACGGCTCTGAGCATGTCCGAATCCTCGCAGGTCAGACCCGGTTTCGCGTGTTGGGAAACTTCTGTCTCCCGCGACCGGGACCTTTTCCAGCTGGTGGACGACACGCGTGGTGTCCAGGTGATCTACCCGGTCAAGGGCGTCGGCAACGCCGAGGTCGTCAACGAGGTCTTCCTGCGCGAGAAGTACGGCGTCACCGGAGCCGAGTACGCCGACATGGCCGCCCTGCGCGGCGACCCGAGCGACGGCCTCCCGGGGGTGAAGGGCATCGGCGAGAAAACCGCCACCCAGCTCATCCGCGAGTACGGCGACCTCGCCGGCATCCGCGCAGCCGCAGCCGACCCGCTCTCCAAGCTCACCCCGGCCCGCCGCAAGAACATCCTCGAAGGCGCCGCCTACCTCGACGTCGCCCCCACCGTCGTCCGCGTCGCCACCGACATCCCCCTCCCGGCCTTCGACCCCACCCTCCCCCGCGAGCCCCTCGACCCGATGACCCTCGAAGCCCTGTCGGAGCGCTGGGGCCTCGGCACCTCCCTCACCCGCCTGCTGGAGACCCTCGCAGTCACCCGCTGAGAACGGAGGCGGTGACTGTCAATCCCCTGGTTTCGGTTACGTAGAGGCTTTCTTTGAGAGGCCAGGTCCTCCTGGTGGTGGCTGGCGCGCGCCTCGCTGATGATCCGTTCGAACTCCACCGGCGGCAGCCCGCCGGCCACGCTGTGGCTACGGCGTGGGTCTATGACCGCCGCCAGGTACAACTTTCCTTCCCCTATGCTGACTTCGGTCATATCGCCGACCCAGATCACGTTCGGCGAGACCGCGTCGAAGTGCCCGACCAGGTCGCGGGCGGCCCTGAGCTTGCCCTGCCGGGTCAGCGAGCGGCTCCGACGCGGCAGCTTGCGGCCCTGGGCCCGAGCTCGGCTATGATCTCGGCGACCGTGTTCACCGAGACGTTCCAGCCCTCGGCCCACAGGTAGAGCGTGATCCTCTGCGAGCCGTAGGTTCGCCCGACCGGCGGAAGAATTATGTGATCCGGTCCGCCGGCCGCGACCGCCTGGCCTCACGGTTCGTCGGCGCGGACAGACGATGGCGCCACTTGTAGTACCGCGCCTCGGAAACACCGAGCGCGCGGAACGAAACGGTGTGCGGGATGCCGTGCTCGGTCCTCTGGTCGCTGATCACCCCGACGAGCGCCGCCGGGTCCGCCACGGCTACTTCGCCCAAAGGACCATGCGGCGCTTGAGGACAGCGCGCTCCATCTCCAACTCCCTTACACACCTGGCCTGTTCATTGGCCAGCTGCCGCAGCCGGGCCAGCTTCTCACACTCGGATTCGCCCAGCGTGCCGTCACCGCCGGCCTTCCGCGCCCGGGAGACCCAGGTCGCCAGGGTGACCTCGTTGATCCCAAGTTCTCGCGCGAACTCCGCCGCCGGCTTCCCGGTCTCAGCAACGATCCGCACAGCCCCTCGCGGAAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP025394|1353930:1416764|1405873_1406416_-|WP_104815109.1|DBSCAN-SWA
MSNQPFLYVAVCASGIADDVSQLITAAQEEGWRVGVVATPNAMGFIDQAAIEQQTGYPIRSAWRTPDVPASLPPADAIAVAPATFNTINKWADGHADTLLLGILTESYGLGIPVVAQPYVNSAQAAHPAYAANVERLKAMGVLFGDYVPHKPKAGGGRDQYDWITPLRLLRPVLEAKSKA
>NZ_CP025394|1353930:1416764|1371683_1376795_+|WP_104815091.1|DBSCAN-SWA
MSPYATGGGGVTFERKVAVQYLAHLLLGDGAAELGDSRSVVGVDFQKAPDHSADDLVIHAARADESGPSLVLAIAVRRAPDLVQSNELSKKLICTLVQEVVNAPNDGIEYRAALVVAGRQDHAEQLAVLADEAVKQRDAPNFFGLVRTPRKFPVGVRTRLTHIEELVKHALTTLRATEPSPQLVEQHTWELLSRLTVLMPRLETPDDLDWAPVTNSLIPVARGADLYGATRLLERLIALADEYQPKAATVDLSLLRRDAHQVLDSTTRRHRQGWGALGHLHERALASVRDEIAAEDGSRTVRLDRSDTAAQLLQLVTPSAAVVASGESGVGKSALVVRTLAAAAQDADSVQVACINLRHLPGTTVELEAVLGTSLTALLGELSAPQRLLVIDGADALAEGKQELFRYLIDAAGQADVKVVAITANDARQVVHDTISDRRVGEVAGFEVPLLTDAQVTEVASVFDELSALAADLRSRELLRRPVVVDLLVRGGVKATPLSDADAMQHVWSRLVRRQGYPERGIPDARDIALLRLAALELGHGDALEVVGAIDPTALAGLRQDGLLRTDADDPFAIGPQFAHDEVRRYAIARLFLSAGHPTTKLVEAGVPRWALGAARLACQALLAGPDTPKSPLRGRFARLQQAFDDLVAAGHGDRWGDVPGEALLTLGAPDPVLREAWPMLRAEPSAGLRRLIRLVDQRLHDEAGLVRIIAVEPLIALLLDDEEPWRQGKHVQDILRDWLHAVIIAGTPAGYPLRVRLHDRLVAACAAADRRLSDEQAATAAAQAALPPEELEAERQFLEKQMLRFTGGSRRHTQRSARHELPREITDELMVELLALLGPDLGEDGEAVLRRVAHDAPAWVGPAVDEVLTGRALAMYRRGFLAELSVAYYLNEDEDGTGFHQDGIRRHHARGLGVTPLAAWYRGPFMSLFQTDFRNGVSVLNRMLNHAALARARTLAGLQRQYGAPIEDHALDDYREELDVAGVRRTYVGDEHVWLWYRGTGVGPHPCMSALQALEQVCDQLVEADIPLATLVAILLEDCANLAMVGLVVGLLVRHLERADRLLDRYLTEPVIWHLEFGRVVHEASGLGASSDGLTAPERRRWSLRETATMMVLRADDQRADELRLLGSGLIANARRLFEEEFGESAESTVQEQLATVRAWASGLDRGTYQAQQVEGGLEIQSTPPSDVVEALQARNVETARAREAMRLNVRYYVNPKTGKAEAIDSDELVADLAAARELLENPPDLGPSSQWDAPAAVAATALTANVVDGVDLPVDALRFAVDTLLRIGEDATSPRQFDSEEAYFEQGADRFAARTLPLLLTPAATPLRAQIDGKDGSTTYRQAAAAASKLARSLPNEVRVNLARGLDHVWQAACTAGNRSCHHETAFELAVETMRDCTFGDWDPDSGRRKVTALEDPIAHSLARAAADCIYEARLDGAIRALGPAAAASICVSASARELLAVLLATHRRSLLASEDDMDSRGTHALIAARALLALASTGEDAPVFEHIDAYADNPTLLGSFLGALSSAAEESADRAATARRMWPTVVAHVIALQASGHTPFEGRHEYRSSLASLLPNPAAEVAYLYREVQSKPIVWWEPLAWQDTVAQWLPMARGHAACVDQLIGFIKPLPAENQVHVGLPWVADLVLADPSRVAKRTYLLPSWLIELRQAVADAGMTADWQRVVDALVVAGVSRLAPYSE
>NZ_CP025394|1353930:1416764|1370246_1371038_+|WP_104820582.1|transposase|DBSCAN-SWA
MSDAEWAVVRPLLPVPGWLRGRGGQPEAYCHRTILDAIRYLVDNGTKWRAMPADFPPWDRVYAFFRRWRDHGLVRELHDRLRRKAREQAGRDPEPSAGVIDSQSVKADAVVGRDSRGFDGGKLINGRKRHAVVDTLGLLLAVMVTAADIGDRAAAQVLLAQVAAAHHRLALVWADGGYTGSLVEYGFTVLALVLAIVKRSDDMRGFVVLPKRWIVERFFAHLMRSRRLVRDFERSTGSAEAMVYWSATMLMTRRLARPRPSRA
>NZ_CP025394|1353930:1416764|1362488_1363202_-|WP_104815085.1|DBSCAN-SWA
MDRKNIPNPGFAEDDGTADPRLTAALAAWAADRTAETERALLTALTPSRLMVPIVALLGEVEVDANGHKHEKTSDMAVPVIEAPDGRRALPAFTSLETLARWRADARPAPVAAPQAAVTAYSERAGSLLIDPAGPVTYELTGAPMRAVAENRPYLPPLKDPEVEAAVRAVLAVEPAVRRAELRPGTETDAVLALALAEDLPEEEIRALAGRLAAALAADPILRVRLTRGLDLALLGA
>NZ_CP025394|1353930:1416764|1388092_1389445_+|WP_104815098.1|DBSCAN-SWA
MMNEVPVGWRIVRLADVLSEPLVNGRSPRPGEGGLPVLRMPALRAVTVDFTQSKSSDRVDNGHAILLAEHGDVLVGRVNGSHSLVGEGALVDGPPAPTAIPDTMIRVRVRPDVLDPRYLANLWKSPVMRRQIEARARQGAAAIWRINQRDLADVLLPLPPVGEQRRIVGLLRDQLTRIDATTIRTHSALDQADVLSRTLTARAVRGGLTDTARVPADLPRVAGAGDGALPDLPERWRWTRLHDVAEVTRGITPPGTQEWNPADTDVSSLRVANVQRGHLVLDDVRTIRLPPSRAEAARLRAGDVLLTGGGSIDSLGRGWIWEDQLPHCVPHSHVFRARITTHQLHPVLLAWHANGLGREWCHRNATQSAGPASISLARIRLMPVPVAPVDEQHHLVAVVQAHTAALNAACAAAERALEVAGRLRRNLLERAFTGHLSPPLSPSGQQEFVL
>NZ_CP025394|1353930:1416764|1364564_1364939_+|WP_104815086.1|DBSCAN-SWA
MEAELVALATSGATTMVNLMATNLWTTAQGRFAALFGHRAEAVAEELEEVREAGGEAEDLIAEWRPRLQRLLAADPAAAAALRALVEEYAPPAEAHGGGVQNTISGGEFHQAVIQTGHIGSVKL
>NZ_CP025394|1353930:1416764|1360452_1360647_-|WP_104815083.1|DBSCAN-SWA
MPKQKTHSGSSKRFKITGSGKVLRERAGRRHYLEHKPSTLTRKLAGNAEMAPGDAKKIKKLLGL
>NZ_CP025394|1353930:1416764|1403934_1404690_+|WP_158702056.1|DBSCAN-SWA
MTNREPRTAHADAPLAQLLRSRPGYVPPTVGERVVVVADLLAPSRHPRAVMNLLRFVGDWQPDRVVVMSARQHGSTHKGSECATSTLGRLRAIYSGDIVIQAGVGAGRDALTVGSCSCWHPVISDLGLAVTAGIQPVAPGWLSLSATGPGASRYPGALAILLARGFGHSIICSGTSGLALIGEIPTDDPTADTLWGFEIGTLRRTAPSTASSFRPAMGFGVVDSTTGIAEPTAVAISRSGAFTFDGVTYAA
>NZ_CP025394|1353930:1416764|1410634_1412017_+|WP_104815114.1|DBSCAN-SWA
MDFLDAYESWADAHAFFGASLVPTMPNADDPLGVQKAAWVDRLSLGTPNGQLLRRNALFDSLASGGKLHLLHVTHALEKINQDGVLYPSGGCLVGSIYCAPLTATGSGFRPHNLGSYVLTREAPAFLAKIGRADHQPTPLIFELDLPSQAYQGLAGVDYLRLGAIHLAIYTQLEYLLSKAERHQLRETVVSRVKNSTAFLALAAAIAYQGAIVAPTDFLRQLDATIPRLPILGYLFFEALSEYVMLHSTSSRTRRLAELGELNNWLYKELLFAVPGMIGRFDLAKFHVPDLAATLAKVDRTLDPGAAAVFLTDRISHLVAARLFTPGQAPDRWRHTKWEFDSLAAQLGPLLGHLIHRELRTFGRSPDFYFYFDQVKALQAWNYWNHLDIPVPFNGTIPKGEIGINPAYPDLQYRVWRADADEAGNLHPTEQLDLTLTPRLVDLRSTLMRNNQWATAPAVA
>NZ_CP025394|1353930:1416764|1367768_1368869_+|WP_104815090.1|DBSCAN-SWA
MSDHEHDHTDHSEHAQHSQHSHDEHGDHSGHSHGGHGGHGGHGGHSHGVAADADRRWLVSALTLIVAFMAGEVVVGFAARSLALISDAAHMLTDAASIVLALIAMRLSARPAKGGYTYGLKRAEILSAQANGVTLLVLSAWLGYEAITRLLDPPEVEGSLVLITALVGIVVNIGATWCMSKANRSSLNVEGAFQHVLTDLYAFIATAVAGLIVVLTGFTRADAIASLIVVALMLKAGIGLVRDSGRIFLEAAPAGIDPDALADRLVATPEVVEIHDLHVWEITSGQPALSAHILVAPGGDCHAVRRGLQRRLATDYRITHATLQVDHVGEDEDQHLLQITPAGAATGPDHCADSHGPVHRPGPHDH
>NZ_CP025394|1353930:1416764|1409247_1409829_+|WP_104815113.1|DBSCAN-SWA
MAVEIEMRARFDKDTHDALVERLVRDGEDLGQDNKLIHFFVLPDQLLKVTDNQSAGTAKITLKDSRIGQGAAFGETEFAIAKEDVAKAVQLFGALGFEDTRHEAFNFRRNFRFAGVEIAVKWSEAWSYHAEFEVLLPDDATDTARDEAAAQILDAAAELGIAVMTEQELAEFTAEFEAKEAARKAAARNAEIR
>NZ_CP025394|1353930:1416764|1363303_1364497_+|WP_104820684.1|DBSCAN-SWA
MPTASDRARYDRATAHLDAPLAIVDLAAFDANAADLVRRAAGKPVRVASKSVRCRALLERVLAMDGFAGVMSFTLAESLWLASEGFEDVLLAYPSADRTAFAELTADPKLAAAVTVLVDDPRQLDLIDAARGGSEEVRVCLELDTALHLLGGRVRIGARRSPLRTPEDLADLAELIQRRPGFRVVGLMAYEGHVAGVGDRLAGRPVRSRMIQLMQAKARAELADRRSAVVRRVRQVADLEFVNGGGTGSVESTVAEAAVTEVAAGSGLYVPRLFDNYRSFQGRPAALFAQPVVRRPGLGVVTVLGGGYPASGAAGPDRSPVPYLPEGLRYDPQEGAGEVQTPLLGSAADDLLIGDRVWFRHAKAGELCERFAELHLIEGDRVTATVPTYRGEGRTFL
>NZ_CP025394|1353930:1416764|1393905_1394091_-|WP_168219559.1|DBSCAN-SWA
MARLSSAISFFIALICADSSVVVPGRCPESTWSRRTQLRNVSAEPMPSFSATARSAADSFG
>NZ_CP025394|1353930:1416764|1394163_1395315_+|WP_104820687.1|transposase|DBSCAN-SWA
MARMGRPGMSDAQKRELWDRWKAGESISEISRALGRPPGSIFTIVKANGGYVPPVRRRRPGSLTFAERESISRGLARGDSIRKIARTLERAVSTVSREVARNKGAKHYRAVDAEDRAWDRTRRPKPCLLATNEPLRALVAEKLTEDWSSQQIAGHLAKTQAVGTGIRISHETIYKSLFIQARGVLAKALQKHLRSGRPTRRNIHNTVTGQWRSQIKDTIPIHERPAEADDRAVPGHWEGDLIMGSGVTQVATLVERTTRFTMLVQLDARDTATVTARVSTQMLQLPDQLRKSLTWDRGMELAAHKSVTAATGMAVYFADPQSPWQRGTNENTNRLLRQYLPKRTGLGHLTQADLDTIARRLNTRPRQTLDFDTPADRLEALLR
>NZ_CP025394|1353930:1416764|1392873_1393746_+|WP_104820686.1|DBSCAN-SWA
MPGHPGYWWLAYDVSNYRIACKHCNSGGARYNGVPEGRAKGSQFPLLAGPRARTSLDDLEREQPLLLDPAHHGDPDLLGFDTAGYARRSNTPYSSAEADSGLCRADETIRILALNDSRIVPLRSRLMQEVGVLARFGDAPEIQALIDAKVEPQAQWSAAAATALALQRACNRPIAAPAQPATTPVVTPVLDPRRSRVDLRDLLEYLDPDDLKAGITLTGRYNRTVYQATLKSDGELDVLGRLWRTPTTAARVATGSRQIDGWDFWRLTIAGVEQTLAEFRAKHFPPATRP
>NZ_CP025394|1353930:1416764|1356443_1357565_-|WP_104815080.1|tRNA|DBSCAN-SWA
MSAPNKSYDPVEVEALKPEEVERARDEAVAAFAAAATLEELKAAKVAHTGDRSALSLANREIGALPPQAKAAAGKLIGQARGAVNQALAKRQVELEAERDARVLVEEAVDVTLPYDRTPRGARHPLTTLAERIEDTFVAMGYEVAEGPEVEAEWLNFDALNLGEDHPARSMQDTFFVQAPDGSADSGVVLRTQTSPVQARTLLDREPPVYVVCPGRVYRTDELDATHTPVFRQVEGLAVDEGITFADLKGTIELLVSKLIGDGLELRWRPSYFPFTEPSAEIDLQCFVCRGESIGNPDKPCRTCSSEGWIELGGCGVVNPRVLVACGVDPNRYSGFAFGLGLERILMNRHNVADMRDMVEGDVRFTLPFGMEI
>NZ_CP025394|1353930:1416764|1397473_1397914_-|WP_158702055.1|DBSCAN-SWA
MIIEAILQGMKTELHEIRQVTVSRSGPLPDARELQSYEQVHPGAANRILSMAEREQRHRHDMEERIVTQPFRLARIGQGCGLAAVLLLGALAAYLAYLGEGGLAAVVAALDIAAIVTVFVTGQAAARRSDEDDSEATEEPSEVNQE
>NZ_CP025394|1353930:1416764|1416500_1416764_-|WP_174805624.1|transposase|DBSCAN-SWA
MPRGAVRIVAETGKPAAEFARELGINEVTLATWVSRARKAGGDGTLGESECEKLARLRQLANEQARCVRELEMERAVLKRRMVLWAK
>NZ_CP025394|1353930:1416764|1384455_1384761_-|WP_168219558.1|DBSCAN-SWA
MSFVWGGVQEHVGQGSATPAQRRSCSWSTAHGPETILIAVKEDGTQLPLPEASLAFVAVTGLLQTVPDGADSDGDRGSGGDWVPLIVYGFITSIDGPPLRF
>NZ_CP025394|1353930:1416764|1378404_1378572_-|WP_158702598.1|DBSCAN-SWA
MKAEIGTRTWPDRATARADVFAFVETFYNRRRLRKHPIWSYLTPHETRQRHTLAA
>NZ_CP025394|1353930:1416764|1404788_1405193_-|WP_104815107.1|DBSCAN-SWA
MTEPTSTKPGIAAAIVVQDGRVLMVQRRVKEGELSWQFPAGEVEVGESPEAAAVRETAEEVGLMVKAVHPLGERVHPKTGRQMSYTACEVVSGTATVVDTEELGALAWITREQIPEFVPYGLFEPVQVYLDAAM
>NZ_CP025394|1353930:1416764|1396520_1397360_+|WP_104815103.1|DBSCAN-SWA
MDEDRTATWAEGTSADLVADAHALGVSSVSTRMVTAWVEEGLLASPEPRKTTAHGSDPRVFPPEQRELFTKLLEARERSPLGRVPQRSIVRVVLYLWLIDDSVVLTPQARRAWRTHARATGKQTAARRSETARAIVASLAHPSATIPQRRAAQLVIEEGERTGRIDLPRLTSVLTELCSPWPAQPGAPRIERAIPGPFGPVTVQHHIAMWYARHQAVRQLRNEEVNEAALIGCAPSTAPNGPTTKPVGRLWLPRPERSPRLSPSPRLWRAARSRRSTPS
>NZ_CP025394|1353930:1416764|1370994_1371540_-|WP_104814471.1|DBSCAN-SWA
MPSVVGLLEQRELTARRRVDELREEADRIQAELVAAEREWSEWVIARSRVGEVLSPGEGDIAGPDAVEKPSDRGEPPALPASSAAAKPKSVVPMWRAGLARSALSADYQRIVQALADRGRLGQGPLTCQEMAACFGLDPVPAKIEALRSKAKRLTARGWLVEPEPGRFTLAMALAGPGGGS
>NZ_CP025394|1353930:1416764|1413710_1415309_-|WP_104815117.1|DBSCAN-SWA
MLRAVVGARVSVVKGAEKVSHLVQKEAGQRYADRSGWEVVGYFQDLDVSAEVRPFDRPDLGPWLGEKASLWDAMIFSKVDRVFRSAKDCADVAHWAEANRKILVFSDDGIVLNFRDEGKDSMSAMMSKVFLMLASLFAEMELKRTRDRVLGAHRFLRKTVRWPGGYAPYGYEVVDHPEGGKTLSLEPHTAGVAREMAEWYIAGWSFREIAGELNRRNEPTNLVRHLRAQGKTETSKGKSVDGIEWATSVVADLLRTPSLRGYKLHRGKETRGADGLPIRIADPVFDRELWARLEPALAARSTKKTRTFSTSALLGVAFCDACNGPLYQKNAPKKSSGKVYSYYHCPSGSAKGRANCGTSQPSQQLEDLIEETFIAKVGDKYVPVRRYIPGEDHSEDLAVVKRAIKGLREEKDEGLIVGREDEDEWKERMRALLHRREELEALPQRPAQWILEDSDETYATAWQARDTAGRRQLLLDSGIRLIVKPGPALQARVEVPEDLAALLRDAVTRSGLIPYEDGGLPSSRAERVDTSG
>NZ_CP025394|1353930:1416764|1405185_1405836_-|WP_104815108.1|DBSCAN-SWA
MDVVVSWTGRSACWLQEALRDTNEAFAARLGIAVRTVASWHKSPELVPRTEMHQLLDQALEAAAPAAQKRFALLLTESTGSQAAQALRVAVAVVVRGTDVLLVCRRDDESAGIRWQFPAGVIKPGGSPASAAVRETLAETGVHCAVRQDLGGRLHPSTGVWCEYFLAEYLVGEAQNQDKIENADVMWVPRNAVPRFIPVDTIFPPILAALEESQND
>NZ_CP025394|1353930:1416764|1361994_1362372_+|WP_174805505.1|DBSCAN-SWA
MSAQPTDPTDLAEDQIGFDDLTRDIAEVPAVEVITTVAVHLMSAAAVKCGLAEGGEADKDLDEARKLITALAGLVTAGAPEISNFHAAPLRDGLKSLQLAFREASLVPDAPGAGPGEKFTGPVYS
>NZ_CP025394|1353930:1416764|1378568_1379300_-|WP_158702052.1|transposase|DBSCAN-SWA
MRERPASEAYRFIAAEKATYPVTLLCRVLGVPRSSYYAWAGGQEARRARVRADDALVDEITAVHLASKGAYGVPRVHAELRRQGHVVNHKRIERLMRERGIAGIIRRRRRSLTRPDKQACPAPDLIGRDFTATRPGTRLVGDITYLPTGEGRLYLACWLDLASREVVGYAMAGHQCTDLVVDALRMAHARGRLEAGCIAHSDRGSEYTSTQFRTTASELGTERAPDAPARARTTPRPRASGQY
>NZ_CP025394|1353930:1416764|1379403_1379577_-|WP_104815093.1|transposase|DBSCAN-SWA
MSNKQGKRYSEEFKRDAVRLARSSSKTVTEVARDLGAAPRACGAGSSETRSTSTRSP
>NZ_CP025394|1353930:1416764|1389441_1390941_+|WP_104815099.1|DBSCAN-SWA
MNPTVSSRPGHDQALVDRLWNYANVLRDNGTSGLELIEQLSSLIVLKRANEQRQRPLNGRDILGFDAWEQLTSTERDYLIPAYEQILKQLAARPGTLGLLFRRAQNRIPDPALLHRLIVDVVDRYQWSSADIGAVFEALLARMSTDTKTGAGQYFTPRPLIEAIVQCVQPGIDDTVSDPACGTGGFLIKAFDYLVDHFPSGVTAAQRKRLDQGAFFGTELVDATARLATTNLILHGVTRADEIHPCITVGDALVRPPVRRATLVLTNPPFGRRSTSEEPYREDFWTLTTSRQLNFLQHIHSLLETDGRAAAVVPDSVLFEGGPGELIRQRLLSACDVHTLLRLPTGVFYAGGLKASVLFFDKPEPRPDGSPSTTRLWVYDLRSPHTSTAKSMTPAGPDYSDFVSAYRPGRPRSERVETPLFRSFAVQDLLARHGVNLDLQVAEPPPGPFALEEPEADLHRMAQEITAALGTALAEFASLTEALRPYGVHADGPDREAER
>NZ_CP025394|1353930:1416764|1366945_1367743_+|WP_104815089.1|DBSCAN-SWA
MTTRPVIGISTHLTDATWDHWSAQRAVLLHERYPRQVQAAGGVAVLLPPDAPEHAPEAVARLDALVIAGGPDVNPALYGAQPHPRTVANAPERDRWEAALLRAALAAGLPLLGICRGMQLLNVVRGGSLIQHLHEPGPHLGSPEGYGRHAVRPVAGTLLAGLLPEDSVSVPTYHHQAVERLGVGLSVSALAEDGTVEAIEAAEGFTVGVQWHPEQGADLRLMQALVRAARRPVPATTTVTSAAFGSSSELGFTSGAGRLRPATER
>NZ_CP025394|1353930:1416764|1353930_1356444_-|WP_104815079.1|tRNA|DBSCAN-SWA
MRVPLSWLREYVDLPAGETGRDVAARLVRAGLEVETVEQIGTDLKGPLVVGQVLSIEELTGFKKPIRHCFVNVGDANGTGEPQEIVCGARNFAVGDKVVVVLPGAVLPGPFPIAARQTYGQTSAGMICSARELGMGDDHDGIIVLPPEYEVGTDAIELLQLVDEVLDIAVTPDRGYCLSMRGVAREAAAAYGLPLADPALLDVPPANSYGYMVKVADPTGCDRFVARTVTGVDPAAKSPIWLQRRLQKSGIRPISLTVDITNYVMLEVGQPLHAYDRERVDGPIQVRRAVEGEVLTTLDGTKRKLSAEDLLICDNSGPIGLAGVMGGASTEILDPVTDPETGEVTGSTEIIIEAAHFEPVTIARAAKRHKLPSEASKRFERGVDPEAARAAAQRAVDLLVLIAGGTAEAGVTDIAAPHPLRTIAIDADLPDRVAGTEYGRETVTRRLQEIGCTVAGADILEVTPPSWRPDLTDPYDLAEEVIRLEGYDNVPARMPTVPPGRGLTEAQRFHRRTGVALAGAGYVEVNNYPFLGEAAFDALGLEKDDERRRTVKLVNPLNDEEPALRTTLLPGLLGALRRNIGRGNTDLAIFEAGTVFLPKAELRVAPRLPVDRRPTEEELATLNAALPHQPRRVAVALAGERLPSGWWGKGAPAGWADAIEAARTVASAAGVELTVRQGRTAPWHPGRCAELLVGETVVGHAGELHPRVIKALNLPERTSAMEIDLDLLFAGGEQRVSGPTVSGYPVATQDVALIVDSAVPAAEVETALRSGAGELLEAIRLFDVFTGEQAGEGKKSLAYSLRFRATDRTLTAEEASAARAAAVAEANARTGAVLRGA
>NZ_CP025394|1353930:1416764|1409870_1410632_+|WP_104820688.1|DBSCAN-SWA
MSTTRTDSLVELAARKELPLHQFTDAATVEWIKANRPDFPPAWPPPLRPTTQTLIEQAAVPTRWLAEPQLADSIHGHRHGLRTAVLAALLADWYGLNESDTATAVIAAAVHDSQRHHDKDDQGHGNRAAIWLAANAELVWTHFRRTPRPSEVIRAATAVRLHELPYETFTADDRADHARAEQICDLVKVADALDRYRLPKRSWWPNAKFVREPAFDQLLPLAYDLVVTSEEAFLSSASSVAAVRYALAEKGLV
>NZ_CP025394|1353930:1416764|1385045_1388096_+|WP_104815097.1|DBSCAN-SWA
MAQESSELESRFPDLALASANFGFLLPYEPLLVLHGAACEARASAAPADSVAAARQFGEVLAVKLGQLTGVRLPVGDQSARLQTLARAGVLTAQVLAAFKDLHGFDGGELDEEETAAHLLDCCFTLAVWFFRALTGDAEPMAFVHTEASDLRVLAQQVAVLEAALPRLRREFDRVAPASLSAAEREQLIVSARDASYEPLREADIASGVQRRLAKAGWDVLGAGAEDELNRSLGCVLVGPRLAGGHRADMLLTVGGQVVGIIECKRDGTDLTDAMEQAGALAEAATGSSPWPVWRSPLPYRYVSDGRRLLFCDANEPEPHPRLVSGFHQPRTLARWQREAEADGAAPTYRARQAAYLQRQDEGFDQLRIAQRRAVRAIEQALAAGQRRALVQMATGSGASFTGVFTAYRQLHYARAGRILFVTDRKLAVHQLIAQLSQFSMPDGGRPLDDVYHVQELTAHGLAPSASVAVATVQRLSAMLADTPAPEDGSESVAAYETAERQAHSDATPLEVSYCEALPPDAFDLIIVDDCHRALYGQRRALLEYFDAPVVGFSATPTATVLGFFKGNLVESYSYEQAVADGVAVDYSLYQIQVDGDRQPAFATPVDAVGVQARSSRRARYEDLDDELAFTAGQGPARAVPSERLAKVVTAFRNALPTLFPDRMQHGSGLLAVPKTMVLAQDGLHADEVVERVRDVFGAGDVFCQRITPRDAYAAELLREFRTTPQFRIAVVTDLISGNSDMRVMECLLILREVRSAAYYEQLLAMGTQTISSAELRAVTPGADAKAQLVVVDAAGASRHLQPLVNVTDASGQRGRDALERLLHRATDGRATPQETAELAVRLARLIPALSDADGAEIRKLAGRPLQELVTRLLDSVNSDHLASLRRAGGKRAVEDERREALNPLTEDLQLQEVLLDLYDRPTPAPGTTSGSRGRRQDTTVGRRLDEFVERSGPFNSAQLWWIEKIADVVATETRFDPAYLDSVPFSARGGTDGFLDAFGPDAAICLLDELRRALA
>NZ_CP025394|1353930:1416764|1412089_1412830_+|WP_104815115.1|DBSCAN-SWA
MPTDISGNPPIDLLGKQITELLAHPNIGHGLARTLRAAAKEIEVGRYHRATQRAFPNGPDEQPTKVQIGGGNHQLDGFFNIDLVPPADFLWDVREGIPLETGTVELLFTEHFLEHIDYPRSAKGFAREAFRVLSPGGQIITGVPDAAHVLSRYPAAPVEAEEMIGRWYAKRTCREDINTYLDLINYVFRDQDDDPSYTPHLWAYDAEKLSQLFTEAGFTTVEPWTFDATLANPKREWASVYVIATK
>NZ_CP025394|1353930:1416764|1358926_1359787_-|WP_104815081.1|DBSCAN-SWA
MQSTDTPLLTSLRSPRVIAARKLARRNQRSKERRFLAEGPQAVREAVAYGRPAGSSEHVVVEVYLTPEAAERHADIVEAALTAGLPVLTATDEVIAEICDTVTPQGIVALCRFLDTPFEDVLAARPKLVAILAHVRDPGNAGTVLRTADAAGADAVILTDASVDPYNPKAVRASVGSLFHLPFAVGVPVEEAVGRLRAAGVRVLAADGAGQRDLDQELDEGTLGAPGAWVFGNEAWGLPEETRALADEVVKVPIHGHAESLNLATAAAVCLYASARAQRSPGGCRT
>NZ_CP025394|1353930:1416764|1383241_1384420_-|WP_104815096.1|DBSCAN-SWA
MTDPLDIPAPDNTGTVTLRRFTYQEKVAARYVIAMLGDGGSIHHVTCEHIEDVVIATDHPANRSDVLWDFLQVKTKDDPTPWGLSDIIAKGALKSLWRTYLAVRARGLEYLLTVAVEGFLDPADDALTALARGAGADHPKCLARVSKHLKAQEADVSACLSFVRVRTMPRREHIDDQSLASLTELAPAVSVGEQRAVYLEVLNRVHEAMQGQAGASWKEKLGVEPPSEALLRKRLAPSSVYDLGQRLRRPDHVLLAAYSERIDAVETNLVRKLRRGGASEEMIHEAQFLRSEADGRRLSDLALGAWPEDPRVEQDLDTRLLITATRIARRHQDRGHRPADHIWDDLMQEINSTASELDRRPLYAKDPLLLMGRACSVSDECHFGWGVATSDG
>NZ_CP025394|1353930:1416764|1395319_1396297_+|WP_158702054.1|transposase|DBSCAN-SWA
MSPPRVSSRPSSTGHIFARSVRRRAPGPLRRRRADLPSAHRARLQHRPLHLLHLQQPHPSARSVRDTELKELITAAYEDNFRVYGARKIWRELNRRGHAVARCTIERLMRDLGITGAVRGKRVVTTVPDPSAERAPDLVDRDFVASAPNRCWVADFTHVAAFAGVVYVAFVVDTFSRRIVGWSAATTKQTRIVLDALEMALWQRDRDGYPPRRGELIHHSDAGSQHTSFRLAEHLDAAGIAASIGSVGDAHDNALVESTIGLFKTELIKPRRPWPTLSQVELATAEWVDWYNHRRLHGEIGHVPPTEYETTYHLTTAKPQVTTTS
>NZ_CP025394|1353930:1416764|1360787_1361549_-|WP_104815084.1|DBSCAN-SWA
MSTEPRINDRIRVPEVRLVGPSGEQVGIVPLAKALELAQEYDLDLVEVAATARPPVCKLMDYGKFKYESAMKAREARKNQAHTVIKEMKLRPKIDPHDYDTKKGHVVRFLKQGDKVKITIMFRGREQSRPELGFRLLQRLANDVQDLGFVESSAKQDGRNMIMVLGPHKKKTEAMAEARAIADARKAERQGRNSGADDQAAADDAALEAENAAAEAEADEIDDVEDAEETAEVTEAAEDAAEVEKPAEATQDA
>NZ_CP025394|1353930:1416764|1408796_1409096_+|WP_104815112.1|DBSCAN-SWA
MTSTTRLASPAELEAAFQQELATDRWAAAETAYALALRLRDAGEWDTSREWVKQCLQLLEGFPTETEDQVATKRTAVGGVPLPNYLHAGVVRERFGELA
>NZ_CP025394|1353930:1416764|1390975_1392616_+|WP_158702053.1|DBSCAN-SWA
MRLLRLRLPSYQGLRHFELDLTGALDGGHAIATLIGPNGGGKSRALHALAEIFGALHRPGRRAAFAFELDYEVHDRTVRVVQTSPDTSPELTVDTSLGRPIRAAREVWAQHLPDHVFGYQAHAQAPWSSEFDQHRLFAARLVGQWRRQWMTDFDQWRAHHAPNEGELWTEQLTLPINCPLYTPVFLCTPAHLPLLLLAQTTHWSDSFGTYLRRHSYLQRVTSAVLRIRAPRAARAPHLAALPYWGLGGPARTLFAAAAESGRFGLIPDADPVDGAGSPADGFQIVLGTAEDVRAFRNLFDSDLSMFGLLATLLDAGYLTVDVRLEKPGALTVGLNDLSSGEQQLLTILGLLRLQRAHESLFLLDEPDSHFHPEWSRRWYSSVRSVLGPHQHSQFLTATHEPLLVSNMTREQIRVVTTDEEGWATAVLPRANPRGQGAGGLLTTDLFGLPTQLDEHTQELIDRQYALLPEADGDPVKQAALRDVTAQLDAMDFPTSDRDPLVAALLAELHRRRLALLEAAQGPNPPSPEQLQTLVAELFHERFSSVI
>NZ_CP025394|1353930:1416764|1406412_1407693_-|WP_104815110.1|DBSCAN-SWA
MSEAVPAAIDARQIGSVIRRARVIAARSQHDVASKLGYHQSKLSRLEKGAGTDDVRILRAVAAELDIPLESLGLTASPSSTDLRTDDMQRRGFLAASVVALAVPAARPHTASLELVQALLPTASGLADRQLLAEATLRQELSKARRLLYGCRYTELEALLPALLTALRRAQHDAPDSLMLASMAATAYQTTVSMLIKLGDTGNAWLAVGRAMSEAERSGNPIVLASSVRVQTHLMARERHTAPAVTMVQHTADQLGSHYDQREPGDLAAFGLMLLRGVTAASTGGDRSTTTELLDQADEVARYVDRDHPDAWANFSPTNVALHRVSAAVALGDAGAAVEAARPLLRRRIPAPERQAALWVDLARAFNQQGKLSEGYRALRIAERHAAEDIRRRPDIRELVADMTARDRRGALPELRQFSRELGVRP
>NZ_CP025394|1353930:1416764|1398465_1403490_-|WP_104815105.1|DBSCAN-SWA
MTIHKLTAGNGYTYLTRQVAGGDVQRQRGQSAEEYYTQKGNPAGVWLGRGAPLLGLDGTSVTEQQMKHLFGLGQHPDAERIIAEHLAAGVRADMDGDQLKAVQAAAIKAATLGRKYPEYEPLDPFAKRVQRRLAVIRKETRRTPTSAEVKKVQQEESRRQRAAVAGFDLVFAPVKSAAVLWALDERPGVRAAVREAHEAARDAALELLEEHAAHTRTGSTGQAQIDTKGLVAVAFDHYDSRAGDPNLHTHVVVANKIQGVDGKWRSLDARGLLAMTVATSEFYNSRFETELTARLGVTFEAREDAVAKRQPVREIVGVPLEAITHFSSRRTEIEARYEQLLREYRRDHGHDPSRGMTHQLARQANLDTREGKKAARSLEEMRADWTSTVTTAHGQDVVQRVMAAVPAPESIPATARQEEPKPVEIPTLAAAVITAVGEERAVWTVWNLRAHAERLARSEHSTTSTTEHRQLVEAIVTEAVSPAHSVRVDAPALLDEPEELRRANGDSVFVQHASDRYTSTAILDAERRLVAAALTPVNEGLNPAFVGAAIDGFEARHRALDEGQRVLVTAFATDTRLVSLGLGPASSGKTTAMQAYVQVANQAGQRVVPLATSAASAAVLAKDLKQPAENLHKFLWEHTGGTYAAQLGSGQNVPSNRAGFVLNPGDVVLVDEAGMAGTFNLDRLTRIAAERGASVRLLGDYRQLGSVEAGGALRLIAAEAGAVELTTLHRFSNKDEAAATLKIRTGNSSGLDFYFANQRVVGGSRTAMVEAAYEGWKADMLAGRTTLISARTGTDVTALSARARDERVAAGQVETDGVLLRDGNRAGRGDWIVTRDNNRKITTNRGADFVKNGDAWQVLKRYDDGSLKVRHLEHRGRLTLPAEYVAAHVQLLYASTITRSQGGTVDTAHPLVTDDTTREELYVQLTRARHTTTLYTATHELLPFDTDEQLDKPKNDPDSFAAREVLERVLAREGAQLSATETIRGAQEDAASLATLAPRHQHAVETLTTPYYHQLIHRLFGPALAEQITTDDAMTAVTRALRAAETVGWQPERLLAAATWRGDLNPADSPAQALAWRLNTITDDRPAPAHLNAPTTADTTRYATLVAQLTGLPAHRLDPETATEQPVALHIAPAAAQAPDAHPHVPADTLTRYATAATALNTTTDTVTAHPQWPHLAGALAAAECTGRDTTTLLTTAATQTTGASDPVTALTRAARTTLATDGIPEHHQQTPETLRHQALTADVLGAQHATRALGESTWPALTAALRRAETAGHEPATLLRQVAEQYPLTGTDSLSQVLAWRIGRHLAADAPAAAAQQGDGAEAELWRTLAWTLKTIENTGTPAETALTGATGRTALPELLQHAQQQALAHTRAASGRADLPAWISGVPHSTAANERHHDYLTESTALIAGRVSALGDRTAEMRPEWSRTLGEAPTDPTQRARWQQQLAFVAAYRDQYRVTDDTAAQPAGPYIEEGRTGHHTYWTATEAAITARRIATTPNTPAPATADSDQQALRRLAADVYRTLPDADQTEILRTVAARTGATWLTGRPRLDDAALAQQHVAETVGAVLAERGQLTAEAARPEQRQTEEHHQPTLAERRRAGRQAERQAHRDQLQQGSGQPTRTARRASNRRVEPADQRQVQASAQRPAEQRQPLQLRPQQVQQDQPGPHLR
>NZ_CP025394|1353930:1416764|1382721_1383207_-|WP_104815095.1|DBSCAN-SWA
MDAQARLLILIDAFGKAGVEGRMKLAKLDFLLRYPDRFTTLMELRAPGIAAGENPWLTGAIEQGMIRYRYGPWDPAYYGLLGALIGKGLITTQQQGSVAAYAVTPDGHQLAAALAATDSWEAVRERARLLRRYFNLTGTSLKDLIYETFPDIVNTSWGAHL
>NZ_CP025394|1353930:1416764|1359950_1360343_-|WP_104815082.1|DBSCAN-SWA
MARVKRAVNAHKKRRVILERASGYRGQRSRLYRKAKEQVTHSLVYNYNDRKKRKGDFRQLWIQRINAAARANGITYNRFVQGLKIANVEIDRKMLADLAVNDPATFASLVEVAQKALPADVNAPKAAVAA
>NZ_CP025394|1353930:1416764|1368958_1369930_+|WP_104820685.1|DBSCAN-SWA
MLLDSASLYFRAYFGVPESLRAPDGQPVNAVRGLLDFISRLVEDHRPEQLVACMDADWRPQWRVDLIPTYKTHRVAEAAVEGEEEIPDTLAPQVPVIEQVLDALGIARVGVPGYEADDVIGTLATKATGPVRIVTGDRETADYQPARVLIVTGDRDLFQLVDDARGVQVIYPVKGVGNAEVITEAALLDKYGVTGAEYADMAALRGDPSDGLPGVKGIGEKTATQLIREYGDLAGIRAAAADPASRLTPARRKNILEAAPYLDVAPTVVRVATNVPLPAFDPTLPREPLDPMALEELSARWGLGTSLTRLLDTLAHAGTGVAS
>NZ_CP025394|1353930:1416764|1412898_1413489_+|WP_104815116.1|DBSCAN-SWA
MSQVPTAHNHLLLADTPNAASWARRHTRDVLGRWQMPPDLIDTALLIVSELIGNAVQHPGDAKQPEWLTSAELAKVKVIGLDLQLRGQAVLVQVADHDKRPPVPQNVDTDAEGGRGLFLVEHMSSQWGYYHPPTGGKIVWAEVRPSSPRKPQPATAEPPPSNRAARSRPFKPMTNEQLPVSDPNLMGRVLVGLRRI
>NZ_CP025394|1353930:1416764|1408199_1408709_+|WP_104815111.1|DBSCAN-SWA
MTEETQGQVERTLVLLKPDAVARGLSGRVLQRFEDAALKIVGTKMKWMDAEFTRRHYADLEERLGSEVYNLTATFMQQGPVIALVLEGYDAIATVRKIVGSTYPDQAPAGTIRGDFSHMSRGASVAVGKAVANLIHASGNREEAAQEVDLWFAKDELFDYKTLAETYIY
>NZ_CP025394|1353930:1416764|1366265_1366811_-|WP_158702051.1|DBSCAN-SWA
MVRRPGGRVAVVTGAGSGLGRAVAERLAADGLRVVCAEADEPAGRAVARSVGGLFVHTDPRDADMVEALYDEAYETCGGVDLAVHPVAPGPASRAALPYLRRHGHGVIVNLTADPADRELSAELARSYGREGIRVYGLRPGAALEPAVAAVAFLAGPGSAFLAPTEFVADDASGKIIAGPL
>NZ_CP025394|1353930:1416764|1364995_1366165_-|WP_104815087.1|DBSCAN-SWA
MSEQIPAGWYPDPQDTDSSPRPERWWDGQGWTATTRPGPSIALEGEVLDGGPTVRYPELPEVLAMQPARKRSKLSRPVALAATVAALAGLVVGSGITFLAMDGRSDTKAAPRAAGKSGSHFGGGGGGYGNGNGNGGGHGNGGDSFPGFGNGGSGNGGGSGNGNGNGGGNGFGFGGGNGSGGGLGNGGGNGGGGGLGGGNGSGNGSGGGGSLGRGGGSSDGPAIDAINGISIPVPTGWTGGTTATGFAALSVGSYKCPGGGSGTCSLGGVTTQSLKGTDAKAAAQTDIAAAAKDSYGDIKGHQELKNQAVKVDGRDGYLIRWKVDAPQGNDGYVQTVVFPNANNTALVSIHLGFDIADKAPSVDQMDAIVTSITDYSGGPLGGADGTTKT
>NZ_CP025394|1353930:1416764|1380796_1382725_-|WP_104815094.1|DBSCAN-SWA
MRLRIEELTISGTTRTVHFTPGLNAITGAMSGGKTATISCLRALLGGDVNVVPELKGRTTAGTVLIGNRRFRIVRPLVTTDTAKIDVAEIGGAEQAWRLPAARLEPGYNLTFRDWYLQMLGLPKVLVPRAPTDETSPLVPVTINDYLMYCVLRQDQIDSSVFGTPDNYHKDIKRKFVFEIYYGIFSPKAIELREHLRKVSVELKTLTADAKMLERVLEASSFSSSAQLQVQQSQAIEQLARSREAEQTLNRTLDEPATVSLRAQIAASEVDLQEADTALHSETATVARLVGLRDQLVAQSRRITRALVAERLLSDFEFHTCPRCGSDVPERGGEDTCRLCLQNPPAVIPTTALVSEQDRVIEQVAETDQLIARSRERLLLLQQTREAKAALRAELGAQLDRLTQGFLTDQVDRIRRFGADQARLEEQLLRIGEALALHQRLQNQGSRVAELEREREDLIGRLDAARHRNPVAEGRMADLDRAFENTLLSFDAPRVEPRPGSYISRKNYLPIVDGRSFSELSSQGVEVMVNVAHALAHQLVALAHPESILPNLLIIDGVSSNVGHEGIDLTRLKKMYATLLAAAQQSGEDLQIVVVDNDPPPIPGVHVALTLSDTDRLGHVSGCDHFVGFALALVPDPVDRVV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_104815079.1|1353930_1356444_-|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_104815080.1|1356443_1357565_-|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	5.6e-26	34.4
WP_104815081.1|1358926_1359787_-	RNA methyltransferase	NA	NA	NA	NA
WP_104815082.1|1359950_1360343_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_104815083.1|1360452_1360647_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_104815084.1|1360787_1361549_-	translation initiation factor IF-3	NA	NA	NA	NA
WP_174805505.1|1361994_1362372_+	DUF1844 domain-containing protein	NA	NA	NA	NA
WP_104815085.1|1362488_1363202_-	SseB family protein	NA	NA	NA	NA
WP_104820684.1|1363303_1364497_+	amino acid deaminase/aldolase	NA	NA	NA	NA
WP_104815086.1|1364564_1364939_+	hypothetical protein	NA	NA	NA	NA
WP_104815087.1|1364995_1366165_-	DUF2510 domain-containing protein	NA	NA	NA	NA
WP_158702051.1|1366265_1366811_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_104815089.1|1366945_1367743_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_104815090.1|1367768_1368869_+	cation transporter	NA	NA	NA	NA
WP_104820685.1|1368958_1369930_+	5'-3' exonuclease	F8WQ40	Bacillus_phage	1.2e-16	27.4
WP_104820582.1|1370246_1371038_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_104814471.1|1370994_1371540_-	hypothetical protein	NA	NA	NA	NA
WP_104815091.1|1371683_1376795_+	ATP-binding protein	NA	NA	NA	NA
WP_158702598.1|1378404_1378572_-	hypothetical protein	NA	NA	NA	NA
WP_158702052.1|1378568_1379300_-|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.2e-18	31.1
WP_104815093.1|1379403_1379577_-|transposase	transposase	NA	NA	NA	NA
WP_104815094.1|1380796_1382725_-	hypothetical protein	NA	NA	NA	NA
WP_104815095.1|1382721_1383207_-	hypothetical protein	NA	NA	NA	NA
WP_104815096.1|1383241_1384420_-	DUF4297 domain-containing protein	NA	NA	NA	NA
WP_168219558.1|1384455_1384761_-	hypothetical protein	NA	NA	NA	NA
WP_104815097.1|1385045_1388096_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_104815098.1|1388092_1389445_+	hypothetical protein	NA	NA	NA	NA
WP_104815099.1|1389441_1390941_+	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_158702053.1|1390975_1392616_+	ATP-binding protein	NA	NA	NA	NA
WP_104820686.1|1392873_1393746_+	HNH endonuclease	NA	NA	NA	NA
WP_168219559.1|1393905_1394091_-	hypothetical protein	NA	NA	NA	NA
WP_104820687.1|1394163_1395315_+|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	9.2e-32	32.7
WP_158702054.1|1395319_1396297_+|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.4e-68	51.3
WP_104815103.1|1396520_1397360_+	hypothetical protein	NA	NA	NA	NA
WP_158702055.1|1397473_1397914_-	DUF2335 domain-containing protein	A0A0D4DCC1	Staphylococcus_phage	7.4e-06	29.4
WP_104815105.1|1398465_1403490_-	relaxase domain-containing protein	NA	NA	NA	NA
WP_158702056.1|1403934_1404690_+	hypothetical protein	A0A2K9VI72	Mycobacterium_phage	4.4e-06	26.0
WP_104815107.1|1404788_1405193_-	NUDIX hydrolase	NA	NA	NA	NA
WP_104815108.1|1405185_1405836_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_104815109.1|1405873_1406416_-	flavoprotein	NA	NA	NA	NA
WP_104815110.1|1406412_1407693_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_104815111.1|1408199_1408709_+	nucleoside-diphosphate kinase	A0A167REB2	Powai_lake_megavirus	3.7e-17	37.7
WP_104815112.1|1408796_1409096_+	hypothetical protein	NA	NA	NA	NA
WP_104815113.1|1409247_1409829_+	hypothetical protein	NA	NA	NA	NA
WP_104820688.1|1409870_1410632_+	hypothetical protein	NA	NA	NA	NA
WP_104815114.1|1410634_1412017_+	hypothetical protein	NA	NA	NA	NA
WP_104815115.1|1412089_1412830_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_104815116.1|1412898_1413489_+	ATP-binding protein	NA	NA	NA	NA
WP_104815117.1|1413710_1415309_-	recombinase family protein	A0A222YXW7	Mycobacterium_phage	2.4e-107	44.4
WP_174805624.1|1416500_1416764_-|transposase	transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP025394|3814792:3823699|DBSCAN-SWA
TATGACTTCAACGACCGTTGCGGATGTGCGGGCCGCCGATCCCGCCAACCCGTACGCCGGACTCCGGGGCGGAAGCTACGCCCGCAAGAGCGCCTACCAGGGGAAGAAGGCGCGTAAGGGCGAGTCCGTGCGCGAGCAGCTCGACGCGAACAACCTTGACGCCGGGAGGCTCGGCGTCAACGTGGTCGAGGAGTTCATCGACGACGACCGCTCGGCATCCCGGCACGGCGCCAACGCCGAGCGCGAAGACTTCGAGCGCATGATCGAGTGGATCGAGACCGGACGGCTCGACATCGCGTTCGCTTGGGCATCGACTCGCTTGCAGCGCGACCTCGCGGTGTACGTGCGACTCCGTGACGCCTGCGCCAAGCACGGTGTGCTCTGGTGCGTCGGTGGCAAGGTCTACGACCTGACCAACAAAGACGACCGGTTCCGGACGGCGATCGACGCGGTGATCGGCGAGCGGGAGGTCGACGAGCTTCGGGCGAACGTCATGCGGTCGCTTCGGGCGAACGCGGTGGCCGGCAAGCCGCACGGCAAGAGGACCTACGGATACCGCCGCGTCTACGACGAGCACACCGGTGCCTTCCTGCGCGTCGAGAAGGAGCCGGCCGAGGCCAAGATCGTTAAGGAGATCAGCGAGCGAGTGGCGGGGGGCGAGGCGTACCTGCGGATCGCCCGCGACCTCGACCGTCGCGGAGTCCAGCCGCCGGCGCCCGAATGGACCTGGCAGCAGGTCAAGCGGCTCGCCGAGTGGCACGAGGGCTTGCCGAAGAACAAGGAACTCGCGCCGGCCACGATCCAGCGGATCAAGGATCATGCCGACCTACAGGCGGAGGCGCAGGAGCGGCTCGCCGCTGGCGAGGAGGCGCTCGACATCTCCCGCGACTTCAACGCTCGCGGGGTGCCGATCATCATGTGCCGGTGGCAGCCGCCGACCATCGTCGAGTTCGCCCAGCACACCCGGTACCTCGGCGTGCGGACCCACCACGGCGAGGTGACCGCCGAGGAGGCGTGGCCGGCGGTCGTGGACAAGGCGACCCATGCGCGGTGCGTGATGACCATCAAGTCACGCAAGGGCAAGCGGCGTTGGAACACCCGGCCCGGCGCGACCAAGCGTTGGCTGTCGGGCTCGATGATGTGCGATGTGTGCAGTCAGCCTGTCGGCTCGGACCTCAAGGACACCGGGCCTAGGTATGGCTGCGTCCAACCTGGGCAAGGCGACGAGAAGGGGTACCACGTCAGCGCGAAGACCGAGGATGTCGACCCGTTCGTATTGGGCAAGTTGCTGGACTGGCTCGCCAATCCGGCGTTCATCGCGGCGTTCACGCAGGGCGACGGGGAACTCGTCAAGCAGATCGAGGAGGCCGAGGCCGAGGCCGCGTTGCTGTCGGCGCAGCTCGACGAATTCATCGCCGAGGCGGGGGCCGGCCGCCTGTCCGCGCGCGCCCTGGTGGCCGTCGAGGCCGACTATCTGCCCAAGATCGAGGAGGCCAAGCGGAAGGCGCAGGCGCTGCGGGCGCCGTCCGTGGTCCGCGACTTCGCTGGCGCGACCCGTGAGGATCTCGAAAAGGCTTGGCCTGCGCTCAAGTTGGAGCAGCAGCGGTTGATCGCCGCGACGTTGCTCGACGTTCGCCTCAAGCCGCGCGGCAACAGCGGCAAGCGCCTTGAGGTGCACGAGTACGTGAGCGTCGAACCGCGTCGCATGCAGCTCGCCGCGTAGGCGGAAGCCGAAAGGGCCGGACAGCGTCTGCTGTCCGGCCCTTTCGCTATGCGTGGACGCCTCACGAGTCGCCGCCCCCGCCCGGTCCTGGGCAGCCGTCTGCCAGCCCGTTGAGCGCCGTCTCGATCGCGGCGGCGCCGGTCGCCGTGATGTGCCGGTCGTCGACCGTGAGCACGAGGTTCTCGTCGGTGGCTCTGACGACGGCCGGGGCTCCGGAGTCCAGTCGGGTACGGCGGACCTTGATCATTCGGTGTACTTCCCCCTTTGGAGCATGGCGCAGACTCGATTCGTACACAGTTTCGAACCGAGCTTCGTCACAGTACCTCCCGGACCGGCGCAGGTCACCCGCGTTCTGGTCAAGTTTTCAACTGGACGAACCTCCAGAGCCGGCCGCCCAGTTGCGCAGCAGTTCCTCGACCTTCGGCATGTCCGCCGGGCGCAGTCCGGGAACATGGGCGACGACGACAGCGGCCCCGGGGGTGGTTGCATCGAAGGGGTCGCCGGCCGTCAGGCCGATGTACTGCTCGGCGGCGGCGGCCTGTACCTCGCGGACATCCTTACCGAGGGCGGCGGCGACGGCCCGCACGATCCATGGCGAGATCTTGACCTGCTCGGCATGGGCAATCTTCCAGAGCGCGTTGTGCGTGAGCTGCTGGCCCGTCTTGGGGTCGATCGCCGTCTCTGCGAGCTTGCGGTAGGTCACCTCTTCGCCCGTGGTCGCTTCGCGCACCATCTCGGCGAACGGGGTGGATTCCCACATCGTTTCTCATCTCCGTTCGTGTCGCGTTACGCGAACAGCTCTATTGAAGCGCACATGCCGCTGGTTCAACCACTTGGGATATGCGTTGACGCGCACTATCGGCCGTCCTAGCGTGGATCTTGTCTCGAAACGAAGACAGACGGGGGGCCCTGAGCTGCACGTTCACACCTCCTGCATGTCTTCGTTCTGCAACAAAGACGCGAGGGGGAGCCGATGAACACCGATGATCACGCCGCCCGACCTGCGGGAACGCAGACGTGGCCGGATCCGAGCGACGCGCAGGTGTCGCTCGTCGCACGCATCCTCGGACCCCACATCCGGAAGGCGCGGGCCGAGCGCCTGGCCGCCGAGCAGGCCGCCGCCGGCCGCCCGGCCGTTGAGCGGGTCGCGGCATGAGCGCCGCTCAGCAGGTCGTCGAGTTCCTCGGCCCGCCGCCGGTCGCCGAGACCAAGCACACCCGGATCGCTCGGGCCCTGCGGGGCCGGCCGTCCGAGTGGGCGGTCGTCCAGCGGGCCGCGAGCATCGGCCGGGCCGCGTCGGCGGCGCAGGCGATCCGCTCGGCGCGGCTGCACGCCTACGAGCCGGCGGGTGCCTTTCAGGCTGTCGCGCGGACCGTGCAGGGCGAGCACCGGGTCTACGCCCGGTACGTCGGCGAGCAGGCGCAGGCCGTGGCCGACGGGGGTGTCGCCGCGTGATCCGCGCCCACCTTCACCCCGACCGGCACACCGTCCGGCTCGACGCCACCGACGCGGCCGAGCGGCTGCTCGACACCGTCGCGTTGGCGTTCGCCGCCGACGAGCAGGGCGTCGCCGATCTGCTGCGCGAGCTGGCCGAGGCCGCCGACCACCACCGTGCCCGCCGGGGCGACCCGCGGGCGACGGAGCACGGCCGGGAGTCGGCCGCCGCCGCGCTCGACGCCTACCGCGACGACACCCGCCAGGGGATCCGGCACACGGTCGAGCGCCGCCGCGCCGACCTGCTCGACACCCTGCCGGCGACCTGCGGCCTGCTCGCCGCCGATCTCACCTGGCGCACGTCCCTCGCGCTCGCCGACCAGCTGCGCGCCCTCGCGGCGCAGACGGTCGCCGGGAGCCGCGCAATCGAACTGGAGTCCGAAGCATGAGCGCGACCGACCAGCCCGACCCGTCGGCGGCGCGGCCCGGCGAGCTGTTCATCGGCGCCGCCACCGTGGCCACCACGGCCGAGGAGGTACGGCAGGTGTGGCGGCAGGCGCACGCCGCCGGCCAGCCGCAGTGGTACCTCGACCTCGTCGCCGGGATCGGCCGCACCAAACCGGGCGCCCGCACGGCCGACACCATGGCGGGTGCGGCGTGACGCGCCCCCGGGTGTGCGGCCTCGACCTGTCCCTGACCGCCTCCGGCGTGGCCGGGGCCAACTGGGCCCGCACGGTGGCCAGCAGCGGACACCGCGACGACTCGTTCCTCGCGCGCGGCACCCGGCTGCACCGCCTCGCCGGCGGCGTGGTCGCCCTGGTCGGCCGTTGCGACCTGGCCGTCGTCGAGGGCCCGGCCTACAGCCGCACCACCGGATCGGTCTGGGACCGCGCCGGGTTGTGGTGGCTGGTGGTCGACGCCCTGATGAGCCGTGGGATCCCGGTCGCGGTGGTCGCGCCGACCGCGCGGGCGAAGTACGCCACCGGCCGCGGCAACGCGTCGAAAGCGGCGGTGGTCGCCGCCGTGCGCCGTACCTACCGGGTGCCGGTCGCCGACGACAACCAGGCCGACGCGTTCACGCTCGCCGCGATGGGGCTCGACTGGCTCGGCGAGGCGCTGGTCGAGGTGCCCGCCGGTCAGCGGTGCGCGCTCGACCACGTCGCCTGGCCCGCCACGGCCGGCCCCGCGCAGCTCGCCCTCGACGGCGGCGCCGTGCCCTACCTCGACACCGTCGAGCCGGTGCGCCGCCCGCGCCGCCCGGCGCCCGTCGCCGTGCCCGACCTCGGCCCGTGCCCCGGTCAGCTCGATGCCCTGGCGGTGGTCGAGTGAGCGGCGATCTTCGGATCGGGTCGCTGTGCAGCGGCTACGGCGGGCTCGACATGGGCGTGCAGCGGGTGCTCGGCGGCTCGGTGGCCTGGCACTCGGACATCGACCCCGGGGCGCAGCGCATCCTCGCCCACCACTGGCCCGACACCCCCAACATCGGCGACCTGACGGCCGTCGACTGGGCGGCGGTCGAGCCGATCGACCTTCTCACGGGTGGCTATCCCTGCCAGCCGTTCAGCACGGCGGGACGCCGGAGAGGAACCACGGATGACCGGCACATCTGGCCGTACATCGCCCACGCCCTTGGGGTACTACGACCCCGATTCGCACTGTTTGAGAACGTGGGCGGACACCTTTCCCTGGGATTCGACACCGTCCTCGCCGACCTTGCCCGCCTCGGGTGGGATGCGGAGTGGGTGTGTGTACGCGCGTCCGATGTCGGCGCGGCCCACCAGCGCCGCCGGCTGTTCATCCTGGCGTGGCCTGCTGCCGACGCCGACGGCGACGTTCGTGCAGGACGTGATCACGCCCGAGCGGTGGCTCGCCCGGCGGGCCAGGATGCGTGCGCGGCACGGGGGTTCGAGCGACATGGGGTTGCCGCTCGGTCTGGCGGTGCGGCTGCTGCCGACGCCCACGGCGACGGAGGCGAGCGGGCCCGGACACACGTCGCAGGGCGGCCTCAACCTGCGGACCATGGTCAGCCTGCTACCGACCCCGAGGGCCAGCGACGGGAGCAAGGGGAGCCCGAACCAGCACGGCAGCAAGGGGGATCTGACTCTCGCGTCGGCGGCGTACCGGATTGGGGCGCCTACAGCGCGGCGGTCGCGGCGTGGGAGAGCCTCACACGTCCCGCACCCCGACCAACTGACGATCGAGGACGCCTGAGCCCGGCGTTCGTCGAGTGGCTCATGGGTCTTCCCGAGCACCACGTGACCGGTGTTCCCGATCTCAGCCGGGCCGCCCAGTTGCACGCGCTCGGCAACGGCGTGGTTCCCCAACAGGCCGCCCACGCACTGCGGTTGCTGCTCGACCGCGCTGCGCCCGCGCTCCCGCCCGGCTGACCGGGCCGATGCCCAGCACTCTCCTGATTCTCTCAACTTCCGCTAGGAGCACGACAGATGAGCCACTCGGCCCGCGATTGGGTCTGGGAGCGGTCTCGCACGCGCGGCACCGCCCGGCTGGTGCTGCTCTCGCTGGCCGACCACGTCACCGGCCCCGAGTGCCTGGCCTACGGCAGCACCCGTTCGCTGGCCGGGCGCACCGGGGCGGGCGAGCGCACCGTCGTGACGGCCGTCGACCGGGCCGTCGCGCTCGGCGAGCTTGAGGTCGTCGCGGGGCGGCGCGGGCCGCGCGGCGAACGCGTCTACCGCCTGCCGCACGCGGTCGGTTGGGTGCCCGGCGCCGCCGGCCAGGCCGAGCCCGACAGCCCCGAGCAGCCCGGTGAGGGGTGCGGAAACGGCACCGGTGGGGGTGCGGAAACGGCAGGGCAGGGGTGCGAAAACGGCATGAGCGGGGGTGCCGAAACTGCACCCGGCGCGAGCGGCGCGTGCAAAAGCTGCACCCCCGGGGGTGCAGAAACGGCAGGTCGGGGGTGCGAAAACTGCATGGGTGGGGGTGCAGTTTCAGCACCCCAGAACCTGAGTGAACAGAAAGGAACGGTAGAGGAACAGGAGCAGCGCGCGGGCGCGCGCGAAGCCTCCGCCTCCGCTGCTGCCCGCTTCGCTCTGCCCGTCGGCTGGGAGCCCGACGACGCGCTGATCGGCTGGGCCGCCGTGACCGGCCACCTGCAACGCCTCGGCGTCGAGGGCATCGACCGGGCCACCGCCAAGTGGCTGACCCACCGGGCCGCCGCTCCGGCCCGGACGGCCGAGCAGTGGCGGGCCGACTGGCGGCAGTGGATCGCCCGTGAGCGCACCGGCCCACAGCTTCGGGCCGTGCCCGACGGCGCGAGCACCGGCACCGGCACCCGGGCCGGGCGCAACGCCCAGCTGTTGCAGGCCGCACTCGCCGAACTCAACGCCCAAGGGGGGCAAGCCTGATGACTCCGAACGAGGTCGCCGCACTGCTGGCCTACGTCGCCGAGCTGGACCCGCGCACCGCCAACAGCAACCAGGACGAAGCCGCCGAGCAACTGCGCCGGTGGGTCGACCTGTTGCGCGATGTCCCGGCCACAGCGCCGGACGGCTGGGACGCCGCCGCCGTGGTGCGCCGGCACGTGACCGAGTCGCCGTACCGGATCCTGGCCGTCGATGTCACCCGCCCGTGGGCCGCGCACCGCCGCTCGCTGCTGGCCCGGCACACCGACCCGACCCCGCCGGTGGACCCCGACGACGTGGCCGCCTGGCAGGCCGCGATCCGGGCGCAGCGCGACGCGGTCGCCACCGGCCGGGCCGCGCCGAGCGCCTCCCGCGAACTGACCAGCGGCGCCCCGCACCCGGCCGTCGCCGCCCGGATCGCCTCGGCGGGCAGCCCGCTCCCGGCCGGGGCCGCCGAGGCGCTGCGGCCCTACCGCCCGGCGAAGGTCGCCCGGGAGACCGCCGCCGTCGAGGGCCGGGGCGACGAGCTGTCCGTCGCCTGCCCCTGGTGCCGCGCCCCGGTCGGCGAGCAGTGCCGGCGCCGCACCAACCGCGGACCCGACCGCGCTGGCACCTGGCACCGCCGAGCCACCGTCCACCCCAGCCGCCGAGACGCCGTCCGGCCCACCCGCAAGGAGAGTGCCGCATGACCCGCCACCGTCGCCGCGCCCGCACCAACAGCACCCACAACCAGACCGCCTACCGGCTCACCGCCGCGTGGCCGTCCACCACCCGGCCGACCCTGTTCCAGACCACCGACCGGCGCCGCCTCGACAAGGTCGCCCGCCAGCTCGCCGGAGCCGGCGCCACGGTCGACATCGAGGAGCACACCGGCCACGGCGCGTGGACCGCGCTCCGCCGGTTGGAGCCGACCCGGGCGCAGCGCCCGCGCACCACGGCCACCCGGCCGCACGCCGGCAGCGCCGAGGAGCACCTCGACGGGGTCGAGCGACTGATGAGCCGCCCGCCGATCCCGCGCGACGGCGGCAAGCCGACCGCGCGCACCGTCGCCCACGGCCGGGGGATCCGATGAGCGCCCCGGACCGCGCCGATGTCACCGTGCTGCTGCACCTGGTCGAGCGGGCCGAGCGCGGCGCCCTGCTGCCGGGTGAGGCCGTGATCCTGCGCGAGGGGATCCGCGACCTGGCCGTCTACCGGGAGTGGTGCGGCGAGTGGAGCCGGATCGTGGACGACGGCCGACGCTACTTGCACGTGATGCGCCGGGCGCTTCGCCGCGCGGTCGCCAGGGCGCAGCGCGGCCGGCAGGCCGAACTCGAGGTCGCCCGACTGCGCGCCGCCACCGCCAACACGGCCGAGCCGGACGGGCAGGCGTACGAGGCGTTGCTCGCGGCCCAGTTGCTCGACGGTTTCGCGCTCGCCCGCGCCGCCCGCCGCCTCGAACCCGTCACGCGACGGTCGGCGGCCCCCTGACCGGCCTGGGCGCCCCCGTAGGCCGCAGAGGGGCGCCCAGGCTCACCAACCCGTTCCACCCGCACCAGACCGGAGAGAGCGCACCGTGTACCAGCCCGCCGACATCCACCGAGCCGCCGATCAGCTGCGCACCGTCCGCACCGAGTGGGCCGCGCTGTTGATCGCCGTTGAGACCCCGCCCGCCGCTGCCTGGCCGCCGGCGCAGCTCTCCACCCACCTCGCCCAGCAGCAGGCCGCCGAGGCCGACCTGCTCGTCGCCGACCGGGCCCCGCTGACGCTGCGCCAGCACCCGGCGCCGGCCAACCTGACCGCGCTCGACGCCGCCGTGCGCGTCGAGGGGCTGCTGTTCGACCTGGCCGACACCCTCGCCGCCGCCGCGCAGCGCCCGATCGGCCGCCGCCTGGTGTCGAGTGTCGGGCGGCCGGAGGTGTGGGCCGACGACGAGGCCGACGCCGCCGACCCTCGCCGCTGGCGCTTCCGCAGCCCGACCGACCCGGGATCCCGCCGCCACGGTCTGCACTTCGCCGCCCTGTGGGTCGAGGGCCGTCTCCTTGATGAGGACACCGAGCCCGAGCGGCACCTCGACGGCAGCGAAGCACCGGCCTTGTTCGCGCGGCTGCCCGAGCACCTGCGGCACGAGACGATCCGCGTCGCGCGGCAGTGCGAGCGCCTGGTGCTGCGGGTGCTGGAGTTGGACGAGCGCGAGACCCCGGTCGAGGGGCGGCCGTGCCCGTGGTGCGGCGGTGCACTGACCCTGCACACCGCCGCCGACCAGGCGCCCCGGGTCACCTGCGACGGTGGCAGCGGCTGCTCGGCCGCGGTACCGCTGGACAACCGCGGACGCCGGGTCTGGGGCGCGGTCGACCTGCTCACGCTGATCGAAGCTCTCAACGAAGCGGTGGCCGTCCGGGCCGCCTGA

Protein sequences of DBSCAN-SWA_3

>NZ_CP025394|3814792:3823699|3816878_3817274_-|WP_104816828.1|DBSCAN-SWA
MWESTPFAEMVREATTGEEVTYRKLAETAIDPKTGQQLTHNALWKIAHAEQVKISPWIVRAVAAALGKDVREVQAAAAEQYIGLTAGDPFDATTPGAAVVVAHVPGLRPADMPKVEELLRNWAAGSGGSSS
>NZ_CP025394|3814792:3823699|3817965_3818397_+|WP_104816830.1|DBSCAN-SWA
MIRAHLHPDRHTVRLDATDAAERLLDTVALAFAADEQGVADLLRELAEAADHHRARRGDPRATEHGRESAAAALDAYRDDTRQGIRHTVERRRADLLDTLPATCGLLAADLTWRTSLALADQLRALAAQTVAGSRAIELESEA
>NZ_CP025394|3814792:3823699|3818605_3819277_+|WP_158702206.1|DBSCAN-SWA
MTRPRVCGLDLSLTASGVAGANWARTVASSGHRDDSFLARGTRLHRLAGGVVALVGRCDLAVVEGPAYSRTTGSVWDRAGLWWLVVDALMSRGIPVAVVAPTARAKYATGRGNASKAAVVAAVRRTYRVPVADDNQADAFTLAAMGLDWLGEALVEVPAGQRCALDHVAWPATAGPAQLALDGGAVPYLDTVEPVRRPRRPAPVAVPDLGPCPGQLDALAVVE
>NZ_CP025394|3814792:3823699|3822378_3822780_+|WP_104816837.1|DBSCAN-SWA
MSAPDRADVTVLLHLVERAERGALLPGEAVILREGIRDLAVYREWCGEWSRIVDDGRRYLHVMRRALRRAVARAQRGRQAELEVARLRAATANTAEPDGQAYEALLAAQLLDGFALARAARRLEPVTRRSAAP
>NZ_CP025394|3814792:3823699|3814792_3816514_+|WP_104816826.1|DBSCAN-SWA
MTSTTVADVRAADPANPYAGLRGGSYARKSAYQGKKARKGESVREQLDANNLDAGRLGVNVVEEFIDDDRSASRHGANAEREDFERMIEWIETGRLDIAFAWASTRLQRDLAVYVRLRDACAKHGVLWCVGGKVYDLTNKDDRFRTAIDAVIGEREVDELRANVMRSLRANAVAGKPHGKRTYGYRRVYDEHTGAFLRVEKEPAEAKIVKEISERVAGGEAYLRIARDLDRRGVQPPAPEWTWQQVKRLAEWHEGLPKNKELAPATIQRIKDHADLQAEAQERLAAGEEALDISRDFNARGVPIIMCRWQPPTIVEFAQHTRYLGVRTHHGEVTAEEAWPAVVDKATHARCVMTIKSRKGKRRWNTRPGATKRWLSGSMMCDVCSQPVGSDLKDTGPRYGCVQPGQGDEKGYHVSAKTEDVDPFVLGKLLDWLANPAFIAAFTQGDGELVKQIEEAEAEAALLSAQLDEFIAEAGAGRLSARALVAVEADYLPKIEEAKRKAQALRAPSVVRDFAGATREDLEKAWPALKLEQQRLIAATLLDVRLKPRGNSGKRLEVHEYVSVEPRRMQLAA
>NZ_CP025394|3814792:3823699|3819273_3820335_+|WP_104816833.1|DBSCAN-SWA
MSGDLRIGSLCSGYGGLDMGVQRVLGGSVAWHSDIDPGAQRILAHHWPDTPNIGDLTAVDWAAVEPIDLLTGGYPCQPFSTAGRRRGTTDDRHIWPYIAHALGVLRPRFALFENVGGHLSLGFDTVLADLARLGWDAEWVCVRASDVGAAHQRRRLFILAWPAADADGDVRAGRDHARAVARPAGQDACAARGFERHGVAARSGGAAAADAHGDGGERARTHVAGRPQPADHGQPATDPEGQRREQGEPEPARQQGGSDSRVGGVPDWGAYSAAVAAWESLTRPAPRPTDDRGRLSPAFVEWLMGLPEHHVTGVPDLSRAAQLHALGNGVVPQQAAHALRLLLDRAAPALPPG
>NZ_CP025394|3814792:3823699|3816575_3816761_-|WP_104816827.1|DBSCAN-SWA
MIKVRRTRLDSGAPAVVRATDENLVLTVDDRHITATGAAAIETALNGLADGCPGPGGGGDS
>NZ_CP025394|3814792:3823699|3821995_3822382_+|WP_104816836.1|DBSCAN-SWA
MTRHRRRARTNSTHNQTAYRLTAAWPSTTRPTLFQTTDRRRLDKVARQLAGAGATVDIEEHTGHGAWTALRRLEPTRAQRPRTTATRPHAGSAEEHLDGVERLMSRPPIPRDGGKPTARTVAHGRGIR
>NZ_CP025394|3814792:3823699|3820392_3821313_+|WP_104816834.1|DBSCAN-SWA
MSHSARDWVWERSRTRGTARLVLLSLADHVTGPECLAYGSTRSLAGRTGAGERTVVTAVDRAVALGELEVVAGRRGPRGERVYRLPHAVGWVPGAAGQAEPDSPEQPGEGCGNGTGGGAETAGQGCENGMSGGAETAPGASGACKSCTPGGAETAGRGCENCMGGGAVSAPQNLSEQKGTVEEQEQRAGAREASASAAARFALPVGWEPDDALIGWAAVTGHLQRLGVEGIDRATAKWLTHRAAAPARTAEQWRADWRQWIARERTGPQLRAVPDGASTGTGTRAGRNAQLLQAALAELNAQGGQA
>NZ_CP025394|3814792:3823699|3817487_3817670_+|WP_158702205.1|DBSCAN-SWA
MNTDDHAARPAGTQTWPDPSDAQVSLVARILGPHIRKARAERLAAEQAAAGRPAVERVAA
>NZ_CP025394|3814792:3823699|3817666_3817969_+|WP_104816829.1|DBSCAN-SWA
MSAAQQVVEFLGPPPVAETKHTRIARALRGRPSEWAVVQRAASIGRAASAAQAIRSARLHAYEPAGAFQAVARTVQGEHRVYARYVGEQAQAVADGGVAA
>NZ_CP025394|3814792:3823699|3822865_3823699_+|WP_104816838.1|DBSCAN-SWA
MYQPADIHRAADQLRTVRTEWAALLIAVETPPAAAWPPAQLSTHLAQQQAAEADLLVADRAPLTLRQHPAPANLTALDAAVRVEGLLFDLADTLAAAAQRPIGRRLVSSVGRPEVWADDEADAADPRRWRFRSPTDPGSRRHGLHFAALWVEGRLLDEDTEPERHLDGSEAPALFARLPEHLRHETIRVARQCERLVLRVLELDERETPVEGRPCPWCGGALTLHTAADQAPRVTCDGGSGCSAAVPLDNRGRRVWGAVDLLTLIEALNEAVAVRAA
>NZ_CP025394|3814792:3823699|3821312_3821999_+|WP_104816835.1|DBSCAN-SWA
MTPNEVAALLAYVAELDPRTANSNQDEAAEQLRRWVDLLRDVPATAPDGWDAAAVVRRHVTESPYRILAVDVTRPWAAHRRSLLARHTDPTPPVDPDDVAAWQAAIRAQRDAVATGRAAPSASRELTSGAPHPAVAARIASAGSPLPAGAAEALRPYRPAKVARETAAVEGRGDELSVACPWCRAPVGEQCRRRTNRGPDRAGTWHRRATVHPSRRDAVRPTRKESAA
>NZ_CP025394|3814792:3823699|3818393_3818609_+|WP_104816831.1|DBSCAN-SWA
MSATDQPDPSAARPGELFIGAATVATTAEEVRQVWRQAHAAGQPQWYLDLVAGIGRTKPGARTADTMAGAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_104816826.1|3814792_3816514_+	recombinase family protein	A0A2P1N2W7	Gordonia_phage	6.6e-50	29.9
WP_104816827.1|3816575_3816761_-	hypothetical protein	NA	NA	NA	NA
WP_104816828.1|3816878_3817274_-	hypothetical protein	NA	NA	NA	NA
WP_158702205.1|3817487_3817670_+	hypothetical protein	NA	NA	NA	NA
WP_104816829.1|3817666_3817969_+	hypothetical protein	NA	NA	NA	NA
WP_104816830.1|3817965_3818397_+	hypothetical protein	NA	NA	NA	NA
WP_104816831.1|3818393_3818609_+	hypothetical protein	NA	NA	NA	NA
WP_158702206.1|3818605_3819277_+	hypothetical protein	A0A0F6YQQ7	Mycobacterium_phage	5.8e-18	39.1
WP_104816833.1|3819273_3820335_+	DNA cytosine methyltransferase	G1DUR4	Mycobacterium_phage	3.3e-68	46.6
WP_104816834.1|3820392_3821313_+	helix-turn-helix domain-containing protein	A0A1J0MCN2	Streptomyces_phage	9.0e-14	42.3
WP_104816835.1|3821312_3821999_+	hypothetical protein	A0A1J0MCX6	Streptomyces_phage	2.2e-28	37.9
WP_104816836.1|3821995_3822382_+	hypothetical protein	NA	NA	NA	NA
WP_104816837.1|3822378_3822780_+	hypothetical protein	NA	NA	NA	NA
WP_104816838.1|3822865_3823699_+	hypothetical protein	A0A1J0MCS6	Streptomyces_phage	2.6e-44	44.0

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP025394|8433009:8474425|DBSCAN-SWA
AATCCATGCCAGCACCCATGTGAAGCGGGCCTACCGCTATCGCTTCTATCCGACTGACGCGCAGGCAGCCGAGCTGTCGCGCACGTTCGGGTGCGTGCGGAAGGTCTACAACATGGCGTTGCAGGCGTGCACGAAGGCATGGGCGCTGAATCAGGAACGGGTCAGCTACGGCGCCACGTCGGCGATGCTGACGCAGTGGAAGAAGACCGAGGACCTGGCCTACCTGTCCGAGGTGTCCTCGGTCCCCTTGCAGCAGACGCTTAGGCACCTGCAAGGGGCGTTTACCAACTTCTGGCAGAAGAGGGCGAAGTACCCGAGATTCAAGTCCCGAAAGAAGTCCCGGAAGTCCGCGGAGTACACGAGGTCCGCGTTTCGGTTCCGGGACGGTCGGCTGTGGCTGGCGAAGATGGCCGGGCGCTGGTTCGTCTCCATGCTGTGCGACGACCGGCCGGCCATGCCGGTACCAGTCAGCGCGGCCGTGGGGATCGACGTGGGTATCATCAGCGTGGTGACGCTCTCCACGGGGGAGAAGATCACCAACCCCCGGCAGGAGAGCAAGGGGCGGGAACGCCTCGCCAAGGCCCAGCGTGACCTCGCCCGCAAGGCCGAGGGCGATGGCATGAACCGGGCGAAGGCCCGGCGCAGGGTTGCCCGAGTGCACGCGAGGGTCGCCGACCGGGGTAGGGATTTCCTGCACAAGCTCACCACTCGACTCGTTCGTGAGAACCAAACGATCGTGATCGAGGATCTGACCGTCCGGGACATACTCAAGAATCGGCGGCTCTCCCGAGTCGTCTCGGATGCCTCCTGGACCGAGATGCGTTCCATGCTGGAGTACAAGACGGATTGGTACGGGCGCGAGTTGATTGTGATCGATCGCTGGTTCCCCTCCTCCAAGCTGTGCTCCAGCTGTGGCACCTTGCAGGGCAGGATGCAGCTCGACGTCCGCGAGTGGACGTGCGGCTGCGGGGCGACCCACGACCGGGACGTGAACGCAGCGATCAACATCCTGGCCGCCGGGCTGGCGGTTGCAGCCTGTGGAGACGGTGTAAGACCTCAACGGAGCACTCCGGGCGGGCAGTCGTCTATGAAGCAGGAAGTTGTCCCACCGCCGCGCTCACGCGCAGCGGGTCAGTCGCGAGGCTGAGGGGAATCCCCGTTCTTCGGAGCGGGGAAGGAGGTCAATTCCGGTACAACCCGTCCTCGCCGAAGGCGTGGGCCAGCTTGTTGGCGCCCCAGATGAGCAGGAGGGAGACCACGCTCTTGAAGAGCCCGGCCGCCGCGCCGAAGCTGTAGCCGCCGGTGGCGATGCCGTAGTAGAAGGAGAAGGTGTCCAGGACGTCGGCGGCGTCGTGGCCGACGGCCTCGCGCTGGATCAGGAACTGCTCGAAGCCGACCGAGAGGGCGTTGCCCAGGCGCAGCACCAGCATCAGCACGATCACCCCGCGCAGGCCCGGCAGCGTGATGTGCCACAGCCGTCGCAGCCGCCCCGCGCCGTCGGCCGCCGCGGCCTCGTACAGCTCGCCGTTGATCGCGCTGAGCGCCGCGAGGAAGACGATGATCCCCCAGCCGGCCTCCTTCCAGATGGCCTGGGAGGTGACCAGGAGGGCGAAGGTGTGCGGGTTGGTCATGATGTCCCAGGTGGCCAGGGAGTGCTGGCGCAGGAACTGGTTGAGCGCGCCGGCGCCGCCGAGCATCTGCTGGAAGATGGTGACCGCCAGCACCCAGGAGAAGAAGTGCGGCAGGTAGACCACGGACTGGAAGAAGTTGCGGATCCGCTCGCTCACCACGGAGTCGAGCAGCAGGGCGAGCGCGATCGGGACGGGGAAGAAGAGCACCAGCTGGACGAAGCTGAGGTAGAGCGTGTTCTTCAGCGCGGCCCAGAACGCCGGGTCGTTGAAGAGCTGCTGGAACTGGTCGAGGCCGACCCACTCGCTGTGCCAGACCCCGACCAGCGGGTCGTAGTCCTGGAAGGCGGTGACGATGCCGAACAGCGGCGCGTAGTTGAAGACCAGCAGCAGGAGGACGGCGGGCACCGTCATCAGCAGGAGCGACCTGTCGCGCCGCAGCCTGGCCCGCCAGCCGAGCCGCGCGGGGTGGGCCGGGCGCTTCGGTGCGGCGGTGCTCACCGGCCGGCGCCGTACTTGTCGAGGACCTCGGTGGTCATCCACTGCTTGAGCCGCTCGCCGGGGCCGGAGCGCCAGGCGGCGATGGCGGCCTGCACGTCGGAGACCTTCTTCTTGCCGTGGTAGCAGTCCTTGAGGGTGTCGTTGACGCTCTGCGCGGCGTCGGCCACGGAGATCGCCTGGGGCATGCTGAAGTTCATGCCCCAGAAGGGCGGCTTGGTGAGGTACTTGACGTTGGCCGCGGACCAGGCCGCGTAGTCCTTGGTGACCTGGTCGCCGCCCGGGTTGCTGATCACCGAGGCGGGGGCCGCCAGGAACGGCAGGGCCGTCGCCTGGACGTCCTTCTTTCCCTCCTCGGTGAAGGTGGGCACGCCGTTCACCCGGGTGTGGTGGACGCCCTCGACGCCGAAGTTGACCAGGGTGTACTCGGCGGTGCCGTAGGGGGCGGCGAGGTAGTCGGCGACGCCGAGCAGCTCCTCGATCTGGGCGGGCTTCAGAGCGGCGTTCAGGTAGCTGATCATGCTGCTGGAGGCGCCCATGTAGATCACCGGGGTGCCCTTGCCGTCGGCGGTGAGGGCGTCGAGGGCGCCGCGCCGGTACTTCGGGTCGGCGGCGGTGCCGGACTGGTGGTCGGCCAGGTTCCAGGCGCCCAGTCCGCCGCCCCCGATGAGCGTCTTGCCGCTGTAGAAGCGGGTGTTCCCGTTGGCGTTGTCGCCGGCGAGCGCGTCCGGGTGCATGAAGCCGGAGGTGGCCAGGCGGTAGTGCCAGTCGAGGGCCTCCAGGAACTCCTGGGTCTCGAAGGGGTGGACCAGCTTGCCGCCCTCGATCCGCCAGTTCATGGGGACGTTCCAGGCCGTCTGGAGGTAGGTCCACACGTCGTCGAAGGCCCACACGCCCCGCTTGGCGTCGGTCAGTTCCTTGCCGAGGTGCATCAGGTCGTCGGCGGACCTGATCTGGTCGGGGGTGATGCCCCGGGCTTCGAGGACGTCCCGGCGGTAGAAGGTGGCGCCGGGGATGCCGAAGCTGGTGGAGAAGCAGGGGATGCCGTAGAGCCGGTCGCCCCAGACCCCGTCCTGCCAGGCGCCGGTGGGGAGGGCGGCCAGGTTCGGGTACTTCTTGATCCAGTCGCCGGACAGGTACGGCGTCAGGTCCGCGAGTTGGGCGCCGACCAGTGAGCCGGTGTTGAACTTGGCGTTCCACCAGGCCGGCAGGTTGATCCAGTCGGGCAGCTTCTTGGCGGCGGTCATGGTCGGCACGATGGTGTCGTAGGTGTTCCCGTCGGCCGGTTTGACGGTCAGTTCGATCCCGAGGGCCTTGTCCATCGCCTGGAAGAAGGAGTTGCCGGCCGGCGGGTTGGTGCCCCAGAGCGGGGTGACGGCGGTGTAGCTGCCGCCCTTGCCGGGGACGCCGCTCACGCTGGTGGGCGGGTGCGCCGGGTAGGACAGGTAGGCCGGGTCGGTCGCGGCGTCCGCTCCGCCCGCGACCGGGGCGATGTCGGGCTTGACCGCGCCGGCGTTCGCCAAGTAGGTCGGCAGGGCCGACTTGAGCCCTGCCGCGGTGTTCGCGGCGGCCTTCCTGCCGCCACCGTCGCCGCAGGCGGACAGCAGCGGCGCCATCGCGGCGGCCCCTGCCACGGTGGCGGCGGTGCTCAGGAAGCTCCTGCGGTTCATCCCGGATCTCATGGTGGCGTGGCCCCTCTCCGTCGAAGCGCGTCGATGCGCGCTGAGAGTGTCGAAGCGTGGCGAAGCGTCGAAACGCTTGGATGTTTCGGCGAGACTAACGACGCGTTACCAATTGGGCAAGGGCCTGAACAAATCCAAAATCCTTCTCTCCCTTGGGGGTTGACGCCCCCGTCGGAGCGTGCCAGCGTCGAAGGGCTTCGACGTGCGACCACCGAGCCGAGCCGCCCTAGGGGTATTCAAGTTGAGTTCTGTGCCCAGGTCCGACGCTGTCCTGCCCGAGTTCCGCAATCCCGCGCTGCCGCTGCGCAAGCGCATCGACGACCTGCTCGAGCGGCTGACGCCCGAGGAGCGGCTCGCGATGCTGCACCAGTACGCGCCCGCTGTCCCGCGCCTGGGAGTCGCCGCGTTCCGTACCGGCAGCGAGGCGCTGCACGGGGTGTCCTGGCTGGGTGAGGCGACGGTCTTCCCGCAGGCCGTCGGCCTCGGCGCCAGCTGGGACGAGAGCCTGGTGCGCGAGGTCGCGGCGGCGGTCTCGACCGAGCTGCGGGCCTTCCACCTCCACCGTCCGCCCGCGATCGGCGCCGCCGAGCGCGGCGCCACCTCGCTCCAGGCGTGGGCCCCCGTGCTCAACCTGCTGCGCGACCCGCGCTGGGGCCGCAACGAGGAGGGCTACTCGGAGGACCCGGTGCACACCGCCCGGATCGGCGAGGCGTACTGCCGGGGCCTGGCCGGCGACCACCCGGTCTACCTGCGCACCGCGCCGGTGCTCAAGCACTTCCTCGCCTACAACAACGAGGACGACCGCTGCACCACCTCCTCCGGGCTGCGCCCGCGGGTGCTCCAGGAGTACGACCTGGCCGCCTTCCGCCCGGTGGTCGCCGCCGGCGCGGCGACGGGCGCGATGGCCGCCTACAACCTGGTCAACGGCCGCCCCTGCCACGTCAGTCCGCTGATCGAGACGGAGCTGCGCCGCTGGGCCGCGCCCACCGGGCACGAGCTGTTCGTGGTCAGCGACGCCGAGGCCCCCTCCAACCTGGTCGACCCGGAGCACTACTTCGACGACCACGCCGAATCCCACGCGGCGGCGCTCAAGGCCGGCATCGACAGCTTCACCGACCACGGGGAGGACAGCGAGACCGTGGTCGGCCGGCTGCGCGAGGCCCTGGAGCGCGGCCTGATGGCGCAGCAGGACGTGGACCGCGCCGTCCGGCGGCAGCTCGAACTGCGCTTCCGCCTGGGCGAGTTCGACCCCGAGTTGGACCCGTACGCGGGCATCGGCCCCGAGGTGGTCGACTGCGCCGAGCACCGCGCGCTGGCCCGGAGGGCGGTGGCGGAGTCGACGGTACTGCTGAAGAACGAGGGCCTGCTGCCGCTGGATCCGGCCCGGCCGCCCCGGATCGCCGTGATCGGCCCGCTCGCCGACAGCGTGTTCGAGGACTGGTACAGCGGCACCCTGCCGTACCGGATCGGCCTCGCGGGCGCCCTGGCCGCCGCCGGCGTCGAGGTGACCCGGGTGGACGGCTCGGACCGGATCGCGCTGCGCTCGCGCACCACGGGTGAACTGCTCGGCAAGACCGCCTTCGACCTGACCGACTGGGGTGGCGGCGCCGTCACCCTGCGCGCCGCCGACACCGGCCGCTACCTCGGCCTGCAGGAGGACGGCGGGCTGGCCGCCGACCGGAGCGTGATCAAGAGCTGGTTCGTCACGGAGACCTTCCGGCTGGAGGCGGTGGGCCCGGACGAGGTGGTGCTGCGCAGCGTTTTCACCGGTCGGTACGCCGGGGTCGATCCGACGGACGGTCGTGTGAGCGTTCACATTGAAACGGCGGCCGAGGCCGAGCGGTGGCAGCGCGAGCTGGTGCGCGACGGCCTGGCCGAGGCCCGGGCCGCCGCCGAGGCGGCGGAGGTGGCGGTGGTGATGCTCGGCAACCATCCGATGATCAACGGCCGGGAGACCGAGGACCGCGCGGACATCGCCCTGCCCGAGGGGCAGGAGGCGCTGCTGCGCGCGGTGGCCGCCGCGCGGCCCGAGACGGCGCTGGTCGTGACGAGCAGCTACCCCTACGCCCTCGACTGGGCCGACGAGCACCTGCCCGCCGTGGTGTGGACCTCCCACGGCGGGCAGGAGGGCGGCCACGCGCTGGCCGATGTGCTGCTCGGTGCGGCCGAGCCGGCCGGCCGCCTGCCGCAGACCTGGTACCGGGGCGAGGACCCGCTGCCGCACCCGCTCGACTACGACGTGATCAAGGCGGGCTGGACCTACCAGTACCACCGCACCCCCGCCCGCTACGCGTTCGGCCACGGGCTCTCCTACACCGAGTTCGCCTACCGCGACCTGCGCCTGTCGCAGCCGTCGATCGATCAGGCCGGCGCGGTCGAGGCCGTCGTGACCCTGGAGAACACCGGCGAGCGGCCCGGCAGCGAGGTGGTCCAGGTCTACCTCCGGGCCCCGGAAGCCCGTTACGCGGCCCCCCGGCTCAGCCTGGCCGAGTTCCGCAAGCTACGGCTGGAGCCGGGGGAGAGCCGCGAGCTGACCTTCCGGCTGACGGCCGGGCAGCTCGCCCACTGGGACGTGGCCACCGGCGCCTTCACCGTCGATCCGGGCCGCTACGAGGTGATCGTCGCCCGCAGTGCCGACCACCACGAGCTGACCGCGCCGCTCACCGTGACCGGCGCCGCCCCCGCGCCCCGGGCGGGCGTCGGACGCTGTCTCCTGGCCGTGGACTTCGACGACTACGAGGAGGCCGTCATCGTCGACGCCACCCGCGCCGACGGCGACGCCGTCACGCCCGCCGACCCGGCCCGGCCGGCGACGCTCCTCTTCCGCGAGGTCGACCTCTCCGGGGCCGCCCGGGTGGAGGTCGAGACCGCCCGCGAGGGCGTCGGCCCGGGCGGAGCGCGGCTCGAACTCCGTTCGGGGGGAAGGCTGCTGGCCGCGATCGAGGTGCCGGTGACCGGCCACCGCTACGCCTGGACCACCACCGGCGCCAAGCTCGCCGCCCCCCTGGACGGCGTGCACGACCTGAGCCTGGCCCTGCACGGCGACTTCCGGCTGGCCGCCTTCCGCTTCGGCGCGGCCGGCTGAGACCCACCGCCCCACAGACCGGCGGCCCGCCCAAGGGGGGAGCGGGCCGCCTCCCCGCCCCCGGCCCGCGAGCCGGGCGCCCCCGCCTACCGCTGCATCCGTCCCGACCCCGTCACCCGCCGCCCGGAGGCGGCTCCCATGTCACTGCCCACGCCCCACCACCGCACCTCGTCCTCGCCACACCCGGAGGAGTCCGCCGTGCCGCCCACCGACCTCGGACTCGACGCACTCGCCGACCACAAGCCCGAGCCGGCCGCCCCGCAGGACTTCGACGCGTTCTGGCAGCGCACCCTCGCCGAGGCCCGCTCGCACGGCGGAGCGGTGAAGGTCGAACGGGTCACCGAGCGGTACGGCCTGCGTACCGTCGAGGTGGAGGACGTGCGCTTCCCCGGCTGGAACGGCGAGCCGGTGGCCGCCTGGCTGCTGCGCCCGCGCGGCGCCGAGGGGCCGCTGCGCGGCGTTGAGGGGCCGTTGCCGGTCGTCGTCACCTACCTCGGCTACAGCGGAGGCCGCGGGCTGCCCACCGAGCACCTGTTCTGGTCCGCCGCCGGCTATGCCCAACTCGTGGTGGACAGCCGGGGCCAGGGACACGACACCCCGGACCGGACCGTGGGAGACGGCACGCAGTGGGCCGAGGGCTTCATGACCCGCGGCATCGACTCGCCGGAGCACCACTACTACCGGCGGCTGATGACCGACTGCGTGCGCGCCGTGGACGCCGTCGGCCGGCTCCCCGGGCTGGACAGCGGCAAGGTGGTGGTGACCGGTGTCAGCCAGGGCGGCGGCCTGGCCCTCGCCGTCGCCGGACTCACCGGAGACGGGGTGGCCGCGGTGCTGCCGGACGTCCCGTTCCTCTGCCACTACCGCCAAGGCGCCCAGCTGTCCCTGGAAGGGCCGTACCAGGAGATCGTGAAGTACCTGCGCTGGCACAGCCGGCACCGGGTGGCGGAGACCTTCGCCACCCTGGGGTACTTCGACGGCGTCCACTTCGCCCGGCGGGCCACCGCACCCGCCCTGTTCAGCGTCGGCGGGATGGACCCGGTCTGCCCGCCCCCGACGGTGTACGCGGCGTTCAACCACTACCGGGGTGCGGACCGCACCATGACGGTCTGGCCGTTCGCCGACCACGCCGGCGGCTGCGGATCGAACCCGCCCGTCCAGCTGGCCTGGCTGCGCGAGCGCGGGCTGGGCCCGGCGTGAACGCTCCCGCTCAGCTGGTCCGGTGCCTGCCCGCCGGGTTCCGGTTCGGCGCCGCCACCGCCGCGTACCAGATCGAGGGCGCCCACCGCGAGGACGGCCGGGGCCCGTCCGTCTGGGACACCTTCAGCCACACCCCGGGCCGCACCCTCGACGGCGCCACCGGCGACACCGCCTGCGACCACTACCACCGCTACCCCGAGGACGTGGCCCTGCTGCGCGGGCTCGGGGTGGACGGCTACCGGTTCTCGATCTCCTGGCCGCGCCTGCTGCCGCAGGGCACCGGGCCGGTCAACGCCAAGGGGCTGGACTTCTACGACCGGCTGATCGACGAGCTGCTGGCCGCCGGCGTCGCGCCCGCCGTGACGCTGTACCACTGGGACCTGCCGCAGGCCCTCGAAGACCGGGGCGGCTGGCGGGTGCGCGCCACCGCCGAGGCGTTCGCGGCGTTCGCGGCGCTGGCCGCCGAGCGGTACGGGGACCGGGTCGAGCGGTGGATCACCCTCAACGAGCCGTACTGCTCCGCCTTCGTCGGCTACGCCGAGGGACGACACGCACCCGGGGCCCGGGAGGGCCGGGGCGCGCTGGCGGCGGCCCACCACCTGCTGGTCGGGCACGGCCTGGCGGTGCGCGAGCTCCGGGCGGCGGGGGCCCGGGAGATCGGCATCACCCTCAACCTCGACCGGGTGCACGCCGCCTCCACGCTCCCCGAGGACCTCGCCGCCCGGCGCCGCGCCAAGGTGCTGCACAACGAGGTCTGGACCGAGCCGCTGTTCGCCGGGCGCTACCCGCCCCAGGAGCGGCAGACCTGGGGCGGCCTGGCCGGGGGCCCCTGGCGCCGGCCGGGTGACCTGGAGCTGATCGGCGCGCCGCTGGACTTCCTCGGCGTCAACTTCTACCGCCCGATCACCGTGGCCGCTGCCCCGCACCGCGAGGCCGACCCCGAGCGGCGCACCGCCGTGGACATCGGCGTCACCGAGCTCGACCCGTACGGCACCCGGCACACCACCATGGGCTGGCCCGTGGTGCCGGCCGCCTTCACCGAGCTGCTCCGCGAGCTGCACCGGCGCCACCCGCGCCTGCCGCCGATCTGGATCACCGAGAACGGCACCGCCGAGGCCGACACCGTCGGCGCCGACGGCCTGGTGCACGACGCGCAGCGGATCGACTACCTCGCCGAGCACCTGGCCGCCGTGGCCGAGGCCGTCGCGGCGGGGGTGGACGTGCGCGGCTACTACCTCTGGTCGCTGCTCGACAACTTCGAGTGGGCCCGGGGCTACGCCCAGCGCTTCGGCCTGGTCCACGTCGACTTCGACACCCTCACCCGCACGCCCAAGGACAGCTACCACTGGTACCGGGCCCTGATCGCCGCGCACCGCGCGCGGACGGAGGAAGCAGCACGATGAAGTTCACCGACGGCTACTGGCTGATGCGCCCGGGCGTCACCGCGCGCTACGCCGCCGAGGTCGCCGATCTGCGCGCCGGTGCGGACCGGATGACCCTCTACGCGCCCGTCAAGCCGGTGCGCGGTCGCGGTGACACGCTCAACAGCCCGCTGCTGACCGTCGAATGCTGGTCGCCGGCCGAGGGCGTGATCGGGGTGCGCACCACCCACCACGCCGGATCGGTGCGGCGCGGCCCCGATTTCGCTCTGCCCGGGGCGGTGGCGGACGCCGGCAAGGTGCGCCGGGACGGCACGGTGGCGGAGCTCTCCTCGGGCGAGCTGACGCTGCGGGTGGACACCGCGCAGCCGTGGCGGCTGGAGTTCGGCGCGGGCGGGCGGGTGCTGACCTCGGCGGGCGAGCGCGGCACCGGCTTCGTCACCGACGCCGAGGGACGCCACCACGTGCTGGCCCAACTCGCGCTCGGCGTCGGCGAATCGGTGTACGGGCTGGGCGAGCGGTTCACCCCGTTCGTGCGCAACGGCCAGGTGGTGGACATCTGGCAGGCGGACGGCGGCACCAGCAGCGAGCAGGCGTACAAGAACGTCCCGTTCCACCTGACCAACCGGGGCTACGGCGTCTTCGTCAACCACCCGGGAAGGGTCTCCTACGAGGTCGGCTCCGAGGCGGTGGGCCAGGTGCAGTTCAGCGTCGAGGACCAGACGCTGGAGTACTTCGTGGTCTACGGCCCGACCCCCAAGCAGGTGCTGGAGCGCTACACCGCGCTGACCGGCCGCCCGGCGCTGCCGCCGGCCTGGGCGCTCGGCCTCTGGCTGACCACCTCGTTCACCACCGAGTACGACGAGGCGACGGTGATGCGCTTCGTCGGCGGCATGGCCGCCCGGGGCATCCCGCTGAGCGTCTTCCACTTCGACTGCTTCTGGATGCGCGAGTACCAGTGGAGCGACTTCGAGTGGGACCCGGAGACCTTCCCGGACCCGGCCGGGATACTGGCCCGGCTGCGGCAGCAGGGCCTGCGGATCTGCCTGTGGATCAACCCGTACATCGCGCAGAAGTCGGCGCTGTTCGAGGAGGGCATGCGCGCGGGGTACCTGGTGCGCCGGGCGGACGGCACGGTCTGGCAGTGGGACCTGTGGCAGCCGGGCATGGCCCTGGTGGACTTCACCAACCCGGCCGCGCGGGAGTGGTACACCGGCAGGCTGCGGCAGCTGCTCGGGCAGGGGGTGGACTGCTTCAAGACCGACTTCGGCGAGCGGATCCCCACCGACGTGGTCTGGCACGACGGCTCCGACCCCGAGCGGATGCACAACTACTACACCCAGCTCTACAACCGCGCCGTGTTCGAGCTGCTGCGCGAGGTGCGCGGGGAGGGGGAGGCGATGCTGTTCGCCCGCTCCGCCACGGCGGGCGGGCAGCAGTACCCGGTGCACTGGGGCGGGGACTGCGAATCGCACTTCAACGCGATGGCGGAGTCGCTGCGCGGCGGGCTCTCGCTCGGGCTCTCCGGCTTCGGCTTCTGGAGCCACGACATCGGCGGCTTCGAGGGCACCCCCACCCCGACCGTCTTCAAGCGCTGGACGCAGTTCGGCCTGCTCTCCTCGCACAGCCGCCTGCACGGCAGCAAGTCCTACCGGGTGCCGTGGGACTTCGGCGAGGAGGCCGTGGCGGTCACCCGCGAGTTCACCCTGCTCAAGCACCGCCTCGCGCCCTACCTCCAGCGCGCGGCCCAGCAGGCGCACACCACCGGCGTGCCGGTGATGCGCGCGATGGTCCTCGAGTACCCCGACGATCCGGCGGCGGCCACGCTCGACCGGCAGTACCTGCTCGGCGACGACCTGCTGGTGGCCCCGGTCTTCACCGAGGACGGCACGGTCGACTACTACGTGCCCGAGGGGACGTGGACCAACCTGCTGACCGGTGCTCAGGTGACCGGCCCGCGCTGGGTGCGCGAGCAGCACGGCTTCCACACCCTGCCGCTGCTCGCCCGCCCCGACTCGGTGATCCCGCTCGGGGCGGACGACCAGCACCCGGTCTCCGCCTGGGCGGACGGGGTCGAGCTGCGGGTGCACGCCTTCGCCGACGGCGCCGAGCGCACCGTGCTGATCCCGCGCTCGGACGGCCCCGGAGAGAGCGCCCGCTTCCGGCTGCGCCGCACCGGCGACCGCCTGCACGTCAGCACCGACAGCCCGCACGCCTGGCAGCTGCGCACCGGCGGCCCGGACGGCCCCGTGCACCTGGGCCCGCCCGGGACGTTCGAGGCCGAACTCCCCTTCCCGGTCTGAAGCGGCAGTCGATGCCGGGCCGTCCGCCCCTGCGCGATGTCTTGACGGTGCCCTGGTCGCTTCCCATAGTGATGCCAGCCTGTTAGCGCTAACAATCTGGCGCCTTCCTTCTTCCACCCATGAAGGGGTCCGTCCATGACCACACGATCGTGGCTGCGCCGCGTCCGGCGGGCGGTGCCGGCGGCGCTGTCGACCGCCCTGCTCGTCGCCGGCCTGCTCACCGGCGCGGCCGGCGCCGTCGAGGCCGCCCCTCCGGTGACCGCCGGTCAGGGCCCGTGCGACATCTACGCCGCGGGCGGCACGCCGTGCGTCGCGGCGCACAGCACCACCCGCGCACTCCTCGCCTCCTACAGCGGCCCGCTGTACCAGGTGCAGCGGGCCTCGGACGGTACGGTGCAGGACATCGGGGTGCTGTCCGCCGGGGGAGTCTCCGACGCCGCGGCGCAGGACTCCTTCTGCGCGGGCACCACCTGCACCATCACCCGCGTCTACGACCAGACCGGCGGCGGCAACACCCTGGTCTACCAGGGGCCCGGCGGGACCGGGGGCGCCGACACGGCCGCCACCGCGAACACGGAGCCCCTGATCGTGGCCGGCCACAAGGCCTACGCGCTCTACATCAACCCCGGCAACAGCTACTTCGCCTACAACTCCGCCGGGGGAGTGCCGACCGGCAGCGCGCCCGAGGGCGAGTACATGGTCACCAGCGGCACCCACGTCAACAAGGGCTGCTGCTTCGACTACGGCAACACGGAGACCGACCACAAGGCCGACGGCAACGGCGCCATGGACGCGATCAACTTCGGCACGGAGTGCTGGTTCGGCGGCTGCACCGGAACCGCGCCGTGGGTGCAGGCGGACCTGGAGAACGGCCTGTTCTCCGGCGGCAGCAAGGCGTGGAACCCCGGCCAGGTCTCGCTGCCGAGCCGCTTCGTCACCGCGATGCTCAAGAACGACGGCACCACCCGGATGGCGCTCAAGGGCGCCGACGCCCAGTCCGGGAGCCTGACCCAGCTCTACGGCGGCGCGCTGCCCGGCGGTTGGAGCCCGATGCACAAGCAGGGTGCCGTCATCCTCGGCAGCGGCGGCGACTGCTGCCAGACCAACCACAACGCGAGCGCGGGCACGTTCTACGAGGGCGCGATGGTCAAGGGCTACCCCTCGGACGCCACCGACGCCGCGGTCCAGGCCGACATCACCGCGGCCGGCTACCGCACCGCCACCCCCTTCACCCCCGGCGCGAAGGTCTCGCTGCAGGCCACCACCGCCTGCTGCACCGGCGACTACCTGCAGCACGACTCGGGTGACGACAAGGTGGTGACCGCGCCGGTGACCGCCGCCGGTTCCGCCGCCGCCAAGGGCGCCGCGACCTGGACCGTCCGGGCCGGCCTGGCGAACAGCTCCTGCGTCTCCTTCGAATCGGCCGACACGCCCGGCAGCTACCTCAGGCACTACGCCTTCCAGCTCCACCTCCAGCCCAACGCAGGCACCGGCCAGTTCGCCGCCGACGCGACCTTCTGCGTCCAGCCCGGGAACAGCGGCACGGGCTACTCCCTCCAGTCCTTCAACTACCCGGCCAAGTACGTCCGCCACTACGGCTTCGTCGGCTACCTGGCGAGCAACGGCGGCACCAACGTCTGGGACAACGCGTCGTCCTGGGCCCAGGACAGCAGCTGGCTGGCCGCCCAGCCCTGGGGTTGAGCCACCACCGGGGCAGGCACCACGGCGCACACCGGCCCGCCGCCGCTGCACCGGCGGTGGCGGACCCGGCTCCGAGCACGGGGCGGCCCGGAGCCGCGCGACACCCTCCGACCGCCCCCGGCCCCCAACCTCCAGCCTCCAGAGCAGAGGAGTCGAGCCTTGTCGTACAGCATCCGCGCGGGCGCCGTGGAACGGCACACCGCCGCAGAGGTCCTCCGGGTCGAACCCTGGGGGCCGGACGCCGTCCGGGTGCGGGCCTCGTCCGGGGCCATCGACCCGGCCGCCCCCGGAGCGCTGATTCCACCTCCGTCCGGCCCGCCGTCCGAAGCGTCCGTCTCCCAGGACGGCAGTGCCCGCCTGGTCAACGGCTGCATCGCCGTCGAGGCCTCGGCGGACGGCCGGCTGAGGTTCTGCCACGCCGTCTCGGGCCGCGAGCTGCTCGCCGAGCGCAGCCCGCACGCGCACCACACCGGCCCCCGCGTCCACGCGACGGCCGGCCGGACGGCCCAGTCCTTCGAGGCGTACGAGGGCGAACGGCTGCACGGCCTGGGGCAGCACCTGCACGGGCGCCTGGACCAGAAGGGCTGTGTGATCGACCTCGTCCAGGCCAACACCGTGGCGGCCGTCCCCTTCCTGCACTCCTCACGCGGTTACGGACTCCTGTGGAACAACCCCGCCACCGGCCGCGTCGAGCTGGGCGCCGACACCACCCGGTGGACCGCCGACGCCGGTGGGCGCATCGACTACTGGATCACCGCCGGTGACACCCCGGCCCGGATCCTCGACTCCTACACCCGGGCCACCGGCCGTCCGCCGCTCCTGCCCGAATGGGCGTCCGGCTTCTGGCAGTCGAAGCTGCGCTACCGCACCCAGGACGAACTCCTCACCGTGGCACGGCAGTACAAGGAGCGGGGCCTGCCGCTCTCCGTCATCGTCTGCGACTTCTTCCACTGGCCGAGGATGGGGGACTGGCGGTTCGAGCAGAGCGAGTGGCCCGACCCCACGGCCATGGTCAAGGAGCTGTCGGCCCTCGGGGTGAAGCTCGCCGTCTCGGTGTGGCCCACCGTCGAGCCCGGCAGTGACGCCTTCGACGGGCTGCGCTCGGCCGGGCACCTCGTACGGGACTCGGCCGGCGGTCTGCTCACCCACCCGTGGCCGTCGCGGTACGGCGGGGAGGCCCTGATCCGTCCGATGGCCCACTACGACGCCACCCACCCCGGAGCACGCGCGGCGCTGTGGCGGCGGCTGGACGAGAACTACCGTTCGCTGGGGGTGGCGTGCTTCTGGCTGGACGCCTGCGAGCCGGACCTGCCCCCCGGCCTCGCCGAGCGGGCCGTCTACGCGGCCGGGCCGGCCGCCGAGGTCGCGAACCTCTACCCGCTGGAGCACACCCGCGCGGTGGCCGAGGGCCTGCGCGCGGCGGGCGAGGAACGGCCGCTCTCGCTGGTCCGCTCCGCCTGGGCGGGCAGCCAGGCGCACGGGGCACTGCTCTGGTCGGGCGACATCCCCACCACCTTCGACTCGCTCGGCCGCCAGATCCGGGCCGGCCTCAACGTCGCGATGAGCGGCATCCCCTGGTGGAACACCGACATCGGGGGCTTCTCCGGCGGCGACCCGGACGACCCGGGGTACCGCGAGTTGCTGGTCCGCTGGTTCCAGTACGGCACCTTCTGCCCGGTGATGCGGCTGCACGGCGACCGCGCGCCCAACTACCCGACGTTCTCCACCGACATGACCGGCGGGCCGAACGAGGTCTGGTCGTACGGGGAGCAGGCGTACGGCATCCTCCGCGACCACCTGCTGCTGCGCGAGCGCCTGCGCCCCTACCTGCGGACGCTCTCCGAGGACGCCCACCGCACCGGGGCCCCGCCGATGCGCCCGCTGTTCTTCGCGTTCCCCGAGGACGAGCGGGCCTGGGCAGTGGACGACCAGTTCCTGCTCGGCCCCGACCTCCTGGTGGCACCCGTGTACCAGGCCGGCGTCCGGGCCCGCCGGGTGTACCTGCCGGTCGGTGCCCGCTGGGTCGACCCGGTCACGGGAAGCGCACGGGAGGGTGGCACGACGGTCGACGCCGAGGCTCCGCTGGAGCGCATCCCGGTCTTCGTGCGGCACGGGGCCGAGGTCGCAGCGGTGTTCGGCTGACGGGCGGTCCGGACAGTCGAACAGTCAGTTAACGCTAACAAAAGCTTTGGGCACGAGGTGGCATGGCTCGATAAACCTGCAGGTCAGGGCAGTTTCCCCTGCTCTCTGCCGGTGTTGACGATCCCATTGATCGCTCATACGCTCCGGGACACCGGATCACCGTGGTCGTACTCCGATCGGAGCACCGATGCCCAAGCCCCGCCTCCGCCAACTCCTCGTCCGCTCCCTCCTCGTGGGCGCACTCGGCACCACCGCCGCACTGGGCTCCACCACGGCGCAGGCCGCCACTCCGGCGGTGGCCAGCCCGGCCGCTGCCGCGCAGGCCACCGCCGGGGGCGGGTCGTTCTCCGTGCTGACGTACAACGTCGCCGGGCTGCCGCAGGTGCTCTCCAGCGCCTCGACCGACCGGCAGAGCAGCACCACCGCGATCGGCAGCCGGGTGGCGCCGTACGACGTGGTGAACGTCCAGGAGGACTTCAACTACCACGCCGCGCTCTACGCCACCGACACCCACCCGTACCGCACCGCCACCAGCGGCGGAGCCGGCATCGGCAGCGGCCTCAACACGATGTCCCGATTCGCCTACGACGGCGACGACTTCGAGCGCGTCCACTGGCACGACTGCCAGCTGGACTCCGGCGACTGCCTCACGCCCAAGGGCTTCACCTTCATGCGGACGAGGCTGGCCGAGGGCGTGTACGTGGACTTCTACAACCTGCACGCCAACGCGGGCACCGAGCCCGGCGACGAGGCCGCCCGCGCCGCCAACCTGGCGCAGCTCACCGGCTACATCCAGACCCACTCGGCGGGGAACGCCGTCGTGGTGATGGGCGACACCAACACCCGCTACACCCGGGCCGACGACACCATCGCCGCCTTCGCCGCCGACAACCGACTGACCGACGCCTGGGTGCAGTTGGAGCGCGGCGGGGTGCCGCCCGTCAAGGGCTCCGACCCGCTGCTGTGCGACCAGAACGCGCCCACCGACACCTGCGAGATCGTCGACAAGGTGCTGTACCGCAGCAGCGCACTGGTCACGCTCGGCGCGACCTCGTACGCCGACAAGCACGTCGACTTCCTGGACGGCGCGGGCAAGATGCTCTCCGACCACGACCCGGTCGCCGTCGGCTTCACCTGGAGCCAGAACCCGGCGTACCAGGCGAGCGAGCAATTCGGCGGCCCGCACGGCGACTTCTACAACGACATCGACCGCGTCCCGGCAGGCGCCCAGGCCGCCGTGGTCAGCCTGCGGTCCGGCTCCCGGGTCGACCAGGTCGGGCTCACCCTCGCCGACGGCACCTCGCTCACCCACGGCGGCACCGGCGGCACCGCCGCGTCGCTCACCCTGGGCGGCGGTGAGTACGTCAACTCCGCCACGCTGTGCGAGGGTTCGTACAGCGGGCACACCCGGATCTTCTACGCCTCGTTCGGCACCAACCTGGGCCGGTCGCTGGCCGGCGGCACCACCACCGCCGACTGTGTGACTCGCACCGCGCCGGCCGGCTGGCAGTTCGCCGGCTTCCAGGGCCGCTCGGGCGACGAGGTCGACAAGCTCGGCTTCCTCCTCACCCGCCGCTGACCACCCCGCACCTCCCCGGCCCGGGCCGCCACCCGGGCCGGGGAACCCGCACGTCCGCAGACCACCACCGCAGGAAGACGCTCATGAACGATCAGCCCACCCTGGACCGCCGCCGATTCCTGCGCAGCTCCGCAGCCACCTCGGTCGCGCTGCTCACCGCGCCCACCGCGCTGAGTCTGCTGACCGCCCCGCAGCGGGCCGTCGCCGCTGCGCCCGTCGGTTCGGTGGCCGGCGGCTCCGCGGCGGGCCACTCCGGGCCCGTCGGCCCGGTGTCCGGCCCCGCCTTCGTGGACTCGTACACGACCAACACGATGGCCGACCTCACCCCCACGGGGAACGCGGCCGTGCGGATCCTCACCGGGATGAGCCGGATCTGGCGGACCGGCGGGGCTTGGAACGACGGCTCGCCGCTGCTGGCCGAGGTGCTGCGGGCCAATGTGCGCTCCTGCGTGCAGGCCACCACGCAGCGGACGGCGGAGCAGGCCAAGGAGGCGTTCATCTACGACCGCCAGCACCAGAGTTACGCCGTCATCGCCGGGCTCGGGCCACTCGCCGAGCTGTACCGGACGGGCGCCCGGGCCGTCACCTCGATCACCACGGCGCCCGACTCCACCCCGCCCGGGAAGATCGACGACGCCGTCCCCGCCGATGCGCCGGCCGGTTCGGCACTCGGGCCCGGGGCGGTCGACTCCGAGCTGGGGCGGGTGGTCACCCTGGTCAACACGCTCCGGGGGCCGTACGCCTCCGGCAACCCGGCCAAGTACGCCTACCGGTACCCGAGGCCCTGGCGGCTGAACGGGCAGAGCGCGGTGGTCGACACCGGCGCCACCGATGCCTTCGGCTTCCCGGTGTACGCCTCGGAGGTGGTGGTCGCCCCGCAGCTGCTGCGTCAGCGCAATGCCTCCCCGGCCGACGACGGCGGTTTTGTGAGCGGTCACACGAACGCCTTCCACCTGGCCGCGCTGGCCCTCGCGTACGCGGTGCCCGAACGCTTCCAGGAGCTGGTCACCCGGGCGTTCGAGCTCAGCCACACCCGGATCACCGCCGGCATGCACTCCCCGCTCGACGTCATCGGCGGCCGCACCCTGGCCACCGCGCTGGCCGCCGCCACCCTCGCGGACCCGCGCAACGCCGCTCTCAAGGCCGCCGCCCGCAGCCAGGCCGCCGCCTACTTCCAGGCGAGGACCGGCAGCTTCCAGGCGAAGACCGAAAGCTTCCAGGGGAAGACCGGCGGCACCACCGACACCCTGTACGCCTTCGCCCACCGGGCCGGTACGGCCGAGGACCCGTACGCCGACCGCCTGGCCAACGCCGCGCTGGTCAGGCCGAAGCTGACCTACGTGCTGCGGCGCGGCGGCCGGGAGGTCCCGATGACCGTGCCCAAGGGCGCCGAAGTCCTCCTGGAGACCCGGTTGCCCTACCTCGACGCCGACCAGCGGCGGGAGGTGCTGCGCACCACCGCGCTGCCCTCGGGCTACGTGCTGCTCGACGGCCCGGAGATGTGGGGCCGGCTCGACCTGTTCGCCGCCGCCGACGGCTACGGCTCCTTCGAGCGGGACGTGACGGTGGAGCTGGACGCCGCCGAGGGCGGGTTCTGCGCGGCCGACGCCTGGCGCAACGACATCGGCGGGCCCGGCGGTCTCACCAAGCGAGGCACCGGGACGCTGACCCTGACCGGCACCAACCGGTACACGGGCACCACCGTGGTGGCGGCCGGCGCCCTGGTGGCCGGCTCCCACGACGCGCTGGGGCGCGGGGACGTCCAACTGCGCGGTGGCACCCTGCGGGTGGACGCCGAGCGCGGTCCGGTGCGGGTGCACGGCGACTACTCGCAGGCGGGGACCGGGACTTGCCTGGAACTGACAGCTCATCAGCTCCACCGTGCGGTACTGACGGTGGCGGGCCGGCTGGTGCTCGGCCACGGTGCCCGGCTGGCCCTGGAGCTGCGGGAGATCGGGCCGCTCGGCGAGGAGGCGGTGCTGCCGGTGATCAGCGGGTGCGCGGTGCAGGGCGGGTTCGGCAGCGTCACGGTGGACGTGTCGGGATACCGGGCGACGCCGCTGCGCACCCGCGAGGGCATCTCGGTGCGGCTGACCCGCTGCTAGGACCGCCGGGGGCGGTCGGGCGCAGGGTGGCTGGTCCGTGCTGTGCCCCGGGGCTACCCGGTGTTCAGTCCGGCGCGGACGGCGCGCGGGGAGGCACCGAGGTCGCGGCGGCAGGCCTTGTTGAAGGCCTGGAGGTCGGGGATGCCGACCGAGGCCGCGATGGCGGGGATGGACAGGGTGGTGGCCTGGAGGAAGTGGCGGGCCCGCGCCATCCGGCGGGCGCGGAGGTAGCCGACGACGGTGGCCCCGGTGGCCGCGCGGAAGAGCCTGGTCAGGTGGTTGTGCGAGACGCCCGCCGCCCTTGCCAGCTCCGCCACGCTCAGCGGCTCGGCCAGGCGGGCCTCGATCATCGCCAGGGCGGCGGCGACCGCCGGATGCGGTGCGGCGGTGTCGGCCGTGCGCAGCGGAGCCAGCTGGGCCACCCGCCAGAGCGCGGCCCAGACCTCGGCCGTCGCCCGTACGGGGGAGTGCGGCCAGGCCGCCAGTGCACTGGTCAACTGCGCTCTGAGCGGTGCGAGTTCGGTGCCGGTGTCCTGGATCACCGGAATGCCGATCTGCGGGCCGGCCGTGCCGAGGCGCAGGTGCACGTAGAGGTGCTCGGAGCGGCCGCGGTAGCGGTAGCGCACGGTGGTGCCGGGCGGCACGAGGCTGACTCGGCCCGGGCGGATCGCGTGCGCGGTGCCGTCCACCGTCAGCTCGGCCTCGTAGCCGTAGAGGTGCAACTGCCAGAGGTCCGGCAGCAGGAACACGTCCGTCCGTCCGGCGCAGCCGTGCACGCCGATGCCGACGGCGGCCACGACGGGCGGGTCGTCCAGGTGGGCGAGTGCGGTGTCCATGGCCGAGTTCTATCACCGTGCCCGGAGACGGAGACGGAGACGGAGACGGAGACGGAGACGGAGCGGGTCCTGCTGCCAGGACCCGTGCTCAGCCGAACGCCCGGAACGGTCCTGGGTGTTCTGGTCCACCGAGTTCGGCCCGTGTCCGGCTCCGACTGACGCTGGTCGGGCAGCTTCCGGCCACCCCGCACGACGGAGACCAGCTGGGCATGGCCGGGCAGCATGCTGGTGATCCGTACCGGACCGGGGTTTGGGGTCATGCGGCGGGTTCGATGCCGAGGTCGGCGAGCAGGCCGCGGATCCGGGCCTCGATCTCGTCGCGGATCGGCCGGACGGCGGCGACGCCCTGGCCGGCCGGGTCCGCCAGCCTCCAGTCGAGATAGGTCTTGCCGGGGAAGAACGGGCAGGCGTCGCCGCAGCCCATCGTGATCACCACGTCGGACGCCTGCACGGCCTCGACGGTCAGGACTTTCGGGGTCTCGGCGGAGATGTCGATGCCGACCTCGGCCAGGGCCTCGACCACGGCCGGGTTGACGGTCTCGGCCGGGGCGGAGCCGGCCGAGCGGACCTCGACCCGCTCGCCCCCGAGGCGGGTGAGGAAGGCGGCCGCCATCTGGGACCGGCCCGCGTTGTGGACGCAGACGAACAGGACGGACGGGACGGCGGGAGTGCTCACGGCAGGGGTCCTTCGGTCTTCGGGACGAGCAGGAGGGAGCGGGTCAGCGGCCGGCCGGGGCGGGCTCGTGGTCGCCATGCGGGACGACCACGTGCTCGGCGACGTGCTCGGTGTCGTGCTCGGCGACGGCCGGGGAGGGTCGGCCGAACAGGACCGCGACCAGGCCGAGCCCGGCGGCCAGACCGGCGAGCTGGGCGGCGATGAACGGCAGCACGGAGGCGGGGGCGACACCGGCGAAGGTGTCGGTGAACGCCCGGCCGATCGTCACCGCCGGGTTGGCGAAGCTGGTGGAGGACGTGAACCAGTACGCGGCTCCGATGAACGAGGCGACCGCGACGGGGGCGAATCGCTCCCGGCCGACGCGGGCCAGGCCGAAGATCAGCAGGATCAGGCCGGTGGTCGCGACGACCTCGCCCAGCCACAGATGCGGCGCCCACCGGTCGTGGGTCGACCAGGCCACGGGCGTCTTGGCGAACATCGCGTCCGCGAGGACCGCACCGCCGATCGCCCCGGCGACCTGAGCGCCGACATAGGCCGCGACCTCGCGCAGGCCCGGGCCGTCGCCGTCACGGCCGGTCCACCAGGCGGCCAGGGTCACGGCCGGGTTGAAGTGGGCGCCGGAGACCGGGCCGAGCAGCAGGATCAGCACGCCGAGGCCGAACACGGTCGTCAGCGAGTTGGCCAGCAGTTGCACGCCTACGTCGCCGGAGAGCTGGGCGGCCTGGATGCCGGAGCCGACCACGACGGCGACCAGCGCGCCCGTCCCGACGAACTCGGCGGCCGCGCGGCGCCCCAGCGGGGCTATCGCGGTCATCTCGCGCCTCCCGCGCCGGCGGGAGTCTGGAGCAGGGTGGAGAGCTTGGCCAGGGCGGCGGGCAGCACCCAGTAGTAGACCCAGGTCCCCCGGCGCTCGGAGCCGACCAGCCCGGCCTCGCGCAGCACCTTGAGGTGGTGGGAGATCGTCGGCTGGGAGACATCGAAGGGGCCGGTCAGGTCGCAGACGCAGGCCTCGCCGCCCTCGTGGGAGGCGATCAGCGACAGCAGCCGCAGCCGCACCGGGTCGGAGAGGGCCTTGAACATCTTCGCGAGGTCGGCGGCGGCTTCCTCACCGAGCGGCTCGCGGGCCATGGGCGAGCAGCACGCGGCCGGCTCGTCCTGGCCGAGCACCGGCAGTTCCAGATTCGACATGCATCTATGTTGACAGTCATCTATGCGAGTGGCAACGTCGCCAATATCGACAATTGTCGAATCAAGACCTCGGATCGGGGAGACCGCCATGCGTGCGGCTGTGACTCAGCACGCTACTTGTCGCTAACCGCACTACTCGACGTGCGGCTCTCCGGGCGGGTCAGCATGACAACTGTCGCCGATTCGGCGAGGTATCTGTCGGCTGGTGATCGTTTGGCAAGCAAGTTGTCGCCAACTCCGAAGAAGTCGCCCCGCCGACGCGAGCTGACTACTTCGATGGCGGGGTGGATACGTCACGCAGGACTTTCCCGGCACCGCCGACGACTCGCGGCTCTACGTACACGGGGCCGCTGTGGTCGCATCTGTGCAGGTGGGAGGACCTGCTGGTTCCTGTCAGTAGGACGGCAGGTCGCCAGGGTCTGGCCCTCGGCGAGGGGTGGACGCGTCGATGGACAGTGACGTGGCGTCACCGAAGCGGCGAGGTGACTGGCGCGGTGGCCTCTCTGGGGCAGGCGCCCTGGGTGGGCTGCGTCCCGATGCGCGGCTTCGCTTGGCGGCGTGACCAGCGGCATCGGCCGGGGCTGGAGTACCTGGTCAGCACGGGGCGGCTGCACGGCTTCGAGAGTCTGGAGGAGGACTGGCTGCTGCGGGCGCTCGATTTCTGCGGCGGCGTGCAGATTCTGCTCTCGCAGCCGTTCCGGATGCGCTTCGAGGCGAACAGGCGCTTGCGGCGGCACACTCCGGACTACCTCGTGGTCTCCGATGACGGGGTCTTCGTCGTCGACGTCCGTCCGGCAGGGCTGATCAAATCCGAGGATGAGGAGTCCTTCGCTGCGGCTCACGAGCTCTCGCTGGCCTCCGGCTGGCGCTACGTGGTCGCGGCCGGCTGGTCGCCGCACGTCCAGGCATCCCTGGACGCGATGTACGCGCGGCGACGCCCGATGAGCGACCCCTTGAATCTGCGCCCGGAGCTACTCGCGGCAGCCGAGCAGGGTGTGACCTTCCGCGAGGCCGCGATGGCCTGCCAGTTCTGGCCGGTCGCGCGGGCCCAGCTGCTGCACCTGTTGTGGCAACGGCGACTTGGCGTTGATCTGTCCGAGCCCTTGACCGATGCGTCAAGGCTGATGCCGGCGGAGGTGTCATGAGCGCGGGCGCCTTGGATCTGGCTCCGGGGGCAGCACTGGTCCTCGACGCGAGCGAGTGGCTGGTCGAGCGGCAGGAACCCCATCTCGGCCGAGTTCACCTGATGAACCGGGCCGGTGTCCGGCAGTGCGTCAGCTTCAGATTCCTACTGAACCATCCGCAGTGCCGCAGCTCGTCGCTCACCTCCTCGTCCGGCGCGAACCGGGGACGGCAGGAGATGACGTTGAAGGACCTGAAGCCGGAGAAGGTCCCGCTGGTGGAGTTGCGGTTCGAGCACCTGATGGAGGTCTTCTGCGACTTCCGCAGCGGAGACCCATTGCACCCGCGGCCAGGAGATCCTCGCCCGGAGTACCACCCCGACCGCACGACCGTGTCCGAGCGACGCCAGGCTAAAGTGGCCGAGCTGGACGCCATGGACCCGGCCGCCGCGAATCTGCTGGCGCTGGACCGGGTCGGCGTCAGGACCCTGGAGCGCTGGGAGCGCAAACGGCGCCGCTTCGGGGTGATCGGCTGCGCGGACGACCGATGGCTGCGCGAGAGCGGCGGGCACCCCAGCATCTCAGAGGAGATCCGGGAAGCGATCCTGGCCGTTCGGGAGGAGACCCGGCTTCACCGTTCCAGGGTGGACGCCCGCACCCGGGAGACGATGATCCACCGCTACGTCCGCGAGACGTTCCCCGGCCAGGAAATCAAGGTCCCCAGCTACGACACGCTCAGGCGGGTCTGGCACGAGTGGTTCGGTCCCGGCCGTGGTGGGCAGCGCTACGAACGCTCCGCGTCGCTGCCCGAGAAGGACGGGCACGGGCTGGTCACCAGGCCGGGCCAGGCGGTCGCGCTGGACACGACGATCATGCCGGTGATGGTCCGCGAGGGGGTCTTCGGCGACCCGGTCCGCGTCCACCTGACGCTGGCGCTGGACGTCTACACCCACTCCATCTGCGCTTTCCGGCTCACGCTGGTGTCGGACACATCGGTCGACGTCGCGATGGTGCTGCGGGACGTAATGCTCCCGCTGCCCATGCGGGCCGACTGGGACGGCGAGATGGAGTGGCCCTACCCGGGGCTGCCGGCTGCAGTCGTGGCGGAGTTCGTCGGCCACCGGGTCGCGGCCCTGCCGTTCTTCGCGCCGGAGACGGTGACCACCGACCACGGCAGCGTCTACCGCAACCACCACCTGGTCGAGGTCCAGGAGGTGATCGGCTGCCGGGTGCTTCCGGCACGGGTGCTGCGGCCCCAGGACAAGCAGGCGGTCGAACGGGTCTTCGGCAGCATCCGGTCGCTGCTGTTCGAGCACCTTCCTGGCTACACCGGCATCGACACCGCCGACCGCGGTGCGGAACCGGAGCGGGACGGCACCTTGACCATCGACGCGATGGAACACGTGATCGCGACCTGGGTCGTCAAGGTCTGGCAGAACCGCCGGCTGGGCGACTACGCGCCGGCGTGGGATCCCGGCGGGGACCACAGCCCCAACTCGCTGTTCGCGGCGTCGTTCGCGCAGACCGGCTTCGCGATGGAGATCCCCCAACCCGAGCTCTACTACCGGTTCCTGCCGGAGCACCAGGTCAAGCGCATCCACGGCCGCCGGGGCGTGAAGATCAAGGGCCTCTACTACTACGGCGATGCACTGGAGCCCCACTTACACGAGGCATCCTCGCGCGGCGGGCGGCGCAAGCAGATGTGGATCATCCGCCGAGAGCCCCGAGACCGGCGCGTCGTCTACTTCCAAGGTCCCGTTACCCACGAGTGGCACCCCCTGCGCTGGACCGGGCTGCCGCCGGAATCGCAGGTCCCCGCCTTCGGTGACCTGCGCGCCGAGGAACTCCTCACCCGAGTTCGCGAGGCCGGCCTGCGACCGCGGACCGATGCCGAACTCCTTCCGATCCTCCTGGACCTGCTCGGCGCCCGTGATCCGGTCAGCAACTGGCCCAGCCAGATGACCAAGTCCCAGCGCGTCGAACACGCCCGCGAGGCCACGCAGGCCCAGGCGGCCTCGACCGACCGGCCGGCGGCCTCCGCCGAACCCACCCCACCAACCCGTCAGCCCCAGCAGACCGCGGGGAACGTGCTGCAGTGGCCGCAGCGGGCTGGGCAGACCCGAGGCAGTCTCGACGCCGAGCGGCGCCGCCGGAGAGAAGCCACCGTCCCGGTCACCCCGAAGCCACCGCCCCGGCTGGGGTCGAGCTTCCGCGAGCGCAACGTGTTCCTCCTGCCCGAGGACGACGAAGAGGAGCACGGTGGACAACCGGCCGGCTGAGAGCGACAGCCCGATCGTCCCGTTCCTGCGCGTCGGACCGCCGCCCGACCGCACCAGGTGGGAGGGCTGGCAGCAGTGGCGCGAAATCCGCGACACGTTCATCCCGGCACCGCGGCTCTCGCTGAAGACCTGGGCCAGGCTGATGGCCCCGCCGACGAATCGGTCGTCTTCTTGCCAGCCGGGTTCGGTGGCGGTGTGGCTGGTCAGCGCCTGCACGAGCTCGTCGTCCATCATGGCCTGGACGGCCTCCAGGGTGATCGGCGACTGGAGCTGGAACTGCGTGATGGCGGCGAAACCGGAGCGGGGCGGGGCGGCGTTCACGGTGTCGTTGCCGCCGAGGTCCGCGTCGAGCTGGCTCCGGCGGTGCCGGGCCTGCTCGGTGAGTCGCGCGTCCGGGATGGCGGCCAGGAGGTGGCGTGCGGTGGTGCCTTGGGGGATCGTTCCGTTGTCCTCTAGGGGGCTTGTCGCGGAGGCGGCCCGCTGCTGGGCGGTGCTCGTCTGCTGGGGGGGCACGCTGCTGGCAGACGTGGGCGAGCGTCTCGGCCGAGAACGCGGTCTGGTTGAGCAGCCAGTCTTGGACGAGTGCGAAGCGGCTCTCGTTCAGCCAGGCGAGTGCGTCGTCGACCATGTCGGGGTGGCCGGAGGCGAATCCGGCGGCTGCGAGGGTCTGTTCGGTGGCGAGGGCGGAGTGGGCCATCTCCCGGACGGCGGTGTGGGCATCCGCGTCCCCTGCAGCCGCGGCGATGCGCAGGGCCTGGGTCAGGTGTCCGAGGACGGCACCGTTGTCGCTTCCGACCGTGGGCGGTTGGTGGGGGCGGTGCGGGAACGTGGCGTCCGTCTCCCCGTTGGCTGCGAGCGTGCCGGTGCGGGTGGCGGTGCTGGCGGCACGGGCGACCGGCAGGACGTGATGGACGAACGCGGCTGGGTCCTGCTCGGCGATCTTGCCGATGACGTTCCAGGCCGTGTGGCTGCCGGTCCCGAGTAGCTGCACGGGACGTGGTCCCGGCGCCGGCGGCGAACCCGCTCCGGTGTCCGGCTTGTCCTCGGTGGTCGTGGCGGCAGGGCCCTGTCCGGCCGTGTGCAGGTCGAGGCGCCGCCGCATGTAGGCGCCGACGATCCGGGCTCCCGCAGCGGCCGCCCCGTCCGTGGTGCCGTACAGGAGGGTGAAGACGTCGTGTGATGCGCGGAGCCCACGCAGGGTCGCCGGCATGGGGGCGCAGCAGTGCGGCCACCTGGTCCGGGTGGTGGCTGACCAGGATCCTGCAGCCAGCGGGAGCTCGACGAGCAGTACCGCCGGGCACTGGAGGTGAACCCTGGTCAGACGAACGCGATGCGCTCGGCCGGATCCGCCCGCGGCGGCCGTGGGGCCTCCCGCAAGGGCACCGGGCTCTACGGCTAGAAGGACAACCCTCTGAGTTCGCCGTGCTCGTCGGCGAGTACGCGGGGGTGACGATGTGGTGCCGACGCTGGCCTGCGTCGCCCGGCCTGGCAGCGTCGTCATCCCCGGCTCGGTGTCGTTCAGTACAGGGGTTCAGGAGGTAACCCTGAGCGTCAGCTTCTGGAGTCGACGGCCCGAGGTCGCGATGTCGGACGTCGGACCGACGGGCGTTCTGCAGGGCTGTCTCGGCCAGGGCCGTCCGCCGAACAGCCGCATCTCCTCGCTGGCGAGCCGCTCGCTGGCGCCGTCCGGGTCACCCCGGAGAAGTTGGTCCTTCTCGACCCCCGAGGTGAGCAGTACGCGCAGGCCGCTCTCGCCGTGCCGCGCTGTCCAGGAATTCACCAGCTCCGTCTGGTGCTTCGTGACGGTTGCCTGGGTCTCGGCCTGGAGGCGGGACCGCAGCAGCGCGAGGGCGGCCAGGACCGTGTCCGTGTCCAATTGCTCGGACCGCGCTTGGCCAGCAATTGGCAGATCCGCCGACCGGCAGCCGAACAGGAATCTGGCAGCGCTTCAATTGAAGCGCTTCAAGCGCTTGAAGCGCGGGGCAGTCACGCCATCATCCTGGCCCGCTGCTGGGGCTGGTGTCGGCCGGATGCCGGGGGCGGGGGACGCTTGCCACCCCTCGGCCCCCGTAGCGGACATCAGCAGTCTGGCCAGCGACAGCCTGCCCGACGTCCGCTCCCAGCGGCTCGTCCGCTCCCTCAACGACATCGCCGACGCCCTGCGAGCCCACCGGACCGTGCCCTGCGTCGCCGAGTACCTGGACACCCACCACGCCGCCCACCTCCCACCCACAGCCTGAAGGACCACATGAGCCCCGCACTCGCCCTGCAGCGCTACGGCGCTGGCGACACCACCGACCTGCTCGACACCCTCGCCGACGTCTGGGCCGAAGCCCACACCGGCCACCACGACGTCGCCGCCGCCGGGTTCACCCCCGACACCCTGCGTCGCCAGATCACCGGCCACGCCCACCACGACGGCTTCGTCCTCGTCGCCGCCTACGCCGAAGGCCAGCTCGTCGGCTTCGGCTACGGCTTCCGCTGCTCCCCCTCTTACTGGTACGGCGAGCAGCTCCGGCCGGCCATCACCCCCGACGCCCGCGACACCGACAGCCTCGCCGGGATCTGCGAACTCGCCGTCCGCACCGGCTGGCAGGGCCGCGGCGTCGGCACCGGCATTCACACCGCGCTGCTGGAGGCACTGCGCACCGAATGGGTGTCGCTCCTCGCAATGCCCGACAACGGGCCCGCCCGGCAGCTCTACGATCGCCTGGGATACCGGTACGCCGGCCCCTACAGCGCCGGCCCCGACGGACCGGTGCTCGACCTCCTCCTGCTCCGCACGCCCCTCTGACCGGCGCAGCGCACCGGGCTCCGGCCAAGGCAGCGCCGGACCGACACCCCGGAGAGCCATGACCACCGCCACCGCCCGGTTCACGCCCGGCAGCACCGCCGTCCGCCGCGACGTCCACCACGGGCGCGTCTGGTCCGCCCAGCCCTACCGCACCCTCACCGACGACGGCGATGTCCTCGAACTCCTCTACTGGCCCGGCCTCACCAGCCTCGGACCGACCACGTGGTCGGACGCGATGCGCACCGGCGACCACGCCCTGCGCCAGTCCGGCCTTCAGGACCTCGCGGCTGGCAACTGGCAACTCGGCCCCTGGACATGGGAGAAGACCGCCCTTCGCTCCCGCCTCGAATCCGGCGCCTACTTCAGCATCCACACCTTCCAGGACGCCGCCACCGGCGAGCCGCTGCGTTGGTACGTCAACTTCGAGCTCCCCTACACCCGTACCCCGATCGGGCTGGACACCTTCGACCTCTTCGTCGACCTGGTCGTCGAACCCGACCTCAGCGCCCACCACTGGAAGGACGTCGACGAGTACGAGCAGGCACGGCACCTCGGCCTGATCGACGACGACCTGCACGTCCAGGTCGAGGCCGCCCGCGAGCAGGCCCTCGGGCTACTCCAGGACCGCCGTGGACCCTTCGCTGAAGCCTGGCCGACCTGGGCACCGGACCCCGGCTGGCCGCACCCGCAACTGCCCTGCGACGCGGGCGACTACGAAACCGGCCGAGCGCGGTGAGCACCGCCGTCGAGCCGCTCGACCCCCAGCACCTGGAGCTGGTCGAAACGGCAGCCCTGCCCTCTCGGCCGAGCCGCGGGCACATGGACCGGATCTGGGCTACCCGGCCCTGCTCAACGGGCCGGTGATCGCCCGTCTCTCGCTGCCGGTCTGCGCCTCCGGGCAGCCGGTCCTGACCTGAGCGCCAGTCACCTACTGGTACCGAATGCTGCGCCTGATCCCTAGCGCGGAGGCCGTCGGCGGTCTTCGTGACCGTCCTGAAGGTGCCGACCACCACCGGGTCAGGTCACTGGCGCTTGCGCCGCACACACCGCGCGGCGAGTTCTACCCCAGCGTGCACCGCGAGCGCCAGGCTGGCGGTGGCTACGTTCGGATTCTCGGGTCGCTCTCCTCGAACAAGCTCGACCTGGTCGAGCACAACTGGCGGCTCTACCGGAACCACGAGAACCTGTCGCTGGCCCGGTCGCCCGTTCCCTGGCCGGCGCCGCGTGGCACTCGGTCCGCAAGTCCCGCATCTAGGCCTCACCCCCCCGCCGAACAGGTACACCCGCCCTCCCCTGCCCCCGACCCGGTAGCGGGAAGCCCGTACGAGCGGGAGGCTATCGTCGAACCGGGCGGCGTCACCGGTCAGTTGCACCACCACTGCGACTCTGCCTGGGGTGAGGGCAGCCGTCGTGGCTGCTGCGGGCACACGCACGGATGGTGCTGCAACCCGGCCACGCCGCCCGTTGGTAATGCCCCTCTGTACTGCCAGTCGGTCGGTGCGAGCTTCACGGCGGCGTCCGCGATGCGGCAGGCCGCGACCGTCACCAGGGCCGCGCGGCACCGGTCGATCTTGCCCTGCACGGCAGAAACGCCTCCGGCCCGGTACTCCAGGGCGCGCAGCAGGCAGTCGAGCTTGTCGGCGTCCCGGGCGCAGCGTGCTTCGGGTGTGGTGCCGTCCTCGAATTCGGCGACGGCTTCGGTGAAGACGTCGCGGACGGCGGGGTGGGTTCCGGTGACCTGGTCGGCCAGGACTTTGCGGGGGTCGGCGGTGGTGGCGTAGCGCTTGGTGAGGGGGGTGAGGTCGCCGGTGCGGGTTTCGGGGAGGTCGTGGAGGGTGCACAGCAGGGTGGTGCGGGCCGGGTCGGCGCCTTCGAGGGTGGCGAGGGTGGCGCCGATGACCGAGGTGCGGTGGCTGTGCTCGGCCACCGTCTCGGTGATGGCCAGGGGGATGCCGTCCTGGCGCCATCCGGTGCGGGGCAGTCCTCGTAGGGAGCCTGCTTCGAACAGGAGGTGGGCGATGCCGGCAGCGTCCGCGTCGTCGAGCTGGTGCTCCACCTGGTCCTCCTGGTCGGTGGTCAGTTCCCGGTGCGACCGTAGCGCAGGCGCTCCAGGTCGCGGCGTGAGGTTGCGGAGATCAGCGACCCGTCGTGGAGTTCGGCGGCAAGCTCGTAGAACGTCAGCGCGGTGTCCGGTGCTGCGTGCGGAAGCCATGGGTGCAGGAGCAGCAGGGTGCTGACGGAGTGGATGTAGAGGTCCAGGGTGCCGGGGGCGAGGTGTATGGAGCCGACGAGGGACCGGAAGAGCCGGATCGGATCCCAGGAGCCGGGGTTGGGGTGGTTCATGAAGCTGTCGTCGGTCTGGTCGGCGGGCATCGCGCCGAGCCACAGCGCCCAGTAGGCGAGGTTGTAGCCGCACTTTAGAGCTGACCGTTGACCGAACCTCTCTGCCAGCCCCCACCACGGGTGCCCTTTCAGCACATCTCGGGAGTGGCTTTGTTCATGAGTTGCGGGTTCTGGCACAGATCTTGGGGAGTGGTCGCGGAGAGTGACGTGCGAGCGTGGAGCCCGCTGCCCTGGCCCGAACACTCGCCTCGTACTCTGCAGGCATGACCGATGATCCATTCCAGTGCCGCTGCGTCCTGTGCCACGACTACGGTGACCGAGATGAAGCCGACCAGGTTGAGCGGACGATCATCGGCAATGTGCAGGAGCACGGCTGGCACGTCGCCATGGTGCCAGAGGATGAGATCGGCCCAGGATTCGCCTACACGATCGGCCTGGCCCACACGCACGGCACGCCTGAGCTCGCGATGTTCGGGCTCGATGTGCACCTCATGCACCGTATGCTCAACACGCTCGGCGAGAAGGCCGCGTCGAGCACGGCCCTGGCTGACGGCCAGGAGCATCACGGCATCGCCCGTGGTCTGCCCGTGAGGCTCAGGCGGGCGGATCTTCGCTGGTACAGGACCTTCTTCGGACGGGCCATCGGGTTCTACCGGCGTCCGCCCTTCCCGGTCCTACAGGTGGCCTGGCCCGACGCGAACGGGCGCTTCCACTGGGAGGAAGGCGTCGAGCCGGGGCATCGGGACTCGCAACCCCAGCTGTGGCTGTCGCCGGGCGAGCATCCAGCCGGAGTCTGGACGGCCGAGCTCTGACCTCGGCCGCGGGAATCTACTGGAGCAGGATCATCTTGCGAAGCAGCTTGAAGCCGGCTCGCTCGTAGAGCTGCCTCTTGATCTTTTTTAAGATGCTCAAGCGCCAGATGTTCGGCCGCTCCGGCTTTCAACTTCTTCGCGCGTGCTGCTGGCGTGGCCGGTCCGCACATGTCCCGGCCGCTGGCCGCCAGTGGCTCCGCCGAGGGCTGTACGTCAGCCGAGCCTGTTTGCCGCCTCGGGCCAGAGTCGCATGTCCGAGGTCTCGTCCATCTGGTCGTCCTCGTACCAACCACGTCGGTCCAGCCAGGTTCGCAGCCACTCGGCGAGGCTGGGTGAGTCAACGAACCACACCGTGGAGGCGTCCTCGCCGTCGAGCGCGTTCGGCTCGAAGAGCAGGACGGTGCCGTCGGCGCTGCGACAGTCCACGCAGGCCAGCATGCCGCAGCCCCAGTCAAGGATCGGCAGAACGCCTGCGGGCCACGACAGCACGGGGTCCGAGTGGTCTGCAGATGCGAGGGTGTAGTTGCCCAGCGCGGTCTCCATGCTGTCAGACAGTGCGGCGTCACAGAGCTCGAACAACGCATCCCGGGGGCCGAAGCCACCGTTGCCCACGGTGGTGTAGAGCGCGGCGAGGAGCGGGTGCAGGCGGAAACCCAACTGTTGCTCTGCCGCGTCGAGGCGCTGCAGGGCGACCGGGTCCCGCAAGTTCTCACTCTCCGCGGCGGCAGAGCGGACGCGTTGCAACAGCAGATCGAAATCGTTCACTCCGAAATTCTCCCGAACCCCACTGACATACCTGCCGGACGGCCCCTACCTGATGACCAACCAGACAGGATCATGGGACATCTGGCATCACCCACCGTCACCACGCCACGGAAGTTGAGCCAGAACCGCAACTCGTGAACAGAGCCACGGGAGCTGACCTCAGCTCAGTTGAGCCTCTGCTTGGTCTGGATGTTCGTGACACACGAAGCAGCTTCCAGGGCCGTGCGGAGCTGTTCGTTGGTCAACGCCAGTTGCTGGAGCTGGGCGATGGCGAGCGCGAGGTCTGTCGCCAGCTCACGGTTTCGCCGACGGAGCTTCGCGTTGCGCGCCACCAACTTGTCGTGGGCAGTCGGCCCTTCCGCGGGATCGGCGGGAGCGGACCGAACACGGCCGAGCTCGCTGGCGATGTCGGGGAAGCGGCGGCGGAACGTGGTGTTGCTCAGGCCAAGCTGGCGGGCGAGCTTCAGGACACTGGGCCTGGTGTTCGCCTGCTGGCATGACTCGATCATCTCCATCATCCGTTTGCGGACCAGGGCCTCGGGCAGGTCACAGGTGTTCGCGGTCATTCAGGGCTCTCCGTGCGCGTGTTGGCGGCCAGGAACTCGGTGATTTCGGCGTGGCGCTGTTGGAGCCGGTGCAATCGGAGCGGAGGCATGGCCGGCCGCATCGCCATCCTCTGCTCCAGGCGGACCAGCACGCGGGTCCAAGCCGCGACGTTCACCGGAGTGAGAGCAACATTTCTGCAGGCCAGGGGCTTGCAGCCGCCATGGTCGGGCAGTCCGTCACTTCCGCCGCGTTTCGCCTTGTCGCAGAGCGCCTTCGCCGGGTCGTGGACGCAGGTGACGTAGTCGCCGAAGTAGACCGCGGGATCATGCCGCATGATCCGCTTCAGGCGGTGTTTGTCCAGCGCGAGTTGGCCCTGGAACTGGGCTCGTTCGCCGAAGTCCGCGAGCCGCCTGGCGGCTTCTTCGGCCGACGGCCCGGTCAGGTCCAGGTGCTCGTGGGCGTCGATCATCGCAATGTAGGCCTCGCCCCGGGCTAGGGCCTGTTCGCTCTCTACTTCGGCCCGGAATCCAGAGGCGCTGGTGCCCAATGGTGGAGTCGGGTATTGGAACTGTCCGAATGCCTCAGCCATTGCGGACCCATGAGGTGAACTCGTCGGCGAGCCCCGATGGGTTGGCGACCTCGGTCCGCCGGGCGATCCCCTCGTAGTACTCCAACTCGTGGACGATCACTGGCACGGGTCAGCCGAGCGATCTCTCGATGACGCCGGTCCCGTGACGACCTCGGGCAAGCTGGCAGCAGGCTTGGTTGAAGTGAGCTTCGATCCCCGCGGCGAGCTAACCCCGGCTGCTGCCGCCCAGGGCCCGGCCAACAGCGCGGTTGCGAGCTGGTCGGACACCTACGGAGCGCAGTAGTCGCCCCAGTCCCGAGTGCCCGCGGCACACTCGAAGAGCTCCCGGAAGGTCGGGAAGAACATCTGGTCGCCCTCGCCGGTCCACAGGAACCTGCCCTTGCCTGTTTCGGCCGGGATCATGAAGATCGCGCGCGAGGCGTCCTCGTTGACCGAGACCGGAGCCAGAGCCACATCCGGCGCAAGGCCAGCGTCGACGCAGAACTCACCCTGCATCATGTCCCGAAACTCACGAGCGCCCTGCGGGGGCTCTCCGCCAGCCCAGTCCTGCCAGCCCAGCACCGGCATATTCAGGTAGAAGTGCTCCATGCCGTCGCTCTGCAGAAGGAACTCCGCATAGTCGGCGTCCAGGGGCTGGCCCATCCACCCCTCAAGCTCGATCAACTGTTCAGGCGTCGCGGGCGAGCGAAGGCCCGGAGGCGGTGACATCCACGGGTCCGAGTCGGCCATGTGCTCCCGCGACCGCCGGTCAACCACGTTGAACACCCAGTCGCTCATCATGCTTCGCCCTACCTCGCTTCGACACCCAGCCACCGAGCATTCTCTCCCCGGCGATATCCAGACGTATCAGCAGGGCCGGAACGGCGACTCGCATAGAAGCAGGCTCCTCCGGCCCGGGCCTCTCGGGGGCCAGCCCAGAAGAGCTCGGGACCTTCAGCCGCTATTGCCAATGGTGAGGGCGGGCTGACGTGGGCCGTCGTCCTCATTTTCGGTGAGGACGGAGACACGTAGATGTCGTCGGCCCCGCACGCCGGGATGGACGCGAGGGCGTTCCCAGCGAGAGGTGCTGAAGGTGATCGCGGAAGGTCATGGGCGGGCGGCTCCTGTCGGTCTGATCACGAGTCCCACTCGTCGCAGTACTCGATGTGGATCTCGCGTGCGTCGCCGAGAATGCCGTCGTTGGAGTGGAGCTCCGTGCAGAAGTGCGGGTAGCTCGGATGGACGGGGACGTAGCTGGGACCGTTTCGGGCGACGTTGAGGAAGTGCCGGGCGGTTTCCCTGAACACCTTCGCGCTGCCGGTCATGAACAGGGTCTCGGCGTGGAGATGCTGGTGGAACAGGTCCCGGTTCTCCCGGTAGTGCCGTGCCTCGTGGTCAATCACGGCTTCGCCTGTACGTCCTGAGGCGGGCAGCGTGACGGTCCGCGGGCGCCCGGGGCCGAGTCGCCCGCGTACTTCTTTCCATCGAGAAGGCGCGAACTGGAGCGAGTGATGCAGCAGCACGAGATCCAGCCGACGCGTGCCGTCTTCTGGAAACTCCCGGGAGGGGGGCCGGTTGCCTCGCATTGGCAGGTGGATCAGTGAGCGCGGTGAAGTGGCAGCGAGTCTCCATAGGCCGCCGATTCGTCGCGCGGCGTCTTGATCGAGATAGGCATCCAGGTGTCGATCGTGATCGGCGAGCACGGCGTGGACCAATGGCCGGGCTGGTCGGATGACTTTGAACTCCACGGCTCCGAGCCGTACTTGGTGGATAGTGATGGGTAGCTTCATCGCTTCTCCGGGACACGGCGGCTGACGTCGGCGGCGTAGGCGGCCCAGTCGCCGGCGGATGCCTTCTGCCACTGAACGGCGACTTGGATGTGGACGCCGAGCATCCGGGCGAGGATCGCGGCGGGGACTCCGGTGGCGAGGGTGAACAGCGCGGCGGAGCGGTCCTCCCTCGGCTGGAGGCCGATCTTCTGCAGGCGGATGCCGAGTTGGGAGTCACCGATCGGCTGTCCGGGGTGGCCGCCGGGGAACAGCCAGGGCACGTCGGCCGGGGTTCCGATCTTGGCCTTGCCCCGGCGGGTCGCTATGAGCTCACGGACGAGACCGGCCAGCGGCTCGGGTAGGACGACCGGGGAGGTGCCGAGCGTGATCTCGACCCGGTCCTCGCCCAGGCGGACATGGTCGACGGTGAGGCGGCTGATGGTGGCGATGCGCTGGGCATAGAGGACCAGCAGGAGGCCGGCGACGCGGTCTCGGGTCTGCAGGGTGTCGTCGTGCAGGAGCCGGCGGGCGTCGTCCCAGCGCTTCTCGGTGTCCAGCGCTCCCGTGGGGCCGGTCCAACGGACGGCACCGAAGGTCAGGTCTCGGGCGTGCCGGTGCCGGACCGCCCAGCGAACGAAGGCGGCGGTCTCGCCGCGGTAGCTGAAGTTCGGGTCGGCGATCCAGCGTTCCAGGTCGGGTTGGGTGCAGGTGTTCAGCGTCAGTTCGCTGTCGGCAAGCCAGGTAAGGAAGTTGGCCGCCGCGGTGACGTGGCAGCGGACGTTCAGGGCCTGAAGGTGGGAGGTGTGTTCTTGGCCGAGGCGCTGGCGGAGTCTTCGCAGGTGGTGCCAGACCGCGTAGCCGTGCAGGGTCCGGCGTTCGTCCGGGTTGGTGCGAGCCCCGACCGCTGAGGCGATCCAGCGTTCCAGGGTGACGAGGCGTTCGTCGCGGGGCGGCAGGGCGCCGGTGGCGACCAGGACGCTGCGGAGGTGGGCGAGGGTCTTGTCGCCGGGTAGTTCGTCGAGGGTCTCGTGGGTGACGGGGCGGTTGTCGCGGCCTATCTGTTCCAACAGGTCGCGGGCCTTGGAACGGGCTATCCAGGCCAGGGCGATGTCGGGGCGCATGGCGTCGACCAACGCTGCGTGGAAGGGGGTGAGGTCGCTTCTGACGGTTCCGTTGCCGTTGCCGAGGAGAGCGCGTACTTGCTGGTCAAGGATGCAGCGCTGGCAGGGGCGGGGGCTGAGCTGCCACGTCGTTTCGCAGGCCGGGCAGCGGCCCCATGCCTCGGGGTCGGGGTTGGTGCACCTCGCGCAGAGCGGTGCGTCCCAGGTTCCGCTACGGGCCTGGGCGACGGTCTCGCAGCCGCTGCAGGTCACCCAGCGGTGCTGGCAGCGCTCGCACCAGGGCTCGCCGGTGGCGCGCGAGACCTCGCAGGGCACCGTCCGTCCGCAGATCGCGCATTCGGTGGGTGTCCTGGGTCGGCACTTCTCGCAGTACGGCCCCTCGGGCAGTCGCGTTGCCACCCGCTTGCGCTGCCCGCAACCCGTGCAGCCTTCCGGGTTGATCGGCTCGCTGACCAGGCAGTTGGGACACAGCGGGCCCCCGTGCTCGTCTCTTGCGGCGGGCTCGCGCACCGATCCGCAGCGAGAGCAGGGCACGGCCGCGTGGCGGGCGAAACAGGCCCGGCAGACGCGCTCGCCGTCCAGAAGCTTGGAGAGCGCCTTCACTCCGTGGCAGCGAGGGCAGGCCGGCTTGACGACCTTCGACGCCCCGGCCGCGATGAGCTCGTCGATGAAACGCAGCACGGCCGGGACCGGGGCCTGGTGGCCGGCGCTGGTCAGCAGGTCCGGTTGGGCGACCACGGCCCAGGCCAGACGCCGCTGCCCGGCGGGGCGGACGGTGGCCCGGCCCAGTGCCGTCAGGACCGCGTCCGCGTCGAGCGCGGGGTCAATACTGGTGACGACCCCGGTGAGCTCATTCATCGGATCGCCCGCGTCGTCTGGGCAGTTGGCGCATCGGGGGTCTCCCTGGCGGTCCCGGCTGACGACCCGCCGGGTCTCACCGCAGCCCGCGCAGAGAGCTGGCTTGTCGAAGCAGGGCGAGCATCCCCACTGGCCACCGCTTCGACTGCCGACGTAGGGCCGTGCACGCCCGCATTCGCCGCAGCAAGGCAGAGCGATGTTCTGGGCGCCGGCTTCGTTCAGGGCCATCAGCAGCTTGGCGAGGCAGAACGGAGCCGGCGGGCGGCCGGTCCGCAGCAGCGACGGGTCGTCCCGCAGGGCCAGTGCCAGGCTGCGGCGGCCGGCCCGTCCGCGTACGACTGCGCAGACGATTTGGCGGACCCGTTCGGCATCCAGGTGCCGCTCGACGTTCCCAACCAGCCGCACGACCAGGCCGACCGGATCCACCAGAGCCTCGTCGAGGGCGTCGGTCACTGGTCCACCGGGGCGATCCTGGCCCGCTTGGGCCGCAGTTCGCCGATGCTCTCGGCAGCTGTGCCGCCAGCGGCGGCCTTCTTCGGCCTCTGCGCGGCGCCGGCCGCGGCGACGGGTTCGATCAGGTCGTCCATCGTGCAGTCCAGGATGTCCAAAAGGGCCATCAGGATCTTCAGGCTGAGGCGCTCGGGGCGCTCGACGACGAGCCGGTAGACCTGGCTGGAGGACAGGTTGATGCCGCGCTGGGCCAGCGACGGCAGGAGGTCAGTGGTGGAGAACATGCCGTGGTCCGCCATCAGGTGACGCAGGTGCCAGCGGTAGTCGAGCTTGGCGGCCAGGTCACGTCCGCTGGGGTGGTGTATCGCTGGCCACTCGGTGATCCGGCTTTAGGCTATGCGGTGAGTGCGGTCGGGGCGGCCTCGTCGGGGGTTTCTCCCTCGATCGGGTGGAGGCGGCAGCGGCCGAGGATCTCTGAGCCGATGTAGCGGCGCTGTTCGGCCCATTCGTCGCTCTGCTCGGCCAGGACCGCGCCGATCAGACGGACGATCGAGGCGCGGTCGGGGAAGATCCCGACGACGTCGGTGCGGCGCCGGATCTCCTTGTTCAGCCGTTCCTGCGGGTTGTTCGACCAGATCGACTTCCAGACCGTGCGCGGGAACACGGCGAAGGCCAGCAGGTCCTCGCGGGCATGCTCCAAGTGCTCCGCAGCCTTGGGGAATCGCTCGTCGAGAGCGGCGATAACGGAGGCCATCTGCTGACGCACGGCCTTCGCGTCAGGCTGTTCGAAGACGGTCCGCAGCAGGGTCGCGACCCAGGGCTGGGCCGACTTCGGGACCTGCGAGAGCAGATTTCGCGCGTAATGCGTCCGGCACCTCTGCCACGCGGCCCCGGGCAGGGTCGCACCGACCGCGTCCACCAGGCCGCCGTGGGCGTCGGAGACGACGAGCTGGACACCTCCCAGGCCGCGGGCGACCAGCGACCGCAGGAAGGCAAGCCAGCCGGCGCCGTCCTCGCTGGTGGCGACGTCCAGGCCGAGGACCTCACGCTGTCCCTCGTTGTTGACGCCGACCGCGACCAGGCAGTGCACGTTGACCACACGGCCGCCCTCGCGGACCTTCTGCGTGAGCGCGTCGACCCACACGAACGTGTAGGGGCCCTGGTCGAGGGGGCGGTTGCGGAACTCGGCCACCCGCTCGTCCAGATGCTTGGCCATCTCGCTGACCTGGGACTTCGACAGCTGGGTGACGCCCATGGTCTCGGCAAGCTTCTCCACCCGGCGGGTCGACACCCCGAGCAGGTAGCAGGTCGCGACCACCGAGATCAGGGCCTGCTCGGCCCGGCGCCGGCGCTCCAGCAGCCAGGACGGGAAGTACGAGCCCGAGCGGACGCGCGGGATCGCCAGGTCGACCGTGCCGACACGGGTGTCCCAGTCCCGGTTGCGGTATCCGTTGCGGGAGTTGACCCGGTCCTCGCCCGGGCGGCCGTACTCGCCGCCGCAGACGCGGTCCACGTCCGCGGACATCATCGCCTCCGCGAACGTCTTCACCATCGCCCGCAACAAGTCGGGACTCGCCGAAGCGAGGTTCTCCTCCAGCAGGGCAGCAAAGGGCACACTGTCACGTGCGGTCATCGTGCAGATCTCCTTCAAGAGCTTGGTCGTTCTCGAAGGATCAGCCGGTGGCCGTTTCACGTTCCCGGGCGACACCCACTACCGGGACGAAACCCCCGAAACGGATGGAACCCGTACACCACTTCTCTGGACGCAACCGGCGGCCATCATCGGTCCTTCCCGGTCGGCGCCTCGTCGAACGCCGGAATGTGTGACATATGAATGTCTGAGGGAATGGGGAACCAGAGCCTTGGGGAGCTTAAGGGCGTCGCGGTAGGCGACGAACCGGGCGTTGATCTCGGAGGGCTTGACGCGGCCGCCGCGTTCGGTCACCCACAGTGCAGGGTGGTCCTCGCAGCCGAAGCGTGGGCGGACGTTCTCCACGTAGTCCTGGGCGGCGTCCACTGCCCAGTCCATGACCGACAGCACGTTCCGGCGTCGCGGCGGCTGCCCCCGTTTCGCCTTGCCGTAGCGCACGTTGAGCGTTCCGTACCGGCCGAACTGACGTGCCTTCGGATTGCGTCCGAAGTCGACCACGTCCAGCGTTGAGTGCGTTAGTGGCTGTTGTCGTTCGGATCTTGAGGGGCGCTGGTCGAACGGAGTCTCGGCCGAGGTGCCACAGCAAGACGGCTCTGGCAGCCGGATTGTCACGCTCTCGGAGCACGCGGGGAGTTTTGGGGAGCGACGAGTGCGGAGCGTGGTCGAATACCTGAGTGCGGTCGGGCGTGGATCCCGGCAGGATGGGCGGATGGAGCAACCTCTTGATGTGCCCGAACTCGCTGCGGGTGAAGGTTTCACACTGCGACCGTGGCGGTTGTCGGACCTTGACCTCGTCCGTGAAGCGGCAGAGGACGATCACATTCCGTTGATCACGACGGTGCCTTCGCTGTTCTCCGACGCGGAGGGCGTCGCGTTCGTCGAGCGGCAGTGGGAGCGGGCCACCACCAGGGCTGGGTACTCGTTCGTCATCGTCAATCCTGCCGGTGAGCCGGTCGGCAACATGGGGCTGTGGCTCAAGGACCTGGGGCAGGGCCGCGCGTCACTTGGCTACTGGGTCGTCAAGTCAGCCCGAGGTCGGGGTGCTGCCGGGATCGCGCTCGAGGCAGTTGCCGGCTGGGCTCGGCGGGAACTGCGCATTCCCCGGCTGGAGCTCTATGTGGAGCCGTGGAACAGCGCTTCCATGCGGACCGCAGAGCGCGTCGGTTTCCAACGCGAGGGCCTGATGAGGAGCTGGCAGCAGGTCGGGGCCGAGCGTCGGGACATGTTCATGTACTCGCTGCTGAGCGACGGGCAGTGACGCCCCTGGTCCAGCCGTCGCATCGGCGGGACCAGGGTGATCGGTGAGGGCAAGCGTGCCGGGCGTGAGTCTCGATCGGGTGGTTGTGACGGGCGCTGTGCATGAGAGCAGACGCCTCAGGTAGCTCGGAGGGTGTCGAAGTCAATCTTCCGGGAGGCCCTGTTGCCGCATTCCTACGGCGGCGCCGCGGCGGGGTCCAGTTCGGCCACCCTGGCGTGTGACTGTCTGGCTCACCGATTCGGGAACGCCGGCGACCACGGGATGCGCGAACGCCGCTACCCGACCGACATGTCCAACGTCGAGTGGGCGCTGGCACGGCCGTTGCTGCCCGTGCCGGGTTGGCTACGCGGCCGGGGCGGCCAGCCTGAAGCCTACTGCCACCGAGCGATATTGGACGCGATCCGCTACCTGGTCGACAACGGCACGAAGTGGAGGGCCATCCCGGGCGACTTCCCGCCGTGGGATCGGGTCTACGCGTTCTTCCGGCGCTGGCGCGACCACGGCCTGGTCCGAGAGTTCCACGATCGGCTCCGCCGCCGAGTGCGCGAGCAGGCCGGGCGGGATCCGGAGCCGAGCGCGGGCGTGATCGACTCCCAGTCGGTCAAGGCCGACGCCGTCGTCGGCGCAGACAGCCGCGGCTTCGACGGCGGCAAGTTGATCAATGGCCGCAAGCGGCACGTCGTGGTCGACACCCTCGGCCTGCTGCTCGCGGTGATGGTCACCGCCGCGGACGTCGGCGACCGAGCCGCCGCCCAGAAGCTGCTCGCCCAGGTCGCGGCCGCGCACCACTGGCTGGCCCTGGTCTGGGCCGACGGCGGCTATACCGGCAGCCTCGTCGAGTACAGCCTCGCGGTCCTCTCCGTAGTCCTCGCAATCGTCAGGCGCAGCGACGACATGCGCGGTTTCGTGGTGCTGCCGAAGAGGTGGATCGTGGAGAGGTGCTTCGCTCACTTGATGCGAAGCCGCCGCCTCGTGCGCGACTTCGAGCGCTCCACCGGCAGCGCGGAGGCGATGGTCTACTGGTCGATGACGACGCTCATGACCCGGCGCCTTGCCCAGCCACGTCCTTCGCGAGCGTGA

Protein sequences of DBSCAN-SWA_4

>NZ_CP025394|8433009:8474425|8468024_8470439_-|WP_104820189.1|integrase|DBSCAN-SWA
MTDALDEALVDPVGLVVRLVGNVERHLDAERVRQIVCAVVRGRAGRRSLALALRDDPSLLRTGRPPAPFCLAKLLMALNEAGAQNIALPCCGECGRARPYVGSRSGGQWGCSPCFDKPALCAGCGETRRVVSRDRQGDPRCANCPDDAGDPMNELTGVVTSIDPALDADAVLTALGRATVRPAGQRRLAWAVVAQPDLLTSAGHQAPVPAVLRFIDELIAAGASKVVKPACPRCHGVKALSKLLDGERVCRACFARHAAVPCSRCGSVREPAARDEHGGPLCPNCLVSEPINPEGCTGCGQRKRVATRLPEGPYCEKCRPRTPTECAICGRTVPCEVSRATGEPWCERCQHRWVTCSGCETVAQARSGTWDAPLCARCTNPDPEAWGRCPACETTWQLSPRPCQRCILDQQVRALLGNGNGTVRSDLTPFHAALVDAMRPDIALAWIARSKARDLLEQIGRDNRPVTHETLDELPGDKTLAHLRSVLVATGALPPRDERLVTLERWIASAVGARTNPDERRTLHGYAVWHHLRRLRQRLGQEHTSHLQALNVRCHVTAAANFLTWLADSELTLNTCTQPDLERWIADPNFSYRGETAAFVRWAVRHRHARDLTFGAVRWTGPTGALDTEKRWDDARRLLHDDTLQTRDRVAGLLLVLYAQRIATISRLTVDHVRLGEDRVEITLGTSPVVLPEPLAGLVRELIATRRGKAKIGTPADVPWLFPGGHPGQPIGDSQLGIRLQKIGLQPREDRSAALFTLATGVPAAILARMLGVHIQVAVQWQKASAGDWAAYAADVSRRVPEKR
>NZ_CP025394|8433009:8474425|8463280_8463577_-|WP_174805603.1|DBSCAN-SWA
MPADQTDDSFMNHPNPGSWDPIRLFRSLVGSIHLAPGTLDLYIHSVSTLLLLHPWLPHAAPDTALTFYELAAELHDGSLISATSRRDLERLRYGRTGN
>NZ_CP025394|8433009:8474425|8435133_8436804_-|WP_104820169.1|DBSCAN-SWA
MNRRSFLSTAATVAGAAAMAPLLSACGDGGGRKAAANTAAGLKSALPTYLANAGAVKPDIAPVAGGADAATDPAYLSYPAHPPTSVSGVPGKGGSYTAVTPLWGTNPPAGNSFFQAMDKALGIELTVKPADGNTYDTIVPTMTAAKKLPDWINLPAWWNAKFNTGSLVGAQLADLTPYLSGDWIKKYPNLAALPTGAWQDGVWGDRLYGIPCFSTSFGIPGATFYRRDVLEARGITPDQIRSADDLMHLGKELTDAKRGVWAFDDVWTYLQTAWNVPMNWRIEGGKLVHPFETQEFLEALDWHYRLATSGFMHPDALAGDNANGNTRFYSGKTLIGGGGLGAWNLADHQSGTAADPKYRRGALDALTADGKGTPVIYMGASSSMISYLNAALKPAQIEELLGVADYLAAPYGTAEYTLVNFGVEGVHHTRVNGVPTFTEEGKKDVQATALPFLAAPASVISNPGGDQVTKDYAAWSAANVKYLTKPPFWGMNFSMPQAISVADAAQSVNDTLKDCYHGKKKVSDVQAAIAAWRSGPGERLKQWMTTEVLDKYGAGR
>NZ_CP025394|8433009:8474425|8444918_8446484_+|WP_168219651.1|DBSCAN-SWA
MTTRSWLRRVRRAVPAALSTALLVAGLLTGAAGAVEAAPPVTAGQGPCDIYAAGGTPCVAAHSTTRALLASYSGPLYQVQRASDGTVQDIGVLSAGGVSDAAAQDSFCAGTTCTITRVYDQTGGGNTLVYQGPGGTGGADTAATANTEPLIVAGHKAYALYINPGNSYFAYNSAGGVPTGSAPEGEYMVTSGTHVNKGCCFDYGNTETDHKADGNGAMDAINFGTECWFGGCTGTAPWVQADLENGLFSGGSKAWNPGQVSLPSRFVTAMLKNDGTTRMALKGADAQSGSLTQLYGGALPGGWSPMHKQGAVILGSGGDCCQTNHNASAGTFYEGAMVKGYPSDATDAAVQADITAAGYRTATPFTPGAKVSLQATTACCTGDYLQHDSGDDKVVTAPVTAAGSAAAKGAATWTVRAGLANSSCVSFESADTPGSYLRHYAFQLHLQPNAGTGQFAADATFCVQPGNSGTGYSLQSFNYPAKYVRHYGFVGYLASNGGTNVWDNASSWAQDSSWLAAQPWG
>NZ_CP025394|8433009:8474425|8465686_8466139_-|WP_174805604.1|DBSCAN-SWA
MIDAHEHLDLTGPSAEEAARRLADFGERAQFQGQLALDKHRLKRIMRHDPAVYFGDYVTCVHDPAKALCDKAKRGGSDGLPDHGGCKPLACRNVALTPVNVAAWTRVLVRLEQRMAMRPAMPPLRLHRLQQRHAEITEFLAANTRTESPE
>NZ_CP025394|8433009:8474425|8461262_8461940_+|WP_104820183.1|DBSCAN-SWA
MTTATARFTPGSTAVRRDVHHGRVWSAQPYRTLTDDGDVLELLYWPGLTSLGPTTWSDAMRTGDHALRQSGLQDLAAGNWQLGPWTWEKTALRSRLESGAYFSIHTFQDAATGEPLRWYVNFELPYTRTPIGLDTFDLFVDLVVEPDLSAHHWKDVDEYEQARHLGLIDDDLHVQVEAAREQALGLLQDRRGPFAEAWPTWAPDPGWPHPQLPCDAGDYETGRAR
>NZ_CP025394|8433009:8474425|8470435_8470777_-|WP_174805681.1|DBSCAN-SWA
MAAKLDYRWHLRHLMADHGMFSTTDLLPSLAQRGINLSSSQVYRLVVERPERLSLKILMALLDILDCTMDDLIEPVAAAGAAQRPKKAAAGGTAAESIGELRPKRARIAPVDQ
>NZ_CP025394|8433009:8474425|8446643_8448626_+|WP_104820172.1|DBSCAN-SWA
MSYSIRAGAVERHTAAEVLRVEPWGPDAVRVRASSGAIDPAAPGALIPPPSGPPSEASVSQDGSARLVNGCIAVEASADGRLRFCHAVSGRELLAERSPHAHHTGPRVHATAGRTAQSFEAYEGERLHGLGQHLHGRLDQKGCVIDLVQANTVAAVPFLHSSRGYGLLWNNPATGRVELGADTTRWTADAGGRIDYWITAGDTPARILDSYTRATGRPPLLPEWASGFWQSKLRYRTQDELLTVARQYKERGLPLSVIVCDFFHWPRMGDWRFEQSEWPDPTAMVKELSALGVKLAVSVWPTVEPGSDAFDGLRSAGHLVRDSAGGLLTHPWPSRYGGEALIRPMAHYDATHPGARAALWRRLDENYRSLGVACFWLDACEPDLPPGLAERAVYAAGPAAEVANLYPLEHTRAVAEGLRAAGEERPLSLVRSAWAGSQAHGALLWSGDIPTTFDSLGRQIRAGLNVAMSGIPWWNTDIGGFSGGDPDDPGYRELLVRWFQYGTFCPVMRLHGDRAPNYPTFSTDMTGGPNEVWSYGEQAYGILRDHLLLRERLRPYLRTLSEDAHRTGAPPMRPLFFAFPEDERAWAVDDQFLLGPDLLVAPVYQAGVRARRVYLPVGARWVDPVTGSAREGGTTVDAEAPLERIPVFVRHGAEVAAVFG
>NZ_CP025394|8433009:8474425|8452363_8453146_-|WP_104820174.1|DBSCAN-SWA
MDTALAHLDDPPVVAAVGIGVHGCAGRTDVFLLPDLWQLHLYGYEAELTVDGTAHAIRPGRVSLVPPGTTVRYRYRGRSEHLYVHLRLGTAGPQIGIPVIQDTGTELAPLRAQLTSALAAWPHSPVRATAEVWAALWRVAQLAPLRTADTAAPHPAVAAALAMIEARLAEPLSVAELARAAGVSHNHLTRLFRAATGATVVGYLRARRMARARHFLQATTLSIPAIAASVGIPDLQAFNKACRRDLGASPRAVRAGLNTG
>NZ_CP025394|8433009:8474425|8453865_8454636_-|WP_104820176.1|DBSCAN-SWA
MTAIAPLGRRAAAEFVGTGALVAVVVGSGIQAAQLSGDVGVQLLANSLTTVFGLGVLILLLGPVSGAHFNPAVTLAAWWTGRDGDGPGLREVAAYVGAQVAGAIGGAVLADAMFAKTPVAWSTHDRWAPHLWLGEVVATTGLILLIFGLARVGRERFAPVAVASFIGAAYWFTSSTSFANPAVTIGRAFTDTFAGVAPASVLPFIAAQLAGLAAGLGLVAVLFGRPSPAVAEHDTEHVAEHVVVPHGDHEPAPAGR
>NZ_CP025394|8433009:8474425|8455360_8456155_+|WP_174805680.1|transposase|DBSCAN-SWA
MWSHLCRWEDLLVPVSRTAGRQGLALGEGWTRRWTVTWRHRSGEVTGAVASLGQAPWVGCVPMRGFAWRRDQRHRPGLEYLVSTGRLHGFESLEEDWLLRALDFCGGVQILLSQPFRMRFEANRRLRRHTPDYLVVSDDGVFVVDVRPAGLIKSEDEESFAAAHELSLASGWRYVVAAGWSPHVQASLDAMYARRRPMSDPLNLRPELLAAAEQGVTFREAAMACQFWPVARAQLLHLLWQRRLGVDLSEPLTDASRLMPAEVS
>NZ_CP025394|8433009:8474425|8473633_8474425_+|WP_104821379.1|transposase|DBSCAN-SWA
MSNVEWALARPLLPVPGWLRGRGGQPEAYCHRAILDAIRYLVDNGTKWRAIPGDFPPWDRVYAFFRRWRDHGLVREFHDRLRRRVREQAGRDPEPSAGVIDSQSVKADAVVGADSRGFDGGKLINGRKRHVVVDTLGLLLAVMVTAADVGDRAAAQKLLAQVAAAHHWLALVWADGGYTGSLVEYSLAVLSVVLAIVRRSDDMRGFVVLPKRWIVERCFAHLMRSRRLVRDFERSTGSAEAMVYWSMTTLMTRRLAQPRPSRA
>NZ_CP025394|8433009:8474425|8462567_8463260_-|WP_104820184.1|DBSCAN-SWA
MEHQLDDADAAGIAHLLFEAGSLRGLPRTGWRQDGIPLAITETVAEHSHRTSVIGATLATLEGADPARTTLLCTLHDLPETRTGDLTPLTKRYATTADPRKVLADQVTGTHPAVRDVFTEAVAEFEDGTTPEARCARDADKLDCLLRALEYRAGGVSAVQGKIDRCRAALVTVAACRIADAAVKLAPTDWQYRGALPTGGVAGLQHHPCVCPQQPRRLPSPQAESQWWCN
>NZ_CP025394|8433009:8474425|8434189_8435050_-|WP_104821372.1|DBSCAN-SWA
MTVPAVLLLLVFNYAPLFGIVTAFQDYDPLVGVWHSEWVGLDQFQQLFNDPAFWAALKNTLYLSFVQLVLFFPVPIALALLLDSVVSERIRNFFQSVVYLPHFFSWVLAVTIFQQMLGGAGALNQFLRQHSLATWDIMTNPHTFALLVTSQAIWKEAGWGIIVFLAALSAINGELYEAAAADGAGRLRRLWHITLPGLRGVIVLMLVLRLGNALSVGFEQFLIQREAVGHDAADVLDTFSFYYGIATGGYSFGAAAGLFKSVVSLLLIWGANKLAHAFGEDGLYRN
>NZ_CP025394|8433009:8474425|8463810_8464359_+|WP_104821378.1|DBSCAN-SWA
MTDDPFQCRCVLCHDYGDRDEADQVERTIIGNVQEHGWHVAMVPEDEIGPGFAYTIGLAHTHGTPELAMFGLDVHLMHRMLNTLGEKAASSTALADGQEHHGIARGLPVRLRRADLRWYRTFFGRAIGFYRRPPFPVLQVAWPDANGRFHWEEGVEPGHRDSQPQLWLSPGEHPAGVWTAEL
>NZ_CP025394|8433009:8474425|8464572_8465124_-|WP_104820185.1|DBSCAN-SWA
MNDFDLLLQRVRSAAAESENLRDPVALQRLDAAEQQLGFRLHPLLAALYTTVGNGGFGPRDALFELCDAALSDSMETALGNYTLASADHSDPVLSWPAGVLPILDWGCGMLACVDCRSADGTVLLFEPNALDGEDASTVWFVDSPSLAEWLRTWLDRRGWYEDDQMDETSDMRLWPEAANRLG
>NZ_CP025394|8433009:8474425|8437174_8439901_+|WP_104821373.1|DBSCAN-SWA
MLHQYAPAVPRLGVAAFRTGSEALHGVSWLGEATVFPQAVGLGASWDESLVREVAAAVSTELRAFHLHRPPAIGAAERGATSLQAWAPVLNLLRDPRWGRNEEGYSEDPVHTARIGEAYCRGLAGDHPVYLRTAPVLKHFLAYNNEDDRCTTSSGLRPRVLQEYDLAAFRPVVAAGAATGAMAAYNLVNGRPCHVSPLIETELRRWAAPTGHELFVVSDAEAPSNLVDPEHYFDDHAESHAAALKAGIDSFTDHGEDSETVVGRLREALERGLMAQQDVDRAVRRQLELRFRLGEFDPELDPYAGIGPEVVDCAEHRALARRAVAESTVLLKNEGLLPLDPARPPRIAVIGPLADSVFEDWYSGTLPYRIGLAGALAAAGVEVTRVDGSDRIALRSRTTGELLGKTAFDLTDWGGGAVTLRAADTGRYLGLQEDGGLAADRSVIKSWFVTETFRLEAVGPDEVVLRSVFTGRYAGVDPTDGRVSVHIETAAEAERWQRELVRDGLAEARAAAEAAEVAVVMLGNHPMINGRETEDRADIALPEGQEALLRAVAAARPETALVVTSSYPYALDWADEHLPAVVWTSHGGQEGGHALADVLLGAAEPAGRLPQTWYRGEDPLPHPLDYDVIKAGWTYQYHRTPARYAFGHGLSYTEFAYRDLRLSQPSIDQAGAVEAVVTLENTGERPGSEVVQVYLRAPEARYAAPRLSLAEFRKLRLEPGESRELTFRLTAGQLAHWDVATGAFTVDPGRYEVIVARSADHHELTAPLTVTGAAPAPRAGVGRCLLAVDFDDYEEAVIVDATRADGDAVTPADPARPATLLFREVDLSGAARVEVETAREGVGPGGARLELRSGGRLLAAIEVPVTGHRYAWTTTGAKLAAPLDGVHDLSLALHGDFRLAAFRFGAAG
>NZ_CP025394|8433009:8474425|8442500_8444783_+|WP_104820171.1|DBSCAN-SWA
MKFTDGYWLMRPGVTARYAAEVADLRAGADRMTLYAPVKPVRGRGDTLNSPLLTVECWSPAEGVIGVRTTHHAGSVRRGPDFALPGAVADAGKVRRDGTVAELSSGELTLRVDTAQPWRLEFGAGGRVLTSAGERGTGFVTDAEGRHHVLAQLALGVGESVYGLGERFTPFVRNGQVVDIWQADGGTSSEQAYKNVPFHLTNRGYGVFVNHPGRVSYEVGSEAVGQVQFSVEDQTLEYFVVYGPTPKQVLERYTALTGRPALPPAWALGLWLTTSFTTEYDEATVMRFVGGMAARGIPLSVFHFDCFWMREYQWSDFEWDPETFPDPAGILARLRQQGLRICLWINPYIAQKSALFEEGMRAGYLVRRADGTVWQWDLWQPGMALVDFTNPAAREWYTGRLRQLLGQGVDCFKTDFGERIPTDVVWHDGSDPERMHNYYTQLYNRAVFELLREVRGEGEAMLFARSATAGGQQYPVHWGGDCESHFNAMAESLRGGLSLGLSGFGFWSHDIGGFEGTPTPTVFKRWTQFGLLSSHSRLHGSKSYRVPWDFGEEAVAVTREFTLLKHRLAPYLQRAAQQAHTTGVPVMRAMVLEYPDDPAAATLDRQYLLGDDLLVAPVFTEDGTVDYYVPEGTWTNLLTGAQVTGPRWVREQHGFHTLPLLARPDSVIPLGADDQHPVSAWADGVELRVHAFADGAERTVLIPRSDGPGESARFRLRRTGDRLHVSTDSPHAWQLRTGGPDGPVHLGPPGTFEAELPFPV
>NZ_CP025394|8433009:8474425|8441097_8442504_+|WP_174805601.1|DBSCAN-SWA
MNAPAQLVRCLPAGFRFGAATAAYQIEGAHREDGRGPSVWDTFSHTPGRTLDGATGDTACDHYHRYPEDVALLRGLGVDGYRFSISWPRLLPQGTGPVNAKGLDFYDRLIDELLAAGVAPAVTLYHWDLPQALEDRGGWRVRATAEAFAAFAALAAERYGDRVERWITLNEPYCSAFVGYAEGRHAPGAREGRGALAAAHHLLVGHGLAVRELRAAGAREIGITLNLDRVHAASTLPEDLAARRRAKVLHNEVWTEPLFAGRYPPQERQTWGGLAGGPWRRPGDLELIGAPLDFLGVNFYRPITVAAAPHREADPERRTAVDIGVTELDPYGTRHTTMGWPVVPAAFTELLRELHRRHPRLPPIWITENGTAEADTVGADGLVHDAQRIDYLAEHLAAVAEAVAAGVDVRGYYLWSLLDNFEWARGYAQRFGLVHVDFDTLTRTPKDSYHWYRALIAAHRARTEEAAR
>NZ_CP025394|8433009:8474425|8472796_8473345_+|WP_104820191.1|DBSCAN-SWA
MEQPLDVPELAAGEGFTLRPWRLSDLDLVREAAEDDHIPLITTVPSLFSDAEGVAFVERQWERATTRAGYSFVIVNPAGEPVGNMGLWLKDLGQGRASLGYWVVKSARGRGAAGIALEAVAGWARRELRIPRLELYVEPWNSASMRTAERVGFQREGLMRSWQQVGAERRDMFMYSLLSDGQ
>NZ_CP025394|8433009:8474425|8448813_8450205_+|WP_158702552.1|DBSCAN-SWA
MPKPRLRQLLVRSLLVGALGTTAALGSTTAQAATPAVASPAAAAQATAGGGSFSVLTYNVAGLPQVLSSASTDRQSSTTAIGSRVAPYDVVNVQEDFNYHAALYATDTHPYRTATSGGAGIGSGLNTMSRFAYDGDDFERVHWHDCQLDSGDCLTPKGFTFMRTRLAEGVYVDFYNLHANAGTEPGDEAARAANLAQLTGYIQTHSAGNAVVVMGDTNTRYTRADDTIAAFAADNRLTDAWVQLERGGVPPVKGSDPLLCDQNAPTDTCEIVDKVLYRSSALVTLGATSYADKHVDFLDGAGKMLSDHDPVAVGFTWSQNPAYQASEQFGGPHGDFYNDIDRVPAGAQAAVVSLRSGSRVDQVGLTLADGTSLTHGGTGGTAASLTLGGGEYVNSATLCEGSYSGHTRIFYASFGTNLGRSLAGGTTTADCVTRTAPAGWQFAGFQGRSGDEVDKLGFLLTRR
>NZ_CP025394|8433009:8474425|8456151_8458410_+|WP_104820178.1|transposase|DBSCAN-SWA
MSAGALDLAPGAALVLDASEWLVERQEPHLGRVHLMNRAGVRQCVSFRFLLNHPQCRSSSLTSSSGANRGRQEMTLKDLKPEKVPLVELRFEHLMEVFCDFRSGDPLHPRPGDPRPEYHPDRTTVSERRQAKVAELDAMDPAAANLLALDRVGVRTLERWERKRRRFGVIGCADDRWLRESGGHPSISEEIREAILAVREETRLHRSRVDARTRETMIHRYVRETFPGQEIKVPSYDTLRRVWHEWFGPGRGGQRYERSASLPEKDGHGLVTRPGQAVALDTTIMPVMVREGVFGDPVRVHLTLALDVYTHSICAFRLTLVSDTSVDVAMVLRDVMLPLPMRADWDGEMEWPYPGLPAAVVAEFVGHRVAALPFFAPETVTTDHGSVYRNHHLVEVQEVIGCRVLPARVLRPQDKQAVERVFGSIRSLLFEHLPGYTGIDTADRGAEPERDGTLTIDAMEHVIATWVVKVWQNRRLGDYAPAWDPGGDHSPNSLFAASFAQTGFAMEIPQPELYYRFLPEHQVKRIHGRRGVKIKGLYYYGDALEPHLHEASSRGGRRKQMWIIRREPRDRRVVYFQGPVTHEWHPLRWTGLPPESQVPAFGDLRAEELLTRVREAGLRPRTDAELLPILLDLLGARDPVSNWPSQMTKSQRVEHAREATQAQAASTDRPAASAEPTPPTRQPQQTAGNVLQWPQRAGQTRGSLDAERRRRREATVPVTPKPPPRLGSSFRERNVFLLPEDDEEEHGGQPAG
>NZ_CP025394|8433009:8474425|8454632_8455010_-|WP_104820177.1|DBSCAN-SWA
MSNLELPVLGQDEPAACCSPMAREPLGEEAAADLAKMFKALSDPVRLRLLSLIASHEGGEACVCDLTGPFDVSQPTISHHLKVLREAGLVGSERRGTWVYYWVLPAALAKLSTLLQTPAGAGGAR
>NZ_CP025394|8433009:8474425|8467374_8468028_-|WP_104820188.1|DBSCAN-SWA
MKLPITIHQVRLGAVEFKVIRPARPLVHAVLADHDRHLDAYLDQDAARRIGGLWRLAATSPRSLIHLPMRGNRPPSREFPEDGTRRLDLVLLHHSLQFAPSRWKEVRGRLGPGRPRTVTLPASGRTGEAVIDHEARHYRENRDLFHQHLHAETLFMTGSAKVFRETARHFLNVARNGPSYVPVHPSYPHFCTELHSNDGILGDAREIHIEYCDEWDS
>NZ_CP025394|8433009:8474425|8453402_8453822_-|WP_174805602.1|DBSCAN-SWA
MSTPAVPSVLFVCVHNAGRSQMAAAFLTRLGGERVEVRSAGSAPAETVNPAVVEALAEVGIDISAETPKVLTVEAVQASDVVITMGCGDACPFFPGKTYLDWRLADPAGQGVAAVRPIRDEIEARIRGLLADLGIEPAA
>NZ_CP025394|8433009:8474425|8458390_8459395_+|WP_104820179.1|DBSCAN-SWA
MDNRPAESDSPIVPFLRVGPPPDRTRWEGWQQWREIRDTFIPAPRLSLKTWARLMAPPTNRSSSCQPGSVAVWLVSACTSSSSIMAWTASRVIGDWSWNCVMAAKPERGGAAFTVSLPPRSASSWLRRCRACSVSRASGMAARRWRAVVPWGIVPLSSRGLVAEAARCWAVLVCWGGTLLADVGERLGRERGLVEQPVLDECEAALVQPGECVVDHVGVAGGESGGCEGLFGGEGGVGHLPDGGVGIRVPCSRGDAQGLGQVSEDGTVVASDRGRLVGAVRERGVRLPVGCERAGAGGGAGGTGDRQDVMDERGWVLLGDLADDVPGRVAAGPE
>NZ_CP025394|8433009:8474425|8460440_8460650_+|WP_104820181.1|DBSCAN-SWA
MPGAGDACHPSAPVADISSLASDSLPDVRSQRLVRSLNDIADALRAHRTVPCVAEYLDTHHAAHLPPTA
>NZ_CP025394|8433009:8474425|8450288_8452310_+|WP_104820173.1|DBSCAN-SWA
MNDQPTLDRRRFLRSSAATSVALLTAPTALSLLTAPQRAVAAAPVGSVAGGSAAGHSGPVGPVSGPAFVDSYTTNTMADLTPTGNAAVRILTGMSRIWRTGGAWNDGSPLLAEVLRANVRSCVQATTQRTAEQAKEAFIYDRQHQSYAVIAGLGPLAELYRTGARAVTSITTAPDSTPPGKIDDAVPADAPAGSALGPGAVDSELGRVVTLVNTLRGPYASGNPAKYAYRYPRPWRLNGQSAVVDTGATDAFGFPVYASEVVVAPQLLRQRNASPADDGGFVSGHTNAFHLAALALAYAVPERFQELVTRAFELSHTRITAGMHSPLDVIGGRTLATALAAATLADPRNAALKAAARSQAAAYFQARTGSFQAKTESFQGKTGGTTDTLYAFAHRAGTAEDPYADRLANAALVRPKLTYVLRRGGREVPMTVPKGAEVLLETRLPYLDADQRREVLRTTALPSGYVLLDGPEMWGRLDLFAAADGYGSFERDVTVELDAAEGGFCAADAWRNDIGGPGGLTKRGTGTLTLTGTNRYTGTTVVAAGALVAGSHDALGRGDVQLRGGTLRVDAERGPVRVHGDYSQAGTGTCLELTAHQLHRAVLTVAGRLVLGHGARLALELREIGPLGEEAVLPVISGCAVQGGFGSVTVDVSGYRATPLRTREGISVRLTRC
>NZ_CP025394|8433009:8474425|8470830_8472069_-|WP_104815543.1|transposase|DBSCAN-SWA
MTARDSVPFAALLEENLASASPDLLRAMVKTFAEAMMSADVDRVCGGEYGRPGEDRVNSRNGYRNRDWDTRVGTVDLAIPRVRSGSYFPSWLLERRRRAEQALISVVATCYLLGVSTRRVEKLAETMGVTQLSKSQVSEMAKHLDERVAEFRNRPLDQGPYTFVWVDALTQKVREGGRVVNVHCLVAVGVNNEGQREVLGLDVATSEDGAGWLAFLRSLVARGLGGVQLVVSDAHGGLVDAVGATLPGAAWQRCRTHYARNLLSQVPKSAQPWVATLLRTVFEQPDAKAVRQQMASVIAALDERFPKAAEHLEHAREDLLAFAVFPRTVWKSIWSNNPQERLNKEIRRRTDVVGIFPDRASIVRLIGAVLAEQSDEWAEQRRYIGSEILGRCRLHPIEGETPDEAAPTALTA
>NZ_CP025394|8433009:8474425|8465288_8465690_-|WP_104820186.1|DBSCAN-SWA
MTANTCDLPEALVRKRMMEMIESCQQANTRPSVLKLARQLGLSNTTFRRRFPDIASELGRVRSAPADPAEGPTAHDKLVARNAKLRRRNRELATDLALAIAQLQQLALTNEQLRTALEAASCVTNIQTKQRLN
>NZ_CP025394|8433009:8474425|8433009_8434155_+|WP_104820168.1|transposase|DBSCAN-SWA
MHASTHVKRAYRYRFYPTDAQAAELSRTFGCVRKVYNMALQACTKAWALNQERVSYGATSAMLTQWKKTEDLAYLSEVSSVPLQQTLRHLQGAFTNFWQKRAKYPRFKSRKKSRKSAEYTRSAFRFRDGRLWLAKMAGRWFVSMLCDDRPAMPVPVSAAVGIDVGIISVVTLSTGEKITNPRQESKGRERLAKAQRDLARKAEGDGMNRAKARRRVARVHARVADRGRDFLHKLTTRLVRENQTIVIEDLTVRDILKNRRLSRVVSDASWTEMRSMLEYKTDWYGRELIVIDRWFPSSKLCSSCGTLQGRMQLDVREWTCGCGATHDRDVNAAINILAAGLAVAACGDGVRPQRSTPGGQSSMKQEVVPPPRSRAAGQSRG
>NZ_CP025394|8433009:8474425|8440099_8441101_+|WP_168219704.1|DBSCAN-SWA
MPPTDLGLDALADHKPEPAAPQDFDAFWQRTLAEARSHGGAVKVERVTERYGLRTVEVEDVRFPGWNGEPVAAWLLRPRGAEGPLRGVEGPLPVVVTYLGYSGGRGLPTEHLFWSAAGYAQLVVDSRGQGHDTPDRTVGDGTQWAEGFMTRGIDSPEHHYYRRLMTDCVRAVDAVGRLPGLDSGKVVVTGVSQGGGLALAVAGLTGDGVAAVLPDVPFLCHYRQGAQLSLEGPYQEIVKYLRWHSRHRVAETFATLGYFDGVHFARRATAPALFSVGGMDPVCPPPTVYAAFNHYRGADRTMTVWPFADHAGGCGSNPPVQLAWLRERGLGPA
>NZ_CP025394|8433009:8474425|8460658_8461204_+|WP_104820182.1|DBSCAN-SWA
MSPALALQRYGAGDTTDLLDTLADVWAEAHTGHHDVAAAGFTPDTLRRQITGHAHHDGFVLVAAYAEGQLVGFGYGFRCSPSYWYGEQLRPAITPDARDTDSLAGICELAVRTGWQGRGVGTGIHTALLEALRTEWVSLLAMPDNGPARQLYDRLGYRYAGPYSAGPDGPVLDLLLLRTPL
>NZ_CP025394|8433009:8474425|8459941_8460286_-|WP_104820180.1|DBSCAN-SWA
MDTDTVLAALALLRSRLQAETQATVTKHQTELVNSWTARHGESGLRVLLTSGVEKDQLLRGDPDGASERLASEEMRLFGGRPWPRQPCRTPVGPTSDIATSGRRLQKLTLRVTS
>NZ_CP025394|8433009:8474425|8466526_8467039_-|WP_104820187.1|DBSCAN-SWA
MMSDWVFNVVDRRSREHMADSDPWMSPPPGLRSPATPEQLIELEGWMGQPLDADYAEFLLQSDGMEHFYLNMPVLGWQDWAGGEPPQGAREFRDMMQGEFCVDAGLAPDVALAPVSVNEDASRAIFMIPAETGKGRFLWTGEGDQMFFPTFRELFECAAGTRDWGDYCAP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_104820168.1|8433009_8434155_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0R8V9X2	Thermobifida_phage	1.6e-121	64.7
WP_104821372.1|8434189_8435050_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_104820169.1|8435133_8436804_-	Tat pathway signal sequence domain protein	NA	NA	NA	NA
WP_104821373.1|8437174_8439901_+	glycoside hydrolase family 3 C-terminal domain-containing protein	NA	NA	NA	NA
WP_168219704.1|8440099_8441101_+	acetylxylan esterase	NA	NA	NA	NA
WP_174805601.1|8441097_8442504_+	beta-glucosidase	A0A0B5JD41	Pandoravirus	3.5e-73	38.2
WP_104820171.1|8442500_8444783_+	alpha-xylosidase	NA	NA	NA	NA
WP_168219651.1|8444918_8446484_+	AbfB domain-containing protein	NA	NA	NA	NA
WP_104820172.1|8446643_8448626_+	glycoside hydrolase family 31 protein	NA	NA	NA	NA
WP_158702552.1|8448813_8450205_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_104820173.1|8450288_8452310_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_104820174.1|8452363_8453146_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
8452440:8452457	attL	NA	NA	NA	NA
WP_174805602.1|8453402_8453822_-	arsenate reductase ArsC	A0A2H4PQT9	Staphylococcus_phage	1.0e-09	35.8
WP_104820176.1|8453865_8454636_-	aquaporin	NA	NA	NA	NA
WP_104820177.1|8454632_8455010_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_174805680.1|8455360_8456155_+|transposase	TnsA-like heteromeric transposase endonuclease subunit	NA	NA	NA	NA
WP_104820178.1|8456151_8458410_+|transposase	transposase	NA	NA	NA	NA
WP_104820179.1|8458390_8459395_+	hypothetical protein	NA	NA	NA	NA
WP_104820180.1|8459941_8460286_-	hypothetical protein	NA	NA	NA	NA
WP_104820181.1|8460440_8460650_+	hypothetical protein	NA	NA	NA	NA
WP_104820182.1|8460658_8461204_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_104820183.1|8461262_8461940_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_104820184.1|8462567_8463260_-	HD domain-containing protein	NA	NA	NA	NA
WP_174805603.1|8463280_8463577_-	hypothetical protein	NA	NA	NA	NA
WP_104821378.1|8463810_8464359_+	DUF4262 domain-containing protein	NA	NA	NA	NA
WP_104820185.1|8464572_8465124_-	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_104820186.1|8465288_8465690_-	hypothetical protein	NA	NA	NA	NA
WP_174805604.1|8465686_8466139_-	hypothetical protein	NA	NA	NA	NA
WP_104820187.1|8466526_8467039_-	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_104820188.1|8467374_8468028_-	hypothetical protein	NA	NA	NA	NA
WP_104820189.1|8468024_8470439_-|integrase	site-specific integrase	NA	NA	NA	NA
WP_174805681.1|8470435_8470777_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_104815543.1|8470830_8472069_-|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	8.3e-79	44.6
WP_104820191.1|8472796_8473345_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_104821379.1|8473633_8474425_+|transposase	IS5 family transposase	NA	NA	NA	NA
8474910:8474927	attR	NA	NA	NA	NA