CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP025318	Escherichia coli strain FORC_042 chromosome, complete genome	7 crisprs	csa3,cas3,cas8e,cse2gr11,cas5,cas6e,cas1,cas2,DEDDh,DinG,c2c9_V-U4	0	10	13	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP025318_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025318_1

622635-622752

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025318_1

>merge|NZ_CP025318|1|622635-622752|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>NZ_CP025318|1|1|622635-622752|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025318.1\|WP_000384145.1\|625363_625729_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP025318.1\|WP_000531201.1\|626021_627008_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223512
NZ_CP025318.1\|WP_000603618.1\|627077_627560_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP025318.1\|WP_001198780.1\|624765_625122_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP025318.1\|WP_000145820.1\|610351_610696_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP025318.1\|WP_000622115.1\|618299_619664_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP025318.1\|WP_000107720.1\|612931_614263_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP025318.1\|WP_000785722.1\|627944_628349_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP025318.1\|WP_001297162.1\|614288_615497_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP025318.1\|WP_000031415.1\|628351_628657_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP025318.1\|WP_104951010.1\|619938_621276_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP025318.1\|WP_001295544.1\|622825_622990_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025318.1\|WP_000548347.1\|611920_612910_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP025318.1\|WP_000096086.1\|627655_627955_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP025318.1\|WP_000460535.1\|621303_622614_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP025318.1\|WP_104951011.1\|623818_624715_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
NZ_CP025318.1\|WP_000719990.1\|617838_618228_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP025318.1\|WP_000104211.1\|610883_611822_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP025318.1\|WP_024215656.1\|623012_623714_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP025318.1\|WP_104951009.1\|615530_617825_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087

Protein	Function_ID	Function_description	E-value
NZ_CP025318.1\|WP_000384145.1\|625363_625729_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
NZ_CP025318.1\|WP_000531201.1\|626021_627008_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP025318.1\|WP_000603618.1\|627077_627560_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	1.8476e-29
NZ_CP025318.1\|WP_001198780.1\|624765_625122_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35
NZ_CP025318.1\|WP_000145820.1\|610351_610696_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	3.36123e-66
NZ_CP025318.1\|WP_000622115.1\|618299_619664_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP025318.1\|WP_000107720.1\|612931_614263_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP025318.1\|WP_000785722.1\|627944_628349_-\|hypothetical-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP025318.1\|WP_001297162.1\|614288_615497_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP025318.1\|WP_000031415.1\|628351_628657_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP025318.1\|WP_104951010.1\|619938_621276_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	8.99641e-168
NZ_CP025318.1\|WP_000548347.1\|611920_612910_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP025318.1\|WP_000096086.1\|627655_627955_-\|hypothetical-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP025318.1\|WP_000460535.1\|621303_622614_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0
NZ_CP025318.1\|WP_104951011.1\|623818_624715_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.27172e-52
NZ_CP025318.1\|WP_000719990.1\|617838_618228_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP025318.1\|WP_000104211.1\|610883_611822_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP025318.1\|WP_024215656.1\|623012_623714_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	2.76414e-67
NZ_CP025318.1\|WP_104951009.1\|615530_617825_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0

>NZ_CP025318.1|WP_000460535.1|621303_622614_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDSTAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWHGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP025318.1|WP_104951010.1|619938_621276_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP025318.1|WP_000622115.1|618299_619664_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP025318.1|WP_000719990.1|617838_618228_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP025318.1|WP_104951009.1|615530_617825_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDECVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP025318.1|WP_001297162.1|614288_615497_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP025318.1|WP_000107720.1|612931_614263_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP025318.1|WP_000548347.1|611920_612910_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP025318.1|WP_000104211.1|610883_611822_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP025318.1|WP_000145820.1|610351_610696_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNIKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP025318.1|WP_001295544.1|622825_622990_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP025318.1|WP_024215656.1|623012_623714_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHAFTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>NZ_CP025318.1|WP_104951011.1|623818_624715_+|LysR-family-transcriptional-regulator
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLRKIPKLFSGK
>NZ_CP025318.1|WP_001198780.1|624765_625122_-|DUF805-domain-containing-protein
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>NZ_CP025318.1|WP_000384145.1|625363_625729_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP025318.1|WP_000531201.1|626021_627008_-|glutathione-S-transferase-family-protein
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP025318.1|WP_000603618.1|627077_627560_-|DoxX-family-protein
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP025318.1|WP_000096086.1|627655_627955_-|hypothetical-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP025318.1|WP_000785722.1|627944_628349_-|hypothetical-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP025318.1|WP_000031415.1|628351_628657_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: NZ_CP025318_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025318_2

1093481-1094363

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACC	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

14 spacers

cas3,cas8e,cse2gr11,cas5

The CRISPR arrays of NZ_CP025318_2

>merge|NZ_CP025318|2|1093481-1094363|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGTGATTCTCGCGACAAATTGCGTAACCGGGTAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGGCTTGTTTAATTGCGTGGAACGTCTCAATTGTGTTCCCCGCGCCAGCGGGGATAAACCTAGATCGCGCCACGAGGAAACGAATATGAACGGGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCCGCCAGGCCAGCGACACATCAGACAACTGGTGTTCCCCGCGCCAGCGGGGATAAACCGGTCTGTGATGGCCTGCTCGTGAGTCCGCGGCGGTGTTCCCCGCGCCAGCGGGGATAAACCGAATTTTTTATCCTCATAAACAGCCTCAGAAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGAGTTACGTCGCCATCGATATTAACGGAACACCGTGTTCCCCGCGCCAGCGGGGATAAACCGCCGCCGATTTCCCTGGCGTCAAAAGCGGTGAGGTGTTCCCCGCGCCAGCGGGGATAAACCGCTCTTTCTCAGTCATCTGGCGCTCAACGCCGGGTGTTCCCCGCGCCAGCGGGGATAAACCGGCAGCAATTGCCGGAGTTTTACTAATTGCCTCGTGTTCCCCGCGCCAGCGGGGATAAACCGTTTTGATTTCATTAACGGCGCTCCCCATATTTGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCGCCGTAGCGTGTCCACCTATTGTAGTAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGCTCCCTGTCAGTTGTAATCGATAACGTTGATGTGTTCCCCGCGCCAGCGGGGATAAACCGTATTACGCGCCAGCAATGCTGACAGCGGCAAAGTGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP025318|2|1|1093481-1094362|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGTGATTCTCGCGACAAATTGCGTAACCGGGTA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCGGCTTGTTTAATTGCGTGGAACGTCTCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACC	TAGATCGCGCCACGAGGAAACGAATATGAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GTGCCGCCAGGCCAGCGACACATCAGACAACTG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGTCTGTGATGGCCTGCTCGTGAGTCCGCGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATTTTTTATCCTCATAAACAGCCTCAGAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAGTTACGTCGCCATCGATATTAACGGAACACC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCCGCCGATTTCCCTGGCGTCAAAAGCGGTGAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCTCTTTCTCAGTCATCTGGCGCTCAACGCCGG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGCAGCAATTGCCGGAGTTTTACTAATTGCCTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GTTTTGATTTCATTAACGGCGCTCCCCATATTT
GTGTTCCCCGCGCCAGCGGGGATAAACC	GTGCGCCGTAGCGTGTCCACCTATTGTAGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACC	GTATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACC

>NZ_CP025318|2|2|1093481-1094363|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGATTCTCGCGACAAATTGCGTAACCGGGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTTGTTTAATTGCGTGGAACGTCTCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCT	AGATCGCGCCACGAGGAAACGAATATGAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCCGCCAGGCCAGCGACACATCAGACAACTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTGTGATGGCCTGCTCGTGAGTCCGCGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTTTTATCCTCATAAACAGCCTCAGAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTACGTCGCCATCGATATTAACGGAACACC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGCCGATTTCCCTGGCGTCAAAAGCGGTGAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCTTTCTCAGTCATCTGGCGCTCAACGCCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAGCAATTGCCGGAGTTTTACTAATTGCCTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGATTTCATTAACGGCGCTCCCCATATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCGTAGCGTGTCCACCTATTGTAGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP025318|2|1|1093481-1094363|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTGATTCTCGCGACAAATTGCGTAACCGGGTA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTTGTTTAATTGCGTGGAACGTCTCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCT	AGATCGCGCCACGAGGAAACGAATATGAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCCGCCAGGCCAGCGACACATCAGACAACTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTGTGATGGCCTGCTCGTGAGTCCGCGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AATTTTTTATCCTCATAAACAGCCTCAGAAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGTTACGTCGCCATCGATATTAACGGAACACC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGCCGATTTCCCTGGCGTCAAAAGCGGTGAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTCTTTCTCAGTCATCTGGCGCTCAACGCCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCAGCAATTGCCGGAGTTTTACTAATTGCCTC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGATTTCATTAACGGCGCTCCCCATATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCGTAGCGTGTCCACCTATTGTAGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025318.1\|WP_000581937.1\|1084839_1085088_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP025318.1\|WP_158672580.1\|1089989_1090916_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP025318.1\|WP_000034929.1\|1089591_1089954_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025318.1\|WP_000226815.1\|1082527_1084762_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP025318.1\|WP_001084104.1\|1104002_1105565_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP025318.1\|WP_104951054.1\|1092469_1093141_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP025318.1\|WP_000254745.1\|1085087_1085423_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP025318.1\|WP_000956458.1\|1100860_1101013_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP025318.1\|WP_000039843.1\|1099861_1100596_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP025318.1\|WP_001379137.1\|1091694_1092297_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP025318.1\|WP_000085068.1\|1106837_1107584_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP025318.1\|WP_000036723.1\|1088237_1089536_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP025318.1\|WP_001341832.1\|1103278_1103905_+\|hypothetical-protein	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP025318.1\|WP_077631692.1\|1101206_1103285_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP025318.1\|WP_001290706.1\|1098075_1099788_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP025318.1\|WP_000987944.1\|1095595_1095961_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP025318.1\|WP_001071648.1\|1085493_1086285_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP025318.1\|WP_000211936.1\|1096276_1098076_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP025318.1\|WP_104951055.1\|1105561_1106101_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP025318.1\|WP_000210878.1\|1086512_1088150_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437

Protein	Function_ID	Function_description	E-value
NZ_CP025318.1\|WP_000581937.1\|1084839_1085088_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP025318.1\|WP_158672580.1\|1089989_1090916_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	6.15097e-80
NZ_CP025318.1\|WP_000085068.1\|1106837_1107584_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.95914e-49
NZ_CP025318.1\|WP_000226815.1\|1082527_1084762_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP025318.1\|WP_001084104.1\|1104002_1105565_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP025318.1\|WP_104951054.1\|1092469_1093141_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.16196e-154
NZ_CP025318.1\|WP_000254745.1\|1085087_1085423_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NZ_CP025318.1\|WP_000956458.1\|1100860_1101013_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP025318.1\|WP_000039843.1\|1099861_1100596_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP025318.1\|WP_001379137.1\|1091694_1092297_-\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	1.00218e-77
NZ_CP025318.1\|WP_000036723.1\|1088237_1089536_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP025318.1\|WP_001341832.1\|1103278_1103905_+\|hypothetical-protein	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.00971e-26
NZ_CP025318.1\|WP_077631692.1\|1101206_1103285_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	4.26465e-143
NZ_CP025318.1\|WP_001290706.1\|1098075_1099788_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP025318.1\|WP_000987944.1\|1095595_1095961_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60
NZ_CP025318.1\|WP_001071648.1\|1085493_1086285_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP025318.1\|WP_000211936.1\|1096276_1098076_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP025318.1\|WP_104951055.1\|1105561_1106101_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	6.34316e-25
NZ_CP025318.1\|WP_000210878.1\|1086512_1088150_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0

>NZ_CP025318.1|WP_104951054.1|1092469_1093141_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGSASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIEASGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP025318.1|WP_001379137.1|1091694_1092297_-|LemA-family-protein
MLRTFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSNHEKDVLEAVTLARSQANRASSDLQQTPGNEQKLQAWQQAQAQVTRTLGQLTIISERYPELKAQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNASAH
>NZ_CP025318.1|WP_158672580.1|1089989_1090916_-|YgcG-family-protein
MESLPKNLILLLVLICSSAFAVQVPVPEFAKYINDLTGTLTREEVSTLTSQIKTLTQKSHAQLIVLVVETTGDETIEQYATRVFERWQPGHKNLDDGILLVVAWQDHTVHIEIGYGLEGILTDAQSGQIIRNSIIPAFKKGDLAVGLQQGIGDIETRLSENDLVNNTSPDHPLPFSGWWALLVWAIVLTFISARGYVKTLGVICFAAIILAFVLPIAGYSGSWGVLATLLCFATPFLVVAIAFTPFGRKVRDSMRSANRPSRYERSNSASRHSSSSSSSSSSSSSSFNNDNFSGGGGSSGGGGASGRW
>NZ_CP025318.1|WP_000034929.1|1089591_1089954_-|hypothetical-protein
MSKILANHPRLSKFVFGLFGAAGMIWLNKAFQGDELFQLITSLLALDTFVYFCIYSLINPIPEANDFLWDYKVHQRKYSSNISHNDFVSNVRNSRKIVRILILVGITFINVIALLTKLKM
>NZ_CP025318.1|WP_000036723.1|1088237_1089536_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP025318.1|WP_000210878.1|1086512_1088150_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP025318.1|WP_001071648.1|1085493_1086285_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP025318.1|WP_000254745.1|1085087_1085423_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP025318.1|WP_000581937.1|1084839_1085088_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP025318.1|WP_000226815.1|1082527_1084762_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP025318.1|WP_000987944.1|1095595_1095961_-|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>NZ_CP025318.1|WP_000211936.1|1096276_1098076_+|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLTGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGELRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>NZ_CP025318.1|WP_001290706.1|1098075_1099788_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>NZ_CP025318.1|WP_000039843.1|1099861_1100596_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP025318.1|WP_000956458.1|1100860_1101013_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP025318.1|WP_077631692.1|1101206_1103285_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPLNC
>NZ_CP025318.1|WP_001341832.1|1103278_1103905_+|hypothetical-protein
MLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>NZ_CP025318.1|WP_001084104.1|1104002_1105565_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPDSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP025318.1|WP_104951055.1|1105561_1106101_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDYLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP025318.1|WP_000085068.1|1106837_1107584_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE

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Crispr_ID: NZ_CP025318_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025318_3

1109523-1109735

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

3 spacers

cas2,cas1,cas6e,cas5,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP025318_3

>merge|NZ_CP025318|3|1109523-1109735|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGTTCTGCTGCTGGTTTGAAGAGGCGCTGGCACGCGTGTTCCCCGCGCCAGCGGGGATAAACCGCAAAAAAATAGATTGGAAAACATTTAGATTCAGTGTTCCCCGCGCCAGCGGGGATAAACCGTGACTGCGGTTCAAAATCTCCGGCACACGTCCGTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP025318|3|2|1109523-1109735|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTCTGCTGCTGGTTTGAAGAGGCGCTGGCACGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAAAAAATAGATTGGAAAACATTTAGATTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGACTGCGGTTCAAAATCTCCGGCACACGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP025318|3|3|1109523-1109735|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTCTGCTGCTGGTTTGAAGAGGCGCTGGCACGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAAAAAATAGATTGGAAAACATTTAGATTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGACTGCGGTTCAAAATCTCCGGCACACGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP025318|3|2|1109523-1109735|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTCTGCTGCTGGTTTGAAGAGGCGCTGGCACGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAAAAAATAGATTGGAAAACATTTAGATTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGACTGCGGTTCAAAATCTCCGGCACACGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025318.1\|WP_000039843.1\|1099861_1100596_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP025318.1\|WP_000085068.1\|1106837_1107584_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP025318.1\|WP_000517476.1\|1114614_1114926_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP025318.1\|WP_001246104.1\|1114097_1114421_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP025318.1\|WP_000372108.1\|1111105_1112014_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP025318.1\|WP_104951055.1\|1105561_1106101_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP025318.1\|WP_001295182.1\|1117160_1117922_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP025318.1\|WP_000956458.1\|1100860_1101013_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP025318.1\|WP_001090345.1\|1112015_1113443_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP025318.1\|WP_000490403.1\|1109816_1110854_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP025318.1\|WP_001341832.1\|1103278_1103905_+\|hypothetical-protein	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP025318.1\|WP_001173673.1\|1113442_1114048_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP025318.1\|WP_077631692.1\|1101206_1103285_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP025318.1\|WP_001084104.1\|1104002_1105565_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP025318.1\|WP_000246138.1\|1114944_1115655_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP025318.1\|WP_000568943.1\|1116130_1117180_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP025318.1\|WP_001219242.1\|1115654_1116134_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP025318.1\|WP_000144875.1\|1108212_1109133_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP025318.1\|WP_000063176.1\|1109132_1109426_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP025318.1\|WP_000281434.1\|1107565_1108216_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869

Protein	Function_ID	Function_description	E-value
NZ_CP025318.1\|WP_000039843.1\|1099861_1100596_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP025318.1\|WP_000085068.1\|1106837_1107584_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.95914e-49
NZ_CP025318.1\|WP_000517476.1\|1114614_1114926_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP025318.1\|WP_001246104.1\|1114097_1114421_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP025318.1\|WP_000372108.1\|1111105_1112014_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP025318.1\|WP_104951055.1\|1105561_1106101_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	6.34316e-25
NZ_CP025318.1\|WP_001295182.1\|1117160_1117922_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP025318.1\|WP_000956458.1\|1100860_1101013_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP025318.1\|WP_001090345.1\|1112015_1113443_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP025318.1\|WP_000490403.1\|1109816_1110854_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP025318.1\|WP_001341832.1\|1103278_1103905_+\|hypothetical-protein	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.00971e-26
NZ_CP025318.1\|WP_001173673.1\|1113442_1114048_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP025318.1\|WP_077631692.1\|1101206_1103285_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	4.26465e-143
NZ_CP025318.1\|WP_001084104.1\|1104002_1105565_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP025318.1\|WP_000246138.1\|1114944_1115655_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP025318.1\|WP_000568943.1\|1116130_1117180_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP025318.1\|WP_001219242.1\|1115654_1116134_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP025318.1\|WP_000144875.1\|1108212_1109133_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.70125e-157
NZ_CP025318.1\|WP_000063176.1\|1109132_1109426_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP025318.1\|WP_000281434.1\|1107565_1108216_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.16907e-91

>NZ_CP025318.1|WP_000063176.1|1109132_1109426_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP025318.1|WP_000144875.1|1108212_1109133_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLINKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRG
>NZ_CP025318.1|WP_000281434.1|1107565_1108216_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQARPAESETFTIECRPFVSELRTGQSLCFNLRANPTICKAGKRHDLLMEAKRQVKGQAEGRDIWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENTRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP025318.1|WP_000085068.1|1106837_1107584_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP025318.1|WP_104951055.1|1105561_1106101_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDYLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP025318.1|WP_001084104.1|1104002_1105565_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPDSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP025318.1|WP_001341832.1|1103278_1103905_+|hypothetical-protein
MLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>NZ_CP025318.1|WP_077631692.1|1101206_1103285_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPLNC
>NZ_CP025318.1|WP_000956458.1|1100860_1101013_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP025318.1|WP_000039843.1|1099861_1100596_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP025318.1|WP_000490403.1|1109816_1110854_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP025318.1|WP_000372108.1|1111105_1112014_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP025318.1|WP_001090345.1|1112015_1113443_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARIDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPKNEAAVASSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP025318.1|WP_001173673.1|1113442_1114048_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP025318.1|WP_001246104.1|1114097_1114421_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP025318.1|WP_000517476.1|1114614_1114926_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP025318.1|WP_000246138.1|1114944_1115655_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP025318.1|WP_001219242.1|1115654_1116134_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP025318.1|WP_000568943.1|1116130_1117180_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP025318.1|WP_001295182.1|1117160_1117922_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP025318_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025318_4

2265805-2265928

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025318_4

>merge|NZ_CP025318|4|2265805-2265928|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP025318|4|4|2265805-2265928|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025318.1\|WP_000102278.1\|2274824_2274914_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP025318.1\|WP_000269501.1\|2272571_2273504_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP025318.1\|WP_000716922.1\|2263634_2265239_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP025318.1\|WP_001295403.1\|2255258_2256671_-\|pyruvate-kinase-PykF	unknown	unknown	gnl\|CDD\|181699
NZ_CP025318.1\|WP_000493947.1\|2269127_2269769_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP025318.1\|WP_001174946.1\|2267539_2268913_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP025318.1\|WP_001349911.1\|2261356_2262025_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP025318.1\|WP_001070230.1\|2257892_2258519_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP025318.1\|WP_001182362.1\|2271247_2272459_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP025318.1\|WP_000528342.1\|2257227_2257437_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP025318.1\|WP_000504358.1\|2260645_2261293_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP025318.1\|WP_000007283.1\|2276394_2276976_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP025318.1\|WP_104951140.1\|2266242_2267499_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP025318.1\|WP_000587560.1\|2262810_2263623_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP025318.1\|WP_000098911.1\|2269808_2270957_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP025318.1\|WP_001273518.1\|2258539_2260642_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP025318.1\|WP_000212657.1\|2265364_2265670_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP025318.1\|WP_001069997.1\|2262021_2262807_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP025318.1\|WP_000190982.1\|2273500_2274526_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP025318.1\|WP_000701040.1\|2275079_2276249_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371

Protein	Function_ID	Function_description	E-value
NZ_CP025318.1\|WP_000269501.1\|2272571_2273504_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP025318.1\|WP_000716922.1\|2263634_2265239_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP025318.1\|WP_001295403.1\|2255258_2256671_-\|pyruvate-kinase-PykF	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP025318.1\|WP_000493947.1\|2269127_2269769_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP025318.1\|WP_001174946.1\|2267539_2268913_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP025318.1\|WP_001349911.1\|2261356_2262025_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	7.32003e-76
NZ_CP025318.1\|WP_001070230.1\|2257892_2258519_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP025318.1\|WP_001182362.1\|2271247_2272459_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP025318.1\|WP_000528342.1\|2257227_2257437_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP025318.1\|WP_000504358.1\|2260645_2261293_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	2.09841e-122
NZ_CP025318.1\|WP_000007283.1\|2276394_2276976_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP025318.1\|WP_104951140.1\|2266242_2267499_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP025318.1\|WP_000587560.1\|2262810_2263623_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.20825e-175
NZ_CP025318.1\|WP_000098911.1\|2269808_2270957_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP025318.1\|WP_001273518.1\|2258539_2260642_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP025318.1\|WP_000212657.1\|2265364_2265670_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
NZ_CP025318.1\|WP_001069997.1\|2262021_2262807_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.33298e-163
NZ_CP025318.1\|WP_000190982.1\|2273500_2274526_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP025318.1\|WP_000701040.1\|2275079_2276249_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98

>NZ_CP025318.1|WP_000212657.1|2265364_2265670_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP025318.1|WP_000716922.1|2263634_2265239_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP025318.1|WP_000587560.1|2262810_2263623_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC
>NZ_CP025318.1|WP_001069997.1|2262021_2262807_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP025318.1|WP_001349911.1|2261356_2262025_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP025318.1|WP_000504358.1|2260645_2261293_+|YdhW-family-putative-oxidoreductase-system-protein
MGEMNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSVAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP025318.1|WP_001273518.1|2258539_2260642_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIHWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>NZ_CP025318.1|WP_001070230.1|2257892_2258519_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP025318.1|WP_000528342.1|2257227_2257437_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP025318.1|WP_001295403.1|2255258_2256671_-|pyruvate-kinase-PykF
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP025318.1|WP_104951140.1|2266242_2267499_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILGGSTVKGDSVTFSVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP025318.1|WP_001174946.1|2267539_2268913_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVKPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
>NZ_CP025318.1|WP_000493947.1|2269127_2269769_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP025318.1|WP_000098911.1|2269808_2270957_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP025318.1|WP_001182362.1|2271247_2272459_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVDCQNHGNAEVAHSESH
>NZ_CP025318.1|WP_000269501.1|2272571_2273504_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP025318.1|WP_000190982.1|2273500_2274526_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP025318.1|WP_000102278.1|2274824_2274914_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP025318.1|WP_000701040.1|2275079_2276249_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP025318.1|WP_000007283.1|2276394_2276976_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Crispr_ID: NZ_CP025318_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025318_5

3057152-3057243

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025318_5

>merge|NZ_CP025318|5|3057152-3057243|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP025318|5|5|3057152-3057243|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025318.1\|WP_000979516.1\|3046402_3046612_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025318.1\|WP_000097604.1\|3060078_3061338_-\|YccE-family-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP025318.1\|WP_001345413.1\|3053783_3054584_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP025318.1\|WP_000420629.1\|3061597_3062518_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP025318.1\|WP_158672594.1\|3051594_3052686_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP025318.1\|WP_000024561.1\|3062517_3062823_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP025318.1\|WP_001044263.1\|3058548_3059790_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP025318.1\|WP_001143120.1\|3058283_3058511_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP025318.1\|WP_001120112.1\|3067359_3068052_+\|two-component-system-response-regulator-TorR	unknown	unknown	gnl\|CDD\|182711
NZ_CP025318.1\|WP_104951221.1\|3046666_3050629_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP025318.1\|WP_001307708.1\|3052685_3053378_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP025318.1\|WP_104951224.1\|3057666_3058263_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP025318.1\|WP_001230242.1\|3066057_3067230_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992
NZ_CP025318.1\|WP_001126777.1\|3053389_3053776_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP025318.1\|WP_001331086.1\|3050668_3051307_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP025318.1\|WP_104951225.1\|3062915_3063515_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP025318.1\|WP_104951223.1\|3054593_3055184_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP025318.1\|WP_001240628.1\|3055709_3057038_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP025318.1\|WP_001062102.1\|3063511_3066058_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP025318.1\|WP_001028095.1\|3055194_3055689_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654

Protein	Function_ID	Function_description	E-value
NZ_CP025318.1\|WP_000097604.1\|3060078_3061338_-\|YccE-family-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP025318.1\|WP_001345413.1\|3053783_3054584_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	1.24393e-141
NZ_CP025318.1\|WP_000420629.1\|3061597_3062518_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP025318.1\|WP_158672594.1\|3051594_3052686_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP025318.1\|WP_000024561.1\|3062517_3062823_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	2.74017e-64
NZ_CP025318.1\|WP_001044263.1\|3058548_3059790_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP025318.1\|WP_001143120.1\|3058283_3058511_+\|hypothetical-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP025318.1\|WP_001120112.1\|3067359_3068052_+\|two-component-system-response-regulator-TorR	gnl\|CDD\|182711	PRK10766, PRK10766, two-component system response regulator TorR.	5.89892e-138
NZ_CP025318.1\|WP_104951221.1\|3046666_3050629_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP025318.1\|WP_001307708.1\|3052685_3053378_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	5.84226e-169
NZ_CP025318.1\|WP_104951224.1\|3057666_3058263_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	6.82669e-132
NZ_CP025318.1\|WP_001230242.1\|3066057_3067230_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0
NZ_CP025318.1\|WP_001126777.1\|3053389_3053776_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	6.69692e-84
NZ_CP025318.1\|WP_001331086.1\|3050668_3051307_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	8.77004e-153
NZ_CP025318.1\|WP_104951225.1\|3062915_3063515_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	7.06372e-84
NZ_CP025318.1\|WP_104951223.1\|3054593_3055184_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	2.71003e-129
NZ_CP025318.1\|WP_001240628.1\|3055709_3057038_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP025318.1\|WP_001062102.1\|3063511_3066058_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP025318.1\|WP_001028095.1\|3055194_3055689_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	3.76111e-106

>NZ_CP025318.1|WP_001240628.1|3055709_3057038_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPYERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNLLGLGKAVDFTLVSHAAWFGLPHFSTPAFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>NZ_CP025318.1|WP_001028095.1|3055194_3055689_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
>NZ_CP025318.1|WP_104951223.1|3054593_3055184_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKLGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
>NZ_CP025318.1|WP_001345413.1|3053783_3054584_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP025318.1|WP_001126777.1|3053389_3053776_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLEIIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP025318.1|WP_001307708.1|3052685_3053378_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>NZ_CP025318.1|WP_158672594.1|3051594_3052686_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDELANVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP025318.1|WP_001331086.1|3050668_3051307_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTKGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
>NZ_CP025318.1|WP_104951221.1|3046666_3050629_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEAILSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIAPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP025318.1|WP_000979516.1|3046402_3046612_-|hypothetical-protein
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NZ_CP025318.1|WP_104951224.1|3057666_3058263_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGTTTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP025318.1|WP_001143120.1|3058283_3058511_+|hypothetical-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP025318.1|WP_001044263.1|3058548_3059790_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAAAVAGIVLIASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECPPPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDANGFCPMDKFDSVLNEAVK
>NZ_CP025318.1|WP_000097604.1|3060078_3061338_-|YccE-family-protein
MSSNIHGISCTANNYLKQAWNNIKNEHEKNQKYSITLFENTLVCFMRLYKEIRRQKAEDYIPCLECDSLEKEFEEMQNDNDLSLFLRTLRTNDTETYSGVSEGITYTIQYVRDIDIVRVSLPGRGSESITDFKGYYWYGFMEYIENINACDDVFSEYCLDDENMSIQPEWINTPGISDLDTGIDLSGISFIQSEINKTYGLKYAPVDGDGYCLLRAILVLKEHEYSWALGSHKTQKQVYEEFIKIVDKQTIEALVDTAFNDLREDVKTLFGVNLQSDNKIQGQGGFLSWSFLSFKKEFIDSCLNDKKCILHLPEFIFNDNKVRLVLDTDPEQRVNEVKNFLTALSDSICSLFIVNSNMASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKLNNKEMNAQLDYLNRYAIY
>NZ_CP025318.1|WP_000420629.1|3061597_3062518_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHSDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGHDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP025318.1|WP_000024561.1|3062517_3062823_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVTHP
>NZ_CP025318.1|WP_104951225.1|3062915_3063515_-|molecular-chaperone-TorD
MTTLTAQQIACIYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNTLENRIAALTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPTDHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVARCHQHDSFGFYAALSQLLLVLVECDHQNR
>NZ_CP025318.1|WP_001062102.1|3063511_3066058_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS
>NZ_CP025318.1|WP_001230242.1|3066057_3067230_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>NZ_CP025318.1|WP_001120112.1|3067359_3068052_+|two-component-system-response-regulator-TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC

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Crispr_ID: NZ_CP025318_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025318_6

3472302-3472446

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025318_6

>merge|NZ_CP025318|6|3472302-3472446|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>NZ_CP025318|6|6|3472302-3472446|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025318.1\|WP_000593936.1\|3472469_3474731_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NZ_CP025318.1\|WP_001356069.1\|3477658_3478612_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP025318.1\|WP_000748282.1\|3467557_3468172_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025318.1\|WP_000545741.1\|3469344_3469512_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025318.1\|WP_000213425.1\|3479802_3480621_+\|pyridoxal-phosphatase	unknown	unknown	gnl\|CDD\|182523
NZ_CP025318.1\|WP_001303849.1\|3469551_3469770_+\|excisionase	unknown	unknown	gnl\|CDD\|116439
NZ_CP025318.1\|WP_001395510.1\|3466409_3466691_+\|cell-division-protein-ZapA	unknown	unknown	unknown
NZ_CP025318.1\|WP_000815441.1\|3478652_3479648_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NZ_CP025318.1\|WP_000763369.1\|3466789_3467011_+\|TraR/DksA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|222775
NZ_CP025318.1\|WP_000891683.1\|3480621_3481680_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP025318.1\|WP_000723652.1\|3476422_3477475_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
NZ_CP025318.1\|WP_001091569.1\|3470952_3472236_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP025318.1\|WP_000891515.1\|3483311_3483461_-\|multidrug-efflux-pump-accessory-protein-AcrZ	unknown	unknown	gnl\|CDD\|371231
NZ_CP025318.1\|WP_000533646.1\|3469747_3470818_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271181
NZ_CP025318.1\|WP_001036486.1\|3474913_3476347_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP025318.1\|WP_000111054.1\|3467007_3467259_+\|ead/Ea22-like-family-protein	unknown	unknown	gnl\|CDD\|379401
NZ_CP025318.1\|WP_000762731.1\|3468832_3469261_+\|DUF2513-domain-containing-protein	unknown	unknown	gnl\|CDD\|378481
NZ_CP025318.1\|WP_000604032.1\|3481682_3482372_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_CP025318.1\|WP_000113005.1\|3482371_3483145_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NZ_CP025318.1\|WP_104951258.1\|3468465_3468804_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025318.1\|WP_000593936.1\|3472469_3474731_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NZ_CP025318.1\|WP_001356069.1\|3477658_3478612_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.3313e-82
NZ_CP025318.1\|WP_000213425.1\|3479802_3480621_+\|pyridoxal-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
NZ_CP025318.1\|WP_001303849.1\|3469551_3469770_+\|excisionase	gnl\|CDD\|116439	pfam07825, Exc, Excisionase-like protein. The phage-encoded excisionase protein (Xis) is involved in excisive recombination by regulating the assembly of the excisive intasome and by inhibiting viral integration. It adopts an unusual 'winged'-helix structure in which two alpha helices are packed against two extended strands. Also present in the structure is a two-stranded anti-parallel beta-sheet, whose strands are connected by a four-residue 'wing'. During interaction with DNA, helix alpha2 is thought to insert into the major groove, while the wing contacts the adjacent minor groove or phosphodiester backbone. The C-terminal region of Xis is involved in interaction with phage-encoded integrase (Int), and a putative C-terminal alpha helix may fold upon interaction with Int and/or DNA.	8.49552e-35
NZ_CP025318.1\|WP_000113005.1\|3482371_3483145_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
NZ_CP025318.1\|WP_000815441.1\|3478652_3479648_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NZ_CP025318.1\|WP_000763369.1\|3466789_3467011_+\|TraR/DksA-family-transcriptional-regulator	gnl\|CDD\|222775	PHA00080, PHA00080, DksA-like zinc finger domain containing protein.	3.3323e-27
NZ_CP025318.1\|WP_000891683.1\|3480621_3481680_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP025318.1\|WP_000723652.1\|3476422_3477475_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NZ_CP025318.1\|WP_001091569.1\|3470952_3472236_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP025318.1\|WP_000533646.1\|3469747_3470818_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	8.02573e-62
NZ_CP025318.1\|WP_000891515.1\|3483311_3483461_-\|multidrug-efflux-pump-accessory-protein-AcrZ	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
NZ_CP025318.1\|WP_001036486.1\|3474913_3476347_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NZ_CP025318.1\|WP_000762731.1\|3468832_3469261_+\|DUF2513-domain-containing-protein	gnl\|CDD\|378481	pfam10711, DUF2513, Hypothetical protein (DUF2513). This family is found in bacteria. The function is not known.	3.87415e-10
NZ_CP025318.1\|WP_000604032.1\|3481682_3482372_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	9.04539e-146
NZ_CP025318.1\|WP_000111054.1\|3467007_3467259_+\|ead/Ea22-like-family-protein	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	3.43098e-13

>NZ_CP025318.1|WP_001091569.1|3470952_3472236_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NZ_CP025318.1|WP_000533646.1|3469747_3470818_+|tyrosine-type-recombinase/integrase
MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFSGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNPVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTVLHVDALGISMKETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
>NZ_CP025318.1|WP_001303849.1|3469551_3469770_+|excisionase
MYLTLQEWNARQRRPRSLETVRRWVRECRIFPPPVKDGREYLFHESAVKVDLNRPVTGSLLKRIRNGKKAKS
>NZ_CP025318.1|WP_000545741.1|3469344_3469512_+|hypothetical-protein
MHFRVTGEWNGEPFNRVIEAENINDCYNHWMIWAQIAHADVTNIRIEELKEHQAA
>NZ_CP025318.1|WP_000762731.1|3468832_3469261_+|DUF2513-domain-containing-protein
MKLDQQYLKDLLIAFEKTRGPDTMLSELEDNGFNRYDQDFIFHMRLLCDYELIVRVDGKPGFGHILSKALGEGVGYSWIEVPLRLTARGHDFIADLRQKDVWQAIKTNFKDEGISTLMSVSKSLAKGFARKKIKDITGIDIE
>NZ_CP025318.1|WP_104951258.1|3468465_3468804_+|hypothetical-protein
MAKSATEHKADQRAKQASSGMRKLELVLDAQEIEMLERNCATRRFRRAPCEFGEYIALLSRQDDARVRWRIKSISRKRCGKCGERVPVNSCPFNGDSQCWVTKGWHETKLMI
>NZ_CP025318.1|WP_000748282.1|3467557_3468172_+|hypothetical-protein
MKKSILILGLTLIVSSQIPSAMAKNESKLWVVVDRTERHTCPSSKCGVAGKLFFREGVDFLEKKGEWVRITEPYSASCVGGESEYIKEGNKSCTRKNGIVNGKFSEWVKLSDLSSERPSDPAENASGDDTLIKGSDDYRIYKKEFSSAARKLINEGVCTESDFKEIGGWMASSNKGENIYFTYCGGMTLSNRIYLDVKSGKTFR
>NZ_CP025318.1|WP_000111054.1|3467007_3467259_+|ead/Ea22-like-family-protein
MSVIHSQALREAAEQAMPDNWGFDADLFHELVTPSIVLTLLDERERNQQYIKRRDQENEDIALTVGKLRVELETAKIKTQRAA
>NZ_CP025318.1|WP_000763369.1|3466789_3467011_+|TraR/DksA-family-transcriptional-regulator
MADIIDSASEIEELQRNTAIKMRRLNHQAVSATHCCECGDPIDELRRLAVQGCRTCASCQEDLELISKQRGSK
>NZ_CP025318.1|WP_001395510.1|3466409_3466691_+|cell-division-protein-ZapA
MHFSGSGLHILCAYACRHGACSMTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>NZ_CP025318.1|WP_000593936.1|3472469_3474731_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NZ_CP025318.1|WP_001036486.1|3474913_3476347_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGSTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NZ_CP025318.1|WP_000723652.1|3476422_3477475_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NZ_CP025318.1|WP_001356069.1|3477658_3478612_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRHKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>NZ_CP025318.1|WP_000815441.1|3478652_3479648_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQRQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NZ_CP025318.1|WP_000213425.1|3479802_3480621_+|pyridoxal-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NZ_CP025318.1|WP_000891683.1|3480621_3481680_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMAKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>NZ_CP025318.1|WP_000604032.1|3481682_3482372_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITIPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NZ_CP025318.1|WP_000113005.1|3482371_3483145_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNTLADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>NZ_CP025318.1|WP_000891515.1|3483311_3483461_-|multidrug-efflux-pump-accessory-protein-AcrZ
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: NZ_CP025318_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025318_7

3896612-3896756

Orphan

Consensus_repeat	Method
TAAACCGTAGGCCTGATAAGACGCGCAAAGCGTCGCATCAGGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025318_7

>merge|NZ_CP025318|7|3896612-3896756|CRISPRCasFinder
TAAACCGTAGGCCTGATAAGACGCGCAAAGCGTCGCATCAGGCATGGCGCACGACTGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACACTTCGCCCATAAACCGTAGGCCTGATAAGACGCGCATAGCGTCGCATCAGGCAT

>NZ_CP025318|7|7|3896612-3896756|CRISPRCasFinder
TAAACCGTAGGCCTGATAAGACGCGCAAAGCGTCGCATCAGGCAT	GGCGCACGACTGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACACTTCGCCCA
TAAACCGTAGGCCTGATAAGACGCGCATAGCGTCGCATCAGGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025318.1\|WP_001013499.1\|3898805_3899819_-\|4-hydroxy-2-oxovalerate-aldolase	unknown	unknown	gnl\|CDD\|181282
NZ_CP025318.1\|WP_000044314.1\|3899815_3900766_-\|acetaldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236227
NZ_CP025318.1\|WP_000107624.1\|3897418_3898630_-\|3-(3-hydroxy-phenyl)propionate-transporter-MhpT	unknown	unknown	gnl\|CDD\|236927
NZ_CP025318.1\|WP_001096705.1\|3896777_3897317_-\|DUF2058-domain-containing-protein	unknown	unknown	gnl\|CDD\|225664
NZ_CP025318.1\|WP_001018416.1\|3889232_3890195_-\|taurine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|183158
NZ_CP025318.1\|WP_001007449.1\|3903411_3905076_-\|bifunctional-3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic-acid-hydroxylase	unknown	unknown	gnl\|CDD\|235727
NZ_CP025318.1\|WP_072157913.1\|3892665_3893247_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100060
NZ_CP025318.1\|WP_000842102.1\|3894516_3895626_+\|S-(hydroxymethyl)glutathione-dehydrogenase	unknown	unknown	gnl\|CDD\|176260
NZ_CP025318.1\|WP_000805910.1\|3906176_3907259_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|181929
NZ_CP025318.1\|WP_089645602.1\|3891491_3892688_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|224136
NZ_CP025318.1\|WP_000543459.1\|3902465_3903410_-\|3-carboxyethylcatechol-2,3-dioxygenase	unknown	unknown	gnl\|CDD\|153377
NZ_CP025318.1\|WP_000596085.1\|3893248_3894022_+\|YaiO-family-outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|275183
NZ_CP025318.1\|WP_000121898.1\|3901581_3902448_-\|2-hydroxy-6-oxonona-2,4-dienedioate-hydrolase	unknown	unknown	gnl\|CDD\|132386
NZ_CP025318.1\|WP_104951281.1\|3895718_3896552_+\|S-formylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|131868
NZ_CP025318.1\|WP_000114595.1\|3887628_3888456_-\|taurine-ABC-transporter-permease-TauC	unknown	unknown	gnl\|CDD\|182276
NZ_CP025318.1\|WP_001316894.1\|3905152_3906100_+\|DNA-binding-transcriptional-activator-MhpR	unknown	unknown	gnl\|CDD\|182100
NZ_CP025318.1\|WP_104951280.1\|3888452_3889220_-\|taurine-ABC-transporter-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|183056
NZ_CP025318.1\|WP_089552453.1\|3894206_3894482_+\|formaldehyde-responsive-transcriptional-repressor-FrmR	unknown	unknown	gnl\|CDD\|183095
NZ_CP025318.1\|WP_024215455.1\|3890810_3891482_+\|PIG-L-family-deacetylase	unknown	unknown	gnl\|CDD\|225031
NZ_CP025318.1\|WP_000160734.1\|3900762_3901572_-\|2-keto-4-pentenoate-hydratase	unknown	unknown	gnl\|CDD\|183092

Protein	Function_ID	Function_description	E-value
NZ_CP025318.1\|WP_001013499.1\|3898805_3899819_-\|4-hydroxy-2-oxovalerate-aldolase	gnl\|CDD\|181282	PRK08195, PRK08195, 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated.	0
NZ_CP025318.1\|WP_000044314.1\|3899815_3900766_-\|acetaldehyde-dehydrogenase	gnl\|CDD\|236227	PRK08300, PRK08300, acetaldehyde dehydrogenase; Validated.	0
NZ_CP025318.1\|WP_000107624.1\|3897418_3898630_-\|3-(3-hydroxy-phenyl)propionate-transporter-MhpT	gnl\|CDD\|236927	PRK11551, PRK11551, putative 3-hydroxyphenylpropionic transporter MhpT; Provisional.	0
NZ_CP025318.1\|WP_001096705.1\|3896777_3897317_-\|DUF2058-domain-containing-protein	gnl\|CDD\|225664	COG3122, COG3122, Uncharacterized protein conserved in bacteria [Function unknown].	8.4008e-82
NZ_CP025318.1\|WP_001018416.1\|3889232_3890195_-\|taurine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|183158	PRK11480, tauA, taurine transporter substrate binding subunit; Provisional.	0
NZ_CP025318.1\|WP_001007449.1\|3903411_3905076_-\|bifunctional-3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic-acid-hydroxylase	gnl\|CDD\|235727	PRK06183, mhpA, bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase.	0
NZ_CP025318.1\|WP_072157913.1\|3892665_3893247_+\|acetyltransferase	gnl\|CDD\|100060	cd05636, LbH_G1P_TT_C_like, Putative glucose-1-phosphate thymidylyltransferase, C-terminal Left-handed parallel beta-Helix (LbH) domain: Proteins in this family show simlarity to glucose-1-phosphate adenylyltransferases in that they contain N-terminal catalytic domains that resemble a dinucleotide-binding Rossmann fold and C-terminal LbH fold domains. Members in this family are predicted to be glucose-1-phosphate thymidylyltransferases, which are involved in the dTDP-L-rhamnose biosynthetic pathway. Glucose-1-phosphate thymidylyltransferase catalyzes the synthesis of deoxy-thymidine di-phosphate (dTDP)-L-rhamnose, an important component of the cell wall of many microorganisms. The C-terminal LbH domain contains multiple turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes showing acyltransferase activity.	2.71856e-40
NZ_CP025318.1\|WP_000842102.1\|3894516_3895626_+\|S-(hydroxymethyl)glutathione-dehydrogenase	gnl\|CDD\|176260	cd08300, alcohol_DH_class_III, class III alcohol dehydrogenases. Members identified as glutathione-dependent formaldehyde dehydrogenase(FDH), a member of the zinc dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. MDH family uses NAD(H) as a cofactor in the interconversion of alcohols and aldehydes or ketones. Like many zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), these FDHs form dimers, with 4 zinc ions per dimer. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	0
NZ_CP025318.1\|WP_000805910.1\|3906176_3907259_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|181929	PRK09526, lacI, lac repressor; Reviewed.	0
NZ_CP025318.1\|WP_089645602.1\|3891491_3892688_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|224136	COG1215, COG1215, Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane].	8.87399e-52
NZ_CP025318.1\|WP_000543459.1\|3902465_3903410_-\|3-carboxyethylcatechol-2,3-dioxygenase	gnl\|CDD\|153377	cd07365, MhpB_like, Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate. 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB) catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate, yielding the product 2-hydroxy-6-oxo-nona-2,4-diene 1,9-dicarboxylate. It is an essential enzyme in the beta-phenylpropionic degradation pathway, in which beta-phenylpropionic is first hydrolyzed to produce 2,3-dihydroxyphenylpropionate. The enzyme is a member of the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon. LigAB-like class III enzymes are usually composed of two subunits, designated A and B, which form a tetramer composed of two copies of each subunit. This model represents the catalytic subunit, B. MhpB is likely to be a tetramer.	0
NZ_CP025318.1\|WP_000596085.1\|3893248_3894022_+\|YaiO-family-outer-membrane-beta-barrel-protein	gnl\|CDD\|275183	TIGR04390, hypothetical_protein, outer membrane protein, YaiO family. Members of this family share a domain of bacterial outer membrane beta barrel, up to the protein C-terminal residue (usually Phe or Trp). The member YaiO was shown experimentally to be localized to the outer membrane. [Unknown function, General].	5.60946e-48
NZ_CP025318.1\|WP_000121898.1\|3901581_3902448_-\|2-hydroxy-6-oxonona-2,4-dienedioate-hydrolase	gnl\|CDD\|132386	TIGR03343, 2-hydroxy-6-oxo-6-phenylhexa-24-dienoate_hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase. Members of this family are 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, or HOPD hydrolase, the BphD protein of biphenyl degradation. BphD acts on the product of ring meta-cleavage by BphC. Many species carrying bphC and bphD are capable of degrading polychlorinated biphenyls as well as biphenyl itself.	1.18395e-119
NZ_CP025318.1\|WP_104951281.1\|3895718_3896552_+\|S-formylglutathione-hydrolase	gnl\|CDD\|131868	TIGR02821, S-formylglutathione_hydrolase, S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well. [Cellular processes, Detoxification].	4.30081e-133
NZ_CP025318.1\|WP_000114595.1\|3887628_3888456_-\|taurine-ABC-transporter-permease-TauC	gnl\|CDD\|182276	PRK10160, PRK10160, taurine ABC transporter permease TauC.	7.56521e-168
NZ_CP025318.1\|WP_001316894.1\|3905152_3906100_+\|DNA-binding-transcriptional-activator-MhpR	gnl\|CDD\|182100	PRK09834, PRK09834, DNA-binding transcriptional regulator.	1.03142e-150
NZ_CP025318.1\|WP_104951280.1\|3888452_3889220_-\|taurine-ABC-transporter-ATP-binding-subunit	gnl\|CDD\|183056	PRK11248, tauB, taurine ABC transporter ATP-binding subunit.	0
NZ_CP025318.1\|WP_089552453.1\|3894206_3894482_+\|formaldehyde-responsive-transcriptional-repressor-FrmR	gnl\|CDD\|183095	PRK11352, PRK11352, formaldehyde-responsive transcriptional repressor FrmR.	9.24551e-50
NZ_CP025318.1\|WP_024215455.1\|3890810_3891482_+\|PIG-L-family-deacetylase	gnl\|CDD\|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	1.81632e-43
NZ_CP025318.1\|WP_000160734.1\|3900762_3901572_-\|2-keto-4-pentenoate-hydratase	gnl\|CDD\|183092	PRK11342, mhpD, 2-keto-4-pentenoate hydratase; Provisional.	0

>NZ_CP025318.1|WP_104951281.1|3895718_3896552_+|S-formylglutathione-hydrolase
MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLPVLYWLSGLTCNEQNFITKSGVQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIRNELPDLVMQHFPATTRKSISGHSMGGLGALVLALRNPDEYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNMR
>NZ_CP025318.1|WP_000842102.1|3894516_3895626_+|S-(hydroxymethyl)glutathione-dehydrogenase
MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY
>NZ_CP025318.1|WP_089552453.1|3894206_3894482_+|formaldehyde-responsive-transcriptional-repressor-FrmR
MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAEYRAILQQIAAVRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK
>NZ_CP025318.1|WP_000596085.1|3893248_3894022_+|YaiO-family-outer-membrane-beta-barrel-protein
MIKRTLLAAAIFSALPAYAGLTSITAGYDFTDYSGDHGNRNLAYAELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTPVFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVITSYRYTHYDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQRIQPLTEQLNLGLTAGKVWYDTPTDDYNGLQLAAHLTWKF
>NZ_CP025318.1|WP_072157913.1|3892665_3893247_+|acetyltransferase
MKNYLKLNVKEKNIQIADQVIIDETAGEVVIGANTRICHGAVIQGPVVIGANCLIGNYAFIRPGTIISNGVKIGFATEIKNAVIESEATIGPQCFIADSVVANQAYLGAQVRTSNHRLDEQPVSVRTPEGIIATGCDKLGCYIGQRSRLGVQVIILPGRIISPNTQLGPRVIVERNLPAGTYSLRQELIRTGD
>NZ_CP025318.1|WP_089645602.1|3891491_3892688_+|glycosyltransferase-family-2-protein
MKTWIFICMSIAMLLWFLSTLRRKPSQKKGCIDAIIPAYNEGPCLAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEIKRKWGDRFVAVTQKNTGKGGALMNGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHIRATVKLPMIVMKRTLQQLLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTLVANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIFPMLLVVIYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWIGVVCVIGAFSAWFHRCWLLVPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGTEKLSEA
>NZ_CP025318.1|WP_024215455.1|3890810_3891482_+|PIG-L-family-deacetylase
MDKVLDSALLSSANKRKGILAIGAHPDDIELGCGASLARLAQKGIYIAAVVMTTGNSGTDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISALEDIIKNQMPSDVEIMRVYTMHDADRHQDHLAVYQASMVACRTIPQILGYETPSTWLSFMPQVFESVKEEYFTVKLAALKKHKSQERRDYMRHDRLRAVAQFRGQQVNSDLGEGFVIHKMIL
>NZ_CP025318.1|WP_001018416.1|3889232_3890195_-|taurine-ABC-transporter-substrate-binding-protein
MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPDAWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ
>NZ_CP025318.1|WP_104951280.1|3888452_3889220_-|taurine-ABC-transporter-ATP-binding-subunit
MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQMLKTVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFARRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS
>NZ_CP025318.1|WP_000114595.1|3887628_3888456_-|taurine-ABC-transporter-permease-TauC
MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAALQLISPLFLPPLQQVLAKLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPVIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
>NZ_CP025318.1|WP_001096705.1|3896777_3897317_-|DUF2058-domain-containing-protein
MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEENKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKIFVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAEEQDEDDPYADFKVPDDLMW
>NZ_CP025318.1|WP_000107624.1|3897418_3898630_-|3-(3-hydroxy-phenyl)propionate-transporter-MhpT
MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQAFALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWDFPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGFAGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQAAPPLRALFAPETATATLLLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDKLRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSSQIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMSRRSRMQPCADA
>NZ_CP025318.1|WP_001013499.1|3898805_3899819_-|4-hydroxy-2-oxovalerate-aldolase
MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLRNNK
>NZ_CP025318.1|WP_000044314.1|3899815_3900766_-|acetaldehyde-dehydrogenase
MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASKSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
>NZ_CP025318.1|WP_000160734.1|3900762_3901572_-|2-keto-4-pentenoate-hydratase
MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHINVQYDVVQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNEIIPFSRVLQPRIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNASCGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASLGEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS
>NZ_CP025318.1|WP_000121898.1|3901581_3902448_-|2-hydroxy-6-oxonona-2,4-dienedioate-hydrolase
MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQLDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFLARP
>NZ_CP025318.1|WP_000543459.1|3902465_3903410_-|3-carboxyethylcatechol-2,3-dioxygenase
MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGRFTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISTFGNWRSEGRYYRPIPEWIAGFGSLSARTEN
>NZ_CP025318.1|WP_001007449.1|3903411_3905076_-|bifunctional-3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic-acid-hydroxylase
MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKLIDYPRAIGIDDEALRTMQSVGLVENVLPHTTPWHAMRFLTPKGRCFADIQPMTDEFGWPRRNAFIQPQVDAVMLEGLSRFPNVRCLFARELEAFSQQNDEVTLHLKTAEGQRETVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDALLDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMRFKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCNPLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNASLVVMRPDRFVAATAIPQTLGNTLNKLASVMTLTRPDADVSVEKVA
>NZ_CP025318.1|WP_001316894.1|3905152_3906100_+|DNA-binding-transcriptional-activator-MhpR
MIFYCALSIGRVFSATIKTCPNVHQVHNVVLTIEMSINMQNNEQTEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLHRTTVRRLLETLQEEGYVRRSPSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLREVVWPTDVSTLDVDAMVVRETTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQERKELIEMLAARPGDDYQLAREPLKLQAILARARKEGYGQNYRGWDQEEKIASIAVPLRSEQRVIGCLNLVYMASAMTIEQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHLR
>NZ_CP025318.1|WP_000805910.1|3906176_3907259_+|LacI-family-DNA-binding-transcriptional-regulator
MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLIINYPLDDQDATAVEAACANVPALFLDVSDQTPINSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLARQVSRLESGQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP025318_5	5.1\|3057178\|40\|NZ_CP025318\|CRISPRCasFinder	3057178-3057217	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
NZ_CP025318_4	4.1\|2265848\|38\|NZ_CP025318\|CRISPRCasFinder	2265848-2265885	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_CP034578	Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08E, complete sequence	2106-2137	6	0.812
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_AP017930	Lactobacillus sakei subsp. sakei DSM 20017 = JCM 1157 strain LT-13 plasmid pLs13-a, complete sequence	4021-4052	6	0.812
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_CP043525	Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96 plasmid pSD96_01, complete sequence	3312-3343	6	0.812
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_CP014889	Lactobacillus backii strain TMW 1.1991 plasmid pL11991-8, complete sequence	1082-1113	6	0.812
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NC_015860	Lactococcus lactis subsp. lactis plasmid pIL1, complete sequence	3081-3112	6	0.812
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_AP022342	Enterococcus faecium strain KUHS13 plasmid pKO1, complete sequence	143632-143663	6	0.812
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_CP044372	Klebsiella pneumoniae strain 2018C01-046 plasmid p2018C01-046-4, complete sequence	5474-5505	6	0.812
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_MG674581	Enterococcus faecium strain HL1 plasmid pHLSA, complete sequence	148696-148727	6	0.812
NZ_CP025318_2	2.19\|1093754\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1093754-1093785	32	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	555773-555804	7	0.781
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229180-229234	7	0.873
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229281-229335	7	0.873
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239674-239728	7	0.873
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239775-239829	7	0.873
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230586-230640	7	0.873
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230687-230741	7	0.873
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211556-211610	7	0.873
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211657-211711	7	0.873
NZ_CP025318_2	2.23\|1093998\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1093998-1094029	32	NZ_CP050081	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence	41842-41873	8	0.75
NZ_CP025318_2	2.23\|1093998\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1093998-1094029	32	NZ_CP049731	Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence	41837-41868	8	0.75
NZ_CP025318_2	2.23\|1093998\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1093998-1094029	32	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	57043-57074	8	0.75
NZ_CP025318_2	2.23\|1093998\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1093998-1094029	32	NZ_CP053206	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence	41706-41737	8	0.75
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	MK064565	Sulfolobales Beppu rod-shaped virus 1 clone D, complete genome	8044-8075	8	0.75
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229382-229436	8	0.855
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239876-239930	8	0.855
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230788-230842	8	0.855
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211758-211812	8	0.855
NZ_CP025318_2	2.9\|1093997\|33\|NZ_CP025318\|PILER-CR	1093997-1094029	33	NZ_CP050081	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence	41842-41874	9	0.727
NZ_CP025318_2	2.9\|1093997\|33\|NZ_CP025318\|PILER-CR	1093997-1094029	33	NZ_CP049731	Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence	41837-41869	9	0.727
NZ_CP025318_2	2.9\|1093997\|33\|NZ_CP025318\|PILER-CR	1093997-1094029	33	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	57043-57075	9	0.727
NZ_CP025318_2	2.9\|1093997\|33\|NZ_CP025318\|PILER-CR	1093997-1094029	33	NZ_CP053206	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence	41706-41738	9	0.727
NZ_CP025318_2	2.20\|1093815\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1093815-1093846	32	CP024913	Cyanobacterium sp. HL-69 plasmid pCHL69-1, complete sequence	8579-8610	9	0.719
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	145876-145907	9	0.719
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	156592-156623	9	0.719
NZ_CP025318_3	3.2\|1109614\|32\|NZ_CP025318\|PILER-CR,CRISPRCasFinder,CRT	1109614-1109645	32	MN694366	Marine virus AFVG_250M1050, complete genome	2162-2193	9	0.719
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87169-87223	9	0.836
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	158418-158472	9	0.836
NZ_CP025318_2	2.6\|1093814\|33\|NZ_CP025318\|PILER-CR	1093814-1093846	33	CP024913	Cyanobacterium sp. HL-69 plasmid pCHL69-1, complete sequence	8579-8611	10	0.697
NZ_CP025318_2	2.28\|1094303\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1094303-1094334	32	NZ_CP039902	Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence	33041-33072	10	0.688
NZ_CP025318_2	2.28\|1094303\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1094303-1094334	32	NZ_CP039893	Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence	217865-217896	10	0.688
NZ_CP025318_2	2.28\|1094303\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1094303-1094334	32	NZ_KY000025	Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence	208000-208031	10	0.688
NZ_CP025318_2	2.28\|1094303\|32\|NZ_CP025318\|CRISPRCasFinder,CRT	1094303-1094334	32	NZ_KY000029	Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence	208000-208031	10	0.688
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229079-229133	10	0.818
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239573-239627	10	0.818
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230485-230539	10	0.818
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211455-211509	10	0.818
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	194092-194146	11	0.8
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	204586-204640	11	0.8
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	195420-195474	11	0.8
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	176375-176429	11	0.8
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	27377-27431	11	0.8
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	14103-14157	11	0.8
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	194185-194239	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	194278-194332	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	204679-204733	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	204772-204826	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	195513-195567	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	195606-195660	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	176468-176522	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	176561-176615	12	0.782
NZ_CP025318_7	7.1\|3896657\|55\|NZ_CP025318\|CRISPRCasFinder	3896657-3896711	55	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	27278-27332	12	0.782

1. spacer 5.1|3057178|40|NZ_CP025318|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 4.1|2265848|38|NZ_CP025318|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

3. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034578 (Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08E, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

4. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP017930 (Lactobacillus sakei subsp. sakei DSM 20017 = JCM 1157 strain LT-13 plasmid pLs13-a, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

5. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043525 (Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96 plasmid pSD96_01, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

6. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014889 (Lactobacillus backii strain TMW 1.1991 plasmid pL11991-8, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

7. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NC_015860 (Lactococcus lactis subsp. lactis plasmid pIL1, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

8. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022342 (Enterococcus faecium strain KUHS13 plasmid pKO1, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

9. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044372 (Klebsiella pneumoniae strain 2018C01-046 plasmid p2018C01-046-4, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

10. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG674581 (Enterococcus faecium strain HL1 plasmid pHLSA, complete sequence) position: , mismatch: 6, identity: 0.812

caaaaaaatagattggaaaacatttagattca-	CRISPR spacer
taaaaaaataaattggaaaaaattt-gatgaat	Protospacer
.*********.********* **** ***  *

11. spacer 2.19|1093754|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

-gtctgtgatggcctgctcgtgagtccgcggcg	CRISPR spacer
cgcgtg-gatggcctgctcgtcagttcgcgcct	Protospacer
 *. ** ************** ***.**** *

12. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgcg	Protospacer
 ********************************************.  * ** *.

13. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacgggtggcgcg	Protospacer
 ********************************************.  * ** *.

14. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgcg	Protospacer
 ********************************************.  * ** *.

15. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacgggtggcgcg	Protospacer
 ********************************************.  * ** *.

16. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgcg	Protospacer
 ********************************************.  * ** *.

17. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacgggtggcgcg	Protospacer
 ********************************************.  * ** *.

18. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgcg	Protospacer
 ********************************************.  * ** *.

19. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.873

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtgaacgccttatccggcctacgggtggcgcg	Protospacer
 ********************************************.  * ** *.

20. spacer 2.23|1093998|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_CP050081 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence) position: , mismatch: 8, identity: 0.75

ctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
ttccagaccaatcttctggcgctcaacgccgg	Protospacer
.**.   .**.** ******************

21. spacer 2.23|1093998|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_CP049731 (Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence) position: , mismatch: 8, identity: 0.75

ctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
ttccagaccaatcttctggcgctcaacgccgg	Protospacer
.**.   .**.** ******************

22. spacer 2.23|1093998|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 8, identity: 0.75

ctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
ttccagaccaatcttctggcgctcaacgccgg	Protospacer
.**.   .**.** ******************

23. spacer 2.23|1093998|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_CP053206 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence) position: , mismatch: 8, identity: 0.75

ctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
ttccagaccaatcttctggcgctcaacgccgg	Protospacer
.**.   .**.** ******************

24. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to MK064565 (Sulfolobales Beppu rod-shaped virus 1 clone D, complete genome) position: , mismatch: 8, identity: 0.75

caaaaaaatagattggaaaacatttagattca---	CRISPR spacer
acaaaaaagagactggaaaacattt---tttaatt	Protospacer
  ****** ***.************   **.*

25. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.855

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtaaacgccttatccggcctacggatggcgcg	Protospacer
 ************************.*******************.  * ** *.

26. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.855

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtaaacgccttatccggcctacggatggcgcg	Protospacer
 ************************.*******************.  * ** *.

27. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.855

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtaaacgccttatccggcctacggatggcgcg	Protospacer
 ************************.*******************.  * ** *.

28. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.855

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
tgcgcacgactgccggatgcggcgtaaacgccttatccggcctacggatggcgcg	Protospacer
 ************************.*******************.  * ** *.

29. spacer 2.9|1093997|33|NZ_CP025318|PILER-CR matches to NZ_CP050081 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b5, complete sequence) position: , mismatch: 9, identity: 0.727

gctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
cttccagaccaatcttctggcgctcaacgccgg	Protospacer
 .**.   .**.** ******************

30. spacer 2.9|1093997|33|NZ_CP025318|PILER-CR matches to NZ_CP049731 (Rhizobium leguminosarum strain A1 plasmid pRL12, complete sequence) position: , mismatch: 9, identity: 0.727

gctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
cttccagaccaatcttctggcgctcaacgccgg	Protospacer
 .**.   .**.** ******************

31. spacer 2.9|1093997|33|NZ_CP025318|PILER-CR matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 9, identity: 0.727

gctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
tttccagaccaatcttctggcgctcaacgccgg	Protospacer
 .**.   .**.** ******************

32. spacer 2.9|1093997|33|NZ_CP025318|PILER-CR matches to NZ_CP053206 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1D, complete sequence) position: , mismatch: 9, identity: 0.727

gctctttctcagtcatctggcgctcaacgccgg	CRISPR spacer
cttccagaccaatcttctggcgctcaacgccgg	Protospacer
 .**.   .**.** ******************

33. spacer 2.20|1093815|32|NZ_CP025318|CRISPRCasFinder,CRT matches to CP024913 (Cyanobacterium sp. HL-69 plasmid pCHL69-1, complete sequence) position: , mismatch: 9, identity: 0.719

aattttttatcctcataaacagcctcagaaaa	CRISPR spacer
tcatttttaccctcattaacagcctcatccat	Protospacer
   ******.****** **********   *

34. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 9, identity: 0.719

caaaaaaatagattggaaaacatttagattca	CRISPR spacer
agataaaatagattataaaacatttagaagac	Protospacer
 .* **********. ************

35. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 9, identity: 0.719

caaaaaaatagattggaaaacatttagattca	CRISPR spacer
agataaaatagattataaaacatttagaagac	Protospacer
 .* **********. ************

36. spacer 3.2|1109614|32|NZ_CP025318|PILER-CR,CRISPRCasFinder,CRT matches to MN694366 (Marine virus AFVG_250M1050, complete genome) position: , mismatch: 9, identity: 0.719

caaaaaaatagattggaaaacatttagattca	CRISPR spacer
caaaaaaatagatttgaacacataaaaggcaa	Protospacer
************** *** ****  *.. . *

37. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 9, identity: 0.836

ggcgca-cgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca--	CRISPR spacer
-gtgcaccgaatgccggatgcggcgtgaacgccttatccgtcctacaat--gcctgat	Protospacer
 *.*** *** ***************************** ****** *  ***..

38. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 9, identity: 0.836

ggcgcacgactgccggatgcggcgtgaacgccttatccggc--ctacacttcgccca	CRISPR spacer
ggcgcacaattgccggatgcggcgtgaacgccttatccgcctaccgaactgcgcc--	Protospacer
*******.*.***************************** *  *.. *** ****

39. spacer 2.6|1093814|33|NZ_CP025318|PILER-CR matches to CP024913 (Cyanobacterium sp. HL-69 plasmid pCHL69-1, complete sequence) position: , mismatch: 10, identity: 0.697

gaattttttatcctcataaacagcctcagaaaa	CRISPR spacer
ctcatttttaccctcattaacagcctcatccat	Protospacer
    ******.****** **********   *

40. spacer 2.28|1094303|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_CP039902 (Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

41. spacer 2.28|1094303|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_CP039893 (Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

42. spacer 2.28|1094303|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_KY000025 (Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

43. spacer 2.28|1094303|32|NZ_CP025318|CRISPRCasFinder,CRT matches to NZ_KY000029 (Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

44. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 10, identity: 0.818

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ccagcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgtg	Protospacer
   ******************************************.  * ** ..

45. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 10, identity: 0.818

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ccagcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgtg	Protospacer
   ******************************************.  * ** ..

46. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 10, identity: 0.818

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ccagcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgtg	Protospacer
   ******************************************.  * ** ..

47. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 10, identity: 0.818

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ccagcacgactgccggatgcggcgtgaacgccttatccggcctacggatggcgtg	Protospacer
   ******************************************.  * ** ..

48. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.8

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgaatggcgca	Protospacer
    *** *.***********************************.  * ** **

49. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.8

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgaatggcgca	Protospacer
    *** *.***********************************.  * ** **

50. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.8

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgaatggcgca	Protospacer
    *** *.***********************************.  * ** **

51. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.8

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgaatggcgca	Protospacer
    *** *.***********************************.  * ** **

52. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 11, identity: 0.8

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ggcgcacaaccgccggatgcggcgtgaacgccttatccggcctacgggtgagtgc	Protospacer
*******.**.**********************************.  * . .

53. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 11, identity: 0.8

-ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
aggcgt-tgattgccggatgcggcgtaaacgccttatccggcctacattcggcaag	Protospacer
 ****. .**.***************.********************.*. **  .

54. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgccaccactgccggatgcggcgtggacgccttatccggcctacgagtggcgcg	Protospacer
    *** ******************.******************.  * ** *.

55. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgagtggcgcg	Protospacer
    *** *.***********************************.  * ** *.

56. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgccaccactgccggatgcggcgtggacgccttatccggcctacgagtggcgcg	Protospacer
    *** ******************.******************.  * ** *.

57. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgagtggcgcg	Protospacer
    *** *.***********************************.  * ** *.

58. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgccaccactgccggatgcggcgtggacgccttatccggcctacgagtggcgcg	Protospacer
    *** ******************.******************.  * ** *.

59. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgagtggcgcg	Protospacer
    *** *.***********************************.  * ** *.

60. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgccaccactgccggatgcggcgtggacgccttatccggcctacgagtggcgcg	Protospacer
    *** ******************.******************.  * ** *.

61. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ttgtcaccattgccggatgcggcgtgaacgccttatccggcctacgagtggcgcg	Protospacer
    *** *.***********************************.  * ** *.

62. spacer 7.1|3896657|55|NZ_CP025318|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 12, identity: 0.782

ggcgcacgactgccggatgcggcgtgaacgccttatccggcctacacttcgccca	CRISPR spacer
ggtacacaaccgccggatgcggcgtgaacgccttatccggcctacgggtgagcac	Protospacer
**..***.**.**********************************.  * . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1126089 : 1134006

Escherichia_phage(83.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001278994.1\|1126089_1126728_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590392.1\|1126724_1127987_-	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_000847985.1\|1127983_1128892_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_001297141.1\|1129087_1129855_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_001141314.1\|1130682_1131339_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	1.1e-50	47.9
WP_104951056.1\|1131444_1134006_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.0e-30	20.7

DBSCAN-SWA_2

1170796 : 1275647

101

Shigella_phage(36.96%)

transposase,tRNA,plate,tail,head,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000047176.1\|1170796_1173427_+\|tRNA	alanine--tRNA ligase	A0A2K9L1X7	Tupanvirus	5.5e-80	38.6
WP_000906486.1\|1173661_1173847_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	4.9e-12	66.7
WP_000273309.1\|1175439_1176006_+	fructose-1-phosphate/6-phosphogluconate phosphatase	NA	NA	NA	NA
WP_001287454.1\|1176002_1176431_+	DedA family protein	NA	NA	NA	NA
WP_000611804.1\|1176503_1178060_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_001130207.1\|1178209_1178725_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_001295176.1\|1178788_1180327_-	multidrug efflux MFS transporter permease subunit EmrB	NA	NA	NA	NA
WP_001295175.1\|1180343_1181516_-	multidrug efflux MFS transporter periplasmic adaptor subunit EmrA	NA	NA	NA	NA
WP_000378442.1\|1181642_1182173_-	multidrug efflux transporter EmrAB transcriptional repressor EmrR	NA	NA	NA	NA
WP_000119763.1\|1182263_1182599_-	L-valine transporter subunit YgaH	NA	NA	NA	NA
WP_000445658.1\|1182588_1183326_-	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_000165699.1\|1183449_1184634_-	MFS transporter	NA	NA	NA	NA
WP_001216527.1\|1184925_1185918_-	glycine betaine/L-proline ABC transporter substrate-binding protein ProX	NA	NA	NA	NA
WP_000774996.1\|1185974_1187039_-	glycine betaine/L-proline ABC transporter permease ProW	NA	NA	NA	NA
WP_000985494.1\|1187031_1188234_-	glycine betaine/L-proline ABC transporter ATP-binding protein ProV	G3M9Y6	Bacillus_virus	4.9e-28	39.4
WP_104951060.1\|1189557_1191702_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.0e-193	47.8
WP_000080944.1\|1191674_1192085_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	2.7e-18	44.4
WP_001223227.1\|1192081_1192327_-	glutaredoxin-like protein NrdH	Q5K5J3	Oenococcus_phage	1.8e-06	35.3
WP_001295174.1\|1192574_1192904_-	DUF883 domain-containing protein	NA	NA	NA	NA
WP_000281320.1\|1193055_1193400_+	YgaC family protein	NA	NA	NA	NA
WP_000492656.1\|1193435_1193885_-	L-alanine exporter AlaE	NA	NA	NA	NA
WP_000115383.1\|1194552_1194957_+	DNA-binding protein StpA	NA	NA	NA	NA
WP_001229468.1\|1195003_1195528_-	thiosulfate sulfurtransferase YgaP	NA	NA	NA	NA
WP_000137280.1\|1195537_1195837_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000508177.1\|1196019_1196178_+	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_000522424.1\|1196261_1196711_+	potassium binding protein Kbp	A0A090DBR9	Clostridium_phage	2.0e-06	39.5
WP_000156811.1\|1196711_1197374_-	DNA-binding transcriptional regulator CsiR	NA	NA	NA	NA
WP_104951061.1\|1197394_1198795_-	GABA permease	NA	NA	NA	NA
WP_000097641.1\|1199105_1200386_-	4-aminobutyrate--2-oxoglutarate transaminase	A0A1V0SKB7	Klosneuvirus	2.4e-33	30.1
WP_104951062.1\|1200399_1201848_-	NADP-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000271965.1\|1201870_1203139_-	L-2-hydroxyglutarate oxidase	NA	NA	NA	NA
WP_001315804.1\|1203157_1204135_-	carbon starvation induced protein CsiD	NA	NA	NA	NA
WP_089645654.1\|1204469_1206722_-	hypothetical protein	NA	NA	NA	NA
WP_000340075.1\|1209866_1210124_+	hypothetical protein	A0A1S6L009	Salmonella_phage	1.2e-05	69.2
WP_000927517.1\|1210209_1210329_+	hypothetical protein	NA	NA	NA	NA
WP_085947772.1\|1210833_1212047_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.3e-100	57.1
WP_001193631.1\|1213102_1213753_+\|head,protease	HK97 family phage prohead protease	U5P4H2	Shigella_phage	2.5e-119	100.0
WP_000257507.1\|1213767_1214973_+\|capsid	phage major capsid protein	M1FPN2	Enterobacteria_phage	1.8e-224	100.0
WP_001297480.1\|1215022_1215223_+	hypothetical protein	S5FNU1	Shigella_phage	8.4e-26	97.0
WP_000927711.1\|1215225_1215549_+\|head,tail	phage gp6-like head-tail connector protein	U5P072	Shigella_phage	1.1e-56	99.1
WP_024215340.1\|1215545_1215956_+\|head	phage head closure protein	M1FJ87	Enterobacteria_phage	1.7e-73	97.1
WP_024215338.1\|1215930_1216437_+	hypothetical protein	M1FPE2	Enterobacteria_phage	8.9e-80	89.9
WP_024215336.1\|1216433_1216994_+	hypothetical protein	Q8SBH4	Shigella_phage	1.5e-104	98.9
WP_000497751.1\|1217002_1217173_+	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	9.3e-26	100.0
WP_104951063.1\|1217156_1218653_+\|tail	phage tail protein	S5FKL0	Shigella_phage	1.2e-276	99.0
WP_000090998.1\|1218652_1219009_+	hypothetical protein	U5P076	Shigella_phage	5.3e-63	100.0
WP_000661047.1\|1219008_1219278_+\|tail	phage tail assembly protein	S5FNR3	Shigella_phage	3.5e-43	100.0
WP_104951064.1\|1219419_1221252_+\|tail	phage tail tape measure protein	Q8SBG9	Shigella_phage	1.2e-299	97.2
WP_024215333.1\|1221936_1223265_+	DNA circularization protein	Q8SBG8	Shigella_phage	1.6e-245	98.6
WP_104951065.1\|1223261_1224341_+\|plate	baseplate protein	U5P0H6	Shigella_phage	9.1e-207	99.7
WP_001259079.1\|1224340_1224889_+\|plate	phage baseplate assembly protein	Q8SBG6	Shigella_phage	2.3e-97	100.0
WP_032254860.1\|1224888_1225314_+\|tail	phage tail protein	U5P0R9	Shigella_phage	5.7e-80	98.6
WP_000785311.1\|1225300_1226359_+\|plate	baseplate J/gp47 family protein	Q8SBG4	Shigella_phage	8.1e-200	98.6
WP_024215329.1\|1226349_1226934_+	YmfQ family protein	O22003	Shigella_phage	4.1e-113	99.5
WP_104951344.1\|1227204_1227600_+	hypothetical protein	O22004	Shigella_phage	3.1e-11	38.8
WP_000782984.1\|1227596_1228016_+\|tail	tail assembly chaperone	M1SNQ2	Escherichia_phage	3.8e-36	64.7
WP_001145385.1\|1228390_1228795_-	hypothetical protein	M1FN94	Enterobacteria_phage	4.7e-15	42.3
WP_000905033.1\|1228825_1229392_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	3.8e-87	86.8
WP_000046133.1\|1229534_1230707_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.3e-203	90.0
WP_001207660.1\|1230716_1231232_+\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	2.1e-89	95.3
WP_001281009.1\|1231286_1231589_+\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	5.3e-40	89.0
WP_000763311.1\|1231603_1231723_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.8e-13	87.2
WP_001282809.1\|1231715_1234793_+\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	69.6
WP_000980400.1\|1234789_1235275_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	4.8e-67	80.6
WP_001011792.1\|1235271_1236372_+	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	7.6e-177	88.5
WP_000980502.1\|1236440_1236659_+	hypothetical protein	Q53ZE7	Salmonella_virus	2.2e-27	76.4
WP_000391796.1\|1236685_1237168_-	hypothetical protein	Q19UP0	Mannheimia_phage	4.6e-17	34.3
WP_000162574.1\|1237868_1238351_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_000600190.1\|1238482_1238959_+	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_001117838.1\|1238948_1239239_+	RnfH family protein	NA	NA	NA	NA
WP_001203437.1\|1239300_1239642_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_089645710.1\|1239790_1241452_-	DNA repair protein RecN	NA	NA	NA	NA
WP_001059169.1\|1241537_1242416_-	NAD(+) kinase	NA	NA	NA	NA
WP_001296310.1\|1242538_1243132_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_077221315.1\|1243186_1244473_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001338897.1\|1244493_1245285_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_000460035.1\|1245451_1246813_+	signal recognition particle protein	NA	NA	NA	NA
WP_000256450.1\|1246949_1247198_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_000043335.1\|1247216_1247765_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000264777.1\|1247795_1248563_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000065253.1\|1248604_1248952_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_000589828.1\|1249028_1249511_-	OmpA family protein	NA	NA	NA	NA
WP_000969032.1\|1249526_1250753_-	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_001212391.1\|1250742_1251261_-	YfiR family protein	NA	NA	NA	NA
WP_000976004.1\|1251410_1251776_-	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_089645709.1\|1251985_1253056_+	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	1.2e-89	50.9
WP_000225221.1\|1253066_1254188_+	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_000200100.1\|1254230_1255391_-	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_001700969.1\|1255489_1255537_-	hypothetical protein	NA	NA	NA	NA
WP_000178456.1\|1255640_1255982_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_000197686.1\|1256252_1256990_-	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_104951066.1\|1257124_1258105_+	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000040115.1\|1258101_1258833_+	polyphenol oxidase	NA	NA	NA	NA
WP_001235102.1\|1258962_1261536_+	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000230376.1\|1267391_1268690_+	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	1.3e-45	32.2
WP_001300818.1\|1268686_1269010_-	YfiM family lipoprotein	NA	NA	NA	NA
WP_000949265.1\|1269055_1270411_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_000082964.1\|1270524_1273185_-	protein lysine acetyltransferase	NA	NA	NA	NA
WP_000138184.1\|1273216_1273915_-	DTW domain-containing protein	NA	NA	NA	NA
WP_001098726.1\|1273983_1274403_-	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_000997403.1\|1274609_1275647_+\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA

DBSCAN-SWA_3

1659713 : 1729590

Enterobacteria_phage(48.0%)

lysis,terminase,transposase,portal,tail,integrase,protease,capsid

attL 1676519:1676544|attR 1684765:1684790

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000849209.1\|1659713_1660202_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_089645496.1\|1660609_1661104_+	ferredoxin-type protein NapF	NA	NA	NA	NA
WP_000557378.1\|1661093_1661357_+	chaperone NapD	NA	NA	NA	NA
WP_000778057.1\|1661353_1663840_+	periplasmic nitrate reductase subunit alpha	NA	NA	NA	NA
WP_000091291.1\|1663846_1664542_+	ferredoxin-type protein NapG	NA	NA	NA	NA
WP_000013506.1\|1664528_1665392_+	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
WP_000835177.1\|1665388_1665838_+	nitrate reductase cytochrome c-type subunit	NA	NA	NA	NA
WP_000528376.1\|1665847_1666450_+	cytochrome c-type protein NapC	NA	NA	NA	NA
WP_001296826.1\|1666468_1667086_+	cytochrome c biogenesis heme-transporting ATPase CcmA	G3M9Y6	Bacillus_virus	2.5e-12	25.5
WP_000971730.1\|1667082_1667745_+	heme exporter protein CcmB	NA	NA	NA	NA
WP_001295447.1\|1667786_1668524_+	heme exporter protein CcmC	NA	NA	NA	NA
WP_000186540.1\|1668520_1668730_+	heme exporter protein CcmD	NA	NA	NA	NA
WP_001026422.1\|1668726_1669206_+	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_000982426.1\|1669202_1671146_+	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_000824439.1\|1671142_1671700_+	thiol:disulfide interchange protein DsbE	NA	NA	NA	NA
WP_001211587.1\|1671696_1672749_+	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_001113637.1\|1672783_1673431_-	nitrate/nitrite response regulator protein NarP	NA	NA	NA	NA
1676519:1676544	attL	NA	NA	NA	NA
WP_001369202.1\|1676811_1677735_-\|capsid	phage capsid protein	A0A0R6PHC6	Moraxella_phage	1.2e-13	24.9
WP_001229488.1\|1677897_1678386_-\|terminase	terminase small subunit	A0A0P0ZCQ9	Stx2-converting_phage	3.9e-24	41.7
WP_001018604.1\|1678513_1678675_-	hypothetical protein	NA	NA	NA	NA
WP_000391151.1\|1678678_1678873_-	hypothetical protein	NA	NA	NA	NA
WP_001080641.1\|1679003_1679249_-	hypothetical protein	NA	NA	NA	NA
WP_000833625.1\|1679450_1680851_-	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.6e-115	60.1
WP_000770163.1\|1680847_1681147_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_096954808.1\|1681152_1681386_-	hypothetical protein	NA	NA	NA	NA
WP_001204070.1\|1681387_1681609_-	hypothetical protein	NA	NA	NA	NA
WP_001342316.1\|1681581_1681824_-	hypothetical protein	NA	NA	NA	NA
WP_021543716.1\|1681813_1682014_-	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_000387479.1\|1682757_1682964_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_000101718.1\|1683460_1684702_-\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	1.2e-98	43.1
WP_001136067.1\|1685404_1686172_+	hypothetical protein	NA	NA	NA	NA
1684765:1684790	attR	NA	NA	NA	NA
WP_001145023.1\|1686161_1686545_+	hypothetical protein	NA	NA	NA	NA
WP_000183538.1\|1687028_1687985_+	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_000741304.1\|1688122_1689301_-	recombinase	A0A2D1GN00	Marinobacter_phage	2.7e-31	30.6
WP_001096409.1\|1689303_1689513_-	hypothetical protein	NA	NA	NA	NA
WP_021548839.1\|1689574_1689790_-	hypothetical protein	K7PLX1	Enterobacteria_phage	3.7e-27	92.1
WP_001242718.1\|1689786_1690149_-	phage protein	K7PH61	Enterobacteria_phage	3.6e-67	99.2
WP_000008200.1\|1690139_1690676_-	5'-deoxynucleotidase	U5P0T3	Shigella_phage	4.3e-101	100.0
WP_000081287.1\|1690803_1691628_-	DUF2303 family protein	U5P439	Shigella_phage	6.0e-150	100.0
WP_000135680.1\|1691693_1692056_-	hypothetical protein	Q8SBF8	Shigella_phage	8.6e-61	100.0
WP_001020632.1\|1692758_1693451_-	helix-turn-helix transcriptional regulator	S5FUZ3	Shigella_phage	6.4e-121	96.5
WP_032198020.1\|1693548_1693809_+	helix-turn-helix transcriptional regulator	K7PJQ8	Enterobacteria_phage	7.1e-41	98.8
WP_032198019.1\|1693801_1694353_+	hypothetical protein	U5P4K1	Shigella_phage	3.8e-100	98.9
WP_001250272.1\|1694528_1694708_+	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_023993851.1\|1694697_1695654_+	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	6.1e-138	91.5
WP_104951090.1\|1695650_1696103_+	PerC family transcriptional regulator	U5P0U0	Shigella_phage	3.4e-75	95.3
WP_101973092.1\|1696142_1697356_-\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	1.0e-166	97.6
WP_001442792.1\|1697457_1698111_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	4.7e-126	98.6
WP_104951091.1\|1698107_1698434_+	LexA family transcriptional regulator	A0A291AWY9	Escherichia_phage	3.5e-53	98.1
WP_000767103.1\|1698430_1698820_+	RusA family crossover junction endodeoxyribonuclease	A5LH74	Enterobacteria_phage	1.0e-67	98.4
WP_104951092.1\|1698839_1699649_+	KilA-N domain-containing protein	Q8SBE6	Shigella_phage	1.1e-151	98.1
WP_032198014.1\|1699656_1700646_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.8e-193	98.5
WP_104021943.1\|1700660_1701026_+	antitermination protein Q	A5LH77	Enterobacteria_phage	3.8e-56	89.2
WP_137548549.1\|1701044_1701476_-	hypothetical protein	NA	NA	NA	NA
WP_032198010.1\|1701720_1702584_-	hypothetical protein	NA	NA	NA	NA
WP_000917724.1\|1702859_1703063_+	hypothetical protein	A0A291AWX6	Escherichia_phage	6.1e-32	100.0
WP_000799656.1\|1703213_1704266_+	site-specific DNA-methyltransferase	A5LH81	Enterobacteria_phage	2.7e-208	100.0
WP_000839596.1\|1704333_1704549_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_021535405.1\|1704548_1705046_+	lysozyme	A5LH83	Enterobacteria_phage	7.1e-90	97.6
WP_000088939.1\|1705042_1705504_+\|lysis	lysis protein	A0A0K2FJD0	Enterobacteria_phage	7.6e-46	66.4
WP_032198009.1\|1705543_1705783_+	hypothetical protein	NA	NA	NA	NA
WP_000349509.1\|1706462_1706954_+	DUF1441 family protein	A0A291AWV8	Escherichia_phage	1.3e-72	87.2
WP_104951093.1\|1706953_1709056_+\|terminase	phage terminase large subunit family protein	A0A291AWY5	Escherichia_phage	0.0e+00	97.1
WP_001072975.1\|1709052_1709265_+	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_072652320.1\|1709192_1710740_+\|portal	phage portal protein	K7PJP3	Enterobacteria_phage	2.2e-283	99.8
WP_096845279.1\|1710717_1712745_+\|protease	Clp protease ClpP	A5LH30	Enterobacteria_phage	0.0e+00	99.8
WP_001097050.1\|1712831_1713155_+	DUF2190 family protein	A0A291AWX2	Escherichia_phage	8.5e-52	100.0
WP_001283153.1\|1713147_1713423_+	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	2.3e-45	100.0
WP_000677108.1\|1713434_1714013_+\|tail	phage tail protein	A5LH33	Enterobacteria_phage	7.2e-102	99.5
WP_001079398.1\|1714009_1714411_+\|tail	tail protein	A0A291AWY2	Escherichia_phage	8.3e-73	100.0
WP_104951094.1\|1714422_1715166_+\|tail	phage tail protein	A0A291AWU6	Escherichia_phage	7.3e-131	98.4
WP_001370402.1\|1715226_1715613_+\|tail	phage minor tail protein G	A0A291AWW5	Escherichia_phage	4.9e-62	96.1
WP_001161009.1\|1715621_1715951_+\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.6e-56	100.0
WP_104951095.1\|1715922_1718997_+\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	0.0e+00	94.8
WP_000847325.1\|1718993_1719323_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	7.6e-56	97.2
WP_104951096.1\|1719322_1720021_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.0e-130	96.6
WP_104951097.1\|1720026_1720770_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.1e-142	93.5
WP_104951098.1\|1720667_1721315_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	1.9e-111	97.2
WP_104951099.1\|1721375_1724873_+	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	97.4
WP_104951100.1\|1724943_1725543_+	Ail/Lom family outer membrane beta-barrel protein	A5LH44	Enterobacteria_phage	4.1e-108	97.0
WP_104951345.1\|1725607_1729006_+	short-chain fatty acid transporter	X2KTY7	Enterobacteria_phage	1.8e-11	35.5
WP_104951101.1\|1729005_1729590_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	6.0e-104	95.4

DBSCAN-SWA_4

1801452 : 1810894

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569313.1\|1801452_1802379_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	3.1e-22	30.3
WP_000783120.1\|1802383_1803115_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|1803095_1803203_-	protein YohO	NA	NA	NA	NA
WP_001240401.1\|1803262_1803994_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|1804215_1805901_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|1805897_1806617_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295430.1\|1806663_1807134_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_001295429.1\|1807174_1807636_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001317947.1\|1807760_1809761_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.1
WP_001292774.1\|1809757_1810894_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7

DBSCAN-SWA_5

2339398 : 2409312

Enterobacteria_phage(35.0%)

terminase,portal,tail,head,integrase,protease,holin,capsid

attL 2348002:2348016|attR 2380437:2380451

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001260840.1\|2339398_2340220_-\|protease	serine protease	NA	NA	NA	NA
WP_000233090.1\|2340319_2340403_-	hypothetical protein	NA	NA	NA	NA
WP_000743960.1\|2340495_2340831_-	acid shock protein	NA	NA	NA	NA
WP_000091819.1\|2341227_2342481_-	MFS transporter	NA	NA	NA	NA
WP_001019530.1\|2342587_2343481_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000225276.1\|2343615_2344836_+	DNA-binding transcriptional repressor Mlc	NA	NA	NA	NA
WP_000919231.1\|2344960_2345656_+	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_071597725.1\|2345608_2346901_-	voltage-gated ClC-type chloride channel ClcB	NA	NA	NA	NA
WP_000148710.1\|2347058_2347673_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	8.7e-29	36.3
WP_000526492.1\|2347715_2348570_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
2348002:2348016	attL	NA	NA	NA	NA
WP_000213028.1\|2348571_2349189_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	9.5e-76	59.6
WP_001433342.1\|2349199_2351623_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	2.8e-208	48.6
WP_000041556.1\|2351683_2354110_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	7.7e-214	49.0
WP_001307224.1\|2354308_2354614_-	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_077825778.1\|2354721_2355432_+	YnfC family lipoprotein	NA	NA	NA	NA
WP_104951147.1\|2355434_2355995_-	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_000705211.1\|2356029_2356371_-	DUF1283 family protein	NA	NA	NA	NA
WP_000598292.1\|2356505_2356832_+	YnfA family protein	A0A218MNG8	uncultured_virus	9.9e-24	55.6
WP_001295394.1\|2357037_2358252_+	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	1.4e-46	29.0
WP_000836054.1\|2358263_2359283_+	Zn-dependent oxidoreductase	E3SJ82	Synechococcus_phage	7.4e-17	26.2
WP_072095801.1\|2359340_2359451_+	transporter	NA	NA	NA	NA
WP_001206147.1\|2359470_2360766_-\|integrase	site-specific integrase	B6DZ48	Enterobacteria_phage	1.3e-154	62.2
WP_001368608.1\|2360785_2361022_-	excisionase family protein	S4TND0	Salmonella_phage	6.1e-15	50.7
WP_104951148.1\|2361109_2363554_-	exonuclease	V5UQJ3	Shigella_phage	2.2e-176	58.5
WP_000092782.1\|2363646_2363835_-	DUF1482 family protein	NA	NA	NA	NA
WP_104951149.1\|2363831_2364020_-	cell division inhibitor	NA	NA	NA	NA
WP_001133037.1\|2364584_2364794_+	hypothetical protein	NA	NA	NA	NA
WP_000394548.1\|2364794_2365433_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_000379563.1\|2365444_2365597_-	DUF1391 family protein	M4QQ57	Salicola_phage	1.0e-07	55.3
WP_000362153.1\|2365862_2366282_-	hypothetical protein	K7PK07	Enterobacteria_phage	8.8e-25	65.1
WP_000391950.1\|2366382_2366664_+	hypothetical protein	K7PHA1	Enterobacteria_phage	6.5e-24	72.6
WP_000693888.1\|2366647_2367073_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000095667.1\|2367095_2368049_+	DNA-binding protein	U5P0A0	Shigella_phage	5.2e-73	51.7
WP_000790456.1\|2368055_2368796_+	ATP-binding protein	V5UQI5	Shigella_phage	7.8e-117	85.6
WP_052915473.1\|2368825_2369596_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.1e-84	66.8
WP_001118161.1\|2369611_2370007_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.0e-30	51.4
WP_104951348.1\|2370063_2370420_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	1.4e-55	94.1
WP_104951150.1\|2370468_2370651_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	2.9e-25	86.4
WP_001278450.1\|2371418_2371523_+	hypothetical protein	NA	NA	NA	NA
WP_000902693.1\|2371712_2371925_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	6.8e-26	92.9
WP_072128871.1\|2372092_2372371_+	hypothetical protein	I6PCV7	Cronobacter_phage	3.7e-11	46.9
WP_001265167.1\|2372372_2373422_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.9e-108	53.7
WP_000904171.1\|2373434_2373809_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	4.2e-34	62.7
WP_000762902.1\|2373805_2374627_+	hypothetical protein	K7P7B9	Enterobacteria_phage	2.8e-83	61.9
WP_000917735.1\|2374853_2375051_+	hypothetical protein	S5MQK8	Escherichia_phage	1.8e-28	98.5
WP_104951151.1\|2375201_2376260_+	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	9.2e-188	89.9
WP_044805529.1\|2376702_2377134_+	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	6.0e-69	98.6
WP_104951152.1\|2377705_2379307_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	1.7e-310	98.9
WP_000411809.1\|2379795_2380002_+\|holin	holin	Q6H9V8	Enterobacteria_phage	2.4e-31	100.0
WP_000731236.1\|2380006_2380351_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-58	100.0
WP_000992167.1\|2380401_2380935_+	lysozyme	A0A0N7KZF9	Stx2-converting_phage	7.4e-101	98.9
2380437:2380451	attR	NA	NA	NA	NA
WP_012578895.1\|2381453_2381639_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	2.7e-18	98.4
WP_000453587.1\|2382142_2382688_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_104951153.1\|2382662_2384588_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	98.9
WP_000198153.1\|2384584_2384791_+\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001415980.1\|2384787_2386389_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	2.3e-307	98.5
WP_033805059.1\|2386369_2387689_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	2.2e-231	97.7
WP_047088185.1\|2387698_2388031_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	9.3e-54	97.3
WP_000063258.1\|2388086_2389112_+\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	5.1e-191	98.8
WP_000158897.1\|2389153_2389549_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.4e-56	93.9
WP_000752994.1\|2389560_2389914_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.0e-63	100.0
WP_000975099.1\|2389925_2390504_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
WP_000683137.1\|2390500_2390896_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	3.7e-65	92.4
WP_000235098.1\|2390903_2391656_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	4.9e-135	99.2
WP_094312264.1\|2391669_2392074_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	1.1e-64	92.9
WP_000533440.1\|2392100_2392514_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_024017784.1\|2392494_2395107_+\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	96.2
WP_000847298.1\|2395103_2395433_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_104951154.1\|2395432_2396131_+\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	8.1e-132	98.7
WP_104951155.1\|2396141_2396885_+\|tail	phage tail protein	Q9EYE4	Enterobacteria_phage	7.3e-147	97.2
WP_158672591.1\|2396830_2397460_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	2.0e-105	93.8
WP_096939734.1\|2401245_2401845_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	1.8e-108	97.5
WP_104951157.1\|2401909_2403109_+\|tail	phage tail protein	A0A0P0ZDE7	Stx2-converting_phage	4.7e-79	97.1
WP_001023452.1\|2403110_2403380_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	6.4e-45	100.0
WP_000491545.1\|2403520_2404396_+	hypothetical protein	A0A0P0ZCT1	Stx2-converting_phage	7.2e-162	99.7
WP_001121225.1\|2404620_2405271_-	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_096245710.1\|2405866_2406181_-	DinI-like family protein	Q687E4	Enterobacteria_phage	1.3e-25	81.9
WP_000347482.1\|2406240_2407524_+	MHS family MFS transporter	NA	NA	NA	NA
WP_047090288.1\|2407612_2409073_+	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	3.6e-41	29.6
WP_000214712.1\|2409108_2409312_-	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2

DBSCAN-SWA_6

2691455 : 2763479

Enterobacteria_phage(26.67%)

terminase,transposase,holin,tail,integrase,protease,capsid

attL 2705232:2705259|attR 2763616:2763643

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000422045.1\|2691455_2692505_-\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5
WP_000559281.1\|2692724_2693483_+	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	24.5
WP_001278906.1\|2693479_2694070_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_001291216.1\|2694109_2694982_-	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001295575.1\|2695082_2695703_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001285661.1\|2695699_2696581_-	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001700591.1\|2696718_2696763_+	trp operon leader peptide	NA	NA	NA	NA
WP_001507309.1\|2696852_2698415_+	anthranilate synthase component I	NA	NA	NA	NA
WP_000763511.1\|2698414_2700010_+	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
WP_001344826.1\|2700013_2701372_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	8.6e-37	40.7
WP_000209520.1\|2701383_2702577_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_000443067.1\|2702576_2703383_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000807651.1\|2703763_2703943_+	general stress protein	NA	NA	NA	NA
WP_104951185.1\|2704028_2704529_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001079509.1\|2704574_2705081_+	ferritin-like domain-containing protein	NA	NA	NA	NA
2705232:2705259	attL	NA	NA	NA	NA
WP_000147167.1\|2705582_2705801_+	hypothetical protein	NA	NA	NA	NA
WP_001144877.1\|2708563_2709154_-	T3SS effector guanine nucleotide exchange factor EspM1	NA	NA	NA	NA
WP_001303944.1\|2709337_2709985_+	T3SS effector E3 ubiquitin-protein ligase NleG	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
WP_001414184.1\|2710121_2710268_-	hypothetical protein	NA	NA	NA	NA
WP_104951186.1\|2710695_2710974_+	secretion protein EspO	NA	NA	NA	NA
WP_000938103.1\|2712141_2712711_-	T3SS effector caspase inhibitor NleF	NA	NA	NA	NA
WP_000950979.1\|2712776_2713688_-	type III secretion system effector kinase NleH1-2	A5LH48	Enterobacteria_phage	3.0e-134	82.2
WP_106409364.1\|2713794_2713917_-	hypothetical protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
WP_001025672.1\|2715514_2716840_+	type III secretion system effector NleA	H6WZN2	Escherichia_phage	1.9e-214	81.2
WP_001023356.1\|2717865_2718135_-\|tail	phage tail protein	A0A2R2Z347	Escherichia_phage	2.4e-44	98.9
WP_085947772.1\|2718196_2719410_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.3e-100	57.1
WP_104951187.1\|2719430_2720711_-\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	3.4e-67	98.3
WP_001228290.1\|2720862_2721462_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	4.1e-108	97.0
WP_104951188.1\|2721529_2725003_-	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	90.0
WP_158672592.1\|2725345_2725978_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-102	90.9
WP_104951190.1\|2725923_2726667_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.5e-147	97.6
WP_104951191.1\|2726677_2727376_-\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	6.8e-131	98.3
WP_000807940.1\|2727375_2727717_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
WP_104951351.1\|2727709_2730013_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	91.7
WP_158672585.1\|2730134_2730389_-	tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	8.2e-18	67.1
WP_001063099.1\|2734840_2735062_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_024216102.1\|2735106_2737044_-\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	99.8
WP_001299337.1\|2737107_2738769_-\|terminase	terminase large subunit	B6DZ98	Enterobacteria_phage	0.0e+00	98.9
WP_000958372.1\|2738765_2739329_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	3.3e-83	92.5
WP_000279786.1\|2739618_2739984_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	9.9e-65	99.2
WP_001302977.1\|2740025_2740211_+	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	3.7e-20	90.4
WP_000347013.1\|2740340_2740481_-	hypothetical protein	NA	NA	NA	NA
WP_000735655.1\|2740837_2741062_-	hypothetical protein	NA	NA	NA	NA
WP_001208682.1\|2741126_2741333_-	hypothetical protein	H6WRZ6	Salmonella_phage	7.1e-12	64.7
WP_000539792.1\|2741560_2741707_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|2741706_2742276_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992088.1\|2742546_2743080_-	lysozyme	B6DZ92	Enterobacteria_phage	5.6e-101	98.3
WP_100210028.1\|2743130_2743475_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	2.7e-56	96.5
WP_000411813.1\|2743479_2743686_-\|holin	holin	Q6H9V8	Enterobacteria_phage	1.2e-30	97.1
WP_104951193.1\|2743850_2745704_-	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	96.6
WP_077787779.1\|2747223_2747808_-	antiterminator	I6PDF8	Cronobacter_phage	3.9e-47	49.2
WP_104951194.1\|2747850_2749064_-\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	2.2e-164	96.3
WP_104951195.1\|2749115_2749226_-	antitermination protein	NA	NA	NA	NA
WP_000140002.1\|2749222_2749588_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	67.5
WP_104951196.1\|2749588_2750644_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.7e-88	47.6
WP_010917803.1\|2750645_2750924_-	hypothetical protein	I6PCV7	Cronobacter_phage	2.2e-11	48.4
WP_104951197.1\|2750993_2751251_-	hypothetical protein	NA	NA	NA	NA
WP_000961821.1\|2751471_2751684_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.3e-16	72.9
WP_001449026.1\|2751962_2752721_-	AcfC family adhesin Paa	NA	NA	NA	NA
WP_001505071.1\|2753419_2753584_-	hypothetical protein	NA	NA	NA	NA
WP_104951198.1\|2753580_2754315_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.3e-108	84.3
WP_157825328.1\|2754348_2754891_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.5e-85	98.7
WP_000020556.1\|2754802_2755843_-	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_000705622.1\|2755814_2756366_-	hypothetical protein	NA	NA	NA	NA
WP_000912298.1\|2756349_2756577_-	transcriptional regulator	NA	NA	NA	NA
WP_024216105.1\|2756653_2757061_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	5.7e-29	49.6
WP_001240336.1\|2757325_2757625_+	hypothetical protein	NA	NA	NA	NA
WP_001171903.1\|2757697_2757916_+	hypothetical protein	NA	NA	NA	NA
WP_000394552.1\|2757938_2758346_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	7.0e-11	37.8
WP_024216104.1\|2758323_2758557_-	hypothetical protein	NA	NA	NA	NA
WP_001342117.1\|2758550_2758718_-	hypothetical protein	NA	NA	NA	NA
WP_000449172.1\|2759117_2759306_+	cell division inhibitor	NA	NA	NA	NA
WP_000199480.1\|2759302_2759491_+	DUF1482 family protein	NA	NA	NA	NA
WP_000048478.1\|2759586_2762058_+	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.2
WP_000113189.1\|2762122_2762371_+	excisionase	NA	NA	NA	NA
WP_000113674.1\|2762348_2763479_+\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	3.4e-103	51.4
2763616:2763643	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2866547 : 2941797

Enterobacteria_phage(23.44%)

lysis,terminase,transposase,holin,portal,tRNA,tail,head,integrase,protease,capsid

attL 2889623:2889637|attR 2942222:2942236

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001297484.1\|2866547_2867654_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_001297479.1\|2867689_2868331_+	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000423729.1\|2868334_2869705_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
WP_001265481.1\|2869872_2870544_+	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000735412.1\|2870543_2872004_+	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_000133423.1\|2872740_2873022_-	hypothetical protein	NA	NA	NA	NA
WP_000127889.1\|2873035_2874697_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	1.5e-277	81.6
WP_000113645.1\|2874680_2875037_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	9.4e-52	81.4
WP_001145905.1\|2875326_2875767_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	2.5e-62	72.6
WP_000134113.1\|2875766_2876063_-	hypothetical protein	A0A2H4JD08	uncultured_Caudovirales_phage	4.0e-32	65.3
WP_001020668.1\|2876059_2876398_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	5.6e-30	52.7
WP_001398592.1\|2876394_2877570_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	4.8e-185	80.2
WP_072166574.1\|2877607_2878180_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.8e-60	63.0
WP_044810616.1\|2878219_2879377_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	1.6e-137	64.9
WP_000233312.1\|2879664_2879937_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_104951207.1\|2879949_2880360_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_001368652.1\|2880369_2880558_-	hypothetical protein	NA	NA	NA	NA
WP_044810615.1\|2880671_2880923_-	hypothetical protein	NA	NA	NA	NA
WP_104951208.1\|2881123_2882524_-	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.6e-115	49.6
WP_000770178.1\|2882520_2882820_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_104951209.1\|2882825_2883059_-	hypothetical protein	NA	NA	NA	NA
WP_104951210.1\|2883051_2883516_-	hypothetical protein	NA	NA	NA	NA
WP_000609225.1\|2883505_2883718_-	hypothetical protein	NA	NA	NA	NA
WP_000226782.1\|2883710_2883908_-	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_000022147.1\|2884037_2884217_+	hypothetical protein	A0A2H4JB52	uncultured_Caudovirales_phage	4.4e-10	56.9
WP_000953273.1\|2884834_2885023_-	AlpA family transcriptional regulator	A0A2H4JB58	uncultured_Caudovirales_phage	1.2e-13	66.0
WP_104951211.1\|2885386_2886616_-\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	2.3e-134	56.6
WP_001295435.1\|2886864_2887986_+	cupin domain-containing protein	NA	NA	NA	NA
WP_000359438.1\|2888131_2889361_-	peptidase T	NA	NA	NA	NA
WP_000531594.1\|2889610_2890747_+	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
2889623:2889637	attL	NA	NA	NA	NA
WP_000799400.1\|2890730_2891594_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000938120.1\|2891957_2893319_+	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	4.7e-51	29.4
WP_032361506.1\|2893381_2893657_+	hypothetical protein	NA	NA	NA	NA
WP_000950789.1\|2893736_2894717_-	NleB family type III secretion system effector arginine glycosyltransferase	Q8HAB2	Salmonella_phage	8.0e-85	48.6
WP_001023427.1\|2894894_2895164_-\|tail	phage tail protein	Q9EYE9	Enterobacteria_phage	5.4e-44	97.8
WP_001449501.1\|2896542_2897166_-	Ail/Lom family outer membrane beta-barrel protein	A0A1U8QHD6	Enterobacteria_phage	8.7e-69	60.4
WP_104951212.1\|2897234_2900714_-	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	94.6
WP_000649829.1\|2900847_2901375_+	superoxide dismutase family protein	Q9MC02	Salmonella_phage	1.8e-59	60.5
WP_158672593.1\|2901565_2902198_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	6.5e-104	92.3
WP_104951190.1\|2902143_2902887_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.5e-147	97.6
WP_104951191.1\|2902897_2903596_-\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	6.8e-131	98.3
WP_000807940.1\|2903595_2903937_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
WP_104951214.1\|2903929_2907172_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	96.6
WP_000526113.1\|2907299_2907758_-\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	8.5e-13	32.3
WP_001453698.1\|2907935_2908145_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030063.1\|2908240_2908615_-\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001275510.1\|2908620_2909337_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	1.1e-128	99.6
WP_000133391.1\|2909395_2909740_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_104951215.1\|2909736_2910183_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	4.0e-76	99.3
WP_001007905.1\|2910179_2910530_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125996.1\|2910540_2910867_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	1.6e-53	99.1
WP_001063096.1\|2913393_2913615_-	hypothetical protein	H6WZL1	Escherichia_phage	3.4e-36	100.0
WP_000173042.1\|2913659_2915597_-\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	99.5
WP_001299891.1\|2915660_2917322_-\|terminase	terminase large subunit	B6DZ98	Enterobacteria_phage	0.0e+00	99.3
WP_000958403.1\|2917318_2917882_-\|terminase	terminase small subunit	A0A0P0ZCQ9	Stx2-converting_phage	2.4e-70	84.0
WP_000829192.1\|2918173_2918539_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
WP_000095749.1\|2918580_2918808_+	DUF3950 domain-containing protein	A0A0P0ZCA1	Stx2-converting_phage	3.9e-35	100.0
WP_000736096.1\|2919176_2919401_-	hypothetical protein	NA	NA	NA	NA
WP_001082547.1\|2919397_2919892_-\|lysis	lysis protein	Q9ZXB6	Enterobacteria_phage	1.7e-83	100.0
WP_104951216.1\|2920190_2920724_-	lysozyme	B6DZ92	Enterobacteria_phage	2.8e-100	96.6
WP_000731192.1\|2920774_2921119_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	6.5e-58	98.2
WP_000411809.1\|2921123_2921330_-\|holin	holin	Q6H9V8	Enterobacteria_phage	2.4e-31	100.0
WP_104951217.1\|2921631_2923482_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.7
WP_000216623.1\|2923889_2924057_-	DUF3927 family protein	H6WZJ7	Escherichia_phage	1.1e-10	74.5
WP_001299895.1\|2924053_2924485_-	tellurite resistance protein	H6WZJ6	Escherichia_phage	2.1e-66	95.8
WP_000798624.1\|2924792_2925167_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000573777.1\|2925227_2925488_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000917767.1\|2926813_2927011_-	hypothetical protein	Q9MC00	Enterobacteria_phage	2.1e-29	100.0
WP_000762928.1\|2927237_2928059_-	antitermination protein	K7P7B9	Enterobacteria_phage	4.1e-82	61.2
WP_000904098.1\|2928055_2928430_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	3.2e-34	62.7
WP_001265175.1\|2928442_2929492_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	9.4e-108	54.0
WP_001341388.1\|2929493_2929772_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_000884071.1\|2929939_2930152_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.2e-17	67.1
WP_001278450.1\|2930340_2930445_-	hypothetical protein	NA	NA	NA	NA
WP_000627694.1\|2930560_2931145_-	DUF551 domain-containing protein	A0A0P0ZD75	Stx2-converting_phage	1.0e-34	86.1
WP_104951218.1\|2931201_2931597_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.9e-29	50.7
WP_000450874.1\|2931612_2932383_-	DUF1627 domain-containing protein	A0A088CE47	Shigella_phage	2.2e-82	67.3
WP_000788938.1\|2932408_2933149_-	ATP-binding protein	A0A088CBP4	Shigella_phage	4.6e-125	90.2
WP_000095671.1\|2933155_2934118_-	DNA-binding protein	U5P0A0	Shigella_phage	2.1e-69	51.2
WP_000693916.1\|2934140_2934566_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000711018.1\|2934549_2934873_-	transcriptional regulator	A0A0R6PH31	Moraxella_phage	6.2e-10	44.9
WP_000948452.1\|2934997_2935474_+	hypothetical protein	A0A2D1GNH0	Pseudomonas_phage	5.7e-12	53.4
WP_001443692.1\|2935792_2935948_+	DUF1391 family protein	M4QQ57	Salicola_phage	5.7e-06	48.9
WP_001171966.1\|2936107_2936326_+	hypothetical protein	NA	NA	NA	NA
WP_001358071.1\|2936329_2936494_-	hypothetical protein	NA	NA	NA	NA
WP_000449192.1\|2936894_2937083_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001090200.1\|2937079_2937271_+	DUF1482 family protein	NA	NA	NA	NA
WP_000048412.1\|2937363_2939835_+	exonuclease	K7PLW7	Enterobacteria_phage	8.5e-59	60.3
WP_000003742.1\|2939896_2940166_+	excisionase	NA	NA	NA	NA
WP_000074973.1\|2940134_2941253_+\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	2.0e-84	44.4
WP_001113310.1\|2941329_2941797_-	DUF2335 domain-containing protein	A0A1B0YZW3	Pseudomonas_phage	4.4e-09	35.0
2942222:2942236	attR	NA	NA	NA	NA

DBSCAN-SWA_8

3030113 : 3121141

101

Enterobacteria_phage(35.06%)

terminase,transposase,tail,head,integrase,protease,holin,capsid

attL 3067673:3067687|attR 3122120:3122134

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085950013.1\|3030113_3031275_+\|transposase	IS3-like element IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.4e-51	40.6
WP_000409883.1\|3031316_3032675_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.9e-20	33.2
WP_000287434.1\|3033261_3035685_+	poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA	NA	NA	NA	NA
WP_024215820.1\|3035693_3037712_+	poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB	NA	NA	NA	NA
WP_000610451.1\|3037704_3039030_+	poly-beta-1,6 N-acetyl-D-glucosamine synthase	NA	NA	NA	NA
WP_089645745.1\|3039031_3039445_+	poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD	NA	NA	NA	NA
WP_001295604.1\|3039494_3040418_-	phosphate starvation-inducible protein PhoH	R4II13	Cronobacter_phage	4.1e-91	76.2
WP_001199458.1\|3040901_3042173_-	deferrochelatase/peroxidase EfeB	NA	NA	NA	NA
WP_089645744.1\|3042178_3043306_-	iron uptake system protein EfeO	NA	NA	NA	NA
WP_000497941.1\|3043363_3044194_-	FTR1 family protein	NA	NA	NA	NA
WP_001018496.1\|3044735_3046244_-	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000979516.1\|3046402_3046612_-	hypothetical protein	NA	NA	NA	NA
WP_104951221.1\|3046666_3050629_+	trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_001331086.1\|3050668_3051307_-	HTH-type transcriptional regulator RutR	NA	NA	NA	NA
WP_158672594.1\|3051594_3052686_+	pyrimidine utilization protein A	NA	NA	NA	NA
WP_001307708.1\|3052685_3053378_+	peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB	NA	NA	NA	NA
WP_001126777.1\|3053389_3053776_+	pyrimidine utilization protein C	NA	NA	NA	NA
WP_001345413.1\|3053783_3054584_+	pyrimidine utilization protein D	NA	NA	NA	NA
WP_104951223.1\|3054593_3055184_+	malonic semialdehyde reductase	NA	NA	NA	NA
WP_001028095.1\|3055194_3055689_+	pyrimidine utilization flavin reductase protein F	Q9KX93	Enterobacteria_phage	5.0e-51	97.9
WP_001240628.1\|3055709_3057038_+	pyrimidine utilization transport protein G	Q9KX94	Enterobacteria_phage	1.0e-231	98.4
WP_001273658.1\|3057120_3057294_-	general stress protein	Q9KX95	Enterobacteria_phage	4.9e-06	96.3
WP_104951224.1\|3057666_3058263_+	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_001143120.1\|3058283_3058511_+	hypothetical protein	NA	NA	NA	NA
WP_001044263.1\|3058548_3059790_-	bifunctional glucose-1-phosphatase/inositol phosphatase	NA	NA	NA	NA
WP_000097604.1\|3060078_3061338_-	YccE family protein	NA	NA	NA	NA
WP_000420629.1\|3061597_3062518_+	curved DNA-binding protein	A0A1V0SIM1	Klosneuvirus	3.2e-11	43.0
WP_000024561.1\|3062517_3062823_+	chaperone modulator CbpM	NA	NA	NA	NA
WP_104951225.1\|3062915_3063515_-	molecular chaperone TorD	NA	NA	NA	NA
WP_001062102.1\|3063511_3066058_-	trimethylamine-N-oxide reductase TorA	A0A077SK27	Escherichia_phage	5.9e-71	29.2
WP_001230242.1\|3066057_3067230_-	pentaheme c-type cytochrome TorC	NA	NA	NA	NA
WP_001120112.1\|3067359_3068052_+	two-component system response regulator TorR	W8CYM9	Bacillus_phage	4.5e-18	28.0
3067673:3067687	attL	NA	NA	NA	NA
WP_001264955.1\|3068024_3069053_-	TMAO reductase system periplasmic protein TorT	NA	NA	NA	NA
WP_001023417.1\|3070638_3070908_-\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	2.4e-44	98.9
WP_104951226.1\|3070909_3072223_-\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	3.3e-78	98.9
WP_089645828.1\|3072287_3072887_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	3.0e-111	99.5
WP_122995614.1\|3076669_3077302_-\|tail	tail assembly protein	A0A0P0ZDX8	Stx2-converting_phage	1.2e-105	99.0
WP_000967281.1\|3077247_3077985_-\|tail	phage tail protein	A0A0P0ZDT1	Stx2-converting_phage	6.1e-146	97.1
WP_001428824.1\|3078039_3078963_-	phage antirepressor Ant	A0A0N7KZK0	Stx2-converting_phage	1.3e-177	100.0
WP_001154345.1\|3079033_3079207_-	Arc family DNA-binding protein	A0A0P0ZC65	Stx2-converting_phage	3.4e-23	100.0
WP_001302649.1\|3079314_3079635_+	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.0e-49	100.0
WP_064482889.1\|3079651_3080350_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	1.5e-130	97.4
WP_032272839.1\|3080349_3080691_-\|tail	phage tail protein	H6WZM2	Escherichia_phage	6.2e-61	96.5
WP_062893485.1\|3080683_3083926_-\|tail	phage tail tape measure protein	A0A0P0ZE78	Stx2-converting_phage	0.0e+00	98.3
WP_122987477.1\|3083976_3084186_-	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	4.4e-33	98.6
WP_001030042.1\|3084281_3084656_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	6.6e-64	98.4
WP_062893616.1\|3084661_3085378_-\|tail	phage tail protein	A0A0P0ZD29	Stx2-converting_phage	1.5e-128	99.2
WP_000133388.1\|3085444_3085789_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573391.1\|3085785_3086232_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007905.1\|3086228_3086579_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125988.1\|3086588_3086915_-\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_001063096.1\|3089603_3089825_-	hypothetical protein	H6WZL1	Escherichia_phage	3.4e-36	100.0
WP_069722247.1\|3089869_3091807_-\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	99.8
WP_069722248.1\|3091870_3093532_-\|terminase	terminase large subunit	H6WZK9	Escherichia_phage	0.0e+00	99.5
WP_000958398.1\|3093528_3094092_-\|terminase	terminase small subunit	B6DZ97	Enterobacteria_phage	7.3e-83	94.1
WP_104951227.1\|3094380_3094746_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	4.2e-63	98.3
WP_000095732.1\|3094787_3094988_+	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	3.7e-29	95.5
WP_000828070.1\|3095119_3095446_-	TonB family protein	H6WZK5	Escherichia_phage	6.3e-55	98.1
WP_012816791.1\|3095846_3096032_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_001280923.1\|3096254_3096386_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	3.8e-11	93.0
WP_000661708.1\|3096480_3097176_-	phage antirepressor protein	Q5MBW0	Stx1-converting_phage	3.6e-124	98.7
WP_025380493.1\|3097449_3097983_-	lysozyme	Q6H9V6	Enterobacteria_phage	1.3e-100	96.0
WP_024216148.1\|3098033_3098378_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	2.1e-56	97.4
WP_000411813.1\|3098382_3098589_-\|holin	holin	Q6H9V8	Enterobacteria_phage	1.2e-30	97.1
WP_024216036.1\|3098881_3100732_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.7
WP_024216035.1\|3101210_3101639_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	6.4e-63	97.1
WP_000512807.1\|3102280_3102769_-	late gene antiterminator protein	Q5TJL7	Enterobacteria_phage	7.0e-90	100.0
WP_001028858.1\|3102759_3103431_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	2.4e-133	100.0
WP_024216034.1\|3103427_3104030_-	protein ninG	A0A1U9AJF8	Stx1_converting_phage	3.9e-90	94.6
WP_001108084.1\|3104004_3104571_-	endonuclease	A0A1U9AJK5	Stx1_converting_phage	6.6e-108	99.5
WP_069720699.1\|3105146_3106919_+	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	0.0e+00	99.3
WP_001254221.1\|3107422_3107605_-	NinE family protein	Q8H9Z6	Enterobacteria_phage	1.3e-28	98.3
WP_000153288.1\|3107601_3108129_-	phage N-6-adenine-methyltransferase	Q9ZWX6	Enterobacteria_phage	7.3e-101	100.0
WP_024216032.1\|3108125_3108572_-	recombination protein NinB	Q8VNP6	Enterobacteria_phage	1.2e-80	98.6
WP_001281772.1\|3108528_3108765_-	restriction alleviation protein, Lar family	Q8HA09	Enterobacteria_phage	1.2e-39	100.0
WP_000103678.1\|3108775_3108991_-	hypothetical protein	A0A0N7KZ98	Stx2-converting_phage	7.7e-33	100.0
WP_001000130.1\|3109123_3109402_-	hypothetical protein	Q9EYB9	Enterobacteria_phage	4.4e-49	100.0
WP_000145908.1\|3109472_3109763_-	protein ren	A0A0N6WES4	Escherichia_phage	5.7e-47	100.0
WP_069720698.1\|3109759_3110461_-	Replication protein P	Q6H9X6	Enterobacteria_phage	4.9e-129	99.1
WP_000185454.1\|3110457_3111396_-	replication protein	A0A1I9LJP3	Stx_converting_phage	1.3e-172	100.0
WP_000442609.1\|3111428_3111725_-	hypothetical protein	G9L678	Escherichia_phage	2.2e-46	94.9
WP_000276885.1\|3111834_3112020_-	hypothetical protein	K7PHK4	Enterobacteria_phage	1.2e-26	100.0
WP_001095982.1\|3112100_3112751_+	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	4.9e-123	100.0
WP_000256573.1\|3113065_3113371_+	hypothetical protein	K7PJM7	Enterobacteria_phage	7.0e-48	99.0
WP_000930321.1\|3113373_3113712_+	hypothetical protein	K7PJW2	Enterobacteria_phage	5.8e-59	99.1
WP_000167595.1\|3113845_3114316_+	hypothetical protein	A0A1I9LJN4	Stx_converting_phage	3.7e-88	100.0
WP_072795882.1\|3114465_3114834_+	DUF2528 family protein	A0A0N7C1W2	Escherichia_phage	2.9e-64	98.4
WP_001198861.1\|3114906_3115071_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q776Q5	Enterobacteria_phage	1.1e-26	100.0
WP_000372937.1\|3115039_3115183_+	host cell division inhibitory peptide Kil	A0A0N7C2U2	Escherichia_phage	1.2e-18	100.0
WP_000995416.1\|3115257_3115554_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	4.7e-49	99.0
WP_001373974.1\|3115559_3116345_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	1.4e-148	99.6
WP_000186759.1\|3116341_3117022_+	YqaJ viral recombinase family protein	H6WZG6	Escherichia_phage	1.8e-131	98.7
WP_000682299.1\|3117018_3117201_+	DUF1317 domain-containing protein	Q6H9Z1	Enterobacteria_phage	3.7e-28	98.3
WP_000548531.1\|3117173_3117365_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	7.3e-27	100.0
WP_001386642.1\|3117375_3117657_+	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	5.5e-47	98.9
WP_104951228.1\|3117755_3117977_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.4e-34	98.6
WP_069720661.1\|3117973_3118744_+	ead/Ea22-like family protein	H6WZG2	Escherichia_phage	4.7e-141	98.8
WP_044805131.1\|3118745_3119483_+	DUF551 domain-containing protein	G9L6B4	Escherichia_phage	4.2e-54	51.0
WP_001277767.1\|3119579_3119759_+	Eag protein	K7PL40	Enterobacteria_phage	2.5e-29	100.0
WP_001303849.1\|3119871_3120090_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_069720662.1\|3120067_3121141_+\|integrase	tyrosine-type recombinase/integrase	K7PHK0	Enterobacteria_phage	1.8e-194	96.1
3122120:3122134	attR	NA	NA	NA	NA

DBSCAN-SWA_9

3140250 : 3193594

Enterobacteria_phage(39.53%)

terminase,transposase,holin,portal,tail,head,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000003671.1\|3140250_3140838_-\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA
WP_089645770.1\|3140834_3141542_-	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_089645771.1\|3141560_3143354_-	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_032267472.1\|3143350_3144469_-	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_059225203.1\|3145308_3145620_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_024215812.1\|3145735_3146944_+	hypothetical protein	H6WZN3	Escherichia_phage	2.1e-204	89.3
WP_024215811.1\|3147503_3148064_-	T3SS effector NleG family protein	H6WZN1	Escherichia_phage	1.2e-64	67.5
WP_001023428.1\|3148178_3148448_-\|tail	phage tail protein	Q9EYE9	Enterobacteria_phage	2.4e-44	98.9
WP_024215810.1\|3148449_3149763_-\|tail	tail fiber protein	A0A0P0ZCC1	Stx2-converting_phage	6.7e-79	96.8
WP_104951230.1\|3149823_3153237_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	97.1
WP_000090891.1\|3153297_3153930_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	2.2e-96	99.5
WP_047378280.1\|3153866_3154610_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.8e-146	96.0
WP_001152639.1\|3154615_3155314_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.3e-134	100.0
WP_000847379.1\|3155313_3155643_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
WP_104951231.1\|3155639_3158201_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	85.3
WP_000533431.1\|3158181_3158595_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.0e-41	82.8
WP_000479086.1\|3158621_3159053_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	4.8e-42	68.1
WP_001143013.1\|3159066_3159819_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.7e-127	93.6
WP_000683071.1\|3159826_3160222_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	4.2e-61	87.0
WP_024216041.1\|3160218_3160794_-\|tail	tail protein	A0A2R9YJK4	Escherichia_phage	4.9e-50	58.3
WP_097344466.1\|3160986_3162199_+\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	1.0e-166	97.6
WP_000201528.1\|3162467_3162842_-	hypothetical protein	NA	NA	NA	NA
WP_000522630.1\|3162893_3163922_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.3e-114	61.3
WP_000256818.1\|3163979_3164327_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.0e-22	58.1
WP_104951232.1\|3165857_3167450_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	4.2e-184	61.3
WP_000258991.1\|3167446_3167653_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	4.2e-12	60.0
WP_024216039.1\|3167636_3169565_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.0e-261	66.2
WP_000235436.1\|3169536_3170046_-\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_001431375.1\|3170440_3170665_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	5.9e-20	92.5
WP_001303878.1\|3170746_3171061_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_012816791.1\|3171587_3171773_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000675931.1\|3171994_3172108_-	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_001003118.1\|3172328_3172862_-	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.1e-99	94.4
WP_000138558.1\|3173021_3173294_+	hypothetical protein	NA	NA	NA	NA
WP_000411814.1\|3173549_3173756_-\|holin	holin	Q6H9V8	Enterobacteria_phage	5.3e-31	98.5
WP_104951233.1\|3174203_3176054_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.1
WP_000261909.1\|3176821_3177535_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001303877.1\|3177629_3177869_-	hypothetical protein	Q9MC00	Enterobacteria_phage	7.7e-18	98.0
WP_000265265.1\|3178155_3178974_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000090265.1\|3179125_3179497_-	antitermination protein	Q777W5	Enterobacteria_phage	1.0e-53	84.0
WP_001217436.1\|3179486_3179858_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_024215596.1\|3179870_3180920_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	2.5e-108	54.6
WP_001341388.1\|3180921_3181200_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001013642.1\|3181367_3181580_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.5e-25	95.4
WP_000955173.1\|3181624_3181762_+	hypothetical protein	Q7Y2Q9	Escherichia_phage	5.4e-08	96.6
WP_000160655.1\|3182127_3182901_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_001151233.1\|3183252_3183666_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	9.8e-61	89.1
WP_024215598.1\|3183681_3184452_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.0e-79	64.1
WP_000788751.1\|3184473_3185220_-	ATP-binding protein	A0A088CBP4	Shigella_phage	6.2e-114	84.2
WP_001205820.1\|3185226_3186342_-	hypothetical protein	V5URT9	Shigella_phage	2.2e-131	68.4
WP_000273724.1\|3186420_3186876_+	hypothetical protein	NA	NA	NA	NA
WP_000693855.1\|3187082_3187508_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000887453.1\|3187491_3187764_-	hypothetical protein	A0A0U2S629	Escherichia_phage	1.1e-12	45.8
WP_000986592.1\|3187872_3188274_+	helix-turn-helix domain-containing protein	A0A1B5FPF4	Escherichia_phage	7.4e-13	54.5
WP_000536233.1\|3188301_3188493_+	hypothetical protein	NA	NA	NA	NA
WP_001303876.1\|3188492_3188780_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000379575.1\|3189056_3189212_+	DUF1391 family protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_000394511.1\|3189353_3189743_+	hypothetical protein	NA	NA	NA	NA
WP_024215602.1\|3189929_3190115_-	hypothetical protein	NA	NA	NA	NA
WP_000413705.1\|3190688_3190877_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001098307.1\|3190873_3191065_+	DUF1482 family protein	NA	NA	NA	NA
WP_104951234.1\|3191158_3193594_+	exonuclease	A0A192Y6E0	Salmonella_phage	8.4e-59	58.2

DBSCAN-SWA_10

3380946 : 3470818

110

Enterobacteria_phage(49.33%)

terminase,transposase,holin,portal,tail,head,integrase,protease,lysis,capsid

attL 3395659:3395693|attR 3472252:3472286

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067858.1\|3380946_3381651_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000569080.1\|3381726_3382449_+	glutamine ABC transporter ATP-binding protein GlnQ	G9BWD6	Planktothrix_phage	2.5e-35	41.8
WP_089645723.1\|3382565_3384791_+	mechanosensitive channel protein	NA	NA	NA	NA
WP_001295299.1\|3384787_3385714_-	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	NA	NA	NA	NA
WP_001350031.1\|3385989_3386250_+	DUF1471 domain-containing protein	A0A1B2ICL8	Erwinia_phage	5.7e-06	53.1
WP_000430057.1\|3386514_3388797_+	catecholate siderophore receptor Fiu	NA	NA	NA	NA
WP_000990177.1\|3388838_3389516_+	PKHD-type hydroxylase YbiX	Q5GQB0	Synechococcus_phage	1.2e-18	30.1
WP_000146343.1\|3389589_3389856_+	C4-type zinc finger protein YbiI	E5G6L7	Salmonella_phage	6.9e-07	45.6
WP_000849301.1\|3390120_3390381_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_000443530.1\|3390609_3391695_-	malate/lactate/ureidoglycolate dehydrogenase	NA	NA	NA	NA
WP_000386551.1\|3391835_3392798_-	DNA-binding protein YbiB	NA	NA	NA	NA
WP_001340191.1\|3392825_3394976_-	ATP-dependent DNA helicase DinG	A0A127AW80	Bacillus_phage	3.7e-42	26.1
WP_001145128.1\|3395095_3395578_+	N-glycosidase YbiA	A0A0H3TLU0	Faustovirus	1.5e-36	52.7
3395659:3395693	attL	NA	NA	NA	NA
WP_104951248.1\|3395809_3397174_-	ATP-dependent RNA helicase RhlE	A0A1V0SBR7	Catovirus	2.3e-53	32.1
WP_001296991.1\|3397402_3398074_+	DNA-binding transcriptional regulator CecR	NA	NA	NA	NA
WP_001296990.1\|3398076_3399072_+	secretion protein HlyD	NA	NA	NA	NA
WP_000996099.1\|3399064_3400801_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.3e-18	29.8
WP_000070131.1\|3400793_3401927_+	ABC transporter permease	NA	NA	NA	NA
WP_000469031.1\|3401937_3403044_+	ABC transporter permease	NA	NA	NA	NA
WP_000871982.1\|3403005_3403416_-	hypothetical protein	NA	NA	NA	NA
WP_001113351.1\|3403548_3404310_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000650337.1\|3404306_3405548_+	cardiolipin synthase ClsB	NA	NA	NA	NA
WP_000045448.1\|3405547_3406504_+	UPF0104 family protein	NA	NA	NA	NA
WP_000446932.1\|3406539_3407253_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_000373624.1\|3407457_3408162_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_000852287.1\|3408298_3408751_-	molybdopterin synthase catalytic subunit MoaE	NA	NA	NA	NA
WP_104951249.1\|3408752_3408998_-	molybdopterin synthase sulfur carrier subunit	NA	NA	NA	NA
WP_000080885.1\|3408990_3409476_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_000084632.1\|3409478_3409991_-	molybdenum cofactor biosynthesis protein B	NA	NA	NA	NA
WP_001295301.1\|3410012_3411002_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_001295302.1\|3411398_3412307_+	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	1.4e-27	31.1
WP_000042533.1\|3412498_3414520_-	excinuclease ABC subunit B	NA	NA	NA	NA
WP_000044868.1\|3415098_3415776_-	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_000246805.1\|3415768_3416524_-	malonyl-ACP O-methyltransferase BioC	NA	NA	NA	NA
WP_024215917.1\|3416510_3417665_-	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_000951213.1\|3417661_3418702_-	biotin synthase BioB	NA	NA	NA	NA
WP_001389241.1\|3418788_3420078_+	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	3.8e-18	28.9
WP_000767389.1\|3420136_3420613_+	kinase inhibitor	NA	NA	NA	NA
WP_001121571.1\|3421116_3421770_+	type III secretion system effector ADP-ribosyltransferase EspJ	NA	NA	NA	NA
WP_000354291.1\|3421782_3422004_-	hypothetical protein	NA	NA	NA	NA
WP_001002868.1\|3422087_3422468_-	hypothetical protein	NA	NA	NA	NA
WP_104951250.1\|3423686_3424058_+\|integrase	integrase	K7PH54	Enterobacteria_phage	1.1e-58	94.3
WP_001381875.1\|3424161_3425016_-	type III secretion system effector Cif	A5LH49	Enterobacteria_phage	1.1e-149	98.9
WP_000950982.1\|3425232_3426114_-	hypothetical protein	A5LH48	Enterobacteria_phage	3.9e-147	90.4
WP_104951251.1\|3426219_3426489_-\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	1.6e-43	97.8
WP_104951252.1\|3426490_3427813_-\|tail	phage tail protein	Q687E6	Enterobacteria_phage	2.4e-76	98.9
WP_001358466.1\|3427877_3428477_-	Ail/Lom family outer membrane beta-barrel protein	A5LH44	Enterobacteria_phage	7.0e-108	97.0
WP_104951253.1\|3428547_3431961_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	97.1
WP_000090891.1\|3432021_3432654_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	2.2e-96	99.5
WP_047378280.1\|3432590_3433334_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.8e-146	96.0
WP_001152639.1\|3433339_3434038_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.3e-134	100.0
WP_000847379.1\|3434037_3434367_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
WP_104951254.1\|3434363_3436925_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	90.5
WP_000459457.1\|3436917_3437352_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479193.1\|3437333_3437756_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.2e-60	85.7
WP_001317730.1\|3437771_3438512_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	5.2e-129	97.2
WP_000683129.1\|3438519_3438915_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	8.5e-70	98.5
WP_000975081.1\|3438911_3439490_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000785282.1\|3439501_3439855_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	6.4e-61	97.4
WP_000158875.1\|3439866_3440262_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	1.1e-58	95.5
WP_000063254.1\|3440303_3441329_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	2.8e-189	98.2
WP_104951255.1\|3441384_3441717_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	4.2e-54	97.3
WP_104951256.1\|3441726_3443046_-	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	2.4e-233	98.6
WP_089645795.1\|3443026_3444628_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	3.2e-309	98.7
WP_000198149.1\|3444624_3444831_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_053890143.1\|3444827_3446753_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.4
WP_000453611.1\|3446727_3447273_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.3e-94	98.3
WP_001307652.1\|3447661_3447856_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
WP_000881326.1\|3448043_3448661_-	hypothetical protein	A0A1R3Y613	Salmonella_virus	6.5e-93	85.9
WP_000092318.1\|3448810_3449248_-\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	2.0e-72	100.0
WP_000075132.1\|3449244_3449742_-	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_000411802.1\|3449741_3449948_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000023271.1\|3450395_3452246_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	95.9
WP_114145326.1\|3452547_3452703_-	DUF3927 family protein	NA	NA	NA	NA
WP_001097238.1\|3453715_3454405_-	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.5e-58	48.1
WP_032160865.1\|3454419_3454542_-	YlcG family protein	NA	NA	NA	NA
WP_000750155.1\|3454881_3455841_+	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_000994516.1\|3456052_3456241_-	protein ninH	A5VW84	Enterobacteria_phage	5.5e-27	100.0
WP_001008193.1\|3456237_3456600_-	RusA family crossover junction endodeoxyribonuclease	A5VW85	Enterobacteria_phage	2.7e-62	99.2
WP_001286917.1\|3456879_3457092_-	hypothetical protein	K7PK10	Enterobacteria_phage	1.6e-35	100.0
WP_000950962.1\|3457084_3457261_-	protein ninF	A0A220NRM2	Escherichia_phage	1.9e-26	100.0
WP_000386661.1\|3457260_3457620_-	DUF2591 family protein	G8EYI2	Enterobacteria_phage	2.7e-62	95.0
WP_001254220.1\|3457622_3457799_-	NinE family protein	K7PHE6	Enterobacteria_phage	2.7e-28	100.0
WP_000153280.1\|3457795_3458323_-	phage N-6-adenine-methyltransferase	A0A1I9LJP9	Stx_converting_phage	9.5e-101	100.0
WP_000736904.1\|3458319_3458760_-	recombination protein NinB	A5VW91	Enterobacteria_phage	7.0e-81	100.0
WP_000145931.1\|3458833_3459124_-	protein ren	A0A1I9LJP5	Stx_converting_phage	9.6e-47	100.0
WP_000788869.1\|3459120_3459822_-	Replication protein P	A0A0P0ZD31	Stx2-converting_phage	1.3e-129	99.6
WP_000185522.1\|3459818_3460718_-	replication protein	A0A0K2FJ31	Enterobacteria_phage	2.1e-172	99.3
WP_001177650.1\|3460752_3461031_-	transcriptional regulator	K7P7A2	Enterobacteria_phage	1.6e-43	100.0
WP_000276886.1\|3461139_3461325_-	hypothetical protein	A5VW97	Enterobacteria_phage	1.6e-26	100.0
WP_001095981.1\|3461405_3462056_+	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	4.1e-122	98.6
WP_001358311.1\|3462368_3462641_+	hypothetical protein	K7PH69	Enterobacterial_phage	4.0e-26	96.7
WP_001066169.1\|3462657_3463239_-	superinfection exclusion protein B	Q9EYA9	Enterobacteria_phage	4.0e-100	100.0
WP_000065374.1\|3463499_3463868_+	DUF2528 family protein	M1FPD2	Enterobacteria_phage	2.0e-65	100.0
WP_001198861.1\|3463940_3464105_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q776Q5	Enterobacteria_phage	1.1e-26	100.0
WP_000372937.1\|3464073_3464217_+	host cell division inhibitory peptide Kil	A0A0N7C2U2	Escherichia_phage	1.2e-18	100.0
WP_000995416.1\|3464291_3464588_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	4.7e-49	99.0
WP_001373974.1\|3464593_3465379_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	1.4e-148	99.6
WP_000186759.1\|3465375_3466056_+	YqaJ viral recombinase family protein	H6WZG6	Escherichia_phage	1.8e-131	98.7
WP_000682299.1\|3466052_3466235_+	DUF1317 domain-containing protein	Q6H9Z1	Enterobacteria_phage	3.7e-28	98.3
WP_000548531.1\|3466207_3466399_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	7.3e-27	100.0
WP_001395510.1\|3466409_3466691_+	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	2.5e-47	100.0
WP_000763369.1\|3466789_3467011_+	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	5.5e-34	95.9
WP_000111054.1\|3467007_3467259_+	ead/Ea22-like family protein	A0A0K2FJF6	Enterobacteria_phage	5.8e-32	92.3
WP_000748282.1\|3467557_3468172_+	hypothetical protein	NA	NA	NA	NA
WP_104951258.1\|3468465_3468804_+	hypothetical protein	A0A0F6TJR3	Escherichia_coli_O157_typing_phage	7.1e-49	85.7
WP_000762731.1\|3468832_3469261_+	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_000545741.1\|3469344_3469512_+	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	4.9e-27	98.2
WP_001303849.1\|3469551_3469770_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000533646.1\|3469747_3470818_+\|integrase	tyrosine-type recombinase/integrase	Q9MCR4	Enterobacteria_phage	1.9e-201	99.7
3472252:3472286	attR	NA	NA	NA	NA

DBSCAN-SWA_11

3702042 : 3710232

Shigella_phage(72.73%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101973092.1\|3702042_3703255_+\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	1.0e-166	97.6
WP_001250269.1\|3704164_3704344_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_000515829.1\|3704519_3705077_-	protein YmfL	S5FXP0	Shigella_phage	1.1e-96	96.2
WP_000649477.1\|3705120_3705321_-	transcriptional regulator	U5P445	Shigella_phage	7.9e-32	100.0
WP_000848748.1\|3705411_3706086_+	LexA family transcriptional repressor	U5P0T5	Shigella_phage	1.2e-132	100.0
WP_000559922.1\|3706300_3706816_-	hypothetical protein	NA	NA	NA	NA
WP_000135682.1\|3707286_3707649_+	hypothetical protein	U5P4J6	Shigella_phage	3.3e-60	100.0
WP_000081287.1\|3707714_3708539_+	DUF2303 family protein	U5P439	Shigella_phage	6.0e-150	100.0
WP_000008165.1\|3708666_3709203_+	5'-deoxynucleotidase	U5P0T3	Shigella_phage	4.8e-100	98.3
WP_001242707.1\|3709193_3709556_+	phage protein	K7PH61	Enterobacteria_phage	4.4e-65	98.3
WP_000206810.1\|3709555_3709861_+	hypothetical protein	U5P0J0	Shigella_phage	2.2e-49	97.0
WP_000433946.1\|3709860_3710232_+	helix-turn-helix domain-containing protein	S5FM74	Shigella_phage	2.5e-47	82.8

DBSCAN-SWA_12

3988920 : 4042592

Enterobacteria_phage(20.0%)

plate,integrase,capsid

attL 3988815:3988834|attR 4001014:4001033

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3988815:3988834	attL	NA	NA	NA	NA
WP_059250309.1\|3988920_3990255_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_104951292.1\|3990335_3991049_-	hypothetical protein	A0A291LAA9	Escherichia_phage	1.3e-47	47.0
WP_104951293.1\|3991082_3992918_-	hypothetical protein	I7HJD8	Enterobacteria_phage	1.9e-31	29.8
WP_000452041.1\|3992932_3993136_-	hypothetical protein	NA	NA	NA	NA
WP_059250304.1\|3993221_3994250_-\|capsid	phage capsid protein	NA	NA	NA	NA
WP_059250302.1\|3994268_3994631_-	hypothetical protein	NA	NA	NA	NA
WP_032314825.1\|3994627_3994840_-	hypothetical protein	NA	NA	NA	NA
WP_059250300.1\|3995172_3995508_-	hypothetical protein	NA	NA	NA	NA
WP_001403519.1\|3995509_3995920_-	hypothetical protein	NA	NA	NA	NA
WP_000617150.1\|3996049_3996328_-	hypothetical protein	NA	NA	NA	NA
WP_072249530.1\|3996339_3996897_-	transcriptional regulator	NA	NA	NA	NA
WP_040080436.1\|3997140_3997329_-	hypothetical protein	NA	NA	NA	NA
WP_021558589.1\|3999280_3999820_+	recombinase family protein	Q2A092	Sodalis_phage	2.4e-27	42.5
WP_024215450.1\|4001204_4002458_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	6.4e-95	47.0
4001014:4001033	attR	NA	NA	NA	NA
WP_001285288.1\|4002469_4003573_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_104951294.1\|4003860_4004916_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	2.6e-118	60.9
WP_000174677.1\|4004954_4005356_-	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_000189539.1\|4005413_4006658_-	esterase FrsA	NA	NA	NA	NA
WP_001291990.1\|4006749_4007208_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_104951295.1\|4007468_4008926_+	cytosol nonspecific dipeptidase	NA	NA	NA	NA
WP_000602114.1\|4008982_4009597_-	peptide chain release factor H	NA	NA	NA	NA
WP_001059855.1\|4010976_4011429_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001226164.1\|4011425_4012481_-	DNA polymerase IV	NA	NA	NA	NA
WP_089645775.1\|4012551_4013322_-	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
WP_001358298.1\|4013281_4015021_+	flagellar type III secretion system protein FlhA	NA	NA	NA	NA
WP_024216089.1\|4015125_4015404_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_001030486.1\|4015396_4015753_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_000543897.1\|4015809_4016583_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.6e-19	37.7
WP_024216090.1\|4016768_4017029_+	type II toxin-antitoxin system antitoxin DinJ	NA	NA	NA	NA
WP_000615976.1\|4017031_4017310_+	type II toxin-antitoxin system mRNA interferase toxin YafQ	NA	NA	NA	NA
WP_001225679.1\|4017465_4018206_+	murein L,D-transpeptidase	NA	NA	NA	NA
WP_000333380.1\|4018176_4018944_-	class II glutamine amidotransferase	NA	NA	NA	NA
WP_000284050.1\|4019149_4019728_-	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
WP_104951296.1\|4019967_4022412_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_000532698.1\|4022454_4022928_-	C-lysozyme inhibitor	NA	NA	NA	NA
WP_001118037.1\|4023081_4023849_+	2-oxoglutaramate amidase	NA	NA	NA	NA
WP_089645811.1\|4025469_4025919_-	hypothetical protein	NA	NA	NA	NA
WP_021499015.1\|4025930_4030184_-	RHS repeat protein	A0A2H4JHK7	uncultured_Caudovirales_phage	3.2e-21	44.2
WP_024216093.1\|4030259_4032401_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.1e-25	25.0
WP_001142958.1\|4032610_4033129_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000037389.1\|4033826_4034327_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_000123970.1\|4034361_4034586_+	hypothetical protein	NA	NA	NA	NA
WP_104951297.1\|4034636_4036112_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_089645755.1\|4036118_4036532_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_104951298.1\|4036535_4038386_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_000348793.1\|4038349_4039432_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_001113725.1\|4039456_4040737_+	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_001080149.1\|4040733_4041258_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_000246421.1\|4041260_4042592_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_13

4417367 : 4427875

Enterobacteria_phage(80.0%)

integrase

attL 4407239:4407253|attR 4435475:4435489

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4407239:4407253	attL	NA	NA	NA	NA
WP_001022619.1\|4417367_4418837_+	serine/threonine protein kinase	A0A2K9L5Y0	Tupanvirus	1.4e-11	26.5
WP_001218329.1\|4419037_4420303_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.1e-81	43.1
WP_122984246.1\|4420518_4420713_-\|integrase	integrase	Q38404	Enterobacteria_phage	3.8e-23	98.0
WP_104951314.1\|4421059_4423393_-	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	99.0
WP_104951315.1\|4423407_4423728_-	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_000459294.1\|4423863_4424319_-	hypothetical protein	Q7M298	Enterobacteria_phage	1.6e-64	99.1
WP_104951316.1\|4424311_4424599_-	Derepression protein	Q7M2A0	Enterobacteria_phage	1.9e-47	96.8
WP_000980222.1\|4424591_4425182_-	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	4.1e-60	90.3
WP_001149160.1\|4425178_4425445_-	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_097519058.1\|4425997_4426732_+	glycoprotein 3	Q7M2A2	Enterobacteria_phage	1.8e-129	98.0
WP_000638628.1\|4426728_4427229_+	transactivation protein	NA	NA	NA	NA
WP_000446131.1\|4427302_4427875_+	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	6.5e-95	96.8
4435475:4435489	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP025318

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection