CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014041	Vibrio alginolyticus strain FDAARGOS_110 chromosome 2, complete sequence	0 crisprs	csa3,RT,cas3,WYL,DEDDh	0	0	0	0
NZ_CP014040	Vibrio alginolyticus strain FDAARGOS_110 chromosome 1, complete sequence	1 crisprs	DinG,csa3,cas3,csx1,DEDDh,PrimPol,WYL,RT	2	1	2	0

1. NZ_CP014040

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014040_1

• CRISPR_ID: NZ_CP014040_1
• CRISPR_location: 2658481-2658727
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP014040_1

Consensus_repeat	Method
TAATGCCTCCTTAGCTCAGTAGGTAGAGCAACGGACTGATAATCCG	PILER-CR

spacers of NZ_CP014040_1

>1.1|2658527|37|NZ_CP014040|PILER-CR
TAGGTCACCAGTTCGATTCCGGTAGTCGGCACCATTC
>1.2|2658610|75|NZ_CP014040|PILER-CR
CGTGTCGGTGGTTCGATTCCGCCTCGAGGCACCATATCTGGTGCACTTGCTTCATAAGCAAGACACAAAAAAGAA

CRISPR arrays and Neighbor proteins around NZ_CP014040_1

CRISPR arrays

The CRISPR arrays of NZ_CP014040_1

>merge|NZ_CP014040|1|2658481-2658727|PILER-CR
TGCCGACTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGGTCACCAGTTCGATTCCGGTAGTCGGCACCATTCTTTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTGTCGGTGGTTCGATTCCGCCTCGAGGCACCATATCTGGTGCACTTGCTTCATAAGCAAGACACAAAAAAGAATAATTCCTCCTTAGCTCAGTTGGTAGAGCGACGGACTGTTAATCCG

>NZ_CP014040|1|1|2658481-2658727|PILER-CR
TGCCGACTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAG	GTCACCAGTTCGATTCCGGTAGTCGGCACCATTCTTT
TGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGT	GTCGGTGGTTCGATTCCGCCTCGAGGCACCATATCTGGTGCACTTGCTTCATAAGCAAGACACAAAAAAGAATAA
TTCCTCCTTAGCTCAGTTGGTAGAGCGACGGACTGTTAATCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014040.1|WP_005381002.1|2656398_2656671_+|oxidative-damage-protection-protein	unknown	unknown	gnl|CDD|180059
NZ_CP014040.1|WP_025767645.1|2676224_2676530_-|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99906
NZ_CP014040.1|WP_065274864.1|2653333_2654362_-|DNA-methylase	unknown	unknown	gnl|CDD|223971
NZ_CP014040.1|WP_005381066.1|2676777_2678061_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|200570
NZ_CP014040.1|WP_104979714.1|2672330_2673086_-|chitin-disaccharide-deacetylase	unknown	unknown	gnl|CDD|235007
NZ_CP014040.1|WP_025768824.1|2659036_2660662_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|223910
NZ_CP014040.1|WP_192947883.1|2674802_2676137_-|PTS-transporter-subunit-EIIC	unknown	unknown	gnl|CDD|224372
NZ_CP014040.1|WP_033906218.1|2671226_2672225_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380494
NZ_CP014040.1|WP_005381001.1|2656748_2657888_+|membrane-bound-lytic-murein-transglycosylase-MltC	unknown	unknown	gnl|CDD|183271
NZ_CP014040.1|WP_104979712.1|2651046_2652225_+|radical-SAM-family-heme-chaperone-HemW	unknown	unknown	gnl|CDD|235550
NZ_CP014040.1|WP_017635575.1|2655302_2656379_+|A/G-specific-adenine-glycosylase	unknown	unknown	gnl|CDD|182805
NZ_CP014040.1|WP_005384506.1|2654379_2655099_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl|CDD|234649
NZ_CP014040.1|WP_192947881.1|2661650_2663087_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143421
NZ_CP014040.1|WP_104979710.1|2650425_2651028_+|XTP/dITP-diphosphatase	unknown	unknown	gnl|CDD|234648
NZ_CP014040.1|WP_005381010.1|2649875_2650307_+|DUF4426-domain-containing-protein	unknown	unknown	gnl|CDD|379616
NZ_CP014040.1|WP_005381029.1|2669842_2671096_-|HD-GYP-domain-containing-protein	unknown	unknown	gnl|CDD|225116
NZ_CP014040.1|WP_005381048.1|2673104_2674427_-|6-phospho-beta-glucosidase	unknown	unknown	gnl|CDD|133432
NZ_CP014040.1|WP_031777269.1|2674439_2674751_-|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl|CDD|224364
NZ_CP014040.1|WP_005381007.1|2652314_2653235_-|glutaminase-B	unknown	unknown	gnl|CDD|234880
NZ_CP014040.1|WP_005381011.1|2649457_2649748_+|YggU-family-protein	unknown	unknown	gnl|CDD|179931

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP014040.1|WP_005381002.1|2656398_2656671_+|oxidative-damage-protection-protein	gnl|CDD|180059	PRK05408, PRK05408, oxidative damage protection protein; Provisional.	2.80095e-59
NZ_CP014040.1|WP_025767645.1|2676224_2676530_-|PTS-sugar-transporter-subunit-IIB	gnl|CDD|99906	cd05564, PTS_IIB_chitobiose_lichenan, PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N,N-diacetylchitobiose-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. In the chitobiose system, these subunits are expressed as separate proteins from chbA, chbB, and chbC of the chb operon (formerly the cel (cellulose) operon). In the lichenan system, these subunits are expressed from licA, licB, and licC of the lic operon. The lic operon of Bacillus subtilis is required for the transport and degradation of oligomeric beta-glucosides, which are produced by extracellular enzymes on substrates such as lichenan or barley glucan. The lic operon is transcribed from a gammaA-dependent promoter and is inducible by lichenan, lichenan hydrolysate, and cellobiose. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.05599e-45
NZ_CP014040.1|WP_065274864.1|2653333_2654362_-|DNA-methylase	gnl|CDD|223971	COG1041, COG1041, Predicted DNA modification methylase [DNA replication, recombination, and repair].	2.25681e-08
NZ_CP014040.1|WP_005381066.1|2676777_2678061_+|polysaccharide-deacetylase-family-protein	gnl|CDD|200570	cd10946, CE4_Mll8295_like, Putative catalytic NodB homology domain of uncharacterized Mll8295 protein encoded from Rhizobium loti and its bacterial homologs. This family is represented by a putative polysaccharide deacetylase Mll8295 encoded from Rhizobium loti. Although its biological function still remains unknown, Mll8295 shows high sequence homology to the catalytic domain of Streptococcus pneumoniae polysaccharide deacetylase PgdA (SpPgdA), which is an extracellular metal-dependent polysaccharide deacetylase with de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. Both Mll8295 and SpPgdA belong to the carbohydrate esterase 4 (CE4) superfamily. This family also includes many uncharacterized bacterial polysaccharide deacetylases.	3.64002e-70
NZ_CP014040.1|WP_104979714.1|2672330_2673086_-|chitin-disaccharide-deacetylase	gnl|CDD|235007	PRK02134, PRK02134, chitin disaccharide deacetylase.	1.71974e-124
NZ_CP014040.1|WP_025768824.1|2659036_2660662_+|methyl-accepting-chemotaxis-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.01442e-61
NZ_CP014040.1|WP_192947883.1|2674802_2676137_-|PTS-transporter-subunit-EIIC	gnl|CDD|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	9.01684e-153
NZ_CP014040.1|WP_033906218.1|2671226_2672225_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380494	cd06270, PBP1_GalS-like, ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism. Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism. Transcription of the galactose regulon genes is regulated by Gal iso-repressor (GalS) and Gal repressor (GalR) in different ways, but both repressors recognize the same DNA binding site in the absence of D-galactose. GalS is a dimeric protein like GalR,and its major role is in regulating expression of the high-affinity galactose transporter encoded by the mgl operon, whereas GalR is the exclusive regulator of galactose permease, the low-affinity galactose transporter. GalS and GalR are members of the LacI-GalR family of transcription regulators and both contain the type 1 periplasmic binding protein-like fold. Hence, they are homologous to the periplasmic sugar binding of ABC-type transport systems.	3.85655e-114
NZ_CP014040.1|WP_005381001.1|2656748_2657888_+|membrane-bound-lytic-murein-transglycosylase-MltC	gnl|CDD|183271	PRK11671, mltC, membrane-bound lytic murein transglycosylase MltC.	8.90498e-147
NZ_CP014040.1|WP_104979712.1|2651046_2652225_+|radical-SAM-family-heme-chaperone-HemW	gnl|CDD|235550	PRK05660, PRK05660, radical SAM family heme chaperone HemW.	0
NZ_CP014040.1|WP_017635575.1|2655302_2656379_+|A/G-specific-adenine-glycosylase	gnl|CDD|182805	PRK10880, PRK10880, adenine DNA glycosylase.	0
NZ_CP014040.1|WP_005384506.1|2654379_2655099_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl|CDD|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.04237e-109
NZ_CP014040.1|WP_192947881.1|2661650_2663087_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143421	cd07103, ALDH_F5_SSADH_GabD, Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like. Succinate-semialdehyde dehydrogenase, mitochondrial (SSADH, GabD, EC=1.2.1.24) catalyzes the NAD+-dependent oxidation of succinate semialdehyde (SSA) to succinate. This group includes the human aldehyde dehydrogenase family 5 member A1 (ALDH5A1) which is a mitochondrial homotetramer that converts SSA to succinate in the last step of 4-aminobutyric acid (GABA) catabolism. This CD also includes the Arabidopsis SSADH gene product ALDH5F1. Mutations in this gene result in the accumulation of H2O2, suggesting a role in plant defense against the environmental stress of elevated reactive oxygen species.	0
NZ_CP014040.1|WP_104979710.1|2650425_2651028_+|XTP/dITP-diphosphatase	gnl|CDD|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	4.9665e-123
NZ_CP014040.1|WP_005381010.1|2649875_2650307_+|DUF4426-domain-containing-protein	gnl|CDD|379616	pfam14467, DUF4426, Domain of unknown function (DUF4426). Members of this entry are found mostly in g-proteobacteria, especially in Vibrio. Strangely enough, there seems to be one eukaryotic homolog in Nematostella vectensis (NEMVEDRAFT_v1g226006), where the PA0388-like domain is fused with a domain homogous to the Methionine biosynthesis protein MetW (see below). In several Pseudomonas species, but also in Vibrio vulnificus and Azotobacter vinelandii PA0388 homologs are genomic neighbors of Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) and Methionine biosynthesis protein MetW. On the other hand, in most Vibrio species it appears as a part of a conserved operon involved in possible response to stress.	4.01664e-66
NZ_CP014040.1|WP_005381029.1|2669842_2671096_-|HD-GYP-domain-containing-protein	gnl|CDD|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	2.25733e-72
NZ_CP014040.1|WP_005381048.1|2673104_2674427_-|6-phospho-beta-glucosidase	gnl|CDD|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP014040.1|WP_031777269.1|2674439_2674751_-|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl|CDD|224364	COG1447, CelC, Phosphotransferase system cellobiose-specific component IIA [Carbohydrate transport and metabolism].	6.82212e-37
NZ_CP014040.1|WP_005381007.1|2652314_2653235_-|glutaminase-B	gnl|CDD|234880	PRK00971, PRK00971, glutaminase; Provisional.	0
NZ_CP014040.1|WP_005381011.1|2649457_2649748_+|YggU-family-protein	gnl|CDD|179931	PRK05090, PRK05090, hypothetical protein; Validated.	6.04131e-59

Protein sequences

>NZ_CP014040.1|WP_005381001.1|2656748_2657888_+|membrane-bound-lytic-murein-transglycosylase-MltC
MKKIVFIAAALLMAGCSREFVEKIYDVNYEPTNRFANNLAELPGQFEKDTAALDALINSFSGNIQKRWGKKEIKYAGKSNYVKYIDNYLSRAEVDFRKGVITIETVSPTEPQKHLKDAIVTTLLTPDDPAHVDLFSSKGITLEGQPFLYKQVVDQDNKPIQWSWRANRFAEYLIANKIKTKNVDFKKAYYVEIPMVEDHFSTRSYQYADIVRRASKKYDIPEDLIYAIIKTESSFNPYAVSWANAYGLMQVVPKTAGRDVFKLVKKRSGQPSPEYLFNPENNIDTGTAYFYILKNRYLREVRHPTSLEYSMISAYNGGTGGVLNTFHRSDRKRAMQDLNSLQPNQVYWALTKKHPNAEARRYLEKVTNFKKEFNSKQTL
>NZ_CP014040.1|WP_005381002.1|2656398_2656671_+|oxidative-damage-protection-protein
MSRTVFCARLKKEGEGLDFQLYPGELGKRIFDNISKEAWAQWQHKQTMLINEKKLNMMDPEHRKLIETEMVNFLFEGKDVHIEGYTPPSE
>NZ_CP014040.1|WP_017635575.1|2655302_2656379_+|A/G-specific-adenine-glycosylase
MTPFASAILEWYDAYGRKDLPWQQNKTAYSVWLSEIMLQQTQVTTVIPYYQRFLERFPTVIDLANAEQDEVLHLWTGLGYYARARNLHKAAQEVASTYNGEFPLDIEKMNALPGIGRSTAAAILSSVYKQPHAILDGNVKRTLSRCFAVAGWPGQKKVENQLWEIAETHTPQTDVDKYNQAMMDMGAMVCTRSKPKCSLCPVADLCVAKQQGNVLDYPGKKPKKDKPIKQTRFVMLHHNTENGHEVWLEQRPQTGIWGGLFCFPQTEHVDAESDIELLLDQRGIQASNIKQKQTLITFRHTFSHYHLDITPILIDLSKQPDVIMEGNKGLWYNLSKPEEVGLAAPVKLLLETLPHELR
>NZ_CP014040.1|WP_005384506.1|2654379_2655099_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSEVTTNEYNEDGKLIRKIRSFVRREGRLTKGQESAMNECWPTMGIDFKAELLDWKEVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFIGIEVHSPGVGACLADAREAGITNLRVMCHDAVEVFEHMIPNGSLSTLQLFFPDPWHKKRHHKRRIVQLGFAEMVREKLIPNEGIFHMATDWENYAEHMIEVMNQAPGFENIAKDGDFVPRPDDRPLTKFEARGHRLGHGVWDIKYKRIA
>NZ_CP014040.1|WP_065274864.1|2653333_2654362_-|DNA-methylase
MYHYAILANPGHNRIYFDSAMTIACSELKAILASQGVDVTEIGSKDVGLPAALVFSCQEALTDEQARRIAASSIYYALFEVREDGLLRPVQAPVFNTFPESMSQILRYTGKTNEQFTRLMVNIGISASNTGSEQLTLMDPMCGKGTTLFEGLIHGLNVVGVEINAKWVQEIQTFIVKFMKNGRFKHKVSKEKRTAGGKKVADGFVVEAAANKEDYNQGHLQFMKLYSADTRIADQVVKKNSVDVMVSDLPYGVQHGSKNAKDSKLNRSPLELLKEALPAWKVVLKKQGSVVLSFNEFTLKWKDVAALFEEQGWKVLSEEPYIGYLHRVDQSINRNIIVAVKP
>NZ_CP014040.1|WP_005381007.1|2652314_2653235_-|glutaminase-B
MKPTVEILTDILAEVRPLIGQGKVADYIPALAKVPSNKLGIAVYTNEGEVIKAGDADEPFSIQSISKALSLTLAMCLYKQEEIWSRVGKEPSGQAFNSLIQLEMEQGIPRNPFINAGAIVVADLLQTRLSAPRQRLLEFVRQLSGDTHIVYDKVVAASEMMHGDRNAAIAYLMRSFGNFENEVIPVLQNYFHACALKMSCVDLAKTFSYLANKGTSVQTGKPVVSPVQTKQLNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTISVWSPELDPSGNSLAGTKALELLSERIGRSIF
>NZ_CP014040.1|WP_104979712.1|2651046_2652225_+|radical-SAM-family-heme-chaperone-HemW
MLTPPALSLYVHIPWCVQKCPYCDFNSHALKTEIPEEEYISALLEDLDTDIEKYRLNEAPRPLHSIFIGGGTPSLISAEGIEHLLKGIEARIPFKPEIEITMEANPGTIEAERFVGYRKAGVTRISIGVQSFEQQKLERLGRIHGQDEAVNAAKLAHQIGLNSFNLDLMHGLPDQSIEQALADLDKAIELAPPHLSWYQLTIEPNTMFYYKPPTLPDDDDLWDIFELGHQKLAAAGYVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGSHGKLSFTDGRIIRTTKVKHPRGYLAAYQNMVKPYLHTEHVVADEDRPFEFFMNRFRLIEACPKQDYVDTTGLPLSTIQETINWAIEMGYLSETPTHWQITEKGKLFLNDLLEAFMAEESEE
>NZ_CP014040.1|WP_104979710.1|2650425_2651028_+|XTP/dITP-diphosphatase
MKKIVLATGNQGKVREMADLLSDFGFEVLAQSEFNVSEVAETGTTFIENAIIKARHAAQETGLPAIADDSGLEVDFLKGAPGIYSARYAGESASDQENLEKLLAAMEGVPEAERTARFHCVLVLMRHENDPTPIVCHGKWEGRILTEAHGENGFGYDPIFFVPEDNCASAELEPAHKKQLSHRGKALKSLFAQLSEQVSQ
>NZ_CP014040.1|WP_005381010.1|2649875_2650307_+|DUF4426-domain-containing-protein
MSKWITALLISLLSLPSFADQFKNMKDIEVHYVAFNSTFLTPKVARSYDIKRNGYLAVVNISVLDRASLGKPALEAKIAGRAKNLIGQTQTLTFREVKEGNAIYYLAELPITHEETFTFDIDVKAGNKGSGKLKFTQKFYVEE
>NZ_CP014040.1|WP_005381011.1|2649457_2649748_+|YggU-family-protein
MSAAVWQDGEDIILKLYIQPKASRDKIVGLHGEELKIAITAPPVDGKANAHLTKFLAKQFKIAKGLVHIEKGELGRHKQIRIESPTQIPTEIKAII
>NZ_CP014040.1|WP_025768824.1|2659036_2660662_+|methyl-accepting-chemotaxis-protein
MKLKTQAYLLSAIILLALLALTATGLWTLRVASNLDNKARVTELFKSAYSILTEVEKMAIEGKMPEDEAKALATRLLRNNIYKDNEYVYVADENMMFIAAPLDPQLHGTSFHDFRDGSGNSVGQLILDVLGHKTGQIVEYTWSQKQADGSIEEKHSIAEKTPHWGWVVGTGIGFNEVNARFWSTAQWQLVLCLIIAGSILSGLIISIRKMLHLLGGEPNDVRKAVQAVAQGDIQTSFDTVAPRGSIYRAVQDMSQSLATMVTNLEKSMHALRAELFAVESRSNTIADLTVSQQQSTAMIATAMTEMASSANHVANSASDTANNTDEADKQSQHTQKLIHNTVENIQGLASQLNTASKAVADLDQDVNNIVKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQDSTKEIQYMISNLQEGSRNAIHTMEICAETSESTVTESKNASEALQQIVTALESITTMSQQIATAAAEQTQVSDDIALRINLIEESGGQLNSVVTESQSSTQSLASLANELEGWVNKFSVKH
>NZ_CP014040.1|WP_192947881.1|2661650_2663087_-|aldehyde-dehydrogenase-family-protein
MMQQIKNETLKSVFKQWSSEEGIVVINPATEQELIRLKPSTLDELDDLIGQCKTEQVRWAKLSAKERSRRLRGWYQLLLDNAEDIATIITLEQGKPLAESKGEVMYGASFVEWFSEEAKRAYGEVIPAPTTDRRLSAIRQPVGVCAAITPWNFPIAMITRKAAPALAAGCGMLIKPSELTPLTAIAVVELAYQAGIPKELLSVVVSEQAAEFGQVLSTDPRIQKISFTGSTRVGKILMKQASDSVKAVSMELGGNAPFIVFEDADLDAAAEGLVASKFRNAGQTCVCTNRLYVHKNVKQAFIDKVLSKLSKLKLGNGLEKGVTLGPVITMASKHRLEAVIDQAVQEGASIANSPQRLPGRFMEPVLLDSVTQNMSIVQQELFGPVLPIVTFENDDQVLEMANDTEYGLACYFYTNSLKRIVTFSEGLEYGMVGVNEGIISTEVAPFGGVKESGVGREGAKQGLDEYLETKYICLGGLS
>NZ_CP014040.1|WP_005381029.1|2669842_2671096_-|HD-GYP-domain-containing-protein
MAAIKLTVDRIQPGLHIRLPLKWNDHPFLLNSFKIKDQEQVEMIRHLGVKFVYFNPEQSDAVPLPVDQRQADRVTNEASLDHETQKMWQEKQNRIEKLSAYRRRVIQCEKEFERSLARMRSVMTKIRNRPTAAVDEAKLLIEDIVEKLMCDDNVTLHLMNGKNEFEDIYFHSLNVAVISMMIGRAKGYSAAQLKELSFSALFHDIGKIKIPTAILRKQLPLTEPETNYLKLHTKYGVDLASQIEAFPEVARIVIAQHHELRDGSGYPKGLKGDEINEFAQIIAVANAFDNLCHTPIVSDQKIPYTALSHLYKNCKHLYKEENLNILIKFMGVFPPGTVVQLSNNMVGLVISVNASHLLFPNVLVYDPSVPRTQAPIIDLASKDIKIVNAIHPSKLPDKVKEYLNPRSRISYFFDSDE
>NZ_CP014040.1|WP_033906218.1|2671226_2672225_-|LacI-family-DNA-binding-transcriptional-regulator
MARIKDVAELAGVNRSTVSRIINGEGKFREETRKKVEQAMAQLNYRPSAIARSLATSSSNMVGLLVTYYTGGFFGEMMEQVQTELDIHKKFLITAQGHHSAQGEKEAIQRFNDLRCDGYVLHSRYLSDDDLRELAKQPTPFVLLDRYVEGIEERCVTFNHHHASRIAVEHLLAGGHRKIACITGPSQRHNSVLRKLGYIDAMKDAGIDIDESWCEEGNYGRQSGYDAMAAILQRHPDVTAVFSCSEEMTVGAMQYLHEHSISVPEQISLTSFDSVDLCESLYPTVSAVHFPISDMARVAVQTLMGLVKEQEVIDKPVFEAKLKIRKADRSLK
>NZ_CP014040.1|WP_104979714.1|2672330_2673086_-|chitin-disaccharide-deacetylase
MKVIFNADDFGLTRGVNSGIVKAHQQGVVHSTTMMVGMDAEQHALELARHNPDLKIGVHLRFTAGVPITKHPNLTNGRAHFINYDELWSKQDFETQVIYDEAKAQVEHFLSLGLELSHLDSHHHAHTHPQILPVIKEVANEYRVPLRGTGLCQESMTIRYIFTDEFYDQKVSLDGLMTHLLSLKADYDLVEVMCHPAEADQALILKSGYALQRELELQVLTSPILKEQLAHHGIAVTDYSELVSTNQMVGV
>NZ_CP014040.1|WP_005381048.1|2673104_2674427_-|6-phospho-beta-glucosidase
MSREAIKLAIIGGGSSYTPELVEGVIKRLEYLPVKKIHFVDIESGAEKLEIIKGLAQRMVDKAGAKIEIKAGFDRRAAIKDADFVMTQFRVGGLAARANDERIPIKYDVIGQETTGPGGFAKALRTIPVILDICKDIEELAPNAWMLNFTNPAGLVSEAVSKYTKVKSIGLCNVPVSMEMMIAEMMECEPKELQLEFAGLNHLVWVHKAWLNGEDITQTVLEKVGDGANFSMKNIWEEPWDPAFLKALGAIPCPYHRYFYQTDAMLAEEKQSADEKGTRAEQVMETENALFKLYQDPTLDHKPKELEERGGAYYSDASLNLVDSIYNNRNSIHVVNVLNNGAINGLPDDAVIECSAVIGSWGAKPLAVGELSNNIKGLLHQVKAYEQLTIEAAVEGNYDKALMALTNNPLVPDIGRAKSILDDILAVNAPYLPQFKLTTL
>NZ_CP014040.1|WP_031777269.1|2674439_2674751_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MEQELVVMEIICNAGEARSLSYEALRLSREQDFEAADEKLSQARECINKAHLIQTQLIEEDQGEGKVPMTLVMVHAQDHLMTTILAQEMAVEIVALNKKISNK
>NZ_CP014040.1|WP_192947883.1|2674802_2676137_-|PTS-transporter-subunit-EIIC
MKLYDAIISAVEKHIAPIAAKVGNQPHVRAMRDGFIVAMPFIIVGSFILIFAFPPFAEDTTFTFGRIWLDFATTHFDTIMMPYNMSMGIMTIFVSLGVAYSLAKAYKMDGITSAVLSLMSFLLIAAPAKDGALSMSHMGGTGIFTAVMCAFFSVELYRFMKKHNITIRMPEQVPPAIARSFEVLLPVLAIFITLYPLSLFVQTQYDMLIPDAVMAIFKPLISASNSLPAIIGALLLCQLLWFAGIHGAAIVVGLLSPIFLTNIGANIEAFVAGEPIPNVFTQPFWDFYIFIGGSGATLALVMLMSFSRSVHLKSIGRMSAVPGFFQINEPVIFGSPVVMNPTLFIPFVFAPVINATIAYFAVHVGFVGMGVATTPWTTPALIGASWGSGWTFAPVLLVIGLLILDLIIYFPFFKMFEKQMLEQELPTTKEAKGDTQPSGEGVTA
>NZ_CP014040.1|WP_025767645.1|2676224_2676530_-|PTS-sugar-transporter-subunit-IIB
MKKILLCCSAGMSTSMLVKKMEQAAENKGIECKIDAMSVNAFEDAIKEYDVCLLGPQVRFQLEELRKTAQEHGKNIDAISPQHYGMMKGEEVLEQALELIN
>NZ_CP014040.1|WP_005381066.1|2676777_2678061_+|polysaccharide-deacetylase-family-protein
MKFNKLAIATLVSAALSQHSFAQTDSKGTIYLTFDDGPINASIDVIQVLNQEDIKATFYFNAWHLDGIGDENEDRSLEALKLALDTGHIVANHSYDHMVHNCVDEFGPNSAAECNATGDHQLNSYQDPVYDASMFTENLSVLAKYLPNITSYPNYKATEFARLPYTNGWRVTKDFKADGLCATSDDLKPWEPGYVCDTSNPSNSVKAAIEVQNILANNGYQTHGWDVDWAPENWGIEMPANSLTEAEAFLGYVDSALNTCAPTTINPINSKAQEFPCGTPLHADKVIVLTHEFLFEDGKRGMGATQNLPKLAKFIQLAKQAGYDFDTMDNYTPNWQVGHNYDAGDYVLHLGTVYQAVTNHTAQQDWAPSPTSSLWTNADPATNWTQNVSYKQGDVVTYQGLRYLVDVPHVSQADWTPNTQNTLFTAL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP014040.1	2658173-2658209	0	1.0
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP014040.1	3011492-3011528	0	1.0
NZ_CP014040_1	1.2|2658610|75|NZ_CP014040|PILER-CR	2658610-2658684	75	NZ_CP014040.1	2658256-2658330	17	0.773

1. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to position: 2658173-2658209, mismatch: 0, identity: 1.0

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccattc	Protospacer
*************************************

2. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to position: 3011492-3011528, mismatch: 0, identity: 1.0

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccattc	Protospacer
*************************************

3. spacer 1.2|2658610|75|NZ_CP014040|PILER-CR matches to position: 2658256-2658330, mismatch: 17, identity: 0.773

cgtgtcggtggttcgattccgcctcgaggcaccatatctggtgcacttgcttcataagca	CRISPR spacer
cgtgtcggtggttcgattccgcctcgaggcaccatatttggtgaacttgcttcataagca	Protospacer
*************************************.***** ****************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	296499-296535	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_LN868946	Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence	103821-103857	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	KU052038	Escherichia phage SerU-LTIIb, partial genome	1164-1200	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	KU052038	Escherichia phage SerU-LTIIb, partial genome	3070-3106	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	LN997803	Escherichia coli phage phi467	15126-15162	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP022660	Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence	52078-52114	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP045061	Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence	52084-52120	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP045054	Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence	52089-52125	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP045058	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence	52088-52124	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NC_021742	Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence	35428-35464	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	MH791411	UNVERIFIED: Escherichia phage Ecwhy_1, complete genome	13645-13681	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	MH494197	Escherichia phage CMSTMSU, complete genome	196772-196808	2	0.946
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP023526	Cedecea neteri strain FDAARGOS_392 plasmid unnamed, complete sequence	1927-1963	3	0.919
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NZ_CP054057	Scandinavium goeteborgense strain CCUG 66741 plasmid pSg66741_1, complete sequence	85817-85853	3	0.919
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	KY653118	Morganella phage IME1369_01, complete genome	698-734	4	0.892
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	LC494302	Escherichia phage SP27 DNA, complete genome	76611-76647	5	0.865
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	17117-17153	5	0.865
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NC_027364	Escherichia phage PBECO 4, complete genome	207832-207868	5	0.865
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	NC_049942	Escherichia phage JLK-2012, complete sequence	23524-23560	5	0.865
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	52945-52981	6	0.838
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	MH383160	Escherichia phage UB, complete genome	272124-272160	6	0.838
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	MK327931	Escherichia phage vB_EcoM_G17, complete genome	77929-77965	6	0.838
NZ_CP014040_1	1.1|2658527|37|NZ_CP014040|PILER-CR	2658527-2658563	37	KM507819	Escherichia phage 121Q, complete genome	77938-77974	7	0.811

1. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccatat	Protospacer
*********************************** .

2. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_LN868946 (Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccatca	Protospacer
***********************************. 

3. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to KU052038 (Escherichia phage SerU-LTIIb, partial genome) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccatat	Protospacer
*********************************** .

4. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to KU052038 (Escherichia phage SerU-LTIIb, partial genome) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccatat	Protospacer
*********************************** .

5. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to LN997803 (Escherichia coli phage phi467) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccatat	Protospacer
*********************************** .

6. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_CP022660 (Salmonella enterica subsp. enterica strain RM11060 plasmid pRM11060-2, complete sequence) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccactt	Protospacer
**********************************.*.

7. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_CP045061 (Salmonella enterica subsp. enterica serovar Muenchen strain LG26 plasmid pLG26p2, complete sequence) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccactt	Protospacer
**********************************.*.

8. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_CP045054 (Salmonella enterica subsp. enterica serovar Muenchen strain LG24 plasmid pLG24p2, complete sequence) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccactt	Protospacer
**********************************.*.

9. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_CP045058 (Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccactt	Protospacer
**********************************.*.

10. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NC_021742 (Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagccggcaccaatc	Protospacer
*************************.******** **

11. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to MH791411 (UNVERIFIED: Escherichia phage Ecwhy_1, complete genome) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcacaaatc	Protospacer
******************************** * **

12. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to MH494197 (Escherichia phage CMSTMSU, complete genome) position: , mismatch: 2, identity: 0.946

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcacaaatc	Protospacer
******************************** * **

13. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_CP023526 (Cedecea neteri strain FDAARGOS_392 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.919

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccagaa	Protospacer
**********************************   

14. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NZ_CP054057 (Scandinavium goeteborgense strain CCUG 66741 plasmid pSg66741_1, complete sequence) position: , mismatch: 3, identity: 0.919

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgattccggtagtcggcaccaaat	Protospacer
**********************************  .

15. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to KY653118 (Morganella phage IME1369_01, complete genome) position: , mismatch: 4, identity: 0.892

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
taggtcaccagttcgactccggtagccggcaccatat	Protospacer
****************.********.********* .

16. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 5, identity: 0.865

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
aaggtcaccagttcgattccggtagtcggcacaaaat	Protospacer
 ******************************* *  .

17. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 5, identity: 0.865

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
aaggtcaccagttcgattccggtagtcggcacaaaat	Protospacer
 ******************************* *  .

18. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 5, identity: 0.865

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
aaggtcaccagttcgattccggtagtcggcacaaaat	Protospacer
 ******************************* *  .

19. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to NC_049942 (Escherichia phage JLK-2012, complete sequence) position: , mismatch: 5, identity: 0.865

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
caggtcgccagttcgattccggtagccggcaccatat	Protospacer
.*****.******************.********* .

20. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 6, identity: 0.838

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
aatgtcaccagttcgattccggtagtcggcacaaaat	Protospacer
 * ***************************** *  .

21. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 6, identity: 0.838

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
aatgtcaccagttcgattccggtagtcggcacaaaat	Protospacer
 * ***************************** *  .

22. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 6, identity: 0.838

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
aatgtcaccagttcgattccggtagtcggcacaaaat	Protospacer
 * ***************************** *  .

23. spacer 1.1|2658527|37|NZ_CP014040|PILER-CR matches to KM507819 (Escherichia phage 121Q, complete genome) position: , mismatch: 7, identity: 0.811

taggtcaccagttcgattccggtagtcggcaccattc	CRISPR spacer
aatgtcaccagttcaattccggtagtcggcacaaaat	Protospacer
 * ***********.***************** *  .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	447800 : 454584	7	Staphylococcus_phage(50.0%)	NA	NA
DBSCAN-SWA_2	2578064 : 2595238	15	uncultured_Mediterranean_phage(18.18%)	tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP014040|447800:454584|DBSCAN-SWA
CATGACAACGAATCAACAAAATGCAGTTGTTTCACAACCACAAACTGTCGTTGTGAAACTGGGTACAAGTGTGCTGACAGGCGGCACTCTGGCACTCGACCGTGCACACATGGTTGAGTTAGCACGCCAGTGTGCTGAGCTTAAAAAACAAGGCCATTCAATCGTAATGGTTTCGTCTGGTGCGATTGCAGCAGGCCGTGAGCATCTTGGTTACCCCGCATTGCCCAACGAGATGGCGAGTAAGCAGTTACTTGCCGCGGTGGGGCAGAGCCGCTTGATTCAAACATGGGAGTCTTTGTTTGGTATTTATGGTATCAAGATCGGCCAAATGTTACTAACCCGTGCCGATTTAGAAGATCGTGAGCGATTCCTTAACGCGCGTGACACTATTAATGCGCTCGTCGCGAACGATATTGTTCCTATCGTAAACGAAAATGATGCCGTTGCGACTAGCGAGATTAAAGTTGGCGATAACGACAACCTTTCCGCTTTGGTAGGCATTTTATGTGGTGCAGATAAGCTCTTGCTTTTAACGGACCAAAAAGGTCTGTTTACTGCTGACCCTCGTAAAGATCCGAACGCAGAGCTTATCAAGGAAGTAAAAACCATCGACGACACGCTGCGTAAAATCGCAGGTGGAAGCGGTACAACATTGGGTACTGGTGGTATGGCAACGAAGCTGCAAGCCGCAGACATCGCTCGCCGCGCAGGTATCGAGGTTATTATTGCTGCTGGTAGTGCGCCGAATGTTATCTTTGACTCTCTAAGTGCTGAACCTCAGGGCACGCGCTTCCTACCTTGCGCTGAAGCCTTAGAGAACCGTAAACGCTGGATTCTAGCGGGACCTGCGGCATCGGGCGACATCGTTATTGATGATGGTGCAGTCAATGCTGTGGTCGGCAAGGGGAGTAGCCTACTTGCTAAAGGGGTCATCAAAGTTAGTGGTGACTTCGCACGAGGCGAAGTGGCGCGTGTAACAAACGCTCACGGTAAGTTGGTGGCTCGTGGCATCAGCGCCTACTCAAGTGATGACCTAACTAAAATTACGGGCAAACACAGTAAAGATATCATCTCTATTTTGGGGCATGATTATGGCTCTGAGGTGATTCACCGCGATGATCTGGTCGTCATTCAGGAATAGAATTAGAGGGAAGCAAAGTGGATTTAACGAATATGGGTAAAGCTGCTAAAGATGCAGCTTTCGAATTAGCGACAGCGTCAACTGCGCAAAAGAACCAAGCATTAGCCATCATCGCTGATGAGCTAGAAGCAAACTCCGCTGCTATTTTGGCGGCAAACGCTAAAGACATCGAACTTGGCCGTGAAGCGGGTTTAACCGATGCGCTGCTCGATCGCCTTTTGCTTAATGAAGAACGATTGACTGCAATTGCGAATGATGTTCGCAACGTCATTAGCTTGAACGATCCTGTAGGCAGCGAAATAGACAGTAAGGTACTGGAAAATGGGATGTCACTGTCTCGTCGTCGTGTGCCGCTTGGTGTCGTAGGCGTAATTTATGAAGCGCGTCCAAACGTAACCATTGATATTGCAGCGTTGTGCTTGAAAACCGGCAACGCAAGCATTTTACGTGGTGGCAAAGAGACATTTTTCTCGAATATGGAATTAGTGAAGGTTATTCAGTCTGCGCTCGCAAAGGCGAACCTTCCAGCCGCTTCTGTGCAGTACATTGAAAAACCAGATCGTGAGCTTGTTTCTCAATTGCTTAAGTTGGACGATTACGTCGACATGATCATTCCACGCGGTGGTGCTGGCCTACACAAAATGTGTAAAGAAAACAGCACGATTCCGGTGATTATTGGTGGCTTTGGTATCAGCCATATCTTTGTCGACGAATCCGCTGATCTAGAGAAATCCCTGAATGTGGTTGAGAACTCTAAAGTTCAACGTCCATCTGCGTGTAACTCATTAGATACGCTGCTCGTGCATGAAAAAATTGCAGCGCAATTCCTACCAATGATCGTAGAGCGCATGAACGATAAAGTGACCTTCGTGACAGAGCCTAAGGCAAAAGCACTGATGGCTCAAGCAACACAAATTCGCGATGCTGTTGAAGGTGACTTTGATACGGAATGGTTGAGCTACACTCTTGGTGTAAAAGTTGTGTCTGATGTGAAAGATGCCATTGATCATATGCGTGTCCATAACGCGAGCCACTCAGATGCGATCATGACCAATAGTTTGGAAAACTCAGAACTGTTCATCAATTCTGTCGGTTCGGCGGCGGTTTATGTGAATGCTTCAACGCGCTTTACAGACGGTGCGCAATTTGGCCTTGGCGCAGAAGTCGCAGTATCTACGCAAAAGCTACATGCACGCGGTCCGATGGGCTTAGAAGAGCTAACTAGTTACAAGTGGGTTGGTAAAGCGAACTACTTAGCACGCAGTTAACACATTCGACGAGATCTTGAGTGAAAAAGGGGCCTTTGCGCCCCTTTTTGTTTTGTCTAACATACCAATTCCGCTACACTACATGAGCTTTTATTTCGGTTTGAAAGCGTTATACCCAAATAGCTTTAATAGAGTCCGTATAACCATGAACGCGTGGTTATCCGTGATTGCTCATGAGGTTATTTTGGTATAGATATGGAGGTGATATGCATTGTCCTTTTTGTTCCGAGAACGATACCAAAGTTATTGATTCCCGCTTAGTGGCTGATGGCCATCAAGTTCGACGTCGCCGTCAGTGCTTGGCGTGTAGCGAGCGTTTCACTACGTTTGAAAGCGCAGAGTTAGTGATGCCTAAAGTGATCAAATCGAATGGCAACCGTGAACCATTTGATGAAGATAAAATGGTTGGCGGTATTCAACGCGCTTTAGAGAAACGCCCAGTGAGTGCCGATTCTATAGAGTTAGCGATCAGTATGATCAAATCACAACTGCGTGCGACGGGTGAGCGAGAGGTTCCGAGTGAAATGATTGGTAATTTAGTCATGGACCAGCTCAAAGAGCTCGATAAGGTGGCTTACATTCGTTTCGCTTCCGTTTACCGAAGCTTTGAAGATATTCGCGAGTTTGGCGAAGAGATTGCCCGCCTAGAAGACTGAGTAGCTCATGACTCAACACACTCCTGAAAGAGCGTTTTCTGATTTAGATTTCGCCATGATGTCACGAGCTATTAAGTTAGCGAAACGTGGCATTTATACCACCGCCCCTAATCCAAATGTAGGGTGTGTCATCGTTCGTGATGAAGAAATTGTCGGTGAAGGCTATCACCATCGTGCTGGTGAGCCGCATGCCGAAGTGCACGCGATGCGCATGGCGGGTGAAAAAGCGGTTGGTGCAACCGCTTATGTGACGCTAGAACCTTGCTCTCATTACGGCCGTACACCGCCATGTGCCGAAGGGCTGATTAAAGCCAAAGTGGCACGTGTGGTTTGCGCCATGGTAGACCCAAACCCGAAAGTTGCAGGTCGCGGCATCCAGATGTTGCGTGATGCCGGAGTTGAAGTACAAATCGGCTTGTTAGAGCAAGATGCCCTTGCCCTTAACCCTGGTTTTATAAAGTACATGCGCACAGGCATGCCGTTTGTTCAATTAAAAATGGCAGCCAGTTTGGATGGGCAAAGCGCACTCAATAATGGTCAGAGCCAATGGATCACCTCCCCAGCGGCCCGCCAAGATGTGCAGCGTTATCGAGCAATGAGTGGTGGCATTCTTTCTACTAGCAAAACGGTGATTGATGATAATGCATCACTCAATGTGCGCTGGGATGACTTACCTAATAGTGTTCAAGCGCAGTATTTACAAGAAGAGCTTCGTCAACCAGTACGTGTAATCTTAGACCGTCAGAACCATTTAACTGATGCGCTCAAGCTGTTCCATACCGATGGAGAACGAGTTATTGTTCGCTCTGATGGAGACTGTATCCCTCTATTGGACAGCGCTGACCAAATTGAGTTATCAACGACATTAAAACGTATCTCTGATGAGCACCATATCAATCACTTATGGGTTGAAGCTGGAGCTACGCTAGCGAGTGCGATGATAAAGGCTAATCTTGTAGATGAGCTCATTGTTTACCTTGCGCCAAAACTCATGGGCAGCGATGGTCGGGGGCTTATCGGTGCTTTAGGGTTAAGCGCTATGGCTGACGTCATAGATTTAAACATTACAGACGTTCGTATGGTTGGGGTAGACATTCGCATCACCGCCACCATAAAACGTAATGAAATTAGATAAGAAATAGTATGTTTACAGGAATAGTAGAAGCAGTGGGCAAGTTAGCTGCGATTACGCCGAAGGGCGAAGACATCACCGTCACGGTTGAAACGGGTACGCTTGATATGTCAGACGTTAAGTTAGGCGATAGCATTGCGACCAATGGTGTTTGCTTAACGGTAGTTGACTTCGGAAGCCACTATTACAGTGCTGATCTGTCATTAGAAACCTTGAAGAAAACTGGGTTTGCTGATTACCAAGTAGGCGATAAGGTGAATCTAGAAAAAGCCATGTTGCCAACAACGCGATTGGGTGGACATATCGTTTCTGGCCATGTCGATGGGGTTGGTGAAATTGTCGAACGCAATTCAGTTGGCCGTGCGATAGAGTTTTGGGTTGCAATGCCTGCGGAAATTAGCAAGTACGTTGCAGAGAAAGGCTCGATTACTGTTGATGGTATTAGCCTAACCGTCAACGACTTACGTAAAAATGCTTTTAAGCTGACGATCGTTCCTCATACGAGTGAAGAAACTACGATTGACCAGTTTCAAGTGGGGCGCAAAGTCAACTTAGAAGTTGATGTACTTGCGCGTTATATGGAGCGTTTACTGCAAGGACAACAAGAAGATAAGGCCGAGTCTCGTATCACGATGGACTTTTTACAGCAAAACGGTTTTGCATAAGTCTTGGGAGTGGCTGCGTGAGGCATGCGATAAAGAGCAGACTCACAGAACACCGCGAGATTCATTGACTTGCTTAATGCAAAGCTCAAACTATTGACCTAACTAGCATTCACTGCAACGTAATTTTTCATTGCTGTCGCAATAACAAATTTAGAATAACGGGATAACAGACTATGCCAATCAGTACGCCACAAGAAATTATTGATGATATTCGCGCAGGCAAAATGGTCATCCTAATGGATGATGAAGACCGCGAGAATGAAGGTGACTTGATCATGGCTGCCGAGCATATTACGCCGGAAGCCATCAACTTTATGGCAACCTATGGCCGTGGCCTGATTTGTTTAACCATGACCAAAGATCGTTGCGAAAGTCTAGGTCTGCCACCAATGGTGCAAGACAATAATGCGCAATACACCACCAACTTTACTGTTTCGATTGAGGCAGCAGAAGGGGTAACGACTGGTATTTCAGCCGCAGATCGCGCACGTACCGTTCAAGCAGCAGTCGCGCCAAACGCTAAAGCTGCGGATTTGGTGCAGCCTGGTCACATCTTCCCTCTCGCAGCTCAAGACGGCGGTGTACTGACTCGCGCAGGTCACACTGAAGCTGGCTGTGATTTGGCTCGTCTTGCTGGTTTAGAGCCAGCATCGGTGATTGTTGAGATCTTAAATGACGACGGCACCATGGCTCGTCGCCCAGATCTAGAGATCTTTGCAGAGAAGCACGGTATTAAATTGGGCACTATTGCCGACCTAATTGAGTACCGCAATAACACTGAGACAACGATTGAACGTGTGGCAGAGTGCAAGCTACCGACAGAGTTTGGCGAGTTCACGTTAGTCACGTACAAAGACACCATTGATAACCAAGTGCACTACGCAATGTGCAAGGGCGATTTGAAAGAAAAAGCGCCACTGGTTCGCGTTCATCTTCAAGACGTTTTTACCGACTTACTACGTAGCGATCGTAATGCAGAGCGCAGCTGGACACTAGATAAGGCAATGAAACGCATTGGTGAAGAGGGCGGTGTACTGGTTGTTCTTGGCCATGAAGAATCGACCGATCTACTTATTCATCGCGTGAAGATGTTCGAAGCGCAAGACAAAGGTGAAGCACCAACGCTTGCTAAAAAACAAGGCACGTCTCGCCGTGTTGGCGTTGGTTCACAGATTCTTGCGGATCTCGGTGTACATGATATGCGTCTTCTGTCATCGACCAACAAAAAGTACCACGCGTTAGGTGGTTTTGGTCTGAACGTTGTTGAGTACGTCTGCGAGTAACAACCGAACAATAAGTTCCTAGTCTTTGACGTGCTTAACTCGTCAATGGCTAGGAACCGGTGATTTGCCTCCAATTTCCATTAGATATTGCTCACAAAATTGTGCTAGAATCCGGCGATTCTCACTTGATGAACATATTTCACTTATAAATAGAGTTAAAGGAAAGCTTATGAAAGTGATCGAGGGTGGCTTCCCAGCGCCAAATGCAAAAATTGCTATCGTTATTTCTCGTTTCAACAGTTTTATTAACGAAAGCCTACTTTCTGGTGCGATCGATACACTAAAGCGTCACGGACAAGTAAGCGAAGACAACATCACGGTTGTGCGTTGTCCAGGTGCCGTAGAACTACCTCTAGTAGCTCAGCGTGTTGCTAAAACTGGCAAATTCGACGCTATTGTTTCTCTAGGGTCTGTTATTCGCGGTGGAACGCCTCACTTTGACTATGTTTGTAGTGAAATGAACAAAGGTCTAGCACAAGTGTCTATGGAATTCAGCATTCCAGTAGCATTTGGTGTTTTGACTGTTGATACGATCGATCAAGCGATTGAACGCGCAGGAACCAAGGCTGGTAATAAAGGTGCAGAGGCTGCACTAAGCGCACTTGAAATGATTAATGTACTATCTGAAATTGATTCCTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP014040|447800:454584|448957_450208_+|WP_104978847.1|DBSCAN-SWA
MDLTNMGKAAKDAAFELATASTAQKNQALAIIADELEANSAAILAANAKDIELGREAGLTDALLDRLLLNEERLTAIANDVRNVISLNDPVGSEIDSKVLENGMSLSRRRVPLGVVGVIYEARPNVTIDIAALCLKTGNASILRGGKETFFSNMELVKVIQSALAKANLPAASVQYIEKPDRELVSQLLKLDDYVDMIIPRGGAGLHKMCKENSTIPVIIGGFGISHIFVDESADLEKSLNVVENSKVQRPSACNSLDTLLVHEKIAAQFLPMIVERMNDKVTFVTEPKAKALMAQATQIRDAVEGDFDTEWLSYTLGVKVVSDVKDAIDHMRVHNASHSDAIMTNSLENSELFINSVGSAAVYVNASTRFTDGAQFGLGAEVAVSTQKLHARGPMGLEELTSYKWVGKANYLARS
>NZ_CP014040|447800:454584|452834_453944_+|WP_005381573.1|DBSCAN-SWA
MPISTPQEIIDDIRAGKMVILMDDEDRENEGDLIMAAEHITPEAINFMATYGRGLICLTMTKDRCESLGLPPMVQDNNAQYTTNFTVSIEAAEGVTTGISAADRARTVQAAVAPNAKAADLVQPGHIFPLAAQDGGVLTRAGHTEAGCDLARLAGLEPASVIVEILNDDGTMARRPDLEIFAEKHGIKLGTIADLIEYRNNTETTIERVAECKLPTEFGEFTLVTYKDTIDNQVHYAMCKGDLKEKAPLVRVHLQDVFTDLLRSDRNAERSWTLDKAMKRIGEEGGVLVVLGHEESTDLLIHRVKMFEAQDKGEAPTLAKKQGTSRRVGVGSQILADLGVHDMRLLSSTNKKYHALGGFGLNVVEYVCE
>NZ_CP014040|447800:454584|450871_451999_+|WP_104978849.1|DBSCAN-SWA
MTQHTPERAFSDLDFAMMSRAIKLAKRGIYTTAPNPNVGCVIVRDEEIVGEGYHHRAGEPHAEVHAMRMAGEKAVGATAYVTLEPCSHYGRTPPCAEGLIKAKVARVVCAMVDPNPKVAGRGIQMLRDAGVEVQIGLLEQDALALNPGFIKYMRTGMPFVQLKMAASLDGQSALNNGQSQWITSPAARQDVQRYRAMSGGILSTSKTVIDDNASLNVRWDDLPNSVQAQYLQEELRQPVRVILDRQNHLTDALKLFHTDGERVIVRSDGDCIPLLDSADQIELSTTLKRISDEHHINHLWVEAGATLASAMIKANLVDELIVYLAPKLMGSDGRGLIGALGLSAMADVIDLNITDVRMVGVDIRITATIKRNEIR
>NZ_CP014040|447800:454584|450414_450864_+|WP_005381578.1|DBSCAN-SWA
MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACSERFTTFESAELVMPKVIKSNGNREPFDEDKMVGGIQRALEKRPVSADSIELAISMIKSQLRATGEREVPSEMIGNLVMDQLKELDKVAYIRFASVYRSFEDIREFGEEIARLED
>NZ_CP014040|447800:454584|447800_448940_+|WP_005383771.1|DBSCAN-SWA
MTTNQQNAVVSQPQTVVVKLGTSVLTGGTLALDRAHMVELARQCAELKKQGHSIVMVSSGAIAAGREHLGYPALPNEMASKQLLAAVGQSRLIQTWESLFGIYGIKIGQMLLTRADLEDRERFLNARDTINALVANDIVPIVNENDAVATSEIKVGDNDNLSALVGILCGADKLLLLTDQKGLFTADPRKDPNAELIKEVKTIDDTLRKIAGGSGTTLGTGGMATKLQAADIARRAGIEVIIAAGSAPNVIFDSLSAEPQGTRFLPCAEALENRKRWILAGPAASGDIVIDDGAVNAVVGKGSSLLAKGVIKVSGDFARGEVARVTNAHGKLVARGISAYSSDDLTKITGKHSKDIISILGHDYGSEVIHRDDLVVIQE
>NZ_CP014040|447800:454584|452007_452661_+|WP_005383626.1|DBSCAN-SWA
MFTGIVEAVGKLAAITPKGEDITVTVETGTLDMSDVKLGDSIATNGVCLTVVDFGSHYYSADLSLETLKKTGFADYQVGDKVNLEKAMLPTTRLGGHIVSGHVDGVGEIVERNSVGRAIEFWVAMPAEISKYVAEKGSITVDGISLTVNDLRKNAFKLTIVPHTSEETTIDQFQVGRKVNLEVDVLARYMERLLQGQQEDKAESRITMDFLQQNGFA
>NZ_CP014040|447800:454584|454113_454584_+|WP_005381572.1|DBSCAN-SWA
MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVELPLVAQRVAKTGKFDAIVSLGSVIRGGTPHFDYVCSEMNKGLAQVSMEFSIPVAFGVLTVDTIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005383771.1|447800_448940_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.5e-63	42.0
WP_104978847.1|448957_450208_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	6.6e-100	48.7
WP_005381578.1|450414_450864_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_104978849.1|450871_451999_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	7.1e-45	34.2
WP_005383626.1|452007_452661_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-32	37.0
WP_005381573.1|452834_453944_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.2e-65	39.8
WP_005381572.1|454113_454584_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.7e-32	48.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP014040|2578064:2595238|DBSCAN-SWA
CTTATAAGCGCTCTTCTAACCAAGGCTGAACTGTTTTAATTGCCTCTGGTAGTGCGGCTACATCAGTACCACCAGCTTGAGCCATGTCAGGACGACCACCGCCCTTACCACCGACTTGCTCAGCAATCATCTTAACTAGATCACCAGCTTTTACTTTACCAGTTAGATCTTTAGTCACACCAGCAATCAGGCCAACCTTGTCACCTGTTACGTTAGCAAGCAGTACGACACCAGACCCCATTTGGTTCTTAATGTCATCAACCATAGTACGTAGGTTCTTGCTGTCAGCGCCTTCAAGAGCTGCGACTAGAACTTTTGTACCATTGACTTCAACCGCTTTGCCCATGATGTTAGCGCTTTCTGCTGCCGCCATCTTATCTTTTAGCTTCTGCACTTCTTTCTCTAGCGCTTTTGCTTTCTGTGCAGATTCTGCCAGTTTCTCTTCGTACTTCGCGTTTTGAGCTTCAATCGCGTCTAATGCAGCCTCGCCTGTTACCGCCTCAATACGTCGAATACCTGCAGCAATGCCGCTTTCTGAAGTAATTTTGAATAGGCCAATATCACCTGTGCTTGATGCGTGAATACCACCGCAAAGCTCTGTCGAGAAGTCACCCATAGACAGTACGCGTACTTCGTCATCGTACTTCTCACCAAACAGTGCCATTGCGCCTTTCTTCTTAGCAGACTCAATGTCCATCACGTTGGTTTCAATCGTGTGGTTGCGACGAATTTGCGCGTTAACTAGACGCTCAACTTCTTTCAGTTCTGCTGCAGTTACGGCTTCTAGGTGTGAGAAGTCGAAACGTAGGTTGTCTGCCTTCACCAATGAGCCTTTCTGCGTTACGTGCTCACCTAAAACTTGGCGTAGTGCTGCGTGTAGCAAGTGCGTTGCTGAGTGGTTTAGAGAGATAGCTGCGCGGCGCTCTGCGTCAACGATAGTTGCTACTTCATCACCTTTCGCTAGAACGCCTTCTGCCATTACACCGTGGTGCGCGATTGCGTTACCTAGTTTTTGAGTGTCCTCAACGCGGAATACACCAGACTCAGTACGGATTTCACCAGCGTCACCACACTGACCGCCTGACTCTGCGTAGAATGGTGTTTCACCAAGTACGATGATTGCTTTGTCGCCCGCAGATAGAGAATCTACTTCGTTGCCTTCAACGAACATCGCTGCTACAGAACTAGAGCCTTTAGTACCTGTGTAACCACAGAATTCTGTTTGCGTATCAACTTTGATTGCTGCGTTGTAGTCAGTACCAAAATTACCCGCTTCACGCGCACGTTGACGCTGCTCTTCCATCGCTTTCTCAAAACCTTCTTCGTCGATTGCGAACTCACGCTCACGTGCAACGTCGTTAGTTAAGTCAGCTGGGAAGCCGTAAGTATCGTAAAGTTTAAATACGGTTTCGCCGTCCAGTACTTTACCGTCTAGGTTATCTAGTGCTTCGTTTAGAATCGCCATACCGCGCTCAAGTGTACGACCAAAGTTTTCTTCTTCGATACGCAGTACTTTTTCAACCACAGCTTGTTGACGCTTCAGCTCTTCACCAGCCGTACCCATGATGTCAGCTAGAACGCCAACCAACTTGTGGAAGAATGCACCTTGTGCGCCCAGCTTGTTACCGTGACGAACTGCACGACGGATGATACGGCGTAATACGTAACCTCGACCTTCGTTTGAAGGCATAACGCCATCCACGATCAGGAATGAACATGAACGGATGTGGTCAGCGATAACGCGTAGTGATTGGTTTGATAGGTCTTCGTAACCGATCACTTCTGCTGCTGCTTTGATAAGAGCTTGGAATACATCAATCTCGTAGTTTGAGTGAACGCCCTGCATGATTGCAGAGATACGCTCGATACCCATACCAGTATCTACCGATGGTTTTGGTAGCGGTTCCATAGTGCCGTCTGCGTGGCGGTTGAACTGCATGAATACGTTGTTCCAGATCTCGATGAAACGGTCACCATCTTCTTCAGGCGTGCCAGGACGGCCACCCCAGATGTGCTCACCGTGATCGTAGAAGATTTCAGTACATGGACCACAAGGGCCAGTGTCGCCCATTTGCCAGAAGTTATCAGACTCATACGGCTTGCCGCCTTCTTTATCACCAATGCGAACAATACGATCAGCGGGCACGCCAACTTTCTTGTTCCAGATGTCAAACGCTTCGTCATCGGTTTCGTAAACAGTTACCAATAAACGATCCGCTGGCAGTTTAAGAACTTCGGTTAGGAATTCCCAAGCAAAGGAGATCGCATCTTCTTTGAAGTAATCGCCAAAGCTGAAGTTGCCTAACATTTCAAAGAATGTGTGGTGACGAGCAGTGAAGCCAACATTTTCTAGGTCGTTATGTTTACCACCTGCACGTACGCAACGCTGAGCCGTAGTCGCTCGAGTGTAGGCTCGTTTTTCTAAGCCTAAGAAACAATCTTTAAATTGGTTCATACCTGCGTTTGTGAACAGCAGGGTTGGGTCGTTATGTGGAACTAACGATGAACTTTCTACGATTTGGTGTCCTTTGCTCTCAAAGAACTTGAGGAACGCGTTACGAACCTCATCAGTGCTCATGTACATGCAGCTCTTCCTGAAAATAGTCGAGTTAGAATTTTGCCGTATTGTAGATCATGCAAACAGCTGAGACTAGTTTTCTTGAGGAAAAGAGGGAGTAGGAGAAAAAATTTGAAGCAAAACAAAAATCAGTGCGGACGACTGACCGTTAATCTTCGTCCTCAAAGTTCAGCGCGTAGCTGATTTGGTCAAAACTGTAGCCACGATATTGCAGAAATCGCACCTGTTTAGCGTACTCTTTCTGGTCTTTGGCTTTAATACCTTTGAATTTCTTTTCTGCCGCCTGTTTAGCCAGTTCAAACCAATCTTGCGGCTCTTCAGCCATAGCTTGCTCAATCACCGATTCCGCAACACGCTTCTGGTTTAACTCTTGACGAATTCGACGCTCTCCATGTCCTTTGTATACATGCTGTCTAATTTGACTCTTCGCGTAACGTAAATCATCTAGATAATTATGGTCTAGGCAAAAATTAATTGCGATGTCGATGTCTGATTCTTCATAGCCCTTCATCGATAATTTTTGGTAAAGCTCATACTGACCATGATCGCGACGGCTAAGCAATTGGATAGCAGCCTCTTTGCTCGATAATGTCGGCGCCTGGCGTTTTTGGTACATGATGATCCTAAAAGTATTTTTGCTGTACAGGCTCTCAATGGCCTTTGTGATAATTCGATTTTTGATTTCAATAGATACAACAAAGCCCCGCATTGCAGGGCTTTGTCATTTATTAATCTATGAGAGATTAAAACTCTTCAGCTTGCTCTGGCGCTTCACCAGCTTCAGGCGCTTCCGCAAGTGCTGGCGCTAGCAACATTTCACGCAGTTTTGTATCGATAGTTTTAGCCACTTCAGGGTGCTCACGCAGGTAGTTACACGCATTCGCTTTACCTTGACCAATCTTATCGCCATTGTAGCTATACCAAGCACCGGCTTTTTCAACTAACTTGTGCTTCACACCTAGATCGACAAGTTCACCTTCGCGGTTAAAGCCTTGGCCGTACATGATTTGTGTGTTTGCTTCTTTAAATGGTGCTGCAATCTTATTCTTAACAACTTTGATGCGCGTTTCGTTACCTACGACTTCGTCACCTTCTTTGATTGCGCCAGTACGACGGATATCTAGACGAACAGAAGCGTAGAACTTAAGTGCGTTACCACCTGTTGTTGTTTCTGGGTTACCAAACATCACACCAATCTTCATACGGATTTGGTTGATGAAGATACACATACAGTTAGACTGCTTTAGGTTACCCGTTAGCTTACGCATTGCTTGAGAAAGCATACGTGCTTGCAGACCCATGTGGCTATCGCCCATTTCGCCTTCGATTTCTGCTTTCGGTGTTAGCGCTGCAACAGAGTCGACAACCATAACATCGATAGCACCAGAACGTGCAAGTGCGTCACAGATCTCTAGCGCTTGCTCACCTGTGTCTGGCTGAGAAACTAGCAATGCATCGATATCTACGCCAAGTTTCTTCGCGTATACAGGATCTAGAGCGTGCTCTGCATCGATAAACGCACACGTTTTGCCTTCACGTTGCGCAGCAGCAATAAGCTCAAGCGTTAATGTTGTTTTACCTGAAGATTCTGGGCCGTAGATTTCTACGATACGACCCATTGGTAGACCACCAGCACCCAAAGCGATATCAAGAGAAAGAGAACCCGTTGAGATGGTTTCTACGTCCATTGCGCGGTTATCACCAAGGCGCATGATAGAGCCTTTACCGAATTGCTTTTCAATTTGACCTAGCGCAGCGGCGAGCGCTTTCTGTTTGTTCTCGTCCATTACTTTCTCCGATTTATTCATCTTCTTTGGGCGACGAATAGTAATTCATTTTTCTTAAGCAGAAGAACTGCTCAGCAATGAAAGTTATTATACTGTTGATTCATACAGTGTCCATACCTGTATGAAAAAAATTTGGCTGACCTAAAGTCGTGATTTGCTCTAGCCCTTATCAATGCTGGGCTAAAACAATTTAAGAAATTCTAGAGTAGATGTTGATACAATTGAGTCAGCGCATGCTCGACCGCTTTTTTGCGAACTTCTGCACGGTCACCAGTAAAATGCATGGTTTCGACTTGCTGCCAACTTTGGTTATCAGCAAAAGCAAAGCAGACCATGCCGACTGGTTTCTCTTCACTGCCACCCCCCGGCCCTGCAATACCACTGATGGACACACCGATGGTCGCATTGGAGTTTTTCATTGCACCCTGTACCATTTCAATCACAACTGGCTCACTCACTGCACCATGCGCTTCTAACGTTGAAGCTTGCACACCAAGCATCTCCATTTTCGCTTCATTACTGTAGGTGACAAACGCACGGTCAAGCCACGCTGAACTACCAGCAATGTCAGTAATGGCGGTTGCAACACCACCACCAGTGCATGATTCTGCGGTCGTTAAAAGATGCCCGTGTTTAGCCAATAATGCGCCTAAATCGGCACTCAATTTTGTTGTTTTTTCCATAGCCAAAATGCCCTTTGTCTCTTTTTACTTGATAGGGATTCACGTATCCTAAGCCGCTACGGAAATAAACAAAAGAACTTACCTGTGAAAGCTGAACAAAAACACACTCCGATGATGCAGCAATACCTCAAGCTAAAAGCTGAGAACCCAGAGATTTTGCTGTTCTACCGCATGGGCGATTTCTACGAACTCTTTTACGATGATGCCAAGCGAGCTTCTCAGCTTCTTGATATTTCATTGACCAAACGTGGTGCGTCTGCAGGTGAACCTATCCCAATGGCGGGTGTGCCATTTCACGCCGTAGAGGGCTACCTGGCAAAACTTGTTCAGCTTGGTGAGTCTGTGGCGATCTGTGAACAGATTGGCGATCCGGCCACCAGCAAGGGCCCAGTAGAACGTAAAGTTGTGCGTATCGTTACACCAGGTACTGTGACGGATGAGGCGCTGCTTTCTGAGCGTGTCGATAACTTAATCGCAGCAATTTACCATCACAACGGTAAGTTCGGTTATGCGACGCTGGATGTCACCTCTGGTCGCTTCCAACTGACAGAACCAGAAACTGAAGAAGCGATGACAGCCGAGCTTCAACGTACCGCACCACGTGAGCTACTGTTCCCAGAAGATTTTGAACCTGTACATTTAATGGCGAGCCGCAATGGTAACCGTCGTCGCCCAGTCTGGGAGTTTGAGCTTGATACGGCTAAGCAACAACTCAATCAACAATTTGGCACAAAAGATCTGGTTGGTTTTGGTGTAGAACATGCGTCCTTAGGGTTATGTGCTGCTGGTTGTTTGATCCAGTACGTAAAAGATACTCAACGTACGGCTTTACCTCATATTCGCTCTTTAACGTTTGATCATCAGGATCAATCCGTCATCCTTGATGCTGCTACCCGACGTAATCTGGAAATTACTCAAAATCTAGCAGGCGGAACCGATAACACGCTCGCTGCAGTACTCGACCATTGTGCAACTCCGATGGGCAGCCGAATGCTGAAGCGTTGGTTGCATCAGCCTATGCGTTGCATTGAAACGTTAAACAATCGCCTTGATGCGATTGGTGAGATTAAAGAACAAGCTCTGTTTGCTGATCTTCAACCAACGTTAAAGCAAATTGGTGATATTGAACGTATCTTAGCGCGCCTTGCATTACGCTCTGCTCGCCCTCGCGATATGGCTAGACTTCGCAATGCCATGCAACAGCTACCAGAGCTAGAATCTGTCACCGCTTCTTTGACCCATCCGTACCTAACGAAATTGGCGAAGTATGCAGCTCCGATTGACGAAGTATGTGACCTGTTAGAGCGCGCGATTAAAGAAAATCCGCCGGTTGTTATTCGTGATGGTGGCGTCATCGCTGAAGGCTACAATGCGGAGCTCGATGAATGGCGAAAATTGGCAGACGGTGCAACAGAATATCTTGAGCAGCTTGAGCGAGATGAGCGTGAACGACACGGTATCGATACGCTTAAAGTAGGCTATAACAACGTTCATGGCTTCTTTATCCAAGTGAGCCGTGGCCAGAGCCATTTGGTTCCACCGCATTATGTACGTCGCCAAACACTCAAAAACGCTGAACGCTACATCATCCCAGAGCTTAAGGAACACGAAGACAAAGTACTTAACTCGAAATCTAAAGCGTTAGCACTTGAGAAACAGTTGTGGGAAGAACTGTTTGATCTATTGATGCCAAACCTTGAGAAGCTGCAAAACCTAGCTTCTGCTCTGTCTCAACTGGATGTATTACAAAACCTAGCAGAGCGTGCAGATTCGTTAGATTACTGCCGCCCAACGCTTGTGAAAGACGCAGGAATTCACATTCAAGCTGGTCGTCATCCAGTCGTAGAACAAGTAACAACAGAGCCGTTCATCGCGAACCCAATTGAGCTGAACCCAGCCCGTAAGATGTTGATCATTACCGGTCCAAACATGGGTGGTAAATCAACCTACATGCGTCAAACTGCGCTGATTGCATTGATGGCACATATCGGCTCTTATGTACCGGCAGAATCCGCACAGATTGGTTCTTTAGATCGTATATTTACTCGTATTGGTGCGTCAGATGATCTTGCATCTGGCCGCTCGACCTTCATGGTAGAAATGACCGAAACAGCCAATATTCTTCACAACGCAACTAAGAATAGTTTGGTGCTAATGGATGAAATCGGACGCGGTACTAGTACTTACGACGGTCTGTCTTTAGCTTGGGCAAGTGCGGAATGGCTCGCAACACAAATTGGTGCGATGACCCTATTTGCAACCCACTACTTCGAATTAACAGAGTTACCAAGCCAGCTGCCAAACTTAGCGAACGTTCACTTGGATGCCGTAGAACATGGAGATAGCATTGCCTTTATGCACGCAGTTCAAGAAGGTGCGGCAAGTAAGTCTTACGGTCTGGCTGTTGCGGGCTTAGCAGGCGTACCAAAAACGGTCATCAAAAATGCGCGTAACAAGCTATCTCAGCTAGAGCTACTGGGGCAAAACAGTGACACACCACGTCCAAGTGCAGTAGATGTGGCTAACCAGTTGAGCCTGATTCCAGAGCCTAGCGAGGTCGAACAAGCTCTGTCAGGTATTGACCCTGACGACTTAACGCCACGCCAAGCTCTTGAAGAGCTGTATCGCTTGAAGAAGATGCTGTAAACAGACTCACACCGACGAGCAAAAAAGAAAAAAGGCTATGGGGAACCATAGCCTTTTGTGTATCTAGTGAAATACGGATTATTTAATCGTCTTCTACGTTAAACAAGTTTTCCATATTCAAACCTTGTTTGATTAGGACTTCACGAAGACGACGTAAACCTTCCACTTGTATTTGACGTACTCGCTCACGTGTCAGACCAATCTCTCGACCAACTTCTTCCAGCGTCGAAGGCTCATAGCCTAGTAGGCCGAAGCGTCGTGCAAGCACTTCTTTCTGTTTCGGATTCAACTCTTCTAACCAATGAATCAACGATGATTTGATGTCGTCATCTTGAGTCGAAACTTCTGGATCAGAGTTGTTTGCATCAGGAATAATATCCAGCAGCGCTTTCTCACCGTCACCACCGATTGGCGTGTCGACAGAGCTAATACGCTCATTAAGGCGTAACATTTTGCTTACGTCTTCGACTGGAATATCTAATTGAGCAGCAATTTCTTCTGCGGTCGGTTCGTGATCGAGCTTTTGAGAAAGTTCACGCGCAGTACGCAGATAAATGTTCAGCTCTTTCACTACATGGATAGGTAGACGGATCGTGCGAGTTTGGTTCATCAACGCTCGCTCTATCGTTTGTCGGATCCACCACGTTGCGTAAGTAGAGAAACGGAAACCACGTTCTGGGTCGAATTTTTCGACCGCTCGGATCAAGCCGAGGTTACCTTCTTCAATCAGATCAAGTAGTGCTAGACCACGGTTACTGTATCGACGAGAAATCTTAACAACCAAACGTAGGTTACTTTCGATCATACGTTTGCGTGCCGCTTCGTCGCCACGTAGGGCGCGTCTTGCGTAAAGCACTTCTTCTTCGGCAGTAAGTAAAGGTGAGAAGCCAATTTCGCCCAAATACAACTGAGTTGCATCTAAGCTTTTACTGCTCGCGTCAAATTCTTCACGCGCAGTCGCTTTGCTTTCTGTGGATGATGATCTTTCGAGTTCGTTATCAATGGTCTTCACTGACGCATTGTCAAATGCAAACTCTTCAACTTTGGTTACTGTGTTGCTGATACTCATAACGCCTCCCCCTGGCGAGTTAGCAAGACATGACAACTCAATATGTCGCTAAATGATGTCGCAAGTTGTTTTTCAAAGTTTTAAGGCAAATAGCGTTTTGGATTCACTGATTTACCTTGATAGCGAATTTCAAAGTGTAGTTTGACCGACTTTGCACCTGAACTACCCATGGTGGCGATTTTTTGTCCGCTTTTTACGCTTTGTCCTTCTGTGACCAGCAGTTTGTCATTATGTGCGTATGCGCTTAAATAATTGTCGTTATGCTTTACTATAATTAAGTTGCCATAACCTCGTAGCGCATTGCCTGAATAAACGACTGTGCCGGCTGCGGTTGAAACGATAGGTTGACCACGCTGTCCTGCGATGTCGATACCTTTATTTCCCTGTTCTCCCGCCGAAAAGTTCTTGATTACTCTCCCTTTTGTTGGCCACAACCACTTTGAGACTTTATCACTCTTTGCTGTGGTAGTTGGCGCTTTTTGCTTCACTTTTTGGTTATCTTTTGAACCAACATACTCCTTTGTTTTCGATTGTTCAACCTTCTTTGGAGGCTGTTTTTGTACGACTTTAGGCTTAGTCTCTGTAGGTTTTTGACTAGAGTTTTTACTCGAAGGTTTAGGTTTAGAGGCTGTTGATGTTTTCGTCACTGGAGCTGGGGGTGTCGTAACAACAGGAGCCACAACGGGTTCAACTTTTTGACCATATTTAGGGGCGACATATTTCGGAGCCCAAAGTTTTAGCCTCTGTCCTGGGTAGATAGTGTAAGGCTGAGTTAACTCATTGTAACGAACAAGATCATTTACATCTTTATCTGTGACATAAGCTATGAAGTAAAGTGTATCGCCTTTTTTTACCTCATAATAACTCCCTCTGTAACTCCCTCTTTCAAGGCTTGAATAGTCTTTTTTTAGGCTAGAGACAGGTGCAGGGGAATGCGCTGCACAACCAACTAGTCCTGCAGCAAACACAAAGCTAATACCAATATGACGTAGTAACTTATTCACCTATCCCTAACCCTTAAGCTAAATCACCCGCAACCAGAGGTACGAACCGAACCATTTCTACAACGGTAGAGAGATATTCGTCTCCCTTACGCTCTATTTTTAATAACTGTTGTTCCGTATCTCCAACAGGAATGACCATTTTGCCGCCATCTCTTAATTGTGAGAGAAGAGCTTGGGGAATCACTTCAGCGGCAGCGGTAACAATAATAGCATCGAAAGGACCTCTCGCTTCCCAGCCCTGCCACCCATCAGCATGCTTAGTTGAAACATTGTAAATATCCAATTGCTTCAGGCGACGCTTTGCTTCCCATTGCAACGATTTAATTCGCTCAACGGAGTATACATGATCAACAATTTGCGCCAGTACCGCAGTTTGATAACCCGATCCCGTTCCGATTTCCAGAACACGACTCGCCGGTTCTAGCTCAAGCAACTCGGTCATACGAGCAACGATATAAGGCTGAGAAATAGTTTGTCCCTGACCAATTGGTAACGCATTGTTATCATAGGCTTGGTGCATCATCGCTTGAGAAACAAAGCTTTCTCGTGGCAAGCGTTGGATAGCATCCAGAACTCTTTGGTCTTTGATGCCACTGGAGATAAGAAACGCTATCAACCTGTCAGCATGTGGGTTACTCATTACTTCTCTTCCTTTAACCAACTATCCATAGCACGCAGCGACTCGTGAGCGGTGAGATCAACTTGCAGAGGCGTCATTGAAACTCGGCCATGCTCAATTGCATAAAAGTCCGTGCCCTCTCCTGCATCTTGCTCCTTTCCTGGTGGCCCTAACCAATAAATGTCATGGCCTCTCGGATCTTTCTGCTTGATCATATTCTCTGCGTGATGACGTGCACCTAAACGCGTAACTTCAATTTCACCTAAATTCTCTGATGGTAAGTCAGGCACGTTTACGTTCAGTAGACGATTCGTTGGAATCGGCGACGCTAAATGCTGTTGTACAATTTGACGTGCAATTTTAGCGGCGGATTCGAAATGTCGCTTACCCACTAGAGAAAAAGCCACCGACTGAACGCCAAGGAAATGACCTTCCATGGCTGCTGCTACTGTTCCAGAATAAAGAACATCATCACCCAAATTAGCGCCATGGTTGATTCCTGACAGAACAAGATCAGGCAAATCATCTTTCATTAGCTCATTCAGCGCGAAATGCACACAATCCGTGGGCGTGCCTTGCACTGAGTAGATATTTGGGGCAATTTCAGTCACGCGTAATGGTTGTTCTAATGTGAGTGAATTCGAAGCACCTGAACGATTTCGATCAGGTGCGACAATGGTCACTTCAGCGATATCTCTCAACTCATCAGCGAGGGCATGAATCCCTTGAGCATGAACACCATCATCATTGCTGATTAAGACCCTTAAGGGCTTCGGGTTTCGTGAATCCTGTTCCATTAGTATTCTCTTTCTACTTCAACCTCATTAACTAACTCACGAACAATAGAGGTCGCAAAAGATCCCGCATCCAGTGAGAAAGTCAGCGTAATGTTGTTACCTTCAACCGTCCAAGCTAAATCTTTTGGCTTCAGCGCAATATCGCGACGGTCGTGGCGCATGCGATTACCACGAATCAGCGCCATGAGGTCAGGCTCTTCGTCTAAAAACGGTTGCTCTAATGCCAGAGCCTCGGCTTGAGTAGGCAGTGCATTATCGCCAGCAAGCGCAGCGGTAATTGCCGCTTCACCTCGCGCAAATTGCACTTGCAGAGCAGCTATGTTGTTTGCATCAATCAACTGAGTGCCAGAATTCGTCTGTGCAATGTCACCATCAATGAACTTATCAAACACACCATTCTCTAGACGAGCTGAAACGATGCGGTTGAAAATCCACGAACGAGCCGCTGATAAATACATGCTGCGCTTGTTTTGATTGCGGGTACGAACGTTTTCGCGTCCCCATCGACGTCCTTCTTCAAGGTTGTTACCATCGTTACCAAAACGCTGACTACCAAAGTAGTTTGGCACGCCAACTTGTTTCACTTTTTCAAGACGTTGCTCTACATCCGCTATATCTGTCACTTCAGACAAAGTAACCACGAACTCGTTCCCTACTAGGTCACCAGGACGCAGTTTTTTATTGTGACGATCTGTTGCAAGGATTTCGATACTTGGGTATTGAGCTAAAAACGCTGAAAAATCTGGCGTTTCACCTTTCGGTAAATGGACACTTAACCACTGTTCCGTCACCGCATGACGGTCTTTAAGACCCGCCCAGCTAACGTCTTTCGACTTAACACCACAGGCTTTTGCTAACTCGTTAGCAACGAAGCTGGTGTTCTCGCCCGTTTTACGGATACGAACCATTAAGTGCTCGCCTTCGCCCGTAAAGGCAAAACCTAAATCTTCGCGAACCTGAAAATGCTCTGGCTGCGCTTTGATTTTTGCCGATGCAATTGGCTTACCTGTTAGGTAAGCCAATGAAGATAAAATGTCTGACATGATGTGTTTCCGCTGATATCACAGCTTAGAGGAGCAAATTGCTAGTTATTGCTTAAACAGAAGTACAACGGCTTCCGTTGCAATGCCTTCTTTGCGTCCAGTAAAACCGAGACGTTCTGTCGTCGTCGCTTTTACGTTAATGTTACTAATGTCGGTTTCTAGGTCTTCGGCAATCGCCGCACACATTGCGTCAATGTGTGGTGCCATTTTAGGCGCTTGTGCCATGATGGTTACATCAGCATTGCCTAGACGGTAACCTTGCTCTTTGACTCGACGGTAAACGTCTTTCAGTAATTCACGACTGTTTGCGCCTTTCCATTTATCATCCGTATCTGGGAAATGACGACCAATATCGCCGGCAGCAATCGCGCCCAGCAGAGCATCCGTTAACGCATGCAACGCTACATCGCCATCTGAGTGTGCAATCAAACCTTGCTCATAAGGGATTGCTACACCACCAATAATGACCGGGCCTTCACCACCGAATTTATGTACATCGAAACCATGACCAATTCGAATCATTTTCTATCCTTTCTTTATTCGCCGCGCTCACGGCTTAGATAAAACTCGGCTAACGCAAGATCTTCTGGCTGAGTGATTTTTATATTGTTCGCATTCCCTTGAACTAAGGCTGGCTTCTCGCCTAACCATTCCAAAGCCGAGGCTTCATCGGTAATGGTTACACCCTGTTCTAATGCGTCAGCCAGTGCTTGAGTAAGCTGCTGAGTTTTAAACATTTGTGGAGTCAGTGCATGCCACAATGCTTCTCTATCTACCGTATGATCGATATCTTGTACTGCGTTTGCTCGCTTCATTGTATCTCTCACAGGAGATGCGAGAATGCCACCCGTTGAGTGGGCGCAGCAAACATCAATCAAACGGTCAATGTCGGATGTTAATACACATGGCCTCGCAGCGTCGTGGACTAATACCCACTCGCTTTCCAGATGCTCATTGACATAGTTTAGCCCTGATAACACAGAGTCTGCTCTTTCTTTACCACCAGCTACACGAATCACATCTGGGTGCTTAGCAATGGACAATTCTGGGTAATATGGGTCGCCGTCAGTAACGGCAACGACAACCTTAGAAATATTTGGGTGAGAAAGCAGTTTCTCTACGGTATGTTCCAGTACCGCTTTACCTTCGATCAATAAATATTGCTTAGGGCGATCTGCCTTCATTCTGCTCCCTACACCAGCAGCAGGCACAATTGCGATATGCGATGAGTTCATATCCAACATTTTAATGGTTTTCCTCACCTATAATGCGGTAAAAAGTCTCGCCATCTTTAACTAAACCGAGCTCATGACGCGCACGTTCTTCAATCGCATCAAGACCTTGCCTTAAGTCATCAATCTCAGCGAACATTTCATTGTTGCGAGCTTGTAGCTTGCTGTTCACTTGTTGCTGAACTTCAATTTCATCTTTTACTGTGTAGTAGTCAGACACTCCGTTTTTACCAAACCATAGAGTGTATTGAAGCAAGCCAAACAGTAGCGTAAGGGCTATAACAAAGATTCGCATATCGCTGCTAACATTCTGTACCGGAAGGAATTAGATAAGGTGACATATATAGCATAAATGCGAGGTTGCCTCTAGGGGAGAAAGGGAGACTCACACGCTCCTTACAAGAAATAAGCAGCAAAATGAAACAAGCTCATAGGAAGCGCTCCTTACCCATGACCAAAGTAAGAGCCAAAAATACAAACCTATAAATACAAAAAACCGCCGTAGCGATGGTTTCAAAAAGCTATTTAGCGAAACTTTACTCAATAAGAATTAAGCTTGATCTTTAACTTCTTTGAGACCGCTTACTTGAAACATGGAGGAGTGCGCTCACTTAGCGCTTCCGTTATATAAAAAAACACCCCGCCAAAGCAGGGTGTTTTAAAAGCTTTAAGTTAAGCTGCTAATTCAGTGAAGAATTAAGCTTGACCTTTAACTTCTTTAAGACCGTTGAAAGGAGCGCGCTCACCTAGAGCTTCCTCGATACGGATTAGCTGGTTGTACTTAGCAACACGGTCAGAACGGCTCATAGAACCAGTTTTGATTTGACCTGCAGCTGTACCTACCGCTAGGTCAGCGATAGTTGCATCTTCAGTTTCGCCAGAACGGTGAGAGATTACTGCTGTGTAACCTGCGTCTTTAGCCATCTTGATTGCAGCTAGAGTCTCAGTTAGAGAACCGATTTGGTTGAACTTGATAAGGATAGAGTTAGCTACGCCTTTCTCGATACCTTCAGCAAGGATCTTAGTGTTAGTAACGAATAGATCGTCACCTACTAGTTGAAGCTTGTCACCTAGTAGTTCAGTTTGGTGCTTGAAGCCATCCCAGTCAGACTCGTCTAGACCGTCTTCGATAGAAACGATTGGGAATTGGTTAGCTAGCTCAGCTAGGTAGTGGTTGAACTCTTCAGAAGTGAAAGTTTTACCTTCGCCTTTCATGTTGTAGATGCCAGCTTCTTTGTCGAAGAACTCAGATGCAGCACAGTCCATAGCTAGAGTAACGTCTTTACCTAGTTCATAACCAGCAGCTGCAACAGCTTCTGCGATAACTTCTAGAGCTTCAGCGTTAGATTTAAGGTTAGGAGCGAAACCACCTTCATCACCAACTGCAGTGCTGTAGCCTTTAGACTTAAGAACTTTAGCTAGGTTGTGGAATACTTCTGCACCGATACGTAGACCTTCTTTAAGAGTCTTAGCGCCAACTGGTTGGATCATGAACTCTTGGATGTCAACGTTGTTGTCTGCGTGCTCGCCACCGTTGATGATGTTCATCATTGGTAGAGGCATAGAGAACTGACCTGCAGTGCCGTTTAGCTCAGCGATGTGCTCGTATAGAGGCATGCCTTTCGCAGCAGCAGCAGCTTTAGCGTTTGCTAGAGAAACAGCTAGGATAGCGTTAGCACCGAATTTAGATTTGTTTTCAGTGCCGTCTAGTTCGATCATTACTGCGTCGATTGCAGCTTGGTCTTTAGCGTCTTTGCCAACTAGAGCTTCAGCGATTGGGCCGTTTACAGCTTCAACTGCTTTAAGAACACCTTTACCTAGGAAACGTGCTTTGTCACCGTCACGTAGCTCAAGAGCTTCGCGAGAACCAGTAGATGCGCCAGATGGAGCTGCCGCCATACCTACGAAACCGCCTTCTAGGTGTACTTCAGCTTCTACAGTTGGGTTACCACGTGAGTCGATGATTTCACGACCTAGAACTTTAACGATCTTAGACATTAATGTTTCCTCTCGTTTCAAATATAAATGTCAATCTTAAAGGGCAGCAGCACAACCTTCGCCGCCGCCCGTATCCTTTTACTTCTCGAATTCGCCGCGTGCGTTTTGGCCCGCAGCCTTAACAAAACCTGCAAACAATGGATGTCCATCGCGAGGAGTCGAGGTGAATTCTGGGTGGAACTGAGCCGCTACAAACCATGGGTGAGCTGGGTTCTCAATCATTTCCACTAACTTCTTGTCCGCAGATAGACCTGATACTTTTAGACCTGCTTTTTCGATTTGCGGACGAAGCACGTTATTCACTTCGTAACGGTGACGGTGACGTTCATGGATCGTCGCGCTACCGTACAGTTCACGAGCTTTAGTCCCTTTCTCTAGGTGACACAACTGTGAACCAAGACGCATCGTACCGCCTAGGTCAGACTTTTCAGTACGCTCTTCTACGCTACCTGATTCGTCTACCCACTCTGTGATCAAACCTACCACAGGGTACTTAGTCTCTTTGTTAAATTCTGTTGAATGTGCACCTTCCATACCCGCAACGTTACGCGCGTATTCGATTAGTGCAACTTGCATACCCAAACAAATACCTAGGTAAGGCACGTTATTTTCACGTGCATATTGAGCCGCACGGATCTTGCCTTCAATACCACGATCGCCGAAGCCACCTGGTACTAGGATCGCGTCCAAACCTTCTAGAAGTTCAACGCCTTTTGTTTCGATATCTTGTGAGTCTACATACTTAATTGTGACGCTTAGACGGTTTTTCAAGCCAGCGTGTTTAAGCGCTTCGTTCACAGATTTGTATGCATCTGGTAATTCAATGTATTTACCAACCATACCGATGGTTACTTCACCAGTAGGATTTGCTTCTTCGTAAATAACCTGTTCCCACTCAGAAAGGTCAGCTTCAGGAGCTGTGATGCCAAAGCGAGCACACACAAGGTCATCTAGACCTTGAGATTTAATCAACTGAGGGATCTTGTAGATAGAGTCTACATCCTTCATTGAAATTACTGCTTTTTCTGGAACATTACAGAACAGTGCGATTTTTTTACGCTCATTCGCAGGAATAACGCGATCGCTACGGCAAACTAGGATGTCTGGCTGAATACCGATAGATAGAAGTTCTTTTACAGAGTGTTGCGTCGGCTTAGTTTTCACTTCGCCCGCTGCCGCTAGGTAAGGAACAAGTGTTAGGTGCATGAACATTGCGCGCTCACGGCCTAGCTCAACAGCTAGCTGACGAATCGCTTCCATAAATGGTAGTGATTCGATATCACCAACAGTACCGCCAACTTCAACGATAGCCACATCATGGCCTTCAGAACCTGCAATAACGCGATCTTTGATTGCGTTAGTGATATGAGGGATAACTTGAATAGTTGCGCCTAGGTAGTCACCACGACGTTCTTTACGAAGTACGTCGGCATAAACACGACCTGCAGTGAAGTTGTTACGCTTGGTCATCTTGGTACGGATGAAACGCTCGTAGTGACCAAGGTCAAGGTCAGTCTCTGCGCCATCTTCTGTAACGAACACTTCACCGTGCTGAGTAGGGCTCATTGTGCCCGGGTCAACGTTGATGTAAGGGTCAAGCTTCATCATAGTCACCTTAAGACCACGAGCTTCTAGAATAGCCGCAAGAGATGCTGCTGCAATACCTTTACCTAGAGAGGATACAACCCCGCCAGTAACAAAAATGTAATTTGTCGTCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP014040|2578064:2595238|2590825_2591533_-|WP_017633548.1|DBSCAN-SWA
MLDMNSSHIAIVPAAGVGSRMKADRPKQYLLIEGKAVLEHTVEKLLSHPNISKVVVAVTDGDPYYPELSIAKHPDVIRVAGGKERADSVLSGLNYVNEHLESEWVLVHDAARPCVLTSDIDRLIDVCCAHSTGGILASPVRDTMKRANAVQDIDHTVDREALWHALTPQMFKTQQLTQALADALEQGVTITDEASALEWLGEKPALVQGNANNIKITQPEDLALAEFYLSRERGE
>NZ_CP014040|2578064:2595238|2583195_2585757_+|WP_104979687.1|DBSCAN-SWA
MKAEQKHTPMMQQYLKLKAENPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGVPFHAVEGYLAKLVQLGESVAICEQIGDPATSKGPVERKVVRIVTPGTVTDEALLSERVDNLIAAIYHHNGKFGYATLDVTSGRFQLTEPETEEAMTAELQRTAPRELLFPEDFEPVHLMASRNGNRRRPVWEFELDTAKQQLNQQFGTKDLVGFGVEHASLGLCAAGCLIQYVKDTQRTALPHIRSLTFDHQDQSVILDAATRRNLEITQNLAGGTDNTLAAVLDHCATPMGSRMLKRWLHQPMRCIETLNNRLDAIGEIKEQALFADLQPTLKQIGDIERILARLALRSARPRDMARLRNAMQQLPELESVTASLTHPYLTKLAKYAAPIDEVCDLLERAIKENPPVVIRDGGVIAEGYNAELDEWRKLADGATEYLEQLERDERERHGIDTLKVGYNNVHGFFIQVSRGQSHLVPPHYVRRQTLKNAERYIIPELKEHEDKVLNSKSKALALEKQLWEELFDLLMPNLEKLQNLASALSQLDVLQNLAERADSLDYCRPTLVKDAGIHIQAGRHPVVEQVTTEPFIANPIELNPARKMLIITGPNMGGKSTYMRQTALIALMAHIGSYVPAESAQIGSLDRIFTRIGASDDLASGRSTFMVEMTETANILHNATKNSLVLMDEIGRGTSTYDGLSLAWASAEWLATQIGAMTLFATHYFELTELPSQLPNLANVHLDAVEHGDSIAFMHAVQEGAASKSYGLAVAGLAGVPKTVIKNARNKLSQLELLGQNSDTPRPSAVDVANQLSLIPEPSEVEQALSGIDPDDLTPRQALEELYRLKKML
>NZ_CP014040|2578064:2595238|2582628_2583111_-|WP_005380875.1|DBSCAN-SWA
MEKTTKLSADLGALLAKHGHLLTTAESCTGGGVATAITDIAGSSAWLDRAFVTYSNEAKMEMLGVQASTLEAHGAVSEPVVIEMVQGAMKNSNATIGVSISGIAGPGGGSEEKPVGMVCFAFADNQSWQQVETMHFTGDRAEVRKKAVEHALTQLYQHLL
>NZ_CP014040|2578064:2595238|2578064_2580647_-|WP_005380872.1|tRNA|DBSCAN-SWA
MYMSTDEVRNAFLKFFESKGHQIVESSSLVPHNDPTLLFTNAGMNQFKDCFLGLEKRAYTRATTAQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKEDAISFAWEFLTEVLKLPADRLLVTVYETDDEAFDIWNKKVGVPADRIVRIGDKEGGKPYESDNFWQMGDTGPCGPCTEIFYDHGEHIWGGRPGTPEEDGDRFIEIWNNVFMQFNRHADGTMEPLPKPSVDTGMGIERISAIMQGVHSNYEIDVFQALIKAAAEVIGYEDLSNQSLRVIADHIRSCSFLIVDGVMPSNEGRGYVLRRIIRRAVRHGNKLGAQGAFFHKLVGVLADIMGTAGEELKRQQAVVEKVLRIEEENFGRTLERGMAILNEALDNLDGKVLDGETVFKLYDTYGFPADLTNDVAREREFAIDEEGFEKAMEEQRQRAREAGNFGTDYNAAIKVDTQTEFCGYTGTKGSSSVAAMFVEGNEVDSLSAGDKAIIVLGETPFYAESGGQCGDAGEIRTESGVFRVEDTQKLGNAIAHHGVMAEGVLAKGDEVATIVDAERRAAISLNHSATHLLHAALRQVLGEHVTQKGSLVKADNLRFDFSHLEAVTAAELKEVERLVNAQIRRNHTIETNVMDIESAKKKGAMALFGEKYDDEVRVLSMGDFSTELCGGIHASSTGDIGLFKITSESGIAAGIRRIEAVTGEAALDAIEAQNAKYEEKLAESAQKAKALEKEVQKLKDKMAAAESANIMGKAVEVNGTKVLVAALEGADSKNLRTMVDDIKNQMGSGVVLLANVTGDKVGLIAGVTKDLTGKVKAGDLVKMIAEQVGGKGGGRPDMAQAGGTDVAALPEAIKTVQPWLEERL
>NZ_CP014040|2578064:2595238|2580789_2581257_-|WP_005383799.1|DBSCAN-SWA
MYQKRQAPTLSSKEAAIQLLSRRDHGQYELYQKLSMKGYEESDIDIAINFCLDHNYLDDLRYAKSQIRQHVYKGHGERRIRQELNQKRVAESVIEQAMAEEPQDWFELAKQAAEKKFKGIKAKDQKEYAKQVRFLQYRGYSFDQISYALNFEDED
>NZ_CP014040|2578064:2595238|2591534_2591816_-|WP_005380907.1|DBSCAN-SWA
MRIFVIALTLLFGLLQYTLWFGKNGVSDYYTVKDEIEVQQQVNSKLQARNNEMFAEIDDLRQGLDAIEERARHELGLVKDGETFYRIIGEENH
>NZ_CP014040|2578064:2595238|2590334_2590811_-|WP_005380896.1|DBSCAN-SWA
MIRIGHGFDVHKFGGEGPVIIGGVAIPYEQGLIAHSDGDVALHALTDALLGAIAAGDIGRHFPDTDDKWKGANSRELLKDVYRRVKEQGYRLGNADVTIMAQAPKMAPHIDAMCAAIAEDLETDISNINVKATTTERLGFTGRKEGIATEAVVLLFKQ
>NZ_CP014040|2578064:2595238|2585839_2586826_-|WP_005380887.1|DBSCAN-SWA
MSISNTVTKVEEFAFDNASVKTIDNELERSSSTESKATAREEFDASSKSLDATQLYLGEIGFSPLLTAEEEVLYARRALRGDEAARKRMIESNLRLVVKISRRYSNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERALMNQTRTIRLPIHVVKELNIYLRTARELSQKLDHEPTAEEIAAQLDIPVEDVSKMLRLNERISSVDTPIGGDGEKALLDIIPDANNSDPEVSTQDDDIKSSLIHWLEELNPKQKEVLARRFGLLGYEPSTLEEVGREIGLTRERVRQIQVEGLRRLREVLIKQGLNMENLFNVEDD
>NZ_CP014040|2578064:2595238|2587843_2588470_-|WP_005380892.1|DBSCAN-SWA
MSNPHADRLIAFLISSGIKDQRVLDAIQRLPRESFVSQAMMHQAYDNNALPIGQGQTISQPYIVARMTELLELEPASRVLEIGTGSGYQTAVLAQIVDHVYSVERIKSLQWEAKRRLKQLDIYNVSTKHADGWQGWEARGPFDAIIVTAAAEVIPQALLSQLRDGGKMVIPVGDTEQQLLKIERKGDEYLSTVVEMVRFVPLVAGDLA
>NZ_CP014040|2578064:2595238|2588469_2589246_-|WP_005380894.1|DBSCAN-SWA
MEQDSRNPKPLRVLISNDDGVHAQGIHALADELRDIAEVTIVAPDRNRSGASNSLTLEQPLRVTEIAPNIYSVQGTPTDCVHFALNELMKDDLPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQSVAFSLVGKRHFESAAKIARQIVQQHLASPIPTNRLLNVNVPDLPSENLGEIEVTRLGARHHAENMIKQKDPRGHDIYWLGPPGKEQDAGEGTDFYAIEHGRVSMTPLQVDLTAHESLRAMDSWLKEEK
>NZ_CP014040|2578064:2595238|2592217_2593519_-|WP_005383785.1|DBSCAN-SWA
MSKIVKVLGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKARFLGKGVLKAVEAVNGPIAEALVGKDAKDQAAIDAVMIELDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTAGQFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTLAMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAELANQFPIVSIEDGLDESDWDGFKHQTELLGDKLQLVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGERAPFNGLKEVKGQA
>NZ_CP014040|2578064:2595238|2593597_2595238_-|WP_021034029.1|DBSCAN-SWA
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLKVTMMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTKRNNFTAGRVYADVLRKERRGDYLGATIQVIPHITNAIKDRVIAGSEGHDVAIVEVGGTVGDIESLPFMEAIRQLAVELGRERAMFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILVCRSDRVIPANERKKIALFCNVPEKAVISMKDVDSIYKIPQLIKSQGLDDLVCARFGITAPEADLSEWEQVIYEEANPTGEVTIGMVGKYIELPDAYKSVNEALKHAGLKNRLSVTIKYVDSQDIETKGVELLEGLDAILVPGGFGDRGIEGKIRAAQYARENNVPYLGICLGMQVALIEYARNVAGMEGAHSTEFNKETKYPVVGLITEWVDESGSVEERTEKSDLGGTMRLGSQLCHLEKGTKARELYGSATIHERHRHRYEVNNVLRPQIEKAGLKVSGLSADKKLVEMIENPAHPWFVAAQFHPEFTSTPRDGHPLFAGFVKAAGQNARGEFEK
>NZ_CP014040|2578064:2595238|2581384_2582428_-|WP_005380874.1|DBSCAN-SWA
MDENKQKALAAALGQIEKQFGKGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVYAKKLGVDIDALLVSQPDTGEQALEICDALARSGAIDVMVVDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGDEVVGNETRIKVVKNKIAAPFKEANTQIMYGQGFNREGELVDLGVKHKLVEKAGAWYSYNGDKIGQGKANACNYLREHPEVAKTIDTKLREMLLAPALAEAPEAGEAPEQAEEF
>NZ_CP014040|2578064:2595238|2589245_2590289_-|WP_104979689.1|tRNA|DBSCAN-SWA
MSDILSSLAYLTGKPIASAKIKAQPEHFQVREDLGFAFTGEGEHLMVRIRKTGENTSFVANELAKACGVKSKDVSWAGLKDRHAVTEQWLSVHLPKGETPDFSAFLAQYPSIEILATDRHNKKLRPGDLVGNEFVVTLSEVTDIADVEQRLEKVKQVGVPNYFGSQRFGNDGNNLEEGRRWGRENVRTRNQNKRSMYLSAARSWIFNRIVSARLENGVFDKFIDGDIAQTNSGTQLIDANNIAALQVQFARGEAAITAALAGDNALPTQAEALALEQPFLDEEPDLMALIRGNRMRHDRRDIALKPKDLAWTVEGNNITLTFSLDAGSFATSIVRELVNEVEVEREY
>NZ_CP014040|2578064:2595238|2586906_2587830_-|WP_017633546.1|DBSCAN-SWA
MNKLLRHIGISFVFAAGLVGCAAHSPAPVSSLKKDYSSLERGSYRGSYYEVKKGDTLYFIAYVTDKDVNDLVRYNELTQPYTIYPGQRLKLWAPKYVAPKYGQKVEPVVAPVVTTPPAPVTKTSTASKPKPSSKNSSQKPTETKPKVVQKQPPKKVEQSKTKEYVGSKDNQKVKQKAPTTTAKSDKVSKWLWPTKGRVIKNFSAGEQGNKGIDIAGQRGQPIVSTAAGTVVYSGNALRGYGNLIIVKHNDNYLSAYAHNDKLLVTEGQSVKSGQKIATMGSSGAKSVKLHFEIRYQGKSVNPKRYLP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005380872.1|2578064_2580647_-|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	5.9e-79	38.1
WP_005383799.1|2580789_2581257_-	recombination regulator RecX	NA	NA	NA	NA
WP_005380874.1|2581384_2582428_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	8.1e-112	61.0
WP_005380875.1|2582628_2583111_-	nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	8.3e-27	48.1
WP_104979687.1|2583195_2585757_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	7.8e-31	23.5
WP_005380887.1|2585839_2586826_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.9e-36	35.2
WP_017633546.1|2586906_2587830_-	peptidoglycan DD-metalloendopeptidase family protein	D7RWE0	Brochothrix_phage	4.1e-06	35.2
WP_005380892.1|2587843_2588470_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.3e-37	54.5
WP_005380894.1|2588469_2589246_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.3e-66	49.4
WP_104979689.1|2589245_2590289_-|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_005380896.1|2590334_2590811_-	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_017633548.1|2590825_2591533_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	A0A2H4UTB4	Bodo_saltans_virus	7.0e-06	24.3
WP_005380907.1|2591534_2591816_-	cell division protein FtsB	NA	NA	NA	NA
WP_005383785.1|2592217_2593519_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.1e-137	60.6
WP_021034029.1|2593597_2595238_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.1e-154	52.1