CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021256	Legionella pneumophila strain D-4954 chromosome, complete genome	2 crisprs	cas1,cas2,cas4,cas3,DEDDh,DinG,WYL,csa3	0	5	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021256_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021256_1

177103-178910

TypeII

Consensus_repeat	Method
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	PILER-CR
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CRISPRCasFinder
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CRT

25 spacers

cas4,cas2,cas1,cas9

The CRISPR arrays of NZ_CP021256_1

>merge|NZ_CP021256|1|177103-178910|PILER-CR,CRISPRCasFinder,CRT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAACAAAAATAAGAATCATGGTCACGCTCCTAATTGATTCAATAATCCCTCATCTAAAAATCCAACCACTGAAACACTACTGTTTTATTATCGTTGCTCTAATCGCTTTAACAATAATCCCTCATCTAAAAATCCAACCACTGAAACATAAACTATAATTTCCACAACACAATAAACTATCAATAATCCCTCATCTAAAAATCCAACCACTGAAACATGTAAATAAATGATTACGTAACGCCGTTTCAATTCAATAATCCCTCATCTAAAAATCCAACCACTGAAACATGTCTCTGCTTGGAACTGTTCTCTCCCCATTTCAACAATAATCCCTCATCTAAAAATCCAACCACTGAAACTCTGTTCACCCTACACAAAAGCCCGTAGCTTTAATGCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCTTGATGTATGGCGCATACAAGCAGACGACGACACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTTAACACATATTGATAGGCGTCTTTCTCTACGCACAATAATCCCTCATCTAAAAATCCAACCACTGAAACGAAGGTATGATGAGGATATCTGCTTTAGAGTGGTCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCCTGTAATTGCAGGTAAGGCTTTATTGACAGTTAAACAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTTCTATGTTCAGTTTTCCAATTTATTATTGACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCCATAAGCCCCATCAAGATGGAAATTGCCCAGATCAATAATCCCTCATCTAAAAATCCAACCACTGAAACGTAAATACAACATGGTTACTAACTTACCGTGCTACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACACCGTGTCGGAACTTGCCCAAATCACGCCAAAACTCAATAATCCCTCATCTAAAAATCCAACCACTGAAACGTGACATATTAGAAACCATGGCTCCAAAGCTATACAATAATCCCTCATCTAAAAATCCAACCACTGAAACGTTTATTAATGAATAGTTGCATTTTGTGCAGCAAAACAATAATCCCTCATCTAAAAATCCAACCACTGAAACGTTTAAACGGGCTTATTTACACCTAGTTCTGCTCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCGGTATTAAAACCTACATGGAAAGGTATAATGTATCAATAATCCCTCATCTAAAAATCCAACCACTGAAACATCTCATATCCAGCCTCTAAATTTTTTAGTAAAACAATAATCCCTCATCTAAAAATCCAACCACTGAAACCAAGTAAATAACCTCTAAGGTTAATTTTGTATATCAATAATCCCTCATCTAAAAATCCAACCACTGAAACAGAATTAAGCACAAAGTATATAAATTATAAAGACAACAATAATCCCTCATCTAAAAATCCAACCACTGAAACATCCCGAAAATCAAAATTTAGCATTTCCACGCACACAATAATCCCTCATCTAAAAATCCAACCACTGAAACTAATAGGATTATATGTAGGTAATTTACGATAATGAACAATAATCCCTCATCTAAAAATCCAACCACTGAAACTCGAAAGAAATGATTCGAAGCGCAGCGAATGGGGTCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCTGTCGGCATAACTCTGTATATCTCTGTGTAGGCCCAATAATCCCTCATCTAAAAATTTAACTAATGAAAT

>NZ_CP021256|1|1|177103-178552|PILER-CR
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AAAAATAAGAATCATGGTCACGCTCCTAATTGATT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACTACTGTTTTATTATCGTTGCTCTAATCGCTTTAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATAAACTATAATTTCCACAACACAATAAACTAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATGTAAATAAATGATTACGTAACGCCGTTTCAATT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATGTCTCTGCTTGGAACTGTTCTCTCCCCATTTCAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCTGTTCACCCTACACAAAAGCCCGTAGCTTTAATG
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTTGATGTATGGCGCATACAAGCAGACGACGACAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTAACACATATTGATAGGCGTCTTTCTCTACGCA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GAAGGTATGATGAGGATATCTGCTTTAGAGTGGT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCTGTAATTGCAGGTAAGGCTTTATTGACAGTTAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTCTATGTTCAGTTTTCCAATTTATTATTGAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCATAAGCCCCATCAAGATGGAAATTGCCCAGAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTAAATACAACATGGTTACTAACTTACCGTGCTAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACCGTGTCGGAACTTGCCCAAATCACGCCAAAACT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTGACATATTAGAAACCATGGCTCCAAAGCTATA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTTTATTAATGAATAGTTGCATTTTGTGCAGCAAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTTTAAACGGGCTTATTTACACCTAGTTCTGCT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CGGTATTAAAACCTACATGGAAAGGTATAATGTAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATCTCATATCCAGCCTCTAAATTTTTTAGTAAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CAAGTAAATAACCTCTAAGGTTAATTTTGTATAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC

>NZ_CP021256|1|1|177103-178910|CRISPRCasFinder
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AAAAATAAGAATCATGGTCACGCTCCTAATTGATT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACTACTGTTTTATTATCGTTGCTCTAATCGCTTTAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATAAACTATAATTTCCACAACACAATAAACTAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATGTAAATAAATGATTACGTAACGCCGTTTCAATT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATGTCTCTGCTTGGAACTGTTCTCTCCCCATTTCAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCTGTTCACCCTACACAAAAGCCCGTAGCTTTAATG
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTTGATGTATGGCGCATACAAGCAGACGACGACAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTAACACATATTGATAGGCGTCTTTCTCTACGCA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GAAGGTATGATGAGGATATCTGCTTTAGAGTGGT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCTGTAATTGCAGGTAAGGCTTTATTGACAGTTAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTCTATGTTCAGTTTTCCAATTTATTATTGAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCATAAGCCCCATCAAGATGGAAATTGCCCAGAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTAAATACAACATGGTTACTAACTTACCGTGCTAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACCGTGTCGGAACTTGCCCAAATCACGCCAAAACT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTGACATATTAGAAACCATGGCTCCAAAGCTATA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTTTATTAATGAATAGTTGCATTTTGTGCAGCAAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTTTAAACGGGCTTATTTACACCTAGTTCTGCT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CGGTATTAAAACCTACATGGAAAGGTATAATGTAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATCTCATATCCAGCCTCTAAATTTTTTAGTAAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CAAGTAAATAACCTCTAAGGTTAATTTTGTATAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AGAATTAAGCACAAAGTATATAAATTATAAAGACAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATCCCGAAAATCAAAATTTAGCATTTCCACGCACA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TAATAGGATTATATGTAGGTAATTTACGATAATGAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCGAAAGAAATGATTCGAAGCGCAGCGAATGGGGTC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTGTCGGCATAACTCTGTATATCTCTGTGTAGGCC
CAATAATCCCTCATCTAAAAATTTAACTAATGAAAT

>NZ_CP021256|1|1|177103-178910|CRT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AAAAATAAGAATCATGGTCACGCTCCTAATTGATT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACTACTGTTTTATTATCGTTGCTCTAATCGCTTTAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATAAACTATAATTTCCACAACACAATAAACTAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATGTAAATAAATGATTACGTAACGCCGTTTCAATT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATGTCTCTGCTTGGAACTGTTCTCTCCCCATTTCAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCTGTTCACCCTACACAAAAGCCCGTAGCTTTAATG
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTTGATGTATGGCGCATACAAGCAGACGACGACAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTAACACATATTGATAGGCGTCTTTCTCTACGCA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GAAGGTATGATGAGGATATCTGCTTTAGAGTGGT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCTGTAATTGCAGGTAAGGCTTTATTGACAGTTAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTCTATGTTCAGTTTTCCAATTTATTATTGAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCATAAGCCCCATCAAGATGGAAATTGCCCAGAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTAAATACAACATGGTTACTAACTTACCGTGCTAC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACCGTGTCGGAACTTGCCCAAATCACGCCAAAACT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTGACATATTAGAAACCATGGCTCCAAAGCTATA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTTTATTAATGAATAGTTGCATTTTGTGCAGCAAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GTTTAAACGGGCTTATTTACACCTAGTTCTGCT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CGGTATTAAAACCTACATGGAAAGGTATAATGTAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATCTCATATCCAGCCTCTAAATTTTTTAGTAAAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CAAGTAAATAACCTCTAAGGTTAATTTTGTATAT
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AGAATTAAGCACAAAGTATATAAATTATAAAGACAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATCCCGAAAATCAAAATTTAGCATTTCCACGCACA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TAATAGGATTATATGTAGGTAATTTACGATAATGAA
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCGAAAGAAATGATTCGAAGCGCAGCGAATGGGGTC
CAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTGTCGGCATAACTCTGTATATCTCTGTGTAGGCC
CAATAATCCCTCATCTAAAAATTTAACTAATGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021256.1\|WP_027223967.1\|170899_175018_+\|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12	cas9	cd09704_cas9_CAS-II-B	gnl\|CDD\|187835
NZ_CP021256.1\|WP_011212795.1\|176293_176887_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
NZ_CP021256.1\|WP_011212794.1\|176013_176313_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_CP021256.1\|WP_011212799.1\|181736_181940_+\|carbon-storage-regulator	unknown	unknown	gnl\|CDD\|376847
NZ_CP021256.1\|WP_062726620.1\|162518_163511_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NZ_CP021256.1\|WP_062726619.1\|161317_162508_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP021256.1\|WP_106220924.1\|167292_169308_+\|M3-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341051
NZ_CP021256.1\|WP_106220920.1\|159909_161334_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_CP021256.1\|WP_106220922.1\|165858_167196_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021256.1\|WP_021437111.1\|181361_181724_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021256.1\|WP_029346047.1\|184993_185704_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271354
NZ_CP021256.1\|WP_027223966.1\|175014_176007_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
NZ_CP021256.1\|WP_011212801.1\|182248_182530_+\|VirB3-family-type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|368285
NZ_CP021256.1\|WP_187296496.1\|170102_170741_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021256.1\|WP_027223964.1\|180526_181396_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021256.1\|WP_029346046.1\|182516_184997_+\|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase	unknown	unknown	gnl\|CDD\|273346
NZ_CP021256.1\|WP_104411317.1\|181954_182239_+\|TrbC/VirB2-family-protein	unknown	unknown	gnl\|CDD\|368210
NZ_CP021256.1\|WP_080282870.1\|179688_180372_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|119397
NZ_CP021256.1\|WP_011212804.1\|185718_185865_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP021256.1\|WP_050486565.1\|179357_179699_+\|DUF45-domain-containing-protein	unknown	unknown	gnl\|CDD\|307807

Protein	Function_ID	Function_description	E-value
NZ_CP021256.1\|WP_027223967.1\|170899_175018_+\|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12	gnl\|CDD\|187835	cd09704, Csx12, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	0
NZ_CP021256.1\|WP_011212795.1\|176293_176887_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	7.69466e-15
NZ_CP021256.1\|WP_011212794.1\|176013_176313_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.29256e-05
NZ_CP021256.1\|WP_062726620.1\|162518_163511_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	5.34837e-172
NZ_CP021256.1\|WP_062726619.1\|161317_162508_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP021256.1\|WP_106220924.1\|167292_169308_+\|M3-family-metallopeptidase	gnl\|CDD\|341051	cd06456, M3A_DCP, Peptidase family M3, dipeptidyl carboxypeptidase (DCP). Peptidase family M3 dipeptidyl carboxypeptidase (DCP; Dcp II; peptidyl dipeptidase; EC 3.4.15.5). This metal-binding M3A family also includes oligopeptidase A (OpdA; EC 3.4.24.70). DCP cleaves dipeptides off the C-termini of various peptides and proteins, the smallest substrate being N-blocked tripeptides and unblocked tetrapeptides. DCP from Escherichia coli is inhibited by the anti-hypertensive drug captopril, an inhibitor of the mammalian angiotensin converting enzyme (ACE, also called peptidyl dipeptidase A). OpdA may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. It can also cleave N-acetyl-L-Ala. This family also includes Arabidopsis thaliana organellar oligopeptidase OOP (At5g65620), which plays a role in targeting peptide degradation in mitochondria and chloroplasts; it degrades peptide substrates that are between 8 to 23 amino acid residues, and shows a weak preference for hydrophobic residues (F/L) at the P1 position.	0
NZ_CP021256.1\|WP_106220920.1\|159909_161334_-\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_CP021256.1\|WP_029346047.1\|184993_185704_+\|hypothetical-protein	gnl\|CDD\|271354	cd14262, VirB5_like, VirB5 protein family. This family contains VirB5 domains, including TraC, a VirB5 homolog encoded by the pKM101 plasmid, and similar proteins. VirB5 is one of 11 conserved proteins (VirB1-VirB11) in Agrobacterium tumefaciens, the causative agent of crown gall disease, that span the inner and the outer membrane, and is involved in type IV DNA secretion systems (T4SS) which mediate the translocation of virulence factors (proteins and/or DNA) from Gram-negative bacteria into eukaryotic cells. VirB5 assembles extracellular pili by interacting with several essential proteins. VirB2-VirB5 complex formation precedes incorporation into pili; it depends on the inner membrane protein VirB4 to interact directly with and stabilize VirB8 in order for VirB5 to bind to VirB8 and VirB10. Mutagenesis studies show that VirB5 proteins participate in protein-protein interactions important for pilus assembly and function.	3.8699e-17
NZ_CP021256.1\|WP_027223966.1\|175014_176007_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.18578e-80
NZ_CP021256.1\|WP_011212801.1\|182248_182530_+\|VirB3-family-type-IV-secretion-system-protein	gnl\|CDD\|368285	pfam05101, VirB3, Type IV secretory pathway, VirB3-like protein. This family includes the Type IV secretory pathway VirB3 protein, that is found associated with bacterial inner and outer membranes. The family also includes the conjugal transfer protein TrbD family that contains a nucleotide binding motif and may provide energy for the export of DNA or the export of other Trb proteins.	7.62347e-18
NZ_CP021256.1\|WP_011212799.1\|181736_181940_+\|carbon-storage-regulator	gnl\|CDD\|376847	pfam02599, CsrA, Global regulator protein family. This is a family of global regulator proteins. This protein is a RNA-binding protein and a global regulator of carbohydrate metabolism genes facilitating mRNA decay. In E. coli CsrA binds the CsrB RNA molecule to form the Csr regulatory system which has a strong negative regulatory effect on glycogen biosynthesis, glyconeogenesis and glycogen catabolism and a positive regulatory effect on glycolysis. In other bacteria such as Erwinia caratovara RmsA has been shown to regulate the production of virulence determinants, such extracellular enzymes. RmsA binds to RmsB regulatory RNA.	3.39121e-14
NZ_CP021256.1\|WP_029346046.1\|182516_184997_+\|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase	gnl\|CDD\|273346	TIGR00929, CAG_pathogenicity_island_protein_23, type IV secretion/conjugal transfer ATPase, VirB4 family. Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).	0
NZ_CP021256.1\|WP_104411317.1\|181954_182239_+\|TrbC/VirB2-family-protein	gnl\|CDD\|368210	pfam04956, TrbC, TrbC/VIRB2 family. Conjugal transfer protein, TrbC has been identified as a subunit of the pilus precursor in bacteria. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains several VIRB2 type IV secretion proteins. The virB2 gene encodes a putative type IV secretion system and is known to be a pathogenicity factor in Bartonella species.	2.57003e-10
NZ_CP021256.1\|WP_080282870.1\|179688_180372_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|119397	cd06529, S24_LexA-like, Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The LexA-like proteins contain two-domains: an N-terminal DNA binding domain and a C-terminal domain (CTD) that provides LexA dimerization as well as cleavage activity. They undergo autolysis, cleaving at an Ala-Gly or a Cys-Gly bond, separating the DNA-binding domain from the rest of the protein. In the presence of single-stranded DNA, the LexA, UmuD and MucA proteins interact with RecA, activating self cleavage, thus either derepressing transcription in the case of LexA or activating the lesion-bypass polymerase in the case of UmuD and MucA. The LexA proteins are serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases. LexA sequence homologs are found in almost all of the bacterial genomes sequenced to date, covering a large number of phyla, suggesting both, an ancient origin and a widespread distribution of lexA and the SOS response.	1.00592e-16
NZ_CP021256.1\|WP_050486565.1\|179357_179699_+\|DUF45-domain-containing-protein	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	5.99979e-39

>NZ_CP021256.1|WP_011212795.1|176293_176887_+|CRISPR-associated-protein-Cas4
MDTSSYKLPVNMIRQYCFCPRIVYYHMVVGLKVAYPGWVQYGEEYQHKQQVLDKRRTLSKFKPISEQAVLRQNTMLEHPSYPFYGICDGIIEDELEIIPIELKSFASKISLGQKMQLTAYGMLSELIFEKPCTRGYIITGEKAKAKLIKIDEKSKFKVIEICAKIKKIFGTETLPYSTANGLQCIQCEFLNHCNDRF
>NZ_CP021256.1|WP_011212794.1|176013_176313_+|CRISPR-associated-endonuclease-Cas2
MQIRLYKEYIVSYDIRDNSIRRTIYERLKDIGLTPVQKSVFWGYLNEPEKRYLTNFLKKELAKQDTAFITPCKLAQEYEVNLINLELDELRKPDGHIIV
>NZ_CP021256.1|WP_027223966.1|175014_176007_+|CRISPR-associated-endonuclease-Cas1
MKHLTLSEQGSFCKLQGERILVFNKDQMVFEGTLNRLKTISIVKQGVTLTSNLLVACAMRGIQIFILDYSGKAVCSLQGGLHRTAKVRESQFKYIYTKEASNMAARFILAKIKNQSAVLKYFAKAKNRPENEKIILHAASQKMAGIVANITETNWIKLQDWRFTLLGFEGSAARIYWETVKEVNLVCSDFEGRRPRVNKDITNSMLNYAYSILSSWVWQAITNAGLELYAGILHTSKPGKPSLVLDLMEEFRPWCADRIIFKLHARAQKQNELTPALKKTLIGEMANLYAKPLPYHKRRISLESIIQRQVYHLSAVFSGEGKYKGYLFKW
>NZ_CP021256.1|WP_027223967.1|170899_175018_+|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12
MESSQILSPIGIDLGGKFTGVCLSHLEAFAELPNHANTKYSVILIDHNNFQLSQAQRRATRHRVRNKKRNQFVKRVALQLFQHILSRDLNAKEETALCHYLNNRGYTYVDTDLDEYIKDETTINLLKELLPSESEHNFIDWFLQKMQSSEFRKILVSKVEEKKDDKELKNAVKNIKNFITGFEKNSVEGHRHRKVYFENIKSDITKDNQLDSIKKKIPSVCLSNLLGHLSNLQWKNLHRYLAKNPKQFDEQTFGNEFLRMLKNFRHLKGSQESLAVRNLIQQLEQSQDYISILEKTPPEITIPPYEARTNTGMEKDQSLLLNPEKLNNLYPNWRNLIPGIIDAHPFLEKDLEHTKLRDRKRIISPSKQDEKRDSYILQRYLDLNKKIDKFKIKKQLSFLGQGKKLPANLIETQKEMETHFNSLLVSVLIQIASAYNKEREDAAQGIWFDNAFRLCELSNINPPRKQKILPLLVGAILSEDFINNKDKWAKFKNFWNTHKIGRTSLKSKCKEIEEARKNSGNAFKIDYEEALNHPEHSNNKALIKIIQTIPDIIQAIQSHLGHNDSQALIYHNPFSLSQLYTILETKRDGFHKNCVAVTCENYWRSQKTEIDPEISYASRLPADSVRPFDGVLARMMQRLAYEIAMAKWEQIKHIPDNSSLLIPIYLEQNRFEFEESFKKIKGGSSDKTLEQAIEKQNIQWEEKFQRIINASMNICPYKGASIGGQGEIDHIYPRSLSKKHFGVIFNSEANLIYCSSQGNREKKEEHYLLEHLSPLYLKHQFGTDNVSDIKNFISQNVANIKKYISFHLLTPEQQKAARHALFLDYDDEAFKTITKFLMSQQKARVNGTQKFLGKQIMEFLSTLADSKQLQLEFSIKQITAEEVHDHRELLSKQEPKLVKSQQQSFPSHAIDATLTMSIGLKEFPQFSQELDNSWFINHLMPDEVHLNPVRSKEKYNKPNISSTPLFKDSLYAERFIPVWVKGETFAIGFSEKDLFEIKPSNKEKLFTLLKTYSTKNPGESLQELQAKSKAKWLYFPINKTLALEFLHHYFHKEIVTPDDTTVCHFINSLRYYTKKESITVKILKEPMPVLSVKFESSKKNVLGSFKHTIALPATKDWERLFNHPNFLALKANPAPNPKEFNEFIRKYFLSDNNPNSDIPNNGHNIKPQKHKAVRKVFSLPVIPGNAGTMMRIRRKDNKGQPLYQLQTIDDTPSMGIQINEDRLVKQEVLMDAYKTRNLSTIDGINNSEGQAYATFDNWLTLPVSTFKPEIIKLEMKPHSKTRRYIRITQSLADFIKTIDEALMIKPSDSIDDPLNMPNEIVCKNKLFGNELKPRDGKMKIVSTGKIVTYEFESDSTPQWIQTLYVTQLKKQP
>NZ_CP021256.1|WP_187296496.1|170102_170741_+|hypothetical-protein
MMNDLAKILSLNNLLIKNNINPSENFETIYSQITDDGLKKEIESRIIDYFSKLSLPEHVTIYDQLLLSLREKDAIFTFNWDPFLFDAYKRNSDIVSLPQIFFLHGNVRIGACEACDKWGEKNTYCPECDIRFKDVPLLYPIKNKSYFQSSKYTALSWKKAESWFSEAFTITIFGYSAPTSDIEAVSLLNKVWLHISERQFEHVEVIDILMSS
>NZ_CP021256.1|WP_106220924.1|167292_169308_+|M3-family-metallopeptidase
MSTTVGLPQFSHIEVEHFKSHLDALLKNHLEEIDRLLKENHHYTWDNLIYPLDSLADELERFWSPFAHMHAVMDSEAIRESYEACLPLLSAYDAAIGHNQDLYEAIKSIDQYSLNPAQKKIIADNIQDFELSGVALSKANKKRFEAIQSRLAELSSKFENNVLDATHAYTIHITEAERLDGLPEHALNTAKELAHEKGLDGFVLTLEYPCFQAVITHAEDRALREEMYRAYVTRASDQGPNAGAFDNTPLIDEILSLRHEKAELLGFNNFAELSLATKMAASTNQVTEFIYDLIGRTRDKGKAEFRQLELFAQDKFNLSPVNPWDVAYLSEKRRQDLYSLSQEELRPYFPQPKVMQGLFAIVKKLFGMSIEEIEGVDVWHKDVQCYCIVDESNQTRGYIYTDLFARPHKRNGAWMDSMQSRRKLEDGTVQLPIATLTCNFAKPSANRPAMLSHDEVVTLFHEFGHCLHHILTQVDYLGGSGINGVEWDAVELPSQFFENWCWDEHALSLLTSHVDTGETLPSALYERLIAAKNFQSAMAMLRQMEFALFDFRIHQEYQAGKASFVAGILDDVRSKTSVVPIVPYNRFQHSFSHIFGGGYAAGYYSYMWAEVLSSDAFARFEEEGIFNPKTGHDFLKSILEAGGSRKAADAFVEFRGRPATIDALLRHNGIL
>NZ_CP021256.1|WP_106220922.1|165858_167196_+|hypothetical-protein
MTPIISHLLKMFPELTTQVETDSLNWTFNTRLKQLGPDFYSKVARLHPILNIEYSVLCQRLRYNLSSPDYSSPEQIKEQLIDALKLAELLEYTYQHYLVVPREVVRLRRHKAIYRELLTELSGYSFDLDSIEQESLKTSLSLTQAIREKTAQSNWYRIFISRSKRVINLLDNIDLGSKAFRDFVVLLDKYTNPFLAYLGWCFFAPRLFTNLFLILKHTIPGQWMGEKEKSLDWYHRFYAHLQRRWFELANDSVWFTVGILNCFVLVGALAPLSVYLSLFAFAFDVANTSLRAYIEIGRLQQLQKEYGELFDQEKNEDQKKIIKEYQDSISYRIKFEILRSFLSVGGAAAVVIAMALSVPALGFINPVIPLVGALLLLVLWGVSLYLTNKLDEYRPVDNIEKPAPSVINKLGFFASKNEKRESLHLSAKTEKDDEVGELIPTSAFN
>NZ_CP021256.1|WP_062726620.1|162518_163511_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNMLIVDGHGIQVIAERDPSKLPWKQLGVDIVFECTGFFTSRDAAMGHITAGAKKVLISAPAKGVDTTVVYGVNHTSIKASDVIVSNASCTTNCLAPVVKVLNDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKLDGFAMRVPVLNVSVVDLTFQAKRATSVEEINDIMRKAKSRILQINEDPLVSCDFNHNPASAIFDTTETKVIGNLVKVVAWYDNEWGFSNRMIDTAHQMMNC
>NZ_CP021256.1|WP_062726619.1|161317_162508_-|phosphoglycerate-kinase
MNLIKMSDIDLSGKRVLIREDLNVPIKDGMITSDQRLQAALPTIKSALDSGAAVIVLSHLGRPEEGKYEKKFSLEPVADYLKENLEYPVRFVKDYLNGLDVKPGELVICENVRFNPGEKSNDESLAKKLANLCDVFVMDAFGTAHRAQASTYGVAQYAPIAVAGPLLIRELEALNQVLKAPKKPIVAIVGGAKVSSKLSLLKQLVGMVDVLIPGGGIANTFLKAQGFEIGISLYEPDLLDEARHILILAKEKGCQIPLPTDVVVGKTFSETCPAFNKSLSNVAEDDMILDIGPETIRDYVDLIHDANTIIWNGPVGVFEFPQFAYGTRAIAIAIAESDAFSIAGGGDTLAAVDLYDLNQQISYISTGGGAFLECLEGKTLPAVAILQERAKHVKTN
>NZ_CP021256.1|WP_106220920.1|159909_161334_-|pyruvate-kinase
MLRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADASALQLIALVRKIADELNHPVAVMADLQGPKIRVGRFHNKSITLIDGQNFTLDCMAPDALGDINGVSVAYPNLANELSIGDHLLINDGLIELEVIEIAGSKIHCKVVEGGILTDLKGLNRKGGGLAARTLTEKDRNDLRTAIEAEVDYISLSFVKDAEDIRQARALMKDYGAKITPIIAKIERMEALDHLTDIIREADAIMVARGDLGVEVGAAEVPAIQKHIIEQTRLLDKVVITATQMMESMISNPQPTRAEVSDVANAILDGTDAVMLSAETASGLFPVKVISMVNKICLSAEKHASFFYHSDPETCHYQRADQAIAMATMHTANHFPIQAIITLTESGDTALWVSRHHSTVPIFAVSANKRTIGRLSLVNNVFPIYIDFHQFNPEGLNQQILHELIKSGHLEKRGYVLLTRGTQIGMPGGTNCMEIIPVV
>NZ_CP021256.1|WP_050486565.1|179357_179699_+|DUF45-domain-containing-protein
MSDWYKQKAFEVFSKRLDQLLSTAPWIKECPSINLRAMRSRWGSCAVNGKITLNTHLIKAPIACIDYVILHELCHHFEHNHSDKFYRLLNQVSPNWKQVKQYLDKAANLYLMT
>NZ_CP021256.1|WP_080282870.1|179688_180372_-|helix-turn-helix-domain-containing-protein
MTELNIKKEIGKRILEARKAKGLTLKALGELAGGLKQTRLTNWEQGVRTPGPKEIKSLARALDVSPAYLMCLSDELQFKEAKNPSQLIPLLDYRQACEATLHTGAESSGDKVFISVSTSLQPELSTDAFALKITDDSMMPEIRINDVLVIEPSVLPEPGDFVAVKINGKPETIICQYKKLSYTSSEFELLTLNDNWPNIKVSDDINVKIIGVLVQNLRCYKSPKVKS
>NZ_CP021256.1|WP_027223964.1|180526_181396_+|hypothetical-protein
MMDFVINGDELEAMCGLPHIQQLTYIRGIRPYMDVKTGIVGIKRRISHQSISEQLYVEPHQGIKSQSFSRDQVRRAVSGLVRAGLIEVQSEGMHLILKCLLASPHYSVQNKAAINPPQKATTKPRGESLENTGLFEVEALKADTVELQKAAIPHKDNYYIFLLSQFEKFWSLYPEKKSKSNAQAVFEELKPNAELCHTIINALTAQINHRDTMKLQGTWVPPWKYPANWLAQRCWEDELPTDALQEKHHAEHTKNTRKRHATEDLFCPPRDAEDREHNNVIQLQRYLQS
>NZ_CP021256.1|WP_021437111.1|181361_181724_+|hypothetical-protein
MSSSSKDTFKAERRIDLLFSKFAAFYGHVWRSQFKDEVFLKFAKKEWQEALADFTDMVLTRAILNCREFYELPPTLPQLLYCCRQIRKQESFYVVKDVYQPANKAVVSSCLQKCKELLAK
>NZ_CP021256.1|WP_011212799.1|181736_181940_+|carbon-storage-regulator
MLVLTRKAGQQILIGKGLIQMKVLKVENDIISIGIKAPSHIDIDREEIYFRKLRQEQEAANDAEMAI
>NZ_CP021256.1|WP_104411317.1|181954_182239_+|TrbC/VirB2-family-protein
MSKRAFQKIRTLYWGTVCLCAPSVSSAQNIESIINRTINYLQGGLARTVGVFCIIIAGYLCLARQKFPKEYFVMILVGMGIIFGGSSLYSTLIG
>NZ_CP021256.1|WP_011212801.1|182248_182530_+|VirB3-family-type-IV-secretion-system-protein
MSDLEISPIFNALTRPAMTAGVTFEYHMLNLIVSMCAFIGFSPLYGIIFIPLHVFGWLVCRYDTHFFTICAKRFLLPQAPNTSLWRVRAYEPF
>NZ_CP021256.1|WP_029346046.1|182516_184997_+|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase
MNLSKTLKHVYQEAKVSNLFPVTHLNSPCIFESQSGLVGSVIKVNGAAFEIEEAETLNHQRFLLHQALVSLDSRFIIYVTTHRQKISCPLIGEFKPGFAKDLDERYQQRFKDKNLYKNTLYITVVLKGDDTSKTGSWLQWAKSLSMKGNSELSEYHREQNIQILNRVVEQLQANLNPFGATILGKQDEALGFSELLQFLGLVVNAGQTISFKHPVYSPPIANSIPQSFRQEAKYPEGHLGQYLSSCQLLFGECIQFQGNTQKDCVFGAMLSLKKYPTNTASILLDSMLSLDCEFIATHTFAPIGRDSALDTISKKRSKLLSAEDKALSQTTALSDLEDGVASETLLLGAHHHTVMLLAPNKSLLDAAILEATKRYGSAGIVVVKETLGQEPAFWSQLPCNQHFITRASLITSQNFVDFCPLHNTQTSFSNENFLGGAVTLLETPSKTPVYFNYHARGSKTNPSKGHAAIFGGNNAGKTTLVNFLDAQMGRFGGRSFFIDRDESSKIYILASGNSSYIKIEPSNPIAMNPLQLPDTSENRSFLKSWFATLVQEDSERAIPSPIAEIINDCIDYSFEQLAPEFRTLSHLSQFLPVDFPRWPHLKRWLKRNDSRIDGEFHWLFDNQHDALNLDFDKVGFDVTYLMDQVQSIIATPVYLYLLHRMRQCLDGRLTSFIIAEAWQLFASPFWEKALREWLPTIRKKNGHFIFDTQSPKTITDSPIKHIVLDNLATLIAFPNPLADRETYMEHLKLTEAQFEAIKENTPESRIFLYKQDHEAFLCKLDLSSLSQYIRVFSANTQSVKLLDDIMQEVGHDPELWLPVFYERSKK
>NZ_CP021256.1|WP_029346047.1|184993_185704_+|hypothetical-protein
MKRAACFLIAAMGISSASHADILGVEDAQLILLAMKQLGELQEQYRVLSDTYQTARNQLDNLNQLKSMNSGHYGFGDFNNSLDSLQSWQSPVSTWQDALQNLSGGNQQRYQALMDAYEKNHPALDENSYARFTTPANAARFKEDKAVNRAVMVQTTESYNEINKHMEALHKLSQQIEKTPNTKGAIDLNSRLITEIGFIQLMSLRLQALISQQAAQENLSALQERAEMAKFNRLPK
>NZ_CP021256.1|WP_011212804.1|185718_185865_+|hypothetical-protein
MKWLLSVLMIALLSGCSKPPDLDSPCHHFGQYCPQYPINDEPIMELTK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP021256_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021256_2

1680337-1680444

Orphan

Consensus_repeat	Method
ATCTTACAGGCAATTTGGGTATCACCTCTCAATCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021256_2

>merge|NZ_CP021256|2|1680337-1680444|CRISPRCasFinder
ATCTTACAGGCAATTTGGGTATCACCTCTCAATCAGCACATAAGAACAATCGAAGTCCCAAATGTAGAATATATCTTACAGGCAATTTGGGTATCACCTCTCAATCAG

>NZ_CP021256|2|2|1680337-1680444|CRISPRCasFinder
ATCTTACAGGCAATTTGGGTATCACCTCTCAATCAG	CACATAAGAACAATCGAAGTCCCAAATGTAGAATAT
ATCTTACAGGCAATTTGGGTATCACCTCTCAATCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021256.1\|WP_161514867.1\|1675414_1676407_+\|tRNA-dihydrouridine(20/20a)-synthase-DusA	unknown	unknown	gnl\|CDD\|236991
NZ_CP021256.1\|WP_106221595.1\|1667555_1668890_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP021256.1\|WP_011213745.1\|1671598_1672792_+\|alanine-transaminase	unknown	unknown	gnl\|CDD\|181268
NZ_CP021256.1\|WP_027226973.1\|1688797_1689940_+\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_CP021256.1\|WP_062727988.1\|1681742_1682354_-\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NZ_CP021256.1\|WP_106183747.1\|1672795_1673605_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226706
NZ_CP021256.1\|WP_027226972.1\|1687849_1688797_+\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|273075
NZ_CP021256.1\|WP_106183754.1\|1684543_1686190_+\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224938
NZ_CP021256.1\|WP_106221598.1\|1680760_1681507_-\|cell-division-protein-ZapD	unknown	unknown	gnl\|CDD\|235389
NZ_CP021256.1\|WP_106221593.1\|1666178_1667435_-\|phospholipase	unknown	unknown	unknown
NZ_CP021256.1\|WP_106221600.1\|1682795_1684397_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP021256.1\|WP_062726493.1\|1671174_1671540_-\|Xcc1710-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|240187
NZ_CP021256.1\|WP_106183748.1\|1673594_1675334_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|182944
NZ_CP021256.1\|WP_027226965.1\|1679194_1679596_+\|8-oxo-dGTP-diphosphatase-MutT	unknown	unknown	gnl\|CDD\|239517
NZ_CP021256.1\|WP_161514869.1\|1686442_1687777_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NZ_CP021256.1\|WP_062727985.1\|1689923_1690643_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|273783
NZ_CP021256.1\|WP_062726494.1\|1668895_1671100_+\|GTP-diphosphokinase	unknown	unknown	gnl\|CDD\|223394
NZ_CP021256.1\|WP_106183750.1\|1676507_1679198_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|183860
NZ_CP021256.1\|WP_062727984.1\|1690639_1691278_+\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|234625
NZ_CP021256.1\|WP_062727987.1\|1682325_1682799_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP021256.1\|WP_161514867.1\|1675414_1676407_+\|tRNA-dihydrouridine(20/20a)-synthase-DusA	gnl\|CDD\|236991	PRK11815, PRK11815, tRNA dihydrouridine(20/20a) synthase DusA.	4.41016e-171
NZ_CP021256.1\|WP_106221595.1\|1667555_1668890_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP021256.1\|WP_011213745.1\|1671598_1672792_+\|alanine-transaminase	gnl\|CDD\|181268	PRK08175, PRK08175, aminotransferase; Validated.	0
NZ_CP021256.1\|WP_027226973.1\|1688797_1689940_+\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	1.02717e-116
NZ_CP021256.1\|WP_062727988.1\|1681742_1682354_-\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	2.6568e-83
NZ_CP021256.1\|WP_106183747.1\|1672795_1673605_+\|hypothetical-protein	gnl\|CDD\|226706	COG4255, COG4255, Uncharacterized protein conserved in bacteria [Function unknown].	4.07258e-05
NZ_CP021256.1\|WP_106183754.1\|1684543_1686190_+\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	9.74597e-36
NZ_CP021256.1\|WP_106221598.1\|1680760_1681507_-\|cell-division-protein-ZapD	gnl\|CDD\|235389	PRK05287, PRK05287, cell division protein ZapD.	1.41194e-75
NZ_CP021256.1\|WP_106221600.1\|1682795_1684397_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.20894e-88
NZ_CP021256.1\|WP_062726493.1\|1671174_1671540_-\|Xcc1710-like-domain-containing-protein	gnl\|CDD\|240187	cd05560, Xcc1710_like, Xcc1710_like family, specific to proteobacteria. Xcc1710 is a hypothetical protein from Xanthomonas campestris pv. campestris str. ATCC 33913, similar to Mth938, a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome. Their three-dimensional structures have been determined, but their functions are unknown.	3.51298e-46
NZ_CP021256.1\|WP_106183748.1\|1673594_1675334_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|182944	PRK11070, PRK11070, single-stranded-DNA-specific exonuclease RecJ.	0
NZ_CP021256.1\|WP_027226965.1\|1679194_1679596_+\|8-oxo-dGTP-diphosphatase-MutT	gnl\|CDD\|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	6.17187e-55
NZ_CP021256.1\|WP_161514869.1\|1686442_1687777_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NZ_CP021256.1\|WP_062727985.1\|1689923_1690643_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|273783	TIGR01738, Pimeloyl-_methyl_ester_esterase, pimelyl-[acyl-carrier protein] methyl ester esterase. This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	1.10778e-54
NZ_CP021256.1\|WP_062726494.1\|1668895_1671100_+\|GTP-diphosphokinase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_CP021256.1\|WP_106183750.1\|1676507_1679198_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|183860	PRK13104, secA, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP021256.1\|WP_062727984.1\|1690639_1691278_+\|dethiobiotin-synthase	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	4.62204e-69
NZ_CP021256.1\|WP_027226972.1\|1687849_1688797_+\|biotin-synthase-BioB	gnl\|CDD\|273075	TIGR00433, biotin_synthase, biotin synthase. Catalyzes the last step of the biotin biosynthesis pathway. All members of the seed alignment are in the immediate gene neighborhood of a bioA gene. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	1.7754e-166

>NZ_CP021256.1|WP_027226965.1|1679194_1679596_+|8-oxo-dGTP-diphosphatase-MutT
MKVAVAIIIDEKQRILITQRPLHAAHGGFWEFPGGKLEPQESGEDALVREIREELGIVVNEYRFLGYVDYDYPDKHIQLIIFMVTRFTGNPLCLEGQLNMKWVKKEELNINDFPKANHAVFDLINAPEFQYQA
>NZ_CP021256.1|WP_106183750.1|1676507_1679198_+|preprotein-translocase-subunit-SecA
MLSTLIKKMFGSRNERTLRRMEKSVMAINAFEPKMQALSNEELAGKTQQFKERFNNGESLDELLAEAFATVREVSLRTLGLRHFDVQLIGGMVLHEGNIAEMRTGEGKTLVATLPAYLNAISGRGVHIVTVNDYLAKRDSQWMKPIYEFLGLTVGVIYPDMSHKEKQEAYKADIVYGTNNEYGFDYLRDNMAFSLTDKVQRELNFAIVDEVDSILIDEARTPLIISGAAEDSSELYIKINSLIPQLKKQEEEGGEGDYTVDEKQKQAHLTDAGHLHIEELLTKAKLLDPGESLYHASNIMLMHHVNAALKAHAMFHKDIDYIVKDNQVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGVPIQNENQTLASITFQNFFRMYNKLSGMTGTADTEAYEFQQIYNLEVVVIPTNKPMVRKDEADLVYLTQADKFQAIIEDIRECGVRRQPVLVGTVSIEASEFLSQLLKKANIKHQVLNAKFHEKEAQIIAEAGRPGAVTIATNMAGRGTDIVLGGSLAADLANLPADASEQEKEAVKKEWQKRHDEVIAAGGLRIIGSERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDNLMRIFASDRVASMMRRLGMQPGEPIEHSLVTRAIENAQRKLEGHHFDVRKQLLDYDNVANDQRQVIYTQRSSIMEMTDTQEVVEMMREEVMNSLVDTYIPPQSLEDQWDPQALSDILSDEFKIKAPVTDWINEDHSIQPEQIKEKILALAIEHYDEKVRKVGRPVISQFEKSIILQTLDNHWREHLAAMDQLRQGIHLRGYAQKDPKQEYKKEAFSLFTMMLDNLKYEVIRILSSVEIQTEEDAHVVEEQRRADQIKKMNLMHENLSENDEASETQTFRRQEKKVGRNDPCPCGSGKKYKACHGSLV
>NZ_CP021256.1|WP_161514867.1|1675414_1676407_+|tRNA-dihydrouridine(20/20a)-synthase-DusA
MVNSIFSKLSIAPMIDWTNSPFRTLMRLLAPNALLYTEMQTTGAVQNNPDRALYFNSVEHPIAIQLGGADKSALVKCAIIAEQKGFNEINLNLGCPSDKVQAGQFGACLMKEPEHVADCIRAIKQVVGIPVTAKTRIGIDTQDSYEFFRSFSLHLVEAGCDKLIVHARKAWLNGLNPKQNRTIPPVNYDYVYELKKEIPHIFITINGNILSIGEINSHLNHVDGVMLGRLACDNPYQIAEIHQALYPQFIKMKRSQLLINYLDYWLDQSRGNVSLSILVKPLFNLAFGLSGAKHWKKKLMNIVQEKNTSGFSELIQYLLHLEATNHVECV
>NZ_CP021256.1|WP_106183748.1|1673594_1675334_+|single-stranded-DNA-specific-exonuclease-RecJ
MLIKQRQQPEHTVNLPNVPDVLKRIYITRGISDESQLDKQLQTLLPFHSLKGINEACLRLESALRSEQRILIIGDFDADGATSTALAITALRAMGAKFVEYLVPNRFEFGYGLTPAIVEVASKWQPHLIITVDNGIASFEGVDAANKMGIDVLITDHHLPAESLPDACAIVNPNQPGCLFPSKSIAGVGVIFYVMLALRRHLSKSNWFSEINLPEPNMASFLDLVALGTVADVVGLDQNNRIMVNQGMMRIRQGQCREGIKALIEIAGRDYSRLRESDLGFAIAPRLNAAGRLDDMSLGIECLITTDPKMARSFCQQLDELNLERRQIESEMKEQAMLALEKLSINDEENKHLPVALCLHDKTWHQGVIGILAGRMKERYHRPVIAFASVSEQELKGSARSVPDLNIRDVLAAVNKDNPGLILKFGGHAMAAGLSINPELLNDFRSAFVSEVLKHLDLSQCEGEILTDGPLQPHELNLETAQLIQQAGPWGQAFAEPVFDNVFEILDQRIVGKNHLKMTLISSQGGEPLDAIAFNVDLKSWPNHRIKYIHAAYKLDINFYQGRTRLQLLIQAMNIIKQA
>NZ_CP021256.1|WP_106183747.1|1672795_1673605_+|hypothetical-protein
MDVIINTEGSCDSKEGRLLKSQGLAVLNLLACGGYNLANPPAGSLLKSSRNLEGDWVILTPMHWQASHNDAVIVAIDNDLRVTDEEVKYWFDLYSAYLAEEGMSLYFYDKYTWLLRVDDKPPLNAKPIYQVLNKSLMPELSHLDETMYWQKFFTESQMFFSSNPRKSLINGIWAWGSGQLKDKNTISICTDKHFLDIAQVYSSSVTLYDPSVNLSKFEVVLLHNIDSLSESHQVEIKKIPAHWYWNNCILIKAKSHWFTRLWRSLTHAD
>NZ_CP021256.1|WP_011213745.1|1671598_1672792_+|alanine-transaminase
MSQFPRIKRLPPYVFNTINQLKMEARARGEDIIDFGMGNPDQPTPPHIVNKLIEVAQRPDTHRYSMSKGIPRLRRAMATWYLRHYDVHLDSETQILATIGSKEGLAHLALAISGPGDTVLVPDPAYPIHTYGFIIAGANVKQIPLIDEVQFLAAVEDAINRTWPKPKALVLNFPANPSTHCVEYEFFEKVVDLAKRNNIWIIHDLAYADIVFDGYKAPSILQVPGAIDIAIETYSMSKSYNMPGWRVGFACGNEELVAALTRIKSYLDYGTFTPIQVAAITALEGPDDCVLEIRNLYEKRRNLLCDGLNDIGWEVSKPKGTMFVWAPIPLNYRAMGSLEFSKYLLKEAQVAVSPGIGFGQQGDGYVRFGLIENKDRIRQALRNLKALFKRDGLLKAI
>NZ_CP021256.1|WP_062726493.1|1671174_1671540_-|Xcc1710-like-domain-containing-protein
MNINLETAEQHAVQAYSDKKIQINSIIYESSLIVSKKEIITDFVIKDIQDINDSYIDLLLGSNPELIIIGHLQTGKMLPVTLISQLSQKRIGIECMSIGAACRTYNVLLSEHRAVVAGFIL
>NZ_CP021256.1|WP_062726494.1|1668895_1671100_+|GTP-diphosphokinase
MVRVKDTTPLTPDGSIDVEMWLHHLGSKGYLDNLELVRAACTLSQLAGQDHATETGQTCLQQGLSMADLLADLEVDQETLAAAIIFENVHYADLSIDDVEEQLGHNIAKLVKGIEKMSAMNNFQALNKYPQNKNQIDNIRKMLLAMVDDVRVVLIKLAECLCILRTAGHLSETVRKQLATEAMEIYAPLANRLGIGAIKWEMEDLAFRHLHPEEYKAIAKGLKAKRLERDSFVNRIVEQLEHQIRATGARHFAVYGRSKHIHSIYKKMKRKNVSLDEIYDATAVRILVDTEAQCYEVLGMVHTLWKQIPAEFDDYIINPKSNGYQSLHTAVEGPEGRVFEVQIRTFHMHDLAEMGVAAHWKYKEGAVSQKESHERKIEWLRDVLAWHQEMAANKGVAENVTTEFLEDRVYVFTPDGDVLDLPHGVTPLDFAYHVHSNLGHRCRGAKVNGHIVPLTYQLKTGDRVEVLTGKEIKPSRDWINPHLNYLKTARAKAKVLHWFKMQDYEDNVRDGRELLEKELKSLGIKSDKLNEVLTALNYKKADDLYASLGRGDIKIGQIINRLAPPDTSEQNLQKFVRQQQKPEVTGSDLRIEGVGNLLTFMARCCQPVPGDEIVGYITIGRGVSVHRKDCPNIIHASEKQKRRFIQVNWGTATRENYVVDVLIKAFDRSELLKDVTSLLSNEKAHVYALQTHSNKHENMAYITLTVEIDGLNSLSRLLTKLEQIPNVLEARRQL
>NZ_CP021256.1|WP_106221595.1|1667555_1668890_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MRKVKPKLNLTPQTAQIVNLSHDGKGIARINGKATFIQGALPGEVVEFQYTRVKKDFDEGKLLSIVEPSTLRVEPKCPHYQMCGGCSLQHMSAEEQIRFKQSHLLDLLSRYGHTEPQTVLLPLTSHHWNYRNKARLSTRFVEKKQTALIGFRERNNPRFITEINQCPILNSKIDADIVHLRKLIDTMEDKHCIAQIEVAAGDNEVALIFRNLSPLTEQDELSIQEFAQQFQYKVFLQPGGPDSVFCFYPSNTHDYLSYELPDYQITFQFHPNDFTQVNAELNRKMVTQAIQLMELKNSDIVLDLFCGLGNFSLPMAKHCSRVIGVEGNKNMVERAYMNAKSNHITNVDFYAANLDDVMEVRNLVNTSFSKVLIDPPRSGALEIVKQIDAIDPERIVYVSCNPITLARDTDILVNQKGYVLITAGVMDMFPHTAHVESIALFQKG
>NZ_CP021256.1|WP_106221593.1|1666178_1667435_-|phospholipase
MLKNITPALSLSLLITHNICANEPSSIKTISQPTTIQFLEKFGAGFANLEHKNLGDRVQLYLPGHDSKTGIVKLTLPNGSKLSYGEIVMYGGDMFGNPAKPISNCSEKNRLACFQAQFDALGILGNKQDKRCSNPLNQITHLNQFFISLASELEKSKQNGTNDWDYYNQHDTAISKELNKLTCGGSIISSFIPFGNYIKLAEVNYDHFVPDSLVAYKTGHRFALETALKAYEKKQQGFIYEAHKLLELAYAQNAFANHYLTDSFSAGHMRTPRRAIGHDILLPSVLNLLIANLMHNEDNQHGLNVVNYEGISWLAYGDGYLYKPEAELQRMVILDAMQRSADSIHSTFMNGVIPEHYPEMDVFPDYSKIEQINDTAPLFKVENGVLLKRVNNKDHYDHHWTKYWSGLVTLIEFQVNKN
>NZ_CP021256.1|WP_106221598.1|1680760_1681507_-|cell-division-protein-ZapD
MHNHMITFQLATHFLSRIALRLEYLFKTINEACSESHEVIHRFALKNIIEIVEIIEKPELKSRFIKELIRIEHVLKKPNLLNHSELFDDLETQIHVLNHVPGRFSNRIHDDEFLKTLRQIHHPNTKECEFNSPHLVLWFDSDPLLRQKTISQWVSCLKDLEDTVKVYLSLLRGITQYTPIRANNGFYQHSLSPKSLNHLILLRMDKTLKMIPKIQLGHHSLTIRLYELVTGQEIRDKTIDLEIAFCQI
>NZ_CP021256.1|WP_062727988.1|1681742_1682354_-|dephospho-CoA-kinase
MVYSVGLTGNIASGKSTVAEFFSELGIDVIYADRISKELTSKNTPCYQNIVSHFGSSVVLKNGDLDRKRIRDIIFSNSNERLWLEDLLHPAIRKKIEEQLIVCSSPYCLIEIPLLYNKHHYPYLQKILLVIAPLECQLDRIVKRDHCTKEQALAILATQPNLEQRLETADDVLVNESGLSELKEKVNKLHRKYLKEAKIKQKQ
>NZ_CP021256.1|WP_062727987.1|1682325_1682799_-|hypothetical-protein
MRNCIFYGLLLLIGLSNEGFTAPMVKKGNFWKCITYDKANKAWTAQSSYRKVAINVAFAACKKESQFPASCKTSLSNCEGFIDGVSTRPMWRCTAIDINAQPWESNFYSNRDDAALAAQAFCKENSTLPATCYINMVTCANKNEGAHSHGLFSGTNW
>NZ_CP021256.1|WP_106221600.1|1682795_1684397_-|EAL-domain-containing-protein
MSKVIHKLSLFLYKKFKIIWIFFTIAILISAFYTNWNLNQKRAYKDLKEVAINLSNNIDGFIEDLLQEIYTLPVYGKKIVDCKSDLYPFLEHIILNNPKISGVIISDNKHKLFCSTLPNNNKDLIATSTRSRSISGPYKLPLFDQPVYLIQQKMGNYLIGIFVIASVLKNELQTEKKQSTAIALYNEDEKKNILRIQYTEQNKSWILSKTQETKKQNSPLSLFAIEKLQSINGISVVVSENSKTILHNFWYSQIITIFIILICSFILYVLIQNMMTKRYSLQGAIKLAIKNEEFYPVYQPLFDCDKERFSGVEVLLRWENEDSQIIMPDFFIAEAEATGLIVPITLQIIEIAFKEFRSLLEERSYFHLAFNISALHFTDSVFFNHFYKLIEKYNISPHQIIFEITERELLDKNDTVFINKMQELRQTGFSLAVDDYGTGHASISYLQHFPFNYLKIDKLFVQAIGSNDIIESLNDAIIQMAKGLNLVTIAEGVETKDQANYLANNGVRLQQGWYYSKGLSIAELTALLKGEKI
>NZ_CP021256.1|WP_106183754.1|1684543_1686190_+|D-alanyl-D-alanine-carboxypeptidase
MKKRHSKRLLTYIYLLMKSIFLVIMMQQPSHSMDTRISINKLPGDINKVMNKPIYKHAMWGLRVVDLDTGNVLLNLNSSMLFYIGSVRKIFSVGELLNERGTDYQSLTTVHHDGEVRNGNLNGNLVLVASGDLTMGGRTLPGGHVAITEYDHNEANSLGNAIITQTNPLAGYQYLAKQVYKAGIHSISGDIVIDDRLFDPFDFRGEFHVTPIFINDDVVDIVILPSLINDKANVSWLPHSSAFTVINQLLTANPYEKYNLELEPKLPVCIGKPGCYGIIKGHLPVNFIPPLTNSYPLVQTFRITKPSNYARTIFIEALQAAGVNVSTIDKIKENPTKLLKSTNSYNKNNKIATLKSLPFGEHAKYILKVSYNIGADTSLVLYGLTKGVRSMIESLNVEKKILAKKYGIYPSEYQFVDGSGGGETKATNTAIIKWLIIMSKRPVFNTFYNSLPILAVDGSLGSINSFQSDPTLSGATGRVHAKTGTYVLGNESGMIIKGRSLAGYIISKKNHRLAFALVVNNIPIQSLEDLFAVAQDQGIIASILWRDY
>NZ_CP021256.1|WP_161514869.1|1686442_1687777_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MVNIDQLIAKDLKHIWHPCSQMKDFETCPPIVINKAQGSYLYTNEGPLIDAISSWWCKSLGHGHPAVIAAIKNQLDCFEHVISANTTHPAAVELAEKLSEITGKQHVFFASDGSSAVEIAMKLAIHASQIKGNKNKNQFIALKNGYHGETIGTMSVSDLGIYKAPYASFGVQCHYIDDIPYVTGSQDPLWKNCDTYWNKVVQQLNKICDRVCAVLLEPIIQGAGGMLCYSADFLAKISLWAKEKGIYLIADEIMTGIGRTGEWLACDHAHIKPDLICLSKGLTSGSIPFSCVMIDSALFDLFYDDYHVGKSFLHSHTYSGNPLAISAALATIKTIEQDNLLMHSQELGEIMFSYLQDIARDSKKLVNVRGIGAVVAADLIESSYTRIGFKIYQEAIRQGALIRPIGNTLYWLPPLNTDKKIIGKLAEITLNSIEEAYNKAQGDE
>NZ_CP021256.1|WP_027226972.1|1687849_1688797_+|biotin-synthase-BioB
MSEEKKQWSISDIEAIYEQPFNDLLYQAHTIHRTFHNPNSLQFATLLSIKTGACPEDCGYCSQSGHYKTHVEKEKLMSVDEVLQCAKEAKEGGAKRFCMGAAWRCPPDKAMPQLKEMIEGVKSLGLETCMTLGMLTKEQASHLKEAGLDYYNHNIDTSPSYYDKVVTTRKFSDRLDTLNNVRSAGINVCCGGILGLGETRADRIEFLLTLVNMETPPESVPINRLIPVEGTPLAQAERVEGIELVRTIATARILMPKSAIRLTAGRTEMSDELQALCYFAGANSVFIGDKLLTEDNPQRAKDKVLFNKLGLTEMV
>NZ_CP021256.1|WP_027226973.1|1688797_1689940_+|8-amino-7-oxononanoate-synthase
MALNIKIKEYTTQLQEQGLLRTRQISETNNSDSIRFDSNDYLSLTEDRRIAKAYQKGYELYPCGSGASMVLSGYHIGHQALERTFAEILGVDDCLLFSSGYCANLAITALLGRLRTHCFIDKSVHASIYDGLVLSQVTYSRYIHNDMRALSTLLKSHLDDSVLITEGIFSMSGQIAPLSTISSLCKEHGTELFVDEAHAFGVIGPQGMGSVPGHGLTQNEVPLRVIPFGKAFASQGAVVAGRKDWIDALLQAARSFIYSTAISPALCYGLLKTLEVIVAADYRRIKLTHLVAQFKELIKSSPLNWLDSDTPIQQLRLGCPHKALHYASELKKAGFYCSAIRSPTVNSSSSGLRIIINYKHTAEQIIGLFNKLHLIHEYSS
>NZ_CP021256.1|WP_062727985.1|1689923_1690643_+|alpha/beta-fold-hydrolase
MNIHLDKYGQGMPLVLFHGWGFDGQIWLPIIPYLQSDYQIILVDLPGFGLTPMMDWESFKKNLLKQLPEKFALAGWSMGGLYATRLAIEEPSRVQYLINITSSPRFISDVDWPGVAEEVFVNFYNNLSKNINKTLKEFISLQLNKIKFDFKPGNPPSPEGLAFGLEILAKWDLREQLKQISIPTVYLFGRLDPITPVKTMTIMEKNYPHFKYVLFSRAAHMPFLSHTDLFIKMMDEFIK
>NZ_CP021256.1|WP_062727984.1|1690639_1691278_+|dethiobiotin-synthase
MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSDNQLVNSDALLHQQQNHLPLDIINPWRFRLPVSPHISAREDGASIDVHKVADYCLNLRLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTNIPVILVVGMKLGCINHTLLTQEVLEINKIRCQGWIANCIDQDMLMLEDNISTLEVKLKYPLLATTSYGGKISDICLSSL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021256_1	1.15\|178131\|34\|NZ_CP021256\|PILER-CR,CRISPRCasFinder,CRT	178131-178164	34	NZ_CP021285	Legionella pneumophila subsp. pneumophila strain Allentown 1 (D-7475) plasmid unnamed2, complete sequence	35628-35661	2	0.941
NZ_CP021256_1	1.3\|177282\|33\|NZ_CP021256\|PILER-CR,CRISPRCasFinder,CRT	177282-177314	33	NZ_CP010910	Candidatus Pantoea carbekii strain US plasmid pBMSBPS3, complete sequence	6349-6381	6	0.818
NZ_CP021256_1	1.6\|177494\|36\|NZ_CP021256\|PILER-CR,CRISPRCasFinder,CRT	177494-177529	36	MH542234	Staphylococcus phage Terranova, complete genome	23165-23200	8	0.778
NZ_CP021256_1	1.6\|177494\|36\|NZ_CP021256\|PILER-CR,CRISPRCasFinder,CRT	177494-177529	36	MH321490	Staphylococcus phage Quidividi, complete genome	20804-20839	8	0.778
NZ_CP021256_1	1.6\|177494\|36\|NZ_CP021256\|PILER-CR,CRISPRCasFinder,CRT	177494-177529	36	MH321491	Staphylococcus phage Twillingate, complete genome	22950-22985	8	0.778
NZ_CP021256_1	1.19\|178413\|34\|NZ_CP021256\|PILER-CR,CRISPRCasFinder,CRT	178413-178446	34	NC_019775	Anabaena cylindrica PCC 7122 plasmid pANACY.06, complete sequence	3240-3273	8	0.765
NZ_CP021256_1	1.11\|177850\|33\|NZ_CP021256\|PILER-CR,CRISPRCasFinder,CRT	177850-177882	33	NZ_CP047444	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-7	21594-21626	9	0.727

1. spacer 1.15|178131|34|NZ_CP021256|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021285 (Legionella pneumophila subsp. pneumophila strain Allentown 1 (D-7475) plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.941

gtgacatattagaaaccatggctccaaagctata	CRISPR spacer
gtgacatattagaaaccatggctccaaagctgtt	Protospacer
*******************************.*

2. spacer 1.3|177282|33|NZ_CP021256|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010910 (Candidatus Pantoea carbekii strain US plasmid pBMSBPS3, complete sequence) position: , mismatch: 6, identity: 0.818

ataaactataatttccacaacacaataaactat	CRISPR spacer
ttaaactataatttttacaacacaataatattt	Protospacer
 *************..************  * *

3. spacer 1.6|177494|36|NZ_CP021256|PILER-CR,CRISPRCasFinder,CRT matches to MH542234 (Staphylococcus phage Terranova, complete genome) position: , mismatch: 8, identity: 0.778

tctgttcaccctacacaaaagcccgtagctttaatg	CRISPR spacer
ttattacaccctacacaaaaaccagtagctttattt	Protospacer
*.  * **************.** ********* *

4. spacer 1.6|177494|36|NZ_CP021256|PILER-CR,CRISPRCasFinder,CRT matches to MH321490 (Staphylococcus phage Quidividi, complete genome) position: , mismatch: 8, identity: 0.778

tctgttcaccctacacaaaagcccgtagctttaatg	CRISPR spacer
ttattacaccctacacaaaaaccagtagctttattt	Protospacer
*.  * **************.** ********* *

5. spacer 1.6|177494|36|NZ_CP021256|PILER-CR,CRISPRCasFinder,CRT matches to MH321491 (Staphylococcus phage Twillingate, complete genome) position: , mismatch: 8, identity: 0.778

tctgttcaccctacacaaaagcccgtagctttaatg	CRISPR spacer
ttattacaccctacacaaaaaccagtagctttattt	Protospacer
*.  * **************.** ********* *

6. spacer 1.19|178413|34|NZ_CP021256|PILER-CR,CRISPRCasFinder,CRT matches to NC_019775 (Anabaena cylindrica PCC 7122 plasmid pANACY.06, complete sequence) position: , mismatch: 8, identity: 0.765

atctcatatccagcctctaaattttttagtaaaa	CRISPR spacer
attttttcaccagcttctaatttttttagtaaat	Protospacer
**.*. *  *****.***** ************

7. spacer 1.11|177850|33|NZ_CP021256|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047444 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-7) position: , mismatch: 9, identity: 0.727

tttctatgttcagttttccaatttattattgac	CRISPR spacer
tgaaactgttcagttttccaatatatttttaat	Protospacer
*     **************** **** **.*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

596707 : 643377

Alteromonas_phage(11.11%)

integrase,transposase,tRNA,protease

attL 611710:611724|attR 647843:647857

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062726676.1\|596707_597385_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_062726683.1\|597396_598521_+	M42 family metallopeptidase	NA	NA	NA	NA
WP_106221138.1\|598597_600085_+	Dot/Icm T4SS effector AnkC/LegA12	NA	NA	NA	NA
WP_062726678.1\|600293_601436_+\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_027228868.1\|601438_602353_+\|protease	protease modulator HflC	R4VJU7	Alteromonas_phage	2.3e-09	29.6
WP_106221140.1\|602487_603783_+	adenylosuccinate synthase	A0A285PX35	Cedratvirus	9.3e-73	34.9
WP_106221141.1\|603995_604565_+	cupin	NA	NA	NA	NA
WP_027228865.1\|604718_605177_-	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_106221143.1\|605306_606041_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_062726999.1\|606037_606685_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_062727000.1\|606668_607337_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.5e-26	38.0
WP_062727001.1\|607333_608551_+	argininosuccinate synthase	NA	NA	NA	NA
WP_161514756.1\|608543_609779_+	argininosuccinate lyase	NA	NA	NA	NA
WP_080463904.1\|609781_610897_+	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_062727003.1\|610986_612462_-	adenosine deaminase	NA	NA	NA	NA
611710:611724	attL	NA	NA	NA	NA
WP_106221146.1\|612634_613750_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_028378023.1\|613822_615160_-	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	5.9e-22	27.7
WP_062727005.1\|615241_616384_-	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_106221147.1\|616370_617915_-	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_106183323.1\|618019_618316_-	hypothetical protein	NA	NA	NA	NA
WP_106221149.1\|618390_619662_-	phospholipase	NA	NA	NA	NA
WP_061504501.1\|619940_621062_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_062727009.1\|621247_621964_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	6.3e-23	39.6
WP_062727010.1\|621974_622772_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_161514801.1\|622804_624157_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_161514800.1\|624327_626658_+	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_027228847.1\|626773_627274_+	OmpH family outer membrane protein	NA	NA	NA	NA
WP_062727012.1\|627287_628307_+	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_011214749.1\|628424_628877_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_011213138.1\|628873_629644_+	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_062727013.1\|629647_630052_+	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_106221154.1\|630073_631354_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.5e-94	46.2
WP_161514799.1\|631615_632659_+	GNAT family N-acetyltransferase	A0A2K5B2B6	Erysipelothrix_phage	1.1e-10	31.0
WP_062727016.1\|632813_633077_+	hypothetical protein	NA	NA	NA	NA
WP_080463913.1\|633252_634083_-	aldo/keto reductase	NA	NA	NA	NA
WP_062727018.1\|634379_635228_-	hypothetical protein	NA	NA	NA	NA
WP_028378031.1\|635563_636031_-	hypothetical protein	NA	NA	NA	NA
WP_062727019.1\|636014_636773_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_027228837.1\|636738_637347_-	uridine kinase	NA	NA	NA	NA
WP_062727020.1\|637343_637811_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_062727021.1\|637807_638806_-	phosphotransferase	NA	NA	NA	NA
WP_106221158.1\|639115_640099_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	3.9e-31	31.7
WP_042646482.1\|640384_642061_+	putative DNA binding domain-containing protein	NA	NA	NA	NA
WP_042646536.1\|642153_643377_+\|integrase	site-specific integrase	Q9T1P3	Pseudomonas_phage	2.6e-24	30.2
647843:647857	attR	NA	NA	NA	NA

DBSCAN-SWA_2

915533 : 1035480

104

Enterobacteria_phage(14.29%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106221264.1\|915533_918299_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.4e-158	40.0
WP_062727184.1\|918556_921604_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	5.0e-61	22.4
WP_106183406.1\|921724_922987_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_010946459.1\|923226_923631_+	hypothetical protein	NA	NA	NA	NA
WP_062727182.1\|923692_924130_+	hypothetical protein	NA	NA	NA	NA
WP_027223766.1\|924254_924566_+	BON domain-containing protein	NA	NA	NA	NA
WP_106221266.1\|924593_925847_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	4.0e-97	51.2
WP_010946463.1\|925849_926317_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_161514900.1\|926375_926819_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_161514899.1\|926811_927768_+	thiamine-phosphate kinase	NA	NA	NA	NA
WP_106183410.1\|927847_928330_+	phosphatidylglycerophosphatase A	NA	NA	NA	NA
WP_060871634.1\|928329_929382_+	AI-2E family transporter	NA	NA	NA	NA
WP_060871635.1\|929373_930111_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_028379500.1\|930120_930759_-	porin family protein	NA	NA	NA	NA
WP_106221270.1\|932568_934170_-	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	4.8e-87	36.1
WP_106183414.1\|934460_937727_+	DEAD/DEAH box helicase family protein	M1GYP4	Paramecium_bursaria_Chlorella_virus	2.7e-36	27.3
WP_032829049.1\|937996_938431_+	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_010946475.1\|938609_939992_+	replicative DNA helicase	O80281	Escherichia_phage	2.9e-141	58.1
WP_061481418.1\|939993_941067_+	alanine racemase	NA	NA	NA	NA
WP_027223780.1\|941139_941589_+	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_028379495.1\|941757_942192_+	CBS domain-containing protein	NA	NA	NA	NA
WP_106221273.1\|942306_943494_+	hypothetical protein	NA	NA	NA	NA
WP_028379493.1\|943599_943872_+	CDGSH iron-sulfur domain-containing protein	NA	NA	NA	NA
WP_028379492.1\|943891_945442_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.7e-20	37.2
WP_106221275.1\|945593_946583_+	lipoyl synthase	NA	NA	NA	NA
WP_161499055.1\|946924_947503_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_161499056.1\|947430_947778_-\|transposase	transposase	NA	NA	NA	NA
WP_161499057.1\|947830_948163_-\|transposase	transposase	NA	NA	NA	NA
WP_106221284.1\|949345_950854_-	peptide MFS transporter	NA	NA	NA	NA
WP_106142989.1\|950892_951711_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_152027444.1\|952106_953129_+	N,N'-diacetyllegionaminate synthase	A0A1B1IVE2	uncultured_Mediterranean_phage	3.5e-35	38.9
WP_106221289.1\|953128_954262_+	UDP-N-acetylglucosamine 2-epimerase (hydrolyzing)	NA	NA	NA	NA
WP_027268532.1\|954251_954860_+	acetyltransferase	NA	NA	NA	NA
WP_027268531.1\|954870_956373_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_106221291.1\|956462_957026_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.1e-51	57.5
WP_106221293.1\|957026_957911_+	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.2e-31	33.7
WP_192876620.1\|957921_958950_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.7e-83	47.9
WP_106221297.1\|959003_960488_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_161514826.1\|960642_961518_+	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	9.3e-93	58.0
WP_027268525.1\|961538_962495_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_106221301.1\|962478_963483_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_161499056.1\|963796_964144_+\|transposase	transposase	NA	NA	NA	NA
WP_161499055.1\|964071_964650_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_161499058.1\|964993_965572_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_161499056.1\|965499_965847_-\|transposase	transposase	NA	NA	NA	NA
WP_106221305.1\|966082_966361_+\|transposase	transposase	NA	NA	NA	NA
WP_106221307.1\|966347_966830_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_106221309.1\|966924_967650_+	hypothetical protein	NA	NA	NA	NA
WP_106221310.1\|967769_968372_+	hypothetical protein	NA	NA	NA	NA
WP_106221312.1\|968692_969886_-	hypothetical protein	NA	NA	NA	NA
WP_106221314.1\|969995_971951_-	hypothetical protein	NA	NA	NA	NA
WP_106221316.1\|971971_973888_-	hypothetical protein	NA	NA	NA	NA
WP_161499059.1\|973877_975707_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.9e-07	26.8
WP_106221320.1\|975723_976560_-	ABC transporter permease	NA	NA	NA	NA
WP_106221322.1\|976573_977410_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_106221323.1\|977402_978182_-	hypothetical protein	NA	NA	NA	NA
WP_106221325.1\|978223_979534_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_106221327.1\|979546_980551_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_161499060.1\|980551_981319_-	hypothetical protein	NA	NA	NA	NA
WP_106221332.1\|981315_982347_-	N-acetylneuraminate synthase family protein	NA	NA	NA	NA
WP_106221334.1\|982545_983667_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_161499061.1\|983871_984609_+	acylneuraminate cytidylyltransferase family protein	NA	NA	NA	NA
WP_106221338.1\|984628_985714_+	N-acetylneuraminate synthase family protein	NA	NA	NA	NA
WP_106221340.1\|985753_988234_+	hypothetical protein	NA	NA	NA	NA
WP_106221342.1\|988250_989168_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_106221344.1\|989161_990181_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_106221346.1\|990412_991120_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_011213314.1\|991679_991874_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	3.0e-12	70.6
WP_106221348.1\|991965_992961_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_014841197.1\|992964_993702_-	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_010946522.1\|993783_994737_+	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_161514758.1\|994729_996025_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_106221352.1\|996434_996971_+\|transposase	transposase	NA	NA	NA	NA
WP_106221354.1\|997175_998342_+	DUF1574 family protein	NA	NA	NA	NA
WP_106221356.1\|998338_999781_+	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	4.3e-71	40.2
WP_106221358.1\|999886_1001263_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_061504390.1\|1001467_1002169_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_161514759.1\|1002334_1003594_+	MFS transporter	NA	NA	NA	NA
WP_152027445.1\|1003708_1005133_+	hypothetical protein	NA	NA	NA	NA
WP_062727135.1\|1005776_1006163_+	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_106221364.1\|1006337_1007681_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_080464554.1\|1007755_1009552_-	L-aspartate oxidase	NA	NA	NA	NA
WP_062727133.1\|1009548_1010919_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	2.8e-112	49.9
WP_106221366.1\|1011071_1012775_+	sulfate permease	A0A2H4J153	uncultured_Caudovirales_phage	4.2e-41	26.9
WP_106221368.1\|1012947_1014651_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_106221370.1\|1014795_1015794_-	linear amide C-N hydrolase	NA	NA	NA	NA
WP_106221372.1\|1016018_1018406_+	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	9.1e-175	38.4
WP_106194399.1\|1018645_1020085_+	cation:proton antiporter	NA	NA	NA	NA
WP_106194402.1\|1020081_1020924_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_106194405.1\|1020920_1022012_+	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_106221374.1\|1021986_1023402_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_027221169.1\|1023493_1023811_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_011213320.1\|1024006_1025044_+	rod shape-determining protein	NA	NA	NA	NA
WP_027221170.1\|1025021_1025930_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_062740128.1\|1025926_1026406_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_062727124.1\|1026341_1026944_-	pseudouridine synthase	NA	NA	NA	NA
WP_028377915.1\|1027118_1027817_+	hypothetical protein	NA	NA	NA	NA
WP_028377916.1\|1027926_1029183_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.9e-14	74.1
WP_027221175.1\|1029583_1029919_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	5.8e-11	36.5
WP_061481371.1\|1029950_1032218_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	3.0e-167	42.4
WP_062727121.1\|1032444_1033227_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_080464060.1\|1033226_1034477_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_028377920.1\|1034477_1034813_-	hypothetical protein	NA	NA	NA	NA
WP_062727120.1\|1034880_1035480_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA

DBSCAN-SWA_3

1049818 : 1056702

Acinetobacter_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062727111.1\|1049818_1050595_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.1e-57	48.6
WP_062727110.1\|1050587_1051622_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	9.3e-76	47.6
WP_062727109.1\|1051599_1052178_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	3.9e-55	52.6
WP_106221384.1\|1052211_1052937_-	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-17	25.1
WP_106183505.1\|1052933_1053443_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_106183506.1\|1053423_1053993_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_106183507.1\|1053989_1054517_-	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	1.4e-27	47.7
WP_106183508.1\|1054531_1055494_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	5.0e-39	34.4
WP_027227556.1\|1055904_1056702_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-21	33.8

DBSCAN-SWA_4

1401045 : 1406983

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062727573.1\|1401045_1402119_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.5e-28	27.0
WP_062727574.1\|1402103_1402718_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	4.6e-22	38.4
WP_027227759.1\|1402714_1403923_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.9e-98	48.7
WP_106183665.1\|1403930_1404398_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.9e-23	50.9
WP_028378484.1\|1404524_1406162_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.2e-155	52.5
WP_062727576.1\|1406158_1406983_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	2.7e-54	44.3

DBSCAN-SWA_5

2139529 : 2206446

Tupanvirus(18.18%)

integrase,transposase,tRNA,protease

attL 2162138:2162155|attR 2182206:2182223

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106221826.1\|2139529_2141596_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_106221828.1\|2141585_2142491_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_028378051.1\|2142724_2143510_-	DsbA family protein	NA	NA	NA	NA
WP_106221830.1\|2143714_2145880_-	DNA helicase II	A7KV33	Bacillus_phage	9.6e-115	36.9
WP_106183926.1\|2146101_2147061_+	prolyl aminopeptidase	NA	NA	NA	NA
WP_106183927.1\|2147054_2147492_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_028378047.1\|2147694_2148477_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_027227838.1\|2148627_2149587_-	glutathione synthase	NA	NA	NA	NA
WP_106221832.1\|2149586_2150882_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_106184441.1\|2151191_2152088_+	DMT family transporter	NA	NA	NA	NA
WP_027227834.1\|2152091_2152373_+	hypothetical protein	NA	NA	NA	NA
WP_106221836.1\|2152359_2152710_+	sulfurtransferase	NA	NA	NA	NA
WP_106221838.1\|2152743_2153406_-	hypothetical protein	NA	NA	NA	NA
WP_161514725.1\|2153918_2155556_+	alkaline phosphatase family protein	NA	NA	NA	NA
WP_027227830.1\|2155608_2156247_+	uridine kinase	A0A2K9L178	Tupanvirus	1.7e-27	36.7
WP_080463930.1\|2156342_2157149_+	enoyl-ACP reductase	NA	NA	NA	NA
WP_192876614.1\|2157624_2159763_+	hypothetical protein	NA	NA	NA	NA
WP_106221842.1\|2160036_2161911_-	SurA N-terminal domain-containing protein	NA	NA	NA	NA
2162138:2162155	attL	NA	NA	NA	NA
WP_011214112.1\|2162169_2162448_-	HU family DNA-binding protein	B5TA87	Burkholderia_phage	2.5e-15	49.4
WP_027227825.1\|2162576_2165027_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.5e-212	50.6
WP_027227824.1\|2165260_2166535_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	8.4e-135	57.0
WP_010947585.1\|2166678_2167323_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.2e-57	59.5
WP_106221844.1\|2167325_2168657_-	trigger factor	NA	NA	NA	NA
WP_080463929.1\|2169522_2170749_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_106183931.1\|2171066_2172917_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.1e-71	32.8
WP_027227819.1\|2172969_2173644_-	ribonuclease III	A0A0P0BX11	Ostreococcus_lucimarinus_virus	1.3e-25	33.8
WP_027227818.1\|2173633_2174026_-	DUF4845 domain-containing protein	NA	NA	NA	NA
WP_027227817.1\|2174037_2174793_-	signal peptidase I	NA	NA	NA	NA
WP_027227816.1\|2174899_2176732_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	2.1e-22	25.2
WP_161514724.1\|2176926_2177943_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_106183936.1\|2178034_2179174_+	GspL family type II secretion system protein LspL	NA	NA	NA	NA
WP_106183937.1\|2179170_2179641_+	GspM family type II secretion system protein LspM	NA	NA	NA	NA
WP_080463927.1\|2179746_2180280_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_027227811.1\|2180532_2181858_+	deoxyguanosinetriphosphate triphosphohydrolase family protein	NA	NA	NA	NA
WP_106221849.1\|2182542_2184072_+	alpha,alpha-trehalase	NA	NA	NA	NA
2182206:2182223	attR	NA	NA	NA	NA
WP_161514746.1\|2184096_2185161_-	hypothetical protein	NA	NA	NA	NA
WP_106221853.1\|2185252_2185693_-	VOC family protein	NA	NA	NA	NA
WP_010947600.1\|2185926_2186454_+	TIGR00645 family protein	K4K6D8	Caulobacter_phage	1.7e-20	33.8
WP_062727742.1\|2186690_2187911_+	hypothetical protein	NA	NA	NA	NA
WP_062727743.1\|2188034_2189207_+	SET domain-containing protein	NA	NA	NA	NA
WP_062727744.1\|2189545_2189860_+	hypothetical protein	NA	NA	NA	NA
WP_106183941.1\|2190023_2191136_-	hypothetical protein	NA	NA	NA	NA
WP_062727746.1\|2191216_2191492_-	acylphosphatase	NA	NA	NA	NA
WP_062727747.1\|2191644_2191998_+	hypothetical protein	NA	NA	NA	NA
WP_062727748.1\|2192189_2193515_-	phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase family protein	NA	NA	NA	NA
WP_062727749.1\|2193743_2194709_+	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.4e-78	48.3
WP_106221855.1\|2194772_2196494_-	secretion system protein	NA	NA	NA	NA
WP_027222068.1\|2196604_2196871_+	hypothetical protein	NA	NA	NA	NA
WP_161514723.1\|2196915_2197335_+	hypothetical protein	NA	NA	NA	NA
WP_062727752.1\|2197344_2198625_-	MFS transporter	NA	NA	NA	NA
WP_106183942.1\|2199013_2199508_-	hypothetical protein	NA	NA	NA	NA
WP_106221857.1\|2199762_2201043_+	chloride channel protein	NA	NA	NA	NA
WP_161514722.1\|2201142_2201646_+	hypothetical protein	NA	NA	NA	NA
WP_062727420.1\|2201909_2202389_+	YchJ family protein	NA	NA	NA	NA
WP_027227795.1\|2202408_2204214_+	cation:proton antiporter	NA	NA	NA	NA
WP_161499056.1\|2204395_2204743_+\|transposase	transposase	NA	NA	NA	NA
WP_161499058.1\|2204670_2205249_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_161499055.1\|2205592_2206171_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_161499056.1\|2206098_2206446_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2362117 : 2372238

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038838944.1\|2362117_2363806_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	1.0e-15	30.4
WP_161514883.1\|2363937_2364945_-	AraC family transcriptional regulator ligand-binding domain-containing protein	NA	NA	NA	NA
WP_106184006.1\|2365069_2366395_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	6.2e-48	31.4
WP_106221921.1\|2366413_2367562_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.1e-125	58.0
WP_062726357.1\|2367765_2368878_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	7.2e-50	34.7
WP_027229222.1\|2368976_2370116_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.6e-23	26.7
WP_062726356.1\|2370303_2372238_-	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.3e-147	49.6

DBSCAN-SWA_7

2833858 : 2873183

Burkholderia_phage(33.33%)

integrase,transposase

attL 2854805:2854864|attR 2868002:2868065

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_152027460.1\|2833858_2833939_-\|transposase	transposase	NA	NA	NA	NA
WP_014842352.1\|2834447_2835299_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_027265135.1\|2835295_2835904_-	AbiEi antitoxin N-terminal domain-containing protein	NA	NA	NA	NA
WP_014842354.1\|2836146_2836410_+	hypothetical protein	NA	NA	NA	NA
WP_042754800.1\|2836409_2837171_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_014842362.1\|2837578_2838727_+	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_014842363.1\|2838756_2839875_+	DUF3494 domain-containing protein	NA	NA	NA	NA
WP_154080660.1\|2840178_2840337_+	hypothetical protein	NA	NA	NA	NA
WP_027265134.1\|2840384_2840726_+	helix-turn-helix domain-containing protein	A0A218MNC9	uncultured_virus	4.5e-11	39.0
WP_042754799.1\|2840742_2841234_+\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	3.4e-12	26.5
WP_014842364.1\|2841482_2841734_-	hypothetical protein	NA	NA	NA	NA
WP_014842365.1\|2841814_2842009_-	CsbD family protein	NA	NA	NA	NA
WP_014842366.1\|2842141_2842495_-	PRC-barrel domain-containing protein	NA	NA	NA	NA
WP_014842368.1\|2843351_2843855_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014842369.1\|2843857_2845039_-	acetylornithine deacetylase	NA	NA	NA	NA
WP_065211439.1\|2845343_2845511_+	DUF3309 domain-containing protein	NA	NA	NA	NA
WP_014842370.1\|2845635_2846841_+	fatty acid desaturase	NA	NA	NA	NA
WP_014842371.1\|2847047_2848823_-	SLC13 family permease	NA	NA	NA	NA
WP_080031823.1\|2849162_2849597_+	TIGR00341 family protein	NA	NA	NA	NA
WP_014842373.1\|2849632_2849959_+\|transposase	transposase	NA	NA	NA	NA
WP_110540214.1\|2850017_2850458_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_014842375.1\|2850473_2850800_+	DUF389 domain-containing protein	NA	NA	NA	NA
WP_014842376.1\|2851067_2852078_+	fatty acid desaturase	NA	NA	NA	NA
WP_014842377.1\|2852372_2852708_+	hypothetical protein	NA	NA	NA	NA
WP_014842378.1\|2852877_2854209_+	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	3.0e-58	35.6
2854805:2854864	attL	NA	NA	NA	NA
WP_106222062.1\|2855042_2856743_+	AAA family ATPase	E5E3R2	Burkholderia_phage	6.8e-15	22.7
WP_106222064.1\|2856821_2858165_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_152027452.1\|2858674_2859028_-	hypothetical protein	NA	NA	NA	NA
WP_106222072.1\|2859378_2859744_-	TraK family protein	NA	NA	NA	NA
WP_161499066.1\|2859927_2860068_-	hypothetical protein	NA	NA	NA	NA
WP_106222074.1\|2861876_2862152_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_192876615.1\|2862773_2864006_+	DUF4143 domain-containing protein	NA	NA	NA	NA
WP_106222078.1\|2864027_2864795_+	hypothetical protein	NA	NA	NA	NA
WP_106222080.1\|2864960_2865860_+	HipA domain-containing protein	NA	NA	NA	NA
WP_106222082.1\|2865849_2866500_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_106222084.1\|2866612_2867842_-\|integrase	integrase family protein	A0A0P0IKP2	Acinetobacter_phage	8.8e-49	32.4
WP_106222086.1\|2868147_2868504_+	hypothetical protein	NA	NA	NA	NA
2868002:2868065	attR	NA	NA	NA	NA
WP_106222088.1\|2868941_2869976_+	hypothetical protein	NA	NA	NA	NA
WP_062728144.1\|2870158_2871010_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_062728146.1\|2871006_2871615_-	AbiEi antitoxin N-terminal domain-containing protein	NA	NA	NA	NA
WP_106174732.1\|2872007_2873183_-\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	8.3e-12	20.5

DBSCAN-SWA_8

3108674 : 3144543

Acanthamoeba_polyphaga_moumouvirus(20.0%)

integrase,transposase,tRNA

attL 3133756:3133801|attR 3147774:3147819

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027228154.1\|3108674_3109010_-\|tRNA	tRNA-binding protein	NA	NA	NA	NA
WP_080464320.1\|3109087_3109843_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_106184250.1\|3109994_3110579_-	hypothetical protein	NA	NA	NA	NA
WP_062728257.1\|3110881_3111655_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_106222230.1\|3111860_3112856_-	DMT family transporter	NA	NA	NA	NA
WP_062728255.1\|3113280_3114126_+	DUF2306 domain-containing protein	NA	NA	NA	NA
WP_106222232.1\|3114161_3115829_-	lpg2552 family Dot/Icm T4SS effector	NA	NA	NA	NA
WP_106222234.1\|3116006_3117374_+	MFS transporter	NA	NA	NA	NA
WP_106222236.1\|3117513_3119214_-	DnaJ domain-containing protein	L7RC83	Acanthamoeba_polyphaga_moumouvirus	1.2e-08	53.1
WP_027228161.1\|3119790_3120225_+	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	1.0e-15	52.4
WP_062728251.1\|3120391_3120991_+	hypothetical protein	NA	NA	NA	NA
WP_062740188.1\|3121135_3121864_-	hypothetical protein	NA	NA	NA	NA
WP_106184253.1\|3122199_3122874_-	hypothetical protein	NA	NA	NA	NA
WP_152027458.1\|3123238_3123925_-	hypothetical protein	NA	NA	NA	NA
WP_062728225.1\|3124271_3125588_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_106222238.1\|3125789_3127100_-	chromate efflux transporter	A0A219VHC2	Ochrobactrum_phage	9.5e-25	64.7
WP_106222240.1\|3127349_3127979_-\|transposase	transposase	NA	NA	NA	NA
WP_106222244.1\|3128889_3129183_+	hypothetical protein	NA	NA	NA	NA
WP_106222246.1\|3129401_3130457_-	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_192875956.1\|3130453_3131497_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_106222248.1\|3131571_3132606_-	hypothetical protein	NA	NA	NA	NA
WP_106222250.1\|3133391_3133628_-	DUF1653 domain-containing protein	NA	NA	NA	NA
3133756:3133801	attL	NA	NA	NA	NA
WP_080124663.1\|3133970_3135212_+\|integrase	site-specific integrase	I6R9B6	Salmonella_phage	3.5e-45	29.6
WP_106222252.1\|3135709_3136561_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_106222254.1\|3136557_3137145_-	hypothetical protein	NA	NA	NA	NA
WP_027222671.1\|3137401_3137866_+	hypothetical protein	NA	NA	NA	NA
WP_038839570.1\|3139291_3140269_-	Abi family protein	A3QSC6	Clostridium_virus	1.4e-25	27.7
WP_106222256.1\|3140470_3140773_-	hypothetical protein	NA	NA	NA	NA
WP_038839574.1\|3140765_3141398_-	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_106222266.1\|3141404_3142223_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_154213644.1\|3142614_3142767_-	hypothetical protein	NA	NA	NA	NA
WP_106222268.1\|3142847_3143657_+\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_106222270.1\|3143646_3144543_+\|integrase	integrase domain-containing protein	NA	NA	NA	NA
3147774:3147819	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP021256

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection