CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021267	Legionella pneumophila subsp. pneumophila strain Burlington 1 (D-7841) chromosome, complete genome	0 crisprs	RT,PD-DExK,DEDDh,DinG,cas3,WYL,csa3	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

922906 : 929746

Acinetobacter_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010946569.1\|922906_923683_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.3e-57	48.2
WP_010946570.1\|923675_924710_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	3.5e-75	47.6
WP_010946571.1\|924687_925266_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.0e-55	53.2
WP_010946572.1\|925299_926025_-	LPS export ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.1e-17	28.3
WP_010946573.1\|926021_926531_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_010946574.1\|926511_927081_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_011213328.1\|927077_927605_-	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	1.4e-27	47.7
WP_010946576.1\|927618_928581_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	4.2e-38	34.1
WP_010946577.1\|928948_929746_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.3e-21	33.8

DBSCAN-SWA_2

1312127 : 1318064

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010946911.1\|1312127_1313201_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.8e-30	27.8
WP_010946912.1\|1313185_1313800_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	3.5e-22	38.4
WP_010946913.1\|1313796_1315005_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.4e-99	48.7
WP_010946914.1\|1315012_1315480_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	9.2e-23	49.1
WP_010946915.1\|1315605_1317243_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.6e-154	52.3
WP_010946916.1\|1317239_1318064_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.8e-53	43.9

DBSCAN-SWA_3

2221602 : 2231726

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010947735.1\|2221602_2223291_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	8.0e-16	30.4
WP_015444337.1\|2223422_2224430_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_010947737.1\|2224553_2225879_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	1.4e-47	31.2
WP_010947738.1\|2225897_2227046_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-126	58.5
WP_015444336.1\|2227254_2228367_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	2.9e-51	35.2
WP_010947740.1\|2228462_2229602_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.6e-23	26.9
WP_015444335.1\|2229791_2231726_-	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.3e-147	49.6

DBSCAN-SWA_4

2273554 : 2328579

Wolbachia_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010947782.1\|2273554_2275006_+\|transposase	IS4-like element ISLpn5 family transposase	Q9JMP3	Wolbachia_phage	6.1e-158	56.8
WP_010947783.1\|2275076_2276597_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	7.9e-124	48.2
WP_010947785.1\|2277444_2277819_+	hypothetical protein	NA	NA	NA	NA
WP_010947786.1\|2278016_2279624_-	hypothetical protein	NA	NA	NA	NA
WP_015444248.1\|2279626_2280118_-	hypothetical protein	NA	NA	NA	NA
WP_010947788.1\|2280128_2280965_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S6L1V5	Vibrio_phage	4.9e-67	48.9
WP_010947789.1\|2281557_2282649_-	DUF4917 family protein	NA	NA	NA	NA
WP_010947790.1\|2282880_2288826_-	conjugative transfer relaxase/helicase TraI	NA	NA	NA	NA
WP_010947791.1\|2288846_2290739_-	type IV conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_021437030.1\|2290803_2291268_+	hypothetical protein	NA	NA	NA	NA
WP_015444244.1\|2291271_2293992_-	conjugal transfer protein TraG N-terminal domain-containing protein	NA	NA	NA	NA
WP_010947793.1\|2293997_2295383_-	conjugal transfer protein TraH	NA	NA	NA	NA
WP_010947794.1\|2295379_2295802_-	type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB	NA	NA	NA	NA
WP_010947795.1\|2295791_2296574_-	type-F conjugative transfer system pilin assembly protein TraF	NA	NA	NA	NA
WP_010947796.1\|2296566_2298378_-	type-F conjugative transfer system mating-pair stabilization protein TraN	NA	NA	NA	NA
WP_015444243.1\|2298377_2299046_-	type-F conjugative transfer system pilin assembly protein TrbC	NA	NA	NA	NA
WP_010947798.1\|2299061_2300057_-	TraU family protein	NA	NA	NA	NA
WP_010947799.1\|2300053_2300662_-	type-F conjugative transfer system protein TraW	NA	NA	NA	NA
WP_015444242.1\|2300658_2300994_-	TrbI F-type domain-containing protein	NA	NA	NA	NA
WP_015444241.1\|2300986_2303539_-	type IV secretion system protein TraC	NA	NA	NA	NA
WP_010947801.1\|2303550_2303901_-	type IV conjugative transfer system lipoprotein TraV	NA	NA	NA	NA
WP_015444240.1\|2303914_2305201_-	TraB/VirB10 family protein	NA	NA	NA	NA
WP_010947803.1\|2305202_2305916_-	type-F conjugative transfer system secretin TraK	NA	NA	NA	NA
WP_010947804.1\|2305918_2306482_-	type IV conjugative transfer system protein TraE	NA	NA	NA	NA
WP_010947805.1\|2306485_2306779_-	type IV conjugative transfer system protein TraL	NA	NA	NA	NA
WP_010947806.1\|2306780_2307083_-	fimbrial protein	NA	NA	NA	NA
WP_010947807.1\|2307097_2307334_-	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	2.5e-08	52.9
WP_025520140.1\|2307347_2307725_-	hypothetical protein	NA	NA	NA	NA
WP_010947808.1\|2307672_2308557_-	hypothetical protein	NA	NA	NA	NA
WP_015444237.1\|2308729_2309410_+	helix-turn-helix domain-containing protein	A0A1I9KG86	Aeromonas_phage	1.6e-07	28.1
WP_016356978.1\|2309558_2310233_+\|transposase	transposase	NA	NA	NA	NA
WP_010947811.1\|2310681_2311254_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_015444236.1\|2311237_2311735_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_010947813.1\|2311727_2312315_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_010947814.1\|2312319_2314455_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_010947815.1\|2314473_2315355_-	sterol desaturase family protein	NA	NA	NA	NA
WP_010947816.1\|2315461_2315608_-	hypothetical protein	NA	NA	NA	NA
WP_010947817.1\|2315799_2315976_+	MAPEG family protein	NA	NA	NA	NA
WP_010947818.1\|2316145_2316643_-	DoxX family protein	NA	NA	NA	NA
WP_010947819.1\|2316632_2317412_-	DUF2063 domain-containing protein	NA	NA	NA	NA
WP_010947820.1\|2317404_2318259_-	DUF692 domain-containing protein	NA	NA	NA	NA
WP_010947821.1\|2318273_2318567_-	DUF2282 domain-containing protein	NA	NA	NA	NA
WP_010947822.1\|2318756_2319278_-	hypothetical protein	NA	NA	NA	NA
WP_015444234.1\|2319582_2320041_-	hypothetical protein	NA	NA	NA	NA
WP_015444232.1\|2320614_2320842_-	hypothetical protein	NA	NA	NA	NA
WP_010947824.1\|2320999_2321521_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_010947825.1\|2321692_2322247_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_010947826.1\|2322680_2322881_+	ATP-dependent DNA helicase	NA	NA	NA	NA
WP_010947827.1\|2322974_2323358_+\|transposase	transposase	NA	NA	NA	NA
WP_010947828.1\|2323411_2324365_-	Abi family protein	A3QSC6	Clostridium_virus	4.8e-34	31.8
WP_015444229.1\|2324874_2326293_+\|transposase	IS4-like element ISLpn3 family transposase	Q9JMP3	Wolbachia_phage	2.3e-56	32.9
WP_010947829.1\|2326325_2327501_-\|transposase	ISL3 family transposase	A4PE56	Ralstonia_virus	5.2e-14	21.2
WP_010947830.1\|2327553_2328579_-\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

2625729 : 2688998

Erysipelothrix_phage(18.75%)

protease,integrase,tRNA,transposase

attL 2631637:2631683|attR 2687669:2687715

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010948063.1\|2625729_2626731_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	5.8e-91	50.7
WP_010948064.1\|2626935_2627175_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_010948065.1\|2627377_2627821_+	lpg2359 family Dot/Icm T4SS effector	A0A292GL36	Xanthomonas_phage	6.3e-21	43.8
WP_014842314.1\|2627829_2629563_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-59	35.5
WP_011216252.1\|2629649_2631515_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.3e-35	32.8
2631637:2631683	attL	NA	NA	NA	NA
WP_187297743.1\|2631773_2632901_-\|integrase	site-specific integrase	A0A059VF45	Pseudomonas_phage	2.2e-86	47.3
WP_061466610.1\|2633281_2633467_+	hypothetical protein	NA	NA	NA	NA
WP_061466612.1\|2633459_2634236_+	methylase	NA	NA	NA	NA
WP_061634671.1\|2634369_2635185_+	hypothetical protein	NA	NA	NA	NA
WP_061466974.1\|2635226_2636537_-	hypothetical protein	NA	NA	NA	NA
WP_061466975.1\|2636666_2638148_+	MFS transporter	A0A0P0IY73	Acinetobacter_phage	9.4e-29	24.8
WP_061466976.1\|2638301_2638544_+	hypothetical protein	NA	NA	NA	NA
WP_061466977.1\|2638778_2638973_+	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	4.8e-18	60.3
WP_061634672.1\|2639000_2642276_+	DEAD/DEAH box helicase family protein	A0A2K5B2B9	Erysipelothrix_phage	4.8e-235	42.8
WP_061466985.1\|2642268_2642931_+	DUF4391 domain-containing protein	NA	NA	NA	NA
WP_061634673.1\|2642950_2644906_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	2.0e-103	36.1
WP_061466981.1\|2644923_2647956_+	DEAD/DEAH box helicase family protein	A0A2K5B2C2	Erysipelothrix_phage	1.7e-130	33.4
WP_061634674.1\|2648031_2649831_+	DUF4209 domain-containing protein	NA	NA	NA	NA
WP_061466952.1\|2649827_2650511_-	helix-turn-helix domain-containing protein	A0A1I9KG86	Aeromonas_phage	6.5e-17	33.3
WP_061466938.1\|2650712_2651597_+	hypothetical protein	NA	NA	NA	NA
WP_042234550.1\|2651616_2651928_+	Vir protein	NA	NA	NA	NA
WP_042234461.1\|2651944_2652217_+	carbon storage regulator	A0A0U1UNS3	Pseudomonas_phage	5.0e-05	41.8
WP_042234463.1\|2652244_2653210_+	P-type conjugative transfer ATPase TrbB	NA	NA	NA	NA
WP_042234466.1\|2653221_2653599_+	TrbC/VirB2 family protein	NA	NA	NA	NA
WP_061466939.1\|2653595_2653895_+	VirB3 family type IV secretion system protein	NA	NA	NA	NA
WP_061466940.1\|2653891_2656426_+	conjugal transfer protein TrbE	NA	NA	NA	NA
WP_061466941.1\|2656422_2657121_+	conjugal transfer protein TrbF	NA	NA	NA	NA
WP_061466942.1\|2657117_2657993_+	P-type conjugative transfer protein TrbG	NA	NA	NA	NA
WP_061466943.1\|2657995_2658403_+	conjugal transfer protein TrbH	NA	NA	NA	NA
WP_061466944.1\|2658408_2659656_+	TrbI/VirB10 family protein	NA	NA	NA	NA
WP_061466945.1\|2659667_2660408_+	P-type conjugative transfer protein TrbJ	NA	NA	NA	NA
WP_061466946.1\|2660430_2660643_+	hypothetical protein	NA	NA	NA	NA
WP_061466947.1\|2660647_2662030_+	P-type conjugative transfer protein TrbL	NA	NA	NA	NA
WP_061466948.1\|2662026_2663916_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_061466949.1\|2663912_2664458_+	conjugative transfer signal peptidase TraF	NA	NA	NA	NA
WP_187297749.1\|2664454_2664619_+	hypothetical protein	NA	NA	NA	NA
WP_061466950.1\|2664611_2666798_+	DUF1738 domain-containing protein	A0A1B1IRD0	uncultured_Mediterranean_phage	1.1e-36	33.9
WP_061634675.1\|2666927_2668523_-	hypothetical protein	NA	NA	NA	NA
WP_061466916.1\|2668832_2670695_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_058450394.1\|2670691_2671045_-	conjugal transfer transcriptional regulator TraJ	NA	NA	NA	NA
WP_058450393.1\|2671438_2671783_+	TraK family protein	NA	NA	NA	NA
WP_058450392.1\|2671782_2672508_+	conjugal transfer protein TraL	NA	NA	NA	NA
WP_061466918.1\|2672507_2672945_+	conjugal transfer protein TraM	NA	NA	NA	NA
WP_061466920.1\|2673192_2674254_-	DUF4116 domain-containing protein	NA	NA	NA	NA
WP_080444600.1\|2674676_2676311_+\|transposase	transposase	NA	NA	NA	NA
WP_040146985.1\|2676265_2676658_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_058450390.1\|2677139_2677382_-	hypothetical protein	NA	NA	NA	NA
WP_061466923.1\|2677624_2679565_+	DUF2779 domain-containing protein	NA	NA	NA	NA
WP_044496813.1\|2679644_2680496_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_044496821.1\|2680492_2681101_-	AbiEi antitoxin N-terminal domain-containing protein	NA	NA	NA	NA
WP_058450388.1\|2681908_2682313_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.1e-08	33.1
WP_080444601.1\|2682270_2682396_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_044496812.1\|2682520_2683573_+	LD-carboxypeptidase	NA	NA	NA	NA
WP_161499102.1\|2683579_2684743_-	MFS transporter	NA	NA	NA	NA
WP_052585449.1\|2684826_2685873_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	1.5e-25	32.4
WP_061466927.1\|2685874_2686939_-	ThiF family adenylyltransferase	NA	NA	NA	NA
WP_015444121.1\|2687822_2688998_-\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	3.8e-17	23.2
2687669:2687715	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage