CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NZ_CP043621	Rhodobacteraceae bacterium SH-1 plasmid p3, complete sequence	0 crisprs	NA	1
NZ_CP043623	Rhodobacteraceae bacterium SH-1 plasmid p5, complete sequence	0 crisprs	NA	0
NZ_CP043620	Rhodobacteraceae bacterium SH-1 plasmid p2, complete sequence	0 crisprs	PrimPol	7
NZ_CP043619	Rhodobacteraceae bacterium SH-1 plasmid p1, complete sequence	0 crisprs	PrimPol	1
NZ_CP043622	Rhodobacteraceae bacterium SH-1 plasmid p4, complete sequence	0 crisprs	NA	3
NZ_CP027665	Rhodobacteraceae bacterium SH-1 chromosome, complete genome	4 crisprs	csa3,WYL,DEDDh	278

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5580 : 43346

uncultured_Caudovirales_phage(11.11%)

integrase,transposase

attL 31188:31203|attR 39018:39033

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615737.1\|5580_6678_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149615738.1\|6834_7614_+	DUF1403 family protein	NA	NA	NA	NA
WP_149615585.1\|7859_9377_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2H4JGQ6	uncultured_Caudovirales_phage	1.1e-11	22.7
WP_149615584.1\|9345_10209_+	AAA family ATPase	NA	NA	NA	NA
WP_149615583.1\|10172_11168_+	hypothetical protein	NA	NA	NA	NA
WP_149615739.1\|12166_13030_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_149615740.1\|13026_13854_-	hypothetical protein	NA	NA	NA	NA
WP_149615741.1\|14152_15331_+	DNA repair exonuclease	NA	NA	NA	NA
WP_149615742.1\|15327_18735_+	AAA family ATPase	NA	NA	NA	NA
WP_149615743.1\|18993_20103_+	hypothetical protein	NA	NA	NA	NA
WP_149615789.1\|20358_20529_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_149615744.1\|20666_21395_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.3e-33	34.6
WP_149615745.1\|21327_22893_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	4.6e-18	28.5
WP_149615746.1\|22985_23288_-	hypothetical protein	NA	NA	NA	NA
WP_149615747.1\|23265_24222_-	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_149615748.1\|24243_24879_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_149615749.1\|24951_25494_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_149615750.1\|25523_25886_-	hypothetical protein	NA	NA	NA	NA
WP_149615751.1\|26021_26975_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149615752.1\|27132_27642_+	DUF4142 domain-containing protein	NA	NA	NA	NA
WP_149615753.1\|27629_27995_+	copper-binding protein	NA	NA	NA	NA
WP_149615754.1\|28064_28757_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_149615790.1\|28891_29302_+	hypothetical protein	NA	NA	NA	NA
WP_149615755.1\|29784_30459_+	DUF1738 domain-containing protein	A0A1V0EEV1	Caulobacter_phage	4.9e-25	39.5
WP_149615756.1\|30502_31501_-\|integrase	tyrosine-type recombinase/integrase	A0A2K9VH72	Gordonia_phage	5.6e-17	28.0
31188:31203	attL	NA	NA	NA	NA
WP_149615757.1\|31497_32442_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149615791.1\|32438_33500_-\|integrase	tyrosine-type recombinase/integrase	A0A1L4BKH1	Thermus_phage	9.1e-10	29.3
WP_149615758.1\|33782_35486_+	hypothetical protein	Q7Y5U5	Haemophilus_phage	6.4e-05	25.0
WP_114276310.1\|35482_35977_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_149615759.1\|36442_36655_+	hypothetical protein	NA	NA	NA	NA
WP_149615760.1\|36742_37132_+	DUF3768 domain-containing protein	NA	NA	NA	NA
WP_149615761.1\|37276_39250_+	ParB N-terminal domain-containing protein	A0A0F7L836	uncultured_marine_virus	6.0e-07	36.4
39018:39033	attR	NA	NA	NA	NA
WP_149615762.1\|39318_39912_+	regulator	NA	NA	NA	NA
WP_149615763.1\|40115_40772_+	hypothetical protein	NA	NA	NA	NA
WP_149615764.1\|40856_41099_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_149615765.1\|41088_41508_+	hypothetical protein	NA	NA	NA	NA
WP_149615766.1\|42635_43346_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	3.8e-28	34.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP043622

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 4582

Aurantimonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615795.1\|2579_3479_-	RepB family plasmid replication initiator protein	NA	NA	NA	NA
WP_149615796.1\|3549_3894_-	stability/partitioning determinant	NA	NA	NA	NA
WP_149615797.1\|3895_4582_-	AAA family ATPase	A0A0A8IL09	Aurantimonas_phage	8.2e-44	43.6

DBSCAN-SWA_2

10305 : 20110

Burkholderia_virus(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615824.1\|10305_11859_+\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	4.8e-07	27.0
WP_149615825.1\|13380_13986_-	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	1.4e-18	33.8
WP_149615805.1\|14080_16969_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	2.3e-180	36.8
WP_149615806.1\|17205_18105_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_149615807.1\|18132_19128_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	8.5e-18	32.5
WP_149615808.1\|19117_20110_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	2.9e-10	29.7

DBSCAN-SWA_3

33909 : 37513

Salmonella_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615820.1\|33909_36813_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	2.1e-186	38.7
WP_149615821.1\|36907_37513_+	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	8.8e-18	33.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP027665

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP027665_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027665_1

1566638-1566938

Orphan

Consensus_repeat	Method
GCGGCAAGGTCACCTATCCCGACGG	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_CP027665_1

>merge|NZ_CP027665|1|1566638-1566938|CRISPRCasFinder
GCGGCAAGGTCACCTATCCCGACGGGTCGTTCTATACCGGCCAGTTCCTCGACGATCTGGCCCACGGGCGCGGCAAGATCACCTATCCCGACGGCGCCACCTATGACGGCGACTGGGTGAACGGGGTGATCGAGGGCAACGGCGTGGCCACCTATCCCGGCGGGGTCGTCTATGACGGCGAGTTTCGCAATGCGCGCAACCACGGCCGGGGCGTGATGACCTATCCCGACGGGTATCGCTATGACGGCGACTGGAAGGACGGCAAGCGCAGCGGACAGGGCAAGGCCACCTATGCCGATGG

>NZ_CP027665|1|1|1566638-1566938|CRISPRCasFinder
GCGGCAAGGTCACCTATCCCGACGG	GTCGTTCTATACCGGCCAGTTCCTCGACGATCTGGCCCACGGGC
GCGGCAAGATCACCTATCCCGACGG	CGCCACCTATGACGGCGACTGGGTGAACGGGGTGATCGAGGGCA
ACGGCGTGGCCACCTATCCCGGCGG	GGTCGTCTATGACGGCGAGTTTCGCAATGCGCGCAACCACGGCC
GGGGCGTGATGACCTATCCCGACGG	GTATCGCTATGACGGCGACTGGAAGGACGGCAAGCGCAGCGGAC
AGGGCAAGGCCACCTATGCCGATGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027665.1\|WP_106471948.1\|1573730_1574870_+\|rod-shape-determining-protein-RodA	unknown	unknown	gnl\|CDD\|274033
NZ_CP027665.1\|WP_106471934.1\|1555970_1556624_-\|arylesterase	unknown	unknown	gnl\|CDD\|238860
NZ_CP027665.1\|WP_106474007.1\|1571251_1571794_+\|rod-shape-determining-protein-MreD	unknown	unknown	unknown
NZ_CP027665.1\|WP_106471945.1\|1569241_1570288_+\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237562
NZ_CP027665.1\|WP_106471936.1\|1557326_1559855_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|225669
NZ_CP027665.1\|WP_106471944.1\|1567479_1569054_+\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|234864
NZ_CP027665.1\|WP_106471949.1\|1574877_1575810_+\|glyoxylate/hydroxypyruvate-reductase-A	unknown	unknown	gnl\|CDD\|240641
NZ_CP027665.1\|WP_106471938.1\|1560410_1560983_+\|gamma-glutamylcyclotransferase	unknown	unknown	gnl\|CDD\|119400
NZ_CP027665.1\|WP_106471952.1\|1578186_1579230_-\|HesA/MoeB/ThiF-family-protein	unknown	unknown	gnl\|CDD\|238386
NZ_CP027665.1\|WP_106471933.1\|1555403_1555961_+\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|224294
NZ_CP027665.1\|WP_106471939.1\|1561058_1562384_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|183594
NZ_CP027665.1\|WP_106471940.1\|1562449_1562878_-\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|378058
NZ_CP027665.1\|WP_106471937.1\|1559862_1560309_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP027665.1\|WP_106471946.1\|1570347_1571259_+\|rod-shape-determining-protein-MreC	unknown	unknown	gnl\|CDD\|237560
NZ_CP027665.1\|WP_106471941.1\|1562988_1563912_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293806
NZ_CP027665.1\|WP_106471947.1\|1571790_1573734_+\|penicillin-binding-protein-2	unknown	unknown	gnl\|CDD\|274573
NZ_CP027665.1\|WP_106471942.1\|1563924_1565583_-\|NAD+-synthase	unknown	unknown	gnl\|CDD\|237577
NZ_CP027665.1\|WP_106471935.1\|1556616_1557330_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226647
NZ_CP027665.1\|WP_106471951.1\|1576168_1578184_-\|M3-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341051
NZ_CP027665.1\|WP_106471950.1\|1575803_1576172_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225197

Protein	Function_ID	Function_description	E-value
NZ_CP027665.1\|WP_106471948.1\|1573730_1574870_+\|rod-shape-determining-protein-RodA	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	6.40515e-161
NZ_CP027665.1\|WP_106471934.1\|1555970_1556624_-\|arylesterase	gnl\|CDD\|238860	cd01822, Lysophospholipase_L1_like, Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity.	4.42873e-76
NZ_CP027665.1\|WP_106471945.1\|1569241_1570288_+\|rod-shape-determining-protein	gnl\|CDD\|237562	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional.	0
NZ_CP027665.1\|WP_106471936.1\|1557326_1559855_+\|FtsX-like-permease-family-protein	gnl\|CDD\|225669	COG3127, COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP027665.1\|WP_106471944.1\|1567479_1569054_+\|2-isopropylmalate-synthase	gnl\|CDD\|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NZ_CP027665.1\|WP_106471949.1\|1574877_1575810_+\|glyoxylate/hydroxypyruvate-reductase-A	gnl\|CDD\|240641	cd12164, GDH_like_2, Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family. This group contains a variety of proteins variously identified as glycerate dehydrogenase (GDH, also known as hydroxypyruvate reductase) and other enzymes of the 2-hydroxyacid dehydrogenase family. GDH catalyzes the reversible reaction of (R)-glycerate + NAD+ to hydroxypyruvate + NADH + H+. 2-hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.34646e-136
NZ_CP027665.1\|WP_106471938.1\|1560410_1560983_+\|gamma-glutamylcyclotransferase	gnl\|CDD\|119400	cd06661, GGCT_like, GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is encoded by the gene C7orf24, and the enzyme participates in the gamma-glutamyl cycle. Hereditary defects in the gamma-glutamyl cycle have been described for some of the genes involved, but not for C7orf24. The synthesis and metabolism of glutathione (L-gamma-glutamyl-L-cysteinylglycine) ties the gamma-glutamyl cycle to numerous cellular processes; glutathione acts as a ubiquitous reducing agent in reductive mechanisms involved in protein and DNA synthesis, transport processes, enzyme activity, and metabolism. AIG2 (avrRpt2-induced gene) is an Arabidopsis protein that exhibits RPS2- and avrRpt2-dependent induction early after infection with Pseudomonas syringae pv maculicola strain ES4326 carrying avrRpt2. avrRpt2 is an avirulence gene that can convert virulent strains of P. syringae to avirulence on Arabidopsis thaliana, soybean, and bean. The family also includes bacterial tellurite-resistance proteins (trgB); tellurium (Te) compounds are used in industrial processes and had been used as antimicrobial agents in the past. Some members have been described proteins involved in cation transport (chaC).	1.72778e-10
NZ_CP027665.1\|WP_106471952.1\|1578186_1579230_-\|HesA/MoeB/ThiF-family-protein	gnl\|CDD\|238386	cd00757, ThiF_MoeB_HesA_family, ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD and ThiS, respectively, on the alpha-phosphate of an ATP molecule bound at the active site of the activating enzymes, leading to the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD and ThiS. MoeB, as the MPT synthase (MoaE/MoaD complex) sulfurase, is involved in the biosynthesis of the molybdenum cofactor, a derivative of the tricyclic pterin, molybdopterin (MPT). ThiF catalyzes the adenylation of ThiS, as part of the biosynthesis pathway of thiamin pyrophosphate (vitamin B1). .	3.3279e-114
NZ_CP027665.1\|WP_106471933.1\|1555403_1555961_+\|L,D-transpeptidase	gnl\|CDD\|224294	COG1376, ErfK, Uncharacterized protein conserved in bacteria [Function unknown].	4.84698e-38
NZ_CP027665.1\|WP_106471939.1\|1561058_1562384_-\|glutamate--tRNA-ligase	gnl\|CDD\|183594	PRK12558, PRK12558, glutamyl-tRNA synthetase; Provisional.	0
NZ_CP027665.1\|WP_106471940.1\|1562449_1562878_-\|DUF1801-domain-containing-protein	gnl\|CDD\|378058	pfam08818, DUF1801, Domain of unknown function (DU1801). This large family of bacterial proteins is uncharacterized. They contain a presumed domain about 110 amino acids in length.	3.67502e-19
NZ_CP027665.1\|WP_106471937.1\|1559862_1560309_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	9.47136e-39
NZ_CP027665.1\|WP_106471946.1\|1570347_1571259_+\|rod-shape-determining-protein-MreC	gnl\|CDD\|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	2.09088e-72
NZ_CP027665.1\|WP_106471941.1\|1562988_1563912_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293806	cd07720, OPHC2-like_MBL-fold, Pseudomonas pseudoalcaligenes organophosphorus hydrolase C2, and related proteins; MBL-fold metallo hydrolase domain. Pseudomonas pseudoalcaligenes OPHC2 is a thermostable organophosphorus hydrolase which a broad substrate activity spectrum: it hydrolyzes various phosphotriesters, esters, and a lactone. This subgroup also includes Pseudomonas oleovorans PoOPH which exhibits high lactonase and esterase activities, and latent PTE activity. However, double mutations His250Ile/Ile263Trp switch PoOPH into an efficient and thermostable PTE. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.78684e-85
NZ_CP027665.1\|WP_106471947.1\|1571790_1573734_+\|penicillin-binding-protein-2	gnl\|CDD\|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP027665.1\|WP_106471942.1\|1563924_1565583_-\|NAD+-synthase	gnl\|CDD\|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0
NZ_CP027665.1\|WP_106471935.1\|1556616_1557330_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226647	COG4181, COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism].	1.41659e-101
NZ_CP027665.1\|WP_106471951.1\|1576168_1578184_-\|M3-family-metallopeptidase	gnl\|CDD\|341051	cd06456, M3A_DCP, Peptidase family M3, dipeptidyl carboxypeptidase (DCP). Peptidase family M3 dipeptidyl carboxypeptidase (DCP; Dcp II; peptidyl dipeptidase; EC 3.4.15.5). This metal-binding M3A family also includes oligopeptidase A (OpdA; EC 3.4.24.70). DCP cleaves dipeptides off the C-termini of various peptides and proteins, the smallest substrate being N-blocked tripeptides and unblocked tetrapeptides. DCP from Escherichia coli is inhibited by the anti-hypertensive drug captopril, an inhibitor of the mammalian angiotensin converting enzyme (ACE, also called peptidyl dipeptidase A). OpdA may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. It can also cleave N-acetyl-L-Ala. This family also includes Arabidopsis thaliana organellar oligopeptidase OOP (At5g65620), which plays a role in targeting peptide degradation in mitochondria and chloroplasts; it degrades peptide substrates that are between 8 to 23 amino acid residues, and shows a weak preference for hydrophobic residues (F/L) at the P1 position.	0
NZ_CP027665.1\|WP_106471950.1\|1575803_1576172_-\|hypothetical-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	4.92707e-27

>NZ_CP027665.1|WP_106471942.1|1563924_1565583_-|NAD+-synthase
MADRFRVTLAQLNPVVGDLDGNAAKARQAWEQGRDAGADLVALPEMFITGYNTQDLVMKPAFHTAAIERVRALAAECADGPALAIGAPWVEGTSLYNAYLICKGGRIVATPLKHHLPNETVFDEMRIFDAGPLGGPYVVGGVRIGSPICEDAWHDDVAETLAETGAEFLLVPNGSPYYRDKFEVRLNHMVARVVETGLPVIYLNMVGGQDDQVFDGGTFALNPGGELALQMPLFDEAIAQVDLERTPEGWRLIGGEEHVHPDAWEQDYRVMVTGLRDYLAKSGFAKVLLGLSGGVDSALVAAIAADALGPENVRCVMLPSEYTSPESLEDAEAVAKALGCGYDHVPISEGRAAITRTLAPLFEGLEPGLTEENIQSRLRGLLLMALSNKFGEMLLTTGNKSEVAVGYATIYGDMAGGYNPLKDLYKTRVFETCRWRNANHRDWMMGPVGQVIPPRVIDKPPSAELREDQKDSDSLPDYAELDAMLEILVDRDGSIADCVASGFDREVARRVERLIYLSEYKRFQSAPGPRLTKGAFWLDRRYPIVNRWRDPS
>NZ_CP027665.1|WP_106471941.1|1562988_1563912_+|MBL-fold-metallo-hydrolase
MTSPKLTRRAALTGAAALAGAAAATGRAQAGAPMSSGRNAPYYRFKLGEFEVTTILAGSRSVDDPQTIFGMNAPAEEFAAASAAAHIPADRTRFFFTPTLVNTGPELILFDTGLNAAATTAALAAAGYAPDQVDTVVITHMHGDHIGGMMKDGAPTYANARVLTGQVEFDAWAGMENETFEAQMRPVAERTEFLNDGGSVVSGITAMAAFGHTPGHMTYMLESGGKQLLLMADLANHYVWSLAYPDWEVRFDMDKSAAAASRRKVLGMLAADGIPLIGYHMPFPALGFVDTRDDGFHYVPHGYQMML
>NZ_CP027665.1|WP_106471940.1|1562449_1562878_-|DUF1801-domain-containing-protein
MAGNKTVPTGADVAGFFDAVTPPRRAADARALDALFRRVTGFTPVMWGPSIVGYGRYHYRHDSGREGDFLATGFSPRKASLVIYIMPGYFGFPDILPRLGKHRSGKSCLYINTLADVDETVLEDLVAAGLARLRDIWPVMPA
>NZ_CP027665.1|WP_106471939.1|1561058_1562384_-|glutamate--tRNA-ligase
MTTTRFAPSPTGYLHVGNLRTALMNWLIARKAGGTFILRIDDTDPERSKEEYVDAIKQDLEWLGLHWDRVERQSERLDRYAEAADRLRGMGRFYEAFETPTELDLKRKKLLNMGRPPVYDRAALSLSEDEKAALRAERGNGVWRFKLDQERIEWPDGILGDVSIDAASVSDPVLIRGDGQVLYTLASVVDDTEMGVTDVVRGADHVTNTATQIQIIAALGGNCPRFAHHSLLTGPQGEALSKRLGVLALRDLRAAGVQPMALLSQMARLGSADPVELRSDMAALVDGFDVTRFGTAPTKFDVEDLYPLTARHLQALPLEAVAVDVAALGVPDELAPAFWAVARDNITTLGDLGEWWALCRDGAEPLIDEGDAEFVAKAIALLPEGPFDETSWASWTQAVKGATGRKGKGLFMPLRKALTGREHGPDMSALMPLLQVIRARS
>NZ_CP027665.1|WP_106471938.1|1560410_1560983_+|gamma-glutamylcyclotransferase
MSDPHFFGYGSLVNRATHAYPDLHRARLRGWRRAWAQTSLRSVAFLTIVPADPQAEIDGLTARVPGSDWAALDAREWAYDRITVTAEVTHPAPHPREIAVYSVPPRHRNAPGGDHPILLSYLDVVVQGYLREFGEPGAARFFASTDGWQAPVLDDRAAPRYPRHQRLTEAETALVDDLLGTCGATIITAA
>NZ_CP027665.1|WP_106471937.1|1559862_1560309_-|Rrf2-family-transcriptional-regulator
MRITKRTNIAVRLLMYCAVNDDRLVTKAEIASCCNISENHLAQVINQLAQLGYLNTQRGRNGGMSLAHAAREIRIGDVFRDVEGDLPVVECFADADNTCPLTDVCRLKLALADAAQAFFMALDEVTLDALVCDNGDLVRMLQPVVCAR
>NZ_CP027665.1|WP_106471936.1|1557326_1559855_+|FtsX-like-permease-family-protein
MSLPMAARLARRELRGGLRGFRILLACLTLGVAAIAAVGSTRSAIHAGLVRDGAVLLGGDAEMSFTYRRASDAERDWMRRHATAISEVIDFRSMAVAGSGDAADRALTQVKAVDDAYPLTGRVALSPEMTLAQALAGRDGLPGVVMERGLVERLGLSPGDRLRFGTRDFVLTATLTGEPDGAAAGFALAPRSIVASAALETSGLLAPGTLFSSHYRLLLPDGAALAPLADAARAAFRDSGLRWRDARNGAPGVARFVDRLGAFLVLVGLSGLAVGGIGVSAAVRAYLAGKTDTIATLRTLGADRFTVFASYFLQVGLLSGLGVVLGLVLGGALPLALSPLIAARLPVPAVFAVYPLPLAEAAIYGMLTALIFTLWPLARTEEVRAATLFRDALSAGRVLPRPRYLLLALAALALLLALAAGFSGRRWLTLWTAGGIIGTLAALSLAALAIRGLARRGASGARGRPALRWALAAIGGPREQAMSVVLSLGLGLSVLAAVSQIDGNLRRAITGNLPDIAPSFFFVDIQRDQMPGFTARLDAAPSVSRVDSAPMLRGVITRINGRPAQEVAGNHWVLRGDRGVTYADAPPPGTTITEGTWWPPGYSGPPRVSFAAEEAAEMGLRLGDRITVNILGRDITATITSFREVDFSTAGMGFVLSMNPAALAGAPHSFIATVYAEASGEATILRDLAGAYPNITAIRVRDAIDRVSGVLAGLASATSLGAAVTLVTGFLVLIGAGAAGEAARAYEAAILKTLGATRGRILASFALRAAILGAAAGLVALAAGIAGGWAVSRFVFETRFTVVWPAALAIVSGGIAATLLAGLAFAARPLAARPARILRSRD
>NZ_CP027665.1|WP_106471935.1|1556616_1557330_+|ATP-binding-cassette-domain-containing-protein
MRMSPSPSEPALSLRQAALTLNGNAGPVNILHDLTFEVKHGESLALVGPSGSGKSSALMLMGGLERATGGSVIASGHDLAAMDEDALARFRRDRMGVVFQSFHLIPTMTALENVATPLELAGHRDAFARAAAELETVGLSGRADHYPAQMSGGEQQRVALARASAPRPEILLADEPTGNLDEANGAAIMDLLFGLRDRHGATLVLVTHAPELAARCDRVVRLRDGRVEDDATTEAAG
>NZ_CP027665.1|WP_106471934.1|1555970_1556624_-|arylesterase
MRKVLLALVIGLLAGHFSTAARAETVTVAMFGDSLTQGYGLVQSEGLVPQLQAWLDARGADARLINAGVSGDTTAGGLARIGWTLTGEVDAVVVALGGNDMLRGIDPAVSRANLDGILDAADRAGVGVLLMGMKAPGNFGPDYKAAFDGMYPDLARAHGVALHPNLLGGIGRAVGGDATRLRQYFQGDNIHPNAAGVAVIVEDIGPAVFDLTRELRR
>NZ_CP027665.1|WP_106471933.1|1555403_1555961_+|L,D-transpeptidase
MFSRRNFLAATAAASALPLPALAKTAEPFDPMPQYVRIKKQFLPGQILIVPRAFYLYYVTEPRKAIRYGVGVGKAGLEFTGSAIIQVKKEWPTWRPTDEMIERDPVTYGRFKDNDYVQPGGPDNPLGARALYLFQNGVDTYFRIHGTTQPQTIGQSVSNGCIRMLNEHVVDLYERVPVGTVVTVL
>NZ_CP027665.1|WP_106471944.1|1567479_1569054_+|2-isopropylmalate-synthase
MTTTTDTDRVLIFDTTLRDGEQSPGATMTHDEKLEIAGLLDEMGVDIIEAGFPIASEGDFKAVSEIAANARNAVICGLSRANLGDIDRCWEAVRNAKQPRIHTFIGTSPQHRAIPNLTRDEMADLIHQTVTHARNLCDNVQWSPMDATRTEWDYLARVVEIAIKAGATTINIPDTVGYTAPVESADLIRRLIAEVPGAADVVFSTHCHNDLGMATANSLAAVAGGARQIECTINGLGERAGNTALEEVVMALKVRHDIMPWQTGIDTSRIMNISRRVSTVSGFPVQFNKAVVGKNAFAHESGIHQDGMLKSADTFEIMRPEDIGLAGTSLPLGKHSGRAALRDKLRQLGYDVGDNQLRDIFVRFKELADRKKEVFDDDIVALMRAGEDPANDRLQVVSMKVVCGTGGPAESTVEMEIDGEDLSATAHGDGPVDATFKAIRKLFPNNAHLELYQVHAVTEGTDAQATVSVRLGEDGMIATGQSANTDTVVASARAYVNALNRLLVRREKTGPGSDMREISYKDVN
>NZ_CP027665.1|WP_106471945.1|1569241_1570288_+|rod-shape-determining-protein
MSILGNLGGLFSSDMAIDLGTANTLVYVKGRGVILSEPSVVAYHVKDGVKKVLAVGEDAKLMLGRTPGSIEAIRPMRQGVIADFDVAEEMIKHFIRKVHKRTTFSKPKIIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAAAIGAGMPITDPTGNMVVDIGGGTTEVAVLSLGDIVYAQSVRVGGDRMDESIINFLRRKENLLVGESTAERIKTSIGTARMPDDGRGASMHIRGRDLLNGVPKEIEISQAQVAEALAEPVQQICEAVMTALEATPPDLAADIVDRGVMLTGGGALLGDLDLALRERTGLAVSIADESLTCVALGTGKALEYEKQLRHAIDYDS
>NZ_CP027665.1|WP_106471946.1|1570347_1571259_+|rod-shape-determining-protein-MreC
MAKDRSQNDDFAGPLRRLLVALLCLFLLAVFIVWRIDSPRVERFRAQVTDRVVPSLDWAMRPVTGAVNLVRDFQSYQRLVEQNANLRSELRRMRAWREAALQLEQENARLLDLNNVRLDPQLTYVTGVVMADSGSPFRQSVLLNVGARDGIVDGWAAMDGIGLVGRISGVGKTTSRVILLTDPVSAVPAQIRPSGQTAMIIGDNSATPIVDFLENLDLVRPGDRVISSGDGGVFPAGLLIGSVAADPSGRLRVRLAADFERLEYLRVLRHHGHEGITDPGGIVAPRTAVQADRTEPGEGGGDG
>NZ_CP027665.1|WP_106474007.1|1571251_1571794_+|rod-shape-determining-protein-MreD
MDSAAPLTRLWLMRAAYFGLVLVILFFHLLPLDTVPRRIAPPDLFEALTFAWVLRRPDYVPPLSIAAAMLLADLLLQRPPGLTALAVLLGAEFLRARGPGMRDTGFLFEWLVVALVMLAIPVLTRVVMGLSLTVQSPLSLVLSRAGFTILAYPLVVAASQALLGVRRPAPGSGEQVGLRA
>NZ_CP027665.1|WP_106471947.1|1571790_1573734_+|penicillin-binding-protein-2
MKRNPQELEQVHRRMSRRTLLVGGLMGGFAGALAWRMHRLQVDEADQFRLLAEENRINIRLIAPARGKLFDREGRVIARNTPSYRIIIVPEDAGDVDAVISRLSQLVELDQEDLNRAMTEMKRSPPFLPVTLADQVSWEAVSRVAVNAPALPGVTPEVGLTREYPRNADFAHVVGYVGPVSDYDLSKIEDPEPVLRIPRFQIGKVGLEAKREDVLRGKAGAKRVEVNATGRVMRELDRREGQPGADLQLTVDAQLQTYVQARLAGESAAAVVIDCADGDLRAIASAPSFDPNLFVRGISVGDYRALTEDKYRPLANKTVQGTYPPGSTFKMITAMAALEEGLVGPEETVWCPGHMEVSGRRFHCWRRGGHGHVNLLNSLKQSCDVYYYDLALRVGIDKISAMAHRFGLGERHDIPMSAVARGLAPDRAWKNQVHDQDWRVGDTVNASIGQGYMLASPLQLAIMSARIATGRAVAPRLVKSVDGIEQPSGGGGDLGVNRANLDRIRRAMYAVSNDRRGTAYRNRIIAEEQRMAGKTGTSQVRNITKEERARGVIRNSDLPWERRDHALFVCYAPYENPRFAVSVVVEHGGGGSTAAAPIARDVLLQALYGGPPPLTAYPKGDRGRIKAQQEQMEQDFPALRAEASDRA
>NZ_CP027665.1|WP_106471948.1|1573730_1574870_+|rod-shape-determining-protein-RodA
MSYLESTVQSTPTGLRKVLYLNWPLTLLLTAVACVGFLMLYSVAGGSFQPWAEPQMKRFVLGLAVMLAIAMVPIWFWRNMAALAYGGSVLLLIAVEMFGTVGMGAQRWIDIGFMRLQPSELMKITLVMLLAAYYDWLPAERTSRPFWVLVPVAIILFPTFLVLRQPDLGTSILLLAAGGGLMFLAGVHWAYFVAVITAGVGLITAVFKSRGTDWQLLKDYQFRRIDTFLDPSQDPLGAGYHITQSKIALGSGGWGGRGFMQGTQTRLNFLPEKHTDFIFTTLAEEFGFIGGISILTLYALIIVFCVATALATRDRFSSLVTLGIAMTFFLFFAVNMSMVMGLAPVVGVPLPMVSYGGSAMLVLMAAFGIVQSAHIHRPR
>NZ_CP027665.1|WP_106471949.1|1574877_1575810_+|glyoxylate/hydroxypyruvate-reductase-A
MTVNVLFAARAENWDTYRAPLSDALDRAGVAADLRTDFPPELVDYIVYAPSSPLRDFTPFTRLRAVLSLWAGVETITGNRTLGVPLARMVDDGLTRGMVEWVTGHVMRHHLGMDAQITGQDGVWRKAIPPLAADRPVTILGLGELGRACGETLAALGFPVTGWSRSPKSIPGLLCLHGPDGLTAALDSAQILVLLLPDTPATTNVLNAETLARLPRGATVINPGRGTLIDDDALLAALDAGQVGHATLDVFRTEPLPADHPYWAHPRVTVTPHIASETRAETASQAIAENIRRGEAAEPFLHLVDRDLGY
>NZ_CP027665.1|WP_106471950.1|1575803_1576172_-|hypothetical-protein
MTGDDFNAFCGSLPAATHSVQWGGSDVWKVGGKVFAICGWGTGEAAFTFKVSDIAYEVLTGMEGLRPAPYLASRGFKWVQHHAAPGLSDDELKRHIRASYEMIRDALSRARRAELGLTGPDQ
>NZ_CP027665.1|WP_106471951.1|1576168_1578184_-|M3-family-metallopeptidase
MTNPLLDTWDTPFGIAPFAAISDADFDPALDRALAAHRAEIDAIAGDPAPADFDNTIGALEAAGRDLDRVLSVFSTVAGADSTPDREALQRAFSPKLAAHFSDISANKALFGRVDDLWQRRDTLGLDDEQARVLMLTRRGFVRSGAALRGADETRMKDIKARLATLGTAFTQNLLADERDWSMPLGPGDLDGLPDFVIAAARAAGEEKGAPGPVVTLSRSLIVPFLQFSARRDLRERAWRAWSARGANGGDTDNRDIAAEILALREERAGLLGYDNFADYKLETEMAGSPEKVRDLLMAVWEPARARVEADAGVLTAMMQADGVNGPLEPWDWHFYAEKRRRAEHDLDEAALKPYLQLDRIIEAAFACAQRLFGLKFAPLPDLDLYHPDCRAWEVTRDGQHVAVFIGDYFARGSKRSGAWCSAMRSQAKFPEPQTPVVINVCNFAKGEPALLSWDDARTLFHEFGHALHQMLSDVTYESISGTSVARDFVELPSQLYEHWLEVPEVLANYATHAETGAPMPRDLLDRLLAASTYDMGFQTVEYVASALVDLAFHDGPAPADPMARQAEVLAGIGMPHAIAMRHATPHFAHVFAGDGYSCGYYSYMWSEVMDADAFAAFEEAGGPFDADRARALEDHILSRGGSAEAADLYLAFRGRLPGVEALLRGRGLAA
>NZ_CP027665.1|WP_106471952.1|1578186_1579230_-|HesA/MoeB/ThiF-family-protein
MLLVLILCGALWGLGWLVGSPPRLRWVMIALLLAGVILGHLLLPDGHALRVVTGGAAAPWFLLLGCAALAGAYALVVRWLRRRAVAREEPVPHAAGFSDAELDRYARHIVLREIGGPGQKKLKAARVLVIGAGGLGAPALQYLAAAGVGTIGVIDDDVVENANLQRQVIHRDADIGLPKVFSAQRAMEAQNPAVAVRPYHRRLTGEVAADLFADFDLVLDGSDSSETRYLVNRTAVAAGIPLVSGALSQWEGQLSIFDPAHGGPCYQCVFPEAPAPGLAPSCAEAGVLGPLPGVIGAMMAVEAIKLITGAGAVPRGDMVIYDALWGETRKIALKRRADCPVCDKRTG

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Crispr_ID: NZ_CP027665_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027665_2

1643594-1643749

Orphan

Consensus_repeat	Method
TCGAGATCGGCGAGAAGATCGTC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP027665_2

>merge|NZ_CP027665|2|1643594-1643749|CRISPRCasFinder
CCCAGCTCGGCCACGAGGTCGTCCAGATCCTCTCCCGGCCCAGATTCGGGTTCGGCATCATCGGATGCCCCCAGTTCGGCGAGCAGGTCGTCCAGATCGTCCCCACCGGTTTCCGGCTCGGGGTCGGCATCCCCCAGATCGCCAAGGAGATCGTCG

>NZ_CP027665|2|2|1643594-1643749|CRISPRCasFinder
CCCAGCTCGGCCACGAGGTCGTC	CAGATCCTCTCCCGGCCCAGATTCGGGTTCGGCATCATCGGATGCC
CCCAGTTCGGCGAGCAGGTCGTC	CAGATCGTCCCCACCGGTTTCCGGCTCGGGGTCGGCATCC
CCCAGATCGCCAAGGAGATCGTCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027665.1\|WP_106474015.1\|1652567_1653389_-\|virulence-protein-SciE-type	unknown	unknown	gnl\|CDD\|226862
NZ_CP027665.1\|WP_106471996.1\|1634249_1635665_-\|type-VI-secretion-system-protein-TssL	unknown	unknown	gnl\|CDD\|180801
NZ_CP027665.1\|WP_106471992.1\|1627094_1629284_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP027665.1\|WP_106471997.1\|1635681_1637022_-\|type-VI-secretion-system-baseplate-subunit-TssK	unknown	unknown	gnl\|CDD\|377569
NZ_CP027665.1\|WP_106471999.1\|1638575_1638881_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|269823
NZ_CP027665.1\|WP_106472008.1\|1653477_1653981_-\|type-VI-secretion-system-tube-protein-Hcp	unknown	unknown	gnl\|CDD\|377536
NZ_CP027665.1\|WP_106471994.1\|1630006_1630687_-\|type-VI-secretion-system-associated-protein-TagF	unknown	unknown	gnl\|CDD\|370730
NZ_CP027665.1\|WP_106471998.1\|1637043_1638567_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	unknown	unknown	gnl\|CDD\|225987
NZ_CP027665.1\|WP_106472007.1\|1652080_1652575_-\|type-VI-secretion-system-baseplate-subunit-TssE	unknown	unknown	gnl\|CDD\|226049
NZ_CP027665.1\|WP_106472000.1\|1638877_1639489_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027665.1\|WP_106472006.1\|1650198_1652076_-\|type-VI-secretion-system-baseplate-subunit-TssF	unknown	unknown	gnl\|CDD\|377574
NZ_CP027665.1\|WP_106472009.1\|1654047_1655547_-\|type-VI-secretion-system-contractile-sheath-large-subunit	unknown	unknown	gnl\|CDD\|226048
NZ_CP027665.1\|WP_106471993.1\|1629287_1630010_-\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NZ_CP027665.1\|WP_106472003.1\|1645523_1646378_-\|ion-transporter	unknown	unknown	gnl\|CDD\|366146
NZ_CP027665.1\|WP_106471995.1\|1630686_1634253_-\|type-VI-secretion-system-membrane-subunit-TssM	unknown	unknown	gnl\|CDD\|274531
NZ_CP027665.1\|WP_106472001.1\|1639497_1641663_-\|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl\|CDD\|274542
NZ_CP027665.1\|WP_106472004.1\|1646436_1649142_-\|type-VI-secretion-system-ATPase-TssH	unknown	unknown	gnl\|CDD\|274528
NZ_CP027665.1\|WP_106472005.1\|1649176_1650235_-\|type-VI-secretion-system-baseplate-subunit-TssG	unknown	unknown	gnl\|CDD\|377755
NZ_CP027665.1\|WP_106472011.1\|1656134_1657202_-\|type-VI-secretion-system-protein-TssA	unknown	unknown	gnl\|CDD\|274544
NZ_CP027665.1\|WP_106472010.1\|1655550_1656072_-\|type-VI-secretion-system-contractile-sheath-small-subunit	unknown	unknown	gnl\|CDD\|377529

Protein	Function_ID	Function_description	E-value
NZ_CP027665.1\|WP_106474015.1\|1652567_1653389_-\|virulence-protein-SciE-type	gnl\|CDD\|226862	COG4455, ImpE, Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only].	7.40096e-82
NZ_CP027665.1\|WP_106471996.1\|1634249_1635665_-\|type-VI-secretion-system-protein-TssL	gnl\|CDD\|180801	PRK07033, PRK07033, DotU family type VI secretion system protein.	1.33611e-128
NZ_CP027665.1\|WP_106471992.1\|1627094_1629284_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.45269e-71
NZ_CP027665.1\|WP_106471997.1\|1635681_1637022_-\|type-VI-secretion-system-baseplate-subunit-TssK	gnl\|CDD\|377569	pfam05936, T6SS_VasE, Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE. T6SS_VasE is a family of of bacterial proteins that are essential for the type VI pathogenic secretion system, although the exact function of this particular component of the system is still not known.	0
NZ_CP027665.1\|WP_106471999.1\|1638575_1638881_-\|hypothetical-protein	gnl\|CDD\|269823	cd14738, PAAR_2, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	8.42533e-14
NZ_CP027665.1\|WP_106472008.1\|1653477_1653981_-\|type-VI-secretion-system-tube-protein-Hcp	gnl\|CDD\|377536	pfam05638, T6SS_HCP, Type VI secretion system effector, Hcp. HCP is a family of proteins which are expressed in up to 1000 copies in Gram-negative bacteria. Together these copies aggregate into a needle-like shaft or tube that will penetrate other bacteria via a puncturing protein attached to its head. Initially Hcp forms a hexameric structure with a central channel of 40 Angstroms. These hexamers pile up one on top of each other forming nanotubes resembling the gp19 tail phage tube.	2.00304e-23
NZ_CP027665.1\|WP_106471993.1\|1629287_1630010_-\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.9695e-60
NZ_CP027665.1\|WP_106471998.1\|1637043_1638567_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	gnl\|CDD\|225987	COG3456, COG3456, Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular transport; Signal transduction mechanisms].	4.41287e-54
NZ_CP027665.1\|WP_106472007.1\|1652080_1652575_-\|type-VI-secretion-system-baseplate-subunit-TssE	gnl\|CDD\|226049	COG3518, COG3518, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	4.16159e-30
NZ_CP027665.1\|WP_106471994.1\|1630006_1630687_-\|type-VI-secretion-system-associated-protein-TagF	gnl\|CDD\|370730	pfam09867, DUF2094, Uncharacterized protein conserved in bacteria (DUF2094). This domain, found in various hypothetical prokaryotic proteins, has no known function.	4.50518e-41
NZ_CP027665.1\|WP_106472006.1\|1650198_1652076_-\|type-VI-secretion-system-baseplate-subunit-TssF	gnl\|CDD\|377574	pfam05947, T6SS_TssF, Type VI secretion system, TssF. This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssF. TssF is homologs to phage tail proteins and is required for proper assembly of the Hcp tube (the T6SS inner tube) in bacteria.	0
NZ_CP027665.1\|WP_106472009.1\|1654047_1655547_-\|type-VI-secretion-system-contractile-sheath-large-subunit	gnl\|CDD\|226048	COG3517, COG3517, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	0
NZ_CP027665.1\|WP_106472003.1\|1645523_1646378_-\|ion-transporter	gnl\|CDD\|366146	pfam00520, Ion_trans, Ion transport protein. This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.	8.74293e-32
NZ_CP027665.1\|WP_106471995.1\|1630686_1634253_-\|type-VI-secretion-system-membrane-subunit-TssM	gnl\|CDD\|274531	TIGR03348, VI_IcmF, type VI secretion protein IcmF. Members of this protein family are IcmF homologs and tend to be associated with type VI secretion systems. [Cellular processes, Pathogenesis].	0
NZ_CP027665.1\|WP_106472001.1\|1639497_1641663_-\|type-VI-secretion-system-tip-protein-VgrG	gnl\|CDD\|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	0
NZ_CP027665.1\|WP_106472004.1\|1646436_1649142_-\|type-VI-secretion-system-ATPase-TssH	gnl\|CDD\|274528	TIGR03345, VI_ClpV1, type VI secretion ATPase, ClpV1 family. Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP027665.1\|WP_106472005.1\|1649176_1650235_-\|type-VI-secretion-system-baseplate-subunit-TssG	gnl\|CDD\|377755	pfam06996, T6SS_TssG, Type VI secretion, TssG. This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssG. TssG is homologs to phage tail proteins and is required for proper assembly of the Hcp tube in bacteria.One other member in this family, SciB (Q93IT4) from Salmonella enterica, is thought to be involved in virulence.	1.37033e-113
NZ_CP027665.1\|WP_106472011.1\|1656134_1657202_-\|type-VI-secretion-system-protein-TssA	gnl\|CDD\|274544	TIGR03363, VI_chp_8, type VI secretion-associated protein, ImpA family. This protein family is one of two related families in type VI secretion systems that contain an ImpA-related N-terminal domain (pfam06812).	2.31216e-62
NZ_CP027665.1\|WP_106472010.1\|1655550_1656072_-\|type-VI-secretion-system-contractile-sheath-small-subunit	gnl\|CDD\|377529	pfam05591, T6SS_VipA, Type VI secretion system, VipA, VC_A0107 or Hcp2. VipA is a family of Gram-negative bacterial proteins that form part of the type VI pathogenic secretion system. Members have been variously defined as VC_A0107 family, Hcp2 and VipA, for ClpV-interacting proteins. VipB and VipA proteins interact very closely to form the shaft of the pathogenic penetrating needle system.	1.67976e-81

>NZ_CP027665.1|WP_106472001.1|1639497_1641663_-|type-VI-secretion-system-tip-protein-VgrG
MPVSKATDYSVVWMSGDYVSEDLMLHSAIVDEGISKLTRARVLFMSKSPDIDLDEFLGRAMRLHVQTEGEAERVITGICTSVEHLGFQGTYDFYTAEFRPKLWLLTRTSDCRVFQNKTAVEIIKQVMDEAGLTDYTDSLTGTYETRTYCLQYRESDFSFISRLMEEEGIYYLFRNALDSTSPENMILCDALSAHEDCPERSEFKYLPLKNKERVYEDAIAEWAVSGEMRRGKVTLADFDFEAPSADTTVVQQIQSGGNPHNSSEVYEYPGRYRNVSALGNARAQVRMEADAARYAQMRGTGMIRTLCAGGKMSFALRDGTEYSPKVEGYVGDYIVTQATHYFMEEFSFQGGGKRGRERGGDARTASRSGRDTKDGDEPKVLMPRNWDFPDEIKDMPFPVFTRFGAIPEAVQYRAPLTTPWPRVTGLQTATVVGQNGEEIWTDEHGRIKIQFHWDREGKDDENSSCWVRVVTPWSGKEWGFVAVPRMGQEVVIQFEEGDPDRPICTGMLYNADTMPPYTYPQDATQLGIKTQSSKDAEGYNELMFDDKAGEELMRVQAQKDHQVLIKNKSVVTVGLDEVNAGDHDEDGSVSRVVRNHVTETIQEGDHYFTISTGNQEIDIATDRTQTIGGNHTKTVTGNDDTTVEQGDLTIGVSSGSIAIEAAMEITLTVGGSSITIDNSGVTISAPMVTISADGMAEMSGTTTTVKGDTLLTLKGGVTKIN
>NZ_CP027665.1|WP_106472000.1|1638877_1639489_-|hypothetical-protein
MSERFKNMVKVPDQPAAKLLARANIRLKTRLDAPASASAEAVLEELDGKKAMIDMLLLMSVLLPPRERVWWACLAARDYIGPKSDKDPPSLAASEIWVFKPTEENRNAARNTLDHAYVDDDTVNCATAVLYADGTLGPGDLKEFPAPAGAAEAAVFTMNMVALKHLSARFEAHGQLLIDRAVDIARGGSGRVEAKVAQEEAGT
>NZ_CP027665.1|WP_106471999.1|1638575_1638881_-|hypothetical-protein
MTRPQARVSDQVLCAMFSVTPAGVTVPGTSAIIPPCAPTVLVGNLPAARIGDLHPSGTGPHPNVSSSATVIIQNMPACRVGDSTACGGAITKGDFTVLTGG
>NZ_CP027665.1|WP_106471998.1|1637043_1638567_-|type-VI-secretion-system-associated-FHA-domain-protein-TagH
MPVTLKFQSSGTMPGNARPIQMQGGSLTVGRGPANDLVLPDPDRTLSKSHCVIEDHNGNIVIVDLSSNGTFLNYSKIPLGRTPTPLNNGDVLALGSYELLVEISDDLPDIDDLIAAPAAQGSVSPGRAENAPDPMALLDDAGPEGDFLDDLLGGSNKPTGPSQLNPVDPIDELLPPIGDEEDPFFGKPDDGRGDGPAQPMHNPSGQDAFSPQGTGQGAGQSLIPEDWDDDFLNPDPPAAAPPPQPSVVPAPQSETPPGNPPENQPEPPADPDAEPTTVPAAAERPDPPSRGATPPSAAEREAAQPAAPQPAATGDDALLRAFLEALGAEGVQLADEDPARTMARMGRVMKTLVTGMREILMTRTSIKSEFRIEQTMISAGGNNPLKFSVSPEQAIEAMVKPAARGYLGPESAAEQALDDIKAHEVAMLTGMEAALRGVLLKLDPEVLAGRIETSGALGSLLKGKKARYWEVYEKMYADISDQAENDFHDLFSREFARAYSEQLQKLK
>NZ_CP027665.1|WP_106471997.1|1635681_1637022_-|type-VI-secretion-system-baseplate-subunit-TssK
MSWDSKVLWTEGLFLQPHHFQQSERYTEALVTGLARRIRPYAWGLSALELDDEVLKVGQIALKSCAGLTQDGTVFRVPSSDDHPPALEVPETIKDCIVYLTVPQRRQGAVEVDLSGAEMSASRLRPSELEVTDTMGRDRKPTTLAVGKTRLQFALAVDDLADRLAIPVARIIEVRPDKEIVLDQAFIPSCLDIRAAAPLDGFLRELEGLLSHRMQALAGRLSESGGARGVAEVSDFLLLTIINRMLPVVRHLTTIENLHPEDLFRTCAALAGELSVFMTADKYPPELPPYRHDDLTRSFTPLIRVLRQYLSSVLEQTAIPIALEARKYGISVGVIADRKLLGNAGFVLAVDADMPSEDVRRHFAGQAKIGPVEEIRQLVNSALPGITLRPLPVAPRQIPYHAGVVYFEMDADSPYWSKMTTSGGIAVHVSGQYPGLKMELWAIRNS
>NZ_CP027665.1|WP_106471996.1|1634249_1635665_-|type-VI-secretion-system-protein-TssL
MIDDDPFAEPDDTDKTVIKPNPGGRLSATPAQPAAAPQPSAPAEPAAPAEDAFGVPQSAAAPQDRRSGAKAPAIAMTGMNRLIACASPLFSLISRIRNRAQHMDPEKLRQSVVAEVRAFENRALQAGIPAQTVKVARYALCATLDDVVLNTPWGGQSSWGLQSMVGTFHRETVGGDRFYDLLARLEKEPGNNIDLLEFLYMCMSLGFEGRLRVEQGGSEKHQQIRAALARIIRAQRGPLEHDLSPHWEGVTKPFKALSAWRVVWIALGVTAGLLVAEFLGLSWALSRTTERVVGQLSVIDSGPVAELQRRAPPPPPTPATPTAEQQLLKVEGFLQEEIDEGIVEVFRKGNTLIIRVAGTGMFGSGSDTLQKDFVARIDRVAKSLNDEPGPVIVVGHSDNVPIRSSRFPSNMALSLARARSVMEGMARVMDDPSRLSAEGRADKEPIADNATRDGRAKNRRIEVLLVQEGDG
>NZ_CP027665.1|WP_106471995.1|1630686_1634253_-|type-VI-secretion-system-membrane-subunit-TssM
MKAVLKVLGSIYFALFFAALVLSLCVWFFAPFIGWGEFRPFDGILSRLITIGVLWLIFGLIMLIIFLRRRKRDKEMAEEIAEVAEAAAPEDDIAAEELGELKSKFRDAITALRKSKNGRRHLNELPWYVMIGPPGAGKTTAIVNSGLQFPLAAEMGKSAIGGVGGTRNCDWWFTNEAVLIDTAGRYTTQESDAETDNAAWLGFLSLLKKYRKRQPINGAMVAISLSDLCLQDEITQKAHAEAVRRRLNELRERLGVRFPVYVLFTKADLIAGFAEFFDHLGKEEREQVWGFTLPVDSGKGEASPVAGFDDEFAQLLGQLNAQSLERMQAETDHQKRALIAGFPAQVASMRGVARDFLNEVFQENRYQHRHALRGVYFTSGTQEGTPIDRLMLGMAQTFGIGRQAVGSGQGSGRSYFLTRLLETVIFNEAGLVSADDKVERRYRWTRRAAIAATVLIALATGAIWVRSYLGNTELLAAAEDHVSQYQAAAATLPPSPVGDTDLPPVVQALNILRDMPGNPVLDDPAPEGRLRYGLYQGEVVGTQAAQTYRAALNQRFLPRLLLRLEEQIGANVNNPDLLYEALKIYLMLGLQGPMNADLVKEWMQLDWSLAYPGVARQDLRADLASHLDALLSQPMQEVALNGPMVEQVQGILSEMPLAQRVYNGIINSATATALPKWRITEAGGPAVSRALVRSSGKPLNEGIEGIFTYDGFNNVFLPEAVSVAGRVQRESWVLGPRGEAEQTEGALLQLSRDVLDLYYNDYIARYDGILGDIDIMPMESLSHAAEITNVLSGPTSPIRNLLTEISNETKLTEDRSLLETDSLESGAKTVLSIEARQQLSIQSQIILEALTSAAAANTGEPPRPPGYYVEERFRWLHELVARPEGQPSQLDDLLGVLTDVYKQLNSMSFSGVTSSEASGEAIAQFQQVASRIDGPMERWSKQIIAGSSGIAADGTRASINARWQSSVLPFCEKALTDRYPFNRRARADVAMADFSKLFAPGGLIDGFFNDNLLKFVDTRSRPWTWKRVNDVDLGISPSVLQQMQYAAEIKDTFFGGSPHAAVKFQITPEALDPKAKSVLLEIDGQQVPFQHRAQPNPVAVTWPGTVGMARVTFAPDKRNLESQVSRDGPWAWFRLLDAAEVRKTNASDRKRVIFNIGGRIAIFQLQSGSVLNPFALPALAKFSCPKSM
>NZ_CP027665.1|WP_106471994.1|1630006_1630687_-|type-VI-secretion-system-associated-protein-TagF
MEAGFGAFGKMPAVGDFFRLSPPKGFVAVWDDWVQQTLLAAQSAFGPDWDAHYMSAPIWRFSLSPGLAGPRKAQGVLMPSVDRVGRRFPLTLVAGLPGPGPAALDHFADAGLFARLEDVALAALDDGMTRDRLAEDLAQVPVPGPRDCAPLRAAARGLVMTQPGPGGLLPDLAADLLAARTDRPSLWSAVIGGVPRLMICEGLPQGDEALGLFSLTAPIWSEARPI
>NZ_CP027665.1|WP_106471993.1|1629287_1630010_-|serine/threonine-protein-phosphatase
MTGPARFRYNAKTHVGLRRKVNEDSVLALPGHDIWLVSDGMGGHDAGDFASRLVADSVAMIPAGLDPTARMHALRDAIRAAHGAIQAEAAARGGNTIGATVVALMIANGHFVGLWAGDSRLYRLRAGEIEMLTTDHSVVAGLVLAGQMSWDEAENHPQSNAITRAVGIGDDFELDKIRGQIRPGDRFLLCSDGLTKYAGVATLARMLGSLPLETVTDELVQLALAGGGADNISVIVVDVI
>NZ_CP027665.1|WP_106471992.1|1627094_1629284_+|protein-kinase
MIDSRPGDAFQPGDLVNNTYRIESLLGRGGTSDVYKARSEISGRLVALKVLKAEFSGNDDYLVLLTREEGIREVRHDAVVRYSENHRTEHGLVYLVMDYVEGPALDRKLKQGPMPADEILTVCRRVAEGLQAAHDRNIVHRDLSPDNIILRDGDPAQAVIIDFGIAKDTNPGAETIVGNEFAGKYAYAAPEQLSGNTDARTDIYSLGALLLANFRGASPDIGNSPMEVVTRKAEPLNTEGVPEPLKTLIDRMTAPEPENRMQSAAEVLAFLDAPDAAPPAAPSDGGADPDATVIVPRARNADAPAATVAPAPDPRDKPAPASRGETRSRGGLFAMLAVVVLIAAGAGAWFSGALDGLLGPKYPIADPYTLIAEKRDGDGVNLTGHAPSEDALAALAGFAETGLGTSELQLASGDIPDSWGADVLALLRDMDGLNAWRVVVDGSSVDITGSTADKALQERLSAALASGLPGALTGRAEITLVPQFLAPDEVQAELDGLADCGPLTLPGVPQLGYGPQSAITVTGKVAGTATRVQLFDGLRDLAGDRNVVVDVEVLNPTLCLIESHLPTAPAGGIAIGFTVGDRDEPNPSGRFFVGENPVIDLTLPADVTDGYLSVSILDVSGNVFHLLPNINRQDNAVAGLRGGRDGDVTVRVAYPVADAGPGQIAFTVDDSTLGKSKILVLHSTAPLFDGMRPTSESAKGYAEALQAHAGVNGTRILSLDSRILETAKP
>NZ_CP027665.1|WP_106472003.1|1645523_1646378_-|ion-transporter
METSNQTGTLTLRARARDFIERPKVTNAILAVIIFNAVTLGLSTSQTMQDSIGGLLTVIDRVVLTIFVVELLIKFYAYGLRFFNSAWNIFDLVVVSVGLLPDKSGLSALRGLRVIRSLRLLSVIPQMRAVVQALLDALPGMGAVIIMISIIFYVFGVMATLMYGAAFDEWFGTLGRSLYSLFQIMTLESWSMGIVRPVMAEFPTAWAFFVPFIVITAFSVLNLFIGLLVNTMQSAVEAEAEAEFEQLRELVKSETDVVDEHVMELHGEIRALRAEVAALKDGRR
>NZ_CP027665.1|WP_106472004.1|1646436_1649142_-|type-VI-secretion-system-ATPase-TssH
MTEISRVALFGKLNRLGYQAVEGATVFCKMRGNPYVEVVHWLHQILNGQDSDLHRIIGHYDLDPGKIAAEMTRALDALPRGASTISDLSDHLMDAMERGWVWGSLLFSDSKVRTGYLLLGMLKTPALRNILNSMSPELGRIGPDDLADHFGEATDGSPEETLGAQDGTTVGGGAEPGEASGAMAPGAMGKGEALEQFCTDLTAQARAGEIDPIVGRDEEIRQIVDVLMRRRQNNPILTGEAGVGKTAVVEGFALRIARGDVPPALKDVRLLVLDVGLLQAGASMKGEFENRLRQVIDEVQASPTPIVMFVDETHTLVGAGGAAGTGDAANLLKPALARGTLRTIGATTWAEYKKYIEKDPALTRRFQVVHVEEPGIPKAVLMMRGIASMLEKHHQVQVLDEGIEAAVTLSARYIPARQLPDKSVSLLDTACARVAVSQHAVPAEVDDSRRRIEALTTELEIIDRDETAGYDVADRRVAVTAAKEAEETRLEGLTDRWDREKAVVEGILDLRAKLREGGTPVEAEPGSEEAEASPLSDEDRGRLLDELRAKNAELAEVQGDSPLILPIVDHQAVASVVGDWTGIPVGRMVKDEIETILNLDERLAQRVIGQDHAMKMIAKRVQTSRAGLDNPNKPIGVFLLAGTSGVGKTETALALAEVLYGGEQNVITINMSEYQEAHTVSSLKGAPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVHEIFFQVFDKGVMEDGEGRLIDFKNTLILLTSNVGTEMIMDLCADPDLMPDPEGIAKALRDPLLKVFPPALLGRLVTIPYYPLSPHMIAEITKLQLGRIKKRVTEAHGVPFDYTDAVVDEIVNRCQELESGGRMIDAIVTNTMLPDISAEFLRRMMEGHEVSKVVIDVTDGEFTYGFD
>NZ_CP027665.1|WP_106472005.1|1649176_1650235_-|type-VI-secretion-system-baseplate-subunit-TssG
MAAGTGPGSDDLRPGQLSLAERLEREPEKHHVFQALRILEAMHPETPRLGESRRPRQDPVRLGQEAETAFPPSTVAAFRPGEGGGPARLTNRFFGLFGPNGPLPLHLTAYARDRQRNHRDPTFLAFANMFTHRMMSLLYRAWASGQPAVSHDRGEDPVADKVAALAGFHGAGLRNRDAMPDLARLHFAGLLAPGPRHAEGLVSILSAFFDVPVRVQQFVGCWLDLEPDDRWQLGARTGLGQSTSIGQRVWSRAAKFRIRIGPLGLRDYERLLPGSGALERLRAIVRTYAGDELDWDVNLILAGDEVPRARLDGTTRLGHTGWIGGRLGGDDDRPDAEDLFLHPGLNGTAAQP
>NZ_CP027665.1|WP_106472006.1|1650198_1652076_-|type-VI-secretion-system-baseplate-subunit-TssF
MDTRLMKHYESELLFLRDMGAEFAAAYPKVASRLGMEGVEVLDPYVERLLEGVAFLSARVQLELELQYPSFTSNLLEIVYPHYLAPTPSMMIAAFEPDASNSAVKSGYVLPRQSVVRSRLMEGEQTPCEFRTAADLTLWAVEIEQAEYIDGRGELVAAGVAGAEGARAGVRLRLRRKDGGPIRDLPMDRLTLFLGGAAGNSWALLELLCTQGIGICGRSTDRRADWVERLEGWGIEHKGFGKDEALLPPTRRVFDGYRLLQEYFAMPERFLFVELQGLKPALKRATGPDVDLYVLLGEGRRDIASMVVPDAFTLNAVPAVNLFPKRCDRVHVTARDTEQHVLPSRTAGLDYEIYRIERVTGITGGGGDDVEFRPFYSTTDFTAAGEIHPAYYTLRRRMRQRSEKERLRGVRTSYLGSEVFLTLVDRRQAPYSAALDQLAVSALCTNRDLPLLLATGNEDVFQLPEGGPVRKIRLPVTPTRPHPTLAQGDTAWRLISHLSLNYLSIADGGNGDAAEALRELVGLYAPIGNRVTEKQLEGLVSVASRPIVRRMSDEVLSTALRGTEITIGFDDSFFEGSSVYVLGAVLERFFRRYATLNSFTETVLTTQTRGEIARWRPERGLGRMI
>NZ_CP027665.1|WP_106472007.1|1652080_1652575_-|type-VI-secretion-system-baseplate-subunit-TssE
MADKTIAERLQPSLLDRLTDDAPGNPKETRESRVIDLSRLRDIIQRDLSWLLNTSNIDNMIDAKAMPNVAKSVLNYGLTEVSGEFSTRERAEAIRRSIQRAVMLYEPRIMRGTVEVTLSADDSNDMTVALEIRADMWAQPMPLELYLRSKVDVTTGEVQVERSY
>NZ_CP027665.1|WP_106474015.1|1652567_1653389_-|virulence-protein-SciE-type
MVSPGPEDHLKSGDLDATLAALQDKVRADPSDARLRIFLFQLLCVLGDWKRAITQLKLAAEMDEAATMMAKTYREAIICEVYREKVFAGEKEPLIFGEPQEWLALLIEAQKVLAGGNPQGAADLRARAFDAAPATPGMINGEPFDWIADADMRLGPVLEAVINGRYFWLPFSAISALECEAPSDLRDAVWTAGMLTLANGGEVAALIPTRYAGTTATGDHAALLARATTWADAGADTFTGCGQRLLATDKSDVALMDIRSLTITGATAGQGDG
>NZ_CP027665.1|WP_106472008.1|1653477_1653981_-|type-VI-secretion-system-tube-protein-Hcp
MENTYVFIKGIDGESLEVGHPKWIPVKTITWDVKRTLDMTDLGTAQRGYANTAFNQIKMTSELSLHSTKLMLSVADGTPHKEIKIEMCRAGDSKGKGMEPYLIFKLSDSVIDEYEVSGGEEQIPEETWSIAYRHISIEYMKADPKSGALSKGGTFDWDVMTGQQGSA
>NZ_CP027665.1|WP_106472009.1|1654047_1655547_-|type-VI-secretion-system-contractile-sheath-large-subunit
MAEEQAQAEAGAEQTAFGSSEFEALLQKEFRPKSDQAKTAVESAVKTLAEQALARTDLISDDALRSIESIVAEIDKKLTEQVNLILHNPEFQQLESAWRGLHYLVNNTETDEMLKIRVMNISKKDMHKTLRKFKGTAWDQSPIFKKLYTEEFSQLGGEPYGSLVADYHFDHSPPDVELLGEMSKIAAAAHAPLITGAKPELFQMDSWSELSNPRDLTKIFQTPEYAAWRSLRESEDSKYVGLAMPRFLGRLPYGSKTDPVEEFAFEEDTEGADSNKYAWVNAAYGMATNITRSFKEFGWCSRIRGVESGGSLEGLPSHTFPTTDGGVDQKCPTEIAIDDRREAELAKNGMMPLIHRKNTDVATFIGAQSLHKPAEYDDPDATANANLAARLPYLFATCRFAHYLKCMVRDKVGSFKSRNDMEKWLQDWIDNYVDFNADVSSEREKSRKPLAAAEVVVEEVEGNPGYYSSKFYLRPHYQLEGLSVSLRLVSKLPSEKGGG
>NZ_CP027665.1|WP_106472010.1|1655550_1656072_-|type-VI-secretion-system-contractile-sheath-small-subunit
MADSSQKFIARNRAPRVQIEYDVELYGAEKKVQLPFVMGVMSDLAGKSEVEQPAVADRKFLEIDVDNFDERMKSMAPRAAFTVPNTLTGEGNLAVDITFESMDDFSPAAIARKVEPLRELLDARSQLSNLMTYMDGKTGAEELIGKIIQDPALLKTLAAQAAPKADDGAEEQE
>NZ_CP027665.1|WP_106472011.1|1656134_1657202_-|type-VI-secretion-system-protein-TssA
MNLEGFLQPMDEGSPSGENLEYDPVFMELELAAQPKEGTEMGNAVTEAEPPDYREMSKKAQEVLERSHDLRAAVYLADAALNMDGMAGFAEVTSYIRGCLEQYWDSCHPELDEDDDDDPTMRINTIQGLCGQPDGLGGPSPVFRSLRRAALTNSRGLGIFSMRDIDLATGQIPVPEGADAPDMTTITGAFRDTDGDWLAGTLAAARQANDDVRAISAVFDEQTPGQGPELDPLIKLLYRINQTLGEHAGGADPAPEGEAAPDAAALAPAAANAAAPAGGGGGAVGAINTPADVSNALDRIVDYYRRSEPSSPVPVLLERAKRLVNADFLTIVKDMAPEGLENVNLIGGIVEEEEY

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Crispr_ID: NZ_CP027665_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027665_3

1643831-1643914

Orphan

Consensus_repeat	Method
TCGAGATCGGCGAGAAGATCGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP027665_3

>merge|NZ_CP027665|3|1643831-1643914|CRISPRCasFinder
TCGAGATCGGCGAGAAGATCGTCCGGCGTATCGCCACCGGCGGGTTCCGGTTCGGTGGCCTCGAGATCGGCGAGAAGATCGTCG

>NZ_CP027665|3|3|1643831-1643914|CRISPRCasFinder
TCGAGATCGGCGAGAAGATCGTC	CGGCGTATCGCCACCGGCGGGTTCCGGTTCGGTGGCC
TCGAGATCGGCGAGAAGATCGTCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027665.1\|WP_106474015.1\|1652567_1653389_-\|virulence-protein-SciE-type	unknown	unknown	gnl\|CDD\|226862
NZ_CP027665.1\|WP_106471996.1\|1634249_1635665_-\|type-VI-secretion-system-protein-TssL	unknown	unknown	gnl\|CDD\|180801
NZ_CP027665.1\|WP_106471992.1\|1627094_1629284_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP027665.1\|WP_106471997.1\|1635681_1637022_-\|type-VI-secretion-system-baseplate-subunit-TssK	unknown	unknown	gnl\|CDD\|377569
NZ_CP027665.1\|WP_106471999.1\|1638575_1638881_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|269823
NZ_CP027665.1\|WP_106472008.1\|1653477_1653981_-\|type-VI-secretion-system-tube-protein-Hcp	unknown	unknown	gnl\|CDD\|377536
NZ_CP027665.1\|WP_106471994.1\|1630006_1630687_-\|type-VI-secretion-system-associated-protein-TagF	unknown	unknown	gnl\|CDD\|370730
NZ_CP027665.1\|WP_106471998.1\|1637043_1638567_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	unknown	unknown	gnl\|CDD\|225987
NZ_CP027665.1\|WP_106472007.1\|1652080_1652575_-\|type-VI-secretion-system-baseplate-subunit-TssE	unknown	unknown	gnl\|CDD\|226049
NZ_CP027665.1\|WP_106472000.1\|1638877_1639489_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027665.1\|WP_106472006.1\|1650198_1652076_-\|type-VI-secretion-system-baseplate-subunit-TssF	unknown	unknown	gnl\|CDD\|377574
NZ_CP027665.1\|WP_106472009.1\|1654047_1655547_-\|type-VI-secretion-system-contractile-sheath-large-subunit	unknown	unknown	gnl\|CDD\|226048
NZ_CP027665.1\|WP_106471993.1\|1629287_1630010_-\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NZ_CP027665.1\|WP_106472003.1\|1645523_1646378_-\|ion-transporter	unknown	unknown	gnl\|CDD\|366146
NZ_CP027665.1\|WP_106471995.1\|1630686_1634253_-\|type-VI-secretion-system-membrane-subunit-TssM	unknown	unknown	gnl\|CDD\|274531
NZ_CP027665.1\|WP_106472001.1\|1639497_1641663_-\|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl\|CDD\|274542
NZ_CP027665.1\|WP_106472004.1\|1646436_1649142_-\|type-VI-secretion-system-ATPase-TssH	unknown	unknown	gnl\|CDD\|274528
NZ_CP027665.1\|WP_106472005.1\|1649176_1650235_-\|type-VI-secretion-system-baseplate-subunit-TssG	unknown	unknown	gnl\|CDD\|377755
NZ_CP027665.1\|WP_106472011.1\|1656134_1657202_-\|type-VI-secretion-system-protein-TssA	unknown	unknown	gnl\|CDD\|274544
NZ_CP027665.1\|WP_106472010.1\|1655550_1656072_-\|type-VI-secretion-system-contractile-sheath-small-subunit	unknown	unknown	gnl\|CDD\|377529

Protein	Function_ID	Function_description	E-value
NZ_CP027665.1\|WP_106474015.1\|1652567_1653389_-\|virulence-protein-SciE-type	gnl\|CDD\|226862	COG4455, ImpE, Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only].	7.40096e-82
NZ_CP027665.1\|WP_106471996.1\|1634249_1635665_-\|type-VI-secretion-system-protein-TssL	gnl\|CDD\|180801	PRK07033, PRK07033, DotU family type VI secretion system protein.	1.33611e-128
NZ_CP027665.1\|WP_106471992.1\|1627094_1629284_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.45269e-71
NZ_CP027665.1\|WP_106471997.1\|1635681_1637022_-\|type-VI-secretion-system-baseplate-subunit-TssK	gnl\|CDD\|377569	pfam05936, T6SS_VasE, Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE. T6SS_VasE is a family of of bacterial proteins that are essential for the type VI pathogenic secretion system, although the exact function of this particular component of the system is still not known.	0
NZ_CP027665.1\|WP_106471999.1\|1638575_1638881_-\|hypothetical-protein	gnl\|CDD\|269823	cd14738, PAAR_2, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	8.42533e-14
NZ_CP027665.1\|WP_106472008.1\|1653477_1653981_-\|type-VI-secretion-system-tube-protein-Hcp	gnl\|CDD\|377536	pfam05638, T6SS_HCP, Type VI secretion system effector, Hcp. HCP is a family of proteins which are expressed in up to 1000 copies in Gram-negative bacteria. Together these copies aggregate into a needle-like shaft or tube that will penetrate other bacteria via a puncturing protein attached to its head. Initially Hcp forms a hexameric structure with a central channel of 40 Angstroms. These hexamers pile up one on top of each other forming nanotubes resembling the gp19 tail phage tube.	2.00304e-23
NZ_CP027665.1\|WP_106471993.1\|1629287_1630010_-\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.9695e-60
NZ_CP027665.1\|WP_106471998.1\|1637043_1638567_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	gnl\|CDD\|225987	COG3456, COG3456, Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular transport; Signal transduction mechanisms].	4.41287e-54
NZ_CP027665.1\|WP_106472007.1\|1652080_1652575_-\|type-VI-secretion-system-baseplate-subunit-TssE	gnl\|CDD\|226049	COG3518, COG3518, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	4.16159e-30
NZ_CP027665.1\|WP_106471994.1\|1630006_1630687_-\|type-VI-secretion-system-associated-protein-TagF	gnl\|CDD\|370730	pfam09867, DUF2094, Uncharacterized protein conserved in bacteria (DUF2094). This domain, found in various hypothetical prokaryotic proteins, has no known function.	4.50518e-41
NZ_CP027665.1\|WP_106472006.1\|1650198_1652076_-\|type-VI-secretion-system-baseplate-subunit-TssF	gnl\|CDD\|377574	pfam05947, T6SS_TssF, Type VI secretion system, TssF. This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssF. TssF is homologs to phage tail proteins and is required for proper assembly of the Hcp tube (the T6SS inner tube) in bacteria.	0
NZ_CP027665.1\|WP_106472009.1\|1654047_1655547_-\|type-VI-secretion-system-contractile-sheath-large-subunit	gnl\|CDD\|226048	COG3517, COG3517, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	0
NZ_CP027665.1\|WP_106472003.1\|1645523_1646378_-\|ion-transporter	gnl\|CDD\|366146	pfam00520, Ion_trans, Ion transport protein. This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.	8.74293e-32
NZ_CP027665.1\|WP_106471995.1\|1630686_1634253_-\|type-VI-secretion-system-membrane-subunit-TssM	gnl\|CDD\|274531	TIGR03348, VI_IcmF, type VI secretion protein IcmF. Members of this protein family are IcmF homologs and tend to be associated with type VI secretion systems. [Cellular processes, Pathogenesis].	0
NZ_CP027665.1\|WP_106472001.1\|1639497_1641663_-\|type-VI-secretion-system-tip-protein-VgrG	gnl\|CDD\|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	0
NZ_CP027665.1\|WP_106472004.1\|1646436_1649142_-\|type-VI-secretion-system-ATPase-TssH	gnl\|CDD\|274528	TIGR03345, VI_ClpV1, type VI secretion ATPase, ClpV1 family. Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP027665.1\|WP_106472005.1\|1649176_1650235_-\|type-VI-secretion-system-baseplate-subunit-TssG	gnl\|CDD\|377755	pfam06996, T6SS_TssG, Type VI secretion, TssG. This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssG. TssG is homologs to phage tail proteins and is required for proper assembly of the Hcp tube in bacteria.One other member in this family, SciB (Q93IT4) from Salmonella enterica, is thought to be involved in virulence.	1.37033e-113
NZ_CP027665.1\|WP_106472011.1\|1656134_1657202_-\|type-VI-secretion-system-protein-TssA	gnl\|CDD\|274544	TIGR03363, VI_chp_8, type VI secretion-associated protein, ImpA family. This protein family is one of two related families in type VI secretion systems that contain an ImpA-related N-terminal domain (pfam06812).	2.31216e-62
NZ_CP027665.1\|WP_106472010.1\|1655550_1656072_-\|type-VI-secretion-system-contractile-sheath-small-subunit	gnl\|CDD\|377529	pfam05591, T6SS_VipA, Type VI secretion system, VipA, VC_A0107 or Hcp2. VipA is a family of Gram-negative bacterial proteins that form part of the type VI pathogenic secretion system. Members have been variously defined as VC_A0107 family, Hcp2 and VipA, for ClpV-interacting proteins. VipB and VipA proteins interact very closely to form the shaft of the pathogenic penetrating needle system.	1.67976e-81

>NZ_CP027665.1|WP_106472001.1|1639497_1641663_-|type-VI-secretion-system-tip-protein-VgrG
MPVSKATDYSVVWMSGDYVSEDLMLHSAIVDEGISKLTRARVLFMSKSPDIDLDEFLGRAMRLHVQTEGEAERVITGICTSVEHLGFQGTYDFYTAEFRPKLWLLTRTSDCRVFQNKTAVEIIKQVMDEAGLTDYTDSLTGTYETRTYCLQYRESDFSFISRLMEEEGIYYLFRNALDSTSPENMILCDALSAHEDCPERSEFKYLPLKNKERVYEDAIAEWAVSGEMRRGKVTLADFDFEAPSADTTVVQQIQSGGNPHNSSEVYEYPGRYRNVSALGNARAQVRMEADAARYAQMRGTGMIRTLCAGGKMSFALRDGTEYSPKVEGYVGDYIVTQATHYFMEEFSFQGGGKRGRERGGDARTASRSGRDTKDGDEPKVLMPRNWDFPDEIKDMPFPVFTRFGAIPEAVQYRAPLTTPWPRVTGLQTATVVGQNGEEIWTDEHGRIKIQFHWDREGKDDENSSCWVRVVTPWSGKEWGFVAVPRMGQEVVIQFEEGDPDRPICTGMLYNADTMPPYTYPQDATQLGIKTQSSKDAEGYNELMFDDKAGEELMRVQAQKDHQVLIKNKSVVTVGLDEVNAGDHDEDGSVSRVVRNHVTETIQEGDHYFTISTGNQEIDIATDRTQTIGGNHTKTVTGNDDTTVEQGDLTIGVSSGSIAIEAAMEITLTVGGSSITIDNSGVTISAPMVTISADGMAEMSGTTTTVKGDTLLTLKGGVTKIN
>NZ_CP027665.1|WP_106472000.1|1638877_1639489_-|hypothetical-protein
MSERFKNMVKVPDQPAAKLLARANIRLKTRLDAPASASAEAVLEELDGKKAMIDMLLLMSVLLPPRERVWWACLAARDYIGPKSDKDPPSLAASEIWVFKPTEENRNAARNTLDHAYVDDDTVNCATAVLYADGTLGPGDLKEFPAPAGAAEAAVFTMNMVALKHLSARFEAHGQLLIDRAVDIARGGSGRVEAKVAQEEAGT
>NZ_CP027665.1|WP_106471999.1|1638575_1638881_-|hypothetical-protein
MTRPQARVSDQVLCAMFSVTPAGVTVPGTSAIIPPCAPTVLVGNLPAARIGDLHPSGTGPHPNVSSSATVIIQNMPACRVGDSTACGGAITKGDFTVLTGG
>NZ_CP027665.1|WP_106471998.1|1637043_1638567_-|type-VI-secretion-system-associated-FHA-domain-protein-TagH
MPVTLKFQSSGTMPGNARPIQMQGGSLTVGRGPANDLVLPDPDRTLSKSHCVIEDHNGNIVIVDLSSNGTFLNYSKIPLGRTPTPLNNGDVLALGSYELLVEISDDLPDIDDLIAAPAAQGSVSPGRAENAPDPMALLDDAGPEGDFLDDLLGGSNKPTGPSQLNPVDPIDELLPPIGDEEDPFFGKPDDGRGDGPAQPMHNPSGQDAFSPQGTGQGAGQSLIPEDWDDDFLNPDPPAAAPPPQPSVVPAPQSETPPGNPPENQPEPPADPDAEPTTVPAAAERPDPPSRGATPPSAAEREAAQPAAPQPAATGDDALLRAFLEALGAEGVQLADEDPARTMARMGRVMKTLVTGMREILMTRTSIKSEFRIEQTMISAGGNNPLKFSVSPEQAIEAMVKPAARGYLGPESAAEQALDDIKAHEVAMLTGMEAALRGVLLKLDPEVLAGRIETSGALGSLLKGKKARYWEVYEKMYADISDQAENDFHDLFSREFARAYSEQLQKLK
>NZ_CP027665.1|WP_106471997.1|1635681_1637022_-|type-VI-secretion-system-baseplate-subunit-TssK
MSWDSKVLWTEGLFLQPHHFQQSERYTEALVTGLARRIRPYAWGLSALELDDEVLKVGQIALKSCAGLTQDGTVFRVPSSDDHPPALEVPETIKDCIVYLTVPQRRQGAVEVDLSGAEMSASRLRPSELEVTDTMGRDRKPTTLAVGKTRLQFALAVDDLADRLAIPVARIIEVRPDKEIVLDQAFIPSCLDIRAAAPLDGFLRELEGLLSHRMQALAGRLSESGGARGVAEVSDFLLLTIINRMLPVVRHLTTIENLHPEDLFRTCAALAGELSVFMTADKYPPELPPYRHDDLTRSFTPLIRVLRQYLSSVLEQTAIPIALEARKYGISVGVIADRKLLGNAGFVLAVDADMPSEDVRRHFAGQAKIGPVEEIRQLVNSALPGITLRPLPVAPRQIPYHAGVVYFEMDADSPYWSKMTTSGGIAVHVSGQYPGLKMELWAIRNS
>NZ_CP027665.1|WP_106471996.1|1634249_1635665_-|type-VI-secretion-system-protein-TssL
MIDDDPFAEPDDTDKTVIKPNPGGRLSATPAQPAAAPQPSAPAEPAAPAEDAFGVPQSAAAPQDRRSGAKAPAIAMTGMNRLIACASPLFSLISRIRNRAQHMDPEKLRQSVVAEVRAFENRALQAGIPAQTVKVARYALCATLDDVVLNTPWGGQSSWGLQSMVGTFHRETVGGDRFYDLLARLEKEPGNNIDLLEFLYMCMSLGFEGRLRVEQGGSEKHQQIRAALARIIRAQRGPLEHDLSPHWEGVTKPFKALSAWRVVWIALGVTAGLLVAEFLGLSWALSRTTERVVGQLSVIDSGPVAELQRRAPPPPPTPATPTAEQQLLKVEGFLQEEIDEGIVEVFRKGNTLIIRVAGTGMFGSGSDTLQKDFVARIDRVAKSLNDEPGPVIVVGHSDNVPIRSSRFPSNMALSLARARSVMEGMARVMDDPSRLSAEGRADKEPIADNATRDGRAKNRRIEVLLVQEGDG
>NZ_CP027665.1|WP_106471995.1|1630686_1634253_-|type-VI-secretion-system-membrane-subunit-TssM
MKAVLKVLGSIYFALFFAALVLSLCVWFFAPFIGWGEFRPFDGILSRLITIGVLWLIFGLIMLIIFLRRRKRDKEMAEEIAEVAEAAAPEDDIAAEELGELKSKFRDAITALRKSKNGRRHLNELPWYVMIGPPGAGKTTAIVNSGLQFPLAAEMGKSAIGGVGGTRNCDWWFTNEAVLIDTAGRYTTQESDAETDNAAWLGFLSLLKKYRKRQPINGAMVAISLSDLCLQDEITQKAHAEAVRRRLNELRERLGVRFPVYVLFTKADLIAGFAEFFDHLGKEEREQVWGFTLPVDSGKGEASPVAGFDDEFAQLLGQLNAQSLERMQAETDHQKRALIAGFPAQVASMRGVARDFLNEVFQENRYQHRHALRGVYFTSGTQEGTPIDRLMLGMAQTFGIGRQAVGSGQGSGRSYFLTRLLETVIFNEAGLVSADDKVERRYRWTRRAAIAATVLIALATGAIWVRSYLGNTELLAAAEDHVSQYQAAAATLPPSPVGDTDLPPVVQALNILRDMPGNPVLDDPAPEGRLRYGLYQGEVVGTQAAQTYRAALNQRFLPRLLLRLEEQIGANVNNPDLLYEALKIYLMLGLQGPMNADLVKEWMQLDWSLAYPGVARQDLRADLASHLDALLSQPMQEVALNGPMVEQVQGILSEMPLAQRVYNGIINSATATALPKWRITEAGGPAVSRALVRSSGKPLNEGIEGIFTYDGFNNVFLPEAVSVAGRVQRESWVLGPRGEAEQTEGALLQLSRDVLDLYYNDYIARYDGILGDIDIMPMESLSHAAEITNVLSGPTSPIRNLLTEISNETKLTEDRSLLETDSLESGAKTVLSIEARQQLSIQSQIILEALTSAAAANTGEPPRPPGYYVEERFRWLHELVARPEGQPSQLDDLLGVLTDVYKQLNSMSFSGVTSSEASGEAIAQFQQVASRIDGPMERWSKQIIAGSSGIAADGTRASINARWQSSVLPFCEKALTDRYPFNRRARADVAMADFSKLFAPGGLIDGFFNDNLLKFVDTRSRPWTWKRVNDVDLGISPSVLQQMQYAAEIKDTFFGGSPHAAVKFQITPEALDPKAKSVLLEIDGQQVPFQHRAQPNPVAVTWPGTVGMARVTFAPDKRNLESQVSRDGPWAWFRLLDAAEVRKTNASDRKRVIFNIGGRIAIFQLQSGSVLNPFALPALAKFSCPKSM
>NZ_CP027665.1|WP_106471994.1|1630006_1630687_-|type-VI-secretion-system-associated-protein-TagF
MEAGFGAFGKMPAVGDFFRLSPPKGFVAVWDDWVQQTLLAAQSAFGPDWDAHYMSAPIWRFSLSPGLAGPRKAQGVLMPSVDRVGRRFPLTLVAGLPGPGPAALDHFADAGLFARLEDVALAALDDGMTRDRLAEDLAQVPVPGPRDCAPLRAAARGLVMTQPGPGGLLPDLAADLLAARTDRPSLWSAVIGGVPRLMICEGLPQGDEALGLFSLTAPIWSEARPI
>NZ_CP027665.1|WP_106471993.1|1629287_1630010_-|serine/threonine-protein-phosphatase
MTGPARFRYNAKTHVGLRRKVNEDSVLALPGHDIWLVSDGMGGHDAGDFASRLVADSVAMIPAGLDPTARMHALRDAIRAAHGAIQAEAAARGGNTIGATVVALMIANGHFVGLWAGDSRLYRLRAGEIEMLTTDHSVVAGLVLAGQMSWDEAENHPQSNAITRAVGIGDDFELDKIRGQIRPGDRFLLCSDGLTKYAGVATLARMLGSLPLETVTDELVQLALAGGGADNISVIVVDVI
>NZ_CP027665.1|WP_106471992.1|1627094_1629284_+|protein-kinase
MIDSRPGDAFQPGDLVNNTYRIESLLGRGGTSDVYKARSEISGRLVALKVLKAEFSGNDDYLVLLTREEGIREVRHDAVVRYSENHRTEHGLVYLVMDYVEGPALDRKLKQGPMPADEILTVCRRVAEGLQAAHDRNIVHRDLSPDNIILRDGDPAQAVIIDFGIAKDTNPGAETIVGNEFAGKYAYAAPEQLSGNTDARTDIYSLGALLLANFRGASPDIGNSPMEVVTRKAEPLNTEGVPEPLKTLIDRMTAPEPENRMQSAAEVLAFLDAPDAAPPAAPSDGGADPDATVIVPRARNADAPAATVAPAPDPRDKPAPASRGETRSRGGLFAMLAVVVLIAAGAGAWFSGALDGLLGPKYPIADPYTLIAEKRDGDGVNLTGHAPSEDALAALAGFAETGLGTSELQLASGDIPDSWGADVLALLRDMDGLNAWRVVVDGSSVDITGSTADKALQERLSAALASGLPGALTGRAEITLVPQFLAPDEVQAELDGLADCGPLTLPGVPQLGYGPQSAITVTGKVAGTATRVQLFDGLRDLAGDRNVVVDVEVLNPTLCLIESHLPTAPAGGIAIGFTVGDRDEPNPSGRFFVGENPVIDLTLPADVTDGYLSVSILDVSGNVFHLLPNINRQDNAVAGLRGGRDGDVTVRVAYPVADAGPGQIAFTVDDSTLGKSKILVLHSTAPLFDGMRPTSESAKGYAEALQAHAGVNGTRILSLDSRILETAKP
>NZ_CP027665.1|WP_106472003.1|1645523_1646378_-|ion-transporter
METSNQTGTLTLRARARDFIERPKVTNAILAVIIFNAVTLGLSTSQTMQDSIGGLLTVIDRVVLTIFVVELLIKFYAYGLRFFNSAWNIFDLVVVSVGLLPDKSGLSALRGLRVIRSLRLLSVIPQMRAVVQALLDALPGMGAVIIMISIIFYVFGVMATLMYGAAFDEWFGTLGRSLYSLFQIMTLESWSMGIVRPVMAEFPTAWAFFVPFIVITAFSVLNLFIGLLVNTMQSAVEAEAEAEFEQLRELVKSETDVVDEHVMELHGEIRALRAEVAALKDGRR
>NZ_CP027665.1|WP_106472004.1|1646436_1649142_-|type-VI-secretion-system-ATPase-TssH
MTEISRVALFGKLNRLGYQAVEGATVFCKMRGNPYVEVVHWLHQILNGQDSDLHRIIGHYDLDPGKIAAEMTRALDALPRGASTISDLSDHLMDAMERGWVWGSLLFSDSKVRTGYLLLGMLKTPALRNILNSMSPELGRIGPDDLADHFGEATDGSPEETLGAQDGTTVGGGAEPGEASGAMAPGAMGKGEALEQFCTDLTAQARAGEIDPIVGRDEEIRQIVDVLMRRRQNNPILTGEAGVGKTAVVEGFALRIARGDVPPALKDVRLLVLDVGLLQAGASMKGEFENRLRQVIDEVQASPTPIVMFVDETHTLVGAGGAAGTGDAANLLKPALARGTLRTIGATTWAEYKKYIEKDPALTRRFQVVHVEEPGIPKAVLMMRGIASMLEKHHQVQVLDEGIEAAVTLSARYIPARQLPDKSVSLLDTACARVAVSQHAVPAEVDDSRRRIEALTTELEIIDRDETAGYDVADRRVAVTAAKEAEETRLEGLTDRWDREKAVVEGILDLRAKLREGGTPVEAEPGSEEAEASPLSDEDRGRLLDELRAKNAELAEVQGDSPLILPIVDHQAVASVVGDWTGIPVGRMVKDEIETILNLDERLAQRVIGQDHAMKMIAKRVQTSRAGLDNPNKPIGVFLLAGTSGVGKTETALALAEVLYGGEQNVITINMSEYQEAHTVSSLKGAPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVHEIFFQVFDKGVMEDGEGRLIDFKNTLILLTSNVGTEMIMDLCADPDLMPDPEGIAKALRDPLLKVFPPALLGRLVTIPYYPLSPHMIAEITKLQLGRIKKRVTEAHGVPFDYTDAVVDEIVNRCQELESGGRMIDAIVTNTMLPDISAEFLRRMMEGHEVSKVVIDVTDGEFTYGFD
>NZ_CP027665.1|WP_106472005.1|1649176_1650235_-|type-VI-secretion-system-baseplate-subunit-TssG
MAAGTGPGSDDLRPGQLSLAERLEREPEKHHVFQALRILEAMHPETPRLGESRRPRQDPVRLGQEAETAFPPSTVAAFRPGEGGGPARLTNRFFGLFGPNGPLPLHLTAYARDRQRNHRDPTFLAFANMFTHRMMSLLYRAWASGQPAVSHDRGEDPVADKVAALAGFHGAGLRNRDAMPDLARLHFAGLLAPGPRHAEGLVSILSAFFDVPVRVQQFVGCWLDLEPDDRWQLGARTGLGQSTSIGQRVWSRAAKFRIRIGPLGLRDYERLLPGSGALERLRAIVRTYAGDELDWDVNLILAGDEVPRARLDGTTRLGHTGWIGGRLGGDDDRPDAEDLFLHPGLNGTAAQP
>NZ_CP027665.1|WP_106472006.1|1650198_1652076_-|type-VI-secretion-system-baseplate-subunit-TssF
MDTRLMKHYESELLFLRDMGAEFAAAYPKVASRLGMEGVEVLDPYVERLLEGVAFLSARVQLELELQYPSFTSNLLEIVYPHYLAPTPSMMIAAFEPDASNSAVKSGYVLPRQSVVRSRLMEGEQTPCEFRTAADLTLWAVEIEQAEYIDGRGELVAAGVAGAEGARAGVRLRLRRKDGGPIRDLPMDRLTLFLGGAAGNSWALLELLCTQGIGICGRSTDRRADWVERLEGWGIEHKGFGKDEALLPPTRRVFDGYRLLQEYFAMPERFLFVELQGLKPALKRATGPDVDLYVLLGEGRRDIASMVVPDAFTLNAVPAVNLFPKRCDRVHVTARDTEQHVLPSRTAGLDYEIYRIERVTGITGGGGDDVEFRPFYSTTDFTAAGEIHPAYYTLRRRMRQRSEKERLRGVRTSYLGSEVFLTLVDRRQAPYSAALDQLAVSALCTNRDLPLLLATGNEDVFQLPEGGPVRKIRLPVTPTRPHPTLAQGDTAWRLISHLSLNYLSIADGGNGDAAEALRELVGLYAPIGNRVTEKQLEGLVSVASRPIVRRMSDEVLSTALRGTEITIGFDDSFFEGSSVYVLGAVLERFFRRYATLNSFTETVLTTQTRGEIARWRPERGLGRMI
>NZ_CP027665.1|WP_106472007.1|1652080_1652575_-|type-VI-secretion-system-baseplate-subunit-TssE
MADKTIAERLQPSLLDRLTDDAPGNPKETRESRVIDLSRLRDIIQRDLSWLLNTSNIDNMIDAKAMPNVAKSVLNYGLTEVSGEFSTRERAEAIRRSIQRAVMLYEPRIMRGTVEVTLSADDSNDMTVALEIRADMWAQPMPLELYLRSKVDVTTGEVQVERSY
>NZ_CP027665.1|WP_106474015.1|1652567_1653389_-|virulence-protein-SciE-type
MVSPGPEDHLKSGDLDATLAALQDKVRADPSDARLRIFLFQLLCVLGDWKRAITQLKLAAEMDEAATMMAKTYREAIICEVYREKVFAGEKEPLIFGEPQEWLALLIEAQKVLAGGNPQGAADLRARAFDAAPATPGMINGEPFDWIADADMRLGPVLEAVINGRYFWLPFSAISALECEAPSDLRDAVWTAGMLTLANGGEVAALIPTRYAGTTATGDHAALLARATTWADAGADTFTGCGQRLLATDKSDVALMDIRSLTITGATAGQGDG
>NZ_CP027665.1|WP_106472008.1|1653477_1653981_-|type-VI-secretion-system-tube-protein-Hcp
MENTYVFIKGIDGESLEVGHPKWIPVKTITWDVKRTLDMTDLGTAQRGYANTAFNQIKMTSELSLHSTKLMLSVADGTPHKEIKIEMCRAGDSKGKGMEPYLIFKLSDSVIDEYEVSGGEEQIPEETWSIAYRHISIEYMKADPKSGALSKGGTFDWDVMTGQQGSA
>NZ_CP027665.1|WP_106472009.1|1654047_1655547_-|type-VI-secretion-system-contractile-sheath-large-subunit
MAEEQAQAEAGAEQTAFGSSEFEALLQKEFRPKSDQAKTAVESAVKTLAEQALARTDLISDDALRSIESIVAEIDKKLTEQVNLILHNPEFQQLESAWRGLHYLVNNTETDEMLKIRVMNISKKDMHKTLRKFKGTAWDQSPIFKKLYTEEFSQLGGEPYGSLVADYHFDHSPPDVELLGEMSKIAAAAHAPLITGAKPELFQMDSWSELSNPRDLTKIFQTPEYAAWRSLRESEDSKYVGLAMPRFLGRLPYGSKTDPVEEFAFEEDTEGADSNKYAWVNAAYGMATNITRSFKEFGWCSRIRGVESGGSLEGLPSHTFPTTDGGVDQKCPTEIAIDDRREAELAKNGMMPLIHRKNTDVATFIGAQSLHKPAEYDDPDATANANLAARLPYLFATCRFAHYLKCMVRDKVGSFKSRNDMEKWLQDWIDNYVDFNADVSSEREKSRKPLAAAEVVVEEVEGNPGYYSSKFYLRPHYQLEGLSVSLRLVSKLPSEKGGG
>NZ_CP027665.1|WP_106472010.1|1655550_1656072_-|type-VI-secretion-system-contractile-sheath-small-subunit
MADSSQKFIARNRAPRVQIEYDVELYGAEKKVQLPFVMGVMSDLAGKSEVEQPAVADRKFLEIDVDNFDERMKSMAPRAAFTVPNTLTGEGNLAVDITFESMDDFSPAAIARKVEPLRELLDARSQLSNLMTYMDGKTGAEELIGKIIQDPALLKTLAAQAAPKADDGAEEQE
>NZ_CP027665.1|WP_106472011.1|1656134_1657202_-|type-VI-secretion-system-protein-TssA
MNLEGFLQPMDEGSPSGENLEYDPVFMELELAAQPKEGTEMGNAVTEAEPPDYREMSKKAQEVLERSHDLRAAVYLADAALNMDGMAGFAEVTSYIRGCLEQYWDSCHPELDEDDDDDPTMRINTIQGLCGQPDGLGGPSPVFRSLRRAALTNSRGLGIFSMRDIDLATGQIPVPEGADAPDMTTITGAFRDTDGDWLAGTLAAARQANDDVRAISAVFDEQTPGQGPELDPLIKLLYRINQTLGEHAGGADPAPEGEAAPDAAALAPAAANAAAPAGGGGGAVGAINTPADVSNALDRIVDYYRRSEPSSPVPVLLERAKRLVNADFLTIVKDMAPEGLENVNLIGGIVEEEEY

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Crispr_ID: NZ_CP027665_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027665_4

1644011-1644228

Orphan

Consensus_repeat	Method
TCGAGATCGGCGAGAAGATCGTC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP027665_4

>merge|NZ_CP027665|4|1644011-1644228|CRISPRCasFinder
TCAAGACTGCCGAGGAGGTCGTCGAGATCATCATCCCCGTCGGTGACGGGTTCGGCACTGTCGAGCGTTGCAAGAACATCGTCGGTCGCAGCGTCCTGCACCGTGTCGGGCCCTGCCGTTTCAAGACTGCCGAGAATGTCATCCAGGTCCCCCTCTCCGGCGCCCTCCGGTTGGGTCTCATCCAGCGCGGCGCTTTCAAGCCCGGCCAGAACATCATC

>NZ_CP027665|4|4|1644011-1644228|CRISPRCasFinder
TCAAGACTGCCGAGGAGGTCGTC	GAGATCATCATCCCCGTCGGTGACGGGTTCGGCACTG
TCGAGCGTTGCAAGAACATCGTC	GGTCGCAGCGTCCTGCACCGTGTCGGGCCCTGCCGTT
TCAAGACTGCCGAGAATGTCATC	CAGGTCCCCCTCTCCGGCGCCCTCCGGTTGGGTCTCATCCAGCGCGGCGCTT
TCAAGCCCGGCCAGAACATCATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027665.1\|WP_106474015.1\|1652567_1653389_-\|virulence-protein-SciE-type	unknown	unknown	gnl\|CDD\|226862
NZ_CP027665.1\|WP_106471996.1\|1634249_1635665_-\|type-VI-secretion-system-protein-TssL	unknown	unknown	gnl\|CDD\|180801
NZ_CP027665.1\|WP_106471992.1\|1627094_1629284_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP027665.1\|WP_106471997.1\|1635681_1637022_-\|type-VI-secretion-system-baseplate-subunit-TssK	unknown	unknown	gnl\|CDD\|377569
NZ_CP027665.1\|WP_106471999.1\|1638575_1638881_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|269823
NZ_CP027665.1\|WP_106472008.1\|1653477_1653981_-\|type-VI-secretion-system-tube-protein-Hcp	unknown	unknown	gnl\|CDD\|377536
NZ_CP027665.1\|WP_106471994.1\|1630006_1630687_-\|type-VI-secretion-system-associated-protein-TagF	unknown	unknown	gnl\|CDD\|370730
NZ_CP027665.1\|WP_106471998.1\|1637043_1638567_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	unknown	unknown	gnl\|CDD\|225987
NZ_CP027665.1\|WP_106472007.1\|1652080_1652575_-\|type-VI-secretion-system-baseplate-subunit-TssE	unknown	unknown	gnl\|CDD\|226049
NZ_CP027665.1\|WP_106472000.1\|1638877_1639489_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027665.1\|WP_106472006.1\|1650198_1652076_-\|type-VI-secretion-system-baseplate-subunit-TssF	unknown	unknown	gnl\|CDD\|377574
NZ_CP027665.1\|WP_106472009.1\|1654047_1655547_-\|type-VI-secretion-system-contractile-sheath-large-subunit	unknown	unknown	gnl\|CDD\|226048
NZ_CP027665.1\|WP_106471993.1\|1629287_1630010_-\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NZ_CP027665.1\|WP_106472003.1\|1645523_1646378_-\|ion-transporter	unknown	unknown	gnl\|CDD\|366146
NZ_CP027665.1\|WP_106471995.1\|1630686_1634253_-\|type-VI-secretion-system-membrane-subunit-TssM	unknown	unknown	gnl\|CDD\|274531
NZ_CP027665.1\|WP_106472001.1\|1639497_1641663_-\|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl\|CDD\|274542
NZ_CP027665.1\|WP_106472004.1\|1646436_1649142_-\|type-VI-secretion-system-ATPase-TssH	unknown	unknown	gnl\|CDD\|274528
NZ_CP027665.1\|WP_106472005.1\|1649176_1650235_-\|type-VI-secretion-system-baseplate-subunit-TssG	unknown	unknown	gnl\|CDD\|377755
NZ_CP027665.1\|WP_106472011.1\|1656134_1657202_-\|type-VI-secretion-system-protein-TssA	unknown	unknown	gnl\|CDD\|274544
NZ_CP027665.1\|WP_106472010.1\|1655550_1656072_-\|type-VI-secretion-system-contractile-sheath-small-subunit	unknown	unknown	gnl\|CDD\|377529

Protein	Function_ID	Function_description	E-value
NZ_CP027665.1\|WP_106474015.1\|1652567_1653389_-\|virulence-protein-SciE-type	gnl\|CDD\|226862	COG4455, ImpE, Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only].	7.40096e-82
NZ_CP027665.1\|WP_106471996.1\|1634249_1635665_-\|type-VI-secretion-system-protein-TssL	gnl\|CDD\|180801	PRK07033, PRK07033, DotU family type VI secretion system protein.	1.33611e-128
NZ_CP027665.1\|WP_106471992.1\|1627094_1629284_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.45269e-71
NZ_CP027665.1\|WP_106471997.1\|1635681_1637022_-\|type-VI-secretion-system-baseplate-subunit-TssK	gnl\|CDD\|377569	pfam05936, T6SS_VasE, Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE. T6SS_VasE is a family of of bacterial proteins that are essential for the type VI pathogenic secretion system, although the exact function of this particular component of the system is still not known.	0
NZ_CP027665.1\|WP_106471999.1\|1638575_1638881_-\|hypothetical-protein	gnl\|CDD\|269823	cd14738, PAAR_2, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	8.42533e-14
NZ_CP027665.1\|WP_106472008.1\|1653477_1653981_-\|type-VI-secretion-system-tube-protein-Hcp	gnl\|CDD\|377536	pfam05638, T6SS_HCP, Type VI secretion system effector, Hcp. HCP is a family of proteins which are expressed in up to 1000 copies in Gram-negative bacteria. Together these copies aggregate into a needle-like shaft or tube that will penetrate other bacteria via a puncturing protein attached to its head. Initially Hcp forms a hexameric structure with a central channel of 40 Angstroms. These hexamers pile up one on top of each other forming nanotubes resembling the gp19 tail phage tube.	2.00304e-23
NZ_CP027665.1\|WP_106471993.1\|1629287_1630010_-\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.9695e-60
NZ_CP027665.1\|WP_106471998.1\|1637043_1638567_-\|type-VI-secretion-system-associated-FHA-domain-protein-TagH	gnl\|CDD\|225987	COG3456, COG3456, Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular transport; Signal transduction mechanisms].	4.41287e-54
NZ_CP027665.1\|WP_106472007.1\|1652080_1652575_-\|type-VI-secretion-system-baseplate-subunit-TssE	gnl\|CDD\|226049	COG3518, COG3518, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	4.16159e-30
NZ_CP027665.1\|WP_106471994.1\|1630006_1630687_-\|type-VI-secretion-system-associated-protein-TagF	gnl\|CDD\|370730	pfam09867, DUF2094, Uncharacterized protein conserved in bacteria (DUF2094). This domain, found in various hypothetical prokaryotic proteins, has no known function.	4.50518e-41
NZ_CP027665.1\|WP_106472006.1\|1650198_1652076_-\|type-VI-secretion-system-baseplate-subunit-TssF	gnl\|CDD\|377574	pfam05947, T6SS_TssF, Type VI secretion system, TssF. This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssF. TssF is homologs to phage tail proteins and is required for proper assembly of the Hcp tube (the T6SS inner tube) in bacteria.	0
NZ_CP027665.1\|WP_106472009.1\|1654047_1655547_-\|type-VI-secretion-system-contractile-sheath-large-subunit	gnl\|CDD\|226048	COG3517, COG3517, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	0
NZ_CP027665.1\|WP_106472003.1\|1645523_1646378_-\|ion-transporter	gnl\|CDD\|366146	pfam00520, Ion_trans, Ion transport protein. This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.	8.74293e-32
NZ_CP027665.1\|WP_106471995.1\|1630686_1634253_-\|type-VI-secretion-system-membrane-subunit-TssM	gnl\|CDD\|274531	TIGR03348, VI_IcmF, type VI secretion protein IcmF. Members of this protein family are IcmF homologs and tend to be associated with type VI secretion systems. [Cellular processes, Pathogenesis].	0
NZ_CP027665.1\|WP_106472001.1\|1639497_1641663_-\|type-VI-secretion-system-tip-protein-VgrG	gnl\|CDD\|274542	TIGR03361, VI_Rhs_Vgr, type VI secretion system Vgr family protein. Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.	0
NZ_CP027665.1\|WP_106472004.1\|1646436_1649142_-\|type-VI-secretion-system-ATPase-TssH	gnl\|CDD\|274528	TIGR03345, VI_ClpV1, type VI secretion ATPase, ClpV1 family. Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP027665.1\|WP_106472005.1\|1649176_1650235_-\|type-VI-secretion-system-baseplate-subunit-TssG	gnl\|CDD\|377755	pfam06996, T6SS_TssG, Type VI secretion, TssG. This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssG. TssG is homologs to phage tail proteins and is required for proper assembly of the Hcp tube in bacteria.One other member in this family, SciB (Q93IT4) from Salmonella enterica, is thought to be involved in virulence.	1.37033e-113
NZ_CP027665.1\|WP_106472011.1\|1656134_1657202_-\|type-VI-secretion-system-protein-TssA	gnl\|CDD\|274544	TIGR03363, VI_chp_8, type VI secretion-associated protein, ImpA family. This protein family is one of two related families in type VI secretion systems that contain an ImpA-related N-terminal domain (pfam06812).	2.31216e-62
NZ_CP027665.1\|WP_106472010.1\|1655550_1656072_-\|type-VI-secretion-system-contractile-sheath-small-subunit	gnl\|CDD\|377529	pfam05591, T6SS_VipA, Type VI secretion system, VipA, VC_A0107 or Hcp2. VipA is a family of Gram-negative bacterial proteins that form part of the type VI pathogenic secretion system. Members have been variously defined as VC_A0107 family, Hcp2 and VipA, for ClpV-interacting proteins. VipB and VipA proteins interact very closely to form the shaft of the pathogenic penetrating needle system.	1.67976e-81

>NZ_CP027665.1|WP_106472001.1|1639497_1641663_-|type-VI-secretion-system-tip-protein-VgrG
MPVSKATDYSVVWMSGDYVSEDLMLHSAIVDEGISKLTRARVLFMSKSPDIDLDEFLGRAMRLHVQTEGEAERVITGICTSVEHLGFQGTYDFYTAEFRPKLWLLTRTSDCRVFQNKTAVEIIKQVMDEAGLTDYTDSLTGTYETRTYCLQYRESDFSFISRLMEEEGIYYLFRNALDSTSPENMILCDALSAHEDCPERSEFKYLPLKNKERVYEDAIAEWAVSGEMRRGKVTLADFDFEAPSADTTVVQQIQSGGNPHNSSEVYEYPGRYRNVSALGNARAQVRMEADAARYAQMRGTGMIRTLCAGGKMSFALRDGTEYSPKVEGYVGDYIVTQATHYFMEEFSFQGGGKRGRERGGDARTASRSGRDTKDGDEPKVLMPRNWDFPDEIKDMPFPVFTRFGAIPEAVQYRAPLTTPWPRVTGLQTATVVGQNGEEIWTDEHGRIKIQFHWDREGKDDENSSCWVRVVTPWSGKEWGFVAVPRMGQEVVIQFEEGDPDRPICTGMLYNADTMPPYTYPQDATQLGIKTQSSKDAEGYNELMFDDKAGEELMRVQAQKDHQVLIKNKSVVTVGLDEVNAGDHDEDGSVSRVVRNHVTETIQEGDHYFTISTGNQEIDIATDRTQTIGGNHTKTVTGNDDTTVEQGDLTIGVSSGSIAIEAAMEITLTVGGSSITIDNSGVTISAPMVTISADGMAEMSGTTTTVKGDTLLTLKGGVTKIN
>NZ_CP027665.1|WP_106472000.1|1638877_1639489_-|hypothetical-protein
MSERFKNMVKVPDQPAAKLLARANIRLKTRLDAPASASAEAVLEELDGKKAMIDMLLLMSVLLPPRERVWWACLAARDYIGPKSDKDPPSLAASEIWVFKPTEENRNAARNTLDHAYVDDDTVNCATAVLYADGTLGPGDLKEFPAPAGAAEAAVFTMNMVALKHLSARFEAHGQLLIDRAVDIARGGSGRVEAKVAQEEAGT
>NZ_CP027665.1|WP_106471999.1|1638575_1638881_-|hypothetical-protein
MTRPQARVSDQVLCAMFSVTPAGVTVPGTSAIIPPCAPTVLVGNLPAARIGDLHPSGTGPHPNVSSSATVIIQNMPACRVGDSTACGGAITKGDFTVLTGG
>NZ_CP027665.1|WP_106471998.1|1637043_1638567_-|type-VI-secretion-system-associated-FHA-domain-protein-TagH
MPVTLKFQSSGTMPGNARPIQMQGGSLTVGRGPANDLVLPDPDRTLSKSHCVIEDHNGNIVIVDLSSNGTFLNYSKIPLGRTPTPLNNGDVLALGSYELLVEISDDLPDIDDLIAAPAAQGSVSPGRAENAPDPMALLDDAGPEGDFLDDLLGGSNKPTGPSQLNPVDPIDELLPPIGDEEDPFFGKPDDGRGDGPAQPMHNPSGQDAFSPQGTGQGAGQSLIPEDWDDDFLNPDPPAAAPPPQPSVVPAPQSETPPGNPPENQPEPPADPDAEPTTVPAAAERPDPPSRGATPPSAAEREAAQPAAPQPAATGDDALLRAFLEALGAEGVQLADEDPARTMARMGRVMKTLVTGMREILMTRTSIKSEFRIEQTMISAGGNNPLKFSVSPEQAIEAMVKPAARGYLGPESAAEQALDDIKAHEVAMLTGMEAALRGVLLKLDPEVLAGRIETSGALGSLLKGKKARYWEVYEKMYADISDQAENDFHDLFSREFARAYSEQLQKLK
>NZ_CP027665.1|WP_106471997.1|1635681_1637022_-|type-VI-secretion-system-baseplate-subunit-TssK
MSWDSKVLWTEGLFLQPHHFQQSERYTEALVTGLARRIRPYAWGLSALELDDEVLKVGQIALKSCAGLTQDGTVFRVPSSDDHPPALEVPETIKDCIVYLTVPQRRQGAVEVDLSGAEMSASRLRPSELEVTDTMGRDRKPTTLAVGKTRLQFALAVDDLADRLAIPVARIIEVRPDKEIVLDQAFIPSCLDIRAAAPLDGFLRELEGLLSHRMQALAGRLSESGGARGVAEVSDFLLLTIINRMLPVVRHLTTIENLHPEDLFRTCAALAGELSVFMTADKYPPELPPYRHDDLTRSFTPLIRVLRQYLSSVLEQTAIPIALEARKYGISVGVIADRKLLGNAGFVLAVDADMPSEDVRRHFAGQAKIGPVEEIRQLVNSALPGITLRPLPVAPRQIPYHAGVVYFEMDADSPYWSKMTTSGGIAVHVSGQYPGLKMELWAIRNS
>NZ_CP027665.1|WP_106471996.1|1634249_1635665_-|type-VI-secretion-system-protein-TssL
MIDDDPFAEPDDTDKTVIKPNPGGRLSATPAQPAAAPQPSAPAEPAAPAEDAFGVPQSAAAPQDRRSGAKAPAIAMTGMNRLIACASPLFSLISRIRNRAQHMDPEKLRQSVVAEVRAFENRALQAGIPAQTVKVARYALCATLDDVVLNTPWGGQSSWGLQSMVGTFHRETVGGDRFYDLLARLEKEPGNNIDLLEFLYMCMSLGFEGRLRVEQGGSEKHQQIRAALARIIRAQRGPLEHDLSPHWEGVTKPFKALSAWRVVWIALGVTAGLLVAEFLGLSWALSRTTERVVGQLSVIDSGPVAELQRRAPPPPPTPATPTAEQQLLKVEGFLQEEIDEGIVEVFRKGNTLIIRVAGTGMFGSGSDTLQKDFVARIDRVAKSLNDEPGPVIVVGHSDNVPIRSSRFPSNMALSLARARSVMEGMARVMDDPSRLSAEGRADKEPIADNATRDGRAKNRRIEVLLVQEGDG
>NZ_CP027665.1|WP_106471995.1|1630686_1634253_-|type-VI-secretion-system-membrane-subunit-TssM
MKAVLKVLGSIYFALFFAALVLSLCVWFFAPFIGWGEFRPFDGILSRLITIGVLWLIFGLIMLIIFLRRRKRDKEMAEEIAEVAEAAAPEDDIAAEELGELKSKFRDAITALRKSKNGRRHLNELPWYVMIGPPGAGKTTAIVNSGLQFPLAAEMGKSAIGGVGGTRNCDWWFTNEAVLIDTAGRYTTQESDAETDNAAWLGFLSLLKKYRKRQPINGAMVAISLSDLCLQDEITQKAHAEAVRRRLNELRERLGVRFPVYVLFTKADLIAGFAEFFDHLGKEEREQVWGFTLPVDSGKGEASPVAGFDDEFAQLLGQLNAQSLERMQAETDHQKRALIAGFPAQVASMRGVARDFLNEVFQENRYQHRHALRGVYFTSGTQEGTPIDRLMLGMAQTFGIGRQAVGSGQGSGRSYFLTRLLETVIFNEAGLVSADDKVERRYRWTRRAAIAATVLIALATGAIWVRSYLGNTELLAAAEDHVSQYQAAAATLPPSPVGDTDLPPVVQALNILRDMPGNPVLDDPAPEGRLRYGLYQGEVVGTQAAQTYRAALNQRFLPRLLLRLEEQIGANVNNPDLLYEALKIYLMLGLQGPMNADLVKEWMQLDWSLAYPGVARQDLRADLASHLDALLSQPMQEVALNGPMVEQVQGILSEMPLAQRVYNGIINSATATALPKWRITEAGGPAVSRALVRSSGKPLNEGIEGIFTYDGFNNVFLPEAVSVAGRVQRESWVLGPRGEAEQTEGALLQLSRDVLDLYYNDYIARYDGILGDIDIMPMESLSHAAEITNVLSGPTSPIRNLLTEISNETKLTEDRSLLETDSLESGAKTVLSIEARQQLSIQSQIILEALTSAAAANTGEPPRPPGYYVEERFRWLHELVARPEGQPSQLDDLLGVLTDVYKQLNSMSFSGVTSSEASGEAIAQFQQVASRIDGPMERWSKQIIAGSSGIAADGTRASINARWQSSVLPFCEKALTDRYPFNRRARADVAMADFSKLFAPGGLIDGFFNDNLLKFVDTRSRPWTWKRVNDVDLGISPSVLQQMQYAAEIKDTFFGGSPHAAVKFQITPEALDPKAKSVLLEIDGQQVPFQHRAQPNPVAVTWPGTVGMARVTFAPDKRNLESQVSRDGPWAWFRLLDAAEVRKTNASDRKRVIFNIGGRIAIFQLQSGSVLNPFALPALAKFSCPKSM
>NZ_CP027665.1|WP_106471994.1|1630006_1630687_-|type-VI-secretion-system-associated-protein-TagF
MEAGFGAFGKMPAVGDFFRLSPPKGFVAVWDDWVQQTLLAAQSAFGPDWDAHYMSAPIWRFSLSPGLAGPRKAQGVLMPSVDRVGRRFPLTLVAGLPGPGPAALDHFADAGLFARLEDVALAALDDGMTRDRLAEDLAQVPVPGPRDCAPLRAAARGLVMTQPGPGGLLPDLAADLLAARTDRPSLWSAVIGGVPRLMICEGLPQGDEALGLFSLTAPIWSEARPI
>NZ_CP027665.1|WP_106471993.1|1629287_1630010_-|serine/threonine-protein-phosphatase
MTGPARFRYNAKTHVGLRRKVNEDSVLALPGHDIWLVSDGMGGHDAGDFASRLVADSVAMIPAGLDPTARMHALRDAIRAAHGAIQAEAAARGGNTIGATVVALMIANGHFVGLWAGDSRLYRLRAGEIEMLTTDHSVVAGLVLAGQMSWDEAENHPQSNAITRAVGIGDDFELDKIRGQIRPGDRFLLCSDGLTKYAGVATLARMLGSLPLETVTDELVQLALAGGGADNISVIVVDVI
>NZ_CP027665.1|WP_106471992.1|1627094_1629284_+|protein-kinase
MIDSRPGDAFQPGDLVNNTYRIESLLGRGGTSDVYKARSEISGRLVALKVLKAEFSGNDDYLVLLTREEGIREVRHDAVVRYSENHRTEHGLVYLVMDYVEGPALDRKLKQGPMPADEILTVCRRVAEGLQAAHDRNIVHRDLSPDNIILRDGDPAQAVIIDFGIAKDTNPGAETIVGNEFAGKYAYAAPEQLSGNTDARTDIYSLGALLLANFRGASPDIGNSPMEVVTRKAEPLNTEGVPEPLKTLIDRMTAPEPENRMQSAAEVLAFLDAPDAAPPAAPSDGGADPDATVIVPRARNADAPAATVAPAPDPRDKPAPASRGETRSRGGLFAMLAVVVLIAAGAGAWFSGALDGLLGPKYPIADPYTLIAEKRDGDGVNLTGHAPSEDALAALAGFAETGLGTSELQLASGDIPDSWGADVLALLRDMDGLNAWRVVVDGSSVDITGSTADKALQERLSAALASGLPGALTGRAEITLVPQFLAPDEVQAELDGLADCGPLTLPGVPQLGYGPQSAITVTGKVAGTATRVQLFDGLRDLAGDRNVVVDVEVLNPTLCLIESHLPTAPAGGIAIGFTVGDRDEPNPSGRFFVGENPVIDLTLPADVTDGYLSVSILDVSGNVFHLLPNINRQDNAVAGLRGGRDGDVTVRVAYPVADAGPGQIAFTVDDSTLGKSKILVLHSTAPLFDGMRPTSESAKGYAEALQAHAGVNGTRILSLDSRILETAKP
>NZ_CP027665.1|WP_106472003.1|1645523_1646378_-|ion-transporter
METSNQTGTLTLRARARDFIERPKVTNAILAVIIFNAVTLGLSTSQTMQDSIGGLLTVIDRVVLTIFVVELLIKFYAYGLRFFNSAWNIFDLVVVSVGLLPDKSGLSALRGLRVIRSLRLLSVIPQMRAVVQALLDALPGMGAVIIMISIIFYVFGVMATLMYGAAFDEWFGTLGRSLYSLFQIMTLESWSMGIVRPVMAEFPTAWAFFVPFIVITAFSVLNLFIGLLVNTMQSAVEAEAEAEFEQLRELVKSETDVVDEHVMELHGEIRALRAEVAALKDGRR
>NZ_CP027665.1|WP_106472004.1|1646436_1649142_-|type-VI-secretion-system-ATPase-TssH
MTEISRVALFGKLNRLGYQAVEGATVFCKMRGNPYVEVVHWLHQILNGQDSDLHRIIGHYDLDPGKIAAEMTRALDALPRGASTISDLSDHLMDAMERGWVWGSLLFSDSKVRTGYLLLGMLKTPALRNILNSMSPELGRIGPDDLADHFGEATDGSPEETLGAQDGTTVGGGAEPGEASGAMAPGAMGKGEALEQFCTDLTAQARAGEIDPIVGRDEEIRQIVDVLMRRRQNNPILTGEAGVGKTAVVEGFALRIARGDVPPALKDVRLLVLDVGLLQAGASMKGEFENRLRQVIDEVQASPTPIVMFVDETHTLVGAGGAAGTGDAANLLKPALARGTLRTIGATTWAEYKKYIEKDPALTRRFQVVHVEEPGIPKAVLMMRGIASMLEKHHQVQVLDEGIEAAVTLSARYIPARQLPDKSVSLLDTACARVAVSQHAVPAEVDDSRRRIEALTTELEIIDRDETAGYDVADRRVAVTAAKEAEETRLEGLTDRWDREKAVVEGILDLRAKLREGGTPVEAEPGSEEAEASPLSDEDRGRLLDELRAKNAELAEVQGDSPLILPIVDHQAVASVVGDWTGIPVGRMVKDEIETILNLDERLAQRVIGQDHAMKMIAKRVQTSRAGLDNPNKPIGVFLLAGTSGVGKTETALALAEVLYGGEQNVITINMSEYQEAHTVSSLKGAPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVHEIFFQVFDKGVMEDGEGRLIDFKNTLILLTSNVGTEMIMDLCADPDLMPDPEGIAKALRDPLLKVFPPALLGRLVTIPYYPLSPHMIAEITKLQLGRIKKRVTEAHGVPFDYTDAVVDEIVNRCQELESGGRMIDAIVTNTMLPDISAEFLRRMMEGHEVSKVVIDVTDGEFTYGFD
>NZ_CP027665.1|WP_106472005.1|1649176_1650235_-|type-VI-secretion-system-baseplate-subunit-TssG
MAAGTGPGSDDLRPGQLSLAERLEREPEKHHVFQALRILEAMHPETPRLGESRRPRQDPVRLGQEAETAFPPSTVAAFRPGEGGGPARLTNRFFGLFGPNGPLPLHLTAYARDRQRNHRDPTFLAFANMFTHRMMSLLYRAWASGQPAVSHDRGEDPVADKVAALAGFHGAGLRNRDAMPDLARLHFAGLLAPGPRHAEGLVSILSAFFDVPVRVQQFVGCWLDLEPDDRWQLGARTGLGQSTSIGQRVWSRAAKFRIRIGPLGLRDYERLLPGSGALERLRAIVRTYAGDELDWDVNLILAGDEVPRARLDGTTRLGHTGWIGGRLGGDDDRPDAEDLFLHPGLNGTAAQP
>NZ_CP027665.1|WP_106472006.1|1650198_1652076_-|type-VI-secretion-system-baseplate-subunit-TssF
MDTRLMKHYESELLFLRDMGAEFAAAYPKVASRLGMEGVEVLDPYVERLLEGVAFLSARVQLELELQYPSFTSNLLEIVYPHYLAPTPSMMIAAFEPDASNSAVKSGYVLPRQSVVRSRLMEGEQTPCEFRTAADLTLWAVEIEQAEYIDGRGELVAAGVAGAEGARAGVRLRLRRKDGGPIRDLPMDRLTLFLGGAAGNSWALLELLCTQGIGICGRSTDRRADWVERLEGWGIEHKGFGKDEALLPPTRRVFDGYRLLQEYFAMPERFLFVELQGLKPALKRATGPDVDLYVLLGEGRRDIASMVVPDAFTLNAVPAVNLFPKRCDRVHVTARDTEQHVLPSRTAGLDYEIYRIERVTGITGGGGDDVEFRPFYSTTDFTAAGEIHPAYYTLRRRMRQRSEKERLRGVRTSYLGSEVFLTLVDRRQAPYSAALDQLAVSALCTNRDLPLLLATGNEDVFQLPEGGPVRKIRLPVTPTRPHPTLAQGDTAWRLISHLSLNYLSIADGGNGDAAEALRELVGLYAPIGNRVTEKQLEGLVSVASRPIVRRMSDEVLSTALRGTEITIGFDDSFFEGSSVYVLGAVLERFFRRYATLNSFTETVLTTQTRGEIARWRPERGLGRMI
>NZ_CP027665.1|WP_106472007.1|1652080_1652575_-|type-VI-secretion-system-baseplate-subunit-TssE
MADKTIAERLQPSLLDRLTDDAPGNPKETRESRVIDLSRLRDIIQRDLSWLLNTSNIDNMIDAKAMPNVAKSVLNYGLTEVSGEFSTRERAEAIRRSIQRAVMLYEPRIMRGTVEVTLSADDSNDMTVALEIRADMWAQPMPLELYLRSKVDVTTGEVQVERSY
>NZ_CP027665.1|WP_106474015.1|1652567_1653389_-|virulence-protein-SciE-type
MVSPGPEDHLKSGDLDATLAALQDKVRADPSDARLRIFLFQLLCVLGDWKRAITQLKLAAEMDEAATMMAKTYREAIICEVYREKVFAGEKEPLIFGEPQEWLALLIEAQKVLAGGNPQGAADLRARAFDAAPATPGMINGEPFDWIADADMRLGPVLEAVINGRYFWLPFSAISALECEAPSDLRDAVWTAGMLTLANGGEVAALIPTRYAGTTATGDHAALLARATTWADAGADTFTGCGQRLLATDKSDVALMDIRSLTITGATAGQGDG
>NZ_CP027665.1|WP_106472008.1|1653477_1653981_-|type-VI-secretion-system-tube-protein-Hcp
MENTYVFIKGIDGESLEVGHPKWIPVKTITWDVKRTLDMTDLGTAQRGYANTAFNQIKMTSELSLHSTKLMLSVADGTPHKEIKIEMCRAGDSKGKGMEPYLIFKLSDSVIDEYEVSGGEEQIPEETWSIAYRHISIEYMKADPKSGALSKGGTFDWDVMTGQQGSA
>NZ_CP027665.1|WP_106472009.1|1654047_1655547_-|type-VI-secretion-system-contractile-sheath-large-subunit
MAEEQAQAEAGAEQTAFGSSEFEALLQKEFRPKSDQAKTAVESAVKTLAEQALARTDLISDDALRSIESIVAEIDKKLTEQVNLILHNPEFQQLESAWRGLHYLVNNTETDEMLKIRVMNISKKDMHKTLRKFKGTAWDQSPIFKKLYTEEFSQLGGEPYGSLVADYHFDHSPPDVELLGEMSKIAAAAHAPLITGAKPELFQMDSWSELSNPRDLTKIFQTPEYAAWRSLRESEDSKYVGLAMPRFLGRLPYGSKTDPVEEFAFEEDTEGADSNKYAWVNAAYGMATNITRSFKEFGWCSRIRGVESGGSLEGLPSHTFPTTDGGVDQKCPTEIAIDDRREAELAKNGMMPLIHRKNTDVATFIGAQSLHKPAEYDDPDATANANLAARLPYLFATCRFAHYLKCMVRDKVGSFKSRNDMEKWLQDWIDNYVDFNADVSSEREKSRKPLAAAEVVVEEVEGNPGYYSSKFYLRPHYQLEGLSVSLRLVSKLPSEKGGG
>NZ_CP027665.1|WP_106472010.1|1655550_1656072_-|type-VI-secretion-system-contractile-sheath-small-subunit
MADSSQKFIARNRAPRVQIEYDVELYGAEKKVQLPFVMGVMSDLAGKSEVEQPAVADRKFLEIDVDNFDERMKSMAPRAAFTVPNTLTGEGNLAVDITFESMDDFSPAAIARKVEPLRELLDARSQLSNLMTYMDGKTGAEELIGKIIQDPALLKTLAAQAAPKADDGAEEQE
>NZ_CP027665.1|WP_106472011.1|1656134_1657202_-|type-VI-secretion-system-protein-TssA
MNLEGFLQPMDEGSPSGENLEYDPVFMELELAAQPKEGTEMGNAVTEAEPPDYREMSKKAQEVLERSHDLRAAVYLADAALNMDGMAGFAEVTSYIRGCLEQYWDSCHPELDEDDDDDPTMRINTIQGLCGQPDGLGGPSPVFRSLRRAALTNSRGLGIFSMRDIDLATGQIPVPEGADAPDMTTITGAFRDTDGDWLAGTLAAARQANDDVRAISAVFDEQTPGQGPELDPLIKLLYRINQTLGEHAGGADPAPEGEAAPDAAALAPAAANAAAPAGGGGGAVGAINTPADVSNALDRIVDYYRRSEPSSPVPVLLERAKRLVNADFLTIVKDMAPEGLENVNLIGGIVEEEEY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 22368

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470571.1\|1533_1839_-	hypothetical protein	NA	NA	NA	NA
WP_106470572.1\|1873_2419_-	sarcosine oxidase subunit gamma	NA	NA	NA	NA
WP_106470573.1\|2411_5342_-	sarcosine oxidase subunit alpha family protein	NA	NA	NA	NA
WP_106470574.1\|5338_5602_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_106473856.1\|5731_6985_-	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_106473857.1\|7126_8557_-	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_149615423.1\|8811_10230_+	pilus assembly protein	NA	NA	NA	NA
WP_106470576.1\|10229_10793_+	pilus assembly protein	NA	NA	NA	NA
WP_106470577.1\|10793_11339_+	hypothetical protein	NA	NA	NA	NA
WP_106473858.1\|11317_11839_-	hypothetical protein	NA	NA	NA	NA
WP_106470578.1\|11972_12269_+	hypothetical protein	NA	NA	NA	NA
WP_106470579.1\|12272_12860_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_106470580.1\|13390_14677_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_106470581.1\|14714_15689_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_106470582.1\|15793_17539_+	single-stranded-DNA-specific exonuclease RecJ	NA	NA	NA	NA
WP_106470583.1\|18208_18787_+	DedA family protein	NA	NA	NA	NA
WP_106470584.1\|18783_19245_+	disulfide bond formation protein B	NA	NA	NA	NA
WP_106473859.1\|19285_19720_-	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_106473860.1\|19824_20250_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_106473861.1\|20369_21296_+	arginase	A0A1V0SJM8	Klosneuvirus	3.7e-23	33.0
WP_106470585.1\|21309_22368_+	ornithine cyclodeaminase	A0A1V0SL93	Klosneuvirus	1.9e-87	49.4

DBSCAN-SWA_2

25511 : 27074

Organic_Lake_phycodnavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470588.1\|25511_27074_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.3e-09	28.1

DBSCAN-SWA_3

33414 : 34791

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470596.1\|33414_34500_+	molybdenum ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.4e-21	34.7
WP_106473863.1\|34533_34791_-	DUF2312 domain-containing protein	A0A1X9HX62	Ruegeria_phage	4.3e-30	89.9

DBSCAN-SWA_4

38905 : 39664

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470600.1\|38905_39664_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	3.1e-12	26.2

DBSCAN-SWA_5

42882 : 46301

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470604.1\|42882_45564_-	sodium:solute symporter	W8CYF6	Bacillus_phage	1.4e-14	28.5
WP_106473866.1\|45560_45857_-	hypothetical protein	NA	NA	NA	NA
WP_106470605.1\|45920_46301_-	response regulator	W8CYM9	Bacillus_phage	2.8e-14	34.2

DBSCAN-SWA_6

51669 : 52425

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470610.1\|51669_52425_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	5.3e-12	25.6

DBSCAN-SWA_7

56573 : 59395

Anomala_cuprea_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470615.1\|56573_58439_+	dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.2e-11	23.3
WP_106473867.1\|58435_59395_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.8e-17	30.9

DBSCAN-SWA_8

62603 : 63356

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470620.1\|62603_63356_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.6e-30	38.8

DBSCAN-SWA_9

79347 : 83685

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470638.1\|79347_81090_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.8e-29	25.9
WP_106470639.1\|81086_81719_+	hypothetical protein	NA	NA	NA	NA
WP_106470640.1\|81963_83685_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.1e-31	31.0

DBSCAN-SWA_10

89488 : 93912

Tupanvirus(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470646.1\|89488_90241_-	ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	2.3e-15	30.2
WP_106470647.1\|90237_90735_-	transcriptional repressor	NA	NA	NA	NA
WP_106473870.1\|90895_91747_+	zinc ABC transporter solute-binding protein	NA	NA	NA	NA
WP_106470648.1\|91860_92493_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	1.7e-56	56.3
WP_106470649.1\|92643_93912_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.3e-132	56.3

DBSCAN-SWA_11

97255 : 98326

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470655.1\|97255_98326_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	V5UTY8	Synechococcus_phage	2.4e-10	37.7

DBSCAN-SWA_12

112441 : 115665

Halovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473871.1\|112441_113041_+	Rhs element Vgr protein	R4T6M7	Halovirus	1.5e-09	27.3
WP_106470667.1\|113053_113449_+	hypothetical protein	NA	NA	NA	NA
WP_106470668.1\|113452_113929_+	hypothetical protein	G9J1Z4	Bacillus_phage	3.2e-07	34.9
WP_106470669.1\|113925_115665_+	hypothetical protein	Q8V6M5	Halorubrum_phage	6.3e-16	36.2

DBSCAN-SWA_13

133092 : 139345

uncultured_Mediterranean_phage(80.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470682.1\|133092_133707_-	heme ABC exporter ATP-binding protein CcmA	G9BWD6	Planktothrix_phage	9.9e-09	28.9
WP_106470683.1\|133792_134146_-	hypothetical protein	NA	NA	NA	NA
WP_106473877.1\|134147_134903_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_106470684.1\|134930_135899_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	6.5e-63	50.9
WP_106470685.1\|135900_137562_-	protein translocase subunit SecD	A0A1B1IVP7	uncultured_Mediterranean_phage	3.3e-06	22.9
WP_106470686.1\|137595_137880_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	4.3e-23	59.6
WP_106470687.1\|138052_139345_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.9e-82	43.2

DBSCAN-SWA_14

150704 : 154514

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470696.1\|150704_152516_-	ABC transporter ATP-binding protein/permease	W8CYL7	Bacillus_phage	4.6e-46	30.1
WP_106470697.1\|152525_153854_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_106470698.1\|153962_154514_+	TIGR00730 family Rossman fold protein	A0A2I2L3F0	Orpheovirus	4.4e-08	26.6

DBSCAN-SWA_15

197735 : 200513

Salicola_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473882.1\|197735_200513_-	disulfide oxidoreductase	A0A248SJQ0	Salicola_phage	2.4e-17	32.3

DBSCAN-SWA_16

206088 : 206358

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473885.1\|206088_206358_-	DksA/TraR family C4-type zinc finger protein	A0A193GYU8	Escherichia_phage	6.5e-13	45.1

DBSCAN-SWA_17

214851 : 218214

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470750.1\|214851_215877_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	4.6e-35	35.4
WP_106470751.1\|215873_217055_-	cystathionine gamma-synthase	A0A2I2L687	Orpheovirus	1.1e-06	29.1
WP_106470752.1\|217054_217576_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_106470753.1\|217572_218214_-	guanylate kinase	A0A0M5KCK5	Mollivirus	5.0e-11	39.6

DBSCAN-SWA_18

225232 : 231362

Brazilian_cedratvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470759.1\|225232_226015_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.7e-08	24.2
WP_106470760.1\|226111_226939_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.6e-15	25.4
WP_106470761.1\|226942_227953_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_106470762.1\|227949_229251_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_106470763.1\|229300_229636_-	GYD domain-containing protein	NA	NA	NA	NA
WP_106470764.1\|229820_231362_-	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	7.9e-79	43.2

DBSCAN-SWA_19

237905 : 249054

Streptococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470770.1\|237905_239729_+	translational GTPase TypA	A0A1S5SF82	Streptococcus_phage	8.6e-24	45.5
WP_106470771.1\|239762_241382_-	long-chain-fatty-acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.8e-33	26.6
WP_106470772.1\|241495_243115_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_106470773.1\|243129_243801_-	6-phosphogluconolactonase	NA	NA	NA	NA
WP_106470774.1\|243797_245249_-	glucose-6-phosphate dehydrogenase	A0A1D8KIX9	Synechococcus_phage	1.6e-73	37.2
WP_106470775.1\|245392_245683_-	hypothetical protein	NA	NA	NA	NA
WP_106473888.1\|245820_246090_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_106470776.1\|246288_249054_+	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	2.2e-95	32.2

DBSCAN-SWA_20

255302 : 262389

Vibrio_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470782.1\|255302_255983_+	DUF502 domain-containing protein	A0A2I7S9X1	Vibrio_phage	8.2e-12	25.9
WP_106473890.1\|256012_257038_-	patatin	NA	NA	NA	NA
WP_106470783.1\|257146_257920_-	3-hydroxybutyrate dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	1.0e-10	26.8
WP_106470784.1\|258358_260074_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_106470785.1\|260177_260801_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_106470786.1\|260865_262389_+	acyl--CoA ligase	A0A2K9KZV5	Tupanvirus	7.4e-21	23.4

DBSCAN-SWA_21

268252 : 269743

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470794.1\|268252_269743_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.6e-36	29.3

DBSCAN-SWA_22

273352 : 274075

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470799.1\|273352_274075_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.1e-06	25.5

DBSCAN-SWA_23

278491 : 280844

Only_Syngen_Nebraska_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470805.1\|278491_280135_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.0e-152	50.4
WP_106470806.1\|280160_280844_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	9.7e-13	29.4

DBSCAN-SWA_24

307732 : 349379

Klosneuvirus(12.5%)

terminase,transposase,capsid,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470826.1\|307732_309391_-\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	1.4e-57	31.1
WP_106470827.1\|309390_310050_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_106470828.1\|310049_311507_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_106470829.1\|311503_313066_-\|holin	choline-sulfatase	A0A1V0SA98	Catovirus	1.8e-14	23.4
WP_106473897.1\|313062_313632_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_106473898.1\|313736_314597_-	DMT family transporter	NA	NA	NA	NA
WP_106470830.1\|314690_315290_-	amino acid transporter	NA	NA	NA	NA
WP_106470831.1\|315378_316257_+	LysR family transcriptional regulator ArgP	NA	NA	NA	NA
WP_106470832.1\|316355_317048_+	nitroreductase family protein	NA	NA	NA	NA
WP_106470833.1\|317102_317843_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_106470834.1\|317932_319705_+	SLC13 family permease	NA	NA	NA	NA
WP_106470835.1\|319765_320500_+	glutamine amidotransferase	NA	NA	NA	NA
WP_106470836.1\|320601_322260_+	FAD-binding dehydrogenase	NA	NA	NA	NA
WP_106470837.1\|322267_323047_-	META domain-containing protein	NA	NA	NA	NA
WP_106470838.1\|323111_324890_-	SLC13 family permease	NA	NA	NA	NA
WP_106470839.1\|324933_325857_-	DMT family transporter	NA	NA	NA	NA
WP_106470840.1\|325853_326666_-	YmdB family metallophosphoesterase	NA	NA	NA	NA
WP_106470841.1\|326776_327001_+	DUF333 domain-containing protein	NA	NA	NA	NA
WP_106470842.1\|327032_327587_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_106470843.1\|327583_328978_-	magnesium transporter	NA	NA	NA	NA
WP_106470844.1\|329108_330422_+	guanine deaminase	NA	NA	NA	NA
WP_106470845.1\|330431_330749_-	arsenate reductase	NA	NA	NA	NA
WP_106470846.1\|330988_331195_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	1.8e-10	50.0
WP_106473899.1\|331258_332167_-	FAD-dependent thymidylate synthase	M4QT16	Loktanella_phage	2.6e-98	60.8
WP_106473900.1\|332342_332771_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_106473901.1\|332737_333493_+	DUF1194 domain-containing protein	NA	NA	NA	NA
WP_106473902.1\|333489_333981_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_106473903.1\|334044_334272_-	succinate dehydrogenase assembly factor 2	NA	NA	NA	NA
WP_106470847.1\|334307_334709_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_106470848.1\|334815_336018_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_106470849.1\|336025_336436_+	hypothetical protein	NA	NA	NA	NA
WP_106470850.1\|336462_337827_-	MATE family efflux transporter	NA	NA	NA	NA
WP_106470851.1\|338012_338942_-	polyphosphate kinase 2	NA	NA	NA	NA
WP_106470852.1\|339073_339967_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_106470853.1\|339963_340575_+	glutathione S-transferase	NA	NA	NA	NA
WP_106470854.1\|340741_342697_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	1.6e-113	39.2
WP_149615428.1\|344774_344921_-\|transposase	transposase	NA	NA	NA	NA
WP_106470855.1\|345274_346505_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	2.3e-81	57.3
WP_106470856.1\|346747_347254_+	hypothetical protein	NA	NA	NA	NA
WP_106470857.1\|347498_348761_+\|capsid	phage major capsid protein	G8EXZ9	Synechococcus_phage	7.3e-14	27.1
WP_149615429.1\|348980_349379_+\|terminase	P27 family phage terminase small subunit	A0A0U2C0X7	Paracoccus_phage	2.8e-12	40.3

DBSCAN-SWA_25

363084 : 363366

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470873.1\|363084_363366_-	integration host factor subunit beta	A0A0H3UZA0	Geobacillus_virus	4.8e-11	38.6

DBSCAN-SWA_26

366957 : 368313

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470877.1\|366957_368313_-	cytochrome P450	A0A1V0SF03	Hokovirus	2.5e-12	27.6

DBSCAN-SWA_27

378513 : 379272

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470883.1\|378513_379272_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	1.1e-44	40.9

DBSCAN-SWA_28

386674 : 391569

Synechococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470892.1\|386674_387271_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.8e-24	35.6
WP_106470893.1\|387267_388314_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.5e-57	42.0
WP_106470894.1\|388760_389027_+	hypothetical protein	NA	NA	NA	NA
WP_106470895.1\|389028_389700_+	SOS response-associated peptidase	A0A2D1GMM4	Marinobacter_phage	6.8e-11	31.6
WP_106470896.1\|389732_389984_+	hypothetical protein	NA	NA	NA	NA
WP_149615433.1\|390289_390640_+	hypothetical protein	NA	NA	NA	NA
WP_106470897.1\|391260_391569_-	hypothetical protein	A0A1B0T6F7	Thiobacimonas_phage	9.7e-13	40.4

DBSCAN-SWA_29

397718 : 401996

Paracoccus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470907.1\|397718_400904_-	hypothetical protein	A0A0U2C146	Paracoccus_phage	1.2e-129	42.0
WP_106470908.1\|400900_401317_-	hypothetical protein	A0A0U2C0Z1	Paracoccus_phage	2.8e-31	50.0
WP_106470909.1\|401321_401996_-	hypothetical protein	A0A0U2C133	Paracoccus_phage	7.3e-21	33.3

DBSCAN-SWA_30

405990 : 429696

Emiliania_huxleyi_virus(31.25%)

head,tail,protease,terminase,capsid,integrase,portal

attL 413675:413692|attR 433778:433795

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470914.1\|405990_406395_-	hypothetical protein	A0A141GEW6	Brucella_phage	1.6e-23	44.1
WP_106470915.1\|406394_406799_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_106470916.1\|406795_407131_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_106470917.1\|407127_407703_-	hypothetical protein	A0A141GEW4	Brucella_phage	2.8e-37	41.1
WP_106473909.1\|407707_407890_-	hypothetical protein	A0A2H4JDE5	uncultured_Caudovirales_phage	5.7e-05	44.4
WP_106470918.1\|407949_409149_-\|capsid	phage major capsid protein	A0A0U2C0U7	Paracoccus_phage	3.0e-126	61.5
WP_106470919.1\|409182_409857_-\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	1.2e-47	53.3
WP_106473910.1\|409840_410950_-\|portal	phage portal protein	A0A0U2BXP2	Paracoccus_phage	5.6e-119	58.4
WP_106470920.1\|411048_412764_-\|terminase	terminase large subunit	A0A0P0ZEI4	Stx2-converting_phage	1.5e-131	45.7
WP_106473911.1\|412756_413215_-	hypothetical protein	I3ULZ5	Rhodobacter_phage	1.0e-21	42.0
413675:413692	attL	NA	NA	NA	NA
WP_106470921.1\|414277_415081_-	hypothetical protein	NA	NA	NA	NA
WP_106470922.1\|415508_417227_-	hypothetical protein	G8DGC0	Emiliania_huxleyi_virus	3.2e-174	55.1
WP_106470923.1\|417223_417631_-	hypothetical protein	NA	NA	NA	NA
WP_149615440.1\|417630_417846_-	hypothetical protein	NA	NA	NA	NA
WP_106470924.1\|417842_418925_-	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_106470925.1\|419177_419414_-	hypothetical protein	NA	NA	NA	NA
WP_106470926.1\|419406_419628_-	hypothetical protein	NA	NA	NA	NA
WP_106470927.1\|419757_420111_-	hypothetical protein	NA	NA	NA	NA
WP_106470928.1\|420107_420557_-	hypothetical protein	G8DGB3	Emiliania_huxleyi_virus	2.4e-28	51.5
WP_149615441.1\|420711_421599_+	hypothetical protein	NA	NA	NA	NA
WP_106470930.1\|422050_422497_+	hypothetical protein	NA	NA	NA	NA
WP_149615442.1\|422623_422995_+	hypothetical protein	NA	NA	NA	NA
WP_106470932.1\|422994_423210_+	hypothetical protein	G8DH83	Emiliania_huxleyi_virus	5.5e-07	42.0
WP_106470933.1\|423206_423500_+	hypothetical protein	NA	NA	NA	NA
WP_106470934.1\|423496_423763_+	hypothetical protein	NA	NA	NA	NA
WP_106470935.1\|423844_424141_+	hypothetical protein	NA	NA	NA	NA
WP_106470936.1\|424137_424407_+	hypothetical protein	NA	NA	NA	NA
WP_106470937.1\|424399_426454_+	DNA methyltransferase	A0A1X9HVK8	Ruegeria_phage	3.3e-274	72.5
WP_106473912.1\|426594_426798_+	hypothetical protein	G8DH77	Emiliania_huxleyi_virus	1.3e-18	67.2
WP_106470938.1\|427116_427353_+	hypothetical protein	NA	NA	NA	NA
WP_106470939.1\|427349_427589_+	hypothetical protein	NA	NA	NA	NA
WP_106473913.1\|427654_427828_+	helix-turn-helix domain-containing protein	I3UM25	Rhodobacter_phage	7.8e-12	67.3
WP_106470940.1\|427830_428928_+\|integrase	site-specific integrase	G8DH71	Emiliania_huxleyi_virus	3.2e-90	47.2
WP_106470941.1\|429027_429696_-	ATP-binding cassette domain-containing protein	A0A285PWH2	Cedratvirus	1.0e-14	35.0
433778:433795	attR	NA	NA	NA	NA

DBSCAN-SWA_31

433292 : 435443

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473914.1\|433292_435443_-	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.7e-34	25.2

DBSCAN-SWA_32

440842 : 441628

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470948.1\|440842_441628_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.6e-35	38.8

DBSCAN-SWA_33

448689 : 450309

Tetraselmis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470954.1\|448689_450309_-	arylsulfatase	A0A2P0VMN7	Tetraselmis_virus	1.1e-142	49.7

DBSCAN-SWA_34

453368 : 454430

Burkholderia_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615444.1\|453368_454430_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.9e-39	56.1

DBSCAN-SWA_35

464856 : 467955

Klosneuvirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470969.1\|464856_467955_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	9.5e-124	32.8

DBSCAN-SWA_36

472322 : 474179

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470974.1\|472322_474179_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.5e-44	28.1

DBSCAN-SWA_37

490685 : 498518

uncultured_virus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473921.1\|490685_493211_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.2e-92	35.4
WP_106470987.1\|493221_493629_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_106470988.1\|493855_494620_+	hypothetical protein	NA	NA	NA	NA
WP_106470989.1\|494705_497120_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	2.9e-205	49.2
WP_106470990.1\|497387_498518_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.2e-103	53.5

DBSCAN-SWA_38

508456 : 509560

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473923.1\|508456_509560_-	class II histone deacetylase	A0A2K9L473	Tupanvirus	2.2e-22	33.3

DBSCAN-SWA_39

519123 : 521838

Escherichia_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471010.1\|519123_519720_+	thymidine kinase	A8R997	Escherichia_phage	6.4e-53	55.8
WP_106471011.1\|519729_520656_-	D-glycerate dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	5.5e-11	29.9
WP_106471012.1\|520679_521030_-\|tRNA	tRNA-binding protein	NA	NA	NA	NA
WP_106471013.1\|521022_521838_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	8.0e-22	33.1

DBSCAN-SWA_40

525849 : 531048

Rhizobium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471019.1\|525849_526836_+	cobaltochelatase subunit CobS	L7TKP0	Rhizobium_phage	4.5e-35	34.3
WP_149615446.1\|526835_527342_+	hypothetical protein	NA	NA	NA	NA
WP_106471020.1\|527338_529207_+	cobaltochelatase subunit CobT	J9Q7G6	Salmonella_phage	5.3e-13	27.3
WP_106473924.1\|529257_531048_+	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	2.0e-81	33.4

DBSCAN-SWA_41

559081 : 563271

Bacillus_phage(50.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473928.1\|559081_561493_-	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	1.4e-114	37.2
WP_106473929.1\|561645_563271_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	6.6e-52	30.3

DBSCAN-SWA_42

567399 : 568473

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471045.1\|567399_568473_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.8e-21	50.5

DBSCAN-SWA_43

585723 : 587229

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471056.1\|585723_587229_-	histidine ammonia-lyase	A0A1V0S940	Catovirus	6.7e-75	37.4

DBSCAN-SWA_44

595427 : 600340

Erwinia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471064.1\|595427_595889_-	NUDIX hydrolase	A0A2H4IB87	Erwinia_phage	9.4e-12	38.1
WP_106471065.1\|596000_596759_-	EcsC family protein	NA	NA	NA	NA
WP_106473931.1\|596790_597288_-	N-acetyltransferase	NA	NA	NA	NA
WP_106471066.1\|597364_597970_+	flavin reductase family protein	NA	NA	NA	NA
WP_106471067.1\|597969_598608_+	CatB-related O-acetyltransferase	NA	NA	NA	NA
WP_106471068.1\|598711_600340_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	5.6e-91	42.6

DBSCAN-SWA_45

603636 : 604176

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473933.1\|603636_604176_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.4e-29	45.1

DBSCAN-SWA_46

608002 : 609265

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471074.1\|608002_609265_-	insulinase family protein	A0A2K9LA15	Tupanvirus	1.0e-28	26.3

DBSCAN-SWA_47

616635 : 627328

Thermus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471081.1\|616635_617790_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	1.7e-25	42.9
WP_106471082.1\|617972_620525_+	type I DNA topoisomerase	A0A0G2Y787	Acanthamoeba_polyphaga_mimivirus	1.9e-101	31.6
WP_106471083.1\|620564_621161_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_106471084.1\|621226_621652_+	glyoxalase	NA	NA	NA	NA
WP_106471085.1\|621743_622448_+	CoA transferase subunit A	NA	NA	NA	NA
WP_106471086.1\|622447_623089_+	3-oxoacid CoA-transferase subunit B	NA	NA	NA	NA
WP_106471087.1\|623152_623971_-	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	5.4e-18	51.5
WP_106471088.1\|624309_624552_+	hypothetical protein	NA	NA	NA	NA
WP_106471089.1\|624655_624856_+	hypothetical protein	NA	NA	NA	NA
WP_106471090.1\|624886_625744_+	Flp pilus assembly protein CpaB	NA	NA	NA	NA
WP_106471091.1\|625933_627328_+	type II and III secretion system protein family protein	D0U174	Enterobacteria_phage	2.7e-09	24.6

DBSCAN-SWA_48

641616 : 648668

Enterococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473937.1\|641616_642519_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	9.4e-32	39.6
WP_106473938.1\|642566_642872_-	chorismate mutase	NA	NA	NA	NA
WP_106471105.1\|642932_644609_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_106471106.1\|644789_645368_-	sulfurase	NA	NA	NA	NA
WP_106471107.1\|645452_647369_-	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	C7U047	Ostreococcus_tauri_virus	4.3e-119	42.8
WP_106473939.1\|647447_648668_-\|tRNA	tRNA lysidine(34) synthetase TilS	M1HHJ8	Acanthocystis_turfacea_Chlorella_virus	1.6e-10	32.2

DBSCAN-SWA_49

654859 : 655888

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471116.1\|654859_655888_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	1.2e-06	30.3

DBSCAN-SWA_50

659886 : 662032

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473941.1\|659886_660960_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.5e-15	26.5
WP_106471122.1\|660952_662032_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-09	24.9

DBSCAN-SWA_51

666474 : 667182

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471125.1\|666474_667182_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-37	39.1

DBSCAN-SWA_52

674798 : 677237

Synechococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471133.1\|674798_675716_-\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	6.9e-06	27.8
WP_106471134.1\|675719_676223_-	peptide deformylase	NA	NA	NA	NA
WP_106471135.1\|676219_676717_-	peptide deformylase	E3SLL2	Synechococcus_phage	8.0e-17	39.0
WP_106471136.1\|676718_677237_-	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-25	49.2

DBSCAN-SWA_53

699354 : 702125

Geobacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471161.1\|699354_700170_-	glycoside hydrolase family 25 protein	A0A1U9WQS3	Geobacillus_phage	1.2e-20	35.9
WP_106471162.1\|700539_700926_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_106471163.1\|700938_701160_+	50S ribosomal protein L31	NA	NA	NA	NA
WP_106471164.1\|701321_702125_+	P-loop NTPase	D3JZ99	Mycobacterium_phage	1.3e-05	32.9

DBSCAN-SWA_54

710380 : 714103

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471172.1\|710380_711394_+	NAD-dependent epimerase/dehydratase family protein	A0A1V0SAI6	Catovirus	8.4e-29	28.9
WP_106471173.1\|711484_714103_-	ATP-dependent chaperone ClpB	A0A2I7SAX5	Vibrio_phage	9.8e-122	37.7

DBSCAN-SWA_55

726878 : 727898

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471186.1\|726878_727898_+	ribose-phosphate pyrophosphokinase	A0A1V0SHF7	Hokovirus	7.1e-44	33.8

DBSCAN-SWA_56

735407 : 737729

Agrobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471193.1\|735407_737729_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.2e-171	43.8

DBSCAN-SWA_57

752763 : 774996

Mycoplasma_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471205.1\|752763_753849_-	histidinol-phosphate transaminase	A0A1X7BZP2	Faustovirus	7.9e-17	26.8
WP_106471206.1\|753910_754600_-	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_106471207.1\|754596_755685_-	ATP phosphoribosyltransferase regulatory subunit	A0A2K9L6G5	Tupanvirus	3.3e-07	22.4
WP_106471208.1\|755684_757325_-\|tRNA	histidine--tRNA ligase	A0A1V0S921	Catovirus	5.4e-09	31.5
WP_106471209.1\|757405_757867_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_106471210.1\|757977_759405_+	aminotransferase class V-fold PLP-dependent enzyme	A0A1C9C5E2	Heterosigma_akashiwo_virus	5.5e-42	31.2
WP_106471211.1\|759457_759889_-	DUF1489 domain-containing protein	NA	NA	NA	NA
WP_106471212.1\|760019_762503_+	adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	M4QT32	Loktanella_phage	4.3e-284	61.2
WP_106471213.1\|762670_763021_-	RidA family protein	NA	NA	NA	NA
WP_106471214.1\|763037_764138_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_106471215.1\|764134_765163_-	histone deacetylase family protein	A0A2K9L4C2	Tupanvirus	3.1e-31	33.5
WP_106471216.1\|765159_765639_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_106471217.1\|765635_766565_-	3-keto-5-aminohexanoate cleavage protein	A0A1V0SL81	Klosneuvirus	1.8e-17	25.7
WP_106471218.1\|766566_767904_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	1.3e-21	25.3
WP_106471219.1\|767905_768982_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	3.3e-23	51.0
WP_106473950.1\|769036_770173_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_106471220.1\|770223_771015_-	ABC transporter permease	NA	NA	NA	NA
WP_106471221.1\|771014_771881_-	ABC transporter permease	Q6GZ02	Mycoplasma_phage	3.8e-06	25.5
WP_106471222.1\|771976_772957_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_106471223.1\|772981_773989_-	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	1.2e-06	27.0
WP_106471224.1\|773985_774996_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	7.6e-06	30.2

DBSCAN-SWA_58

787926 : 789555

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471236.1\|787926_789555_-	ABC transporter ATP-binding protein	A0A2H4UU96	Bodo_saltans_virus	1.9e-06	25.2

DBSCAN-SWA_59

816709 : 817873

uncultured_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471260.1\|816709_817873_-	signal recognition particle-docking protein FtsY	D6PHS7	uncultured_phage	1.1e-13	34.4

DBSCAN-SWA_60

821655 : 823086

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471265.1\|821655_823086_-	exodeoxyribonuclease VII large subunit	A0A160DF99	Gordonia_phage	1.0e-32	36.0

DBSCAN-SWA_61

826633 : 828055

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471269.1\|826633_828055_-	Do family serine endopeptidase	A0A1B1IT49	uncultured_Mediterranean_phage	5.8e-28	31.1

DBSCAN-SWA_62

837254 : 838547

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471280.1\|837254_838547_-	adenylosuccinate synthase	A0A291AUF9	Pandoravirus	4.0e-52	32.4

DBSCAN-SWA_63

850056 : 856335

Moraxella_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471290.1\|850056_851397_-	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	1.2e-30	31.6
WP_106471291.1\|851539_853063_-	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_106471292.1\|853236_853413_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_106471293.1\|853533_856335_+	DNA polymerase I	A0A0C5K9B9	Enterococcus_phage	4.8e-42	34.7

DBSCAN-SWA_64

874017 : 874566

Agrobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471316.1\|874017_874566_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	1.4e-14	33.3

DBSCAN-SWA_65

892512 : 893532

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471328.1\|892512_893532_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	3.7e-16	35.2

DBSCAN-SWA_66

897029 : 898427

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471333.1\|897029_898427_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	7.8e-17	34.3

DBSCAN-SWA_67

908312 : 909815

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471345.1\|908312_909815_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-15	30.0

DBSCAN-SWA_68

917341 : 918358

Planktothrix_phage(100.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471350.1\|917341_918358_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-28	40.2

DBSCAN-SWA_69

931487 : 933203

Tupanvirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471362.1\|931487_933203_+\|tRNA	methionine--tRNA ligase	A0A2K9KZR3	Tupanvirus	1.1e-81	33.4

DBSCAN-SWA_70

936574 : 937060

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471365.1\|936574_937060_-	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	4.6e-17	37.7

DBSCAN-SWA_71

944829 : 949840

Pandoravirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471373.1\|944829_945525_+	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	1.0e-17	29.9
WP_106471374.1\|945679_947173_+	replicative DNA helicase	A0A077SK18	Escherichia_phage	1.1e-74	37.9
WP_106471375.1\|947283_948318_+	alanine racemase	NA	NA	NA	NA
WP_106471376.1\|948314_949097_+	ABC transporter permease	NA	NA	NA	NA
WP_106471377.1\|949093_949840_+	ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	2.4e-09	27.7

DBSCAN-SWA_72

953236 : 953821

Agrobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471383.1\|953236_953821_-	HNH endonuclease	A0A223W0A5	Agrobacterium_phage	3.9e-31	42.6

DBSCAN-SWA_73

960356 : 973790

uncultured_Mediterranean_phage(57.14%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471391.1\|960356_961724_-\|tRNA	cysteine--tRNA ligase	A0A0G2Y344	Acanthamoeba_polyphaga_mimivirus	6.6e-45	35.0
WP_106471392.1\|962057_963569_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.4e-51	33.3
WP_106471393.1\|963748_964006_+	hypothetical protein	NA	NA	NA	NA
WP_106473960.1\|964070_964727_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_106471394.1\|964805_965588_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.4e-31	34.8
WP_106471395.1\|965584_966232_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	3.8e-27	43.9
WP_106473961.1\|966290_967451_+	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_106471396.1\|967524_967857_+	hypothetical protein	NA	NA	NA	NA
WP_106471397.1\|967863_968709_-	ATP-binding protein	NA	NA	NA	NA
WP_106473962.1\|968914_969985_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.5e-28	35.9
WP_106471398.1\|970083_970929_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_149615457.1\|970938_971325_+	hypothetical protein	NA	NA	NA	NA
WP_106471400.1\|971331_972000_-	HTH domain-containing protein	NA	NA	NA	NA
WP_106471401.1\|972216_972432_+	Sec-independent protein translocase TatA	A0A1B1IVR9	uncultured_Mediterranean_phage	4.0e-05	53.2
WP_106471402.1\|972438_972909_+	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_106471403.1\|972905_973790_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	1.2e-36	37.8

DBSCAN-SWA_74

984565 : 1026321

Burkholderia_virus(14.29%)

transposase,integrase

attL 1014921:1014937|attR 1031265:1031281

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471414.1\|984565_985039_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_106470855.1\|985182_986413_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	2.3e-81	57.3
WP_106471415.1\|987791_989666_-	FkbM family methyltransferase	NA	NA	NA	NA
WP_106471416.1\|989812_990382_-	peroxidase-related enzyme	NA	NA	NA	NA
WP_106471417.1\|990435_991986_-	acetolactate synthase large subunit	NA	NA	NA	NA
WP_106471418.1\|992076_993294_-	CoA transferase	NA	NA	NA	NA
WP_106471419.1\|993290_994067_-	CoA synthetase	NA	NA	NA	NA
WP_106471420.1\|994063_994876_-	CoA synthetase	NA	NA	NA	NA
WP_106471421.1\|994948_996985_-	TRAP transporter fused permease subunit	NA	NA	NA	NA
WP_106471422.1\|997047_998211_-	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_106471423.1\|998261_999305_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_106471424.1\|999372_1000059_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_106471425.1\|1000103_1002296_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_106473963.1\|1002287_1003112_+	TrkA family potassium uptake protein	NA	NA	NA	NA
WP_106471426.1\|1003114_1004464_+	Ktr system potassium transporter B	NA	NA	NA	NA
WP_106471427.1\|1004545_1004857_+	ETC complex I subunit	NA	NA	NA	NA
WP_106471428.1\|1004879_1007225_-	bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase	NA	NA	NA	NA
WP_106473964.1\|1007221_1007653_-	RidA family protein	NA	NA	NA	NA
WP_106471429.1\|1007673_1008363_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.6e-07	24.7
WP_106471430.1\|1008359_1009109_-	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.2e-08	24.4
WP_106471431.1\|1009101_1010085_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_106471432.1\|1010081_1011002_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_106471433.1\|1011056_1012193_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_106471434.1\|1012243_1013731_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_106471435.1\|1013741_1014188_-	cupin domain-containing protein	NA	NA	NA	NA
WP_106471436.1\|1014218_1015835_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	9.2e-46	32.2
1014921:1014937	attL	NA	NA	NA	NA
WP_106471437.1\|1015838_1016285_-	cupin domain-containing protein	NA	NA	NA	NA
WP_106471438.1\|1016322_1017474_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_106471439.1\|1017556_1018360_-	enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_106471440.1\|1018356_1018836_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_106471441.1\|1018832_1019591_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_106473965.1\|1019779_1020916_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_106471442.1\|1021038_1021308_+	hypothetical protein	NA	NA	NA	NA
WP_106471443.1\|1021469_1022558_+\|integrase	site-specific integrase	A0A0A1I5U0	Burkholderia_phage	3.7e-30	38.0
WP_106471444.1\|1022403_1023618_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.8e-39	42.9
WP_149615458.1\|1024376_1024832_+	hypothetical protein	NA	NA	NA	NA
WP_149615459.1\|1024753_1025161_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_106471446.1\|1025149_1026321_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	7.1e-48	38.5
1031265:1031281	attR	NA	NA	NA	NA

DBSCAN-SWA_75

1043574 : 1045200

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471466.1\|1043574_1045200_-	AMP-binding protein	Q75ZG1	Hepacivirus	5.3e-41	27.0

DBSCAN-SWA_76

1052470 : 1053109

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471473.1\|1052470_1053109_-	SOS response-associated peptidase	V9IQW7	Stenotrophomonas_phage	3.7e-22	38.7

DBSCAN-SWA_77

1057590 : 1060440

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471482.1\|1057590_1060440_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	2.0e-80	44.9

DBSCAN-SWA_78

1067873 : 1080756

Ochrobactrum_phage(14.29%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471488.1\|1067873_1068413_-	AAA family ATPase	A0A219VHB7	Ochrobactrum_phage	5.3e-22	58.1
WP_106471489.1\|1068632_1068902_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_106471490.1\|1069145_1070237_-	hypothetical protein	NA	NA	NA	NA
WP_106471491.1\|1070319_1070826_-	DUF1643 domain-containing protein	A0A0U1W068	Pseudomonas_phage	3.9e-27	43.9
WP_106471492.1\|1070822_1071731_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_106471493.1\|1071858_1072491_+	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	1.3e-19	37.1
WP_106471494.1\|1072581_1073688_+	site-specific DNA-methyltransferase	A0A249XUJ2	Enterococcus_phage	2.8e-30	30.5
WP_106471495.1\|1073894_1074344_+	YtoQ family protein	NA	NA	NA	NA
WP_106471496.1\|1074396_1074996_-	HD family hydrolase	A0A0K1Y6I9	Rhodobacter_phage	5.1e-18	45.3
WP_106471497.1\|1075211_1075520_+	hypothetical protein	NA	NA	NA	NA
WP_106471498.1\|1075663_1077058_+	adenosylhomocysteinase	S4VPF6	Pandoravirus	2.9e-40	30.7
WP_106471499.1\|1077390_1077732_+	DUF2853 family protein	NA	NA	NA	NA
WP_106471500.1\|1078009_1078432_-	EVE domain-containing protein	NA	NA	NA	NA
WP_106471501.1\|1078431_1078701_-	YciI family protein	NA	NA	NA	NA
WP_106471502.1\|1078702_1079662_-	NAD(P)-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_106471503.1\|1079658_1080756_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.4e-61	41.7

DBSCAN-SWA_79

1106571 : 1118316

Klosneuvirus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471530.1\|1106571_1107426_-	hydroxymethylglutaryl-CoA lyase	A0A1V0SKU2	Klosneuvirus	3.0e-35	33.3
WP_106471531.1\|1107485_1109423_-	acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha	NA	NA	NA	NA
WP_106471532.1\|1109504_1111109_-	methylcrotonoyl-CoA carboxylase	A0A1B2ITV7	Pike_perch_iridovirus	1.9e-19	52.4
WP_106471533.1\|1111186_1111693_-	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_106471534.1\|1111778_1112942_-	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_106471535.1\|1113048_1114293_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A2K9L0G1	Tupanvirus	8.2e-18	25.1
WP_106471536.1\|1114324_1115011_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_106471537.1\|1115135_1116491_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A0N7G7P8	Chrysochromulina_ericina_virus	1.7e-24	30.5
WP_106471538.1\|1116492_1118316_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	7.8e-102	38.9

DBSCAN-SWA_80

1125561 : 1127382

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471546.1\|1125561_1127382_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.3e-15	30.1

DBSCAN-SWA_81

1140246 : 1141629

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471558.1\|1140246_1141629_+	leucyl aminopeptidase family protein	Q6GYZ8	Mycoplasma_phage	1.4e-31	33.1

DBSCAN-SWA_82

1169549 : 1172797

Hepacivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471585.1\|1169549_1171172_-	AMP-binding protein	Q75ZG1	Hepacivirus	6.2e-34	24.6
WP_106471586.1\|1171180_1172797_-	hypothetical protein	A0A1V0S9M4	Catovirus	5.6e-51	27.8

DBSCAN-SWA_83

1199083 : 1199842

Indivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473974.1\|1199083_1199842_-	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	2.6e-06	21.9

DBSCAN-SWA_84

1205503 : 1270586

Agrobacterium_phage(13.33%)

head,transposase,protease,integrase

attL 1202454:1202470|attR 1270763:1270779

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1202454:1202470	attL	NA	NA	NA	NA
WP_106473975.1\|1205503_1206115_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.9e-28	40.9
WP_106473976.1\|1206147_1207317_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	7.1e-40	32.3
WP_106471619.1\|1208308_1208569_-	hypothetical protein	NA	NA	NA	NA
WP_106471620.1\|1208603_1210040_-	hypothetical protein	J7FA77	Agrobacterium_phage	7.9e-49	37.0
WP_106471621.1\|1210036_1210687_-	hypothetical protein	A0A2I7QS52	Vibrio_phage	3.9e-19	44.5
WP_106471622.1\|1210686_1211103_-	hypothetical protein	NA	NA	NA	NA
WP_106471623.1\|1211099_1211573_-\|head,protease	HK97 family phage prohead protease	J7FAG0	Agrobacterium_phage	5.8e-25	47.9
WP_106471624.1\|1211569_1211815_-	hypothetical protein	NA	NA	NA	NA
WP_149615464.1\|1211801_1212029_-	hypothetical protein	NA	NA	NA	NA
WP_106471626.1\|1213546_1215169_-	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.2e-08	26.0
WP_106471627.1\|1215367_1217164_+	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	9.3e-55	35.8
WP_106471629.1\|1217421_1218846_-	hypothetical protein	NA	NA	NA	NA
WP_106471630.1\|1219070_1220534_-	amidohydrolase	NA	NA	NA	NA
WP_106471631.1\|1220922_1221579_+	CatB-related O-acetyltransferase	M1HKK6	Paramecium_bursaria_Chlorella_virus	3.0e-19	45.2
WP_149615465.1\|1221575_1221899_-	hypothetical protein	NA	NA	NA	NA
WP_106471633.1\|1222041_1222188_+	hypothetical protein	NA	NA	NA	NA
WP_106471634.1\|1223304_1224195_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_106471635.1\|1224316_1226398_+	TonB-dependent receptor	NA	NA	NA	NA
WP_149615466.1\|1226478_1228254_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	3.1e-34	28.4
WP_106471637.1\|1228102_1230004_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.3e-27	42.5
WP_106473977.1\|1229988_1230825_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_106471638.1\|1231788_1232832_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_106471639.1\|1233383_1234367_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_106471640.1\|1234537_1235314_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_106471641.1\|1235406_1236396_+	BMP family protein	NA	NA	NA	NA
WP_106471642.1\|1236459_1237986_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.6e-07	27.4
WP_106471643.1\|1237988_1239098_+	ABC transporter permease	NA	NA	NA	NA
WP_106471644.1\|1239087_1240026_+	ABC transporter permease	NA	NA	NA	NA
WP_106471646.1\|1240827_1241238_+\|transposase	transposase	NA	NA	NA	NA
WP_106471647.1\|1241768_1242023_+	addiction module antitoxin	NA	NA	NA	NA
WP_106471648.1\|1242027_1242345_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_106471649.1\|1242689_1243076_-\|transposase	transposase	NA	NA	NA	NA
WP_106471446.1\|1243272_1244443_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	7.1e-48	38.5
WP_106471650.1\|1245085_1245985_-	EamA family transporter	NA	NA	NA	NA
WP_106471651.1\|1246068_1246551_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_106471652.1\|1248757_1252408_+	glycosyltransferase	NA	NA	NA	NA
WP_149615467.1\|1252747_1253092_-	hypothetical protein	NA	NA	NA	NA
WP_106471654.1\|1253314_1253506_+	DUF4169 family protein	NA	NA	NA	NA
WP_106471655.1\|1253502_1253718_+	ribbon-helix-helix domain-containing protein	NA	NA	NA	NA
WP_106471656.1\|1253763_1254912_+	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_106471657.1\|1255029_1258473_+	pyruvate carboxylase	NA	NA	NA	NA
WP_106471658.1\|1258825_1259065_-	Lrp/AsnC ligand binding domain-containing protein	NA	NA	NA	NA
WP_106471659.1\|1259232_1259820_+	imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_106471660.1\|1259874_1260513_+	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_149615468.1\|1260517_1260940_-	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_106471662.1\|1261043_1261430_-	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_106471663.1\|1261563_1262286_+	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_106471664.1\|1262288_1262738_-	DUF302 domain-containing protein	NA	NA	NA	NA
WP_106471665.1\|1262857_1263619_+	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_106471666.1\|1263630_1263945_+	phosphoribosyl-ATP diphosphatase	NA	NA	NA	NA
WP_106473978.1\|1263955_1264426_-	CoA-binding protein	NA	NA	NA	NA
WP_106473979.1\|1264629_1265046_-	YHS domain protein	NA	NA	NA	NA
WP_106471667.1\|1265232_1265565_-	hypothetical protein	NA	NA	NA	NA
WP_106471668.1\|1265661_1266432_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_106471669.1\|1266716_1267763_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_106471670.1\|1267759_1267978_-	hypothetical protein	NA	NA	NA	NA
WP_106471671.1\|1267987_1268344_-	hypothetical protein	A0A240F4W3	Ochrobactrum_phage	5.4e-23	48.6
WP_106471672.1\|1268340_1269273_-	DUF5131 family protein	Q8W6F1	Sinorhizobium_phage	2.2e-68	48.0
WP_106471673.1\|1269269_1270586_-	ParB N-terminal domain-containing protein	A0A0U2C144	Paracoccus_phage	3.4e-38	39.6
1270763:1270779	attR	NA	NA	NA	NA

DBSCAN-SWA_85

1274660 : 1304831

Escherichia_phage(20.0%)

tail,plate,terminase,capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471685.1\|1274660_1275287_+	helix-turn-helix domain-containing protein	A0A068CE61	Rhizobium_phage	2.1e-14	44.4
WP_106471686.1\|1275283_1275565_+	hypothetical protein	NA	NA	NA	NA
WP_106471687.1\|1275940_1276495_+	hypothetical protein	A0A1B0UYW1	Roseobacter_phage	1.8e-17	48.2
WP_106473980.1\|1276885_1277158_+	DUF2312 domain-containing protein	A0A1X9HX62	Ruegeria_phage	1.7e-32	85.6
WP_106471688.1\|1277161_1277551_+	DUF1064 domain-containing protein	A0A1X9HVJ6	Ruegeria_phage	3.4e-39	68.0
WP_106471689.1\|1277547_1278186_+	DNA methyltransferase	F8TVB4	EBPR_siphovirus	5.6e-63	54.7
WP_106471690.1\|1278175_1278616_+	hypothetical protein	V5YTF6	Pseudomonas_phage	8.4e-18	40.7
WP_106473981.1\|1278648_1279365_+	glycoside hydrolase family 108 protein	A0A1X9HX89	Ruegeria_phage	1.0e-57	52.8
WP_106471691.1\|1279366_1279591_+	hypothetical protein	NA	NA	NA	NA
WP_106471692.1\|1279590_1280016_+	hypothetical protein	A0A1X9HVL7	Ruegeria_phage	4.6e-29	51.1
WP_106471693.1\|1280138_1280678_+	DNA-packaging protein	A0A193GYK5	Enterobacter_phage	3.1e-30	46.6
WP_106471694.1\|1280674_1282645_+\|terminase	phage terminase large subunit family protein	A0A088FQV3	Escherichia_phage	3.2e-218	60.2
WP_149615472.1\|1282647_1283178_+	hypothetical protein	A0A1W6JT65	Escherichia_phage	9.8e-29	41.4
WP_106471696.1\|1283177_1284767_+\|portal	phage portal protein	A0A193GYC1	Enterobacter_phage	1.8e-139	51.7
WP_106471697.1\|1284771_1286763_+\|capsid	phage major capsid protein	D5LH01	Escherichia_phage	1.1e-181	52.9
WP_106471698.1\|1286823_1287036_+	hypothetical protein	NA	NA	NA	NA
WP_106471699.1\|1287039_1287375_+	hypothetical protein	R9TMM0	Vibrio_phage	3.6e-05	32.0
WP_149615473.1\|1287361_1287895_+\|tail	phage tail protein	D5LGZ7	Escherichia_phage	6.6e-33	43.4
WP_106471701.1\|1288289_1288817_+	hypothetical protein	NA	NA	NA	NA
WP_106471702.1\|1288871_1289210_+\|plate	phage baseplate protein	V5YTB2	Pseudomonas_phage	2.1e-32	60.4
WP_106471703.1\|1289206_1290109_+\|plate	baseplate assembly protein	D5LGZ3	Escherichia_phage	9.0e-75	52.5
WP_106473982.1\|1290110_1290671_+\|tail	phage tail protein I	U5N0U8	Enterobacteria_phage	3.6e-21	33.7
WP_106471704.1\|1290670_1291627_+	DUF2793 domain-containing protein	A0A0A1IV74	Pseudomonas_phage	2.9e-07	52.3
WP_106471705.1\|1291636_1292251_+	hypothetical protein	NA	NA	NA	NA
WP_106471706.1\|1292281_1292665_+	hypothetical protein	A0A1B1INQ1	uncultured_Mediterranean_phage	6.4e-14	37.2
WP_106471707.1\|1292667_1293156_+	hypothetical protein	NA	NA	NA	NA
WP_106471708.1\|1293157_1294771_+	hypothetical protein	NA	NA	NA	NA
WP_106471709.1\|1294773_1295094_+\|plate	BppU family phage baseplate upper protein	NA	NA	NA	NA
WP_149615474.1\|1295120_1296488_-	hypothetical protein	R9TRQ8	Vibrio_phage	4.9e-24	29.4
WP_106471711.1\|1296640_1297828_+\|tail	phage tail protein	V5YTI0	Pseudomonas_phage	1.4e-144	59.2
WP_106471712.1\|1297827_1298334_+\|tail	phage major tail tube protein	A0A088FRU2	Escherichia_phage	4.0e-48	55.4
WP_106471713.1\|1298346_1298631_+\|tail	phage tail assembly protein	V5YST8	Pseudomonas_phage	2.6e-12	39.8
WP_149615475.1\|1298543_1298762_+	hypothetical protein	NA	NA	NA	NA
WP_106471714.1\|1298751_1301070_+\|tail	phage tail tape measure protein	A0A088F717	Idiomarinaceae_phage	7.3e-20	28.5
WP_106471715.1\|1301072_1301486_+\|tail	phage tail protein	A0A193GYE0	Enterobacter_phage	4.3e-32	54.8
WP_106471716.1\|1301448_1301673_+\|tail	phage tail protein	U5N3E7	Enterobacteria_phage	1.4e-08	58.3
WP_106471717.1\|1301663_1302671_+	late control protein D	A0A1B2LRT8	Wolbachia_phage	1.5e-30	30.6
WP_106471718.1\|1302740_1303100_+	nuclease	A0A127AWE6	Bacillus_phage	7.1e-07	38.8
WP_149615476.1\|1303102_1303363_+	hypothetical protein	NA	NA	NA	NA
WP_106471720.1\|1303697_1304831_-	alkane 1-monooxygenase	A0A1V0SBK9	Catovirus	4.1e-40	31.9

DBSCAN-SWA_86

1316216 : 1317605

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471732.1\|1316216_1317605_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	3.4e-41	28.4

DBSCAN-SWA_87

1348663 : 1350403

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471762.1\|1348663_1350403_+	sulfate permease	A0A2H4J153	uncultured_Caudovirales_phage	6.1e-11	24.4

DBSCAN-SWA_88

1354809 : 1358094

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471767.1\|1354809_1355814_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.4e-12	32.4
WP_106471768.1\|1355810_1356584_+	L-iditol 2-dehydrogenase	NA	NA	NA	NA
WP_106471769.1\|1356612_1358094_+	mannitol dehydrogenase family protein	H8ZJP8	Ostreococcus_tauri_virus	1.3e-43	30.5

DBSCAN-SWA_89

1365125 : 1365923

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471775.1\|1365125_1365923_+	phosphonate ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.3e-13	25.9

DBSCAN-SWA_90

1381511 : 1382585

Tupanvirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471793.1\|1381511_1382585_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	2.6e-28	37.7

DBSCAN-SWA_91

1402443 : 1403675

Burkholderia_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106470855.1\|1402443_1403675_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	2.3e-81	57.3

DBSCAN-SWA_92

1408095 : 1410107

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471813.1\|1408095_1409115_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.7e-19	33.0
WP_106471814.1\|1409111_1410107_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	4.0e-07	30.9

DBSCAN-SWA_93

1419422 : 1423607

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473992.1\|1419422_1420181_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.7e-31	40.6
WP_106473993.1\|1420215_1421316_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_106473994.1\|1421320_1422493_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_106471819.1\|1422593_1423607_-	amino acid ABC transporter substrate-binding protein	A0A1B1IT51	uncultured_Mediterranean_phage	1.2e-62	39.1

DBSCAN-SWA_94

1432998 : 1434609

Organic_Lake_phycodnavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471829.1\|1432998_1434609_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.2e-10	27.9

DBSCAN-SWA_95

1439397 : 1441020

Catovirus(100.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473997.1\|1439397_1441020_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	5.8e-56	29.9

DBSCAN-SWA_96

1448119 : 1449631

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473998.1\|1448119_1449631_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.3e-19	32.4

DBSCAN-SWA_97

1460053 : 1460764

Sinorhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471851.1\|1460053_1460764_+	RNA polymerase sigma factor	A0A0F6TH34	Sinorhizobium_phage	1.2e-10	31.0

DBSCAN-SWA_98

1468193 : 1472709

Cedratvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474000.1\|1468193_1469219_+	ABC transporter ATP-binding protein	A0A2R8FFL6	Cedratvirus	4.4e-09	26.4
WP_106471859.1\|1469215_1470214_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.0e-18	32.1
WP_106471861.1\|1470213_1470867_+	flavin reductase family protein	NA	NA	NA	NA
WP_106471862.1\|1471561_1472239_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_106471863.1\|1472235_1472709_+	nucleoside deaminase	S4VYT2	Pandoravirus	1.2e-09	40.8

DBSCAN-SWA_99

1475878 : 1477336

Feldmannia_species_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474001.1\|1475878_1477336_-	two-component sensor histidine kinase	B5LWA6	Feldmannia_species_virus	9.3e-05	30.0

DBSCAN-SWA_100

1485523 : 1485751

Acidithiobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471874.1\|1485523_1485751_-	hypothetical protein	K4I1E3	Acidithiobacillus_phage	4.3e-18	65.3

DBSCAN-SWA_101

1498565 : 1503555

Rhizobium_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471885.1\|1498565_1499036_+	recombinase family protein	R9TP69	Rhizobium_phage	1.1e-28	43.0
WP_106471886.1\|1499051_1499999_+	hypothetical protein	R9TP69	Rhizobium_phage	8.6e-36	33.8
WP_149615493.1\|1499995_1500940_+	DUF2968 domain-containing protein	NA	NA	NA	NA
WP_106471887.1\|1501273_1501753_+	hypothetical protein	NA	NA	NA	NA
WP_149615494.1\|1501767_1502304_+	hypothetical protein	NA	NA	NA	NA
WP_106471888.1\|1502340_1503555_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.2e-37	42.3

DBSCAN-SWA_102

1511363 : 1512992

Rhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474003.1\|1511363_1512992_+	recombinase family protein	R9TP69	Rhizobium_phage	5.8e-80	36.6

DBSCAN-SWA_103

1520220 : 1521659

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471902.1\|1520220_1520949_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.9e-13	25.3
WP_106471903.1\|1520948_1521659_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.2e-19	27.1

DBSCAN-SWA_104

1528922 : 1536678

Thermoanaerobacterium_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471910.1\|1528922_1529489_+	helix-turn-helix transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	4.7e-05	40.6
WP_106471911.1\|1529578_1530766_+	glycine C-acetyltransferase	V5LQ39	Emiliania_huxleyi_virus	9.8e-29	30.0
WP_106474004.1\|1530777_1531806_+	L-threonine 3-dehydrogenase	R9TPW0	Vibrio_phage	5.9e-14	64.7
WP_106471912.1\|1531862_1532819_+	cysteine synthase family protein	NA	NA	NA	NA
WP_106471913.1\|1532825_1534115_-	nicotinate phosphoribosyltransferase	A0A2L0UZQ6	Agrobacterium_phage	9.4e-126	52.9
WP_106471914.1\|1534179_1536012_-	response regulator	A0A1V0SGX0	Hokovirus	8.0e-46	33.2
WP_106471915.1\|1536084_1536678_-	bifunctional nicotinamidase/pyrazinamidase	A0A1V0SEH9	Indivirus	3.0e-10	27.1

DBSCAN-SWA_105

1541014 : 1544790

Halomonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471920.1\|1541014_1541650_-	ParA family protein	B0ZSI1	Halomonas_phage	4.9e-19	34.4
WP_106471921.1\|1541780_1542479_+	hypothetical protein	NA	NA	NA	NA
WP_106471922.1\|1542501_1544790_-	hypothetical protein	X2KUH8	Vibrio_phage	1.7e-05	48.2

DBSCAN-SWA_106

1551393 : 1557330

Tupanvirus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471929.1\|1551393_1553049_+	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	7.5e-43	27.5
WP_106471930.1\|1553841_1554390_-\|transposase	transposase	NA	NA	NA	NA
WP_106471931.1\|1554510_1554825_+	divalent-cation tolerance protein CutA	NA	NA	NA	NA
WP_106471932.1\|1555005_1555212_+	cold-shock protein	Q9AZD3	Lactococcus_phage	7.1e-12	54.0
WP_106471933.1\|1555403_1555961_+	L,D-transpeptidase	NA	NA	NA	NA
WP_106471934.1\|1555970_1556624_-	arylesterase	NA	NA	NA	NA
WP_106471935.1\|1556616_1557330_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.2e-31	38.7

DBSCAN-SWA_107

1561058 : 1565583

Escherichia_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471939.1\|1561058_1562384_-\|tRNA	glutamate--tRNA ligase	A0A222YZ70	Escherichia_phage	3.1e-15	36.7
WP_106471940.1\|1562449_1562878_-	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_106471941.1\|1562988_1563912_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_106471942.1\|1563924_1565583_-	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	1.2e-101	40.6

DBSCAN-SWA_108

1579229 : 1580932

Caulobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471953.1\|1579229_1579685_-	dUTP diphosphatase	K4JSC8	Caulobacter_phage	1.8e-31	52.2
WP_106471954.1\|1579735_1580932_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	7.6e-37	35.2

DBSCAN-SWA_109

1627094 : 1629284

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471992.1\|1627094_1629284_+	protein kinase	M1I1A9	Paramecium_bursaria_Chlorella_virus	1.5e-11	26.8

DBSCAN-SWA_110

1639497 : 1641663

Ralstonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472001.1\|1639497_1641663_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.5e-30	27.0

DBSCAN-SWA_111

1646436 : 1649142

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472004.1\|1646436_1649142_-	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	4.6e-82	29.3

DBSCAN-SWA_112

1681229 : 1684470

Tetraselmis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472037.1\|1681229_1682753_-	2-polyprenylphenol 6-hydroxylase	A0A2P0VMP1	Tetraselmis_virus	2.5e-16	24.9
WP_106472038.1\|1682756_1683521_-	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_106472039.1\|1683618_1684470_+	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	G3MA33	Bacillus_virus	9.5e-26	31.6

DBSCAN-SWA_113

1687920 : 1693251

Rhizobium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472043.1\|1687920_1689039_+	DNA polymerase III subunit beta	B4UTW9	Rhizobium_phage	1.6e-68	43.5
WP_106472044.1\|1689035_1690139_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_106472045.1\|1690135_1690756_+	LysE family translocator	NA	NA	NA	NA
WP_106472046.1\|1690833_1693251_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.0e-109	34.0

DBSCAN-SWA_114

1709426 : 1711004

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472051.1\|1709426_1711004_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-21	32.6

DBSCAN-SWA_115

1728690 : 1734405

Brazilian_cedratvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472064.1\|1728690_1729509_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.4e-18	27.6
WP_106472065.1\|1729605_1731576_-	AMP-binding protein	A0A1V0SBX8	Catovirus	1.1e-27	21.2
WP_106472066.1\|1731799_1733707_+	PAS domain-containing protein	NA	NA	NA	NA
WP_106472067.1\|1733703_1734405_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.5e-21	31.4

DBSCAN-SWA_116

1740309 : 1744990

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472072.1\|1740309_1741365_+	saccharopine dehydrogenase	A0A2K9L078	Tupanvirus	1.3e-61	36.1
WP_106472073.1\|1741466_1741784_-	DUF3775 domain-containing protein	NA	NA	NA	NA
WP_106472074.1\|1741892_1743131_-	DNA recombination protein RmuC	NA	NA	NA	NA
WP_106472075.1\|1743127_1744990_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	4.7e-110	41.2

DBSCAN-SWA_117

1749850 : 1753966

Megavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472078.1\|1749850_1751203_-	insulinase family protein	A0A2P1EIE5	Megavirus	8.0e-19	29.6
WP_106472079.1\|1751317_1751836_-	DUF3035 domain-containing protein	NA	NA	NA	NA
WP_106472080.1\|1751865_1752372_-	signal peptidase II	NA	NA	NA	NA
WP_106472081.1\|1752376_1753966_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.4e-70	48.6

DBSCAN-SWA_118

1771005 : 1771863

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472099.1\|1771005_1771863_-	alpha-1,2-fucosyltransferase	A0A2H4UUT1	Bodo_saltans_virus	2.6e-23	34.2

DBSCAN-SWA_119

1777137 : 1778190

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472106.1\|1777137_1778190_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	2.1e-22	33.5

DBSCAN-SWA_120

1783525 : 1784638

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472111.1\|1783525_1784638_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	3.3e-26	29.0

DBSCAN-SWA_121

1799341 : 1807546

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472124.1\|1799341_1800121_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-14	28.4
WP_106472125.1\|1800189_1801041_+	phosphohydrolase	NA	NA	NA	NA
WP_106472126.1\|1801172_1801523_+	TIGR01841 family phasin	NA	NA	NA	NA
WP_106472127.1\|1801651_1802887_-	DUF445 domain-containing protein	NA	NA	NA	NA
WP_106472128.1\|1802920_1803730_-	poly(3-hydroxyalkanoate) depolymerase	A0A1L7N183	Ralstonia_phage	6.8e-66	50.4
WP_106472129.1\|1803733_1805401_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_106472130.1\|1805422_1805890_-	MaoC family dehydratase	NA	NA	NA	NA
WP_106472131.1\|1805911_1807546_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	4.5e-32	25.0

DBSCAN-SWA_122

1816817 : 1817282

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472141.1\|1816817_1817282_-	Hsp20 family protein	E3SKK3	Synechococcus_phage	5.2e-18	36.2

DBSCAN-SWA_123

1832852 : 1833539

Bradyrhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472158.1\|1832852_1833539_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	8.4e-57	51.1

DBSCAN-SWA_124

1841595 : 1843311

Natrialba_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472164.1\|1841595_1842405_+	ParA family protein	Q8JL10	Natrialba_phage	5.1e-21	30.7
WP_106472165.1\|1842426_1843311_+	ParB/RepB/Spo0J family partition protein	A0A1C9EHW0	Gordonia_phage	2.7e-15	34.3

DBSCAN-SWA_125

1847607 : 1850256

Cafeteria_roenbergensis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472171.1\|1847607_1850256_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	3.5e-18	20.2

DBSCAN-SWA_126

1856467 : 1864237

Feldmannia_species_virus(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472177.1\|1856467_1857763_+	fused response regulator/phosphatase	B5LWA6	Feldmannia_species_virus	5.7e-06	27.0
WP_106472178.1\|1857767_1858229_-	NUDIX hydrolase	NA	NA	NA	NA
WP_106472179.1\|1858304_1859246_+	molecular chaperone Hsp33	NA	NA	NA	NA
WP_106472180.1\|1859238_1859835_+	CoA pyrophosphatase	NA	NA	NA	NA
WP_106472181.1\|1859831_1860983_+\|tRNA	CCA tRNA nucleotidyltransferase	A0A1B0V011	Roseobacter_phage	2.6e-50	43.5
WP_106472182.1\|1861154_1863002_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.2e-30	27.1
WP_106472183.1\|1862998_1864237_+	class I SAM-dependent RNA methyltransferase	A0A2K5B251	Erysipelothrix_phage	1.6e-10	36.8

DBSCAN-SWA_127

1870076 : 1870337

Rhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472191.1\|1870076_1870337_+	glutaredoxin 3	V9QKN6	Rhizobium_phage	3.1e-12	46.1

DBSCAN-SWA_128

1877216 : 1879715

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472200.1\|1877216_1879715_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.6e-18	23.4

DBSCAN-SWA_129

1887383 : 1890835

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472205.1\|1887383_1887998_+	ribonuclease D	K7XYU9	uncultured_Mediterranean_phage	1.3e-11	32.8
WP_106472206.1\|1887994_1888954_+	KpsF/GutQ family sugar-phosphate isomerase	NA	NA	NA	NA
WP_106472207.1\|1888963_1889563_+	hypothetical protein	NA	NA	NA	NA
WP_106472208.1\|1889567_1890077_+	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_106472209.1\|1890076_1890835_+	LPS export ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	2.7e-16	28.0

DBSCAN-SWA_130

1897581 : 1899455

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472215.1\|1897581_1898565_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	7.3e-46	33.2
WP_106472216.1\|1898561_1899455_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.4e-64	47.4

DBSCAN-SWA_131

1903954 : 1907908

Chrysanthemum_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472222.1\|1903954_1904557_-	alpha-ketoglutarate-dependent dioxygenase AlkB	A0A2P1JHW7	Chrysanthemum_virus	2.9e-05	28.8
WP_106472223.1\|1904774_1906682_+	molecular chaperone DnaK	A0A2P1ELQ7	Moumouvirus	7.6e-156	50.3
WP_106472224.1\|1906756_1907908_+	molecular chaperone DnaJ	A0A0P0YNN4	Yellowstone_lake_phycodnavirus	2.0e-18	31.2

DBSCAN-SWA_132

1911276 : 1912116

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472229.1\|1911276_1912116_-	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	5.3e-05	24.7

DBSCAN-SWA_133

1916648 : 1920980

Micromonas_sp._RCC1109_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472235.1\|1916648_1918238_-	5-guanidino-2-oxopentanoate decarboxylase	E5EQ70	Micromonas_sp._RCC1109_virus	8.5e-20	25.0
WP_106472236.1\|1918234_1919422_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_106472237.1\|1919418_1920060_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_106474031.1\|1920275_1920980_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.3e-09	31.4

DBSCAN-SWA_134

1925615 : 1928724

Bacillus_phage(50.0%)

integrase

attL 1917226:1917242|attR 1933068:1933084

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1917226:1917242	attL	NA	NA	NA	NA
WP_106472244.1\|1925615_1926374_-	HNH endonuclease	A0A0A0RV62	Bacillus_phage	3.8e-10	43.7
WP_106472245.1\|1926515_1926734_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_149615505.1\|1927009_1927519_-	hypothetical protein	NA	NA	NA	NA
WP_106472247.1\|1927515_1928724_-\|integrase	site-specific integrase	A0A1B0VMI6	Pseudomonas_phage	2.6e-16	25.5
1933068:1933084	attR	NA	NA	NA	NA

DBSCAN-SWA_135

1939147 : 1940428

Mamastrovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472258.1\|1939147_1940428_-	5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH	A9ZMK9	Mamastrovirus	2.2e-18	34.5

DBSCAN-SWA_136

1946441 : 1946567

Leptospira_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474033.1\|1946441_1946567_+\|transposase	transposase	S5WIN0	Leptospira_phage	4.9e-08	56.1

DBSCAN-SWA_137

1952580 : 1953537

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472268.1\|1952580_1953537_-	alpha/beta hydrolase	A0A0G2Y6Q1	Acanthamoeba_polyphaga_mimivirus	1.4e-25	28.5

DBSCAN-SWA_138

1959740 : 1961504

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472275.1\|1959740_1961504_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-22	32.3

DBSCAN-SWA_139

1966240 : 1970151

Bacillus_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472278.1\|1966240_1966990_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	3.5e-24	32.5
WP_106474035.1\|1966986_1967814_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_106472279.1\|1967859_1968849_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_106472280.1\|1969530_1970151_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.5e-36	46.8

DBSCAN-SWA_140

1976533 : 1978431

Anomala_cuprea_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472286.1\|1976533_1977475_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.9e-09	24.8
WP_106472287.1\|1977471_1978431_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.0e-16	27.1

DBSCAN-SWA_141

1982422 : 1989747

Hepacivirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472291.1\|1982422_1983970_-	long-chain-fatty-acid--CoA ligase	Q75ZG1	Hepacivirus	4.0e-38	25.9
WP_106474036.1\|1983969_1985124_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_106472292.1\|1985179_1986343_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_106472293.1\|1986386_1988228_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	1.5e-63	27.5
WP_106472294.1\|1988218_1988980_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.8e-15	29.7
WP_106472295.1\|1988976_1989747_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.9e-12	26.6

DBSCAN-SWA_142

2001749 : 2003450

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472306.1\|2001749_2003450_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	4.1e-28	35.2

DBSCAN-SWA_143

2013342 : 2014380

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474039.1\|2013342_2014380_+	phosphate ABC transporter substrate-binding protein	A0A1B1IWY0	uncultured_Mediterranean_phage	1.9e-89	49.8

DBSCAN-SWA_144

2018696 : 2025237

Bacillus_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472315.1\|2018696_2019386_+	phosphate regulon transcriptional regulatory protein PhoB	W8CYM9	Bacillus_phage	2.5e-40	37.2
WP_106472316.1\|2019396_2020290_-	oxygen-dependent coproporphyrinogen oxidase	NA	NA	NA	NA
WP_106472317.1\|2020326_2021133_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_106472318.1\|2021168_2022149_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_106472319.1\|2022160_2022505_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	1.2e-11	39.6
WP_106472320.1\|2022600_2023296_+	HAD family hydrolase	NA	NA	NA	NA
WP_106472321.1\|2023551_2025237_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	7.4e-30	36.0

DBSCAN-SWA_145

2029367 : 2035067

Sinorhizobium_phage(50.0%)

integrase

attL 2029347:2029365|attR 2045111:2045129

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2029347:2029365	attL	NA	NA	NA	NA
WP_106472325.1\|2029367_2030486_-\|integrase	tyrosine-type recombinase/integrase	A0A291AUF0	Sinorhizobium_phage	1.2e-44	35.6
WP_106472326.1\|2030672_2030912_-	hypothetical protein	NA	NA	NA	NA
WP_106472327.1\|2031050_2031473_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149615510.1\|2031448_2031808_+	hypothetical protein	NA	NA	NA	NA
WP_106472329.1\|2031863_2035067_+	site-specific DNA-methyltransferase	G8I4P9	Mycobacterium_phage	1.8e-21	25.3
2045111:2045129	attR	NA	NA	NA	NA

DBSCAN-SWA_146

2048107 : 2054343

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472336.1\|2048107_2048869_-	hypothetical protein	A0A2K9L4V2	Tupanvirus	1.4e-12	34.8
WP_106472337.1\|2049466_2050933_+	DNA polymerase Y family protein	NA	NA	NA	NA
WP_106472338.1\|2050929_2054343_+	DNA polymerase III subunit alpha	A0A096XUX6	Cronobacter_phage	4.8e-60	31.8

DBSCAN-SWA_147

2060257 : 2066023

Pelagibacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007818122.1\|2060257_2060464_+	30S ribosomal protein S21	M1HLV7	Pelagibacter_phage	1.3e-05	63.2
WP_106472346.1\|2060686_2061541_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_106472347.1\|2061584_2063171_-	NAD(P)-binding protein	A0A1V0S9M4	Catovirus	8.5e-44	28.4
WP_106472348.1\|2063237_2063696_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_106472349.1\|2063835_2064954_+	alanine dehydrogenase	NA	NA	NA	NA
WP_106472350.1\|2065000_2066023_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	Q6GZ03	Mycoplasma_phage	1.1e-15	43.8

DBSCAN-SWA_148

2074338 : 2074662

Roseobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472358.1\|2074338_2074662_-	hypothetical protein	F4YXP2	Roseobacter_phage	4.4e-16	55.0

DBSCAN-SWA_149

2087883 : 2091290

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472374.1\|2087883_2090007_+	elongation factor G	A0A2K9L6L3	Tupanvirus	5.5e-38	23.3
WP_106472375.1\|2090114_2091290_+	elongation factor Tu	A0A146JG10	Tokyovirus	1.3e-17	29.1

DBSCAN-SWA_150

2106314 : 2112429

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472400.1\|2106314_2106974_+	adenylate kinase	A0A2K9L833	Tupanvirus	1.4e-05	34.5
WP_106472401.1\|2107159_2107528_+	30S ribosomal protein S13	NA	NA	NA	NA
WP_106472402.1\|2107540_2107933_+	30S ribosomal protein S11	NA	NA	NA	NA
WP_106474045.1\|2108048_2109065_+	DNA-directed RNA polymerase subunit alpha	NA	NA	NA	NA
WP_106472403.1\|2109184_2109604_+	50S ribosomal protein L17	NA	NA	NA	NA
WP_106472404.1\|2109730_2111113_+	PDZ domain-containing protein	A0A1B1IRD3	uncultured_Mediterranean_phage	3.3e-12	32.6
WP_106472405.1\|2111118_2112429_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	7.2e-73	39.2

DBSCAN-SWA_151

2115500 : 2123592

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472410.1\|2115500_2116520_+	amino acid ABC transporter substrate-binding protein	A0A1B1IT51	uncultured_Mediterranean_phage	1.3e-74	44.0
WP_106472411.1\|2116646_2117915_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_106472412.1\|2117916_2119224_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_106472413.1\|2119236_2120028_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.4e-31	40.4
WP_106472414.1\|2120141_2120639_-	phosphoglycerate mutase	NA	NA	NA	NA
WP_106472415.1\|2120623_2121319_-	ferredoxin	NA	NA	NA	NA
WP_106472416.1\|2121331_2122066_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_106472417.1\|2122062_2123592_-	AAA family ATPase	B2ZYA4	Ralstonia_phage	5.0e-09	24.6

DBSCAN-SWA_152

2144380 : 2152848

Chrysochromulina_ericina_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474047.1\|2144380_2148517_+	DNA-directed RNA polymerase subunit beta	A0A0N9R0J7	Chrysochromulina_ericina_virus	5.8e-28	28.9
WP_106472438.1\|2148609_2152848_+	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	5.5e-66	27.3

DBSCAN-SWA_153

2166764 : 2168570

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472447.1\|2166764_2168570_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	5.9e-09	28.4

DBSCAN-SWA_154

2176527 : 2177754

Oenococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472453.1\|2176527_2177754_-	mandelate racemase/muconate lactonizing enzyme family protein	Q6A202	Oenococcus_phage	5.5e-43	33.2

DBSCAN-SWA_155

2196679 : 2197861

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472470.1\|2196679_2197861_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.0e-94	49.1

DBSCAN-SWA_156

2231862 : 2238852

Vibrio_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472505.1\|2231862_2233503_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	4.0e-20	24.3
WP_106472506.1\|2233599_2234832_+	aminotransferase class V-fold PLP-dependent enzyme	Q2XUY6	environmental_halophage	1.2e-24	24.3
WP_106472507.1\|2234922_2236134_+	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	1.3e-41	31.3
WP_106472508.1\|2236154_2236595_+	TrgA family protein	NA	NA	NA	NA
WP_106472509.1\|2236623_2237751_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_106472510.1\|2237817_2238852_+	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	9.4e-44	37.0

DBSCAN-SWA_157

2242971 : 2244297

Acidithiobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472514.1\|2242971_2244297_-	recombinase family protein	K4ICM1	Acidithiobacillus_phage	1.8e-116	50.7

DBSCAN-SWA_158

2247956 : 2254465

Enterobacteria_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106471446.1\|2247956_2249127_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	7.1e-48	38.5
WP_149615516.1\|2250280_2250934_-	hypothetical protein	NA	NA	NA	NA
WP_106472519.1\|2250955_2254465_-	DUF3883 domain-containing protein	A0A1B1IUI1	uncultured_Mediterranean_phage	3.1e-54	29.6

DBSCAN-SWA_159

2263877 : 2268061

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472526.1\|2263877_2264912_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	4.3e-20	48.4
WP_106472527.1\|2265229_2266486_+	aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_106472528.1\|2266478_2267195_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_106472529.1\|2267212_2268061_+	transketolase	A0A0P0YMZ3	Yellowstone_lake_phycodnavirus	9.2e-13	31.7

DBSCAN-SWA_160

2277570 : 2282564

Burkholderia_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472537.1\|2277570_2278801_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.0e-81	57.3
WP_106474059.1\|2279019_2279964_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_106472538.1\|2279891_2280908_+	transporter	NA	NA	NA	NA
WP_106472539.1\|2280971_2282564_+	arylsulfatase	A0A2P0VMN7	Tetraselmis_virus	1.5e-133	47.3

DBSCAN-SWA_161

2290945 : 2291665

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472546.1\|2290945_2291665_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.2e-16	31.1

DBSCAN-SWA_162

2296998 : 2299224

Ectocarpus_siliculosus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472551.1\|2296998_2299224_+	response regulator	Q8QNA2	Ectocarpus_siliculosus_virus	3.0e-10	30.7

DBSCAN-SWA_163

2313506 : 2316233

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472561.1\|2313506_2316233_+	ribosome-associated ATPase/putative transporter RbbA	W6JKT0	Anomala_cuprea_entomopoxvirus	2.7e-13	27.6

DBSCAN-SWA_164

2340013 : 2344088

Organic_Lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615560.1\|2340013_2341006_+	ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	1.1e-09	27.2
WP_106472579.1\|2341055_2342531_+	leucyl aminopeptidase	NA	NA	NA	NA
WP_106474066.1\|2342672_2343155_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_106472580.1\|2343335_2344088_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-11	29.1

DBSCAN-SWA_165

2348675 : 2349698

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472585.1\|2348675_2349698_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	4.1e-15	31.6

DBSCAN-SWA_166

2360330 : 2362288

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472595.1\|2360330_2361311_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.6e-14	28.1
WP_106472596.1\|2361307_2362288_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.8e-10	23.7

DBSCAN-SWA_167

2368332 : 2369073

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472598.1\|2368332_2369073_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	3.2e-09	34.7

DBSCAN-SWA_168

2375627 : 2380163

Pandoravirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472606.1\|2375627_2376731_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-68	41.6
WP_106474071.1\|2376962_2377940_+	thiamine ABC transporter substrate binding subunit	NA	NA	NA	NA
WP_106472607.1\|2377915_2379472_+	thiamine/thiamine pyrophosphate ABC transporter permease ThiP	NA	NA	NA	NA
WP_106472608.1\|2379458_2380163_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.9e-18	34.0

DBSCAN-SWA_169

2384057 : 2386250

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472612.1\|2384057_2386250_-	cadmium-translocating P-type ATPase	A0A218MNH6	uncultured_virus	5.6e-54	27.6

DBSCAN-SWA_170

2397263 : 2399810

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472623.1\|2397263_2399810_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	2.2e-155	36.6

DBSCAN-SWA_171

2403172 : 2404273

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472626.1\|2403172_2404273_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.4e-34	48.6

DBSCAN-SWA_172

2409260 : 2410793

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472632.1\|2409260_2410793_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.7e-18	29.4

DBSCAN-SWA_173

2416931 : 2417846

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472640.1\|2416931_2417846_+	co-chaperone YbbN	A0A1X9I9P5	Staphylococcus_phage	1.2e-10	34.6

DBSCAN-SWA_174

2425643 : 2426510

Escherichia_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472648.1\|2425643_2426510_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	1.5e-74	54.6

DBSCAN-SWA_175

2433159 : 2435760

Pithovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472653.1\|2433159_2434101_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	5.2e-17	29.2
WP_106472654.1\|2434097_2434859_+	ABC transporter permease	NA	NA	NA	NA
WP_106472655.1\|2434962_2435760_+	S49 family peptidase	A0A2I7QTH6	Vibrio_phage	2.1e-11	29.9

DBSCAN-SWA_176

2457756 : 2459738

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472677.1\|2457756_2458722_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.4e-11	26.1
WP_106472678.1\|2458718_2459738_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.5e-14	30.6

DBSCAN-SWA_177

2466654 : 2467428

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474085.1\|2466654_2467428_+	uracil-DNA glycosylase	A0A127AW33	Bacillus_phage	2.7e-11	31.2

DBSCAN-SWA_178

2474144 : 2480546

Ralstonia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472689.1\|2474144_2474588_-	NUDIX hydrolase	A0A1L7N1W6	Ralstonia_phage	1.4e-07	34.5
WP_106472690.1\|2474584_2475406_-	hypothetical protein	NA	NA	NA	NA
WP_106474086.1\|2475561_2476116_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_106474087.1\|2476198_2477158_-	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	9.3e-38	38.2
WP_106472691.1\|2477301_2479020_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_106474088.1\|2479140_2480079_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_106472692.1\|2480081_2480546_+	hypothetical protein	A0A1L5C299	Pseudoalteromonas_phage	1.5e-09	37.1

DBSCAN-SWA_179

2491070 : 2491532

Salmonella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472705.1\|2491070_2491532_-	ribonuclease HI	J9Q745	Salmonella_phage	3.8e-37	55.5

DBSCAN-SWA_180

2496048 : 2498220

Bordetella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472713.1\|2496048_2498220_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A291L9W9	Bordetella_phage	7.6e-11	36.7

DBSCAN-SWA_181

2501735 : 2503774

Dishui_lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472719.1\|2501735_2502434_+	ribonuclease III	A0A2K9R4Y7	Dishui_lake_phycodnavirus	3.6e-15	35.0
WP_106474091.1\|2502457_2503774_-	serine hydroxymethyltransferase	A0A240F2Y9	Aeromonas_phage	1.3e-29	31.7

DBSCAN-SWA_182

2511659 : 2515790

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472726.1\|2511659_2513258_-	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	7.8e-138	48.8
WP_106472727.1\|2513480_2514176_+	response regulator transcription factor	NA	NA	NA	NA
WP_106472728.1\|2514191_2515790_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.6e-10	25.9

DBSCAN-SWA_183

2525511 : 2529834

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472739.1\|2525511_2527863_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.3e-88	40.0
WP_106472740.1\|2527930_2528518_+	hypothetical protein	NA	NA	NA	NA
WP_106472375.1\|2528658_2529834_+	elongation factor Tu	A0A146JG10	Tokyovirus	1.3e-17	29.1

DBSCAN-SWA_184

2536664 : 2537468

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472747.1\|2536664_2537468_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.9e-25	35.8

DBSCAN-SWA_185

2542485 : 2548549

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472752.1\|2542485_2545116_+	histidine kinase	W8CYF6	Bacillus_phage	3.0e-09	23.1
WP_106472753.1\|2545112_2546258_+	response regulator	NA	NA	NA	NA
WP_106472754.1\|2546219_2546978_-	response regulator transcription factor	W8CYM9	Bacillus_phage	5.9e-27	32.8
WP_106474098.1\|2547322_2548549_+	acetamidase/formamidase family protein	A0A1V0S8X7	Catovirus	2.6e-125	56.2

DBSCAN-SWA_186

2556013 : 2556955

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472761.1\|2556013_2556955_-	D-glycerate dehydrogenase	M1HUT5	Acanthocystis_turfacea_Chlorella_virus	2.6e-16	27.2

DBSCAN-SWA_187

2581761 : 2583757

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472779.1\|2581761_2582049_+	co-chaperone GroES	A0A221S4G8	uncultured_virus	1.1e-18	54.9
WP_106472780.1\|2582110_2583757_+	chaperonin GroEL	A0A240F779	uncultured_virus	3.1e-174	60.6

DBSCAN-SWA_188

2588412 : 2594869

Tetraselmis_virus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472786.1\|2588412_2588901_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.4e-19	42.1
WP_106472787.1\|2588982_2589207_-	YdcH family protein	NA	NA	NA	NA
WP_106474102.1\|2589372_2589786_+	Hsp20 family protein	H8ZNE8	Synechococcus_phage	3.9e-17	39.8
WP_106472788.1\|2589789_2590014_+	DUF1150 family protein	NA	NA	NA	NA
WP_106472789.1\|2590010_2590892_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_106472790.1\|2590884_2591748_+	hypothetical protein	A0A1V0SAK9	Catovirus	1.2e-12	26.8
WP_106472791.1\|2592056_2593769_-	bifunctional sulfate adenylyltransferase/adenylylsulfate kinase	A0A2K9L0F0	Tupanvirus	4.6e-120	42.1
WP_106472792.1\|2593924_2594869_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	8.8e-65	43.4

DBSCAN-SWA_189

2600310 : 2600715

Sinorhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472798.1\|2600310_2600715_-	helix-turn-helix transcriptional regulator	Q8W6G2	Sinorhizobium_phage	1.4e-14	40.6

DBSCAN-SWA_190

2610317 : 2610551

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472808.1\|2610317_2610551_+	acyl carrier protein	A0A2I7RIC8	Vibrio_phage	1.5e-05	41.8

DBSCAN-SWA_191

2615225 : 2634006

Paracoccus_phage(25.0%)

head,tail,protease,capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472814.1\|2615225_2616452_+	DNA-packaging protein	A0A1V0DY66	Dinoroseobacter_phage	6.7e-73	41.8
WP_106472815.1\|2616587_2617775_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	1.0e-57	36.9
WP_106472816.1\|2617767_2618004_+	hypothetical protein	NA	NA	NA	NA
WP_106472817.1\|2618038_2618596_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	2.4e-33	48.3
WP_106472818.1\|2618641_2619820_+\|capsid	phage major capsid protein	A0A2D1GNH4	Pseudomonas_phage	6.7e-70	39.0
WP_106472819.1\|2619992_2620592_+	hypothetical protein	NA	NA	NA	NA
WP_106472820.1\|2620588_2620927_+\|head	phage head closure protein	NA	NA	NA	NA
WP_106472821.1\|2620923_2621337_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_106472822.1\|2621360_2621774_+\|tail	phage major tail protein, TP901-1 family	A0A1J0GVL1	Pseudoalteromonas_phage	4.5e-05	31.9
WP_106472823.1\|2621777_2622098_+	gene transfer agent family protein	NA	NA	NA	NA
WP_106472824.1\|2622094_2622298_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_106472825.1\|2622290_2622953_+\|tail	phage tail tape measure protein	A0A1B2AQ26	Escherichia_phage	9.7e-10	32.1
WP_106472826.1\|2622974_2623607_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	8.5e-56	49.8
WP_106472827.1\|2623606_2624494_+	DUF2163 domain-containing protein	A0A0K0PVK1	Roseobacter_phage	5.8e-58	41.0
WP_106472828.1\|2624490_2624940_+	peptidase	A0A1V0DYB6	Dinoroseobacter_phage	1.3e-26	45.0
WP_106472829.1\|2624939_2628869_+	host specificity protein	A0A0B5A7K5	Paracoccus_phage	9.3e-217	38.3
WP_106472830.1\|2628868_2629165_+	hypothetical protein	NA	NA	NA	NA
WP_106472831.1\|2629227_2629749_+	winged helix DNA-binding protein	NA	NA	NA	NA
WP_106472832.1\|2629833_2631441_+	peptide chain release factor 3	D0R0F5	Streptococcus_phage	1.3e-31	28.4
WP_106474103.1\|2631368_2632385_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_106472833.1\|2632478_2633375_+	DMT family transporter	NA	NA	NA	NA
WP_106472834.1\|2633457_2634006_-	peroxiredoxin	M1I839	Pelagibacter_phage	4.5e-45	52.7

DBSCAN-SWA_192

2647870 : 2651413

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472847.1\|2647870_2648941_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	7.8e-17	43.6
WP_106472848.1\|2648937_2649792_+	ABC transporter permease	NA	NA	NA	NA
WP_106472849.1\|2649791_2650604_+	ABC transporter permease	NA	NA	NA	NA
WP_106472850.1\|2650642_2651413_+	3-oxoacyl-ACP reductase FabG	A0A0N9R355	Chrysochromulina_ericina_virus	1.7e-10	25.3

DBSCAN-SWA_193

2664774 : 2666121

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472869.1\|2664774_2666121_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	9.3e-84	41.3

DBSCAN-SWA_194

2669206 : 2670331

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472873.1\|2669206_2670331_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	9.3e-21	35.6

DBSCAN-SWA_195

2675169 : 2676270

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472877.1\|2675169_2676270_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	4.1e-21	29.0

DBSCAN-SWA_196

2682608 : 2684870

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472884.1\|2682608_2684870_-	ribonuclease R	Q0GXV6	Lactococcus_phage	3.2e-52	30.5

DBSCAN-SWA_197

2689650 : 2690493

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472890.1\|2689650_2690493_+	LOG family protein	A0A1D8KU27	Synechococcus_phage	2.7e-12	34.0

DBSCAN-SWA_198

2703309 : 2708889

Cedratvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472902.1\|2703309_2704905_+	phosphoglycerate dehydrogenase	A0A2R8FCS0	Cedratvirus	7.0e-46	39.3
WP_106472903.1\|2705099_2705828_+	serine/threonine protein phosphatase	A0A1V0EF12	Caulobacter_phage	3.1e-25	35.5
WP_106472904.1\|2705831_2707283_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_106472905.1\|2707275_2708889_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-21	36.9

DBSCAN-SWA_199

2739498 : 2740404

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472926.1\|2739498_2740404_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.9e-20	30.5

DBSCAN-SWA_200

2758302 : 2759112

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472945.1\|2758302_2759112_+	CbbQ/NirQ/NorQ/GpvN family protein	A0A2H4N7N3	Lake_Baikal_phage	2.1e-14	28.8

DBSCAN-SWA_201

2773398 : 2774463

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472956.1\|2773398_2774463_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.6e-25	37.5

DBSCAN-SWA_202

2787969 : 2790237

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472967.1\|2787969_2790237_+	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	2.7e-59	30.6

DBSCAN-SWA_203

2793518 : 2795327

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472972.1\|2793518_2795327_-	hypothetical protein	A0A2D2W2Q1	Stenotrophomonas_phage	3.7e-11	32.7

DBSCAN-SWA_204

2810553 : 2813294

uncultured_Mediterranean_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106472983.1\|2810553_2812014_+	DEAD/DEAH box helicase	A0A0N9Q9J4	Chrysochromulina_ericina_virus	1.9e-50	32.1
WP_106472984.1\|2812243_2812795_-	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	9.1e-38	55.2
WP_106472985.1\|2812787_2813294_-	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	3.3e-42	54.4

DBSCAN-SWA_205

2830765 : 2832202

environmental_Halophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473001.1\|2830765_2832202_+	purine permease	H9YQ34	environmental_Halophage	1.7e-06	35.3

DBSCAN-SWA_206

2836305 : 2840048

Erysipelothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473004.1\|2836305_2838051_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	7.6e-46	28.7
WP_106473005.1\|2838545_2840048_-	purine permease	Q9KX94	Enterobacteria_phage	8.3e-25	26.0

DBSCAN-SWA_207

2859914 : 2863392

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473021.1\|2859914_2860691_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.4e-21	34.2
WP_106473022.1\|2860692_2861754_+	membrane dipeptidase	NA	NA	NA	NA
WP_106473023.1\|2861838_2863392_-	AMP-binding protein	Q75ZG1	Hepacivirus	3.9e-25	26.0

DBSCAN-SWA_208

2872449 : 2883248

Stenotrophomonas_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473031.1\|2872449_2875044_+	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	2.3e-38	31.0
WP_106474121.1\|2875223_2875919_+	cell wall hydrolase	A0A1B0UXM4	Roseobacter_phage	6.8e-22	45.5
WP_106473032.1\|2876076_2877015_+	diguanylate cyclase	NA	NA	NA	NA
WP_106473033.1\|2877011_2878028_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	9.0e-23	30.5
WP_106473034.1\|2878020_2879367_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_106473035.1\|2879370_2880759_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_106473036.1\|2880896_2882393_-	phosphomannomutase/phosphoglucomutase	A0A127AWJ1	Bacillus_phage	6.4e-25	25.9
WP_106473037.1\|2882414_2883248_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.3e-48	42.1

DBSCAN-SWA_209

2890791 : 2898072

Klosneuvirus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473044.1\|2890791_2891967_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	6.8e-14	29.4
WP_106473045.1\|2892047_2892974_+	ornithine carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.6e-18	27.3
WP_106473046.1\|2893020_2894520_-	inorganic phosphate transporter	V5LQA0	Emiliania_huxleyi_virus	1.6e-15	30.1
WP_106473047.1\|2894849_2895599_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	3.9e-07	35.5
WP_106474124.1\|2895603_2898072_-	ATP-dependent helicase HrpB	A0A2H4UU36	Bodo_saltans_virus	2.2e-30	28.0

DBSCAN-SWA_210

2903075 : 2915084

Bacillus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474125.1\|2903075_2903777_-	NAD-dependent deacylase	S5M4R0	Bacillus_phage	2.3e-17	30.5
WP_106474126.1\|2903880_2904333_+	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_106473053.1\|2904329_2905295_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_106473054.1\|2905382_2905691_-	hypothetical protein	NA	NA	NA	NA
WP_106473055.1\|2906064_2907864_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	1.6e-22	25.1
WP_106473056.1\|2907939_2908698_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_106473057.1\|2908775_2909144_+	hypothetical protein	NA	NA	NA	NA
WP_106473058.1\|2909229_2910525_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.0e-100	52.2
WP_106473059.1\|2910703_2911465_+	NAD kinase	NA	NA	NA	NA
WP_106473060.1\|2911703_2913134_-	amidase	NA	NA	NA	NA
WP_106473061.1\|2913194_2915084_-	propionyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	1.7e-59	31.9

DBSCAN-SWA_211

2918159 : 2919479

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473064.1\|2918159_2919479_+	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	2.0e-62	38.9

DBSCAN-SWA_212

2923310 : 2924936

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473069.1\|2923310_2924936_-	AMP-binding protein	A0A1V0SBX8	Catovirus	3.0e-12	20.3

DBSCAN-SWA_213

2943782 : 2950485

Bacillus_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473083.1\|2943782_2947193_+	double-strand break repair helicase AddA	U5PSZ2	Bacillus_phage	2.6e-05	50.9
WP_106473084.1\|2947230_2947551_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	3.2e-19	50.0
WP_106473085.1\|2947604_2948525_-	hypothetical protein	NA	NA	NA	NA
WP_106473086.1\|2948623_2949181_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_106473087.1\|2949177_2950485_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A173GFL6	Erwinia_phage	6.1e-40	27.8

DBSCAN-SWA_214

2960837 : 2962312

Burkholderia_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473101.1\|2960837_2961401_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	3.3e-51	64.7
WP_106473102.1\|2961370_2962312_-\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	9.6e-11	20.4

DBSCAN-SWA_215

2982484 : 2983459

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473119.1\|2982484_2983459_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.3e-07	26.8

DBSCAN-SWA_216

2992813 : 2994522

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473130.1\|2992813_2993515_+	response regulator	W8CYM9	Bacillus_phage	8.3e-36	37.9
WP_106473131.1\|2993595_2994522_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	1.4e-43	34.0

DBSCAN-SWA_217

3011369 : 3013404

Prochlorococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473147.1\|3011369_3012341_-	GDP-L-fucose synthase	D1LW79	Prochlorococcus_phage	8.7e-84	51.2
WP_106473148.1\|3012330_3013404_-	GDP-mannose 4,6-dehydratase	M1IBC3	Acanthocystis_turfacea_Chlorella_virus	3.3e-124	61.5

DBSCAN-SWA_218

3033155 : 3037197

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473165.1\|3033155_3033632_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-28	46.1
WP_106473166.1\|3033713_3034571_+	3-mercaptopyruvate sulfurtransferase	NA	NA	NA	NA
WP_106473167.1\|3034570_3035755_+	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_106473168.1\|3035865_3037197_-	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	2.0e-54	37.1

DBSCAN-SWA_219

3041744 : 3048086

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473173.1\|3041744_3043469_+	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	1.6e-27	26.7
WP_106473174.1\|3043465_3044767_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_106473175.1\|3044838_3045300_+	RidA family protein	M1IDR7	Acanthocystis_turfacea_Chlorella_virus	1.4e-26	39.7
WP_106473176.1\|3045296_3046070_+	phosphodiesterase	NA	NA	NA	NA
WP_106473177.1\|3046100_3047288_+	N-acetyltransferase	NA	NA	NA	NA
WP_106473178.1\|3047284_3047581_+	4a-hydroxytetrahydrobiopterin dehydratase	NA	NA	NA	NA
WP_106473179.1\|3047597_3048086_-	peroxiredoxin	M1I839	Pelagibacter_phage	1.4e-18	40.8

DBSCAN-SWA_220

3064427 : 3069935

Microbacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473198.1\|3064427_3066587_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	9.2e-142	42.5
WP_106473199.1\|3066701_3067319_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_106473200.1\|3067315_3068305_-	adenosine kinase	NA	NA	NA	NA
WP_106473201.1\|3068301_3068946_-	endonuclease III	NA	NA	NA	NA
WP_106474135.1\|3069083_3069935_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	4.7e-17	50.6

DBSCAN-SWA_221

3075141 : 3079844

Pseudomonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473209.1\|3075141_3077124_-	lytic transglycosylase domain-containing protein	K4NWI2	Pseudomonas_phage	5.1e-22	43.3
WP_106473210.1\|3077244_3078117_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_106473211.1\|3078222_3079095_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_106473212.1\|3079094_3079844_-	4Fe-4S dicluster domain-containing protein	A0A077SL61	Escherichia_phage	1.3e-26	37.1

DBSCAN-SWA_222

3092513 : 3096744

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473223.1\|3092513_3093290_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.0e-34	43.6
WP_106473224.1\|3093286_3094555_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_106473225.1\|3094753_3095551_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_106473226.1\|3095658_3096744_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	3.3e-23	40.0

DBSCAN-SWA_223

3108974 : 3109937

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473235.1\|3108974_3109937_-	dipeptide ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.6e-16	29.7

DBSCAN-SWA_224

3130612 : 3131242

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473255.1\|3130612_3131242_-	queuosine precursor transporter	A0A1B1IR19	uncultured_Mediterranean_phage	1.8e-05	35.0

DBSCAN-SWA_225

3135002 : 3140663

Diadromus_pulchellus_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473260.1\|3135002_3137045_+	DNA helicase RecQ	F2NZ48	Diadromus_pulchellus_ascovirus	9.2e-75	40.7
WP_106473261.1\|3137073_3137868_+	peroxide stress protein YaaA	NA	NA	NA	NA
WP_106473262.1\|3137786_3138296_-	VOC family protein	NA	NA	NA	NA
WP_106473263.1\|3138323_3140663_-	response regulator	A0A1V0SGX0	Hokovirus	2.2e-48	33.3

DBSCAN-SWA_226

3166658 : 3167420

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473284.1\|3166658_3167420_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.5e-19	30.4

DBSCAN-SWA_227

3180046 : 3182896

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473294.1\|3180046_3182896_+	aminomethyl-transferring glycine dehydrogenase	E3SN07	Prochlorococcus_phage	5.6e-264	50.7

DBSCAN-SWA_228

3190376 : 3197130

Klosneuvirus(25.0%)

tRNA,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473301.1\|3190376_3193325_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SK04	Klosneuvirus	3.8e-21	30.1
WP_106473302.1\|3193375_3193831_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	4.9e-13	48.3
WP_106473303.1\|3193964_3194663_-\|holin	phosphatidylcholine synthase	NA	NA	NA	NA
WP_106473304.1\|3194702_3195632_-	tyrosine recombinase XerC	A0A166YH27	Gordonia_phage	5.7e-16	29.2
WP_106473305.1\|3195628_3196327_-	DUF484 family protein	NA	NA	NA	NA
WP_106473306.1\|3196476_3197130_-	fructose-6-phosphate aldolase	A0A127KMN5	Cyanophage	1.0e-48	48.1

DBSCAN-SWA_229

3212722 : 3213709

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473320.1\|3212722_3213709_+	D-glycerate dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	1.7e-18	26.8

DBSCAN-SWA_230

3219776 : 3220904

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474143.1\|3219776_3220904_+	alanine--glyoxylate aminotransferase family protein	A0A0N9QIZ2	Chrysochromulina_ericina_virus	2.3e-72	40.4

DBSCAN-SWA_231

3225657 : 3230828

Halovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473330.1\|3225657_3226833_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	1.9e-40	32.1
WP_106473331.1\|3227018_3227498_+	GatB/YqeY domain-containing protein	A0A2I7SAL1	Vibrio_phage	6.1e-06	30.0
WP_106473332.1\|3227537_3228344_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_106473333.1\|3228340_3229225_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_106473334.1\|3229277_3229997_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_106474144.1\|3230033_3230828_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.5e-28	37.1

DBSCAN-SWA_232

3242796 : 3243408

Emiliania_huxleyi_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473342.1\|3242796_3243408_+	N-acetylmuramidase	G8DH66	Emiliania_huxleyi_virus	6.1e-59	58.8

DBSCAN-SWA_233

3250709 : 3260778

Acinetobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473350.1\|3250709_3252227_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.1e-19	32.1
WP_106473351.1\|3252223_3253174_-	xanthine dehydrogenase accessory protein XdhC	NA	NA	NA	NA
WP_106473352.1\|3253163_3255506_-	xanthine dehydrogenase molybdopterin binding subunit	A0A0P0I429	Acinetobacter_phage	3.4e-214	50.6
WP_106473353.1\|3255502_3256909_-	xanthine dehydrogenase small subunit	A0A0P0IVM8	Acinetobacter_phage	1.3e-96	45.0
WP_106473354.1\|3257262_3260778_+	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	3.8e-177	34.1

DBSCAN-SWA_234

3280780 : 3281548

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473372.1\|3280780_3281548_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.4e-28	33.5

DBSCAN-SWA_235

3296784 : 3301781

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473388.1\|3296784_3299667_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	60.3
WP_106473389.1\|3299734_3300319_+	VOC family protein	NA	NA	NA	NA
WP_106473390.1\|3300320_3300722_-	hypothetical protein	NA	NA	NA	NA
WP_106473391.1\|3300908_3301781_-	3-hydroxyisobutyrate dehydrogenase	A0A077SLF7	Escherichia_phage	1.8e-19	31.3

DBSCAN-SWA_236

3309101 : 3309608

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473399.1\|3309101_3309608_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	4.3e-34	46.6

DBSCAN-SWA_237

3327295 : 3329047

Micromonas_pusilla_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474149.1\|3327295_3329047_-	acetolactate synthase 3 large subunit	G8DDL3	Micromonas_pusilla_virus	7.9e-51	28.4

DBSCAN-SWA_238

3357319 : 3358793

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473438.1\|3357319_3358111_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.8e-34	34.9
WP_106473439.1\|3358103_3358793_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.0e-38	42.4

DBSCAN-SWA_239

3363748 : 3367724

Indivirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473443.1\|3363748_3364336_+	riboflavin synthase	A0A1V0SE20	Indivirus	3.9e-18	35.7
WP_106473444.1\|3364518_3365646_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	5.8e-47	37.0
WP_106473445.1\|3365647_3366199_+	6,7-dimethyl-8-ribityllumazine synthase	NA	NA	NA	NA
WP_106473446.1\|3366195_3366678_+	transcription antitermination factor NusB	NA	NA	NA	NA
WP_106473447.1\|3366730_3367057_+	hypothetical protein	NA	NA	NA	NA
WP_106473448.1\|3367292_3367724_+	MmcB family DNA repair protein	A0A1C3NFG6	Phage_NCTB	7.7e-08	32.2

DBSCAN-SWA_240

3371668 : 3382382

Flavobacterium_phage(25.0%)

tRNA,integrase

attL 3376172:3376191|attR 3394682:3394701

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473452.1\|3371668_3373336_+	cytochrome c oxidase subunit I	R9VX24	Flavobacterium_phage	3.7e-05	32.7
WP_106473453.1\|3374153_3374402_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_106473454.1\|3374398_3375004_+	DUF882 domain-containing protein	A0A223VZI6	Agrobacterium_phage	1.0e-10	46.4
WP_149615545.1\|3375023_3376724_+	hypothetical protein	NA	NA	NA	NA
3376172:3376191	attL	NA	NA	NA	NA
WP_149615546.1\|3376734_3377220_-	hypothetical protein	NA	NA	NA	NA
WP_106473456.1\|3377324_3378356_-\|integrase	site-specific integrase	A0A2D1GMX8	Marinobacter_phage	2.7e-67	42.5
WP_106473457.1\|3378435_3379458_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_106473458.1\|3379489_3380314_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_106473459.1\|3380387_3380888_-	flavin reductase family protein	NA	NA	NA	NA
WP_106474154.1\|3380969_3382382_-	3'-5' exonuclease	K7RFY5	Vibrio_phage	1.1e-05	33.9
3394682:3394701	attR	NA	NA	NA	NA

DBSCAN-SWA_241

3387234 : 3389892

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473464.1\|3387234_3387918_-	adenylate kinase	A0A2K9L833	Tupanvirus	2.9e-09	41.4
WP_106473465.1\|3387930_3389892_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.6e-84	38.8

DBSCAN-SWA_242

3396718 : 3398248

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473469.1\|3396718_3398248_+	malonyl-CoA synthase	A0A2H4PQM9	Staphylococcus_phage	3.1e-35	28.3

DBSCAN-SWA_243

3403700 : 3404657

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473472.1\|3403700_3404657_-	tyrosine recombinase	A0A0F6SJK8	Mycobacterium_phage	5.0e-15	29.7

DBSCAN-SWA_244

3409258 : 3412648

Paracoccus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473477.1\|3409258_3409762_-	single-stranded DNA-binding protein	A0A0U2C0X4	Paracoccus_phage	1.5e-50	81.8
WP_106473478.1\|3409966_3410551_+	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	4.4e-30	50.4
WP_106473479.1\|3410560_3412648_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.2e-10	24.6

DBSCAN-SWA_245

3419443 : 3420178

Flavobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473486.1\|3419443_3420178_+	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	6.3e-18	37.0

DBSCAN-SWA_246

3431677 : 3434588

Roseobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473496.1\|3431677_3432397_+	response regulator transcription factor	F4YXP8	Roseobacter_phage	5.2e-17	51.6
WP_106474158.1\|3432467_3434588_+	NAD-dependent DNA ligase LigA	A0A1W6DX16	Sphingobium_phage	2.3e-113	38.8

DBSCAN-SWA_247

3455324 : 3456389

Roseobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473518.1\|3455324_3456389_+	DUF2793 domain-containing protein	F4YXU6	Roseobacter_phage	2.6e-20	31.9

DBSCAN-SWA_248

3460298 : 3472762

Powai_lake_megavirus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473523.1\|3460298_3461381_+	alpha/beta hydrolase	A0A167RJ59	Powai_lake_megavirus	1.3e-22	32.7
WP_106473524.1\|3461377_3461968_-	HD domain-containing protein	NA	NA	NA	NA
WP_106473525.1\|3461967_3462621_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_106473526.1\|3462788_3463250_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_106473527.1\|3463358_3464402_+	aminotransferase class V-fold PLP-dependent enzyme	A0A1X6WFP1	Pacmanvirus	2.3e-13	24.5
WP_106473528.1\|3464418_3465942_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_106473529.1\|3465934_3466126_+	hypothetical protein	NA	NA	NA	NA
WP_106474162.1\|3466181_3466934_+	Fe-S cluster assembly ATPase SufC	G3M9Y6	Bacillus_virus	3.8e-10	27.7
WP_106473530.1\|3466936_3468217_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_106473531.1\|3468216_3468702_+	YIP1 family protein	NA	NA	NA	NA
WP_106473532.1\|3468698_3469289_+	YIP1 family protein	NA	NA	NA	NA
WP_106473533.1\|3469281_3470502_+	cysteine desulfurase	Q2XUY6	environmental_halophage	5.3e-94	40.6
WP_106473534.1\|3470859_3471765_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_106473535.1\|3471859_3472762_+	manganese/iron ABC transporter ATP-binding protein	A0A1M7XV31	Cedratvirus	1.6e-15	28.3

DBSCAN-SWA_249

3489513 : 3494901

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473548.1\|3489513_3490638_-	putative 2-aminoethylphosphonate ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.7e-22	35.1
WP_106473549.1\|3490732_3491752_-	putative 2-aminoethylphosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_106473550.1\|3492025_3492625_-	biotin transporter BioY	NA	NA	NA	NA
WP_106473551.1\|3492815_3493073_+	adenylosuccinate lyase	NA	NA	NA	NA
WP_106473552.1\|3493077_3493491_-	trigger factor	NA	NA	NA	NA
WP_106473553.1\|3493587_3494901_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.3e-18	30.6

DBSCAN-SWA_250

3498790 : 3500239

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473556.1\|3498790_3500239_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.5e-90	40.6

DBSCAN-SWA_251

3504618 : 3508501

Mycobacterium_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474168.1\|3504618_3505686_+	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	2.1e-115	63.4
WP_106473559.1\|3505846_3508501_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.9e-72	37.4

DBSCAN-SWA_252

3514260 : 3518514

Deep-sea_thermophilic_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473564.1\|3514260_3514959_-	transcriptional repressor LexA	E5DV74	Deep-sea_thermophilic_phage	2.9e-12	35.2
WP_106473565.1\|3515041_3516214_-	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_106473566.1\|3516210_3516684_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_106473567.1\|3517491_3518514_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	6.0e-43	34.7

DBSCAN-SWA_253

3525945 : 3531414

Lactococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474169.1\|3525945_3526491_+	cold shock domain-containing protein	Q9AZD3	Lactococcus_phage	1.2e-05	39.3
WP_106473575.1\|3526490_3526955_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.2e-10	37.1
WP_106473576.1\|3527754_3531414_+	vitamin B12-dependent ribonucleotide reductase	A0A1X9SGV9	Bradyrhizobium_phage	0.0e+00	56.4

DBSCAN-SWA_254

3549572 : 3555621

Mycobacterium_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473586.1\|3549572_3550553_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	2.1e-130	70.6
WP_106473587.1\|3550560_3552693_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.1e-195	48.0
WP_106473588.1\|3552674_3553091_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	6.5e-12	34.4
WP_106473589.1\|3553095_3553317_-	glutaredoxin-like protein NrdH	V5UN81	Mycobacterium_phage	3.7e-14	50.7
WP_106473590.1\|3554107_3554971_+	hypothetical protein	NA	NA	NA	NA
WP_106473591.1\|3555021_3555621_-	HNH endonuclease	K4FCE1	Escherichia_phage	2.4e-07	34.0

DBSCAN-SWA_255

3559817 : 3560750

Enterobacteria_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473594.1\|3559817_3560750_-\|transposase	IS5 family transposase	Q1MVF0	Enterobacteria_phage	4.1e-46	35.4

DBSCAN-SWA_256

3575797 : 3577882

Organic_Lake_phycodnavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473599.1\|3575797_3577882_-	type I secretion system permease/ATPase	F2Y2R6	Organic_Lake_phycodnavirus	8.6e-20	32.3

DBSCAN-SWA_257

3587321 : 3588206

Caulobacter_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473603.1\|3587321_3588206_+	DUF1738 domain-containing protein	K4JTS1	Caulobacter_virus	1.2e-52	46.0

DBSCAN-SWA_258

3601871 : 3603005

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474177.1\|3601871_3603005_-	lytic transglycosylase domain-containing protein	A0A1P8CWQ1	Bacillus_phage	9.7e-26	56.4

DBSCAN-SWA_259

3606095 : 3606674

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473617.1\|3606095_3606674_-	lytic transglycosylase domain-containing protein	A0A1P8CWQ1	Bacillus_phage	9.0e-20	53.9

DBSCAN-SWA_260

3641703 : 3643071

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473643.1\|3641703_3643071_-	peptidoglycan DD-metalloendopeptidase family protein	S5M424	Bacillus_phage	9.0e-18	41.7

DBSCAN-SWA_261

3650651 : 3662960

Klosneuvirus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474181.1\|3650651_3651230_+	DUF924 domain-containing protein	A0A1V0SIY0	Klosneuvirus	5.1e-15	30.1
WP_106473647.1\|3651262_3651703_-	hypothetical protein	NA	NA	NA	NA
WP_106473648.1\|3651899_3653294_+	dihydrolipoyl dehydrogenase	NA	NA	NA	NA
WP_106473649.1\|3653365_3653707_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	9.1e-12	37.2
WP_106473650.1\|3653703_3654762_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_106473651.1\|3654758_3655190_-	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_106473652.1\|3655186_3655525_-	DUF952 domain-containing protein	NA	NA	NA	NA
WP_106473653.1\|3655656_3657234_+	multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase	A0A2R8FDL9	Cedratvirus	6.9e-38	28.6
WP_106473654.1\|3657237_3659004_-	sulfotransferase family protein	NA	NA	NA	NA
WP_106473655.1\|3659137_3659875_-	Bax inhibitor-1/YccA family protein	A0A1S5WLC9	Cowpox_virus	6.1e-05	26.6
WP_106473656.1\|3660037_3660259_-	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_106473657.1\|3660380_3661268_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_106473658.1\|3661241_3662234_-	NADPH:quinone oxidoreductase family protein	NA	NA	NA	NA
WP_106473659.1\|3662576_3662960_+	helix-turn-helix transcriptional regulator	K4K6E9	Caulobacter_phage	3.9e-19	45.5

DBSCAN-SWA_262

3668550 : 3670530

Tupanvirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473667.1\|3668550_3670530_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	7.9e-116	35.5

DBSCAN-SWA_263

3685545 : 3693579

Bacillus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473675.1\|3685545_3687357_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	4.8e-59	29.7
WP_106473676.1\|3687496_3689392_+	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	2.7e-20	26.5
WP_106473677.1\|3689407_3690331_+	alpha/beta hydrolase	L7RDF8	Acanthamoeba_polyphaga_moumouvirus	5.7e-24	29.3
WP_106473678.1\|3690337_3691174_-	nucleotide pyrophosphatase	NA	NA	NA	NA
WP_149615557.1\|3691317_3691932_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_106473679.1\|3691941_3693579_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.5e-19	31.2

DBSCAN-SWA_264

3701325 : 3703170

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473686.1\|3701325_3703170_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	5.9e-73	33.5

DBSCAN-SWA_265

3711057 : 3712674

Pandoravirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473693.1\|3711057_3711504_+	nucleoside deaminase	S4VYZ2	Pandoravirus	1.4e-07	48.1
WP_106473694.1\|3711987_3712674_-	N-acetylmuramoyl-L-alanine amidase	A0A076YN96	Rhizobium_phage	6.3e-12	31.1

DBSCAN-SWA_266

3717042 : 3719472

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473699.1\|3717042_3719472_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.3e-104	34.1

DBSCAN-SWA_267

3727886 : 3729764

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474193.1\|3727886_3728969_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.6e-28	33.2
WP_106473707.1\|3728984_3729764_-	heme ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	2.1e-11	29.1

DBSCAN-SWA_268

3743323 : 3747207

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473720.1\|3743323_3744118_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	8.9e-18	27.5
WP_106473721.1\|3744139_3744817_-	hypothetical protein	A0A1D8KGH6	Synechococcus_phage	1.1e-13	27.1
WP_149615558.1\|3744863_3745688_-	hypothetical protein	NA	NA	NA	NA
WP_106473723.1\|3745881_3747207_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	3.9e-18	23.4

DBSCAN-SWA_269

3756062 : 3756719

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474196.1\|3756062_3756719_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-26	41.3

DBSCAN-SWA_270

3763822 : 3765382

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473735.1\|3763822_3765382_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	3.4e-13	27.2

DBSCAN-SWA_271

3772667 : 3775599

uncultured_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473742.1\|3772667_3773216_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	1.7e-12	28.7
WP_106473743.1\|3773308_3773755_+	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_106473744.1\|3773799_3775101_+	2-methylcitrate dehydratase	NA	NA	NA	NA
WP_106473745.1\|3775125_3775599_-	CinA family protein	B5TK85	Pseudomonas_phage	3.9e-13	43.2

DBSCAN-SWA_272

3794102 : 3795329

Bathycoccus_sp._RCC1105_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106474198.1\|3794102_3795329_-	aminotransferase	E5ES42	Bathycoccus_sp._RCC1105_virus	1.2e-16	32.1

DBSCAN-SWA_273

3801030 : 3810090

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473766.1\|3801030_3802743_+	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.8e-23	23.9
WP_106473767.1\|3802795_3803566_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.3e-05	28.6
WP_106473768.1\|3803575_3804448_-	acyl-CoA thioesterase II	NA	NA	NA	NA
WP_106473769.1\|3804453_3806430_-	acetoacetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.3e-17	23.1
WP_106474199.1\|3806426_3807602_-	serine hydrolase	A0A2P1JQM9	Mycobacterium_phage	3.0e-06	28.6
WP_106474200.1\|3807664_3808474_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_106473770.1\|3808630_3809332_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.2e-07	23.9
WP_106473771.1\|3809331_3810090_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.3e-15	28.3

DBSCAN-SWA_274

3822874 : 3823630

Aeromonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473785.1\|3822874_3823630_+	LuxR family transcriptional regulator	A0A1I9KF49	Aeromonas_phage	2.1e-08	26.8

DBSCAN-SWA_275

3828469 : 3830906

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473792.1\|3828469_3829735_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.1e-93	46.9
WP_106473793.1\|3829799_3830906_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.6e-52	38.7

DBSCAN-SWA_276

3846369 : 3847857

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473813.1\|3846369_3847857_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	1.4e-45	37.9

DBSCAN-SWA_277

3863669 : 3878936

Streptococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473828.1\|3863669_3864947_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.4e-144	61.7
WP_106473829.1\|3864943_3865894_-	DMT family transporter	NA	NA	NA	NA
WP_106473830.1\|3866006_3867047_+	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_106473831.1\|3867043_3867466_-	transcriptional repressor	NA	NA	NA	NA
WP_106474205.1\|3867834_3869139_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	9.4e-49	32.2
WP_106473832.1\|3869147_3869984_-	tellurite resistance TerB family protein	NA	NA	NA	NA
WP_106473833.1\|3870066_3870777_-	endonuclease	NA	NA	NA	NA
WP_106473834.1\|3870867_3871746_+	DMT family transporter	NA	NA	NA	NA
WP_106473835.1\|3871748_3873167_-	YdiU family protein	A0A075BSJ0	Microcystis_phage	2.1e-49	39.9
WP_106473836.1\|3873236_3873686_+	cupin domain-containing protein	A0A291ATU0	Pandoravirus	2.7e-24	46.2
WP_106473837.1\|3873707_3874832_-	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_106473838.1\|3874895_3876149_+\|tRNA	tyrosine--tRNA ligase	A0A1S6UA79	Serratia_phage	9.6e-59	35.6
WP_106473839.1\|3876269_3877025_+	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
WP_106473840.1\|3877124_3878936_-	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.4e-33	25.5

DBSCAN-SWA_278

3883580 : 3891564

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106473846.1\|3883580_3883883_+	integration host factor subunit alpha	A0A1P8CWT5	Bacillus_phage	2.3e-11	37.4
WP_106473847.1\|3883905_3884733_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_106473848.1\|3884925_3886017_+	2'-deoxycytidine 5'-triphosphate deaminase	NA	NA	NA	NA
WP_106474207.1\|3886013_3887090_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	5.2e-37	31.9
WP_106473849.1\|3887110_3887578_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_106473850.1\|3887701_3888115_-	YjbQ family protein	NA	NA	NA	NA
WP_149615559.1\|3888131_3888515_-	hypothetical protein	NA	NA	NA	NA
WP_106473852.1\|3888535_3888964_-	hypothetical protein	NA	NA	NA	NA
WP_106473853.1\|3888968_3889373_-	hypothetical protein	NA	NA	NA	NA
WP_106473854.1\|3889581_3891564_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.8e-35	28.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP043620

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 11441

Rhizobium_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615729.1\|601_1813_+	replication initiation protein RepC	L7TKN6	Rhizobium_phage	5.7e-24	29.5
WP_149615697.1\|1993_4162_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_008335991.1\|4750_5155_+	single-stranded DNA-binding protein	Q6V7S6	Burkholderia_virus	1.5e-16	41.6
WP_149615730.1\|5294_6131_-	hypothetical protein	NA	NA	NA	NA
WP_149615698.1\|6737_7937_+	DUF932 domain-containing protein	A0A1V0DX75	Synechococcus_virus	1.7e-68	41.2
WP_149615699.1\|8065_8506_+	DNA repair protein RadC	NA	NA	NA	NA
WP_149615700.1\|8616_9135_+	DNA repair protein RadC	NA	NA	NA	NA
WP_149615701.1\|9230_9722_+	hypothetical protein	NA	NA	NA	NA
WP_149615702.1\|9732_10110_+	hypothetical protein	U5J9H1	Bacillus_phage	7.4e-31	54.1
WP_149615703.1\|10111_10309_+	hypothetical protein	NA	NA	NA	NA
WP_149615704.1\|10384_10804_+	hypothetical protein	NA	NA	NA	NA
WP_149615705.1\|10796_11441_+	antitoxin of toxin-antitoxin stability system	A0A2I6PI07	Pseudomonas_phage	1.1e-29	37.1

DBSCAN-SWA_2

18218 : 27201

Brevibacillus_phage(25.0%)

integrase

attL 18095:18154|attR 24318:24493

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
18095:18154	attL	NA	NA	NA	NA
WP_149615622.1\|18218_19745_+\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	1.4e-11	26.1
WP_149615692.1\|19741_20653_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149615621.1\|20649_21654_+\|integrase	tyrosine-type recombinase/integrase	A0A2K9VH72	Gordonia_phage	9.2e-12	28.7
WP_149615620.1\|21693_24135_-	DEAD/DEAH box helicase family protein	A0A2K9R7J3	Dishui_lake_phycodnavirus	3.0e-32	29.8
WP_149615709.1\|26169_27201_+	DNA primase	A0A0H5AWB1	Pseudomonas_phage	2.2e-16	30.7
24318:24493	attR	NA	NA	NA	NA

DBSCAN-SWA_3

31264 : 35350

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615714.1\|31264_35350_-	restriction endonuclease	A0A1B1IUC6	uncultured_Mediterranean_phage	1.4e-50	25.4

DBSCAN-SWA_4

49839 : 51006

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615725.1\|49839_51006_-	transglycosylase SLT domain-containing protein	A0A1P8CWQ1	Bacillus_phage	2.0e-26	51.1

DBSCAN-SWA_5

54207 : 54891

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615731.1\|54207_54891_-	transglycosylase SLT domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	6.3e-20	55.8

DBSCAN-SWA_6

64925 : 66299

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_026155631.1\|64925_66299_+	M23 family metallopeptidase	G9BW84	Planktothrix_phage	9.0e-18	43.9

DBSCAN-SWA_7

70169 : 77720

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_018001712.1\|70169_72524_-	cation-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.2e-116	40.7
WP_038068706.1\|72706_72991_+	hypothetical protein	NA	NA	NA	NA
WP_026155629.1\|73016_73682_-	L,D-transpeptidase	NA	NA	NA	NA
WP_038068700.1\|74213_75284_-	hypothetical protein	NA	NA	NA	NA
WP_071974352.1\|75510_76392_+	recombinase family protein	A0A0C4UR34	Shigella_phage	3.4e-34	56.8
WP_043754416.1\|76526_77720_+	plasmid partitioning protein RepA	A0A240F4U1	Ochrobactrum_phage	9.6e-117	53.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP043619

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

22118 : 85071

Bacillus_phage(15.38%)

transposase,integrase

attL 80436:80495|attR 86659:86834

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149615585.1\|22118_23636_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2H4JGQ6	uncultured_Caudovirales_phage	1.1e-11	22.7
WP_149615586.1\|24956_25157_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_149615587.1\|25199_25931_-	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_149615588.1\|25932_26415_-	c-type cytochrome	NA	NA	NA	NA
WP_007803406.1\|26411_27806_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_007803405.1\|27849_28767_-	cytochrome c	NA	NA	NA	NA
WP_007803403.1\|28769_29363_-	cytochrome c	NA	NA	NA	NA
WP_007803401.1\|29732_30191_-	cytochrome c	NA	NA	NA	NA
WP_149615589.1\|30219_30780_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_043754567.1\|30935_31238_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_009807485.1\|31521_33651_+	suppressor for copper-sensitivity B precursor	NA	NA	NA	NA
WP_149615590.1\|33679_34831_-	c-type cytochrome biogenesis protein CcmI	NA	NA	NA	NA
WP_009807484.1\|34827_35301_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_009807483.1\|35297_35864_-	DsbE family thiol:disulfide interchange protein	NA	NA	NA	NA
WP_149615591.1\|35872_37873_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_009807481.1\|37938_38130_-	membrane protein	NA	NA	NA	NA
WP_149615592.1\|38179_39646_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_078523120.1\|39645_40368_-	response regulator	W8CYM9	Bacillus_phage	2.6e-32	38.8
WP_146681743.1\|40877_42228_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	6.2e-11	31.0
WP_149615593.1\|42635_43502_+	AAA family ATPase	NA	NA	NA	NA
WP_149615594.1\|43498_44509_+	TniQ family protein	NA	NA	NA	NA
WP_078523268.1\|44525_45137_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.2e-15	28.1
WP_078523244.1\|45184_46069_-	DUF1403 family protein	NA	NA	NA	NA
WP_149615595.1\|46226_47324_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149615596.1\|47330_47666_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_149615686.1\|47662_47920_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_149615687.1\|48046_48583_+	hypothetical protein	NA	NA	NA	NA
WP_149615597.1\|48949_50149_+	plasmid partitioning protein RepA	A0A240F4U1	Ochrobactrum_phage	7.2e-88	46.6
WP_149615598.1\|50133_51117_+	plasmid partitioning protein RepB	A0A240F4U0	Ochrobactrum_phage	1.2e-24	27.7
WP_149615599.1\|51357_52413_+	replication initiator RepC	NA	NA	NA	NA
WP_149615600.1\|52519_54688_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_149615601.1\|56107_57160_+	hypothetical protein	NA	NA	NA	NA
WP_149615602.1\|57914_58319_+	single-stranded DNA-binding protein	Q6V7S6	Burkholderia_virus	1.5e-16	42.5
WP_149615603.1\|58579_59542_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149615604.1\|59747_61247_+	DUF1214 domain-containing protein	NA	NA	NA	NA
WP_149615605.1\|61308_62832_+	DUF1254 domain-containing protein	M1I2Z8	Paramecium_bursaria_Chlorella_virus	7.0e-11	35.1
WP_149615688.1\|62960_63692_+	transporter	NA	NA	NA	NA
WP_149615689.1\|63954_64866_+	Hint domain-containing protein	NA	NA	NA	NA
WP_149615606.1\|64941_66141_+	DUF932 domain-containing protein	A0A1V0DX75	Synechococcus_virus	5.8e-69	41.2
WP_149615607.1\|66267_66708_+	DNA repair protein RadC	NA	NA	NA	NA
WP_149615608.1\|66818_67337_+	DNA repair protein RadC	NA	NA	NA	NA
WP_149615609.1\|67434_67926_+	hypothetical protein	NA	NA	NA	NA
WP_149615610.1\|68275_69697_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_149615611.1\|69693_71520_+	hypothetical protein	NA	NA	NA	NA
WP_149615690.1\|71675_73664_+	hypothetical protein	NA	NA	NA	NA
WP_149615612.1\|73660_74086_+	hypothetical protein	NA	NA	NA	NA
WP_149615613.1\|74274_74496_+	hypothetical protein	U5J9H1	Bacillus_phage	7.2e-10	50.0
WP_149615614.1\|74497_74695_+	hypothetical protein	NA	NA	NA	NA
WP_149615615.1\|74769_75189_+	hypothetical protein	NA	NA	NA	NA
WP_149615616.1\|75181_75826_+	antitoxin of toxin-antitoxin stability system	A0A126DJL2	Acinetobacter_phage	3.5e-20	31.9
WP_149615617.1\|75854_76058_-	hypothetical protein	NA	NA	NA	NA
WP_149615691.1\|76076_76676_-	mobile mystery protein B	NA	NA	NA	NA
WP_149615618.1\|76678_77140_-	transcriptional regulator	NA	NA	NA	NA
WP_149615619.1\|77342_77639_-	hypothetical protein	NA	NA	NA	NA
80436:80495	attL	NA	NA	NA	NA
WP_149615620.1\|80677_83119_+	DEAD/DEAH box helicase family protein	A0A2K9R7J3	Dishui_lake_phycodnavirus	3.0e-32	29.8
WP_149615621.1\|83158_84163_-\|integrase	tyrosine-type recombinase/integrase	A0A2K9VH72	Gordonia_phage	9.2e-12	28.7
WP_149615692.1\|84159_85071_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
86659:86834	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage