CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP027222	Escherichia coli strain 2015C-3101 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0
NZ_CP027221	Escherichia coli strain 2015C-3101 chromosome, complete genome	3 crisprs	cas14i,DEDDh,DinG,PrimPol,cas3,c2c9_V-U4,csa3,cas2,cas1,cas5,cas7,cse2gr11,cas8e	6	17
NZ_CP027223	Escherichia coli strain 2015C-3101 plasmid unnamed2	0 crisprs	NA	0	3

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP027221_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027221_1

3999406-3999739

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder

5 spacers

cas2,cas1,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP027221_1

>merge|NZ_CP027221|1|3999406-3999739|CRT,PILER-CR,CRISPRCasFinder
GGGAGTTCTACCGCAGGGGCGGGGAATTCTAAGTGATATCCATCATCGCATCCAGTGCGCCCGGTTTATCCCCGCTGACGCGGGGAACACAAAACCAAACTTCTCCATAAATTCCATAGCCGCGGTTTATCCCCGCTGGCGCGGGGAACACGAGAGTGCTGACAGGTGTCTCGATTACCTGATCGGTTTATCCCCGCTGGCGCGGGGAACACGAACGCAATATCACGGCGTTCTGCGGCCTCGGCGGTTTATCCCCGCTGGCGCGGGGAACACGTCGGGCCGGGTAAGTGAACCTGTCGGTTTTCCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027221|1|1|3999406-3999739|CRT
GGGAGTTCTACCGCAGGGGCGGGGAATTC	TAAGTGATATCCATCATCGCATCCAGTGCGCC
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027221|1|1|3999467-3999739|PILER-CR
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027221|1|1|3999467-3999739|CRISPRCasFinder
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027221.1\|WP_000490429.1\|3998347_3999385_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP027221.1\|WP_001290688.1\|4009814_4011527_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP027221.1\|WP_001219242.1\|3993068_3993548_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP027221.1\|WP_000039843.1\|4009006_4009741_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP027221.1\|WP_000085038.1\|4001676_4002423_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP027221.1\|WP_000517476.1\|3994276_3994588_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP027221.1\|WP_001233921.1\|4005696_4008396_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP027221.1\|WP_000144863.1\|4000128_4001049_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP027221.1\|WP_106898662.1\|3995746_3997186_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP027221.1\|WP_000063176.1\|3999835_4000129_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP027221.1\|WP_000029342.1\|4003500_4004040_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP027221.1\|WP_001173673.1\|3995154_3995760_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP027221.1\|WP_001084109.1\|4004036_4005599_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP027221.1\|WP_000956458.1\|4008589_4008742_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP027221.1\|WP_001295182.1\|3991280_3992042_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP027221.1\|WP_000568972.1\|3992022_3993072_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP027221.1\|WP_000246138.1\|3993547_3994258_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP027221.1\|WP_000206431.1\|4002433_4003489_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP027221.1\|WP_000372108.1\|3997187_3998096_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP027221.1\|WP_001246104.1\|3994781_3995105_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891

Protein	Function_ID	Function_description	E-value
NZ_CP027221.1\|WP_000490429.1\|3998347_3999385_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP027221.1\|WP_001290688.1\|4009814_4011527_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP027221.1\|WP_001219242.1\|3993068_3993548_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP027221.1\|WP_000039843.1\|4009006_4009741_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP027221.1\|WP_000085038.1\|4001676_4002423_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	3.02728e-49
NZ_CP027221.1\|WP_000517476.1\|3994276_3994588_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP027221.1\|WP_001233921.1\|4005696_4008396_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.73288e-179
NZ_CP027221.1\|WP_000144863.1\|4000128_4001049_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	4.23259e-157
NZ_CP027221.1\|WP_106898662.1\|3995746_3997186_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP027221.1\|WP_000063176.1\|3999835_4000129_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP027221.1\|WP_000029342.1\|4003500_4004040_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	7.30002e-26
NZ_CP027221.1\|WP_001173673.1\|3995154_3995760_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP027221.1\|WP_001084109.1\|4004036_4005599_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP027221.1\|WP_000956458.1\|4008589_4008742_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP027221.1\|WP_001295182.1\|3991280_3992042_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP027221.1\|WP_000568972.1\|3992022_3993072_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP027221.1\|WP_000246138.1\|3993547_3994258_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP027221.1\|WP_000206431.1\|4002433_4003489_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	6.10696e-155
NZ_CP027221.1\|WP_000372108.1\|3997187_3998096_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP027221.1\|WP_001246104.1\|3994781_3995105_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52

>NZ_CP027221.1|WP_000490429.1|3998347_3999385_+|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP027221.1|WP_000372108.1|3997187_3998096_-|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP027221.1|WP_106898662.1|3995746_3997186_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTSGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGINNGAA
>NZ_CP027221.1|WP_001173673.1|3995154_3995760_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP027221.1|WP_001246104.1|3994781_3995105_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP027221.1|WP_000517476.1|3994276_3994588_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP027221.1|WP_000246138.1|3993547_3994258_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP027221.1|WP_001219242.1|3993068_3993548_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP027221.1|WP_000568972.1|3992022_3993072_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEYILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLNDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP027221.1|WP_001295182.1|3991280_3992042_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>NZ_CP027221.1|WP_000063176.1|3999835_4000129_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP027221.1|WP_000144863.1|4000128_4001049_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPQPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRG
>NZ_CP027221.1|WP_000085038.1|4001676_4002423_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGGDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGAWLSKEEPCTSQE
>NZ_CP027221.1|WP_000206431.1|4002433_4003489_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWSAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP027221.1|WP_000029342.1|4003500_4004040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP027221.1|WP_001084109.1|4004036_4005599_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGTAWQFLLGLLQTSFAPKNHGRWDDIWQDGLEAEKLREALLSLEHAFQFGADSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP027221.1|WP_001233921.1|4005696_4008396_-|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKNRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIESPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>NZ_CP027221.1|WP_000956458.1|4008589_4008742_-|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP027221.1|WP_000039843.1|4009006_4009741_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP027221.1|WP_001290688.1|4009814_4011527_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDHEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD

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Crispr_ID: NZ_CP027221_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027221_2

4025440-4025834

Unclear

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACA	PILER-CR

6 spacers

The CRISPR arrays of NZ_CP027221_2

>merge|NZ_CP027221|2|4025440-4025834|CRISPRCasFinder,CRT,PILER-CR
TGGTTTATCCCCGCTGGCGCGGGGAACTCGACAGAACGGCCTCAGTAGTCTCGTCAGGCTCCGGTTTATCCCCGCTGGCGCGGGGAGCTCTACGTGAAGAATATTTGCAACACCCGCAAGAACGGTTTATCCCCGCTGGCGCGGGGAACACTCCAACCTTCCATGAGATACGCGCATTAGCGGCGGTTTATCCCCGCTGGCGCGGGGAACACCGTGACCGCCTGTACACGCTGTAATGGCTCACCGGTTTATCCCCGCTGGCGCGGGGAACACACACTATCCGGGCGGTATTACGCCCAAATATCCGGTTTATCCCCGCTGGCGCGGGGAACACCTGCCGGGTGAAACCACTCGCGGCAGATCTTGCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027221|2|2|4025440-4025834|CRISPRCasFinder
TGGTTTATCCCCGCTGGCGCGGGGAACTC	GACAGAACGGCCTCAGTAGTCTCGTCAGGCTC
CGGTTTATCCCCGCTGGCGCGGGGAGCTC	TACGTGAAGAATATTTGCAACACCCGCAAGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCCAACCTTCCATGAGATACGCGCATTAGCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGTGACCGCCTGTACACGCTGTAATGGCTCAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACACTATCCGGGCGGTATTACGCCCAAATATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGCCGGGTGAAACCACTCGCGGCAGATCTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027221|2|2|4025440-4025832|CRT
TGGTTTATCCCCGCTGGCGCGGGGAAC	TCGACAGAACGGCCTCAGTAGTCTCGTCAGGCTC
CGGTTTATCCCCGCTGGCGCGGGGAGC	TCTACGTGAAGAATATTTGCAACACCCGCAAGAA
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACTCCAACCTTCCATGAGATACGCGCATTAGCGG
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACCGTGACCGCCTGTACACGCTGTAATGGCTCAC
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACACACTATCCGGGCGGTATTACGCCCAAATATC
CGGTTTATCCCCGCTGGCGCGGGGAAC	ACCTGCCGGGTGAAACCACTCGCGGCAGATCTTG
CGGTTTATCCCCGCTGGCGCGGGGAAC

>NZ_CP027221|2|2|4025501-4025833|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAGCT	CTACGTGAAGAATATTTGCAACACCCGCAAGAACGG
TTTATCCCCGCTGGCGCGGGGAACACTC	CAACCTTCCATGAGATACGCGCATTAGCGGCGG
TTTATCCCCGCTGGCGCGGGGAACACCG	TGACCGCCTGTACACGCTGTAATGGCTCACCGG
TTTATCCCCGCTGGCGCGGGGAACACAC	ACTATCCGGGCGGTATTACGCCCAAATATCCGG
TTTATCCCCGCTGGCGCGGGGAACACCT	GCCGGGTGAAACCACTCGCGGCAGATCTTGCGG
TTTATCCCCGCTGGCGCGGGGAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027221.1\|WP_001071648.1\|4031320_4032112_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP027221.1\|WP_000581937.1\|4032517_4032766_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP027221.1\|WP_001199970.1\|4026173_4026845_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP027221.1\|WP_001288224.1\|4026983_4027124_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_001098105.1\|4017960_4019298_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP027221.1\|WP_000186445.1\|4036482_4039239_+\|two-component-sensor-histidine-kinase-BarA	unknown	unknown	gnl\|CDD\|236848
NZ_CP027221.1\|WP_000021329.1\|4020915_4021701_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP027221.1\|WP_001130266.1\|4015623_4016199_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP027221.1\|WP_001341835.1\|4017203_4017983_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP027221.1\|WP_000039753.1\|4023322_4024801_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP027221.1\|WP_000254745.1\|4032182_4032518_-\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP027221.1\|WP_000036723.1\|4028069_4029368_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP027221.1\|WP_000210878.1\|4029455_4031093_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP027221.1\|WP_001164569.1\|4022019_4023297_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP027221.1\|WP_000059312.1\|4019391_4020846_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP027221.1\|WP_001268451.1\|4027137_4028010_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP027221.1\|WP_000109367.1\|4015346_4015607_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP027221.1\|WP_000226815.1\|4032843_4035078_-\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP027221.1\|WP_001299098.1\|4014084_4015356_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP027221.1\|WP_001341834.1\|4016346_4017207_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936

Protein	Function_ID	Function_description	E-value
NZ_CP027221.1\|WP_000581937.1\|4032517_4032766_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP027221.1\|WP_001199970.1\|4026173_4026845_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.73859e-155
NZ_CP027221.1\|WP_001071648.1\|4031320_4032112_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP027221.1\|WP_001098105.1\|4017960_4019298_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
NZ_CP027221.1\|WP_000186445.1\|4036482_4039239_+\|two-component-sensor-histidine-kinase-BarA	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	0
NZ_CP027221.1\|WP_000021329.1\|4020915_4021701_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.61186e-139
NZ_CP027221.1\|WP_001130266.1\|4015623_4016199_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP027221.1\|WP_001341835.1\|4017203_4017983_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	3.2021e-62
NZ_CP027221.1\|WP_000039753.1\|4023322_4024801_+\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.84635e-108
NZ_CP027221.1\|WP_000254745.1\|4032182_4032518_-\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NZ_CP027221.1\|WP_000036723.1\|4028069_4029368_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP027221.1\|WP_000210878.1\|4029455_4031093_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP027221.1\|WP_001164569.1\|4022019_4023297_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	3.54023e-29
NZ_CP027221.1\|WP_000059312.1\|4019391_4020846_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.25325e-82
NZ_CP027221.1\|WP_001268451.1\|4027137_4028010_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.01855e-100
NZ_CP027221.1\|WP_000109367.1\|4015346_4015607_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	8.55479e-42
NZ_CP027221.1\|WP_000226815.1\|4032843_4035078_-\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP027221.1\|WP_001299098.1\|4014084_4015356_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	2.77152e-127
NZ_CP027221.1\|WP_001341834.1\|4016346_4017207_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.55254e-89

>NZ_CP027221.1|WP_000039753.1|4023322_4024801_+|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPYADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP027221.1|WP_001164569.1|4022019_4023297_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEVRTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP027221.1|WP_000021329.1|4020915_4021701_-|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDSMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP027221.1|WP_000059312.1|4019391_4020846_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP027221.1|WP_001098105.1|4017960_4019298_-|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP027221.1|WP_001341835.1|4017203_4017983_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRIEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP027221.1|WP_001341834.1|4016346_4017207_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAVKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP027221.1|WP_001130266.1|4015623_4016199_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP027221.1|WP_000109367.1|4015346_4015607_+|ferredoxin-family-protein
MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP027221.1|WP_001299098.1|4014084_4015356_+|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEEEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKPVPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL
>NZ_CP027221.1|WP_001199970.1|4026173_4026845_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP027221.1|WP_001288224.1|4026983_4027124_+|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDDESKITDAAVNLFIQI
>NZ_CP027221.1|WP_001268451.1|4027137_4028010_+|YgcG-family-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKFAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVYISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGKSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>NZ_CP027221.1|WP_000036723.1|4028069_4029368_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP027221.1|WP_000210878.1|4029455_4031093_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP027221.1|WP_001071648.1|4031320_4032112_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP027221.1|WP_000254745.1|4032182_4032518_-|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP027221.1|WP_000581937.1|4032517_4032766_-|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP027221.1|WP_000226815.1|4032843_4035078_-|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP027221.1|WP_000186445.1|4036482_4039239_+|two-component-sensor-histidine-kinase-BarA
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVMNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG

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Crispr_ID: NZ_CP027221_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027221_3

4142955-4143044

Orphan

Consensus_repeat	Method
AAAAATGTCTAAAGCCCCTTTAGATAAAAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP027221_3

>merge|NZ_CP027221|3|4142955-4143044|CRISPRCasFinder
AAAAATGTCTAAAGCCCCTTTAGATAAAAATTACACTTTTTTAGAGATGAAAAAGGTATCAAAAATGTCTAAAGCCCTTTAGATAAAAAT

>NZ_CP027221|3|3|4142955-4143044|CRISPRCasFinder
AAAAATGTCTAAAGCCCCTTTAGATAAAAAT	TACACTTTTTTAGAGATGAAAAAGGTAT
CAAAAATGTCTAAAGCCCTTTAGATAAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027221.1\|WP_000038144.1\|4139634_4140015_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_001272558.1\|4146387_4147143_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|236782
NZ_CP027221.1\|WP_000388150.1\|4147557_4149855_+\|xanthine-dehydrogenase-molybdenum-binding-subunit-XdhA	unknown	unknown	gnl\|CDD\|236637
NZ_CP027221.1\|WP_001075361.1\|4140609_4141275_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_001180367.1\|4137760_4137976_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_000608393.1\|4139371_4139593_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_001570270.1\|4145531_4145738_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_000459182.1\|4149865_4150744_+\|xanthine-dehydrogenase-FAD-binding-subunit-XdhB	unknown	unknown	gnl\|CDD\|182175
NZ_CP027221.1\|WP_000417770.1\|4151259_4153038_-\|sigma-54-dependent-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350
NZ_CP027221.1\|WP_053887713.1\|4139063_4139372_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_000169008.1\|4138854_4139064_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_001016605.1\|4150740_4151220_+\|xanthine-dehydrogenase-iron-sulfur-binding-subunit-XdhC	unknown	unknown	gnl\|CDD\|182139
NZ_CP027221.1\|WP_001273868.1\|4143973_4144525_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP027221.1\|WP_000872470.1\|4141422_4141605_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_001232281.1\|4145177_4145498_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|316506
NZ_CP027221.1\|WP_000110493.1\|4154761_4155958_+\|diaminopropionate-ammonia-lyase	unknown	unknown	gnl\|CDD\|274631
NZ_CP027221.1\|WP_000974765.1\|4137386_4137758_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_001303128.1\|4153516_4154704_+\|knotted-carbamoyltransferase-YgeW	unknown	unknown	gnl\|CDD\|235961
NZ_CP027221.1\|WP_000151767.1\|4140136_4140343_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027221.1\|WP_000876741.1\|4140339_4140597_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP027221.1\|WP_000417770.1\|4151259_4153038_-\|sigma-54-dependent-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	0
NZ_CP027221.1\|WP_000459182.1\|4149865_4150744_+\|xanthine-dehydrogenase-FAD-binding-subunit-XdhB	gnl\|CDD\|182175	PRK09971, PRK09971, xanthine dehydrogenase subunit XdhB; Provisional.	0
NZ_CP027221.1\|WP_001272558.1\|4146387_4147143_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|236782	PRK10871, nlpD, murein hydrolase activator NlpD.	4.23289e-75
NZ_CP027221.1\|WP_000388150.1\|4147557_4149855_+\|xanthine-dehydrogenase-molybdenum-binding-subunit-XdhA	gnl\|CDD\|236637	PRK09970, PRK09970, xanthine dehydrogenase subunit XdhA; Provisional.	0
NZ_CP027221.1\|WP_001273868.1\|4143973_4144525_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	7.12926e-55
NZ_CP027221.1\|WP_001303128.1\|4153516_4154704_+\|knotted-carbamoyltransferase-YgeW	gnl\|CDD\|235961	PRK07200, PRK07200, aspartate/ornithine carbamoyltransferase family protein; Validated.	0
NZ_CP027221.1\|WP_001232281.1\|4145177_4145498_+\|hypothetical-protein	gnl\|CDD\|316506	pfam13992, YecR, YecR-like lipoprotein. The YecR-like family of lipoproteins includes the YecR protein from E. coli. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are approximately 110 amino acids in length.	5.35087e-25
NZ_CP027221.1\|WP_000110493.1\|4154761_4155958_+\|diaminopropionate-ammonia-lyase	gnl\|CDD\|274631	TIGR03528, 2_3_DAP_am_ly, diaminopropionate ammonia-lyase. Members of this protein family are the homodimeric, pyridoxal phosphate enzyme diaminopropionate ammonia-lyase, which adds water to remove two amino groups, leaving pyruvate.	0
NZ_CP027221.1\|WP_001016605.1\|4150740_4151220_+\|xanthine-dehydrogenase-iron-sulfur-binding-subunit-XdhC	gnl\|CDD\|182139	PRK09908, PRK09908, xanthine dehydrogenase iron sulfur-binding subunit XdhC.	1.63023e-101

>NZ_CP027221.1|WP_000872470.1|4141422_4141605_-|hypothetical-protein
MKWYTPEHVVEAFKKGELTRHQVRMNRNTARRCGYPEREKCFDDALKIIDELRKAEAEKE
>NZ_CP027221.1|WP_001075361.1|4140609_4141275_-|hypothetical-protein
MNQNTKTIAEAKAQCLNKKDSKQTYVVVEQWLKMFKKWFSPSGKEYTATLPAVEIYSYVAGFNEQGQECYANQKTLANIGMVSDRQVRNIINMFIDMGVLSVEARDGQTSLYKALPFTDAHITPPEDVKTSVNVEQPAPETQEPLEATHSIEQETQAEITEQSDLFTWLISIDSQKPMQEETENFIKRALTSKRIILEDDAFNALMIALRKESEIYDSIPF
>NZ_CP027221.1|WP_000876741.1|4140339_4140597_-|hypothetical-protein
MKYNLTLNKRTFEITESGYTLAKQLADSNYELPAIISFQELPHSKEHTQHWLNHLSHFGVIKYEAVNSQTFRLLEISPFELWVAL
>NZ_CP027221.1|WP_000151767.1|4140136_4140343_-|hypothetical-protein
MTIFDSEFSQETFLQYLRERTGMILFDSEFSGVVGEQFLYALLDSLSKQGLLQYTKTHMKAFRIDSVA
>NZ_CP027221.1|WP_000038144.1|4139634_4140015_-|hypothetical-protein
MSKKKGKKNVITTIGEACDQYALNNPRKYNYEHDAQPGEELIFILEEPSPELTDEELSLIQSMDGVYFNPRPRKTTVIDSSLLKRWQCLGFQDMHHFRGYMALNSLQYAGVRETELLLLDKIKIDD
>NZ_CP027221.1|WP_000608393.1|4139371_4139593_-|hypothetical-protein
MINKAILETTTFHDLKLLSECFISLIERAQEENDLGLLDDIIDNIATYKIPLTIAMKKAREAQQQLEQSEEVA
>NZ_CP027221.1|WP_053887713.1|4139063_4139372_-|hypothetical-protein
MSEVHNVTIEMMDLVIDLQKAVNAALTFPSELTITQAVINLESTREALQLLIAACEESEGAQIEADDLSNLIIVIHDTTEIMKEAVADLQPLINELIDKANN
>NZ_CP027221.1|WP_000169008.1|4138854_4139064_-|hypothetical-protein
MTKTKRVRLLALTEEGKAGNCFTVGKVYTGLLDTYTRLMHVTDDNGNDQTIVLDGNCVFGEWELTTEKS
>NZ_CP027221.1|WP_001180367.1|4137760_4137976_-|hypothetical-protein
MQNLILKNGNEELVITDETFNATAYMLGITPTELKKHCDKLFKSADEQKPTMQDLIKAKAEQIKQSKKGNY
>NZ_CP027221.1|WP_000974765.1|4137386_4137758_-|hypothetical-protein
MAIINMSDLFPVRKSFTDIVSYATDEFGCVQSFTVDLAVDVECGDLITSDGAEYVSGGDVLVVVSDAVSAGDAKTVNVLRSNAGLVCIKSDALNVEGAVKEAAIAALAAKGFQMAGFNTVFTS
>NZ_CP027221.1|WP_001273868.1|4143973_4144525_+|recombinase-family-protein
MANIGYIRVSTVQQNTDRQLAGVTLDKVFEDKASGKNTQRPQFEAMMNYVREGDVLHVHSIDRLCRNTADLLATVEQLTERGVSVHFHKEDFKTGKNSPAGNMMLTVLAAVAQMEREMMLERQREGIAAAKAAGRIAKRGNGKAIDRAGIAAALANGGSIRSVAKDFSVSTQTVQRIKKEQEA
>NZ_CP027221.1|WP_001232281.1|4145177_4145498_+|hypothetical-protein
MRKSLMLLLASTLIISGCATKKQLVPTGGSKSDGTVRMSYSYGMFESPVVDPQQGMNAAKARCAAWGYSGAEPFGGFTSQCSQPSSSGCMQTLVTIEYQCTGDIKK
>NZ_CP027221.1|WP_001570270.1|4145531_4145738_-|hypothetical-protein
MTVSYKITYEHRDGDQIRMEEVLFHSEHEPTKDEIHDAVRKDTVRFNSPSNGVTAVSGFKVISVVPVP
>NZ_CP027221.1|WP_001272558.1|4146387_4147143_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTVKRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSSTRKSTAKSTTKTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYAAGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTDAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC
>NZ_CP027221.1|WP_000388150.1|4147557_4149855_+|xanthine-dehydrogenase-molybdenum-binding-subunit-XdhA
MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVRSPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPFATAGHAWTLDENKRDTADRALLTRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWQELPVITTPEAALAEDAAPIHNGGNLLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSSTQIPHIVRRVVGQALDIPWSCVRVIKPFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKVSLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGNKVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEIRLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVACFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVSDVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNLTLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVDLTVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGVVRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMATGVAINTLPLTPKRLYEEFHLAGLI
>NZ_CP027221.1|WP_000459182.1|4149865_4150744_+|xanthine-dehydrogenase-FAD-binding-subunit-XdhB
MFDFASYHRAATLADAINLLADNPQAKLLAGGTDVLIQLHHHNDRYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQLIEDPITQRHLPALCAAATSIAGPQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSLEHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFGVAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMTKKVISEAVAAAGGKLQ
>NZ_CP027221.1|WP_001016605.1|4150740_4151220_+|xanthine-dehydrogenase-iron-sulfur-binding-subunit-XdhC
MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
>NZ_CP027221.1|WP_000417770.1|4151259_4153038_-|sigma-54-dependent-transcriptional-regulator
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAGTGAFGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISKIFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREALSRHNSKKQVADELGIGIATLYRKIKKYELLNT
>NZ_CP027221.1|WP_001303128.1|4153516_4154704_+|knotted-carbamoyltransferase-YgeW
MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK
>NZ_CP027221.1|WP_000110493.1|4154761_4155958_+|diaminopropionate-ammonia-lyase
MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRPTPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSFEHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIVNVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRIISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEGKHAVAP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP027221_1	1.1\|3999435\|32\|NZ_CP027221\|CRT	3999435-3999466	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	3	0.906
NZ_CP027221_3	3.1\|4142986\|28\|NZ_CP027221\|CRISPRCasFinder	4142986-4143013	28	MN694712	Marine virus AFVG_250M502, complete genome	31102-31129	4	0.857
NZ_CP027221_3	3.1\|4142986\|28\|NZ_CP027221\|CRISPRCasFinder	4142986-4143013	28	MN694478	Marine virus AFVG_250M504, complete genome	5065-5092	4	0.857
NZ_CP027221_3	3.1\|4142986\|28\|NZ_CP027221\|CRISPRCasFinder	4142986-4143013	28	MN694270	Marine virus AFVG_250M505, complete genome	5187-5214	4	0.857
NZ_CP027221_3	3.1\|4142986\|28\|NZ_CP027221\|CRISPRCasFinder	4142986-4143013	28	MN693238	Marine virus AFVG_25M402, complete genome	24599-24626	5	0.821
NZ_CP027221_1	1.2\|3999496\|32\|NZ_CP027221\|CRT,PILER-CR,CRISPRCasFinder	3999496-3999527	32	NZ_CP050442	Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence	41503-41534	6	0.812
NZ_CP027221_1	1.1\|3999435\|32\|NZ_CP027221\|CRT	3999435-3999466	32	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	112768-112799	7	0.781
NZ_CP027221_1	1.1\|3999435\|32\|NZ_CP027221\|CRT	3999435-3999466	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1428097-1428128	8	0.75
NZ_CP027221_2	2.1\|4025469\|32\|NZ_CP027221\|CRISPRCasFinder	4025469-4025500	32	MK814759	Gordonia phage Reyja, complete genome	4467-4498	8	0.75
NZ_CP027221_1	1.1\|3999435\|32\|NZ_CP027221\|CRT	3999435-3999466	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	141278-141309	9	0.719
NZ_CP027221_1	1.3\|3999557\|32\|NZ_CP027221\|CRT,PILER-CR,CRISPRCasFinder	3999557-3999588	32	LT599585	Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid	32377-32408	9	0.719
NZ_CP027221_1	1.4\|3999618\|32\|NZ_CP027221\|CRT,PILER-CR,CRISPRCasFinder	3999618-3999649	32	NC_010553	Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence	292180-292211	9	0.719
NZ_CP027221_1	1.4\|3999618\|32\|NZ_CP027221\|CRT,PILER-CR,CRISPRCasFinder	3999618-3999649	32	NZ_CP020740	[Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence	20747-20778	9	0.719

1. spacer 1.1|3999435|32|NZ_CP027221|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 3, identity: 0.906

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
caagtgatgtccatcatcgcatccagtgcgtc	Protospacer
.*******.*********************.*

2. spacer 3.1|4142986|28|NZ_CP027221|CRISPRCasFinder matches to MN694712 (Marine virus AFVG_250M502, complete genome) position: , mismatch: 4, identity: 0.857

tacacttttt-tagagatgaaaaaggtat	CRISPR spacer
-atagtttttacagagatgaaaaaggtat	Protospacer
 *.* ***** .*****************

3. spacer 3.1|4142986|28|NZ_CP027221|CRISPRCasFinder matches to MN694478 (Marine virus AFVG_250M504, complete genome) position: , mismatch: 4, identity: 0.857

tacacttttt-tagagatgaaaaaggtat	CRISPR spacer
-atagtttttacagagatgaaaaaggtat	Protospacer
 *.* ***** .*****************

4. spacer 3.1|4142986|28|NZ_CP027221|CRISPRCasFinder matches to MN694270 (Marine virus AFVG_250M505, complete genome) position: , mismatch: 4, identity: 0.857

tacacttttt-tagagatgaaaaaggtat	CRISPR spacer
-atagtttttacagagatgaaaaaggtat	Protospacer
 *.* ***** .*****************

5. spacer 3.1|4142986|28|NZ_CP027221|CRISPRCasFinder matches to MN693238 (Marine virus AFVG_25M402, complete genome) position: , mismatch: 5, identity: 0.821

tacacttttttagagatgaaaaaggtat	CRISPR spacer
tagacctttttagagatgaaaaagcaaa	Protospacer
** **.******************  *

6. spacer 1.2|3999496|32|NZ_CP027221|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP050442 (Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

aaaaccaaacttctccataaattccatagccg	CRISPR spacer
attactaaacttctgcataaattccataggag	Protospacer
*  **.******** **************  *

7. spacer 1.1|3999435|32|NZ_CP027221|CRT matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 7, identity: 0.781

taagtgat-atccatcatcgcatccagtgcgcc	CRISPR spacer
-ggttgatcgtccttcatcgcagccagtgcgcc	Protospacer
 .. **** .*** ******** **********

8. spacer 1.1|3999435|32|NZ_CP027221|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

taagtg---atatccatcatcgcatccagtgcgcc	CRISPR spacer
---gtgcgcccctccatcaccgcttccagtgcgcc	Protospacer
   ***    . *******.*** ***********

9. spacer 2.1|4025469|32|NZ_CP027221|CRISPRCasFinder matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 8, identity: 0.75

-gacagaacggcctcagtagtctcgtcaggctc	CRISPR spacer
ccaccg-ctggccccagtagcctcgtcaggctt	Protospacer
  ** *  .****.******.***********.

10. spacer 1.1|3999435|32|NZ_CP027221|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.719

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
ctcatcgcatccatcatcggttccagtgcgcc	Protospacer
.  .* ..***********  ***********

11. spacer 1.3|3999557|32|NZ_CP027221|CRT,PILER-CR,CRISPRCasFinder matches to LT599585 (Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid) position: , mismatch: 9, identity: 0.719

gagagtgctgacaggtgtctcgattacctgat	CRISPR spacer
ggctttgctggcaggtctctcgattaccttgg	Protospacer
*.   *****.***** ************ .

12. spacer 1.4|3999618|32|NZ_CP027221|CRT,PILER-CR,CRISPRCasFinder matches to NC_010553 (Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence) position: , mismatch: 9, identity: 0.719

gaacgcaatatcacggcgttctgcggcctcgg	CRISPR spacer
atcggcaatatcacggcgtttttcggcgccgc	Protospacer
.   ****************.* **** .**

13. spacer 1.4|3999618|32|NZ_CP027221|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP020740 ([Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence) position: , mismatch: 9, identity: 0.719

gaacgcaatatcacggcgttctgcggcctcgg	CRISPR spacer
accggcaacatcacggcgttcttcggcgccgc	Protospacer
.   ****.************* **** .**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

214025 : 260250

Stx2-converting_phage(34.09%)

tail,transposase,tRNA,head,terminase,capsid,holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000956557.1\|214025_214559_+	hypothetical protein	K7PKJ4	Enterobacteria_phage	1.1e-99	100.0
WP_001093918.1\|214976_215258_-	hypothetical protein	K7PGU0	Enterobacteria_phage	8.7e-45	98.9
WP_001061339.1\|215294_215867_-	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	6.7e-108	97.9
WP_001094871.1\|215866_216601_-	DUF551 domain-containing protein	S5MC19	Escherichia_phage	1.4e-139	98.8
WP_001014294.1\|216603_216795_-	hypothetical protein	G9L660	Escherichia_phage	9.5e-27	100.0
WP_000829414.1\|216847_217264_-	hypothetical protein	A0A076GCN9	Escherichia_phage	1.4e-30	69.9
WP_085948178.1\|217772_218985_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_001242740.1\|219193_219544_-	hypothetical protein	A0A0P0ZBF8	Stx2-converting_phage	1.6e-56	94.8
WP_000008211.1\|219534_220071_-	5'-deoxynucleotidase	U5P0T3	Shigella_phage	3.1e-99	98.3
WP_000081302.1\|220198_221023_-	YfdQ family protein	Q8SBF9	Shigella_phage	1.0e-149	99.6
WP_000135680.1\|221088_221451_-	hypothetical protein	Q8SBF8	Shigella_phage	8.6e-61	100.0
WP_001345148.1\|222154_222847_-	helix-turn-helix transcriptional regulator	S5FUZ3	Shigella_phage	8.3e-121	96.1
WP_001191679.1\|222944_223205_+	helix-turn-helix transcriptional regulator	K7PJQ8	Enterobacteria_phage	7.8e-40	97.7
WP_000515862.1\|223197_223749_+	hypothetical protein	Q8SBF4	Shigella_phage	9.9e-101	99.5
WP_001047110.1\|225261_226014_+	antitermination protein	K7PGU5	Enterobacteria_phage	5.3e-137	99.2
WP_001339373.1\|226323_226476_+	restriction endonuclease subunit M	A0A2R2Z327	Escherichia_phage	3.4e-19	98.0
WP_000143076.1\|227293_229144_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.9
WP_000411802.1\|229592_229799_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000075132.1\|229798_230296_+	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_001208681.1\|230512_230698_+	membrane protein	A0A1U9AJA4	Stx1_converting_phage	2.9e-20	78.7
WP_001303878.1\|231225_231540_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001377217.1\|231793_232324_+	HNH endonuclease	H6WZK7	Escherichia_phage	1.2e-90	93.2
WP_000958398.1\|232439_233003_+\|terminase	terminase small subunit	B6DZ97	Enterobacteria_phage	7.3e-83	94.1
WP_009453642.1\|232999_234661_+\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	98.7
WP_000173088.1\|234724_236662_+\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	98.4
WP_001063096.1\|236706_236928_+	hypothetical protein	H6WZL1	Escherichia_phage	3.4e-36	100.0
WP_000125988.1\|239291_239618_+\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_001007905.1\|239627_239978_+\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000573374.1\|239974_240421_+	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_000133388.1\|240417_240762_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_001275461.1\|240828_241545_+\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.1e-127	98.3
WP_001030043.1\|241550_241925_+\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	1.7e-64	99.2
WP_001453698.1\|242020_242230_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_000212952.1\|242281_245524_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	93.2
WP_000807964.1\|245516_245858_+\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
WP_001152209.1\|245857_246556_+\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	3.1e-131	98.3
WP_000194763.1\|246566_247310_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.4e-150	99.2
WP_126303346.1\|247255_247888_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	1.2e-97	90.5
WP_000514845.1\|248123_251600_+	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	96.1
WP_001216290.1\|251668_252292_+	Ail/Lom family outer membrane beta-barrel protein	A0A1U8QHD6	Enterobacteria_phage	1.1e-68	60.4
WP_000279033.1\|252356_253670_+\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	3.3e-78	99.1
WP_001023417.1\|253671_253941_+\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	2.4e-44	98.9
WP_000442132.1\|254101_254524_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	5.7e-72	97.0
WP_001345294.1\|254653_255712_-	T3SS effector EspW	NA	NA	NA	NA
WP_001117798.1\|255790_256441_-	T3SS effector NleG family protein	B6DZZ5	Stx2-converting_phage	2.8e-25	37.2
WP_001132154.1\|256623_257214_+	T3SS effector guanine nucleotide exchange factor EspM2	NA	NA	NA	NA
WP_001217542.1\|257715_257964_-	DinI-like family protein	A5LH55	Enterobacteria_phage	3.1e-38	98.8
WP_000543817.1\|259212_260250_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA

DBSCAN-SWA_2

374886 : 437123

Vibrio_phage(14.29%)

tRNA,integrase,protease,transposase

attL 416625:416654|attR 440812:440841

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000811566.1\|374886_375162_+\|protease	protease activator YjfN	NA	NA	NA	NA
WP_001299838.1\|375278_376904_-	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_000943991.1\|376987_378151_-	glutathionylspermidine synthase family protein	B2ZXR7	Ralstonia_phage	4.9e-81	43.8
WP_000101670.1\|378153_378792_-	DUF1190 domain-containing protein	NA	NA	NA	NA
WP_000547760.1\|378801_379200_-	DUF350 domain-containing protein	NA	NA	NA	NA
WP_000012546.1\|379217_379877_-	YjfK family protein	NA	NA	NA	NA
WP_000511955.1\|379927_380626_-	PspA/IM30 family protein	NA	NA	NA	NA
WP_000220137.1\|380644_381046_-	DUF2170 family protein	NA	NA	NA	NA
WP_001293281.1\|381172_381904_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000076318.1\|382083_384444_-	ribonuclease R	Q0GXV6	Lactococcus_phage	6.2e-67	33.1
WP_001177639.1\|384482_384908_-	nitric oxide-sensing transcriptional repressor NsrR	NA	NA	NA	NA
WP_000527955.1\|385112_386411_-	adenylosuccinate synthase	W5S5V7	Pithovirus	2.2e-66	35.9
WP_001089295.1\|386514_386712_-	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_001232412.1\|386793_387798_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_000312488.1\|387800_389060_-\|protease	FtsH protease activity modulator HflK	A0A1L2CVV0	Pectobacterium_phage	3.6e-05	25.5
WP_000460360.1\|389145_390426_-	GTPase HflX	NA	NA	NA	NA
WP_001051883.1\|390502_390811_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_001280349.1\|390896_391847_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_001122520.1\|391839_393687_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	5.8e-60	41.3
WP_000990321.1\|393696_395034_-	N-acetylmuramoyl-L-alanine amidase AmiB	A0A067ZJB6	Vibrio_phage	8.8e-18	31.0
WP_000981977.1\|395052_395514_-\|tRNA	tRNA (N6-adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase TsaE	NA	NA	NA	NA
WP_106898629.1\|395485_397033_-	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_001294195.1\|397031_398171_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_010723271.1\|398153_398207_-	hypothetical protein	NA	NA	NA	NA
WP_001295188.1\|399070_399616_-	oligoribonuclease	Q8B5Y0	Diachasmimorpha_longicaudata_entomopoxvirus	2.2e-28	40.4
WP_000041970.1\|399710_400763_+	small ribosomal subunit biogenesis GTPase RsgA	NA	NA	NA	NA
WP_000934920.1\|400859_401828_+	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_001236850.1\|401849_405173_+	miniconductance mechanosensitive channel MscM	NA	NA	NA	NA
WP_001276180.1\|405201_405516_-	YjeO family protein	NA	NA	NA	NA
WP_000342867.1\|405512_405827_-	hypothetical protein	NA	NA	NA	NA
WP_001346081.1\|405878_407381_-	glutamate/gamma-aminobutyrate family transporter YjeM	NA	NA	NA	NA
WP_000004771.1\|407599_408577_-	elongation factor P--(R)-beta-lysine ligase	A0A2K9KZX5	Tupanvirus	6.8e-28	28.2
WP_001192991.1\|408901_410710_+	fumarate reductase (quinol) flavoprotein subunit	NA	NA	NA	NA
WP_000829498.1\|410702_411437_+	succinate dehydrogenase/fumarate reductase iron-sulfur subunit	NA	NA	NA	NA
WP_000208757.1\|411447_411843_+	fumarate reductase subunit FrdC	NA	NA	NA	NA
WP_001299198.1\|411853_412213_+	fumarate reductase subunit FrdD	NA	NA	NA	NA
WP_001299193.1\|412275_413409_+	BlaEC family class C beta-lactamase	NA	NA	NA	NA
WP_001238378.1\|413497_414031_+	lipocalin family protein	A0A1W6JNX6	Morganella_phage	2.7e-47	55.0
WP_000118482.1\|414027_414345_-	quaternary ammonium compound efflux SMR transporter SugE	NA	NA	NA	NA
WP_000239596.1\|414526_414673_-	lipoprotein toxin entericidin B	NA	NA	NA	NA
WP_000977757.1\|414783_414909_-	lipoprotein antitoxin entericidin A	NA	NA	NA	NA
WP_000257278.1\|414960_415527_-	elongation factor P	NA	NA	NA	NA
WP_000940530.1\|415568_416597_+	EF-P beta-lysylation protein EpmB	NA	NA	NA	NA
416625:416654	attL	NA	NA	NA	NA
WP_001008073.1\|416986_417856_+	hypothetical protein	NA	NA	NA	NA
WP_000558209.1\|418059_418413_-	DUF4156 domain-containing protein	NA	NA	NA	NA
WP_000729116.1\|418550_420206_-	chaperonin GroEL	A0A2I7SAK5	Vibrio_phage	5.3e-190	68.9
WP_001026276.1\|420249_420543_-	co-chaperone GroES	K4F9I2	Cronobacter_phage	9.2e-13	45.4
WP_000015837.1\|420818_422075_+	L-methionine/branched-chain amino acid transporter	NA	NA	NA	NA
WP_001267448.1\|422090_422567_-	membrane protein FxsA	NA	NA	NA	NA
WP_000069437.1\|422903_424340_+	aspartate ammonia-lyase	NA	NA	NA	NA
WP_000961959.1\|424457_425759_+	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_000883400.1\|425874_426213_+	divalent cation tolerance protein CutA	NA	NA	NA	NA
WP_000068905.1\|426188_427886_+	protein-disulfide reductase DsbD	NA	NA	NA	NA
WP_001188520.1\|427922_428498_+	transcriptional regulator	NA	NA	NA	NA
WP_001218841.1\|428877_430143_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	2.7e-77	38.3
WP_000631719.1\|431804_432152_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	1.0e-42	72.0
WP_000603950.1\|434473_435022_-	Ail/Lom family outer membrane beta-barrel protein	Q9LA63	Enterobacterial_phage	1.3e-15	32.4
WP_001340019.1\|435944_436148_+\|transposase	transposase	NA	NA	NA	NA
WP_159026288.1\|436079_436409_-	hypothetical protein	NA	NA	NA	NA
WP_159026289.1\|436472_437123_+\|transposase	transposase	NA	NA	NA	NA
440812:440841	attR	NA	NA	NA	NA

DBSCAN-SWA_3

491024 : 563209

Escherichia_phage(38.46%)

tRNA,integrase,protease,transposase

attL 494424:494444|attR 539086:539106

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000416419.1\|491024_493880_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	3.0e-140	36.6
WP_001188289.1\|493879_494362_-	DNA polymerase III subunit chi	NA	NA	NA	NA
494424:494444	attL	NA	NA	NA	NA
WP_000397144.1\|494455_495967_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	6.0e-47	38.0
WP_000584114.1\|496233_497334_+	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_001295681.1\|497333_498416_+	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_001345322.1\|500165_501185_-	NADPH-dependent aldehyde reductase Ahr	A0A0G2Y405	Acanthamoeba_polyphaga_mimivirus	3.5e-43	30.1
WP_001219053.1\|501665_502376_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	1.3e-41	42.7
WP_000357928.1\|502379_503042_+	hypothetical protein	NA	NA	NA	NA
WP_000361917.1\|503555_504473_-	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_000157137.1\|504465_505239_-	hypothetical protein	NA	NA	NA	NA
WP_000766442.1\|505818_507168_-	phospholipase	NA	NA	NA	NA
WP_001193075.1\|507286_509371_-\|protease	protease Lon-related BREX system protein BrxL	NA	NA	NA	NA
WP_001180889.1\|509381_511979_-	BREX-1 system phosphatase PglZ type A	NA	NA	NA	NA
WP_001095581.1\|512155_515830_-	BREX-1 system adenine-specific DNA-methyltransferase PglX	NA	NA	NA	NA
WP_085948178.1\|516047_517260_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000566901.1\|520841_521444_-	DUF1788 domain-containing protein	NA	NA	NA	NA
WP_023982161.1\|521440_522043_-	DUF1819 family protein	NA	NA	NA	NA
WP_000168567.1\|523446_524319_-	HNH endonuclease	NA	NA	NA	NA
WP_001338066.1\|524400_524523_+	hypothetical protein	NA	NA	NA	NA
WP_000991446.1\|524530_525511_-	9-O-acetyl-N-acetylneuraminic acid deacetylase	Q08JA2	Stx2-converting_phage	9.4e-102	55.9
WP_001044128.1\|525575_526682_-	N-acetylneuraminate epimerase	NA	NA	NA	NA
WP_001295734.1\|526701_527418_-	N-acetylneuraminic acid outer membrane channel NanC	NA	NA	NA	NA
WP_000790592.1\|528873_529476_+	type 1 fimbria regulatory protein FimB	A0A2L1IV36	Escherichia_phage	1.5e-54	51.8
WP_000044711.1\|529953_530550_+	type 1 fimbria regulatory protein FimE	A0A2L1IV36	Escherichia_phage	3.9e-50	53.4
WP_000695543.1\|531030_531579_+	metal ABC transporter substrate-binding lipoprotein/fibrin-binding adhesin FimA	NA	NA	NA	NA
WP_000824107.1\|531643_532183_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_000066557.1\|532219_532945_+	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_085948178.1\|535571_536785_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_001244827.1\|536971_537502_+	type 1 fimbria minor subunit FimF	NA	NA	NA	NA
WP_000870592.1\|537514_538018_+	type 1 fimbria minor subunit FimG	NA	NA	NA	NA
WP_000832227.1\|538037_538940_+	type 1 fimbria D-mannose specific adhesin FimH	NA	NA	NA	NA
WP_000558253.1\|539189_540533_-	gluconate permease GntP	NA	NA	NA	NA
539086:539106	attR	NA	NA	NA	NA
WP_000438591.1\|540872_542057_+	mannonate dehydratase	NA	NA	NA	NA
WP_000208201.1\|542137_543598_+	fructuronate reductase	H8ZJP8	Ostreococcus_tauri_virus	7.3e-50	32.2
WP_000833679.1\|543812_544586_+	Uxu operon transcriptional regulator	NA	NA	NA	NA
WP_000062565.1\|544726_545557_-	DUF2686 family protein	NA	NA	NA	NA
WP_120795393.1\|546148_546232_+	iraD leader peptide	NA	NA	NA	NA
WP_000986213.1\|546228_546621_+	anti-adapter protein IraD	NA	NA	NA	NA
WP_000340733.1\|546613_547525_-	hypochlorite stress DNA-binding transcriptional regulator HypT	NA	NA	NA	NA
WP_000568417.1\|547589_548762_-	beta-aspartyl-peptidase	NA	NA	NA	NA
WP_000211972.1\|548774_549236_-	membrane protein	NA	NA	NA	NA
WP_001295597.1\|549232_549916_-	nucleoside recognition pore and gate family inner membrane transporter	NA	NA	NA	NA
WP_001151854.1\|550165_550720_+	RNA 2'-phosphotransferase	A0A2R2ZGT8	Clostridioides_phage	2.7e-37	45.6
WP_001141203.1\|550732_551911_-	MFS transporter	NA	NA	NA	NA
WP_001298932.1\|551978_552839_-	YjiK family protein	NA	NA	NA	NA
WP_000657679.1\|552903_553161_-	DUF3343 domain-containing protein	NA	NA	NA	NA
WP_000222502.1\|553157_553925_-	hypothetical protein	NA	NA	NA	NA
WP_001298930.1\|553934_555086_-	2-hydroxyacyl-CoA dehydratase subunit D	NA	NA	NA	NA
WP_001038277.1\|555201_556482_-	DUF445 domain-containing protein	NA	NA	NA	NA
WP_001137002.1\|556522_557755_-	multidrug efflux MFS transporter MdtM	NA	NA	NA	NA
WP_000181112.1\|558221_559178_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	1.7e-60	51.2
WP_000199283.1\|559422_560835_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_000394274.1\|561011_561176_+	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_085948178.1\|561996_563209_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7

DBSCAN-SWA_4

955202 : 966089

Enterobacteria_phage(22.22%)

integrase,transposase

attL 948794:948807|attR 963403:963416

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
948794:948807	attL	NA	NA	NA	NA
WP_000749863.1\|955202_956258_-	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	9.1e-119	61.1
WP_001285288.1\|956545_957649_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000893251.1\|957660_958914_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.7e-95	47.0
WP_000772642.1\|959269_960484_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	7.5e-133	56.5
WP_000251023.1\|960626_961508_+	hypothetical protein	NA	NA	NA	NA
WP_000083330.1\|961705_961903_+	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.7e-07	48.1
WP_001035842.1\|961902_962334_+	hypothetical protein	A0A1W6JPH9	Morganella_phage	5.1e-28	49.0
WP_001019379.1\|962346_963180_+	hypothetical protein	G9L6G1	Escherichia_phage	5.3e-21	47.5
WP_085948178.1\|963313_964526_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
963403:963416	attR	NA	NA	NA	NA
WP_000942525.1\|965018_966089_+	DNA cytosine methyltransferase	A0A1B1IRZ3	uncultured_Mediterranean_phage	2.6e-20	29.6

DBSCAN-SWA_5

1179898 : 1287825

Escherichia_phage(34.48%)

tRNA,transposase,head,tail,capsid,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000186631.1\|1179898_1180378_-\|tRNA	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK	NA	NA	NA	NA
WP_000365177.1\|1180581_1181376_-	hypothetical protein	NA	NA	NA	NA
WP_001342071.1\|1181513_1181855_+	HigA family addiction module antidote protein	A0A222YWD7	Escherichia_phage	2.1e-40	74.5
WP_000078269.1\|1181968_1184473_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	3.8e-115	38.4
WP_000883048.1\|1184734_1185667_+	glutaminase A	NA	NA	NA	NA
WP_000982172.1\|1185669_1186962_+	amino acid permease	NA	NA	NA	NA
WP_001026747.1\|1187086_1187494_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_000970323.1\|1187494_1187953_-	NfeD family protein	NA	NA	NA	NA
WP_000904502.1\|1187949_1188867_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_001157532.1\|1189012_1189690_+	iron ABC transporter ATP-binding protein FetA	G3M9Y6	Bacillus_virus	3.1e-27	33.8
WP_001345010.1\|1189676_1190459_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_001295322.1\|1190521_1191376_-	chaperedoxin	NA	NA	NA	NA
WP_000148941.1\|1191436_1192246_-	NADP(+)-dependent aldehyde reductase	NA	NA	NA	NA
WP_001295836.1\|1192235_1192859_-\|protease	multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1	NA	NA	NA	NA
WP_001110573.1\|1192829_1193516_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.9e-33	35.6
WP_000561841.1\|1193512_1195927_+	ABC transporter permease	NA	NA	NA	NA
WP_001320180.1\|1200548_1200809_+	hypothetical protein	NA	NA	NA	NA
WP_001158001.1\|1202040_1203135_-\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
WP_000460145.1\|1203203_1204130_-	HTH-type transcriptional activator AllS	NA	NA	NA	NA
WP_000776388.1\|1204359_1204842_+	ureidoglycolate lyase	NA	NA	NA	NA
WP_000141275.1\|1204919_1205735_+	HTH-type transcriptional repressor AllR	NA	NA	NA	NA
WP_001342079.1\|1205824_1207606_+	glyoxylate carboligase	E4WLQ6	Ostreococcus_tauri_virus	7.8e-38	27.0
WP_000943558.1\|1207618_1208395_+	hydroxypyruvate isomerase	NA	NA	NA	NA
WP_000765839.1\|1208494_1209373_+	2-hydroxy-3-oxopropionate reductase	NA	NA	NA	NA
WP_000401100.1\|1209541_1210996_+	putative allantoin permease	NA	NA	NA	NA
WP_000006887.1\|1211055_1212417_+	allantoinase AllB	NA	NA	NA	NA
WP_001298987.1\|1212473_1213775_+	uracil/xanthine transporter	NA	NA	NA	NA
WP_001315307.1\|1213796_1214942_+	glycerate 3-kinase	W6LM47	Streptococcus_phage	1.1e-48	41.9
WP_000540946.1\|1215070_1215856_-	(S)-ureidoglycine aminohydrolase	NA	NA	NA	NA
WP_001301144.1\|1215866_1217102_-	allantoate deiminase	NA	NA	NA	NA
WP_000703909.1\|1217123_1218173_-	ureidoglycolate dehydrogenase	NA	NA	NA	NA
WP_000580836.1\|1218489_1220157_+	acyl-CoA synthetase FdrA	NA	NA	NA	NA
WP_000495365.1\|1220166_1221426_+	DUF1116 domain-containing protein	NA	NA	NA	NA
WP_000152513.1\|1221436_1222252_+	DUF2877 domain-containing protein	NA	NA	NA	NA
WP_000855355.1\|1222248_1223142_+	carbamate kinase	NA	NA	NA	NA
WP_000815554.1\|1223278_1224346_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_001295318.1\|1224342_1224852_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_000212252.1\|1224969_1225692_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_000256002.1\|1225694_1226189_-	peptidylprolyl isomerase B	NA	NA	NA	NA
WP_000912342.1\|1226362_1227748_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.0e-45	34.8
WP_001143540.1\|1227783_1228305_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_000190288.1\|1228412_1228625_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_000729154.1\|1228626_1229493_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
WP_000776555.1\|1229973_1230516_+	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
WP_000988363.1\|1230735_1231428_+	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_001345007.1\|1231458_1234068_+	fimbrial biogenesis usher protein	NA	NA	NA	NA
WP_001255226.1\|1235119_1235635_+	fimbria assembly protein	NA	NA	NA	NA
WP_000805428.1\|1235637_1236270_-	fimbria biosynthesis transcriptional regulator FimZ	NA	NA	NA	NA
WP_001345004.1\|1237480_1237813_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.0e-55	99.1
WP_000063245.1\|1237868_1238894_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	3.1e-188	97.4
WP_000158868.1\|1238935_1239331_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	5.7e-58	95.5
WP_000752958.1\|1239342_1239642_+\|head,tail	head-tail joining protein	A0A2R9YJJ5	Escherichia_phage	8.4e-46	98.9
WP_085947772.1\|1239662_1240875_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	8.3e-100	57.1
WP_000985133.1\|1240968_1241547_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.0e-79	98.4
WP_000683103.1\|1241543_1241939_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.4e-69	98.5
WP_001342267.1\|1241946_1242687_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	1.0e-129	98.0
WP_000479169.1\|1242702_1243125_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.1e-70	96.4
WP_000459457.1\|1243106_1243541_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_106898639.1\|1243533_1245714_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	90.6
WP_085948178.1\|1245719_1246932_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_153244794.1\|1246898_1247045_+	hypothetical protein	A0A0N7BTS3	Escherichia_phage	5.4e-06	96.0
WP_000239881.1\|1247002_1247671_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000937502.1\|1247727_1248033_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.8e-12	76.5
WP_001226384.1\|1248216_1249701_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001201824.1\|1249887_1250841_-\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001177454.1\|1251353_1252115_-	DNA-binding transcriptional regulator EnvY	NA	NA	NA	NA
WP_001224569.1\|1252297_1253188_-	DUF4434 family protein	NA	NA	NA	NA
WP_001345000.1\|1253188_1256161_-	bacteriophage adsorption protein NfrA	NA	NA	NA	NA
WP_000383942.1\|1256147_1258385_-	phage adsorption protein NrfB	NA	NA	NA	NA
WP_000420935.1\|1258653_1259790_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_001344803.1\|1259916_1260240_-	sugar-binding protein	NA	NA	NA	NA
WP_000333355.1\|1260283_1260721_-	hypothetical protein	NA	NA	NA	NA
WP_000092528.1\|1261025_1261391_-	hypothetical protein	NA	NA	NA	NA
WP_001289036.1\|1261392_1266192_-	type IV secretion protein Rhs	A0A2H4JHK7	uncultured_Caudovirales_phage	1.9e-17	38.9
WP_001160811.1\|1266211_1266673_-	DcrB-related protein	NA	NA	NA	NA
WP_000103161.1\|1266700_1268602_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	3.9e-27	25.7
WP_000253805.1\|1269338_1270787_-	Cu(+)/Ag(+) sensor histidine kinase CusS	A0A1V0SGX0	Hokovirus	3.9e-11	26.1
WP_000770957.1\|1270776_1271460_-	copper response regulator transcription factor CusR	W8CYM9	Bacillus_phage	3.9e-30	34.7
WP_000074251.1\|1271616_1272990_+	Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC	NA	NA	NA	NA
WP_000709879.1\|1273147_1273480_+	Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone CusF	NA	NA	NA	NA
WP_000573931.1\|1274731_1277875_+	Cu(+)/Ag(+) efflux RND transporter permease subunit CusA	S5VTK5	Leptospira_phage	3.2e-58	22.1
WP_000786320.1\|1277976_1279353_+	phenylalanine transporter	NA	NA	NA	NA
WP_001153146.1\|1279420_1280668_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_000351464.1\|1280775_1281429_-	oxygen-insensitive NAD(P)H nitroreductase	NA	NA	NA	NA
WP_000360951.1\|1281522_1281891_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_000682517.1\|1281955_1282204_-	DUF1158 domain-containing protein	NA	NA	NA	NA
WP_001130618.1\|1282269_1283388_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_000956455.1\|1283829_1283982_+	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_000956465.1\|1284332_1284485_+	type I toxin-antitoxin system Hok family toxin	NA	NA	NA	NA
WP_001369229.1\|1284606_1285227_-	enterobactin synthase subunit EntD	NA	NA	NA	NA
WP_106898640.1\|1285401_1286646_-	TonB-dependent siderophore receptor	A0A0N7BTS3	Escherichia_phage	3.6e-05	96.0
WP_085948178.1\|1286611_1287825_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7

DBSCAN-SWA_6

1480637 : 1503827

Enterobacteria_phage(56.52%)

integrase,transposase,head,tail,capsid

attL 1475230:1475246|attR 1496140:1496156

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1475230:1475246	attL	NA	NA	NA	NA
WP_000263438.1\|1480637_1481714_-\|integrase	tyrosine-type recombinase/integrase	K7P6P6	Enterobacteria_phage	1.8e-199	99.4
WP_000638251.1\|1481727_1482138_-	lysozyme	A0A0N7KZA0	Stx2-converting_phage	1.1e-64	99.2
WP_085948178.1\|1482121_1483335_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_001254039.1\|1483969_1485475_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.6e-100	54.0
WP_000256792.1\|1485511_1485859_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.0e-22	58.1
WP_000522630.1\|1485916_1486945_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.3e-114	61.3
WP_000201528.1\|1486996_1487371_+	hypothetical protein	NA	NA	NA	NA
WP_001204544.1\|1487363_1487717_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	2.5e-41	69.2
WP_000975037.1\|1487731_1488307_+\|tail	tail protein	A0A2R9YJK4	Escherichia_phage	7.5e-51	58.7
WP_000683071.1\|1488303_1488699_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	4.2e-61	87.0
WP_001143011.1\|1488706_1489459_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.9e-132	97.2
WP_000479083.1\|1489472_1489904_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-41	67.4
WP_000533403.1\|1489930_1490344_+\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_106888365.1\|1490324_1492904_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	80.4
WP_000847298.1\|1492900_1493230_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_000194798.1\|1493937_1494681_+\|tail	phage tail protein	Q9EYE4	Enterobacteria_phage	3.7e-151	100.0
WP_159026291.1\|1494626_1495256_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	6.6e-109	98.6
WP_000514984.1\|1495496_1498973_+	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	89.5
1496140:1496156	attR	NA	NA	NA	NA
WP_001230465.1\|1499040_1499640_+	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	1.8e-108	98.0
WP_000268900.1\|1499704_1501018_+\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	9.7e-78	98.9
WP_001023459.1\|1501019_1501289_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	4.6e-43	96.6
WP_000950982.1\|1501394_1502276_+	hypothetical protein	A5LH48	Enterobacteria_phage	3.9e-147	90.4
WP_106898642.1\|1502492_1503332_+	type III secretion system effector Cif	A5LH49	Enterobacteria_phage	2.5e-151	98.2
WP_021351651.1\|1503455_1503827_-	hypothetical protein	K7PH54	Enterobacteria_phage	1.1e-58	95.1

DBSCAN-SWA_7

1724940 : 1771017

Escherichia_phage(34.62%)

transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000156528.1\|1724940_1726701_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000877161.1\|1726886_1727339_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_000750416.1\|1727414_1728455_-	porin OmpA	NA	NA	NA	NA
WP_000288710.1\|1728811_1729321_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_001444487.1\|1729593_1730169_+	CRP-S regulon transcriptional coactivator Sxy	NA	NA	NA	NA
WP_000875023.1\|1730131_1732294_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_001261235.1\|1732303_1732750_-	YccF domain-containing protein	NA	NA	NA	NA
WP_001297106.1\|1732872_1734927_+	DNA helicase IV	A7KV33	Bacillus_phage	7.7e-21	27.9
WP_000424181.1\|1734958_1735417_-	methylglyoxal synthase	NA	NA	NA	NA
WP_000847791.1\|1735512_1736175_-	DUF2057 family protein	NA	NA	NA	NA
WP_000665217.1\|1736347_1736761_+	CoA-binding protein	NA	NA	NA	NA
WP_001295356.1\|1736805_1737123_-	heat shock protein HspQ	NA	NA	NA	NA
WP_000116302.1\|1737180_1738371_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_000048244.1\|1738465_1738744_+	acylphosphatase	NA	NA	NA	NA
WP_000904442.1\|1738740_1739070_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_000375138.1\|1739160_1739820_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	5.2e-48	54.9
WP_000273151.1\|1741220_1741463_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_001090200.1\|1744090_1744282_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449192.1\|1744278_1744467_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_000394557.1\|1744998_1745373_-	hypothetical protein	NA	NA	NA	NA
WP_000379580.1\|1745384_1745537_-	DUF1391 family protein	M4QQ57	Salicola_phage	3.9e-07	53.2
WP_000103686.1\|1745808_1746525_-	helix-turn-helix domain-containing protein	H9C160	Pectobacterium_phage	3.8e-52	42.0
WP_000471549.1\|1746574_1746790_+	transcriptional regulator	NA	NA	NA	NA
WP_000693949.1\|1746786_1747212_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001262389.1\|1747283_1748354_+	hypothetical protein	A0A088CD36	Shigella_phage	3.2e-63	65.2
WP_001151153.1\|1748394_1748817_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.1e-64	92.1
WP_001266135.1\|1748813_1749110_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	7.5e-47	93.7
WP_001209481.1\|1749106_1749568_+	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	3.4e-38	92.9
WP_000403777.1\|1749545_1749902_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	3.0e-58	98.3
WP_000935420.1\|1749952_1750165_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.8e-33	94.3
WP_042350895.1\|1750250_1750415_+	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	2.0e-17	90.7
WP_000224233.1\|1750416_1750680_+	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
WP_000207986.1\|1750690_1751560_+	DUF551 domain-containing protein	A0A1U9AJ59	Stx1_converting_phage	5.2e-120	76.8
WP_001278454.1\|1751675_1751780_+	hypothetical protein	NA	NA	NA	NA
WP_000902696.1\|1751968_1752181_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.2e-25	91.4
WP_032280206.1\|1752348_1752609_+	hypothetical protein	NA	NA	NA	NA
WP_001265133.1\|1752628_1753678_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	3.4e-110	54.9
WP_001217436.1\|1753690_1754062_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_000090265.1\|1754051_1754423_+	antitermination protein	Q777W5	Enterobacteria_phage	1.0e-53	84.0
WP_000265267.1\|1754574_1755393_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000917737.1\|1755679_1755877_+	hypothetical protein	S5MQK8	Escherichia_phage	2.6e-27	96.9
WP_000261909.1\|1756014_1756728_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000874357.1\|1757495_1759346_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	95.9
WP_000411814.1\|1759793_1760000_+\|holin	holin	Q6H9V8	Enterobacteria_phage	5.3e-31	98.5
WP_000138558.1\|1760255_1760528_-	hypothetical protein	NA	NA	NA	NA
WP_001003118.1\|1760687_1761221_+	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.1e-99	94.4
WP_000675929.1\|1761441_1761555_+	hypothetical protein	A0A2L1IV24	Escherichia_phage	5.6e-11	97.3
WP_012816791.1\|1761776_1761962_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_001303878.1\|1762488_1762803_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001303940.1\|1762884_1763109_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	1.7e-19	90.6
WP_085948178.1\|1763158_1764372_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_012817858.1\|1764458_1765352_-	Tir-cytoskeleton coupling protein TccP2	NA	NA	NA	NA
WP_001443410.1\|1765797_1766181_-	hypothetical protein	Q6H9S1	Enterobacteria_phage	4.4e-55	84.3
WP_001058323.1\|1766798_1767917_+	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_000107384.1\|1767913_1769707_+	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_001186421.1\|1769725_1770433_+	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_000003671.1\|1770429_1771017_+\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA

DBSCAN-SWA_8

1993364 : 2061147

Stx2-converting_phage(35.85%)

integrase,tail,transposase,tRNA,head,terminase,capsid,holin

attL 1988458:1988472|attR 1994939:1994953

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1988458:1988472	attL	NA	NA	NA	NA
WP_000074981.1\|1993364_1994483_-\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	2.9e-83	43.9
WP_000003742.1\|1994451_1994721_-	excisionase	NA	NA	NA	NA
WP_000048442.1\|1994782_1997248_-	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	57.1
1994939:1994953	attR	NA	NA	NA	NA
WP_001090200.1\|1997340_1997532_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449192.1\|1997528_1997717_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_122993436.1\|1998056_1998197_+	hypothetical protein	NA	NA	NA	NA
WP_001171930.1\|1998200_1998419_-	hypothetical protein	NA	NA	NA	NA
WP_001447517.1\|1998459_1998849_-	hypothetical protein	NA	NA	NA	NA
WP_001303511.1\|1999144_1999423_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_001302048.1\|1999424_1999616_-	hypothetical protein	NA	NA	NA	NA
WP_001169687.1\|1999636_2000008_-	hypothetical protein	NA	NA	NA	NA
WP_001444689.1\|2000105_2000408_+	transcriptional regulator	K7PHA1	Enterobacteria_phage	1.5e-05	34.8
WP_000693943.1\|2000404_2000830_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000095671.1\|2000852_2001815_+	DNA-binding protein	U5P0A0	Shigella_phage	2.1e-69	51.2
WP_001151120.1\|2001855_2002278_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.3e-63	89.9
WP_000004322.1\|2002274_2002529_+	hypothetical protein	A0A0U2RK51	Escherichia_phage	4.8e-42	94.0
WP_001002672.1\|2002521_2002833_+	hypothetical protein	A0A0U2QV73	Escherichia_phage	1.1e-59	97.1
WP_001204666.1\|2003138_2003717_+	sce7726 family protein	A0A0U2RXY7	Escherichia_phage	2.6e-104	100.0
WP_000156210.1\|2003676_2004774_-	hypothetical protein	A0A0U2S621	Escherichia_phage	1.4e-210	99.5
WP_085948178.1\|2005408_2006622_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_072058819.1\|2006659_2006800_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	2.2e-12	95.0
WP_012817871.1\|2006967_2007240_+	hypothetical protein	I6PCV7	Cronobacter_phage	9.4e-12	49.2
WP_001369253.1\|2007241_2008297_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	2.4e-87	47.8
WP_000140024.1\|2008297_2008663_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	64.3
WP_000640048.1\|2008671_2009202_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	9.3e-72	72.6
WP_000917750.1\|2009443_2009641_+	hypothetical protein	S5MQK8	Escherichia_phage	1.0e-28	98.5
WP_000935544.1\|2009791_2010850_+	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	2.0e-198	94.0
WP_000874287.1\|2011646_2013497_+	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	98.1
WP_000411802.1\|2013944_2014151_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000731236.1\|2014155_2014500_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-58	100.0
WP_000992167.1\|2014550_2015084_+	lysozyme	A0A0N7KZF9	Stx2-converting_phage	7.4e-101	98.9
WP_001056806.1\|2015354_2015924_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539792.1\|2015923_2016070_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_012816791.1\|2016297_2016483_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000095736.1\|2016907_2017135_-	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_000279788.1\|2017176_2017542_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	2.0e-65	99.2
WP_000958415.1\|2017832_2018396_+\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	3.8e-79	100.0
WP_001369319.1\|2018392_2020054_+\|terminase	terminase large subunit	H6WZK9	Escherichia_phage	0.0e+00	98.9
WP_000172984.1\|2020117_2022055_+\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	99.7
WP_001063099.1\|2022099_2022321_+	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000125988.1\|2025009_2025336_+\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_001007905.1\|2025345_2025696_+\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000573391.1\|2025692_2026139_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_000133388.1\|2026135_2026480_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_001275472.1\|2026546_2027263_+\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	5.6e-128	98.7
WP_001030042.1\|2027268_2027643_+\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	6.6e-64	98.4
WP_001453698.1\|2027738_2027948_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_000212932.1\|2027999_2031242_+\|tail	phage tail tape measure protein	A0A0P0ZE78	Stx2-converting_phage	0.0e+00	98.5
WP_000807928.1\|2031234_2031576_+\|tail	phage tail protein	H6WZM2	Escherichia_phage	5.3e-60	95.6
WP_001447444.1\|2031575_2032274_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	4.4e-130	97.4
WP_001302649.1\|2032290_2032611_-	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.0e-49	100.0
WP_001154345.1\|2032718_2032892_+	Arc family DNA-binding protein	A0A0P0ZC65	Stx2-converting_phage	3.4e-23	100.0
WP_000967279.1\|2033939_2034677_+\|tail	phage tail protein	A0A0P0ZDT1	Stx2-converting_phage	1.9e-147	98.8
WP_122996286.1\|2034622_2035255_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	1.0e-104	97.6
WP_000514853.1\|2035491_2038971_+	host specificity protein J	A0A0P0ZDT4	Stx2-converting_phage	0.0e+00	97.4
WP_001230459.1\|2039037_2039637_+	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	8.0e-112	100.0
WP_000268887.1\|2039701_2041024_+\|tail	tail fiber protein	Q687E6	Enterobacteria_phage	2.4e-76	99.1
WP_001023356.1\|2041025_2041295_+\|tail	phage tail protein	A0A2R2Z347	Escherichia_phage	2.4e-44	98.9
WP_115801847.1\|2041401_2041491_+	hypothetical protein	NA	NA	NA	NA
WP_001301673.1\|2041510_2043859_+	type III secretion system effector E3 ubiquitin ligase NleL	NA	NA	NA	NA
WP_000145590.1\|2048018_2048597_+\|transposase	transposase	NA	NA	NA	NA
WP_001301834.1\|2048619_2048745_+	hypothetical protein	Q8HAB2	Salmonella_phage	8.7e-05	58.3
WP_001303921.1\|2048824_2049100_-	hypothetical protein	NA	NA	NA	NA
WP_000938117.1\|2049160_2050522_-	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	4.0e-50	28.9
WP_000799400.1\|2050885_2051749_-	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000531601.1\|2051732_2052869_-	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	9.4e-29	39.8
WP_000359438.1\|2053118_2054348_+	peptidase T	NA	NA	NA	NA
WP_000456506.1\|2054493_2055615_-	cupin domain-containing protein	NA	NA	NA	NA
WP_000735412.1\|2055690_2057151_-	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_001265481.1\|2057150_2057822_-	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000423729.1\|2057989_2059360_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
WP_001297479.1\|2059363_2060005_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_001297484.1\|2060040_2061147_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA

DBSCAN-SWA_9

2162363 : 2219049

Enterobacteria_phage(44.9%)

holin,tail,transposase,terminase,protease,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000268365.1\|2162363_2162912_+	recombinase family protein	G8I4U3	Mycobacterium_phage	2.7e-21	36.1
WP_085948178.1\|2164743_2165956_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000075578.1\|2166020_2166557_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	4.1e-59	71.9
WP_072127369.1\|2166589_2166871_+	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.6e-30	75.8
WP_001444682.1\|2166867_2167164_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	4.4e-47	93.7
WP_001209477.1\|2167160_2167622_+	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	6.9e-39	95.2
WP_000403788.1\|2167599_2167956_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	6.7e-58	97.5
WP_000137950.1\|2168051_2168423_+	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	2.7e-49	78.9
WP_000610381.1\|2168419_2168773_+	DUF551 domain-containing protein	Q9EY98	Enterobacteria_phage	5.5e-36	65.0
WP_000220602.1\|2168978_2169278_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2R2Z2Y1	Escherichia_phage	1.6e-49	96.0
WP_001260976.1\|2169283_2169541_-	type II toxin-antitoxin system ParD family antitoxin	A0A0N7C055	Escherichia_phage	6.6e-31	88.0
WP_001447497.1\|2169676_2169955_+	hypothetical protein	I6PCV7	Cronobacter_phage	6.9e-10	46.9
WP_001344904.1\|2169956_2171006_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.0e-109	54.3
WP_000904137.1\|2171018_2171393_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.4e-34	62.7
WP_000762902.1\|2171389_2172211_+	hypothetical protein	K7P7B9	Enterobacteria_phage	2.8e-83	61.9
WP_000917735.1\|2172437_2172635_+	hypothetical protein	S5MQK8	Escherichia_phage	1.8e-28	98.5
WP_000483498.1\|2172785_2173844_+	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	1.7e-205	98.0
WP_000142980.1\|2174438_2176385_+	DUF1737 domain-containing protein	Q9EYC8	Enterobacteria_phage	0.0e+00	99.1
WP_000143458.1\|2176522_2176702_+	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_001290214.1\|2176742_2176988_+	DUF826 domain-containing protein	A0A088CE63	Shigella_phage	3.2e-19	98.8
WP_001072901.1\|2177065_2177281_+\|holin	holin	A0A2R2Z340	Escherichia_phage	1.2e-33	100.0
WP_001344902.1\|2177284_2177530_+	hypothetical protein	NA	NA	NA	NA
WP_159026290.1\|2177555_2178693_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	8.8e-144	97.0
WP_085948178.1\|2178699_2179912_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_106898646.1\|2179896_2180295_+	hypothetical protein	Q08JA0	Stx2-converting_phage	1.7e-46	79.6
WP_000992150.1\|2180331_2180865_+	lysozyme	B6DZ92	Enterobacteria_phage	2.1e-100	97.2
WP_012578895.1\|2181383_2181569_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	2.7e-18	98.4
WP_000373407.1\|2182044_2182521_+	DUF1441 family protein	Q8VNN8	Enterobacteria_phage	3.3e-84	100.0
WP_001077625.1\|2182517_2184641_+\|terminase	phage terminase large subunit family protein	Q9EYD1	Enterobacteria_phage	0.0e+00	100.0
WP_000102413.1\|2184637_2184850_+	hypothetical protein	Q687G1	Enterobacteria_phage	2.3e-29	98.6
WP_000974564.1\|2184849_2186352_+\|portal	phage portal protein	Q9EYD2	Enterobacteria_phage	4.8e-291	100.0
WP_001114424.1\|2186296_2188321_+\|protease	Clp protease ClpP	S5M7Q8	Escherichia_phage	0.0e+00	99.8
WP_001097065.1\|2188408_2188735_+	DUF2190 family protein	Q9EYD5	Enterobacteria_phage	6.1e-50	100.0
WP_001281350.1\|2188727_2189009_+	DNA breaking-rejoining protein	Q8VNN4	Enterobacteria_phage	3.9e-45	97.8
WP_000974966.1\|2189011_2189635_+	hypothetical protein	Q9EYD6	Enterobacteria_phage	6.6e-101	100.0
WP_000682716.1\|2189647_2190046_+\|tail	tail protein	Q9EYD7	Enterobacteria_phage	5.9e-71	100.0
WP_000235090.1\|2190053_2190806_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	5.8e-136	100.0
WP_000479043.1\|2190819_2191242_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	5.1e-73	100.0
WP_000532073.1\|2191268_2191577_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	1.3e-54	100.0
WP_000918237.1\|2191620_2194266_+\|tail	phage tail tape measure protein	Q9EYE1	Enterobacteria_phage	0.0e+00	99.4
WP_000847298.1\|2194262_2194592_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_001344666.1\|2195299_2196043_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	1.5e-147	98.4
WP_122996286.1\|2195988_2196621_+\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	1.0e-104	97.6
WP_000514851.1\|2196867_2200344_+	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	96.7
WP_001230455.1\|2200411_2201011_+	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	8.8e-111	99.0
WP_000279057.1\|2201075_2202389_+\|tail	tail fiber protein	A0A0P0ZCC1	Stx2-converting_phage	3.7e-77	97.0
WP_000692020.1\|2203794_2204385_+	protein kinase	NA	NA	NA	NA
WP_001079509.1\|2205421_2205928_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001056491.1\|2205973_2206474_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000807651.1\|2206559_2206739_-	general stress protein	NA	NA	NA	NA
WP_000443067.1\|2207119_2207926_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000209520.1\|2207925_2209119_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_001344826.1\|2209130_2210489_-	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	8.6e-37	40.7
WP_000763511.1\|2210492_2212088_-	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
WP_001194584.1\|2212087_2213650_-	anthranilate synthase component I	NA	NA	NA	NA
WP_001700591.1\|2213741_2213786_-	trp operon leader peptide	NA	NA	NA	NA
WP_001285661.1\|2213923_2214805_+	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001295575.1\|2214801_2215422_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001291216.1\|2215522_2216395_+	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001278906.1\|2216434_2217025_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_000559281.1\|2217021_2217780_-	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	24.5
WP_000422045.1\|2217999_2219049_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5

DBSCAN-SWA_10

2295590 : 2392652

115

Escherichia_phage(41.38%)

integrase,tRNA,transposase,tail,head,terminase,capsid,holin

attL 2307409:2307427|attR 2371251:2371269

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000628065.1\|2295590_2296823_-	diguanylate cyclase DgcM	A0A127AWB9	Bacillus_phage	3.1e-17	39.5
WP_000387388.1\|2297077_2298061_+	zinc transporter ZntB	NA	NA	NA	NA
WP_000123745.1\|2298538_2299912_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
WP_001157407.1\|2300040_2300976_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
WP_000040839.1\|2301027_2302263_-\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	3.8e-241	99.5
WP_000079604.1\|2302264_2302480_-	excisionase XisR	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
WP_001302840.1\|2302579_2302768_-	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	5.5e-27	98.4
WP_001443846.1\|2302805_2302955_-	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	2.5e-22	95.9
WP_000166313.1\|2303010_2303820_-	recombination protein RecT	A0A1P8DTF2	Proteus_phage	4.0e-106	71.5
WP_000105140.1\|2303812_2306413_-	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	6.1e-249	63.5
WP_001344816.1\|2306514_2306790_-	hypothetical protein	A0A0U2QW85	Escherichia_phage	4.0e-42	95.6
WP_001352098.1\|2306864_2307035_-	conserved protein, Rac prophage	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
WP_000560223.1\|2307034_2307256_-	killing protein KilR	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
2307409:2307427	attL	NA	NA	NA	NA
WP_001312793.1\|2307697_2308186_+	superinfection exclusion protein B	NA	NA	NA	NA
WP_001169151.1\|2308182_2308338_-	YdaF family protein	M4QQ57	Salicola_phage	6.1e-08	55.3
WP_001326317.1\|2308348_2308528_-	hypothetical protein	NA	NA	NA	NA
WP_000233319.1\|2308770_2309190_-	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	5.5e-19	46.5
WP_001072342.1\|2309269_2309524_+	hypothetical protein	A0A2I6PIE5	Escherichia_phage	1.3e-18	61.6
WP_000693803.1\|2309520_2309943_+	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	1.3e-68	92.9
WP_001304174.1\|2310020_2310809_+	hypothetical protein	G9L6A8	Escherichia_phage	2.0e-41	64.3
WP_000788980.1\|2310815_2311562_+	ATP-binding protein	V5UQI5	Shigella_phage	5.6e-115	81.3
WP_000450712.1\|2311584_2312346_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	7.0e-121	90.5
WP_001141110.1\|2312361_2312784_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	3.1e-62	88.5
WP_000935420.1\|2312889_2313102_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.8e-33	94.3
WP_042350895.1\|2313187_2313352_+	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	2.0e-17	90.7
WP_000224233.1\|2313353_2313617_+	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
WP_000208018.1\|2313627_2313789_+	hypothetical protein	A0A192Y6F5	Salmonella_phage	3.2e-15	89.4
WP_000365100.1\|2313867_2314113_+	hypothetical protein	Q9G078	Enterobacteria_phage	5.9e-13	70.7
WP_001100703.1\|2314544_2315696_+	DNA cytosine methyltransferase	Q8JKX6	Natrialba_phage	1.0e-22	36.9
WP_047086260.1\|2315663_2316653_-	hypothetical protein	NA	NA	NA	NA
WP_000138556.1\|2316652_2318044_-	ATPase	NA	NA	NA	NA
WP_000940319.1\|2318543_2319143_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.1e-105	92.0
WP_000247761.1\|2319142_2319433_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.3e-47	87.5
WP_000640158.1\|2319429_2319984_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	5.0e-68	69.1
WP_000466957.1\|2320545_2320977_+	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
WP_000143077.1\|2321547_2323401_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.3
WP_000284522.1\|2323550_2323766_+\|holin	holin	Q6H9V8	Enterobacteria_phage	1.3e-32	97.2
WP_000731221.1\|2323770_2324115_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.8e-55	95.6
WP_000992086.1\|2324165_2324699_+	lysozyme	B6DZ92	Enterobacteria_phage	1.3e-100	97.7
WP_001344811.1\|2324972_2325512_+	ant domain protein	Q5MBW0	Stx1-converting_phage	3.0e-86	99.4
WP_085948178.1\|2325514_2326728_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000285960.1\|2326804_2326981_+	phage antirepressor	Q5MBW0	Stx1-converting_phage	3.3e-26	98.3
WP_001280923.1\|2327075_2327207_+	hypothetical protein	A0A0P0ZG36	Escherichia_phage	3.8e-11	93.0
WP_012817877.1\|2327429_2327615_+	membrane protein	A0A1U9AJA4	Stx1_converting_phage	4.0e-22	85.2
WP_000828070.1\|2328015_2328342_+	TonB family protein	H6WZK5	Escherichia_phage	6.3e-55	98.1
WP_000095744.1\|2328473_2328674_-	YlcI/YnfO family protein	H6WZK6	Escherichia_phage	1.3e-29	97.0
WP_000829192.1\|2328715_2329081_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
WP_000958380.1\|2329370_2329934_+\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_001411753.1\|2329930_2331592_+\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.3
WP_000173011.1\|2331655_2333593_+\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	99.7
WP_001063099.1\|2333637_2333859_+	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000125984.1\|2336223_2336550_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
WP_001007911.1\|2336559_2336910_+\|head	phage head closure protein	H6WZL5	Escherichia_phage	2.0e-59	100.0
WP_000573391.1\|2336906_2337353_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_000133393.1\|2337349_2337694_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_001275467.1\|2337762_2338479_+\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	4.7e-127	97.9
WP_001030041.1\|2338484_2338859_+\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	5.0e-64	98.4
WP_001453698.1\|2338954_2339164_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_000937595.1\|2341272_2342460_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000091308.1\|2342459_2342825_-	hypothetical protein	NA	NA	NA	NA
WP_001369428.1\|2342843_2344286_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	5.1e-229	93.3
WP_000807940.1\|2344278_2344620_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
WP_001369426.1\|2344619_2345318_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	7.6e-130	97.0
WP_001369422.1\|2345323_2346067_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	1.1e-147	97.2
WP_096860308.1\|2346012_2346645_+\|tail	tail assembly protein	A0A0P0ZC16	Stx2-converting_phage	2.3e-101	97.1
WP_000514717.1\|2346987_2350461_+	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	90.2
WP_001228290.1\|2350528_2351128_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	4.1e-108	97.0
WP_000216548.1\|2351279_2352584_+\|tail	tail fiber protein	A0A0P0ZCC1	Stx2-converting_phage	1.2e-72	95.4
WP_001023476.1\|2352585_2352855_+\|tail	phage tail protein	A0A1U9AJC2	Stx1_converting_phage	2.7e-43	97.8
WP_106409364.1\|2353969_2354092_+	hypothetical protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
WP_000950979.1\|2354198_2355110_+	type III secretion system effector kinase NleH1-2	A5LH48	Enterobacteria_phage	3.0e-134	82.2
WP_085948178.1\|2355656_2356870_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_001303943.1\|2357896_2358175_-	hypothetical protein	NA	NA	NA	NA
WP_001414184.1\|2358602_2358749_+	hypothetical protein	NA	NA	NA	NA
WP_001303944.1\|2358885_2359533_-	T3SS effector E3 ubiquitin-protein ligase NleG	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
WP_001144879.1\|2359716_2360307_+	T3SS effector guanine nucleotide exchange factor EspM1	NA	NA	NA	NA
WP_001261191.1\|2362812_2363166_-	recombinase family protein	NA	NA	NA	NA
WP_000171274.1\|2363256_2363976_+	TonB system transport protein TonB	NA	NA	NA	NA
WP_000108160.1\|2364015_2364414_-	acyl-CoA thioester hydrolase YciA	NA	NA	NA	NA
WP_000808667.1\|2364518_2365058_-	septation protein A	NA	NA	NA	NA
WP_000028540.1\|2365087_2365831_-	UPF0259 family protein	NA	NA	NA	NA
WP_000737224.1\|2366187_2366826_+	outer membrane protein OmpW	NA	NA	NA	NA
WP_000113674.1\|2366871_2368002_-\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	3.4e-103	51.4
WP_000113189.1\|2367979_2368228_-	excisionase	NA	NA	NA	NA
WP_000048484.1\|2368292_2370764_-	exonuclease	A0A192Y6E0	Salmonella_phage	5.5e-58	57.7
WP_000199480.1\|2370859_2371048_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449172.1\|2371044_2371233_-	cell division inhibitor	NA	NA	NA	NA
WP_001342117.1\|2371632_2371800_+	hypothetical protein	NA	NA	NA	NA
2371251:2371269	attR	NA	NA	NA	NA
WP_000920491.1\|2371793_2372027_+	hypothetical protein	NA	NA	NA	NA
WP_000394552.1\|2372004_2372412_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	7.0e-11	37.8
WP_001171894.1\|2372434_2372653_-	hypothetical protein	NA	NA	NA	NA
WP_001240336.1\|2372725_2373025_-	hypothetical protein	NA	NA	NA	NA
WP_000787428.1\|2373289_2373697_-	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	9.8e-29	49.6
WP_000705622.1\|2373983_2374535_+	hypothetical protein	NA	NA	NA	NA
WP_000020556.1\|2374506_2375547_+	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_157825328.1\|2375458_2376001_+	replication protein	A0A0U2JGJ0	Escherichia_phage	1.5e-85	98.7
WP_000450683.1\|2376034_2376769_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.9e-108	84.3
WP_001505071.1\|2376765_2376930_+	hypothetical protein	NA	NA	NA	NA
WP_001449026.1\|2377628_2378387_+	AcfC family adhesin Paa	NA	NA	NA	NA
WP_000961821.1\|2378665_2378878_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.3e-16	72.9
WP_001217394.1\|2379098_2379356_+	hypothetical protein	NA	NA	NA	NA
WP_032178572.1\|2379425_2379704_+	hypothetical protein	I6PCV7	Cronobacter_phage	2.8e-11	48.4
WP_001265289.1\|2379705_2380761_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	2.9e-88	47.6
WP_000140002.1\|2380761_2381127_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	67.5
WP_001059384.1\|2381123_2381813_+	antiterminator	I6PDF8	Cronobacter_phage	4.0e-59	51.1
WP_106898647.1\|2383337_2385122_+	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	96.8
WP_085948178.1\|2385147_2386360_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_064764776.1\|2386326_2386449_+	hypothetical protein	A0A0N7BTS3	Escherichia_phage	4.3e-09	86.1
WP_001023452.1\|2386450_2386720_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	6.4e-45	100.0
WP_000491542.1\|2386860_2387736_+	hypothetical protein	A0A0P0ZCT1	Stx2-converting_phage	1.5e-162	100.0
WP_001121225.1\|2387960_2388611_-	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_096245710.1\|2389206_2389521_-	DinI-like family protein	Q687E4	Enterobacteria_phage	1.3e-25	81.9
WP_000347482.1\|2389580_2390864_+	MHS family MFS transporter	NA	NA	NA	NA
WP_000527750.1\|2390952_2392413_+	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	5.6e-42	30.3
WP_000214712.1\|2392448_2392652_-	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2

DBSCAN-SWA_11

2531871 : 2652207

113

Stx2-converting_phage(40.38%)

lysis,integrase,terminase,holin,transposase,head,tail,capsid,protease,portal

attL 2612064:2612080|attR 2647436:2647452

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000826406.1\|2531871_2533080_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	9.2e-208	93.3
WP_001261013.1\|2533606_2534275_-	DUF3313 domain-containing protein	NA	NA	NA	NA
WP_000586732.1\|2534577_2535171_-	tellurite resistance methyltransferase TehB	NA	NA	NA	NA
WP_001341359.1\|2535167_2536160_-	dicarboxylate transporter/tellurite-resistance protein TehA	NA	NA	NA	NA
WP_001315480.1\|2536351_2537263_+	LbetaH domain-containing protein	NA	NA	NA	NA
WP_000140877.1\|2537257_2537794_-	50S ribosomal protein L7/L12-serine acetyltransferase	NA	NA	NA	NA
WP_001296778.1\|2537856_2538081_-	YdcH family protein	NA	NA	NA	NA
WP_000375956.1\|2538220_2539876_-	glucan biosynthesis protein	NA	NA	NA	NA
WP_000013783.1\|2540100_2541444_-	VOC family protein	NA	NA	NA	NA
WP_001345051.1\|2541660_2542584_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001098530.1\|2542621_2544262_-	methyl-accepting chemotaxis protein Trg	NA	NA	NA	NA
WP_001320773.1\|2544660_2544810_+	type I toxin-antitoxin system toxin HokB	NA	NA	NA	NA
WP_000731833.1\|2544881_2545055_-	periplasmic protein	A0A0R6PKG1	Moraxella_phage	4.4e-07	67.4
WP_001307188.1\|2545299_2545830_-	cytochrome b561	A0A0U2QLA7	Escherichia_phage	3.1e-19	44.9
WP_000048669.1\|2546018_2547020_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_001027942.1\|2548560_2549361_-	YdcF family protein	NA	NA	NA	NA
WP_000139621.1\|2549632_2553535_-	ATP-dependent RNA helicase HrpA	A0A1V0SIV3	Klosneuvirus	2.2e-53	29.5
WP_000048948.1\|2553735_2554341_+	FMN-dependent NADH-azoreductase	NA	NA	NA	NA
WP_000627379.1\|2554391_2555708_-	phosphatase PAP2/dual specificity phosphatase family protein	NA	NA	NA	NA
WP_000431813.1\|2555697_2557455_-	bifunctional alpha/beta hydrolase/class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000890909.1\|2557470_2558367_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_000177525.1\|2558366_2558972_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_000477179.1\|2559142_2561449_-	DUF2773 domain-containing bactofilin	NA	NA	NA	NA
WP_000097801.1\|2561512_2562373_-	pyridoxine 4-dehydrogenase	NA	NA	NA	NA
WP_001123455.1\|2562603_2563194_-	phenylacetic acid degradation protein PaaY	NA	NA	NA	NA
WP_000041176.1\|2563175_2564126_-	phenylacetic acid degradation operon negative regulatory protein PaaX	NA	NA	NA	NA
WP_000632286.1\|2564226_2565540_-	phenylacetate--CoA ligase	NA	NA	NA	NA
WP_001206190.1\|2565566_2566772_-	3-oxoadipyl-CoA thiolase	NA	NA	NA	NA
WP_000018413.1\|2566771_2567194_-	hydroxyphenylacetyl-CoA thioesterase PaaI	NA	NA	NA	NA
WP_000973362.1\|2567183_2568611_-	3-hydroxyacyl-CoA dehydrogenase PaaC	NA	NA	NA	NA
WP_000969777.1\|2568612_2569401_-	2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase	NA	NA	NA	NA
WP_001292353.1\|2569400_2570168_-	2,3-dehydroadipyl-CoA hydratase	NA	NA	NA	NA
WP_000206377.1\|2570164_2571235_-	phenylacetate-CoA oxygenase/reductase subunit PaaK	NA	NA	NA	NA
WP_001189197.1\|2571242_2571740_-	phenylacetate degradation protein PaaD	NA	NA	NA	NA
WP_001072831.1\|2571754_2572501_-	phenylacetate-CoA oxygenase subunit PaaC	NA	NA	NA	NA
WP_000073393.1\|2572509_2572797_-	1,2-phenylacetyl-CoA epoxidase subunit B	NA	NA	NA	NA
WP_000191073.1\|2572808_2573738_-	1,2-phenylacetyl-CoA epoxidase subunit A	NA	NA	NA	NA
WP_001186481.1\|2574022_2576068_+	phenylacetic acid degradation bifunctional protein PaaZ	NA	NA	NA	NA
WP_000535449.1\|2576315_2578589_+	primary-amine oxidase	NA	NA	NA	NA
WP_001067510.1\|2580368_2581274_+	transcriptional regulator FeaR	NA	NA	NA	NA
WP_001341369.1\|2581445_2581772_-	YdbL family protein	NA	NA	NA	NA
WP_000698141.1\|2581779_2581965_-	YnbE family lipoprotein	NA	NA	NA	NA
WP_000900925.1\|2581961_2584601_-	YdbH family protein	NA	NA	NA	NA
WP_000762229.1\|2584808_2585798_+	D-lactate dehydrogenase	M1I4S0	Paramecium_bursaria_Chlorella_virus	2.5e-70	44.0
WP_001295716.1\|2585908_2586331_+	heat shock protein HslJ	NA	NA	NA	NA
WP_001295715.1\|2586327_2586594_-	DUF333 domain-containing protein	NA	NA	NA	NA
WP_000628171.1\|2586867_2590392_+	pyruvate:ferredoxin (flavodoxin) oxidoreductase	NA	NA	NA	NA
WP_000837930.1\|2590758_2591892_+	porin OmpN	Q1MVN1	Enterobacteria_phage	1.2e-116	58.3
WP_001295593.1\|2592032_2592467_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.4e-28	52.8
WP_001143784.1\|2593047_2593689_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	6.8e-109	100.0
WP_001443810.1\|2593770_2594400_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.3e-77	92.2
WP_001131659.1\|2594472_2595048_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	5.3e-89	88.4
WP_001023992.1\|2595160_2595430_-\|tail	phage tail protein	A0A0P0ZCV7	Stx2-converting_phage	4.2e-44	95.5
WP_000268964.1\|2595431_2596745_-\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	9.7e-78	99.1
WP_001230550.1\|2596809_2597409_-	Ail/Lom family outer membrane beta-barrel protein	B6ETG5	Enterobacteria_phage	3.0e-111	100.0
WP_000515042.1\|2597479_2600977_-	host specificity protein J	A0A0P0ZEQ8	Stx2-converting_phage	0.0e+00	94.3
WP_106898648.1\|2601110_2601638_+	superoxide dismutase family protein	Q9MC02	Salmonella_phage	1.4e-59	60.5
WP_064732755.1\|2601828_2602461_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	3.4e-97	90.4
WP_000194763.1\|2602406_2603150_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.4e-150	99.2
WP_012817879.1\|2603160_2603859_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	4.0e-131	97.8
WP_000807964.1\|2603858_2604200_-\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
WP_000212770.1\|2604192_2607435_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	99.0
WP_001453698.1\|2607486_2607696_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030060.1\|2607791_2608166_-\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	3.0e-64	99.2
WP_001275445.1\|2608171_2608888_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	3.7e-124	95.8
WP_000133393.1\|2608954_2609299_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_000573391.1\|2609295_2609742_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007905.1\|2609738_2610089_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125990.1\|2610098_2610425_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZBH1	Stx2-converting_phage	9.2e-54	100.0
WP_106898649.1\|2610427_2613007_-\|portal	phage portal protein	A0A0P0ZDD0	Stx2-converting_phage	0.0e+00	98.4
2612064:2612080	attL	NA	NA	NA	NA
WP_001063025.1\|2612952_2613174_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_000173011.1\|2613218_2615156_-\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	99.7
WP_001369319.1\|2615219_2616881_-\|terminase	terminase large subunit	H6WZK9	Escherichia_phage	0.0e+00	98.9
WP_000958415.1\|2616877_2617441_-\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	3.8e-79	100.0
WP_000279803.1\|2617731_2618097_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	2.9e-64	96.7
WP_000095736.1\|2618138_2618366_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_000736096.1\|2618734_2618959_-	hypothetical protein	NA	NA	NA	NA
WP_012578895.1\|2619044_2619230_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	2.7e-18	98.4
WP_000992122.1\|2619747_2620281_-	lysozyme	A0A0N7KZF9	Stx2-converting_phage	2.8e-100	98.3
WP_000731236.1\|2620331_2620676_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-58	100.0
WP_000411811.1\|2620680_2620887_-\|holin	holin	O48430	Enterobacteria_phage	1.8e-31	100.0
WP_000143036.1\|2621332_2623183_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.4
WP_001344632.1\|2623629_2623761_-	DUF3927 family protein	H6WZJ7	Escherichia_phage	5.2e-08	85.7
WP_085948178.1\|2624016_2625229_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000476993.1\|2625448_2625676_-	transcriptional regulator	NA	NA	NA	NA
WP_001003381.1\|2625753_2626161_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	2.5e-24	46.2
WP_000379591.1\|2626353_2626506_+	DUF1391 family protein	M4QQ57	Salicola_phage	6.6e-07	53.2
WP_001344637.1\|2626517_2626883_+	hypothetical protein	NA	NA	NA	NA
WP_001328010.1\|2626851_2627139_-	hypothetical protein	NA	NA	NA	NA
WP_000854559.1\|2627554_2627743_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001083273.1\|2627739_2627931_+\|lysis	lysis protein YdfD	NA	NA	NA	NA
WP_000048302.1\|2628024_2630496_+	exonuclease	A0A192Y6E0	Salmonella_phage	3.2e-58	56.1
WP_001296941.1\|2630583_2630820_+	excisionase family protein	S4TND0	Salmonella_phage	6.1e-15	50.7
WP_000876990.1\|2630854_2632135_+\|integrase	site-specific integrase	B6DZ48	Enterobacteria_phage	1.9e-155	62.1
WP_001360138.1\|2632154_2632265_-	hypothetical protein	NA	NA	NA	NA
WP_000836079.1\|2632322_2633342_-	Zn-dependent oxidoreductase	E3SJ82	Synechococcus_phage	9.7e-17	25.9
WP_001295394.1\|2633353_2634568_-	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	1.4e-46	29.0
WP_000598292.1\|2634773_2635100_-	YnfA family protein	A0A218MNG8	uncultured_virus	9.9e-24	55.6
WP_000705211.1\|2635234_2635576_+	DUF1283 family protein	NA	NA	NA	NA
WP_001138581.1\|2635610_2636171_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_001321287.1\|2636173_2636884_-	YnfC family lipoprotein	NA	NA	NA	NA
WP_001307224.1\|2636991_2637297_+	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_001342196.1\|2639980_2642404_+	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	2.2e-208	48.6
WP_000213028.1\|2642414_2643032_+	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	9.5e-76	59.6
WP_000526492.1\|2643033_2643888_+	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_000148710.1\|2643930_2644545_+	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	8.7e-29	36.3
WP_071526378.1\|2644703_2645996_+	voltage-gated ClC-type chloride channel ClcB	NA	NA	NA	NA
WP_000919226.1\|2645948_2646644_-	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_000225276.1\|2646768_2647989_-	DNA-binding transcriptional repressor Mlc	NA	NA	NA	NA
2647436:2647452	attR	NA	NA	NA	NA
WP_001019545.1\|2648123_2649017_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000091840.1\|2649123_2650377_+	MFS transporter	NA	NA	NA	NA
WP_000233090.1\|2651202_2651286_+	hypothetical protein	NA	NA	NA	NA
WP_001260840.1\|2651385_2652207_+\|protease	serine protease	NA	NA	NA	NA

DBSCAN-SWA_12

2775686 : 2814102

Enterobacteria_phage(86.11%)

plate,holin,tail,transposase,tRNA,head,terminase,capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100206497.1\|2775686_2775965_+	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	6.2e-27	93.4
WP_000159459.1\|2775975_2776254_+	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	1.5e-33	78.3
WP_000514277.1\|2776265_2776508_+	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	2.3e-38	100.0
WP_085948178.1\|2776572_2777786_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000686506.1\|2779358_2780318_+	recombinase	A0A0A7NPX4	Enterobacteria_phage	7.1e-179	98.4
WP_000211267.1\|2780322_2780634_+	chromosome partitioning protein	A0A0A7NPT5	Enterobacteria_phage	2.2e-41	83.5
WP_000236489.1\|2781830_2782355_+	hypothetical protein	NA	NA	NA	NA
WP_000087824.1\|2782369_2783416_-\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.9e-201	99.1
WP_000613748.1\|2783415_2785167_-\|terminase	terminase	A0A0A7NV54	Enterobacteria_phage	0.0e+00	97.3
WP_001262673.1\|2785321_2786158_+\|capsid	phage capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	2.7e-150	100.0
WP_001055104.1\|2786181_2787234_+\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	1.3e-194	97.7
WP_000632344.1\|2787279_2788080_+\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	6.6e-130	91.4
WP_000063082.1\|2788182_2788677_+\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	2.7e-89	99.4
WP_000864901.1\|2788676_2788877_+\|tail	tail protein	A0A0A7NV57	Enterobacteria_phage	3.5e-32	100.0
WP_000104350.1\|2788879_2789203_+\|holin	holin	A0A0A7NRY9	Enterobacteria_phage	1.6e-50	99.1
WP_000072327.1\|2789199_2789592_+	M15 family metallopeptidase	A0A0A7NQ86	Enterobacteria_phage	5.8e-71	100.0
WP_000780569.1\|2789588_2789996_+	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	4.5e-66	98.5
WP_000920593.1\|2790133_2790601_+\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	1.0e-85	99.4
WP_000356341.1\|2790593_2791229_+\|tail	tail protein	A0A0A7NV60	Enterobacteria_phage	3.1e-114	99.5
WP_001271894.1\|2791225_2791807_+\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	1.0e-100	96.9
WP_000213447.1\|2791803_2792154_+\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	9.2e-60	100.0
WP_001111942.1\|2792157_2793054_+\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	1.1e-154	98.0
WP_000071739.1\|2793046_2793577_+\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	1.1e-93	99.4
WP_000108519.1\|2793579_2795712_+\|tail	phage tail protein	U5N099	Enterobacteria_phage	4.2e-131	66.7
WP_000144026.1\|2795711_2796290_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.7e-95	89.0
WP_000954196.1\|2796333_2796906_-	serine acetyltransferase	NA	NA	NA	NA
WP_000979957.1\|2797062_2797551_-\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	3.0e-85	99.4
WP_000853433.1\|2797563_2800371_-\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	94.9
WP_000333503.1\|2800357_2800513_-\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	9.7e-22	96.1
WP_000651581.1\|2800521_2800896_-\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	6.9e-37	73.2
WP_000290445.1\|2800951_2801464_-\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	7.8e-92	98.2
WP_000005431.1\|2801463_2802648_-\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	8.1e-225	99.0
WP_000132811.1\|2802805_2803915_+	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	9.6e-204	98.6
WP_001035742.1\|2804140_2805643_+	DNA-binding protein	NA	NA	NA	NA
WP_000488103.1\|2805886_2806147_+	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_000078923.1\|2806337_2806478_+	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	4.5e-18	95.7
WP_001229265.1\|2806784_2807084_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	7.2e-13	40.0
WP_000672378.1\|2807088_2809476_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_000018594.1\|2809490_2810474_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.4e-33	38.5
WP_001386830.1\|2810757_2810802_-	pheST operon leader peptide PheM	NA	NA	NA	NA
WP_000124850.1\|2810924_2811281_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_001124225.1\|2811333_2811531_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_001700733.1\|2811627_2812170_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	6.3e-15	32.9
WP_001144192.1\|2812173_2814102_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	3.2e-130	37.4

DBSCAN-SWA_13

3028227 : 3124129

111

Escherichia_phage(36.92%)

integrase,terminase,holin,transposase,head,tail,capsid,portal

attL 3121281:3121340|attR 3133855:3133955

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106898651.1\|3028227_3029440_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000287769.1\|3029556_3029967_+	flagellar export chaperone FliS	NA	NA	NA	NA
WP_001015023.1\|3029966_3030332_+	flagella biosynthesis regulatory protein FliT	NA	NA	NA	NA
WP_001245704.1\|3030409_3031897_+	alpha-amylase	NA	NA	NA	NA
WP_001344676.1\|3031930_3032344_-	lipoprotein	NA	NA	NA	NA
WP_000118907.1\|3032530_3033736_+	selenium metabolism membrane protein YedE/FdhT	NA	NA	NA	NA
WP_000790498.1\|3033732_3033966_+	sulfurtransferase-like selenium metabolism protein YedF	NA	NA	NA	NA
WP_000334609.1\|3034072_3034744_+	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	5.6e-82	60.8
WP_000826461.1\|3034783_3035992_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	4.9e-209	93.5
WP_000879833.1\|3037383_3038181_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000734033.1\|3038190_3038742_-	Raf kinase inhibitor-like protein YbcL	NA	NA	NA	NA
WP_001070440.1\|3038910_3039243_-	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_001274299.1\|3039576_3039891_-	flagellar hook-basal body complex protein FliE	NA	NA	NA	NA
WP_000994449.1\|3040104_3041763_+	flagellar basal body M-ring protein FliF	NA	NA	NA	NA
WP_000067950.1\|3041755_3042751_+	flagellar motor switch protein FliG	NA	NA	NA	NA
WP_001282694.1\|3042743_3043430_+	flagellar assembly protein FliH	NA	NA	NA	NA
WP_000213292.1\|3043429_3044803_+	flagellum-specific ATP synthase FliI	NA	NA	NA	NA
WP_000807584.1\|3044821_3045265_+	flagella biosynthesis chaperone FliJ	NA	NA	NA	NA
WP_000620091.1\|3045261_3046389_+	flagellar hook length control protein FliK	NA	NA	NA	NA
WP_000133124.1\|3046493_3046958_+	flagellar basal body-associated protein FliL	NA	NA	NA	NA
WP_001295641.1\|3046962_3047967_+	flagellar motor switch protein FliM	NA	NA	NA	NA
WP_001282098.1\|3047963_3048377_+	flagellar motor switch protein FliN	NA	NA	NA	NA
WP_001302429.1\|3048379_3048745_+	flagellar type III secretion system protein FliO	NA	NA	NA	NA
WP_001253450.1\|3048744_3049482_+	flagellar type III secretion system pore protein FliP	NA	NA	NA	NA
WP_000187358.1\|3049491_3049761_+	flagellar biosynthesis protein FliQ	NA	NA	NA	NA
WP_000942326.1\|3049768_3050554_+	flagellar type III secretion system protein FliR	NA	NA	NA	NA
WP_000103994.1\|3050843_3051467_+	transcriptional regulator RcsA	NA	NA	NA	NA
WP_071524607.1\|3051510_3051753_-	protein DsrB	NA	NA	NA	NA
WP_000844800.1\|3051861_3052089_+	peroxide/acid resistance protein YodD	NA	NA	NA	NA
WP_000949111.1\|3052386_3053202_+	mannosyl-3-phosphoglycerate phosphatase-related protein	NA	NA	NA	NA
WP_001377491.1\|3053198_3054893_-	cellulose biosynthesis regulator YedQ	A0A127AWB9	Bacillus_phage	1.3e-18	35.6
WP_000009309.1\|3055063_3055246_-	DUF2158 domain-containing protein	NA	NA	NA	NA
WP_000922683.1\|3055324_3056242_-	DUF808 domain-containing protein	NA	NA	NA	NA
WP_001210913.1\|3056414_3057335_+	drug/metabolite exporter YedA	NA	NA	NA	NA
WP_000786004.1\|3057323_3057794_-	very short patch repair endonuclease	E5E3X5	Burkholderia_phage	1.5e-33	47.6
WP_001157238.1\|3057774_3059193_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.8e-101	55.3
WP_000365565.1\|3059259_3059955_-	phosphohydrolase	A0A1D6Y7U0	Golden_Marseillevirus	2.1e-07	28.0
WP_001313057.1\|3059994_3060360_-	hypothetical protein	NA	NA	NA	NA
WP_000824375.1\|3060926_3062090_+	porin OmpC	Q1MVN1	Enterobacteria_phage	7.2e-109	56.2
WP_000218214.1\|3062680_3063532_+	protein deglycase HchA	NA	NA	NA	NA
WP_000826738.1\|3063639_3064998_-	two-component system sensor histidine kinase HprS	NA	NA	NA	NA
WP_001339045.1\|3064997_3065669_-	response regulator transcription factor HprR	W8CYM9	Bacillus_phage	5.4e-32	35.2
WP_000920136.1\|3065801_3066215_+	hydroxyisourate hydrolase	NA	NA	NA	NA
WP_000730130.1\|3066323_3067328_+	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_001240109.1\|3067328_3067964_+	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_122993428.1\|3068199_3068871_+	metal-binding protein ZinT	NA	NA	NA	NA
WP_001079074.1\|3069213_3069744_+	cytochrome b	A0A0U2QLA7	Escherichia_phage	1.9e-56	100.0
WP_122993429.1\|3070978_3071992_-	peptidase M85	NA	NA	NA	NA
WP_106898652.1\|3072667_3073981_-\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	5.7e-78	98.9
WP_001230459.1\|3074045_3074645_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	8.0e-112	100.0
WP_122996286.1\|3078433_3079066_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	1.0e-104	97.6
WP_001369128.1\|3079011_3079755_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	3.3e-147	98.0
WP_001152113.1\|3079760_3080459_-\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	4.7e-132	99.1
WP_000847298.1\|3080458_3080788_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_000081781.1\|3080784_3083397_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	96.0
WP_000533440.1\|3083377_3083791_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_000479045.1\|3083817_3084240_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	1.7e-71	98.6
WP_000235098.1\|3084253_3085006_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	4.9e-135	99.2
WP_000683079.1\|3085013_3085409_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	1.5e-58	82.4
WP_000974980.1\|3085405_3085939_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.6e-58	66.7
WP_001204554.1\|3085954_3086308_-\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	1.5e-41	70.1
WP_000201501.1\|3086300_3086684_-	DNA-packaging protein FI	NA	NA	NA	NA
WP_000522591.1\|3086735_3087764_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	3.6e-112	61.0
WP_000256823.1\|3087821_3088169_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	8.9e-23	58.1
WP_001253979.1\|3088205_3089711_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.0e-99	53.5
WP_001369121.1\|3089700_3091293_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	7.1e-184	60.9
WP_000259002.1\|3091289_3091496_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_001426431.1\|3091479_3093408_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	3.6e-262	66.4
WP_001426432.1\|3093379_3093886_-	DNA-packaging protein	O64316	Escherichia_phage	7.4e-34	47.3
WP_001444498.1\|3094312_3094537_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	1.3e-19	90.6
WP_001302717.1\|3094618_3094933_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_012817896.1\|3095460_3095646_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	4.0e-22	83.6
WP_001092858.1\|3096163_3096697_-	lysozyme	Q6H9V6	Enterobacteria_phage	1.9e-101	96.0
WP_000284516.1\|3097259_3097475_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	7.7e-33	97.2
WP_001290231.1\|3097551_3097824_-	DUF826 domain-containing protein	A0A0P0ZBB8	Stx2-converting_phage	2.2e-21	100.0
WP_000143458.1\|3097864_3098044_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_000023159.1\|3098181_3100119_-	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	0.0e+00	96.9
WP_153244796.1\|3100104_3100248_+	hypothetical protein	H6WZJ8	Escherichia_phage	3.7e-15	97.4
WP_000466957.1\|3100597_3101029_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
WP_000422741.1\|3101116_3101542_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|3101538_3101889_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080194.1\|3101919_3103533_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	4.4e-181	64.0
WP_000301789.1\|3104018_3104732_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000917764.1\|3104866_3105064_-	hypothetical protein	S5MQK8	Escherichia_phage	6.8e-28	98.5
WP_000640033.1\|3105287_3105842_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	8.0e-66	67.4
WP_001217447.1\|3105850_3106210_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.0e-37	63.5
WP_001265229.1\|3106222_3107272_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.6
WP_000191872.1\|3107273_3107546_-	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_000756596.1\|3107667_3108012_-	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_000935259.1\|3108131_3108344_-	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_000104474.1\|3108577_3109135_-	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
WP_000683609.1\|3109136_3109355_-	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	2.3e-21	72.2
WP_000034815.1\|3109482_3109794_-	hypothetical protein	A0A0U2QV73	Escherichia_phage	1.6e-55	91.3
WP_000699809.1\|3109786_3110014_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
WP_000603384.1\|3110010_3110292_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
WP_000450617.1\|3110324_3111041_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.1e-71	62.6
WP_000788760.1\|3111062_3111809_-	ATP-binding protein	A0A088CBP4	Shigella_phage	3.6e-114	83.2
WP_001262366.1\|3111815_3112886_-	hypothetical protein	A0A088CD36	Shigella_phage	1.7e-64	65.7
WP_000693883.1\|3112957_3113383_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000391948.1\|3113366_3113648_-	hypothetical protein	K7PHA1	Enterobacteria_phage	8.5e-24	72.6
WP_000362152.1\|3113747_3114167_+	hypothetical protein	K7PK07	Enterobacteria_phage	4.0e-25	65.1
WP_001345283.1\|3114433_3114586_+	DUF1391 family protein	M4QQ57	Salicola_phage	1.7e-07	53.2
WP_000394546.1\|3114597_3115236_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_001133034.1\|3115236_3115446_-	hypothetical protein	NA	NA	NA	NA
WP_000449192.1\|3116016_3116205_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001090200.1\|3116201_3116393_+	DUF1482 family protein	NA	NA	NA	NA
WP_106898673.1\|3116953_3118167_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_001300307.1\|3120406_3121204_+	DgsA anti-repressor MtfA	NA	NA	NA	NA
3121281:3121340	attL	NA	NA	NA	NA
WP_001345280.1\|3121559_3122834_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.4e-76	40.9
WP_096950631.1\|3122821_3122950_-	AMP nucleosidase	A0A0N7BTS3	Escherichia_phage	2.8e-06	96.0
WP_106898653.1\|3122915_3124129_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	8.4e-169	99.3
3133855:3133955	attR	NA	NA	NA	NA

DBSCAN-SWA_14

3345201 : 3414080

Enterobacteria_phage(20.69%)

integrase,transposase,terminase,capsid,protease,holin

attL 3383144:3383179|attR 3415020:3415055

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000101907.1\|3345201_3346443_+\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	1.6e-98	43.1
WP_000387403.1\|3346939_3347146_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_001345228.1\|3347100_3348909_+	host cell division inhibitor Icd-like protein	A0A2H4JGN8	uncultured_Caudovirales_phage	2.9e-08	41.1
WP_023981888.1\|3349124_3349364_+	hypothetical protein	NA	NA	NA	NA
WP_001204078.1\|3349336_3349570_+	hypothetical protein	NA	NA	NA	NA
WP_001205000.1\|3349562_3349796_+	hypothetical protein	NA	NA	NA	NA
WP_000770163.1\|3349801_3350101_+	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_000833625.1\|3350097_3351498_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.6e-115	60.1
WP_001080641.1\|3351699_3351945_+	hypothetical protein	NA	NA	NA	NA
WP_000391151.1\|3352075_3352270_+	hypothetical protein	NA	NA	NA	NA
WP_001018604.1\|3352273_3352435_+	hypothetical protein	NA	NA	NA	NA
WP_001229488.1\|3352562_3353051_+\|terminase	terminase small subunit	A0A0P0ZCQ9	Stx2-converting_phage	3.9e-24	41.7
WP_001369202.1\|3353213_3354137_+\|capsid	phage capsid protein	A0A0R6PHC6	Moraxella_phage	1.2e-13	24.9
WP_001113637.1\|3357514_3358162_+	nitrate/nitrite response regulator protein NarP	NA	NA	NA	NA
WP_001211568.1\|3358196_3359249_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_000824439.1\|3359245_3359803_-	thiol:disulfide interchange protein DsbE	NA	NA	NA	NA
WP_000982426.1\|3359799_3361743_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_001026418.1\|3361739_3362219_-	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_000186540.1\|3362215_3362425_-	heme exporter protein CcmD	NA	NA	NA	NA
WP_001295447.1\|3362421_3363159_-	heme exporter protein CcmC	NA	NA	NA	NA
WP_000971722.1\|3363200_3363863_-	heme exporter protein CcmB	NA	NA	NA	NA
WP_000888560.1\|3363859_3364477_-	cytochrome c biogenesis heme-transporting ATPase CcmA	G3M9Y6	Bacillus_virus	1.9e-12	25.5
WP_000528376.1\|3364495_3365098_-	cytochrome c-type protein NapC	NA	NA	NA	NA
WP_000835176.1\|3365107_3365557_-	nitrate reductase cytochrome c-type subunit	NA	NA	NA	NA
WP_000013506.1\|3365553_3366417_-	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
WP_000091291.1\|3366403_3367099_-	ferredoxin-type protein NapG	NA	NA	NA	NA
WP_000778069.1\|3367105_3369592_-	nitrate reductase catalytic subunit NapA	NA	NA	NA	NA
WP_000557378.1\|3369588_3369852_-	chaperone NapD	NA	NA	NA	NA
WP_000686723.1\|3369841_3370336_-	ferredoxin-type protein NapF	NA	NA	NA	NA
WP_000849214.1\|3370744_3371233_+\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_000758043.1\|3371381_3373028_-	malate dehydrogenase (quinone)	NA	NA	NA	NA
WP_000422230.1\|3373245_3374889_-	microcin J25 efflux ABC transporter YojI	W8CYL7	Bacillus_phage	9.5e-14	24.0
WP_000884922.1\|3374964_3375615_-	DNA oxidative demethylase AlkB	A0A2K9L3R7	Tupanvirus	1.4e-05	31.7
WP_000786386.1\|3375614_3376679_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	1.8e-18	50.5
WP_000406116.1\|3376752_3377808_-	FAD:protein FMN transferase ApbE	NA	NA	NA	NA
WP_000865576.1\|3377919_3379011_-	porin OmpC	Q1MVN1	Enterobacteria_phage	9.4e-119	60.1
WP_001249151.1\|3379749_3382422_+	phosphotransferase RcsD	NA	NA	NA	NA
WP_001061917.1\|3382438_3383089_+	transcriptional regulator RcsB	NA	NA	NA	NA
3383144:3383179	attL	NA	NA	NA	NA
WP_000876032.1\|3383288_3386138_-	two-component system sensor histidine kinase RcsC	A0A1V0SGX0	Hokovirus	1.4e-41	27.2
WP_001225855.1\|3386412_3387189_-	YfaP family protein	NA	NA	NA	NA
WP_001104541.1\|3387193_3388843_-	DUF2300 domain-containing protein	NA	NA	NA	NA
WP_122993426.1\|3388843_3393238_-	alpha-2-macroglobulin family protein	NA	NA	NA	NA
WP_001025665.1\|3394039_3395362_+	type III secretion system effector NleA	H6WZN2	Escherichia_phage	9.7e-227	85.5
WP_072145794.1\|3396055_3396712_-	T3SS effector NleG family protein	B6DZC0	Enterobacteria_phage	2.5e-34	43.0
WP_000881317.1\|3396608_3397193_-	hypothetical protein	A0A0N7CEE8	Salmonella_phage	1.4e-84	89.1
WP_085948178.1\|3397603_3398817_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000075144.1\|3399089_3399587_-	lysozyme	A0A1B5FP97	Escherichia_phage	1.9e-90	98.2
WP_000284524.1\|3399586_3399802_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_012578864.1\|3399944_3400343_+	hypothetical protein	H6WZJ8	Escherichia_phage	6.9e-11	83.3
WP_000499454.1\|3400423_3400582_-	DUF3927 family protein	NA	NA	NA	NA
WP_001235460.1\|3401674_3402298_-	antitermination protein	K7PM87	Enterobacteria_phage	9.8e-113	98.6
WP_001028854.1\|3402294_3402960_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001223927.1\|3402956_3403559_-	recombination protein NinG	A0A1U9AJF8	Stx1_converting_phage	1.6e-91	94.6
WP_001108084.1\|3403533_3404100_-	endonuclease	A0A1U9AJK5	Stx1_converting_phage	6.6e-108	99.5
WP_042352449.1\|3404635_3405568_+	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	6.1e-151	99.7
WP_001345214.1\|3405606_3406434_+	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	1.6e-150	99.6
WP_001254228.1\|3406937_3407120_-	NinE family protein	A0A1U9AJF6	Stx1_converting_phage	1.1e-29	100.0
WP_001281192.1\|3407276_3407621_+	hypothetical protein	K7PJY7	Enterobacterial_phage	5.3e-60	100.0
WP_001444001.1\|3407726_3407945_+	excisionase	K7PKU2	Enterobacteria_phage	2.4e-34	98.6
WP_000533670.1\|3407922_3408993_+\|integrase	tyrosine-type recombinase/integrase	K7PHK0	Enterobacteria_phage	1.1e-196	98.0
WP_000012296.1\|3409615_3411304_-	DUF2138 domain-containing protein	NA	NA	NA	NA
WP_001281242.1\|3411452_3414080_-	DNA topoisomerase (ATP-hydrolyzing) subunit A	G3M9Z5	Bacillus_virus	8.1e-92	30.4
3415020:3415055	attR	NA	NA	NA	NA

DBSCAN-SWA_15

3502754 : 3596420

105

Escherichia_phage(53.16%)

lysis,integrase,terminase,holin,tRNA,transposase,bacteriocin,tail,capsid,protease,portal

attL 3534306:3534330|attR 3596615:3596639

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001283576.1\|3502754_3503567_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_001289165.1\|3503566_3504580_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000699121.1\|3504645_3505782_-	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	5.9e-23	29.1
WP_000615813.1\|3505880_3506876_+	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_000127749.1\|3506872_3508051_-	MFS transporter	NA	NA	NA	NA
WP_000817178.1\|3508334_3509555_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_000683806.1\|3509713_3511720_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_000559764.1\|3511840_3512119_-	YfcL family protein	NA	NA	NA	NA
WP_001089232.1\|3512152_3512701_-	elongation factor P hydroxylase	NA	NA	NA	NA
WP_000447359.1\|3512700_3513510_-	TSUP family transporter	NA	NA	NA	NA
WP_001043815.1\|3513509_3514334_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_000918470.1\|3514337_3515423_-	chorismate synthase	A0A291AU41	Pandoravirus	9.1e-90	48.4
WP_001295704.1\|3515457_3516390_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_000730806.1\|3516555_3517107_+	endonuclease SmrB	NA	NA	NA	NA
WP_001315753.1\|3517179_3518031_-	DUF2544 domain-containing protein	NA	NA	NA	NA
WP_000844750.1\|3518032_3518572_-	fimbrial protein	NA	NA	NA	NA
WP_000714139.1\|3518568_3519057_-	fimbrial protein	NA	NA	NA	NA
WP_000018471.1\|3519053_3519563_-	fimbrial protein	NA	NA	NA	NA
WP_000482748.1\|3519578_3520331_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_001112824.1\|3520350_3522996_-	fimbrial usher protein YfcU	NA	NA	NA	NA
WP_000033328.1\|3523077_3523641_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_001195819.1\|3524324_3524810_-	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_000426169.1\|3525012_3527157_-	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_000531954.1\|3527156_3528467_-	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_106898655.1\|3528646_3528931_-	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_001296861.1\|3529302_3530643_+	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_000937833.1\|3531009_3532068_+	hypothetical protein	NA	NA	NA	NA
WP_000776768.1\|3532249_3533005_-	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_000368131.1\|3533298_3534231_+	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
3534306:3534330	attL	NA	NA	NA	NA
WP_000012450.1\|3542872_3544138_-	hypothetical protein	A0A1I9LJU3	Stx_converting_phage	1.4e-206	100.0
WP_000540391.1\|3544148_3544400_-\|bacteriocin	bacteriocin	A0A2R2Z351	Escherichia_phage	7.9e-13	100.0
WP_085948178.1\|3544628_3545842_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000509481.1\|3546171_3546828_-	hypothetical protein	A0A2R2Z361	Escherichia_phage	2.4e-109	100.0
WP_000035558.1\|3546921_3547323_-	hypothetical protein	A0A2R2Z359	Escherichia_phage	3.7e-73	100.0
WP_000078907.1\|3547379_3547520_-	Hok/Gef family protein	A0A2R2X2B4	Escherichia_phage	3.1e-19	100.0
WP_000835359.1\|3547752_3548487_-	Ail/Lom family outer membrane beta-barrel protein	A0A0N7C1B9	Escherichia_phage	2.2e-135	99.6
WP_001301884.1\|3548577_3549195_-	hypothetical protein	A0A2R2Z362	Escherichia_phage	1.1e-121	100.0
WP_000455634.1\|3549200_3549479_-	outer membrane protein	A0A2R2Z367	Escherichia_phage	1.1e-50	100.0
WP_000197192.1\|3549493_3550762_-	host specificity protein J	A0A2R2Z364	Escherichia_phage	4.9e-220	100.0
WP_001146326.1\|3550758_3552384_-	hypothetical protein	A0A1I9LJT3	Stx_converting_phage	0.0e+00	100.0
WP_001303606.1\|3552678_3552867_-	hypothetical protein	A0A2R2Z344	Escherichia_phage	6.9e-30	100.0
WP_001024006.1\|3553006_3553276_-\|tail	phage tail protein	A0A1I9LJT0	Stx_converting_phage	2.2e-45	100.0
WP_024183271.1\|3553277_3555314_-\|tail	tail fiber protein	A0A0P0ZD90	Stx2-converting_phage	9.4e-88	100.0
WP_000207923.1\|3555310_3555961_-	hypothetical protein	A0A2R2X2B3	Escherichia_phage	7.8e-121	100.0
WP_000829200.1\|3555960_3556524_-	hypothetical protein	A0A2R2Z349	Escherichia_phage	3.2e-102	100.0
WP_001290743.1\|3556507_3556969_-	hypothetical protein	A0A2R2Z354	Escherichia_phage	7.8e-75	100.0
WP_001140442.1\|3557018_3557408_-	hypothetical protein	A0A2R2Z353	Escherichia_phage	9.9e-63	100.0
WP_000214474.1\|3557463_3558678_-\|capsid	N4-gp56 family major capsid protein	A0A2R2Z358	Escherichia_phage	1.3e-233	100.0
WP_000345010.1\|3558701_3559709_-	hypothetical protein	A0A2R2Z355	Escherichia_phage	2.3e-180	100.0
WP_000787519.1\|3559866_3562011_-\|portal	portal protein	A0A2R2Z346	Escherichia_phage	0.0e+00	100.0
WP_000143988.1\|3562010_3563717_-\|terminase	terminase	A0A2R2Z350	Escherichia_phage	0.0e+00	100.0
WP_001086069.1\|3563697_3564504_-\|terminase	terminase	A0A2R2Z334	Escherichia_phage	7.6e-134	100.0
WP_001301714.1\|3564559_3564763_-	hypothetical protein	A0A2R2Z338	Escherichia_phage	7.7e-35	100.0
WP_000738505.1\|3564912_3565206_+	serum resistance lipoprotein Bor	A0A2R2X2B2	Escherichia_phage	6.8e-48	100.0
WP_001082654.1\|3565237_3565702_-\|lysis	lysis protein	A0A2R2Z341	Escherichia_phage	5.8e-78	100.0
WP_000455406.1\|3565709_3565859_-	hypothetical protein	A0A0P0ZFU6	Escherichia_phage	2.4e-17	100.0
WP_001056885.1\|3565858_3566428_-	hypothetical protein	A0A2R2Z339	Escherichia_phage	1.8e-105	100.0
WP_000087461.1\|3566702_3567236_-	lysozyme	V5USG4	Shigella_phage	7.9e-103	100.0
WP_000284506.1\|3567240_3567456_-\|holin	holin	Q9ZWW2	Enterobacteria_phage	6.9e-34	100.0
WP_001290212.1\|3567532_3567805_-	DUF826 domain-containing protein	A0A1I9LJR2	Stx_converting_phage	1.2e-22	100.0
WP_000143458.1\|3567845_3568025_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_106898657.1\|3568159_3570097_-	SASA family carbohydrate esterase	G9L6J1	Escherichia_phage	0.0e+00	99.2
WP_000738068.1\|3570582_3570852_-	Shiga toxin Stx2a subunit B	A0A2R2Z326	Escherichia_phage	1.2e-43	100.0
WP_000649753.1\|3570863_3571823_-	Shiga toxin Stx2c subunit A	Q776Q3	Enterobacteria_phage	5.6e-176	100.0
WP_001204880.1\|3572604_3573039_-	antitermination protein	G9L695	Escherichia_phage	2.8e-82	100.0
WP_000144764.1\|3573031_3573226_-	protein ninH	G9L694	Escherichia_phage	1.9e-30	100.0
WP_001107963.1\|3573222_3573828_-	recombination protein NinG	A0A0P0ZCS9	Stx2-converting_phage	1.7e-98	100.0
WP_001004009.1\|3573827_3574550_-	DNA-binding protein	A0A0P0ZBS6	Stx2-converting_phage	1.3e-129	100.0
WP_000211423.1\|3574624_3575359_-	phage antirepressor Ant	A0A0N7C203	Escherichia_phage	5.5e-123	99.6
WP_001254256.1\|3575633_3575816_-	NinE family protein	A0A0N7C1X3	Escherichia_phage	5.7e-29	100.0
WP_000153270.1\|3575812_3576340_-	phage N-6-adenine-methyltransferase	K7PJZ4	Enterobacterial_phage	9.5e-101	100.0
WP_001304104.1\|3576336_3576783_-	recombination protein NinB	A0A1I9LJP8	Stx_converting_phage	2.4e-81	100.0
WP_001281772.1\|3576739_3576976_-	restriction alleviation protein, Lar family	Q8HA09	Enterobacteria_phage	1.2e-39	100.0
WP_085948178.1\|3577165_3578379_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000818843.1\|3578659_3578866_-	hypothetical protein	G9L683	Escherichia_phage	2.7e-27	100.0
WP_001036031.1\|3578938_3579208_-	hypothetical protein	Q08J36	Stx2-converting_phage	4.9e-45	100.0
WP_000131492.1\|3579207_3580644_-	AAA family ATPase	Q8VNP7	Enterobacteria_phage	6.1e-275	100.0
WP_000065668.1\|3580633_3581533_-	hypothetical protein	Q8VNP8	Enterobacteria_phage	1.6e-164	100.0
WP_000166207.1\|3581525_3581672_-	DUF2740 family protein	Q687G5	Enterobacteria_phage	1.1e-19	100.0
WP_000438528.1\|3581704_3582001_-	hypothetical protein	Q08J40	Stx2-converting_phage	5.2e-48	100.0
WP_001180318.1\|3582139_3582367_-	transcriptional regulator	G9L677	Escherichia_phage	7.8e-36	100.0
WP_000250473.1\|3582445_3583153_+	helix-turn-helix transcriptional regulator	G9L676	Escherichia_phage	1.5e-133	100.0
WP_000885202.1\|3583213_3583555_+	DUF3024 domain-containing protein	G9L675	Escherichia_phage	5.1e-63	100.0
WP_001221211.1\|3583622_3584084_+	hypothetical protein	G9L674	Escherichia_phage	1.3e-77	100.0
WP_000957426.1\|3584077_3585124_+	serine/threonine protein kinase	G9L673	Escherichia_phage	5.2e-207	100.0
WP_000198445.1\|3585780_3586164_+	hypothetical protein	Q08J47	Stx2-converting_phage	3.9e-64	100.0
WP_000167595.1\|3586222_3586693_+	hypothetical protein	A0A1I9LJN4	Stx_converting_phage	3.7e-88	100.0
WP_001198861.1\|3586883_3587048_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q776Q5	Enterobacteria_phage	1.1e-26	100.0
WP_000372941.1\|3587016_3587160_+	host cell division inhibitory peptide Kil	A0A1I9LJN2	Stx_converting_phage	1.2e-18	100.0
WP_000995439.1\|3587235_3587532_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000100845.1\|3587537_3588323_+	phage recombination protein Bet	A0A0N7KZJ3	Stx2-converting_phage	1.1e-148	100.0
WP_000186866.1\|3588319_3589000_+	YqaJ viral recombinase family protein	A0A0P0ZBV6	Stx2-converting_phage	2.1e-132	100.0
WP_000682304.1\|3588996_3589179_+	DUF1317 domain-containing protein	A0A0P0ZD61	Stx2-converting_phage	7.4e-29	100.0
WP_000548528.1\|3589151_3589343_+	DUF1382 family protein	A0A0P0ZC60	Stx2-converting_phage	5.6e-27	100.0
WP_001447688.1\|3589353_3589635_+	hypothetical protein	Q08J56	Stx2-converting_phage	6.5e-48	100.0
WP_000763383.1\|3589733_3589955_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.9e-35	100.0
WP_001289935.1\|3589951_3590725_+	ead/Ea22-like family protein	Q08J58	Stx2-converting_phage	1.0e-143	100.0
WP_000797281.1\|3590876_3591065_+	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	2.8e-31	100.0
WP_000951706.1\|3591066_3591276_+	hypothetical protein	A0A077SL56	Escherichia_phage	4.2e-36	100.0
WP_000203836.1\|3592743_3593367_+	phage antirepressor Ant	A0A0P0ZAZ7	Stx2-converting_phage	1.7e-112	100.0
WP_000669287.1\|3593409_3593577_+	hypothetical protein	A0A0P0ZCR2	Stx2-converting_phage	2.9e-27	100.0
WP_106898674.1\|3594443_3594602_+	DUF1382 family protein	A0A2R2X2A7	Escherichia_phage	1.1e-20	98.1
WP_000994801.1\|3594637_3595006_+	DUF1627 domain-containing protein	A0A0P0ZCA9	Stx2-converting_phage	8.8e-53	100.0
WP_000453637.1\|3595084_3595267_+	helix-turn-helix domain-containing protein	A0A2R2Z2X2	Escherichia_phage	4.1e-27	100.0
WP_001218308.1\|3595250_3596420_-\|integrase	site-specific integrase	A0A2R2Z2Y0	Escherichia_phage	1.7e-230	100.0
3596615:3596639	attR	NA	NA	NA	NA

DBSCAN-SWA_16

3826107 : 3938983

106

Enterobacteria_phage(54.0%)

terminase,tRNA,transposase,tail,protease,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001298974.1\|3826107_3826845_-\|tRNA	tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase TrmN	NA	NA	NA	NA
WP_000219193.1\|3826976_3828311_+	ATP-dependent RNA helicase SrmB	E3T5E1	Cafeteria_roenbergensis_virus	2.9e-45	30.8
WP_000365855.1\|3828520_3829402_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000189207.1\|3829505_3830093_+	cysteine/O-acetylserine transporter	NA	NA	NA	NA
WP_000627807.1\|3830148_3830532_-	autonomous glycyl radical cofactor GrcA	Q7Y524	Enterobacteria_phage	1.4e-32	72.0
WP_001262716.1\|3830835_3831525_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	7.1e-56	48.8
WP_000997403.1\|3831572_3832610_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_001098726.1\|3832816_3833236_+	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_001341635.1\|3833304_3834003_+	DTW domain-containing protein	NA	NA	NA	NA
WP_000083007.1\|3834034_3836695_+	protein lysine acetyltransferase	NA	NA	NA	NA
WP_000949265.1\|3836808_3838164_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_001300818.1\|3838209_3838533_+	YfiM family lipoprotein	NA	NA	NA	NA
WP_000841103.1\|3838529_3839828_-	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	1.3e-45	32.2
WP_001235102.1\|3845680_3848254_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000040115.1\|3848383_3849115_-	polyphenol oxidase	NA	NA	NA	NA
WP_000079107.1\|3849111_3850092_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000197686.1\|3850226_3850964_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000178456.1\|3851234_3851576_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_001386991.1\|3851679_3851727_+	hypothetical protein	NA	NA	NA	NA
WP_000200116.1\|3851825_3852986_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_000225214.1\|3853028_3854150_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_001168054.1\|3854160_3855231_-	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	5.3e-90	51.2
WP_000976004.1\|3855440_3855806_+	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_001212391.1\|3855955_3856474_+	YfiR family protein	NA	NA	NA	NA
WP_000969032.1\|3856463_3857690_+	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_000589821.1\|3857705_3858188_+	OmpA family protein	NA	NA	NA	NA
WP_000065253.1\|3858264_3858612_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000264774.1\|3858653_3859421_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000043335.1\|3859451_3860000_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000256450.1\|3860018_3860267_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_000460032.1\|3860515_3861877_-	signal recognition particle protein	NA	NA	NA	NA
WP_001338897.1\|3862043_3862835_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_010723175.1\|3862855_3864142_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001296310.1\|3864196_3864790_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_001059169.1\|3864912_3865791_+	NAD(+) kinase	NA	NA	NA	NA
WP_000880910.1\|3865876_3867538_+	DNA repair protein RecN	NA	NA	NA	NA
WP_001203437.1\|3867686_3868028_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_001117838.1\|3868089_3868380_-	RnfH family protein	NA	NA	NA	NA
WP_000600190.1\|3868369_3868846_-	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_000162574.1\|3868977_3869460_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_001217540.1\|3870308_3870557_+	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-38	100.0
WP_001023452.1\|3870924_3871194_-\|tail	phage tail protein	Q687E5	Enterobacteria_phage	6.4e-45	100.0
WP_106898659.1\|3871195_3872509_-\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	1.5e-78	99.3
WP_001230459.1\|3872573_3873173_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	8.0e-112	100.0
WP_106898660.1\|3873239_3876716_-	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	99.7
WP_122996286.1\|3876962_3877595_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	1.0e-104	97.6
WP_001369128.1\|3877540_3878284_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	3.3e-147	98.0
WP_001152113.1\|3878289_3878988_-\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	4.7e-132	99.1
WP_000847298.1\|3878987_3879317_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_000918236.1\|3879313_3881959_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	99.8
WP_000532073.1\|3882002_3882311_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	1.3e-54	100.0
WP_000479043.1\|3882337_3882760_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	5.1e-73	100.0
WP_000235090.1\|3882773_3883526_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	5.8e-136	100.0
WP_001444799.1\|3883533_3883824_-\|tail	tail protein	Q9EYD7	Enterobacteria_phage	2.1e-49	99.0
WP_085948178.1\|3883878_3885091_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000682711.1\|3885094_3885241_-	hypothetical protein	Q687G0	Enterobacteria_phage	3.5e-21	100.0
WP_106898661.1\|3885253_3885877_-\|tail	phage tail protein	Q8VNN3	Enterobacteria_phage	2.0e-105	99.5
WP_001281348.1\|3885879_3886161_-	DNA breaking-rejoining protein	Q8VNN4	Enterobacteria_phage	2.1e-46	100.0
WP_001097065.1\|3886153_3886480_-	DUF2190 family protein	Q9EYD5	Enterobacteria_phage	6.1e-50	100.0
WP_001114424.1\|3886567_3888592_-\|protease	Clp protease ClpP	S5M7Q8	Escherichia_phage	0.0e+00	99.8
WP_000974564.1\|3888536_3890039_-\|portal	phage portal protein	Q9EYD2	Enterobacteria_phage	4.8e-291	100.0
WP_000102413.1\|3890038_3890251_-	hypothetical protein	Q687G1	Enterobacteria_phage	2.3e-29	98.6
WP_001077625.1\|3890247_3892371_-\|terminase	phage terminase large subunit family protein	Q9EYD1	Enterobacteria_phage	0.0e+00	100.0
WP_000373407.1\|3892367_3892844_-	DUF1441 family protein	Q8VNN8	Enterobacteria_phage	3.3e-84	100.0
WP_012816791.1\|3893318_3893504_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000752026.1\|3894507_3894777_-	Shiga toxin Stx1a subunit B	Q7AYI7	Enterobacteria_phage	1.6e-43	100.0
WP_000691354.1\|3894786_3895734_-	Shiga toxin Stx1 subunit A	Q777W4	Enterobacteria_phage	3.2e-171	100.0
WP_001204849.1\|3896240_3896675_-	antitermination protein	Q8VNP1	Enterobacteria_phage	4.3e-83	100.0
WP_000144764.1\|3896667_3896862_-	protein ninH	G9L694	Escherichia_phage	1.9e-30	100.0
WP_001108006.1\|3896858_3897464_-	recombination protein NinG	Q8VNP2	Enterobacteria_phage	1.9e-97	100.0
WP_085948178.1\|3898207_3899421_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000214990.1\|3900981_3902730_-	hypothetical protein	A0A1B5FPH1	Escherichia_phage	0.0e+00	99.8
WP_001426837.1\|3902731_3904450_-	ATP-binding protein	A0A1B5FPD5	Escherichia_phage	5.5e-307	99.7
WP_000993087.1\|3906010_3906988_+	carbon starvation induced protein CsiD	NA	NA	NA	NA
WP_000271938.1\|3907007_3908276_+	L-2-hydroxyglutarate oxidase	NA	NA	NA	NA
WP_000772858.1\|3908298_3909747_+	NADP-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_001087606.1\|3909760_3911041_+	4-aminobutyrate--2-oxoglutarate transaminase	A0A1V0SKB7	Klosneuvirus	2.4e-33	30.1
WP_001344737.1\|3911351_3912752_+	GABA permease	NA	NA	NA	NA
WP_000156811.1\|3912772_3913435_+	DNA-binding transcriptional regulator CsiR	NA	NA	NA	NA
WP_000522424.1\|3913435_3913885_-	potassium binding protein Kbp	A0A090DBR9	Clostridium_phage	2.0e-06	39.5
WP_000508177.1\|3913968_3914127_-	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_000137280.1\|3914309_3914609_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001229468.1\|3914618_3915143_+	thiosulfate sulfurtransferase YgaP	NA	NA	NA	NA
WP_000115383.1\|3915189_3915594_-	DNA-binding protein StpA	NA	NA	NA	NA
WP_000492649.1\|3916261_3916711_+	L-alanine exporter AlaE	NA	NA	NA	NA
WP_000281320.1\|3916747_3917092_-	YgaC family protein	NA	NA	NA	NA
WP_001295174.1\|3917243_3917573_+	DUF883 domain-containing protein	NA	NA	NA	NA
WP_001223219.1\|3917820_3918066_+	glutaredoxin-like protein NrdH	Q5K5J3	Oenococcus_phage	4.1e-06	35.3
WP_000080947.1\|3918062_3918473_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	4.6e-18	44.4
WP_000246506.1\|3918445_3920590_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	9.3e-195	48.0
WP_000777939.1\|3920599_3921559_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	5.9e-133	71.5
WP_000985494.1\|3921913_3923116_+	glycine betaine/L-proline ABC transporter ATP-binding protein ProV	G3M9Y6	Bacillus_virus	4.9e-28	39.4
WP_000774994.1\|3923108_3924173_+	glycine betaine/L-proline ABC transporter permease ProW	NA	NA	NA	NA
WP_001216521.1\|3924230_3925223_+	glycine betaine/L-proline ABC transporter substrate-binding protein ProX	NA	NA	NA	NA
WP_000165722.1\|3925414_3926599_+	MFS transporter	NA	NA	NA	NA
WP_000445658.1\|3926722_3927460_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_000119771.1\|3927449_3927785_+	L-valine transporter subunit YgaH	NA	NA	NA	NA
WP_000378442.1\|3927875_3928406_+	multidrug efflux transporter EmrAB transcriptional repressor EmrR	NA	NA	NA	NA
WP_001295175.1\|3928532_3929705_+	multidrug efflux MFS transporter periplasmic adaptor subunit EmrA	NA	NA	NA	NA
WP_001295176.1\|3929721_3931260_+	multidrug efflux MFS transporter permease subunit EmrB	NA	NA	NA	NA
WP_001130207.1\|3931323_3931839_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_000611802.1\|3931988_3933545_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_001287457.1\|3933617_3934046_-	DedA family protein	NA	NA	NA	NA
WP_000273309.1\|3934042_3934609_-	fructose-1-phosphate/6-phosphogluconate phosphatase	NA	NA	NA	NA
WP_000906486.1\|3935932_3936118_-	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	4.9e-12	66.7
WP_000047176.1\|3936352_3938983_-\|tRNA	alanine--tRNA ligase	A0A2K9L1X7	Tupanvirus	5.5e-80	38.6

DBSCAN-SWA_17

3975978 : 3983118

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001272924.1\|3975978_3978540_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6
WP_001141347.1\|3978645_3979302_+	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	5.6e-50	47.2
WP_001297141.1\|3979352_3980120_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_000847985.1\|3980315_3981224_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_000590389.1\|3981220_3982483_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	3.7e-135	61.4
WP_001278994.1\|3982479_3983118_+	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP027223

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 7549

Escherichia_phage(57.14%)

head,holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106898678.1\|0_947_-\|head	internal head protein	A0A1B0V7H1	Salmonella_phage	3.1e-158	94.0
WP_001345482.1\|948_1551_-	hypothetical protein	Q1MVM6	Enterobacteria_phage	5.4e-100	100.0
WP_000580776.1\|1537_1981_-	hypothetical protein	A0A077SK09	Escherichia_phage	1.3e-82	100.0
WP_000887652.1\|1977_2307_-\|holin	holin	Q37876	Escherichia_phage	1.3e-52	100.0
WP_024177048.1\|2197_2572_+	hypothetical protein	A0A077SL44	Escherichia_phage	1.0e-24	63.1
WP_122993347.1\|3060_3633_+	serine acetyltransferase	NA	NA	NA	NA
WP_106898679.1\|3676_4255_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.9e-95	88.5
WP_001286326.1\|7114_7549_-	hypothetical protein	A0A077SLL3	Escherichia_phage	3.3e-75	100.0

DBSCAN-SWA_2

13704 : 35014

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001697757.1\|13704_14586_-	hypothetical protein	Q71TC9	Escherichia_phage	1.1e-173	99.3
WP_000523978.1\|14600_15212_-	hypothetical protein	A0A077SLH8	Escherichia_phage	5.8e-110	100.0
WP_072101257.1\|15222_15468_-	hypothetical protein	Q1MVL0	Enterobacteria_phage	3.4e-37	100.0
WP_106898680.1\|15497_15788_-	hypothetical protein	Q1MVL0	Enterobacteria_phage	1.1e-39	100.0
WP_000846124.1\|15846_16116_-	hypothetical protein	NA	NA	NA	NA
WP_000120526.1\|16374_17049_-	hypothetical protein	Q71TC4	Escherichia_phage	6.8e-19	94.0
WP_016231365.1\|17449_17671_+	host cell division inhibitor Icd-like protein	Q38557	Escherichia_phage	8.1e-38	97.3
WP_000743174.1\|17667_18711_+	phage antirepressor Ant	Q71TN2	Escherichia_phage	1.1e-172	93.4
WP_001187871.1\|18875_19676_+	protein kilA	Q1MVK4	Enterobacteria_phage	5.4e-148	99.6
WP_106898681.1\|19705_20551_+	Replication protein repL	Q1MVK3	Enterobacteria_phage	3.8e-152	98.9
WP_001426344.1\|20601_20847_+	hypothetical protein	A0A1B0VDM5	Salmonella_phage	3.5e-13	45.0
WP_001313475.1\|21028_21184_+	type I toxin-antitoxin system toxin HokD	A0A1I9LJU7	Stx_converting_phage	1.0e-15	92.2
WP_001339188.1\|21300_21555_-	hypothetical protein	Q71TM5	Escherichia_phage	5.9e-40	98.8
WP_000041774.1\|22436_23252_-	hypothetical protein	A0A1B0V835	Salmonella_phage	9.8e-113	99.3
WP_000085155.1\|23261_24851_-	hypothetical protein	A0A1B0V7E4	Salmonella_phage	6.2e-305	99.2
WP_000067713.1\|24911_26618_-	hypothetical protein	Q71TM1	Escherichia_phage	0.0e+00	99.8
WP_000038868.1\|26842_27844_-	ParB/RepB/Spo0J family partition protein	Q38420	Escherichia_phage	3.7e-178	99.7
WP_000888906.1\|30330_31215_-	RepB family plasmid replication initiator protein	A0A1B0VDL5	Salmonella_phage	1.4e-160	99.7
WP_001281116.1\|31548_31941_-	hypothetical protein	A0A077SLJ1	Escherichia_phage	2.0e-71	99.2
WP_000336812.1\|31952_32093_-	hypothetical protein	Q71TL6	Escherichia_phage	6.3e-20	100.0
WP_000007769.1\|32118_32541_-	hypothetical protein	A0A1B0VCB0	Salmonella_phage	2.7e-58	100.0
WP_000890203.1\|32580_33369_-	hypothetical protein	A0A1B0V830	Salmonella_phage	9.2e-108	89.3
WP_001369296.1\|33377_33557_-	hypothetical protein	A0A1B0V758	Salmonella_phage	6.8e-27	98.3
WP_001177859.1\|33831_34116_+	hypothetical protein	Q71TA2	Escherichia_phage	1.7e-48	98.9
WP_000472523.1\|34108_35014_+	recombination-associated protein RdgC	A0A077SK17	Escherichia_phage	5.9e-159	99.3

DBSCAN-SWA_3

40306 : 72187

Escherichia_phage(75.61%)

transposase,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000751806.1\|40306_41134_+	hypothetical protein	A0A077SLJ6	Escherichia_phage	2.8e-131	99.6
WP_001276599.1\|41517_42882_+	replicative DNA helicase	A0A077SK18	Escherichia_phage	2.1e-253	100.0
WP_001198661.1\|42881_43880_+	hypothetical protein	Q71TK3	Escherichia_phage	9.0e-193	98.8
WP_000245706.1\|44259_44481_+	host cell division inhibitor Icd-like protein	Q38557	Escherichia_phage	2.1e-30	82.2
WP_000535208.1\|45581_46214_-	hypothetical protein	Q1MVH8	Enterobacteria_phage	9.0e-90	100.0
WP_085948178.1\|46862_48075_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000602717.1\|48536_49322_-	hypothetical protein	Q71T90	Escherichia_phage	4.6e-144	99.6
WP_000896801.1\|49308_50037_-	hypothetical protein	A0A077SK19	Escherichia_phage	9.3e-139	100.0
WP_000235786.1\|51268_51646_-	hypothetical protein	Q38620	Escherichia_phage	2.2e-67	100.0
WP_000840930.1\|51792_52038_+	hypothetical protein	A0A1B0VDU5	Salmonella_phage	1.5e-40	100.0
WP_024224109.1\|52040_52619_+	norphogenetic protein	Q71T85	Escherichia_phage	9.8e-99	92.2
WP_001561105.1\|52685_52841_+	hypothetical protein	Q71TJ4	Escherichia_phage	2.0e-19	98.0
WP_000484116.1\|53342_53969_+	norphogenetic protein	Q1MVG8	Enterobacteria_phage	2.1e-123	100.0
WP_032353941.1\|53965_54643_+	serine/threonine protein phosphatase	Q71TJ1	Escherichia_phage	1.0e-131	98.2
WP_032271828.1\|54639_55341_+	hypothetical protein	A0A077SLK3	Escherichia_phage	1.1e-141	98.3
WP_023442324.1\|55642_56905_+	hypothetical protein	A0A1B0V7L1	Salmonella_phage	1.7e-233	99.3
WP_000021755.1\|56977_57484_+	hypothetical protein	A0A077SK53	Escherichia_phage	5.4e-93	98.8
WP_000675643.1\|57678_58260_+	hypothetical protein	A0A077SLQ8	Escherichia_phage	2.0e-112	100.0
WP_023442323.1\|58252_58519_+	hypothetical protein	Q1MVG1	Enterobacteria_phage	4.5e-43	98.8
WP_023442322.1\|58505_59207_+	ead/Ea22-like family protein	A0A0U2QW67	Escherichia_phage	7.0e-51	55.8
WP_001018057.1\|59203_59494_+	DUF4752 family protein	A0A2I6TCB0	Escherichia_phage	1.2e-36	82.3
WP_000403776.1\|60160_60520_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	8.0e-59	99.2
WP_000935430.1\|60565_60778_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	2.2e-32	88.6
WP_000797281.1\|60840_61029_+	hypothetical protein	A0A1I9LJM4	Stx_converting_phage	2.8e-31	100.0
WP_000951706.1\|61030_61240_+	hypothetical protein	A0A077SL56	Escherichia_phage	4.2e-36	100.0
WP_032271829.1\|61236_62067_+	DUF551 domain-containing protein	A0A077SK54	Escherichia_phage	1.3e-125	78.2
WP_024224112.1\|62063_62324_+	hypothetical protein	A0A077SLR0	Escherichia_phage	9.3e-41	96.5
WP_000516537.1\|62409_62643_+	hypothetical protein	A0A1B0V7L5	Salmonella_phage	1.6e-36	97.4
WP_000269004.1\|62821_63115_+	hypothetical protein	A0A077SK23	Escherichia_phage	3.1e-45	92.8
WP_024224113.1\|63121_63496_+	hypothetical protein	A0A077SL57	Escherichia_phage	7.0e-66	96.0
WP_000057453.1\|63477_64128_+	hypothetical protein	A0A077SK55	Escherichia_phage	2.1e-97	94.5
WP_001408981.1\|64400_64661_+	hypothetical protein	NA	NA	NA	NA
WP_024224114.1\|64976_65228_+	DNA polymerase III subunit theta	Q71T70	Escherichia_phage	1.4e-38	97.6
WP_052921651.1\|65234_65807_-	hypothetical protein	Q1MVE8	Enterobacteria_phage	6.9e-105	96.8
WP_024224146.1\|65982_66372_+	DNA repair protein	Q1MVE7	Enterobacteria_phage	4.1e-69	98.4
WP_001216044.1\|66666_67047_+	type II toxin-antitoxin system death-on-curing family toxin	Q71T66	Escherichia_phage	2.8e-62	99.2
WP_024224144.1\|67051_67231_+	hypothetical protein	Q71TH5	Escherichia_phage	2.3e-22	96.6
WP_023442316.1\|67258_68302_+	DUF968 domain-containing protein	A0A077SLM1	Escherichia_phage	4.8e-205	99.1
WP_001326849.1\|68390_68843_+	late promoter-activating protein	Q71T63	Escherichia_phage	3.0e-79	100.0
WP_106898683.1\|68928_70122_+\|terminase	terminase	A0A077SL59	Escherichia_phage	2.3e-179	99.5
WP_000124159.1\|70121_71606_+	hypothetical protein	Q5QBP2	Enterobacteria_phage	4.3e-292	99.8
WP_071527722.1\|71827_71947_+	hypothetical protein	NA	NA	NA	NA
WP_001361625.1\|71965_72187_+	host cell division inhibitor Icd-like protein	Q38557	Escherichia_phage	6.0e-25	81.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP027221

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP027223

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection