CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP027582	Escherichia coli strain 2013C-4538 chromosome, complete genome	8 crisprs	c2c9_V-U4,DEDDh,DinG,cas3,PrimPol,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2	1	12	22	0
NZ_CP027583	Escherichia coli strain 2013C-4538 plasmid unnamed	0 crisprs	NA	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP027582_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_1

1189593-1189716

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP027582_1

>merge|NZ_CP027582|1|1189593-1189716|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP027582|1|1|1189593-1189716|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_000716921.1\|1187422_1189027_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP027582.1\|WP_000007283.1\|1200182_1200764_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP027582.1\|WP_000102278.1\|1198612_1198702_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP027582.1\|WP_000701040.1\|1198867_1200037_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP027582.1\|WP_000212657.1\|1189152_1189458_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP027582.1\|WP_000534296.1\|1190030_1191287_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP027582.1\|WP_001295403.1\|1179046_1180459_-\|pyruvate-kinase-PykF	unknown	unknown	gnl\|CDD\|181699
NZ_CP027582.1\|WP_001070230.1\|1181680_1182307_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP027582.1\|WP_000190982.1\|1197288_1198314_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP027582.1\|WP_000528342.1\|1181015_1181225_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
NZ_CP027582.1\|WP_001310861.1\|1185144_1185813_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP027582.1\|WP_000504352.1\|1184433_1185081_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP027582.1\|WP_001174940.1\|1191327_1192701_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP027582.1\|WP_000098896.1\|1193596_1194745_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP027582.1\|WP_000587560.1\|1186598_1187411_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP027582.1\|WP_001273518.1\|1182327_1184430_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP027582.1\|WP_000269501.1\|1196359_1197292_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP027582.1\|WP_001182363.1\|1195035_1196247_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP027582.1\|WP_000493947.1\|1192915_1193557_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP027582.1\|WP_001069997.1\|1185809_1186595_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_000716921.1\|1187422_1189027_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP027582.1\|WP_000007283.1\|1200182_1200764_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP027582.1\|WP_000701040.1\|1198867_1200037_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
NZ_CP027582.1\|WP_000212657.1\|1189152_1189458_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
NZ_CP027582.1\|WP_000534296.1\|1190030_1191287_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP027582.1\|WP_001295403.1\|1179046_1180459_-\|pyruvate-kinase-PykF	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP027582.1\|WP_001070230.1\|1181680_1182307_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP027582.1\|WP_000190982.1\|1197288_1198314_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP027582.1\|WP_000528342.1\|1181015_1181225_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
NZ_CP027582.1\|WP_001310861.1\|1185144_1185813_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	2.09652e-76
NZ_CP027582.1\|WP_000504352.1\|1184433_1185081_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	2.81741e-122
NZ_CP027582.1\|WP_001174940.1\|1191327_1192701_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP027582.1\|WP_000098896.1\|1193596_1194745_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP027582.1\|WP_000587560.1\|1186598_1187411_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.20825e-175
NZ_CP027582.1\|WP_001273518.1\|1182327_1184430_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP027582.1\|WP_000269501.1\|1196359_1197292_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP027582.1\|WP_001182363.1\|1195035_1196247_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP027582.1\|WP_000493947.1\|1192915_1193557_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP027582.1\|WP_001069997.1\|1185809_1186595_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.33298e-163

>NZ_CP027582.1|WP_000212657.1|1189152_1189458_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP027582.1|WP_000716921.1|1187422_1189027_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDIGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP027582.1|WP_000587560.1|1186598_1187411_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC
>NZ_CP027582.1|WP_001069997.1|1185809_1186595_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP027582.1|WP_001310861.1|1185144_1185813_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP027582.1|WP_000504352.1|1184433_1185081_+|YdhW-family-putative-oxidoreductase-system-protein
MGEMNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP027582.1|WP_001273518.1|1182327_1184430_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIHWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>NZ_CP027582.1|WP_001070230.1|1181680_1182307_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP027582.1|WP_000528342.1|1181015_1181225_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP027582.1|WP_001295403.1|1179046_1180459_-|pyruvate-kinase-PykF
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP027582.1|WP_000534296.1|1190030_1191287_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFSVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIRVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP027582.1|WP_001174940.1|1191327_1192701_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
>NZ_CP027582.1|WP_000493947.1|1192915_1193557_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP027582.1|WP_000098896.1|1193596_1194745_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP027582.1|WP_001182363.1|1195035_1196247_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>NZ_CP027582.1|WP_000269501.1|1196359_1197292_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP027582.1|WP_000190982.1|1197288_1198314_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP027582.1|WP_000102278.1|1198612_1198702_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP027582.1|WP_000701040.1|1198867_1200037_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP027582.1|WP_000007283.1|1200182_1200764_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

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Crispr_ID: NZ_CP027582_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_2

1856218-1856421

Orphan

Consensus_repeat	Method
TCTCCCCACTTTTACTCCCCACTTTTT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP027582_2

>merge|NZ_CP027582|2|1856218-1856421|PILER-CR
TCCCCACTACTCCCCACTTTTGCTCCCCACTTTTTGAAATTACCCACCGTCTCCCCACCTCTTTTTTTTTGTGATTCTAACGTGATGTTTTTCAATATATTTTTTACTCCCCACTTTTTTGGGTATATACAGGTGGGAAAGTGGGCAATTATGTTTCAATTTTGTTAAATTCCCCACTCTCCCCACTTTTACTCCCCACTTTTT

>NZ_CP027582|2|1|1856218-1856421|PILER-CR
TCCCCACTACTCCCCACTTTTGCTCCCCACTTTTTG	AAATTACCCACCGTCTCCCCACCTCTTTTTTTTTGTGATTCTAACGTGATGTTTTTCAATATATT
TTTTACTCCCCACTTTTTTGGGTATATACAGGTGGG	AAAGTGGGCAATTATGTTTCAATTTTGTTAAATTCCCCACTCTCCCCACTTTTACTCC
CCACTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_000551751.1\|1858567_1858933_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000085269.1\|1861249_1862479_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271182
NZ_CP027582.1\|WP_001368652.1\|1855663_1855852_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000504047.1\|1852547_1853120_-\|HK97-family-phage-prohead-protease	unknown	unknown	gnl\|CDD\|226263
NZ_CP027582.1\|WP_000134114.1\|1850706_1851003_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|130623
NZ_CP027582.1\|WP_001204967.1\|1858118_1858352_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_001398592.1\|1851334_1852510_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|227039
NZ_CP027582.1\|WP_000336141.1\|1858925_1859150_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000126670.1\|1855243_1855654_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|239942
NZ_CP027582.1\|WP_001502337.1\|1859366_1860644_-\|host-cell-division-inhibitor-Icd-like-protein	unknown	unknown	gnl\|CDD\|214989
NZ_CP027582.1\|WP_000953274.1\|1860696_1860885_-\|AlpA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225848
NZ_CP027582.1\|WP_001020669.1\|1850999_1851338_-\|phage-head-closure-protein	unknown	unknown	gnl\|CDD\|227901
NZ_CP027582.1\|WP_000456506.1\|1862727_1863849_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|225406
NZ_CP027582.1\|WP_001204070.1\|1858353_1858575_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_001132080.1\|1854608_1854833_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000770163.1\|1857813_1858113_-\|DUF4222-domain-containing-protein	unknown	unknown	gnl\|CDD\|372855
NZ_CP027582.1\|WP_000076671.1\|1859139_1859370_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000233311.1\|1854958_1855231_-\|PerC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|310570
NZ_CP027582.1\|WP_001137338.1\|1853159_1854317_-\|phage-major-capsid-protein	unknown	unknown	gnl\|CDD\|227000
NZ_CP027582.1\|WP_001080642.1\|1855965_1856217_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_000085269.1\|1861249_1862479_-\|site-specific-integrase	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.85678e-49
NZ_CP027582.1\|WP_000504047.1\|1852547_1853120_-\|HK97-family-phage-prohead-protease	gnl\|CDD\|226263	COG3740, COG3740, Phage head maturation protease [General function prediction only].	1.36228e-77
NZ_CP027582.1\|WP_000134114.1\|1850706_1851003_-\|hypothetical-protein	gnl\|CDD\|130623	TIGR01560, phage-related_hypothetical_protein, uncharacterized phage protein (possible DNA packaging). This model describes a small (~ 100 amino acids) protein found in phage and in putative prophage regions of a number of bacterial genomes. Members have been annotated in some cases as a possible DNA packaging protein, but the source of this annotation was not traced during construction of this model. [Mobile and extrachromosomal element functions, Prophage functions].	7.0294e-39
NZ_CP027582.1\|WP_001398592.1\|1851334_1852510_-\|phage-portal-protein	gnl\|CDD\|227039	COG4695, COG4695, Phage-related protein [Function unknown].	1.09875e-148
NZ_CP027582.1\|WP_000456506.1\|1862727_1863849_+\|cupin-domain-containing-protein	gnl\|CDD\|225406	COG2850, COG2850, Uncharacterized conserved protein [Function unknown].	0
NZ_CP027582.1\|WP_000126670.1\|1855243_1855654_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	3.49806e-23
NZ_CP027582.1\|WP_001502337.1\|1859366_1860644_-\|host-cell-division-inhibitor-Icd-like-protein	gnl\|CDD\|214989	smart01040, Bro-N, BRO family, N-terminal domain. This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.	0.000513266
NZ_CP027582.1\|WP_001020669.1\|1850999_1851338_-\|phage-head-closure-protein	gnl\|CDD\|227901	COG5614, COG5614, Bacteriophage head-tail adaptor [General function prediction only].	1.78157e-42
NZ_CP027582.1\|WP_000233311.1\|1854958_1855231_-\|PerC-family-transcriptional-regulator	gnl\|CDD\|310570	pfam06069, PerC, PerC transcriptional activator. PerC is a transcriptional activator of EaeA/BfpA expression in enteropathogenic bacteria.	5.90034e-44
NZ_CP027582.1\|WP_000770163.1\|1857813_1858113_-\|DUF4222-domain-containing-protein	gnl\|CDD\|372855	pfam13973, DUF4222, Domain of unknown function (DUF4222). This short protein is likely to be of phage origin. For example it is found in the Enterobacteria phage YYZ-2008. It is largely found in enteric bacteria. The molecular function of this protein is unknown.	1.79974e-21
NZ_CP027582.1\|WP_001137338.1\|1853159_1854317_-\|phage-major-capsid-protein	gnl\|CDD\|227000	COG4653, COG4653, Predicted phage phi-C31 gp36 major capsid-like protein [General function prediction only].	1.06423e-164
NZ_CP027582.1\|WP_000953274.1\|1860696_1860885_-\|AlpA-family-transcriptional-regulator	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	5.02435e-22

>NZ_CP027582.1|WP_001080642.1|1855965_1856217_-|hypothetical-protein
MNRKTRDKTAPKYKALDMTELSLKVAIRTIDRHVGEGYAKEHPDLISAFMTTAAANFATLTEREIAEAEQVTTINVKTGEVES
>NZ_CP027582.1|WP_001368652.1|1855663_1855852_-|hypothetical-protein
MASWALCVLSYPDRDVYQDILPVISTDKGMKPVDIKNMGFQCVMLTEKMMEEMKKNNAGSLH
>NZ_CP027582.1|WP_000126670.1|1855243_1855654_-|single-stranded-DNA-binding-protein
MTAQIAAYGRLVDDPLVKQSSKGTPMTLARMAVSLPCSQAHDGQATLWLSVIAFGKQADFLAKHQKGDVASVSGTMQVSQWTGQNGETRQGYQVIADSVISARAARPGGNRRKTTGTQGNQPPAGGDDPYGDDIPF
>NZ_CP027582.1|WP_000233311.1|1854958_1855231_-|PerC-family-transcriptional-regulator
MVHDRIAEELEAKGFYRRASARWGEVMQLVETDKERHHITMRRLECCRKAQRPPEPPDNYGDLKKAVDRTYAEMGIDGAGDEIWRNYQDS
>NZ_CP027582.1|WP_001132080.1|1854608_1854833_-|hypothetical-protein
MPMKFDEILKQRDKYHADNMETMSINDYRAFLETGALIEKDQHGFVRCALSGEMLAVNPEQIDALIEFLKGIRD
>NZ_CP027582.1|WP_001137338.1|1853159_1854317_-|phage-major-capsid-protein
MPRIIELRQQKTAIKNQMRDMLENAEKENRSLNDAEGAKFDELRAKAESLDKDISRLEAIADEERSKPGKSSQTTDPAELRNYILTGETRALSTGVPADGGYTVIPELNTEIMRMLADESTMRRICTVKKISSNEFKQLVSAGGATVNHGEEGKAREQTSPPQINEVSIKLYPVYAYPRTTQEIVDFSDVDILSWLTGEIGDTFTETEESDLVVGDGDKKAKGFLSVPRAEKNDKERDFGTLQVIKPSESLAWTSADPLIDLKFALRKKYRKNAVWVVNSTTAAKLQKVKNANGDYIWRDRLQAGDPDTLLGLPVEYLEFMPDNVIALGDFKRGYYIVDHETGVRTRPDNLTEPGFIKIFTQKYLGGGVVDSNAIKILELPQDDD
>NZ_CP027582.1|WP_000504047.1|1852547_1853120_-|HK97-family-phage-prohead-protease
MGEKIMKSMEIRSSEITTSASNTLTGYVVRWDKLSELLWGEFYEKFQRGAFTEWLAAGNDVRGLYEHDHSMLLGRTRSGTLKLEEDETGLRFELTPPDTSTGRDVIELVKRGDISGMSFGFRSRKDVWDTTTDPCVRTVLVAELYEITVTSVPAYPDSGVELARRSLYEQHPEKMPRADNRRWWADLAGV
>NZ_CP027582.1|WP_001398592.1|1851334_1852510_-|phage-portal-protein
MTLDEFMALAGTSNTGAGEYVSSGTAESLPAVMNAVTVISEAVATMPCYLYLVRNEKGKEAREWLDSHPVDHILNERPNAWQTPYQFKRMMIRHCLLNGNAYAVIQWGRDGFPVALHPYPPQSVNVEQTGEHNWRYCITDAYTGNTRNYLPWEVLHLRYSTDDGFMGRSPVTICRESLGLGLAQQRHGASVMRDGMMAAGVITSGEWLDGVKGKQALAALERYKGARNAGKTPILEGGMSYQQLGMSNQDAEWLASRRFTIEDIARMFNVSPIFLQEYSNSTYSNFSEASRAFLTMTMRPWLANFEQQIKNALLVASPVPGIRYQVEFDSADLLRATPGERFATYERGIKSGVMCPNEAREREGLSPRDGGDEFSQAWKQEVKISEGEKPE
>NZ_CP027582.1|WP_001020669.1|1850999_1851338_-|phage-head-closure-protein
MNIGRLRDRVTIQTLKQTRDITGEILETWEDGHTLWASVNMISSKEAISSGAELAIGTVRIWIRYRKDINATSRIKVNTGPLAGRVLNIIGQPLPDAARTRLEILCREGAEK
>NZ_CP027582.1|WP_000134114.1|1850706_1851003_-|hypothetical-protein
MTEELITLEEVKLHCRIDGDEEDQLISGYIAASLEACQIHIGRRFDDGLEFTPAIKIGCMMFIAHLYENRQLVADNAKTRVPMTIGALWTAYRDVGVY
>NZ_CP027582.1|WP_000770163.1|1857813_1858113_-|DUF4222-domain-containing-protein
MKLKYSGLTASGNTHPKFTRGDIYRDQYGGTVMIKGVAGRCVTYRREGYEYDCVMPVYQFRRDFSLVQTAPHNVPTSNARARANIQKLKTMINGFRGKK
>NZ_CP027582.1|WP_001204967.1|1858118_1858352_-|hypothetical-protein
MRDIYHETIDRAFSALAYAEGMYEILRIWLETLGDNERDKQKSRIVTALITLLEPVIMELQEIDLLHDIYKEQHTGE
>NZ_CP027582.1|WP_001204070.1|1858353_1858575_-|hypothetical-protein
MRDDRFNSLKQEFSGVPDDAADALSSISEIMRVAFFFLCTDEHRDTGLNILDIAANYADFVTEAVLRKTTDGD
>NZ_CP027582.1|WP_000551751.1|1858567_1858933_-|hypothetical-protein
MHNLSISDLNSIQFDEKFTGQLLVNVENGRIVRNYHLPDGAIAGSVEALLELAERARLIKPSTSHHDDDLHFTGCMVSHYENGVEVSCERLRDDCCFGTLPEFIELLTSCGYQVIQGGKHA
>NZ_CP027582.1|WP_000336141.1|1858925_1859150_-|hypothetical-protein
MCNKTTPDAAAAALTTLMHALIDISVIADRAHKHAARESECIFHYLTFVQLKADQALDKAGKIIMADVQEVHHA
>NZ_CP027582.1|WP_000076671.1|1859139_1859370_-|hypothetical-protein
MSQEITLQQAAERAHQIEVICALAEDYPGMMTDSESGAIIGLLKRLSGEVCVFLSDEQERRTLISNEKKCGGVHVQ
>NZ_CP027582.1|WP_001502337.1|1859366_1860644_-|host-cell-division-inhibitor-Icd-like-protein
MNTGYSPEQGRGFVRPEKQNLQNFAEIIPVISGLTGGSETNIVNARALQMFDDKKGVNLTYTPDGNQNMSIISESGFYKLIKTKSAPLPERLCEQLTYCAKNESEQWDYINHVEKRHNCRITGKTKATRYGGPSTQATRYPQRMSIANNATFAAGGQCNQSGSVRCHTCNERFSLYSLRNCSRAKAHGANLSDSCSIFLRRLFRAGDNVLVNSLSVIVLSCIAMRRSYSHHGAGDGYSCSLALRRWRRLISPLTAVTINCALLSPSSKFFSKSATTSCGNLAFNCCDLLFVEPVAITESSLSWCDSVYTKKISEKDLKCDSLTDRLKTNGAMHQTTTPRSGGTHAGRLTTNDSESIEVAMRNHTIHPQGRDSHNLNKYIWRFIALSTAQPRVITIEATSEQEARQQSPAGCVMVFAARIRQGVGL
>NZ_CP027582.1|WP_000953274.1|1860696_1860885_-|AlpA-family-transcriptional-regulator
MLSTDRFIREKECQQLTGLSRSCRYRLEKAGQFPSRRKLGGRSVGWSLSEVLAWKDSCEAVH
>NZ_CP027582.1|WP_000085269.1|1861249_1862479_-|site-specific-integrase
MSRALNKLSDTQLRKINGTPAQKTAFLNDGGNLSVRHSTSGLLTWYFTYRAGTGRGARPERIKLGNYPDLSLKAAREKAAQCRAWLAEGKNPRHEMNYTVQKALKPVTVGDALTYWLESYVKENRVDYAALKKRLNNHVIQHIGAMPLDKCELRHWLACFDQVAKRTPVTAGFLLQTCKQALKFCRRRRYAISNVLDDMSVADVGKKPDISERVLSTKELGELLQALDKKIFSPYYVALIRLLIVFGCRTVELRLSEISEWDFTEMLWTVPKEHSKTKVAIFRPIPEAILPFVTQLVEQNRHTGLLLGEVKQETSVSQYGRLAHRRLKHPHWSLHDIRRTFTTMLNDLGVDPHVVEQLTGHQMPGMQRVYNHSRYLDAKRDALDMWTERLGILAGTHENVTTLPIAREI
>NZ_CP027582.1|WP_000456506.1|1862727_1863849_+|cupin-domain-containing-protein
MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLLQVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALDALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG

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Crispr_ID: NZ_CP027582_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_3

2138289-2138380

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP027582_3

>merge|NZ_CP027582|3|2138289-2138380|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP027582|3|2|2138289-2138380|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTACCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_001143120.1\|2139420_2139648_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP027582.1\|WP_000979516.1\|2127539_2127749_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000209869.1\|2144055_2144655_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP027582.1\|WP_001240628.1\|2136846_2138175_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP027582.1\|WP_021534122.1\|2134526_2134913_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677
NZ_CP027582.1\|WP_001044313.1\|2139685_2140927_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP027582.1\|WP_001001171.1\|2135730_2136321_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP027582.1\|WP_001062101.1\|2144651_2147198_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP027582.1\|WP_001297176.1\|2132731_2133823_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP027582.1\|WP_001028095.1\|2136331_2136826_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NZ_CP027582.1\|WP_001341463.1\|2127803_2131766_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP027582.1\|WP_001151437.1\|2138803_2139400_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP027582.1\|WP_000097601.1\|2141218_2142478_-\|YccE-family-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP027582.1\|WP_000420629.1\|2142737_2143658_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP027582.1\|WP_001341462.1\|2134920_2135721_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP027582.1\|WP_000191700.1\|2131805_2132444_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP027582.1\|WP_001120112.1\|2148499_2149192_+\|two-component-system-response-regulator-TorR	unknown	unknown	gnl\|CDD\|182711
NZ_CP027582.1\|WP_000024561.1\|2143657_2143963_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP027582.1\|WP_001230242.1\|2147197_2148370_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992
NZ_CP027582.1\|WP_001307708.1\|2133822_2134515_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_001143120.1\|2139420_2139648_+\|hypothetical-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP027582.1\|WP_001120112.1\|2148499_2149192_+\|two-component-system-response-regulator-TorR	gnl\|CDD\|182711	PRK10766, PRK10766, two-component system response regulator TorR.	5.89892e-138
NZ_CP027582.1\|WP_000209869.1\|2144055_2144655_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	5.28244e-84
NZ_CP027582.1\|WP_001240628.1\|2136846_2138175_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP027582.1\|WP_021534122.1\|2134526_2134913_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	3.32185e-83
NZ_CP027582.1\|WP_001044313.1\|2139685_2140927_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP027582.1\|WP_001001171.1\|2135730_2136321_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	1.00331e-130
NZ_CP027582.1\|WP_001062101.1\|2144651_2147198_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP027582.1\|WP_001297176.1\|2132731_2133823_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP027582.1\|WP_001028095.1\|2136331_2136826_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	3.76111e-106
NZ_CP027582.1\|WP_001341463.1\|2127803_2131766_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP027582.1\|WP_001151437.1\|2138803_2139400_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	8.51484e-133
NZ_CP027582.1\|WP_000097601.1\|2141218_2142478_-\|YccE-family-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP027582.1\|WP_000420629.1\|2142737_2143658_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP027582.1\|WP_001341462.1\|2134920_2135721_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	3.3907e-141
NZ_CP027582.1\|WP_000191700.1\|2131805_2132444_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	1.12845e-153
NZ_CP027582.1\|WP_000024561.1\|2143657_2143963_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	2.74017e-64
NZ_CP027582.1\|WP_001230242.1\|2147197_2148370_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0
NZ_CP027582.1\|WP_001307708.1\|2133822_2134515_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	5.84226e-169

>NZ_CP027582.1|WP_001240628.1|2136846_2138175_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPYERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNLLGLGKAVDFTLVSHAAWFGLPHFSTPAFNSQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP
>NZ_CP027582.1|WP_001028095.1|2136331_2136826_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
>NZ_CP027582.1|WP_001001171.1|2135730_2136321_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFAGSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
>NZ_CP027582.1|WP_001341462.1|2134920_2135721_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADTPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP027582.1|WP_021534122.1|2134526_2134913_+|pyrimidine-utilization-protein-C
MPKFVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLEIIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP027582.1|WP_001307708.1|2133822_2134515_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>NZ_CP027582.1|WP_001297176.1|2132731_2133823_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP027582.1|WP_000191700.1|2131805_2132444_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEIFFNQTVENVQRIIIEGIRPR
>NZ_CP027582.1|WP_001341463.1|2127803_2131766_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPLSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP027582.1|WP_000979516.1|2127539_2127749_-|hypothetical-protein
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NZ_CP027582.1|WP_001151437.1|2138803_2139400_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP027582.1|WP_001143120.1|2139420_2139648_+|hypothetical-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP027582.1|WP_001044313.1|2139685_2140927_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAATVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAQQGMVKSGECPPPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDANGFCPMDKFDSVLNEAVK
>NZ_CP027582.1|WP_000097601.1|2141218_2142478_-|YccE-family-protein
MSSNIHGISCTANNYLKQAWNNIKNEHEKNQKYSITLFENTLVCFMRLYKEIRRQKAEDYIPCLECDSLEKEFEEMQNDNDLSLFLRTLRTNDTETYSGVSEGITYTIQYVRDIDIVRVSLPGRGSESITDFKGYYWYGFMEYIENINACDDVFSEYCLDDENMSIQPEWINTPGISDLDTGIDLSGISFIQSEINKTYGLKYAPVDGDGYCLLRAILVLKEHEYSWALGSHKTQKQVYEEFIKIVDKQTIEALVDTAFNDLREDVKTLFGVNLQSDNKIQGQGGFLSWSFLSFKKEFIDSCLNDKKCILHLPEFIFNDNKARLVLDTDPEQKVNEVKNFLTALSDSICSLFIVNGNVASISLGNESFSTDDDLEYGYLINTGNHYDVYLPPELFAQAYELNNKERNAQIDFLTRYAIY
>NZ_CP027582.1|WP_000420629.1|2142737_2143658_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHSDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGHDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP027582.1|WP_000024561.1|2143657_2143963_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVTHP
>NZ_CP027582.1|WP_000209869.1|2144055_2144655_-|molecular-chaperone-TorD
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVVRCRQYDSFGFYAALSQLLLVLVESDHQNR
>NZ_CP027582.1|WP_001062101.1|2144651_2147198_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS
>NZ_CP027582.1|WP_001230242.1|2147197_2148370_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>NZ_CP027582.1|WP_001120112.1|2148499_2149192_+|two-component-system-response-regulator-TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC

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Crispr_ID: NZ_CP027582_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_4

2625414-2625558

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP027582_4

>merge|NZ_CP027582|4|2625414-2625558|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>NZ_CP027582|4|3|2625414-2625558|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_000104414.1\|2620750_2621368_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_001281774.1\|2622212_2622557_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000604034.1\|2634794_2635484_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_CP027582.1\|WP_001036475.1\|2628025_2629459_-\|anion-permease	unknown	unknown	gnl\|CDD\|279307
NZ_CP027582.1\|WP_000891685.1\|2633733_2634792_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP027582.1\|WP_000113001.1\|2635483_2636257_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NZ_CP027582.1\|WP_000891515.1\|2636422_2636572_-\|multidrug-efflux-pump-accessory-protein-AcrZ	unknown	unknown	gnl\|CDD\|371231
NZ_CP027582.1\|WP_000679972.1\|2630770_2631724_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
NZ_CP027582.1\|WP_000593936.1\|2625581_2627843_-\|hydratase	unknown	unknown	gnl\|CDD\|183125
NZ_CP027582.1\|WP_001091569.1\|2624064_2625348_+\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP027582.1\|WP_000213425.1\|2632914_2633733_+\|pyridoxal-phosphatase	unknown	unknown	gnl\|CDD\|182523
NZ_CP027582.1\|WP_012817743.1\|2621364_2621667_+\|restriction-alleviation-protein,-Lar-family	unknown	unknown	gnl\|CDD\|274704
NZ_CP027582.1\|WP_000723652.1\|2629534_2630587_-\|4-oxalomesaconate-tautomerase	unknown	unknown	gnl\|CDD\|380230
NZ_CP027582.1\|WP_032278566.1\|2621659_2621944_+\|ASCH-domain-containing-protein	unknown	unknown	gnl\|CDD\|214979
NZ_CP027582.1\|WP_032277527.1\|2631764_2632760_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
NZ_CP027582.1\|WP_000533654.1\|2622859_2623930_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271181
NZ_CP027582.1\|WP_001303849.1\|2622663_2622882_+\|excisionase	unknown	unknown	gnl\|CDD\|116439
NZ_CP027582.1\|WP_000812206.1\|2619637_2620195_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000034231.1\|2620191_2620749_+\|ead/Ea22-like-family-protein	unknown	unknown	gnl\|CDD\|379401
NZ_CP027582.1\|WP_000545733.1\|2622016_2622184_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_000604034.1\|2634794_2635484_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
NZ_CP027582.1\|WP_001036475.1\|2628025_2629459_-\|anion-permease	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
NZ_CP027582.1\|WP_000113001.1\|2635483_2636257_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
NZ_CP027582.1\|WP_000891515.1\|2636422_2636572_-\|multidrug-efflux-pump-accessory-protein-AcrZ	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17
NZ_CP027582.1\|WP_000891685.1\|2633733_2634792_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP027582.1\|WP_000593936.1\|2625581_2627843_-\|hydratase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
NZ_CP027582.1\|WP_000533654.1\|2622859_2623930_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	3.52815e-61
NZ_CP027582.1\|WP_001091569.1\|2624064_2625348_+\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP027582.1\|WP_000213425.1\|2632914_2633733_+\|pyridoxal-phosphatase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
NZ_CP027582.1\|WP_012817743.1\|2621364_2621667_+\|restriction-alleviation-protein,-Lar-family	gnl\|CDD\|274704	TIGR03655, hypothetical_protein_VT2-Sap32, restriction alleviation protein, Lar family. Restriction alleviation proteins provide a countermeasure to host cell restriction enzyme defense against foreign DNA such as phage or plasmids. This family consists of homologs to the phage antirestriction protein Lar, and most members belong to phage genomes or prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions, DNA metabolism, Restriction/modification].	1.41577e-18
NZ_CP027582.1\|WP_000723652.1\|2629534_2630587_-\|4-oxalomesaconate-tautomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
NZ_CP027582.1\|WP_032278566.1\|2621659_2621944_+\|ASCH-domain-containing-protein	gnl\|CDD\|214979	smart01022, ASCH, The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain. It is thought to function as an RNA-binding domain during coactivation, RNA-processing and possibly during prokaryotic translation regulation.	0.0029297
NZ_CP027582.1\|WP_032277527.1\|2631764_2632760_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
NZ_CP027582.1\|WP_000679972.1\|2630770_2631724_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
NZ_CP027582.1\|WP_001303849.1\|2622663_2622882_+\|excisionase	gnl\|CDD\|116439	pfam07825, Exc, Excisionase-like protein. The phage-encoded excisionase protein (Xis) is involved in excisive recombination by regulating the assembly of the excisive intasome and by inhibiting viral integration. It adopts an unusual 'winged'-helix structure in which two alpha helices are packed against two extended strands. Also present in the structure is a two-stranded anti-parallel beta-sheet, whose strands are connected by a four-residue 'wing'. During interaction with DNA, helix alpha2 is thought to insert into the major groove, while the wing contacts the adjacent minor groove or phosphodiester backbone. The C-terminal region of Xis is involved in interaction with phage-encoded integrase (Int), and a putative C-terminal alpha helix may fold upon interaction with Int and/or DNA.	8.49552e-35
NZ_CP027582.1\|WP_000034231.1\|2620191_2620749_+\|ead/Ea22-like-family-protein	gnl\|CDD\|379401	pfam13935, Ead_Ea22, Ead/Ea22-like protein. This family contains phage proteins and bacterial proteins that are likely to represent integrated phage proteins. This family includes the Lambda phage Ea22 early protein as well as the Bacteriophage P22 Ead protein.	6.64759e-22

>NZ_CP027582.1|WP_001091569.1|2624064_2625348_+|putative-acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>NZ_CP027582.1|WP_000533654.1|2622859_2623930_+|tyrosine-type-recombinase/integrase
MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFSGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITTKEIAAMLSGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNPVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTTLHVDALGISMKETLDKCKEILGGETIIASTHREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
>NZ_CP027582.1|WP_001303849.1|2622663_2622882_+|excisionase
MYLTLQEWNARQRRPRSLETVRRWVRECRIFPPPVKDGREYLFHESAVKVDLNRPVTGSLLKRIRNGKKAKS
>NZ_CP027582.1|WP_001281774.1|2622212_2622557_+|hypothetical-protein
MSDLSMKVLKWQSTGDVGISSATLASIACGLKKNIYGHHFGAPHDAADFRRCVALVEKIPEIRDSFDKVAKRVPAFKGILNEWDSLVALLKSEMKIHGNKAPETYRRISELRKD
>NZ_CP027582.1|WP_000545733.1|2622016_2622184_+|hypothetical-protein
MHFRVTGEWNGEPFNRVIEAENINDCYDHWMIWAQIAHADVTNIRIEELKEHQAA
>NZ_CP027582.1|WP_032278566.1|2621659_2621944_+|ASCH-domain-containing-protein
MANLQLAVKGEYFDAMIRGEKTEEYRLCNDYWNKRIMFREYDRLIITKGYPKRDDSSRRIDVPYDGDEIKTITHPHFGDKPVKVFAIKVNIGNE
>NZ_CP027582.1|WP_012817743.1|2621364_2621667_+|restriction-alleviation-protein,-Lar-family
MNLYRCPFCGSTVLNIGYSFSIRGKMRYVSCKCGAQGPEKRTRSEAISSWNSRMKVWVYDPETILNVEERRRTEVYIHNLNEDGFAPVLVKATPQEVNRG
>NZ_CP027582.1|WP_000104414.1|2620750_2621368_+|hypothetical-protein
MSTITKERIELFIKSPLDNGLTSGEQMELARIALASLEAKPIGAFHIAEQQVDGTSDYLKDGEWPIDNGIIEVYAAPPVPVVPAALPENDDEDGHDIDYLDPSEVYALGRTAGWNACRAAMLQGKSEQPQNAQQNIPENIPGGNSPVTPDGWVMVPKELTPEMMRAVQIRSELGGYATSNLSGAYNMFSEFWNVAVSAAPKVDDL
>NZ_CP027582.1|WP_000034231.1|2620191_2620749_+|ead/Ea22-like-family-protein
MSKIDYQALREAAERAIPAMERLLMLPVDDDLLTEQELKDYGVDIDALNAFKFLTGPETVLALLDERERNQQYIKRRDQKNEDIALTVGKLRVELEAVQKTSAARIEAIDRTHKMFQREKDRADAAEKCIAELSASHSKLRDTMAGIHNTIRMDGGYTPLAAILNAAKRAYEESASAAGIRIKGE
>NZ_CP027582.1|WP_000812206.1|2619637_2620195_+|hypothetical-protein
MKQMTLIEMDGFLKGKCIPSDLKVDETNDEYLVRKFGELESKLETALRECRSAGITIDNLEAKCAKMAAENSSLKQSEKEFNDFCREEFSEWEDDITETPATDAFLAEVKTEARKEGAYFVANRMLAAWEAGFIDDTAKNAADIARMILTSTEFMANAPEGDFDRSFSDGVLEDIAEQLRKGVIQ
>NZ_CP027582.1|WP_000593936.1|2625581_2627843_-|hydratase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>NZ_CP027582.1|WP_001036475.1|2628025_2629459_-|anion-permease
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>NZ_CP027582.1|WP_000723652.1|2629534_2630587_-|4-oxalomesaconate-tautomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>NZ_CP027582.1|WP_000679972.1|2630770_2631724_+|LysR-family-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>NZ_CP027582.1|WP_032277527.1|2631764_2632760_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYSIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENLSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>NZ_CP027582.1|WP_000213425.1|2632914_2633733_+|pyridoxal-phosphatase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>NZ_CP027582.1|WP_000891685.1|2633733_2634792_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMAKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELVIKPGLWLYAQIKSVSITA
>NZ_CP027582.1|WP_000604034.1|2634794_2635484_-|molybdate-ABC-transporter-permease-subunit
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>NZ_CP027582.1|WP_000113001.1|2635483_2636257_-|molybdate-ABC-transporter-substrate-binding-protein
MARKWLNLFAGAALSFAVAGNTLADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTASRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEEHNNATVKAFYDYLKGPQAAEIFKRYGFTTK
>NZ_CP027582.1|WP_000891515.1|2636422_2636572_-|multidrug-efflux-pump-accessory-protein-AcrZ
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: NZ_CP027582_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_5

3467360-3467492

Orphan

Consensus_repeat	Method
ATCACCAATATTGAAAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP027582_5

>merge|NZ_CP027582|5|3467360-3467492|PILER-CR
ATCACCAATATTGAAAATGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTCCTCACCAATATTGAAAACATCGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGGATCACCAATATTGAAAG

>NZ_CP027582|5|2|3467360-3467492|PILER-CR
ATCACCAATATTGAAAA	TGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTC
CTCACCAATATTGAAAA	CATCGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGG
ATCACCAATATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_001183198.1\|3462531_3463863_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP027582.1\|WP_000624375.1\|3459367_3459847_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP027582.1\|WP_001427072.1\|3475581_3476172_+\|carnitine-operon-protein-CaiE	unknown	unknown	gnl\|CDD\|184189
NZ_CP027582.1\|WP_000351348.1\|3473128_3474682_+\|crotonobetaine/carnitine-CoA-ligase	unknown	unknown	gnl\|CDD\|181195
NZ_CP027582.1\|WP_000692206.1\|3466498_3467269_-\|electron-transfer-flavoprotein-FixA	unknown	unknown	gnl\|CDD\|179569
NZ_CP027582.1\|WP_000600725.1\|3461893_3462424_-\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	unknown	unknown	gnl\|CDD\|234852
NZ_CP027582.1\|WP_000203741.1\|3463921_3464209_-\|ferredoxin-like-protein-FixX	unknown	unknown	gnl\|CDD\|185346
NZ_CP027582.1\|WP_001091528.1\|3465542_3466484_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|235120
NZ_CP027582.1\|WP_001287715.1\|3464205_3465492_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182273
NZ_CP027582.1\|WP_000347117.1\|3469287_3470430_+\|crotonobetainyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|179566
NZ_CP027582.1\|WP_000004397.1\|3474790_3475576_+\|crotonobetainyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|179599
NZ_CP027582.1\|WP_000399648.1\|3470666_3471647_+\|IS110-like-element-IS621-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP027582.1\|WP_000597260.1\|3480152_3481301_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP027582.1\|WP_000377129.1\|3460038_3461901_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	unknown	unknown	gnl\|CDD\|235131
NZ_CP027582.1\|WP_000998542.1\|3459167_3459347_-\|antitoxin	unknown	unknown	gnl\|CDD\|377822
NZ_CP027582.1\|WP_000333120.1\|3476257_3476653_-\|carnitine-metabolism-transcriptional-regulator-CaiF	unknown	unknown	gnl\|CDD\|183154
NZ_CP027582.1\|WP_001248979.1\|3458601_3459069_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_001126376.1\|3476913_3480135_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_CP027582.1\|WP_000787103.1\|3467742_3469257_+\|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter	unknown	unknown	gnl\|CDD\|179568
NZ_CP027582.1\|WP_000349932.1\|3471837_3473055_+\|L-carnitine-CoA-transferase	unknown	unknown	gnl\|CDD\|179589

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_001183198.1\|3462531_3463863_-\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.4298e-59
NZ_CP027582.1\|WP_000624375.1\|3459367_3459847_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.07206e-127
NZ_CP027582.1\|WP_001427072.1\|3475581_3476172_+\|carnitine-operon-protein-CaiE	gnl\|CDD\|184189	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional.	6.10339e-142
NZ_CP027582.1\|WP_000692206.1\|3466498_3467269_-\|electron-transfer-flavoprotein-FixA	gnl\|CDD\|179569	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed.	2.43681e-170
NZ_CP027582.1\|WP_000600725.1\|3461893_3462424_-\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	gnl\|CDD\|234852	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF.	2.99389e-133
NZ_CP027582.1\|WP_000203741.1\|3463921_3464209_-\|ferredoxin-like-protein-FixX	gnl\|CDD\|185346	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional.	1.84173e-69
NZ_CP027582.1\|WP_001091528.1\|3465542_3466484_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|235120	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein.	0
NZ_CP027582.1\|WP_001287715.1\|3464205_3465492_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182273	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional.	0
NZ_CP027582.1\|WP_000347117.1\|3469287_3470430_+\|crotonobetainyl-CoA-dehydrogenase	gnl\|CDD\|179566	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated.	0
NZ_CP027582.1\|WP_000004397.1\|3474790_3475576_+\|crotonobetainyl-CoA-hydratase	gnl\|CDD\|179599	PRK03580, PRK03580, crotonobetainyl-CoA hydratase.	4.82171e-178
NZ_CP027582.1\|WP_000399648.1\|3470666_3471647_+\|IS110-like-element-IS621-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	1.78707e-27
NZ_CP027582.1\|WP_000597260.1\|3480152_3481301_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP027582.1\|WP_000377129.1\|3460038_3461901_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
NZ_CP027582.1\|WP_000998542.1\|3459167_3459347_-\|antitoxin	gnl\|CDD\|377822	pfam07362, CcdA, Post-segregation antitoxin CcdA. This family consists of several Enterobacterial post-segregation antitoxin CcdA proteins. The F plasmid-carried bacterial toxin, the CcdB protein, is known to act on DNA gyrase in two different ways. CcdB poisons the gyrase-DNA complex, blocking the passage of polymerases and leading to double-strand breakage of the DNA. Alternatively, in cells that overexpress CcdB, the A subunit of DNA gyrase (GyrA) has been found as an inactive complex with CcdB. Both poisoning and inactivation can be prevented and reversed in the presence of the F plasmid-encoded antidote, the CcdA protein.	2.2737e-08
NZ_CP027582.1\|WP_000333120.1\|3476257_3476653_-\|carnitine-metabolism-transcriptional-regulator-CaiF	gnl\|CDD\|183154	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF.	2.96175e-74
NZ_CP027582.1\|WP_000351348.1\|3473128_3474682_+\|crotonobetaine/carnitine-CoA-ligase	gnl\|CDD\|181195	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated.	0
NZ_CP027582.1\|WP_001126376.1\|3476913_3480135_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP027582.1\|WP_000787103.1\|3467742_3469257_+\|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter	gnl\|CDD\|179568	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter.	0
NZ_CP027582.1\|WP_000349932.1\|3471837_3473055_+\|L-carnitine-CoA-transferase	gnl\|CDD\|179589	PRK03525, PRK03525, L-carnitine CoA-transferase.	0

>NZ_CP027582.1|WP_000692206.1|3466498_3467269_-|electron-transfer-flavoprotein-FixA
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVDAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
>NZ_CP027582.1|WP_001091528.1|3465542_3466484_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGVQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
>NZ_CP027582.1|WP_001287715.1|3464205_3465492_-|FAD-dependent-oxidoreductase
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILADGVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTDGLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYSAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSAMKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFTIDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL
>NZ_CP027582.1|WP_000203741.1|3463921_3464209_-|ferredoxin-like-protein-FixX
MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACPAGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG
>NZ_CP027582.1|WP_001183198.1|3462531_3463863_-|MFS-transporter
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>NZ_CP027582.1|WP_000600725.1|3461893_3462424_-|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF
MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
>NZ_CP027582.1|WP_000377129.1|3460038_3461901_-|glutathione-regulated-potassium-efflux-system-protein-KefC
MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
>NZ_CP027582.1|WP_000624375.1|3459367_3459847_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
>NZ_CP027582.1|WP_000998542.1|3459167_3459347_-|antitoxin
MNDKTFDFTSERDFVSRAHCVGLNLQATLQWNEVNEDAISALNEFAEETGCFSDEYRKF
>NZ_CP027582.1|WP_001248979.1|3458601_3459069_+|hypothetical-protein
MRQINTGLNTREIILEMIDEADAPPFAEQRTWHRRRIAFLCDCISVAVDYGFFCSVSQQSIMNITKMAEDVWITESKTTQLIDIWQQLKQLYPPETIPYAQKLPTKELLELLLSSPDDLRIIEIPDIIGDVFDDQTWIRLFKKHFADVIQLRCDV
>NZ_CP027582.1|WP_000787103.1|3467742_3469257_+|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter
MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
>NZ_CP027582.1|WP_000347117.1|3469287_3470430_+|crotonobetainyl-CoA-dehydrogenase
MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
>NZ_CP027582.1|WP_000399648.1|3470666_3471647_+|IS110-like-element-IS621-family-transposase
MEHELHYIGIDTAKEKLDVDVLRPDGRHRTKKFANTTKGHDELVSWLKGHKIDHAHICIEATGTYMEPVAECLYDAGYIVSVINPALGKAFAQSEGLRNKTDTVDARMLAEFCRQKRPAAWEAPHPLERALRALVVRHQALTDMHTQELNRTETAREVQRPSIDAHLLWLEAELKRLEKQIKDLTDDDPDMKHRRKLLESIPGIGEKTSAVLLAYIGLKDRFAHARQFAAFAGLTPRRYESGSSVRGASRMSKAGHVSLRRALYMPAMVATSKTEWGRAFRDRLAANGKKGKVILGAMMRKLAQVAYGVLKSGVPFDASRHNPVAA
>NZ_CP027582.1|WP_000349932.1|3471837_3473055_+|L-carnitine-CoA-transferase
MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
>NZ_CP027582.1|WP_000351348.1|3473128_3474682_+|crotonobetaine/carnitine-CoA-ligase
MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLLTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
>NZ_CP027582.1|WP_000004397.1|3474790_3475576_+|crotonobetainyl-CoA-hydratase
MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIFRTTSEMPVEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
>NZ_CP027582.1|WP_001427072.1|3475581_3476172_+|carnitine-operon-protein-CaiE
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGSGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>NZ_CP027582.1|WP_000333120.1|3476257_3476653_-|carnitine-metabolism-transcriptional-regulator-CaiF
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVAEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
>NZ_CP027582.1|WP_001126376.1|3476913_3480135_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
>NZ_CP027582.1|WP_000597260.1|3480152_3481301_-|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK

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Crispr_ID: NZ_CP027582_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_6

5052602-5052719

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP027582_6

>merge|NZ_CP027582|6|5052602-5052719|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>NZ_CP027582|6|4|5052602-5052719|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_001297162.1\|5044261_5045470_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP027582.1\|WP_001041010.1\|5053785_5054682_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
NZ_CP027582.1\|WP_000460519.1\|5051270_5052581_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP027582.1\|WP_000861738.1\|5045503_5047798_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NZ_CP027582.1\|WP_000107720.1\|5042904_5044236_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP027582.1\|WP_000104212.1\|5040856_5041795_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP027582.1\|WP_000785722.1\|5057911_5058316_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP027582.1\|WP_000145820.1\|5040323_5040668_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP027582.1\|WP_000633561.1\|5052979_5053681_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP027582.1\|WP_000384145.1\|5055330_5055696_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP027582.1\|WP_000719990.1\|5047811_5048201_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP027582.1\|WP_000531201.1\|5055988_5056975_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223512
NZ_CP027582.1\|WP_001295544.1\|5052792_5052957_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_000401598.1\|5049911_5051243_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP027582.1\|WP_000096086.1\|5057622_5057922_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP027582.1\|WP_001297155.1\|5057044_5057527_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP027582.1\|WP_001198780.1\|5054732_5055089_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP027582.1\|WP_000622115.1\|5048272_5049637_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP027582.1\|WP_000031415.1\|5058318_5058624_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP027582.1\|WP_032276679.1\|5041893_5042883_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_001297162.1\|5044261_5045470_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP027582.1\|WP_001041010.1\|5053785_5054682_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
NZ_CP027582.1\|WP_000460519.1\|5051270_5052581_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0
NZ_CP027582.1\|WP_000861738.1\|5045503_5047798_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP027582.1\|WP_000107720.1\|5042904_5044236_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP027582.1\|WP_000104212.1\|5040856_5041795_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP027582.1\|WP_000785722.1\|5057911_5058316_-\|hypothetical-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP027582.1\|WP_000145820.1\|5040323_5040668_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	3.36123e-66
NZ_CP027582.1\|WP_001198780.1\|5054732_5055089_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35
NZ_CP027582.1\|WP_000384145.1\|5055330_5055696_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
NZ_CP027582.1\|WP_000719990.1\|5047811_5048201_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP027582.1\|WP_000531201.1\|5055988_5056975_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP027582.1\|WP_000633561.1\|5052979_5053681_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	3.10591e-66
NZ_CP027582.1\|WP_000401598.1\|5049911_5051243_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53913e-167
NZ_CP027582.1\|WP_000096086.1\|5057622_5057922_-\|hypothetical-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP027582.1\|WP_001297155.1\|5057044_5057527_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.8408e-29
NZ_CP027582.1\|WP_000622115.1\|5048272_5049637_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP027582.1\|WP_000031415.1\|5058318_5058624_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP027582.1\|WP_032276679.1\|5041893_5042883_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0

>NZ_CP027582.1|WP_000460519.1|5051270_5052581_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP027582.1|WP_000401598.1|5049911_5051243_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP027582.1|WP_000622115.1|5048272_5049637_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP027582.1|WP_000719990.1|5047811_5048201_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP027582.1|WP_000861738.1|5045503_5047798_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVTTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP027582.1|WP_001297162.1|5044261_5045470_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP027582.1|WP_000107720.1|5042904_5044236_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP027582.1|WP_032276679.1|5041893_5042883_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSCVSQITGFVDA
>NZ_CP027582.1|WP_000104212.1|5040856_5041795_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAVVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP027582.1|WP_000145820.1|5040323_5040668_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNIKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP027582.1|WP_001295544.1|5052792_5052957_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP027582.1|WP_000633561.1|5052979_5053681_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPDAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>NZ_CP027582.1|WP_001041010.1|5053785_5054682_+|LysR-family-transcriptional-regulator
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>NZ_CP027582.1|WP_001198780.1|5054732_5055089_-|DUF805-domain-containing-protein
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>NZ_CP027582.1|WP_000384145.1|5055330_5055696_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP027582.1|WP_000531201.1|5055988_5056975_-|glutathione-S-transferase-family-protein
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP027582.1|WP_001297155.1|5057044_5057527_-|DoxX-family-protein
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP027582.1|WP_000096086.1|5057622_5057922_-|hypothetical-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP027582.1|WP_000785722.1|5057911_5058316_-|hypothetical-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP027582.1|WP_000031415.1|5058318_5058624_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: NZ_CP027582_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_7

5449636-5450213

Unclear

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GNGTTCCCCGCGCCAGCGGGGATAAACCG	CRT
TCCCCGCGCCAGCGGGGATAAACC	PILER-CR

9 spacers

The CRISPR arrays of NZ_CP027582_7

>merge|NZ_CP027582|7|5449636-5450213|CRISPRCasFinder,CRT,PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCGATCTCCTCATCCTCCCAGCTACCGACAGTAGTGTGTTCCCCGCGCCAGCGGGGATAAACCGCAAGATCTGCCGCGAGTGGTTTCACCCGGCAGGTGTTCCCCGCGCCAGCGGGGATAAACCGTGGTACGGAACATGCTGTCTATATTTCGACCAGTGTTCCCCGCGCCAGCGGGGATAAACCGCCAGTGGAGCCGCCGCGAATTTACACACGATTGTGTTCCCCGCGCCAGCGGGGATAAACCGTAAGGCCGTCGCCGGATCAGCCTGGCTATGCCGAGCTCCCCGCGCCAGCGGGGATAAACCGTTCTTGCGGGTGTTGCAAATATTCTTCACGTAGAGCTCCCCGCGCCAGCGGGGATAAACCGGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGTTCCCCGCGCCAGCGGGGATAAACCGGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGTTCCCCGCGCCAGCGGGGATAAACCGGACGCCGCCGCCGCGAAGCCGTTTCCGATGTTGAGCTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP027582|7|5|5449636-5450213|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCTCCTCATCCTCCCAGCTACCGACAGTAGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAGATCTGCCGCGAGTGGTTTCACCCGGCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGGTACGGAACATGCTGTCTATATTTCGACCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGTGGAGCCGCCGCGAATTTACACACGATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAGGCCGTCGCCGGATCAGCCTGGCTATGCC
GAGCTCCCCGCGCCAGCGGGGATAAACCG	TTCTTGCGGGTGTTGCAAATATTCTTCACGTA
GAGCTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCCGCCGCCGCGAAGCCGTTTCCGATGTT
GAGCTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP027582|7|1|5449636-5450213|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCTCCTCATCCTCCCAGCTACCGACAGTAGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAAGATCTGCCGCGAGTGGTTTCACCCGGCAG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGGTACGGAACATGCTGTCTATATTTCGACCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGTGGAGCCGCCGCGAATTTACACACGATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAGGCCGTCGCCGGATCAGCCTGGCTATGCC
GAGCTCCCCGCGCCAGCGGGGATAAACCG	TTCTTGCGGGTGTTGCAAATATTCTTCACGTA
GAGCTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GACGCCGCCGCCGCGAAGCCGTTTCCGATGTT
GAGCTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP027582|7|3|5449640-5450212|PILER-CR
TCCCCGCGCCAGCGGGGATAAACC	GATCTCCTCATCCTCCCAGCTACCGACAGTAGTGTGT
TCCCCGCGCCAGCGGGGATAAACC	GCAAGATCTGCCGCGAGTGGTTTCACCCGGCAGGTGT
TCCCCGCGCCAGCGGGGATAAACC	GTGGTACGGAACATGCTGTCTATATTTCGACCAGTGT
TCCCCGCGCCAGCGGGGATAAACC	GCCAGTGGAGCCGCCGCGAATTTACACACGATTGTGT
TCCCCGCGCCAGCGGGGATAAACC	GTAAGGCCGTCGCCGGATCAGCCTGGCTATGCCGAGC
TCCCCGCGCCAGCGGGGATAAACC	GTTCTTGCGGGTGTTGCAAATATTCTTCACGTAGAGC
TCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGT
TCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGT
TCCCCGCGCCAGCGGGGATAAACC	GGACGCCGCCGCCGCGAAGCCGTTTCCGATGTTGAGC
TCCCCGCGCCAGCGGGGATAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_001152074.1\|5454056_5454737_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP027582.1\|WP_001288227.1\|5448345_5448486_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027582.1\|WP_001199970.1\|5448624_5449296_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP027582.1\|WP_001130266.1\|5459453_5460029_-\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP027582.1\|WP_000046800.1\|5439042_5440344_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP027582.1\|WP_000254745.1\|5442951_5443287_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP027582.1\|WP_001341835.1\|5457669_5458449_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP027582.1\|WP_001341834.1\|5458445_5459306_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP027582.1\|WP_000210878.1\|5444376_5446014_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP027582.1\|WP_000021313.1\|5453951_5454047_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|180761
NZ_CP027582.1\|WP_000036723.1\|5446101_5447400_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP027582.1\|WP_001098105.1\|5456354_5457692_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP027582.1\|WP_000226815.1\|5440391_5442626_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP027582.1\|WP_000109366.1\|5460045_5460306_-\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP027582.1\|WP_001268451.1\|5447459_5448332_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP027582.1\|WP_000059323.1\|5454806_5456261_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP027582.1\|WP_001164569.1\|5452356_5453634_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP027582.1\|WP_001071648.1\|5443357_5444149_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP027582.1\|WP_000039758.1\|5450851_5452330_-\|FGGY-family-carbohydrate-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP027582.1\|WP_000581937.1\|5442703_5442952_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_001152074.1\|5454056_5454737_+\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.49633e-125
NZ_CP027582.1\|WP_001199970.1\|5448624_5449296_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.73859e-155
NZ_CP027582.1\|WP_001130266.1\|5459453_5460029_-\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP027582.1\|WP_000046800.1\|5439042_5440344_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP027582.1\|WP_000254745.1\|5442951_5443287_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NZ_CP027582.1\|WP_001341835.1\|5457669_5458449_+\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	3.2021e-62
NZ_CP027582.1\|WP_001341834.1\|5458445_5459306_+\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.55254e-89
NZ_CP027582.1\|WP_000210878.1\|5444376_5446014_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP027582.1\|WP_000021313.1\|5453951_5454047_+\|hypothetical-protein	gnl\|CDD\|180761	PRK06935, PRK06935, 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD.	9.20529e-11
NZ_CP027582.1\|WP_000036723.1\|5446101_5447400_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP027582.1\|WP_001098105.1\|5456354_5457692_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
NZ_CP027582.1\|WP_000226815.1\|5440391_5442626_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP027582.1\|WP_000109366.1\|5460045_5460306_-\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	3.33712e-39
NZ_CP027582.1\|WP_001268451.1\|5447459_5448332_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.01855e-100
NZ_CP027582.1\|WP_000059323.1\|5454806_5456261_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.11123e-80
NZ_CP027582.1\|WP_000581937.1\|5442703_5442952_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP027582.1\|WP_001071648.1\|5443357_5444149_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP027582.1\|WP_000039758.1\|5450851_5452330_-\|FGGY-family-carbohydrate-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.28272e-107
NZ_CP027582.1\|WP_001164569.1\|5452356_5453634_-\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	3.54023e-29

>NZ_CP027582.1|WP_001199970.1|5448624_5449296_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP027582.1|WP_001288227.1|5448345_5448486_-|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNESKITDAAVNLFIQI
>NZ_CP027582.1|WP_001268451.1|5447459_5448332_-|YgcG-family-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKFAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVYISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGKSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>NZ_CP027582.1|WP_000036723.1|5446101_5447400_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP027582.1|WP_000210878.1|5444376_5446014_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP027582.1|WP_001071648.1|5443357_5444149_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP027582.1|WP_000254745.1|5442951_5443287_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP027582.1|WP_000581937.1|5442703_5442952_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP027582.1|WP_000226815.1|5440391_5442626_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP027582.1|WP_000046800.1|5439042_5440344_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVAVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLGSLQVMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLAKQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>NZ_CP027582.1|WP_000039758.1|5450851_5452330_-|FGGY-family-carbohydrate-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGSVVCEGKGLLQPMHTPYADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP027582.1|WP_001164569.1|5452356_5453634_-|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEVRTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP027582.1|WP_000021313.1|5453951_5454047_+|hypothetical-protein
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLG
>NZ_CP027582.1|WP_001152074.1|5454056_5454737_+|SDR-family-oxidoreductase
MALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP027582.1|WP_000059323.1|5454806_5456261_+|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPQEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGTDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP027582.1|WP_001098105.1|5456354_5457692_+|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP027582.1|WP_001341835.1|5457669_5458449_+|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRIEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP027582.1|WP_001341834.1|5458445_5459306_+|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAVKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP027582.1|WP_001130266.1|5459453_5460029_-|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP027582.1|WP_000109366.1|5460045_5460306_-|ferredoxin-family-protein
MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPEGDLRVDYHGCLECGTCCLLCDESTLQQWRYPPSGFGITYRFG

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Crispr_ID: NZ_CP027582_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027582_8

5475914-5476126

TypeI-E

I-E

Consensus_repeat	Method
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP027582_8

>merge|NZ_CP027582|8|5475914-5476126|PILER-CR,CRISPRCasFinder,CRT
TGTGTTCCCCGCGCCAGCGGGGATAAACCGGAAAACCGACAGGTTCACTTACCCGGCCCGACGTGTTCCCCGCGCCAGCGGGGATAAACCGCGGCTATGGAATTTATGGAGAAGTTTGGTTTTGTGTTCCCCGCGTCAGCGGGGATAAACCGGGCGCACTGGATGCGATGATGGATATCACTTAGAATTCCCCGCCCCTGCGGTAGAACTCCC

>NZ_CP027582|8|4|5475914-5476065|PILER-CR
TGTGTTCCCCGCGCCAGCGGGGATAAACCG	GAAAACCGACAGGTTCACTTACCCGGCCCGA
CGTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTATGGAATTTATGGAGAAGTTTGGTTT
TGTGTTCCCCGCGTCAGCGGGGATAAACCG

>NZ_CP027582|8|6|5475915-5476065|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAAAACCGACAGGTTCACTTACCCGGCCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTATGGAATTTATGGAGAAGTTTGGTTTT
GTGTTCCCCGCGTCAGCGGGGATAAACCG

>NZ_CP027582|8|2|5475915-5476126|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAAAACCGACAGGTTCACTTACCCGGCCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTATGGAATTTATGGAGAAGTTTGGTTTT
GTGTTCCCCGCGTCAGCGGGGATAAACCG	GGCGCACTGGATGCGATGATGGATATCACTTA
GAATTCCCCGCCCCTGCGGTAGAACTCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027582.1\|WP_000063176.1\|5475524_5475818_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP027582.1\|WP_001295182.1\|5483490_5484252_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP027582.1\|WP_001090394.1\|5478345_5479773_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP027582.1\|WP_000029342.1\|5471612_5472152_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP027582.1\|WP_000281440.1\|5473957_5474608_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP027582.1\|WP_000372108.1\|5477435_5478344_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP027582.1\|WP_001219242.1\|5481984_5482464_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP027582.1\|WP_000085068.1\|5473229_5473976_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP027582.1\|WP_000490429.1\|5476146_5477184_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP027582.1\|WP_000246138.1\|5481274_5481985_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP027582.1\|WP_001084096.1\|5470053_5471616_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP027582.1\|WP_001173673.1\|5479772_5480378_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP027582.1\|WP_000956458.1\|5466910_5467063_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP027582.1\|WP_001233933.1\|5467256_5469956_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP027582.1\|WP_001246104.1\|5480427_5480751_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP027582.1\|WP_000039843.1\|5465911_5466646_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP027582.1\|WP_000144863.1\|5474604_5475525_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP027582.1\|WP_000206431.1\|5472163_5473219_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP027582.1\|WP_000517476.1\|5480944_5481256_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP027582.1\|WP_032276728.1\|5482460_5483510_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884

Protein	Function_ID	Function_description	E-value
NZ_CP027582.1\|WP_000063176.1\|5475524_5475818_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP027582.1\|WP_001295182.1\|5483490_5484252_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP027582.1\|WP_001090394.1\|5478345_5479773_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP027582.1\|WP_000029342.1\|5471612_5472152_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	7.30002e-26
NZ_CP027582.1\|WP_000281440.1\|5473957_5474608_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.38075e-91
NZ_CP027582.1\|WP_000372108.1\|5477435_5478344_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP027582.1\|WP_001219242.1\|5481984_5482464_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP027582.1\|WP_000085068.1\|5473229_5473976_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	4.95914e-49
NZ_CP027582.1\|WP_000490429.1\|5476146_5477184_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP027582.1\|WP_000246138.1\|5481274_5481985_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP027582.1\|WP_001084096.1\|5470053_5471616_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP027582.1\|WP_001173673.1\|5479772_5480378_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP027582.1\|WP_000956458.1\|5466910_5467063_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP027582.1\|WP_001233933.1\|5467256_5469956_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.31706e-179
NZ_CP027582.1\|WP_001246104.1\|5480427_5480751_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP027582.1\|WP_000039843.1\|5465911_5466646_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP027582.1\|WP_000144863.1\|5474604_5475525_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	4.23259e-157
NZ_CP027582.1\|WP_000206431.1\|5472163_5473219_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	6.10696e-155
NZ_CP027582.1\|WP_000517476.1\|5480944_5481256_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP027582.1\|WP_032276728.1\|5482460_5483510_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0

>NZ_CP027582.1|WP_000063176.1|5475524_5475818_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP027582.1|WP_000144863.1|5474604_5475525_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPQPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRG
>NZ_CP027582.1|WP_000281440.1|5473957_5474608_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELCTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGPAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFVQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP027582.1|WP_000085068.1|5473229_5473976_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP027582.1|WP_000206431.1|5472163_5473219_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWSAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP027582.1|WP_000029342.1|5471612_5472152_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQNQ
>NZ_CP027582.1|WP_001084096.1|5470053_5471616_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKNHGRWDDIWQDGLEAEKLREALLSLEHAFQFGADSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP027582.1|WP_001233933.1|5467256_5469956_+|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>NZ_CP027582.1|WP_000956458.1|5466910_5467063_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP027582.1|WP_000039843.1|5465911_5466646_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP027582.1|WP_000490429.1|5476146_5477184_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP027582.1|WP_000372108.1|5477435_5478344_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP027582.1|WP_001090394.1|5478345_5479773_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGSKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP027582.1|WP_001173673.1|5479772_5480378_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP027582.1|WP_001246104.1|5480427_5480751_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP027582.1|WP_000517476.1|5480944_5481256_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP027582.1|WP_000246138.1|5481274_5481985_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP027582.1|WP_001219242.1|5481984_5482464_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP027582.1|WP_032276728.1|5482460_5483510_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREASFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLNDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP027582.1|WP_001295182.1|5483490_5484252_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP027582_2	2.2\|1856355\|58\|NZ_CP027582\|PILER-CR	1856355-1856412	58	NZ_CP027582.1	508810-508867	1	0.983

1. spacer 2.2|1856355|58|NZ_CP027582|PILER-CR matches to position: 508810-508867, mismatch: 1, identity: 0.983

tgggtatatacaggtgggaaagtgggcaattatgtttcaattttgttaaattccccac	CRISPR spacer
tgggtatatacaggtgggaaagtgggtaattatgtttcaattttgttaaattccccac	Protospacer
**************************.*******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP027582_3	3.1\|2138315\|40\|NZ_CP027582\|CRISPRCasFinder	2138315-2138354	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
NZ_CP027582_5	5.1\|3467377\|42\|NZ_CP027582\|PILER-CR	3467377-3467418	42	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141085-141126	0	1.0
NZ_CP027582_1	1.1\|1189636\|38\|NZ_CP027582\|CRISPRCasFinder	1189636-1189673	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
NZ_CP027582_5	5.2\|3467436\|40\|NZ_CP027582\|PILER-CR	3467436-3467475	40	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141028-141067	2	0.95
NZ_CP027582_8	8.5\|5476066\|32\|NZ_CP027582\|CRT	5476066-5476097	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	3	0.906
NZ_CP027582_8	8.2\|5476005\|31\|NZ_CP027582\|PILER-CR	5476005-5476035	31	NZ_CP050442	Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence	41503-41533	6	0.806
NZ_CP027582_8	8.4\|5476005\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5476005-5476036	32	NZ_CP050442	Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence	41503-41534	6	0.812
NZ_CP027582_7	7.9\|5450153\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5450153-5450184	32	KR080197	Mycobacterium phage FlagStaff, complete genome	15476-15507	7	0.781
NZ_CP027582_8	8.5\|5476066\|32\|NZ_CP027582\|CRT	5476066-5476097	32	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	112768-112799	7	0.781
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NC_012852	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132504, complete sequence	256608-256639	8	0.75
NZ_CP027582_7	7.7\|5450031\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5450031-5450062	32	MK814759	Gordonia phage Reyja, complete genome	4467-4498	8	0.75
NZ_CP027582_7	7.8\|5450092\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5450092-5450123	32	MK814759	Gordonia phage Reyja, complete genome	4467-4498	8	0.75
NZ_CP027582_7	7.9\|5450153\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5450153-5450184	32	NZ_CP014600	Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence	15418-15449	8	0.75
NZ_CP027582_8	8.5\|5476066\|32\|NZ_CP027582\|CRT	5476066-5476097	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1428097-1428128	8	0.75
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP050094	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence	196778-196809	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP050101	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b6, complete sequence	151768-151799	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP050106	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence	508685-508716	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP025016	Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence	133778-133809	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NC_008379	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence	180274-180305	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP053442	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eD, complete sequence	151061-151092	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP018233	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence	21422-21453	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP025506	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence	499023-499054	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP016293	Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence	106143-106174	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP050111	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence	508869-508900	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP048283	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence	130036-130067	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP030763	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence	172635-172666	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP022668	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence	387130-387161	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP022569	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence	4795-4826	9	0.719
NZ_CP027582_7	7.1\|5449665\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449665-5449696	32	NZ_CP050088	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence	158950-158981	9	0.719
NZ_CP027582_7	7.5\|5449909\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5449909-5449940	32	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	224876-224907	9	0.719
NZ_CP027582_7	7.9\|5450153\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5450153-5450184	32	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	139210-139241	9	0.719
NZ_CP027582_8	8.5\|5476066\|32\|NZ_CP027582\|CRT	5476066-5476097	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	141278-141309	9	0.719
NZ_CP027582_7	7.9\|5450153\|32\|NZ_CP027582\|CRISPRCasFinder,CRT	5450153-5450184	32	NZ_CP012383	Streptomyces ambofaciens ATCC 23877 plasmid pSAM1, complete sequence	14130-14161	10	0.688

1. spacer 3.1|2138315|40|NZ_CP027582|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

2. spacer 5.1|3467377|42|NZ_CP027582|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 0, identity: 1.0

tgtcacacgcagataaatccaactttcaatattgttaagttc	CRISPR spacer
tgtcacacgcagataaatccaactttcaatattgttaagttc	Protospacer
******************************************

3. spacer 1.1|1189636|38|NZ_CP027582|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

4. spacer 5.2|3467436|40|NZ_CP027582|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 2, identity: 0.95

catcgcgtagcaaaaagaaattttcaatattgctttatgg	CRISPR spacer
catggcgtagaaaaaagaaattttcaatattgctttatgg	Protospacer
*** ****** *****************************

5. spacer 8.5|5476066|32|NZ_CP027582|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 3, identity: 0.906

ggcgcactggatgcgatgatggatatcactta	CRISPR spacer
gacgcactggatgcgatgatggacatcacttg	Protospacer
*.*********************.*******.

6. spacer 8.2|5476005|31|NZ_CP027582|PILER-CR matches to NZ_CP050442 (Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.806

cggctatggaatttatggagaagtttggttt	CRISPR spacer
ctcctatggaatttatgcagaagtttagtaa	Protospacer
*  ************** ********.**

7. spacer 8.4|5476005|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP050442 (Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

cggctatggaatttatggagaagtttggtttt	CRISPR spacer
ctcctatggaatttatgcagaagtttagtaat	Protospacer
*  ************** ********.**  *

8. spacer 7.9|5450153|32|NZ_CP027582|CRISPRCasFinder,CRT matches to KR080197 (Mycobacterium phage FlagStaff, complete genome) position: , mismatch: 7, identity: 0.781

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
gacgccggcgccgcgatgccgttcgccgggtt	Protospacer
******* ******** ******. * . ***

9. spacer 8.5|5476066|32|NZ_CP027582|CRT matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 7, identity: 0.781

ggcgcactggatgcgatgatggat-atcactta	CRISPR spacer
ggcgcactggctgcgatgaaggacgatcaacc-	Protospacer
********** ******** ***. **** ..

10. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NC_012852 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132504, complete sequence) position: , mismatch: 8, identity: 0.75

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcacc	Protospacer
**...*********** *** *******.* .

11. spacer 7.7|5450031|32|NZ_CP027582|CRISPRCasFinder,CRT matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 8, identity: 0.75

gagcctgacgagactactgaggccgttctgtc-	CRISPR spacer
aagcctgacgaggctactggggcca-gcggtgg	Protospacer
.***********.******.****.  * **

12. spacer 7.8|5450092|32|NZ_CP027582|CRISPRCasFinder,CRT matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 8, identity: 0.75

gagcctgacgagactactgaggccgttctgtc-	CRISPR spacer
aagcctgacgaggctactggggcca-gcggtgg	Protospacer
.***********.******.****.  * **

13. spacer 7.9|5450153|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP014600 (Yangia sp. CCB-MM3 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.75

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
gtcgccgccgccgcgcagccctttccacagcc	Protospacer
* ************* **** *****.  *..

14. spacer 8.5|5476066|32|NZ_CP027582|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

ggcgcactggatgcgatgatggata---tcactta	CRISPR spacer
ggcgcactggaagcggtgatggaggggcgcac---	Protospacer
*********** ***.******* .    ***

15. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP050094 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

16. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP050101 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b6, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

17. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP050106 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

18. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP025016 (Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

19. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NC_008379 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

20. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP053442 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eD, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

21. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP018233 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

22. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP025506 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

23. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP016293 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

24. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP050111 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

25. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP048283 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

26. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP030763 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

27. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP022668 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

28. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP022569 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

29. spacer 7.1|5449665|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP050088 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence) position: , mismatch: 9, identity: 0.719

atctcctcatcctcccagctaccgacagtagt	CRISPR spacer
attctctcatcctccccgctcccgacagcgcc	Protospacer
**...*********** *** *******.. .

30. spacer 7.5|5449909|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

taaggccgtcgccggatcagcctggctatgcc	CRISPR spacer
cggggccgtcgccggatcagccggtctgctgc	Protospacer
...******************* * **..  *

31. spacer 7.9|5450153|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 9, identity: 0.719

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
gaagccgccgccgcgaacccgtttttcccggg	Protospacer
** ************** ******..  .*

32. spacer 8.5|5476066|32|NZ_CP027582|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgcactggatgcgatgatggatatcactta	CRISPR spacer
ggcgcactggaaccgatgatggatgcgatgag	Protospacer
***********  ***********.. *.  .

33. spacer 7.9|5450153|32|NZ_CP027582|CRISPRCasFinder,CRT matches to NZ_CP012383 (Streptomyces ambofaciens ATCC 23877 plasmid pSAM1, complete sequence) position: , mismatch: 10, identity: 0.688

gacgccgccgccgcgaagccgtttccgatgtt	CRISPR spacer
ttgcccgccgcggcgaagccgcttccgtcctc	Protospacer
    ******* *********.***** . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

74243 : 110634

Escherichia_phage(50.0%)

tail,integrase,terminase

attL 77342:77358|attR 117896:117912

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001299507.1\|74243_75710_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.3e-88	39.1
WP_000138282.1\|75778_77356_+	glutamine-hydrolyzing GMP synthase	NA	NA	NA	NA
77342:77358	attL	NA	NA	NA	NA
WP_032277130.1\|77548_78805_+\|integrase	site-specific integrase	A0A0F6TJM5	Escherichia_coli_O157_typing_phage	8.3e-236	98.8
WP_032277128.1\|78807_79467_-	serine/threonine protein phosphatase	K7P6H8	Enterobacteria_phage	7.0e-101	77.2
WP_032277127.1\|79463_80114_-	adenine methylase	A0A2R9YJG0	Escherichia_phage	5.6e-127	99.1
WP_001335975.1\|80106_80358_-	PerC family transcriptional regulator	G9L6A0	Escherichia_phage	3.1e-41	100.0
WP_000675390.1\|80515_80764_-	AlpA family phage regulatory protein	A0A0F6TJ45	Escherichia_coli_O157_typing_phage	3.6e-42	100.0
WP_053878813.1\|80813_81755_-	recombinase RecT	A0A0F6TJP0	Escherichia_coli_O157_typing_phage	2.5e-176	99.0
WP_032277125.1\|81751_82573_-	exodeoxyribonuclease VIII	A0A2R9YJH7	Escherichia_phage	2.0e-158	96.3
WP_001102253.1\|82569_82869_-	hypothetical protein	A0A0F6R7M4	Escherichia_coli_O157_typing_phage	2.5e-45	97.0
WP_000836290.1\|83177_83762_-	helix-turn-helix transcriptional regulator	A0A0F6R8L7	Escherichia_coli_O157_typing_phage	7.0e-105	100.0
WP_001282459.1\|83916_84147_+	hypothetical protein	G9L6A7	Escherichia_phage	2.6e-39	100.0
WP_000402895.1\|84297_84498_+	hypothetical protein	A0A0F6TJB7	Escherichia_coli_O157_typing_phage	2.1e-32	100.0
WP_032277123.1\|84513_85329_+	primosomal protein	Q286X4	Escherichia_phage	9.2e-119	95.3
WP_032277137.1\|85325_86111_+	replication protein	A0A0F6TJ71	Escherichia_coli_O157_typing_phage	7.9e-152	99.2
WP_001231254.1\|86228_86573_+	DUF1064 domain-containing protein	A0A0F6R8N5	Escherichia_coli_O157_typing_phage	1.4e-60	97.4
WP_096858528.1\|86634_87267_+	hypothetical protein	A0A0F6TJR7	Escherichia_coli_O157_typing_phage	2.2e-64	68.5
WP_106875395.1\|87230_87716_+	ead/Ea22-like family protein	A0A0P0ZFW8	Escherichia_phage	3.8e-56	75.8
WP_000403783.1\|87693_88050_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	4.6e-59	100.0
WP_000935422.1\|88100_88313_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	6.6e-37	100.0
WP_001224662.1\|88346_88529_+	hypothetical protein	A0A2R2Z308	Escherichia_phage	1.4e-27	100.0
WP_001289353.1\|88694_89330_+	ead/Ea22-like family protein	A0A2R2Z315	Escherichia_phage	1.3e-115	100.0
WP_000209152.1\|89417_89636_+	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	6.6e-32	100.0
WP_001229296.1\|89637_90003_+	HNH endonuclease	A0A2R2Z2X9	Escherichia_phage	5.1e-69	100.0
WP_106875396.1\|89999_90653_+	DUF551 domain-containing protein	A0A0P0ZD75	Stx2-converting_phage	2.9e-30	87.0
WP_001130062.1\|90767_91106_+	hypothetical protein	A0A0F6TJR3	Escherichia_coli_O157_typing_phage	1.4e-49	86.6
WP_001124396.1\|91123_91336_+	hypothetical protein	Q7Y4V0	Enterobacteria_phage	2.1e-14	52.2
WP_001090120.1\|91332_92007_+\|terminase	terminase small subunit	Q287B7	Escherichia_phage	9.0e-120	100.0
WP_106875397.1\|92003_93479_+\|terminase	terminase	A0A0F6TK57	Escherichia_coli_O157_typing_phage	2.2e-296	99.2
WP_001280570.1\|93569_93941_-	hypothetical protein	A0A0F6TJP2	Escherichia_coli_O157_typing_phage	3.2e-63	98.4
WP_000335899.1\|94648_94855_+	hypothetical protein	G9L6C1	Escherichia_phage	6.0e-11	100.0
WP_000852419.1\|94869_96549_+\|tail	tail protein	G9L6C2	Escherichia_phage	3.6e-303	99.5
WP_000133160.1\|96545_96842_+	hypothetical protein	G9L6C3	Escherichia_phage	1.3e-46	100.0
WP_106875398.1\|96844_97540_+	peptidase	G9L6C4	Escherichia_phage	9.6e-93	98.3
WP_000216335.1\|97554_98541_+	hypothetical protein	G9L6C5	Escherichia_phage	4.3e-187	99.7
WP_000627071.1\|98592_99030_+	hypothetical protein	G9L6C6	Escherichia_phage	6.3e-74	99.3
WP_032277054.1\|99040_99376_+	hypothetical protein	G9L6C7	Escherichia_phage	1.7e-55	99.1
WP_000424495.1\|99426_99750_+	hypothetical protein	A0A0F6R8M8	Escherichia_coli_O157_typing_phage	2.6e-53	98.1
WP_032277056.1\|99749_100355_+	hypothetical protein	A0A0F6TJN5	Escherichia_coli_O157_typing_phage	5.2e-111	99.0
WP_096858558.1\|100354_102826_+	hypothetical protein	G9L6D0	Escherichia_phage	0.0e+00	98.7
WP_000568023.1\|102825_103290_+	hypothetical protein	G9L6D1	Escherichia_phage	8.4e-85	100.0
WP_000336180.1\|103289_103829_+	hypothetical protein	A0A193GYJ4	Enterobacter_phage	1.6e-47	81.8
WP_106875399.1\|103841_106355_+	hypothetical protein	A0A0F6R8M6	Escherichia_coli_O157_typing_phage	0.0e+00	94.1
WP_032277360.1\|106351_108154_+	hypothetical protein	A0A0F6TJQ3	Escherichia_coli_O157_typing_phage	0.0e+00	97.8
WP_032277359.1\|108159_110634_+	phage protein	A0A0F6TK45	Escherichia_coli_O157_typing_phage	0.0e+00	99.2
117896:117912	attR	NA	NA	NA	NA

DBSCAN-SWA_2

115990 : 119562

Salmonella_phage(42.86%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032276644.1\|115990_116395_+	membrane protein	T1SA79	Salmonella_phage	2.9e-65	99.3
WP_016046623.1\|116381_116690_+\|holin	phage holin family protein	T1SA10	Salmonella_phage	2.6e-50	100.0
WP_032276643.1\|116679_117306_+	glycoside hydrolase family 19 protein	Q858F0	Salmonella_phage	1.4e-114	96.6
WP_032276642.1\|117302_117785_+	DUF2514 domain-containing protein	A0A0F6TK39	Escherichia_coli_O157_typing_phage	5.0e-72	91.9
WP_000755172.1\|118004_118544_-	DUF5384 family protein	G9L6F0	Escherichia_phage	9.9e-45	99.4
WP_000669403.1\|118559_119075_-	glycine zipper 2TM domain-containing protein	G9L6F1	Escherichia_phage	6.5e-62	99.4
WP_001344399.1\|119388_119562_-	DUF2633 family protein	G9L6F2	Escherichia_phage	6.8e-24	100.0

DBSCAN-SWA_3

394043 : 507828

117

Enterobacteria_phage(34.94%)

protease,holin,integrase,terminase,lysis,transposase,tail,capsid,head,portal

attL 403034:403052|attR 477279:477297

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000140570.1\|394043_394946_-\|transposase	ISNCY family transposase	Q2A0A7	Sodalis_phage	2.5e-69	54.8
WP_001000358.1\|395139_396330_-	anaerobic glycerol-3-phosphate dehydrogenase subunit C	NA	NA	NA	NA
WP_001209922.1\|396326_397586_-	glycerol-3-phosphate dehydrogenase subunit GlpB	NA	NA	NA	NA
WP_000857257.1\|397575_399204_-	anaerobic glycerol-3-phosphate dehydrogenase subunit A	NA	NA	NA	NA
WP_000948732.1\|399476_400835_+	glycerol-3-phosphate transporter	NA	NA	NA	NA
WP_000779084.1\|400839_401916_+	glycerophosphodiester phosphodiesterase	A0A220BYK6	Staphylococcus_phage	5.1e-08	46.0
WP_000301050.1\|402378_403029_+	lipopolysaccharide kinase InaA	NA	NA	NA	NA
403034:403052	attL	NA	NA	NA	NA
WP_000135040.1\|403082_403337_-	ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE	G9IAA2	Pseudomonas_phage	2.6e-24	73.1
WP_000332036.1\|403336_404467_-	ribonucleotide-diphosphate reductase subunit beta	G9IAA3	Pseudomonas_phage	2.5e-175	78.9
WP_001075177.1\|404555_406841_-	ribonucleoside-diphosphate reductase subunit alpha	A0A2D1GNB1	Pseudoalteromonas_phage	1.1e-283	63.6
WP_032276943.1\|407536_411271_+	AIDA-I family autotransporter adhesin YfaL/EhaC	A0A2L1IV18	Escherichia_phage	2.0e-19	26.5
WP_000990754.1\|411398_412121_-	bifunctional 3-demethylubiquinone 3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase	NA	NA	NA	NA
WP_001281242.1\|412267_414895_+	DNA topoisomerase (ATP-hydrolyzing) subunit A	G3M9Z5	Bacillus_virus	8.1e-92	30.4
WP_001215756.1\|416728_417334_+	DUF1175 domain-containing protein	NA	NA	NA	NA
WP_000533670.1\|417348_418419_-\|integrase	tyrosine-type recombinase/integrase	K7PHK0	Enterobacteria_phage	1.1e-196	98.0
WP_001444001.1\|418396_418615_-	excisionase	K7PKU2	Enterobacteria_phage	2.4e-34	98.6
WP_001281192.1\|418720_419065_-	hypothetical protein	K7PJY7	Enterobacterial_phage	5.3e-60	100.0
WP_000457736.1\|419183_419426_-	DUF4222 domain-containing protein	H6WZF9	Escherichia_phage	3.7e-36	96.2
WP_001345188.1\|419500_419851_-	DUF551 domain-containing protein	A0A077SK54	Escherichia_phage	3.3e-33	80.2
WP_001289868.1\|419847_420453_-	ead/Ea22-like family protein	A0A0K2FJF6	Enterobacteria_phage	1.7e-45	96.9
WP_000763358.1\|420449_420671_-	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	1.6e-33	95.9
WP_001444000.1\|420769_421051_-	cell division protein ZapA	A0A0P0ZBQ0	Stx2-converting_phage	1.9e-47	100.0
WP_000548547.1\|421061_421253_-	DUF1382 family protein	A0A1I9LJM8	Stx_converting_phage	1.9e-27	100.0
WP_001303590.1\|421225_421408_-	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	7.4e-29	100.0
WP_032284635.1\|421407_422085_-	YqaJ viral recombinase family protein	A0A1I9LJM9	Stx_converting_phage	2.3e-131	99.6
WP_000100847.1\|422081_422867_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995439.1\|422872_423169_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000372926.1\|423223_423388_-	host cell division inhibitory peptide Kil	A0A0P0ZC96	Stx2-converting_phage	3.2e-23	98.1
WP_001198860.1\|423356_423521_-\|protease	protease FtsH-inhibitory lysogeny factor CIII	A0A0N6WES3	Escherichia_phage	1.4e-26	100.0
WP_000065385.1\|423593_423962_-	DUF2528 family protein	M1FPD2	Enterobacteria_phage	3.8e-64	97.5
WP_000167595.1\|424111_424582_-	hypothetical protein	A0A1I9LJN4	Stx_converting_phage	3.7e-88	100.0
WP_000930321.1\|424715_425054_-	hypothetical protein	K7PJW2	Enterobacteria_phage	5.8e-59	99.1
WP_000256573.1\|425056_425362_-	hypothetical protein	K7PJM7	Enterobacteria_phage	7.0e-48	99.0
WP_001095982.1\|425676_426327_-	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	4.9e-123	100.0
WP_000276885.1\|426407_426593_+	hypothetical protein	K7PHK4	Enterobacteria_phage	1.2e-26	100.0
WP_000035947.1\|426702_426999_+	hypothetical protein	A0A0N7C1W0	Escherichia_phage	1.3e-46	96.9
WP_000185462.1\|427031_427970_+	replication protein	C1JJ53	Enterobacteria_phage	1.1e-171	99.4
WP_000788878.1\|427966_428668_+	Replication protein 14	K7P6G2	Enterobacteria_phage	1.7e-129	99.6
WP_000145926.1\|428664_428955_+	protein ren	O48423	Enterobacteria_phage	9.6e-47	100.0
WP_000229807.1\|429027_429234_+	hypothetical protein	G8C7M4	Escherichia_phage	1.8e-26	97.1
WP_000810176.1\|429241_429688_+	recombination protein NinB	A0A0N7C2V1	Escherichia_phage	3.4e-75	92.6
WP_000153270.1\|429684_430212_+	phage N-6-adenine-methyltransferase	K7PJZ4	Enterobacterial_phage	9.5e-101	100.0
WP_001254228.1\|430208_430391_+	NinE family protein	A0A1U9AJF6	Stx1_converting_phage	1.1e-29	100.0
WP_001429269.1\|430894_432730_-	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	0.0e+00	99.7
WP_001108084.1\|433235_433802_+	endonuclease	A0A1U9AJK5	Stx1_converting_phage	6.6e-108	99.5
WP_001223927.1\|433776_434379_+	recombination protein NinG	A0A1U9AJF8	Stx1_converting_phage	1.6e-91	94.6
WP_001028854.1\|434375_435041_+	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001235460.1\|435037_435661_+	antitermination protein	K7PM87	Enterobacteria_phage	9.8e-113	98.6
WP_001302581.1\|435913_436657_+	hypothetical protein	NA	NA	NA	NA
WP_000499454.1\|436742_436901_+	DUF3927 family protein	NA	NA	NA	NA
WP_012578864.1\|436981_437380_-	hypothetical protein	H6WZJ8	Escherichia_phage	6.9e-11	83.3
WP_000284524.1\|437522_437738_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000075153.1\|437737_438235_+	lysozyme	A0A1B5FP97	Escherichia_phage	1.6e-89	96.4
WP_001228695.1\|438451_438634_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_000738423.1\|438724_439018_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
WP_001427981.1\|439377_439572_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.4e-27	95.3
WP_000235436.1\|439966_440476_+\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_001444182.1\|440447_442157_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	2.9e-239	67.5
WP_001238637.1\|442169_442376_+\|terminase	terminase	A0A2I6TC92	Escherichia_phage	1.1e-12	59.4
WP_000258991.1\|442359_442566_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	4.2e-12	60.0
WP_000827572.1\|442562_444155_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	8.4e-185	61.3
WP_001254039.1\|444144_445650_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.6e-100	54.0
WP_000256849.1\|445686_446034_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.5e-22	58.1
WP_000522643.1\|446091_446976_+	hypothetical protein	C6ZCY2	Enterobacteria_phage	6.5e-94	54.1
WP_000201528.1\|447027_447402_+	hypothetical protein	NA	NA	NA	NA
WP_001204544.1\|447394_447748_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	2.5e-41	69.2
WP_000975037.1\|447762_448338_+\|tail	tail protein	A0A2R9YJK4	Escherichia_phage	7.5e-51	58.7
WP_000683071.1\|448334_448730_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	4.2e-61	87.0
WP_001143013.1\|448737_449490_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.7e-127	93.6
WP_000479086.1\|449503_449935_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	4.8e-42	68.1
WP_000533403.1\|449961_450375_+\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_000082375.1\|450355_452917_+\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	95.0
WP_000847413.1\|452913_453243_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	1.3e-52	91.7
WP_106875401.1\|453242_453941_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.1e-132	98.7
WP_000194778.1\|453946_454690_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	6.6e-148	97.2
WP_000090884.1\|454626_455259_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	8.5e-96	99.0
WP_032284631.1\|455319_458619_+	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	95.2
WP_000839179.1\|458647_459052_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_000612626.1\|459048_459396_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000099160.1\|459444_460983_+\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_001230644.1\|461045_461261_+	hypothetical protein	Q9LA64	Enterobacterial_phage	2.9e-32	95.8
WP_001228241.1\|461328_461928_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	2.4e-100	91.0
WP_000279018.1\|461992_463306_+\|tail	tail fiber protein	A0A0P0ZCC1	Stx2-converting_phage	2.8e-77	97.3
WP_001023380.1\|463307_463577_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	7.3e-41	94.4
WP_001025665.1\|465143_466466_-	type III secretion system effector NleA	H6WZN2	Escherichia_phage	9.7e-227	85.5
WP_001676637.1\|467267_471662_+	alpha-2-macroglobulin family protein	NA	NA	NA	NA
WP_032276988.1\|471662_473312_+	DUF2300 domain-containing protein	NA	NA	NA	NA
WP_001225855.1\|473316_474093_+	YfaP family protein	NA	NA	NA	NA
WP_032277553.1\|474367_477217_+	two-component system sensor histidine kinase RcsC	A0A1V0SGX0	Hokovirus	9.2e-41	27.0
WP_001061917.1\|477302_477953_-	transcriptional regulator RcsB	NA	NA	NA	NA
477279:477297	attR	NA	NA	NA	NA
WP_001249127.1\|477969_480642_-	phosphotransferase RcsD	NA	NA	NA	NA
WP_032278818.1\|481380_482472_+	porin OmpC	Q1MVN1	Enterobacteria_phage	9.4e-119	60.1
WP_000406116.1\|482583_483639_+	FAD:protein FMN transferase ApbE	NA	NA	NA	NA
WP_000786386.1\|483712_484777_+	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	1.8e-18	50.5
WP_000884922.1\|484776_485427_+	DNA oxidative demethylase AlkB	A0A2K9L3R7	Tupanvirus	1.4e-05	31.7
WP_000422231.1\|485502_487146_+	microcin J25 efflux ABC transporter YojI	W8CYL7	Bacillus_phage	9.5e-14	24.0
WP_000758074.1\|487363_489010_+	malate dehydrogenase (quinone)	NA	NA	NA	NA
WP_000849214.1\|489158_489647_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_001296837.1\|489782_489947_-	hypothetical protein	NA	NA	NA	NA
WP_000686723.1\|490055_490550_+	ferredoxin-type protein NapF	NA	NA	NA	NA
WP_000557378.1\|490539_490803_+	chaperone NapD	NA	NA	NA	NA
WP_032277551.1\|490799_493286_+	periplasmic nitrate reductase subunit alpha	NA	NA	NA	NA
WP_000091291.1\|493292_493988_+	ferredoxin-type protein NapG	NA	NA	NA	NA
WP_000013509.1\|493974_494838_+	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
WP_000835177.1\|494834_495284_+	nitrate reductase cytochrome c-type subunit	NA	NA	NA	NA
WP_000528376.1\|495293_495896_+	cytochrome c-type protein NapC	NA	NA	NA	NA
WP_000888560.1\|495914_496532_+	cytochrome c biogenesis heme-transporting ATPase CcmA	G3M9Y6	Bacillus_virus	1.9e-12	25.5
WP_000971723.1\|496528_497191_+	heme exporter protein CcmB	NA	NA	NA	NA
WP_001295447.1\|497232_497970_+	heme exporter protein CcmC	NA	NA	NA	NA
WP_000186540.1\|497966_498176_+	heme exporter protein CcmD	NA	NA	NA	NA
WP_001026418.1\|498172_498652_+	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_000982426.1\|498648_500592_+	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_000824439.1\|500588_501146_+	thiol:disulfide interchange protein DsbE	NA	NA	NA	NA
WP_001211567.1\|501142_502195_+	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_001113637.1\|502229_502877_-	nitrate/nitrite response regulator protein NarP	NA	NA	NA	NA
WP_001369202.1\|506253_507177_-\|capsid	phage capsid protein	A0A0R6PHC6	Moraxella_phage	1.2e-13	24.9
WP_001229488.1\|507339_507828_-\|terminase	terminase small subunit	A0A0P0ZCQ9	Stx2-converting_phage	3.9e-24	41.7

DBSCAN-SWA_4

585337 : 595265

Enterobacteria_phage(62.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001240401.1\|585337_586069_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|586290_587976_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|587972_588692_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000950404.1\|588738_589209_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	2.0e-81	99.4
WP_000998019.1\|589640_591026_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.4e-259	89.3
WP_000612591.1\|591075_591423_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171523.1\|591419_591800_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_001342301.1\|592131_594132_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.0
WP_001292774.1\|594128_595265_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7

DBSCAN-SWA_5

828817 : 885724

Enterobacteria_phage(80.95%)

holin,integrase,terminase,transposase,tail,plate,head,capsid,portal

attL 848496:848555|attR 885831:885951

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000826451.1\|828817_829981_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	8.9e-200	93.0
WP_000334586.1\|829965_830637_-	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	5.6e-82	60.8
WP_000790504.1\|830745_830979_-	sulfurtransferase-like selenium metabolism protein YedF	NA	NA	NA	NA
WP_000118901.1\|830975_832181_-	selenium metabolism membrane protein YedE/FdhT	NA	NA	NA	NA
WP_001295642.1\|832367_832781_+	lipoprotein	NA	NA	NA	NA
WP_001245684.1\|832814_834302_-	alpha-amylase	NA	NA	NA	NA
WP_001015030.1\|834379_834745_-	flagella biosynthesis regulatory protein FliT	NA	NA	NA	NA
WP_000287768.1\|834744_835155_-	flagellar export chaperone FliS	NA	NA	NA	NA
WP_032276835.1\|835169_836582_-	flagellar filament capping protein FliD	NA	NA	NA	NA
WP_000079829.1\|836836_838411_+	hypothetical protein	NA	NA	NA	NA
WP_032276834.1\|838575_839295_+	RNA polymerase sigma factor FliA	NA	NA	NA	NA
WP_001370462.1\|839340_839892_+	flagella biosynthesis regulatory protein FliZ	NA	NA	NA	NA
WP_001317901.1\|839979_840780_+	cystine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001128238.1\|840884_841871_+	D-cysteine desulfhydrase	NA	NA	NA	NA
WP_001158220.1\|841885_842554_+	cystine ABC transporter permease	NA	NA	NA	NA
WP_001272994.1\|842550_843303_+	L-cystine ABC transporter ATP-binding protein YecC	G3M9Y6	Bacillus_virus	3.8e-26	34.9
WP_001154265.1\|843532_844255_+	transcriptional regulator SdiA	NA	NA	NA	NA
WP_000106474.1\|844322_844547_-	DUF2594 family protein	NA	NA	NA	NA
WP_001342215.1\|844533_844710_-	hypothetical protein	NA	NA	NA	NA
WP_000611328.1\|845005_845662_+	UvrY/SirA/GacA family response regulator transcription factor	NA	NA	NA	NA
WP_001283424.1\|845658_847491_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_001160187.1\|847547_848096_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
848496:848555	attL	NA	NA	NA	NA
WP_001303543.1\|849088_849370_+	hypothetical protein	NA	NA	NA	NA
WP_000078920.1\|849558_849699_-	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	7.0e-19	100.0
WP_000488107.1\|849889_850150_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_001317900.1\|850439_851579_-	SEC-C domain-containing protein	NA	NA	NA	NA
WP_000132847.1\|851978_853079_-	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	2.1e-203	98.6
WP_032250563.1\|853236_854421_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	2.2e-222	98.2
WP_000290450.1\|854420_854933_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	3.2e-93	100.0
WP_000665308.1\|854987_855353_+\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	3.8e-56	97.5
WP_000763327.1\|855388_855517_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	3.0e-16	97.6
WP_000853454.1\|855503_858311_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	96.7
WP_000979948.1\|858323_858812_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	2.6e-84	98.8
WP_000954196.1\|858968_859541_+	serine acetyltransferase	NA	NA	NA	NA
WP_000144010.1\|859584_860163_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.2e-95	88.5
WP_106875403.1\|860162_862295_-\|tail	phage tail protein	U5N099	Enterobacteria_phage	2.7e-130	66.4
WP_000071738.1\|862297_862828_-\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	4.3e-93	98.8
WP_001111967.1\|862820_863717_-\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	1.9e-154	97.7
WP_000213447.1\|863720_864071_-\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	9.2e-60	100.0
WP_001271909.1\|864067_864649_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	1.2e-101	97.4
WP_032276831.1\|864645_865281_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	4.1e-114	99.5
WP_001342220.1\|865273_865741_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	6.7e-82	94.8
WP_000202144.1\|865764_867642_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	1.1e-305	82.2
WP_000780555.1\|867780_868188_-	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	4.2e-64	95.6
WP_000072343.1\|868184_868577_-	M15 family metallopeptidase	A0A0A7NQ86	Enterobacteria_phage	2.9e-70	98.5
WP_001342221.1\|868573_868897_-\|holin	holin	A0A0A7NRY9	Enterobacteria_phage	1.7e-47	93.5
WP_000864911.1\|868899_869100_-\|tail	tail protein	A0A0A7NV57	Enterobacteria_phage	7.9e-32	98.5
WP_000063100.1\|869099_869594_-\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	1.9e-87	97.0
WP_106875404.1\|869695_870496_-\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	1.3e-125	88.7
WP_024219921.1\|870541_871594_-\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	4.9e-189	94.6
WP_001262655.1\|871617_872454_-\|capsid	phage capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	2.7e-150	99.6
WP_000613774.1\|872608_874360_+\|terminase	terminase	A0A0A7NV54	Enterobacteria_phage	0.0e+00	98.1
WP_000087812.1\|874359_875406_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.5e-206	100.0
WP_001289969.1\|875896_876487_-	ead/Ea22-like family protein	Q8HAA6	Salmonella_phage	1.8e-31	50.7
WP_000211289.1\|876550_876862_-	chromosome partitioning protein	A0A0A7NPT5	Enterobacteria_phage	1.2e-47	95.1
WP_000686499.1\|876866_877826_-	recombinase	A0A0A7NPX4	Enterobacteria_phage	2.0e-181	99.7
WP_001272083.1\|877902_880743_-	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	88.6
WP_000564221.1\|880739_881129_-	hypothetical protein	NA	NA	NA	NA
WP_000985152.1\|881452_881656_-	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	9.5e-25	80.6
WP_000021647.1\|881742_881856_-	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	2.4e-09	91.9
WP_000357025.1\|881852_882095_-	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	3.4e-37	97.5
WP_000158976.1\|882106_882385_-	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	6.9e-34	77.2
WP_000742491.1\|882395_882746_-	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	1.2e-48	81.0
WP_000014504.1\|882767_882971_-	DNA-binding protein	P79674	Haemophilus_phage	3.1e-07	45.2
WP_001673482.1\|883042_883180_+	hypothetical protein	NA	NA	NA	NA
WP_000786769.1\|883269_883674_+	transcriptional regulator	Q6QID2	Burkholderia_phage	1.6e-23	53.8
WP_000290352.1\|883689_884340_+	membrane protein	NA	NA	NA	NA
WP_000865208.1\|884369_884717_+	DUF2511 domain-containing protein	NA	NA	NA	NA
WP_001342226.1\|884722_885724_+\|integrase	tyrosine-type recombinase/integrase	Q94N03	Haemophilus_virus	9.3e-105	58.2
885831:885951	attR	NA	NA	NA	NA

DBSCAN-SWA_6

969760 : 1051332

Escherichia_phage(33.87%)

holin,protease,tRNA,integrase,terminase,lysis,tail,capsid,head,portal

attL 962031:962045|attR 982786:982800

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
962031:962045	attL	NA	NA	NA	NA
WP_000916763.1\|969760_969991_-	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.3e-14	61.8
WP_000204699.1\|970129_970504_+	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_000879280.1\|970507_971380_+	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_000976492.1\|971392_971734_+	YebY family protein	NA	NA	NA	NA
WP_001189091.1\|972126_973203_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	5.3e-98	51.7
WP_001443927.1\|973168_973450_-	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.7e-11	41.2
WP_001356607.1\|973556_973745_-	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	1.6e-18	97.9
WP_042853000.1\|973737_973932_-	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	7.6e-32	96.9
WP_000166317.1\|973988_974798_-	recombination protein RecT	A0A1P8DTF2	Proteus_phage	6.8e-106	71.5
WP_000105101.1\|974790_977442_-	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	0.0e+00	77.6
WP_001307773.1\|977540_977816_-	hypothetical protein	A0A0U2QW85	Escherichia_phage	3.0e-42	96.7
WP_001427414.1\|977889_978060_-	hypothetical protein	A0A0U2SHB5	Escherichia_phage	3.3e-23	89.3
WP_000560218.1\|978059_978281_-	killing protein KilR	A0A0U2RTC4	Escherichia_phage	1.8e-37	98.6
WP_001427316.1\|978701_978854_-	DUF1391 family protein	M4QQ57	Salicola_phage	2.3e-07	55.3
WP_001303511.1\|979140_979419_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_001302048.1\|979420_979612_-	hypothetical protein	NA	NA	NA	NA
WP_001169687.1\|979632_980004_-	hypothetical protein	NA	NA	NA	NA
WP_000172738.1\|980102_980405_+	transcriptional regulator	K7PHA1	Enterobacteria_phage	8.6e-06	34.8
WP_000693943.1\|980401_980827_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001444941.1\|980849_981812_+	DNA-binding protein	U5P0A0	Shigella_phage	2.7e-69	51.5
WP_000450872.1\|982585_983347_+	DUF1627 domain-containing protein	A0A088CE47	Shigella_phage	3.9e-79	67.2
982786:982800	attR	NA	NA	NA	NA
WP_000603384.1\|983379_983661_+	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
WP_000699809.1\|983657_983885_+	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
WP_001289673.1\|983877_984189_+	hypothetical protein	A0A0U2QV73	Escherichia_phage	7.2e-56	92.2
WP_000683609.1\|984316_984535_+	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	2.3e-21	72.2
WP_000104474.1\|984536_985094_+	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
WP_000935259.1\|985327_985540_+	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_000756596.1\|985659_986004_+	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_000191872.1\|986125_986398_+	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_032284663.1\|986399_987449_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	3.4e-110	54.6
WP_001217413.1\|987461_987836_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.4e-34	63.6
WP_000762928.1\|987832_988654_+	antitermination protein	K7P7B9	Enterobacteria_phage	4.1e-82	61.2
WP_032284665.1\|989824_991675_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.6
WP_000411802.1\|992122_992329_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000075132.1\|992328_992826_+	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_000092325.1\|992822_993260_+\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	1.7e-71	98.6
WP_000881326.1\|993409_994027_+	hypothetical protein	A0A1R3Y613	Salmonella_virus	6.5e-93	85.9
WP_001307652.1\|994214_994409_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
WP_000453587.1\|994797_995343_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_001027379.1\|995317_997243_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.1
WP_000198153.1\|997239_997446_+\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_024026143.1\|997442_999044_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	2.1e-308	98.9
WP_000123251.1\|999024_1000344_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	7.6e-232	97.9
WP_001365129.1\|1000353_1000686_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.5e-54	98.2
WP_000063258.1\|1000741_1001767_+\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	5.1e-191	98.8
WP_000158897.1\|1001808_1002204_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.4e-56	93.9
WP_000752994.1\|1002215_1002569_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.0e-63	100.0
WP_000975096.1\|1002580_1003159_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000683137.1\|1003155_1003551_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	3.7e-65	92.4
WP_032325228.1\|1003558_1004311_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.3e-130	95.6
WP_000479045.1\|1004324_1004747_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	1.7e-71	98.6
WP_000533440.1\|1004773_1005187_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_106875406.1\|1005167_1007780_+\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	91.0
WP_000847280.1\|1007776_1008106_+\|tail	phage tail protein	S5MW28	Escherichia_phage	1.2e-58	99.1
WP_032284485.1\|1008105_1008804_+\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	4.9e-129	96.1
WP_106875407.1\|1008814_1009558_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.0e-148	97.6
WP_072148784.1\|1009503_1010136_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	2.9e-104	93.3
WP_106875408.1\|1010381_1013774_+	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	84.7
WP_001230428.1\|1013841_1014441_+	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	1.4e-111	99.5
WP_032284483.1\|1014505_1015819_+\|tail	tail fiber protein	Q9EYE8	Enterobacteria_phage	1.3e-77	99.5
WP_001023379.1\|1015820_1016090_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	8.7e-42	95.5
WP_000491545.1\|1016230_1017106_+	hypothetical protein	A0A0P0ZCT1	Stx2-converting_phage	7.2e-162	99.7
WP_001121225.1\|1017330_1017981_-	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_000812724.1\|1018935_1019592_+	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	3.1e-56	50.2
WP_001296140.1\|1019592_1019784_-	YebW family protein	NA	NA	NA	NA
WP_001295499.1\|1019888_1020125_-	DUF1480 family protein	NA	NA	NA	NA
WP_000057024.1\|1020242_1021682_-	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_001299674.1\|1021761_1024395_-	lipid-binding membrane homeostasis protein YebT	NA	NA	NA	NA
WP_001207284.1\|1024363_1025647_-	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_001043882.1\|1025776_1026274_+	GAF domain-containing protein	NA	NA	NA	NA
WP_000431370.1\|1026370_1027069_+	RNA chaperone ProQ	NA	NA	NA	NA
WP_001427396.1\|1027088_1029137_+	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	6.8e-86	33.5
WP_000984517.1\|1029328_1030210_+\|protease	protease HtpX	NA	NA	NA	NA
WP_001127210.1\|1030255_1031629_-	MFS transporter	NA	NA	NA	NA
WP_001262174.1\|1031805_1032597_+	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
WP_001211011.1\|1032739_1032979_-	hypothetical protein	NA	NA	NA	NA
WP_000714550.1\|1033137_1033281_+	PhoP/PhoQ regulator MgrB	NA	NA	NA	NA
WP_001006866.1\|1033355_1033643_+	hypothetical protein	NA	NA	NA	NA
WP_001295496.1\|1034311_1034455_+	YobF family protein	NA	NA	NA	NA
WP_001062678.1\|1034467_1034677_+	transcription antiterminator/RNA stability regulator CspE	A0A1W6JNX5	Morganella_phage	1.6e-22	78.1
WP_000010107.1\|1034842_1035652_+	23S rRNA (guanine(745)-N(1))-methyltransferase	NA	NA	NA	NA
WP_001296134.1\|1035648_1036215_-	manganese efflux pump MntP	NA	NA	NA	NA
WP_000156255.1\|1036643_1037102_-	DUF986 domain-containing protein	NA	NA	NA	NA
WP_000228655.1\|1037156_1038008_-	PTS mannose transporter subunit IID	NA	NA	NA	NA
WP_000406926.1\|1038020_1038821_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_000150551.1\|1038883_1039855_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_000394983.1\|1040317_1041874_+	CNNM family cation transport protein YoaE	A0A0R6PEZ3	Moraxella_phage	1.7e-41	45.4
WP_001295494.1\|1041877_1043476_-	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
WP_000624298.1\|1043606_1044971_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_000456725.1\|1045154_1045733_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_000854972.1\|1045736_1047098_-	aminodeoxychorismate synthase component 1	S4VT78	Pandoravirus	3.4e-41	33.4
WP_000457334.1\|1047171_1047351_+	YoaH family protein	NA	NA	NA	NA
WP_001307845.1\|1047470_1047830_-	DUF1889 family protein	NA	NA	NA	NA
WP_001295493.1\|1048192_1048537_-	RidA family protein	NA	NA	NA	NA
WP_000128847.1\|1048668_1050579_+	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	4.5e-92	31.9
WP_001221003.1\|1050636_1051332_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA

DBSCAN-SWA_7

1263191 : 1329293

Enterobacteria_phage(32.76%)

protease,holin,integrase,terminase,lysis,transposase,tail,capsid,head,portal

attL 1277818:1277832|attR 1286119:1286133

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001260840.1\|1263191_1264013_-\|protease	serine protease	NA	NA	NA	NA
WP_000233090.1\|1264112_1264196_-	hypothetical protein	NA	NA	NA	NA
WP_000743951.1\|1264288_1264624_-	acid shock protein	NA	NA	NA	NA
WP_000091840.1\|1265020_1266274_-	MFS transporter	NA	NA	NA	NA
WP_001019545.1\|1266380_1267274_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000225276.1\|1267408_1268629_+	DNA-binding transcriptional repressor Mlc	NA	NA	NA	NA
WP_000919226.1\|1268753_1269449_+	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_001315626.1\|1269401_1270694_-	voltage-gated ClC-type chloride channel ClcB	NA	NA	NA	NA
WP_000148710.1\|1270852_1271467_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	8.7e-29	36.3
WP_000526492.1\|1271509_1272364_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
WP_000213028.1\|1272365_1272983_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	9.5e-76	59.6
WP_001342196.1\|1272993_1275417_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	2.2e-208	48.6
1277818:1277832	attL	NA	NA	NA	NA
WP_001307224.1\|1278101_1278407_-	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_001321287.1\|1278514_1279225_+	YnfC family lipoprotein	NA	NA	NA	NA
WP_001138576.1\|1279227_1279788_-	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_000705211.1\|1279822_1280164_-	DUF1283 family protein	NA	NA	NA	NA
WP_000598292.1\|1280298_1280625_+	YnfA family protein	A0A218MNG8	uncultured_virus	9.9e-24	55.6
WP_001295394.1\|1280830_1282045_+	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	1.4e-46	29.0
WP_000836079.1\|1282056_1283076_+	Zn-dependent oxidoreductase	E3SJ82	Synechococcus_phage	9.7e-17	25.9
WP_072095801.1\|1283133_1283244_+	transporter	NA	NA	NA	NA
WP_001206148.1\|1283263_1284559_-\|integrase	site-specific integrase	B6DZ48	Enterobacteria_phage	2.5e-155	62.3
WP_001368608.1\|1284578_1284815_-	excisionase family protein	S4TND0	Salmonella_phage	6.1e-15	50.7
WP_000048585.1\|1284899_1287371_-	exonuclease	A0A192Y6E0	Salmonella_phage	1.9e-58	58.0
1286119:1286133	attR	NA	NA	NA	NA
WP_001098307.1\|1287464_1287656_-	DUF1482 family protein	NA	NA	NA	NA
WP_000413705.1\|1287652_1287841_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001133037.1\|1288408_1288618_+	hypothetical protein	NA	NA	NA	NA
WP_000394548.1\|1288618_1289257_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_000379562.1\|1289268_1289421_-	DUF1391 family protein	M4QQ57	Salicola_phage	7.8e-08	55.3
WP_000362153.1\|1289686_1290106_-	hypothetical protein	K7PK07	Enterobacteria_phage	8.8e-25	65.1
WP_000391950.1\|1290206_1290488_+	hypothetical protein	K7PHA1	Enterobacteria_phage	6.5e-24	72.6
WP_000693888.1\|1290471_1290897_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000095674.1\|1290919_1291888_+	DNA-binding protein	U5P0A0	Shigella_phage	1.8e-73	52.7
WP_000790459.1\|1291894_1292635_+	ATP-binding protein	A0A088CBP4	Shigella_phage	6.2e-114	83.1
WP_000450862.1\|1292664_1293435_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	3.7e-85	67.6
WP_001141099.1\|1293450_1293843_+	DUF977 family protein	A0A088CBK9	Shigella_phage	1.5e-39	63.3
WP_024182342.1\|1293839_1294136_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	2.3e-48	95.9
WP_001018050.1\|1294132_1294414_+	DUF4752 family protein	A0A222YWQ2	Escherichia_phage	1.8e-34	80.9
WP_001002668.1\|1294653_1294965_+	hypothetical protein	A0A222YY67	Escherichia_phage	9.0e-51	82.5
WP_000256992.1\|1295092_1295311_+	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	5.2e-29	91.7
WP_032244186.1\|1295312_1295849_+	DUF551 domain-containing protein	K7PH57	Enterobacteria_phage	1.7e-60	55.2
WP_000787530.1\|1295848_1296244_+	hypothetical protein	A0A193GYM6	Enterobacter_phage	8.6e-38	62.0
WP_000128514.1\|1296478_1296691_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	9.6e-28	94.3
WP_001341388.1\|1296858_1297137_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265151.1\|1297138_1298188_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	3.2e-108	54.0
WP_001217425.1\|1298200_1298560_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	4.6e-38	66.7
WP_001064874.1\|1298556_1299225_+	antiterminator	I6PDF8	Cronobacter_phage	8.7e-59	51.1
WP_032284474.1\|1299928_1301779_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.3
WP_000411802.1\|1302226_1302433_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000075132.1\|1302432_1302930_+	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_000092325.1\|1302926_1303364_+\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	1.7e-71	98.6
WP_000881326.1\|1303513_1304131_+	hypothetical protein	A0A1R3Y613	Salmonella_virus	6.5e-93	85.9
WP_001307652.1\|1304318_1304513_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
WP_000453587.1\|1304901_1305447_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_001027379.1\|1305421_1307347_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.1
WP_000198153.1\|1307343_1307550_+\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_024026143.1\|1307546_1309148_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	2.1e-308	98.9
WP_000123251.1\|1309128_1310448_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	7.6e-232	97.9
WP_001365129.1\|1310457_1310790_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.5e-54	98.2
WP_000063258.1\|1310845_1311871_+\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	5.1e-191	98.8
WP_000158897.1\|1311912_1312308_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.4e-56	93.9
WP_000752994.1\|1312319_1312673_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.0e-63	100.0
WP_000975096.1\|1312684_1313263_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000683137.1\|1313259_1313655_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	3.7e-65	92.4
WP_032325228.1\|1313662_1314415_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.3e-130	95.6
WP_000479045.1\|1314428_1314851_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	1.7e-71	98.6
WP_000533440.1\|1314877_1315291_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_000081793.1\|1315271_1317884_+\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	91.1
WP_000847280.1\|1317880_1318210_+\|tail	phage tail protein	S5MW28	Escherichia_phage	1.2e-58	99.1
WP_032284485.1\|1318209_1318908_+\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	4.9e-129	96.1
WP_106875410.1\|1318918_1319662_+\|tail	phage tail protein	Q9EYE4	Enterobacteria_phage	4.4e-144	95.1
WP_123058126.1\|1319607_1320240_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	2.9e-104	93.3
WP_106875412.1\|1320475_1323952_+	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	97.2
WP_001230429.1\|1324018_1324618_+	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	2.3e-111	99.0
WP_094282965.1\|1324682_1325996_+\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	2.8e-77	98.9
WP_001023998.1\|1325997_1326267_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	2.3e-42	94.4
WP_122988840.1\|1326377_1326455_+	hypothetical protein	NA	NA	NA	NA
WP_122993102.1\|1326669_1327683_+	peptidase M85	NA	NA	NA	NA
WP_097451673.1\|1328136_1329293_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	7.5e-66	44.4

DBSCAN-SWA_8

1528796 : 1584896

Escherichia_phage(45.45%)

holin,tRNA,integrase,terminase,tail,capsid,portal,head

attL 1526508:1526522|attR 1584057:1584071

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1526508:1526522	attL	NA	NA	NA	NA
WP_000837924.1\|1528796_1529930_+	porin OmpN	Q1MVN1	Enterobacteria_phage	8.3e-118	58.8
WP_001295593.1\|1530070_1530505_+	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.4e-28	52.8
WP_001143784.1\|1531445_1532087_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	6.8e-109	100.0
WP_001443810.1\|1532168_1532798_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.3e-77	92.2
WP_001131657.1\|1532870_1533446_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	1.8e-89	88.9
WP_001023379.1\|1533558_1533828_-\|tail	phage tail protein	Q687E5	Enterobacteria_phage	8.7e-42	95.5
WP_106875415.1\|1533829_1535143_-\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	2.8e-77	97.3
WP_001233130.1\|1535207_1535807_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	1.8e-108	97.5
WP_106875416.1\|1535874_1539351_-	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	89.6
WP_123058126.1\|1539596_1540229_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	2.9e-104	93.3
WP_024236318.1\|1540174_1540918_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	1.9e-147	97.2
WP_106875417.1\|1540923_1541622_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	2.6e-130	97.0
WP_000847304.1\|1541621_1541951_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	2.2e-55	95.4
WP_000082320.1\|1541947_1544527_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	82.3
WP_000533431.1\|1544507_1544921_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.0e-41	82.8
WP_000479086.1\|1544947_1545379_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	4.8e-42	68.1
WP_106875418.1\|1545392_1546145_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.4e-128	94.0
WP_000683137.1\|1546152_1546548_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	3.7e-65	92.4
WP_106875419.1\|1546544_1547123_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.7e-79	99.0
WP_000752994.1\|1547134_1547488_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.0e-63	100.0
WP_000158897.1\|1547499_1547895_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.4e-56	93.9
WP_000063258.1\|1547936_1548962_-\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	5.1e-191	98.8
WP_001365129.1\|1549017_1549350_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.5e-54	98.2
WP_000123251.1\|1549359_1550679_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	7.6e-232	97.9
WP_024026143.1\|1550659_1552261_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	2.1e-308	98.9
WP_000198153.1\|1552257_1552464_-\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001027379.1\|1552460_1554386_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.1
WP_032284653.1\|1554360_1554906_-\|terminase	terminase small subunit	A0A0K2FIG2	Enterobacteria_phage	4.3e-80	83.4
WP_001300236.1\|1555300_1555525_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	2.9e-19	88.7
WP_001303878.1\|1555606_1555921_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_012816791.1\|1556448_1556634_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000675931.1\|1556855_1556969_-	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_000992045.1\|1557189_1557723_-	lysozyme	B6DZ92	Enterobacteria_phage	8.1e-100	96.6
WP_071528021.1\|1557834_1558095_+	hypothetical protein	NA	NA	NA	NA
WP_000193281.1\|1558042_1558594_-	YdfR family protein	K7PGU6	Enterobacteria_phage	2.3e-36	94.0
WP_000411802.1\|1558598_1558805_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000143050.1\|1559252_1561103_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	99.0
WP_000762928.1\|1562273_1563095_-	antitermination protein	K7P7B9	Enterobacteria_phage	4.1e-82	61.2
WP_001217413.1\|1563091_1563466_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.4e-34	63.6
WP_001341382.1\|1564530_1564809_-	hypothetical protein	I6PCV7	Cronobacter_phage	1.6e-11	46.9
WP_000018421.1\|1564976_1565189_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	8.1e-27	92.9
WP_001278454.1\|1565378_1565483_-	hypothetical protein	NA	NA	NA	NA
WP_000207986.1\|1565598_1566468_-	DUF551 domain-containing protein	A0A1U9AJ59	Stx1_converting_phage	5.2e-120	76.8
WP_000224233.1\|1566478_1566742_-	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
WP_042350895.1\|1566743_1566908_-	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	2.0e-17	90.7
WP_000935420.1\|1566993_1567206_-	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.8e-33	94.3
WP_000403777.1\|1567256_1567613_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	3.0e-58	98.3
WP_001209480.1\|1567590_1568052_-	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	3.4e-38	92.9
WP_001266134.1\|1568048_1568345_-	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	3.4e-47	94.7
WP_001151124.1\|1568341_1568764_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.0e-64	92.8
WP_000450674.1\|1568779_1569541_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	7.0e-121	90.5
WP_000788968.1\|1569563_1570310_-	ATP-binding protein	V5UQI5	Shigella_phage	2.4e-110	78.5
WP_000899746.1\|1570316_1571174_-	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	8.3e-70	84.5
WP_000693802.1\|1571186_1571609_-	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	6.9e-70	95.7
WP_001072343.1\|1571605_1571860_-	hypothetical protein	A0A2I6PIE5	Escherichia_phage	1.3e-18	61.6
WP_000233320.1\|1571939_1572359_+	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	4.2e-19	47.5
WP_001427316.1\|1572657_1572810_+	DUF1391 family protein	M4QQ57	Salicola_phage	2.3e-07	55.3
WP_000560223.1\|1573230_1573452_+	killing protein KilR	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
WP_001352098.1\|1573451_1573622_+	conserved protein, Rac prophage	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
WP_000632297.1\|1573696_1573972_+	protein RacC	A0A0U2QW85	Escherichia_phage	1.4e-42	96.7
WP_000105150.1\|1574073_1576674_+	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	3.0e-248	63.4
WP_000166313.1\|1576666_1577476_+	recombination protein RecT	A0A1P8DTF2	Proteus_phage	4.0e-106	71.5
WP_001443846.1\|1577531_1577681_+	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	2.5e-22	95.9
WP_001302840.1\|1577718_1577907_+	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	5.5e-27	98.4
WP_000079604.1\|1578006_1578222_+	excisionase XisR	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
WP_000040851.1\|1578223_1579459_+\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	3.0e-238	98.3
WP_001157401.1\|1579510_1580446_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	1.1e-144	98.4
WP_000123745.1\|1580574_1581948_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
WP_000387388.1\|1582425_1583409_-	zinc transporter ZntB	NA	NA	NA	NA
WP_000628065.1\|1583663_1584896_+	diguanylate cyclase DgcM	A0A127AWB9	Bacillus_phage	3.1e-17	39.5
1584057:1584071	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1661438 : 1737525

Stx2-converting_phage(38.46%)

protease,holin,integrase,terminase,transposase,tail,capsid,head

attL 1675217:1675244|attR 1737662:1737689

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000422045.1\|1661438_1662488_-\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5
WP_000559281.1\|1662707_1663466_+	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	24.5
WP_001278906.1\|1663462_1664053_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_001291216.1\|1664092_1664965_-	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001342101.1\|1665065_1665686_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001285661.1\|1665682_1666564_-	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001700591.1\|1666701_1666746_+	trp operon leader peptide	NA	NA	NA	NA
WP_001194584.1\|1666837_1668400_+	anthranilate synthase component I	NA	NA	NA	NA
WP_000763511.1\|1668399_1669995_+	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
WP_001342102.1\|1669998_1671357_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	1.5e-36	40.3
WP_000209520.1\|1671368_1672562_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_000443067.1\|1672561_1673368_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000807651.1\|1673748_1673928_+	general stress protein	NA	NA	NA	NA
WP_001056491.1\|1674013_1674514_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001079509.1\|1674559_1675066_+	ferritin-like domain-containing protein	NA	NA	NA	NA
1675217:1675244	attL	NA	NA	NA	NA
WP_000147167.1\|1675567_1675786_+	hypothetical protein	NA	NA	NA	NA
WP_001144877.1\|1678548_1679139_-	T3SS effector guanine nucleotide exchange factor EspM1	NA	NA	NA	NA
WP_001303944.1\|1679322_1679970_+	T3SS effector E3 ubiquitin-protein ligase NleG	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
WP_001414184.1\|1680106_1680253_-	hypothetical protein	NA	NA	NA	NA
WP_001303943.1\|1680680_1680959_+	hypothetical protein	NA	NA	NA	NA
WP_000938103.1\|1682126_1682696_-	T3SS effector caspase inhibitor NleF	NA	NA	NA	NA
WP_000950979.1\|1682761_1683673_-	type III secretion system effector kinase NleH1-2	A5LH48	Enterobacteria_phage	3.0e-134	82.2
WP_106409364.1\|1683779_1683902_-	hypothetical protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
WP_001023357.1\|1687847_1688117_-\|tail	phage tail protein	A0A2R2Z347	Escherichia_phage	3.8e-45	100.0
WP_001339397.1\|1688177_1688855_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|1688854_1689202_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381395.1\|1689221_1690793_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000216552.1\|1690825_1692139_-\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	6.9e-76	98.4
WP_001228278.1\|1692290_1692890_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	5.9e-107	95.5
WP_000902073.1\|1692957_1694007_-	DUF1983 domain-containing protein	Q9EYE7	Enterobacteria_phage	4.5e-195	100.0
WP_000099160.1\|1694029_1695568_-\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_000612626.1\|1695616_1695964_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839170.1\|1695960_1696365_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	2.5e-69	99.3
WP_158707426.1\|1699235_1699868_-\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	4.3e-92	90.4
WP_000194723.1\|1699813_1700557_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	5.0e-148	98.0
WP_001335877.1\|1700567_1701266_-\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	1.7e-129	96.6
WP_000807940.1\|1701265_1701607_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
WP_097453978.1\|1701599_1704842_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	89.7
WP_001513217.1\|1704889_1705099_-	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	1.5e-33	100.0
WP_000710952.1\|1705194_1705569_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_058157545.1\|1705583_1706300_-\|tail	phage tail protein	B6DZA6	Enterobacteria_phage	3.0e-121	95.8
WP_000133388.1\|1706365_1706710_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573391.1\|1706706_1707153_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007905.1\|1707149_1707500_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125984.1\|1707510_1707837_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
WP_001063025.1\|1710201_1710423_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_106875421.1\|1710467_1712405_-\|capsid	phage major capsid protein	A0A0P0ZAJ3	Stx2-converting_phage	0.0e+00	98.6
WP_106875422.1\|1712468_1714130_-\|terminase	terminase large subunit	A0A0P0ZEI4	Stx2-converting_phage	0.0e+00	98.7
WP_000958380.1\|1714126_1714690_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_000829192.1\|1714978_1715344_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
WP_001428130.1\|1715385_1715571_+	YlcI/YnfO family protein	H6WZK6	Escherichia_phage	1.3e-20	92.3
WP_000347013.1\|1715700_1715841_-	hypothetical protein	NA	NA	NA	NA
WP_000735655.1\|1716197_1716422_-	hypothetical protein	NA	NA	NA	NA
WP_001208682.1\|1716486_1716693_-	hypothetical protein	H6WRZ6	Salmonella_phage	7.1e-12	64.7
WP_000539792.1\|1716920_1717067_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|1717066_1717636_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992092.1\|1717906_1718440_-	lysozyme	B6DZ92	Enterobacteria_phage	2.5e-101	98.9
WP_000731221.1\|1718490_1718835_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.8e-55	95.6
WP_000284522.1\|1718839_1719055_-\|holin	holin	Q6H9V8	Enterobacteria_phage	1.3e-32	97.2
WP_000023141.1\|1719204_1721058_-	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	96.6
WP_032284729.1\|1722582_1723272_-	antiterminator	I6PDF8	Cronobacter_phage	5.3e-59	51.1
WP_000140002.1\|1723268_1723634_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	67.5
WP_001265290.1\|1723634_1724690_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.9e-88	47.6
WP_010917803.1\|1724691_1724970_-	hypothetical protein	I6PCV7	Cronobacter_phage	2.2e-11	48.4
WP_001217394.1\|1725039_1725297_-	hypothetical protein	NA	NA	NA	NA
WP_000961821.1\|1725517_1725730_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.3e-16	72.9
WP_001449026.1\|1726008_1726767_-	AcfC family adhesin Paa	NA	NA	NA	NA
WP_001505071.1\|1727465_1727630_-	hypothetical protein	NA	NA	NA	NA
WP_157825328.1\|1728393_1728936_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.5e-85	98.7
WP_000020556.1\|1728847_1729888_-	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_000705622.1\|1729859_1730411_-	hypothetical protein	NA	NA	NA	NA
WP_000912298.1\|1730394_1730622_-	transcriptional regulator	NA	NA	NA	NA
WP_000787428.1\|1730698_1731106_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	9.8e-29	49.6
WP_001240336.1\|1731370_1731670_+	hypothetical protein	NA	NA	NA	NA
WP_001171903.1\|1731742_1731961_+	hypothetical protein	NA	NA	NA	NA
WP_032277386.1\|1732369_1732603_-	hypothetical protein	NA	NA	NA	NA
WP_001342117.1\|1732596_1732764_-	hypothetical protein	NA	NA	NA	NA
WP_000449172.1\|1733163_1733352_+	cell division inhibitor	NA	NA	NA	NA
WP_000199480.1\|1733348_1733537_+	DUF1482 family protein	NA	NA	NA	NA
WP_000048478.1\|1733632_1736104_+	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.2
WP_000113189.1\|1736168_1736417_+	excisionase	NA	NA	NA	NA
WP_000113674.1\|1736394_1737525_+\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	3.4e-103	51.4
1737662:1737689	attR	NA	NA	NA	NA

DBSCAN-SWA_10

1841609 : 1857817

uncultured_Caudovirales_phage(90.0%)

protease,tRNA,terminase,capsid,portal,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001297484.1\|1841609_1842716_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_001297479.1\|1842751_1843393_+	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000423729.1\|1843396_1844767_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
WP_001265481.1\|1844934_1845606_+	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000735412.1\|1845605_1847066_+	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_000133415.1\|1847681_1847963_-	hypothetical protein	NA	NA	NA	NA
WP_000127884.1\|1847976_1849638_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	2.2e-276	81.2
WP_000113646.1\|1849621_1849978_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	3.6e-51	80.5
WP_001145906.1\|1850266_1850707_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	1.9e-62	73.3
WP_000134114.1\|1850706_1851003_-	hypothetical protein	A0A2H4JD08	uncultured_Caudovirales_phage	2.4e-32	65.3
WP_001020669.1\|1850999_1851338_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	1.7e-31	53.6
WP_001398592.1\|1851334_1852510_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	4.8e-185	80.2
WP_000504047.1\|1852547_1853120_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	1.6e-61	63.5
WP_001137338.1\|1853159_1854317_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	8.1e-137	64.6
WP_001132080.1\|1854608_1854833_-	hypothetical protein	NA	NA	NA	NA
WP_000233311.1\|1854958_1855231_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_000126670.1\|1855243_1855654_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_001368652.1\|1855663_1855852_-	hypothetical protein	NA	NA	NA	NA
WP_001080642.1\|1855965_1856217_-	hypothetical protein	NA	NA	NA	NA
WP_000833614.1\|1856419_1857817_-	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	4.3e-116	49.0

DBSCAN-SWA_11

1861249 : 1936393

Enterobacteria_phage(24.29%)

holin,protease,integrase,terminase,lysis,tail,capsid,head

attL 1865486:1865500|attR 1936941:1936955

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000085269.1\|1861249_1862479_-\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.1e-131	55.6
WP_000456506.1\|1862727_1863849_+	cupin domain-containing protein	NA	NA	NA	NA
WP_000359438.1\|1863994_1865224_-	peptidase T	NA	NA	NA	NA
WP_000531601.1\|1865473_1866610_+	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	9.4e-29	39.8
1865486:1865500	attL	NA	NA	NA	NA
WP_000799399.1\|1866593_1867457_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_001132165.1\|1867730_1868321_-	bfpT-regulated chaperone	NA	NA	NA	NA
WP_001144080.1\|1868503_1869154_+	T3SS effector NleG family protein	B6DZZ5	Stx2-converting_phage	2.8e-25	37.2
WP_001299273.1\|1869228_1870287_+	T3SS effector EspW	NA	NA	NA	NA
WP_012816780.1\|1870414_1871050_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	3.7e-75	92.0
WP_001118085.1\|1871117_1871699_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	2.7e-48	54.8
WP_001131642.1\|1871989_1872565_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	4.1e-57	60.5
WP_001023435.1\|1872678_1872948_-\|tail	phage tail protein	Q9EYE9	Enterobacteria_phage	2.4e-44	97.8
WP_044723507.1\|1872949_1874263_-\|tail	tail fiber protein	H6WZM9	Escherichia_phage	2.8e-77	98.2
WP_001216290.1\|1874328_1874952_-	Ail/Lom family outer membrane beta-barrel protein	A0A1U8QHD6	Enterobacteria_phage	1.1e-68	60.4
WP_106875424.1\|1875020_1878497_-	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	96.8
WP_158707427.1\|1878742_1879375_-\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	6.7e-93	91.4
WP_000194723.1\|1879320_1880064_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	5.0e-148	98.0
WP_001335877.1\|1880074_1880773_-\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	1.7e-129	96.6
WP_000807940.1\|1880772_1881114_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
WP_000212980.1\|1881106_1884349_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	92.0
WP_001513217.1\|1884396_1884606_-	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	1.5e-33	100.0
WP_000710952.1\|1884701_1885076_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_058157545.1\|1885090_1885807_-\|tail	phage tail protein	B6DZA6	Enterobacteria_phage	3.0e-121	95.8
WP_000133388.1\|1885873_1886218_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573374.1\|1886214_1886661_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_001007905.1\|1886657_1887008_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125988.1\|1887017_1887344_-\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_001063025.1\|1889795_1890017_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_106875421.1\|1890061_1891999_-\|capsid	phage major capsid protein	A0A0P0ZAJ3	Stx2-converting_phage	0.0e+00	98.6
WP_106875426.1\|1892062_1893724_-\|terminase	terminase large subunit	A0A0P0ZEI4	Stx2-converting_phage	0.0e+00	98.9
WP_000958380.1\|1893720_1894284_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_001427183.1\|1894576_1894942_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	9.9e-65	97.5
WP_000095736.1\|1894983_1895211_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_000736096.1\|1895579_1895804_-	hypothetical protein	NA	NA	NA	NA
WP_001427182.1\|1895800_1896295_-\|lysis	lysis protein	Q7AYI6	Enterobacteria_phage	1.4e-74	97.4
WP_032140280.1\|1896296_1896383_-	hypothetical protein	NA	NA	NA	NA
WP_001003120.1\|1896937_1897471_-	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.6e-100	94.9
WP_000138558.1\|1897630_1897903_+	hypothetical protein	NA	NA	NA	NA
WP_000411814.1\|1898158_1898365_-\|holin	holin	Q6H9V8	Enterobacteria_phage	5.3e-31	98.5
WP_000874393.1\|1898812_1900663_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	95.8
WP_000261909.1\|1901430_1902144_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001303877.1\|1902238_1902478_-	hypothetical protein	Q9MC00	Enterobacteria_phage	7.7e-18	98.0
WP_000265267.1\|1902764_1903583_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000090264.1\|1903734_1904106_-	antitermination protein	Q777W5	Enterobacteria_phage	4.0e-53	83.2
WP_001217436.1\|1904095_1904467_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_001265140.1\|1904479_1905529_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	3.4e-110	54.6
WP_001341388.1\|1905530_1905809_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001013636.1\|1905976_1906189_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	8.9e-26	96.9
WP_000955173.1\|1906233_1906371_+	hypothetical protein	Q7Y2Q9	Escherichia_phage	5.4e-08	96.6
WP_000160654.1\|1906736_1907510_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_106875427.1\|1907861_1908275_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	3.7e-60	88.3
WP_000450992.1\|1908290_1909061_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	6.1e-80	64.5
WP_000788750.1\|1909082_1909829_-	ATP-binding protein	A0A088CBP4	Shigella_phage	4.0e-113	83.8
WP_001205823.1\|1909835_1910927_-	hypothetical protein	V5URT9	Shigella_phage	5.1e-133	70.0
WP_000273724.1\|1911005_1911461_+	hypothetical protein	NA	NA	NA	NA
WP_000693855.1\|1911666_1912092_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000887453.1\|1912075_1912348_-	hypothetical protein	A0A0U2S629	Escherichia_phage	1.1e-12	45.8
WP_000986592.1\|1912456_1912858_+	helix-turn-helix domain-containing protein	A0A1B5FPF4	Escherichia_phage	7.4e-13	54.5
WP_000536233.1\|1912885_1913077_+	hypothetical protein	NA	NA	NA	NA
WP_001303876.1\|1913076_1913364_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000379575.1\|1913640_1913796_+	DUF1391 family protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_000394511.1\|1913937_1914327_+	hypothetical protein	NA	NA	NA	NA
WP_001133046.1\|1914513_1914699_-	hypothetical protein	NA	NA	NA	NA
WP_000413705.1\|1915272_1915461_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001098307.1\|1915457_1915649_+	DUF1482 family protein	NA	NA	NA	NA
WP_032278809.1\|1915742_1918214_+	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	56.6
WP_000273151.1\|1918281_1918524_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_001299351.1\|1918501_1919521_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.3e-85	49.7
WP_001427258.1\|1920337_1920769_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	6.2e-66	96.5
WP_000762928.1\|1921334_1922156_-	antitermination protein	K7P7B9	Enterobacteria_phage	4.1e-82	61.2
WP_001217410.1\|1922152_1922527_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.1e-33	62.7
WP_106875428.1\|1922539_1923589_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	2.2e-109	54.3
WP_000191872.1\|1923590_1923863_-	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_000756596.1\|1923984_1924329_-	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_001013638.1\|1924448_1924661_-	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	3.1e-26	100.0
WP_000104474.1\|1924894_1925452_-	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
WP_000683607.1\|1925453_1925672_-	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	6.2e-22	73.6
WP_001365112.1\|1925774_1926110_-	hypothetical protein	A0A0U2QV73	Escherichia_phage	2.0e-48	91.4
WP_000699809.1\|1926102_1926330_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
WP_000603384.1\|1926326_1926608_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
WP_032284689.1\|1926640_1927402_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.9e-73	62.9
WP_000788758.1\|1927423_1928170_-	ATP-binding protein	A0A088CBP4	Shigella_phage	9.0e-113	83.4
WP_001262372.1\|1928176_1929247_-	hypothetical protein	A0A088CD36	Shigella_phage	4.5e-65	66.2
WP_000693928.1\|1929318_1929744_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000711018.1\|1929727_1930051_-	transcriptional regulator	A0A0R6PH31	Moraxella_phage	6.2e-10	44.9
WP_000948454.1\|1930175_1930652_+	hypothetical protein	A0A2D1GNH0	Pseudomonas_phage	5.7e-12	53.4
WP_000379610.1\|1930970_1931123_+	DUF1391 family protein	M4QQ57	Salicola_phage	8.7e-07	51.1
WP_001358566.1\|1931612_1931801_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001365098.1\|1931797_1931989_+\|lysis	lysis protein YdfD	NA	NA	NA	NA
WP_000048279.1\|1932082_1934554_+	exonuclease	K7PLW7	Enterobacteria_phage	8.5e-59	60.3
WP_000003742.1\|1934615_1934885_+	excisionase	NA	NA	NA	NA
WP_000074973.1\|1934853_1935972_+\|integrase	tyrosine-type recombinase/integrase	Q77Z04	Phage_21	2.0e-84	44.4
WP_001427255.1\|1936048_1936393_-	DUF2335 domain-containing protein	A0A1B0YZW3	Pseudomonas_phage	1.9e-09	34.7
1936941:1936955	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2105736 : 2283055

210

Escherichia_phage(31.13%)

holin,protease,integrase,terminase,transposase,tail,capsid,head

attL 2229166:2229225|attR 2282130:2282194

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000998025.1\|2105736_2107269_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	7.1e-298	99.6
WP_000233452.1\|2108025_2110386_-	DEAD/DEAH box helicase family protein	Q84473	Paramecium_bursaria_Chlorella_virus	1.8e-34	32.5
WP_000282084.1\|2110540_2111104_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_000335695.1\|2111924_2113358_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_000579535.1\|2113576_2113774_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_001303889.1\|2114000_2114297_-	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_096949893.1\|2115408_2117226_+	hypothetical protein	NA	NA	NA	NA
WP_000279872.1\|2117412_2118615_-\|integrase	tyrosine-type recombinase/integrase	A0A1B0VMI6	Pseudomonas_phage	2.9e-44	34.4
WP_001297190.1\|2119240_2119696_-	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_001307105.1\|2120507_2121431_-	phosphate starvation-inducible protein PhoH	R4II13	Cronobacter_phage	9.2e-91	76.7
WP_001199164.1\|2121914_2123186_-	deferrochelatase/peroxidase EfeB	NA	NA	NA	NA
WP_000154411.1\|2123191_2124319_-	iron uptake system protein EfeO	NA	NA	NA	NA
WP_000497942.1\|2124376_2125207_-	FTR1 family protein	NA	NA	NA	NA
WP_001018496.1\|2125872_2127381_-	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000979516.1\|2127539_2127749_-	hypothetical protein	NA	NA	NA	NA
WP_001341463.1\|2127803_2131766_+	trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000191700.1\|2131805_2132444_-	HTH-type transcriptional regulator RutR	NA	NA	NA	NA
WP_001297176.1\|2132731_2133823_+	pyrimidine utilization protein A	NA	NA	NA	NA
WP_001307708.1\|2133822_2134515_+	peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB	NA	NA	NA	NA
WP_021534122.1\|2134526_2134913_+	pyrimidine utilization protein C	NA	NA	NA	NA
WP_001341462.1\|2134920_2135721_+	pyrimidine utilization protein D	NA	NA	NA	NA
WP_001001171.1\|2135730_2136321_+	malonic semialdehyde reductase	NA	NA	NA	NA
WP_001028095.1\|2136331_2136826_+	pyrimidine utilization flavin reductase protein F	Q9KX93	Enterobacteria_phage	5.0e-51	97.9
WP_001240628.1\|2136846_2138175_+	pyrimidine utilization transport protein G	Q9KX94	Enterobacteria_phage	1.0e-231	98.4
WP_001273658.1\|2138257_2138431_-	general stress protein	Q9KX95	Enterobacteria_phage	4.9e-06	96.3
WP_001151437.1\|2138803_2139400_+	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_001143120.1\|2139420_2139648_+	hypothetical protein	NA	NA	NA	NA
WP_001044313.1\|2139685_2140927_-	bifunctional glucose-1-phosphatase/inositol phosphatase	NA	NA	NA	NA
WP_000097601.1\|2141218_2142478_-	YccE family protein	NA	NA	NA	NA
WP_000420629.1\|2142737_2143658_+	curved DNA-binding protein	A0A1V0SIM1	Klosneuvirus	3.2e-11	43.0
WP_000024561.1\|2143657_2143963_+	chaperone modulator CbpM	NA	NA	NA	NA
WP_000209869.1\|2144055_2144655_-	molecular chaperone TorD	NA	NA	NA	NA
WP_001062101.1\|2144651_2147198_-	trimethylamine-N-oxide reductase TorA	A0A077SK27	Escherichia_phage	1.0e-70	29.2
WP_001230242.1\|2147197_2148370_-	pentaheme c-type cytochrome TorC	NA	NA	NA	NA
WP_001120112.1\|2148499_2149192_+	two-component system response regulator TorR	W8CYM9	Bacillus_phage	4.5e-18	28.0
WP_001264955.1\|2149164_2150193_-	TMAO reductase system periplasmic protein TorT	NA	NA	NA	NA
WP_001121564.1\|2150664_2151318_+	EspJ family T3SS effector ADP-ribosyltransferase	NA	NA	NA	NA
WP_001002867.1\|2151330_2152029_-	hypothetical protein	NA	NA	NA	NA
WP_001131653.1\|2152229_2152811_-	T3SS effector NleG family protein	H6WZN1	Escherichia_phage	5.1e-63	64.2
WP_106420821.1\|2152801_2152996_-	hypothetical protein	A0A2R2Z347	Escherichia_phage	4.1e-09	84.6
WP_000767050.1\|2152940_2153483_-	hypothetical protein	Q9LA55	Enterobacteria_phage	8.4e-52	68.6
WP_001023995.1\|2153704_2153974_-\|tail	phage tail protein	A0A0P0ZCV7	Stx2-converting_phage	7.1e-44	95.5
WP_000279023.1\|2153975_2155190_-	short-chain dehydrogenase	B6DZB7	Enterobacteria_phage	6.6e-81	95.8
WP_001230429.1\|2155254_2155854_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	2.3e-111	99.0
WP_106875429.1\|2155920_2159397_-	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	97.2
WP_096844540.1\|2159632_2160265_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-102	91.8
WP_106875431.1\|2160210_2160954_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	4.1e-150	99.6
WP_001357740.1\|2160964_2161663_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	8.1e-132	98.7
WP_000807964.1\|2161662_2162004_-\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
WP_106875432.1\|2161996_2165239_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	94.8
WP_122993730.1\|2165289_2165499_-	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	2.6e-30	92.8
WP_000710952.1\|2165594_2165969_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_001275441.1\|2165983_2166700_-\|tail	tail protein	A0A0P0ZDV1	Stx2-converting_phage	3.6e-127	99.6
WP_000133393.1\|2166766_2167111_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_000573391.1\|2167107_2167554_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007905.1\|2167550_2167901_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125988.1\|2167910_2168237_-\|head,tail	phage gp6-like head-tail connector protein	B6ETF0	Enterobacteria_phage	7.0e-54	100.0
WP_001063096.1\|2170601_2170823_-	hypothetical protein	H6WZL1	Escherichia_phage	3.4e-36	100.0
WP_106875433.1\|2170867_2172805_-\|capsid	phage major capsid protein	A0A0P0ZCT9	Stx2-converting_phage	0.0e+00	99.1
WP_001399867.1\|2172868_2174530_-\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.6
WP_000958380.1\|2174526_2175090_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_000829192.1\|2175378_2175744_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
WP_032277401.1\|2175785_2175986_+	YlcI/YnfO family protein	H6WZK6	Escherichia_phage	2.8e-29	95.5
WP_000828068.1\|2176117_2176444_-	TonB family protein	H6WZK5	Escherichia_phage	1.5e-56	99.1
WP_001109019.1\|2176789_2177341_-	Rha family transcriptional regulator	A0A0P0ZFJ1	Escherichia_phage	4.5e-101	100.0
WP_071529499.1\|2177579_2177765_-	hypothetical protein	A0A0P0ZCT3	Stx2-converting_phage	1.3e-17	96.7
WP_001280922.1\|2177987_2178119_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	8.5e-11	90.7
WP_000661712.1\|2178213_2178909_-	phage antirepressor protein	Q5MBW0	Stx1-converting_phage	2.8e-124	99.1
WP_000087733.1\|2179182_2179716_-	lysozyme	G9L6J6	Escherichia_phage	1.0e-102	100.0
WP_001072901.1\|2179720_2179936_-\|holin	holin	A0A2R2Z340	Escherichia_phage	1.2e-33	100.0
WP_001290230.1\|2180013_2180259_-	DUF826 domain-containing protein	A0A0P0ZGR2	Escherichia_phage	8.8e-17	100.0
WP_000143463.1\|2180299_2180479_-	DUF1378 family protein	Q5MBW3	Stx1-converting_phage	4.4e-26	100.0
WP_000142995.1\|2180614_2182552_-	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	0.0e+00	99.7
WP_000752026.1\|2183051_2183321_-	Shiga toxin Stx1a subunit B	Q7AYI7	Enterobacteria_phage	1.6e-43	100.0
WP_000691354.1\|2183330_2184278_-	Shiga toxin Stx1 subunit A	Q777W4	Enterobacteria_phage	3.2e-171	100.0
WP_001204852.1\|2184784_2185219_-	antitermination protein	Q777W5	Enterobacteria_phage	3.6e-82	100.0
WP_000144759.1\|2185211_2185406_-	protein ninH	Q6H9W6	Enterobacteria_phage	8.4e-31	100.0
WP_001107963.1\|2185402_2186008_-	recombination protein NinG	A0A0P0ZCS9	Stx2-converting_phage	1.7e-98	100.0
WP_001004024.1\|2186007_2186730_-	DNA-binding protein	A0A0N7C231	Escherichia_phage	7.8e-130	100.0
WP_000211422.1\|2186804_2187539_-	phage antirepressor Ant	A0A0N7C203	Escherichia_phage	1.9e-123	100.0
WP_001254256.1\|2187813_2187996_-	NinE family protein	A0A0N7C1X3	Escherichia_phage	5.7e-29	100.0
WP_000153280.1\|2187992_2188520_-	phage N-6-adenine-methyltransferase	A0A1I9LJP9	Stx_converting_phage	9.5e-101	100.0
WP_000814576.1\|2188516_2188963_-	recombination protein NinB	A0A0N7C2V1	Escherichia_phage	2.4e-81	100.0
WP_001281772.1\|2188919_2189156_-	restriction alleviation protein, Lar family	Q8HA09	Enterobacteria_phage	1.2e-39	100.0
WP_000103679.1\|2189166_2189382_-	hypothetical protein	A0A1I9LJP7	Stx_converting_phage	1.3e-32	100.0
WP_001000127.1\|2189514_2189793_-	hypothetical protein	Q9ZWY1	Enterobacteria_phage	3.4e-49	100.0
WP_000145907.1\|2189863_2190154_-	protein ren	A0A0N6WES4	Escherichia_phage	1.6e-46	99.0
WP_000788839.1\|2190150_2190852_-	Replication protein P	Q6H9X6	Enterobacteria_phage	4.5e-130	100.0
WP_000185456.1\|2190848_2191787_-	replication protein	C1JJ53	Enterobacteria_phage	2.8e-172	100.0
WP_000438542.1\|2191819_2192116_-	hypothetical protein	Q6H9X8	Enterobacteria_phage	5.2e-48	100.0
WP_001180318.1\|2192254_2192482_-	transcriptional regulator	G9L677	Escherichia_phage	7.8e-36	100.0
WP_000250473.1\|2192560_2193268_+	helix-turn-helix transcriptional regulator	G9L676	Escherichia_phage	1.5e-133	100.0
WP_001133195.1\|2193437_2194340_+	hypothetical protein	A4KWU2	Enterobacteria_phage	2.2e-150	86.5
WP_000198444.1\|2194851_2195235_+	hypothetical protein	G9L671	Escherichia_phage	3.9e-64	100.0
WP_000248817.1\|2195445_2195760_+	hypothetical protein	A0A1I9LJN4	Stx_converting_phage	2.3e-54	99.0
WP_000065373.1\|2195910_2196279_+	DUF2528 family protein	M1FPD2	Enterobacteria_phage	7.6e-65	99.2
WP_001198858.1\|2196351_2196492_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q776Q5	Enterobacteria_phage	3.3e-21	100.0
WP_000361826.1\|2196484_2196628_+	host cell division inhibitory peptide Kil	A0A0P0ZC96	Stx2-converting_phage	3.5e-18	97.9
WP_000995407.1\|2196703_2197000_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	5.2e-48	98.0
WP_000100847.1\|2197005_2197791_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000186781.1\|2197787_2198468_+	YqaJ viral recombinase family protein	A0A0P0ZCQ7	Stx2-converting_phage	6.0e-132	99.1
WP_000682304.1\|2198464_2198647_+	DUF1317 domain-containing protein	A0A0P0ZD61	Stx2-converting_phage	7.4e-29	100.0
WP_000548528.1\|2198619_2198811_+	DUF1382 family protein	A0A0P0ZC60	Stx2-converting_phage	5.6e-27	100.0
WP_001386642.1\|2198821_2199103_+	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	5.5e-47	98.9
WP_000763378.1\|2199201_2199423_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	8.4e-35	97.3
WP_001289864.1\|2199419_2199827_+	ead/Ea22-like family protein	A0A125RPT9	Escherichia_phage	2.8e-68	97.8
WP_000582235.1\|2199828_2200584_+	hypothetical protein	A0A1R3Y5Q7	Salmonella_virus	7.1e-142	92.4
WP_000208003.1\|2200594_2201377_+	DUF550 domain-containing protein	K7PGV7	Enterobacterial_phage	1.1e-47	67.8
WP_000376716.1\|2201376_2201655_+	DUF4752 family protein	K7P6P7	Enterobacteria_phage	5.4e-47	98.9
WP_001368678.1\|2201812_2202112_+	hypothetical protein	Q9G076	Enterobacteria_phage	2.4e-53	100.0
WP_000545713.1\|2202147_2202315_+	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	1.2e-25	96.4
WP_001281197.1\|2202343_2202688_+	hypothetical protein	K7PJY7	Enterobacterial_phage	2.0e-59	99.1
WP_001303849.1\|2202805_2203024_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000533665.1\|2203001_2204075_+\|integrase	tyrosine-type recombinase/integrase	Q9G075	Enterobacteria_phage	2.0e-198	98.9
WP_001444338.1\|2204169_2206914_+	TMAO reductase system sensor histidine kinase/response regulator TorS	A0A1V0SGX0	Hokovirus	1.0e-36	31.9
WP_000818472.1\|2206985_2208059_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_001019197.1\|2208106_2208280_-	addiction module toxin, GnsA/GnsB family	NA	NA	NA	NA
WP_001316982.1\|2208269_2208500_-	protein YmcE	NA	NA	NA	NA
WP_071524879.1\|2208474_2208663_-	cold-shock protein	NA	NA	NA	NA
WP_000066490.1\|2208673_2208886_-	cold shock protein CspG	A0A1W6JNX5	Morganella_phage	7.8e-22	71.4
WP_000087763.1\|2209171_2209384_+	cold shock-like protein CspH	NA	NA	NA	NA
WP_001295358.1\|2209825_2210131_+	threonine-rich inner membrane protein GfcA	NA	NA	NA	NA
WP_001247610.1\|2210237_2210882_+	lipoprotein GfcB	NA	NA	NA	NA
WP_001038062.1\|2210878_2211625_+	capsule biosynthesis GfcC family protein	NA	NA	NA	NA
WP_000742348.1\|2211624_2213721_+	YjbH domain-containing protein	NA	NA	NA	NA
WP_001295357.1\|2213766_2214906_+	polysaccharide export protein	NA	NA	NA	NA
WP_000057871.1\|2214893_2215340_+	protein-tyrosine-phosphatase Etp	NA	NA	NA	NA
WP_032276985.1\|2215359_2217540_+	tyrosine-protein kinase	NA	NA	NA	NA
WP_001300464.1\|2217654_2218953_-	AppA family phytase/histidine-type acid phosphatase	NA	NA	NA	NA
WP_000399648.1\|2219216_2220197_+\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
WP_000270305.1\|2220311_2220404_-	cytochrome bd-II oxidase subunit CbdX	NA	NA	NA	NA
WP_000460810.1\|2220416_2221553_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_071527988.1\|2221564_2223061_-	cytochrome bd-II oxidase subunit 1	NA	NA	NA	NA
WP_000004899.1\|2223243_2224101_-	hydrogenase expression/formation protein	NA	NA	NA	NA
WP_000063972.1\|2224097_2224496_-	hydrogenase-1 operon protein HyaE	NA	NA	NA	NA
WP_000003671.1\|2224492_2225080_-\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA
WP_001186421.1\|2225076_2225784_-	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_000107384.1\|2225802_2227596_-	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_001058323.1\|2227592_2228711_-	hydrogenase 1 small subunit	NA	NA	NA	NA
2229166:2229225	attL	NA	NA	NA	NA
WP_095585410.1\|2229306_2229459_-\|tail	phage tail protein	K7PMH7	Enterobacteria_phage	4.3e-14	84.4
WP_000938124.1\|2229835_2231197_+	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	1.5e-49	40.2
WP_001023483.1\|2231651_2231921_-\|tail	phage tail protein	Q687E5	Enterobacteria_phage	1.2e-43	96.6
WP_000381395.1\|2231958_2233530_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|2233549_2233897_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|2233896_2234574_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_106875435.1\|2234623_2235943_-\|tail	phage tail protein	H6WZM9	Escherichia_phage	7.5e-78	98.4
WP_001230428.1\|2236007_2236607_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	1.4e-111	99.5
WP_096844540.1\|2240392_2241025_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-102	91.8
WP_001405642.1\|2240970_2241714_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	5.6e-147	97.6
WP_001335877.1\|2241724_2242423_-\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	1.7e-129	96.6
WP_000807940.1\|2242422_2242764_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
WP_097453978.1\|2242756_2245999_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	89.7
WP_001513217.1\|2246046_2246256_-	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	1.5e-33	100.0
WP_000710952.1\|2246351_2246726_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_058157545.1\|2246740_2247457_-\|tail	phage tail protein	B6DZA6	Enterobacteria_phage	3.0e-121	95.8
WP_000133388.1\|2247522_2247867_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573391.1\|2247863_2248310_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007905.1\|2248306_2248657_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000125984.1\|2248667_2248994_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
WP_001063025.1\|2251358_2251580_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_106875421.1\|2251624_2253562_-\|capsid	phage major capsid protein	A0A0P0ZAJ3	Stx2-converting_phage	0.0e+00	98.6
WP_106875426.1\|2253625_2255287_-\|terminase	terminase large subunit	A0A0P0ZEI4	Stx2-converting_phage	0.0e+00	98.9
WP_000958380.1\|2255283_2255847_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_001375434.1\|2256139_2256505_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	5.3e-66	99.2
WP_001448509.1\|2256546_2256771_+	YlcI/YnfO family protein	A0A0P0ZE23	Stx2-converting_phage	2.9e-19	76.1
WP_001302717.1\|2256852_2257167_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001208680.1\|2257692_2257878_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_000455402.1\|2258105_2258255_-	hypothetical protein	A0A0P0ZFU6	Escherichia_phage	9.1e-17	98.0
WP_001056883.1\|2258254_2258824_-	hypothetical protein	A0A2R2Z339	Escherichia_phage	1.5e-104	99.5
WP_106875436.1\|2259098_2259632_-	lysozyme	G9L6J6	Escherichia_phage	3.9e-102	98.9
WP_001072901.1\|2259636_2259852_-\|holin	holin	A0A2R2Z340	Escherichia_phage	1.2e-33	100.0
WP_001290230.1\|2259929_2260175_-	DUF826 domain-containing protein	A0A0P0ZGR2	Escherichia_phage	8.8e-17	100.0
WP_000143463.1\|2260215_2260395_-	DUF1378 family protein	Q5MBW3	Stx1-converting_phage	4.4e-26	100.0
WP_106875437.1\|2260530_2262468_-	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	0.0e+00	96.9
WP_000466957.1\|2262945_2263377_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
WP_000301785.1\|2263826_2264540_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000917770.1\|2264674_2264872_-	hypothetical protein	S5MQK8	Escherichia_phage	8.9e-28	96.9
WP_000640048.1\|2265113_2265644_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	9.3e-72	72.6
WP_000904103.1\|2265652_2266012_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.8e-34	60.0
WP_001265113.1\|2266024_2267071_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.4e-108	54.5
WP_001342259.1\|2267072_2267345_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.2e-10	47.5
WP_001260977.1\|2267480_2267738_+	type II toxin-antitoxin system ParD family antitoxin	A0A0N7C055	Escherichia_phage	1.5e-30	86.7
WP_000220601.1\|2267743_2268043_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2R2Z2Y1	Escherichia_phage	1.8e-51	100.0
WP_000206830.1\|2268247_2268592_-	hypothetical protein	A0A2R2Z2X8	Escherichia_phage	1.7e-58	100.0
WP_001229296.1\|2268588_2268954_-	HNH endonuclease	A0A2R2Z2X9	Escherichia_phage	5.1e-69	100.0
WP_000209152.1\|2268955_2269174_-	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	6.6e-32	100.0
WP_001289353.1\|2269261_2269897_-	ead/Ea22-like family protein	A0A2R2Z315	Escherichia_phage	1.3e-115	100.0
WP_001224662.1\|2270062_2270245_-	hypothetical protein	A0A2R2Z308	Escherichia_phage	1.4e-27	100.0
WP_000935422.1\|2270278_2270491_-	hypothetical protein	A0A2R2Z310	Escherichia_phage	6.6e-37	100.0
WP_000403783.1\|2270541_2270898_-	hypothetical protein	A0A2R2Z307	Escherichia_phage	4.6e-59	100.0
WP_001209480.1\|2270875_2271337_-	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	3.4e-38	92.9
WP_001266133.1\|2271333_2271630_-	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	5.8e-47	94.7
WP_001040234.1\|2271626_2272019_-	DUF977 family protein	A0A088CBK9	Shigella_phage	1.0e-38	62.6
WP_000450641.1\|2272034_2272760_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.2e-77	63.4
WP_072096947.1\|2272793_2273336_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.8e-78	89.5
WP_000729535.1\|2273247_2274258_-	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	4.9e-170	88.8
WP_000693932.1\|2274344_2274782_-	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	1.6e-29	55.0
WP_001172789.1\|2274778_2275039_-	transcriptional regulator	H6WRX5	Salmonella_phage	4.8e-21	64.8
WP_000578360.1\|2275165_2275558_+	helix-turn-helix domain-containing protein	H6WRX4	Salmonella_phage	1.7e-14	39.6
WP_001022415.1\|2275604_2275964_-	helix-turn-helix domain-containing protein	A0A222YXG1	Escherichia_phage	3.6e-59	93.3
WP_000692026.1\|2275966_2276269_-	type II toxin-antitoxin system HigB family toxin	A0A0P0ZE17	Stx2-converting_phage	3.7e-17	43.3
WP_024182289.1\|2276682_2276883_-	hypothetical protein	NA	NA	NA	NA
WP_001171921.1\|2276975_2277194_+	hypothetical protein	NA	NA	NA	NA
WP_001331716.1\|2277197_2277362_-	hypothetical protein	NA	NA	NA	NA
WP_000449175.1\|2277762_2277951_+	cell division inhibitor	NA	NA	NA	NA
WP_000199475.1\|2277947_2278136_+	DUF1482 family protein	NA	NA	NA	NA
WP_000048499.1\|2278230_2280681_+	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.6
WP_000273151.1\|2280748_2280991_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_001299351.1\|2280968_2281988_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.3e-85	49.7
WP_000375138.1\|2282395_2283055_+\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	5.2e-48	54.9
2282130:2282194	attR	NA	NA	NA	NA

DBSCAN-SWA_13

2539572 : 2623930

104

Enterobacteria_phage(45.21%)

holin,protease,integrase,terminase,lysis,transposase,tail,portal,head

attL 2540698:2540732|attR 2625364:2625398

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000399648.1\|2539572_2540553_+\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
2540698:2540732	attL	NA	NA	NA	NA
WP_001145128.1\|2540812_2541295_-	N-glycosidase YbiA	A0A0H3TLU0	Faustovirus	1.5e-36	52.7
WP_001218655.1\|2541414_2543565_+	ATP-dependent DNA helicase DinG	A0A127AW80	Bacillus_phage	4.8e-42	25.8
WP_000386551.1\|2543592_2544555_+	DNA-binding protein YbiB	NA	NA	NA	NA
WP_000443534.1\|2544695_2545781_+	malate/lactate/ureidoglycolate dehydrogenase	NA	NA	NA	NA
WP_000007094.1\|2546011_2547376_-	ATP-dependent RNA helicase RhlE	A0A1V0SBR7	Catovirus	1.5e-52	31.8
WP_001296991.1\|2547604_2548276_+	DNA-binding transcriptional regulator CecR	NA	NA	NA	NA
WP_001296990.1\|2548278_2549274_+	secretion protein HlyD	NA	NA	NA	NA
WP_000996091.1\|2549266_2551003_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.3e-18	30.3
WP_000070131.1\|2550995_2552129_+	ABC transporter permease	NA	NA	NA	NA
WP_000469031.1\|2552139_2553246_+	ABC transporter permease	NA	NA	NA	NA
WP_000871982.1\|2553207_2553618_-	hypothetical protein	NA	NA	NA	NA
WP_001113363.1\|2553750_2554512_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000650337.1\|2554508_2555750_+	cardiolipin synthase ClsB	NA	NA	NA	NA
WP_000045454.1\|2555749_2556706_+	UPF0104 family protein	NA	NA	NA	NA
WP_000446932.1\|2556741_2557455_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_000373624.1\|2557659_2558364_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_000852287.1\|2558500_2558953_-	molybdopterin synthase catalytic subunit MoaE	NA	NA	NA	NA
WP_000598619.1\|2558954_2559200_-	molybdopterin synthase sulfur carrier subunit	NA	NA	NA	NA
WP_000080885.1\|2559192_2559678_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_000084632.1\|2559680_2560193_-	molybdenum cofactor biosynthesis protein B	NA	NA	NA	NA
WP_001295301.1\|2560214_2561204_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_001295302.1\|2561600_2562509_+	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	1.4e-27	31.1
WP_000042533.1\|2562700_2564722_-	excinuclease ABC subunit B	NA	NA	NA	NA
WP_000044868.1\|2565300_2565978_-	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_000246805.1\|2565970_2566726_-	malonyl-ACP O-methyltransferase BioC	NA	NA	NA	NA
WP_000118840.1\|2566712_2567867_-	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_000951213.1\|2567863_2568904_-	biotin synthase BioB	NA	NA	NA	NA
WP_001443724.1\|2568990_2570280_+	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	1.0e-18	29.0
WP_000767389.1\|2570338_2570815_+	kinase inhibitor	NA	NA	NA	NA
WP_001121571.1\|2571318_2571972_+	type III secretion system effector ADP-ribosyltransferase EspJ	NA	NA	NA	NA
WP_000354291.1\|2571984_2572206_-	hypothetical protein	NA	NA	NA	NA
WP_001002868.1\|2572289_2572670_-	hypothetical protein	NA	NA	NA	NA
WP_001448642.1\|2572870_2573446_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	1.6e-77	77.5
WP_001339397.1\|2573506_2574184_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|2574183_2574531_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_106875440.1\|2574550_2576122_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	2.2e-169	58.5
WP_021351651.1\|2576596_2576968_+	hypothetical protein	K7PH54	Enterobacteria_phage	1.1e-58	95.1
WP_000652081.1\|2577091_2577919_-	type III secretion system effector Cif	A5LH49	Enterobacteria_phage	3.1e-154	98.2
WP_000950982.1\|2578142_2579024_-	hypothetical protein	A5LH48	Enterobacteria_phage	3.9e-147	90.4
WP_001023459.1\|2579129_2579399_-\|tail	phage tail protein	Q687E5	Enterobacteria_phage	4.6e-43	96.6
WP_032284503.1\|2579400_2580615_-\|tail	tail fiber protein	B6DZB7	Enterobacteria_phage	4.0e-78	94.8
WP_001233130.1\|2580679_2581279_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	1.8e-108	97.5
WP_106875441.1\|2581346_2584823_-	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	89.9
WP_158707429.1\|2585061_2585694_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	5.8e-105	93.3
WP_024236318.1\|2585639_2586383_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	1.9e-147	97.2
WP_001375577.1\|2586388_2587087_-\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	4.7e-132	98.7
WP_000847304.1\|2587086_2587416_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	2.2e-55	95.4
WP_000082320.1\|2587412_2589992_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	82.3
WP_000533431.1\|2589972_2590386_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.0e-41	82.8
WP_000479086.1\|2590412_2590844_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	4.8e-42	68.1
WP_001143013.1\|2590857_2591610_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.7e-127	93.6
WP_032284507.1\|2591617_2591986_-	hypothetical protein	A0A0K2FIF4	Enterobacteria_phage	2.4e-50	88.0
WP_000099160.1\|2591982_2593521_-\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_000612626.1\|2593569_2593917_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839179.1\|2593913_2594318_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_001254029.1\|2594395_2594572_-	hypothetical protein	E4WL22	Enterobacteria_phage	1.1e-08	56.4
WP_106875443.1\|2594561_2596154_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	1.6e-183	60.9
WP_000259002.1\|2596150_2596357_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_009442816.1\|2596340_2598269_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	2.7e-262	66.4
WP_000235451.1\|2598240_2598750_-\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.2e-12	33.3
WP_001307652.1\|2599145_2599340_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
WP_000881326.1\|2599527_2600145_-	hypothetical protein	A0A1R3Y613	Salmonella_virus	6.5e-93	85.9
WP_000092325.1\|2600294_2600732_-\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	1.7e-71	98.6
WP_000075132.1\|2600728_2601226_-	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_000411802.1\|2601225_2601432_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000499454.1\|2604042_2604201_-	DUF3927 family protein	NA	NA	NA	NA
WP_001302581.1\|2604286_2605030_-	hypothetical protein	NA	NA	NA	NA
WP_001097238.1\|2605214_2605904_-	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.5e-58	48.1
WP_032160865.1\|2605918_2606041_-	YlcG family protein	NA	NA	NA	NA
WP_000750155.1\|2606379_2607339_+	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_000994516.1\|2607550_2607739_-	protein ninH	A5VW84	Enterobacteria_phage	5.5e-27	100.0
WP_001008193.1\|2607735_2608098_-	RusA family crossover junction endodeoxyribonuclease	A5VW85	Enterobacteria_phage	2.7e-62	99.2
WP_000002261.1\|2608094_2608385_-	DUF1364 domain-containing protein	A0A192Y6R9	Salmonella_phage	2.9e-51	97.9
WP_001003989.1\|2608384_2609107_-	DNA-binding protein	K7P6K2	Enterobacteria_phage	5.4e-131	99.6
WP_001341811.1\|2609099_2609309_-	protein ninF	G9L691	Escherichia_phage	2.6e-30	97.1
WP_000924601.1\|2609268_2609670_-	hypothetical protein	Q9EYC4	Enterobacteria_phage	1.4e-72	100.0
WP_001254255.1\|2609672_2609849_-	NinE family protein	A5VW90	Enterobacteria_phage	4.6e-28	100.0
WP_000814611.1\|2609845_2610256_-	recombination protein NinB	A0A0P0ZCW6	Stx2-converting_phage	2.1e-71	99.3
WP_000344573.1\|2610227_2610584_-	hypothetical protein	K7PHN9	Enterobacterial_phage	2.1e-59	97.3
WP_000145926.1\|2610880_2611171_-	protein ren	O48423	Enterobacteria_phage	9.6e-47	100.0
WP_032278733.1\|2611167_2611848_-	Replication protein P	K7P6G2	Enterobacteria_phage	1.4e-125	99.1
WP_000438538.1\|2612824_2613124_-	hypothetical protein	A0A0P0ZBJ0	Stx2-converting_phage	4.8e-49	99.0
WP_000064150.1\|2613262_2613496_-	hypothetical protein	A0A0P0ZDD7	Stx2-converting_phage	4.0e-35	97.4
WP_000428099.1\|2613609_2614314_+	helix-turn-helix transcriptional regulator	A0A0P0ZE37	Stx2-converting_phage	4.3e-133	99.6
WP_000193240.1\|2614582_2614945_+	hypothetical protein	A0A1P8DTD0	Proteus_phage	6.2e-19	51.4
WP_000088201.1\|2615551_2615824_+	hypothetical protein	A0A0N7C217	Escherichia_phage	7.4e-41	98.9
WP_000073663.1\|2615847_2616387_-	superinfection exclusion protein B	A0A192Y7Z0	Salmonella_phage	8.1e-39	44.9
WP_001341800.1\|2616750_2617611_+	hypothetical protein	K7P7J7	Enterobacteria_phage	2.4e-37	99.3
WP_000638547.1\|2617635_2617767_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	A5VWA4	Enterobacteria_phage	1.4e-16	100.0
WP_001243354.1\|2617751_2617904_+	host cell division inhibitory peptide Kil	A5VWA5	Enterobacteria_phage	1.5e-19	98.0
WP_000031370.1\|2618160_2618766_+	ERF family protein	Q9MCQ9	Enterobacteria_phage	4.1e-108	100.0
WP_000951334.1\|2618765_2619149_+	hypothetical protein	K7P6P8	Enterobacteria_phage	2.5e-66	98.4
WP_001111278.1\|2619172_2619466_+	DUF2856 family protein	G8C7L1	Escherichia_phage	2.5e-50	99.0
WP_001214436.1\|2619476_2619641_+	DUF2737 family protein	K7P7R0	Enterobacteria_phage	4.2e-23	98.1
WP_000812206.1\|2619637_2620195_+	hypothetical protein	E7C9P6	Salmonella_phage	3.2e-62	64.3
WP_000034231.1\|2620191_2620749_+	ead/Ea22-like family protein	A5VWB3	Enterobacteria_phage	4.6e-45	83.6
WP_000104414.1\|2620750_2621368_+	hypothetical protein	Q716F4	Shigella_phage	5.6e-36	64.2
WP_012817743.1\|2621364_2621667_+	restriction alleviation protein, Lar family	Q716F5	Shigella_phage	9.4e-53	97.0
WP_032278566.1\|2621659_2621944_+	ASCH domain-containing protein	A0A2D1GLL3	Escherichia_phage	3.5e-49	98.9
WP_000545733.1\|2622016_2622184_+	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	1.3e-27	100.0
WP_001281774.1\|2622212_2622557_+	hypothetical protein	K7PJY7	Enterobacterial_phage	4.5e-59	98.2
WP_001303849.1\|2622663_2622882_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000533654.1\|2622859_2623930_+\|integrase	tyrosine-type recombinase/integrase	K7P6P6	Enterobacteria_phage	5.6e-201	99.4
2625364:2625398	attR	NA	NA	NA	NA

DBSCAN-SWA_14

2852468 : 2902172

Enterobacteria_phage(58.93%)

protease,integrase,terminase,lysis,transposase,tail,capsid,head,portal

attL 2852000:2852046|attR 2902186:2902232

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2852000:2852046	attL	NA	NA	NA	NA
WP_001201825.1\|2852468_2853422_+\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001226384.1\|2853608_2855093_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000937502.1\|2855276_2855582_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.8e-12	76.5
WP_000239881.1\|2855638_2856307_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000279150.1\|2856945_2859906_-	membrane protein	A0A2D1UII2	Escherichia_phage	3.0e-58	98.3
WP_001230523.1\|2859970_2860570_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	1.8e-108	97.5
WP_000515439.1\|2860640_2864054_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	97.2
WP_000090884.1\|2864114_2864747_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	8.5e-96	99.0
WP_001152557.1\|2865432_2866131_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	3.4e-130	96.6
WP_000847347.1\|2866130_2866460_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	3.6e-58	99.1
WP_000840236.1\|2866456_2869018_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	92.1
WP_000459457.1\|2869010_2869445_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479169.1\|2869426_2869849_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.1e-70	96.4
WP_001342267.1\|2869864_2870605_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	1.0e-129	98.0
WP_000683110.1\|2870612_2871008_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	2.9e-70	99.2
WP_000985132.1\|2871004_2871583_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
WP_000752961.1\|2871573_2871948_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	8.0e-62	99.1
WP_000158868.1\|2871959_2872355_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	5.7e-58	95.5
WP_000063244.1\|2872396_2873422_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.8e-188	97.7
WP_001345004.1\|2873477_2873810_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.0e-55	99.1
WP_000088640.1\|2873819_2874698_-	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	1.7e-147	99.0
WP_001339397.1\|2874738_2875416_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|2875415_2875763_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381395.1\|2875782_2877354_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_001444138.1\|2877826_2879428_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	8.5e-310	99.1
WP_000198149.1\|2879424_2879631_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_052922144.1\|2879627_2881553_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.5
WP_000453558.1\|2881527_2882073_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	4.0e-94	98.3
WP_001427981.1\|2882461_2882656_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.4e-27	95.3
WP_106875444.1\|2882773_2883986_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_157825797.1\|2883952_2884120_+	hypothetical protein	NA	NA	NA	NA
WP_000738423.1\|2884327_2884621_+	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
WP_001228695.1\|2884711_2884894_-\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_001135274.1\|2885110_2885608_-	lysozyme	M1FJA0	Enterobacteria_phage	3.2e-90	97.0
WP_000839596.1\|2885607_2885823_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000737278.1\|2886411_2887494_+	porin OmpD	Q1MVN1	Enterobacteria_phage	7.8e-166	80.6
WP_001204791.1\|2887682_2888066_-	antitermination protein QuuD	A0A088CD47	Shigella_phage	4.4e-55	83.3
WP_000971074.1\|2888151_2888292_-	YlcG family protein	K7PHH3	Enterobacteria_phage	6.5e-09	69.8
WP_001099712.1\|2888288_2888651_-	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	4.3e-60	96.5
WP_000774477.1\|2888647_2888938_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	6.0e-49	96.9
WP_000224914.1\|2888930_2889101_-	hypothetical protein	K7P7K0	Enterobacteria_phage	2.4e-13	69.8
WP_001053023.1\|2889100_2889556_-	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	3.1e-60	67.5
WP_072097617.1\|2889552_2889654_-	hypothetical protein	NA	NA	NA	NA
WP_000520500.1\|2889777_2890179_-	hypothetical protein	NA	NA	NA	NA
WP_001038620.1\|2890157_2890574_-	HEPN domain-containing protein	NA	NA	NA	NA
WP_001415151.1\|2890873_2891482_-	hypothetical protein	Q9T1Q5	Acyrthosiphon_pisum_secondary_endosymbiont_phage	1.5e-33	67.3
WP_000152742.1\|2892234_2892582_+	hypothetical protein	NA	NA	NA	NA
WP_000788789.1\|2892786_2893488_-	Replication protein P	M1FJ72	Enterobacteria_phage	3.8e-129	98.7
WP_001342088.1\|2893484_2894414_-	replication protein	M1FN81	Enterobacteria_phage	4.4e-109	67.0
WP_001182773.1\|2894500_2895040_-	hypothetical protein	M9NZI6	Enterobacteria_phage	2.6e-61	66.1
WP_001067458.1\|2895109_2895340_-	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
WP_000858975.1\|2895444_2896134_+	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.8e-92	75.0
WP_000066829.1\|2896215_2896479_+	hypothetical protein	A0A2H4FNC7	Salmonella_phage	4.2e-41	95.4
WP_001444023.1\|2896614_2896935_+	hypothetical protein	NA	NA	NA	NA
WP_000206913.1\|2897401_2897692_+	hypothetical protein	K7P6H3	Enterobacteria_phage	2.5e-26	82.4
WP_000995439.1\|2897767_2898064_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_001427106.1\|2898069_2898855_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	1.8e-148	99.6
WP_000611716.1\|2898851_2899532_+	YqaJ viral recombinase family protein	B6DZ61	Enterobacteria_phage	3.0e-131	98.2
WP_000149544.1\|2899528_2899711_+	DUF1317 domain-containing protein	A0A1U8QQC1	Enterobacteria_phage	6.9e-27	96.7
WP_000548537.1\|2899683_2899875_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_001443983.1\|2899885_2900167_+	hypothetical protein	A0A0P0ZE02	Stx2-converting_phage	7.2e-47	98.9
WP_000763390.1\|2900265_2900484_+	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	4.9e-35	98.6
WP_000488407.1\|2900531_2900810_+	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
WP_000446905.1\|2900781_2901153_+	helix-turn-helix domain-containing protein	M1FJ59	Enterobacteria_phage	2.1e-46	81.0
WP_000051902.1\|2901008_2902172_+\|integrase	site-specific integrase	A0A088CD23	Shigella_phage	3.0e-200	86.6
2902186:2902232	attR	NA	NA	NA	NA

DBSCAN-SWA_15

3642057 : 3683292

Stx2-converting_phage(57.14%)

transposase,integrase

attL 3669461:3669475|attR 3683462:3683476

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000099160.1\|3642057_3643596_-\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_000612626.1\|3643644_3643992_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839179.1\|3643988_3644393_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_077221339.1\|3644842_3645121_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_001344112.1\|3645754_3645931_+	hemolysin activation protein	NA	NA	NA	NA
WP_001339397.1\|3645998_3646676_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|3646675_3647023_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381395.1\|3647042_3648614_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000221529.1\|3649353_3649923_+	inovirus Gp2 family protein	NA	NA	NA	NA
WP_000271003.1\|3650088_3650490_+	hypothetical protein	NA	NA	NA	NA
WP_001221615.1\|3650477_3650912_+	hypothetical protein	NA	NA	NA	NA
WP_133395011.1\|3651332_3651647_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	4.5e-50	99.0
WP_000612591.1\|3651643_3651991_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998019.1\|3652040_3653426_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.4e-259	89.3
WP_000823243.1\|3653664_3655023_-	esterase-like activity of phytase family protein	NA	NA	NA	NA
WP_000555341.1\|3655755_3656013_-	hypothetical protein	NA	NA	NA	NA
WP_001283626.1\|3657762_3658284_+	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_001068905.1\|3658280_3659234_+	fec operon regulator FecR	NA	NA	NA	NA
WP_000188267.1\|3659320_3661645_+	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
WP_000879164.1\|3661689_3662592_+	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_000125190.1\|3662588_3663587_+	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_000684856.1\|3663583_3664540_+	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
WP_000175457.1\|3664540_3665308_+	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
WP_000177060.1\|3665865_3666123_-	hypothetical protein	NA	NA	NA	NA
WP_000227281.1\|3667476_3668049_+	hypothetical protein	Q858R9	Enterobacteria_phage	2.2e-71	69.0
WP_000594911.1\|3668097_3668922_-	hypothetical protein	L7TR00	Rhizobium_phage	3.0e-16	35.5
3669461:3669475	attL	NA	NA	NA	NA
WP_000016235.1\|3669827_3672161_-	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	72.8
WP_000842358.1\|3672175_3672499_-	DUF5375 family protein	NA	NA	NA	NA
WP_001014979.1\|3672495_3672720_-	hypothetical protein	NA	NA	NA	NA
WP_000761643.1\|3672719_3673268_-	ash family protein	Q7M2A7	Enterobacteria_phage	5.9e-29	64.8
WP_001084853.1\|3673264_3673525_-	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.6e-24	67.5
WP_000214377.1\|3674429_3675182_+	hypothetical protein	NA	NA	NA	NA
WP_000991130.1\|3675178_3675733_+	hypothetical protein	NA	NA	NA	NA
WP_001185332.1\|3675734_3676007_+	ogr/Delta-like zinc finger family protein	A0A2I8TV89	Erwinia_phage	8.3e-08	46.9
WP_000381395.1\|3676316_3677888_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|3677907_3678255_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|3678254_3678932_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000091133.1\|3679221_3680808_+	hypothetical protein	NA	NA	NA	NA
WP_032276966.1\|3680946_3681786_+	hypothetical protein	NA	NA	NA	NA
WP_000772685.1\|3682029_3683292_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	2.8e-74	40.3
3683462:3683476	attR	NA	NA	NA	NA

DBSCAN-SWA_16

3704566 : 3765138

Stx2-converting_phage(25.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000399685.1\|3704566_3705547_+\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
WP_000471889.1\|3705774_3708471_-	magnesium-translocating P-type ATPase	M1HLC0	Paramecium_bursaria_Chlorella_virus	9.0e-46	27.4
WP_001387276.1\|3708611_3708665_-	mgtA regulatory leader peptide MgtL	NA	NA	NA	NA
WP_001181312.1\|3708849_3709797_+	HTH-type transcriptional regulator TreR	C6ZCU4	Enterobacteria_phage	7.9e-13	21.8
WP_001297258.1\|3709915_3711337_+	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_001341327.1\|3711386_3713042_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_000187778.1\|3713435_3715574_+	anaerobic ribonucleoside-triphosphate reductase	A0A2I7QNQ7	Vibrio_phage	1.5e-266	64.5
WP_001106238.1\|3715732_3716197_+	anaerobic ribonucleoside-triphosphate reductase-activating protein	K4F9T1	Cronobacter_phage	1.1e-52	57.1
WP_000839179.1\|3716632_3717037_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_000612626.1\|3717033_3717381_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000099160.1\|3717429_3718968_+\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_001162171.1\|3719272_3720625_-\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_000166267.1\|3720718_3721270_+	ribosome-associated protein	NA	NA	NA	NA
WP_001219792.1\|3721425_3722799_-	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	NA	NA	NA	NA
WP_000853753.1\|3722974_3723973_+	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	5.7e-70	42.7
WP_000596015.1\|3724005_3725001_-	sugar ABC transporter permease YjfF	NA	NA	NA	NA
WP_001296689.1\|3724987_3726010_-	ABC transporter permease	NA	NA	NA	NA
WP_000205813.1\|3726023_3727526_-	sugar ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.4e-11	30.3
WP_000265933.1\|3727665_3728622_-	galactofuranose ABC transporter substrate-binding protein YtfQ	NA	NA	NA	NA
WP_000055075.1\|3728931_3729462_+	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	1.2e-55	63.3
WP_000239579.1\|3729541_3729892_-	endoribonuclease toxin ChpB	NA	NA	NA	NA
WP_001223208.1\|3729885_3730137_-	type II toxin-antitoxin system ChpS family antitoxin	NA	NA	NA	NA
WP_001219160.1\|3730348_3730690_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_000060926.1\|3730692_3734472_-	autotransporter assembly complex protein TamB	NA	NA	NA	NA
WP_001269327.1\|3734468_3736202_-	autotransporter assembly complex protein TamA	NA	NA	NA	NA
WP_001295196.1\|3736407_3737046_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_000935042.1\|3737368_3738712_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_000689228.1\|3738773_3738980_-	DUF1107 domain-containing protein	NA	NA	NA	NA
WP_000175289.1\|3739304_3739862_+	YtfJ family protein	NA	NA	NA	NA
WP_000886909.1\|3739851_3740592_-	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_000589460.1\|3740781_3742725_+	2',3'-cyclic-nucleotide 2'-phosphodiesterase	NA	NA	NA	NA
WP_000084622.1\|3742853_3743234_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000560553.1\|3743322_3744183_+	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_001296686.1\|3744290_3745256_+	DMT family transporter	NA	NA	NA	NA
WP_000331456.1\|3745363_3746026_+	iron-sulfur cluster repair protein YtfE	NA	NA	NA	NA
WP_106875453.1\|3746272_3747340_-	hypothetical protein	NA	NA	NA	NA
WP_001062220.1\|3747438_3747873_-	hypothetical protein	NA	NA	NA	NA
WP_000228344.1\|3748139_3749543_-	D-serine/D-alanine/glycine transporter	NA	NA	NA	NA
WP_000211225.1\|3749851_3750472_-	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_001119478.1\|3750690_3751329_+	cell division protein YtfB	NA	NA	NA	NA
WP_000440544.1\|3751463_3752672_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	6.4e-209	93.8
WP_072097616.1\|3752679_3753294_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	1.8e-42	59.1
WP_001427815.1\|3753733_3754528_+	DUF2686 family protein	NA	NA	NA	NA
WP_001196062.1\|3754598_3755048_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_000135199.1\|3755089_3755317_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_001296681.1\|3755321_3755636_-	primosomal replication protein N	NA	NA	NA	NA
WP_001216676.1\|3755642_3756038_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_000492914.1\|3756364_3756640_+	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_001170812.1\|3756768_3757455_-	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
WP_000949511.1\|3757454_3758309_-	L-ribulose-5-phosphate 3-epimerase	NA	NA	NA	NA
WP_000056760.1\|3758318_3758969_-	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	NA	NA	NA	NA
WP_000776505.1\|3758982_3759447_-	PTS ascorbate transporter subunit IIA	NA	NA	NA	NA
WP_000218360.1\|3759456_3759762_-	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
WP_001295191.1\|3761529_3762594_+	L-ascorbate 6-phosphate lactonase	NA	NA	NA	NA
WP_000133631.1\|3762701_3763457_+	HTH-type transcriptional regulator UlaR	NA	NA	NA	NA
WP_000569731.1\|3763453_3764203_-	esterase	NA	NA	NA	NA
WP_000254642.1\|3764384_3764714_+	biofilm peroxide resistance protein BsmA	NA	NA	NA	NA
WP_000811566.1\|3764862_3765138_+\|protease	protease activator YjfN	NA	NA	NA	NA

DBSCAN-SWA_17

3776850 : 3824770

Vibrio_phage(20.0%)

protease,transposase,tRNA,integrase

attL 3790362:3790376|attR 3822423:3822437

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001232412.1\|3776850_3777855_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_000312488.1\|3777857_3779117_-\|protease	FtsH protease activity modulator HflK	A0A1L2CVV0	Pectobacterium_phage	3.6e-05	25.5
WP_000460361.1\|3779202_3780483_-	GTPase HflX	NA	NA	NA	NA
WP_001051883.1\|3780559_3780868_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_001280349.1\|3780953_3781904_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_001122520.1\|3781896_3783744_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	5.8e-60	41.3
WP_000990262.1\|3783753_3785088_-	N-acetylmuramoyl-L-alanine amidase AmiB	A0A067ZJB6	Vibrio_phage	8.8e-18	31.0
WP_000981977.1\|3785106_3785568_-\|tRNA	tRNA (N6-adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase TsaE	NA	NA	NA	NA
WP_001307537.1\|3785539_3787087_-	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_001294203.1\|3787085_3788225_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_100699686.1\|3788207_3788261_-	hypothetical protein	NA	NA	NA	NA
WP_001295188.1\|3789124_3789670_-	oligoribonuclease	Q8B5Y0	Diachasmimorpha_longicaudata_entomopoxvirus	2.2e-28	40.4
WP_000041970.1\|3789764_3790817_+	small ribosomal subunit biogenesis GTPase RsgA	NA	NA	NA	NA
3790362:3790376	attL	NA	NA	NA	NA
WP_000934920.1\|3790913_3791882_+	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_001236850.1\|3791903_3795227_+	miniconductance mechanosensitive channel MscM	NA	NA	NA	NA
WP_001276180.1\|3795255_3795570_-	YjeO family protein	NA	NA	NA	NA
WP_000342867.1\|3795566_3795881_-	hypothetical protein	NA	NA	NA	NA
WP_001346081.1\|3795932_3797435_-	glutamate/gamma-aminobutyrate family transporter YjeM	NA	NA	NA	NA
WP_000004771.1\|3797653_3798631_-	elongation factor P--(R)-beta-lysine ligase	A0A2K9KZX5	Tupanvirus	6.8e-28	28.2
WP_001192991.1\|3798955_3800764_+	fumarate reductase (quinol) flavoprotein subunit	NA	NA	NA	NA
WP_063625657.1\|3800756_3801491_+	succinate dehydrogenase/fumarate reductase iron-sulfur subunit	NA	NA	NA	NA
WP_000208757.1\|3801501_3801897_+	fumarate reductase subunit FrdC	NA	NA	NA	NA
WP_001299198.1\|3801907_3802267_+	fumarate reductase subunit FrdD	NA	NA	NA	NA
WP_001299193.1\|3802329_3803463_+	BlaEC family class C beta-lactamase	NA	NA	NA	NA
WP_001238378.1\|3803551_3804085_+	lipocalin family protein	A0A1W6JNX6	Morganella_phage	2.7e-47	55.0
WP_000118482.1\|3804081_3804399_-	quaternary ammonium compound efflux SMR transporter SugE	NA	NA	NA	NA
WP_000239596.1\|3804580_3804727_-	lipoprotein toxin entericidin B	NA	NA	NA	NA
WP_000977757.1\|3804837_3804963_-	lipoprotein antitoxin entericidin A	NA	NA	NA	NA
WP_000257278.1\|3805014_3805581_-	elongation factor P	NA	NA	NA	NA
WP_000940530.1\|3805622_3806651_+	EF-P beta-lysylation protein EpmB	NA	NA	NA	NA
WP_001008073.1\|3807040_3807910_+	hypothetical protein	NA	NA	NA	NA
WP_000399648.1\|3808158_3809139_-\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
WP_000558209.1\|3809391_3809745_-	DUF4156 domain-containing protein	NA	NA	NA	NA
WP_000729117.1\|3809882_3811529_-	chaperonin GroEL	A0A2I7SAK5	Vibrio_phage	5.3e-190	68.9
WP_001026276.1\|3811572_3811866_-	co-chaperone GroES	K4F9I2	Cronobacter_phage	9.2e-13	45.4
WP_000015837.1\|3812141_3813398_+	L-methionine/branched-chain amino acid transporter	NA	NA	NA	NA
WP_001267448.1\|3813413_3813890_-	membrane protein FxsA	NA	NA	NA	NA
WP_001427817.1\|3814226_3815663_+	aspartate ammonia-lyase	NA	NA	NA	NA
WP_000961959.1\|3815780_3817082_+	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_000883338.1\|3817197_3817536_+	divalent cation tolerance protein CutA	NA	NA	NA	NA
WP_106875454.1\|3817511_3819209_+	protein-disulfide reductase DsbD	NA	NA	NA	NA
WP_001188520.1\|3819245_3819821_+	transcriptional regulator	NA	NA	NA	NA
WP_001218841.1\|3820200_3821466_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	2.7e-77	38.3
WP_000704132.1\|3821582_3823154_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	5.8e-295	98.6
3822423:3822437	attR	NA	NA	NA	NA
WP_001375513.1\|3823150_3824770_-\|transposase	ISL3-like element ISEc38 family transposase	NA	NA	NA	NA

DBSCAN-SWA_18

4239378 : 4252710

Enterobacteria_phage(66.67%)

transposase,integrase

attL 4239196:4239218|attR 4253195:4253217

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4239196:4239218	attL	NA	NA	NA	NA
WP_001218979.1\|4239378_4240548_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.7e-198	88.1
WP_000119815.1\|4240567_4242427_+	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	1.8e-13	22.4
WP_000186475.1\|4242423_4242849_+	hypothetical protein	NA	NA	NA	NA
WP_000446132.1\|4243176_4243749_-	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	2.2e-95	97.3
WP_000638629.1\|4243822_4244323_-	transactivation protein	NA	NA	NA	NA
WP_001283024.1\|4244319_4245054_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	5.7e-128	98.0
WP_001149160.1\|4245605_4245872_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_000980227.1\|4245868_4246468_+	ash family protein	Q7M2A7	Enterobacteria_phage	6.0e-51	81.8
WP_001244665.1\|4246460_4246748_+	hypothetical protein	Q7M2A0	Enterobacteria_phage	8.6e-48	97.9
WP_000459320.1\|4246740_4247196_+	hypothetical protein	Q7M298	Enterobacteria_phage	6.1e-64	98.2
WP_000381395.1\|4247270_4248842_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|4248861_4249209_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|4249208_4249886_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000856729.1\|4250041_4250362_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_000783645.1\|4250376_4252710_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	98.6
4253195:4253217	attR	NA	NA	NA	NA

DBSCAN-SWA_19

4503981 : 4605318

107

Escherichia_phage(54.17%)

holin,protease,tRNA,integrase,terminase,lysis,transposase,capsid,tail,portal,head,plate

attL 4508542:4508601|attR 4604159:4604238

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000560983.1\|4503981_4504419_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_001297068.1\|4504463_4505405_+	fatty acid biosynthesis protein FabY	NA	NA	NA	NA
WP_001162704.1\|4505468_4506377_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000897305.1\|4506605_4506917_+	hypothetical protein	NA	NA	NA	NA
WP_000356397.1\|4506917_4507208_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001295676.1\|4507812_4508031_+	CopG family transcriptional regulator	NA	NA	NA	NA
WP_001086390.1\|4508249_4508492_+	hypothetical protein	NA	NA	NA	NA
4508542:4508601	attL	NA	NA	NA	NA
WP_000027708.1\|4508822_4509752_-	formate dehydrogenase accessory protein FdhE	NA	NA	NA	NA
WP_000829008.1\|4509748_4510384_-	formate dehydrogenase cytochrome b556 subunit	NA	NA	NA	NA
WP_000331377.1\|4510380_4511283_-	formate dehydrogenase O subunit beta	NA	NA	NA	NA
WP_011310337.1\|4511295_4514346_-	formate dehydrogenase-N subunit alpha	A0A077SK27	Escherichia_phage	1.1e-07	23.8
WP_000753589.1\|4514539_4515373_+	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_001298963.1\|4515525_4516566_+	YiiG family protein	NA	NA	NA	NA
WP_000931345.1\|4516615_4518364_-	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_001019489.1\|4518363_4519434_-	aminopeptidase	NA	NA	NA	NA
WP_000446023.1\|4519423_4520875_-	PTS fructose-like transporter subunit IIBC	NA	NA	NA	NA
WP_000729592.1\|4520885_4521332_-	PTS fructose transporter subunit IIA	NA	NA	NA	NA
WP_000619503.1\|4521644_4521959_-	L-rhamnose mutarotase	NA	NA	NA	NA
WP_000009269.1\|4521955_4523104_-	lactaldehyde reductase	NA	NA	NA	NA
WP_001179751.1\|4523175_4524000_-	rhamnulose-1-phosphate aldolase	NA	NA	NA	NA
WP_032277158.1\|4524082_4525342_-	L-rhamnose isomerase	NA	NA	NA	NA
WP_000144123.1\|4525338_4526808_-	rhamnulokinase	NA	NA	NA	NA
WP_001341797.1\|4527095_4527572_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_001341961.1\|4527546_4527933_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001369519.1\|4527916_4528855_+	HTH-type transcriptional activator RhaR	NA	NA	NA	NA
WP_000063496.1\|4528851_4529886_-	L-rhamnose/proton symporter RhaT	NA	NA	NA	NA
WP_001297064.1\|4530170_4530791_+	superoxide dismutase [Mn]	Q56AR7	Bacillus_thuringiensis_phage	4.9e-64	59.8
WP_001387204.1\|4531088_4532033_+	2-keto-3-deoxygluconate transporter	NA	NA	NA	NA
WP_001270270.1\|4532181_4532856_+	6-N-hydroxylaminopurine resistance protein	NA	NA	NA	NA
WP_000580417.1\|4532997_4534371_-	envelope stress sensor histidine kinase CpxA	W8CYF6	Bacillus_phage	3.8e-16	25.9
WP_001033722.1\|4534367_4535066_-	envelope stress response regulator transcription factor CpxR	Q6XM27	Feldmannia_irregularis_virus	5.3e-06	30.3
WP_001223800.1\|4535215_4535716_+	cell-envelope stress modulator CpxP	NA	NA	NA	NA
WP_000985246.1\|4535902_4536883_-\|integrase	tyrosine-type recombinase/integrase	S4TP66	Salmonella_phage	4.7e-186	100.0
WP_000777029.1\|4536952_4537246_-	helix-turn-helix domain-containing protein	Q1JS37	Enterobacteria_phage	2.7e-49	100.0
WP_001308179.1\|4537382_4537655_+	hypothetical protein	Q1JS36	Enterobacteria_phage	1.4e-47	100.0
WP_000217670.1\|4537824_4538325_+	hypothetical protein	M1SV55	Escherichia_phage	2.6e-92	100.0
WP_000557703.1\|4538388_4538613_+	DUF2732 family protein	S4TP68	Salmonella_phage	4.7e-33	100.0
WP_001277952.1\|4538612_4538915_+	DUF5405 family protein	A0A0F7LDT6	Escherichia_phage	2.5e-45	96.0
WP_001113270.1\|4538914_4539139_+	TraR/DksA family transcriptional regulator	A0A0F7LDI3	Escherichia_phage	3.8e-35	98.6
WP_000027659.1\|4539135_4539411_+	DUF5405 family protein	A0A0F7LCM4	Escherichia_phage	2.3e-45	100.0
WP_032277160.1\|4539400_4541677_+	replication endonuclease	Q858T4	Yersinia_virus	0.0e+00	97.9
WP_106875458.1\|4541877_4542822_+	DNA cytosine methyltransferase	Q7Y4B5	Escherichia_virus	2.1e-143	76.0
WP_000142509.1\|4542829_4543819_-	hypothetical protein	NA	NA	NA	NA
WP_000559725.1\|4543808_4544930_-	ParB N-terminal domain-containing protein	Q858T2	Yersinia_virus	1.2e-97	62.2
WP_000038159.1\|4545344_4546379_-\|portal	phage portal protein	M1SV64	Escherichia_phage	2.1e-200	99.4
WP_032277161.1\|4546378_4548151_-\|terminase	terminase ATPase subunit family protein	A0A0F7LCK3	Escherichia_phage	0.0e+00	99.7
WP_016237183.1\|4548324_4549179_+\|capsid	GPO family capsid scaffolding protein	Q94MK3	Enterobacteria_phage	5.6e-135	99.6
WP_016242816.1\|4549237_4550311_+\|capsid	phage major capsid protein, P2 family	Q778Y7	Enterobacteria_phage	4.3e-201	99.2
WP_032277162.1\|4550314_4551058_+\|terminase	terminase endonuclease subunit	A0A0F7LBP7	Escherichia_phage	1.8e-121	96.8
WP_000988633.1\|4551157_4551667_+\|head	head completion/stabilization protein	U5N0S3	Enterobacteria_phage	1.1e-90	100.0
WP_032277163.1\|4551666_4551870_+\|tail	tail protein X	M1RZ22	Escherichia_phage	9.8e-30	97.0
WP_000123124.1\|4551873_4552155_+\|holin	holin	A0A0F7LDF8	Escherichia_phage	3.7e-43	100.0
WP_001144101.1\|4552154_4552652_+	glycoside hydrolase family 104 protein	A0A0F7LBS0	Escherichia_phage	3.1e-93	100.0
WP_032277164.1\|4552666_4553092_+	hypothetical protein	Q858W1	Yersinia_virus	4.2e-59	88.7
WP_021548485.1\|4553079_4553505_+\|lysis	LysB family phage lysis regulatory protein	Q858W0	Yersinia_virus	1.2e-64	95.0
WP_001440152.1\|4553476_4553650_+	hypothetical protein	Q7Y4E1	Escherichia_virus	2.3e-24	96.5
WP_000917189.1\|4553612_4554080_+\|tail	phage tail protein	U5N0S7	Enterobacteria_phage	2.5e-81	98.1
WP_028985812.1\|4554072_4554525_+	phage virion morphogenesis protein	A0A0F7LDR6	Escherichia_phage	1.4e-76	99.3
WP_032277166.1\|4554591_4555227_+\|plate	phage baseplate assembly protein V	A0A0F7LBP2	Escherichia_phage	4.2e-111	98.1
WP_032277167.1\|4555223_4555571_+\|plate	baseplate assembly protein	A0A0F7L9X3	Escherichia_phage	8.5e-58	99.1
WP_001121474.1\|4555575_4556484_+\|plate	baseplate assembly protein	A0A0F7LCJ3	Escherichia_phage	1.2e-162	100.0
WP_001285337.1\|4556476_4557088_+\|tail	phage tail protein I	A0A0F7LA36	Escherichia_phage	4.9e-117	99.5
WP_032277171.1\|4558419_4559022_+\|tail	tail fiber assembly protein	K7P870	Enterobacteria_phage	2.7e-91	84.8
WP_000376436.1\|4558993_4559413_-\|tail	tail assembly chaperone	A0A0F7LDZ0	Escherichia_phage	1.7e-36	55.8
WP_077628649.1\|4559416_4559818_-\|tail	phage tail protein	F1BUP1	Erwinia_phage	4.5e-10	38.4
WP_000905108.1\|4559845_4560439_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	8.7e-103	96.4
WP_001286716.1\|4560498_4561689_+\|tail	phage tail sheath protein	A0A0F7LBW9	Escherichia_phage	1.6e-225	100.0
WP_001251408.1\|4561701_4562220_+\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	1.4e-93	100.0
WP_001031312.1\|4562276_4562552_+\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	2.2e-40	98.9
WP_000785970.1\|4562584_4562704_+\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.0e-15	100.0
WP_032277172.1\|4562696_4565144_+\|tail	phage tail tape measure protein	M1T2S3	Escherichia_phage	0.0e+00	93.1
WP_000978890.1\|4565158_4565638_+\|tail	phage tail protein	O64315	Escherichia_phage	1.1e-84	99.4
WP_032277174.1\|4565637_4566801_+	phage late control D family protein	M1SV93	Escherichia_phage	1.4e-205	99.2
WP_000468308.1\|4566882_4567101_+	prophage transcriptional regulator OgrK	A0A0F7LDQ9	Escherichia_phage	4.7e-38	100.0
WP_001076742.1\|4567337_4568240_+	CDF family cation-efflux transporter FieF	NA	NA	NA	NA
WP_000591795.1\|4568420_4569383_+	6-phosphofructokinase	NA	NA	NA	NA
WP_001045673.1\|4569701_4570691_+	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000708994.1\|4570797_4571553_+	CDP-diacylglycerol diphosphatase	NA	NA	NA	NA
WP_001216325.1\|4571607_4572375_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_000802226.1\|4572482_4573082_-	YiiQ family protein	NA	NA	NA	NA
WP_000155257.1\|4573182_4573623_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_000655986.1\|4573834_4574134_+	DUF406 domain-containing protein	NA	NA	NA	NA
WP_000323556.1\|4574160_4574589_+	universal stress protein UspD	NA	NA	NA	NA
WP_000796320.1\|4574593_4575340_-	ferredoxin--NADP(+) reductase	NA	NA	NA	NA
WP_001250644.1\|4575436_4576447_-	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000136788.1\|4576581_4578090_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_000084268.1\|4578112_4578958_-	glycerol uptake facilitator protein GlpF	M1HWZ0	Paramecium_bursaria_Chlorella_virus	4.4e-15	28.0
WP_001296623.1\|4579382_4579628_+	septal ring assembly protein ZapB	NA	NA	NA	NA
WP_000872908.1\|4579712_4580198_-	ribonuclease E activity regulator RraA	NA	NA	NA	NA
WP_000139496.1\|4580290_4581217_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_001293341.1\|4581283_4582615_-	HslU--HslV peptidase ATPase subunit	A0A191ZC11	Erwinia_phage	1.7e-45	29.9
WP_000208242.1\|4582624_4583155_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_000068834.1\|4583247_4584207_-	cell division protein FtsN	NA	NA	NA	NA
WP_000644904.1\|4584298_4585324_-	DNA-binding transcriptional regulator CytR	NA	NA	NA	NA
WP_001341957.1\|4585479_4587678_-	primosomal protein N'	NA	NA	NA	NA
WP_000710769.1\|4587880_4588093_+	50S ribosomal protein L31	NA	NA	NA	NA
WP_106875459.1\|4588252_4592425_+	RHS repeat protein	A0A2H4JFP5	uncultured_Caudovirales_phage	1.0e-24	32.0
WP_000644414.1\|4592426_4592663_+	hypothetical protein	NA	NA	NA	NA
WP_000797347.1\|4593655_4594264_-	YiiX family permuted papain-like enzyme	NA	NA	NA	NA
WP_000852812.1\|4594447_4594765_-	met regulon transcriptional regulator MetJ	NA	NA	NA	NA
WP_001341952.1\|4595041_4596202_+	cystathionine gamma-synthase	NA	NA	NA	NA
WP_000110785.1\|4596204_4598637_+	bifunctional aspartate kinase/homoserine dehydrogenase II	NA	NA	NA	NA
WP_000007523.1\|4598985_4599876_+	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_001297636.1\|4600204_4602385_+	catalase/peroxidase HPI	NA	NA	NA	NA
WP_001341951.1\|4602478_4603384_+	cystine transporter YijE	NA	NA	NA	NA
WP_000647882.1\|4603410_4604028_-	DUF1287 domain-containing protein	NA	NA	NA	NA
WP_000399648.1\|4604337_4605318_-\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
4604159:4604238	attR	NA	NA	NA	NA

DBSCAN-SWA_20

5332782 : 5340731

Stx2-converting_phage(42.86%)

transposase,integrase

attL 5333674:5333690|attR 5342759:5342775

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001272558.1\|5332782_5333538_+	peptidoglycan DD-metalloendopeptidase family protein	I2E8W3	Clostridium_phage	1.1e-12	36.8
5333674:5333690	attL	NA	NA	NA	NA
WP_000935135.1\|5333824_5335432_+\|integrase	site-specific integrase	A0A059XK29	uncultured_phage	4.3e-11	28.0
WP_000852869.1\|5335424_5336084_+	DUF4145 domain-containing protein	M1PSB6	Streptococcus_phage	3.6e-33	33.9
WP_000082600.1\|5336992_5337721_+	Rha family transcriptional regulator	B5AX29	Iodobacteriophage	7.1e-14	41.2
WP_001339397.1\|5338115_5338793_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|5338792_5339140_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381395.1\|5339159_5340731_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
5342759:5342775	attR	NA	NA	NA	NA

DBSCAN-SWA_21

5492420 : 5499560

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001278994.1\|5492420_5493059_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
WP_000590392.1\|5493055_5494318_-	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_000847985.1\|5494314_5495223_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_001297141.1\|5495418_5496186_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_032276729.1\|5496236_5496893_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	3.6e-49	46.7
WP_001272924.1\|5496998_5499560_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6

DBSCAN-SWA_22

5572175 : 5677182

105

Stx2-converting_phage(38.24%)

holin,tRNA,integrase,terminase,capsid,tail,head

attL 5575897:5575911|attR 5587939:5587953

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000577251.1\|5572175_5573894_+	ATP-binding protein	A0A1B5FPD5	Escherichia_phage	6.5e-308	100.0
WP_000214985.1\|5573895_5575644_+	hypothetical protein	A0A1B5FPH1	Escherichia_phage	0.0e+00	100.0
WP_000448925.1\|5575715_5576132_-	hypothetical protein	A0A1B5FPM5	Escherichia_phage	1.1e-72	100.0
5575897:5575911	attL	NA	NA	NA	NA
WP_001427612.1\|5576170_5577391_-\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	3.5e-231	99.3
WP_001431537.1\|5577689_5578598_-	DUF4760 domain-containing protein	A0A1B5FPC5	Escherichia_phage	2.3e-171	100.0
WP_000516611.1\|5579080_5580256_-	DUF3596 domain-containing protein	I6PDJ1	Cronobacter_phage	4.6e-204	91.2
WP_000557643.1\|5580428_5580575_-	hypothetical protein	A0A0P0ZDP5	Stx2-converting_phage	1.7e-20	90.9
WP_000457722.1\|5580578_5580821_-	DUF4222 domain-containing protein	Q6H9Z8	Enterobacteria_phage	1.8e-30	82.5
WP_000206753.1\|5580905_5581769_-	DUF551 domain-containing protein	A0A088CE95	Shigella_phage	3.2e-69	53.6
WP_000034210.1\|5581770_5582100_-	ead/Ea22-like family protein	A0A0H4ISY5	Shigella_phage	1.1e-25	37.5
WP_000476199.1\|5582096_5582336_-	hypothetical protein	S5MQM0	Escherichia_phage	3.7e-36	96.2
WP_000158004.1\|5582328_5582532_-	hypothetical protein	A0A2R2Z313	Escherichia_phage	5.2e-31	95.5
WP_000335005.1\|5582528_5583407_-	phosphoadenosine phosphosulfate reductase family protein	A0A2R2Z314	Escherichia_phage	1.9e-170	94.9
WP_000008174.1\|5583397_5583934_-	5'-deoxynucleotidase	A5LH62	Enterobacteria_phage	2.8e-100	99.4
WP_032277355.1\|5584062_5584887_-	YfdQ family protein	Q8SBF9	Shigella_phage	8.6e-149	98.5
WP_000135680.1\|5584952_5585315_-	hypothetical protein	Q8SBF8	Shigella_phage	8.6e-61	100.0
WP_000859462.1\|5585981_5586656_-	LexA family transcriptional repressor	Q8SBF6	Shigella_phage	1.2e-132	100.0
WP_000649477.1\|5586746_5586947_+	transcriptional regulator	U5P445	Shigella_phage	7.9e-32	100.0
WP_000521508.1\|5586990_5587542_+	hypothetical protein	A0A291AWW8	Escherichia_phage	4.5e-101	100.0
WP_001087337.1\|5587538_5588375_+	hypothetical protein	Q8SBF3	Shigella_phage	8.7e-149	98.6
5587939:5587953	attR	NA	NA	NA	NA
WP_001444024.1\|5588379_5588604_+	hypothetical protein	A0A291AX25	Escherichia_phage	2.5e-34	94.6
WP_000061512.1\|5588600_5589419_+	helix-turn-helix domain-containing protein	Q8SBF1	Shigella_phage	3.0e-117	95.6
WP_001447905.1\|5589415_5589910_+	PerC family transcriptional regulator	A0A291AWV6	Escherichia_phage	1.2e-86	97.5
WP_001427609.1\|5589909_5590563_+	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	2.1e-126	98.6
WP_000210162.1\|5590559_5590886_+	LexA family transcriptional regulator	A0A291AWY9	Escherichia_phage	1.2e-53	99.1
WP_000767105.1\|5590882_5591272_+	RusA family crossover junction endodeoxyribonuclease	A5LH74	Enterobacteria_phage	2.1e-68	99.2
WP_001061413.1\|5591291_5592089_+	KilA-N domain-containing protein	A0A0P0ZCS0	Stx2-converting_phage	7.5e-150	99.2
WP_001427606.1\|5592096_5593086_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	1.6e-194	99.4
WP_001205460.1\|5593103_5593445_+	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	4.2e-57	90.3
WP_001131907.1\|5593457_5594006_-	hypothetical protein	NA	NA	NA	NA
WP_000868396.1\|5593992_5594919_-	hypothetical protein	NA	NA	NA	NA
WP_032284580.1\|5596038_5597976_+	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	0.0e+00	96.9
WP_000143462.1\|5598111_5598291_+	DUF1378 family protein	A0A0P0ZCJ7	Stx2-converting_phage	3.7e-25	100.0
WP_001290231.1\|5598331_5598604_+	DUF826 domain-containing protein	A0A0P0ZBB8	Stx2-converting_phage	2.2e-21	100.0
WP_000284522.1\|5598680_5598896_+\|holin	holin	Q6H9V8	Enterobacteria_phage	1.3e-32	97.2
WP_000731219.1\|5598900_5599245_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-55	96.5
WP_000992122.1\|5599295_5599829_+	lysozyme	A0A0N7KZF9	Stx2-converting_phage	2.8e-100	98.3
WP_047091958.1\|5600347_5600533_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.3e-17	98.3
WP_000736096.1\|5600618_5600843_+	hypothetical protein	NA	NA	NA	NA
WP_000095736.1\|5601211_5601439_-	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_001365481.1\|5601480_5601846_+	HNH endonuclease	A0A0P0ZCH0	Stx2-converting_phage	5.8e-65	98.3
WP_000958416.1\|5602135_5602699_+\|terminase	terminase small subunit	A0A0P0ZDD1	Stx2-converting_phage	4.7e-90	100.0
WP_072617034.1\|5602695_5604357_+\|terminase	terminase large subunit	A0A0P0ZEI4	Stx2-converting_phage	0.0e+00	99.8
WP_032284581.1\|5604420_5606358_+\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	99.8
WP_001063106.1\|5606402_5606624_+	hypothetical protein	B6DZA0	Enterobacteria_phage	2.2e-35	98.6
WP_000125984.1\|5609150_5609477_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
WP_001007905.1\|5609487_5609838_+\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000573391.1\|5609834_5610281_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_000133393.1\|5610277_5610622_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_001275441.1\|5610688_5611405_+\|tail	tail protein	A0A0P0ZDV1	Stx2-converting_phage	3.6e-127	99.6
WP_000710952.1\|5611419_5611794_+\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_122993730.1\|5611889_5612099_+	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	2.6e-30	92.8
WP_106875432.1\|5612149_5615392_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	94.8
WP_000807964.1\|5615384_5615726_+\|tail	phage tail protein	A0A0P0ZCS8	Stx2-converting_phage	8.7e-63	100.0
WP_001357740.1\|5615725_5616424_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	8.1e-132	98.7
WP_106875431.1\|5616434_5617178_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	4.1e-150	99.6
WP_096844540.1\|5617123_5617756_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-102	91.8
WP_106875462.1\|5617991_5621465_+	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	97.6
WP_001427270.1\|5621532_5622132_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	1.7e-109	98.5
WP_000268987.1\|5622196_5623510_+\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	4.8e-77	98.6
WP_001023420.1\|5623511_5623781_+\|tail	phage tail protein	H6WZN0	Escherichia_phage	3.8e-45	100.0
WP_115801847.1\|5623887_5623977_+	hypothetical protein	NA	NA	NA	NA
WP_001301673.1\|5623996_5626345_+	type III secretion system effector E3 ubiquitin ligase NleL	NA	NA	NA	NA
WP_001370486.1\|5626936_5630338_+	type III secretion system effector EspN	A0A0N7KZG3	Stx2-converting_phage	1.3e-219	39.3
WP_000938111.1\|5630714_5632076_-	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	4.3e-52	29.6
WP_000162574.1\|5633829_5634312_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_000600190.1\|5634443_5634920_+	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_001117838.1\|5634909_5635200_+	RnfH family protein	NA	NA	NA	NA
WP_001203437.1\|5635261_5635603_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_000880910.1\|5635751_5637413_-	DNA repair protein RecN	NA	NA	NA	NA
WP_001059169.1\|5637498_5638377_-	NAD(+) kinase	NA	NA	NA	NA
WP_001296310.1\|5638499_5639093_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_010723175.1\|5639147_5640434_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001338897.1\|5640454_5641246_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_000460032.1\|5641412_5642774_+	signal recognition particle protein	NA	NA	NA	NA
WP_000256450.1\|5643022_5643271_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_000043335.1\|5643289_5643838_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000264777.1\|5643868_5644636_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000065253.1\|5644677_5645025_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_000589828.1\|5645101_5645584_-	OmpA family protein	NA	NA	NA	NA
WP_000969036.1\|5645599_5646826_-	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_001212391.1\|5646815_5647334_-	YfiR family protein	NA	NA	NA	NA
WP_000976004.1\|5647483_5647849_-	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_001168054.1\|5648058_5649129_+	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	5.3e-90	51.2
WP_000225221.1\|5649139_5650261_+	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_000200116.1\|5650303_5651464_-	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_001386991.1\|5651562_5651610_-	hypothetical protein	NA	NA	NA	NA
WP_000178456.1\|5651713_5652055_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_000197686.1\|5652325_5653063_-	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000079094.1\|5653197_5654178_+	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000040115.1\|5654174_5654906_+	polyphenol oxidase	NA	NA	NA	NA
WP_001235102.1\|5655035_5657609_+	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000841103.1\|5663462_5664761_+	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	1.3e-45	32.2
WP_001300818.1\|5664757_5665081_-	YfiM family lipoprotein	NA	NA	NA	NA
WP_000949265.1\|5665126_5666482_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_000083007.1\|5666595_5669256_-	protein lysine acetyltransferase	NA	NA	NA	NA
WP_001341635.1\|5669287_5669986_-	DTW domain-containing protein	NA	NA	NA	NA
WP_001098726.1\|5670054_5670474_-	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_000997403.1\|5670680_5671718_+\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_001262716.1\|5671765_5672455_-	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	7.1e-56	48.8
WP_000627807.1\|5672759_5673143_+	autonomous glycyl radical cofactor GrcA	Q7Y524	Enterobacteria_phage	1.4e-32	72.0
WP_000189207.1\|5673198_5673786_-	cysteine/O-acetylserine transporter	NA	NA	NA	NA
WP_001341633.1\|5673888_5674770_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000219193.1\|5674978_5676313_-	ATP-dependent RNA helicase SrmB	E3T5E1	Cafeteria_roenbergensis_virus	2.9e-45	30.8
WP_001298974.1\|5676444_5677182_+\|tRNA	tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase TrmN	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP027583

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

6784 : 86216

Stx2-converting_phage(52.17%)

integrase,transposase,protease

attL 11893:11952|attR 69490:72194

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001034100.1\|6784_10687_-\|protease	serine protease autotransporter EspP	Q9LA58	Enterobacterial_phage	9.5e-238	40.4
WP_158707430.1\|11624_12044_-	DUF1449 family protein	NA	NA	NA	NA
11893:11952	attL	NA	NA	NA	NA
WP_001341423.1\|11974_12649_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	30.8
WP_000631725.1\|12645_12993_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.2e-44	72.9
WP_012917687.1\|12996_14565_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.0e-158	56.0
WP_106875464.1\|14843_16031_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000091308.1\|16030_16396_-	hypothetical protein	NA	NA	NA	NA
WP_000612591.1\|16632_16980_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_012917688.1\|17029_18568_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.9e-295	98.8
WP_012680945.1\|18871_19870_-	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_000550559.1\|19943_21665_-	phosphoethanolamine transferase CptA	NA	NA	NA	NA
WP_000975743.1\|21758_22865_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_001302199.1\|22864_23686_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_000839950.1\|26333_26849_+	enterohemolysin-activating lysine-acyltransferase EhxC	NA	NA	NA	NA
WP_000217745.1\|26850_29847_+	enterohemolysin EhxA	NA	NA	NA	NA
WP_000987096.1\|29896_32017_+	enterohemolysin T1SS ABC transporter permease/ATPase EhxB	W8CYL7	Bacillus_phage	1.6e-45	30.2
WP_001213545.1\|32020_33460_+	enterohemolysin T1SS ABC transporter subunit EhxD	NA	NA	NA	NA
WP_000864810.1\|33872_34226_-	colicin M immunity protein	NA	NA	NA	NA
WP_032277352.1\|34398_35181_-\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.8e-54	96.4
WP_000465041.1\|35182_35596_-	hypothetical protein	NA	NA	NA	NA
WP_001261287.1\|36155_36386_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_001044768.1\|36382_36799_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_001165114.1\|36960_37506_-	hypothetical protein	NA	NA	NA	NA
WP_000704534.1\|38263_39124_-	alpha/beta hydrolase	A2RQC8	Archaeal_BJ1_virus	1.3e-09	23.5
WP_001066949.1\|39251_39638_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001341423.1\|39691_40366_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	30.8
WP_000631725.1\|40362_40710_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.2e-44	72.9
WP_012917687.1\|40713_42282_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.0e-158	56.0
WP_000154135.1\|42941_43607_-	hypothetical protein	NA	NA	NA	NA
WP_000335839.1\|43747_44389_-	transcription termination factor NusG	NA	NA	NA	NA
WP_000907857.1\|45090_46122_+	replication initiation protein	NA	NA	NA	NA
WP_042842256.1\|47081_56582_-	toxin B	NA	NA	NA	NA
WP_001443774.1\|56696_56927_-\|transposase	transposase	NA	NA	NA	NA
WP_000422675.1\|60053_60530_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	3.0e-45	90.7
WP_000937603.1\|64500_65688_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000091308.1\|65687_66053_-	hypothetical protein	NA	NA	NA	NA
WP_012917687.1\|66876_68445_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.0e-158	56.0
WP_000631725.1\|68448_68796_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.2e-44	72.9
WP_001341423.1\|68792_69467_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	30.8
WP_001341442.1\|69520_69748_-\|transposase	transposase	B6DZU5	Stx2-converting_phage	6.2e-33	100.0
WP_000361610.1\|69910_70888_-	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	1.4e-100	59.2
WP_085953785.1\|71693_72906_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	2.5e-168	99.7
69490:72194	attR	NA	NA	NA	NA
WP_000592771.1\|73077_75288_+	catalase/peroxidase KatP	NA	NA	NA	NA
WP_001172748.1\|75331_75721_+	cytochrome b562 family protein	NA	NA	NA	NA
WP_000445934.1\|76681_77077_-	plasmid stabilization protein	NA	NA	NA	NA
WP_000921957.1\|77076_78036_-	plasmid stabilization protein	A0A222YXF2	Escherichia_phage	5.4e-62	40.9
WP_077249722.1\|78308_79211_+	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_000086167.1\|79594_80278_+	DNA methylase	A0A2I7RE86	Vibrio_phage	1.3e-28	37.4
WP_001443814.1\|80277_80496_+	hypothetical protein	NA	NA	NA	NA
WP_000274418.1\|80507_80942_+	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_001341455.1\|80986_81469_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_001276261.1\|81465_82185_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_032313270.1\|82461_82779_+	hypothetical protein	A0A0N7KZV3	Escherichia_phage	4.5e-05	55.8
WP_000117628.1\|83239_83740_+	antirestriction protein ArdA	NA	NA	NA	NA
WP_000218854.1\|84467_84902_+	hypothetical protein	NA	NA	NA	NA
WP_001247865.1\|84994_85261_+	hypothetical protein	NA	NA	NA	NA
WP_000038351.1\|85325_86216_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	4.4e-66	53.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP027582

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP027583

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection