CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP027546	Escherichia coli strain 2013C-4187 chromosome, complete genome	3 crisprs	PrimPol,cas3,c2c9_V-U4,DEDDh,DinG,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	0	8	18	0
NZ_CP027547	Escherichia coli strain 2013C-4187 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP027546_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027546_1

2710969-2711546

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder

9 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP027546_1

>merge|NZ_CP027546|1|2710969-2711546|CRT,PILER-CR,CRISPRCasFinder
GGGAGTTCTACCGCAGGGGCGGGGAATTCTAAGTGATATCCATCATCGCATCCAGTGCGCCCGGTTTATCCCCGCTGACGCGGGGAACACAAAACCAAACTTCTCCATAAATTCCATAGCCGCGGTTTATCCCCGCTGGCGCGGGGAACACGAGTCTATCAGCGACACTACCGGCAATAGCGACGGTTTATCCCCGCTGGCGCGGGGAACACGAGAGTGCTGACAGGTGTCTCGATTACCTGATCGGTTTATCCCCGCTGGCGCGGGGAACACGGTAGTACGCGCCTCCGGACGTTTTTATGTCGCGGTTTATCCCCGCTGGCGCGGGGAACACTCTTCGCGGGTAATCAATGATGATTCAGTTTCCGGTTTATCCCCGCTGGCGCGGGGAACACGAACGCAATATCACGGCGTTCTGCGGCCTCGGCGGTTTATCCCCGCTGGCGCGGGGAACACCAAAATATTACGAGCTTCGTCAGGCCATGGACCGGTTTATCCCCGCTGGCGCGGGGAACACGTCGGGCCGGGTAAGTGAACCTGTCGGTTTTCCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027546|1|1|2710969-2711546|CRT
GGGAGTTCTACCGCAGGGGCGGGGAATTC	TAAGTGATATCCATCATCGCATCCAGTGCGCC
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGTCTATCAGCGACACTACCGGCAATAGCGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGTAGTACGCGCCTCCGGACGTTTTTATGTCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTTCGCGGGTAATCAATGATGATTCAGTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAATATTACGAGCTTCGTCAGGCCATGGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027546|1|1|2711030-2711546|PILER-CR
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGTCTATCAGCGACACTACCGGCAATAGCGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGTAGTACGCGCCTCCGGACGTTTTTATGTCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTTCGCGGGTAATCAATGATGATTCAGTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAATATTACGAGCTTCGTCAGGCCATGGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027546|1|1|2711030-2711546|CRISPRCasFinder
CGGTTTATCCCCGCTGACGCGGGGAACAC	AAAACCAAACTTCTCCATAAATTCCATAGCCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGTCTATCAGCGACACTACCGGCAATAGCGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAGAGTGCTGACAGGTGTCTCGATTACCTGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GGTAGTACGCGCCTCCGGACGTTTTTATGTCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCTTCGCGGGTAATCAATGATGATTCAGTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GAACGCAATATCACGGCGTTCTGCGGCCTCGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CAAAATATTACGAGCTTCGTCAGGCCATGGAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCGGGCCGGGTAAGTGAACCTGTCGGTTTTC
CGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027546.1\|WP_000372108.1\|2708750_2709659_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP027546.1\|WP_000039843.1\|2720814_2721549_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP027546.1\|WP_001173673.1\|2706716_2707322_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP027546.1\|WP_000029341.1\|2715359_2715848_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP027546.1\|WP_000281440.1\|2712852_2713503_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP027546.1\|WP_001219242.1\|2704630_2705110_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP027546.1\|WP_000144863.1\|2711935_2712856_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP027546.1\|WP_001090394.1\|2707321_2708749_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP027546.1\|WP_000246138.1\|2705109_2705820_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP027546.1\|WP_000517476.1\|2705838_2706150_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP027546.1\|WP_001084096.1\|2715844_2717407_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP027546.1\|WP_001246104.1\|2706343_2706667_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP027546.1\|WP_000063176.1\|2711642_2711936_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP027546.1\|WP_000956458.1\|2720397_2720550_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP027546.1\|WP_000085039.1\|2713484_2714231_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP027546.1\|WP_000206431.1\|2714241_2715297_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP027546.1\|WP_001295182.1\|2702842_2703604_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP027546.1\|WP_000490429.1\|2709910_2710948_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP027546.1\|WP_001233933.1\|2717504_2720204_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP027546.1\|WP_000568946.1\|2703584_2704634_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884

Protein	Function_ID	Function_description	E-value
NZ_CP027546.1\|WP_000372108.1\|2708750_2709659_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP027546.1\|WP_000039843.1\|2720814_2721549_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP027546.1\|WP_001173673.1\|2706716_2707322_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP027546.1\|WP_000029341.1\|2715359_2715848_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	7.4429e-23
NZ_CP027546.1\|WP_000281440.1\|2712852_2713503_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.38075e-91
NZ_CP027546.1\|WP_001219242.1\|2704630_2705110_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP027546.1\|WP_000144863.1\|2711935_2712856_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	4.23259e-157
NZ_CP027546.1\|WP_001090394.1\|2707321_2708749_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP027546.1\|WP_000246138.1\|2705109_2705820_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
NZ_CP027546.1\|WP_000517476.1\|2705838_2706150_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP027546.1\|WP_001084096.1\|2715844_2717407_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP027546.1\|WP_001246104.1\|2706343_2706667_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP027546.1\|WP_000063176.1\|2711642_2711936_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP027546.1\|WP_000956458.1\|2720397_2720550_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP027546.1\|WP_000085039.1\|2713484_2714231_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.7086e-49
NZ_CP027546.1\|WP_000206431.1\|2714241_2715297_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	6.10696e-155
NZ_CP027546.1\|WP_001295182.1\|2702842_2703604_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP027546.1\|WP_000490429.1\|2709910_2710948_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP027546.1\|WP_001233933.1\|2717504_2720204_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.31706e-179
NZ_CP027546.1\|WP_000568946.1\|2703584_2704634_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0

>NZ_CP027546.1|WP_000490429.1|2709910_2710948_+|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP027546.1|WP_000372108.1|2708750_2709659_-|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP027546.1|WP_001090394.1|2707321_2708749_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGSKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP027546.1|WP_001173673.1|2706716_2707322_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP027546.1|WP_001246104.1|2706343_2706667_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP027546.1|WP_000517476.1|2705838_2706150_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP027546.1|WP_000246138.1|2705109_2705820_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP027546.1|WP_001219242.1|2704630_2705110_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP027546.1|WP_000568946.1|2703584_2704634_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLNDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP027546.1|WP_001295182.1|2702842_2703604_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>NZ_CP027546.1|WP_000063176.1|2711642_2711936_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP027546.1|WP_000144863.1|2711935_2712856_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPQPARRSVEQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRG
>NZ_CP027546.1|WP_000281440.1|2712852_2713503_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELCTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGPAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFVQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP027546.1|WP_000085039.1|2713484_2714231_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGGDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPELLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP027546.1|WP_000206431.1|2714241_2715297_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWSAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP027546.1|WP_000029341.1|2715359_2715848_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWREELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRIR
>NZ_CP027546.1|WP_001084096.1|2715844_2717407_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQTSFAPKNHGRWDDIWQDGLEAEKLREALLSLEHAFQFGADSPSFMQDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP027546.1|WP_001233933.1|2717504_2720204_-|CRISPR-associated-helicase/endonuclease-Cas3
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKYCSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG
>NZ_CP027546.1|WP_000956458.1|2720397_2720550_-|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP027546.1|WP_000039843.1|2720814_2721549_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG

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Crispr_ID: NZ_CP027546_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027546_2

2737248-2737702

Unclear

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGA	CRT
CGGTTTATCCCCGCTGGCGCGGGGA	PILER-CR

7 spacers

The CRISPR arrays of NZ_CP027546_2

>merge|NZ_CP027546|2|2737248-2737702|CRISPRCasFinder,CRT,PILER-CR
TGGTTTATCCCCGCTGGCGCGGGGAGCTCTACGTGAAGAATATTTGCAACACCCGCAAGAACGGTTTATCCCCGCTGGCGCGGGGAGCTCGGCATAGCCAGGCTGATCCGGCGACGGCCTTACGGTTTATCCCCGCTGGCGCGGGAACACAATCGTGTGTAAATTCGCGGCGGCTCCACTGGCGGTTTATCCCCGCTGGCGCGGGGAACACTGGTCGAAATATAGACAGCATGTTCCGTACCACGGTTTATCCCCGCTGGCGCGGGGAACACACACTATCCGGGCGGTATTACGCCCAAATATCCGGTTTATCCCCGCTGGCGCGGGGAACACCTGCCGGGTGAAACCACTCGCGGCAGATCTTGCGGTTTATCCCCGCTGGCGCGGGGAACACACTACTGTCGGTAGCTGGGAGGATGAGGAGATCGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027546|2|2|2737248-2737702|CRISPRCasFinder
TGGTTTATCCCCGCTGGCGCGGGGAGCTC	TACGTGAAGAATATTTGCAACACCCGCAAGAA
CGGTTTATCCCCGCTGGCGCGGGGAGCTC	GGCATAGCCAGGCTGATCCGGCGACGGCCTTA
CGGTTTATCCCCGCTGGCGCGGGAACACA	ATCGTGTGTAAATTCGCGGCGGCTCCACTGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGGTCGAAATATAGACAGCATGTTCCGTACCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACACTATCCGGGCGGTATTACGCCCAAATATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGCCGGGTGAAACCACTCGCGGCAGATCTTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACTACTGTCGGTAGCTGGGAGGATGAGGAGAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP027546|2|2|2737248-2737698|CRT
TGGTTTATCCCCGCTGGCGCGGGGA	GCTCTACGTGAAGAATATTTGCAACACCCGCAAGAA
CGGTTTATCCCCGCTGGCGCGGGGA	GCTCGGCATAGCCAGGCTGATCCGGCGACGGCCTTA
CGGTTTATCCCCGCTGGCGCGGGAA	CACAATCGTGTGTAAATTCGCGGCGGCTCCACTGG
CGGTTTATCCCCGCTGGCGCGGGGA	ACACTGGTCGAAATATAGACAGCATGTTCCGTACCA
CGGTTTATCCCCGCTGGCGCGGGGA	ACACACACTATCCGGGCGGTATTACGCCCAAATATC
CGGTTTATCCCCGCTGGCGCGGGGA	ACACCTGCCGGGTGAAACCACTCGCGGCAGATCTTG
CGGTTTATCCCCGCTGGCGCGGGGA	ACACACTACTGTCGGTAGCTGGGAGGATGAGGAGAT
CGGTTTATCCCCGCTGGCGCGGGGA

>NZ_CP027546|2|2|2737249-2737698|PILER-CR
GGTTTATCCCCGCTGGCGCGGGGAG	CTCTACGTGAAGAATATTTGCAACACCCGCAAGAAC
GGTTTATCCCCGCTGGCGCGGGGAG	CTCGGCATAGCCAGGCTGATCCGGCGACGGCCTTAC
GGTTTATCCCCGCTGGCGCGGGAAC	ACAATCGTGTGTAAATTCGCGGCGGCTCCACTGGC
GGTTTATCCCCGCTGGCGCGGGGAA	CACTGGTCGAAATATAGACAGCATGTTCCGTACCAC
GGTTTATCCCCGCTGGCGCGGGGAA	CACACACTATCCGGGCGGTATTACGCCCAAATATCC
GGTTTATCCCCGCTGGCGCGGGGAA	CACCTGCCGGGTGAAACCACTCGCGGCAGATCTTGC
GGTTTATCCCCGCTGGCGCGGGGAA	CACACTACTGTCGGTAGCTGGGAGGATGAGGAGATC
GGTTTATCCCCGCTGGCGCGGGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027546.1\|WP_001152074.1\|2732723_2733404_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP027546.1\|WP_000210878.1\|2741323_2742961_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP027546.1\|WP_001130266.1\|2727431_2728007_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP027546.1\|WP_000046800.1\|2746993_2748295_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|237291
NZ_CP027546.1\|WP_000254745.1\|2744050_2744386_-\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP027546.1\|WP_000036723.1\|2739937_2741236_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP027546.1\|WP_001288227.1\|2738851_2738992_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027546.1\|WP_001341835.1\|2729011_2729791_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP027546.1\|WP_001164569.1\|2733826_2735104_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP027546.1\|WP_001268451.1\|2739005_2739878_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP027546.1\|WP_001098105.1\|2729768_2731106_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP027546.1\|WP_000021313.1\|2733413_2733509_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|180761
NZ_CP027546.1\|WP_001071648.1\|2743188_2743980_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP027546.1\|WP_000581937.1\|2744385_2744634_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP027546.1\|WP_000039758.1\|2735130_2736609_+\|FGGY-family-carbohydrate-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP027546.1\|WP_000109366.1\|2727154_2727415_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289
NZ_CP027546.1\|WP_000226815.1\|2744711_2746946_-\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP027546.1\|WP_001341834.1\|2728154_2729015_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|224936
NZ_CP027546.1\|WP_000059323.1\|2731199_2732654_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP027546.1\|WP_001199970.1\|2738041_2738713_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126

Protein	Function_ID	Function_description	E-value
NZ_CP027546.1\|WP_001152074.1\|2732723_2733404_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.49633e-125
NZ_CP027546.1\|WP_000210878.1\|2741323_2742961_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP027546.1\|WP_001130266.1\|2727431_2728007_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
NZ_CP027546.1\|WP_000046800.1\|2746993_2748295_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
NZ_CP027546.1\|WP_000254745.1\|2744050_2744386_-\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NZ_CP027546.1\|WP_000036723.1\|2739937_2741236_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP027546.1\|WP_001071648.1\|2743188_2743980_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP027546.1\|WP_001341835.1\|2729011_2729791_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	3.2021e-62
NZ_CP027546.1\|WP_001164569.1\|2733826_2735104_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	3.54023e-29
NZ_CP027546.1\|WP_001268451.1\|2739005_2739878_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.01855e-100
NZ_CP027546.1\|WP_001098105.1\|2729768_2731106_-\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.74708e-50
NZ_CP027546.1\|WP_000021313.1\|2733413_2733509_-\|hypothetical-protein	gnl\|CDD\|180761	PRK06935, PRK06935, 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD.	9.20529e-11
NZ_CP027546.1\|WP_000581937.1\|2744385_2744634_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP027546.1\|WP_000039758.1\|2735130_2736609_+\|FGGY-family-carbohydrate-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.28272e-107
NZ_CP027546.1\|WP_000109366.1\|2727154_2727415_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	3.33712e-39
NZ_CP027546.1\|WP_000226815.1\|2744711_2746946_-\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP027546.1\|WP_001341834.1\|2728154_2729015_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.55254e-89
NZ_CP027546.1\|WP_000059323.1\|2731199_2732654_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.11123e-80
NZ_CP027546.1\|WP_001199970.1\|2738041_2738713_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.73859e-155

>NZ_CP027546.1|WP_000039758.1|2735130_2736609_+|FGGY-family-carbohydrate-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGSVVCEGKGLLQPMHTPYADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASSVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP027546.1|WP_001164569.1|2733826_2735104_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEVRTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP027546.1|WP_000021313.1|2733413_2733509_-|hypothetical-protein
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLG
>NZ_CP027546.1|WP_001152074.1|2732723_2733404_-|SDR-family-oxidoreductase
MALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>NZ_CP027546.1|WP_000059323.1|2731199_2732654_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPQEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGTDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREVMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP027546.1|WP_001098105.1|2729768_2731106_-|MFS-transporter
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>NZ_CP027546.1|WP_001341835.1|2729011_2729791_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRIEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP027546.1|WP_001341834.1|2728154_2729015_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAVKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>NZ_CP027546.1|WP_001130266.1|2727431_2728007_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP027546.1|WP_000109366.1|2727154_2727415_+|ferredoxin-family-protein
MSVAHNLWRVADAPHIVPADSVERQMVQRLINACPAGLFSLTPEGDLRVDYHGCLECGTCCLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP027546.1|WP_001199970.1|2738041_2738713_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP027546.1|WP_001288227.1|2738851_2738992_+|hypothetical-protein
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNESKITDAAVNLFIQI
>NZ_CP027546.1|WP_001268451.1|2739005_2739878_+|YgcG-family-protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIIVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKFAQGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVYISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGKSYHSDNSGSGGGSSGGGFSGGGGSSGGGGASGRW
>NZ_CP027546.1|WP_000036723.1|2739937_2741236_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP027546.1|WP_000210878.1|2741323_2742961_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP027546.1|WP_001071648.1|2743188_2743980_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP027546.1|WP_000254745.1|2744050_2744386_-|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP027546.1|WP_000581937.1|2744385_2744634_-|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP027546.1|WP_000226815.1|2744711_2746946_-|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP027546.1|WP_000046800.1|2746993_2748295_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVAVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLGSLQVMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLAKQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK

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Crispr_ID: NZ_CP027546_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP027546_3

4478181-4478327

Orphan

Consensus_repeat	Method
GTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP027546_3

>merge|NZ_CP027546|3|4478181-4478327|CRISPRCasFinder
GTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCATGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTGCGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

>NZ_CP027546|3|3|4478181-4478327|CRISPRCasFinder
GTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	TGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTGCGC
GTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP027546.1\|WP_000584109.1\|4480141_4481242_+\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP027546.1\|WP_000256681.1\|4468127_4468721_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP027546.1\|WP_000397144.1\|4478363_4479875_-\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP027546.1\|WP_001059398.1\|4472765_4473269_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP027546.1\|WP_001295681.1\|4481241_4482324_+\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP027546.1\|WP_000583470.1\|4468865_4469318_+\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345
NZ_CP027546.1\|WP_000500687.1\|4467343_4468057_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP027546.1\|WP_000012897.1\|4471128_4472142_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP027546.1\|WP_000002953.1\|4472303_4472720_+\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP027546.1\|WP_001332879.1\|4482442_4483945_-\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP027546.1\|WP_000772685.1\|4485537_4486800_+\|integrase-arm-type-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|170049
NZ_CP027546.1\|WP_001339397.1\|4489898_4490576_+\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|366690
NZ_CP027546.1\|WP_000786398.1\|4477566_4478010_-\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP027546.1\|WP_000061768.1\|4484074_4485094_-\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP027546.1\|WP_000091133.1\|4488022_4489609_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027546.1\|WP_000356577.1\|4487043_4487883_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236817
NZ_CP027546.1\|WP_000230273.1\|4466817_4467213_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100005
NZ_CP027546.1\|WP_000416407.1\|4474711_4477567_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP027546.1\|WP_001074121.1\|4469440_4470952_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP027546.1\|WP_000624622.1\|4490575_4490923_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551

Protein	Function_ID	Function_description	E-value
NZ_CP027546.1\|WP_000584109.1\|4480141_4481242_+\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP027546.1\|WP_000256681.1\|4468127_4468721_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.07846e-09
NZ_CP027546.1\|WP_000397144.1\|4478363_4479875_-\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP027546.1\|WP_001059398.1\|4472765_4473269_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.01499e-18
NZ_CP027546.1\|WP_001295681.1\|4481241_4482324_+\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP027546.1\|WP_000500687.1\|4467343_4468057_-\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	5.2218e-149
NZ_CP027546.1\|WP_000012897.1\|4471128_4472142_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP027546.1\|WP_000002953.1\|4472303_4472720_+\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
NZ_CP027546.1\|WP_001332879.1\|4482442_4483945_-\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP027546.1\|WP_000772685.1\|4485537_4486800_+\|integrase-arm-type-DNA-binding-domain-containing-protein	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	1.50065e-85
NZ_CP027546.1\|WP_001339397.1\|4489898_4490576_+\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	4.24973e-14
NZ_CP027546.1\|WP_000786398.1\|4477566_4478010_-\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	1.88895e-65
NZ_CP027546.1\|WP_000061768.1\|4484074_4485094_-\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	6.7524e-167
NZ_CP027546.1\|WP_000356577.1\|4487043_4487883_-\|hypothetical-protein	gnl\|CDD\|236817	PRK11001, mtlR, MltR family transcriptional regulator.	0.000100827
NZ_CP027546.1\|WP_000230273.1\|4466817_4467213_-\|RidA-family-protein	gnl\|CDD\|100005	cd02198, YjgH_like, YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	3.56238e-58
NZ_CP027546.1\|WP_000416407.1\|4474711_4477567_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP027546.1\|WP_000583470.1\|4468865_4469318_+\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.50239e-70
NZ_CP027546.1\|WP_000624622.1\|4490575_4490923_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	6.55545e-55

>NZ_CP027546.1|WP_000786398.1|4477566_4478010_-|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTCFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP027546.1|WP_000416407.1|4474711_4477567_-|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP027546.1|WP_001059398.1|4472765_4473269_-|GNAT-family-N-acetyltransferase
MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLREL
>NZ_CP027546.1|WP_000002953.1|4472303_4472720_+|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP027546.1|WP_000012897.1|4471128_4472142_-|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGAHVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSKLNN
>NZ_CP027546.1|WP_001074121.1|4469440_4470952_+|hypothetical-protein
MAKISDLNCYQHMASADNVKPKNEVLNTWCVGMNDFARNAEGQDSRRNILSPGAFLEFLAKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMNFVMNNPEGERADSSKVIIEISLSTTTTMGTRQGHTAIIFPQSDFLSFRYEGKSFERKDDSSLHLITNKVLACYQREANKNMALLLNNHQLNWKDAIDYNELLEKPLASTLEKIKKEHLLLMPHVCDDTIPYLLGEGGILEEINDLKALHDTRIASGTEGNDEINNIKINLSNILIDSLDDAKVNLEKVIDSMLKTFLKLPYINDVKILEWCFNQSMQYSDDTTKIKHARSVIDHIDFNCDQSKIAETLFFNLNKEPYKNSPELQELIWEKLVVYVNDFNLSNQEKSRLILRLFDDVKLLFNEVPVSILVNDIFLKDFFMKQPDFAKWYFYQLIKKYEGEQLYLNELGYVYGNEEKTNEIVKKLPGYVIKIFEEKMGNELKIRTRMMKILRNGKINIYKYMNI
>NZ_CP027546.1|WP_000583470.1|4468865_4469318_+|YhcH/YjgK/YiaL-family-protein
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP027546.1|WP_000256681.1|4468127_4468721_+|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKVGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFMSTVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE
>NZ_CP027546.1|WP_000500687.1|4467343_4468057_-|SDR-family-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAEHLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
>NZ_CP027546.1|WP_000230273.1|4466817_4467213_-|RidA-family-protein
MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGTPEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPEKQFEDIMTVKNEIFSAPPYPNWTAVGVTWLAGFDFEIKVIARIPEL
>NZ_CP027546.1|WP_000397144.1|4478363_4479875_-|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP027546.1|WP_000584109.1|4480141_4481242_+|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMCTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP027546.1|WP_001295681.1|4481241_4482324_+|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP027546.1|WP_001332879.1|4482442_4483945_-|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDLMRTDANGKGVINILSAEKLYQMPKLYAASLLWMISELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASIEQQNNPPAKGKEIAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP027546.1|WP_000061768.1|4484074_4485094_-|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDTCISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGTDKVVNSRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF
>NZ_CP027546.1|WP_000772685.1|4485537_4486800_+|integrase-arm-type-DNA-binding-domain-containing-protein
MKLNARQVETAKPKEKTYKMADGGGLYLEVSAKGSKYWRMKYRRPSDKKEDRLAFGVWPMVTLAQARAKRDEAKKLLVQGIDPKAEQKEAQAENSGAYTFETIAREWHASNKRWSEDHRSRILRYLELYIFPHIGSSDIRQLKTSHLLAPIKKVDASGKHDVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTTKARHYPALPSSRFSEFLARLAAYRGRVMTRIAVELSLLTFVRSSELRFARWDEFDFDKSLWRIPAKREEIKGVRYSYRGMKMKEEHIVPLSRQAMVLLEQLKQISGDKELLFPGDHDAAKVMSENTVNSALRAMGYDTKTEVCGHGFRTMARGALGESGLWSDDAIERQLSHTERNNVRAAYIHTSEHLDERRLMVQWWADFLEANRNNSVTPYEFAKFMGK
>NZ_CP027546.1|WP_000356577.1|4487043_4487883_-|hypothetical-protein
MDKDNLFNDLNKLNGYLDSLDERGLILSLAAFSEDALGKMLLTFMLDNKASKELIEGFNAPLGTFSSRIKACFSLGLITEGQYKDLELLRKIRNKFSHSWENISIEDQDISQQIKALSFSRIDFECPKDNYQKIKKSISCLLIEIKITTSQIKKKHLKARLVGSNVNIGFSGKYEEQVNDIKKNIESIKNDLTSHDKNIKSFAVHTANLLIERLSYVQFNHDDLDVFSDQLVDILEIKYQLLNLLGINGVTDLSQKEKEKLKKSFIERITIQTSNVSKK
>NZ_CP027546.1|WP_000091133.1|4488022_4489609_-|hypothetical-protein
MSRRKVGNMGRGDFDRLCNASGLIYNSSSEDDSGGWDAIVEFPLLGGIALLNSLNEQPIQCLVQIKSSDGEKKGVQVKLSNMKRFCDTPLPCFFFFARYNKNANIESAYLVHINSDIMFQVLKRIRQNDIGKKSPLHKLSFTVNYSDEDEIDLTNEYALKNAIEKHIPHGMKKYSEDKLRDLGNVGYNESRYAFNFKVDNNEDYKSLISATLGYPTRINVKDVRGWDTRFDINFQMEELTAEQAIIEIRSVEAFSTGSIIFEDEKEDVSFKCEFFVSPIALNAPRDLASFRICSDFFDLLVGIKNNKLKIDFESYDKPFHLADIRELLLLMKILNAPSGDLKLTIKNNEGNETSFLASDNSFSANPITNEIIKAEQIALALIQVASYFRVDKNCKVSINELIRKQKDIERMHTLISKVPGGYPALRLEIPEHDDNIDSSKELRIFIAIPLIFSSFSICLTCVARGSFTYQNNAMTFNDYEINIEKLIRATNLNELKKQCQAVSDKVNKKFEKDSMDFYYYNSFSQETP
>NZ_CP027546.1|WP_001339397.1|4489898_4490576_+|IS66-family-insertion-sequence-hypothetical-protein
MSIIFNGHYRMKHRTWITEALRLHFEEHLPRVVAGRRLGVPKSTVCSMFVRFRRAGLSWPLPAGMSEQELDACLYGQFSTVPVVRPESTVISEAPVVKKRPRRPNFPYEFKIALVEQSLQPGACVAQIARENGINDNLLFNWRHQYRKGGLLPSGKNMPALLPVTLTPEPDNKIPAPAQEPEQINTPSDSLCCELVLPAGTLRLKGKLTPALLQTLIREIKGSSH
>NZ_CP027546.1|WP_000624622.1|4490575_4490923_+|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MISLPAGSRIWLVAGITDMRNGFNGLASKVQNVLKDDPFSGHLFIFRGRRGDQIKVLWADSDGLCLFTKRLERGRFVWPVTRDGKVHLTPAQLSMLLEGINWKHPKRTERAGIRI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP027546_1	1.1\|2710998\|32\|NZ_CP027546\|CRT	2710998-2711029	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	3	0.906
NZ_CP027546_1	1.2\|2711059\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711059-2711090	32	NZ_CP050442	Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence	41503-41534	6	0.812
NZ_CP027546_1	1.1\|2710998\|32\|NZ_CP027546\|CRT	2710998-2711029	32	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	112768-112799	7	0.781
NZ_CP027546_1	1.1\|2710998\|32\|NZ_CP027546\|CRT	2710998-2711029	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1428097-1428128	8	0.75
NZ_CP027546_1	1.6\|2711303\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711303-2711334	32	NZ_CP030355	Novosphingobium sp. P6W plasmid pP6W2, complete sequence	141173-141204	8	0.75
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NC_012852	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132504, complete sequence	256608-256639	8	0.75
NZ_CP027546_1	1.1\|2710998\|32\|NZ_CP027546\|CRT	2710998-2711029	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	141278-141309	9	0.719
NZ_CP027546_1	1.4\|2711181\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711181-2711212	32	LT599585	Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid	32377-32408	9	0.719
NZ_CP027546_1	1.7\|2711364\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711364-2711395	32	NC_010553	Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence	292180-292211	9	0.719
NZ_CP027546_1	1.7\|2711364\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711364-2711395	32	NZ_CP020740	[Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence	20747-20778	9	0.719
NZ_CP027546_2	2.2\|2737338\|32\|NZ_CP027546\|CRISPRCasFinder	2737338-2737369	32	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	224876-224907	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP050094	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence	196778-196809	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP050101	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b6, complete sequence	151768-151799	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP050106	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence	508685-508716	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP025016	Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence	133778-133809	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NC_008379	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence	180274-180305	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP053442	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eD, complete sequence	151061-151092	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP018233	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence	21422-21453	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP025506	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence	499023-499054	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP016293	Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence	106143-106174	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP050111	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence	508869-508900	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP048283	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence	130036-130067	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP030763	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence	172635-172666	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP022668	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence	387130-387161	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP022569	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence	4795-4826	9	0.719
NZ_CP027546_2	2.7\|2737642\|32\|NZ_CP027546\|CRISPRCasFinder	2737642-2737673	32	NZ_CP050088	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence	158950-158981	9	0.719
NZ_CP027546_1	1.6\|2711303\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711303-2711334	32	MF417892	Uncultured Caudovirales phage clone 2F_2, partial genome	39822-39853	10	0.688
NZ_CP027546_1	1.8\|2711425\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711425-2711456	32	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	903982-904013	10	0.688
NZ_CP027546_1	1.8\|2711425\|32\|NZ_CP027546\|CRT,PILER-CR,CRISPRCasFinder	2711425-2711456	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1467285-1467316	11	0.656

1. spacer 1.1|2710998|32|NZ_CP027546|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 3, identity: 0.906

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
caagtgatgtccatcatcgcatccagtgcgtc	Protospacer
.*******.*********************.*

2. spacer 1.2|2711059|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP050442 (Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

aaaaccaaacttctccataaattccatagccg	CRISPR spacer
attactaaacttctgcataaattccataggag	Protospacer
*  **.******** **************  *

3. spacer 1.1|2710998|32|NZ_CP027546|CRT matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 7, identity: 0.781

taagtgat-atccatcatcgcatccagtgcgcc	CRISPR spacer
-ggttgatcgtccttcatcgcagccagtgcgcc	Protospacer
 .. **** .*** ******** **********

4. spacer 1.1|2710998|32|NZ_CP027546|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

taagtg---atatccatcatcgcatccagtgcgcc	CRISPR spacer
---gtgcgcccctccatcaccgcttccagtgcgcc	Protospacer
   ***    . *******.*** ***********

5. spacer 1.6|2711303|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP030355 (Novosphingobium sp. P6W plasmid pP6W2, complete sequence) position: , mismatch: 8, identity: 0.75

tcttcgcgggtaatcaatgatgattcagtttc	CRISPR spacer
tcttcgcggataatcaaagatgatcgtgaatt	Protospacer
*********.******* ******.  *  *.

6. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NC_012852 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132504, complete sequence) position: , mismatch: 8, identity: 0.75

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggtgctgtcgggagcggggaggatgagagaat	Protospacer
. *.******* *** ***********...**

7. spacer 1.1|2710998|32|NZ_CP027546|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 9, identity: 0.719

taagtgatatccatcatcgcatccagtgcgcc	CRISPR spacer
ctcatcgcatccatcatcggttccagtgcgcc	Protospacer
.  .* ..***********  ***********

8. spacer 1.4|2711181|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to LT599585 (Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid) position: , mismatch: 9, identity: 0.719

gagagtgctgacaggtgtctcgattacctgat	CRISPR spacer
ggctttgctggcaggtctctcgattaccttgg	Protospacer
*.   *****.***** ************ .

9. spacer 1.7|2711364|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to NC_010553 (Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence) position: , mismatch: 9, identity: 0.719

gaacgcaatatcacggcgttctgcggcctcgg	CRISPR spacer
atcggcaatatcacggcgtttttcggcgccgc	Protospacer
.   ****************.* **** .**

10. spacer 1.7|2711364|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP020740 ([Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence) position: , mismatch: 9, identity: 0.719

gaacgcaatatcacggcgttctgcggcctcgg	CRISPR spacer
accggcaacatcacggcgttcttcggcgccgc	Protospacer
.   ****.************* **** .**

11. spacer 2.2|2737338|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcatagccaggctgatccggcgacggcctta	CRISPR spacer
gcagcagaccggctgatccggcgacggccccg	Protospacer
*  ..** * *******************...

12. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP050094 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b4, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

13. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP050101 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b6, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

14. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP050106 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

15. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP025016 (Rhizobium leguminosarum strain Norway plasmid pRLN4, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

16. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NC_008379 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL9, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

17. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP053442 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eD, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

18. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP018233 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

19. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP025506 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

20. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP016293 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

21. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP050111 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

22. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP048283 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248c, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

23. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP030763 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

24. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP022668 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

25. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP022569 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

26. spacer 2.7|2737642|32|NZ_CP027546|CRISPRCasFinder matches to NZ_CP050088 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence) position: , mismatch: 9, identity: 0.719

actactgtcggtagctgggaggatgaggagat	CRISPR spacer
ggcgctgtcgggagcggggaggatgagagaat	Protospacer
. ..******* *** ***********...**

27. spacer 1.6|2711303|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to MF417892 (Uncultured Caudovirales phage clone 2F_2, partial genome) position: , mismatch: 10, identity: 0.688

tcttcgcgggtaatcaatgatgattcagtttc	CRISPR spacer
cagttgcaggtaatcaatgatgatgcagccca	Protospacer
.  *.**.**************** ***...

28. spacer 1.8|2711425|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.688

caaaatattacgagcttcgtcaggccatggac	CRISPR spacer
tcttgcatcacgagcttcgtcaggacatgcgc	Protospacer
.   ..**.*************** **** .*

29. spacer 1.8|2711425|32|NZ_CP027546|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.656

caaaatattacgagcttcgtcaggccatggac	CRISPR spacer
tcttgcatcacgagcttcgtcaggacatgcgg	Protospacer
.   ..**.*************** **** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

26481 : 80004

Enterobacteria_phage(48.53%)

lysis,holin,transposase,terminase,head,tail,integrase,portal,protease

attL 22229:22244|attR 29300:29315

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
22229:22244	attL	NA	NA	NA	NA
WP_000533654.1\|26481_27552_-\|integrase	tyrosine-type recombinase/integrase	K7P6P6	Enterobacteria_phage	5.6e-201	99.4
WP_001303849.1\|27529_27748_-	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_001281774.1\|27854_28199_-	hypothetical protein	K7PJY7	Enterobacterial_phage	4.5e-59	98.2
WP_000545733.1\|28227_28395_-	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	1.3e-27	100.0
WP_000002107.1\|28467_28752_-	ASCH domain-containing protein	A0A2D1GLL3	Escherichia_phage	1.8e-50	100.0
WP_012817743.1\|28744_29047_-	restriction alleviation protein, Lar family	Q716F5	Shigella_phage	9.4e-53	97.0
WP_000104414.1\|29043_29661_-	hypothetical protein	Q716F4	Shigella_phage	5.6e-36	64.2
29300:29315	attR	NA	NA	NA	NA
WP_000034231.1\|29662_30220_-	ead/Ea22-like family protein	A5VWB3	Enterobacteria_phage	4.6e-45	83.6
WP_000812206.1\|30216_30774_-	hypothetical protein	E7C9P6	Salmonella_phage	3.2e-62	64.3
WP_001214436.1\|30770_30935_-	DUF2737 family protein	K7P7R0	Enterobacteria_phage	4.2e-23	98.1
WP_001111278.1\|30945_31239_-	DUF2856 family protein	G8C7L1	Escherichia_phage	2.5e-50	99.0
WP_000951334.1\|31262_31646_-	hypothetical protein	K7P6P8	Enterobacteria_phage	2.5e-66	98.4
WP_000031370.1\|31645_32251_-	ERF family protein	Q9MCQ9	Enterobacteria_phage	4.1e-108	100.0
WP_001243354.1\|32507_32660_-	host cell division inhibitory peptide Kil	A5VWA5	Enterobacteria_phage	1.5e-19	98.0
WP_000638547.1\|32644_32776_-\|protease	protease FtsH-inhibitory lysogeny factor CIII	A5VWA4	Enterobacteria_phage	1.4e-16	100.0
WP_085948186.1\|33263_34420_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_000073663.1\|35291_35831_+	superinfection exclusion protein B	A0A192Y7Z0	Salmonella_phage	8.1e-39	44.9
WP_000088201.1\|35854_36127_-	hypothetical protein	A0A0N7C217	Escherichia_phage	7.4e-41	98.9
WP_000193240.1\|36733_37096_-	hypothetical protein	A0A1P8DTD0	Proteus_phage	6.2e-19	51.4
WP_000428099.1\|37364_38069_-	helix-turn-helix transcriptional regulator	A0A0P0ZE37	Stx2-converting_phage	4.3e-133	99.6
WP_000064150.1\|38182_38416_+	hypothetical protein	A0A0P0ZDD7	Stx2-converting_phage	4.0e-35	97.4
WP_000438538.1\|38554_38854_+	hypothetical protein	A0A0P0ZBJ0	Stx2-converting_phage	4.8e-49	99.0
WP_000185473.1\|38886_39825_+	replication protein	O48421	Enterobacteria_phage	1.4e-171	99.7
WP_000788880.1\|39821_40523_+	Replication protein P	K7P6G2	Enterobacteria_phage	3.8e-129	99.1
WP_000145926.1\|40519_40810_+	protein ren	O48423	Enterobacteria_phage	9.6e-47	100.0
WP_000344573.1\|41106_41463_+	hypothetical protein	K7PHN9	Enterobacterial_phage	2.1e-59	97.3
WP_085948186.1\|41733_42889_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_001254255.1\|43108_43285_+	NinE family protein	A5VW90	Enterobacteria_phage	4.6e-28	100.0
WP_000924601.1\|43287_43689_+	hypothetical protein	Q9EYC4	Enterobacteria_phage	1.4e-72	100.0
WP_001341811.1\|43648_43858_+	protein ninF	G9L691	Escherichia_phage	2.6e-30	97.1
WP_001003989.1\|43850_44573_+	DNA-binding protein	K7P6K2	Enterobacteria_phage	5.4e-131	99.6
WP_000002261.1\|44572_44863_+	DUF1364 domain-containing protein	A0A192Y6R9	Salmonella_phage	2.9e-51	97.9
WP_001008193.1\|44859_45222_+	RusA family crossover junction endodeoxyribonuclease	A5VW85	Enterobacteria_phage	2.7e-62	99.2
WP_000994516.1\|45218_45407_+	protein ninH	A5VW84	Enterobacteria_phage	5.5e-27	100.0
WP_000750155.1\|45618_46578_-	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_032160865.1\|46915_47038_+	YlcG family protein	NA	NA	NA	NA
WP_001097238.1\|47052_47742_+	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.5e-58	48.1
WP_001302581.1\|47926_48670_+	hypothetical protein	NA	NA	NA	NA
WP_000499454.1\|48755_48914_+	DUF3927 family protein	NA	NA	NA	NA
WP_000411802.1\|51524_51731_+\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000075132.1\|51730_52228_+	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_000092325.1\|52224_52662_+\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	1.7e-71	98.6
WP_000881326.1\|52811_53429_+	hypothetical protein	A0A1R3Y613	Salmonella_virus	6.5e-93	85.9
WP_001307652.1\|53616_53811_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
WP_000235451.1\|54206_54716_+\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.2e-12	33.3
WP_009442816.1\|54687_56616_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	2.7e-262	66.4
WP_000259002.1\|56599_56806_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_106889257.1\|56802_58395_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	3.5e-183	60.9
WP_001254029.1\|58384_58561_+	hypothetical protein	E4WL22	Enterobacteria_phage	1.1e-08	56.4
WP_000839179.1\|58638_59043_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_000612626.1\|59039_59387_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000099160.1\|59435_60974_+\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_032284507.1\|60970_61339_+	hypothetical protein	A0A0K2FIF4	Enterobacteria_phage	2.4e-50	88.0
WP_001143013.1\|61346_62099_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.7e-127	93.6
WP_000479086.1\|62112_62544_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	4.8e-42	68.1
WP_000533431.1\|62570_62984_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.0e-41	82.8
WP_000082320.1\|62964_65544_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	82.3
WP_000847304.1\|65540_65870_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	2.2e-55	95.4
WP_032325234.1\|65869_66568_+\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	2.4e-131	98.3
WP_069358375.1\|66578_67322_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.9e-148	98.8
WP_096844540.1\|67267_67900_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-102	91.8
WP_106913804.1\|68135_71528_+	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	84.1
WP_001230449.1\|71595_72195_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	2.6e-110	98.5
WP_000268998.1\|72259_73474_+	short-chain dehydrogenase	B6DZB7	Enterobacteria_phage	6.6e-81	95.8
WP_001023459.1\|73475_73745_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	4.6e-43	96.6
WP_000950982.1\|73850_74732_+	hypothetical protein	A5LH48	Enterobacteria_phage	3.9e-147	90.4
WP_000652081.1\|74955_75783_+	type III secretion system effector Cif	A5LH49	Enterobacteria_phage	3.1e-154	98.2
WP_021351651.1\|75906_76278_-	hypothetical protein	K7PH54	Enterobacteria_phage	1.1e-58	95.1
WP_000381395.1\|76752_78324_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|78343_78691_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|78690_79368_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_001448642.1\|79428_80004_+	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	1.6e-77	77.5

DBSCAN-SWA_2

295107 : 408095

146

Escherichia_phage(33.63%)

capsid,holin,terminase,transposase,head,tail,integrase,portal,protease

attL 314768:314786|attR 361821:361839

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000156528.1\|295107_296868_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000877161.1\|297053_297506_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_000750416.1\|297580_298621_-	porin OmpA	NA	NA	NA	NA
WP_000288710.1\|298977_299487_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_000839153.1\|299705_300335_+	CRP-S regulon transcriptional coactivator Sxy	NA	NA	NA	NA
WP_000875023.1\|300297_302460_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_001261235.1\|302469_302916_-	YccF domain-containing protein	NA	NA	NA	NA
WP_001297106.1\|303038_305093_+	DNA helicase IV	A7KV33	Bacillus_phage	7.7e-21	27.9
WP_000424181.1\|305124_305583_-	methylglyoxal synthase	NA	NA	NA	NA
WP_000847791.1\|305678_306341_-	DUF2057 family protein	NA	NA	NA	NA
WP_000665217.1\|306513_306927_+	CoA-binding protein	NA	NA	NA	NA
WP_001295356.1\|306971_307289_-	heat shock protein HspQ	NA	NA	NA	NA
WP_000116301.1\|307346_308537_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_000048244.1\|308631_308910_+	acylphosphatase	NA	NA	NA	NA
WP_000904442.1\|308906_309236_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_000375138.1\|309326_309986_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	5.2e-48	54.9
WP_001299351.1\|310393_311413_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.3e-85	49.7
WP_000273151.1\|311390_311633_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_009448824.1\|311700_314151_-	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.6
WP_001098307.1\|314244_314436_-	DUF1482 family protein	NA	NA	NA	NA
WP_000413705.1\|314432_314621_-	cell division inhibition protein DicB	NA	NA	NA	NA
314768:314786	attL	NA	NA	NA	NA
WP_001133037.1\|315188_315398_+	hypothetical protein	NA	NA	NA	NA
WP_000394548.1\|315398_316037_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_001345283.1\|316048_316201_-	DUF1391 family protein	M4QQ57	Salicola_phage	1.7e-07	53.2
WP_000362152.1\|316467_316887_-	hypothetical protein	K7PK07	Enterobacteria_phage	4.0e-25	65.1
WP_000391948.1\|316986_317268_+	hypothetical protein	K7PHA1	Enterobacteria_phage	8.5e-24	72.6
WP_000693883.1\|317251_317677_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_025380294.1\|317748_318855_+	hypothetical protein	A0A088CD36	Shigella_phage	1.8e-64	65.7
WP_021498074.1\|318861_319602_+	ATP-binding protein	A0A088CBP4	Shigella_phage	4.6e-125	90.2
WP_032324560.1\|319627_320398_+	DUF1627 domain-containing protein	A0A088CE47	Shigella_phage	2.5e-86	68.5
WP_001151235.1\|320413_320836_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.6e-64	90.6
WP_000935423.1\|320941_321154_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.6e-36	97.1
WP_000209148.1\|321186_321405_+	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	5.2e-29	91.7
WP_000224233.1\|321406_321670_+	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
WP_000208016.1\|321680_322550_+	DUF551 domain-containing protein	A0A1U9AJ59	Stx1_converting_phage	8.5e-123	79.2
WP_001278454.1\|322665_322770_+	hypothetical protein	NA	NA	NA	NA
WP_000018421.1\|322959_323172_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	8.1e-27	92.9
WP_001341388.1\|323339_323618_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265133.1\|323619_324669_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	3.4e-110	54.9
WP_001217436.1\|324681_325053_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_000090265.1\|325042_325414_+	antitermination protein	Q777W5	Enterobacteria_phage	1.0e-53	84.0
WP_000265267.1\|325565_326384_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000917737.1\|326670_326868_+	hypothetical protein	S5MQK8	Escherichia_phage	2.6e-27	96.9
WP_000261909.1\|327005_327719_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000874348.1\|328486_330337_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.3
WP_000411814.1\|330785_330992_+\|holin	holin	Q6H9V8	Enterobacteria_phage	5.3e-31	98.5
WP_000138558.1\|331247_331520_-	hypothetical protein	NA	NA	NA	NA
WP_001003111.1\|331679_332213_+	lysozyme	A0A1U9AJ98	Stx1_converting_phage	1.4e-99	94.9
WP_000675931.1\|332433_332547_+	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_012816791.1\|332768_332954_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_001303878.1\|333481_333796_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001300236.1\|333877_334102_-	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	2.9e-19	88.7
WP_000453587.1\|334498_335044_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_001027379.1\|335018_336944_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.1
WP_000198153.1\|336940_337147_+\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001415980.1\|337143_338745_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	2.3e-307	98.5
WP_000123251.1\|338725_340045_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	7.6e-232	97.9
WP_001365129.1\|340054_340387_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.5e-54	98.2
WP_000063258.1\|340442_341468_+\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	5.1e-191	98.8
WP_000158897.1\|341509_341905_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.4e-56	93.9
WP_000752994.1\|341916_342270_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.0e-63	100.0
WP_000975098.1\|342281_342860_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.0e-79	98.4
WP_000683137.1\|342856_343252_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	3.7e-65	92.4
WP_000235067.1\|343259_344012_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.2e-133	98.4
WP_000479051.1\|344025_344448_+\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	2.4e-70	97.9
WP_000533442.1\|344474_344888_+\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_000081792.1\|344868_347481_+\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	96.0
WP_000847298.1\|347477_347807_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_001443841.1\|347806_348505_+\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	4.4e-130	97.4
WP_069358375.1\|348515_349259_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.9e-148	98.8
WP_096844540.1\|349204_349837_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-102	91.8
WP_106913809.1\|350072_353555_+	host specificity protein J	Q6H9T2	Enterobacteria_phage	0.0e+00	94.0
WP_032271866.1\|353623_354247_+	Ail/Lom family outer membrane beta-barrel protein	A0A1U8QHD6	Enterobacteria_phage	8.7e-69	60.9
WP_106881528.1\|354311_355625_+\|tail	phage tail protein	Q9EYE8	Enterobacteria_phage	8.5e-74	97.9
WP_001023455.1\|355626_355896_+\|tail	phage tail protein	Q687E5	Enterobacteria_phage	2.4e-44	98.9
WP_012817749.1\|356020_356773_-	type III effector	NA	NA	NA	NA
WP_001299351.1\|357576_358596_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.3e-85	49.7
WP_000273151.1\|358573_358816_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_106889259.1\|358883_361334_-	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.6
WP_000199475.1\|361429_361618_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449175.1\|361614_361803_-	cell division inhibitor	NA	NA	NA	NA
WP_001331716.1\|362203_362368_+	hypothetical protein	NA	NA	NA	NA
361821:361839	attR	NA	NA	NA	NA
WP_001171921.1\|362371_362590_-	hypothetical protein	NA	NA	NA	NA
WP_024182289.1\|362682_362883_+	hypothetical protein	NA	NA	NA	NA
WP_000692026.1\|363296_363599_+	type II toxin-antitoxin system HigB family toxin	A0A0P0ZE17	Stx2-converting_phage	3.7e-17	43.3
WP_001022415.1\|363601_363961_+	helix-turn-helix domain-containing protein	A0A222YXG1	Escherichia_phage	3.6e-59	93.3
WP_000578360.1\|364007_364400_-	helix-turn-helix domain-containing protein	H6WRX4	Salmonella_phage	1.7e-14	39.6
WP_001172789.1\|364526_364787_+	transcriptional regulator	H6WRX5	Salmonella_phage	4.8e-21	64.8
WP_000693932.1\|364783_365221_+	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	1.6e-29	55.0
WP_000729535.1\|365307_366318_+	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	4.9e-170	88.8
WP_072096947.1\|366229_366772_+	replication protein	A0A0U2JGJ0	Escherichia_phage	1.8e-78	89.5
WP_000450641.1\|366805_367531_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.2e-77	63.4
WP_001040234.1\|367546_367939_+	DUF977 family protein	A0A088CBK9	Shigella_phage	1.0e-38	62.6
WP_001266133.1\|367935_368232_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	5.8e-47	94.7
WP_001209480.1\|368228_368690_+	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	3.4e-38	92.9
WP_000403783.1\|368667_369024_+	hypothetical protein	A0A2R2Z307	Escherichia_phage	4.6e-59	100.0
WP_000935422.1\|369074_369287_+	hypothetical protein	A0A2R2Z310	Escherichia_phage	6.6e-37	100.0
WP_001224662.1\|369320_369503_+	hypothetical protein	A0A2R2Z308	Escherichia_phage	1.4e-27	100.0
WP_001289353.1\|369668_370304_+	ead/Ea22-like family protein	A0A2R2Z315	Escherichia_phage	1.3e-115	100.0
WP_000209152.1\|370391_370610_+	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	6.6e-32	100.0
WP_001229296.1\|370611_370977_+	HNH endonuclease	A0A2R2Z2X9	Escherichia_phage	5.1e-69	100.0
WP_000206830.1\|370973_371318_+	hypothetical protein	A0A2R2Z2X8	Escherichia_phage	1.7e-58	100.0
WP_000220601.1\|371522_371822_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A2R2Z2Y1	Escherichia_phage	1.8e-51	100.0
WP_001260977.1\|371827_372085_-	type II toxin-antitoxin system ParD family antitoxin	A0A0N7C055	Escherichia_phage	1.5e-30	86.7
WP_001342259.1\|372220_372493_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.2e-10	47.5
WP_001265113.1\|372494_373541_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.4e-108	54.5
WP_000904103.1\|373553_373913_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.8e-34	60.0
WP_000640048.1\|373921_374452_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	9.3e-72	72.6
WP_000917770.1\|374693_374891_+	hypothetical protein	S5MQK8	Escherichia_phage	8.9e-28	96.9
WP_000301785.1\|375025_375739_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000466957.1\|376188_376620_+	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	3.3e-67	97.2
WP_085948186.1\|378822_379978_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_122368378.1\|380032_380302_+	hypothetical protein	A0A0P0ZBP4	Stx2-converting_phage	2.1e-43	98.9
WP_000143463.1\|380437_380617_+	DUF1378 family protein	Q5MBW3	Stx1-converting_phage	4.4e-26	100.0
WP_001290230.1\|380657_380903_+	DUF826 domain-containing protein	A0A0P0ZGR2	Escherichia_phage	8.8e-17	100.0
WP_001072901.1\|380980_381196_+\|holin	holin	A0A2R2Z340	Escherichia_phage	1.2e-33	100.0
WP_000087714.1\|381200_381734_+	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.0e-102	99.4
WP_001056883.1\|382008_382578_+	hypothetical protein	A0A2R2Z339	Escherichia_phage	1.5e-104	99.5
WP_000455402.1\|382577_382727_+	hypothetical protein	A0A0P0ZFU6	Escherichia_phage	9.1e-17	98.0
WP_001208680.1\|382954_383140_+	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_001302717.1\|383666_383981_+	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001448509.1\|384062_384287_-	YlcI/YnfO family protein	A0A0P0ZE23	Stx2-converting_phage	2.9e-19	76.1
WP_000279796.1\|384328_384694_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	3.1e-66	100.0
WP_000958380.1\|384986_385550_+\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_033816804.1\|385546_387208_+\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.5
WP_000173079.1\|387271_389209_+\|capsid	phage major capsid protein	A0A0P0ZCT9	Stx2-converting_phage	0.0e+00	100.0
WP_001063025.1\|389253_389475_+	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_032325002.1\|392001_392328_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	1.2e-53	99.1
WP_001007905.1\|392338_392689_+\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_000573391.1\|392685_393132_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_000133388.1\|393128_393473_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_106881370.1\|393538_394255_+\|tail	phage tail protein	A0A0P0ZD29	Stx2-converting_phage	3.1e-126	98.3
WP_001030063.1\|394260_394635_+\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001453698.1\|394730_394940_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_106889265.1\|394991_398234_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	94.2
WP_000807940.1\|398226_398568_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.7e-61	97.3
WP_001335877.1\|398567_399266_+\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	1.7e-129	96.6
WP_001429308.1\|399271_400015_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	1.5e-147	98.4
WP_096844540.1\|399960_400593_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	3.5e-102	91.8
WP_106913810.1\|400828_404305_+	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	97.3
WP_001230429.1\|404371_404971_+	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	2.3e-111	99.0
WP_000279017.1\|405035_406349_+\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	7.4e-78	98.9
WP_001023995.1\|406350_406620_+\|tail	phage tail protein	A0A0P0ZCV7	Stx2-converting_phage	7.1e-44	95.5
WP_000767050.1\|406841_407384_+	hypothetical protein	Q9LA55	Enterobacteria_phage	8.4e-52	68.6
WP_106420821.1\|407328_407523_+	hypothetical protein	A0A2R2Z347	Escherichia_phage	4.1e-09	84.6
WP_001131653.1\|407513_408095_+	T3SS effector NleG family protein	H6WZN1	Escherichia_phage	5.1e-63	64.2

DBSCAN-SWA_3

723797 : 774462

Stx2-converting_phage(29.79%)

capsid,integrase,holin,terminase,head,tail,transposase

attL 720902:720916|attR 780312:780326

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
720902:720916	attL	NA	NA	NA	NA
WP_000113674.1\|723797_724928_-\|integrase	tyrosine-type recombinase/integrase	O21940	Phage_21	3.4e-103	51.4
WP_000113189.1\|724905_725154_-	excisionase	NA	NA	NA	NA
WP_000048478.1\|725218_727690_-	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.2
WP_000199480.1\|727785_727974_-	DUF1482 family protein	NA	NA	NA	NA
WP_000449172.1\|727970_728159_-	cell division inhibitor	NA	NA	NA	NA
WP_001342117.1\|728558_728726_+	hypothetical protein	NA	NA	NA	NA
WP_000920491.1\|728719_728953_+	hypothetical protein	NA	NA	NA	NA
WP_000394552.1\|728930_729338_-	hypothetical protein	A0A2R2Z306	Escherichia_phage	7.0e-11	37.8
WP_001171903.1\|729360_729579_-	hypothetical protein	NA	NA	NA	NA
WP_001240336.1\|729651_729951_-	hypothetical protein	NA	NA	NA	NA
WP_000787428.1\|730215_730623_-	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	9.8e-29	49.6
WP_000912298.1\|730699_730927_+	transcriptional regulator	NA	NA	NA	NA
WP_000705622.1\|730910_731462_+	hypothetical protein	NA	NA	NA	NA
WP_000020556.1\|731433_732474_+	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_157825328.1\|732385_732928_+	replication protein	A0A0U2JGJ0	Escherichia_phage	1.5e-85	98.7
WP_001505071.1\|733691_733856_+	hypothetical protein	NA	NA	NA	NA
WP_001449026.1\|734554_735313_+	AcfC family adhesin Paa	NA	NA	NA	NA
WP_000961821.1\|735591_735804_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.3e-16	72.9
WP_001217394.1\|736024_736282_+	hypothetical protein	NA	NA	NA	NA
WP_106913812.1\|736351_736630_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265290.1\|736631_737687_+	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.9e-88	47.6
WP_000140002.1\|737687_738053_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.6e-38	67.5
WP_032324106.1\|738049_738739_+	antiterminator	I6PDF8	Cronobacter_phage	1.8e-59	51.5
WP_000023141.1\|740259_742113_+	SASA family carbohydrate esterase	H6WZJ9	Escherichia_phage	0.0e+00	96.6
WP_000284522.1\|742262_742478_+\|holin	holin	Q6H9V8	Enterobacteria_phage	1.3e-32	97.2
WP_032325202.1\|742482_742827_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	7.9e-56	96.5
WP_000992088.1\|742877_743411_+	lysozyme	B6DZ92	Enterobacteria_phage	5.6e-101	98.3
WP_001056803.1\|743681_744248_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	2.9e-103	99.5
WP_000539792.1\|744247_744394_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001208682.1\|744621_744828_+	hypothetical protein	H6WRZ6	Salmonella_phage	7.1e-12	64.7
WP_000735655.1\|744892_745117_+	hypothetical protein	NA	NA	NA	NA
WP_085948186.1\|745211_746367_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_000347013.1\|746740_746881_+	hypothetical protein	NA	NA	NA	NA
WP_001428130.1\|747010_747196_-	YlcI/YnfO family protein	H6WZK6	Escherichia_phage	1.3e-20	92.3
WP_000829192.1\|747237_747603_+	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
WP_000958380.1\|747891_748455_+\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_062890118.1\|748451_750113_+\|terminase	terminase large subunit	A0A0P0ZEI4	Stx2-converting_phage	0.0e+00	99.1
WP_044165196.1\|750176_752114_+\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	99.1
WP_001063096.1\|752158_752380_+	hypothetical protein	H6WZL1	Escherichia_phage	3.4e-36	100.0
WP_000125984.1\|754906_755233_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
WP_001007911.1\|755242_755593_+\|head	phage head closure protein	H6WZL5	Escherichia_phage	2.0e-59	100.0
WP_000573391.1\|755589_756036_+	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_000133393.1\|756032_756377_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_001275479.1\|756445_757162_+\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	4.0e-126	97.5
WP_001030060.1\|757167_757542_+\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	3.0e-64	99.2
WP_001453698.1\|757637_757847_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_106913813.1\|757898_761141_+\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	99.5
WP_000807927.1\|761133_761475_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.3e-62	98.2
WP_025404404.1\|761474_762173_+\|tail	phage minor tail protein L	S5M7Q4	Escherichia_phage	8.9e-131	97.4
WP_106889273.1\|762178_762922_+\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	7.0e-150	98.8
WP_064755952.1\|762867_763500_+\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	1.4e-103	92.3
WP_000649829.1\|763690_764218_-	superoxide dismutase family protein	Q9MC02	Salmonella_phage	1.8e-59	60.5
WP_106913814.1\|764351_767849_+	host specificity protein J	A0A0P0ZEQ8	Stx2-converting_phage	0.0e+00	94.2
WP_001230550.1\|767919_768519_+	Ail/Lom family outer membrane beta-barrel protein	B6ETG5	Enterobacteria_phage	3.0e-111	100.0
WP_106913815.1\|768583_769789_+\|tail	phage tail protein	B6DZB7	Enterobacteria_phage	7.3e-80	95.8
WP_001023992.1\|769790_770060_+\|tail	phage tail protein	A0A0P0ZCV7	Stx2-converting_phage	4.2e-44	95.5
WP_001131659.1\|770172_770748_+	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	5.3e-89	88.4
WP_001443810.1\|770820_771450_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.3e-77	92.2
WP_001143784.1\|771531_772173_+	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	6.8e-109	100.0
WP_001295593.1\|772753_773188_-	universal stress protein UspF	A0A1W6JNV4	Morganella_phage	1.4e-28	52.8
WP_000837924.1\|773328_774462_-	porin OmpN	Q1MVN1	Enterobacteria_phage	8.3e-118	58.8
780312:780326	attR	NA	NA	NA	NA

DBSCAN-SWA_4

919710 : 1033912

115

Escherichia_phage(41.18%)

capsid,tRNA,terminase,holin,integrase,head,tail,transposase

attL 904032:904047|attR 1031659:1031674

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
904032:904047	attL	NA	NA	NA	NA
WP_085948178.1\|919710_920923_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	1.7e-169	99.7
WP_000520676.1\|921190_922105_-	fimbrial protein	NA	NA	NA	NA
WP_000825452.1\|922163_922667_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_000876763.1\|922679_923210_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_000123648.1\|923223_925875_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_001195166.1\|925916_926627_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_001296758.1\|926987_927551_-	fimbrial protein	NA	NA	NA	NA
WP_001125458.1\|928502_929825_-	type II toxin-antitoxin system serine/threonine protein kinase toxin HipA	NA	NA	NA	NA
WP_001296726.1\|929824_930091_-	type II toxin-antitoxin system antitoxin HipB	NA	NA	NA	NA
WP_000127325.1\|930313_930793_-	autotransporter outer membrane beta-barrel domain-containing protein	A0A2L1IV18	Escherichia_phage	1.7e-43	54.7
WP_000154339.1\|937688_938642_-	transcriptional regulator LsrR	NA	NA	NA	NA
WP_001194888.1\|938890_940426_+	autoinducer 2 ABC transporter ATP-binding protein LsrA	A0A2H4PQG7	Staphylococcus_phage	1.7e-20	30.4
WP_000911171.1\|940419_941448_+	autoinducer 2 ABC transporter permease LsrC	NA	NA	NA	NA
WP_001222721.1\|941447_942440_+	autoinducer 2 ABC transporter permease LsrD	NA	NA	NA	NA
WP_000172466.1\|942451_943474_+	autoinducer 2 ABC transporter substrate-binding protein LsrB	NA	NA	NA	NA
WP_000774200.1\|943500_944370_+	3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase	NA	NA	NA	NA
WP_072097594.1\|944323_944830_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_001341531.1\|944833_945748_-	hypothetical protein	NA	NA	NA	NA
WP_000854640.1\|945954_947406_-	tagaturonate reductase	NA	NA	NA	NA
WP_000558044.1\|947632_949051_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.4e-18	36.1
WP_001191027.1\|949189_949549_-	DUF4186 domain-containing protein	NA	NA	NA	NA
WP_000257409.1\|949548_950475_-	glutaminase B	NA	NA	NA	NA
WP_001296740.1\|950538_951927_-	succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000366496.1\|952027_952909_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001323836.1\|952986_953445_+	putative protein YneK	NA	NA	NA	NA
WP_001341528.1\|953393_954101_+	putative protein YneK	NA	NA	NA	NA
WP_000210799.1\|954250_955441_+	L-arabinose MFS transporter	NA	NA	NA	NA
WP_000885033.1\|955465_956131_-	NAAT family transporter MarC	NA	NA	NA	NA
WP_000843419.1\|956342_956777_+	multiple antibiotic resistance transcriptional regulator MarR	NA	NA	NA	NA
WP_000091199.1\|956796_957180_+	MDR efflux pump AcrAB transcriptional activator MarA	D0R0F8	Streptococcus_phage	4.7e-09	32.3
WP_000803659.1\|957211_957430_+	multiple antibiotic resistance protein MarB	NA	NA	NA	NA
WP_085948186.1\|957889_959045_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_001022772.1\|960217_961891_-	carbohydrate porin	NA	NA	NA	NA
WP_001296721.1\|961946_962258_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_001375402.1\|962285_963608_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_000722571.1\|963722_964034_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_000577179.1\|964232_964931_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000087216.1\|964975_965875_-	O-acetylserine/cysteine exporter	NA	NA	NA	NA
WP_001054196.1\|966069_967257_+	efflux MFS transporter YdeE	NA	NA	NA	NA
WP_000901367.1\|967383_967479_+	protein MgtS	NA	NA	NA	NA
WP_000671731.1\|969617_970010_-	YdeI family stress tolerance OB fold protein	NA	NA	NA	NA
WP_001024559.1\|970285_970804_+	2-oxo-tetronate isomerase	NA	NA	NA	NA
WP_001341522.1\|970848_972894_-	peptidyl-dipeptidase Dcp	NA	NA	NA	NA
WP_000636571.1\|973030_973777_+	bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG	NA	NA	NA	NA
WP_000215549.1\|973865_974552_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000214712.1\|974729_974933_+	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2
WP_000527750.1\|974968_976429_-	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	5.6e-42	30.3
WP_000347482.1\|976517_977801_-	MHS family MFS transporter	NA	NA	NA	NA
WP_096846665.1\|977860_978175_+	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_122993102.1\|978545_979559_-	peptidase M85	NA	NA	NA	NA
WP_122988840.1\|979773_979851_-	hypothetical protein	NA	NA	NA	NA
WP_001023407.1\|979961_980231_-\|tail	phage tail protein	H6WZN0	Escherichia_phage	1.4e-44	98.9
WP_032325331.1\|980232_981546_-\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	1.7e-77	98.6
WP_106913818.1\|981610_982210_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	5.7e-110	98.0
WP_106913819.1\|982276_985753_-	host specificity protein J	Q687E8	Enterobacteria_phage	0.0e+00	96.1
WP_159032308.1\|985988_986621_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	2.5e-103	92.3
WP_106889273.1\|986566_987310_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	7.0e-150	98.8
WP_025404404.1\|987315_988014_-\|tail	phage minor tail protein L	S5M7Q4	Escherichia_phage	8.9e-131	97.4
WP_000807927.1\|988013_988355_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.3e-62	98.2
WP_106913813.1\|988347_991590_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	99.5
WP_001453698.1\|991641_991851_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030060.1\|991946_992321_-\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	3.0e-64	99.2
WP_001275479.1\|992326_993043_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	4.0e-126	97.5
WP_106913821.1\|993111_993747_-	DUF3168 domain-containing protein	A0A0N7KZI9	Stx2-converting_phage	3.0e-61	93.8
WP_001007911.1\|993743_994094_-\|head	phage head closure protein	H6WZL5	Escherichia_phage	2.0e-59	100.0
WP_000125984.1\|994103_994430_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	5.4e-54	100.0
WP_001063025.1\|996956_997178_-	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_096948424.1\|997222_999160_-\|capsid	phage major capsid protein	A0A0P0ZCT9	Stx2-converting_phage	0.0e+00	99.8
WP_106913822.1\|999223_1000882_-\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.1
WP_000958380.1\|1000878_1001442_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_000829192.1\|1001730_1002096_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	1.6e-62	96.7
WP_032277401.1\|1002137_1002338_+	YlcI/YnfO family protein	H6WZK6	Escherichia_phage	2.8e-29	95.5
WP_000828070.1\|1002469_1002796_-	TonB family protein	H6WZK5	Escherichia_phage	6.3e-55	98.1
WP_012817877.1\|1003196_1003382_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	4.0e-22	85.2
WP_001280923.1\|1003604_1003736_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	3.8e-11	93.0
WP_000661712.1\|1003830_1004526_-	phage antirepressor protein	Q5MBW0	Stx1-converting_phage	2.8e-124	99.1
WP_000992086.1\|1004799_1005333_-	lysozyme	B6DZ92	Enterobacteria_phage	1.3e-100	97.7
WP_032325202.1\|1005383_1005728_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	7.9e-56	96.5
WP_000284522.1\|1005732_1005948_-\|holin	holin	Q6H9V8	Enterobacteria_phage	1.3e-32	97.2
WP_000143077.1\|1006097_1007951_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.3
WP_032324351.1\|1008525_1008957_-	tellurite resistance TerB family protein	H6WZJ6	Escherichia_phage	5.6e-67	96.5
WP_000640158.1\|1009518_1010073_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	5.0e-68	69.1
WP_000247761.1\|1010069_1010360_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.3e-47	87.5
WP_000940319.1\|1010359_1010959_-	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.1e-105	92.0
WP_000138556.1\|1011458_1012850_+	ATPase	NA	NA	NA	NA
WP_000016656.1\|1012849_1013839_+	hypothetical protein	NA	NA	NA	NA
WP_001100703.1\|1013806_1014958_-	DNA cytosine methyltransferase	Q8JKX6	Natrialba_phage	1.0e-22	36.9
WP_000365100.1\|1015389_1015635_-	hypothetical protein	Q9G078	Enterobacteria_phage	5.9e-13	70.7
WP_000208018.1\|1015713_1015875_-	hypothetical protein	A0A192Y6F5	Salmonella_phage	3.2e-15	89.4
WP_000224233.1\|1015885_1016149_-	hypothetical protein	A0A2P0P958	Salmonella_phage	8.8e-31	72.4
WP_042350895.1\|1016150_1016315_-	DUF4014 family protein	A0A1I9LJM2	Stx_converting_phage	2.0e-17	90.7
WP_000935420.1\|1016400_1016613_-	hypothetical protein	A0A2R2Z310	Escherichia_phage	5.8e-33	94.3
WP_001141110.1\|1016718_1017141_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	3.1e-62	88.5
WP_000450712.1\|1017156_1017918_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	7.0e-121	90.5
WP_000788980.1\|1017940_1018687_-	ATP-binding protein	V5UQI5	Shigella_phage	5.6e-115	81.3
WP_001304174.1\|1018693_1019482_-	hypothetical protein	G9L6A8	Escherichia_phage	2.0e-41	64.3
WP_000693803.1\|1019559_1019982_-	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	1.3e-68	92.9
WP_001072342.1\|1019978_1020233_-	hypothetical protein	A0A2I6PIE5	Escherichia_phage	1.3e-18	61.6
WP_000233319.1\|1020312_1020732_+	helix-turn-helix domain-containing protein	A0A2I6PIE7	Escherichia_phage	5.5e-19	46.5
WP_001326317.1\|1020974_1021154_+	hypothetical protein	NA	NA	NA	NA
WP_001169151.1\|1021164_1021320_+	YdaF family protein	M4QQ57	Salicola_phage	6.1e-08	55.3
WP_001312793.1\|1021316_1021805_-	superinfection exclusion protein B	NA	NA	NA	NA
WP_000560223.1\|1022246_1022468_+	killing protein KilR	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
WP_001352098.1\|1022467_1022638_+	conserved protein, Rac prophage	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
WP_001344816.1\|1022712_1022988_+	hypothetical protein	A0A0U2QW85	Escherichia_phage	4.0e-42	95.6
WP_000105153.1\|1023089_1025690_+	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	6.7e-248	63.4
WP_000166313.1\|1025682_1026492_+	recombination protein RecT	A0A1P8DTF2	Proteus_phage	4.0e-106	71.5
WP_001443846.1\|1026547_1026697_+	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	2.5e-22	95.9
WP_001302840.1\|1026734_1026923_+	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	5.5e-27	98.4
WP_000079604.1\|1027022_1027238_+	excisionase XisR	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
WP_000040839.1\|1027239_1028475_+\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	3.8e-241	99.5
WP_001157407.1\|1028526_1029462_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
WP_032323876.1\|1029590_1030964_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
WP_000387388.1\|1031441_1032425_-	zinc transporter ZntB	NA	NA	NA	NA
1031659:1031674	attR	NA	NA	NA	NA
WP_000628065.1\|1032679_1033912_+	diguanylate cyclase DgcM	A0A127AWB9	Bacillus_phage	3.1e-17	39.5

DBSCAN-SWA_5

1110454 : 1248882

153

Enterobacteria_phage(26.92%)

capsid,terminase,holin,integrase,head,tail,transposase,portal,protease

attL 1148796:1148811|attR 1258140:1258155

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000422045.1\|1110454_1111504_-\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5
WP_000559281.1\|1111723_1112482_+	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	24.5
WP_001278906.1\|1112478_1113069_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_001291216.1\|1113108_1113981_-	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001342101.1\|1114081_1114702_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001285661.1\|1114698_1115580_-	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001700591.1\|1115717_1115762_+	trp operon leader peptide	NA	NA	NA	NA
WP_001194584.1\|1115853_1117416_+	anthranilate synthase component I	NA	NA	NA	NA
WP_032323871.1\|1117415_1119011_+	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
WP_001342102.1\|1119014_1120373_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	1.5e-36	40.3
WP_000209520.1\|1120384_1121578_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_000443067.1\|1121577_1122384_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000807651.1\|1122764_1122944_+	general stress protein	NA	NA	NA	NA
WP_001056491.1\|1123029_1123530_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001079509.1\|1123575_1124082_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000147167.1\|1124583_1124802_+	hypothetical protein	NA	NA	NA	NA
WP_001144877.1\|1127564_1128155_-	T3SS effector guanine nucleotide exchange factor EspM1	NA	NA	NA	NA
WP_001303944.1\|1128338_1128986_+	T3SS effector E3 ubiquitin-protein ligase NleG	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
WP_001414184.1\|1129122_1129269_-	hypothetical protein	NA	NA	NA	NA
WP_001303943.1\|1129696_1129975_+	hypothetical protein	NA	NA	NA	NA
WP_000938103.1\|1131142_1131712_-	T3SS effector caspase inhibitor NleF	NA	NA	NA	NA
WP_000950979.1\|1131777_1132689_-	type III secretion system effector kinase NleH1-2	A5LH48	Enterobacteria_phage	3.0e-134	82.2
WP_106409364.1\|1132795_1132918_-	hypothetical protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
WP_001023357.1\|1136863_1137133_-\|tail	phage tail protein	A0A2R2Z347	Escherichia_phage	3.8e-45	100.0
WP_001339397.1\|1137193_1137871_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|1137870_1138218_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381395.1\|1138237_1139809_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000216552.1\|1139841_1141155_-\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	6.9e-76	98.4
WP_001228278.1\|1141306_1141906_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	5.9e-107	95.5
WP_000902073.1\|1141973_1143023_-	DUF1983 domain-containing protein	Q9EYE7	Enterobacteria_phage	4.5e-195	100.0
WP_000099160.1\|1143045_1144584_-\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_000612626.1\|1144632_1144980_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839179.1\|1144976_1145381_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_106913823.1\|1145458_1147909_-	host specificity protein J	A0A0P0ZEQ8	Stx2-converting_phage	0.0e+00	96.0
WP_159032308.1\|1148144_1148777_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	2.5e-103	92.3
WP_106889273.1\|1148722_1149466_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	7.0e-150	98.8
1148796:1148811	attL	NA	NA	NA	NA
WP_025404404.1\|1149471_1150170_-\|tail	phage minor tail protein L	S5M7Q4	Escherichia_phage	8.9e-131	97.4
WP_000807956.1\|1150169_1150511_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	1.5e-62	99.1
WP_106913824.1\|1150503_1153746_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	94.1
WP_001453698.1\|1153797_1154007_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030063.1\|1154102_1154477_-\|tail	tail assembly protein	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_032325206.1\|1154482_1155199_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	8.0e-127	98.7
WP_000133388.1\|1155264_1155609_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_106881388.1\|1155605_1156052_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	1.2e-75	99.3
WP_001007905.1\|1156048_1156399_-\|head	phage head closure protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
WP_032325002.1\|1156409_1156736_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDE0	Stx2-converting_phage	1.2e-53	99.1
WP_001063099.1\|1159262_1159484_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_032325321.1\|1159528_1161307_-\|capsid	phage major capsid protein	A0A0P0ZCT9	Stx2-converting_phage	0.0e+00	90.1
WP_106889267.1\|1161370_1163032_-\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.3
WP_000958380.1\|1163028_1163592_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_000279801.1\|1163883_1164249_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	2.3e-61	95.9
WP_000095732.1\|1164290_1164491_+	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	3.7e-29	95.5
WP_000828072.1\|1164622_1164949_-	TonB family protein	H6WZK5	Escherichia_phage	3.4e-56	98.1
WP_001109019.1\|1165294_1165846_-	Rha family transcriptional regulator	A0A0P0ZFJ1	Escherichia_phage	4.5e-101	100.0
WP_071529499.1\|1166084_1166270_-	hypothetical protein	A0A0P0ZCT3	Stx2-converting_phage	1.3e-17	96.7
WP_001280922.1\|1166492_1166624_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	8.5e-11	90.7
WP_000661712.1\|1166718_1167414_-	phage antirepressor protein	Q5MBW0	Stx1-converting_phage	2.8e-124	99.1
WP_000087733.1\|1167687_1168221_-	lysozyme	G9L6J6	Escherichia_phage	1.0e-102	100.0
WP_001072901.1\|1168225_1168441_-\|holin	holin	A0A2R2Z340	Escherichia_phage	1.2e-33	100.0
WP_001290230.1\|1168518_1168764_-	DUF826 domain-containing protein	A0A0P0ZGR2	Escherichia_phage	8.8e-17	100.0
WP_000143463.1\|1168804_1168984_-	DUF1378 family protein	Q5MBW3	Stx1-converting_phage	4.4e-26	100.0
WP_106889297.1\|1169119_1171057_-	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	0.0e+00	99.2
WP_000752026.1\|1171556_1171826_-	Shiga toxin Stx1a subunit B	Q7AYI7	Enterobacteria_phage	1.6e-43	100.0
WP_000691354.1\|1171835_1172783_-	Shiga toxin Stx1 subunit A	Q777W4	Enterobacteria_phage	3.2e-171	100.0
WP_032324021.1\|1173289_1173724_-	antitermination protein	Q5MBW8	Stx1-converting_phage	4.8e-82	100.0
WP_000144759.1\|1173716_1173911_-	protein ninH	Q6H9W6	Enterobacteria_phage	8.4e-31	100.0
WP_085948186.1\|1173987_1175143_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_001303849.1\|1175417_1175636_+	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000533665.1\|1175613_1176687_+\|integrase	tyrosine-type recombinase/integrase	Q9G075	Enterobacteria_phage	2.0e-198	98.9
WP_001444338.1\|1176781_1179526_+	TMAO reductase system sensor histidine kinase/response regulator TorS	A0A1V0SGX0	Hokovirus	1.0e-36	31.9
WP_000818472.1\|1179597_1180671_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_001019197.1\|1180718_1180892_-	addiction module toxin, GnsA/GnsB family	NA	NA	NA	NA
WP_001316982.1\|1180881_1181112_-	protein YmcE	NA	NA	NA	NA
WP_071524879.1\|1181086_1181275_-	cold-shock protein	NA	NA	NA	NA
WP_000066490.1\|1181285_1181498_-	cold shock protein CspG	A0A1W6JNX5	Morganella_phage	7.8e-22	71.4
WP_000087763.1\|1181783_1181996_+	cold shock-like protein CspH	NA	NA	NA	NA
WP_001295358.1\|1182437_1182743_+	threonine-rich inner membrane protein GfcA	NA	NA	NA	NA
WP_001247610.1\|1182849_1183494_+	lipoprotein GfcB	NA	NA	NA	NA
WP_001038062.1\|1183490_1184237_+	capsule biosynthesis GfcC family protein	NA	NA	NA	NA
WP_000742345.1\|1184236_1186333_+	YjbH domain-containing protein	NA	NA	NA	NA
WP_001295357.1\|1186378_1187518_+	polysaccharide export protein	NA	NA	NA	NA
WP_000057871.1\|1187505_1187952_+	protein-tyrosine-phosphatase Etp	NA	NA	NA	NA
WP_000208650.1\|1187971_1190152_+	tyrosine-protein kinase	NA	NA	NA	NA
WP_001300464.1\|1190266_1191565_-	AppA family phytase/histidine-type acid phosphatase	NA	NA	NA	NA
WP_000270305.1\|1191644_1191737_-	cytochrome bd-II oxidase subunit CbdX	NA	NA	NA	NA
WP_000460810.1\|1191749_1192886_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_071527988.1\|1192897_1194394_-	cytochrome bd-II oxidase subunit 1	NA	NA	NA	NA
WP_000004899.1\|1194576_1195434_-	hydrogenase expression/formation protein	NA	NA	NA	NA
WP_000063972.1\|1195430_1195829_-	hydrogenase-1 operon protein HyaE	NA	NA	NA	NA
WP_000003671.1\|1195825_1196413_-\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA
WP_001186421.1\|1196409_1197117_-	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_000107384.1\|1197135_1198929_-	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_001058323.1\|1198925_1200044_-	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_095585410.1\|1200639_1200792_-\|tail	phage tail protein	K7PMH7	Enterobacteria_phage	4.3e-14	84.4
WP_000938124.1\|1201168_1202530_+	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	1.5e-49	40.2
WP_001023483.1\|1202984_1203254_-\|tail	phage tail protein	Q687E5	Enterobacteria_phage	1.2e-43	96.6
WP_000381395.1\|1203291_1204863_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|1204882_1205230_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|1205229_1205907_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_032325383.1\|1205962_1207276_-\|tail	tail fiber protein	H6WZM9	Escherichia_phage	2.2e-77	98.2
WP_001230428.1\|1207340_1207940_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	1.4e-111	99.5
WP_106913825.1\|1208006_1211480_-	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	98.1
WP_123010699.1\|1211725_1212358_-\|tail	tail assembly protein	A0A0N7KZG2	Stx2-converting_phage	1.6e-94	95.7
WP_000194707.1\|1212303_1213047_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	1.2e-149	99.2
WP_001443841.1\|1213057_1213756_-\|tail	phage minor tail protein L	Q687F1	Enterobacteria_phage	4.4e-130	97.4
WP_000847298.1\|1213755_1214085_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_106913826.1\|1214081_1216694_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	94.3
WP_000533442.1\|1216674_1217088_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_000479051.1\|1217114_1217537_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	2.4e-70	97.9
WP_000235067.1\|1217550_1218303_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.2e-133	98.4
WP_000683137.1\|1218310_1218706_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	3.7e-65	92.4
WP_000975098.1\|1218702_1219281_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.0e-79	98.4
WP_000752994.1\|1219292_1219646_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.0e-63	100.0
WP_022581670.1\|1219657_1220053_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	5.3e-56	93.2
WP_000063258.1\|1220094_1221120_-\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	5.1e-191	98.8
WP_001365129.1\|1221175_1221508_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.5e-54	98.2
WP_000123292.1\|1221517_1222837_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.5e-232	98.2
WP_001443752.1\|1222817_1224419_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	3.6e-308	98.7
WP_000198153.1\|1224415_1224622_-\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_000453587.1\|1226518_1227064_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_044705177.1\|1227452_1227677_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.8e-20	92.5
WP_001302717.1\|1227758_1228073_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001208680.1\|1228598_1228784_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_000539795.1\|1229006_1229153_-	hypothetical protein	A0A0P0ZG36	Escherichia_phage	1.1e-11	87.0
WP_001056806.1\|1229152_1229722_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_085948186.1\|1229858_1231014_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_106913827.1\|1231011_1231698_-	antitermination protein	Q8SBE4	Shigella_phage	1.3e-113	98.6
WP_001375683.1\|1231711_1232761_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.6e-115	57.6
WP_012817785.1\|1232762_1233032_-	hypothetical protein	I6PCV7	Cronobacter_phage	3.0e-10	49.2
WP_001452497.1\|1233085_1233313_-	hypothetical protein	NA	NA	NA	NA
WP_032325073.1\|1233536_1233908_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000042395.1\|1233900_1234218_+	DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000882662.1\|1234320_1234533_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	2.5e-28	95.7
WP_000211993.1\|1234747_1235299_-	ORF6N domain-containing protein	A0A0N7C203	Escherichia_phage	5.5e-43	53.3
WP_000215512.1\|1235650_1235836_-	hypothetical protein	NA	NA	NA	NA
WP_000450895.1\|1235895_1236657_-	DUF1627 domain-containing protein	A0A088CE47	Shigella_phage	2.4e-73	63.6
WP_000790460.1\|1236686_1237427_-	ATP-binding protein	A0A088CBP4	Shigella_phage	4.7e-114	83.1
WP_000054520.1\|1237433_1238399_-	hypothetical protein	U5P0A0	Shigella_phage	5.0e-55	61.2
WP_000705368.1\|1238379_1238901_-	hypothetical protein	NA	NA	NA	NA
WP_000920571.1\|1238884_1239115_-	dicB transcriptional regulator DicC	NA	NA	NA	NA
WP_000379972.1\|1239198_1239606_+	helix-turn-helix domain-containing protein	B1B6L9	Salmonella_phage	3.1e-14	58.7
WP_000380319.1\|1239772_1239925_+	DUF1391 family protein	M4QQ57	Salicola_phage	6.6e-07	53.2
WP_000394548.1\|1239936_1240575_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_001133037.1\|1240575_1240785_-	hypothetical protein	NA	NA	NA	NA
WP_000449175.1\|1241349_1241538_+	cell division inhibitor	NA	NA	NA	NA
WP_000199475.1\|1241534_1241723_+	DUF1482 family protein	NA	NA	NA	NA
WP_000102128.1\|1241815_1244278_+	exonuclease	V5UQJ3	Shigella_phage	2.3e-125	47.5
WP_001368608.1\|1244365_1244602_+	excisionase family protein	S4TND0	Salmonella_phage	6.1e-15	50.7
WP_001206148.1\|1244621_1245917_+\|integrase	site-specific integrase	B6DZ48	Enterobacteria_phage	2.5e-155	62.3
WP_072095801.1\|1245936_1246047_-	transporter	NA	NA	NA	NA
WP_000836079.1\|1246104_1247124_-	Zn-dependent oxidoreductase	E3SJ82	Synechococcus_phage	9.7e-17	25.9
WP_001295394.1\|1247135_1248350_-	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	1.4e-46	29.0
WP_000598292.1\|1248555_1248882_-	YnfA family protein	A0A218MNG8	uncultured_virus	9.9e-24	55.6
1258140:1258155	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1265167 : 1283218

uncultured_Caudovirales_phage(83.33%)

capsid,terminase,integrase,head,transposase,portal,protease

attL 1270792:1270807|attR 1294398:1294413

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001260840.1\|1265167_1265989_+\|protease	serine protease	NA	NA	NA	NA
WP_000046661.1\|1266027_1266357_-	multidrug/spermidine efflux SMR transporter subunit MdtI	NA	NA	NA	NA
WP_000276149.1\|1266343_1266709_-	multidrug/spermidine efflux SMR transporter subunit MdtJ	NA	NA	NA	NA
WP_001303517.1\|1266815_1266986_-	hypothetical protein	NA	NA	NA	NA
WP_000133423.1\|1268022_1268304_-	hypothetical protein	NA	NA	NA	NA
WP_000127891.1\|1268317_1269979_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	2.0e-277	81.6
WP_000113645.1\|1269962_1270319_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	9.4e-52	81.4
WP_001145905.1\|1270608_1271049_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	2.5e-62	72.6
1270792:1270807	attL	NA	NA	NA	NA
WP_000134113.1\|1271048_1271345_-	hypothetical protein	A0A2H4JD08	uncultured_Caudovirales_phage	4.0e-32	65.3
WP_001020674.1\|1271341_1271680_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	8.7e-31	52.7
WP_001398592.1\|1271676_1272852_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	4.8e-185	80.2
WP_000504055.1\|1272889_1273462_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	4.7e-61	63.0
WP_001137345.1\|1273501_1274659_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	2.8e-137	64.9
WP_085948186.1\|1275064_1276221_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_159026385.1\|1276277_1276442_-	hypothetical protein	NA	NA	NA	NA
WP_000233310.1\|1276567_1276840_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_000126691.1\|1276850_1277261_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_000125509.1\|1277257_1277503_-	hypothetical protein	NA	NA	NA	NA
WP_000710169.1\|1277790_1279608_-	DNA primase	Q7M2A8	Enterobacteria_phage	7.5e-129	48.3
WP_001261490.1\|1279604_1279904_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_001113154.1\|1279910_1280231_-	hypothetical protein	NA	NA	NA	NA
WP_024184083.1\|1280223_1280514_-	host cell division inhibitor Icd-like protein	NA	NA	NA	NA
WP_001496008.1\|1280446_1281373_-	hypothetical protein	NA	NA	NA	NA
WP_000953271.1\|1281425_1281614_-	AlpA family transcriptional regulator	A0A2H4JB58	uncultured_Caudovirales_phage	5.9e-13	64.2
WP_000085277.1\|1281988_1283218_-\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.6e-130	55.4
1294398:1294413	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1479651 : 1574250

107

Escherichia_phage(36.51%)

lysis,capsid,tRNA,holin,integrase,head,tail,transposase,portal,protease

attL 1519157:1519171|attR 1575697:1575711

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071830504.1\|1479651_1480860_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	1.7e-206	92.5
WP_000604932.1\|1480867_1481299_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	4.8e-42	58.4
WP_000513743.1\|1481314_1481503_-	DUF1869 domain-containing protein	NA	NA	NA	NA
WP_000939317.1\|1481506_1481866_-	DUF1971 domain-containing protein	NA	NA	NA	NA
WP_000457202.1\|1482038_1482677_-	leucine efflux protein LeuE	NA	NA	NA	NA
WP_001061578.1\|1482803_1483727_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000978494.1\|1483829_1484915_+	multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase	NA	NA	NA	NA
WP_000987525.1\|1485165_1486776_+	BCCT family transporter YeaV	NA	NA	NA	NA
WP_000067805.1\|1486807_1487932_+	carnitine monooxygenase subunit YeaW	NA	NA	NA	NA
WP_001287005.1\|1487987_1488953_+	carnitine monooxygenase subunit YeaX	NA	NA	NA	NA
WP_001342154.1\|1489006_1490122_-	ribonuclease D	NA	NA	NA	NA
WP_000758422.1\|1490203_1491889_-	long-chain-fatty-acid--CoA ligase FadD	A0A2H4PQM9	Staphylococcus_phage	1.5e-35	26.0
WP_000290576.1\|1492093_1492675_-	Slp family lipoprotein YeaY	NA	NA	NA	NA
WP_001221003.1\|1492714_1493410_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_000128847.1\|1493467_1495378_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	4.5e-92	31.9
WP_001295493.1\|1495509_1495854_+	RidA family protein	NA	NA	NA	NA
WP_001307845.1\|1496216_1496576_+	DUF1889 family protein	NA	NA	NA	NA
WP_000457334.1\|1496695_1496875_-	YoaH family protein	NA	NA	NA	NA
WP_000854972.1\|1496948_1498310_+	aminodeoxychorismate synthase component 1	S4VT78	Pandoravirus	3.4e-41	33.4
WP_000456725.1\|1498313_1498892_+	CoA pyrophosphatase	NA	NA	NA	NA
WP_032324016.1\|1499075_1500440_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_001295494.1\|1500570_1502169_+	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
WP_000150551.1\|1504190_1505162_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_000406926.1\|1505224_1506025_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_000228655.1\|1506037_1506889_+	PTS mannose transporter subunit IID	NA	NA	NA	NA
WP_000156255.1\|1506943_1507402_+	DUF986 domain-containing protein	NA	NA	NA	NA
WP_001296134.1\|1507830_1508397_+	manganese efflux pump MntP	NA	NA	NA	NA
WP_000010107.1\|1508393_1509203_-	23S rRNA (guanine(745)-N(1))-methyltransferase	NA	NA	NA	NA
WP_001062678.1\|1509368_1509578_-	transcription antiterminator/RNA stability regulator CspE	A0A1W6JNX5	Morganella_phage	1.6e-22	78.1
WP_001295496.1\|1509590_1509734_-	YobF family protein	NA	NA	NA	NA
WP_001006866.1\|1510402_1510690_-	hypothetical protein	NA	NA	NA	NA
WP_000714550.1\|1510764_1510908_-	PhoP/PhoQ regulator MgrB	NA	NA	NA	NA
WP_001211011.1\|1511066_1511306_+	hypothetical protein	NA	NA	NA	NA
WP_001262174.1\|1511448_1512240_-	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
WP_001127210.1\|1512416_1513790_+	MFS transporter	NA	NA	NA	NA
WP_000984517.1\|1513835_1514717_-\|protease	protease HtpX	NA	NA	NA	NA
WP_001427396.1\|1514908_1516957_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	6.8e-86	33.5
WP_000431370.1\|1516976_1517675_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_001043882.1\|1517771_1518269_-	GAF domain-containing protein	NA	NA	NA	NA
WP_001207284.1\|1518398_1519682_+	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
1519157:1519171	attL	NA	NA	NA	NA
WP_001299674.1\|1519650_1522284_+	lipid-binding membrane homeostasis protein YebT	NA	NA	NA	NA
WP_000057024.1\|1522363_1523803_+	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_001295499.1\|1523920_1524157_+	DUF1480 family protein	NA	NA	NA	NA
WP_001296140.1\|1524261_1524453_+	YebW family protein	NA	NA	NA	NA
WP_000812724.1\|1524453_1525110_-	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	3.1e-56	50.2
WP_001121225.1\|1526064_1526715_+	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_000491545.1\|1526939_1527815_-	hypothetical protein	A0A0P0ZCT1	Stx2-converting_phage	7.2e-162	99.7
WP_001023379.1\|1527955_1528225_-\|tail	phage tail protein	Q687E5	Enterobacteria_phage	8.7e-42	95.5
WP_106875077.1\|1528226_1529540_-\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	2.8e-77	97.3
WP_044722165.1\|1529604_1530204_-	Ail/Lom family outer membrane beta-barrel protein	Q687E7	Enterobacteria_phage	5.2e-111	99.0
WP_106913828.1\|1530271_1533664_-	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	84.6
WP_136865658.1\|1533899_1534532_-\|tail	tail assembly protein	Q9EYE5	Enterobacteria_phage	4.6e-102	91.8
WP_032325227.1\|1534477_1535221_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	4.5e-149	99.2
WP_001152185.1\|1535231_1535930_-\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	3.1e-131	98.7
WP_000847302.1\|1535929_1536259_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	1.2e-53	94.5
WP_106889282.1\|1536255_1538835_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	83.1
WP_000533431.1\|1538815_1539229_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.0e-41	82.8
WP_000479086.1\|1539255_1539687_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	4.8e-42	68.1
WP_032325228.1\|1539700_1540453_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.3e-130	95.6
WP_000683137.1\|1540460_1540856_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	3.7e-65	92.4
WP_000975096.1\|1540852_1541431_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000752994.1\|1541442_1541796_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	9.0e-63	100.0
WP_000158897.1\|1541807_1542203_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	2.4e-56	93.9
WP_000063258.1\|1542244_1543270_-\|capsid	major capsid protein	A0A2I6TCE5	Escherichia_phage	5.1e-191	98.8
WP_001365129.1\|1543325_1543658_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.5e-54	98.2
WP_000123251.1\|1543667_1544987_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	7.6e-232	97.9
WP_001443752.1\|1544967_1546569_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	3.6e-308	98.7
WP_000198153.1\|1546565_1546772_-\|head,tail	head-tail joining protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_000453587.1\|1548668_1549214_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	1.4e-94	98.9
WP_001307652.1\|1549602_1549797_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	9.7e-27	96.8
WP_000881326.1\|1549984_1550602_-	hypothetical protein	A0A1R3Y613	Salmonella_virus	6.5e-93	85.9
WP_000092325.1\|1550751_1551189_-\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	1.7e-71	98.6
WP_000075132.1\|1551185_1551683_-	lysozyme	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_000411802.1\|1551682_1551889_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	2.4e-31	100.0
WP_000143049.1\|1552336_1554187_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	99.2
WP_000762928.1\|1555357_1556179_-	antitermination protein	K7P7B9	Enterobacteria_phage	4.1e-82	61.2
WP_001217413.1\|1556175_1556550_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.4e-34	63.6
WP_001265229.1\|1556562_1557612_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.6
WP_000191872.1\|1557613_1557886_-	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_000756596.1\|1558007_1558352_-	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_000935259.1\|1558471_1558684_-	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_000104474.1\|1558917_1559475_-	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
WP_000683609.1\|1559476_1559695_-	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	2.3e-21	72.2
WP_001289673.1\|1559822_1560134_-	hypothetical protein	A0A0U2QV73	Escherichia_phage	7.2e-56	92.2
WP_000699809.1\|1560126_1560354_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
WP_000603384.1\|1560350_1560632_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
WP_000450872.1\|1560664_1561426_-	DUF1627 domain-containing protein	A0A088CE47	Shigella_phage	3.9e-79	67.2
WP_001444941.1\|1562199_1563162_-	DNA-binding protein	U5P0A0	Shigella_phage	2.7e-69	51.5
WP_000693943.1\|1563184_1563610_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000172738.1\|1563606_1563909_-	transcriptional regulator	K7PHA1	Enterobacteria_phage	8.6e-06	34.8
WP_001169687.1\|1564006_1564378_+	hypothetical protein	NA	NA	NA	NA
WP_001302048.1\|1564398_1564590_+	hypothetical protein	NA	NA	NA	NA
WP_001303511.1\|1564591_1564870_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_001427316.1\|1565156_1565309_+	DUF1391 family protein	M4QQ57	Salicola_phage	2.3e-07	55.3
WP_000560218.1\|1565729_1565951_+	killing protein KilR	A0A0U2RTC4	Escherichia_phage	1.8e-37	98.6
WP_001427414.1\|1565950_1566121_+	hypothetical protein	A0A0U2SHB5	Escherichia_phage	3.3e-23	89.3
WP_001307773.1\|1566194_1566470_+	hypothetical protein	A0A0U2QW85	Escherichia_phage	3.0e-42	96.7
WP_000105101.1\|1566568_1569220_+	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	0.0e+00	77.6
WP_000166317.1\|1569212_1570022_+	recombination protein RecT	A0A1P8DTF2	Proteus_phage	6.8e-106	71.5
WP_042853000.1\|1570078_1570273_+	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	A0A0U2QQP4	Escherichia_phage	7.6e-32	96.9
WP_001356607.1\|1570265_1570454_+	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	1.6e-18	97.9
WP_001443927.1\|1570560_1570842_+	excisionase	A0A2H4J5E1	uncultured_Caudovirales_phage	1.7e-11	41.2
WP_001189091.1\|1570807_1571884_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	5.3e-98	51.7
WP_000976492.1\|1572276_1572618_-	YebY family protein	NA	NA	NA	NA
WP_000879280.1\|1572630_1573503_-	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_000204699.1\|1573506_1573881_-	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_000916763.1\|1574019_1574250_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	1.3e-14	61.8
1575697:1575711	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1620523 : 1694444

Enterobacteria_phage(75.0%)

capsid,tRNA,terminase,holin,head,tail,plate,integrase,portal

attL 1658058:1658117|attR 1695387:1695507

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000564746.1\|1620523_1621495_+\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_032323745.1\|1621659_1624089_-	trimethylamine N-oxide reductase TorZ	NA	NA	NA	NA
WP_001214304.1\|1624113_1625214_-	cytochrome c	NA	NA	NA	NA
WP_032323742.1\|1625601_1626348_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_001300190.1\|1626361_1626928_-	VOC family protein	NA	NA	NA	NA
WP_001025336.1\|1627143_1628877_+\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	6.8e-87	33.7
WP_001297434.1\|1629053_1629542_+	lysozyme inhibitor LprI family protein	NA	NA	NA	NA
WP_001259583.1\|1629661_1630054_-	flagellar protein FlhE	NA	NA	NA	NA
WP_000067000.1\|1630053_1632132_-	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_106889285.1\|1632124_1633273_-	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_000983609.1\|1633474_1634119_-	protein phosphatase CheZ	NA	NA	NA	NA
WP_000763867.1\|1634129_1634519_-	chemotaxis protein CheY	A0A2K9L4R0	Tupanvirus	1.3e-06	32.0
WP_000036378.1\|1634533_1635583_-	chemotaxis response regulator protein-glutamate methylesterase	Q56AR1	Bacillus_thuringiensis_phage	1.0e-05	32.8
WP_000204335.1\|1635585_1636446_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_000483235.1\|1636464_1638069_-	methyl-accepting chemotaxis protein IV	A0A2H4J162	uncultured_Caudovirales_phage	1.2e-13	29.6
WP_001342228.1\|1638114_1639776_-	methyl-accepting chemotaxis protein II	A0A2H4J162	uncultured_Caudovirales_phage	1.7e-10	40.3
WP_000147302.1\|1639920_1640424_-	chemotaxis protein CheW	NA	NA	NA	NA
WP_001300654.1\|1640444_1642409_-	chemotaxis protein CheA	NA	NA	NA	NA
WP_000795630.1\|1642413_1643340_-	flagellar motor protein MotB	NA	NA	NA	NA
WP_000906335.1\|1643336_1644224_-	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_001291603.1\|1644350_1644929_-	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_001295647.1\|1644931_1645282_-	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_000122426.1\|1646061_1646490_+	universal stress protein UspC	NA	NA	NA	NA
WP_001295646.1\|1646496_1647921_-	alpha,alpha-trehalose-phosphate synthase	NA	NA	NA	NA
WP_001295645.1\|1647895_1648696_-	trehalose-phosphatase	NA	NA	NA	NA
WP_000100203.1\|1648862_1649849_-	L-arabinose ABC transporter permease AraH	NA	NA	NA	NA
WP_001187810.1\|1649863_1651378_-	L-arabinose ABC transporter ATP-binding protein AraG	A0A2H4PQG7	Staphylococcus_phage	4.3e-13	27.1
WP_000548675.1\|1651447_1652437_-	arabinose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000179469.1\|1653233_1653737_+	non-heme ferritin-like protein	NA	NA	NA	NA
WP_000082123.1\|1653815_1654067_-	DUF2766 domain-containing protein	NA	NA	NA	NA
WP_010723106.1\|1654181_1654268_-	stress response protein AzuC	NA	NA	NA	NA
WP_001237869.1\|1654530_1654854_+	lipoprotein, function unknown	NA	NA	NA	NA
WP_000917208.1\|1655024_1655522_+	non-heme ferritin	NA	NA	NA	NA
WP_000377224.1\|1655559_1655799_-	YecH family protein	NA	NA	NA	NA
WP_000797573.1\|1655989_1657201_+	tyrosine transporter TyrP	NA	NA	NA	NA
WP_000847902.1\|1657262_1657928_-	UPF0149 family protein YecA	NA	NA	NA	NA
1658058:1658117	attL	NA	NA	NA	NA
WP_001342226.1\|1658284_1659286_-\|integrase	tyrosine-type recombinase/integrase	Q94N03	Haemophilus_virus	9.3e-105	58.2
WP_000865208.1\|1659291_1659639_-	DUF2511 domain-containing protein	NA	NA	NA	NA
WP_000290352.1\|1659668_1660319_-	membrane protein	NA	NA	NA	NA
WP_000786769.1\|1660334_1660739_-	transcriptional regulator	Q6QID2	Burkholderia_phage	1.6e-23	53.8
WP_001673482.1\|1660828_1660966_-	hypothetical protein	NA	NA	NA	NA
WP_000014504.1\|1661037_1661241_+	DNA-binding protein	P79674	Haemophilus_phage	3.1e-07	45.2
WP_000742491.1\|1661262_1661613_+	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	1.2e-48	81.0
WP_000158976.1\|1661623_1661902_+	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	6.9e-34	77.2
WP_000357025.1\|1661913_1662156_+	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	3.4e-37	97.5
WP_032323740.1\|1662152_1662266_+	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	5.2e-09	89.2
WP_000985152.1\|1662352_1662556_+	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	9.5e-25	80.6
WP_000564224.1\|1662879_1663269_+	hypothetical protein	NA	NA	NA	NA
WP_001272083.1\|1663265_1666106_+	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	88.6
WP_000686499.1\|1666182_1667142_+	recombinase	A0A0A7NPX4	Enterobacteria_phage	2.0e-181	99.7
WP_000211289.1\|1667146_1667458_+	chromosome partitioning protein	A0A0A7NPT5	Enterobacteria_phage	1.2e-47	95.1
WP_001289969.1\|1667521_1668112_+	ead/Ea22-like family protein	Q8HAA6	Salmonella_phage	1.8e-31	50.7
WP_000087812.1\|1668601_1669648_-\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.5e-206	100.0
WP_000613774.1\|1669647_1671399_-\|terminase	terminase	A0A0A7NV54	Enterobacteria_phage	0.0e+00	98.1
WP_001262641.1\|1671553_1672390_+\|capsid	phage capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	7.9e-150	98.9
WP_001055094.1\|1672413_1673466_+\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	3.2e-188	94.3
WP_000632311.1\|1673511_1674312_+\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	1.5e-126	89.1
WP_000063100.1\|1674413_1674908_+\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	1.9e-87	97.0
WP_106913831.1\|1674907_1675162_+\|tail	phage tail protein	A0A0A7NV57	Enterobacteria_phage	2.9e-31	98.5
WP_001342221.1\|1675109_1675433_+\|holin	holin	A0A0A7NRY9	Enterobacteria_phage	1.7e-47	93.5
WP_000072343.1\|1675429_1675822_+	M15 family metallopeptidase	A0A0A7NQ86	Enterobacteria_phage	2.9e-70	98.5
WP_000780555.1\|1675818_1676226_+	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	4.2e-64	95.6
WP_000202151.1\|1676364_1678242_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	1.1e-305	82.2
WP_001342220.1\|1678265_1678733_+\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	6.7e-82	94.8
WP_032324046.1\|1678725_1679361_+	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	3.1e-114	99.5
WP_001271909.1\|1679357_1679939_+\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	1.2e-101	97.4
WP_000213447.1\|1679935_1680286_+\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	9.2e-60	100.0
WP_001111967.1\|1680289_1681186_+\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	1.9e-154	97.7
WP_000071738.1\|1681178_1681709_+\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	4.3e-93	98.8
WP_000108514.1\|1681711_1683844_+\|tail	phage tail protein	U5N099	Enterobacteria_phage	8.0e-130	66.2
WP_000144010.1\|1683843_1684422_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.2e-95	88.5
WP_000954196.1\|1684465_1685038_-	serine acetyltransferase	NA	NA	NA	NA
WP_000979950.1\|1685194_1685683_-\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	7.5e-84	98.1
WP_000763327.1\|1688488_1688617_-\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	3.0e-16	97.6
WP_000665308.1\|1688652_1689018_-\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	3.8e-56	97.5
WP_000290450.1\|1689072_1689585_-\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	3.2e-93	100.0
WP_000005439.1\|1689584_1690769_-\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	3.4e-223	98.5
WP_000132847.1\|1690926_1692027_+	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	2.1e-203	98.6
WP_001317900.1\|1692426_1693566_+	SEC-C domain-containing protein	NA	NA	NA	NA
WP_000488107.1\|1693852_1694113_+	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_000078921.1\|1694303_1694444_+	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	5.9e-18	97.8
1695387:1695507	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1843495 : 1853404

Enterobacteria_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001484691.1\|1843495_1844602_-	DegT/DnrJ/EryC1/StrS family aminotransferase	E5ES42	Bathycoccus_sp._RCC1105_virus	5.2e-40	31.0
WP_024168774.1\|1844621_1845017_-	WxcM-like domain-containing protein	NA	NA	NA	NA
WP_016247326.1\|1845012_1845561_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A218MN57	uncultured_virus	4.2e-43	48.4
WP_001484692.1\|1845598_1846408_-	glycosyltransferase	NA	NA	NA	NA
WP_001383307.1\|1846434_1847307_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.8e-105	63.1
WP_016247327.1\|1847364_1848264_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	4.4e-29	34.8
WP_001383310.1\|1848263_1849349_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.8e-101	54.2
WP_000183060.1\|1849720_1850614_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_000999466.1\|1850856_1851852_-	SDR family oxidoreductase	A0A1V0QG29	Shearwaterpox_virus	1.9e-09	26.3
WP_016247328.1\|1852009_1853404_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	8.3e-19	31.9

DBSCAN-SWA_10

1945161 : 1955089

Enterobacteria_phage(62.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001292774.1\|1945161_1946298_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7
WP_001342301.1\|1946294_1948295_+	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.0
WP_001171523.1\|1948626_1949007_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_000612591.1\|1949003_1949351_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998019.1\|1949400_1950786_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.4e-259	89.3
WP_000950404.1\|1951217_1951688_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	2.0e-81	99.4
WP_000598641.1\|1951734_1952454_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295431.1\|1952450_1954136_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_001240401.1\|1954357_1955089_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5

DBSCAN-SWA_11

2025913 : 2128063

117

Enterobacteria_phage(37.5%)

lysis,integrase,terminase,holin,head,tail,transposase,portal,protease

attL 2063062:2063080|attR 2137278:2137296

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000101718.1\|2025913_2027155_+\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	1.2e-98	43.1
WP_000387479.1\|2027651_2027858_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_001443784.1\|2028541_2029102_+	host cell division inhibitor Icd-like protein	Q8SBF3	Shigella_phage	9.0e-17	45.5
WP_001372127.1\|2029091_2029313_+	hypothetical protein	NA	NA	NA	NA
WP_001204070.1\|2029305_2029527_+	hypothetical protein	NA	NA	NA	NA
WP_001204970.1\|2029528_2029762_+	hypothetical protein	NA	NA	NA	NA
WP_000770163.1\|2029767_2030067_+	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_000833625.1\|2030063_2031464_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.6e-115	60.1
WP_001080641.1\|2031665_2031911_+	hypothetical protein	NA	NA	NA	NA
WP_000391151.1\|2032041_2032236_+	hypothetical protein	NA	NA	NA	NA
WP_001018604.1\|2032239_2032401_+	hypothetical protein	NA	NA	NA	NA
WP_001229487.1\|2032528_2033017_+\|terminase	terminase small subunit	A0A0P0ZCQ9	Stx2-converting_phage	4.6e-25	42.3
WP_000624042.1\|2033179_2034103_+	hypothetical protein	A0A0R6PHC6	Moraxella_phage	6.9e-14	24.9
WP_001113637.1\|2037481_2038129_+	nitrate/nitrite response regulator protein NarP	NA	NA	NA	NA
WP_001211567.1\|2038163_2039216_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_106889291.1\|2039212_2039770_-	thiol:disulfide interchange protein DsbE	NA	NA	NA	NA
WP_000982426.1\|2039766_2041710_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_001026418.1\|2041706_2042186_-	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_000186540.1\|2042182_2042392_-	heme exporter protein CcmD	NA	NA	NA	NA
WP_001295447.1\|2042388_2043126_-	heme exporter protein CcmC	NA	NA	NA	NA
WP_000971723.1\|2043167_2043830_-	heme exporter protein CcmB	NA	NA	NA	NA
WP_000888560.1\|2043826_2044444_-	cytochrome c biogenesis heme-transporting ATPase CcmA	G3M9Y6	Bacillus_virus	1.9e-12	25.5
WP_000528376.1\|2044462_2045065_-	cytochrome c-type protein NapC	NA	NA	NA	NA
WP_000835177.1\|2045074_2045524_-	nitrate reductase cytochrome c-type subunit	NA	NA	NA	NA
WP_000013509.1\|2045520_2046384_-	quinol dehydrogenase ferredoxin subunit NapH	NA	NA	NA	NA
WP_000091291.1\|2046370_2047066_-	ferredoxin-type protein NapG	NA	NA	NA	NA
WP_000778069.1\|2047072_2049559_-	nitrate reductase catalytic subunit NapA	NA	NA	NA	NA
WP_000557378.1\|2049555_2049819_-	chaperone NapD	NA	NA	NA	NA
WP_000686723.1\|2049808_2050303_-	ferredoxin-type protein NapF	NA	NA	NA	NA
WP_001296837.1\|2050411_2050576_+	hypothetical protein	NA	NA	NA	NA
WP_000849214.1\|2050711_2051200_+\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_000758074.1\|2051348_2052995_-	malate dehydrogenase (quinone)	NA	NA	NA	NA
WP_000422231.1\|2053212_2054856_-	microcin J25 efflux ABC transporter YojI	W8CYL7	Bacillus_phage	9.5e-14	24.0
WP_000884922.1\|2054931_2055582_-	DNA oxidative demethylase AlkB	A0A2K9L3R7	Tupanvirus	1.4e-05	31.7
WP_000786386.1\|2055581_2056646_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	1.8e-18	50.5
WP_000406116.1\|2056719_2057775_-	FAD:protein FMN transferase ApbE	NA	NA	NA	NA
WP_000865576.1\|2057886_2058978_-	porin OmpC	Q1MVN1	Enterobacteria_phage	9.4e-119	60.1
WP_001249127.1\|2059716_2062389_+	phosphotransferase RcsD	NA	NA	NA	NA
WP_001061917.1\|2062405_2063056_+	transcriptional regulator RcsB	NA	NA	NA	NA
2063062:2063080	attL	NA	NA	NA	NA
WP_000876014.1\|2063141_2065991_-	two-component system sensor histidine kinase RcsC	A0A1V0SGX0	Hokovirus	1.4e-41	27.2
WP_001225855.1\|2066265_2067042_-	YfaP family protein	NA	NA	NA	NA
WP_001104541.1\|2067046_2068696_-	DUF2300 domain-containing protein	NA	NA	NA	NA
WP_001676637.1\|2068696_2073091_-	alpha-2-macroglobulin family protein	NA	NA	NA	NA
WP_001025664.1\|2073892_2075215_+	type III secretion system effector NleA	H6WZN2	Escherichia_phage	2.5e-227	85.7
WP_001448330.1\|2075908_2076556_-	T3SS effector NleG family protein	B6DZC0	Enterobacteria_phage	2.4e-37	43.3
WP_001023397.1\|2076765_2077035_-\|tail	phage tail protein	B6DZB8	Enterobacteria_phage	3.2e-44	98.9
WP_106913835.1\|2077036_2078350_-\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	2.2e-77	98.9
WP_001228241.1\|2078414_2079014_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	2.4e-100	91.0
WP_001230644.1\|2079081_2079297_-	hypothetical protein	Q9LA64	Enterobacterial_phage	2.9e-32	95.8
WP_000099160.1\|2079359_2080898_-\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_000612626.1\|2080946_2081294_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839179.1\|2081290_2081695_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_032325348.1\|2081723_2085023_-	host specificity protein J	A5LH43	Enterobacteria_phage	0.0e+00	94.9
WP_000090884.1\|2085083_2085716_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	8.5e-96	99.0
WP_000194778.1\|2085652_2086396_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	6.6e-148	97.2
WP_001152619.1\|2086401_2087100_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	7.3e-133	99.1
WP_000847413.1\|2087099_2087429_-\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	1.3e-52	91.7
WP_000082375.1\|2087425_2089987_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	95.0
WP_000533403.1\|2089967_2090381_-\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_000479086.1\|2090407_2090839_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	4.8e-42	68.1
WP_001143013.1\|2090852_2091605_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	1.7e-127	93.6
WP_000683071.1\|2091612_2092008_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	4.2e-61	87.0
WP_000975037.1\|2092004_2092580_-\|tail	tail protein	A0A2R9YJK4	Escherichia_phage	7.5e-51	58.7
WP_001204544.1\|2092594_2092948_-\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	2.5e-41	69.2
WP_000201528.1\|2092940_2093315_-	hypothetical protein	NA	NA	NA	NA
WP_000522643.1\|2093366_2094251_-	hypothetical protein	C6ZCY2	Enterobacteria_phage	6.5e-94	54.1
WP_000256849.1\|2094308_2094656_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.5e-22	58.1
WP_001254039.1\|2094692_2096198_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.6e-100	54.0
WP_001430223.1\|2096187_2097780_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	1.1e-184	61.3
WP_000258991.1\|2097776_2097983_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	4.2e-12	60.0
WP_024017589.1\|2097966_2099895_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	2.7e-262	66.4
WP_000235436.1\|2099866_2100376_-\|terminase	terminase	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_001427981.1\|2100770_2100965_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.4e-27	95.3
WP_000738423.1\|2101324_2101618_+	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
WP_001228695.1\|2101708_2101891_-\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_000075153.1\|2102107_2102605_-	lysozyme	A0A1B5FP97	Escherichia_phage	1.6e-89	96.4
WP_000284524.1\|2102604_2102820_-\|holin	holin	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_012578864.1\|2102962_2103361_+	hypothetical protein	H6WZJ8	Escherichia_phage	6.9e-11	83.3
WP_000499454.1\|2103441_2103600_-	DUF3927 family protein	NA	NA	NA	NA
WP_001302581.1\|2103685_2104429_-	hypothetical protein	NA	NA	NA	NA
WP_001235460.1\|2104681_2105305_-	antitermination protein	K7PM87	Enterobacteria_phage	9.8e-113	98.6
WP_001028854.1\|2105301_2105967_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001223927.1\|2105963_2106566_-	recombination protein NinG	A0A1U9AJF8	Stx1_converting_phage	1.6e-91	94.6
WP_001108084.1\|2106540_2107107_-	endonuclease	A0A1U9AJK5	Stx1_converting_phage	6.6e-108	99.5
WP_001429269.1\|2107600_2109436_+	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	0.0e+00	99.7
WP_001254228.1\|2109939_2110122_-	NinE family protein	A0A1U9AJF6	Stx1_converting_phage	1.1e-29	100.0
WP_000153270.1\|2110118_2110646_-	phage N-6-adenine-methyltransferase	K7PJZ4	Enterobacterial_phage	9.5e-101	100.0
WP_000810176.1\|2110642_2111089_-	recombination protein NinB	A0A0N7C2V1	Escherichia_phage	3.4e-75	92.6
WP_000229807.1\|2111096_2111303_-	hypothetical protein	G8C7M4	Escherichia_phage	1.8e-26	97.1
WP_000145926.1\|2111375_2111666_-	protein ren	O48423	Enterobacteria_phage	9.6e-47	100.0
WP_000788878.1\|2111662_2112364_-	Replication protein 14	K7P6G2	Enterobacteria_phage	1.7e-129	99.6
WP_032325349.1\|2112360_2113299_-	replication protein	C1JJ53	Enterobacteria_phage	1.8e-171	99.7
WP_000035947.1\|2113331_2113628_-	hypothetical protein	A0A0N7C1W0	Escherichia_phage	1.3e-46	96.9
WP_000276885.1\|2113737_2113923_-	hypothetical protein	K7PHK4	Enterobacteria_phage	1.2e-26	100.0
WP_001095982.1\|2114003_2114654_+	LexA family transcriptional regulator	K7PM82	Enterobacteria_phage	4.9e-123	100.0
WP_000256573.1\|2114968_2115274_+	hypothetical protein	K7PJM7	Enterobacteria_phage	7.0e-48	99.0
WP_000930321.1\|2115276_2115615_+	hypothetical protein	K7PJW2	Enterobacteria_phage	5.8e-59	99.1
WP_000167595.1\|2115748_2116219_+	hypothetical protein	A0A1I9LJN4	Stx_converting_phage	3.7e-88	100.0
WP_000065385.1\|2116368_2116737_+	DUF2528 family protein	M1FPD2	Enterobacteria_phage	3.8e-64	97.5
WP_001198860.1\|2116809_2116974_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	A0A0N6WES3	Escherichia_phage	1.4e-26	100.0
WP_000372926.1\|2116942_2117107_+	host cell division inhibitory peptide Kil	A0A0P0ZC96	Stx2-converting_phage	3.2e-23	98.1
WP_000995439.1\|2117161_2117458_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000100847.1\|2117463_2118249_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000186740.1\|2118245_2118923_+	YqaJ viral recombinase family protein	A0A1I9LJM9	Stx_converting_phage	4.6e-132	100.0
WP_001303590.1\|2118922_2119105_+	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	7.4e-29	100.0
WP_000548547.1\|2119077_2119269_+	DUF1382 family protein	A0A1I9LJM8	Stx_converting_phage	1.9e-27	100.0
WP_001444000.1\|2119279_2119561_+	cell division protein ZapA	A0A0P0ZBQ0	Stx2-converting_phage	1.9e-47	100.0
WP_000763358.1\|2119659_2119881_+	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	1.6e-33	95.9
WP_001289868.1\|2119877_2120483_+	ead/Ea22-like family protein	A0A0K2FJF6	Enterobacteria_phage	1.7e-45	96.9
WP_001345188.1\|2120479_2120830_+	DUF551 domain-containing protein	A0A077SK54	Escherichia_phage	3.3e-33	80.2
WP_000457736.1\|2120904_2121147_+	DUF4222 domain-containing protein	H6WZF9	Escherichia_phage	3.7e-36	96.2
WP_001281192.1\|2121265_2121610_+	hypothetical protein	K7PJY7	Enterobacterial_phage	5.3e-60	100.0
WP_001444001.1\|2121715_2121934_+	excisionase	K7PKU2	Enterobacteria_phage	2.4e-34	98.6
WP_000533670.1\|2121911_2122982_+\|integrase	tyrosine-type recombinase/integrase	K7PHK0	Enterobacteria_phage	1.1e-196	98.0
WP_001215756.1\|2122996_2123602_-	DUF1175 domain-containing protein	NA	NA	NA	NA
WP_000012302.1\|2123598_2125287_-	DUF2138 domain-containing protein	NA	NA	NA	NA
WP_001281242.1\|2125435_2128063_-	DNA topoisomerase (ATP-hydrolyzing) subunit A	G3M9Z5	Bacillus_virus	8.1e-92	30.4
2137278:2137296	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2503150 : 2614612

108

Stx2-converting_phage(33.8%)

capsid,tRNA,terminase,holin,integrase,head,tail,transposase

attL 2600493:2600507|attR 2612853:2612867

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001298974.1\|2503150_2503888_-\|tRNA	tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase TrmN	NA	NA	NA	NA
WP_000219193.1\|2504019_2505354_+	ATP-dependent RNA helicase SrmB	E3T5E1	Cafeteria_roenbergensis_virus	2.9e-45	30.8
WP_001341633.1\|2505562_2506444_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000189207.1\|2506546_2507134_+	cysteine/O-acetylserine transporter	NA	NA	NA	NA
WP_000627807.1\|2507189_2507573_-	autonomous glycyl radical cofactor GrcA	Q7Y524	Enterobacteria_phage	1.4e-32	72.0
WP_001262716.1\|2507877_2508567_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	7.1e-56	48.8
WP_000997403.1\|2508614_2509652_-\|tRNA	tRNA/rRNA methyltransferase	NA	NA	NA	NA
WP_001098726.1\|2509858_2510278_+	thioredoxin TrxC	A0A0K2FIM3	Achromobacter_phage	2.8e-15	38.5
WP_001341635.1\|2510346_2511045_+	DTW domain-containing protein	NA	NA	NA	NA
WP_000083007.1\|2511076_2513737_+	protein lysine acetyltransferase	NA	NA	NA	NA
WP_000949265.1\|2513850_2515206_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_001300818.1\|2515251_2515575_+	YfiM family lipoprotein	NA	NA	NA	NA
WP_000841103.1\|2515571_2516870_-	alpha-ketoglutarate permease	Q6JIH2	Burkholderia_virus	1.3e-45	32.2
WP_001235102.1\|2522722_2525296_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	2.6e-127	35.3
WP_000040115.1\|2525425_2526157_-	polyphenol oxidase	NA	NA	NA	NA
WP_000079094.1\|2526153_2527134_-	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_000197686.1\|2527268_2528006_+	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_000178456.1\|2528276_2528618_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_001386991.1\|2528721_2528769_+	hypothetical protein	NA	NA	NA	NA
WP_000200116.1\|2528867_2530028_+	bifunctional chorismate mutase/prephenate dehydratase	NA	NA	NA	NA
WP_000225221.1\|2530070_2531192_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_001168054.1\|2531202_2532273_-	3-deoxy-7-phosphoheptulonate synthase AroF	A0A0F6R6T6	Escherichia_coli_O157_typing_phage	5.3e-90	51.2
WP_000976004.1\|2532482_2532848_+	DUF2799 domain-containing protein	NA	NA	NA	NA
WP_001212391.1\|2532997_2533516_+	YfiR family protein	NA	NA	NA	NA
WP_000969036.1\|2533505_2534732_+	diguanylate cyclase DgcN	NA	NA	NA	NA
WP_000589828.1\|2534747_2535230_+	OmpA family protein	NA	NA	NA	NA
WP_000065253.1\|2535306_2535654_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000264777.1\|2535695_2536463_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_000043335.1\|2536493_2537042_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000256450.1\|2537060_2537309_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_000460032.1\|2537557_2538919_-	signal recognition particle protein	NA	NA	NA	NA
WP_001338897.1\|2539085_2539877_+	inner membrane protein YpjD	NA	NA	NA	NA
WP_010723175.1\|2539897_2541184_+	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001296310.1\|2541238_2541832_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_001059169.1\|2541954_2542833_+	NAD(+) kinase	NA	NA	NA	NA
WP_000880910.1\|2542918_2544580_+	DNA repair protein RecN	NA	NA	NA	NA
WP_001203437.1\|2544728_2545070_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_001117838.1\|2545131_2545422_-	RnfH family protein	NA	NA	NA	NA
WP_000600190.1\|2545411_2545888_-	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_032324018.1\|2546019_2546502_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-28	46.2
WP_032324038.1\|2549993_2553395_-	type III secretion system effector EspN	A0A0N7KZG3	Stx2-converting_phage	1.0e-219	39.3
WP_001301673.1\|2553986_2556335_-	type III secretion system effector E3 ubiquitin ligase NleL	NA	NA	NA	NA
WP_115801847.1\|2556354_2556444_-	hypothetical protein	NA	NA	NA	NA
WP_001023420.1\|2556550_2556820_-\|tail	phage tail protein	H6WZN0	Escherichia_phage	3.8e-45	100.0
WP_000268987.1\|2556821_2558135_-\|tail	tail fiber protein	A0A0P0ZD68	Stx2-converting_phage	4.8e-77	98.6
WP_001228241.1\|2558199_2558799_-	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	2.4e-100	91.0
WP_001339397.1\|2558861_2559539_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|2559538_2559886_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381395.1\|2559905_2561477_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_085948186.1\|2562021_2563177_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_122996338.1\|2566553_2567186_-\|tail	tail assembly protein	Q6H9T3	Enterobacteria_phage	4.9e-104	97.1
WP_000194787.1\|2567131_2567875_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.1e-146	97.2
WP_001341641.1\|2567885_2568584_-\|tail	phage minor tail protein L	Q9EYE3	Enterobacteria_phage	7.6e-130	97.4
WP_000807927.1\|2568583_2568925_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	4.3e-62	98.2
WP_000212998.1\|2568917_2572160_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	95.5
WP_122993730.1\|2572210_2572420_-	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	2.6e-30	92.8
WP_000710952.1\|2572515_2572890_-\|tail	tail assembly protein	A0A0P0ZE84	Stx2-converting_phage	4.6e-65	100.0
WP_001275441.1\|2572904_2573621_-\|tail	tail protein	A0A0P0ZDV1	Stx2-converting_phage	3.6e-127	99.6
WP_000133393.1\|2573687_2574032_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	9.4e-57	99.1
WP_000573391.1\|2574028_2574475_-	HK97 gp10 family phage protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
WP_001007889.1\|2574471_2574822_-\|head	phage head closure protein	A0A0P0ZDP7	Stx2-converting_phage	2.7e-59	100.0
WP_000125996.1\|2574832_2575159_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	1.6e-53	99.1
WP_001063099.1\|2577685_2577907_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_032325321.1\|2577951_2579730_-\|capsid	phage major capsid protein	A0A0P0ZCT9	Stx2-converting_phage	0.0e+00	90.1
WP_032323913.1\|2579793_2581455_-\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.5
WP_000958380.1\|2581451_2582015_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_025380422.1\|2582303_2582669_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	5.8e-65	99.2
WP_000095736.1\|2582710_2582938_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_085948186.1\|2583424_2584581_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_050438101.1\|2584702_2585611_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.8e-68	45.1
WP_000088311.1\|2585556_2585859_-\|transposase	transposase	NA	NA	NA	NA
WP_047091958.1\|2586150_2586336_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.3e-17	98.3
WP_000992122.1\|2586854_2587388_-	lysozyme	A0A0N7KZF9	Stx2-converting_phage	2.8e-100	98.3
WP_000731236.1\|2587438_2587783_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-58	100.0
WP_000284519.1\|2587787_2588003_-\|holin	holin	Q6H9V8	Enterobacteria_phage	7.7e-33	98.6
WP_001290231.1\|2588079_2588352_-	DUF826 domain-containing protein	A0A0P0ZBB8	Stx2-converting_phage	2.2e-21	100.0
WP_000143462.1\|2588392_2588572_-	DUF1378 family protein	A0A0P0ZCJ7	Stx2-converting_phage	3.7e-25	100.0
WP_032212763.1\|2588707_2590645_-	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	0.0e+00	96.7
WP_001131907.1\|2592678_2593227_+	hypothetical protein	NA	NA	NA	NA
WP_001205460.1\|2593239_2593581_-	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	4.2e-57	90.3
WP_001379493.1\|2593598_2594588_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	7.3e-195	99.7
WP_024220650.1\|2594595_2595405_-	KilA-N domain-containing protein	Q8SBE6	Shigella_phage	4.5e-150	97.8
WP_000767117.1\|2595424_2595814_-	RusA family crossover junction endodeoxyribonuclease	K7PH72	Enterobacteria_phage	7.1e-69	100.0
WP_000210187.1\|2595810_2596137_-	LexA family transcriptional regulator	A5LH73	Enterobacteria_phage	1.6e-53	100.0
WP_000066917.1\|2596133_2596787_-	phage N-6-adenine-methyltransferase	A5LH72	Enterobacteria_phage	1.9e-127	99.5
WP_001305611.1\|2596786_2597281_-	PerC family transcriptional regulator	A0A291AWV6	Escherichia_phage	1.5e-87	99.4
WP_000104954.1\|2597277_2598219_-	helix-turn-helix domain-containing protein	S5FM81	Shigella_phage	4.3e-144	99.7
WP_001250269.1\|2598208_2598388_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	7.8e-15	68.5
WP_000515845.1\|2598563_2599115_-	protein YmfL	S5FXP0	Shigella_phage	3.4e-101	99.5
WP_001191674.1\|2599107_2599368_-	helix-turn-helix transcriptional regulator	S5FKP1	Shigella_phage	7.1e-41	100.0
WP_001020634.1\|2599465_2600158_+	helix-turn-helix transcriptional regulator	S5FUZ3	Shigella_phage	1.0e-126	100.0
WP_000559922.1\|2600477_2600993_-	hypothetical protein	NA	NA	NA	NA
2600493:2600507	attL	NA	NA	NA	NA
WP_000135680.1\|2601463_2601826_+	hypothetical protein	Q8SBF8	Shigella_phage	8.6e-61	100.0
WP_000081319.1\|2601891_2602716_+	YfdQ family protein	Q8SBF9	Shigella_phage	5.0e-149	98.9
WP_106913837.1\|2602844_2603381_+	5'-deoxynucleotidase	A5LH62	Enterobacteria_phage	1.1e-99	98.9
WP_032323952.1\|2603371_2604250_+	phosphoadenosine phosphosulfate reductase family protein	A0A2R2Z314	Escherichia_phage	1.2e-169	94.5
WP_032323951.1\|2604246_2604450_+	hypothetical protein	A0A2R2Z313	Escherichia_phage	1.2e-30	94.0
WP_000476199.1\|2604442_2604682_+	hypothetical protein	S5MQM0	Escherichia_phage	3.7e-36	96.2
WP_000034210.1\|2604678_2605008_+	ead/Ea22-like family protein	A0A0H4ISY5	Shigella_phage	1.1e-25	37.5
WP_000206753.1\|2605009_2605873_+	DUF551 domain-containing protein	A0A088CE95	Shigella_phage	3.2e-69	53.6
WP_000457722.1\|2605957_2606200_+	DUF4222 domain-containing protein	Q6H9Z8	Enterobacteria_phage	1.8e-30	82.5
WP_000557643.1\|2606203_2606350_+	hypothetical protein	A0A0P0ZDP5	Stx2-converting_phage	1.7e-20	90.9
WP_000516611.1\|2606522_2607698_+	DUF3596 domain-containing protein	I6PDJ1	Cronobacter_phage	4.6e-204	91.2
WP_001431537.1\|2608180_2609089_+	DUF4760 domain-containing protein	A0A1B5FPC5	Escherichia_phage	2.3e-171	100.0
WP_001341819.1\|2609387_2610617_+\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	1.5e-234	100.0
WP_000448925.1\|2610655_2611072_+	hypothetical protein	A0A1B5FPM5	Escherichia_phage	1.1e-72	100.0
WP_000214985.1\|2611143_2612892_-	hypothetical protein	A0A1B5FPH1	Escherichia_phage	0.0e+00	100.0
2612853:2612867	attR	NA	NA	NA	NA
WP_000577251.1\|2612893_2614612_-	ATP-binding protein	A0A1B5FPD5	Escherichia_phage	6.5e-308	100.0

DBSCAN-SWA_13

2687534 : 2694674

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001272924.1\|2687534_2690096_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.7e-30	20.6
WP_001141347.1\|2690201_2690858_+	protein-serine/threonine phosphatase	A0A222YWF0	Escherichia_phage	5.6e-50	47.2
WP_001297141.1\|2690908_2691676_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	3.3e-70	56.7
WP_000847985.1\|2691871_2692780_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
WP_000590392.1\|2692776_2694039_+	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	1.3e-135	61.4
WP_001278994.1\|2694035_2694674_+	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0

DBSCAN-SWA_14

2846606 : 2853513

Stx2-converting_phage(50.0%)

transposase,integrase

attL 2844563:2844579|attR 2853648:2853664

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2844563:2844579	attL	NA	NA	NA	NA
WP_000381395.1\|2846606_2848178_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|2848197_2848545_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|2848544_2849222_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000082600.1\|2849616_2850345_-	Rha family transcriptional regulator	B5AX29	Iodobacteriophage	7.1e-14	41.2
WP_000852869.1\|2851253_2851913_-	DUF4145 domain-containing protein	M1PSB6	Streptococcus_phage	3.6e-33	33.9
WP_000935135.1\|2851905_2853513_-\|integrase	site-specific integrase	A0A059XK29	uncultured_phage	4.3e-11	28.0
2853648:2853664	attR	NA	NA	NA	NA

DBSCAN-SWA_15

3732357 : 3745690

Enterobacteria_phage(66.67%)

integrase,transposase

attL 3732175:3732197|attR 3746175:3746197

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3732175:3732197	attL	NA	NA	NA	NA
WP_001218979.1\|3732357_3733527_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.7e-198	88.1
WP_000119815.1\|3733546_3735406_+	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	1.8e-13	22.4
WP_000186475.1\|3735402_3735828_+	hypothetical protein	NA	NA	NA	NA
WP_000446132.1\|3736155_3736728_-	Polarity suppression protein	Q7M2A1	Enterobacteria_phage	2.2e-95	97.3
WP_000638629.1\|3736801_3737302_-	transactivation protein	NA	NA	NA	NA
WP_001283024.1\|3737298_3738033_-	hypothetical protein	Q7M2A2	Enterobacteria_phage	5.7e-128	98.0
WP_001149160.1\|3738584_3738851_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.9e-45	100.0
WP_106889314.1\|3738847_3739447_+	ash family protein	Q7M2A7	Enterobacteria_phage	1.3e-50	81.0
WP_001244665.1\|3739439_3739727_+	hypothetical protein	Q7M2A0	Enterobacteria_phage	8.6e-48	97.9
WP_000459320.1\|3739719_3740175_+	hypothetical protein	Q7M298	Enterobacteria_phage	6.1e-64	98.2
WP_000381395.1\|3740250_3741822_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|3741841_3742189_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|3742188_3742866_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000856729.1\|3743021_3743342_+	DUF5375 domain-containing protein	NA	NA	NA	NA
WP_000783645.1\|3743356_3745690_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	98.6
3746175:3746197	attR	NA	NA	NA	NA

DBSCAN-SWA_16

4344048 : 4375738

Stx2-converting_phage(36.36%)

transposase,integrase,protease

attL 4337900:4337916|attR 4376121:4376137

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4337900:4337916	attL	NA	NA	NA	NA
WP_071830505.1\|4344048_4345668_+\|transposase	ISL3-like element ISEc38 family transposase	NA	NA	NA	NA
WP_032325301.1\|4345664_4347236_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	2.2e-294	98.4
WP_001218841.1\|4347352_4348618_-\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	2.7e-77	38.3
WP_001188520.1\|4348997_4349573_-	transcriptional regulator	NA	NA	NA	NA
WP_000068905.1\|4349609_4351307_-	protein-disulfide reductase DsbD	NA	NA	NA	NA
WP_000883338.1\|4351282_4351621_-	divalent cation tolerance protein CutA	NA	NA	NA	NA
WP_000961959.1\|4351736_4353038_-	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_000069437.1\|4353155_4354592_-	aspartate ammonia-lyase	NA	NA	NA	NA
WP_001267448.1\|4354928_4355405_+	membrane protein FxsA	NA	NA	NA	NA
WP_000015837.1\|4355420_4356677_-	L-methionine/branched-chain amino acid transporter	NA	NA	NA	NA
WP_001026276.1\|4356952_4357246_+	co-chaperone GroES	K4F9I2	Cronobacter_phage	9.2e-13	45.4
WP_000729117.1\|4357289_4358936_+	chaperonin GroEL	A0A2I7SAK5	Vibrio_phage	5.3e-190	68.9
WP_000558209.1\|4359073_4359427_+	DUF4156 domain-containing protein	NA	NA	NA	NA
WP_000399685.1\|4359679_4360660_+\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
WP_000471889.1\|4360887_4363584_-	magnesium-translocating P-type ATPase	M1HLC0	Paramecium_bursaria_Chlorella_virus	9.0e-46	27.4
WP_001387276.1\|4363724_4363778_-	mgtA regulatory leader peptide MgtL	NA	NA	NA	NA
WP_032323928.1\|4363962_4364910_+	HTH-type transcriptional regulator TreR	C6ZCU4	Enterobacteria_phage	3.5e-13	21.8
WP_001297258.1\|4365028_4366450_+	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_001341327.1\|4366499_4368155_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_000187778.1\|4368548_4370687_+	anaerobic ribonucleoside-triphosphate reductase	A0A2I7QNQ7	Vibrio_phage	1.5e-266	64.5
WP_001106238.1\|4370845_4371310_+	anaerobic ribonucleoside-triphosphate reductase-activating protein	K4F9T1	Cronobacter_phage	1.1e-52	57.1
WP_000839179.1\|4371745_4372150_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_000612626.1\|4372146_4372494_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000099160.1\|4372542_4374081_+\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8
WP_001162171.1\|4374385_4375738_-\|protease	metalloprotease PmbA	NA	NA	NA	NA
4376121:4376137	attR	NA	NA	NA	NA

DBSCAN-SWA_17

4463273 : 4526785

Stx2-converting_phage(46.15%)

transposase,integrase,tRNA

attL 4472069:4472084|attR 4508518:4508533

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000399648.1\|4463273_4464254_-\|transposase	IS110-like element IS621 family transposase	NA	NA	NA	NA
WP_000047539.1\|4464530_4464917_-	2-iminobutanoate/2-iminopropanoate deaminase	NA	NA	NA	NA
WP_000148581.1\|4464989_4465451_-	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_000013046.1\|4465463_4466399_-	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	2.9e-52	40.2
WP_001296693.1\|4466402_4466537_-	pyr operon leader peptide	NA	NA	NA	NA
WP_000230273.1\|4466817_4467213_-	RidA family protein	NA	NA	NA	NA
WP_000500687.1\|4467343_4468057_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000256681.1\|4468127_4468721_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000583470.1\|4468865_4469318_+	YhcH/YjgK/YiaL family protein	NA	NA	NA	NA
WP_001074121.1\|4469440_4470952_+	hypothetical protein	NA	NA	NA	NA
WP_000012897.1\|4471128_4472142_-	ornithine carbamoyltransferase	NA	NA	NA	NA
4472069:4472084	attL	NA	NA	NA	NA
WP_000002953.1\|4472303_4472720_+	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_001059398.1\|4472765_4473269_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000416407.1\|4474711_4477567_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.3e-140	36.7
WP_000786398.1\|4477566_4478010_-	DNA polymerase III subunit chi	NA	NA	NA	NA
WP_000397144.1\|4478363_4479875_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	6.0e-47	38.0
WP_000584109.1\|4480141_4481242_+	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_001295681.1\|4481241_4482324_+	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_001332879.1\|4482442_4483945_-	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	2.1e-84	44.8
WP_000061768.1\|4484074_4485094_-	NADPH-dependent aldehyde reductase Ahr	A0A0G2Y405	Acanthamoeba_polyphaga_mimivirus	1.9e-44	30.4
WP_000772685.1\|4485537_4486800_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	2.8e-74	40.3
WP_000356577.1\|4487043_4487883_-	hypothetical protein	NA	NA	NA	NA
WP_000091133.1\|4488022_4489609_-	hypothetical protein	NA	NA	NA	NA
WP_001339397.1\|4489898_4490576_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000624622.1\|4490575_4490923_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_000381395.1\|4490942_4492514_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_001185332.1\|4492823_4493096_-	ogr/Delta-like zinc finger family protein	A0A2I8TV89	Erwinia_phage	8.3e-08	46.9
WP_000991130.1\|4493097_4493652_-	hypothetical protein	NA	NA	NA	NA
WP_000214377.1\|4493648_4494401_-	hypothetical protein	NA	NA	NA	NA
WP_001084853.1\|4495315_4495576_+	AlpA family transcriptional regulator	Q7M299	Enterobacteria_phage	4.6e-24	67.5
WP_000761643.1\|4495572_4496121_+	ash family protein	Q7M2A7	Enterobacteria_phage	5.9e-29	64.8
WP_001014979.1\|4496120_4496345_+	hypothetical protein	NA	NA	NA	NA
WP_000842358.1\|4496341_4496665_+	DUF5375 family protein	NA	NA	NA	NA
WP_000016235.1\|4496679_4499013_+	DNA primase	Q7M2A8	Enterobacteria_phage	0.0e+00	72.8
WP_000594911.1\|4499918_4500743_+	hypothetical protein	L7TR00	Rhizobium_phage	3.0e-16	35.5
WP_000227281.1\|4500791_4501364_-	hypothetical protein	Q858R9	Enterobacteria_phage	2.2e-71	69.0
WP_000177060.1\|4502717_4502975_+	hypothetical protein	NA	NA	NA	NA
WP_000175457.1\|4503533_4504301_-	Fe(3+) dicitrate ABC transporter ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
WP_000684856.1\|4504301_4505258_-	Fe(3+) dicitrate ABC transporter permease subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
WP_106889325.1\|4505254_4506253_-	iron-dicitrate ABC transporter permease FecC	NA	NA	NA	NA
WP_000879164.1\|4506249_4507152_-	Fe(3+) dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
WP_106889324.1\|4507196_4509521_-	Fe(3+) dicitrate transport protein FecA	NA	NA	NA	NA
4508518:4508533	attR	NA	NA	NA	NA
WP_001068910.1\|4509607_4510561_-	fec operon regulator FecR	NA	NA	NA	NA
WP_001283626.1\|4510557_4511079_-	RNA polymerase sigma factor FecI	NA	NA	NA	NA
WP_000555341.1\|4512829_4513087_+	hypothetical protein	NA	NA	NA	NA
WP_159026387.1\|4513819_4515178_+	esterase-like activity of phytase family protein	NA	NA	NA	NA
WP_000998019.1\|4515416_4516802_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.4e-259	89.3
WP_000612591.1\|4516851_4517199_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171523.1\|4517195_4517576_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_001221615.1\|4517930_4518365_-	hypothetical protein	NA	NA	NA	NA
WP_000271003.1\|4518352_4518754_-	hypothetical protein	NA	NA	NA	NA
WP_000221529.1\|4518919_4519489_-	inovirus Gp2 family protein	NA	NA	NA	NA
WP_000381395.1\|4520228_4521800_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|4521819_4522167_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|4522166_4522844_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_001344112.1\|4522911_4523088_-	hemolysin activation protein	NA	NA	NA	NA
WP_077221339.1\|4523721_4524000_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_000839179.1\|4524449_4524854_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.0e-70	100.0
WP_000612626.1\|4524850_4525198_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000099160.1\|4525246_4526785_+\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.9e-296	99.8

DBSCAN-SWA_18

5248063 : 5316890

Enterobacteria_phage(56.9%)

lysis,capsid,tRNA,integrase,terminase,head,tail,transposase,portal,protease

attL 5258224:5258270|attR 5308364:5308410

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000912342.1\|5248063_5249449_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.0e-45	34.8
WP_001143540.1\|5249484_5250006_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_000190288.1\|5250113_5250326_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_000729154.1\|5250327_5251194_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
WP_000776555.1\|5251674_5252217_+	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
WP_000988363.1\|5252436_5253129_+	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_000701359.1\|5253159_5255769_+	fimbrial biogenesis usher protein	NA	NA	NA	NA
WP_001350487.1\|5255747_5256788_+	type 1 fimbrin D-mannose specific adhesin FimH	NA	NA	NA	NA
WP_001255226.1\|5256798_5257314_+	fimbria assembly protein	NA	NA	NA	NA
WP_000805428.1\|5257316_5257949_-	fimbria biosynthesis transcriptional regulator FimZ	NA	NA	NA	NA
5258224:5258270	attL	NA	NA	NA	NA
WP_085948186.1\|5258977_5260134_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_106913845.1\|5260195_5260606_-\|integrase	integrase	A0A088CD23	Shigella_phage	2.6e-61	83.1
WP_000446905.1\|5260569_5260941_-	helix-turn-helix domain-containing protein	M1FJ59	Enterobacteria_phage	2.1e-46	81.0
WP_000488407.1\|5260912_5261191_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
WP_000763390.1\|5261238_5261457_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	4.9e-35	98.6
WP_001443983.1\|5261555_5261837_-	hypothetical protein	A0A0P0ZE02	Stx2-converting_phage	7.2e-47	98.9
WP_000548537.1\|5261847_5262039_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_000149544.1\|5262011_5262194_-	DUF1317 domain-containing protein	A0A1U8QQC1	Enterobacteria_phage	6.9e-27	96.7
WP_000611716.1\|5262190_5262871_-	YqaJ viral recombinase family protein	B6DZ61	Enterobacteria_phage	3.0e-131	98.2
WP_000100847.1\|5262867_5263653_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995439.1\|5263658_5263955_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000206913.1\|5264030_5264321_-	hypothetical protein	K7P6H3	Enterobacteria_phage	2.5e-26	82.4
WP_001444023.1\|5264787_5265108_-	hypothetical protein	NA	NA	NA	NA
WP_000066829.1\|5265243_5265507_-	hypothetical protein	A0A2H4FNC7	Salmonella_phage	4.2e-41	95.4
WP_000858975.1\|5265588_5266278_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.8e-92	75.0
WP_001067458.1\|5266382_5266613_+	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
WP_001182773.1\|5266682_5267222_+	hypothetical protein	M9NZI6	Enterobacteria_phage	2.6e-61	66.1
WP_159032309.1\|5267308_5268238_+	Replication protein O	M1FN81	Enterobacteria_phage	2.9e-108	66.7
WP_000788789.1\|5268234_5268936_+	Replication protein P	M1FJ72	Enterobacteria_phage	3.8e-129	98.7
WP_000152742.1\|5269140_5269488_-	hypothetical protein	NA	NA	NA	NA
WP_001415151.1\|5270240_5270849_+	hypothetical protein	Q9T1Q5	Acyrthosiphon_pisum_secondary_endosymbiont_phage	1.5e-33	67.3
WP_001038620.1\|5271148_5271565_+	HEPN domain-containing protein	NA	NA	NA	NA
WP_000520500.1\|5271543_5271945_+	hypothetical protein	NA	NA	NA	NA
WP_072097617.1\|5272068_5272170_+	hypothetical protein	NA	NA	NA	NA
WP_001053023.1\|5272166_5272622_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	3.1e-60	67.5
WP_000224914.1\|5272621_5272792_+	hypothetical protein	K7P7K0	Enterobacteria_phage	2.4e-13	69.8
WP_000774477.1\|5272784_5273075_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	6.0e-49	96.9
WP_001099712.1\|5273071_5273434_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	4.3e-60	96.5
WP_000971074.1\|5273430_5273571_+	YlcG family protein	K7PHH3	Enterobacteria_phage	6.5e-09	69.8
WP_001204791.1\|5273656_5274040_+	antitermination protein QuuD	A0A088CD47	Shigella_phage	4.4e-55	83.3
WP_000737278.1\|5274228_5275311_-	porin OmpD	Q1MVN1	Enterobacteria_phage	7.8e-166	80.6
WP_000839596.1\|5275899_5276115_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_032325290.1\|5276114_5276612_+	lysozyme	M1FJA0	Enterobacteria_phage	1.6e-89	96.4
WP_001228695.1\|5276828_5277011_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_000738423.1\|5277101_5277395_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	2.0e-44	91.8
WP_001427981.1\|5277754_5277949_-	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	7.4e-27	95.3
WP_000453558.1\|5278337_5278883_+	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	4.0e-94	98.3
WP_001027295.1\|5278857_5280783_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.7
WP_000198149.1\|5280779_5280986_+\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001444138.1\|5280982_5282584_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	8.5e-310	99.1
WP_000381395.1\|5283056_5284628_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|5284647_5284995_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|5284994_5285672_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_000088640.1\|5285712_5286591_+	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	1.7e-147	99.0
WP_001345004.1\|5286600_5286933_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	5.0e-55	99.1
WP_000063244.1\|5286988_5288014_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.8e-188	97.7
WP_000158868.1\|5288055_5288451_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	5.7e-58	95.5
WP_000752961.1\|5288462_5288837_+\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	8.0e-62	99.1
WP_000985132.1\|5288827_5289406_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.3e-79	99.0
WP_000683110.1\|5289402_5289798_+\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	2.9e-70	99.2
WP_001342267.1\|5289805_5290546_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	1.0e-129	98.0
WP_000479169.1\|5290561_5290984_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.1e-70	96.4
WP_000459457.1\|5290965_5291400_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_032324072.1\|5293949_5294279_+\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	2.6e-56	98.2
WP_001152557.1\|5294278_5294977_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	3.4e-130	96.6
WP_000090884.1\|5295662_5296295_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	8.5e-96	99.0
WP_000515439.1\|5296355_5299769_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	97.2
WP_001230523.1\|5299839_5300439_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	1.8e-108	97.5
WP_000279150.1\|5300503_5303464_+	membrane protein	A0A2D1UII2	Escherichia_phage	3.0e-58	98.3
WP_000885569.1\|5303463_5304048_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.5e-102	94.3
WP_000239881.1\|5304102_5304771_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000937502.1\|5304827_5305133_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.8e-12	76.5
WP_001226384.1\|5305316_5306801_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001201825.1\|5306987_5307941_-\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001177453.1\|5308453_5309215_-	DNA-binding transcriptional regulator EnvY	NA	NA	NA	NA
5308364:5308410	attR	NA	NA	NA	NA
WP_001224569.1\|5309397_5310288_-	DUF4434 family protein	NA	NA	NA	NA
WP_001375368.1\|5310288_5313261_-	bacteriophage adsorption protein NfrA	NA	NA	NA	NA
WP_000383941.1\|5313247_5315485_-	phage adsorption protein NrfB	NA	NA	NA	NA
WP_000420938.1\|5315753_5316890_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP027547

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

90 : 74362

Stx2-converting_phage(48.15%)

integrase,protease,transposase

attL 69986:70045|attR 76074:77337

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106881567.1\|90_1659_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.1e-157	55.8
WP_000631725.1\|1662_2010_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.2e-44	72.9
WP_001341423.1\|2006_2681_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	30.8
WP_136139077.1\|2611_3031_+	DUF1449 family protein	NA	NA	NA	NA
WP_106889344.1\|3968_7871_+\|protease	serine protease autotransporter EspP	Q9LA58	Enterobacterial_phage	7.2e-238	40.4
WP_136138333.1\|8674_9088_-	DUF1449 family protein	NA	NA	NA	NA
WP_106881565.1\|9086_10299_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	3.5e-167	98.6
WP_001341409.1\|11067_11388_+	hypothetical protein	NA	NA	NA	NA
WP_001291056.1\|14339_14672_-	hypothetical protein	NA	NA	NA	NA
WP_000157095.1\|14903_15239_+	molybdopterin-guanine dinucleotide biosynthesis protein MobC	NA	NA	NA	NA
WP_001341408.1\|15324_16173_-	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_000148286.1\|16750_17002_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_077776889.1\|17032_17254_-	hypothetical protein	NA	NA	NA	NA
WP_000038351.1\|17277_18168_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	4.4e-66	53.8
WP_001247865.1\|18232_18499_-	hypothetical protein	NA	NA	NA	NA
WP_000218854.1\|18591_19026_-	hypothetical protein	NA	NA	NA	NA
WP_000117628.1\|19753_20254_-	antirestriction protein ArdA	NA	NA	NA	NA
WP_032313270.1\|20715_21033_-	hypothetical protein	A0A0N7KZV3	Escherichia_phage	4.5e-05	55.8
WP_001276261.1\|21309_22029_-	plasmid SOS inhibition protein A	NA	NA	NA	NA
WP_001341455.1\|22025_22508_-	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
WP_000274418.1\|22552_22987_-	DUF1380 domain-containing protein	NA	NA	NA	NA
WP_001443814.1\|22998_23217_-	hypothetical protein	NA	NA	NA	NA
WP_032324142.1\|23216_23900_-	DNA methylase	A0A2I7RE86	Vibrio_phage	2.1e-28	36.7
WP_001431782.1\|24283_24721_-	DUF1281 domain-containing protein	NA	NA	NA	NA
WP_000921957.1\|25459_26419_+	plasmid stabilization protein	A0A222YXF2	Escherichia_phage	5.4e-62	40.9
WP_000445934.1\|26418_26814_+	plasmid stabilization protein	NA	NA	NA	NA
WP_085948186.1\|27518_28675_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_001172748.1\|29041_29431_-	cytochrome b562 family protein	NA	NA	NA	NA
WP_000387727.1\|29474_31484_-	catalase/peroxidase KatP	NA	NA	NA	NA
WP_101981703.1\|31471_31684_-	hypothetical protein	NA	NA	NA	NA
WP_086163899.1\|31792_31891_-	AMP nucleosidase	A0A0N7BTS3	Escherichia_phage	2.5e-07	100.0
WP_106881565.1\|31856_33070_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	3.5e-167	98.6
WP_000361610.1\|33875_34853_+	RepB family plasmid replication initiator protein	J9Q7H0	Salmonella_phage	1.4e-100	59.2
WP_000381395.1\|35099_36671_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	9.9e-170	58.7
WP_000624622.1\|36690_37038_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-46	76.6
WP_001339397.1\|37037_37715_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	3.3e-21	46.0
WP_106913852.1\|37755_37950_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	5.9e-24	100.0
WP_001341423.1\|38003_38678_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	30.8
WP_000631725.1\|38674_39022_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.2e-44	72.9
WP_106881567.1\|39025_40594_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.1e-157	55.8
WP_000091308.1\|41417_41783_+	hypothetical protein	NA	NA	NA	NA
WP_000937603.1\|41782_42970_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_000422675.1\|46948_47425_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	3.0e-45	90.7
WP_001443774.1\|50551_50782_+\|transposase	transposase	NA	NA	NA	NA
WP_000907857.1\|61358_62390_-	replication initiation protein	NA	NA	NA	NA
WP_000335839.1\|63098_63740_+	transcription termination factor NusG	NA	NA	NA	NA
WP_000154135.1\|63880_64546_+	hypothetical protein	NA	NA	NA	NA
WP_106881567.1\|65205_66774_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.1e-157	55.8
WP_000631725.1\|66777_67125_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	9.2e-44	72.9
WP_001341423.1\|67121_67796_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	30.8
WP_001066949.1\|67849_68236_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_000704534.1\|68363_69224_+	alpha/beta hydrolase	A2RQC8	Archaeal_BJ1_virus	1.3e-09	23.5
WP_157776129.1\|69712_69988_+	hypothetical protein	NA	NA	NA	NA
69986:70045	attL	NA	NA	NA	NA
WP_085948186.1\|70028_71185_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
WP_001165114.1\|71252_71798_+	hypothetical protein	NA	NA	NA	NA
WP_001044768.1\|71959_72376_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_001261287.1\|72372_72603_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_000465041.1\|73164_73578_+	hypothetical protein	NA	NA	NA	NA
WP_001164205.1\|73579_74362_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	1.2e-54	97.3
76074:77337	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP027546

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP027547

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection