CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP028165	Staphylococcus aureus strain CFSAN064037 chromosome, complete genome	1 crisprs	cas3,csa3,DEDDh,WYL,DinG	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP028165_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028165_1

928717-928805

Orphan

Consensus_repeat	Method
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP028165_1

>merge|NZ_CP028165|1|928717-928805|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTATTTTACAACTTTAGTTGTTAGGGGCTCTTATGCA

>NZ_CP028165|1|1|928717-928805|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTATT
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028165.1\|WP_000160304.1\|919199_919910_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP028165.1\|WP_001024102.1\|925226_925892_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP028165.1\|WP_000370933.1\|929142_930000_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP028165.1\|WP_000334466.1\|935401_937207_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP028165.1\|WP_107240656.1\|939460_941593_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP028165.1\|WP_000908616.1\|933246_935250_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226121
NZ_CP028165.1\|WP_001123307.1\|920674_921088_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP028165.1\|WP_000083812.1\|937887_939426_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP028165.1\|WP_103145525.1\|923853_924792_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP028165.1\|WP_000648723.1\|942038_943145_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP028165.1\|WP_000003759.1\|926043_926364_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP028165.1\|WP_000909236.1\|930067_930850_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP028165.1\|WP_000019740.1\|926365_927346_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP028165.1\|WP_000495686.1\|927611_928703_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028165.1\|WP_000070865.1\|920030_920474_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP028165.1\|WP_001065210.1\|931328_933254_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NZ_CP028165.1\|WP_001292149.1\|941604_942039_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP028165.1\|WP_000123402.1\|921545_922919_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP028165.1\|WP_000808817.1\|923592_923823_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028165.1\|WP_000220900.1\|928902_928995_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP028165.1\|WP_000160304.1\|919199_919910_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP028165.1\|WP_001024102.1\|925226_925892_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.54377e-47
NZ_CP028165.1\|WP_000370933.1\|929142_930000_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	4.35599e-58
NZ_CP028165.1\|WP_000334466.1\|935401_937207_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP028165.1\|WP_107240656.1\|939460_941593_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	7.58425e-67
NZ_CP028165.1\|WP_000908616.1\|933246_935250_-\|AAA-family-ATPase	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	1.17368e-29
NZ_CP028165.1\|WP_001123307.1\|920674_921088_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	4.41929e-45
NZ_CP028165.1\|WP_000083812.1\|937887_939426_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP028165.1\|WP_000909236.1\|930067_930850_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	5.40486e-98
NZ_CP028165.1\|WP_000648723.1\|942038_943145_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP028165.1\|WP_000003759.1\|926043_926364_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP028165.1\|WP_103145525.1\|923853_924792_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	1.22779e-128
NZ_CP028165.1\|WP_000070865.1\|920030_920474_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68
NZ_CP028165.1\|WP_001065210.1\|931328_933254_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.58898e-50
NZ_CP028165.1\|WP_001292149.1\|941604_942039_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP028165.1\|WP_000123402.1\|921545_922919_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP028165.1\|WP_000019740.1\|926365_927346_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.73825e-109

>NZ_CP028165.1|WP_000495686.1|927611_928703_+|hypothetical-protein
MFTYFKSALKNAKPQLLITLIYAFIAFAVIAGVYLLANFQLAKYVQTIAIYSQFGQKPPGDAYLKAIAILLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGIYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDNKVVTEPKNTKVETDKVTTSVETKTEKAQDSLIDNTTKTMTSDKPEDNQPK
>NZ_CP028165.1|WP_000019740.1|926365_927346_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHQAHHHAHVH
>NZ_CP028165.1|WP_000003759.1|926043_926364_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP028165.1|WP_001024102.1|925226_925892_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQVISGEQDIKDALTQFENETD
>NZ_CP028165.1|WP_103145525.1|923853_924792_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGRLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP028165.1|WP_000808817.1|923592_923823_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP028165.1|WP_000123402.1|921545_922919_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP028165.1|WP_001123307.1|920674_921088_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLSVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP028165.1|WP_000070865.1|920030_920474_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP028165.1|WP_000160304.1|919199_919910_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP028165.1|WP_000220900.1|928902_928995_+|hypothetical-protein
MTYGSIIAIVCALFVIFFIPYMEKNNKKKK
>NZ_CP028165.1|WP_000370933.1|929142_930000_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLIEKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKHQQIYYEVFPFEGNRVSLKEDETWMRDMICSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLAKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTTYTNEEDGAAKYLAKHFLAD
>NZ_CP028165.1|WP_000909236.1|930067_930850_-|ABC-transporter-ATP-binding-protein
MLITLNHVGRLKQGKPILQDVSWQIDEGDKWVLYGLNGAGKTTLLNILNTYEPATSGTVNLFGKMPGKLGYSAENVRQQIGFVSHSLLEKFQEGETVIDVVMSGAFKSIGLYKNVDDDIISEAHQLLKLVEMSDKAQQFIGYLSTGEKQRVMIARALMGQPRILILDEPAAGLDFIARESLLNILDSLSDTYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSYFFQKNVAVQKWNNRFSMAMLE
>NZ_CP028165.1|WP_001065210.1|931328_933254_-|ATP-dependent-helicase
MNNRILEDEWKPSDDVTLEDSALHAIRASSHVAIAAGPGAGKTELLAHKAGYLIETGMCPYPKKILAISFKTDAARNLQERVELRYGKGVEKRFESKTFDAFAKGILDQFIHALPKEYQPQKNYEIILNEKSLNDIINAYITEPYSYYSNWQYEYHINSVLRTMKETKLPIVSFEDDLYSWINERLWMALLNGKGNLKSSLTFSMISILVEYLLKENPLLVKALQATYSHVFLDEFQDTTHIQYNLLKTIFLKSNTVITAVGDNKQRIMGWAGALQNAFGIFKTDFNATQYTLLNNFRSAPNLVYIQNIFSKTLNDASIEVLPAGEWNKNEGVCEIWNFKNHNIEAILLASYISKWMKVENLKPRDFCIIVKQHEHIYAAEIMKELSKINIKSRIEKDYQDLLSEELVLLIIRFLKLSYEEKSPELWLNVIDEIIDMKYSDADSESINYLIIEKELVKMLDEVRKLYSNINDTNFNTQFAEILQEIVVFLGEDIIKATYPKYNQANYFNEVMQKMIDKLQYQNCISMRGLVQEFCGEYSIPIMTIHKSKGLEYHTVFFIGVEDDAFWSFSTQKEADKNAFFVALSRAKQKIIFTISEKRNILKFGEEKNILQETKNISELIQTLMDAGVPLIEKSGLDNIL
>NZ_CP028165.1|WP_000908616.1|933246_935250_-|AAA-family-ATPase
MLISELHISNFRSFGNESQMIEIADLTALIGANSSGKTSLIMALLRLFGQKNTDRTLIKTDFHIPESADISKINEIDLMIEAKVIFPELKLESPANIKTVPEFIKHLIIEETDADPYLRIRLKGKWIQGSTPEGNIEQELVYVKIPYGREEKEEDLTRVPIHHQKLIQMMYIPAMRDPAKQLKNASGTLLWRIFDGIDWPENLNDYIKSLTSPIETLFKEIPSIKDIQGILNNQWNKYHKDKRYSNSQFKFNGNSLQEFLKNAEILFNPTIDGNSVKVDSLGDGLKSLFYITLVSTLLEIENKQEKDDKPLLNILAIEEPENHISQHLLGRIVRNLKEISKKDNAQVILSSHNSSIIGKVDPEYIRHLQIQNSESIVNNITLPEKNDDAHTYIKEAVKAYPDLYFSKLVILGEGDSEEIVLPKLLSADNIYLDDFNISVVPLGGRYVNHMWKLLNDLSIPHVTLLDLDRERGGGDWGRIKYVLKQLDENNRCSEQLRTVLLIPSNTYHTYSMEEIEDFHNRKSNRLNSLNTWIEKLEKEDVFFSYPLDLDFTMLMSFQEEYQNTMERGPQIPKDSNSTEYDEKLKKSIQATLKNEKAIAKTYSEDEKKLMIWYNSLFLGRGKPSTHIAALKDIDENEIIENAPKELLRLIQRVKEKVGLVGGSNIDE
>NZ_CP028165.1|WP_000334466.1|935401_937207_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVTLQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP028165.1|WP_000083812.1|937887_939426_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIVGFKVLAPIMKFIMYILSVAVESLVHAHLLPVVSILVEPAKILFLNNAINHGVFTPLGTDQAAKVGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKTPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP028165.1|WP_107240656.1|939460_941593_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGEDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQVSVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAEQLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNEFMASLVSDLSEFLSLKLESIDTFMEDPQELETLLRNKFLERIKKQFI
>NZ_CP028165.1|WP_001292149.1|941604_942039_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP028165.1|WP_000648723.1|942038_943145_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

316481 : 324793

Staphylococcus_phage(16.67%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|316481_317267_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924215.1\|317392_318283_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062177.1\|318292_319639_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683919.1\|319752_320853_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	1.0e-08	30.6
WP_000624562.1\|320855_321533_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|321663_322770_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_103145517.1\|322993_324793_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	2.3e-53	35.8

DBSCAN-SWA_2

394446 : 403489

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364543.1\|394446_394965_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.1e-28	45.8
WP_000594980.1\|394986_397260_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	4.7e-64	29.5
WP_000749803.1\|397462_399742_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|400016_400277_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|400295_401435_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019179.1\|401457_402483_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|402484_403489_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_3

529011 : 647869

128

Staphylococcus_phage(86.61%)

tRNA,holin,tail,protease,plate,transposase,head,portal,integrase,terminase,capsid

attL 584065:584080|attR 656900:656915

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_107240616.1\|529011_535338_-	DUF1542 domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	1.9e-267	82.2
WP_000836469.1\|535664_535976_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
WP_001803813.1\|535997_538415_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_001025061.1\|538702_539884_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526539.1\|539993_540947_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764420.1\|540943_541507_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	1.2e-101	98.9
WP_000757543.1\|541626_542028_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|542601_543429_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|543431_543551_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|543662_544664_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|544785_545250_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159025.1\|545262_546444_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	8.6e-227	99.5
WP_000493882.1\|546454_547087_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-111	98.6
WP_000077346.1\|547093_548137_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	3.1e-196	99.1
WP_020977352.1\|548617_550120_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.1e-29	98.6
WP_000221182.1\|550641_550956_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	3.7e-52	96.2
WP_000989111.1\|550955_552248_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.0e-225	98.1
WP_000163240.1\|552265_552661_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	2.4e-72	99.2
WP_001032833.1\|553009_553864_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|554139_554364_-	hypothetical protein	NA	NA	NA	NA
WP_000671045.1\|554562_555033_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	4.8e-80	96.8
WP_001153740.1\|555145_555589_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|555575_556019_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168908.1\|556316_556952_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|557377_558091_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|558348_558651_+	hypothetical protein	NA	NA	NA	NA
WP_001200550.1\|558906_559272_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.2e-59	98.3
WP_000623471.1\|559268_559622_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453300.1\|559871_560705_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.7e-158	99.3
WP_000366159.1\|560916_561825_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	4.4e-138	99.7
WP_107240617.1\|561968_563285_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.6e-43	32.8
WP_000933822.1\|563454_564648_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109907.1\|565019_566612_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_001803969.1\|566908_567655_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.6e-141	98.0
WP_000669096.1\|567659_568133_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	6.1e-83	97.5
WP_000718107.1\|568198_568456_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778531.1\|568452_569454_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	1.9e-182	96.7
WP_000348361.1\|569458_570937_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	5.8e-281	97.2
WP_001803971.1\|571095_571551_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	2.8e-77	96.6
WP_001803972.1\|571853_572504_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.5e-50	78.7
WP_000070661.1\|572584_573580_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	4.3e-70	95.6
WP_000669041.1\|573655_574282_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.4e-76	80.8
WP_000627545.1\|574322_574667_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	3.0e-55	95.6
WP_000414229.1\|574764_575337_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
WP_000190484.1\|575712_576549_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000809858.1\|577355_577541_-	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|577542_577719_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|577729_578113_-	hypothetical protein	NA	NA	NA	NA
WP_000747809.1\|578799_579246_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001801861.1\|579697_579793_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791232.1\|579915_580017_+	hypothetical protein	NA	NA	NA	NA
WP_107240618.1\|580679_584792_-	ATP-binding protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	98.5
584065:584080	attL	NA	NA	NA	NA
WP_000072598.1\|585554_586754_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	3.7e-225	97.7
WP_043039510.1\|586746_588303_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	4.4e-287	98.8
WP_103145528.1\|588656_589376_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	8.9e-126	95.4
WP_001039437.1\|589500_590220_-\|protease	serine protease	A0A2H4PQP7	Staphylococcus_phage	7.1e-115	86.6
WP_001038876.1\|590277_591000_-\|protease	serine protease	A0A2H4PQN0	Staphylococcus_phage	3.5e-114	84.6
WP_001043716.1\|591057_591780_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	9.0e-126	94.6
WP_001039436.1\|591904_592612_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	8.2e-124	96.2
WP_001092777.1\|593566_594148_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	1.9e-49	60.1
WP_000550244.1\|595080_595554_+	hypothetical protein	NA	NA	NA	NA
WP_000543851.1\|595558_596350_+	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000782469.1\|596719_597703_-	leukocidin/hemolysin toxin family protein	A0A2H4PQH7	Staphylococcus_phage	6.8e-185	98.8
WP_000473589.1\|597704_598640_-	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	1.1e-171	98.4
WP_001086050.1\|599520_599925_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	3.4e-58	82.1
WP_107240619.1\|599988_600777_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	1.1e-140	95.4
WP_000825945.1\|602097_602562_+	hypothetical protein	A0EWV3	Staphylococcus_phage	6.1e-27	94.8
WP_107240620.1\|603766_604771_-	restriction endonuclease subunit S	A0A1W6JNN3	Staphylococcus_phage	8.0e-64	42.0
WP_107240621.1\|604754_606647_-	N-6 DNA methylase	A0A1W6JNK1	Staphylococcus_phage	1.9e-268	70.9
WP_107240622.1\|607034_608480_-	SH3 domain-containing protein	S4V6E6	Staphylococcus_phage	1.5e-289	97.7
WP_107240623.1\|608460_608898_-\|holin	phage holin	A0A0K1LLA7	Staphylococcus_phage	6.5e-71	96.6
WP_107240624.1\|608948_610961_-\|plate	BppU family phage baseplate upper protein	Q4ZA81	Staphylococcus_virus	0.0e+00	96.3
WP_107240625.1\|610973_612848_-	glucosaminidase domain-containing protein	Q4ZBX1	Staphylococcus_virus	0.0e+00	91.5
WP_107240626.1\|612984_613284_-	DUF2951 family protein	B7T0E7	Staphylococcus_virus	2.5e-29	78.8
WP_001790193.1\|613324_613498_-	XkdX family protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
WP_065315646.1\|613507_613885_-	DUF2977 domain-containing protein	Q4ZA86	Staphylococcus_virus	2.6e-60	99.2
WP_107240627.1\|613884_615708_-\|plate	BppU family phage baseplate upper protein	Q4ZA88	Staphylococcus_virus	0.0e+00	99.5
WP_107240628.1\|615707_617606_-	hypothetical protein	A0A059T5B2	Staphylococcus_phage	0.0e+00	98.1
WP_107240629.1\|617618_619505_-\|tail	phage tail protein	A0A059T677	Staphylococcus_phage	0.0e+00	99.8
WP_107240630.1\|619515_620457_-\|tail	phage tail family protein	A0A059T7K5	Staphylococcus_phage	1.2e-178	98.4
WP_107240631.1\|620471_623357_-\|terminase	terminase	M9NRJ5	Staphylococcus_phage	0.0e+00	95.8
WP_031911809.1\|623360_623645_-	hypothetical protein	A0A059T626	Staphylococcus_phage	3.4e-44	97.9
WP_000134336.1\|623689_624202_-	hypothetical protein	A0A059T5B1	Staphylococcus_phage	5.4e-93	100.0
WP_000057585.1\|624268_624826_-	hypothetical protein	A0A059T675	Staphylococcus_phage	4.1e-102	100.0
WP_000270192.1\|624826_625252_-	DUF3168 domain-containing protein	Q4ZBQ9	Staphylococcus_phage	5.5e-75	100.0
WP_107240632.1\|625264_625678_-	HK97 gp10 family phage protein	A0A0N9BAY5	Staphylococcus_phage	2.4e-75	99.3
WP_107240633.1\|625664_626000_-\|head	phage head closure protein	Q4ZBR2	Staphylococcus_phage	2.0e-59	99.1
WP_046597552.1\|626011_626362_-\|head,tail	phage head-tail adapter protein	A0A0H3U2R5	Staphylococcus_phage	2.7e-59	98.3
WP_000002930.1\|626367_626511_-	hypothetical protein	A0A059T673	Staphylococcus_phage	7.9e-18	100.0
WP_000235170.1\|626522_627437_-\|capsid	phage major capsid protein	A0A059T7K3	Staphylococcus_phage	1.3e-169	99.3
WP_107240634.1\|627453_628038_-	DUF4355 domain-containing protein	M9NRJ1	Staphylococcus_phage	9.9e-75	99.5
WP_107240635.1\|628133_629084_-\|head	phage head morphogenesis protein	A0A0H3U2Z4	Staphylococcus_phage	2.3e-174	98.4
WP_107240636.1\|629052_630477_-\|portal	phage portal protein	A0A0E3T9I6	Staphylococcus_phage	3.8e-269	98.3
WP_107240637.1\|630473_631697_-\|terminase	PBSX family phage terminase large subunit	A0A059T7K2	Staphylococcus_phage	3.5e-239	99.0
WP_000594089.1\|631689_632184_-\|terminase	terminase small subunit	A0A059T7P8	Staphylococcus_phage	4.9e-67	89.6
WP_000162701.1\|632511_632934_-	RinA family phage transcriptional activator	A0A0F6N3E5	Staphylococcus_phage	1.2e-74	100.0
WP_000989998.1\|632957_633104_-	hypothetical protein	A0A059T5A8	Staphylococcus_phage	2.2e-15	100.0
WP_046597490.1\|633104_633470_-	hypothetical protein	A0A059T670	Staphylococcus_phage	1.6e-59	100.0
WP_050957894.1\|633470_633644_-	transcriptional regulator	A0A059T7K1	Staphylococcus_phage	2.2e-22	100.0
WP_046597488.1\|633645_633834_-	hypothetical protein	A0A059T7P6	Staphylococcus_phage	1.4e-27	98.4
WP_046597487.1\|633830_634037_-	DUF1381 domain-containing protein	A0A059T622	Staphylococcus_phage	1.3e-21	100.0
WP_107240638.1\|634073_634610_-	dUTP diphosphatase	A0A1P8L6E0	Staphylococcus_phage	3.0e-94	98.9
WP_001065080.1\|634602_634851_-	DUF1024 family protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
WP_000695750.1\|635118_635529_-	hypothetical protein	A0A1P8CN10	Staphylococcus_phage	2.1e-47	69.1
WP_000774794.1\|635542_635785_-	hypothetical protein	A0A2I6PDM0	Staphylococcus_phage	8.6e-41	97.5
WP_057485226.1\|635788_636157_-	hypothetical protein	A0A0H4J337	Staphylococcus_phage	2.2e-51	98.4
WP_070001472.1\|636157_636343_-	DUF3113 family protein	A0A059T620	Staphylococcus_phage	3.5e-26	96.7
WP_107240639.1\|636347_636752_-	DUF1064 domain-containing protein	Q6R835	Staphylococcus_virus	8.7e-70	97.0
WP_001123688.1\|636762_636984_-	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_031902399.1\|636986_637202_-	hypothetical protein	A9CR72	Staphylococcus_phage	1.2e-33	98.6
WP_107240640.1\|637198_638440_-	AAA family ATPase	Q8SDW1	Staphylococcus_phage	1.2e-226	99.0
WP_107240641.1\|638436_638793_-	hypothetical protein	M9NS37	Staphylococcus_phage	6.9e-63	99.2
WP_107240642.1\|638792_639548_-	DnaD domain protein	C8CGZ1	Staphylococcus_phage	1.1e-129	91.2
WP_046597477.1\|640228_640654_-	single-stranded DNA-binding protein	A0A0E3XC62	Staphylococcus_phage	4.0e-73	100.0
WP_001043065.1\|640653_641292_-	ERF family protein	R4II59	Staphylococcus_phage	1.7e-115	100.0
WP_107240643.1\|641291_641771_-	siphovirus Gp157 family protein	Q4ZAD7	Staphylococcus_virus	3.4e-81	97.5
WP_000291089.1\|641785_642046_-	DUF1108 family protein	Q4ZBM7	Staphylococcus_phage	1.2e-43	100.0
WP_000048119.1\|642139_642301_-	DUF1270 family protein	A0A059T7J6	Staphylococcus_phage	4.3e-20	98.1
WP_001093507.1\|642315_642531_-	DUF771 domain-containing protein	B7T098	Staphylococcus_virus	6.3e-35	100.0
WP_050972079.1\|642543_643299_-	phage antirepressor KilAC domain-containing protein	A0A1X9H0A0	Staphylococcus_phage	8.7e-140	100.0
WP_000933365.1\|643300_643486_-	helix-turn-helix transcriptional regulator	A0A0H4IP57	Staphylococcus_phage	1.3e-25	100.0
WP_000394410.1\|643931_644414_+	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
WP_000398749.1\|644464_644632_-	hypothetical protein	Q4ZA65	Staphylococcus_virus	9.8e-20	98.2
WP_107240644.1\|644647_644887_-	helix-turn-helix transcriptional regulator	A0A2H4J306	uncultured_Caudovirales_phage	3.0e-38	97.5
WP_107240645.1\|645079_645412_+	helix-turn-helix transcriptional regulator	A0A1J0MFC1	Staphylococcus_phage	6.1e-37	73.6
WP_107240646.1\|645423_645885_+	ImmA/IrrE family metallo-endopeptidase	A0A2I6PEK4	Staphylococcus_phage	5.3e-63	80.8
WP_107240647.1\|645916_646597_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A2H4PQQ5	Staphylococcus_phage	5.7e-122	99.1
WP_000115736.1\|646804_647869_+\|integrase	tyrosine-type recombinase/integrase	B7T092	Staphylococcus_virus	2.3e-202	99.2
656900:656915	attR	NA	NA	NA	NA

DBSCAN-SWA_4

791062 : 803332

Staphylococcus_phage(76.47%)

coat,integrase,terminase

attL 786436:786455|attR 801355:801374

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
786436:786455	attL	NA	NA	NA	NA
WP_103145489.1\|791062_791632_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	5.1e-100	97.4
WP_103145497.1\|791628_791841_-	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	3.3e-28	87.1
WP_107240651.1\|791972_792500_-\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	1.2e-87	96.6
WP_000448775.1\|792550_792769_-	hypothetical protein	NA	NA	NA	NA
WP_103145488.1\|792786_793365_-	pathogenicity island protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.2e-27	38.4
WP_001190600.1\|793376_793718_-	hypothetical protein	Q4ZE66	Staphylococcus_phage	8.4e-58	99.1
WP_103145487.1\|794064_794706_-	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	1.2e-110	92.5
WP_103145486.1\|794702_795083_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	4.5e-68	97.6
WP_103145485.1\|795392_797102_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	5.1e-305	93.8
WP_103145484.1\|797115_797985_-	primase C-terminal domain-containing protein	Q4ZE74	Staphylococcus_phage	4.6e-161	94.1
WP_103145483.1\|798051_798378_-	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	8.9e-41	77.1
WP_001058489.1\|798380_798590_-	hypothetical protein	Q4ZE76	Staphylococcus_phage	1.6e-30	98.6
WP_000784893.1\|798582_798729_-	hypothetical protein	NA	NA	NA	NA
WP_103145482.1\|798725_799043_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	1.7e-49	96.2
WP_103145481.1\|799046_799259_-	helix-turn-helix transcriptional regulator	A0A1W6JQE8	Staphylococcus_phage	4.9e-24	82.8
WP_103145480.1\|799421_800099_+	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.2e-10	31.8
WP_103145479.1\|800115_801288_+\|integrase	tyrosine-type recombinase/integrase	A0A1W6JQD3	Staphylococcus_phage	7.8e-220	98.7
WP_000240646.1\|801356_802973_-	chaperonin GroEL	A0A240F779	uncultured_virus	1.5e-157	54.7
801355:801374	attR	NA	NA	NA	NA
WP_000917289.1\|803047_803332_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2

DBSCAN-SWA_5

2282454 : 2290274

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|2282454_2283510_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|2283509_2284196_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|2284170_2284644_-	DoxX family protein	NA	NA	NA	NA
WP_001093557.1\|2284985_2285426_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637683.1\|2285705_2286290_-	hypothetical protein	NA	NA	NA	NA
WP_001062966.1\|2286388_2287102_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	5.0e-52	43.5
WP_000941336.1\|2287105_2287525_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|2287526_2288195_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604519.1\|2288545_2289139_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	5.8e-38	42.9
WP_001217797.1\|2289122_2290274_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_6

2303751 : 2318353

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663031.1\|2303751_2304810_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	2.3e-21	26.4
WP_000197263.1\|2305104_2305653_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429017.1\|2306254_2307172_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.4
WP_000193751.1\|2307452_2308958_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930015.1\|2309304_2309799_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.8e-52	71.5
WP_001068497.1\|2309818_2310685_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|2311485_2311884_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855518.1\|2311846_2313952_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|2314069_2315041_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_031901244.1\|2315486_2315642_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|2315680_2316652_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245571.1\|2316638_2317595_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	7.2e-06	60.0
WP_000616869.1\|2317591_2318353_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	5.0e-18	31.6

DBSCAN-SWA_7

2561186 : 2569659

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025174670.1\|2561186_2561669_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.2e-20	44.0
WP_001010393.1\|2561655_2562780_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174052.1\|2562783_2563488_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	2.8e-47	42.1
WP_000848350.1\|2563487_2563751_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|2563752_2564424_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_043039658.1\|2564416_2566606_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-140	39.7
WP_000483719.1\|2566584_2568069_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.5e-45	31.5
WP_000030807.1\|2568061_2569090_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	6.5e-61	41.4
WP_000238666.1\|2569092_2569659_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage